WorldWideScience
1

Incidental brain lesions on MRI in the depressive elderly  

Energy Technology Data Exchange (ETDEWEB)

The study was designed to determine the correlation between parenchymal lesions on MRI and depression. Thirty patients with depression satisfying the following criteria were selected: (1) 60 years or over at the time of MRI scanning, (2) no evidence of cerebrovascular disorder or dementia, and (3) no evidence of neurological findings such as extremity palsy. Seventy six patients with no history of psychiatric visits to a clinic served as controls. There was no significant difference in risk factors for cerebrovascular disorders, such as hypertension, diabetes mellitus, and ischemic heart disease, between the depressive group and the control group. MRI manifestations were semiquantitatively scored according to the periventricular hyperintensity (PVH), white matter hyperintensity (WMH), and pons hyperintensity (PH). All of the PVH score, WMH score, and cerebral enlargement index ...

1994-07-01

4

Role of MRI in the diagnostic evaluation of parotid diseases  

International Nuclear Information System (INIS)

MRI findings in 13 patients with monolateral parotid tumor were compared with US, sialographic and CT findings. MRI did not allow an accurate diagnosis in 2 patients with diffuse chronic parotitis. MRI was superior to CT in 1 case in defining the intraglandular site of the lesion, and in 2 patients in showing the extraglandular involvement. MRI proved to be superior to CT thanks to its contrast resolution and to multiplanar imaging. MRI high contrast resolution made it possible to demonstrate neoplastic lesions of 4 mm in diameter. The lesion has low signal intensity on T1-weighted images and high signal intensity on T2-weighted. Parotid tumors cannot be characterized by signal intensity alone: only morphology allows to discriminate between benign and malignant lesions. To conclude, US is a screening method, while MRI is ...

1988-01-01

5

MRI in preoperative evaluation of chronic paranasal sinusitis - a comparison with CT  

International Nuclear Information System (INIS)

Purpose: To determine the value of MRI in the preoperative evaluation of chronic paranasal sinusitis and to compare the results with CT and intraoperative findings. Method/Materials: 42 patients with clinical signs of chronic paranasal sinusitis underwent MRI after CT evaluation on one day, with subsequent functional endoscopic sinus surgery on the next day. Coronary CT was obtained with 5-mm slices and table-feed in the prone position, while MRI was performed in the supine position with coronary T_2-TSE+pd and coronary and transverse HASTE, each with 5-mm slice thickness. Aquisition time in MRI was less than 8 minutes. Two radiologists reviewed the CT and MRI scans for signs of sinusitis and detection of anatomical landmarks. The results were correlated with the intraoperative findings. Results: MRI offered no artifacts ...

2001-04-01

6

The Effect of Graded Recession and Anteriorization on Unilateral Superior Oblique Palsy  

UK PubMed Central (United Kingdom)

PurposeWe wanted to examine the effect of graded recession and anteriorization of the inferior oblique muscle on patients suffering from unilateral superior oblique palsy.MethodsInferior...Full Text Available

2006-09-01

7

Sacral haemangioma as a cause of coccydynia  

International Nuclear Information System (INIS)

We report a 55-year-old woman with coccydynia due to a sacral mass. The histological diagnosis was haemangioma. The MRI findings and the unusual location of this lesion are discussed. (orig.)

1998-08-01

8

Magnetic resonance imaging in human lymphodemas  

International Nuclear Information System (INIS)

The MRI's of 16 patients with either primary or secondary lymphatic disorders are evluated and the findings are compared to those from lymphangioscintigraphy or surgery. (author).

1989-09-02

9

MRI of the foetal brain  

International Nuclear Information System (INIS)

Ultrasound examinations for foetal brain abnormalities have been a part of the routine antenatal screening programme in the UK for many years. In utero brain magnetic resonance imaging (MRI) is now being used increasingly successfully to clarify abnormal ultrasound findings, often resulting in a change of diagnosis or treatment plan. Interpretation requires an understanding of foetal brain development, malformations and acquired diseases. In this paper we will outline the technique of foetal MRI, relevant aspects of brain development and provide illustrated examples of foetal brain pathology.

2007-04-01

10

The role of MRI in the diagnosis of recurrent/persistent carpal tunnel syndrome: A radiological and intra-operative correlation  

British Library Electronic Table of Contents (United Kingdom)

MRI (Magnetic resonance imaging) has been widely used in the diagnosis of primary carpal tunnel syndrome (CTS). However, it has had limited clinical application in diagnosing persistent or recurrent CTS. We aimed to investigate the efficacy of this imaging modality in patients who had previously undergone open carpal tunnel release without relief of symptoms, and assess the correlation of MRI with intra-operative findings upon re-exploration. MRI studies were performed on 17 wrists (16 patients) presenting with recurrent/persistent symptoms and signs of CTS in whom repeat nerve conduction studies were also performed. Surgical re-exploration was undertaken on 16 wrists in which a 100% correlation was noted between MRI and intra-operative findings of an incompletely released or re-grown tran...

2011-01-01

11

Computed tomography and magnetic resonance imaging of acquired abnormalities of the inner ear and cerebello-pontine angle  

International Nuclear Information System (INIS)

CT and MRI of acquired abnormalities of the inner ear and cerebello-pontine angle present themselves with very typical findings. The imaging should be adapted to the pathology looked for and either CT or MRI should be used alone or in combination.CT, especially high resolution CT (HRCT), provides an excellent bone contrast, while MRI has a much superior soft tissue contrast. Acute inflammatory changes of the inner ear are solely depicted by contrast-enhanced MRI. HRCT excellently depicts osseous changes of the inner ear and cerebellopontine angle such as chronic ossifying labyrinthitis occurring after acute labyrinthitis, otosclerotic or traumatic changes. Tumorous changes not yielding to bony changes are best delineated by MRI. Posttraumatic hemorrhage and chronic fibrotic changes within the labyrinth are depicted by MRI, only. In ...

2003-03-01

12

An availability of brain magnetic resonance imaging (MRI) in the early diagnosis of latent hepatic encephalopathy  

Energy Technology Data Exchange (ETDEWEB)

Brain MRI was carried out in patients with chronic liver diseases. No abnormal findings were recognized in patients with chronic viral hepatitis, while 59.2% of cirrhotics showed a symmetrically strong signal in basal ganglia on T1 weighted image in MRI. This finding significantly related with lowered Fischer`s ratio of serum amino acid, increased levels of serum phenylalanine, tyrosine and hyaluronic acid, prolonged prothrombin time and decreased platelet counts in the peripheral blood. Overt hepatic encephalopathy was observed in 6 of 34 patients with the strong signal in MRI during follow-up period, while none of patients without that finding developed hepatic encephalopathy. These results have indicated that the strong signal in basal ganglia on MRI appears in cirrhotic patients with severe liver dysfunction, and it is an useful index in ...

1996-03-01

13

Intrasphenoid cephalocele: MRI in two cases  

Energy Technology Data Exchange (ETDEWEB)

The intrasphenoid form of basal cephalocele is uncommon. We describe the clinical, CT and MRI findings in two cases presenting in middle age with persistent cerebrospinal fluid rhinorrhoea. Emphasis is placed upon the imaging findings which aid in discrimination of intrasphenoidal cephalocele from more common causes of a sphenoid sinus mass. (orig.)

1999-07-01

14

Cystic lesions of the seminal vesicles. Demonstration by MRI. Zystische Raumforderungen der Samenblasen. Darstellung mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

Between October 1990 and March 1991, 8 patients with cystic lesions in the region of the posterior bladder wall, the seminal vesicles and the prostate were examined by MRI. In all cases there was accurate characterisation of the lesion and of its anatomy. In 3 patients with abnormalities in the retrovesical space there was very good agreement with the operative findings. 4 patients were treated conservatively. In these patients there was good agreement with the findings on cystoscopy, CT and sonography. (orig.).

1992-07-01

15

Pre-operative MRI of anorectal anomalies in the newborn period  

Energy Technology Data Exchange (ETDEWEB)

Nine infants (six boys, three girls) with anorectal anomalies were examined in the immediate newborn period, prior to corrective surgery, with MRI. Three high, one intermediate and five low anomalies were found at MRI - one patient with a `low` lesion was subsequently found at surgery 2 months later to have a high anorectal anomaly. This infant had passed meconium per urethram soon after the MRI study, prompting the need for a protective colostomy and stressing the importance of a thorough clinical examination of babies with anorectal malformations. The MRI results and findings at surgery were in agreement in all other patients (n=8). Hydronephrosis was evident in two and renal agenesis in one patient. Sacrococcygeal hypoplasia was found in two and two hemivertebrae in one infant. No spinal cord lesion was identified. One fistula was evident on MRI but four were ...

1995-11-01

16

Functional MRI of the pharynx in obstructive sleep apnea (OSA) with rapid 2-D flash sequences  

International Nuclear Information System (INIS)

Functional imaging of the pharynx used to be the domain of cineradiography, CT and ultrafast CT. The development of modern MRI techniques led to new access to functional disorders of the pharynx. The aim of this study was to implement a new MRI technique to examine oropharyngeal obstructive mechanisms in patients with obstructive sleep apnea (OSA). Sixteen patients suffering from OSA and 6 healthy volunteers were examined on a 1.5 T whole-body imager ('Vision', Siemens, Erlangen Medical Engineering, Germany) using a circular polarized head coil. Imaging was performed with 2D flash sequences in midsagittal and axial planes. Patients and volunteers were asked to breathe normally through the nose and to simulate snoring and the Mueller maneuver during magnetic resonance imaging (MRI). Prior to MRI, all patients underwent an ear, nose and throat (ENT) examination, functional fiberoptic nasopharyngoscopy and ...

17

MRI survival guide  

International Nuclear Information System (INIS)

The book is a German translation of an American textbook with the original title ''MRI Survival Guide'' and is intended to serve as an introductory guide for beginners or a reference book for quick information. Readers will find information on the fundamentals of the technology and methodology of MRI as well as all details of relevance to practice in a precise and easy-to-grasp arrangement, covering all anatomic areas of interest, illustrations and descriptions of characteristic signs of pathologic processes, high-quality and unusually large-sized diagnostic pictures, a modern didactic concept for quick orientation, including surveys, tables, and reproductions for visualisation of contents. (orig./CB)

18

Sequential changes in the femoral head after intracapsular fracture of the femoral neck. MRI findings  

International Nuclear Information System (INIS)

Authors obtained T1-weighted MRI images of the femoral head after fracture of the femoral neck and classified the signals into four patterns to investigate the sequential changes of the femoral head. The T1-weighted MRI images obtained initially after femoral neck fracture showed a normal pattern in 10 of the 15 hip joints studied. MRI images obtained subsequently still showed the normal signal pattern in eight of the 10 hip joints which had shown the normal pattern in the first MRI, while two of the 10 joints subsequently showed a band pattern. The joint with the homogeneous pattern in the first MRI subsequently showed a band pattern. Of the three joints with an inhomogeneous pattern in the first MRI, two joints showed a subsequent band pattern, and the other a normal pattern. The joints which showed a band pattern continued to show a similar band pattern. ...

1998-07-01

19

Dynamic enhanced MRI of the subacromial bursa: correlation with arthroscopic and histological findings  

Energy Technology Data Exchange (ETDEWEB)

Objective: To assess dynamic MRI with Gd-DTPA enhancement for evaluating inflammatory changes in the subacromial bursa. Design and patients: We detected the signal intensity changes in dynamic MRI of the subacromial bursa, and confirmed these macroscopically by arthroscopy and histologically. The signal intensity was measured using built-in software, and the enhancement ratio (E ratio) was calculated from dynamic MR images. In addition, as a parameter of the rate of the increase in the signal intensity from 0 to 80 s, the mean increase per second in the E ratio was obtained as the coefficient of enhancement (CE). The correlation was studied of the E ratio and CE with the arthroscopic findings (redness, villous formation, thickening and adhesion), and of the E ratio and CE with the histological findings (capillary proliferation, papillary hyperplasia, fibrosis and inflammatory cell infiltration) of the ...

2003-09-01

20

Staging of osteochondritis dissecans of the knee and ankle with MRI. Comparison with conventional radiography and arthroscopy  

International Nuclear Information System (INIS)

A prospective study was performed on 50 patients suffering from osteochondritis dissecans of the knee and ankle to define criteria for stability and fixation of osteochondral lesions. Morphological parameters in MRI (size, fragmentation, cartilage, interface) and conventional radiology (separation, fragmentation) were registered and compared with arthroscopical staging. MRI staging based on different types of interfaces was demonstrated on T_1- and T_2-weighted images. MRI could correctly predict a Grade 1 lesion in 50%, a Grade 2 lesion in 90%, a Grade 3 lesion on 0%, and a Grade 4 lesion in 79%. Stable lesions were differentiated from unstable lesions in 90%. Radiographic findings corresponded with arthroscopic staging in only 56% of the cases because fibrotic connection may guarantee stability in case of bony separation. (orig./MG).

21

MRI imaging of fetal neck masses with airway compromise: utility in delivery planning  

International Nuclear Information System (INIS)

We present two cases of fetal neck masses that were initially diagnosed by ultrasound and further evaluated with prenatal MRI. MRI findings aided in further delineating the neck masses, increasing confidence in the final diagnosis (cervical teratoma and cystic hygroma). With the fetal airway typically filled with fluid that is of high signal on T2-weighted sequences, MRI images in three planes could identify whether the fetal larynx and trachea were partially or completely compressed by the neck tumor. This information was particularly useful in determining if a controlled delivery such as ex utero intrapartum treatment (EXIT) was necessary and aided the surgeons in planning their approach to establishing airway control in the delivery room. (orig.)

2001-10-01

22

Magnetic resonance imaging findings in 46 elbows with a radial head fracture  

UK PubMed Central (United Kingdom)

Background and purposeRadial head fractures are common, and may be associated with other injuries of clinical importance. We present the results of a standard additional MRI scan...Full Text Available

2010-06-01

23

MRI Findings of Pericardial Fat Necrosis: Case Report  

UK PubMed Central (United Kingdom)

Pericardial fat necrosis is an infrequent cause of acute chest pain and this can mimic acute myocardial infarction and acute pericarditis. We describe here a patient with the magnetic resonance imaging...Full Text Available

2011-05-01

24

Imaging of membranous dysmenorrhea  

Energy Technology Data Exchange (ETDEWEB)

Membranous dysmenorrhea is an unusual clinical entity. It is characterized by the expulsion of huge fragments of endometrium during the menses, favored by hormonal abnormality or drug intake. This report describes a case with clinical, US, and MRI findings before the expulsion. Differential diagnoses are discussed. (orig.)

2001-06-01

25

A wide spectrum of clinical and brain MRI findings in patients with SLC19A3 mutations  

UK PubMed Central (United Kingdom)

BackgroundSLC19A3 (solute carrier family 19, member 3) is a thiamin transporter with 12 transmembrane domains. Homozygous or compound heterozygous mutations in SLC19A3 cause...Full Text Available

26

The role of high-resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) in the diagnosis of preoperative and postoperative complications caused by acquired cholesteatomas  

International Nuclear Information System (INIS)

The role of high-resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) in the diagnosis of preoperative and postoperative complications caused by acquired cholesteatomas will be described in this paper. The pre- and postoperative imaging of the temporal bone was performed with HRCT and MRI. HRCT and MRI were performed in the axial and coronal plane. MRI was done with T2 weighted and T1 weighted sequences both before and after the intravenous application of contrast material. All imaging findings were confirmed clinically or surgically. The preoperative cholesteatoma-caused complications depicted by HRCT included bony erosions of the ossicles, scutum, facial canal in the middle ear, tympanic walls including the tegmen tympani, and of the labyrinth. The preoperative cholesteatoma-caused complications depicted by MRI included signs indicative ...

2003-03-01

27

Childhood neuroborreliosis: clinicoradiological correlation  

Energy Technology Data Exchange (ETDEWEB)

We report the cranial CT and MRI findings in three children with Lyme disease (neuroborreliosis). The neuroimaging findings in children have been rarely reported. We found cranial MRI far superior to cranial CT. Ring-enhancing lesions have been described in acute disseminating encephalomyelitis and multiple sclerosis but not in neuroborreliosis. Although other infectious and inflammatory diseases cannot be excluded, Lyme disease should be included in the differential diagnosis and put forward as being the most likely diagnosis in the appropriate clinical setting. Gadopentetate dimeglumine is helpful in assessing the response to antibiotic treatment. (orig.)

1995-10-01

28

Diagnostic value of MRI for hepatic hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Objective: To investigate the value of MRI in the diagnosis of hepatic hilar cholangiocarcinoma. Methods: Sixty-four patients with hepatic hilar cholangiocarcinomas confirmed by surgery or pathology underwent MRI using a 1.5-T superconductive MR system including conventional unenhanced MRI, MRCP and dynamic contrast-enhanced MRI with Gd-DTPA. Results: Dilatation of the intrahepatic biliary tree with narrowing, occlusion or filling defects in the hepatic hilar bile ducts was noted in all 64 cases. Unenhanced MR[ showed T_1- and T_2-hyperintense hilar masses in 42 patients and was normal in the remaining 22 patients. The hilar masses demonstrated slow, progressive and delayed enhancement patterns. There was enhancement of the thickened bile duct wall with luminal narrowing in the 22 patients without hilar masses. Conclusion: The characteristic MRI findings of ...

2010-02-01

29

MRI findings of the brain in high-voltage electrical burn patient: case report  

Energy Technology Data Exchange (ETDEWEB)

We report the delayed sequelae arising in a case of electrical injury, reviewing the literature on the subject and focusing on the MRI findings of the brain. A 23-year-old male suffered burns to the left parietal scalp, both feet, and the anterior chest wall. Neurological symptoms and MRI abnormalities appeared 14 days after the insult and continued for about three months. T1-weight MR images demonstrated homogeneous hypointensity, while T2-weighted images depicted hyperintense finger-like projections. Contrast-enhanced T1-weighted images demonstrated strong band-like enhancement, indicating meningeal hyperemia. Follow-up MR imaging showed that the lesion had disappeared, indicating that the cerebral edema and meaningeal hyperemia were reversible.

2003-05-01

30

MRI in the diagnosis of non-compacted ventricular Myocardium (NCVM) compared to echocardiography  

International Nuclear Information System (INIS)

Purpose: To report the detection of con-compacted ventricular myocardium (NVCM) with MRI compared to echocardiography in 8 patients. Material and methods: Non-compaction of the ventricular myocardium is a congenital disorder characterized by an altered structure of the myocardial wall resulting from an intrauterine arrest in endomyocardial embryogenesis. The morphological findings consist of a prominent meshwork of multiple myocardial trabeculations and deep intertrabecular recesses, communicating with the left ventricular cavity. 8 consecutive patients (mean age 7.3 years) with clinical and echocardiographic signs of NCVM were examined by MRI (1.5 T, Vision, Siemens) in short axis and 2- and 4-chamber views, using T_1-weighted TSE and Cine-GRE in 6 patients and true FISP sequences in 2 patients. MRI and echocardiography were evaluated for visibility, signs of NCVM and involvement of myocardial wall ...

2003-09-01

31

Nodular fasciitis: correlation of MRI findings and histopathology  

Energy Technology Data Exchange (ETDEWEB)

Objective: To compare the histopathology of nodular fasciitis (NF) with the magnetic resonance imaging (MRI) findings in order to evaluate the basis of the MR signal characteristics. Design and patients: Ten patients with NF, nine females and 1 male, with an age ranging from 13 to 58 years (mean 26.8 years) were studied. MRI findings, available in all 10 patients, were compared with the histopathology in nine patients, and an area-to-area comparative study of the whole specimen section histopathology and MRI was performed in two patients. Results: On the basis of an excisional biopsy or resection specimen, the nine lesions were classified into myxoid (n=4), cellular (n=3) and fibrous (n=2) subtypes. Four myxoid lesions with a subcutaneous location showed a homogeneous SI comparable with muscle on T1-weighted images, high SI on T2-weighted images, and had homogeneous enhancement. One ...

2002-03-01

32

Soft tissue manifestations of early rheumatic disease. Imaging with MRI  

International Nuclear Information System (INIS)

The aim of this study was to evaluate typical magnetic resonance imaging (MRI) findings in early rheumatic diseases manifesting at the soft tissues of the hand using a retrospective analysis. A total of 186 MRI examinations of patients with clinical suspicion of a rheumatic disease were evaluated in a consensus reading by two experienced radiologists. All imaging patterns were assessed with respect to their type and localization. Under blinded and non-blinded conditions diagnoses were correlated with final clinical diagnosis. The most frequent diagnoses were rheumatoid arthritis (RA, 45.7%) and psoriatic arthritis (PsA, 15.6%). The mean correlation between clinical and MRI diagnosis (r) was 0.75 in blinded and 0.853 in non-blinded reading (p <0.001). The following extra-articular imaging patterns were found: synovitis (59.1%), tendovaginitis (91.4%), dactylitis (14.5%), and bone marrow edema (18.3%). ...

2006-08-01

33

MRT of the abdomen in combination with enteroclysis in Crohn disease with oral and intravenous Gd-DTPA  

International Nuclear Information System (INIS)

60 patients between 17 and 72 years of age were investigated. First, an enteroclysis was performed in typical manner. The applicated methylcellulosis was blended with positive oral MR contrast media (Magnevist oral, Schering). After enteroclysis, MRI of the abdomen was performed using T1- and T2-weighted breathhold sequences (Flash 2D pre- and postcontrast and TSE) in axial and coronal planes. The length of the affected bowel and the stenosis seen with enteroclysis correlated well with the visible thickening of the small bowel wall and the stenosis seen in MRI. Using MRI, additional findings could be obtained in 28 patients, such as fistulas, abscesses or a hydronephrosis, or a better assessment of the stenosis was possible with MRI, because of the avoidance of overshadowing of the affected bowel loop with MRI. A brilliant MR-tomographic imaging of the small ...

34

MRI, CT, sonography and thallium-technetium subtraction scintigraphy for the detection of parathyroid disease: a four-year experience  

International Nuclear Information System (INIS)

Sonography, subtraction scintigraphy, computed tomography and MRI were compared in 100 patients who had surgery 105 times for hyperparathyroidism (HPT). Surgical and pathological data were available for all operations. A total of 105 MR, 77 CT, 84 sonograms and 70 subtraction scintigrams were performed. The ability of the imaging modalities, individually and in combination, to detect HPT, histology, size, concomitant thyroid disease and location of the diseased glands has been evaluated. For primary HPT, sensitivity ranged from 68% for MRI to 40% for scintigraphy but was much lower for tertiary HPT with all modalities. The ability to identify diseased glands was strongly size dependent for all methods. If patients had had previous neck surgery, the most sensitive methods were MRI and scintigraphy and this also held true for patients with concomitant thyroid disease and ectopically located glands. The ...

35

MR imaging and MR cholangiopancreatography in the preoperative evaluation of hilar cholangiocarcinoma: correlation with surgical and pathologic findings  

International Nuclear Information System (INIS)

The primary aim was to evaluate delayed contrast-enhanced MRI in depicting perineural spread of hilar cholangiocarcinoma (CCC) and consequently to determine the capability of MRI/MRCP for staging CCC. Fifteen patients that underwent MRI/MRCP and surgical treatment were retrospectively included. Two radiologists evaluated MR images to assess delayed periductal enhancement, extent of bile duct stenosis, liver parenchymal and vascular involvement and presence of liver atrophy. An agreement between delayed enhancement of the bile duct walls and perineural neoplastic spread showed a very good correlation factor (0.93). The overall accuracy in detecting biliary neoplastic invasion was higher for delayed T1-weighted images (93.3%) than for the MRCP images (80%), and T1-delayed image increased the MR accuracy in assessing the neoplastic resectability (p < 0.05). MRI correctly predicted vascular involvement ...

2008-10-01

36

MR findings of primary Ewing's sarcoma of greater wing of sphenoid  

International Nuclear Information System (INIS)

Primary Ewing's sarcoma of the skull is a very rare entity. We report MRI findings in a case of Ewing's sarcoma of the greater wing of sphenoid in a 4-year-old patient. Magnetic resonance imaging showed markedly heterogenous signal intensity with areas of haemorrhage and necrosis. It also demonstrated the exact extent of tumour due to its multiplanar capabilities and was, therefore, helpful in planning surgery. Copyright (2002) Blackwell Science Pty Ltd

2002-12-01

37

Early spondyloarthropathy: scintigraphic, biological, and clinical findings in MRI-positive patients  

British Library Electronic Table of Contents (United Kingdom)

There are no specific diagnostic tests or a gold standard method for measuring disease activity and outcome in spondyloarthropathies (SpA). Many different methods have been developed to assess the signs and symptoms in SpA. The aim of this study was to evaluate the value of scintigraphy, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and Bath Ankilosing Spondylitis Disease Activity Index (BASDAI) in the evaluation of disease activity in early axial SpA diagnosed with magnetic resonance imaging (MRI). Thirty early MRI-positive axial SpA patients (23 males, 7 females) with a median age of 35 (18?55) years and a median duration of inflammatory low back pain of 24 (8?60) months were included in the study. In the patients with sacroiliitis, the sensitivity, specificity, and pos...

2008-01-01

38

Correlation of MRI and histomorphological findings in bone marrow oedema syndrome of the hip  

Energy Technology Data Exchange (ETDEWEB)

In 15 patients (16 hip joints) we found the clinical and radiological signs of BMOS. On T1-weighted MRI images areas of low signal intensity could be observed in the head, neck and the intertrochanteric region of the femur in various extensions. These areas showed a significant increase in signal intensity on the T2-weighted images. Because pain was resistant to conservative therapy all these patients were treated by core decompression of the femoral head in a prospective study. Bone cores were evaluated histologically using undecalcified sections and quantitative microradiography. The existence of intramedullary oedema in exactly the regions exhibiting the MRI pattern of bone marrow oedema was verified histologically; however, bone and marrow changes similar to those of early avascular necrosis (AVN) were also visible. (orig.)

1993-10-01

39

Bilateral lipoma arborescens of the bicipitoradial bursa  

International Nuclear Information System (INIS)

A 37-year-old military mechanic presented to our institution with a chronic history of a slowly enlarging left elbow antecubital fossa mass. There was no history of other chronic illness or trauma. Magnetic resonance imaging (MRI) and excisional biopsy revealed fatty villi and synovial inflammation within the left bicipitoradial bursa, consistent with lipoma arborescens. Four years later the patient presented with a 6-month history of swelling at the antecubital fossa of the opposite elbow. Diagnostic computed tomography and MRI examinations were performed. The surgical and pathologic findings confirmed the imaging diagnosis of lipoma arborescens at the right bicipitoradial bursa. (orig.)

2002-11-01

40

Cranial MRI of neurologically impaired children suffering from neonatal hypoglycaemia  

International Nuclear Information System (INIS)

Background. Metabolic disturbances such as anoxia and hypoglycaemia are important in causing maldevelopment of the neonatal brain. While there have been some pathology studies of the effects of neonatal hypoglycaemia on brain development, reports of MRI findings in such infants have been rare. Objectives. To describe the MRI findings in neurologically handicapped children who had suffered from neonatal hypoglycaemia and to evaluate the relationship between the neurological impairment and neonatal hypoglycaemia. Materials and methods. We retrospectively evaluated the MRI findings in eight full-term infants with neonatal symptomatic hypoglycaemia who later exhibited neurological handicap. The age at which the MRI scans were obtained ranged from 9 months to 8 years 10 months (mean 4 years 1 month, median 4 years). Results. The most striking ...

1999-01-01

41

Glutamate Transporter EAAT2 Expression is Up-Regulated in Reactive Astrocytes in Human Periventricular Leukomalacia  

UK PubMed Central (United Kingdom)

The major neuropathological correlate of cerebral palsy in premature infants is periventricular leukomalacia (PVL), a disorder of the immature cerebral white matter. Cerebral ischemia leading...Full Text Available

2008-05-10

42

An unusual presentation of adenoid cystic carcinoma of the minor salivary glands with cranial nerve palsy: a case study  

UK PubMed Central (United Kingdom)

BackgroundAdenoid Cystic Carcinoma (ACC) is a rare tumor entity and comprises about 1% of all malignant tumor of the oral and maxillofacial region. It is slow growing but a highly...Full Text Available

43

Magnetic resonance appearance of peripheral nerve sheath tumors  

International Nuclear Information System (INIS)

Magnetic resonance imaging (MRI) was used to evaluate 22 histological proven peripheral nerve sheath tumors, approximately two-thirds of which arose in the lower extremity. The histologic distribution was as follows: 12 schwannomas, 7 neurofibromas, and 3 malignant peripheral nerve sheath tumors (2 of which occurred in patients with neurofibromatosis). Most lesions demonstrated an intermediate to moderately bright signal on T_1-weighted images and were minimally inhomogeneous. All lesions were moderately bright on T_2-weighted images, again with variable inhomogeneity. The extent of the tumor was best assessed on proton-density- and T_2-weighted images. Smooth margins were noted in 19 lesions. Of the 3 remaining lesions, 2 were malignant (but had been subjected to biopsy prior to MRI), and the other lesion was a plexiform neurofibroma. MRI accurately determined the relationship between the lesions and the adjacent ...

44

MR imaging of the lateral collateral ligaments after ankle sprain; Aussenbandrupturen des Sprunggelenkes - Darstellung mit der MRT vor und nach funktioneller Therapie  

Energy Technology Data Exchange (ETDEWEB)

35 patients with ankle sprain were examined by MRI and stress radiographs. 13 were operated afterwards, 22 patients underwent a functional conservative therapy and were examined by MRI and stress radiographs and second time after three months. MRI reports were correct in 12 of 13 operated cases. After conservative therapy we did not find any disrupted ankle ligament. MRI showed intact ligaments thickened by scar. (orig./MG) [Deutsch] 35 Patienten mit klinischem Verdacht auf Aussenbandruptur wurden mit der MRT untersucht. 13 Patienten wurden operiert, 22 konzervativ therapiert. Letztere wurden nach drei Monaten erneut mit MRT und gehaltenen Aufnahmen untersucht. Die MRT-Befunde stimmten in 12 von 13 Faellen mit den operativ erhobenen Befunden ueberein. Nach dreimonatiger konzervativer Therapie waren alle 22 Sprunggelenke stabil. Die rupturierten Baender stellten sich verdickt und ...

1995-09-01

45

The Growth of an Extrapancreatic Solid Pseudopapillary Tumor from the Greater Omentum: A Case Report  

Energy Technology Data Exchange (ETDEWEB)

A solid pseudopapillary tumor is an uncommon tumor of the pancreas that rarely metastasizes to other organs and usually shows good prognosis. An extrapancreatic tumor arising from a solid pseudopapillary tumor is very rare. We report a case of an atypical extrapancreatic solid pseudopapillary tumor that arose from the great omentum and disseminated to the peritoneum, and discuss the radiologic findings, including the CT, US, and MRI.

2010-01-15

46

The Growth of an Extrapancreatic Solid Pseudopapillary Tumor from the Greater Omentum: A Case Report  

International Nuclear Information System (INIS)

A solid pseudopapillary tumor is an uncommon tumor of the pancreas that rarely metastasizes to other organs and usually shows good prognosis. An extrapancreatic tumor arising from a solid pseudopapillary tumor is very rare. We report a case of an atypical extrapancreatic solid pseudopapillary tumor that arose from the great omentum and disseminated to the peritoneum, and discuss the radiologic findings, including the CT, US, and MRI

2010-01-01

47

To study the role of dynamic magnetic resonance imaging in assessing the femoral head vascularity in intracapsular femoral neck fractures  

Energy Technology Data Exchange (ETDEWEB)

Intracapsular femoral neck fractures remain unsolved fractures even after improvement in techniques of diagnosis and internal fixation. Individuals who sustain displaced femoral neck fractures are at high risk of developing avascular necrosis and non-union. Although several methods for predicting the viability of femoral head have been reported, they are not effective or widely used because of unreliability, potential complications and technical difficulties. Dynamic MRI was introduced in the recent past as a simple, non-invasive technique to predict the femoral head viability after the femoral neck fractures. In this study role of dynamic MRI was studied in 30 patients with 31 intracapsular femoral neck fractures. Fractures were divided in to three types according to dynamic curve patterns on MRI evaluation and were followed up for 6 months to 2 years to observe the final outcome. Sensitivity, Specificity and the Accuracy ...

2010-09-15

48

To study the role of dynamic magnetic resonance imaging in assessing the femoral head vascularity in intracapsular femoral neck fractures  

International Nuclear Information System (INIS)

Intracapsular femoral neck fractures remain unsolved fractures even after improvement in techniques of diagnosis and internal fixation. Individuals who sustain displaced femoral neck fractures are at high risk of developing avascular necrosis and non-union. Although several methods for predicting the viability of femoral head have been reported, they are not effective or widely used because of unreliability, potential complications and technical difficulties. Dynamic MRI was introduced in the recent past as a simple, non-invasive technique to predict the femoral head viability after the femoral neck fractures. In this study role of dynamic MRI was studied in 30 patients with 31 intracapsular femoral neck fractures. Fractures were divided in to three types according to dynamic curve patterns on MRI evaluation and were followed up for 6 months to 2 years to observe the final outcome. Sensitivity, Specificity and the Accuracy ...

2010-09-01

49

MRI in preoperative evaluation of chronic paranasal sinusitis - a comparison with CT; MRT in der praeoperativen Diagnostik der chronischen Sinusitis im Vergleich mit der CT  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To determine the value of MRI in the preoperative evaluation of chronic paranasal sinusitis and to compare the results with CT and intraoperative findings. Method/Materials: 42 patients with clinical signs of chronic paranasal sinusitis underwent MRI after CT evaluation on one day, with subsequent functional endoscopic sinus surgery on the next day. Coronary CT was obtained with 5-mm slices and table-feed in the prone position, while MRI was performed in the supine position with coronary T{sub 2}-TSE+pd and coronary and transverse HASTE, each with 5-mm slice thickness. Aquisition time in MRI was less than 8 minutes. Two radiologists reviewed the CT and MRI scans for signs of sinusitis and detection of anatomical landmarks. The results were correlated with the intraoperative findings. Results: MRI offered no ...

2001-04-01

50

Magnetic resonance imaging in multiple sclerosis. Imagerie nouvelle par resonance magnetique nucleaire au cours de la sclerose en plaques  

Energy Technology Data Exchange (ETDEWEB)

Magnetic resonance imaging (MRI) has rapidly attained a major position among the examinations used in the diagnostic approach of multiple sclerosis because it is highly sensitive in demonstrating lesions. However, these lesional images may have several meanings, and there is the problem of distinguishing between oedema, which is said to reflect recent lesions, and gliosis which is thought to betray old lesions. The intrinsic MRI parameters studied (i.e. relaxation times) are unable to make this distinction, whereas it is provided by paramagnetic contrast media such as gadolinium. There is no correlation between the changes observed at MRI and the severity of the disease. Another problem is the accuracy of lesion localization, since visualization is predominantly macroscopic. This raises several questions about the demonstration of correlations between clinical signs and site of the lesion(s). At the moment, several teams of ...

1991-09-15

51

The role of high-resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) in the diagnosis of preoperative and postoperative complications caused by acquired cholesteatomas; CT und MRT des erworbenen Cholesteatoms: Prae- und postoperative Bildgebung  

Energy Technology Data Exchange (ETDEWEB)

The role of high-resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) in the diagnosis of preoperative and postoperative complications caused by acquired cholesteatomas will be described in this paper. The pre- and postoperative imaging of the temporal bone was performed with HRCT and MRI. HRCT and MRI were performed in the axial and coronal plane. MRI was done with T2 weighted and T1 weighted sequences both before and after the intravenous application of contrast material. All imaging findings were confirmed clinically or surgically. The preoperative cholesteatoma-caused complications depicted by HRCT included bony erosions of the ossicles, scutum, facial canal in the middle ear, tympanic walls including the tegmen tympani, and of the labyrinth. The preoperative cholesteatoma-caused complications depicted by MRI included signs indicative ...

2003-03-01

52

Usefulness of "1"8F-FDG PET in intrahepatic cholangiocarcinoma  

International Nuclear Information System (INIS)

Surgical resection is the only curative treatment strategy for intrahepatic cholangiocarcinoma (CC). Therefore, accurate staging is essential for appropriate management of patients with CC. We assessed the usefulness of 2-["1"8F]fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) in the staging of CC. We undertook a retrospective review of FDG PET images in 21 patients (10 female, 11 male; mean age 57 years) diagnosed with CC. Ten patients had hilar CC and 11, peripheral CC. Patients underwent abdominal magnetic resonance imaging (MRI) (n=20) and computed tomography (CT) (n=12) for the evaluation of primary tumours, and chest radiography and whole-body bone scintigraphy for work-up of distant metastases. For semi-quantitative analysis, the maximum voxel standardised uptake value (SUV_m_a_x) was obtained from the primary tumour. All peripheral CCs showed intensely increased FDG uptake, and some demonstrated ring-shaped uptake corresponding to ...

2003-11-01

53

Comparison of CT and MRI in patients with tibial plateau fracture: can CT findings predict ligament tear or meniscal injury?  

Energy Technology Data Exchange (ETDEWEB)

(1) To determine the accuracy of computed tomography (CT) in the evaluation of ligament tear and avulsion in patients with tibial plateau fracture. (2) To evaluate whether the presence or severity of fracture gap and articular depression can predict meniscal injury. A fellowship-trained musculoskeletal radiologist retrospectively reviewed knee CT and MRI examinations of 41 consecutive patients presenting to a level 1 trauma center with tibial plateau fractures. Fracture gap, articular depression, ligament tear and footprint avulsions were assessed on CT examinations. The MRI studies were examined for osseous and soft tissue injuries, including meniscal tear, meniscal displacement, ligament tear, and ligament avulsion. CT demonstrated torn ligaments with 80% sensitivity and 98% specificity. Only 2% of ligaments deemed intact on careful CT evaluation had partial or complete tears on MRI. Although the degree of fracture gap ...

2007-02-15

54

Perfusion impairments in children with reactive attachment disorder (RAD) on "9"9"mTc-ECD brain SPECT: comparison with MR findings  

International Nuclear Information System (INIS)

This study aimed to reveal that severe disturbance of attachment relationship with primary care-giver can affect functional and anatomical brain development by measuring cerebral perfusion on "9"9"mTc-ECD brain SPECT and correlative MRI. We included 18 children aged 31 to 76 months who met the diagnostic criteria of RAD as defined in DSM-IV and ICD-10 and SSP and CARS. "9"9"mTc-ECD SPECT was performed using CERASPECT. MRI was performed in all patients. SPECT data were visually assessed. 15 of 18 children had abnormal perfusion on SPECT, revealing decreased perfusion of Lt.thalamus (7/15) and Rt.thalamus (3/15), and bilateral thalami (5/15). Perfusion of basal ganglia was decreased in 8 children. Decreased perfusion of Lt. parietal area was seen in 2. Whereas, all patients had normal MR findings. Perfusion abnormalities involving thalamus, BG in most children with RAD were found in this study. These results suggest that ...

2002-11-15

55

MR findings of central nervous system involvement in acquired immunodeficiency syndrome patient : a report of two cases  

Energy Technology Data Exchange (ETDEWEB)

Central nervous system (CNS) manifestations in acquired immunodeficiency syndrome (AIDS) patients are an early and common feature. The spectrum of AIDS-related CNS diseases are encephalitis caused by the human immunodeficiency virus(HIV) itself, opportunistic infection, infarct and malignancy. We experienced two cases of CNS involvement in AIDS and they were serologically diagnosed as HIV encephalitis and CNS toxoplasmosis, respectively. In the case of the HIV encephalitis patient, brain MRI showed a non-enhancing lesion with high signal intensity on T2WI and low signal on T1WI and there was no mass effect on the right frontal lobe, periventricular white matter, splenium of the corpus callosum or bilateral basal ganglia. In the other case of CNS toxoplasmosis, MR showed multiple nodular and rim enhanced mass lesions in the right basal ganglia, thalamus and periventricular white matter, which were of low signal intensity on T1WI and of high intensity on T2WI. We ...

