p1 b1 b2: Topics by WorldWideScience.org

Degradation of ?-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26

We consider an admissible fibration $\\pi:X\\to\\mathbb{P}^1$ over a curve over a number field, of which the generic fiber $X_\\eta$ is geometrically rationally connected. We suppose that there exists a generalized Hilbertian subset $\\textsf{Hil}$ of $\\mathbb{P}^1$, such that the Brauer-Manin obstruction is the only obstruction to the Hasse principle (resp. to the weak approximation) for $X_\\theta(\\theta\\in \\textsf{Hil}).$ We prove that the Brauer-Manin obstruction is the only obstruction to the Hasse principle (resp. to the strong approximation) for zero-cycles of degree 1 on $X$ in the following cases: $(B_1)$ the index of the generic fibre $X_\\eta$ is equal to 1; $(B_2)$ all fibers are geometrically integral. Then, we obtain some similar results for certain fibrations over $\\mathbb{P}^n$. As a consequence, we ...

2010-01-01

3

Selecting Folded Proteins from a Library of Secondary Structural Elements

b2;-Hexachlorocyclohexane (b2;-HCH) is the most recalcitrant among the b1;-, b2;-, γ-, and δ-isomers of HCH and causes serious environmental pollution problems....Full Text Available

2005-04-01

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Noncooperativity of the ?? Dimer in the Reaction of Hemoglobin with Oxygen

A protein evolution strategy is described by which double-stranded DNA fragments encoding defined E. coli protein secondary structural elements (b1;-helices, b2;-strands...Full Text Available

2008-01-09

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Theoretical study of the phonon properties of SrS

The theory that the b1;b2; dimer is the functional unit of cooperativity in hemoglobin has been tested by determination of the oxygen equilibrium curve of stable deoxy dimers, obtained by...Full Text Available

1972-01-01

6

Active Site of ?-Chymotrypsin Activation by Association-Desolvation

Using an ab initio pseudopotential method within a generalized gradient approximation of the density functional theory, the structural, electronic, and phonon properties of SrS in the B1 (NaCl) and B2 (CsCl) structures have been studied. The calculated lattice constants, static bulk modulus, and first-order pressure derivative of the bulk modulus are reported for both the B1 and B2 structures and compared with previous experimental and theoretical calculations. Electronic band structures and densities of states have been derived for SrS. Subsequently, a linear-response approach to the density functional theory is used to derive the phonon frequencies and densities of states.

2009-05-25

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On the Origins of the Weak Folding Cooperativity of a Designed ??? Ultrafast Protein FSD-1

High reactivity toward b1;-chymotrypsin is observed for derivatives of b2;-arylpropionic acids of varied structure—L-b1;-acylamido compounds, D-cyclized compounds, and, now,...Full Text Available

1970-06-01

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The YTH Domain Is a Novel RNA Binding Domain*

FSD-1, a designed small ultrafast folder with a b2;b2;b1; fold, has been actively studied in the last few years as a model system for studying protein folding mechanisms and for testing...Full Text Available

2010-11-01

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Purinergic receptors are involved in tooth-pulp evoked nocifensive behavior and brainstem neuronal activity

The YTH (YT521-B homology) domain was identified by sequence comparison and is found in 174 different proteins expressed in eukaryotes. It is characterized by 14 invariant residues within an b1;-helix/b2;-sheet...Full Text Available

2010-05-07

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Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation

BackgroundTo evaluate whether P2X receptors are involved in responses to noxious pulp stimulation, the P2X₃and P2X_2/3receptor agonist b1;,b2;-methyleneATP...Full Text Available

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The pressure- and temperature dependence of the electrical resistivity of some amorphous Fe-B alloys

BackgroundEstrogen receptors alpha (ERb1;) and beta (ERb2;) are transcription factors (TFs) that mediate estrogen signaling and define the hormone-responsive phenotype...Full Text Available

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Susceptible gene single nucleotide polymorphism and hemorrhage risk in patients with brain arteriovenous malformation

We report measurements of the electrical resistivity of the amorphous alloys Fe"4"0Ni"4"0P"1"4B"6 (Metglas 2826), Fe"3"2Ni"3"6Cr"1"4Pr"1"2B"6 (Metglas 2826A) Fe"8"0B"2"0 (Metgals 2605) and Fe"7"5B"2"5 as a function of pressure and temperature. The pressure is varied between 0 and 12 GPa, the temperature between 1.2 and 380 K. At low temperatures the pressure dependence yields additional information on the scattering mechanism. (orig.).

13

British Library Electronic Table of Contents (United Kingdom)

The relationship between single nucleotide polymorphism (SNP) of interleukin-17 (IL-17A), transforming growth factor @b (TGF-@b), as well as its receptor (TGFR-@b2) and susceptibility to intracerebral hemorrhage in patients with brain arteriovenous malformation (BAVM) was investigated in the present study. A total of 53 patients with BAVM and 120 healthy controls were recruited, all of whom were Han Chinese from South China. There were no statistically significant differences in the IL-17A-197 guanine/adenine (G/A) or TGF-@b1-509 cytosine/thymine (C/T) genotypes or gene frequencies between BAVM patients and controls (p>0.05), but the gene frequency of the TGFR-@b2-875 A/G genotype in patients with BAVM was significantly higher (p<0.05). Furthermore, the frequencies of the G allele of IL-17...

2011-01-01

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Molybdenum complexes of biochemical interest. New coordination complexes of oxomolybdenum(V) with the tridentate ONO donor Schiff bases derived from salicylaldehydes and ethanolamine

EPR, optical, infrared and Raman studies of VO"2"+ ions in polyvinylalcohol films

New oxomolybdenum(V) complexes MoOClL (where LH_2 = Schiff base) derived from ethanolamine and salicylaldehyde, 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, 5-nitrosalicylaldehyde, 3-ethoxysalicylaldehyde and 2-hydroxy-1-naphthaldehyde have been synthesized and characterised by elemental analyses, conductance, molecular weight, i.r. and electronic spectra and magnetic measurements. The Schiff bases behave as dibasic tridentate ONO donor ligands. The complexes are non-electrolytes and dimers. The complexes exhibit subnormal magnetic moments and are involved in antiferromagnetic exchange with S = 0 ground state. The complexes exhibit electronic spectral bands at ca. 13000 and ca. 17000 cm"-"1 due to the transitions dsub(xy)->dsub(xz,yz) ("2B_2->"2E) and dsub(xy)->dsub(x2-y2) ("2B_2->"2B_1), respectively. The #nu#(Mo=O) frequency of the complexes is ...

1985-01-01

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Assessment of epidermal growth factor receptor (EGFR, ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb, GW572016) in an expanded panel of human normal and tumour cell lines

Electron paramagnetic resonance (EPR), optical, infrared and Raman spectral studies have been carried out on vanadyl ions doped in polyvinylalcohol (PVA) films. The spin-Hamiltonian parameters (g and A) and the molecular orbital coefficients (#beta#_2"*"2 and k) have been evaluated. The values of spin-Hamiltonian parameters confirm that the vanadyl ions are present in PVA films as VO"2"+ molecular ions in an octahedral site with a tetragonal compression (C_4_v). The temperature variation EPR studies reveal that the variation of number of spins with temperature is in accordance with Boltzmann law. It is interesting to observe that the variation of susceptibility with temperature obeys Curie-Weiss law. The FT-IR and FT-Raman spectrum exhibits few bands, which are attributed to O-H, C-H, C-C and C-O groups of stretching and bending vibrations. The optical absorption spectrum exhibits two bands, which are assigned to ...

2007-01-15

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British Library Electronic Table of Contents (United Kingdom)

Abstract. Objective: Lapatinib (Tykerb, GW572016), a potent inhibitor of the catalytic activities of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) (ErbB2), inhibits population growth of selected EGFR and HER2 overexpressing cell lines. Previous studies with a small number of cell lines suggest a correlation between overexpression of EGFR and/or HER2 and sensitivity to growth inhibition by lapatinib; however, the precise determinants of lapatinib selectivity for tumour and/or other cells remain unclear. Materials and methods: To clarify the determinants of its selectivity in cultured cells, lapatinib-induced cell population growth inhibition and relative EGFR and HER2 protein expression were quantified in 61 different human tumour cell lines fro...

2007-01-01

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Phase stability, electronic and elastic properties of ScN

Acid-base behavior of the ground and excited states of platinum(II) complexes of quinoxaline-2,3-dithiolate

The structural stability, electronic and elastic properties of ScN under high pressure were investigated by using full-potential linearized augmented plane-wave (FP-LAPW) method. Our calculations indicate that there exists a pressure-induced structural phase transformation from the ambient rock-salt (B1) phase to CsCl-type (B2) phase above 335 GPa. The origin of moderate high bulk modulus, mechanical and high melting point was analyzed by electronic properties. The variations of elastic constants (C_i_j) with volume and pressure have been investigated. Moreover, the volume dependencies of Debye temperature, the longitudinal and transverse elastic wave velocities have been presented.

2010-06-01

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Dose conversion factor for radon concentration in indoor environments using a new equation for the F-f_p correlation

The acid-base behavior of the ground and excited states of Pt(qdt){sub 2}{sup 2{minus}} and Pt(phen)(qdt), where qdt=quinoxaline-2,3-dithiolate and phen = 1,10-phenanthroline, has been studied. The pH-dependent changes in the charge-transfer absorption and emission spectra for both complexes are attributed to protonation of the quinoxalinedithiolate ligand at the imine nitrogen. For Pt(qdt){sub 2}{sup 2{minus}}, single protonation leads to a large red shift (2582 cm{sup {minus}1}) of the low-energy charge-transfer-to-dithiolate absorption band and the emergence of a new red-shifted emission feature at 728 nm. In solutions of pH below 6, a second protonation takes place at the other qdt ligand, yielding Pt-(Hqdt){sub 2}. This neutral complex has been isolated and characterized by {sup 1}H NMR spectroscopy and elemental analyses. The ground-state basicity constants of the two protonation steps have been determined from spectrophotometric titrations to be pK{sub ...

1995-06-21

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The metabolism of the isomeric decalones

Since 1994 the radon studies group at the Institut de Techniques Energetiques (INTE) of the Universitat Politecnica de Catalunya in Barcelona, Spain, has carried out a campaign of continuous measurements of the equilibrium factor (F) and the unattached fraction (f_p) of radon decay products at four sites which are representative of different environmental characteristics on the Mediterranean littoral of Catalonia, Spain. It has been established that these parameters vary widely, F(0.03--0.87) and f_p (0--0.72), from one site to another and with time, according to the characteristics on the site and climate. In spite of this variation, the F and f_p parameters are log-normally or normally distributed. The measurements of F and f_p show that f_p is negatively correlated to F by a log-power equation, Ln(1/f_p)=1.90[Ln(1/F)]"-"0"."6"8, which can be used in all the F range, instead of the commonly used power equation f_p=aF"b suggested by Stranden ...

2000-01-01

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Genetic organization of Bungarus multicinctus protease inhibitor-like proteins.

1. The metabolism of (�b1;)-cis-1-, (�b1;)-trans-1-, (�b1;)-cis-2- and (�b1;)-trans-2-decalone in the rabbit...Full Text Available

1966-08-01

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Acute Asthma Responsiveness and B2 Adrenergic Receptors Polymorphisms

The structural organization of the genes encoding Bungarus multicinctus protease inhibitor-like proteins (PILPs), PILP-1, PILP-2 and PILP-3, are reported in this study. Unlike PILP-2 and PILP-3, recombinant PILP-1 exhibited inhibitory activity on trypsin. PILP genes and B chain genes shared identical organization with three exons interrupted by two introns in similar positions. On the contrary, intron 1 of these genes had a similar size, a notable variation with the size of intron 2 was observed. It was found that two regions at the second intron of B1 chain and B2 chain genes were absent in that of PILP genes. Noticeably, intronic insertion in the second intron of B chain genes appeared in the promoter region of PILP-1 gene, but not in that of PILP-2 and PILP-3 genes. Comparative analyses of PILP genes and B chain genes showed that the protein-coding regions of the exons are more diverse than introns, ...

2008-03-27

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[New cardiotonic agents].

Acute Asthma

2011-05-24

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Zonal differences in DNA synthesis activity and cytochrome P450 gene expression in livers of male F344 rats treated with five nongenotoxic carcinogens

The possibilities for therapy in the field of severe cardiac insufficiency have been extended in recent years by the introduction of novel agents endowed with a positive inotropic action. These substances may be arranged in two large classes: sympathomimetic agents and "non sympathomimetic--non digitalis-like" inotropic agents. The stimulant action of noradrenaline, adrenaline and isoproterenol on beta-adrenergic myocardial receptors has been clearly demonstrated but the usefulness of these medicines is limited by their positive chronotropic and arrhythmogenic actions. Dopamine and dobutamine have proved to be very useful in the treatment of patients in intensive care units. However, the exclusively intravenous route of administration limits their importance to the medium or long term. Several compounds, which are active by the oral route, have been the subject of therapeutic trials for the short or medium term. The problems posed by their use result, in the first place, from an ...

1985-12-01

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Preoperative staging of rectal carcinoma with combined sonography and pelvic computed tomography

Both increased cell proliferation and {open_quotes}altered{close_quotes}CYP gene expression are prominent phenomena associated with liver tumor promotion by nongenotoxic carcinogen treatment. BRDU-labeled parenchymal nuclei were observed primarily in the periportal area of groups of rats, independent of nongenotoxic carcinogen treatment. Treatment with each of the 5 nongenotoxic carcinogens resulted in profound alterations in CPY gene expression at both the transcriptional and translational levels. Expression of CYP1A1, 1A1/2, 3A1, 2B1/2, and 4A immunoproteins demonstrated nongenotoxic carcinogen-specific patterns in both magnitude and zonal distribution. In agreement with the CYP immunoprotein data, treatment with each of the five nongenotoxic carcinogens resulted in a unique composition of mRNAs of CYP2B1, 2B2, 2C6, 2C11, 3A1, 3A2, and 4A1, which were variably ...

1995-12-31

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Influence of metallurgical factors on corrosion and electrochemical behavior of structural materials

The accurate staging of rectal carcinoma is very important for treatment planning. The histological data obtained from surgical specimens of 22 patients with rectal carcinoma were compared with pre-and postoperative endorectal US findings and with preoperative CT results. According to an adapted version of Astler and Coller classification, the different degrees of tumor spread into the rectal wall were represented as follows: stage A: 1 patient; stage B1: 5 patients; stage B2: 6 patients; stage C1: 1 patient; stage C2: 8 patients and stage D: 1 patient. Preoperative staging, based on the overall results of CT and US, was in agreement with histology in 19 of 22 cases. Individual analysis of US and CT results, in comparison with histological data, showed US staging accuracy to be 77.3% (17/22 patients). US accuracy in demonstrating tumor spread into the rectal wall (stages A, ...

1991-01-01

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CYP1B1 mutations in Spanish patients with primary congenital glaucoma: phenotypic and functional variability

An analysis of the passive films formed on amorphous alloys of the system Fe-10% Cr-5% Mo-P-metalloid and Fe-10% Cr-5% Mo-B-Si revealed that they are more markedly enriched with chromium in silicon-free alloys. In silicon-containing amorphous alloys the passive films were highly enriched with silicon, which occurred in these films in the form of a corrosion product close to SiO_2. As shown by the investigations of a study of the anodic behavior of Fe_4_0Ni_4_0P_1_4B_6 and Fe_4_0Ni_3_8Mo_4B_1_8, phosphorus facilitates the passivation of amorphous alloys by reducing the solution current in the active state and enriching the surface layers of the metal in the form of a black prepassivation film which also contains nickel and iron. The behavior of Fe-Ni amorphous alloys containing only boron as metalloid additive differs little from that of crystalline alloys of similar composition but without the boron. ...

1986-01-01

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Practical application of a simplified vitamin B_1_2 radioassay

PurposeTo analyze the contributions of cytochrome P4501B1 (CYP1B1) mutations to primary congenital glaucoma (PCG) in Spanish patients.MethodsWe...Full Text Available

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biotechnological studies on the effect of gamma rays on peanut

... blood serum patients radioimmunoassay sampling tracer techniques isotope

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Internalized insulin-receptor complexes are unidirectionally translocated to chloroquine-sensitive degradative sites. Dependence on metabolic energy

local peanut cultivars Giza 4 and Giza 5 were exposed to different doses ( 50,100,150,200,250 and 300 Gy)to Co "6"0 gamma ray source . all irradiated materials were cultivated to give the M_1 and M_2 generation , then high yielding mutants were selected from the M_2 generation and cultivated separately to give the M_3 generation. some yield component traits were measured for the three generations (M_1,M_2 and M_3) and M_3 families.variations observed in these traits were attributed to genetic factors. the M_3 selected mutants were artificially infected by aspergillus flavus L spores (aflatoxins-B1 and B2 groups-producer strain). aflatoxin concentrations were estimated and the analysis showed that aflatoxin concentrations in seeds of the M_3 selected mutants from cultivar Giza 4 were higher than those in seeds of the M3 mutants selected from cultivar Giza 5. however, the concentration of aflatoxin ...

2007-01-01

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Role of B2 Adrenergic Receptors in Labor Pain

Insulin receptors on the surface of isolated rat adipocytes were photoaffinity labeled at 12 degrees C with the iodinated photoreactive insulin analogue, 125I-B2 (2-nitro-4-azidophenylacetyl)-des-PheB1-insulin, and the pathways in the intracellular processing of the labeled receptors were studied at 37 degrees C. During 37 degrees C incubations, the labeled 440-kDa insulin receptors were continuously internalized (as assessed by trypsin inaccessibility) and degraded such that up to 50% of the initially labeled receptors were lost by 120 min. Metabolic poisons (0.125-0.75 mM 2,4-dinitrophenol (DNP) and 1-10 mM NaF), which led to dose-dependent depletion of adipocyte ATP pools, inhibited receptor loss, and caused up to 3-fold increase in intracellular receptor accumulation. This effect was due to inhibition of intracellular receptor degradation, and there was no apparent effect of the metabolic poisons on ...

1988-04-25

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Cellular Sources of Transforming Growth Factor-? Isoforms in Early and Chronic Radiation Enteropathy

Pain; Pain Threshold; Labour Pain

2010-10-01

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Development of a business-to-business critical success factors (B2B CSFs) framework for Chinese SMEs

The three mammalian transforming growth factor (TGF)-b2; isoforms (TGF-b2;1, TGF-b2;2, and TGF-b2;3) differ in their putative roles in radiation-induced fibrosis in intestine...Full Text Available

1998-11-01

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British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to critically explore business-to-business critical success factors (B2B CSFs) for small and medium-sized enterprises (SMEs) operating in the Chinese B2B marketplace, evaluate the findings, and use the generated CSFs to propose a framework to assist in the marketing management of B2B in China. The proposed framework provides a guideline for academics and practitioners and highlights the significant role of each factor in developing and sustaining effective B2B electronic commerce (B2B e-commerce) practice for SMEs. Design/methodology/approach - The proposed framework is constructed by combining the empirical findings and B2B literature. The quantitative (online survey) was targeted at, proprietors, ...

2011-01-01

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The Caenorhabditis elegans Elongator Complex Regulates Neuronal ?-tubulin Acetylation

PYRROLO[1,2-b][1,2,5]BENZOTHIADIAZEPINES (PBTDs) induce apoptosis in K562 cells

Although acetylated b1;-tubulin is known to be a marker of stable microtubules in neurons, precise factors that regulate b1;-tubulin acetylation are, to date, largely unknown. Therefore,...Full Text Available

2010-01-01

35

Distribution of ?-Galactosidase in Cucurbita pepo 1

BackgroundThe objective of this study was to gain insight into the molecular mechanism of induced cell death (apoptosis) by PYRROLO [1,2-b][1,2,5]BENZOTHIADIAZEPINES...Full Text Available

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Inactivation of aflatoxin B1 by using the synergistic effect of hydrogen peroxide and gamma radiation

The distribution of b1;-galactosidase (b1;-d-galactoside galactohydrolase [EC 3.2.1.22]) in Cucurbita pepo has been determined in an attempt to assess its involvement...Full Text Available

1978-11-01

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Transforming growth factor-?1 induces intestinal myofibroblast differentiation and modulates their migration

Inactivation of aflatoxin B1 was studied by using gamma radiation and hydrogen peroxide. A 100-krad dose of gamma radiation was sufficient to inactivate 50 micrograms of aflatoxin B1 in the presence of 5% hydrogen peroxide, and 400 krad was required for total degradation of 100 micrograms of aflatoxin in the same system. Degradation of aflatoxin B1 was confirmed by high-pressure liquid chromatographic and thin-layer chromatographic analysis. Ames microsomal mutagenicity test showed loss of aflatoxin activity. This method of detoxification also reduces the toxin levels effectively in artificially contaminated groundnuts.

1989-02-01

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The biosynthesis of rubber from ?-hydroxy-?-methylglutaryl-coenzyme A in Hevea brasiliensis latex

AIM: To investigate the effects of transforming growth factor b2;1 (TGF-b2;1) on the differentiation of colonic lamina propria fibroblasts (CLPF) into myofibroblasts in vitro.METHODS:...Full Text Available

2009-03-28

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Physicochemical Characterization of Berberine Chloride: A Perspective in the Development of a Solution Dosage Form for Oral Delivery

1. b2;-Hydroxy-b2;-methyl[3-¹⁴C]glutaryl-CoA is efficiently incorporated into rubber on incubation with Hevea brasiliensis latex, and the incorporation is diminished...Full Text Available

1969-09-01

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Effects of ?-Cyclodextrin on the Structure of Sphingomyelin/Cholesterol Model Membranes

The objective of the present research was to evaluate the physicochemical characteristics of berberine chloride and to assess the complexation of drug with 2-hydroxypropyl-b2;-cyclodextrin (HPb2;CD),...Full Text Available

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miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NF?B1

The interaction of b2;-cyclodextrin (b2;-CD) with mixed bilayers composed of sphingomylein and cholesterol (Chol) above and below the accepted stable complexation...Full Text Available

2010-09-08

42

Synergistic epigenetic reactivation of estrogen receptor-? (ER?) by combined green tea polyphenol and histone deacetylase inhibitor in ER?-negative breast cancer cells

The activation of nuclear factor-kappa B1 (NFκB1) in cancer cells may confer resistance to ionizing radiation (IR). To enhance the therapeutic efficiency of IR in lung cancer, we screened for...Full Text Available

2011-05-31

43

Phosphorylation of ?6-Tubulin by Protein Kinase C? Activates Motility of Human Breast Cells*

BackgroundThe status of estrogen receptor-b1; (ERb1;) is critical to the clinical prognosis and therapeutic approach in breast cancer. ERb1;-negative breast cancer...Full Text Available

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Ephrin B1 Regulates Bone Marrow Stromal Cell Differentiation and Bone Formation by Influencing TAZ Transactivation via Complex Formation with NHERF1?

Engineered overexpression of protein kinase Cb1; (PKCb1;) was previously shown to endow nonmotile MCF-10A human breast cells with aggressive motility. A traceable mutant of PKCb1;...Full Text Available

2009-06-26

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Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates

Mutations of ephrin B1 in humans result in craniofrontonasal syndrome. Because little is known of the role and mechanism of action of ephrin B1 in bone, we examined the function of osteoblast-produced...Full Text Available

2010-02-01

46

Covalent Modification of Thr302 in Cytochrome P450 2B1 by the Mechanism-Based Inactivator 4-tert-Butylphenylacetylene

Cytochrome P450 1B1 (Cyp1b1) metabolism contributes to physiological functions during embryogenesis, but also to carcinogenic activation of polycyclic aromatic hydrocarbons (PAH). We generated...Full Text Available

2008-09-15

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The Effects of ?-Helical Structure and Cyanylated Cysteine on Each Other

The mechanism of inactivation of cytochrome P450 2B1 (CYP2B1) by 4-tert-butylphenylacetylene (BPA) has been characterized previously to be caused by the covalent binding of a reactive...Full Text Available

2010-06-01

48

Fine mapping of a foot-and-mouth disease virus epitope recognized by serotype-independent monoclonal antibody 4B2.

b2;-Thiocyanatoalanine, or cyanylated cysteine, is an artificial...Full Text Available

2010-04-15

49

KoreaScience (Korea)

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2011-02-01

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The K3 Fragment of Amyloidogenic ?₂-Microglobulin Forms Ion Channels: Implication for Dialysis Related Amyloidosis

Specific Sequence Motif of 8-Cys Repeats of TGF-? Binding Proteins, LTBPs, Creates a Hydrophobic Interaction Surface for Binding of Small Latent TGF-?

b2;₂-microglobulin (b2;₂m) amyloid deposits are linked to dialysis related amyloidosis (DRA) in hemodialysis patients. The mechanism by which b2;₂m...Full Text Available

2009-10-21

51

Molecular and functional characterization of a novel chromoplast-specific lycopene ?-cyclase from Citrus and its relation to lycopene accumulation

Transforming growth factor (TGF)-b2;s are secreted in large latent complexes consisting of TGF-b2;, its N-terminal latency-associated peptide (LAP) propeptide, and latent TGF-b2;...Full Text Available

2000-08-01

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Mice With a Deletion in the Gene for CCAAT/Enhancer-Binding Protein ? are Protected Against Diet-Induced Obesity

Carotenoids are the main pigments responsible of the colouration of Citrus fruits. The b2;-cyclization of lycopene, catalysed by the lycopene b2;-cyclases (b2;-LCY),...Full Text Available

2009-04-01

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Crystal Structure of the Mycobacterium fortuitum Class A ?-Lactamase: Structural Basis for Broad Substrate Specificity

The CCAAT/enhancer-binding protein b2; (C/EBPb2;) is required for adipocyte differentiation and maturation. We have studied the role of the transcription factor, C/EBPb2;,...Full Text Available

2007-01-01

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Contribution of Gene Amplification to Evolution of Increased Antibiotic Resistance in Salmonella typhimurium

b2;-Lactamases are the main cause of bacterial resistance to penicillins and cephalosporins. Class A b2;-lactamases, the largest group of b2;-lactamases, have been found in many bacterial...Full Text Available

2006-07-01

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Evidence for the h_b(1P) meson in the decay Upsilon(3S) --> pi0 h_b(1P)

The use of b2;-lactam antibiotics has led to the evolution and global spread of a variety of resistance mechanisms, including b2;-lactamases, a group of enzymes that degrade the b2;-lactam...Full Text Available

2009-08-01

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Study of the reactions "1"0"4Ru(d,p)"1"0"5Ru and "1"0"0Mo(d,p)"1"0"1Mo

Using a sample of 122 million Upsilon(3S) events recorded with the BaBar detector at the PEP-II asymmetric-energy e+e- collider at SLAC, we search for the h_b(1P) spin-singlet partner of the P-wave chi_b(1P) states in the sequential decay Upsilon(3S) --> pi0 h_b(1P), h_b(1P) --> gamma eta_b(1S). We observe an excess of events above background in the distribution of the recoil mass against the pi0 at mass 9902 +/- 4 (stat.) +/- 1 (syst.) MeV/c^2. The width of the observed signal is consistent with experimental resolution, and its significance is 3.0 sigma, including systematic uncertainties. We obtain the value (3.7 +/- 1.1 (stat.) +/- 0.7 (syst.))x 10^{-4} for the product branching fraction BF(Upsilon(3S) --> pi0 h_b) x BF(h_b --> gamma eta_b).

2011-01-01

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Forkhead box protein P1 as a downstream target of transforming growth factor-b induces collagen synthesis and correlates with a more stable plaque phenotype

... reactions differential cross sections dwba excitation excited states mev range

1975-04-07

58

British Library Electronic Table of Contents (United Kingdom)

Objective: Atherosclerosis is an inflammatory disease, modulated by plaque stabilizing and de-stabilizing cell populations such as infiltrating monocytes and vascular smooth muscle cells (vSMCs). Transcription factors regulating proliferation and differentiation of atherosclerosis relevant cell types are of interest in this context. The forkhead box transcription factor FoxP1 modulates monocyte differentiation. We studied FoxP1 expression in atherosclerotic tissue, correlated FoxP1 expression with plaque characteristics and identified associations between FoxP1 and plaque proteins. Methods: 116 Atherosclerotic plaques from carotid endarterectomy samples were histologically classified (fibrous, fibroatheromatous, atheromatous) and subjected to semi-quantitative protein analysis. Macrophage,...

2011-01-01

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Results from the photoemission spectroscopy beamline 2B1 at Pohang Light Source

Phosphorylation of Annexin A1 by TRPM7 Kinase: A Switch Regulating the Induction of an ?-Helix

The results of photoemission spectroscopy using molybdenum and tantalum samples have been obtained from the new beamline 2B1 at Pohang Light Source. Beamline 2B1 is based on a spherical grating monochromator (SGM) which is equipped with five gratings. The photon energy range from 184 to 1100 eV was covered in this work using two gratings (Gratings 4 and 5). The photon energy resolution has been deduced from Ta Fermi-level spectra and 3d spectra of Mo.

1999-06-01

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A 12b 1kS/s 65uA 0.35um CMOS Algorithmic ADC for Sensor Interface in Ubiquitous Environments

TRPM7 is an unusual bifunctional protein consisting of an b1;-kinase...Full Text Available

2011-03-29

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KoreaScience (Korea)

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2008-03-01

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Transport and superconducting properties of RNi_2B_2C (R=Y, Lu) single crystals

Luminescence and second harmonic generation in Eu3+/Eu2+ embedded B2O3: LiNbO3 non-linear glass-ceramics

The in-plane resistivity, in-plane absolute thermopower, and upper critical field measurements are reported for single-crystal samples of YNi_2B_2C and LuNi_2B_2C superconductors. The in-plane resistivity shows metallic behavior and varies approximately linearly with temperature near room temperature (RT) but shows nearly quadratic behavior in temperature at low temperatures. The YNi_2B_2C and LuNi_2B_2C single-crystal samples exhibit large transverse magnetoresistance (#approx#6 8% at 45 kOe) in the ab plane. The absolute thermopower S(T) is negative from RT to the superconducting transition temperature T_c. Its magnitude at RT is a few times of the value for a typical good metal. S(T) is approximately linear in temperature between #approx#150 K and RT. Extrapolation to T=0 gives large intercepts (few #mu#V/K) for both ...

