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Attention Deficit Hyperactivity Disorder

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Russian 2004 p. 50-51 Russian Federation Kalyakin, SG Kapinos,

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Studies that estimate deficit probabilities in hydrothermal systems have generally ignored the response of demand to changing prices, in the belief that such response is largely irrelevant. We show that ignoring the response of demand to prices can lead to substantial over or under estimation of the probability of an energy deficit. To make our point we present an estimation of deficit probabilities in Chile's Central Interconnected System between 2006 and 2010. This period is characterized by tight supply, fast consumption growth and rising electricity prices. When the response of demand to rising prices is acknowledged, forecasted deficit probabilities and marginal costs are shown to be substantially lower. (author)

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BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a common condition that often results in child and family functional impairments. Although there are evidence-based treatment...Full Text Available

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A field experiment was conducted during the summer of 1988 to test the hypothesis that water deficit affects the abscisic acid (ABA) and indole acetic acid (IAA) concentrations in cotton (Gossypium...Full Text Available

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Dysregulation of glutamate neurotransmission may play a role in cognitive deficits in schizophrenia. Manipulation of glutamate signaling using drugs acting at metabotropic glutamate receptors...Full Text Available

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BackgroundThe ACTION study (Attention deficit hyperactivity disorder Controlled Trial Investigation Of a Non-stimulant) is a multi-center, double-blind, randomized...Full Text Available

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... which extend beyond the upper airway. These include attention deficit hyperactivity disorder, learning disorders, failure to thrive, and enuresis. Tonsillectomies ...

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The specific binding of transcription factors to cognate sequence elements is thought to be critical for the generation of specific gene expression programs. Members of the nuclear factor κB...Full Text Available

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The MiniBooNE experiment [1] is motivated by the LSND observation, [2] which has been interpreted as {nu}{sub {mu}} {yields} {nu}{sub e} oscillations, and by the atmospheric neutrino deficit, [3,4,5] which may be ascribed to {nu}{sub {mu}} oscillations into another type of neutrino. MiniBooNE is a single-detector experiment designed to: obtain {approx} 1000 {nu}{sub {mu}} {yields} {nu}{sub e} events if the LSND signal is due to {nu}{sub {mu}} {yields} {nu}{sub e} oscillations, establishing the oscillation signal at the > 5{sigma} level as shown in Fig. 1.1; extend the search for {nu}{sub {mu}} {yields} {nu}{sub e} oscillations significantly beyond what has been studied previously if no signal is observed; search for {nu}{sub {mu}} disappearance to address the atmospheric neutrino deficit with a signal that is a suppression of the rate of {nu}{sub {mu}}C {yields} {mu}N events from the expected 600,000 per year; ...

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... Abuse (162) Alcoholism (12) Anxiety Disorders & Phobias (4) Attention-Deficit-Hyperactivity Disorder (3) B Binge Drinking (37) Bipolar Disorder (1) ...

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We have recently reported that spontaneously hypertensive rats (SHRs) exhibit a deficit in contextual fear conditioning that is specifically reversed by antipsychotic and potentiated by psychostimulants and other manipulations thought to produce schizophrenia-like states in rodents. Based on these findings, we suggested that this deficit in fear conditioning could be used as an experimental model of emotional processing impairments observed in schizophrenia. This strain has also been suggested as a model by which to study attention deficit/hyperactivity disorder (ADHD). Considering that schizophrenia and ADHD are both characterized by poor social function, this study aimed to investigate possible behavioral deficits of SHRs in a social context. Furthermore, we sought to examine the effects...

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Whether or not a current account deficit sustainable has important implications for policy. If the current account deficits of a nation is sustainable, then it implies that the government should have no incentive to default on its international debt. In this article we examine whether or not the current account deficits for the OECD countries can be characterized by a unit root process with regime switching. The econometric methodology allows us to distinguish periods that are associated with unsustainable outcomes from those in which the intertemporal national long-run budget constraint (LRBC) holds. Among the main results, it is found that it is very likely that the LRBC will not hold for the Australia, the Czech Republic, Finland, Hungary, New Zealand, Portugal or Spain, thus signifying...

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... The effectiveness of immune suppression with both 6-mercaptopurine and methotrexate was insufficient to permit induction of a clinically useful ...

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This study examined changes in the degree of positive bias in self-perceptions of previously-diagnosed 8 to 13 year-old children with attention-deficit/hyperactivity disorder (ADHD) (n=513)...Full Text Available

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Mouse lines with behavioral phenotypes relevant to symptoms in neurodevelopmental disorders may provide models to test hypotheses about disease etiology and to evaluate potential treatments....Full Text Available

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AimsTo describe nurse burnout, job dissatisfaction, and quality of care in Japanese hospitals, and to determine how these outcomes are associated with work environment...Full Text Available

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BackgroundThe long-term neurotoxicity risks caused by prenatal exposures to pesticides are unclear, but a previous pilot study of Ecuadorian school children suggested that blood...Full Text Available

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Congenital deformities involving the coverings of the nervous system are called neural tube defects (NTDs). NTD can be classified as neurulation defects, which occur by stage 12, and postneurulation...Full Text Available

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The compromised abilities to localize sounds and to understand speech are two hallmark deficits in aged individuals. The auditory cortex is necessary for these processes, yet we know little...Full Text Available

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While estrogen (E2) is thought to play an important role in age-related cognitive decline, neuronal plasticity, as well as the pathogenesis of Alzheimer disease (AD), the mechanisms by which...Full Text Available

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We investigated the effects of P_SARK∷IPT (for Senescence-Associated Receptor Kinase∷Isopentenyltransferase) expression and cytokinin production...Full Text Available

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Published rates of comorbidity between pediatric bipolar disorder (PBD) and attention-deficit/hyperactivity disorder (ADHD) have been higher than would be expected if they were independent conditions,...Full Text Available

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Water-maze testing has been used to assess prenatal cocaine (PCOC)- induced deficits in behavioral studies of spatial navigation and memory abilities. Effects of PCOC in acquisition or in probe...Full Text Available

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Methylphenidate (MPH) is commonly prescribed in childhood and adolescence for the treatment of attention–deficit/hyperactivity disorders. In rodents, MPH exposure during preadolescence...Full Text Available

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The relationship of attention-deficit/hyperactivity disorder (ADHD) to learning disorders was reviewed and included reading disability, mathematics learning disability, and nonverbal learning disability. Genetic, neuroimaging, and neuropsychological functioning were examined for each disorder, along with a discussion of any existing literature when ADHD co-occurred with the disorder. All the disorders were found to frequently co-occur with ADHD. A review of the underlying neuroanatomic and neurofunctional data found specific structures that frequently co-occur in these disorders with others that are specific to the individual diagnosis. Aberrations in structure and/or function were found for the caudate, corpus callosum, and cerebellum, making these structures sensitive for the disorder bu...

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The mechanism of influenza virus (INFV)-induced immunosuppression and the mode of inosiplex action against INFV infection were studied. INFV suppressed both anti-lipopolysaccharide and anti-sheep erythrocyte...Full Text Available

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Increased sensitivity to light-induced melatonin suppression characterizes some, but not all, patients with bipolar illness or seasonal affective disorder. The aim of this study was to test...Full Text Available

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... Abstract : The acousto-optic filter (AOF) is ... for large switch networks. ... FOURIER TRANSFORMATION, OPTICAL SWITCHING, SURFACE ACOUSTIC ...

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The effect of ultrasound waves, airflow and combined ultrasound with the airflow on the thermal instability suppression of a hollow needle-to-plate electrical discharge was studied experimentally. To evaluate the thermal instability suppression we used the V-A characteristics of the discharge in stationary air, with ultrasound applied in stationary air, and finally when the airflow was supplied into the discharge through the needle without and with ultrasound application. To illustrate the effect of ultrasound, airflow and combined ultrasound with airflow on the discharge thermal instability suppression we also studied the discharge ozone production. We found that in stationary air the application of ultrasound only slightly suppresses thermal instability. A substantial increase of ozone generation was not detected. Application of the airflow through the needle suppressed ...

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Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurobehavioral disorder affecting 5% to 10% of children. Although considered to be a highly familial disorder, ADHD heritability estimates of 60% to 80% highlight the considerable role that environmental factors may still play in disorder susceptibility. Proposed ADHD environmental risk factors include prenatal substance exposures, heavy metal and chemical exposures, nutritional factors, and lifestyle/psychosocial factors. This paper reviews the literature published in 2010 investigating the association between environmental risk factors and ADHD or related symptomatology. Sources of risk factor exposure and the proposed mechanism by which each exposure is linked to ADHD-related neurobehavioral changes are also reported. Metho...

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Objectives To delineate the safety and tolerability profile of methylphenidate and atomoxetine in children and adolescents with attention deficit hyperactivity disorder (ADHD) monitored for more than 1?year. Design A cohort study analyzing data from the national ADHD register on patients from the Lombardy Region treated with MPH or atomoxetine. Participants A total of 229 children (median age 11?years, range 6?17), enrolled in 15 regional centers between June 2007 and May 2010. Results The prevalence rate of pharmacological treatment for ADHD was 0.23%, whereas the estimated ADHD prevalence in the population was 0.95%. In total, 73.8% of patients had been treated with atomoxetine (10?90?mg daily) or MPH (10?75?mg daily); 22% of patients also received an additional psychotropic drug. Of the...

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Pots used for experiments conducted on plants grown in them create rooting environments that are affected by limited soil volume, which can affect various physiological processes, including transpiration, and plant growth. However, the applicability of results from pot experiments to the field has received limited attention. The objective of this study was to compare the growth and transpiration of maize (Zea mays L.) and winter wheat (Triticum aestivum L.) when grown in pots and field plots under various constant water deficits. The experiments were conducted under similar environmental conditions for both pots and plots. Transpirational responses at both transient (RTTr) and daily (RDTr) time scales to a decreasing fraction of available soil water (FASW) were analyzed. For a comparable F...

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Harvested plant organs such as heads of broccoli (Brassica oleracea L. var. italica) experience a range of stresses that can lead to premature reduction in quality and eventual senescence. Understanding plant responses to stress may open up novel opportunities to extend postharvest life. One of the first stresses experienced by harvested organs is likely to be water deficit stress since severance of the vascular system halts the normal flux of water into the tissue. For broccoli branchlets with their cut ends held in water, transcriptome analysis based on hybridization of broccoli floret mRNA to a heterologous Arabidopsis microarray revealed that the transcript abundance of 431 genes reliably changed within 48h of harvest. Of these, transcripts of 146 genes increased and 34 genes decreased...

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The integral membrane protein synaptophysin is one of the most abundant polypeptide components of synaptic vesicles. It is not essential for neurotransmission despite its abundance but is believed to modulate the efficiency of the synaptic vesicle cycle. Detailed behavioral analyses were therefore performed on synaptophysin knockout mice to test whether synaptophysin affects higher brain functions. We find that these animals are more exploratory than their wild type counterparts examining novel objects more closely and intensely in an enriched open field arena. We also detect impairments in learning and memory, most notably reduced object novelty recognition and reduced spatial learning. These deficits are unlikely caused by impaired vision, since all electroretinographic parameters measur...

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Abstract The present study makes use of a detailed water balance to investigate the hydrological status of a peatland with a basal clay-rich layer overlying an aquifer exploited for drinking water. The aim is to determine the influence of climate and groundwater extraction on the water balance and water levels in the peatland. During the two-year period of monitoring, the hydrological functioning of the wetland showed a hydric deficit, associated with a permanent unsaturated layer and a deep water table. At the same time, a stream was observed serving as a recharge inflow instead of draining the peatland, as usually described in natural systems. Such conditions are not favourable for peat accumulation. Field investigations show that the clay layer has a high hydraulic conductivity (from 11...

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Driving is a complex task that can be a significant challenge for individuals with attention-deficit/hyperactivity disorder (ADHD). A slight lapse in attention or inhibition while driving (not uncommon in individuals with ADHD) can result in hazardous consequences for these individuals and their families. This is also an interesting clinical scenario for the treating physician, who is always trying to optimize the various treatment options for the patient. Despite such potentially perilous consequences for society, this subject only recently has received researchers? attention. This review paper highlights the psychological differences between drivers with and without ADHD and examines differences between these groups in various driving simulation models. Research updates involving pharmac...

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Effects of soil pH on damping-off of sugar beet by R. solani (AG2-2) and soil suppressiveness against the disease were studied by comparing disease incidences in pasteurized versus non-pasteurized, infested soils. Soil pH was correlated neither to disease incidence in five soils ranging from pH?4.5 to 7.2 nor to indigenous disease suppressiveness, the difference in disease incidences between non-treated soil and its pasteurized counterpart. When an alkaline soil was acidified with H2SO4, disease suppression markedly declined, increasing disease incidence in the non-pasteurized soil. Inversely, disease suppression was enhanced when an acidic soil was neutralized by adding Ca(OH)2. Soil amendment with dried peanut plant residue suppressed the disease in two pasteurized, near-neutral soils, l...

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This paper describes the observation and partial wave analysis of 1203 (22 GeV) #pi#"-p #-># phi phi n events. This is an OZI suppressed channel in which the OZI suppression is found to be absent. Assuming QCD and the OZI rule as Ansatzen, it is concluded that the breakdown of the OZI suppression is due to glueballs. The g/sub T/(2160) and the g/sub T/(2320) with I/sup G/J/sup PC/ = 0"+2"+"+ are two resonances determined from the partial wave analysis. It is concluded that one or two primary glueballs with the above quantum numbers are responsible for the observed two states. A brief discussion of other glueball candidates and some relevant phenomenology is also included.

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Describes general trends in the quality of rural education: equivalent rural and urban performance on national standardized tests and high school graduation rates but continuing rural deficits in college attendance and teacher qualifications. Discusses the below-average performance of southern rural schools, factors affecting rural students' college attendance, and the influence of changing labor markets. (SV)

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Bony craniofacial deficits resulting from injury, disease, or birth defects remain a considerable clinical challenge. In this study, microsphere-based scaffold fabrication methods were use to...Full Text Available

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Mechanisms, AGARD Conference Proceedings No. 131, 1974, Paper No. 11. ... Olsen, W. and Karchmer, A., Lip Noise Generated by Flow Separation From Nozzle ...

