Several series of pyrimidine nucleosides were evaluated as part of a larger program to develop non-invasive brain imaging agents. The interaction of these antitumor/antiviral nucleosides with an NBMPR-sensitive murine erythroctye nucleosidetransporter was evaluated by determining their inhibitory effect (K_i) on zero-trans influx of thymidine. Within each series of compounds, which had F, Cl, Br or I as halogen substituents, an increase in size of the halogen atom or a decrease in electronegativity decreased affinity for the transporter. Partition coefficients (P) of these pyrimidine nucleosides were measured to determine their potential to diffuse across the blood-brain-barrier (BBB). Most of the pyrimidine nucleosides had lower P values (log P < 0.9), and were considered to be poor candidates for simple diffusion across the BBB, ...
During germination and early growth of castor bean (Ricinus communis), all cellular constituents of the endosperm are eventually transferred to the growing embryo. The present results...Full Text Available
Conformationally constrained analogue synthesis was undertaken to aid in pharmacophore mapping and 3D-QSAR analysis of nitrobenzylmercaptopurine riboside (NBMPR) congeners as equilibriative nucleosidetransporter 1 (ENT1) inhibitors. In our previous study [J. Med. Chem. 2003, 46, 831-837], novel regioisomeric nitro-1,2,3,4-tetrahydroisoquinoline conformationally constrained analogues of NBMPR were synthesized and evaluated as ENT1 ligands. 7-NO2-1,2,3,4-Tetrahydroisoquino-2-yl purine riboside was identified as the analogue with the nitro group in the best orientation at the NBMPR binding site of ENT1. In the present study, further conformational constraining was introduced by synthesizing 5prime-O,8-cyclo derivatives. The flow cytometrically determined binding affinities indicated that the...
Nucleoside 3'-phosphoramidite and chlorophosphite reagents have been found to react with the lactam function of guanine. This reaction caused unsatisfactory results when oligodeoxyribonucleotides containing...Full Text Available
Alkyl halides react rapidly with purines and pyrimidines in the presence of fluoride ion. Alkylation of thymidine leads to novel dimeric nucleoside derivatives bridged through N3. Alkylation of thymidine...Full Text Available
We present recent results obtained in the Toulouse's group that deal with proton to base and nucleoside interactions. We stress the weakness of the sugar part in the nucleoside, i.e. the uridine molecule under scrutiny. Since some parts of the fragmentation spectrum correspond to the fragmentation of a 'pure' uracil molecule, i.e. the RNA base, an 'additivity rule' seems to prevail for the nucleoside, something that still has to be confirmed. Moreover, some results that deal with the secondary electronic emission from uracil are also displayed.
The non-natural pyrido[2,3-d]pyrimidine nucleoside F, which pairs preferentially with guanine (G) and adenine (A) within double-helical DNA, recognizes with high selectivity AT base pairs within triple-helical...Full Text Available
Daily oral treatment with the cyclopentyl 2′-deoxyguanosine nucleoside BMS-200475 at doses ranging from 0.02 to 0.5 mg/kg of body weight for 1 to 3 months effectively reduced the level of woodchuck...Full Text Available
Post-transcriptional nucleoside modifications fine-tune the biophysical and biochemical properties of transfer RNA (tRNA) so that it is optimized for participation in cellular processes. Here we report...Full Text Available
BackgroundStem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target cancer stem cells...Full Text Available
Telbivudine is a novel nucleoside drug recently approved for the treatment of patients with chronic hepatitis B. Its nonclinical safety was evaluated in a comprehensive program of studies, including...Full Text Available
Biological motors generally fall into two categories: (1) those that convert chemical into mechanical energy via hydrolysis of a nucleoside triphosphate, usually adenosine triphosphate, regarded as life's chemical currency of energy and (2) membrane bound motors driven directly by an ion gradient and/or membrane potential. Here we argue that electrostatic interactions play a vital role for both types of motors and, therefore, the tools of physics can greatly contribute to understanding biological motors.
A nucleoside triphosphate binding site on calf thymus RNA polymerase II was identified by using photoaffinity analogues of adenosine 5'-triphosphate and guanosine 5'-triphosphate. Both radiolabeled 8-azidoadenosine 5'-triphosphate (8-N3ATP) and radiolabeled 8-azidoguanosine 5'-triphosphate (8-N3GTP) bound to a single polypeptide of this enzyme. This polypeptide has a molecular mass of 37 kilodaltons and an isoelectric point of 5.4. Ultraviolet (UV) irradiation was necessary for photolabeling to occur. In addition, no labeling occurred when the probe was prephotolyzed or when the enzyme was inactivated. Furthermore, photolabeling of the enzyme could be decreased by preincubation with natural substrates. To provide evidence that the radiolabeled polypeptide forms a part of the domain of the nucleoside triphosphate binding site, experiments were performed using unlabeled 8-N3ATP. Although this unlabeled analogue ...
Airway ciliated cells express an ATP-gated P2X receptor channel of unknown subunit composition (P2Xcilia) which is modulated by Na+ and by long exposures to ATP. P2Xcilia...Full Text Available
In vivo effects of toxaphene on calcium pump activity in rat brain synaptosomes was studied. Male Sprague-Dawley rats were dosed with toxaphene at 0,25,50, and 100 mg/kg/day for 3 days and sacrificed 24 h after last dose. Ca"2"+-ATPase activity and "4"5Ca uptake were determined in brain P_2 fraction. Toxaphene inhibited both Ca"2"+-ATPase activity and "4"5Ca"2"+ uptake and the inhibition was dose dependent. Both substrate and Ca"2"+ activation kinetics of Ca"2"+-ATPase indicated non-competitive type of inhibition as evidenced by decreased catalytic velocity but not enzyme-substrate affinity. The inhibited Ca"2"+-ATPase activity and Ca"2"+ uptake were restored to normal level by exogenously added calmodulin which increased both velocity and affinity. The inhibition of Ca"2"+-ATPase activity and Ca"2"+ uptake and restoration by calmodulin suggests that toxaphene may impair active calcium transport mechanisms by decreasing ...
Three novel inosine-based dinuclear platinum complexes have been synthesized via a solid-phase strategy. In these compounds, the metal is linked both to the N-7 of the purine nucleus and to the terminal amine group of a hexylamine side chain installed on N-1. Cis- or trans- diamine as well as ethylenediamine ligands are coordinated to platinum along with a chloride. The synthesised complexes were tested against four different human tumor cell lines. One of these complexes proved to be more cytotoxic than cisplatin against the MCF7 cancer cell line in a short-term exposure assay.
Ionotropic P2X and metabotropic P2Y purinergic receptors are expressed in the central nervous system and participate in the synaptic process particularly associated with acetylcholine, GABA, and glutamate...Full Text Available
BackgroundXMRV (xenotropic murine leukemia virus-related virus) is the first known example of an exogenous gammaretrovirus that can infect humans. A limited number of reports suggest that XMRV is intrinsically resistant to many of the antiretroviral drugs used to treat HIV-1 infection, but is sensitive to a small subset of these inhibitors. In the present study, we used a novel marker transfer assay to directly compare the antiviral drug sensitivities of XMRV and HIV-1 under identical conditions in the same host cell type.ResultsWe extend the findings of previous studies by showing that, in addition to AZT and tenofovir, XMRV and HIV-1 are equally sensitive to AZddA (3'-azido-2',3'-dideoxyadenosine), AZddG (3'-azido-2',3'-dideoxyguanosine) and adefovir. These results indicate that specific 3'-azido or acyclic nucleoside analog inhibitors of HIV-1 reverse transcriptase (RT) also block XMRV infection with comparable efficacy in vitro. Our data confirm that XMRV is ...
The structure of the P-2, S-1 accelerator mode with one step, S-1, on double period, P-2 for systems, described by the Harper mapping as well as by standard mapping, is analyzed. Detailed analysis of stability criteria is given and comparison with the results of numerical analysis is performed. Three-period compression of the P-2, S-1 island is revealed in the standard mapping. Refs. 7, figs. 7.
BackgroundTo evaluate whether P2X receptors are involved in responses to noxious pulp stimulation, the P2X3 and P2X2/3 receptor agonist α,β-methyleneATP...Full Text Available
We present the effect of P2O5 addition on barium calcium aluminum borosilicate BCABS glasses of composition (mol %) 35BaO-15CaO-5Al2O3-(37-x)SiO2-8B2O3-xP2O5 (0?x?5). The incorporation of P2O5 increased network polymerization and crystallization tendency. However, addition of P2O5 leads to the formation of Cr2O3 at the interface, saturating it in the ions of the metal. This improves glass-to-metal bonding. (author)
Carbohydrate and nucleotide structural determination using modern spectroscopic techniques is dependent on our ability to label oligonucleotides and oligosaccharides with stable isotopes. Uniform Carbon 13 and Nitrogen 15 labeling of oligonucleotides is important to present-day efforts, which are focused on determining the structure of relatively small oligosaccharides and oligonucleotides, which form the elements of larger structures. Because of the relatively recent interest in three-dimensional structure, the development of techniques used to label them has lagged behind parallel techniques used to label peptides and proteins. Therefore, this group`s discussion focused primarily on problems faced today in obtaining oligonucleotides labeled uniformly with carbon 13 and nitrogen 15.
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized. Here, we report two crystallographic structures of human UPP2 (hUPP2) in distinctly active and inactive conformations. These structures reveal that a conditional intramolecular disulfide bridge can form within the protein that dislocates a critical phosphate-coordinating arginine residue (R100) away from the active site, disabling the enzyme. In vitro activity measurem...
The existence of n-particle n-hole deformed yrare bands in the N=28 isotones is explored using full pf-shell diagonalizations and the Lanczos Strength Function method. We find different 2p-2h and 4p-4h collective bands that, when allowed to mix, more often disappear. Only the 2p-2h yrare band in Cr-52 and the 4p-4h yrare band in Ni-56 survive, and only in this latter case, due to the reduced density of 2p-2h states, can the band be seen as a gamma-cascade.
ObjectiveWe wanted to evaluate the status of self-expandable nitinol stents implanted in the P2 and P3 segments of the popliteal artery in Korean patients.Materials...Full Text Available
Although previous studies have provided evidence for the expression of P2X receptors in renal proximal tubule, only one cell line study has provided functional evidence. The current study investigated...Full Text Available
P2X1 receptors for ATP contribute to signalling in a variety of cell types and following stimulation undergo rapid desensitisation (within 1 s), and require ∼5 min to recover. In HEK293 cells...Full Text Available
1. Using a grease-gap recording technique we have investigated the effects of some antagonists of P2-purinoceptors on the depolarization of the rat isolated superior cervical ganglion evoked by 100...Full Text Available
T-cell activation requires the influx of extracellular calcium, although mechanistic details regarding such activation are not fully defined. Here, we show that P2X7 receptors play a key...Full Text Available
Glasses in the system (95-x) [0.25 Na2O-0.75 B2O3]-x P2O5-5 Fe2O3 (0?x?15 mol%), have been prepared by the melt quenching technique. Elastic properties and FT-IR spectroscopic studies have been employed to study the role of P2O5 on the structure of the glass system. Elastic properties Poisson's ratio, micro-hardness and Debye temperature have been investigated using sound wave velocity measurements at 4 MHz (both longitudinal and shear) at room temperature. The results showed that the density and the molar volume increase as both sound velocities and the determined glass transition temperatures decrease with increasing the contents of P2O5. Infrared spectra of the glasses reveal that the borate network consists of diborate units and is affected by the increase in the concentration of P2O5 content as a second network ...
Enhancing transport sustainability is the password of national, European, and international policies. The development of innovative solutions is ranging from bio fuels to transport analysis models, materials, traction technologies, mobility management, freight villages.
We wanted to evaluate the status of self-expandable nitinol stents implanted in the P2 and P3 segments of the popliteal artery in Korean patients. We retrospectively analyzed 189 consecutive patients who underwent endovascular treatment for steno occlusive lesions in the femoropopliteal artery from July 2003 to March 2009, and 18 patients who underwent stent placement in popliteal arterial P2 and P3 segments were finally enrolled. Lesion patency was evaluated by ultrasound or CT angiography, and stent fracture was assessed by plain X-rays at 1, 3, 6 and 12 months and annually thereafter. At the 1-month follow-up, stent fracture (Type 2) was seen in one limb (up to P3, 1 of 18, 6%) and it was identified in seven limbs at the 3-month follow-up (Type 2, Type 3, Type 4) (n = 1: up to P2: n = 6: P3). At the 6-month follow-up, one more fracture (Type 1) (up to P3) was ...
This report presents a general investigation of the transport requirements associated with the construction and operation of conceptual fusion reactors. Projections of amounts of construction and operating materials requiring transportation are presented for several proposed designs. The material to be shipped is described along with the shipping containers that might be used, the transport modes and the expected impact of transporting these materials. Transportation of both radioactive and nonradioactive materials will be required. Most of these materials are routinely shipped by the transportation industry. Transportation requirements of a representative fusion reactor are also compared with Liquid Metal Fast Breeder Reactor (LMFBR) requirements.
This paper presents a supernetwork equilibrium model integrating supply chain networks with a transport network, namely, a supply chain-transport supernetwork equilibrium model. The model takes into account the behaviour of freight carriers and transport network users to endogenously determine the transport costs generated in the supply chain networks. The interaction between transport network and supply chain networks can also be examined. Results of the numerical tests reveal that the improvement of transport network could enhance the efficiency of supply chain networks. The paper makes contributions to modelling of supply chain networks as well as to that of transport networks.
Good performance in extended lactations of dairy cattle may have a beneficial effect on food costs, health, and fertility. Because data for extended lactation performance is scarce, lactation persistency has been suggested as a suitable selection criterion. Persistency phenotypes were calculated in several ways: P1 was yield relative to an approximate peak, P2 was the slope after peak production, and P3 was a measure derived to be phenotypically uncorrelated to yield and calculated as a function of linear regressions on test-day deviations of days in milk. Phenotypes P1, P2, and P3 were calculated for sires as solutions estimated from a random regression model fitted to milk yield. Because total milk yield, calculated as the sum of daily sire solutions, was correlated to P1 and P2 (r=0.30 ...
Callus cultures of Calophyllum inophyllum were established using seed, nodal/ internodal and leaf explants on WPM basal medium supplemented with indole-3-butyric acid (IBA), a-naphthalene acetic acid (NAA), picloram (4-amino-3,5,6-trichloropicolinic acid), and 6-benzylaminopurine (BAP) in different combinations and concentrations with the view to study the influence of hormones on callus induction and the pattern of expression of dipyranocoumarins including anti-HIV, non-nucleoside reverse transcriptase inhibitors inophyllum B and P in callus cultures. 96.01% seed explants, 87.50% nodal/internodal explants and 86.66% leaf explants were converted into calluses when inoculated on WPM supplemented with IBA 4.0mgl-1 along with BAP 1.0mgl-1, IBA 4.0mgl-1, and picloram 6.0mgl-1 along with BAP 2....
A comprehensive and highly selective method for detecting in bacterial supernatants a modified sulfur nucleoside, S-adenosyl-L-methionine (SAM), and its metabolites, i.e., S-adenosylhomocysteine (SAH), adenosine (Ado), 5prime-deoxy-5prime-methylthioadenosine (MTA), adenine (Ade), S-adenosyl-methioninamine (dcSAM), homocysteine (Hcy) and methionine (Met), was developed. The method is based on reversed-phase liquid chromatography with positive electrospray ionization (ESI+) coupled to a hybrid linear quadrupole ion trap (LTQ) and 7-T Fourier transform ion cyclotron resonance mass spectrometry (FTICRMS). A gradient elution was employed with a binary solvent of 0.05 M ammonium formate at pH 4 and acetonitrile. The assay involves a simultaneous cleanup of cell-free bacterial broths by solid-pha...
The overall objective of this project has been to develop immunochemical methods to quantitate unique DNA base damages in order to facilitate studies on radiation-induced damage production and repair. Specifically, we have been using antibodies raised to damaged bases to quantitate unique lesions in model systems in order to evaluate their potential biological consequences. Our approach has been to synthesize modified nucleotides or nucleosides, conjugate them to protein carriers, and use the conjugates as immunogens in rabbits or to prepare monoclonal antibodies. We have been studying damages that are stable radiolysis products found in X-irradiated DNA and thus of potential biological consequence. Our aim is to build an in vitro and in vivo data base on the interactions between model DNA lesions and such cellular enzymes as DNA polymerases and repair endonucleases. Initial studies have focused on pyrimidine ring saturation products (thymine glycol.and ...
The overall objective of this project has been to develop immunochemical methods to quantitate unique DNA base damages in order to facilitate studies on radiation-induced damage production and repair. Specifically, we have been using antibodies raised to damaged bases to quantitate unique lesions in model systems in order to evaluate their potential biological consequences. Our approach has been to synthesize modified nucleotides or nucleosides, conjugate them to protein carriers, and use the conjugates as immunogens in rabbits or to prepare monoclonal antibodies. We have been studying damages that are stable radiolysis products found in X-irradiated DNA and thus of potential biological consequence. Our aim is to build an in vitro and in vivo data base on the interactions between model DNA lesions and such cellular enzymes as DNA polymerases and repair endonucleases. Initial studies have focused on pyrimidine ring saturation products (thymine glycol.and ...
G-protein-coupled receptor signalling has been suggested to be voltage dependent in a number of cell types; however, the limits of sensitivity of this potentially important phenomenon are unknown. Using...Full Text Available
Acute inflammation is important for tissue repair; however, chronic inflammation contributes to neurodegeneration in Alzheimer’s disease (AD) and occurs when glial cells undergo prolonged...Full Text Available
Background and purpose:The chicken anterior mesenteric artery contains an outer longitudinal smooth muscle layer, whose neural regulation remains to be elucidated. ATP evokes a depolarization...Full Text Available
Congenital woolly hair is a disorder with structural defects of the hair shafts. Curled hairs are noticed at birth or soon after birth and often improve with age. Some cases of woolly hairs are associated...Full Text Available
The Danish Ministry of Transportation has prepared a national plan of transportation, for the years until 2005. Official policy concerning land, maritime and air transport, personal and cargo transportation, investments and expenditures is outlined. Environmental impacts of energy consumption and air pollution abatement measures are considered. (EG)
The change of the transport coefficient due to the fusion energy source is studied. The scale invariance property of the reduced set of equations is investigated in the presence of the self-heating term due to the fusion reaction. The pressure gradient as well as the fusion power are the free energy sources that dictate the turbulent transport. It is shown that the burning transport coefficient can have a form with much wider variety, and that the transport property could be different owing to the self-heating by the fusion reactions. (author)
Alterations in mass transport patterns of low-density lipoproteins (LDL) and oxygen are known to cause atherosclerosis in larger arteries. We hypothesise that the species transport processes in coronary...Full Text Available
ATP-binding cassette transporters (ABC transporters) utilize the energy of ATP hydrolysis to translocate an unusually diverse set of substrates across cellular membranes. ABCA4, also known as...Full Text Available
The transport of serine into tobacco (Nicotiana tabacum L. var. Xanthi) cells grown in liquid medium was studied. Serine transport was maximal below pH 4.0. A time-dependent stimulation...Full Text Available
Transport of negative ion beams through plasma is reviewed. The effect of space charge on beam stability and beam emittance is discussed. The approaches to the beam transport problem developed at Los Alamos, Berkeley, Oak Ridge and Culham Laboratory are intercompared. (AIP)
Nutrient transport affinities of nutrient-starved microbial populations were measured as initial slopes of plots of limiting-nutrient transport rates versus extracellular limiting-nutrient concentrations....Full Text Available
Citrate transport via CitS of Klebsiella pneumoniae has been shown to depend on the presence of Na+. This transport system has been expressed in Escherichia coli, and uptake of citrate in E. coli membrane...Full Text Available
To gain insight into ATP-binding cassette transporter A1 (ABCA1) function and its potential role in AD pathology, we analyzed the expression of the cholesterol transporter ABCA1...Full Text Available
Amino acid transport was studied in membrane vesicles of the thermophilic anaerobic bacterium Clostridium fervidus. Neutral, acidic, and basic as well as aromatic amino acids were transported at 40...Full Text Available
Many auxin responses are dependent on redistribution and/or polar transport of indoleacetic acid. Polar transport of auxin can be inhibited through the application of phytotropins such as 1-naphthylphthalamic...Full Text Available
This paper shows that a well designed transport system has an embedded exchange value by serving as a market for potential exchange between consumers. Under suitable conditions, one can improve the welfare of consumers in the system simply by allowing some exchange of goods between consumers during transportation without incurring additional transportation costs. We propose an explicit valuation formula to measure this exchange value for a given compatible transport system. This value is always nonnegative and bounded from above. Criteria based on transport structures, preferences and prices are provided to determine the existence of a positive exchange value. Finally, we study a new optimal transport problem with an objective taking into account of both transportation cost and exchange value.
BackgroundWith the exception of vertebrates, most organisms have plasma membrane associated ammonium transporters which primarily serve to import a source of nitrogen for nutritional...Full Text Available
The relative transport capabilities of the cells of the root periphery and cortex were investigated using a variety of experimental techniques. Brief (30 seconds to 1 minute) exposures with the penetrating...Full Text Available
... Marine transport and oil disposal by boats and Matadi pose threats in the region. When the water ... Marine transport and oil disposal by boats and Matadi pose threats in the region. When the water ... ...
We utilize existing inclusive data on K{sup +}-meson momentum spectra of the reaction pp{yields}K{sup +}X at T{sub p}=2.3-2.85 GeV to deduce total cross-sections for pp{yields}K{sup +}{sigma}{sup +}n. The method used to extract those cross-sections is explained and discussed in detail. Our result for T{sub p}=2.85 GeV is consistent with the data point from a direct measurement at the same beam energy. The cross-section obtained for T{sub p}=2.3 GeV is with 13.7{+-}2.3 {mu}b considerably smaller than the value found in a recent experiment by the COSY-11 Collaboration at a somewhat lower beam energy, indicating that the pp{yields}K{sup +}{sigma}{sup +}n reaction cross-section could exhibit a rather unusual energy dependence. (orig.)
The excitation cross sections by electron impact from the Cd II ground state to the laser upper state 5s_2 _2D/sub 5/2/ (Beutler state) and the laser lower state 5p _2P/sub 3/2/ (resonance state) have been measured by using a crossed-beam method of electrons and Cd"+ ions and a photon-counting method. The electron-energy region investigated was from the threshold energy (5.8 eV) for the excitation of the 5p _2P/sub 3/2/ state to 20 eV. It has been shown that the excitation cross section for the ionic Beutler state 5s_2 _2D/sub 5/2/ is of the order of 10"-_1_5 cm_2 and has a sharp peak near the threshold energy for the excitation. The excitation cross section for the resonance state 5p _2P/sub 3/2/ has also been of the order of 10"-_1_5 cm_2 and has a relatively broad maximum.
The corrosion inhibition of C38 steel in molar HCl by N,N-bis[2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl]buthylamine (P1) and 5-{N,N-bis[2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl] amino} pentanol (P2) has been investigated at 308?K using electrochemical and weight loss measurements. Measurements show that these compounds act as good inhibitors without changing the mechanism of the corrosion process. Moreover, the inhibiting efficiency increases with the increase in concentration of the studied inhibitors. Compound P2 showed better protection properties even at relatively higher temperatures when compared to P1. The associated activation corrosion and free adsorption energies have been determined. P1 and P2 are adsorbed on the C38 steel surface according to a Langmuir isotherm adsorption model.
Electron elastic and collisional excitation cross sections from the ground state of potassium are calculated using the noniterative integral-equation method of Henry, Rountree, and Smith [Comput. Phys. Commun. 23, 233 (1981)] in the electron energy range 4#<=#E#<=#200 eV. Configuration-interaction target wave functions that take account of correlation and polarization effects are used to represent the ground state and the six lowest excited states 4p "2P degree, 5s "2S, 3d "2D, 5p "2P degree, 4d "2D, and 6s "2S. Elastic and discrete excitation cross sections are obtained in a seven-state close-coupling (7CC) approximation. The 7CC elastic and excitation cross sections are compared and contrasted. Near threshold the elastic cross section dominates the resonance, 4s "2S#->#4p "2P degree, and the sum of the other remaining excitation cross sections. ...
Studies on the large scale peer-to-peer (P2P) network like Gnutella have shown the presence of large number of free riders. Moreover, the open and decentralized nature of P2P network is exploited by malicious users who distribute unauthentic or harmful contents. Despite the existence of a number of trust management schemes in the literature for combating against free riding and distribution of malicious files, these mechanisms are not scalable due to their high computational, communication and storage overhead. These schemes also do not consider effect of trust management on quality-of-service (QoS) of the search. This paper presents a trust management scheme for P2P networks that minimizes distribution of spurious files by a novel technique called topology adaptation. It also reduces search time since most of the queries are resolved within the community of ...