63

Tamsulosin oral controlled absorption system (OCAS) in the treatment of benign prostatic hypertrophy

Not Available

2011-09-01

64

Single Particle Tracking of ?7 Nicotinic AChR in Hippocampal Neurons Reveals Regulated Confinement at Glutamatergic and GABAergic Perisynaptic Sites

The efficacy of tamsulosin at the cost of a relatively benign side effect profile has been attributed to receptor selectivity directed at the b1;_1a and b1;_1d adrenergic...Full Text Available

2008-02-01

65

Serum Globotriaosylceramide Assay as a Screening Test for Fabry Disease in Patients with ESRD on Maintenance Dialysis in Korea

b1;7 neuronal nicotinic acetylcholine receptors (b1;7-nAChR) form Ca²⁺-permeable homopentameric channels modulating cortical network activity and cognitive processing....Full Text Available

66

Rosiglitazone and fenofibrate improve insulin sensitivity of pre-diabetic OLETF rats by reducing malonyl-CoA levels in the liver and skeletal muscle

Background/AimsFabry disease is an X-linked recessive and progressive disease caused by b1;-galactosidase A (b1;-GaL A) deficiency. We sought to assess the prevalence...Full Text Available

2010-12-01

67

Myocardial metabolic regulation through peroxisome proliferator-activated receptor alpha after myocardial infarction

AimsRosiglitazone and fenofibrate, specific agonists of the peroxisome proliferator activated receptors-γ (PPARγ) and -b1; (PPARb1;),...Full Text Available

2009-05-08

68

Modulation of Retinoic Acid Receptor-related Orphan Receptor ? and ? Activity by 7-Oxygenated Sterol Ligands*

Although peroxisome proliferator-activated receptor alpha (PPARb1;) is closely associated with myocardial fatty acid metabolism, the pathophysiological role of PPARb1; in myocardial infarction...Full Text Available

2003-01-01

69

Induction of Porphyrin Synthesis in Etiolated Bean Leaves by Chelators of Iron ¹²

The retinoic acid receptor-related orphan receptors b1; and γ (RORb1; (NR1F1) and RORγ (NR1F3)) are orphan nuclear receptors and perform critical roles in regulation of development,...Full Text Available

2010-02-12

70

Forkhead Box Transcription Factor FOXO3a Regulates Estrogen Receptor Alpha Expression and Is Repressed by the Her-2/neu/Phosphatidylinositol 3-Kinase/Akt Signaling Pathway

Primary leaves of 7- to 9-day-old etiolated seedlings of Phaseolus vulgaris L. var. Red Kidney infiltrated in darkness with aqueous solutions of b1;, b1;′-dipyridyl,...Full Text Available

1974-02-01

71

Estrogen metabolite ratio: Is the 2-hydroxyestrone to 16?-hydroxyestrone ratio predictive for breast cancer?

The expression status of the estrogen receptor alpha (ERb1;) and that of the epidermal growth factor receptor Her-2/neu frequently correlate inversely in breast cancers. While ERb1;-dependent...Full Text Available

2004-10-01

72

Crystallization and preliminary X-ray diffraction studies of two thermostable ?-galactosidases from glycoside hydrolase family 36

Experimental studies have shown that two main estrogen metabolites hydroxylated by CYP1A1 and CYP1B1 in the breast differentially affect breast cell proliferation and carcinogenesis. Although 16b1;-hydroxyestrone...Full Text Available

73

Characterization of a Novel Small Molecule Subtype Specific Estrogen-Related Receptor ? Antagonist in MCF-7 Breast Cancer Cells

b1;-Galactosidases from thermophilic organisms have gained interest owing to their applications in the sugar industry. The b1;-galactosidases AgaA, AgaB and AgaA A355E mutant from Geobacillus...Full Text Available

74

Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines as EGFR and ErbB-2 inhibitors

BackgroundThe orphan nuclear receptor estrogen-related receptor b1; (ERRb1;) is a member of the nuclear receptor superfamily. It was identified through a search for genes...Full Text Available

75

British Library Electronic Table of Contents (United Kingdom)

A novel class of pyrrolidinyl-acetyleneic thieno[3,2-d]pyrimidines has been identified which potently inhibit the EGFR and ErbB-2 receptor tyrosine kinases. Synthetic modifications of the pyrrolidine carbamate moiety result in a range of effects on enzyme and cellular potency. In addition, the impact of the absolute stereochemical configuration on cellular potency and oral mouse pharmacokinetics is described.

2009-01-01

76

Enhanced ?₂-adrenergic receptor (?₂AR) signaling by adeno-associated viral (AAV)-mediated gene transfer

Dramatic Effects of 2-Bromo-5,6-Dichloro-1-?-d-Ribofuranosyl Benzimidazole Riboside on the Genome Structure, Packaging, and Egress of Guinea Pig Cytomegalovirus

Backgroundb2;₂-Adrenergic receptors (b2;₂AR) play important regulatory roles in a variety of cells and organ systems and are important therapeutic...Full Text Available

77

Design, synthesis, and testing of difluoroboron derivatized curcumins as near infrared probes for in vivo detection of amyloid-? deposits

The halogenated benzimidazoles BDCRB (2-bromo-5,6-dichloro-1-b2;-d-riborfuranosyl benzimidazole riboside) and TCRB (2,5,6-trichloro-1-b2;-d-riborfuranosyl benzimidazole...Full Text Available

2004-02-01

78

Clavulanic Acid, a Novel Inhibitor of ?-Lactamases

Amyloid-b2; (Ab2;) deposits have been identified as key players in the progression of Alzheimer’s disease (AD). Recent evidence indicates that the deposits probably precede...Full Text Available

2009-10-28

79

A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice

Clavulanic acid, Z-(2R,5R)-3-(b2;-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0] heptane-2-carboxylic acid, has been shown to be an effective inhibitor of the b2;-lactamases of the...Full Text Available

1978-11-01

80

?₂ integrins are required for skin homing of primed T cells but not for priming naive T cells

Amyloid plaques are a characteristic feature in Alzheimer’s disease (AD). A novel non-toxic contrast agent is presented, Gd-DTPA-K6Ab2;1–30, which is homologous to Ab2;,...Full Text Available

2008-06-01

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81

this issue NASA Cloud Computing Platform: Nebula

b2;₂ integrins are of critical importance for leukocyte extravasation through vascular endothelia and for T cell activation. To elucidate the role of b2;₂ integrins...Full Text Available

2002-01-15

82

Modelling of tritium behavior in solid breeder blankets of conceptual fusion reactors

National Aeronautics and Space Administration. Issue 2. June 2010 this issue. Nebula: Cloud Computing p.1. Better Business with EA p.2 ...

83

Luminescent properties of Eu3+-activated Sr3B2SiO8: A red-emitting phosphor for white light-emitting diodes

1982. p. 1, Paper 11. United States Kessel, CE Jr. Univ. of California,

1982-03-28

84

Decay of the Ar 2s"-"1 and 2p"-"1 and Kr 3p"-"1 and 3d"-"1 hole states studied by photoelectron-ion coincidence spectroscopy

Single-phased Sr3B2SiO8:Eu3+ phosphor was prepared by a solid-state method at 1020 oC. The luminescence spectra showed that Sr3B2SiO8:Eu3+ phosphor can be effectively excited by near ultraviolet light (393 nm) and blue light (464 nm). When excited at 393 or 464 nm Sr3B2SiO8:Eu3+ exhibited the main emission peaks at 611 and 620 nm, which resulted from the supersensitive 5D0#->#7F2 transition of Eu3+. The luminescence intensity of Sr3B2SiO8:Eu3+ at 611 and 620 nm reached the maximum when the doping content of Eu3+ was 4.5 mol%. Its chromaticity coordinates (0.646, 0.354) were very close to the NTSC standard values (0.67, 0.33). Thus, Sr3B2SiO8:Eu3+ is considered to be an efficient red-emitting phosphor for long-UV InGaN-based light-emitting diodes. - Highlights: ? ...

2011-07-01

85

Lithium isotope separation by cryptand (2 sub(B), 2, 1) polymer

The decay channels of the Ar 2s"-"1 and 2p"-"1 and Kr 3p"-"1 and 3d"-"1 electronic hole states have been investigated by means of photoelectron-photoion coincidence measurements following innershell ionization using synchrotron radiation. With the method of final ion-charge resolving electron spectroscopy it has become possible to disentangle different contributions to the electron spectrum and to determine the decay probabilities P(nl"-"1#->#n+) of the above-mentioned hole states (nl"-"1) to the final ionic charge states n+. A high correlation with threefold or even fourfold charged ions has been found in all cases. Possible decay routes, via cascade or direct double Auger processes, are discussed on the basis of energy-level schemes calculated with the Hartree-Fock method. Special emphasis is laid on the examination of the Kr 3p"-"1 decay process, where the ...

2002-04-01

86

Twist-1 is a PPAR ?-inducible, negative feedback regulator of PGC-1 ? in brown fat metabolism

Single stage separation factors ..cap alpha.. have been determined for /sup 6/Li and /sup 7/Li between lithium ions in methanol and complexed ions with a cryptand (2 sub(B), 2, 1) polymer. The /sup 6/Li was concentrated in the cryptand. The separation factors were compared with the values of other chemical exchange systems. The maximum enrichment factor obtained was epsilon = 0.047 +- 0.002. The figure is one of the greatest in the chemical exchange reactions without valence change and almost 10 times larger than the values of ion exchangers. The variation in ..cap alpha.. depending on the chemical species was small in the non-aqueous system. High enrichment of lithium isotopes was expected to be achievable by means of the chromatographic application of the cryptand (2 sub(B), 2, 1).

1984-02-01

87

Tumor necrosis factor-? serum levels in healthy smokers and nonsmokers

SummaryBrown fat is specialized in energy expenditure, a process that is principally controlled by the transcriptional co-activator PGC-1b1;. Here we describe a molecular...Full Text Available

2009-04-03

88

Therapeutic Vaccination in Chronic Hepatitis B: Preclinical Studies in the Woodchuck

Background:Tobacco smoking is the most important risk factor for chronic obstructive pulmonary disease (COPD) development. Inhaled cigarette smoke can induce tumor necrosis factor-b1;...Full Text Available

2010-01-01

89

The oncogenic transforming potential of the passage of single ? particles through mammalian cell nuclei

Recommended treatment of chronic hepatitis B with interferon-b1; and/or nucleos(t)ide analogues does not lead to a satisfactory result. Induction of HBV-specific T cells by therapeutic...Full Text Available

2010-01-01

90

The impact of linac output variations on dose distributions in helical tomotherapy

Domestic, low-level exposure to radon gas is considered a major environmental lung-cancer hazard involving DNA damage to bronchial cells by b1; particles from radon progeny. At domestic exposure...Full Text Available

1999-01-05

91

The effect of an ?-globulin preparation and of polyribonuclease complexes on humoral antibody formation

It has been suggested for quality assurance purposes that linac output variations for helical tomotherapy (HT) be within �b1;2% of the long-term average. Due to cancellation of systematic...Full Text Available

2008-01-21

92

The Melanocortin 3 Receptor: A Novel Mediator of Exercise-Induced Inflammation Reduction in Postmenopausal Women?

The effects of bovine b1;-globulin (BAG), bovine-ribonuclease serum albumin (BSA-RNase) and polyribonuclease (poly-RNase) complexes on the primary response of rodents to sheep erythrocytes have...Full Text Available

1968-06-01

93

The Effect of 5?-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen and Sexual Function in Healthy Young Men

The purpose of this study was to determine whether resistance exercise training-induced reductions in inflammation are mediated via melanocortin 3 receptor expression in obese (BMI 32.7 �b1; 3.7)...Full Text Available

94

The Biosynthesis of ?-Aminolevulinic Acid in Chlorella¹

PurposeDutasteride and finasteride are 5b1;-reductase inhibitors that dramatically decrease serum levels of dihydrotestosterone. Because androgens...Full Text Available

2008-06-01

95

Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties

When autotrophically growing cultures of Chlorella are treated with levulinic acid, δ-aminolevulinic acid is excreted into the medium, providing a direct demonstration of b1;-aminolevulinic...Full Text Available

1970-04-01

96

British Library Electronic Table of Contents (United Kingdom)

A series of thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties were synthesized starting from 5-[4-(4-X-phenylsulfonyl)phenyl]-4H-1,2,4-triazole-3-thioles 3a-c, X=H, Cl, Br. Thus, alkylation of 1,2,4-triazoles 3 with phenacyl bromide or 4-bromophenacyl bromide afforded S-substituted 1,2,4-triazoles 4, 5. These new intermediates 4 and 5, in the presence of H2SO4 (c), were cyclized to 2-[4-(4-X-phenylsulfonyl)phenyl]-6-(4-Y-phenyl)[1,3]thiazolo[3,2-b]-[1, 2,4]-triazoles 6, 7 (I) and not to isomeric thiazolo[2,3-c][1,2,4]-triazoles 6, 7 (II). The newly synthesized compounds were characterized by IR, 1H, 13C NMR and elemental analysis. MS spectra confirmed the formation of thiazolo[3,2-b][1,2,4]triazole 6, 7 (forms I) in detriment of [2,3-c] isomeric compounds (forms II). Th...

2009-01-01

97

Structure of lipid bilayers

Stem Cell Therapies Benefit Alport Syndrome

The quantitative experimental uncertainty in the structure of fully hydrated, biologically relevant, fluid (L_b1;) phase lipid bilayers has been too large to...Full Text Available

2000-11-10

98

Regulation and Function of Escherichia coli Sugar Efflux Transporter A (SetA) during Glucose-Phosphate Stress?

Patients with Alport syndrome progressively lose renal function as a result of defective type IV collagen in their glomerular basement membrane. In mice lacking the b1;3 chain of type IV collagen...Full Text Available

2009-11-01

99

Production, Purification, and Characterization of ?-Galactosidase from Monascus pilosus

Accumulation of certain nonmetabolizable sugar-phosphates (including b1;-methyl glucoside-6-phosphate) in Escherichia coli is growth inhibitory and elicits the glucose-phosphate...Full Text Available

2011-01-01

100

Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol

A Monascus pilosus strain was selected for production of intracellular b1;-galactosidase. Optimum conditions for mycelial growth and enzyme induction were determined. Galactose...Full Text Available

1986-11-01

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101

Preferential induction of cytochrome P450 1A1 over cytochrome P450 1B1 in human breast epithelial cells following exposure to quercetin

PurposeRadiation-induced heart disease (RIHD) is a severe side effect of thoracic radiotherapy. This study examined the effects of PTX and b1;-tocopherol on...Full Text Available

2008-09-01

102

British Library Electronic Table of Contents (United Kingdom)

Estrogen metabolism is suggested to play an important role in estrogen-induced breast carcinogenesis. Epidemiologic studies suggest that diets rich in phytoestrogens are associated with a reduced risk of breast cancer. Phytoestrogens are biologically active plant compounds that structurally mimic 17b-estradiol (E2). We hypothesize that phytoestrogens, may provide protection against breast carcinogenesis by altering the expression of estrogen-metabolizing enzymes cytochrome P450 1A1 (Cyp1A1) and 1B1 (Cyp1B1). Cyp1A1 and Cyp1B1 are responsible for the metabolism of E2 to generate 2-hydroxyestradiol (2-OHE2) and 4-hydroxyestradiol (4-OHE2), respectively. Studies suggest that 2-OHE2 and 2-methoxyestradiol may protect against breast carcinogenesis, while 4-OHE2 is carcinogenic in rodent models....

2008-01-01

103

Orgasm is preserved regardless of ejaculatory dysfunction with selective ?1A-blocker administration

Metal Ions-Stimulated Iron Oxidation in Hydroxylases Facilitates Stabilization of HIF-1? Protein

We evaluated whether ejaculatory dysfunction induced with a selective b1;1A-blocker influenced orgasm. Fifteen healthy male volunteers took silodosin or a placebo in a randomized, double-blind...Full Text Available

2009-09-01

104

Listeria monocytogenes Infection Induces Prosurvival Metabolic Signaling in Macrophages?

The exposure of cells to several metal ions stabilizes HIF-1b1; protein. However, the molecular mechanisms are not completely understood. They may involve inhibition of hydroxylation by either...Full Text Available

2009-02-01

105

Interaction of Heparins and Dextran Sulfates with a Mesoscopic Protein Nanopore

Host cells use metabolic signaling through the LXRb1; nuclear receptor to defend against Listeria monocytogenes infection. 25-Hydroxycholesterol is a natural ligand of LXRs that...Full Text Available

2011-04-01

106

Independence of extracellular tortuosity and volume fraction during osmotic challenge in rat neocortex

AbstractA mechanism of how polyanions influence the channel formed by Staphylococcus aureus b1;-hemolysin is described. We demonstrate that the probability of several...Full Text Available

2009-12-02

107

Finasteride-Its Impact on Sexual Function and Prostate Cancer

The structural properties of brain extracellular space (ECS) are summarised by the tortuosity (λ) and the volume fraction (b1;). To determine if these two parameters were independent,...Full Text Available

2002-07-15

108

Enantioselective organocatalytic ?-sulfenylation of substituted diketopiperazines

Finasteride, a specific and competitive inhibitor of 5b1;-reductase enzyme Type 2, inhibits the conversion of testosterone to dihydrotestosterone (DHT). In adults, DHT acts as primary androgen...Full Text Available

2009-01-01

109

Crystallization and preliminary X-ray analysis of human liver ?-enolase

The asymmetric organocatalytic b1;-sulfenylation of substituted piperazine-2,5-diones is reported, with cinchona alkaloids as chiral Lewis bases and electrophilic sulfur transfer reagents....Full Text Available

2009-12-11

110

Critical role of SDF-1?-induced progenitor cell recruitment and macrophage VEGF production in the experimental corneal neovascularization

Enolase is a multifunctional enzyme that plays important roles in many biological and disease processes. b1;-Enolase from human liver (hENO1) was expressed as a soluble protein and purified by...Full Text Available

111

Characteristics of Galacturonic Acid Oligomers as Elicitors of Casbene Synthetase Activity in Castor Bean Seedlings 1

PurposeTo address the roles of the stromal derived factor-1 (SDF-1) b1; in the course of experimental corneal neovascularization (CNV).MethodsCNV...Full Text Available

112

Calcium/Calmodulin-Dependent Protein Kinase II Mediates Hippocampal Glutamatergic Plasticity During Benzodiazepine Withdrawal

Partial digestion of polygalacturonic acid with polygalacturonase isolated from Rhizopus stolonifer produces a mixture of b1;-1,4-d-galacturonide oligomers which act...Full Text Available

1984-04-01

113

Butyrate Induces Expression of 17?-Hydroxysteroid Dehydrogenase Type 1 in HT29 and SW707 Colorectal Cancer Cells

Benzodiazepine withdrawal anxiety is associated with potentiation of b1;-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPAR) currents in hippocampal CA1 pyramidal...Full Text Available

2010-08-01

114

British Library Electronic Table of Contents (United Kingdom)

Epidemiological studies have revealed that butyrate and 17?-estradiol (E2) may decrease the incidence of colorectal cancer (CRC). In peripheral tissue, E2 can be produced locally by 17?-hydroxysteroid dehydrogenase 1 (HSD17B1) estrone (E1) reduction. Using quantitative real-time polymerase chain reaction and western blotting analysis, we found that sodium butyrate significantly upregulates HSD17B1 long and short transcripts and protein levels in HT29 and SW707 CRC cells. Chromatin immunoprecipitation analysis showed that upregulation of these transcript levels correlated with an increase in binding of Polymerase II to proximal and distal promoters of HSD17B1. Moreover, we observed that upregulation of HSD17B1 protein levels was associated with increased conversion of E1 to E2 in HT29 and S...

2011-01-01

115

Autoantibodies to BRAF, a new family of autoantibodies associated with rheumatoid arthritis

Ammonia adsorption on the C_3_0B_1_5N_1_5 heterofullerene: DFT study of nuclear magnetic shielding and electric field gradient tensors of N and B nuclei

IntroductionBRAF (v raf murine sarcoma viral oncogene homologue B1) is a serine-threonine kinase involved in the mitogen-activated protein kinase (MAPK) signalling pathway, known...Full Text Available

2010-01-01

116

Alpha-Hemoglobin-Stabilizing Protein: An Erythroid Molecular Chaperone

Ammonia adsorption on the external surface of C_3_0B_1_5N_1_5 heterofullerene was studied using density functional calculations. Three models of the ammonia-attached C_3_0B_1_5N_1_5 together with the perfect model were optimized at the B3LYP/6-31G"* level. The optimization process reveals that dramatic influences occurred for the geometrical structure of C_3_0B_1_5N_1_5 after ammonia adsorption; the B atom relaxes outwardly and consequently the heterofullerene distorts from the spherical form in the adsorption sites. The chemical shielding (CS) tensors and nuclear quadrupole coupling constants of B and N nuclei were calculated at the B3LYP/6-311G"*"* level. Our calculations reveal that the B atom is chemically bonded to NH_3 molecule. The B atom in the NH_3-attached form has the largest chemical shielding isotropic (CSI) value among the other boron nuclei. The ...

2011-04-01

117

ADP-Glucose Pyrophosphorylase, a Regulatory Enzyme for Bacterial Glycogen Synthesis

Alpha-hemoglobin-stabilizing protein (AHSP) is an erythroid-specific protein that acts as a molecular chaperone for the free b1; chains of hemoglobin. Evidence strongly suggests...Full Text Available

2011-01-01

118

A homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, ? cell hyperplasia, and islet cell tumor

The accumulation of b1;-1,4-polyglucans is an important strategy to cope with transient starvation conditions in the environment. In bacteria and plants, the synthesis of glycogen and starch occurs...Full Text Available

2003-06-01

119

A T to A base substitution and small deletions in the conalbumin TATA box drastically decrease specific in vitro transcription.

ObjectiveThe goal of the study was to investigate the genetic and molecular basis of a novel syndrome of marked hyperglucagonemia and pancreatic b1; cell hyperplasia...Full Text Available

2009-11-01

120

A Review of the Biochemistry, Metabolism and Clinical Benefits of Thiamin(e) and Its Derivatives

We have previously shown that a T to G transversion at the second T of the conalbumin "TATA" box drastically decreases specific initiation of transcription by RNA polymerase B (1). We now report that...Full Text Available

1981-04-24

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121

A Novel Form of Transcriptional Silencing by Sum1-1 Requires Hst1 and the Origin Recognition Complex

Thiamin(e), also known as vitamin B1, is now known to play a fundamental role in energy metabolism. Its discovery followed from the original early research on the ‘anti-beriberi factor’...Full Text Available

2006-03-01

122

A Conserved Role for Phosphoinositide-3-Kinase but Not Akt Signaling in Mitochondrial Adaptations that Accompany Physiological Cardiac Hypertrophy

In the yeast Saccharomyces cerevisiae, a and b1; mating-type information is stored in transcriptionally silenced cassettes called HML and HMR....Full Text Available

2001-05-01

123

?-Blocker Use Is Associated With Decreased Risk of Sexual Dysfunction

Physiological cardiac hypertrophy is associated with mitochondrial adaptations that are characterized by activation of PGC-1b1; and increased fatty acid oxidative (FAO) capacity. It is...Full Text Available

2007-10-01

124

Nanocrystallization of the amorphous Fe_1_4Ni_4_0Zr_7B_1_2 alloys studied by the Moessbauer spectroscopy

OBJECTIVESTo examine the association between b1;-blocker use and sexual dysfunction among men participating in a population-based cohort of...Full Text Available

2009-07-01

125

Moessbauer study of magnetic anisotropy in amorphous Fe_4_0Ni_3_8Mo_4B_1_8 (METGLAS 2628MB)

Formation of the soft magnetic nanostructure in amorphous Fe_1_4Ni_4_0Zr_7B_1_2 alloy due to heat treatment is studied by the Moessbauer, differential scanning calorimetry, and X-ray diffraction techniques. Annealing at temperatures 520-580 "oC leads to the formation of extremely soft nanocrystalline alloy as revealed by the rf-Moessbauer measurements. The superparamagnetic behaviour was observed for the alloy annealed at 620-640 "oC. At higher annealing temperatures good soft magnetic properties deteriorate. (author)

2001-09-23

126

The Pseudoreceptor BMP and Activin Membrane-bound Inhibitor Positively Modulates Wnt/?-Catenin Signaling*

The room-temperature anisotropy of amorphous Fe_4_0Ni_3_8Mo_4B_1_8 (METGLAS 2628MB) ribbons after various heat treatments has been studied by Moessbauer spectroscopy. The average magnetization direction becomes significantly more out-of-plane after heating above 650 K but below the crystallization temperature. X-ray diffractograms suggest an atomic rearrangement has occurred. (orig.).

127

Stabilization of ?-catenin induces pancreas tumor formation

The canonical Wnt/b2;-catenin pathway plays a pivotal role in regulating embryogenesis and tumorigenesis by promoting cell proliferation. BAMBI (BMP and activin membrane-bound inhibitor) has...Full Text Available

2008-11-28

128

Role of Estrogen Receptor-? in the Regulation of Claudin-6 Expression in Breast Cancer Cells

Background & Aimsb2;-catenin signaling within the canonical Wnt pathway is essential for pancreas development. However, the pathway is normally down-regulated...Full Text Available

2008-10-01

129

Renal functions in pediatric patients with beta-thalassemia major: relation to chelation therapy: original prospective study

PurposeIn our previous studies we showed that upregulating claudin-6 (CLDN6) expression may contribute to preventing breast cancer, and that 17b2;-estradiol induces a concentration-...Full Text Available

2011-03-01

130

Relation between regional and global systolic function in patients with ischemic cardiomyopathy after ?-Blocker therapy or revascularization

BackgroundIn b2;-thalassemia, profound anemia and severe hemosiderosis cause functional and physiological abnormalities in various organ systems. In recent years, there have...Full Text Available

131

Nuclear ? catenin as a potential prognostic and diagnostic marker in patients with colorectal cancer from Hong Kong

BackgroundTo assess the relationship between improved regional and global myocardial function in patients with ischemic cardiomyopathy in response to b2;-blocker therapy or...Full Text Available

132

Neutron shielding and constructional characteristics of a new type concrete and from borated clinker

Aims: To study the expression of nuclear b2; catenin in patients with colorectal cancer, colorectal adenoma, and colorectal polyps to elucidate its role in carcinogenesis, and its...Full Text Available

2003-12-01

133

Molecular and Kinetic Comparison of the Novel Extended-Spectrum ?-Lactamases CTX-M-25 and CTX-M-26

A boron containing cement, which can be used as nuclear shielding material, is produced at pilot plant scale applying two different methods. In the first method, the raw mixture of a normal portland cement is mixed with pre-calcined colemanite, a calcium borate mineral, and clinkerized in a rotary kiln (borated-clinker). In the second method, the colemanite is mixed with an admixture, which contains mainly limestone and marl, and burnt in the rotary kiln to obtain a borated-lime composite. The borated-lime composite is then added to the normal portland cement clinker up to 2% B_2O_3 content for shielding purpose. The results have shown that the borated-clinker contained untolerable amount of free lime resulting in a decrease in compressive strength. The addition of the borated-lime composite to the normal portland cement clinker up to 1% B_2O_3 content did not alter the setting time and the volume ...

1994-11-07

134

Molecular Epidemiology of Escherichia coli Producing Extended-Spectrum ?-Lactamases Isolated in Rome, Italy?

CTX-M-25 is a novel extended-spectrum b2;-lactamase isolated from a single Canadian Escherichia coli isolate. Susceptibility testing demonstrated that this enzyme confers resistance...Full Text Available

2004-12-01

135

Loss of ?-III spectrin leads to Purkinje cell dysfunction recapitulating the behaviour and neuropathology of SCA5 in humans

Escherichia coli strains producing extended-spectrum b2;-lactamases (ESBLs) are a major problem in many different hospitals worldwide, causing outbreaks as well as sporadic infections....Full Text Available

2008-01-01

136

Insulin and Glucagon Regulate Pancreatic ?-Cell Proliferation

Mutations in SPTBN2, the gene encoding b2;-III spectrin, cause spinocerebellar ataxia type 5 in humans (SCA5), a neurodegenerative disorder resulting in loss of motor...Full Text Available

2010-04-07

137

Influence of microenvironment on engraftment of transplanted ?-cells

Type 2 diabetes mellitus (T2DM) results from insulin resistance and b2;-cell dysfunction, in the setting of hyperglucagonemia. Glucagon is a 29 amino acid peptide hormone, which is secreted from...Full Text Available

138

Infected foot ulcers in male and female diabetic patients: a clinico-bioinformative study

Pancreatic islet transplantation into the liver provides a possibility to treat selected patients with brittle type 1 diabetes mellitus. However, massive early b2;-cell death increases the number...Full Text Available

2011-02-01

139

Identifying and validating biomarkers for Alzheimer's disease

BackgroundThe study aimed at (i) characterizing the mode of transmission of bla_CTX-Mand bla_TEM-1among extended-spectrum-b2;-lactamase...Full Text Available

140

Identification of CTX-M-Type Extended-Spectrum-?-Lactamase Genes Using Real-Time PCR and Pyrosequencing?

The identification and validation of biomarkers for diagnosing Alzheimer's disease (AD) and other forms of dementia are increasingly important. To date, ELISA measurement of b2;-amyloid(1–42),...Full Text Available

2011-01-01

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141

Identification of CTX-M-14 Extended-Spectrum ?-Lactamase in Clinical Isolates of Shigella sonnei, Escherichia coli, and Klebsiella pneumoniae in Korea

CTX-M extended-spectrum b2;-lactamases (ESBLs) are increasingly prevalent worldwide among Escherichia coli bacteria, mostly in community-acquired urinary tract infections. Finding...Full Text Available

2007-01-01

142

Genetic Variation at the Mitochondrial DNA 9-bp Repeat Locus in the Sakha of Siberia

CTX-M-14 b2;-lactamase was identified in a stool isolate of Shigella sonnei and in blood isolates of Escherichia coli (one isolate) and Klebsiella pneumoniae...Full Text Available

2001-10-01

143

Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages

... 16223, 16292, and 16295, which classify them as haplogroup W (Richards et al. 2000). The sample that was ... belonged to haplogroup B, 2 individuals belonged to haplogroup W, and 1 individual belonged to ...

