WorldWideScience
1

Distinguishing between parenchymal and anastomotic leakage at duct-to-mucosa pancreatic reconstruction in pancreaticoduodenectomy  

UK PubMed Central (United Kingdom)

AIM: To distinguish anastomotic from parenchymal leakage at duct-to-mucosa reconstruction of the pancreatic remnant.METHODS: We reviewed the charts of 68 pancreaticod-uodenectomies performed...Full Text Available

2008-11-21

2

Cholangiocarcinoma associated with recurrent pyogenic cholangitis: sonographic and CT findings  

International Nuclear Information System (INIS)

Cholangiocarcinoma may be associated with recurrent pyogenic cholangitis as a complication of longstanding proliferative cholangitis in the presence of intrahepatic stones. Sonographic and CT findings of six patients with cholangiocarcinoma of the liver associated with recurrent pyogenic cholangitis are presented. The cases were among 128 patients who underwent partial resection of the liver because of recurrent pyogenic cholangitis and its complication. On sonogram the mass was depicted in four patients as an ill-defined heterogenously echogenic mass and in one patient as a bulging contour; in the remaining one case the mass was not detected. There were small or large, shadowing or non shadowing stones within the tumor in five cases. In one case, the stone was in the duct proximal to the tumor. On CT scans of four patients, the tumors were depicted as an ill-defined, irregular low attenuation masses ...

1992-01-01

3

Endoscopic snare papillectomy with biliary and pancreatic stent placement for tumors of the major duodenal papilla  

British Library Electronic Table of Contents (United Kingdom)

Background This study aimed to evaluate the feasibility, safety, and follow-up results of endoscopic papilletomy (ESP) with pancreatic and biliary duct stent placement for ampullary tumors. The therapeutic approach to benign ampullary tumors remains unsettled. The ESP procedure is a curative treatment option for benign papillary tumors, but ESP raises concerns about a relatively high risk for procedure-related complications such as pancreatitis. A pancreatic stent may protect against complications. Methods Between September 2000 and June 2008, 36 patients with ampullary tumors confined to the mucosa and no intraductal tumor growth underwent ESP. The preprocedural diagnostic tools included endoscopic ultrasound, transpapillary intraductal ultrasound, and endoscopic retrograde cholangiopancr...

2010-01-01

4

Computed tomographic findings of intrahepatic peripheral cholangiocarcinoma  

International Nuclear Information System (INIS)

Cholangiocarcinoma is synonymous with bile duct carcinoma, and can originate in a small intrahepatic bile duct (peripheral type), a major intrahepatic duct including the hepatic hills, an extrahepatic duct, or near the papilla of Vater (central type). In a sense bile duct carcinoma of the peripheral type is cholangiocarcinoma of the liver; it has the same gross configuration as hepatocellular carcinoma, resulting in difficulty to differentiate on the CT. The authors studied CT findings of 14 cases of pathologically proven peripheral type cholangiocarcinoma of the liver during the last 4 years. The results were as follows: 1. Of 14 cases, 8 were female and 6 were male, and the age ranged from 5th to 7th decades. 2. Preoperative clinical diagnosis were as follows: hepatoma 8 cases, abscess 5 cases and metastasis 1 case in order of frequency. 3. Diagnosis were confirmed by hepatic ...

1986-08-01

5

Solid-pseudopapillary tumor of the pancreas in a 13-year-old girl - case report  

International Nuclear Information System (INIS)

The solid-pseudopapillary tumor (SPT) of the pancreas is a rare type of exocrine pancreatic neoplasm. SPT predominantly affects young women and female children, and is usually discovered incidentally. This tumor is generally benign with a low incidence of malignancy. A 13-year-old girl was admitted to the hospital with a few weeks' history of mild abdominal pain and jaundice. On physical examination, there was no palpable mass. The laboratory tests showed increased SR, CRP, high bilirubin, amylase and lipase serum levels. Ultrasound imaging revealed a solid lesion in the region of the pancreatic head. On MRI, precise tumor localization in the head of the pancreas with pancreatic duct dilatation and compression of the common bile duct were visualized. Pancreaticoduodenectomy and cholecystectomy was performed with good clinical outcome. Microscopic and immunohistochemical studies ...

6

CT characterization of bile duct dilatation: Differential diagnosis of obstructive jaundice  

Energy Technology Data Exchange (ETDEWEB)

Each disease affecting the bile ducts tends to produce characteristic pattern of biliary dilatation: recurrent pyogenic cholangitis causes dilatation and straightening of the larger (central) intrahepatic ducts: clonorchiasis causes dilatation of the smaller (peripheral) intrahepatic ducts; and carcinoma along the extrahepatic ducts causes (proportional) dilatation and tortuosity of both larger and smaller intrahepatic ducts. To evaluate the specificity of the pattern and morphology of the dilated biliary tree on CT scans (CT characterization) three independent radiologists who were unifamiliar with the cases were asked to classify 62 CT scans in patients with obstructive jaundice. The case population consisted of 14 cases with recurrent pyogenic cholangitis, 18 cases with clonorchiasis and 30 cases with carcinoma along the extrahepatic ducts, which were ...

1992-07-15

7

CT characterization of bile duct dilatation: Differential diagnosis of obstructive jaundice  

International Nuclear Information System (INIS)

Each disease affecting the bile ducts tends to produce characteristic pattern of biliary dilatation: recurrent pyogenic cholangitis causes dilatation and straightening of the larger (central) intrahepatic ducts: clonorchiasis causes dilatation of the smaller (peripheral) intrahepatic ducts; and carcinoma along the extrahepatic ducts causes (proportional) dilatation and tortuosity of both larger and smaller intrahepatic ducts. To evaluate the specificity of the pattern and morphology of the dilated biliary tree on CT scans (CT characterization) three independent radiologists who were unifamiliar with the cases were asked to classify 62 CT scans in patients with obstructive jaundice. The case population consisted of 14 cases with recurrent pyogenic cholangitis, 18 cases with clonorchiasis and 30 cases with carcinoma along the extrahepatic ducts, which were ...

1992-07-01

8

CT findings of intrahepatic cholangiocarcinoma associated with hepatolithiasis  

International Nuclear Information System (INIS)

To assess the CT findings of intrahepatic cholangiocarcinoma associated with hepatolithiasis. The CT features of 26 patients with cholangiocarcinoma and hepatolithiasis were reviewed and compared with those of 23 patients with intrahepatic stones alone, acting as control subjects. CT findings were analyzed for tumor appearance and adjacency to hepatolithiasis. We studied clinical findings, noting the presence or absence of wall thickening or soft tissue attenuation within the bile duct, the luminal diameter of dilated bile duct, and the presence of periductal enhancement, and compared these with the findings for control groups. CT images of the tumor revealed a hepatic low-attenuating mass with peripheral rim enhancement(n = 14,54 %), or periductal thickening, or low-attenuating lesions in segmental dilatation of intrahepataic bile ducts(n = 12, 46 %). Most hepatic tumors were seen in areas adjacent to ...

1999-09-01

9

Laparoskopisk kolecystektomi  

DEFF Research Database (Denmark)

Forty-one patients with uncomplicated gall stone disease were laparoscopied with the object of cholecystectomy. The procedure was accomplished in 36 patients, but the operation had to be transformed to a conventional open operation in five: Fibrosis made dissection of the gall bladder hazardous in four and bleeding during the procedure made immediate laparotomy necessary in one patient, whose postoperative course was uneventful. The median operating time was 100 minutes, range was 60-250 minutes. The only operative complication was bleeding from a trocar puncture hole on the first postoperative day which stopped spontaneously in one patient. Eighteen were sent home on the first postoperative day and 12 patients on the second day. Peroperative cholangiography was performed employing the Olsen-Reddick cholangiography forceps. We have designed a special catheter, which greatly facilitates the procedure. The procedure was accomplished in 27 of 32 planned cases. Two ...

1993-01-01

10

Comparison of sclerosing cholangitis with autoimmune pancreatitis and infiltrative extrahepatic cholangiocarcinoma. Multidetector-row computed tomography findings  

International Nuclear Information System (INIS)

The aim of this study was to compare multidetector-row computed tomography (MDCT) findings between cases of sclerosing cholangitis with autoimmune pancreatitis (SC-AIP) and infiltrative extrahepatic cholangiocarcinoma (IEC). We retrospectively assessed MDCT findings from 16 IEC cases and 13 SC-AIP cases. MDCT findings were analyzed with regard to location, length, wall thickness, contour, stricture wall enhancement pattern, proximal duct diameter, and the presence of diffuse concentric thickening in the proximal duct and gallbladder wall thickness. Stricture length, stricture wall thickness, and proximal duct diameter were significantly smaller for SC-AIP than for IEC: 19.3#+-#8.7 vs. 31.8#+-#12.0 mm (P=0.004), 2.1#+-#1.3 vs. 4.1#+-#1.3 mm (P<0.001), and 9.2#+-#3.9 vs. 13.3#+-#5.0 mm (P=0.012), respectively. SC-AIP was correlated with stricture location in both the intrapancreatic and hilar hepatic ...

2010-04-01

11

SLEEPER FOR CRUSHED-STONE BALLAST  

J-STORE (Japan)

Full Text Available

2007-11-09

13

Hepatic abscess versus peripheral cholangiocarcinoma: Sonographic differentiation  

International Nuclear Information System (INIS)

To find out the sonographic findings that are useful to differentiate hepatic abscess from peripheral cholangiocarcinoma. Twenty-two hepatic abscesses and 22 peripheral cholangiocarcinomas which had been confirmed histologically were included in this study. Objective points were echo characteristics of the lesion, internal septation, presence of peripheral low echoic rim, demarcation from normal liver(well or poorly defined), posterior enhancement, multiplicity, dilatation of bile duct(obstructive or non-obstructive), intrahepatic duct stone, pleural effusion, and intra-abdominal fluid collection. Echo characteristics of the lesion were classified in-to four types. Type I; Predominantly echogenic with hypoechoic portion, type II; Echogenic without hypoechoic portion, type III; Predominantly hypoechoic with echogenic portion, type IV; Hypoechoic without echogenic portion. 1)Nine abscesses and 2 peripheral cholangiocarcinomas ...

2000-12-01

14

Complications of gallstone disease: Mirizzi syndrome, cholecystocholedochal fistula, and gallstone ileus.  

Science.gov (United States)

Gallstone is a common disease with a 10% prevalence in the United States and Western Europe. However, it is only symptomatic in 20-30% of patients, with biliary pain "colic" being the most common symptom. Complications of asymptomatic gallstone disease are generally rare, with an incidence of <1 %/yr. The most common complications of gallstone disease are acute cholecystitis, acute pancreatitis, ascending cholangitis, and gangrenous gallbladder. Less frequent complications include Mirizzi syndrome, cholecystocholedochal fistula, and gallstone ileus. Mirizzi syndrome and cholecystocholedochal fistula are two manifestations of the same process that starts with impaction of a gallstone in the gallbladder neck that results in obstruction of the bile duct, causing jaundice. The gallstone may erode into the bile duct, causing cholecystocholedochal fistula. Gallstone ileus refers to small bowel obstruction resulting from the ...

2002-02-01

15

Walled-off pancreatic necrosis  

UK PubMed Central (United Kingdom)

Walled-off pancreatic necrosis (WOPN), formerly known as pancreatic abscess is a late complication of acute pancreatitis. It can be lethal, even though it is rare. This critical review provides an overview...Full Text Available

2010-04-14

16

Autoimmune pancreatitis with atypical imaging findings that mimicked an endocrine tumor  

UK PubMed Central (United Kingdom)

Autoimmune pancreatitis (AIP) is a rare cause of recurrent acute pancreatitis or chronic pancreatitis in middle-aged patients, and is characterised by a marked infiltration of lymphocytes and plasma...Full Text Available

2010-06-21

17

Comparison between two shock wave regimens using frequencies of 60 and 90 impulses per minute for urinary stones  

UK PubMed Central (United Kingdom)

PURPOSE:Two different regimens of SWL delivery for treating urinary stones were compared.METHODS:Patients with urinary stones were randomly divided...Full Text Available

2010-10-01

18

PIXE analysis of chinese chicken-blood stone  

Energy Technology Data Exchange (ETDEWEB)

This paper reports the chemical compositions of chicken-blood stone Ji Xue Shi measured by Proton Induced X-ray Emission (PIXE). The experimental result show that for the red portion of chicken-blood stone, the concentration of Hg is as high as 20 wt%, and the concentration of S can be above 10 wt%. For the non-red portion the main chemical compositions are Al{sub 2}O{sub 3} and SiO{sub 2}. The obtained chemical compositions are close to those of kaolinite for Balin chicken-blood stone, and of pyrophyllite for Changhua chicken-blood stone, respectively. So far many Changhua chicken-blood stones and Balin chicken-blood stones were found in China, the PIXE method can be used to explore the provenance of available chicken-blood stones. (author)

1999-07-01

19

TASK 2.5.4 DEVELOPMENT OF AN ENERGY SAVINGS CALCULATOR  

Energy Technology Data Exchange (ETDEWEB)

California s major energy utilities and the California Energy Commission (CEC) are seeking to allocate capital that yields the greatest return on investment for energy infrastructure that meets any part of the need for reliable supplies of energy. The utilities are keenly interested in knowing the amount of electrical energy savings that would occur if cool roof color materials are adopted in the building market. To meet this need the Oak Ridge National Laboratory and the Lawrence Berkeley National Laboratory (LBNL) have been collaborating on a Public Interest Energy Research (PIER) project to develop an industry-consensus energy-savings calculator. The task was coordinated with an ongoing effort supported by the DOE to develop one calculator to achieve both the DOE and the EPA objectives for deployment of cool roof products. Recent emphasis on domestic building energy use has made the work a top priority by the Department of Energy s (DOE) Building Technologies Program. The Roof ...

2010-03-01

20

Parenchyma-sparing pancreatectomies for benign or border-line tumors of the pancreas  

UK PubMed Central (United Kingdom)

Standard pancreatic resections, such as pancreaticoduodenectomy, distal pancreatectomy, or total pancreatectomy, result in an important loss of normal pancreatic parenchyma and may cause impairment...Full Text Available

2010-06-15

21

[Enzymatic pancreatogenic omental bursitis].  

Science.gov (United States)

The most common causes of omental sac collections (OSC) are necrotic pancreatitis (90%) and pancreatic trauma (10%). Acute OSC is a form of local peritonitis in acute pancreatitis, subacute OSC are caused by internal pancreatic fistulas. The clinical and radiological signs, enzymatic activity of the exudate, morphological features of peritonitis were investigated. Treatment of acute OSC included conservative measures, of subacute OSC-surgical procedures. PMID:9163152

1996-01-01

22

Creation of the BioBank, Early Detection and Discovery Biomarkers  

Science.gov (United States)

Pancreatic Cancer; Head and Neck Cancer; Breast Cancer

2011-04-03

23

Treatment of Malignant Biliary Obstruction with a PTFE-Covered Self-Expandable Nitinol Stent  

Energy Technology Data Exchange (ETDEWEB)

We wanted to determine the technical and clinical efficacy of using a PTFE-covered self-expandable nitinol stent for the palliative treatment of malignant biliary obstruction. Thirty-seven patients with common bile duct strictures caused by malignant disease were treated by placing a total of 37 nitinol PTFE stents. These stents were covered with PTFE with the exception of the last 5 mm at each end; the stent had an unconstrained diameter of 10 mm and a total length of 50 80 mm. The patient survival rate and stent patency rate were calculated by performing Kaplan-Meier survival analysis. The bilirubin, serum amylase and lipase levels before and after stent placement were measured and then compared using a Wilcoxon signed-rank test. The average follow-up duration was 27.9 weeks (range: 2 81 weeks). Placement was successful in all cases. Seventy-six percent of the patients (28/37) experienced adequate palliative drainage for the remainder of their lives. There were ...

2007-10-15

24

Treatment of large proximal ureteral stones: extra corporeal shock wave lithotripsy versus semi-rigid ureteroscope with lithoclast  

UK PubMed Central (United Kingdom)

PurposeAssessment of safety and efficacy of extracorporeal shockwave lithotripsy versus semi-rigid ureteroscope with lithoclast for treatment of large proximal ureteral stones.Materials...Full Text Available

25

Stent insertion in patients with malignant biliary obstruction: problems of the Hanaro stent  

Energy Technology Data Exchange (ETDEWEB)

To investigate the problems of the Hanaro stent (Solco Intermed, Seoul, Korea) when used in the palliative treatment of patients with inoperable malignant biliary obstruction. Between January 2000 and May 2001, the treatment of 46 patients with malignant biliary obstruction involved percutaneous placement of the Hanaro stent. Five patients encountered problems during removal of the stent's introduction system. The causes of obstruction were pancreatic carcinoma (n=2), cholangiocarcinoma (n=2), and gastric carcinoma with biliary invasion (n=1). In one patient, percutaneous transhepatic cholangiography and stent insertion were performed as a one-step procedure, while the others underwent conventional percutaneous transhepatic biliary drainage for at least two days prior to stent insertion. A self-expandable Hanaro stent, 8-10 mm in deameter and 50-100 mm in lengh, and made from a strand of nitinol wire, was used in all cases. Among the five patients who ...

2002-07-01

26

Syk Tyrosine Kinase Acts as a Pancreatic Adenocarcinoma Tumor Suppressor by Regulating Cellular Growth and Invasion  

UK PubMed Central (United Kingdom)

We have identified the nonreceptor tyrosine kinase syk as a marker of differentiation/tumor suppressor in pancreatic ductal adenocarcinoma (PDAC). Syk expression is lost in poorly differentiated PDAC...Full Text Available

2009-12-01

27

Spinal Cord Stimulation for Intractable Visceral Pain due to Chronic Pancreatitis  

UK PubMed Central (United Kingdom)

Pain caused by chronic pancreatitis is medically intractable and resistant to conventional interventional or surgical treatment. We report a case of spinal cord stimulation (SCS) for intractable pain...Full Text Available

2009-08-01

28

Preoperative body composition is influenced by the stage of operable pancreatic adenocarcinoma but does not predict survival after Whipple's procedure  

UK PubMed Central (United Kingdom)

Objectives:Cachexia is common in pancreatic cancer and may have an influence on longterm survival but few studies have investigated this in patients with operable tumours. Therefore,...Full Text Available

2010-06-01

29

Pancreatic insulinoma co-existing with gastric GIST in the absence of neurofibromatosis-1  

UK PubMed Central (United Kingdom)

BackgroundGastrointestinal stromal tumours (GIST) frequently occur in patients with neurofibromatosis type 1 (NF-1). It has been reported that GIST may co-exist with pancreatic endocrine...Full Text Available

30

Pancreatic cancer: molecular pathogenesis and new therapeutic targets  

UK PubMed Central (United Kingdom)

Patients with pancreatic cancer normally present with advanced disease that is lethal and notoriously difficult to treat. Survival has not improved dramatically, despite routine use of chemotherapy...Full Text Available

2009-07-01

31

Immortalizing the Complexity of Cancer Metastasis Genetic Features of Lethal Metastatic Pancreatic Cancer Obtained from Rapid Autopsy  

UK PubMed Central (United Kingdom)

The virtual lack of well-characterized metastatic pancreatic cancer tissues for study has limited systematic studies of the metastatic process of this deadly disease. To address this important...Full Text Available

2005-05-01

32

Identification of Achaete-scute complex-like 1 (ASCL1) target genes and evaluation of DKK1 and TPH1 expression in pancreatic endocrine tumours  

UK PubMed Central (United Kingdom)

BackgroundASCL1 role in pancreatic endocrine tumourigenesis has not been established. Recently it was suggested that ASCL1 negatively controls expression of the...Full Text Available

33

Hyperbilirubinemia in Inflammatory Pancreatic Disease: Natural History and Management  

UK PubMed Central (United Kingdom)

Of 868 patients admitted with pancreatitis between 1971 and 1976, coexisting hyperbilirubinemia was noted in 125 (14%). The patient population was primarily composed of alcoholics (84%) with chronic...Full Text Available

1978-11-01

34

Haplotype of N-Acetyltransferase 1 and 2 and Risk of Pancreatic Cancer  

UK PubMed Central (United Kingdom)

We examined the association between N-acetyltransferase 1 and 2 (NAT1 and NAT2) haplotype and risk of pancreatic cancer by genotyping eight...Full Text Available

2007-11-01

35

Genetically-engineered mouse models for pancreatic cancer: Advances and current limitations  

UK PubMed Central (United Kingdom)

Recently, there has been significant progress in the development of genetically-engineered mouse (GEM) models. By introducing genetic alterations and/or signaling alterations of human pancreatic cancer...Full Text Available

2011-05-10

36

Diagnosis and Management of Cystic Lesions of the Pancreas  

UK PubMed Central (United Kingdom)

Pancreatic cysts are challenging lesions to diagnose and to treat. Determining which of the five most common diagnoses—pancreatic pseudocyst, serous cystic neoplasm (SCN), solid pseudopapillary...Full Text Available

2011-01-01

37

Clinical effects of laparotomy with perioperative continuous peritoneal lavage and postoperative hemofiltration in patients with severe acute pancreatitis  

UK PubMed Central (United Kingdom)

BackgroundThe elevated serum and peritoneal cytokine concentrations responsible for the systemic response syndrome (SIRS) and multiorgan failure in patients with severe acute pancreatitis...Full Text Available

38

Clinical Implications of Immunohistochemically Demonstrated Lymph Node Micrometastasis in Resectable Pancreatic Cancer  

UK PubMed Central (United Kingdom)

The purpose of this study was to determine the clinical significance of nodal micrometastasis detected by immunohistochemistry in patients that had undergone curative surgery for pancreatic cancer....Full Text Available

2011-07-01

39

CDDO-Me: A Novel Synthetic Triterpenoid for the Treatment of Pancreatic Cancer  

UK PubMed Central (United Kingdom)

Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal human malignancy with dismal prognosis and few effective therapeutic options. Novel agents that are safe and effective are urgently...Full Text Available

2010-12-01

40

A Spindle Cell Predominant Pancreatic Solid-pseudopapillary Tumor  

UK PubMed Central (United Kingdom)

A hitherto unrecognized variant of solid-pseudopapillary tumor (SPT) of the pancreas is reported. The tumor presented in the pancreatic tail of a 44-year-old female patient. It was a well-defined, solid...Full Text Available

2008-08-30

41

Successful treatment of pediatric IgG4 related systemic disease with mycophenolate mofetil: case report and a review of the pediatric autoimmune pancreatitis literature  

UK PubMed Central (United Kingdom)

Autoimmune pancreatitis is frequently associated with elevated serum and tissue IgG4 levels in the adult population, but there are few reports of pediatric autoimmune pancreatitis, and even fewer reports...Full Text Available

43

Two stents insertion via single tract for treatment of hepatic hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Objective: To evaluate the feasibility and clinical application of two stents insertion via single tract for treatment of hepatic hilar cholangiocarcinoma. Methods: Eighteen patients with hepatic hilar cholangiocarcinoma who had left and right bile duct obstruction were treated with stents insertion via right bile duct puncturing routeway. These two stents were implanted between right and left bile duct, and between right bile duct and common bile duct. Results: Eighteen patients obtained successful two stents placement by right bile duct puncturing tract and succeeded with internal drainage for all biliary tree jaundice subsided distinctly. Conclusions: The technique of two stents insertion via single tract could predigest interventional drainage procedure of high bile duct obstruction, reduce operation trauma, shorten handling time and ...

2003-12-01

44

Sonography, Computed Tomography and ERCP in the diagnosis of focal exocrine pancreatic disease  

International Nuclear Information System (INIS)

In spite of the improved imaging techniques currently available, mortality for pancreatic cancer is still high, and pancreatics is often diagnosed only in its advanced stages. The authors investigated the value of different imaging techniques - i.e., US, CT, and ERCP - for an early diagnosis, when a more effective (curative?) treatment can be suggested. Fifty-six cases of pancreatic cancer and 36 cases of chronic pancreatitis were evaluated. The results indicate that ERCP, with the help of statistical methods, is superior to US and CT not only in evaluating early neoplastic or inflammatory lesions, but also for their differential diagnosis. In the letter case, ERCP can sometimes be used as a valid alternative to fine-needle aspiration biopsy.