The formation of a porous coating is the decisive feature for the bio-compatibility of silica-free calcium phosphate glass ceramics on alloy surfaces like the #beta#-Ti structured Ti-29Nb-13Ta-4.6Zr used in this work. The ceramic composition is highly important: 50CaO-40P_2O_5-7Na_2O-3TiO_2 glass powder produces a pore-free coating unable to bind hydroxyapatite, whereas 60CaO-30P_2O_5-7Na_2O-3TiO_2 glass incorporates pores from which a crystalline hydroxyapatite phase can grow over the surface from simulated body fluid (see Figure). (Abstract Copyright [2003], Wiley Periodicals, Inc.)
This work presents accurate ab initio determination of the hyperfine splitting for the ground state and few low-lying excited states of 113Cd+; important candidates for the frequency standard in the microwave region, using coupled-cluster theory (CC) in the relativistic framework. The calculated hyperfine splitting are well in agreement with recent experimental results. We have also carried out the lifetimes of the 5p2P1=2 and 5p2P3=2 states, which are in well agreement with recent experimental result (Moehring et al., PRA 73 023413, 2006). The roles of different electron correlation effects in the determination of these quantities are discussed and their contributions are presented in the CC terms.
A method to deduce the 2 x 2 transport matrix for coupled heat and particle transport in Tokamaks is proposed. The method applies to perturbative experiments, and is based on a Fourier transform of the measured signals of temperature and density. By analyzing different linear combinations of temperature and density, the eigenvectors and eigenvalues of the transport matrix are determined. The method is tested for a number of illustrative cases using simulated data, and the sensitivity to noise on the signals is evaluated. (author).
Development of the engineering technology basis of pyrometallurgical reprocessing is a key issue for industrialization. For development of the transport technologies of molten salt and liquid cadmium at around 773 K, a salt transport test rig and a metal transport test rig were newly installed in an Ar glove box. Function of the salt transport test rig was confirmed with LiCl-KCl molten salt, and the transport behaviour of molten salt was found to follow that of water. The molten salt/liquid metal contactor for Ln/An separation was newly designed and installed. The test with a single-stage contactor was successful with simulated elements, and a three-stage contactor is now under development. A large-scale electro-refiner with a function to transport molten salt and liquid cadmium were newly designed, and to be installed for demonstration test with simulated ...
In drug development, Caco-2 cells are often employed to study the influence of membrane transporters on drug permeability. The aim of the current study was to characterize permeability and kinetic parameters of selected organic anionic compounds in Caco-2 cells, and to investigate whether the Caco-2 cell line may be used as an overall model to predict interactions on multiple membrane transporters in the intestine. Taurocholic acid (TCA) and estrone-3-sulfate (E(1) S) were used as model substrates. Possible inhibitors studied were TCA, E(1) S, taurolithocholic acid, fluvastatin, and glipizide. The effects of these compounds on initial uptake, apparent permeability, and intracellular end-point accumulations of the probe substrates were studied. Both interactions on apical and basolateral influx transporters were observed. These interactions were proposed to be mediated mainly by the apical sodium-dependent bile acid ...
The survey of radiation protection programmes for transport has been jointly performed by three scientific organisations I.P.S.N. (France), G.R.S. ( Germany), and N.R.P.B. (United kingdom) on behalf of the European Commission and the pertaining documentation summarises the findings and conclusions of the work that was undertaken with the principal objectives to provide guidance on the establishment, implementation and application of radiation protection programmes for the transport of radioactive materials by operators and the assessment and evaluation of such programmes by the competent authority and to review currently existing radiation protection programmes for the transport of radioactive materials. (N.C.)
Solenoid transport of high current, heavy ion beams is considered for several stages of a heavy ion fusion driver. In general this option is more efficient than magnetic quadrupole transport at sufficiently low kinetic energy and/or large e/m, and for this reason it has been employed in electron induction linacs. Ideally an ion beam would be transported in a state of Brillouin flow, i.e. cold in the transverse plane and spinning at one half the cyclotron frequency. The design of appropriate solenoids and the equilibrium and stability of transported ion beams are discussed. An outline of application to a fusion driver is also presented.
This short survey focuses on the main radiation-induced base lesions that have been identified within cellular DNA. For this purpose, sensitive assays that are aimed at measuring a few modifications per 10{sup 7} normal bases were set-up. In that respect high performance liquid chromatography - tandem mass spectrometry (CLHP-MS/MS) was found to be able to single out the formation of 9 oxidized nucleosides and two modified nucleo-bases out of the 70 oxidative base lesions that have been identified in model systems. As a striking result, it was found that in the DNA of {gamma}-irradiated human monocytes, the formamide-pyrimidine derivative of guanine is produced in a higher yield than the ubiquitous 8-oxo-7,8-dihydro-guanine damage, both arising from the same radical precursor. However, relatively high doses of ionizing radiation (> 20 Gy) have to be applied in order to detect an increase in the level of the damage. This is due to the low efficiency for both ...
A single amino acid substitution (Asp #-># Asn) at position 138 of E. coli EF-Tu was induced in the tufA gene by an M13 phage oligonucleotide site-directed mutagenesis protocol. The mutated tufA gene was then subcloned in a plasmid vector and expressed in maxicells. The properties of ["3"5S]methionine labelled mutant and wild type EF-Tu's were compared by in vitro assays. Mutant and wild-type EF-Tu's bound EF-Ts with approximately equal affinities. The 138-Asn mutation greatly reduced the protein's affinity for GDP; however, this mutation dramatically increased the proteins affinity for XDP. The mutant protein forms a stable complex with phe-tRNA and XTP, which binds to ribosomes; whereas, it does not form a complex with phe-tRNA and GTP. These results suggest that in EF-Tu x NDP complexes amino acid residue 138 must interact with the substituent on C-2 of the purine ring. Thus in wild-type EF-Tu Asp-138 would H-bond to 2-NH_2 of GDP, and in the mutant EF-Tu ASN-138 would form an ...
Background2-Methylthioadenosine 5'-triphosphate (2-MeSATP), formerly regarded as a specific P2Y (metabotropic) purinergic receptor agonist, stimulates Ca2+ influx and...Full Text Available
Apparent molar heat capacities for KI[sub 3](aq) were determined from flow-microcalorimetric measurements of KI(aq) solutions containing dissolved iodine. From these, the conventional partial molar heat capacity C[sub p,2][sup [infinity
Extracellular ATP has been proposed as a paracrine signal in rodent islets, but it is unclear what role ATP plays in human islets. We now show the presence of an ATP signaling pathway that enhances...Full Text Available
A stochastic-convective reactive (SCR) transport method is developed for one-dimensional steady transport in physically heterogeneous media with nonlinear degradation. The method is free of perturbation amplitude limitations and circumvents the difficulty of scale dependence of phenomenological parameters by avoiding volume-averaged specifications of diffusive/dispersive fluxes. The transport system is conceptualized as an ensemble of independent convective-reactive streamlines, each characterized by a randomized convective velocity (or travel time). Dispersive effects are treated as a component of the randomness in the streamline velocity ensemble, so no explicit expression for hydrodynamic dispersive flux is written in the streamline transport equation. The expected value of the transport over the stream tube ensemble is obtained as an average of solutions to the reactive ...
The aim of this work is to understand the reasons for the selectivity shown in the complexation by unsaturated heteropolyanions (HPA) of actinides (An) which are oxidized to the number +IV. Different studies have been carried out, both in solution and in solid state, on P_2W_1_7O_6_1"1"0"- and its complexes with Zn"2"+, UO_2"2"+, Ce"4"+, Th"4"+ and U"4"+ to characterize the nature of the complexation site offered to the cation. Among the actinides(IV), the U"4"+ ion has been selected due to its singular spectroscopic and magnetic properties. An initial series of studies, in solution, using NMR"3"1P has thus enabled us to characterize these complexes and to compare them to those formed with the complexing agent PW_1_1O_3_9"8"-. This body of data allows to identify an identical complexation site for both ligands. An analysis of the NMR"3"1P spectrum of U(P_2W_1_7O_6_1)_2"1"6"- has shown a plane of ...
The interfacial area transport equation dynamically models two-phase flow regime transitions and predicts continuous changes of the interfacial area concentration along the flow field. It replaces the flow regime-dependent correlations for the interfacial area concentration in thermal-hydraulic system analysis. In the present study, detailed formulation of the interfacial area transport equation is presented along with its evaluation results based on the detailed benchmark experiments. In view of model evaluation, the equation is simplified into one-dimensional steady state one-group interfacial area transport equation. The prediction made by model agrees well with the experimental data obtained in round pipes of various diameters. The framework for the two-group transport equation and the necessary constitutive relations are also presented in view of bubble transport of various ...
Kawasaki Steel started the construction of an automatic steel strip coil transportation system in the 1980's. Presently, most of the in-plant transportation of hot-rolled or cold-rolled coils are automated. For establishing the automatic transportation, there were developed various technologies, such as, the optimum handling technology using artificial intelligence, the technology of preventing additional piling of coils on existing coils by using an ultrasonic wave and a laser beam. Through the improvements of these technologies, a full-automated transportation system has been achieved and the system has contributed substantially toward product quality assurance and cost reduction. This paper gives the changes in the automation technology of coil transportation in the automation of No. 3 finishing hot rolling mill, now having the latest automatic system, in Chiba Works. ...
A carrier-free radioiodinated phenylazide derivative of forskolin, 3-iodo-4-azidophenethylamido-7-O-succinyl-deacetyl-forskolin (({sup 125}I)IAPS-forskolin), has been shown to be a highly selective photoaffinity probe for the human erythrocyte glucose transported and the glucose transport proteins found in several mammalian tissues and cultured cells where the glucose transport protein is present at a low concentration. The photoincorporation of ({sup 125}I)IAPS-forskolin into these glucose transporters was blocked by D- (but not L-) glucose, cytochalasin B, and forskolin. In addition to labeling the mammalian glucose transport proteins, ({sup 125}I)IAPS-forskolin also labeled the L-arabinose transporter from E. coli. In muscle and adipose tissues, glucose transport is markedly increased in response to insulin. ({sup 125}I)IAPS-forskolin was ...
A carrier-free radioiodinated phenylazide derivative of forskolin, 3-iodo-4-azidophenethylamido-7-O-succinyl-deacetyl-forskolin (["1"2"5I]IAPS-forskolin), has been shown to be a highly selective photoaffinity probe for the human erythrocyte glucose transported and the glucose transport proteins found in several mammalian tissues and cultured cells where the glucose transport protein is present at a low concentration. The photoincorporation of ["1"2"5I]IAPS-forskolin into these glucose transporters was blocked by D- (but not L-) glucose, cytochalasin B, and forskolin. In addition to labeling the mammalian glucose transport proteins, ["1"2"5I]IAPS-forskolin also labeled the L-arabinose transporter from E. coli. In muscle and adipose tissues, glucose transport is markedly increased in response to insulin. ["1"2"5I]IAPS-forskolin was shown to ...
BackgroundThe equal headway instability phenomenon is pervasive in public transport systems. This instability is characterized by an aggregation of vehicles that causes inefficient...Full Text Available
The Transportation Energy Data Book: Edition 12 is a statistical compendium prepared and published by Oak Ridge National Laboratory under contract with the Office of Transportation Technologies in the Department of Energy. Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. Each of the major transportation modes--highway, air, water, rail, pipeline--is treated in separate chapters or sections. Chapter 1 compares US transportation data with data from seven other countries. Aggregate energy use and energy supply data for all modes are presented in Chapter 2. The highway mode, ...
We have investigated the transport of tritiated indole-3-acetic acid (IAA) in intact, red light-grown maize (Zea mays) coleoptiles during gravitropic induction and the subsequent development...Full Text Available
The transport of arginine into isolated barley (Hordeum vulgare L.) mesophyll vacuoles was investigated. In the absence of ATP, arginine uptake was saturable with a Km...Full Text Available
1. The short duration cerebrovascular perfusion method for measuring permeability of the blood-brain barrier has been adapted to measuring transport into the retina. 2. The method has been characterized...Full Text Available
Three flocks raised for broiler or roaster performance tests were studied to determine the incidence and sources of salmonellae during the growing period, transport and processing and to relate these...Full Text Available
Irritable bowel syndrome is a frequent gastrointestinal disorder of unknown etiology. The serotonin transporter regulates the intensity and duration of serotonin signaling in the gut and is,...Full Text Available
Amino acid transport in membrane vesicles of Bacillus stearothermophilus was studied. A relatively high concentration of sodium ions is needed for uptake of L-alanine (Kt = 1.0 mM) and L-leucine (Kt...Full Text Available
The length polymorphism of the serotonin (5-HT) transporter gene promoter region has been implicated in altered 5-HT function and, in turn, neuropsychiatric illnesses, such as anxiety and depression....Full Text Available
The rate-limiting step in the transit of dietary fat across the intestinal absorptive cell is its exit from the endoplasmic reticulum (ER) in a specialized ER-to-Golgi transport vesicle, the prechylomicron...Full Text Available
The DUR3 gene, which encodes a component required for active transport of urea in Saccharomyces cerevisiae, has been isolated, and its sequence has been determined. The deduced DUR3 protein profile...Full Text Available
We investigated the effect of irradiation on the kinetic characteristics of amino acid and glucose transport, and the effect on the activity of the cell membrane-bound enzyme 5'-nucleotidase and on the receptor-mediated stimulation of cyclic adenosine monophosphate synthesis by prostaglandin E1. Irradiation inhibited the sodium-dependent amino acid transport by a reduced binding of the amino acid to the transport unit. The transport of glucose, which appeared to be a sodium-independent process, was temporarily stimulated by increased maximal velocity of the transport. No effect was found on the binding to the transport unit. Irradiation increased the 5'-nucleotidase activity and decreased the prostaglandin E1-stimulated cyclic adenosine monophosphate synthesis 48 h after exposure to 20 Gy. It is concluded that irradiation decreases ...
Geological clay formations are investigated for use as final underground deposit for heat producing nuclear waste. Special kinds of clay (e.g. bentonite) can also be used for the construction of geotechnical barriers. For the long time safety prognosis of the nuclear waste repositories the development of geochemical transport models is indispensable. The transport of aqueous solutions in clay is a complex process. The three-layer-minerals bentonite and illite swell by the adsorption of water, if the volume is restricted a high swelling pressure develops. The excellent barrier effect of natural clay formations and geotechnical clay barriers is based on the high swelling pressure and the high adsorption capacity for radionuclides and other pollutants. The two-layer-mineral kaolinite has no swelling capacity. In contrast to sandy layers a special geochemical transport potential exists in clay besides the well known matrix ...
Three homeologous genes encoding a sucrose (Suc) transporter (SUT) in hexaploid wheat (Triticum aestivum), TaSUT1A, 1B, and 1D, were...Full Text Available
A rapid filtration technique has been used to measure at room temperature the kinetics of ADP and ATP transport in rat heart mitochondria in the millisecond time range. Transport was stopped by cessation of the nucleotide supply, without the use of a transport inhibitor, thus avoiding any quenching delay. The kinetics of ({sup 14}C)ADP transport in energized mitochondria were apparently monophasic. The rate of transport of ({sup 14}C)ATP in energized mitochondria was 5-10 times lower than that of ({sup 14}C)ADP. Upon uncoupling, the rate of ({sup 14}C)ATP uptake was enhanced, and that of ({sup 14}C)ADP uptake was decreased. However, the two rates did not equalize, indicating that transport was not exclusively electrogenic. Transport of ({sup 14}C)ADP and ({sup 14}C)ATP by resting mitochondria followed biphasic kinetics. Depletion of ...
We studied multi-joint coordination during tasks of transporting real and imaginary objects with two arms. One of the arms was unexpectedly arrested in one third of trials performed. In the...Full Text Available
This study addresses the mechanism of transport of the H2-receptor antagonist, cimetidine, by the human placenta. A 4-h recycling perfusion of a single placental cotyledon of normal, term, human placenta...Full Text Available
Hereditary hypouricemia may result from mutations in the renal tubular uric acid transporter URAT1. Whether mutation of other uric acid transporters produces a similar phenotype is unknown. We studied...Full Text Available
We analyze transport through conical channels due to the difference in particle concentration on the two sides of the membrane. Because of the detailed balance, fluxes of non-interacting particles...Full Text Available
The interfacial area transport equation dynamically models the two-phase flow regime transitions and predicts continuous change of the interfacial area concentration along the flow field. Hence, when employed in the numerical thermal-hydraulic system analysis codes, it eliminates artificial bifurcations stemming from the use of the static flow regime transition criteria. Accounting for the substantial differences in the transport phenomena of various sizes of bubbles, the two-group interfacial area transport equations have been developed. The group 1 equation describes the transport of small-dispersed bubbles that are either distorted or spherical in shapes, and the group 2 equation describes the transport of large cap, slug or churn-turbulent bubbles. The source and sink terms in the right-hand-side of the transport equations have been established by ...
ObjectivesThe expected result of the proposed research will be a complete technique for taking the decision maker through the complex process of determining what type types of flexibly delivered public transport service - if any - suits their requirements, and what service characteristics are best adapted to the constraints of their operating environment. To summarise, the objectives are to:~%~ Investigate the various factors which influence the development of an appropriate public transport system for ar [continued...]DescriptionCurrently, many statutory authorities and public transport operators are experimenting with or considering flexibly delivered public transport systems, now generally referred to as Demand Responsive Transport (DRT) services, mainly with a view to improving social inclusion in rural and urban areas that are difficult to cover by conventional public ...
A balanced application of chemiosmosis to plant mitochondria is presented. Electron transport carriers are sequenced to achieve proton translocation across the inner membrane. The processes of proton translocation, use, and release are integrated to yield a description of the effective proton gradient available for metabolite transport and ATP synthesis. 27 references, 6 figures.
Amino acid transport was studied in membranes of the peptidolytic, thermophilic, anaerobic bacterium Clostridium fervidus. Uptake of the negatively charged amino acid L-glutamate, the neutral amino...Full Text Available
In the safety assessment of a potential repository for spent nuclear fuel, it is important to assess the consequences of a hypothetical leak of radionuclides through the seabed and into a waterborne transport phase. Radionuclides adsorbed to sediment particles may be transported great distances through the processes of sedimentation and resuspension. This study investigates the transport patterns of sediment particles of two different sizes, released in the Forsmark and Laxemar area. The results show that the closed waters around Forsmark to a higher degree makes the particles stay in the area close to the release points
... operation, experimental data reduction, and application of PES results to studies related to estuarine and coastal sediment transport problems are ...
The radiative transport problem is cast in integral form using a transport kernel. The transport kernel has an explicit representation in terms of a Feynman Path Integral over all paths between selected points in a volume. This representation is setup in detail. Numerical evaluation of this Path Integral is formulated with a Frenet-Serret based procedure for generating valid random paths, and with a numerical evaluation of the weight for each valid path. Very early sanity checks of a numerical implementation are reported. Approaches to optimization are identified. (authors)
A low power polychromatic beam of microwaves is used to diagnose the behavior of turbulent fluctuations in the core of the JT-60U tokamak during the evolution of the internal transport barrier. A continuous reduction in the size of turbulent structures is observed concomitant with the reduction of the density scale length during the evolution of the internal transport barrier. The density correlation length decreases to the order of the ion gyroradius, in contrast to the much longer scale lengths observed earlier in the discharge, while the density fluctuation level remain similar to the level before transport barrier formation.
The requirements for transporting high-current, negative-ion beams are presented with particular emphasis on applications involving negative-hydrogen-ion beams. In addition to the usual matching and steering problems, particular attention must be paid to beam emittance growth in the transport system. Depending on the application, a number of approaches have been developed using both magnetic and electric lenses. I discuss the design considerations for transporting and matching these beams to radiofrequency quadrupole accelerators, and present a survey of the various types of beamlines now used for negative-ion beams.
The requirements for transporting high-current, negative-ion beams are presented with particular emphasis on applications involving negative-hydrogen-ion beams. In addition to the usual matching and steering problems, particular attention must be paid to beam emittance growth in the transport system. Depending on the application, a number of approaches have been developed using both magnetic and electric lenses. I discuss the design considerations for transporting and matching these beams to radio-frequency quadrupole accelerators, and present a survey of the various types of beamlines now used for negative-ion beams.
The requirements for transporting high-current, negative-ion beams are presented with particular emphasis on applications involving negative-hydrogen-ion beams. In addition to the usual matching and steering problems, particular attention must be paid to beam emittance growth in the transport system. Depending on the application, a number of approaches have been developed using both magnetic and electric lenses. I discuss the design considerations for transporting and matching these beams to radiofrequency quadrupole accelerators, and present a survey of the various types of beamlines now used for negative-ion beams.
... POVs) overseas when space was available. ... information management system launched in 2004. ... Personally Procured Transportation (PPT) system ...
Information that describes the use of the Otto cycle engines in transportation is summarized. The transportation modes discussed in this report include the following: automobiles, light trucks, heavy trucks, marine, recreational vehicles, motorcycles, buses, aircraft, and snowmobiles. These modes account for nearly 100% of the gasoline and LPG consumed in transportation engines. The information provided on each of these modes includes descriptions of the average energy conversion efficiency of the engine, the capital stock, the amount of energy used, and the activity level as measured in ton-miles. Estimates are provided for the years 1980 and 2000.
A brief review is presented of transport in the boundary region of magnetized plasmas by blob-like filaments. Such structures have enhanced levels of particles and heat, are elongated along the magnetic field lines and are localized in the drift plane across the field. The motion of an isolated blob structure is described in some detail and the contribution of such filaments to turbulence-driven transport are discussed. Results are presented from numerical simulations and probe measurements in tokamak plasmas. An interpretation is given of the measured dependence of particle density and transport on experimental control parameters in the scrape-off layer. (author)
The analysis of plasma density oscillations and ExB rotation of U-3M torsatron plasma was performed by UHR correlation reflectometry during the transport barrier formation. The connections between these characteristics and the phenomenon of inner and edge transport barrier formation were determined experimentally at the different values of HF power and plasma density.
The effect of open pit mine motor transport with ICE on the air basin is examined using the example of shale mines and open pits of the production association ''Estonslanets''. Efficient areas of use of different types of open pit mine motor transport, diesel-trolley tracks and electric cars are determined based on technical-economic and ecologic feasibility.
The transport of Rn through activated charcoal was modelled for a charcoal canister used for surface emanation measurements. Derived Rn concentration distributions in full and half charcoal charges were compared with measured Rn profiles. The distributions were also compared with an empirical expression for the measured profiles. Close agreement was observed between the measured, empirically generated and derived profiles. The influence of temperature and humidity on Rn accumulation and transport is also discussed.
The retina-specific ATP-binding cassette (ABC) transporter, ABCA4, is essential for transport of all-trans-retinal from the rod outer segment discs in the retina and is associated with...Full Text Available
Within the EU-Project VOTALP (Vertical Ozone Transports in the Alps), we have shown that deep alpine valleys like the Mesolcina Valley very efficiently transport air out of the polluted valley up to altitudes between 2000 and near 4000 m asl (above sea level). Pollutants emitted in these valleys are very efficiently transported up to high altitudes. (author) 2 figs., 1 tab., 2 refs.
The effect of 10 wk endurance swim training on 3-O-methylglucose (3-MG) uptake (at 40 mM 3-MG) in skeletal muscle was studied in the perfused rat hindquarter. Training resulted in an increase of approximately 33% for maximum insulin-stimulated 3-MG transport in fast-twitch red fibers and an increase of approximately 33% for contraction-stimulated transport in slow-twitch red fibers compared with nonexercised sedentary muscle. A fully additive effect of insulin and contractions was observed both in trained and untrained muscle. Compared with transport in control rats subjected to an almost exhaustive single exercise session the day before experiment both maximum insulin- and contraction-stimulated transport rates were increased in all muscle types in trained rats. Accordingly, the increased glucose transport capacity in trained muscle was not due to a residual effect of the last ...
The Lawrence Livermore National Laboratory (LLNL) is establishing a local chapter of the University of California Energy Institute (UCEI). In order to most effectively contribute to the Institute, LLNL sponsored a workshop on energy and environmental issues in transportation. This workshop took place in Livermore on August 10 and brought together researchers from throughout the UC systems in order to establish a joint LLNL-UC research program in transportation, with a focus on energy and environmental impacts.
An interpretive theory of trace impurity transport in tokamaks is presented. It is based on an earlier phenomenological approach developed by the authors for describing tokamak plasma transport experiments. The present model is used to explain disparate phenomena observed in ALCATOR C and DITE in a unified phenomenological framework. Predictive numerical calculations are presented for DITE conditions. If experimentally confirmed, the model could be used to correlate plasma properties with trace impurity behaviour. (orig.)