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Fusarium wilt is now a major disease of carnation crops worldwide. Methyl bromide, which is used to remedy it, is environmentally unsafe. An alternative approach integrated into biological control is to grow crops in suppressive media. Suppressiveness of seven plant growth media to Fusarium oxysporum f. sp. dianthi was evaluated in bioassays with carnation (Dianthus cariophyllus) cv. Medea. These media were: (1) grape marc compost, (2) cork compost, (3) olive oil husk + cotton gin trash composted and mixed with rice husk, (4) spent mushroom compost mixed with peat, (5) coir fibre, (6) light peat and (7) vermiculite. In order to look for carnation Fusarium wilt suppressiveness indicators, growth medium pH and ?-glucosidase activity were evaluated. Furthermore, F. oxysporum populations were ...

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Summary There are many active functional compounds in citrus peels, such as flavonoid and phenolic acid. Scientists tried to obtain more bioactive components from citrus peels by various methods. This research investigated the effects of different drying temperatures (50, 60, 70, 80, 90 and 100-C) on changes in the flavonoid, phenolic acid and antioxidative activities of citrus fruit (Citrus sinensis (L.) Osbeck) peels. The total phenolic and flavonoid contents of drying treated orange peels were decreased by lower drying temperature (50 and 60-C) and increased by higher drying temperature (70, 80, 90 and 100-C). Amounts of phenolic compounds in the 100-C treated sample extract were significantly higher than the amounts in the samples heated at other temperatures (P-50 values of orange pee...

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Using data collected with the BESII detector at $e^{+}e^{-}$ storage ring Beijing Electron Positron Collider, the measurements of relative branching fractions for seven Cabibbo suppressed hadronic weak decays $D^0 \\to K^- K^+$, $\\pi^+ \\pi^-$, $K^- K^+ \\pi^+ \\pi^-$ and $\\pi^+ \\pi^+ \\pi^- \\pi^-$, $D^+ \\to \\bar{K^0} K^+$, $K^- K^+ \\pi^+$ and $\\pi^- \\pi^+ \\pi^+$ are presented.

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Delusional beliefs are characteristic of psychosis and, of the delusions, the paranoid delusion is the single most common type associated with psychosis. The many years of research focused on neurocognition in schizophrenia, using standardized neurocognitive tests, have failed to find conclusive cognitive deficits in relation to positive symptoms. However, UK-based psychological research has identified sociocognitive anomalies in relation to paranoid thinking in the form of theory of mind (ToM), causal reasoning and threat-related processing anomalies. Drawing from recent neuroscientific research on the default mode network, this paper asserts that the common theme running through the psychological tests that are sensitive to the cognitive impairment of paranoia is the need to cognitively project the self through time, referred to as mental time travel. Such an understanding of the cognitive roots of paranoid ideation provides a synthesis between psychological and ...

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A brain weight deficit of about 70 mg was induced at doses of approximately 75-mGy and a deficit of 60 mg was induced at 100 mGy. This confirms the effects projected and observed by Wanner and Edwards. Although the data do not demonstrate a clear dose-response relationship between the 75-mGy and 100-mGy groups, the data are statistically consistent with a dose-response effect because of the overlapping confidence intervals. The lack of a statistically significant observation is most likely related to the small difference in doses and the limited numbers of animals examined. There are several factors that can influence the brain weight of guinea pig pups, such as caging and housing conditions, the sex of the animal, and litter size. These should be taken into account for accurate analysis. Dam weight did not appear to have a significant effect. The confirmation of a micrencephalic effect induced x rays at doses of 75-mGy during this late ...

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Attention deficit hyperactivity disorder (ADHD) is known as a psychiatric disorder in childhood associated with dopamine dysregulation. We investigated dopamine transporter (DAT) density in children with ADHD in the present study using {sup 123}I-IPT SPECT and postulated that an alteration in DAT density in the basal ganglia (BG) is responsible for dopaminergic dysfunction in children with ADHD. 9 durg-naive children with ADHD and 6 normal children were included in the study. We performed brain SPECT 2 hours after administration of {sup 123}I-IPT and made both quantitative and qualitative analyses for assessment of specific/nonspecific DAT binding ratio in the BG. We investigated the correlation between the severity scores of ADHD symptoms in children with ADHD assessed with ADHD rating scale and specific/nonspecific DAT binding ratio in the BG. Drug-naive children with ADHD showed a significantly incresed specific/nonspecific DAT binding ratio in the BG compared ...

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Ewing's sarcoma is the most common malignant bone tumour occurring in children and adolescents and exists in two different clinico pathological entities: osseous Ewing's sarcoma (OES) and extraosseous Ewing's sarcoma (EES). Five cases of primary epidural EES are described, which presented with non-specific symptoms leading to a long diagnostic delay. The median age at diagnosis was 22 years (range 13-36 years). The median diagnostic delay was 3 months. All patients had one or more neurological deficits. All underwent surgical exploration with a laminectomy and partial resection followed by adjuvant radiotherapy to a dose of 46-50 Gy and chemotherapy with VAC (vincristine, adriamycin and cyclophosphamide) alternating with ICE (ifosphamide, cisplatin and etoposide) for at least six cycles. The mean follow-up period is 21.2 months (range 11-32 months). Four of the five patients achieved a complete remission and are disease free at the time of writing this report. Two ...

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Short synthetic single-stranded oligodeoxyribonucleotides (ssODNs) can be used to introduce subtle modifications into the genome of mouse embryonic stem cells (ESCs). We have previously shown that effective application of ssODN-mediated gene targeting in ESC requires (transient) suppression of DNA mismatch repair (MMR). However, whereas transient down-regulation of the mismatch recognition protein MSH2 allowed substitution of 3 or 4 nucleotides, 1 or 2 nucleotide substitutions were still suppressed. We now demonstrate that single- or dinucleotide substitution can effectively be achieved by transient down-regulation of the downstream MMR protein MLH1. By exploiting highly specific real-time PCR, we demonstrate the feasibility of substituting a single basepair in a non-selectable gene. Howev...

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Serum growth hormone (GH) was suppressed in female rats bearing mammary tumors induced by 7, 12, dimethylbenz(a)anthracene (DMBA) or N-nitrosomethylurea(NMU). Serum GH was suppressed due to treatment with a human GH analog produced by the plerocercoid stage of the tapeworm Spirometra mansonoides. Rats treated with plerocercoid growth factor (PGF) via plerocercoid infection had accelerated growth rates despite marked reductions in GH levels. Approximately two-thirds of the mammary tumors induced by either DMBA or NMU regressed during three weeks of exposure to PGF while most of the control tumors continued to grow. The data support an important regulatory role for GH in growth of mammary tumors in rats. PMID:3019224

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Mycoplasma ovipneumoniae is associated with chronic non-progressive pneumonia of sheep and goats. As with many other mycoplasmas involved in animal diseases, protective immune responses have not been achieved with vaccines, even though antibody responses can be obtained. This study focuses on characterizing the interaction of M. ovipneumoniae with ovine PBMC using carboxy-fluorescein-succinimidyl-ester (CFSE) loading and flow cytometry to measure lymphoid cell division. M. ovipneumoniae induced a strong in vitro polyclonal suppression of CD4^+, CD8^+, and B blood lymphocyte subsets. The suppressive activity could be destroyed by heating to 60^oC, and partially impaired by formalin and binary ethyleneimine treatment that abolished its viability. The activity resided on the surface-exposed m...

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AbstractThe tick-borne protozoan parasite Theileria annulata causes a debilitating disease of cattle called Tropical Theileriosis. The parasite predominantly invades...Full Text Available

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Behavioral detection of a low-frequency (40 Hz) vibratory dipole at source distances of 1.5–24 cm was measured by classically conditioned respiratory suppression in goldfish (Carassius...Full Text Available

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During the symbiotic interaction between Medicago truncatula and the arbuscular mycorrhizal (AM) fungus Glomus intraradices, an endogenous increase in jasmonic acid...Full Text Available

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A method is reported which permits selective suppression of absorption of radioactive strontium from ingested food material, permitting the calcium to be available to the body. Studies were carried...Full Text Available

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That regulatory T cells (Tregs) have a crucial role in controlling allergic diseases such as asthma is now undisputed. The cytokines most commonly implicated in Treg-mediated suppression of...Full Text Available

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BackgroundGlucocorticoids down-regulate cytokine synthesis and suppress inflammatory responses. The glucocorticoid receptor (GR) antagonist RU486 may exacerbate the inflammatory...Full Text Available

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Multiple stimuli present in the visual field at the same time compete for neural representation by mutually suppressing their evoked activity throughout visual cortex, providing a neural correlate...Full Text Available

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Suppressed IL-12 production and maladaptive immune activation, both of which are ameliorated by successful highly active antiretroviral therapy (HAART), are thought to play important roles in the immunopathogenesis...Full Text Available

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BackgroundThe mammalian FoxO transcription factors function to regulate diverse physiological processes. Emerging evidence that both BDNF and lithium suppress FoxO...Full Text Available

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Fault current limiters (FCLs) are devices for to suppress current in electric power system. The FCL is extensively expected to suppress fault current, particularly required for trunk power systems heavily connected high-voltage transmission lines, such as 500 kV class power system. For this reason, FCLs based on various principles of operation have been developed. Most of the FCLs under development which employ superconductors are based on the quenching phenomenon peculiar to the superconducting state, that is, making use of a rapid transition to normal conducting state, an electrical resistance appears, and this resistance is used to suppress fault currents. However, this elevation of resistance, although increasing the fault current suppression effect, also tend to raise the overvoltage occurring FCL, the ascertainment of the overvoltage is important as regards the protection of the FCL as well as ...

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BWRs are so designed that the exhaust steam from main steam safety relief valves is led to pressure suppression pools, and the steam is condensed in pool water, but at this time, dynamic load seems to arise in the pool water. In Tokai No. 2 Power Station, a Mark-2 containment vessel was adopted to improve the reliability as much as possible and to obtain the design with margin. In this report, the result of actual machine test in Tokai No. 2 Power Station and the method of reducing the load are described. When a relief valve works, the discharge of water in exhaust pipes into a suppression pool, the exhaust of air in exhaust pipes and repeated expansion and contraction of bubbles in pool water, and the exhaust of steam and condensation occur. As for the construction of the suppression pool in Tokai No. 2 Power Station, cross-shaped quencher and the structure with jet deflector were installed. The test plan and the test ...

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RC-12 [1,2-dimethoxy-4-(bis-diethylaminoethyl)-amino-5-bromobenzene] was evaluated for prophylactic, radical curative, and suppressive activities against infections with Plasmodium cynomolgi and subacute...Full Text Available

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The “cloverleaf” base-pairing pattern was established as the structural paradigm of active tRNA species some 30 years ago. Nevertheless, this pattern does not accommodate the folding...Full Text Available

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Low concentrations of sugars altered the sensitivity of seed germination to inhibition by exogenous abscisic acid (ABA). Germination of wild-type and ABA-insensitive (abi) Arabidopsis...Full Text Available

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A cDNA encoding a cytochrome P450 enzyme was isolated from a cDNA library of the corpora allata (CA) from reproductively active Diploptera punctata cockroaches. This P450 from the endocrine...Full Text Available

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Continuum events represent an eminent source of background in any e+e- experiment. As these have a higher branching ratio than BB-bar events (at BaBar this ratio is estimated to about 3.5) or ?+?- events, efficient continuum background suppression is essential in many analyses. Using Artificial Neural Networks and the Nearest Neighbor Method we developed several selectors which, based only on the global event shape variables, efficiently tag BB-bar events and ?+?- events against the continuum background. These selectors could then be combined with the channel specific information in various types of analyses. The study was done using a parametric Monte Carlo.

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Difficulty in recalling the names of people is very common in the early stages of Alzheimer's disease and in mild cognitive impairment (MCI). However, it is not known whether the difficulty in naming people in MCI reflects problems associated with lexical access or with semantic access. The aims of the present study were to investigate semantic and phonological access to proper names by use of a Tip-of-the-tongue (TOT) task in individuals with multidomain amnestic MCI, individuals with amnestic MCI, and healthy controls, as well as to study the relationships between TOT production and performance in a free recall verbal memory test. In the individuals with multidomain amnestic MCI, the main process affected was phonological access; failures in phonological access were related to deficits i...

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A promising drug target currently under investigation to improve cognitive deficits in neuropsychiatric and neurological disorders is the neuronal nicotinic alpha7 acetylcholine receptor (a7nAChR). Improving cognitive impairments in diseases such as Alzheimer's (AD) and schizophrenia remains a large unmet medical need, and the a7nAChR has many properties that make it an attractive therapeutic target. The a7nAChR is a ligand gated ion channel that has particularly high permeability to Ca^2^+ and is expressed in key brain regions involved in cognitive processes (e.g., hippocampus). The a7nAChRs are localized both pre-synaptically, where they can regulate neurotransmitter release, and post-synaptically where they can activate intracellular signaling cascades and influence downstream processes...

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We present a proposal for a combined ICARUS & NOE general purpose detector, to be installed in Hall B of the Gran Sasso Laboratory.The main scientific goal is the one of elucidating in a comprehensive way the pattern of neutrino $9 masses and mixings, following both (1) the S-KAM results and (2) the predictions on atmospheric neutrinos of the large solution of the Solar Neutrinos deficit. To achieve these goals, the experimental method is based upon the $9 complementary and simultaneous detection of CERN beam (CNGS) and cosmic ray (CR) events. This is made possible because of the complete isotropy of the detection technique. For the currently allowed values of the S-KAM results, both $9 CNGS and cosmic ray data will give independent measurements and provide a precise $(sin^{2}2\\theta; \\Delta m^{2})$ determination rather than a wide band of allowed values. Since we can observe and unambiguously identify $9 $\

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Tata Electric Companies (TEC) are engaged in the generation of hydro and thermal energy. TEC, to minimise backing down of its thermal units in off peak hours and also to at least partially meet the growing deficit in the supply during peak hours is moving to install pumped storage plants (PSPs) utilising off-peak surplus energy for pumping the water from lower pond to the upper pond for subsequent utilisation for power generation during peak hours. In view of some of the infra structural facilities such as storage ponds, water conductor system, transmission lines, etc. being already available, at the existing hydro power stations owned by TEC, the pumped storage units are being proposed within the environs of existing hydro stations, i.e. a 150 MW pumped storage unit at Bhira and a 90 MW pumped storage unit at Bhivpuri. The projects are described and cost estimates is given. (author). 2 figs.

