WorldWideScience
1

Effect of forced swimming stress on in-vivo fertilization capacity of rat and subsequent offspring quality  

UK PubMed Central (United Kingdom)

AIMS:This study aimed to determine the effect of 50 days of forced swimming stress on fertilization capacity of rat and subsequent offspring quality.SETTING...Full Text Available

2010-01-01

2

Moderate Caloric Restriction during Gestation in Rats Alters Adipose Tissue Sympathetic Innervation and Later Adiposity in Offspring  

UK PubMed Central (United Kingdom)

Maternal prenatal undernutrition predisposes offspring to higher adiposity in adulthood. Mechanisms involved in these programming effects, apart from those described in central nervous system development,...Full Text Available

3

Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts  

UK PubMed Central (United Kingdom)

Although genetically identical for autosomal Chrs (Chr), male and female preimplantation embryos could display sex-specific transcriptional regulation. To illustrate sex-specific differences at the...Full Text Available

2010-02-23

4

An animal model of social instability stress in adolescence and risk for drugs of abuse  

British Library Electronic Table of Contents (United Kingdom)

There is increasing evidence that adolescence, like early life, is a sensitive period in which ongoing brain development can be influenced by environmental factors. This review describes our use of social instability as a model of mild adolescent social stress, its effects on social interactions and on hypothalamic?pituitary?adrenal function over the course of the procedure and in response to new stressors. The effects of social instability are sex-specific, with qualitative differences between the sexes on HPA function over the course of the stressor procedure, and with greater effects in males on behaviour observed during the social instability and greater effects in females on behavioural responses to drugs of abuse into adulthood, long after the stress exposure. The results from invest...

2010-01-01

5

Subjective effects to cannabis are associated with use, abuse and dependence after adjusting for genetic and environmental influences  

British Library Electronic Table of Contents (United Kingdom)

Background Previous reports in adults have suggested that the effects experienced after cannabis use can be described in terms of positive and negative subtypes that are heritable and are associated with abuse and dependence. This study extends existing research by inclusion of adolescents and young adults in an offspring of twins design which makes it possible to take into account genetic and environmental risks for substance use disorder. Methods Data were collected from 725 twin members of the Vietnam Era Twin Registry, 839 of their 12-32 year old biological offspring and 427 mothers. Offspring who had ever used cannabis (n=464) were asked the degree to which they typically experienced 13 subjective effects shortly after using cannabis. Latent class analysis (LCA) was used to derive sub...

2009-01-01

6

Sex-specific influence of exposure to bisphenol-A between adolescence and young adulthood on mouse behaviors  

British Library Electronic Table of Contents (United Kingdom)

Bisphenol-A (BPA) is one of the most common environmental endocrine disrupters and has a wide range of effects on central nervous system. Adolescence is another important developmental period besides the early critical prenatal and neonatal periods. In the present study, we exposed mice to BPA (40, 400 mg/kg/d) between adolescence and young adulthood for 8 weeks and investigated its effects on the non-reproductive behaviors. In open field tests, rearing and grooming sex differences were abolished by BPA exposure. In the elevated plus maze test, the number of open arm entries, the time spent in open arms, and the number of unprotected head dips in the center area were reduced in males but increased in females by BPA at 40 or 400 mg/kg/d, thus eliminating or reversing sex differences in thes...

2011-01-01

7

Body size and predatory performance in wolves: is bigger better?  

British Library Electronic Table of Contents (United Kingdom)

Summary Large body size hinders locomotor performance in ways that may lead to trade-offs in predator foraging ability that limit the net predatory benefit of larger size. For example, size-related improvements in handling prey may come at the expense of pursuing prey and thus negate any enhancement in overall predatory performance due to increasing size. This hypothesis was tested with longitudinal data from repeated observations of 94 individually known wolves (Canis lupus) hunting elk (Cervus elaphus) in Yellowstone National Park, USA. Wolf size was estimated from an individually based sex-specific growth model derived from body mass measurements of 304 wolves. Larger size granted individual wolves a net predatory advantage despite substantial variation in its effect on the performance ...

2009-01-01

8

The Effects of Aspirin-Like Drugs on the Nutritional Status of Pregnant Rats and Offspring  

UK PubMed Central (United Kingdom)

Previous studies have shown that salicylates and protein-calorie malnutrition independently compromise maturation and growth of infants. In the present study, pregnant rats were fed normal-and low-protein...Full Text Available

1988-05-01

9

Hybrid incompatibilities in the parasitic wasp genus Nasonia: negative effects of hemizygosity and the identification of transmission ratio distortion loci.  

Science.gov (United States)

The occurrence of hybrid incompatibilities forms an important stage during the evolution of reproductive isolation. In early stages of speciation, males and females often respond differently to hybridization. Haldane's rule states that the heterogametic sex suffers more from hybridization than the homogametic sex. Although haplodiploid reproduction (haploid males, diploid females) does not involve sex chromosomes, sex-specific incompatibilities are predicted to be prevalent in haplodiploid species. Here, we evaluate the effect of sex/ploidy level on hybrid incompatibilities and locate genomic regions that cause increased mortality rates in hybrid males of the haplodiploid wasps Nasonia vitripennis and Nasonia longicornis. Our data show that diploid F(1) hybrid females suffer less from hybridization than haploid F(2) hybrid males. The latter not only suffer from an increased mortality rate, but also from behavioural and spermatogenic sterility. ...

2011-08-31

11

Chronic maternal stress affects growth, behaviour and hypothalamo?pituitary?adrenal function in juvenile offspring  

British Library Electronic Table of Contents (United Kingdom)

Maternal stress during pregnancy, particularly that combined with low socioeconomic status (SES), has been linked to an increased risk for impaired behavioural and emotional development and affective disorders in children. In animal models, acute periods of prenatal stress have profound effects on hypothalamo-pituitary-adrenal (HPA) function and behaviour. However, few studies have determined the impact of chronic exposure to stress in animal models. The objective of this study was to determine the effects of chronic maternal stress (CMS) during the 2nd half of pregnancy and nursing on growth, locomotor behaviour and HPA axis function in juvenile guinea pig offspring. Pregnant guinea pigs were exposed to a random combination of variable stressors every other day over the 2nd half of gestat...

2008-01-01

12

Transgenerational Effects of Di (2-Ethylhexyl) Phthalate in the Male CRL:CD(SD) Rat: Added Value of Assessing Multiple Offspring per Litter  

UK PubMed Central (United Kingdom)

In the rat, some phthalates alter sexual differentiation at relatively low dosage levels by altering fetal Leydig cell development and hormone synthesis, thereby inducing abnormalities of the testis,...Full Text Available

2009-08-01

13

Trans-generational radiation-induced chromosomal instability in the female enhances the action of chemical mutagens  

Energy Technology Data Exchange (ETDEWEB)

Genomic instability can be produced by ionising radiation, so-called radiation-induced genomic instability, and chemical mutagens. Radiation-induced genomic instability occurs in both germinal and somatic cells and also in the offspring of irradiated individuals, and it is characterised by genetic changes including chromosomal rearrangements. The majority of studies of trans-generational, radiation-induced genomic instability have been described in the male germ line, whereas the authors who have chosen the female as a model are scarce. The aim of this work is to find out the radiation-induced effects in the foetal offspring of X-ray-treated female rats and, at the same time, the possible impact of this radiation-induced genomic instability on the action of a chemical mutagen. In order to achieve both goals, the quantity and quality of chromosomal damage were analysed. In order to detect trans-generational genomic ...

2008-04-02

14

The effects of short term and chronic exposure to tritiated drinking water on pre- and postnatal brain development  

International Nuclear Information System (INIS)

Ingestion of HTO during oocyte maturation and continued during pre-implantation time was found to depress decidual response. At birth these offspring also showed a decrease in brain cell number. When HTO was given during pregnancy only, the offspring at birth showed a similar deficit in brain cell number. Even so, we could not demonstrate a gross deficit in oocyte maturation when HTO was ingested during sexual maturity only; however, when further continued during pregnancy, the measured newborn parameters were most severely affected. In this group, cell-multiplication in the cerebrum was severely decreased, protein synthesis was decreased, and somatic growth was also highly significantly decreased. These experiments indicate that even a short-term exposure to HTO during early pregnancy (pre-implantation) alters normal development to such an extent that it is still observable at birth. During embryonic development, HTO affected the rate of ...

1980-11-26

15

Adjustment of sperm allocation under high risk of sperm competition across taxa: a meta-analysis  

British Library Electronic Table of Contents (United Kingdom)

Abstract Sperm competition theory predicts that under high risk of sperm competition, males will increase the number of sperm that they allocate to a female. This prediction has been supported by some experimental studies but not by others. Here, I conducted a meta-analysis to determine whether the increase in sperm allocation under high risk of sperm competition is a generalized response across taxa. I collected data from 39 studies and 37 species. Across taxa, males under a high risk of sperm competition respond by increasing their sperm allocation (mean effect size-=-0.32). Number of offspring did not explain a significant portion of the variation in effect sizes. A traditional meta-analysis (i.e. without phylogenetic information) described the variation among effect sizes better than a...

2011-01-01

16

Maternal Overweight Programs Insulin and Adiponectin Signaling in the Offspring  

UK PubMed Central (United Kingdom)

Gestational exposure to maternal overweight (OW) influences the risk of obesity in adult life. Male offspring from OW dams gain greater body weight and fat mass and develop insulin resistance when fed...Full Text Available

2010-06-01

17

Maternal Obesity Induced by Diet in Rats Permanently Influences Central Processes Regulating Food Intake in Offspring  

UK PubMed Central (United Kingdom)

Hypothalamic systems which regulate appetite may be permanently modified during early development. We have previously reported hyperphagia and increased adiposity in the adult offspring of rodents fed...Full Text Available

18

Blockade of androgen receptors is sufficient to alter the sexual differentiation of the substantia nigra pars reticulata seizure-controlling network  

UK PubMed Central (United Kingdom)

The substantia nigra pars reticulata (SNR) controls seizures in a sex-specific manner. At postnatal day 15 (P15), SNR infusion of GABAA receptor agonist muscimol have proconvulsant...Full Text Available

2008-03-01

19

The spoIIE homolog of Epulopiscium sp. type B is expressed early in intracellular offspring development.  

Science.gov (United States)

Epulopiscium sp. type B is an enormous intestinal symbiont of the surgeonfish Naso tonganus. Intracellular offspring production in Epulopiscium shares features with endospore formation. Here, we characterize the spoIIE homolog in Epulopiscium. The timing of spoIIE gene expression and presence of interacting partners suggest that the activation of ?(F) occurs early in Epulopiscium offspring development. PMID:21398534

2011-03-11

20

Neurochemical deficits in the cerebellar vermis in child offspring of parents with bipolar disorder  

British Library Electronic Table of Contents (United Kingdom)

Singh MK, Spielman D, Libby A, Adams E, Acquaye T, Howe M, Kelley R, Reiss A, Chang KD. Neurochemical deficits in the cerebellar vermis in child offspring of parents with bipolar disorder.-Bipolar Disord 2011: 13: 189-197. 2011 The Authors.-Journal compilation 2011 John Wiley & Sons A/S. Objectives:- We aimed to compare concentrations of N-acetyl aspartate, myo-inositol, and other neurometabolites in the cerebellar vermis of offspring at risk for bipolar disorder (BD) and healthy controls to examine whether changes in these neuronal metabolite concentrations occur in at-risk offspring prior to the onset of mania. Methods:- A total of 22 children and adolescents aged 9-17-years with a familial risk for bipolar I or II disorder [at-risk offspring with non-bipolar I disorder mood symptoms (AR...

2011-01-01

21

Maternal anesthesia via isoflurane or ether differentially affects pre-and postnatal behavior in rat offspring  

British Library Electronic Table of Contents (United Kingdom)

Our understanding of prenatal behavior has been significantly advanced by techniques for direct observation and manipulation of unanesthetized, behaving rodent fetuses with intact umbilical connections to the mother. These techniques involve brief administration of an inhalant anesthesic, enabling spinal transection of the rat or mouse dam, after which procedures can continue with unanesthetized dams and fetuses. Because anesthetics administered to the mother can cross the placental barrier, it is possible that fetuses are anesthetized to varying degrees. We compared in perinatal rats the effects of prenatal maternal exposure to two inhalant anesthetics: ether and isoflurane. Fewer spontaneous fetal movements and first postpartum nipple attachments were observed following maternal exposure...

2007-01-01

22

Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats  

International Nuclear Information System (INIS)

Endocrine disrupting chemicals can induce malformations and impairment of reproductive function in experimental animals and may have similar effects in humans. Recently, the environmental obesogen hypothesis was proposed, suggesting that environmental chemicals contribute to the development of obesity and insulin resistance. These effects could be related to chemical interaction with nuclear receptors such as the peroxisome proliferator activated receptors (PPARs). As several testosterone-reducing drugs are PPAR activators, we aimed to examine whether four PPAR agonists were able to affect fetal testosterone production and masculinization of rats. Additionally, we wished to examine whether these chemicals affected fetal plasma levels of insulin and leptin, which play important roles in the developmental programming of the metabolic system. Pregnant Wistar rats were exposed from gestation day (GD) 7-21 to diisobutyl phthalate (DiBP), ...

2008-09-04

23

Nutrition and Physical Activity in Aging, Obesity, and Cancer  

British Library Electronic Table of Contents (United Kingdom)

The liver is a primary target of growth hormone (GH). GH signals are mediated by the transcription factor signal transducer and activator of transcription 5 (STAT5). Here, we focus on recent discoveries about the role of GH-STAT5 signaling in hepatic physiology and pathophysiology. We discuss roles of the GH-STAT5 axis in body growth, lipid metabolism, and the cell cycle pertaining to hepatosteatosis, fibrosis, and hepatocellular carcinoma. Finally, we discuss recent discoveries about the role of GH-STAT5 in sex-specific gene expression and bile acid, steroid, and drug metabolism.

2011-01-01

24

Glucose Intolerance and Cardiometabolic Risk in Adolescents Exposed to Maternal Gestational Diabetes  

UK PubMed Central (United Kingdom)

OBJECTIVEAdolescent offspring of women with a history of gestational diabetes (GD) were evaluated for their cardiometabolic risks at a mean age of 15 years.RESEARCH...Full Text Available

2010-06-01

25

Scaling of offspring number and mass to plant and animal size: model and meta-analysis  

UK PubMed Central (United Kingdom)

The scaling of reproductive parameters to body size is important for understanding ecological and evolutionary patterns. Here, we derived allometric relationships for the number and mass of seeds, eggs...Full Text Available

2008-04-01

26

Rapid Onset of Maternal Vocal Recognition in a Colonially Breeding Mammal, the Australian Sea Lion  

UK PubMed Central (United Kingdom)

BackgroundIn many gregarious mammals, mothers and offspring have developed the abilities to recognise each other using acoustic signals. Such capacity may develop at different rates...Full Text Available

27

Polyandry increases offspring viability and mother productivity but does not decrease mother survival in Drosophila pseudoobscura  

UK PubMed Central (United Kingdom)

Polyandrous mating is common, but the benefits for females of polyandry remain controversial. To test whether mating with multiple males affects female fitness, we compared lifetime components of fitness...Full Text Available

2010-08-03

28

Geographical variation in relationships between parental body size and offspring phenotype at birth  

UK PubMed Central (United Kingdom)

BackgroundSize and body proportions at birth are partly determined by maternal body composition, but most studies of mother-baby relationships have only considered...Full Text Available

2006-01-01

29

Investigation of genomic instability by assay of DNA fingerprint from the offspring of male mice exposed to chronic low-level #gamma#-radiation  

International Nuclear Information System (INIS)

By polymerase chain reaction with arbitrary primer (AP-PCR), the possibility of transmission of genome instability to somatic cells of the offspring (F_1 generation) from male parents of mice exposed to chronic low-dose #gamma#-radiation was studied. Male mice 15 days after exposure to 10-50 cGy were mated with unirradiated females. Biopsies were taken from tale tips of two month-old mice progeny for DNA separation. Primer in the AP-PCR was 20-mer oligonucleotide flanking the micro-satellite locus Atplb2 on chromosome 11 of the mouse. Comparative analysis of individual fingerprints of AP-PCR products on DNA-templates from the offspring of irradiated and unirradiated male mice revealed an increased variability of micro-satellite-associated sequences in the genome of the offspring of males exposed to 25 and 50 cGy. DNA-fingerprints of the offspring of male mice exposed to chronic irradiation doses 10 and ...

