WorldWideScience

Sample records for quantification theory type

  1. A Study of Tongue and Pulse Diagnosis in Traditional Korean Medicine for Stroke Patients Based on Quantification Theory Type II

    Mi Mi Ko

    2013-01-01

    Full Text Available In traditional Korean medicine (TKM, pattern identification (PI diagnosis is important for treating diseases. The aim of this study was to comprehensively investigate the relationship between the PI type and tongue diagnosis or pulse diagnosis variables. The study included 1,879 stroke patients who were admitted to 12 oriental medical university hospitals from June 2006 through March 2009. The status of the pulse and tongue was examined in each patient. Additionally, to investigate relatively important indicators related to specialist PI, the quantification theory type II analysis was performed regarding the PI type. In the first axis quantification of the external criteria, the Qi-deficiency and the Yin-deficiency patterns were located in the negative direction, while the dampness-phlegm (DP and fire-heat patterns were located in the positive direction. The explanatory variable with the greatest impact on the assessment was a fine pulse. In the second axis quantification, the external criteria were divided into either the DP or non-DP patterns. The slippery pulse exhibited the greatest effect on the division. This study attempted to build a model using a statistical method to objectively quantify PI and various indicators that constitute the unique diagnosis system of TKM. These results should assist the development of future diagnostic standards in stroke PI.

  2. Uncertainty quantification theory, implementation, and applications

    Smith, Ralph C

    2014-01-01

    The field of uncertainty quantification is evolving rapidly because of increasing emphasis on models that require quantified uncertainties for large-scale applications, novel algorithm development, and new computational architectures that facilitate implementation of these algorithms. Uncertainty Quantification: Theory, Implementation, and Applications provides readers with the basic concepts, theory, and algorithms necessary to quantify input and response uncertainties for simulation models arising in a broad range of disciplines. The book begins with a detailed discussion of applications where uncertainty quantification is critical for both scientific understanding and policy. It then covers concepts from probability and statistics, parameter selection techniques, frequentist and Bayesian model calibration, propagation of uncertainties, quantification of model discrepancy, surrogate model construction, and local and global sensitivity analysis. The author maintains a complementary web page where readers ca...

  3. Guarded Cubical Type Theory

    Birkedal, Lars; Bizjak, Aleš; Clouston, Ranald;

    2016-01-01

    types. This further expands the foundations of CTT as a basis for formalisation in mathematics and computer science. We present examples to demonstrate the expressivity of our type theory, all of which have been checked using a prototype type-checker implementation, and present semantics in a presheaf......This paper improves the treatment of equality in guarded dependent type theory (GDTT), by combining it with cubical type theory (CTT). GDTT is an extensional type theory with guarded recursive types, which are useful for building models of program logics, and for programming and reasoning with...... coinductive types. We wish to implement GDTT with decidable type-checking, while still supporting non-trivial equality proofs that reason about the extensions of guarded recursive constructions. CTT is a variation of Martin-L\\"of type theory in which the identity type is replaced by abstract paths between...

  4. Inductive types in homotopy type theory

    Awodey, Steve; Gambino, Nicola; Sojakova, Kristina

    2012-01-01

    Homotopy type theory is an interpretation of Martin-L\\"of's constructive type theory into abstract homotopy theory. There results a link between constructive mathematics and algebraic topology, providing topological semantics for intensional systems of type theory as well as a computational approach to algebraic topology via type theory-based proof assistants such as Coq. The present work investigates inductive types in this setting. Modified rules for inductive types, including types of well...

  5. Recurrence quantification analysis theory and best practices

    Jr, Jr; Marwan, Norbert

    2015-01-01

    The analysis of recurrences in dynamical systems by using recurrence plots and their quantification is still an emerging field.  Over the past decades recurrence plots have proven to be valuable data visualization and analysis tools in the theoretical study of complex, time-varying dynamical systems as well as in various applications in biology, neuroscience, kinesiology, psychology, physiology, engineering, physics, geosciences, linguistics, finance, economics, and other disciplines.   This multi-authored book intends to comprehensively introduce and showcase recent advances as well as established best practices concerning both theoretical and practical aspects of recurrence plot based analysis.  Edited and authored by leading researcher in the field, the various chapters address an interdisciplinary readership, ranging from theoretical physicists to application-oriented scientists in all data-providing disciplines.

  6. An approximation approach for uncertainty quantification using evidence theory

    Over the last two decades, uncertainty quantification (UQ) in engineering systems has been performed by the popular framework of probability theory. However, many scientific and engineering communities realize that there are limitations in using only one framework for quantifying the uncertainty experienced in engineering applications. Recently evidence theory, also called Dempster-Shafer theory, was proposed to handle limited and imprecise data situations as an alternative to the classical probability theory. Adaptation of this theory for large-scale engineering structures is a challenge due to implicit nature of simulations and excessive computational costs. In this work, an approximation approach is developed to improve the practical utility of evidence theory in UQ analysis. The techniques are demonstrated on composite material structures and airframe wing aeroelastic design problem

  7. Invariant types in NIP theories

    Simon, Pierre

    2014-01-01

    We study invariant types in NIP theories. Amongst other things: we prove a definable version of the (p,q)-theorem in theories of small or medium directionality; we construct a canonical retraction from the space of M-invariant types to that of M-finitely satisfiable types; we show some amalgamation results for invariant types and list a number of open questions.

  8. Linear contextual modal type theory

    Schack-Nielsen, Anders; Schürmann, Carsten

    Abstract. When one implements a logical framework based on linear type theory, for example the Celf system [?], one is immediately con- fronted with questions about their equational theory and how to deal with logic variables. In this paper, we propose linear contextual modal type theory that gives...

  9. Guarded dependent type theory with coinductive types

    Bizjak, Aleš; Grathwohl, Hans Bugge; Clouston, Ranald; Birkedal, Lars; Møgelberg, Rasmus Ejlers

    We present guarded dependent type theory, gDTT, an extensional dependent type theory with a later' modality and clock quantifiers for programming and proving with guarded recursive and coinductive types. The later modality is used to ensure the productivity of recursive definitions in a modular......, type based, way. Clock quantifiers are used for controlled elimination of the later modality and for encoding coinductive types using guarded recursive types. Key to the development of gDTT are novel type and term formers involving what we call delayed substitutions’. These generalise the applicative...... functor rules for the later modality considered in earlier work, and are crucial for programming and proving with dependent types. We show soundness of the type theory with respect to a denotational model....

  10. Computational semantics in type theory

    Ranta, Aarne

    2006-01-01

    This paper aims to show how Montague-style grammars can be completely formalized and thereby declaratively implemented by using the Grammatical Framework GF. The implementation covers the fundamental operations of Montague’s PTQ model: the construction of analysis trees, the linearization of trees into strings, and the interpretation of trees as logical formulas. Moreover, a parsing algorithm is derived from the grammar. Given that GF is a constructive type theory with dependent types, the te...

  11. A "Toy" Model for Operational Risk Quantification using Credibility Theory

    Hans B\\"uhlmann; Shevchenko, Pavel V.; Mario V. W\\"uthrich

    2009-01-01

    To meet the Basel II regulatory requirements for the Advanced Measurement Approaches in operational risk, the bank's internal model should make use of the internal data, relevant external data, scenario analysis and factors reflecting the business environment and internal control systems. One of the unresolved challenges in operational risk is combining of these data sources appropriately. In this paper we focus on quantification of the low frequency high impact losses exceeding some high thr...

  12. Application of the third theory of quantification in coal and gas outburst forecast

    WU Cai-fang; QIN Yong; ZHANG Xu-liang

    2004-01-01

    The essential principles of the third theory of quantification are discussed, the concept and calculated method of reaction degree are put forward which extend the applying range and scientificalness of the primary reaction. Taking the Zhongmacun Mine as example, on the base of analyzing the rules of gas geology synthetically and traversing the geological factors infecting coal and gas outburst, the paper adopts the method of combining carving up statistical units with the third theory of quantification, screens out 8 sensitive geological factors from 11 geological indexes and carries through the work of gas geology regionalism to the exploited area of Zhongmacun according to the researching result. The practice shows that it is feasible to apply the third theory of quantification to gas geology, which offers a new thought to screen the sensitive geological factors of gas outburst forecast.

  13. Causality in Time Series: Its Detection and Quantification by Means of Information Theory

    Hlaváčková-Schindler, Kateřina

    New York: Springer, 2008 - (Emmert-Streib, F.; Dehmer, M.), s. 183-207. (Computer Science). ISBN 978-0-387-84815-0 R&D Projects: GA MŠk 2C06001 Institutional research plan: CEZ:AV0Z10750506 Keywords : causality * time series * information theory Subject RIV: BD - Theory of Information http://library.utia.cas.cz/separaty/2009/AS/schindler-causality in time series its detection and quantification by means of information theory.pdf

  14. Logic in the 1930s: type theory and model theory

    Schiemer, Georg; Reck, Erich H.

    2013-01-01

    In historical discussions of twentieth-century logic, it is typically assumed that model theory emerged within the tradition that adopted first-order logic as the standard framework. Work within the type-theoretic tradition, in the style of Principia Mathematica, tends to be downplayed or ignored in this connection. Indeed, the shift from type theory to first-order logic is sometimes seen as involving a radical break that first made possible the rise of modern model theory. ...

  15. Uncertainty Quantification and Propagation in Nuclear Density Functional Theory

    Schunck, N.; McDonnell, J. D.; Higdon, D.; Sarich, J.; Wild, S. M.

    2015-01-01

    Nuclear density functional theory (DFT) is one of the main theoretical tools used to study the properties of heavy and superheavy elements, or to describe the structure of nuclei far from stability. While on-going efforts seek to better root nuclear DFT in the theory of nuclear forces [see Duguet et al., this issue], energy functionals remain semi-phenomenological constructions that depend on a set of parameters adjusted to experimental data in finite nuclei. In this paper, we review recent e...

  16. Some Properties of Type I' String Theory

    Schwarz, John H.

    1999-01-01

    The T-dual formulation of Type I superstring theory, sometimes called Type I' theory, has a number of interesting features. Here we review some of them including the role of D0-branes and D8-branes in controlling possible gauge symmetry enhancement.

  17. Completeness in Hybrid Type Theory

    Areces, Carlos; Blackburn, Patrick Rowan; Huertas, Antonia;

    2014-01-01

    We show that basic hybridization (adding nominals and @ operators) makes it possible to give straightforward Henkin-style completeness proofs even when the modal logic being hybridized is higher-order. The key ideas are to add nominals as expressions of type t, and to extend to arbitrary types...... the way we interpret @i in propositional and first-order hybrid logic. This means: interpret @iαa , where αa is an expression of any type a , as an expression of type a that rigidly returns the value that αa receives at the i-world. The axiomatization and completeness proofs are generalizations of those...... found in propositional and first-order hybrid logic, and (as is usual inhybrid logic) we automatically obtain a wide range of completeness results for stronger logics and languages. Our approach is deliberately low-tech. We don’t, for example, make use of Montague’s intensional type s, or Fitting...

  18. Uncertainty Quantification and Propagation in Nuclear Density Functional Theory

    Schunck, N; McDonnell, J D; Higdon, D; Sarich, J; Wild, S M

    2015-03-17

    Nuclear density functional theory (DFT) is one of the main theoretical tools used to study the properties of heavy and superheavy elements, or to describe the structure of nuclei far from stability. While on-going eff orts seek to better root nuclear DFT in the theory of nuclear forces, energy functionals remain semi-phenomenological constructions that depend on a set of parameters adjusted to experimental data in fi nite nuclei. In this paper, we review recent eff orts to quantify the related uncertainties, and propagate them to model predictions. In particular, we cover the topics of parameter estimation for inverse problems, statistical analysis of model uncertainties and Bayesian inference methods. Illustrative examples are taken from the literature.

  19. Uncertainty quantification and propagation in nuclear density functional theory

    Nuclear density functional theory (DFT) is one of the main theoretical tools used to study the properties of heavy and superheavy elements, or to describe the structure of nuclei far from stability. While on-going efforts seek to better root nuclear DFT in the theory of nuclear forces (see Duguet et al., this Topical Issue), energy functionals remain semi-phenomenological constructions that depend on a set of parameters adjusted to experimental data in finite nuclei. In this paper, we review recent efforts to quantify the related uncertainties, and propagate them to model predictions. In particular, we cover the topics of parameter estimation for inverse problems, statistical analysis of model uncertainties and Bayesian inference methods. Illustrative examples are taken from the literature. (orig.)

  20. A quantification of prospect theory in the health domain

    Attema, Arthur E.; Werner B.F. Brouwer; Olivier L'Haridon

    2013-01-01

    It is well-known that expected utility (EU) has empirical deficiencies. Prospect theory (PT) has developed as an alternative with more descriptive validity. However, PT’s full function had not yet been quantified in the health domain. This paper is therefore the first to simultaneously measure utility of life duration, probability weighting, and loss aversion in the health domain. We observe loss aversion and risk aversion for gains and losses, which for gains can be explained by probabilisti...

  1. Quantification of digital forensic hypotheses using probability theory

    Overill, RE; Silomon, JAM; Tse, HKS; Chow, KP

    2013-01-01

    The issue of downloading illegal material from a website onto a personal digital device is considered from the perspective of conventional (Pascalian) probability theory. We present quantitative results for a simple model system by which we analyse and counter the putative defence case that the forensically recovered illegal material was downloaded accidentally by the defendant. The model is applied to two actual prosecutions involving possession of child pornography.

  2. Quantification of Uncertainties in Nuclear Density Functional Theory

    Schunck, N., E-mail: schunck1@llnl.gov [Physics Division, Lawrence Livermore National Laboratory, Livermore, CA 94551 (United States); McDonnell, J.D. [Physics Division, Lawrence Livermore National Laboratory, Livermore, CA 94551 (United States); Higdon, D. [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Sarich, J.; Wild, S. [Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439 (United States)

    2015-01-15

    Reliable predictions of nuclear properties are needed as much to answer fundamental science questions as in applications such as reactor physics or data evaluation. Nuclear density functional theory is currently the only microscopic, global approach to nuclear structure that is applicable throughout the nuclear chart. In the past few years, a lot of effort has been devoted to setting up a general methodology to assess theoretical uncertainties in nuclear DFT calculations. In this paper, we summarize some of the recent progress in this direction. Most of the new material discussed here will be be published in separate articles.

  3. Quantification of Uncertainties in Nuclear Density Functional Theory

    Reliable predictions of nuclear properties are needed as much to answer fundamental science questions as in applications such as reactor physics or data evaluation. Nuclear density functional theory is currently the only microscopic, global approach to nuclear structure that is applicable throughout the nuclear chart. In the past few years, a lot of effort has been devoted to setting up a general methodology to assess theoretical uncertainties in nuclear DFT calculations. In this paper, we summarize some of the recent progress in this direction. Most of the new material discussed here will be be published in separate articles

  4. Application of quantification theory in risk assessment of mine flooding

    WANG Lian-guo; MIAO Xie-xing; DONG Xu; WU Yu

    2008-01-01

    Hundreds of mine flooding accidents have occurred in China since the 1950s. These flooding accidents result in sub-merged working faces, even entire coal mines, leading to tremendous economic losses. It is reported that among 601 state-owned mines in China, 285 mines are exposed to water-inrush risks. The water pressure is becoming larger and larger with the increase of mining depth, leading to an increase of water-inrush hazards. Only when the risk of mine flooding is predicted in a reasonable manner, can we take timely and effective measures to prevent mine flooding from taking place. In our investigation quantifica-tion(II) theory is used to study the risk prediction problem about mine flooding. By investigating the main factors which affect mine flooding, eight risk assessment items have been identified. The extent of risk is classified into 4 grades. Given the data from differ-ent periods in the Feicheng mining area, a prediction model for the risk of mine flooding is established. The test analysis indicates a model correlation coefficient of 0.97 and the incidence of discrimination is as high as 97.37%, which implies that the effect of the model is quite satisfactory. With the help of computers, this method can be widely applied.

  5. Quantification of margins and mixed uncertainties using evidence theory and stochastic expansions

    The objective of this paper is to implement Dempster–Shafer Theory of Evidence (DSTE) in the presence of mixed (aleatory and multiple sources of epistemic) uncertainty to the reliability and performance assessment of complex engineering systems through the use of quantification of margins and uncertainties (QMU) methodology. This study focuses on quantifying the simulation uncertainties, both in the design condition and the performance boundaries along with the determination of margins. To address the possibility of multiple sources and intervals for epistemic uncertainty characterization, DSTE is used for uncertainty quantification. An approach to incorporate aleatory uncertainty in Dempster–Shafer structures is presented by discretizing the aleatory variable distributions into sets of intervals. In view of excessive computational costs for large scale applications and repetitive simulations needed for DSTE analysis, a stochastic response surface based on point-collocation non-intrusive polynomial chaos (NIPC) has been implemented as the surrogate for the model response. The technique is demonstrated on a model problem with non-linear analytical functions representing the outputs and performance boundaries of two coupled systems. Finally, the QMU approach is demonstrated on a multi-disciplinary analysis of a high speed civil transport (HSCT). - Highlights: • Quantification of margins and uncertainties (QMU) methodology with evidence theory. • Treatment of both inherent and epistemic uncertainties within evidence theory. • Stochastic expansions for representation of performance metrics and boundaries. • Demonstration of QMU on an analytical problem. • QMU analysis applied to an aerospace system (high speed civil transport)

  6. Fixed point theory in metric type spaces

    Agarwal, Ravi P; O’Regan, Donal; Roldán-López-de-Hierro, Antonio Francisco

    2015-01-01

    Written by a team of leading experts in the field, this volume presents a self-contained account of the theory, techniques and results in metric type spaces (in particular in G-metric spaces); that is, the text approaches this important area of fixed point analysis beginning from the basic ideas of metric space topology. The text is structured so that it leads the reader from preliminaries and historical notes on metric spaces (in particular G-metric spaces) and on mappings, to Banach type contraction theorems in metric type spaces, fixed point theory in partially ordered G-metric spaces, fixed point theory for expansive mappings in metric type spaces, generalizations, present results and techniques in a very general abstract setting and framework. Fixed point theory is one of the major research areas in nonlinear analysis. This is partly due to the fact that in many real world problems fixed point theory is the basic mathematical tool used to establish the existence of solutions to problems which arise natur...

  7. Quantification of fibre type regionalisation : an analysis of lower hindlimb muscles in the rat

    Wang, LC; Kernell, D

    2001-01-01

    Newly developed concepts and methods for the quantification of fibre type regionalisation were used for comparison between all muscles traversing the ankle of the rat lower hindlimb (n = 13). For each muscle, cross-sections from the proximodistal midlevel were stained for myofibrillar ATPase and cla

  8. Explicit Substitutions for Contextual Type Theory

    Abel, Andreas; 10.4204/EPTCS.34.3

    2010-01-01

    In this paper, we present an explicit substitution calculus which distinguishes between ordinary bound variables and meta-variables. Its typing discipline is derived from contextual modal type theory. We first present a dependently typed lambda calculus with explicit substitutions for ordinary variables and explicit meta-substitutions for meta-variables. We then present a weak head normalization procedure which performs both substitutions lazily and in a single pass thereby combining substitution walks for the two different classes of variables. Finally, we describe a bidirectional type checking algorithm which uses weak head normalization and prove soundness.

  9. Uncertainty Quantification for Nuclear Density Functional Theory and Information Content of New Measurements

    McDonnell, J D; Higdon, D; Sarich, J; Wild, S M; Nazarewicz, W

    2015-01-01

    Statistical tools of uncertainty quantification can be used to assess the information content of measured observables with respect to present-day theoretical models; to estimate model errors and thereby improve predictive capability; to extrapolate beyond the regions reached by experiment; and to provide meaningful input to applications and planned measurements. To showcase new opportunities offered by such tools, we make a rigorous analysis of theoretical statistical uncertainties in nuclear density functional theory using Bayesian inference methods. By considering the recent mass measurements from the Canadian Penning Trap at Argonne National Laboratory, we demonstrate how the Bayesian analysis and a direct least-squares optimization, combined with high-performance computing, can be used to assess the information content of the new data with respect to a model based on the Skyrme energy density functional approach. Employing the posterior probability distribution computed with a Gaussian process emulator, w...

  10. Applications of Jungian Type Theory to Counselor Education.

    Dilley, Josiah S.

    1987-01-01

    Describes Carl Jung's theory of psychological type and the Myers-Briggs Type Indicator (MBTI), an instrument to assess Jungian type. Cites sources of information on the research and application of the theory and the MBTI. Explores how knowledge of type theory can be useful to counselor educators. (Author)

  11. Applicability of Information Theory to the Quantification of Responses to Anthropogenic Noise by Southeast Alaskan Humpback Whales

    J. Ellen Blue

    2008-05-01

    Full Text Available We assess the effectiveness of applying information theory to the characterization and quantification of the affects of anthropogenic vessel noise on humpback whale (Megaptera novaeangliae vocal behavior in and around Glacier Bay, Alaska. Vessel noise has the potential to interfere with the complex vocal behavior of these humpback whales which could have direct consequences on their feeding behavior and thus ultimately on their health and reproduction. Humpback whale feeding calls recorded during conditions of high vessel-generated noise and lower levels of background noise are compared for differences in acoustic structure, use, and organization using information theoretic measures. We apply information theory in a self-referential manner (i.e., orders of entropy to quantify the changes in signaling behavior. We then compare this with the reduction in channel capacity due to noise in Glacier Bay itself treating it as a (Gaussian noisy channel. We find that high vessel noise is associated with an increase in the rate and repetitiveness of sequential use of feeding call types in our averaged sample of humpback whale vocalizations, indicating that vessel noise may be modifying the patterns of use of feeding calls by the endangered humpback whales in Southeast Alaska. The information theoretic approach suggested herein can make a reliable quantitative measure of such relationships and may also be adapted for wider application to many species where environmental noise is thought to be a problem.

  12. Multi-level Contextual Type Theory

    Boespflug, Mathieu; 10.4204/EPTCS.71.3

    2011-01-01

    Contextual type theory distinguishes between bound variables and meta-variables to write potentially incomplete terms in the presence of binders. It has found good use as a framework for concise explanations of higher-order unification, characterize holes in proofs, and in developing a foundation for programming with higher-order abstract syntax, as embodied by the programming and reasoning environment Beluga. However, to reason about these applications, we need to introduce meta^2-variables to characterize the dependency on meta-variables and bound variables. In other words, we must go beyond a two-level system granting only bound variables and meta-variables. In this paper we generalize contextual type theory to n levels for arbitrary n, so as to obtain a formal system offering bound variables, meta-variables and so on all the way to meta^n-variables. We obtain a uniform account by collapsing all these different kinds of variables into a single notion of variabe indexed by some level k. We give a decidable ...

  13. Activity Theory as a Theoretical Framework for Health Self-Quantification: A Systematic Review of Empirical Studies

    2016-01-01

    Background Self-quantification (SQ) is a way of working in which, by using tracking tools, people aim to collect, manage, and reflect on personal health data to gain a better understanding of their own body, health behavior, and interaction with the world around them. However, health SQ lacks a formal framework for describing the self-quantifiers’ activities and their contextual components or constructs to pursue these health related goals. Establishing such framework is important because it is the first step to operationalize health SQ fully. This may in turn help to achieve the aims of health professionals and researchers who seek to make or study changes in the self-quantifiers’ health systematically. Objective The aim of this study was to review studies on health SQ in order to answer the following questions: What are the general features of the work and the particular activities that self-quantifiers perform to achieve their health objectives? What constructs of health SQ have been identified in the scientific literature? How have these studies described such constructs? How would it be possible to model these constructs theoretically to characterize the work of health SQ? Methods A systematic review of peer-reviewed literature was conducted. A total of 26 empirical studies were included. The content of these studies was thematically analyzed using Activity Theory as an organizing framework. Results The literature provided varying descriptions of health SQ as data-driven and objective-oriented work mediated by SQ tools. From the literature, we identified two types of SQ work: work on data (ie, data management activities) and work with data (ie, health management activities). Using Activity Theory, these activities could be characterized into 6 constructs: users, tracking tools, health objectives, division of work, community or group setting, and SQ plan and rules. We could not find a reference to any single study that accounted for all these activities and

  14. Uncertainty quantification for nuclear density functional theory and information content of new measurements

    McDonnell, J. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Schunck, N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Higdon, D. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sarich, J. [Argonne National Lab. (ANL), Argonne, IL (United States); Wild, S. M. [Argonne National Lab. (ANL), Argonne, IL (United States); Nazarewicz, W. [Michigan State Univ., East Lansing, MI (United States); Oak Ridge National Lab., Oak Ridge, TN (United States); Univ. of Warsaw, Warsaw (Poland)

    2015-03-24

    Statistical tools of uncertainty quantification can be used to assess the information content of measured observables with respect to present-day theoretical models, to estimate model errors and thereby improve predictive capability, to extrapolate beyond the regions reached by experiment, and to provide meaningful input to applications and planned measurements. To showcase new opportunities offered by such tools, we make a rigorous analysis of theoretical statistical uncertainties in nuclear density functional theory using Bayesian inference methods. By considering the recent mass measurements from the Canadian Penning Trap at Argonne National Laboratory, we demonstrate how the Bayesian analysis and a direct least-squares optimization, combined with high-performance computing, can be used to assess the information content of the new data with respect to a model based on the Skyrme energy density functional approach. Employing the posterior probability distribution computed with a Gaussian process emulator, we apply the Bayesian framework to propagate theoretical statistical uncertainties in predictions of nuclear masses, two-neutron dripline, and fission barriers. Overall, we find that the new mass measurements do not impose a constraint that is strong enough to lead to significant changes in the model parameters. As a result, the example discussed in this study sets the stage for quantifying and maximizing the impact of new measurements with respect to current modeling and guiding future experimental efforts, thus enhancing the experiment-theory cycle in the scientific method.

  15. Uncertainty quantification for nuclear density functional theory and information content of new measurements.

    McDonnell, J D; Schunck, N; Higdon, D; Sarich, J; Wild, S M; Nazarewicz, W

    2015-03-27

    Statistical tools of uncertainty quantification can be used to assess the information content of measured observables with respect to present-day theoretical models, to estimate model errors and thereby improve predictive capability, to extrapolate beyond the regions reached by experiment, and to provide meaningful input to applications and planned measurements. To showcase new opportunities offered by such tools, we make a rigorous analysis of theoretical statistical uncertainties in nuclear density functional theory using Bayesian inference methods. By considering the recent mass measurements from the Canadian Penning Trap at Argonne National Laboratory, we demonstrate how the Bayesian analysis and a direct least-squares optimization, combined with high-performance computing, can be used to assess the information content of the new data with respect to a model based on the Skyrme energy density functional approach. Employing the posterior probability distribution computed with a Gaussian process emulator, we apply the Bayesian framework to propagate theoretical statistical uncertainties in predictions of nuclear masses, two-neutron dripline, and fission barriers. Overall, we find that the new mass measurements do not impose a constraint that is strong enough to lead to significant changes in the model parameters. The example discussed in this study sets the stage for quantifying and maximizing the impact of new measurements with respect to current modeling and guiding future experimental efforts, thus enhancing the experiment-theory cycle in the scientific method. PMID:25860736

  16. Development of an exchange-correlation functional with uncertainty quantification capabilities for density functional theory

    Aldegunde, Manuel; Kermode, James R.; Zabaras, Nicholas

    2016-04-01

    This paper presents the development of a new exchange-correlation functional from the point of view of machine learning. Using atomization energies of solids and small molecules, we train a linear model for the exchange enhancement factor using a Bayesian approach which allows for the quantification of uncertainties in the predictions. A relevance vector machine is used to automatically select the most relevant terms of the model. We then test this model on atomization energies and also on bulk properties. The average model provides a mean absolute error of only 0.116 eV for the test points of the G2/97 set but a larger 0.314 eV for the test solids. In terms of bulk properties, the prediction for transition metals and monovalent semiconductors has a very low test error. However, as expected, predictions for types of materials not represented in the training set such as ionic solids show much larger errors.

  17. Field theory in Goedel-type spacetimes

    Marecki, Piotr [Institut fuer Theoretische Physik, Universitaet Leipzig, 04009 Leipzig (Germany)

    2008-07-01

    I will discuss mathematical aspects of the massless scalar field in spacetimes of Goedel type. Due to their high symmetry, these spacetimes might provide an arena for the next step of development of concrete models of quantum fields in curved spacetimes, such as these developed already for the de Sitter spacetime. While the motion of the sources of Goedel spacetimes (dust with non-vanishing vorticity) is physically interesting and not too-implausible, a difficulty with causality is encountered: sufficiently large regions of Goedel spacetimes posses CTCs. A complete picture of the classical solutions of the wave equation, which will be presented, sheds some light on the seriousness of this difficulty from the point of view of classical field theory and provides a link to known treatments of quantum fields in simple non-globally hyperbolic spacetimes such as time-like cylinders etc. I present an algebraic construction of the solutions based on the symmetry-generators of Goedel-type spacetimes and a connection to the analysis of unitary irreducible representations of SU(1,1).

  18. Simple Type Theory as Framework for Combining Logics

    Benzmueller, Christoph

    2010-01-01

    Simple type theory is suited as framework for combining classical and non-classical logics. This claim is based on the observation that various prominent logics, including (quantified) multimodal logics and intuitionistic logics, can be elegantly embedded in simple type theory. Furthermore, simple type theory is sufficiently expressive to model combinations of embedded logics and it has a well understood semantics. Off-the-shelf reasoning systems for simple type theory exist that can be uniformly employed for reasoning within and about combinations of logics.

  19. Toward a Theory of Psychological Type Congruence for Advertisers.

    McBride, Michael H.; And Others

    Focusing on the impact of advertisers' persuasive selling messages on consumers, this paper discusses topics relating to the theory of psychological type congruence. Based on an examination of persuasion theory and relevant psychological concepts, including recent cognitive stability and personality and needs theory and the older concept of…

  20. On Types of Observables in Constrained Theories

    Anderson, Edward

    2016-01-01

    The Kuchar observables notion is shown to apply only to a limited range of theories. Relational mechanics, slightly inhomogeneous cosmology and supergravity are used as examples that require further notions of observables. A suitably general notion of A-observables is then given to cover all of these cases. `A' here stands for `algebraic substructure'; A-observables can be defined by association with each closed algebraic substructure of a theory's constraints. Both constrained algebraic structures and associated notions of A-observables form bounded lattices.

  1. Numerical domain wall type solutions in φ4 theory

    The well known domain wall type solutions are nowadays of great physical interest in classical field theory. These solutions can mostly be found only approximately. Recently the Hilbert-Chapman-Enskog method was successfully applied to obtain this type solutions in Φ4 theory. The goal of the present paper is to verify these perturbative results by numerical computations. (author)

  2. Development and Assessment of a Multiplex Real-Time PCR Assay for Quantification of Human Immunodeficiency Virus Type 1 DNA▿

    Beloukas, A.; Paraskevis, D.; Haida, C.; Sypsa, V.; Hatzakis, A

    2009-01-01

    Previous studies showed that high levels of human immunodeficiency virus type 1 (HIV-1) DNA are associated with a faster progression to AIDS, an increased risk of death, and a higher risk of HIV RNA rebound in patients on highly active antiretroviral therapy. Our objective was to develop and assess a highly sensitive real-time multiplex PCR assay for the quantification of HIV-1 DNA (RTMP-HIV) based on molecular beacons. HIV-1 DNA quantification was carried out by RTMP in a LightCycler 2.0 app...

  3. Water type quantification in the Skagerrak, the Kattegat and off the Jutland west coast

    Trond Kristiansen

    2015-04-01

    Full Text Available An extensive data series of salinity, nutrients and coloured dissolved organic material (CDOM was collected in the Skagerrak, the northern part of the Kattegat and off the Jutland west coast in April each year during the period 1996–2000, by the Institute of Marine Research in Norway. In this month, after the spring bloom, German Bight Water differs from its surrounding waters by a higher nitrate content and higher nitrate/phosphate and nitrate/silicate ratios. The spreading of this water type into the Skagerrak is of special interest with regard to toxic algal blooms. The quantification of the spatial distributions of the different water types required the development of a new algorithm for the area containing the Norwegian Coastal Current, while an earlier Danish algorithm was applied for the rest of the area. From the upper 50 m a total of 2227 observations of salinity and CDOM content have been used to calculate the mean concentration of water from the German Bight, the North Sea (Atlantic water, the Baltic Sea and Norwegian rivers. The Atlantic Water was the dominant water type, with a mean concentration of 79%, German Bight Water constituted 11%, Baltic Water 8%, and Norwegian River Water 2%. At the surface the mean percentages of these water types were found to be 68%, 15%, 15%, and 3%, respectively. Within the northern part of the Skagerrak, closer to the Norwegian coast, the surface waters were estimated to consist of 74% Atlantic Water, 20% Baltic Water, and 7% Norwegian River Water. The analysis indicates that the content of German Bight Water in this part is less than 5%.

  4. Closed tachyon solitons in type II string theory

    García-Etxebarria, Iñaki; Uranga, Angel M

    2015-01-01

    Type II theories can be described as the endpoint of closed string tachyon condensation in certain orbifolds of supercritical type 0 theories. In this paper, we study solitons of this closed string tachyon and analyze the nature of the resulting defects in critical type II theories. The solitons are classified by the real K-theory groups KO of bundles associated to pairs of supercritical dimensions. For real codimension 4 and 8, corresponding to $KO({\\bf S}^4)={\\bf Z}$ and $KO({\\bf S}^8)={\\bf Z}$, the defects correspond to a gravitational instanton and a fundamental string, respectively. We apply these ideas to reinterpret the worldsheet GLSM, regarded as a supercritical theory on the ambient toric space with closed tachyon condensation onto the CY hypersurface, and use it to describe charged solitons under discrete isometries. We also suggest the possible applications of supercritical strings to the physical interpretation of the matrix factorization description of F-theory on singular spaces.

  5. Evidence theory and differential evolution based uncertainty quantification for buckling load of semi-rigid jointed frames

    Hesheng Tang; Yu Su; Jiao Wang

    2015-08-01

    The paper describes a procedure for the uncertainty quantification (UQ) using evidence theory in buckling analysis of semi-rigid jointed frame structures under mixed epistemic–aleatory uncertainty. The design uncertainties (geometrical, material, strength, and manufacturing) are often prevalent in engineering applications. Due to lack of knowledge or incomplete, inaccurate, unclear information in the modeling, simulation, measurement, and design, there are limitations in using only one framework (probability theory) to quantify uncertainty in a system because of the impreciseness of data or knowledge. Evidence theory provides an alternative to probability theory for the representation of epistemic uncertainty that derives from a lack of knowledge with respect to the appropriate values to use for various inputs to the model. Unfortunately, propagation of an evidence theory representation for uncertainty through a model is more computationally demanding than propagation of a probabilistic representation for uncertainty. In order to alleviate the computational difficulties in the evidence theory based UQ analysis, a differential evolution-based computational strategy for propagation of epistemic uncertainty in a system with evidence theory is presented here. A UQ analysis for the buckling load of steel-plane frames with semi-rigid connections is given herein to demonstrate accuracy and efficiency of the proposed method.

  6. On representation theory of affine Hecke algebras of type B

    Miemietz, Vanessa

    2007-01-01

    Ariki's and Grojnowski's approach to the representation theory of affine Hecke algebras of type $A$ is applied to type $B$ with unequal parameters to obtain -- under certain restrictions on the eigenvalues of the lattice operators -- analogous multiplicity-one results and a classification of irreducibles with partial branching rules as in type $A$.

  7. HPAEC-PAD quantification of Haemophilus influenzae type b polysaccharide in upstream and downstream samples.

    van der Put, Robert M F; de Haan, Alex; van den IJssel, Jan G M; Hamidi, Ahd; Beurret, Michel

    2015-11-27

    Due to the rapidly increasing introduction of Haemophilus influenzae type b (Hib) and other conjugate vaccines worldwide during the last decade, reliable and robust analytical methods are needed for the quantitative monitoring of intermediate samples generated during fermentation (upstream processing, USP) and purification (downstream processing, DSP) of polysaccharide vaccine components. This study describes the quantitative characterization of in-process control (IPC) samples generated during the fermentation and purification of the capsular polysaccharide (CPS), polyribosyl-ribitol-phosphate (PRP), derived from Hib. Reliable quantitative methods are necessary for all stages of production; otherwise accurate process monitoring and validation is not possible. Prior to the availability of high performance anion exchange chromatography methods, this polysaccharide was predominantly quantified either with immunochemical methods, or with the colorimetric orcinol method, which shows interference from fermentation medium components and reagents used during purification. Next to an improved high performance anion exchange chromatography-pulsed amperometric detection (HPAEC-PAD) method, using a modified gradient elution, both the orcinol assay and high performance size exclusion chromatography (HPSEC) analyses were evaluated. For DSP samples, it was found that the correlation between the results obtained by HPAEC-PAD specific quantification of the PRP monomeric repeat unit released by alkaline hydrolysis, and those from the orcinol method was high (R(2)=0.8762), and that it was lower between HPAEC-PAD and HPSEC results. Additionally, HPSEC analysis of USP samples yielded surprisingly comparable results to those obtained by HPAEC-PAD. In the early part of the fermentation, medium components interfered with the different types of analysis, but quantitative HPSEC data could still be obtained, although lacking the specificity of the HPAEC-PAD method. Thus, the HPAEC

  8. Decorated linear order types and the theory of concatenation

    Cacic, V.; Pudlák, P.; Restall, G.; Urquhart, A; de Visser, A.

    2010-01-01

    We study the interpretation of Grzegorczyk’s Theory of Concatenation TC in structures of decorated linear order types satisfying Grzegorczyk’s axioms. We show that TC is incomplete for this interpretation. What is more, the first order theory validated by this interpretation interprets arithmetical truth. We also show that every extension of TC has a model that is not isomorphic to a structure of decorated order types. We provide a positive result, to wit a construction that builds structures...

  9. Quantification of three-dimensional cell-mediated collagen remodeling using graph theory.

    Cemal Cagatay Bilgin

    Full Text Available BACKGROUND: Cell cooperation is a critical event during tissue development. We present the first precise metrics to quantify the interaction between mesenchymal stem cells (MSCs and extra cellular matrix (ECM. In particular, we describe cooperative collagen alignment process with respect to the spatio-temporal organization and function of mesenchymal stem cells in three dimensions. METHODOLOGY/PRINCIPAL FINDINGS: We defined two precise metrics: Collagen Alignment Index and Cell Dissatisfaction Level, for quantitatively tracking type I collagen and fibrillogenesis remodeling by mesenchymal stem cells over time. Computation of these metrics was based on graph theory and vector calculus. The cells and their three dimensional type I collagen microenvironment were modeled by three dimensional cell-graphs and collagen fiber organization was calculated from gradient vectors. With the enhancement of mesenchymal stem cell differentiation, acceleration through different phases was quantitatively demonstrated. The phases were clustered in a statistically significant manner based on collagen organization, with late phases of remodeling by untreated cells clustering strongly with early phases of remodeling by differentiating cells. The experiments were repeated three times to conclude that the metrics could successfully identify critical phases of collagen remodeling that were dependent upon cooperativity within the cell population. CONCLUSIONS/SIGNIFICANCE: Definition of early metrics that are able to predict long-term functionality by linking engineered tissue structure to function is an important step toward optimizing biomaterials for the purposes of regenerative medicine.

  10. Theory confronts experiment in the Casimir force measurements: Quantification of errors and precision

    We compare theory and experiment in the Casimir force measurement between gold surfaces performed with the atomic force microscope. Both random and systematic experimental errors are found leading to a total absolute error equal to 8.5 pN at 95% confidence. In terms of the relative errors, experimental precision of 1.75% is obtained at the shortest separation of 62 nm at 95% confidence level (at 60% confidence the experimental precision of 1% is confirmed at the shortest separation). An independent determination of the accuracies of the theoretical calculations of the Casimir force and its application to the experimental configuration is carefully made. Special attention is paid to the sample-dependent variations of the optical tabulated data due to the presence of grains, contribution of surface plasmons, and errors introduced by the use of the proximity force theorem. Nonmultiplicative and diffraction-type contributions to the surface roughness corrections are examined. The electric forces due to patch potentials resulting from the polycrystalline nature of the gold films are estimated. The finite size and thermal effects are found to be negligible. The theoretical accuracy of about 1.69% and 1.1% are found at a separation 62 nm and 200 nm, respectively. Within the limits of experimental and theoretical errors very good agreement between experiment and theory is confirmed characterized by the root-mean-square deviation of about 3.5 pN within all measurement range. The conclusion is made that the Casimir force is stable relative to variations of the sample-dependent optical and electric properties, which opens new opportunities to use the Casimir effect for diagnostic purposes

  11. Type IIB string theory, S-duality, and generalized cohomology

    Kriz, Igor [Department of Mathematics, University of Michigan, Ann Arbor, MI 48109 (United States)]. E-mail: ikriz@umich.edu; Sati, Hisham [Department of Physics, University of Adelaide, Adelaide, SA 5005 (Australia) and Department of Pure Mathematics, University of Adelaide, Adelaide, SA 5005 (Australia)]. E-mail: hsati@maths.adelaide.edu.au

    2005-05-30

    In the presence of background Neveu-Schwarz flux, the description of the Ramond-Ramond fields of type IIB string theory using twisted K-theory is not compatible with S-duality. We argue that other possible variants of twisted K-theory would still not resolve this issue. We propose instead a connection of S-duality with elliptic cohomology, and a possible T-duality relation of this to a previous proposal for IIA theory, and higher-dimensional limits. In the process, we obtain some other results which may be interesting on their own. In particular, we prove a conjecture of Witten that the 11-dimensional spin cobordism group vanishes on K(Z,6), which eliminates a potential new {theta}-angle in type IIB string theory.

  12. Quantification of poly(I:C)-mediated protection against genital herpes simplex virus type 2 infection.

    Herbst-Kralovetz, Melissa M; Pyles, Richard B

    2006-10-01

    Alternative strategies for controlling the growing herpes simplex virus type 2 (HSV-2) epidemic are needed. A novel class of immunomodulatory microbicides has shown promise as antiherpetics, including intravaginally applied CpG-containing oligodeoxynucleotides that stimulate toll-like receptor 9 (TLR9). In the current study, we quantified protection against experimental genital HSV-2 infection provided by an alternative nucleic acid-based TLR agonist, polyinosine-poly(C) (PIC) (TLR3 agonist). Using a protection quantification paradigm, groups of mice were PIC treated and then subdivided into groups challenged with escalating doses of HSV-2. Using this paradigm, a temporal window of PIC efficacy for single applications was defined as 1 day prior to (prophylactic) through 4 h after (therapeutic) viral challenge. PIC treatment within this window protected against 10-fold-higher HSV-2 challenges, as indicated by increased 50% infectious dose values relative to those for vehicle-treated controls. Disease resolution and survival were significantly enhanced by repetitive PIC doses. Using optimal PIC regimens, cytokine induction was evaluated in murine vaginal lavages and in human vaginal epithelial cells. Similar induction patterns were observed, with kinetics that explained the limited durability of PIC-afforded protection. Daily PIC delivery courses did not generate sustained cytokine levels in murine vaginal fluids that would be indicative of local immunotoxicity. No evidence of immunotoxicity was observed in selected organs that were analyzed following repetitive vaginal PIC doses. Animal and in vitro data indicate that PIC may prove to be a valuable preventative microbicide and/or therapeutic agent against genital herpes by increasing resistance to HSV-2 and enhancing disease resolution following a failure of prevention. PMID:17005677

  13. Calabi-Yau compactification of type II string theories

    Banerjee, Sibasish

    2016-01-01

    Superstring theories are the most promising theories for unified description of all fundamental interactions including gravity. However, these theories are formulated consistently only in 10 spacetime dimensions. Therefore, to connect to the observable world, it is required to compactify 6 out of those 10 dimensions in a suitable fashion. In this thesis, we mainly consider compactifications of type II string theories on Calabi-Yau threefolds. As a consequence, the resulting four dimensional theories preserve $\\mathcal{N}=2$ supersymmetry. In these cases the metrics on the moduli spaces of the matter multiplets, vector and hypermultiplets, completely determine the low energy theories. Whereas the former are very well understood by now, the complete description of hypermultiplets is more complicated. In fact, hypermultiplets receive both perturbative and non-perturbative corrections. The thesis mainly pertains to the understanding of the non-perturbative corrections. Our findings for the hypermultiplets rely on...

  14. Intensional type theory with guarded recursive types qua fixed points on universes

    Møgelberg, Rasmus Ejlers; Birkedal, Lars

    2013-01-01

    points of guarded recursive functions. Guarded recursive types can be formed simply by taking fixed points of guarded recursive functions on the universe of types. Moreover, we present a general model construction for constructing models of the intensional type theory with guarded recursive functions and...... types. When applied to the groupoid model of intensional type theory with the universe of small discrete groupoids, the construction gives a model of guarded recursion for which there is a one-to-one correspondence between fixed points of functions on the universe of types and fixed points of (suitable......Guarded recursive functions and types are useful for giving semantics to advanced programming languages and for higher-order programming with infinite data types, such as streams, e.g., for modeling reactive systems. We propose an extension of intensional type theory with rules for forming fixed...

  15. Rational sphere valued supercocycles in M-theory and type IIA string theory

    Fiorenza, Domenico; Schreiber, Urs

    2016-01-01

    We show that supercocycles on super $L_\\infty$-algebras capture, at the rational level, the twisted cohomological charge structure of the fields of M-theory and of type IIA string theory. We show that rational 4-sphere-valued supercocycles for M-branes in M-theory descend to supercocycles in type IIA string theory to yield the Ramond-Ramond fields predicted by the rational image of twisted K-theory, with the twist given by the B-field. In particular, we derive the M2/M5 $\\leftrightarrow$ F1/Dp/NS5 correspondence via dimensional reduction of sphere-valued $L_\\infty$ supercocycles in rational homotopy theory.

  16. Closed tachyon solitons in type II string theory

    Type II theories can be described as the endpoint of closed string tachyon condensation in certain orbifolds of supercritical type 0 theories. In this paper, we study solitons of this closed string tachyon and analyze the nature of the resulting defects in critical type II theories. The solitons are classified by the real K-theory groups KO of bundles associated to pairs of supercritical dimensions. For real codimension 4 and 8, corresponding to KO(S4) = Z and KO(S8) = Z, the defects correspond to a gravitational instanton and a fundamental string, respectively. We apply these ideas to reinterpret the worldsheet GLSM, regarded as a supercritical theory on the ambient toric space with closed tachyon condensation onto the CY hypersurface, and use it to describe charged solitons under discrete isometries. We also suggest the possible applications of supercritical strings to the physical interpretation of the matrix factorization description of F-theory on singular spaces. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  17. Closed tachyon solitons in type II string theory

    Garcia-Etxebarria, Inaki [Max Planck Institute for Physics, Munich (Germany); Montero, Miguel [Instituto de Fisica Teorica IFT-UAM/CSIC, C/Nicolas Cabrera 13-15, Universidad Autonoma de Madrid (Spain); Departamento de Fisica Teorica, Universidad Autonoma de Madrid (Spain); Uranga, Angel M. [Instituto de Fisica Teorica IFT-UAM/CSIC, C/Nicolas Cabrera 13-15, Universidad Autonoma de Madrid (Spain)

    2015-09-15

    Type II theories can be described as the endpoint of closed string tachyon condensation in certain orbifolds of supercritical type 0 theories. In this paper, we study solitons of this closed string tachyon and analyze the nature of the resulting defects in critical type II theories. The solitons are classified by the real K-theory groups KO of bundles associated to pairs of supercritical dimensions. For real codimension 4 and 8, corresponding to KO(S{sup 4}) = Z and KO(S{sup 8}) = Z, the defects correspond to a gravitational instanton and a fundamental string, respectively. We apply these ideas to reinterpret the worldsheet GLSM, regarded as a supercritical theory on the ambient toric space with closed tachyon condensation onto the CY hypersurface, and use it to describe charged solitons under discrete isometries. We also suggest the possible applications of supercritical strings to the physical interpretation of the matrix factorization description of F-theory on singular spaces. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  18. Module-based Hybrid Uncertainty Quantification for Multi-physics Applications: Theory and Software

    Tong, Charles [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Chen, Xiao [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Iaccarino, Gianluca [Stanford Univ., CA (United States); Mittal, Akshay [Stanford Univ., CA (United States)

    2013-10-08

    In this project we proposed to develop an innovative uncertainty quantification methodology that captures the best of the two competing approaches in UQ, namely, intrusive and non-intrusive approaches. The idea is to develop the mathematics and the associated computational framework and algorithms to facilitate the use of intrusive or non-intrusive UQ methods in different modules of a multi-physics multi-module simulation model in a way that physics code developers for different modules are shielded (as much as possible) from the chores of accounting for the uncertain ties introduced by the other modules. As the result of our research and development, we have produced a number of publications, conference presentations, and a software product.

  19. Type I/heterotic duality and M-theory amplitudes

    Green, Michael B.; Rudra, Arnab

    2016-01-01

    This paper investigates relationships between low-energy four-particle scattering amplitudes with external gauge particles and gravitons in the E_8 X E_8 and SO(32) heterotic string theories and the type I and type IA superstring theories by considering a variety of tree level and one-loop Feynman diagrams describing such amplitudes in eleven-dimensional supergravity in a Horava--Witten background compactified on a circle. This accounts for a number of perturbative and non-perturbative aspect...

  20. Non-critical type 0 string theories and their field theory duals

    In this paper we continue the study of the non-critical type 0 string and its field theory duals. We begin by reviewing some facts and conjectures about these theories. We move on to our proposal for the type 0 effective action in any dimension, its RR fields and their Chern-Simons couplings. We then focus on the case without compact dimensions and study its field theory duals. We show that one can parameterize all dual physical quantities in terms of a finite number of unknown parameters. By making some further assumptions on the tachyon couplings, one can still make some 'model independent' statements

  1. Horava—Lifshitz Type Quantum Field Theory and Hierarchy Problem

    Wei, Chao

    2016-06-01

    We study the Lifshitz type extension of the standard model (SM) at the UV, with dynamical critical exponent z = 3. One loop radiative corrections to the Higgs mass in such a model are calculated. Our result shows that, the Hierarchy problem, which has initiated many excellent extension of the minimal SM, may be weakened in the z = 3 Lifshitz type quantum field theory. Supported by the National Natural Science Foundation of China

  2. Rainich theory for type D aligned Einstein-Maxwell solutions

    Ferrando, Joan Josep; Sáez, Juan Antonio

    2007-01-01

    The original Rainich theory for the non-null Einstein-Maxwell solutions consists of a set of algebraic conditions and the Rainich (differential) equation. We show here that the subclass of type D aligned solutions can be characterized just by algebraic restrictions.

  3. Classical instanton and wormhole solutions of Type IIB string theory

    Kim, Jin Young; Lee, H. W.; Myung, Y. S.

    1996-01-01

    We study $p=-1$ D-brane in type IIB superstring theory. In addition to RR instanton, we obtain the RR charged wormhole solution in the Einstein frame. This corresponds to the ten-dimensional singular wormhole solution with infinite euclidean action.

  4. A Model of PCF in Guarded Type Theory

    Paviotti, Marco; Møgelberg, Rasmus Ejlers; Birkedal, Lars

    2015-01-01

    Guarded recursion is a form of recursion where recursive calls are guarded by delay modalities. Previous work has shown how guarded recursion is useful for constructing logics for reasoning about programming languages with advanced features, as well as for constructing and reasoning about elements...... of coinductive types. In this paper we investigate how type theory with guarded recursion can be used as a metalanguage for denotational semantics useful both for constructing models and for proving properties of these. We do this by constructing a fairly intensional model of PCF and proving it...... computationally adequate. The model construction is related to Escardo's metric model for PCF, but here everything is carried out entirely in type theory with guarded recursion, including the formulation of the operational semantics, the model construction and the proof of adequacy....

  5. A model of PCF in guarded type theory

    Paviotti, Marco; Møgelberg, Rasmus Ejlers; Birkedal, Lars

    2015-01-01

    Guarded recursion is a form of recursion where recursive calls are guarded by delay modalities. Previous work has shown how guarded recursion is useful for constructing logics for reasoning about programming languages with advanced features, as well as for constructing and reasoning about elements...... of coinductive types. In this paper we investigate how type theory with guarded recursion can be used as a metalanguage for denotational semantics useful both for constructing models and for proving properties of these. We do this by constructing a fairly intensional model of PCF and proving it...... computationally adequate. The model construction is related to Escardo's metric model for PCF, but here everything is carried out entirely in type theory with guarded recursion, including the formulation of the operational semantics, the model construction and the proof of adequacy...

  6. Inverse Regression-based Uncertainty Quantification Algorithms for High-Dimensional Models: Theory and Practice

    Li, Weixuan; Lin, Guang; Li, Bing

    2016-09-15

    A well-known challenge in uncertainty quantification (UQ) is the "curse of dimensionality". However, many high-dimensional UQ problems are essentially low-dimensional, because the randomness of the quantity of interest (QoI) is caused only by uncertain parameters varying within a low-dimensional subspace, known as the sufficient dimension reduction (SDR) subspace. Motivated by this observation, we propose and demonstrate in this paper an inverse regression-based UQ approach (IRUQ) for high-dimensional problems. Specifically, we use an inverse regression procedure to estimate the SDR subspace and then convert the original problem to a low-dimensional one, which can be efficiently solved by building a response surface model such as a polynomial chaos expansion. The novelty and advantages of the proposed approach is seen in its computational efficiency and practicality. Comparing with Monte Carlo, the traditionally preferred approach for high-dimensional UQ, IRUQ with a comparable cost generally gives much more accurate solutions even for high-dimensional problems, and even when the dimension reduction is not exactly sufficient. Theoretically, IRUQ is proved to converge twice as fast as the approach it uses seeking the SDR subspace. For example, while a sliced inverse regression method converges to the SDR subspace at the rate of $O(n^{-1/2})$, the corresponding IRUQ converges at $O(n^{-1})$. IRUQ also provides several desired conveniences in practice. It is non-intrusive, requiring only a simulator to generate realizations of the QoI, and there is no need to compute the high-dimensional gradient of the QoI. Finally, error bars can be derived for the estimation results reported by IRUQ.

  7. A ground many-valued type theory and its extensions

    Běhounek, Libor

    Linz : Johannes Kepler Universität, 2014 - (Flaminio, T.; Godo, L.; Gottwald, S.; Klement, E.). s. 15-18 [Linz Seminar on Fuzzy Set Theory /35./. 18.02.2014-22.02.2014, Linz] R&D Projects: GA MŠk ED1.1.00/02.0070 Grant ostatní: GA MŠk EE2.3.30.0010 Institutional support: RVO:67985807 Keywords : type theory * many-valued logic s * higher-order logic * teorie typů * vícehodnotové logiky * logika vyššího řádu Subject RIV: BA - General Mathematics

  8. Formation of social types in the theory of Orrin Klapp

    Trifunović Vesna

    2007-01-01

    Full Text Available Theory of Orrin Klapp about social types draws attention to important functions that these types have within certain societies as well as that it is preferable to take them into consideration if our goal is more complete knowledge of that society. For Klapp, social types are important social symbols, which in an interesting way reflect society they are part of and for that reason this author dedicates his work to considering their meanings and social functions. He thinks that we can not understand a society without the knowledge about the types with which its members are identified and which serve them as models in their social activity. Hence, these types have cognitive value since, according to Klapp, they assist in perception and "contain the truth", and therefore the knowledge of them allows easier orientation within the social system. Social types also offer insight into the scheme of the social structure, which is otherwise invisible and hidden, but certainly deserves attention if we wish clearer picture about social relations within specific community. The aim of this work is to present this very interesting and inspirative theory of Orrin Klapp, pointing out its importance but also its weaknesses which should be kept in mind during its application in further research.