144

Flexible responses to visual and olfactory stimuli by foraging Manduca sexta: larval nutrition affects adult behaviour

Dectin-1, the major b2;-glucan receptor in leukocytes, triggers an effective immune response upon fungal recognition. Here we use sortase-mediated transpeptidation, a technique that allows placement...Full Text Available

2011-08-23

145

Emergence of Enterobacteriaceae Isolates Producing CTX-M Extended-Spectrum ?-Lactamase in Austria

Here, we show that the consequences of deficient micronutrient (b2;-carotene) intake during larval stages of Manduca sexta are carried across metamorphosis, affecting adult behaviour....Full Text Available

2009-08-07

146

Effect of iron and boron carbide on the densification and mechanical properties of titanium diboride ceramics

Among 149 extended-spectrum b2;-lactamase (ESBL)-producing Enterobacteriaceae isolates collected from patients in southeast Austria from 1998 to 2004, 38 Escherichia coli...Full Text Available

2006-02-01

147

Effect of Li-Al co-doping on the energy gaps of MgB2

The effects of Fe and B_4C on the sintering behavior and mechanical properties of TiB_2 ceramics have been studied. Sintering was performed in an Ar atmosphere at 2000 degrees C using attrition-milled TiB_2 powder. When a small amount of Fe (0.5 wt%) was added, abnormal grain growth occurred and the sintered density was low. In the case of B_4C added along with 0.5 wt% Fe, however, abnormal grain growth was remarkably suppressed, and the sintered density was increased up to 95% of theoretical. But with excess Fe addition (5 wt%), B_4C grains did not act as a grain growth inhibitor, and B_4C grains were frequently trapped in large TiB_2 grains. The best mechanical properties were obtained for the TiB_2-10 wt% B_4C-0.5 wt% Fe ceramics, which exhibited a three-point bending strength of 400 MPa and a fracture toughness of ...

148

EPR and FT-IR spectroscopic studies of Bi2O3-B2O3-CuO glasses

We studied the effects of co-doping with Li and Al on the energy gaps of MgB2 by performing point-contact Andreev-reflection spectroscopy (PCAR) in polycrystalline Mg1-x(Al?Li1-?)xB2 samples with x?0.4. Even though the lattice parameters and the critical temperature of the compound simply scale with the effective Al content ?x, irrespective of the Li concentration, the energy gaps do not. In particular, for a given effective Al content, the comparison with Mg1-y(Al)yB2 with y = ?x shows that the ? bandgap is practically the same while the ? bandgap is higher. A clear gap merging is observed in the most doped sample (x = 0.4) when Tc<20 K. The results are discussed within the two-band Eliashberg theory and compared to the outcomes of first-principles calculations of the effects of Li and Al co-doping on the electronic structure of magnesium diboride.

2009-02-01

149

Dissemination of CTX-M-Type Extended-Spectrum ?-Lactamase Genes to Unusual Hosts

EPR and FT-IR absorption measurements have been performed for xCuO.(100-x)[2Bi2O3.B2O3] glass system, with 0?x?50 mol%. The mode in which the addition of the copper ions influences the structure of 2Bi2O3.B2O3 glass matrix was analyzed. The EPR absorption spectra revealed the presence in the glass structure of Cu2+ ions in axially distorted octahedral environments. EPR data pointed out the simultaneous presence of Cu2+ and Cu+ ionic species in the glasses with x?5 mol%. For x>10 mol%, the Cu2+ ions participate in the superexchange magnetic interactions, which increase with CuO content. The FT-IR spectra showed the presence of some bands that are assigned to vibrations of Bi-O bonds from BiO3 pyramidal and BiO6 octahedral units and B-O bonds from BO3 and BO4 units. The data obtained by these measurements reveal the structural changes in the 2Bi2O3.B2O3 glass ...

2008-10-01

150

Characterization of a Chromosomally Encoded Extended-Spectrum Class A ?-Lactamase from Kluyvera cryocrescens

A Citrobacter amalonaticus and a Morganella morganii producing the CTX-M-1 extended-spectrum b2;-lactamase (ESBL) were isolated from an area where this enzyme...Full Text Available

2005-08-01

151

Characterization of Terfestatin A, a New Specific Inhibitor for Auxin Signaling1[w

A chromosomally located b2;-lactamase gene, cloned and expressed in Escherichia coli from a reference strain of the enterobacterial species Kluyvera cryocrescens,...Full Text Available

2001-12-01

152

Characterization of Multidrug Resistant ESBL-Producing Escherichia coli Isolates from Hospitals in Malaysia

Terfestatin A (TrfA), terphenyl-b2;-glucoside, was isolated from Streptomyces sp. F40 in a forward screen for compounds that inhibit the expression of auxin-inducible...Full Text Available

2005-10-01

153

CTX-M-Type Extended-Spectrum ?-Lactamases in Italy: Molecular Epidemiology of an Emerging Countrywide Problem

The emergence of Escherichia coli that produce extended spectrum b2;-lactamases (ESBLs) and are multidrug resistant (MDR) poses antibiotic management problems....Full Text Available

2009-01-01

154

CTX-M ?-Lactamases in Escherichia coli from Community-acquired Urinary Tract Infections, Cambodia

A nationwide survey of extended-spectrum b2;-lactamase (ESBL) production among Enterobacteriaceae, carried out in 2003, showed that CTX-M-type enzymes have achieved a sizeable...Full Text Available

2006-08-01

155

Beyond AICA Riboside: In Search of New Specific AMP-activated Protein Kinase Activators

Despite the recent global spread of CTX-M b2;-lactamases in Escherichia coli isolates from community-acquired urinary tract infections (CA-UTIs), their dissemination has been...Full Text Available

2009-05-01

156

Behavioral Defects in Chaperone-Deficient Alzheimer's Disease Model Mice

Summary5-Aminoimidazole-4-carboxamide-1-b2;-d-ribofuranoside (AICA riboside) has been extensively used in vitro and in vivo to...Full Text Available

2009-01-01

157

Antagonistic crosstalk between APC and HIF-1?

Molecular chaperones protect cells from the deleterious effects of protein misfolding and aggregation. Neurotoxicity of amyloid-beta (Ab2;) aggregates and their deposition in senile plaques are...Full Text Available

158

Animal Models in Carotenoids Research and Lung Cancer Prevention1

Most colorectal cancers have mutations in the tumor suppressor APC. The best-understood function of APC is its participation in a protein complex that regulates the availability of b2;-catenin....Full Text Available

2011-05-15

159

Analysis of the Pharmacokinetic Interaction between Cephalexin and Quinapril by a Nonlinear Mixed-Effect Model

Numerous epidemiological studies have consistently demonstrated that individuals who eat more fruits and vegetables (which are rich in carotenoids) and who have higher serum b2;-carotene levels...Full Text Available

160

A Dominant Role for the Immunoproteasome in CD8⁺ T Cell Responses to Murine Cytomegalovirus

Oligopeptidic drugs such as b2;-lactams and angiotensin-converting enzyme inhibitors share the same carriers in humans and animals, which results in possible pharmacokinetic interactions. To model...Full Text Available

1998-06-01

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161

Vitamins B2 and B6 and genetic polymorphisms related to one-carbon metabolism as risk factors for gastric adenocarcinoma in the European prospective investigation into cancer and nutrition

Murine cytomegalovirus (MCMV) is an important animal model of human cytomegalovirus (HCMV), a b2;-Herpesvirus that infects the majority of the world's population and causes disease in neonates...Full Text Available

162

DEFF Research Database (Denmark)

B vitamins and polymorphisms in genes coding for enzymes involved in one-carbon metabolism may affect DNA synthesis and methylation and thereby be implicated in carcinogenesis. Previous data on vitamins B2 and B6 and genetic polymorphisms other than those involving MTHFR as risk factors for gastric cancer (GC) are sparse and inconsistent. In this case-control study nested within the European Prospective Investigation into Cancer and Nutrition cohort, cases (n = 235) and controls (n = 601) were matched for study center, age, sex, and time of blood sampling. B2 and B6 species were measured in plasma, and the sum of riboflavin and flavin mononucleotide was used as the main exposure variable for vitamin B2 status, whereas the sum of pyridoxal 5'-phosphate, pyridoxal, and 4-pyridoxic acid was used to define vitamin B6 status. In addition, we determined eight ...

2010-01-01

163

Genetic markers for lactation persistency in primiparous Australian dairy cows

British Library Electronic Table of Contents (United Kingdom)

Good performance in extended lactations of dairy cattle may have a beneficial effect on food costs, health, and fertility. Because data for extended lactation performance is scarce, lactation persistency has been suggested as a suitable selection criterion. Persistency phenotypes were calculated in several ways: P1 was yield relative to an approximate peak, P2 was the slope after peak production, and P3 was a measure derived to be phenotypically uncorrelated to yield and calculated as a function of linear regressions on test-day deviations of days in milk. Phenotypes P1, P2, and P3 were calculated for sires as solutions estimated from a random regression model fitted to milk yield. Because total milk yield, calculated as the sum of daily sire solutions, was correlated to P1 and P2 (r=0.30 ...

2010-01-01

164

Rapid, sensitive detection of Mycoplasma pneumoniae in simulated clinical specimens by DNA amplification.

Inherited sterility induced in progeny of gamma irradiated males and females spiny bollworm, Earias Insulana boisd ,effect on fecundity, fertility and mating

The polymerase chain reaction (PCR) was investigated as a means of diagnosing Mycoplasma pneumoniae infections. The target DNA sequence was a 375-bp segment of the P1 virulence protein. This DNA segment...Full Text Available

1992-12-01

165

General Disclaimer One or more of the Following Statements may ...

adult males and females, less than 24 hours old, of the spiny bollworm, Earias Insulana boisd. were irradiated with sub sterilizing doses of 50,80,100 and 150 gray (Gy). treated moths were out crossed with normal adults and observed for their ability to reproduce. inherited deleterious effects resulting from irradiation of p_1 moths were recorded for several generations. the reduction in both fecundity and egg viability increased by increasing the dose applied to p_1 adult moths .at all tested doses, the females were more radiosensitive than males, as for reduction in fecundity and egg viability. the progeny from irradiated parental females are not as sterile as the progeny from irradiated parental males. the reduction of egg hatching continued in the progeny of irradiated males through F_1 and to lesser extent through F_2 .on the other hand , irradiation of P_1 ...

2004-02-01

166

Population doses from beam-therapy in Japan, 1978, 3

P".1"..ues OrsedeNle+s Nose aid AtUn*&. SCITRAN. IL Tyr. of RN?/ ow PW" eNfew. Sox 5656. Trawlacio0. 12" ^CTona^ iro aut cce j!"d Space Administration ...

167

Treatment of low-frequency pulsating magnetic field on amorphous alloy Fe_7_8Si_9B_1_3

As a series of estimations of population doses and of risk estimates from medical exposures in Japan, the malignancy significant dose (MSD) and the fatal malignant risk from beam therapy were estimated based on a nationwide survey of radiotherapeutic treatments, using a malignancy significant factor and a weighting factor determined from the data on the cancer mortality among the atomic bomb survivors in Nagasaki. The effective dose was defined as a sum of the product of the weighting factor and the organ or tissue doses with respect to the malignant diseases. The organ or tissue doses were determined with ionization chambers placed at the positions of their center in a MixDp-phantom simulated lung tissues by a block of cork, using a telecobalt unit, a conventional X-ray unit and a medical linear accelerator. The organ or tissue doses were categorized into three dose components; namely 1) dose from useful beams; 2) scattered radiation dose from irradiated materials and 3) leakage ...

1981-01-01

168

Monoenergetic Gamma-Rays from Non-Minimal Kaluza-Klein Dark Matter Annihilations

Effect of low-frequency pulsating magnetic field on the microstructure and magnetic properties of amorphous alloy Fe_7_8Si_9B_1_3 were investigated. The temperature rise induced by the treatment was measured by a non-contact infrared thermometer. The crystallization behavior and microstructure of specimens were studied by Moessbauer spectroscopy and transmission electron microscope (TEM). Magnetic properties of the specimens were investigated by alternating gradient magnetometer (AGM). The results show that the low-frequency pulsating magnetic field can promote the single-phase crystallization of amorphous alloy Fe_7_8Si_9B_1_3. The frequency, f of applied field is from 10 to 40 Hz, magnetic field, H is from 0.02 to 0.04 T and treatment duration, t is from 180-300 s. The volume fraction of crystallization phase (#alpha#-Fe(Si), the grain size, 2-10 nm) is 3-7%. The temperature rise less than 7 deg. C. ...

2007-07-15

169

Hepatic aflatoxin B1-DNA adducts and TP53 mutations in patients with hepatocellular carcinoma despite low exposure to aflatoxin B1 in southern Japan

We investigate monoenergetic gamma-ray signatures of Z^1 dark matter annihilations in a non-minimal Universal Extra Dimensions model. The self-interactions of the non-Abelian Z^1 gauge boson give rise to a large number of contributing Feynman diagrams that do not exist for annihilations of the Abelian gauge boson B^1, which is the standard Kaluza-Klein dark matter candidate. We find that the annihilation rate is indeed considerably larger for the Z^1 than for the B^1. Even though relic density calculations indicate that the mass of the Z^1 should be larger than the mass of the B^1, the predicted fluxes are of the same order of magnitude. We compare our results to existing experimental limits, as well as to future sensitivities, for image air Cherenkov telescopes, and we find that the limits are reached already with a moderately large boost factor. However, the ...

2011-01-01

170

British Library Electronic Table of Contents (United Kingdom)

Abstract Background & aims: Hepatitis B or C virus infection is considered to be the main cause of hepatocellular carcinoma (HCC) in Japan. Aflatoxin B1 (AFB1) is a carcinogen associated with HCC in regions with high exposure. Mutations in codon 249, exon 7 are a hallmark of AFB1 exposure. Therefore, to clarify the role of AFB1 in hepatocarcinogenesis, we examined AFB1-DNA in liver tissue and sequenced TP53 in Japanese patients with HCC. Methods: Hepatocyte AFB1-DNA adducts were determined immunohistochemically and direct sequencing of TP53 was done to determine mutations in 188 of 279 patients who underwent hepatic resection for HCC. We assessed hepatitis C virus antibodies (HCV Ab) and HBSAg expression; patients without either were defined as having non-B non-C hepatocellular carcinoma (...

2011-01-01

171

Time-dependent infrared emission following photodissociation of nitromethane and chloropicrin.

Real-time neutron diffraction study of crystallization kinetics in amorphous Fe_7_8B_1_3Si_9 alloy

Nitromethane (CH(3)NO(2)) and its chlorinated analogue, chloropicrin (CCl(3)NO(2)), were photolyzed at 193, 248, and 266 nm, and the products were observed by time-dependent Fourier transform infrared emission spectroscopy. At 193 and 248 nm, the primary photodissociation pathway for nitromethane was cleavage of the C-N bond to produce CH(3) + NO(2)(A (2)B(2)). At 266 nm, weak emission was observed following photodissociation of nitromethane, but an infrared spectrum could not be obtained. The photodissociation of chloropicrin at 193 nm produced the analogous product channel CCl(3) + NO(2)(A (2)B(2)) in addition to several other product channels. At 248 and 266 nm, only CCl(3) + NO(2)(A (2)B(2)) was observed. The production of phosgene (CCl(2)O) from chloropicrin photodissociation was not observed in this study. PMID:16571044

2006-04-01

172

Measurements of bragg curve for 75 MeV/u "1"2C ion beam and its inactivation effect on melanoma cells

The transformation from the as-quenched amorphous to the crystalline state in Fe_7_8B_1_3Si_9 alloy has been investigated using a new-type neutron diffractometer. The time resolved diffraction patterns clearly show that this alloy crystallizes into FeSi alloy and Fe_2B in that order. The time evolution of these crystalline phases can be analyzed by the Kolmogorov-Johnson-Mehl-Avrami equation with the exponent of about 2.5 over a wide temperature range. This suggests that the crystallization occurs by the diffusion-controlled growth with a constant nucleation rate. The scaling behavior in the crystallization kinetics is also discussed. (author).

1987-01-01

173

Inhibition of heat shock protein 27 (HspB1) tumorigenic functions by peptide aptamers

Relative doses of 75 MeV/u "1"2C ion beam after passing through different thickness of degraders were measured with the double ionization chamber method. The degrader's thickness equalized to penetration depth of the beam in water and its Bragg curve were obtained. The measured Bragg curve is compared with that calculated based on a model set up by the authors. Meanwhile, the inactivation effect of the ion beam passing through different thickness of degraders on melanoma (B_1_6) cells was measured, and the corresponding survival fraction data for B_1_6 cells were acquired

1998-08-01

174

British Library Electronic Table of Contents (United Kingdom)

Human heat shock protein 27 (Hsp27, HspB1) is an anti-apoptotic protein characterized for its tumorigenic and metastatic properties, and now referenced as a major therapeutic target in many types of cancer. Hsp27 biochemical properties rely on a structural oligomeric and dynamic organization. Downregulation by small interfering RNA or inhibition with dominant-negative mutant have proven their efficiency to counteract the anti-apoptotic and protective properties of Hsp27. In this study, we report the isolation and characterization of Hsp27-targeted molecules interfering with its structural organization. Using the peptide aptamer (PA) strategy, we isolated PAs that specifically interact with Hsp27 and not with the other members of the small heat shock protein family. In mammalian cell cultur...

2011-01-01

175

Revenue management: the impact on business-to-business relationships

British Library Electronic Table of Contents (United Kingdom)

Purpose - This paper aims to explore the links between revenue management and business-to-business (B2B) relationships and explains how revenue management can both support and damage B2B relationships. Design/methodology/approach - A single case study method was employed to conduct qualitative research into a company and its key accounts. In-depth data were collected from three divergent sources (company revenue managers, company account managers and nine of the company's key accounts) through semi-structured interviews, observations and document studies. Findings - The research findings reveal that from the company's perspective, managers acknowledge that revenue management has positively influenced the process of identifying and analysing key account activities and conducting contractual...

2009-01-01

176

Mechanical properties, interface reactions and transport current densities of multi-core MgB_2/Ti/Cu/SS wire

Studies on inherited sterility induced in the progeny of gamma irradiated cotton leaf worm, Spodoptera littorals (Boisd.)

Multi-core MgB_2/Ti/Cu/SS composite wire has been made by the in situ approach. Mechanical properties, interdiffusion reactions and critical currents were studied after heat treatments at temperatures between 500 and 850 "0C. Cu diffusion into the Ti layer occurs for all samples, resulting in the formation of intermetallic compounds at the Cu/Ti interface. EDX analysis has revealed the temperature dependence of all interface reactions. In spite of element reactions the critical current densities 10"5 A cm"-"2 and 10"4 A cm"-"2 were measured in liquid helium at magnetic fields 5 T and 9.5 T, respectively. 10"4 A cm"-"2 at 20 K is measured in an external field of 4 T.

2010-07-01

177

Inherited Sterility in Progeny of Gamma-Irradiated Spiny Bollworm, Earias Insulana Boisd

Full - grown pupae of the cotton leaf worm Spodoptera littorals (Boisd.) were gamma - irradiated with low doses of 25,50,75, or 100 Gy for male line and with 50 or 100 Gy for female line . The effects on reproduction, development and sex ratio were the biological aspects studied among P1,F1,F2 and F 3 generations . Also, the effects of dose accumulation applied grown male pupae through two or three filial generations and the retarded influence on their F1,F2,and F 3 progeny were examined. In another trial the histological examinations for ovaries and testes of irradiated parents and for their generation were made . The F1 males were more sterile than irradiated parental males while F1 females were more fertile than their irradiated parental females. Irradiation of P1 males did not clearly affect neither the percentage of mated females nor the average number of spermatophores per mated female among the ...

178

The hrpK Operon of Pseudomonas syringae pv. tomato DC3000 Encodes Two Proteins Secreted by the Type III (Hrp) Protein Secretion System: HopB1 and HrpK, a Putative Type III Translocator

The inherited sterility of the spiny bollworm Earias Insulana Boisd. Irradiated as parental male adults, with sub sterilizing doses of 100-200 Gy has been studied throughout three successive generations. In general, the female fecundity decreased at the three doses of irradiations (100, 150 and 200 Gy) throughout P_1. F_1, F_2 and F_3 generations as compared to control. The reduction was insignificant in all treatments with some exceptions at 200 Gy, in the parental generation and 150 and 200 Gy bin F_2 generation. Egg hatch of the parental generation was obviously reduced at 100, 150 and 200 Gy treatments as compared to the control. The progeny of F_1 males were evidently more sterile than their irradiated male parents. The effect continued in the F_2, population, however F_3 males almost regained their fertility. Irradiation of P_1 males did not greatly affect mating ability among ...

1999-01-01

179

The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in Scaffold Attachment Factor B1 deficient mice

Pseudomonas syringae is a gram-negative bacterial plant pathogen that is dependent on a type III protein secretion system (TTSS) and the effector proteins it translocates into plant...Full Text Available

2005-01-01

180

Testosterone Depletion by Castration May Protect Mice from Heat-Induced Multiple Organ Damage and Lethality

Werner syndrome (WS) is a rare disorder characterized by the premature onset of several pathologies associated with aging. The gene responsible for WS codes for a RecQ-type DNA helicase and is believed...Full Text Available

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181

Terpenoid-based defenses in conifers: cDNA cloning, characterization, and functional expression of wound-inducible (E)-?-bisabolene synthase from grand fir (Abies grandis)

When the vehicle-treated, sham-operated mice underwent heat stress, the fraction survival and core temperature at +4 h of body heating were found to be 5 of 15 and 34.4°C �b1; 0.3°C,...Full Text Available

2010-01-01

182

Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation

(E)-b1;-Bisabolene synthase is one of two wound-inducible sesquiterpene synthases of grand fir (Abies grandis), and the olefin product of this cyclization reaction...Full Text Available

1998-06-09

183

Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole

BackgroundAdipokines, e.g. TNFb1;, IL-6 and leptin increase insulin resistance, and consequent hyperinsulinaemia influences breast cancer progression. Beside its mitogenic...Full Text Available

184

Scaling properties of cell and organelle size

Two novel crystal structures of Zea mays protein kinase CK2b1; catalytic subunit, one in complex with the specific inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) and another...Full Text Available

2001-11-01

185

Replication, Pathogenesis and Transmission of Pandemic (H1N1) 2009 Virus in Non-Immune Pigs

How size is controlled is a fundamental question in biology. In this review, we discuss the use of scaling relationships—for example, power-laws of the form y∝x^b1;—to...Full Text Available

2010-04-01

186

Quality assurance requirements for the computer software and safety analyses

The declaration of the human influenza A pandemic (H1N1) 2009 (H1N1/09) raised important questions, including origin and host range b;1],...Full Text Available

187

Neuroactive steroids have multiple actions to potentiate GABA_A receptors

The requirements are given as placed on the development, procurement, maintenance, and application of software for the creation or processing of data during the design, construction, operation, repair, maintenance and safety-related upgrading of nuclear power plants. The verification and validation processes are highlighted, and the requirements put on the software documentation are outlined. The general quality assurance principles applied to safety analyses are characterized. (J.B.). 1 ref.

188

MicroRNAs Regulate Human Hepatocyte Nuclear Factor 4?, Modulating the Expression of Metabolic Enzymes and Cell Cycle*

The effects of neuroactive steroids on the function of GABA_A receptors were studied using cell-attached records of single channel activity recorded from HEK293 cells transfected with b1;1...Full Text Available

2004-07-01

189

Immunohistochemical localization of low density lipoprotein receptor-related protein 1 and ?₂-Macroglobulin in retinal and choroidal tissue of proliferative retinopathies

Hepatocyte nuclear factor (HNF) 4b1; is a key transcription factor regulating endo/xenobiotic-metabolizing enzymes and transporters. We investigated whether microRNAs are involved in the regulation...Full Text Available

2010-02-12

190

DIMINISHED DEGRADATION OF MYELIN BASIC PROTEIN BY ANTI-SULFATIDE ANTIBODY AND INTERFERON-? IN MYELIN FROM GLIA MATURATION FACTOR-DEFICIENT MICE

The immunolocalization of the low density lipoprotein receptor-related protein 1 (LRP1) and its ligand alpha 2-Macroglobulin (b1;₂M) was examined in tissues from human donor...Full Text Available

2010-08-01

191

Complete Nucleotide Sequence of an Exogenously Isolated Plasmid, pLB1, Involved in ?-Hexachlorocyclohexane Degradation?

In this study we show the effect of anti-sulfatide (RmAb) antibodies and inflammatory cytokines, TNF-b1; and IFN-γ in inducing myelin basic protein (MBP) degradation in myelin...Full Text Available

2007-06-01

192

Characterization of a novel plasmid-like element in Neurospora crassa derived mostly from the mitochondrial DNA.

The b1;-proteobacterial strain Sphingobium japonicum UT26 utilizes a highly chlorinated pesticide, γ-hexachlorocyclohexane (γ-HCH), as a sole source of carbon...Full Text Available

2006-11-01

193

Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed

We have identified a plasmid-like element within mitochondria of Neurospora crassa strain stp-B1. It is derived from the EcoRI-4 and EcoRI-6 regions of the mitochondrial DNA, and an additional 124 bp...Full Text Available

1990-10-11

194

Alternative mRNA Splicing Produces a Novel Biologically Active Short Isoform of PGC-1?*

In the isolated rat mesenteric bed, the 1 min perfusion with 100 nm anandamide, a concentration that did not evoke vasorelaxation, elicited an acute release of 165.1 �b1; 9.2 pmol nitric...Full Text Available

2005-10-15

195

The transcriptional co-activator PGC-1b1; regulates functional plasticity in adipose tissue by linking sympathetic input to the transcriptional program of adaptive thermogenesis. We report here...Full Text Available

2009-11-20

196

Activation of Metallothioneins and ?-Crystallin/sHSPs in Human Lens Epithelial Cells by Specific Metals and the Metal Content of Aging Clear Human Lenses

PurposePrevious studies have demonstrated that in 129b1;3Cx46^−/− mice, age-related nuclear cataract is formed. In...Full Text Available

2007-06-01

197

?_1A/B-Knockout mice explain the native ?_1D-adrenoceptor's role in vasoconstriction and show that its location is independent of the other ?₁-subtypes

PurposeTo identify those metallothionein and b1;-crystallin/small heat-shock genes induced by toxic metals in human lens cells and to evaluate...Full Text Available

2003-02-01

198

?₁-Fetoprotein Transcription Factor (FTF)/Liver Receptor Homolog-1 (LRH-1) Is an Essential Lipogenic Regulator

Background and purpose:Theoretically, three b1;₁-adrenoceptor subtypes can interact at the signalling level to alter vascular contraction or at the molecular level...Full Text Available

2009-12-01

199

Particle-hole strength excited in the /sup 40/Ca(p,n)/sup 40/Sc reaction at 134 MeV

b1;₁-Fetoprotein transcription factor (FTF), also known as liver receptor homolog 1 (LRH-1) is highly expressed in liver and intestine, where it is implicated in the regulation...Full Text Available

2010-04-01

200

Effect of some tripodal bipyrazolic compounds on C38 steel corrosion in hydrochloric acid solution

The /sup 40/Ca(p,n)/sup 40/Sc reaction was studied at 134 MeV. Neutron energy spectra were measured by the time-of-flight technique with resolutions of 220 keV at angles from 0"0 to 41"0 and 415 keV out to 62"0. The 2"-,3"-,4"-,5"- band of states based on the (f/sub 7/2/,d/sub 3/2//sup -1/) 1p1h structure was observed at low excitation energies, in good agreement with known analog states in /sup 40/Ca and /sup 40/K. The shapes of the cross-section and analyzing-power angular distributions are in good agreement with distorted-wave impulse-approximation calculations using simple 1p1h (Tamm-Dancoff approximation) shell-model wave functions. A relatively strong transition to a state at E/sub x/ = 2.3 MeV with L = 3 is identified tentatively as a 4"- state with the predominant 1p1h structure (1f/sub 7/2/,2s/sub 1/2//sup -1/).

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201

British Library Electronic Table of Contents (United Kingdom)

The corrosion inhibition of C38 steel in molar HCl by N,N-bis[2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl]buthylamine (P1) and 5-{N,N-bis[2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl] amino} pentanol (P2) has been investigated at 308?K using electrochemical and weight loss measurements. Measurements show that these compounds act as good inhibitors without changing the mechanism of the corrosion process. Moreover, the inhibiting efficiency increases with the increase in concentration of the studied inhibitors. Compound P2 showed better protection properties even at relatively higher temperatures when compared to P1. The associated activation corrosion and free adsorption energies have been determined. P1 and P2 are adsorbed on the C38 steel surface according to a Langmuir isotherm adsorption model.

2010-01-01

202

Compressed Counting

XRF and PIXE method as trols for the element analysis of metallic glasses

Counting is among the most fundamental operations in computing. For example, counting the pth frequency moment has been a very active area of research, in theoretical computer science, databases, and data mining. When p=1, the task (i.e., counting the sum) can be accomplished using a simple counter. Compressed Counting (CC) is proposed for efficiently computing the pth frequency moment of a data stream signal A_t, where 0= 0, which includes the strict Turnstile model as a special case. For natural data streams encountered in practice, this restriction is minor. The underly technique for CC is what we call skewed stable random projections, which captures the intuition that, when p=1 a simple counter suffices, and when p = 1+/\\Delta with small \\Delta, the sample complexity of a counter system should be low (continuously as a function of \\Delta). We show at ...

2008-01-01

203

XRF and PIXE analysis of metallic glasses

The radionuclide X-ray fluorescence and particle induced X-ray emission methods were used for rapid and nondestructive analysis of metallic glasses. The methods were compared for accuracy and precision with the atomic absorption method. Some results of the analyses of Fe_xNi_8_0_-_xB_2_0 materials are briefly reviewed. The distribution of elements along the width as well as the length and a qualitative analysis of the composition of material surfaces are considered. (author).

1986-01-01

204

Widespread Dissemination of Aminoglycoside Resistance Genes armA and rmtB in Klebsiella pneumoniae Isolates in Taiwan Producing CTX-M-Type Extended-Spectrum ?-Lactamases ?