1996-10-01

56

Value of contrast-enhanced MRI of breast after silicone implant; Wertigkeit der Kontrastmittelmagnetresonanztomographie der Mamma bei Wiederaufbau mittels Implantat  

Energy Technology Data Exchange (ETDEWEB)

Early recognition of recurrence and work-up of clinically indeterminate lesions may be impaired after reconstruction with silicone implants due to superimposition of the implant or to scarring. This study was undertaken to evaluate the use of contrast-enhanced MRI in patients with silicone implant after breast cancer. Contrast-enhanded MRI was offered to 169 patients. Comparative two- to three-view mammography was also performed in 169 patients, as well as comparative sonography in 144 patients. Conventional imaging and clinical examination detected only 8/13 recurrences, whereas 12/13 were detected by MRI. One recurrence had been visible as a strongly enhancing 2-mm dot in a previous examination (2 years before), but was not called. It was therefore counted as false negative. In addition, multicentricity was detected by MRI alone in two of three cases. MRI correctly diagnosed scar ...

1997-09-01

57

Computed tomography and magnetic resonance imaging of acquired abnormalities of the inner ear and cerebello-pontine angle; CT und MRT erworbener Veraenderungen des Innenohrs und Kleinhirnbrueckenwinkels  

Energy Technology Data Exchange (ETDEWEB)

CT and MRI of acquired abnormalities of the inner ear and cerebello-pontine angle present themselves with very typical findings. The imaging should be adapted to the pathology looked for and either CT or MRI should be used alone or in combination.CT, especially high resolution CT (HRCT), provides an excellent bone contrast, while MRI has a much superior soft tissue contrast. Acute inflammatory changes of the inner ear are solely depicted by contrast-enhanced MRI. HRCT excellently depicts osseous changes of the inner ear and cerebellopontine angle such as chronic ossifying labyrinthitis occurring after acute labyrinthitis, otosclerotic or traumatic changes. Tumorous changes not yielding to bony changes are best delineated by MRI. Posttraumatic hemorrhage and chronic fibrotic changes within the labyrinth are depicted by MRI, only. In ...

2003-03-01

58

An intracranial aspergilloma with low signal on T2-weighted images corresponding to iron accumulation  

Energy Technology Data Exchange (ETDEWEB)

We present a case of cerebral aspergillosis in an immunocompetent patient. The MRI signal characteristics were compared with the histologic findings. Irregular low-signal zones were demonstrated between the wall of the abscess and the central necrosis on T2-weighted images; the pathology specimen revealed concentrated iron in these transitional zones but no hemosiderin. Iron is an essential element for the growth of fungal hyphae. The low-signal zones may represent the areas where there was active proliferation of aspergillus, and the unique location of the low signal may be a helpful imaging characteristic for the diagnosis of an aspergillus abscess. (orig.)

2001-07-01

59

Radiologic findings of extraosseous Ewing's sarcoma  

International Nuclear Information System (INIS)

The purpose of this study is to evaluate the radiologic findings of the extraosseous Ewing's sarcoma. Six patients with pathologically confirmed extraosseous Ewing's sarcoma were retrospectively reviewed. Patients included two men and four women with an average age of 21.5 years (age range 9-48 years). Plain radiographs (six patients), magnetic resonance (MR) images (five patients), computed tomographic (CT) scans (three patients) and whole body scintigraphy (two patients) were reviewed and analyzed. Images were evaluated with regard to lesion location, size, margin, muscle or bone involvement and intrinsic imaging characteristics on CT and MRI. The tumors were located in the thigh (three patients), back (two patients) and upper arm (one patient). The tumors ranged in size from 2.3 cm to 7.5 cm (mean, 5.2 cm), were mainly well circumscribed and showed no evidence of calcification prior to treatment. Margins were well defined in four out of the ...

2005-09-01

60

Hilar cholangiocarcinoma: MR correlation with surgical and histological findings  

International Nuclear Information System (INIS)

Aim: To evaluate magnetic resonance cholangiography (MRC) with high-resolution dynamic gadolinium-enhanced magnetic resonance imaging (MRI) in determining the imaging features of hilar cholangiocarcinoma that relate to tumour extent and influence resectability. Materials and methods: Twenty-six patients that underwent resection were reviewed. Tumour location and extent, lobar atrophy, the degree of portal vein and hepatic artery involvement were recorded. The findings were correlated with surgical and histopathological findings. Results: Biliary assessment was concordant in 14 and discordant in eight of 14 stented and four of 12 non-stented patients. In 63/82 veins and 43/74 arteries results were fully concordant. The mean sensitivity, specificity, positive and negative predictive values (PPV, NPV) in predicting involvement of the main portal vein (MPV) at surgery were 83.3, 100, 100, and 92.5%; of the left main branch of ...

2010-10-01

61

Primary cutaneous Ewing's sarcoma/primitive neuroectodermal tumor manifesting numerous small and huge ulcerated masses: its complete remission by chemotherapy and magnetic resonance imaging findings  

International Nuclear Information System (INIS)

Extraskeletal Ewing's sarcoma (ES) and primitive neuroectodermal tumor (PNET) are widely regarded as clinically and histologically identical tumors which consist of small blue round cells. Extraskeletal ESs/PNETs usually occur in the deep soft tissues of the paraspinal region, chest wall, or lower extremities. However, superficially located cases, so-called cutaneous ESs/PNETs, are exceedingly rare, and the vast majority of the reported cases present as a single small mass. We present magnetic resonance imaging (MRI) findings and clinical course of a unique case of primary cutaneous ES/PNET presenting as numerous huge masses with severe ulceration on them. (orig.)

2010-06-01

63

FDTD ??? ??? 3T MRI? RF ??? ??  

KoreaScience (Korea)

Full Text Available

2000-09-01

66

MRI survival guide; MRT Basiskurs  

Energy Technology Data Exchange (ETDEWEB)

The book is a German translation of an American textbook with the original title ''MRI Survival Guide'' and is intended to serve as an introductory guide for beginners or a reference book for quick information. Readers will find information on the fundamentals of the technology and methodology of MRI as well as all details of relevance to practice in a precise and easy-to-grasp arrangement, covering all anatomic areas of interest, illustrations and descriptions of characteristic signs of pathologic processes, high-quality and unusually large-sized diagnostic pictures, a modern didactic concept for quick orientiation, including surveys, tables, and reproductions for visualisation of contents. (orig./CB) [German] Praktisch jeder Mediziner wird im Laufe seiner Berufstaetigkeit mit der MRT konfrontiert - unabhaengig davon ob in der Radiologie, Orthopaedie, Gynaekologie, Chirurgie, Neurologie ...

1999-07-01

67

MRI of the pancreas: Radiological-pathological correlation; MRT des Pankreas: Radiologisch-pathologische Korrelation  

Energy Technology Data Exchange (ETDEWEB)

The typical MRI features of the most common pancreatic diseases, such as pancreatitis and adenocarcinoma of the pancreas, have been established. However, even in these common pancreatic disorders, MRI correlation with the underlying pathology is limited for clinical reasons. We emphasize MR-pathological correlation of inflammatory and neoplastic pancreatic changes, including pancreatitis, adenocarcinoma, acinar cell carcinoma, rare cystic and solid pancreatic neoplasms, and islet cell tumors. By highlighting the correlation of key pathological features with MR findings, a better understanding of the MR appearance of pancreatic pathology can be provided. In addition, MRI may prove a powerful tool in detection and characterization of pancreatic tumors. (orig.) [Deutsch] Das MR-tomographische Erscheinungsbild von Pankreatitiden und Adenokarzinomen des Pankreas, als den haeufigsten Pankreaserkrankungen, ist ...

1996-05-01

68

The value of high-resolution MR-imaging for the staging of malignant lesions of tongue, pharynx and larynx; Klinische Wertigkeit der hochaufloesenden Magnetresonanztomographie beim Staging von Tumoren der Mundhoehle, des Pharynx und des Larynx  

Energy Technology Data Exchange (ETDEWEB)

In a prospective study 102 patients with malignant tumors of the tongue, oropharynx, hypopharynx, and larynx were staged by means of MRI. Special attention was directed at those tumour extensions that could influence the treatment strategy. The MR findings were correlated with the results of palpation, endoscopy, ultrasound, computerised tomography and histopathological findings. MRI showed a good delineation of pT{sub 2} to pT{sub 4} tumours. However, visualisation of small tumours in the soft palate, the tonsils, the pyriform sinuses and vocal cords was difficult. In conclusion our results suggest that in addition to endoscopy MRI is a valuable tool for the examination of tumours of tongue, oropharynx, hypopharynx and larynx. (orig.) [Deutsch] In einer prospektiven Studie wurden 102 Patienten mit malignen Tumoren der Mundhoehle, des Oro- und Hypopharynx sowie des Larynx mit der ...

1994-02-01

69

MRT of the abdomen in combination with enteroclysis in Crohn disease with oral and intravenous Gd-DTPA; MRT des Abdomens in Kombination mit der Enteroklyse bei Morbus Crohn unter Verwendung von oralem und intravenoesem Gd-DTPA  

Energy Technology Data Exchange (ETDEWEB)

60 patients between 17 and 72 years of age were investigated. First, an enteroclysis was performed in typical manner. The applicated methylcellulosis was blended with positive oral MR contrast media (Magnevist oral, Schering). After enteroclysis, MRI of the abdomen was performed using T1- and T2-weighted breathhold sequences (Flash 2D pre- and postcontrast and TSE) in axial and coronal planes. The length of the affected bowel and the stenosis seen with enteroclysis correlated well with the visible thickening of the small bowel wall and the stenosis seen in MRI. Using MRI, additional findings could be obtained in 28 patients, such as fistulas, abscesses or a hydronephrosis, or a better assessment of the stenosis was possible with MRI, because of the avoidance of overshadowing of the affected bowel loop with MRI. A brilliant MR-tomographic imaging of the small ...

1998-01-01

70

MRI in postoperative assessment of univentricular heart disease: correlation with echocardiography and angiography; MRT in der postoperativen Diagnostik bei funktionell univentrikulaerem Herz: Korrelation zu Echokardiographie und Kardangiographie  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To determine the value of MRI in the postoperativ evaluation of a singular ventricle compared to echocardiography and cardiac catheterization. Materials and methods: Thirty-one patients (range: 6 months to 30 years) with a functional single ventricle following palliative corrective operations. Five patients had a Blalock-Taussig-Shunt, 8 patients a Glenn-Anastomosis and 18 a cavopulmonary shunt (6 with classic Fontan-Circulation, 12 with modified cavopulmonary anastomosis). The results in terms of postoperative morphologic changes were compared to percutaneous echocardiography (31/31) and cardiac catheterization (6/31). Results: Echocardiography, which was performed on all patients, could not visualize the entire length of the tunnel, the Glenn-Anastomosis or the central pulmonary arteries in 70% of the patients due to an inadequate acoustic window. MRI was able to show the entire tunnel in 11/12 patients and the central pulmonary ...

2002-12-01

71

Soft tissue signal abnormality associated with eosinophilic granuloma. Correlation of MR imaging with pathologic findings  

Energy Technology Data Exchange (ETDEWEB)

Six patients with eosinophilic granuloma were studied retrospectively in order to correlate the MRI appearances with the pathology. Ages ranged from 2 years 6 months to 11 years. The bones involved were the humerus, ulna, radius, femur, clavicle and ilium. Plain films, MRI and pathology specimens were obtained. A lytic lesion with indistinct margins, endosteal erosions and periosteal reaction was seen in all cases on plain radiographs. Bone marrow signal was decreased on T1-weighted images and increased on T2-weighted images throughout the bony lesion in all cases. T2-weighted images showed extensive soft-tissue abnormalities suggesting inflammatory changes in four cases. In two cases abnormalities were limited. Extensive changes correlated histologically with an early phase lesion. Localized minor changes were associated with a mid-phase lesion. Inflammatory soft-tissue changes could be associated with eosinophilic granuloma. The size of the ...

1994-09-01

72

Functional MRI of the pharynx in obstructive sleep apnea (OSA) with rapid 2-D flash sequences; Funktionelle MRT des Pharynx bei obstruktiver Schlafapnoe (OSA) mit schnellen 2D-FLASH-Sequenzen  

Energy Technology Data Exchange (ETDEWEB)

Functional imaging of the pharynx used to be the domain of cineradiography, CT and ultrafast CT. The development of modern MRI techniques led to new access to functional disorders of the pharynx. The aim of this study was to implement a new MRI technique to examine oropharyngeal obstructive mechanisms in patients with obstructive sleep apnea (OSA). Sixteen patients suffering from OSA and 6 healthy volunteers were examined on a 1.5 T whole-body imager (`Vision`, Siemens, Erlangen Medical Engineering, Germany) using a circular polarized head coil. Imaging was performed with 2D flash sequences in midsagittal and axial planes. Patients and volunteers were asked to breathe normally through the nose and to simulate snoring and the Mueller maneuver during magnetic resonance imaging (MRI). Prior to MRI, all patients underwent an ear, nose and throat (ENT) examination, functional fiberoptic nasopharyngoscopy and ...

1996-03-01

73

Surgery for acoustic neurinoma treated by gamma-knife radiosurgery. A case report  

Energy Technology Data Exchange (ETDEWEB)

A 52-year-old woman had a history of left hearing loss for 5 years. An acoustic neurinoma with 3.2 cm in diameter was diagnosed and treated with gamma-knife radiosurgery (19 Gy of marginal dose) 1 year and 4 months ago. She developed headache, nausea, and visual disturbance 1 month prior to admission. Slight left facial palsy appeared after radiosurgery. Magnetic resonance imaging demonstrated the tumor with central necrosis in the left cerebellopontine angle cistern, increasing in size to 3.5 cm in diameter, and hydrocephalus. Tumor removal was performed incompletely, because of the fibrous appearance of the tumor and severe adherence with the surrounding cerebellar tissue. Facial palsy did not worsen after surgery. Since the hydrocephalus was not resolved, a right ventriculo-peritoneal shunt was inserted. The clinical course in this case suggests that tumor removal followed by radiosurgery was an approximately effective treatment for large ...

2001-08-01

74

Unsolved problems in the diagnosis and surgical treatment of intramedullary tumors  

Energy Technology Data Exchange (ETDEWEB)

Problems and solutions in the diagnosis and operative treatment were clarified by retrospective evaluation of cases of intramedullary tumor in which MRI and surgery had been performed. The subjects were 16 patients (21-75 years old, mean age: 45 years) whose tumor was surgically removed between 1991 and 1998. MRI was performed preoperatively, and T1-weighted images, T2-weighted images, and enhanced images were obtained. Angiography was also performed in some cases. The histological diagnosis based on the MRI findings before surgery were compared with the pathological diagnosis after the operation. In 9/16 cases (56%), the preoperative histological diagnosis based on the MR images was the same as the pathological diagnosis after the operation. In 8 of the 11 cases (73%) whose images showed clear tumor margins and well shaped the tumor, the tumors were completely removed. The concordance rate between the ...

2001-04-01

75

MRI in the diagnosis of non-compacted ventricular Myocardium (NCVM) compared to echocardiography; MR-Tomographie in der morphologischen Darstellung der isolierten non-compaction des linksventrikulaeren Myokards (NCVM)  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To report the detection of con-compacted ventricular myocardium (NVCM) with MRI compared to echocardiography in 8 patients. Material and methods: Non-compaction of the ventricular myocardium is a congenital disorder characterized by an altered structure of the myocardial wall resulting from an intrauterine arrest in endomyocardial embryogenesis. The morphological findings consist of a prominent meshwork of multiple myocardial trabeculations and deep intertrabecular recesses, communicating with the left ventricular cavity. 8 consecutive patients (mean age 7.3 years) with clinical and echocardiographic signs of NCVM were examined by MRI (1.5 T, Vision, Siemens) in short axis and 2- and 4-chamber views, using T{sub 1}-weighted TSE and Cine-GRE in 6 patients and true FISP sequences in 2 patients. MRI and echocardiography were evaluated for visibility, signs of NCVM and involvement of myocardial ...

2003-09-01

76

Staging of osteochondritis dissecans of the knee and ankle with MRI. Comparison with conventional radiography and arthroscopy; Die Stadienbestimmung der Osteochondrosis dissecans am Knie- und Sprunggelenk mit der MRT. Vergleich mit konventioneller Radiologie und Arthroskopie  

Energy Technology Data Exchange (ETDEWEB)

A prospective study was performed on 50 patients suffering from osteochondritis dissecans of the knee and ankle to define criteria for stability and fixation of osteochondral lesions. Morphological parameters in MRI (size, fragmentation, cartilage, interface) and conventional radiology (separation, fragmentation) were registered and compared with arthroscopical staging. MRI staging based on different types of interfaces was demonstrated on T{sub 1}- and T{sub 2}-weighted images. MRI could correctly predict a Grade 1 lesion in 50%, a Grade 2 lesion in 90%, a Grade 3 lesion on 0%, and a Grade 4 lesion in 79%. Stable lesions were differentiated from unstable lesions in 90%. Radiographic findings corresponded with arthroscopic staging in only 56% of the cases because fibrotic connection may guarantee stability in case of bony separation. (orig./MG) [Deutsch] In einer prospektiven Studie an 50 Patienten mit ...

1995-07-01

77

Advanced MRI Methods for Assessment of Chronic Liver Disease  

UK PubMed Central (United Kingdom)

MRI plays an increasingly important role for assessment of patients with chronic liver disease. MRI has numerous advantages, including lack of ionizing radiation and the possibility of performing...Full Text Available

2009-07-01

79

Comparison of histological findings and parathyroid scintigraphy in hemodialysis patients with secondary hyperparathyroid glands  

International Nuclear Information System (INIS)

The objective of this study was to determine the usefulness of parathyroid scintigraphy in histological estimation for secondary hyperparathyroidism (2HPT) using Tc-99m sestamibi or Tc-99m tetrofosmin. Tc-99m sestamibi (MIBI) and Tc-99m tetrofosmin (Tetro) parathyroid imaging following double-phase study, magnetic resonance imaging (MRI), and ultrasound were performed on 14 patients with 2HPT. All patients underwent parathyroidectomy. The uptake of two tracers in parathyroid areas was compared with the histopathologic findings. Forty-nine parathyroid glands were surgically explored and histologically proven to be hyperplastic. Of these, 42 were diagnosed with nodular type (N-type) hyperplasia, and 7 with diffuse type (D-type) hyperplasia. MIBI and Tetro parathyroid imagings detected 34 and 35 parathyroid glands, respectively. The sensitivity of MIBI was determined to be 76.2% (32/42) for N-type, and 28.6% (2/7) for D-type. The sensitivity of ...

2005-04-01

80

Soft tissue manifestations of early rheumatic disease. Imaging with MRI; Fruehmanifestationen rheumatischer Gelenkerkrankungen an den Weichgewebestrukturen der Hand. Nachweis mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study was to evaluate typical magnetic resonance imaging (MRI) findings in early rheumatic diseases manifesting at the soft tissues of the hand using a retrospective analysis. A total of 186 MRI examinations of patients with clinical suspicion of a rheumatic disease were evaluated in a consensus reading by two experienced radiologists. All imaging patterns were assessed with respect to their type and localization. Under blinded and non-blinded conditions diagnoses were correlated with final clinical diagnosis. The most frequent diagnoses were rheumatoid arthritis (RA, 45.7%) and psoriatic arthritis (PsA, 15.6%). The mean correlation between clinical and MRI diagnosis (r) was 0.75 in blinded and 0.853 in non-blinded reading (p <0.001). The following extra-articular imaging patterns were found: synovitis (59.1%), tendovaginitis (91.4%), dactylitis (14.5%), and bone marrow edema ...

2006-08-15

83

Magnetic resonance imaging in acute intractional tuberculosis  

International Nuclear Information System (INIS)

We reported three cases of acute intracranial tuberculosis including miliary tuberculosis, basal meningitis, tuberculomas and neuritis of cranial nerves. All patients had native and contrast enhanced CT and MRI scans. MRI revealed more granulomas and a better imaging contrast in the detection of basal meningitis. Neuritis was diagnosed only with the MRI. MRI scans should be prefered as the imaging procedure in clinically presumed intracranial tuberculosis. (orig.).

92

CT versus MRI in the study of the articular diseases of the knee  

International Nuclear Information System (INIS)

The authors present a comparison between the diagnostic accuracy of Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) in the articular pathologies of the knee. CT and MRI were performed in 30 patients who subsequently underwent surgery. CT and MRI results were compared on three bases: technique, definition of normal anatomy, and diagnostic accuracy. CT allowed a standardization of the technique, while MRI was superior in defining normal anatomy - especially in the study of capsulo-ligamentous structures. In all cases the use of both CT and MRI allowed a correct diagnosis, showing the site, extent and gravity of the lesion. CT proved to be superior to MRI in 4 cases, while MRI corrected CT diagnosis in 11 cases; in 15 patients both techniques had the same diagnostic accuracy. Meniscal tears were better identified by CT, while ...

1988-01-01

93

Usefulness of MRI in diagnosis of hepatocellular carcinoma (HCC)  

Energy Technology Data Exchange (ETDEWEB)

Sixty-six cases of histologically proven hepatocellular carcinomas (HCC) were studied by MRI. Detectability was better by MRI than by CT, especially in the tumor under 2 cm in diameter. The capsule was detected in all cases of HCC over 3 cm in diameter. The capsule was able to be diagnosed only by dynamic MRI study in some cases. High intensity on the T1-weighted image and iso or low intensity on the T2-weighted image suggested that the nodule was adenomatous hyperplasi (AH) or well differentiated HCC. MRI is concluded to be an essential modality in the diagnosis of HCC. (author).

1992-06-01

94

Diagnosis of peanut inhalation by MRI  

International Nuclear Information System (INIS)

We describe a 16-month-old boy presenting with stridor and fever. The chest X-ray suggested inhalation of a foreign body but here was no history of this. A high spot a T_1-weighted chest MRI was due to a peanut which was seen to have moved from the right main bronchus to the left inferior bronchus, between the two MRI studies. MRI can provide information on position and size of the peanut, the conditons of the surrounding tissues and may be also useful in treatment. We consider MRI to be a valuable new method for the diagnosis of peanut inhalation. (orig./GDG).

1992-01-01

95

Birth Weight and Health and Developmental Outcomes in US Children, 1997?2005  

British Library Electronic Table of Contents (United Kingdom)

The primary goal of this study was to assess the association between the full birth weight distribution and prevalence of specific developmental disabilities and related measures of health and special education services utilization in US children. Using data from the 1997?2005 National Health Interview Survey (NHIS) Sample Child Core, we identified 87,578 children 3?17?years of age with parent-reported information on birth weight. We estimated the prevalences of DDs (attention-deficit/hyperactivity disorder [ADHD], autism, cerebral palsy, hearing impairment, learning disability without mental retardation, mental retardation, seizures, stuttering/stammering, and other developmental delay) and several indicators of health services utilization within a range of birth weight categories. We cal...

2011-01-01

96

Facet joint injuries in acute cervical spine trauma : evaluation with CT and MRI  

Energy Technology Data Exchange (ETDEWEB)

To evaluate injury patterns of facet joints and associated soft tissue injuries in patients with acute traumatic cervical facet joint injuries. From among patients with cervical spine trauma, 27 with facet joint injuries, as seen on CT and MRI, were chosen for this study. CT scans were analyzed with regard to the location of facet joint injury, the presence or absence of facet dislocation or fracture, and other associated fractures. MR images were analyzed with regard to ligament injury, intervertebral disc injury, intervertebral disc herniation, and spinal cord injury. The most common location of facet joint injury was C6-7 level(n=10), followed by C5-6(n=8). Among these 27 patients with facet joint injuries, 12(44%) had bilateral injuries and 15(56%) unilateral injuries. Facet fractures were present in 17 cases(63%) and the fracture of inferior facet was more frequent than superior. Patterns of fracture were vertical, transverse, or comminuted, but vertical ...

1999-05-01

97

Ganglioneuromas in childhood: MRI and CT characteristics  

International Nuclear Information System (INIS)

Purpose: The aim of this study was to demonstrate the typical appearance of ganglioneuromas in computer-assisted tomography (CT), and magnetic resonance imaging (MRI). Material and methods: Retrospective analysis of diagnostic imaging (9 CT, 6 MRI) in 9 children aged 3 to 15 years with the histological diagnosis of ganglioneuroma. Results: The tomographies showed large (max. 13.4 cm in diameter) round or oval tumors with sharp delineation. The sites of the tumors were the retroperitoneum (5), the mediastinum (3), and the adrenal gland (1). Intraspinal tumor involvement occurred in 4 cases. On comparing CT with MRI, MRI was more accurate in defining the intraspinal involvement. The ganglioneuromas were of hypodense appearance in the native CT scan and showed moderate enhancement upon administration of contrast media. In five patients tumor calcifications with a disseminated sprinkled pattern were seen in ...

2000-05-01

98

Magnetic resonance imaging (MRI) of the central nervous system in long-term manganese dioxide (MnO{sub 2}) exposed workers; Magnetresonanztomographie des Gehirns bei Beschaeftigten mit chronischer beruflicher Mangandioxid-Exposition  

Energy Technology Data Exchange (ETDEWEB)

Aim: Changes within the brain detected by MRI after chronic manganese poisoning raised the question whether morphological changes of the basal ganglia, particularly of the globus pallidus, could be detected after chronic occupational exposure to manganese dioxide. Results: No cases of parkinsonism were detected in clinical examinations or by other means. The mean manganese concentration in blood was 12 {mu}g/l (range: 3.9-23.3 {mu}g/l). In comparison to the upper reference value of 10 {mu}g/l, 42 workers (56%) had a higher body burden. A significant positive correlation between manganese levels in blood and the PI (indicated by T{sub 1}-shortening) was observed as well as between the CBI and workplace-specific exposure. Brain atrophy was not detected in any of the observed cases. Conclusions: Long-term exposure to manganese dioxide dust correlates with the Pallidum-Index in MRI scans. Although the MRI ...

2000-06-01

99

Uncovering camouflage: amygdala activation predicts long-term memory of induced perceptual insight.  

Science.gov (United States)

What brain mechanisms underlie learning of new knowledge from single events? We studied encoding in long-term memory of a unique type of one-shot experience, induced perceptual insight. While undergoing an fMRI brain scan, participants viewed degraded images of real-world pictures where the underlying objects were hard to recognize ("camouflage"), followed by brief exposures to the original images ("solution"), which led to induced insight ("Aha!"). A week later, the participants' memory was tested; a solution image was classified as "remembered" if detailed perceptual knowledge was elicited from the camouflage image alone. During encoding, subsequently remembered images were associated with higher activity in midlevel visual cortex and medial frontal cortex, but most pronouncedly, in the amygdala, whose activity could be used to predict which solutions will remain in long-term memory. Our findings extend the known roles of amygdala in memory ...

2011-03-10

100

Herlyn-Werner-Wunderlich syndrome: uterus didelphys, blind hemivagina and ipsilateral renal agenesis. Sonographic and MR findings in 11 cases  

Energy Technology Data Exchange (ETDEWEB)

Uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis is a rare entity, sometimes referred to as Herlyn-Werner-Wunderlich syndrome (HWW). It usually presents after menarche with progressive pelvic pain, sometimes with regular menses, and a palpable mass due to hemihaematocolpos. The diagnosis is generally made only if the suspicion of this genitourinary syndrome is raised. To highlight the imaging diagnostic clues in this rare condition. We report on 11 adolescents with this condition. Sonography mostly allowed the correct diagnosis by showing uterovaginal duplication, haematocolpos or haematometrocolpos, and the absence of the ipsilateral kidney. MRI provided more detailed information regarding uterine morphology, the continuity with each vaginal channel (obstructed and nonobstructed), and the bloody nature of the contents. Early and accurate diagnosis of this syndrome is important so that adequate and prompt surgical therapy (excision of the ...

2007-07-15

101

Efficacy of MR mammography (MRM) in providing preoperative locoregional information on breast cancer. Correlation between MRM and histological findings  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to assess the efficacy of MRM in providing preoperative locoregional information on patients with breast cancer. MRI was performed on 62 female breast cancer patients. A 1.5 T MR-system was used to acquire fat-suppressed T{sub 1}WI, T{sub 2}WI and dynamic-contrast-enhanced images with an SPGR pulse sequence. The extent of the cancer measured with MRM was confirmed histologically in all patients. The size obtained from MRM correlated well with the size obtained histologically, including intraductal spread of cancer (R: 0.853). As for shape, the round/oval type evident from MRM correlated more accurately (R: 0.934) than the ill-defined type associated with a linear and/or clumped enhanced area (R:0.744). The difference between the size obtained from MRM and the size obtained histologically, including IDS, was less than 15 mm in the majority of patients (93.5%). MRM accurately reveals the extent of cancer, including IDS, and is effective ...

2002-07-01

102

Application of a beta microprobe for quantification of regional cerebral blood flow with {sup 15}O-water and PET in rhesus monkeys  

Energy Technology Data Exchange (ETDEWEB)

A beta microprobe was successfully applied to monitor arterial input function for quantification of regional cerebral blood flow (rCBF) in the monkey brain with {sup 15}O-water and positron emission tomography (PET). The sensitivity of the probe was approximately 0.83 to 1.67 cps/kBq/ml depending on the studies. A preliminary study was performed to find a suitable use and to evaluate the performance of the system and data analysis procedure. The results showed that dispersion correction of measured input function was unnecessary if microprobes were connected directly to the arterial catheter. Then multiple CBF measurements were done in three monkeys under anesthesia. Identical regions of interest were placed with the aid of magnetic resonance imaging (MRI) of each monkey and rCBF values were estimated. Estimated rCBFs were reproducible for several measurements. The mean CBF value for a pentobarbital anesthetized monkey was 46.0 ml/min/100 g ...

1998-02-01

103

Fetal magnetic resonance imaging of the brain: technical considerations and normal brain development  

International Nuclear Information System (INIS)

Fetal MRI examines non-invasively the unborn fetus. Ultrafast MRI sequences effectively suppress fetal motion. Multiple case reports and studies have shown that fetal MRI is particularly helpful in the evaluation of the central nervous system. The high contrast-to-noise ratio, the high spatial resolution, the multiplanar capabilities, the large field of view and the simultaneous visualisation of fetal and maternal structures have proven to be advantageous. Fetal MRI is particularly helpful in the evaluation of the normal and pathological development of the brain. Despite the fact that no side effects have been reported or are to be expected, the use of MRI during pregnancy is still limited to the second and third trimester of pregnancy. Magnetic resonance imaging contrast media are not to be used as it passes the placenta. Ultrasound remains the primary screening modality for fetal ...

2002-08-01

104

Self-consistent augmented-plane-wave electronic-structure calculations for the A15 compounds V_3X and Nb_3X, X = Al, Ga, Si, Ge, and Sn  

International Nuclear Information System (INIS)

We have performed self-consistent (SC) band structure calculations for the A15 compounds V_3X and Nb_3X, X = Al, Ga, Si, Ge, and Sn, using the augmented-plane-wave (APW) method. Relativistic effects (except the spin-orbit interaction) have been included in each SC cycle, along with corrections to the usual muffin-tin approximation. The latter apply the APW wave functions outside of the muffin-tin spheres to compute the interstitial charge densities and potentials. The resulting interstitial potential has full cubic symmetry (no spherical averaging), although a spherically averaged muffin-tin form is retained inside the spheres. The final SC potentials were used to generate energies and wave functions on a cubic mesh of 35 k points in 1/48th of the Brillouin zone. These results were interpolated onto a finer mesh of 969 k points using a symmetrized Fourier method; the densities of states (DOS), N (E), were determined using tetrahedral integration. These accurate interpolation methods ...

105

Differential diagnosis of rheumatic diseases; Differenzialdiagnose rheumatischer Erkrankungen  

Energy Technology Data Exchange (ETDEWEB)

Which imaging modalities are appropriate for the Differential diagnosis of Rheumatic diseases. MRI has far most the highest sensitivity and is unequaled in its brilliant presentation of Anatomy and Pathology. But it is sometimes forgotten, that this is at least in part the result of carefully selected sequences, dedicated to the expected result. In a method totally independent of any result, this should not be the case. In contrary this method should be highly standardised and regardless what will be the findings. This is true for Plain X-ray. It will be shown, that already the outer silhouette of the soft parts with different features of swelling, and differences in density and even more - defects or appositions of the bony silhouette in the majority of cases at least will allow to classify the patient for a group of diseases and in many cases will lead to a definite diagnosis. Differential diagnoses like Rheumatoid Arthritis versus Psoriatic ...

2006-05-15

106

Visualization of the salivary glands. CT and MRI  

International Nuclear Information System (INIS)

For the evaluation of diseases of salivary origin, ultrasound and/or sialography is recommended instead of MRI. In cases of salivary tumor, ultrasound may be helpful in delineating superficial tumors. For small tumors no further imaging is needed. When dealing with a large tumor or a tumor in the deep lobe of the parotid gland, MRI is the preferred imaging method. Not only does MRI provide a large variety of soft tissue signal differences, but also the multiplanar facilities are helpful in delineating the extent of the tumor, whether located in the submandibular, sublingual, or parotid gland. Skull base invasion is often well seen by MRI. Subtle changes may be missed and in those cases CT is recommended to exclude or prove destruction of the skull base. For the evaluation of patients presenting with a recurrent pleomorphic adenoma, MRI is recommended in all patients. ...

107

Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as an MRI contrast agent  

UK PubMed Central (United Kingdom)

The purpose of this study was to synthesize biocompatible polyvinylpyrrolidone (PVP)-coated iron oxide (PVP-IO) nanoparticles and to evaluate their efficacy as a magnetic resonance imaging (MRI)...Full Text Available

2008-04-01

108

Numerical field calculations considering the human subject for engineering and safety assurance in MRI  

UK PubMed Central (United Kingdom)

Numerical calculations of static, switched, and radiofrequency (RF) electromagnetic (EM) fields considering the geometry and EM properties of the human body are used increasingly in MRI to explain...Full Text Available

2009-11-01

109

MRI features of epidural extramedullary hematopoiesis  

Energy Technology Data Exchange (ETDEWEB)

A case of {beta}-thalassemia intermedia with spinal cord compression due to extramedullary hematopoiesis, which was successfully treated by blood transfusion, is presented. Emphasis was made on the MRI appearance of extramedullary hematopoiesis on different pulse sequences. The theories that aimed to explain the involvement of the epidural space by extramedullary hematopoiesis are discussed.

2000-07-01

110

Early detection of bone metastases of Ewing's sarcoma by magnetic resonance imaging  

International Nuclear Information System (INIS)

Bone metastases of an Ewing's sarcoma were detected by magnetic resonance imaging (MRI), when bone scan, CT and plain films were still normal. This is due to the ability of MRI to detect intramedullary metastases before involvement of the cortex. (Auth.).

111

EXPONENTIAL TENSORS: A FRAMEWORK FOR EFFICIENT HIGHER-ORDER DT-MRI COMPUTATIONS  

UK PubMed Central (United Kingdom)

In Diffusion Tensor Magnetic Resonance Image (DT-MRI) processing a 2nd order tensor has been commonly used to approximate the diffusivity function at each lattice...Full Text Available

2007-05-15

112

Analysis of the Development of the Nasal Septum according to Age and Gender Using MRI  

UK PubMed Central (United Kingdom)

ObjectivesThis study was designed to evaluate the normal development of the nasal septum in Koreans using sagittal MRI for the valuable clinical information on septal procedures.MethodsTwo...Full Text Available

2008-03-01

113

Adaptive Thresholding for Improving Sensitivity in Single-Trial Simultaneous EEG/fMRI  

UK PubMed Central (United Kingdom)

A common approach used to fuse simultaneously recorded EEG and fMRI is to correlate trial-by-trial variability in the EEG, or variability of components derived therefrom, with the blood oxygenation...Full Text Available

114

Clinical magnetic resonance imaging with nuclear medicine correlation  

Energy Technology Data Exchange (ETDEWEB)

The current role of magnetic resonance imaging (MRI) in different organ systems is discussed and compared to nuclear medicine and to other available clinical diagnostic modalities. The value of optimizing radiofrequency pulse sequence selection to provide additional tissue characterization is also described. The results of nuclear medicine and MRI studies in 56 patients are compared to evaluate the clinical diagnostic contribution of each imaging modality for various pathological processes. In addition, the state-of-the-art MRI systems and future development in MRI technology with its potential contribution is defined.

1985-08-01

115

Practical MRI atlas of neonatal brain development  

International Nuclear Information System (INIS)

This book is an anatomical reference for cranial magnetic resonance imaging (MRI) studies in neonates and infants. It contains 122 clear, sharp MRI scans and drawings showing changes in the normal appearance of the brain and skull during development. Sections of the atlas depict the major processes of maturation: brain myelination, development of the corpus callosum, development of the cranial bone marrow, and iron deposition in the brain. High-quality scans illustrate how these changes appear on magnetic resonance images during various stages of development.

116

Comparative Study of SVM Methods Combined with Voxel Selection for Object Category Classification on fMRI Data  

UK PubMed Central (United Kingdom)

BackgroundSupport vector machine (SVM) has been widely used as accurate and reliable method to decipher brain patterns from functional MRI (fMRI) data. Previous studies have not...Full Text Available

117

The ZNF804A gene: characterization of a novel neural risk mechanism for the major psychoses.  

Science.gov (United States)

Schizophrenia and bipolar disorder share genetic risk, brain vulnerability, and clinical symptoms. The ZNF804A risk variant, rs1344706, confers susceptibility for both disorders. This study aimed to identify neural mechanisms common to both schizophrenia and bipolar disorder through this variant's potential effects on cortical thickness, white matter tract integrity, and cognitive function. Imaging, genetics, and cognitive measures were ascertained in 62 healthy adults aged between 18 and 59 years. High-resolution multimodal MRI/DTI imaging was used to measure cortical thickness and major frontotemporal and interhemispheric white matter tracts. The general linear model was used to examine the influence of the ZNF804A rs1344706 risk variant on cortical thickness, white matter tract integrity, and cognitive measures. Individuals homozygous for the risk variant ('A' allele) demonstrated reduced cortical gray matter thickness in the superior temporal gyrus, and in the ...

2011-04-27

118

Rational imaging strategies in larynx disease; Rationelle bildgebende Strategien bei Kehlkopferkrankungen  

Energy Technology Data Exchange (ETDEWEB)

Clinical information is indispensable for swift and cost-effective clarification of diseases of the larynx. While quality clarification of neurological changes in the area of the posterior cranial fossa and in the course of the vagus nerve as a cause of glottis malfunction is possible with MRI, localized disease of the larynx can more effectively be assessed with low-artifact CT. In the particularly difficult assessment of the post-operative larynx, a recurrence can be diagnosed only after a baseline study has been carried out after the end of therapy. With knowledge of the pretherapeutic findings, the findings immediately post-therapy, and the operation technique used, the optimal CT examination, which can be carried out quickly, will be able to provide more information about recurrence. (orig.) [Deutsch] Zur schnellen und kostenguenstigen Abklaerung von Erkrankungen des Larynx ist die klinische Information unabdingbar: ...

1998-02-01

119

Hyperoxia-induced acute lung injury using a pig model. Correlation between MR imaging and histologic results  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to correlate MR imaging findings with pathology in experimental hyperoxia-induced acute lung injury, which has similar pathology to diffuse alveolar damage (DAD). Seventeen Yorkshire pigs were studied. These animals were exposed to more than 80% oxygen for 24, 48, 72, and 96 hours in a sealed cage. The lungs were removed and inflated with air infused through the trachea, and then examined by both MRI and high-resolution CT (HRCT). T1-weighted spin-echo (T1WSE), T2-weighted fast (T2WFSE), and half-Fourier acquisition single-shot turbo spin-echo (HASTE) sequences were performed. Severity in MR findings and signal-to-noise ratios (SNR) on MR images were well correlated with pathological scores. CT values were also correlated well with pathologic scores. Abnormal SNR values were obtained from a pathological score of 5, whereas abnormal CT values were obtained from a pathological score of 15. ...