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Background In scientific literature, when the consequences of illness are discussed, one finds that the deficit perspective is prevailing: Illness as the cause for loss of abilities and a loss of contentment. On the other hand, particularly with creative people, an increase of creativity can be observed, following a confrontation with and having endured a period of illness. When one considers the occurrence of illness retrospectively in a biographical context, one may find often a biographical standstill. Although illness and disease are considered as a collapse, one may observe also psycho-spiritual maturation processes during the confrontation with illness. In several cases illness can thus result in personality maturation and a higher level of psychological health. Aims Despite of the f...

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The environmental impact caused by local people (ecological footprint of consumption, EFc) and the actual environmental impact that the ecosystem burdens (ecological footprint of production, EFp) in West Jilin Province, Northeast China from 1986 to 2006 were evaluated by using ecological footprint (EF) method. And the major driving forces of EFc and EFp were analyzed by STIRPAT model. Both EFc and EFp showed increasing trends in 1986?2006, accompanied by decreasing ecological deficits but expanding ecological overshoots. Population (P), GDP per capita (A 1), quadratic term of GDP per capita (A 2), urbanization (T a1), and quadratic term of urbanization (T a2) were important influencing factors of EFc, among which T a2 and T a1 were the most dominate driving forces of EFc. A 1, A 2 and T a2...

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ObjectiveInjury is the leading cause of death among American youth, killing more 11-year-olds than all other causes combined. Children with symptoms of externalizing behavior disorders such as attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD) may have increased risk. Our aims were to determine: (1) whether increasing symptoms of ADHD and CD associate positively with injuries among a community sample of fifth graders; and (2) whether symptoms of ADHD and CD have a multiplicative rather than additive association with injuries among the sample. MethodsData were collected from 4745 fifth graders and their primary caregivers participating in Healthy Passages, a multisite, community-based study of pediatric health risk behaviors and health outcomes. The primary outcome wa...

British Library Electronic Table of Contents (United Kingdom)

Abstract Large areas of the southern European countries possess a Mediterranean climate, which influences soil properties, land use, fertilizer application practices and pathways of phosphorus (P) loss from agricultural soils. On average, inputs of fertilizer P exceed P exports from the agricultural areas in these countries; however, large differences in P surplus/deficit and soil P test values exist among regions. Losses of P in drainage water are modest except in some irrigated areas and in those regions where intensive animal production is concentrated. Losses of P in runoff water, whether as dissolved reactive or particulate P, can be substantial as a result of the significance of erosive processes under the land uses typical of the Mediterranean region, where extreme rainfall events c...

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Mullin BC, Harvey AG, Hinshaw SP. A preliminary study of sleep in adolescents with bipolar disorder, ADHD, and non-patient controls.-Bipolar Disord 2011: 13: 425-432. 2011 The Authors.-Journal compilation 2011 John Wiley & Sons A/S. Objectives:- To compare the sleep of adolescents with bipolar disorder (BD) to groups of adolescents with attention-deficit hyperactivity disorder-combined type (ADHD-C) and those without psychopathology. Methods:- A sample of 13 adolescents diagnosed with BD who were not in the midst of a mood episode, 14 adolescents with ADHD-C, and 21 healthy controls, all between the ages of 11 and 17 years served as participants. They were psychiatrically evaluated using a structured diagnostic interview and completed four nights of in-home sleep monitoring using actigraph...

Science.gov (United States)

Somatogenic hormones play an important role in regulation of receptors for prolactin (PRL) and estrogen. Plerocercoids of the tapeworm, S. mansonoides produce a factor which mimics some, but not all of the actions reported for GH. Intact female rats were subjected to a constant infusion of plerocercoid growth factor (PGF) via a subcutaneous infection for two weeks to determine if PGF influences receptors for PRL, GH or estradiol. The rate of weight gain in the PGF-treated rats was accelerated in spite of a marked reduction in serum GH. Partially-purified PGF specifically displaced [125I]hGH from rat liver receptors but microsomes prepared from rats treated with PGF specifically bound significantly less [125I]hGH than microsomes from control rats. The reduction in [125I]hGH binding was not due to occupancy or to a change in affinity but to a suppression in receptor concentration. Scatchard analysis of [3H]estradiol binding in rat liver cytosols shows a 50% reduction ...

Energy Technology Data Exchange (ETDEWEB)

Cell extracts of the thermophile Clostridium thermohydrosulfuricum catalyzed the phosphorylation by (..gamma..-/sup 32/P)ATP of several endogenous proteins with M/sub r/s between 13,000 and 100,000. Serine and tyrosine were the main acceptors. Distinct substrate proteins were found in the soluble (e.g., proteins p66, p63, and p53 of M/sub r/s 66,000, 63,000, and 53,000, respectively) and particulate (p76 and p30) fractions, both of which contained protein kinase and phosphatase activity. The soluble fraction suppressed the phosphorylation of particulate proteins and contained a protein kinase inhibitor. Phosphorylation of p53 was promoted by 10..mu..M fructose 1,6-bisphosphate or glucose 1,6-bisphosphate and suppressed by hexose monophosphates, whereas p30 and p13 were suppressed by 5 ..mu..M brain (but not spinach) calmodulin. Polyamines, including the odd polyamines characteristic of thermophiles, modulated the labeling ...

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Recent work has indicated that the suppression of boron transient enhanced diffusion (TED) in carbon-rich Si is caused by nonequilibrium Si point defect concentrations, specifically the undersaturation of Si self-interstitials, that result from the coupled out-diffusion of carbon interstitials via the kick-out and Frank--Turnbull reactions. This study of boron TED reduction in Si{sub 1-x-y}Ge{sub x}C{sub y} during 750{sup o}C inert anneals has revealed that the use of an additional reaction that further reduces the Si self-interstitial concentration is necessary to describe accurately the time evolved diffusion behavior of boron. In this article, we present a comprehensive model which includes {l_brace}311{r_brace} defects, boron-interstitial clusters, a carbon kick-out reaction, a carbon Frank--Turnbull reaction, and a carbon interstitial-carbon substitutional (C{sub i}C{sub s}) pairing reaction that successfully simulates carbon suppression ...

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An analysis was made on corrosion suppression mechanism of glycoletherdiaminetetraacetic acid (GEDTA) film made from GEDTA on stainless steel, and its corrosion inhibition effect. Results of analysis using IR spectrum, IR-ATR spectrum, {sup 1} HNMR spectrum, and ESCA spectrum indicated the deposition of the GEDTA film is a chemical deposition. In polarization tests at pH = 5 and 7, both polarization curves shifted to the constant current density side, showing suppression effect in reactions at both pH. When the corrosion environment is made severer, such as to pH = 2 and 4, the corrosion suppression effect of GEDTA became more distinctive. A ferroxyl test identified very little difference between untreated and treated materials. In a chemical pitting test, because oxidant and corrosive anion coexist in the test solution, and GEDTA is stable against corrosive anion Cl {sup {minus}}, the film is unstable against the oxidant. ...

International Nuclear Information System (INIS)

In this paper author deals with the regulation of electricity prices in the Slovak Republic. Author contests the social policy of the government through doped prices of electricity. Two thirds of electricity is generated in nuclear power plants in Slovakia. Hence, it is necessary to focus on the solution of problem of nuclear waste. In 2004 Ministry of Economy stated, that the deficit in nuclear fund, from which the country have to fully cover the costs of liquidation and final disposal of nuclear waste, is estimated in the amount of around 89 billion Slovak crowns (? 3.7 billion $). From it, so called historical deficit, which originated because of late foundation of fund, represents officially 15 billion Slovak crowns (? 0.62 billion $). In Slovakia exists the real risk, that by maintenance of present state by creation and draw of the fund, it will be possible to ensure only 39 per cent of financial sources necessary for full financial ...

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Attention deficit hyperactivity disorder (ADHD) has been known as psychiatric disorder in childhood associated with dopamine dysregulation. In present study, we investigated changes in dopamine transporter (DAT) density of the basal ganglias using I-123 N-(3-iodopropen-2-yl) -2-carbomethoxy-3beta-(4-chlorphenyl) tropane (I-123 IPT) SPECT in children with ADHD before and after methylphenidate treatment. Nine drug-naive children with ADHD and seven normal children were included in the study. We performed brain SPECT two hours after the intravenous administration of I-123 IPT and made both quantitative and qualitative analyses using the obtained SPECT data, which were reconstructed for the assessment of specific/nonspecific DAT binding ratios in the basal ganglia. All children with ADHD reperformed (123I)IPT SPECT after treatment with methylphenidate (0.7mg/kg/d) during about 8 weeks. SPECT data reconstructed for the assessment of specific/nonspecific DAT binding ...

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Involvement of the dopaminergic system has been suggested in patients suffering from attention deficit hyperactivity disorder (ADHD) since the symptoms can be successfully treated with methylphenidate, a potent blocker of the dopamine transporter (DAT). This study reports the findings on the status of the DAT in adults with ADHD before and after commencement of treatment with methylphenidate, as measured using [{sup 99m}Tc]TRODAT-1. Seventeen patients (seven males, ten females, aged 21-64 years, mean 38 years) were examined before and after the initiation of methylphenidate treatment (3 x 5 mg/day). All subjects were injected with 800 MBq [{sup 99m}Tc]TRODAT-1 and imaged 3 h p.i. Single-photon emission tomography (SPET) scans were acquired using a triple-headed gamma camera. For semi-quantitative evaluation of the DAT, transverse slices corrected for attenuation were used to calculate specific binding in the striatum, with the cerebellum used as background ...

International Nuclear Information System (INIS)

The effect of in situ photoexcitation during boron ion implantation on subsequent transient enhanced B diffusion in Si has been investigated. Photoexcitation using a mercury arc lamp was performed during B"+ implantation at 35 keV for a dose of 5x10"1"4 cm"-"2 at 177 K. A reduction in the electrical activation dip, i.e., reverse annealing effect, in the temperature range 550--700 degree C was observed. Also, the transient enhanced diffusion of B, measured using SIMS following 800 degree C, 30 min annealing, was suppressed. Both effects demonstrate that the creation of self-interstitials during the implantation process is significantly reduced. copyright 1995 American Institute of Physics.

International Nuclear Information System (INIS)

The magnetic ordering temperature of some rare-earth-based heavy-fermion compounds is strongly pressure dependent and can be completely suppressed at a critical pressure, p_c, making way for novel correlated electron states close to this quantum critical point. We have studied the clean heavy-fermion antiferromagnets CePd_2Si_2 and CeIn_3 in a series of resistivity measurements at high pressures up to 3.2 GPa and down to temperatures in the mK region. In both materials, superconductivity appears in a small window of a few tenths of a GPa on either side of p_c. We present detailed measurements of the superconducting and magnetic temperature-pressure phase diagram, which indicate that superconductivity in these materials is enhanced, rather than suppressed, by the closeness to magnetic order. (author)

British Library Electronic Table of Contents (United Kingdom)

Phospholipase D (PLD) has been recognized as a regulator of cell proliferation and tumorigenesis, but little is known about the molecules regulating PLD expression. Thus, the identification of small molecules inhibiting PLD expression would be an important advance in PLD-mediated physiology. Quercetin, a ubiquitous bioactive flavonoid, is known to inhibit proliferation and induce apoptosis in a variety of cancer cells. In the present study, we examined the effect of quercetin on the expression of PLD in U87 glioma cells. Quercetin significantly suppressed the expression of PLD1 at the transcriptional level. Moreover, quercetin abolished the protein expression of PLD1 in a time and dose-dependent manner, as well as inhibited PLD activity. Quercetin suppressed NFkB-induced PLD1 expression vi...

International Nuclear Information System (INIS)

Object: To suppress a quantity of impurities in a coolant fed into a reactor vessel. Structure: The concentration of oxygen in a coolant flowing from a condensation desalting instrument into a feed and condensation piping is measured by an oxygen-concentration detector to feed its signal to an adjusting instrument. A degree of opening of an oxygen flow control valve to maintain the concentration of oxygen in the cooling water flowing within the pipe in the range from about 10 to about 200 ppb. Also, the concentration of oxygen in the cooling water fed to the desalting instrument is maintained at a level less than 2 ppb. Thereby, the total amount of iron flown into the vessel can be suppressed to a fine amount such as less than about 1 ppb. (Kawakami, Y.).

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The present invention concerns a high thermal load heat receiving plate such as a divertor plate of a thermonuclear device. The high thermal load heat receiving plate of the present invention has a cooling performance capable of suppressing the temperature of an armour tile to less than a threshold value of the material against high thermal loads applied from plasmas. Spiral polygonal pipes are inserted in cooling pipes at a portion receiving high thermal loads in the high temperature load heat receiving plate of the present invention. Both ends of the polygonal pipes are sealed by lids. An area of the flow channel in the cooling pipes is thus reduced. Heat conductivity on the cooling surface of the cooling pipes is increased in the high thermal load heat receiving plate having such a structure. Accordingly, temperature elevation of the armour tile can be suppressed. (I.S.).

International Nuclear Information System (INIS)

Purpose: To obtain stabilized operation by preventing over heat in emergency cooling pumps upon accidents of flow regulators. Constitution: A pressure suppression chamber pool and a pressure vessel are communicated to each other with a pipeway and the water in the suppression pool is charged by a charging pump to the pipeway. The pipeway is interposed with an emergency cooling pump so as to feed water in the pipeway to the pressure vessel and a water source and the emergency cooling pumps are connected by way of a closed pipeway. Further, the closed pipeway and the pipeway interposed with the charging pump are communicated to each other by way of a connecting pipeway, to which are interposed an instrument for detecting the increase in the temperature of the emergency cooling pumps due to abnormality in the closed pipe (such as troubles in flow regulators) and outputting control signals and an electrically actuated valve controlled by a control ...