2000-11-20

30

Decreased duration of pentobarbital-induced narcosis in immature and adult female rats prenatally exposed to cimetidine  

Energy Technology Data Exchange (ETDEWEB)

The effect of prenatal cimetidine exposure (PreCM) on the duration of pentobarbital-induced narcosis (DPN) was assessed in immature (14- and 28-day old) and adult (50-60-day old) male and female rats. PreCM exposure was accomplished by treating mothers with cimetidine (CM) (20 mg/kg, ip) daily for the last two days of gestation and then (0.01% in drinking water) throughout lactation. Pregnant mothers of untreated offspring (Con) received saline. PreCM decreased DPN to 505 +/- 33 min (from 611 +/- 23 min in Con) and 393 +/- 190 min (from 686 +/- 44 min in Con) in 14-day old male and female rats, respectively. Similarly, PreCM decreased DPN to 88 +/- 15 min (from 134 +/- 3 min in Con) and 102 +/- 19 min (from 171 +/- 44 min in Con) in 28-day old male and female rats, respectively. At 21 days, PreCM did not alter DPN in either sex. At 50-60 days, however, it decreased DPN to 144 +/- 41 min (from 238 +/- 7 min in Con) in females but had no ...

1986-03-01

31

Effects of chronic ingestion of tritiated water on prenatal brain development  

International Nuclear Information System (INIS)

In view of the anticipated increased use of atomic energy in industry, the possible long-term effects of chronic radiation exposure were studied in five generations of rats. Female rats (F_0) were given tritiated drinking water ("3HOH;3#mu#Ci/ml) from adolescence (60 days) until and throughout pregnancy. A separate study showed that the maximum radioactivity in the urine is reached in 30 days, and in the blood in 42 days. In the newborns, the highest specific activity was in the nucleic acid fraction, but total radioactivity was mainly due to the water (body fluids) compartment. No signs of radiation illness or increase in cataract formation in the mothers were observed. The food and water intake and body weight changes before pregnancy were normal. The course and the outcome of pregnancy were also normal. However, 60% of the newborns (F_1) exhibited hematomas, edemas, and subdural hemorrhages, which disappeared at 30 days of age. Bollod analysis of the F_1 ...

32

Cytogenetic effects of protracted gamma exposures from conception of male mice  

Energy Technology Data Exchange (ETDEWEB)

In order to gain an overall picture of the genetic effects of an increased level of background radiation it is necessary to study the results of protracted exposures to embryonic and immature germ-cell stages as well as to stages found in the mature organism. For this purpose, litters produced by female mice, kept in a 10 or 20 rad/day /sup 60/Co ..gamma..-irradiation field, were kept in the same fields from conception until about 60 days later, having absorbed doses of 526 and 1078 rad respectively. Tests on exposed female offspring showed them to be sterile. Eight weeks after removal from the gamma field, mean testis masses of males in the 20 rad/day series were only half normal but those receiving 10 rad/day were little affected. Frequencies of translocations in spermatocytes at diakinesis/metaphase I were only slightly increased in the exposed series, differences not being significant. Estimated rates of translocation induction were around ...

1982-01-01

33

Association of attention-deficit disorder and the dopamine transporter gene  

Energy Technology Data Exchange (ETDEWEB)

Attention-deficit hyperactivity disorder (ADHD) has been shown to be familial and heritable, in previous studies. As with most psychiatric disorders, examination of pedigrees has not revealed a consistent Mendelian mode of transmission. The response of ADHD patients to medications that inhibit the dopamine transporter, including methylphenidate, amphetamine, pemoline, and bupropion, led us to consider the dopamine transporter as a primary candidate gene for ADHD. To avoid effects of population stratification and to avoid the problem of classification of relatives with other psychiatric disorders as affected or unaffected, we used the haplotype-based haplotype relative risk (HHRR) method to test for association between a VNTR polymorphism at the dopamine transporter locus (DAT1) and DSM-III-R-diagnosed ADHD (N = 49) and undifferentiated attention-deficit disorder (UADD) (N = 8) in trios composed of father, mother, and affected offspring. HHRR ...

1995-04-01

34

Parental subfecundity and risk of decreased semen quality in the male offspring: a follow-up study.  

Science.gov (United States)

A few studies have found poor semen quality in sons whose mothers have received fertility treatment, but it is unknown whether the poor semen quality is related to the infertility treatment or to infertility per se, for example, whether it is caused by hereditable factors. Using data from a population-based, Danish follow-up study conducted in 2005-2006, the authors of the present study examined whether sons of subfertile couples who had not received fertility treatment had poorer semen quality than sons of fertile couples. Among the 311 participants, an inverse association between parental waiting time to pregnancy and both semen volume and total sperm count was observed (p trend = 0.04 and p trend = 0.046, respectively). Semen volume in sons of subfertile parents (pregnant after > or =1 years) was 19% lower in comparison with that in sons of parents whose waiting time to pregnancy was 0-6 months (p = 0.02). Additionally, sperm concentration and percentage of morphologically normal ...

2008-04-11

35

Parental subfecundity and risk of decreased semen quality in the male offspring: a follow-up study  

DEFF Research Database (Denmark)

A few studies have found poor semen quality in sons whose mothers have received fertility treatment, but it is unknown whether the poor semen quality is related to the infertility treatment or to infertility per se, for example, whether it is caused by hereditable factors. Using data from a population-based, Danish follow-up study conducted in 2005-2006, the authors of the present study examined whether sons of subfertile couples who had not received fertility treatment had poorer semen quality than sons of fertile couples. Among the 311 participants, an inverse association between parental waiting time to pregnancy and both semen volume and total sperm count was observed (p trend = 0.04 and p trend = 0.046, respectively). Semen volume in sons of subfertile parents (pregnant after > or =1 years) was 19% lower in comparison with that in sons ofparents whose waiting time to pregnancy was 0-6 months (p = 0.02). Additionally, sperm concentration and percentage of morphologically normal ...

2008-01-01

36

Effect of temperature on the development of Steinernema carpocapsae and Steinernema feltiae (Nematoda: Rhabditida) in liquid culture.  

Science.gov (United States)

For commercial use of the entomopathogenic nematodes Steinernema carpocapsae and Steinernema feltiae in biological control of insect pests, they are produced in liquid culture on artificial media pre-incubated with their symbiotic bacteria Xenorhabdus nematophila and Xenorhabdus bovienii, respectively. After 1 day of the bacterial culture, nematode dauer juveniles (DJs) are inoculated, which recover development. The adult nematodes produce DJ offspring, which are harvested and can be sprayed. This study determined optimal temperatures to obtain high DJ progeny within a short process time. Temperatures assessed were 23 degrees C, 25 degrees C, 27 degrees C, and 29 degrees C for S. carpocapsae and 20 degrees C, 23 degrees C, 25 degrees C, and 27 degrees C for S. feltiae. The recovery of inoculated DJs was hardly affected and was reduced only in S. carpocapsae at 29 degrees C. The fecundity (eggs in uterus) in S. carpocapsae reached a maximum at 27 degrees C; whereas, ...

2009-05-20

37

Prevalence of gallstone disease in an Italian adult female population. Rome Group for the Epidemiology and Prevention of Cholelithiasis (GREPCO).  

Science.gov (United States)

A population of female civil servants in Rome, Italy, was investigated to determine the prevalence of symptomatic and asymptomatic gallstone disease and to define the associated factors. Field activities started in February 1981 and concluded in April 1982. Diagnosis was assessed by real time ultrasonography. Prevalence of gallstone disease increased with age from 2.5% in the 20- to 29-year-old age group to 25.0% in the 60- to 64-year-old age group, based on both presence of gallstones and history of cholecystectomy. Only one third of the women with gallstones had complained of at least one episode of biliary pain in the last five years. Frequency of "minor" dyspeptic symptoms was not different between women with and those without gallstones. In a multiple logistic function analysis, a positive association was found between age, body mass index, parity, and prevalence of gallstone disease. No association was demonstrated between the presence of gallstones or cholecystectomy and other ...

1984-05-01

38

Molecular evidence for variation in polyandry among praying mantids (Mantodea: Ciulfina)  

British Library Electronic Table of Contents (United Kingdom)

Abstract Estimating paternity patterns provides insights into the importance of competing evolutionary forces on mating systems. The number of sires contributing to a female's offspring is mostly influenced by her relative promiscuity. However, in a postcopulatory context, it will also be affected by sperm competition and cryptic female choice. Here, we describe the paternity patterns of two species of praying mantis from the genus Ciulfina, the agile praying mantid. This study is the first to describe patterns of paternity in the Mantodea. We found a variation in paternity in these two closely related species. Ciulfina rentzi exhibited single paternity, with a single male siring all offspring within a clutch. By contrast, Ciulfina klassi displayed multiple paternity, with the minimum numb...

2011-01-01

39

A Lamarckian Hybrid of Differential Evolution and Conjugate Gradients for Neural Network Training  

British Library Electronic Table of Contents (United Kingdom)

The paper describes two schemes that follow the model of Lamarckian evolution and combine differential evolution (DE), which is a population-based stochastic global search method, with the local optimization algorithm of conjugate gradients (CG). In the first, each offspring is fine-tuned by CG before competing with their parents. In the other CG is used to improve both parents and offspring in a manner that is completely seamless for individuals that survive more than one generation. Experiments involved training weights of feed-forward neural networks to solve three synthetic and four real-life problems. In six out of seven cases the DE?CG hybrid, which preserves and uses information on each solution?s local optimization process, outperformed two recent variants of DE.

2010-01-01

40

Hemoglobin of mice with radiation-induced mutations at the hemoglobin loci  

International Nuclear Information System (INIS)

Chemical analyses were done on the abnormal hemoglobins of the five (101 x SEC)F_1 offspring of X- irradiated adult SEC mice to determine which hemoglobin genes were expressed in each hemoglobin variant. Three offspring of irradiated SEC males did not express either of the two kinds of #alpha#-chains normally found in all SEC mice. The deficient #alpha#-chain synthesis caused these mice to exhibit an #alpha#-thalassemia similar to human #alpha#-thalassemia. Scanning electron microscopy was used to show that many erythrocytes of mice with #alpha#-thalassemia have bizarre shapes; e.g. many erythrocytes appeared flattened or had thorny projections (acanthocytes). One mutant with a tandem duplication of a segment of chromosome 7 (site of locus determining #beta#-chain structure) produced twice as much SEC as 101 #beta#-chain polypeptides. One mutant that probably arose by non-disjunction of chromosome 7's in its unirradiated 101 mother and loss of ...

41

Distribution of lead in lactating mice and suckling offspring with special emphasis on the mammary gland  

Energy Technology Data Exchange (ETDEWEB)

The distribution of lead in lactating mice and suckling offspring was studied with whole body autoradiography at 4 and 24 h after a single intravenous injection of {sup 203}Pb (50 mmol Pb/kg) to the dams. In the lactating mice on day 14 of lactation, the highest uptake of radioactivity at 4 h after administration was recorded in renal cortex, skeleton and liver. A high uptake was also evident in the mannary gland. At 24 h after administration, the radioactivity had decreased in most organs except in the skeleton. In the suckling pups, exposed to lead only via dams` milk for 24 h, the highest level of radioactivity was present in the intestinal mucosa and a much lower level of radioactivity was present in the skeleton. The mammary glands from mice given three daily intravenous injections of 240 {mu}mol Pb/kg were examined with X-ray microanalysis. At 4 h after the last injection, lead was found associated with casein micelles both inside the alveolar cell and in the ...

1996-01-01

42

Distribution of lead in lactating mice and suckling offspring with special emphasis on the mammary gland  

International Nuclear Information System (INIS)

The distribution of lead in lactating mice and suckling offspring was studied with whole body autoradiography at 4 and 24 h after a single intravenous injection of "2"0"3Pb (50 mmol Pb/kg) to the dams. In the lactating mice on day 14 of lactation, the highest uptake of radioactivity at 4 h after administration was recorded in renal cortex, skeleton and liver. A high uptake was also evident in the mannary gland. At 24 h after administration, the radioactivity had decreased in most organs except in the skeleton. In the suckling pups, exposed to lead only via dams' milk for 24 h, the highest level of radioactivity was present in the intestinal mucosa and a much lower level of radioactivity was present in the skeleton. The mammary glands from mice given three daily intravenous injections of 240 #mu#mol Pb/kg were examined with X-ray microanalysis. At 4 h after the last injection, lead was found associated with casein micelles both inside the alveolar cell and in the ...

43

Cerebral biochemical abnormalities in experimental maternal phenylketonuria: gangliosides and sialoglycoproteins  

International Nuclear Information System (INIS)

The present study sought a biochemical explanation for retarded brain development in the heterozygous offspring of the phenylketonuric (PKU) mother. Two rat models of simulated maternal PKU, one induced by p-chloropheylalanine and phenylalanine and the other by phenylacetate, were employed in this investigation. Maternal PKU had no influence on cerebral concentrations of DNA, protein, and cholesterol, which were normal in the 2 d old pup. However, there was a noticeable disruption of the normal ganglioside pattern and a significant reduction of sialoglycoproteins. Concomitant with a delayed drop in the gangliosides Q/sub 1b/ and D_3, was a slower rise in M_1 and D/sub 1a/. At least 66% of sialoglycoproteins located on SDS-PAGE gel chromatograms, by radioactivity incorporated in vivo from radiolabeled N-acetylmannosamine and by ("3H) sialic acid released by neuraminidase from periodate-("3H) borohydride labeled glycoproteins, have mobilites of the cell adhesion ...

44

Dose dependent transfer of [sup 203]lead to milk and tissue uptake in suckling offspring studied in rats and mice  

Energy Technology Data Exchange (ETDEWEB)

The dose-dependent transfer of [sup 203]Pb to milk and uptake in suckling rats and mice during a three-day nursing period was studied. On day 14 of lactation, the dams were administered a single intravenous dose of lead, labelled with [sup 203]Pb, in four or five doses from 0.0005 to 2.0 mg Pb/kg b.wt. There was a linear relationship between Pb levels in plasma and milk of both species. The Pb milk: plasma ratios at 24 hr after administration were 119 and 89 in mice and rats, respectively. At 72 hr the Pb milk: plasma ratio had decreased to 72 in mice and 35 in rats. The tissue levels of lead in the suckling rats and mice were also linearly correlated with lead concentration in milk at 72 hr, showing that milk could be used as an indicator of lead exposure to the suckling offspring. It is concluded that lead is transported into rat and mouse milk to a very high extent and the excretion into milk is more efficient in mice than in rats. On the other hand, rat pups ...

1993-09-01

45

The genetics and evolution of obligate reproductive parasitism in Trichogramma pretiosum infected with parthenogenesis-inducing Wolbachia  

British Library Electronic Table of Contents (United Kingdom)

Parthenogenesis-inducing (PI) Wolbachia belong to a class of intracellular symbionts that distort the offspring sex ratio of their hosts toward a female bias. In many PI Wolbachia-infected species sex ratio distortion has reached its ultimate expression-fixation of infection and all-female populations. This is only possible with thelytokous PI symbionts as they provide an alternative form of reproduction and remove the requirement for males and sexual reproduction. Many populations fixed for PI Wolbachia infection have lost the ability to reproduce sexually, even when cured of the infection. We examine one such population in the species Trichogramma pretiosum. Through a series of backcrossing experiments with an uninfected Trichogramma pretiosum population we were able to show that the gen...