2001-06-01

120

PET/MRI hybrid imaging: devices and initial results  

British Library Electronic Table of Contents (United Kingdom)

The combination of functional and morphological imaging technologies such as positron emission tomography (PET) and X-ray computed tomography (CT) has shown its value in the clinical and preclinical field. However, CT provides only very limited soft-tissue contrast and exposes the examined patient or laboratory animal to a high X-ray radiation dose. In comparison to CT, magnetic resonance tomography (MRI) provides excellent soft-tissue contrast and allows for nuclear magnetic resonance spectroscopy (NMRS) or functional MRI (fMRI). Thus, the combination of PET and MRI has been pursued for several years. First approaches have succeeded using conventional photo multiplier tube (PMT) technology together with light fibers to transfer scintillation light away from the high magnetic field. Latest...

2008-01-01

121

PET and MRI in cardiac imaging: from validation studies to integrated applications  

International Nuclear Information System (INIS)

Positron emission tomography (PET) is the gold standard for non-invasive assessment of myocardial viability and allows accurate detection of coronary artery disease by assessment of myocardial perfusion. Magnetic resonance imaging (MRI) provides high resolution anatomical images that allow accurate evaluation of ventricular structure and function together with detection of myocardial infarction. Potential hybrid PET/MR tomography may potentially facilitate the combination of information from these imaging modalities in cardiology. Furthermore, the combination of anatomical MRI images with the high sensitivity of PET for detecting molecular targets may extent the application of these modalities to the characterization of atherosclerotic plaques and to the evaluation of angiogenetic or stem cell therapies, for example. This article reviews studies using MRI and PET in parallel to compare their performance in cardiac ...

2009-03-01

122

New procedures. Comprehensive staging of lung cancer by MRI  

International Nuclear Information System (INIS)

Lung cancer staging according to the TNM system is based on morphological assessment of the primary cancer, lymph nodes and metastases. All aspects of this important oncological classification are measurable with MRI. Pulmonary nodules can be detected at the clinically relevant size of 4-5 mm in diameter. The extent of mediastinal, hilar and supraclavicular lymph node affection can be assessed at the same time. The predominant metastatic spread to the adrenal glands and spine can be detected in coronal orientation during dedicated MRI of the lungs. Search focused whole body MRI completes the staging. Various additional MR imaging techniques provide further functional and clinically relevant information during a single examination. In the oncological context the most important techniques are imaging of perfusion and tumor motion. Functional MRI of the lungs complements the pure staging and improves ...

2010-08-01

123

Magnetic resonance imaging of chronic aortic dissection  

International Nuclear Information System (INIS)

17 patients with chronic aortic dissection were examined by MRI. In 12 patients, comparison between gradient echo sequences and SE sequences was possible. Gradient echo sequences, unlike SE sequences, permitted evaluation of flow in the true and false lumen, reliable differentiation between thrombus and flowing blood and clear delination of the intimal flap. An additional comparison between transoesophageal ultrasound and MRT in 15 patients showed significant advantages in favour of MRI. In three patients MRI was able to detect more proximal origins of the dissection. Moreover, MRI allowed evaluation of the major aortic branches and their relation to the dissection; this was not possible with ultrasound. MRI plays an important role in the follow-up of chronic aortic dissections. (orig.).

124

MRT for operation planning in anal atresias  

International Nuclear Information System (INIS)

We evaluated in this study the value of preoperative examinations of anal atresia with an optimised MRI strategie. 13 patients with anorectal anomalies, most of them younger than one year, underwent an MRI examination of the pelvis. 10 of these patients were operated afterwards. Compared with the situs shown by the operation the results of the MRI examination were very exact in all cases in respect of the level of atresia and the development of the striateed muscle complex. Fistulas could be completely described in most cases. MRI demonstrated additional lesions in some patients which were of great importance for planning the further treatment of the patients. As a consequence MRI can give valid information on anal atresia for planning the operative treatment. (orig.).

125

Lacrimal gland masses on CT and MRI: a report of four cases  

International Nuclear Information System (INIS)

In an extended case report, we discuss four cases with masses in the lacrimal fossa representing the most important entities in this region (lymphoma, pleomorphadenoma, inflammatory pseudotumor, and malignant epithelial tumor). The different indications for CT and MRI are explained. For the differential diagnosis of lacrimal gland lesions, the following imaging parameters are important: The shape of the lacrimal gland, the inner structure, the degree of contrast enhancement, and the surrounding bony structures. In the evaluation of the expansion of lacrimal gland lesions, CT in thin slices with multiplanar reconstructions is equal to MRI. However, the contrast-enhancement of lacrimal glands is better evaluated with MRI than with CT. The bony structures are better visualized on CT than on MRI. (orig.).

126

Dissection of the thoracic aorta - role of CT and MRT following aortic replacement  

International Nuclear Information System (INIS)

Dynamic CT and MRT were performed in 21 patients who had undergone prosthetic replacement of the aorta because of dissection of the thoracic aorta. There is no difference between MRI and dynamic CT in the demonstration of a persistent intimal flap, the formation of a thrombus and the assessment of the aortic diameter in patients who underwent surgery for thoraco-abdominal aortic dissection. MRI, however, is superior in the identification of the true and false lumen and the demonstration of the distal anastomotic site. The major advantages of MRI are that there is no need for intravenous contrast agents, that it is high sensitive to flow phenomena, and that it can demonstrate the aortic arch and the ascending aorta on sagittal oblique sections. The major disadvantages of MRI are the limited access to the patient during the procedure, and the inability to examine patients fitted with pacemakers or who are ...

127

PET/MRI hybrid imaging: devices and initial results  

International Nuclear Information System (INIS)

The combination of functional and morphological imaging technologies such as positron emission tomography (PET) and X-ray computed tomography (CT) has shown its value in the clinical and preclinical field. However, CT provides only very limited soft-tissue contrast and exposes the examined patient or laboratory animal to a high X-ray radiation dose. In comparison to CT, magnetic resonance tomography (MRI) provides excellent soft-tissue contrast and allows for nuclear magnetic resonance spectroscopy (NMRS) or functional MRI (fMRI). Thus, the combination of PET and MRI has been pursued for several years. First approaches have succeeded using conventional photo multiplier tube (PMT) technology together with light fibers to transfer scintillation light away from the high magnetic field. Latest PET/MRI developments use solid-state light detectors that can be operated even at high ...

2008-06-01

128

MRI of congenital heart disease in childhood  

International Nuclear Information System (INIS)

MRI provides a non-invasive diagnostic tool complementing echocardiography on one hand, and showing advantages over echocardiography, on the other hand, especially after corrective procedures. The multiple different MRI sequences need to be adapted to examinations of children and patients with congenital heart disease (CHD), and can be used to detect morphologic changes, blood-flow in the heart and thoracic vessels and diastolic or systolic function of myocardium. Several factors determine the success of the examination of a complex congenital heart disease or a postoperative situs. Pediatric radiologists and radiologists experienced in congenital heart diseases have to work in close cooperation. Echocardiography should be performed before MRI. The results of prior examinations and the clinical history of the patients, including possible palliative or reconstructive operations, must be available before ...

2004-02-01

129

MRI in definition of bleeding source, lesion pattern and therapy in haemarthros of the knee  

International Nuclear Information System (INIS)

Patients with haemarthros of the knee were examined by MRI and arthroscopy to identify the bleeding source and to determine surgical or conservative therapy. A prospective study was performed on 120 patients who underwent MRI and arthroscopy, point lesions and bleeding sources were documented separately on a standardised form. Arthroscopy demonstrated a ruptured anterior cruciate ligament in 86%, meniscal tears in 55%, disruption of collateral ligaments in 17%, osteochondral lesions in 5% and tears of capsule or plicae in 13%. Disruption of cruciate ligaments caused haemorrhage in all but three cases. In contrast, only meniscal tears located very adjacent to the meniscal basement had bled. Those types of osteochondral lesions caused haemorrhage characterised on MRI by destruction of the subchondral plate and overlying cartilage. Severe lesions of the knee were diagnosed by MRI in 71% to 100%, slight ...

130

Incidence of lesions as described by MRI in focal epilepsy of frontal and temporal onset; Inzidenz kernspintomographisch erfassbarer Laesionen bei der Abklaerung fokaler Epilepsien frontalen und temporalen Ursprunges  

Energy Technology Data Exchange (ETDEWEB)

Aim: Today, MRI is an integral part of the presurgical evaluation of patients suffering from partial epilepsy. These patients frequently show focal morphological abnormalities with potential epileptogenic character and surgical resection of these lesions is associated with superior postsurgical outcome as to seizure frequency. Apart from easily detectable defects, such as post-traumatic lesions or cerebral infarction, as wide variety of mainly small abnormalities can be detected using MRI. Methods: In this study, 484 patients suffering from partial epilepsy of temporal or frontal onset were evaluated for the incidence of different lesions in this population. Results: All lesions found were included without evaluating their potential epileptogenicity, which remains to be proven using other procedures (EEG, SPECT, PET, etc.). Involvement of the hippocampal formation was a major finding in temporal lobe epilepsy, which could ...

1997-09-01

131

The diagnostic value of MRI and gadolinium-DTPA compared with CT for the diagnosis of bladder tumours  

International Nuclear Information System (INIS)

In a prospective study, 58 patients with carcinomas of the bladder were examined by CT and MRI; in 48, gadolinium-DTPA was administered intravenously. MRI provided exact staging in 89%, compared with 80% with CT. There was 13% over-staging with CT and 11% with MRI. MRI, unlike CT did not result in any under-staging. In 36 patients a quotient could be calculated from the signal intensity of the tumour and surrounding soft tissues both before and after the intravenous contrast medium and the increased quotient after contrast administration could be estimated. There was a significant increase in the tumour/muscle quotient with a mean of 72#+-#22% (minimum 43%, maximum 153%), corresponding to a marked increase of the signal form the tumour when compared with the precontrast images. This had the following advantages compared with CT: Accurate differentiation between superficial and intramural spread. ...

132

Modern imaging methods for diagnostic evaluation of tumors of the oropharynx and the oral cavity  

International Nuclear Information System (INIS)

Differentiating a benign from a malignant lesion by information such as density data, or signal intensities or echo gradients, is not possible with CT, nor MRI, nor ultrasonography. Only some lesions show characteristic signs. Inflammations cannot be difscriminated from malignant tumors. CTs of small tumors in particular are so poor in contrast that it is much more difficult to detect tumors or discriminate them from other lesions, as compared to MR images or ultrasonographs. CT does not detect surface tumors, but is more sensitive than MRI or US in detecting discrete cortical bone lesions. The same applies to small calcified tumors. MRI however is most sensitive in detecting tumor volumes in the yellow marrow, and is the best modality for evaluation of extraossal extension of tumors. CT yields better results than MRI if applied for simultaneous screening of lymph node metastases in the lower neck. ...

133

Determination of left ventricular ejection fraction and wall thickness in magnetic resonance imaging at 1.0 Tesla in comparison to echocardiography and biplanar ventriculography  

International Nuclear Information System (INIS)

We compared the values of the myocardial thickness and the left ventricle diameters measured with MRI and echocardiography. The ejection fraction was compared in MRI and ventriculography. 34 patients with different heart dysfunctions were examined with MRI (FISP 2D sequence). 26 of them were also studied by echocardiography and 20 by biplane cine-ventriculography. The enddiastolic thicknesses of the left ventricular postero-lateral wall and of the septum interventriculare were measured on short axis images. An ellipsoidal modell was used for volume calculation and ejection fraction. Correlation of MRI values of thickness and ejection fraction with echocardiographi and angiographi showed r>0,8. As known for 1.56 T Imagers, the myocardial thickness in MRI was underestimated compared to echocardiography (1.4 mm#+-#1.7). The ejection fraction was underevaluated compared to ...

134

Synovial cysts of the lumbar spine: CT and MRI correlations  

Energy Technology Data Exchange (ETDEWEB)

Intraspinal synovial cysts were diagnosed in six patients during a 5-year period and retrospectively studied. Plain films of the lumbar spine showed degenerative changes in all patients. Lumbar myelography showed a posterior and lateral defect caused by extradural compression. Using CT without contrast enhancement established the diagnosis in five of the six patients. In four cases MRI was performed, three before and after injection of gadolinium diethyline-triamine penta-acetic acid (Gd-DTPA). Including the patient with a false-negative CT, MRI was positive in all patients. (orig.)

1994-08-01

135

Nasal cavity volume measured in normal persons by MRI  

Energy Technology Data Exchange (ETDEWEB)

Nasal cavity volume was studied in 69 healthy volunteers (from 8 to 23 years old) by MRI. The right and left nasal cavity areas were measured on horizontal images displayed directly on the MRI console. The nasal cavity volume was obtained by integrated volume calculation. The nasal cavity volume was positively correlated with age, body height and weight up to age 16. The body height and weight reached a plateau at 16 years, but the nasal cavity volume continued to increase. There was no significant difference in the volumes of the right and left cavities. (author).

1993-10-01

136

Nasal cavity volume measured in normal persons by MRI  

International Nuclear Information System (INIS)

Nasal cavity volume was studied in 69 healthy volunteers (from 8 to 23 years old) by MRI. The right and left nasal cavity areas were measured on horizontal images displayed directly on the MRI console. The nasal cavity volume was obtained by integrated volume calculation. The nasal cavity volume was positively correlated with age, body height and weight up to age 16. The body height and weight reached a plateau at 16 years, but the nasal cavity volume continued to increase. There was no significant difference in the volumes of the right and left cavities. (author).

137

Diffusion-weighted MRI suggests the coexistence of cytotoxic and vasogenic oedema in a case of deep cerebral venous thrombosis  

Energy Technology Data Exchange (ETDEWEB)

We report a 20-year-old woman who suffered headaches before presenting with a state of fluctuating vigilance. MRI showed diffuse high signal in the basal ganglia bilaterally on diffusion- and T2-weighted images, which had areas of both low and high apparent diffusion coefficient, presumed to correspond to cytotoxic and vasogenic oedema. MR venography showed no flow in the deep cerebral veins or straight sinus. Heparin was given, with clinical recovery. On follow-up MRI, the appearances became normal. (orig.)

2000-10-01

138
139

Spatiotemporal Evolution of the fMRI Response to Ultrashort Stimuli  

UK PubMed Central (United Kingdom)

The specificity of the hemodynamic response function (HRF) is determined spatially by the vascular architecture and temporally by the evolution of hemodynamic changes. The stimulus duration...Full Text Available

2011-01-26

140

Multimodal MRI assessment of damage and plasticity caused by status epilepticus in the rat brain  

British Library Electronic Table of Contents (United Kingdom)

Summary Status epilepticus or other brain-damaging insults launch a cascade of events that may lead to the development of epilepsy. MRI techniques available today, including T2- and T1-weighted imaging, functional MRI, manganese enhanced MRI (MEMRI), arterial spin labeling (ASL), diffusion tensor imaging (DTI), and phase imaging, can detect not only damage caused by status epilepticus but also plastic changes in the brain that occur in response to damage. Optimal balance between damage and recovery processes is a key for planning possible treatments, and noninvasive imaging has the potential to greatly facilitate this process and to make personalized treatment plans possible.

2011-01-01

141

Large (≥2cm) non-hypervascular nodules depicted on MRI in the cirrhotic liver: fate and implications  

British Library Electronic Table of Contents (United Kingdom)

Aim To determine the fate and clinical implication of large (?2cm), non-hypervascular nodules depicted on magnetic resonance imaging (MRI) in the cirrhotic liver. Materials and methods In 21 patients with cirrhosis (14 hepatitis B, two ethanol abuse, four cryptogenic, one Wilson's disease), 25 large (?2cm in the longest dimension) non-hypervascular nodules were identified on dynamic MRI. The implications for diagnosis of the initial size, contour, and signal characteristics on MRI in addition to patients' age and cause of cirrhosis were assessed in our analysis. Results Twelve (75%) out of 16 lesions were malignant or potentially-malignant from 14 hepatitis B patients, while seven (78%) of the nine lesions from other patients were benign (p=0.016). The mean age of the patients who ha...

2008-01-01

142

In vivo MRI analysis of an inflammatory injury in the developing brain  

UK PubMed Central (United Kingdom)

Cerebral periventricular white matter injury stands as a leading cause of cognitive, behavioral and motor impairment in preterm infants. There is epidemiological and histopathological evidence...Full Text Available

2010-07-01

143

Identification and staging of bladder carcinoma  

International Nuclear Information System (INIS)

The purpose of the present study was to compare the effectiveness of MRI, CT and radioimmunoscintigraphy in the staging and detection of bladder cancers in 28 patients. We distinguish two groups: Group I included the tumour stages CIS-T_3_A and the second group the deep infiltrative tumours T_3_B-T_4. MRI was slightly superior to CT in respect of tumour staging (75% correct results as compared to 63%). No understaging occurred with MRI, whereas in 22% of the cases the stage of the tumour was underestimated using CT diagnostics. Overstaging occurred in 25% of the MRI and 15% of the CT-diagnostics, respectively. RIS cannot distinguish the tumour groups, and hence this method is useful only for the detection of the primary tumour and metastases. In 77% of cases the tumour was detected and in 15% the tumour could be safely excluded. (orig.).

144

Functional MRI-compatible laparoscopic surgery training simulator  

British Library Electronic Table of Contents (United Kingdom)

Abstract During the past few years, laparoscopy has become the gold standard for some surgical procedures and its applications continue to expand. Because of multiple factors such as loss of tactile perception, two-dimensional visualization of the three-dimensional surgical field, and demanding bimanual hand-eye coordination, special training is required to achieve proficiency with laparoscopy. In this study, as the first step toward evidence-based development of strategies to improve the quality of laparoscopy training from brain activity and behavior relationships, a laparoscopy training simulator was developed for use in functional MRI. Experiments confirmed the functional MRI compatibility of the device. Representative behavioral and functional MRI results for two subjects showed the f...

2011-01-01

145

Final Report of OT-45, PVM-8, and RVTO Weather ...  

Science.gov (United States)

... A second hydrometeor sampler (MRI Model 1220 ... The cloud particle probe normally installed in ... to the northeast showed no significant movement. ...

1975-07-01

146

PET and MR imaging in a neuro-Behcet syndrome  

Energy Technology Data Exchange (ETDEWEB)

Positron emission tomography (PET) and magnetic resonance imaging (MRI) studies were performed on a case of neuro-Behcet's syndrome. In accordance with the clinical signs, FDG PET (using /sup 18/F-labeled 2-F-2'-desoxyglucose) revealed disseminated storage defects in the cerebrum and cerebellum. Focal regions of enhanced signal intensity were demonstrated in the parietal white matter of the cerebrum in T2-weighted images and in the brain stem by MRI. (orig.).

1989-11-01

147

Metastatic Ewing's sarcoma to the skull: CNS involvement excluded by MRI  

International Nuclear Information System (INIS)

A case of metastatic Ewing's sarcoma to the skull is presented, demonstrating the superiority of magnetic resonance imaging over other imaging modalities to exclude CNS involvement. Precise delineation of different tumor components in extradural location contained in an intact dural rim together with compressed cortex showing no signs of tumorous involvement constituted an MRI appearance allowing us to exclude tumor outgrowth into the brain. (orig.).

148

MRI and 1H MRS of The Breast: Presence of a Choline Peak as Malignancy Marker is Related to k21 Value of the Tumor in Patients with Invasive Ductal Carcinoma  

UK PubMed Central (United Kingdom)

To assess which specific morphologic features, enhancement patterns, or pharmacokinetic parameters on breast Magnetic Resonance Imaging (MRI) could predict a false-negative outcome of Proton...Full Text Available

2008-01-01

149

Implant detectibility of intervertebral disc spacers in post fusion MRI: evaluation of the MRI scan quality by using a scoring system - an in vitro study  

International Nuclear Information System (INIS)

Intervertebral spacers for anterior spine fusion are made of different materials, such as titanium and cobalt chromium alloys and carbon fiber-reinforced polymers. Implant-related susceptibility artifacts can decrease the quality of MRI scans. The aim of this cadaveric study was to demonstrate the extent that implant-related MRI artifacting affects the postfusion differentiation of determined regions of interest (ROIs). In six cadaveric porcine spines, we evaluated the postimplantation MRI scans of a titanium, cobalt-chromium and carbon spacer that differed in shape and surface qualities. A spacer made of human cortical bone was used as a control. A defined evaluation unit was divided into ROIs to characterize the spinal canal as well as the intervertebral disc space. Considering 15 different MRI sequences read independently by an interobserver-validated team of specialists the artifact-affected image ...

2007-02-01

150

MRI in pleural diseases  

International Nuclear Information System (INIS)

The MRI and CT appearances in 48 patients with histologically confirmed benign and malignant pleural abnormalities were compared retrospectively. Abnormal pleural changes were shown in 47 out of the 48 patients by high signal intensity of the pleura in T_2-weighted sequences and in contrast enhanced T_1-weighted sequences on MRI. CT showed abnormalities in 45 out of 48 patients. Delineation of pleural and pulmonary changes by CT was possible in 13 out of 23 cases, and pleural disease from effusions in 15 out of 28 cases. T_2-weighted MRI was successful in 14 out of 23 and 4 out of 28 cases, respectively. T_1-weighted images after contrast were successful in 20 out of 23 and 22 out of 28 cases, respectively. Indications of malignant pleural disease were the presence of mediastinal or circumferential involvement or involvement of the entire pleura, thickness of more than 10 mm and nodular changes. The most reliable sign of ...

151

Functional MRI of the visual cortex and visual testing in patients with previous optic neuritis.  

DEFF Research Database (Denmark)

The volume of cortical activation as detected by functional magnetic resonance imaging (fMRI) in the visual cortex has previously been shown to be reduced following optic neuritis (ON). In order to understand the cause of this change, we studied the cortical activation, both the size of the activated area and the signal change following ON, and compared the results with results of neuroophthalmological testing. We studied nine patients with previous acute ON and 10 healthy persons served as controls using fMRI with visual stimulation. In addition to a reduced activated volume, patients showed a reduced blood oxygenation level dependent (BOLD) signal increase and a greater asymmetry in the visual cortex, compared with controls. The volume of visual cortical activation was significantly correlated to the result of the contrast sensitivity test. The BOLD signal increase correlated significantly to both the results of the contrast sensitivity test ...

2002-01-01

152

Comparison of high resolution whole-body MRI using parallel imaging and PET-CT. First experiences with a 32-channel MRI system  

International Nuclear Information System (INIS)

To compare the accuracy in the detection and staging of various malignant tumors with high resolution whole-body MRI using parallel imaging with whole-body dual-modality PET-CT. Preliminary results of an interim analysis from a prospective, blinded study are presented, in which 20 patients (mean age 59 years, range 27-77 years) with different oncological diseases underwent whole-body dual modality FDG-PET-CT screening for tumor search or staging in case of confirmed or suspected metastatic disease. All patients also underwent whole-body MRI imaging with the use of parallel imaging (iPAT). High-resolution coronal T1w- and STIR-sequences of 5 body levels with 512 x 512 matrix, axial fast T2w imaging of lung and abdomen (HASTE), contrast-enhanced dynamic and static T1w-sequences of liver, brain, abdomen, and pelvis were performed. Using a 32-channel whole-body MRI scanner (Magnetom Avanto, Siemens Medical Solutions) with a ...

153

Vessel wall MRI of the thoracic aorta: correlation to histology and transesophageal ultrasound. Preliminary results  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To visualise the vessel wall of the descending thoracic aorta using magnetic resonance imaging. To evaluate the diagnostic potential of tailored T{sub 1}-weighted sequences with contrast enhancement to assess systemic atherosclerotic disease. Methods: This study was performed on a clinical 1.5 Tesla scanner using a gradient strength of 30 mT/m and the phased array spine coil. A cadaver was examined to optimise a magnetic resonance imaging (MRI) protocol to evaluate atherosclerotic aortic wall disease. The acquired MR images were compared to gross specimens and histology. Subsequently seven patients who had undergone transesophageal ultrasound (TEU) with detailed assessment of the descending thoracic aorta were examined with MRI. The optimised protocol included untriggered and fat suppressed T{sub 2}-weighted turbo spin echo sequences and ECG-triggered and fat suppressed T{sub 1}-weighted spin echo sequences before and after iv ...

2002-05-01

154

Yost finds yet another reason to be paranoid  

CERN Document Server

Yost finds yet another reason to be paranoid

2008-01-01

155

Influence of contrast-enhanced CT and MRI with or without SPIO particles on therapy and therapy costs for patients with focal liver disease  

International Nuclear Information System (INIS)

Purpose: Evaluation of the diagnostic efficacy and cost-benefit of contrast enhanced CT (CT) and MRI pre- and post-SPIO-particles in focal hepatic disease with consideration of therapeutic outcome. Results: In 34/52 (65.4%) of the cases the correct diagnosis was primarily stated by CT (sensitivity [se.] 85.2%, specificity [sp.] 44.0%). In additional 10/52 of the cases unenhanced MRI (se. 91.4%, sp. 75.0%) enabled correct diagnoses, and in another 6 cases the diagnosis was established only by SPIO-MRI (se. 100%, sp. 86.7%). Considering the possible therapeutic recommendation arising from each modality, CT would have induced needless therapy costs of 191,042 DM, unenhanced MRI of 171,035 DM, and SPIO-MRI of 7,311 DM. In comparison to the real therapy costs of 221,873 DM, this would have corresponded to an unnecessary increase of therapy costs of 86.1%, 77.1%, and 3.3%, respectively. ...

2000-03-01

156

Development of a geometrically accurate imaging protocol at 3 Tesla MRI for stereotactic radiosurgery treatment planning  

International Nuclear Information System (INIS)

The purpose of this study is to develop a geometrically accurate imaging protocol at 3 T magnetic resonance imaging (MRI) for stereotactic radiosurgery (SRS) treatment planning. In order to achieve this purpose, a methodology is developed to investigate the geometric accuracy and stability of 3 T MRI for SRS in phantom and patient evaluations. Forty patients were enrolled on a prospective clinical trial. After frame placement prior to SRS, each patient underwent 3 T MRI after 1.5 T MRI and CT. MR imaging protocols included a T1-weighted gradient echo sequence and a T2-weighted spin echo sequence. Phantom imaging was performed on 3 T prior to patient imaging using the same set-up and imaging protocols. Geometric accuracy in patients and phantoms yielded comparable results for external fiducial reference deviations and internal landmarks between 3 T and 1.5 T MRI (mean ?0.6 mm; ...

2010-11-21

157

In vitro MRI of brain development  

International Nuclear Information System (INIS)

In this review, we demonstrate the developmental appearance, structural features, and reorganization of transient cerebral zones and structures in the human fetal brain using a correlative histological and MRI analysis. The analysis of postmortem aldehyde-fixed specimens (age range: 10 postovulatory weeks to term) revealed that, at 10 postovulatory weeks, the cerebral wall already has a trilaminar appearance and consists of: (1) a ventricular zone of high cell-packing density; (2) an intermediate zone; (3) the cortical plate (in a stage of primary consolidation) with high MRI signal intensity. The anlage of the hippocampus is present as a prominent bulging in the thin limbic telencephalon. The early fetal telencephalon impar also contains the first commissural fibers and fornix bundles in the septal area. The ganglionic eminence is clearly visible as an expanded continuation of the proliferative ventricular zone. The basal ganglia showed an ...

2006-02-01

158

The use of magnetic resonance imaging for diagnosis and staging of renal cell carcinoma  

International Nuclear Information System (INIS)

The use of magnetic resonance imaging for diagnosis and the preoperative staging of renal cell carconoma was evaluated in 79 patients with 88 tumors. Gradient-echo and spin-echo images before and after intravenous administration of Gadolinium DTPA were compared with the results of computed tomography (CT) and histologic staging. The two imaging techniques had comparable results: T-stage was predicted correctly with CT in 78%.4% and with MRI in 84.0% of the cases, while the N-stage was accurately assessed in 81.8% and 79.5%, respectively. MRI had some advantages in diagnosing perirental tumor spread and in excluding an infiltration beyond Gerota's fascia. Therefore, MRI is a true alternative to CT for staging large renal cell carcinomas and especially for patients with contraindications for iodinated contrast agents. (orig.).

159

Steady particulate flows in a horizontal rotating cylinder  

Energy Technology Data Exchange (ETDEWEB)

Results of discrete element method (DEM) simulation and magnetic resonance imaging (MRI) experiments are compared for monodisperse granular materials flowing in a half-filled horizontal rotating cylinder. Because opacity is not a problem for MRI, a long cylinder with an aspect ratio {approximately}7 was used and the flow in a thin transverse slice near the center was studied. The particles were mustard seeds and the ratio of cylinder diameter to particle diameter was approximately 50. The parameters compared were dynamic angle of repose, velocity field in a plane perpendicular to the cylinder axis, and velocity fluctuations at rotation rates up to 30 rpm. The agreement between DEM and MRI was good when the friction coefficient and nonsphericity were adjusted in the simulation for the best fit. {copyright} {ital 1998 American Institute of Physics.}

1998-06-01

160

Refrigerator operating experience on whole body MRI magnet systems  

International Nuclear Information System (INIS)

Several refrigerators for liquid helium and liquid nitrogen systems have been integrated successfully into IGC manufactured whole body Magnetic Resonance Imaging (MRI) magnet systems. The refrigerators have been tested in systems with magnetic fields of 0.6T to 1.5T. Tests were performed to study the effectiveness of the refrigerators, the magnetic field effects on the refrigerators, the effect of the refrigerators on the field uniformity and magnetic resonance image quality. The interface between the refrigerator and the whole body MRI magnet system cryostat was specifically designed to allow retrofit to the existing IGC magnet systems, while ensuring good heat transfer characteristics and good vibration isolation from the cryostat. The interface between the refrigerator and the cryostat and the refrigerator test results are presented.

1985-08-01

161

Inflammatory spine disease as a cause of back pain  

International Nuclear Information System (INIS)

The aim of this review is to evaluate the role of inflammatory spine disease in patients with chronic back pain. The contribution of imaging modalities for the diagnostic evaluation of back pain is discussed. A systematic literature search based on the classification of seronegative spondyloarthropathies and rheumatoid arthritis was performed. The results of this search and the experiences in a large collective of rheumatological patients are analyzed. The prevalence of rheumatoid arthritis (1-2%) is comparable to that of spondyloarthropathies (1.9%). The etiology of these entities is not fully elucidated. Magnetic resonance imaging is increasingly used for early detection and surveillance of therapy with TNF-#alpha# antagonists. Bone marrow edema, which is only detectable with MRI, represents an early sign of inflammation. Therapy with TNF-#alpha# antagonists is based on clinical and laboratory criteria, and signs of inflammation in MRI. ...

2006-06-01

162

Fetal MRI of pathological brain development  

International Nuclear Information System (INIS)

Because of the superior tissue contrast, high spatial resolution, and multiplanar capabilities, fetal magnetic resonance imaging (MRI) can depict fetal brain pathologies with high accuracy. Pathological fetal brain development may result from malformations or acquired conditions. Differentiation of these etiologies is important with respect to managing the actual pregnancy or counseling future pregnancies. As a widened ventricular system is a common hallmark of both maldevelopment and acquired conditions, it may cause problems in the differential diagnosis. Fetal MRI can provide detailed morphological information, which allows refinement of the diagnosis of ventricular enlargement in a large number of cases. Systematic work-up of morphological details that may be recognized on MR images provides an approach for achieving a correct diagnosis in cases of ventricle enlargement. (orig.)

2006-02-01

163

Early diagnosis of skeletal disorders in childhood and adolescence by MRI; Fruehdiagnose orthopaedischer Erkrankungen des Kindes- und Jugendalters mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

The early diagnosis of such disorders is of major importance because, in most cases, severe consequences can only be averted by early treatment. The value of magnetic resonance imaging (MRI) in many orthopaedic and traumatological conditions is generally accepted. The value of MRI in this particular field is illustrated by typical case reports on common clinical problems [Deutsch] Der Fruehdiagnose von Erkrankungen des Kindes- und Jugendalters kommt grosse Bedeutung zu, da oftmals nur durch eine daraus resultierende Fruehbehandlung schwerwiegende Folgen vermieden werden koennen. Die Kernspintomographie (Magnetresonanztomographie=MRT) ist in zahlreichen orthopaedischen-traumatologischen Fragestellungen bereits etabliert. An ausgewaehlten Fallbeispielen haeufiger klinischer Problemstellungen soll in der vorliegenden Arbeit der Stellenwert der MRT dargestellt werden. (orig.)

1998-09-18

164

A novel method for quantifying scanner instability in fMRI  

British Library Electronic Table of Contents (United Kingdom)

Abstract A method was developed to quantify the effect of scanner instability on functional MRI data by comparing the instability noise to endogenous noise present when scanning a human. The instability noise was computed from agar phantom data collected with two flip angles, allowing for a separation of the instability from the background noise. This method was used on human data collected at four 3 T scanners, allowing the physiological noise level to be extracted from the data. In a -well-operating- scanner, the instability noise is generally less than 10% of physiological noise in white matter and only about 2% of physiological noise in cortex. This indicates that instability in a well-operating scanner adds very little noise to functional MRI results. This new method allows researcher...

2011-01-01

165

Primary Ewing's sarcoma of the vertebral column  

International Nuclear Information System (INIS)

To determine the demographics, imaging findings, clinical symptoms, and prognosis of primary vertebral Ewing's sarcoma (PVES). A retrospective review of medical records and radiological studies of patients diagnosed with PVES from 1936 through 2001 in our institution and Department of Pathology consultation files was undertaken. Metastatic and soft tissue Ewing's sarcoma cases were excluded. From a total of 1,277 cases of Ewing's sarcoma, 125 (9.8%) had a primary vertebral origin. There were 48 females and 76 males. Patient ages ranged from 4 to 54 (mean 19.3, standard deviation 10.7, median 16) years. Vertebral column distribution was four cervical (3.2%), 13 thoracic (10.5%), 31 lumbar (25%), and 67 sacrum (53.2%). More than one vertebral segment was involved in ten cases (8%). Satisfactory imaging studies were available in 51 patients: 49 radiographs, 27 computerized tomography (CT), and 23 magnetic resonance imaging (MRI) studies. The ...

2004-09-01

166

Magnetic resonance imaging of the urogenital diaphragma in comparison with conventional histomorphological findings (the controversy about the deep transverse muscle of perineum); Kernspintomographische Untersuchungen des Diaphragma urogenitale im Vergleich mit korrespondierenden histomorphologischen Befunden (der Streit um den Misculus transversus perinei profundus)  

Energy Technology Data Exchange (ETDEWEB)

The transversus perinei profundus muscle is a well known structure in found anatomical textbook. Fibres of this muscle are believed to form the so-called external urethral sphincter (musculus sphincter urethrae). Recently histomorphologic investigations have shown that there is no muscular connection between the musculus sphincter urethrae (external sphincter) and the muscle system of the pelvic floor. Furthermore, the external sphincter was found to be divided into parts: The transversely striated part (musculus sphincter urethrae transversostriatus) and the smooth part (musculus sphincter urethrae glaber). Similar to histomorphologic investigations, contrast-enhanced MR imaging has shown the musculus sphincter urethrae to be surrounded by fatty and connective tissue only. Neither in MRI nor in anatomical slices can any connection between the urethral sphincter and the muscle system of the pelvic floor be found. Thus, on the basis of the results presented in this ...

1997-01-01

167

Aortic non communicating dissections. A study with helical CT  

International Nuclear Information System (INIS)

The evaluate the signs of aortic intramural hematoma with helical CT and the diagnostic role of this technique in patients with this condition. It was reviewed the CT findings of 396 patients submitted to emergency examinations for suspected aortic dissection from 1995 to 1999. Only 18 patients (6 women and 12 men) had CT signs of aortic intramural hematoma. Helical CT studies were carried out with the following parameters: slice thickness 10 mm, reconstruction index 10, feed 1.5 mm, conventional algorithm with minimum values of 130 kV and 125mA. All patients were examined with dynamic contrast-enhanced CT, before and after a power injection of 130 mL ionic contrast material. It was studied: hematoma localization and longitudinal extension; thickness and density of aortic wall; presence and location of intimal calcifications; integrity of intimal wall; hemo mediastinum and/or hemo thorax. Aortic wall thickening appeared as a high density crescent-shaped area at ...

2000-09-01

168

Medical treatment of nystagmus and ocular motor disorders.  

Science.gov (United States)

An increased compendium of drugs useful in ocular motor system dysfunction has expanded our capacity to treat selected ocular motility disorders. Adjunctive therapeutic modes (e.g., Fresnel prisms and orthoptic exercises) can also be beneficial. PAN and see-saw nystagmus can be treated with baclofen. Downbeat nystagmus may respond to clonazepam therapy, and prisms may help if the nystagmus can be modified with convergence. Congenital nystagmus may respond minimally to drugs (e.g., baclofen), but prisms or surgical procedures, or both, are still the primary treatment modalities. Innovar may be helpful in patients with severe, incapacitating vestibular disorders, and scopolamine alone or in combination with promethazine may be beneficial in patients with milder ambulatory acute peripheral vestibular disorders. Benign positional vertigo is best treated initially with positional exercises before drug therapy is instituted. Opsoclonus and ocular flutter have been treated successfully with ...

1986-01-01

169

The Influence of Moderate Hypercapnia on Neural Activity in the Anesthetized Nonhuman Primate  

UK PubMed Central (United Kingdom)

Hypercapnia is often used as vasodilatory challenge in clinical applications and basic research. In functional magnetic resonance imaging (fMRI), elevated CO2 is applied to derive stimulus-induced...Full Text Available

2008-11-01

170

Segmentation of Myocardial Boundaries in Tagged Cardiac MRI Using Active Contours: A Gradient-Based Approach Integrating Texture Analysis  

UK PubMed Central (United Kingdom)

The noninvasive assessment of cardiac function is of first importance for the diagnosis of cardiovascular diseases. Among all medical scanners only a few enables radiologists to evaluate the local cardiac...Full Text Available

2009-01-01

171

Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body  

UK PubMed Central (United Kingdom)

BackgroundMagnetic Resonance Imaging scanners have become ubiquitous in hospitals and high-field systems (greater than 3 Tesla) are becoming increasingly common. In light of recent...Full Text Available

172

Normal and abnormal water diffusion in the brain  

International Nuclear Information System (INIS)

Diffusion magnetic resonance imaging (MRI) has become an important tool in the radiologic diagnosis of diseases of the brain as it measures molecular motion of water that characterizes the microstructure of tissues. Its most important clinical use to date is the early detection of cerebral ischemia by revealing the ischemic injury shortly after vessel occlusion and simultaneously providing therapy-relevant information on the tissue at risk. Furthermore, diffusion MRI is diagnostically promising in other diseases of the brain and is thus increasingly becoming part of routine clinical protocols in the diagnosis of tumors, inflammation, trauma, demyelination, dysmyelination and neurodegeneration. Although abnormalities of diffusion are generally not pathognomonic, diffusion MRI affords information about tissue changes for specific disorders that complements information obtained with standard MR techniques and frequently shows ...

2003-10-01

173

Non-white noise in fMRI: does modelling have an impact?  

DEFF Research Database (Denmark)

The sources of non-white noise in Blood Oxygenation Level Dependent (BOLD) functional magnetic resonance imaging (fMRI) are many. Familiar sources include low-frequency drift due to hardware imperfections, oscillatory noise due to respiration and cardiac pulsation and residual movement artefacts not accounted for by rigid body registration. These contributions give rise to temporal autocorrelation in the residuals of the fMRI signal and invalidate the statistical analysis as the errors are no longer independent. The low-frequency drift is often removed by high-pass filtering, and other effects are typically modelled as an autoregressive (AR) process. In this paper, we propose an alternative approach: Nuisance Variable Regression (NVR). By inclusion of confounding effects in a general linear model (GLM), we first confirm that the spatial distribution of the various fMRI noise sources is similar to what has already been ...

2005-01-01

174

Non-white noise in fMRI: Does modelling have an impact?  