Radionuclide X-ray fluorescence and particle induced X-ray emission methods were used for a rapid and nondestructive analysis of metallic glasses. The methods are compared in accuracy and precision with the atomic absorption method. Some results of analyses of Fe_xNi_8_0_-_xB_2_0 materials are briefly reviewed. The distribution of elements along the width and length, and a qualitative analysis of the composition of material surfaces are considered. (author) 3 refs.

1987-05-01

205

Transforming growth factor-? signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung

Among 235 extended-spectrum b2;-lactamase-producing Klebsiella pneumoniae (ESBL) isolates collected from a nationwide surveillance performed in Taiwan, 102 (43.4%) were...Full Text Available

2009-01-01

206

TGFB1-Induced Extracellular Expression of TGFBIp and Inhibition of TGFBIp Expression by RNA Interference in a Human Corneal Epithelial Cell Line

Hypoxia causes abnormal neonatal pulmonary artery remodeling (PAR) and inhibition of alveolar development (IAD). Transforming growth factor (TGF)-b2; is an important regulator of lung development...Full Text Available

2008-07-01

207

Purpose.To report the increased production of extracellular transforming growth factor b2;-induced protein (TGFBIp) by human corneal epithelial cells (HCECs) after induction...Full Text Available

2011-02-01

208

Sinterable powders

Silver nanoparticles inhibit VEGF-and IL-1?-induced vascular permeability via Src dependent pathway in porcine retinal endothelial cells

A description is given of sinterable powders and methods of producing sintered products using such powders. The powders consist of (a) a particulate ceramic material, e.g. SiC, having specified particle size and surface area; (b) a carbon source material, e.g. sugar or a phenol-formaldehyde resin; and (c) a residue from a solution of H3BO3, B2O3, or mixtures of these as sintering aid. (U.K.).

209

Polygalacturonase ?-Subunit Antisense Gene Expression in Tomato Plants Leads to a Progressive Enhanced Wound Response and Necrosis in Leaves and Abscission of Developing Flowers

The aim of this study is to determine the effects of silver nanoparticles (Ag-NP) on vascular endothelial growth factor (VEGF)-and interleukin-1 beta (IL-1b2;)-induced vascular permeability, and...Full Text Available

210

Physiological effects of manipulating the level of insulin-degrading enzyme in insulin-producing cells of Drosophila

Tomato (Lycopersicon esculentum var. Better Boy) plants were transformed with a tomato leaf wound-inducible polygalacturonase (PG) b2;-subunit gene in the antisense orientation...Full Text Available

2003-10-01

211

Nationwide Survey of CTX-M-Type Extended-Spectrum ?-Lactamases among Klebsiella pneumoniae Isolates in Slovenian Hospitals ?

Insulin-degrading enzyme (IDE) degrades insulin and other peptides, including the Ab2; peptide of Alzheimer’s disease. However, the mechanism by which IDE acts on its substrates...Full Text Available

2011-01-01

212

Molecular identification of CTX-M and ^blaOXY/K1 ?-lactamase genes in Enterobacteriaceae by sequencing of universal M13-sequence tagged PCR-amplicons

Among 177 extended-spectrum b2;-lactamase-producing Klebsiella pneumoniae isolates collected from 11 Slovenian hospitals in 2005 and 2006, 60 (34%), from eight hospitals,...Full Text Available

2009-01-01

213

Medical i2b2 NLP Smoking Challenge: The A-Life System Architecture and Methodology

BackgroundPlasmid encoded ^blaCTX-M enzymes represent an important sub-group of class A b2;-lactamases causing the ESBL phenotype which is increasingly...Full Text Available

214

Klebsiella pneumoniae Strains Producing Extended-Spectrum ?-Lactamases in Spain: Microbiological and Clinical Features^?

We describe the architecture of LifeCode® (A-Life Medical, Inc.), a natural language processing system for free-text clinical information extraction, our methodology in applying LifeCode®...Full Text Available

2008-01-01

215

Kinetic Parameters of Efflux of Penicillins by the Multidrug Efflux Transporter AcrAB-TolC of Escherichia coli?

Extended-spectrum b2;-lactamases (ESBL) of the CTX-M, SHV, and TEM families were recognized in 76 (67%), 31 (27%), and 6 (5%) isolates, respectively, among 162 ESBL-producing Klebsiella...Full Text Available

2011-03-01

216

Isomerization of 1-O-Indol-3-Ylacetyl-?-d-Glucose ¹

The multidrug efflux transporter AcrAB-TolC is known to pump out a diverse range of antibiotics, including b2;-lactams. However, the kinetic constants of the efflux process, needed for the quantitative...Full Text Available

2010-05-01

217

Interferon-? expressed by a rabies virus-based HIV-1 vaccine vector serves as a molecular adjuvant and decreases pathogenicity

The first compound in the series of reactions leading to the ester conjugates of indole-3-acetic acid (IAA) in kernels of Zea mays sweet corn is the acyl alkyl acetal, 1-O-indol-3-ylacetyl-b2;-d-glucose...Full Text Available

1990-09-01

218

Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages

Type I interferon is important in anti-viral responses and in coordinating the innate immune response. Here we explore the use of interferon-b2; to adjuvant the response to a rabies virus...Full Text Available

2008-12-20

219

Highly Ordered Spatial Organization of the Structural Long Noncoding NEAT1 RNAs within Paraspeckle Nuclear Bodies

LRP1 is a type-1 transmembrane receptor that mediates the endocytosis of diverse ligands. LRP1 b2;-chain proteolysis results in release of sLRP1 that is present in human plasma. In this study,...Full Text Available

2010-10-01

220

Growth differentiation factor-9 stimulates progesterone synthesis in granulosa cells via a prostaglandin E₂/EP2 receptor pathway

Paraspeckles (PSPs) are nuclear bodies associated with the retention in the nucleus of specific mRNAs. Two isoforms of a long noncoding RNA (NEAT1_v1/Menε and NEAT1_v2/Menb2;)...Full Text Available

2010-11-15

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221

First Report of the Emergence of CTX-M-Type Extended-Spectrum ?-Lactamases (ESBLs) as the Predominant ESBL Isolated in a U.S. Health Care System?

Growth differentiation factor-9 (GDF-9), an oocyte-secreted member of the transforming growth factor b2; superfamily, progesterone receptor, cyclooxygenase 2 (Cox2; Ptgs2), and the EP2 prostaglandin...Full Text Available

2000-08-29

222

First Outbreak of Multidrug-Resistant Klebsiella pneumoniae Producing both SHV-12-Type Extended-Spectrum ?-Lactamase and DHA-1-Type AmpC ?-Lactamase at a Korean Hospital

CTX-M-type extended-spectrum b2;-lactamases (ESBLs) have become increasingly common worldwide, with the notable exception of the United States, where TEM- and SHV-type ESBLs have appeared to predominate....Full Text Available

2007-11-01

223

Extended Spectrum ?-Lactamases among Gram-negative bacteria of nosocomial origin from an Intensive Care Unit of a tertiary health facility in Tanzania

PurposeCoexistence of different classes of b2;-lactamases in a single bacterial isolate may pose diagnostic and therapeutic challenges. We investigated a spread of Klebsiella...Full Text Available

2008-02-29

224

Evolution of a cluster of innate immune genes (?-defensins) along the ancestral lines of chicken and zebra finch

BackgroundResistance to third generation cephalosporins due to acquisition and expression of extended spectrum b2;-lactamase (ESBL) enzymes among Gram-negative bacteria is...Full Text Available

225

Enzymic Synthesis of Indole-3-Acetyl-1-O-?-d-Glucose ¹

BackgroundAvian b2;-defensins (AvBDs) represent a group of innate immune genes with broad antimicrobial activity. Within the chicken genome, previous work identified 14 AvBDs...Full Text Available

226

Effects of exogenous female sex-steroid hormones on lymphocyte ?₂-adrenoceptors in normal females

The first enzyme-catalyzed reaction leading from indole-3-acetic acid (IAA) to the myo-inositol esters of IAA is the synthesis of indole-3-acetyl-1-O-b2;-d-glucose...Full Text Available

1988-12-01

227

Comparison of Human Serum Dopamine-?-Hydroxylase Levels by Radioimmunoassay and Enzymatic Assay

We have previously shown that lymphocyte b2;₂-adrenoceptors (AR) are under cyclical control of sex-steroid hormones with greater receptor density during the luteal phase of the menstrual...Full Text Available

1996-05-01

228

Chromosome-Encoded Ambler Class A ?-Lactamase of Kluyvera georgiana, a Probable Progenitor of a Subgroup of CTX-M Extended-Spectrum ?-Lactamases

Human serum dopamine-b2;-hydroxylase (3,4-dihydroxyphenylethylamine, ascorbate:oxygen oxidoreductase, EC 1.14.17.1) has been measured in a normal adult population by both enzymatic assay and by...Full Text Available

1974-03-01

229

Chromosomal Integration of the Extended-Spectrum ?-Lactamase Gene bla_CTX-M-15 in Salmonella enterica Serotype Concord Isolates from Internationally Adopted Children?

A chromosome-encoded b2;-lactamase gene, cloned and expressed in Escherichia coli from Kluyvera georgiana reference strain CUETM 4246-74 (DSM 9408), encoded the...Full Text Available

2002-12-01

230

Besarhanamides A and B from the marine cyanobacterium Lyngbya majuscula

We report the emergence of Salmonella enterica isolates of serotype Concord (and its monophasic variant 6,7:l,v:-) producing the extended-spectrum b2;-lactamases (ESBLs) SHV-12...Full Text Available

2009-05-01

231

British Library Electronic Table of Contents (United Kingdom)

Besarhanamides A (1) and B (2) are fatty acid amides purified from the marine cyanobacterium, Lyngbya majuscula, collected from Pulau Hantu, Singapore. The structure determination of these secondary metabolites was carried out using extensive 2D NMR spectral data as well as chemical manipulations including the Marfey's method. In addition, besarhanamide A exhibited moderate toxicity with LD50 at 13mM in the brine shrimp toxicity bioassay.

2008-01-01

232

Association between Handling of Pet Treats and Infection with Salmonella enterica Serotype Newport Expressing the AmpC ?-Lactamase, CMY-2

A New Metal-Binding Site for Yeast Phosphoglycerate Kinase as Determined by the Use of a Metal-ATP Analog

Resistance to the extended-spectrum cephalosporins can occur in Salmonella species via the production of extended-spectrum and AmpC b2;-lactamases. We describe human infections...Full Text Available

2003-10-01

233

In vitro and in vivo analysis of pegulated Avidin

Suicide substrate b2;, γ-bidentate Rh(III)ATP (RhATP) was used to map the metal ion-binding site in yeast phosphoglycerate kinase (PGK). Cleavage of the RhATP-inactivated enzyme with...Full Text Available

1997-02-01

234

Summing Radiative Corrections to the Effective Potential

Full text: In 1995, we demonstrated the use of pretargetting three steps method and biotinylated tetracycline using radiolabelled {sup 99m}Tc-DTPA-biocytinamide for the detection of tumour cells in (C57B1/6 x BALB/C) F1 mice with E-3 thymoma. The three steps were (1) IP injection of biotinylated-tetracycline conjugate (1:1) ratio, (2) 96 hours later Avidin/Streptavidin was injected, and (3) 24 hours after (2), {sup 99m}Tc-biocytinamide -cDTPA was injected. Mice were sacrificed 16/24 h after (3) by cervical dislocation. Biodistribution of radioactivity tumour to blood, liver, bone were T:B1= 15.0, T:Li= 5.08, T:Bo=15.0. The percentage of injected dose per g was T= 3.15% and B1= 0.21%. To prolong circulation of Avidin and therefore its uptake into tumour, Avidin was covalently bound to polyethylene-glycol (PEG20 KD) at the molar ratio of PEG:Avidin 100:1 and ...

1997-09-01

235

Study of duality in the transition region at Jlab

When one uses the Coleman-Weinberg renormalization condition, the effective potential $V$ in the massless $\\phi_4^4$ theory with O(N) symmetry is completely determined by the renormalization group functions. It has been shown how the $(p+1)$ order renormalization group function fix the N$^{p}$LL order contribution to $V$. We discuss here how, in addition to fixing the N$^{p}$LL contribution to $V$, the $(p+1)$ order renormalization group functions also can be used to determine portions of the N$^{p+n}$LL contributions to $V$. When these contributions are summed to all orders, the singularity structure of \\mcv is altered. An alternate approach to fixing \\mcv in terms of the renormalization group functions is shown to eliminate dependence on the background field if spontaneous symmetry breaking occurs.

2010-01-01

236

Absolute cross sections for near-threshold electron-impact excitation of the 3s"2"1S#->#3s3p"1P and 3s"2"1S#->#3s3p"3P transitions in Si"2"+

Inclusive double spin asymmetries obtained by scattering polarized electrons off polarized protons and deuterons have been analyzed to address the issue of quark-hadron duality in the polarized spin structure functions g^p_1 and g^d_1. A polarized electron beam, solid polarized NH_3 and ND_3 targets and the CEBAF Large Acceptance Spectrometer (CLAS) in Hall B were used to collect the data. The resulting g^p_1 and g^d_1 were averaged over the nucleon resonance energy region (M < W < 2.00 GeV), and three lowest lying resonances individually for tests of global and local duality.

2007-01-01

237

Absolute total cross sections for electron-impact excitation of the 3s"2"1S#->#3s3p"3P and 3s"2"1S#->#3s3p"1P transitions in Si"2"+ were measured using the merged electron-ion beams energy-loss technique. The results are compared to R-matrix close-coupling theory, which predicts a strong resonance enhancement of the cross section near the threshold for excitation of the "3P state and this is confirmed by the experiments. The observed disagreement between theory and experiment for the dipole excitation is suggested to be due to resonance interference. copyright 1997 The American Physical Society.

238

ap11137i.b

Inherited sterility progeny gamma irradiated male Spiny Bollworm Earias Insulana Boisd

NaiaJ MajaL 8"3 LalaM KamaN JanaP 1# JaoaQ "# !" ##02 IaqaR ';?9#.%) 1"30 HaraS !"*!'$ 12#0!"# GasaT 23 1 FataU "# 1 EauaW 1"3 DavaX CawaX 133 ! ...

239

Hyperfine anomaly measurements in francium isotopes and the radial distribution of neutrons

The present work studies the fecundity, egg batching and mating of normal females of Earias Insulana Boisd. crossed with males irradiated as 24 h adult moths with two doses (80 and 100 Gy.) of gamma radiation. The male progeny were out bred or inbred with untreated individuals for two successive generations F_1and F_2 and their progeny was observed for any inherited deleterious effects on reproduction. The female fecundity and egg hatch were significantly reduced among P1,F1 and F2 generations by increasing the dosages applied to P_1 males as compared with the untreated control. The percentage of mating of P_1 females was significantly reduced at the two doses as compared to the untreated control. The average number of spermatophores per mated female was reduced among P_1,F_1 and F_2 generations when parental males were ...

2003-01-01

240

Evaluation of chitosan/beta-tricalcium phosphate microspheres as a constituent to PMMA cement.

We have performed precision measurements in a magneto-optical trap of the 7P1/2 hyperfine structure of the isotopes 209-210Fr. The ratio of these hyperfine constants to the previously measured 7S1/2 ground state values reveals a significant hyperfine anomaly. This anomaly results from the different radial dependence of the electron density in the two atomic levels. The measurements are sensitive to changes in the radial distribution of the neutron magnetism.

1999-09-01

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241

Charmonium with three flavors of synamical quarks

Two methods, a traditional emulsion technique and a high voltage electrostatically modified encapsulation system, were used to fabricate degradable chitosan/beta -tricalcium phosphate (beta-TCP) microspheres. The two distinct kinds of microspheres both exhibited good sphericity and the beta-TCP was trapped well inside the chitosan gel. The microspheres prepared by high voltage electrostatic system exhibited a rougher outer surface and narrower size distribution. These microspheres were then used as an added constituent to commercially available PMMA bone cement. Four modified cement composites that were prepared with different composition ratios of the two kinds of chitosan/beta-TCP microspheres that were made from emulsion technique (C1P1 and C2P1) and from a process by a high voltage electrostatic system (EC1P1 and ...

2005-06-01

242

Basis for the Specificity and Activation of the Serpin Protein Z-dependent Proteinase Inhibitor (ZPI) as an Inhibitor of Membrane-associated Factor Xa*

We present a calculation of the charmonium spectrum with three flavors of dynamical staggered quarks from gauge configurations that were generated by the MILC collaboration. We use the Fermilab action for the valence charm quarks. Our calculation of the spin-averaged 1P-1S and 2S-1S splittings yields a determination of the strong coupling, with {alpha}{sub {ovr MS}}(M{sub Z}) = 0.119(4).

2003-12-23

243

Enhanced corrosion resistance of Fe_4_0Ni_3_8Mo_4B_1_8 and Nd_1_5Fe_7_7B_8 by laser glazing

The serpin ZPI is a protein Z (PZ)-dependent specific inhibitor of membrane-associated factor Xa (fXa) despite having an unfavorable P1 Tyr. PZ accelerates the inhibition reaction ∼2000-fold...Full Text Available

2010-06-25

244

Effect of butylated hydroxytoluene pretreatment on the excretion, tissue distribution and DNA binding of (/sup 14/C)aflatoxin B1 in the rat

Laser glazing, using a KrF excimer laser (> = 248 nm, >a = 22 ns), has been used to improve the corrosion resistance properties of crystallized Fe_4_0Ni_3_8Mo_4B_1_8 (Metglas 2826 MB) and the permanent magnet material Nd_1_5Fe_7_7B_8. The formation of an amorphous layer was confirmed by conversion-electron Mossbauer Spectroscopy (CEMS), and the thickness of the amorphous layer was determined from the attenuation of the x-rays diffracted from the underlying crystalline material. The variation with laser fluence of the amorphous layer thickness on the Metglas were measured. The corrosion properties of the original, crystalline and laser glazed Metglas were measured potentiodynamically in acid electrolyte. Similar voltametric characteristics were obtained for the laser glazed surface and original Metglas, both showing a lower current in the passive region than the crystalline material. Laser glazing of the Nd_1_5Fe_7_7B_8 also produced a ...

1988-09-21

245

Antifungal thiopeptide cyclothiazomycin B1 exhibits growth inhibition accompanying morphological changes via binding to fungal cell wall chitin

The effect of butylated hydroxytoluene (BHT) pretreatment (0.5% in the diet for 10 days) on the excretion, tissue distribution and DNA binding of orally administered (/sup 14/C)aflatoxin B1 (AFB1) was determined in male Fischer F344 rats. The amount of radioactivity excreted in the urine and feces by 24 hr was higher in BHT-treated rats than in controls. Treatment with BHT enhanced the excretion of water-soluble metabolites in the urine and in the large intestines plus feces at the earlier sampling times. The amount of radioactivity bound to hepatic nuclear DNA was six times less in the BHT-pretreated rats than in controls 6 hr after administration of the isotope. The half-lives of (/sup 14/C)DNA in the rat liver were 30 and 46 hr for control and BHT-pretreated rats, respectively. These results indicate that BHT pretreatment may protect the animal from the carcinogenic effects of AFB1 by enhancing the detoxification and excretion of the ...

1985-06-01

246

British Library Electronic Table of Contents (United Kingdom)

Cyclothiazomycin B1 (CTB1) is an antifungal cyclic thiopeptide isolated from the culture broth of Streptomyces sp. HA 125-40. CTB1 inhibited the growth of several filamentous fungi including plant pathogens along with swelling of hyphae and spores. The antifungal activity of CTB1 was weakened by hyperosmotic conditions, and hyphae treated with CTB1 burst under hypoosmotic conditions, indicating increased cell wall fragility. CTB1-sensitive fungal species contain high levels of cell wall chitin and/or chitosan. Unlike nikkomycin Z, a competitive inhibitor of chitin synthase (CHS), CTB1 did not inhibit CHS activity. Although CTB1 inhibited CHS biosynthesis, the same result was also obtained with a non-specific proteins inhibitor, cycloheximide, which did not reduce cell wall rigidity. These ...

2011-01-01

247

String thermal tachyons as multiparticle instabilities

Induction of hepatocellular carcinoma in nonhuman primates by chemical carcinogens

The bosonic string on R"2"5xS"1 has a series of states turning tachyonic at radii implying T=IT_H. We employ the B picture to examine these thermal states in the one-loop free energy and find them in various combinations, factorizing towards rational points on the real line boundary of the fundamental domain B: (-1/2=# 0). These thermal tachyons are interpreted as signaling Hagedorn instabilities against the production of an l-highly-excited-identical-strings state, which gives a relation between the one-loop partition function and l-point functions. (orig.).

248

A neighborhood condition on all fractional $[a,b]$-factors

Several compounds were evaluated in nonhuman primates for their potential to induce neoplasms, especially hepatocellular carcinoma (HCC). The compounds can be classified into three groups: food contaminants, model rodent carcinogens, and nitrosamines. All three compounds in the food contaminants group, namely, aflatoxin B1, sterigmatocystin, and methylazoxymethanol acetate, induced HCC. None of the model rodent carcinogens tested consistently induced HCC in rhesus and cynomolgus monkeys. Three of four nitrosamines evaluated induced HCC in rhesus and cynomolgus monkeys. One nitrosamine, diethylnitrosamine, is a predictable and potent inducer of HCC and is useful for establishment of a nonhuman primate model for numerous oncologic studies.

1989-01-01

249

Spectroscopic properties of Er"3"+ ions in cadmium and alkali cadmium borosulphate glasses

In this note, we derive from Anstee's fractional $(g,f)$-factor theorem a similar characterization for the property of all fractional $(g,f)$-factors. Let $ab-1)^2+4b)$ and every pair of non-adjacent vertices has cardinality of the neighborhood union at least $bn/(a + b)$. This lower bounds are sharp.

2011-01-01

250

Microstructural development inside the stress induced martensite variant in a Ti-Ni-Nb shape memory alloy

Spectroscopic properties of Er"3"+ : CBS (CdSO_4 + B_2O_3 and R_2SO_4 + CdSO_4 + B_2O_3, R_2SO_4 = Li_2SO_4.H_2O, Na_2SO_4, K_2SO_4 and Gd_2(SO_4)_3.8H_2O) glasses are reported. The assigned energy level data of Er"3"+(4f"1"1) in these glasses are analysed in terms of a parametrized model Hamiltonian. The standard deviations of the data fits are between 39 and 47 cm"-"1 so that the energy level schemes of the Er"3"+(4f"1"1) ions in borosulphate (CBS) glasses are reasonably well reproduced. Radiative properties for the fluorescent levels of Er"3"+ : CBS glasses are determined by using the Judd-Ofelt theory. The potential laser transitions are identified with the help of predicted radiative properties which are compared and discussed with similar results. (author).

1997-01-01

251

Electrical breakdown at low pressure in the presence of a weak magnetic field

The microstructural development inside the stress induced martensite (SIM) variants in Ti-Ni-Nb alloy with various degrees of deformation have been revealed by electron microscopic observations. The orientation relationship between the SIM and the parent phase has been found: [1{bar 1}0]{sub M}{parallel}[11{bar 1}]{sub B2}, (001){sub M} 5{degree} away from (101){sub B2}. The lattice invariant shear of the SIM variants at the slightly deformed stage is dominantly (11{bar 1}) Type I twin. Besides the ordinary slip, the adjustment and development of the internal secondary twinning from (11{bar 1}) Type I twin to {l_angle}011{r_angle} Type II/ or (011) Type I twin, (001)compound twin and (111) Type I twin happen concurrently or in combination inside the SIM variants with the further deformation. The corresponding deformation mechanisms include stress induced reorientation of SIM substructural bands by the ...

2000-04-03

252

Crystal electric field excitations in the cerium compound CeRh_3B_2 studied by inelastic neutron scattering

Electron trapping in crossed electric and magnetic fields is an important mechanism by which electrical discharges can develop in low pressure gases. The authors report observations of discharges produced by this mechanism around a spherical anode in two space simulation chambers, namely the Space Plasma Interaction Experiment (SPIE) at the University of Maryland, and the NASA-Lewis B-2 chamber. They have identified two types of discharges in these experiments. In the B-2 chamber, the breakdown takes the form of a runaway dischage with spherical topology, limited only by the ability of the power supply to provide the current. In the SPIE chamber this type of discharge also occurs, in addition to a low current toroidal discharge which is observed at higher magnetic fields. They present measurements of both types of discharge and show how the trapping effect of the magnetic field together with secondary ...

1990-05-01

253

Two new paeciloxocins from a mangrove endophytic fungus Paecilomyces sp.

We have performed inelastic neutron scattering (INS) experiments on CeRh_3B_2 at various temperatures to obtain direct information on the crystal electric field (CEF) in this compound, which exhibits some very peculiar magnetic properties for a Ce system: it is ferromagnetic with an unusually high Curie temperature (115 K), which contrasts with a strongly reduced and anisotropic magnetization (0.4 #mu#_B/fu within the c-plane of the hexagonal structure). Measurements with high incident energies show only one well defined magnetic excitation around 150 meV, its exact position varying with the temperature. These results, combined with our previous data of magnetization and magnetic form factor, have permitted us to determine the CEF energy level scheme taking into account the two J multiplets of the Ce"3"+ ion. Information on the ground state (quasielastic contribution and ground state moment) has also been obtained by experiments at low incident ...

2007-12-19

254

British Library Electronic Table of Contents (United Kingdom)

Paeciloxocins A and B (2-(1-hydroxy-3-methylbutyl)- and 2-(1-acetoxy-3-methylbutyl)- 11-hydroxy-9-methyl-1-methoxy-5H,7H-dibenzo[b,g]-1,5-dioxocin-5-ones), viz., two new metabolites, were isolated from the mangrove fungus Paecilomyces sp. collected from the Taiwan Strait. Their structures were elucidated by spectral methods. Paeciloxocin A exhibited strong cytotoxicity against the hepG2 cell line.

2010-01-01

255

PDS_VERSION_ID = PDS3 FILE_NAME = "M1102254.IMQ" RECORD_TYPE ...

Simulation of dopant diffusion and activation during flash lamp annealing

UUv/4sQ d92aa%bvBR 6C7*?+'dI 1Yy! bd*O NdmD $t6b ,2Bw P,. ...... a] ULtd *w rD*M>93y eLeh "l;BdDCd u$g4rA&[` 3zD# a%robOT 9y[1 "$ngz f&6|D&" /(KUH() fG$f ...

256

Assessment of the PIUS physics and thermal-hydraulic experimental data bases

A set of advanced models implemented into the simulator Sentaurus Process was applied to simulate ultra shallow junction formation by flash lamp annealing (FLA). The full path transient enhanced diffusion model includes equations for small interstitial clusters (I_2, I_3, I_4), #left brace#3 1 1#right brace# defects and dislocation loops. A dopant-point defect clustering model is used for dopant activation simulation. Several cluster types are considered: B_2, B_2I, B_2I_2, B_3I, B_3I_2, B_3I_3 for boron and As_2, As_2V, As_3, As_3V, As_4, As_4V for arsenic. Different point defect and dopant-point defect pair charge states are taken into account to obtain accurate results in the high doping level region. The flux expressions in the three-phase segregation model include a dependence on the doping level and point defect supersaturation. The FLA process was ...

2008-12-05

257

A technique for determining the spatial and temporal distributions of surface fluxes of heat and moisture over the Southern Great Plains Cloud and Radiation Testbed

The PIUS reactor utilizes simplified, inherent, passive, or other innovative means to accomplish safety functions. Accordingly, the PIUS reactor is subject to the requirements of 10CFR52.47(b)(2)(i)(A). This regulation requires that the applicant adequately demonstrate the performance of each safety feature, interdependent effects among the safety features, and a sufficient data base on the safety features of the design to assess the analytical tools used for safety analysis. Los Alamos has assessed the quality and completeness of the existing and planned data bases used by Asea Brown Boveri to validate its safety analysis codes and other relevant data bases. Only a limited data base of separate effect and integral tests exist at present. This data base is not adequate to fulfill the requirements of 10CFR52.47(b)(2)(i)(A). Asea Brown Boveri has stated that it plans to conduct more separate effect and ...

1993-12-31

258

Synthesis, crystallographic data, solubility and electrokinetic properties of copper-, nickel- and cobalt-uranylphosphate

Land surface parameterization schemes such as the Simple Biosphere Model (SiB2) have found considerable use in climate simulation models, where they provide lower boundary conditions in the form of surface sensible and latent heat fluxes. A methodology is described to apply models of this type at high resolution, using data from the Department of Energy{close_quote}s Cloud and Radiation Testbed in Oklahoma and Kansas, to determine the spatial variations of heat fluxes over the domain and to determine area-weighted flux averages for use in single-column model studies. Data from a dense array of meteorological instruments are interpolated to provide the wind, temperature, vapor pressure, radiation, and precipitation values needed by SiB2. The state of the vegetation is characterized through the use of the normalized difference vegetation index determined from satellites. The performance of the ...

1998-03-01

259

Synthesis, crystallographic data, solubility and electrokinetic properties of copper-, nickel- and cobalt-uranylphosphate

A discussion is given concerning the transformation in acid medium of curite into copper-, nickel- and cobalt-uranylphosphate. From chemical, differential thermal and thermogravimetric analyses, the crystal-chemical formula are calculated as: Cu(UO/sub 2//PO/sub 4/)/sub 2/.8H/sub 2/O, Ni(UO/sub 2//PO/sub 4/)/sub 2/.7H/sub 2/O and Co(UO/sub 2//PO/sub 4/)/sub 2/.7H/sub 2/O. The two last compounds crystallize in the triclinic system with space group P1 or P1(overscore) and the first one crystallizes in the tetragonal system with space group P4/nmm. The cell parameters are calculated. From solubility data, the solubility products are computed as 10sup(-12.8), 10sup(-9.5) and 10sup(-9.9) for the copper-, nickel- and colbalt-compound respectively. The electrokinetic properties of the three species are closely similar to those of natural meta-torbernite: the zeta-potential is negative and the point of zero ...