2011-01-01

46

The epidemiology of Graves' disease: Evidence of a genetic and an environmental contribution  

British Library Electronic Table of Contents (United Kingdom)

Previous family and twin studies have indicated that Graves' disease has a heritable component. Family studies have also shown that some autoimmune disease cluster in families and genetic studies have been able to show shared susceptibility genes. In the present nation-wide study we describe familial risk for Graves' disease among parents and offspring, singleton siblings, twins and spouses with regard to age of onset, gender and number and type of affected family members. Additionally familial association of Graves' disease with any of 33 other autoimmune and related conditions was analyzed. The Swedish Multigeneration Register on 0-75-year-old subjects was linked to the Hospital Discharge Register from years 1987-2007. Standardized incidence ratios (SIRs) were calculated for individuals ...

2010-01-01

47

Parental Subfecundity and Risk of Decreased Semen Quality in the Male Offspring: A Follow-up Study  

British Library Electronic Table of Contents (United Kingdom)

A few studies have found poor semen quality in sons whose mothers have received fertility treatment, but it is unknown whether the poor semen quality is related to the infertility treatment or to infertility per se, for example, whether it is caused by hereditable factors. Using data from a population-based, Danish follow-up study conducted in 2005-2006, the authors of the present study examined whether sons of subfertile couples who had not received fertility treatment had poorer semen quality than sons of fertile couples. Among the 311 participants, an inverse association between parental waiting time to pregnancy and both semen volume and total sperm count was observed (p trend = 0.04 and p trend = 0.046, respectively). Semen volume in sons of subfertile parents (pregnant after ?1 ye...

2008-01-01

48

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters  

British Library Electronic Table of Contents (United Kingdom)

Research on hematological disorders relies on suitable animal models. We retrospectively evaluated the use of the hematological parameters hematocrit (HCT), hemoglobin (HGB), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), red blood cell count (RBC), white blood cell count (WBC), and platelet count (PLT) in the phenotype-driven Munich N-ethyl-N-nitrosourea (ENU) mouse mutagenesis project as parameters for the generation of novel animal models for human diseases. The analysis was carried out on more than 16,000 G1 and G3 offspring of chemically mutagenized inbred C3H mice to detect dominant and recessive mutations leading to deviations in the levels of the chosen parameters. Identification of animals exhibiting altered valu...

2011-01-01

49

Radiation-induced mutations at mouse hemoglobin loci  

International Nuclear Information System (INIS)

In experiments designed to detect new mutations affecting hemoglobin, we irradiated the male or female parent in reciprocal crosses of two mouse strains that differ in alleles at the hemoglobin (Hba, Hbb) loci as well as at five other specific loci. Offspring were analyzed for hemoglobin properties (electrophoretic pattern, solubility, crystal pattern), serum albumin differences, erythrocyte lysis, reticulocyte count, and external appearance. Five hemoglobin variants were found among the mutants. In three, the genetic contribution from the irradiated father was not expressed with regard to the #alpha#-chain; one carried a tandem duplication (the first known case in the mouse) involving Hbb; and one probably resulted from double nondisjunction of chromosome 7. The finding that major chromosome aberratios can mimic hemoglobin mutations indicates the need, in similar experiments, to follow F_1 screening with thorough cytogenetic analysis. The variants in which there ...

50

Operant behavior of rats exposed to lead before or after weaning  

Energy Technology Data Exchange (ETDEWEB)

Rats were exposed to lead (Pb) before or after weaning. For preweaning exposures, nursing dams received 0.2% Pb acetate(1090 ppm Pb) in drinking water. Offspring treated after weaning consumed the same concentration. Tapwater served as the control fluid. Pre-post treatments were distributed among four experimental groups of 10 rats each: tap water-tap water, Pb-tap water, tap water-Pb, Pb-Pb. Operant behavior training began on Postnatal Day 58. Animals performed on a multiple reinforcement schedule of food presentation consisting of fixed-interval, fixed-ratio, and time out components.Statistical analyses of experimental sessions 4 to 11 (Postnatal Days 72 to 79) revealed that postweaning exposure significantly lengthened the median interval (interresponse time) between consecutive responses on both the interval and ratio schedules. Preweaning exposure alone tended to produce a shortening of the median interresponse time. Other performance indices and subsequence ...

1982-01-01

51

Male mammals respond to a risk of sperm competition conveyed by odours of conspecific males  

Science.gov (United States)

Sperm competition occurs when a female copulates with two or more males and the sperm of those males compete within the female's reproductive tract to fertilize her eggs. The frequent occurrence of sperm competition has forced males of many species to develop different strategies to overcome the sperm of competing males. A prevalent strategy is for males to increase their sperm investment (total number of sperm allocated by a male to a particular female) after detecting a risk of sperm competition. It has been shown that the proportion of sperm that one male contributes to the sperm pool of a female is correlated with the proportion of offspring sired by that male. Therefore, by increasing his sperm investment a male may bias a potential sperm competition in his favour. Here we show that male meadow voles, Microtus pennsylvanicus, increase their sperm investment when they mate in the presence of another male's odours. Such an increase in sperm investment does not ...

2004-09-01

52

Lead and calcium distributions in blood, plasma, and milk of the lactating mouse  

Energy Technology Data Exchange (ETDEWEB)

Although it has been established that lead is transferred in milk from mother to suckling offspring, the physiological processes and parameters involved are not well understood. Single i.v. doses (0.2 mg/kg) or p.o. doses (2 mg/kg) of radiolabeled lead were administered to lactating and nonlactating female mice, and lead concentrations in blood, plasma, and milk were determined during a 21-day period. Large differences in lead elimination were observed between lactating and nonlactation mice. A significant fraction (25%) of the initial maternal dose (absorbed dose) was transferred to the suckling pups. The ratio of lead concentration in milk to lead concentration in plasma was found to be nearly constant over time. However, the milk-to-blood concentration ratios decreased during the same period. Furthermore, the concentration of lead in milk exceeded the plasma concentration by a factor of approximately 25, indicating that there is a physiological process(es) which ...

1980-01-01

53

Is nest-drifting behaviour an insurance policy for maximising indirect fitness in primitively eusocial paper wasps?  

Environmental Research Database

ObjectivesThe main objectives of this project are: 1. To determine whether nest-drifting behaviour allows helpers to maximise their indirect fitness in the paper wasp Polistes canadensis. Specifically, I will test a) whether nest-drifters apportion helping effort in relation to the productivity benefits of different nests (hypothesis 1a), and b) whether nest-drifters can adjust their investment in response to changes in the productivity payoffs of different nests (hypothesis 1b). 2. To determine [continued...]DescriptionDarwin's theory of natural selection predicts that organisms should act selfishly in order to pass on as many of their genes to the next generation as possible. The evolution of social behaviour is a paradox because it requires that some individuals forgo reproduction in order to help raise the offspring of others. Explaining the evolution of helping behaviour in animal societies has been a major focus for evolutionary biologists ever since Darwin. ...

2011-01-20

54

Association tests in nuclear families.  

Science.gov (United States)

We present a conditional likelihood approach for testing linkage disequilibrium in nuclear families having multiple affected offspring. The likelihood, conditioned on the identity-by-descent (IBD) structure of the sibling genotypes, is unaffected by familial correlation in disease status that arises from linkage between a marker locus and the unobserved trait locus. Two such conditional likelihoods are compared: one that conditions on IBD and phase of the transmitted alleles and a second which conditions only on IBD of the transmitted alleles. Under the log-additive model, the first likelihood is equivalent to the allele-counting methods proposed in the literature. The second likelihood is valid under the added assumption of equal male and female recombination fractions. In a simulation study, we demonstrated that in sibships having two or three affected siblings the score test from each likelihood had the correct test size for testing disequilibrium. They also led ...

2001-01-01

55

Survey and analysis of simple sequence repeats in the Laccaria bicolor genome, with development of microsatellite markers  

Energy Technology Data Exchange (ETDEWEB)

It is becoming clear that simple sequence repeats (SSRs) play a significant role in fungal genome organization, and they are a large source of genetic markers for population genetics and meiotic maps. We identified SSRs in the Laccaria bicolor genome by in silico survey and analyzed their distribution in the different genomic regions. We also compared the abundance and distribution of SSRs in L. bicolor with those of the following fungal genomes: Phanerochaete chrysosporium, Coprinopsis cinerea, Ustilago maydis, Cryptococcus neoformans, Aspergillus nidulans, Magnaporthe grisea, Neurospora crassa and Saccharomyces cerevisiae. Using the MISA computer program, we detected 277,062 SSRs in the L. bicolor genome representing 8% of the assembled genomic sequence. Among the analyzed basidiomycetes, L. bicolor exhibited the highest SSR density although no correlation between relative abundance and the genome sizes was observed. In most genomes the short motifs (mono- to trinucleotides) were ...

2011-01-01

56

Linkage analysis in familial Angelman syndrome  

Energy Technology Data Exchange (ETDEWEB)

Familial Angelman syndrome (AS) can result from mutations in chromosome 15q11q13 that, when transmitted from father to child, result in no phenotypic abnormality but, when transmitted from mother to child, cause AS. These mutations therefore behave neither as dominant nor as recessive mutations but, rather, show an imprinted mode of inheritance. The authors have analyzed two sibling pairs with AS and a larger family with four AS offspring of three sisters with several recently described microsatellite polymorphisms in the AS region. AS siblings inherited the same maternal alleles at the GABRB3 and GABRA5 loci, and the unaffected siblings of AS individuals inherited the other maternal alleles at these loci. In one of the AS sibling pairs, analysis of a recombination event indicates that the mutation responsible for AS is distal to locus D15S63. This result is consistent with a previously described imprinted submicroscopic deletion causing AS, a deletion that ...

1993-07-01

57

Impaired neonatal survival of pro-opiomelanocortin null mutants.  

Science.gov (United States)

Intercrosses of heterozygous pro-opiomelanocortin (POMC) mice result in homozygous null progeny at lower frequencies than expected. Genotyping offspring at pre-, peri-, and postnatal stages revealed that over half of homozygous null mutants die in the early postnatal stages. To investigate the reasons for this early postnatal lethality, we analyzed in detail different parameters in the initial hours after birth. POMC null mutants born to heterozygous dams presented at birth with corticosterone levels no different from wildtype littermates, were euglycemic, and had normal liver glycogen stores. However, already 30 min after birth corticosterone levels dropped by 80% and were undetectable thereafter, while corticosterone levels in wildtype animals increased during postnatal hours. Circulating adrenaline was almost below detection 1h after birth. Blood glucose levels fell sharply in all genotypes within 30 min after birth; however, wildtype and heterozygous pups ...

2010-12-22

58

Assessment of chromosomal abnormalities in sperm of infertile men using sperm karyotyping and multicolour fluorescence in situ hybridization (FISH)  

Energy Technology Data Exchange (ETDEWEB)

Individuals with male factor infertility resulting from idiopathic oligo-, astheno- or teratozoospermia are frequently offered IVF in an attempt to increase their chances of having a child. A concern remains whether these infertile males have an elevated risk of transmitting chromosomal abnormalities to their offspring. Sperm chromosomal complements from these men were assayed using the human sperm/hamster oocyte fusion system and fluorescence in situ hybridization (FISH) on sperm nuclei. For each of 5 infertile patients, 100 sperm karyotypes were analyzed and multicolour FISH analysis was performed on a minimum of 10,000 sperm nuclei for each chromosome-specific DNA probe for chromosomes 1 (pUC1.77), 12 (D12Z3), X (XC) and Y (DYZ3). As a group, the infertile patients showed increased frequencies of both numerical ({chi}{sup 2}=17.26, {proportional_to} <0.001) and total abnormalities ({chi}{sup 2}=7.78, {proportional_to} <0.01) relative to control donors when ...

1994-09-01

59

Influence of a combination of two tetrachlorobiphenyl congeners (PCB 47; PCB 77) on thyroid status, choline acetyltransferase (ChAT) activity, and short- and long-term memory in 30-day-old Sprague-Dawley rats  

International Nuclear Information System (INIS)

The important role of thyroid hormones in growth and development, maintenance of body temperature, digestion, cardiac function, and normal brain development can be disrupted by environmental contaminants like polychlorinated biphenyls (PCB). Polychlorinated biphenyls are environmental contaminants that are widespread, persistent, lipophilic, and bioaccumulate through food webs, concentrating in adipose tissue. Placental and lactational PCB exposure of offspring causes metabolic and endocrine disruptions including hypothyroxinemia, spatial learning and memory deficits, neurochemical and neurobehavioral alterations, and reproductive problems. Previous studies in our lab using the individual congeners PCB 47 (2,2',4,4'-tetrachlorobiphenyl, ortho-substituted) and PCB 77 (3,3',4,4'-tetrachlorobiphenyl, non-ortho-substituted) have demonstrated alterations in thyroid hormone levels, alterations in brain choline acetyltransferase (ChAT) activity, and spatial learning ...

2004-10-15

60

Cytopathic Effects of Viruses Protocols  

Science.gov (United States)

Protocols for using Cytopathic Effects of Viruses

2007-09-29

61

Effect of Pressures up to 2.0 GPa on the Mechanical ...  

Science.gov (United States)

... hydrostatic pressures up to 700 MPa. The effect of pressure on the ultimate compressive strength is shown. The effect of size on ...

66

Effects and side-effects of integrating care: the case of mental health care in the Netherlands  

UK PubMed Central (United Kingdom)

PurposeDescription and analysis of the effects and side-effects of integrated mental health care in the Netherlands.Context of caseDue...Full Text Available

67

Solar wind effect on the muon flux at sea level  

CERN Document Server

Solar wind effect on the muon flux at sea level

2005-01-01

68

New Effective Pesticides  

International Science & Technology Center (ISTC)

Development the New Effective Pesticides in the Series of Pyrimine and Sym-Triazine Derivatives

69

The Effect of Morpholine/Boric Acid/Hydrazine Chemistry on ...  

Science.gov (United States)

... the effect of MBH on steam generator crevice corrosion; model boiler test results show that MBH is effective against denting corrosion and Alloy 600 ...

70

Electromagnetic Effects Requirements for Systems.  

Science.gov (United States)

This standard establishes requirements, verification criteria, and contractor tasks for electromagnetic effects protection of airborne, ground, and support systems. These effects include electromagnetic compatibility, electromagnetic interference, lightni...

1993-01-01

71

A novel procedure for assessing the effects of drugs on satiation in baboons: effects of memantine and dexfenfluramine  

UK PubMed Central (United Kingdom)

RationaleProcedures for studying the effects of medications on satiation will assist the development of obesity medications.ObjectivesFull Text Available

2008-09-01

111

The effects of organosulfur compounds upon the storage stability of Jet A fuel  

Science.gov (United States)

This study examined the effect of sulfur-containing compounds on the storage stability of Jet A

1981-01-01

112

The Effects of Flame Retardant Combinations in PVC ...  

Science.gov (United States)

... Title : The Effects of Flame Retardant Combinations in PVC-Epoxidised Natural Rubber Miscible Blends: Antimony Trioxide in Combination with ...

1989-03-01

113

The Effect of the Temperature to Which the Material is Heated ...  

Science.gov (United States)

... The Effect of the Temperature to Which the Material is Heated on the Process of Formation of Intermetallic Compounds in Magnetic Pulse Welding,. ...

1980-09-01

114

Heavy Metals Effect on Animal Cells  

International Science & Technology Center (ISTC)

Studies of the Superheavy-metal Effect as a Stress-factor on Protein Biosynthesis and Cytoskeleton Integrity in Animal Cells

115

Effects of Pentobarbital Anesthesia on Survival, 'Escherichia ...  