DEFF Research Database (Denmark)

The sources of non-white noise in Blood Oxygenation Level Dependent (BOLD) functional magnetic resonance imaging (fMRI) are many. Familiar sources include low-frequency drift due to hardware imperfections, oscillatory noise due to respiration and cardiac pulsation and residual movement artefacts not accounted for by rigid body registration. These contributions give rise to temporal autocorrelation in the residuals of the fMRI signal and invalidate the statistical analysis as the errors are no longer independent. The low-frequency drift is often removed by high-pass filtering, and other effects are typically modelled as an autoregressive (AR) process. In this paper, we propose an alternative approach: Nuisance Variable Regression (NVR). By inclusion of confounding effects in a general linear model (GLM), we first confirm that the spatial distribution of the various fMRI noise sources is similar to what has already been ...

2006-01-01

175

Measurement of the quadriceps femoris muscle using magnetic resonance and ultrasound imaging.  

UK PubMed Central (United Kingdom)

OBJECTIVES: To define a method for measurement of the cross sectional area and volume of the quadriceps femoris muscle using magnetic resonance imaging (MRI) in conjunction with stereology, and to compare...Full Text Available

1997-03-01

176

Mapping strain exerted on blood vessel walls using deuterium double-quantum-filtered MRI  

UK PubMed Central (United Kingdom)

A technique is described for displaying distinct tissue layers of large blood vessel walls as well as measuring their mechanical strain. The technique is based on deuterium double-quantum-filtered (DQF)...Full Text Available

1998-04-14

177

Magnetic resonance imaging in acute intractional tuberculosis; Magnetresonanztomographie bei akuter intrakranieller Tuberkulose  

Energy Technology Data Exchange (ETDEWEB)

We reported three cases of acute intracranial tuberculosis including miliary tuberculosis, basal meningitis, tuberculomas and neuritis of cranial nerves. All patients had native and contrast enhanced CT and MRI scans. MRI revealed more granulomas and a better imaging contrast in the detection of basal meningitis. Neuritis was diagnosed only with the MRI. MRI scans should be prefered as the imaging procedure in clinically presumed intracranial tuberculosis. (orig.) [Deutsch] Die Befunde von drei Patienten mit intrakranieller Tuberkulose (intrakranielle Miliartuberkulose, Meningitis tuberculosa, Neuritis und Tuberkulome) in der Magnetresonanztomographie (MRT) wurden mit der Computertomographie (CT) verglichen. Sowohl die MRT als auch die CT wurden nativ und nach Kontrastmittelgabe durchgefuehrt. Die MRT zeigte sich im Nachweis von Granulomen insbesondere im Bereich des Hirnstamms ueberlegen. Ebenso wurde ...

1994-12-31

178

MRI classification of interspinous ligament degeneration of the lumbar spine: intraobserver and interobserver reliability and the frequency of disagreement  

UK PubMed Central (United Kingdom)

Posterior spinal ligament pathology is becoming increasingly recognized as a significant cause of low back pain. Despite the growing clinical importance of interspinous ligament degeneration in low...Full Text Available

2010-10-01

179

Interictal Functional Connectivity of Human Epileptic Networks Assessed by Intracerebral EEG and BOLD Signal Fluctuations  

UK PubMed Central (United Kingdom)

In this study, we aimed to demonstrate whether spontaneous fluctuations in the blood oxygen level dependent (BOLD) signal derived from resting state functional magnetic resonance imaging (fMRI) reflect...Full Text Available

180

Functional Impact of White Matter Hyperintensities in Cognitively Normal Elderly  

UK PubMed Central (United Kingdom)

ObjectiveTo investigate the impact white matter hyperintensities (WMH) detected on MRI have on motor dysfunction and cognitive impairment in non-demented elderly...Full Text Available

2010-11-01

181

Focal structural changes and cognitive dysfunction in juvenile myoclonic epilepsy  

UK PubMed Central (United Kingdom)

Objective:The aim of this study was to determine if there were focal cortical abnormalities in juvenile myoclonic epilepsy (JME) using neuropsychological investigations and MRI.Methods:Twenty-eight...Full Text Available

2011-01-04

182

Evaluation of fetal brain development by magnetic resonance imaging. Subependymal germinal matrix layer and cerebral ventricle  

International Nuclear Information System (INIS)

Three dimensional data of brain from the formalin-fixed fetuses were collected without isolation, by the 4.7 tesla super high magnetic field MRI and the developmental process of the cerebral parenchyma was studied by 3D images. Subjects were 13 fetal brain and MRI was performed using 3D-steady-state free precession sequence. The isolated brain is very soft and fragile and is deformed by its weight at the imaging. However 3D-MRI can be obtained without isolation, and the deformation is remarkably small. The subependymal germinal matrix layer did not be observed in 7 weeks-old fetus, appeared at 9 weeks-old and increased gradually. Then it rapidly reduced from 28 weeks-old. The volume calculated, from 3D-MRI, increased rapidly from 9 weeks-old to 23 weeks-old, and reached the maximum (2.346 mm"3) at 23 weeks-old. The relation between fetal ages and volume of cerebral ventricle also showed similar pattern. ...

1999-10-01

183

Evaluation of femoral head perfusion by dynamic MRI  

International Nuclear Information System (INIS)

The purpose of this study was to evaluate the usefulness of dynamic MRI for femoral head perfusion. Objects were 64 femoral heads of 44 normal cases (20-95 years old), 10 cases (33-90 y) of femoral neck fracture and 8 cases (61-86 y) using steroid due to articular rheumatism, nephrosis and other diseases. Siemens 1.0 T Magneton Impact with body array coil was used for dynamic MRI by the fast low-angle shot 2D method for every 17 sec interval. Gd-DTPA was injected intravenously. ROI was defined in the center of femur head and of trochanter to monitor their values for the dynamic curve. Evaluation was done on the ratio of enhancement ratio (ER) in the head/trochanter and on the curve in both heads. In normal cases, the head ER was significantly lower in >60 years old cases. There was neither significant correlation between their head/trochanter ER ratios nor significant difference between their dynamic curves. In fracture cases, there were ...

1998-05-01

184

Enhancing fraction measured using dynamic contrast-enhanced MRI predicts disease-free survival in patients with carcinoma of the cervix  

UK PubMed Central (United Kingdom)

Background:There is a need for simple imaging parameters capable of predicting therapeutic outcome.Methods:This retrospective study analysed 50 patients...Full Text Available

2010-01-05

185

Dynamic NMR effects in breast cancer dynamic-contrast-enhanced MRI  

UK PubMed Central (United Kingdom)

The passage of a vascular-injected paramagnetic contrast reagent (CR) bolus through a region-of-interest affects tissue 1H2O relaxation and thus MR image intensity. For longitudinal...Full Text Available

2008-11-18

186

Delineation of the Middle Longitudinal Fascicle in Humans: A Quantitative, In Vivo, DT-MRI Study  

UK PubMed Central (United Kingdom)

Experimental and imaging studies in monkeys have outlined various long association fiber bundles within the temporoparietal region. In the present study the trajectory of the middle longitudinal fascicle...Full Text Available

2009-04-01

187

Convection-enhanced delivery of maghemite nanoparticles: Increased efficacy and MRI monitoring  

UK PubMed Central (United Kingdom)

Convection-enhanced drug delivery (CED) is a novel approach to delivering drugs into brain tissue. Drugs are delivered continuously via a catheter, enabling large volume distributions of high drug concentrations...Full Text Available

2008-04-01

188

Comprehensive Approach to Arthroscopic Rotator Cuff Repair: Options and Techniques  

Medline Plus

... and at that point she had already failed physical therapy, which someone else had prescribed, and so ... MRI, we may try a brief course of physical therapy to see if they feel better, but ...

189

Combining fMRI with EEG and MEG in order to relate patterns of brain activity to cognition  

UK PubMed Central (United Kingdom)

The common factor that underlies several types of functional brain imaging is the electric current of masses of dendrites. The prodigious demands for the energy that is required to drive the...Full Text Available

2009-07-01

190

Characteristics of common solid liver lesions and recommendations for diagnostic workup  

UK PubMed Central (United Kingdom)

Due to the widespread clinical use of imaging modalities such as ultrasonography, computed tomography and magnetic resonance imaging (MRI), previously unsuspected liver masses are increasingly being...Full Text Available

2009-07-14

191

Catheter Ablation for Paroxysmal Atrial Fibrillation  

Medline Plus

... catheter ablation for paroxysmal atrial fibrillation procedure utilizing 3-D mapping and rotational intracardiac echocardiography. This program is ... of the MRI scan and then there's the 3-D image, which is generated from the pixels chosen ...

192

Bone stress injury of the ankle in professional ballet dancers seen on MRI  

UK PubMed Central (United Kingdom)

BackgroundBallet Dancers have been shown to have a relatively high incidence of stress fractures of the foot and ankle. It was our objective to examine MR imaging patterns of bone...Full Text Available

193

Assessment of the value of various tomography modalities for diagnostic evaluation of the female genital system  

International Nuclear Information System (INIS)

The comprehensive survey explains the indications and the specific value of the modern tomographic modalities with respect to the various diagnostic issues. Numerous reproductions of CT, MRI, US scans illustrate the aspects discussed. (orig./CB)

2001-09-01

194

Assessment of PET and MRI Polar Map using Gaussian Mixture Model  

International Nuclear Information System (INIS)

Cardiac disease research relies increasingly on small animal models and non-invasive imaging methods such as positron emission tomography (PET) and magnetic resonance imaging (MRI). Delayed enhancement magnetic resonance imaging (DE-MRI) using gadolinium-based contrast agents appear to be a visualizing infracted myocardium with high spatial resolution. Polar map (or bull's-eye image) was used to determination of the myocardial infarction area. Polar map is a comprehensive interpretation of the left ventricle. The infarct size was computed as the fraction of the total polar map areas. The threshold was computed as the percentage of mean intensity of the normal region. In other study, 50% predefined threshold value in varying range (30?70%) was most commonly use. However, predefined threshold value isn't acceptance in all case. The purpose of this study was to investigate methodological approach for automatic measurement of rat myocardial infarct ...

2010-10-01

195

Assessing and Compensating for Zero-lag Correlation Effects in Time-lagged Granger Causality Analysis of fMRI  

UK PubMed Central (United Kingdom)

Effective connectivity in brain networks can be studied using Granger causality analysis which is based on temporal precedence, while functional connectivity is usually derived using zero-lag...Full Text Available

2010-06-01

196

Quantification of cardiac function with multislice spiral CT using retrospective EKG-gating: comparison with MRI  

International Nuclear Information System (INIS)

Purpose: To quantify left ventricular function derived from retrospectively ECG-gated multislice spiral CT (MSCT) data sets in comparison to MRI. Materials and Methods: In 16 patients (14 males, 2 females, mean age 56.8 #+-# 11.5 years), retrospectively ECG-gated MSCT angiography of the coronary arteries and breath-hold steady state free precession cine MRI were performed. From MSCT data-sets, 20 axial image series were reconstructed every 5% of the RR interval. Multiplanar images were reformatted in the short axis orientation from axial images. End-systolic and end-diastolic images were selected. From these images end-systolic volume (ESV), end-diastolic volume (EDV) and stroke volume (SV) as well as the ejection fraction (EF) and myocardial mass (MM) were determined using the Simpson's method and compared with MRI. Furthermore, image quality was assessed for both imaging modalities using a four point grading scale. ...

2003-01-01

197

MRI-based N-staging in esophageal cancer  

International Nuclear Information System (INIS)

Purpose: For planning the therapeutic strategies and estimating the prognosis in esophageal cancer, N-staging is very important. To date, MRI still is of minor importance as imaging modality of the mediastinum despite promising developments in the past, like ECG-gating or 'averaging' sequences, e.g. LOTA (Long-term averaging), which facilitate mediastinal and thoracic MR-imaging. In a prospective approach, the value of MRI based N-staging was examined with respect to LOTA-sequences. Material and Methods: Within from weeks prior to esophagectomy, standardized MRI of the esophagus was performed in 15 patients (10 squamous-cell-carcinomas and 5 adenocarcinomas) using a 1.5 T whole body scanner. Imaging quality was classified based on depiction of aortic wall or tracheal wall layers. Criteria for malignant infiltration were a diameter of more than 15 mm or a round appearance of a lymph node together with GD-DTPA enhancement. ...

2002-10-01

198

Hypercapnic normalization of BOLD fMRI: comparison across field strengths and pulse sequences.  

DEFF Research Database (Denmark)

The blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) signal response to neural stimulation is influenced by many factors that are unrelated to the stimulus. These factors are physiological, such as the resting venous cerebral blood volume (CBV(v)) and vessel size, as well as experimental, such as pulse sequence and static magnetic field strength (B(0)). Thus, it is difficult to compare task-induced fMRI signals across subjects, field strengths, and pulse sequences. This problem can be overcome by normalizing the neural activity-induced BOLD fMRI response by a global hypercapnia-induced BOLD signal. To demonstrate the effectiveness of the BOLD normalization approach, gradient-echo BOLD fMRI at 1.5, 4, and 7 T and spin-echo BOLD fMRI at 4 T were performed in human subjects. For neural stimulation, subjects performed sequential finger movements at 2 ...

2004-01-01

199

Diffusion and perfusion MR imaging in stroke; MR-Diffusion und -Perfusion beim Schlaganfall  

Energy Technology Data Exchange (ETDEWEB)

Magnetic resonance imaging (MRI) in stroke makes it possible to visualize the initial infarct in cases of acute cerebral ischemia. Perfusion MRI serves to determine which tissues are additionally at risk of infarction due to persistent hypoperfusion. MRI also allows those examiners with limited experience to reliably confirm an infarct. The most important differential diagnosis of cerebral ischemia, intracerebral hemorrhage, can likewise be recognized with certainty using MRI. Although diffusion and perfusion MRI only demonstrate the pathophysiology of cerebral ischemia approximately, the method is suited for identifying those patients who would profit from reperfusion therapy. Whether MRI is also appropriate as an aid to reaching a prognosis on the risk of secondary hemorrhage has not yet been resolved. (orig.) [German] Die Schlaganfall-MRT ermoeglicht es, bei ...

2005-05-01

200

Anatomical changes after radical surgery and reconstruction with pedunculated or revascularized flaps in advanced head and neck cancer: CT and MR features; Modificazioni anatomiche dopo chirurgia radicale e ricostruzione con lembi peduncolati o rivascolarizzati nei tumori cervico-facciali negli stadi avanzati: Aspetti con Tomografia Computerizzata e Risonanza Magnetica  

Energy Technology Data Exchange (ETDEWEB)

January, 1992, to October, 1995, sixty-four patients with advanced head and neck cancer underwent head and neck reconstructive surgery using myocutaneous or revascularized flaps; in the same period, all patients were consecutively examined with CT and MRI. Myocutaneous flaps were used in 26 patients: 12 flaps were tubular and 14 linear. Revascularized flaps were used in 38 patients: to repair a large defect in 26 patients (14 latissimus dorsi flaps and 12 temporal muscle flaps) and to repair an oral damage in 12 patients (5 revascularized radial and 7 jejunal flaps). CT and MR images of myocutaneous flaps showed the flaps as fatty areas, repairing large surgical defects, hypodense at CT and hyperintense at MRI, with no post-contrast enhancement. The appearance of revascularized flaps at CT and MRI depends on the characteristics of the structure used to repair the surgical defect: jejunal and radial flaps appeared as mostly ...

1997-04-01

201

Anatomical changes after radical surgery and reconstruction with pedunculated or revascularized flaps in advanced head and neck cancer: CT and MR features  

International Nuclear Information System (INIS)

January, 1992, to October, 1995, sixty-four patients with advanced head and neck cancer underwent head and neck reconstructive surgery using myocutaneous or revascularized flaps; in the same period, all patients were consecutively examined with CT and MRI. Myocutaneous flaps were used in 26 patients: 12 flaps were tubular and 14 linear. Revascularized flaps were used in 38 patients: to repair a large defect in 26 patients (14 latissimus dorsi flaps and 12 temporal muscle flaps) and to repair an oral damage in 12 patients (5 revascularized radial and 7 jejunal flaps). CT and MR images of myocutaneous flaps showed the flaps as fatty areas, repairing large surgical defects, hypodense at CT and hyperintense at MRI, with no post-contrast enhancement. The appearance of revascularized flaps at CT and MRI depends on the characteristics of the structure used to repair the surgical defect: jejunal and radial flaps appeared as mostly ...

1997-01-01

204

Multi-modality imaging of uveal melanomas using combined PET/CT, high-resolution PET and MR imaging  

Energy Technology Data Exchange (ETDEWEB)

We investigated the efficacy of combined FDG-PET/CT imaging for the diagnosis of small-size uveal melanomas and the feasibility of combining separate, high-resolution (HR) FDG-PET with MRI for its improved localization and detection. Patients, methods: 3 patients with small-size uveal melanomas (0.2-1.5 ml) were imaged on a combined whole-body PET/CT, a HR brain-PET, and a 1.5 T MRI. Static, contrast-enhanced FDG-PET/CT imaging was performed of head and torso with CT contrast enhancement. HR PET imaging was performed in dynamic mode 0-180 min post-injection of FDG. MRI imaging was performed using a high-resolution small-loop-coil placed over the eye in question with T2-3D-TSE and T1-3D-SE with 18 ml Gd-contrast. Patients had their eyes shaded during the scans. Lesion visibility on high-resolution FDGPET images was graded for confidence: 1: none, 2: suggestive, 3: clear. Mean tumour activity was calculated for summed image ...

2008-07-01

205

Ganglioneuromas in childhood: MRI and CT characteristics; Ganglioneurome im Kindesalter: CT- und MRT-Charakteristika  

Energy Technology Data Exchange (ETDEWEB)

Purpose: The aim of this study was to demonstrate the typical appearance of ganglioneuromas in computer-assisted tomography (CT), and magnetic resonance imaging (MRI). Material and methods: Retrospective analysis of diagnostic imaging (9 CT, 6 MRI) in 9 children aged 3 to 15 years with the histological diagnosis of ganglioneuroma. Results: The tomographies showed large (max. 13.4 cm in diameter) round or oval tumors with sharp delineation. The sites of the tumors were the retroperitoneum (5), the mediastinum (3), and the adrenal gland (1). Intraspinal tumor involvement occurred in 4 cases. On comparing CT with MRI, MRI was more accurate in defining the intraspinal involvement. The ganglioneuromas were of hypodense appearance in the native CT scan and showed moderate enhancement upon administration of contrast media. In five patients tumor calcifications with a disseminated sprinkled pattern were seen in ...

2000-05-01

206

Lacrimal gland masses on CT and MRI: a report of four cases; Raumforderungen der Traenendruese in CT und MRT am Beispiel von vier Faellen  

Energy Technology Data Exchange (ETDEWEB)

In an extended case report, we discuss four cases with masses in the lacrimal fossa representing the most important entities in this region (lymphoma, pleomorphadenoma, inflammatory pseudotumor, and malignant epithelial tumor). The different indications for CT and MRI are explained. For the differential diagnosis of lacrimal gland lesions, the following imaging parameters are important: The shape of the lacrimal gland, the inner structure, the degree of contrast enhancement, and the surrounding bony structures. In the evaluation of the expansion of lacrimal gland lesions, CT in thin slices with multiplanar reconstructions is equal to MRI. However, the contrast-enhancement of lacrimal glands is better evaluated with MRI than with CT. The bony structures are better visualized on CT than on MRI. (orig.) [Deutsch] In einem erweiterten Fallbericht wird ueber die vier grossen Entitaeten bei ...

1995-11-01

207

High-field MR imaging in the follow-up of patients with valvular and composite tubular aortic prostheses  

International Nuclear Information System (INIS)

Eleven patients who had undergone cardiac surgery were studied by means of high-field MR imaging (1.5 T). Six patients had aortic root and valve replaced with a Bjork-Shiley (BS) composite tubular aortic graft prosthesis for acute dissection of ascending aorta. In the other 5 patients with rheumatic calcific aortic disease, the valve had been replaced with a BS prosthesis. As a whole, MR studies were 14. Previous evaluations of magnetic field effects had seem carried out ex vivo on both BS valves and BS composite prostheses, on surgical ligation clips (Tantalium and Stainless) and on stainless wires for sternal closure. In 4 patients (2 BS composite grafts, and 2 BS valves) MRI diagnosed chronic dissection of both arch and descending aorta. In 1 of them, with a bs valve, associated localized acute dissection of ascending aorta was observed. In 3 patients with BS composite grafts, MRI revealed pseudo-aneurysms (including a thrombosed one) at the ...

208

Benign diseases of the mandible in MRI; Benigne Erkrankungen des Unterkiefers im MRT  

Energy Technology Data Exchange (ETDEWEB)

Diseases of the mandible affect the soft tissues aside from the osseous manifestation. This can be shown clearly and in great detail by magnetic resonance imaging (MRI). MRI is the gold standard in the diagnostic evaluation of any internal derangement of the temporomandibular joint. Dental MRI requires high resolution techniques and in some cases also intravenous administration of contrast material. These techniques allow delineation of the neurovascular bundle. In the past few years new indications were formulated, for example, the evaluation of the integrity of the inferior alveolar nerve in trauma and in radicular cysts. New quantitative methods now enable insights into the pathophysiology. The objective of this review is to communicate accepted indications for MRI of the mandible and to present innovative applications. (orig.) [German] Mandibulaere Erkrankungen beteiligen neben dem Knochen ...

2004-04-01

209

Ultrashort echo time MRI of cortical bone at 7 tesla field strength: A feasibility study  

British Library Electronic Table of Contents (United Kingdom)

AbstractPurpose: To implement and examine the feasibility of a three-dimensional (3D) ultrashort TE (UTE) sequence on a 7 Tesla (T) clinical MR scanner in comparison with 3T MRI at high isotropic resolution. Materials and Methods: Using an in-house built saddle coil at both field strengths we have imaged mid-diaphysial sections of five fresh cadaveric specimens of the distal tibia. An additional in vivo scan was performed at 7 Tesla using a quadrature knee coil. Results: Using the same type of saddle coil at both field strengths, a significant increase in SNR at 7T compared with 3T (factor 1.7) was found. Significantly shorter T2* values were found at the higher field strength (T2* = 552.2 126 s at 7T versus T2* = 1163 391 s at 3T). Conclusion: UHF MRI at 7T has great potential for imaging...

2011-01-01

210

T{sub 1} and T{sub 2} relaxivities of succimer-coated MFe{sub 2}{sup 3+}O{sub 4} (M=Mn{sup 2+}, Fe{sup 2+} and Co{sup 2+}) inverse spinel ferrites for potential use as phase-contrast agents in medical MRI  

Energy Technology Data Exchange (ETDEWEB)

Superparamagnetic MFe{sub 2}{sup 3+}O{sub 4} (M=Mn{sup 2+}, Fe{sup 2+} and Co{sup 2+}) inverse spinel ferrite (ISF) nanoparticles with narrow size distribution having average diameters of 6-8 nm were synthesized by a diol reduction of organic metals and the surface was modified to be hydrophilic by coating with succimer. Magnetic resonance imaging (MRI) contrast enhancement by dipolar coupling defined interactions between the synthesized ISFs and protons in the bulk water was investigated with initial susceptibility, magnetization and anisotropy of the succimer-coated ISFs. The relaxivity ratios, r{sub 2}/r{sub 1}, for MnFe{sub 2}O{sub 4}, Fe{sub 3}O{sub 4} and CoFe{sub 2}O{sub 4} were measured to be 12.2, 23.1 and 62.3, respectively, which demonstrate the potential usefulness of these magnetic nanoparticles as T{sub 2} contrast agents for MRI.

2009-12-15

211

T1 and T2 relaxivities of succimer-coated MFe23+O4 (M=Mn2+, Fe2+ and Co2+) inverse spinel ferrites for potential use as phase-contrast agents in medical MRI  

International Nuclear Information System (INIS)

Superparamagnetic MFe23+O4 (M=Mn2+, Fe2+ and Co2+) inverse spinel ferrite (ISF) nanoparticles with narrow size distribution having average diameters of 6-8 nm were synthesized by a diol reduction of organic metals and the surface was modified to be hydrophilic by coating with succimer. Magnetic resonance imaging (MRI) contrast enhancement by dipolar coupling defined interactions between the synthesized ISFs and protons in the bulk water was investigated with initial susceptibility, magnetization and anisotropy of the succimer-coated ISFs. The relaxivity ratios, r2/r1, for MnFe2O4, Fe3O4 and CoFe2O4 were measured to be 12.2, 23.1 and 62.3, respectively, which demonstrate the potential usefulness of these magnetic nanoparticles as T2 contrast agents for MRI.

2009-12-01

212

MRI in combined subacute degeneration of the spinal cord; MRT bei funikulaerer Myelose  

Energy Technology Data Exchange (ETDEWEB)

The MRI morphology in combined subacute degeneration has only rarely been reported. We describe two patients suffering from subacute combined degeneration of the spinal cord on the basis of a deficiency of vitamin B{sub 12}. In both patients characteristic hyperintense areas on T{sub 2}-weighted images in the posterior columns of the cervical and thoracic cord without contrast enhancement were demonstrated by MRI. (orig.) [Deutsch] Bisher liegen zur wenige Beschreibungen der MR-Morphologie bei funikulaerer Myelose vor. Wir beschreiben zwei Patienten mit den klinischen Zeichen einer funikulaeren Myelose auf der Basis eines Vitamin B{sub 12}-Mangels. Bei beiden konnten mit der MRT charakteristische Signalanhebungen im T{sub 2}-gewichteten Bild in den Hinterstraengen des zervikalen und thorakalen Rueckenmarks gezeigt werden. Eine Kontrastmittelaufnahme war nicht nachweisbar. (orig.)

1999-06-01

213

MR imaging of hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Magnetic resonance (MR) images of 18 cases of hilar cholangiocarcinoma were evaluated to compare the effectiveness of Gd-DTPA with that of high dose contrast enhancement computed tomography (HCE-CT) in detecting the primary tumor. The primary tumor was demonstrated as having slightly low intensity compared with liver parenchyma and high intensity compared with the delated bile duct on T1-weighted images. In contrast, MRI using Gd-DTPA, which was carried out in five cases, revealed intense enhancement of the tumor. As the differentiation between cholangiocarcinoma and dilated bile duct was difficult, it was concluded that the use of Gd-DTPA improves the efficacy of MRI in diagnosing cholangiocarcinoma. Gd-DTPA was also effective in differentiating the growth pattern of the tumor: the infiltrating type was demonstrated as thickening of the wall of the bile duct, the polypoid type as a soft tissue mass in the bile duct. Contrast ...

214

Dura thickening adjacent to intracranial tumors on MRI. Histologically correlation  

International Nuclear Information System (INIS)

Purpose: With intracranial tumors a flat, contrast-enhancing, probably dural structure adjacent to the tumor can occasionally be observed on gadolinium-DTPA enhanced MR images. Therefore we have attempted to evaluate a tumor infiltration of this enthancement on MRI. Material and Methods: This study included 50 patients. 19 patients had a dural thickening at the tumor base (13 meningiomas and 6 metastases), while 31 patients did not (12 meningiomas and 19 metastases). Studies included plane T_2-weighted spin echo (SE) images as well as T_1-weighted axial, coronal, or sagittal plains with and without contrast agent. Histopathological examinations, were done on the tumor base adjacent to the dura mater. Results: 7 of 12 meningiomas showed a meningeal thickening on MRI with histopathologically proven tumor infiltration as did also 5 of 6 metastases. But 3 of 12 meningiomas and 15 of 19 metastases without dural thickening at the tumor base also ...

215

Primary malignant lymphoma of the brain; Primaere maligne Lymphome des Gehirns  

Energy Technology Data Exchange (ETDEWEB)

Primary malignant lymphoma of the brain is a disease of unknown etiology, which is increasing in incidence and has an unfavorable prognosis. Despite the lack of specific changes on CT or MRI in most cases, these procedures may typically facilitate the diagnosis: A focal-enhancing mass with subependymal spread on CT or MRI and hyperattenuation on nonenhanced CT are the most reliable features in the diagnosis of primary malignant lymphoma of the brain. Peritumoral edema and mass effect are usually not prominent features. On unenhanced CT scans they usually appear homogeneously isodense to mildly hyperdense relative to the gray matter. On MRI these tumors are slightly hypointense on T1-weighted images and slightly hpyerintense on PD- and T2-weighted images relative to the gray matter. On CT and MRI enhancement is usually homogeneous. Contrast-enhanced MRI, with its multiplanar ...

1997-01-01

216

The influence of normal human ageing on automatic movements  

British Library Electronic Table of Contents (United Kingdom)

There is evidence that aged normal subjects have more difficulty in achieving automaticity than young subjects. The underlying central neural mechanism for this phenomenon is unclear. In the present study, functional magnetic resonance imaging (fMRI) was used to investigate the effect of normal ageing on automaticity. Aged healthy subjects were asked to practice self-initiated, self-paced, memorized sequential finger movements with different complexity until they could perform the tasks automatically. Automaticity was evaluated by having subjects perform a secondary task simultaneously with the sequential movements. Although it took more time, most aged subjects eventually performed the tasks automatically at the same level as the young subjects. Functional MRI results showed that, for bot...

2005-01-01

217

Targeted drug delivery under MRI guidance  

British Library Electronic Table of Contents (United Kingdom)

The main goal of local drug delivery is to increase the concentration of a specific therapeutic agent in a target tissue with minimal nontarget distribution. Compared to systemic therapy, local drug delivery provides a high level of therapeutic efficacy with minimal systemic effects. The current primary imaging modality for drug delivery has been x-ray angiography, but it has major limitations including anatomical ambiguity and inability to visualize the targeted tissues. Due to these inherent problems, MR guidance has been explored as an alternative imaging modality for guiding and monitoring of drug therapy. Recently, interventional MR (XMR) systems have been implemented that have both dual x-ray and MRI capabilities in a single suite and allow for real-time interventional procedures to ...

2008-01-01

218

Quantitative measurements of injections into porous media with contrast based MRI  

British Library Electronic Table of Contents (United Kingdom)

Porous flow occurs in a wide range of materials and applies to many commercially relevant applications such as oil recovery, chemical reactors and contaminant transport in soils. Typically, breakthrough and pressure curves of column floods are used in the laboratory characterization of these materials. These characterization methods lack the detail to easily and unambiguously resolve flow mechanisms with similar effects at the core scale that can dominate at the aquifer or oil field scale, as well as the effects of geometry that control the flow at interfaces as in a perforated well or the inlet of an improperly designed column. Non-invasive imaging techniques such as MRI have been shown to provide a far more detailed characterization of the properties of the solid matrix and flow, but usu...

2011-01-01

219

Parallel MRI reconstruction using variance partitioning regularization  

British Library Electronic Table of Contents (United Kingdom)

Multiple receivers can be utilized to enhance the spatiotemporal resolution of MRI by employing the parallel imaging technique. Previously, we have reported the L-curve Tikhonov regularization technique to mitigate noise amplification resulting from the geometrical correlations between channels in a coil array. Nevertheless, one major disadvantage of regularized image reconstruction is lengthy computational time in regularization parameter estimation. At a fixed noise level, L-curve regularization parameter estimation was also found not to be robust across repetitive measurements, particularly for low signal-to-noise ratio (SNR) acquisitions. Here we report a computationally efficient and robust method to estimate the regularization parameter by partitioning the variance of the noise-white...

2007-01-01

220

Magnetic separation anxiety  

International Nuclear Information System (INIS)

This paper reports that only a few years ago superconducting magnetic separation was viewed as the next major market for superconducting magnets. The first commercial units had been installed, worked flawlessly, and demonstrated real economic viability. The potential market was seen as quite large, and many people believed that superconducting magnetic separation would soon show the same rapid growth that MRI had demonstrated after its initial success. These hopes even prompted IGC, one of the top MRI magnet builders, to form a separate division devoted to magnetic separation. Despite the existence of Magstream, IGC has not been overly active in the market. As a technology that has applications from the clay on the Earth to the soil on the moon, superconducting magnetic separation has yet to become widely used.

1992-01-01

221

Magnetic resonanse imaging in otorhinolaryngology. With special reference to the influence of factors upon NMR parameters and differential diagnosis of otorhinolaryngic lesions  

Energy Technology Data Exchange (ETDEWEB)

MRI diagnosis for malignant tumors are made possible by direct comparison to the results obtained by the brain and it seems possible to differentiate malignant tumors from other benign lesions. Cystic lesions, and mycotic sinusitis sometimes resemble malignant tumors in MR Image. In the present report, we investigated the relationships between the biochemical contents of cystic lesions and NMR-parameters to clarify why some inflammatory lesions appeared similar to malignant tumors in MRI. The variation of relaxation time depends upon the amount of protein in the cystic contents and the amount of glucose affects the relaxation time. We conclude that NMR-parameters are useful for the differential diagnosis of malignant tumors, cystic lesions and mycositic sinusitis by using the multiple variation analysis.

1987-07-01

222

Impact of diagnosis by enhanced multidetector-row computed tomography and magnetic resonance imaging for extrahepatic cholangiocarcinoma  

International Nuclear Information System (INIS)

Herein we present an impact of diagnosis by enhanced multidetector-row computed tomography and magnetic resonance imaging for extrahepatic cholangiocarcinoma (ECC). Although the diagnosis against the longitudinal stromal extension and surrounding tissue invasion of ECC by multi detector row CT (MDCT) and MRI was very strict, we could not detect any superficial mucosal spread (SMS). Furthermore, the diagnosis of lymphnode metastasis by MDCT/MRI was miserable. We believe that misdiagnosis of SMS is permissible since positive mucosal but not stromal surgical margin was not a significant factor influencing the postoperative prognosis. However, further advances in imaging diagnosis for ECC is needed. (author)

2009-10-01

223

Evaluation of cortical current density imaging methods using intracranial electrocorticograms and functional MRI  

British Library Electronic Table of Contents (United Kingdom)

Objective:EEG source imaging provides important information regarding the underlying neural activity from noninvasive electrophysiological measurements. The aim of the present study was to evaluate source reconstruction techniques by means of the intracranial electrocorticograms (ECoGs) and functional MRI.Methods:Five source imaging algorithms, including the minimum norm least square (MNLS), LORETA with Lp-norm (p equal to 1, 1.5 and 2), sLORETA, the minimum Lp-norm (p equal to 1 and 1.5; when p=2, the MNLS method is mathematically equivalent to the minimum Lp-norm) and L1-norm (the linear programming) methods, were evaluated in a group of 10 human subjects, in a paradigm with somatosensory stimulation. Cortical current density (CCD) distributions were estimated from the scalp somatosensor...

2007-01-01

224

Development of a Full Body CAD Dataset for Computational Modeling: A Multi-modality Approach  

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to develop full body CAD geometry of a seated 50th percentile male. Model development was based on medical image data acquired for this study, in conjunction with extensive data from the open literature. An individual (height, 174.9?cm, weight, 78.6???0.77?kg, and age 26?years) was enrolled in the study for a period of 4?months. 72 scans across three imaging modalities (CT, MRI, and upright MRI) were collected. The whole-body dataset contains 15,622 images. Over 300 individual components representing human anatomy were generated through segmentation. While the enrolled individual served as a template, segmented data were verified against, or augmented with, data from over 75 literature sources on the average morphology of the human body. Non-Uniform Rational...

2011-01-01

225

Designing engineering upgradability into magnetic resonance imagers: Impact on future costs  

Energy Technology Data Exchange (ETDEWEB)

MRI is a powerful diagnostic modality of expanding availability. Equipment and installation amount to nearly $2M per site. An important component of diagnostic efficacy is not just equipment costs but also replacement costs, which for x-ray CT amount to 14-20% of the purchase cost per year; and in the early years of that technology reached 30-50%. The authors show how design choices made during the RandD stages of MRI development have allowed them to improve system performance parameters such as data reconstruction, archiving and display speeds, computational capabilities, operator interfaces, imaging sequence flexibility and signal-to-noise levels. Over the last four years these improvements have been made at a retrofit cost well below the target of 6-7% of the purchase price per year.

1987-02-01

226

Whole-body tumor staging: MRI or FDG-PET/CT?; Ganzkoerpertumorstaging: MRT oder FDG-PET/CT  

Energy Technology Data Exchange (ETDEWEB)

Technical innovations such as the availability of movable patient platforms and the introduction of 32-channel systems have made whole-body MRI for tumor staging feasible. In addition, the development of dual-modality PET/CT systems offers the opportunity to perform anatometabolic tumor staging with whole-body coverage in a single session. Based on an increase in patient survival when applying a stage-adapted therapy in different malignant diseases the relevant question relates to the accuracies of whole-body MRI and whole-body PET/CT for TNM staging. This review article addresses whole-body tumor staging with MRI and FDG-PET/CT with special emphasis on diagnostic accuracies for staging different malignant diseases. (orig.) [German] Technische Neuerungen, wie die Verfuegbarkeit beweglicher Tischaufsaetze oder die Einfuehrung von 32-Kanal-Systemen, haben die Ganzkoerperbildgebung mit der MRT ermoeglicht. Die Entwicklung ...

2004-09-01

227

Ultrasmall superparamagnetic iron oxides (USPIOs): a future alternative magnetic resonance (MR) contrast agent for patients at risk for nephrogenic systemic fibrosis (NSF)?  

UK PubMed Central (United Kingdom)

Gadolinium (Gd) based contrast agents (GBCAs) in magnetic resonance imaging (MRI) are used in daily clinical practice and appear safe in most patients; however, nephrogenic systemic fibrosis...Full Text Available

2009-03-01

228

Quantitative 31P NMR Spectroscopy and 1H MRI Measurements of Bone Mineral and Matrix Density Differentiate Metabolic Bone Diseases in Rat Models  

UK PubMed Central (United Kingdom)

In this study, bone mineral density (BMD) of normal (CON), ovariectomized (OVX) and partially nephrectomized (NFR) rats was measured by 31P NMR spectroscopy; bone matrix density was...Full Text Available

2010-06-01

229

Prognostic value of dynamic MRI in assessing post-traumatic femoral head vascularity  

Energy Technology Data Exchange (ETDEWEB)

The vascular status of femoral heads in the post-traumatic period of intracapsular femoral neck fracture (ICFNF) remains uncertain until the patient actually develops avascular necrosis (AVN). Several methods for predicting the viability of femoral head have been reported, that are not effective or widely used because of unreliability, potential complications, and technical difficulties. The present study involved the use of Dynamic MRI (DMRI) in assessing femoral head vascularity to predict AVN. The role of DMRI was studied prospectively in 30 patients with 31 ICFNF. Fractures were divided in to three types (Type A, B, or C) based on the femoral head vascularity shown by dynamic curve patterns on MRI evaluation. Type A was preserved vascularity, Type B was some decrease in vascularity but still viable while Type C was significantly reduced vascularity. These were followed-up for 6 months to 2 years to observe the final outcome in terms of ...

2009-06-15

230

Morphometric analysis of the temporomandibular joint with MRI in 320 joints; Morphometrische Analyse des Kiefergelenkes anhand von 320 Gelenken mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

Purpose: to compare several morphometric parameters in MRI with the functional status of the articular disc in a large patient group suffering from internal derangement (ID) of the temporomandibular joint (TMJ). Materials and methods: in a retrospective study, 320 analyzable high resolution MRI examinations of the TMJs obtained in a 1.5 T unit were evaluated in 184 patients with clinically suspected ID. The analysis included the anatomical structures and a number of morphometric parameters previously described in the literature. The parameters were compared with the position of the articular disc. Results: the disc position was categorized as ''normal'' (NDP, 21.9%, n = 70), ''anterior displacement with reduction on opening'' (AMR, 51.6%, n = 165) and ''anterior displacement without reduction on opening'' (AOR, 26.6%, n = 85). With ...