1991-01-01

45

Citrat og nyresten  

DEFF Research Database (Denmark)

Citrate is an important naturally occurring inhibitor of calcium stone formation in urine. Urinary citrate excretion was examined in 43 consecutive patients with recurrent idiopathic calcium nephrolithiasis and in 50 normal controls by a specific enzymatic technique. Hypocitraturia (<1.6 mmol/24h) was found in 14 (33%) stone formers compared to 6 (12%) normal controls (p = 0.03). Citrate excretion expressed as citrate-creatinine ratio in 24 hour urine samples was significantly lower in the stone formers than in the healthy controls (p = 0.03), and significantly lower in healthy men, compared to healthy females (p = 0.006). There was a great variability in urinary citrate levels in both groups, and a considerable overlap in the urinary citrate excretion between normal subjects and stone formers. Factors other than urinary citrate excretion must therefore be of importance in the pathophysiology of ...

1993-01-01

46

Weathering behaviour and construction suitability of dimension stones from the Drei Gleichen area (Thuringia, Germany)  

British Library Electronic Table of Contents (United Kingdom)

The construction suitability of a dimension stone depends on its weathering properties along with the petrology and the petrophysical properties. The aim of this study was to evaluate the suitability of the dimension stones from the ?Drei Gleichen? area for construction and replacement purposes. In total, six sandstones (Ingersleben, Wachsenburg, Hindfelden, Seeberg, R?hnberg, Gleichenberg; Upper Triassic) as well as two carbonates (Wachsenburg sinter; Quaternary, Wandersleben dolomite; Middle Triassic) were analysed. The results from our laboratory and on-site studies of the dimension stones show that rocks from the same stratigraphic layer, like the sandstones from the upper Triassic, can show major differences in their petrophysical and weathering properties. These differences are attri...

2011-01-01

47

Percutaneous nephrolithotomy for staghorn kidney stones in elderly patients  

British Library Electronic Table of Contents (United Kingdom)

Purpose We retrospectively analyzed the results of percutaneous nephrolithotomy operations for treatment of staghorn kidney stone disease in elderly patients and compared surgical parameters and outcomes with a control group of young adult patients. Patients and method Between 2002 and 2010, 300 consecutive patients underwent percutaneous nephrolithotomy operation for treatment of staghorn kidney stone disease. Forty-five of the patients were older than 65?years and considered to be in elderly group. Thirty-seven of the patients were between the ages 18 and 36?years and considered to be the control group. Surgical parameters and outcomes were compared between groups. Results There were no significant differences between groups for stone area, operation time, difference in hemoglobin levels...

2011-01-01

48

Laboratory Description of Harbor Idealized Tests. Volume 1 ...  

Science.gov (United States)

... modules 2 and 3, 45 ft from each end) in a ... The toe of the stone revetment was 2 ft out from the ... in parentheses are for the current meters in layout 2. ...

1993-03-01

49

Gallbladder function and dynamics of bile flow in asymptomatic gallstone disease  

UK PubMed Central (United Kingdom)

AIM: To investigate the effects of gallbladder stones on motor functions of the gallbladder and the dynamics of bile flow in asymptomatic gallstone disease.METHODS: Quantitative hepatobiliary...Full Text Available

2009-06-14

50

Final Environmental Baseline Survey Report For The Plum Brook ...  

Science.gov (United States)

9-foot 9-inch blocks of concrete with asphaltic-filled expansion joints. The concrete was placed on 4 to 6 inches of gravel or #4 stone. ...

51

Bladder outlet obstruction in male cystinuria mice  

UK PubMed Central (United Kingdom)

BackgroundCystinuria is the most common inherited cause of urinary tract stones in children. It can lead to obstructive uropathy, which is a major cause of renal...Full Text Available

2010-03-01

52

AN ANNOTATED BIBLIOGRAPHY OF ADULT LITERACY ...  

Science.gov (United States)

... Stone, CR & Grover, CC Practice Readers ... Tolbert, M., Withers, S. & Watkins, HT, Good Workers All State Department of Education, Columbia, South ...

1954-09-30

53

Patent arterial duct  

UK PubMed Central (United Kingdom)

Patent arterial duct (PAD) is a congenital heart abnormality defined as persistent patency in term infants older than three months. Isolated PAD is found in around 1 in 2000 full term infants. A higher...Full Text Available

54

Immune-mediated bile duct injury: The case of primary biliary cirrhosis  

UK PubMed Central (United Kingdom)

Autoimmune cholangitis would be the appropriate name to define the immune-mediated bile duct injury following the breakdown of tolerance to mitochondrial proteins and the appearance of serum autoantibodies...Full Text Available

2010-10-15

55

Effect of neonatal exposure to estrogenic compounds on development of the excurrent ducts of the rat testis through puberty to adulthood.  

UK PubMed Central (United Kingdom)

Neonatal exposure to diethylstilbestrol (DES) can alter the structure of the testicular excurrent ducts in rats. We characterized these changes according to dose and time posttreatment and established...Full Text Available

1999-05-01

56

Study of cytomorphology of solid pseudopapillary tumor of pancreas and its differential diagnosis  

UK PubMed Central (United Kingdom)

Background:Solid pseudopapillary tumor is a rare pancreatic neoplasm with uncertain to low malignant potential. This is an uncommon neoplasm with many pseudonyms, occurring...Full Text Available

2010-10-01

57

Impingement-Film Heat Transfer Investigation.  

Science.gov (United States)

... Abstract : This report covers the investigation of an impingement-film cooling system designed to cool the exhaust ducts of turboshaft engines ...

1973-12-01

58

Optimum aspect ratio for heat transfer enhancement in curved rectangular channels  

Science.gov (United States)

Enhanced heat transfer in curved rectangular channels depends on at least two geometric factors, the radius of curvature of the duct and the aspect ratio, which is the width/depth ratio of the duct. In this work, an expression for optimum aspect ratio is derived mathematically from a correlation that includes both aspect ratio and bend curvature parameters. Enhancement factors are developed that show optimal, near-optimal, and nonoptimal aspect ratios for curved rectangular ducts. Predicted enhancements are within 25% of published literature results for individual designs, two of which show heat transfer enhancement of 200% over that of a straight duct with turbulent flow. The theoretical maximum enhancement is shown to be about 480% over a straight-duct, turbulent-flow situation. This is not achievable in practice, but near-optimal solutions are achievable, yielding enhancements on ...

59

Calculation of the view factors for radiant heat exchange in a new volumetric receiver with tapered ducts  

Energy Technology Data Exchange (ETDEWEB)

The need to increase efficiency of volumetric receivers for use in solar power plants by reducing reradiation losses and increasing the ``volumetric effect`` has promoted the idea of a receiver with tapered ducts. These seems to be very promising since higher efficiency and considerable saving of material can be achieved, as compared to conventional receivers perforated with ducts of constant cross-section. A finite element program is being developed to calculate stationary heat transfer in the tapered ducts by free and forced convection in the gas flow, conduction in walls and in the gas, and solar and thermal radiation. Gas and wall temperatures are considered to be varying only in the flow direction. In order to perform the highly nonlinear calculations of radiative exchange, the exact knowledge of the view factors is necessary. The aim of the present work is to evaluate analytically the view factors in tapered ...

1995-02-01

60

MRI of the pancreas: Radiological-pathological correlation; MRT des Pankreas: Radiologisch-pathologische Korrelation  

Energy Technology Data Exchange (ETDEWEB)

The typical MRI features of the most common pancreatic diseases, such as pancreatitis and adenocarcinoma of the pancreas, have been established. However, even in these common pancreatic disorders, MRI correlation with the underlying pathology is limited for clinical reasons. We emphasize MR-pathological correlation of inflammatory and neoplastic pancreatic changes, including pancreatitis, adenocarcinoma, acinar cell carcinoma, rare cystic and solid pancreatic neoplasms, and islet cell tumors. By highlighting the correlation of key pathological features with MR findings, a better understanding of the MR appearance of pancreatic pathology can be provided. In addition, MRI may prove a powerful tool in detection and characterization of pancreatic tumors. (orig.) [Deutsch] Das MR-tomographische Erscheinungsbild von ...

1996-05-01

61

Hemodynamic characterization of chronic bile duct-ligated rats: effect of pentobarbital sodium  

International Nuclear Information System (INIS)

Systemic and splanchnic hemodynamics of the chronic bile duct-ligated rat were characterized by radioactive microspheres. Conscious and pentobarbital sodium-anesthetized, bile duct-ligated and sham-operated rats had cardiac output and regional organ blood flows determined. The conscious bile duct-ligated rat compared with the sham-operated showed a hyperdynamic circulation with an increased cardiac output and portal tributary blood flow. Pentobarbital sodium anesthesia induced marked hemodynamic changes in both sham-operated and bile duct-ligated rats. The latter group was especially sensitive to its effects; thus, comparison of cardiac output and portal tributary blood flow between anesthetized bile duct-ligated and sham-operated rats showed no significant differences. The authors conclude that the rat with cirrhosis due to chronic bile duct ligation is an ...

62

Augmented heat transfer in a rectangular duct with angled ribs  

Energy Technology Data Exchange (ETDEWEB)

Heat transfer augmentation in a rib-roughened duct is affected by the rib configurations, such as rib height, angle of attack, shape, rib to rib pitch, and aspect ratio of a duct. These have been the main subjects in studying the average heat transfer and the friction loss of the fully developed flow. Investigating distributions of local heat transfer coefficients and flow patterns in a duct with the rib turbulators is necessary to find the characteristics of heat transfer augmentation and to decide the optimal configurations of ribs. In the present study the numerical analyses and the mass transfer experiments are performed to understand the flow through a rib roughened duct and the heat transfer characteristics with various angles of attack of ribs. A pair of counter-rotating secondary flow in a duct has a main effect on the lateral distributions of local mass transfer ...

1998-04-01

63

Molecular cloning, genomic organization, and chromosomal localization of the human pancreatitis-associated protein (PAP) gene  

Energy Technology Data Exchange (ETDEWEB)

Pancreatitis-associated protein (PAP) is a secretory pancreatic protein present in small amounts in normal pancreas and overexpressed during the acute phase of pancreatitis. In this paper, the authors describe the cloning, characterization, and chromosomal mapping of the human PAP gene. The gene spans 2748 bp and contains six exons interrupted by five introns. The gene has a typical promoter containing the sequences TATAAA and CCAAT 28 and 52 bp upstream of the cap site, respectively. They found striking similarities in genomic organization as well as in the promoter sequences between the human and rat PAP genes. The human PAP gene was mapped to chromosome 2p12 using rodent-human hybrid cells and in situ chromosomal hybridization. This localization coincides with that of the reg/lithostathine gene, which encodes a pancreatic secretory protein structurally related to PAP, suggesting that both genes ...

1994-01-01

64

Variants in Inflammation Genes and the Risk of Biliary Tract Cancers and Stones: A Population-based Study in China  

UK PubMed Central (United Kingdom)

To evaluate the role of chronic inflammation in the development of gallstones and biliary tract cancer, we examined the risk associated with 62 single nucleotide polymorphisms (SNPs), including...Full Text Available

2008-08-01

65

Reproductive factors and risks of biliary tract cancers and stones: a population-based study in Shanghai, China  

UK PubMed Central (United Kingdom)

Background:Parity has been linked to gallbladder cancer and gallstones, but the effects of other reproductive factors are less clear.Methods:We examined...Full Text Available

2010-03-30

66

Problematic renal calculi presenting during pregnancy.  

UK PubMed Central (United Kingdom)

Urinary tract calculi presenting during pregnancy are rare, with less than 0.1% of pregnancies being associated with stones, the vast majority being asymptomatic and a chance finding. We outline six...Full Text Available

1996-03-01

67

Print sec333photoindex (256 pages)  

Science.gov (United States)

Electro-Magnet. Antenna Panels Types Simulated Hail Stone Damage A.Panel ...... X-Band Klystron Electro Magnet. 11. I I. 333-6104 AcBc. 333-6105 Color ...

68

Linear and Nonlinear Effects of Habitat Structure on Composition and Abundance in the Macroinvertebrate Community of a ...  

Science.gov (United States)

... describe the relationship (Peake and Quinn, 1993). The power model was considered best if the R2 from this ... when stone abundance was low (Fig. 2). The power model best described the nonlinear relations...

69

Pathophysiology of incomplete renal tubular acidosis in recurrent renal stone formers: evidence of disturbed calcium, bone and citrate metabolism  

DEFF Research Database (Denmark)

Urinary acidification, bone metabolism and urinary excretion of calcium and citrate were evaluated in 10 recurrent stone formers with incomplete renal tubular acidosis (iRTA), 10 recurrent stone formers with normal urinary acidification (NUA) and 10 normal controls (NC). Patients with iRTA had lower plasma standard bicarbonate after fasting (P <0.01) and lower urinary excretion of titratable acid (P <0.05) and citrate (P <0.01) compared with NUA patients and NC, and higher urinary excretion of ammonia (P <0.05) compared with NC (P <0.05). Hypercalciuria was found in 6 of 10 patients with iRTA compared with 3 of 10 with NUA, and 0 of 10 NC. The citrate/calcium ratio in urine was significantly reduced in iRTA compared with the value in NUA (P <0.01), and in NUA compared with NC (P <0.05). Biochemical markers of bone formation (serum osteocalcin) and bone resorption (urinary hydroxyproline) were significantly increased in iRTA ...

1993-01-01

70

Structural analysis of experimental carbide fueled driver assmbly flow duct for testing in the FFTF  

International Nuclear Information System (INIS)

Mixed carbide fueled driver assembly experiments will be tested in FFTF fuel driver positions as part of the National Advanced Fuel Program. The design of the experiment flow ducts must assure conformance to FFTF functional requirements in addition to service as a test vehicle for the carbide fuel irradiations. Test goals of damage fluence burnup, and fluence to burnup ratio exceed those of the standard oxide fueled drivers. As a consequence, the 20% cold worked type 316 stainless steel material of construction will experience significant irradiation induced creep and swelling. Additionally, the flow duct design must withstand the enhanced thermal transients produced by the action of carbide fuel during reactor scrams. A major FFTF functional requirement is that adjacent flow ducts do not touch each other except at the load pads. This requires a realistic analysis of the creep and swelling deformation of the flow ...

71

Curative resection of a huge malignant pancreatic endocrine tumor by pancreatoduodenectomy with portal and superior mesenteric vein resection and reconstruction using the right ovarian vein: Report of a case  

British Library Electronic Table of Contents (United Kingdom)

Nonfunctioning pancreatic endocrine tumors (PETs) are rare and generally asymptomatic. A 68-year-old woman who had refused treatment for a pancreatic mass, revealed by ultrasonography to be 55 mm in diameter, was referred to us again 29 months later with jaundice. Investigations showed an 82-mm tumor in the head of pancreas, exposed from the papilla of Vater to the duodenal lumen. After biliary decompression and drainage, we performed pancreatoduodenectomy with resection of the portal vein and superior mesenteric vein, followed by reconstruction using a cylindrically customized autologous graft harvested from the right ovarian vein. The tumor was resected curatively. Microscopically, it consisted of trabecular and ribbon-like arrangement of neoplastic cells. Immunohistochemical staining wa...

2011-01-01

72

Thermally developing flow in curved square ducts with internal fins  

Energy Technology Data Exchange (ETDEWEB)

The laminar incompressible hydrodynamically fully developed and thermally developing flow is studied in a curved square duct with four longitudinal fins. The duct is successively subjected to constant wall temperature, to circumferentially uniform temperature and axially linearly or exponentially varying temperature. The local and fully developed Nusselt numbers are examined for various values of the Dean number and it is found that the heat transfer rate increases for high fins. The parameters that affect the entry length are studied and the fluctuations of the local Nu that appear in the entrance region are investigated. Temperature contour plots are presented for the visualization of the temperature field and functional relations for the Nusselt number are proposed in terms of the Dean and Prandtl numbers. (orig.)

2005-11-01

73

Optimum profiles for asymmetrical longitudinal fins in annular ducts  

Energy Technology Data Exchange (ETDEWEB)

In the present work the geometry of annular ducts with asymmetrical longitudinal fins is optimized in order to enhance the heat transfer under laminar coolant flow conditions. The heat transferred is also maximized for a given amount of material or hydraulic resistance. Polynomial profiles are assigned to the two lateral fin surfaces. Velocity and temperature distributions on the annular duct cross section are determined with the help of a finite-element model. A global heat transfer coefficient and an equivalent Nusselt number are then calculated. Lastly, optimum asymmetrical fins obtained by means of a genetic algorithm are shown for different situations and their performance is compared with those of optimum symmetrical fins.

2000-04-01

74

Fundamental investigation of duct/ESP phenomena. Final report  

Energy Technology Data Exchange (ETDEWEB)

Radian Corporation was contracted to investigate duct injection and ESP phenomena in a 1.7 MW pilot plant constructed for this test program. This study was an attempt to resolve problems found in previous studies and answer remaining questions for the technology using an approach which concentrates on the fundamental mechanisms of the process. The goal of the study was to obtain a better understanding of the basic physical and chemical phenomena that control: (1) the desulfurization of flue gas by calcium-based reagent, and (2) the coupling of an existing ESP particulate collection device to the duct injection process. Process economics are being studied by others. (VC)

1991-10-21

75

Fundamental investigation of duct/ESP phenomena  

Energy Technology Data Exchange (ETDEWEB)

Radian Corporation was contracted to investigate duct injection and ESP phenomena in a 1.7 MW pilot plant constructed for this test program. This study was an attempt to resolve problems found in previous studies and answer remaining questions for the technology using an approach which concentrates on the fundamental mechanisms of the process. The goal of the study was to obtain a better understanding of the basic physical and chemical phenomena that control: (1) the desulfurization of flue gas by calcium-based reagent, and (2) the coupling of an existing ESP particulate collection device to the duct injection process. Process economics are being studied by others. (VC)

1991-10-21

76

Analysis of laminar flow and heat transfer in the entrance region of an internally finned concentric circular annular duct  

Energy Technology Data Exchange (ETDEWEB)

The concentric circular annular duct is a common geometry in many fluid flow and heat transfer devices. For the purpose of heat transfer augmentation, fins are often employed in the annular region, and such finned ducts find wide application in compact heat exchangers (5, 6). The analysis of flow and heat transfer in this geometry is, therefore, quite important from an engineering standpoint. For fully developed conditions, the problem has already been analyzed (7-10). However, no results are available for the developing flow in the entrance region. It is with this latter problem that the present paper is concerned.

1987-05-01

77

Free air flows for the removal of pollutants from car parks. Air-conditioning systems without sheet-metal ducts as an alternative to transverse ventilation with sheet-metal ducts. Pt. 2. Freie Luftstroemungen entsorgen Parkraeume. RLT-Anlagen ohne Blechkanaele als Alternative zur Querlueftung mit Blechkanaelen. T. 2  

Energy Technology Data Exchange (ETDEWEB)

In parking areas of large extent, the removal of engine exhaust gases, especially of their CO gas components with ventilation plant is mainly done by transverse ventilation over short paths. By their presence, the ventilation ducts required for this purpose often reduce the value of the parking space by restrictions with a consequent reduction of their acceptance by the users. Longitudinal ventilation without ducts can be a remedy in such cases. Depending on the required room air quality in the zones of highest loading, the volume flows with longitudinal removal are no greater than with conventional transverse ventilation. This article is concerned with the different methods of operation of the two systems. (orig./BWI)

1994-04-01

78

Cowper's syringocele: an analysis of 15 consecutive cases.  

UK PubMed Central (United Kingdom)

Cystic dilatation of Cowper's gland ducts (Cowper's syringocele) is uncommon in children and is frequently asymptomatic, but it may cause urinary infection, haematuria, dysuria, and obstructive voiding...Full Text Available

1996-07-01

79

Whipple Procedure for Pancreatic Cancer  

Medline Plus

... be able to watch the many intricate steps Dr. Richard Alexander must accomplish to remove the cancer. ... door to informed medical care. Now let's join Dr. Richard Alexander at the University of Maryland Medical ...

80

The effects of zinc deficiency on pancreatic carboxypeptidase activity and protein digestion and absorption in the rat  

UK PubMed Central (United Kingdom)

1. Proteolytic enzyme activities were examined in the pancreas of zinc-deficient and control rats. 2. No change was detected in trypsin-plus-chymotrypsin activity. 3. Carboxypeptidase activity was...Full Text Available

1967-03-01

81

Surgical Management of Solid-Pseudopapillary Neoplasms of the Pancreas (Franz or Hamoudi Tumors): A Large Single-Institutional Series  

UK PubMed Central (United Kingdom)

BACKGROUNDSolid-pseudopapillary neoplasms (SPNs) are rare pancreatic tumors with malignant potential. Clinicopathologic characteristics and outcomes of patients with...Full Text Available

2009-05-01

82

Solitary Fibrous Tumor of the Pancreas: Imaging Findings  

UK PubMed Central (United Kingdom)

We report here a case of a pathologically proven solitary fibrous tumor of the pancreas. A 54-year-old man was referred to our hospital for further evaluation of a pancreatic mass that was found incidentally....Full Text Available

2008-07-01

83

Pathological differential diagnosis of solid-pseudopapillary neoplasm and endocrine tumors of the pancreas  

UK PubMed Central (United Kingdom)

AIM: To investigate differential points of solid-pseudopapillary neoplasm (SPN) of the pancreas and pancreatic endocrine tumor (PET).METHODS: Ten cases of SPN and fourteen cases of PET were studied...Full Text Available

2010-02-28

84

Nuclear-Cytoplasmic Shuttling of Menin Regulates Nuclear Translocation of ?-Catenin?  

UK PubMed Central (United Kingdom)

Menin, which is encoded by the multiple endocrine neoplasia type 1 (MEN1) gene, is a tumor suppressor and transcriptional regulator. Menin controls proliferation and apoptosis of cells, especially pancreatic...Full Text Available

2009-10-01

85

Multifocal papillary-cystic neoplasm of the pancreas.  

UK PubMed Central (United Kingdom)

This case report describes the second known instance of a multifocal capillary pancreatic neoplasm. Both cases occurred in young African American females. A less-than-total pancreatectomy was performed...Full Text Available

2003-12-01

86

Middle segment pancreatectomy can be safely incorporated into a pancreatic surgeon's clinical practice1  

UK PubMed Central (United Kingdom)

Middle segment pancreatectomy (MSP) is a new operation where the advantages of parenchymal preservation are counterbalanced by a high postoperative complication rate and unease among surgeons with adopting...Full Text Available

2008-12-01

87

Insulin and Glucagon Regulate Pancreatic ?-Cell Proliferation  

UK PubMed Central (United Kingdom)

Type 2 diabetes mellitus (T2DM) results from insulin resistance and β-cell dysfunction, in the setting of hyperglucagonemia. Glucagon is a 29 amino acid peptide hormone, which is secreted from...Full Text Available

88

Influence of microenvironment on engraftment of transplanted ?-cells  

UK PubMed Central (United Kingdom)

Pancreatic islet transplantation into the liver provides a possibility to treat selected patients with brittle type 1 diabetes mellitus. However, massive early β-cell death increases the number...Full Text Available

2011-02-01

89

Bilateral Pneumothorax and Subcutaneous Emphysema following Endoscopic Retrograde Cholangiopancreatography: A Rare Complication  

UK PubMed Central (United Kingdom)

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a widely used diagnostic and therapeutic modality in the management of biliary and pancreatic disease. Some of the complications of the procedure,...Full Text Available

2010-01-01

90

An unusual presentation of pancreatic pseudocyst mimicking cystic neoplasm of the pancreas: a case report  

UK PubMed Central (United Kingdom)

In spite of their rarity, cystic neoplasms of the pancreas are characterized by existing or potential malignancy that cannot be ignored during decisive process with regard to the choice of treatment....Full Text Available

91

A homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, ? cell hyperplasia, and islet cell tumor  

UK PubMed Central (United Kingdom)

ObjectiveThe goal of the study was to investigate the genetic and molecular basis of a novel syndrome of marked hyperglucagonemia and pancreatic α cell hyperplasia...Full Text Available

2009-11-01

92

Percutaneous treatment of thrombosed native arteriovenous dialysis fistula insufficiency: efficacy of mechanical thrombectomy with using the stone basket  

Energy Technology Data Exchange (ETDEWEB)

We wanted to evaluate the procedural success after percutaneous treatment of thrombosed native arteriovenous dialysis fistula insufficiency and the efficacy of performing mechanical thrombectomy with using the stone basket. From March 2004 to June 2005, 36 thrombosed native hemodialysis access shunts in the upper limbs (brachiocephalic fistulas: 16 and radiocephalic fistulas: 20) were percutaneously treated in 30 patients. Declotting procedures were performed with using urokinase (100,00-200,000 unit) and manual catheter-directed thrombo-aspiration in all the patients. Angioplasty (6 mm in diameter and 4 cm in length) was performed at the identified area of the stenosis and /or with maceration of the thrombus. In 14 cases with massive thrombosis that was refractory to the above mentioned declotting procedures, mechanical thrombectomy with using a Wittich nitinol stone basket (Cook, Bloomington, IN) was performed. Data regarding the procedural ...