  9. Type 1 2HDM as Effective Theory of Supersymmetry

    邵华

    2012-01-01

    It is generally believed that the low energy effective theory of the minimal supersymmetric standard model is the type 2 two Higgs doublet model. We will show that the type 1 two Higge doublet model can also be as the effective of supersymmetry in a specific ease with high scale supersymmetry breaking and gauge mediation. If the other electroweak doublet obtain the vacuum expectation value after the electroweak symmetry breaking, the Higgs spectrum is quite different. A remarkable feature is that the physical Higgs boson mass can be 125 GeV unlike in the ordinary models with high scale supersymmetry in which the Higgs mass is generally around 140 GeV.

  10. Multivariate Bonferroni-type inequalities theory and applications

    Chen, John

    2014-01-01

    Multivariate Bonferroni-Type Inequalities: Theory and Applications presents a systematic account of research discoveries on multivariate Bonferroni-type inequalities published in the past decade. The emergence of new bounding approaches pushes the conventional definitions of optimal inequalities and demands new insights into linear and Fréchet optimality. The book explores these advances in bounding techniques with corresponding innovative applications. It presents the method of linear programming for multivariate bounds, multivariate hybrid bounds, sub-Markovian bounds, and bounds using Hamil

  11. Type 1 2HDM as Effective Theory of Supersymmetry

    It is generally believed that the low energy effective theory of the minimal supersymmetric standard model is the type 2 two Higgs doublet model. We will show that the type 1 two Higgs doublet model can also be as the effective of supersymmetry in a specific case with high scale supersymmetry breaking and gauge mediation. If the other electroweak doublet obtain the vacuum expectation value after the electroweak symmetry breaking, the Higgs spectrum is quite different. A remarkable feature is that the physical Higgs boson mass can be 125 GeV unlike in the ordinary models with high scale supersymmetry in which the Higgs mass is generally around 140 GeV.

  12. Type I/heterotic duality and M-theory amplitudes

    Green, Michael B

    2016-01-01

    This paper investigates relationships between low-energy four-particle scattering amplitudes with external gauge particles and gravitons in the E_8 X E_8 and SO(32) heterotic string theories and the type I and type IA superstring theories by considering a variety of tree level and one-loop Feynman diagrams describing such amplitudes in eleven-dimensional supergravity in a Horava--Witten background compactified on a circle. This accounts for a number of perturbative and non-perturbative aspects of low order higher derivative terms in the low-energy expansion of string theory amplitudes, which are expected to be protected by half maximal supersymmetry from receiving corrections beyond one or two loops. It also suggests the manner in which type I/heterotic duality may be realised for certain higher derivative interactions that are not so obviously protected. For example, our considerations suggest that R**4 interactions (where R is the Riemann curvature) might receive no perturbative corrections beyond one loop ...

  13. Irregular singularities in Liouville theory and Argyres-Douglas type gauge theories, I

    Gaiotto, D. [Institute for Advanced Study (IAS), Princeton, NJ (United States); Teschner, J. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2012-03-15

    Motivated by problems arising in the study of N=2 supersymmetric gauge theories we introduce and study irregular singularities in two-dimensional conformal field theory, here Liouville theory. Irregular singularities are associated to representations of the Virasoro algebra in which a subset of the annihilation part of the algebra act diagonally. In this paper we define natural bases for the space of conformal blocks in the presence of irregular singularities, describe how to calculate their series expansions, and how such conformal blocks can be constructed by some delicate limiting procedure from ordinary conformal blocks. This leads us to a proposal for the structure functions appearing in the decomposition of physical correlation functions with irregular singularities into conformal blocks. Taken together, we get a precise prediction for the partition functions of some Argyres-Douglas type theories on S{sup 4}. (orig.)

  14. Uncertainty Propagation and Quantification using Constrained Coupled Adaptive Forward-Inverse Schemes: Theory and Applications

    Ryerson, F. J.; Ezzedine, S. M.; Antoun, T.

    2013-12-01

    equation for the distribution of k is solved, provided that Cauchy data are appropriately assigned. In the next stage, only a limited number of passive measurements are provided. In this case, the forward and inverse PDEs are solved simultaneously. This is accomplished by adding regularization terms and filtering the pressure gradients in the inverse problem. Both the forward and the inverse problem are either simultaneously or sequentially coupled and solved using implicit schemes, adaptive mesh refinement, Galerkin finite elements. The final case arises when P, k, and Q data only exist at producing wells. This exceedingly ill posed problem calls for additional constraints on the forward-inverse coupling to insure that the production rates are satisfied at the desired locations. Results from all three cases are presented demonstrating stability and accuracy of the proposed approach and, more importantly, providing some insights into the consequences of data under sampling, uncertainty propagation and quantification. We illustrate the advantages of this novel approach over the common UQ forward drivers on several subsurface energy problems in either porous or fractured or/and faulted reservoirs. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  15. Uncertainty quantification for proton-proton fusion in chiral effective field theory

    Acharya, B.; Carlsson, B. D.; Ekström, A.; Forssén, C.; Platter, L.

    2016-09-01

    We compute the S-factor of the proton-proton (pp) fusion reaction using chiral effective field theory (χEFT) up to next-to-next-to-leading order (NNLO) and perform a rigorous uncertainty analysis of the results. We quantify the uncertainties due to (i) the computational method used to compute the pp cross section in momentum space, (ii) the statistical uncertainties in the low-energy coupling constants of χEFT, (iii) the systematic uncertainty due to the χEFT cutoff, and (iv) systematic variations in the database used to calibrate the nucleon-nucleon interaction. We also examine the robustness of the polynomial extrapolation procedure, which is commonly used to extract the threshold S-factor and its energy-derivatives. By performing a statistical analysis of the polynomial fit of the energy-dependent S-factor at several different energy intervals, we eliminate a systematic uncertainty that can arise from the choice of the fit interval in our calculations. In addition, we explore the statistical correlations between the S-factor and few-nucleon observables such as the binding energies and point-proton radii of 2,3H and 3He as well as the D-state probability and quadrupole moment of 2H, and the β-decay of 3H. We find that, with the state-of-the-art optimization of the nuclear Hamiltonian, the statistical uncertainty in the threshold S-factor cannot be reduced beyond 0.7%.

  16. Uncertainty quantification for proton-proton fusion in chiral effective field theory

    Acharya, B; Ekström, A; Forssén, C; Platter, L

    2016-01-01

    We compute the $S$-factor of the proton-proton ($pp$) fusion reaction using chiral effective field theory ($\\chi$EFT) up to next-to-next-to-leading order (NNLO) and perform a rigorous uncertainty analysis of the results. We quantify the uncertainties due to (i) the computational method used to compute the $pp$ cross section in momentum space, (ii) the statistical uncertainties in the low-energy coupling constants of $\\chi$EFT, (iii) the systematic uncertainty due to the $\\chi$EFT cutoff, and (iv) systematic variations in the database used to calibrate the nucleon-nucleon interaction. We also examine the robustness of the polynomial extrapolation procedure, which is commonly used to extract the threshold $S$-factor and its energy-derivatives. By performing a statistical analysis of the polynomial fit of the energy-dependent $S$-factor at several different energy intervals, we eliminate a systematic uncertainty that can arise from the choice of the fit interval in our calculations. In addition, we explore the s...

  17. A graphical representation of Weisskopf-Wigner type theories

    It is shown that the usual (non-existing) Hamiltonian operator H' governing the interaction of a one-electron atom with transverse photons, can be written as the sum of a finite number of self-adjoint and bounded 'partial' interaction Hamiltonians L, where each L has a well defined physical meaning. The simplest of the Weisskopf-Wigner type theories are defined by a single L and practically all model Hamiltonians used in quantum optics are closely related either to a single L or to sums of very few L. The systematic 'Weisskopf-Wigner approximation scheme' introduced previously consists of special sequences of partial sums of L. The system of partial sums of L are here equipped with a system of graphs where each graph defines uniquely a certain Weisskopf-Wigner theory and visualises its physical content in a comparable way to a Feynman graph. Finally some applications are given. (author)

  18. Quantification of regional V/Q ratios in humans by use of PET. I. Theory.

    Rhodes, C G; Valind, S O; Brudin, L H; Wollmer, P E; Jones, T; Hughes, J M

    1989-04-01

    With positron emission tomography, quantitative measurements of regional alveolar and mixed venous concentrations of positron-emitting radioisotopes can be made within a transaxial section through the thorax. This allows the calculation of regional ventilation-to-perfusion (V/Q) ratios by use of established tracer dilution theory and the constant intravenous infusion of 13N. This paper considers the effect of the inspiration of dead-space gas on regional V/Q and investigates the relationship between the measured V/Q, physiological V/Q, and V/Q defined conventionally in terms of bulk gas flow (VA/Q). Ventilation has been described in terms of net gas transport, and the term effective ventilation has been introduced. A simple two-compartment model has been constructed to allow for the reinspiration of regional (or personal) and common dead-space gas. By use of this model, with parameters representative of normal lung the effective V/Q ratio for 13N [(VA/Q)eff(13N)] is shown to overestimate VA/Q by 18% when VA/Q = 0.1 but underestimate VA/Q by 68% when VA/Q = 10. For physiological gases, the model predicts that the behavior of O2 should be similar to that of 13N, so that, in terms of gas transport, V/Q ratios obtained using the infusion of 13N closely follow those for O2. Values of the effective V/Q ratio for CO2 [(VA/Q)eff(CO2)] lie approximately halfway between (VA/Q)eff(13N) and VA/Q. These results indicate that dead-space ventilation is far less a confounding issue when V/Q is considered in terms of net gas transport (VAeff), rather than bulk flow (VA).(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2786522

  19. Type II Superstring Field Theory: Geometric Approach and Operadic Description

    Jurco, Branislav

    2013-01-01

    We outline the construction of type II superstring field theory leading to a geometric and algebraic BV master equation, analogous to Zwiebach's construction for the bosonic string. The construction uses the small Hilbert space. Elementary vertices of the non-polynomial action are described with the help of a properly formulated minimal area problem. They give rise to an infinite tower of superstring field products defining a $\\mathcal{N}=1$ generalization of a loop homotopy Lie algebra, the genus zero part generalizing a homotopy Lie algebra. Finally, we give an operadic interpretation of the construction.

  20. Type II superstring field theory: geometric approach and operadic description

    Jurčo, Branislav; Münster, Korbinian

    2013-04-01

    We outline the construction of type II superstring field theory leading to a geometric and algebraic BV master equation, analogous to Zwiebach's construction for the bosonic string. The construction uses the small Hilbert space. Elementary vertices of the non-polynomial action are described with the help of a properly formulated minimal area problem. They give rise to an infinite tower of superstring field products defining a {N} = 1 generalization of a loop homotopy Lie algebra, the genus zero part generalizing a homotopy Lie algebra. Finally, we give an operadic interpretation of the construction.

  1. Aspects of moduli stabilization in type IIB string theory

    Shaaban Khalil; Ahmad Moursy; Ali Nassar

    2015-01-01

    We review moduli stabilization in type IIB string theory compactification with fluxes. We focus on KKLT and Large Volume Scenario (LVS). We show that the predicted soft SUSY breaking terms in KKLT model are not phenomenological viable. In LVS, the following result for scalar mass, gaugino mass, and trilinear term is obtained: m0=m1/2=-A0=m3/2 , which may account for Higgs mass limit if m3/2~O(1.5)  TeV. However, in this case, the relic abundance of the lightest neutralino cannot be consistent...

  2. Classical Bianchi Type I Cosmology in K-Essence Theory

    2014-01-01

    We use one of the simplest forms of the K-essence theory and we apply it to the classical anisotropic Bianchi type I cosmological model, with a barotropic perfect fluid ( p=γρ ) modeling the usual matter content and with cosmological constant Λ . Classical exact solutions for any γ≠1 and Λ=0 are found in closed form, whereas solutions for Λ≠0 are found for particular values in the barotropic parameter. We present the possible isotropization of the cosmological model Bianchi I using the ratio ...

  3. Church-style type theories over finitary weakly implicative logics

    Běhounek, Libor

    Vienna: Vienna University of Technology, 2014 - (Baaz, M.; Ciabattoni, A.; Hetzl, S.). s. 131-133 [LATD 2014. Logic, Algebra and Truth Degrees. 16.07.2014-19.07.2014, Vienna] R&D Projects: GA MŠk ED1.1.00/02.0070 Grant ostatní: GA MŠk EE2.3.30.0010 Institutional support: RVO:67985807 Keywords : type theory * higher-order logic * weakly implicative logics * teorie typů * logika vyššího řádu * slabě implikační logiky Subject RIV: BA - General Mathematics

  4. String scattering from D-branes in type 0 theories

    We derive fully covariant expressions for all two-point scattering amplitudes involving a closed string tachyon and massless strings from the Dirichlet brane in type 0 theories. The amplitude for two massless D-brane fluctuations to produce a closed string tachyon is also evaluated. We then examine in detail these string scattering amplitudes in order to extract world-volume couplings of the tachyon with itself and with massless fields on a D-brane. We find that the tachyon appears as an overall coupling function in the Born-Infeld action and conjecture the form of the function

  5. Radiochemical Separation and Quantification of Tritium in Metallic Radwastes Generated from CANDU Type NPP - 13279

    Ahn, H.J.; Choi, K.C.; Choi, K.S.; Park, T.H.; Park, Y.J.; Song, K. [Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon, 305-330 (Korea, Republic of)

    2013-07-01

    As a destructive quantification method of {sup 3}H in low and intermediate level radwastes, bomb oxidation, sample oxidation, and wet oxidation methods have been introduced. These methods have some merits and demerits in the radiochemical separation of {sup 3}H radionuclides. That is, since the bomb oxidation and sample oxidation methods are techniques using heating at high temperature, the separation methods of the radionuclides are relatively simple. However, since {sup 3}H radionuclide has a property of being diffused deeply into the inside of metals, {sup 3}H which is distributed on the surface of the metals can only be extracted if the methods are applied. As an another separation method, the wet oxidation method makes {sup 3}H oxidized with an acidic solution, and extracted completely to an oxidized HTO compound. However, incomplete oxidized {sup 3}H compounds, which are produced by reactions of acidic solutions and metallic radwastes, can be released into the air. Thus, in this study, a wet oxidation method to extract and quantify the {sup 3}H radionuclide from metallic radwastes was established. In particular, a complete extraction method and complete oxidation method of incomplete chemical compounds of {sup 3}H using a Pt catalyst were studied. The radioactivity of {sup 3}H in metallic radwastes is extracted and measured using a wet oxidation method and liquid scintillation counter. Considering the surface dose rate of the sample, the appropriate size of the sample was determined and weighed, and a mixture of oxidants was added to a 200 ml round flask with 3 tubes. The flask was quickly connected to the distilling apparatus. 20 mL of 16 wt% H{sub 2}SO{sub 4} was given into the 200-ml round flask through a dropping funnel while under stirring and refluxing. After dropping, the temperature of the mixture was raised to 96 deg. C and the sample was leached and oxidized by refluxing for 3 hours. At that time, the incomplete oxidized {sup 3}H compounds were

  6. Development of Primer-Probe Energy Transfer real-time PCR for the detection and quantification of porcine circovirus type 2

    Balint, Adam; Tenk, Miklós; Deim, Zoltán;

    2009-01-01

    A real-time PCR assay, based on Primer-Probe Energy Transfer (PriProET), was developed to improve the detection and quantification of porcine circovirus type 2 (PVC2). PCV2 is recognised as the essential infectious agent in post-weaning multisystemic wasting syndrome (PMWS) and has been associated...

  7. In situ fluid typing and quantification with 1D and 2D NMR logging.

    Sun, Boqin

    2007-05-01

    In situ nuclear magnetic resonance (NMR) fluid typing has recently gained momentum due to data acquisition and inversion algorithm enhancement of NMR logging tools. T(2) distributions derived from NMR logging contain information on bulk fluids and pore size distributions. However, the accuracy of fluid typing is greatly overshadowed by the overlap between T(2) peaks arising from different fluids with similar apparent T(2) relaxation times. Nevertheless, the shapes of T(2) distributions from different fluid components are often different and can be predetermined. Inversion with predetermined T(2) distributions allows us to perform fluid component decomposition to yield individual fluid volume ratios. Another effective method for in situ fluid typing is two-dimensional (2D) NMR logging, which results in proton population distribution as a function of T(2) relaxation time and fluid diffusion coefficient (or T(1) relaxation time). Since diffusion coefficients (or T(1) relaxation time) for different fluid components can be very different, it is relatively easy to separate oil (especially heavy oil) from water signal in a 2D NMR map and to perform accurate fluid typing. Combining NMR logging with resistivity and/or neutron/density logs provides a third method for in situ fluid typing. We shall describe these techniques with field examples. PMID:17466778

  8. Type II fuzzy systems for amyloid plaque segmentation in transgenic mouse brains for Alzheimer's disease quantification

    Khademi, April; Hosseinzadeh, Danoush

    2014-03-01

    Alzheimer's disease (AD) is the most common form of dementia in the elderly characterized by extracellular deposition of amyloid plaques (AP). Using animal models, AP loads have been manually measured from histological specimens to understand disease etiology, as well as response to treatment. Due to the manual nature of these approaches, obtaining the AP load is labourious, subjective and error prone. Automated algorithms can be designed to alleviate these challenges by objectively segmenting AP. In this paper, we focus on the development of a novel algorithm for AP segmentation based on robust preprocessing and a Type II fuzzy system. Type II fuzzy systems are much more advantageous over the traditional Type I fuzzy systems, since ambiguity in the membership function may be modeled and exploited to generate excellent segmentation results. The ambiguity in the membership function is defined as an adaptively changing parameter that is tuned based on the local contrast characteristics of the image. Using transgenic mouse brains with AP ground truth, validation studies were carried out showing a high degree of overlap and low degree of oversegmentation (0.8233 and 0.0917, respectively). The results highlight that such a framework is able to handle plaques of various types (diffuse, punctate), plaques with varying Aβ concentrations as well as intensity variation caused by treatment effects or staining variability.

  9. Quantification and monosaccharide composition of hemicelluloses from different plant functional types.

    Schädel, Christina; Blöchl, Andreas; Richter, Andreas; Hoch, Günter

    2010-01-01

    Hemicelluloses are the second most abundant polysaccharide in nature after cellulose. So far, the chemical heterogeneity of cell-wall hemicelluloses and the relatively large sample-volume required in existing methods represent major obstacles for large-scale, cross-species analyses of this important plant compound. Here, we apply a new micro-extraction method to analyse hemicelluloses and the ratio of 'cellulose and lignin' to hemicelluloses in different tissues of 28 plant species comprising four plant functional types (broad-leaved trees, conifers, grasses and herbs). For this study, the fiber analysis after Van Soest was modified to enable the simultaneous quantitative and qualitative measurements of hemicelluloses in small sample volumes. Total hemicellulose concentrations differed markedly among functional types and tissues with highest concentration in sapwood of broad-leaved trees (31% d.m. in Fraxinus excelsior) and lowest concentration between 10 and 15% d.m. in leaves and bark of woody species as well as in roots of herbs. As for total hemicellulose concentrations, plant functional types and tissues exhibited characteristic ratios between the sum of cellulose plus lignin and hemicelluloses, with very high ratios (>4) in bark of trees and low ratios (plant functional types which exhibited characteristic hemicellulose concentrations and monosaccharide patterns. PMID:19926487

  10. Aspects of Moduli Stabilization in Type IIB String Theory

    Shaaban Khalil

    2016-01-01

    Full Text Available We review moduli stabilization in type IIB string theory compactification with fluxes. We focus on KKLT and Large Volume Scenario (LVS. We show that the predicted soft SUSY breaking terms in KKLT model are not phenomenological viable. In LVS, the following result for scalar mass, gaugino mass, and trilinear term is obtained: m0=m1/2=-A0=m3/2, which may account for Higgs mass limit if m3/2~O(1.5 TeV. However, in this case, the relic abundance of the lightest neutralino cannot be consistent with the measured limits. We also study the cosmological consequences of moduli stabilization in both models. In particular, the associated inflation models such as racetrack inflation and Kähler inflation are analyzed. Finally, the problem of moduli destabilization and the effect of string moduli backreaction on the inflation models are discussed.

  11. Type I non-abelian superconductors in supersymmetric gauge theories

    Non-BPS non-Abelian vortices with CP1 internal moduli space are studied in an N = 2 supersymmetric U(1) x SU(2) gauge theory with adjoint mass terms. For generic internal orientations the classical force between two vortices can be attractive or repulsive. On the other hand, the mass of the scalars in the theory is always less than that of the vector bosons; also, the force between two vortices with the same CP1 orientation is always attractive: for these reasons we interpret our model as a non-Abelian generalization of type I superconductors. We compute the effective potential in the limit of two well separated vortices. It is a function of the distance and of the relative colour-flavour orientation of the two vortices; in this limit we find an effective description in terms of two interacting CP1 sigma models. In the limit of two coincident vortices we find two different solutions with the same topological winding and, for generic values of the parameters, different tensions. One of the two solutions is described by a CP1 effective sigma model, while the other is just an Abelian vortex without internal degrees of freedom. For generic values of the parameters, one of the two solutions is metastable, while there are evidences that the other one is truly stable

  12. Quantification of Poly(I:C)-Mediated Protection against Genital Herpes Simplex Virus Type 2 Infection

    Herbst-Kralovetz, Melissa M.; Pyles, Richard B.

    2006-01-01

    Alternative strategies for controlling the growing herpes simplex virus type 2 (HSV-2) epidemic are needed. A novel class of immunomodulatory microbicides has shown promise as antiherpetics, including intravaginally applied CpG-containing oligodeoxynucleotides that stimulate toll-like receptor 9 (TLR9). In the current study, we quantified protection against experimental genital HSV-2 infection provided by an alternative nucleic acid-based TLR agonist, polyinosine-poly(C) (PIC) (TLR3 agonist)....

  13. Quantification and odor contribution of 2-furanmethanethiol in different types of fermented soybean paste miso.

    Ohata, Motoko; Tominaga, Takatoshi; Dubourdieu, Denis; Kubota, Kikue; Sugawara, Etsuko

    2009-03-25

    2-Furanmethanethiol, a compound contained in many kinds of food, was identified for the first time in five types of miso fermented soybean paste (red salty rice miso, thin-colored salty rice miso, weak salty rice miso, barley miso, and soy miso) by specific extraction of volatile thiols using p-hydroxymercuribenzoate. In the triangle test with red salty rice miso, which included a higher concentration of 2-furanmethanethiol, and thin-colored salty rice miso, which included a lower concentration of 2-furanmethanethiol, it was shown that the aroma of thin-colored salty rice miso was similar to that of red salty rice miso by adding 2-furanmethanethiol into thin-colored salty rice miso. In addition, a quantitative descriptive analysis (QDA) clearly shows that 2-furanmethanethiol contributed to the intensity of three odor qualities "thick, complex", "sweet", and "pleasant aroma like coffee beans" in six odor qualities and was a very important component of miso aroma. PMID:19231859

  14. Comparison between magnetic force microscopy and electron back-scatter diffraction for ferrite quantification in type 321 stainless steel

    Several analytical techniques that are currently available can be used to determine the spatial distribution and amount of austenite, ferrite and precipitate phases in steels. The application of magnetic force microscopy, in particular, to study the local microstructure of stainless steels is beneficial due to the selectivity of this technique for detection of ferromagnetic phases. In the comparison of Magnetic Force Microscopy and Electron Back-Scatter Diffraction for the morphological mapping and quantification of ferrite, the degree of sub-surface measurement has been found to be critical. Through the use of surface shielding, it has been possible to show that Magnetic Force Microscopy has a measurement depth of 105–140 nm. A comparison of the two techniques together with the depth of measurement capabilities are discussed. - Highlights: • MFM used to map distribution and quantify ferrite in type 321 stainless steels. • MFM results compared with EBSD for same region, showing good spatial correlation. • MFM gives higher area fraction of ferrite than EBSD due to sub-surface measurement. • From controlled experiments MFM depth sensitivity measured from 105 to 140 nm. • A correction factor to calculate area fraction from MFM data is estimated

  15. In vivo quantification of brain injury in adult Niemann-Pick Disease Type C.

    Zaaraoui, Wafaa; Crespy, Lydie; Rico, Audrey; Faivre, Anthony; Soulier, Elisabeth; Confort-Gouny, Sylviane; Cozzone, Patrick J; Pelletier, Jean; Ranjeva, Jean-Philippe; Kaphan, Elsa; Audoin, Bertrand

    2011-06-01

    Development of surrogate markers is necessary to assess the potential efficacy of new therapeutics in Niemann-Pick Disease Type C (NP-C). In the present study, magnetization transfer ratio (MTR) imaging, a quantitative MRI imaging technique sensitive to subtle brain microstructural changes, was applied in two patients suffering from adult NP-C. Statistical mapping analysis was performed to compare each patient's MTR maps with those of a group of 34 healthy controls to quantify and localize the extent of brain injury of each patient. Using this method, pathological changes were evidenced in the cerebellum, the thalami and the lenticular nuclei in both patients and also in the fronto-temporal cortices in the patient with the worse functional deficit. In addition, white matter changes were located in the midbrain, the cerebellum and the fronto-temporal lobes in the patient with the higher level of disability and in only one limited periventricular white matter region in the other patient. A 6-month follow-up was performed in the patient with the lower functional deficit and evidenced significant extension of grey matter (GM) and white matter (WM) injuries during the following period (14% of increased injury for GM and 53% for WM). This study demonstrates that significant brain injury related to clinical deficit can be assessed in vivo in adult NP-C using MTR imaging. Although preliminary, these findings suggest that MTR imaging may be a relevant candidate for the development of biomarker in NP-C. PMID:21397539

  16. Quantification of the host response proteome after herpes simplex virus type 1 infection.

    Berard, Alicia R; Coombs, Kevin M; Severini, Alberto

    2015-05-01

    Viruses employ numerous host cell metabolic functions to propagate and manage to evade the host immune system. For herpes simplex virus type 1 (HSV1), a virus that has evolved to efficiently infect humans without seriously harming the host in most cases, the virus-host interaction is specifically interesting. This interaction can be best characterized by studying the proteomic changes that occur in the host during infection. Previous studies have been successful at identifying numerous host proteins that play important roles in HSV infection; however, there is still much that we do not know. This study identifies host metabolic functions and proteins that play roles in HSV infection, using global quantitative stable isotope labeling by amino acids in cell culture (SILAC) proteomic profiling of the host cell combined with LC-MS/MS. We showed differential proteins during early, mid and late infection, using both cytosolic and nuclear fractions. We identified hundreds of differentially regulated proteins involved in fundamental cellular functions, including gene expression, DNA replication, inflammatory response, cell movement, cell death, and RNA post-transcriptional modification. Novel differentially regulated proteins in HSV infections include some previously identified in other virus systems, as well as fusion protein, involved in malignant liposarcoma (FUS) and hypoxia up-regulated 1 protein precursor (HYOU1), which have not been identified previously in any virus infection. PMID:25815715

  17. Type IIA flux compactifications. Vacua, effective theories and cosmological challenges

    Koers, Simon

    2009-07-30

    In this thesis, we studied a number of type IIA SU(3)-structure compactifications with 06-planes on nilmanifolds and cosets, which are tractable enough to allow for an explicit derivation of the low energy effective theory. In particular we calculated the mass spectrum of the light scalar modes, using N = 1 supergravity techniques. For the torus and the Iwasawa solution, we have also performed an explicit Kaluza-Klein reduction, which led to the same result. For the nilmanifold examples we have found that there are always three unstabilized moduli corresponding to axions in the RR sector. On the other hand, in the coset models, except for SU(2) x SU(2), all moduli are stabilized. We discussed the Kaluza-Klein decoupling for the supersymmetric AdS vacua and found that it requires going to the Nearly-Calabi Yau limited. We searched for non-trivial de Sitter minima in the original flux potential away from the AdS vacuum. Finally, in chapter 7, we focused on a family of three coset spaces and constructed non-supersymmetric vacua on them. (orig.)

  18. Type IIA flux compactifications. Vacua, effective theories and cosmological challenges

    In this thesis, we studied a number of type IIA SU(3)-structure compactifications with 06-planes on nilmanifolds and cosets, which are tractable enough to allow for an explicit derivation of the low energy effective theory. In particular we calculated the mass spectrum of the light scalar modes, using N = 1 supergravity techniques. For the torus and the Iwasawa solution, we have also performed an explicit Kaluza-Klein reduction, which led to the same result. For the nilmanifold examples we have found that there are always three unstabilized moduli corresponding to axions in the RR sector. On the other hand, in the coset models, except for SU(2) x SU(2), all moduli are stabilized. We discussed the Kaluza-Klein decoupling for the supersymmetric AdS vacua and found that it requires going to the Nearly-Calabi Yau limited. We searched for non-trivial de Sitter minima in the original flux potential away from the AdS vacuum. Finally, in chapter 7, we focused on a family of three coset spaces and constructed non-supersymmetric vacua on them. (orig.)

  19. Three Types of Cooling Superfluid Neutron Stars Theory and Observations

    Kaminker, A D; Gnedin, O Y

    2002-01-01

    Cooling of neutron stars (NSs) with the cores composed of neutrons, protons, and electrons is simulated assuming $^1$S$_0$ pairing of neutrons in the NS crust, and also $^1$S$_0$ pairing of protons and weak $^3$P$_2$ pairing of neutrons in the NS core, and using realistic density profiles of the superfluid critical temperatures $T_{\\rm c}(\\rho)$. The theoretical cooling models of isolated middle-aged NSs can be divided into three main types. (I) {\\it Low-mass}, {\\it slowly cooling} NSs where the direct Urca process of neutrino emission is either forbidden or almost fully suppressed by the proton superfluidity. (II) {\\it Medium-mass} NSs which show {\\it moderate} cooling via the direct Urca process suppressed by the proton superfluidity. (III) {\\it Massive} NSs which show {\\it fast} cooling via the direct Urca process weakly suppressed by superfluidity. Confronting the theory with observations we treat RX J0822--43, PSR 1055--52 and RX J1856--3754 as slowly cooling NSs. To explain these sufficiently warm sourc...

  20. Type-Token Dichotomy in the Identity Theory of Mind

    Nath, Dr. Shanjendu

    2014-01-01

    Identity theory of mind occupies an important place in the history of philosophy of mind. According to his theory mental events are nothing but physical events in the brain. This theory came into existence as a reaction of behaviourism and developed by U. T. Place, J. J. C. Smart, H. Feigl and others. But there is a debate among the profounder of the theory and this is- whether it is said about concrete particulars, (e.g., individual instances of occurring in particular subject at particular ...

  1. Rotational Invariance in the M(atrix) Formulation of Type IIB Theory

    Sethi, S K; Sethi, Savdeep; Susskind, Leonard

    1997-01-01

    The matrix model formulation of M-theory can be generalized by compactification to ten-dimensional type II string theory, formulated in the infinite momentum frame. Both the type IIA and IIB string theories can be formulated in this way. In the M-theory and type IIA cases, the transverse rotational invariance is manifest, but in the IIB case, one of the transverse dimensions materializes in a completely different way from the other seven. The full O(8) rotational symmetry then follows in a surprising way from the electric-magnetic duality of supersymmetric Yang-Mills field theory.

  2. Development and validation of an enzyme-linked immunosorbent assay for the quantification of a specific MMP-9 mediated degradation fragment of type III collagen--A novel biomarker of atherosclerotic plaque remodeling

    Barascuk, Natasha; Vassiliadis, Efstathios; Larsen, Lise;

    2011-01-01

    Degradation of collagen in the arterial wall by matrix metalloproteinases is the hallmark of atherosclerosis. We have developed an ELISA for the quantification of type III collagen degradation mediated by MMP-9 in urine....

  3. Krichever-Novikov type algebras theory and applications

    Schlichenmaier, Martin

    2014-01-01

    Krichever and Novikov introduced certain classes of infinite dimensionalLie algebrasto extend the Virasoro algebra and its related algebras to Riemann surfaces of higher genus. The author of this book generalized and extended them toa more general setting needed by the applications. Examples of applications are Conformal Field Theory, Wess-Zumino-Novikov-Witten models, moduli space problems, integrable systems, Lax operator algebras, and deformation theory of Lie algebra. Furthermore they constitute an important class of infinite dimensional Lie algebras which due to their geometric origin are

  4. Initial layer theory and model equations of Volterra type

    It is demonstrated here that there exist initial layers to singularly perturbed Volterra equations whose thicknesses are not of order of magnitude of 0(ε), ε → 0. It is also shown that the initial layer theory is extremely useful because it allows one to construct the approximate solution to an equation, which is almost identical to the exact solution. (author)

  5. A phenomenological Landauer-type theory on colossal magnetoresistance

    Ding, M.; Tian, G.-S.; Lin, T.-H.

    1996-12-01

    A two-dimensional interacting magnetic domains model is examined to explain the colossal magnetoresistance (CMR) recently observed in manganese-oxides. Electrons transport properties were studied by using Landauer's multichannel transport theory and recursive Green's function technique. Colossal magnetoresistance shows up in this system. The temperature dependence of system's MR is also studied.

  6. Quantification of genetically modified soybeans using a combination of a capillary-type real-time PCR system and a plasmid reference standard.

    Toyota, Akie; Akiyama, Hiroshi; Sugimura, Mitsunori; Watanabe, Takahiro; Kikuchi, Hiroyuki; Kanamori, Hisayuki; Hino, Akihiro; Esaka, Muneharu; Maitani, Tamio

    2006-04-01

    Because the labeling of grains and feed- and foodstuffs is mandatory if the genetically modified organism (GMO) content exceeds a certain level of approved genetically modified varieties in many countries, there is a need for a rapid and useful method of GMO quantification in food samples. In this study, a rapid detection system was developed for Roundup Ready Soybean (RRS) quantification using a combination of a capillary-type real-time PCR system, a LightCycler real-time PCR system, and plasmid DNA as the reference standard. In addition, we showed for the first time that the plasmid and genomic DNA should be similar in the established detection system because the PCR efficiencies of using plasmid DNA and using genomic DNA were not significantly different. The conversion factor (Cf) to calculate RRS content (%) was further determined from the average value analyzed in three laboratories. The accuracy and reproducibility of this system for RRS quantification at a level of 5.0% were within a range from 4.46 to 5.07% for RRS content and within a range from 2.0% to 7.0% for the relative standard deviation (RSD) value, respectively. This system rapidly monitored the labeling system and had allowable levels of accuracy and precision. PMID:16636447

  7. MASLOV-TYPE INDEX THEORY FOR SYMPLECTIC PATHS AND SPECTRAL FLOW(Ⅱ)

    2000-01-01

    Based on the spectral flow and the stratification structures of the symplectic group Sp(2n, C),the Maslov-type index theory and its generalization, the w-index theory parameterized by all w on the unit circle, for arbitrary paths in Sp(2n, C) are established. Then the Bott-type iteration formula of the Maslov-type indices for iterated paths in Sp(2n, C) is proved, and the mean index for any path in Sp(2n, C) is defined. Also, the relation among various Maslov-type index theories is studied.

  8. Conformal field theory and functions of hypergeometric type

    Conformal field theory provides a universal description of various phenomena in natural sciences. Its development, swift and successful, belongs to the major highlights of theoretical physics of the late XX century. In contrast, advances of the theory of hypergeometric functions always assumed a slower pace throughout the centuries of its existence. Functional identities studied by this mathematical discipline are fascinating both in their complexity and beauty. This thesis investigates the interrelation of two subjects through a direct analysis of three CFT problems: two-point functions of the 2d strange metal CFT, three-point functions of primaries of the non-rational Toda CFT and kinematical parts of Mellin amplitudes for scalar four-point functions in general dimensions. We flash out various generalizations of hypergeometric functions as a natural mathematical language for two of these problems. Several new methods inspired by extensions of classical results on hypergeometric functions, are presented.

  9. Conformal field theory and functions of hypergeometric type

    Isachenkov, Mikhail

    2016-03-15

    Conformal field theory provides a universal description of various phenomena in natural sciences. Its development, swift and successful, belongs to the major highlights of theoretical physics of the late XX century. In contrast, advances of the theory of hypergeometric functions always assumed a slower pace throughout the centuries of its existence. Functional identities studied by this mathematical discipline are fascinating both in their complexity and beauty. This thesis investigates the interrelation of two subjects through a direct analysis of three CFT problems: two-point functions of the 2d strange metal CFT, three-point functions of primaries of the non-rational Toda CFT and kinematical parts of Mellin amplitudes for scalar four-point functions in general dimensions. We flash out various generalizations of hypergeometric functions as a natural mathematical language for two of these problems. Several new methods inspired by extensions of classical results on hypergeometric functions, are presented.

  10. Quantification of the N-terminal propeptide of human procollagen type I (PINP): comparison of ELISA and RIA with respect to different molecular forms

    Jensen, Charlotte Harken; Hansen, M; Brandt, J;

    1998-01-01

    This paper compares the results of procollagen type I N-terminal propeptide (PINP) quantification by radioimmunoassay (RIA) and enzyme linked immunosorbent assay (ELISA). PINP in serum from a patient with uremic hyperparathyroidism was measured in RIA and ELISA to 20 micrograms l-1 and 116...... micrograms l-1 and the corresponding concentrations in dialysis fluid were 94.5 micrograms l-1 and 140 micrograms l-1, respectively. PINP antigen appears in two distinct peaks following size chromatography and the two peak fractions display immunological identity and identical M(r)'s (27 kDa: SDS...

  11. Rapid Quantification of Melamine in Different Brands/Types of Milk Powders Using Standard Addition Net Analyte Signal and Near-Infrared Spectroscopy.

    Tang, Bang-Cheng; Cai, Chen-Bo; Shi, Wei; Xu, Lu

    2016-01-01

    Multivariate calibration (MVC) and near-infrared (NIR) spectroscopy have demonstrated potential for rapid analysis of melamine in various dairy products. However, the practical application of ordinary MVC can be largely restricted because the prediction of a new sample from an uncalibrated batch would be subject to a significant bias due to matrix effect. In this study, the feasibility of using NIR spectroscopy and the standard addition (SA) net analyte signal (NAS) method (SANAS) for rapid quantification of melamine in different brands/types of milk powders was investigated. In SANAS, the NAS vector of melamine in an unknown sample as well as in a series of samples added with melamine standards was calculated and then the Euclidean norms of series standards were used to build a straightforward univariate regression model. The analysis results of 10 different brands/types of milk powders with melamine levels 0~0.12% (w/w) indicate that SANAS obtained accurate results with the root mean squared error of prediction (RMSEP) values ranging from 0.0012 to 0.0029. An additional advantage of NAS is to visualize and control the possible unwanted variations during standard addition. The proposed method will provide a practically useful tool for rapid and nondestructive quantification of melamine in different brands/types of milk powders. PMID:27525154

  12. Surveying problem solution with theory and objective type questions

    Chandra, AM

    2005-01-01

    The book provides a lucid and step-by-step treatment of the various principles and methods for solving problems in land surveying. Each chapter starts with basic concepts and definitions, then solution of typical field problems and ends with objective type questions. The book explains errors in survey measurements and their propagation. Survey measurements are detailed next. These include horizontal and vertical distance, slope, elevation, angle, and direction. Measurement using stadia tacheometry and EDM are then highlighted, followed by various types of levelling problems. Traversing is then explained, followed by a detailed discussion on adjustment of survey observations and then triangulation and trilateration.

  13. On the theory of supernova type Ia explosion.

    Liberman, M. A.

    2000-03-01

    A self-consistent model of a white dwarf burning in supernova Ia events is presented which includes the consequent stages of the flame, the spontaneous explosion and the detonation. The spontaneous explosion triggers the detonation, which incinerates the rest of the pre-expanded star. The expansion of the white dwarf during the flame stage of burning leads to the production of intermediate mass elements (S, Si, Ca etc.) in agreement with the observed spectrum. Stability analysis of the thermonuclear detonation in a white dwarf shows that the detonation is unstable and self-quenching at high densities of the degenerate matter ρ > 2.1·107 g/cm3 and it becomes stable at lower densities. The detonation overcomes gravitational binding and causes mass ejection. The proposed theory provides the physical basis for the explanation of the observed spectrum of supernovae Ia.

  14. Symmetry breaking and restoration in Lifshitz type theories

    Farakos, K., E-mail: kfarakos@central.ntua.gr [Department of Physics, National Technical University of Athens, Zografou Campus, 15780 Athens (Greece); Metaxas, D., E-mail: metaxas@central.ntua.gr [Department of Physics, National Technical University of Athens, Zografou Campus, 15780 Athens (Greece)

    2012-02-07

    We consider the one-loop effective potential at zero and finite temperature in scalar field theories with anisotropic space-time scaling. For z=2, there is a symmetry breaking term induced at one loop at zero temperature and we find symmetry restoration through a first-order phase transition at high temperature. For z=3, we considered at first the case with a positive mass term at tree level and found no symmetry breaking effects induced at one loop, and then we study the case with a negative mass term at tree level where we cannot conclude about symmetry restoration effects at high temperature because of the imaginary parts that appear in the effective potential for small values of the scalar field.

  15. Symmetry breaking and restoration in Lifshitz type theories

    Farakos, K.; Metaxas, D.

    2012-02-01

    We consider the one-loop effective potential at zero and finite temperature in scalar field theories with anisotropic space-time scaling. For z = 2, there is a symmetry breaking term induced at one loop at zero temperature and we find symmetry restoration through a first-order phase transition at high temperature. For z = 3, we considered at first the case with a positive mass term at tree level and found no symmetry breaking effects induced at one loop, and then we study the case with a negative mass term at tree level where we cannot conclude about symmetry restoration effects at high temperature because of the imaginary parts that appear in the effective potential for small values of the scalar field.

  16. Symmetry breaking and restoration in Lifshitz type theories

    Farakos, K

    2011-01-01

    We consider the one-loop effective potential at zero and finite temperature in scalar field theories with anisotropic space-time scaling. For $z=2$, there is a symmetry breaking term induced at one-loop at zero temperature and we find symmetry restoration through a first-order phase transition at high temperature. For $z=3$, we considered at first the case with a positive mass term at tree level and found no symmetry breaking effects induced at one-loop, and then we study the case with a negative mass term at tree level where we cannot conclude about symmetry restoration effects at high temperature because of the imaginary parts that appear in the effective potential for small values of the scalar field.

  17. Cosmic web-type classification using decision theory

    Leclercq, Florent; Wandelt, Benjamin

    2015-01-01

    We propose a decision criterion for segmenting the cosmic web into different structure types (voids, sheets, filaments and clusters) on the basis of their respective probabilities and the strength of data constraints. Our approach is inspired by an analysis of games of chance where the gambler only plays if a positive expected net gain can be achieved based on some degree of privileged information. The result is a general solution for classification problems in the face of uncertainty, including the option of not committing to a class for a candidate object. As an illustration, we produce high-resolution maps of web-type constituents in the nearby Universe as probed by the Sloan Digital Sky Survey main galaxy sample. Other possible applications include the selection and labeling of objects in catalogs derived from astronomical survey data.

  18. Improved real-time PCR assay for detection and quantification of all 54 known types of human adenoviruses in clinical samples

    Bil-Lula, Iwona; De Franceschi, Nicola; Pawlik, Krzysztof; WoŸniak, Mieczysław

    2012-01-01

    Summary Background Detection and quantification of adenoviruses (AdVs) causing life-threatening complications are important abilities in recognition of infection and management of immunocompromised patients. Due to the rapid increase in the number of known AdV types, most commercial tests for detection and identification of AdVs are outdated. Material/Methods We designed an improved, easier and faster real-time quantitative polymerase chain reaction (RQ-PCR) method for detection and quantification of 54 types of human AdVs. A wide validation effort was undertaken to ensure confidence in highly sensitive and specific detection of AdVs in compromised patients. The validation process included evaluation of the method’s suitability and reliability for use in routine diagnostics. Results Due to high sensitivity (9.2×102 copies/ml) and broad dynamic range (7 log) we are able to detect specific viral DNA in large amounts of cell-free body fluids. The new assay is characterized by high precision and low variation within and between individual virus tests (CV=0.036%, CV=1.29%), low bias error (4%) and no cross-reactivity with other pathogens. Conclusions The implementation of this new assay in clinical and laboratory practice provides a rapid, reliable and less laborious method for detection and monitoring of AdV replication in immunocompromised patients. Moreover, it offers the ability to distinguish between active and latent infection and assess treatment efficiency. PMID:22648243

  19. Energy of the Universe in Bianchi-type I Models in Moller's Tetrad Theory of Gravity

    Aydogdu, Oktay; Salti, Mustafa

    2005-01-01

    This paper has been removed by arXiv administrators because it plagiarizes gr-qc/0011027, "Viscous cosmologies in scalar-tensor theories for Kasner type metrics," by M. Cataldo, S. del Campo and P. Salgado.

  20. On the field theory of the extended-type electron

    In a recent paper, the classical theory of Barut and Zhanghi (BZ) for the electron spin [which interpreted the Zitterbewegung (zbw) motion as an internal motion along helical paths] and its ''quantum'' version have been investigated by using the language of Clifford algebras. In so doing, a new non-linear Dirac-like equation (NDE) was derived. We want to readdress the whole subject, and ''complete'' it, by adopting - for the sake of physical clarity - the ordinary tensorial language, within the frame of a first quantization formalism. In particular, we re-derive here the NDE for the electron field, show it to be associated with a new conserved probability current which allows us to work out a quantum probability interpretation of NDE. Actually, we propose this equation in substitution for the Dirac equation, which is obtained from the former by averaging over a zbw cycle. We then derive a new equation of motion for the 4-velocity field which will allow us to regard the electron as an extended object with a classically intelligible internal structure (thus overcoming some known, long-standing problems). We carefully study the solutions of the NDE; with special attention to those implying (at the classical limit) light-like helical motions, since they appear to be the most adequate solutions for the electron description from a kinematical and physical point of view, and to cope with the electromagnetic properties of the electron. (author). 18 refs

  1. Quantum Field Theory Applications of Heun Type Functions

    Birkandan, T

    2016-01-01

    After a brief introduction to Heun type functions we note that the actual solutions of the eigenvalue equation emerging in the calculation of the one loop contribution to QCD from the Belavin-Polyakov-Schwarz-Tyupkin instanton and the similar calculation for a Dirac particle coupled to a scalar $CP^1$ model in two dimensions can be given in terms of confluent Heun equation in their original forms. These equations were previously modified to be solved by more elementary functions. We also show that polynomial solutions with discrete eigenvalues are impossible to find in the unmodified equations.

  2. Theory of zeolite supralattices: Se in zeolite Linde type A

    We study theoretically properties of Se clusters in zeolites, and choose zeolite Linde type A (LTA) as a prototype system. The geometries of free-space Se clusters are first determined, and we report the energetics and electronic and vibrational properties of these clusters. The work on clusters includes an investigation of the energetics of C3-C1 defect formation in Se rings and chains. The electronic properties of two Se crystalline polymorphs, trigonal Se and -monoclinic Se, are also determined. Electronic and vibrational properties of the zeolite LTA are investigated. Next we investigate the electronic and optical properties of ring-like Se clusters inside the large -cages of LTA. We find that Se clusters inside cages of silaceous LTA have very little interaction with the zeolite, and that the HOMO-LUMO gaps (HOMO standing for highest occupied molecular orbital and LUMO for lowest unoccupied molecular orbital) are nearly those of the isolated cluster. The HOMO-LUMO gaps of Se6, Se8, and Se12 are found to be similar, which makes it difficult to identify them experimentally by absorption spectroscopy. We find that the zeolite/Se8 nanocomposite is lower in energy than the two separated systems. We also investigate two types of infinite chain encapsulated in LTA. Finally, we carry out finite-temperature molecular dynamics simulations for an encapsulated Se12 cluster, which shows cluster melting and formation of nanoscale Se droplets in theα-cages of LTA. (author)

  3. $\\mathcal{N}=2$ supersymmetric field theories on 3-manifolds with A-type boundaries

    Aprile, Francesco

    2016-01-01

    General half-BPS A-type boundary conditions are formulated for N=2 supersymmetric field theories on compact 3-manifolds with boundary. We observe that under suitable conditions manifolds of the real A-type admitting two complex supersymmetries (related by charge conjugation) possess, besides a contact structure, a natural integrable toric foliation. A boundary, or a general co-dimension-1 defect, can be inserted along any leaf of this preferred foliation to produce manifolds with boundary that have the topology of a solid torus. We show that supersymmetric field theories on such manifolds can be endowed with half-BPS A-type boundary conditions. We specify the natural curved space generalization of the A-type projection of bulk supersymmetries and analyze the resulting A-type boundary conditions in generic 3d non-linear sigma models and YM/CS-matter theories.

  4. Russell´s Early Type Theory and the Paradox of Propositions

    André Fuhrmann

    2001-12-01

    Full Text Available The paradox of propositions, presented in Appendix B of Russell's The Principles of Mathematics (1903, is usually taken as Russell's principal motive, at the time, for moving from a simple to a ramified theory of types. I argue that this view is mistaken. A closer study of Russell's correspondence with Frege reveals that Russell carne to adopt a very different resolution of the paradox, calling into question not the simplicity of his early type theory but the simplicity of his early theory of propositions.

  5. Vortex-type half-BPS solitons in Aharony-Bergman-Jafferis-Maldacena theory

    We study the Aharony-Bergman-Jafferis-Maldacena (ABJM) theory without and with mass deformation. It is shown that maximally supersymmetry preserving, D-term, and F-term mass deformations of single mass parameter are equivalent. We obtain vortex-type half-BPS equations and the corresponding energy bound. For the undeformed ABJM theory, the resulting half-BPS equation is the same as that in supersymmetric Yang-Mills theory and no finite energy regular BPS solution is found. For the mass-deformed ABJM theory, the half-BPS equations for U(2)xU(2) case reduce to the vortex equation in Maxwell-Higgs theory, which supports static regular multivortex solutions. In U(N)xU(N) case with N>2 the non-Abelian vortex equation of Yang-Mills-Higgs theory is obtained.

  6. D-branes and dual gauge theories in type 0 strings

    We consider the type 0 theories, obtained from the closed NSR string by a diagonal GSO projection which excludes space-time fermions, and study the D-branes in these theories. The low-energy dynamics of N coincident D-branes is governed by a U(N) gauge theory coupled to adjoint scalar fields. It is tempting to look for the type 0 string duals of such bosonic gauge theories in the background of the R-R charged p-brane classical solutions. This results in a picture analogous to the one recently proposed by Polyakov (hep-th/9809057). One of the serious problems that needs to be resolved is the closed string tachyon mode which couples to the D-branes and appears to cause an instability. We study the tachyon terms in the type 0 effective action and argue that the background R-R flux provides a positive shift of the (mass)2 of the tachyon. Thus, for sufficiently large flux, the tachyonic instability may be cured, removing the most basic obstacle to constructing the type 0 duals of non-supersymmetric gauge theories. We further find that the tachyon acquires an expectation value in the presence of the R-R flux. This effect is crucial for breaking the conformal invariance in the dual description of the 3 + 1-dimensional non-supersymmetric gauge theory

  7. Theory of chromatography of partially cyclic polymers: Tadpole-type and manacle-type macromolecules.

    Vakhrushev, Andrey V; Gorbunov, Alexei A

    2016-02-12

    A theory of chromatography is developed for partially cyclic polymers of tadpole- and manacle-shaped topological structures. We present exact equations for the distribution coefficient K at different adsorption interactions; simpler approximate formulae are also derived, relevant to the conditions of size-exclusion, adsorption, and critical chromatography. Theoretical chromatograms of heterogeneous partially cyclic polymers are simulated, and conditions for good separation by topology are predicted. According to the theory, an effective SEC-radius of tadpoles and manacles is mostly determined by the molar mass M, and by the linear-cyclic composition. In the interactive chromatography, the effect of molecular topology on the retention becomes significant. At the critical interaction point, partial dependences K(Mlin) and K(Mring) are qualitatively different: while being almost independent of Mlin, K increases with Mring. This behavior could be realized in critical chromatography-for separation of partially cyclic polymers by the number and molar mass of cyclic elements. PMID:26803439

  8. Relative quantification and detection of different types of infectious bursal disease virus in bursa of Fabricius and cloacal swabs using real time RT-PCR SYBR green technology

    Li, Yiping; Handberg, K.J.; Kabell, Susanne; Kusk, M.; Zhang, M.F.; Jorgensen, P.H.

    2007-01-01

    In present study, different types of infectious bursal disease virus (IBDV), virulent strain DK01, classic strain F52/70 and vaccine strain D78 were quantified and detected in infected bursa of Fabricius (BF) and cloacal swabs using quantitative real time RT-PCR with SYBR green dye. For selection...... of a suitable internal control gene, real time PCR parameters were evaluated for three candidate genes, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), 28S rRNA and beta-actin to IBDVs. Based on this P-actin was selected as an internal control for quantification of IBDVs in BF. All BF samples with...... primers. The method described here is robust and may sever as a useful tool with high capacity for diagnostics as well as in viral pathogenesis studies....

  9. On the usage of classical nucleation theory in quantification of the impact of bacterial INP on weather and climate

    Sahyoun, Maher; Wex, Heike; Gosewinkel, Ulrich; Šantl-Temkiv, Tina; Nielsen, Niels W.; Finster, Kai; Sørensen, Jens H.; Stratmann, Frank; Korsholm, Ulrik S.

    2016-08-01

    Bacterial ice-nucleating particles (INP) are present in the atmosphere and efficient in heterogeneous ice-nucleation at temperatures up to -2 °C in mixed-phase clouds. However, due to their low emission rates, their climatic impact was considered insignificant in previous modeling studies. In view of uncertainties about the actual atmospheric emission rates and concentrations of bacterial INP, it is important to re-investigate the threshold fraction of cloud droplets containing bacterial INP for a pronounced effect on ice-nucleation, by using a suitable parameterization that describes the ice-nucleation process by bacterial INP properly. Therefore, we compared two heterogeneous ice-nucleation rate parameterizations, denoted CH08 and HOO10 herein, both of which are based on classical-nucleation-theory and measurements, and use similar equations, but different parameters, to an empirical parameterization, denoted HAR13 herein, which considers implicitly the number of bacterial INP. All parameterizations were used to calculate the ice-nucleation probability offline. HAR13 and HOO10 were implemented and tested in a one-dimensional version of a weather-forecast-model in two meteorological cases. Ice-nucleation-probabilities based on HAR13 and CH08 were similar, in spite of their different derivation, and were higher than those based on HOO10. This study shows the importance of the method of parameterization and of the input variable, number of bacterial INP, for accurately assessing their role in meteorological and climatic processes.

  10. Uncertainty quantification in modeling earth surface processes: more applicable for some types of models than for others

    Murray, A. Brad; Gasparini, Nicole M.; Goldstein, Evan B.; van der Wegen, Mick

    2016-05-01

    In Earth-surface science, numerical models are used for a range of purposes, from making quantitatively accurate predictions for practical or scientific purposes ('simulation' models) to testing hypotheses about the essential causes of poorly understood phenomena ('exploratory' models). We argue in this contribution that whereas established methods for uncertainty quantification (UQ) are appropriate (and crucial) for simulation models, their application to exploratory models are less straightforward, and in some contexts not relevant. Because most models fall between the end members of simulation and exploratory models, examining the model contexts under which UQ is most and least appropriate is needed. Challenges to applying state-of-the-art UQ to Earth-surface science models center on quantifying 'model-form' uncertainty-the uncertainty in model predictions related to model imperfections. These challenges include: 1) the difficulty in deterministically comparing model predictions to observations when positive feedbacks and associated autogenic dynamics (a.k.a. 'free' morphodynamics) determine system behavior over the timescales of interest (a difficulty which could be mitigated in a UQ approach involving statistical comparisons); 2) the lack of available data sets at sufficiently large space and/or time scales; 3) the inability to disentangle uncertainties arising from model parameter values and model form in some cases; and 4) the inappropriateness of model 'validation' in the UQ sense for models toward the exploratory end member of the modeling spectrum.