International Nuclear Information System (INIS)

The activity of tyrosine aminotransferase (TAT) in the liver of mice subjected simultaneously to ionizing radiation and to local inflammatory process showed in the first 24 hours of the experiment statistically significant changes resulting from summation of the harmful effects of both factors. In the second 24-hour period an evident tendency was observed for return of a normal circadian rhythm of the enzyme. This points to presence of an endogenous mechanism of suppression of the manifestations of significant desynchronization of the circadian rhythm. The paper contains also a trial of mathematical analysis of changes in TAT activity in the circadian rhythm, a description and analysis or the suppression process, qualitative and quantitative determination of the phenomenon of cumulation of the effects of powerful stress factors acting on the animal organism. The obtained results were compared with the results of investigations of TAT activity ...

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SIMS measurements revealed that high energy boron-implantation causes transient enhanced diffusion (TED) of a shallow dopant profile due to Si interstitials even for a relatively low dose of {approximately}2E13cm{sup {minus}2}. By systematic analysis, it is found that this anomalous diffusion is most significant in 700--800 C annealing, and it takes place in the initial stage (less than 30 sec for 800 C) of annealing. Moreover, this anomalous diffusion is more considerable than the enhanced diffusion during oxidation (OED) in practical device fabrication processes. It is found that rapid thermal annealing (RTA) at 1,000--1,100 C is effective for suppressing the transient enhanced diffusion and realizing a shallow channel profile for deep sub-micron devices.

British Library Electronic Table of Contents (United Kingdom)

Antisense- or RNAi-mediated suppression of the biosynthesis of nutritionally inferior storage proteins is a promising strategy for improving the amino acid profile of seeds. However, the potential pleiotropic effects of this on interconnected pathways and the agronomic quality traits need to be addressed. In the current study, a transcriptomic analysis of an antisense C-hordein line of barley was performed, using a grain-specific cDNA array. The C-hordein antisense line is characterized by marked changes in storage protein and amino acid profiles, while the seed weight is within the normal range and no external morphological irregularities were observed. The results of the transcriptome analysis showed excellent correlation with data on changes in the relative proportions of storage protei...

UK PubMed Central (United Kingdom)

Although caloric restriction (CR) has been shown to increase lifespan in various animal models, the mechanisms underlying this phenomenon have not yet been revealed. We developed an in vitro...Full Text Available

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In the present study, the immunomodulatory effect of {beta}-endorphin ({beta}-E) and shorter pro-opiomelancortin (POMC) fragments was evaluated by assessing their influence on respiratory burst in human polymorphonuclear leukocytes (PMN). The effect of the peptides on phorbol myristate acetate (PMA)-stimulated production of reactive oxygen metabolites was measured in a lucigenin-enhanced chemiluminescence (CL) assay. Both POMC peptides with opiate-like activity and their non-opioid derivatives were tested. With the exception of {alpha}-E, PMA-stimulated respiratory burst was suppressed by all POMC fragments tested. A U-shaped dose-response relation was observed. Doses lower than 10{sup {minus}17}M and higher than 10{sup {minus}8}M were without effect. {beta}-E and dT{beta}E both suppressed PMA-induced oxidative burst in human PMN at physiological concentrations. {gamma}-E and dT{gamma}E proved to be less potent inhibitors, reaching maximal ...

UK PubMed Central (United Kingdom)

Elite suppressors or controllers (ES) are HIV-1 infected patients who maintain undetectable viral loads without treatment. While HLA-B*57-positive ES are usually infected with virus that is unmutated...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This book presents papers on internal combustion engines. Topics considered include the influence of partial suppression of heat rejection on performance and emissions, duothermic combustion, turbochargers made of sintered silicon nitrides, heat flux, low heat rejection engines, exhaust energy recovery, combustion chamber insulation, computerized simulation, heat transfer, friction, hoop stress effects, and bonding ceramics and metals.

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Transverse form factors have been extracted for the low-lying neutron hole (particle) states of /sup 207/Pb from inelastic-electron-scattering data. A systematic, multipolarity-and momentum-transfer-independent quenching of approx.55% in the transverse amplitude is observed when compared with single particle predictions for both electric and magnetic transitions. The magnitude of the observed effect is not readily explained by our present theoretical understanding of this nucleus.

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At DORIS II/HASYLAB a vertical beam position control system is in regular operation. It controls the position and angle of a photon beam simultaneously, and can stabilize beam movements up to frequencies of 0.1 Hz. To suppress beam vibrations up to 50 Hz and above, a prototype beam stabilization system for these frequencies was built and tested successfully. The present beam oscillations at the HASYLAB beamlines are explained, the quality of the beam position control system and the results of the prototype test are presented.

UK PubMed Central (United Kingdom)

BackgroundHIV infection causes a qualitative and quantitative loss of CD4⁺ T cell immunity. The institution of anti-retroviral therapy (ART) restores CD4⁺ T...Full Text Available

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The relativistic motion of an electron is numerically analyzed in a tokamak having macroscopic magnetic turbulence. Stochasticity induced by the relativistic motion overwhelms the phase averaging effect, which provides a tokamak with an effective loss mechanism for the avoidance/suppression of runaway electron generation at a major disruption. On the other hand, electrons in the KAM (Kolmogorov-Arnold-Moser) region will be observed as a runaway snake. (author)

Science.gov (United States)

It is suggested that the large reduction of the superconducting transition temperature Tc due to defects observed experimentally in some A-15 compounds is caused by smearing of a high peak in the density of states at the Fermi level. The influence of defects on other physical properties (the magnetic susceptibility ?, the elastic modulus Cs, the structural transformation temperature Tm and the electrical resistivity ?) is also discussed from the same point of view. We expect the anomalous temperature dependence of ?, Cs and ? will be suppressed by defects.

UK PubMed Central (United Kingdom)

Adenovirus vaccine vectors derived from rare human serotypes have been shown to be less potent than serotype 5 (Ad5) at inducing immune responses to encoded antigens. To identify highly immunogenic...Full Text Available

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An animated test is made for mice with malignant tumors irradiated by a self-made millimetre wave radiator for medical purpose. It is observed that S-180 sarcomas in mice after irradiation has been distinctly suppressed. And remarkable effects are shown through a lot of clinical practices on peptic ulcer, skin-deep ulcer, acute and chromic soft tissue injuries etc.

International Nuclear Information System (INIS)

In this article carbon co-implantation and step-by-step thermal treatments of shallow p"+-n-junctions formation were used with the purpose of extended defect suppression and reduction of boron transient enhanced diffusion. A substantial improvement of the structural and electrical parameters of shallow p"+-n-junctions has been achieved by using the additional carbon implantation and step-by-step thermal treatments. (authors)

UK PubMed Central (United Kingdom)

G protein-coupled receptors (GPCRs) are known to modulate intracellular effectors involved in cardiac function. We recently reported homocysteine (Hcy)-induced ERK-phosphorylation was suppressed...Full Text Available

UK PubMed Central (United Kingdom)

Type II diabetes mellitus (T2DM) is often accompanied by non-alcoholic steatohepatitis (NASH) and associated with hypercholesterolemia, i.e. increased levels of plasma low-density...Full Text Available

International Nuclear Information System (INIS)

Apoptosis, or programmed cell death (PCD), is a fundamental process that protects organismal integrity. In earlier work, we demonstrated that over-expression of either of two anti-apoptotic members of the BCL-2 family (BCL-2 or BCL-X L could elevate the frequency of radiation-induced mutations at the autosomal TK1 locus in human TK6 lymphoblasts that express wild-type TP53. Ectopic expression of BCL-X L also elevated the frequencies of double-strand break-induced gene conversion. The purpose of this study is to determine if BCL-2 family proteins promote radiation mutagenesis indirectly through their suppression of PCD, or whether the 'pro-mutagenic' function of these proteins can be separated from their anti-apoptotic function. We developed stable transfectants of TK6 cells that express a mutated form of BCL-X L with a single amino acid substitution in the BH1 domain that is known to interfere with the ability to suppress PCD (BCL-X L ...

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A new technique is described in this paper for a general active radio frequency (RF) filter trap that can be used for suppressing noise or interference on high voltage (HV) transmission lines. The technique exploits the Miller effect of an RF amplifier in conjunction with a special sensing circuit, and is potentially far more economical to implement than conventional techniques that use passive HV filter components.

UK PubMed Central (United Kingdom)

Tea catechin is one of the compounds that are closely related to obesity and insulin sensitivity. In order to determine the effect of catechin on adipocyte differentiation, we treated 3T3-L1 preadipocytes...Full Text Available

Science.gov (United States)

The usefulness of psychoanalysis to psychosomatic medicine has been limited by the longstanding assumption that the psychological disorder in psychosomatic patients resembles the conflict-based psychopathology that Freud identified in psychoneurotic patients. Recent investigations of the alexithymia construct, and the discovery that social relationships can influence health over the entire life span, have challenged this assumption and created an opportunity for a new and active involvement of psychoanalysis with psychosomatic medicine. In this contribution, I offer a synthesis of contemporary psychoanalytic observations and theories with concepts and research findings from developmental psychology, developmental biology, and the biomedical sciences. The proposed synthesis is consistent with the view that living organisms are self-regulating cybernetic systems; it also extends an evolving new psychosomatic model that conceptualizes illnesses and diseases as disorders of ...

British Library Electronic Table of Contents (United Kingdom)

Dehydrins, a subfamily of group 2 LEA proteins, are intrinsically unstructured plant proteins that accumulate in the late stages of seed development and in vegetative tissues subjected to water deficit, salinity, low temperature, or abscisic acid treatment. In this study, we isolated and characterized ZmDHN2b, a maize dehydrin gene. The genomic organization of the ZmDHN2b gene and its expression in maize seedlings were analyzed. To investigate the function of ZmDHN2b, we generated transgenic tobacco plants constitutively overexpressing ZmDHN2b. Ectopic expression of ZmDHN2b in tobacco accelerated seed germination and seedling growth at 15?C. Furthermore, ZmDHN2b-overexpressing lines had lower levels of cold-induced malondialdehyde and less electrolyte leakage than wild-type tobacco at 4?C....

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To determine the diagnostic accuracy of iofetamine hydrochloride I 123 (IMP) with single photon emission computed tomography in Alzheimer's disease, we studied 58 patients with AD and 15 age-matched healthy control subjects. We used a qualitative method to assess regional IMP uptake in the entire brain and to rate image data sets as normal or abnormal without knowledge of subjects'clinical classification. The sensitivity and specificity of IMP with single photon emission computed tomography in AD were 88% and 87%, respectively. In 15 patients with mild cognitive deficits (Blessed Dementia Scale score, less than or equal to 10), sensitivity was 80%. With the use of a semiquantitative measure of regional cortical IMP uptake, the parietal lobes were the most functionally impaired in AD and the most strongly associated with the patients' Blessed Dementia Scale scores. These results indicated that IMP with single photon emission computed ...

CERN Document Server

Using electron spin resonance, lattice position and dynamic properties of Mn2+ ions were studied in 0.5 and 2 % manganese doped SrTiO3 ceramics prepared by conventional mixed oxide method. The measurements showed that Mn2+ ions substitute preferably up to 97 % for Sr if the ceramics is prepared with a deficit of Sr ions. Motional narrowing of the Mn2+ ESR spectrum was observed when temperature increases from 120 K to 240-250 K that was explained as a manifestation of off-center position of this ion at the Sr site. From the analysis of the ESR spectra the activation energy Ea = 86 mV and frequency factor 1/?0 ? (2-10)x10^(-14) 1/s for jumping of the impurity between symmetrical off-center positions were determined. Both values are in agreement with those derived previously from dielectric relaxation. This proves the origin of dielectric anomalies in SrTiO3:Mn as those produced by the reorientation dynamics of Mn2+ dipoles.

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Attention deficit disorder (ADHD) is a complex biobehavioral phenotype which affects up to 8% of the general population and often impairs social, academic, and job performance. Its origins are heterogeneous, but a significant genetic component is suggested by family and twin studies. The murine strain, coloboma, displays a spontaneously hyperactive phenotype that is responsive to dextroamphetamine and has been proposed as a genetic model for ADHD. Coloboma is a semi-dominant mutation that is caused by a hemizygous deletion of the SNAP-25 and other genes on mouse chromosome 2q. To test the possibility that the human homolog of the mouse coloboma gene(s) could be responsible for ADHD, we have carried out linkage studies with polymorphic markers in the region syntenic to coloboma (20p11-p12). Five families in which the pattern of inheritance of ADHD appears to be autosomal dominant were studied. Segregation analysis of the traits studied suggested that the best ...

International Nuclear Information System (INIS)

The important role of thyroid hormones in growth and development, maintenance of body temperature, digestion, cardiac function, and normal brain development can be disrupted by environmental contaminants like polychlorinated biphenyls (PCB). Polychlorinated biphenyls are environmental contaminants that are widespread, persistent, lipophilic, and bioaccumulate through food webs, concentrating in adipose tissue. Placental and lactational PCB exposure of offspring causes metabolic and endocrine disruptions including hypothyroxinemia, spatial learning and memory deficits, neurochemical and neurobehavioral alterations, and reproductive problems. Previous studies in our lab using the individual congeners PCB 47 (2,2',4,4'-tetrachlorobiphenyl, ortho-substituted) and PCB 77 (3,3',4,4'-tetrachlorobiphenyl, non-ortho-substituted) have demonstrated alterations in thyroid hormone levels, alterations in brain choline acetyltransferase (ChAT) activity, and spatial learning ...

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This paper describes an outline of solid fuel production process from brown coal and the investigation results of its elemental techniques. Dried coal is produced by this process which consists of a dewatering of crushed brown coal in oil-based solvent, a solid and liquid separation of slurry, and a remained oil recovery by heating. This process is characterized by the higher thermal efficiency compared with usual drying and the restraint of spontaneous combustion of product coal. It was revealed that solid fuel with low moisture, low ash, low sulfur, and suppressed spontaneous combustion property can be produced from Australian brown coal through this process. From the comparison between kerosene and fuel oil A, it was confirmed that the oil content during dewatering was smaller and the oil recovery by heating was easier by using a solvent with lower boiling point. It was also confirmed that the spontaneous combustion property can be ...