2006-06-15

93

Modified nasolacrimal duct stenting  

International Nuclear Information System (INIS)

Objective: Traditional nasolacrimal duct stenting possesses some shortcoming including difficulty of pulling ball head guide wire from the nasal cavity with turbinate hypertrophy and nasal septal deviation. The new method of nose-oral tube track establishment can overcome the forementioned and increase the successful rate. Methods: 5 F catheter and arterial sheath were modified to be nasolacrimal duct stent delivery device respectively. Antegrade dacryocystography was taken firstly to display the obstructed site and followed by the modified protocol of inserting the guide wire through nasolacrimal duct and nasal cavity, and establishing the stent delivery track for retrograde stent placement. Results: 5 epiphora patients with failure implantation by traditional method were all succeeded through the modified stenting (100%). During 6-mouth follow-up, no serious complications and reocclusion occurred. Conclusion: The ...

2008-06-01

94

Reliability analysis of the downstream face of a rockfill dam. Introductory work  

Energy Technology Data Exchange (ETDEWEB)

Reliability analysis is now being used to a large extent for several civil engineering structures. Such analysis has not been used for rockfill dams, the most common dams in Norway. Following work on reliability analysis for breakwaters, reliability analysis was then used to investigate the ability of the stone material on the upstream face of a rockfill dam to withstand wind generated waves. An attempt is made to follow up this work by including discharge overtopping on a rockfill dam in a reliability analysis. This report primarily goes through previous work on the required weight of protective stones on the downstream face of the dam for specified discharges over the dam and also deals with the probability formulation of extreme floods. A failure function with partial coefficients is formulated. But for reasons of economy the calibration of the partial coefficients remains for a next phase of the project. 14 refs., 17 figs.

1995-02-01

95

Multislice helical CT in the diagnosis of hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Objective: To investigate the value ofMSCT in observing the direct findings of hilar cholangiocarcinoma1Methods Multislice helical CT studies were performed on the upper abdomen in 19 consecutive patientswith painless jaundice1 Precontrast and dynamic contrast enhanced (25 s phase and 60 s phase) scanswere conducted, and 3D imageswere reconstructed using enhanced raw data in 15 cases1 The direct CT findings of hilar cholangiocarcinoma were studied by three radiologists respectively in a 32scale strategy1 The morphological features and extension of bile duct involvement by hilar cholangiocarcinoma were analyzed1 All the 19 caseswere pathologically p roved as hilar cholangiocarcinoma by surgery (15 cases) and ERCP ( 4 cases) 1 Results The direct findings and extension of hilar cholangiocarcinoma could be demonstrated in 14 out of 15 3D reconstruction images, 8 out of 19 in 25 s phase, and 7 out of 19 in 60 s phase of contrast enhancement scans, respectively ( P < ...

2005-11-01

96

Experimental validation of large eddy simulations of flow and heat transfer in a stationary ribbed duct  

International Nuclear Information System (INIS)

Accurate prediction of ribbed duct flow and heat transfer is of importance to the gas turbine industry. The present study comprehensively validates the use of large eddy simulations (LES) for predicting flow and heat transfer with measured flowfield data in a stationary duct with 90"o ribs and elucidates on the detailed physics encountered in the developing flow region, the fully developed region, and the 180"o bend region. Among the major flow features predicted with accuracy are flow transition at the entrance of the duct; the distribution of mean and turbulent quantities in the developing, fully developed, and 180"o bend; the development of secondary flows in the duct cross-section and the 180"o bend; and friction and heat transfer augmentation. At the duct inlet, both the computations and experiments show that the peak turbulence intensities reach values as high as 40% in the ...

2006-04-01

97

Safety designs for sludge ducts in brown coal briquetting plants  

Energy Technology Data Exchange (ETDEWEB)

Studies technological safety of installing a water spray pressure vessel between electrostatic dedusters and coal sludge ducts. These sprays are in use elsewhere for steam generator ash removal. Dust ignition and explosion tests were carried out to examine flame and pressure wave propagation through the vessel into ducts. Water jet diameter, amount of water sprayed and coal dust removed were varied. Pressure waves exceeded 250 Pa. Test results show the vessel to be suitable for installation in briquetting plants due to its flame and explosion barrier effect and extermination of smoldering dust fires. The only disadvantage of the vessel is seen as its water and electric power consumption; about 8/sup 3//h of water and 1.5 kW/h of power per vessel serving dedusters of a 2,200 m/sup 2/ rotary brown coal dryer.

1987-06-01

98

Transforming growth factor-b induces nerve growth factor expression in pancreatic stellate cells by activation of the ALK-5 pathway  

British Library Electronic Table of Contents (United Kingdom)

Nerve growth factor (NGF), a survival factor for neurons enforces pain by sensitizing nociceptors. Also in the pancreas, NGF was associated with pain and it can stimulate the proliferation of pancreatic cancer cells. Hepatic stellate cells (HSC) respond to NGF with apoptosis. Transforming growth factor (TGF)-b, one of the strongest pro-fibrogenic activators of pancreatic stellate cells (PSC) induced NGF and its two receptors in an immortalized human cell line (ihPSC) and primary rat PSC (prPSC) as determined by RT-PCR, western blot, and immunofluorescence. In contrast to HSC, PSC expressed both NGF receptors, although p75NTR expression was weak in prPSC. In contrast to ihPSC TGF-b activated both Smad signaling cascades in prPSC. NGF secretion was diminished by the activin-like kinase (ALK)...

2009-01-01

99

Rubidium uptake by mouse pancreatic islets exposed to 6-hydroxydopamine, ninhydrin, or other generators of hydroxyl radicals  

International Nuclear Information System (INIS)

The purpose was to study the toxicity of drugs known to generate free radicals on isolated pancreatic islets. The accumulattion of "8"6Rb"+ by mouse pancreatic islets was measured in vitro. Exposing the islets to 6-hydroxydopamine, minhydrin, or phenazine methosulphate + NADH inhibited the Rb"+ uptake, whereas paraquat or acetylphenylhydrazine had no effect. This effect of 6-hydroxydopamine was prevented by either of the hydroxyl radical scavengers, sodium benzoate and mannitol, but not by the non-scavenger,urea; ninhydrin was partially protected against by mannitol but not by benzoate. Protection against 6-hydroxydopamine was also afforded by D-glucose but not by L-glucose or 3-O-methyl-D-glucose; none of the sugars protected against ninhydrin. In damaging islet beta-cells and in being protected against by D-glucose, 6-hydroxydopamine closely resembles the diabetogenic drug, alloxan. It is suggested that protection against alloxan may involve ...

100

Percutaneous drainage of abdominal abcess  

Energy Technology Data Exchange (ETDEWEB)

The mortality in undrained abdominal abscesses is high with a mortality rate ranging between 45 and 100%. The outcome in abdominal abscesses, however, has improved due to advances in image guided percutaneous interventional techniques. The main indications for the catheter drainage include treatment or palliation of sepsis associated with an infected fluid collection, and alleviation of the symptoms that may be caused by fluid collections by virtue of their size, like pancreatic pseudocele or lymphocele. The single liver abscesses may be drained with ultrasound guidance only, whereas the multiple abscesses usually require computed tomography (CT) guidance and placement of multiple catheters. The pancreatic abscesses are generally drained routinely and urgently. Non-infected pancreatic pseudocysts may be simply observed unless they are symptomatic or cause problems such as pain or obstruction of the biliary or the ...

2002-09-01

101

Physicochemical basis for formation of renal stones of calcium phosphate origin: calculation of the degree of saturation of urine with respect to brushite  

UK PubMed Central (United Kingdom)

Brushite (CaHPO4·2H2O) was considered to govern the formation of renal calculus of calcium phosphate origin. The degree of saturation of urine with respect to this phase...Full Text Available

1969-10-01

102

Ignition and combustion features of biofuels  

British Library Electronic Table of Contents (United Kingdom)

This paper presents the results of experimental investigations of the ignition and combustion of plant biofuels (wood particles, date stones) and products of their mechanical and thermal treatment (pellets, charcoal) at temperatures typical of the burning process in nonforced furnaces and fixed-bed and fluidized-bed gas producers. The influence of the furnace heat treatment of a fuel on its inflammation and combustion has been revealed. The results have been compared with the known data on the burning of pellets, brown coals, and anthracites and with the calculation by the classical diffusion-kinetic model.

2011-01-01

103

Three-dimensional culture models of mammary gland  

UK PubMed Central (United Kingdom)

The mammary gland is a complex tissue comprised of a branching network of ducts embedded within an adipocyte-rich stroma. The ductal epithelium is a bi-layer of luminal and myoepithelial cells, the...Full Text Available

2009-04-01

104

The effect of lecithin on intestinal cholesterol uptake by rat intestine in vitro  

UK PubMed Central (United Kingdom)

1. Sacs 20 cm long were obtained from the upper half of the small intestine of bile fistula rats (bile duct cannulated 48 hours previously). The sacs were everted, filled with oxygenated phosphate...Full Text Available

1973-03-01

105

The design and performance of a capacitance sensor for two-phase flow concentration measurements in a square duct  

Energy Technology Data Exchange (ETDEWEB)

The use of capacitance sensors for measuring phase concentrations in two-phase flow has gained popularity in recent years. In designing such sensors, there are many issues which must be considered in order to optimize performance: two-phase flow regime, permittivity of the phases, duct geometry, electrical shielding, desired spacial resolution of film thickness, and temperature variation in the flow field. These design issues are discussed and are used to optimize the design of a capacitance sensor which is used to measure vapor volume fraction in annular, two-phase vertical upflow and downflow in a square duct. The sensor was tested and implemented in a 12.7 mm square duct mounted in a flow boiling facility containing FC-72, a low permittivity dielectric fluid ({epsilon}{sub r} = 1.75). Using analytical modeling, an adjustable-length, parallel-plate design was developed and refined to achieve good sensitivity to flow ...

1995-12-31

106

Phenotypic Transition of the Collecting Duct Epithelium in Congenital Urinary Tract Obstruction  

UK PubMed Central (United Kingdom)

Epithelial-mesenchymal transition (EMT) has emerged in recent years as an important process in the development of organ fibrosis in many human diseases. Our previous experience in a nonhuman primate...Full Text Available

2010-01-01

107

Methyl Jasmonate Induces Traumatic Resin Ducts, Terpenoid Resin Biosynthesis, and Terpenoid Accumulation in Developing Xylem of Norway Spruce Stems1  

UK PubMed Central (United Kingdom)

Norway spruce (Picea abies L. Karst) produces an oleoresin characterized by a diverse array of terpenoids, monoterpenoids, sesquiterpenoids, and diterpene resin acids that can protect...Full Text Available

2002-07-01

108

MR imaging of hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Magnetic resonance (MR) images of 18 cases of hilar cholangiocarcinoma were evaluated to compare the effectiveness of Gd-DTPA with that of high dose contrast enhancement computed tomography (HCE-CT) in detecting the primary tumor. The primary tumor was demonstrated as having slightly low intensity compared with liver parenchyma and high intensity compared with the delated bile duct on T1-weighted images. In contrast, MRI using Gd-DTPA, which was carried out in five cases, revealed intense enhancement of the tumor. As the differentiation between cholangiocarcinoma and dilated bile duct was difficult, it was concluded that the use of Gd-DTPA improves the efficacy of MRI in diagnosing cholangiocarcinoma. Gd-DTPA was also effective in differentiating the growth pattern of the tumor: the infiltrating type was demonstrated as thickening of the wall of the bile duct, the polypoid type as a soft tissue mass in the bile ...

109

Liver Flukes: the Malady Neglected  

UK PubMed Central (United Kingdom)

Liver fluke disease is a chronic parasitic inflammatory disease of the bile ducts. Infection occurs through ingestion of fluke-infested, fresh-water raw fish. The most well-known species that cause...Full Text Available

2011-05-01

110

Fundamental investigation of duct/ESP phenomena  

Energy Technology Data Exchange (ETDEWEB)

This report describes in detail the First Generation Duct Injection Model developed for the analysis of the fundamental processes of flue gas desulfurization by sorbent injection. The model is a two- and three-dimensional, multiphase reacting flow analyzer using computational fluid dynamics methods. The gaseous phase is solved in an Eulerian frame while the droplets or particles are tracked in a Lagrangian frame. The model has an associated preprocessor which allow easy problem set up by the use without in-depth knowledge of computational fluid dynamics. The aerodynamics of the First Generation Duct Injection Model have been successfully validated with a number of test cases for which experimental data are available. Data from the Meredosia pilot plant humidification tests have been used to validate the gas and droplet dynamics of the model with good agreement. Comparison of SO{sub 2} removal results using the present model (with one injector) ...

1990-12-01

111

Diagnostic Dilemma in an Unusual Case of Common Bile Duct Obstruction  

UK PubMed Central (United Kingdom)

Biliary obstructions are rarely caused by a foreign body and have received sparse attention. We present an unusual case with pruritis and abdominal pain caused by impacted full length surgical gauze...Full Text Available

2011-06-01

112

Vortex generator induced heat transfer augmentation past a rib in a heated duct air flow  

Energy Technology Data Exchange (ETDEWEB)

The present investigation represents the initial phase of a comprehensive experimental program designed to study the potential for increasing the heat transfer per unit pressure drop in a ribbed duct by positioning vortex generators at key locations in the flow. In particular, the present investigation consists of a rib positioned at the inlet to a rectangular test section with uniform heating at its bottom wall. Local and average Nusselt number results are obtained for a circular rod positioned either immediately above or just downstream of the rib.

1992-02-01

113

Development of radial-flow type internally oil-cooled oil-filled cable  

Energy Technology Data Exchange (ETDEWEB)

A radial-flow type internally oil-cooled oil-filled cable has been developed. This system is characterized in that the oil flows radially through the paper insulation. The thermal resistance of the insulation is equivalently decreased by the radial-flow. The decreased thermal resistance as well as the cooling effect of the oil flow in the central oil duct and the outer oil duct under an aluminum sheath increase the current capacity. A calculation method of cooling characteristics is introduced. The stability of the cable and accessories was confirmed through initial electrical tests and a long-term field test.

1988-01-01

114

Computer control of fuel handling activities at FFTF  

International Nuclear Information System (INIS)

The Fast Flux Test Facility near Richland, Washington, utilizes computer control for reactor refueling and other related core component handling and processing tasks. The computer controlled tasks described in this paper include core component transfers within the reactor vessel, core component transfers into and out of the reactor vessel, remote duct measurements of irradiated core components, remote duct cutting, and finally, transferring irradiated components out of the reactor containment building for off-site shipments or to long term storage. 3 refs., 16 figs.

1985-09-08

115

Computed tomography of hilar cholangiocarcinoma: a new sign  

International Nuclear Information System (INIS)

Thirty-seven patients with histologic proof of cholangiocarcinoma at the confluence were examined by computed tomography (CT) to determine whether this examination is of value in the assessment of these patients for surgery and whether there are any features specific to this type of tumor. Thirty-two patients showed intrahepatic duct dilatation; six of these showed dilatation of ducts in one lobe only. Eighteen patients had intrahepatic low-attenuation areas, while eight had a mass lesion in the porta hepatis. The results of this study show that CT provides useful anatomic information preoperatively but that the appearances are nonspecific. Lobar atrophy is highly suggestive of hilar cholangiocarcinoma, either of long-standing or with unilateral portal venous involvement.

1986-04-14

116

Void fraction measurements using neutron radiography  

Energy Technology Data Exchange (ETDEWEB)

Real-time neutron radiography is being evaluated for studying the dynamic behavior of two-phase flow and for measuring void fraction in vertical and inclined water ducts. This technique provides a unique means of visualizing the behavior of fluid flow inside thick metal enclosures. An air-water flow system was constructed to simulate vapor conditions encountered in a fluid flow duct. Air was injected into the bottom of the duct at flow rates up to 0.47 {ell}/s (1 ft{sup 3}/min). The water flow rate was varied between 0 and 3.78 {ell}/min (0 to 1 gal/min). The experiments were performed at the Pennsylvania State University nuclear reactor facility using a real-time neutron radiography camera. With a thermal neutron flux on the order of 10{sup 6} n/cm{sup 2}{center_dot}s{sup {minus}1} directed through the thin duct dimension, the dynamic behavior of the air bubbles was clearly visible through 5-cm ...

1995-09-01

117

Void fraction measurements using neutron radiography  

Energy Technology Data Exchange (ETDEWEB)

Real-time neutron radiography is being evaluated for studying the dynamic behavior of two phase flow and for measuring void fraction in vertical and inclined water ducts. This technique provides a unique means of visualizing the behavior of fluid flow inside thick metal enclosures. To simulate vapor conditions encountered in a fluid flow duct, an air-water flow system was constructed. Air was injected into the bottom of the duct at flow rates up to 0.47 I/s (1 cfm). The water flow rate was varied between 0--3.78 I/m (0--1 gpm). The experiments were performed at the Pennsylvania State University nuclear reactor facility using a real-time neutron radiography camera. With a thermal neutron flux on the order of 10{sup 6}n/cm{sup 2}/s directed through the thin duct dimension, the dynamic behavior of the air bubbles was clearly visible through 5 cm (2 in.) thick aluminum support plates placed on both sides of ...

1992-12-31

118

Void fraction measurements using neutron radiography  

International Nuclear Information System (INIS)

Real-time neutron radiography is being evaluated for studying the dynamic behavior of two-phase flow and for measuring void fraction in vertical and inclined water ducts. This technique provides a unique means of visualizing the behavior of fluid flow inside thick metal enclosures. An air-water flow system was constructed to simulate vapor conditions encountered in a fluid flow duct. Air was injected into the bottom of the duct at flow rates up to 0.47 ell/s (1 ft"3/min). The water flow rate was varied between 0 and 3.78 ell/min (0 to 1 gal/min). The experiments were performed at the Pennsylvania State University nuclear reactor facility using a real-time neutron radiography camera. With a thermal neutron flux on the order of 10"6 n/cm"2#centre dot#s"-"1 directed through the thin duct dimension, the dynamic behavior of the air bubbles was clearly visible through 5-cm (2-in.)-thick aluminum support ...

1995-01-01

119

The efficacy of interventional therapy for hilar cholangiocarcinoma: a comparison between unilateral and bilateral biliary duct drainage  

International Nuclear Information System (INIS)

Objective: To compare the therapeutic effect of unilateral biliary duct drainage with bilateral biliary duct drainage in the treatment of Bismuth-Corlette II-IV type hilar cholangiocarcinoma in order to provide rational and proper clinical options. Methods: Biliary duct drainage was performed in 80 patients with hilar cholangiocarcinoma. The patients were divided into unilateral drainage group (n = 52) and bilateral drainage group (n = 28). The clinical data and the therapeutic results of the two groups were retrospectively analyzed and compared. Results The two groups were quite comparable in the patient's age, sex, clinical type, drainage way, preoperative total and direct bilirubin level, white blood cell, total protein and albumin, etc. After the treatment, the mean reduction value of the total bilirubin and direct bilirubin was 82.73 #mu#mol/L and 31.71#mu#mol/L respectively in unilateral drainage group, and was 80.28 ...

2009-08-01

120

The unique hypusine modification of eIF5A promotes islet ? cell inflammation and dysfunction in mice  

UK PubMed Central (United Kingdom)

In both type 1 and type 2 diabetes, pancreatic islet dysfunction results in part from cytokine-mediated inflammation. The ubiquitous eukaryotic translation initiation factor 5A (eIF5A), which is the...Full Text Available

2010-06-01

121

The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells  

UK PubMed Central (United Kingdom)

Previous studies using in vitro cell culture systems have shown the role of the dynamin-related GTPase Opa1 in apoptosis prevention and mitochondrial DNA (mtDNA) maintenance. However, it remains to...Full Text Available

2011-07-01

122

Isolation and sequence determination of 5'-terminal oligonucleotide fragments of RNA transcripts synthesized by bacteriophage T3-induced RNA polymerase from T3 DNA.  

UK PubMed Central (United Kingdom)

The nucleotide sequence of the 5'-terminal oligonucleotides produced by pancreatic RNase digestion of bacteriophage T3 RNA polymerase (EC 2.7.7.6) transcripts of T3 DNA has been determined. The sequence...Full Text Available

1980-07-01

123

Endoscopic Ultrasound Guided Fine Needle Aspiration Biopsy in Diagnosis of Pancreatic and Peripancreatic Lesions: A Single Center Experience in Korea  

UK PubMed Central (United Kingdom)

Background/AimsAlthough endoscopic ultrasound guided fine needle aspiration (EUS-FNA) has been introduced and its use has been increasing in Korea, there have not been many reports...Full Text Available

2009-06-01

124

ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic ? cell  

UK PubMed Central (United Kingdom)

Extracellular ATP has been proposed as a paracrine signal in rodent islets, but it is unclear what role ATP plays in human islets. We now show the presence of an ATP signaling pathway that enhances...Full Text Available

2010-04-06

125

Liquid-metal flow in a sharp elbow in a uniform transverse magnetic field  

Science.gov (United States)

In the self-cooling blankets of the Tokamak fusion reactor, a liquid metal, namely liquid lithium, is pumped through a system of ducts to transfer heat and capture neutrons. One of the blanket designs proposed in Argonne National Laboratory's Blanket Comparison and Selection study uses a combination of poloidal and toroidal ducts in order to maximize heat transfer while minimizing net pressure drop. In the design, the poloidal and toroidal ducts meet at sharp, abrupt corners. They were modelled as two identical, straight, semi-infinite, thin-walled, rectangular ducts with 45{degree} miters and joined at a 90{degree} angle in the plane of a strong, uniform magnetic field. While in the toroidal containment vessel (i.e. the blanket), the liquid lithium is subjected to a large electromagnetic body force due to the presence of a strong magnetic field. This body force so dominates the flow as to make ...

1989-01-01

126

Value creation through relationship closeness  

British Library Electronic Table of Contents (United Kingdom)

Globalization and technological innovation are creating dynamic networks or chains of interconnected players, often known as value delivery networks or supply chains, in which a firm, whether manufacturing or service, holds the key to creating and delivering value in the form of offerings to the customers. This idea of value creation and exchange is the foundation stone of relationship marketing and it is considered successful when closeness is said to have been established in the relationship which subsequently leads toward the achievement of objectives. In order to study and understand the creation of value through relationship closeness in a value delivery network particularly at the backward end, a literature review is conducted. A framework is further developed with the help of Interp...

2010-01-01

127

Evidence-Based Drainage of Infected Hydronephrosis Secondary to Ureteric Calculi  

British Library Electronic Table of Contents (United Kingdom)

Abstract Introduction: The obstructed, infected kidney is a urological emergency. It has been accepted that the management of infected hydronephrosis secondary to ureteric stones is through prompt decompression of the collecting system. However, the optimal method of decompression has yet to be established. Materials and Methods: A PubMed and Medline search was performed of all English-language articles from 1960 using key words ?sepsis,?? ?urosepsis,?? ?obstruction,?? ?obstructive pyelonephritis,?? ?pyonephrosis,?? ?infection and hydronephrosis?? ?decompression,?? ?stent,?? ?nephrostomy,?? and ?management.?? The Cochrane database and National Institute for Clinical Effectiveness guidelines were searched using the terms ?sepsis,?? ?urosepsis,?? ?stent,?? ?nephrostomy,?? or ?obstruction.?? ...

2010-01-01

128

Dextranomer/hyaluronic acid copolymer (Deflux) implants mimicking distal ureteral calculi on CT  

Energy Technology Data Exchange (ETDEWEB)

Periureteral or subtrigonal injection of dextranomer/hyaluronic acid (Dx/HA) copolymer (Deflux, Q-Med, Uppsala, Sweden) is an increasingly common endoscopic treatment for vesicoureteral reflux. We report a confusing radiographic finding of bilateral calcified Dx/HA injections initially thought to represent bilateral distal ureteral stones in a boy who presented with intermittent periumbilical pain. Urologists, radiologists, and emergency room physicians should be aware of the potential for calcification of ureteral implants of Dx/HA, and of the potentially confusing radiographic images that may result. (orig.)

2008-01-15

129

Drinking water composition and incidence of urinary calculus: introducing a new index.  

Science.gov (United States)

INTRODUCTION. We searched for a pathophysiologically based feature of major water electrolytes, which may define water quality better than the water hardness, respecting urinary calculus formation. MATERIALS AND METHODS. Utilizing a multistage stratified sampling, 2310 patients were diagnosed in the imaging centers of the provincial capitals in Iran between 2007 and 2008. These were composed of 1755 patients who were settled residents of 24 provincial capitals. Data on the regional drinking water composition, obtained from an accredited registry, and their relationships with the region's incidence of urinary calculi were evaluated by metaregression models. The stone risk index (defined as the ratio of calcium to magnesium-bicarbonate product in drinking water) was used to assess the risk of calculus formation. RESULTS. No correlation was found between the urinary calculus incidence and the amount of calcium, bicarbonate, or the total hardness of the drinking water. ...