  11. Digital Games for Type 1 and Type 2 Diabetes: Underpinning Theory With Three Illustrative Examples

    Gammon, Shauna; Dixon, Mavis C; MacRury, Sandra M; Fergusson, Michael J; Miranda Rodrigues, Francisco; Mourinho Baptista, Telmo; Yang, Stephen P

    2015-01-01

    Digital games are an important class of eHealth interventions in diabetes, made possible by the Internet and a good range of affordable mobile devices (eg, mobile phones and tablets) available to consumers these days. Gamifying disease management can help children, adolescents, and adults with diabetes to better cope with their lifelong condition. Gamification and social in-game components are used to motivate players/patients and positively change their behavior and lifestyle. In this paper, we start by presenting the main challenges facing people with diabetes—children/adolescents and adults—from a clinical perspective, followed by three short illustrative examples of mobile and desktop game apps and platforms designed by Ayogo Health, Inc. (Vancouver, BC, Canada) for type 1 diabetes (one example) and type 2 diabetes (two examples). The games target different age groups with different needs—children with type 1 diabetes versus adults with type 2 diabetes. The paper is not meant to be an exhaustive review of all digital game offerings available for people with type 1 and type 2 diabetes, but rather to serve as a taster of a few of the game genres on offer today for both types of diabetes, with a brief discussion of (1) some of the underpinning psychological mechanisms of gamified digital interventions and platforms as self-management adherence tools, and more, in diabetes, and (2) some of the hypothesized potential benefits that might be gained from their routine use by people with diabetes. More research evidence from full-scale evaluation studies is needed and expected in the near future that will quantify, qualify, and establish the evidence base concerning this gamification potential, such as what works in each age group/patient type, what does not, and under which settings and criteria. PMID:25791276

  12. Digital games for type 1 and type 2 diabetes: underpinning theory with three illustrative examples.

    Kamel Boulos, Maged N; Gammon, Shauna; Dixon, Mavis C; MacRury, Sandra M; Fergusson, Michael J; Miranda Rodrigues, Francisco; Mourinho Baptista, Telmo; Yang, Stephen P

    2015-01-01

    Digital games are an important class of eHealth interventions in diabetes, made possible by the Internet and a good range of affordable mobile devices (eg, mobile phones and tablets) available to consumers these days. Gamifying disease management can help children, adolescents, and adults with diabetes to better cope with their lifelong condition. Gamification and social in-game components are used to motivate players/patients and positively change their behavior and lifestyle. In this paper, we start by presenting the main challenges facing people with diabetes-children/adolescents and adults-from a clinical perspective, followed by three short illustrative examples of mobile and desktop game apps and platforms designed by Ayogo Health, Inc. (Vancouver, BC, Canada) for type 1 diabetes (one example) and type 2 diabetes (two examples). The games target different age groups with different needs-children with type 1 diabetes versus adults with type 2 diabetes. The paper is not meant to be an exhaustive review of all digital game offerings available for people with type 1 and type 2 diabetes, but rather to serve as a taster of a few of the game genres on offer today for both types of diabetes, with a brief discussion of (1) some of the underpinning psychological mechanisms of gamified digital interventions and platforms as self-management adherence tools, and more, in diabetes, and (2) some of the hypothesized potential benefits that might be gained from their routine use by people with diabetes. More research evidence from full-scale evaluation studies is needed and expected in the near future that will quantify, qualify, and establish the evidence base concerning this gamification potential, such as what works in each age group/patient type, what does not, and under which settings and criteria. PMID:25791276

  13. How to obtain a covariant Breit type equation from relativistic Constraint Theory

    Mourad, J.; Sazdjian, H.

    1994-01-01

    It is shown that, by an appropriate modification of the structure of the interaction potential, the Breit equation can be incorporated into a set of two compatible manifestly covariant wave equations, derived from the general rules of Constraint Theory. The complementary equation to the covariant Breit type equation determines the evolution law in the relative time variable. The interaction potential can be systematically calculated in perturbation theory from Feynman diagrams. The normalizat...

  14. Seiberg-Witten-type Maps for Currents and Energy-Momentum Tensors in Noncommutative Gauge Theories

    Banerjee, Rabin; Lee, Choonkyu; Yang, Hyun Seok

    2003-01-01

    We derive maps relating the currents and energy-momentum tensors in noncommutative (NC) gauge theories with their commutative equivalents. Some uses of these maps are discussed. Especially, in NC electrodynamics, we obtain a generalization of the Lorentz force law. Also, the same map for anomalous currents relates the Adler-Bell-Jackiw type NC covariant anomaly with the standard commutative-theory anomaly. For the particular case of two dimensions, we discuss the implications of these maps fo...

  15. Four types of coping with COPD-induced breathlessness in daily living: a grounded theory study

    Bastrup, Lene; Dahl, Ronald; Pedersen, Preben Ulrich;

    2013-01-01

    COPD predominantly cope with breathlessness during daily living. We chose a multimodal grounded theory design that holds the opportunity to combine qualitative and quantitative data to capture and explain the multidimensional coping behaviour among poeple with COPD. The participants' main concern in...... coping with breathlessness appeared to be an endless striving to economise on resources in an effort to preserve their integrity. In this integrity-preserving process, four predominant coping types emerged and were labelled: `Overrater´, `Challenger´, `Underrater´, and `Leveller´. Each coping type...... comprised distrinctive physiological, cognitive, affective and psychosocial features constituting coping-type-specific indicators. In theory, four predominant coping types with distinct physiological, cognitive, affective and psychosocial properties are observed among people with COPD. The four coping types...

  16. Nonperturbative type IIB model building in the F-theory framework

    This dissertation is concerned with the topic of non-perturbative string theory, which is generally considered to be the most promising approach to a consistent description of quantum gravity. The five known 10-dimensional perturbative string theories are all interconnected by numerous dualities, such that an underlying non-perturbative 11-dimensional theory, called M-theory, is postulated. Due to several technical obstacles, little is known about the fundamental objects in this theory. There exists an alternative non-perturbative description to type IIB string theory, namely F-theory. Here the SL(2;Z) self-duality of IIB theory is geometrized in the form of an elliptic fibration over the space-time. Moreover, higher-dimensional objects like 7-branes are included via singularities into the geometric picture. This formally elegant description, however, requires significant technical effort for the construction of suitable compactification geometries, as many different aspects necessarily have to be dealt with at the same time. On the other hand, the generation of essential GUT building blocks like certain Yukawa couplings or spinor representations is easier compared to perturbative string theory. The goal of this study is therefore to formulate a unified theory within the framework of F-theory, that satisfies basic phenomenological constraints. Within this thesis, at first E3-brane instantons in type IIB string theory - 4-dimensional objects that are entirely wrapped around the invisible dimensions of space-time - are matched with M5-branes in F-theory. Such objects are of great importance in the generation of critical Yukawa couplings or the stabilization of the free parameters of a theory. Certain properties of M5-branes then allow to derive a new criterion for E3-branes to contribute to the superpotential. In the aftermath of this analysis, several compactification geometries are constructed and checked for basic properties that are relevant for semi

  17. Nonperturbative type IIB model building in the F-theory framework

    Jurke, Benjamin Helmut Friedrich

    2011-02-28

    This dissertation is concerned with the topic of non-perturbative string theory, which is generally considered to be the most promising approach to a consistent description of quantum gravity. The five known 10-dimensional perturbative string theories are all interconnected by numerous dualities, such that an underlying non-perturbative 11-dimensional theory, called M-theory, is postulated. Due to several technical obstacles, little is known about the fundamental objects in this theory. There exists an alternative non-perturbative description to type IIB string theory, namely F-theory. Here the SL(2;Z) self-duality of IIB theory is geometrized in the form of an elliptic fibration over the space-time. Moreover, higher-dimensional objects like 7-branes are included via singularities into the geometric picture. This formally elegant description, however, requires significant technical effort for the construction of suitable compactification geometries, as many different aspects necessarily have to be dealt with at the same time. On the other hand, the generation of essential GUT building blocks like certain Yukawa couplings or spinor representations is easier compared to perturbative string theory. The goal of this study is therefore to formulate a unified theory within the framework of F-theory, that satisfies basic phenomenological constraints. Within this thesis, at first E3-brane instantons in type IIB string theory - 4-dimensional objects that are entirely wrapped around the invisible dimensions of space-time - are matched with M5-branes in F-theory. Such objects are of great importance in the generation of critical Yukawa couplings or the stabilization of the free parameters of a theory. Certain properties of M5-branes then allow to derive a new criterion for E3-branes to contribute to the superpotential. In the aftermath of this analysis, several compactification geometries are constructed and checked for basic properties that are relevant for semi

  18. Bianchi Type VI1 Viscous Fluid Cosmological Model in Wesson´s Theory of Gravitation

    Khadekar, G. S.; Avachar, G. R.

    2007-03-01

    Field equations of a scale invariant theory of gravitation proposed by Wesson [1, 2] are obtained in the presence of viscous fluid with the aid of Bianchi type VIh space-time with the time dependent gauge function (Dirac gauge). It is found that Bianchi type VIh (h = 1) space-time with viscous fluid is feasible in this theory, whereas Bianchi type VIh (h = -1, 0) space-times are not feasible in this theory, even in the presence of viscosity. For the feasible case, by assuming a relation connecting viscosity and metric coefficient, we have obtained a nonsingular-radiating model. We have discussed some physical and kinematical properties of the models.

  19. Quantification on source/receptor relationship of primary pollutants and secondary aerosols from ground sources. Part 1. Theory

    A new algorithm has been derived for trajectory models to determine the transfer coefficient of each source along or adjacent to a trajectory and to calculate the concentrations of SO2 NOx, sulfate, nitrate, fine particulate matter (PM) and coarse PM at a receptor. The transfer coefficient tf(sm-1) is defined to be the ratio between the contributed concentration δC(μgm-3) to the receptor from a ground source and the emission rate of the source q (μgm-2s-1) at a grid. i.e. tfidentical toδC/q. The model is developed by combining with a backward trajectory scheme and a circuit-type's parameterization. First, the transfer coefficients of grids along or adjacent a back-trajectory are calculated. Then, the contributed concentration of each emission grid is determined by multiplying its emission rate with the transfer coefficient of the grid. Finally, the concentration at the receptor is determined by the summation of all the contributed concentrations within the domain of simulation. (author)

  20. Impaired Theory of Mind and psychosocial functioning among pediatric patients with Type I versus Type II bipolar disorder.

    Schenkel, Lindsay S; Chamberlain, Todd F; Towne, Terra L

    2014-03-30

    Deficits in Theory of Mind (ToM) have been documented among pediatric patients with Bipolar Disorder (BD). However, fewer studies have directly examined differences between type I and type II patients and whether or not ToM deficits are related to psychosocial difficulties. Therefore, the aim of this study was to compare type I versus type II pediatric bipolar patients and matched Healthy Controls (HC) on ToM and interpersonal functioning tasks. All participants completed the Revised Mind in the Eyes Task (MET), the Cognitive and Emotional Perspective Taking Task (CEPTT), and the Index of Peer Relations (IPR). Type I BD patients reported greater peer difficulties on the IPR compared to HC, and also performed more poorly on the MET and the cognitive condition of the CEPTT, but did not differ significantly on the emotional condition. There were no significant group differences between type II BD patients and HC. More impaired ToM performance was associated with poorer interpersonal functioning. Type I BD patients show deficits in the ability to understand another's mental state, irrespective of emotional valence. Deficits in understanding others' mental states could be an important treatment target for type I pediatric patients with BD. PMID:24461271

  1. Conference on Geometric Analysis &Conference on Type Theory, Homotopy Theory and Univalent Foundations : Extended Abstracts Fall 2013

    Yang, Paul; Gambino, Nicola; Kock, Joachim

    2015-01-01

    The two parts of the present volume contain extended conference abstracts corresponding to selected talks given by participants at the "Conference on Geometric Analysis" (thirteen abstracts) and at the "Conference on Type Theory, Homotopy Theory and Univalent Foundations" (seven abstracts), both held at the Centre de Recerca Matemàtica (CRM) in Barcelona from July 1st to 5th, 2013, and from September 23th to 27th, 2013, respectively. Most of them are brief articles, containing preliminary presentations of new results not yet published in regular research journals. The articles are the result of a direct collaboration between active researchers in the area after working in a dynamic and productive atmosphere. The first part is about Geometric Analysis and Conformal Geometry; this modern field lies at the intersection of many branches of mathematics (Riemannian, Conformal, Complex or Algebraic Geometry, Calculus of Variations, PDE's, etc) and relates directly to the physical world, since many natural phenomena...

  2. Seiberg-Witten-type Maps for Currents and Energy-Momentum Tensors in Noncommutative Gauge Theories

    Banerjee, R; Yang, H S; Banerjee, Rabin; Lee, Choonkyu; Yang, Hyun Seok

    2003-01-01

    We derive maps relating the currents and energy-momentum tensors in noncommutative (NC) gauge theories with their commutative equivalents. Some uses of these maps are discussed. Especially, in NC electrodynamics, we obtain a generalization of the Lorentz force law. Also, the same map for anomalous currents relates the Adler-Bell-Jackiw type NC covariant anomaly with the standard commutative-theory anomaly. For the particular case of two dimensions, we discuss the implications of these maps for the Sugawara-type energy-momentum tensor.

  3. Bianchi Type-I, V and VIo models in modified generalized scalar–tensor theory

    T Singh; R Chaubey

    2007-08-01

    In modified generalized scalar–tensor (GST) theory, the cosmological term is a function of the scalar field and its derivatives $\\dot{}^{2}$. We obtain exact solutions of the field equations in Bianchi Type-I, V and VIo space–times. The evolution of the scale factor, the scalar field and the cosmological term has been discussed. The Bianchi Type-I model has been discussed in detail. Further, Bianchi Type-V and VIo models can be studied on the lines similar to Bianchi Type-I model.

  4. Preclinical evaluation and quantification of [18F]MK-9470 as a radioligand for PET imaging of the type 1 cannabinoid receptor in rat brain

    [18F]MK-9470 is an inverse agonist for the type 1 cannabinoid (CB1) receptor allowing its use in PET imaging. We characterized the kinetics of [18F]MK-9470 and evaluated its ability to quantify CB1 receptor availability in the rat brain. Dynamic small-animal PET scans with [18F]MK-9470 were performed in Wistar rats on a FOCUS-220 system for up to 10 h. Both plasma and perfused brain homogenates were analysed using HPLC to quantify radiometabolites. Displacement and blocking experiments were done using cold MK-9470 and another inverse agonist, SR141716A. The distribution volume (VT) of [18F]MK-9470 was used as a quantitative measure and compared to the use of brain uptake, expressed as SUV, a simplified method of quantification. The percentage of intact [18F]MK-9470 in arterial plasma samples was 80 ± 23 % at 10 min, 38 ± 30 % at 40 min and 13 ± 14 % at 210 min. A polar radiometabolite fraction was detected in plasma and brain tissue. The brain radiometabolite concentration was uniform across the whole brain. Displacement and pretreatment studies showed that 56 % of the tracer binding was specific and reversible. VT values obtained with a one-tissue compartment model plus constrained radiometabolite input had good identifiability (≤10 %). Ignoring the radiometabolite contribution using a one-tissue compartment model alone, i.e. without constrained radiometabolite input, overestimated the [18F]MK-9470 VT, but was correlated. A correlation between [18F]MK-9470 VT and SUV in the brain was also found (R 2 = 0.26-0.33; p ≤ 0.03). While the presence of a brain-penetrating radiometabolite fraction complicates the quantification of [18F]MK-9470 in the rat brain, its tracer kinetics can be modelled using a one-tissue compartment model with and without constrained radiometabolite input. (orig.)

  5. LRS Bianchi Type-I Dark Energy Cosmological Models in General Scalar Tensor Theory of Gravitation

    D. Neelima; V. U. M. Rao

    2013-01-01

    Locally rotationally symmetric (LRS) Bianchi type-I dark energy cosmological model with variable equation of state (EoS) parameter in (Nordtvedt 1970) general scalar tensor theory of gravitation with the help of a special case proposed by (Schwinger 1970) is obtained. It is observed that these anisotropic and isotropic dark energy cosmological models always represent an accelerated universe and are consistent with the recent observations of type-Ia supernovae. Some important features of the m...

  6. The Classification of Gun’s Type Using Image Recognition Theory

    M.L.Kulthon Kasemsan

    2014-01-01

    The research aims to develop the Gun’s Type and Models Classification (GTMC) system using image recognition theory. It is expected that this study can serve as a guide for law enforcement agencies or at least serve as the catalyst for a similar type of research. Master image storage and image recognition are the two main processes. The procedures involved original images, scaling, gray scale, canny edge detector, SUSAN corner detector, block matching template, and finally gun type’s recogniti...

  7. Quantification and implications of two types of soluble organic matter from brackish to saline lake source rocks

    SONG Yitao; LIAO Yongsheng; ZHANG Shouchun

    2005-01-01

    Two types of soluble organic matter, the free and adsorbed, were obtained and quantified from the brackish to saline lake source rocks. The adsorbed type was extracted with chloroform, solvent mixtures of methanol: acetone:chloroform (MAC) and CS2:N-methyl-2-pyrroli- dinone (CS2/NMP). The total amounts of the two types of soluble organic matter from some immature source rocks are >830 mg/g TOC, more than 63% of the total organic matter in these samples. This result indicates that the majority of the organic matter in the immature source rocks in the brackish to saline lake basin is soluble, and is significant for study of petroleum formation and helpful for petroleum exploration in the brackish to saline lake basin.

  8. Quantification of the types of water in Eudragit RLPO polymer and the kinetics of water loss using FTIR

    Pirayavaraporn, Chompak; Rades, Thomas; Gordon, Keith C;

    2013-01-01

    . Using a curve fitting procedure, the water region (3100-3,700 cm(-1)) of the spectra was analyzed, and used to identify water present in differing environments in the polymer and to determine the water loss kinetics upon purging the sample with dry compressed air. It was found that four environments can......Coalescence of polymer particles in polymer matrix tablets influences drug release. The literature has emphasized that coalescence occurs above the glass transition temperature (Tg) of the polymer and that water may plasticize (lower Tg) the polymer. However, we have shown previously that...... nonplasticizing water also influences coalescence of Eudragit RLPO; so there is a need to quantify the different types of water in Eudragit RLPO. The purpose of this study was to distinguish the types of water present in Eudragit RLPO polymer and to investigate the water loss kinetics for these different types of...

  9. Isotropization of Bianchi type models and a new FRW solution in Brans-Dicke theory

    Cervantes-Cota, J L; Cervantes-Cota, Jorge L.; Nahmad, Marcos

    2001-01-01

    Using scaled variables we are able to integrate an equation valid for isotropic and anisotropic Bianchi type I, V, IX models in Brans-Dicke (BD) theory. We analyze known and new solutions for these models in relation with the possibility that anisotropic models asymptotically isotropize, and/or possess inflationary properties. In particular, a new solution of curve ($k\

  10. GENERAL RELIABILITY THEORY STUDY ON SEMI-FLEXIBLE OUTPUT TYPE AND REPAIRABLE PRODUCTION SYSTEM

    马云东; 高宏伟

    1996-01-01

    This paper puts forward the conceptions of semi-flexible units and semi-flexible system, and builds up the theory of semi-flexible output type and repairable production system general reliability analysis and general reliability design, which discusses the reliability problems of semi-flexible units and semi-flexible system from three aspects of time, task and capacity.

  11. Localized energy associated with Bianchi-Type VI universe in $f(R)$ theory of gravity

    Korunur, M

    2016-01-01

    In the present work, focusing on one of the most popular problems in modern gravitation theories, we consider generalized Lanndau-Liftshitz energy-momentum relation to calculate energy distribution of the Bianchi-Type VI spacetime in $f(R)$ gravity. Additionally, the results are specified by using some well-known $f(R)$-gravity models.

  12. Quantification of zinc atoms in a surface alloy on copper in an industrial-type methanol synthesis catalyst

    Kuld, Sebastian; Moses, Poul Georg; Sehested, Jens;

    2014-01-01

    Methanol has recently attracted renewed interest because of its potential importance as a solar fuel. Methanol is also an important bulk chemical that is most efficiently formed over the industrial Cu/ZnO/Al2O3 catalyst. The identity of the active site and, in particular, the role of ZnO as a...... promoter for this type of catalyst is still under intense debate. Structural changes that are strongly dependent on the pretreatment method have now been observed for an industrial-type methanol synthesis catalyst. A combination of chemisorption, reaction, and spectroscopic techniques provides a consistent...... picture of surface alloying between copper and zinc. This analysis enables a reinterpretation of the methods that have been used for the determination of the Cu surface area and provides an opportunity to independently quantify the specific Cu and Zn areas. This method may also be applied to other systems...

  13. Quantification of zinc atoms in a surface alloy on copper in an industrial-type methanol synthesis catalyst

    Kuld, Sebastian; Moses, Poul Georg; Sehested, Jens;

    2014-01-01

    Methanol has recently attracted renewed interest because of its potential importance as a solar fuel.1 Methanol is also an important bulk chemical that is most efficiently formed over the industrial Cu/ZnO/Al2O3 catalyst. The identity of the active site and, in particular, the role of ZnO as a...... promoter for this type of catalyst is still under intense debate.2 Structural changes that are strongly dependent on the pretreatment method have now been observed for an industrial-type methanol synthesis catalyst. A combination of chemisorption, reaction, and spectroscopic techniques provides a...... consistent picture of surface alloying between copper and zinc. This analysis enables a reinterpretation of the methods that have been used for the determination of the Cu surface area and provides an opportunity to independently quantify the specific Cu and Zn areas. This method may also be applied to other...

  14. Thermodynamic limit of the Nekrasov-type formula for E-string theory

    We give a proof of the Nekrasov-type formula proposed by one of the authors for the Seiberg-Witten prepotential for the E-string theory on ℝ4×T2. We take the thermodynamic limit of the Nekrasov-type formula following the example of Nekrasov-Okounkov and reproduce the Seiberg-Witten description of the prepotential. The Seiberg-Witten curve obtained directly from the Nekrasov-type formula is of genus greater than one. We find that this curve is transformed into the known elliptic curve by a simple map. We consider the cases in which the low energy theory has E8, E7⊕A1 or E6⊕A2 as a global symmetry

  15. E$_{6(6)}$ Exceptional Field Theory: Review and Embedding of Type IIB

    Baguet, Arnaud; Samtleben, Henning

    2015-01-01

    We review E$_{6(6)}$ exceptional field theory with a particular emphasis on the embedding of type IIB supergravity, which is obtained by picking the GL$(5)\\times {\\rm SL}(2)$ invariant solution of the section constraint. We work out the precise decomposition of the E$_{6(6)}$ covariant fields on the one hand and the Kaluza-Klein-like decomposition of type IIB supergravity on the other. Matching the symmetries, this allows us to establish the precise dictionary between both sets of fields. Finally, we establish on-shell equivalence. In particular, we show how the self-duality constraint for the four-form potential in type IIB is reconstructed from the duality relations in the off-shell formulation of the E$_{6(6)}$ exceptional field theory.

  16. Experimental quantification of dynamic forces and shaft motion in two different types of backup bearings under several contact conditions

    Lahriri, Said; Santos, Ilmar

    2013-01-01

    This paper treats the experimental study on a shaft impacting its stator for different cases. The paper focuses mainly on the measured contact forces and the shaft motion in two different types of backup bearings. As such, the measured contact forces are thoroughly studied. These measured contact...... forces enable the hysteresis loops to be computed and analyzed. Consequently, the contact forces are plotted against the local deformation in order to assess the contact force loss during the impacts. The shaft motion during contact with the backup bearing is verified with a two-sided spectrum analyses...

  17. Precision automation of cell type classification and sub-cellular fluorescence quantification from laser scanning confocal images

    Hardy Craig Hall

    2016-02-01

    Full Text Available While novel whole-plant phenotyping technologies have been successfully implemented into functional genomics and breeding programs, the potential of automated phenotyping with cellular resolution is largely unexploited. Laser scanning confocal microscopy has the potential to close this gap by providing spatially highly resolved images containing anatomic as well as chemical information on a subcellular basis. However, in the absence of automated methods, the assessment of the spatial patterns and abundance of fluorescent markers with subcellular resolution is still largely qualitative and time-consuming. Recent advances in image acquisition and analysis, coupled with improvements in microprocessor performance, have brought such automated methods within reach, so that information from thousands of cells per image for hundreds of images may be derived in an experimentally convenient time-frame. Here, we present a MATLAB-based analytical pipeline to 1 segment radial plant organs into individual cells, 2 classify cells into cell type categories based upon random forest classification, 3 divide each cell into sub-regions, and 4 quantify fluorescence intensity to a subcellular degree of precision for a separate fluorescence channel. In this research advance, we demonstrate the precision of this analytical process for the relatively complex tissues of Arabidopsis hypocotyls at various stages of development. High speed and robustness make our approach suitable for phenotyping of large collections of stem-like material and other tissue types.

  18. The structure of the R^8 term in type IIB string theory

    Basu, Anirban

    2013-01-01

    Based on the structure of the on-shell linearized superspace of type IIB supergravity, we argue that there is a non--BPS 16 derivative interaction in the effective action of type IIB string theory of the form (t_8 t_8 R^4)^2, which we call the R^8 interaction. It lies in the same supermultiplet as the G^8 R^4 interaction. Using the KLT relation, we analyse the structure of the tree level eight graviton scattering amplitude in the type IIB theory, which leads to the R^8 interaction at the linearized level. This involves an analysis of color ordered multi-gluon disc amplitudes in the type I theory, which shows an intricate pole structure and transcendentality consistent with various other interactions. Considerations of S-duality show that the R^8 interaction receives non-analytic contributions in the string coupling at one and two loops. Apart from receiving perturbative contributions, we show that the R^8 interaction receives a non-vanishing contribution in the one D-instanton-anti-instanton background at lea...

  19. The structure of the R8 term in type IIB string theory

    Based on the structure of the on-shell linearized superspace of type IIB supergravity, we argue that there is a non-BPS 16 derivative interaction in the effective action of type IIB string theory of the form (t8t8R4)2, which we call the R8 interaction. It lies in the same supermultiplet as the G8R4 interaction. Using the Kawai–Lewellen–Tye relation, we analyze the structure of the tree level eight-graviton scattering amplitude in the type IIB theory, which leads to the R8 interaction at the linearized level. This involves an analysis of color-ordered multi-gluon disc amplitudes in the type I theory, which shows an intricate pole structure and transcendentality consistent with various other interactions. Considerations of S-duality show that the R8 interaction receives non-analytic contributions in the string coupling at one and two loops. Apart from receiving perturbative contributions, we show that the R8 interaction receives a non-vanishing contribution in the one D-instanton-anti-instanton background at leading order in the weak coupling expansion. (paper)

  20. Heartbeat-related displacement of the thoracic aorta in patients with chronic aortic dissection type B: Quantification by dynamic CTA

    Weber, Tim F. [University of Heidelberg, Department of Diagnostic and Interventional Radiology, Im Neuenheimer Feld 110, 69120 Heidelberg (Germany)], E-mail: tim.weber@med.uni-heidelberg.de; Ganten, Maria-Katharina [German Cancer Research Center, Department of Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg (Germany)], E-mail: m.ganten@dkfz.de; Boeckler, Dittmar [University of Heidelberg, Department of Vascular and Endovascular Surgery, Im Neuenheimer Feld 110, 69120 Heidelberg (Germany)], E-mail: dittmar.boeckler@med.uni-heidelberg.de; Geisbuesch, Philipp [University of Heidelberg, Department of Vascular and Endovascular Surgery, Im Neuenheimer Feld 110, 69120 Heidelberg (Germany)], E-mail: philipp.geisbuesch@med.uni-heidelberg.de; Kauczor, Hans-Ulrich [University of Heidelberg, Department of Diagnostic and Interventional Radiology, Im Neuenheimer Feld 110, 69120 Heidelberg (Germany)], E-mail: hu.kauczor@med.uni-heidelberg.de; Tengg-Kobligk, Hendrik von [German Cancer Research Center, Department of Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg (Germany)], E-mail: h.vontengg@dkfz.de

    2009-12-15

    Purpose: The purpose of this study was to characterize the heartbeat-related displacement of the thoracic aorta in patients with chronic aortic dissection type B (CADB). Materials and methods: Electrocardiogram-gated computed tomography angiography was performed during inspiratory breath-hold in 11 patients with CADB: Collimation 16 mm x 1 mm, pitch 0.2, slice thickness 1 mm, reconstruction increment 0.8 mm. Multiplanar reformations were taken for 20 equidistant time instances through both ascending (AAo) and descending aorta (true lumen, DAoT; false lumen, DAoF) and the vertex of the aortic arch (VA). In-plane vessel displacement was determined by region of interest analysis. Results: Mean displacement was 5.2 {+-} 1.7 mm (AAo), 1.6 {+-} 1.0 mm (VA), 0.9 {+-} 0.4 mm (DAoT), and 1.1 {+-} 0.4 mm (DAoF). This indicated a significant reduction of displacement from AAo to VA and DAoT (p < 0.05). The direction of displacement was anterior for AAo and cranial for VA. Conclusion: In CADB, the thoracic aorta undergoes a heartbeat-related displacement that exhibits an unbalanced distribution of magnitude and direction along the thoracic vessel course. Since consecutive traction forces on the aortic wall have to be assumed, these observations may have implications on pathogenesis of and treatment strategies for CADB.

  1. WKB - type approximations in the theory of vacuum particle creation in strong fields

    Smolyansky, S A; Panferov, A D; Prozorkevich, A V; Blaschke, D; Juchnowski, L

    2014-01-01

    Within the theory of vacuum creation of an $e^{+}e^{-}$ - plasma in the strong electric fields acting in the focal spot of counter-propagating laser beams we compare predictions on the basis of different WKB-type approximations with results obtained in the framework of a strict kinetic approach. Such a comparison demonstrates a considerable divergence results. We analyse some reasoning for this observation and conclude that WKB-type approximations have an insufficient foundation for QED in strong nonstationary fields. The results obtained in this work on the basis of the kinetic approach are most optimistic for the observation of an $e^{+}e^{-}$ - plasma in the range of optical and x-ray laser facilities. We discuss also the influence of unphysical features of non-adiabatic field models on the reliability of predictions of the kinetic theory.

  2. Asymptotic freedom and infrared behavior in the type 0 string approach to gauge theory

    In a recent paper we considered the type 0 string theories, obtained from the ten-dimensional closed NSR string by a GSO projection which excludes space-time fermions, and studied the low-energy dynamics of N coincident D-branes. This led us to conjecture that the four-dimensional SU(N) gauge theory coupled to six adjoint massless scalars is dual to a background of type 0 theory carrying N units of R-R 5-form flux and involving a tachyon condensate. The tachyon background leads to a 'soft breaking' of conformal invariance, and we derived the corresponding renormalization group equation. Minahan has subsequently found its asymptotic solution for weak coupling and showed that the coupling exhibits logarithmic flow, as expected from the asymptotic freedom of the dual gauge theory. We study this solution in more detail and identify the effect of the 2-loop beta function. We also demonstrate the existence of a fixed point at infinite coupling. Just like the fixed point at zero coupling, it is characterized by the AdS5 x S5 Einstein frame metric. We argue that there is a RG trajectory extending all the way from the zero coupling fixed point in the UV to the infinite coupling fixed point in the IR

  3. Supersymmetry and the Systematics of T-duality Rotations in Type-II Superstring Theories

    Hassan, S F

    2001-01-01

    We describe a systematic method of studying the action of the T-duality group O(d,d) on space-time fermions and R-R field strengths and potentials in type-II string theories, based on space-time supersymmetry. The formalism is then used to show that the couplings of non-Abelian D-brane charges to R-R potentials can be described by an appropriate Clifford multiplication.

  4. Cultivating New-type Farmers Based on the Theory of Human Resources Development

    Zhang, Li

    2010-01-01

    Under the direction of theory of human resources development, this thesis analyzes the impact of rural human resources development on cultivating new-type farmers. Firstly, it increases the input of rural basic education; secondly, it reinforces the vocational education and technology training; thirdly, it promotes the rural medical and public health services; fourthly, it quickens the rural labor transfer. The status quo of China’s rural human resources has been analyzed as follows: in ter...

  5. The criticality problem in reflected slab type reactor in the two-group transport theory

    The criticality problem in reflected slab type reactor is solved for the first time in the two group neutron transport theory, by singular eingenfunctions expansion, the singular integrals obtained through continuity conditions of angular distributions at the interface are regularized by a recently proposed method. The result is a coupled system of regular integral equations for the expansion coefficients, this system is solved by an ordinary interactive method. Numerical results that can be utilized as a comparative standard for aproximation methods, are presented

  6. World Sheet Superstring and Superstring Field Theory: a new solution using Ultradistributions of Exponential Type

    Bollini, C G; Rocca, M C

    2008-01-01

    In this paper we show that Ultradistributions of Exponential Type (UET) are appropriate for the description in a consistent way world sheet superstring and superstring field theories. A new Lagrangian for the closed world sheet superstring is obtained. We also show that the superstring field is a linear superposition of UET of compact support (CUET), and give the notion of anti-superstring. We evaluate the propagator for the string field, and calculate the convolution of two of them.

  7. Bianchi type VI1 cosmological model with wet dark fluid in scale invariant theory of gravitation

    Mishra, B

    2014-01-01

    In this paper, we have investigated Bianchi type VIh, II and III cosmological model with wet dark fluid in scale invariant theory of gravity, where the matter field is in the form of perfect fluid and with a time dependent gauge function (Dirac gauge). A non-singular model for the universe filled with disorder radiation is constructed and some physical behaviors of the model are studied for the feasible VIh (h = 1) space-time.

  8. Flux vacua in Dirac-Born-Infeld type Einstein-Maxwell theory

    Maki, Takuya; Kobayashi, Koichiro; Shiraishi, Kiyoshi

    2011-01-01

    We study compactification of extra dimensions in a theory of Dirac-Born-Infeld (DBI) type gravity. We investigate the solution for Minkowski spacetime with an $S^{2}$ extra space. The solution is derived by the effective potential method in the presence of the magnetic flux on the extra sphere. We find that, in a certain model, the radius of the extra space has a minimum value independent of the higher-dimensional Newton constant in weak-field limit.

  9. LRS Bianchi Type-I Inflationary String Cosmological Model in Brans-Dicke Theory of Gravitation

    R. Venkateswarlu

    2014-01-01

    Full Text Available We investigate locally rotational symmetric (LRS Bianchi type I space time coupled with scalar field. String cosmological models generated by a cloud of strings with particles attached to them are studied in the Brans-Dicke theory. We assume that the expansion scalar is proportional to the shear scalar and also power law ansatz for scalar field. The physical behavior of the resulting model is discussed through different parameters.

  10. Phenomenological theory of 1-3 type multiferroic composite thin film: thickness effect

    The effect of thickness on the para-ferro-phase transition temperatures, the spontaneous polarization and magnetization and hysteresis loops of 1-3 type multiferroic composite thin films was studied in the framework of Landau phenomenological theory. We took into account the electrostrictive and magnetostrictive effects, misfit strains induced from the interfaces of ferroelectric/ferromagnetic portions and film/substrate. Butterfly loops under external fields were also simulated.

  11. Phenomenological theory of 1-3 type multiferroic composite thin film: thickness effect

    Lu Xiaoyan; Wang Biao; Zheng Yue [School of Astronautics, Harbin Institute of Technology, Harbin 150001 (China); Ryba, Earle [Department of Materials Science and Engineering, Pennsylvania State University, University Park, PA, 16802 (United States)], E-mail: wangbiao@mail.sysu.edu.cn

    2009-01-07

    The effect of thickness on the para-ferro-phase transition temperatures, the spontaneous polarization and magnetization and hysteresis loops of 1-3 type multiferroic composite thin films was studied in the framework of Landau phenomenological theory. We took into account the electrostrictive and magnetostrictive effects, misfit strains induced from the interfaces of ferroelectric/ferromagnetic portions and film/substrate. Butterfly loops under external fields were also simulated.

  12. G\\"odel and G\\"odel-type universes in Brans-Dicke theory

    Agudelo, J A; Petrov, A Yu; Porfírio, P J; Santos, A F

    2016-01-01

    In this paper, conditions for existence of G\\"{o}del and G\\"{o}del-type solutions in Brans-Dicke (BD) scalar-tensor theory and their main features are studied. The special attention is paid to consistency of equations of motion, causality, existence of CTCs (closed time-like curves) and to the role which cosmological constant and Mach principle play to achieve the consistency of this model.

  13. Specimens: "most of" generic NPs in a contextually flexible type theory

    Retoré, Christian

    2011-01-01

    This paper proposes to compute the meanings associated to sentences with generic NPs corresponding to the most of generalized quantifier. We call these generics specimens and they resemble stereotypes or prototypes in lexical semantics. The meanings are viewed as logical formulae that can be thereafter interpreted in your favorite models. We rather depart from the dominant Fregean single untyped universe and go for type theory with hints from Hilbert epsilon calculus and from medieval philosophy. Our type theoretic analysis bears some resemblance with on going work in lexical semantics. Our model also applies to classical examples involving a class (or a generic element of this class) which is provided by the context. An outcome of this study is that, in the minimalism-contextualism debate, if one adopts a type theoretical view, terms encode the purely semantic meaning component while their typing is pragmatically determined.

  14. A Review of Different Types of Subsidies and How They Work in Theory

    Gerson, Kampungu k.; Han, Feng

    2013-01-01

    This paper gives a brief review on types of subsidies and how they work in theory. The paper identified three types of subsidies: subsidies that increase revenue, subsidies that lower the cost of production, and subsidies that are not linked to production or input. With the use of graphic examples to describe the partial effects of subsidies on supply and demand, the following findings were obtained: one, for producers to sell more, they will need to produce more, and in order to produce more...

  15. Spatially Homogeneous Bianchi Type V Cosmological Model in the Scale-Covariant Theory of Gravitation

    Shri Ram; M.K.Verma; Mohd.Zeyauddin

    2009-01-01

    We discuss spatially homogeneous and anisotropic Bianchi type-V spacetime filled with a perfect fluid in the framework of the scaie-covariant theory of gravitation proposed by Canuto et al.By applying the law of variation for Hubble's parameter,exact solutions of the field equations are obtained,which correspond to the model of the universe having a big-bang type singularity at the initial time t=0.The cosmological model,evolving from the initial singularity,expands with power-law expansion and gives essentially an empty space for a large time.The physical and dynamical properties of the model are also discussed.

  16. Fluxes, moduli fixing and MSSM-like vacua in Type IIA String Theory

    Camara, P G

    2006-01-01

    We review some of the features of Type IIA compactifications in the presence of fluxes. In particular, the case of $T^6/(\\Omega (-1)^{F_L} \\sigma)$ orientifolds with RR, NS and metric fluxes is considered. This has revealed to possess remarkable properties such as vacua with all the closed string moduli stabilized, null or negative contributions to the RR tadpoles or supersymmetry on the branes enforced by the closed string background. In this way, Type IIA compactifications with non trivial fluxes seem to constitute a new window into the building of semi-realistic models in String Theory.

  17. Quantification of the physiochemical constraints on the export of spider silk proteins by Salmonella type III secretion

    Voigt Christopher A

    2010-10-01

    Full Text Available Abstract Background The type III secretion system (T3SS is a molecular machine in gram negative bacteria that exports proteins through both membranes to the extracellular environment. It has been previously demonstrated that the T3SS encoded in Salmonella Pathogenicity Island 1 (SPI-1 can be harnessed to export recombinant proteins. Here, we demonstrate the secretion of a variety of unfolded spider silk proteins and use these data to quantify the constraints of this system with respect to the export of recombinant protein. Results To test how the timing and level of protein expression affects secretion, we designed a hybrid promoter that combines an IPTG-inducible system with a natural genetic circuit that controls effector expression in Salmonella (psicA. LacO operators are placed in various locations in the psicA promoter and the optimal induction occurs when a single operator is placed at the +5nt (234-fold and a lower basal level of expression is achieved when a second operator is placed at -63nt to take advantage of DNA looping. Using this tool, we find that the secretion efficiency (protein secreted divided by total expressed is constant as a function of total expressed. We also demonstrate that the secretion flux peaks at 8 hours. We then use whole gene DNA synthesis to construct codon optimized spider silk genes for full-length (3129 amino acids Latrodectus hesperus dragline silk, Bombyx mori cocoon silk, and Nephila clavipes flagelliform silk and PCR is used to create eight truncations of these genes. These proteins are all unfolded polypeptides and they encompass a variety of length, charge, and amino acid compositions. We find those proteins fewer than 550 amino acids reliably secrete and the probability declines significantly after ~700 amino acids. There also is a charge optimum at -2.4, and secretion efficiency declines for very positively or negatively charged proteins. There is no significant correlation with hydrophobicity

  18. Resonant modal group theory of membrane-type acoustical metamaterials for low-frequency sound attenuation

    Ma, Fuyin; Wu, Jiu Hui; Huang, Meng

    2015-09-01

    In order to overcome the influence of the structural resonance on the continuous structures and obtain a lightweight thin-layer structure which can effectively isolate the low-frequency noises, an elastic membrane structure was proposed. In the low-frequency range below 500 Hz, the sound transmission loss (STL) of this membrane type structure is greatly higher than that of the current sound insulation material EVA (ethylene-vinyl acetate copo) of vehicle, so it is possible to replace the EVA by the membrane-type metamaterial structure in practice engineering. Based on the band structure, modal shapes, as well as the sound transmission simulation, the sound insulation mechanism of the designed membrane-type acoustic metamaterials was analyzed from a new perspective, which had been validated experimentally. It is suggested that in the frequency range above 200 Hz for this membrane-mass type structure, the sound insulation effect was principally not due to the low-level locally resonant mode of the mass block, but the continuous vertical resonant modes of the localized membrane. So based on such a physical property, a resonant modal group theory is initially proposed in this paper. In addition, the sound insulation mechanism of the membrane-type structure and thin plate structure were combined by the membrane/plate resonant theory.

  19. Type synthesis for 4-DOF parallel press mechanism using GF set theory

    He, Jun; Gao, Feng; Meng, Xiangdun; Guo, Weizhong

    2015-07-01

    Parallel mechanisms is used in the large capacity servo press to avoid the over-constraint of the traditional redundant actuation. Currently, the researches mainly focus on the performance analysis for some specific parallel press mechanisms. However, the type synthesis and evaluation of parallel press mechanisms is seldom studied, especially for the four degrees of freedom(DOF) press mechanisms. The type synthesis of 4-DOF parallel press mechanisms is carried out based on the generalized function(GF) set theory. Five design criteria of 4-DOF parallel press mechanisms are firstly proposed. The general procedure of type synthesis of parallel press mechanisms is obtained, which includes number synthesis, symmetrical synthesis of constraint GF sets, decomposition of motion GF sets and design of limbs. Nine combinations of constraint GF sets of 4-DOF parallel press mechanisms, ten combinations of GF sets of active limbs, and eleven combinations of GF sets of passive limbs are synthesized. Thirty-eight kinds of press mechanisms are presented and then different structures of kinematic limbs are designed. Finally, the geometrical constraint complexity( GCC), kinematic pair complexity( KPC), and type complexity( TC) are proposed to evaluate the press types and the optimal press type is achieved. The general methodologies of type synthesis and evaluation for parallel press mechanism are suggested.

  20. Type and structure of time-like singularities in general relativity theory

    A method is proposed which permits one to deterMine whether a time-like singularity refers to a point, linear or some other type of gravitational field singularity. It is shown that in the general theory of relativity an altogether different type of source may be possible which does not have any analogs in finite curvature space. An analysis is made of a number of solutions containing time-like singularities whose type varies depending on the sign of the functions involved in the solutions. The form of the solution near simple linear sources and of generalized anisotropic solutions is determined more accurately. The space-time described by the γ-metric is investigated completely and the form of the metric near the ends and at singular points of linear Weyl singularities is found

  1. A Density Functional Theory Study of Doped Tin Monoxide as a Transparent p-type Semiconductor

    Bianchi Granato, Danilo

    2012-05-01

    In the pursuit of enhancing the electronic properties of transparent p-type semiconductors, this work uses density functional theory to study the effects of doping tin monoxide with nitrogen, antimony, yttrium and lanthanum. An overview of the theoretical concepts and a detailed description of the methods employed are given, including a discussion about the correction scheme for charged defects proposed by Freysoldt and others [Freysoldt 2009]. Analysis of the formation energies of the defects points out that nitrogen substitutes an oxygen atom and does not provide charge carriers. On the other hand, antimony, yttrium, and lanthanum substitute a tin atom and donate n-type carriers. Study of the band structure and density of states indicates that yttrium and lanthanum improves the hole mobility. Present results are in good agreement with available experimental works and help to improve the understanding on how to engineer transparent p-type materials with higher hole mobilities.

  2. Canonical BF-type topological field theory and fractional statistics of strings

    We consider BF-type topological field theory coupled to non-dynamical particle and string sources on spacetime manifolds of the form R1xM 3, where M 3 is a 3-manifold without boundary. Canonical quantization of the theory is carried out in the hamiltonian formalism and explicit solutions of the Schroedinger equation are obtained. We show that the Hilbert space is finite dimensional and the physical states carry a one-dimensional projective representation of the local gauge symmetries. When M 3 is homologically non-trivial the wavefunctions in addition carry a multi-dimensional projective representation, in terms of the linking matrix of the homology cycles of M 3, of the discrete group of large gauge transformations. The wavefunctions also carry a one-dimensional representation of the non-trivial linking of the particle trajectories and string surfaces in M 3. This topological field theory therefore provides a phenomenological generalization of anyons to (3+1) dimensions where the holonomies representing fractional statistics arise from the adiabatic transport of particles around strings. We also discuss a duality between large gauge transformations and these linking operations around the homology cycles of M 3, and show that this canonical quantum field theory provides novel quantum representations of the cohomology of M 3 and its associated motion group. ((orig.))

  3. Axion decay constants at special points in type II string theory

    Honda, Masaki; Otsuka, Hajime

    2016-01-01

    We propose the mechanism to disentangle the decay constant of closed string axion from the string scale in the framework of type II string theory on Calabi-Yau manifold. We find that the quantum and geometrical corrections in the prepotential that arise at some special points in the moduli space widen the window of axion decay constant. In particular, around the small complex structure points, the axion decay constant becomes significantly lower than the string scale. We also discuss the moduli stabilization leading to the phenomenologically attractive low-scale axion decay constant.

  4. Reissner-Nordstr(o)m-de-Sitter-type Solution by a Gauge Theory of Gravity

    V. Enache; Camelia Popa; V. P(a)un; M. Agop

    2008-01-01

    We use the theory based on a gravitational gauge group (Wu's model) to obtain a spherical symmetric solution of the field equations for the gravitational potential on a Minkowski spacetime. The gauge group, the gauge covariant derivative, the strength tensor of the gauge field, the gauge invariant Lagrangean with the cosmological constant, the field equations of the gauge potentials with a gravitational energy-momentum tensor as well as with a tensor of the field of a point like source are determined. Finally, a Reissner-Nordstr(o)m-de Sitter-type metric on the gauge group space is obtained.

  5. T-dualization of type IIB superstring theory in double space

    Nikolić, Bojan

    2015-01-01

    In this article we offer the new interpretation of T-dualization procedure of type IIB superstring theory in double space framework. We use the ghost free action of type IIB superstring in pure spinor formulation in approximation of constant background fields up to the quadratic terms. T-dualization along any subset of the initial coordinates, $x^a$, is equivalent to the permutation of this subset with subset of the corresponding T-dual coordinates, $y_a$, in double space coordinate $Z^M=(x^\\mu,y_\\mu)$. Demanding that the T-dual transformation law after exchange $x^a\\leftrightarrow y_a$ has the same form as initial one, we obtain the T-dual NS-NS and NS-R background fields. The T-dual R-R field strength is determined up to one arbitrary constant under some assumptions.

  6. A Global View on The Search for de-Sitter Vacua in (type IIA) String Theory

    Chen, Xingang; Sumitomo, Yoske; Tye, S -H Henry

    2011-01-01

    The search for classically stable Type IIA de-Sitter vacua typically starts with an ansatz that gives Anti-de-Sitter supersymmetric vacua and then raises the cosmological constant by modifying the compactification. As one raises the cosmological constant, the couplings typically destabilize the classically stable vacuum, so the probability that this approach will lead to a classically stable de-Sitter vacuum is Gaussianly suppressed. This implies that classically stable de-Sitter vacua in string theory (at least in the Type IIA region), especially those with relatively high cosmological constants, are very rare. The probability that a typical de-Sitter extremum is classically stable (i.e., tachyon-free) is argued to be Gaussianly suppressed as a function of the number of moduli.

  7. On the effective theory of type II string compactifications on nilmanifolds and coset spaces

    Caviezel, Claudio

    2009-07-30

    In this thesis we analyzed a large number of type IIA strict SU(3)-structure compactifications with fluxes and O6/D6-sources, as well as type IIB static SU(2)-structure compactifications with fluxes and O5/O7-sources. Restricting to structures and fluxes that are constant in the basis of left-invariant one-forms, these models are tractable enough to allow for an explicit derivation of the four-dimensional low-energy effective theory. The six-dimensional compact manifolds we studied in this thesis are nilmanifolds based on nilpotent Lie-algebras, and, on the other hand, coset spaces based on semisimple and U(1)-groups, which admit a left-invariant strict SU(3)- or static SU(2)-structure. In particular, from the set of 34 distinct nilmanifolds we identified two nilmanifolds, the torus and the Iwasawa manifold, that allow for an AdS{sub 4}, N = 1 type IIA strict SU(3)-structure solution and one nilmanifold allowing for an AdS{sub 4}, N = 1 type IIB static SU(2)-structure solution. From the set of all the possible six-dimensional coset spaces, we identified seven coset spaces suitable for strict SU(3)-structure compactifications, four of which also allow for a static SU(2)-structure compactification. For all these models, we calculated the four-dimensional low-energy effective theory using N = 1 supergravity techniques. In order to write down the most general four-dimensional effective action, we also studied how to classify the different disconnected ''bubbles'' in moduli space. (orig.)

  8. Mild to severe social fears: ranking types of feared social situations using item response theory.

    Crome, Erica; Baillie, Andrew

    2014-06-01

    Social anxiety disorder is one of the most common mental disorders, and is associated with long term impairment, distress and vulnerability to secondary disorders. Certain types of social fears are more common than others, with public speaking fears typically the most prevalent in epidemiological surveys. The distinction between performance- and interaction-based fears has been the focus of long-standing debate in the literature, with evidence performance-based fears may reflect more mild presentations of social anxiety. This study aims to explicitly test whether different types of social fears differ in underlying social anxiety severity using item response theory techniques. Different types of social fears were assessed using items from three different structured diagnostic interviews in four different epidemiological surveys in the United States (n=2261, n=5411) and Australia (n=1845, n=1497); and ranked using 2-parameter logistic item response theory models. Overall, patterns of underlying severity indicated by different fears were consistent across the four samples with items functioning across a range of social anxiety. Public performance fears and speaking at meetings/classes indicated the lowest levels of social anxiety, with increasing severity indicated by situations such as being assertive or attending parties. Fears of using public bathrooms or eating, drinking or writing in public reflected the highest levels of social anxiety. Understanding differences in the underlying severity of different types of social fears has important implications for the underlying structure of social anxiety, and may also enhance the delivery of social anxiety treatment at a population level. PMID:24873885

  9. The early life origin theory in the development of cardiovascular disease and type 2 diabetes.

    Lindblom, Runa; Ververis, Katherine; Tortorella, Stephanie M; Karagiannis, Tom C

    2015-04-01

    Life expectancy has been examined from a variety of perspectives in recent history. Epidemiology is one perspective which examines causes of morbidity and mortality at the population level. Over the past few 100 years there have been dramatic shifts in the major causes of death and expected life length. This change has suffered from inconsistency across time and space with vast inequalities observed between population groups. In current focus is the challenge of rising non-communicable diseases (NCD), such as cardiovascular disease and type 2 diabetes mellitus. In the search to discover methods to combat the rising incidence of these diseases, a number of new theories on the development of morbidity have arisen. A pertinent example is the hypothesis published by David Barker in 1995 which postulates the prenatal and early developmental origin of adult onset disease, and highlights the importance of the maternal environment. This theory has been subject to criticism however it has gradually gained acceptance. In addition, the relatively new field of epigenetics is contributing evidence in support of the theory. This review aims to explore the implication and limitations of the developmental origin hypothesis, via an historical perspective, in order to enhance understanding of the increasing incidence of NCDs, and facilitate an improvement in planning public health policy. PMID:25270249

  10. A sufficient condition for de Sitter vacua in type IIB string theory

    Rummel, Markus

    2011-01-01

    We derive a sufficient condition for realizing meta-stable de Sitter vacua with small positive cosmological constant within type IIB string theory flux compactifications with spontaneously broken supersymmetry. There are a number of `lamp post' constructions of de Sitter vacua in type IIB string theory and supergravity. We show that one of them -- the method of `K\\"ahler uplifting' by F-terms from an interplay between non-perturbative effects and the leading $\\alpha'$-correction -- allows for a more general parametric understanding of the existence of de Sitter vacua. The result is a condition on the values of the flux induced superpotential and the topological data of the Calabi-Yau compactification, which guarantees the existence of a meta-stable de Sitter vacuum if met. Our analysis explicitly includes the stabilization of all moduli, i.e. the K\\"ahler, dilaton and complex structure moduli, by the interplay of the leading perturbative and non-perturbative effects at parametrically large volume.

  11. A sufficient condition for de Sitter vacua in type IIB string theory

    Rummel, Markus [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Westphal, Alexander [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2011-07-15

    We derive a sufficient condition for realizing meta-stable de Sitter vacua with small positive cosmological constant within type IIB string theory flux compactifications with spontaneously broken supersymmetry. There are a number of 'lamp post' constructions of de Sitter vacua in type IIB string theory and supergravity. We show that one of them - the method of 'Kaehler uplifting' by F-terms from an interplay between non-perturbative effects and the leading {alpha}'-correction - allows for a more general parametric understanding of the existence of de Sitter vacua. The result is a condition on the values of the flux induced superpotential and the topological data of the Calabi-Yau compactification, which guarantees the existence of a meta-stable de Sitter vacuum if met. Our analysis explicitly includes the stabilization of all moduli, i.e. the Kaehler, dilaton and complex structure moduli, by the interplay of the leading perturbative and non-perturbative effects at parametrically large volume. (orig.)

  12. A Yang-Mills Type Gauge Theory of Gravity and the Dark Matter and Dark Energy Problems

    Yang, Yi

    2012-01-01

    A Yang-Mills type gauge theory of gravity is shown to have a richer structure than the Einstein's General Theory of Relativity. This new structure can give an explanation of the form of the galactic rotation curves, of the amount of intergalactic gravitational lensing, and of the accelerating expansion of the Universe.

  13. Demonstration of a viable quantitative theory for interplanetary type II radio bursts

    Schmidt, J. M.; Cairns, Iver H.