In order to evaluate postclosure off-site doses from low-level radioactive waste disposal facilities, a computer code was developed to simulate the radionuclide released from waste form, transport through vadose zone and transport in the saturated zone. This paper describes the methodology used to model these process. The radionuclide released from the waste is calculated using a model based on first order kinetics and the transport through porous media was determined using semi-analytical solution of the mass transport equation, considering the limiting case of unidirectional convective transport with three-dimensional dispersion in an isotropic medium. The results obtained in this work were compared with other codes, showing good agreement. (author)
The objective of this research is to replace the current flow regime dependent interfacial area correlations in the thermal-hydraulic system analysis codes with an interfacial area transport equation, which dynamically models two-phase flow regime transitions. The interfacial area transport equation applicable to bubbly flows has been developed based on mechanistic modeling of bubble interaction. Detailed experiments have been performed for bubbly conditions in 2.54, 5.08 and 10.16-cm ID pipes to benchmark the model. This new approach predicts the continuous changes of the interfacial area and will eliminate artificial bifurcations stemming from the use of the static flow regime transition criteria. This paper presents the preliminary results of incorporating the one-group transport equation into the USNRC consolidated code, currently under development. The framework for the two-group transport equation ...
This volume contains papers delivered at a technical conference of the American Society of Civil Engineers held on June 25-27, 1991 in Seattle, Washington. The conference dealt with the physical aspects of sediment processes in the coastal environment. The papers are presented under three general themes: fundamentals of coastal sediment transport, coastal geologic processes, and engineering applications. The topics of the role of long waves in coastal sediment processes and cross-shore transport are highlighted. Examples of the topics covered include: sediment transport; beach and nearshore sedimentation; shoreline and beach profile changes; longshore and cross-shore transport; storm erosion; inlet sediment processes; gravel transport; coastal structure and sediment interaction; and dredging.
NFAT involvement in adipocyte physiological processes was examined by treatment with CsA and/or GSK3{beta} inhibitors (Li{sup +} or TZDZ-8), which prevent or increase NFAT nuclear translocation, respectively. CsA treatment reduced basal and TNF{alpha}-induced rates of lipolysis by 50%. Adipocytes preincubated with Li{sup +} or TZDZ-8 prior to CsA and/or TNF{alpha}, exhibited enhanced basal rates of lipolysis and complete inhibition of CsA-mediated decreased rates of lipolysis. CsA treatment dramatically reduced the mRNA levels of adipocyte-specific genes (aP2, HSL, PPAR{gamma}, ACS and Adn), compared with control or TNF{alpha}-treatment, whereas Li{sup +} pretreatment blocked the inhibitory effects of CsA, and mRNA levels of aP2, HSL, PPAR{gamma}, and ACS were found at or above control levels. NFAT nuclear localization, assessed by EMSA, confirmed that CsA or Li{sup +} treatments inhibited or increased ...
The next-to-leading-order (NLO) cross section for the production of heavy quarks at large transverse momenta #gamma##gamma# collision is calculated with perturbative fragmentation functions (PFF). This approach allows for a resummation of terms #propor to# #alpha#_sln(p"2/m"2) which arise in NLO from collinear emission of gluons by a heavy quark at large p or from almost collinear branching of photons or gluons into heavy-quark pairs. It is presented single-inclusive distributions in p and rapidity including direct and resolved photons for #gamma##gamma# production of heavy quarks at e"+e"-colliders and at high-energy #gamma##gamma# colliders. The results are compared with fixed- order calculation for m finite including QDC radiative corrections. The two approaches differ in the definitions and relative contributions of the direct and resolved terms, but essentially agree in their sum. The resummation of the ...
Taiwan has completed a very successful five-year industrial waste minimization (IWM) demonstration and promotion project sponsored by the government. From 1990 to 1995, the project successfully disseminated the IWM concept of pollution prevention (P2) to industries. It effectively reduced industrial waste while significantly benefitting the economy by assisting industries in implementing in-plant IWM programs. In July 1995, the second stage of the five-year IWM and ISO 14000 promotion project was initiated for further promoting the IWM, P2, and cleaner production and, in particular, coping with the upcoming international environmental management standards (ISO 14000). To assist industries in establishing an environmental management system (EMS) and accumulating related experience, an EMS pilot demonstration project of five model industries and an ISO 14001 EMS demonstration and promotion project for 22 ...
For the first time absolute total cross sections for electron-impact excitation of a multiply-charged ion have been measured using an electron-energy-loss technique. Measurements were made near threshold for the process e + Si"3"+(3s"2S_1_/_2) #-># e+Si"3"+(3p"2P_1_/_2_,_3_/_2)-8.88 eV. The 10"-"1"5 cm"2 measured cross section agrees with results of 7-state close coupling calculations to better than the #+-#20% (90% CL) total uncertainty of the measurements. Convoluting the theoretical curve with a Gaussian energy distribution indicates an energy width of 0.15 < or approx. #DELTA#E < or approx. 0.20 eV. (orig.).
The role of intracellular Ca2+ (Ca2+i) on hematopoiesis was investigated in long term bone marrow cultures using cytokines and agonists of P2 receptors. Cytokines interleukin 3 and granulocyte/macrophage colony stimulator factor promoted a modest increase in Ca2+i concentration ([Ca2+]i) with activation of phospholipase Cgamma, MEK1/2, and Ca2+/calmodulin kinase II. Involvement of protein kinase C was restricted to stimulation with interleukin 3. In addition, these cytokines promoted proliferation (20 times) and an increase in the Gr-1(-)Mac-1+ population with participation of gap junctions (GJ). Nevertheless ATP, ADP, and UTP promoted a large increase in [Ca2+]i, moderate proliferation (6 times), a reduction in the primitive Gr-1(-)Mac-1(-)c-Kit+ population, and differentiation into macrophages without participation of GJ. It is likely that Ca2+i participates as a regulator of hematopoietic signaling: moderate increases in [Ca2+]i would be ...
Summary In this study, antimicrobial activity of zein films incorporated with partially purified lysozyme and disodium ethylenediaminetetraacetic acid (Na2EDTA) has been tested on selected pathogenic bacteria and refrigerated ground beef patties. The developed films containing 700-g-cm-2 lysozyme and 300-g-cm-2 Na2EDTA showed antimicrobial activity on Listeria monocytogenes, Escherichia coli O157:H7, and Salmonella typhimurium. The application of lysozyme and Na2EDTA incorporated zein films on beef patties significantly decreased total viable counts (TVC) and total coliform counts after 5-days of storage compared to those of control patties (P-2EDTA or Na2EDTA alone significantly slowed down the oxidative changes in patties during storage (P-P-2EDTA for active packaging of refrigerated mea...
Absolute total cross sections for electron-impact excitation of the 2s"2S#->#2p"2P transition in C"3"+ were measured from 7.35 eV to 8.45 eV using the merged electron-ion-beams energy-loss technique. The results settle the discrepancy between two previous experiments using the crossed-beams fluorescence method, being in very good agreement with the older results [P. O. Taylor, D. Gregory, G. H. Dunn, R. A. Phaneuf, and D. H. Crandall, Phys. Rev. Lett. 39, 1256 (1977)] but less so with the more recent ones [D. W. Savin, L. D. Gardner, D. B. Reisenfeld, A. R. Young, and J. L. Kohl, Phys. Rev. A 51, 2162 (1995)]. The present measurements are also in good agreement with unitarized Coulomb-Born and close-coupling calculations. copyright 1998 The American Physical Society.
We describe the PBAR balloon-borne magnet spectrometer flown on August 13-14, 1987 to measure the abundance of cosmic ray antiprotons in the energy interval 100-1580 MeV at the top of the atmosphere. The limits first reported have been improved to an overall limit of anti p/p<2.0x10{sup -5} (85% CL). We summarize the overall design and performance of the PBAR spectrometer, which had the unique ability to establish the mass of each singly charged cosmic ray, as well as to reject spurious antimatter candidates caused by hard scatterings within the instrument. (orig.).
The aim of the present is to consider the influence of pr equilibrium processes on the activation cross-sections of "2"7 Al(n,p) "2"7 Mg, "5"1 V(n,p) "5"1"m Ti, "8"8 Sr(n,p) "8"8"m Rb, "9"4 Zr(n,p) "9"4"m Y and "9"7"Mo(n,p) "9"7"m Nb in the neutron energy range 13 to 15 MeV. Comparison with recent measurements is given for all considered isotopes. 2 figs., 1 tab.
The #pi#g_9_/_2 band structure in "1"2"1Cs is obtained. The experiment was performed at the HI-13 MV tandem accelerator of China Institute of Atomic Energy. The excited states of "1"2"1Cs were populated via the reaction "1"1"2Sn("1"2C, p2n). The #gamma#-#gamma# coincidence data were taken with five BGO-AC HpGe detectors at beam energy of 60 Mev. The energy-level schemes of "1"2"1Cs is presented.
In this paper a comparison between calculations of severe accidents occurred from WWER-1000 with ASTEC code specified for an event of full unloading with relief valves stuck opened with no hydroaccumulators intervention is presented. The purpose of the analyses provided is to present the relationship between the improvements of the actual version (ASTEC Vl.2 rev. 1) and ASTEC V1.1 p2 like: code modifications, incoming data improvements. Such discrepancies are to be examined. Case by case suggestions for ASTEC improvements are to be provided.
Crystal structure of monoclinic telluric acid ammonium phosphate (TAAP) has been studied by an X-ray diffraction method in the paraelectric phase at 333 K and in the ferroelectric phase at room temperature. It is confirmed that the space group in the paraelectric phase is P2/n. Comparison of the results between the two temperatures suggests that the plane which is made by the PO{sub 4} tetrahedron linked by hydrogen bonds has an important role for the ferroelectric phase transition. This plane is almost parallel to the direction of spontaneous polarization.
This paper examines the feasibility of returning coal mine wastes to the mined-out areas, as encouraged by PL 95-87, the ''Surface Mining Control and Reclamation Act of 1977'' (SMCRA). Reviews a National Academy of Sciences report which identified alternative backfilling methods. Presents diagram of mechanical backfilling with gravity and mechanical transport, and tables of existing underground mine waste disposal methods and a summary of technical feasibility of alternative disposal systems. Evaluated systems include gravity disposal with mechanical surface transport; gravity disposal with mechanical in-mine transport; complete mechanical disposal; mechanical disposal with gravity surface to underground transport; direct hydraulic disposal; hydraulic disposal with natural head; hydraulic disposal with artificial head; pneumatic disposal with mechanical surface ...
Twenty undergraduate students participated in an elaborative learning test to evaluate the relationship between electrical brain activity and subsequently recalled and not-recalled words. Data collected from the midline (Fz, Cz, Pz) and lateral scalp sites (F3, F4, C3, C4, P3, P4) were analysed. The difference between event-related potentials (ERPs) elicited by subsequently recalled and not-recalled words, the ERP memory effect, was evaluated for each portion (primacy, plateau and recency) of the serial-position curve (SPC). We compared peak amplitudes for the P1, N1, P2, N400, P3 and frontal positive slow wave (FPSW) components. The electrophysiological data support the hypothesis that different mechanisms underlie primacy and recency effects during free recall paradigms. There was no support for the hypothesis that an association arises between memory and the FPSW when subjects utilise elaborative learning strategies. The ...
The transport-relevant basic data recorded within the framework of a federation-wide transport data survey made in 1986 are the best-founded source at present for determining the transport volume of other radioactive materials in different economic areas of the Federal Republic of Germany. Due to the high recording rates, a sufficiently complete survey can be provided in particular with regard to the transport volume (e.g.transports/consignments/cargos, transport distance) - with the exception of transport by ship - for the ranges of application in reserach, medicine and technology. However, as regards the radiologically relevant basic data and transport modalities, the information supplied by the transporting agencies is incomplete. A table gives a comprehensive survey of type and scope of the ...
Greenhouse gas emissions from international maritime transport are exempt from liabilities under the Kyoto Protocol. Research into quantifying these emissions is ongoing, and influences policy proposals to reduce emissions. This paper presents a cargo-based analysis of fuel consumption and greenhouse gas emissions from New Zealand's international maritime transport of goods. Maritime transport moves 99.5% (by mass) of New Zealand's internationally traded products. It is estimated that 73% of visiting vessels' activity can be directly attributed to the movement of goods in and out of New Zealand. A cargo-based methodology was used to estimate that the international maritime transport of New Zealand's imports and exports consumed 2.5 million tonnes (Mt; 2.6 billion litres) of fuel during the year 2007, which generated 7.7 Mt of carbon dioxide (CO_2) emissions. Double-counting of emissions would occur if a ...
The present conference on U.S. space transportation systems development discusses opportunities for aerospace students in prospective military, civil, industrial, and scientific programs, current strategic conceptualization and program planning for future U.S. space transportation, the DOD space transportation plan, NASA space transportation plans, medium launch vehicle and commercial space launch services, the capabilities and availability of foreign launch vehicles, and the role of commercial space launch systems. Also discussed are available upper stage systems, future space transportation needs for space science and applications, the trajectory analysis of a low lift/drag-aeroassisted orbit transfer vehicle, possible replacements for the Space Shuttle, LEO to GEO with combined electric/beamed-microwave power from earth, the National Aerospace Plane, laser propulsion to earth ...
The microbial transport simulator (MTS) is a three-dimensional, three-phase, multiple-component numerical model that permits the study of the transport of microorganisms and nutrients in porous media. Microbial parameters incorporated into MTS include: Microbial growth and decay, microbial deposition, chemotaxis, diffusion, convective dispersion, tumbling, and nutrient consumption. Governing equations for microbial and nutrient transport are coupled with continuity and flow equations under conditions appropriate for a black oil reservoir. The model`s mathematical formulations and preparation procedures of data files for conducting simulations using MTS are described. A general background of microbial transport simulation is given in Section I and the governing equations, mechanisms, and numerical solutions of MTS are given in Section II. Explanations for preparing an input data file with reservoir and ...
In the Fourth Dutch National Environmental Outlook (NMP, abbreviated in Dutch) of the National Institute of Public Health and the Environment (VROM), published in July 1997, possible future developments in the traffic and transport sector in the Netherlands are described for the period 1995-2020 and also evaluates present Dutch policies. NMP-4 also offers possible solutions for expected environmental problems. This report serves as a background document for the traffic and transport sector. With a view to present Dutch policies, the main conclusions drawn from the Outlook are that: (1) the policy targets for car and lorry use for 2010 will not be met, (2) the target for CO2 emissions from road transport for 2010 will not be met, (3) the NOx emission target for 2010 will be met for cars, but not for trucks, (4) the VOC emission target for 2010 will be met for cars, but not for trucks, and (5) the noise targets for road ...
More than 30 environmental concerns were analyzed for the transportation of coal by rail, roads (trucks), high voltage transmission lines (that is, from mine-mouth generating plants to distribution networks), coal slurry pipelines, and barges. The following criteria were used to identify these problems: (1) real physical environmetal impacts for which control technologies must be developed, or regulation made effective where control technologies presently exist; (2) the level of impact is uncertain, although the potential impact may be moderate to high; (3) the concerns identified by the first two criteria are specific to or exacerbated by coal transportation. Generic transportation problems are not included. The significant environmental problems identified as a result of this study are: (1) rail transport - community traffic disruption and human health, safety, and habitat destruction; (2) coal haul ...
The Transportation Legislative Database (TLDB) is an on-line information service containing detailed information on legislation and regulations regarding the transportation of radioactive materials in the United States. The system is dedicated to serving the legislative and regulatory information needs of the US Department of Energy and other federal agencies; state, tribal, and local governments; the hazardous materials transportation industry; and interested members of the general public. In addition to the on-line information service, quarterly and annual Legal Developments Reports are produced using information from the TLDB. These reports summarize important changes in federal and state legislation, regulations, administrative agency rulings, and judicial decisions over the reporting period. Information on significant legal developments at the tribal and local levels is also included on an as-available basis. ...
The cellular transport systems and the transport kinetics of ["1"2"3I]IMT uptake into non-malignant extracranial cells were characterized for the first time. Human fibroblasts were chosen as non-malignant extracranial cells as they are found ubiquitous in the body. ["1"2"3I]IMT is exclusively transported into fibroblasts via the sodium independent system L. An apparent Michaelis constant K_m=116.2#+-#18.9 #mu#M and a maximum transport velocity V_m_a_x=191.6#+-#13.9 pmol * (10"6 cells)"-"1 * min"-"1 were calculated for the sodium-independent transport. These results were compared with those determined in two malignantly transformed extracranial cell lines, the human Ewing's sarcoma cell lines VH-64 and CADO-ES-1.
Volume VII of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the tritium transport model documentation. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.
The paper describes transportation cost of the nuclear off-peak power for a hydrogen production based on water electrolysis in Japan. The power could be obtainable by substituting hydropower and/or fossil fueled power supplying peak and middle demands with nuclear power. The transportation cost of the off-peak power was evaluated to be 1.42 yen/kWh when an electrolyser receives the off-peak power from a 6kV distribution wire. Marked reduction of the cost was caused by the increase of the capacity factor. (author)
The properties of a helium film on the surface of solid parahydrogen are investigated. It is shown that wetting of the solid hydrogen by the liquid helium occurs. The transport velocities along the He II film on the solid parahydrogen surface are measured in broad temperature, film height, and level difference ranges. It is shown that the transport velocity in this case has the least value as compared with its value on other substrates. The thickness of the helium-saturated film is determined on the solid hydrogen surface on the basis of the data obtained, and the value is in good agreement with the results of a computation performed within the framework of the Frenkel' theory.
A compact and energy independent solar-powered refrigeration unit was to be developed to store and transport small quantities of high-quality commodities needing refrigeration. This unit comprises the following matched components: thermo-electrical refrigerator unit, solar generator and transport equipment. The solar generator is a specially developed panel with 36 cells. This unit may best be used in human medicine, veterinary medicine, environmental protection analysis, laboratories and leisure time activities. (BWI)
Additional analyses and investigations were conducted to further define transportation system concepts that will be needed for the developmental and operational phases of an SPS program. To accomplish these objectives, transportation systems such as the Shuttle and its derivatives were identified new heavy lift launch vehicle (HLLV) concepts, cargo and personnel orbital transfer vehicles (EOTV and POTV), and intraorbit transfer vehicle (IOTV) concepts were evaluated and, to a limited degree, the program implications of their operations and costs were assessed. The results of these analyses were integrated into other elements of the overall SPS concept definition studies.
Theoretical analysis of the electric field bifurcation is made for the LHD plasma. For given shapes of plasma profiles, a region of bifurcation is obtained in a space of the plasma parameters. In this region of plasma parameters, the electric field domain interface is predicted to appear in the plasma column. The reduction of turbulent transport is expected to occur in the vicinity of the interface, inducing a internal transport barrier. Within this simple model, the plasma with internal barriers is predicted to be realized for the parameters of T{sub e}(0) {approx} 2 keV and n(0) {approx_equal} 10{sup 18} m{sup -3}. (author)
The Systems Design Study (SDS) identified technologies available for the remediation of low-level and transuranic waste stored at the Radioactive Waste Management Complex's Subsurface Disposal Area at the Idaho National Engineering Laboratory. The SDS study intentionally omitted the costs of transportation and disposal of the processed waste and the cost of decommissioning the processing facility. This report provides a follow-on analysis of the SDS to explore the basis for life-cycle cost segments of transportation, disposal, and facility decommissioning; to determine the sensitivity of the cost segments; and to quantify the life-cycle costs of the 10 ex situ concepts of the Systems Design Study.
The Systems Design Study (SDS) identified technologies available for the remediation of low-level and transuranic waste stored at the Radioactive Waste Management Complex`s Subsurface Disposal Area at the Idaho National Engineering Laboratory. The SDS study intentionally omitted the costs of transportation and disposal of the processed waste and the cost of decommissioning the processing facility. This report provides a follow-on analysis of the SDS to explore the basis for life-cycle cost segments of transportation, disposal, and facility decommissioning; to determine the sensitivity of the cost segments; and to quantify the life-cycle costs of the 10 ex situ concepts of the Systems Design Study.
With major D&D projects ongoing or being planned, and also with the daily management of radwaste from nuclear facilities, the potential role of transport packagings has often been overlooked: here will one rely essentially on drums, there several local waste processing units are built, elsewhere decommissioned facilities are cut in small bits to fit into small containers by far less efficient. The present paper proposes to illustrate how integrating a transport system from the start may influence operational choices of waste management.
Computer software for risks assessment of transportation of important freight has been developed. It incorporates models of transport accidents, including terrorist attacks. These models use, among the others, unput data of cartographic character. Geographical information system technology and electronic maps of an area are involved as an instrument for handling this kind of data. Fuzzy set theory methods as well as standard methods of probability theory have been used for quantitative risk assessment. Fuzzy algebraic operations and their computer realisation are discussed. One preliminary example of risk assessment is described. (authors)
The validity is given to the newly proposed two {delta}f method for neoclassical transport calculation, which can be solve the drift kinetic equation considering effects of steep plasma gradients, large radial electric field, finite banana width, and an orbit topology near the axis. The new method is applied to the study of ion transport with steep plasma gradients. It is found that the ion thermal diffusivity decreases as the scale length of density gradient decreases, while the ion particle flux due to ion-ion self collisions increases with increasing gradient. (author)
The dual-media approach to contaminant transport modeling has emerged over the years as a clear improvement over the conventional Fickian advection-dispersion, or single-medium model, in an increasing number of settings. Recent application to the MADE-2 tracer test at Columbus Air Force Base has extended interest to field-scale plume migration in unconsolidated sediments. Subsequent application to tritium migration from the SRS F- and H-area seepage basins within this study also demonstrated improved transport predictions.
A versatile method for estimating the characteristics of radon transport in soil is developed. The method allows the following characteristics to be estimated: depth distribution function of the soil gas radon concentration, equilibrium radon concentration in the soil air, depth at which the radon concentration reaches its equilibrium value, radon flux density from the Earth's surface, and convective radon transport velocity. The method is based on soil gas radon concentration measurements and is appropriate in the case of relatively uniform geology. (orig.)
Ion neoclassical transport with finite orbit width dynamics is calculated over whole poloidal cross section by using accurate {delta}f method which employs an improved like-particle collision operator and an accurate weighting scheme to solve drift kinetic equation. Ion thermal transport near magnetic axis shows a great reduction from its conventional neoclassical level due to non-standard orbit topology, like that of previous {delta}f simulation. On other hand, the direct particle loss from confinement region may strongly increase ion energy transport near the edge. It is found that ion parallel flow near the axis is also largely reduced due to non-standard orbit topology. In the presence of steep density gradient, ion thermal conductivity is significantly reduced, and an ion particle flux is driven by self-collision alone. (author)
Indoor air exposures to gaseous contaminants originating in soil can cause large human health risks. To predict and control these exposures, the mechanisms that affect vapor transport in near-surface soils need to be understood. In particular, radon exposure is a concern since average indoor radon concentrations lead to much higher risks than are generally accepted for exposure to other environmental contaminants. This dissertation examines an important component of the indoor radon problem: the impacts of wind on soil-gas and radon transport and entry into buildings. The research includes experimental and modeling studies of wind`s interactions with a building`s superstructure and the resulting soil-gas and radon flows in the surrounding soil. In addition to exploring the effects of steady winds, a novel modeling technique is developed to examine the impacts of fluctuating winds on soil-gas and radon transport.
We have fabricated nanometer-spaced electrodes on electron-transparent silicon nitride membranes. A thin Cr/Au layer is evaporated on the backside of the membrane which serves as a gate electrode. Using these devices, we have performed three-terminal electron transport measurements on gold nano-particles at liquid helium temperature. Coulomb Blockade features have been observed and the capacitance to the gate has been extracted. After transport measurements, the Cr/Au back gate is removed and the devices are inspected with a transmission-electron microscope (TEM). TEM inspection reveals the presence of a few nano-particles in the nanogap, which is in agreement with the transport measurements. In addition, the nano-particle size as observed by TEM coincides with the one estimated from the gate capacitance value.
... Chem. Res., in press, 2006. 8. Smith, BL, Bruno, TJ, Advanced distillation curve measurement with a model predictive temperature controller. Int. ...
The utilization of thermal fluctuations or Johnson/Nyquist noise as a spectroscopic method to determine transport properties in conductors or semiconductors is developed. The autocorrelation function is obtained from power spectral density measurements thus enabling electronic transport property calculation through the Green-Kubo formalism. This experimental approach is distinct from traditional numerical methods such as molecular dynamics simulations, which have been used to extract the autocorrelation function and directly related physics only. This work reports multi-transport property measurements consisting of the electronic relaxation time, resistivity, mobility, diffusion coefficient, electronic contribution to thermal conductivity and Lorenz number from experimental data. Double va...
SummaryMammalian iron homeostasis is regulated by the interaction of the liver-produced peptide hepcidin and its receptor, the iron transporter ferroportin. Hepcidin binds to...Full Text Available
HLW disposal is one of the largest issue to utilize Nuclear power safely. In the past study, the concept, which buffer materials and Overpacked waste were transported into underground respectively, have shown. The concept of pre-assembled engineered barrier has advantage to simplify the logistics and emplacement procedure, however there are difficulties to support heavy weight of pre-assembled package by equipment under the condition of little clearance between tunnel and package. In this study, Combination of air bearing and two degree-of-freedom wheels were suggested for transportation, and air jack was suggested for unloading and emplacement system. Also, whole system for transportation and emplacement procedure was designed, and Scale model test was examined to evaluate the feasibility of these concept and functions. (author)
"Report of the Ad Hoc Subpanel on Reusable Launch Vehicle Technology. ... The author comments that the United State's space transportation system is ...