International Nuclear Information System (INIS)

The purpose of the present study was to examine the in vitro effects of low-dose cadmium (Cd) on developing cortical cells. The cortical cells removed from fetuses (embryonic day 15) were treated with 10 nM of Cd for 24 h. The effects of Cd on dendritic and synaptic development were immunocytochemically observed with anti-microtubule associated protein-2 (MAP2) and anti-synapsin I antibodies, respectively. Administration of Cd suppressed dendritic as well as synaptic development at 10 nM. By two-dimensional gel electrophoresis and liquid chromatography-tandem mass spectrometric (LC/MS/MS) analysis, we identified three proteins with different expression after Cd-treatment; dihydropyrimidinase-related protein 2 (DRP-2/CRMP-2), 14-3-3-epsillon and calmodulin (CaM). Though the number of identified proteins was small, these proteins are known to be involved in neuronal development. The present study demonstrated the morphological effects as well as affected proteins in ...

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Hydrogenation of carbon monoxide at 101.3 kPa has been studied over a series of ion-exchanged Ru catalysts supported on NaX, NaY, KL, Na mordenite, and HY zeolites. The type of zeolite had pronounced effects on the activity and selectivity of the Ru. The specific activity would appear to be related to the dispersion of reduced ruthenium in the zeolite. Methane selectivity, however, seems to be strongly influenced by the type and concentration of alkali cations remaining in the ion-exchanged zeolite. These cations appear to promote chain growth much as traditional alkali promoters would, though perhaps more indirectly. Due to bifunctional properties of the zeolite-supported catalysts, a significant fraction of C/sub 4/ was in the form of isobutane. Formation of isobutane seems to be related to either the Si/Al ratio in the zeolites or the concentration of the remaining alkali cations, but not to the OH concentration. In addition, H/sub 2/ chemisorption at 25/sup 0/C was increasingly ...

Science.gov (United States)

In a previous study, to identify genes of importance for hepatocellular carcinogenesis, and especially for processes involved in malignant transformation, the authors investigated differences in gene expression between adenomas and carcinomas by DNA microarray. In the present study, the authors investigated AW434047, one of the sequences that was upregulated in carcinomas. The investigation led to the identification of a novel gene, which the authors named hepatocyte malignant transforming factor (HMTF), of unknown function whose expression was increased in hepatocellular carcinomas. Northern blot and in situ hybridization also demonstrated high levels of HMTF in rat hepatocellular carcinoma (HCC) cell lines, lymphocytes in the spleen, colon mucosal epithelia, spermatocytes, and granule cells of the hippocampus. Reduction of HMTF by RNA interference (RNAi) in N1 cells, an HCC cell line, caused suppression of cell proliferation, invasion, and migration. ...

Science.gov (United States)

Low-frequency current noise and current-voltage (I-V) characteristics have been studied in InAs/GaAs self-assembled Quantum Dot Infrared Photodetectors in dark conditions and under illumination, at T = 77K and T = 5K. The noise behavior is consistent with a generation-recombination fluctuation process mainly related to thermally excited charge carriers at T = 77K. At T = 5K the current noise is consistent with a mechanism of fluctuations driven by the electric field, related to tunneling rather than emission-capture of charge carriers from the Quantum Dots. A very effective noise suppression mechanism, related to the tunneling regime, determines a decrease of fluctuation intensity as a function of the voltage. At T = 5K, an interesting behavior is observed in the current-voltage and noise power spectra for some of nominally identical QDIP structures in the presence of irradiation. Some devices indeed exhibit (i) a very high photoresponse and (ii) a 1/f-shaped noise ...

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Pacific Northwest Laboratory (PNL) is investigating the use of a rock armoring blanket (riprap) to mitigate wind and water erosion of an earthen radon suppression cover applied to uranium mill tailings. Because the radon suppression cover and the tailings must remain intact for up to 1000 years or longer, the riprap must withstand natural weathering forces. This report is a review of information on rock weathering and riprap durability. Chemical and physical weathering processes, rock characteristics related to durability, climatic conditions affecting the degree and rate of weathering, and testing procedures used to measure weathering susceptibilities have been reviewed. Sampling and testing techniques, as well as analyses of physical and chemical weathering susceptibilities, are necessary to evaluate rock durability. Many potential riprap materials may not be able to survive 1000 years of weathering. Available techniques for durability ...

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The thermal neutron column of the JRR-2 reactor was remodelled in order to install a medical irradiation facility. The design experience and the cource of this remodelling are presented. At first, the thermal neutron flux was lower than expected, and the expected radiation condition was achieved by the following improvements: (1) removal of graphite from the thermal neutron column to increase the neutron flux, (2) twice increase of bismuth shielding and the shift of its position to improve the shielding effect against gamma ray, (3) application of B{sub 4}C rubber on the both surfaces of the shielding door to suppress the secondary gamma ray generation from the structural materials, (4) LiF tiles are applied on the inner face of the neutron beam exit hole to suppress the secondary gamma ray from the beam exit, and (5) installment a cone-shape polyethylene collimator to relieve the decay of thermal neutron. After the improvements, medical ...

Energy Technology Data Exchange (ETDEWEB)

Pfirsch-Schlueter (P-S) current is an inherent property of a finite pressure toroidal equilibrium of tokamak and stellarator. However, it was pointed out recently (V.D. Pustovitov, Nuclear Fusion 36 (1996) 583) that the P-S current would be suppressed completely if the external vertical field could be adjusted to satisfy the condition {omega}=<{omega}> in an l=3 stellarator. Here {omega}=<B tilde{sup 2}>/B{sub 0}{sup 2}-2{epsilon} cos{theta}, l is a pole number, |B tilde| the vacuum helical magnetic field, B{sub 0} the toroidal field, {epsilon} the inverse aspect ratio, {theta} the poloidal angle and <...> denotes the average over the toroidal angle. An example of such a stellarator equilibrium is presented in this paper. For this stellarator equilibrium, behavior of rotational transform and Boozer magnetic spectrum is clarified when the pressure is increased. Both formation of helical magnetic axis and reduction of ...

International Nuclear Information System (INIS)

For spintronic applications it is important to establish how efficiently spins can be injected from a magnetic material into a non-magnetic material and the distance over which those spins survive. It is thought that spin polarised transport current can be determined by using the suppression of the Andreev reflection between a superconductor and the spin polarised material (Science 282 (1998) 85). Cu/Co bilayers are potentially an ideal test system for such study. In this paper we assess the feasibility of using point contact Andreev reflection spectroscopy to address this problem using a superconducting niobium tip at 4.2 K.

Science.gov (United States)

A previous paper introduced the use of wave digital filters as a basic building block for power system simulation, particularly suitable for real-time applications. This paper stresses the simulation of non-linear and switching elements, emphasizing the advantages of the wave filters implementation. The digital structure is maintained even when non-linear components change their characteristics or power electronic devices switch their states. As a very important by-product, the suppression of numerical oscillations related to the trapezoidal rule is achieved in a rather simple way, with no effects on simulation results.

International Nuclear Information System (INIS)

In the Aqueous Self-Cooled Blanket (ASCB) concept, an aqueous "6Li solution in a metallic structure is used as a shielding-breeding blanket for fusion reactors. The experimental results of this study indicate that the radiolytic gas production in an ASCB will be proportional to the absorbed radiation energy. The observed radiation chemical yields allow the preliminary estimation of the radiolysis effects for a specific ASCB design. Contrary to the theoretical predictions, the use of hydrogen as a cover gas at up to 1 MPa had no measurable effect on the radiolytic gas production. Probably it will thus not be possible to suppress the radiolytic decomposition of a low-pressure ASCB by the addition of hydrogen. Catalytic recombination will be required. (orig.).

Energy Technology Data Exchange (ETDEWEB)

We have studied the signals for a heavy Higgs boson in the processes {gamma}{gamma}{yields}WWWW, and {gamma}{gamma}{yields}WWZZ at a photon linear collider. The results are based on the first complete tree-level calculation for these reactions. We show that, with a forward ``spectator`` W tag, and a central ``spectator`` W veto to suppress backgrounds from transverse W, Z production, the invariant mass spectrum of central WW, ZZ pairs is sensitive to Higgs bosons with a mass up to 1 TeV in a 2-TeV linear collider. ((orig.)).

Energy Technology Data Exchange (ETDEWEB)

The vacuum polarization splitting of the M-shell states in muonic hydrogen can have a profound influence on the muonit de-excitation cascade in deuterium and tritium targets. The cascade also shows sensitive dependence on the precise rate of transfer processes between certain excited muonic deuterium and tritium atoms. Recent experimental data, where a much greater population of the (d..mu..) qs state (1/sub 1//sub //sub s/) was found than previously predicted, can be explained if the transfer rates from the (d..mu..) M-shell are assumed to be strongly suppressed.

Energy Technology Data Exchange (ETDEWEB)

Magneto-striction and magnetic form factors in 5f itinerant antiferromagnets UNiGa{sub 5} and UPtGa{sub 5} are studied by means of neutron scattering. Remarkable magneto-striction was observed around T{sub N}, indicating large spin-orbit coupling in the itinerant system. The orbital magnetic moment is found to be strongly suppressed due to the hybridization of uranium 5f with Ga-4p electron.

Energy Technology Data Exchange (ETDEWEB)

A process for the production of transportation fuels from heavy hydrocarbonaceous feedstock is provided comprising a two-stage, close-coupled process, wherein the first stage comprises a hydrothermal zone into which is introduced a mixture comprising a feedstock and metals-impregnated red mud having coke-suppressing and demetalizing activity, and hydrogen; and the second, close-coupled stage comprises a hydrocatalytic zone into which substantially all the effluent from the first stage is directly passed and processed under hydrocatalytic conditions. The preferred metals for impregnation include transition metals, in particular, nickel and molybdenum.

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Differences in the biological disposition and in the effects of the stable lithium isotopes, Li-6 and Li-7, in animals were characterized. A somewhat higher toxicity was associated with WLiCl compared to XLiCl with NLiCl intermediate. All lithium treatments increased water intake and resulted in weight gain. Peak plasma concentration was slightly high for 6Li than 7LiCl suppressed action potential amplitudes during tetanic stimulation more than NaCl when added to Renger solution bathing ganglia.

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Breast cancer progression is characterized by inappropriate cell growth. Normal cells cease growth after a limited number of cell divisions--a process called cellular senescence-while tumor cells may acquire the ability to proliferate indefinitely (immortality). Inappropriate expression of specific oncogenes in a key cellular signaling pathway (Ras, Raf) can promote tumorigenicity in immortal cells, while causing finite lifespan cells to undergo a rapid senescence-like arrest. We have studied when in the course of transformation of cultured human mammary epithelial cells (HMEC), the response to overexpressed oncogenic Raf changes from being tumor-suppressive to tumor enhancing, and what are the molecular underpinnings of this response. Our data indicate: (1) HMEC acquire the ability to maintain growth in the presence of oncogenic Raf not simply as a consequence of overcoming senescence, but as a result of a newly discovered step in the process of immortal ...

International Nuclear Information System (INIS)

The process of miniemulsification allows the generation of small, homogeneous, and stable droplets containing monomer or polymer precursors and magnetite which are then transferred by polymer reactions to the final polymer latexes, keeping their particular identity without serious exchange kinetics involved. It is shown that the miniemulsion process can excellently be used for the formulation of polymer-coated magnetic nanoparticles which can further be used for biomedical applications. The use of high shear, appropriate surfactants, and the addition of a hydrophobe in order to suppress the influence of Ostwald ripening are key factors for the formation of the small and stable droplets in miniemulsion and will be discussed. Two different approaches based on miniemulsion processes for the encapsulation of magnetite into polymer particles will be presented in detail.

Energy Technology Data Exchange (ETDEWEB)

Earlier work carried out on the hydrogen-diesel dual-fuel engine indicates that knock sets in when the inducted hydrogen exceeds about 60% of input energy with a pilot quantity of 30% of full load diesel amount. Some of the findings of an investigation into knock-free performance of a hydrogen-diesel dual-fuel engine with the addition of a diluent-carbon dioxide are presented. The effects of carbon dioxide on the suppression of knocking in the hydrogen-diesel dual-fuel engine and on the improvement in the knock limited power output are described.

CERN Document Server

The existence of light hidden sectors is an exciting possibility that may be tested in the near future. If DM is allowed to decay into such a hidden sector through GUT suppressed operators, it can accommodate the recent cosmic ray observations without over-producing antiprotons or interfering with the attractive features of the thermal WIMP. Models of this kind are simple to construct, generic and evade all astrophysical bounds. We provide tools for constructing such models and present several distinct examples. The light hidden spectrum and DM couplings can be probed in the near future, by measuring astrophysical photon and neutrino fluxes. These indirect signatures are complimentary to the direct production signals, such as lepton jets, predicted by these models.

International Nuclear Information System (INIS)

The asymmetric fingered structure for polysilicon thin-film transistors (AF-TFTs) is analysed in detail by combining experimental characteristics and two-dimensional numerical simulations. This structure allows an effective reduction of the kink effect and off-current, without introducing any additional series resistance. In addition, a substantial improvement in the device stability is also observed when compared to conventional TFT. The AF-TFT characteristics have been explained by considering a two transistor model.

International Nuclear Information System (INIS)

For the purpose of optimizing the process of co-implantation of MeV Si ions to reduce boron transient enhanced diffusion and boron-enhanced diffusion in Si, multiple MeV implantations and annealing at different temperatures have been performed. A slight improvement on the suppression of B diffusion is observed by adding a low temperature annealing step after the MeV implantation. No differences in B diffusion are observed when the Si doses are increased from 1 x 10"1"5 to 1 x 10"1"6 cm"-"2. This dose independent behavior is speculated to be a quasi-steady state of vacancy cluster evaporation.

British Library Electronic Table of Contents (United Kingdom)

For users and manufacturers affected by unwanted electrostatic discharges, the publication of standards concerning the control of such discharges is a great improvement and helps to prevent unwanted electrostatic discharges in potentially explosive atmospheres as well as around electrostatically sensitive devices. There are, for instance, handbook-like documents giving recommendations to help set up effective electrostatic suppressing measures and programs. Another group of standards focuses on certain products and processes and is, thus, more specific. A third group deals with test methods and specifications to help manufacturers develop products that are safe. It also helps in comparisons with other products and thus meets the customer's real needs. To assist manufacturers and customers ...

CERN Document Server

A discrete time control algorithm using the damped least squares is introduced for acceleration and energy exchange controls in nonlinear vibrating systems. It is shown that the damping constant of least squares and sampling time step of the controller must be inversely related to insure that vanishing the time step has little effect on the results. The algorithm is illustrated on two linearly coupled Duffing oscillators near the 1:1 internal resonance. In particular, it is shown that varying the dissipation ratio of one of the two oscillators can significantly suppress the nonlinear beat phenomenon.