    2016-03-01

    Between 29 November and 1 December 2013 the two widely separated spacecraft STEREO A and B observed a long lasting, intermittent, type II radio burst for the extended frequency range ≈ 4 MHz to 30 kHz, including an intensification when the shock wave of the associated coronal mass ejection (CME) reached STEREO A. We demonstrate for the first time our ability to quantitatively and accurately simulate the fundamental (F) and harmonic (H) emission of type II bursts from the higher corona (near 11 solar radii) to 1 AU. Our modeling requires the combination of data-driven three-dimensional magnetohydrodynamic simulations for the CME and plasma background, carried out with the BATS-R-US code, with an analytic quantitative kinetic model for both F and H radio emission, including the electron reflection at the shock, growth of Langmuir waves and radio waves, and the radiations propagation to an arbitrary observer. The intensities and frequencies of the observed radio emissions vary hugely by factors ≈ 106 and ≈ 103, respectively; the theoretical predictions are impressively accurate, being typically in error by less than a factor of 10 and 20 %, for both STEREO A and B. We also obtain accurate predictions for the timing and characteristics of the shock and local radio onsets at STEREO A, the lack of such onsets at STEREO B, and the z-component of the magnetic field at STEREO A ahead of the shock, and in the sheath. Very strong support is provided by these multiple agreements for the theory, the efficacy of the BATS-R-US code, and the vision of using type IIs and associated data-theory iterations to predict whether a CME will impact Earth's magnetosphere and drive space weather events.

  14. Simplifying the one loop five graviton amplitude in type IIB string theory

    Basu, Anirban

    2016-01-01

    We consider the D^8 R^5 and D^{10} R^5 terms in the low momentum expansion of the five graviton amplitude in type IIB string theory at one loop. They involve integrals of various modular graph functions over the fundamental domain of SL(2,Z). Unlike the graphs which arise in the four graviton amplitude or at lower orders in the momentum expansion of the five graviton amplitude where the links are given by scalar Green functions, there are several graphs for the D^8 R^5 and D^{10} R^5 terms where two of the links are each given by a derivative of the Green function. Starting with appropriate auxiliary diagrams, we show that these graphs can be expressed in terms of those which do not involve any derivatives. This results in considerable simplification of the amplitude.

  15. Adaptation of learning resources based on the MBTI theory of psychological types

    Amel Behaz

    2012-01-01

    Full Text Available Today, the resources available on the web increases significantly. The motivation for the dissemination of knowledge and their acquisition by learners is central to learning. However, learners show differences between the ways of learning that suits them best. The objective of the work presented in this paper is to study how it is possible to integrate models from cognitive theories and ontologies for the adaptation of educational resources. The goal is to provide the system capabilities to conduct reasoning on descriptions obtained in order to automatically adapt the resources to a learner according to his preferences. We rely on the model MBTI (Myers-Briggs Type Indicator for the consideration of learning styles of learners as a criterion for adaptation.

  16. Quantum field theories with spontaneous symmetry breaking in external gravitational fields of cosmological type

    This chapter argues that an effective mechanism of entropy generation may be provided by a first-order vacuum phase transition in Coleman-Weinberg-type theories. The existence of such a transition solves simultaneously the long-standing homogeneity, isotropy and flatness problems of the standard hot big bang cosmology. Topics considered include the effective potential in an external gravitational field, symmetry behavior in finite volume, the open cosmological model, the closed cosmological model, and entropy generation. The expansion rate of the Universe is assumed to be sufficiently low. It is demonstrated that in the cosmological models with the initial vacuum state, the gravitational field strongly affects the symmetry properties of all quantum-field models. Particle creation, vacuum polarization and the rearrangement of vacuum take place simultaneously at the early stage of evolution, all these phenomena being governed solely by the cosmological gravitational field

  17. Mirage models confront the LHC. II. Flux-stabilized type IIB string theory

    Kaufman, Bryan L.; Nelson, Brent D.

    2014-04-01

    We continue the study of a class of string-motivated effective supergravity theories in light of current data from the CERN Large Hadron Collider (LHC). In this installment we consider type IIB string theory compactified on a Calabi-Yau orientifold in the presence of fluxes, in the manner originally formulated by Kachru et al. We allow for a variety of potential uplift mechanisms and embeddings of the Standard Model field content into D3-and D7-brane configurations. We find that an uplift sector independent of the Kähler moduli, as is the case with anti-D3-branes, is inconsistent with data unless the matter and Higgs sectors are localized on D7 branes exclusively, or are confined to twisted sectors between D3-and D7-branes. We identify regions of parameter space for all possible D-brane configurations that remain consistent with Planck observations on the dark matter relic density and measurements of the CP-even Higgs mass at the LHC. Constraints arising from LHC searches at √s =8 TeV and the LUX dark matter detection experiment are discussed. The discovery prospects for the remaining parameter space at dark matter direct-detection experiments are described, and signatures for detection of superpartners at the LHC with √s =14 TeV are analyzed.

  18. Bianchi type I anisotropic universe and stability interacting ghost dark energy in Brans-Dicke theories

    Hossienkhani, Hossien

    2016-01-01

    A spatially homogeneous and anisotropic Bianchi type I universe has been studied with the ghost dark energy (GDE) in the framework of Brans-Dicke theory. For this purpose, we use the squared sound speed $v_s^2$ whose sign determines the stability of the model. At first, we obtain the equation of state parameter, $\\omega_\\Lambda$, the deceleration parameter $q$ and the evolution equation of the ghost dark energy. Then, we extend our study to the case of ghost dark energy in a non-isotropic and Brans-Dicke framework and find out that the transition of $\\omega_\\Lambda$ to the phantom regime can be more easily accounted for than when it is restored into the Einstein field equations. Our numerical result show the effects of the interaction and anisotropic on the evolutionary behaviour the ghost dark energy models. In conclusion, we find evidence that the ghost dark energy in BD theory can lead to a stable universe favored by observations at the present time.

  19. Bianchi type I Universe and instability of new agegraphic dark energy in Brans-Dicke theories

    Fayaz, V.

    2016-02-01

    In this paper, we consider the new agegraphic dark energy (NADE) in a Bianchi type-I metric (which is a spatially homogeneous and anisotropic) in the framework of Brans-Dicke theory. For this purpose, we use the squared sound speed vs2 whose sign determines the stability of the model. We explore the stability of this model in the presence/absence of interaction between dark energy and dark matter in both flat and non-isotropic geometry. The equation of state and the deceleration parameter of the new agegraphic dark energy in a anisotropic Universe is obtained. We show that the combination of Brans-Dicke field and new agegraphic dark energy can accommodate ω_{\\varLambda}=-1 crossing for the equation of state of noninteracting dark energy. When an interaction between dark energy and dark matter is taken into account, the transition of ω_{\\varLambda} to phantom regime can be more easily accounted when the Einstein field equations is being resort. In conclusion, we find evidences that the new agegraphic dark energy in BD theory can not lead to a stable Universe favored by observations at the present time. The anisotropy of the Universe decreases and the Universe transits to an isotropic flat FRW Universe accommodating the present acceleration.

  20. Constraining f(R) theories with Type Ia Supernovae and Gamma Ray Bursts

    Cardone, Vincenzo F; Camera, Stefano

    2009-01-01

    Fourth - order gravity theories have received much interest in recent years thanks to their ability to provide an accelerated cosmic expansion in a matter only universe. In these theories, the Lagrangian density of the gravitational field has the form R + f(R), and the explicit choice of the arbitrary function f(R) must meet the local tests of gravity and the constraints from the primordial abundance of the light elements. Two popular classes of f(R) models, which are expected to fulfill all the above requirements, have recently been proposed. However, neither of these models has ever been quantitatively tested against the available astrophysical data. Here, by combining Type Ia Supernovae and Gamma Ray Bursts, we investigate the ability of these models to reproduce the observed Hubble diagram over the redshift range (0, 7). We find that both models fit very well this dataset with the present day values of the matter density and deceleration parameters which agree with previous estimates. However, the strong ...

  1. Mirage Models Confront the LHC: II. Flux-Stabilized Type IIB String Theory

    Kaufman, Bryan

    2013-01-01

    We continue the study of a class of string-motivated effective supergravity theories in light of current data from the CERN Large Hadron Collider (LHC). In this installment we consider Type IIB string theory compactified on a Calabi-Yau orientifold in the presence of fluxes, in the manner originally formulated by Kachru, et al. We allow for a variety of potential uplift mechanisms and embeddings of the Standard Model field content into D3 and D7 brane configurations. We find that an uplift sector independent of the Kahler moduli, as is the case with anti-D3 branes, is inconsistent with data unless the matter and Higgs sectors are localized on D7 branes exclusively, or are confined to twisted sectors between D3 and D7 branes. We identify regions of parameter space for all possible D-brane configurations that remain consistent with PLANCK observations on the dark matter relic density and measurements of the CP-even Higgs mass at the LHC. Constraints arising from LHC searches at 8 TeV center-of-mass energies, an...

  2. Engineering of Quantum Hall Effect from Type IIA String Theory on The K3 Surface

    Belhaj, Adil

    2010-01-01

    Using D-brane configurations on the K3 surface, we give six dimensional type IIA stringy realizations of the Quantum Hall Effect (QHE) in 1+2 dimensions. Based on the vertical and horizontal lines of the K3 Hodge diamond, we engineer two different stringy realizations. The vertical line presents a realization in terms of D2 and D6-branes wrapping the K3 surface. The horizontal one is associated with hierarchical stringy descriptions obtained from a quiver gauge theory living on a stack of D4-branes wrapping intersecting 2-spheres embedded in the K3 surface with deformed singularities. These geometries are classified by three kinds of the Kac-Moody algebras: ordinary, i.e finite dimensional, affine and indefinite. We find that no stringy QHE in 1+2 dimensions can occur in the quiver gauge theory living on intersecting 2-spheres arranged as affine Dynkin diagrams. Stringy realizations of QHE can be done only for the finite and indefinite geometries. In particular, the finite Lie algebras give models with fracti...

  3. Cultivating New-type Farmers Based on the Theory of Human Resources Development

    2010-01-01

    Under the direction of theory of human resources development,this thesis analyzes the impact of rural human resources development oncultivating new-type farmers.Firstly,it increases the input of rural basic education;secondly,it reinforces the vocational education and technologytraining;thirdly,it promotes the rural medical and public health services;fourthly,it quickens the rural labor transfer.The status quo of China’s ruralhuman resources has been analyzed as follows:in terms of the quantity of rural human resources,the status quo is large and quick-developed baseof rural human resources,high labor participatory rate,and constitution of low age;in terms of the quality of rural human resources,the status quois the ubiquitous low quality of rural human resources,low technological level of rural human resources,and overall low physical quality of farmers;in terms of the structure of rural human resources,the status quo is the irrational industrial structure distribution and imbalanced regional structuredistribution.The thesis also discusses the edification of theory of human resources development in cultivating new-type farmers.First,in terms ofthe control over quantity of rural human resources,it is to keep the stability of family planning policy,and expedite the transfer of rural surplus la-bor;second,in terms of promoting the quality of rural human resources,it is to bolster the development of reserve rural labor force resources,toconstruct the adult educational training system with Chinese characteristics,and to build rural primary health care system;third,in terms of adjus-ting the structure of rural human resources,it is to perfect rural human resources market,and adjust rural economical structure and talents struc-ture.

  4. Topological and geometrical quantum computation in cohesive Khovanov homotopy type theory

    Ospina, Juan

    2015-05-01

    The recently proposed Cohesive Homotopy Type Theory is exploited as a formal foundation for central concepts in Topological and Geometrical Quantum Computation. Specifically the Cohesive Homotopy Type Theory provides a formal, logical approach to concepts like smoothness, cohomology and Khovanov homology; and such approach permits to clarify the quantum algorithms in the context of Topological and Geometrical Quantum Computation. In particular we consider the so-called "open-closed stringy topological quantum computer" which is a theoretical topological quantum computer that employs a system of open-closed strings whose worldsheets are open-closed cobordisms. The open-closed stringy topological computer is able to compute the Khovanov homology for tangles and for hence it is a universal quantum computer given than any quantum computation is reduced to an instance of computation of the Khovanov homology for tangles. The universal algebra in this case is the Frobenius Algebra and the possible open-closed stringy topological quantum computers are forming a symmetric monoidal category which is equivalent to the category of knowledgeable Frobenius algebras. Then the mathematical design of an open-closed stringy topological quantum computer is involved with computations and theorem proving for generalized Frobenius algebras. Such computations and theorem proving can be performed automatically using the Automated Theorem Provers with the TPTP language and the SMT-solver Z3 with the SMT-LIB language. Some examples of application of ATPs and SMT-solvers in the mathematical setup of an open-closed stringy topological quantum computer will be provided.

  5. Critical phenomena in dynamical Ising-typed thin films by effective-field theory

    The stationary state solutions of the Ising-typed thin films with different layers in the presence of an external oscillatory field are examined within the effective-field theory. The study focuses on the effects of external field frequency and amplitude on the overall behavior. Particular attention is paid on evolution of the special point with dynamic field frequency corresponding to critical temperature of the three-dimensional infinite bulk system where the surface and modified exchange parameters are of no importance. Some findings such as surface enhancement phenomenon and effect of thickness on the dynamic process are introduced together with some other well known characteristics. An attempt is made to explain the relations between the competing time scales (intrinsic microscopic relaxation time of the system and the time period of the external oscillatory field) and frequency dispersion of the critical temperature coordinate of the special point. - Highlights: • Dynamical ferromagnetic Ising-type thin films were examined. • Variation of dynamical order parameters with temperature was plotted. • The profiles of average magnetizations on each layer were presented. • Dynamic phase boundaries were plotted in related planes. • The frequency dispersion of the related coordinate of special point was propounded

  6. A Review of Different Types of Subsidies and How They Work in Theory

    Kampungu; K.Gerson; Han; Feng

    2013-01-01

    This paper gives a brief review on types of subsidies and how they work in theory.The paper identified three types of subsidies:subsidies that increase revenue,subsidies that lower the cost of production,and subsidies that are not linked to production or input.With the use of graphic examples to describe the partial effects of subsidies on supply and demand,the following findings were obtained:one,for producers to sell more,they will need to produce more,and in order to produce more,a higher input level is required,which depends on the marginal productivity of the inputs;two,the larger the elasticity for supply and demand of input(the more responsive supply and demand are to changes in the price of the input),the larger quantity of input used for a given level of support,and thereby increasing the associated environmental damage from the use of that particular input;three,for a given demand curve,a shallow supply curve(reflecting a large price elasticity of supply)will yield larger volume effects in response to a certain change in price compared to a steep supply curve and vise a verse.Finally,the study found input subsidy as an example of subsidies that lower the cost of production,and direct income support or unconditional lump sum support to an industry as an example of subsidies that are not linked to production or input.

  7. Understanding physical activity intentions among French Canadians with type 2 diabetes: an extension of Ajzen's theory of planned behaviour

    Godin Gaston; Boudreau François

    2009-01-01

    Abstract Background Regular physical activity is considered a cornerstone for managing type 2 diabetes. However, in Canada, most individuals with type 2 diabetes do not meet national physical activity recommendations. When designing a theory-based intervention, one should first determine the key determinants of physical activity for this population. Unfortunately, there is a lack of information on this aspect among adults with type 2 diabetes. The purpose of this cross-sectional study is to f...

  8. Campbelling-type theory of fission chamber signals generated by neutron chains in a multiplying medium

    The signals of fission chambers are usually evaluated with the help of the co-called Campbelling techniques. These are based on the Campbell theorem, which states that if the primary incoming events, generating the detector pulses, are independent, then relationships exist between the moments of various orders of the signal in the current mode. This gives the possibility to determine the mean value of the intensity of the detection events, which is proportional to the static flux, from the higher moments of the detector current, which has certain advantages. However, the main application area of fission chambers is measurements in power reactors where, as is well known, the individual detection events are not independent, due to the branching character of the neutron chains (neutron multiplication). Therefore it is of interest to extend the Campbelling-type theory for the case of correlated neutron events. Such a theory could address two questions: partly, to investigate the bias when the traditional Campbell techniques are used for correlated incoming events; and partly, to see whether the correlation properties of the detection events, which carry information on the multiplying medium, could be extracted from the measurements. This paper is devoted to the investigation of these questions. The results show that there is a potential possibility to extract the same information from fission chamber signals in the current mode as with the Rossi- or Feynman-alpha methods, or from coincidence and multiplicity measurements, which so far have required detectors working in the pulse mode. It is also shown that application of the standard Campbelling techniques to neutron detection in multiplying systems does not lead to an error for estimating the stationary flux as long as the detector is calibrated in in situ measurements

  9. Non-perturbative black holes in Type-IIA String Theory versus the No-Hair conjecture

    We obtain the first black hole solution to Type-IIA String Theory compactified on an arbitrary self-mirror Calabi–Yau manifold in the presence of non-perturbative quantum corrections. Remarkably enough, the solution involves multivalued functions, which could lead to a violation of the No-Hair conjecture. We discuss how String Theory forbids such scenario. However, the possibility still remains open in the context of four-dimensional ungauged Supergravity. (paper)

  10. (2,2) and (0,4) Supersymmetric Boundary Conditions in 3d N = 4 Theories and Type IIB Branes

    Chung, Hee-Joong

    2016-01-01

    The half-BPS boundary conditions preserving N = (2,2) and N = (0,4) supersymmetry in 3d N = 4 supersymmetric gauge theories are examined. The BPS equations admit decomposition of the bulk supermultiplets into specific boundary supermultiplets of preserved supersymmetry. Bogomolony-like equations and Nahm-like equations arise in the vector multiplet BPS boundary conditions and Robin-type boundary conditions appear for the hypermultiplet coupled to vector multiplet. The half-BPS boundary conditions are realized in the brane configurations of Type IIB string theory.

  11. Chern class identities from tadpole matching in type IIB and F-theory

    In light of Sen's weak coupling limit of F-theory as a type IIB orientifold, the compatibility of the tadpole conditions leads to a non-trivial identity relating the Euler characteristics of an elliptically fibered Calabi-Yau fourfold and of certain related surfaces. We present the physical argument leading to the identity, and a mathematical derivation of a Chern class identity which confirms it, after taking into account singularities of the relevant loci. This identity of Chern classes holds in arbitrary dimension, and for varieties that are not necessarily Calabi-Yau. Singularities are essential in both the physics and the mathematics arguments: the tadpole relation may be interpreted as an identity involving stringy invariants of a singular hypersurface, and corrections for the presence of pinch-points. The mathematical discussion is streamlined by the use of Chern-Schwartz-MacPherson classes of singular varieties. We also show how the main identity may be obtained by applying 'Verdier specialization' to suitable constructible functions.

  12. From Peierls brackets to a generalized Moyal bracket for type-I gauge theories

    Esposito, G; Esposito, Giampiero; Stornaiolo, Cosimo

    2006-01-01

    In the space-of-histories approach to gauge fields and their quantization, the Maxwell, Yang--Mills and gravitational field are well known to share the property of being type-I theories, i.e. Lie brackets of the vector fields which leave the action functional invariant are linear combinations of such vector fields, with coefficients of linear combination given by structure constants. The corresponding gauge-field operator in the functional integral for the in-out amplitude is an invertible second-order differential operator. For such an operator, we consider advanced and retarded Green functions giving rise to a Peierls bracket among group-invariant functionals. Our Peierls bracket is a Poisson bracket on the space of all group-invariant functionals in two cases only: either the gauge-fixing is arbitrary but the gauge fields lie on the dynamical sub-space; or the gauge-fixing is a linear functional of gauge fields, which are generic points of the space of histories. In both cases, the resulting Peierls bracke...

  13. Psychosocial correlates of dietary behaviour in type 2 diabetic women, using a behaviour change theory.

    Didarloo, A; Shojaeizadeh, D; Gharaaghaji Asl, R; Niknami, S; Khorami, A

    2014-06-01

    The study evaluated the efficacy of the Theory of Reasoned Action (TRA), along with self-efficacy to predict dietary behaviour in a group of Iranian women with type 2 diabetes. A sample of 352 diabetic women referred to Khoy Diabetes Clinic, Iran, were selected and given a self-administered survey to assess eating behaviour, using the extended TRA constructs. Bivariate correlations and Enter regression analyses of the extended TRA model were performed with SPSS software. Overall, the proposed model explained 31.6% of variance of behavioural intention and 21.5% of variance of dietary behaviour. Among the model constructs, self-efficacy was the strongest predictor of intentions and dietary practice. In addition to the model variables, visit intervals of patients and source of obtaining information about diabetes from sociodemographic factors were also associated with dietary behaviours of the diabetics. This research has highlighted the relative importance of the extended TRA constructs upon behavioural intention and subsequent behaviour. Therefore, use of the present research model in designing educational interventions to increase adherence to dietary behaviours among diabetic patients was recommended and emphasized. PMID:25076670

  14. Algebraic Signal Processing Theory: Cooley-Tukey Type Algorithms for Polynomial Transforms Based on Induction

    Sandryhaila, Aliaksei; Pueschel, Markus

    2010-01-01

    A polynomial transform is the multiplication of an input vector $x\\in\\C^n$ by a matrix $\\PT_{b,\\alpha}\\in\\C^{n\\times n},$ whose $(k,\\ell)$-th element is defined as $p_\\ell(\\alpha_k)$ for polynomials $p_\\ell(x)\\in\\C[x]$ from a list $b=\\{p_0(x),\\dots,p_{n-1}(x)\\}$ and sample points $\\alpha_k\\in\\C$ from a list $\\alpha=\\{\\alpha_0,\\dots,\\alpha_{n-1}\\}$. Such transforms find applications in the areas of signal processing, data compression, and function interpolation. Important examples include the discrete Fourier and cosine transforms. In this paper we introduce a novel technique to derive fast algorithms for polynomial transforms. The technique uses the relationship between polynomial transforms and the representation theory of polynomial algebras. Specifically, we derive algorithms by decomposing the regular modules of these algebras as a stepwise induction. As an application, we derive novel $O(n\\log{n})$ general-radix algorithms for the discrete Fourier transform and the discrete cosine transform of type 4.

  15. MAMA Software Features: Visual Examples of Quantification

    Ruggiero, Christy E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Porter, Reid B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-05-20

    This document shows examples of the results from quantifying objects of certain sizes and types in the software. It is intended to give users a better feel for some of the quantification calculations, and, more importantly, to help users understand the challenges with using a small set of ‘shape’ quantification calculations for objects that can vary widely in shapes and features. We will add more examples to this in the coming year.

  16. Semi-quantification of endolymphatic size on MR imaging after intravenous injection of single-dose gadodiamide. Comparison between two types of processing strategies

    Many inner ear disorders, including Meniere's disease, are believed to be based on endolymphatic hydrops. We evaluated a newly proposed method for semi-quantification of endolymphatic size in patients with suspected endolymphatic hydrops that uses 2 kinds of processed magnetic resonance (MR) images. Twenty-four consecutive patients underwent heavily T2-weighted (hT2W) MR cisternography (MRC), hT2W 3-dimensional (3D) fluid-attenuated inversion recovery (FLAIR) with inversion time of 2250 ms (positive perilymph image, PPI), and hT2W-3D-IR with inversion time of 2050 ms (positive endolymph image, PEI) 4 hours after intravenous administration of single-dose gadolinium-based contrast material (IV-SD-GBCM). Two images were generated using 2 new methods to process PPI, PEI, and MRC. Three radiologists contoured the cochlea and vestibule on MRC, copied regions of interest (ROIs) onto the 2 kinds of generated images, and semi-quantitatively measured the size of the endolymph for the cochlea and vestibule by setting a threshold pixel value. Each observer noted a strong linear correlation between endolymphatic size of both the cochlea and vestibule of the 2 kinds of generated images. The Pearson correlation coefficients (r) were 0.783, 0.734, and 0.800 in the cochlea and 0.924, 0.930, and 0.933 in the vestibule (P<0.001, for all). In both the cochlea and vestibule, repeated-measures analysis of variance showed no statistically significant difference between observers. Use of the 2 kinds of generated images generated from MR images obtained 4 hours after IV-SD-GBCM might enable semi-quantification of endolymphatic size with little observer dependency. (author)

  17. Kendall's Shape Statistics as a Classical Realization of Barbour-type Timeless Records Theory approach to Quantum Gravity

    Anderson, Edward

    2013-01-01

    I already showed that Kendall's shape geometry work was the geometrical description of Barbour's relational mechanics' reduced configuration spaces (alias shape spaces). I now describe the extent to which Kendall's subsequent statistical application to such as the `standing stones problem' realizes further ideas along the lines of Barbour-type timeless records theories, albeit just at the classical level.

  18. Kendall's Shape Statistics as a Classical Realization of Barbour-type Timeless Records Theory approach to Quantum Gravity

    Anderson, Edward

    2013-01-01

    I previously showed that Kendall's work on shape geometry is in fact also the geometrical description of Barbour's relational mechanics' reduced configuration spaces (alias shape spaces). I now describe the extent to which Kendall's subsequent statistical application to e.g. the `standing stones problem' realizes further ideas along the lines of Barbour-type timeless records theories, albeit just at the classical level.

  19. Theory and experiment of an inertia-type vertical isolation system for seismic protection of equipment

    Lu, Lyan-Ywan; Chen, Pei-Rong; Pong, Kuan-Wen

    2016-03-01

    Although it has been proven that seismic isolation is an effective technology for seismic protection of structures and equipment, most existing isolation systems are for mitigating horizontal ground motions, and in practice there are very few vertical isolation systems. Part of the reason is due to the conflict with regard to the demand for isolation stiffness. In other words, a vertical isolation system must have sufficient vertical rigidity to sustain the weight of the isolated object, while it must also have sufficient flexibility in order to elongate the vibration period under seismic excitation. In order to overcome this difficulty, a novel system is proposed in this study, called an inertia-type vertical isolation system (IVIS). The primary difference between the IVIS and a traditional system is that the former has an additional leverage mechanism with a counterweight. The counterweight will provide a static uplifting force and an extra dynamic inertia force, such that the effective vertical stiffness of the IVIS becomes higher in its static state and lower in the dynamic one. The theory underlying the IVIS is developed and verified experimentally by a seismic simulation test in this work. The results show that the IVIS leads to a less static settlement and at the same time a lower effective isolation frequency. The test results also demonstrate that the isolator displacement demand of the IVIS is only about 30-40 percent that of the traditional one in all kinds of earthquakes. With regard to the reduction of acceleration response, the IVIS is particularly effective for near-fault earthquakes or near-resonant excitations, but is less effective for far-field earthquakes with more high-frequency contents, as compared with the traditional system.

  20. Quantification of human responses

    Steinlage, R. C.; Gantner, T. E.; Lim, P. Y. W.

    1992-01-01

    Human perception is a complex phenomenon which is difficult to quantify with instruments. For this reason, large panels of people are often used to elicit and aggregate subjective judgments. Print quality, taste, smell, sound quality of a stereo system, softness, and grading Olympic divers and skaters are some examples of situations where subjective measurements or judgments are paramount. We usually express what is in our mind through language as a medium but languages are limited in available choices of vocabularies, and as a result, our verbalizations are only approximate expressions of what we really have in mind. For lack of better methods to quantify subjective judgments, it is customary to set up a numerical scale such as 1, 2, 3, 4, 5 or 1, 2, 3, ..., 9, 10 for characterizing human responses and subjective judgments with no valid justification except that these scales are easy to understand and convenient to use. But these numerical scales are arbitrary simplifications of the complex human mind; the human mind is not restricted to such simple numerical variations. In fact, human responses and subjective judgments are psychophysical phenomena that are fuzzy entities and therefore difficult to handle by conventional mathematics and probability theory. The fuzzy mathematical approach provides a more realistic insight into understanding and quantifying human responses. This paper presents a method for quantifying human responses and subjective judgments without assuming a pattern of linear or numerical variation for human responses. In particular, quantification and evaluation of linguistic judgments was investigated.

  1. Advances in type-2 fuzzy sets and systems theory and applications

    Mendel, Jerry; Tahayori, Hooman

    2013-01-01

    This book explores recent developments in the theoretical foundations and novel applications of general and interval type-2 fuzzy sets and systems, including: algebraic properties of type-2 fuzzy sets, geometric-based definition of type-2 fuzzy set operators, generalizations of the continuous KM algorithm, adaptiveness and novelty of interval type-2 fuzzy logic controllers, relations between conceptual spaces and type-2 fuzzy sets, type-2 fuzzy logic systems versus perceptual computers; modeling human perception of real world concepts with type-2 fuzzy sets, different methods for generating membership functions of interval and general type-2 fuzzy sets, and applications of interval type-2 fuzzy sets to control, machine tooling, image processing and diet.  The applications demonstrate the appropriateness of using type-2 fuzzy sets and systems in real world problems that are characterized by different degrees of uncertainty.

  2. Elastic properties of lotus-type porous iron: acoustic measurement and extended effective-mean-field theory

    We studied the elastic properties of lotus-type porous iron experimentally and theoretically. First we determined the elastic constants of lotus iron fabricated by the continuous zone-melting method by using the acoustic resonance techniques. All the elastic moduli are found to follow the well-known power-law formula. Next, we extended the effective-mean-field (EMF) theory so as to consider effects of the pore orientation on the effective elastic constants. The model calculations proved that the extended EMF theory is capable of calculating satisfactorily the elastic properties of lotus metals

  3. Two types of conservation laws. Connection of physical fields with material systems. Peculiarities of field theories

    Petrova, L I

    2008-01-01

    Historically it happen so that in branches of physics connected with field theory and of physics of material systems (continuous media) the concept of "conservation laws" has a different meaning. In field theory "conservation laws" are those that claim the existence of conservative physical quantities or objects. These are conservation laws for physical fields. In contrast to that in physics (and mechanics) of material systems the concept of "conservation laws" relates to conservation laws for energy, linear momentum, angular momentum, and mass that establish the balance between the change of physical quantities and external action. In the paper presented it is proved that there exist a connection between of conservation laws for physical fields and those for material systems. This points to the fact that physical fields are connected with material systems. Such results has an unique significance for field theories. This enables one to substantiate many basic principles of field theories, such as, for example...

  4. Spectral analysis of polynomial potentials and its relation with ABJ/M-type theories

    We obtain a general class of polynomial potentials for which the Schroedinger operator has a discrete spectrum. This class includes all the scalar potentials in membrane, 5-brane, p-branes, multiple M2 branes, BLG and ABJM theories. We provide a proof of the discreteness of the spectrum of the associated Schroedinger operators. This is the first step in order to analyze BLG and ABJM supersymmetric theories from a non-perturbative point of view.

  5. Spectral analysis of polynomial potentials and its relation with ABJ/M-type theories

    Garcia del Moral, M.P., E-mail: garciamormaria@uniovi.e [Departamento de Fisica, Universidad de Oviedo, Calvo Sotelo 18, 33007 Oviedo (Spain); Martin, I., E-mail: isbeliam@usb.v [Departamento de Fisica, Universidad Simon Bolivar, Apartado 89000, Caracas 1080-A (Venezuela, Bolivarian Republic of); Navarro, L., E-mail: lnavarro@ma.usb.v [Departamento de Matematicas, Universidad Simon Bolivar, Apartado 89000, Caracas 1080-A (Venezuela, Bolivarian Republic of); Perez, A.J., E-mail: ajperez@ma.usb.v [Departamento de Matematicas, Universidad Simon Bolivar, Apartado 89000, Caracas 1080-A (Venezuela, Bolivarian Republic of); Restuccia, A., E-mail: arestu@usb.v [Departamento de Fisica, Universidad Simon Bolivar, Apartado 89000, Caracas 1080-A (Venezuela, Bolivarian Republic of)

    2010-11-01

    We obtain a general class of polynomial potentials for which the Schroedinger operator has a discrete spectrum. This class includes all the scalar potentials in membrane, 5-brane, p-branes, multiple M2 branes, BLG and ABJM theories. We provide a proof of the discreteness of the spectrum of the associated Schroedinger operators. This is the first step in order to analyze BLG and ABJM supersymmetric theories from a non-perturbative point of view.

  6. Exact combinatorics of Bern-Kosower-type amplitudes for two-loop Φ3 theory

    Counting the contribution rate of a world-line formula to Feynman diagrams in φ3 theory, we explain the idea of how to determine precise combinatorics of Bern-Kosower-like amplitudes derived from a bosonic string theory for N-point two-loop Feynman amplitudes. In this connection we also present a method to derive simple and compact world-line forms for the effective action. (orig.)

  7. Two types of conservation laws. Connection of physical fields with material systems. Peculiarities of field theories

    Petrova, L. I.

    2008-01-01

    Historically it happen so that in branches of physics connected with field theory and of physics of material systems (continuous media) the concept of "conservation laws" has a different meaning. In field theory "conservation laws" are those that claim the existence of conservative physical quantities or objects. These are conservation laws for physical fields. In contrast to that in physics (and mechanics) of material systems the concept of "conservation laws" relates to conservation laws fo...

  8. Fitting the luminosity data from type Ia supernovae in the frame of the Cosmic Defect theory

    Tartaglia, A; Cardone, V; Radicella, N

    2008-01-01

    The Cosmic Defect (CD) theory is reviewed and used to fit the data for the accelerated expansion of the universe, obtained from the apparent luminosity of 192 SnIa's. The fit from CD is compared with the one obtained by means of $\\Lambda $CDM. The results from both theories are in good agreement and the fits are satisfactory. The correspondence between both approaches is discussed and interpreted.

  9. Landauer-type transport theory for interacting quantum wires: Application to carbon nanotube Y junctions

    Chen, S.; Trauzettel, B.; Egger, R.

    2002-01-01

    We propose a Landauer-like theory for nonlinear transport in networks of one-dimensional interacting quantum wires (Luttinger liquids). A concrete example of current experimental focus is given by carbon nanotube Y junctions. Our theory has three basic ingredients that allow to explicitly solve this transport problem: (i) radiative boundary conditions to describe the coupling to external leads, (ii) the Kirchhoff node rule describing charge conservation, and (iii) density matching conditions ...

  10. Landauer-Type Transport Theory for Interacting Quantum Wires: Application to Carbon Nanotube Y Junctions

    Chen, S.; Trauzettel, B.; Egger, R.

    2002-11-01

    We propose a Landauerlike theory for nonlinear transport in networks of one-dimensional interacting quantum wires (Luttinger liquids). A concrete example of current experimental focus is given by carbon nanotube Y junctions. Our theory has three basic ingredients that allow one to explicitly solve this transport problem: (i) radiative boundary conditions to describe the coupling to external leads, (ii) the Kirchhoff node rule describing charge conservation, and (iii) density matching conditions at every node.

  11. Extension Theory and Krein-type Resolvent Formulas for Nonsmooth Boundary Value Problems

    Abels, Helmut; Grubb, Gerd; Wood, Ian Geoffrey

    2014-01-01

    The theory of selfadjoint extensions of symmetric operators, and more generally the theory of extensions of dual pairs, was implemented some years ago for boundary value problems for elliptic operators on smooth bounded domains. Recently, the questions have been taken up again for nonsmooth domai...... analyze resolvents, Poisson solution operators and Dirichlet-to-Neumann operators in this way, also in Sobolev spaces of negative order....

  12. Understanding physical activity intentions among French Canadians with type 2 diabetes: an extension of Ajzen's theory of planned behaviour

    Boudreau, François; Godin, Gaston

    2009-01-01

    Background Regular physical activity is considered a cornerstone for managing type 2 diabetes. However, in Canada, most individuals with type 2 diabetes do not meet national physical activity recommendations. When designing a theory-based intervention, one should first determine the key determinants of physical activity for this population. Unfortunately, there is a lack of information on this aspect among adults with type 2 diabetes. The purpose of this cross-sectional study is to fill this gap using an extended version of Ajzen's Theory of Planned Behavior (TPB) as reference. Methods A total of 501 individuals with type 2 diabetes residing in the Province of Quebec (Canada) completed the study. Questionnaires were sent and returned by mail. Results Multiple hierarchical regression analyses indicated that TPB variables explained 60% of the variance in intention. The addition of other psychosocial variables in the model added 7% of the explained variance. The final model included perceived behavioral control (β = .38, p < .0001), moral norm (β = .29, p < .0001), and attitude (β = .14, p < .01). Conclusion The findings suggest that interventions aimed at individuals with type 2 diabetes should ensure that people have the necessary resources to overcome potential obstacles to behavioral performance. Interventions should also favor the development of feelings of personal responsibility to exercise and promote the advantages of exercising for individuals with type 2 diabetes. PMID:19531261

  13. Understanding physical activity intentions among French Canadians with type 2 diabetes: an extension of Ajzen's theory of planned behaviour

    Godin Gaston

    2009-06-01

    Full Text Available Abstract Background Regular physical activity is considered a cornerstone for managing type 2 diabetes. However, in Canada, most individuals with type 2 diabetes do not meet national physical activity recommendations. When designing a theory-based intervention, one should first determine the key determinants of physical activity for this population. Unfortunately, there is a lack of information on this aspect among adults with type 2 diabetes. The purpose of this cross-sectional study is to fill this gap using an extended version of Ajzen's Theory of Planned Behavior (TPB as reference. Methods A total of 501 individuals with type 2 diabetes residing in the Province of Quebec (Canada completed the study. Questionnaires were sent and returned by mail. Results Multiple hierarchical regression analyses indicated that TPB variables explained 60% of the variance in intention. The addition of other psychosocial variables in the model added 7% of the explained variance. The final model included perceived behavioral control (β = .38, p Conclusion The findings suggest that interventions aimed at individuals with type 2 diabetes should ensure that people have the necessary resources to overcome potential obstacles to behavioral performance. Interventions should also favor the development of feelings of personal responsibility to exercise and promote the advantages of exercising for individuals with type 2 diabetes.

  14. Viscopolasticity theory based on overstress: The modeling of ratchetting and cyclic hardening of AISI type 304 stainless steel

    The small-strain, isotropic viscoplasticity theory based on overstress (VBO) is used. The theory is of the unified type and does not employ yield or loading/unloading criteria. The inelastic strain rate is a function of the overstress, the difference between the stress and the equilibrium stress, which is a state variable of the theory. Its growth law is the repository for modeling nearly elastic regions and hysteresis. Under constant strain rate loading, the theory admits asymptotic solutions, which show that the stress is composed of viscous, rate-independent (plastic) and kinematic contributions. For the modeling of cyclic hardening, a growth law for the rate-independent contribution to the stress is formulated. It models a different type of growth for proportional and nonproportional as well as cyclic and monotonic loadings. Numerical experiments for homogeneous states of stress are performed by intergrating the stiff, nonlinear ordinary differential equations using the IMSL routine DGEAR. They demonstrate the modeling capabilities for step-down and step-up two-amplitude loadings, for proportional and nonproportional cyclic loading including elliptical and square paths as well as for ratchetting. (orig./MM)

  15. Efficacy of an Intervention Based on the Theory of Planned Behavior on Foot Care Performance in Type II Diabetic Patients

    Beiranvand; Asadizaker; Fayazi; Yaralizadeh

    2015-01-01

    Background It is known that health education on foot care is a common strategy for preventing diabetic foot and reducing the rate of lower limb amputation. Objectives To evaluate the efficacy of an intervention based on the theory of planned behavior for improving foot care in patients with type II diabetes in 2013 in Ahvaz, Iran. Patients and Methods In this clinical trial, 69 pat...

  16. Microscopic entropy of the most general BPS black hole for type II/M-theory on torii

    In the present dissertation we review the statistical computation of the entropy for the most general static BPS black hole solution in the framework of toroidally compactified type II/M-theory. This achievement is inscribed within a research project aimed to the study of the microscopic properties of this kind of solutions in relation to U-duality invariants (e.g. the entropy) computed on the corresponding macroscopic (supergravity) description. (orig.)

  17. In situ wave phenomena in the upstream and downstream regions of interplanetary shocks: Implications for type 2 burst theories

    Thejappa, G.; MacDowall, R. J.; Vinas, A. F.

    1997-01-01

    The results are presented of in situ waves observed by the Ulyssess unified radio and plasma wave experiment (URAP) in the upstream and downstream regions of a large number of interplanetary shocks. The Langmuir waves which are the most essential ingredients for the type 2 radio emission are observed only in the upstream regions of a limited number of shocks. On the other hand, the ion-acoustic-like waves (0.5 to 5 kHz) are observed near most of the interplanetary shocks. Implications of observations made for the electron acceleration mechanisms at the collisionless shocks and for type 2 burst theories are presented.

  18. Inflation and Singularity of a Bianchi Type-Ⅶ0 Universe with a Dirac Field in the Einstein-Cartan Theory

    HUANG Zeng-Guang; FANG Wei; LU Hui-Qing

    2011-01-01

    @@ We discuss Bianchi type-Ⅶ0 cosmology with a Dirac field in the Einstein-Cartan(E-C) theory and obtain the equations of the Dirac and gravitational fields in the E-C theory.A Bianchi type-Ⅶ0 inflationary solution is found.When(3/16)S2-σ2>0, the Universe may avoid singularity.

  19. Comparison of two high-throughput assays for quantification of adenovirus type 5 neutralizing antibodies in a population of donors in China.

    Qiang Liu

    Full Text Available BACKGROUND: The presence of various levels of Adenovirus serotype 5 neutralizing antibodies (Ad5NAb is thought to contribute to the inconsistent clinical results obtained from vaccination and gene therapy studies. Currently, two platforms based on high-throughput technology are available for Ad5NAb quantification, chemiluminescence- and fluorescence-based assays. The aim of this study was to compare the results of two assays in the seroepidemiology of Ad5NAb in a local population of donors. METHODOLOGY/PRINCIPAL FINDINGS: The fluorescence-based neutralizing antibody detection test (FRNT using recombinant Ad5-EGFP virus and the chemiluminescence-based neutralizing antibody test (CLNT using Ad5-Fluc were developed and standardized for detecting the presence of Ad5NAb in serum samples from the population of donors in Beijing and Anhui provinces, China. First, the overall percentage of people positive for Ad5NAb performed by CLNT was higher than that obtained by FRNT (85.4 vs 69.9%, p<0.001. There was an 84.5% concordance between the two assays for the 206 samples tested (144 positive in both assays and 30 negative in both assays. All 32 discordant sera were CLNT-positive/FRNT-negative and were confirmed positive by western blot. Secondly, for all 144 sera positive by both assays, the two assays showed high correlation (r = 0.94, p<0.001 and close agreement (mean difference: 0.395 log(10, 95% CI: -0.054 log(10 to 0.845 log(10. Finally, it was found by both assays that there was no significant difference observed for titer or prevalence by gender (p = 0.503 vs 0.818, for two assays; however, age range (p = 0.049 vs 0.010 and geographic origin (p = 0.007 vs 0.011 were correlated with Ad5NAb prevalence in northern regions of China. CONCLUSION: The CLNT assay was relatively more simple and had higher sensitivity than the FRNT assay for determining Ad5NAb titers. It is strongly suggested that the CLNT assay be used for future

  20. Communication: Cosolvency and cononsolvency explained in terms of a Flory-Huggins type theory

    Standard Flory-Huggins (FH) theory is utilized to describe the enigmatic cosolvency and cononsolvency phenomena for systems of polymers dissolved in mixed solvents. In particular, phase boundaries (specifically upper critical solution temperature spinodals) are calculated for solutions of homopolymers B in pure solvents and in binary mixtures of small molecule liquids A and C. The miscibility (or immiscibility) patterns for the ternary systems are classified in terms of the FH binary interaction parameters (χαβ) and the ratio r = ϕA/ϕC of the concentrations ϕA and ϕC of the two solvents. The trends in miscibility are compared to those observed for blends of random copolymers (AxC1−x) with homopolymers (B) and to those deduced for A/B/C solutions of polymers B in liquid mixtures of small molecules A and C that associate into polymeric clusters (ApCq)i, (i = 1, 2, …, ∞). Although the classic FH theory is able to explain cosolvency and cononsolvency phenomena, the theory does not include a consideration of the mutual association of the solvent molecules and the competitive association between the solvent molecules and the polymer. These interactions can be incorporated in refinements of the FH theory, and the present paper provides a foundation for such extensions for modeling the rich thermodynamics of polymers in mixed solvents

  1. Communication: Cosolvency and cononsolvency explained in terms of a Flory-Huggins type theory

    Dudowicz, Jacek, E-mail: dudowicz@jfi.uchicago.edu; Freed, Karl F. [The James Franck Institute and the Department of Chemistry, The University of Chicago, Chicago, Illinois 60637 (United States); Douglas, Jack F. [Materials Science and Engineering Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 (United States)

    2015-10-07

    Standard Flory-Huggins (FH) theory is utilized to describe the enigmatic cosolvency and cononsolvency phenomena for systems of polymers dissolved in mixed solvents. In particular, phase boundaries (specifically upper critical solution temperature spinodals) are calculated for solutions of homopolymers B in pure solvents and in binary mixtures of small molecule liquids A and C. The miscibility (or immiscibility) patterns for the ternary systems are classified in terms of the FH binary interaction parameters (χ{sub αβ}) and the ratio r = ϕ{sub A}/ϕ{sub C} of the concentrations ϕ{sub A} and ϕ{sub C} of the two solvents. The trends in miscibility are compared to those observed for blends of random copolymers (A{sub x}C{sub 1−x}) with homopolymers (B) and to those deduced for A/B/C solutions of polymers B in liquid mixtures of small molecules A and C that associate into polymeric clusters (A{sub p}C{sub q}){sub i}, (i = 1, 2, …, ∞). Although the classic FH theory is able to explain cosolvency and cononsolvency phenomena, the theory does not include a consideration of the mutual association of the solvent molecules and the competitive association between the solvent molecules and the polymer. These interactions can be incorporated in refinements of the FH theory, and the present paper provides a foundation for such extensions for modeling the rich thermodynamics of polymers in mixed solvents.

  2. School Type and Academic Culture: Evidence for the Differentiation-Polarization Theory

    Van Houtte, Mieke

    2006-01-01

    Several decades ago it was shown that the differentiation of pupils into tracks and streams led to a polarization into "anti-school" and "pro-school" cultures. Support for this differentiation-polarization theory is mainly based on case studies. This paper presents findings of a quantitative study in Belgium (Flanders). Attention is given to the…

  3. Physical activity and diabetes: an application of the theory of planned behaviour to explain physical activity for Type 1 and Type 2 diabetes in an adult population sample.

    Plotnikoff, Ronald C; Lippke, Sonia; Courneya, Kerry; Birkett, Nicholas; Sigal, Ronald

    2010-01-01

    Physical activity (PA) plays a key role in the management of Type 1 (T1D) and Type 2 diabetes (T2D) but there are few theory-based, effective programs to promote PA for individuals with diabetes. The purpose of this study was to investigate the utility of the Theory of Planned Behaviour (TPB) in understanding PA in an adult population with T1D or T2D. A total of 2311 individuals (691 T1D; 1614 T2D) completed self-report TPB constructs of attitude, subjective norms, perceived behavioural control (PBC), intention and PA at baseline and 1717 (524 T1D; 1123 T2D) completed the PA measure again at 6-month follow-up. Multi-group Structural Equation Modelling was conducted to: (1) test the fit of the TPB structure (2) determine the TPB structural invariance between the two types of diabetes and (3) to examine the explained variances in PA and compare the strength of associations of the TPB constructs in the two types of diabetes. The TPB constructs explained > or =40% of the variance in intentions for both diabetes groups. In cross-sectional models, the TPB accounted for 23 and 19% of the variance in PA for T1D and T2D, respectively. In prospective models, the TPB explained 13 and 8% of the variance in PA for T1D and T2D, respectively. When adjusting for past PA behaviour, the impact of PBC and intention on behaviour was reduced in both groups. The findings provide evidence for the utility of the TPB for the design of PA promotion interventions for adults with either T1D or T2D. PMID:20391204

  4. Quantification of beta-cell function during IVGTT in Type II and non-diabetic subjects: assessment of insulin secretion by mathematical methods

    Kjems, L L; Vølund, A; Madsbad, Sten

    2001-01-01

    AIMS/HYPOTHESIS: We compared four methods to assess their accuracy in measuring insulin secretion during an intravenous glucose tolerance test in patients with Type II (non-insulin-dependent) diabetes mellitus and with varying beta-cell function and matched control subjects. METHODS: Eight control...... subjects and eight Type II diabetic patients underwent an intravenous glucose tolerance test with tolbutamide and an intravenous bolus injection of C-peptide to assess C-peptide kinetics. Insulin secretion rates were determined by the Eaton deconvolution (reference method), the Insulin SECretion method...... first-phase insulin response (r = 0.78). The two-compartment combined model failed to provide reliable estimates of insulin secretion in three of the control subjects and in two patients with Type II diabetes. The four methods were accurate with respect to mean basal and first-phase secretion response...

  5. Electrostatic field in superconductors IV: theory of Ginzburg-Landau type

    Lipavský, Pavel; Koláček, Jan

    2009-01-01

    Roč. 23, 20-21 (2009), s. 4505-4511. ISSN 0217-9792 R&D Projects: GA ČR GA202/04/0585; GA ČR GA202/05/0173; GA AV ČR IAA1010312 Institutional research plan: CEZ:AV0Z10100521 Keywords : superconductivity * Ginzburg-Landau theory Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.408, year: 2009

  6. Symmetry breaking and restoration for interacting scalar and gauge fields in Lifshitz type theories

    Farakos, K.; Metaxas, D.

    2012-05-01

    We consider the one-loop effective potential at zero and finite temperature in field theories with anisotropic space-time scaling, with critical exponent z = 2, including both scalar and gauge fields. Depending on the relative strength of the coupling constants for the gauge and scalar interactions, we find that there is a symmetry breaking term induced at one loop at zero temperature and we find symmetry restoration through a first-order phase transition at high temperature.

  7. Symmetry breaking and restoration for interacting scalar and gauge fields in Lifshitz type theories

    Farakos, K

    2011-01-01

    We consider the one-loop effective potential at zero and finite temperature in field theories with anisotropic space-time scaling, with critical exponent $z=2$, including both scalar and gauge fields. Depending on the relative strength of the coupling constants for the gauge and scalar interactions, we find that there is a symmetry breaking term induced at one-loop at zero temperature and we find symmetry restoration through a first-order phase transition at high temperature.

  8. Symmetry breaking and restoration for interacting scalar and gauge fields in Lifshitz type theories

    Farakos, K., E-mail: kfarakos@central.ntua.gr [Department of Physics, National Technical University of Athens, Zografou Campus, 15780 Athens (Greece); Metaxas, D., E-mail: metaxas@central.ntua.gr [Department of Physics, National Technical University of Athens, Zografou Campus, 15780 Athens (Greece)

    2012-05-01

    We consider the one-loop effective potential at zero and finite temperature in field theories with anisotropic space-time scaling, with critical exponent z=2, including both scalar and gauge fields. Depending on the relative strength of the coupling constants for the gauge and scalar interactions, we find that there is a symmetry breaking term induced at one loop at zero temperature and we find symmetry restoration through a first-order phase transition at high temperature.

  9. Type and structure of timelike singularities in the general theory of relativity: from the gamma metric to the general solution

    A method is proposed that makes it possible to determine whether a timelike singularity corresponds to a point, linear, or other type of gravitational field source. It is shown that in the general theory of relativity it is also possible to have sources of a quite different type with no analogs in a space of finite curvature. An analysis is made of some well-known solutions containing timelike singularities whose type varies depending on the signs of the functions that occur in the solutions. The form of the solution near simple linear sources [W. Israel, Phys. Rev. D15, 935 (1977)] and generalized anisotropic solutions [S. L. Parnovsky, Physica (Utrecht) 104A, 210 (1980); E. M. Lifshitz and I. M. Khalatnikov, Sov. Phys. Usp. 6, 359 (1963)] is determined more accurately; the space-time described by the γ metric (3) is completely investigated; and the form of the metric near the ends and singular points of linear Weyl singularities is found

  10. RENEWAL OF BASIC LAWS AND PRINCIPLES FOR POLAR CONTINUUM THEORIES(Ⅶ)-INCREMENTAL RATE TYPE

    戴安民

    2003-01-01

    The purpose is to establish the rather complete equations of motion, boundary conditions and equation of energy rate of incremental rate type for micropolar continua. To this end the rather complete definitions for rates of deformation gradient and its inverse are made. The new relations between various stress and couple stress rate tensors are derived.Finally, the coupled equations of motion, boundary conditions and equation of energy rate of incremental rate type for continuum mechanics are obtained as a special case.

  11. Cyclic uniaxial and biaxial hardening of type 304 stainless steel modeled by the viscoplasticity theory based on overstress

    Yao, David; Krempl, Erhard

    1988-01-01

    The isotropic theory of viscoplasticity based on overstress does not use a yield surface or a loading and unloading criterion. The inelastic strain rate depends on overstress, the difference between the stress and the equilibrium stress, and is assumed to be rate dependent. Special attention is paid to the modeling of elastic regions. For the modeling of cyclic hardening, such as observed in annealed Type 304 stainless steel, and additional growth law for a scalar quantity which represents the rate independent asymptotic value of the equilibrium stress is added. It is made to increase with inelastic deformation using a new scalar measure which differentiates between nonproportional and proportional loading. The theory is applied to correlate uniaxial data under two step amplitude loading including the effect of further hardening at the high amplitude and proportional and nonproportional cyclic loadings. Results are compared with corresponding experiments.

  12. Quantification and Three-Dimensional Imaging of the Insulitis-Induced Destruction of β-Cells in Murine Type 1 Diabetes

    Alanentalo, Tomas; Hörnblad, Andreas; Mayans, Sofia; Karin Nilsson, Anna; Sharpe, James; Larefalk, Åsa; Ahlgren, Ulf; Holmberg, Dan

    2010-01-01

    OBJECTIVE The aim of this study was to refine the information regarding the quantitative and spatial dynamics of infiltrating lymphocytes and remaining β-cell volume during the progression of type 1 diabetes in the nonobese diabetic (NOD) mouse model of the disease. RESEARCH DESIGN AND METHODS Using an ex vivo technique, optical projection tomography (OPT), we quantified and assessed the three-dimensional spatial development and progression of insulitis and β-cell destruction in pancreata fro...

  13. Communication: Two types of flat-planes conditions in density functional theory

    Yang, Xiaotian Derrick; Patel, Anand H. G.; Miranda-Quintana, Ramón Alain; Heidar-Zadeh, Farnaz; González-Espinoza, Cristina E.; Ayers, Paul W.

    2016-07-01

    Using results from atomic spectroscopy, we show that there are two types of flat-planes conditions. The first type of flat-planes condition occurs when the energy as a function of the number of electrons of each spin, Nα and Nβ, has a derivative discontinuity on a line segment where the number of electrons, Nα + Nβ, is an integer. The second type of flat-planes condition occurs when the energy has a derivative discontinuity on a line segment where the spin polarization, Nα - Nβ, is an integer, but does not have a discontinuity associated with an integer number of electrons. Type 2 flat planes are rare—we observed just 15 type 2 flat-planes conditions out of the 4884 cases we tested—but their mere existence has implications for the design of exchange-correlation energy density functionals. To facilitate the development of functionals that have the correct behavior with respect to both fractional number of electrons and fractional spin polarization, we present a dataset for the chromium atom and its ions that can be used to test new functionals.