Abstract Many solute carrier transporters that interact with anticancer agents and contribute to their pharmacokinetics have been shown to be differentially upregulated in cancer cells as a result of adaptive response to altered nutritional requirements. This review focuses on pathophysiological function of membrane transporters responsible for the influx of physiological substances including oligopeptides, amino acids, and organic cations and anions, and summarizes the recent knowledge regarding mechanisms in their gene expressions. Broad substrate specificity of enhanced oligopeptide H+/peptide cotransporter 1 activity in cancer cells is useful for tumor tissue-specific delivery of chemotherapeutic agents and positron emission tomography diagnostic probes. Amino acid transporters such as...
The oviduct is an exquisitely designed organ that functions in picking-up ovulated oocytes, transporting gametes in opposite directions to the site of fertilization, providing a suitable environment...Full Text Available
For coupled quantum wires and dots, tunneling effects and coherent transport for quantum computing are being studied. In 2D systems, electron-hole bilayers for exciton...
... rivers of the world, the Zaire is not an efficient transportation link because of many rapids and falls to negotiate between Kinshasa and the port city of Matadi. ...
Phospholemman (PLM), a member of the FXYD family of regulators of ion transport, is a major sarcolemmal substrate for protein kinases A and C in cardiac and skeletal muscle. In the heart, PLM...Full Text Available
The majority of Brazilian big cities served by conventional railroad systems with routes starting in the center of the URBIS, destinate them the long distances transport of passengers and cargo. Actually, these systems are being transformed to become commuter trains which join a great capacity of transportation to a much lower costs of implantation than subway ones. The most important characteristic of this train, when talking about energy consumption, is the possibility of using different kinds of explosion engines from three cycles: Diesel, mixed (Diesel + Natural Gas), and Otto moved by natural gas, besides the traditional electric traction. The use of natural gas in Otto cycle engines shows itself competitive from the point of view of investments, operational costs and environmental preservation. (author). 10 refs., 1 fig
o If retaining CSRS/FERS, transferred employee will be credited with accumulated sick leave o Be reimbursed for travel, transportation, relocation costs ...
D-11. The Contractor shall pack and mark all hardware deliverable under this ... Handling, and Transportation, and/or MIL-STD-2073-1 and MIL-STD 2073-2, ...
The Bantam System Technology Project is one element of the Advanced Space Transportation Program -- a NASA initiative to reduce the cost of space launch and ...
Iron, zinc, copper and manganese are essential metals for cellular enzyme functions while cadmium, mercury and the metalloid arsenic lack any biological function. Both, essential metals, at high concentrations, and non-essential metals and metalloids are extremely reactive and toxic. Therefore, plants have acquired specialized mechanisms to sense, transport and maintain essential metals within physiological concentrations and to detoxify non-essential metals and metalloids. This review focuses on the recent identification of transporters that sequester cadmium and arsenic in vacuoles and the mechanisms mediating the partitioning of these metal(loid)s between roots and shoots. We further discuss recent models of phloem-mediated long-distance transport, seed accumulation of Cd and As and rec...
Nov 21, 2003... for the European Space Agency's Automated Transport Vehicle, a new, uncrewed station cargo vehicle targeted for launch late next year. ...
Congestive heart failure (CHF) is a leading cause of morbidity and mortality. CHF is marked by atrial and ventricular enlargement and reduced cardiac contractility, as well as an association...Full Text Available
... from a single location. The growing cities of Matadi and Boma and maritime transportation, and the potential ... known only from the Lower Congo River, between Matadi and Boma. (click...
of different transportation fuels (e.g., gasoline, diesel fuel, aviation gasoline, jet fuel, residual fuel oil). Subsequent calculations are performed to estimate the share...
activities, including the combustion of diesel fuel in heavy-duty vehicles and jet fuel in aircrafts. Current details on emissions from the transportation and other...
... non- emissive guidance and collision alert, automated transport in dynamic environments, and assembly and inspection. Foveal Vision, Autonomous Agents, ...
This article discusses three largely unrecognized aspects related to fluid movement in ocular tissues; namely, a) the dynamic changes in water permeability observed in corneal and conjunctival...Full Text Available
cellulosic biofuel volumes for consumption as transportation fuel, heating oil, or jet fuel in the U.S. in 2011. We also evaluated the production and import potential for...
and used to reduce or replace petroleum-based transportation fuel, heating oil or jet fuel). In addition, this rule includes a new regulatory provision establishing a...
The symposium reviewed the use of electronics in mining today. Subjects covered include control systems; remote sensing; telemetry; data transmission; microprocessors and transportation systems. 15 papers have been abstracted separately.
This paper has two key objectives. Firstly, using the findings from case study research undertaken in Colombo (Sri Lanka), Faisalabad (Pakistan) and Dar es Salaam (Tanzania), the paper seeks to demonstrate the importance of an appropriate regulatory framework and effective mechanisms of enforcement for sustainable urban transport systems in developing countries. Secondly, the paper highlights the critical importance of communication and co-ordination between stakeholders (defined here as transport users, providers and regulators) if regulation is to be effective. The views of poor and disadvantaged passenger groups-women, children, the elderly and disabled-are used in the paper to illustrate the importance of transport systems to their livelihoods, such as work, education, health and socia...
Many methods have been proposed for the determination of the corrosion current density from polarization curves; the two most commonly used ones are the three-point method and the curve-fitting method. The basis of these methods is a polarization equation that was derived for the complete absence of mass-transport effect or considers the cathodic partial reaction to be under complete mass-transport control. The mixed-control case has been much less investigated, even though this case may quite frequently reflect practical situations. A completely generalized polarization equation is proposed that can be used as a basis for curve-fitting data evaluation under any conditions. This equation was used to determine the error caused by the neglect of mass-transport effect in conventional data evaluation.
The interfacial area transport equation dynamically models the two-phase flow regime transitions and predicts continuous change of the interfacial area concentration along the flow field. Hence, when employed in the numerical thermal-hydraulic system analysis codes, it eliminates artificial bifurcations stemming from the use of the static flow regime transition criteria. Accounting for the substantial differences in the transport phenomena of various sizes of bubbles, the two-group interfacial area transport equations have been developed. The group 1 equation describes the transport of small-dispersed bubbles that are either distorted or spherical in shapes, and the group 2 equation describes the transport of large cap, slug or churn-turbulent bubbles. The source and sink terms in the right-hand-side of the transport equations have been established by ...
Diffusion in the extracellular space (ECS) of the brain is constrained by the volume fraction and the tortuosity and a modified diffusion equation represents the transport behavior of many molecules...Full Text Available
Understanding the processes responsible for coastal change is important for managing our coastal resources, both natural and economic. The current scientific understanding of coastal sediment transport and geology suggests that examining coastal processes at regional scales can lead to significant insight into how the coastal zone evolves. To better identify the significant processes affecting our coastlines and how those processes create coastal change we developed a Coupled Ocean-Atmosphere-Wave-Sediment Transport (COAWST) Modeling System, which is comprised of the Model Coupling Toolkit to exchange data fields between the ocean model ROMS, the atmosphere model WRF, the wave model SWAN, and the sediment capabilities of the Community Sediment Transport Model. This formulation builds upon ...
... that avenue, there would be a disruption in supply, the general ... Transportation Command is responsible not only for supplying warfighters in direct ...
Figure 23 presented detailed layout of the cooling system designed for the Mach 6 hypersonic- transport. The distribution system consisted of thin-wall ...
Computer software for risk assessment of transportation of important freight has been developed. It incorporates models of transport accidents, including terrorist attacks. These models use, among the others, input data of cartographic character. Geographic information system technology and electronic maps of a geographic area are involved as an instrument for handling this kind of data. Fuzzy set theory methods as well as standard methods of probability theory have been used for quantitative risk assessment. Fuzzy algebraic operations and their computer realization are discussed. Risk assessment for one particular route of railway transportation is given as an example. (author)
A study was conducted to determine the impacts of climate change on the transportation sector in a regional context. The purpose was to analyze potential climate change impacts on demand for freight transportation in Atlantic Canada through its association with other sectors of the regional economy. Freight transportation is designed to meet transportation demands of commodity producers who must deliver their goods to final users. Since it is a by-product of profit maximization and cost minimization by producers of all types of commodities in various sectors of the economy, this study modelled climate change impacts as productivity shocks in relevant sectors of the economy. A computerized simulation was then used to determine how the consequences of these shocks influence the demand for freight transportation. This was accomplished by collecting climate related data in Atlantic ...
Abstract Remediation of ground water containing anionic contaminants presents a great challenge. Because of its low cost, surfactant-modified zeolite (SMZ) has been studied for >10 years for potential uses as permeable barrier materials to remove anionic contaminants from water. In this study, zeolite aggregates with particle size of 3.4 to 4.8 mm were modified by hexadecyltrimethylammonium (HDTMA) bromide, a cationic surfactant, to a surfactant loading level of 80 mmol/kg and a concurrent counterion bromide loading level of 34 mmol/kg. While no retardation of chromate transport was observed for unmodified columns, a retardation factor of 60 was found for chromate transport through the SMZ columns. Slow but persistent desorption of HDTMA occurred throughout the chromate transport experimen...
Substances cross the blood-brain barrier (BBB) by a variety of mechanisms. These include transmembrane diffusion, saturable transporters, adsorptive endocytosis, and the extracellular pathways. Here,...Full Text Available
our exploration of space, in a manner with improved safety. ... a new Space Transportation System. ... Columbia launches as STS-107 on January 16, 2003. ...
... is known from the Lower Congo River basin (Matadi), from Pool Malebo (Stanley Pool) and from the ... Marine transport and oil disposal by boats and Matadi pose threats in the region. When the water ... ...
This is a short version of a scenario study concerning the possibilities to reach an Environmentally Sustainable Transport system in Sweden in a perspective of 30 years. The aim of the scenario study has been to describe one of several possible paths from today`s transport system to an environmentally adopted one. However, this does not imply that the task is to predict how such a transformation can be accomplished. The aim is rather to illustrate what such transformation require in the form of political decisions. The transformation of the transport system in to an environmentally adopted one, is primarily treated as a political problem, and a political perspective has accordingly been chosen for the study. In this English version of the scenario, the carbon dioxide problem is used to illuminate the many conflicts in goals and other problem that will attend an environmental adoption of the Swedish ...
The ASFIT (Anisotropic Source-Flux Iteration Technique) code was first developed in India about 1970 to solve the radiation transport equation represented in the form of coupled integral equations separating the spatial and energy-angular transmissions. The ASFIT code uses a nodal structure in the wavelength [lambda] domain in Compton units (CU) rather than in the energy domain. The ASFIT-VARI code is the latest version available from the Radiation Shielding Information Center. It incorporates variable dimensioning and has been adapted for use on MS-DOS personal computers using the Ryan-McFarland or Microsoft Version 5.0 FORTRAN compilers. While earlier versions used point cross sections (well suited for gamma-ray transport), the present version also allows multigroup cross sections for neutron and coupled neutron-gamma-ray transport.
A 3-D hydrodynamic dispersion model for tracer transport is developed and implemented into the TOUGH2 EOS3 (T2R3D) module. The model formulation incorporates a full dispersion tensor, based on a 3-D velocity field with a 3-D, irregular grid in a heterogeneous geological system. Two different weighting schemes are proposed for spatial average of 3-D velocity fields and concentration gradients to evaluate the mass flux by dispersion and diffusion of a tracer or a radionuclide. This new module of the TOUGH2 code is designed to simulate processes of tracer/radionuclide transport using an irregular, 3-D integral finite difference grid in non-isothermal, three-dimensional, multiphase, porous/fractured subsurface systems. The numerical method for this transport module is based on the integral finite difference scheme, as in the TOUGH2 code. The major assumptions of the tracer transport module are: (a) a tracer ...
...Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION QUALIFICATION AND CERTIFICATION OF LOCOMOTIVE ENGINEERS Dispute Resolution Procedures § 240.405 Processing qualification review petitions. (a)...
Full text of publication follows:In the current thermal-hydraulic system analysis codes using the two-fluid model, the empirical correlations that are based on the two-phase flow regimes and regime transition criteria are being employed as closure relations for the interfacial transfer terms. Due to its inherent shortcomings, however, such static correlations are inaccurate and present serious problems in the numerical analysis. In view of this, a new dynamic approach employing the interfacial area transport equation has been studied. The interfacial area transport equation dynamically models the two-phase flow regime transitions and predicts continuous change of the interfacial area concentration along the flow field. Hence, when employed in the thermal-hydraulic system analysis codes, it eliminates artificial bifurcations stemming from the use of the static flow regime transition criteria. Therefore, the interfacial area ...
This report describes the results of a large project conducted in a corporation between Statistics Denmark and the Danish National Environmental Research Institute. The main objective of the project has been to analyse the possibilities of prescribing the development in the Danish freight transport in a more appropriate and precise way than it is done by existing models. A secondary objective of the project was to develop a model based on the findings of the analysis. The intention was to be able to describe all areas of freight transport. The analysis has proven it impossible to improve the existing calculations in some areas of transport. Hence, the project has been narrowed down to focus exclusively on road freight transport. The developed model distinguishes itself from existing models by a much higher level of detail in the calculations. This enables the model to describe the structural relations ...
The possibility has been studied of oxidizing Prsup((3)) to Prsup((4)) when Prsup((3)) is added to an aqueous weakly-acid solution containing K_1_0[P_2W_1_7O_6_1H_2O] x H_2O. A sharp change in the solution colouring has been observed as a result of Prsup((3)) oxidation to Prsup((4)). The absorption spectra of solution of Prsup((4)) have been recorded and the values of the molar extinction coefficients have been determined. On storage of the solution, Prsup((4))reduces to Prsup((3)) with a half-reduction period of 0.2-0.5 hour.
Nucleotides released upon brain injury signal to astrocytes and microglia playing an important role in astrogliosis, but the participation of microglia in the purinergic modulation of astrogliosis is still unclear. Highly enriched astroglial cultures and co-cultures of astrocytes and microglia were used to investigate the influence of microglia in the modulation of astroglial proliferation mediated by nucleotides. In highly enriched astroglial cultures, adenosine-5?-triphosphate (ATP), adenosine 5?-O-(3-thio)-triphosphate (ATP?S), adenosine 5?-O-(3-thio)-diphosphate (ADP?S; 0.01?1?mM), and adenosine-5?-diphosphate (ADP; 0.1?1?mM) increased proliferation up to 382%, an effect abolished in co-cultures containing 8% of microglia. The loss of ATP proliferative effect in co-cultures is supporte...
Efficient, low-temperature conversion of infrared light into visible light (red, orange, green) is reported at single heterojunctions and undoped quantum wells of GaAs and ordered Al_xGa_1_-_xInP_2; an increase in photon energy of 700 meV is obtained. The signal originates from the high-band-gap layers and disappears only if the excitation energy is tuned below the GaAs band gap. The intensity of the up-converted photoluminescence (PL) is found to decrease significantly slower with increasing temperature than that of the regular PL and it remains observable up to 200 K. Interface-induced cold Auger processes along with the presence of trapped states for both electrons and holes in these ordered alloys account for this nonlinear mechanism. A colinear double-beam experiment confirms this. copyright 1996 The American Physical Society.
In the present contribution, the innovative in situ Raman micro-spectroscopy was applied to investigate the in vitro reactivity of various bioactive glasses. All the investigated glasses belonged to the Na2O\\K2O-CaO-P2O5-SiO2 system, but contained sensibly different percentages of network modifiers. The glasses were immersed for increasing times, up to 96h, in simulated body fluid (SBF) and in tris-buffered (TRIS) solution. In this way, two fundamental items were addressed, i.e. the effect of the glass composition and the nature of the soaking fluid on the overall reactivity. As regards the SBF, all the glasses were able to promote the formation of a hydroxyl-carbonate apatite (HCA) surface layer in very short times. The reaction rate was particularly quick for the 45S5 Bioglass and for it...
Meningococcal disease is an infection caused by Neisseria meningitidis. Genetic factors contribute to host susceptibility and progression to disease, but the genes responsible for disease development are largely unknown. We report here a genome-wide association study for host susceptibility to meningococcal disease using 475 individuals with meningococcal disease (cases) and 4,703 population controls from the UK. We performed, in Western European and South European cohorts (consisting of 968 cases and 1,376 controls), two replication studies for the most significant SNPs. A cluster of complement factor SNPs replicated independently in both cohorts, including SNPs within complement factor H (CFH) (rs1065489 (p.936DP = 2.2 ? 10?11) and in CFH-related protein 3 (CFHR3)(rs426736, P = 4.6 ...
Amplitudes for fermion-fermion, boson-boson and fermion-boson interactions are calculated in the second order of perturbation theory in the Lobachevsky space. An essential ingredient of the model is the Weinberg's 2(2j+1)-component formalism for describing a particle of spin j. The boson-boson amplitude is then compared with the two-fermion amplitude obtained long ago by Skachkov on the basis of the Hamiltonian formulation of quantum field theory on the mass hyperboloid, p_0^2 - p^2=M^2, proposed by Kadyshevsky. The parametrization of the amplitudes by means of the momentum transfer in the Lobachevsky space leads to same spin structures in the expressions of T-matrices for the fermion case and the boson case. However, certain differences are found. Possible physical applications are discussed.
Objective:EEG source imaging provides important information regarding the underlying neural activity from noninvasive electrophysiological measurements. The aim of the present study was to evaluate source reconstruction techniques by means of the intracranial electrocorticograms (ECoGs) and functional MRI.Methods:Five source imaging algorithms, including the minimum norm least square (MNLS), LORETA with Lp-norm (p equal to 1, 1.5 and 2), sLORETA, the minimum Lp-norm (p equal to 1 and 1.5; when p=2, the MNLS method is mathematically equivalent to the minimum Lp-norm) and L1-norm (the linear programming) methods, were evaluated in a group of 10 human subjects, in a paradigm with somatosensory stimulation. Cortical current density (CCD) distributions were estimated from the scalp somatosensor...
For the first time, absolute cross sections for electron-impact excitation of a multiply charged ion have been measured using an electron-energy-loss technique. Cross sections for e+Si"3"+(3s "2S_1_/_2)#->#e+Si"3"+(3p "2P_1_/_2_,_3_/_2)-8.88 eV have been measured with an accuracy of #+-#20% (at 90% confidence level) over a narrow energy range (#+-#0.6 eV) about the threshold energy with an energy resolution of 0.2 eV. Results are in good agreement with close-coupling calculations.
As a contribution to the US/Japan cooperative program in fusion neutronics, we have prepared a library of multigroup neutron cross sections, scattering matrices, and covariances (uncertainties and their correlations). This 74-group library, called COVFILS-2, is being used at Los Alamos and at the University of California at Los Angeles in the sensitivity and uncertainty analysis of the Li_2O integral experiment recently performed at the Fast Neutron Source (FNS) in Japan. Another intended use of this library is in the estimation of the uncertainty in key performance parameters (such as breeding ratio) of conceptual fusion reactors. The 14 materials included in the first version of COVFILS-2 are H, "6Li, "7Li, Be, C, N, O, Na, Al, Si, Cr, Fe, Ni, and Pb.
The U.S. Department of Energy (DOE) Office of Pollution Prevention (EM-77) created is successful internally competed program to fund innovative projects based on projected returns. This is called the Return-on-Investment (ROI) program. EM-77 conducted a successful ROI pilot, developed and implemented sound management practices, and successfully transferred the program to several Operations Offices. Over the past 4 years sites have completed 262 ROI projects (costing $18.8 million) with claimed first-year savings of $88 million and claimed life cycle savings exceeding $300 million. EM-77 requested that Oak Ridge National Laboratory perform an independent evaluation of the site-led, DOE-HQ-funded pollution prevention (P2) ROI program to assist the Department in determining whether claimed savings are real.
The excitation function of ({alpha},{ital xn}) reactions on {sup 191}Ir (abundance 37.3%) and on {sup 193}Ir (abundance 62.7%) has been measured for the 17--55 MeV alpha-particle bombarding energy range. The stacked foil activation technique and {gamma}-ray spectroscopy were used to determine the cross sections. The experimental data were compared with calculated values obtained by means of a geometry-dependent hybrid model. The initial exciton number {ital n}{sub 0}=4 with {ital n}=2, {ital p}=2, and {ital h}=0 gives the best agreements with the presently measured results. To calculate the excitation function theoretically a computer code was used. This set of excitation functions provides a data basis for probing the validity of combined equilibrium and preequilibrium reaction models in a considerable energy range.
Web Services and mobile data services are the newest trends in information systems engineering in wired and wireless domains, respectively. Web Services have a broad range of service distributions while mobile phones have large and expanding user base. To address the confluence of Web Services and pervasive mobile devices and communication environments, a basic mobile Web Service provider was developed for smart phones. The performance of this Mobile Host was also analyzed in detail. Further analysis of the Mobile Host to provide proper QoS and to check Mobile Host's feasibility in the P2P networks, identified the necessity of a mediation framework. The paper describes the research conducted with the Mobile Host, identifies the tasks of the mediation framework and then discusses the feasible realization details of such a mobile Web Services mediation framework.
In order to reduce the potential for severe liquid pipeline accidents, the U.S. Materials Transportation Bureau (MTB) proposes to require a hydrostatic test on all onshore pipelines carrying highly volatile liquids which have not been previously tested to at least 1.25 times their maximum operating pressure for at least 24 hr. Comments should be received by the MTB by 2/15/79. Late filed comments will be considered as far as practicable.
We solve an R -linear problem for a multiple-connected circular domain in a class of doubly periodic functions in analytic form by a method of functional equations. This problem models transport properties of two-dimensional composite materials made from a collection of disks embedded in an otherwise uniform host.
We solve an R -linear problem for a multiple-connected circular domain in a class of doubly periodic functions in analytic form by a method of functional equations. This problem models transport properties of two-dimensional composite materials made from a collection of disks embedded in an otherwise uniform host.
By the year 2000, the Postal Service aims to reduce its diesel transport by around 15000 vehicles. The advisory service, Detecon, is reviewing alternatives for postal deliveries as part of the ''Post 2000'' initiative. One such system is an electric-powered vehicle with a zinc-air battery from the Israeli firm Electric Fluid Limited (EFL). (orig.)
The variation of indole-3-acetic acid (IAA) transport along Lupinus albus L. hypocotyls was studied using decapitated seedlings and excised sections. To confirm that the mobile species...Full Text Available
An explicite PN solution of the multi-dimensional homogeneous neutron transport equation is given by expanding the angular flux into a series of geometry-independent spherical harmonics operators. An algorithm is developed for representing the spherical harmonic operators in orthogonal curvilinear coordinates. The general formulae are applied to two-dimensional spherical geometry; detailed P3 formulae are given. (orig.).
The purpose of the work reported in this paper was to measure the radionuclide buildup in primary heat transport system cell No. 3 at the Fast Flux Test Facility (FFTF) and to compare the results with predicted values from a model based on experimental studies and experience at similar reactors. The information obtained is used for maintenance planning and to enhance ability to assess radionuclide buildup in the future at FFTF and in other reactors.
This project (a) demonstrated specific dopamine transporter (DAT) uptake in vivo and metabolic stability of a radiolabelled cycloplentadieny rhenium compound in rats and baboons, (b) showed that cyclopentadieny tricarbonyl rhenium and technetium compounds conjugated tropanel could be made by metal transfer with ferrocenes; and (c) explored new methods of synthesizing these compounds under mild conditions.
Numerical errors of PALLAS calculation due to spatial mesh sizes are examined for a typical deep penetration shielding problem of isotropic incident fission neutrons penetrating a 200-cm-thick water slab. The exponential approximation for the source spatial distribution to solve the transport equation based on the direct integration method is verified to be effective for radiation transport in attenuating medium, while the linear approximation employed in the old PALLAS code is found to produce large errors for calculations with large mesh sizes.
In this study, we investigate an inter-industrial and inter-regional recycling system for industrial waste by the cement industry in Japan. We develop a linear programming model that represents cement production processes and waste transportation of all cement factories in Japan. We simulate cost and CO{sub 2}-minimizing systems. The result implies that making waste transportation more efficient in cost is an effective means for CO{sub 2} reduction. (author)
Microfluidic systems and methods are disclosed which are adapted to transport and lyse cellular components of a test sample for analysis. The disclosed microfluidic systems and methods, which employ an electric field to rupture the cell membrane, cause unusually rapid lysis, thereby minimizing continued cellular activity and resulting in greater accuracy of analysis of cell processes.
This paper reports a recent feasibility study of a scheme to transport thermal coal as a coal-water slurry by pipeline from Coalspur, Alberta to the west coast of Canada. The base case is for the transport of 10.2 million tons of coal annually, and an expanded case of 18.2 million tons is also considered. Coal would be drawn from 5 mines within a 16 km radius of Coalspur. Several different terminal layouts were considered.