Science.gov (United States)

... Title : Effects of Pentobarbital Anesthesia on Survival, 'Escherichia coli' Clearance, Glucose and Leukocyte Concentration in Dogs Subjected to ...

1978-08-28

116

Effect of dietary constituents on the absorption of lead in the human  

International Nuclear Information System (INIS)

... biological effects body burden diet intestinal absorption lead lead 203 man

1983-03-01

117

Effect of Yttrium on the Microstructure of Titanium Alloys,  

Science.gov (United States)

... Title : Effect of Yttrium on the Microstructure of Titanium Alloys,. ... The yttrium was added in the melting stage as an oxide or in the elemental form. ...

118

EFFECTS OF SHIELDING ON PROPERTIES OF EDDY ...  

Science.gov (United States)

... Accession Number : ADD323869. Title : EFFECTS OF SHIELDING ON PROPERTIES OF EDDY CURRENT PROBES WITH FERRITE CUP CORES. ...

1986-08-01

119

Diaphragm Rupture Effects on an Expanding Flow in a Tube.  

Science.gov (United States)

... The fundamental problem of diaphragm rupture was studied experimentally to determine the effects on an expanding flow in an evacuated tube. ...

1972-08-01

120

Coherency Effects on Retinal Neural Processes (ERG) of ...  

Science.gov (United States)

... Accession Number : ADA111683. Title : Coherency Effects on Retinal Neural Processes (ERG) of Pseudemys. Descriptive ...

1981-12-01

121

Learning Effect and Standardization Effect in NPP's Construction  

International Nuclear Information System (INIS)

This paper describes the learning effect and standardization effect in the nuclear power construction, analyses their influence degree on nuclear power economics. Furthermore, the paper provides the ideas on how to improve the economics of nuclear power through implementing the learning effect and standardization effect. The paper also concludes that the learning rate in China is better than the average value in the world by analysis actual example. (authors)

2009-09-01

122

Effective medium theory of the one-dimensional resonance phononic crystal  

International Nuclear Information System (INIS)

A general theoretical scheme to describe the effective modulus and mass density for acoustic metamaterials is presented. For such a purpose, an effective medium theory of a one-dimensional acoustic waveguide containing subwavelength-sized Helmholtz resonators is formulated. It is shown that, when the wavelength is much larger than the periodic length and the size of the resonators, the whole composite structure can be treated as an effective homogeneous medium in accounting for its acoustic properties. It is also shown that the acoustic characteristics, such as the effective modulus and the effective mass density, can be determined precisely from the transmission and the reflection data. The calculated effective modulus and effective mass density confirm that this structure behaves as a homogeneous metamaterial with a negative ...

2008-02-06

123

Physical mechanism in the free-electron laser  

International Nuclear Information System (INIS)

In this paper some physical mechanisms are described, which determine some new free-electron laser configurations. These mechanisms comprise some physical effects of the radiant emission of an electron beam at the interaction with the medium it is crossing. They are based on the Cherenkov effect, Smith-Purcell effect, optical klystron, Rumakhov effect and limited interaction effect. (Author).

1992-09-21

124

Ionising radiation. Part 2  

Energy Technology Data Exchange (ETDEWEB)

A brief tutorial on the health effects of ionising radiation is presented. The distinction between somatic and genetic health effects is explained. The two types of somatic health effects, i.e., acute and chronic effects, are discussed, as well as the concepts of ''deterministic'' and ''stochastic'' (also called ''probabilistic'') health effects. The possibility of cancer caused by DNA damage is discussed. The document ends with the definition of some key radiation terms.

2000-11-01

125

Effects of gamma irradiation on physiological effectiveness of Korean medicinal herbs  

Energy Technology Data Exchange (ETDEWEB)

Effects of gamma irradiation on the physiological effectiveness of Korean medicinal herbs were investigated. The physiological effectiveness including antioxidant and anticomplement function, nitrite scavenging and electron donating ability of Korean medicinal herbs by gamma irradiation at 10 kGy did not differ from that of the nonirradiated control.

1999-03-01

126

The effects of exercise and stress on the survival and maturation of adult-generated granule cells  

UK PubMed Central (United Kingdom)

Stress strongly inhibits proliferation of granule cell precursors in the dentate gyrus, while voluntary running has the opposite effect. Few studies, however, have examined the possible effects...Full Text Available

2009-10-01

127

TJ-41 Induces Apoptosis and Potentiates the Apoptotic Effects of 5-FU in Breast Cancer Cell Lines  

UK PubMed Central (United Kingdom)

Recent studies suggest that TJ-41, a herbal drug, possesses chemotherapeutic effects. Accordingly, this study was undertaken to investigate the anticarcinogenic effects of TJ-41 on human breast cancer...Full Text Available

2009-01-01

128

Mouse model predicts effects of smoking and varenicline on event-related potentials in humans  

UK PubMed Central (United Kingdom)

Background:Nicotine alters auditory event-related potentials (ERPs) in rodents and humans and is an effective treatment for smoking cessation. Less is known about the effects of...Full Text Available

2010-06-01

129

Memory effect in air in the presence of vacuum breakdown mechanism  

Science.gov (United States)

Investigation of memory effects in air at 0.7 mbar pressure in the presence of vacuum electrical breakdown mechanism has been performed in this paper. The memory effect has been followed using the time delay method.

2008-07-01

130

Health effects of urea formaldehyde foam insulation: evidence of causation.  

UK PubMed Central (United Kingdom)

Studies of health effects of urea formaldehyde foam insulation (UFFI) were critically reviewed by means of accepted rules for evidence of causation. Three categories of health effects were examined:...Full Text Available

1986-04-01

131

Epidemiological survey of the effects of low level radiation dose: a comparative assessment  

Energy Technology Data Exchange (ETDEWEB)

This volume presents the collations tables of a six volume comparative epidemiological survey of the effects of low level radiation dose. Data are collated for the effects observed in the following irradiated groups:- Preconception irradiation, intra-uterine irradiation, childhood irradiation, adult irradiation. (UK).

1993-10-01

132

Effects of calcium supplementation on bone density in healthy children: meta-analysis of randomised controlled trials  

UK PubMed Central (United Kingdom)

Objectives To assess the effectiveness of calcium supplementation for improving bone mineral density in healthy children and to determine if any effect is modified by other factors and...Full Text Available

2006-10-14

133

Cost-Effectiveness of an Opportunistic Screening Programme and Brief Intervention for Excessive Alcohol Use in Primary Care  

UK PubMed Central (United Kingdom)

BackgroundEffective prevention of excessive alcohol use has the potential to reduce the public burden of disease considerably. We investigated the cost-effectiveness of Screening...Full Text Available

134

Cost-Effectiveness Analysis of Proposed Effluent Limitations Guidelines and Standards for the Metal Products and Machinery Industry (Phase 1).  

Science.gov (United States)

This cost-effectiveness analysis supports the proposed effluent limitations guidelines and standards for the Metal Products and Machinery Industry (MP and M) Phase I Industry. The report assesses the cost-effectiveness of five regulatory options for indir...

1995-01-01

135

Beneficial Effect of a Short-Acting NO Donor for the Prevention of Neointimal Hyperplasia  

UK PubMed Central (United Kingdom)

Nitric oxide (NO)-based therapies effectively inhibit neointimal hyperplasia in animal models of arterial injury and bypass grafting, but are not available clinically. We created a simple, effective,...Full Text Available

2008-01-01

136

Assessing the effectiveness and cost effectiveness of adaptive e-Learning to improve dietary behaviour: protocol for a systematic review  

UK PubMed Central (United Kingdom)

BackgroundThe composition of habitual diets is associated with adverse or protective effects on aspects of health. Consequently, UK public health policy strongly advocates dietary...Full Text Available

137

Adding effect sizes to a systematic review on interventions for promoting physical activity among European teenagers  

UK PubMed Central (United Kingdom)

This commentary adds effect sizes to the recently published systematic review by De Meester and colleagues and provides a more detailed insight into the effectiveness of interventions to promote physical...Full Text Available

138

New concepts in risk assessment for patients with radiological treatment  

International Nuclear Information System (INIS)

In radiation risk assessment it must be differentiated between somatic and genetic effect on the one hand as well as between stochastic and non-stochastic effect on the other. According to definitions of the ICRP report 26 the limit for the dose equivalent of all tissues prevents non-stochastic radiation effects. With stochastic radiation effects probably exist no threshold doses; therefore the ALARA principle must be applied concerning radiation protection. The individual risk by stochastic radiation effects in its linear, linear-quadratic and quadratic extrapolations, respectively, is discussed in detail. The effective stochastic dose equivalent (H/sub eff/) as well as collective dose and collective damage are outlined.

1986-01-01

139

CT colonography and cost-effectiveness  

Energy Technology Data Exchange (ETDEWEB)

CT colonography (CTC) is increasingly advocated as an effective initial screening tool for colorectal cancer. Nowadays, policy-makers are increasingly interested in cost-effectiveness issues. A number of studies assessing the cost-effectiveness of CTC have been published to date. The majority of findings indicate that CTC is probably not cost-effective when colonoscopy is available, but this conclusion is sensitive to a number of key parameters. This review discusses the findings of these studies, and considers those factors which most influence final conclusions, notably intervention costs, compliance rates, effectiveness of colonoscopy, and the assumed prevalence and natural history of diminutive advanced polyps. (orig.)

2008-11-15

140

VIGILANCE, PREDATION RISK, AND THE ALLEE EFFECT IN DESERT BIGHORN SHEEP  

Science.gov (United States)

... 2004)068[0519:VPRATA]2.0.CO;2 VIGILANCE, PREDATION RISK, AND THE ALLEE EFFECT IN DESERT ... revealed that predation risk (as es...

141

Toxicological properties of lead.  

UK PubMed Central (United Kingdom)

The pathological effects of lead on the renal, nervous, reproductive, endocrine, and immune systems have been reviewed. Emphasis is placed on reported subclinical effects due to chronic, low-level lead...Full Text Available

1977-08-01

142

Technology Improvement Pathways to Cost-Effective Vehicle Electrification: Preprint  

Energy Technology Data Exchange (ETDEWEB)

This paper evaluates several approaches aimed at making plug-in electric vehicles (EV) and plug-in hybrid electric vehicles (PHEVs) cost-effective.

2010-02-01

143

THE BALDWIN EFFECT AND GENETIC ASSIMILATION: REVISITING TWO MECHANISMS OF EVOLUTIONARY CHANGE MEDIATED BY PHENOTYPIC ...  

Science.gov (United States)

... 1111/j.1558-5646.2007.00203.x THE BALDWIN EFFECT AND GENETIC ASSIMILATION: REVISITING TWO MECHANISMS OF ... to phenotypic plast...

144

Strong-interaction effect measurements in sigma hyperonic atoms of W and Pb  

Energy Technology Data Exchange (ETDEWEB)

Strong-interaction effects have been observed in the x-ray spectra of atoms formed with [Sigma][sup [minus

1993-03-01

145

Size Effects in Impact Damage of Composite Sandwich Panels Alan ...  

Science.gov (United States)

Wade. Jackson. - Army. VTD at NASA. Langley. ABSTRACT. Panel size has a large effect on the impact response and resultant damage level of honeycomb sandwich ...

146

Saturation effects at LHC energies  

CERN Document Server

Within the framework of a modified Balitsky-Kovchegov equation, we calculated and provide estimates of non-linear saturation effects expected in the LHC range of energies.

2005-01-01

147

Possible health effects of working with VDUs.  

UK PubMed Central (United Kingdom)

A summary of the effects presented here is given in the table. The designation "factor present" implies that there is knowledge (from human or animal studies, or both) of a specific factor(s) present...Full Text Available

1989-04-01

148

Mechanism of viscosity effect on magnetic island rotation  

Energy Technology Data Exchange (ETDEWEB)

It is shown that plasma viscosity does not influence the magnetic island rotation directly. Nevertheless, it leads to nonstationarity of the plasma velocity. This nonstationarity is the reason of the viscosity effect on island rotation. (author)

2000-04-01

149

Influence of nebivolol on anticonvulsant effect of lamotrigine  

UK PubMed Central (United Kingdom)

Objective:The present study describes the effect of nebivolol (NBV) either alone or in combination with lamotrigine (LTG) using increasing current electroshock seizures...Full Text Available

2009-02-01

150

Human factors  

Energy Technology Data Exchange (ETDEWEB)

This is a presentation on Human Factors in reactor operations. It discusses issues that deal with power plant operations, training and design, operational effectiveness and safety, supporting people to achieve effective and error free performance.

2002-07-01

151

Flame Retardant Effects in PVC-Epoxidised Natural Rubber ...  

Science.gov (United States)

... Title : Flame Retardant Effects in PVC-Epoxidised Natural Rubber Miscible Blends: Halogen and Non-Halogen Based Additives,. Corporate Author : ...

1989-03-01

152

Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and ...  

Science.gov (United States)

... Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and Genomic InstabilityMary Helen Barcellos-Hoff1a ... ...

153

Efficacy and adverse effects of intravenous lignocaine therapy in fibromyalgia syndrome  

UK PubMed Central (United Kingdom)

BackgroundTo investigate the effects of intravenous lignocaine infusions (IV lignocaine) in fibromyalgia.MethodsProspective study...Full Text Available

154

Effects of phenoxybenzamine on bladder neck opening1  

UK PubMed Central (United Kingdom)

A study of the effects of the action of phenoxybenzamine on bladder neck opening during micturition is reported. Twenty patients with symptoms of prostatism but minimal prostatic enlargement were studied....Full Text Available

1980-05-01

155

Effects of Yttrium Microalloying on the Epitaxial Grain Growth ...  

Science.gov (United States)

... Accession Number : ADA137272. Title : Effects of Yttrium Microalloying on the Epitaxial Grain Growth in Ti-6Al-4V Weld Fusion Zones. ...

1983-10-01

156

Effect of ginger on gastric motility and symptoms of functional dyspepsia  

UK PubMed Central (United Kingdom)

AIM: To evaluate the effects of ginger on gastric motility and emptying, abdominal symptoms, and hormones that influence motility in dyspepsia.METHODS: Eleven patients with functional dyspepsia...Full Text Available

2011-01-07

158

Effect of Roller Profile on Cylindrical Roller Bearing ... - GLTRS - NASA  

Science.gov (United States)

J.V. Poplawski and Associates, Bethlehem, Pennsylvania. Effect of Roller Profile on Cylindrical. Roller Bearing Life Prediction. NASA/TM2000-210368 ...

159

Effect of Registration on Cyclical Kinematic Data  

UK PubMed Central (United Kingdom)

Given growing interest in Functional Data Analysis (FDA) as a useful method for analyzing human movement data, it is critical to understand the effects of standard FDA procedures, including...Full Text Available

2010-08-26

160

Effect of Deforestation on a Southwest Ghana Dung Beetle Assemblage (Coleoptera: Scarabaeidae) at the Periphery of ...  

Science.gov (United States)

... 1081:EODOAS]2.0.CO;2 Effect of Deforestation on a Southwest Ghana Dung Beetle Assemblage (Coleoptera: ... The survey provided a...

161

Diagnostics of Radionuclides Effects Results  

International Science & Technology Center (ISTC)

Development of New Methods and Means of Assessing of Consequences of Radionuclide and Heavy Metal Salt Effect, Criteria of Forecasting Physiological State and Productivity of the Farm Animals under Conditions of Ecological Pollution of Environment

162

Cooperative Effects on Transient Spectral Hole Burning  

Science.gov (United States)

... of Dist SpeA tI/ __LLL5' Page 5. 3 the coherent effects on the spontaneous radiation, we calculate the pump- field-induced ...

1992-06-01

163

Cooperative Charging Effects of Fibers From Electrospinning ...  

Science.gov (United States)

... In the Proceedings of INTC 2003, we studied charging effects on target coverage during electrospinning (16). ... of Fibers from Electrospinning of ...