  14. Massless particles, orthosymplectic symmetry and another type of Kaluza-Klein theory

    The superalgebra osp(8/1) is intimately related to the twistor program. Its most singular representation has the following property: restricted to the conformal subalgebra it contains each and every massless representation exactly once. In other words, one irreducible representation of osp(8/1) describes all massless particles with maximal efficiency. It is believed that such unification is required if massless fields of high spins are to have self-consistent interactions. There are other reasons for studying massless particles of all spins simultaneously. There is a very appealing model in which massless particles are viewed as states of two so(3,2) singletons. The astounding fact is that all free two-singleton states are precisely massless. The most singular representation of osp(8/2) is irreducible on osp(8/1) and completely determined by the latter representation. It finds direct application in supergravity theories. The most interesting Sp(8/R) homogeneous space is 10-dimensional. The action of the conformal subgroup leaves invariant a unique 4-dimensional submanifold that can be identified with space time. Kaluza-Klein expansion of the scalar field on 10-space, around this 4-dimensional manifold, leads to a field theory of massless particles with all integer spins on space time. A supersymmetric extension is also possible. (Auth.)

  15. The use of quantitative PCR for identification and quantification of Brachyspira pilosicoli, Lawsonia intracellularis and Escherichia coli fimbrial types F4 and F18 in pig feces.

    Ståhl, M.; Kokotovic, B; Hjulsager, C.K.; Breum, S.Ø.; Angen, Ø.

    2011-01-01

    Abstract Four quantitative PCR (qPCR) assays were evaluated for quantitative detection of Brachyspira pilosicoli, Lawsonia intracellularis, and E. coli fimbrial types F4 and F18 in pig feces. Standard curves were based on feces spiked with the respective reference strains. The detection limits from the spiking experiments were 102 bacteria/g feces for Bpilo-qPCR and Laws-qPCR, 103 CFU/g feces for F4-qPCR and F18-qPCR. The PCR efficiency for all four qPCR assays was between 0.91 and...

  16. A Gaussian-type quadrature formula and its applications to boundary and interface problems in neutron transport theory

    A Gaussian-type quadrature formula is derived for Lebesgue-Stieltjes integrals pertaining to the neutron transport theory (one-velocity, isotropic scattering, plane geometry). The quadrature formula originates from an orthogonality property satisfied by the well-known gsub(n)(c, ν) functions which appear in the solution by Legendre expansion of the transport equation. The quadrature formula thus obtained reduces to the classical Gaussian one in the case of a purely capturing medium. An application to the Milne problem is given. Examples of numerical quadratures are carried out in the appendix

  17. Bianchi type-I massive string magnetized barotropic perfect fluid cosmological model in bimetric theory

    S D Katore; R S Rane; K S Wankhade

    2011-04-01

    Bianchi type-I massive string cosmological model for perfect fluid distribution in the presence of magnetic field is investigated in Rosen’s [Gen. Relativ. Gravit. 4, 435 (1973)] bimetric theory of gravitation. To obtain the deterministic model in terms of cosmic time, we have used the condition $A = (B C)^n$, where n is a constant, between the metric potentials. The magnetic field is due to the electric current produced along the -axis with infinite electrical conductivity. Some physical and geometrical properties of the exhibited model are discussed and studied.

  18. Calculation of Fayet–Iliopoulos D-term in type I string theory revisited: T6/Z3 orbifold case

    The string one-loop computation of the Fayet–Iliopoulos D-term in type I string theory in the case of T6/Z3 orbifold compactification associated with annulus (planar) and the Möbius strip string worldsheet diagrams is reexamined. The mass extracted from the sum of these amplitudes through a limiting procedure is found to be non-vanishing, which is contrary to the earlier computation. The sum can be made finite by a rescaling of the modular parameter in the closed string channel

  19. Five Dimensional Bianchi Type-V Space-Time in f (R,T Theory of Gravityw

    L.S. Ladke,

    2016-02-01

    Full Text Available We study the spatially homogeneous anisotropic Bianchi type-V universe in f(R,T theory of gravity, where R is the Ricci scalar and T is the trace of the energy-momentum tensor. We assume the variation law of mean Hubble parameter and constant deceleration parameter to find two different five dimensional exact solutions of the modified field equations. The first solution yields a singular model for n  0 while the second gives a nonsingular model for n  0. The physical quantities are discussed for both models in future evolution of the universe.

  20. Types of two-dimensional = 4 superconformal field theories

    Abbas Ali

    2003-12-01

    Various types of = 4 superconformal symmetries in two dimensions are considered. It is proposed that apart from the well-known cases of (2) and (2)× (2)× (1), their Kac–Moody symmetry can also be (2)× ((1))4. Operator product expansions for the last case are derived. A complete free field realization for the same is obtained.

  1. Theory of Generalized Bernoulli-Hurwitz Numbers in the Algebraic Functions of Cyclotomic Type

    Ônishi, Yoshihiro

    2003-01-01

    In this paper we announce some results obtained for certain algebraic functions, which we call of cyclotomic type. The main results properly resemble von Staudt-Clausen's theorem and Kummer's congruence for the Bernoulli numbers, and such theorems for the Hurwitz numbers.

  2. Theory of vesicles and droplet type microemulsions : Configurational entropy, size distribution, and measurable properties

    Kegel, W.K.; Reiss, H.

    1996-01-01

    A model of vesicles and droplet type microemulsions is presented. It is shown that the size distribution of the droplets (either vesicles or microemulsions) coexisting with excess fluid is determined in general by only two terms : the free energy of the interface between the drops and the continuous

  3. Theory of light-matter interactions in cascade and diamond type atomic ensembles

    Jen, Hsiang-Hua

    2011-01-01

    In this thesis, we investigate the quantum mechanical interaction of light with matter in the form of a gas of ultracold atoms: the atomic ensemble. We present a theoretical analysis of two problems, which involve the interaction of quantized electromagnetic fields (called signal and idler) with the atomic ensemble (i) cascade two-photon emission in an atomic ladder configuration, and (ii) photon frequency conversion in an atomic diamond configuration. The motivation of these studies comes from potential applications in long-distance quantum communication where it is desirable to generate quantum correlations between telecommunication wavelength light fields and ground level atomic coherences. We develop a theory of correlated signal-idler pair correlation. The analysis is complicated by the possible generation of multiple excitations in the atomic ensemble. An analytical treatment is given in the limit of a single excitation assuming adiabatic laser excitations. The analysis predicts superradiant timescales ...

  4. A New Survey of types of Uncertainties in Nonlinear System with Fuzzy Theory

    Fereshteh Mohammadi

    2013-03-01

    Full Text Available This paper is an attempt to introduce a new framework to handle both uncertainty and time in spatial domain. The application of the fuzzy temporal constraint network (FTCN method is proposed for representation and reasoning of uncertain temporal data. A brief introduction of the fuzzy sets theory is followed by description of the FTCN method with its main algorithms. The paper then discusses the issues of incorporating fuzzy approach into current spatio-temporal processing framework. The general temporal data model is extended to accommodate uncertainties with temporal data and relationships among events. A theoretical FTCN process of fuzzy transition for the imprecise information is introduced with an example. A summary of the paper is given together with outlining some contributions of the paper and future research directions.

  5. Existence of solutions to nonlocal Kirchhoff equations of elliptic type via genus theory

    Nemat Nyamoradi

    2014-04-01

    Full Text Available In this article, we study the existence and multiplicity of solutions to the nonlocal Kirchhoff fractional equation $$\\displaylines{ \\Big(a + b\\int_{\\mathbb{R}^{2N}} |u (x - u (y|^2 K (x - y\\,dx\\,dy\\Big (- \\Delta^s u - \\lambda u = f (x, u (x \\quad \\text{in } \\Omega,\\cr u = 0 \\quad \\text{in } \\mathbb{R}^N \\setminus \\Omega, }$$ where $a, b > 0$ are constants, $(- \\Delta^s$ is the fractional Laplace operator, $s \\in (0, 1$ is a fixed real number, $\\lambda$ is a real parameter and $\\Omega$ is an open bounded subset of $\\mathbb{R}^N$, $N > 2 s$, with Lipschitz boundary, $f: \\Omega \\times \\mathbb{R} \\to \\mathbb{R}$ is a continuous function. The proofs rely essentially on the genus properties in critical point theory.

  6. The use of quantitative PCR for identification and quantification of Brachyspira pilosicoli, Lawsonia intracellularis and Escherichia coli fimbrial types F4 and F18 in pig feces

    Ståhl, Marie; Kokotovic, Branko; Hjulsager, Charlotte Kristiane; Breum, Solvej Østergaard; Angen, Øystein

    than the earlier used method due to improvements in DNA extraction. In addition, as samples were not analysed for all four pathogen agents by traditional diagnostic methods, many samples were found positive for agents that were not expected on the basis of age and case history. The use of quantitative...... using specific standard curves, where each pathogen is analysed in the same matrix as sample DNA. The qPCRs were compared to traditional bacteriological diagnostic methods and found to be more sensitive than cultivation for E. coli and B. pilosicoli. The qPCR assay for Lawsonia was also more sensitive......Four quantitative PCR (qPCR) assays were evaluated for quantitative detection of Brachyspira pilosicoli, Lawsonia intracellularis, and E. coli fimbrial types F4 and F18 in pig feces. Standard curves were based on feces spiked with the respective reference strains. The detection limits from the...

  7. AdS3 xw (S3 x S3 x S1) solutions of type IIB string theory

    We analyse a recently constructed class of local solutions of type IIB supergravity that consist of a warped product of AdS3 with a sevendimensional internal space. In one duality frame the only other nonvanishing fields are the NS three-form and the dilaton. We analyse in detail how these local solutions can be extended to globally well-defined solutions of type IIB string theory, with the internal space having topology S3 x S3 x S1 and with properly quantised three-form flux. We show that many of the dual (0,2) SCFTs are exactly marginal deformations of the (0,2) SCFTs whose holographic duals are warped products of AdS3 with seven-dimensional manifolds of topology S3 x S2 x T2. (orig.)

  8. A cluster randomised pragmatic trial applying Self-determination theory to type 2 diabetes care in general practice

    Juul, Lise; Maindal, Helle T; Zoffmann, Vibeke;

    2011-01-01

    BACKGROUND: Treatment recommendations for prevention of type 2 diabetes complications often require radical and life-long health behaviour changes. Observational studies based on Self-determination theory (SDT) propose substantial factors for the maintenance of behaviour changes and concomitant......, and well-being among a diabetes population, 2) the actual intervention to a level of detail that allows its replication, and 3) the connection between SDT recommendations for health care-provider behaviour and the content of the training course. METHODS/DESIGN: The study is a cluster...... intervention will be assessed on the diabetes populations with regard to well-being (PAID, SF-12), HbA1c- and cholesterol-levels, perceived autonomy support (HCCQ), type of motivation (TSRQ), and perceived competence for diabetes care (PCD) 15-21 months after the core course; the completion of the second...

  9. Wave Concept in the Theory of Hydrodynamical Dispersion - a Maxwellian Type Approach

    Westerterp, K.R.; Kronberg, A.E.; Benneker, A.H.; Dil'man, V.V.

    1996-01-01

    A new approach to the modelling of chemical reactors and contactors is discussed. This approach argues that the dispersion should, under most circumstances, be based on Maxwell's, rather than Fick's diffusion law. As a pair of first-order partial differential equations of the hyperbolic type and requiring only inlet conditions, the wave model is more realistic physically, has a much wider range of validity and in many practical cases is simpler mathematically. Only mass transfer problems are ...

  10. Generic Investigations on Transport Theory Modelling of High Temperature Reactors of Pebble Bed Type

    Sureda Sureda, Antonio Jaime

    2008-01-01

    The GRS (Gesellschaft fuer Anlagen und Reaktorsicherheit = Company for Plant and Reactor Safety) maintains and further develops the code system DORT-TD/HERMIX-DIREKT, which is a complex tool for the simulation of coupled neutronics/thermal-hydraulics transients and accident scenarios of high-temperature gas cooled reactors of pebble bed type. With this tool, GRS takes part in the international benchmark activity "OECD/NEA PBMR400 Transient Benchmark”, which aims at the simulation of transient...

  11. A Global View on The Search for de-Sitter Vacua in (type IIA) String Theory

    Chen, Xingang; Shiu, Gary; Sumitomo, Yoske; Tye, S.-H. Henry

    2011-01-01

    The search for classically stable Type IIA de-Sitter vacua typically starts with an ansatz that gives Anti-de-Sitter supersymmetric vacua and then raises the cosmological constant by modifying the compactification. As one raises the cosmological constant, the couplings typically destabilize the classically stable vacuum, so the probability that this approach will lead to a classically stable de-Sitter vacuum is Gaussianly suppressed. This suggests that classically stable de-Sitter vacua in st...

  12. Uncertainty quantification of effective nuclear interactions

    Perez, R Navarro; Arriola, E Ruiz

    2016-01-01

    We give a brief review on the development of phenomenological NN interactions and the corresponding quantification of statistical uncertainties. We look into the uncertainty of effective interactions broadly used in mean field calculations through the Skyrme parameters and effective field theory counter-terms by estimating both statistical and systematic uncertainties stemming from the NN interaction. We also comment on the role played by different fitting strategies on the light of recent developments.

  13. Recent progress on Kubas-type hydrogen-storage nanomaterials: from theories to experiments

    Chung, ChiHye; Ihm, Jisoon; Lee, Hoonkyung

    2015-06-01

    Transition-metal (TM) atoms are known to form TM-H2 complexes, which are collectively called Kubas dihydrogen complexes. The TM-H2 complexes are formed through the hybridization of the TM d orbitals with the H2 σ and σ* orbitals. The adsorption energy of H2 molecules in the TM-H2 complexes is usually within the range of energy required for reversible H2 storage at room temperature and ambient pressure (-0.4 ~ -0.2 eV/H2). Thus, TM-H2 complexes have been investigated as potential Kubas-type hydrogen-storage materials. Recently, TM-decorated nanomaterials have attracted much attention because of their promising high capacity and reversibility as Kubas-type hydrogen-storage materials. The hydrogen storage capacity of TM-decorated nanomaterials is expected to be as large as ~9 wt%, which is suitable for certain vehicular applications. However, in the TM-decorated nanostructures, the TM atoms prefer to form clusters because of the large cohesive energy (approximately 4 eV), which leads to a significant reduction in the hydrogen-storage capacity. On the other hand, Ca atoms can form complexes with H2 molecules via Kubas-like interactions. Ca atoms attached to nanomaterials have been reported to be able to adsorb as many H2 molecules as TM atoms. Ca atoms tend to cluster less because of the small cohesive energy of bulk Ca (1.83 eV), which is much smaller than those of bulk TMs. These observations suggest thatKubas interactions can occur in d orbital-free elements, thereby making Ca a more suitable element for attracting H2 in hydrogen-storage materials. Recently, Kubas-type TM-based, hydrogen- stor ge materials were experimentally synthesized, and the Kubas-type interactions were measured to be stronger than the van der Waals interactions. In this review, the recent progress of Kubas-type hydrogen- storage materials will be discussed from both theoretical and experimental viewpoints.

  14. Introduction to uncertainty quantification

    Sullivan, T J

    2015-01-01

    Uncertainty quantification is a topic of increasing practical importance at the intersection of applied mathematics, statistics, computation, and numerous application areas in science and engineering. This text provides a framework in which the main objectives of the field of uncertainty quantification are defined, and an overview of the range of mathematical methods by which they can be achieved. Complete with exercises throughout, the book will equip readers with both theoretical understanding and practical experience of the key mathematical and algorithmic tools underlying the treatment of uncertainty in modern applied mathematics. Students and readers alike are encouraged to apply the mathematical methods discussed in this book to their own favourite problems to understand their strengths and weaknesses, also making the text suitable as a self-study. This text is designed as an introduction to uncertainty quantification for senior undergraduate and graduate students with a mathematical or statistical back...

  15. On Ruedenberg's integral approximations and their unrestricted and combined use in molecular orbital theories of Hartree-Fock type

    Ruedenberg's well-known letter of 1951 contains two implications which still have been employed so far in numerical computations: (1) Whenever all types of attraction and repulsion integrals are subject to the Ruedenberg approximations in its simplest form partially known already from Mulliken, the attractive, the Coulomb, as well as the exchange part of the restricted Hartree-Fock-Roothaan equation can be led back to the calculation of corresponding diagonal elements, only. Using Ruedenberg's more elaborate concepts, which are invariant with respect to the rotation of local coordinate axes, the complete Fock-matrix representation can be constructed equivalently from only its own diagonal blocks, each belonging to one atom. Similar formulas are valid for the unrestricted Hartree-Fock theory of Pople and Nesbet. (2) If, however, one prefers to calculate all types of one- and two-center integrals exactly as suggested in Ruedenberg's headline, the original simplicity of both representations is lost. Instead, one is led to more complicated expressions, which arise from the fact that Ruedenberg's integral formulas, when applied to certain kinds of three-center repulsion integrals, imply considerable oversimplifications. In spite of this critical result, Ruedenberg's ideas offer an extension together with an interpretation of the semiempirical Wolfsberg and Helmholz recipe (better known from Hoffmann's extended Hueckel theory), on the one hand, and of the neglect of differential overlap schemes ZDO and NDDO, on the other, from a common point of view

  16. Indirect enzyme-antibody sandwich enzyme-linked immunosorbent assay for quantification of TAXI and XIP type xylanase inhibitors in wheat and other cereals.

    Beaugrand, Johnny; Gebruers, Kurt; Ververken, Cedric; Fierens, Ellen; Dornez, Emmie; Goddeeris, Bruno M; Delcour, Jan A; Courtin, Christophe M

    2007-09-19

    To quantify Triticum aestivum xylanase inhibitor (TAXI) and xylanase inhibiting protein (XIP) type proteins in cereals in general and wheat ( T. aestivum) in particular, a robust enzyme-linked immunosorbent assay (ELISA) using an uncommon enzyme-antibody sandwich format was developed. Bacillus subtilis glycoside hydrolase family (GH) 11 and Aspergillus oryzae GH 10 xylanases were selected for coating ELISA plate wells to capture TAXI and XIP, respectively, prior to probing with antibodies. The detection threshold of the developed ELISA was much lower than that of the currently used xylanase inhibitor assay and the recently described Western blot approach. Because of its broad dynamic range (TAXI, 30-600 ng/mL, and XIP, 3-60 ng/mL), one proper standard extract dilution can be used for analyzing different wheat varieties, whereas for the currently used colorimetric assay, often different dilutions need to be analyzed. The TAXI ELISA for wheat was successfully adapted for barley ( Hordeum vulgare) and could also be used for other cereals. PMID:17715986

  17. Identification and quantification of the caproic acid-producing bacterium Clostridium kluyveri in the fermentation of pit mud used for Chinese strong-aroma type liquor production.

    Hu, Xiao-long; Du, Hai; Xu, Yan

    2015-12-01

    Chinese strong-aroma type liquor (CSAL) is a popular distilled alcoholic beverage in China. It is produced by a complex fermentation process that is conducted in pits in the ground. Ethyl caproate is a key flavor compound in CSAL and is thought to originate from caproic acid produced by Clostridia inhabiting the fermentation pit mud. However, the particular species of Clostridium associated with this production are poorly understood and problematic to quantify by culturing. In this study, a total of 28 closest relatives including 15 Clostridia and 8 Bacilli species in pit muds from three CSAL distilleries, were detected by culture-dependent and -independent methods. Among them, Clostridium kluyveri was identified as the main producer of caproic acid. One representative strain C. kluyveri N6 could produce caproic, butyric and octanoic acids and their corresponding ethyl esters, contributing significantly to CSAL flavor. A real time quantitative PCR assay of C. kluyveri in pit muds developed showed that a concentration of 1.79×10(7) 16S rRNA gene copies/g pit mud in LZ-old pit was approximately six times higher than that in HLM and YH pits and sixty times higher than that in LZ-new pit respectively. This method can be used to improve the management of pit mud microbiology and its impact on CSAL quality. PMID:26267890

  18. Integrating theory and data to create an online self-management programme for adults with type 2 diabetes: HeLP-Diabetes

    Kingshuk Pal

    2015-10-01

    This protocol demonstrates a multi-disciplinary approach to combining evidence from multiple sources to create ’HeLP-Diabetes’: a theory and evidence based online self-management intervention for adults with type 2 diabetes.

  19. Six-Dimensional Superconformal Theories and their Compactifications from Type IIA Supergravity

    Apruzzi, Fabio; Fazzi, Marco; Passias, Achilleas; Rota, Andrea; Tomasiello, Alessandro

    2015-08-01

    We describe three analytic classes of infinitely many AdSd supersymmetric solutions of massive IIA supergravity, for d =7 ,5 ,4 . The three classes are related by simple universal maps. For example, the AdS7×M3 solutions (where M3 is topologically S3 ) are mapped to AdS5×Σ2×M3' , where Σ2 is a Riemann surface of genus g ≥2 and the metric on M3' is obtained by distorting M3 in a certain way. The solutions can have localized D6 or O6 sources, as well as an arbitrary number of D8-branes. The AdS7 case (previously known only numerically) is conjecturally dual to an NS5-D6-D8 system. The field theories in three and four dimensions are not known, but their number of degrees of freedom can be computed in the supergravity approximation. The AdS4 solutions have numerical "attractor" generalizations that might be useful for flux compactification purposes.

  20. Supersymmetric Intersecting D6-Branes and Fluxes in Massive Type IIA String Theory

    Behrndt, K.; Cvetic, M.

    2004-01-01

    We study N=1 supersymmetric four-dimensional solutions of massive Type IIA supergravity with intersecting D6-branes in the presence NS-NS three-form fluxes. We derive N=1 supersymmetry conditions for the D6-brane and flux configurations in an internal manifold $X_6$ and derive the intrinsic torsion (or SU(3)-structure) related to the fluxes. In the absence of fluxes, N=1 supersymmetry implies that D6-branes wrap supersymmetric three-cycles of $X_6$ that intersect at angles of SU(3) rotations ...

  1. To the theory of $q$-ary Steiner and other-type trades

    Krotov, Denis; Mogilnykh, Ivan; Potapov, Vladimir

    2014-01-01

    We introduce the concept of a clique bitrade, which generalizes several known types of bitrades, including latin bitrades, Steiner $T(k-1,k,v)$ bitrades, extended $1$-perfect bitrades. For a distance-regular graph, we show a one-to-one correspondence between the clique bitrades that meet the weight-distribution lower bound on the cardinality and the bipartite isometric subgraphs that are distance-regular with certain parameters. As an application of the results, we find the minimum cardinalit...

  2. Le rapport paradoxal de l'économie scientifique à la quantification des phénomènes économiques le cas de la "positive accounting theory"

    Chiapello, Eve; Desrosières, A.

    2004-01-01

    International audience Nous traitons dans cet article de la quantification économique Et de son utilisation par la recherche en économie, en embrassant ses différentes sources qu'elles soient comptables ou statistiques. Diverses interrogations nous ont guidés. La première est la méconnaissance qu'ont souvent les économistes des opérations de quantification de l'économie notamment comptables qui leur sont pourtant utiles dans leurs travaux empiriques. La seconde est l'accroissement historiq...

  3. TH-C-19A-09: Quantification of Transmission and Backscatter Factors as a function of Distance to Inhomogeneity Interface for Three Types of Surgical Implant Plates

    Purpose: Carbon fiber materials have been increasingly used clinically, mainly in orthopedics, as an alternative to metallic implants because of their minimal artifacts on CT and MRI images. This study characterizes the transmission and backscatter property of carbon fiber plates (CarboFix Orthopedics, Herzeliya, Israel) with measurements for radiation therapy applications, and compares them to traditional Stainless Steel (SS) and Titanium (Ti) metal materials. Methods: For the transmission measurements, 1-mm-thick test plate was placed upstream from a plane parallel Markus chamber, separated by various thicknesses of polystyrene plates in 0.5 cm increments between 0 and 5 cm. With this setup, we quantified the radiation transmission as a function of distance to the inhomogeneity interface. The LINAC source to detector distance was maintained at 100 cm and 200 MU was delivered for each measurement. Two 3-cm solid water phantoms were placed at the top and bottom to provide build up. All the measurements were performed for 6 MV and 18 MV photons. The backscatter measurements had the identical setup, except that the test plate was downstream of the chamber from radiation. Results: The carbon fiber plates did not introduce any measureable inhomogeneity effect on the transmission and backscatter factor because of its low atomic number. In contrast, traditional metal implant materials caused up to 15% dose difference at upstream and 25% backscatter at downstream from radiation. Such differences decrease as the distance to the inhomogeneity interface increases and become unmeasurable at distance of 3 cm and 1 cm for upstream and downstream, respectively. Conclusion: A new type of carbon fiber implant plate was evaluated and found to have minimal inhomogeneity effect in MV radiation beams. Patients would benefit from a carbon based implant over metal for radiation therapy due to their minimal backscatter and imaging artifacts

  4. TH-C-19A-09: Quantification of Transmission and Backscatter Factors as a function of Distance to Inhomogeneity Interface for Three Types of Surgical Implant Plates

    Wilson, D; Mills, M; Wang, B [University of Louisville, Louisville, KY (United States)

    2014-06-15

    Purpose: Carbon fiber materials have been increasingly used clinically, mainly in orthopedics, as an alternative to metallic implants because of their minimal artifacts on CT and MRI images. This study characterizes the transmission and backscatter property of carbon fiber plates (CarboFix Orthopedics, Herzeliya, Israel) with measurements for radiation therapy applications, and compares them to traditional Stainless Steel (SS) and Titanium (Ti) metal materials. Methods: For the transmission measurements, 1-mm-thick test plate was placed upstream from a plane parallel Markus chamber, separated by various thicknesses of polystyrene plates in 0.5 cm increments between 0 and 5 cm. With this setup, we quantified the radiation transmission as a function of distance to the inhomogeneity interface. The LINAC source to detector distance was maintained at 100 cm and 200 MU was delivered for each measurement. Two 3-cm solid water phantoms were placed at the top and bottom to provide build up. All the measurements were performed for 6 MV and 18 MV photons. The backscatter measurements had the identical setup, except that the test plate was downstream of the chamber from radiation. Results: The carbon fiber plates did not introduce any measureable inhomogeneity effect on the transmission and backscatter factor because of its low atomic number. In contrast, traditional metal implant materials caused up to 15% dose difference at upstream and 25% backscatter at downstream from radiation. Such differences decrease as the distance to the inhomogeneity interface increases and become unmeasurable at distance of 3 cm and 1 cm for upstream and downstream, respectively. Conclusion: A new type of carbon fiber implant plate was evaluated and found to have minimal inhomogeneity effect in MV radiation beams. Patients would benefit from a carbon based implant over metal for radiation therapy due to their minimal backscatter and imaging artifacts.

  5. [Genetic and humoral autoimmunity markers of type 1 diabetes: from theory to practice].

    Silva, Maria Elizabeth Rossi da; Mory, Denise; Davini, Elaine

    2008-03-01

    Type 1 A diabetes mellitus (T1AD) results from the autoimmune destruction of the insulin producing pancreatic beta-cells. The largest contribution to genetic susceptibility comes from several genes located in the major histocompatibility complex on chromosome 6p21.3 (IDDM1 locus), accounting for at least 40% of the family aggregation of this disease. The highest-risk human leukocyte antigen HLA genotype for T1AD is DR3-DQA1*0501-DQB1*0201/DR4-DQA1*0301-DQB1*0302, whereas -DR15-DQA1*0102-DQB1*0602 haplotype is associated with dominant protection. Three other T1D loci associated with predisposition are the Variable Number for Tandem Repeats (VNTR) near the insulin gene (IDDM2), which accounts to 10% of genetic susceptibility, the Cytotoxic T-Lymphocyte-associated Antigen (CTLA-4)(IDDM 12) and the Protein Tyrosine Phosphatasis Nonreceptor-type 22 (PTPN22). Many other gene suspected to predispose to autoimmunity have been investigated. T1AD is frequently associated with autoimmune thyroid disease, celiac disase, Addison s disease and many other autoimmune diseases, characterized by organ-specific autoantibodies and related to the same genetic background. Using these autoantibodies, organ specific autoimmunity may be detected before the development of clinical disease preventing significant morbidity. PMID:18438527

  6. Mushroom-type structures with the wires connected through diodes: Theory and applications

    Forouzmand, Ali; Kaipa, Chandra S. R.; Yakovlev, Alexander B.

    2016-07-01

    In this paper, we establish a general formalism to quantify the interaction of electromagnetic waves with mushroom-type structures (high impedance surface and bi-layer) with diodes inserted along the direction of the wires. The analysis is carried out using the nonlocal homogenization model for the mushroom structure with the generalized additional boundary conditions at the connection of the wires to diodes. We calculate numerically the magnitude and phase of the reflected/transmitted fields in the presence of an ideal and realistic PIN diodes. It is observed that the reflection/transmission characteristics of the mushroom-type structures can be controlled by tuning the working states of the integrated PIN diodes. We realize a structure with a multi-diode switch to minimize the undesired transmission for a particular incident angle. In addition, a dual-band subwavelength imaging lens is designed based on the resonant amplification of evanescent waves, wherein the operating frequency can be tuned by changing the states of the PIN diodes. The analytical results are verified with the full-wave electromagnetic solver CST Microwave Studio, showing a good agreement.

  7. On the use of K\\"ulshammer type invariants in representation theory

    Zimmermann, Alexander

    2010-01-01

    Since 2005 a new powerful invariant of an algebra emerged using earlier work of Horv\\'ath, H\\'ethelyi, K\\"ulshammer and Murray. The authors studied Morita invariance of a sequence of ideals of the centre of a finite dimensional algebra over a field of finite characteristic. It was shown that the sequence of ideals is actually a derived invariant, and most recently a slightly modified version of it an invariant under stable equivalences of Morita type. The invariant was used in various contexts to distinguish derived and stable equivalence classes of pairs of algebras in very subtle situations. Generalisations to non symmetric algebras and to higher Hochschild (co-)homology was given. This article surveys the results and gives some of the constructions in more detail.

  8. Disease quantification in dermatology

    Greve, Tanja Maria; Kamp, Søren; Jemec, Gregor B E

    2013-01-01

    Accurate documentation of disease severity is a prerequisite for clinical research and the practice of evidence-based medicine. The quantification of skin diseases such as psoriasis currently relies heavily on clinical scores. Although these clinical scoring methods are well established and very ...

  9. Type Ia Supernovae and their Environment: Theory and Applications to SN 2014J

    Dragulin, Paul

    2015-01-01

    We present theoretical semi-analytic models for the interaction of stellar winds with the interstellar medium (ISM) or prior mass loss implemented in our code SPICE (Supernovae Progenitor Interaction Calculator for parameterized Environments, available on request), assuming spherical symmetry and power-law ambient density profiles and using the Pi-theorem. This allows us to test a wide variety of configurations, their functional dependencies, and to find classes of solutions for given observations. Here, we study Type Ia (SN~Ia) surroundings of single and double degenerate systems, and their observational signatures. Winds may originate from the progenitor prior to the white dwarf (WD) stage, the WD, a donor star, or an accretion disk (AD). For M_Ch explosions,the AD wind dominates and produces a low-density void several light years across surrounded by a dense shell. The bubble explains the lack of observed interaction in late time SN light curves for, at least, several years. The shell produces narrow ISM l...

  10. Development of flow network analysis code for block type VHTR core by linear theory method

    VHTR (Very High Temperature Reactor) is high-efficiency nuclear reactor which is capable of generating hydrogen with high temperature of coolant. PMR (Prismatic Modular Reactor) type reactor consists of hexagonal prismatic fuel blocks and reflector blocks. The flow paths in the prismatic VHTR core consist of coolant holes, bypass gaps and cross gaps. Complicated flow paths are formed in the core since the coolant holes and bypass gap are connected by the cross gap. Distributed coolant was mixed in the core through the cross gap so that the flow characteristics could not be modeled as a simple parallel pipe system. It requires lot of effort and takes very long time to analyze the core flow with CFD analysis. Hence, it is important to develop the code for VHTR core flow which can predict the core flow distribution fast and accurate. In this study, steady state flow network analysis code is developed using flow network algorithm. Developed flow network analysis code was named as FLASH code and it was validated with the experimental data and CFD simulation results. (authors)

  11. Quantification of Cannabinoid Content in Cannabis

    Tian, Y.; Zhang, F.; Jia, K.; Wen, M.; Yuan, Ch.

    2015-09-01

    Cannabis is an economically important plant that is used in many fields, in addition to being the most commonly consumed illicit drug worldwide. Monitoring the spatial distribution of cannabis cultivation and judging whether it is drug- or fiber-type cannabis is critical for governments and international communities to understand the scale of the illegal drug trade. The aim of this study was to investigate whether the cannabinoids content in cannabis could be spectrally quantified using a spectrometer and to identify the optimal wavebands for quantifying the cannabinoid content. Spectral reflectance data of dried cannabis leaf samples and the cannabis canopy were measured in the laboratory and in the field, respectively. Correlation analysis and the stepwise multivariate regression method were used to select the optimal wavebands for cannabinoid content quantification based on the laboratory-measured spectral data. The results indicated that the delta-9-tetrahydrocannabinol (THC) content in cannabis leaves could be quantified using laboratory-measured spectral reflectance data and that the 695 nm band is the optimal band for THC content quantification. This study provides prerequisite information for designing spectral equipment to enable immediate quantification of THC content in cannabis and to discriminate drug- from fiber-type cannabis based on THC content quantification in the field.

  12. Type Ia Supernovae and Their Environment:Theory and Applications to SN 2014J

    Dragulin, Paul; Hoeflich, Peter

    2016-02-01

    We present theoretical semi-analytic models for the interaction of stellar winds with the interstellar medium (ISM) or prior mass loss implemented in our code SPICE, assuming spherical symmetry and power-law ambient density profiles and using the Π-theorem. This allows us to test a wide variety of configurations, their functional dependencies, and to find classes of solutions for given observations. Here, we study Type Ia Supernova (SN Ia) surroundings of single and double degenerate systems, and their observational signatures. Winds may originate from the progenitor prior to the white dwarf (WD) stage, the WD, a donor star, or an accretion disk (AD). For MCh explosions, the AD wind dominates and produces a low-density void several light years across, surrounded by a dense shell. The bubble explains the lack of observed interaction in late time SN light curves for, at least, several years. The shell produces narrow ISM lines Doppler shifted by 10-100 km s-1, and equivalent widths of ≈100 mÅ and ≈1 mÅ in cases of ambient environments with constant density and produced by prior mass loss, respectively. For SN2014J, both mergers and MCh mass explosions have been suggested based on radio and narrow lines. As a consistent and most likely solution, we find an AD wind running into an environment produced by the red giant wind of the progenitor during the pre-WD stage, and a short delay, 0.013-1.4 Myr, between the WD formation and the explosion. Our framework may be applied more generally to stellar winds and star formation feedback in large scale galactic evolution simulations.

  13. Band-gap corrected density functional theory calculations for InAs/GaSb type II superlattices

    We performed pseudopotential based density functional theory (DFT) calculations for GaSb/InAs type II superlattices (T2SLs), with bandgap errors from the local density approximation mitigated by applying an empirical method to correct the bulk bandgaps. Specifically, this work (1) compared the calculated bandgaps with experimental data and non-self-consistent atomistic methods; (2) calculated the T2SL band structures with varying structural parameters; (3) investigated the interfacial effects associated with the no-common-atom heterostructure; and (4) studied the strain effect due to lattice mismatch between the two components. This work demonstrates the feasibility of applying the DFT method to more exotic heterostructures and defect problems related to this material system

  14. Monte Carlo simulation of transfer reactions using extended R-matrix theory picturing surrogate-type WFCF features

    Bouland, Olivier H.

    2016-03-01

    This article supplies an overview of issues related to the interpretation of surrogate measurement results for neutron-incident cross section predictions; difficulties that are somehow masked by the historical conversion route based on Weisskopf-Ewing approximation. Our proposal is to handle the various difficulties by using a more rigorous approach relying on Monte Carlo simulation of transfer reactions with extended R-matrix theory. The multiple deficiencies of the historical surrogate treatment are recalled but only one is examined in some details here; meaning the calculation of in-out-going channel Width Fluctuation Correction Factors (WFCF) which behavior witness partly the failure of Niels Bohr's compound nucleus theoretical landmark. Relevant WFCF calculations according to neutron-induced surrogate- and cross section-types as a function of neutron-induced fluctuating energy range [0 - 2.1 MeV] are presented and commented in the case of the 240Pu* and 241Pu* compound nucleus isotopes.

  15. Bianchi Type-I Massive String Magnetized Barotropic Perfect Fluid Cosmological Model in the Bimetric Theory of Gravitation

    N. P. Gaikwad; M. S. Borkar; S. S. Charjan

    2011-01-01

    @@ We investigate the Bianchi type-I massive string magnetized barotropic perfect fluid cosmological model in Rosen's bimetric theory of gravitation with and without a magnetic field by applying the techniques used by Latelier(1979,1980) and Stachel(1983).To obtain a deterministic model of the universe, it is assumed that the universe is filled with barotropic perfect fluid distribution.The physical and geometrical significance of the model are discussed.By comparing our model with the model of Bali et al.(2007), it is realized that there are no big-bang and big-crunch singularities in our model and T=0 is not the time of the big bang, whereas the model of Bali et al.starts with a big bang at T=0.Further, our model is in agreement with Bali et al.(2007) as time increases in the presence, as well as in the absence, of a magnetic field.

  16. Bianchi Type-I Massive String Magnetized Barotropic Perfect Fluid Cosmological Model in the Bimetric Theory of Gravitation

    We investigate the Bianchi type-I massive string magnetized barotropic perfect fluid cosmological model in Rosen's bimetric theory of gravitation with and without a magnetic field by applying the techniques used by Latelier (1979, 1980) and Stachel (1983). To obtain a deterministic model of the universe, it is assumed that the universe is filled with barotropic perfect fluid distribution. The physical and geometrical significance of the model are discussed. By comparing our model with the model of Bali et al. (2007), it is realized that there are no big-bang and big-crunch singularities in our model and T = 0 is not the time of the big bang, whereas the model of Bali et al. starts with a big bang at T = 0. Further, our model is in agreement with Bali et al. (2007) as time increases in the presence, as well as in the absence, of a magnetic field. (geophysics, astronomy, and astrophysics)

  17. Flux-induced Soft Terms on Type IIB/F-theory Matter Curves and Hypercharge Dependent Scalar Masses

    Camara, Pablo G; Valenzuela, Irene

    2014-01-01

    Closed string fluxes induce generically SUSY-breaking soft terms on supersymmetric type IIB orientifold compactifications with D3/D7 branes. This was studied in the past by inserting those fluxes on the DBI+CS actions for adjoint D3/D7 fields, where D7-branes had no magnetic fluxes. In the present work we generalise those computations to the phenomenologically more relevant case of chiral bi-fundamental fields laying at 7-brane intersections and F-theory local matter curves. We also include the effect of 7-brane magnetic flux as well as more general closed string backgrounds, including the effect of distant (anti-)D3-branes. We discuss several applications of our results. We find that squark/slepton masses become in general flux-dependent in F-theory GUT's. Hypercharge-dependent non-universal scalar masses with a characteristic sfermion hierarchy m_E^2 < m_L^2 < m_Q^2 < m_D^2 < m_U^2 are obtained. There are also flavor-violating soft terms both for matter fields living at intersecting 7-branes or ...

  18. Factors Influencing Physical Activity Behavior among Iranian Women with Type 2 Diabetes Using the Extended Theory of Reasoned Action

    Alireza Didarloo

    2011-10-01

    Full Text Available BackgroundFindings of most studies indicate that the only way to control diabetes and prevent its debilitating effects is through the continuous performance of self-care behaviors. Physical activity is a non-pharmacological method of diabetes treatment and because of its positive effects on diabetic patients, it is being increasingly considered by researchers and practitioners. This study aimed at determining factors influencing physical activity among diabetic women in Iran, using the extended theory of reasoned action in Iran.MethodsA sample of 352 women with type 2 diabetes, referring to a Diabetes Clinic in Khoy, Iran, participated in the study. Appropriate instruments were designed to measure the desired variables (knowledge of diabetes, personal beliefs, subjective norms, perceived self-efficacy, behavioral intention and physical activity behavior. The reliability and validity of the instruments were examined and approved. Statistical analyses of the study were conducted by inferential statistical techniques (independent t-test, correlations and regressions using the SPSS package.ResultsThe findings of this investigation indicated that among the constructs of the model, self efficacy was the strongest predictor of intentions among women with type 2 diabetes and both directly and indirectly affected physical activity. In addition to self efficacy, diabetic patients' physical activity also was influenced by other variables of the model and sociodemographic factors.ConclusionOur findings suggest that the high ability of the theory of reasoned action extended by self-efficacy in forecasting and explaining physical activity can be a base for educational intervention. Educational interventions based on the proposed model are necessary for improving diabetics' physical activity behavior and controlling disease.

  19. Morse Index and Linear Stability of the Lagrangian Circular Orbit in a Three-Body-Type Problem Via Index Theory

    Barutello, Vivina; Jadanza, Riccardo D.; Portaluri, Alessandro

    2016-01-01

    It is well known that the linear stability of the Lagrangian elliptic solutions in the classical planar three-body problem depends on a mass parameter β and on the eccentricity e of the orbit. We consider only the circular case ( e = 0) but under the action of a broader family of singular potentials: α-homogeneous potentials, for α in (0, 2), and the logarithmic one. It turns out indeed that the Lagrangian circular orbit persists also in this more general setting. We discover a region of linear stability expressed in terms of the homogeneity parameter α and the mass parameter β, then we compute the Morse index of this orbit and of its iterates and we find that the boundary of the stability region is the envelope of a family of curves on which the Morse indices of the iterates jump. In order to conduct our analysis we rely on a Maslov-type index theory devised and developed by Y. Long, X. Hu and S. Sun; a key role is played by an appropriate index theorem and by some precise computations of suitable Maslov-type indices.

  20. Self-organized criticality as Witten-type topological field theory with spontaneously broken Becchi-Rouet-Stora-Tyutin symmetry

    Here, a scenario is proposed, according to which a generic self-organized critical (SOC) system can be looked upon as a Witten-type topological field theory (W-TFT) with spontaneously broken Becchi-Rouet-Stora-Tyutin (BRST) symmetry. One of the conditions for the SOC is the slow driving noise, which unambiguously suggests Stratonovich interpretation of the corresponding stochastic differential equation (SDE). This, in turn, necessitates the use of Parisi-Sourlas-Wu stochastic quantization procedure, which straightforwardly leads to a model with BRST-exact action, i.e., to a W-TFT. In the parameter space of the SDE, there must exist full-dimensional regions where the BRST symmetry is spontaneously broken by instantons, which in the context of SOC are essentially avalanches. In these regions, the avalanche-type SOC dynamics is liberated from overwise a rightful dynamics-less W-TFT, and a Goldstone mode of Fadeev-Popov ghosts exists. Goldstinos represent moduli of instantons (avalanches) and being gapless are responsible for the critical avalanche distribution in the low-energy, long-wavelength limit. The above arguments are robust against moderate variations of the SDE's parameters and the criticality is 'self-tuned'. The proposition of this paper suggests that the machinery of W-TFTs may find its applications in many different areas of modern science studying various physical realizations of SOC. It also suggests that there may in principle exist a connection between some SOC's and the concept of topological quantum computing.

  1. Motivational Profiles for Physical Activity Practice in Adults with Type 2 Diabetes: A Self-Determination Theory Perspective.

    Gourlan, Mathieu; Trouilloud, David; Boiché, Julie

    2016-01-01

    Drawing on Self-Determination Theory, this study explored the motivational profiles toward Physical Activity (PA) among adults with type 2 diabetes and the relationships between motivational profile, perceived competence and PA. Participants were 350 men and women (Mean age 62.77 years) who were interviewed on their motivations toward PA, perceived level of competence to practice, and PA practice. Cluster analyses reveal the existence of three distinct profiles: "High Combined" (ie, high scores on motivations ranging from intrinsic to external regulation, moderate level on amotivation), "Self-Determined" (ie, high scores on intrinsic, integrated, and identified regulations; low scores on other regulations), and "Moderate" (ie, moderate scores on all regulations). Participants with "High Combined" and "Self-Determined" profiles reported higher perceived competence and longer leisure-time PA practice in comparison to those with a "Moderate" profile. This study highlights the necessity of adopting a person-centered approach to better understand motivation toward PA among type 2 diabetics. PMID:25961448

  2. Quantification of Human T-lymphotropic virus type I (HTLV-I) provirus load in a rural West African population: no enhancement of human immunodeficiency virus type 2 pathogenesis, but HTLV-I provirus load relates to mortality

    Ariyoshi, K; Berry, N; Cham, F;

    2003-01-01

    Human T-lymphotropic virus type I (HTLV-I) provirus load was examined in a cohort of a population in Guinea-Bissau among whom human immunodeficiency virus (HIV) type 2 is endemic. Geometric mean of HIV-2 RNA load among HTLV-I-coinfected subjects was significantly lower than that in subjects...... infected with HIV-2 alone (212 vs. 724 copies/mL; P=.02). Adjusted for age, sex, and HIV status, the risk of death increased with HTLV-I provirus load; mortality hazard ratio was 1.59 for each log10 increase in HTLV-I provirus copies (P=.038). There is no enhancing effect of HTLV-I coinfection on HIV-2...

  3. Effectiveness of training on preventative nutritional behaviors for type-2 diabetes among the female adolescents: Examination of theory of planned behavior

    Maleki, Farzaneh; Hosseini Nodeh, Zahra; Rahnavard, Zahra; Arab, Masoume

    2016-01-01

    Background: Since type-2 diabetes is the most common chronic disease among Iranian female adolescents, we applied theory of planned behavior to examine the effect of training to intention to preventative nutritional behaviors for type-2 diabetes among female adolescents. Methods: In this experimental study 200 (11-14 year old) girls from 8 schools of Tehran city (100 in each intervention and control group) were recruited based on cluster sampling method during two stages. For intervention group, an educational program was designed based on the theory of planned behavior and presented in 6 workshop sessions to prevent type-2 diabetes. The data were collected before and two months after the workshops using a valid and reliable (α=0.72 and r=0.80) authormade questionnaire based on Ajzens TPB questionnaire manual. The data were analyzed using t-test, chi-square test and analysis of covariance. Results: Findings indicate that the two groups were homogeneous regarding the demographic characteristics before education, but the mean score of the theory components (attitudes, subjective norms, perceived behavioral control, and intention) was higher in the control group. Also, results showed all of the theory components significantly increased after the education in the intervention group (p=0.000). Conclusion: Training based on the theory of planned behavior enhances the intention to adherence preventative nutritional behaviors for type-2 diabetes among the studied female adolescents. PMID:27390718

  4. Transparent quantification into hyperintensional contexts

    Duží, M.; Jespersen, Bjorn

    London : College Publications, 2011 - (Peliš, M.; Punčochář, V.), s. 81-97 ISBN 978-1-84890-038-7. [ LOGICA 2010. Hejnice (CZ), 21.06.2010-25.06.2010] Institutional research plan: CEZ:AV0Z90090514 Keywords : hyperintensions * type theory * Transparant intensional logic * propositional attitudes Subject RIV: AA - Philosophy ; Religion

  5. A note on teleparallel Killing vector fields in Bianchi type VIII and IX space—times in teleparallel theory of gravitation

    In this paper we classify Bianchi type VIII and IX space—times according to their teleparallel Killing vector fields in the teleparallel theory of gravitation by using a direct integration technique. It turns out that the dimensions of the teleparallel Killing vector fields are either 4 or 5. From the above study we have shown that the Killing vector fields for Bianchi type VIII and IX space—times in the context of teleparallel theory are different from that in general relativity. (general)

  6. Monte Carlo simulation of transfer reactions using extended R-matrix theory picturing surrogate-type WFCF features

    Bouland Olivier H.

    2016-01-01

    Full Text Available This article supplies an overview of issues related to the interpretation of surrogate measurement results for neutron-incident cross section predictions; difficulties that are somehow masked by the historical conversion route based on Weisskopf-Ewing approximation. Our proposal is to handle the various difficulties by using a more rigorous approach relying on Monte Carlo simulation of transfer reactions with extended R-matrix theory. The multiple deficiencies of the historical surrogate treatment are recalled but only one is examined in some details here; meaning the calculation of in-out-going channel Width Fluctuation Correction Factors (WFCF which behavior witness partly the failure of Niels Bohr’s compound nucleus theoretical landmark. Relevant WFCF calculations according to neutron-induced surrogate- and cross section-types as a function of neutron-induced fluctuating energy range [0 - 2.1 MeV] are presented and commented in the case of the 240Pu* and 241Pu* compound nucleus isotopes.

  7. Selection of Treatment Strategies among Patients with Type 2 Diabetes Mellitus in Malaysia: A Grounded Theory Approach.

    Lee Lan Low

    Full Text Available Diabetes Mellitus is a multifaceted chronic illness and its life-long treatment process requires patients to continuously engage with the healthcare system. The understanding of how patients manoeuvre through the healthcare system for treatment is crucial in assisting them to optimise their disease management. This study aims to explore issues determining patients' treatment strategies and the process of patients manoeuvring through the current healthcare system in selecting their choice of treatment for T2DM.The Grounded Theory methodology was used. Twelve patients with Type 2 Diabetes Mellitus, nine family members and five healthcare providers from the primary care clinics were interviewed using a semi-structured interview guide. Three focus group discussions were conducted among thirteen healthcare providers from public primary care clinics. Both purposive and theoretical samplings were used for data collection. The interviews were audio-taped and transcribed verbatim, followed by line-by-line coding and constant comparison to identify the categories and core category.The concept of "experimentation" was observed in patients' help-seeking behaviour. The "experimentation" process required triggers, followed by information seeking related to treatment characteristics from trusted family members, friends and healthcare providers to enable decisions to be made on the choice of treatment modalities. The whole process was dynamic and iterative through interaction with the healthcare system. The decision-making process in choosing the types of treatment was complex with an element of trial-and-error. The anchor of this process was the desire to fulfil the patient's expected outcome.Patients with Type 2 Diabetes Mellitus continuously used "experimentation" in their treatment strategies and help-seeking process. The "experimentation" process was experiential, with continuous evaluation, information seeking and decision-making tinged with the element

  8. Adjoint-Based Uncertainty Quantification with MCNP

    Seifried, Jeffrey E. [Univ. of California, Berkeley, CA (United States)

    2011-09-01

    This work serves to quantify the instantaneous uncertainties in neutron transport simulations born from nuclear data and statistical counting uncertainties. Perturbation and adjoint theories are used to derive implicit sensitivity expressions. These expressions are transformed into forms that are convenient for construction with MCNP6, creating the ability to perform adjoint-based uncertainty quantification with MCNP6. These new tools are exercised on the depleted-uranium hybrid LIFE blanket, quantifying its sensitivities and uncertainties to important figures of merit. Overall, these uncertainty estimates are small (< 2%). Having quantified the sensitivities and uncertainties, physical understanding of the system is gained and some confidence in the simulation is acquired.

  9. Effectiveness of training on preventative nutritional behaviors for type-2 diabetes among the female adolescents: Examination of theory of planned behavior

    Maleki, Farzaneh; Hosseini Nodeh, Zahra; Rahnavard, Zahra; Arab, Masoume

    2016-01-01

    Background: Since type-2 diabetes is the most common chronic disease among Iranian female adolescents, we applied theory of planned behavior to examine the effect of training to intention to preventative nutritional behaviors for type-2 diabetes among female adolescents. Methods: In this experimental study 200 (11-14 year old) girls from 8 schools of Tehran city (100 in each intervention and control group) were recruited based on cluster sampling method during two stages. For intervention gro...

  10. Prediction of Self-Management Behavior among Iranian Women with Type 2 Diabetes: Application of the Theory of Reasoned Action along with Self-Efficacy (ETRA)

    Didarloo, A R; Shojaeizadeh, D; Gharaaghaji ASL, R; Habibzadeh, H; Niknami, Sh; Pourali, R

    2012-01-01

    Background Continuous performing of diabetes self-care behaviors was shown to be an effective strategy to control diabetes and to prevent or reduce its- related complications. This study aimed to investigate predictors of self-care behavior based on the extended theory of reasoned action by self efficacy (ETRA) among women with type 2 diabetes in Iran. Methods A sample of 352 women with type 2 diabetes, referring to a Diabetes Clinic in Khoy, Iran using the nonprobability sampling was enrolle...

  11. Predicting Noninsulin Antidiabetic Drug Adherence Using a Theoretical Framework Based on the Theory of Planned Behavior in Adults With Type 2 Diabetes

    Zomahoun, Hervé Tchala Vignon; Moisan, Jocelyne; Lauzier, Sophie; Guillaumie,Laurence; Grégoire, Jean-Pierre; Guénette, Line

    2016-01-01

    Abstract Understanding the process behind noninsulin antidiabetic drug (NIAD) nonadherence is necessary for designing effective interventions to resolve this problem. This study aimed to explore the ability of the theory of planned behavior (TPB), which is known as a good predictor of behaviors, to predict the future NIAD adherence in adults with type 2 diabetes. We conducted a prospective study of adults with type 2 diabetes. They completed a questionnaire on TPB variables and external varia...

  12. Effective potential in non-supersymmetric SU(N) x SU(N) gauge theory and interactions of type 0 D3-branes

    Tseytlin, Arkady A

    1999-01-01

    We study some aspects of short-distance interaction between parallel D3-branes in type 0 string theory as described by the corresponding world-volume gauge theory. We compute the one-loop effective potential in the non-supersymmetric SU(N) x SU(N) gauge theory (which is a Z_2 projection of the U(2N) n=4 SYM theory) representing dyonic branes composed of N electric and N magnetic D3-branes. The branes of the same type repel at short distances, but an electric and a magnetic brane attract, and the forces between self-dual branes cancel. The self-dual configuration (with the positions of the electric and the magnetic branes, i.e. the diagonal entries of the adjoint scalar fields, being the same) is stable against separation of one electric or one magnetic brane, but is unstable against certain modes of separation of several same-type branes. This instability should be suppressed in the large N limit, i.e. should be irrelevant for the large N CFT interpretation of the gauge theory suggested in hep-th/9901101.

  13. Using psychological theory to understand the clinical management of type 2 diabetes in Primary Care: a comparison across two European countries.

    Hrisos, S.; Eccles, M.P.; Francis, J.J.; Bosch, M.C.; Dijkstra, R.F.; Johnston, M.; Grol, R.P.T.M.; Kaner, E.F.; Steen, I.N.

    2009-01-01

    BACKGROUND: Long term management of patients with Type 2 diabetes is well established within Primary Care. However, despite extensive efforts to implement high quality care both service provision and patient health outcomes remain sub-optimal. Several recent studies suggest that psychological theori

  14. Session Types = Intersection Types + Union Types

    Padovani, Luca

    2011-01-01

    We propose a semantically grounded theory of session types which relies on intersection and union types. We argue that intersection and union types are natural candidates for modeling branching points in session types and we show that the resulting theory overcomes some important defects of related behavioral theories. In particular, intersections and unions provide a native solution to the problem of computing joins and meets of session types. Also, the subtyping relation turns out to be a pre-congruence, while this is not always the case in related behavioral theories.

  15. Prospects of using the second-order perturbation theory of the MP2 type in the theory of electron scattering by polyatomic molecules

    Čársky, Petr

    2015-01-01

    Roč. 191, č. 2015 (2015), s. 191-192. ISSN 1551-7616 R&D Projects: GA MŠk OC09079; GA MŠk(CZ) OC10046; GA ČR GA202/08/0631 Grant ostatní: COST(XE) CM0805; COST(XE) CM0601 Institutional support: RVO:61388955 Keywords : electron-scattering * calculation of cross sections * second-order perturbation theory Subject RIV: CF - Physical ; Theoretical Chemistry

  16. Students' Personality Types, Intended Majors, and College Expectations: Further Evidence Concerning Psychological and Sociological Interpretations of Holland's Theory

    Pike, Gary R.