2011-01-01

130

Sodium leak detector  

International Nuclear Information System (INIS)

Purpose: To permit accurate detection of sodium leakage by distinguishing between variations in the overflow tank level due to changes in sodium temperature accompanying changes in the power level or operating state of a liquid metal sodium cooled fast breeder, and a reduction in power level due to duct leakage. Constitution: The volume of sodium in the primary cooling system is roughly estimated from the temperatures of hot and cold legs, and the duct leak preset level with respect to the sodium liquid level within an overflow tank when the plant is normal is varied according to the state of the plant. More particularly, the volume of sodium within the overflow tank is calculated on the basis of a signal representing the liquid level detected by a liquid level gauge in the overflow tank and a signal representing the temperature detected by hot leg and cold leg thermometers, thereby obtaining the preset value of the liquid level within the ...

131

Fundamental study on the convective heat transfer augmentation of a wavy type heat exchanger  

Energy Technology Data Exchange (ETDEWEB)

The purpose of the study is to investigate the heat transfer augmentation method for a wavy channel type heat exchanger. Experimental studies were carried out, by installation of flow guide-plates with simple structure, to clarify the effects on the augmentation whether the effects are brought by the flow acceleration or by the increase of intensity of turbulence due to the flow seperation, and to determine optimum shape of flow guide-plates. The shape and dimensions of the experimental apparatus are as follows; channel width H of 30 mm, rectangular section with breadth of 300 mm, wavy duct with a bend angle of 60/sup 0/ and straight pipe of 2H length. Air stream was flowed through the duct with Reynolds number of 1.7 x 10/sup 4/ only. As the results, following conclusions were obtained. (1) Wavy duct with large bend angle and without inserting flow guide-plates could not be expected large effects on the heat transfer ...

1988-06-25

132

Free air flows for the removal of pollutants from car parks; Air-conditioning systems without sheet metal ducts as an alternative to transverse ventilation with sheet-metal ducts. Pt. 1. Freie Luftstroemungen entsorgen Parkraeume; RLT-Anlagen ohne Blechkanaele als Alternative zur Querlueftung mit Blechkanaelen. T. 1  

Energy Technology Data Exchange (ETDEWEB)

In car parks of considerable length, the removal of exhaust emissions, is carried out by air-conditioning systems mainly through transverse ventilation over short routes. The required air-conditioning ducts frequently produce a reduction in the available parking space simply due to their presence, resulting in restrictive effects on the level of acceptance by the users. In such cases, remedial action can be taken by creating ductless longitudinal ventilation. Depending on the required room air quality in the zones with the highest level of pollution, the volumetric flows for longitudinal disposal are no greater than those for conventional transverse ventilation. In conjunction with architecturally clear and positive lighting designs, clearly laid out car parks with a friendly atmosphere can be created which the user will be pleased to accept. (orig./BWI)

1994-03-01

133

Experimental study on two-phase flow regime transition from stratified to slug flow in a large-height horizontal duct  

Energy Technology Data Exchange (ETDEWEB)

The prediction of two-phase flow regime in the horizontal pipings during a loss-of-coolant accident (LOCA) is important for safety analysis of a pressurized water reactor (PWR). The flow regime transition conditions for a horizontal two-phase air-water flow were studied using a large-height, horizontal rectangular duct test section. The duct dimensions were 700 mm in height, 100 mm in width and 28.3 m in length. The experimental criterion for the flow regime transition from the stratified to slug flow regimes, in terms of the local void fraction and the non-dimensional gas-liquid relative velocity, agreed qualitatively with the prediction by the Mishima-Ishii model that is based on an idea that the interfacial waves with the largest growth rate will develop into a slug. However, the transition in the experiment occurred at systematically lower (by about 40 %) relative velocities than the prediction by the Mishima-Ishii model. Therefore, an ...

1992-02-01

134

Evolution of virtual CT laparoscopy for preoperative imaging in laparoscopic cholecystectomy  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to determine the feasibility of virtual endoscopy, named as ''virtual CT laparoscopy'', in the hepatobiliary system prior to laparoscopic cholecystectomy. We applied this technique to 28 patients suspected of having biliary disease. These images were compared and analyzed qualitatively based on visualization of the structures critical to operative cholangiography and surgical findings. Twenty-four patients, who underwent laparoscopic cholecystectomy, were evaluated as follows: the common bile duct and the hepatic duct were adequately visualized in 23 (96%) of the 24 patients, the cystic duct in 21 (88%), the gallbladder opacification in 20 (83%), the liver inferior surface in 20 (83%). Four patients had anatomic variations detected virtual CT laparoscopy and were proven by operative cholangiography and surgical findings. We emphasize that our new technique ...

2002-06-01

135

Diagnostic value of MRI for hepatic hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Objective: To investigate the value of MRI in the diagnosis of hepatic hilar cholangiocarcinoma. Methods: Sixty-four patients with hepatic hilar cholangiocarcinomas confirmed by surgery or pathology underwent MRI using a 1.5-T superconductive MR system including conventional unenhanced MRI, MRCP and dynamic contrast-enhanced MRI with Gd-DTPA. Results: Dilatation of the intrahepatic biliary tree with narrowing, occlusion or filling defects in the hepatic hilar bile ducts was noted in all 64 cases. Unenhanced MR[ showed T_1- and T_2-hyperintense hilar masses in 42 patients and was normal in the remaining 22 patients. The hilar masses demonstrated slow, progressive and delayed enhancement patterns. There was enhancement of the thickened bile duct wall with luminal narrowing in the 22 patients without hilar masses. Conclusion: The characteristic MRI findings of enhancing hepatic hilar mass and bile duct wall thickening together ...

2010-02-01

136

Analysis of the placement of multiple metallic stents in the treatment of hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Objective: To evaluate the clinical efficacy of multiple stents placement in the management of hilar cholangiocarcinoma, especially in the complex cases of which the hepatic ducts are invaded. Methods: Forty-five consecutive patients with hilar cholangiocarcinoma were treated with percutaneous transhepatic placement of two or three self-expandable metallic endoprostheses. The cause of hilar obstructions in these patients were all cholangiocarcinoma, including Bismuth classification type II (n 12), IIIa (n 17), IIIb (n 10), and IV (n 6). Two or 3 stents were placed in the configuration of T, Y or X over the strictures. Results: Stent placement with 2 or 3 endoprostheses was successful in all patients. All patients showed significant decrease in serum bilirubin level. The mortality rate within 30 days of stent placement was 2.2% (1/45). The mean survival and stent patency times were 215.3 d (26- 516 d) and 181.5 d (26-473 d), respectively. Conclusion: Deploying of ...

2007-11-01

137

Vapor fraction measurements in a steam-water duct at atmospheric pressure using neutron radiography  

Energy Technology Data Exchange (ETDEWEB)

Real-time neutron radiography has been used to study the dynamic behavior of two-phase flow and measure vapor fractions in a steam-water duct at atmospheric pressure. This unique experimental technique offers one the opportunity to observe and record on videotape now Patterns and transient behavior of two-phase flow inside opaque containers without perturbing the environment. The neutron radiographic technique is non-intrusive and requires no special transparent window region. Data are recorded simultaneously over a large area of interest. Image processing of the video data can be employed to measure bubble velocities and time-averaged and Instantaneous vapor fractions.

1994-11-11

138

Vacuum system pump down analysis  

Energy Technology Data Exchange (ETDEWEB)

My assignment on the SP-100 Vacuum Vessel Vacuum System Team was to perform a transient pump down analysis for the vacuum vessel that will house the SP-100 reactor during testing. Pump down time was calculated for air and helium. For all cases the proposed vacuum system will be able to pump down the vessel within the required time. The use of a larger rotary piston pump (DUO250) improves the pump down time by 35 minutes and therefore should be considered. The 6-inch duct for the roughing line is optimal, however, because all cases are well below the 24 hour time frame, the 4-inch duct is sufficient. The use of the single turbomolecular pump during pump down is sufficient. A pump down with helium in the vessel and a helium inleakage delays the time to achieve the base pressure marginally and is acceptable.

1990-08-01

139

Treatment of hilar cholangiocarcinoma with inserting biliary double stents  

International Nuclear Information System (INIS)

Objective: To investigate the inserting technique of biliary double stents in treating hilar cholangiocarcinoma. Methods: 6 patients with hilar cholangiocarcinoma (Bismuth IV) were treated by percutaneous transhepatic insertion of biliary stents. Double stents were inserted in each patient. Different inserting methods were adopted according to the branch angles formed by left and right hepatic ducts. Results: The jaundice of all patients alleviated or disappeared obviously after stent implantation. The average difference between post-and pre-operation in the serum total bilirubin level was (104 #+-# 29) #mu#mol/L (P<0.01). Stent obstruction was found in 2 cases after 4 and 6 months respectively. Conclusion: Double stents implantation is effective for the treatment of hilar cholangiocarcinoma. Beware of the angulation between main hepatic duct and adopting different inserting methods. (authors)

2004-10-01

140

Safe design of mud ditches in briquetting factories  

Energy Technology Data Exchange (ETDEWEB)

The authors study technological safety of installing a water spray pressure vessel between electrostatic deduster and coal sludge ducts. These sprays are in use elsewhere for steam generator ash removal. Dust ignition and explosion tests were carried out to examine flame and pressure wave propagation through the vessel into ducts. Water jet diameter, amount of water sprayed and coal dust removed were varied. Pressure waves exceeded 250 Pa. Test results show the vessel to be suitable for installation in briquetting plants due to its flame and explosion barrier effect and extermination of smoldering dust fires. The only disadvantage of the vessel is seen as its water and electric power consumption: about 8 m/sup 3//h of water and 1.5 kW/h of power per vessel serving dedusters of a 2,200 m/sup 2/ rotary brown coal dryer. (MOS).

1987-06-01

141

Modelling gas dynamics in 1D ducts with abrupt area change  

British Library Electronic Table of Contents (United Kingdom)

Most gas dynamic computations in industrial ducts are done in one dimension with cross-section-averaged Euler equations. This poses a fundamental difficulty as soon as geometrical discontinuities are present. The momentum equation contains a non-conservative term involving a surface pressure integral, responsible for momentum loss. Definition of this integral is very difficult from a mathematical standpoint as the flow may contain other discontinuities (shocks, contact discontinuities). From a physical standpoint, geometrical discontinuities induce multidimensional vortices that modify the surface pressure integral. In the present paper, an improved 1D flow model is proposed. An extra energy (or entropy) equation is added to the Euler equations expressing the energy and turbulent pressure ...

2011-01-01

142

Pancreatic endocrine tumours: an out-matching field of cooperation with nuclear medicine; Les tumeurs endocrines du pancreas: un domaine privilegie de la cooperation avec la medecine nucleaire  

Energy Technology Data Exchange (ETDEWEB)

The Zollinger-Ellison syndrome (ZES) is taken as an example of the diagnostic and therapeutic strategy in gastro-entero-pancreatic endocrine tumours, given the standard characteristics of this procedure, whatever the nature of the primitive tumour. Management of ZES includes: anatomical localization of gastrinoma and of possible metastases, in 60 % of cases this step conditioning therapeutic indications and chances of cure; search of a type 1-multiple endocrine neoplasia (MEN A), in 25 % of cases; therapeutic indications: ablative surgery with curative intent in case of gastrinoma and of resectable liver metastases, palliative treatment otherwise: anti-secretory drugs, somatostatin analogues, chemotherapy and interferon {alpha}; long-term follow-up of patients with resected tumour. At each step, somatostatin receptor scintigraphy with indium 111-pentetreotide does play a pivotal role. (author). 110 refs.

1996-12-31

143

Mesenchymal tumors of the pancreas. CT patterns; Tumori mesenchimali del pancreas: aspetti con tomografia computerizzata  

Energy Technology Data Exchange (ETDEWEB)

Purpose of this item is to report the CT patterns of pancreatic mesenchymal lesions and to investigate the capabilities and limitations of this technique in terms of characterization. In selected cases, CT can provide virtually diagnostic information (lipoma and teratoma), or at least highly suggestive findings (NHL, plexiform neurofibroma, lymphangioma). Moreover, knowledge of the variable morphostructural patterns of mesenchymal hisototypes (SCH, Sarcoma etc.) permits to include them in the differential diagnosis of pancreatic masses. [Italian] Scopo di questo rapporto e' descrivere gli aspetti semeiologici dei tumori mesenchimali del pancreas con la TC verificandone le possibilita e i limiti per la caratterizzazione. Pur nella rarita' dei reperti considerati, la TC puo' consentire l'effettiva caratterizzazione in alcuni casi (lipoma, neurofibroma plessiforme, linfangioma) o includere anche istotipi meno ...

1999-10-01

144

Use of integrin-linked kinase to extend function of encapsulated pancreatic tissue  

Energy Technology Data Exchange (ETDEWEB)

We have studied the impact of overexpression of an intracellular signaling protein, integrin-linked kinase (ILK), on the survival and function of encapsulated islet tissue used for the treatment of type 1 diabetes. The dimensions of the encapsulated tissue can impact the stresses placed on the tissue and ILK overexpression shows the ability to extend function of dissociated cells as well as intact islets. These results suggest that lost cell-extracellular matrix interactions in cell encapsulation systems can lead to decreased insulin secretion and ILK signaling is a target to overcome this phenomenon. (communication)

2010-12-15

145

Gamma absorption determination of concentration in a three-component mixture  

International Nuclear Information System (INIS)

A method for the analysis of three-component mixtures is described. The method is used for contact-free determination of component concentration in the mixtures transported via a product duct. Formulae as an aid in choosing the gamma radiation source and estimating the efficiency of measurement are given. The errors of measurement by the method of formaline-water-carbamide mixture is 1-2 %. 9 refs.; 1 fig.

146

Duct and cladding alloy  

Energy Technology Data Exchange (ETDEWEB)

An austenitic alloy having good thermal stability and resistance to sodium corrosion at 700.degree. C. consists essentially of 35-45% nickel 7.5-14% chromium 0.8-3.2% molybdenum 0.3-1.0% silicon 0.2-1.0% manganese 0-0.1% zirconium 2.0-3.5% titanium 1.0-2.0% aluminum 0.02-0.1% carbon 0-0.01% boron and the balance iron.

1983-01-01

147

CT manifestations of ileal dysgenesis  

Energy Technology Data Exchange (ETDEWEB)

Ileal dysgenesis is an uncommon condition of unknown etiology occurring in the distal ileum in the region of the vitelline duct. The CT appearance of this lesion, although not previously described to our knowledge, is characteristic. We report a patient with ileal dysgenesis who had an abdominal CT scan to evaluate chronic iron deficiency anemia and protein-losing enteropathy. Recognition of this lesion by pediatric radiologists is important; so that surgical treatment, which is simple and effective, can be initiated quickly. (orig.)

2007-02-15

148

Scour protection for wind turbine foundations on highly erodible sea bottom  

Energy Technology Data Exchange (ETDEWEB)

Scour around offshore structures is well known. It is caused by the strong eddy formation at the base of the structures protruding from the sea bottom. The strong vortices result in an amplified effective shear stress working on the sea bottom surface adjacent to the structure. When the surrounding sea bottom is lowered the scour protection will end up being a cap on a small hill and when the slopes are getting too steep the scour protection will roll or slide down the sides. It will loose its cohesion and therefore its integrity. This will take place irrespective of the type of scour protection material and the type of scour protection. This report describes scour protections, which can deal with this particular problem. Such a scour protection must be able to sustain the following loads: Be able to follow the lowering of the seabed on its way down; Be resistant to edge scour (scour around the perimeter of the scour protection). The installation of scour protection is not ...

2002-12-01

149

The strong associations between organism characteristics and network architecture  

CERN Document Server

Understanding the dependence and interplay between architecture and function in biological networks has great relevance to disease progression, biological fabrication and biological systems in general. Recent research in complex systems and networks, presents methods to properly mine the architectural interdependence in networks. Guided by such work, we propose methods to associate organism characteristics with network topology by analyzing a large number of architectural patterns. We adopt an automated approach using 11 topological metrics from complex networks to characterize a collection of various kinds of biological networks. Principal component analysis and clustering allow us to extract the indispensable, independent and informative metrics. Using hierarchical linear modeling, we observe that organism characteristics associate with these metrics, surprisingly well. This work can serve as a stepping stone to cataloging biologically relevant topological ...

2009-01-01

150

The evolution of human culture during the later Pleistocene: Using fauna to test models on the emergence and nature of "modern" human behavior  

British Library Electronic Table of Contents (United Kingdom)

It has often been argued that the success and spread of modern humans 50,000years ago was due to a series of key behavioral shifts that conferred particular adaptive advantages. And yet, particularly during the African Middle Stone Age (MSA), some of these "modern" behaviors see only patchy expression across time and space. Recent models have proposed a link between the emergence of modern behaviors and environmental degradation and/or demographic stress. Under these models, modern behaviors represent a form of social/economic intensification in response to stress; if this were the case, signs of subsistence intensification should be more common during periods in which these behaviors are manifested than when they are not. In order to test these models, I analyzed faunal remains from Sibud...

2011-01-01

151

Morphology of modified starches prepared by different methods  

British Library Electronic Table of Contents (United Kingdom)

Morphologies of modified starches prepared using different methods were examined by scanning electron microscopy (SEM). These SEM micrographs provide the following results. To begin with, starch granules underwent a series of changes which resulted in the morphology of modified starch quite different from the native starch with different the methods during the process of modification. For example, hollows emerge on the granules of maltodextrin with low value of dextrose equivalent (DE) prepared by means of spray-drying, but they fell to pieces with the increasing value of DE. The granules of pregelatinized starches manufactured with extrusion technology also showed irregular stone shapes and holes within them while those produced by means of drum-drying presented irregular laminar structur...

2010-01-01

152

Evidence for a 4700-2100 BC palaeoearthquake recorded in a fluvial-archaeological sequence of the Segura River, SE Spain  

British Library Electronic Table of Contents (United Kingdom)

The archaeological excavation of a rock shelter (Abrigo del Pozo) in one of the slopes of the Segura River (SE Spain) has revealed a exceptionally preserved sedimentary record spanning from the Paleolithic to the present-day, which includes an anomalous layer of stones (RFB) fallen from the roof. The sedimentary analysis of the stratigraphic sequence exhumed by the excavation indicates that human occupation of the rock shelter was controlled by fluvial environmental evolution. However, the RFB level resulted in a disturbance of human occupation and normal fluvial sedimentation. From the sedimentary and archaeological pieces of evidence, the RFB level has been interpreted as related to a palaeoearthquake responsible for the collapse of the roof and walls of the rock shelter. The palaeoearth...

2011-01-01

153

Effect of different formulations on tebuconazole residues in stone fruits  

British Library Electronic Table of Contents (United Kingdom)

BACKGROUND: The correlation between pesticide residue levels and formulation of an active substance is often not considered, even if it is reasonable to expect some differences arising from behaviour during dilution and spraying, from adhesion to plant and from degradation. An experimental study to investigate the magnitude of tebuconazole residues as a function of different tebuconazole formulated products was carried out in Italy. The fungicide was applied as wettable powder (WP) and water-dispersible granule (WG) formulations to peach, plum, apricot and nectarine orchards, on four different sites. The fruit samples gained from the field trials were quantitatively analysed by gas chromatography with a nitrogen phosphorus detector (GC/NPD) for tebuconazole residues. RESULTS: Tebuconazole ...

2009-01-01

154

Comparison of the Marginal Fit of Pressable Ceramic to Metal Ceramic Restorations  

British Library Electronic Table of Contents (United Kingdom)

Abstract Purpose: The aim of this in vitro study was to compare the marginal adaptation of a pressed ceramic material, when used with and without a metal substructure, to a traditional feldspathic porcelain-fused-to-metal restoration with a porcelain butt margin. Materials and Methods: A maxillary central incisor typodont tooth was prepared with a 1.5 mm 360degree shoulder with rounded internal line angle, and 30 polyether impressions were made. Dies were poured in type IV dental stone, and 30 restorations were fabricated: 10 metal ceramic restorations (MCR) with porcelain butt joints, 10 pressed to metal restorations (PTM), and 10 all-ceramic restorations (PCR). All restorations were evaluated on their respective dies at 45x magnification using an Olympus SZX-12, measurements of the margi...

2009-01-01

155

Class 1E digital systems studies  

International Nuclear Information System (INIS)

This document is furnished as part of the effort to develop NRC Class 1E Digital Computer Systems Guidelines which is Task 8 of USAF Rome Laboratories Contract F30602-89-D-0100. The report addresses four major topics, namely, computer programming languages, software design and development, software testing and fault tolerance and fault avoidance. The topics are intended as stepping stones leading to a Draft Regulatory Guide document. As part of this task a small scale survey of software fault avoidance and fault tolerance practices was conducted among vendors of nuclear safety related systems and among agencies that develop software for other applications demanding very high reliability. The findings of the present report are in part based on the survey and in part on review of software literature relating to nuclear and other critical installations, as well as on the authors' experience in these areas.

156

Analysis of the changes of vegetation coverage of western Beijing mountainous areas using remote sensing and GIS  

British Library Electronic Table of Contents (United Kingdom)

Mentougou District acts as a crucial component in the ecological buffer in western Beijing mountainous areas, Beijing, China. Using two Landsat MSS/TM images acquired on July 14, 1979 and July 23, 2005, the vegetation coverage of Mentougou District was calculated based on normalized difference vegetation index and spectral mixture analysis (NDVI-SMA) model. Its temporal and spatial changes were analyzed according to digital elevation model (DEM) image, social and economic data. The results showed that the vegetation coverage decreased from 76.4% in 1979 to 72.7% in 2005. Vegetation degradation was probably the result of human disturbance, such as outspreading of resident areas, and coal and stone mining activities, while vegetation restoration might be contributed by the combined effects o...

2009-01-01

157

An historical view of the pineal gland and mental disorders  

British Library Electronic Table of Contents (United Kingdom)

Since Classical Antiquity numerous authors have linked the origin of some mental disorders to physical and functional changes in the pineal gland because of its attributed role in humans as the connection between the material and the spiritual world. The pineal organ was seen as a valve-like structure that regulated the flow of animal spirits through the ventricular system, a hypothesis that took on more vigour during the Middle Ages and the Renaissance. The framework for this theory was ''the three cells of the brain'', in which the pineal gland was even called the ''appendix of thought''. The pineal gland could also be associated with the boom, during this period, of certain legends about the ''stone of folly''. But the most relevant psychopathological role of this organ arrived with Des...

2011-01-01

158

"On the Road" - Reflections on the Security of Vehicular Communication Systems  

CERN Document Server

Vehicular communication (VC) systems have recently drawn the attention of industry, authorities, and academia. A consensus on the need to secure VC systems and protect the privacy of their users led to concerted efforts to design security architectures. Interestingly, the results different project contributed thus far bear extensive similarities in terms of objectives and mechanisms. As a result, this appears to be an auspicious time for setting the corner-stone of trustworthy VC systems. Nonetheless, there is a considerable distance to cover till their deployment. This paper ponders on the road ahead. First, it presents a distillation of the state of the art, covering the perceived threat model, security requirements, and basic secure VC system components. Then, it dissects predominant assumptions and design choices and considers alternatives. Under the prism of what is necessary to render secure VC systems practical, and given possible non-technical influences, ...

2009-01-01

159

Unique approach to an old problem: New technology helps BC Hydro locate heat resistance  

Energy Technology Data Exchange (ETDEWEB)

BC Hydro`s approach to improve the performance of its underground transmission lines by employing new computer technology with fibre optic cables was described. Known as Distributed Temperature Sensing (DTS), the technology is expected to increase the capacity of the most heavily-loaded sections of its seven kilometer underground 230 kV transmission system in the Greater Vancouver area. Although it is also a concern in overhead wires, heating is particularly problematic in underground cable systems. DTS uses opto-electronic equipment to launch a laser light down conventional communications-grade fibre optic cables, installed in the same duct as the cables, or in a spare duct next to them. By using high speed measurements and computer processing, it is possible to determine the temperature all along the fibre with very high accuracy, and to locate any point along the length of the cable line to within two meters over distances up to 10 ...