2005-01-05

164

Contamination Effects of Satellite Material Outgassing ...  

Science.gov (United States)

... A detailed analysis of QCM errors is ... Surface Effects of Satellite Outgassing Products." AIAA Journal ... 9. Rauschenbach, H. S. Solar Cell Array Design ...

1990-12-01

165

Camouflage Patterns-Effects of Size and Color.  

Science.gov (United States)

... CAMOUFLAGE PATTERS- EFFECTS OFSIZE AND COL0R.-(U I'. * ... Camouflage, survei.Ilance, countersurveiliance, vi~sion, color ...

1979-07-01

166

Biological radiation effects  

International Nuclear Information System (INIS)

The stages of processes leading to radiation damage are studied, as well as, the direct and indirect mechanics of its production. The radiation effects on nucleic acid and protein macro moleculas are treated. The physical and chemical factors that modify radiosensibility are analysed, in particular the oxygen effects, the sensibilization by analogues of nitrogen bases, post-effects, chemical protection and inherent cell factors. Consideration is given to restoration processes by excision of injured fragments, the bloching of the excision restoration processes, the restoration of lesions caused by ionizing radiations and to the restoration by genetic recombination. Referring to somatic effects of radiation, the early ones and the acute syndrome of radiation are discussed. The difference of radiosensibility observed in mammalian cells and main observable alterations in tissues and organs are commented. ...

1976-01-01

167

Atmospheric Scintillation Effects on Electromagnetic Weapons  

Science.gov (United States)

... 4. TITLE AND SUBTITLE Atmospheric Scintillation Effects on Electromagnetic Weapons 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. ...

2008-12-01

168

An Intrinsic Baldwin Effect in the H Beta Broad Emission Line in the Spectrum of NGC 5548  

Science.gov (United States)

We investigate the possibility of an intrinsic Baldwin effect (i.e., nonlinear emission-line

2003-01-01

169

A framework for evolutionary systems biology  

UK PubMed Central (United Kingdom)

BackgroundMany difficult problems in evolutionary genomics are related to mutations that have weak effects on fitness, as the consequences of mutations with large effects are often...Full Text Available

176

The intrinsic nature of the Baldwin effect  

Science.gov (United States)

The relationship between the fluxes of the two strongest UV emission lines and flux in the continuum

1992-01-01

190

THE EFFECTS OF ONE MEGACYCLE ULTRASONIC ...  

Science.gov (United States)

... ULTRASONIC VIBRATION TO PORTLAND CEMENT-WATER PASTE REDUCES THE ULTIMATE COMPRESSIVE STRENGTH OF MORTARS ...

1959-09-09

191

THE EFFECT OF FIBRE MISALIGNMENT ON THE ...  

Science.gov (United States)

... and testing of unidirectional composites, there are serious doubts about the possibility of obtaining a true ultimate compressive strength for this kind ...

192

Symposium (International) (4th) on DETONATION Held at ...  

Science.gov (United States)

... 442 RHF Stresau CONFINEMENT EFFECTS IN EXPLODING BRIDGEWIRE INITIATION OF DETONATION ..... ...

1965-10-15

194

Statistical cut-off criterion  

International Nuclear Information System (INIS)

... radiation effects human populations low dose irradiation neoplasms radiation

1980-01-01

195

Some comments on BEIR III  

International Nuclear Information System (INIS)

... organizations irradiation radiation doses radiation effects RADIATIONS.

1982-01-01

199

Radioprotective effect of fish products  

International Nuclear Information System (INIS)

New fish cans were prepared in the Institute of Fish Industry, Burgas (BG), containing pectin and additives. A biological experimental study was conducted to investigate the decontaminating effect of the new products. The results demonstrated no decontaminating effect in relation to radiocesium and radiostrontium. A pronounced prophylactic effect was observed in case of external irradiation, judged by endogenous spleen colonies. (author).

1993-12-02

200

Radiological equipment for emergencies  

Energy Technology Data Exchange (ETDEWEB)

A brief guide to training and equipment needed to effectively manage victims of radiation accidents. (DT)

1985-01-01

202

Radiation technology of wood-plastic composite materials  

International Nuclear Information System (INIS)

... radiation effects RADIATIONS. WOOD-PLASTIC COMPOSITES.

1981-10-02

203

Radiation effects on the shoot tip culture of chrysanthemum  

International Nuclear Information System (INIS)

Japanese (Mar 1974). Japan Mabuchi, Toshio Kuwada, Hikaru . Kagawa Univ.,

213

PRODUCT NAME BARITE  

Wastenet

the low levels of crystalline silica in this product, chronic health effects are not anticipated with normal

214

POTENTIATION BY PENTOBARBITAL OF THE PROTECTIVE ...  

Science.gov (United States)

... Accession Number : AD0268549. Title : POTENTIATION BY PENTOBARBITAL OF THE PROTECTIVE EFFECT OF AET AGAINST GAMMA RAYS. ...

1961-10-01

217

New physics effects on Higgs production at #gamma##gamma# colliders  

International Nuclear Information System (INIS)

We study heavy physics effects on the Higgs production in #gamma##gamma# fusion using the effective Lagrangian approach. We find that the effects coming from new physics may enhance the standard model predictions for the number of events expected in the final states b-barb, WW, and ZZ up to one order of magnitude, whereas the corresponding number of events for the final state t-bart may be enhanced up to two orders of magnitude.

1996-02-20

224

Implantation-plasma treatment of martensitic steel and titanium alloy  

Energy Technology Data Exchange (ETDEWEB)

One of the effective methods of deep modification of the surface of steels and alloys is the combination of ion implantation and plasma nitriding. In this work, the long-range effect is demonstrated in the case of combination of the effect of high- and low-energy ions of nitrogen on a martensitic steel for each ion implantation is usually not effective, and a titanium alloy used widely in industry.

2001-07-01

228

Ferromagnetism in Mn-doped GaAs layers: Effects of laser annealing  

Energy Technology Data Exchange (ETDEWEB)

The properties of Mn-doped GaAs layers grown by laser deposition were investigated with measurements of Hall effect and magneto-optical Kerr effect (MOKE). The electrical and magnetic parameters of the layers were defined by growth temperature and quantity of sputtered Mn. It was shown that room-temperature ferromagnetism is revealed by MOKE and, after ruby laser 25 ns pulse annealing, by Hall effect measurements.

2006-05-15

230

Environmental Effects on Oil Pipelines  

International Science & Technology Center (ISTC)

Determination of the Ecology Factor for the Magistral Oil Pipelines, Working in Difficult Hilly and Geology Conditions

267

Effective dose equivalent in nuclear medicine investigations  

International Nuclear Information System (INIS)

... radiation hazards hazards health hazards MEDICINE. SOMATICALLY

1984-05-07

285

Effect of KI on improving copper corrosion inhibition efficiency of benzotriazole in sulfuric acid electrolytes  

Energy Technology Data Exchange (ETDEWEB)

A synergistic effect exists when benzotriazole (BTAH) and iodide ions are used together to prevent the corrosion of copper in sulfuric acid. The nature of this effect has been studied systematically by using electrochemical techniques and X-ray photoelectron spectroscopy. The synergistic effect is due largely to the formation of a film of Cu(IBTA) complex and is probably polymeric in nature. This new complex film greatly depresses copper dissolution.

1993-10-01

287

Effect of High Omega-3 Fish Intake on Lipid Peroxidation  

Science.gov (United States)

Omega-3 Fatty Acids; Lipid Peroxidation

2011-05-31

309

EFFECT OF SHIP ATTITUDE AND SHIP MOTION ON PRIMARY COOLANT SYSTEM FLOW RATES. Appendix A: DERIVATION OF EFFECT OF ANGULAR ACCELERATION ON DRIVING HEAD IN A NATURAL CIRCULATION REACTOR  

Science.gov (United States)

Analytical techniques for analyzing the effects of ship motion and attitude on the primary coolant system flow rates are presented. Design data for minimizing these effects are given. (C.J.G.)

1960-01-24

310

EFFECT OF MICROSTRUCTURE ON THE STRENGTH ...  

Science.gov (United States)

... THE STRENGTH, TOUGHNESS, AND STRESS-CORROSION CRACKING SUSCEPTIBILITY OF A METASTABLE BETA TITANIUM ALLOY (Ti-11. ...

1970-02-01

311

Conversion gain in a Josephson effect mixer  

International Nuclear Information System (INIS)

United States Taur, Y. Claassen, JH Richards, PL Department of Physics,

312

Contribution to the radiation preparation of wood-plastic materials. Pt. 7  

International Nuclear Information System (INIS)

... odd nuclei organic compounds radiation effects radioisotopes synthesis

1974-01-01

313

Contribution to the radiation preparation of wood-plastic materials. Pt. 6  

International Nuclear Information System (INIS)

... compounds polymers polyolefins polyvinyls radiation effects SYNTHESIS.

1974-01-01

314

Contribution to the radiation preparation of wood-plastic materials Pt. 3  

International Nuclear Information System (INIS)

... compounds plants radiation effects radioisotopes reaction kinetics trees

1974-01-01

315

Continuous Strategy Development for Effects-Based ...  

Science.gov (United States)

... BAE Systems Advanced Information Technologies, Inc. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. ...

2006-02-01

316

Climate Change: The Role of Particles and Gases  

ScienceCinema

...global warming ...the effects of global warming ...also the ? that global warming ...

318

Calculation of some energetic parameters of astatine compounds  

International Nuclear Information System (INIS)

... astatine complexes astatine compounds coulomb energy effective charge

319

CRC handbook of biological effects of electromagnetic fields  

Energy Technology Data Exchange (ETDEWEB)

This book presents the current knowledge about the effects of electromagnetic fields on living matter. The three-part format covers dielectric permittivity and electrical conductivity of biological materials; effects of direct current and low frequency fields; and effects of radio frequency (including microwave) fields. The parts are designed to be consulted independently or in sequence, depending upon the needs of the reader. Useful appendixes on measurement units and safety standards are also included.

1986-01-01

320

Biophotonics and Bone Biology  

Science.gov (United States)

One of the more-serious side effects of extended space flight is an accelerated bone loss

2004-01-01

336

ADULT ACQUIRED TOLERANCE TO HOMOGRAFTS.  

Science.gov (United States)

... The effectiveness of immune suppression with both 6-mercaptopurine and methotrexate was insufficient to permit induction of a clinically useful ...

1967-07-31

337

A study of the Baldwin effect in the IUE data set  

Science.gov (United States)

The paper investigates the controversial relation between the continuum luminosity and the C IV 1550 emission-line strength in the spectra of quasars, commonly referred to as the Baldwin effect, as a possible indicator of absolute luminosity. It is concluded that the Baldwin effect does represent a physical correlation between the continuum and the C IV 1550 equivalent width rather than a consequence of selection effects. In addition to the C IV results, a similar relation is found for the Lyman-alpha emission line. 38 refs.

1990-07-01

343

The importance of axial effects for borehole design of geothermal heat-pump systems  

Energy Technology Data Exchange (ETDEWEB)

This paper studies the effects of axial heat conduction in boreholes used in geothermal heat pump systems. The axial effects are examined by comparing the results obtained using the finite and infinite line source methods. Using various practical design problems, it is shown that axial effects are relatively important. Unsurprisingly, short boreholes and unbalanced yearly ground loads lead to stronger axial effects. In one example considered, it is shown that the borehole length is 15% shorter when axial conduction effects are considered. In another example dealing with underground water freezing, the amount of energy that has to be removed to freeze the ground is three times higher when axial effects are considered. (author)

2010-04-15

344

Numerical analysis of methane-air combustion considering radiation effect  

Energy Technology Data Exchange (ETDEWEB)

Turbulent premixed methane-air combustion in a cylindrical chamber is numerically simulated considering radiation effect. Reaction rates are considered as minimum rates between Arrhenius rates and eddy break up rates. A five step reduced mechanism is used. Turbulent modeling is done via standard k-{epsilon} model imposed by empirical inlet boundary conditions. Source terms of energy equation consist of reaction rates and radiation effects. The discrete ordinate method (DOM) is employed to solve the radiative transfer equation (RTE) and the weighted sum of gray gas model (WSGGM) is imposed to consider radiation effect of non-gray gases. The results indicate that in the case of turbulent combusting flows, the effect of radiation of gases can affect the temperature and species concentrations. The numerical results obtained considering radiation effect are closer to the experimental ...

2008-12-15

345

Numerical analysis of methane-air combustion considering radiation effect  

International Nuclear Information System (INIS)

Turbulent premixed methane-air combustion in a cylindrical chamber is numerically simulated considering radiation effect. Reaction rates are considered as minimum rates between Arrhenius rates and eddy break up rates. A five step reduced mechanism is used. Turbulent modeling is done via standard k-? model imposed by empirical inlet boundary conditions. Source terms of energy equation consist of reaction rates and radiation effects. The discrete ordinate method (DOM) is employed to solve the radiative transfer equation (RTE) and the weighted sum of gray gas model (WSGGM) is imposed to consider radiation effect of non-gray gases. The results indicate that in the case of turbulent combusting flows, the effect of radiation of gases can affect the temperature and species concentrations. The numerical results obtained considering radiation effect are closer to the experimental data than ...

2008-12-01

346

Biological effects of electromagnetic radiation in the microwave range  

Energy Technology Data Exchange (ETDEWEB)

The book examines current experimental and clinical knowledge concerning the biological and biophysical effects of electromagnetic radiation, particularly that in the microwave range. The biophysical bases of the interaction of electromagnetic radiation with matter are reviewed with emphasis on biological systems, and the effects of radiation on critical biological systems, including the nervous, reproductive, visual and blood-forming systems are compared. Data concerning the lethal effects of nonionizing radiation is presented and characteristics of the effects of electromagnetic radiation on the whole mammalian organisms are examined. Various reactions of the neuroendocrine system to electromagnetic radiation are described, with particular attention given to the adrenal system, and the combined effects of ionizing and microwave radiation in the flight environment are discussed. ...

1980-01-01

347

Afferent mechanisms of microwave-induced biological effects. Annual report, 1 June 1985-31 May 1986  

Energy Technology Data Exchange (ETDEWEB)

Effects of 2450-MHz circularly polarized microwave irradiation on central nervous system functions were studied. Pulsed (microsecond, 500 pps) microwaves decreased high-affinity sodium-dependent choline uptake in the hippocampus and frontal cortex of the rat. The effect on hippocampal choline uptake was blocked by pretreatment with narcotic antagonists. Continuous-wave microwaves of the same power density decreased choline uptake in the frontal cortex only. Furthermore, it was found that the effects of pulsed microwaves on central cholinergic activity are classically conditionable to cues in the exposure environment. The hypothesis that some of the neurological effects of pulsed microwave irradiation are caused by its effect on the auditory system was investigated. Effects of pink noise and pulsed microwaves were compared.

1986-07-01

348

Effect of humidity in a mixture on combustion (Part 1). Effect on laminar burning velocity  

Energy Technology Data Exchange (ETDEWEB)

In order to investigate the effect of humidity on laminar burning velocity(S), the effect of humidity on the combustion reaction and radiation intensity was studied, taking account of dilution gases such as CO/sub 2/ and Ar which has the approximately identical characteristics to exhaust gas circulation(EGR) gas used to prevent NOx discharge from engines. According to the heat reaction theory, mean specific heat(C) of mixture, mean molecular weight(M) and adiabatic flame temperature(T) etc. were said to affect S but from experimental results, the effect of M and C could be ignored, compared with the effect of T. The relationship between S and H/sub 2/O, Ar of CO/sub 2/% in mixture of diluted gases was clarified. The effect of H/sub 2/O on S was mainly caused by changes of T. The effect of radical C/sub 2/, CH and OH on radiation intensity was similar to that of ...