The multidrug efflux transporter AcrAB-TolC is known to pump out a diverse range of antibiotics, including β-lactams. However, the kinetic constants of the efflux process, needed for the quantitative...Full Text Available
The yeast phosphatidylinositol transfer protein (Sec14p) is required for biogenesis of Golgi-derived transport vesicles and cell viability, and this essential Sec14p requirement is abrogated by inactivation...Full Text Available
The membrane transport of the two stable lithium isotopes, {sup 6}Li and {sup 7}Li, by erythrocytes has been studied using a dual channel atomic absorption spectroscopic technique. {sup 6}Li appears to be taken up preferentially to {sup 7}Li, in the ratio of 10 to 40%, depending on the concentration of total lithium and on the lithium isotopic ratio in the external medium.
A modified version of the osmotic shock technique was used to investigate HCO3− and OH−transport in the alga Chara corallina. Cell...Full Text Available
This paper examines the technological, socio-economic and environmental feasibility of a proposal to strengthen the Italian commercial coastal shipping system as an alternative to bolstering existing road transport facilities in order to meet the requirements of increased trade in the new European free market. This prospect is of special importance to Italy due to its long coastlines. The principal elements taken into account are: investment capital, labour and energy requirements. The study first examines the supply and demand dynamics of the European transport system. Here, attention is given to energy consumption. This examination is followed by a review of the European situation with regard to normatives governing navigation and customs duties. Road, rail and maritime transport costs are compared, and an assessment is made of the economic feasibility of an integrated-means system of transport ...
The effects of purified Helminthosporium maydis T (HmT) toxin on active Ca/sup 2 +/ transport into isolated mitochondria and microsomal vesicles were compared for a susceptible (T) and a resistant (N) strain of corn (Zea mays). ATP, malate, NADH, or succinate could drive /sup 45/Ca/sup 2 +/ transport into mitochondria of corn roots. Ca/sup 2 +/ uptake was dependent on the proton electrochemical gradient generated by the redox substrates or the reversible ATP synthetase, as oligomycin inhibited ATP-driven CA/sup 2 +/ uptake while KCN inhibited transport driven by the redox substrates. Purified native HmT toxin completely inhibited Ca/sup 2 +/ transport into T mitochondria at 5 to 10 nanograms per milliliter while transport into N mitochondria was decreased slightly by 100 nanograms per milliliter toxin. Malate-driven Ca/sup 2 +/ transport in T mitochondria was ...
This report describes the 2005 version of the Fluka particle transport code. The first part introduces the basic notions, describes the modular structure of the system, and contains an installation and beginner's guide. The second part complements this initial information with details about the various components of Fluka and how to use them. It concludes with a detailed history and bibliography.
The effect of a number of dietary and synthetic chelating agents on the intestinal absorption of lead has been examined using the everted sac preparation and the tracer isotope /sup 203/Pb. All the agents examined increased lead transport into the serosal compartment. An explanation of the way in which these agents modify the model to describe lead transport is proposed.
The objective of this paper is to present a theoretical evaluation of soil and house related factors that may affect the transport of radon from the soil into houses. A two-dimensional mathematical model was used to simulate the diffusive and convective transport of radon into the house through idealized openings in the understructure. With the help of model predictions we tried to find out whether diffusion or convection predominates and under which circumstances. Radon transport through cracks in the house understructure is influenced mainly by the soil permeability, radon concentration at the soil-crack interface, the total area of cracks and the pressure difference across cracks. Because of its large range of variability, the soil permeability appears to have the greatest effect on the radon transport through cracks. At permeabilities below 1x10"-"1"2 m"2 diffusive transport ...
In research of nuclear medicine and development of radiopharmaceuticals, it is necessary to do data analysis and know transportation behaviors of the radionuclide in tissues or organs concerned. Based on polynomial fitting method, we developed the software INDFIT 1.0 programmed by Microsoft Visual Basic 6.0 (VB 6) for the data analysis. Experimental calculations showed that the software was of practical use
Recent experiments have explored the use of a free-electron laser (FEL) as a buncher for a microwave two-beam accelerator, and the subsequent driving of a standing-wave rf output cavity. Here the authors present a deeper analysis of the longitudinal dynamics of the electron bunches as they are transported from the end of the FEL and through the output cavity. In particular, the authors examine the effect of the transport region and cavity aperture to filter the bunched portion of the beam.
The effect of finite gyroradius on the current diffusive ballooning mode is examined. Starting from the reduced MHD equations including turbulent transports, coupling with drift motion and finite gyroradius effect of ions, we derive a ballooning mode equation with complex transport coefficients. The eigenfrequency, saturation level and thermal diffusivity are evaluated numerically from the marginal stability condition. Preliminary results of their parameter dependence is presented. (author)
A new nonlinear S{sub n} transport differencing scheme for slab geometry is presented that is fourth order accurate for small meshes and is strictly positive. The new scheme has been coded into the existing ONELD code and tested. Numerical results to demonstrate the accuracy and positivity of this new scheme are presented.
The bioenergetic capacity of skeletal muscle in a 17-year-old patient with a severe defect in complex III of the electron transport chain has been examined by 31P NMR measurements of the molar ratio...Full Text Available
Ammonia borane (AB) and sodium borohydride (SBH) are candidate materials for on-board hydrogen storage that can be dehydrogenated upon demand. The rheological properties of the dehydrogenated by-products are important to quantify their removal and transportability from the hydrogen storage system. This paper presents visco-elastic property (elastic stiffness and viscous damping) measurements of the spent fuels obtained from AB hydrolysis, hydrothermolysis and thermolysis; and SBH hydrolysis. Smaller stiffness and larger mobility (or smaller viscous damping) indicate better transportability of the spent fuel. In addition, flow property (dynamic angle of repose and avalanching time) measurements for the hydrolysis spent fuels of AB and SBH are also presented. Comparing with the SBH hydrolysis spent fuel, the AB hydrolysis spent fuel had a lower stiffness and larger mobility, as well as lower angles of dynamic repose and avalanche power peaks, ...
The transport properties of a 'thin' polycrystalline diamond film are analyzed after the sample exposure to 8.06-keV x-ray radiation. Structure and morphology of the as-grown film have been evaluated by Raman, x-ray diffraction, and scanning electron microscopy techniques. The transport properties have been investigated by measuring dark current-voltage characteristics in the temperature range of 60 to 360 K. Ohmic transport has been evidenced on the as-grown film up to 1.16x10"5 V/cm. After irradiation, nonlinear contributions to the dark current have been evidenced and related to field-assisted thermal ionization of traps. Below 200 K, hopping mechanisms have been observed. Correlations have been found among x-ray irradiation, density of traps involved in the transport processes, and the nonhomogeneous nature of the sample. A simple model of the grain boundary structure is proposed to explain the ...
The NRL Long Pulse Induction Linac is being employed in a Free Electron Laser (FEL) experiment. The authors present results of beam transport and focusing experiments as well as measurements of the output radiation generated by various magnetic wigglers. The electron gun of the accelerator presently has a 17-cmdiam. cold cathode which is located in a nearly zero magnetic field (B /SUB z/ less than or equal to 5 G). The gun voltage is flat to within approx. = + or - 5% for 1.5 #mu#sec with this graphite brush cathode. The beam is focused by a series of solenoidal coils as it propagates through the 4-m-long accelerator."2 A solenoidal field which can be varied from 1-10 kG confines the beam in the FEL interaction region. Previous experiments were limited by poor beam transport, focusing, and matching into the relatively large solenoidal field in the FEL region. By smoothing the axial magnetic field profile in the accelerator and making a more ...
Different concrete waste packages have been designed by Electricite de France (EDF) for the long-term storage of radioactive Low Level Waste (LLW). Their main function is to confine radionuclides from the biosphere for three hundred years in a near-surface disposal. According to the transport regulations, a Type-B package is needed for some waste like water filters. The water filters from EDF nuclear power plants are encapsulated in mortar and placed in a concrete container. Transport regulations for these containers have required the development of a methodology for safety assessment. The reference scenario of container degradation during transport considers a 9 m drop and a 800"oC fire for 30 min. First, the different chemical and physical processes involved in the containment of radionuclides are analysed. In particular, the radionuclide transport mechanisms in cement-based materials have been ...
Development of the engineering technology basis of pyrometallurgical reprocessing is a key issue for industrialization. For development of the transport technologies of molten salt and liquid cadmium at around 500 deg. C, a salt transport test rig and a metal transport test rig were installed in Ar glove box. Function of centrifugal pump and 1/2'' declined tubing were confirmed with LiCl- KCl molten salt. The transport behavior of molten salt was found to follow that of water. Function of centrifugal pump, vacuum sucking and 1/2'' declined tubing were confirmed with liquid Cd. With employing the transport technologies, industrialization applicable electro-refiner was newly designed and engineering-scale model was fabricated in Ar glove box. The electro-refiner has semi-continuous liquid Cd cathode instead of conventional one used in small-scale tests. With using actinide-simulating ...
A numerical model of multiphase air-water flow and contaminant transport in the unsaturated zone is presented. The multiphase flow equations are solved using the two-pressure, mixed form of the equations with a modified Picard linearization of the equations and a finite element spatial approximation. A volatile contaminant is assumed to be transported in either phase, or in both phases simultaneously. The contaminant partitions between phases with an equilibrium distribution given by Henry`s Law or via kinetic mass transfer. The transport equations are solved using a Galerkin finite element method with reduced integration to lump the resultant matrices. The numerical model is applied to published experimental studies to examine the behavior of the air phase and associated contaminant movement under water infiltration. The model is also used to evaluate a hypothetical design for a low-level radioactive waste disposal ...
A plan to diffuse instructional modules for the preparation of transportation professionals is presented, based on research and demonstration projects sponsored by the Urban Mass Transportation Administration (UMTA). The diffusion/adoption plan involves: developing instructional modules; disseminating the modules to professors teaching transportation courses at the college level; promoting the use and adoption of the modules; and evaluating and revising the plan. Transportation educators teach in a variety of disciplines (e.g., engineering, public administration, urban planning, and technology). Eight design and evaluation criteria for the instructional modules are listed, along with the procedures used by West Virginia University in developing the five instructional modules. The diffusion strategy involves repackaging UMTA research findings, change agents, and the use of information channels (e.g, ...
New platinum(II) complexes with asymmetrically substituted chiral diamine ligands A{sub 2}PtX{sub 2}, (A{sub 2}=NH{sub 2}CH(CH{sub 3})CH{sub 2}NH(c-C{sub 5}H{sub 9}) (apcpa), NH{sub 2}CH(CH{sub 3})CH{sub 2}NH(c-C{sub 6}H{sub 11}) (apcha); X{sub 2}=2Cl, isopropylidenmalonate (IPM), 1,1'-cyclobutandicarboxylate (CBDCA) have been synthesized and characterized by means of elemental analyses, infrared and NMR spectroscopies, and X-ray crystallography. The crystal structures of (S-apcha)Pt[CBDCA]{center_dot}3H{sub 2}O (orthorhombic, P2{sub 1}2{sub 1}2(No. 18), a=6.926(3), b=15.243(3), c=19.319(4) A, V=2039.5(10) A{sup 3}, Z=4, R=0.072) and (S-apcha)Pt[IPM]{center_dot}2.5H{sub 2}O (monoclinic, P2/c(No. 13), a=9.882(1), b=18.502(1), c=22.056(1) A, V=4032.8(5) A{sup 3}, Z=8, R=0.093) exhibit that the platinum atoms achieve a typical square planar arrangement with two nitrogen atoms in cis position and ...
Interleukin 2 (IL-2) is a T-cell-derived lymphokine critical in the activation and proliferation of T cells, B cells, and lymphokine-activated killer cells. It is a glycoprotein of #approx#15,500 daltons that is synthesized and secreted after activation by antigen or mitogen. By using the analogs 8-azidoadensoine 5'-[#gamma#-"3"2P]triphosphate ([#gamma#-"3"2P]8N_3ATP) and nicotinamide 2-azidoadenine [adenylate-"3"2P]dinucleotide ([#alpha#-"3"2P]2N_3NAD"+) as photoaffinity probes, the authors have detected specific, metal ion-requiring nucleotide binding sites on recombinant human IL-2 (rhIL-2). The specificity of these nucleotide interactions with rhIL-2 was demonstrated by saturation effects and by competition by the parent nucleotides at physiologically relevant concentrations. Saturation of photoinsertion into rhIL-2 occurred at 50 #mu#M [#gamma#-"3"2P]8N_3ATP. Saturation of photoinsertion with ...
An important advantage of carrying out enzymatic catalysis in organic media is the increased solubility of hydrophobic substrates. This study compares a model lipase catalyzed esterification of cholesterol using vinyl acetate (VA) in two such nontraditional media: high-pressure hexane and supercritical (SCF) ethane. The effect of using one of the reactants (VA) as a cosolvent to increase the solubility of the other reactant (cholesterol) in SCF ethane has been investigated. The thermodynamic activity of water (a(w)) in the reaction media was controlled by the direct addition of the salt hydrate pair Na(4)P(2)O(7)/Na(4)P(2)O(7).10H(2)O. The a(w) of the salt hydrate system is shown to be a function of pressure and its variation over the pressure range 104-173 bar has been estimated. The initial reaction rate in pressurized hexane was found to vary linearly with the cholesterol concentration. The reaction ...
The coal transportation industry has played an integral role in determining coal markets, particularly in recent years, as the industry has evolved from cost-based pricing to market-based pricing. Aggressive pricing by Western rail carriers has caused extensive changes in coal marketing patterns in the Midwest. Multi-modal barge deliveries of Western and Appalachian coals have also played a significant, though lesser, role in changing coal markets. Eastern rail carriers have generally lagged in their aggressive pursuit of new coal markets and, to date, few changes in coal markets have been realised. The historic dominant role of transportation in shaping markets for coal will continue into the future as the utility industry contends with the effects of CAAA compliance and deregulation and as the coal industry contends with regional coal displacements and major imbalances in supply and demand. The dominance of rail ...
On July 18, 2001, a freight train carrying hazardous (non-nuclear) materials derailed and caught fire while passing through the Howard Street railroad tunnel in downtown Baltimore, Maryland. The United States Nuclear Regulatory Commission (USNRC), one of the agencies responsible for ensuring the safe transportation of radioactive materials in the United States, undertook an investigation of the train derailment and fire to determine the possible regulatory implications of this particular event for the transportation of spent nuclear fuel by railroad. Shortly after the accident occurred, the USNRC met with the National Transportation Safety Board (NTSB), the U.S. agency responsible for determining the cause of transportation accidents, to discuss the details of the accident and the ensuing fire. Following these discussions, the USNRC assembled a team of experts from the National Institute of Standards ...
This report documents a one-dimensional numerical model, SAMFT1D, developed to simulate single-phase and multiphase fluid flow and solute transport in variably saturated porous media. The formulation of the governing equations and the numerical procedures used in the code for single-phase and multiphase flow and transport are presented. The code is constructed to handle single-phase as well as two or three-phase flow conditions using two integrated sets of computational modules. The fully implicit scheme is used in the code for both single-phase and multiphase flow simulations. Either the Crank-Nicholson scheme or the fully implicit scheme may be used in the transport simulation. The single-phase modules employ the Galerkin and upstream weighted residual finite element techniques to model flow and transport of water (aqueous phase) containing dissolved single-species contaminants concurrently or ...
Durability of 28 days compressive strength concrete of 20 to 120 MPa has been studied. The ability of concrete to transport aggressive agents has been determined for four properties: the air permeability, the chloride diffusivity, the water absorption and the carbonation. A chloride migration test for high and very high strength concrete (HSC and VHSC) has been built. The relationship between transport properties and the compressive strength after one and 28 days of humid curing has always the same shape: transport decreases when strength increases. However, transport properties often vary in the ordinary concrete field. Beyond, the domain is much more limited. The relationship between transport properties and strength valid for ordinary concrete can not be simply extrapolated for HSC and VHSC. To determine the part of microcracking of HSC and VHSC, concrete behaviour stored in two ...
Volume V of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the transport parameter and source term data. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.
Single-crystalline PbTe nanowires were synthesized using the chemical vapor transport method. They consisted of rock-salt structure PbTe nanocrystals uniformly grown in the [100] direction. We fabricated field-effect transistors using a single PbTe nanowire, providing evidence for its intrinsic n-type semiconductor characteristics. The values of the carrier mobility and concentration were estimated to be 0.83 cm"2 V"-"1 s"-"1 and 8.8 x 10"1"7 cm"-"3, respectively. The Seebeck coefficients (-72 ?V K"-"1) of individual nanowires were measured to show their n-type carrier-dominated thermoelectric transport properties.
Quark Gluon Plasma transport coefficients for heavy quarks and quark-antiquark pairs are computed through an extension of the results obtained for a hot QED plasma by describing the heavy-quark propagation in the eikonal approximation and by weighting the gauge field configurations with the Hard Thermal Loop effective action. It is shown that such a model allows to correctly reproduce, at leading logarithmic accuracy, the results obtained by other independent approaches. The results are then inserted into a relativistic Langevin equation allowing to follow the evolution of the heavy-quark momentum spectra. Our numerical findings are also compared with the ones obtained in a strongly-coupled scenario, namely with the transport coefficients predicted (though with some limitations and ambiguities) by the AdS/CFT correspondence.
Peculiarities of Kurchatov Institute WWR-2 and TR research reactors spent fuel treating and transportation for radiochemical processing are stated. Spent fuels were performed as fuel assemblies of different forms and containing similar fuel elements: EhK-10 with 10% enrichment UO2-Mg fuel kernels or S-36 with 36% enrichment U-Al alloys. Spent fuel storage conditions are described. Features of developed procedures for identification of fuel assemblies by type of fuel elements are given. Transport package TUK-19 for loading and transportation of spent fuel for processing was chosen. Details of spent fuel loading in TUK-19 that is conducted by personnel under protective sheet of water in special reclaim volume are described
For a soft-contact-lens (SCL) wearer, corneal health and comfort are strongly influenced by water transport through the polymeric materials used in lens fabrication. In particular, evaporative water loss at the anterior lens surface is a potential cause of contact-lens dehydration and of post-lens tear-film depletion, which in turn, may lead to discomfort, dryness syndrome, and/or lens adhesion.We present a solution-diffusion model for transport of water through soft-contact-lens materials to mimic evaporative dehydration from a contact lens during blinking and to access possible SCL adhesion to the corneal surface under a variety of environmental conditions (e.g., wind speed and relative humidity). To describe the water-transport process, we use an extended version of the Maxwell-Stefan m...
Analyses of pressure vessel damage resulting from neutron irradiation have primarily relied on two-dimensional transport calculations and a spatial-synthesis methodology to accommodate three-dimensional effects in the results of two two-dimensional calculations. In this paper, the authors report on calculations made on the Pool Critical Assembly (PCA) Benchmark, Configuration 12/13, using the three-dimensional, continuous energy Monte Carlo transport code, MCNP, and the three-dimensional, multigroup, diffusion accelerated discrete ordinates transport code THREEDANT. Neutron fluxes and activation rates as determined from these two calculations are compared to each other and to experimental results in the literature. The authors also draw some conclusions on the value of 3D calculations on the interpretation of experimental results.
The human erythrocyte (RBC) Rh blood group system consists of a complex of distinct integral membrane polypeptides with physical properties common to the aminophospholipid transporter responsible for the transbilayer movement of phosphatidylserine (PS) in RBC. To assess the involvement of Rh polypeptides in PS translocation, the aminophospholipid translocase was labeled with a photoactivatable PS analogue, "1"2"5I-azido-PS, and with an inhibitor of PS transport, "1"2"5I-labeled 2-(2-pyridyldithio)ethylamine. The ability of monoclonal Rh antibodies to immunoprecipitate the labeled transporter was determined. Immunoprecipitated Rh polypeptides were found to be labeled with the aminophospholipid translocase markers, suggesting that Rh proteins are involved in the transbilayer movement of PS.
Well over 90 percent of all motorized transportation is fueled by products of petroleum, but the end of such widespread use of oil may be in sight. Among alternative fuels for land transportation, electricity appears to be the most promising, in part because it can be renewably produced and readily transmitted. The inadequacy and high cost of on-board storage of electrical energy present major challenges to widespread deployment of electric traction, and may do so for many years. On-board generation of electrical energy also presents challenges. The third means of powering electric traction is to provide for connection to the electricity grid while in motion. Grid-connected vehicles (GCVs) are an established feature of many cities and of much inter-city transportation, chiefly as electric ...
Reactive chemical transport models developed over the past decade have generally relied on the assumption that local thermodynamic equilibrium is achieved at all times between aqueous species in a given system. Consequently, homogeneous aqueous systems characterized by a number of kinetically slow reactions, particularly problems involving organic species, cannot be satisfactorily modeled. In this study, we present a prototype computer model, KINETRAN, which is designed to handle kinetically-controlled homogeneous reactions in the aqueous phase, along with the transport of the various species involved, through geologic media. 31 refs., 53 figs., 10 tabs.
One of the major challenges facing the proposed high-energy linear e^+e^ colliders is the preservation of the extremely small vertical emittance from the damping rings to the interaction point (IP). This emittance must be transported through bunch compression sections, the main linac and finally through the beam delivery system to the IP. Historically, the beam dynamics issues of each subsystem have been studied quasi-independently, with the beam conditions and tolerances being specified at the boundaries. As part of the recent International Linear Collider Technical Review Committee, new simulation tools have been developed to simulate the beam transport through the integrated system, including static and dynamic errors, stabilization systems, and tuning algorithms.
Background, aim, and scope Semi-trailers with load boxes are the most important mode of grain transport by land in the world. Load boxes can be produced with different materials such as: wood, steel, and synthetic material. They are responsible for effectiveness retention and quality of grains during the transport. Among the main aspects to be considered and valued when selecting materials for load boxes are the final mass of the semi-trailer, loss of grains, and mechanical properties. Environmental performance is another important aspect to be taken into account for developing and selecting new materials in this kind of application. This study presents a comparative environmental evaluation of load boxes built from two different materials (a wood panel and a three-layer synthetic (TLS) pa...
The objective of this study is to describe the complete transport chain of CO2 between capture and storage including a ship transport. This last one is composed by the following steps:Shore terminal including the liquefaction, temporary storage and CO2 loading. Ship with a capacity of 30,000m^3. On or off shore terminal including an unloading system, temporary storage and export towards the final storage. Between all the possible thermodynamic states, the liquid one is most relevant two options are compared in the study (-50^oC, 7bar) and (-30^oC, 15bar). The ship has an autonomy of 6 days, is able to cover 1000km with a cargo of 2.5Mt/year. Several scenarios are studied varying the geographical position of the CO2 source, the number of harbours and the way the CO2 is finally stored. Depen...
Since the 1950s a transport revolution has occurred comparable to events in the late nineteenth century when sailing ships were replaced by steam vessels. Freight rates for bulk products have decreased 65-70% due to improved maritime technology, and formerly separate markets for bulk products have been unified globally. It is suggested that the low freight rates since the early 1980s will level out in future. Price peaks caused by political and military crises like the Korean war, the Suez crisis, OPEC I and OPEC II also seem to be of diminishing importance over time. The world market has become much less sensitive to external shocks due to alternative sources of supply and alternative transport routes. Examples are given from the coal, grain and iron ore international market. 62 refs., 24 figs., 4 tabs.
The solution of the governing steady transport equations for momentum, heat and mass transfer in flowing fluids can be very difficult. These difficulties arise from the nonlinear, coupled, nonsymmetric nature of the system of algebraic equations that results from spatial discretization of the PDEs. In this manuscript the authors focus on evaluating a proposed nonlinear solution method based on an inexact Newton method with backtracking. In this context they use a particular spatial discretization based on a pressure stabilized Petrov-Galerkin finite element formulation of the low Mach number Navier-Stokes equations with heat and mass transport. The discussion considers computational efficiency, robustness and some implementation issues related to the proposed nonlinear solution scheme. Computational results are presented for several challenging CFD benchmark problems as well as two large scale 3D flow simulations.
The solid particle movement in a rotary drum plays an important role in drying processes. The solid distribution in the drum affects the amount of contact surface between the solid and the gas. The retention time of solids influences the time particles can stay in contact with the gas in order to transfer heat and mass. Any heat and mass transfer model for a solid particle dryer must be able to predict solid flowrate and solid hold-up. There have been several reports in the literature regarding the modeling aspects of solid transport in dryers. If the model is developed for model-based control, it must be simple and yet represent dynamics of the system accurately. This paper addresses solid motion modeling and the effects of different variables involved in solid transport phenomena.
A controlled field pilot has been developed in Bozeman, Montana, USA, to study near surface CO2 transport and detection technologies. A slotted horizontal well divided into six zones was installed in the shallow subsurface. The scale and CO2 release rates were chosen to be relevant to developing monitoring strategies for geological carbon storage. The field site was characterized before injection, and CO2 transport and concentrations in saturated soil and the vadose zone were modeled. Controlled releases of CO2 from the horizontal well were performed in the summers of 2007 and 2008, and collaborators from six national labs, three universities, and the U.S. Geological Survey investigated movement of CO2 through the soil, water, plants, and air with a wide range of near surface detection techniques. An overview of these results will be presented.