2005-02-01

231

A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice  

UK PubMed Central (United Kingdom)

Amyloid plaques are a characteristic feature in Alzheimer’s disease (AD). A novel non-toxic contrast agent is presented, Gd-DTPA-K6Aβ1–30, which is homologous to Aβ,...Full Text Available

2008-06-01

232

MRI of congenital heart disease in childhood; MR-Tomographie kongenitaler Herzvitien im Kindesalter  

Energy Technology Data Exchange (ETDEWEB)

MRI provides a non-invasive diagnostic tool complementing echocardiography on one hand, and showing advantages over echocardiography, on the other hand, especially after corrective procedures. The multiple different MRI sequences need to be adapted to examinations of children and patients with congenital heart disease (CHD), and can be used to detect morphologic changes, blood-flow in the heart and thoracic vessels and diastolic or systolic function of myocardium. Several factors determine the success of the examination of a complex congenital heart disease or a postoperative situs. Pediatric radiologists and radiologists experienced in congenital heart diseases have to work in close cooperation. Echocardiography should be performed before MRI. The results of prior examinations and the clinical history of the patients, including possible palliative or reconstructive operations, must be available before ...

2004-02-01

233

MRI in definition of bleeding source, lesion pattern and therapy in haemarthros of the knee; Die MRT beim Haemarthros des Kniegelenks: Bestimmung von Blutungsursachen, Verletzungsmustern und Therapie  

Energy Technology Data Exchange (ETDEWEB)

Patients with haemarthros of the knee were examined by MRI and arthroscopy to identify the bleeding source and to determine surgical or conservative therapy. A prospective study was performed on 120 patients who underwent MRI and arthroscopy, point lesions and bleeding sources were documented separately on a standardised form. Arthroscopy demonstrated a ruptured anterior cruciate ligament in 86%, meniscal tears in 55%, disruption of collateral ligaments in 17%, osteochondral lesions in 5% and tears of capsule or plicae in 13%. Disruption of cruciate ligaments caused haemorrhage in all but three cases. In contrast, only meniscal tears located very adjacent to the meniscal basement had bled. Those types of osteochondral lesions caused haemorrhage characterised on MRI by destruction of the subchondral plate and overlying cartilage. Severe lesions of the knee were diagnosed by MRI in 71% to 100%, slight ...

1996-09-01

234

Influence of contrast-enhanced CT and MRI with or without SPIO particles on therapy and therapy costs for patients with focal liver disease; Einfluss von biphasischer Spiral-CT, nativer und eisenoxidverstaerkter MRT auf Therapie und Therapiekosten bei Patienten mit fokalen Leberlaesionen  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Evaluation of the diagnostic efficacy and cost-benefit of contrast enhanced CT (CT) and MRI pre- and post-SPIO-particles in focal hepatic disease with consideration of therapeutic outcome. Results: In 34/52 (65.4%) of the cases the correct diagnosis was primarily stated by CT (sensitivity [se.] 85.2%, specificity [sp.] 44.0%). In additional 10/52 of the cases unenhanced MRI (se. 91.4%, sp. 75.0%) enabled correct diagnoses, and in another 6 cases the diagnosis was established only by SPIO-MRI (se. 100%, sp. 86.7%). Considering the possible therapeutic recommendation arising from each modality, CT would have induced needless therapy costs of 191,042 DM, unenhanced MRI of 171,035 DM, and SPIO-MRI of 7,311 DM. In comparison to the real therapy costs of 221,873 DM, this would have corresponded to an unnecessary increase of therapy costs of 86.1%, 77.1%, and 3.3%, respectively. ...

2000-03-01

235

New procedures. Comprehensive staging of lung cancer by MRI; Neue Verfahren. Umfassendes Staging des Lungenkarzinoms mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

Lung cancer staging according to the TNM system is based on morphological assessment of the primary cancer, lymph nodes and metastases. All aspects of this important oncological classification are measurable with MRI. Pulmonary nodules can be detected at the clinically relevant size of 4-5 mm in diameter. The extent of mediastinal, hilar and supraclavicular lymph node affection can be assessed at the same time. The predominant metastatic spread to the adrenal glands and spine can be detected in coronal orientation during dedicated MRI of the lungs. Search focused whole body MRI completes the staging. Various additional MR imaging techniques provide further functional and clinically relevant information during a single examination. In the oncological context the most important techniques are imaging of perfusion and tumor motion. Functional MRI of the lungs complements the pure staging and improves ...

2010-08-15

236

Modern visualization of the liver with MRI - current trends and future perspectives; Moderne Leberbildgebung mit der MRT - aktuelle Trends und Zukunft  

Energy Technology Data Exchange (ETDEWEB)

This contribution provides an overview and imparts basic knowledge on pertinent technical developments in magnetic resonance imaging (MRI) of the liver: 3D sequences, respiratory triggering, parallel imaging, and 3 Tesla (3T). 3D sequences can be used as T1-weighted (T1w) sequences for analyzing dynamics of contrast enhancement or as T2w sequences for MR cholangiography. Consistent improvements in respiratory triggering make it possible to obtain good image quality on T2w scans even in patients unable to hold their breath. Parallel imaging as a universal technique to accelerate image acquisition is particularly appropriate for MRI of the liver, and it has been shown that the reduced acquisition time is not achieved at the expense of image quality. Further progress in MRI of the liver can be expected with use of the 3T systems, but hitherto irrelevant problems must still be solved. Overall the innovations presented here, ...

2004-12-01

237

Magnetic resonance imaging in the evaluation of pneumonia; Nachweis von pneumonischen Infiltraten mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

Magnetic resonance imaging (MRI) of the lung is challenging because of substantial drawbacks. However, lung pathologies that are associated with increased attenuation values in CT enhance visualization in MRI: proton density is increased and tissue-air interfaces, resulting in susceptibility artifacts, are reduced in pneumonia, pneumonitis, edema, and carcinoma. On the other hand, many lung diseases result in shortness of breath, so that patients cannot hold their breath for long periods. Therefore, fast imaging techniques are required which should also allow for high spatial resolution so that small lesions can be detected. Calcifications and air pockets within lesions are not readily recognized with MRI. Thin section CT is standard for the diagnosis of pneumonia. With parallel imaging techniques, MRI examination of the lungs can be performed with short periods of breath holding, which allow for ...

2006-04-15

238

Investigation of respiratory-dependent movements of pulmonary space-occupying lesions with MRI; Untersuchung der atemabhaengigen Bewegungen pulmonaler Raumforderungen mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

Parallel imaging and echo sharing techniques have markedly reduced the acquisition times for MRI of large volumes. Dynamic 2 and 3-dimensional data sets of the chest with high temporal resolution (up to 10 images/s with single slice and 2 volume/s) allow an analysis of respiratory motion of the lungs and tumors. Time-resolved 2D series in preselected planes can be used to observe respiratory motion during free breathing or after respiratory commands, e.g. to exclude chest wall invasion by a tumor or for diagnosing impairment of respiratory mechanics. Time-resolved 3D-series (4D-MRI) allow monitoring of the spatial displacement of the lungs and tumors as a whole volume. Present limitations such as an overestimation of tumor size and an underestimation of displacement due to a limited temporal resolution are expected to be overcome with further technical developments. However, 4D-MRI already appears to be the appropriate tool ...

2009-08-15

240

Combining adjusted and unadjusted findings in mixed research synthesis  

British Library Electronic Table of Contents (United Kingdom)

Abstract Rationale, aims and objectives- Finding ways to incorporate disparate types of evidence into research syntheses has the potential to build a better evidence base for clinical practice and policy. Yet conducting such mixed research synthesis studies is challenging. Researchers have to determine whether and how to use adjusted and unadjusted quantitative findings in combination with each other and with qualitative findings. Methods- Among quantitative findings, adjustment for confounding, either via study design or statistical analysis, can be a considerable source of heterogeneity. Yet there is no consensus about the best way to synthesize findings resulting from different methods for addressing confounding. When synthesizing qualitative and quantitative findings, additional consid...

2011-01-01

241

Aicardi syndrome: a case report and radiologic findings; Sindrome de Aicardi: relato de caso e achados radiologicos  

Energy Technology Data Exchange (ETDEWEB)

The authors report the findings of Aicardi syndrome, a disease of unknown etiology composed of multiple spasms, chorioretinal lacunae and agenesis of the corpus callosum. They present a case of Aicardi syndrome with characteristic clinical presentation and magnetic resonance imaging findings. The disease, despite being considered rare, has characteristic imaging findings. Over the past years magnetic resonance imaging has improved its ability in demonstrating other findings besides agenesis of the corpus callosum, making the radiologist's role very important in the diagnostic suspicion of this disease. (author)

2008-07-01

242

Staging of multiple myeloma with MRI: comparison to MSCT and conventional radiography; Staging des multiplen Myeloms mit der MRT: Vergleich zur MSCT und zur konventionellen Roentgendiagnostik  

Energy Technology Data Exchange (ETDEWEB)

The staging of patients with multiple myeloma demands sensitive imaging methods for the assessment of the skeletal system. MRI allows for direct visualization of the bone marrow which exhibits five different infiltration patterns in multiple myeloma: 1. normal appearance of the bone marrow, 2. focal involvement, 3. homogeneous diffuse infiltration, 4. combined diffuse and focal infiltration, 5. ''salt and pepper'' pattern with inhomogeneous bone marrow signals due to multiple fat islands. The combination of T1w-SE and STIR sequences is best suited for detecting all infiltration patterns and for the differential diagnoses e. g. hemangiomas. With parallel imaging in MRI, acquisition times can be markedly reduced and whole-body screening of the bone marrow can be achieved within 30 min. MRI is superior to radiography for the detection of focal as well as diffuse infiltration. Multidetector ...

2004-09-01

243

Modern imaging methods for diagnostic evaluation of tumors of the oropharynx and the oral cavity; Moderne bildgebende Methoden bei der Diagnostik von Tumoren des Oropharynx und der Mundhoehle  

Energy Technology Data Exchange (ETDEWEB)

Differentiating a benign from a malignant lesion by information such as density data, or signal intensities or echo gradients, is not possible with CT, nor MRI, nor ultrasonography. Only some lesions show characteristic signs. Inflammations cannot be difscriminated from malignant tumors. CTs of small tumors in particular are so poor in contrast that it is much more difficult to detect tumors or discriminate them from other lesions, as compared to MR images or ultrasonographs. CT does not detect surface tumors, but is more sensitive than MRI or US in detecting discrete cortical bone lesions. The same applies to small calcified tumors. MRI however is most sensitive in detecting tumor volumes in the yellow marrow, and is the best modality for evaluation of extraossal extension of tumors. CT yields better results than MRI if applied for simultaneous screening of lymph node metastases in the lower neck. ...

1996-11-01

244

Ultra high field magnetic resonance imaging  

International Nuclear Information System (INIS)

Understanding human brain function, brain development and brain dysfunction is one of the great challenges of the twenty first century. Biomedical imaging has now run up against a number of technical constraints that are exposing limits to its potential. In order to overcome the current limits to high-field magnetic resonance cerebral imaging (MRI) and unleash its fullest potential, the Cea has built NeuroSpin, an ultra-high-field neuroimaging facility at its Saclay centre (in the Essonne). NeuroSpin already boasts three fully operational MRI systems. The first is a 3-tesla high-field system and the second is a very-high-field 7-tesla system, both of which are dedicated to clinical studies and investigations in humans, while the third is an ultra-high-field 17.65-tesla system designed for studies on small animals. In 2011, NeuroSpin will be commissioning an 11.7-tesla ultra-high-field system of unprecedented power that is designed for research ...

245

Role of nuclear medicine and magnetic resonance imaging in cardiac diagnostics; Rolle der nuklearmedizinischen Verfahren und der Magnetresonanztomographie in der kardialen Diagnostik  

Energy Technology Data Exchange (ETDEWEB)

Nuclear medicine and magnetic resonance imaging (MRI) are widely used in cardiac diagnostics. Both techniques have been carefully evaluated and are equivalent for the assessment of regional and global wall motion as well as the evaluation of ejection fraction and cardiac volumes, though MRI is herein currently seen as gold standard. For evaluation of myocardial perfusion, extensive data exist for nuclear imaging, that, next to high diagnostic accuracy for evaluation of coronary artery disease, show incremental prognostic information and allow for independent risk stratification. Because of rapid technical advance, myocardial perfusion imaging has also become feasible with cardiac MRI. Results of recent studies are promising, but the data are few compared to perfusion scintigraphy. For viability assessment in patients with ischemic cardiomyopathy, positron emission tomography (PET) with FDG is currently seen as gold ...

2003-12-01

246

MRI with pathogenic correlation of small renal cell carcinoma  

Energy Technology Data Exchange (ETDEWEB)

MRI, ultrasonography and angiography were performed on 24 cases with small renal cell carcinoma, and data were compared with pathological architecture type. An average diameter of cancer was 20.8 mm (10-30 mm). Each tumor was pathologically classified into four architecture types: alveolar type (15 cases), papillary type (5 cases), tubular type (3 cases) and cystic type (1 case). In comparison with renal cortex alveolar type renal cell carcinoma showed equal or low signal in T1-weighted images and equal or high signal in T2-weighted images. Papillary and tubular types showed high signal in T1-weighted images, and low signal in T2-weighted images. In alveolar type, many cases showed equal echo in ultrasonography and hypervascularity in angiography, and in papillary and tubular types, many cases showed high echo and hypovascularity. There were many cases with papillary type small cell carcinoma which showed low signal intensity of T2-weighted images. This results ...

1999-11-01

247

MR imaging of experimental intramuscular hemorrhage at 0. 02 T; Contrast enhancement with Gd-DOTA  

Energy Technology Data Exchange (ETDEWEB)

Intramuscular hermorrhage was induced by injecting autologous blood into the paraspinal muscle of 8 rabbits. In order to evaluate the time-dependent changes of hemorrhage observed on MRI, the animals were imaged at different stages of blood resolution at 0.02 tesla (T), and control examined with ultrasound using a 7.5 MHz linear transducer. Six inversion recovery sequences (TR=1 000 ms. TE=30 ms, and TI=18, 48, 148, 201, 302, and 398 ms) were used for the invivo calculation of T1 relaxation times. IR 1 000 (398)/30 imaging was performed before and after the Gd-DOTA administration. The hemorrhage was evident on MR images throughout the study, especially on the T2 weighted (SE 1 000/100) images. MRI showed the healing lesion longer than ultrasound. The T1 relaxation time increased during the time of resolution. Lesions on days 4 to 7 enhanced in intensity after the injection of Gd-DOTA. (orig.).

1990-09-01

248

Including the relativistic kinetic energy in a spline-augmented plane-wave band calculation  

International Nuclear Information System (INIS)

The first-order relativistic correction to the kinetic energy of an electron, the mass-velocity term, is not bounded from below. It can, therefore, not be used within a variational framework. To overcome this deficiency we developed a method to include the entire relativistic kinetic energy #sq root#(p"2c"2+m_0"2c"4)-m_0c"2 in a spline-augmented plane-wave band calculation. The first results for silver are quite promising, especially for d and p states: The analysis of the energies of the core states as well as of the valence band structure suggests that the energies of d bands are reproduced within 1 mRy. However, the combination of the relativistic kinetic energy with the Darwin term leads to energies which are too low for s-like valence states by 10 mRy. Therefore, the s and d valence band complex is spread out and the Fermi level is lowered by the same amount as the s states. We expect to overcome these deficiencies in future investigations ...

249

Approximate fuzzy C-means (AFCM) cluster analysis of medical magnetic resonance image (MRI) data  

International Nuclear Information System (INIS)

The authors describe the application of an approximate fuzzy C-means (AFCM) clustering algorithm as a data dimension reduction approach to medical magnetic resonance images (MRI). Image data consisted of one T1-weighted, two T2-weighted, and one T2*-weighted (magnetic susceptibility) image for each cranial study and a matrix of 10 images generated from 10 combinations of TE and TR for each body lymphoma study. All images were obtained with a 1.5 Tesla imaging system (GE Signa). Analyses were performed on over 100 MR image sets with a variety of pathologies. The cluster analysis was operated in an unsupervised mode and computational overhead was minimized by utilizing a table look-up approach without adversely affecting accuracy. Image data were first segmented into 2 coarse clusters, each of which was then subdivided into 16 fine clusters. The final tissue classifications were presented as color-coded anatomically-mapped images and as two and three dimensional ...

250

Post-mortem fetal MRI: What do we learn from it?  

International Nuclear Information System (INIS)

Post-mortem magnetic resonance (MR) imaging is of increasing interest not only as an alternative to autopsy but as a research tool to aid the interpretation and diagnosis of in utero MR images. The information from the post-mortem MR has allowed the development of imaging sequences applicable to in utero imaging and neonatal imaging. It has established brain development during gestation and has provided data on this to which in utero MR can be compared. The detail available from the post-mortem images is such that brain development can be studied in a non-invasive manner, a permanent record on the normal and abnormal areas is available and a greater understanding of developmental abnormalities is possible.

2006-02-01

251

Periosteal Ewing's sarcoma  

International Nuclear Information System (INIS)

Periosteal Ewing's sarcoma is an uncommon, but well documented origin of this malignant condition with radiography signs, different from intramedullary growing tumours. Imaging modalities like CT or MRI supply proof of macroscopically intact endosteal cortical surface and free medullary cavity in long bones affected by this periosteal type of malignancy. Definite confirmation is valid after a careful microscopic investigation of the resected specimen. The prognosis of this type of Ewing's sarcoma may be favourable than that of the central type. Early diagnosis and therapy are thus essential. A clinical survey of six observations is given. (orig.).

252

Magnetic resonance imaging of the pediatric brain  

International Nuclear Information System (INIS)

The atlas presents sequences of MRI sections parallel to the orbito-meatal plane in children from birth through the age of sixteen years. Each child was studied horizontally and sagitally and three-dimensional brain images were reconstructed to facilitate accurate identification of sulci and gyri. The images show crucial aspects of brain development such as the constancy of the brain stem and primitive brain from birth onward; the development of the telencephalon, characterized by deepening of sulci and growth of the cerebral cortex surface; and the different stages of white matter myelinization.

253

MEG studies of human vision: Retinotopic organization of V1  

Energy Technology Data Exchange (ETDEWEB)

A primary goal of noninvasive studies of human vision is to identify and characterize multiple visual areas in the human brain analogous to those identified in studies of nonhuman primates. By combining functional MEG measurements with images of individual anatomy derived from MRI, the authors hope to determine the location and arrangement of multiple visual areas in human cortex and to probe their functional significance. The authors have identified several different visual areas thus far which appear to be topographically organized. This paper focuses on the retinotopic characterization of the primary visual area (V1) in humans.

1993-12-31

254

Inborn Errors of Metabolism Presenting in Childhood  

British Library Electronic Table of Contents (United Kingdom)

Abstract Neurodegenerative and neurometabolic disorders may cause significant morbidity and mortality in children. Imaging is important in early diagnosis of metabolic disorders and in determining the extent of brain injury. Especially after the development of new techniques such as diffusion-weighted magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), neuroimaging plays more important role in the diagnosis and management of these disorders. In these disorders, usually a mutation causes a clinically significant block in one or more metabolic pathways. This blockage usually results in either a deficiency of the product or in an accumulation of substrate with damage induced by either storage or toxicity. The presenting symptoms are usually nonspecific. In some of the ...

2011-01-01

255

First experiences with application of gadolinium-DTPA in infants and small children under two years of age  

International Nuclear Information System (INIS)

The use of Gadolinium-DTPA as a paramagnetic contrast agent in MRI with adults and juveniles concerning brain and spinal cord pathology is well proven since years. In the FRG it is only introduced for children over two years of age. Therefore this report deales with the experience in four infants and small children under the age of two. They all were suffering from neurological tumors and got additional diagnostic information in three cases. Clinical side-effects like urticaria, vomiting or convulsions had not been observed nor had pathologic changes of the biochemical parameters been noticed. (orig./GDG).

256

A delayed case of renal artery pseudoaneurysm presented with gross hematuria and azotemia in solitary kidney following percutaneous nephrostomy: treated by transcatheter coil embolization.  

Science.gov (United States)

Renal arteriovenous fistula or pseudoaneurysms developing after invasive procedures are either asymptomatic or show only transient symptoms. We describe here a case of symptomatic renal artery pseudoaneurysm that presented with gross hematuria and azotemia. The pseudoaneurysm of renal artery was diagnosed by ultrasonography and abdominal magnetic resonance imaging (MRI), and it was successfully treated by percutaneous transcatheter coil embolization. A high index of suspicion is essential for the early diagnosis and treatment of delayed gross hematuria in patients with history of percutaneous nephrostomy. PMID:17180737

2006-12-19

257

3D MRI of the colon: methods and first results of 5 patients; 3D-MRT des Kolons: Methodik und erste Ergebnisse  

Energy Technology Data Exchange (ETDEWEB)

Purpose: `Exoscopic` and endoscopic identification of colorectal pathologies via MRI. Methods: 5 patients (36-88 years), two normal and three with different colorectal pathologies (diverticular disease, polyps and carcinoma of the colon), were examined by MRI after colonoscopy. Subsequent to filling of the colon with a gadolinium-water mixture under MRI-monitoring, 3D-data sets of the colon were acquired in prone and supine positions over a 28 sec breathold interval. Subsequently multiplanar T{sub 1}-weighted 2D-sequences were acquired before and following i.v. administration of Gd-DTPA (0.1 mmol/kg BW). All imaging was performed in the coronal orientation. The 3D-data were interactively analysed based on various displays: Maximum intensity projection (MIP), surface shadowed display (SSD), multiplanar reconstruction (MPR), virtual colonoscopy (VC). Results: All of the colorectal pathologies could be interactively diagnosed ...

1997-09-01

258

Volumetric quantification of brain development using MRI  

International Nuclear Information System (INIS)

We devised a three-dimensional method for estimation of cerebral development and myelination which measures cerebral volume using MRI. Accuracy of the system was estimated using cadaver brains. The mean percentage error in the calculated volumes compared with the real volumes was 2.33 %, range 0.00-5.33 %. We applied the method to the volume of both cerebral hemispheres (CH), basal ganglia, thalamus and internal capsule (BT), and myelinated white matter (WM) in 44 neurologically normal individuals (4 months to 28 years of age), 13 patients with spastic motor disturbances (2-25 years of age), and 9 patients with athetotic motor disturbances (2-23 years of age). In the neurologically normal cases, the volumes of CH, BT and WM increased with age; the volume of MW more slowly than that of CH. In cases with spastic motor disturbances, the volumes of CH, BT and WM were between -1.4 and 3.5 SD, -1.0 and -3.5 SD, and 0.0 and -5.2 SD respectively, of those of ...

259

MRI of normal fetal brain development  

International Nuclear Information System (INIS)

Normal fetal brain maturation can be studied by in vivo magnetic resonance imaging (MRI) from the 18th gestational week (GW) to term, and relies primarily on T2-weighted and diffusion-weighted (DW) sequences. These maturational changes must be interpreted with a knowledge of the histological background and the temporal course of the respective developmental steps. In addition, MR presentation of developing and transient structures must be considered. Signal changes associated with maturational processes can mainly be ascribed to the following changes in tissue composition and organization, which occur at the histological level: (1) a decrease in water content and increasing cell-density can be recognized as a shortening of T1- and T2-relaxation times, leading to increased T1-weighted and decreased T2-weighted intensity, respectively; (2) the arrangement of microanatomical structures to create a symmetrical or asymmetrical environment, leading to structural ...

2006-02-01

260

Injured lateral ankle ligaments: technique and assessment of MRI; Verletzungen des Aussenbandapparates am oberen Sprunggelenk: Untersuchungstechnik und Nachweis mittels MRT  

Energy Technology Data Exchange (ETDEWEB)

56 patients with the clinical diagnosis of sprained ankles were investigated. Evaluation of the anterior (AFTL) and posterior fibulotalar ligament (PFTL) was performed with the foot in dorsiflexion (20 ) and of the fibulo calcanear ligament (FCL) in plantarflexion (45 ). Axial T{sub 1}w-SE and T{sub 2}w-TSE images were obtained. Full-length visualisation of ligmaments in one slice and the extent of injury were evaluated. 12 ankle injuries were confirmed by operation. With MRI full-length visualisation of lateral ankle ligaments was possible in 86%. A partial/complete rupture of the AFTL was noticed in 33/64% and of the FCI in 29/39%, and of the PFTL in 27/5%. Sensitivity/specificity of MRI when compared to surgery was 100/100% for injuries of the AFTL, 64/100% for the FCL, and 33/78% for the PFTL. (orig./MG) [Deutsch] 56 Patienten wurden mit der klinischen Diagnose einer frischen Supinationsverletzung des oberen Sprunggelenkes untersucht. Das ...

1996-03-01

261

Frontopolar and anterior temporal cortex activation in a moral judgment task. Preliminary functional MRI results in normal subjects  

International Nuclear Information System (INIS)

The objective was to study the brain areas which are activated when normal subjects make moral judgments. Ten normal adults underwent BOLD functional magnetic resonance imaging (fMRI) during the auditory presentation of sentences that they were instructed to silently judge as either 'right' or 'wrong'. Half of the sentences had an explicit moral content ('We break the law when necessary'), the other half comprised factual statements devoid of moral connotation ('Stones are made of water'). After scanning, each subject rated the moral content, emotional valence, and judgment difficulty of each sentence on Likert-like scales. To exclude the effect of emotion on the activation results, individual responses were hemo dynamically modeled for event-related f MRI analysis. The general linear model was used to evaluate the brain areas activated by moral judgment. Regions activated during moral judgment included the frontopolar cortex (FPC), medial ...

2001-09-01

262

Diagnosis of plasmocytomas using magnetic resonance imaging  

International Nuclear Information System (INIS)

Background. In multiple myeloma 5 different infiltration patterns can be differentiated: 1. Normal appearance of bone marrow, 2. focal involvement, 3. homogeneous diffuse infiltration, 4. combined diffuse and focal infiltration, 5. 'salt-and pepper' pattern with inhomogeneous bone marrow with interposition of fat islands. Methods. For the fast and total acquisition of all patterns a combination of a T1-weighted spin echo sequence and a fat suppression technique is superior. The focal involvement is clearly demonstrated as areas of high signal intensity on e.g. STIR images. Diffuse involvement can be quantified objectively by calculation of the percentage of signal intensity increase after contrast material injection. MRI is superior to X-ray in focal and diffuse involvement. With ultrafast sequences a 'screening' of the whole red bone marrow as for myeloma infiltration is possible. Prognosis. In prognosis studies diffuse infiltration is inferior to focal ...

2000-08-01

263

Computerized Tomography versus unenhanced and enhanced fast MRI sequences in the study of liver metastases: Qualitative and quantitative analyses  

International Nuclear Information System (INIS)

The authors compared unenhanced and contrast-enhanced fast MRI and Computerized Tomography in the detection of liver metastases. Eleven patients with single or multiple hepatic lesions (42 in all) were submitted to V and magnetic resonance studies; T1- and T2- weighted TSE, T2-weighted TSE with fat suppression, unenhanced breath-hold TFE and early or delayed enhanced breath-hold TFE images were acquired with a 1.5 T superconductive magnet (Philips NT). The quantitative analysis of all magnetic resonance images was performed for contrast/noise ratio (CNR) and number of detected lesions; magnetic resonance and Computerized Tomography images were also compared qualitatively for lesion conspicuity, anatomical structure identification and artifacts. The results were compared with Student's test. Early enhanced breath-hold TFE was statistically superior to T1-weighted TSE (p = .0009), T2-weighted TSE (p = .01) and Computerized Tomography ( p = .0004) for lesion ...

1997-01-01

264

Utility of CT in the diagnosis of psoitis  

International Nuclear Information System (INIS)

A 65-year-old woman who was diagnosed as having psoitis by CT findings, which disclosed non-symmetrical dilation of the psoas muscle and gaseous image. Pus from the psoas muscle seen at surgery corresponded to CT findings. Preoperative CT examination was useful in the establishment of diagnosis. (Namekawa, K.).

1984-01-01

265

High-Speed Ultrahigh-Resolution Optical Coherence Tomography Findings in Chronic Solar Retinopathy  

UK PubMed Central (United Kingdom)

PurposeTo describe ocular findings for a 34-year-old man with chronic solar retinopathy using high-speed ultrahigh-resolution (UHR) optical coherence tomography (OCT).Full Text Available

2008-01-01

266

Endometrial biopsy in Holstein-Friesian dairy cows. III. Bacteriological analysis and correlations with histological findings.  

UK PubMed Central (United Kingdom)

This study examines the results of bacterial culture from 159 endometrial biopsy samples from 97 commercial dairy cows and correlations between bacteriological and histological findings. Bacteria were...Full Text Available

1991-04-01

267

Chorionic villi sampling: cytogenetic and clinical findings in 500 pregnancies.  

UK PubMed Central (United Kingdom)

The cytogenetic findings were analysed in a series of 500 pregnancies in which chorionic villi sampling was performed. In all cases a direct method was used, karyotyping being successful in 481 cases...Full Text Available

1987-08-15

269

The Analytic Methods of Operations Research  

Science.gov (United States)

... of the utility of the terminal outcomes, ... Other stochastic topics, such as random walks, branching ... find special uses, particularly in queueing theory ...

1977-01-01

270

Public Understanding of Cognitive Neuroscience Research Findings: Trying to Peer Beyond Enchanted Glass  

British Library Electronic Table of Contents (United Kingdom)

This article considers the appeal of cognitive neuroscience research to the general public within the context of the deep puzzles involved in using our minds to understand how our minds work. It offers a few promising examples of findings that illuminate the ways of the mind and reveal these workings to be counter-intuitive with our subjective experience. However, this promise is tempered by the powerful role that perception, attention, and cognition play in how we reason about evidence. It argues that the interplay between what we believe about the nature of our minds and what the findings suggest constitutes a primary challenge in encouraging public understanding of cognitive neuroscience findings.

2011-01-01

273

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274

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277

India's tryst with modern astronomy  

CERN Document Server

Sumedh Anathpindika surveys astronomy in India and finds a lively and developing community as well as great public interest.

2011-01-01

278

Early axial spondyloarthritis  

UK PubMed Central (United Kingdom)

Purpose of reviewTo summarize recent advances in the classification of preradiographic axial spondyloarthritis (SpA).Recent findingsFull Text Available

2010-09-01

279

/_// ;_/ AN INTERIM OVERVIEW OF LDEF MATERIALS FINDINGS  

Science.gov (United States)

FEP polyethylene mechanical properties affected by UV. " Siloxane-modified materials resist AO. " Nonsilicone polymers attacked by AO ...

280

X-ray findings in patients with miliary appearance of metallic mercury after suicide attempt  

Energy Technology Data Exchange (ETDEWEB)

This case report evaluates X-ray findings in patients with miliary accumulation of mercury observed after parenteral application of metallic mercury in a suizide attempt. There are certain discrepancies between clinical symptoms and the X-ray findings. A clear demonstration of mercury in coronary blood vessels is possible by fluoroscopy.

1985-03-01

281

Report on the special program 78 satellite geodesy of the technical university of Munich  

Energy Technology Data Exchange (ETDEWEB)

Various topics include: (1) direction finding, (2) range finding, (3) Doppler measurements, (4) construction of a receiver for radio interferometry, (5) mobile laser range finding system, (6) figure-and field parameter determination/geopotential, (7) dynamics of the Earth-Moon system, and (8) kinematics of geodetic point fields.

1981-01-01

282

Imaging findings of central nervous system neuroepithelial cysts  

Energy Technology Data Exchange (ETDEWEB)

Neuroepithelial cysts are rare and mostly asymptomatic cerebrospinal fluid (CSF)-like cysts. We describe herein the imaging findings in five patients with neuroepithelial cysts. Two cases of proven and three of presumed neuroepithelial cysts are presented. Three of five are located in the thalamus, a location which is not characteristic for neuroepithelial cysts. In the case of incidental finding of asymptomatic neuroepithelial cyst, clinical and radiological follow-up is indicated and surgical intervention is not necessarily warranted. (orig.) With 5 figs., 6 refs.

1998-05-01

283

FastBit -- Helps Finding the Proverbial Needle in a Haystack  

Energy Technology Data Exchange (ETDEWEB)

FastBit is a software package designed to meet the searching and filtering needs of data intensive sciences. In these applications, scientists are trying to find nuggets of information from petabytes of raw data. FastBit has been demonstrated to be an order of magnitude faster than comparable technologies. In this brief report, we highlight how we work with a visualization team, a network security team and a DNA sequencing center to find the nuggets in their data.

2006-07-05

284

CT scan findings in cerebral paragonimiasis  

International Nuclear Information System (INIS)

Computed tomography was performed on 5 patients with chronic cerebral paragonimiasis. CT showed solitary or multiple, amorphous, round, or oval calcifications, and ventricular enlargement in all 5 cases. A large low-density area is also found in 4 of the 5 cases. These CT findings are compatible with previously reported findings of simple X-ray films of the skull, pneumoencephalography, and pathological studies. (author).

1982-01-01

285

Enhanced CT in the diagnosis of acute appendicitis to evaluate the severity of disease. Comparison of CT findings and histological diagnosis  

Energy Technology Data Exchange (ETDEWEB)

To assess the potential of CT in evaluating the histological severity of acute appendicitis in comparison with surgical and pathological findings. The CT images of 75 patients with surgically proven appendicitis, including 10 cases of catarrhal, 34 of phlegmonous, and 31 of gangrenous appendicitis, were retrospectively analyzed for the following five CT findings: hazy periappendiceal densities, enlarged appendix, increased enhancement of the appendiceal wall, increased enhancement of the periappendiceal intestinal wall, and deficiency of the appendiceal wall. By comparing all the CT findings and the pathological severity of appendicitis (catarrhal, phlegmonous, and gangrenous), the prevalence of the five CT findings was calculated for each pathological category. Abnormal CT findings were noted in only one case of catarrhal appendicitis. Increased enhancement of the appendiceal wall ...

2001-08-01

286

Comparison of high resolution whole-body MRI using parallel imaging and PET-CT. First experiences with a 32-channel MRI system; Hochaufloesendes Ganzkoerpertumorstaging unter Verwendung paralleler Bildgebung im Vergleich zur PET-CT. Erste Erfahrungen auf einem 32-Kanal-MRT-System  

Energy Technology Data Exchange (ETDEWEB)

To compare the accuracy in the detection and staging of various malignant tumors with high resolution whole-body MRI using parallel imaging with whole-body dual-modality PET-CT. Preliminary results of an interim analysis from a prospective, blinded study are presented, in which 20 patients (mean age 59 years, range 27-77 years) with different oncological diseases underwent whole-body dual modality FDG-PET-CT screening for tumor search or staging in case of confirmed or suspected metastatic disease. All patients also underwent whole-body MRI imaging with the use of parallel imaging (iPAT). High-resolution coronal T1w- and STIR-sequences of 5 body levels with 512 x 512 matrix, axial fast T2w imaging of lung and abdomen (HASTE), contrast-enhanced dynamic and static T1w-sequences of liver, brain, abdomen, and pelvis were performed. Using a 32-channel whole-body MRI scanner (Magnetom Avanto, Siemens Medical Solutions) with a ...

2004-09-01

287

Magnetic resonance imaging. Handbook and atlas; Kernspintomographie. Kompendium und Atlas  

Energy Technology Data Exchange (ETDEWEB)

Magnetic resonance imaging (MRI) as a diagnostic imaging tool relies on the generation of magnetic fields, whereas the computerized tomography (CT) uses X-radiation. The fundamental principle of MRI is the magnetic resonance of paramagnetic atomic nuclei. These nuclei, as e.g. protons (= hydrogen nuclei), are aligned in required orientation by application of a strong magnetic field. Upon simultaneous application of an electromagnetic high-frequency field perpendicular to the axis of the basic magnetic field, and in response to periodical changing of the electromagnetic field at a given frequency, the originally aligned paramagnetic nuclei are forced into a movement similar to that of a ``whipping top``. When the resonance frequency is shut off, the nuclei return to their former, aligned positions, inducing a weak signal in a coil. The series of signals generated by multiple repetition of this process of excitation of nuclei and their return to ...

1999-10-01

288

MRI-based N-staging in esophageal cancer; N-Staging des Oesophaguskarzinoms mittels MRT unter Verwendung von artefaktreduzierenden LOTA-Sequenzen  

Energy Technology Data Exchange (ETDEWEB)

Purpose: For planning the therapeutic strategies and estimating the prognosis in esophageal cancer, N-staging is very important. To date, MRI still is of minor importance as imaging modality of the mediastinum despite promising developments in the past, like ECG-gating or 'averaging' sequences, e.g. LOTA (Long-term averaging), which facilitate mediastinal and thoracic MR-imaging. In a prospective approach, the value of MRI based N-staging was examined with respect to LOTA-sequences. Material and Methods: Within from weeks prior to esophagectomy, standardized MRI of the esophagus was performed in 15 patients (10 squamous-cell-carcinomas and 5 adenocarcinomas) using a 1.5 T whole body scanner. Imaging quality was classified based on depiction of aortic wall or tracheal wall layers. Criteria for malignant infiltration were a diameter of more than 15 mm or a round appearance of a lymph node together with ...

2002-10-01

289

CT and MRI characteristica of tumours of the temporal bone and the cerebello-pontine angle; CT und MRT tumoroeser Veraenderungen des Schlaefenbeins  

Energy Technology Data Exchange (ETDEWEB)

Tumours lesions of the temporal bone and of the cerebello-pontine angle are rare.This tumours can be separated into benign and malignant lesions. In this paper the CT and MRI characteristica of tumours of the temporal bone and the cerebello-pontane angle will be demonstrated. High resolution CT (HRCT) as usually performed in the axial plane are using a high resolution bone window level setting, coronal planes are the reconstructed from the axial data set or will be obtained directly. With the MRI FLAIR sequence in the axial plane the whole brain will be scanned either to depict or exclude a tumour invasion into the brain. After this,T2-weighted fast spin echo sequences or fatsuppressed inversion recovery sequences in high resolution technique in the axial plane will be obtained from the temporal bone and axial T1-weighted spinecho sequences before and after the intravenous application of contrast material will be obtained of this region. ...

2003-03-01

290

MR imaging guidance and monitoring of focal thermotherapies. A review; Steuerung und Monitoring von fokalen Thermotherapien mit der Magnetresonanztomographie. Ein Ueberblick  

Energy Technology Data Exchange (ETDEWEB)

Minimally invasive thermotherapies for focal tissue destruction on the basis of laser-, microwave-, focused ultrasound-, or cryogeninduced changes of tissue temperature represent an alternative to surgical tissue ablation, particularly in the treatment of tumors. The thermotherapy modalities listed necessitate indirect guidance and monitoring, since they often do not lend themselves to immediate visual control. In the brain, in head and neck tumors, in the liver, and in the prostate, MRI reliably and accurately delineates both the positions of interstitial thermotherapy applicators and - in contrast-enhanced, T1-weighted images - the perfusion defects in tissue necrosis induced by thermotherapy. The transfer of results of in-vitro and in-vivo model studies to assess interstitial temperature and lesion development during thermotherapy to the actual treatment of patients, however, is still in an initial phase. Further development of both rapid ...

1998-03-01

291

Inflammatory spine disease as a cause of back pain; Entzuendliche Wirbelsaeulenerkrankungen als Ursache fuer Rueckenschmerzen  

Energy Technology Data Exchange (ETDEWEB)

The aim of this review is to evaluate the role of inflammatory spine disease in patients with chronic back pain. The contribution of imaging modalities for the diagnostic evaluation of back pain is discussed. A systematic literature search based on the classification of seronegative spondyloarthropathies and rheumatoid arthritis was performed. The results of this search and the experiences in a large collective of rheumatological patients are analyzed. The prevalence of rheumatoid arthritis (1-2%) is comparable to that of spondyloarthropathies (1.9%). The etiology of these entities is not fully elucidated. Magnetic resonance imaging is increasingly used for early detection and surveillance of therapy with TNF-{alpha} antagonists. Bone marrow edema, which is only detectable with MRI, represents an early sign of inflammation. Therapy with TNF-{alpha} antagonists is based on clinical and laboratory criteria, and signs of inflammation in MRI. ...