1981-01-01

260

Line shapes for some specific transitions in Hydrogenic, Lithium-like, and Helium-like ions

A discussion is given concerning the transformation in acid medium of curite into copper-, nickel- and cobalt-uranylphosphate. From chemical, differentiel thermal and thermogravimetric analyses, the crystal-chemical formula are calculated as: Cu(UO_2/PO_4)_2.8H_2O, Ni(UO_2/PO_4)_2.7H_2O and Co(UO_2/PO_4)_2.7H_2O. The two last compounds crystallize in the triclinic system with space group P1 or P1(overscore) and the first one crystallizes in the tetragonal system with space group P4/nmm. The cell parameters are calculated. From solubility data, the solubility products are computed as 10sup(-12.8), 10sup(-9.5) and 10sup(-9.9) for the copper-, nickel- and colbalt-compound respectively. The electrokinetic properties of the three species are closely similar to those of natural meta-torbernite: the zeta-potential is negative and the point of zero charge be reached cannot in the pH-range 2 to 9.

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

261

Electron-impact excitation of multiply-charged ions using energy loss in merged beams: e+Si"3"+(3s"2S_1_/_2)#->#e+Si"3"+(3p"2P_1_/_2_,_3_/_2)

A set of computer codes have been developed to produce spectral line shapes of highly stripped ions for a number of transitions in Hydrogenic, Helium-like and Lithium-like species. The choice of the transitions has been dictated largely by the laser compression experiments. The transitions of Hydrogenic species are: Lyman ..cap alpha..; Lyman ..beta..; Lyman ..gamma..; Lyman delta; Balmer ..cap alpha..; and Balmer ..beta... The transitions of Helium-like species are: 1s/sup 2/(/sup 1/S/sub 0/)-1s2p(/sup 1/P); 1s/sup 2/(/sup 1/S/sub 0/)-1s3p(/sup 1/P); 1s/sup 2/(/sup 1/S/sub 0/)-1s4p(/sup 1/P) and the associated dipole-forbidden components. The transitions of Lithium-like species are the entire n = 2 to n = 3 and n = 4 complexes.

1980-12-29

262

Conceptual fusion power monitor based on the "1"6O(n,p)"1"6N reaction

For the first time absolute total cross sections for electron-impact excitation of a multiply-charged ion have been measured using an electron-energy-loss technique. Measurements were made near threshold for the process e + Si"3"+(3s"2S_1_/_2) #-># e+Si"3"+(3p"2P_1_/_2_,_3_/_2)-8.88 eV. The 10"-"1"5 cm"2 measured cross section agrees with results of 7-state close coupling calculations to better than the #+-#20% (90% CL) total uncertainty of the measurements. Convoluting the theoretical curve with a Gaussian energy distribution indicates an energy width of 0.15 < or approx. #DELTA#E < or approx. 0.20 eV. (orig.).

263

Activation cross sections for reactions induced by 14 MeV neutrons on natural ruthenium

The feasibility of developing a fusion power monitor based on a fluid activation detector is considered here. The activation fluid may be either a liquid or a gas and its composition can be selected from a number of candidate materials to provide desired activation and decay characterisitcs. Performance calculations indicate that ordinary water would be a nearly ideal activation fluid. The "1"6O(n,p)"1"6N reaction has a threshold at about 10 MeV and a cross section energy dependence giving it a predominant response for unmoderated D-T fusion neutrons. Adequate activation can be obtained at moderate flow rates for remote counting away from the high radiation area of the reactor. The 7.16 sec half-life of "1"6N is ideal for remote counting with subsequent decay in a small hold-up tank to eliminate activity build-up in the recycled water.

1981-07-01

264

``Q-deformation and energy deficit in liquid helium phonon spectrum``

Cross sections for (n,2n) (n,p) (n,#alpha#), and (n,d*)"1 reactions have been measured on ruthenium isotopes at the neutron energies of 13.5 to 14.8 MeV using the activation technique in combination with high-resolution gamma-ray spectroscopy. Data are reported for the following reactions: "1"0"4Ru(n,2n)"1"0"3Ru, "9"8Ru(n,2n)"9"7Ru, "9"6Ru(n,2n)"9"5Ru, "9"6Ru(n,p)"9"6Tc"g, "9"6Ru(n,p)"9"6Tc"m, "1"0"4Ru(n,p)"1"0"4Tc, "1"0"2Ru(n,p)"1"0"2Tc"m, "1"0"4Ru(n,#alpha#)"1"0"1Mo, "1"0"2Ru(n,#alpha#)"9"9Mo, "9"6Ru(n,#alpha#)"9"3Mo"m, and "9"6Ru(n,d*)"9"5Tc"m. Results were discussed and compared with the previous works.

2007-11-01

265

On the mechanism of the nonmonotonic relaxation processes in the metallic melts

The instability of the phonon spectrum in liquid Helium for T < 1 K is a well established experimental fact. We discuss the role of q-deformation as a possible mechanism to supply the energy deficit that forbidden one-phonon decay into two phonons when the constant {gamma} in the phonon anomalous dispersion relation ({omega}{sup ph} = c{sub 0} p(1 - {gamma}p{sup 2})) is positive, through the analysis of three-phonon processes in a q-phonons gas. (author). 19 refs.

1996-09-01

266

Investigations of electronic transitions and photodissociation of the bromine molecule

The numerical analysis of the experimental data on viscosity change by time in the period after fast heating and crystal-liquid phase transition for the copper nonequilibrium melts and the Fe_7_0Cr_1_0P_1_3C_7 glass-forming melt near their melting temperatures is accomplished through the method of correlation functions and the Rytov-Dimentberg criterion. The observed dependences have nonmonotonic oscillating character but they do not relate to auto-oscillations. The proposed theoretical model of the properties oscillations origination by relaxation in the nonequilibrium liquids explains them as manifestation of noise-induced transitions in the metastable area near the critical temperatures (melting, structural transitions)

2000-01-01

267

(/sup 3/He,n) reaction in the Aapprox. =100 region

The electronic transitions and photodissociation of the bromine molecule were studied in the visible-near UV continuum using dynamic simulation. The molar extinction coefficients in this study were obtained in numerical calculations. The quantum yields of the spin-orbit Br*(2 P 1/2) product at different photon frequencies were determined. Time-dependent density functional theory was used to analyze the highest five occupied and lowest five unoccupied Br2 orbitals. The transition to the 1? u state was found to be most probable in the visible-near UV absorption range.

2008-12-01

268

The available experimental data on the (/sup 3/He,n) reaction between the ground states of even-even nuclei and lowest 1/2/sup -/ levels of odd-A nuclei in the Aapprox.=100 region are analyzed in a systematic way by the DWBA. The deduced relative intensities of these two-proton transfers, and their uncertainties, are compared to the predictions of various nuclear models. In particular, the influence of the finite dimension of the configuration space available to the transferred protons, and of the blocking effect of a 2p1/2/sup -/ proton, are examined. (orig.).

1986-03-01

269

Quantitative RT-PCR Expression Analysis of Lipodepsipeptides Synthetase and Defence-related Genes in Orange Fruit in Response to Antagonist-pathogen Interaction

Twenty undergraduate students participated in an elaborative learning test to evaluate the relationship between electrical brain activity and subsequently recalled and not-recalled words. Data collected from the midline (Fz, Cz, Pz) and lateral scalp sites (F3, F4, C3, C4, P3, P4) were analysed. The difference between event-related potentials (ERPs) elicited by subsequently recalled and not-recalled words, the ERP memory effect, was evaluated for each portion (primacy, plateau and recency) of the serial-position curve (SPC). We compared peak amplitudes for the P1, N1, P2, N400, P3 and frontal positive slow wave (FPSW) components. The electrophysiological data support the hypothesis that different mechanisms underlie primacy and recency effects during free recall paradigms. There was no support for the hypothesis that an association arises between memory and the FPSW when subjects utilise elaborative learning strategies. The P2 component ...

2002-10-01

270

British Library Electronic Table of Contents (United Kingdom)

Abstract Strains of Pseudomonas syringae are effective in controlling postharvest diseases of citrus fruits, and antagonistic activity has been correlated with in vitro production of lipodepsipeptides. Additionally, biocontrol agents can induce a range of defence mechanisms of resistance in citrus tissue that result in a broad spectrum of metabolic modifications, such as systemic acquired resistance, induced systemic resistance and production of reactive oxygen species. The aim of this study was to evaluate the expression of syringomycin (syrB1) and syringopeptin (sypA) synthetase genes from P.syringae pv. syringae biocontrol strains in vitro on different culture media and in vivo on citrus fruits (Citrus sinensis cv. Tarocco) during the interaction with Penicillium digitatum by quantitati...

2011-01-01

271

Parametric upconversion of TM and Trivelpiece-Gould (TG) modes to high frequency Free Electron Laser (FEL)

BRE: Consultation on the Green Guide update

A backward wave oscillator (BWO) filled with a strongly magnetized plasma supports TM and Trivel-piece-Gould (TG) modes. At large amplitudes these modes may act as wigglers for generating millimeter waves via free electron laser instability. The nonlinear coupling between the wiggler, the beam space charge mode, and the high frequency free electron laser wave is dominated by parallel motions. In the Raman regime the growth rate of instability goes as #approx##omega#_p_b"1"/"2/#gamma#_o"9"/"4, where #omega#_p_b is the beam plasma frequency and #gamma#_o is the relativistic gamma factor.

272

Wastenet

...Content 3a LCA Methodology - Characterisation(PDF) 3a1 BRE Response - Characterisation 3b LCA Methodology - Normalisation (PDF) 3b1 BRE Response - Normalisation 3c LCA Methodology - Weighting (PDF) 3c1 Feedback - Weighting 3c2 Weightings Exercise (PDF) 4 Specification (PDF) 4a - Functional Units Spreadsheet (Excel) 4b Specification List (Excel) 5 Energy Model (PDF) 6 Whole Life perfomance 6b Response Note To Briefing Note 6 - Whole Life Performance (PDF) 7 End-of-Life and Waste models (PDF) 7a Waste routes and rates feedback (PDF) 7b Waste Disposal Routes for Industry Consultation 7c Site Wastage Rates for Industry Consultation 8 Existing LCA ...

273

Thermokinetic investigation of effects of carbon source on petroleum bacterial growth

The deformation behavior of DyCu ductile intermetallic compound under compression

The growth power-time curves of a strain of petroleum bacteria, B-2, in various kinds of cultures containing different kinds of carbon sources, glucose, n-tetradecane, n-hexadecane and n-octadecane, and different kinds of microemulsions have been determined by using a 2277 Thermal Activity Monitor. The curves showed a single peak for cultures containing a single carbon source, glucose, and two peaks for cultures containing two kinds of carbon sources, glucose and one of the n-alkanes. The first peak indicated that bacteria grew by consuming glucose and the second peak indicated that bacteria grew by consuming n-alkane. The curves were complex when the bacterium grows in a microemulsion culture. According to a kinetic equation of bacterial growth under limited conditions, the rate constants of bacterial growth were obtained. The results showed that the microemulsion culture was more appropriate to bacteria to grow on n-alkanes.

2002-02-07

274

British Library Electronic Table of Contents (United Kingdom)

In this study polycrystalline specimens of as-cast DyCu with B2 crystal structure were compressed to different strains at room temperature to test if stress-induced phase transformation and twinning occur during deformation. In these tests DyCu exhibited high ductility with plastic strain as high as 35% and ultimate compressive strength of ~790MPa. X-ray diffraction and transmission electron microscopy (TEM) showed no indications that DyCu had undergone stress-induced phase transformation or twinning. -type dislocations have been observed to play an important role for imparting the ductile behavior. TEM analyses showed the presence of second phases, Dy2O3 and DyCu2 within the DyCu. The mechanisms of ductility and impurity phase formation are discussed.

2011-01-01

275

Texture transformations in thermomechanically treated steels having increased nitrogen content and alloys

Study on the crystallization behaviour and thermal stability of glass-ceramics used as solid oxide fuel cell-sealing materials

In this study the results of mathematical simulation and experimental research of texture transition in stress assisted shear phase transformations are discussed. The orientation distribution function (ODF) calculation model to the any type crystalline lattice symmetry materials has been suggested. By crystalline lattice symmetry analysis this computer program determines necessary amount of the initial experimental data. The experimental verification supports this model well. The ODF calculation model after shear phase transformation with equal use of all possible variants of orientation relationship or with various degrees of variant selection worked out. In this study the experimental and calculating data of the direct and reversal shear transformations #alpha# <=> #gamma# in Fe-alloys and B2 <=> B19' in Ti-Ni alloys are discussed. The stress assisted shear phase transformation model and computer program to calculate ODF after ...

276

British Library Electronic Table of Contents (United Kingdom)

Glass ceramics are commonly used as sealing materials for planar solid oxide fuel cells (SOFCs). The major requirements of stack and module builders for these materials are the stability of the coefficient of thermal expansion (CTE), excellent bonding (sticking) behaviour and the absence of volatile ingredients, which can lead to changes of the material properties and the sealing ability. SCHOTT Electronic Packaging has developed special glasses and glass-ceramics for various solid oxide fuel cell designs and operating temperatures. The glass compositions are based on the system MgO-Al2O3-BaO-SiO2-B2O3. In this study the evaluation of the developed materials was done by high temperature aging tests for up to 1000h, high temperature XRD-studies and Rietveld calculations, combined with scann...

2011-01-01

277

Porous b2;-SiAlON Ceramic with Closed Packed Macropore

British Library Electronic Table of Contents (United Kingdom)

Porous ?-SiAlON ceramics are synthesized by reaction bonded method using hollow alumina spheres (HASs) as both sintering aids and pore-forming agents. Both micropores and macropores, which are constructured by SiAlON grains with different morphologies, are formed in the final SiAlON samples. The micropores are three-dimentional, and are built by equiaxial grains. While the hollow macropores, which have the similar morphology to hollow alumina sphere, are packed by elongated grains. In the sintering process, the solid dissolution process takes place, giving rise to the different alumina concentration of liquid phase, and thus resulting in the formation of two kinds of grains, the equiaxial grain and the elongated grain.

2011-01-01

278

Point-contact Andreev spectroscopy on thin Ni_2MnIn Heusler films

Online consumer communities, collaborative learning and innovation

Heusler films with L2_1 and B2 structure are deposited simultaneously on amorphous carbon films, Si(100) surfaces, and in situ cleaved InAs(110) surfaces by coevaporation of Ni and the alloy MnIn. Morphology, structure, and stoichiometry are investigated with transmission-electron microscopy, electron diffraction, and X-ray spectroscopy. The almost perfect lattice match supports highly oriented growth of Ni_2MnIn on InAs, which is proven by electron diffraction under grazing incidence. The electrical resistivity of thin films on Si show metallic behavior. At temperatures of liquid helium point-contact Andreev reflection spectroscopy is performed on films grown on Si(100) and in situ cleaved InAs(110) surfaces yielding spin polarizations comparable to the ones of Fe, Ni, Co, and permalloy (Ni_8_0Fe_2_0).

2007-09-01

279

British Library Electronic Table of Contents (United Kingdom)

Purpose - The paper aims to outline the managerial challenges faced by the organizations interested in leveraging knowledge and creative talent embedded in online customers' communities to sustain innovation in b-2-c industries. Design/methodology/approach - Through a detailed case study analysis of a leading food producer who launched an online open collaborative platform to gather users' idea for new products the paper aims to highlight the transformational effort that firms have to make in order to leverage knowledge absorption from customers in the context of innovation. Findings - The paper suggests potential strategies for conventional companies to engage consumers in knowledge (co-creation) and collaborative innovation processes, formulating some hypothesis that could support an int...

2011-01-01

280

Oak Ridge Research Reactor. Quarterly report, July, August, and September 1984

Moessbauer investigation of the magnetic anisotropy and electronic structure of a metallic glass

The ORR operated at an average power level of 29.7 MW for 85.3% of the time during this period. The reactor was shut down on fifteen occasions, nine of which were unscheduled. Reactor downtime needed for refueling and checks was normal. The reactor remained available for operation 88.3% of the time. Special tests completed during the quarter included: (1) transfer of LEU fuel elements CLE-202 and NLE-201 from core positions B-9 and B-2 to core positions C-5 and C-6 for continued operation; and (2) calculation of maximum heat flux in LEU elements CLE-201 and NLE-202 in core positions A-2 and A-8. In-service inspections included inspections of ORR decay tank, primary heat exchanger No. 4, and the 24-in. strainer.

1985-03-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

281

Microstructure characterization and tensile properties of b phase containing TiAl pancake

The temperature dependence of the average magnetization direction in an Fe_8_0B_2_0 glassy alloy (METGLAS 2605) is investigated by Moessbauer spectroscopy. Moessbauer spectra were recorded between 77 K and 363 K using a conventional constant-acceleration Moessbauer spectrometer with 10 mCi "5"7Co in Pd source. The direction of the easy magnetization is found to be strongly terperature dependent and the out-of-plane component turned to be unusually large. Comparing the magnetic moments some similarities between the electronic structure of the glassy alloy and the Fe_2B and FeB intermetallic compounds are established and discussed. (Sz.N.Z.).

282

British Library Electronic Table of Contents (United Kingdom)

The microstructure and tensile properties of Ti-44Al-6V-3Nb-0.3Y (at.%) alloy after canned forging were investigated. SEM results showed that the TiAl pancake exhibits inhomogeneous microstructure, which can be ascribed to the temperature drop and friction between billet and outer pack during forging, as well as the intrinsic anisotropy of lamellar colony. By means of TEM observation and EBSD analysis, the microstructure in the dominant area of the pancake was further characterized. This deformation area consists of 87.7% content of g grains plus some refined lamellar colonies and the rest of B2 grains. The grain size ranges between 1mm and 8.5mm. High-angle boundaries dominate the deformation microstructure, several substructures and twins are observed as well. Additionally, current forge...

2011-01-01

283

Mechanisms of Reproductive Thermotolerance in Gossypium hirsutum: The Effect of Genotype and Exogenous Calcium Application

British Library Electronic Table of Contents (United Kingdom)

Abstract Although photosynthetic thermotolerance has been investigated extensively in cotton leaves, reports on the biochemical influence of the pistil in promoting fertilization thermostability are limited. To evaluate the effect of temperature, genotype, and exogenous calcium application on fertilization and pistil biochemistry in cotton, thermosensitive (cv. ST4554 B2RF) and thermotolerant (cv. VH260) plants were grown under control (30/20-C) or high-temperature (38/20-C) conditions during flowering, and exogenous CaCl2 was applied to flowers 1-day prior to anthesis. Measured pistil parameters included fertilization efficiency; protein concentration; glutathione reductase, superoxide dismutase (SOD) and NADPH oxidase activities; and ATP and calcium levels. Exogenous calcium had no effec...

2011-01-01

284

Interaction studies between Crofer-22APU alloy and P2O5 containing barium calcium alumino-borosilicate (BCABS) sealant glass-ceramics

Hydrogen lines in the high-luminosity quasar B2 1225+31

We present the effect of P2O5 addition on barium calcium aluminum borosilicate BCABS glasses of composition (mol %) 35BaO-15CaO-5Al2O3-(37-x)SiO2-8B2O3-xP2O5 (0?x?5). The incorporation of P2O5 increased network polymerization and crystallization tendency. However, addition of P2O5 leads to the formation of Cr2O3 at the interface, saturating it in the ions of the metal. This improves glass-to-metal bonding. (author)

2010-09-01

285

G-factor of the 21/2/sup +/ isomer in /sup 203/Pb

The emission lines H#alpha#, H#beta#+[OIII], and L#alpha# have been observed in the high-redshift quasar 1225+31. The ratios of line intensities in 1225+31 are found to be L#alpha#/H#alpha#approx.0.8, H#alpha#/(H#beta#+[OIII]) approx.4, and 4

286

Feasibility investigations of growing and characterizing gallium arsenide crystals in ribbon form. Quarterly progress report 1 Jan-31 Mar 1975

The g-factor of the 21/2/sup +/ state at 1921.9 keV in /sup 203/Pb has been measured through the time differential perturbed angular distribution technique in an external magnetic field B=2.028 T. The measured g-factor g=-0.063(2) indicates a predominantly three neutron hole configuration described by the wave function 0.68vertical strokei/sup -1//sub 13/2/f/sup -2//sub 5/2/>+-0.73vertical strokei/sup -1//sub 13/2/f/sup -1//sub 5/2/p/sup -1//sub 3/2/>.

1986-12-01

287

Effect of alloying on the phase transformations and properties of a nickel alloy

The feasibility of continuous production of gallium arsenide ribbon single crystals, by passage of a molten zone through boron-oxide encapsulated GaAs feedstock, is being investigated. Polycrystalline GaAs ribbons have been grown in graphite boats by passage of a wide zone through B2O3-encapsulated feed-stock, confined by a quartz cover plate. Failure to remove the encapsulant above its glass transition temperature, however, resulted in cracking of the ribbons on cooling to room temperature. In order to study the crucial zone melting step in isolation from the encapsulation steps of the continuous process, a constrained-zone melting apparatus has been constructed in which the boron oxide serves only as a sealant to suppress arsenic vaporization. Large grained polycrystalline samples have been produced with this apparatus.

288

Development of Point Arguello field, offshore California

The phase transformations and properties of a precipitation-hardened Ni-Cr-based alloy are investigated as a function of C, B, Nb, and Cr contents. It is found that the primary role of Nb consists in the formation of an independent phase, delta-Ni3Nb, a part of a gamma/gamma-prime-delta eutectoid (for high C and B concentrations) and in stimulating the gamma-sigma reaction consecutively with the gamma double prime-delta reaction (for low C and B concentrations). In both cases, the long-term strength characteristics of the Nb-alloyed system are relatively low. The substitution of boron for carbon contributes to a reduction in the number of nucleation sites for topologically close-packed phases and to the formation of more stable (with respect to excess compounds) M3B2 and MB2 borides. The high-boron material exhibits better properties and phase stability under mechanical and thermal loading. 13 references.

1986-07-01

289

Combining climate with other influential factors for modelling the impact of climate change on species distribution

Development drilling from Chevron-operated Platform Hermosa, located on OCS-P 0316 of the Point Arguello field, began on January 30, 1987. To date, seven development wells have been drilled in to the northwest-southeast-trending, doubly plunging anticlinal structure. The results from drilling have confirmed the presence of intense folding and fracturing in the targeted Monterey Formation. Over 700 ft of conventional core were recovered from the B-2 well in the lower Sisquoc and Monterey Formations. Analysis of the core material has yielded important information on lithologic variations and fracture patterns in the productive Monterey Formation. Initial results of core studies, DST data, and wireline studies indicate a correlation between rock type and fracturing. Fracture trends and directional permeability suggested by drill-stem testing may affect future drilling patterns in the field.

1988-03-01

290

British Library Electronic Table of Contents (United Kingdom)

We tested two approaches to forecast species distributions while balancing the impact of climate change against the inertia promoted by other influential factors that have been forecast as not changing. Given that mountain species are presumed to be more at risk due to climate warming, we selected an amphibian, a reptile, a bird, and a mammal species present in the Spanish mountains, to model their distributional response to climate change during this century. The climatic forecasts were made according to the general circulation models CGCM2 and ECHAM4 and to the A2 and B2 emission scenarios. We modelled the response of the species to spatial, topographic, human, and climatic variables separately. In our first approach, we compared each of these single-factor models using the Akaike Inform...

2011-01-01

291

Catalytic effect of oxides and sulfides of metallic minerals on hydrogenation of Kansk-Achinsk brown coal

A strategy for implementing non-perturbative renormalisation of heavy-light four-quark operators in the static approximation

Discusses results of investigations into catalytic properties of various minerals during hydrogenation of Kansk-Achinsk brown coal with a view to replacing synthetic compositions based on molybdenum. Describes tests and equipment used in hydrogenation of grade B-2 Borodinsk deposit coal in tetralin (hydrogen donor). Various by-products of metallurgical processes and compounds separated from tailings containing mainly iron and sulfur and other metals were used as catalysts. States that: minerals containing iron compounds in the form of pyrites, hematites and magnetites exhibit catalytic properties when used in the hydrogenation of brown coal; pyritic catalysts enrich liquid products with hydrogen while sulfur and nitrogen content remains the same; the yield of malthenes with pyritic catalysts is no lower than with alumocobaltmolybdenum catalysts. 18 refs.

1988-05-01

292

5.6-nm p"+/n junction formation for sub-0.05-#mu#m PMOSFETs by using low-energy B_1_0H_1_4 ion implantation

We discuss the renormalisation properties of the complete set of {delta}B=2 four-quark operators with the heavy quark treated in the static approximation. We elucidate the role of heavy quark symmetry and other symmetry transformations in constraining their mixing under renormalisation. By employing the Schroedinger functional, a set of non-perturbative renormalisation conditions can be defined in terms of suitable correlation functions. As a first step in a fully non-perturbative determination of the scale-dependent renormalisation factors, we evaluate these conditions in lattice perturbation theory at one loop. Thereby we verify the expected mixing patterns and determine the anomalous dimensions of the operators at NLO in the Schroedinger functional scheme. Finally, by employing twisted-mass QCD it is shown how finite subtractions arising from explicit chiral symmetry breaking can be avoided completely. (Orig.)

2006-04-15

293

Transverse and longitudinal excitation modes in interacting multispin systems

Decaborane (B_1_0H_1_4) cluster ions were implanted into n-Si(100) substrates to fabricate shallow p"+/n junctions. Implant energies of 2 keV, 5 keV, and 20 keV, equivalent to implant energies of the monomer boron ion of 174 eV, 435 eV, and 1.74 keV, respectively, were used at dosages of 1 X 10"1"2 /cm"2 and 1 X 10"1"3 /cm"2. The implanted samples were then subjected to activation annealing at 800 .deg. C, 900 .deg. C, and 1000 .deg. C for 10 s. By using secondary ion mass spectrometry (SIMS) depth profiles, we determined that the depth of the shallow junction (D_s) at a dosage of 1 X 10"1"3 /cm"2 was in the range 12 nm - 45 nm after annealing at 1000 .deg. C. D_s and transient enhanced diffusion (TED) were greatly reduced at implant energies lower than 5 keV, but thermal diffusion (TD) smoothly decreased. In particular, TED was suppressed in the p"+/n junction implanted at 2 keV and a dosage of 1 X 10"1"3 /cm"2, and the formation of only a ...

2004-06-01

294

The crystal structure of YPdSi, the isotopic compounds LnPdSi (Ln=Gd-Lu), and their structural relation to some other equiatomic compounds of the rare earth and transition metals with main group elements

Magnetic excitation in coupled multispin system is studied theoretically focusing on Cu_2Fe_2Ge_4O_1_3 and Cu_2CdB_2O_6 as typical examples of such system. These compounds consist of spin dimer and spin monomer parts and show an antiferromagnetic phase transition at low temperatures due to the spin monomer part. A multispin containing a spin dimer and spin monomers is treated as a basis unit. The multispin forms a spin multiplet and its energy levels are separated into high and low regions reflecting the characteristic energies of the dimer and monomer parts. We regard the system as interacting multispins and apply an extended Holstein-Primakoff theory by introducing bosons for each energy level of a spin multiplet. In the low-energy region, the obtained magnon dispersion and dynamical spin correlation function agree quantitatively with experimental results of inelastic neutron scattering performed in Cu_2Fe_2Ge_4O_1_3. Analyzing dynamical spin ...

2010-08-01

295

All focused ion beam fabricated MgB_2 inter-grain nanobridge dc SQUIDs

The nine title compounds were prepared from the elements by arc-melting and subsequent heat treatment in resistance and high-frequency furnaces. The crystal structure of these isotypic compounds was determined for YPdSi from single-crystal X-ray diffractometer data: Pmmn, a = 430.8(1) pm, b = 1391.2(1) pm, c = 743.1(1) pm, Z = 8, R = 0.024 for 417 structure factors and 40 variable parameters. The crystal structures of the isotypic compounds GdPdSi and ErPdSi were also refined from single-crystal data. The structure is of a new type. It consists of condensed, six-membered rings of alternating palladium and silicon atoms with Pd-Si bond distances varying between 249.6 and 258.8 pm. These two-dimensionally infinite nets are connected to each other via weak Pd-Si and Si-Si bonds with bond distances of 276.3 and 259.5 pm. The rare earth atoms are situated above and below the six-membered palladium-silicon rings in a manner as it is known for the aluminum atoms in the ...

296

The influence of target backing on ion-beam electron spectra

We have fabricated MgB_2 dc SQUIDs (superconducting quantum interference devices) containing inter-grain nanobridges as Josephson elements by a focused ion beam (FIB) etching method and measured their transport properties. The entire structure including the SQUID loop was patterned only using a FIB. The beam energy was 30 kV and the current was 0.9 nA for larger structures and 34 and 1.5 pA for the nanobridge pattern. Each bridge with a nominal width of 100 nm crossed a single grain boundary in the normal direction. The SQUID loop had a 3.1 #mu#m x 3.1 #mu#m hole with a 2 #mu#m average linewidth, corresponding to an inductance of 5.1 pH. The nanobridges had a two-step transition with an increase in the resistivity of more than a decade and a substantial decrease in the critical current density. Current-voltage characteristics showed a resistively shunted junction behavior at all temperatures below T_c, which implies that the current in the ...

2009-06-01

297

Optical properties and up-conversion of Pr"3"+ doped CdS nanoparticles in sol-gel glasses

Several different aspects of the influence of the target backing on in-beam electron spectra following compound nuclear reactions induced by accelerated ions at tandem energies irradiating backed targets are discussed in detail. This discussion is illustrated by a few typical examples, such as "1"2C"5"+ and "3"1P"1"0"+ beams at 4 MeV/u bombarding Sn(+Be), Sn(+Au), Pb(+C) backed targets. Moreover, the relative influence of electron backscattering, electron Doppler shift and Doppler broadening as well as #delta#-electron emission on the low energy electron spectra (E_e#<=#100 keV) obtained under such conditions are investigated in the frame of the available experimental data. (orig.).

298

Is the 4.742 MeV state in "8"8Sr the 1"- two-phonon state?