1987-08-25

349

The benefits of low level radiation  

Energy Technology Data Exchange (ETDEWEB)

The assumed linear relationship between exposure to radiation and cancer incidence is questioned in this article. The current research data on radiation effects at the cellular level is reviewed, as are epidemiological studies of background radiation effects and health effects of populations exposed to low levels of radiation exposure via employment or medical treatments. Statistics reveal that threshold levels currently in force need to be reviewed. Some evidence of beneficial effects of low level radiation exposure effects of low level radiation exposure is also presented, and so regulations should be reviewed at an international level. (UK).

1997-06-01

350

Nucleon and meson effective masses in the relativistic mean-field theory  

Energy Technology Data Exchange (ETDEWEB)

Nucleon and meson effective masses in the nonlinear relativistic mean-field theory introducing a nonlinear {omega}-{rho} and {sigma} coupling motivated by the quark-meson coupling model is explored. It is shown that, in contrast to the usual Walecka model, not only the effective nucleon mass m{sub eff,N} but also the effective {sigma},{rho} meson masses (m{sub eff{sigma}},m{sub eff,{rho}}) and the effective {omega} meson mass m{sub eff,{omega}} are nucleon density dependent. (author)

2001-10-01

351

Nucleon and meson effective masses in the relativistic mean-field theory  

International Nuclear Information System (INIS)

Nucleon and meson effective masses in the nonlinear relativistic mean-field theory introducing a nonlinear #omega#-#rho# and #sigma# coupling motivated by the quark-meson coupling model is explored. It is shown that, in contrast to the usual Walecka model, not only the effective nucleon mass m_e_f_f_,_N but also the effective #sigma#,#rho# meson masses (m_e_f_f_#sigma#,m_e_f_f_,_#rho#) and the effective #omega# meson mass m_e_f_f_,_#omega# are nucleon density dependent. (author)

2001-10-01

352

Gravitational Waves and the Sagnac Effect  

CERN Document Server

We consider light waves propagating clockwise and other light waves propagating counterclockwise around a closed path in a plane (theoretically with the help of stationary mirrors). The time difference between the two light propagating path orientations constitutes the Sagnac effect. The general relativistic expression for the Sagnac effect is discussed. It is shown that a gravitational wave incident to the light beams at an arbitrary angle will not induce a Sagnac effect so long as the wave length of the weak gravitational wave is long on the length scale of the closed light beam paths. The gravitational wave induced Sagnac effect is thereby null.

2003-01-01

353

Effects of focused ion beam milling on the nanomechanical behavior of a molybdenum-alloy single crystal  

International Nuclear Information System (INIS)

Nanoindentation was performed on a Mo-alloy single crystal to investigate effects of focused ion beam (FIB) milling on mechanical behavior. On a non-FIB-milled surface, pop-ins were observed on all load-displacement curves corresponding to a transition from elastic to plastic deformation. Similar pop-ins were not detected on surfaces subjected to FIB milling. This difference indicates that FIB milling introduces damage that obviates the need for dislocation nucleation during subsequent deformation. A second effect of FIB milling is that it increased the surface hardness. Together, these effects could be the source of the size effects reported in the literature on micropillar tests.

2007-09-10

354

Transuranium isotopes production and their effect on the three-dimensional core calculation  

Energy Technology Data Exchange (ETDEWEB)

The operation of a nuclear power reactor necessarily implies the consumption or burnup of reactor fuel by fission and capture, which gives rise to a decrease in the reactivity of the reactor. The effect of americium formation on the criticality of a thermal power reactor using two types of fuel is studied. The three-dimensional core calculation is used to calculate the production of the transuranium isotopes and their effect on the effective multiplication factor (K[sub eff]). This effect cannot be neglected for thermal power reactors with UO[sub 2]-PuO[sub 2] fuel (3.11% after 70 weeks of operation). The effect of the transuranium isotopes on the K[sub eff] for a thermal power reactor with UO[sub 2] fuel is about 0.0018% and can be ignored. (author).

1993-02-01

355

Transuranium isotopes production and their effect on the three-dimensional core calculation  

International Nuclear Information System (INIS)

The operation of a nuclear power reactor necessarily implies the consumption or burnup of reactor fuel by fission and capture, which gives rise to a decrease in the reactivity of the reactor. The effect of americium formation on the criticality of a thermal power reactor using two types of fuel is studied. The three-dimensional core calculation is used to calculate the production of the transuranium isotopes and their effect on the effective multiplication factor (K_e_f_f). This effect cannot be neglected for thermal power reactors with UO_2-PuO_2 fuel (3.11% after 70 weeks of operation). The effect of the transuranium isotopes on the K_e_f_f for a thermal power reactor with UO_2 fuel is about 0.0018% and can be ignored. (author).

356

Psychological ownership and affective reaction: Emotional attachment process variables and the endowment effect  

British Library Electronic Table of Contents (United Kingdom)

This research proposes that the concept of emotional attachment, and specifically the independent constructs of psychological ownership and affective reaction, can help explain many of the endowment effect findings documented in the literature. We define these constructs and then test them across a set of nine studies in which we both replicate previous and generate new endowment effect findings, and then show that psychological ownership and affective reaction can mediate the effects. In doing so, we offer direct empirical support for the idea of emotional attachment as a driver of loss aversion while also providing practitioners and future endowment effect researchers with new insights about the psychological processes that underlie the endowment effect.

2011-01-01

357

Optical effects of fine-particle carbon on urban atmospheres  

Energy Technology Data Exchange (ETDEWEB)

The effects of fine-particle C, such as diesel soot, on the optical properties of urban haze in the visible wavelength range were explored to determine the dominant effects and to see if simple parameters (such as visual range in green) provide an adequate measure of these effects. It is known that fine-particle C absorbs more strongly in the blue than in the red, so that when it is mixed with a white pigment, the resulting gray can appear somewhat brown. The possibility of a similar effect in urban hazes was investigated, but found not to occur. When the sun is overhead, the near-horizon sky chromaticities caused by mixtures of fine-particle C and non-absorbing aerosol can also be produced by non-absorbing aerosols alone. It is shown that absorbing aerosol will darken the horizon sky, and a simple equation for the radiance of the horizon sky is derived. The effect of absorbing ...

1986-01-01

358

Numerical evaluation of effective unsaturated hydraulic properties for fractured rocks  

Energy Technology Data Exchange (ETDEWEB)

To represent a heterogeneous unsaturated fractured rock by its homogeneous equivalent, Monte Carlo simulations are used to obtain upscaled (effective) flow properties. In this study, we present a numerical procedure for upscaling the van Genuchten parameters of unsaturated fractured rocks by conducting Monte Carlo simulations of the unsaturated flow in a domain under gravity-dominated regime. The simulation domain can be chosen as the scale of block size in the field-scale modeling. The effective conductivity is computed from the steady-state flux at the lower boundary and plotted as a function of the averaging pressure head or saturation over the domain. The scatter plot is then fitted using van Genuchten model and three parameters, i.e., the saturated conductivity K{sub s}, the air-entry parameter {alpha}, the pore-size distribution parameter n, corresponding to this model are considered as the effective K{sub s}, ...

2009-01-01

359

Locally resonant acoustic metamaterials with 2D anisotropic effective mass density  

British Library Electronic Table of Contents (United Kingdom)

A two-dimensional (2D) lattice model with anisotropic resonant microstructures is found to provide an anisotropic band gap structure. A 2D continuum with anisotropic effective mass density is introduced to represent this lattice system. Two methods are proposed to derive the equivalent continuum. In the first method, the effective mass density of the equivalent continuum is obtained by matching the dispersion relations for harmonic waves propagating in the principal directions. The second approach employs an approximate estimation of the effective mass density by volume-averaging an effective mass that represents the resonant microstructure. For both equivalent continuum models, the effective mass density is frequency-dependent and may become negative in certain frequency ranges. Subsequen...

2011-01-01

360

Hepatoprotective and anti-hepatocarcinogenic effects of glycyrrhizin and matrine  

British Library Electronic Table of Contents (United Kingdom)

Matrine (Mat), a component extracted from Sophora flavescens Ait, has a wide spectrum of pharmacological effects. Glycyrrhizin (Gly), a major active constituent of licorice (Glycyrrhiza glabra) root, has various pharmacological effects. Gly and Mat are ancillary drugs used clinically in China for protection of liver function and treatment of tumors. However, habitual administration of Gly may cause adverse effects marked by the development of pseudohypercorticosteroidism. This work was designed to see whether combination use of Gly and Mat could offer better liver protective and anti-hepatocarcinogenic effects than Gly or Mat alone, and whether it could reduce the adverse effects of Gly alone by acetaminophen-induced hepatotoxicity, diethylnitrosamine-induced hepatocarcinogenesis, inductio...

2009-01-01

361

Field tests on partial embedment effects (embedment effect tests on soil-structure interaction)  

International Nuclear Information System (INIS)

A series of Model Tests of Embedment Effect on Reactor Buildings has been carried out by the Nuclear Power Engineering Corporation (NUPEC), under the sponsorship of the Ministry of International Trade and lndustry (MITI) of Japan. The nuclear reactor buildings are partially embedded due to conditions for the construction or building arrangement in Japan. It is necessary to verify the partial embedment effects by experiments and analytical studies in order to incorporate the effects in the seismic design. Forced vibration tests, therefore, were performed using a model with several types of embedment. Correlated simulation analyses were also performed and the characteristics of partial embedment effects on soil-structure interaction were evaluated. (author)

1993-08-15

362

Effective dose equivalent concept in radiopharmaceutical dosimetry  

Energy Technology Data Exchange (ETDEWEB)

The Effective Dose Equivalent Concept defined by the International Commission on Radiological Protection in 1977 considers the risk from irradiation including both hereditary and somatic effects. This paper will deal with the definition of a concept for somatic effects only, the somatically significant dose equivalent. This is defined as the dose equivalent which if received by every member of the population, would be expected to produce the same total somatic injury to the population as does the actual dose equivalent received by various individuals. The somatically effective dose equivalent for a particular radiopharmaceutical is the weighted sum of the average dose equivalent to various organs. The dose equivalent to various organs can be derived from an extended MIRD formalism also considering the rest of body excluding the source volumes and the re iden e times in total body and the target organs. ...

1981-06-01

363

Effective dose equivalent concept in radiopharmaceutical dosimetry  

International Nuclear Information System (INIS)

The Effective Dose Equivalent Concept defined by the International Commission on Radiological Protection in 1977 considers the risk from irradiation including both hereditary and somatic effects. This paper will deal with the definition of a concept for somatic effects only, the somatically significant dose equivalent. This is defined as the dose equivalent which if received by every member of the population, would be expected to produce the same total somatic injury to the population as does the actual dose equivalent received by various individuals. The somatically effective dose equivalent for a particular radiopharmaceutical is the weighted sum of the average dose equivalent to various organs. The dose equivalent to various organs can be derived from an extended MIRD formalism also considering the rest of body excluding the source volumes and the re iden e times in total body and the target organs. ...

364

Cost-effectiveness analysis for proposed effluent limitations guidelines and standards for the coastal subcategory of the oil and gas extraction point source category  

Energy Technology Data Exchange (ETDEWEB)

The analysis is submitted in support of the effluent limitations guidelines and standards for the Coastal Oil and Gas Industry. The report analyzes the cost-effectiveness of 10 regulatory options organized by three wastestreams. The document compares the total annualized cost incurred for each of the regulatory options within each wastestream to the corresponding effectiveness of that option in reducing the discharge of pollutants. Section Two discusses the cost-effectiveness methodology used and identifies the pollutants included in the analysis, presenting their toxic weighting factors and removal efficiencies. Section Three presents the results of the analysis. In Section Four, the cost-effectiveness values are compared to cost-effectiveness values for other promulgated rules. Appendix A presents data on pollutants, pollutant removals, annualized costs, and other, more detailed ...

1995-01-01

365

A hybrid solar desalination process of the multi-effect humidification dehumidification and basin-type unit  

British Library Electronic Table of Contents (United Kingdom)

This paper presents a hybrid solar desalination process of the multi-effect humidification dehumidification and the basin-type unit. The sketch of the hybrid solar desalination process is given. The solar vacuated tube collector is employed in the desalination system, multi-effect humidification dehumidification desalination (HDD) process is plotted according to pinch technology, and then the water rejected from multi-effect HDD process is reused to desalinate in a basin-type unit further. The gain output ratio (GOR) of this system will rise by 2?3 at least through reusing the rejected water. The research proves that the multi-effect HDD has much room to be improved. A hybrid solar desalination process of the multi-effect humidification dehumidification and the basin-type unit should be no...

2008-01-01

366

Health effects models for nuclear power plant accident consequence analysis. Modification of models resulting from addition of effects of exposure to alpha-emitting radionuclides: Revision 1, Part 2, Scientific bases for health effects models, Addendum 2  

Energy Technology Data Exchange (ETDEWEB)

The Nuclear Regulatory Commission (NRC) has sponsored several studies to identify and quantify, through the use of models, the potential health effects of accidental releases of radionuclides from nuclear power plants. The Reactor Safety Study provided the basis for most of the earlier estimates related to these health effects. Subsequent efforts by NRC-supported groups resulted in improved health effects models that were published in the report entitled {open_quotes}Health Effects Models for Nuclear Power Plant Consequence Analysis{close_quotes}, NUREG/CR-4214, 1985 and revised further in the 1989 report NUREG/CR-4214, Rev. 1, Part 2. The health effects models presented in the 1989 NUREG/CR-4214 report were developed for exposure to low-linear energy transfer (LET) (beta and gamma) radiation based on the best scientific information available at that time. Since the 1989 report was ...

1993-05-01

367

X-ray dose enhancement effects  

International Nuclear Information System (INIS)

A brief description of the physical process of dose enhancement effects produced by X-ray radiation on materials is given, with emphasis on the influence on electronic devices. The damages caused by X-ray radiation dose enhancement is more serious than that of #gamma#-ray with higher energy.

368

Using and Interpreting Adjusted NNT Measures in Biomedical Research  

UK PubMed Central (United Kingdom)

The number needed to treat (NNT) is a popular effect measure to present study results in biomedical research. NNTs were originally proposed to describe the absolute effect of a new treatment compared...Full Text Available

369

Using Multidetector Computed Tomography in a Swine Model to Assess the Effects of Sublingual Nitroglycerin and Intravenous Adenosine on Epicardial Coronary Arteries  

UK PubMed Central (United Kingdom)

This study examines the effects of intravenous infusion of adenosine and sublingual nitroglycerin on coronary angiograms obtained by current-generation multidetector computed tomography. We assessed...Full Text Available

2009-12-01

370

Uncovering the Mechanisms of Estrogen Effects on Hippocampal Function  

UK PubMed Central (United Kingdom)

Estrogens have direct effects on the brain areas controlling cognition. One of the most studied of these regions is the dorsal hippocampal formation, which governs the formation of spatial and...Full Text Available

2008-05-01

371

Toxic Effects of Linear Alkylbenzene Sulfonate on Metabolic Activity, Growth Rate, and Microcolony Formation of Nitrosomonas and Nitrosospira Strains  

UK PubMed Central (United Kingdom)

Strong inhibitory effects of the anionic surfactant linear alkylbenzene sulfonate (LAS) on four strains of autotrophic ammonia-oxidizing bacteria (AOB) are reported. Two Nitrosospira...Full Text Available

2001-06-01

372

The impact of water intake on energy intake and weight status: a systematic review  

UK PubMed Central (United Kingdom)

The effects of consuming water with meals rather than drinking no beverage or various other beverages remains under-studied. This systematic review of English language studies compared the effects...Full Text Available

2010-09-01

373

The effects of thiamin on lead metabolism: organ distribution of lead 203.  