1997-06-01

160

MR imaging and MR cholangiopancreatography in the preoperative evaluation of hilar cholangiocarcinoma: correlation with surgical and pathologic findings  

International Nuclear Information System (INIS)

The primary aim was to evaluate delayed contrast-enhanced MRI in depicting perineural spread of hilar cholangiocarcinoma (CCC) and consequently to determine the capability of MRI/MRCP for staging CCC. Fifteen patients that underwent MRI/MRCP and surgical treatment were retrospectively included. Two radiologists evaluated MR images to assess delayed periductal enhancement, extent of bile duct stenosis, liver parenchymal and vascular involvement and presence of liver atrophy. An agreement between delayed enhancement of the bile duct walls and perineural neoplastic spread showed a very good correlation factor (0.93). The overall accuracy in detecting biliary neoplastic invasion was higher for delayed T1-weighted images (93.3%) than for the MRCP images (80%), and T1-delayed image increased the MR accuracy in assessing the neoplastic resectability (p < 0.05). MRI correctly predicted vascular involvement in 73% and liver involvement in 80% of the ...

2008-10-01

161

Effect of rib height and pitch of the thermal performance of a passage disturbed by detached solid ribs  

Energy Technology Data Exchange (ETDEWEB)

Laser holographic interferometry and pressure measurements are presented for the effects of rib-to-duct height ratio (H/2B), rib pitch-to-height ratio (Pi/H), and Reynolds number (Re) on the spatially periodic-fully developed turbulent heat transfer and friction in a rectangular duct of width-to-height ratio of 4:1 with an array of ribs detached from one wall at a clearance to rib-height ratio of 0.38. The ranges of H/2B, Pi/H, and Re examined were 0.13 to 0.26, 7 to 13, and 5 {times} 10{sup 3} to 5 {times} 10{sup 4}, respectively. The difference in the H/2B dependence of the thermal performance between the detached and attached solid-rib array is documented H/2B = 0.17 and Pi/H = 10 are found to provide the best thermal performance for the range of parameters tested. Compact heat transfer and friction correlations are developed. Additionally, it is found that heat transfer augmentation with a detached solid-rib array is superior to with a ...

1998-07-01

162

Ectopic expression of Cux1 is associated with reduced p27 expression and increased apoptosis during late stage cyst progression upon inactivation of Pkd1 in collecting ducts  

British Library Electronic Table of Contents (United Kingdom)

Abstract Polycystic kidney diseases (PKD) are inherited disorders characterized by fluid-filled cysts primarily in the kidneys. We previously reported differences between the expression of Cux1, p21, and p27 in the cpk and Pkd1 null mouse models of PKD. Embryonic lethality of Pkd1 null mice limits its study to early stages of kidney development. Therefore, we examined mice with a collecting duct specific deletion in the Pkd1 gene. Cux1 was ectopically expressed in the cyst lining epithelial cells of newborn, P7 and P15 Pkd1CD mice. Cux1 expression correlated with cell proliferation in early stages of cystogenesis, however, as the disease progressed, fewer cyst lining cells showed increased cell proliferation. Rather, Cux1 expression in late stage cystogenesis was associated with increased ...

2011-01-01

163

Diagnosis for the cancer extension of cholangiocarcinoma. The current status  

International Nuclear Information System (INIS)

Described is the diagnosis for the cancer extension of cholangiocarcinoma by various imaging techniques and processes to support the current surgical procedure based on preoperative biliary drainage. The cancer tends to locally extend horizontally and/or vertically and its diagnosis is important for surgical indication. For the indication, multi-detector raw CT (MDCT) and MR cholangio-pancreatography (MRCP) are useful and particularly, the former can give multi-phase (arterial, portal and delayed) images to reconstruct multiplanar (MPR) and CT angiographic 3D images, which have made the previous invasive examinations like angiography and percutaneous transportal contrasting unnecessary. MDCT and MRCP can almost complete the diagnosis of the extension. The operative procedure is decided dependently on the site of the lesion, and of which diagnosis, whether it is hepatic hilar/on upper bile duct or middle/lower ductal, is different. MDCT-MPR and MRCP are virtually ...

2010-07-01

164

Design and analysis of a dust extraction system  

Energy Technology Data Exchange (ETDEWEB)

A dust extraction system removes the contaminated air at source by means of a hood. The extraction system for dust is essentially a ducted air system that prevents excessive employee exposure to dust in the working zone. The four major mechanisms that remove the contaminants in an extraction system are: - capture of contaminants by hoods - transport of contaminated air in duct network - separation of dust in the collector - exhaust of clean air through stack. The current methods of design are based on empirical relations, multi-variable tables, graphs and nomographs that have been derived from the principle of fluid mechanics and particle dynamics. However, the empirical formulae, tables and graphs are used in different geographical locations of the world having different environmental conditions and geo-characteristics of dust particles. Therefore, it is required to establish a rational design method that will be based on analysis of each ...

2006-07-01

165

Solvent effects on biocatalysis in organic systems: equilibrium position and rates of lipase catalyzed esterification.  

Science.gov (United States)

Porcine pancreatic lipase immobilized on celite particles has been employed as a catalyst for the esterification of dodecanol and decanoic acid in a predominantly organic system. Solvent influence on the equilibrium position and on the catalyst activity has been studied using 20 solvents, including aliphatic and aromatic hydrocarbons, ethers, ketones, nitro- and halogenated hydrocarbons, and esters. The equilibrium constant for esterification correlates well with the solubility of water in the organic solvent, which in turn shows a good relationship with a function of Guttman's donor number and the electron pair acceptance index number of the solvent. This may be rationalized in terms of the requirements for solvation of water and of the reactants. The catalyst activity, measured as the initial rate of the esterification reaction, is best correlated as a function of both n-octanol-water partition coefficient (log P) and either the electron pair acceptance index or ...

1991-12-01

166

Isolation of full-length putative rat lysophospholipase cDNA using improved methods for mRNA isolation and cDNA cloning  

Energy Technology Data Exchange (ETDEWEB)

The authors have cloned a full-length putative rat pancreatic lysophospholipase cDNA by an improved mRNA isolation method and cDNA cloning strategy using (/sup 32/P)-labelled nucleotides. These new methods allow the construction of a cDNA library from the adult rat pancreas in which the majority of recombinant clones contained complete sequences for the corresponding mRNAs. A previously recognized but unidentified long and relatively rare cDNA clone containing the entire sequence from the cap site at the 5' end to the poly(A) tail at the 3' end of the mRNA was isolated by single-step screening of the library. The size, amino acid composition, and the activity of the protein expressed in heterologous cells strongly suggest this mRNA codes for lysophospholipase.

1987-03-24

167

Growth factor signalling in the regulation of -cell fate  

British Library Electronic Table of Contents (United Kingdom)

Glucagon plays critical roles in regulating glucose homeostasis, mainly by counteracting the effects of insulin. Consequently, the dysregulated glucagon secretion that is evident in type 2 diabetes has significant implications in the pathophysiology of the disease. Glucagon secretion from pancreatic -cells has been suggested to be modulated by blood glucose, signals from the nervous system and endocrine components. In addition to these regulators, intraislet factors acting in a paracrine manner from neighbouring -cells are emerging as central modulator(s) of -cell biology. One of the most important of these paracrine factors, insulin, modulates glucagon secretion. Indeed, the -cell-specific insulin receptor knockout (IRKO) mouse manifests hypersecretion of glucagon in the postprandial stag...

2011-01-01

168

Tank of sodium cooled fast reactor  

International Nuclear Information System (INIS)

Object: To provide a tank, which can safely and reliably accommodate high temperature sodium containing radioactive substance in case of occurrence of an accident in a sodium system and thus prevent spread of contamination. Structure: A sodium drain duct inserted into a tank from above the tank is provided at the position of its lower end with a buffer means for preventing direct flow-down of sodium to a bottom plate. A means for preventing the discharge of radioactive substance to the cover gas is provided above the lower end of the sodium drain tube so as to surround the sodium drain tube. (Kamimura, M.).

169

Problems in modeling of small break LOCA. Technial report  

Energy Technology Data Exchange (ETDEWEB)

The report deals with: (1) two-phase flow regime transitions, (2) liquid entrainment in break flow, (3) vapor pull-through, and (4) CCFL in horizontal ducts. The first three processes influence the mass flow through the break, whereas the fourth one imposes a limit on liquid flow from the steam generator through the hot leg break into the core. Correlations available in the literature which deal with these processes are presented and applied to a hot leg of a PWR, LOFT and Semiscale for quantitative estimates, as well as for determining the scale distortion in the latter two facilities.

1980-10-01

170

Mixed convection flow in a horizontal rectangular channel subjected to a horizontal thermal gradient  

British Library Electronic Table of Contents (United Kingdom)

This paper deals with a mixed convection water flow in a horizontal rectangular duct, uniformly heated from one lateral vertical wall and thermally insulated elsewhere. The supplied heat flux induces a secondary flow, which structure is constituted of one longitudinal roll in the considered aspect ratio (??=?1.9), embedded into a return flow of possibly large stream wise extension (up to twenty channel heights). Such situation induces helicoidal trajectories for the fluid flow particles, which contributes to a heat transfer enhancement compared to purely forced convection flow.

2011-01-01

171

Mixed convection flow in a horizontal rectangular channel subjected to a horizontal thermal gradient  

Science.gov (United States)

This paper deals with a mixed convection water flow in a horizontal rectangular duct, uniformly heated from one lateral vertical wall and thermally insulated elsewhere. The supplied heat flux induces a secondary flow, which structure is constituted of one longitudinal roll in the considered aspect ratio (? = 1.9), embedded into a return flow of possibly large stream wise extension (up to twenty channel heights). Such situation induces helicoidal trajectories for the fluid flow particles, which contributes to a heat transfer enhancement compared to purely forced convection flow.

2011-04-01

172

Los Alamos DP West Plutonium Facility decontamination project  

Energy Technology Data Exchange (ETDEWEB)

The DP West Plutonium Facility operated by the Los Alamos National Laboratory, Los Alamos, New Mexico, was decontaminated between April 1978 and April 1981. The facility was constructed in 1944 to 1945 to produce plutonium metal and fabricate parts for nuclear weapons. It was continually used as a plutonium processing and research facility until mid-1978. Decontamination operations included dismantling and removing gloveboxes and conveyor tunnels; removing process systems, utilities, and exhaust ducts; and decontaminating all remaining surfaces. This report describes glovebox and conveyor tunnel separations, decontamination techniques, health and safety considerations, waste management procedures, and costs of the operation.

1982-01-01

173

Improvement of the efficiency of a bare solar collector by means of turbulence promoters  

Energy Technology Data Exchange (ETDEWEB)

A steady-state mathematical model was developed for a bare collector. Results obtained by previous authors for heat transfer and friction in rectangular ducts with periodic disturbances were employed to evaluate the effect of such disturbances on bare collector efficiency and on its pressure drop. An effective efficiency, which takes into account extra heat obtained and additional mechanical (electric) energy consumption for moving air when heat-transfer augmentation devices are employed, was defined. Simulation results are given for a bare collector, with and without perturbations, showing efficiency and effective efficiency dependence on collector dimensions, solar radiation intensity, disturbance diameter and pitch for collector performance optimization. (author).

1990-01-01

174

Inherent safe heat removal in advanced medium-sized high-temperature reactors  

International Nuclear Information System (INIS)

One of the main points for the inherent safety of a pebble bed high temperature reactor (HTR) is to guarantee the safe removal of the after-heat in case of a break-down of all active cooling systems like heat-exchangers or liner-cooling. This will be necessary because it is well known today that graphite pebble bed fuel elements stay intact, if the accident temperature is below 1600 deg. C. Therefore the heat must be taken out of the reactor system by passive, natural law heat-transfer mechanism so that the maximum fuel temperature stays below the specified limit. Today medium-sized HTRs with a power of 750 MW_t_h and more (TGTR-300, HTR 500) reach temperatures of more than 2400 deg. C in small parts of the core in such hypothetical accidents. A possible way to realize the inherent safe heat removal in advanced medium-sized HTRs is to change the form of the core. Instead of employing the standard cylindrical geometry a plate shaped core should be preferred, described by the proportion ...

1990-04-01

175

Hyperthermia in the Treatment of Cholangiocarcinoma: Development and Testing of an Endobiliary Microwave Device  

International Nuclear Information System (INIS)

Purpose: The aim of this study was to create, perfect and test a hyperthermia balloon catheter for local treatment of cholangiocarcinoma. The device should induce hyperthermia in tumor tissue by acting locally in the bile duct lumen in contact with the tumor-infiltrated duct wall. In addition, it should exert tissue compression to cause an appreciable reduction in tumor microvasculature flow, thus improving thermal performance. Methods: According to the design specifications, the working temperature range should allow the device to be used for hyperthermia therapy either in combination with radiation and/or chemotherapy(radio/chemo-sensitizing effect at 42-45 deg. C) or alone (induction of coagulation necrosis above 65 deg. C). The balloon serves as an anchoring system during treatment and as a functional element to induce tissue compression. In vitro mechanical evaluation of the pressure/volume relationship, with the balloon inside rigid ...

2003-08-01

176

Phase I Study of Conformal Radiotherapy and Concurrent Full-Dose Gemcitabine with Erlotinib for Unresected Pancreatic Cancer.  

Science.gov (United States)

PURPOSE: To determine the recommended dose of radiotherapy when combined with full-dose gemcitabine and erlotinib for unresected pancreas cancer. METHODS AND MATERIALS: Patients with unresected pancreatic cancer (Zubrod performance status 0-2) were eligible for the present study. Gemcitabine was given weekly for 7 weeks (1,000 mg/m(2)) with erlotinib daily for 8 weeks (100 mg). A final toxicity assessment was performed in Week 9. Radiotherapy (starting at 30 Gy in 2-Gy fractions, 5 d/wk) was given to the gross tumor plus a 1-cm margin starting with the first dose of gemcitabine. A standard 3 plus 3 dose escalation (an additional 4 Gy within 2 days for each dose level) was used, except for the starting dose level, which was scheduled to contain 6 patients. In general, Grade 3 or greater gastrointestinal toxicity was considered a dose-limiting toxicity, except for Grade 3 anorexia or Grade 3 fatigue alone. RESULTS: A total of 20 patients were treated (10 men and 10 ...

2011-05-01

177

Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin.  

Science.gov (United States)

Pancreatic amyloid deposits of amylin are a hallmark of Type II diabetes and considerable evidence indicates that amylin oligomers are cytotoxic to beta-cells. Many efforts are presently spent to find out naturally occurring molecules, or to design synthetic ones, able to hinder amylin aggregation or to protect cells against aggregate cytotoxicity. In this context, a protective effect of some polyphenols against amyloid cytotoxicity was reported. Actually dietary polyphenols are endowed with multiple health benefits, and extra virgin olive oil is attracting increasing interest as a source of these substances. Here, we investigated the effects on amylin aggregation and cytotoxicity of the secoiridoid oleuropein aglycon, the main phenolic component of extra virgin olive oil. We found that oleuropein, when present during the aggregation of amylin, consistently prevented its cytotoxicity to RIN-5F pancreatic beta-cells, as determined by the ...

2009-07-18

178

New approach for in vivo detection of insulitis in type I diabetes: activated lymphocyte targeting with "1"2"3I-labelled interleukin 2  

International Nuclear Information System (INIS)

Insulitis is considered the histopathological hallmark of type I diabetes. In the non-obese diabetic (NOD) mouse, diabetes has never been observed in the absence of insulitis. The in vivo detection of insulitis could be of relevance for early prediction of diabetes. As approximately 15% of islet-infiltrating lymphocytes express interleukin 2 receptors, the authors have labelled recombinant inter-leukin 2 with "1"2"3I and used this radiopharmaceutical to detect insulitis by gamma camera imaging. The authors studied 71 prediabetic NOD and 27 normal Balb/c mice. Labelled #alpha#-lactalbumin was used as the control protein. In the first set of experiments the tissue distribution of radiolabelled interleukin 2 in isolated organs from animals sacrificed at different time points was studied. Higher radioactivity was detected in the pancreas of NOD mice injected with labelled interleukin 2, as compared to NOD mice receiving labelled #alpha#-lactalbumin. In another set of experiments, gamma ...

1994-01-01

179

Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent  

Science.gov (United States)

BackgroundDespite an ever-improving understanding of the molecular biology of cancer, the treatment of most cancers has not changed dramatically in the past three decades and drugs that do not discriminate between tumor cells and normal tissues remain the mainstays of anticancer therapy. Since Hsp90 is typically involved in cell proliferation and survival, this is thought to play a key role in cancer, and Hsp90 has attracted considerable interest in recent years as a potential therapeutic target.MethodsWe focused on the interaction of Hsp90 with its cofactor protein p60/Hop, and engineered a cell-permeable peptidomimetic, termed "hybrid Antp-TPR peptide", modeled on the binding interface between the molecular chaperone Hsp90 and the TPR2A domain of Hop.ResultsIt was demonstrated that this designed hybrid Antp-TPR peptide inhibited the interaction of Hsp90 with the TPR2A domain, inducing cell death of breast, pancreatic, renal, lung, prostate, and gastric cancer ...

2011-01-14

180

The CO{sub 2} gasification kinetics of olive residue  

Energy Technology Data Exchange (ETDEWEB)

Orujillo, sometimes called wood matter from pressed oil-stone (WPOS) is a residue from the olive oil mill industry. The generation of this biomass residue is concentrated in small areas allowing its use as fuel for medium size gasification and combustion plants. Rates of gasification of WPOS char were measured in a TGA at various temperatures (800-850-875-900-950{sup o}C), CO{sub 2} partial pressures (0.20-0.35-0.50 bar) and CO partial pressures (0.0-0.20 bar). The experiments were carried out with a monolayer bed of very fine particles well exposed to the gas so as to minimise mass and heat transfer resistances. Two kinetic models, the nth order model and Langmuir-Hinshelwood model, have been used to fit with the reactivity data. For pure CO{sub 2} experiments the kinetic parameters of nth order model were E=133 kJ/mol and n=0.43. The Langmuir-Hinshelwood kinetic model clearly describes the observed CO inhibition effect on the CO{sub 2} gasification.(author)

2003-02-01

181

Some medical applications of thermomechanically treated titanium nickelide  

Energy Technology Data Exchange (ETDEWEB)

An original device and a method of its application for restoring of the function of relatively incompetent valves (both patented) are elaborated. Application of the new device allows to lower the difficulty of surgical treatment, to decrease the duration of operation and post-operative period. The long-term results of six-year long experience of its application are presented. The patients examination after 2,5-3,0-year post-operation period shows perfect vein valve correction. A device for stone extraction from tubular organs (patented) fabricated with titanium nickelide superelastic alloy is presented. The new suggested design is free of the drawback inherent in the previous one. The working element of the device is formed as a truncated cone or a truncated cone coaxial with the cylinder (the previous design was formed as a full cone) that prevents overstraining and residual strain accumulation during the manipulation process. Since the first publication the ...

2001-11-01

182

Silicate bonded ceramics of laterites  

International Nuclear Information System (INIS)

Sodium silicate is vacuum impregnated in bauxite waste (red mud) at room temperature to develop ceramics of mechanical properties comparable to the sintered ceramics. For a concentration up to 10% the fracture toughness increases from 0.12 MNm"-"3"/"2 to 0.9 MNm"-"3"/"2, and the compressive strength from 7 MNm"-"2 to 30 MNm"-"2. The mechanical properties do not deteriorate, when soaked in water for an entire week. The viscosity and the concentration of the silicate solution are crucial, both for the success of the fabrication and the economics of the process. Similar successful results have been obtained for bauxite and lime stone, even though the latter has poor weathering properties. With scanning electron microscopy and energy dispersive analysis, an attempt is made to identify the crystals formed in the composite, which are responsible for the strength. The process is an economic alternative to the sintered ceramics in the construction industry in the tropical ...

2006-06-16

183

Proposing radioactivity limits for building materials  

International Nuclear Information System (INIS)

A nation-wide survey of natural radioactivity in building materials was conducted during 1982-1984. Samples including industrial wastes, by-products and common building materials were collected from main building material manufactories in 29 provinces except Taiwan. The results of exposure rates, specific activities and release rate for "2"2"2Rn are presented. The specific activities of common materials are listed in declining order as follows: clay bricks > common concrete and sandstones > limes and ordinary cement. The highest level was found in breeze bricks made of stone coal, phosphogypsum and red mud with high intrinsic radioactivity. Therefore, these raw materials should be strictly controlled in manufacturing building materials. The measurement results also showed that the typical specific activities of common building materials in our country were "2"2"6Ra 50 Bq/kg, "2"3"2Th 50 Bq/kg and "4"0K 500 Bq/kg. Based on the surveyed results and foreign ...

184

Problems of waste disposal in the handling of natural radioactive material not subject to authorisation  

International Nuclear Information System (INIS)

With the exception of some minerals, the specific activity of natural radioactive material is below 370 Bq/g, their handling thus not being subject to authorization or the duty of reporting according to section 4 para. 2 of the Radiological Protection Ordinance. Moreover, there is required no handling license for prospecting, mining and processing of radioactive minerals; they are subject to the procedures for the plans of operation of the mining laws of the Federal States. License-free handling of natural radioactive material may result in the production of radioactive waste, the disposal of which must be authorized according to sect. 47 of the Radiological Protection Ordinance if the specific activity exceeds the free amounts of column 4 in Table IV of Appendix IV by a factor of 10"-"4/g. This inconsistency is discussed by means of the following examples: (1) fly ash and slag from coal power plants, (2) flue dust from sintering plants, (3) red mud from aluminium production, (4) ...

1980-05-01

185

Metallic and non-metallic properties of one-dimensional peanut-shaped fullerene polymers  

British Library Electronic Table of Contents (United Kingdom)

Some kind of one-dimensional (1D) peanut-shaped fullerene polymers (PSFPs) exhibit metallic properties, but their occurrence conditions are not yet clarified. By using the VASP (Vienna ab-initio simulation package) with density functional theory (DFT) and projector augmented wave (PAW) method, we have performed first-principles electronic structure calculations of four basic 1D PSFPs, T1, T2, T6, and T7 (the name of T1-T6 is the same as that of Wang et al. [9]) and two associated 1D PSFPs, T1SW1 and T6SW that are created by generalized Stone-Wales transformation (GSW) from T1 and T6. We found that almost regular six-membered rings connected throughout the tube are necessary to get metallic properties for the 1D PSFPs, although there may be several other conditions to expect metallic proper...

2011-01-01

186

Investigation of a mineral melting cupola furnace. Part II. Mathematical modeling  

Energy Technology Data Exchange (ETDEWEB)

A mathematical model of a mineral melting cupola furnace for stone wool production has been developed for improving cupola operation. The 1-D, first-engineering-principles model includes mass and heat balances for the gas phase, five solid phases, and four liquid phases. The gas and solid/liquid phases flow countercurrently. Seven chemical reactions account for the conversions of coke, iron oxide, limestone, and gaseous species. The heterogeneous reactions of coke conversion are limited by both kinetics and mass transport. Heat transfer between phases is modeled including both convection and radiation. The model predicts gas concentrations; mass flow rates; and temperature profiles of the solid, melt, and gas in the cupola, as well as heat loss to the water-cooled walls. Inputs to the model include the coke, rock, and blast air properties, the blast air amount, and the coke percentage in the charge. The unknown model parameters are estimated on the basis of ...

2003-12-24

187

Three-Dimensional Mixed Convection Heat and Mass Transfer in a Rectangular Duct: Case of Longitudinal Rolls  

British Library Electronic Table of Contents (United Kingdom)

This article presents numerical study of 3-D thermosolutale mixed convection (TSMC) in horizontal rectangular channels. The contribution of this work is to characterize the travelling wave's appearance and to generalize the behavior of Poiseuille-Rayleigh-Benard (PRB) systems for a broad range of dimensionless parameters, which control the double diffusive mixed convection. The numerical results consist of analyzing the flow regimes of the steady longitudinal thermoconvectives rolls for the case of purely thermal mixed convection (TMC) and for both thermal and mass transfer (TSMC). The transition from opposed volume forces to cooperating ones at fixed Rayleigh (Ra), Reynolds (Re), and Lewis (Le) numbers, considerably affects the birth and the development of the longitudinal rolls (noted R/...

2011-01-01

188

The expression pattern of scygonadin during the ontogenesis of Scylla paramamosain predicting its potential role in reproductive immunity  

British Library Electronic Table of Contents (United Kingdom)

The antimicrobial peptide scygonadin (Scy) was first isolated from the gonad of Scylla serrata and its gene is predominantly expressed in the ejaculatory duct of adult males. Thus, its function was predicted to be associated with reproductive immunity, but this is still unclear and needs further investigation. In our study, the expression pattern of Scy at different developmental stages of both male and female S. paramamosain was investigated, so that the potential function of this peptide could be examined. Using real-time quantitative PCR, Scy mRNA transcripts were demonstrated obviously in the vulnerable embryos and larvae-zoea I but very weakly detected in the larvae-zoea III, megalops and juveniles. The gene expression pattern showed a decreasing trend during the early developmental s...