2006-06-15

292

Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI): final 5-year results suggest long-term safety and efficacy  

British Library Electronic Table of Contents (United Kingdom)

Background Limited data is available for investigating the long-term safety and effects of intracoronary progenitor cell therapy in patients with acute myocardial infarction (AMI). Objective To assess the clinical course, NT-proBNP and MRI data as objective markers of cardiac function of the TOPCARE-AMI patients at 5-year follow-up. Design The TOPCARE-AMI trial was the first randomized study investigating the effects of intracoronary infusion of circulating (CPC) or bone marrow-derived progenitor cells (BMC) in 59 patients with successfully reperfused AMI. Results Five-year follow-up data were completed in 55 patients, 3 patients were lost to follow-up. None of the patients showed any signs of intramyocardial calcification or tumors at 5?years. One patient died during the initial hospitali...

2011-01-01

293

The usefulness of CBF brain SPECT in forensic medicine: the civil law codes cases. A description of four cases  

International Nuclear Information System (INIS)

The aim of this report was to assess the usefulness of cerebral blood flow (CBF) scanning utilising the SPECT technique in forensic medicine cases in the area of civil law cases. CBF SPECT scanning was performed in four patients utilising "9"9"mTc-ECD and a triple-head gammacamera. In the analysis both the asymmetry index and cerebellar normalisation were applied. Reference values were obtained by studying 30 healthy volunteers. In those cases CBF SPECT scanning played an important role in forensic argument. It influenced the sentence and the amount of financial compensation. CBF SPECT scanning may provide valuable information in forensic medicine argument in civil law cases, but only when taken together with psychometric tests and other neuroimaging methods (CT, MRI). The value of CBF SPECT scanning alone may be limited in judicial proceedings. (author)

294

The similarity of twin brains  

International Nuclear Information System (INIS)

To test the assumption underlying every morphometric twin study that the brains of monozygotic twins are almost identical. Methods: High resolution MRI of the neurocranium of 26 monozygotic twin pairs were acquired and the volumes of 36 cerebral structures were measured. The same twins served as control group after rear-ranging them into non-related pairs of same sex and matching them for age, body height and body weight. Results: For most of the examined structures the correlations within the twins were significant (R = 0,97-0,59). Except for total forebrain volume the controls showed no significant similarity. Conclusions: For almost every measured cerebral structure the assumption, that significant similarities exist between healthy monozygotic twins is correct. Therefore discordant monozygotic twins represent an excellent sample when investigating cerebral correlates of neurologic and psychiatric disorders. (orig.)

2001-06-01

295

The effects of physical activity, education, and body mass index on the aging brain  

British Library Electronic Table of Contents (United Kingdom)

Abstract Normal human aging is accompanied by progressive brain tissue loss and cognitive decline; however, several factors are thought to influence brain aging. We applied tensor-based morphometry to high-resolution brain MRI scans to determine whether educational level or physical activity was associated with brain tissue volumes in the elderly, particularly in regions susceptible to age-related atrophy. We mapped the 3D profile of brain volume differences in 226 healthy elderly subjects (130F/96M; 77.9 3.6 SD years) from the Cardiovascular Health Study-Cognition Study. Statistical maps revealed the 3D profile of brain regions whose volumes were associated with educational level and physical activity (based on leisure-time energy expenditure). After controlling for age, sex, and physical...

2011-01-01

296

Testosterone reduces amygdalaorbitofrontal cortex coupling  

British Library Electronic Table of Contents (United Kingdom)

Testosterone influences various aspects of affective behavior, which is mediated by different brain regions within the emotion circuitry. Previous neuroimaging studies have demonstrated that testosterone increases neural activity in the amygdala. To investigate whether this could be due to altered regulation of amygdala functioning which is thought to be mediated by the prefrontal cortex, we studied the effects of exogenous testosterone on the interaction between the amygdala and other brain regions. Healthy middle-aged women received a single nasal testosterone dose in a randomized, placebo-controlled, crossover manner, and performed an emotional face matching task while their brain activity was measured with functional MRI. The results show that testosterone rapidly reduced functional co...

2010-01-01

297

Symptomatic hepatic cyst in a child: treatment with single-shot injection of tetracycline hydrochloride  

Energy Technology Data Exchange (ETDEWEB)

The prevalence of hepatic cysts is 0.1% to 0.5% based on autopsy studies, and 2.5% based on US examinations. Percutaneous therapies are a new alternative to surgery. They include simple percutaneous aspiration, catheter drainage alone, and catheter drainage with sclerotherapy. We present an 11-year-old boy admitted to hospital because of abdominal pain. A diagnosis of simple hepatic cyst was made, which was treated with aspiration and tetracycline hydrochloride solution (5%) injection into the cystic cavity. Complete regression was seen on US and MRI examination at 3 months, with total collapse and deflation of the cyst. The cyst regressed totally, leaving a hyperechoic linear scar on US examination at 1 year. On the basis of the clinical and imaging results obtained, percutaneous sclerotherapy of hepatic cysts can be recommended as the treatment of choice and as a valid alternative to laparoscopy in children. (orig.)

2009-10-15

298

Role of death receptor, mitochondrial and endoplasmic reticulum pathways in different stages of degenerative human lumbar disc  

British Library Electronic Table of Contents (United Kingdom)

Intervertebral disc (IVD) cell apoptosis has been suggested to play an important role in promoting the degeneration process. It has been demonstrated that IVD cell apoptosis occurs through either death receptor, mitochondrial or endoplasmic reticulum (ER) pathway. Our study aimed to explore the relationship among these three pathways and grade of IVD degeneration (IVDD). IVDs were collected from patients with lumbar fracture, vertebral tumor, disc herniation or spondylolisthesis. IVDs were distinguished by MRI and histomorphological examination, cell apoptosis was detected by TUNEL staining. Biomarkers of these three apoptosis pathways were detected by RT-PCR and Western blot. Furthermore, the correlation between apoptosis pathways biomarkers and disc pathology were analyzed. Nucleus pulpo...

2011-01-01

299

Observation and control of hepatic specimens with MRI and MRS; Beobachtung und Kontrolle von Fixiervorgaengen in Leberpraeparaten mittels MRT und MRS  

Energy Technology Data Exchange (ETDEWEB)

Purpose: The purpose of this study was to observe the process of fixation in liver specimens non-invasively by means of magnetic resonance. The fixation process of several formaldehyde-containing solutions was monitored with MRI and MRS at two different temperatures. Materials and Methods: Liver specimens were conserved in aqueous fixative solutions containing formaldehyde concentrations of 0.7, 1.8, 4 and 7.2% and at different temperatures of 5 C and 20 C. MRI was performed with T1-, T2- and PD-weighted TSE sequences, a 2D FLASH-sequence with and without magnetization transfer, and a FISP 3D-sequence on a clinical 1.5 Tesla MR whole-body unit, and MRS with {sup 1}H-spectroscopic methods (STEAM-sequence) on a 3 Tesla MR whole-body unit. Results: The diffusion of formaldehyde into the tissue was best identified on PD- and T1-weighted images as a band under the liver surface with increasing thickness, penetrating especially fast during the first ...

2004-04-01

300

Moral Judgments Recruit Domain-General Valuation Mechanisms to Integrate Representations of Probability and Magnitude  

British Library Electronic Table of Contents (United Kingdom)

Summary Many important moral decisions, particularly at the policy level, require the evaluation of choices involving outcomes of variable magnitude and probability. Many economic decisions involve the same problem. It is not known whether and to what extent these structurally isomorphic decisions rely on common neural mechanisms. Subjects undergoing fMRI evaluated the moral acceptability of sacrificing a single life to save a larger group of variable size and probability of dying without action. Paralleling research on economic decision making, the ventromedial prefrontal cortex and ventral striatum were specifically sensitive to the "expected moral value" of actions, i.e., the expected number of lives lost/saved. Likewise, the right anterior insula was specifically sensitive to outcome p...

2010-01-01

301

MRI of liposarcomas. Observations on 28 liposarcomas; Magnetresonanztomographie der Liposarkome. Beobachtungen an 28 Liposarkomen  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Liposarcoma is the most common soft tissue sarcoma in adults. The purpose of the study was to correlate MR imaging features with the four ICD subclasses. Methods: 28 patients with liposarcoma were examined preoperatively on a 1.0 T MRI system, using spin echo sequences, gradient echo imaging and STIR sequences. In all patients, classification of the liposarcomas was made by histologic diagnosis (ICD-10-M-classification). Results: Well differentiated liposarcomas (9 patients) showed a number of MRI features consistent with lipoma (well defined mass high signal intensity (SI) on T{sub 1} images, low signal on T{sub 2} images, no or only little signal increase of tumour tissue after contrast material application, no necrosis). Not well differentiated liposarcomas (myxoid 14 patients, pleomorphic three patients, round cell two patients) revealed the largest part of the mass to be of low SI on T{sub 1}-weighted images. Only scattered fatty ...

1996-08-01

302

MRI evaluation and image processing in gel dosimetry. A study of selected MRI properties and image processing in 3D gel dosimetry  

Energy Technology Data Exchange (ETDEWEB)

Gel dosimetry is a new dosimetry method applied in radiation therapy. Gel dosimeters consist of a radiation sensitive gel, which can integrate absorbed doses from several radiation sources or beams. The dose to the gel can be evaluated by magnetic resonance imaging (MRI), a procedure that is the focus of the present thesis. A robust tool for the evaluation of the nonuniformity in MRI has been developed, the Deviation Image method. Unlike previously presented methods, the Deviation Image method includes all nonuniformity variations across a phantom surface and is insensitive to stochastic noise. Methods for the estimation of stochastic noise were analyzed in terms of sensitivity to nonuniformities. A method that averages the stochastic noise level over five regions over the phantom surface, and a method that assesses the stochastic noise level from the background, were found to be the methods of choice. Pronounced MR image nonuniformity ...

2001-03-01

303

MR-based volumetric analysis of small tumor volumes: accuracy of phantom examinations of simulated eye tumors; Evaluierung der MR-Volumetrie kleiner Volumina am Beispiel von Augentumoren mittels Phantomuntersuchungen  

Energy Technology Data Exchange (ETDEWEB)

Purpose: The determination of tumor volume in ocular tumors is very important for the planning and success of radiation therapy. This study uses an animal model to evaluate the accuracy of MR-based volumetry of ocular tumors. Materials and methods: In a total of 25 porcine eyes obtained from the slaughterhouse, ocular tumors were produced by injecting a mixture of hand creme and Gd-DTPA under ophthalmoscopic guidance. The injected volume varied between 0.05 ml and 2.7 ml. The eyes were examined with a 1.5 Tesla scanner and a 4 cm circular surface coil especially developed for ocular MRI. After data transfer to a separate workstation, volumetric analysis was carried out by three independent radiologists using semiautomated software. The determined volume was compared with the injected volume. Results: Of the 25 prepared porcine eyes, 23 were suitable for volumetric analysis. The injection of the mixture of hand creme and GD-DTPA produced two different types of ...

2003-07-01

304

Evaluation of cost effectiveness for conservative and active management strategies for acoustic neuroma  

British Library Electronic Table of Contents (United Kingdom)

Clin. Otolaryngol. 2009, 34, 438-446. Objective: To determine whether economic costs associated with a conservative management strategy for unilateral acoustic neuroma offer an economic advantage over active management options. Design: Cost and sensitivity analysis on a prospective cohort. Setting: Single centre study within a tertiary referral centre in Toronto, Canada. Participants: 72 patients (32 males, 40 females) aged 36 to 78 years with unilateral acoustic neuroma were assigned initially to a conservative management strategy. Entry criteria were small tumour size (less than 15mm in the cerebellopontine angle), patient preference and/or significant co-morbidity. Interventions: MRI scanning was performed every 6 months for the first year, annually subsequently and then every 2-3 years...

2009-01-01

305

Episodic Future Thinking Reduces Reward Delay Discounting through an Enhancement of Prefrontal-Mediotemporal Interactions  

British Library Electronic Table of Contents (United Kingdom)

Summary Humans discount the value of future rewards over time. Here we show using functional magnetic resonance imaging (fMRI) and neural coupling analyses that episodic future thinking reduces the rate of delay discounting through a modulation of neural decision-making and episodic future thinking networks. In addition to a standard control condition, real subject-specific episodic event cues were presented during a delay discounting task. Spontaneous episodic imagery during cue processing predicted how much subjects changed their preferences toward more future-minded choice behavior. Neural valuation signals in the anterior cingulate cortex and functional coupling of this region with hippocampus and amygdala predicted the degree to which future thinking modulated individual preference fu...

2010-01-01

306

Blood flow quantification with MRI using the phase mapping method. Moeglichkeiten und Grenzen der Blutflussquantifizierung peripherer arterieller Gefaesse mit der MRT unter Anwendung des Phase-Mapping-Verfahrens  

Energy Technology Data Exchange (ETDEWEB)

MRT is able to demonstrate arteries while MR angiography can quantify blood flow by a non-invasive method. In the present paper blood flow measurements were carried out in four selected cases on the basis of phase mapping. In 3 patients with lesions in the pelvis or thigh, angiography was performed in order to localise the stenosis or occlusion and this was followed by qantitative blood flow measurements. The results showed that angiography may not always provide all necessary information concerning a haemodynamically significant stenosis. The method may also be used for quantifying blood flow in the renal arteries and that it has significant advantages over the colour Doppler method. (orig.).

1992-08-01

307

Correctness of multi-detector-row computed tomography for diagnosing mechanical prosthetic heart valve disorders using operative findings as a gold standard  

Energy Technology Data Exchange (ETDEWEB)

The purpose was to compare the findings of multi-detector computed tomography (MDCT) in prosthetic valve disorders using the operative findings as a gold standard. In a 3-year period, we prospectively enrolled 25 patients with 31 prosthetic heart valves. MDCT and transthoracic echocardiography (TTE) were done to evaluate pannus formation, prosthetic valve dysfunction, suture loosening (paravalvular leak) and pseudoaneurysm formation. Patients indicated for surgery received an operation within 1 week. The MDCT findings were compared with the operative findings. One patient with a Bjoerk-Shiley valve could not be evaluated by MDCT due to a severe beam-hardening artifact; thus, the exclusion rate for MDCT was 3.2% (1/31). Prosthetic valve disorders were suspected in 12 patients by either MDCT or TTE. Six patients received an operation that included three redo aortic valve replacements, two redo mitral ...

2009-04-15

308

CT findings of foreign bodies in the chest: a pictorial essay  

Energy Technology Data Exchange (ETDEWEB)

The most common causes of tracheobronchial foreign bodies are peanuts in children, and meat and dentures in adults. The most common causes of esophageal foreign bodies are coins in children and meat in adults. It is passable to diagnose a foreign body by visualization on a chest radiograph, if the foreign bodies are radio opaque. However, if the foreign bodies are radiolucent and the patients do not remember the history of aspiration, it is important to evaluate CT findings for foreign bodies and their complications. We describe the CT findings of various thoracic foreign bodies in children and adults.

2008-05-15

309

Tunnel Sensors Equipment on Environmental Expert  

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... Tunnel Sensors Equipment on Environmental Expert Find and compare a variety of tunnel sensors equipment on the world's largest environmental industry portal. View ...

310

The ultrastructure of conjunctival melanocytic tumors.  

UK PubMed Central (United Kingdom)

The ultrastructure of conjunctival melanocytic lesions in 49 patients was evaluated to find significant differences between benign and malignant cells. The patients studied included 9 with benign epithelial...Full Text Available

1984-01-01

311

The Spectrum of Fundus Autofluorescence Findings in Birdshot Chorioretinopathy  

UK PubMed Central (United Kingdom)

Objective. To describe the diverse patterns observed with the use of autofluorescence fundus photography (FAF) in patients with Birdshot chorioretinopathy (BSCR). Methods....Full Text Available

2009-01-01

312

Tarlov Cyst and Infertility  

UK PubMed Central (United Kingdom)

Background/Objective:Tarlov cysts or spinal perineurial cysts are uncommon lesions. These are mostly incidental findings on magnetic resonance imaging or myelograms. The...Full Text Available

2009-04-01

313

TREE-MENDOUS TIMBER EVALUATION  

Science.gov (United States)

depth timber industry experience with state-of-the-art ... difficult to find high-value pockets of timber (also known as timber stands ) to supply his ...

314

SOFIA - Woody Debris in the Mangrove Forests of South Florida  

Science.gov (United States)

although additional research is needed to corroborate such findings. Key words: Avicennia germinans; disturbance; downed wood; Everglades National Park; Hurricane Andrew;...

2011-09-04

315

Principles of antibody therapy.  

UK PubMed Central (United Kingdom)

The success of monoclonal antibodies in clinical practice is dependent on good design. Finding a suitable target is the most important part as other properties of the antibody can be altered by genetic...Full Text Available

1992-12-05

316

Periodontal disease and spontaneous preterm birth: a case control study  

UK PubMed Central (United Kingdom)

BackgroundSeveral studies have suggested an association between periodontal disease and prematurity but this finding has not been consistently observed.MethodsCase...Full Text Available

317

Optical Coherence Tomography Findings in Idiopathic Macular Holes  

UK PubMed Central (United Kingdom)

Purpose. To describe the characteristics of idiopathic macular holes (MH) on optical coherence tomography (OCT) and correlate OCT with clinical assessment. Design....Full Text Available

2011-01-01

318

Non-opaque soft tissue foreign body: sonographic findings  

UK PubMed Central (United Kingdom)

BackgroundSoft tissue foreign bodies are a common cause of orthopedic consultation in emergency departments. It is difficult to confirm their existence because conventional radiology...Full Text Available

319

Neuroradiologic and Neurophysiologic Findings of Neuralgic Amyotrophy  

UK PubMed Central (United Kingdom)

ObjectiveNeuralgic amyotrophy (NA) is a distinct clinical syndrome that is characterized by the acute onset of shoulder and arm pain, weakness, and sensory loss. The purpose of this...Full Text Available

2010-11-01

320

NASA Orbiter Finds Possible Cave Skylights on Mars - Solar System ...  

Science.gov (United States)

Sep 21, 2007... at night," said Glen Cushing of the U.S. Geological Survey's Astrogeology Team and of Northern Arizona University, Flagstaff, Ariz. ...

321

NAME=\\  

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... Waste Collection Systems Products and Equipment Find and compare a variety of waste collection systems products and equipment on the world's largest environmental industry portal. View product ...

322

NAME=\\  

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...Air Quality Monitoring Networks Products and Equipment Find and compare a variety of air quality monitoring networks products and equipment on the world's largest environmental industry portal. ...

323

Multifunctional aerogel thermal protection systems for hypersonic ...  

Science.gov (United States)

Sep 18, 2007 ... Lightweight structural aerogels would find applications as a component of composite sandwich panels that are both lightweight and insulating ...

324

Mental Health and Traumatic Events  

Science.gov (United States)

News Jobs Grants/Funding Families Prevention Diseases Regulations Preparedness Mental Health and Traumatic Events Find Local Mental Health Services Information for: Parents and...

2011-08-27

325

INVESTIGATION OF THE CORROSION RESISTANCE OF BS ...  

Science.gov (United States)

... 1. IE1O and IM'15 exposed to field corrosion tests at five sites for periods of 12 and 24 months confirm previous findings. ...

1953-12-01

326

Gravity_on_Spinning_Cylinders - NASA Quest  

Science.gov (United States)

You can find a discussion of time travel and Tipler's cylinder at this site: http://www.star-names.freeserve.co.uk/travel.htm ...

327

Gold Mining in the Peruvian Amazon: Global Prices, Deforestation ...  

Science.gov (United States)

Sep 1, 2011 ... We find that since 2003, recent mining deforestation in Madre de Dios, Peru is increasing nonlinearly alongside a constant annual rate of ...

328

Geothermal Energy Equipment in Finland on Environmental Expert  

Wastenet

... Geothermal Energy Equipment in Finland on Environmental Expert Find and compare a variety of geothermal energy equipment in finland on the world's largest environmental ...

329

Geothermal Energy Equipment in Belgium on Environmental Expert  

Wastenet

... Geothermal Energy Equipment in Belgium on Environmental Expert Find and compare a variety of geothermal energy equipment in belgium on the world's largest environmental ...

330

Fuel Cell Technologies Equipment on Environmental Expert  

Wastenet

... Fuel Cell Technologies Equipment on Environmental Expert Find and compare a variety of fuel cell technologies equipment on the world's largest environmental industry portal. View ...

331

Finding the Demons in Our Midst: Utilizing DOD ISR Assets to ...  

Science.gov (United States)

... six major international terrorist attacks are considered ... Tanzania and Kenya), the USS COLE bombing of ... the September 11th terrorist attack on the ...

2002-02-04

332

Female urethral syndrome. A female prostatitis?  

UK PubMed Central (United Kingdom)

The cause of the female urethral syndrome has previously been obscure, as it has been associated by definition with a lack of objective findings but a plethora of subjective complaints of retropubic...Full Text Available

1996-05-01

333

Corrosive Fumes Equipment on Environmental Expert  

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... Corrosive Fumes Equipment on Environmental Expert Find and compare a variety of corrosive fumes equipment on the world's largest environmental industry portal. View ...

334

Corrosion Inhibitors Equipment on Environmental Expert  

Wastenet

... Corrosion Inhibitors Equipment on Environmental Expert Find and compare a variety of corrosion inhibitors equipment on the world's largest environmental industry portal. View ...

335

Comparing healthcare outcomes.  

UK PubMed Central (United Kingdom)

Governments are increasingly concerned to compare the quality and effectiveness of healthcare interventions but find this a complex matter. Crude hospital statistics can be dangerously misleading and...Full Text Available

1994-06-04

336

Biogas Analyzers Equipment on Environmental Expert  

Wastenet

... Biogas Analyzers Equipment on Environmental Expert Find and compare a variety of biogas analyzers equipment on the world's largest environmental industry portal. View ...

337

Advances in Imaging of Vertebral and Spinal Cord Injury  

UK PubMed Central (United Kingdom)

Background/Objectives:Imaging technology is an important part of the diagnosis and management of spinal trauma. Indications and findings in post-traumatic imaging of the vertebral...Full Text Available

2010-04-01

338

Towards quantitative PET/MRI: a review of MR-based attenuation correction techniques  

International Nuclear Information System (INIS)

Positron emission tomography (PET) is a fully quantitative technology for imaging metabolic pathways and dynamic processes in vivo. Attenuation correction of raw PET data is a prerequisite for quantification and is typically based on separate transmission measurements. In PET/CT attenuation correction, however, is performed routinely based on the available CT transmission data. Recently, combined PET/magnetic resonance (MR) has been proposed as a viable alternative to PET/CT. Current concepts of PET/MRI do not include CT-like transmission sources and, therefore, alternative methods of PET attenuation correction must be found. This article reviews existing approaches to MR-based attenuation correction (MR-AC). Most groups have proposed MR-AC algorithms for brain PET studies and more recently also for torso PET/MR imaging. Most MR-AC strategies require the use of complementary MR and transmission images, or morphology templates generated from transmission images. We ...

2009-03-01

339

Stereotactic iridium-192 interstitial brachytherapy for intracranial malignant tumors; Combined with hyperthermia  

Energy Technology Data Exchange (ETDEWEB)

The results of interstitial brachytherapy in 13 patients with malignant brain tumors (malignant glioma 9 cases, metastatic brain tumor 4 cases) were reported. In all patients, Ir-192 thin wires were implanted temporarily in afterloading catheters, which were implanted appropriately by means of MRI or CT guided stereotactic technique. Clinical results on CT scan were as follows: CR (complete response) 1 case, PR (partial response) 6 cases and NC (no change) 6 cases. Even in the NC group, tumor growth was inhibited temporarily. Tumor free intervals were ranged 2-17 months. In early series, the intervals were about 2 months due to incomplete arrangement of radioactive implants. In recent series, prolongation of tumor free interval more than 12 months was achieved due to precise arrangements of implants. MRI guided stereotactic interstitial brachytherapy may provide safe and precise intracranial arrangements of implants, which yield high radiation ...

1990-05-01

340

Stereotactic iridium-192 interstitial brachytherapy for intracranial malignant tumors  

International Nuclear Information System (INIS)

The results of interstitial brachytherapy in 13 patients with malignant brain tumors (malignant glioma 9 cases, metastatic brain tumor 4 cases) were reported. In all patients, Ir-192 thin wires were implanted temporarily in afterloading catheters, which were implanted appropriately by means of MRI or CT guided stereotactic technique. Clinical results on CT scan were as follows: CR (complete response) 1 case, PR (partial response) 6 cases and NC (no change) 6 cases. Even in the NC group, tumor growth was inhibited temporarily. Tumor free intervals were ranged 2-17 months. In early series, the intervals were about 2 months due to incomplete arrangement of radioactive implants. In recent series, prolongation of tumor free interval more than 12 months was achieved due to precise arrangements of implants. MRI guided stereotactic interstitial brachytherapy may provide safe and precise intracranial arrangements of implants, which yield high radiation ...

1990-01-01

341

Radiation therapy for Ewing's sarcoma: Results from Memorial Sloan-Kettering in the modern era  

International Nuclear Information System (INIS)

Purpose: To evaluate the outcomes of patients with Ewing's sarcoma family of tumors (ESFT) treated with modern radiotherapy techniques with MRI along with optimal chemotherapy. Methods and Materials: The records of all 60 patients with ESFT who received radiation to the primary site between 1990 and 2004 were reviewed. All patients received chemotherapy, including vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide. Radiation was used as the sole modality for local control in 31 patients and was given either before (n = 3) or after surgical resection (n = 26) in the remainder. All patients had MRI and CT scan-based treatment planning, and 43% received intensity-modulated radiation therapy. Radiation doses ranged from 30 Gy to 60 Gy (median, 51 Gy), and 35% received hyperfractionated radiotherapy. Results: Median age was 16 years (range, 2-40 years). Because of selection bias for radiotherapy, the majority of primary tumors ...

2006-02-01

342

Outcome of moderately dosed radiosurgery for limited brain metastases. Report of a single-center experience  

International Nuclear Information System (INIS)

Purpose: Efficacy and safety of the own single-center experience with moderately dosed radiosurgery (SRS) for limited (one to four) brain metastases were analyzed and correlated with patient- and treatment-related variables. Patients and Methods: Between 05/1998 and 10/2006, 93 patients received SRS for a total of 142 brain metastases. The median number of brain metastases treated per patient was one (range, one to four). 46 patients (49%) received initial SRS alone, 13 patients (14%) SRS with up-front whole-brain radiotherapy (WBRT), and 34 patients (37%) SRS for recurrent metastases after WBRT. Median dose was 16 Gy (range, 10-20 Gy). Results: Median overall survival (OS) was 7.5 months. The actuarial 6- and 12-month data for OS were 60% and 35%, for local brain control (LBC) 87% and 79%, and for distant brain control (DBC) 48% and 37%, respectively. Only ten of 46 patients (22%) with initial SRS alone ultimately received WBRT. Ten patients suffered from seizures within 3 months ...

2010-02-01

343

Optimizing the fMRI data-processing pipeline using prediction and reproducibility performance metrics: I. A preliminary group analysis.  

Science.gov (United States)

We argue that published results demonstrate that new insights into human brain function may be obscured by poor and/or limited choices in the data-processing pipeline, and review the work on performance metrics for optimizing pipelines: prediction, reproducibility, and related empirical Receiver Operating Characteristic (ROC) curve metrics. Using the NPAIRS split-half resampling framework for estimating prediction/reproducibility metrics (Strother et al., 2002), we illustrate its use by testing the relative importance of selected pipeline components (interpolation, in-plane spatial smoothing, temporal detrending, and between-subject alignment) in a group analysis of BOLD-fMRI scans from 16 subjects performing a block-design, parametric-static-force task. Large-scale brain networks were detected using a multivariate linear discriminant analysis (canonical variates analysis, CVA) that was tuned to fit the data. We found that tuning the CVA model and spatial smoothing ...

2004-01-01

344

Magnetic resonance imaging assessment of brain maturation in preterm neonates with punctate white matter lesions  

International Nuclear Information System (INIS)

Early white matter (WM) injury affects brain maturation in preterm infants as revealed by diffusion tensor imaging and volumetric magnetic resonance (MR) imaging at term postmenstrual age (PMA). The aim of the study was to assess quantitatively brain maturation in preterm infants with and without milder forms of WM damage (punctate WM lesions, PWML) using conventional MRI. Brain development was quantitatively assessed using a previously validated scoring system (total maturation score, TMS) which utilizes four parameters (progressive myelination and cortical infolding, progressive involution of glial cell migration bands and germinal matrix tissue). PWML were defined as foci of increased signal on T1-weighted images and decreased signal on T2-weighted images with no evidence of cystic degeneration. A group of 22 preterm infants with PWML at term PMA (PWML group) were compared with 22 matched controls with a normal MR appearance. The two groups were comparable ...

2007-02-01

345

Long-Term Follow-Up of Percutaneous Balloon Angioplasty in Adult Aortic Coarctation  

International Nuclear Information System (INIS)

Purpose: To assess long-term outcomes following percutaneous transluminal angioplasty (PTA) of congenital aortic coarctation in adults.Methods: Seventeen patients underwent PTA for symptomatic adult coarctation of the aorta. Sixteen patients, with a mean age of 28 years (range 15-60 years), were reviewed at a mean interval after angioplasty of 7.3 years (range 1.5-11 years). Assessment included magnetic resonance imaging (MRI), Doppler echocardiography, and clinical examination. Current clinical measurements were compared with pre- and immediate post-angioplasty measurements.Results: At follow-up 16 patients were alive and well. The patient not included in follow-up had undergone surgical repair and excision of the coarctation segment following PTA. Mean brachial systolic blood pressure for the group decreased from 174 mmHg before angioplasty to 130 mmHg at follow-up (p 0.0001). The mean gradient had fallen significantly from 50.9 to 17.8 at follow-up (p = 0.001). ...

2000-09-01

346

Functional magnetic resonance imaging of the normal and abnormal visual system in early life.  

DEFF Research Database (Denmark)

Functional magnetic resonance imaging (fMRI) in young children may provide information about the development of the visual cortex, and may have predictive value for later visual performance. The purpose of this study was to evaluate the usefulness of fMRI for examining cerebral processing of vision in very young infants and in infants with brain damage. We examined 15 preterm infants, 12 children suspected of having a cerebral visual impairment and 10 children with a normal visual system, all of whom were either spontaneously asleep or sedated with chloral hydrate. Cortical response to stroboscopic light stimulation could be demonstrated in all technically acceptable data sets from children with a post-menstrual age (PMA) of > 41 weeks, but not in younger infants. Children < 60 weeks PMA showed either a blood oxygenation level-dependent (BOLD) signal increase or decrease, while all older children showed a signal decrease. The activated ...

2000-01-01

347

Endoluminal ultrasound applicator with an integrated RF coil for high-resolution magnetic resonance imaging-guided high-intensity contact ultrasound thermotherapy  

International Nuclear Information System (INIS)

High-intensity contact ultrasound (HICU) under MRI guidance may provide minimally invasive treatment of endocavitary digestive tumors in the esophagus, colon or rectum. In this study, a miniature receive-only coil was integrated into an endoscopic ultrasound applicator to offer high-resolution MRI guidance of thermotherapy. A cylindrical plastic support with an incorporated single element flat transducer (9.45 MHz, water cooling tip) was made and equipped with a rectangular RF loop coil surrounding the active element. The integrated coil provided significantly higher sensitivity than a four-element extracorporeal phased array coil, and the standard deviation of the MR thermometry (SDT) improved up to a factor of 7 at 10 mm depth in tissue. High-resolution morphological images (T1w-TFE and IR-T1w-TSE with a voxel size of 0.25 x 0.25 x 3 mm3) and accurate thermometry data (the PRFS method with a voxel size of 0.5 x 0.5 x 5 mm3, 2.2 s/image, 0.3 ...

2008-11-21

348

Digital atlas of fetal brain MRI  

International Nuclear Information System (INIS)

Fetal MRI can be performed in the second and third trimesters. During this time, the fetal brain undergoes profound structural changes. Interpretation of appropriate development might require comparison with normal age-based models. Consultation of a hard-copy atlas is limited by the inability to compare multiple ages simultaneously. To provide images of normal fetal brains from weeks 18 through 37 in a digital format that can be reviewed interactively. This will facilitate recognition of abnormal brain development. T2-W images for the atlas were obtained from fetal MR studies of normal brains scanned for other indications from 2005 to 2007. Images were oriented in standard axial, coronal and sagittal projections, with laterality established by situs. Gestational age was determined by last menstrual period, earliest US measurements and sonogram performed on the same day as the MR. The software program used for viewing the atlas, written in C, permits linked ...

2010-02-01

349

Paraquat-induced pulmonary lesions : HRCT findings in long-term follow-up : a case report  

International Nuclear Information System (INIS)

We illustrate serial HRCT findings over a 16-month period in a 35-year-old woman who had ingested paraquat. Initial areas of ground-glass opacity changed into areas of multiple air cysts on follow up scan obtained five months after ingestion. A further follow-up scan obtained 16 months after ingestion showed improvement, with increased lung volume and normalized lung architecture.

1997-03-01

350

Normal and abnormal fetal brain development during the third trimester as demonstrated by neurosonography  

International Nuclear Information System (INIS)

The multiplanar neurosonographic examination of the fetus enables superb visualization of brain anatomy during pregnancy. The examination may be performed using a transvaginal or a transfundal approach and it is indicated in patients at high risk for CNS anomalies or in those with a suspicious finding during a routine examination. The purpose of this paper is to present a description of the normal brain and of abnormal findings usually diagnosed late in pregnancy, including malformations of cortical development, infratentorial anomalies, and prenatal insults.

2006-02-01

351

Measuring and Explaining Electricity Price Changes in Restructured States  

Energy Technology Data Exchange (ETDEWEB)

An effort to determine the effect of restructuring on prices finds that, on average, prices for industrial customers in restructured states were lower, relative to predicted prices, than prices for industrial customers in non-restructured states. This preliminary analysis also finds that these price changes are explained primarily by high pre-restructuring prices, not whether or not a state restructured. (author)

2006-06-15

352

Geosynchronous orbit magnetopause crossings  

Energy Technology Data Exchange (ETDEWEB)

In this study we extend the analysis of magnetopause crossings observed with Magnetospheric Plasma Analyzer measurements to examine a much larger statistical data set. This study examines 39 maiznetosheath/LLBL intervals from 79 spacecraft-months of observations: these observations were taken from a survey of data from the start of each spacecraft mission and extending through March 1993. In contrast to the previous findings, we find no evidence for a significant dawn/dusk asymmetry in geosynchronous magnetopause crossings.

1994-07-01

353

Finding two-dimensional peaks  

CERN Document Server

Two-dimensional generalization of the original peak finding algorithm suggested earlier is given. The ideology of the algorithm emerged from the well known quantum mechanical tunneling property which enables small bodies to penetrate through narrow potential barriers. We further merge this ``quantum'' ideology with the philosophy of Particle Swarm Optimization to get the global optimization algorithm which can be called Quantum Swarm Optimization. The functionality of the newborn algorithm is tested on some benchmark optimization problems.

2004-01-01

354

Finding the best quadratic approximation of a function  

British Library Electronic Table of Contents (United Kingdom)

This article examines the question of finding the best quadratic function to approximate a given function on an interval. The prototypical function considered is f(x) = ex. Two approaches are considered, one based on Taylor polynomial approximations at various points in the interval under consideration, the other based on the fact that three non-collinear points determine a unique quadratic function. Three different techniques for measuring the error in the approximations are considered.

2011-01-01

355

Computed tomography in migratory disorders of human brain development  

International Nuclear Information System (INIS)

Computed tomographic findings in developmental brain anomalies are more easily classified when the system used is based on embryogenesis related to morphology. Analysis of computed tomographic findings in a series of 154 patients with brain anomalies (Chiari malformation not included) revealed that specific examples of abnormalities occurring in major stages of brain development may be recognized by computed tomography. This paper deals with a group of patients with abnormalities that reflect a disturbance in neuronal migration. (orig.).

356

Action plan for the Tiger Team assessment report  

Energy Technology Data Exchange (ETDEWEB)

This document contains responses and planned actions that address the findings of the Tiger Team Assessment of Brookhaven National Laboratory, June 1990. In addition, the document contains descriptions of the management and organizational structure to be used in conducting planned actions, root causes for the problems identified in the findings, responses, planned actions, schedules and milestones for completing planned actions, and, where known, costs associated with planned actions.

1990-08-30

357

A guide to choosing a school : Directgov - Parents  

Wastenet

...authority's and schools' prospectuses Finding a school to suit your child School performance: test results and Ofsted reports Applying for a school place Once you ... Finding a school to suit your child School performance: test results and Ofsted reports Applying for a school place: admissions criteria Apply for ...

358

Dura thickening adjacent to intracranial tumors on MRI. Histologically correlation; Duraverdickung am Rand intrakranieller, duranaher Raumforderungen in der MRT. Histologische Korrelation  

Energy Technology Data Exchange (ETDEWEB)

Purpose: With intracranial tumors a flat, contrast-enhancing, probably dural structure adjacent to the tumor can occasionally be observed on gadolinium-DTPA enhanced MR images. Therefore we have attempted to evaluate a tumor infiltration of this enthancement on MRI. Material and Methods: This study included 50 patients. 19 patients had a dural thickening at the tumor base (13 meningiomas and 6 metastases), while 31 patients did not (12 meningiomas and 19 metastases). Studies included plane T{sub 2}-weighted spin echo (SE) images as well as T{sub 1}-weighted axial, coronal, or sagittal plains with and without contrast agent. Histopathological examinations, were done on the tumor base adjacent to the dura mater. Results: 7 of 12 meningiomas showed a meningeal thickening on MRI with histopathologically proven tumor infiltration as did also 5 of 6 metastases. But 3 of 12 meningiomas and 15 of 19 metastases without dural thickening at the tumor base ...

1997-11-01

359

Diagnosis of plasmocytomas using magnetic resonance imaging; Diagnostik des Plasmozytoms mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

Background. In multiple myeloma 5 different infiltration patterns can be differentiated: 1. Normal appearance of bone marrow, 2. focal involvement, 3. homogeneous diffuse infiltration, 4. combined diffuse and focal infiltration, 5. 'salt-and pepper' pattern with inhomogeneous bone marrow with interposition of fat islands. Methods. For the fast and total acquisition of all patterns a combination of a T1-weighted spin echo sequence and a fat suppression technique is superior. The focal involvement is clearly demonstrated as areas of high signal intensity on e.g. STIR images. Diffuse involvement can be quantified objectively by calculation of the percentage of signal intensity increase after contrast material injection. MRI is superior to X-ray in focal and diffuse involvement. With ultrafast sequences a 'screening' of the whole red bone marrow as for myeloma infiltration is possible. Prognosis. In prognosis studies diffuse ...

2000-08-01

360

Computerized tomography and head growth curve infantile macrocephaly with normal psychomotor development  

Energy Technology Data Exchange (ETDEWEB)

Macrocephaly was defined as a head measuring larger than 98th percentile. We have evaluated CT findings and head growth curves in 25 infants with large heads. Ten (40%) of 25 infants with large heads were normal developmentally and neurologically. Five (20%) of those were mentally retarded. The other 10 infants (40%) included hydrocephalus (4 cases), malformation syndrome (3 cases), brain tumor (1 case), metabolic disorder (1 case) and degenerative disorder (1 case). Their head growth curves were typed as (I), (II) and (III): Type (I) (excessive head growth curve to 2 SDs above normal); Type (II) (head growth curve gradually approached to 2 SDs above normal); Type (III) (head growth curve parallel to 2 SDs above normal). Ten of macrocephaly with normal psychomotor development were studied clinically and radiologically in details. They were all male. CT pictures of those showed normal or various abnormal findings: ventricular dilatations, wide ...

1982-01-01

361

The use of healthy volunteers instead of patients to inform drug dosing studies: a [11C]raclopride PET study  

British Library Electronic Table of Contents (United Kingdom)

Rationale Receptor occupancy study has been performed to evaluate pharmacokinetic profiles in new antipsychotic drug development. While these findings highlight the value of positron emission tomography (PET) for dose-finding study, what is unclear is if it is necessary to conduct these studies in patients with schizophrenia or whether studies in healthy volunteers are adequate. Objectives To determine if it is necessary to conduct dopamine receptor occupancy studies in patients with schizophrenia or whether studies in healthy volunteers are adequate for dose-finding study, we compared the concentration?occupancy relationship in terms of EC50 between patients and healthy volunteers. Methods Ten healthy volunteers and eight patients with schizophrenia participated in the study. We measured ...