UK PubMed Central (United Kingdom)

The effect of thiamin on the organ distribution of lead was evaluated in CD-1 mice exposed intragastrically or intraperitoneally to a single dose of lead acetate (100 micrograms) containing 100 microCi...Full Text Available

1992-07-01

374

The effects of an HIV project on HIV and non-HIV services at local government clinics in urban Kampala  

UK PubMed Central (United Kingdom)

BackgroundHIV/AIDS is a major public health concern in Uganda. There is widespread consensus that weak health systems hamper the effective provision of HIV/AIDS services. In recent...Full Text Available

375

The effective longitudinal dielectric constant for plasmas in inhomogeneous magnetic fields  

Scientific Electronic Library Online (English)

Abstract in english We present a detailed derivation of the effective dielectric constant to be used in the dispersion relation for electrostatic waves in the case of a plasma immersed in a inhomogeneous magnetic field, with inhomogeneity perpendicular to the direction of the magnetic field.

2004-09-01

376

The effect of maternal anthropometric characteristics and social factors on gestational age and birth weight in Sudanese newborn infants  

UK PubMed Central (United Kingdom)

BackgroundIn Africa low birth weight (LBW) (<2500 g), is the strongest determinant of infant morbidity and mortality. The aim of this study was to quantify the effect of...Full Text Available

377

The effect of lipopolysaccharide on bovine mammary macrophage function.  

UK PubMed Central (United Kingdom)

The effect of Escherichia coli lipopolysaccharide (LPS) on the expression of major histocompatibility complex (MHC) class II molecules by bovine mammary macrophages was examined. The ability of LPS-treated...Full Text Available

1991-07-01

378

The effect of diphenylhydantoin on thyroxine metabolism in man  

UK PubMed Central (United Kingdom)

The effect of 5,5′-diphenylhydantoin on thyroxine metabolism was examined in five normal volunteers. Intravenous injection of radiothyroxine was followed by a 10-12 day control and subsequent...Full Text Available

1970-06-01

379

The effect of an ?-globulin preparation and of polyribonuclease complexes on humoral antibody formation  

UK PubMed Central (United Kingdom)

The effects of bovine α-globulin (BAG), bovine-ribonuclease serum albumin (BSA-RNase) and polyribonuclease (poly-RNase) complexes on the primary response of rodents to sheep erythrocytes have...Full Text Available

1968-06-01

380

The Mechanism and the Magnitude of Flow Boiling Augmentation in Tubes with Discrete Surface Roughness Elements (III).  

Science.gov (United States)

Related to other research on the effectiveness of flow boiling heat transfer augmentation using various types of turbulators this investigation comprises a definitive study of the effect of large discrete roughness elements on heat transfer over the entir...

1972-01-01

381

The Effect of Reference Signals in a Visual Vigilance Task.  

Science.gov (United States)

The effect of reference signals on performance in a visual vigilance task was studied under three conditions. Reference signals were presented on the same display as the real signals. In condition 1 (control), no reference signals were displayed. Sugbject...

1969-01-01

382

The Effect of O2, H2O, and N2 on the Fatigue Crack Growth Behavior of an Alpha + Beta Titanium Alloy at 24 C and 177 C  

Science.gov (United States)

To study the effects of atmospheric species on the fatigue crack growth behavior of an a+B titanium

2001-01-01

383

The Effect of Live Classical Piano Music on the Vital Signs of Patients Undergoing Ophthalmic Surgery  

UK PubMed Central (United Kingdom)

ContextMusic and surgery.ObjectiveTo determine the effect of live classical piano music on vital signs of patients undergoing ophthalmic surgery.DesignRetrospective...Full Text Available

384

The Effect of Lindane Formulations on Tissue Residues in Barrows and on Stillbirths in Sows  

UK PubMed Central (United Kingdom)

The potential effect of lindane and its formulations on stillbirths and abortion in pregnant sows was investigated. One of four formulations of lindane were applied at five times the registered dosage...Full Text Available

1986-01-01

385

The Effect of Graded Recession and Anteriorization on Unilateral Superior Oblique Palsy  

UK PubMed Central (United Kingdom)

PurposeWe wanted to examine the effect of graded recession and anteriorization of the inferior oblique muscle on patients suffering from unilateral superior oblique palsy.MethodsInferior...Full Text Available

2006-09-01

386

The Effect of Different Timber Harvesting Techniques on Plethadontid Salamander Populations.  

Science.gov (United States)

This investigation will explore the effect that current timber extraction techniques have on plethadontid salamander populations in ... group selection, and two-age harvest. Broad scale timber extraction can d...

387

THE EFFECTS OF RESPONSE EFFORT ON SAFE PERFORMANCE BY THERAPISTS AT AN AUTISM TREATMENT FACILITY  

UK PubMed Central (United Kingdom)

The effects of response effort on safe behaviors (i.e., glove wearing, hand sanitizing, and electrical outlet replacement) exhibited by therapists at an autism treatment center were examined. Participants...Full Text Available

2010-01-01

388

Some aspects of the pharmacology of an homologous series of choline esters of fatty acids  

UK PubMed Central (United Kingdom)

The pharmacological effects of a series of fatty acid-choline esters have been studied on the isolated rabbit heart, the isolated guinea-pig ileum and the rat stomach. The effect changed with increasing...Full Text Available

1957-03-01

389

Short-term effects of tumor necrosis factor on energy and substrate metabolism in dogs.  

UK PubMed Central (United Kingdom)

In vivo short-term effects of recombinant human TNF-alpha on lipolysis, FFA flux, fat oxidation, triglyceride-fatty acid cycling, and glucose kinetics were evaluated with stable isotopic tracers and...Full Text Available

1993-06-01

390

Sexual differentiation of the zebra finch song system: potential roles for sex chromosome genes  

UK PubMed Central (United Kingdom)

BackgroundRecent evidence suggests that some sex differences in brain and behavior might result from direct genetic effects, and not solely the result of the organizational effects...Full Text Available

391

Sequential effects in two-choice reaction time tasks: Decomposition and synthesis of mechanisms  

UK PubMed Central (United Kingdom)

Performance on serial tasks is influenced by first- and higher-order sequential effects, respectively due to the immediately previous and earlier trials. As response-to-stimulus interval (RSI)...Full Text Available

2009-09-01

392

Seasonal and Annual Variation in Activity in Wild Male Meadow Voles (Microtus Pennsylvanicus).  

Science.gov (United States)

Project ZEUS was designed to characterize the effects of long-term gamma irradiation on free-ranging meadow voles, and to determine the lowest level of radiation at which biological effects are discernible in the population. Behavioural tests are consider...

1980-01-01

393

Role of surface degrees of freedom in grazing heavy ion collisions  

Energy Technology Data Exchange (ETDEWEB)

A survey is given of the influence of surface deformations on heavy ion reactions. Emphasis is put on the effect of zeropoint fluctuations in the entrance channel and on the effect on grazing collisions in terms of an imaginary part of the scattering potential.

1983-11-14

394

Role of surface degrees of freedom in grazing heavy ion collisions  

International Nuclear Information System (INIS)

A survey is given of the influence of surface deformations on heavy ion reactions. Emphasis is put on the effect of zeropoint fluctuations in the entrance channel and on the effect on grazing collisions in terms of an imaginary part of the scattering potential. (orig.).

395

Reproductive Success of Cavity-nesting Birds Breeding under High-voltage Powerlines  

Science.gov (United States)

... biological effects of electromagnetic fields (EMFs) produced by high-voltage transmission lines have come under intense scrutiny, mostly with respect ... biological effects of electromagnetic fields (EMFs...

396

Protective effects of hydroalcoholic extract from rhizomes of Cynodon dactylon (L.) Pers. on compensated right heart failure in rats  

UK PubMed Central (United Kingdom)

BackgroundThe rhizomes of Cynodon dactylon are used for the treatment of heart failure in folk medicine. In the present study, we investigated the effects of hydroalcoholic...Full Text Available

397

Project resumes: biological effects from electric fields associated with high-voltage transmission lines  

Energy Technology Data Exchange (ETDEWEB)

Abstracts of research projects are presented in the following areas: measurements and special facilities; cellular and subcellular studies; physiology; behavior; environmental effects; modeling, scaling and dosimetry; and high voltage direct current. (ACR)

1980-01-01

398

Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol  

UK PubMed Central (United Kingdom)

PurposeRadiation-induced heart disease (RIHD) is a severe side effect of thoracic radiotherapy. This study examined the effects of PTX and α-tocopherol on...Full Text Available

2008-09-01

399

Phase transitions in the soliton star model  

Energy Technology Data Exchange (ETDEWEB)

The aim of this paper is to obtain the effective potential of the non-topological soliton model at finite temperature with the assumption that the chemical potential {mu} of the system is different from zero and to analyse how the effective potential is influenced by changes in the chemical potential and temperature. (author)

1998-01-01

400

Pharmacologically Induced Hypogonadism and Sexual Function in Healthy Young Women and Men  

UK PubMed Central (United Kingdom)

Studies fail to find uniform effects of age-related or induced hypogonadism on human sexual function. We examined the effects of induced hypogonadism on sexual function in healthy men and women...Full Text Available

2009-02-01

401

One-Year Durability of the Effects of Cognitive Enhancement Therapy on Functional Outcome in Early Schizophrenia  

UK PubMed Central (United Kingdom)

Cognitive rehabilitation is an effective intervention for addressing cognitive impairments in patients with schizophrenia. Previous research has shown that the early application of Cognitive...Full Text Available

2010-07-01

402

On the temperature dependence of the level density parameter and its effect upon neutron evaporation spectra  

Energy Technology Data Exchange (ETDEWEB)

Effects associated with the temperature dependence of the level density parameter, a(T), are investigated in connection with neutron evaporation processes. Different approximations, for this temperature dependence, are compared for the case of neutron emission from the compound nucleus /sup 209/Pb.

1987-07-01

403

On the chiral effective meson-baryon Lagrangian at third order{sup *}  

Energy Technology Data Exchange (ETDEWEB)

We show that the recently constructed complete and ''minimal'' third-order meson-baryon effective chiral Lagrangian can be further reduced from 84 to 78 independent operators. (orig.)

2006-09-15

404

Near-infrared spectroscopy technique to evaluate the effects of red blood cell transfusion on tissue oxygenation  

UK PubMed Central (United Kingdom)

IntroductionThe aim of this study was to evaluate the effects of red blood cell (RBC) transfusions on muscle tissue oxygenation, oxygen metabolism and microvascular reactivity in...Full Text Available

2009-01-01

405

Microsoft Word - VAT reduction final report.doc  

Wastenet

3 Effectiveness of reduced VAT rates 1.4 Indirect effects 1.5 Administrative and compliance costs ...3 United Kingdom 31 ... 3.Case study: Central heating boilers

406

Long-term effects of inhaled uranyl nitrate in rats  

International Nuclear Information System (INIS)

Rats were exposed to aerosols of "2"3"3U and "2"3"2U nitrate in a study of the long-term biological effects. Preliminary radiation dose estimates show lung > skeleton > kidney in each dose group.

1977-05-01

407

Localization and Toxic Effects of Cadmium, Copper, and Uranium in Azolla1  

UK PubMed Central (United Kingdom)

The storage and distribution of copper, cadmium, and uranium and their effects on ionic contents in roots and shoots of Azolla filiculoides has been studied by x-ray microanalysis....Full Text Available

1988-09-01

408

Immediate and residual effects in man of the metabolites of diazepam  

UK PubMed Central (United Kingdom)

1 Immediate and residual effects of diazepam and its metabolites on visuomotor co-ordination have been studied in man. Performance was observed from 10.0-16.0 h after overnight ingestion...Full Text Available

1978-10-01

409

Healthy worker effect in the total Finnish population.  

UK PubMed Central (United Kingdom)

The selection due to the "healthy worker effect" was estimated from a random sample of the total Finnish population. The sample of 20 000 people was followed for changes in occupations from 1960 to...Full Text Available

1980-05-01

410

Health related virtual communities and electronic support groups: systematic review of the effects of online peer to peer interactions  

UK PubMed Central (United Kingdom)

Objective To compile and evaluate the evidence on the effects on health and social outcomes of computer based peer to peer communities and electronic self support groups, used by people...Full Text Available

2004-05-15

411

Health effects of air pollutants: sulfuric acid, the old and the new.  

UK PubMed Central (United Kingdom)

Data from exposure of experimental animals and human subjects to sulfuric acid presents a consistent picture of its toxicology. Effects on airway resistance in asthmatic subjects were well predicted...Full Text Available

1989-05-01

412

H-1152 Effects on Intraocular Pressure and Trabecular Meshwork Morphology of Rat Eyes  

UK PubMed Central (United Kingdom)

AbstractPurposeThe aim of this study was to elucidate the effects of the Rho-kinase inhibitor, H-1152, on cultured human trabecular meshwork (HTM) cells, TM morphology,...Full Text Available

2008-08-01

413

Guidelines on exchangers  

Energy Technology Data Exchange (ETDEWEB)

Experience has shown that a list of tips provides designers and engineers with an effective guide in their areas of duties and concern. This list contains new and rare information on heat exchangers and heat recovery systems. The information presented can be used effectively with personal computers and pocket calculators and also conveniently translated into computer programs and nomographs.

1985-08-01

414

Geothermal status report  

International Nuclear Information System (INIS)

This article examines the effects of competition of geothermal energy production with other technologies. The topics of the article include near-term market growth, cause for cautious optimism, limits to development of geothermal energy production, economic arguments for development of geothermal power plants, the effects of a competitive market on industry survival.

415

Genetic association between the COMT genotype and urinary levels of tea polyphenols and their metabolites among daily green tea drinkers  

UK PubMed Central (United Kingdom)

Available in vitro and animal studies have shown cancer protective effects of tea polyphenols. Recent study suggests a greater protective effect of green tea intake on breast cancer...Full Text Available

416

Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice  

UK PubMed Central (United Kingdom)

Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are important factors both in aging and in the development of cancer. It is possible that the life-prolonging effects...Full Text Available

417

Functional and morphological effects of laser-induced ocular hypertension in retinas of adult albino Swiss mice  

UK PubMed Central (United Kingdom)

PurposeTo investigate the effects of laser photocoagulation (LP)-induced ocular hypertension (OHT) on the survival and retrograde axonal transport of retinal ganglion cells (RGC),...Full Text Available

418

Flucton model with scaling breaking: EMC effect and lepton pair production on nuclei  

International Nuclear Information System (INIS)

The EMS effect is explained in the flucton model as a consequence of scale invariance violation. Nontrivial behaviour of the ratio between structural functions and production cross sections for lepton pairs for different nuclei at x > 1 is predicted.

419

Female rats display dose-dependent differences to the rewarding and aversive effects of nicotine in an age-, hormone-, and sex-dependent manner  

UK PubMed Central (United Kingdom)

IntroductionThe objective of this study was to examine age-, hormone-, and sex-dependent differences to the behavioral effects of nicotine using place-conditioning...Full Text Available

2009-10-01

420

FURTHER EVALUATION OF RESPONSE INTERRUPTION AND REDIRECTION AS TREATMENT FOR STEREOTYPY  

UK PubMed Central (United Kingdom)

The effects of 2 forms of response interruption and redirection (RIRD)—motor RIRD and vocal RIRD—were examined with 4 boys with autism to evaluate further the effects of this intervention...Full Text Available

2011-01-01

421

Exposure to nitroaromatic explosives and health effects during disposal of military waste  

UK PubMed Central (United Kingdom)

Aims: To investigate the exposure to dinitrotoluene (DNT) and trinitrotoluene (TNT) and the resulting effects in workers which occur during the disposal of military waste. Methods:...Full Text Available

2003-07-01

422

Evaluating noncancer effects of trichloroethylene: dosimetry, mode of action, and risk assessment.  