Silica glasses containing Pr"3"+ with and without CdS nanoparticles were prepared by sol-gel technique. The influence of CdS nanoparticles on Pr"3"+ doped glass was studied by absorption, photoluminescence and up-conversion. From the measured intensities of various absorption bands of these glasses, the Judd-Ofelt parameters ?_2, ?_4 and ?_6 have been evaluated. The radiative transition probability (A), radiative lifetime (?_R), branching ratio (?_R) and integrated emission cross-section (?_P) were calculated from excited states of "3P_1 and "3P_0 levels. The up-conversion emissions were found in the green, orange and red regions under 800 nm excitation with peaks 559, 612 and 688 nm respectively. On excitation with 370 nm also leads to similar green, orange and red regions.

2010-10-01

299

Fine structure excitation transfer between the potassium 4"2P states induced by collisions with caesium atoms

A nuclear resonance fluorescence experiment on "8"8Sr has been performed with bremsstrahlung of 6.7 MeV endpoint energy. The #gamma#-ray linear polarisation has been measured with a EUROBALL CLUSTER detector used as a Compton polarimeter. The results indicate positive parity for the J=1 state at 4.742 MeV in "8"8Sr, in contrast to the previous interpretation as a 1"- two-phonon (2"+_1 x 3"-_1) state and in conflict with the predictions of the quasiparticle-phonon model. On the basis of such calculations the 1"+ state at 3.486 MeV may be considered as the 1"+_1 one-phonon state and the very strong 1"+_1#->#0"+_1 deexcitation as proton spin-flip 2p_1_/_2#->#2p_3_/_2 transition. (orig.)

2000-01-01

300

Excitation functions and yields of the (d,p) reactions on natural molybdenum for deuteron energies less than 13 MeV

Applying diode-laser resonant fluorescence method, the cross sections for the excitation energy transfer of the collisional process K"*(4"2P_1_/_2)+Cs(6"2S_1_/_2)#reversible#K"*(4"2P_3_/_2)+Cs(6"2S_1_/_2) have been measured. The values we have obtained are #sigma#(1/2#->#3/2)=77 A"2 and #sigma#(3/2#->#1/2)=48 A"2. These results complete the sequence of data for the fine-structure mixing of the first-resonance states of alkali atoms colliding with the ground-state caesium atoms. (orig.).

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

301

Electron-impact excitation of Si"3"+(3s#->#3p) using a merged-beam electron-energy-loss technique

The excitation functions of the reactions "9"8Mo(d,p)"9"9Mo and "1"0"0Mo(d,p)"1"0"1Mo have been determined by irradiation of stacked foils with deuterons of energies less than 13 MeV and non-destructive determination of the absolute activity of the Mo radioisotopes by semiconductor #gamma#-ray spectrometry. From the excitation functions, the thick-target yields and the saturation production rates of "9"9Mo and "1"0"1Mo for deuteron energies of 13.0 MeV and 11.7 MeV have been calculated. Implications for the production of "9"9Mo for generators of sup(99m)Tc are discussed. (author).

302

Doppler-free optogalvanic spectroscopy of sup(88,86)Sr I and II

For the first time, absolute cross sections for electron-impact excitation of a multiply charged ion have been measured using an electron-energy-loss technique. Cross sections for e+Si"3"+(3s "2S_1_/_2)#->#e+Si"3"+(3p "2P_1_/_2_,_3_/_2)-8.88 eV have been measured with an accuracy of #+-#20% (at 90% confidence level) over a narrow energy range (#+-#0.6 eV) about the threshold energy with an energy resolution of 0.2 eV. Results are in good agreement with close-coupling calculations.

303

Crystallization and preliminary X-ray studies of a galactose-specific lectin from the seeds of Spatholobus parviflorus

We have measured the isotope shifts of some dipole transitions between excited states of the even strontium isotopes 88 and 86 by applying the technique of Doppler-free intermodulated optogalvanic spectrocopy to a heat-pipe discharge. We were also able to investigate the isotope shift of the Sr II resonance line at 4216.6 A optogalvanically in the mentioned pair of isotopes. Because the 5 snf"1F_3 series appear to have zero level isotope shifts for n>=6, we can give residual level isotope shifts (RLIS) of several odd-parity states of sup(88,86) Sr I. The RLIS of the 5 snp "1P_1 series show pronounced configuration mixing around n=7. (orig.).

304

British Library Electronic Table of Contents (United Kingdom)

A galactose-specific seed lectin was purified from the legume Spatholobus parviflorus and crystallized using the hanging-drop vapour-diffusion technique. Thecrystals belonged to space group P1, with unit-cell parameters a = 60.998, b=60.792, c = 78.179-, = 101.32, = 91.38, = 104.32. X-ray diffraction data were collected under cryoconditions (100-K) to a resolution of 2.04- using a MAR image-plate detector system mounted on a rotating-anode X-ray (Cu-K) generator. Molecular replacement using legume-lectin coordinates as a search model gave a tetrameric structure.

2011-01-01

305

Comparison of the channel coupling array and CRC methods for a realistic nuclear transfer-reaction model

Ab initio relativistic many-body calculation of hyperfine splitting of ^{113}Cd^+

Using a realistic three-body model, angular distributions for the "1"6O(d,p)"1"7O(1/2"+) reaction, based on the channel coupling array (CCA) theory and various forms of the coupled reaction channel (CRC) method are compared. Despite the different forms and theoretical foundations of these methods, they yield similar angular distributions, within the bound state approximations used herein. The expected breaking of time reversal inveriance in the approximated CCA theory is quite small over most of the angular range. Of all the methods used, coupling effects in the forward directions are largest for the post form of the CRC, indicating that it is the least reliable of the CRC forms for fitting data. (Auth.).

306

Development of radioimmunometric assays and kits for non-clinical applications. Proceedings of a final research coordination meeting

This work presents accurate ab initio determination of the hyperfine splitting for the ground state and few low-lying excited states of 113Cd+; important candidates for the frequency standard in the microwave region, using coupled-cluster theory (CC) in the relativistic framework. The calculated hyperfine splitting are well in agreement with recent experimental results. We have also carried out the lifetimes of the 5p2P1=2 and 5p2P3=2 states, which are in well agreement with recent experimental result (Moehring et al., PRA 73 023413, 2006). The roles of different electron correlation effects in the determination of these quantities are discussed and their contributions are presented in the CC terms.

2007-01-01

307

Study of heavy-ion reactions with the unstable Nuclei, {sup 11}Be and {sup 13}N

Immunoassays are versatile analytical techniques that had a leading role in various clinical applications, during the last four decades. The studies carried out by Rosalyn Yalow, Solomon Berson and Roger Ekins in the 1960s gave a breakthrough in the development of this novel analytical method. Sensitivity up to femtomolar concentrations, high specificity and universal application to different classes of molecular species made immunoassay a very useful tool in analytical investigation. The expertise acquired by immunochemists in producing antibodies against any antigen and the ability of radiochemists in labeling the antigens with "1"2"5I without affecting the active site are the two main factors responsible for the above development. There are concerns about the safety and health of humans due to the high-level contamination of environment by pesticides, industrial compounds and metals, anabolic steroids in milk and meat products, and presence of mycotoxins in food and feed ...

2004-12-06

308

Investigations into the corrosion resistance of copper aluminium alloys. Effect of phosphorus as corrosion resistant third alloying element in the ternary system CuAl20P1

Heavy-ion reaction with unstable nuclei, {sup 13}N and {sup 11}Be, {sup 13}N+{sup 12}C and {sup 11}Be+{sup 12}C-{sup 10}Be+{sup 13}C were analyzed by a coupled-reaction-channel (CRC) method and formation of valence nucleon molecular orbital was studied by numerical analysing calculation. In this report, 1P1/2 (the ground state of {sup 13}N and {sup 13}C), 2s1/2 (the ground state of {sup 11}Be), 1d5/2 and 1d3/2 orbital were studied as one particle state of valance nucleon in {sup 13}N, {sup 13}C and {sup 11}Be. Moreover, d3/2 state, comparatively higher excited state, was contained into CRC calculation. The effect of this state on CRC scheme was proved very large. We developed new program code to obtain the numerical stable solution. It is necessary to about 200 MB (CRC equation) for {sup 11}Be+{sup 12}C{yields}{sup 10}Be+{sup 13}C and about 300 MB for discussion about molecular orbital. We show that the CRC calculation with the inelastic ...

1996-06-01

309

Experimental investigation of the KLL Auger spectrum of "8"8Sr from the EC-decay of "8"8Y

The effect of phosphorus on the corrosion resistance of Al-bronzes is studied in detail in this work. A literature review showed that there are a lot of things known about the microstructure and the mechanical properties of Al-bronzes. In spite of their corrosion resistance the corrosion properties and the structure of the protective oxide films of Al-bronzes were seldom a matter of interest. Systematic studies of the influence of different alloying elements on the oxide film and the corrosion properties are rare. Therefore, it is not possible to predict the corrosion resistance of Al-bronzes, made by alloying particular elements. The high corrosion resistance of the new alloy CuAl_2_0P_1 was the reason to investigate the influence of phosphorus on the corrosion properties of Al-bronzes in more detail. A systematic study of the microstructure and the corrosion properties of Cu, CuP_x, CuAl_2_0 and CuAl_2_0P_x offers an insight into the effect ...

310

Characterization of VPO ammoxidation catalysts by in situ methods

According to the calculations, intensity of the KL_1L_2("3P_0) Auger transition should drastically increase with increasing atomic number Z due to the relativistic effects. However, this behavior was experimentally proved only for very few elements. A lack of enough precise experimental data in the atomic number region Z<45 does not enable one to distinguish between relativistic and non-relativistic approaches in this region. Thus for Z=38 the KL_1L_2("3P_0/"1P_1) intensity ratio was determined with relative uncertainty of 63 % in the only measurement with external excitation. Here we present results of our investigation of the KLL Auger electron spectrum of "8"8Sr generated in the EC decay of "8"8Y (T_1_/_2= 106.6 d). Electron spectra were measured with the 11 eV instrumental resolution using a combined electrostatic spectrometer. The present value of the KL_2L_3("1D_2) absolute transition energy in Sr is higher by 7.4 eV (i.e. more than ...

2007-06-04

311

The phase shifts leading to the broadening and shift of spectral lines

In-situ methods are well known as powerful tools in studying catalyst formation processes, their solid state properties under working conditions and the interaction with the feed, intermediates and products to reveal reaction mechanisms. This paper gives a short overview on results of intense studies using in-situ techniques to reveal VPO catalyst generation processes, interaction of educts, intermediates and products with VPO catalyst surfaces and mechanistic insights. Catalytic data of the ammoxidation of toluene on different VPOs complete these findings. The precursor-catalyst transformation processes were preferently investigated by in-situ XRD, in-situ Raman and in-situ ESR spectroscopy. The interaction of aromatic molecules and intermediates, resp., and VPO solid surfaces was followed by in-situ ESR and in-situ FTIR spectroscopy. Mechanistic information was mainly obtained using in-situ FTIR spectroscopy and the temporal-analysis-of-products (TAP) technique. Catalytic studies ...

1998-12-31

312

The magnetoresonance operation of microwiggler on the piezoelectrics with a strong magnetic guide field

The classical theory of collisional broadening and shift parameters (?, ?) of an isolated spectral line was used to obtain simple analytical formulas for calculating both ? and ?. These formulas were obtained on the assumption that the short range interaction is effective only in the broadening while the long range is effective in the shift of the spectral line. These parameters ? and ? depend on the limiting phase shifts responsible for broadening ?b and shift ??. It was found that the values of ?b and ?? are not equal to each other as was proposed by Weisskopf ?b=??=1. The maximum and average values of ?b (?bmax, ?bav) and ?? (??max, ??av) were obtained by numerical evaluation, using different inverse power potentials. By introducing these parameters into the approximated formulas for ? and ? using Van der Waals and Lennard-Jones potential, it was found that the results of calculations for (? and ?) with different atomic transitions perturbed ...

2009-02-01

313

Preparation of ZnO varistors by solution nano-coating technique

We proposed that a new type of the electrostatic microwiggler with a wiggler period (0.1 mm {le}1{sub w}{le}1 mm) and the wiggler field strength (E{sub w}{le} 100 kV/m) can be produced on the surface of a PZT when a high power and high frequency ultrasonic wave travels through a PZT bar. Numerical simulations in the linear and nonlinear gain regime show that a weak microwiggler (E{sub w}100 kV/m,{lambda}{sub w}{approx}100 periods), operating in magnetoresonance with a strong guide field (B{sub o}{approx} 3.6T), can generate a millimeter and submillimeter radiations with medium electronic efficiency of few percents. It is shown that the maximum output power of the compact FEL using the wiggler system generated on the surface of the piezoelectric material may be upto a few Watts with a relatively low energy and low current electron beam (Ew {approx}100 keV and I{sub b}1 mA).

1995-12-31

314

Nanocrystallization of soft magnetic Fe-Co-Zr-Cu-B alloys

This paper introduces a new method to produce nano-composite powder for the preparation of high performance ZnO varistors. ZnO particles were coated with Bi{sub 2}O{sub 3}, Sb{sub 2}O{sub 3}, Co{sub 2}O{sub 3}, Cr{sub 2}O{sub 3} and other additives via liquid nano-coating technique. Then the prepared powder was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), thermal gravity and differential scanning calorimetry (TG-DSC) and particle size distribution. The results showed that the ZnO composite powder is homogeneously coated and ultrafine. The densification, phase composition and microstructure of ZnO varistors was studied by linear shrinkage, X-ray diffraction (XRD) and SEM, respectively. The preliminary electrical parameters of ZnO varistors showed that the breakdown voltage V {sub b} (1 mA/cm{sup 2}) and nonlinear coefficient {alpha} is 5400 V/cm and 50, respectively, much higher than that of ...

2006-06-15

315

Interactions between organic anions on multiple transporters in Caco-2 cells.

In the present study, Fe_4_1Co_4_1 B_1_0Zr_7Cu_1 alloy has been investigated in order to evaluate its thermal stability and structure after heat treatment, as well as the impact of heat treatment on magnetic properties. X-ray diffractometry, differential scanning calorimetry, chemical composition microanalysis, transmission electron microscopy, and magnetic hysteresis loop measurement techniques were employed. The crystallization temperature of the as-quenched alloy is 490"oC (continuous heating at 5 "oC/min). The melt spun ribbon having 27 #mu#m in thickness was annealed for 1 hour at temperatures from 400 to 700 "oC. The alloy after treatment at about 550"oC underwent primary crystallization, with the average size of crystals under 20 nm. This specimen shows the coercive field of 38 A/m, as compared to about 160 A/m reported for a similar alloy (Fe_4_4Co_4_4B_4Zr_7Cu_1) with a similar structure, annealed at 600"oC. (author)

2001-09-23

316

Influence of second phase particles on fracture toughness in AZ31 magnesium alloys

In drug development, Caco-2 cells are often employed to study the influence of membrane transporters on drug permeability. The aim of the current study was to characterize permeability and kinetic parameters of selected organic anionic compounds in Caco-2 cells, and to investigate whether the Caco-2 cell line may be used as an overall model to predict interactions on multiple membrane transporters in the intestine. Taurocholic acid (TCA) and estrone-3-sulfate (E(1) S) were used as model substrates. Possible inhibitors studied were TCA, E(1) S, taurolithocholic acid, fluvastatin, and glipizide. The effects of these compounds on initial uptake, apparent permeability, and intracellular end-point accumulations of the probe substrates were studied. Both interactions on apical and basolateral influx transporters were observed. These interactions were proposed to be mediated mainly by the apical sodium-dependent bile acid transporter and the organic solute transporter ?/?, and to less extent ...

2011-05-23

317

Heat transfer and thermal performance analysis of a surface with hollow rectangular fins

Three kinds of thin AZ31 wrought magnesium alloys sheets were used in order to investigate the influence of the second phase particles on fracture toughness. From the theoretical model, the ratio of {lambda}{sub p}/d{sub p} would be estimated 5 {proportional_to} 6. On the other hand, from the microstructural observation, average particle spacing on each material was sample A: 13.1 {mu}m, sample B: 14.1, and sample C: 12 {mu}. In addition, average particle size on each sample was sample A: 2.1, sample B: 1.9, and sample C: 2.3 {mu}m. Therefore, the ratio of {lambda}{sub p}/d{sub p} calculated from fracture surface observation would be predicted 6 {proportional_to} 7. In comparison with the result of the prediction by theoretical analysis was in good agreement with the result of fracture toughness observation. It was found that the variation in plane-strain fracture toughness on AZ31 were affected by both of particle spacing and particle size. ...

2004-07-01

318

Further evidence supporting the concurrent influence of aflatoxin and manganese

An experimental study was conducted to investigate the heat transfer and friction loss characteristics in a horizontal rectangular channel having attachments of hollow rectangular profile fins over one of its heated surface. The Reynolds number based on the flow averaged inlet velocity and the hydraulic diameter, ranged from 3000 to 32,000. The hollow rectangular profile fins in 10cm height and axb=2cmx4cm dimensions with a thickness of 0.2cm were mounted on a heating surface vertically. Reynolds number, fin arrangement and fin pitch in the flow direction were the experimental parameters. Both in-line and staggered fin arrangements were studied for one-fixed spanwise (S{sub x}/a=3) and four different streamwise (S{sub y}/b=1.5, 1.875, 2.5 and 3.75) distances. Correlation equations for Nu, f and thermal performances were determined for fin configurations and the straight channel case without fins. (author)

2006-02-01

319

Effects of microwaves on the colony-forming capacity of haemopoietic stem cells in mice

Trace elements, including manganese may afford protection from deleterious effects of aflatoxin. Young male Fischer rats received ip injections of aflatoxin B1 (AFB1) in dimethyl sulfoxide (DMSO), 1 mg/kg, 2 mg/kg or 4 mg/kg. Control groups received DMSO ip or no injection. All animals were intubated with 3 microCi of (/sup 54/Mn)-MnCl/sub 2/ 12 hr post-injection. Sacrifice occurred 72 hr after gavage of the radiolabel. All tested levels of AFB1 affected the loss of total body radioactivity. This response was observed within 12 hr when toxin-treated groups excreted almost 4 times more counts than controls. From 12-36 hr following radiolabel administration, AFB1 appeared to enhance excretion; by 72 hr, toxin-treated animals (especially those receiving higher doses) appeared to conserve the metal. Aflatoxicosis manifested itself through reduced body weight gain. The data provide support evidence that Mn and AFB1 biointeract.

1987-04-01

320

Deforming the Maxwell-Sim algebra

A suspension of bone marrow cells from femurs of female (CBA . C57B1)F1 mice was exposed to 2450 MHz CW microwaves in a specially designed waveguide exposure system. The temperature of the suspension rose, during exposure to microwaves, from 20/sup 0/C to 45/sup 0/C, and at an interval within 20/sup 0/C to 45/sup 0/C the number of haemopoietic stem cells (CFUs) was determined by the spleen exocolony method. The time of exposure of bone marrow cells to each temperature studied was 20 s. Control suspensions of bone marrow cells were exposed to a water bath temperature. There were no significant effects of the CFUs with the water bath temperature, while after exposure to microwaves the number of spleen colonies was elevated with a nadir at the temperature of 37/sup 0/C. With a microwave-induced increase of the temperature above 41/sup 0/C the number of CFUs in the bone marrow suspension decreased. The increase in the number of colonies was related ...

1987-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

321

Coulomb and photo cross sections for nucleon emission by relativistic heavy ions and application to "4"0Ar on "8"9Y

The Maxwell algebra is a noncentral extension of the Poincare algebra, in which the momentum generators no longer commute, but satisfy [P?,P?]=Z??. The charges Z?? commute with the momenta, and transform tensorially under the action of the angular momentum generators. If one constructs an action for a massive particle, invariant under these symmetries, one finds that it satisfies the equations of motion of a charged particle interacting with a constant electromagnetic field via the Lorentz force. In this paper, we explore the analogous constructions where one starts instead with the ISim subalgebra of Poincare, this being the symmetry algebra of very special relativity. It admits an analogous noncentral extension, and we find that a particle action invariant under this Maxwell-Sim algebra again describes a particle subject to the ordinary Lorentz force. One can also deform the ISim algebra to DISimb, where b is a nontrivial dimensionless parameter. We find that the motion described by ...

2010-09-15

322

Competition of ferromagnetism and superconductivity in Sc3InB

The Coulomg-induced emission of nucleons by relativistic heavy ions is studied with respect to partial cross sections related to the various multipole orders of the electromagnetic field. Since the partial Coulomb cross sections can be factorized into the numbers of virtual photons and the photo cross sections, we first calculate the photo cross sections using the oscillator shell model and 1-particle-1-hole configurations. Then the Coulomb cross sections are obtained by folding the photo cross sections with the numbers of virtual photons. We apply the calculations to the Coulomb scattering of "4"0Ar ions on "8"9Y targets, where experiments at E_l_a_b=1.8 GeV/nucleon were carried out by Mercier et al. The contributions of the various multipole orders are discussed as functions of the projectile energy and the energy range of the emitted nucleons. Also methods for the separation of the most contributing multipole orders are developed. (orig.).

323

BNFL Report Glass Formers Characterization

We present results of electronic structure calculations for the intermetallic perovskite Sc3InB with the full-potential KKR-LDA method. Sc3InB is a very promising candidate for a new superconductor (related to 8 K MgCNi3) and can be regarded as a boron-inserted cubic Sc3In, which is a high-pressure allotropic form of the hexagonal weak ferromagnet Sc3In. We predict that cubic Sc3In can also be magnetic, whereas Sc3InB having large DOS in the vicinity of E F exhibits non-magnetic ground state. Estimation of the electron-phonon coupling for Sc3InB gives 1. Furthermore, the effect of vacancies in Sc3InB1-x and antisite disorder in Sc3(In-B) on critical parameters is also discussed using the KKR-CPA method. All theoretical results support the possibility of the superconductivity onset in Sc3InB. Preliminary experimental measurements established the transition temperature close to 4.5 K, with a very abrupt change in susceptibility and a correlated ...

2006-01-01

324

Analysis of pesticides in dried hops by liquid chromatography-tandem mass spectrometry.

The objective of this task was to obtain powder property data on candidate glass former materials, sufficient to guide conceptual design and estimate the cost of glass former handling facilities as requested under Part B1 of BNFL Technical and Development Support. Twenty-nine glass forming materials were selected and obtained from vendors for the characterization of their physical properties, durability in caustic solution, and powder flow characteristics. A glass former was selected based on the characterization for each of the ten oxide classes required for Envelope A, B, and C mixtures. Three blends (A, B, and C) were prepared based on formulations provided by Vitreous State Laboratory and evaluated with the same methods employed for the glass formers. The properties obtained are presented in a series of attached Tables. It was determined that five of the ten glass formers, (kyanite, iron oxide, titania, zircon, and zinc oxide) have the ...

2000-07-27

325

Alteration of the enterohepatic recirculation of bile acids in rats after exposure to ionizing radiation

An analytical method was developed for the determination of eleven agrochemicals [abamectin (as B1a), bifenazate, bifenthrin, carfentrazone-ethyl, cymoxanil, hexythiazox, imidacloprid, mefenoxam, pymetrozine, quinoxyfen, and trifloxystrobin] in dried hops. The method utilized polymeric and NH2 solid phase extraction (SPE) column cleanups and liquid chromatography with mass spectrometry (LC-MS/MS). Method validation and concurrent recoveries from untreated dried hops ranged from 71 to 126% for all compounds over three levels of fortification (0.10, 1.0, and 10.0 ppm). Commercially grown hop samples collected from several field sites had detectable residues of bifenazate, bifenthrin, hexythiazox, and quinoxyfen. The control sample used was free of contamination below the 0.050 ppm level for all agrochemicals of interest. The limit of quantitation and limit of detection for all compounds were 0.10 and 0.050 ppm, respectively. PMID:18593182

2008-07-02

326

Thermal spraying of reactive materials to form wear-resistant composite coatings

The aim of this work was to study acute alterations of the enterohepatic recirculation (EHR) of bile acids 3 days after an 8-Gy radiation exposure in vivo in the rat by a washout technique. Using this technique in association with HPLC analysis, the EHR of the major individual bile acids was determined in control and irradiated animals. Ex vivo ileal taurocholate absorption was also studied in Ussing chambers. Major hepatic enzyme activities involved in bile acid synthesis were also measured. Measurements of bile acid intestinal content and intestinal absorption efficiency calculation from washout showed reduced intestinal absorption with significant differences from one bile acid to another: absorption of taurocholate and tauromuricholate was decreased, whereas absorption of the more hydrophobic taurochenodeoxycholate was increased, suggesting that intestinal passive diffusion was enhanced, whereas ileal active transport might be reduced. Basal hepatic secretion was increased only for ...

2004-02-01

327

Theoretical approach to initial growth kinetics of GaN on GaN(001)

The dispersion of more than 20 vol pct submicrometer ceramic particles within a metallic matrix and the deposition of such a cermet to form a thick and tough coating presents problems. Most of the coating techniques have failed in attempting to homogeneously disperse very fine and hard particles in large amounts while avoiding their decomposition or reaction with the metal matrix during the deposition process. A simple and efficient method has been developed for producing ceramic-containing composite coatings. It consists in synthesizing cermet-based materials and in depositing them by a rapid solidification process, such as thermal spraying. Boride- and carbide-based materials have been successfully obtained by plasma spraying reactive powders comprising the basic reagents. These materials, with a microstructure of submicrometer ceramic particles dispersed in a metallic matrix, exhibit good wear-resistant properties (abrasion and sliding wear). Finally, reactive core wire arc spraying ...

1992-03-01

328

British Library Electronic Table of Contents (United Kingdom)

We carried out theoretical analyses based on ab initio calculations incorporates in which free energy of the vapor phase is incorporated in order to determine the initial growth kinetics of c-GaN on GaN(001)-(4x1). The feasibility of the theoretical approach had been confirmed by calculations of Ga adsorption-desorption transition temperature and transition beam equivalent pressures on the GaAs(001)-(4x2)b2 surface in our previous work [Y. Kangawa, T. Ito, A. Taguchi, K. Shiraishi, T. Ohachi, Surf. Sci. 493 (2001) 178]. The results of calculations suggest that no Ga adsorption occurs on the initial surface under typical growth conditions but that a Ga adsorption site appears after N adsorption on GaN(001)-(4x1). That is, in the initial growth stage of c-GaN on GaN(001)-(4x1), a N-adsorbed ...

2007-01-01

329

Structural studies of some phospho-borate glasses using ultrasonic pulse-echo technique, DSC and IR spectroscopy

Spark plasma sintered tantalum carbide: Effect of pressure and nano-boron carbide addition on microstructure and mechanical properties

Glasses in the system (95-x) [0.25 Na2O-0.75 B2O3]-x P2O5-5 Fe2O3 (0?x?15 mol%), have been prepared by the melt quenching technique. Elastic properties and FT-IR spectroscopic studies have been employed to study the role of P2O5 on the structure of the glass system. Elastic properties Poisson's ratio, micro-hardness and Debye temperature have been investigated using sound wave velocity measurements at 4 MHz (both longitudinal and shear) at room temperature. The results showed that the density and the molar volume increase as both sound velocities and the determined glass transition temperatures decrease with increasing the contents of P2O5. Infrared spectra of the glasses reveal that the borate network consists of diborate units and is affected by the increase in the concentration of P2O5 content as a second network former. These results are interpreted in terms of the replacement of the diborate units with B-O-B bridges by phosphate units with ...

2009-06-01

330

British Library Electronic Table of Contents (United Kingdom)

TaC and TaC-1wt.% B4C powders were consolidated using spark plasma sintering (SPS) at 1850^oC and varying pressure of 100, 255 and 363MPa. The effect of pressure on the densification and grain size is evaluated. The role of nano-sized B4C as sintering aid and grain growth inhibitor is studied by means of XRD, SEM and high resolution TEM. Fully dense TaC samples were produced at a pressure of 255MPa and higher at 1850^oC. The increasing pressure also resulted in an increase in TaC grain size. Addition of B4C leads to an increase in the density of 100MPa sample from 89% to 97%. B4C nano-powder resists grain growth even at high pressure of 363MPa. The formation of TaB2/Carbon at TaC grain boundaries helps in pinning the grain boundary and inhibiting grain growth. The effect of B4C addition on...

2011-01-01

331

On the band gap dependence of refractive indices of some quaternary III-V and II-VI compounds of device interest

Magnetic properties of Pr_2PdSi_3 single crystals

The credibility of the model proposed by Ghosh in predicting the refractive indices of mixed semiconductor crystals of technological importance within their miscibility range as a function of band gap is demonstrated. The high-frequency refractive indices of four quaternary alloys Al_xGa_1_-_x_-_yIn_yP (y = 0.49, 0 #<=# x #<=# 0.51), InSb_xAs_1_-_x_-_yP_y (y = 2.2x, 0 #<=# x #<=# 0.313, 0 #<=# y #<=# 0.638), Cd_xZn_1_-_x_-_yHg_ySe (x + y = 1, 0.153 #<=# x #<=# 0.684, 0.316 #<=# y #<=# 0.847), and CdS_1_-_x_-_ySe_xTe_y (x + y = 1, 0.15 #<=# x #<=# 0.93, 0.07 #<=# y #<=# 0.85) are calculated according to the relation n"2-1 = A/(E_g + B)"2 where A is an energy gap dependent constant and B is a constant depending on crystal ionicity. The calculated values show excellent agreement with the experimental data thus justifying the validity of the model.

332

Lysozyme dimer formation on lysozyme oxidation with B./2 as studied by fluorescence evolution

Ternary R_2TSi_3 intermetallic compounds (R=Rare Earth, T=Transition Metal) with hexagonal AlB_2-type crystallographic structure are known because of their interesting physical properties. Pr_2PdSi_3 single crystals were grown by a vertical floating zone method. The compound exhibits congruent melting behavior at a liquidus temperature of about 1770 C. Single crystalline samples show a huge anisotropy at low temperatures due to the crystal electric field effect and order antiferromagnetically below the Neel temperature T_N=2.17 K. This value approximately obeys the linear de Gennes scaling for this class of compounds. The [001] orientation was identified as the magnetic easy axis at room temperature. At lower temperature (#approx#20 K) magnetic easy and hard axes interchange with each other. Two additional magnetic phase transitions were observed at temperatures below 1 K.

2010-03-21

333

Is nest-drifting behaviour an insurance policy for maximising indirect fitness in primitively eusocial paper wasps?