Experiences in hazardous materials transportation show that purely strategic or planning approaches have considerable shortcomings and that real-time management must be addressed. The commercialization of advanced location and communications technology provides the basis for real-time guidance. Considering the possibilities this new technology offers, a real-time routing model is proposed. It is based on the premises that a human dispatcher must assess the impacts of sudden events on safety and transportation costs and evaluate safe and cost-effective routing alternatives. Due to high uncertainty and time constraints in this real-time environment, risks and transportation costs are expressed as preferences on an ordinal scale. The model has been integrated into a decision support system and assessed in an experimental setting. This ordinal preference model turned out to be superior to a utility approach due to its ...
A new numerical technique called the convolution-based particle tracking (CBPT) method is developed to simulate resident or flux-averaged solute concentrations in groundwater models. The method is valid for steady-state flow and linear transport processes such as sorption with a linear sorption isotherm and first-order decay. The CBPT method uses particle tracking to take advantage of the ability of particle-based approaches to maintain sharp fronts for advection-dominated transport problems common in groundwater modeling and because of the flexibility of the random walk method to simulate a wide range of possible forms of the dispersion tensor. Furthermore, the algorithm for carrying out the convolution and superposition calculation from particle tracking results is very efficient. We sho...
This paper presents results from a research case study that examined the distribution of travel time of origin-destination (OD) pairs on a transportation network under incident conditions. Using a transportation simulation dynamic traffic assignment (DTA) model, incident on a transportation network is executed under normal conditions, incident conditions without traveler information availability, and incident conditions assuming that users had perfect knowledge of the incident conditions and could select paths to avoid the incident location. The results suggest that incidents have a different impact on different OD pairs. The results confirm that an effective traveler information system has the potential to ease the impacts of incident conditions network wide. Yet it is also important to n...
Managing service quality is vital to retain customer satisfaction and augment revenues for any business organization. Often it is difficult to assess service quality due to lack of quantifiable measures and limited data. In this paper, we present a hybrid approach based on SERVQUAL and fuzzy TOPSIS for evaluating service quality of urban transportation systems. The proposed approach consists of three steps. The first step involves development of a SERVQUAL based questionnaire to collect data for measuring transportation service quality. The participants provide linguistic assessments to rate the service quality criteria and the alternatives. In step 2, the linguistic ratings are combined through fuzzy TOPSIS to generate an overall performance score for each alternative. The alternative wit...
The effect of TP (triosephosphates:glyceraldehyde-3 phosphate, GAP, +dihydroxyacetone phosphate, DHAP) on respiration, phosphorylation and matrix ATP/ADP ratios of isolated oat mesophyll mitochondria...Full Text Available
Meteorological and air-quality data, as well as surface tracer concentration values, were collected during 1990 to assess the impact of Navajo Generating Station (NGS) emissions on Grand Canyon National Park (GCNP) air quality. These data have been used in the present investigation to determine between direct and indirect transport routes taken by the NGS plume to produce measured high-tracer concentration events at GCNP. Results show that complex-terrain features affect local wind-flow patterns during winter in the Grand Canyon area. Local channelling, decoupled canyon winds, and slope and valley flows dominate in the region when synoptic systems are weak. Direct NGS plume transport to GCNP occurs with northeasterly plume-height winds, while indirect transport to the park is caused by wind direction shifts associated with passing synoptic systems. Calculated polluted airmass positions along the modeled streak lines match ...
Plastics debris in the marine environment, including resin pellets, fragments and microscopic plastic fragments, contain organic contaminants, including polychlorinated biphenyls (PCBs), polycyclic...Full Text Available
Strain F, a recently isolated ruminal bacterium, grew rapidly with glutamate or glutamine as an energy source in the presence but not the absence of Na. Monensin, a Na+/H+ antiporter, completely inhibited...Full Text Available
The Anglo-Danish programme of research on materials for advanced vehicular transport and other storage batteries is about to enter its fifth year. Here, the results of the work to date on solid electrolytes, electrode materials and cell design are reviewed and discussed as a systematic programme of cell testing gets underway.
High temperature thermochemistry of thoria-urania fuel for Advanced Heavy Water Reactor was investigated. Oxygen potential development within the matrix and distribution behaviors of the fission products (fps) in different phases were worked out with the help of thermodynamic and transport properties of the fps as well as fission generated oxygen and the detailed balance of the elements. Some of the necessary data for different properties were generated in this laboratory while others were taken from literatures. Noting the behavior of poor transports of gases and volatile species in the thoria rich fuel (thoria-3 mol% urania), the evaluation shows that the fuel will generally bear higher oxygen potential right from early stage of burnup, and Mo will play vital role to buffer the potential through the formation of its oxygen rich chemical states. The problems related to the poor transport and larger retention of fission ...
An overall hypothesis for benzene-induced leukemia is proposed. Key components of the hypothesis include a) activation of benzene in the liver to phenolic metabolites; b) transport of these metabolites...Full Text Available
The electronic band structure, transport properties, and lattice dynamics in AuX_2 (X = Al, Ga and In) under high pressure have been extensively studied with full potential linearized augmented plane wave and pseudopotential plane wave methods. The theoretical results for the electronic band structure and Fermi surface reveal pressure-induced electronic topological transitions (ETTs) in AuGa_2 and AuIn_2, while they are absent in AuAl_2, in excellent agreement with the experimental observations. Moreover, calculations of the transport properties at different pressures reveal subtle changes in the band structure close to the Fermi surface of the three intermetallic compounds. It is clear that the anomalies in transport properties are due to ETTs. Interestingly, a pressure-induced soft transverse acoustic (TA) phonon mode is identified only in AuGa_2. The TA phonon instability at the Brillouin zone boundary L point might be ...
The ratio of particle velocity to translation speed exceeds 1 for 98% of .... The westward movement of the meandering jet and eddy system transports nutrient- rich ...... J. Hydrometeor., 4, 1044-1066. Gedney, N., P. M. Cox, H. Douville, ...
The RADionuclide Transport, Removal, And Dose (RAD-TRAD) code is designed for U.S. Nuclear Regulatory Commission (USNRC) use to calculate the radiological consequences to the off-site population and to control room operators following a design-basis accident at light water reactor (LWR) power plants. This code utilizes updated reactor accident source terms published in draft NUREG-1465. The code will track the transport of radionuclides as they are released from the reactor pressure vessel, travel through the primary containment and other buildings, and are released to the environment. As the radioactive material is transported through the primary containment and other buildings, credit for several removal mechanisms may be taken, including sprays, suppression pools, overlying pools, filters, and natural deposition. Simple models are available for these different removal mechanisms that use, as input, information about the ...
The RADionuclide Transport, Removal, And Dose (RADTRAD) code is designed for US Nuclear Regulatory Commission (USNRC) use to calculate the radiological consequences to the offsite population and to control room operators following a design-basis accident at Light Water Reactor (LWR) power plants. This code utilizes updated reactor accident source terms published in draft NUREG-1465, ``Accident Source Terms for Light-Water Nuclear Power Plants.`` The code will track the transport of radionuclides as they are released from the reactor pressure vessel, travel through the primary containment and other buildings, and are released to the environment. As the radioactive material is transported through the primary containment and other buildings, credit for several removal mechanisms may be taken including sprays, suppression pools, overlying pools, filters, and natural deposition. Simple models are available for these different ...
BackgroundThe pregnane X receptor (PXR; NR1I2), a member of the nuclear receptor superfamily, regulates the expression of metabolic enzymes and transporters involved...Full Text Available
The Nuclear Regulatory Commission (NRC), working with the National Institute of Standards and Technology (NIST), Pacific Northwest National Laboratory (PNNL), and the National Transportation Safety Board (NTSB), performed analyses to predict the response of various spent fuel transportation cask designs when exposed to a fire similar to that which occurred in the Howard Street railroad tunnel in downtown Baltimore, Maryland on July 18, 2001. The thermal performance of three different spent fuel cask designs (HOLTEC HI-STAR 100, TransNuclear TN-68, and NAC-LWT) was evaluated with the ANSYSR and COBRA-SFS analysis codes, utilizing boundary conditions for the tunnel fire obtained using NIST's Fire Dynamics Simulator (FDS) code. NRC Staff evaluated the potential for a release of radioactive material from each of the three transportation casks analyzed for the Baltimore tunnel fire scenario. The results of these analyses are ...
SummaryThe life span of C. elegans can be increased via reduced function of the mitochondria; however, the extent to which mitochondrial alteration in a single,...Full Text Available
Cultural monitoring was used to study the incidence and sources of salmonellae in a 4160 bird broiler flock during the growing period, transport and processing in a commercial plant. No salmonellae...Full Text Available
Photosynthetic (Ps) electron transport pathways often contain multiple electron carriers with overlapping functions. Here we focus on two c-type cytochromes (cyt) in facultative phototrophic...Full Text Available
The erosion phenomena of coastal regions in Italy and in the world is remarkable from the environmental point of view. Are showed activities of mechanical defense and numerical models to solve complex problem.
It has been predicted that geometrically similar animals would swim at the same speed with stroke frequency scaling with mass−1/3. In the present study, morphological and behavioural...Full Text Available
The staff of the Spent Fuel Project Office at the U.S. Nuclear Regulatory Commission undertook the investigation and thermal analysis of the Baltimore tunnel fire event. This event occurred in the Howard Street tunnel, in Baltimore, Maryland, on July 18, 2001. The staff was tasked with assessing the consequences of this event on the transportation of spent nuclear fuel. This paper describes the staff's coordination with the following government and laboratory organizations: the National Transportation Safety Board (NTSB), to determine the details of the train derailment and fire; the National Institute of Standards and Technology (NIST), to quantify the thermal conditions within the tunnel; the Center for Nuclear Waste Regulatory Analysis (CNWRA), to validate the NIST evaluations, and the Pacific Northwest National Laboratory (PNNL), to assist in the thermal analysis. The results of the staff's review and analysis efforts are ...
Accumulation of certain nonmetabolizable sugar-phosphates (including α-methyl glucoside-6-phosphate) in Escherichia coli is growth inhibitory and elicits the glucose-phosphate...Full Text Available
Apolipoprotein (apo) A-IV is a polymorphic, intestinally derived apolipoprotein that is genetically linked to and similar in structure to apoA-I, the major apolipoprotein in high density lipoproteins...Full Text Available
This paper discusses the new quality assurance regulations of the Nuclear Regulatory Commission (NRC) for packaging and transportation of radioactive materials. These regulations became effective on October 18, 1977. Background information concerning these regulations and packaging and transportation history is included. The quality assurance program is described with indications of how it is composed of general (administrative) provisions which must meet the 18 quality assurance criteria and be approved by the NRC; specific provisions which appear in the DOT and NRC regulations and in the individual package design approval; and other specific procedures which are not required by regulations but which are necessary for the proper control of quality. The quality assurance program is to be developed using a graded approach for the application of pertinent criteria and optimizing the required degree of safety and control efforts involved in ...
Eukaryotic cells can massively transport their own cytoplasmic contents into a lytic compartment, the vacuole/lysosome, for recycling through a conserved system called autophagy. The key process in...Full Text Available
Technologies for materials, processes, and manufacturing that will provide safe, .... advanced energy conversion techniques, and pulsed inductive and ... duration antimatter storage and transportation, and methods for utilizing ...... EVA systems can be found in the EVA Technology Roadmap of the EVA Project Plan. ...
Combining in situ Rutherford backscattering and electrical transport measurements on low-temperature hydrogen-implanted amorphous Pd/sub 80/Si/sub 20/ films, we have studied the correlation between the hydrogen content and the resistivity.
Sucrose and mannitol are major photosynthetic products and translocates in celery. Assimilate partitioning and transport were studied by pulse-labeling leaves with /sup 14/CO/sub 2/ followed by different length chases in ambient air. After a 2 h chase in the light there was more /sup 14/C in sucrose than mannitol in source leaves and their petioles. In contrast after a 2 h dark chase leaves contained more /sup 14/C in mannitol than sucrose but petioles had more /sup 14/C in sucrose than mannitol. After a 15 h chase (6 h light; 9 h dark) labeled sucrose was higher in source petiole vascular bundles than in adjacent parenchyma tissue but label in glucose and fructose was higher in the parenchyma tissue. After the 15 h chase most of the /sup 14/C remaining in developing sink leaves and their petioles was in mannitol. Although in the light mannitol:sucrose ratios are the same in leaf and petiole tissues, in the dark sucrose is initially the major translocate with ...
... the provisions of NASA Handbook (NHB) 6000.1, Requirements for Packaging, Handling, and Transportation, and/or MIL-STD-2073-1 and MIL-STD-2073-2, ...
The Aer protein in Escherichia coli is a membrane-bound, FAD-containing aerotaxis and energy sensor that putatively monitors the redox state of the electron transport system. Binding...Full Text Available
May 1, 2011 ... Onboard Systems Record Unique Videos of Space Missions ... Corporation, An artist's rendering of LCROSS launching toward the Moon .... Station (ISS) as part of the Commercial Orbital Transportation Services program. ...
D-galactose, a monosaccharide rapidly phosphorylated within liver cells, is irreversibly removed from the portal circulation. We have studied the kinetic relations between the hepatic cell entry process...Full Text Available
In this study we use the multiple indicator dilution technique to outline the kinetic mechanisms underlying the uptake of rubidium, a cation which, in the steady state, is concentrated by hepatic parenchymal...Full Text Available
This report discusses the following topics on superconductivity: nonlinearities in hard superconductors such as surface impedance of a type II superconductimg half space and harmonic generation and intermodulation due to alternating transport currents; and nonlinearities in superconducting weak links such as harmonic generation by a long Josephson Junction in a superconducting slab.
at 4:30 P.M. November 30, 2006 - NTSB Sends Investigators to Metro Accident in Alexandria, Virginia November 27, 2006 - (SB-06-67) John Clark Assumes New Scientific Post at...
The polarity of biological mediums controls a host of physiological processes such as digestion, signaling, transportation, metabolism, and excretion. With the recent widespread use of near-infrared...Full Text Available
Klebsiella oxytoca can use nitrate and nitrite as sole nitrogen sources. The enzymes required for nitrate and nitrite assimilation are encoded by the nasFEDCBA operon....Full Text Available
considers a wide range of pathways to advance the nation's current capabilities. The present ... opment of new energy sources, aging infrastruc- ture and ... and manufacturing TA strategic roadmap as brief- ..... pellant storage and transport. ...
The mechanism of cytokinesis has been difficult to define because of the short duration and the temporal-spatial dynamics involved in the formation, activation, force production, and disappearance of...Full Text Available
Endosomal sorting complexes required for transport (ESCRTs) are heteromeric protein complexes required for multivesicular body (MVB) morphogenesis. ESCRTs I, II, III and III-associated are ubiquitous...Full Text Available
Oct 18, 2009... jumps mostly from C-130 and C-141 Air Force transports and Army UH-1H Huey helicopters with the "All American," 82nd Airborne Division. ...
In the presence of electrochemical energy, several branched-chain neutral and acidic amino acids were found to accumulate in membrane vesicles of Bacillus stearothermophilus. The membrane vesicles contained...Full Text Available
1 to the operator of a waste collective system by an agreement or contract. The conditions for the ...Fees of the waste collective system are subject to the supervision of the authority responsible for market surveillance. ...The operator of waste collection system collects wastes from producers and holder and transports these to a collection
Serial studies of iron transport in patients on maintenance dialysis showed normal or raised values in almost all subjects and a transient increase soon after the start of dialysis in three. These...Full Text Available
Simulations with a regional chemical transport model show that anthropogenic emissions of volatile organic compounds and nitrogen oxides (NOx = NO + NO2) lead to a dramatic diurnal...Full Text Available
Background and AimsXylem vessels containing gases (embolized) must be refilled with water if they are to resume transport of water through the plant, so refilling is of great importance...Full Text Available
A detailed molecular characterization of nuclear mRNA export will require an in vitro system, allowing a biochemical reconstitution of transport. To this end, an mRNA export assay has...Full Text Available
BackgroundMethamphetamine (METH), an addictive psycho-stimulant drug with euphoric effect is known to cause neurotoxicity due to oxidative stress, dopamine accumulation and glial...Full Text Available
Over 200 mutations in the retina specific member of the ATP-binding cassette transporter super-family (ABCA4) have been associated with a diverse group of human retinal diseases....Full Text Available
In 1983, the first modern urban transit bus powered by an alternative transportation fuel took to the roads in the USA. A little more than a decade later, about 2.5% of all USA buses are powered by alternative transportation fuels and about 20% of the new bus orders for delivery by 1998 will be powered by alternative fuels, mostly by natural gas. There are over 2,200 natural gas buses in operation or on order, plus about 600 additional buses powered by other alternative fuels. When these orders are completed, alternative fuel buses will constitute over 4.4% of the urban bus fleet in the USA. The widespread use of natural gas buses in the USA provides an important transition pathway for hydrogen vehicles because of the similarities between distribution, refueling and onboard energy storage technologies for the two fuels. Projects demonstrating advanced hybrid-electric buses powered by natural gas or hydrogen and projects demonstrating hydrogen ...
BACKGROUND: Although the importance of lymphatic function is well recognized, the lack of real-time imaging modalities limits our understanding of its role in many diseases. In a phase...Full Text Available
The major neuropathological correlate of cerebral palsy in premature infants is periventricular leukomalacia (PVL), a disorder of the immature cerebral white matter. Cerebral ischemia leading...Full Text Available
This book contains papers relating to the 1990 Future Transportation Technology Conference and Exposition. Included are the following papers; Examination of rich mixtures operation of a dual fuel engine, A hybrid natural gas vehicles, Performance analysis of a spark ignited engine with ETBE as a blending agent.
The publication presents the authentic texts of the: (1) Ordinance on road transport of hazardous materials (GGVS) with the ADR, as of 1993, skeleton ordinance, annexes A and B, reasons underlying the 4th ordinance amending the GGVS, directives for implementation, RS 002, instructions for accident management, RS-006, design approval standards for packaging materials and IBC-R002. (2) Ordinance on exemptions under the GGVS (GGAV). (3) Guiding principles for the training of vehicle drivers. (4) Catalogue of monetary fines under the GGVS, BKatV. (5) Draft version of catalogue of on-the-spot cautionary fines. (6) List of materials. (7) Technical rules TR IBC 003, non-electrical equipment, TRS 003, TRS 004, TRS 005, TRS 006. (HP).
PurposeTo investigate the effects of laser photocoagulation (LP)-induced ocular hypertension (OHT) on the survival and retrograde axonal transport of retinal ganglion cells (RGC),...Full Text Available
Cultural monitoring was used to determine the incidence and sources of salmonellae in a 4160-bird broiler flock raised on litter in 32 pens. Twenty-five of the pens remained apparently free of salmonellae...Full Text Available
Field campaigns were conducted in 1981 and 1982/83 on the Dutch coast near Egmond. Measurements were made of surface elevations, water velocities and sediment concentrations in 3 to 8 surf zone locations and 2 to 5 offshore locations simultaneously. A des...
This study assesses the feasibility of removing the FFTF reactor vessel from its current location in the reactor cavity inside the Containment vessel to a transporter for relocation to a burial pit in the 200 Area.
Sandia was presented with an opportunity in 1993 to design containers for the long term storage and transport of fissile material. This program was undertaken at the direction of the US Department of Energy and in cooperation with Lawrence Livermore National Laboratory and Los Alamos National Laboratory which were tasked with developing the internal fixturing for the contents. The hardware is being supplied by Allied Signal Federal Manufacturing and Technologies, and the packaging will occur at Mason and Hangar Corporation`s Pantex Plant. The unique challenge was to design a container that could be sealed with the fissile material contents; and, anytime during the next 50 years, the container could be transported with only the need for the pre-shipment leak test. This required not only a rigorous design capable of meeting the long term storage and transportation requirements, but also resulted in development of a ...
A comparison of chlorophyll-a fluorescence in brown algae (Macrocystis integrifolia, Fucus vesiculosis), green algae (Scenedesmus obliquus, Ulva sp.)...Full Text Available
... ions. MATERIALS AND METHODS Cell Culture Culture of NT2/D1 cells was carried out as described previously (18, 19). NT2 cells were plated at a density of 2. ... ...
Based on in vitro rat and human hepatocyte uptake studies showing inhibition of warfarin uptake in the presence of the non-specific organic anion transporting polypeptide (OATP)...Full Text Available
The effects of events which occur prior to slaughter, such as loading, transport, and holding at an abattoir, on the prevalence of Campylobacter species, including Campylobacter...Full Text Available
SpoIIIE is an FtsK-related protein that transports the forespore chromosome across the Bacillus subtilis sporulation septum. We use membrane photobleaching and protoplast assays to...Full Text Available
The plant-parasitic nematode Heterodera schachtii stimulates plant root cells to form syncytial feeding structures which synthesize all nutrients required for successful nematode development....Full Text Available
BackgroundDiurnal fluctuation of bile acid (BA) concentrations in the enterohepatic system of mammals has been known for a long time. Recently, BAs have been recognized as signaling...Full Text Available
This report describes accomplishment of simulations of Pyrochemical Process Operation by using virtual engineering models. The pyrochemical process using molten salt electrorefining would introduce new technologies for new fuels of particle oxide, particle nitride and metallic fuels. This system is a batch treatment system of reprocessing and re-fabrication, which transports products of solid form from a process to next process. As a results, this system needs automated transport system for process operations by robotics. In this study, a simulation code system has been prepared, which provides virtual engineering environment to evaluate the pyrochemical process operation of a batch treatment system using handling robots. And the simulation study has been conducted to evaluate the required system functions, which are the function of handling robots, the interactions between robot and process equipment, and the time schedule of process, in the ...
Details of ion transporting abnormalities in cystic fibrosis airway epithelium are now known. The central hypothesis, that excessive drying of the airway surfaces is a primary event that leads to all...Full Text Available
ATP-binding cassette A3 (ABCA3) is a lipid transport protein required for synthesis and storage of pulmonary surfactant in type II cells in the alveoli. Abca3 was conditionally deleted...Full Text Available
Pesticide chemicals are an important component of modern agriculture. Through their use, plants and animals are exposed to pesticides directly and indirectly from transport through soil, water, and...Full Text Available
Phosphorus is an essential mineral that maintains cellular energy and mineralizes the skeleton. Because complex actions of ion transporters and regulatory hormones regulate serum phosphorus concentrations,...Full Text Available
The development of modern techniques for the cooling and the manipulation of atoms in recent years, and the possibility to create Bose-Einstein condensates and degenerate Fermi gases and to load them into regular optical lattices or disordered optical potentials, has evoked new interest for the disorder-induced localization of ultra-cold atoms. This work studies the transport properties of matter waves in disordered optical potentials, which are also known as speckle potentials. The effect of correlated disorder on localization is first studied numerically in the framework of the Anderson model. The relevant transport parameters in the configuration average over many different realizations of the speckle potential are then determined analytically, using self-consistent diagrammatic perturbation techniques. This allows to make predictions for a possible experimental observation of coherent transport phenomena for cold atoms ...
Feb 15, 2008 ... hydrological properties (e.g., hydrometeor budgets, cloud ice/water, transports ... cloud fraction, mass and particle size. In combination, these .... anomaly in the LS is not simply due isentropic movement of water vapor relative ...
Cytokinins are distributed through the vascular system and trigger responses of target cells via receptor-mediated signal transduction. Perception and transduction of the signal can occur at the plasma...Full Text Available
3-["1"2"3I]Iodo-L-#alpha#-methyl tyrosine (["1"2"3I]IMT) scintigraphy of extracranial malignant tumors has been described, but little is known about the transport systems involved in ["1"2"3I]IMT uptake into extracranial tumor cells. Here, the precise kinetics of ["1"2"3I]IMT transport into human Ewing's sarcoma cells (VH-64) was determined. The apparent Michaelis constant was of high affinity value (K_m=41.7#+-#3.9 #mu#M) and maximum transport velocity amounted to V_m_a_x=20.7#+-#0.6 nmol#centre dot#mg protein"-"1#centre dot#10 min"-"1. Inhibition experiments revealed the predominance of ["1"2"3I]IMT uptake via sodium-independent system L.