Energy Technology Data Exchange (ETDEWEB)

The verification test program on zinc injection applicability to Japanese BWRs was started in 1997. Laboratory tests using high temperature water loops under BWR reactor water conditions are in progress. This paper is an interim report on results obtained so far. Co-58 and Zn-65 were simultaneously used in the Co radioactivity buildup test to evaluate zinc injection suppression effects towards cobalt deposition on pre-oxidized stainless steel. The following results were obtained. The Co deposition was suppressed effectively by Zn injection, even when there was a pre-oxide film. For the test piping that had the pre-oxide film formed under the NWC (normal water chemistry) condition, when soaked under the HWC (hydrogen water chemistry) condition a large amount of Co-58 was taken into a small part of the inner layer. The distribution ratio of Co-58 in the inner layer and outer layer of the oxide film was almost the same for both the pre-oxidized ...

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The authors have found that heat-inactivated serum (57/sup 0/C for 1 hour) from normal chickens reduces the proliferation of mitogen-stimulated chicken and murine splenocytes as well as some transformed mammalian lymphoblastoid cell lines. Greater than a 50% reduction in /sup 3/H-thymidine incorporation was observed when concanavalin A (Con A)-activated chicken splenocytes that were cultured in the presence of 10% autologous or heterologous serum were compared to mitogen-stimulated cells cultured in the absence of serum. Normal chicken serum (10%) also caused greater than 95% suppression of /sup 3/H-thymidine incorporation by bovine (EBL-1 and BL-3) and gibbon ape (MLA 144) transformed lymphoblastoid cell lines. The only cell line tested that was not inhibited by chicken serum was an IL-2-dependent, murine cell line. Chicken serum also inhibited both /sup 3/H-thymidine incorporation and IL-2 synthesis by Con A-activated murine splenocytes. ...

DEFF Research Database (Denmark)

Antisense- or RNAi-mediated suppression of the biosynthesis of nutritionally inferior storage proteins is a promising strategy for improving the amino acid profile of seeds. However, the potential pleiotropic effects of this on interconnected pathways and the agronomic quality traits need to be addressed. In the current study, a transcriptomic analysis of an antisense C-hordein line of barley was performed, using a grain-specific cDNA array. The C-hordein antisense line is characterized by marked changes in storage protein and amino acid profiles, while the seed weight is within the normal range and no external morphological irregularities were observed. The results of the transcriptome analysis showed excellent correlation with data on changes in the relative proportions of storage proteins and amino acid composition. The antisense line had a lower C-hordein level and down-regulated transcript encoding C-hordein. The production of the S-rich B/gamma- and ...

Energy Technology Data Exchange (ETDEWEB)

The aim of this study is three folds: to compare the eight-channel phased-array and standard circularly polarized (CP) head coils in visualiazation of the intracranial vessels, to compare the three-dimentional (3D) time-of-flight (TOF) MR angiography (MRA) techniques, and to define the effects of parallel imaging in 3D TOF MRA. Fifteen healthy volunteers underwent 3D TOF MRA of the intracranial vessels using eight-channel phased-array and CP standard head coils. The following MRA techniques were obtained on each volunteer: (1) conventional 3D TOF MRA with magnetization transfer; (2) 3D TOF MRA with water excitation for background suppression; and (3) low-dose (0.5 ml) gadolinium-enhanced 3D TOF MRA with water excitation. Results are demonstrating that water excitation is a valuable background suppression technique, especially when applied with an eight-channel phased-array head coil. For central and proximal portions of the intracranial ...

International Nuclear Information System (INIS)

In Pakistan, the agricultural sector is the largest water user with 95%, leaving only marginal quantities for households and industry. On one hand, agriculture is a very important sector in Pakistan's economic development, contributing about 23 % to the national GDP -but industry contributes slightly more using only about 2 % of the available water resources. As Pakistan faces a growing problem of water shortage, significant achievements in water conservation have to be materialized, predominantly on the agricultural sector. There is scope for a higher degree of efficiency in water use, as water losses, namely in irrigation, are still rather high. There is another good reason for water conservation in agriculture: Over-irrigation results in rising water tables and increased soil salinity, which has reduced Pakistan's agricultural output during the last 2 decades by nearly 25%. Water conservation measures can be divided into (1) measures which are only applicable under rain-fed ...

International Nuclear Information System (INIS)

During the last years one focus of German PWR safety analysis was boron dilution events with the potential of reactivity transients. Coolant with a low boron concentration could be collected in localized areas of the reactor coolant system e.g. by separation of borated reactor coolant into highly concentrated and diluted fractions (inherent dilution) which can occur during reflux- condenser heat transfer after a small break loss of coolant accident with a limited availability of the emergency core cooling systems. The TUeV NORD SysTec was charged by German supervisory authorities with the assessment of the safety analyses of boron dilution events presented by the utilities. These analyses are based on the simulation of boron dilution and transport processes in conjunction with a number of dedicated experiments. The analyses shall demonstrate that boron dilution events cannot lead to recriticality of the core. Hence the boron concentration at the core inlet has to be determined. TUeV ...

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The neuronal nicotinic acetylcholine receptor {alpha}7 subunit is a member of a family of ligand-gated ion channels, and is the only subunit know to bind {alpha}-bungarotoxin in mammalian brain. {alpha}-Bungarotoxin binding sites are known to be more abundant in the hippocampus of mouse strains that are particularly sensitive to nicotine-induced seizures. The {alpha}7 receptor is highly permeable to calcium, which could suggest a role in synaptic plasticity in the nervous system. Auditory gating deficiency, an abnormal response to a second auditory stimulus, is characteristic of schizophrenia. Mouse strains that exhibit a similar gating deficit have reduced hippocampal expression of the {alpha}7 subunit. We have cloned and sequenced the full length cDNA for the mouse {alpha}7 gene (Acra-7) and characterized its gene structure. The murine {alpha}7 shares amino acid identity of 99% and 93% with the rat and human {alpha}7 subunits, respectively. Using an interspecies ...

International Nuclear Information System (INIS)

Cerebral blood flow (CBF) and cerebrovascular reserve capacity (CRC) were measured by stable xenon computerized tomography (Xe-CT) and acetazolamide test in 15 patients with cerebrovascular disease before and after extracranial-intracranial (EC-IC) bypass surgery for minor stroke, reversible ischemic neurological deficit or transient ischemic attack. All had angiographically shown occlusive lesions of the major arterial trunk. In the present series, global analysis showed that the bypass did not increase the resting rCBF, but did increase the rCRC. We divided the patients into four groups according to the preoperative resting rCBF and rCRC. All 3 patients with normal resting rCBF and reduced rCRC showed postoperative improvement of rCRC. Of 6 patients with reduced CBF and reduced CRC, three had postoperative increase in resting CBF and four had increased CRC. One of two patients with reduced CBF and normal CRC showed only an increase in CRC. We propose that reduced ...

Energy Technology Data Exchange (ETDEWEB)

Resistance to thyroid hormone (RTH) is an autosomal dominant disease caused by mutations in the human thyroid receptor beta gene on chromosome 3. Individuals with RTH have an increased incidence of attention deficit hyperactivity disorder (ADHD). The purpose of this study was to search for developmental brain malformations associated with RTH. Forty-three subjects (20 affected males [AM], 23 affected females [AF]) with resistance to thyroid hormone and 32 unaffected first degree relatives (18 unaffected males [UM], 14 unaffected females [UF]) underwent MRI brain scans with a volumetric acquisition that provided 90 contiguous 2 mm thick sagittal images. Films of six contiguous images beginning at a standard sagittal position lateral to the insula were analyzed by an investigator who was blind with respect to subject characteristics. The presence of extra or missing gyri in the parietal bank of the Sylvian fissure (multimodal association cortex) and multiple Heschl`s ...

Energy Technology Data Exchange (ETDEWEB)

CNG vehicles suffer from an uncontrolled temperature rise of the gas inside the tank during the filling process and heat exchange with the environment leads to variable filling levels. A partly filled tank reduces the range of CNG vehicles and works as a impediment to the spreading of environmentaly more friendly CNG vehicles. The increase of the pressure inside the tank combined with a prolongation of the filling time beyond three minutes can reduce the deficit of the filling process. For economic reasons the time required for refuelling should be as short as possible without the need to operate the filling station with a critical pressure. To meet this target the current technique requires further improvement. (orig.) [Deutsch] Die betriebliche Praxis bei Tankvorgaengen von Erdgasfahrzeugen zeigt, dass waehrend des Tankvorganges die Temperatur des getankten Erdgases im Fahrzeugtank ansteigt. Waehrend und nach Beendigung des Tankvorganges findet ein ...

Energy Technology Data Exchange (ETDEWEB)

The effects of upwind turbine wakes on the performance of a FloWind 17-m VAWT were investigated through a series of field experiments conducted at the FloWind windfarm on Cameron Ridge, Tehachapi, California. The field experiment was conducted within a VAWT array consisting of more than nine VAWTs with separations 3D crosswised by 8D downwind (where D is the turbine diameter) in a staggered configuration. The array is the upwind three rows of VAWTS in a total of six rows that are on top of the Cameron Ridge plateau. The terrain features in the vicinity are reasonably regular, with an upslope of 7 deg on the average; however, several local irregularities are present. The annual hourly averaged wind speed exceeds 8 m/s at the site. The wind field and the power-outputs of nine turbines within the array were measured with wind sensors and power transducers. Nine Gill propeller and 18 Maximum cup anemometers and one direction sensor were mounted on portable and stack-up towers installed ...

International Nuclear Information System (INIS)

Cadmium is a non-essential heavy metal found abundantly in the environment. Children of women exposed to cadmium during pregnancy display lower motor and perceptual abilities. High cadmium body burden in children is also related to impaired intelligence and lowered school achievement. However, little is known about the molecular and cellular basis of developmental neurotoxicity in the sensitive early life stages of animals. In this study, we explore neurological deficits caused by cadmium during early embryonic stages in zebrafish by examining regionalization of the neural tube, pattern formation and cell fate determination, commitment of proneural genes and induction of neurogenesis. We show that cadmium-treated embryos developed a smaller head with unclear boundaries between the brain subdivisions, particularly in the mid-hindbrain region. Embryos display normal anterior to posterior regionalization; however, the commitment of neural progenitor cells was affected ...

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The variation of surface composition and sintering of the binary Pd{sub 7}Ag{sub 3} nanoparticles prepared by chemical reduction were studied. The composition of the as-prepared Pd{sub 7}Ag{sub 3} nanoparticles across the diameter is inhomogeneous due to different reduction potentials of Pd and Ag. Upon heating, Ag will migrate to the surface because of its lower surface energy. Surface modification results in variation of surface composition during the sintering process. Stearic acid acts as a grain growth inhibitor. The migration of Ag to the surface is suppressed and the sintering is retarded. Modification by polyethylene glycol leads to more migration of Ag atoms from the core to the surface. This makes the nanoparticles easier to sinter.

Science.gov (United States)

This paper presents a semi-active vibration control of a scaled two-span bridge structure. Magneto-rheological fluid dampers are utilized as the semi-active energy absorbing deices and a bridge vibration control system is developed. Closed-loop control system based on fuzzy logic is used to suppress the bridge deck motion under random excitations. The sufficient condition for the closed-loop stability of the fuzzy control system is derived from the variable structure system theory. It is demonstrated that this stable fuzzy control system can significantly reduce the relative deck displacement using about 55 percent less power compared to passive-on state, while the absolute deck acceleration is relatively unaffected.

British Library Electronic Table of Contents (United Kingdom)

The seminal work of Stern and his coauthors on integrated control has had a profound and long-lasting effect on the development of IPM programs in western orchard systems. Management systems based solely on pesticides have proven to be unstable, and the success of IPM systems in western orchards has been driven by conservation of natural enemies to control secondary pests, combined with pesticides and mating disruption to suppress the key lepidopteran pests. However, the legislatively mandated changes in pesticide use patterns prompted by the Food Quality Protection Act of 1996 have resulted in an increased instability of pest populations in orchards because of natural enemy destruction. The management system changes have made it necessary to focus efforts on enhancing biological control n...

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The studies using phantoms confirmed that the reduction of electron beam energy and minimization of X-ray contamination could be achieved when electron beam was interposed by an acrylic plate placed 20 cm anterior to a patient. Four patients of mycosis fungoides were treated with 8 MeV electron beam of a linear accelerator at UOEH Hospital from October 1981 to December 1986. Two of them were treated with this technique by placing 2 cm thick acrylic plate anterior to the patients and satisfactory results were obtained. Cutaneous lesions subsided remarkably with the dosage of 2000 cGy given in 2 months. Leucopenia due to bone marrow suppression was mild and the patients tolerated the treatment well.

International Nuclear Information System (INIS)

The production of ozone in a negative corona discharge fed by carbon dioxide with embedded traces of oxygen and water has been studied. The presence of traces of oxygen in both pure and dry CO_2 leads to an increase in nascent ozone concentrations. In contrast, traces of water vapour (0-800 ppm) are shown to rapidly suppress ozone concentrations with the largest decreases being observed at lowest gas pressures in the discharge (300 Torr). The presence of water vapour did not considerably affect the electrical properties of negative dc corona suggesting that a chemical process is responsible for the ozone loss. We have shown that the addition of water up to a concentration of 1500 ppm has only a marginal effect on the processes of ozone formation but the catalytic cycle of ozone destruction involving OH radicals can be the reason for observed decrease in the total ozone concentration with increasing water concentration.

British Library Electronic Table of Contents (United Kingdom)

A stable BSA blocking poly(dimethylsiloxane) (PDMS) microchannel was prepared based on in situ synthesized PDMS-gold nanoparticles composite films. The modified microchip could successfully suppress protein adsorption. The assembly was followed by contact angle, charge-coupled device (CCD) imaging, electroosmotic flow (EOF) measurements and electrophoretic separation methods. Contact angle measurements revealed the coated surface was hydrophilic, water contact angle for coated chips was 45.2^o compared to a water contact angle for native PDMS chips of 88.5^o. The coated microchips exhibited reproducible and stable EOF behavior. With FITC-labeled myoglobin incubation in the coated channel, no fluorescence was observed with CCD image, and the protein exhibited good electrophoretic effect in ...