2011-01-01

189

Radiation therapy in the treatment of hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

The incidence of hilar cholangiocarcinoma is very rare worldwide. Radical resection is the only prognostic factor for long survival in patients with hilar cholangiocarcinoma. Postoperative radiation therapy can improve local control and survival rates for patients with palliative resection, but it remains controversial in patients with radical resection. Biliary drainage can effectively release bile duct obstruction for the majority of patients with locally advanced disease, and may even prolong survival when combined with radiation therapy. Radiation therapy includes extrernal beam therapy alone, external beam therapy with intraluminal brachytheapy and new radiation technique, such as three dimentional conformal therapy and intensity modulated radiation therapy. The propective randomized clinical study is needed for further investigation in the role of combined modality therapy especially for hilar cholangiocarcinoma. (authors)

2007-10-01

190

Numerical and experimental investigation of shellside characteristics for RODbaffle heat exchanger  

Energy Technology Data Exchange (ETDEWEB)

RODbaffle heat exchanger is a kind of shell-and-tube heat exchanger with eminent performance. Because of the characteristics of tube bundle support structure, fluid flow on shellside is longitudinal and periodical, and fluid flow is of symmetry in landscape orientation. According to the fluid flow characteristics on shellside and ignoring the impact of inlet, outlet and shell wall, a periodic flow unit duct was taken as the simplified model of the shellside to perform numerical simulation by using CFD code, FLUENT. It was found that the both errors in magnitude of the main fluid velocities and heat transfer coefficients between results of simulation and that of experiment or correlations are less than 10%, and the errors of pressure drop between simulation and correlation are no more than 20%. The detailed characteristics and relation of fluid flow and heat transfer on shellside of the RODbaffle heat exchanger were analyzed using the simulation results. (author)

2008-05-15

191

Multidetector Computed Tomography in the Preoperative Workup of Hilar Cholangiocarcinoma  

International Nuclear Information System (INIS)

Hilar cholangiocarcinoma is associated with a dismal prognosis; however, curative resection may offer a chance of cure. Various factors should be considered in the surgical planning for curative resection. These factors include extent of bile duct involvement, relationship between portal vein and tumor involvement, diffuse hepato duodenal ligament infiltration, vascular invasion, lymph node metastasis, peritoneal seeding, and hepatic volume. Using high-quality volume data from multidetector-row computed tomography (MDCT) and adequate postprocessing images, radiologists can provide various types of information, imperative for curative resection of a hilar cholangiocarcinoma. This review illustrates the role of MDCT in the preoperative workup of hilar cholangiocarcinoma.

2009-10-01

192

Microgravity two-phase flow regime modeling  

Energy Technology Data Exchange (ETDEWEB)

A flow pattern or flow regime is the characteristics spatial distribution of the phases of fluid in a duct. Since heat transfer and pressure drop are dependent on the characteristic distribution of the phases, it is necessary to describe flow patterns in an appropriate manner so that a hydrodynamic or heat transfer theory applicable to that pattern can be chosen. The objective of the present analysis is to create a flow regime map based on physical modeling of vapor/liquid interaction phenomena in a microgravity environment. In the present work, four basic flow patterns are defined: dispersed flow, stratified flow, slug flow, and annular flow. Fluid properties, liquid and vapor flow rates, and pipe size were chosen as the principal parameters. It is assumed that a transition from one flow pattern to another will occur when there is a change in the dominant force which controls that flow pattern. The forces considered in this modeling are surface tension force, both ...

1987-01-01

193

Fundamental study of heat transfer and flow situation around a spacer (in the case of a cylindrical rod as a spacer)  

International Nuclear Information System (INIS)

This paper describes the heat transfer augmentation and the flow situation around a single spacer (a cylindrical rod) on the heated surface of a parallel plate duct in order to examine basically the effects of the spacer in the fuel elements of a high temperature gas-cooled reactor. The ends of the cylindrical rod contact the upper and lower planes. A thermosensitive liquid crystal film is used to indicate the effective area for the heat transfer. The mean Nusselt number, which is estimated within the optional distance from the spacer to the downstream direction, peaks at a dimensionless distance of X/D = 1-3, and after that decreases gradually with the flow direction. The manner in which heat transfer corresponds to the flow situation is also examined. The horseshoe vortex, produced around the spacer, affects the wake and contributes to the increase of the local heat transfer. (author).

1988-01-01

194

Fabrication of core demonstration experiments for irradiation in the FFTF [Fast Flux Test Facility  

International Nuclear Information System (INIS)

A major new initiative to develop and irradiate a long-lived, mixed-oxide (MOX) fuel system in the Fast Flux Test Facility (FFTF) has been implemented by Westinghouse Hanford Company for the U.S. Department of Energy. The purpose of this new fuel system, called the core demonstration experiment (CDE), is to demonstrate the capability of achieving a 3-yr life in a prototypical, heterogeneous reactor environment under prototypical power and temperature conditions. Ten fuel and six blanket CDEs are establishing the performance characteristics of entire fuel assemblies of wire-wrapped, large-diameter, annular-pellet, advanced MOX fuel pins with the tempered martensitic HT-9 alloy cladding and end caps, HT-9 wire wrap, and an HT-9 duct in a heterogeneous array with the blanket assemblies. The CDE performance characteristics are confirming the basis for design, fabrication, and irradiation of the CDE.

1990-06-10

195

Core demonstration lead experiments for irradiation in FFTF  

International Nuclear Information System (INIS)

A major new initiative to develop and irradiate a long-life mixed oxide fuel system in the Fast Flux Test Facility (FFTF) has been implemented by the Westinghouse Hanford Company at the Hanford Engineering Development Lab. for the US Dept. of Energy. The purpose of this new fuel system, called the Core Demonstration Experiment (CDE), is to demonstrate the capability of achieving a 3-yr life in a prototypical heterogeneous reactor environment under prototypical power and temperature conditions. Three Core Demonstration Lead Experiments (CDLEs) will establish the performance characteristics of entire fuel assemblies of wire-wrapped, large diameter, advanced oxide fuel pins with HT-9 stainless steel alloy cladding and wire wrap and an HT-9 duct. Their performance characteristics provided the basis for design, fabrication, and irradiation of the CDE.

1987-06-07

196

Conceptual HALT (Hydrate Addition at Low Temperature) scaleup design: Capital and operating costs: Part 5. [Hydrate addition at low temperature for the removal of SO/sub 2/  

Energy Technology Data Exchange (ETDEWEB)

Hydrate addition at low temperature (or the HALT process) is a retrofit option for moderate SO/sub 2/ removal efficiency in coal burning utility plants. This dry FGD process involves injecting calcium based dry hydrate particles into flue gas ducting downstream of the air preheater where the flue gas temperature is typically in the range of 280-325/degree/F. This report is comprised of the conceptual scaleup design of the HALT process to a 180 MW and a 500 MW coal fired utility station followed by detailed capital and operating cost estimates. A cost sensitivity analysis of major process variables for the 500 MW unit is also included. 1 fig.

1988-12-01

197

An investigation of the thermal performance of an oil filled transformer winding  

Energy Technology Data Exchange (ETDEWEB)

Manufacturers may be required to design transformers to overload specifications. Oil viscosity changes and loss variation with temperature are not accounted for in the industry loading guide. A comprehensive test program was performed using a winding assembly with imbedded thermocouples. Steady state and transient tests were performed for natural and non-directed forced oil circulation. The temperature distribution in the winding was not linear with height as usually assumed. A large number of temperature sensors is required to determine the hot spot location. The location of the hot spot was found to be different and less predictable for natural oil circulation compared with non-directed forced oil circulation especially during overload conditions. This paper reports that improved loading guide equations were developed to account for oil viscosity, resistance change, cooling duct oil rise, and location of the hot spot.

1992-07-01

198

A fundamental study of the heat transfer and flow situation around a spacer  

International Nuclear Information System (INIS)

This paper describes the heat transfer augmentation and flow situation around a single spacer (a circular cylinder) on a heated surface in a parallel plate duct in order to examine basically the effects of the spacer in the fuel elements of a High Temperature Gas-cooled Reactor. A thermosensitive liquid crystal film was used to clarify the effective region of the heat transfer. The mean Nusselt number, which was estimated within arbitrary distance from the spacer to the downstream direction, took a peak at the dimensionless distance X/D = 1 #approx# 3, and after that decreased gradually with flow direction. How heat transfer corresponds to the flow situation is also examined. The horseshoe vortex, produced around the spacer, affects the wake and contributes to the increase of the local heat transfer. (author).

1986-01-01

199

Treatment of cancer of the pancreas by intraoperative electron beam therapy: physical and biological aspects  

Energy Technology Data Exchange (ETDEWEB)

Radiation therapy has had a significant and an expanded role in the management of cancer of the pancreas during the last decade. In particular, for locally advanced disease, radiation therapy has improved the median survival of patients to 1 year. Intraoperative electron beam therapy has been applied to unresectable and resectable pancreatic cancer in an attempt to enhance local control of disease and to improve patient survival. This paper presents a survey of the role of radiation therapy in treatment of cancer of the pancreas, provides information on the radiobiological aspects of this treatment modality and details the physical and dosimetric characteristics of intraoperative radiation therapy with electrons. Presented are the design specifics of an applicator system, central axis beam data, applicator parameters, dose distribution data, shielding, treatment planning and means of verification. Emphasis is placed on the collaboration and cooperation necessary ...

1989-01-01

200

Treatment of cancer of the pancreas by intraoperative electron beam therapy: physical and biological aspects  

International Nuclear Information System (INIS)

Radiation therapy has had a significant and an expanded role in the management of cancer of the pancreas during the last decade. In particular, for locally advanced disease, radiation therapy has improved the median survival of patients to 1 year. Intraoperative electron beam therapy has been applied to unresectable and resectable pancreatic cancer in an attempt to enhance local control of disease and to improve patient survival. This paper presents a survey of the role of radiation therapy in treatment of cancer of the pancreas, provides information on the radiobiological aspects of this treatment modality and details the physical and dosimetric characteristics of intraoperative radiation therapy with electrons. Presented are the design specifics of an applicator system, central axis beam data, applicator parameters, dose distribution data, shielding, treatment planning and means of verification. Emphasis is placed on the collaboration and cooperation necessary ...

201

Studies on the biological effects of chemical defense mechanisms in vivo activated by low-dose irradiation  

International Nuclear Information System (INIS)

Active oxygens produced by low-dose irradiation can induce the synthesis of proteins involved in the active oxygen reduction path and can activate the chemical self-defense mechanisms in vivo, which can alleviate the injuries caused by active oxygens themselves. The following findings suggests that it is not only by low-dose irradiation that can induce the responses described above but also by any physical and/or chemical stresses which can produce small amount of active oxygens in vivo. 1. X-irradiation with 0.5 Gy and/or water immersion and restraint induced heat shock protein (HSP)70 in rat stomach cells. HSP70 was also induced in adrenal cells by paraquat administration. 2. The SOD activity in pancreas of rat significantly increased by #gamma#-irradiation with 0.5 Gy. 0.5 Gy irradiation preceeding the alloxan administration significantly suppressed the increase in pancreatic lipid peroxides and in blood glucose levels, degranulation in #beta# cells, and ...

202

Lipase catalyzed esterification of glycidol in organic solvents  

Science.gov (United States)

The authors studied the resolution of racemic glycidol through esterification with butyric acid catalyzed by porcine pancreatic lipase in organic media. A screening of seven solvents (log P values between 0.49 and 3.0, P being the n-octanol-water partition coefficient of the solvent) showed that neither log P nor the logarithm of the molar solubility of water in the solvent provides good correlations between enantioselectivity and the properties of the organic media. Chloroform was one of the best solvents as regards the enantiometic purity (e.p.) of the ester produced. In this solvent, the optimum temperature for the reaction was determined to be 35C. The enzyme exhibited maximum activity at a water content of 13 [plus minus] 2% (w/w). The enantiomeric purity obtained was 83 [plus minus] 2% of (S)-glycidol butyrate and did not depend on the alcohol concentration or the enzyme water content for values of these parameters up to 200 mM and 25% (w/w), respectively. ...

1993-08-05

203

FMRFamide-like immunoreactivity in rat brain: development of a radioimmunoassay and its application in studies of distribution and chromatographic properties  

International Nuclear Information System (INIS)

A radioimmunoassay is described for the molluscan neuropeptide, Phe-Met-Arg-Phe-NH"2(FMRFamide). The antibody used is C-terminal-specific and shows slight but significant (1-2%) cross-reactivity with chicken pancreatic polypeptide (APP). The assay has been used to identify in rat brain extracts a pair of molecules that may represent mammalian counterparts of FMRFamide. Their concentrations were highest in spinal cord and hypothalamus (>10 pmol.g"-_1) and lowest in cerebellum and striatum (<3.5 pmol.g"-_1). The two immunoreactive peptides were separated on CM ion-exchange chromatography where they appeared to be less basic than FMRFamide. On Sephadex G50 gel filtration one eluted in a similar position to FMRFamide and the other slightly earlier suggesting it may be of higher molecular weight. The rat immunoreactive components do not correspond to previously described neuropeptides or hormones, and may be members of a new group of mammalian neuropeptides with ...

204

Clinical evaluation of serum ferritin to iron ratio in malignant diseases  

Energy Technology Data Exchange (ETDEWEB)

Serum ferritin levels were measured in 72 normal subjects and in 214 cases with various diseases by an immunoradiometric assay. In normal subjects, the serum ferritin levels were 27-230 ng/ml. Elevated serum ferritins were observed in most cases with iron excess and acute hepatitis. Markedly elevated levels were found in the majority of cases with acute leukemia, malignant lymphoma, hepatoma, and pancreatic cancer. High ferritin levels were also found in other malignant diseases. However, the range overlapped broadly with that of nonmalignant diseases. The serum ferritin correlated significantly with serum iron in normals and in those with iron deficiency anemia. In most nonmalignant cases, the serum ferritin and iron levels distributed on a regression line obtained from levels in normals and those with iron deficiency anemia. However, 92% of the malignant cases showed a serum ferritin to iron ratio higher than that of normal subjects. The estimation of the serum ...

1981-07-01

205

Renovation of Isogo thermal power plant of Electric Power Development Co. with new and old systems near to each other; Dengen Kaihatsu (kabu) Isogo karyoku hatsudensho koshin koji shinsetsu hosui kanro to kisetsu hatsudensho OF cable no kinsetsu seko  

Energy Technology Data Exchange (ETDEWEB)

This is a build-and-scrap-and-build job, in which a new No. 1 generator is constructed while the existing plant stays in operation in the same site. Since interference between the new and the existing systems are unavoidable in such work, protection is sufficiently provided and measurements are frequently performed when the work comes to involve important structures positioned close to each other, such as the existing No. 1 and No. 2 OF (oil-filled) cables transmitting power from the existing power plant to Minami-Yokohama Substation of Tokyo Electric Power Co., Ltd., and the newly planned discharge channel or the existing covered sewerage and the newly planned discharge outlet. Now that the newly planned discharge channel intercepts the OF cables at three places and is installed to pass under the existing cable duct, it once happened that the duct supporting piles were severed for the cables to suspend in the air though temporarily. During ...

1998-09-05

206

Radiotherapy and multimodality management of cholangiocarcinoma  

International Nuclear Information System (INIS)

Purpose: To evaluate the results of radiotherapy in cholangiocarcinoma patients managed with various combinations of chemotherapy and surgical resection with selective liver transplantation. Methods and Materials: From January 1990 to December 1995, 61 patients with histologically confirmed biliary duct adenocarcinoma were seen in the Radiation Oncology Department of the University of Pittsburgh. Median follow-up was 22 months (1 to 91 months). The extent of surgery was complete resection in 23 patients (including 17 with orthotopic liver transplant), partial resection in 4, and biopsy in 34. All patients had radiotherapy; median dose was 49.5 Gy. Thirty patients received chemotherapy: 5-fluorouracil (5-FU)-leucovorin with interferon alpha (IFN#alpha#) in 27, and taxol in 3. Results: The median survival was 20 months (95% CI 15-25 months). The 5-year actuarial survival was 23.8 #+-# 6.8%. The only significant variable in multivariate analysis was achieving a ...

1999-04-01

207

Peripheral cholangiocarcinoma : three-phase helical CT appearance  

International Nuclear Information System (INIS)

To analyze the enhancement patterns and morphology of peripheral cholangiocar-cinomas (CCs), as seen on three-phase helical CT. Three-phase helical CT scans of 25 cases of 24 patients with pathologically-proven CCs were retrospectively reviewed. After intravenous administration of contrast media, scans of the hepatic arterial phase (HAP) were obtained at 30 seconds, of the portal venous phase (PVP) at 70 seconds, and of the delayed phase (DP) at 3 minutes. Linear, dense, marginal enhancement was seen in 17 CCs (68%), mainly on HAP images (64%) while thick, band-like, peripheral enhancement was seen in 18 (72%), on either PVP (52%) or DP (44%). Internal enhancement was observed in 23 CCs (92%) on PVP (68%) and/or DP (88%), and 19 CCs (76%) among them showed incomplete enhancement of stippled and/or septated patterns. Most (76%) were seen throughout all three phases to be hypoattenuating, as compared to the surrounding parenchyma. On HAP, wedge-shaped parenchymal enhancement was ...

1997-08-01

208

PFB coal fired combined cycle development program. Commercial plant requirements definition update (Task 1. 1)  

Energy Technology Data Exchange (ETDEWEB)

The Coal Fired Combined Cycle (CFCC) power system thermodynamic cycle is illustrated schematically. Pressurized air supplied at the discharge of gas turbine compressors is ducted to the pressure vessel of pressurized, fluidized-bed, combustor-steam generator modules. The air is introduced in parallel to the beds, entering through distribution grids beneath each bed. Steam generation tubes are buried within the beds and are also arranged as membrane tube walls enclosing the four sides. Crushed coal (1/4 inch x 0) is pneumatically fed at locations just above the air inlet grids at the bottom of each bed. Dolomite is similarly fed to the individual beds. The coal is burned at a temperature below the ash fusion point. Sulfur is removed in the fluid beds through reaction of the SO/sub 2/ with CaCO/sub 3/ and O/sub 2/ to form solid CaSO/sub 4/ and CO/sub 2/ gas. The combustion gases leave the beds at a temperature in the range of 1400/sup 0/F to 1750/sup 0/F, depending ...

1980-05-01

209

Use of the ADINA (Automatic Dynamic Incremental Nonlinear Analysis) computer code on a COSA II (Computer Codes for Salt) benchmark computer case of the local area - progress report 1990  

International Nuclear Information System (INIS)

The COSA II (computer codes for salt) benchmark problem has been pursued with the ADINA (Automatic Dynamic Incremental Nonlinear Analysis) program code. With the use of this, the code should be validated by means of experimental data and the ability to reproduce real-life calculation results of the KfK (Kernforschungszentrum Karlsruhe/Nuclear Research Center in Karlsruhe) should be proven. A successful validation of the code then forms the foundation stone for the ability to use different calculation problems in the final (ultimate) storage. This also accompanies the consequent reaction of replacing the STEALTH (Solids and Thermal Hydraulics Code for EPRI Adapted from LAGRANGE TOODY and HEMP) program which has a number of program-specific weaknesses compared to the ADINA computer code. In order to reproduce the approximate values from the KfK, the same values have been used. Differences were evident in the discretion and the selection of the initial values for ...

210

The economic geology of clays/shales raw materials for the ceramics industry in Lebanon  

International Nuclear Information System (INIS)

Author.Field, laboratory and market studies are a must for proper evaluation of natural resources for the mineral industry of lebanon. Sites selectively convenient to the existing major Lebanese ceramics industry centered in the Beqa'a region, were investigated as to their geology, geography and economic character. The raw materials are shales, mud stones, siltstones and other argillaceous rocks of Jurassic to Cretaceous age coming from selective sites in south and central Lebanon. The finished products include wall, floor, roofing tiles, pipes, sanitary ware, pottery and brick specimens. Differential thermal analysis, scanning electron microscopy, firing and physico-chemical tests and analyses characterized the raw materials into two major groups: the suitable are siliceous argillaceous rocks and unsuitable calcareous argillaceous rocks. The suitable group is divided into two varieties. The first is dominantly a disordered Kaolinite with low drying and firing ...

211

Physical mechanisms of transient enhanced dopant diffusion in ion-implanted silicon  

Energy Technology Data Exchange (ETDEWEB)

Implanted B and P dopants in Si exhibit transient enhanced diffusion (TED) during annealing which arises from the excess interstitials generated by the implant. In order to study the mechanisms of TED, transmission electron microscopy measurements of implantation damage were combined with B diffusion experiments using doping marker structures grown by molecular-beam epitaxy (MBE). Damage from nonamorphizing Si implants at doses ranging from 5{times}10{sup 12} to 1{times}10{sup 14}/cm{sup 2} evolves into a distribution of {l_brace}311{r_brace} interstitial agglomerates during the initial annealing stages at 670{endash}815{degree}C. The excess interstitial concentration contained in these defects roughly equals the implanted ion dose, an observation that is corroborated by atomistic Monte Carlo simulations of implantation and annealing processes. The injection of interstitials from the damage region involves the dissolution of {l_brace}311{r_brace} defects during Ostwald ripening with an ...

1997-05-01

212

Physical mechanisms of transient enhanced dopant diffusion in ion-implanted silicon  

International Nuclear Information System (INIS)

Implanted B and P dopants in Si exhibit transient enhanced diffusion (TED) during annealing which arises from the excess interstitials generated by the implant. In order to study the mechanisms of TED, transmission electron microscopy measurements of implantation damage were combined with B diffusion experiments using doping marker structures grown by molecular-beam epitaxy (MBE). Damage from nonamorphizing Si implants at doses ranging from 5x10"1"2 to 1x10"1"4/cm"2 evolves into a distribution of #left brace#311#right brace# interstitial agglomerates during the initial annealing stages at 670 endash 815 degree C. The excess interstitial concentration contained in these defects roughly equals the implanted ion dose, an observation that is corroborated by atomistic Monte Carlo simulations of implantation and annealing processes. The injection of interstitials from the damage region involves the dissolution of #left brace#311#right brace# defects during Ostwald ripening with an activation ...

213

Intrahepatic peripheral cholangiocarcinoma; dynamic features of CT scans  

International Nuclear Information System (INIS)

To elucidate the dynamic features of CT scans in peripheral cholangiocarcinoma for the differentiation of this tumor from various primary hepatic neoplasms. Materials were 24 cases of pathologically confirmed peripheral cholangiocarcinoma. Contrast enhancement patterns of central and peripheral portion of the masses were analyzed at three phases including arterial dominant(22), tissue equilibria(24), and postequilibria(9). Other associated CT findings and laboratory data were analyzed. Serum total bilirubin was mostly below 2 mg/dl(22/24), hepatitis B surface antigen was positive in only 9%, serum alphafetoprotein was elevated in 18%, carcinoembryonic antigen in 47%, cancer antigen 19-9 in 60%. In the arterial dominant image(22), 50% of the cases showed peripheral hyperdensity and 50% total hypodensity. In the tissue equilibrial images(24), 63% showed total hypodensity, 25% peripheral hyperdensity, and 13% total isodensity. In the postequilibrial images(9), 45% showed peripheral ...

1995-05-01

214

Frontopolar and anterior temporal cortex activation in a moral judgment task. Preliminary functional MRI results in normal subjects  

International Nuclear Information System (INIS)

The objective was to study the brain areas which are activated when normal subjects make moral judgments. Ten normal adults underwent BOLD functional magnetic resonance imaging (fMRI) during the auditory presentation of sentences that they were instructed to silently judge as either 'right' or 'wrong'. Half of the sentences had an explicit moral content ('We break the law when necessary'), the other half comprised factual statements devoid of moral connotation ('Stones are made of water'). After scanning, each subject rated the moral content, emotional valence, and judgment difficulty of each sentence on Likert-like scales. To exclude the effect of emotion on the activation results, individual responses were hemo dynamically modeled for event-related f MRI analysis. The general linear model was used to evaluate the brain areas activated by moral judgment. Regions activated during moral judgment included the frontopolar cortex (FPC), medial frontal gyrus, right ...