2011-01-01

362

The chance finding of an aneurysm of the right sinus of Valsalva in an 11-year-old child with a ventricular septal defect and a pericardial effusion  

British Library Electronic Table of Contents (United Kingdom)

Ventricular septal defects can occur as part of other congenital cardiac malformations or as an isolated finding. Aneurysms of the sinus of Valsalva are rare, most commonly involving the right or noncoronary sinuses. They can be congenital or acquired through infection, trauma, or degenerative diseases. They frequently co-exist with ventricular septal defects, aortic valve dysfunction, or other cardiac abnormalities. More commonly, sinus of Valsalva aneurysms are diagnosed after the clinical sequelae of rupture. Several etiologic factors may lead to the development of pathologic pericardial effusion and the detection of pericardial effusion was one of the first applications of echocardiography to gain widespread acceptance. We present a case of a chance finding of an aneurysm of the right ...

2011-01-01

363

Stellar Pollution in the Solar Neighborhood  

CERN Document Server

We study spectroscopically determined iron abundances of 642 solar-type stars to search for the signature of accreted iron-rich material. We find that the metallicity [Fe/H] of a subset of 466 main sequence stars, when plotted as a function of stellar mass, mimics the pattern seen in lithium abundances in open clusters. Using Monte Carlo models we find that, on average, these stars have accreted about 0.4 Earth masses of iron while on the main sequence. A much smaller sample of 19 stars in the Hertzsprung gap, which are slightly evolved and whose convection zones are significantly more massive, have lower average [Fe/H], and their metallicity shows no clear variation with stellar mass. These findings suggest that terrestrial-type material is common around solar type stars.

2000-01-01

364

Resonances in gravitational scenario given by deformed branes  

Science.gov (United States)

In this work we examine a five-dimensional brane-world model with brane structure driven by a real scalar field. From the deformation of a kink-like defect we find a new class of brane solutions containing internal structures which have implications for the way the background space-time is constructed and the way its curvature behaves. Initially, for spin 0 scalar field, we find a zero mode which can be localized on the deformed brane. However, this result can change by the gravitational interaction with the brane internal structure. Analyzing the massive modes of the scalar field, using two different methods, we find resonance structures similar to those found in the study of gravity localization. The main objective here is to observe the contributions of the deformation procedure to the resonances and to the well known field localization methods.

2011-08-01

365

Paroxysmal nocturnal hemoglobinuria: a case report of MR, CT findings  

Energy Technology Data Exchange (ETDEWEB)

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease involving multiple hematopoietic cell lines. Characteristics of PNH are intrinsic hemolytic anemia, iron deficiency anemia and venous thrombosis. We report a case of PNH with characterostoc MR and CT findings. The signal intensity of renal cortex was lower than that of medulla on both T1-and T2-weighted MR imaging. On T2 weighted MR images, the liver showed very low signal intensity but the signal intensity of the spleen was normal. On precontrast CT the attenuation of renal cortex was higher than that of renal medulla and the attenuation of liver was higher than that of the spleen. These findings of MR imaging and CT were the result from the deposition of hemosiderin in the cells of proximal convoluted tubules and transfusional hemosiderosis of liver.

1995-10-15

366

Numerical and semi-analytic core mass distributions in supersonic isothermal turbulence  

CERN Document Server

We investigate the influence of the turbulence forcing on the mass distributions of gravitationally unstable cores by postprocessing data from simulations of non-selfgravitating isothermal supersonic turbulence with varying resolution. In one set of simulations solenoidal forcing is applied, while the second set uses purely compressive forcing to excite turbulent motions. From the resulting density field, we compute the mass distribution of gravitationally unstable cores by means of a clump-finding algorithm. Using the time-averaged probability density functions of the mass density, semi-analytic mass distributions are calculated from analytical theories. We apply stability criteria that are based on the Bonnor-Ebert mass resulting from the thermal pressure and from the sum of thermal and turbulent pressure. Although there are uncertainties in the application of the clump-finding algorithm, we find systematic differences in ...

2010-01-01

367

Libraries and return on investment (ROI): a meta-analysis  

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to show that the need to communicate the value of libraries is growing, and especially now during the global financial crisis. As a response library valuation research is expanding and there is now a need for a status report. Design/methodology/approach - The library valuation field is developing towards generating a critical mass of empirical studies. The focus of the meta-analytical review is on the subgroup that reports a return on investment (ROI) or a cost-benefit ratio. Meta-analysis is a quantitative analysis of findings of previous studies, conducted to infer general findings and lessons from prior empirical research. The dataset is 38 library valuation studies reporting a return on investment figure or cost-benefit ratio. Findings - Of the 38...

2009-01-01

368

Intracranial Dural Metastasis of Ewing's Sarcoma: a Case Report  

International Nuclear Information System (INIS)

Ewing's sarcoma is a malignant bone tumor that can occur anywhere in the body, but it is most commonly observed in the long bones of the arms and legs, the pelvis and in the chest. The predominant sites of metastasis include the lung (38%), bone (including the spine; 31%), and the bone marrow (11%). Metastasis of Ewing's sarcoma to the central nervous system (CNS) is relatively rare, and most of the previous reports have demonstrated involvement of the bony calvarium or brain parenchyma. We describe here the imaging findings of dural metastasis of Ewing's sarcoma, and these imaging findings have not been previously reported on in the medical literature. In conclusion, dural metastasis of Ewing's sarcoma is very rare and its imaging characteristics are similar to those of a primary tumor, which mimic the findings of a schwannoma or meningioma. Despite its rarity, secondary Ewing's sarcoma may be included in the differential ...

2008-02-01

369

Importance of preoperative imaging with 64-row three-dimensional multidetector computed tomography for safer video-assisted thoracic surgery in lung cancer  

British Library Electronic Table of Contents (United Kingdom)

Purpose Video-assisted thoracic surgery (VATS) has recently been adopted for complicated anatomical lung resections. During these thoracoscopic procedures, surgeons view the operative field on a two-dimensional (2-D) video monitor and cannot palpate the organ directly, thus frequently encountering anatomical difficulties. This study aimed to estimate the usefulness of preoperative three-dimensional (3-D) imaging of thoracic organs. Methods We compared the preoperative 64-row three-dimensional multidetector computed tomography (3DMDCT) findings of lung cancer-affected thoracic organs to the operative findings. Results In comparison to the operative findings, the branches of pulmonary arteries, veins, and bronchi were well defined in the 3D-MDCT images of 27 patients. Conclusion 3D-MDCT imag...

2009-01-01

370

IT IS THE EYES AND NOT THE SIZE THAT MATTER  

British Library Electronic Table of Contents (United Kingdom)

The number of immigrants to Western Europe has been increasing, with immigration the subject of much controversy in contemporary Europe. In this article, we investigate the relationship between the size of the immigrant population, how natives perceive this size, and their anti-immigrant attitudes. We use data from the 2002/2003 European Social Survey covering 17 Western European countries, and we find that as a rule Western Europeans think that the immigrant population in their country is much larger than it actually is. The perceived size of an immigrant population has an impact on anti-immigrant prejudices, but the real size does not. Like many authors before us, we find that education reduces prejudice. However, we also find that around 10 percent of the total effect of education is a ...

2011-01-01

371

Dynamical evolution of a scalar field coupling to Einstein's tensor in the Reissner-Nordstroem black hole spacetime  

International Nuclear Information System (INIS)

We study the dynamical evolution of a scalar field coupling to Einstein's tensor in the background of a Reissner-Nordstroem black hole. Our results show that the coupling constant #eta# imprints in the wave dynamics of a scalar perturbation. In the weak coupling, we find that with the increase of the coupling constant #eta# the real parts of the fundamental quasinormal frequencies decrease and the absolute values of imaginary parts increase for fixed charge q and multipole number l. In the strong coupling, we find that for l#not =#0 the instability occurs when #eta# is larger than a certain threshold value #eta#_c which deceases with the multipole number l and charge q. However, for the lowest l=0, we find that there does not exist such a threshold value and the scalar field always decays for arbitrary coupling constant.

2010-10-15

372

Detecting retroviral sequences in chronic fatigue syndrome.  

Science.gov (United States)

XMRV or xenotropic murine leukemia virus-related retrovirus, a recently discovered retrovirus, has been linked to both prostate cancer and chronic fatigue syndrome (CFS). Recently, the teams of Drs. Shyh-Ching Lo and Harvey Alter discovered the presence of sequences closely related to XMRV in the blood of 86.5% of patients with CFS [1]. These findings are important because since the initial discovery of XMRV in CFS, several studies have failed to find XMRV in specimens collected from CFS patients. While the current study also did not find XMRV in CFS, Lo et al. did detect sequences that belong to polytropic mouse endogenous retroviruses (PMV), which share considerable similarity with XMRV. Criteria for future studies that will help bring greater clarity to the issue of retroviral sequences in CFS are proposed below. PMID:21994623

2010-11-03

373

Care programmes and integrated care pathways  

British Library Electronic Table of Contents (United Kingdom)

Purpose - The article discusses how care programmes and integrated care pathways can be linked, finding ways to improve healthcare process professional and logistical quality from a supply chain and a network point-of-view. Design/methodology/approach - The authors argue that owing to cost containment goals and increasing healthcare demand, healthcare services systems are challenged to improve service quality, whilst at the same time finding ways to improve delivery processes. It explores if the combination of two instruments, care programmes and integrated care pathways, can meet both goals. This combination is illustrated by an example from the Institute of Mental Health Care Eindhoven en de Kempen. Findings - Analysis suggests that care programmes can be combined with integrated care pa...

2008-01-01

374

CT findings of malignant lymphoma of the anterior mediastinum. Differentiation from invasive thymoma  

Energy Technology Data Exchange (ETDEWEB)

CT findings were compared retrospectively between 9 cases with malignant lymphoma of the anterior mediastinum and 8 cases with invasive thymoma. CT findings of malignant lymphoma were as follows: (1) The majority of the tumors were bilateral and extended beyond the anterior mediastinum to the other mediastinum compartments. (2) Their margin was either smooth or lobulated. (3) Their density was either homogeneous or heterogeneous. In the case with heterogeneous density, ring, triangle and/or band-like low density areas, just like interspace of fused lymph nodes, were demonstrated. Calcification or cysts could not be shown. (4) Patent inherent vessels without deviation were occasionally demonstrated running through the tumors. (5) The tumors faced and contacted widely to anterior chest wall and often pressed the lung laterally at the anterior parietomediastinal pleural reflection. (6) Pleural implants were not demonstrated. (author).

1989-04-01

375

CF findings of bowel infarction in 56 surgical patients, 5 of whom with reversible ischemia  

International Nuclear Information System (INIS)

Bowel infarction is a rare and typical condition of the elderly; despite improvements in diagnostic imaging and vascular surgery, bowel infarction remains a major cause of acute abdomen, with mortality rates ranging 70-80%. Diagnosis on often late because clinical sings, laboratory data and radiologic findings are a specific. The authors investigated radiographic and particular CT patterns of intestinal infraction in 56 patients submitted to surgery within 12 hours of admission. We also report the CT findings of 5 of these patients who had reversible mesenteric ischemia. CT is more sensitive than radiography and does not exhibit the limitations of angiography (i.e., invasiveness, radiation exposure an complex organization. Therefore CT can presently be considered the method of choice in patients with suspected bowel infarction.

1999-04-01

376

Analysis of cerebrospinal fluid from chronic fatigue syndrome patients for multiple human ubiquitous viruses and xenotropic murine leukemia-related virus  

British Library Electronic Table of Contents (United Kingdom)

Abstract Recent reports showed many patients with chronic fatigue syndrome (CFS) harbor a retrovirus, xenotropic murine leukemia-related virus (XMRV), in blood; other studies could not replicate this finding. A useful next step would be to examine cerebrospinal fluid, because in some patients CFS is thought to be a brain disorder. Finding a microbe in the central nervous system would have greater significance than in blood because of the integrity of the blood-brain barrier. We examined cerebrospinal fluid from 43 CFS patients using polymerase chain reaction techniques, but did not find XMRV or multiple other common viruses, suggesting that exploration of other causes or pathogenetic mechanisms is warranted. Ann Neurol 2011;

2011-01-01

377

An immunohistochemical study in cases with usual and unusual clinicopathological findings of canine visceral leishmaniosis  

British Library Electronic Table of Contents (United Kingdom)

The present study describes pathologic findings and immunohistochemical diagnosis of canine visceral leishmaniasis (CVL) in 22 dogs who died naturally in the Aegean region of Turkey. At necropsy, lymphadenomegaly, hepatosplenomegaly, hepatic, and nephrosclerotic lesions were conspicuous. Histopathologically, chronic inflammatory reactions of the spleen, lymph nodes, bone marrow, liver, and skin were marked findings. Cytological and histological examinations showed macrophages loaded with Leishmania amastigotes in these organs. Immunohistochemistry revealed that immunolabeling of amastigotes and/or parasite antigen, especially in the lymph nodes, spleen, bone marrow, liver, and skin, and occasionally, in the kidneys, intestines and lungs. Our laboratory results showed that immunohistochemis...

2011-01-01

378

Waterjet resection of brain metastases - first clinical results with 10 patients.  

Science.gov (United States)

The waterjet technique enables precise tissue dissection without thermal damage and with preservation of vessels in general surgery. In neurosurgery, these qualities could help to avoid damage of intact brain parenchyma in tumour resections. The present study reports our first results with this technique in brain metastases. Ten patients with intracranial metastases underwent surgery with the aid of the waterjet. Resection was performed in combination with conventional neurosurgical methods. The follow-up consisted of neurological examination and MRI studies. Intraoperatively, the device was easy to handle. No complications due to the device were observed. Vessels were preserved at pressures below 20 bars. Six of the tumours consisted of soft tissue which was poorly demarcated from the surrounding brain. In these tumours, the waterjet was very helpful. It enabled tumour debulking by aspiration and - more important - precise separation of tumour and brain ...

2003-05-01

379

Solid-pseudopapillary tumor of the pancreas in a 13-year-old girl - case report  

International Nuclear Information System (INIS)

The solid-pseudopapillary tumor (SPT) of the pancreas is a rare type of exocrine pancreatic neoplasm. SPT predominantly affects young women and female children, and is usually discovered incidentally. This tumor is generally benign with a low incidence of malignancy. A 13-year-old girl was admitted to the hospital with a few weeks' history of mild abdominal pain and jaundice. On physical examination, there was no palpable mass. The laboratory tests showed increased SR, CRP, high bilirubin, amylase and lipase serum levels. Ultrasound imaging revealed a solid lesion in the region of the pancreatic head. On MRI, precise tumor localization in the head of the pancreas with pancreatic duct dilatation and compression of the common bile duct were visualized. Pancreaticoduodenectomy and cholecystectomy was performed with good clinical outcome. Microscopic and immunohistochemical studies indicated that tumor cells were typical of SPT without any signs of malignancy. After ...

380

Magnetic resonance imaging in patients with heart valve prostheses  

International Nuclear Information System (INIS)

Artifical valve prostheses are often regarded as a contraindication for magnetic resonance imaging (MRI), although preliminary in vitro studies suggested, that patients with these metallic implants might safely undergo MR examination. This study reports on the experience with a group of 89 patients with 100 heart valve prostheses who were examined by spin-echo MR and gradient-echo MR. MR examination was performed in all patients without complications. The spin-echo sequence showed advantages in the depiction of anatomical structures like paravalvular abcesses. Anatomical structures adjacent to the artificial valve were clearly visivle and the metal components of the valves showes no or only small artifacts. Artifacts were accentuated when using gradient-echo sequences. Gradient-echo sequences provided valuable information regarding the presence of valvular insufficiency. Physiological valvular regurgitation was easy to differentiate from pathological paravalvular ...

381

MRI with SPIR sequences of optic nerve lesions; Utilita' delle sequenze 'Selective Partial Inversion Recover' (SPIR) nelle mallattie del nervo ottico  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the yield of SPIR sequences with fat suppression in the diagnosis of optic nerve lesions. T1 and T2 weighted fat suppressed SPIR imaging of the optic nerve improves anatomical definition, lesion detection and characterization in optic nerve conditions. [Italian] L'articolo analizza i vantaggi ricavabili dall'utilizzazione delle sequenze SPIR nella documentazione del decorso del nervo ottico e delle sue alterazioni nei pazienti con sospetto clinico e strumentale di malattia retrobulbare. L'utilizzo delle sequenze SPIR consente ottimale visualizzazione del nervo ottico e delle sue eventuali alterazioni senza gli artefatti che limitavano la qualita' delle immagini nelle prime sequenze RM con soppressione del segnale del grasso.

1999-04-01

382

Handbook on diagnostic radiology. Muscels and skeleton 2; Handbuch diagnostische Radiologie. Muskuloskelettales System 2  

Energy Technology Data Exchange (ETDEWEB)

The second volume contains a comprehensive presentation of inflammatory bone diseases, including seldom primary chronic osteomyelitis and morbus Paget. Substantial chapters on bone tumors and tumor-like lesions of bone joints are covering the state-of-the-art of diagnostic techniques of these seldom but important diseases. Besides the importance of projection radiography the contribution of MRI within differential diagnosis und staging of these diseases is emphasized. [German] Der zweite Band des Muskuloskelettalen Systems befasst sich mit der umfassenden Darstellung zur Diagnostik entzuendlicher Knochenerkrankungen und beinhaltet neben den klassischen infektioesen auch die seltenen, primaer chronischen Osteomyelitiden und den Morbus Paget. Umfangreiche Kapitel ueber die Knochentumoren und tumoraehnlichen Laesionen der Gelenke stellen in modernster Weise den aktuellen Stand des Wissens und der Diagnostik dieser seltenen, aber aus differenzialdiagnostischer Sicht ...

2005-07-01

383

Gd-25 DTPA-MAb, a potential NMR contrast agent for MRI in the xenografted nude mouse: preliminary studies  

Energy Technology Data Exchange (ETDEWEB)

Monoclonal antibodies (MAbs) 19-9 and 73-3 specific for human colon adenocarcinoma were labelled with a high number of gadolinium atoms. Twenty five DTPA were chelated per MAb, with only slight loss of immunoreactivity. The NMR contrast agent Gd-25 DTPA-MAb 19-9 or 73-3 ((Gd) 17 mumole/kg, (MAb) 60 microM) was injected into nude mice bearing human colon adenocarcinoma (SW948). Tumors were removed 24 hr after injection and T1 was measured in vitro. T1 relaxation time varied according to MAb specificity against tumour targets; T1 decreased 20% for MAb 19-9 and MAb 73-3 with SW948 tumor. Imaging was performed with this model. Very good contrast was obtained 24 hr after Gd-25 DTPA-MAb injection.

1988-01-01

384

Fast quantitative diffusion-tensor imaging of cerebral white matter from the neonatal period to adolescence  

International Nuclear Information System (INIS)

We investigated the isotropic diffusion coefficient (D') and fractional anisotropy (FA) in white matter (WM) during brain development, using an optimised diffusion-tensor imaging (DTI) method with whole brain coverage in a clinically acceptable time. We images 52 children with no evident neurological abnormality (30 boys, 22 girls aged 1 day-16 years) using high-angle DTI with optimised temporal gradient performance. D' and FA were calculated in 10 regions of interest in white matter. We saw that the age-related reduction in D' and increase in FA follow a mono- or biexponential model in white matter, probably depending on the compactness and myelination rate of the fibre tracts. In contrast to other areas, in which adult values were reached during the third year, there is a trend to continuous increase in FA in all deep white-matter areas, suggesting continuing maturation and organisation of deep tracts not detected on conventional MRI. (orig.)

2004-04-01

385

Evaluation of left ventricular volumes in patients with congenital heart disease and abnormal left ventricular geometry. Comparison of MRI and transthoraic 3-dimensional echocardiography; Vergleich der transthorakalen 3D-Echokardiographie mit der MRT zur Bestimmung linksventrikulaerer Volumina bei Patienten mit pathologischer Ventrikelgeometrie aufgrund angeborener Herzfehler  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To assess the new method of 3-dimensional echocardiography in comparison to the 'gold standard' MRI as to its ability to calculate left ventricular volumes in patients with congenital heart disease. Materials and methods: Eighteen patients between the ages of 3.9 to 37.3 years (mean: 12.8{+-}9.7) with a geometrically abnormal left ventricle were examined using a 1.5 T scanner with a fast gradient-echo sequence (TR=14 ms, TE=2.6-2.9 ms, FOV=300-400 mm, flip angle=20 , matrix=128:256, slice thickness=5 mm, retrospective gating) in multislice-multiphase technique. Transthoracic 3D-echocardiography was performed with a 3.5 MHz transducer and a Tomtec {sup trademark} (Munich, Germany) system for 3D reconstruction. Results: Volume calculation was possible in all patients with 3D-echocardiography, but the muscle mass calculation only succeeded in 11 to 18 patients (61%) due to inadequate visualization of the entire myocardium. Comparing ...

2003-07-01

386

Diagnostic features of intrahepatic cholangiocarcinoma according to the gross type classification  

International Nuclear Information System (INIS)

Forty resected cases of intrahepatic cholangiocarcinoma were classified into four types according to the gross appearance; type I: mass forming type (n=8), type II: mass forming with periductal infiltrating type (n=20), type III: periductal infiltrating type (n=9) and type IV: intraductal growth type (n=3). Diagnostic features of these four types were studied. Peripheral enhancement was a common angiographic feature and tumor stains were recognized in 88%, 20%, 0%, 33%, respectively. Angiography and dynamic computed tomography (D-CT) were useful in differential diagnosis with hepatocellular carcinoma. Accuracy rate in diagnosis of portal vein involvement by angiography and D-CT was 82% and 91%, respectively. MRI was more useful in tumor detection than D-CT in cases with attenuation difference, in 55% of type II and in 75% of type III. Increase of arterial involvement, biliary tract involvement and portal vein involvement, incidence of lymph nodes metastases became ...

1998-08-01

387

Benign and malign pulmonary tumors in childhood; Benigne und maligne Lungentumoren im Kindesalter  

Energy Technology Data Exchange (ETDEWEB)

Pulmonary tumors in children are rare. Nevertheless, there are besides malign primary neoplasms and metastases also some benign tumors that the radiologist should know. The identification of some tumors is difficult, since some of them may mimic pulmonary inflammation. The first diagnostic tool is chest radiography. After that, a CT with contrastmedium should be performed, if possible a multislice-CT (MSCT). Identification of mediastinal structures is best with MRI. (orig.) [German] Tumoren der Lunge sind im Kindesalter selten. Trotzdem finden sich neben den malignen primaeren und sekundaeren Raumforderungen auch im Kindesalter immer wieder benigne Tumoren, die der Radiologe kennen sollte. Eine eindeutige Identifizierung kann schwierig sein, da z. B. entzuendliche Infiltrate vorgetaeuscht werden koennen. Die primaere Untersuchungsmethode ist das konventionelle Thoraxroentgen. Die weitere Diagnostik muss mit der Computertomographie, nach Moeglichkeit mit einem ...

2003-12-01

388

Aggressive Ewing's sarcoma appearing as a cold lesion on bone scan  

International Nuclear Information System (INIS)

Ewing's sarcoma classically presents as a hot spot on bone scan as a result of increased vascularity of the tumor and new bone formation. Purpose We report and analyze an uncommon pattern of a 'cold' lesion in Ewing's sarcoma on bone scan and its pathophysiologic significance. Case report A 15-year-old boy complaining of thigh pain. CT scan evoked Ewing's sarcoma or osteitis. MRI evoked chronic osteitis. Scintigraphy showed a fairly intense and heterogeneous uptake on the femoral lesion and no abnormal uptake elsewhere. Biopsy showed none pathologic pattern. Three months later, a second biopsy concluded to Ewing's sarcoma. Bone scan showed a larger lesion with peripheral intense uptake centered by enlarged 'cold' area in the left femoral diaphysis and no evident bone metastasis. The patient underwent chemotherapy and surgery. Three months later, bone scan showed extensive skeletal metastasis. Conclusion Ewing's sarcoma appears usually as an intense lesion on bone ...

2009-10-01

389

In vitro investigation of biological and technical prosthetic heart valves in MRI: evaluation of possible deflection and heating of the implants; In-vitro-Untersuchung von biologischen und technischen Herzklappenprothesen im MRT: Beurteilung moeglicher Anziehung und Erhitzung der Implantate  

Energy Technology Data Exchange (ETDEWEB)

Purpose: In vitro evaluation of possible deflection and heating of present-day prosthetic heart valves, 12 technical and 5 biological, were investigated using a 1.5 Tesla Siemens Vision system. Deflection was measured at the edge of a 1.5 Tesla superconducting magnet. Each valve was then submerged in a vial of a 1/1 electrolyte solution and temperature was measured before and after imaging with a turbo-spin-echo sequence (TR 5200 ms, TE 138 ms, Flip angle 180 C, acquisition time 10.5 minutes, length of echo train 29). MR imaging was performed with phase encoding parallel and perpendicular to the plane of the valves. Results: None of the investigated prosthetic heart valves was deflected. The maximal observed temperature rise was 0.5 C. During MR investigation of the prostheses, artifacts caused by metallic parts were less evident using a spin-echo sequence than a gradient-echo sequence. Conclusions: Patients with the tested present-day prosthetic heart valves can be safely imaged by ...

2000-02-01

390

the earth observer - Earth Observing System - NASA  

Science.gov (United States)

of satellite, aircraft and ground-based observations. In ..... swarm traps by Utah Department of Food and Agriculture (DAF) personnel. Preliminary Results ..... the 150th anniversary of the book's publication and the 200th anniversary of Darwin's birth. ...... cold war submarine missions to find that Arctic Ocean ...

391

Validation of Cultivation and PCR Methods for Diagnosis of Lyme Neuroborreliosis?  

UK PubMed Central (United Kingdom)

Borrelial infection may manifest with a wide range of clinical signs, and in many cases, microbiological findings are essential for a proper diagnosis. This study included 48 patients with a working...Full Text Available

2008-10-01

392

Using Regulatory and Epistatic Networks to Extend the Findings of a Genome Scan: Identifying the Gene Drivers of Pigmentation in Merino Sheep  

UK PubMed Central (United Kingdom)

Extending genome wide association analysis by the inclusion of gene expression data may assist in the dissection of complex traits. We examined piebald, a pigmentation phenotype in both human and Merino...Full Text Available

393

The relative roles of bipolar disorder and psychomotor agitation in substance dependence  

UK PubMed Central (United Kingdom)

Previous studies have shown that both bipolar disorder (BPD) and psychomotor agitation (PMA) are associated with substance dependence. These two findings have yet to be integrated, despite evidence...Full Text Available

2010-06-01

394

The discovery of signal transduction by G proteins. A personal account and an overview of the initial findings and contributions that led to our present understanding  

UK PubMed Central (United Kingdom)

The realization that there existed a G-protein coupled signal transduction mechanism developed gradually and was initially the result of an ill fated quest for uncovering the mechanism of action...Full Text Available

2007-04-01

395

The French national prospective cohort of patients co-infected with HIV and HCV (ANRS CO13 HEPAVIH): Early findings, 2006-2010  

UK PubMed Central (United Kingdom)

BackgroundIn France, it is estimated that 24% of HIV-infected patients are also infected with HCV. Longitudinal studies addressing clinical and public health questions related to...Full Text Available

396

Telephone reliability of the Frenchay Activity Index and EQ-5D amongst older adults  

UK PubMed Central (United Kingdom)

BackgroundOlder adults may find it problematic to attend hospital appointments due to the difficulty associated with travelling to, within and from a hospital facility for the purpose...Full Text Available

397

Survival of HIV-Infected Adolescents on Antiretroviral Therapy in Uganda: Findings from a Nationally Representative Cohort in Uganda  

UK PubMed Central (United Kingdom)

BackgroundAdolescents have been identified as a high-risk group for poor adherence to and defaulting from combination antiretroviral therapy (cART) care. However, data on outcomes...Full Text Available

398

Surgical management and outcome analysis of stage III pediatric empyema thoracis  

UK PubMed Central (United Kingdom)

Aim:Report of 125 pediatric patients of empyema thoracis treated by open decortication, highlighting the presentation, delay in referral, operative findings, the response...Full Text Available

2010-01-01

399

Study of particles trapped by a magnetic field  

Science.gov (United States)

A new type of radiation which occurs when particles are accelerated in the field of a longitudinal wave and in a transverse magnetic field is studied. The characteristics of such spontaneous radiation are obtained, and the influence of collective effects on the radiation is analyzed. The application of the findings to the theory of free electron lasers is discussed. 8 references.

1986-01-01

400

Spaceward Bound - Australia 2009 - Spaceward Bound - NASA  

Science.gov (United States)

In addition I have had many years been cooking for Scouts fund-raising events and a hundred and one sausage sizzles so I can find my way around a cooktop. ...

401

Solitary Fibrous Tumor of the Pancreas: Imaging Findings  

UK PubMed Central (United Kingdom)

We report here a case of a pathologically proven solitary fibrous tumor of the pancreas. A 54-year-old man was referred to our hospital for further evaluation of a pancreatic mass that was found incidentally....Full Text Available

2008-07-01

402

Smoking cessation and lung cancer risk in an Asian population: Findings from the Singapore Chinese Health Study  

UK PubMed Central (United Kingdom)

Background:Smoking cessation is an important strategy for reducing the harmful effects of tobacco, particularly in the prevention of lung cancer; however, prospective data on the...Full Text Available

2010-09-28

403

Smoking and Illicit Drug Use Associations With Early Versus Delayed Reproduction: Findings in a Young Adult Cohort of Australian Twins*  

UK PubMed Central (United Kingdom)

Objective:This article examines relationships between reproductive onset and lifetime history of smoking, regular smoking, and nicotine dependence, and cannabis and other illicit...Full Text Available

2009-09-01

404

Sex, Gender, and Pain: A Review of Recent Clinical and Experimental Findings  

UK PubMed Central (United Kingdom)

Sex-related influences on pain and analgesia have become a topic of tremendous scientific and clinical interest, especially in the last 10 to 15 years. Members of our research group published...Full Text Available

2009-05-01

405

Rubella screening and vaccination program for US Air Force trainees: an analysis of findings.  

UK PubMed Central (United Kingdom)

A preventive medicine program of rubella control for trainees at the Air Force Military Training Center, Lackland AFB, Texas, was begun in October 1977. Incoming trainees were screened for rubella susceptibility,...Full Text Available

1982-03-01

406

Retrospective identification and characterization of mild cognitive impairment from a prospective population cohort  

UK PubMed Central (United Kingdom)

ObjectivesMild Cognitive Impairment (MCI) case-finding criteria have low specificity in general population studies. The present study retrospectively identifies cases...Full Text Available

2010-08-01

407

Retrograde neuronal tracing with a deletion-mutant rabies virus  

UK PubMed Central (United Kingdom)

We have constructed a deletion-mutant rabies virus encoding EGFP and find it to be an excellent tool for studying detailed morphology and physiology of neurons projecting to injection sites...Full Text Available

2007-01-01

408

Relationship between mRNA secondary structure and sequence variability in Chloroplast genes: possible life history implications  

UK PubMed Central (United Kingdom)

BackgroundSynonymous sites are freer to vary because of redundancy in genetic code. Messenger RNA secondary structure restricts this freedom, as revealed by previous findings in...Full Text Available

409

Radioactivity of Tobacco Leaves and Radiation Dose Induced from Smoking  

UK PubMed Central (United Kingdom)

The radioactivity in tobacco leaves collected from 15 different regions of Greece and before cigarette production was studied in order to find out any association between the root uptake of radionuclides...Full Text Available

2009-02-01

410

Public interest in predictive genetic testing, including direct-to-consumer testing, for susceptibility to major depression: preliminary findings  

UK PubMed Central (United Kingdom)

The past decade has seen rapid advances in the identification of associations between candidate genes and a range of common multifactorial disorders. This paper evaluates public attitudes towards the...Full Text Available

2010-01-01

411

Problematic renal calculi presenting during pregnancy.  

UK PubMed Central (United Kingdom)

Urinary tract calculi presenting during pregnancy are rare, with less than 0.1% of pregnancies being associated with stones, the vast majority being asymptomatic and a chance finding. We outline six...Full Text Available

1996-03-01

412

Podcast The Large Hadron Collider and the Search for the Higgs-Boson  

CERN Document Server

When it was first developed, the standard model predicted a collection of particles, and thanks to more and more powerful colliders, physicsists have been able to find them all except one: the Higgs-Boson.

2008-01-01

413

Pharmacologically Induced Hypogonadism and Sexual Function in Healthy Young Women and Men  

UK PubMed Central (United Kingdom)

Studies fail to find uniform effects of age-related or induced hypogonadism on human sexual function. We examined the effects of induced hypogonadism on sexual function in healthy men and women...Full Text Available

2009-02-01

414

Particle creation if a cosmic string snaps  

CERN Document Server

We calculate the Bogolubov coefficients for a metric which describes the snapping of a cosmic string. If we insist on a matching condition for all times {\\it and} a particle interpretation, we find no particle creation.

1994-01-01

415

On the construction of approximations to continuous functions under integral boundary conditions  

British Library Electronic Table of Contents (United Kingdom)

On the basis of the resolvent of a simple differential operator, a method for finding approximations to continuous functions is constructed. In this method, both the approximated function and its approximations satisfy the given integral boundary condition.

2011-01-01

416

Novel Pathologic Findings Associated with Urinary Retention in a Mouse Model of Mucopolysaccharidosis Type IIIB  

UK PubMed Central (United Kingdom)

Mucopolysaccharidosis type IIIB (MPS IIIB; Sanfilippo syndrome type B) is a metabolic disorder with devastating clinical characteristics starting in early childhood and leading to premature death. A...Full Text Available

2009-04-01

417

Neoangiogenesis in early cervical cancer: Correlation between color Doppler findings and risk factors. A prospective observational study  

UK PubMed Central (United Kingdom)

BackgroundThe aim of the present article was to evaluate whether angiogenic parameters as assessed by transvaginal color Doppler ultrasound (TVCD) may predict those prognostic factors...Full Text Available

418

NAME=\\  

Wastenet

...In your area Get connected Farmers & growers news Training & events Poultry (laying) Poultry production can be a profitable enterprise for organic farmers and eggs are ... To find out more about organic poultry production download our free comprehensive introductory guide: Organic poultry production - an introductory guide [PDF, ...

419

Modern Techniques of Pain Management  

UK PubMed Central (United Kingdom)

Even clinicians who keep up with the research literature on pain mechanisms may find themselves uncertain when trying to bring these new theories down to practical application for a patient with pain....Full Text Available

1988-01-01

420

MR findings in acute Lyme disease affecting the knee. A case report  

Energy Technology Data Exchange (ETDEWEB)

In this paper we report a case with primarily unspecific arthralgia after surgical therapy of hallux valgus deformity and consecutive reflex sympathetic dystrophy in which MR led to the diagnosis of Lyme disease. (orig.)

2002-07-01

421

Lie Algebroids and Classification Problems in Geometry  

CERN Document Server

We show how one can associate to a given class of finite type G-structures a classifying Lie algebroid. The corresponding Lie groupoid gives models for the different geometries that one can find in the class, and encodes also the different types of symmetry groups.

2007-01-01

422

Lessons learned in developing community mental health care in Africa  

UK PubMed Central (United Kingdom)

This paper summarizes the findings for the African Region of the WPA Task Force on Steps, Obstacles and Mistakes to Avoid in the Implementation of Community Mental Health Care. We present an overview...Full Text Available

2010-10-01

423

Leaders in Social Networks, the Delicious Case  

UK PubMed Central (United Kingdom)

Finding pertinent information is not limited to search engines. Online communities can amplify the influence of a small number of power users for the benefit of all other users. Users' information foraging...Full Text Available

424

Laser-Assisted Single-Molecule Refolding (LASR)  

UK PubMed Central (United Kingdom)

To assemble into functional structures, biopolymers search for global minima through their folding potential energy surfaces to find the native conformation. However, this process can be hindered by...Full Text Available

2010-09-22

425

Impalpable Testis and Laparoscopy: When the Gonad Is Not Visualized  

UK PubMed Central (United Kingdom)

The diagnostic accuracy of laparoscopy for impalpable testis is well recognized. However, in some cases, laparoscopic findings may be misleading, and a viable gonad may be missed with significant medico-legal...Full Text Available

2004-01-01

426

Imaging Findings of Localized Lymphoid Hyperplasia of the Pancreas: a Case Report  

UK PubMed Central (United Kingdom)

We report here on a case of localized lymphoid hyperplasia of the pancreas in a 70-year-old man which manifested as double lesions (uncinate process and tail) in the organ. The lesions were incidentally...Full Text Available

2011-07-01

427

Identification of CTX-M-Type Extended-Spectrum-?-Lactamase Genes Using Real-Time PCR and Pyrosequencing?  

UK PubMed Central (United Kingdom)

CTX-M extended-spectrum β-lactamases (ESBLs) are increasingly prevalent worldwide among Escherichia coli bacteria, mostly in community-acquired urinary tract infections. Finding...Full Text Available

2007-01-01

428

High-energy reaction cross sections of light nuclei  

Energy Technology Data Exchange (ETDEWEB)

The high-energy reaction cross sections of Li and Be isotopes are calculated using a simplified Glauber model and densities constrained by the empirical binding energies. We find excellent agreement with experiment, reproducing the large increase for the most neutron-rich nuclei.

1989-03-01

429

Head and Neck Sentinel Lymph Node Biopsy: Current State of the Art  

UK PubMed Central (United Kingdom)

Sentinel node biopsy is an alternative to elective neck dissection for the management of T1/T2 oral and oro-pharyngeal squamous cell carcinomas and is also finding application to head and neck cancer...Full Text Available

430

Has general practitioner computing made a difference to patient care? A systematic review of published reports.  

UK PubMed Central (United Kingdom)

OBJECTIVE--To review findings from studies of the influence of desktop computers on primary care consultations. DESIGN--Systematic review of world reports from 1984 to 1994. SETTING--The computerised...Full Text Available

1995-09-30

431

HIV Medications and Risk for Cardiovascular Disease  

Medline Plus

... different personal wellness goals for you. HIV Health Management With a good medical team and a desire to reach wellness goals , people with HIV can have a virtually normal lifespan. Take the HIV Wellness Quiz Test your knowledge and find out where you need to learn ...

432

Gene-Environment Interactions in Schizophrenia: Review of Epidemiological Findings and Future Directions  

UK PubMed Central (United Kingdom)

Concern is building about high rates of schizophrenia in large cities, and among immigrants, cannabis users, and traumatized individuals, some of which likely reflects the causal influence of environmental...Full Text Available

2008-11-01

433

Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science  

UK PubMed Central (United Kingdom)

BackgroundMany interventions found to be effective in health services research studies fail to translate into meaningful patient care outcomes across multiple contexts. Health services...Full Text Available

434

Finding Dense Clusters via "Low Rank + Sparse" Decomposition  

CERN Document Server

Finding "densely connected clusters" in a graph is in general an important and well studied problem in the literature \\cite{Schaeffer}. It has various applications in pattern recognition, social networking and data mining \\cite{Duda,Mishra}. Recently, Ames and Vavasis have suggested a novel method for finding cliques in a graph by using convex optimization over the adjacency matrix of the graph \\cite{Ames, Ames2}. Also, there has been recent advances in decomposing a given matrix into its "low rank" and "sparse" components \\cite{Candes, Chandra}. In this paper, inspired by these results, we view "densely connected clusters" as imperfect cliques, where imperfections correspond missing edges, which are relatively sparse. We analyze the problem in a probabilistic setting and aim to detect disjointly planted clusters. Our main result basically suggests that, one can find \\emph{dense} clusters in a graph, as long as the ...