    2006-01-01

    Because it focuses on the interactions between students and their environments, Holland's theory of vocational choice provides a powerful framework for studying college experiences. The present study assessed the relative merits of psychological and sociological interpretations of Holland's theory by examining the relationships among students' …

  17. Understanding the p-Type Conduction Properties of the Transparent Conducting Oxide CuBO2: A Density Functional Theory Analysis

    Watson, Graeme; Scanlon, David

    2009-01-01

    PUBLISHED CuCrO2 is the most promising Cu-based delafossite for p-type optoelectronic devices. Despite this, little is known about the p-type conduction mechanism of this material, with both CuI/CuII and CrIII/CrIV hole mechanisms being proposed. In this article we examine the electronic structure, thermodynamic stability and the p-type defect chemistry of this ternary compound using density functional theory with three different approaches to the exchange and correlation; the generalized-...

  18. On a singular Fredholm-type integral equation arising in N=2 super-Yang–Mills theories

    In this work we study the Nekrasov–Shatashvili limit of the Nekrasov instanton partition function of Yang–Mills field theories with N=2 supersymmetry and gauge group SU(Nc). The theories are coupled with Nf flavors of fundamental matter. The equation that determines the density of eigenvalues at the leading order in the saddle-point approximation is exactly solved when Nf=2Nc. The dominating contribution to the instanton free energy is computed. The requirement that this energy is finite imposes quantization conditions on the parameters of the theory that are in agreement with analogous conditions that have been derived in previous works. The instanton energy and thus the instanton contribution to the prepotential of the gauge theory is computed in closed form.

  19. The relationship of theory of mind and executive functions to symptom type and severity in children with autism

    Joseph, Robert M.; TAGER–FLUSBERG, HELEN

    2004-01-01

    Although neurocognitive impairments in theory of mind and in executive functions have both been hypothesized to play a causal role in autism, there has been little research investigating the explanatory power of these impairments with regard to autistic symptomatology. The present study examined the degree to which individual differences in theory of mind and executive functions could explain variations in the severity of autism symptoms. Participants included 31 verbal, school-aged children ...

  20. Advancing agricultural greenhouse gas quantification*

    Olander, Lydia; Wollenberg, Eva; Tubiello, Francesco; Herold, Martin

    2013-03-01

    Agricultural Research Service 2011), which aim to improve consistency of field measurement and data collection for soil carbon sequestration and soil nitrous oxide fluxes. Often these national-level activity data and emissions factors are the basis for regional and smaller-scale applications. Such data are used for model-based estimates of changes in GHGs at a project or regional level (Olander et al 2011). To complement national data for regional-, landscape-, or field-level applications, new data are often collected through farmer knowledge or records and field sampling. Ideally such data could be collected in a standardized manner, perhaps through some type of crowd sourcing model to improve regional—and national—level data, as well as to improve consistency of locally collected data. Data can also be collected by companies working with agricultural suppliers and in country networks, within efforts aimed at understanding firm and product (supply-chain) sustainability and risks (FAO 2009). Such data may feed into various certification processes or reporting requirements from buyers. Unfortunately, this data is likely proprietary. A new process is needed to aggregate and share private data in a way that would not be a competitive concern so such data could complement or supplement national data and add value. A number of papers in this focus issue discuss issues surrounding quantification methods and systems at large scales, global and national levels, while others explore landscape- and field-scale approaches. A few explore the intersection of top-down and bottom-up data measurement and modeling approaches. 5. The agricultural greenhouse gas quantification project and ERL focus issue Important land management decisions are often made with poor or few data, especially in developing countries. Current systems for quantifying GHG emissions are inadequate in most low-income countries, due to a lack of funding, human resources, and infrastructure. Most non-Annex 1 countries

  1. Finite-size corrections in the SU(2)xSU(2) sector of type IIA string theory on AdS4xCP3

    We consider finite-size corrections in the SU(2)xSU(2) sector of type IIA string theory on AdS4xCP3, which is the string dual of the recently constructed N=6 superconformal Chern-Simons theory of Aharony, Bergman, Jafferis and Maldacena (ABJM theory). The string states we consider are in the RxS2xS2 subspace of AdS4xCP3 with an angular momentum J on CP3 being large. We compute the finite-size corrections using two different methods, one is to consider curvature corrections to the Penrose limit giving an expansion in 1/J, the other by considering a low energy expansion in λ'=λ/J2 of the string theory sigma-model, λ being the 't Hooft coupling of the dual ABJM theory. For both methods there are interesting issues to deal with. In the near-pp-wave method there is a 1/√(J) interaction term for which we use zeta-function regularization in order to compute the 1/J correction to the energy. For the low energy sigma-model expansion we have to take into account a non-trivial coupling to a non-dynamical transverse direction. We find agreement between the two methods. At order λ' and λ'2, for small λ', our results are analogous to the ones for the SU(2) sector in type IIB string theory on AdS5xS5. Instead at order λ'3 there are interactions between the two two-spheres. We compare our results with the recently proposed all-loop Bethe ansatz of Gromov and Vieira and find agreement

  2. Effect of ions on sulfuric acid-water binary particle formation: 1. Theory for kinetic- and nucleation-type particle formation and atmospheric implications

    Merikanto, Joonas; Duplissy, Jonathan; Määttänen, Anni; Henschel, Henning; Donahue, Neil M.; Brus, David; Schobesberger, Siegfried; Kulmala, Markku; Vehkamäki, Hanna

    2016-02-01

    We derive a version of Classical Nucleation Theory normalized by quantum chemical results on sulfuric acid-water hydration to describe neutral and ion-induced particle formation in the binary sulfuric acid-water system. The theory is extended to treat the kinetic regime where the nucleation free energy barrier vanishes at high sulfuric acid concentrations or low temperatures. In the kinetic regime particle formation rates become proportional to sulfuric acid concentration to second power in the neutral system or first power in the ion-induced system. We derive simple general expressions for the prefactors in kinetic-type and activation-type particle formation calculations applicable also to more complex systems stabilized by other species. The theory predicts that the binary water-sulfuric acid system can produce strong new particle formation in the free troposphere both through barrier crossing and through kinetic pathways. At cold stratospheric and upper free tropospheric temperatures neutral formation dominates the binary particle formation rates. At midtropospheric temperatures the ion-induced pathway becomes the dominant mechanism. However, even the ion-induced binary mechanism does not produce significant particle formation in warm boundary layer conditions, as it requires temperatures below 0°C to take place at atmospheric concentrations. The theory successfully reproduces the characteristics of measured charged and neutral binary particle formation in CERN CLOUD3 and CLOUD5 experiments, as discussed in a companion paper.

  3. Training load quantification in triathlon

    2011-01-01

    There are different Indices of Training Stress of varying complexity, to quantification Training load. Examples include the training impulse (TRIMP), the session (RPE), Lucia’s TRIMP or Summated Zone Score. But the triathlon, a sport to be combined where there are interactions between different segments, is a complication when it comes to quantify the training. The aim of this paper is to review current methods of quantification, and to propose a scale to quantify the training load in triathl...

  4. Method of moments for the continuous transition between the Brillouin-Wigner-type and Rayleigh-Schroumldinger-type multireference coupled cluster theories

    Pittner, Jiří; Piecuch, P.

    2009-01-01

    Roč. 107, 8-12 (2009), s. 1209-1221. ISSN 0026-8976 R&D Projects: GA ČR GA203/07/0070; GA AV ČR 1ET400400413; GA AV ČR KSK4040110 Institutional research plan: CEZ:AV0Z40400503 Keywords : multireference coupled cluster theory * method of moments of coupled cluster equations * state-universal multireference coupled cluster approach Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 1.634, year: 2009

  5. Nitrogen quantification with SNMS

    Goschnick, J.; Natzeck, C.; Sommer, M.

    1999-04-01

    Plasma-based secondary neutral mass spectrometry (plasma SNMS) is a powerful analytical method for determining the elemental concentrations of almost any kind of material at low cost by using a cheap quadrupole mass filter. However, a quadrupole-based mass spectrometer is limited to nominal mass resolution. Atomic signals are sometimes superimposed by molecular signals (2 or 3 atomic clusters such as CH +, CH 2+ or metal oxide clusters) and/or intensities of double-charged species. Especially in the case of nitrogen several interferences can impede the quantification. This article reports on methods to recognize and deconvolute superpositions of N + with CH 2+, Li 2+, and Si 2+ at mass 14 D (Debye) occurring during analysis of organic and inorganic substances. The recognition is based on the signal pattern of N +, Li +, CH +, and Si +. The latter serve as indicators for a probable interference of molecular or double-charged species with N on mass 14 D. The subsequent deconvolution use different shapes of atomic and cluster kinetic energy distributions (kEDs) to determine the quantities of the intensity components by a linear fit of N + and non-atomic kEDs obtained from several organic and inorganic standards into the measured kED. The atomic intensity fraction yields a much better nitrogen concentration than the total intensity of mass 14 D after correction.

  6. Aharonov-Bohm Effect for Bound States on the Confinement of a Relativistic Scalar Particle to a Coulomb-Type Potential in Kaluza-Klein Theory

    E. V. B. Leite

    2015-01-01

    Full Text Available Based on the Kaluza-Klein theory, we study the Aharonov-Bohm effect for bound states for a relativistic scalar particle subject to a Coulomb-type potential. We introduce this scalar potential as a modification of the mass term of the Klein-Gordon equation, and a magnetic flux through the line element of the Minkowski spacetime in five dimensions. Then, we obtain the relativistic bound states solutions and calculate the persistent currents.

  7. The field and Killing spinor equations of M-theory and type IIA/IIB supergravity in coordinate-free notation

    Hamilton, M J D

    2016-01-01

    We review the actions of the supergravity theory in eleven dimensions as well as the type IIA and IIB supergravities in ten dimensions and derive the bosonic equations of motion in a coordinate-free notation. We also consider the existence of supersymmetries and the associated generalized Killing spinor equations. The aim of this note is to serve as a formulary and make the equations of supergravity more easily accessible to mathematicians.

  8. Application of the perturbation theory-differential formalism-for sensitivity analysis in steam generators of PWR type nuclear power plants

    An homogeneous model which simulates the stationary behavior of steam generators of PWR type reactors and uses the differential formalism of perturbation theory for analysing sensibility of linear and non-linear responses, is presented. The PERGEVAP computer code to calculate the temperature distribution in the steam generator and associated importance function, is developed. The code also evaluates effects of the thermohydraulic parameter variation on selected functionals. The obtained results are compared with results obtained by GEVAP computer code . (M.C.K.)

  9. Curing theory of A_f-A_g type free radical polymerization (Ⅱ)——Characterization of network structural parameters

    王海军; 吕中元; 黄旭日; 李泽生; 唐敖庆

    1999-01-01

    By means of the polymer statistical theory, the A_f-A_g type nonlinear free radical polymerization is investigated to give the number of effective elastic chains, the number of effective elastic mers and the average length for the elastic chains. The corresponding quantities for the dangling chains, the number of effective cross-linkage and the modulus are also obtained. Furthermore, the number- and weight-fractions of elastic chains are deduced.

  10. Uncertainty quantification and stochastic modeling with Matlab

    Souza de Cursi, Eduardo

    2015-01-01

    Uncertainty Quantification (UQ) is a relatively new research area which describes the methods and approaches used to supply quantitative descriptions of the effects of uncertainty, variability and errors in simulation problems and models. It is rapidly becoming a field of increasing importance, with many real-world applications within statistics, mathematics, probability and engineering, but also within the natural sciences. Literature on the topic has up until now been largely based on polynomial chaos, which raises difficulties when considering different types of approximation and does no

  11. Theory of The Generalized Bernoulli-Hurwitz Numbers for The Algebraic Functions of Cyclotomic Type and The Universal Bernoulli Numbers

    Ônishi, Yoshihiro

    2004-01-01

    Hurwitz numbers are the Laurent coefficients of an elliptic function $\\wp(u)$ of cyclotomic type, and they are natural generalization of the Bernoulli numbers. This paper gives new generalization of Bernoulli and Hurwitz numbers for higher genus cases. They satisfy completely von Staudt-Clausen type theorem, an extension of von Staudt second theorem, and Kummer type congruence relation. The present paper is revised and combined version of math.NT/0304377 and math.NT/0312178 containing many nu...

  12. Perturbation theory

    After noting some advantages of using perturbation theory some of the various types are related on a chart and described, including many-body nonlinear summations, quartic force-field fit for geometry, fourth-order correlation approximations, and a survey of some recent work. Alternative initial approximations in perturbation theory are also discussed. 25 references

  13. Uncertainty Quantification in Climate Modeling

    Sargsyan, K.; Safta, C.; Berry, R.; Debusschere, B.; Najm, H.

    2011-12-01

    We address challenges that sensitivity analysis and uncertainty quantification methods face when dealing with complex computational models. In particular, climate models are computationally expensive and typically depend on a large number of input parameters. We consider the Community Land Model (CLM), which consists of a nested computational grid hierarchy designed to represent the spatial heterogeneity of the land surface. Each computational cell can be composed of multiple land types, and each land type can incorporate one or more sub-models describing the spatial and depth variability. Even for simulations at a regional scale, the computational cost of a single run is quite high and the number of parameters that control the model behavior is very large. Therefore, the parameter sensitivity analysis and uncertainty propagation face significant difficulties for climate models. This work employs several algorithmic avenues to address some of the challenges encountered by classical uncertainty quantification methodologies when dealing with expensive computational models, specifically focusing on the CLM as a primary application. First of all, since the available climate model predictions are extremely sparse due to the high computational cost of model runs, we adopt a Bayesian framework that effectively incorporates this lack-of-knowledge as a source of uncertainty, and produces robust predictions with quantified uncertainty even if the model runs are extremely sparse. In particular, we infer Polynomial Chaos spectral expansions that effectively encode the uncertain input-output relationship and allow efficient propagation of all sources of input uncertainties to outputs of interest. Secondly, the predictability analysis of climate models strongly suffers from the curse of dimensionality, i.e. the large number of input parameters. While single-parameter perturbation studies can be efficiently performed in a parallel fashion, the multivariate uncertainty analysis

  14. Quantification and Negation in Event Semantics

    Lucas Champollion

    2010-12-01

    Full Text Available Recently, it has been claimed that event semantics does not go well together with quantification, especially if one rejects syntactic, LF-based approaches to quantifier scope. This paper shows that such fears are unfounded, by presenting a simple, variable-free framework which combines a Neo-Davidsonian event semantics with a type-shifting based account of quantifier scope. The main innovation is that the event variable is bound inside the verbal denotation, rather than at sentence level by existential closure. Quantifiers can then be interpreted in situ. The resulting framework combines the strengths of event semantics and type-shifting accounts of quantifiers and thus does not force the semanticist to posit either a default underlying word order or a syntactic LF-style level. It is therefore well suited for applications to languages where word order is free and quantifier scope is determined by surface order. As an additional benefit, the system leads to a straightforward account of negation, which has also been claimed to be problematic for event-based frameworks.ReferencesBarker, Chris. 2002. ‘Continuations and the nature of quantification’. Natural Language Semantics 10: 211–242.http://dx.doi.org/10.1023/A:1022183511876Barker, Chris & Shan, Chung-chieh. 2008. ‘Donkey anaphora is in-scope binding’. Semantics and Pragmatics 1: 1–46.Beaver, David & Condoravdi, Cleo. 2007. ‘On the logic of verbal modification’. In Maria Aloni, Paul Dekker & Floris Roelofsen (eds. ‘Proceedings of the Sixteenth Amsterdam Colloquium’, 3–9. Amsterdam, Netherlands: University of Amsterdam.Beghelli, Filippo & Stowell, Tim. 1997. ‘Distributivity and negation: The syntax of each and every’. In Anna Szabolcsi (ed. ‘Ways of scope taking’, 71–107. Dordrecht, Netherlands: Kluwer.Brasoveanu, Adrian. 2010. ‘Modified Numerals as Post-Suppositions’. In Maria Aloni, Harald Bastiaanse, Tikitu de Jager & Katrin Schulz (eds. ‘Logic, Language

  15. Statistical Mechanics Of Cracks Dualities In Supersymmetric Field Theories Orientifolds Of Type Iib Strings With Discrete B Flux

    Buchel, A S

    1999-01-01

    In the first part of this thesis we study a class of models for brittle fracture: elastic theory models which allow for cracks but not for plastic flow. We show that these models exhibit, at all finite temperatures, a transition to fracture under applied load. We study this transition at low temperature for small tension. We discuss the appropriate thermodynamic limit of these theories: a large class of boundary conditions is identified for which the energy release for a crack becomes independent of the macroscopic shape of the material. We prove that the energy release in an isotropically stretched material due to the creation of an arbitrary curvy cut is the same to cubic order as the energy release for the straight cut with the same end points...

  16. Application of perturbation theory to sensitivity calculations of PWR type reactor cores using the two-channel model

    Sensitivity calculations are very important in design and safety of nuclear reactor cores. Large codes with a great number of physical considerations have been used to perform sensitivity studies. However, these codes need long computation time involving high costs. The perturbation theory has constituted an efficient and economical method to perform sensitivity analysis. The present work is an application of the perturbation theory (matricial formalism) to a simplified model of DNB (Departure from Nucleate Boiling) analysis to perform sensitivity calculations in PWR cores. Expressions to calculate the sensitivity coefficients of enthalpy and coolant velocity with respect to coolant density and hot channel area were developed from the proposed model. The CASNUR.FOR code to evaluate these sensitivity coefficients was written in Fortran. The comparison between results obtained from the matricial formalism of perturbation theory with those obtained directly from the proposed model makes evident the efficiency and potentiality of this perturbation method for nuclear reactor cores sensitivity calculations (author). 23 refs, 4 figs, 7 tabs

  17. Bianchi type-V cosmological models with perfect fluid and heat flow in Saez–Ballester theory

    Shri Ram; M Zeyauddin; C P Singh

    2009-02-01

    In this paper we discuss the variation law for Hubble's parameter with average scale factor in a spatially homogeneous and anisotropic Bianchi type-V space-time model, which yields constant value of the deceleration parameter. We derive two laws of variation of the average scale factor with cosmic time, one is of power-law type and the other is of exponential form. Exact solutions of Einstein field equations with perfect fluid and heat conduction are obtained for Bianchi type-V space-time in these two types of cosmologies. In the cosmology with the power-law, the solutions correspond to a cosmological model which starts expanding from the singular state with positive deceleration parameter. In the case of exponential cosmology, we present an accelerating non-singular model of the Universe. We find that the constant value of deceleration parameter is reasonable for the present day Universe and gives an appropriate description of evolution of Universe. We have also discussed different types of physical and kinematical behaviour of the models in these two types of cosmologies.

  18. Mathematical model for biomolecular quantification using surface-enhanced Raman spectroscopy based signal intensity distributions

    Palla, Mirko; Bosco, Filippo Giacomo; Yang, Jaeyoung; Rindzevicius, Tomas; Alstrøm, Tommy Sonne; Schmidt, Michael Stenbak; Lin, Qiao; Ju, Jingyue; Boisen, Anja

    This paper presents the development of a novel statistical method for quantifying trace amounts of biomolecules by surface-enhanced Raman spectroscopy (SERS) using a rigorous, single molecule (SM) theory based mathematical derivation. Our quantification framework could be generalized for planar...... SERS substrates, in which the nanostructured features can be approximated as a closely spaced electromagnetic dimer problem. The potential for SM detection was also shown, which opens up an exciting opportunity in the field of SERS quantification....

  19. The Types of Axisymmetric Exact Solutions Closely Related to n-SOLITONS for Yang-Mills Theory

    Zhong, Zai Zhe

    In this letter, we point out that if a symmetric 2×2 real matrix M(ρ,z) obeys the Belinsky-Zakharov equation and |det(M)|=1, then an axisymmetric Bogomol'nyi field exact solution for the Yang-Mills-Higgs theory can be given. By using the inverse scattering technique, some special Bogomol'nyi field exact solutions, which are closely related to the true solitons, are generated. In particular, the Schwarzschild-like solution is a two-soliton-like solution.

  20. Quantification of adipose tissue insulin sensitivity

    Søndergaard, Esben; Jensen, Michael D

    2016-01-01

    In metabolically healthy humans, adipose tissue is exquisitely sensitive to insulin. Similar to muscle and liver, adipose tissue lipolysis is insulin resistant in adults with central obesity and type 2 diabetes. Perhaps uniquely, however, insulin resistance in adipose tissue may directly contribute...... to development of insulin resistance in muscle and liver because of the increased delivery of free fatty acids to those tissues. It has been hypothesized that insulin adipose tissue resistance may precede other metabolic defects in obesity and type 2 diabetes. Therefore, precise and reproducible...... quantification of adipose tissue insulin sensitivity, in vivo, in humans, is an important measure. Unfortunately, no consensus exists on how to determine adipose tissue insulin sensitivity. We review the methods available to quantitate adipose tissue insulin sensitivity and will discuss their strengths and...

  1. Quantification of adipose tissue insulin sensitivity.

    Søndergaard, Esben; Jensen, Michael D

    2016-06-01

    In metabolically healthy humans, adipose tissue is exquisitely sensitive to insulin. Similar to muscle and liver, adipose tissue lipolysis is insulin resistant in adults with central obesity and type 2 diabetes. Perhaps uniquely, however, insulin resistance in adipose tissue may directly contribute to development of insulin resistance in muscle and liver because of the increased delivery of free fatty acids to those tissues. It has been hypothesized that insulin adipose tissue resistance may precede other metabolic defects in obesity and type 2 diabetes. Therefore, precise and reproducible quantification of adipose tissue insulin sensitivity, in vivo, in humans, is an important measure. Unfortunately, no consensus exists on how to determine adipose tissue insulin sensitivity. We review the methods available to quantitate adipose tissue insulin sensitivity and will discuss their strengths and weaknesses. PMID:27073214

  2. Pressure-induced phase transformation in zircon-type orthovanadate SmVO4 from experiment and theory

    Popescu, C.; Garg, Alka B; Errandonea, D.; Sans, J.A.; Rodriguez-Hernandez, P.; Radescu, S.; Munoz, A.; Achary, S N; Tyagi, A. K.

    2016-01-01

    The compression behavior of zircon-type samarium orthovanadate, SmVO4, has been investigated using synchrotron-based powder x-ray diffraction and ab-initio calculations up to 21 GPa. The results indicate the instability of ambient zircon phase at around 6 GPa, which transforms to a high-density scheelite-type phase. The high-pressure phase remains stable up to 21 GPa, the highest pressure reached in the present investigations. On pressure release, the scheelite phase is recovered. Crystal str...

  3. MAMA Software Features: Quantification Verification Documentation-1

    Ruggiero, Christy E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Porter, Reid B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-05-21

    This document reviews the verification of the basic shape quantification attributes in the MAMA software against hand calculations in order to show that the calculations are implemented mathematically correctly and give the expected quantification results.

  4. Study on exploration theory and SAR technology for interlayer oxidation zone sandstone type uranium deposit and its application in Eastern Jungar Basin

    Started with analyzing the features of metallogenetic epoch and space distribution of typical interlayer oxidation zone sandstone type uranium deposit both in China and abroad and their relations of basin evolution, the authors have proposed the idea that the last unconformity mainly controls the metallogenetic epoch and the strength of structure activity after the last unconformity determines the deposit space. An exploration theory with the kernel from new events to the old one is put forward. The means and method to use SAR technology to identify ore-controlling key factors are discussed. An application study in Eastern Jungar Basin is performed

  5. A shear deformable theory of laminated composite shallow shell-type panels and their response analysis. II - Static response

    Khdeir, A. A.; Librescu, L.; Frederick, D.

    1989-01-01

    In the second part of this paper, by using the static counterparts of the governing equations derived in Librescu (1989), the static response of shallow composite shell-type panels subjected to a sinusoidal transverse load is investigated. The numerical applications, encompassing a large number of boundary conditions and various lamination schemes, allow one to obtain some conclusions which are formulated in the paper.

  6. Theory of quantum frequency conversion and type-II parametric down-conversion in the high-gain regime

    Frequency conversion (FC) and type-II parametric down-conversion (PDC) processes serve as basic building blocks for the implementation of quantum optical experiments: type-II PDC enables the efficient creation of quantum states such as photon-number states and Einstein–Podolsky–Rosen (EPR)-states. FC gives rise to technologies enabling efficient atom–photon coupling, ultrafast pulse gates and enhanced detection schemes. However, despite their widespread deployment, their theoretical treatment remains challenging. Especially the multi-photon components in the high-gain regime as well as the explicit time-dependence of the involved Hamiltonians hamper an efficient theoretical description of these nonlinear optical processes. In this paper, we investigate these effects and put forward two models that enable a full description of FC and type-II PDC in the high-gain regime. We present a rigorous numerical model relying on the solution of coupled integro-differential equations that covers the complete dynamics of the process. As an alternative, we develop a simplified model that, at the expense of neglecting time-ordering effects, enables an analytical solution. While the simplified model approximates the correct solution with high fidelity in a broad parameter range, sufficient for many experimental situations, such as FC with low efficiency, entangled photon-pair generation and the heralding of single photons from type-II PDC, our investigations reveal that the rigorous model predicts a decreased performance for FC processes in quantum pulse gate applications and an enhanced EPR-state generation rate during type-II PDC, when EPR squeezing values above 12 dB are considered. (paper)

  7. XPS quantification of the hetero-junction interface energy

    Ma, Z.S. [Key Laboratory of Low-Dimensional Materials and Application Technology of Ministry of Education, Institute for Quantum Engineering and Micro-Nano Energy Technology and Faculty of Materials, Optoelectronics and Physics, Xiangtan University, Hunan 411105 (China); Wang Yan [Key Laboratory of Low-Dimensional Materials and Application Technology of Ministry of Education, Institute for Quantum Engineering and Micro-Nano Energy Technology and Faculty of Materials, Optoelectronics and Physics, Xiangtan University, Hunan 411105 (China); School of Information and Electronic Engineering, Hunan University of Science and Technology, Hunan 411201 (China); Huang, Y.L.; Zhou, Z.F. [Key Laboratory of Low-Dimensional Materials and Application Technology of Ministry of Education, Institute for Quantum Engineering and Micro-Nano Energy Technology and Faculty of Materials, Optoelectronics and Physics, Xiangtan University, Hunan 411105 (China); Zhou, Y.C., E-mail: zhouyc@xtu.edu.cn [Key Laboratory of Low-Dimensional Materials and Application Technology of Ministry of Education, Institute for Quantum Engineering and Micro-Nano Energy Technology and Faculty of Materials, Optoelectronics and Physics, Xiangtan University, Hunan 411105 (China); Zheng Weitao [School of Materials Science, Jilin University, Changchun 130012 (China); Sun, Chang Q. [Key Laboratory of Low-Dimensional Materials and Application Technology of Ministry of Education, Institute for Quantum Engineering and Micro-Nano Energy Technology and Faculty of Materials, Optoelectronics and Physics, Xiangtan University, Hunan 411105 (China); School of Materials Science, Jilin University, Changchun 130012 (China); School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798 (Singapore)

    2013-01-15

    Highlights: Black-Right-Pointing-Pointer Quantum entrapment or polarization dictates the performance of dopant, impurity, interface, alloy and compounds. Black-Right-Pointing-Pointer Interface bond energy, energy density, and atomic cohesive energy can be determined using XPS and our BOLS theory. Black-Right-Pointing-Pointer Presents a new and reliable method for catalyst design and identification. Black-Right-Pointing-Pointer Entrapment makes CuPd to be a p-type catalyst and polarization derives AgPd as an n-type catalyst. - Abstract: We present an approach for quantifying the heterogeneous interface bond energy using X-ray photoelectron spectroscopy (XPS). Firstly, from analyzing the XPS core-level shift of the elemental surfaces we obtained the energy levels of an isolated atom and their bulk shifts of the constituent elements for reference; then we measured the energy shifts of the specific energy levels upon interface alloy formation. Subtracting the referential spectrum from that collected from the alloy, we can distil the interface effect on the binding energy. Calibrated based on the energy levels and their bulk shifts derived from elemental surfaces, we can derive the bond energy, energy density, atomic cohesive energy, and free energy at the interface region. This approach has enabled us to clarify the dominance of quantum entrapment at CuPd interface and the dominance of polarization at AgPd and BeW interfaces, as the origin of interface energy change. Developed approach not only enhances the power of XPS but also enables the quantification of the interface energy at the atomic scale that has been an issue of long challenge.

  8. A recipe for EFT uncertainty quantification in nuclear physics

    The application of effective field theory (EFT) methods to nuclear systems provides the opportunity to rigorously estimate the uncertainties originating in the nuclear Hamiltonian. Yet this is just one source of uncertainty in the observables predicted by calculations based on nuclear EFTs. We discuss the goals of uncertainty quantification in such calculations and outline a recipe to obtain statistically meaningful error bars for their predictions. We argue that the different sources of theory error can be accounted for within a Bayesian framework, as we illustrate using a toy model. (paper)

  9. Quantification of natural phenomena

    The science is like a great spider's web in which unexpected connections appear and therefore it is frequently difficult to already know the consequences of new theories on those existent. The physics is a clear example of this. The Newton mechanics laws describe the physical phenomena observable accurately by means of our organs of the senses or by means of observation teams not very sophisticated. After their formulation at the beginning of the XVIII Century, these laws were recognized in the scientific world as a mathematical model of the nature. Together with the electrodynamics law, developed in the XIX century, and the thermodynamic one constitutes what we call the classic physics. The state of maturity of the classic physics at the end of last century it was such that some scientists believed that the physics was arriving to its end obtaining a complete description of the physical phenomena. The spider's web of the knowledge was supposed finished, or at least very near its termination. It ended up saying, in arrogant form, that if the initial conditions of the universe were known, we could determine the state of the same one in any future moment. Two phenomena related with the light would prove in firm form that mistaken that they were, creating unexpected connections in the great spider's web of the knowledge and knocking down part of her. The thermal radiation of the bodies and the fact that the light spreads to constant speed in the hole, without having an absolute system of reference with regard to which this speed is measured, they constituted the decisive factors in the construction of a new physics. The development of sophisticated of measure teams gave access to more precise information and it opened the microscopic world to the observation and confirmation of existent theories

  10. An analysis of EH- type linear based on two- dimensional heterotic system string theory%对杂化弦EH型线性系统的分析

    魏益焕

    2011-01-01

    由文献[4]中方程(2.25)-(2.31b)给出了对杂化弦EH型线性系统的分析。结果表明该线性系统等同于由文献[4]中方程(2.17)-(2.24b)给出的EH型线性系统。%An analysis is made of the EH - type linear system based on two - dimensional heterotic string theory, as is indicated in the equation of (2.25) - (2.31 b) in Bibliography [ 4 ]. The result shows that this system is equivalent to the EH -type linear system in the equations of (2.17) - (2.24b) in Bibliography [4].

  11. First-order theory of electrical focusing in cyclotron-type two-dimensional lenses with static and time-varying potentials

    The potential distribution in cyclotron-type gaps with liner (outer electrodes at ground potential) is determined via Schwarz-Christoffel transformation as well as by computer analysis (relaxation method). First-order focusing formulas for both static as well as time-varying potentials are derived. In addition exact calculations were carried out by direct numerical integration of the equations of motion with a computer program. The numerical data permitted an accurate evaluation of the validity of the analytical approximation as well as further improvement of the theoretical formulas. Focusing relations are presented in a generalized form which shows the scaling laws and is readily applicable to different types of particles, energies or lens geometries. As an example, the theory is applied in the axial motion of ions in a cyclotron

  12. Preference for a Vanishingly Small Cosmological Constant in Supersymmetric Vacua in a Type IIB String Theory Model

    Sumitomo, Yoske

    2012-01-01

    We study the probability distribution P(\\Lambda) of the cosmological constant \\Lambda in a specific set of KKLT type models of supersymmetric IIB vacua. P(\\Lambda) is divergent at \\Lambda =0^- and the likely value of \\Lambda drops exponentially as the number of complex structure moduli h^{2,1} increases. Also, owing to the hierarchical and approximate no-scale structure, the probability of having a positive Hessian (mass squared matrix) approaches unity as h^{2,1} increases.

  13. Pressure-induced phase transformation in zircon-type orthovanadate SmVO4 from experiment and theory

    Popescu, C.; Garg, Alka B.; Errandonea, D.; Sans, J. A.; Rodriguez-Hernández, P.; Radescu, S.; Muñoz, A.; Achary, S. N.; Tyagi, A. K.

    2016-01-01

    The compression behavior of zircon-type samarium orthovanadate, SmVO4, has been investigated using synchrotron-based powder x-ray diffraction and ab initio calculations of up to 21 GPa. The results indicate the instability of ambient zircon phase at around 6 GPa, which transforms to a high-density scheelite-type phase. The high-pressure phase remains stable up to 21 GPa, the highest pressure reached in the present investigations. On pressure release, the scheelite phase is recovered. The crystal structure of the high-pressure phase and the equations of state for the zircon- and scheelite-type phases have been determined. Various compressibilities, such as the bulk, axial and bond compressibilities, estimated from the experimental data are found to be in good agreement with the results obtained from theoretical calculations. The calculated elastic constants show that the zircon structure becomes mechanically unstable beyond the transition pressure. Overall there is good agreement between the experimental and theoretical findings.

  14. Pressure-induced phase transformation in zircon-type orthovanadate SmVO4 from experiment and theory.

    Popescu, C; Garg, Alka B; Errandonea, D; Sans, J A; Rodriguez-Hernández, P; Radescu, S; Muñoz, A; Achary, S N; Tyagi, A K

    2016-01-27

    The compression behavior of zircon-type samarium orthovanadate, SmVO4, has been investigated using synchrotron-based powder x-ray diffraction and ab initio calculations of up to 21 GPa. The results indicate the instability of ambient zircon phase at around 6 GPa, which transforms to a high-density scheelite-type phase. The high-pressure phase remains stable up to 21 GPa, the highest pressure reached in the present investigations. On pressure release, the scheelite phase is recovered. The crystal structure of the high-pressure phase and the equations of state for the zircon- and scheelite-type phases have been determined. Various compressibilities, such as the bulk, axial and bond compressibilities, estimated from the experimental data are found to be in good agreement with the results obtained from theoretical calculations. The calculated elastic constants show that the zircon structure becomes mechanically unstable beyond the transition pressure. Overall there is good agreement between the experimental and theoretical findings. PMID:26733093

  15. THE RELATIONSHIP BETWEEN HERZBERG’S MOTIVATION THEORY AND THE LEADERSHIP TYPES: AN APPLICATION IN BANKING SECTOR

    KILIÇ, Recep; Çoban, Mehmet

    2015-01-01

    This paper aims to explore the effects of leadership types on personal motivation in banking sector. The methodology used is survey based. In this study, the group who fill the survey is consist of bank employees in Bandırma. The group was selected randomly. In this study, Herzberg’s two factor of Motive and Hygiene applied seperately. Firstly, the effects of leadership styles on motive factors was tested. Then the effects of leadership styles on hygiene factors was tested. Correlation analyz...

  16. Generation of non-classical correlated photon pairs via a ladder-type atomic configuration: theory and experiment

    Ding, Dong-Sheng; Zhou, Zhi-Yuan; Shi, Bao-Sen; Zou, Xu-Bo; Guo, Guang-Can

    2012-01-01

    We experimentally generate a non-classical correlated two-color photon pair at 780 and 1529.4 nm in a ladder-type configuration using a hot 85Rb atomic vapor with the production rate of ~107/s. The non-classical correlation between these two photons is demonstrated by strong violation of Cauchy-Schwarz inequality by the factor R=48+-12. Besides, we experimentally investigate the relations between the correlation and some important experimental parameters such as the single-photon detuning, th...

  17. Preference for a vanishingly small cosmological constant in supersymmetric vacua in a Type IIB string theory model

    We study the probability distribution P(Λ) of the cosmological constant Λ in a specific set of KKLT type models of supersymmetric IIB vacua. We show that, as we sweep through the quantized flux values in this flux compactification, P(Λ) behaves divergent at Λ=0− and the median magnitude of Λ drops exponentially as the number of complex structure moduli h2,1 increases. Also, owing to the hierarchical and approximate no-scale structure, the probability of having a positive Hessian (mass-squared matrix) approaches unity as h2,1 increases

  18. Statistical theory for hydrogen bonding fluid system of AaDd type (Ⅱ): Properties of hydrogen bonding networks

    WANG HaiJun; HONG XiaoZhong; GU Fang; BA XinWu

    2007-01-01

    Making use of the invariant property of the equilibrium size distribution of the hydrogen bonding clusters formed in hydrogen bonding system of AaDd type, the analytical expressions of the free energy in pregel and postgel regimes are obtained. Then the gel free energy and the scaling behavior of the number of hydrogen bonds in gel phase near the critical point are investigated to give the corresponding scaling exponents and scaling law. Meanwhile, some properties of intermolecular and intramolecular hydrogen bonds in the system, sol and gel phases are discussed. As a result, the explicit relationship between the number of intramolecular hydrogen bonds and hydrogen bonding degree is obtained.

  19. The synthesis and characterization of Ag-N dual-doped p-type ZnO: experiment and theory.

    Duan, Li; Wang, Pei; Yu, Xiaochen; Han, Xiao; Chen, Yongnan; Zhao, Peng; Li, Donglin; Yao, Ran

    2014-03-01

    Ag-N dual-doped ZnO films have been fabricated by a chemical bath deposition method. The p-type conductivity of the dual-doped ZnO:(Ag, N) is stable over a long period of time, and the hole concentration in the ZnO:(Ag, N) is much higher than that in mono-doped ZnO:Ag or ZnO:N. We found that this is because AgZn-NO complex acceptors can be formed in ZnO:(Ag, N). First-principles calculations show that the complex acceptors generate a fully occupied band above the valance band maximum, so the acceptor levels become shallower and the hole concentration is increased. Furthermore, the binding energy of the Ag-N complex in ZnO is negative, so ZnO:(Ag, N) can be stable. These results indicate that the Ag-N dual-doping may be expected to be a potential route to achieving high-quality p-type ZnO for use in a variety of devices. PMID:24448605

  20. An explanatory model of adjustment to type I diabetes based on attachment, coping, and self-regulation theories.

    Bazzazian, S; Besharat, M A

    2012-01-01

    The aim of this study was to develop and test a model of adjustment to type I diabetes. Three hundred young adults (172 females and 128 males) with type I diabetes were asked to complete the Adult Attachment Inventory (AAI), the Brief Illness Perception Questionnaire (Brief IPQ), Task-oriented subscale of the Coping Inventory for Stressful Situations (CISS), D-39, and well-being subscale of the Mental Health Inventory (MHI). HbA1c was obtained from laboratory examination. Results from structural equation analysis partly supported the hypothesized model. Secure and avoidant attachment styles were found to have effects on illness perception, ambivalent attachment style did not have significant effect on illness perception. Three attachment styles had significant effect on task-oriented coping strategy. Avoidant attachment had negative direct effect on adjustment too. Regression effects of illness perception and task-oriented coping strategy on adjustment were positive. Therefore, positive illness perception and more usage of task-oriented coping strategy predict better adjustment to diabetes. So, the results confirmed the theoretical bases and empirical evidence of effectiveness of attachment styles in adjustment to chronic disease and can be helpful in devising preventive policies, determining high-risk maladjusted patients, and planning special psychological treatment. PMID:21678193

  1. Predictive Game Theory

    Wolpert, David H.

    2005-01-01

    Probability theory governs the outcome of a game; there is a distribution over mixed strat.'s, not a single "equilibrium". To predict a single mixed strategy must use our loss function (external to the game's players. Provides a quantification of any strategy's rationality. Prove rationality falls as cost of computation rises (for players who have not previously interacted). All extends to games with varying numbers of players.

  2. Statistical theory for hydrogen bonding fluid system of AaDd type (I): The geometrical phase transition

    WANG Haijun; HONG Xiaozhong; GU Fang; BA Xinwu

    2006-01-01

    The influence of hydrogen bonds on the physical and chemical properties of hydrogen bonding fluid system of AaDd type is investigated from two viewpoints by the principle of statistical mechanics. In detail, we proposed two new ways that can be used to obtain the equilibrium size distribution of the hydrogen bonding clusters, and derived the analytical expression of a relationship between the hydrogen bonding free energy and hydrogen bonding degree. For the nonlinear hydrogen bonding systems, it is shown that the sol-gel phase transition can take place under proper conditions, which is further proven to be a kind of geometrical phase transition rather than a thermodynamic one. Moreover, several problems associated with the geometrical phase transition and liquid-solid phase transition in nonlinear hydrogen bonding systems are discussed.

  3. The theory of the measurement of the London penetration depth in uniaxial type II superconductors by muon spin rotation

    The effect of anisotropy on the measurement, by muon spin rotation, of the London penetration depth in the high Tc uniaxial type II superconductors is considered in detail. Expressions are derived which will allow the principal penetration depths, λ1 and λ2, to be determined using measurements of the μSR line width from single crystals. For polycrystalline, powder or sintered, samples an expression is derived which will allow an effective penetration depth, λeff, to be determined from the measured μSR line width. Further, it is shown that for all anisotropy ratios, λ2/λ1, greater than five λ1 ∼ 0.81λeff. (author)

  4. Generation of non-classical correlated photon pairs via a ladder-type atomic configuration: theory and experiment.

    Ding, Dong-Sheng; Zhou, Zhi-Yuan; Shi, Bao-Sen; Zou, Xu-Bo; Guo, Guang-Can

    2012-05-01

    We experimentally generate a non-classical correlated two-color photon pair at 780 and 1529.4 nm in a ladder-type configuration using a hot 85Rb atomic vapor with the production rate of ~10(7)/s. The non-classical correlation between these two photons is demonstrated by strong violation of Cauchy-Schwarz inequality by the factor R = 48 ± 12. Besides, we experimentally investigate the relations between the correlation and some important experimental parameters such as the single-photon detuning, the powers of pumps. We also make a theoretical analysis in detail and the theoretical predictions are in reasonable agreement with our experimental results. PMID:22565763

  5. Statistical theory for hydrogen bonding fluid system of AaDd type (Ⅲ): Equation of state and fluctuations

    WANG HaiJun; GU Fang; HONG XiaoZhong; BA XinWu

    2007-01-01

    The equation of the state of the hydrogen bonding fluid system of AaDd type is studied by the principle of statistical mechanics. The influences of hydrogen bonds on the equation of state of the system are obtained based on the change in volume due to hydrogen bonds. Moreover, the number density fluctuations of both molecules and hydrogen bonds as well as their spatial correlation property are investigated. Furthermore, an equation describing relation between the number density correlation function of "molecules-hydrogen bonds" and that of molecules and hydrogen bonds is derived. As application,taking the van der Waals hydrogen bonding fluid as an example, we considered the effect of hydrogen bonds on its relevant statistical properties.

  6. The quantification of hazards

    The seventh chapter deals in detail with the means and methods allowing to quantify the objective dimension and scope of a hazard in concrete situations. Source and type of possible damage and exposure path determine the detection and perception of hazards. Risk assessment requires the determination of the dose-effect relationship of the hazard situation and of the dimension and the probability of the damage. Risk assessments are exemplified: influenza epidemic; accidents in a nuclear power plant; the risk for the population emanating from normal nuclear power plant operation. The author concludes that subjective elements inevitably enter into any risk assessment - though to a varying extent - and, hence, that objectivity is but relative. (HSCH)

  7. Structure and dynamics of Xn-type clusters (n = 3, 4, 6) from spontaneous symmetry breaking theory

    On the basis of three symmetries of nature, homogeneity and isotropy of space and indistinguishability of identical particles, we have found a group of coordinate transformations that leaves invariant the electronic energy and the potential energy of nuclei in every molecule subjected to no external fields. From these transformations we derived the formula for the dynamical representation and proved that every molecule has at least one Raman-active, totally symmetric normal mode of vibration. As an example, we studied stable configurations and dynamics of Xn-type molecules (clusters), n = 3, 4, 6, within symmetry-adapted, second-order expansion of the electronic energy with respect to nuclear coordinates, around the united atom. Within this approximation, for a positive coefficient in the expansion, a homonuclear three- (four-, six-) atomic cluster has a stable configuration of D3h (Td, Oh) symmetry. Our calculated mutual ratios of vibrational frequencies for clusters with these geometries are in reasonable agreement with experiment. (paper)

  8. Quantum theory of open systems based on stochastic differential equations of generalized Langevin (non-Wiener) type

    It is shown that the effective Hamiltonian representation, as it is formulated in author’s papers, serves as a basis for distinguishing, in a broadband environment of an open quantum system, independent noise sources that determine, in terms of the stationary quantum Wiener and Poisson processes in the Markov approximation, the effective Hamiltonian and the equation for the evolution operator of the open system and its environment. General stochastic differential equations of generalized Langevin (non-Wiener) type for the evolution operator and the kinetic equation for the density matrix of an open system are obtained, which allow one to analyze the dynamics of a wide class of localized open systems in the Markov approximation. The main distinctive features of the dynamics of open quantum systems described in this way are the stabilization of excited states with respect to collective processes and an additional frequency shift of the spectrum of the open system. As an illustration of the general approach developed, the photon dynamics in a single-mode cavity without losses on the mirrors is considered, which contains identical intracavity atoms coupled to the external vacuum electromagnetic field. For some atomic densities, the photons of the cavity mode are “locked” inside the cavity, thus exhibiting a new phenomenon of radiation trapping and non-Wiener dynamics.

  9. Review of Hydroelasticity Theories

    Chen, Xu-jun; Wu, You-sheng; Cui, Wei-cheng;

    2006-01-01

    Existing hydroelastic theories are reviewed. The theories are classified into different types: two-dimensional linear theory, two-dimensional nonlinear theory, three-dimensional linear theory and three-dimensional nonlinear theory. Applications to analysis of very large floating structures (VLFS)......) are reviewed and discussed in details. Special emphasis is placed on papers from China and Japan (in native languages) as these papers are not generally publicly known in the rest of the world....

  10. Entanglement quantification by neutron scattering

    Marty, Oliver; Plenio, Martin; Cramer, Marcus [Institut fuer Theoretische Physik, Universtitaet Ulm, Ulm (Germany); Epping, Michael; Kampermann, Hermann; Bruss, Dagmar [Institut fuer Theoretische Physik III, Heinrich-Heine Universitaet Duesseldorf, Duesseldorf (Germany)

    2013-07-01

    We present studies about the quantification of the entanglement contained in large samples of magnetic materials by structure factor measurements - a standard tool in analyzing condensed matter systems. We discuss experimentally relevant models (such as Heisenberg, Majumdar-Ghosh and XY models) in different geometries and with different spin numbers. For those, lower bounds to entanglement measures can be read off directly from the cross section obtained in neutron-scattering experiments.

  11. Risk Quantification and Evaluation Modelling

    Manmohan Singh; M.D. Jaybhaye; S. K. Basu

    2014-01-01

    In this paper authors have discussed risk quantification methods and evaluation of risks and decision parameter to be used for deciding on ranking of the critical items, for prioritization of condition monitoring based risk and reliability centered maintenance (CBRRCM). As time passes any equipment or any product degrades into lower effectiveness and the rate of failure or malfunctioning increases, thereby lowering the reliability. Thus with the passage of time or a number of active tests or ...

  12. An uncertainty inventory demonstration - a primary step in uncertainty quantification

    Langenbrunner, James R. [Los Alamos National Laboratory; Booker, Jane M [Los Alamos National Laboratory; Hemez, Francois M [Los Alamos National Laboratory; Salazar, Issac F [Los Alamos National Laboratory; Ross, Timothy J [UNM

    2009-01-01

    Tools, methods, and theories for assessing and quantifying uncertainties vary by application. Uncertainty quantification tasks have unique desiderata and circumstances. To realistically assess uncertainty requires the engineer/scientist to specify mathematical models, the physical phenomena of interest, and the theory or framework for assessments. For example, Probabilistic Risk Assessment (PRA) specifically identifies uncertainties using probability theory, and therefore, PRA's lack formal procedures for quantifying uncertainties that are not probabilistic. The Phenomena Identification and Ranking Technique (PIRT) proceeds by ranking phenomena using scoring criteria that results in linguistic descriptors, such as importance ranked with words, 'High/Medium/Low.' The use of words allows PIRT to be flexible, but the analysis may then be difficult to combine with other uncertainty theories. We propose that a necessary step for the development of a procedure or protocol for uncertainty quantification (UQ) is the application of an Uncertainty Inventory. An Uncertainty Inventory should be considered and performed in the earliest stages of UQ.

  13. Toward a theory of distinct types of "impulsive" behaviors: A meta-analysis of self-report and behavioral measures.

    Sharma, Leigh; Markon, Kristian E; Clark, Lee Anna

    2014-03-01

    Impulsivity is considered a personality trait affecting behavior in many life domains, from recreational activities to important decision making. When extreme, it is associated with mental health problems, such as substance use disorders, as well as with interpersonal and social difficulties, including juvenile delinquency and criminality. Yet, trait impulsivity may not be a unitary construct. We review commonly used self-report measures of personality trait impulsivity and related constructs (e.g., sensation seeking), plus the opposite pole, control or constraint. A meta-analytic principal-components factor analysis demonstrated that these scales comprise 3 distinct factors, each of which aligns with a broad, higher order personality factor-Neuroticism/Negative Emotionality, Disinhibition versus Constraint/Conscientiousness, and Extraversion/Positive Emotionality/Sensation Seeking. Moreover, Disinhibition versus Constraint/Conscientiousness comprise 2 correlated but distinct subfactors: Disinhibition versus Constraint and Conscientiousness/Will versus Resourcelessness. We also review laboratory tasks that purport to measure a construct similar to trait impulsivity. A meta-analytic principal-components factor analysis demonstrated that these tasks constitute 4 factors (Inattention, Inhibition, Impulsive Decision-Making, and Shifting). Although relations between these 2 measurement models are consistently low to very low, relations between both trait scales and laboratory behavioral tasks and daily-life impulsive behaviors are moderate. That is, both independently predict problematic daily-life impulsive behaviors, such as substance use, gambling, and delinquency; their joint use has incremental predictive power over the use of either type of measure alone and furthers our understanding of these important, problematic behaviors. Future use of confirmatory methods should help to ascertain with greater precision the number of and relations between impulsivity

  14. D-A-D-type narrow-bandgap small-molecule photovoltaic donors: pre-synthesis virtual screening using density functional theory.

    Gim, Yeongrok; Kim, Daekyeom; Kyeong, Minkyu; Byun, Seunghwan; Park, Yuri; Kwon, Sooncheol; Kim, Heejoo; Hong, Sukwon; Lansac, Yves; Jang, Yun Hee

    2016-06-01

    A new series of D-A-D-type small-molecule photovoltaic donors are designed and virtually screened before synthesis using time-dependent density functional theory calculations carefully validated against various polymeric and molecular donors. In this series of new design, benzodithiophene is kept as D to achieve the optimum highest-occupied molecular orbital energy level, while thienopyrroledione is initially chosen as A but later replaced by difluorinated benzodiathiazole or its selenide derivative to achieve the optimum band gap. The D-A-D core is end-capped by pyridone units which could not only enhance their self-assembly via hydrogen bonds but also play a role as an acceptor (A') to form an extended A'-D-A-D-A' small-molecule donor. PMID:27193426

  15. Magnetism in olivine-type LiCo(1-x)Fe(x)PO4 cathode materials: bridging theory and experiment.

    Singh, Vijay; Gershinsky, Yelena; Kosa, Monica; Dixit, Mudit; Zitoun, David; Major, Dan Thomas

    2015-12-14

    In the current paper, we present a non-aqueous sol-gel synthesis of olivine type LiCo1-xFexPO4 compounds (x = 0.00, 0.25, 0.50, 0.75, 1.00). The magnetic properties of the olivines are measured experimentally and calculated using first-principles theory. Specifically, the electronic and magnetic properties are studied in detail with standard density functional theory (DFT), as well as by including spin-orbit coupling (SOC), which couples the spin to the crystal structure. We find that the Co(2+) ions exhibit strong orbital moment in the pure LiCoPO4 system, which is partially quenched upon substitution of Co(2+) by Fe(2+). Interestingly, we also observe a non-negligible orbital moment on the Fe(2+) ion. We underscore that the inclusion of SOC in the calculations is essential to obtain qualitative agreement with the observed effective magnetic moments. Additionally, Wannier functions were used to understand the experimentally observed rising trend in the Néel temperature, which is directly related to the magnetic exchange interaction paths in the materials. We suggest that out of layer M-O-P-O-M magnetic interactions (J⊥) are present in the studied materials. The current findings shed light on important differences observed in the electrochemistry of the cathode material LiCoPO4 compared to the already mature olivine material LiFePO4. PMID:26548581

  16. 基于蒙特卡罗仿真法的研究型项目风险量化分析技术%Risk Quantification and Analysis for the Research-typed Projects Based on MCS Method

    高建伟

    2012-01-01

    With standardization, informatization, scientificness, and rationalization are more and more popular in the research project management, the risk management becomes more and more important. In risk management, risks in research project should be ordered by their importance, and the influence of risks on project schedule and cost should be also analyzed. A Monte Carlo Simulation (MCS)-based method for quantifying the risk in research project is developed in order to analyze the importance, schedule as well as the cost of the project. Firstly, the method for risk data capturing and processing is developed on basis of the triangle distribution. Secondly, the circle and cost models are developed separately on basis of Earliest Start Time (EST), Earliest Finish Time (EFT) as well as the Cost Breakdown Structure (CBS). Thirdly, the sampling algorithm and flow based on MCS is defined, the analysis method for probabilistic risk error is also proposed. Finally, a leveled risk analysis method is also developed on basis of the risk quantification; the total risk is divided into the risk of project and risks of subprojects. A method for computing completion probability of appointive deadline constraint-oriented project is discussed; in the meantime, the method for analyzing subproject progress-oriented risks is developed by using the index of key targets which are Key Probability (KP) and Key Importance (KI).%科学研究型项目的执行过程正逐步走向规范化、信息化、科学化和理性化,这就要求项目风险的评估和量化方式必须深入,不仅需要分析此类项目风险的重要度排序,还必须分析相关项目风险将会对进度和成本造成的影响,也就是对研究型项目进行风险量化管理.本文着重研究面向研究型项目的风险量化技术,提出了基于蒙特卡罗仿真法的项目定量风险量化技术,基于三角分布模型构建了相关风险数据的采集与处理方法,基于最早开始时间和最

  17. Two symmetric n-type interfaces SrTiO3/LaAlO3 in perovskite: Electronic properties from density functional theory

    Reshak, A. H.; Abu-Jafar, M. S.; Al-Douri, Y.

    2016-06-01

    The first principles study of the (001) two symmetric n-type interfaces between two insulating perovskites, the nonpolar SrTiO3 (STO), and the polar LaAlO3 (LAO) was performed. We have analyzed the formation of metallic interface states between the STO and LAO heterointerfaces by using the all-electron full-potential linearized augmented plane-wave approach based on the density functional theory, within the local density approximation, the Perdew-Burke-Ernzerhof generalized gradient approximation (PBE-GGA), and the Engel-Vosko GGA (EVGGA) formalism. It has been found that some bands cross the Fermi energy level (EF), forming a metallic nature of two symmetric n-type 6.5STO/1.5LAO interfaces with density of states at EF, N(EF) of about 3.56 (state/eV/unit cell), and bare electronic specific heat coefficient (γ) of about 0.62 mJ/(mol cell K2). The electronic band stature and the partial density of states in the vicinity of EF are mainly originated from Ti1,2,3,4-3dxy orbitals. These bands are responsible for the metallic behavior and the forming of the Fermi surface of the two symmetric n-type 6.5STO/1.5LAO interfaces. To obtain a clear map of the valence band electronic charge density distribution of the two symmetric n-type 6.5STO/1.5LAO interfaces, we have investigated the bond's nature and the interactions between the atoms. It reveals that the charge is attracted towards O atoms as it is clear that the O atoms are surrounded by uniform blue spheres which indicate the maximum charge accumulation.