Lysozyme dimers produced on oxidation of lysozyme with Br_2anion radicals in aqueous solutions exhibit a fluorescence spectrum (lambdasub(max) = 400 nm) closely similar to that of bi-tyrosine. This suggests that the dimer is likely to have a tyrosine-tyrosine bond resulting from the combination of tyrosine phenoxy radicals of two lysozyme molecules. Kinetic studies on dimer formation were made by measuring time-dependent fluorescence after pulsed-electron irradiation over wide pH range. The results lead to the following conclusions. The second-order growth of the dimer fluorescence observed at pH 10.7-12.5 reflects the combination process of the lysozyme radicals, which is rate-determining in the pH range. On the other hand, the first-order growth observed at pH 6.8-10.2 is attributable to the enolization of the keto-form of the dimer. A tentative reaction scheme is proposed for the dimer formation. (author).

334

Environmental Research Database

ObjectivesThe main objectives of this project are: 1. To determine whether nest-drifting behaviour allows helpers to maximise their indirect fitness in the paper wasp Polistes canadensis. Specifically, I will test a) whether nest-drifters apportion helping effort in relation to the productivity benefits of different nests (hypothesis 1a), and b) whether nest-drifters can adjust their investment in response to changes in the productivity payoffs of different nests (hypothesis 1b). 2. To determine [continued...]DescriptionDarwin's theory of natural selection predicts that organisms should act selfishly in order to pass on as many of their genes to the next generation as possible. The evolution of social behaviour is a paradox because it requires that some individuals forgo reproduction in order to help raise the offspring of others. Explaining the evolution of helping behaviour in animal societies has been a major focus for evolutionary ...

2011-01-20

335

Glass-ceramic sealants for solid oxide fuel cells: Part I. Physical properties

Elastic properties and structural studies on some zinc-borate glasses derived from ultrasonic, FT-IR and X-ray techniques

A family of sealant materials has been developed for use in the solid oxide fuel cell (SOFC) and in other applications in the temperature range of 800 endash 1000 degree C. These materials are based on glasses and glass-ceramics in the SrO endash La_2O_3 endash Al_2O_3 endash B_2O_3 endash SiO_2 system. The coefficients of thermal expansion (CTE) for these materials are in the range of 8 endash 13x10"-"6/degree C, a good match with those of the SOFC components. These sealant materials bond well with the ceramics of the SOFC and, more importantly, form bonds that can be thermally cycled without failure. At the fuel cell operating temperature, the sealants have viscosities in the range of 10"4-10"6 Pa-s, which allow them to tolerate a CTE mismatch of about 20% among the bonded substrates. The gas tightness of a sample seal was demonstrated in a simple zirconia-based oxygen concentration cell. copyright 1996 Materials Research Society.

336

Effect of heat transfer augmentation by square rod array in impinging air jet system(heat transfer characteristic of potential core region)

Glasses in the system (1 - x) [29Na2O- 4Al2O3- 67B2O3]- xZnO (0 ? x ? 35 mol%), have been prepared by the melt quenching technique. Elastic properties, X-ray and FT-IR spectroscopic studies have been employed to study the role of ZnO on the structure of the investigated glass system. Elastic properties and Debye temperature have been investigated using sound wave velocity measurements at 4 MHz at room temperature. The results showed that the density increases and the molar volume decreases while both sound velocities and the determined glass transition temperatures decrease with increase in x. X-ray and infrared spectra of the glasses reveal that the borate network consists of diborate units and is affected by the increase in the concentration of ZnO content. These results are interpreted in terms of the decrease in the N4 values (fraction of tetrahedral coordinated boron atoms), and substitution of longer bond lengths of Zn-O in place of ...

2009-05-05

337

Alternate alloying for environmental resistance; Proceedings of the Symposium, New Orleans, LA, Mar. 2-6, 1986

This research has been proceeded over the potential core region (H/B=2) of two-dimensional impinging air jet system, in which square rods(width of 6 mm) has been set up in front of heating surface in order to increase heat transfer. The objective of this research was to investigate the characteristics of heat transfer and air flow, in cases of the clearance from rods to heating surface (C = 1, 2, 4, 6 mm) and the pitch between each rods(P = 30, 40, 50 mm) changed. And this research compared the above with the experimentation without rods. As result, heat transfer performance was best under the condition of C = 1 mm, in case clearance changed, and there was no serious difference in the effect of heat transfer augmentation in the case of pitch of rods changed. (author) 11 refs. 12 figs.

1995-07-01

338

Ultrashallow P"+/N junction formation by plasma ion implantation

Papers are presented on the development of oxidation- and sulfidation-resistant ferritic alloys; the microstructural stability of sulfidation-resistant FeCrAl stainless steels around 500 C; age hardening in Fe-Mn-Al-C austenitic alloys; the oxidation/corrosion behavior of low-Cr Fe-Cr-Ni alloys containing Zr or Nb; the high temperature oxidation/corrosion of iron-based superalloys; and the role of Mo in the Na/sub 2/SO/sub 4/ induced corrosion of superalloys at high temperature. Topics discussed include the effect of variations of Co content on the cyclic oxidation resistance of selected Ni-base superalloys; high temperature oxidation of Fe based alloys; the morphological development of high temperature oxide scales of Fe-Mn-Al base alloys; and the oxidation of an Fe-Mn-Al-C alloy at 1000 C. Consideration is given to the corrosion properties of Fe-Mn-Al alloys; passive films formed on nonmagnetic Cr-Mn-N stainless steels in chloride containing environments; the tubo 25 nickel base ...

1987-01-01

339

Synthesis, crystal structure and optical properties of a novel sodium lead pentaborate, NaPbB5O9

We investigated the electrical characteristics and the junction depth of ultra-shallow junctions formed by using the plasma-doping method. Compared with ultra-low energy boron-ion implantation at 500 eV, the junctions formed with the plasma-doping process exhibited shallow junction depths and low sheet resistances. The junction depths of the plasma-doped samples were 150 A and 330 A after annealing for 10 s at 900 .deg. C and 950 .deg. C, respectively. For the same junction depth, the sheet resistance of the B_2H_6 plasma-doped sample was an order of magnitude less than that of the 500-eV B-ion implanted sample. Cross-sectional transmission electron microscopy and deep level transient spectroscopy showed that the defects formed by the B_2H_6 plasma-doping process could be removed by annealing at 950 .deg. C for 10 s. The scaling of metal-oxide-semiconductor field-effect-transistor (MOSFET) device ...

2000-12-01

340

Three-step photoionization of mercury for application to separation of mercury isomers

A novel sodium lead pentaborate, NaPbB5O9, has been successfully synthesized by standard solid-state reaction. The single-crystal X-ray structural analysis showed that NaPbB5O9 crystallizes in the monoclinic space group P21/c with a=6.5324(10) A, b=13.0234(2) A, c=8.5838(10) A, ?=104.971(10)o, and Z=4. The crystal structure is composed of double ring [B5O9]3- units, [PbO7] and [NaO7] polyhedra. [B5O9]3- groups connect with each other forming two-dimensional infinite ?[B5O9]3- layers, while [PbO7] and [NaO7] polyhedra are located between the layers. [PbO7] polyhedra linked together via corner-sharing O atom forming novel infinite ?[PbO6] chains along the c axis. The thermal behavior, IR spectrum and the optical diffuse reflectance spectrum of NaPbB5O9 were reported. -- Graphical abstract: A new phase, NaPbB5O9, has been discovered in the ternary M2O-PbO-B2O3 (M=alkali-metal) system. The crystal structure consists of a novel infinite ?[PbO6] ...

2011-04-01

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341

T=(5/2) "2"7Na from "1"4C+"1"4C, and the N=16 shell gap

Development of techniques for separating isomeric nuclides is important to the investigation of schemes for gamma-ray lasers. In preparation for an experiment to separate 10_1_4 atoms of the /sub 197m/Hg (299 keV, tau/sub 1/2/ = 24 hours) isomer, we report isotopically selective resonance ionization of mercury atoms. This has been accomplished by three-step excitation via the 6_3P"1 and 8_1S"0 excited states, using three collinear pulsed laser beams of 254, 286, and 532 nm wavelengths from a Nd:YAG and two dye lasers. These beams were passed through a closed mercury-vapor cell containing electrostatic plates to which the ions were drawn. Ion current and fluorescent radiation were measured as a function of laser frequency. Hyperfine structures for the 254- and 286-nm transitions were observed.

342

Optical Feshbach Resonances in Alkaline Earth Atoms

For the first time a comprehensive level and decay scheme has been obtained for a T=(5/2) nucleus in the s-d shell ("2"7Na) by using a radioactive beam and target. Particle-#gamma# and p-#gamma#-#gamma# coincidences were measured following the "1"4C("1"4C,p#gamma#)"2"7Na reaction at E_l_a_b=22 MeV. The results do not support an inversion of the 2s_1_/_2 and 1d_5_/_2 orbitals, as previously proposed for T_z#>=#3, but they do suggest an increased N=16 gap between the 2s_1_/_2 and 1d_3_/_2 orbitals due to the neutron excess. A consistent interpretation of the level scheme in terms of the s-d shell model using the USD Hamiltonian is possible below 4 MeV, but differences increase at higher excitation energies. Another interpretation is that the influences of both the p_1_/_2 and f_7_/_2 intruder orbitals increase simultaneously with increasing T, an effect not included in the USD Hamiltonian.

2002-05-01

343

Observation of two charged bottomonium-like resonances

Recent proposals have shown that a quantum degenerate gas of alkaline earth atoms can be used for a number of novel quantum computing and quantum simulation experiments. Strontium is a good candidate for such experiments because it can be controlled with high precision, as demonstrated in recent atomic clock experiments. Unfortunately, the small scattering length of strontium is not amenable to evaporative cooling techniques that are used to reach quantum degeneracy. Furthermore, increasing the scattering length of alkaline earths with a magnetic Feshbach resonance is not possible due to their spinless electronic ground state configuration. However, recent theoretical and experimental work suggests the possibility of changing scattering lengths in alkaline earths with laser light. Using this optical Feshbach resonance near strontium's narrow ^1S0->^3P1 intercombination transition might allow its scattering length to be controlled without ...

2009-10-01

344

Inclusive K{sup +}-meson production in proton-nucleus interactions

We report the observation of two narrow structures at 10610MeV/c^2 and 10650MeV/c^2 in the pi^{\\pm}Upsilon(nS) (n=1,2,3) and pi^{\\pm}h_b(mP) (m=1,2) mass spectra that are produced in association with a single charged pion in Upsilon(5S) decays. The measured masses and widths of the two structures averaged over the five final states are M_1=10608.4\\pm2.0MeV/c^2, Gamma_1=15.6\\pm2.5MeV and M_2=10653.2\\pm1.5MeV/c^2, Gamma_2=14.4\\pm3.2MeV. Analysis favors quantum numbers of I^G(J^P)=1^+(1^+) for both states. The results are obtained with a 121.4fb^{-1} data sample collected with the Belle detector near the Upsilon(5S) resonance, at the KEKB asymmetric-energy e+e- collider.

2011-01-01

345

Hot Nights on Extrasolar Planets: Mid-IR Phase Variations of Hot Jupiters

The production of K{sup +}-mesons in pA(A=D,C,Cu,Ag,Au) collisions has been investigated at the COoler SYnchrotron COSY-Juelich for beam energies T{sub p}=1.0-2.3 GeV. Double differential inclusive pC cross-sections at forward angles {theta}{sub K+}<12 as well as the target mass dependence of the K{sup +} momentum spectra have been measured with the ANKE spectrometer. Far below the free NNthreshold at T{sub NN}=1.58 GeV the spectra reveal a high degree of collectivity in the target nucleus. From the target mass dependence of the cross-sections at higher energies, the repulsive in-medium potential of the K{sup +}-mesons can be deduced. Using pNcross-section parameterisations from the literature and our measured pD data we derive a cross-section ratio {sigma}(pn{yields}K{sup +}X)/{sigma}(pp{yields}K{sup +}X) {proportional_to}(3-4). (orig.)

2004-11-01

346

Histological changes in the ovaries of the females in three filial generations of spodoptera littoralis (boisd.) after being irradiated as full- grown Male pupae

We present results from Spitzer Space Telescope observations of the mid-infrared phase variations of three short-period extrasolar planetary systems: HD 209458, HD 179949 and 51 Peg. We gathered IRAC images in multiple wavebands at eight phases of each planet's orbit. We find the uncertainty in relative photometry from one epoch to the next to be significantly larger than the photon counting error at 3.6 micron and 4.5 micron. We are able to place 2-sigma upper limits of only 2% on the phase variations at these wavelengths. At 8 micron the epoch-to-epoch systematic uncertainty is comparable to the photon counting noise and we detect a phase function for HD 179949 which is in phase with the planet's orbit and with a relative peak-to-trough amplitude of 0.00141(33). Assuming that HD 179949b has a radius R_J < R_p < 1.2R_J and a small Bond albedo, it must recirculate less than 30% of incident stellar energy to its night side at the 1-sigma ...

2007-01-01

347

Generalized support varieties for finite group schemes

the cotton leaf worm, Spodoptera littoralis (boisd.) were irradiated with 100,150 and 200 Gy to induce inherited sterility. the effects of the tested doses applied to these pupae through three consequent fillial generations and the retarded influence on their F_1,F_2 and F_3 generations progeny were examined . irradiation of parental male induced damage to their daughter females ovaries. the overioles of females among P_1 ,F_1 and F_2 generations showed that the follicular epithelial cells appeared abnormal beside their limited separation from developing oocytes which became shrinked, semi absorbed or completely absorbed leaving vacuoles. the nurse cells were reduced or absent in some parts. damage was obvious through the first and second generations especially at 150 and 200 Gy. in the third generation, ovaries were not greatly affected

2004-02-01

348

Effects of relativity and 'atomic structure' in the KLL Auger spectrum of "8"8Sr generated in the EC-decay of "8"8Y

We construct two families of refinements of the (projectivized) support variety of a finite dimensional module $M$ for a finite group scheme $G$. For an arbitrary finite group scheme, we associate a family of {\\it non maximal rank varieties} $\\Gamma^j(G)_M$, $1\\leq j \\leq p-1$, to a $kG$-module $M$. For $G$ infinitesimal, we construct a finer family of locally closed subvarieties $V^{\\ul a}(G)_M$ of the variety of one parameter subgroups of $G$ for any partition $\\ul a$ of $\\dim M$. For an arbitrary finite group scheme $G$, a $kG$-module $M$ of constant rank, and a cohomology class $\\zeta$ in $\\HHH^1(G,M)$ we introduce the {\\it zero locus} $Z(\\zeta) \\subset \\Pi(G)$. We show that $Z(\\zeta)$ is a closed subvariety, and relate it to the non-maximal rank varieties. We also extend the construction of $Z(\\zeta)$ to an arbitrary extension class $\\zeta \\in \\Ext^n_G(M,N)$ whenever $M$ and $N$ are $kG$-modules of constant Jordan type.

2011-01-01

349

A novel small-molecule inhibitor of NF-#kappa#B signaling

The KLL Auger electron spectrum of "8"8Sr generated in the EC-decay of "8"8Y has been analyzed at the instrumental resolution of 11 eV using a combined electrostatic spectrometer. Energies and relative intensities of the all nine transitions were determined and compared with theoretical predictions. Our value of 12067.3(12) eV measured for the absolute energy of the dominant KL_2L_3("1D_2) transition was found to be higher by 7.4 eV (i.e., more than 3#sigma#) than that one obtained in a measurement with external excitation. The discrepancy indicates substantial influence of the 'atomic structure effect' on absolute transition energies in our experiment. Very good agreement of the measured 0.14(3) and predicted 0.12 values for the KL_1L_2("3P_0/"1P_1) Auger transition intensity ratio clearly proved the predicted strong influence of the relativistic effects on the KL_1L_2("3P_0) transition rate even at Z = 38.

2007-08-01

350

Transient enhanced diffusion from decaborane molecular ion implantation

The inducible transcription factor NF-#kappa#B regulates divergent signaling pathways including inflammatory response and cancer development. Selective inhibitors for NF-#kappa#B signaling are potentially useful for treatment of inflammation and cancer. NF-#kappa#B is canonically activated by preferential disposal of its inhibitory protein; I#kappa#B, which suppresses the nuclear translocation of NF-#kappa#B. I#kappa#B#alpha# (a major member of I#kappa#B family proteins) is phosphorylated with an I#kappa#B kinase (IKK) and subsequently polyubiquitylated by SCF"#beta#"T"r"C"P"1 ubiquitin-ligase in the presence of E1 and E2 prior to proteasomal degradation. Here, we describe a novel inhibitor termed GS143, which suppressed I#kappa#B#alpha# ubiquitylation, but not I#kappa#B#alpha# phosphorylation, MDM2-directed p53 ubiquitylation, and proteasome activity in vitro. GS143 markedly suppressed the destruction of I#kappa#B#alpha# stimulated by ...

2008-04-18

351

The effect of ethanol on "3"5-S-TBPS binding to mouse brain membranes in the presence of chloride

Transient enhanced diffusion (TED) from implantation of 5keVB_1_0H_1_4 and 0.5 keV B ions has been quantified and compared for nominal boron doses of 10"1"4 and 10"1"5cm"-"2. Boron diffusivity during annealing was extracted from secondary ion mass spectroscopy depth profiles of diffused marker layers in boron doping-superlattices and the actual implanted B dose was independently measured by nuclear reaction analysis. Comparable enhancements were observed from both ions. Transmission electron microscopy analysis revealed that both boron- and decaborane-implanted samples were amorphized at a nominal 10"1"5cm"-"2B dose. A comparison with data from low energy Si implants revealed a similar dependence of diffusivity enhancement on implant dose. These findings are consistent with the understanding that TED is caused by the interstitial supersaturation resulting from a number of excess interstitials approximately equal to the number of implanted atoms which can become substitutional in the ...

1998-10-01

352

Proteomic Profiling of Mesenchymal Stem Cell Responses to Mechanical Strain and TGF-B1

The effect of in vitro and in vivo administration of ethanol on the binding of "3"5S-t-butyl-bicyclophosphorothionate ("3"5S-TBPS) to cortical brain membranes of C57B1 mice was investigated using KCl (100 mM) containing assay media. The in vitro addition of ethanol produced a dose-dependent inhibition of basal "3"5S-TBPS binding. In the presence of chloride ions, GABA and pentobarbital had a biphasic action (stimulation followed by inhibition) on "3"5S-TBPS binding, whereas diazepam only stimulated the binding. Ethanol reduced the stimulatory effects of GABA and pentobarbital in a dose-dependent manner, but had no effect on the enhancement of "3"5S-TBPS binding produced by diazepam. "3"5S-TBPS binding to cortical brain membranes was inhibited by the putative Cl"- channel blocking agent DIDS. This inhibitory action of DIDS was significantly, and dose-dependently reduced by ethanol (#<=# 100 mM ethanol). Chronic ethanol ingestion in vivo, ...

353

Prospects and future of conservative management of beta thalassemia major in a developing country

Mesenchymal stem cells (MSCs) are a potential source of smooth muscle cells (SMCs) for constructing tissue-engineered vascular grafts. However, the details of how specific combinations of vascular microenvironmental factors regulate MSCs are not well understood. Previous studies have suggested that both mechanical stimulation with uniaxial cyclic strain and chemical stimulation with transforming growth factor {beta}1 (TGF-{beta}1) can induce smooth muscle markers in MSCs. In this study, we investigated the combined effects of uniaxial cyclic strain and TGF-{beta}1 stimulation on MSCs. By using a proteomic analysis, we found differential regulation of several proteins and genes, such as the up-regulation of TGF-{beta}1-induced protein ig-h3 (BGH3) protein levels by TGF-{beta}1 and up-regulation of calponin 3 protein level by cyclic strain. At the gene expression level, BGH3 was induced by TGF-{beta}1, but calponin 3 was not significantly regulated by mechanical strain or TGF-{beta}1, ...

2009-10-12

354

Projected change in climate thresholds in the Northeastern U.S.: implications for crops, pests, livestock, and farmers

Objective: To assess the efficacy, prospects and future of conservative management of beta thalassemia major patients in a developing country. Design: Patients registered at IHBTS were studied over a period of three years. They consented to being managed on moderate transfusion regimen, aiming to maintain a pre-transfusion haemoglobin(Hgb) level of 9.0 plus minus 1.0 g per dL. We studied their transfusion requirements, status for transfusion transmitted infections (TTls), serum ferritin levels and complications developing as a result of iron overload. Subjects: Initially all registered patients were included in this study. Sporadic patients as well as dropouts occurring due to any reason, (patients concurrently seeking treatment at other centres as well, or complying poorly to advised chelation therapy) were excluded from the study. The data presented here conforms to a cohort of 60 regular patients who adhered best to our selection criteria. Main Outcome Measures: 1) The study ...

2004-01-01

355

Photodissociation dynamics of doubly excited Rydberg states of molecular hydrogen

Most prior climate change assessments for U.S. agriculture have focused on major world food crops such as wheat and maize. While useful from a national and global perspective, these results are not particularly relevant to the Northeastern U.S. agriculture economy, which is dominated by dairy milk production, and high-value horticultural crops such as apples (Malus domestica), grapes (vitis vinifera), sweet corn (Zea mays var. rugosa), cabbage (Brassica oleracea var. capitata), and maple syrup (sugar maple, Acer saccharum). We used statistically downscaled climate projections generated by the HadCM3 atmosphere-ocean general circulation model, run with Intergovernmental Panel on Climate Change future emissions scenarios Alfi (higher) and B1 (lower), to evaluate several climate thresholds of direct relevance to agriculture in the region. A longer (frostfree) growing season could create new opportunities for farmers with enough capital to take ...

2008-07-01

356

Gel-based proteomics of liver cancer progression in rat.

We have applied photofragment ion imaging to investigate the dissociation dynamics of low-lying, doubly excited states of molecular hydrogen. A doubly excited electronic state is one in which both of the hydrogen electrons reside in excited molecular orbitals. Two-step, two-color multiphoton excitation of H_2, first via 201.8 nm, two-photon excitation into the E, F "1#SIGMA#"+_g(v_E=0, J=1) state, followed by #approx#563 nm, 1+m (m=1, 2) excitation through the B double-prime "1#SIGMA#"+_u(v=0, J=0, 2), D "1#PI#_u(v=2, J=1, 2), and B' "1#SIGMA#"+_u(v=4, J=0, 2) states provides a ready means of populating several low-lying doubly excited states of H_2 at increasing internuclear separations. From these doubly excited repulsive states, both dissociation and autoionization processes are possible. Because the excitation energy remains relatively constant as each intermediate state is accessed, differences in the photodissociation dynamics via each ...

357

Chemopreventive effects of Furan-2-yl-3-pyridin-2-yl-propenone against 7,12-dimethylbenz[a]anthracene-inducible genotoxicity

A significant challenge in proteomics biomarker research is to identify the changes that are of highest diagnostic interest, among the many unspecific aberrations associated with disease burden and inflammation. In the present study liver tissue specimens (n=18) from six experimental stages were collected from the resistant hepatocyte (RH) rat model of liver cancer and analyzed by 2D DIGE. The study included triplicates of regenerating liver, control "sham-operated" liver, three distinct premalignant stages and hepatomas. Out of 81 identified proteins two-thirds were differentially abundant in rat hepatomas compared to control rat liver and, secondly, the majority of proteins were also changed in precursor stages. This underscores the importance of adequate control samples in explorative cancer biomarker research. We confirm several proteomic changes previously identified in human hepatocellular carcinoma (HCC) and we identify novel candidate proteomic aberrations for further analysis ...

2011-06-06

358

THE STATE OF STAR FORMATION AND THE INTERGALACTIC MEDIUM AT z #approx# 6

1-Furan-2-yl-3-pyridin-2-yl-propenone (FPP-3) is an anti-inflammatory agent with a propenone moiety and chemically synthesized recently. In this study, we examined the chemopreventive effect of FPP-3 on 7,12-dimethylbenz[a]anthracene (DMBA)-induced genotoxicity in MCF-7 cells. FPP-3 reduced the formation of the DMBA-DNA adduct. DMBA-induced CYP1A1 and CYP1B1 gene expression and enzyme activity were inhibited by FPP-3. It inhibited DMBA-induced aryl hydrocarbon receptor (AhR) transactivation and DMBA-inducible nuclear localization of the AhR. Induction of detoxifying phase II genes by chemopreventive agents represents a coordinated protective response against oxidative stress and neoplastic effects of carcinogens. Transcription factor NF-E2 related factor 2 (Nrf2) regulates antioxidant response element (ARE) of phase II detoxifying and antioxidant enzymes, such as glutathione S-transferase (GST) and NAD(P)H:quinone oxidoreductase (QR). FPP-3 ...

2008-05-01

359

Prostaglandin (PG) E3 synthesis elicted by adrenergic stimuli in guinea-pig trachea (GPT) is mediated primarily by B2 adrenergic receptors

In the context of stellar reionization in the standard cold dark matter model, we analyze observations at z #approx# 6 and are able to draw three significant conclusions with respect to star formation and the state of the intergalactic medium (IGM) at z #approx# 6. (1) An initial stellar mass function (IMF) more efficient, by a factor of 10-20, in producing ionizing photons than the standard Salpeter IMF is required at z #approx# 6. This may be achieved by having either (a) a metal-enriched IMF with a lower mass cutoff of #>=#30 M_s_u_n or (b) 2%-4% of stellar mass being Population III massive metal-free stars at z #approx# 6. While there is no compelling physical reason or observational evidence to support (a), (b) could plausibly be fulfilled by continued existence of some pockets of uncontaminated, metal-free gas for star formation. (2) The volume-weighted neutral fraction of the IGM of _V#approx#10"-"4 at z = 5.8 inferred ...

2010-12-10

360

Prostaglandin (PG) E3 synthesis elicted by adrenergic stimuli in guinea-pig trachea (GPT) is mediated primarily by B2 adrenergic receptors

The purpose of this study was to examine arachidonic acid (AA) metabolism and to characterize the type of adrenergic receptor (AR) involved in the production of the major metabolite of this fatty acid. ({sup 14}C)AA was incubated with GPT-rings and the radiolabelled products were extracted and separated by TLC method. The medium was also assayed for radiolabelled immunoreactive PG's (iPG's) and leukotrienes (LT) B4 and C4 by RIA or Enzyme immunoassay (EIA) after exposure to various AR agonists. ({sup 14}C)AA was incorporated into GPT-rings and metabolized mainly into iPGE2 and smaller amounts into PGF2{alpha}. Trace amounts of PGD2 and 6-keto-PGF1{alpha} but not LTB4 or LTC4 were detected by RIA and/or EIA. Incubation of GPT rings for 15 minutes with isoproterenol and salbutamol resulted in a significant increase of PGE2 synthesis (optimum conc: 10{sup {minus}7}, 10{sup {minus}7}M respectively). In contrast, dobutamine, norepinephrine, phenylnephrine and xylazine (up ...

1990-02-26

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361

Properties of plutonium-contaminated particles resulting from British Vixen B trials at Maralinga

The purpose of this study was to examine arachidonic acid (AA) metabolism and to characterize the type of adrenergic receptor (AR) involved in the production of the major metabolite of this fatty acid. ["1"4C]AA was incubated with GPT-rings and the radiolabelled products were extracted and separated by TLC method. The medium was also assayed for radiolabelled immunoreactive PG's (iPG's) and leukotrienes (LT) B4 and C4 by RIA or Enzyme immunoassay (EIA) after exposure to various AR agonists. ["1"4C]AA was incorporated into GPT-rings and metabolized mainly into iPGE2 and smaller amounts into PGF2#alpha#. Trace amounts of PGD2 and 6-keto-PGF1#alpha# but not LTB4 or LTC4 were detected by RIA and/or EIA. Incubation of GPT rings for 15 minutes with isoproterenol and salbutamol resulted in a significant increase of PGE2 synthesis (optimum conc: 10"-"7, 10"-"7M respectively). In contrast, dobutamine, norepinephrine, phenylnephrine and xylazine (up to 10"-"6M) did not significantly increase ...

1991-04-21

362

Preparation and Crystal Structure of the Equiatomic Rare Earth Palladium Silicides NdPdSi, SmPdSi, alpha-GdPdSi, and alpha-TbPdSi

Since 1984 a number of studies have been performed to investigate residual contamination at the former atomic weapons test site at Maralinga in South Australia, and to aid in the rehabilitation of the area. The largest site of plutonium contamination at Maralinga results from twelve Vixen B trials conduced at Taranaki in 1960, 1961 and 1963. Plutonium was dispersed along four major plumes from these trials. Measurements of the ratios of activities of "2"3"9Pu and "2"4"0Pu to "2"4"1Am are presented for the plumes. These are identified with individual trials where possible. Some measurements have also been made of "2"3"5U activities. An examination of meteorological and health physics survey data suggests that the most extensive part of the north-west plume results from a single trial, viz. Vixen B2 round 5 of 1961. It appears that the level of contamination in this plume was augmented by rainout of material, and the extent of the plume was ...

1997-05-01

363

Novel method for differentiation between Trastuzumab and host adaptive response.

The title compounds were prepared by arc-melting of the elemental components. Whereas NdPdSi and SmPdSi are already present after the arc-melting, alpha-GdPdSi and alpha-TbPdSi are formed only during the annealing at 800 degC. The four compounds crystallize with the recently reported alpha-YbAuGe type structure, which was refined for alpha-GdPdSi: Pnma, a=2108.0(4) pm, b=433.9(1) pm, c=745.6(1) pm, Z=12, R=0.026 for 1447 structure factors and 62 variable parameters. The lanthanoid atoms are situated between two-dimensionally infinite nets of condensed, puckered hexagons formed by alternating palladium and silicon atoms, with Pd-Si distances varying between 251 and 262 pm. In the third dimension these nets are linked via weak Pd-Pd (300 pm), Pd-Si (283 pm), and Si-Si bonds (261 pm). The refinements of the occupancy parameters suggested that ca. 2% of the palladium sites are occupied by silicon atoms and vice versa. The structural relationships between the two modifications of GdPdSi and ...