2011-01-01

435

Finding Autonomy in Birth*  

UK PubMed Central (United Kingdom)

Over the last several years, as cesarean deliveries have grown increasingly common, there has been a great deal of public and professional interest in the phenomenon of women ‘choosing’...Full Text Available

2009-01-01

436

Finding Answers: Information Needs of a Multidisciplinary Patient Care Team in an Emergency Department  

UK PubMed Central (United Kingdom)

Emergency Departments (ED) are fast-paced, information-intensive environments where patient care team members must address their information needs quickly and accurately. We conducted a qualitative...Full Text Available

2006-01-01

437

Evaluating professionalism in medical undergraduates using selected response questions: findings from an item response modelling study  

UK PubMed Central (United Kingdom)

BackgroundProfessionalism is a difficult construct to define in medical students but aspects of this concept may be important in predicting the risk of postgraduate misconduct. For...Full Text Available

438

Diesel engine exhaust and lung cancer: an unproven association.  

UK PubMed Central (United Kingdom)

The risk of lung cancer associated with diesel exhaust has been calculated from 14 case-control or cohort studies. We evaluated the findings from these studies to determine whether there is sufficient...Full Text Available

1995-09-01

439

Diagnosis of Ewing's sarcoma in the thoracic spine - problems in differential diagnosis  

International Nuclear Information System (INIS)

Spinal Ewing's sarcomas are rare and cause problems in differential diagnosis. The radiologic, nuclear medicine and CT findings in two children with histologically proven Ewing's sarcoma are presented and problems in differential diagnosis discussed. Biopsy should be done early. (orig.).

440

Development of a novel data mining tool to find cis-elements in rice gene promoter regions  

UK PubMed Central (United Kingdom)

BackgroundInformation on more than 35 000 full-length Oryza sativa cDNAs, together with associated microarray gene expression data collected under various treatment...Full Text Available

441

Development Document for Proposed Effluent Limitations Guidelines and New Source Performance Standards for the Ore Mining and Dressing: Point Source Category.  

Science.gov (United States)

This document presents the findings of an extensive study of the ore mining and dressing industry, for the purpose of developing effluent limitations guidelines for existing point sources and standards for performance new sources, to implement Sections 30...

1982-01-01

442

Destructive effects of smoking on molecular and genetic factors of periodontal disease  

UK PubMed Central (United Kingdom)

Many epidemiological evidences have proven the association between smoking and periodontal disease. The causality can be further established by linking findings of traditional epidemiological studies...Full Text Available

443

Deformation of CHS model  

Energy Technology Data Exchange (ETDEWEB)

We calculate mass spectrum of CHS model deformed by an exactly marginal operator, and find that there are tachyons which are not localized in the target space. Similar deformation is discussed in another CFT which corresponds to separated NS5-branes. A condensation of the tachyons is briefly argued.

2002-10-07

444

Coulomb scattering for scalar field in Schroedinger picture  

Energy Technology Data Exchange (ETDEWEB)

The scattering of a charged scalar field on Coulomb potential on de Sitter space-time is studied using the solution of the free Klein-Gordon equation. We find that the scattering amplitude is independent of the choice of the picture and in addition the total energy is conserved in the scattering process.

2008-07-31

445

Colon Mucinous Adenocarcinoma in Childhood: A Case Report with Emphasis on Image Findings  

UK PubMed Central (United Kingdom)

Colorectal cancer is extremely rare in children. We report a case of a 12-year-old boy who presented with a five-month history of weight loss and anorexia, associated with vomiting episodes, dizziness,...Full Text Available

2010-01-01

446

Clinical Signs and Pathology of Accidental Monensin Poisoning in Sheep  

UK PubMed Central (United Kingdom)

The clinical signs and postmortem findings in sheep from two flocks accidentally poisoned with monensin are described. Clinical signs began within 24 hours of exposure to monensin. In the acute stages...Full Text Available

1982-11-01

447

Clinical Significance of the Detection of Antinuclear Antibodies in Patients with Acute Hepatitis A  

UK PubMed Central (United Kingdom)

Background/AimsThe findings of several recent studies suggest that antinuclear antibodies (ANAs) are frequently detected in patients with acute hepatitis A (AHA). However, the clinical...Full Text Available

2011-09-01

448

Circadian Disruption and Metabolic Disease: Findings from Animal Models  

UK PubMed Central (United Kingdom)

Social opportunities and work demands have caused humans to become increasingly active during the late evening hours, leading to a shift from the predominantly diurnal lifestyle of our ancestors...Full Text Available

2010-10-01

449

Can Basic Risk Research Help in the Prevention of Childhood and Adolescent Depression? Examining a Cognitive and Emotional Regulation Approach  

UK PubMed Central (United Kingdom)

This paper aims to highlight ways in which basic research findings in the field of childhood and adolescent depression can help to inform and refine preventive intervention efforts. We selectively review...Full Text Available

2011-01-01

450

CT evaulation of thoracic and abdominal fatty masses  

International Nuclear Information System (INIS)

The diagnostic accuracy of computed tomography (CT) in several patterns of thoracic and abdominal fatty masses, has been examined. In selected cases our findings overlap the features of the recent literature. The possibility of surgical therapy in peculiar cases of adipose deposits, commonly esteemed benign, is considered.

1986-01-01

451

CT evaluation of acetabular fractures  

International Nuclear Information System (INIS)

The paper deals with sixteen cases of acetabular fractures studied with CT. After a short description of the normal CT findings, the different kind of fractures are reported. The usefulness of CT examination in evaluating acetabular fractures and their complications is confirmed both in conservative treatment and surgical approach.

1986-01-01

452

Bladder outlet obstruction in a 6-month-old alpaca secondary to pelvic displacement of the urinary bladder  

UK PubMed Central (United Kingdom)

AbstractA 6-month-old female alpaca was presented for stranguria. Based on the history, physical examination findings, and radiographic studies, the alpaca was diagnosed with bladder...Full Text Available

2005-03-01

453

Autoimmune pancreatitis with atypical imaging findings that mimicked an endocrine tumor  

UK PubMed Central (United Kingdom)

Autoimmune pancreatitis (AIP) is a rare cause of recurrent acute pancreatitis or chronic pancreatitis in middle-aged patients, and is characterised by a marked infiltration of lymphocytes and plasma...Full Text Available

2010-06-21

454

Anticancer effects of Chinese herbal medicine, science or myth?*  

UK PubMed Central (United Kingdom)

Currently there is considerable interest among oncologists to find anticancer drugs in Chinese herbal medicine (CHM). In the past, clinical data showed that some herbs possessed anticancer properties,...Full Text Available

2006-12-01

455

An experimental application of a social reinforcement approach to the problem of job-finding1  

UK PubMed Central (United Kingdom)

The current conception of the employment process is that positions become available, are publicized, and are filled by the most qualified job seekers. An alternative conception is proposed that social...Full Text Available

1973-01-01

456

Acamprosate and naltrexone treatment effects on ethanol and sucrose seeking and intake in ethanol-dependent and nondependent rats  

UK PubMed Central (United Kingdom)

RationaleTwo pharmacotherapies are approved for treating alcohol craving (acamprosate and naltrexone), but both have shown mixed findings in animals and humans.Full Text Available

2009-06-01

457

Absolute dimensions of unevolved O type close binaries  

Energy Technology Data Exchange (ETDEWEB)

A method is presented to derive the absolute dimensions of early-type detached binaries by combining the observed parameters with results of evolutionary computations. The method is used to obtain the absolute dimensions of nine close binaries. We find that most systems have an initial masss ratio near 1.

1984-03-15

458

A newly designed big cup nitinol stent for gastric outlet obstruction  

UK PubMed Central (United Kingdom)

AIM: To find out whether a newly designed big cup nitinol stent is suitable for treatment of patients with gastric outlet obstruction resulting from gastric cancer.METHODS: The new stent is composed...Full Text Available

2010-09-07

459

A Longitudinal Study of Non-Voice Mobile Phone Usage by Teens from an Underserved Urban Community  

CERN Document Server

We report a user study of over four months on the non-voice usage of mobile phones by teens from an underserved urban community in the USA where a community-wide, open-access Wi-Fi network exists. We instrumented the phones to record quantitative information regarding their usage and location in a privacy-respecting manner. We conducted focus group meetings and interviewed participants regularly for qualitative data. We present our findings on what applications our participants used and how their usage changed over time. The findings highlight the challenges to evaluating the usability of mobile systems and the value of long-term methodologies. Based on our findings, we analyze the unique values of mobile phones, as a platform technology. Our study shows that the usage is highly mobile, location-dependent, and serves multiple social purposes for the participants. Furthermore, we present concrete ...

2010-01-01

460

Value of computed Tomography in re-staging patients undergoing second-look laparotomy for ovarian cancer  

International Nuclear Information System (INIS)

Twenty-five patients with ovarian carcinoma who had been operated and treated with chemotherapy underwent clinical examination and CT before reintervention (second-look laparotomy) to detect the presence of eventual recurrences. The prediction of recurrence based on CT and clinical findings was compared with the surgical findings at reintervention. CT proved to be more accurate than clinical examination in detecting recurrences; this was especially true for masses in the abdominal cavity, with the exception of small peritoneal nodules. The authors suggest the use of CT for staging the patients candidate to reintervention. This might help to avoid reintervantion in patients with persistent disease and to plan treatment.

1991-01-01

461

Thermal properties of UPdSn and UCuSn  

International Nuclear Information System (INIS)

We report on the specific heat and the thermopower of UPdSn and UCuSn, both of which order antiferromagnetically at low temperatures. The compounds show similar behaviour in the specific heat, and the large magnetic-entropy changes around T_N are evidence for a large degree of 5f-electron localization. For both compounds, we find that thermopower results are consistent with the findings for the electrical resistance. While for UCuSn very abrupt changes at 25 and 60 K are observed for both quantities, more continuous changes at the magnetic transitions (25 and 40 K) are found for UPdSn. (orig.).

1996-09-24

462

The luminosity function of cluster pulsars  

CERN Document Server

We study luminosities of millisecond pulsars in globular clusters by fitting the observed luminosity distribution with single and double power laws. We use simulations to model the observed distribution as the brighter part of some parent distribution for Terzan 5 and try to find a model which simultaneously agrees with the observed diffuse radio flux, total predicted number of pulsars and observed luminosity distribution. We find that wide ranges of parameters for log-normal and power-law distributions give such good models. No clear difference between the luminosity distributions of millisecond pulsars in globular clusters and normal disk pulsars was seen.

2010-01-01

463

The influence of psychological contracts on the adjustment and organisational commitment among expatriates: An empirical study in Taiwan  

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this research is to investigate the influence of psychological contracts on the adjustment and organisational commitment of expatriates during international business assignments. The study also aims to investigate the influence of psychological barriers to expatriate adjustment. Design/methodology/approach - A unique survey questionnaire was developed to collect data from 219 Taiwanese business expatriates during the first quarter of 2007. A LISREL analysis is used to test the hypotheses of the research framework. Findings - The study finds that: perceived fulfilment of the psychological contracts of expatriates significantly influences both their adjustment to foreign situations and their organisational commitment; psychological barriers to adjustment have a negat...

2009-01-01

464

Stochastic Optimization Approaches for Solving Sudoku  

CERN Document Server

In this paper the Sudoku problem is solved using stochastic search techniques and these are: Cultural Genetic Algorithm (CGA), Repulsive Particle Swarm Optimization (RPSO), Quantum Simulated Annealing (QSA) and the Hybrid method that combines Genetic Algorithm with Simulated Annealing (HGASA). The results obtained show that the CGA, QSA and HGASA are able to solve the Sudoku puzzle with CGA finding a solution in 28 seconds, while QSA finding a solution in 65 seconds and HGASA in 1.447 seconds. This is mainly because HGASA combines the parallel searching of GA with the flexibility of SA. The RPSO was found to be unable to solve the puzzle.

2008-01-01

465

Static potential of open bosonic membranes  

Energy Technology Data Exchange (ETDEWEB)

We study the static potential of open bosonic membranes in the 1/d approximation, where d is the space-time dimensionality. For a fixed square boundary of side length R we find, in contrast to the string potential, no critical distance below which tachyons appear. Instead, we find a correction factor to the classical potential, V/sub cl/=kR/sup 2/, which for small distances shifts the perturbative ground state energy by a positive constant. We interpret the shift as the mass gap of this quantum membrane.

1989-03-30

466

Security control methods for CEDR  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this document is to summarize the findings of recent studies on the security problem in statistical databases and examine their applicability to the specific needs of CEDR. The document is organized as follows: In Section 2 we describe some general control methods which are available on most commercial database software. In Section 3 we provide a classification of statistical security methods. In Section 4 we analyze the type of users of CEDR and the security control methods which may be applied to each type. In Section 5 we summarize the findings of this study and recommend possible solutions.

1990-09-01

467

Possible Stratification Mechanism in Granular Mixtures  

CERN Document Server

We propose a mechanism to explain what occurs when a mixture of grains of different sizes and different shapes (i.e. different repose angles) is poured into a quasi-two-dimensional cell. Specifically, we develop a model that displays spontaneous stratification of the large and small grains in alternating layers. We find that the key requirement for stratification is a difference in the repose angles of the two pure species, a prediction confirmed by experimental findings. We also identify a kink mechanism that appears to describe essential aspects of the dynamics of stratification.

1997-01-01

468

Phase diagram and effective shape of semi-flexible colloidal rods and biopolymers  

CERN Document Server

We study suspensions of semi-flexible colloidal rods and biopolymers using an Onsager-type second-virial functional for a segmented-chain model. For suspensions of thin and thick fd virus particles we calculate phase diagrams in quantitative agreement with experimental observations, and we find their effective state-point dependent shape to be much shorter and thicker than the actual shape. We also calculate the stretching of worm-like micelles in a host fd virus solution, again finding agreement with experiments. For both systems, our results show that the fd virus stiffness can play a key role in system behavior.

2011-01-01

469

Nanocomposites: a review of technology and applications  

British Library Electronic Table of Contents (United Kingdom)

Purpose - This paper aims to describe the technology and applications of nanocomposite materials. Design/methodology/approach - This paper discusses products, applications and technological developments in polymer, ceramic and metal nanocomposites. It concludes with a brief consideration of electronic component applications. Findings - It is shown that polymer nanocomposites and the materials used in their production are commercially available and finding applications in several industries, including automotive, military, food, electronics and leisure, due to their enhanced mechanical, electrical and thermal properties. Ceramic and metallic nanocomposites are at an earlier stage of development and a critical issue to resolve is optimising the dispersion of nanomaterials in the matrices. Pa...

2011-01-01

470

Involvement of the chest and abdominal wall as a rare manifestation in Hodgkin's disease  

Energy Technology Data Exchange (ETDEWEB)

Radiological findings of chest and abdominal wall involvement in Hodgkin's disease are reported. This manifestation was diagnosed in one patient in the primary staging and in two patients during the course of the disease. Typical radiological findings are soft tissue masses in the chest and abdominal wall, in two cases with continous tumor growth of enlarged mediastinal lymphnodes into the anterior chest wall. The axial computed tomography is the best method to evaluate the extent of chest and abdominal wall involvement in Hodgkin's disease.

1983-03-01

471

Imaging findings of abdominal peripheral primitive neuroectodermal tumor: report of four cases with pathological correlation  

British Library Electronic Table of Contents (United Kingdom)

Peripheral primitive neuroectodermal tumors (peripheral PNETs) are rare in the abdomen. We report the imaging findings of four peripheral PNETs arising in the abdomen. Three were ill-demarcated tumors and one was a well-demarcated tumor, with extensive local invasion and lymph node metastasis in two cases, respectively. The tumors are of inhomogeneous attenuation and heterogeneous enhancement after intravenous administration of contrast materials. Although their imaging manifestations cannot distinguish them from other sarcomas, recognition of these imaging features may be helpful in suggesting the possibility of peripheral PNETs in some cases.

2009-01-01

472

Enhancing employability in the "ME generation"  

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to place all of the contributions to this special issue into a theoretical framework and to highlight the role that the so-called "information age mindset" has in the facilitation of employability skills. Design/methodology/approach - The paper discusses the major themes of this special issue. Findings - Undergraduate students do see the importance of technological innovation in the classroom but they see the development of experiential or work-based skills to be more important. Practical implications - Future curriculum design should consider the expectations and attitudes of the modern day undergraduate student to ensure that potential employability is maximised. Originality/value - The findings are placed into the wider context of the emerging fiel...

2010-01-01

473

Dimensionally Constrained Symbolic Regression  

CERN Document Server

We describe dimensionally constrained symbolic regression which has been developed for mass measurement in certain classes of events in high-energy physics (HEP). With symbolic regression, we can derive equations that are well known in HEP. However, in problems with large number of variables, we find that by constraining the terms allowed in the symbolic regression, convergence behavior is improved. Dimensionally constrained symbolic regression (DCSR) finds solutions with much better fitness than is normally possible with symbolic regression. In some cases, novel solutions are found.

2011-01-01

474

Computerized tomography of adrenal glands in the investigation of Cushing's syn  

International Nuclear Information System (INIS)

Computerized tomography of the adrenal glands was performed in 10 patients with Cushing's syndrome using a G.E. 8800 CT/T Body Scanner. The tomographic findings of unilateral adrenal masses in 4 patients were confirmed by surgery. In the remaining 6 patients, computerized tomography did not identify any masses, and both glands were well visualized and showed normal shape. In these patients, measurement of the adrenal glands revealed both normal (n=1) and enlarged glands (n=5). The findings of adrenalectomy (n=4) or transphenoidal surgery and follow-up (n=2) established the diagnosis of adrenal phyperplasia in all patients. (Author).

475

Computerized tomography in the diagnosis and follow up in three observations of primitive suprasellar germinoma  

International Nuclear Information System (INIS)

Three cases of primitive suprasellar germinomas are reported: the tumors show typical clinical signs (diabetes insipidus, disfunctions), but CT findings are not so specific. It is very important to reach a correct diagnosis based on clinical and radiological findings, because of very high radiosensibility of the tumor. The accuracy of preoparative diagnosis has been enhanced by CT in addition to conventional neuroradiological examinations. Due to the possible risk of meningeal spreading following biopsy, some authors prefer to avoid biopsy and to treat directly the patient by radiotherapy; a rapid reduction of the tumor size at the dose of 30 Gy suggest a possible germinoma.

1986-01-01

476

Closed string tachyons and their implications for non-supersymmetric strings  

Energy Technology Data Exchange (ETDEWEB)

Closed string tachyons have long been somewhat mysterious. We note that there is often a regime in the classical moduli space in which one can systematically compute the effective action for such fields. In this regime, the tachyon is light, and cannot be integrated out. Instead, one must consider the combined dynamics of gravitons, moduli, tachyons and other light fields. We compute the action and find that the quartic term for the tachyon is positive in the field definition where the tachyon has no derivative coupling to the radion. We study the evolution of isotropic, homogeneous configurations and find that typically the system is driven to regions where the calculation is no longer under control. (author)

2004-07-01

477

CT colonography and cost-effectiveness  

Energy Technology Data Exchange (ETDEWEB)

CT colonography (CTC) is increasingly advocated as an effective initial screening tool for colorectal cancer. Nowadays, policy-makers are increasingly interested in cost-effectiveness issues. A number of studies assessing the cost-effectiveness of CTC have been published to date. The majority of findings indicate that CTC is probably not cost-effective when colonoscopy is available, but this conclusion is sensitive to a number of key parameters. This review discusses the findings of these studies, and considers those factors which most influence final conclusions, notably intervention costs, compliance rates, effectiveness of colonoscopy, and the assumed prevalence and natural history of diminutive advanced polyps. (orig.)

2008-11-15

478

Asset Prices, Liquidity, and Monetary Policy in an Exchange Economy  

British Library Electronic Table of Contents (United Kingdom)

I formulate a model in which money coexists with equity shares on a risky aggregate endowment. Agents can use equity as a means of payment, so shocks to equity prices translate into aggregate liquidity shocks that disrupt the mechanism of exchange. I characterize a family of optimal monetary policies and find that the resulting equity prices are independent of monetary considerations. I also study a perturbation of the family of optimal policies that targets a positive constant nominal interest rate and find that in this case the real equity return includes a liquidity return that depends on monetary considerations.

2011-01-01

479

A lethal form of Gorham disease associated with extensive musculoskeletal pneumatosis: case report and review of the literature  

Energy Technology Data Exchange (ETDEWEB)

We report here the imaging findings of a rare case of a lethal form of Gorham disease in a young female patient. Multimodality imaging findings over 13 year-follow-up demonstrated progressive wide spread skeletal and soft tissue abnormalities with permeative osteolysis, pathological fractures and severe skeletal deformities. Unusual extensive osseous and soft tissue pneumatosis was illustrated on cross-sectional studies. The progressive nature of this form of Gorham disease and the subsequent complications eventually culminated in patient's death. (orig.)

2008-11-15

480

A lethal form of Gorham disease associated with extensive musculoskeletal pneumatosis: case report and review of the literature  

International Nuclear Information System (INIS)

We report here the imaging findings of a rare case of a lethal form of Gorham disease in a young female patient. Multimodality imaging findings over 13 year-follow-up demonstrated progressive wide spread skeletal and soft tissue abnormalities with permeative osteolysis, pathological fractures and severe skeletal deformities. Unusual extensive osseous and soft tissue pneumatosis was illustrated on cross-sectional studies. The progressive nature of this form of Gorham disease and the subsequent complications eventually culminated in patient's death. (orig.)

2008-11-01

481

Measuring q sub 0 using supernovae at z approx 0. 3  

Energy Technology Data Exchange (ETDEWEB)

The measurement of q{sub o} is extremely important for understanding the quantity of matter in our universe. The measurement of q{sub o} using supernovae of type Ia as standard candles is appealing because it requires less modeling than other methods using galaxies. The challenge with using supernovae to measure q{sub o} is in finding enough of them. In order to find supernovas, we have constructed a very popular f/1 camera for the 3.9m Anglo-Australian Telescope. The camera uses reducing optics that put a 17 in. {times} 17 in. field on a 1024 {times} 1024 pixel Thomson CCD. Using this system, we image to 23rd magnitude in five minutes. We have developed a software package that uses image subtraction to find supernovae that are approximately magnitude 22.4 or brighter in these images. One field can be processed every 6.6 minutes on a relatively unloaded VAX 6000-6510. We estimate that this system should ...

1992-07-01

482

MR findings in cases of suspected impacted fracture of the femoral neck  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To evaluate MR imaging of the hip in patients with a clinically suspected impacted fracture of the femoral neck in cases where conventional plain films show negative or equivocal findings. Material and Methods: Twenty-seven such patients were prospectively examined by MR imaging with a 1.0 T unit, within 24 hours of admittance to hospital. A coronal T1-weighted turbo spin-echo sequence (n=27), and a coronal STIR sequence (n=25) or a coronal T2-weighted turbo spin-echo fast saturation sequence (n=2) were used. The evaluations were made by 2 radiologists with experience in musculoskeletal radiology. Results: There were 6 patients with a petrochanteric fracture, 2 without and 4 with slight displacement. Five patients had an impacted fracture of the femoral neck, and 3 had a fracture of the superior pubic bone. Of 2 patients with advanced arthrosis, i had an impacted femoral neck fracture and the other a nondisplaced intertrochanteric fracture. There was 1 ...

1997-09-01

483

Multislice helical CT in the diagnosis of hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Objective: To investigate the value ofMSCT in observing the direct findings of hilar cholangiocarcinoma1Methods Multislice helical CT studies were performed on the upper abdomen in 19 consecutive patientswith painless jaundice1 Precontrast and dynamic contrast enhanced (25 s phase and 60 s phase) scanswere conducted, and 3D imageswere reconstructed using enhanced raw data in 15 cases1 The direct CT findings of hilar cholangiocarcinoma were studied by three radiologists respectively in a 32scale strategy1 The morphological features and extension of bile duct involvement by hilar cholangiocarcinoma were analyzed1 All the 19 caseswere pathologically p roved as hilar cholangiocarcinoma by surgery (15 cases) and ERCP ( 4 cases) 1 Results The direct findings and extension of hilar cholangiocarcinoma could be demonstrated in 14 out of 15 3D reconstruction images, 8 out of 19 in 25 s phase, and 7 out of 19 in 60 s phase of contrast ...

2005-11-01

484

CT findings of intrahepatic cholangiocarcinoma associated with hepatolithiasis  

International Nuclear Information System (INIS)

To assess the CT findings of intrahepatic cholangiocarcinoma associated with hepatolithiasis. The CT features of 26 patients with cholangiocarcinoma and hepatolithiasis were reviewed and compared with those of 23 patients with intrahepatic stones alone, acting as control subjects. CT findings were analyzed for tumor appearance and adjacency to hepatolithiasis. We studied clinical findings, noting the presence or absence of wall thickening or soft tissue attenuation within the bile duct, the luminal diameter of dilated bile duct, and the presence of periductal enhancement, and compared these with the findings for control groups. CT images of the tumor revealed a hepatic low-attenuating mass with peripheral rim enhancement(n = 14,54 %), or periductal thickening, or low-attenuating lesions in segmental dilatation of intrahepataic bile ducts(n = 12, 46 %). Most hepatic tumors were seen in areas adjacent to ...

1999-09-01

485

SPIO-enhanced MR angiography for the detection of venous thrombosis in an animal model; SPIO-unterstuetzte MR-Angiographie zur Detektion venoeser Thromben im Tiermodell  

Energy Technology Data Exchange (ETDEWEB)

Purpose: An animal model is used to investigate whether MR angiography combined with super-paramagnetic particles of iron oxide (SPIO) is suitable for detecting thromboses. Methods: 42 rats in groups of 7 each were examined on days 1, 3, 5, 7, 9 and 11, respectively, after mechanical/chemical thrombus induction in a 1.5 Tesla magnet with a FISP sequence (TR/TE/FA 50 ms/6 ms/40 ). Imaging was performed before and up to 90 minutes after intravenous injection of 30 {mu}mol FE/kg BW of the experimental SPIO (hydrodynamic diameter, 34{+-}17 nm LLS; R1 and R2 relaxivity at 0.47 T, 31 and 57 L/(mmol*s)). MIP reconstructions of MR angiographies were submitted to consensus assessment by two examiners using histology as the gold standard. Results: The image quality of MIP reconstructions was rated as good in 38 of 42 cases. With regard to thrombotic vessel occlusion, MR angiography coincided with histology in 17 of 42 cases and differed in 25, lumen narrowing being overestimated by ...

1999-03-01

486

Determination of cartilage thickness in the ankle joint. MRT (1,5 T) comparative anatomical study; Bestimmung der Knorpeldicke am oberen Sprunggelenk. Eine MRT(1,5 T)-anatomische Vergleichsstudie  

Energy Technology Data Exchange (ETDEWEB)

Purpose: The aim of this study was to evaluate the accuracy of MRI in the measurement of cartilage thickness of the ankle joint in comparison to pathologic and histologic specimens. Patients and methods: The ankle joints of four fresh cadaver feet were imaged on a 1.5 T MR-unit in the coronal plane. Standard T{sub 1}-weighted spin echo (SE) and a T{sub 1}-weighted 3D-GE (FLASH-3D) sequence with fat saturation were applied. Following MR imaging, the talus was explanted and cut parallel to the MR images for macroscopic evaluation and histologic specimens were prepared. MRI measurements of the cartilage thickness of the talus were carried out in two ways: Without and with consideration of a transition zone of intermediate signal intensity between hyperintense cartilage and hypointense cortical bone. The data were compared with the anatomic specimens as the gold standard expressing the difference as a percentage value. On histologic specimens ...

1997-04-01

487

Travelling wave solutions to the Kuramoto-Sivashinsky equation  

International Nuclear Information System (INIS)

Combining the approaches given by Baldwin [Baldwin D et al. Symbolic computation of exact solutions expressible in hyperbolic and elliptic functions for nonlinear PDEs. J Symbol Comput 2004;37:669-705], Peng [Peng YZ. A polynomial expansion method and new general solitary wave solutions to KS equation. Comm Theor Phys 2003;39:641-2] and by Schuermann [Schuermann HW, Serov VS. Weierstrass' solutions to certain nonlinear wave and evolution equations. Proc progress electromagnetics research symposium, 28-31 March 2004, Pisa. p. 651-4; Schuermann HW. Traveling-wave solutions to the cubic-quintic nonlinear Schroedinger equation. Phys Rev E 1996;54:4312-20] leads to a method for finding exact travelling wave solutions of nonlinear wave and evolution equations (NLWEE). The first idea is to generalize ansaetze given by Baldwin and Peng to find elliptic solutions of NLWEEs. Secondly, conditions used by Schuermann to find physical ...

2007-08-01

488

Track clustering and vertexing algorithm for L1 trigger  

Energy Technology Data Exchange (ETDEWEB)

One of the keystones of the canceled BTeV experiment (proposed at Fermilab's Tevatron) was its sophisticated three-level trigger. The trigger was designed to reject 99.9% of light-quark background events and retain a large number of B decays. The BTeV Pixel Detector provided a 3-dimensional, high resolution tracking system to detect B signatures. The Level 1 pixel detector trigger was proposed as a two stage process, a track-segment finder and a vertex finder which analyzed every accelerator crossing. In simulations the track-segment finder stage outputs an average of 200 track-segments per accelerator crossing (2.5MHz). The vertexing stage finds vertices and associates track-segments with the vertices found. This paper proposes a novel adaptive pattern recognition model to find the number and the estimated location of vertices, and to cluster track-segments around those vertices. The track clustering and vertex ...

2005-10-01

489

The role of Computerized Tomography in osteoid-osteoma diagnosis  

International Nuclear Information System (INIS)

Alcaptonuria is a rare autosomal recessive metabolic disease, due to the lack of homogentisic acid oxidase. The following accumulation of homogentisic acid brings about a black discoloration of both the urine alcaptonuria) and connective tissue (ochronosis). The ochronotic alterations into joint cartilages cause degenerative arthropathy and osteopenia. The radiological features of three unrelated cases of alcaptonuria are reported. Radiographic abnormalities of ochconotic arthropathy are found in both the spine and the extraspinal joints. In the spine, the progressive calcification and ''vacuum'' phenomenon of disc spaces are the most characteristic findings. Disc space narrowing is associated with calcification and marginal sclerosis of vertebral bodies and is accentuated by osteopenia. Osteophytes are usually absent or of small size; neverthless progressive formation of marginal intervertebral bridges and obliteration of disc spaces at multiple levels ...

1988-01-01

490

Technology for enhancing chest auscultation in clinical simulation.  

Science.gov (United States)

The ability to use an acoustic stethoscope to detect lung and/or heart sounds, and then to then communicate one's interpretation of those sounds is an essential skill for many medical professionals. Interpretation of lung and heart sounds, in the context of history and other examination findings, often aids the differential diagnosis. Bedside assessment of changing auscultation findings may also guide treatment. Learning lung and heart auscultation skills typically involves listening to pre-recorded normal and adventitious sounds, often followed by laboratory instruction to guide stethoscope placement, and finally correlating the sounds with the associated pathophysiology and pathology. Recently, medical simulation has become an important tool for teaching prior to clinical practice, and for evaluating bedside auscultation skills. When simulating cardiovascular or pulmonary problems, high-quality lung and heart sounds should be able to ...

2011-02-11

491

Spamology: A Study of Spam Origins  

Energy Technology Data Exchange (ETDEWEB)

The rise of spam in the last decade has been staggering, with the rate of spam exceeding that of legitimate email. While conjectures exist on how spammers gain access to email addresses to spam, most work in the area of spam containment has either focused on better spam filtering methodologies or on understanding the botnets commonly used to send spam. In this paper, we aim to understand the origins of spam. We post dedicated email addresses to record how and where spammers go to obtain email addresses. We find that posting an email address on public Web pages yields immediate and high-volume spam. Surprisingly, even simple email obfuscation approaches are still sufficient today to prevent spammers from harvesting emails. We also find that attempts to find open relays continue to be popular among spammers. The insights we gain on the use of Web crawlers used to harvest email addresses and the commonalities of techniques ...

2009-07-01

492

Radionuclear estimation with {sup 99m}Tc-N-pyridoxyl-5-methyl-tryptophan (PMT) scintigraphy of recurrent hepatocellular carcinoma after non-surgical treatment  

Energy Technology Data Exchange (ETDEWEB)

{sup 99m}Tc-N-pyridoxyl-5-methyl-tryptophan (PMT) scintigraphy, which exhibits highly specific for the diagnosis of primary hepatocellular carcinoma (HCC), was performed for recurrent HCC following non-surgical treatment. Eighty-four patients (total 351 examinations) were selected for the study. The ability of PMT scintigraphy to diagnose recurrent HCC after treatment was compared with that of computed tomography, ultrasonography and angiography. The results showed that sixty-three (75%) of 84 cases demonstrated positive findings during our follow-up period, most of the tumors initially showing positive findings remained PMT positive when they recurred and PMT studies shortly after treatment demonstrated wider tracer uptake rather than the actual tumor area. In conclusion, PMT scintigraphy for patients with HCC after non-surgical treatment exhibited high accuracy in identifying viable HCC only for tumors indicating positive ...

1997-10-01

493

Phenomenology of a light gluon resonance in top-physics at Tevatron and LHC  

CERN Document Server

We present a phenomenological analysis of the recent Tevatron results on the $t \\bar t$ forward-backward asymmetry and invariant-mass spectrum assuming a new contribution from an s-channel gluon resonance with a mass in the range from 700 to 2500 GeV. In contrast to most of the previous works, this analysis shows that for masses below ~1 TeV resonant New Physics could accommodate the experimental data. In general, we find that axial-like couplings are preferred for light and top quark couplings, and that only top quark couples strongly to New Physics. We find that composite model scenarios arise naturally from only phenomenological analyses of the experimental results. We show that our results are compatible with recent LHC limits in dijet and $t \\bar t$ production, and find some tension for large resonance mass ~2.5 TeV. We indicate as best observables for discriminating a relatively light new gluon a better resolution ...

2011-01-01

494

On higher derivative corrections of tachyon action  

Energy Technology Data Exchange (ETDEWEB)

We have examined the momentum expansion of the disk level S-matrix element of two tachyons and two gauge fields to find, up to on-shell ambiguity, the couplings of these fields in the world volume theory of N coincident non-BPS D-branes to all order of {alpha}'. Using the proposal that the action of D-brane-anti-D-brane is given by the projection of the action of two non-BPS D-branes with (-1){sup F{sub L}}, we find the corresponding couplings in the world volume theory of the brane-anti-brane system. Using these infinite tower of couplings, we then calculate the massless pole of the scattering amplitude of one RR field, two tachyons and one gauge field in the brane-anti-brane theory. We find that the massless pole of the field theory amplitude is exactly equal to the massless pole of the disk level S-matrix element of one RR, two tachyons and one gauge field to all order of {alpha}'. We have also found ...

2008-09-11

495

Long-term effects of prenatal x-ray of human females: reproductive experience  

Energy Technology Data Exchange (ETDEWEB)

A cohort of singleton black human females exposed to diagnostic x-ray in utero and controls matched by parity, hospital of birth and birthdate have been followed to ages 25 to 30 years in Baltimore, Maryland. The search for possible effects of prenatal irradiation has focused on health, growth, development, and reproductive experience of exposed and control women. This paper reports findings related to reproductive experience. From an original data set of 1458 matched exposed-control pairs of women, questionnaire responses were received from 1109 exposed and 1124 control women including 852 each from pairs in which both the exposed and control woman responded. After careful search for alternative explanations of the findings, the authors concluded that females exposed in utero to low doses of x-ray (probably 1 to 5 rads) had significant increases in their rates of early onset of menses, births at age 15 years or less, numbers of living ...

1981-09-01

496

Focal lesions in external auditory canal: computed tomography images  

International Nuclear Information System (INIS)

To analyze and review the most common focal lesions of the external auditory canal (EAC), describing the computed tomography (CT) findings. The CT images of EAC were reviewed in a series of 167 patients. Abnormal findings were recorded in 13 cases. The CT images were correlated with otoscopic and/or intraoperative findings. There were four cases of osteoma (one located outside the EAC); all of which were treated surgically, as was the one case of exostosis. Six patients presented debris in EAC, coinciding with clinical evidence of external otitis. There were two cholesteatomas derived from EAC, one of them secondary to survery to treat osteoma. On patient was diagnosed as having a basal cell carcinoma of the ear, extending to EAC, but refused to undergo surgery. Five patients presented small triangular laminae of dense bone arising from the upper wall of the EAC which were defined as abnormal variants of the fusion of the ...

497

Diagnostic Performance of Computed Tomography Colonography in Symptomatic Patients and in Patients with Increased Risk for Colorectal Disease  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To evaluate the diagnostic performance (colorectal lesions) of computed tomography (CT) colonography in 111 patients, a majority of whom were at high risk for colorectal neoplasia. Material and Methods: After bowel preparation, CT colonography was performed, immediately followed by conventional colonoscopy. The diagnostic performance of CT colonography was analyzed relative to lesion size, histological diagnosis, and diagnostic certainty. Results: The sensitivity of CT colonography increased with lesion size (P<0.001), and was 91% (21/23) for lesions > or = 10 mm. All 10 carcinomas and 86% (19/22) of adenomas > or = 5 mm were detected. Unconfirmed or false-positive CT findings were generally small and/or reported with low diagnostic certainty. The specificity of CT colonography would be 45% (30/66; 95% CI 34% to 57%) if patients with findings of any size and any diagnostic certainty were selected for follow-up, and ...

2006-11-15

498

Deforming the Maxwell-Sim algebra  

International Nuclear Information System (INIS)

The Maxwell algebra is a noncentral extension of the Poincare algebra, in which the momentum generators no longer commute, but satisfy [P?,P?]=Z??. The charges Z?? commute with the momenta, and transform tensorially under the action of the angular momentum generators. If one constructs an action for a massive particle, invariant under these symmetries, one finds that it satisfies the equations of motion of a charged particle interacting with a constant electromagnetic field via the Lorentz force. In this paper, we explore the analogous constructions where one starts instead with the ISim subalgebra of Poincare, this being the symmetry algebra of very special relativity. It admits an analogous noncentral extension, and we find that a particle action invariant under this Maxwell-Sim algebra again describes a particle subject to the ordinary Lorentz force. One can also deform the ISim algebra to DISimb, where b is a nontrivial dimensionless ...

2010-09-15

499

CT of blunt chest trauma in children  

Energy Technology Data Exchange (ETDEWEB)

While trauma is still the leading cause of death in the pediatric age range, it is surprising how little the CT appearances of pediatric chest injury have been investigated in the literature. We have reviewed the CT findings of blunt chest trauma in 44 children for whom chest CT examinations were requested to investigate the extent of intrathoracic injury. We noted a propensity for pulmonary contusions to be located posteriorly or posteromedially, and for them to be anatomically nonsegmental and crescentic in shape. This is possibly attributable to the relatively compliant anterior chest wall in children. The CT appearances of other major thoracic injuries are described, including pulmonary lacerations, pneumothoraces, malpositioned chest tubes, mediastinal hematomas, aortic injury, tracheobronchial injury, hemopericardium, and spinal injuries with paraspinal fluid collections. Children demonstrating findings incidental to the actual injury yet ...

1993-03-01

500

2001 Report on the Next Linear Collider  

Energy Technology Data Exchange (ETDEWEB)

Recent studies in elementary particle physics have made the need for an e{sup +}e{sup -} linear collider able to reach energies of 500 GeV and above with high luminosity more compelling than ever [1]. Observations and measurements completed in the last five years at the SLC (SLAC), LEP (CERN), and the Tevatron (FNAL) can be explained only by the existence of at least one particle or interaction that has not yet been directly observed in experiment. The Higgs boson of the Standard Model could be that particle. The data point strongly to a mass for the Higgs boson that is just beyond the reach of existing colliders. This brings great urgency and excitement to the potential for discovery at the upgraded Tevatron early in this decade, and almost assures that later experiments at the LHC will find new physics. But the next generation of experiments to be mounted by the world-wide particle physics community must not only find this new physics, they ...

2001-08-28