  18. Quantification of bacterial invasion into adherent cells by flow cytometry

    Pils, Stefan; Schmitter, Tim; Neske, Florian; Hauck, Christof R.

    2006-01-01

    Quantification of invasive, intracellular bacteria is critical in many areas of cellular microbiology and immunology. We describe a novel and fast approach to determine invasion of bacterial pathogens in adherent cell types such as epithelial cells or fibroblasts based on flow cytometry. Using the CEACAM-mediated uptake of Opa-expressing Neisseria gonorrhoeae as a well-characterized model of bacterial invasion, we demonstrate that the flow cytometry-based method yields results comparable to a...

  19. Quantification of the Contribution of GLP-1 to Mediating Insulinotropic Effects of DPP-4 Inhibition With Vildagliptin in Healthy Subjects and Patients With Type 2 Diabetes Using Exendin [9-39] as a GLP-1 Receptor Antagonist.

    Nauck, Michael A; Kind, Joachim; Köthe, Lars D; Holst, Jens J; Deacon, Carolyn F; Broschag, Matthias; He, Yan Ling; Kjems, Lise; Foley, James

    2016-08-01

    We quantified the contribution of GLP-1 as a mediator of the therapeutic effects of dipeptidyl peptidase 4 (DPP-4) inhibition (vildagliptin) by using the GLP-1 receptor antagonist exendin [9-39] in patients with type 2 diabetes and in healthy subjects. Thirty-two patients with type 2 diabetes and 29 age- and weight-matched healthy control subjects were treated in randomized order with 100 mg once daily vildagliptin or placebo for 10 days. Meal tests were performed (days 9 and 10) without and with a high-dose intravenous infusion of exendin [9-39]. The main end point was the ratio of the areas under the curve (AUCs) of integrated insulin secretion rates (total AUCISR) and glucose (total AUCglucose) over 4 h after the meal. Vildagliptin treatment more than doubled responses of intact GLP-1 and glucose-dependent insulinotropic polypeptide and lowered glucose responses without changing AUCISR/AUCglucose in healthy subjects. Vildagliptin significantly increased this ratio by 10.5% in patients with type 2 diabetes, and exendin [9-39] reduced it (both P 39] was significantly smaller after vildagliptin treatment than after placebo treatment (P = 0.026) and was equivalent to 47 ± 5% of the increments due to vildagliptin. Thus, other mediators appear to contribute significantly to the therapeutic effects of DPP-4 inhibition. PMID:27207543

  20. Quantification of Information in a One-Way Plant-to-Animal Communication System

    Laurance R. Doyle

    2009-08-01

    Full Text Available In order to demonstrate possible broader applications of information theory to the quantification of non-human communication systems, we apply calculations of information entropy to a simple chemical communication from the cotton plant (Gossypium hirsutum to the wasp (Cardiochiles nigriceps studied by DeMoraes et al. The purpose of this chemical communication from cotton plants to wasps is presumed to be to allow the predatory wasp to more easily obtain the location of its preferred prey—one of two types of parasitic herbivores feeding on the cotton plants. Specification of the plant-eating herbivore feeding on it by the cotton plants allows preferential attraction of the wasps to those individual plants. We interpret the emission of nine chemicals by the plants as individual signal differences, (depending on the herbivore type, to be detected by the wasps as constituting a nine-signal one-way communication system across kingdoms (from the kingdom Plantae to the kingdom Animalia. We use fractional differences in the chemical abundances, (emitted as a result of the two herbivore types, to calculate the Shannon information entropic measures (marginal, joint, and mutual entropies, as well as the ambiguity, etc. of the transmitted message. We then compare these results with the subsequent behavior of the wasps, (calculating the equivocation in the message reception, for possible insights into the history and actual working of this one-way communication system.

  1. Aerobic physical activity and resistance training: an application of the theory of planned behavior among adults with type 2 diabetes in a random, national sample of Canadians

    Karunamuni Nandini

    2008-12-01

    Full Text Available Abstract Background Aerobic physical activity (PA and resistance training are paramount in the treatment and management of type 2 diabetes (T2D, but few studies have examined the determinants of both types of exercise in the same sample. Objective The primary purpose was to investigate the utility of the Theory of Planned Behavior (TPB in explaining aerobic PA and resistance training in a population sample of T2D adults. Methods A total of 244 individuals were recruited through a random national sample which was created by generating a random list of household phone numbers. The list was proportionate to the actual number of household telephone numbers for each Canadian province (with the exception of Quebec. These individuals completed self-report TPB constructs of attitude, subjective norm, perceived behavioral control and intention, and a 3-month follow-up that assessed aerobic PA and resistance training. Results TPB explained 10% and 8% of the variance respectively for aerobic PA and resistance training; and accounted for 39% and 45% of the variance respectively for aerobic PA and resistance training intentions. Conclusion These results may guide the development of appropriate PA interventions for aerobic PA and resistance training based on the TPB.

  2. Predicting Noninsulin Antidiabetic Drug Adherence Using a Theoretical Framework Based on the Theory of Planned Behavior in Adults With Type 2 Diabetes

    Zomahoun, Hervé Tchala Vignon; Moisan, Jocelyne; Lauzier, Sophie; Guillaumie, Laurence; Grégoire, Jean-Pierre; Guénette, Line

    2016-01-01

    Abstract Understanding the process behind noninsulin antidiabetic drug (NIAD) nonadherence is necessary for designing effective interventions to resolve this problem. This study aimed to explore the ability of the theory of planned behavior (TPB), which is known as a good predictor of behaviors, to predict the future NIAD adherence in adults with type 2 diabetes. We conducted a prospective study of adults with type 2 diabetes. They completed a questionnaire on TPB variables and external variables. Linear regression was used to explore the TPB's ability to predict future NIAD adherence, which was prospectively measured as the proportion of days covered by at least 1 NIAD using pharmacy claims data. The interaction between past NIAD adherence and intention was tested. The sample included 340 people. There was an interaction between past NIAD adherence and intention to adhere to the NIAD (P = 0.032). Intention did not predict future NIAD adherence in the past adherers and nonadherers groups, but its association measure was high among past nonadherers (β = 5.686, 95% confidence interval [CI] −10.174, 21.546). In contrast, intention was mainly predicted by perceived behavioral control both in the past adherers (β = 0.900, 95% CI 0.796, 1.004) and nonadherers groups (β = 0.760, 95% CI 0.555, 0.966). The present study suggests that TPB is a good tool to predict intention to adhere and future NIAD adherence. However, there was a gap between intention to adhere and actual adherence to the NIAD, which is partly explained by the past adherence level in adults with type 2 diabetes. PMID:27082543

  3. Predicting Noninsulin Antidiabetic Drug Adherence Using a Theoretical Framework Based on the Theory of Planned Behavior in Adults With Type 2 Diabetes: A Prospective Study.

    Zomahoun, Hervé Tchala Vignon; Moisan, Jocelyne; Lauzier, Sophie; Guillaumie, Laurence; Grégoire, Jean-Pierre; Guénette, Line

    2016-04-01

    Understanding the process behind noninsulin antidiabetic drug (NIAD) nonadherence is necessary for designing effective interventions to resolve this problem. This study aimed to explore the ability of the theory of planned behavior (TPB), which is known as a good predictor of behaviors, to predict the future NIAD adherence in adults with type 2 diabetes. We conducted a prospective study of adults with type 2 diabetes. They completed a questionnaire on TPB variables and external variables. Linear regression was used to explore the TPB's ability to predict future NIAD adherence, which was prospectively measured as the proportion of days covered by at least 1 NIAD using pharmacy claims data. The interaction between past NIAD adherence and intention was tested. The sample included 340 people. There was an interaction between past NIAD adherence and intention to adhere to the NIAD (P = 0.032). Intention did not predict future NIAD adherence in the past adherers and nonadherers groups, but its association measure was high among past nonadherers (β = 5.686, 95% confidence interval [CI] -10.174, 21.546). In contrast, intention was mainly predicted by perceived behavioral control both in the past adherers (β = 0.900, 95% CI 0.796, 1.004) and nonadherers groups (β = 0.760, 95% CI 0.555, 0.966). The present study suggests that TPB is a good tool to predict intention to adhere and future NIAD adherence. However, there was a gap between intention to adhere and actual adherence to the NIAD, which is partly explained by the past adherence level in adults with type 2 diabetes. PMID:27082543

  4. MODELS OF CAPITAL COSTS QUANTIFICATION

    Tomáš KLIEŠTIK; Katarína VALÁŠKOVÁ

    2013-01-01

    The present contribution deals with the quantification of capital costs. The contribution is written on a theoretical basis. The costs will be particularly quantified in financing only by equity and only by debt capital and particularly in the so-called mixed financing in which weighted average costs of capital will be quantified. The cost of capital can be seen from three different perspectives: in the assets part of a company, in the liability part of a company and in the part of potential ...

  5. An EPGPT-based approach for uncertainty quantification

    Wang, C.; Abdel-Khalik, H. S. [Dept. of Nuclear Engineering, North Caroline State Univ., Raleigh, NC 27695 (United States)

    2012-07-01

    Generalized Perturbation Theory (GPT) has been widely used by many scientific disciplines to perform sensitivity analysis and uncertainty quantification. This manuscript employs recent developments in GPT theory, collectively referred to as Exact-to-Precision Generalized Perturbation Theory (EPGPT), to enable uncertainty quantification for computationally challenging models, e.g. nonlinear models associated with many input parameters and many output responses and with general non-Gaussian parameters distributions. The core difference between EPGPT and existing GPT is in the way the problem is formulated. GPT formulates an adjoint problem that is dependent on the response of interest. It tries to capture via the adjoint solution the relationship between the response of interest and the constraints on the state variations. EPGPT recasts the problem in terms of a smaller set of what is referred to as the 'active' responses which are solely dependent on the physics model and the boundary and initial conditions rather than on the responses of interest. The objective of this work is to apply an EPGPT methodology to propagate cross-sections variations in typical reactor design calculations. The goal is to illustrate its use and the associated impact for situations where the typical Gaussian assumption for parameters uncertainties is not valid and when nonlinear behavior must be considered. To allow this demonstration, exaggerated variations will be employed to stimulate nonlinear behavior in simple prototypical neutronics models. (authors)

  6. An EPGPT-based approach for uncertainty quantification

    Generalized Perturbation Theory (GPT) has been widely used by many scientific disciplines to perform sensitivity analysis and uncertainty quantification. This manuscript employs recent developments in GPT theory, collectively referred to as Exact-to-Precision Generalized Perturbation Theory (EPGPT), to enable uncertainty quantification for computationally challenging models, e.g. nonlinear models associated with many input parameters and many output responses and with general non-Gaussian parameters distributions. The core difference between EPGPT and existing GPT is in the way the problem is formulated. GPT formulates an adjoint problem that is dependent on the response of interest. It tries to capture via the adjoint solution the relationship between the response of interest and the constraints on the state variations. EPGPT recasts the problem in terms of a smaller set of what is referred to as the 'active' responses which are solely dependent on the physics model and the boundary and initial conditions rather than on the responses of interest. The objective of this work is to apply an EPGPT methodology to propagate cross-sections variations in typical reactor design calculations. The goal is to illustrate its use and the associated impact for situations where the typical Gaussian assumption for parameters uncertainties is not valid and when nonlinear behavior must be considered. To allow this demonstration, exaggerated variations will be employed to stimulate nonlinear behavior in simple prototypical neutronics models. (authors)

  7. Quantification of wastewater sludge dewatering.

    Skinner, Samuel J; Studer, Lindsay J; Dixon, David R; Hillis, Peter; Rees, Catherine A; Wall, Rachael C; Cavalida, Raul G; Usher, Shane P; Stickland, Anthony D; Scales, Peter J

    2015-10-01

    Quantification and comparison of the dewatering characteristics of fifteen sewage sludges from a range of digestion scenarios are described. The method proposed uses laboratory dewatering measurements and integrity analysis of the extracted material properties. These properties were used as inputs into a model of filtration, the output of which provides the dewatering comparison. This method is shown to be necessary for quantification and comparison of dewaterability as the permeability and compressibility of the sludges varies by up to ten orders of magnitude in the range of solids concentration of interest to industry. This causes a high sensitivity of the dewaterability comparison to the starting concentration of laboratory tests, thus simple dewaterability comparison based on parameters such as the specific resistance to filtration is difficult. The new approach is demonstrated to be robust relative to traditional methods such as specific resistance to filtration analysis and has an in-built integrity check. Comparison of the quantified dewaterability of the fifteen sludges to the relative volatile solids content showed a very strong correlation in the volatile solids range from 40 to 80%. The data indicate that the volatile solids parameter is a strong indicator of the dewatering behaviour of sewage sludges. PMID:26003332

  8. Lax-Phillips scattering theory with perturbations of the type: V(x)=(φ(x))/|x|β, where β=2-(n)/s, φ is an element of Ls(Rn), s > 2 and s ≥ (n)/2

    A scattering theory for the wave equation with compactly supported perturbations was developed by Lax-Phillips in 1967. Using Enss approach, Phillips developed a Lax-Phillips scattering theory with short range perturbations of the type: V(x)=o((1)/|x|β), β > 2. In this paper we develop a scattering theory for more general perturbations, i.e. for V(x)=(φ(x))/|x|β, where β=2-(n)/s, φ is an element of Ls(Rn), s > 2 and s ≥ (n)/2. Refs

  9. Detection and Quantification of Neurotransmitters in Dialysates

    Zapata, Agustin; Chefer, Vladimir I.; Shippenberg, Toni S.; Denoroy, Luc

    2009-01-01

    Sensitive analytical methods are needed for the separation and quantification of neurotransmitters obtained in microdialysate studies. This unit describes methods that permit quantification of nanomolar concentrations of monoamines and their metabolites (high-pressure liquid chromatography electrochemical detection), acetylcholine (HPLC-coupled to an enzyme reactor), and amino acids (HPLC-fluorescence detection; capillary electrophoresis with laser-induced fluorescence detection).

  10. Thermal expansion of mullite-type Bi2Al4O9: A study by X-ray diffraction, vibrational spectroscopy and density functional theory

    Polycrystalline Bi2Al4O9 powder samples were synthesized using the glycerine method. Single crystals were produced from the powder product in a Bi2O3 melt. The lattice thermal expansion of the mullite-type compound was studied using X-ray diffraction, Raman spectroscopy and density functional theory (DFT). The metric parameters were modeled using Grüneisen approximation for the zero pressure equation of state, where the temperature-dependent vibrational internal energy was calculated from the Debye characteristic frequency. Both the first-order and second-order Grüneisen approximations were applied for modeling the volumetric expansion, and the second-order approach provided physically meaningful axial parameters. The phonon density of states as well as phonon dispersion guided to set the characteristic frequency for simulation. The experimental infrared and Raman phonon bands were compared with those calculate from the DFT calculations. Selective Raman modes were analyzed for the thermal anharmonic behaviors using simplified Klemens model. The respective mode Grüneisen parameters were calculated from the pressure-dependent Raman spectra. - Graphical abstract: Crystal structure of mullite-type Bi2Al4O9 showing the edge-sharing AlO6 octahedra running parallel to the c-axis. - Highlights: • Thermal expansion of Bi2Al4O9 was studied using XRD, FTIR, Raman and DFT. • Metric parameters were modeled using Grüneisen approximation. • Phonon DOS and phonon dispersion helped to set the Debye frequency. • Mode Grüneisen parameters were calculated from the pressure-dependent Raman spectra. • Anharmonicity was analyzed for some selective Raman modes

  11. The thermodynamic, electronic and elastic properties of the early-transition-metal diborides with AlB2-type structure: A density functional theory study

    Highlights: • The thermodynamic characters of TMB2 have been firstly studied using the QHA method. • WB2 and TaB2 are good candidates for the structural application at high temperature. • Most of the early-transition-metal diborides cannot be easily machined. • The correlations between elastic constants and VECs of TMB2 have been discussed. - Abstract: The thermodynamic, electronic and elastic properties of a class of early-transition-metal diborides (TMB2, TM = Sc, Ti, V, Cr, Y, Zr, Nb, Mo, Hf, Ta, W) with AlB2-type structure have been investigated using the quasi-harmonic Debye model and the ab initio calculation based on the density functional theory, respectively. According to the characters of temperature dependent bulk modulus and coefficient of thermal expansion, the TMB2 compounds can be divided into three groups. The results also indicate that 4d- and 5d-TMB2 compounds are good high-temperature structural materials. The five independent stiffness coefficients, bulk and shear moduli of the diborides are obtained and well agreement with the available experimental and theoretical data. The correlations between elastic properties and electronic structure are discussed in detail. Due to the high values of hardness, the VIB-transition-metal diborides with relatively high B/G and B/C44 ratios are still difficult to machine with usual methods

  12. ["A Little Bit of Switzerland, a Little Bit of Kosovo". Swiss Immigrants from Former Yugoslavia with Type 2 Diabetes. A Qualitative Study' in Analogy to Grounded Theory].

    Wenger, A; Mischke, C

    2015-10-01

    Type 2 diabetes is on the increase among the Swiss immigrants. The cultural background of patients presents new linguistic and sociocultural barriers and gains in importance for health care. In order to develop patient-centred care, it is necessary to focus on different sociocultural aspects in everyday life and experiences of immigrants from the former republics of Yugoslavia with diabetes who have rarely been studied in Switzerland. Based on these insights the needs for counselling can be identified and nursing interventions can be designed accordingly. Using the Grounded Theory approach, 5 interviews were analysed according to the Corbin and Strauss coding paradigm. The central phenomenon found is the experience to live in 2 different cultures. The complexity arises from the tension living in 2 cultural backgrounds at the same time. It turns out that in the country of origin the immigrants adjust their disease management. The changing daily rhythm and the more traditional role model affect aspects of their disease management such as diet and/or drug therapy. The different strategies impact the person's roles, emotions, their everyday lives and their families. It provides an insight into the perspective of Swiss immigrants from the former republics of Yugoslavia suffering from diabetes. Many questions are still unanswered and further research will be required. PMID:26270044

  13. Rate theory modeling of defect evolution under cascade damage conditions: the influence of vacancy-type cascade remnants and application to the defect production characterization by microstructural analysis

    Recent computational and experimental studies have confirmed that high energy cascades produce clustered defects of both vacancy- and interstitial-types as well as isolated point defects. However, the production probability, configuration, stability and other characteristics of the cascade clusters are not well understood in spite of the fact that clustered defect production would substantially affect the irradiation-induced microstructures and the consequent property changes in a certain range of temperatures and displacement rates. In this work, a model of point defect and cluster evolution in irradiated materials under cascade damage conditions was developed by combining the conventional reaction rate theory and the results from the latest molecular dynamics simulation studies. This paper provides a description of the model and a model-based fundamental investigation of the influence of configuration, production efficiency and the initial size distribution of cascade-produced vacancy clusters. In addition, using the model, issues on characterizing cascade-induced defect production by microstructural analysis will be discussed. In particular, the determination of cascade vacancy cluster configuration, surviving defect production efficiency and cascade-interaction volume is attempted by analyzing the temperature dependence of swelling rate and loop growth rate in austenitic steels and model alloys. (author)

  14. Secular Dynamics of S-type Planetary Orbits in Binary Star Systems: Applicability Domains of First- and Second-Order Theories

    Andrade-Ines, Eduardo; Michtchenko, Tatiana; Robutel, Philippe

    2015-01-01

    We analyse the secular dynamics of planets on S-type coplanar orbits in tight binary systems, based on first- and second-order analytical models, and compare their predictions with full N-body simulations. The perturbation parameter adopted for the development of these models depends on the masses of the stars and on the semimajor axis ratio between the planet and the binary. We show that each model has both advantages and limitations. While the first-order analytical model is algebraically simple and easy to implement, it is only applicable in regions of the parameter space where the perturbations are sufficiently small. The second-order model, although more complex, has a larger range of validity and must be taken into account for dynamical studies of some real exoplanetary systems such as $\\gamma$-Cephei and HD 41004A. However, in some extreme cases, neither of these analytical models yields quantitatively correct results, requiring either higher-order theories or direct numerical simulations. Finally, we ...

  15. Experimento para quantificar a eficiência de aspersão de líquidos: aplicação em distribuidores espinha de peixe Liquid aspersion efficiency quantification experiment: application in ladder-type distributors

    Marlene Silva de Moraes

    2008-03-01

    Full Text Available O presente texto descreve um equipamento na escala-piloto e um método simples para comparar a eficiência de distribuidores de líquido. A técnica consiste basicamente em analisar a massa do líquido coletado em 21 tubos verticais de 52mm de diâmetro interno e 800 mm de comprimento dispostos em arranjo quadrático colocados abaixo do distribuidor. Uma manta acrílica que não dispersa o líquido com 50 mm de espessura foi fixada entre o distribuidor e o banco de tubos para evitar respingos. Como exemplo de aplicação foram realizados ensaios com nove distribuidores do tipo espinha de peixe de 4 tubos paralelos cada, para uma coluna com 400 mm de diâmetro. Variaram-se o número (n de furos (95, 127 e 159 furos/m², o diâmetro (d dos furos (2, 3 e 4 mm e as vazões (q de (1,2; 1,4 e 1,6m³/h. A melhor eficiência de espalhamento pelo menor desvio-padrão foi obtida com n de 159, d de 2 e q de 1,4 indicando as limitações de regras práticas de projeto. A pressão (p, na entrada do distribuidor, para essa condição, foi de apenas 51000 Pa (0,51 kgf/cm² e a velocidade média (v em cada orifício foi de 6,3 m/s.This paper describes a device developed on the pilot scale and a simple approach to compare liquid distributor efficiencies. The technique consists basically of analyzing the mass of the liquid collected in 21 vertical pipes measuring 52 mm in internal diameter and 800 mm in length placed in a quadratic arrangement and positioned below the distributor. A 50 mm thick acrylic blanket that does not disperse liquids was placed between the distributor and the pipe bank to avoid splashes. Assays were carried out with ladder-type distributors equipped with 4 parallel pipes each for a column measuring 400 mm in diameter as an example of the application. The number (n of orifices (95, 127, and 159 orifices/m², orifice diameter (d (2, 3, and 4 mm and the flowrate (q (1.2; 1.4; and 1.6 m3/h were varied. The best spread efficiency, which

  16. Visualization and quantification of dopamine

    Spiperone is a potent antagonist of dopamine D2 receptors in the brain. 3-N-[11C] methylspiperone (11C-NMSP), a spiperone derivative, was synthesized by N-alkylation of spiperone with [11C] methyliodide for the visualization and quantification of dopamine receptors in the brain using PET. Age related decrease of 11C-NMSP binding to the striatum was studied in healthy normal volunteers and the binding capacity was also examined in patients with Parkinson's disease and striatonigral degeneration (SND). After intravenous injection of 11C-NMSP, 5 sequential 2 min scan followed by 16 sequential 5 min scan were performed using a PET system. Region of interests to the striatum, cerebral cortex and cerebellum were outlined in the brain image and were plotted against time. The radioactivity in the striatum, in which much D2 binding site exists, was the highest among the brain and gradually increased with time. On the other hand, that in the cerebellar cortex, in which only non-specific binding site exists, peaked within 10 min, followed by rapid decrease. The ratios between striatum and cerebellum, which correlate with specific binding of 11C-NMSP, increased with time and had a linear relationship against time. Quantification of specific binding was evaluated by taking receptor-ligand association rate constant 'K3' in 3 conpartment model. The constant K3 was evaluated from the slope of the striatum to cerebellum ratio vesus an equivalent time which was calculated by the radioactivity in the cerebellulm. Decrease of K3 value with increase of age was observed. The values in Parkinson's disease were almost the same or slightly higher than those in age-matched control, however, a significant decrease compated to the normal value was observed in SND. The possible explanations for unchange or slight increase in Parkinson's disease and the decrease in SND were discussed. (author)

  17. Using psychological theory to understand the clinical management of type 2 diabetes in Primary Care: a comparison across two European countries

    Johnston Marie

    2009-08-01

    Full Text Available Abstract Background Long term management of patients with Type 2 diabetes is well established within Primary Care. However, despite extensive efforts to implement high quality care both service provision and patient health outcomes remain sub-optimal. Several recent studies suggest that psychological theories about individuals' behaviour can provide a valuable framework for understanding generalisable factors underlying health professionals' clinical behaviour. In the context of the team management of chronic disease such as diabetes, however, the application of such models is less well established. The aim of this study was to identify motivational factors underlying health professional teams' clinical management of diabetes using a psychological model of human behaviour. Methods A predictive questionnaire based on the Theory of Planned Behaviour (TPB investigated health professionals' (HPs' cognitions (e.g., beliefs, attitudes and intentions about the provision of two aspects of care for patients with diabetes: prescribing statins and inspecting feet. General practitioners and practice nurses in England and the Netherlands completed parallel questionnaires, cross-validated for equivalence in English and Dutch. Behavioural data were practice-level patient-reported rates of foot examination and use of statin medication. Relationships between the cognitive antecedents of behaviour proposed by the TPB and healthcare teams' clinical behaviour were explored using multiple regression. Results In both countries, attitude and subjective norm were important predictors of health professionals' intention to inspect feet (Attitude: beta = .40; Subjective Norm: beta = .28; Adjusted R2 = .34, p 2 = .40, p Conclusion Using the TPB, we identified modifiable factors underlying health professionals' intentions to perform two clinical behaviours, providing a rationale for the development of targeted interventions. However, we did not observe a relationship

  18. Design Theory in Information Systems

    Shirley Gregor

    2002-01-01

    The aim of this paper is to explore an important category of information systems knowledge that is termed “design theory”. This knowledge is distinguished as the fifth of five types of theory: (i) theory for analysing and describing, (ii) theory for understanding, (iii) theory for predicting, (iv) theory for explaining and predicting, and (v) theory for design and action. Examples of design theory in information systems are provided, with associated research methods. The limited understanding...

  19. Development of Quantification Method for Bioluminescence Imaging

    Optical molecular luminescence imaging is widely used for detection and imaging of bio-photons emitted by luminescent luciferase activation. The measured photons in this method provide the degree of molecular alteration or cell numbers with the advantage of high signal-to-noise ratio. To extract useful information from the measured results, the analysis based on a proper quantification method is necessary. In this research, we propose a quantification method presenting linear response of measured light signal to measurement time. We detected the luminescence signal by using lab-made optical imaging equipment of animal light imaging system (ALIS) and different two kinds of light sources. One is three bacterial light-emitting sources containing different number of bacteria. The other is three different non-bacterial light sources emitting very weak light. By using the concept of the candela and the flux, we could derive simplified linear quantification formula. After experimentally measuring light intensity, the data was processed with the proposed quantification function. We could obtain linear response of photon counts to measurement time by applying the pre-determined quantification function. The ratio of the re-calculated photon counts and measurement time present a constant value although different light source was applied. The quantification function for linear response could be applicable to the standard quantification process. The proposed method could be used for the exact quantitative analysis in various light imaging equipment with presenting linear response behavior of constant light emitting sources to measurement time

  20. Supersymmetric Gauge Theories from String Theory

    Metzger, Steffen

    2005-01-01

    The subject of this thesis are various ways to construct four-dimensional quantum field theories from string theory. In a first part we study the generation of a supersymmetric Yang-Mills theory, coupled to an adjoint chiral superfield, from type IIB string theory on non-compact Calabi-Yau manifolds, with D-branes wrapping certain subcycles. Properties of the gauge theory are then mapped to the geometric structure of the Calabi-Yau space. In particular, the low energy effective superpotential...

  1. A shear deformable theory of laminated composite shallow shell-type panels and their response analysis. I - Free vibration and buckling

    Librescu, L.; Khdeir, A. A.; Frederick, D.

    1989-01-01

    This paper deals with the substantiation of a shear deformable theory of cross-ply laminated composite shallow shells. While the developed theory preserves all the advantages of the first order transverse shear deformation theory it succeeds in eliminating some of its basic shortcomings. The theory is further employed in the analysis of the eigenvibration and static buckling problems of doubly curved shallow panels. In this context, the state space concept is used in conjunction with the Levy method, allowing one to analyze these problems in a unified manner, for a variety of boundary conditions. Numerical results are presented and some pertinent conclusions are formulated.

  2. Dempster-Shafer theory and connections to information theory

    Peri, Joseph S. J.

    2013-05-01

    The Dempster-Shafer theory is founded on probability theory. The entire machinery of probability theory, and that of measure theory, is at one's disposal for the understanding and the extension of the Dempster-Shafer theory. It is well known that information theory is also founded on probability theory. Claude Shannon developed, in the 1940's, the basic concepts of the theory and demonstrated their utility in communications and coding. Shannonian information theory is not, however, the only type of information theory. In the 1960's and 1970's, further developments in this field were made by French and Italian mathematicians. They developed information theory axiomatically, and discovered not only the Wiener- Shannon composition law, but also the hyperbolic law and the Inf-law. The objective of this paper is to demonstrate the mathematical connections between the Dempster Shafer theory and the various types of information theory. A simple engineering example will be used to demonstrate the utility of the concepts.

  3. Topological Domain Theory

    Battenfeld, Ingo

    2008-01-01

    This thesis presents Topological Domain Theory as a powerful and flexible framework for denotational semantics. Topological Domain Theory models a wide range of type constructions and can interpret many computational features. Furthermore, it has close connections to established frameworks for denotational semantics, as well as to well-studied mathematical theories, such as topology and computable analysis.

  4. Superspace conformal field theory

    Quella, Thomas [Koeln Univ. (Germany). Inst. fuer Theoretische Physik; Schomerus, Volker [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2013-07-15

    Conformal sigma models and WZW models on coset superspaces provide important examples of logarithmic conformal field theories. They possess many applications to problems in string and condensed matter theory. We review recent results and developments, including the general construction of WZW models on type I supergroups, the classification of conformal sigma models and their embedding into string theory.

  5. Superspace conformal field theory

    Conformal sigma models and WZW models on coset superspaces provide important examples of logarithmic conformal field theories. They possess many applications to problems in string and condensed matter theory. We review recent results and developments, including the general construction of WZW models on type I supergroups, the classification of conformal sigma models and their embedding into string theory.

  6. Legionella spp. isolation and quantification from greywater.

    Rodríguez-Martínez, Sara; Blanky, Marina; Friedler, Eran; Halpern, Malka

    2015-01-01

    Legionella, an opportunistic human pathogen whose natural environment is water, is transmitted to humans through inhalation of contaminated aerosols. Legionella has been isolated from a high diversity of water types. Due its importance as a pathogen, two ISO protocols have been developed for its monitoring. However, these two protocols are not suitable for analyzing Legionella in greywater (GW). GW is domestic wastewater excluding the inputs from toilets and kitchen. It can serve as an alternative water source, mainly for toilet flushing and garden irrigation; both producing aerosols that can cause a risk for Legionella infection. Hence, before reuse, GW has to be treated and its quality needs to be monitored. The difficulty of Legionella isolation from GW strives in the very high load of contaminant bacteria. Here we describe a modification of the ISO protocol 11731:1998 that enables the isolation and quantification of Legionella from GW samples. The following modifications were made:•To enable isolation of Legionella from greywater, a pre-filtration step that removes coarse matter is recommended.•Legionella can be isolated after a combined acid-thermic treatment that eliminates the high load of contaminant bacteria in the sample. PMID:26740925

  7. Legionella spp. isolation and quantification from greywater

    Rodríguez-Martínez, Sara; Blanky, Marina; Friedler, Eran; Halpern, Malka

    2015-01-01

    Legionella, an opportunistic human pathogen whose natural environment is water, is transmitted to humans through inhalation of contaminated aerosols. Legionella has been isolated from a high diversity of water types. Due its importance as a pathogen, two ISO protocols have been developed for its monitoring. However, these two protocols are not suitable for analyzing Legionella in greywater (GW). GW is domestic wastewater excluding the inputs from toilets and kitchen. It can serve as an alternative water source, mainly for toilet flushing and garden irrigation; both producing aerosols that can cause a risk for Legionella infection. Hence, before reuse, GW has to be treated and its quality needs to be monitored. The difficulty of Legionella isolation from GW strives in the very high load of contaminant bacteria. Here we describe a modification of the ISO protocol 11731:1998 that enables the isolation and quantification of Legionella from GW samples. The following modifications were made:•To enable isolation of Legionella from greywater, a pre-filtration step that removes coarse matter is recommended.•Legionella can be isolated after a combined acid-thermic treatment that eliminates the high load of contaminant bacteria in the sample. PMID:26740925

  8. Evaluation of vehicle damage involved in road crashes based on quantificated model

    FAN Yan-hui; XU Hong-guo; JIANG Hua-ping

    2008-01-01

    Based on economics theory, social value loss caused by vehicle involved in crashes as well as various factors influencing on it were analyzed, the corresponding micro-econometrics model was theoretically given. Moreover, the practicability of the model,the veracity and rationality of quantification were analyzed. Based on probability theory and mathematical statistical theory, macro approach to evaluating vehicle damage in crashes was presented, and the corresponding macro-econometrics model was constructed. In addition, the macro-econometrics model was utilized to assess economic loss from statistical data of vehicle damaged in crashes, which has shown that the model can meet the demand of quantification analysis of vehicle damage, and be applied to the evaluation of economic loss caused by crashes. The results in this paper will be of practical significance for scientific, comprehensive and rational evaluating socio-economic loss caused by road crashes.

  9. Alberta Diabetes and Physical Activity Trial (ADAPT: A randomized theory-based efficacy trial for adults with type 2 diabetes - rationale, design, recruitment, evaluation, and dissemination

    Birkett Nicholas

    2010-01-01

    Full Text Available Abstract Background The primary aim of this study was to compare the efficacy of three physical activity (PA behavioural intervention strategies in a sample of adults with type 2 diabetes. Method/Design Participants (N = 287 were randomly assigned to one of three groups consisting of the following intervention strategies: (1 standard printed PA educational materials provided by the Canadian Diabetes Association [i.e., Group 1/control group]; (2 standard printed PA educational materials as in Group 1, pedometers, a log book and printed PA information matched to individuals' PA stage of readiness provided every 3 months (i.e., Group 2; and (3 PA telephone counseling protocol matched to PA stage of readiness and tailored to personal characteristics, in addition to the materials provided in Groups 1 and 2 (i.e., Group 3. PA behaviour measured by the Godin Leisure Time Exercise Questionnaire and related social-cognitive measures were assessed at baseline, 3, 6, 9, 12 and 18-months (i.e., 6-month follow-up. Clinical (biomarkers and health-related quality of life assessments were conducted at baseline, 12-months, and 18-months. Linear Mixed Model (LMM analyses will be used to examine time-dependent changes from baseline across study time points for Groups 2 and 3 relative to Group 1. Discussion ADAPT will determine whether tailored but low-cost interventions can lead to sustainable increases in PA behaviours. The results may have implications for practitioners in designing and implementing theory-based physical activity promotion programs for this population. Clinical Trials Registration ClinicalTrials.gov identifier: NCT00221234

  10. Matrix Theory on Non-Orientable Surfaces

    Zwart, Gysbert

    1997-01-01

    We construct the Matrix theory descriptions of M-theory on the Mobius strip and the Klein bottle. In a limit, these provide the matrix string theories for the CHL string and an orbifold of type IIA string theory.

  11. Uncertainty Quantification in Aerodynamics Simulations Project

    National Aeronautics and Space Administration — The objective of the proposed work (Phases I and II) is to develop uncertainty quantification methodologies and software suitable for use in CFD simulations of...

  12. Quantification of nanowire uptake by live cells

    Margineanu, Michael B.

    2015-05-01

    Nanostructures fabricated by different methods have become increasingly important for various applications at the cellular level. In order to understand how these nanostructures “behave” and for studying their internalization kinetics, several attempts have been made at tagging and investigating their interaction with living cells. In this study, magnetic iron nanowires with an iron oxide layer are coated with (3-Aminopropyl)triethoxysilane (APTES), and subsequently labeled with a fluorogenic pH-dependent dye pHrodo™ Red, covalently bound to the aminosilane surface. Time-lapse live imaging of human colon carcinoma HCT 116 cells interacting with the labeled iron nanowires is performed for 24 hours. As the pHrodo™ Red conjugated nanowires are non-fluorescent outside the cells but fluoresce brightly inside, internalized nanowires are distinguished from non-internalized ones and their behavior inside the cells can be tracked for the respective time length. A machine learning-based computational framework dedicated to automatic analysis of live cell imaging data, Cell Cognition, is adapted and used to classify cells with internalized and non-internalized nanowires and subsequently determine the uptake percentage by cells at different time points. An uptake of 85 % by HCT 116 cells is observed after 24 hours incubation at NW-to-cell ratios of 200. While the approach of using pHrodo™ Red for internalization studies is not novel in the literature, this study reports for the first time the utilization of a machine-learning based time-resolved automatic analysis pipeline for quantification of nanowire uptake by cells. This pipeline has also been used for comparison studies with nickel nanowires coated with APTES and labeled with pHrodo™ Red, and another cell line derived from the cervix carcinoma, HeLa. It has thus the potential to be used for studying the interaction of different types of nanostructures with potentially any live cell types.

  13. Antibody-free PRISM-SRM for multiplexed protein quantification: Is this the new competition for immunoassays in bioanalysis?

    Shi, Tujin; Qian, Weijun

    2013-02-01

    Highly sensitive technologies for multiplexed quantification of a large number of candidate proteins will play an increasingly important role in clinical biomarker discovery, systems biology, and general biomedical research. Herein we introduce the new PRISM-SRM technology, which represents a highly sensitive multiplexed quantification technology capable of simultaneous quantification of many low-abundance proteins without the need of affinity reagents. The versatility of antibody-free PRISM-SRM for quantifying various types of targets including protein isoforms, protein modifications, metabolites, and others, thus offering new competition with immunoassays.

  14. Risk Quantification and Evaluation Modelling

    Manmohan Singh

    2014-07-01

    Full Text Available In this paper authors have discussed risk quantification methods and evaluation of risks and decision parameter to be used for deciding on ranking of the critical items, for prioritization of condition monitoring based risk and reliability centered maintenance (CBRRCM. As time passes any equipment or any product degrades into lower effectiveness and the rate of failure or malfunctioning increases, thereby lowering the reliability. Thus with the passage of time or a number of active tests or periods of work, the reliability of the product or the system, may fall down to a low value known as a threshold value, below which the reliability should not be allowed to dip. Hence, it is necessary to fix up the normal basis for determining the appropriate points in the product life cycle where predictive preventive maintenance may be applied in the programme so that the reliability (the probability of successful functioning can be enhanced, preferably to its original value, by reducing the failure rate and increasing the mean time between failure. It is very important for defence application where reliability is a prime work. An attempt is made to develop mathematical model for risk assessment and ranking them. Based on likeliness coefficient β1 and risk coefficient β2 ranking of the sub-systems can be modelled and used for CBRRCM.Defence Science Journal, Vol. 64, No. 4, July 2014, pp. 378-384, DOI:http://dx.doi.org/10.14429/dsj.64.6366 

  15. Lung involvement quantification in chest radiographs

    Tuberculosis (TB) caused by Mycobacterium tuberculosis, is an infectious disease which remains a global health problem. The chest radiography is the commonly method employed to assess the TB's evolution. The methods for quantification of abnormalities of chest are usually performed on CT scans (CT). This quantification is important to assess the TB evolution and treatment and comparing different treatments. However, precise quantification is not feasible for the amount of CT scans required. The purpose of this work is to develop a methodology for quantification of lung damage caused by TB through chest radiographs. It was developed an algorithm for computational processing of exams in Matlab, which creates a lungs' 3D representation, with compromised dilated regions inside. The quantification of lung lesions was also made for the same patients through CT scans. The measurements from the two methods were compared and resulting in strong correlation. Applying statistical Bland and Altman, all samples were within the limits of agreement, with a confidence interval of 95%. The results showed an average variation of around 13% between the two quantification methods. The results suggest the effectiveness and applicability of the method developed, providing better risk-benefit to the patient and cost-benefit ratio for the institution. (author)

  16. Two families with quadrupedalism, mental retardation, no speech, and infantile hypotonia (Uner Tan Syndrome Type-II); a novel theory for the evolutionary emergence of human bipedalism.

    Tan, Uner

    2014-01-01

    Two consanguineous families with Uner Tan Syndrome (UTS) were analyzed in relation to self-organizing processes in complex systems, and the evolutionary emergence of human bipedalism. The cases had the key symptoms of previously reported cases of UTS, such as quadrupedalism, mental retardation, and dysarthric or no speech, but the new cases also exhibited infantile hypotonia and are designated UTS Type-II. There were 10 siblings in Branch I and 12 siblings in Branch II. Of these, there were seven cases exhibiting habitual quadrupedal locomotion (QL): four deceased and three living. The infantile hypotonia in the surviving cases gradually disappeared over a period of years, so that they could sit by about 10 years, crawl on hands and knees by about 12 years. They began walking on all fours around 14 years, habitually using QL. Neurological examinations showed normal tonus in their arms and legs, no Babinski sign, brisk tendon reflexes especially in the legs, and mild tremor. The patients could not walk in a straight line, but (except in one case) could stand up and maintain upright posture with truncal ataxia. Cerebello-vermial hypoplasia and mild gyral simplification were noted in their MRIs. The results of the genetic analysis were inconclusive: no genetic code could be identified as the triggering factor for the syndrome in these families. Instead, the extremely low socio-economic status of the patients was thought to play a role in the emergence of UTS, possibly by epigenetically changing the brain structure and function, with a consequent selection of ancestral neural networks for QL during locomotor development. It was suggested that UTS may be regarded as one of the unpredictable outcomes of self-organization within a complex system. It was also noted that the prominent feature of this syndrome, the diagonal-sequence habitual QL, generated an interference between ipsilateral hands and feet, as in non-human primates. It was suggested that this may have been

  17. Uncertainty Quantification for Safeguards Measurements

    Part of the scientific method requires all calculated and measured results to be accompanied by a description that meets user needs and provides an adequate statement of the confidence one can have in the results. The scientific art of generating quantitative uncertainty statements is closely related to the mathematical disciplines of applied statistics, sensitivity analysis, optimization, and inversion, but in the field of non-destructive assay, also often draws heavily on expert judgment based on experience. We call this process uncertainty quantification, (UQ). Philosophical approaches to UQ along with the formal tools available for UQ have advanced considerably over recent years and these advances, we feel, may be useful to include in the analysis of data gathered from safeguards instruments. This paper sets out what we hope to achieve during a three year US DOE NNSA research project recently launched to address the potential of advanced UQ to improve safeguards conclusions. By way of illustration we discuss measurement of uranium enrichment by the enrichment meter principle (also known as the infinite thickness technique), that relies on gamma counts near the 186 keV peak directly from 235U. This method has strong foundations in fundamental physics and so we have a basis for the choice of response model — although in some implementations, peak area extraction may result in a bias when applied over a wide dynamic range. It also allows us to describe a common but usually neglected aspect of applying a calibration curve, namely the error structure in the predictors. We illustrate this using a combination of measured data and simulation. (author)

  18. Finite-size corrections in the SU(2)xSU(2) sector of type IIA string theory on AdS{sub 4}xCP{sup 3}

    Astolfi, Davide [Dipartimento di Fisica, Universita di Perugia, I.N.F.N. Sezione di Perugia, Via Pascoli, I-06123 Perugia (Italy)], E-mail: astolfi@pg.infn.it; Puletti, Valentina Giangreco M. [Department of Physics and Astronomy, Uppsala University, SE-75108 Uppsala (Sweden)], E-mail: valentina.giangreco@fysast.uu.se; Grignani, Gianluca [Dipartimento di Fisica, Universita di Perugia, I.N.F.N. Sezione di Perugia, Via Pascoli, I-06123 Perugia (Italy)], E-mail: gianluca.grignani@pg.infn.it; Harmark, Troels [Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen O (Denmark)], E-mail: harmark@nbi.dk; Orselli, Marta [The Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen O (Denmark)], E-mail: orselli@nbi.dk

    2009-03-21

    We consider finite-size corrections in the SU(2)xSU(2) sector of type IIA string theory on AdS{sub 4}xCP{sup 3}, which is the string dual of the recently constructed N=6 superconformal Chern-Simons theory of Aharony, Bergman, Jafferis and Maldacena (ABJM theory). The string states we consider are in the RxS{sup 2}xS{sup 2} subspace of AdS{sub 4}xCP{sup 3} with an angular momentum J on CP{sup 3} being large. We compute the finite-size corrections using two different methods, one is to consider curvature corrections to the Penrose limit giving an expansion in 1/J, the other by considering a low energy expansion in {lambda}'={lambda}/J{sup 2} of the string theory sigma-model, {lambda} being the 't Hooft coupling of the dual ABJM theory. For both methods there are interesting issues to deal with. In the near-pp-wave method there is a 1/{radical}(J) interaction term for which we use zeta-function regularization in order to compute the 1/J correction to the energy. For the low energy sigma-model expansion we have to take into account a non-trivial coupling to a non-dynamical transverse direction. We find agreement between the two methods. At order {lambda}' and {lambda}'{sup 2}, for small {lambda}', our results are analogous to the ones for the SU(2) sector in type IIB string theory on AdS{sub 5}xS{sup 5}. Instead at order {lambda}'{sup 3} there are interactions between the two two-spheres. We compare our results with the recently proposed all-loop Bethe ansatz of Gromov and Vieira and find agreement.

  19. MOTIVATION INTERNALIZATION AND SIMPLEX STRUCTURE IN SELF-DETERMINATION THEORY.

    Ünlü, Ali; Dettweiler, Ulrich

    2015-12-01

    Self-determination theory, as proposed by Deci and Ryan, postulated different types of motivation regulation. As to the introjected and identified regulation of extrinsic motivation, their internalizations were described as "somewhat external" and "somewhat internal" and remained undetermined in the theory. This paper introduces a constrained regression analysis that allows these vaguely expressed motivations to be estimated in an "optimal" manner, in any given empirical context. The approach was even generalized and applied for simplex structure analysis in self-determination theory. The technique was exemplified with an empirical study comparing science teaching in a classical school class versus an expeditionary outdoor program. Based on a sample of 84 German pupils (43 girls, 41 boys, 10 to 12 years old), data were collected using the German version of the Academic Self-Regulation Questionnaire. The science-teaching format was seen to not influence the pupils' internalization of identified regulation. The internalization of introjected regulation differed and shifted more toward the external pole in the outdoor teaching format. The quantification approach supported the simplex structure of self-determination theory, whereas correlations may disconfirm the simplex structure. PMID:26595290

  20. Inverse problems Tikhonov theory and algorithms

    Ito, Kazufumi

    2014-01-01

    Inverse problems arise in practical applications whenever one needs to deduce unknowns from observables. This monograph is a valuable contribution to the highly topical field of computational inverse problems. Both mathematical theory and numerical algorithms for model-based inverse problems are discussed in detail. The mathematical theory focuses on nonsmooth Tikhonov regularization for linear and nonlinear inverse problems. The computational methods include nonsmooth optimization algorithms, direct inversion methods and uncertainty quantification via Bayesian inference. The book offers a c

  1. Entanglement quantification by local unitaries

    A. Monras; Adesso, G.; Giampaolo, S. M.; Gualdi, G.; Davies, G. B.; Illuminati, F.

    2011-01-01

    Invariance under local unitary operations is a fundamental property that must be obeyed by every proper measure of quantum entanglement. However, this is not the only aspect of entanglement theory where local unitaries play a relevant role. In the present work we show that the application of suitable local unitary operations defines a family of bipartite entanglement monotones, collectively referred to as "mirror entanglement". They are constructed by first considering the (squared) Hilbert-S...

  2. Separation and quantification of microalgal carbohydrates.

    Templeton, David W; Quinn, Matthew; Van Wychen, Stefanie; Hyman, Deborah; Laurens, Lieve M L

    2012-12-28

    Structural carbohydrates can constitute a large fraction of the dry weight of algal biomass and thus accurate identification and quantification is important for summative mass closure. Two limitations to the accurate characterization of microalgal carbohydrates are the lack of a robust analytical procedure to hydrolyze polymeric carbohydrates to their respective monomers and the subsequent identification and quantification of those monosaccharides. We address the second limitation, chromatographic separation of monosaccharides, here by identifying optimum conditions for the resolution of a synthetic mixture of 13 microalgae-specific monosaccharides, comprised of 8 neutral, 2 amino sugars, 2 uronic acids and 1 alditol (myo-inositol as an internal standard). The synthetic 13-carbohydrate mix showed incomplete resolution across 11 traditional high performance liquid chromatography (HPLC) methods, but showed improved resolution and accurate quantification using anion exchange chromatography (HPAEC) as well as alditol acetate derivatization followed by gas chromatography (for the neutral- and amino-sugars only). We demonstrate the application of monosaccharide quantification using optimized chromatography conditions after sulfuric acid analytical hydrolysis for three model algae strains and compare the quantification and complexity of monosaccharides in analytical hydrolysates relative to a typical terrestrial feedstock, sugarcane bagasse. PMID:23177152

  3. Pancreas++ : Automated Quantification of Pancreatic Islet Cells in Microscopy Images

    StuartMaudsley

    2013-01-01

    Full Text Available The microscopic image analysis of pancreatic Islet of Langerhans morphology is crucial for the investigation of diabetes and metabolic diseases. Besides the general size of the islet, the percentage and relative position of glucagon-containing alpha-, and insulin-containing beta-cells is also important for pathophysiological analyses, especially in rodents. Hence, the ability to identify, quantify and spatially locate peripheral and ‘involuted’ alpha-cells in the islet core is an important analytical goal. There is a dearth of software available for the automated and sophisticated positional-quantification of multiple cell types in the islet core. Manual analytical methods for these analyses, while relatively accurate, can suffer from a slow throughput rate as well as user-based biases. Here we describe a newly developed pancreatic islet analytical software program, Pancreas++, which facilitates the fully-automated, non-biased, and highly reproducible investigation of islet area and alpha- and beta-cell quantity as well as position within the islet for either single or large batches of fluorescent images. We demonstrate the utility and accuracy of Pancreas++ by comparing its performance to other pancreatic islet size and cell type (alpha, beta quantification methods. Our Pancreas++ analysis was significantly faster than other methods, while still retaining low error rates and a high degree of result correlation with the manually generated reference standard.

  4. Xinhe Mine water inrush risk assessment based on quantification theoretical models

    LI Hui; JING Guo-xun; CAI Zheng-long; OU Jian-chun

    2010-01-01

    Taking the Xinhe mine's structure, mine pressure, structural fissure, fault and fault displacement, the distance between fault and water inrush point, thickness of block,water pressure those geological factors which influenced the water inrush as the independent variable, based on these data of water inrush point and water uninrush point, using the method of quantification theory( Ⅰ, Ⅱ ), it would quantitatively disposes the qualitative variable, applied to calculation to evaluate the risk of Xinhe's water inrush.

  5. WaveletQuant, an improved quantification software based on wavelet signal threshold de-noising for labeled quantitative proteomic analysis

    Li Song

    2010-04-01

    Full Text Available Abstract Background Quantitative proteomics technologies have been developed to comprehensively identify and quantify proteins in two or more complex samples. Quantitative proteomics based on differential stable isotope labeling is one of the proteomics quantification technologies. Mass spectrometric data generated for peptide quantification are often noisy, and peak detection and definition require various smoothing filters to remove noise in order to achieve accurate peptide quantification. Many traditional smoothing filters, such as the moving average filter, Savitzky-Golay filter and Gaussian filter, have been used to reduce noise in MS peaks. However, limitations of these filtering approaches often result in inaccurate peptide quantification. Here we present the WaveletQuant program, based on wavelet theory, for better or alternative MS-based proteomic quantification. Results We developed a novel discrete wavelet transform (DWT and a 'Spatial Adaptive Algorithm' to remove noise and to identify true peaks. We programmed and compiled WaveletQuant using Visual C++ 2005 Express Edition. We then incorporated the WaveletQuant program in the Trans-Proteomic Pipeline (TPP, a commonly used open source proteomics analysis pipeline. Conclusions We showed that WaveletQuant was able to quantify more proteins and to quantify them more accurately than the ASAPRatio, a program that performs quantification in the TPP pipeline, first using known mixed ratios of yeast extracts and then using a data set from ovarian cancer cell lysates. The program and its documentation can be downloaded from our website at http://systemsbiozju.org/data/WaveletQuant.

  6. Antioxidant Activity and Validation of Quantification Method for Lycopene Extracted from Tomato.

    Cefali, Letícia Caramori; Cazedey, Edith Cristina Laignier; Souza-Moreira, Tatiana Maria; Correa, Marcos Antônio; Salgado, Hérida Regina Nunes; Isaac, Vera Lucia Borges

    2015-01-01

    Lycopene is a carotenoid found in tomatoes with potent antioxidant activity. The aim of the study was to obtain an extract containing lycopene from four types of tomatoes, validate a quantification method for the extracts by HPLC, and assess its antioxidant activity. Results revealed that the tomatoes analyzed contained lycopene and antioxidant activity. Salad tomato presented the highest concentration of this carotenoid and antioxidant activity. The quantification method exhibited linearity with a correlation coefficient of 0.9992. Tests for the assessment of precision, accuracy, and robustness achieved coefficients with variation of less than 5%. The LOD and LOQ were 0.0012 and 0.0039 μg/mL, respectively. Salad tomato can be used as a source of lycopene for the development of topical formulations, and based on performed tests, the chosen method for the identification and quantification of lycopene was considered to be linear, precise, exact, selective, and robust. PMID:26525253

  7. Techniques for quantification of liver fat in risk stratification of diabetics

    Fatty liver disease plays an important role in the development of type 2 diabetes. Accurate techniques for detection and quantification of liver fat are essential for clinical diagnostics. Chemical shift-encoded magnetic resonance imaging (MRI) is a simple approach to quantify liver fat content. Liver fat quantification using chemical shift-encoded MRI is influenced by several bias factors, such as T2* decay, T1 recovery and the multispectral complexity of fat. The confounder corrected proton density fat fraction is a simple approach to quantify liver fat with comparable results independent of the software and hardware used. The proton density fat fraction is an accurate biomarker for assessment of liver fat. An accurate and reproducible quantification of liver fat using chemical shift-encoded MRI requires a calculation of the proton density fat fraction. (orig.)

  8. RNAontheBENCH: computational and empirical resources for benchmarking RNAseq quantification and differential expression methods.