International Nuclear Information System (INIS)

The forced nonlinear vibration and its stability of a single-degree-of-freedom system with a ball screw type damper which is composed of a ball screw, a flywheel and a flyball governor are discussed theoretically. The results are compared with a linear solution and the experimental results. The effect of vibration isolation of the damper is also discussed. Numerical examples are given for several ratios of the natural frequencies in the primary system to the governor. It is demonstrated that, when the natural frequency ratio is chosen suitably, the damper is effective in suppressing the resonance of the primary system. The amplitude response curve of the primary system is approximately equal to the linear solution except in the vicinities of the natural frequencies of the primary system and the governor, and is stable except in the vicinity of the natural frequency of the governor. (author).

British Library Electronic Table of Contents (United Kingdom)

Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into chondrocytes, osteoblasts, myocytes, adipocytes, and a variety of other cell types. Several studies have been directed toward using MSCs from patients with osteoarthritis (OA) for cartilage repair, not only because these are the ones that will require a source of autologous stem cells if biological repair of cartilage lesions is to be a therapeutic option, but also to further an understanding of stem cell differentiation. Previous studies have shown that a major drawback of current cartilage and intervertebral disc tissue repair is that human MSCs from OA patients express type X collagen (COL X). COL X, a marker of late-stage chondrocyte hypertrophy, is implicated in endochondral ossification. However, those st...

British Library Electronic Table of Contents (United Kingdom)

The X-ray storage phosphor CsBr:Eu2+ in form of needle image plates is believed to be a promising alternative to the granular BaFBr:Eu2+ with regard to PSL yield and spatial resolution. Unfortunately, CsBr:Eu2+ exhibits poor radiation hardness, which is caused by a migration of europium ions initiated by naturally existing defect centers like (Eu2+-VCs)-centers and X-ray generated MEu-centers. It will be shown that the formation of (Eu2+-O2?)-dipoles at the expense of (Eu2+-VCs)-dipoles, incorporated by thermal annealing in O2-containing and humid atmosphere, does not improve the radiation stability. There is, however, a strong improvement in the radiation hardness by codoping of CsBr:Eu2+ with lithium ions, which is accompanied by a complete suppression of the previously observed MEu-cent...

British Library Electronic Table of Contents (United Kingdom)

Immune function is critical in health and disease. The control and regulation of immune reactions is an area of intense investigation that has important implications for allogeneic hematopoietic cell transplantation. Immune reactions are regulated in a number of important ways. Compartmentalization of immune responses and the production of both pro-inflammatory and anti-inflammatory cytokines play a major role. More recently several populations of T cells that regulate immune responses termed regulatory T cells have been identified. This manuscript will focus on CD4^+CD25^+FoxP3^+ natural regulatory T cells (T"r"e"g) and @a@bTCR^+CD4^+NK1.1^+ natural killer T (NK-T) cells which both suppress graft vs host disease but appear to function by distinct mechanisms.

Energy Technology Data Exchange (ETDEWEB)

The concept of the self-focusing plasma lens in various beam-plasma interaction regimes is reviewed. We found that in order for current neutralization to occur, it is only necessary to attain the condition {ital k}{sub {ital p}}{sigma}{sub {ital x}}{approx_gt}1, and not {ital k}{sub {ital p}}{sigma}{sub {ital y}}{approx_gt}1, for flat beams. This helps to substantially reduce the required plasma density for beamstrahlung suppression. We also report on a recent calculation on the detector backgrounds induced by a plasma lens. It is shown that these backgrounds are within the tolerance of all major components in a NLC-like detector. Finally, one other potential application of plasma lens for {gamma}{gamma} colliders is discussed.{copyright}{ital American Institute of Physics.}

International Nuclear Information System (INIS)

The phase diagram of Gdsub(x)Ysub(1-x)Th_4B_4 between the paramagnetic, superconducting and ferromagnetic state is reported. Low temperature dc-magnetization measurements reveal that macroscopic electro-magnetic effects are of minor importance for the suppression of Hsub(2c), which shows a smooth bell-shaped behavior for x >= 0.15 with no indication of an anomaly near Tsub(c2). At low temperature in samples with x >= 0.20 a transition from type II to type I superconductivity seems to occur. The low temperature normal state susceptibility follows a Curie-Weiss law indicating reentrant behavior for x >= 0.10. (orig.).

Science.gov (United States)

Linearly polarized laser radiation accelerates electrons to very high velocities and these electron form a sheath layer on the rear side of thin targets where preferentially protons are accelerated. When mass-limited targets are used, the lateral transport of the absorbed laser energy is reduced and the accelerating field is enhanced. For targets consisting of two ion species, heavier ions facilitate formation of quasi-monoenergetic bunch of lighter ions. For circularly polarized light, fast electron production is suppressed by the absence of the oscillatory component of the ponderomotive force. Ions are accelerated on the front side by the separation field and very thin foil can be accelerated as one massive quasi-neutral block. As all ion species acquire the same velocity, this acceleration mechanism is preferred for heavier ions.

British Library Electronic Table of Contents (United Kingdom)

This work aimed to develop a fast-dissolving film made of low dextrose equivalent maltodextrins (MDX) containing nicotine hydrogen tartrate salt (NHT). Particular attention was given to the selection of the suitable taste-masking agent (TMA) and the characterisation of the ductility and flexibility under different mechanical stresses. MDX with two different dextrose equivalents (DEs), namely DE 6 and DE 12, were selected in order to evaluate the effect of polymer molecular weight on film tensile properties. The bitterness and astringency intensity of NHT and the suppression effect of several TMA were evaluated by a Taste-Sensing System. The films were characterised in term of NHT content, tensile properties, disintegration time and drug dissolution test. As expected, placebo films made of ...

International Nuclear Information System (INIS)

Anthracene-bis-resorcinol is an interesting molecule as it forms a hydrogen-bonded network when guest molecules with weak polarity are included. Focused ion beam (FIB) was irradiated on a part of its amorphous film with low dose, and the film was exposed to the vapor of guest molecules. From fluorescence and AFM analyses of this film, it was found that no inclusion compound was formed in FIB irradiated area, i.e. FIB irradiation suppresses the ability to form the inclusion compounds. By utilizing this phenomenon, we succeeded in a microfabrication of relief structures consisting of inclusion compounds which has different fluorescence from its surrounding. Morphology, fluorescence, and IR absorption analyses indicated that hydroxyl or resorcin groups are damaged by ion beams, and consequently a formation of hydrogen-bonded networks, which play a role of a lattice caging guest molecules, becomes impossible.

Energy Technology Data Exchange (ETDEWEB)

In order to apply chemical-looping combustion to a practical power plant, carbon deposition on the solid particle is one of the key problems to be overcome. Six kinds of solid particles were examined to clarify the kinetic behavior of carbon deposition. The effects of the solid composition, feed gas composition, and reaction temperature on carbon deposition were investigated by thermogravimetrical reactor on the basis of NiO/YSZ particle. From the viewpoints of both reactivity and resistance against carbon deposition, the particle of NiO mixed with YSZ (i.e., yttria-stabilized zirconia) was found to be a good candidate for chemical-looping combustion. It has been observed that carbon deposition could be completely avoided with very low concentration of water vapor. By means of a proposed model, the condition that carbon deposition would be avoided was identified. 12 refs., 8 figs., 2 tabs.

British Library Electronic Table of Contents (United Kingdom)

The obligate biotrophic fungus Golovinomyces orontii causes powdery mildew (PM) disease on its host Arabidopsis thaliana. Most research on the G. orontii?Arabidopsis pathosystem uses rosette leaves as experimental materials, so little is known about the behavior of G. orontii on other Arabidopsis organs. We thus conducted microscopic analyses of the PM infection process on leaves, stems, fruits and roots of Arabidopsis. Adaxial and abaxial surfaces of mature rosette leaves supported G. orontii infection, but growth was somewhat suppressed on cauline leaves. Prepenetration processes (germination and appressorium formation) were strongly inhibited on stems, fruits and roots. To test the effect of alterations in the Arabidopsis cuticle on the inhibition of prepenetration processes on stems, w...

Energy Technology Data Exchange (ETDEWEB)

A model is presented to account for the effects of ion-induced defects during implantation processing of Si. It will be shown that processing is quite generally affected by the presence of defect excesses rather than the total number of defects. a defect is considered excess if it represents a surplus locally of one defect type over its compliment. Processing spanning a wide range of implantation conditions will be presented to demonstrate that the majority of the total defects played little or no role in the process. This is a direct result of the ease with which the spatially correlated Frenkel pairs recombine either dynamically or during a post-implantation annealing. Based upon this model, a method will be demonstrated for manipulating or engineering the excess defects to modify their effects. In particular high-energy, self-ions are shown to inject vacancies into a boron implanted region resulting in suppression of transient enhanced diffusion of the dopant.

International Nuclear Information System (INIS)

The authors used studies of local cerebral metabolic rate for glucose (LCMRGlc) to examine development of cerebral organization in 5 days to 1 year old children. A group (n=8) of infants with diverse pediatric disorders allowed investigation of developmental changes in LCMRGlc, while also providing relevant clinical management information. Patients consisted of questionable and definite neonatal seizures, cerebral embolism from cardiac sources, and otherwise normal infants with facial nevi with consideration of Sturge-Weber. Gradual increase in cortical LCMRGlc coincides with suppression of intrinsic subcortical reflexes present in all newborns. Two retarded children (2 years old) showed LCMRGlc developmental patterns of a few days old, which corresponded to their functional and mental status. These studies illustrate great potential of PET to study normal and altered states of human brain development.

Energy Technology Data Exchange (ETDEWEB)

The difference between the two nonclassical lights, i.e., the squeezed state and number-phase minimum uncertainty state (NUS) is discussed. The four different generation principles for NUS are described. They are: unitary evolution using self-phase modulation; nonunitary state reduction by the first kind measurement; controlled state reduction by quantum correlation measurement-feedback, and high saturated laser oscillation with suppressed-pump-noise. The constant current-driven semiconductor laser based on the last principle generated the NUS with photon number noise reduced below the standard quantum limit by 40 percent in the entire frequency region from dc to 1.1 GHz. Several applications of NUS including quantum communication, quantum mechanical computers and interferometric gravitational detection are discussed briefly. This presentation is represented by viewgraphs only.

British Library Electronic Table of Contents (United Kingdom)

The flame retardancy of polybutylene terephthalate (PBT) was studied focusing on the effect of various oxides. Thermo-gravimetric analysis, pyrolysis/gas chromatography/mass spectrometry, and elemental analysis (EA) were used to analyze the flame retardancy, which were observed through the UL-test and a cone calorimeter. Many oxides influenced the flame retardancy and some of them could suppress the flammability of PBT. In particular, the blended-PBTs with ZnO and V2O5 accelerated the degradation and the edges of oxygen consumption were shorter than neat-PBT although the flammability became poorer. The quantitative analysis of the scission products and the results of EA showed that hydrolysis, successive dehydration, and other various reactions changed the scission route to generate less f...

International Nuclear Information System (INIS)

Purpose: To eliminate the water level deviation due to the recycling flowrate, as well as enable a stable control to a reference value even upon changes in the recycling flowrate caused by the variation in the opening degree of a minimum flow valve. Constitution: Reactor recycling system comprises a feedwater pump, a flowrate control valve, a reactor water level detector, and a minimum flow line and a minimum flow valve for preventing the overheating of the feedwater pump at a low flowrate. A flowrate compensator is further disposed, in which a recycling flowrate signal is subtracted from a pump flow rate signal and the result is fedback as a compensated pump flowrate signal. This enables the control system to operate at a rapid response for suppressing the effect of the recycling flowrate as external disturbance, whereby the water level in the reactor can be controlled stably to the reference level and the possibility deviating from an allowable range is decreased ...

Energy Technology Data Exchange (ETDEWEB)

Focussed ion beam (FIB) processing has been applied to the fabrication of novel InP-based cleaved coupled cavity (CCC) quantum cascade lasers (QCL). Gas assisted etching using XeF{sub 2} has been shown to significantly reduce the redeposition of sputtered material onto the mirror surfaces during final milling. For the unprocessed laser a broad spread of lasing peaks are observed between 9.72{mu}m to 9.78{mu}m at a current of 380mA (1kA/cm{sup -2}). After FIB processing, substantial side mode suppression is observed on applying a current of 20mA (100A/cm{sup -2}) to the short section and the main lasing peak is observed at 9.77{mu}m.

British Library Electronic Table of Contents (United Kingdom)

Measuring HPA axis activity is the standard approach to the study of stress and welfare in farm animals. Although the reference technique is the use of blood plasma to measure glucocorticoid hormones (cortisol or corticosterone), several alternative methods such as the measurement of corticosteroids in saliva, urine or faeces have been developed to overcome the stress induced by blood sampling itself. In chronic stress situations, as is frequently the case in studies about farm animal welfare, hormonal secretions are usually unchanged but dynamic testing allows the demonstration of functional changes at several levels of the system, including the sensitization of the adrenal cortex to ACTH and the resistance of the axis to feedback inhibition by corticosteroids (dexamethasone suppression t...

British Library Electronic Table of Contents (United Kingdom)

Erythroid differentiation regulator (Erdr1) was first discovered in mouse leukemia cell lines and functions as a stress-related survival factor. This study investigated whether Erdr1 regulates murine melanoma progression, as well as the mechanism involved in Erdr1-regulated metastasis. The expression of Erdr1 is negatively correlated with IL-18 expression, which has a pro-cancer effect in melanoma. To study the role of Erdr1 as an anti-cancer factor, cell migration, invasion, and proliferation were measured. Erdr1 overexpression markedly inhibited the level of cell migration, invasion, and proliferation in B16F10 cells in vitro. In addition, Erdr1 overexpression significantly suppressed melanoma lung colonization, metastasis, and tumor growth in vivo. To identify the factors involved in Er...