2001-09-01

215

Buried soils of Late Quaternary moraines of the Wind River Mountains, Wyoming  

Energy Technology Data Exchange (ETDEWEB)

Buried soils occur on kettle floors of four Pinedale moraine catenas of the western Wind River Mountains of Wyoming. Radiocarbon ages from bulk samples of Ab horizons indicate the soils were buried during the mid-Holocene. Soils on kettle floors have silty A and Bw horizons that overlie buried A and B horizons that also formed in silt-rich sediments. Crests and backslope soils also have A and Bw horizons of sandy loam formed over 2BCb and 2Cb horizons of stony coarse loamy sand. Recent data show the silty textures of the A and B horizons are due to eolian silt and clay from the Green River Basin just west of the mountains. The buried soils appear to represent alternate periods of erosion and deposition on the moraines during the Holocene. The original soils developed on higher slopes of the moraines were eroded during the mid-Holocene and the 2BC and 2C horizons exposed at the surface. Eroded soil sediments were transported downslope onto the kettle floors. Following erosion, silt-rich ...

1992-01-01

216

Turbulent heat transfer augmentation and friction in periodic fully developed channel flows  

Energy Technology Data Exchange (ETDEWEB)

Measurements are presented of the distribution of average friction factors (f) as well as local and average ({ovr Nu}) heat transfer coefficients for fully developed channel flows with two rib-roughened opposite walls. The temperature measurements were made by using both a laser holographic interferometer and thermocouples. In addition, the reattachment length was determined by flow visualization. The Reynolds number (Re) was varied from 5.0 {times} 10{sup 3} to 5.4 {times} 10{sup 4}; the rib pitch-to-height ratios (Pi/H) were 10, 15, 20; and the rib height-to-hydraulic diameter ratios (H/De) were 0.063, 0.081, and 0.106. The detailed results allowed the peaks of heat transfer augmentation and the regions susceptible to hot spots to be located and allowed the relative contribution of the rib surface and the channel wall to the heat transfer augmentation to be determined. Moreover, relative to a smooth duct, the enhancement of both {ovr Nu} and f at various Re, ...

1992-02-01

217

Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice  

British Library Electronic Table of Contents (United Kingdom)

Cholestatic liver injury induced by alpha-naphthylisothiocyanate (ANIT) is provoked by injury to intrahepatic bile ducts and the progression of hepatic necrosis requires the procoagulant protein tissue factor (TF) and extrahepatic cells including neutrophils. Recent studies have shown that myeloid cell TF contributes to neutrophil activation. We tested the hypothesis that myeloid cell TF contributes to neutrophil activation in ANIT-treated mice. TF activity in liver homogenates increased significantly in TF^f^l^o^x^/^f^l^o^x mice treated with ANIT, but not in TF^f^l^o^x^/^f^l^o^x/LysMCre mice (TFD^M^y^e^l^o^i^d mice), which have reduced TF expression in monocytes/macrophages and neutrophils. Myeloid cell-specific TF deficiency did not alter expression of the chemokines KC or MIP-2 but redu...

2011-01-01

218

TPX Neutral Beam Injection System design  

International Nuclear Information System (INIS)

The existing Tokamak Fusion Test Reactor Neutral Beam system is proposed to be modified for long pulse operation on the Tokamak Physics Experiment (TPX). Day one of TPX will call for one TFTR beamline modified for 1000 second pulse lengths oriented co-directional to the plasma current. The system design will be capable of accommodating an additional co-directional and a single counter directional beamline. For the TPX conceptual design, every attempt was made to use existing Neutral Beam hardware, plant facilities, auxiliary systems, service infrastructure, and control systems. This paper describes the moderate modifications required to the power systems, the ion sources, and the beam impinged surfaces of the ion dumps, the calorimeters, the various beam scrapers, and the neutralizers. Also described are the minimal modifications required to the vacuum, cryogenic, and gas systems and the major modification of replacing the beamline-torus duct in its entirety. ...

1993-10-11

219

Study for developing method of repairing interior of duct. Kanro naimen hoshu koho no kaihatsu kenkyu  

Energy Technology Data Exchange (ETDEWEB)

A hose lining process, used widely for underground service structures, such as for city gas, and water and sewerage pipes, was adopted to repair interiors of underground wire raceways, and improvements were made for power cable pipe use, including long size construction, inner diameter assurance, and flame retardation. The sealing hose as a lining material consists of a fabric layer woven by warps of polybutylene terephthalate (PBT) and wefts of combined PBT fibers and glassfibers, the fabric being coated with polyurethane resin on one side. The other side of the fabric is coated with heat hardening resin made of epoxy resin as the main ingredient and aromatic amine as the hardening agent to assure close adhesion of the sealing hose onto the pipe interior. Mimic raceways were used to verify the lining material for its abrasion coefficient, mechanical strength, wear resistance, water cut-off performance, chemical resistance, and shape retention performance against external pressure. ...

1991-03-25

220

Studies on improvement of heat transfer characteristics in high temperature heat exchangers, (1)  

International Nuclear Information System (INIS)

Reported in this paper are the theoretical and experimental studies, with regard to the effects of radiation between walls, conducted for the improvement of heat transfer characteristics of the circular duct in high temperature heat exchangers that operate through the medium of non-radiating gases at around 1,000"0C. To study the fundamental performance of the heat transfer augmentation, the experiment was carried out using a double tube at temperatures up to 900"0C. The outer tube in a double tube was selectively heated so as to give a uniform heat flux selected of 6.5 x 10"3 and 4.6 x 10"4 kcal/m"2.h, while the inner tube was used as a radiating surface to impart the radiation heat transmitted from the outer tube. Selectively preheated air was caused to flow in an annular passage at an inlet temperature selected within 100"0C to 400"0C and with the Reynolds number of 2.9 x 10"3 to 3.5 x 10"4. The heat transfer characteristics were found to improve by 22% to 79% ...

1978-01-01

221

Sampling and chemical analysis of smoke gas components from the SP Industry Calorimeter  

Energy Technology Data Exchange (ETDEWEB)

This report describes the sampling and chemical analyses of smoke gas components for combustion performed in the SP Industry Calorimeter, where continuous measurements of oxygen, carbon dioxide and carbon monoxide are an integrated part of the Calorimeter system. On-line measurements of nitrogen oxides and total amounts of unburnt hydrocarbons were performed. Hydrogen cyanide, hydrogen chloride and ammonia in the smoke were sampled and absorbed in impinger bottles and subsequently analyzed using wet chemical techniques. An adsorbent sampling system was designed to allow the identification and quantitative analysis of individual organic compounds in the smoke. Gas chromatography was utilized with a mass spectrometric detector for the identification and a FID for quantification of the total amounts as well as individual components. A procedure for cleaning the smoke gas duct in between the combustion experiments was designed and found to be effective. The materials ...

1995-12-31

222

Rehabilitation of a gassy low pressure liquid filled 115 kV cable  

Energy Technology Data Exchange (ETDEWEB)

The recent attempt to degassify a self contained liquid filled (SCLF) cable in Ontario Hydro is described. In September 1989, there was a high pressure alarm on one phase of a SCLF 115 kV cable circuit. The direct buried cable circuit is about 1,890 m long with two joints and was installed in 1968. Oil samples from the cable had 10 to 12% gas content with high levels of hydrogen, methane, and ethane, and very low levels of carbon monoxide, carbon dioxide, and acetylene. From these results it was concluded that the gas was generated by low energy electrical discharges and the paper insulation was not degraded. Various utilities and cable manufacturers were contacted to find if they had experienced similar problems. The cable duct oil was flushed and gasified and the successive oil samples were analyzed in order to locate the gassing site. The joints were examined and oil samples were taken through holes drilled in the cable sheath. From the test results the problem ...

1994-12-31

223

Pilot studies at industrial sources with an electrostatic precipitator having wide plate spacing. Pilotuntersuchungen an industriellen Quellen mit einem elektrischen Abscheider grosser Gassenweite  

Energy Technology Data Exchange (ETDEWEB)

With a pilot electrostatic precipitator having wider plate spacings than usual tests were performed under industrial conditions. In the two-section two-duct pilot precipitator with a precipitation area of 60 m/sup 2/ the plate spacing was increased up to 1,000 mm. As gas velocities values between 0.5 and 2.0 m/s were selected. The precipitator was tested with the flue gases of a coal-fired power station and in the room dedustion of an iron ore sintering plant. Starting with a plate spacing of 250 mm increasing the spacing results initially in a small increase of the precipitation rate. After reaching a maximum the rate decreases and finally with passing a critical spacing it goes below the initial value. Dedusting flue gases the spacing with the maximum and the critical spacing depend on the gas velocity. Cost analyses demonstrate that increasing the up to now used plate spacings may led to considerable savings. Depending on the kind of application plate spacings ...

1983-01-01

224

Optimized, Competitive Supercritical-CO_2 Cycle GFR for Gen IV Service  

International Nuclear Information System (INIS)

An overall plant design was developed for a gas-cooled fast reactor employing a direct supercritical Brayton power conversion system. The most important findings were that (1) the concept could be capital-cost competitive, but startup fuel cycle costs are penalized by the low core power density, specified in large part to satisfy the goal of significant post-accident passive natural convection cooling; (2) active decay heat removal is preferable as the first line of defense, with passive performance in a backup role; (3) an innovative tube-in-duct fuel assembly, vented to the primary coolant, appears to be practicable; and (4) use of the S-Co2 GFR to support hydrogen production is a synergistic application, since sufficient energy can be recuperated from the product H2 and 02 to allow the electrolysis cell to run 250 C hotter than the reactor coolant, and the water boilers can be used for reactor decay heat removal. Increasing core power density is identified as ...

225

Oil-filled, multi-core cable with at least one conductor differing from others  

Energy Technology Data Exchange (ETDEWEB)

This patent discloses an oil-filled, multi-core, electric cable having three cores within a metal sheath suitable for underwater applications. Each core has a conductor surrounded by insulation and has substantially the same outer dimensions as the other cores. One conductor is made of copper and has a central oil duct. The other conductors are made of stranded aluminum wires in side-by-side and contacting relation and the ratio of the cross-sectional area of the metal of the copper conductor to the cross-sectional area of the metal of each aluminum conductor is the reciprocal of the ratio of the electrical conductivities thereof. One object of this invention is that of overcoming the drawbacks existing in the known oil-filled, multi-core cables, i.e. to provide cable which, in case of a rupture of the cable sheath, has fairly small leakages of insulating, fluid oil from the cable and at the same time permits a reduction in the weight of the cable for equal power ...

1987-02-03

226

Numerical modeling of slug flow initiation in a horizontal channels using a two-fluid model  

International Nuclear Information System (INIS)

This paper presents a methodology for modeling slug initiation and growth in horizontal ducts. Transient two-fluid equations are solved numerically using a class of high-resolution shock capturing methods. The advantage of this method is that slug formation and growth in a stratified regime can be calculated directly from the solutions to the flow field differential equations. In addition, by using high-resolution shock capturing methods that do not contain numerical diffusion, the discontinuity generated by slugging in the flow field can be modeled with good accuracy. The two-fluid model is shown to be well-posed mathematically only under certain conditions. Under these circumstances, the two-fluid model is capable of correctly predicting and modeling the flow physics. When ill-posed, an unbounded instability occurs in the flow field solution, and the instability amplitude increases exponentially with decreasing mesh sizes. This work shows that there are three ...

2011-02-01

227

Natural convection around a horizontal solid cylinder wrapped with a layer of fibrous or porous material  

International Nuclear Information System (INIS)

Heat losses in duct flow and heat transfer enhancement are investigated through an analysis of natural convection about a horizontal cylinder with a porous or fibrous coating. The porous substrate may be used for two purposes. According to its properties, it may be employed as an insulating material or as a means to surface augmentation. An optimization study is then carried out in order to find the best conditions that allow good thermal insulation or heat transfer rate improvement. The flow motion and heat transfer coefficient are predicted for various conditions. The results show that an efficient insulation which means less than 10% in heat losses is obtained for a porous layer thickness of 0.8x tube diameter and a permeability corresponding to Da #<=# 10"-"7. Nevertheless, there is a Darcy number limit above which convection must be accounted for. Porous or fibrous materials may also be used as a heat transfer augmentation technique. To achieve this goal, ...

2007-06-01

228

Intraoperative electron beam therapy and external photon beam therapy with lumpectomy as primary treatment for early breast cancer  

International Nuclear Information System (INIS)

Between 1984 and 1988, seven women with breast cancer were treated with intraoperative electron beam therapy (IOEBT). All patients were Caucasian. Patient age ranged from 37 to 62 (median 53) years. Histopathology was infiltrating duct carcinoma (6/7) or medullary carcinoma (1/7). Four tumors were staged T1 N0 MO, one T1 N1 MO, one T2 N1 MO, and one lesion was recurrent. At the time of primary lumpectomy or axillary node dissection, a dose of 10 or 15 Gy IOEBT was administered to the tumor bed with 6 or 9 MeV electrons through the lumpectomy wound. All patients received 45 or 50 Gy over five to six weeks with 6 MV photons to the breast and, in four patients, to the regional nodes. Three patients received adjuvant chemotherapy and tamoxifen. No post-operative complications were observed. All patients are alive as of August, 1989, with no evidence of recurrent disease. Excellent cosmesis is the rule. Clinical and technical aspects of treatment are presented along ...

229

Intrahepatic cholangiocarcinoma : gross appearance and corresponding pathologic and radiologic features  

International Nuclear Information System (INIS)

To assess the clinical and pathologic features of each type of intrahepatic cholangiocarcinoma, which is divided into three types according to gross appearance, and to determine the efficacy of CT in detecting this tumor. The pathologic and CT features of 53 surgically proven cases of intrahepatic cholangio-carcinoma were reviewed. On the basis of their gross appearance, the tumors were divided into three types, as follows : mass forming (n=33), periductal infiltrating (n=6), and intraductal growth type (n=14). CT scans were analyzed for sensitivity of detection and correlation between a tumors appearance and its histopathology. The most common histopathologic feature of mass forming and periductal infiltrating type was tubular adenocarcinoma, while in the intraductal growth type, papillary adenocarcinoma (100%) was common. With regard to pattern of tumor spread, intrahepatic and lymph node metastasis were more common in the mass forming and periductal infiltrating type than in the ...

1999-05-01

230

Influence of the inlet velocity profiles on the prediction of velocity distribution inside an electrostatic precipitator  

Energy Technology Data Exchange (ETDEWEB)

The influence of the velocity profile at the inlet boundary on the simulation of air velocity distribution inside an electrostatic precipitator is presented in this study. Measurements and simulations were performed in a duct and an electrostatic precipitator (ESP). A four-hole cobra probe was used for the measurement of velocity distribution. The flow simulation was performed by using the computational fluid dynamics (CFD) code FLUENT. Numerical calculations for the air flow were carried out by solving the Reynolds-averaged Navier-Stokes equations coupled with the realizable k-{epsilon} turbulence model equations. Simulations were performed with two different velocity profiles at the inlet boundary - one with a uniform (ideal) velocity profile and the other with a non-uniform (real) velocity profile to demonstrate the effect of velocity inlet boundary condition on the flow simulation results inside an ESP. The real velocity profile was obtained from the velocity ...

2009-01-15

231

Hepatobiliary scintigraphy in current pediatric practice  

Energy Technology Data Exchange (ETDEWEB)

Hepatobiliary scintigraphy is the only non-invasive technique providing real-time assessment of hepatocytes function and bile progression from the liver to the intestine; for this reason it is of great importance in the study of jaundice and many other disorders of the liver and the biliary tract in children. Ultrasonography is the initial method of evaluating the intra- and extrahepatic bile ducts dilatation: the differential diagnosis between biliary atresia and neonatal hepatitis cannot however be done without hepatobiliary scintigraphy. Cystic fibrosis patients also require hepatobiliary scintigraphy; liver and biliary tract disease can really occur independently of the underlying disease severity and the presence of steatorrhoea. Hepatobiliary imaging in children who have undergone liver transplantation is of major importance; it can assess vascularity, parenchymal function biliary drainage, possible presence of a bile leak and obstruction; it has very good ...

1998-06-01

232

Heat transfer in parallel plate duct with a sinusoidal wave plate uniaxially inserted (1st). Effect of wave length on heat transfer augmentation  

Energy Technology Data Exchange (ETDEWEB)

High-performance heat transfer augmentation methods applicable in the forced convection field of heat exchangers include a method which requires no external drive means, such as the insertion of a turbulence augmentation object into the flow passage and the use of a wave-shaped flow passage, but disturbs the main stream of flow to raise the heat transportation effect thereby to augment heat transfer in the flow passage. The heat transfer characteristics and thermal performance ratio achieved when sinusoidal-shape plates are inserted instead of augmentation objects, such as cylinders, with a high shape-induced resistance were studied. As a result, the relationship between the resistance coefficient, average Nusselt number, heat transfer coefficient, and pitch was clarified. It has been revealed that the use of eddies with a large gap flow and recirculation area should be considered in order to get a higher heat transfer coefficient and a higher thermal performance ratio. 5 references, ...

1988-09-01

233

Guideline for sampling and analysis of 'tars' and particles in biomass producer gases  

Energy Technology Data Exchange (ETDEWEB)

The further development of a Guideline (formerly Protocol) for sampling and analysis of 'tars' from biomass producer gases is reported. This Guideline is being developed as a project within the European Fifth Framework Programme with additional partners from Switzerland and North-America. In this paper an outline and the principle of the Guideline are given. The Guideline is based on isokinetic sampling of particles and 'tar' from the main producer gas duct, particle filtration at high temperature, gas cooling in a liquid quench, 'tar' absorption in a solvent at low temperatures, an optional backup adsorber, and flow measurement and control. The Guideline gives a definition for 'Gravimetric tar' which is the 'tar' number to be determined by the Guideline. Also, the Guideline gives procedures for compound analysis by gas chromatography - mass spectrometry (GC-MS) or gas ...

2000-07-01

234

Evaluation of the effectiveness of an antimicrobial air filter to avoid porcine reproductive and respiratory syndrome virus (PRRSV) aerosol transmission, after 16 months of exposure to a commercial swine environmental conditions  

Energy Technology Data Exchange (ETDEWEB)

The effectiveness of Noveko's antimicrobial filter was evaluated after 16 months of exposure to commercial swine production. The experiment involved the use of a scaled model of a commercial swine facility consisting of 2 small chambers connected by a duct containing the filters. A 5 kg naive pig was placed in the reception chamber for a period of 6 hours after aerosolization with porcine reproductive and respiratory syndrome virus (PRRSV). Blood samples from pigs were collected before and after aerosolization to test for the presence of PRRSV RNA. Only blood samples were tested for PRRSV antibodies by IDEXX 2XR ELISA. None of the 9 pigs tested were found to be infected. The study showed that the technology used to integrate the antimicrobial agent into the filter fibers allows the filter combination to withstand extreme weather and endure commercial swine production for at least 16 months, and can maintain its effectiveness to avoid airborne transmission ...

2010-07-01

235

Evaluation of advanced technologies for power transformers. Final report  

Energy Technology Data Exchange (ETDEWEB)

The high insulating strength of certain gases, such as sulfur hexafluoride, when used at high pressure, suggests that there may be advantages to compressed gases as the insulating fluid in power transformers. However, simply exchanging the oil for compressed gas in an otherwise conventional transformer design will not yield a significant overall advantage. Compressed gases present the engineer with properties which are quite different from mineral oil. If gases are to be used as the major insulating fluid in power transformers, then virtually all aspects of the insulation and cooling of the apparatus must be reconsidered, affording an opportunity to introduce new design concepts, new materials, and new construction techniques. In this program, the feasibility of using the following principal design concepts has been explored: sheet conductors for the windings; a system of sealed, self-contained, annular cooling ducts containing circulating cooling fluid to cool the ...

1981-01-01

236

Economic evaluation of four types of dry/wet cooling applied to the 5-MWe Raft River geothermal power plant  

Energy Technology Data Exchange (ETDEWEB)

A cost study is described which compared the economics of four dry/wet cooling systems to use at the existing Raft River Geothermal Plant. The results apply only at this site and should not be generalized without due consideration of the complete geothermal cycle. These systems are: the Binary Cooling Tower, evaporative condenser, Combin-aire, and a metal fin-tube dry cooling tower with deluge augmentation. The systems were evaluated using cooled, treated geothermal fluid instead of ground or surface water in the cooling loops. All comparisons were performed on the basis of a common plant site - the Raft River 5 MWe geothermal plant in Idaho. The Binary Cooling Tower and the Combin-aire cooling system were designed assuming the use of the isobutane/water surface condenser currently installed at the Raft River Plant. The other two systems had the isobutane ducted to the evaporative condensers. Capital credit was not given to the system employing the direct ...

1982-07-01

237

Dynamic modeling of interfacial structures via interfacial area transport equation  

International Nuclear Information System (INIS)

The interfacial area transport equation dynamically models the two-phase flow regime transitions and predicts continuous change of the interfacial area concentration along the flow field. Hence, when employed in the numerical thermal-hydraulic system analysis codes, it eliminates artificial bifurcations stemming from the use of the static flow regime transition criteria. Accounting for the substantial differences in the transport phenomena of various sizes of bubbles, the two-group interfacial area transport equations have been developed. The group 1 equation describes the transport of small-dispersed bubbles that are either distorted or spherical in shapes, and the group 2 equation describes the transport of large cap, slug or churn-turbulent bubbles. The source and sink terms in the right-hand-side of the transport equations have been established by mechanistically modeling the creation and destruction of bubbles due to major bubble interaction mechanisms. In the present paper, the ...

2005-01-01

238

Development of a 1200 KW/CYL low pressure dual fuel engine for LNG carriers  

Energy Technology Data Exchange (ETDEWEB)

This paper describes the design and feasibility tests of a 570 mm bore 4 stroke low pressure (L.P.) dual fuel engine rated at 20.9 bar BMEP meant for the propulsion of LNG carriers. The basic design features which are to be in accordance with classification societies safety rules are described: individual electro hydraulic valves located in the air manifold ducts, pilot injection, monitoring system etc. The engine capability to burn variable liquid/gas fuel proportions have been investigated with diesel oil and heavy fuel and possible running zones are defined. This ensures the possibility of the engine to cope with the different boil off gas quantity emanating from the ship`s tank during her loaded - and ballast - journeys. With the very lean setting of this engine, no adverse influence of the high ash lube-oil additives were found during the tests. Further tests are necessary to confirm that possible more significant fouling of the combustion chamber is still ...

1998-12-31

239

Development of HT-9 for liquid-metal reactor components  

International Nuclear Information System (INIS)

Alloy HT-9 is being used for both duct and cladding applications in advanced liquid-metal reactor (LMR) experiments. This tempered martensitic steel was selected for use as an LMR core component material primarily because of its excellent resistance to radiation-induced swelling. Experiments conducted in the Fast Flux Test Facility (FFTF) at 410 degree C and exposures in the range of 150 to 175 displacements per atom (dpa) have shown that Ht-9 exhibits only a 0.2 to 0.3% increase in volume. Cold-worked austenitic steels exhibit volumetric increases of 20 to 30% at 410 degree C, Alloy HT-9 is being used for a series of fuel pin experiments in the FFTF, and these tests have achieved a burnup of 175 MWd/kg metal and a fluence of 25 x 10"2"2 n/cm"2 (E > 0.1 MeV) without fuel pin breach. The high confidence placed in HT-9 is based on a wide series of in- and ex-reactor experiments. Test results for these experiments are summarized in this paper.

1989-11-26

240

Combustion of chemical substances. Fire characteristics and smoke gas components in large-scale experiments  

Energy Technology Data Exchange (ETDEWEB)

This report describes the combustion experiments performed using the SP Industry Calorimeter. In addition to measuring parameters such as heat release rate (HRR), mass loss rate, effective heat of combustion and smoke obscuration, considerable effort was put into the characterisation of the smoke gases in order to obtain a basis for evaluations of the toxic potency of the smoke. The materials studied were Nylon 66, polypropene, polystyrene (with and without fire retardant, respectively), PVC and chlorobenzene. A total of 19 large-scale, well ventilated combustions were carried out. The mass of sample burned ranged from 20 kg to 125 kg in an experiment. A procedure was designed for cleaning the smoke gas duct between experiments and was found to be effective. Measurements were carried out for the amounts of O{sub 2}, CO{sub 2}, CO, NO{sub x}, THC (unburned hydrocarbons), HCN, HCl, NH{sub 3} and individual organic compounds in the smoke. Adsorbents were used for the ...