    Germain, Pierre-Luc; Vitriolo, Alessandro; Adamo, Antonio; Laise, Pasquale; Das, Vivek; Testa, Giuseppe

    2016-06-20

    RNA sequencing (RNAseq) has become the method of choice for transcriptome analysis, yet no consensus exists as to the most appropriate pipeline for its analysis, with current benchmarks suffering important limitations. Here, we address these challenges through a rich benchmarking resource harnessing (i) two RNAseq datasets including ERCC ExFold spike-ins; (ii) Nanostring measurements of a panel of 150 genes on the same samples; (iii) a set of internal, genetically-determined controls; (iv) a reanalysis of the SEQC dataset; and (v) a focus on relative quantification (i.e. across-samples). We use this resource to compare different approaches to each step of RNAseq analysis, from alignment to differential expression testing. We show that methods providing the best absolute quantification do not necessarily provide good relative quantification across samples, that count-based methods are superior for gene-level relative quantification, and that the new generation of pseudo-alignment-based software performs as well as established methods, at a fraction of the computing time. We also assess the impact of library type and size on quantification and differential expression analysis. Finally, we have created a R package and a web platform to enable the simple and streamlined application of this resource to the benchmarking of future methods. PMID:27190234

  9. RNAontheBENCH: computational and empirical resources for benchmarking RNAseq quantification and differential expression methods

    Germain, Pierre-Luc

    2016-06-20

    RNA sequencing (RNAseq) has become the method of choice for transcriptome analysis, yet no consensus exists as to the most appropriate pipeline for its analysis, with current benchmarks suffering important limitations. Here, we address these challenges through a rich benchmarking resource harnessing (i) two RNAseq datasets including ERCC ExFold spike-ins; (ii) Nanostring measurements of a panel of 150 genes on the same samples; (iii) a set of internal, genetically-determined controls; (iv) a reanalysis of the SEQC dataset; and (v) a focus on relative quantification (i.e. across-samples). We use this resource to compare different approaches to each step of RNAseq analysis, from alignment to differential expression testing. We show that methods providing the best absolute quantification do not necessarily provide good relative quantification across samples, that count-based methods are superior for gene-level relative quantification, and that the new generation of pseudo-alignment-based software performs as well as established methods, at a fraction of the computing time. We also assess the impact of library type and size on quantification and differential expression analysis. Finally, we have created a R package and a web platform to enable the simple and streamlined application of this resource to the benchmarking of future methods.

  10. Comparison of five DNA quantification methods

    Nielsen, Karsten; Mogensen, Helle Smidt; Hedman, Johannes;

    2008-01-01

    Six commercial preparations of human genomic DNA were quantified using five quantification methods: UV spectrometry, SYBR-Green dye staining, slot blot hybridization with the probe D17Z1, Quantifiler Human DNA Quantification kit and RB1 rt-PCR. All methods measured higher DNA concentrations than...... expected based on the information by the manufacturers. UV spectrometry, SYBR-Green dye staining, slot blot and RB1 rt-PCR gave 39, 27, 11 and 12%, respectively, higher concentrations than expected based on the manufacturers' information. The DNA preparations were quantified using the Quantifiler Human DNA...... Quantification kit in two experiments. The measured DNA concentrations with Quantifiler were 125 and 160% higher than expected based on the manufacturers' information. When the Quantifiler human DNA standard (Raji cell line) was replaced by the commercial human DNA preparation G147A (Promega) to generate the DNA...

  11. Rationality, Theory Acceptance and Decision Theory

    J. Nicolas Kaufmann

    1998-06-01

    Full Text Available Following Kuhn's main thesis according to which theory revision and acceptance is always paradigm relative, I propose to outline some possible consequences of such a view. First, asking the question in what sense Bayesian decision theory could serve as the appropriate (normative theory of rationality examined from the point of view of the epistemology of theory acceptance, I argue that Bayesianism leads to a narrow conception of theory acceptance. Second, regarding the different types of theory revision, i.e. expansion, contraction, replacement and residuals shifts, I extract from Kuhn's view a series of indications showing that theory replacement cannot be rationalized within the framework of Bayesian decision theory, not even within a more sophisticated version of that model. Third, and finally, I will point to the need for a more comprehensive model of rationality than the Bayesian expected utility maximization model, the need for a model which could better deal with the different aspects of theory replacement. I will show that Kuhn's distinction between normal and revolutionary science gives us several hints for a more adequate theory of rationality in science. I will also show that Kuhn is not in a position to fully articulate his main ideas and that he well be confronted with a serious problem concerning collective choice of a paradigm.

  12. Application of adaptive hierarchical sparse grid collocation to the uncertainty quantification of nuclear reactor simulators

    Yankov, A.; Downar, T. [University of Michigan, 2355 Bonisteel Blvd, Ann Arbor, MI 48109 (United States)

    2013-07-01

    Recent efforts in the application of uncertainty quantification to nuclear systems have utilized methods based on generalized perturbation theory and stochastic sampling. While these methods have proven to be effective they both have major drawbacks that may impede further progress. A relatively new approach based on spectral elements for uncertainty quantification is applied in this paper to several problems in reactor simulation. Spectral methods based on collocation attempt to couple the approximation free nature of stochastic sampling methods with the determinism of generalized perturbation theory. The specific spectral method used in this paper employs both the Smolyak algorithm and adaptivity by using Newton-Cotes collocation points along with linear hat basis functions. Using this approach, a surrogate model for the outputs of a computer code is constructed hierarchically by adaptively refining the collocation grid until the interpolant is converged to a user-defined threshold. The method inherently fits into the framework of parallel computing and allows for the extraction of meaningful statistics and data that are not within reach of stochastic sampling and generalized perturbation theory. This paper aims to demonstrate the advantages of spectral methods-especially when compared to current methods used in reactor physics for uncertainty quantification-and to illustrate their full potential. (authors)

  13. Uncertainty quantification metrics for whole product life cycle cost estimates in aerospace innovation

    Schwabe, O.; Shehab, E.; Erkoyuncu, J.

    2015-08-01

    The lack of defensible methods for quantifying cost estimate uncertainty over the whole product life cycle of aerospace innovations such as propulsion systems or airframes poses a significant challenge to the creation of accurate and defensible cost estimates. Based on the axiomatic definition of uncertainty as the actual prediction error of the cost estimate, this paper provides a comprehensive overview of metrics used for the uncertainty quantification of cost estimates based on a literature review, an evaluation of publicly funded projects such as part of the CORDIS or Horizon 2020 programs, and an analysis of established approaches used by organizations such NASA, the U.S. Department of Defence, the ESA, and various commercial companies. The metrics are categorized based on their foundational character (foundations), their use in practice (state-of-practice), their availability for practice (state-of-art) and those suggested for future exploration (state-of-future). Insights gained were that a variety of uncertainty quantification metrics exist whose suitability depends on the volatility of available relevant information, as defined by technical and cost readiness level, and the number of whole product life cycle phases the estimate is intended to be valid for. Information volatility and number of whole product life cycle phases can hereby be considered as defining multi-dimensional probability fields admitting various uncertainty quantification metric families with identifiable thresholds for transitioning between them. The key research gaps identified were the lacking guidance grounded in theory for the selection of uncertainty quantification metrics and lacking practical alternatives to metrics based on the Central Limit Theorem. An innovative uncertainty quantification framework consisting of; a set-theory based typology, a data library, a classification system, and a corresponding input-output model are put forward to address this research gap as the basis

  14. Molecular quantification of genes encoding for green-fluorescent proteins

    Felske, A; Vandieken, V; Pauling, B V;

    2003-01-01

    A quantitative PCR approach is presented to analyze the amount of recombinant green fluorescent protein (gfp) genes in environmental DNA samples. The quantification assay is a combination of specific PCR amplification and temperature gradient gel electrophoresis (TGGE). Gene quantification...

  15. Advancing agricultural greenhouse gas quantification*

    Olander, Lydia; Wollenberg, Eva; Tubiello, Francesco; Herold, Martin

    2013-03-01

    1. Introduction Better information on greenhouse gas (GHG) emissions and mitigation potential in the agricultural sector is necessary to manage these emissions and identify responses that are consistent with the food security and economic development priorities of countries. Critical activity data (what crops or livestock are managed in what way) are poor or lacking for many agricultural systems, especially in developing countries. In addition, the currently available methods for quantifying emissions and mitigation are often too expensive or complex or not sufficiently user friendly for widespread use. The purpose of this focus issue is to capture the state of the art in quantifying greenhouse gases from agricultural systems, with the goal of better understanding our current capabilities and near-term potential for improvement, with particular attention to quantification issues relevant to smallholders in developing countries. This work is timely in light of international discussions and negotiations around how agriculture should be included in efforts to reduce and adapt to climate change impacts, and considering that significant climate financing to developing countries in post-2012 agreements may be linked to their increased ability to identify and report GHG emissions (Murphy et al 2010, CCAFS 2011, FAO 2011). 2. Agriculture and climate change mitigation The main agricultural GHGs—methane and nitrous oxide—account for 10%-12% of anthropogenic emissions globally (Smith et al 2008), or around 50% and 60% of total anthropogenic methane and nitrous oxide emissions, respectively, in 2005. Net carbon dioxide fluxes between agricultural land and the atmosphere linked to food production are relatively small, although significant carbon emissions are associated with degradation of organic soils for plantations in tropical regions (Smith et al 2007, FAO 2012). Population growth and shifts in dietary patterns toward more meat and dairy consumption will lead to

  16. Quantification of resonance interference effect for multi-group effective cross-section in lattice physics calculation

    This paper presents the quantification of resonance interference effect for multi-group effective cross-section in lattice physics calculation. In the resonance self-shielding method based on the equivalence theory, the resonance interference effect among multiple nuclides cannot be treated directly to the multi-group effective cross-section. The continuous energy or the ultra-fine-group treatment can directly consider the effect, but the application to the fuel assembly geometry is not realistic with practical computation time. In the present study, the resonance interference effect to the multi-group effective cross-section is simply quantified by the resonance interference factor (RIF) in order to confirm the benefit for considering the effect. The RIF is generated for the typical pin-cell geometry of water moderated system. The multi-group effective cross-sections with and without RIFs are compared with the continuous energy Monte-Carlo result. As a result, the significant impact for considering the resonance interference effect is confirmed to the limited nuclide, reaction type and energy group. Fortunately, these have small effect on k-infinity because the resonance interference effect is mainly induced by the wide resonances of 238U to the other minor nuclides (e.g., 235U, 239Pu) in the limited resonance energy ranges. The results also show that the effect is small to the absorption cross-section of 238U, which is the dominant resonance nuclide in the fuel. The quantification results in the present study indicate a useful material to investigate the more advanced resonance treatment for the next generation lattice physics code. (author)

  17. Introduction to superstring theory

    This is a very basic introduction to the AdS/CFT correspondence. The first lecture motivates the duality between gauge theories and gravity/string theories. The next two lectures introduce the bosonic and supersymmetric string theories. The fourth lecture is devoted to study Dp-branes and finally, in the fifth lecture I discuss the two worlds: N=4 SYM in 3+1 flat dimensions and type IIB superstrings in AdS5 x S5. (author)

  18. Introduction to superstring theory

    Nunez, Carmen [Instituto de Astronomia y Fisica del Espacio, Buenos Aires (Argentina)], e-mail: carmen@iafe.uba.ar

    2009-07-01

    This is a very basic introduction to the AdS/CFT correspondence. The first lecture motivates the duality between gauge theories and gravity/string theories. The next two lectures introduce the bosonic and supersymmetric string theories. The fourth lecture is devoted to study Dp-branes and finally, in the fifth lecture I discuss the two worlds: N=4 SYM in 3+1 flat dimensions and type IIB superstrings in AdS{sub 5} x S5. (author)

  19. Quantifications and Modeling of Human Failure Events in a Fire PSA

    USNRC and EPRI developed guidance, 'Fire Human Reliability Analysis Guidelines, NUREG-1921', for estimating human error probabilities (HEPs) for HFEs under fire conditions. NUREG-1921 classifies HFEs into four types associated with the following human actions: - Type 1: New and existing Main Control Room (MCR) actions - Type 2: New and existing ex-MCR actions - Type 3: Actions associated with using alternate shutdown means (ASD) - Type 4: Actions relating to the error of commissions (EOCs) or error of omissions (EOOs) as a result of incorrect indications (SPI) In this paper, approaches for the quantifications and modeling of HFEs related to Type 1, 2 and 3 human actions are introduced. This paper introduced the human reliability analysis process for a fire PSA of Hanul Unit 3. A multiplier of 10 was used to re-estimate the HEPs for the preexisting internal human actions. The HEPs for all ex- MCR actions were assumed to be one. New MCR human actions were quantified using the scoping analysis method of NUREG-1921. If the quantified human action were identified to be risk-significant, detailed approaches (modeling and quantification) were used for incorporating fire situations into them. Multiple HFEs for single human action were defined and they were separately and were separately quantified to incorporate the specific fire situations into them. From this study, we can confirm that the modeling as well as quantifications of human actions is very important to appropriately treat them in PSA logic structures

  20. Entanglement in Theory Space

    Yamazaki, Masahito

    2013-01-01

    We propose a new concept of entanglement for quantum systems: entanglement in theory space. This is defined by decomposing a theory into two by an un-gauging procedure. We provide two examples where this newly-introduced entanglement is closely related with conventional geometric entropies: deconstruction and AGT-type correspondence.

  1. Uncovering the underlying physical mechanisms of biological systems via quantification of landscape and flux

    Li, Xu; Xiakun, Chu; Zhiqiang, Yan; Xiliang, Zheng; Kun, Zhang; Feng, Zhang; Han, Yan; Wei, Wu; Jin, Wang

    2016-01-01

    In this review, we explore the physical mechanisms of biological processes such as protein folding and recognition, ligand binding, and systems biology, including cell cycle, stem cell, cancer, evolution, ecology, and neural networks. Our approach is based on the landscape and flux theory for nonequilibrium dynamical systems. This theory provides a unifying principle and foundation for investigating the underlying mechanisms and physical quantification of biological systems. Project supported by the Natural Science Foundation of China (Grant Nos. 21190040, 11174105, 91225114, 91430217, and 11305176) and Jilin Province Youth Foundation, China (Grant No. 20150520082JH).

  2. Entanglement quantification by local unitaries

    Monras, A; Giampaolo, S M; Gualdi, G; Davies, G B; Illuminati, F

    2011-01-01

    Invariance under local unitary operations is a fundamental property that must be obeyed by every proper measure of quantum entanglement. However, this is not the only aspect of entanglement theory where local unitaries play a relevant role. In the present work we show that the application of suitable local unitary operations defines a family of bipartite entanglement monotones, collectively referred to as "shield entanglement". They are constructed by first considering the (squared) Hilbert- Schmidt distance of the state from the set of states obtained by applying to it a given local unitary. To the action of each different local unitary there corresponds a different distance. We then minimize these distances over the sets of local unitaries with different spectra, obtaining an entire family of different entanglement monotones. We show that these shield entanglement monotones are organized in a hierarchical structure, and we establish the conditions that need to be imposed on the spectrum of a local unitary f...

  3. String Theory Without Branes

    Johnson, C V

    2006-01-01

    We present a class of solvable models that resemble string theories in many respects but have a strikingly different non-perturbative sector. In particular, there are no exponentially small contributions to perturbation theory in the string coupling, which normally are associated with branes and related objects. Perturbation theory is no longer an asymptotic expansion, and so can be completely re-summed to yield all the non-perturbative physics. We examine a number of other properties of the theories, for example constructing and examining the physics of loop operators, which can be computed exactly, and gain considerable understanding of the difference between these new theories and the more familiar ones, including the possibility of how to interpolate between the two types. Interestingly, the models we exhibit contain a family of zeros of the partition function which suggest a novel phase structure. The theories are defined naturally by starting with models that yield well-understood string theories and al...

  4. HPC Analytics Support. Requirements for Uncertainty Quantification Benchmarks

    Paulson, Patrick R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Purohit, Sumit [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rodriguez, Luke R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-05-01

    This report outlines techniques for extending benchmark generation products so they support uncertainty quantification by benchmarked systems. We describe how uncertainty quantification requirements can be presented to candidate analytical tools supporting SPARQL. We describe benchmark data sets for evaluating uncertainty quantification, as well as an approach for using our benchmark generator to produce data sets for generating benchmark data sets.

  5. Integrating theory and data to create an online self-management programme for adults with type 2 diabetes: HeLP-Diabetes

    Kingshuk Pal; Charlotte Dack; Susan Michie

    2015-01-01

    Background The prevalence of type 2 diabetes is increasing and estimates suggest that by 2030 nearly 1 in 10 adults worldwide will be living with this condition. 10% of the NHS budget is spent on treating diabetes and related complications like heart attacks, strokes and blindness. Improving self-management in people living with type 2 diabetes is crucial in reducing the morbidity and mortality associated with this disease. Uptake of group-based self-management training is low and there i...

  6. Automated quantification and analysis of mandibular asymmetry

    Darvann, T. A.; Hermann, N. V.; Larsen, P.; Ólafsdóttir, Hildur; Hansen, I. V.; Hove, H. D.; Christensen, L.; Rueckert, D.; Kreiborg, S.

    We present an automated method of spatially detailed 3D asymmetry quantification in mandibles extracted from CT and apply it to a population of infants with unilateral coronal synostosis (UCS). An atlas-based method employing non-rigid registration of surfaces is used for determining deformation...

  7. Perfusion Quantification Using Gaussian Process Deconvolution

    Andersen, Irene Klærke; Have, Anna Szynkowiak; Rasmussen, Carl Edward; Hansson, Lars; Marstrand, J. R.; Larsson, Henrik B.W.; Hansen, Lars Kai

    2002-01-01

    The quantification of perfusion using dynamic susceptibility contrast MRI (DSC-MRI) requires deconvolution to obtain the residual impulse response function (IRF). In this work, a method using the Gaussian process for deconvolution (GPD) is proposed. The fact that the IRF is smooth is incorporated...

  8. Anwendung der "Uncertainty Quantification" bei eisenbahndynamischen problemen

    Bigoni, Daniele; Engsig-Karup, Allan Peter; True, Hans

    The paper describes the results of the application of "Uncertainty Quantification" methods in railway vehicle dynamics. The system parameters are given by probability distributions. The results of the application of the Monte-Carlo and generalized Polynomial Chaos methods to a simple bogie model...

  9. Recurrence quantification analysis in Liu's attractor

    Recurrence Quantification Analysis is used to detect transitions chaos to periodical states or chaos to chaos in a new dynamical system proposed by Liu et al. This system contains a control parameter in the second equation and was originally introduced to investigate the forming mechanism of the compound structure of the chaotic attractor which exists when the control parameter is zero

  10. Cues, quantification, and agreement in language comprehension.

    Tanner, Darren; Bulkes, Nyssa Z

    2015-12-01

    We investigated factors that affect the comprehension of subject-verb agreement in English, using quantification as a window into the relationship between morphosyntactic processes in language production and comprehension. Event-related brain potentials (ERPs) were recorded while participants read sentences with grammatical and ungrammatical verbs, in which the plurality of the subject noun phrase was either doubly marked (via overt plural quantification and morphological marking on the noun) or singly marked (via only plural morphology on the noun). Both acceptability judgments and the ERP data showed heightened sensitivity to agreement violations when quantification provided an additional cue to the grammatical number of the subject noun phrase, over and above plural morphology. This is consistent with models of grammatical comprehension that emphasize feature prediction in tandem with cue-based memory retrieval. Our results additionally contrast with those of prior studies that showed no effects of plural quantification on agreement in language production. These findings therefore highlight some nontrivial divergences in the cues and mechanisms supporting morphosyntactic processing in language production and comprehension. PMID:25987192

  11. Efficient uncertainty quantification in unsteady aeroelastic simulations

    Witteveen, J.A.S.; Bijl, H.

    2009-01-01

    An efficient uncertainty quantification method for unsteady problems is presented in order to achieve a constant accuracy in time for a constant number of samples. The approach is applied to the aeroelastic problems of a transonic airfoil flutter system and the AGARD 445.6 wing benchmark with uncert

  12. Gauge Theories of Gravitation

    Blagojević, Milutin

    2012-01-01

    During the last five decades, gravity, as one of the fundamental forces of nature, has been formulated as a gauge field theory of the Weyl-Cartan-Yang-Mills type. The resulting theory, the Poincar\\'e gauge theory of gravity, encompasses Einstein's gravitational theory as well as the teleparallel theory of gravity as subcases. In general, the spacetime structure is enriched by Cartan's torsion and the new theory can accommodate fermionic matter and its spin in a perfectly natural way. The present reprint volume contains articles from the most prominent proponents of the theory and is supplemented by detailed commentaries of the editors. This guided tour starts from special relativity and leads, in its first part, to general relativity and its gauge type extensions a la Weyl and Cartan. Subsequent stopping points are the theories of Yang-Mills and Utiyama and, as a particular vantage point, the theory of Sciama and Kibble. Later, the Poincar\\'e gauge theory and its generalizations are explored and specific topi...

  13. Topological field theory

    We begin with a general discussion of topological field theories, their defining properties, and classification. The first model we consider in detail (section 3) is supersymmetric quantum mechanics. Topological sigma models, their observables, and the associated mathematics of complex geometry and intersection theory are presented in section 4. Following this, topological gauge theories are discussed in section 5, with particular emphasis on Donaldson theory. The matematics here is necessarily much more sophisticated than at any other point in this report, and to bridge this gap, a mathematical review of gauge theory and moduli spaces has been included. An analysis of the geometry underlying Donaldson theory gives a general recipe for constructing field theories associated to moduli spaces in arbitrary dimensions, and as an example, we analyze in detail the super BF theories associated with flat connections. Chern-Simons theory and related BF models are the subject of section 6. The connections with knot theory are briefly reviewed and the link with 2D conformal field theory is sketched. We also consider 3D gravity from the Chern-Simons point of view. A presentation of the metric and gauge theory approaches to topological gravity in two dimensions is given. As in all quantum field theories, the issues of renormalization needs to be addressed, and one is obliged to show that the formal topological properties of these theories survive quantization. This point is considered in section 8. We present a detailed analysis of the beta function in certain Witten type theories, and compute one-loop effects in Chern-Simons theory. (orig./HSI)

  14. Topological field theory

    Birmingham, D. (CERN, Geneva (Switzerland). Theory Div.); Blau, M. (CNRS, 13 - Marseille (France). Centre de Physique Theorique NIKHEF-H, Amsterdam (Netherlands)); Rakowski, M.; Thompson, G. (Mainz Univ. (Germany). Inst. fuer Physik)

    1991-12-01

    We begin with a general discussion of topological field theories, their defining properties, and classification. The first model we consider in detail (section 3) is supersymmetric quantum mechanics. Topological sigma models, their observables, and the associated mathematics of complex geometry and intersection theory are presented in section 4. Following this, topological gauge theories are discussed in section 5, with particular emphasis on Donaldson theory. The matematics here is necessarily much more sophisticated than at any other point in this report, and to bridge this gap, a mathematical review of gauge theory and moduli spaces has been included. An analysis of the geometry underlying Donaldson theory gives a general recipe for constructing field theories associated to moduli spaces in arbitrary dimensions, and as an example, we analyze in detail the super BF theories associated with flat connections. Chern-Simons theory and related BF models are the subject of section 6. The connections with knot theory are briefly reviewed and the link with 2D conformal field theory is sketched. We also consider 3D gravity from the Chern-Simons point of view. A presentation of the metric and gauge theory approaches to topological gravity in two dimensions is given. As in all quantum field theories, the issues of renormalization needs to be addressed, and one is obliged to show that the formal topological properties of these theories survive quantization. This point is considered in section 8. We present a detailed analysis of the beta function in certain Witten type theories, and compute one-loop effects in Chern-Simons theory. (orig./HSI).

  15. Uncertainty quantification in aerosol dynamics

    The influence of uncertainty in coagulation and depositions mechanisms, as well as in the initial conditions, on the solution of the aerosol dynamic equation have been assessed using polynomial chaos theory. In this way, large uncertainties can be incorporated into the equations and their propagation as a function of space and time studied. We base our calculations on the simplified point model dynamic equation which includes coagulation and deposition removal mechanisms. Results are given for the stochastic mean aerosol density as a function of time as well as its variance. The stochastic mean and deterministic mean are shown to differ and the associated uncertainty, in the form of a sensitivity coefficient, is obtained as a function of time. In addition, we obtain the probability density function of the aerosol density and show how this varies with time. In view of the generally uncertain nature of an accidental aerosol release in a nuclear reactor accident, the polynomial chaos method is a particularly useful technique as it allows one to deal with a very large spread of input data and examine the effect this has on the quantities of interest. Convergence matters are studied and numerical values given.

  16. The effect of surfaces type on vibration behavior of piezoelectric micro-cantilever close to sample surface in a humid environment based on MCS theory

    Korayem, M. H.; Korayem, A. H.

    2016-08-01

    Atomic force microscopy (AFM) has been known as an innovative tool in the fields of surface topography, determination of different mechanical properties and manipulation of particles at the micro- and nanoscales. This paper has been concerned with advanced modeling and dynamic simulation of AFM micro-cantilever (MC) in the amplitude mode in the air environment. To increase the accuracy of the governing equations, modified couple stress theory appropriate in micro- and nanoscales has been utilized based on Timoshenko beam theory in the air environment near the sample surface. Also, to discretize the equations, differential quadrature method has been recommended. In modeling, geometric discontinuities due to the presence of a piezoelectric layer enclosed between two electrode layers and the change in MC cross section when connected to the MC have been considered. In addition to the effect of MC modeling on the accuracy of modeling and vibration amplitude during surface topography, understanding and modeling the environmental forces in the air environment, including van der Waals, capillary and contact forces, are important. This paper has been provided more accurate environmental forces modeling and has been investigated the vibration behavior of piezoelectric MC in the humid environment. Moreover, this paper has been examined the maximum and minimum MC amplitude in the air environment close to the surface with different kinds of topography. The results illustrate that kind of surfaces has effect on the maximum and minimum amplitude due to the decrease or increase in equilibrium MC distance.

  17. Options theory

    Techniques used in conventional project appraisal are mathematically very simple in comparison to those used in reservoir modelling, and in the geosciences. Clearly it would be possible to value assets in mathematically more sophisticated ways if it were meaningful and worthwhile so to do. The DCf approach in common use has recognized limitations; the inability to select a meaningful discount rate being particularly significant. Financial Theory has advanced enormously over the last few years, along with computational techniques, and methods are beginning to appear which may change the way we do project evaluations in practice. The starting point for all of this was a paper by Black and Scholes, which asserts that almost all corporate liabilities can be viewed as options of varying degrees of complexity. Although the financial presentation may be unfamiliar to engineers and geoscientists, some of the concepts used will not be. This paper outlines, in plain English, the basis of option pricing theory for assessing the market value of a project. it also attempts to assess the future role of this type of approach in practical Petroleum Exploration and Engineering economics. Reference is made to relevant published Natural Resource literature

  18. Uncertainty quantification methodology development for the best-estimate safety analysis

    This study deals with two approaches to uncertainty quantification methodology. In the first approach, an uncertainty quantification methodology is proposed and applied to the estimation of nuclear reactor fuel peak cladding temperature (PCT) uncertainty. The proposed method adopts the use of Latin hypercube sampling (LHS). The independency between the input variables is verified through a correlation coefficient test. The uncertainty of the output variables is estimated through a goodness-of-fit test on the sample data. In the application, the approach taken to quantifying the total mean and total 95% probability PCTs is given. Emphasis is placed upon the PCT uncertainty estimation due to models' or correlations' uncertainties with the assumption that significant sources of PCT uncertainty are determined. In the second approach, an uncertainty quantification methodology is proposed for a severe accident analysis which has large uncertainties. The proposed method adopts the concept of probabilistic belief measure to transform an analyst's belief on a top event into the equivalent probability of that top event. For the purpose of comparison, analyses are done by 1) applying probability theory regarding the occurring probability of top event as a physical probability or a frequency, 2) applying fuzzy set theory with fuzzy numbered occurring probability of top event, and 3) transforming the analysts' belief on the top event into equivalent probability by the probabilistic belief measure method

  19. Waltz's Theory of Theory

    Wæver, Ole

    2009-01-01

    Kenneth N. Waltz's 1979 book, Theory of International Politics, is the most influential in the history of the discipline. It worked its effects to a large extent through raising the bar for what counted as theoretical work, in effect reshaping not only realism but rivals like liberalism and......-empiricism and anti-positivism of his position. Followers and critics alike have treated Waltzian neorealism as if it was at bottom a formal proposition about cause-effect relations. The extreme case of Waltz being so victorious in the discipline, and yet being consistently mis-interpreted on the question of...

  20. Ring Theory

    Jara, Pascual; Torrecillas, Blas

    1988-01-01

    The papers in this proceedings volume are selected research papers in different areas of ring theory, including graded rings, differential operator rings, K-theory of noetherian rings, torsion theory, regular rings, cohomology of algebras, local cohomology of noncommutative rings. The book will be important for mathematicians active in research in ring theory.

  1. String theory

    Marino Beiras, Marcos

    2001-01-01

    We give an overview of the relations between matrix models and string theory, focusing on topological string theory and the Dijkgraaf--Vafa correspondence. We discuss applications of this correspondence and its generalizations to supersymmetric gauge theory, enumerative geometry and mirror symmetry. We also present a brief overview of matrix quantum mechanical models in superstring theory.

  2. A surrogate accelerated multicanonical Monte Carlo method for uncertainty quantification

    Wu, Keyi; Li, Jinglai

    2016-09-01

    In this work we consider a class of uncertainty quantification problems where the system performance or reliability is characterized by a scalar parameter y. The performance parameter y is random due to the presence of various sources of uncertainty in the system, and our goal is to estimate the probability density function (PDF) of y. We propose to use the multicanonical Monte Carlo (MMC) method, a special type of adaptive importance sampling algorithms, to compute the PDF of interest. Moreover, we develop an adaptive algorithm to construct local Gaussian process surrogates to further accelerate the MMC iterations. With numerical examples we demonstrate that the proposed method can achieve several orders of magnitudes of speedup over the standard Monte Carlo methods.

  3. A Point-Wise Quantification of Asymmetry Using Deformation Fields

    Ólafsdóttir, Hildur; Lanche, Stephanie; Darvann, Tron Andre;

    2007-01-01

    resulting displacement vectors on the left and right side of the symmetry plane, gives a point-wise measure of asymmetry. The asymmetry measure was applied to the study of Crouzon syndrome using Micro CT scans of genetically modified mice. Crouzon syndrome is characterised by the premature fusion of cranial......This paper introduces a novel approach to quantify asymmetry in each point of a surface. The measure is based on analysing displacement vectors resulting from nonrigid image registration. A symmetric atlas, generated from control subjects is registered to a given subject image. A comparison of the...... sutures, which gives rise to a highly asymmetric growth. Quantification and localisation of this asymmetry is of high value with respect to surgery planning and treatment evaluation. Using the proposed method, asymmetry was calculated in each point of the surface of Crouzon mice and wild-type mice...

  4. Uncertainty quantification of an inflatable/rigidizable torus

    Lew, Jiann-Shiun; Horta, Lucas G.; Reaves, Mercedes C.

    2006-06-01

    There is an increasing interest in lightweight inflatable structures for space missions. The dynamic testing and model updating of these types of structures present many challenges in terms of model uncertainty and structural nonlinearity. This paper presents an experimental study of uncertainty quantification of a 3m-diameter inflatable torus. Model uncertainty can be thought of as coming from two different sources, uncertainty due to changes in controlled conditions, such as temperature and input force level, and uncertainty associated with others random factors, such as measurement noise, etc. To precisely investigate and quantify model uncertainty from different sources, experiments, using sine-sweep excitation in the specified narrow frequency bands, are conducted to collect frequency response function (FRF) under various test conditions. To model the variation of the identified parameters, a singular value decomposition technique is applied to extract the principal components of the parameter change.

  5. String Theory: Lessons for Low Energy Physics

    Dine, Michael

    1992-01-01

    This talk considers possible lessons of string theory for low energy physics. These are of two types. First, assuming that string theory is the correct underlying theory of all interactions, we ask whether there are any generic predictions the theory makes, and we compare the predictions of string theory with those of conventional grand unified theories. Second, string theory offers some possible answers to a number of troubling naturalness questions. These include problems of discrete and co...

  6. Predicting the consumption of foods low in saturated fats among people diagnosed with Type 2 diabetes and cardiovascular disease. The role of planning in the theory of planned behaviour.

    White, Katherine M; Terry, Deborah J; Troup, Carolyn; Rempel, Lynn A; Norman, Paul

    2010-10-01

    The present study tested the utility of an extended version of the theory of planned behaviour that included a measure of planning, in the prediction of eating foods low in saturated fats among adults diagnosed with Type 2 diabetes and/or cardiovascular disease. Participants (N=184) completed questionnaires assessing standard theory of planned behaviour measures (attitude, subjective norm, and perceived behavioural control) and the additional volitional variable of planning in relation to eating foods low in saturated fats. Self-report consumption of foods low insaturated fats was assessed 1 month later. In partial support of the theory of planned behaviour, results indicated that attitude and subjective norm predicted intentions to eat foods low in saturated fats and intentions and perceived behavioural control predicted the consumption of foods low in saturated fats. As an additional variable, planning predicted the consumption of foods low in saturated fats directly and also mediated the intention-behaviour and perceived behavioural control-behaviour relationships, suggesting an important role for planning as a post-intentional construct determining healthy eating choices. Suggestions are offered for interventions designed to improve adherence to healthy eating recommendations for people diagnosed with these chronic conditions with a specific emphasis on the steps and activities that are required to promote a healthier lifestyle. PMID:20674639

  7. Geographical Theories

    Golledge, Reginald G.

    2001-01-01

    The emergence of geographical theory was an inevitable product of the desire to systematize existing geographic knowledge and to use that systematized base to explore new areas of knowledge. Although the usefulness of theory and predictive models in geography is by now a matter of record, it was not always the case. The usefulness and need for theories was often disputed, despite the oft-repeated argument that theories of location explained the laws of spatial distributions, theories of inter...

  8. String theory

    The paper traces the development of the String Theory, and was presented at Professor Sir Rudolf Peierls' 80sup(th) Birthday Symposium. The String theory is discussed with respect to the interaction of strings, the inclusion of both gauge theory and gravitation, inconsistencies in the theory, and the role of space-time. The physical principles underlying string theory are also outlined. (U.K.)

  9. SPECT quantification of regional radionuclide distributions

    SPECT quantification of regional radionuclide activities within the human body is affected by several physical and instrumental factors including attenuation of photons within the patient, Compton scattered events, the system's finite spatial resolution and object size, finite number of detected events, partial volume effects, the radiopharmaceutical biokinetics, and patient and/or organ motion. Furthermore, other instrumentation factors such as calibration of the center-of-rotation, sampling, and detector nonuniformities will affect the SPECT measurement process. These factors are described, together with examples of compensation methods that are currently available for improving SPECT quantification. SPECT offers the potential to improve in vivo estimates of absorbed dose, provided the acquisition, reconstruction, and compensation procedures are adequately implemented and utilized. 53 references, 2 figures

  10. Quantification of carotid vessel atherosclerosis

    Chiu, Bernard; Egger, Micaela; Spence, J. D.; Parraga, Grace; Fenster, Aaron

    2006-03-01

    Atherosclerosis is characterized by the development of plaques in the arterial wall, which ultimately leads to heart attacks and stroke. 3D ultrasound (US) has been used to screen patients' carotid arteries. Plaque measurements obtained from these images may aid in the management and monitoring of patients, and in evaluating the effect of new treatment options. Different types of measures for ultrasound phenotypes of atherosclerosis have been proposed. Here, we report on the development and application of a method used to analyze changes in carotid plaque morphology from 3D US images obtained at two different time points. We evaluated our technique using manual segmentations of the wall and lumen of the carotid artery from images acquired in two US scanning sessions. To incorporate the effect of intraobserver variability in our evaluation, manual segmentation was performed five times each for the arterial wall and lumen. From this set of five segmentations, the mean wall and lumen surfaces were reconstructed, with the standard deviation at each point mapped onto the surfaces. A correspondence map between the mean wall and lumen surfaces was then established, and the thickness of the atherosclerotic plaque at each point in the vessel was estimated to be the distance between each correspondence pairs. The two-sample Student's t-test was used to judge whether the difference between the thickness values at each pair corresponding points of the arteries in the two 3D US images was statistically significant.

  11. A Tableaux Calculus for Ambiguous Quantification

    Monz, Christof; de Rijke, Maarten

    2000-01-01

    Coping with ambiguity has recently received a lot of attention in natural language processing. Most work focuses on the semantic representation of ambiguous expressions. In this paper we complement this work in two ways. First, we provide an entailment relation for a language with ambiguous expressions. Second, we give a sound and complete tableaux calculus for reasoning with statements involving ambiguous quantification. The calculus interleaves partial disambiguation steps with steps in a t...

  12. Automated Quantification of Pneumothorax in CT

    Synho Do; Kristen Salvaggio; Supriya Gupta; Mannudeep Kalra; Ali, Nabeel U.; Homer Pien

    2012-01-01

    An automated, computer-aided diagnosis (CAD) algorithm for the quantification of pneumothoraces from Multidetector Computed Tomography (MDCT) images has been developed. Algorithm performance was evaluated through comparison to manual segmentation by expert radiologists. A combination of two-dimensional and three-dimensional processing techniques was incorporated to reduce required processing time by two-thirds (as compared to similar techniques). Volumetric measurements on relative pneumothor...

  13. Program Theory Evaluation: Logic Analysis

    Brousselle, Astrid; Champagne, Francois

    2011-01-01

    Program theory evaluation, which has grown in use over the past 10 years, assesses whether a program is designed in such a way that it can achieve its intended outcomes. This article describes a particular type of program theory evaluation--logic analysis--that allows us to test the plausibility of a program's theory using scientific knowledge.…

  14. CP violation in gauge theories

    Einhorn, Martin B; Wudka, Jose

    2000-01-01

    We define the CP transformation properties of scalars, fermions and vectors in a gauge theory and show that only three types of interactions can lead to CP violation: scalar interactions, fermion-scalar interactions and $ F \\tilde F $ associated with the strong CP problem and which involve only the gauge fields. For technicolor theories this implies the absence of CP violation within perturbation theory.

  15. A Type System for Parallel Components

    de Carvalho-Junior, Francisco Heron; Lins, Rafael Dueire

    2009-01-01

    The # component model was proposed to improve the practice of parallel programming. This paper introduces a type system for # programming systems, aiming to lift the abstraction and safety of programming for parallel computing architectures by introducing a notion of abstract component based on universal and existential bounded quantification. Issues about the implementation of such type system in HPE, a # programming system, are also discussed.

  16. Development Research on Leading Type 3PL Based on Incubation Theory%基于孵化理论的领衔式3PL企业发展研究

    王利; 李白艳; 李健

    2013-01-01

    基于3PL及物流业发展现状和社会经济对物流行业发展的客观要求,提出用孵化理论与方法来培育和发展领衔式3PL企业;论述领衔式3PL含义、功能、发展的必要性与困难性,分析孵化领衔式3PL的可行性,提出孵化领衔式3PL的载体、功能与对象.%Based on the present development situation of 3PL and logistic industry and the objective request of social economy to logistic industry,incubation theory was introduced to cultivate and develop the leading type 3PL enterprise.The definition,function,development necessity and difficulty of leading type 3PL were discussed; the possibility of incubating leading type 3PL was analyzed the carrier,function and object of incubating leading type 3PL were proposed.

  17. Quantification of arbuscular mycorrhizal fungal DNA in roots: how important is material preservation?

    Janoušková, Martina; Püschel, David; Hujslová, Martina; Slavíková, Renata; Jansa, Jan

    2015-04-01

    Monitoring populations of arbuscular mycorrhizal fungi (AMF) in roots is a pre-requisite for improving our understanding of AMF ecology and functioning of the symbiosis in natural conditions. Among other approaches, quantification of fungal DNA in plant tissues by quantitative real-time PCR is one of the advanced techniques with a great potential to process large numbers of samples and to deliver truly quantitative information. Its application potential would greatly increase if the samples could be preserved by drying, but little is currently known about the feasibility and reliability of fungal DNA quantification from dry plant material. We addressed this question by comparing quantification results based on dry root material to those obtained from deep-frozen roots of Medicago truncatula colonized with Rhizophagus sp. The fungal DNA was well conserved in the dry root samples with overall fungal DNA levels in the extracts comparable with those determined in extracts of frozen roots. There was, however, no correlation between the quantitative data sets obtained from the two types of material, and data from dry roots were more variable. Based on these results, we recommend dry material for qualitative screenings but advocate using frozen root materials if precise quantification of fungal DNA is required. PMID:25186648

  18. F Theory Orientifolds, M Theory Orientifolds, and Twisted Strings

    Blum, Julie D.

    1996-01-01

    Orientifolds of the type IIB superstring that descend from F theory and M theory orbifolds are studied perturbatively. One finds strong evidence that a previously ignored twisted open string is required in these models. An attempt is made to interpret the $J$ type torsion in F theory where one finds a realization of Gimon and Johnson's models which does not require these twisted strings. S-duality also provides evidence for these strings.

  19. Complexes of type C6H7(+)·L (L = N2 and CO2) studied by explicitly correlated coupled cluster theory.

    Botschwina, Peter; Oswald, Rainer

    2012-05-28

    Complexes of the benzenium ion (C(6)H(7)(+)) with N(2) or CO(2) have been studied by explicitly correlated coupled cluster theory at the CCSD(T)-F12x (x = a, b) level [T. B. Adler et al., J. Chem. Phys. 127, 221106 (2007)] and the double-hybrid density functional B2PLYP-D [T. Schwabe and S. Grimme, Phys. Chem. Chem. Phys. 9, 3397 (2007)]. Improved harmonic vibrational wavenumbers for C(6)H(7)(+) have been obtained by CCSD(T∗)-F12a calculations with the VTZ-F12 basis set. Combining them with previous B2PLYP-D anharmonic contributions we arrive at anharmonic wavenumbers which are in excellent agreement with recent experimental data from p-H(2) matrix isolation IR spectroscopy [M. Bahou et al., J. Chem. Phys. 136, 154304 (2012)]. The energetically most favourable conformer of C(6)H(7)(+)·N(2) shows a π-bonded structure similar to C(6)H(7)(+)·Rg (Rg = Ne, Ar) [P. Botschwina and R. Oswald, J. Phys. Chem. A 115, 13664 (2011)] with D(e) ≈ 870 cm(-1). For C(6)H(7)(+)·CO(2), a slightly lower energy is calculated for a conformer with the CO(2) ligand lying in the ring-plane of the C(6)H(7)(+) moiety (D(e) ≈ 1508 cm(-1)). It may be discriminated from other conformers through a strong band predicted at 1218 cm(-1), red-shifted by 21 cm(-1) from the corresponding band of free C(6)H(7)(+). PMID:22667554

  20. Complexes of type C6H7+.L (L = N2 and CO2) studied by explicitly correlated coupled cluster theory

    Botschwina, Peter; Oswald, Rainer

    2012-05-01

    Complexes of the benzenium ion (C_6 H_7^ +) with N2 or CO2 have been studied by explicitly correlated coupled cluster theory at the CCSD(T)-F12x (x = a, b) level [T. B. Adler et al., J. Chem. Phys. 127, 221106 (2007), 10.1063/1.2817618] and the double-hybrid density functional B2PLYP-D [T. Schwabe and S. Grimme, Phys. Chem. Chem. Phys. 9, 3397 (2007), 10.1039/b704725h]. Improved harmonic vibrational wavenumbers for C_6 H_7^ + have been obtained by CCSD(T*)-F12a calculations with the VTZ-F12 basis set. Combining them with previous B2PLYP-D anharmonic contributions we arrive at anharmonic wavenumbers which are in excellent agreement with recent experimental data from p-H2 matrix isolation IR spectroscopy [M. Bahou et al., J. Chem. Phys. 136, 154304 (2012), 10.1063/1.3703502]. The energetically most favourable conformer of C_6 H_7^ +.N2 shows a π-bonded structure similar to C_6 H_7^ +.Rg (Rg = Ne, Ar) [P. Botschwina and R. Oswald, J. Phys. Chem. A 115, 13664 (2011), 10.1021/jp207905t] with De ≈ 870 cm-1. For C_6 H_7^ +.CO2, a slightly lower energy is calculated for a conformer with the CO2 ligand lying in the ring-plane of the C_6 H_7^ + moiety (De ≈ 1508 cm-1). It may be discriminated from other conformers through a strong band predicted at 1218 cm-1, red-shifted by 21 cm-1 from the corresponding band of free C_6 H_7^ +.

  1. Multiple linear analysis methods for the quantification of irreversibly binding radiotracers

    Kim, Su Jin; Lee, Jae Sung; Kim, Yu Kyeong; Frost, James; Wand, Gary; McCaul, Mary E.; Lee, Dong Soo

    2008-01-01

    Gjedde–Patlak graphical analysis (GPGA) has commonly been used to quantify the net accumulations (Kin) of radioligands that bind or are taken up irreversibly. We suggest an alternative approach (MLAIR: multiple linear analysis for irreversible radiotracers) for the quantification of these types of tracers. Two multiple linear regression model equations were derived from differential equations of the two-tissue compartment model with irreversible binding. Multiple linear analysis for irreversi...

  2. Quantification, Sources, and Control of Ammonia Emissions in the Czech Republic

    Marie Skybova

    2001-01-01

    The exact quantification of ammonia (NH3) emissions is the basic presumption for the fulfilment of obligations set by the CLRTAP (Convention on Long Range Transboundary Air Pollution) Protocol which was signed by the Czech Republic in 1999. Most NH3 emissions in the Czech Republic are produced during the breeding of cattle, pigs, and poultry; therefore, determinating emission factors for these kinds of animals by studying their total number, type of breeding, and subsequent disposal of manure...

  3. Statistical theory for hydrogen bonding fluid system of A_aD_d type(II):Properties of hydrogen bonding networks

    2007-01-01

    Making use of the invariant property of the equilibrium size distribution of the hydrogen bonding clus- ters formed in hydrogen bonding system of AaDd type,the analytical expressions of the free energy in pregel and postgel regimes are obtained.Then the gel free energy and the scaling behavior of the number of hydrogen bonds in gel phase near the critical point are investigated to give the corre- sponding scaling exponents and scaling law.Meanwhile,some properties of intermolecular and in- tramolecular hydrogen bonds in the system,sol and gel phases are discussed.As a result,the explicit relationship between the number of intramolecular hydrogen bonds and hydrogen bonding degree is obtained.

  4. Statistical theory for hydrogen bonding fluid system of A_aD_d type(Ⅲ):Equation of state and fluctuations

    2007-01-01

    The equation of the state of the hydrogen bonding fluid system of AaDd type is studied by the principle of statistical mechanics. The influences of hydrogen bonds on the equation of state of the system are obtained based on the change in volume due to hydrogen bonds. Moreover,the number density fluc-tuations of both molecules and hydrogen bonds as well as their spatial correlation property are inves-tigated. Furthermore,an equation describing relation between the number density correlation function of "molecules-hydrogen bonds" and that of molecules and hydrogen bonds is derived. As application,taking the van der Waals hydrogen bonding fluid as an example,we considered the effect of hydrogen bonds on its relevant statistical properties.

  5. Fluorescence-linked Antigen Quantification (FLAQ) Assay for Fast Quantification of HIV-1 p24Gag

    Gesner, Marianne; Maiti, Mekhala; Grant, Robert; Cavrois, Marielle

    2016-01-01

    The fluorescence-linked antigen quantification (FLAQ) assay allows a fast quantification of HIV-1 p24Gag antigen. Viral supernatant are lysed and incubated with polystyrene microspheres coated with polyclonal antibodies against HIV-1 p24Gag and detector antibodies conjugated to fluorochromes (Figure 1). After washes, the fluorescence of microspheres is measured by flow cytometry and reflects the abundance of the antigen in the lysate. The speed, simplicity, and wide dynamic range of the FLAQ assay are optimum for many applications performed in HIV-1 research laboratories.

  6. Nonperturbative Formulations of Superstring Theory

    Motl, Lubos

    2001-01-01

    After a short introduction to Matrix theory, we explain how can one generalize matrix models to describe toroidal compactifications of M-theory and the heterotic vacua with 16 supercharges. This allows us, for the first time in history, to derive the conventional perturbative type IIA string theory known in the 80s within a complete and consistent nonperturbative framework, using the language of orbifold conformal field theory and conformal perturbation methods. A separate chapter is dedicate...

  7. Neural networks and graph theory

    许进; 保铮

    2002-01-01

    The relationships between artificial neural networks and graph theory are considered in detail. The applications of artificial neural networks to many difficult problems of graph theory, especially NP-complete problems, and the applications of graph theory to artificial neural networks are discussed. For example graph theory is used to study the pattern classification problem on the discrete type feedforward neural networks, and the stability analysis of feedback artificial neural networks etc.

  8. Dissipative quantum theory: Implications for quantum entanglement

    Rajagopal, A. K.; Rendell, R. W.

    2001-01-01

    Three inter-related topics are discussed here. One, the Lindblad dynamics of quantum dissipative systems; two, quantum entanglement in composite systems and its quantification based on the Tsallis entropy; and three, robustness of entanglement under dissipation. After a brief review of the Lindblad theory of quantum dissipative systems and the idea of quantum entanglement in composite quantum systems illustrated by describing the three particle systems, the behavior of entanglement under the ...

  9. Supergravity theories

    Of all supergravity theories, the maximal, i.e., N = 8 in 4-dimension or N = 1 in 11-dimension, theory should perform the unification since it owns the highest degree of symmetry. As to the N = 1 in d = 11 theory, it has been investigated how to compactify to the d = 4 theories. From the phenomenological point of view, local SUSY GUTs, i.e., N = 1 SUSY GUTs with soft breaking terms, have been studied from various angles. The structures of extended supergravity theories are less understood than those of N = 1 supergravity theories, and matter couplings in N = 2 extended supergravity theories are under investigation. The harmonic superspace was recently proposed which may be useful to investigate the quantum effects of extended supersymmetry and supergravity theories. As to the so-called Kaluza-Klein supergravity, there is another possibility. (Mori, K.)

  10. Significance of DNA quantification in testicular germ cell tumors.

    Codesal, J; Paniagua, R; Regadera, J; Fachal, C; Nistal, M

    1991-01-01

    A cytophotometric quantification of DNA in tumor cells was performed in histological sections of orchidectomy specimens from 36 men with testicular germ cell tumors (TGCT), 7 of them showing more than one tumor type. Among the variants of seminoma (classic and spermatocytic) the lowest DNA content were in spermatocytic seminoma. With respect to non-seminomatous tumors (yolk sac tumor, embryonal carcinoma, teratoma, and choriocarcinoma), choriocarcinomas showed the highest DNA content, and the lowest value was found in teratomas. No significant differences were found between the average DNA content of seminomas (all types) and non-seminomatous tumors (all types). Both embryonal carcinoma and yolk sac tumor showed similar DNA content when they were the sole tumor and when they were found associated with other tumors. In this study, except for the 4 cases of teratoma and the case of spermatocytic seminoma, all TGCT examined did not show modal values of DNA content in the diploid range. Such an elevated frequency of aneuploidism in these tumors may be helpful for their diagnosis. PMID:1666273

  11. Supersymmetric gauge theories from string theory

    This thesis presents various ways to construct four-dimensional quantum field theories from string theory. In a first part we study the generation of a supersymmetric Yang-Mills theory, coupled to an adjoint chiral superfield, from type IIB string theory on non-compact Calabi-Yau manifolds, with D-branes wrapping certain sub-cycles. Properties of the gauge theory are then mapped to the geometric structure of the Calabi-Yau space. Even if the Calabi-Yau geometry is too complicated to evaluate the geometric integrals explicitly, one can then always use matrix model perturbation theory to calculate the effective superpotential. The second part of this work covers the generation of four-dimensional super-symmetric gauge theories, carrying several important characteristic features of the standard model, from compactifications of eleven-dimensional supergravity on G2-manifolds. If the latter contain conical singularities, chiral fermions are present in the four-dimensional gauge theory, which potentially lead to anomalies. We show that, locally at each singularity, these anomalies are cancelled by the non-invariance of the classical action through a mechanism called 'anomaly inflow'. Unfortunately, no explicit metric of a compact G2-manifold is known. Here we construct families of metrics on compact weak G2-manifolds, which contain two conical singularities. Weak G2-manifolds have properties that are similar to the ones of proper G2-manifolds, and hence the explicit examples might be useful to better understand the generic situation. Finally, we reconsider the relation between eleven-dimensional supergravity and the E8 x E8-heterotic string. This is done by carefully studying the anomalies that appear if the supergravity theory is formulated on a ten-manifold times the interval. Again we find that the anomalies cancel locally at the boundaries of the interval through anomaly inflow, provided one suitably modifies the classical action. (author)

  12. Agency Theory

    Linder, Stefan; Foss, Nicolai Juul

    2015-01-01

    Agency theory studies the problems and solutions linked to delegation of tasks from principals to agents in the context of conflicting interests between the parties. Beginning from clear assumptions about rationality, contracting, and informational conditions, the theory addresses problems of ex...... agency theory to enjoy considerable scientific impact on social science; however, it has also attracted considerable criticism....

  13. Agency Theory

    Linder, Stefan; Foss, Nicolai Juul

    Agency theory studies the problems and solutions linked to delegation of tasks from principals to agents in the context of conflicting interests between the parties. Beginning from clear assumptions about rationality, contracting and informational conditions, the theory addresses problems of ex...... agency theory to enjoy considerable scientific impact on social science; however, it has also attracted considerable criticism....

  14. String theory

    This article is devoted to a nontechnical review on the present status of string theory towards an ultimate unification of all fundamental interactions including gravity. In particular, we emphasize the importance of string theory as a new theoretical framework in which the long-standing conflict between quantum theory and general relativity is resolved. (author)

  15. Packaging Theory.

    Williams, Jeffrey

    1994-01-01

    Considers the recent flood of anthologies of literary criticism and theory as exemplifications of the confluence of pedagogical concerns, economics of publishing, and other historical factors. Looks specifically at how these anthologies present theory. Cites problems with their formatting theory and proposes alternative ways of organizing theory…

  16. Theories of Urban Dynamics

    Manuel García Docampo

    2014-01-01

    This paper reviews the existing analysis framework for territorial dynamics and urban growth and proposes a taxonomy of interpretive theories as well as a critical review. Specifically, the paper aims to provide four innovations to existing knowledge in this field as follows: firstly, a clear presentation of how the data of population growth of each habitat type have appeared and their academic interpretations; secondly, a reclassification of interpretative theories into three groups: the cou...

  17. Instantons in string theory

    These proceedings from the second Caesar Lattes meeting in Rio de Janeiro 2015 are a brief introduction to how automorphic forms appear in the low energy effective action of maximally supersymmetric string theory. The explicit example of the R4-interaction of type IIB string theory in ten dimensions is discussed. Its Fourier expansion is interpreted in terms of perturbative and non-perturbative contributions to the four graviton amplitude

  18. Instantons in string theory

    Ahlén, Olof, E-mail: olof.ahlen@aei.mpg.de [Max-Planck-Institut für Gravitationsphysik (Albert-Einstein-Institut), Am Mühlenberg 1, DE-14476 Potsdam (Germany)

    2015-12-17

    These proceedings from the second Caesar Lattes meeting in Rio de Janeiro 2015 are a brief introduction to how automorphic forms appear in the low energy effective action of maximally supersymmetric string theory. The explicit example of the R{sup 4}-interaction of type IIB string theory in ten dimensions is discussed. Its Fourier expansion is interpreted in terms of perturbative and non-perturbative contributions to the four graviton amplitude.

  19. Birth of String Theory

    Itoyama, H

    2016-01-01

    This is a brief summary of an introductory lecture for students and scholars in general given by the author at Nambu Memorial Symposium which was held at Osaka City University on September 29, 2015. We review the invention of string theory by Professor Yoichiro Nambu following the discovery of the Veneziano amplitude. We also discuss Professor Nambu's proposal on string theory in the Schild gauge in 1976 which is related to the matrix model of Yang-Mills type.

  20. Aerodynamic Modeling with Heterogeneous Data Assimilation and Uncertainty Quantification Project

    National Aeronautics and Space Administration — Clear Science Corp. proposes to develop an aerodynamic modeling tool that assimilates data from different sources and facilitates uncertainty quantification. The...