British Library Electronic Table of Contents (United Kingdom)

This study evaluated the clinical efficacy of treatment with oral risedronate (17.5?mg once daily) for 8?weeks in 11 Japanese patients with Paget?s disease of bone (PDB). Risedronate suppressed the excessive bone turnover associated with PDB and improved several biochemical markers, including serum alkaline phosphatase (ALP), serum bone-specific ALP (BALP), urinary deoxypyridinoline (DPD), and urinary cross-linked N-telopeptide of type 1 collagen (NTX). These markers began to decrease within about 2?weeks after the initiation of treatment in most patients, and the response persisted for up to 40?weeks after the cessation of treatment. Risedronate reduced pain by week 24 in most patients. According to quantitative bone scintigraphy, the lesion with the highest radioisotope (RI) uptake showe...

International Nuclear Information System (INIS)

The effects of intradot electron-electron interaction on the photon-assisted Andreev tunneling of a superconductor/carbon-nanotube/superconductor system are studied by using nonequilibrium Green's function technique. The inverse supercurrent reflecting the #pi#-junction transition emerges in the spin-split energy-levels regime polarized by the Coulomb interaction. For the positive tunneling case, the supercurrent reaches its maximum when the spin-degenerate energy-levels are nearest to the Fermi surface. Conversely, for the negative tunneling case, the supercurrent reaches its maximum when two split energy-levels are symmetric with respect of the Fermi surface. The sign and the amplitude of the Andreev tunneling depend distinctly on the energy-level spacing tuned by photon-assisted tunneling. In order to fully understand the transport characteristics, the current-carrying density of states are investigated, which clearly shows the enhancement, suppression or even ...

CERN Document Server

Searches for permanent electric-dipole moments (EDM) of atoms provide important constraints on competing extensions to the standard model of elementary particles. Recently proposed experiment with liquid $^{129}$Xe [M.V. Romalis and M.P. Ledbetter, Phys. Rev. Lett. \\textbf{87}, 067601 (2001)] may significantly improve present limits on the EDMs. To interpret experimental data in terms of CP-violating sources, one must relate measured atomic EDM to various model interactions via electronic-structure calculations. Here we study density dependence of atomic EDMs. The analysis is carried out in the framework of the cell model of the liquid coupled with relativistic atomic-structure calculations. We find that compared to an isolated atom, the EDM of an atom of liquid Xe is suppressed by about 40%.

International Nuclear Information System (INIS)

In this study, effects of alloying elements such as Mo, Cr and Ni on intergranular corrosion (IGC) resistance of Mo contained austenitic stainless steels in boiling 65% nitric acid solution (Huey Test) were studied. Obtained results are as follows; (1) Mo deteriorates IGC resistance of austenitic stainless steel in Huey test due to enhance precipitation of Laves ((Fe, Cr)_2Mo) phase at grain boundary. (2) Cr improves IGC resistance of Mo contained austenitic stainless steel in Huey test, which is considered to reduce dissolution rate of Laves phase into nitric acid solution by increasing Cr content in Laves phase as increasing Cr content of stainless steel. (3) Ni suppresses occurrence of IGC of Mo contained austenitic stainless steel in Huey test. (author).

Energy Technology Data Exchange (ETDEWEB)

To examine the hormonal regulation of the ATP-dependent Ca{sup 2+} pump in the kidneys, the ATP-dependent Ca{sup 2+} uptake by the basolateral membrane vesicles in the renal cortex was measured using radioactive calcium ({sup 45}Ca{sup 2+}) in rats with vitamin D deficiency or rats undergoing thyroparathyroidectomy. The V{sub max} of the Ca{sup 2+} pump activity was increased not only by administering calcitriol, but also by normalizing the serum calcium level in vitamin D-deficient rats. PTH suppressed the Ca{sup 2+} pump activity in normocalcemic vitamin D-deficient rats. Thyroparathyroidectomy did not affect the Ca{sup 2+} pump activity in the kidneys of normal rats. It was concluded that the ATP-dependent Ca{sup 2+} pump activity was depressed by secondary hyperparathyroidism in vitamin D-deficient rats. (author).

British Library Electronic Table of Contents (United Kingdom)

Abstract. Malaria vector control targeting the larval stages of mosquitoes was applied successfully against many species of Anopheles (Diptera: Culicidae) in malarious countries until the mid-20th Century. Since the introduction of DDT in the 1940s and the associated development of indoor residual spraying (IRS), which usually has a more powerful impact than larval control on vectorial capacity, the focus of malaria prevention programmes has shifted to the control of adult vectors. In the Afrotropical Region, where malaria is transmitted mainly by Anopheles funestus Giles and members of the Anopheles gambiae Giles complex, gaps in information on larval ecology and the ability of An. gambiae sensu lato to exploit a wide variety of larval habitats have discouraged efforts to develop and impl...

British Library Electronic Table of Contents (United Kingdom)

High purity W and W-0.9La2O3 (wt.%) nanopowders were produced by a wet chemical route. The precursor was prepared by the reaction of ammonium paratungstate (APT) with lanthanum salt in aqueous solutions. High resolution electron microscopy investigations revealed that the tungstate particles were coated with oxide precipitates. The precursor powder was reduced to tungsten metal with dispersed lanthanum oxide. Powders were consolidated by spark plasma sintering (SPS) at 1300 and 1400degreeC to suppress grain growth during sintering. The final grain size relates to the SPS conditions, i.e. temperature and heating rate, regardless of the starting powder particle size. Scanning electron microscopy revealed that oxide phases were mainly accumulated at grain boundaries while the tungsten matrix ...

International Nuclear Information System (INIS)

Cerium L_3 XANES (x-ray-absorption near-edge-structure) spectra were analyzed to separate Ce moment contributions and mixed valence (MV) in complex magnetic silicides CePd_2_-_xMn_xSi_2 (0#<=#x#<=#2). The Ce valence mixing does not vary linearly with x, but increases rapidly for x#>=#1.5. The associated moment collapse correlates with pronounced deviations of the unit-cell volume from Vegard law and the onset of structural instability. Reorientation of [001] Mn 3d antiferromagnetic order for x<2 appears to rapidly suppress the weak Ce valence mixing coexisting with antiferromagnetic order in CeMn_2Si_2.

Energy Technology Data Exchange (ETDEWEB)

We have investigated B diffusion in pre-amorphized silicon. In our experiments, the crystalline surface layer of silicon-on-insulator (SOI) substrates was completely amorphized by Ge ion implantation. Using SOI substrates in this fashion suppressed solid-phase-epitaxy regrowth, making it possible to investigate B diffusion in pre-amorphous silicon over a wider range of temperatures (500-650 deg. C) and times (5-1000 s) than has previously been reported. Diffusivities were determined with the aid of computational processes modeling. The results from this work demonstrate the B diffusion in a-Si is concentration dependent, exhibits a transient enhanced diffusion, and possesses an Arhennius behavior with activation energy of {approx}2.1 eV.

CERN Document Server

A new subcarrier combining technique is proposed for MC -CDMA receiver in mobile Rayleigh fading channel. It exploits the structure formed by repeating spreading sequences of users on different subcarriers to simultaneously suppress multiple access interference (MAI) and provide implicit channel tracking without any knowledge of the channel amplitudes or training sequences. This is achieved by adaptively weighting each subcarrier in each symbol period by employing a simple gradient descent algorithm to meet the constant modulus (CM) criterion with judicious selection of step-size. Improved BER and user capacity performance are shown with similar complexity in order of O(N) compared with conventional maximum ratio combining and equal gain combining techniques even under high channel Doppler rates.

CERN Document Server

A prescription is given for computing anomalous dimensions of single trace operators in SYM at strong coupling and large $N$ using a reduced model of matrix quantum mechanics. The method involves treating some parts of the operators as "BPS condensates" which, in certain limit, have a dual description as null geodesics on the $S^5$. In the gauge theory, the condensate is similar to a representative of the chiral ring and it is described by a background of commuting matrices. Excitations around these condensates correspond to excitations around this background and take the form of ``string bits" which are dual to the "giant magnons" of Hofman and Maldacena. In fact, the matrix model approach gives a {\\it quantum} description of these string configurations and explains why the infinite momentum limit suppresses the quantum effects. This method allows, not only to derive part of the classical sigma model Hamiltonian of the dual string (in the infinite momentum ...

British Library Electronic Table of Contents (United Kingdom)

Algal allelopathy is an ecological/physiological phenomenon that has focused attention on the interactions among algae and the production of algal toxins. We investigated the allelopathic interactions between the dinoflagellate genus Prorocentrum micans and diatom genus Skeletonema costatum and between P. micans and dinoflagellate genus Karenia mikimotoi using bi-algal cultures. Because the effects were species-specific and size-dependent, we evaluated the effect of different initial densities. At low densities of P. micans and high densities of S. costatum inoculated into the same medium, the growth of P. micans was weakly restrained, whereas the growth of S. costatum was significantly suppressed. S. costatum and K. mikimotoi were strongly inhibited by P. micans, in both the bi-algal cult...

British Library Electronic Table of Contents (United Kingdom)

Abstract The inhibitory effect of the extract from Magnolia officinalis (MOE) against L. monocytogenes, S. faecalis, E. coli, S. typhimurium, S. aureus and B. anthracis by paper-diffusion methods and the characterization of the mutton immersed in different concentrations of the MOE during storage were evaluated in this paper. The results showed that MOE could significantly inhibit the growth of S. aureus, S. faecalis, B. anthracis and E. coli, and their MIC was 0.02-mg/mL, 0.03-mg/mL, 0.05-mg/mL and 0.10-mg/mL, respectively. MOE showed weak inhibition for the S. typhimurium. The mutton treated with 2%, 4% and 6% MOE resulted in suppression in the increase of total volatile base nitrogen, thiobarbituric acid reactive substance, and the growth of Enterobacteriaceae, Pseudomonas. The cooled m...

International Nuclear Information System (INIS)

Dy doped #alpha#-SiAlON ceramics prepared by the hot-pressing method show a high optical transmittance value, >70%, in the infrared region of 1.5-4.5 #mu#m. First principles calculations have been carried out to reveal the underlying transparency mechanism. It is found that the valence shell of doped Dy atoms interacts strongly with the doping states of #alpha#-SiAlON, resulting in the increase in the optical gap from 0.4 to 1.1 eV, which suppresses the photoabsorption in the wavelength region longer than 1.0 #mu#m and leads to the good transparency property. The calculated optical transmission spectra are in good agreement with the corresponding experiments.

International Nuclear Information System (INIS)

Most of all research reactors are immerged in the deep water pool to be a ultimate heat sink. At the neighbor of the reactor, some radio-active matters, such as Na-24, Ar-41, Mg-27, Al-28 and etc, may be generated by the neutron irradiation. Those radio-active isotopes may rise up to the pool water surface through the natural convection flow, which can make the radioactivity in the reactor hall rise high enough to concern about the health of people working in the reactor hall. When the irradiation test facilities are loaded or unloaded during a normal operation, the highly radio-activated primary coolant may flow out through the irradiation test holes on the top of the reactor. This also may be a main hazard source to make the working environment of the reactor hall bad. Making a hot water layer 1.5 ? 2.0 m thick at the top of reactor pool would be a good measure to resolve that problem. The hot water layer is formed by a thermal stratification of pool water, which can effectively ...

International Nuclear Information System (INIS)

Radio frequency (RF) sheaths are suspected of limiting the performance of present-day ion cyclotron range of frequencies (ICRFs) antennas over long pulses and should be minimized in future fusion devices. Within the simplest models, RF-sheath effects are quantified by the integral VRF = ? E|| ? dl where the parallel RF field E|| is linked with the slow wave. On 'long open field lines' with large toroidal extension on both sides of the antenna it was shown that VRF is excited by parallel RF currents j|| flowing on the antenna structure. In this paper, the validity of this simple sheath theory is tested experimentally on the Tore Supra (TS) ITER-like antenna prototype (ILP), together with antenna simulation and post-processing codes developed to compute VRF. The predicted poloidal localization of high-|VRF| zones is confronted to that inferred from experimental data analysis. Surface temperature distribution on ILP front face, as well as ILP-induced modifications of RF coupling and hot ...

Science.gov (United States)

Decadal-scale climate variations over the Pacific Ocean and its surroundings are strongly related to the so-called Pacific decadal oscillation (PDO) which is coherent with wintertime climate over North America and Asian monsoon, and have important impacts on marine ecosystems and fisheries. In a near-term climate prediction covering the period up to 2030, we require knowledge of the future state of internal variations in the climate system such as the PDO as well as the global warming signal. We perform sets of ensemble hindcast and forecast experiments using a coupled atmosphere-ocean climate model to examine the predictability of internal variations on decadal timescales, in addition to the response to external forcing due to changes in concentrations of greenhouse gases and aerosols, volcanic activity, and solar cycle variations. Our results highlight that an initialization of the upper-ocean state using historical observations is effective for successful hindcasts of the PDO and ...

Energy Technology Data Exchange (ETDEWEB)

Elastic and elasto-plastic modelling of indentation in CFRP cross-ply laminates has been performed. Detailed knowledge of the field solutions in the volume below the indentor forms the basis for the reported micromechanical interpretation of the observed damage in test specimens. The analysis shows that matrix cracks originate at sites of maximum tensile stress perpendicular to fibers. The predicted stress fields due to indentation show that stress concentrations occur in the interface between alternating plies. It is found that microcracking in this zone is a precursor to the observed failure. This analysis is supported by in-situ scanning electron microscopy during loading by a cylindrical indentor onto the laminate supported on a rigid substrate. The microscopy reveals microdamage in the region of interfacial tensile stress concentrations. The onset of indentation failure in these layered composites suggests that plastic interleaves would delay failure. It is shown numerically that ...

International Nuclear Information System (INIS)

Field cage studies were carried out to evaluate the F_1 sterility technique for population suppression of the pink bollworm, Pectinophora gossypiella (Saunders), in cotton. For this purpose, six field cages (1.8 m x 1.8 m x 1.8 m) were placed over cotton seedlings in the field. Five pairs of laboratory reared, untreated adult moths were released in all six cages during the first week of August. In addition, on the same data 100 pairs of adults, following irradiation of the mature pupae at 100 Gy, were released in two cages and 250 such pairs of irradiated adults in two other cages in ratios of 20:1 and 50:1 (irradiated:normal), respectively. The results of per cent larval infestation in the rosette blooms in different field cages indicated that larval infestation in the flowers was significantly lower (4.93%) in cages where the moths were released at the 50:1 ratio than in cages where moths were released at the 20:1 ratio (6.71%). Larval infestation in the flowers ...