1995-12-31

241

Combined peritoneography and computerized tomography for evaluating abdominal complications in patients undergoing continuous peritoneal dialysis  

International Nuclear Information System (INIS)

Continuous ambulatory peritoneal dialysis (CAPD) is a generally well-tolerated treatment. However, some patients exhibit such complications as to prevent the continuation of treatment. Peritonitis is the major problem, but the continuation of treatment may also be undermined by different complications, such as peritoneal leakage, hernia, catheter malfunctioning, and scrotal-penile edema; a careful investigation of the patient is always needed in such cases. From November 1985 to February 1990, we examined 20 patients, who had presented with different types of complications in the course of dialysis. Peritoneography demonstrated 3 cases of abdominal hernias, 2 cases of patency of the peritoneal-vaginal duct, and 2 cases of catheter obstruction. Peritoneal CT allowed the identification of leakage in 3 patients, while the combined use of the two techniques showed adhesions or pathologic peritoneal recesses in 7 cases. In 3 patients normal patterns were observed. ...

1985-11-01

242

Can magnetospheric electron temperature be inferred from whistler dispersion measurements  

International Nuclear Information System (INIS)

An approximate expression for whistler-mode group velocity is obtained, taking into account the effects of electron temperature and anisotropy, density and ion effects, effects of oblique propagation and a non-dipolarity of the dayside magnetospheric magnetic field. This expression is applied to the propagation of whistlers between one hemisphere and the other. It is pointed out that at frequencies close to the upper cut-off of whistler spectra, perturbations to whistler group delay times due to temperature effects can be of the same order of magnitude as, or even higher than, the corresponding perturbations due to finite electron density and ion effects. A method of magnetospheric electron temperature diagnostics is proposed and applied to two whistlers recorded at Halley (L = 4.3). It is pointed out that the values of temperature obtained from the analysis of whistler spectra depend on the choice of model of electron density and temperature distribution in the magnetosphere and on ...

243

C-106 tank process ventilation test  

Energy Technology Data Exchange (ETDEWEB)

Project W-320 Acceptance Test Report for tank 241-C-106, 296-C-006 Ventilation System Acceptance Test Procedure (ATP) HNF-SD-W320-012, C-106 Tank Process Ventilation Test, was an in depth test of the 296-C-006 ventilation system and ventilation support systems required to perform the sluicing of tank C-106. Systems involved included electrical, instrumentation, chiller and HVAC. Tests began at component level, moved to loop level, up to system level and finally to an integrated systems level test. One criteria was to perform the test with the least amount of risk from a radioactive contamination potential stand point. To accomplish this a temporary configuration was designed that would simulate operation of the systems, without being connected directly to the waste tank air space. This was done by blanking off ducting to the tank and connecting temporary ducting and an inlet air filter and housing to the recirculation system. This configuration ...

1998-07-20

244

Self-expandable polytetrafluoroethylene (PTFE)-covered nitinol stent for the palliative treatment of malignant biliary obstruction  

Energy Technology Data Exchange (ETDEWEB)

We wanted to determine the technical and clinical efficacy of placing a self-expandable PTFE-covered nitinol stent for the management of inoperable malignant biliary obstruction. Thirty six patients with inoperable malignant biliary obstructions were treated by placement of self-expandable PTFE-covered nitinol stents (S and G Biotech Corporation, Seongnam, Korea). Clinical evaluation was done with assessment of the serum bilirubin and alkaline phosphatase levels, which were measured before and after stent placement within 1 week, at 1 month and at 3 months. The patient survival rate and stent patency rate were calculated with performing Kaplan-Meier survival analysis. Successful stent placement was achieved in all the patients without procedure-related complication. Pancreatitis as an early complication occurred in two cases. The serum bilirubin and alkaline phosphatase levels were significantly decreased after the procedure. During the follow-up, recurrent ...

2008-06-15

245

Palliative hepatic intraarterial chemotherapy (HIC) using a novel combination of gemcitabine and mitomycin C: results in hepatic metastases  

International Nuclear Information System (INIS)

To evaluate repeated hepatic intraarterial chemotherapy (HIC) as a palliative treatment option for unresectable cholangiocarcinoma and liver metastases of various origins that were progressive under systemic chemotherapy. Between 2002 and 2006, 55 patients were treated in 4-week intervals (mean five sessions). Combined gemcitabine/mitomycin was administered intraarterially within 1 h. Tumor response was evaluated after the third session according to RECIST. Treated tumor entities were colorectal carcinoma (CRC) (n = 12), breast cancer (BC) (n = 12), cholangiocarcinoma (CCC) (n = 10), pancreatic (n = 4), ovarian (n = 3), gastric, cervical, papillary (each n = 2), prostate, esophageal carcinoma, leiomyosarcoma (each n = 1), cancer of unknown primacy (CUP) (n = 5). All patients tolerated the treatment well without any major side effects or complications. In total, there were 1 complete response (CR), 19 partial responses (PR), 19 stable (SD) and 16 progressive ...

2008-03-01

246

Malignant duodenal obstructions: palliative treatment with covered expandable nitinol stent  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the feasibility and clinical effectiveness of using a polyurethane-covered expandable nitinol stent in the palliative treatment of malignant duodenal obstruction. Under fluoroscopic guidance, a polyurethane-covered expandable nitinol stent was placed in 12 consecutive patients with malignant duodenal obstructions. All presented with severe nausea and recurrent vomiting. The underlying causes of obstruction were duodenal carcinoma (n=4), pancreatic carcinoma (n=4), gall bladder carcinoma (n=2), distal CBD carcinoma (n=1), and uterine cervical carcinoma (n=1). The sites of obstruction were part I (n=1), part II (n=8), and III (n=3). Due to pre-existing jaundice, eight patients with part II obstructions underwent biliary decompression prior to stent placement. An introducer sheath with a 6-mm outer diameter and stents 16 mm in diameter were employed, and to place the stent, and after-loading technique was used. Stent placement was technically successful in ...

2002-04-01

247

Four cases of solid pseudopapillary tumors of pancreas: Imaging findings and pathological correlations  

Energy Technology Data Exchange (ETDEWEB)

Objective: Solid pseudopapillary tumor of the pancreas (SPTP tumor) is a rare pancreatic neoplasm with low malignant potential, which usually affects female patients in the second or third decades of life. It is a non-functional, slow-growing neoplasm that very often reaches considerable size before the first symptoms appear. Symptomatology is frequently related to tumor size. Surgical excision is usually curative in most cases. Infrequently the tumor can appear in male patients or in aged women, which can make the diagnosis more difficult. Some patients develop liver metastases in the follow-up that can be resected. Our purpose is to review the radiological and pathological findings of SPTP with emphasis on these infrequent cases. Subjects and methods: The medical records and radiological findings of patients who underwent surgery for SPTP between 2000 and 2005 were retrospectively reviewed. Study eligibility required that patients had undergone surgical resection ...

2006-04-15

248

Four cases of solid pseudopapillary tumors of pancreas: Imaging findings and pathological correlations  

International Nuclear Information System (INIS)

Objective: Solid pseudopapillary tumor of the pancreas (SPTP tumor) is a rare pancreatic neoplasm with low malignant potential, which usually affects female patients in the second or third decades of life. It is a non-functional, slow-growing neoplasm that very often reaches considerable size before the first symptoms appear. Symptomatology is frequently related to tumor size. Surgical excision is usually curative in most cases. Infrequently the tumor can appear in male patients or in aged women, which can make the diagnosis more difficult. Some patients develop liver metastases in the follow-up that can be resected. Our purpose is to review the radiological and pathological findings of SPTP with emphasis on these infrequent cases. Subjects and methods: The medical records and radiological findings of patients who underwent surgery for SPTP between 2000 and 2005 were retrospectively reviewed. Study eligibility required that patients had undergone surgical resection ...

2006-04-01

249

Carcinogenicity of Black Rock Harbor sediment to the eastern oyster and trophic transfer of Black Rock Harbor carcinogens from the blue mussel to the winter flounder  

Energy Technology Data Exchange (ETDEWEB)

The eastern oyster (Crassostrea virginica) developed neoplastic disorders when experimentally exposed both in the laboratory and field to chemically contaminated sediment from Black Rock Harbor (BRH), Bridgeport, Connecticut. Neoplasia was observed in oysters after 30 or 60 days of continuous exposure in a laboratory flow-through system to a 20 mg/L suspension of BRH sediment plus postexposure periods of 3, 30, or 60 days. Composite tumor incidence was 13.6% for both exposures. Tumor occurrence was highest in the renal excretory epithelium, followed in order by gill, gonad, gastrointestinal, heart, and embryonic neural tissue. Regression of experimental neoplasia was not observed when the stimulus was discontinued. In field experiments, gill neoplasms developed in oysters, deployed in cages for 30 days at BRH and 36 days at a BRH dredge material disposal area in Central Long Island Sound, and kidney and gastrointestinal neoplasms developed in caged oysters deployed 40 days in Quincy ...

1991-01-01

250

10% low density corn-oil emulsion oral contrast agent for abdominal computed tomography  

Energy Technology Data Exchange (ETDEWEB)

CT of the gastrointestinal tract is commonly performed after administration of a high-density diluted iodinated oral contrast material. However, because if inadequate mixing of the contrast material with the gastrointestinal contents, pseudotumor and poor mucosal visualization are frequently shown on abdominal CT. To overcome these problem, 10% corn oil emulsion (COE) is tested as an alternative oral contrast agent in 40 patients. We analyse patients tolerance, gastric mucosal visualization and discrimination of pancreas from the duodenal C-loop to 10% COE in 40 patients compared with those obtained from 35 patients, who was received high-density diluted iodinated oral contrast agent (gastrografin). The results are as follows : 1. Patients' tolerance to 10% COE is similar to that to conventional oral contrast agent. 2. Image of the gastric mucosa from patients receiving 10% COE is superior to that receiving oral contrast agent. 3. The discrimination between ...

1990-10-15

251

10% low density corn-oil emulsion oral contrast agent for abdominal computed tomography  

International Nuclear Information System (INIS)

CT of the gastrointestinal tract is commonly performed after administration of a high-density diluted iodinated oral contrast material. However, because if inadequate mixing of the contrast material with the gastrointestinal contents, pseudotumor and poor mucosal visualization are frequently shown on abdominal CT. To overcome these problem, 10% corn oil emulsion (COE) is tested as an alternative oral contrast agent in 40 patients. We analyse patients tolerance, gastric mucosal visualization and discrimination of pancreas from the duodenal C-loop to 10% COE in 40 patients compared with those obtained from 35 patients, who was received high-density diluted iodinated oral contrast agent (gastrografin). The results are as follows : 1. Patients' tolerance to 10% COE is similar to that to conventional oral contrast agent. 2. Image of the gastric mucosa from patients receiving 10% COE is superior to that receiving oral contrast agent. 3. The discrimination between ...

1990-10-01

252

Computed tomography of the mediastinal lesion  

Energy Technology Data Exchange (ETDEWEB)

Authors retrospectively analyzed the CT findings of mediastinal lesions in surgically or clinically confirmed 37 cases at Kosin Medical College during recent 4 years from September 1979 to August 1983. 1. Among 37 caes, malignant lymphoma were 7 cases, thymoma and vascular lesion or anomaly were 5 cases respectively, benign teratoma and tuberculous mediastinal lymphadenitis and neurogenic tumor were 4 cases respectively, pericardial cyst were 2 cases, bronchogenic cyst, non-specific cyst, pancreatic pseudocyst, mesothelioma, Bochdalek hernia was 1 case respectively. 2. The sex ratio between male and female was about 1 : 1 and the majority of the patients with malignant lymphoma and teratoma was under 20 years old. 3. CT findings of the each mediastinal lesion. 1) Primary mediastinal malignant lymphoma. (1) A large, matted, continuous and midline-crossing mass was observed in the superior and the anterior mediastinums in all cases. (2) In 3 cases, irregular lower ...

1984-09-15

253

Transluminal radio-frequency thermal ablation using a stent-type electrode: an experimental study  

Energy Technology Data Exchange (ETDEWEB)

To assess the feasibility of transluminal radiofrequency thermal ablation using a stent-type electrode and to determine, by means of in-vivo and in-vivo animal studies, the appropriate parameters. In-vivo: the radiofrequency electrode used was a self-expandable nitinol stent with 1cm insulated ends. A stent was placed in the portal vein of bovine liver, and ablations at target temperatures of 70, 80, 90, and 100 .deg. C were performed. Ablated sizes were measured longitudinally. In vivo: four mongrel dogs were anesthetized, and a stent was inserted in the common bile duct under fluoroscopic guidance through an ultrasound-guided gall bladder puncture site. The ablation temperature was set at 80 .deg. C, and each dog underwent proximal and distal esophageal ablations lasting 12 minutes. They were sacrificed immediately. In-vivo: ablated sizes showed significant correlation with target temperatures (r>0.04; p<0.05). Although most lesions were fusiform, ...

2003-06-01

254

Selection and Creep Property of Alloy 617 for the IHX Application  

Energy Technology Data Exchange (ETDEWEB)

Since the very high temperature reactor (VHTR) components such as hot gas ducts and intermediate heat exchanger (IHX) are operated during a design life of 30 to 60 years at 950 .deg. C and 3-8MPa in He impurities, their components are required to have good high temperature strength, creep-rupture strength, high temperature stability, and good corrosion resistance. Among them, creep properties are the most important, because the integrity of their components should be preserved during a design life of over 30 years at the maximum operating temperature up to 1000 .deg. C. So far, there are no materials approved by ASME III which is a nuclear code for temperatures reaching 1000 .deg. C, and until now, a material selection is still left as a key issue. Some leading candidate alloys can be selected from the high temperature materials approved by ASME VIII. Alloy 617 is considered as a prospective material for the IHX because it has an excellent combination of a high ...

2007-07-01

255

Introducing DeBRa: a detailed breast model for radiological studies  

Energy Technology Data Exchange (ETDEWEB)

Currently, x-ray mammography is the method of choice in breast cancer screening programmes. As the mammography technology moves from 2D imaging modalities to 3D, conventional computational phantoms do not have sufficient detail to support the studies of these advanced imaging systems. Studies of these 3D imaging systems call for a realistic and sophisticated computational model of the breast. DeBRa (Detailed Breast model for Radiological studies) is the most advanced, detailed, 3D computational model of the breast developed recently for breast imaging studies. A DeBRa phantom can be constructed to model a compressed breast, as in film/screen, digital mammography and digital breast tomosynthesis studies, or a non-compressed breast as in positron emission mammography and breast CT studies. Both the cranial-caudal and mediolateral oblique views can be modelled. The anatomical details inside the phantom include the lactiferous duct system, the Cooper ligaments and the ...

2009-07-21

256

Expression of Na(+)-H+ exchange and ATP-dependent proton extrusion in growing rat IMCD cells  

Energy Technology Data Exchange (ETDEWEB)

As the last step of urinary acidification, the inner medullary collecting duct (IMCD) is thought to secrete protons into the tubular lumens by means of a H(+)-translocating adenosinetriphosphatase (H(+)-ATPase). However, recent studies have also shown the existence of Na(+)-H+ exchange activity in IMCD cells. Although the physiological function of the antiporter in IMCD cells is unknown, activation of Na(+)-H+ exchange in other cell-culture systems has been suggested to be closely associated with the process of cell growth. Thus presence of Na(+)-H+ exchange may relate to the growth phase of these cells. To examine intracellular pH (pHi) regulation in growing IMCD cells, we studied proton transport by Na(+)-dependent and Na(+)-independent mechanisms by microfluorimetry using the pHi-sensitive dye 2',7'-bis(carboxyethyl)-5,6-carboxyfluorescein acetoxymethyl ester (BCECF/AM). Actively growing cells, defined by (3H)thymidine incorporations, ...

1990-03-01

257

Experiences in radioactive gaseous effluent management in JAERI  

International Nuclear Information System (INIS)

In the Japan Research Reactor-II (JRR-2), the main source of _4_1Ar generation is the exhaust air from the horizontal experimental holes and the pneumatic tubes. For the horizontal experimental holes, the flow of exhaust air through the holes was decreased by improving the airtightness, and a decay duct of capacity 2.4 m_3 was installed in the middle of the exhaust line. In consequence, the release rate of _4_1Ar was reduced by 6-8%. For the pneumatic tubes, a mechanical shutter was installed in the tube. The shutter stops the exhaust air flow, except when the pneumatic tube is used. Prior to the use, the activated air in the tube is led to a decay tank. As a result, the _4_1Ar release rate was reduced by 10-20%. By the above means, the yearly exposure at the site boundary was reduced to 0.36 mR from 2.6 mR. In Hot Laboratory for metallurgical examination of spent fuel, the exhaust filtration system consists of filters in the cave, i.e. frame trap, prefilter, HEPA ...

1983-05-01

258

Estimated costs of ventilation systems complying with the HUD ventilation standard for manufactured homes  

Energy Technology Data Exchange (ETDEWEB)

At the request of the US Department of Housing and Urban Development (HUD), the Pacific Northwest Laboratory estimated the material, labor, and operating costs for ventilation equipment needed for compliance with HUD`s proposed revision to the ventilation standard for manufactured housing. This was intended to bound the financial impacts of the ventilation standard revision. Researchers evaluated five possible prototype ventilation systems that met the proposed ventilation requirements. Of those five, two systems were determined to be the most likely used by housing manufacturers: System 1 combines a fresh air duct with the existing central forced-air system to supply and circulate fresh air to conditioned spaces. System 2 uses a separate exhaust fan to remove air from the manufactured home. The estimated material and labor costs for these two systems range from $200 to $300 per home. Annual operating costs for the two ventilation systems were estimated for 20 US ...

1993-11-01

259

Energy use in swine unit in the finishing system with waste treatment; Uso de energia em unidade suinicola em sistema de terminacao com tratamento de residuos  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to assess the energy flux and energetic balance related to the swine production and the recycling of residues generated by the system for utilization as organic fertilizers. The experiment was carried out at Vale dos Ipes Farm, located in the city of Ouro Verde do Oeste, in the Western of Parana State. One finishing phase swine unity containing 600 animals was monitored from January to June 2005. The treatment system is composed by one steel digester with capacity for 50 m{sup 3}, one sedimentation tank, one algae tank and one bio fertilizer storage tank. The swine barn cleaning is performed by dry scratching on a daily basis. The generated residues flow by gravitation through ducts towards the digester. The duration of the hydraulic retention period was 12 days. In the calculation of energetic efficiency, the energetic component ration is the greatest energetic cost in production system of finishing phase swine, corresponding to 95% ...

2006-07-01

260

Dynamic modeling of interfacial structures via interfacial area transport equation; Modelisation dynamique des structures d'interface via l'equation de transport de l'interface  

Energy Technology Data Exchange (ETDEWEB)

The interfacial area transport equation dynamically models the two-phase flow regime transitions and predicts continuous change of the interfacial area concentration along the flow field. Hence, when employed in the numerical thermal-hydraulic system analysis codes, it eliminates artificial bifurcations stemming from the use of the static flow regime transition criteria. Accounting for the substantial differences in the transport phenomena of various sizes of bubbles, the two-group interfacial area transport equations have been developed. The group 1 equation describes the transport of small-dispersed bubbles that are either distorted or spherical in shapes, and the group 2 equation describes the transport of large cap, slug or churn-turbulent bubbles. The source and sink terms in the right-hand-side of the transport equations have been established by mechanistically modeling the creation and destruction of bubbles due to major bubble interaction mechanisms. In the present paper, the ...

2005-07-01

261

Correct diagnosis of vascular encasement and longitudinal extension of hilar cholangiocarcinoma by four-channel multidetector-row computed tomography  

International Nuclear Information System (INIS)

Accurate diagnosis of local invasion of hilar cholangiocarcinomas is challenging due to their small size and the anatomic complexity of the hepatic hilar region. On the other hand, the correct diagnosis of local invasion is essential for assuring the possibility of curative surgery. The purpose of this study was to evaluate the feasibility of four-channel multidetector-row computed tomography (MDCT) in the assessment of vascular and bile duct involvement, by which we could obtain useful information for the surgical management of hilar cholangiocarcinoma. The subjects were 18 patients for whom the extent of tumor invasion was surgically and pathologically confirmed. All patients underwent preoperative multiphasic CT scanning by MDCT. Arterial and portal dominant phases were acquired using a detector configuration of 1.25 mm x 4 mm, and both axial and multiplanar reconstructed images were interpreted. Longitudinal extension was evaluated up to second-order branches. ...

2009-01-01

262

Imaging-based dust sensors: equipment and methods  

Science.gov (United States)

Dust detection and control in real time, represent one of the most challenging problem in all those environments where fine and ultrafine airborne particulate solids products are present. The presence of such products can be linked to several factors, often directly related and influenced by the working-production actions performed. Independently from the causes generating dust, airborne contaminants are an occupational problem of increasing interest as they are related to a wide number of diseases. In particular, airborne dusts are well known to be associated with several classical occupational lung diseases, such as the pneumoconiosis, especially at high levels of exposure. Nowadays there is also an increasing interest in other dust related diseases, from the most serious as cancer and asthma, to those related with allergies or irritation and other illnesses, also occurring at lower levels of exposure. Among the different critical factors influencing health risk for airborne dust ...

2004-05-01

263

Dynamic modeling of interfacial structures via interfacial area transport equation  

Energy Technology Data Exchange (ETDEWEB)

Full text of publication follows:In the current thermal-hydraulic system analysis codes using the two-fluid model, the empirical correlations that are based on the two-phase flow regimes and regime transition criteria are being employed as closure relations for the interfacial transfer terms. Due to its inherent shortcomings, however, such static correlations are inaccurate and present serious problems in the numerical analysis. In view of this, a new dynamic approach employing the interfacial area transport equation has been studied. The interfacial area transport equation dynamically models the two-phase flow regime transitions and predicts continuous change of the interfacial area concentration along the flow field. Hence, when employed in the thermal-hydraulic system analysis codes, it eliminates artificial bifurcations stemming from the use of the static flow regime transition criteria. Therefore, the interfacial area transport equation can make a leapfrog improvement in the ...

2004-07-01

264

Comparison and Physical Interpretation of MCNP and TART Neutron and Gamma Monte Carlo Shielding Calculations for a Heavy-Ion ICF System  

Energy Technology Data Exchange (ETDEWEB)

For heavy-ion beam driven inertial fusion ''liquid-protected'' reactor designs such as HYLIFE-II, a mixture of molten salts made of F{sup 10}, Li{sup -6}, Li{sup 7} and Be{sup 9} (called flibe) allows small chambers and final-focus magnets closer to the target with superconducting coils suffering higher radiation damage, though they can stand only a certain amount of energy deposited before quenching. This work has been primarily focusing on verifying that total energy deposited by fusion neutrons and induced gamma rays remain under such limit values and the final purpose is the optimization of the shielding of the magnetic lens system from the points of view of the geometrical configuration and of the physical nature of the materials adopted. The system is analyzed in terms of six geometrical models going from simplified up to much more realistic representations of a system of 192 beam lines, each focused by six magnets. A 3-D transport calculation ...

2002-07-01

265

Glass Furnace Combustion and Melting Research Facility.  

Energy Technology Data Exchange (ETDEWEB)

The need for a Combustion and Melting Research Facility focused on the solution of glass manufacturing problems common to all segments of the glass industry was given high priority in the earliest version of the Glass Industry Technology Roadmap (Eisenhauer et al., 1997). Visteon Glass Systems and, later, PPG Industries proposed to meet this requirement, in partnership with the DOE/OIT Glass Program and Sandia National Laboratories, by designing and building a research furnace equipped with state-of-the-art diagnostics in the DOE Combustion Research Facility located at the Sandia site in Livermore, CA. Input on the configuration and objectives of the facility was sought from the entire industry by a variety of routes: (1) through a survey distributed to industry leaders by GMIC, (2) by conducting an open workshop following the OIT Glass Industry Project Review in September 1999, (3) from discussions with numerous glass engineers, scientists, and executives, and (4) during visits to ...

2004-08-01

266

The biodistribution and effect on hepatic parenchyma with intraarterial injected I-131 lipiodol into hepatic artery  

Energy Technology Data Exchange (ETDEWEB)

Iodized oil has been used as a contrast agent in lymphangiography. One of the commercially available compounds is Lipidol Ultra-fluid(LUF) which contains 38% iodine by weight. Nakakuma et al(1979) reported that LUF was selectively retained in the hypervascular hepatocellular carcinoma when injected directly into the ligated hepatic artery. Since that time, it has been widely utilized in the detection as well as the therapeutic attempts of hepatocellular carcinoma, where it has been mixed with chemotherapeutic agents or labeled with radioactive I-131. Like all significant advances, the mechanism of lipid retention within the hepatocellular carcinoma is not clearly understood, and also there is a lack of information about the biodistribution and kinetics of I-131 Lipiodol. The apparent safety of this technique require confirmation. The present study was aimed to assess the biodistribution and kinetics of intraarterially injected I-131 Lipiodol and the histologic changes in canine livers. ...

1989-08-15