The treatment of brain disorders is one of the greatest challenges in drug delivery because of a variety of main barriers in effective drug transport and maintaining therapeutic concentrations in the...Full Text Available
DYF-13, originally identified in C. elegans within a collection of dye-filling chemosensory mutants, is one of several proteins that have been classified as putatively involved...Full Text Available
A bedload trap in the riverbed provided direct quantitative measurement of debris-transport rate in the East Fork River, Wyoming, a basin of 466 km2 drainage area. Traction load moves only...Full Text Available
Recent studies suggest that calcium influx via L-type calcium channels is necessary for psychostimulant-induced behavioral sensitization. In addition, chronic amphetamine upregulates subtype...Full Text Available
Indole-3-acetyl-myo-inositol occurs in both the kernel and vegetative shoot of germinating Zea mays seedlings. The effect of a gravitational stimulus on the transport...Full Text Available
Background and aims: Serotonin (5-hydroxtryptamine, 5-HT) is an important factor in gut function, playing key roles in intestinal peristalsis and secretion, and in sensory...Full Text Available
The Federal Highway Administration (FHWA) has put a high priority on the use of existing dynamic message signs (DMS) to provide travel time estimates to the public. The Oregon Department of Transportation (ODOT) has three DMS in the Portland metropolitan ...
Antisense radiopharmaceuticals could be used to image gene expression in the brain in vivo, should these polar molecules be made transportable through the blood–brain barrier....Full Text Available
The search for alternative fuels and new fuel resources is a top priority for Turkey, as is the case in the majority of countries throughout the world. The fuel policies pursued by governmental or civil authorities are of key importance in the success of alternative fuel use, especially for widespread and efficient use. Following the 1973 petroleum crisis, many users in Turkey, especially in transportation sector, searched for alternative fuels and forms of transportation. Gasoline engines were replaced with diesel engines between the mid-1970s and mid-1980s. In addition, natural gas was introduced to the Turkish market for heating in the early 1990s. Liquid petroleum gas was put into use in the mid-1990s, and bio-diesel was introduced into the market for transportation in 2003. However, after long periods of indifference governmental action, guidance and fuel policies were so weak that they did not make sense. ...
Albumin is a multifunctional transport protein that binds a wide variety of endogenous substances and drugs. Insulins with affinity for albumin were engineered by acylation of the epsilon-amino group...Full Text Available
Acquired resistance to the action of insulin to stimulate glucose transport in skeletal muscle is associated with obesity and promotes the development of type 2 diabetes. In skeletal muscle,...Full Text Available
The endoplasmic reticulum (ER) is an essential cellular compartment responsible for Ca2+ sequestration, signaling, protein translation, folding as well as transport. Several acute...Full Text Available
The report contains an overall frame for transformation of knowledge and experience from risk analysis to emergency education. An accident model has been developed to describe the emergency situation. A key concept of this model is uncontrolled flow of energy (UFOE), essential elements are the state, location and movement of the energy (and mass). A UFOE can be considered as the driving force of an accident, e.g., an explosion, a fire, a release of heavy gases. As long as the energy is confined, i.e. the location and movement of the energy are under control, the situation is safe, but loss of confinement will create a hazardous situation that may develop into an accident. A domain model has been developed for representing accident and emergency scenarios occurring in society. The domain model uses three main categories: status, context and objectives. A domain is a group of activities with allied goals and elements and ten specific domains have been investigated: process plant, ...
Biological membranes are lamellar structures composed of two leaflets capable of supporting different mechanical stresses. Stress differences between leaflets were generated during micromechanical experiments...Full Text Available
BackgroundSLC19A3 (solute carrier family 19, member 3) is a thiamin transporter with 12 transmembrane domains. Homozygous or compound heterozygous mutations in SLC19A3 cause...Full Text Available
In the cyanobacterium Anabaena sp. strain PCC 7120, open reading frames (ORFs) alr3026, alr3027, and all3028 encode a tripartite ATP-independent...Full Text Available
...Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION QUALIFICATION AND CERTIFICATION OF LOCOMOTIVE ENGINEERS Component Elements of the Certification Process § 240.109 General criteria for eligibility based on...
...Acquisition Regulations System 3 2010-10-01...Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF...assumption of risk for transportation by conveyance on...Missiles, and Space Launch Vehicles,...
An ion chromatograph has been modified to automatically sample ten liquid water streams from the secondary side of three pressurized water reactors, Calvert Cliffs, Unit One, Rancho Seco and McGuire, Unit 1. Sampling and measurement is semicontinuous with a cycle time of approximately five hours for 10 locations with sensitivities in the range of 0.1 to 0.5 ppb. The efficiency of the condensate polishing system and subsequent transport of sodium, chloride, and sulfate around the system can be readily followed. Sulfate has been shown to have unusual volatility into the steam phase from the steam generator as well as a tendency to pass through the condensate polisher.
The studies undertaken by the B.C. Hydro company at the Canada showed that the existing system of hydroelectric power plants and transport cables will not be able to satisfy the increasing energy demand on the Vancouver island after 1985, and that the best solution will be the installation of a 525 kV transfer system from the continent. THe STK participated to the development and the immersion of this new system, the first in the world comprising submarine 525 kV transport parts. This paper presents the planning, the development, the submerging and the installation of two sections of submarine cable.
On July 18, 2001, a freight train carrying hazardous (non-nuclear) materials derailed and caught fire while passing through the Howard Street railroad tunnel in downtown Baltimore, Maryland. The United States Nuclear Regulatory Commission (USNRC), one of the agencies responsible for ensuring the safe transportation of radioactive materials in the United States, undertook an investigation of the train derailment and fire to determine the possible regulatory implications of this particular event for the transportation of spent nuclear fuel by railroad. Shortly after the accident occurred, the USNRC met with the National Transportation Safety Board (NTSB, the U.S. agency responsible for determining the cause of transportation accidents), to discuss the details of the accident and the ensuing fire. Following these discussions, the USNRC assembled a team of experts from the National Institute of Standards ...
An algorithm is proposed which treats the ECH generated potential in a self-consistent way, by extending the Monte-Carlo Fokker-Planck method used by Murakami [S. Murakami et al., Proc. 17th IAEA Fusion Energy Conference, Yokohama, 1998 (International Atomic Energy Agency, Vienna, in press), paper CN-69/TH2/1]. The additional physics is expected to influence the transport of both thermal and suprathermal electrons in a helical toroidal system. (author)
An important aspect, which has to be considered in terms of municipal solid waste (MSW) management, is the stage of collection. The emissions generated from these systems can arrive to values that are of the same order of magnitude of emissions from combustion of waste in waste-to-energy plants. The present work faces the problem of transport, from intermediate station to the center of final combustion, placing attention to the emissions from scenarios that has been selected between real systems of management. This analysis can lead to highlight some important elements that can be useful to minimize the impacts.
The major details of the inspection and replacement of the bearing journals on each of the four heat transport pumps (HTPs) at Wolsung nuclear generating station in Korea are presented in this paper. Investigation following fracture of one of the journals in 1985 revealed that it was excessively hard. The journal material (ASTM A296 CA 40) is considered to be prone to stress corrosion fatigue if the hardness exceeds Rc 40. In 1986 May, during a planned outage, the HTPs were disassembled, the journals were inspected, found to be excessively hard, and all were replaced. At the same time, the pump to motor couplings were all refurbished to ensure proper alignment.
RADSOLVER is a computer program which calculates the radiation energy transport in cavity type receivers having an arbitrary number of apertures through which collimated beams of solar radiation enter. In contrast to the common assumption of gray (or semi-gray) surfaces used in the modeling of radiation transport, RADSOLVER accounts for the wavelength-dependence of emission, absorption and reflection with a band model of the radiative properties. It is intended that this report serve both as an instruction manual for the use of the RADSOLVER code and a vehicle for presenting the underlying theory. Illustrative examples along with input and output are presented.
The product of several advanced physical coal cleaning processes is a dry, ultrafine coal (DUC), in the order of 10 microns mean mass diameter. To utilize this fuel commercially, cost-effective, environmentally safe systems must be provided for the storage, transport, and handling of this finely divided form of fuel. The objective of the project described herein is the development of total logistics systems for DUC, including experimental verification of key features. The systems to be developed will provide for safe, economic, and environmentally protective storage and delivery of DUC for residential, commercial, and industrial uses. 20 figs.
Impurity effects on the photon-assisted spin-polarized transport through armchair carbon nanotubes connected with ferromagnetic leads are investigated theoretically. The impurity induces one resonant state whose position depends on the impurity strength, which can break the electron-hole symmetry. Whether the impurity suppresses or enhances the spin-coherent current depends on the nanotube length. When the microwave fields are applied on the nanotube, additional small side peaks caused by the photon-assisted tunneling are found. With increasing the impurity strength, one new current peak appears under the influence of both the microwave fields and the impurity.
This paper presents the objective, scope, and status of the US Department of Energy's Materials and Structures Program to develop a data base on mechanical properties of structural materials for out-of-core structures and components for LMFBRs. Information on the development of a reference data base on materials for the reactor system, reactor enclosure system, primary heat transport system, intermediate heat transport system, and steam generator system is included. In addition, the development of the data and analyses to account for the effects of temperature and stress, as well as water/steam, sodium, and radiation environments, is described. Plans for the development of alternative materials for future out-of-core applications are presented.
This paper presents the objective, scope, and status of the U.S. Department of Energy's Materials and Structures Program to develop a data base on mechanical properties of structural materials for out-of-core structures and components for LMFBRs. Information on the development of a reference data base on materials for the reactor system, reactor enclosure system, primary heat transport system, intermediate heat transport system, and steam generator system is included. In addition, the development of the data and analyses to account for the effects of temperature and stress, as well as water/steam, sodium, and radiation environments, is described. Plans for the development of alternative materials for future out-of-core applications are presented. (author).
The performance of a high temperature ion source coupled to a helium gas-jet transport system for an efficient mass separation of neutron-rich alkaline earth and lanthanide isotopes is reported and the results of overall efficiency measurements using different cluster materials in the gas-jet are given. A fast, microprocessor controlled tape transport system for ..gamma..-spectroscopic studies on short-lived isotopes is described. Some results on the decay of 3.8sub(-s) /sup 152/Pr are presented. (orig.).
The performance of a high temperature ion source coupled to a helium gas-jet transport system for an efficient mass separation of neutron-rich alkaline earth and lanthanide isotopes is reported and the results of overall efficiency measurements using different cluster materials in the gas-jet are given. A fast, microprocessor controlled tape transport system for ..gamma..-spectroscopic studies on short-lived isotopes is described. Some results on the decay of 3.8sub(-s) /sup 152/Pr are presented.
We study diffusion of Cosmic Rays (CRs) in turbulent magnetic fields using test particle simulations. Electromagnetic fields are produced in direct numerical MHD simulations of turbulence and used as an input for particle tracing, particle feedback on turbulence being ignored. Statistical transport coefficients from the test particle runs are compared with earlier analytical predictions. We find qualitative correspondence between them in various aspects of CR diffusion. In the incompressible case, that we consider in this paper, the dominant scattering mechanism occurs to be the non-resonant mirror interactions with the slow-mode perturbations. Perpendicular transport roughly agrees with being produced by magnetic field wandering.
The validation of the forecast model for early emergency response to nuclear accidents is evaluated by trace tests in atmosphere in Daya Bay nuclear power site. The simulation experiment of the Daya Bay nuclear power site shows that the particle spreading image and the time-integrated concentration distribution given by plume concentration prediction model can perform the variation of pathway of the pollutant transport, as well as the effects of topography on transport and diffusion of pollutants. The simulation of five trace tests in field shows that 59.1% of ratios between predicted results and observed results are within the range of 10, and 41% of ratios are within the range of 5 approximately. (authors)
We present a numerical method for computing diffusive transport on a surface derived from image data. Our underlying discretization method uses a Cartesian grid embedded boundary method for computing the volume transport in region consisting of all points a small distance from the surface. We obtain a representation of this region from image data using a front propagation computation based on level set methods for solving the Hamilton-Jacobi and eikonal equations. We demonstrate that the method is second-order accurate in space and time, and is capable of computing solutions on complex surface geometries obtained from image data of cells.
The heat transfer characteristics of a newly developed transport and storage cask for vitrified heat-producing radioactive waste from reprocessing are described. The theoretical layout of the cask was tested by measurements on a prototype cask of the scale 1:1. These measurements confirmed the theoretical thermodynamic layout data. They can be described by the function Nu=CxRa"m, with the constant C, but not the constant m, differing for a vertical and a horizontal position of the cask. The measured velocity and temperature profiles of the cask were verified with an existing code for the calculation of heat transfer from finned horizontal cylinders by natural convection. (orig.).
The uranium target of a gas jet transport system for fission products has been modified by the addition of an aluminum cover foil. The new modification allows fission fragments of low mass to enter a continuous chemistry system while heavier fragments are stopped in the aluminum. The elimination of the heavier homologues allows development of simpler and faster chemical separation procedures. In addition, since the lighter fragments are slowed down by the cover foil a smaller target chamber can be used. This leads to a reduction in system holdup time.
The uranium target of a gas jet transport system for fission products has been modified by the addition of an aluminum cover foil. The new modification allows fission fragments of low mass to enter a continuous chemistry system while heavier fragments are stopped in the aluminum. The elimination of the heavier homologues allows development of simpler and faster chemical separation procedures. In addition, since the lighter fragments are slowed down by the cover foil a smaller target chamber can be used. This leads to a reduction in system holdup time. (orig.).
This paper provides a concise summary of the current status of the research and future perspectives discussed in the Mini-Conference on Angular Momentum Transport in Laboratory and Nature. This Mini-conference, sponsored by the Topical Group on Plasma Astrophysics, was held as part of the American Physical Society's Division of Plasma Physics 2007 Annual Meeting (November 12{16, 2007). This Mini-conference covers a wide range of phenomena happening in fluids and plasmas, either in laboratory or in nature. The purpose of this paper is not to comprehensively review these phenomena, but to provide a starting point for interested readers to refer to related research in areas other than their own.
The author briefly discusses definition of terms, gives an introduction to measurement techniques and describes the characteristics of various low-frequency fields and their causes using typical examples: natural electric fields (thunderstroms), natural magnetic fields, technical electric constant fields (urban transportation, households), static magnetic fields (urban transportation, nuclear magnetic resonance imaging), technical electric alternating fields (high-voltage transmission lines, households), and magnetic alternating fields (high-voltage transmission lines). The author discusses both occupational exposure and that of the general public while underpinning his statements by numerous tables, measurement diagrams and charts. (Uhe).
The vacuum system of the XVTS (X-Ray Vacuum Transport System) for the LCLS (Linac Coherent Light Source) XTOD (X-ray Transport, Optics and Diagnostics) system has been analyzed and configured by the Lawrence Livermore National Laboratory's NTED (New Technologies Engineering Division) as requested by the SLAC/LCLS program. The system layout, detailed analyses and selection of the vacuum components for the XTOD tunnel section are presented in this preliminary design report. The vacuum system was analyzed and optimized using a coupled gas load balance model of sub-volumes of the components to be evacuated. Also included are the plans for procurement, mechanical integration, and the cost estimates.
Multi-machine experimental observations indicate resilience in the temperature profiles at low pedestal temperatures,whereas at high pedestal temperatures the profile stiffness seems to disappear.The change of the profile behavior impacts the energy confinement,basically due to a strong non-linear dependence of the energy transport on the pedestal temperature together with different critical conditions for the onset of turbulence in the ions and electrons.This possible explanation for the different observations is based on the assumption that both ion and electron energy transport is governed by turbulence which sets in at a critical temperature gradient as well as on a significant energy equipartition between electrons and ions.
Role of ballooning effect in toroidal plasmas on the transient transport problems is investigated. Due to the mode localization along the magnetic field line, a meso scale appears in a radial correlation length of fluctuating fields. This scale length introduces the interference of the gradient and flux in different radial locations. For the fluctuation which gives the gyro-Bohm-like diffusion in a stationary state, this long radial correlation of the fluctuating field causes a fast propagation of response against a rapid transient perturbation. Upper bound of transient thermal diffusivity is derived. (author)
We have developed EOS7M, a ferrofluid flow and transport module for TOUGH2. EOS7M calculates the magnetic forces on ferrofluid caused by an external magnetic field and allows simulation of flow and advective transport of ferrofluid-water mixtures through porous media. Such flow problems are strongly coupled and well suited to the TOUGH2 framework. Preliminary applications of EOS7M to some simple pressure and flow problems for which experiments were carried out in the lab show good qualitative agreement with the laboratory results.
Epoxy-resin based neutron shielding material, NS-4-FR, is used for spent fuel transport and/or storage cask. In this paper the outline of thermal aging test performed to evaluate the heating effect on this neutron shielding material, NS-4-FR, is introduced. The test is consisted of two kinds of thermal aging test, one is 'Basic Test' and the other is 'Block Heating Test'. The former is cooperatively performed by ten Japanese Electrical Power Companies, and the latter is done by GESC and NOF Corporation. (authors)
Epoxy-resin based neutron shielding material, NS-4-FR, is used for spent fuel transport and/or storage cask. In this paper the outline of thermal aging test performed to evaluate the heating effect on this neutron shielding material, NS-4-FR, is introduced. The test is consisted of two kinds of thermal aging test, one is 'Basic Test' and the other is 'Block Heating Test'. The former is cooperatively performed by ten Japanese Electrical Power Companies, and the latter is done by GESC and NOF Corporation. (authors)
The objective of this contract is to research, develop and demonstrate a novel ceramic membrane reactor system for the low-cost conversion of natural gas to synthesis gas and hydrogen for liquid transportation fuels: the ITM Syngas process. Through an eight-year, three-phase program, the technology will be developed and scaled up to obtain the technical, engineering, operating and economic data necessary for the final step to full commercialization of the Gas-to-Liquids (GTL) conversion technology. This report is a summary of activities through February 1999.
The objective of this contract is to research, develop and demonstrate a novel ceramic membrane reactor system for the low-cost conversion of natural gas to synthesis gas and hydrogen for liquid transportation fuels: the ITM Syngas process. Through an eight-year, three-phase program, the technology will be developed and scaled up to obtain the technical, engineering, operating and economic data necessary for the final step to full commercialization of the Gas-to-Liquids (GTL) conversion technology. This report is a summary of activities through September 1999.
A clear and reproducible transition to a regime with an improved particle confinement is routinely observed on the CASTOR tokamak, if the biasing electrode is inserted deep enough into the plasma (r/a?0.5) and biased up to +250 V. The steepening of the radial profiles of the plasma density and potential demonstrate the formation of a transport barrier just inside the last closed flux surface. Fast relaxations of the edge plasma parameters, with a frequency of about 10 kHz, are observed when the average radial electric field within the barrier prevails values of about 20 kV/m. A detailed analysis of the spatial-temporal behaviour of these relaxations is presented.
We have designed a new nucleobase, benzodeazaadenine (BDA) that has a stronger charge transport ability than guanine and is not destroyed during charge transport process. By incorporating this new nucleobase into DNA, we demonstrated a protocol for real DNA nano-wire that is far superior to natural DNA. We also demonstrated that the selectivity for the interaction of Mn(II) ion with guanine N7 in G runs is a HOMO-controlled process, and as a consequence, the selectivity for G-metal ion interactions obtained by 15N-NMR studies would directly reflect the HOMO distribution of G-containing sequences in B-DNA. PMID:12903077
The purpose of this project is to integrate a variety of geographic information systems capabilities and telecommunication technologies for potential use in geographic network and visualization applications. The specific technical goals of the project were to design, develop, and simulate the components of an audio/visual geographic communications system to aid future real-time monitoring, mapping and managing of transport vehicles. The system components of this feasibility study are collectively referred to as a Geographic Visualization and Communications System (GVCS). State-of-the-art techniques will be used and developed to allow both the vehicle operator and network manager to monitor the location and surrounding environment of a transport vehicle during shipment.
This study identifies the environmental conditions under which less CO{sub 2}-emitting and more expensive automobile technology might enter the North American transportation sector. For that purpose, different exogenous CO{sub 2}-reduction targets are imposed and the resulting market shares of hypothetical future automobile technologies calculated. The criteria for the selection of different types of automobiles/fuels is the minimisation of discounted, cumulative transport sector costs over the scenario time horizon. (author) 1 tab., 6 refs.
An analysis of the current state of track-laying operations in open-cut mines is given and their labor intensive nature is noted. The lag in the technological development of mechanization equipment for track laying and repair operations is noted. Results are given from developments by the Scientific Research Institute of Open-Pit Mining Operations in the field of mobile transportation technology and promising modular route design. Also examined are the problems of improving the routing bases in the industry. The absence of factories for manufacturing transportation technology and equipment is reflected most evidently in the technical and cost characteristics of coal production by an open-cut method and requires immediate solution.
In this short communication, we discuss the energy consumption trends in the Malaysian road transport sector, with a special emphasis on the energy losses due to vehicle aerodynamic drag on highways. The recent trends of energy consumption in the Malaysian road transport sector are reviewed. It is evidently shown that the aerodynamic losses represented exceed 1.2MTOE annually since 2002. A novel concept of vertical-axis wind turbine (VAWT) farms for harvesting aerodynamic energy losses on Malaysian highways is preliminarily proposed. The novel concept aims at providing a sustainable and green energy source for the lighting of the highway network in the country.
The GntR-like protein NorG has been shown to affect Staphylococcus aureus genes involved in the resistance to quinolones and ?-lactams, such as those encoding the NorB and AbcA transporters. To identify the target genes regulated by NorG, we carried out transcriptional profiling assays using S. aureus RN6390 and its isogenic norG::cat mutant. Our data showed that NorG positively affected the transcription of global regulators mgrA, arlS, and sarZ. The three putative drug efflux pump genes most positively affected by NorG were the NorB efflux pump (5.1-fold), the MmpL-like protein SACOL2566 (5.2-fold), and the BcrA-like drug transporter SACOL2525 (5.7-fold). The S. aureus predicted MmpL protein showed 53% homology with the MmpL lipid transporter of Mycobacterium tuberculosis, and the putative SACOL2525 protein showed 87% homology with the bacitracin drug transporter BcrA of Staphylococcus hominis. Two ...
This guide describes the simulator`s governing equations, constitutive functions and numerical solution algorithms of the STOMP (Subsurface Transport Over Multiple Phases) simulator, a scientific tool for analyzing multiple phase subsurface flow and transport. The STOMP simulator`s fundamental purpose is to produce numerical predictions of thermal and hydrologic flow and transport phenomena in variably saturated subsurface environments, which are contaminated with volatile or nonvolatile organic compounds. Auxiliary applications include numerical predictions of solute transport processes including radioactive chain decay processes. In writing these guides for the STOMP simulator, the authors have assumed that the reader comprehends concepts and theories associated with multiple-phase hydrology, heat transfer, thermodynamics, radioactive chain decay, and nonhysteretic relative permeability, ...
DBA/2J (DBA) mice are susceptible to audiogenic seizures (ASs) in an age-dependent manner. Anion transport as measured by radioiodide uptake was determined in thyroid gland, salivary gland, skeletal muscle, cerebral cortex, cerebellum, brainstem, and CSF from these mice at various ages. Anion transport was also determined in C57BL/6J(C57) mice, an AS-resistant strain. In thyroid, DBA mice had an enhanced ability to concentrate iodide at 21 days of age when they have maximal AS susceptibility, as compared with the same-aged C57 mice. This difference in thyroid function was less marked at 40 days of age, when DBA mice are less AS susceptible, and was absent at 110 days of age, when DBA mice are AS resistant. In brain, differences in iodide uptake were also noted between these two strains of mice at 21 days of age. DBA mice had an increased concentration of iodide in CSF, an indication that they have a defect in the transport ...
This report summarizes preliminary 2-D reactive-transport simulations on the injection, storage and transport of supercritical CO{sub 2} in dolostone formations in the Ordos Basin in China. The purpose of the simulations was to evaluate the role that basin heterogeneity, permeability, CO{sub 2} flux, and geochemical reactions between the carbonate geology and the CO{sub 2} equilibrated brines have on the evolution of porosity and permeability in the storage reservoir. The 2-D simulation of CO{sub 2} injection at 10{sup 3} ton/year corresponds to CO{sub 2} injection at a rate of 3 x 10{sup 5} ton/year in a 3-D, low permeable rock. An average permeability of 10 md was used in the simulation and reflects the upper range of permeability reported for the Ordos Basin Majiagou Group. Transport and distribution of CO{sub 2} between in the gas, aqueous, and solid phases were followed during a 10-year injection phase and a 10-year ...
Simulation and experimental results on the transport of microbes and nutrients in one-dimensional cores are presented, and the development of a three-dimensional, three-phase, multiple-component numerical model to describe the microbial transport and oil recovery in porous media is described. The change of rock's wettability and associated relative permeability values after microbial treatments were accounted for in the model for additional oil recovery. Porosity and permeability reductions due to cell clogging have been considered and the production of gas by microbial metabolism has been incorporated. Governing equations for microbial and nutrient transport are coupled with continuity and flow equations under conditions appropriate for a black oil reservoir. The computer simulator has been used to determine the effects of various transport parameters on microbial ...
Simulation and experimental results on the transport of microbes and nutrients in one-dimensional cores are presented, and the development of a three-dimensional, three-phase, multiple-component numerical model to describe the microbial transport and oil recovery in porous media is described. The change of rock`s wettability and associated relative permeability values after microbial treatments were accounted for in the model for additional oil recovery. Porosity and permeability reductions due to cell clogging have been considered and the production of gas by microbial metabolism has been incorporated. Governing equations for microbial and nutrient transport are coupled with continuity and flow equations under conditions appropriate for a black oil reservoir. The computer simulator has been used to determine the effects of various transport parameters on microbial transport ...