1999-01-01

364

Magnetic excitations in R_2PdSi_3 studied by inelastic neutron scattering

Humoral immune response to human epidermal growth factor receptor 2 (HER-2/neu or ErbB-2) has been detected in sera of breast cancer patients and shown to be an appropriate prognostic marker (Taylor et al., 2007). However, since Trastuzumab (Herceptin) is a widely used monoclonal antibody as cancer therapy agent for tumors over-expressing HER-2, there is a need for an efficient way to detect host-generated antibodies against HER-2 without the confounding effect of Herceptin. Here we describe a screening method developed to decipher between host antibodies against HER-2 and that of Herceptin. By producing a series of truncation mutants within the epitope of Herceptin, we were able to inhibit this binding. We demonstrated also that by a three amino acid substitution (PPF?SSS) we were able to abrogate Herceptin binding while generating a highly conserved HER-2 extracellular domain (ECD). By producing a stable cell line that expresses this mutated ...

2011-06-08

365

Incineration of wool-scouring sludge in a vertical-axis-spinning fluidised-bed incinerator

R_2PdSi_3 compounds have been found to exhibit rich magnetic phenomena arising from the interplay between RKKY interaction, crystal electric field effects and geometric frustration due to the derived hexagonal AlB_2 structure. The observed crystallographic superstructure further complicates the CEF level scheme. Inelastic neutron scattering measurements on single crystals of Tm_2PdSi_3 and Er_2PdSi_3 have been performed at the cold triple axis spectrometer PANDA in FRM-II. Both compounds order antiferromagnetically at T_N=7 K and 2.1 K respectively; Er_2PdSi_3 undergoes a second phase transition at T_2=2 K. Several low lying CEF excitations (below 10 meV) were observed. The intensity of the lowest excitation show strong directional dependence (in HK0 plane for Er_2PdSi_3 and in HHL plane for Tm_2PdSi_3), from which the details of the transitional matrix could be deduced. Measurements in magnetic fields up to 13 T show Zeeman splitting of the ...

2009-03-22

366

Floating zone crystal growth of selected R2PdSi3 ternary silicides

The main purposes of this research was to investigate the feasibility of incineration of wool-scouring sludge in a novel vertical-axis-rotating fluidised bed (RFB). The experiment was carried out in a RFB with an internal diameter (ID) of 200 mm and height of 50 mm. A cold test was first conducted to investigate the fluidization performance of the RFB via parameters such as the bubbling, gas distribution, bed shape and pressure drop. The tumbling phenomena was observed in the bed, and this effectively enhanced the axial mixing. The appropriate range of bed thickness, rotating speed and sand particle size were identified to ensure the full fluidization and reduce the particle elutriation. Four wool-scouring sludges from different processes were incinerated in the RFB. With 5% support methane, all sludges with a maximum moisture up to 70% as received could be successfully burned in the RFB at rotating speeds of 200 and 300 rpm. The combustion was found to be intense with a high ...

2000-09-01

367

Computer vision algorithms in DNA ploidy image analysis

Substitution of various rare earths R within the class of R2PdSi3 single crystals with hexagonal AlB2-type crystallographic structure reveals the systematic dependence of anisotropic magnetic properties governed by the interplay of crystal-electric field effects and magnetic two-ion interactions. Here we compare the floating zone (FZ) crystal growth with radiation heating of compounds with R = Tb, Tm, Pr, and Gd. The congruent melting behavior enabled moderate growth velocities of 3 to 5 mmh-1. The preferred growth directions are close to the basal plane of the hexagonal unit cell. The composition of the crystals, except of Tb2PdSi3, is slightly Pd-depleted with respect to the nominal composition 16.7 at.% Pd. Thin precipitates of RSi secondary phases were detected in the crystal matrix. Their phase fraction can be diminished by growth from Pd-rich melt compositions and annealing treatments. The compounds exhibit antiferromagnetic order below ...

2011-06-01

368

Clinical significance of changes of plasma endothelial vasoactive factors contents after treatment in patients with systemic sclerosis (SSc)

The high incidence and mortality rates of prostate cancer have stimulated research for prevention, early diagnosis and appropriate treatment. DNA ploidy status of tumour cells is an important parameter with diagnostic and prognostic significance. In the current study, DNA ploidy analysis was performed using image cytometry technique and digital image processing and analysis. Tissue samples from prostate patients were stained using the Feulgen method. Images were acquired using a digital imaging microscopy system consisting of an Olympus BX-50 microscope equipped with a color CCD camera. Segmentation of such images is not a trivial problem because of the uneven background, intensity variations within the nuclei and cell clustering. In this study specific algorithms were developed in Matlab based on the most prominent image segmentation approaches that emanate from the field of Mathematical Morphology, focusing on region-based watershed segmentation. First biomedical images were ...

2006-03-01

369

Removal of radioactive ions from nuclear waste solutions by electrodialysis

Objective: To investigate the relationship between endothelial vasoactive factors and development of systemic sclerosis (SSc). Methods: Blood circulating endothelial cell count (CEC, with density gradient precipitation method); plasma endothelin (ET), thromboxane B2 (TXB2 ), 6-keto-prostaglandin F1? concentrations (all above three with RIA); nitric oxide (NO) contents (with Griss method) and plasma intercellular adhesion molecule-1 (ICAM-1), p-selectin (P-S) contents (with ELISA) were measured in 52 patients with systemic sclerosis (SSc) both before and after treatment with prostaglandin E1 and 30 controls. Results: Plasma ET, TXB2, ICAM-1, P-S contents and CEC were significantly higher and plasma NO, 6-K-PGF1? contents were significantly lower in all the patients with SSc before treatment than those in the controls, After treatment, the patients with satisfactory responses (n=33) had the abnormal plasma values of these parameters greatly ...

2005-02-01

370

Patterns of ovarian morphology in polycystic ovary syndrome: a study utilising magnetic resonance imaging

Removal of radioactive ions was studied from low and medium level radioactive waste solutions by electrodialysis using ion exchange membranes. The test solutions contained "1"3"7Cs"+, "1"0"6Ru"3"+ or fission products (F.P.) as active ions and NaCl, Na_2SO_4 or Ca(NO_3)_2 as inactive coexisting salts. The decontamination factor of the active ions was in the order: "1"3"7Cs"+ (greater than 99%) > "9"0Sr"2"+ > F.P. > "1"0"6Ru"3"+. The dialysis time required to attain the saturation was the shortest for monovalent cations K"+, Cs"+ and Na"+, intermediate for divalent cation Sr"2"+, and the longest for trivalent cation Ru"3"+. The ratio of the decontamination factor of an active ion eta sub( a) to the desalination factor of an inactive ion eta sub( b) was nearly equal to unity for "2"4Na, "4"2K, "1"3"7Cs and "9"0Sr. On the other hand, the apparent selective permeability of an active ion (A"+) against Na"+ ion, T sub(Na"+) sup( a) was higher ...

371

Neutron-hole strengths and core coupling in /sup 87/Sr via the /sup 88/Sr("3He,#alpha#)/sup 87/Sr reaction

To evaluate and compare MRI-based ovarian morphology in groups of women with polycystic ovary syndrome (PCOS) and controls. All PCOS cases (n = 44) had oligo-amenorrhoea and hyperandrogenism irrespective of ovarian morphology, and fulfilled NIH/Rotterdam diagnostic criteria for PCOS. All control women (n = 40) had normal menses and normoandrogenaemia. All subjects were of white British/Irish origin and pre-menopausal. Group comparisons were based on independent-sample t tests. Polycystic ovarian morphology was defined by at least 12 follicles 2-9 mm in diameter and/or an ovarian volume greater than 10 cm{sup 3}. Ovarian morphology differed significantly in PCOS cases and controls (follicle number geometric mean [SD range] 18.6 [9.9, 35.0] vs 6.6 [3.1, 14.2], unadjusted P = 1.3 x 10{sup -16}; calculated ovarian volume 8.8 cm{sup 3} [5.0, 15.5] vs 5.1 cm{sup 3} [2.5, 10.3], unadjusted P = 3.0 x 10{sup -7}; peripheral follicle location in 55% vs ...

2010-05-15

372

Ion backscattering, channeling and nuclear reaction analysis study of passive films formed on FeCrNi and FeCrNiMo (100) single crystals

Neutron-hole states in /sup 87/Sr were studied by means of the /sup 88/Sr("3He,#alpha#)/sup 87/Sr reaction at 36 MeV. Angular distribution measurements were carried out from 3"0 to 41"0 (lab) and analyzed with the zero-range distorted-wave Born approximation method. Spectroscopic factors have been determined for about 50 discrete levels in /sup 87/Sr located below 6 MeV excitation energy and for the three lowest isobaric analog states 2p(3/2, 1f(5/2, and 2p(1/2 observed around 11 MeV. Many l = 1 and l = 3 discrete levels are observed in the 3--6 MeV excitation energy range. In addition, a large part of the 1f-2p strength is found to lie in the higher-lying continuum up to 13 MeV (about 10% and 40% for the l = 1 and 3 contributions, respectively). The distribution of the 1f-2p neutron-hole strength is compared to previous data on neighboring nuclei /sup 89/Zr and /sup 91/Mo. In addition, angular distributions for some low-lying high-spin states ...

373

Input deuteron states in Mo even isotopes

The compositions of passive films formed on Fe-17Fr-13Ni (at. %) and Fe-18.5Cr-14Ni-1.5Mo (100) single crystals have been determined and the structure of the alloy under the film has been investigated. The alloys were passivated in 0.05M H_2SO_4 at 250 mV/SHE for 30 min. The oxygen content was measured by nuclear microanalysis using the "1"6O(d,p) "1"7O* reaction. The oxygen content in the passive film is similar for the two alloys and equal to (12#+-#2) 10"1"5 O/cm"2. The cationic compositions of the passive films have been determined by "4He channeling at two incident beam energies: 0.8 and 2.0 MeV. For the two alloys studied, a total cation content of (5#+-#2)10"1"5 at/cm"2 is found in the passive films. The corresponding thickness is about 12 A. There is an excess of oxygen, which can be attributed to the presence of hydroxyls and sulfate. A strong chromium enrichment is found in the passive film formed on both alloys: chromium represents ...

1989-09-24

374

High mobility two-dimensional hole system in GaAs/AlGaAs quantum wells grown on (100) GaAs substrates

An attempt is taken to explain anomalies in "9"2Mo(d, n)"9"3Tc, "9"2Mo(d, #alpha#)"9"0Nb, "9"4Mo(d, n)"9"5Tc, "9"8Mo(d, n)"9"9Tc, "9"8Mo(d, p)"9"9Mo, "9"8Mo(d, #alpha#)"9"6Nb, "1"0"0Mo(d, p)"1"0"1Mo and "1"0"0Mo(d, n)"1"0"1Tc reactions with input states having a one-particle nature. Thin films saturated with molybdenum isotopes at the approximately 1 mgxcm"-"2 surface density are used as targets. The targets are irradiated by the extracted cyclotron beam. The deuteron energy is 5-12 MeV. The reaction cross sections are determined by the activation analysis method. Quasi-stationary levels of the nucleus-deuteron system are calculated. Weak anomalies revealing in a smooth (d, #alpha#) reaction cross section on sup(92, 98)Mo nuclei, which do not necessarily correlate with anomalies in the (d, n) and (d, p) channels, are observed. The ground states of the (d, #alpha#) reaction products "9"0Nb and "9"6Nb have (8"+) and (6"+) spins, respec,.ively, ...

375

Evaluation of 1-site and 5-site models of methane on its adsorption on graphite and in graphitic slit pores.

We report on the transport properties of a high mobility two-dimensional hole system (2DHS) confined in GaAs/AlGaAs quantum wells grown by molecular-beam epitaxy on the (100) surface of GaAs. The quantum wells are modulation doped with carbon utilizing a resistive filament source. At T=0.3 K and carrier density p=1x10"1"1 cm"-"2, a mobility of 10"6 cm"2/Vs is achieved. At fixed carrier density p=10"1"1 cm"-"2, the mobility is found to be a nonmonotonic function of the quantum well width. The mobility peaks at 10"6 cm"2/Vs for a 15-nm well and is reduced for both smaller and larger well widths for these (100) samples. The mobility anisotropy is found to be small. Mobility along [011] is approximately 20% higher than along the [011] direction. In addition, the low-temperature carrier density is found to have low sensitivity to light. The hole density increases by only #approx#10% after exposure to red light at T=4.2 K. In structures designed for ...

2005-04-18

376

Environmental and plant effects of sewage sludge application to forests and pastures

In this paper, we evaluate the performance of the 1- and 5-site models of methane on the description of adsorption on graphite surfaces and in graphitic slit pores. These models have been known to perform well in the description of the fluid-phase behavior and vapor-liquid equilibria. Their performance in adsorption is evaluated in this work for nonporous graphitized thermal carbon black, and simulation results are compared with the experimental data of Avgul and Kiselev (Chemistry and Physics of Carbon; Dekker: New York, 1970; Vol. 6, p 1). On this nonporous surface, it is found that these models perform as well on isotherms at various temperatures as they do on the experimental isosteric heat for adsorption on a graphite surface. They are then tested for their performance in predicting the adsorption isotherms in graphitic slit pores, in which we would like to explore the effect of confinement on the molecule packing. Pore widths of 10 and 20 ...

2005-10-20

377

Contribution of pulmonary emphysema to functional impairment in patients with severe chronic obstructive pulmonary disease. A high-resolution CT study

Digested sewage sludge was applied to pastures and tree plantations at 19 to 44 Mg/ha (dry weight) as part of a municipal sludge disposal program. The sludge had low concentrations of heavy metals and traces of /sup 137/Cs and /sup 60/Co. Monitoring of soils, soil solutions, and runoff indicated that N, P, heavy metals, and radionuclides were largely retained in the upper 15cm of the soil. Soil solutions had elevated NO/sub 3//sup /minus// concentrations often >100 mg/L, but no significant increases in groundwater NO/sub 3//sup /minus// were found during the first year. Runoff from active sites had elevated concentrations of NO/sub 3//sup /minus// (20--30 mg/L), soluble P (1 mg/L), BOD/sub 5/ (5--30 mg/L), and fecal coliform (up to 14,000 colonies per 100 ml), not unlike runoff from pastures with cattle. Enrichment of organic N (2 times), available (inorganic) N (5 to 10 times), and Bray-P in the upper soils persisted for several years ...

1989-01-01

378

Charged particle spectra: 140 MeV #alpha# particle bombardment of "2"7Al, "5"8Ni, "9"0Zr, "2"0"9Bi, and "2"3"2Th

The purpose of the paper is to investigate whether high-resolution CT (HRCT) can detect the subjects with massive emphysematous destruction in a group of patients with severe chronic obstructive pulmonary disease (COPD) and therefor be of help in selecting the candidates to surgical lung volume reduction. Have been examined 40 former smokers with severe COPD (FEV_1#<=#40% of the predicted value, with no major improvement after inhalation of bronchodilators). The emphysema extent score was significantly correlated with the hematocrit value and Tiffeneau index (p<2) in all the 40 patients. The severity of bronchial obstruction was the same in bronchitis and dyspnoeic patients. The subject with chronic bronchitis had milder emphysema (mean extent 35% versus 47% in the dyspnoeic subjects) and a higher frequency of bronchial involvement. A decrease in FEV_1 was significantly correlated with emphysema extent (p<1) in dyspnoeic, but not in ...

1999-01-01

379

Characteristics and formation mechanism of Permian Shanxi tight gas reservoir of Changbei gas field, Ordos Basin

Complete energy spectra and angular distributions of the light charged particles (A < or = 4) were measured for the bombardment of "2"7Al, "5"8Ni, "9"0Zr, "2"0"9Bi, and "2"3"2Th with 140 MeV #alpha# particles. The spectral shapes of a given emitted particle are very similar for all target nuclei except in the region of the evaporation peak. The slopes of the energy spectra in the forward direction become steeper as the mass of the observed particle decreases and vary very rapidly with angles. The experimental data can be characterized by compound nuclear evaporation processes at low energies, or at backward angles, and by direct reactions, nonequilibrium components and projectile breakup processes at high energies and forward angles. The breakup cross section for #alpha# particles is found to be appreciable. The total yield of light charged particles is approximately a factor approx. 2 to 3 larger than the total reaction cross section for "2"7Al, "5"8Ni, and "9"0Zr and is approx. ...

380

Cerenkov ring imaging and spectroscopy of charged KSTAR interactions at 11 GeV/c

This paper discussed the lithological characteristics of tight gas reservoirs, including the diagenetic characteristics, diagenetic environment and diagenetic sequence. The link between porosity, the sedimentary environment, lithology, diagenesis and basin tectonics was examined in order to determine how tight reservoirs were formed. The study focused on the Changbei gas field located in Yishan Slope of the Ordos Basin in China. The main pay zone reservoir is the Upper Paleozoic Lower Permian Shanxi sandstone which lies at a depth of 2700-2950 m. This low porosity, low permeability tight gas reservoir was deposited in a coal bearing acid environment which controlled the diagenesis sequence. The early carbonate cement was not well developed because the original pore water was acidic with non saturated calcium carbonate. However, compaction has significantly reduced the original pore and pore volume. The acidic environment caused large amounts of secondary quartz cementation to fill the ...

2010-07-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

381

Analysis and design of an ultra-high-temperature, hydrogen-fueled MHD generator as an open cycle power supply

The physics and technology of this new Cerenkov detector are discussed, including materials studies, construction techniques, and resolution measurements. Sources of resolution error are individually identified and measured where possible. The results of all studied indicate that the measurement resolution is understood. This work has led to the adoption of a large scale ring imaging detector as part of a new high energy physics spectrometer, the SLD, at the Stanford Linear Accelerator Center. Results from an amplitude analysis of strange meson final states in K/sup /minus//p ..-->.. /ovr K/sub 0//..pi../sup /minus//p interactions are presented. The data derive from a 4 event/nb exposure of the LASS (large Aperture Superconducting Solenoid) spectrometer to an 11 GeV/c K/sup /minus// beam. The data sample consists of /approximately/100,000 vents distributed over the Dalitz plot of the channel. The process is observed to be dominated by the production and decay of natural spin-parity ...

1988-11-01

382

An ultraviolet-inducible adenosine-adenosine cross-link reflects the catalytic structure of the Tetrahymena ribozyme

The theoretical analysis of a partially-ionized hydrogen gas flow (gas temperatures of approximately 10,000 to 20,000 K) through a particular class of magnetohydrodynamic (MHD) generators and the preliminary design of these MHD generators as open cycle, electric power supplies are performed. Analysis of the gas flow through these ultra-high temperature MHD generators requires a coupled gas dynamics/radiative heat transfer solution. Gas dynamics are modeled by a set of quasi-one-dimensional, nonlinear differential equations which account for friction, convective and radiative heat transfer and the interaction between the ionized gas and applied magnetic field. Radiative heat transfer is modeled using non-gray, absorbing-emitting two- and three-dimensional P-1 approximations which permit an arbitrary variation of the spectral absorption coefficient with frequency. Gas dynamics and radiative heat transfer are coupled through the energy equation, ...

1990-01-01

383

A study of the photoionisation dynamics of chloromethane and iodomethane

When a shortened enzymatic version of the Tetrahymena self-splicing intervening sequence (IVS) RNA is placed under catalytic conditions and irradiated at 254 nm, a covalent cross-link forms with high efficiency. The position of the cross-link was mapped by using three independent methods: RNase H digestion, primer extension with reverse transcriptase, and partial hydrolysis of end-labeled RNA. The cross-link is chemically unusual in that it joins two adenosines, A57 and A95. Formation of this cross-link depends upon the identity and concentration of divalent cations present and upon heat-cool renaturation of the IVS in a manner that parallels conditions required for optimal catalytic activity. Furthermore, cross-linking requires the presence of sequences within the core structure, which is conserved among group I intervening sequences and necessary for catalytic activity. Together these correlations suggest that a common folded structure permits cross-linking and catalytic activity. ...

1990-06-12

384

A study of relative regional cerebral blood flow using N-isopropyl-p-["1"2"5I]-iodoamphetamine ("1"2"5I-IMP) in carbon monoxide exposed rats

Angle resolved valence shell photoelectron spectra of chloromethane and iodomethane have been recorded using synchrotron radiation in the photon energy range 14-120eV. These have allowed photoelectron angular distributions and branching ratios to be determined not only for the main bands associated with the single-hole states but also for the satellite structure due to many-electron effects. The continuum multiple scattering approach has been used to calculate photoelectron asymmetry parameters and branching ratios for the valence orbitals of CH_3Cl and CH_3I, and also for the I 4d subshell. A comparison between the experimental data and the theoretical predictions has enabled the influence of Cooper minima, shape resonances and intershell coupling to be assessed. The asymmetry parameters and branching ratio for the spin-orbit split components of the CH_3I"+X-bar "2E state have been measured and exhibit a spectral behaviour almost identical to that of the corresponding data for the Xe ...

2006-08-01

385

Atomic interactions between plutonium and helium.

The influence of carbon monoxide (CO) exposure on regional cerebral blood flow (r-CBF) in rat brain was studied using autoradiography and "1"2"5I-IMP. Fuji computed radiography (FCR) was used to obtain improved autoradiograms in this study. R-CBF was determined in a relative measure by calculating hippocampus/cortex and putamen/cortex ratios of RI accumulation from the autoradiogram using a densitometer. Comparison of autoradiograms with pathological findings in the area of the hippocampus and putamen yield the following results. In the animals that were exposed to 6400 ppm or 10000 ppm of CO for 30 minutes, and then were followed up for 2 weeks without further exposure, r-CBF was decreased but no pathological changes occurred. In the animals that were exposed to 6400 ppm or 10000 ppm of CO, and then were followed up for 4 weeks without further exposure, pathological changes appeared. In animals exposed to 3200 ppm of CO, the r-CBF tended to recover after 4 weeks. Furthermore, ...

386

Structures and luminescent properties of new uranyl-based hybrid materials

An essential issue in gallium (Ga)-stabilized fcc-phase plutonium ({delta}-Pu) is the formation of helium (He) voids and bubbles emanating from the radiolytic decay of the Pu. The rate of formation of He voids and bubbles is related to the He-defect formation energies and their associated migration barriers. The size and shape distributions of the bubbles are coupled to these critical migration processes. The values of the defect formation energies, internal pressure, and migration barriers can be estimated from atomistic calculations. Complicating this picture is the destruction of He-filled voids and bubbles by subsequent radiolytic decay events. The present study concerns the construction of the necessary potential energy surfaces for the Pu-He and He-He interactions within the modified embedded atom method (MEAM). Once fully tested, the potentials will be used to estimate the He-defect formation energies and barriers to the migration of these defects for both interstitial and ...

2002-01-01

387

"Hyperfine Splitting, Isotope Shift, and Level Energy of the 3S States of Li-6, Li-7."

Six uranyl coordination compounds, UO_2(OH)(PYCA) (1), UO_2(PYCA)_2(H_2O).2H_2O (2), UO_2(PIC)_2 (3), UO_2(H_2O)_2(NIC)_2 (4), UO_2(OH)(HINIC)(INIC) (5), and UO_2(PYTAC)_2(H_2O)_2 (6) were grown as single crystals via hydrothermal synthesis (PYCA - pyrazine-2-carboxylate, PIC - picolinate, NIC - nicotinate, INIC - iso-nicotinate, and PYTAC - 2-(pyridin-4-yl)thiazole-5-carboxylate) to study their optical properties. All six compounds have been identified via single crystal X-ray diffraction and fully characterized via powder X-ray diffraction, infrared spectroscopy, UV-Vis spectroscopy, and fluorescence spectroscopy. Three of the complexes, 1, 3, and 6, represent new structures, and their synthesis and structural characterization is detailed within. The structures of 2, 4, and 5 have previously been reported in the literature. Coordination polymer 1 crystallizes in the orthorhombic space group Pca21 (a = 13.5476(5) Angstroms, b = 6.6047(2) Angstroms, c = 8.3458(3) Angstroms), and forms ...

2011-06-01

388

The ternary system cerium-palladium-silicon

High-precision laser spectroscopy on lithium isotopes is of fundamental interest, experimentally as well as theoretically. The lithium atom has long served as a test system for the calculation of various atomic properties in few-electron atoms and significant advances have been made in the last decade[1-3]. Recently, calculations of transition energies for the 22S1/2 -> 32S1/2 and the 22S1/2 -> 22P1/2, 3/2 transitions and of the mass-dependant isotope shift (IS) in these transitions have been reported with a relative accuracy of better than 1 X 10-7 and 5 x 10-6, respectively[4, 5]. These calculations are the foundation for experimental efforts, currently underway at GSI Darmstadt, Germany, to determine the root-mean-square (rms) charge radius of the unstable lithium isotopes[6, 7]. The basic principle is that if all mass-dependent contributions to the IS can be calculated with sufficient accuracy, the residual discrepancy between ...

2003-07-25

389

Model to simulate the interaction between boron carbide and steam or air at high temperature

Phase relations in the ternary system Ce-Pd-Si have been established for the isothermal section at 800 deg. C based on X-ray powder diffraction and EMPA techniques on about 130 alloys, which were prepared by arc-melting under argon or powder reaction sintering. Eighteen ternary compounds have been observed to participate in the phase equilibria at 800 deg. C. Atom order was determined by direct methods from X-ray single-crystal counter data for the crystal structures of #tau#_8-Ce_3Pd_4Si_4 (U_3Ni_4Si_4-type, Immm; a=0.41618(1), b=0.42640(1), c=2.45744(7) nm), #tau#_1_6-Ce_2Pd_1_4Si (own structure type, P4/nmm; a=0.88832(2), c=0.69600(2) nm) and also for #tau#_1_8-CePd_1_-_xSi_x (x=0.07; FeB-type, Pnma; a=0.74422(5), b=0.45548(3), c=0.58569(4) nm). Rietveld refinements established the atom arrangement in the structures of #tau#_5-Ce_3PdSi_3 (Ba_3Al_2Ge_2-type, Immm; a=0.41207(1), b=0.43026(1), c=1.84069(4) nm) and #tau#_1_3-Ce_3_-_xPd_2_0_+_xSi_6 (0#<=#x#<=#1, Co_2_0Al_3B_6-type, ...

2009-09-01

390

Correlation between the microstructure and the physical properties of HTSC single crystals and films. Final report; Korrelation zwischen der Realstruktur und den physikalischen Eigenschaften von HTSL-Einkristallen und -Schichten. Abschlussbericht

The oxidation of boron carbide in steam or air was recently extensively studied especially in Forschungszentrum Karlsruhe, Institut fuer Materialforschung. An important data set is available for the interaction modelling. An oxygen diffusion model through the superficial liquid boron oxide formed on the boron carbide external surface associated to a superficial reaction between the liquid boron oxide and steam is proposed to simulate the experimental kinetics from BOX rig and thermogravimetric tests on the interaction between steam and boron carbide at a temperature range 800 C to 1400 C. The oxygen diffusion model will be also useful to simulate interaction between boron carbide and Ar+O2 (air simulation) atmosphere when the steam pressure becomes zero. From the analysis of BOX rig experimental kinetics of non-condensable (H2, CO2, CO and CH4) gases we propose an oxygen diffusion model through the liquid boron oxide and a ''steam/liquid boron ...

2005-03-01

391

Review of JT-60U experimental results from February to October, 1999

1. In order to carry out isothermic crystal growth experiments of YBCO the 123 primary crystallization field was determined by means of phase diagram investigations and crystal growth experiments at different oxygen partial pressure. 2. YBCO single crystals of high crystallographic perfection were grown and conclusions on the flux pinning mechanism were drawn. 3. By means of Liquid Phase Epitaxy (LPE) single crystalline (Tc{approx}90 K; {Delta}T{<=}0.5 K) c- and a,b- YBCO fils have been prepared on NdGaO{sub 3} and LaGaO{sub 3} substrates. The films were characterized structurally and magnetically. 4. Our fist melt textured YBCO ``single crystals`` possess intracrystalline critical current densities >10{sup 4} A/cm{sup 2} at B{<=}2T. The irreversibility inductions are {<=}6 T at 77 K. A simple demonstrator was constructed together with the IFW Dresden and a growth model was developed. 5. Using above all torque magnetometer ...

1993-06-01

392

WLUP3.0, 69 and 172 Group Cross Section Libraries for WIMS

In 1999, the plasma parameters of reversed shear (RS) plasmas had been extended in 1) DT-equivalent fusion power gain Q_D_T"e"q - 0.5 (n_D(0)#tau#_ET_i(0) - 4x10"2"0 m"-"3#centre dot#keV#centre dot#s) for 0.8 s and 2) full non-inductive current drive with 80% of the bootstrap current fraction. Physics of the internal transport barriers (ITBs) in RS plasmas, including the energy transport and the formation of ITB, were extensively studied. A nearly full current drive (92% non-inductively) was obtained with negative ion based neutral beam (NNB) injection (360 keV, 3.4 MW) in a high #beta#_p H-mode plasma (I_p=1.5 MA, B_T=3.7 T, q_9_5=4.2) with high plasma performance (#beta#_N=2.4 and H_8_9=2.56). Rise in the central electron temperature (T_e - 9 keV) resulted in the current drive efficiency #eta#_C_D of NNB reached 1.3x10"1"9 A/W/m"2, the highest for the neutral beam current drive. As for the H-mode plasmas, decrease in the pedestal ion ...

1994-06-01

393

A micromachined high pressure stable mass flow sensor for common-rail injection systems; Ein mikromechanisch gefertigter hochdruckstabiler Massenflusssensor fuer Common-Rail(CR)-Einspritzsysteme

Description or function: WLUP contains validated WIMS-D formatted cross section libraries in 69 and 172 energy group structures for nuclear reactor calculations. Materials from recently released evaluated nuclear data libraries are included. The NJOY nuclear data processing system was applied for generating the cross section files following the models and conventions built into the WIMS-D lattice code. The relevant features for the WIMS users are: - Energy group structures: 69 and 172 energy groups. - List of materials: WIMS ID, general information, source of data. - Cross sections: 69 and 172 group plots. - Resonance data: WIMS ID, temperature, background cross sections. - Goldstein-Cohen factors: Goldstein-Cohen lambda values. - Thermal scattering data: thermal scattering laws and P1 matrixes. - Fission spectrum: fission spectrum data. - Burnup data: burnup chains. - Fission product yields: fission yield tables. - Pseudo lumped fission ...

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