As part of The International Northern Sea Route Programme (INSROP), Subprogram III, Trade and Commercial Shipping, a study has been made concerning seaborne export of liquefied petroleum gas (LPG) from the Northern Russia, especially the West Siberian fields in Tyumen. The main purpose of the total project III.0703, part 2 and this study is to evaluate the economic viability of seaborne export from this area to the European region, mainly with the use of a special ice-strengthened LPG vessel, constructed and designed for such seaborne operations. This study concentrates on both seaborne LPG transportation, the demand and supply for seaborne LPG in the world and marine transportation of LPG from the West Siberian fields. Another purpose is to see which regions are potential exporters, importers and buyers of seaborne export of LPG from Tyumen. Currently large quantities of liquefied gas are flared off at the West Siberian fields due to ...
The US Department of Energy (DOE) is preparing to perform significant remediation activities of the sites for which it is responsible. To accomplish this, it is preparing a corporate global plan focused on activities over the next decade. Significant in these planned activities is the transportation of the waste arising from the remediation. The costs of this transportation are expected to be large. To support the initial assessment of the plan, a cost estimating model was developed, peer-reviewed against other available packaging and transportation cost data, and applied to a significant number of shipping campaigns of radioactive waste. This cost estimating model, known as the Ten-year Plan Transportation Cost Model (TEPTRAM), can be used to model radioactive material shipments between DOE sites or from DOE sites to non-DOE destinations. The model considers the costs for (a) recovering and processing ...
The authors have investigated insulin receptor phosphorylation in differentiated cultured BC3H-1 myocytes. As for other insulin-responsive cell systems in partially purified wheat germ agglutinin receptor preparations, insulin stimulates the phosphorylation of its own receptor (95K ..beta..-subunits) in a dose dependent manner (0-400 nM), as identified by immunoprecipitation with antiinsulin receptor antibodies and SDS-PAGE. In the same preparations they show that 12-0-tetradecanyl phorbol acetate (TPA), which in many respect ..beta..-subunits in the same dose dependent manner (0-5 ..mu..M). In addition, antiinsulin receptor antibodies (B-10) also induced phosphorylation of mimics insulin action, also induced phosphorylation of the insulin receptor and HPLC tryptic maps of the /sup 32/P-labeled ..beta..-subunit were identical to those for insulin-induced receptor phosphorylation. However, while insulin and TPA are potent stimulators of glucose transport in these ...
Three blocks of non-welded tuff, one nominally one cubic foot (trial block) and the other two, nominally one cubic metre (1 m{sup 3}), were excavated from the Busted Butte Test Facility on the Nevada Test Site and transported to the Atomic Energy of Canada Limited Whiteshell Laboratories in Pinawa, Manitoba. The trial block and one of the 1-m{sup 3} blocks were used for unsaturated flow experiments. The remaining 1-m{sup 3} block is being used for saturated flow experiments and will be reported on separately. After a vertical flow of synthetic transport solution was set up under unsaturated conditions, a suite of conservative and chemically reactive radionuclide tracers was injected at volumetric flow rates of 20 mL/hr in the trial block, and 10 mL/hr in the 1-m{sup 3} block. The duration of the migration experiment in the trial block was 87 days, while the migration experiment in the 1-m{sup 3} block was continuing after 600 days. Results ...
According to the present concept, the low and intermediate level wastes generated during the Cernavoda NPP operation will be disposed in a near surface repository. The Saligny site, placed in the NPP protected area, has been proposed for their disposal. Geologically, the main components of this site are the quaternary loess, the Precambrian and Pre-quaternary clays, the Eocene and Barremian limestone. Hydrologically, the site can be divided into a vadose zone down to 45-50 m and three distinct aquifers, two of them in the limestone beds and the third in the lenses of sand and limestone existing in the pre-quaternary clay layer. A large research program for site characterization was initiated in 1996. At present, the site characteristics requested for safety analysis have been experimentally measured on soil samples or calculated by different computer programs. Hundreds of experimental values of the density, porosity, hydraulic conductivity, soil-water retention, moisture content or ...
The quantum $N$-body problem is studied in the context of nonrelativistic quantum mechanics with a one-dimensional deformed Heisenberg algebra of the form $[\\hat x,\\hat p]=i(1+\\beta \\hat p^2)$, leading to the existence of a minimal observable length $\\sqrt\\beta$. For a generic pairwise interaction potential, analytical formulas are obtained that allow to estimate the ground-state energy of the $N$-body system by finding the ground-state energy of a corresponding two-body problem. It is first shown that, in the harmonic oscillator case, the $\\beta$-dependent term grows faster with $N$ than the $\\beta$-independent one. Then, it is argued that such a behavior should be observed also with generic potentials and for $D$-dimensional systems. In consequence, quantum $N$-body bound states might be interesting places to look at nontrivial manifestations of a minimal length since, the more particles are present, the more the system deviates from ...
The structure of Bi/sub 1.8/Ce/sub 0.2/(MoO/sub 4/)/sub 3/ has been refined with powder neutron diffraction data by the Rietveld method. The structure can be derived by severely distorting the scheelite structure (AMO/sub 4/) and is perhaps better written A/sub (2/3)/phi/sub (1/3)/MO/sub 4/, where phi = cation vacancy. Of the two bismuth atom sites, cerium preferentially occupies the more symmetric of the two (Bi(2) in the structure) with some cerium found in the scheelite subcell vacancies also. This site preference is understood by examining the symmetries of the two Bi sites. Crystal data: monoclinic, space group P2/sub 1//c, Z = 4, a = 7.697(2), b = 11.535(3), c = 11.944(3), ..beta.. = 115.19.
Neutron elastic and inelastic scattering cross sections of _2_3_8U and _2_3_2Th have been measured at the University of Lowell for states below 1.8 MeV. A time-of-flight (TOF) spectrometer was used. The disc-shaped scatterer was oriented to optimize energy resolutions for 200-to-500-keV neutrons. Neutrons were obtained via the _7Li(p,n)_7Be reaction. Targets were prepared by in-situ evaporation of Li onto a Ta backing. During the evaporation, the target thickness was monitored using a 5-m-flight-path TOF spectrometer; a typical target had a neutron thickness from 8 to 10 keV for Esub(p) = 2.25.MeV. Spectra were analyzed using the unfolding code TINA; standard peak shapes were obtained from codes LAGUE and LAPA. Results obtained will be presented.
The authors studied the flow of carbon ({sup 14}C) from CO{sub 2} through sucrose to oligofructans in wheat (Triticum aestivum L.) leaves that had been induced by excision to accumulate fructan. Leaves were either labeled for 30 min and then chased in ambient air for 2 h or labeled continuously for 2 h. Fructans were chromatographed on BioGel P2 column. During continuous labeling, the specific activity was highest in sucrose and decreased for fructans with DP 3 to 5, and each increased linearly with time for 2 h. During the chase period, sucrose specific activity increased for 60 min and then declined while oligofructans gained in specific activity through the 2 h period. After 30 min of labeling, the specific activity of fructose moiety of sucrose was equal to glucose but, in oligofructans, those of the individual fructose units were not. The results may provide insight into the fructosyl donor-acceptor pool relations in wheat leaves.
A study was carried out to identify optimal laminate/oil combinations for low pressure oil filled and high pressure pipe-type cables, and to establish taping criteria under factory conditions. Laminates from two sources were evaluated in conjunction with Sun XX high viscosity mineral oil and Cosden 015SH polybutene oil for high pressure type cables, and Dussek TC-2288N mineral oil, Shell P2 dedecylbenzene and Chevron DF-100 alkylbenzene for low pressure oil-filled cables. Swelling tests, infrared analysis, dissipation and dielectric measurements, impulse tests and a taping trial were performed. It was found that there is no appreciable difference in performance of both laminates when tested on model cables in a variety of oils. Both types exhibited superior aging characteristics vis-a-vis cellulose paper when tested with a variety of oils and at temperatures up to 105{degree}C. For pipe type cable, high viscosity polybutene is the most suitable ...
Excessive use of poultry litter (PL) on agricultural land is known to cause eutrophication of surface waters. Consequently, both poultry producers and PL users have to meet strict state and federal guidelines on litter storage and land application. This study examined the environmental benefits of adding lime, alum, ferrous sulfate, fly ash (FA), fluidized bed ash (FBA) and soil fix (SF) to PL for immobilizing excess phosphorus (P) while providing sufficient nutrients for proper growth of soybean [Glycine max (L.)] and corn [Zea mays (L.)] on a rotation. Amending PL with lime, alum, SF, FA and FBA significantly (p>0.05) increased corn and soybean yield. In contrast control plots that received a 10-10-10 (N-P2O5-K2) fertilizer showed lower yield and corn quality. Increased yield was ob...
Excitation functions (EFs) for the reaction "1"4"1Pr(#alpha#, n)"1"4"4Pm and "1"4"1Pr(#alpha#, 2n)"1"4"3Pm have been measured using "1"4"1Pr as a target up to 50 MeV #alpha#-particle energy. Stacked foil activation technique and #gamma#-ray spectroscopy using 100 cm"3 Ge (Li) detector, has been used. Excitation functions are also calculated theoretically using Blann's geometry dependent hybrid (GDH) model code ALICE-91, with and without inclusion of pre-equilibrium particle emission. It has been observed that high-energy tails of the EFs are dominated by pre-equilibrium reaction mechanism. With the accepted set of input parameter, initial exciton number n_0=4 (2p + 2n + 0h), a good qualitative agreement is found. However, quantitative agreement for this magic nucleus"1"4"1Pr is also good when theoretical calculations are normalized by a multiple factor of 0.5. (author)
The glasses with the composition of 37.5Li2O?(25?x)Fe2O3?xNb2O5?37.5P2O5 (mol%) (x=5,10,15) are prepared, and it is found that the addition of Nb2O5 is effective for the glass formation in the lithium iron phosphate system. The glass?ceramics consisting of Nasicon-type Li3Fe2(PO4)3 crystals with an orthorhombic structure are developed through conventional crystallization in an electric furnace, showing electrical conductivities of 3?10?6?Scm?1 at room temperature and the activation energies of 0.48?eV (x=5) and 0.51?eV (x=10) for Li+ ion conduction in the temperature range of 30?200??C. A continuous wave Nd:YAG laser (wavelength: 1064?nm) with powers of 0.14?0.30?W and a scanning speed of 10??m/s is irradiated onto the surface of the glasses, and the formation of Li3Fe2(PO4)3 crystals is c...
The first-order relativistic correction to the kinetic energy of an electron, the mass-velocity term, is not bounded from below. It can, therefore, not be used within a variational framework. To overcome this deficiency we developed a method to include the entire relativistic kinetic energy #sq root#(p"2c"2+m_0"2c"4)-m_0c"2 in a spline-augmented plane-wave band calculation. The first results for silver are quite promising, especially for d and p states: The analysis of the energies of the core states as well as of the valence band structure suggests that the energies of d bands are reproduced within 1 mRy. However, the combination of the relativistic kinetic energy with the Darwin term leads to energies which are too low for s-like valence states by 10 mRy. Therefore, the s and d valence band complex is spread out and the Fermi level is lowered by the same amount as the s states. We expect to overcome these deficiencies in future investigations ...
Electron-excitation cross sections are reported for the 3s "2S#->#3p "2P(h,k) resonance transition in Mg"+ at energies from threshold (4.43 eV) to approximately 9 times threshold (40.0 eV). The electron-energy-loss merged-beams technique used in these measurements is described in detail. In addition, the method of separating contributions of the elastically scattered (Coulomb) and the inelastically scattered electrons in the present Mg"+ case and previously reported Zn"+ results [Phys. Rev. Lett. 67, 30 (1991)] is described. Comparisons in the experimental energy range are made for Mg"+ with the two five-state close-coupling theoretical calculations carried out herein, and with other published close-coupling, distorted-wave, and semiempirical calculations. The present Mg"+ cross sections and Zn"+ cross sections from earlier measurements are tabulated.
In this study, the excitation functions for the reactions "2"0"3Tl(p, n)"2"0"3Pb, "2"0"5Tl(p, 3n)"2"0"3Pb, "2"0"3Tl(p, 2n)"2"0"2Pb, "2"0"5Tl(p, 4n)"2"0"2Pb, "2"0"3Tl(p, 3n)"2"0"1Pb, "2"0"5Tl(p, 5n)"2"0"1Pb, "2"0"3Tl(p, 4n)"2"0"0Pb and "2"0"5Tl(p, 6n)"2"0"0Pb have been calculated using pre-equilibrium and equilibrium reactions mechanisms. Calculated results based on hybrid model, geometry-dependent hybrid model and cascade-exciton model have been compared with the experimental data. (author)
This paper studies the way in which confinement leads to chiral symmetry breaking (CSB) through a gap equation. We argue that entropic effects cut off infrared singularities in the standard confining effective propagator $1/p^4$, which should be replaced by $1/(p^2+m^2)^2$ for a finite mass $m\\sim K_F/M(0)$ [$M(0)$ is the zero-momentum value of the running quark mass]. Extension of an old calculation of the author yields a specific estimate for $m$. This cutoff propagator shows semi-quantitatively two critical properties of confinement: 1) a negative contribution to the confining potential coming from entropic forces; 2) an infrared cutoff required by gauge invariance and CSB itself. Entropic effects lead to a proliferation of pion branches and a $\\bar{q}q$ condensate, and contribute a negative term $\\sim -K_F/M(0)$ to the effective pion Hamiltonian allowing for a massless pion in the presence of positive kinetic energy and string energy. ...
The National Ignition Facility (NIF) will be a U.S. Department of Energy (DOE) national center for inertial confinement fusion (ICF) and other research into the physics of high temperatures and high densities, and a vital element of the DOE`s nuclear weapons Stockpile Stewardship and Management Program. It will be used by scientists from a numerous different institutions and disciplines to support research advancements in national security, energy, basic science, and economic development. Multiple powerful laser beams will `ignite` small fusion targets, helping liberate more energy than is required to initiate the fusion reactions. This paper discusses the Design for Environment process for NIF, some of the subsequent activities resulting from the initial study, and a few of the lessons learned from this process. Subsequent activities include the development of a Pollution Prevention and Waste Minimization Plan (P2/WMin) for the facility, which ...
The design of the KSTAR (Korea Superconducting Tokamak Advanced Research) tokamak (R{sub 0} = 1.8 m, a= 0.5 m, {kappa} = 2, {delta} = 1.8 B{sub T} = 3.5 T, I{sub p} 2 MA, {tau}{sub pulse} = 300 s) is being undertaken to do long-pulse. high {beta}, advanced tokamak operating-mode fusion physics experiments. The ion cyclotron (IC) system will deliver 6 MW of rf power to the plasma in the 25 - 60 MHz frequency range, using a single four-strap antenna mounted in a midplane port. It will be used for ion heating, fast-wave current drive (FWCD), and mode conversion current drive (MCCD). The phasing between current straps in the antenna will be adjustable quickly during operation to provide the capability of changing the current-drive efficiency. The IC system will be capable of 300 s operation with 12 MW (upgrade) of rf power to the plasma. (author)
The 2- and 8-azido trimer 5'-triphosphate photoprobes of 2-5A have been enzymatically synthesized from [#gamma#-"3"2P]2-azidoATP and [#alpha#-"3"2P]8-azidoAPT by 2-5A synthetase from rabbit reticulocyte lysates. Identification and structural determination of the 2- and 8-azido adenylate trimer 5'-triphosphates were accomplished by enzymatic hydrolyses with T2 RNase, snake venom phosphodiesterase, and bacterial alkaline phosphatase. Hydrolysis products were identified by HPLC and PEI-cellulose TLC analyses. The 8-azido photoprobe of 2-5A displaces p_3A_4["3"2P]pCp from RNase L with affinity equivalent to p_3A_3. The 8-azido photoprobe also activates RNase L to hydrolyze poly(U)["3"2P]pCp 50% at 7 /times/ 10/sup /minus/9/ M in core-cellulose assays. The 2- and 8-azido photoprobes and authentic p_3A_3 activate RNase L to cleave 28S and 18S rRNA to specific cleavage products at 10/sup /minus/9/ M in rRNA cleavage assays. The nucleotide binding ...
Research highlights: {yields} The use of resonant photoemission in its 'core-hole clock' expression for the study of the dynamical charge transfer across hybrid organic-inorganic interfaces and for the intermolecular charge transfer in the bulk of organic thin films is reviewed. {yields} The electronic coupling to the substrate and the efficiency of charge transport across hybrid interfaces is different for individual electronic subsystems of the molecular adsorbate. {yields} The intermolecular charge transfer in the bulk of discotic liquid crystals occurs on the order of a few femtoseconds and is faster than expected from the macroscopic charge transport characteristics of the material. -- Abstract: The focus of this brief review is the use of resonant photoemission in its 'core-hole clock' expression for the study of two important problems relevant for the field of organic electronics: the dynamical charge ...
A series of upper tropospheric radon concentration measurements made over the eastern Pacific and west coast of the United States during the summers of 1983 and 1984 has revealed the occurrence of unexpectedly high (>16 pCi/SCM) radon concentrations for 9 of the 61 measurements (and 6 of the 13 flights). A frequency distribution plot of the set of 61 observations shows a distinct bimodal distribution, with approximately 2/5 of the observations falling close to 1 pCi/SCM, and 3/5 falling in a high concentration mode centered at about 11 pCi/SCM. Trajectory and synoptic analyses for two of the flights on which such high radon concentrations were observed indicate that this radon-rich air originated in the Asian boundary layer, ascended in cumulus updrafts, and was carried eastward in the fast moving air on the anti-cyclonic side of the upper tropospheric jet. Transit times were of the order of 3 days; however, in one instance, transport from China to a point a few ...
Computational transport models are described with applications in three problem areas related to unsaturated zone moisture movement beneath Area G. These studies may be used to support the ongoing maintenance of the site Performance Assessment. The three areas include: a 1-D transient analysis with average tuff hydraulic properties in the near surface region with computed results compared to field data; the influence on near surface transient moisture percolation due to realistic distributions in hydraulic properties derived statistically from the observed variance in the field data; and the west to east moisture flow in a 2-D steady geometry approximation of the Pajarito Plateau. Results indicate that a simple transient model for transport of moisture volume fraction fits field data well compared to a moisture pulse observed in the active disposal unit, pit 37. Using realistic infiltration boundary conditions for summer showers and for spring ...
In situ assembly states of rat adipocyte glucose transport protein in plasma membrane (PM) and in microsomal pool (MM) were assessed by measuring target size (TS) of D glucose-sensitive, cytochalasin B binding activity. High energy radiation inactivated the binding in both PM and MM by reducing the total capacity of the binding (B/sub T/) without affecting the dissociation constant (K/sub D/). The reduction in B/sub T/ as a function of radiation dose was analyzed based on classical target theory, from which TS was calculated. TS in the PM of insulin-treated adipocytes was 58 KDa. TS in the MM of noninsulin-treated and insulin-treated adipocytes were 112 and 109 KDa, respectively. With MM, however, inactivation data showed anomalously low radiation sensitivities at low radiation doses showing a shoulder in the semilog plots, which may be due to an interaction with a radiation sensitive inhibitor. With these results, they propose the following model: Adipocyte ...
In building new pipelines, the main preoccupation of the countries along the Persian Gulf is transport safety. The shortest or the most profitable route is no longer sought, but rather the politically least dangerous route. If in itself the decrease in dependency on a single route and the multiplication of pipelines reduce vulnerability, transport costs by pipeline are always higher than maritime transport costs. Moreover, still another economic factor has to be considered, that of drilling in the seas, which today represents about 20% of production, a percentage which is likely to increase. Oil produced on continental shelves can be delivered from a platform to tankers almost as it comes out of the well. In this case, it seems to be completely irrational to transport this oil through one or several countries and then to deliver it to a tanker. And so, dependency on the Straits of Hormuz is ...
The mechanism of lead transport is presented, and especially the particular similarities or dissimilarities between lead and calcium in this process. The absorption of these metals was determined cockerels, raised on a commercial diet or on a specified diet, using in vivo ligated loop procedure. The dose administered into the loop contained 0.5 #mu#Ci "2"0"3Pb (and/or 0.1 #mu#Ci "4"7Ca), and 0.01 mM lead acetate (and/or mM CaCl_2) in 0.5 ml 0.15 M NaCl,pH 6.5. It was shown that lead is rapidly taken up by the mucosal tissue, and slowly transferred into the body, whereas less calcium is retained by the tissue and the transfer of calcium is many times as effective as that for lead. They appear to respond in a similar manner to a low calcium intake and vitamin D treatment. Increasing luminal stable lead concentration significantly reduced the percentage of radiolead significantly reduced the percentage of radiolead absorbed, but did not affect the absorption of ...
In front of the risks linked with the increase of the greenhouse gas emissions in the atmosphere, the decision makers must take into consideration first, the scientific advice of climatic change experts, and second, the considerable inertia of the climatic system. Thus, any action implemented so far will have an impact all along the 21. century and later whatever the future human activities. The aim of this memento is to sensibilize the decision makers about the possible consequences of their choice in terms of volume of greenhouse gases and of medium- and long-term evolution: 1 - stakes, role of local decision-makers (greenhouse effect and climatic change, France's international commitment, stakes, liabilities of local decision makers, decentralization laws, local plans of fight against greenhouse effect, public information and dialogue); 2 - urbanism and transports (urban displacements, alternatives to individual cars, collective ...
There was a total bus strike in the Danish town of Esbjerg during the spring of 1995. It lasted for a very long period of time and was extremely disruptive. After this the number of bus passengers fell dramatically. As a result, a group of researchers in this field, employed at Aalborg University initiated an investigation of how former bus passengers solved their personal transport problems without the help of a bus service. Telephone interviews were carried out and 1485 persons agreed to take part in the investigation. The data collected in this way are presented in the paper and give information on the number of people who owned cars, how often members of a family availed themselves of bus transport, age groups, the alternative means of transport used generally or for conveyance to the place of work or school, amount of extra, or less, travel time, travel expenses, and other irritations experienced in connection with the ...
Attention-deficit hyperactivity disorder (ADHD) has been shown to be familial and heritable, in previous studies. As with most psychiatric disorders, examination of pedigrees has not revealed a consistent Mendelian mode of transmission. The response of ADHD patients to medications that inhibit the dopamine transporter, including methylphenidate, amphetamine, pemoline, and bupropion, led us to consider the dopamine transporter as a primary candidate gene for ADHD. To avoid effects of population stratification and to avoid the problem of classification of relatives with other psychiatric disorders as affected or unaffected, we used the haplotype-based haplotype relative risk (HHRR) method to test for association between a VNTR polymorphism at the dopamine transporter locus (DAT1) and DSM-III-R-diagnosed ADHD (N = 49) and undifferentiated attention-deficit disorder (UADD) (N = 8) in trios composed of father, mother, and ...
This is the third quarterly progress report for Year 3 of the ACTS Project. It includes a review of progress made in: (1) Flow Loop construction and development and (2) research tasks during the period of time between Jan. 1, 2002 and Mar. 31, 2002. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 3: Addition of a Cuttings Injection/Separation System), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 9b): ''Study of Foam Flow Behavior Under EPET Conditions'', (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (e) Research on three ...
US Department of Energy (DOE) Order 5820.2A (DOE, 1988) requires performance assessments on all new and existing low-level radioactive waste (LLW) disposal sites. An integral part of performance assessment is estimating the fluxes of radioactive gases such as radon-220 and radon-222. Data needs pointed out by mathematical models drive site characterization. They provide a logical means of performing the required flux estimations. Thorium-230 waste, consisting largely of thorium hydroxide and thorium oxides, has been approved for disposal in shallow trenches and pits at the LLW Radioactive Waste Management Site in Area 5 of the Nevada Test Site. A sophisticated gas transport model, CASCADR8 (Lindstrom et al., 1992b), was used to simulate the transport and fate of radon-222 from its source of origin, nine feet below a closure cap of native soil, through the dry alluvial earth, to its point of release into the atmosphere. CASCADR8 is an M-chain ...
A new foilless diode with a non-magnetically immersed cathode was recently designed and built for the Sandia Recirculating Linear Accelerator (RLA). Because there is also no radial component of electric field at the cathode, the electron beam starts almost parallel and is matched to a solenoidal transport system with minimum increase in divergence and radius. The electrode emission surface is specified by an area covered with felt which undergoes explosive electron emission at low electrical field stresses (60 kV/cm). The 1.7 MV, 4.8-kA produced beam is transported 1.5 meters to the injection region of the racetrack via a system of solenoids and focusing coils. The maximum transverse velocity component at injection point (1.5 m downstream from the cathode surface) is #beta# perpendicular = 0.03 and the radius r = 2.8 cm which give a quite small beam emittance #epsilon# = 0.08 rad-cm. Three- dimensional numerical simulations suggest that ...