UK PubMed Central (United Kingdom)

Alternatives for developing chronic exposure limits for noncancer effects of trichloroethylene (TCE) were evaluated. These alternatives were organized within a framework for dose-response assessment--exposure:dosimetry...Full Text Available

2000-05-01

423

Estimation of effective population sizes from data on genetic markers  

UK PubMed Central (United Kingdom)

The effective population size (Ne) is an important parameter in ecology, evolutionary biology and conservation biology. It is, however, notoriously difficult to estimate,...Full Text Available

2005-07-29

424

Erythrocyte transketolase activity in suspected cases of Leigh's disease, or subacute necrotising encephalomyelopathy.  

UK PubMed Central (United Kingdom)

Erythrocyte transketolase activity and the effect of adding thiamine pyrophosphate (% thiamine pyrophosphate effect) were measured in 111 subjects suspected to suffer from Leigh's disease (subacute...Full Text Available

1980-10-01

425

Environmental Effects and Energy Efficiency in Building Design: A Green Building Approach. Part 2. Basic Data for Environmental Effects.  

Science.gov (United States)

The development of comfort in buildings throughout the centuries was influenced by the demand for progress, wealth and innovation in various respects. At present, it seems that progress may only be possible by taking into account the environment and creat...

1993-01-01

426

Endocrine and Neurochemical Effects of 3,4-Methylenedioxymethamphetamine and Its Stereoisomers in Rhesus Monkeys  

UK PubMed Central (United Kingdom)

3,4-Methylenedioxymethamphetamine (MDMA) is an amphetamine derivative that elicits complex biological effects in humans. One plausible mechanism for this phenomenon is that racemic MDMA is composed...Full Text Available

2010-08-01

427

Employing Kirkpatrick's Evaluation Framework to Determine the Effectiveness of Health Information Management Courses and Programs  

UK PubMed Central (United Kingdom)

Evaluation of the impact and effectiveness of courses is necessary so that strengths and weaknesses can be identified and improvements made. This article uses Kirkpatrick's evaluation framework to present...Full Text Available

428

Electronic spectra of semiconductor nanocrystals  

Energy Technology Data Exchange (ETDEWEB)

Semiconductor nanocrystals smaller than the bulk exciton show substantial quantum confinement effects. Recent experiments including Stark effect, resonance Raman, valence band photoemission, and near edge X-ray adsorption will be used to put together a picture of the nanocrystal electronic states.

1993-12-31

429

Electron spin resonance studies of radiation effects in biological materials. An assessment of current and future research  

Energy Technology Data Exchange (ETDEWEB)

Electron spin resonance spectroscopy can provide a powerful approach to the study of radiation effects in biological materials. This memorandum gives an overview of current and future research. (author).

1987-06-01

430

Efficacy of standard glucose-based and reduced-osmolarity maltodextrin-based oral rehydration solutions: effect of sugar malabsorption.  

UK PubMed Central (United Kingdom)

Previously we reported that standard oral rehydration salts (ORS) solution is not as effective as a reduced-osmolarity glucose-based ORS for the treatment of children with acute noncholera diarrhoea:...Full Text Available

1996-01-01

431

Effects of oxygenated blending compounds on emissions from a turbo-charged direct injection diesel engine  

Energy Technology Data Exchange (ETDEWEB)

An experimental investigation was conducted to evaluate the effect of three different oxygenated compounds, diglyme, diethyl maleate and dibutyl maleate, on emissions from a Volkswagen 1.9 litre, turbocharged, direct injection diesel engine. Sampling was performed using a mini-dilution tunnel technique to obtain particulate matter and a Fourier transform infrared (FTIR) spectrometer for gaseous emissions. The particulate samples were analysed using thermal analysis and Soxhlet extraction to determine the fraction of volatile and soluble organic material respectively. All three oxygenated compounds were found to be effective at reducing particulate emissions, with the maleate compounds being more effective overall than the diglyme. Analysis of the relative contributions of changes in the soot and soluble organic fraction (SOF) to the reduction of particulate matter indicated that, for diethyl maleate and diglyme, reductions ...

2000-02-01

432

Effects of gonadotrophin releasing hormone on reproductive performance of dairy cows with retained placenta.  

UK PubMed Central (United Kingdom)

The effects of gonadotrophin releasing hormone (GnRH) on the reproductive performance of dairy cows with retained placenta were studied. Three hundred and seventy-eight cows diagnosed as having retained...Full Text Available

1984-10-01

433

Effects of gender, age, diabetes mellitus and renal and hepatic impairment on tadalafil pharmacokinetics  

UK PubMed Central (United Kingdom)

AimsTo evaluate the effects of gender, age, diabetes mellitus, renal and hepatic impairment on tadalafil pharmacokinetics and tolerability.MethodsSix...Full Text Available

2007-01-01

434

Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep.  

UK PubMed Central (United Kingdom)

The effects of Escherichia coli endotoxin on lung mechanics, hemodynamics, gas exchange, and lung fluid and solute exchange were studied in 12 chronically instrumented unanesthetized sheep. A possible...Full Text Available

1983-07-01

435

Effects of bovine leukemia virus infection on production and reproduction in dairy cattle.  

UK PubMed Central (United Kingdom)

The purpose of this study was to determine the effects of bovine leukemia virus (BLV) infection on production, reproduction and longevity in dairy cattle. The study population was a commercial Holstein...Full Text Available

1992-10-01

436

Effects of biotin supplementation on serum biotin levels and physical properties of samples of solar horn of Holstein cows  

UK PubMed Central (United Kingdom)

AbstractEffects of dietary biotin supplementation on serum biotin levels and physical properties of sole horn of 40 Holstein cows were evaluated. The mean serum biotin level in biotin-supplemented...Full Text Available

2004-04-01

437

Effects of ammonia and hydrogen sulfide on physical and biochemical properties of the claw horn of Holstein cows  

UK PubMed Central (United Kingdom)

The effects of ammonia and hydrogen sulfide on the physical and biochemical properties of the claw horn of Holstein cows were evaluated. Significant (P < 0.05, 0.01) decreases...Full Text Available

2009-01-01

438

Effects of acute dieldrin exposure on neurotransmitters and global gene transcription in largemouth bass (Micropterus salmoides) hypothalamus  

UK PubMed Central (United Kingdom)

Exposure to dieldrin induces neurotoxic effects in the vertebrate CNS and disrupts reproductive processes in teleost fish. Reproductive impairment observed in fish by dieldrin is likely the...Full Text Available

2010-08-01

439

Effects of a community mental health service on the practice and attitudes of general practitioners.  

UK PubMed Central (United Kingdom)

Recent years have seen closer links developing between general practitioners and mental health specialists. A study was undertaken in Manchester to determine the effects of a new community mental health...Full Text Available

1993-12-01

440

Effects of Sildenafil and Tadalafil on Intraocular Pressure in Sheep: Implications for Aqueous Humor Dynamics  

UK PubMed Central (United Kingdom)

Purpose.To determine the effects of vasodilators on intraocular pressure (IOP) and the protein content of sheep aqueous humor (AH), because the vasodilators may increase fluid leakage...Full Text Available

2010-06-01

441

Effects of Semantic Context and Feedback on Perceptual Learning of Speech Processed through an Acoustic Simulation of a Cochlear Implant  

UK PubMed Central (United Kingdom)

The effect of feedback and materials on perceptual learning was examined in normal hearing listeners exposed to cochlear implant simulations. Generalization was most robust when feedback paired...Full Text Available

2010-02-01

442

Effects of Perfluorocarbons on surfactant exocytosis and membrane properties in isolated alveolar type II cells  

UK PubMed Central (United Kingdom)

BackgroundPerfluorocarbons (PFC) are used to improve gas exchange in diseased lungs. PFC have been shown to affect various cell types. Thus, effects on alveolar type II (ATII) cells...Full Text Available

2010-01-01

443

Effects of Naja nivea venom on nerve, cardiac and skeletal muscle activity of the frog  

UK PubMed Central (United Kingdom)

1. The effects of 1 mg/ml whole Naja nivea (Cape cobra) venom, and of three different toxins isolated from it, on spinal reflex excitability and cardiac and skeletal muscle activity...Full Text Available

1973-03-01

444

Effects of Intrathecal Baclofen on Perceived Sexual Functioning in Men With Spinal Cord Injury  

UK PubMed Central (United Kingdom)

Background/Objective:Reports in the literature suggest that administration of intrathecal baclofen to control spasticity may have deleterious effects on erectile function...Full Text Available

2008-01-01

445

Effects of Human Adipose-derived Stem Cells on Cutaneous Wound Healing in Nude Mice  

UK PubMed Central (United Kingdom)

BackgroundDespite numerous treatments available for deteriorated cutaneous wound healing such as a diabetic foot, there is still the need for more effective therapy. Adipose-derived...Full Text Available

2011-05-01

446

Effects of Daily Morphine Administration and Deprivation on Choice and Demand for Remifentanil and Cocaine in Rhesus Monkeys  

UK PubMed Central (United Kingdom)

Choice procedures have indicated that the relative reinforcing effectiveness of opioid drugs increases during opioid withdrawal. The demand curve, an absolute measure of reinforcer value, has not been...Full Text Available

2011-01-01

447

Effects of Cycling Temperatures on Fiber Metabolism in Cultured Cotton Ovules 1  

UK PubMed Central (United Kingdom)

The effects of temperature on rates of cellulose synthesis, respiration, and long-term glucose uptake were investigated using cultured cotton ovules (Gossypium hirsutum L. cv Acala...Full Text Available

1992-10-01

448

Effects of Age on Optical Coherence Tomography Measurements of Healthy Retinal Nerve Fiber Layer, Macula and Optic Nerve Head  

UK PubMed Central (United Kingdom)

PurposeTo determine the effects of age on global and sectoral peripapillary retinal nerve fiber layer (RNFL), macular thicknesses and optic nerve head (ONH) parameters...Full Text Available

2009-06-01

449

Effectiveness of Manual Physical Therapy for Painful Shoulder Conditions: A Systematic Review  

UK PubMed Central (United Kingdom)

Multiple disease-specific systematic reviews on the effectiveness of physical therapy intervention for shoulder dysfunction have been inconclusive. To date, there have been two systematic reviews that...Full Text Available

2009-01-01

450

Effective Reduced Diffusion-Models: A Data Driven Approach to the Analysis of Neuronal Dynamics  

UK PubMed Central (United Kingdom)

We introduce in this paper a new method for reducing neurodynamical data to an effective diffusion equation, either experimentally or using simulations of biophysically detailed models. The dimensionality...Full Text Available

2009-12-01

451

Effect of structured postgraduate medical education on the care of patients with diabetes.  

UK PubMed Central (United Kingdom)

BACKGROUND. Diabetes can be effectively treated and monitored in general practice. Postgraduate medical education at a local level is required to support this strategic shift of medical care from hospital...Full Text Available

1995-03-01

452

Effect of pH and Temperature on Denitrification Gene Expression and Activity in Pseudomonas mandelii?  

UK PubMed Central (United Kingdom)

Pseudomonas mandelii liquid cultures were studied to determine the effect of pH and temperature on denitrification gene expression, which was quantified by quantitative reverse transcription-PCR....Full Text Available

2009-06-01

453

Effect of oxygen and oxidizing ions on denting corrosion  

International Nuclear Information System (INIS)

Information is presented concerning solute concentration in a porous layer; solute concentration in a packed crevice; corrosion of a packed carbon steel crevice in NaCl-O"2 solutions; and effect of copper on corrosion in NaCl-O"2 solutions.

1983-01-01

454

Effect of misonidazole pretreatment on nitrogen mustard-induced DNA cross-linking in mouse tissues in vivo.  

UK PubMed Central (United Kingdom)

In the present study we have used the alkaline elution technique to study the effect of misonidazole (MISO) on the initial amount of DNA cross-linking in various normal and neoplastic tissues of C3H...Full Text Available

1984-12-01

455

Effect of mineral compounds in phosphoric acid polluted by sulfide ions on corrosion of nickel  

Energy Technology Data Exchange (ETDEWEB)

The inhibiting effects of two mineral compounds on corrosion of nickel in phosphoric acid (H[sub 3]PO[sub 4]) polluted by sulfide ions (S[sup 2[minus

1999-06-01

456

Effect of long-term caloric restriction on oxygen consumption and body temperature in two different strains of mice  

UK PubMed Central (United Kingdom)

The hypothesis, that a decrease in metabolic rate mediates the life span prolonging effect of caloric restriction (CR), was tested using two strains of mice, one of which, C57BL/6, exhibits...Full Text Available

2007-10-01

457

Effect of lead on erythrocyte membranes.  

UK PubMed Central (United Kingdom)

The effect of blood lead on erythrocyte membrane proteins was studied in 28 workers from a scrap lead refining factory and in 18 controls working in railway construction. Sodium dodecyl sulphate-polyacrylamide...Full Text Available

1983-05-01

458

Effect of household and village characteristics on financial catastrophe and impoverishment due to health care spending in Western and Central Rural China: A multilevel analysis  

UK PubMed Central (United Kingdom)

ObjectiveThe study aimed to examine the effect of household and community characteristics on financial catastrophe and impoverishment due to health payment in Western and Central...Full Text Available

459

Effect of dietary monosodium glutamate on trans fat-induced nonalcoholic fatty liver disease  

UK PubMed Central (United Kingdom)

The effects of dietary monosodium glutamate (MSG) on trans-fatty acid (TFA)-induced nonalcoholic fatty liver disease (NAFLD) are addressed in an animal model. We used Affymetrix microarray...Full Text Available

2009-08-01

460

Effect of dietary green tea extract and aerosolized difluoromethylornithine during lung tumor progression in A/J strain mice  

UK PubMed Central (United Kingdom)

Chemoprevention strategies to prevent the development of lung cancer in at-risk individuals are a key component in disease management. In addition to being highly effective, an ideal chemopreventive...Full Text Available

2008-08-01

461

Effect of capsaicin-sensitive sensory nerves on plasma glucose and catecholamine levels during 2-deoxyglucose-induced stress in conscious rats.  

UK PubMed Central (United Kingdom)

1. Sensory fibres innervate the adrenal medulla but their function is not known. In this paper we have studied the effect of capsaicin-sensitive sensory fibres on the adrenal catecholamine (CA) response...Full Text Available

1990-07-01

462

Effect of association processes on polymerization of N-[3-(dimethylamino)propyl]methacrylamide salts in aqueous solutions  

British Library Electronic Table of Contents (United Kingdom)

The effect of associative interactions of monomers and propagating macroradicals in homopolymerization of N-[3-(dimethylamino)propyl]methacrylamide salts and their copolymerization with acrylonitrile and acrylamide in aqueous solution was studied.

2010-01-01

463

Effect of Wastewater Treatment Plant Effluent on Microbial Function and Community Structure in the Sediment of a Freshwater Stream with Variable Seasonal Flow?  

UK PubMed Central (United Kingdom)

We investigated the effects of wastewater treatment plant (WWTP) discharge on the ecology of bacterial communities in the sediment of a small, low-gradient stream in South Australia. The quantification...Full Text Available

2008-05-01

464

Effect of Protein Binding on the Pharmacological Activity of Highly Bound Antibiotics?  

UK PubMed Central (United Kingdom)

During antibiotic drug development, media are frequently spiked with either serum/plasma or protein supplements to evaluate the effect of protein binding. Usually, previously reported serum or plasma...Full Text Available

2008-11-01

465

Effect of Preslaughter Events on Prevalence of Campylobacter jejuni and Campylobacter coli in Market-Weight Turkeys  

UK PubMed Central (United Kingdom)

The effects of events which occur prior to slaughter, such as loading, transport, and holding at an abattoir, on the prevalence of Campylobacter species, including Campylobacter...Full Text Available

2005-06-01

466

Effect of Peroxisome Proliferator-Activated Receptor Gamma Agonist (Pioglitazone) and Methotrexate on Disease Activity in Rheumatoid Arthritis (Experimental and Clinical Study)  

UK PubMed Central (United Kingdom)

Objective:To investigate the combined effect of both pioglitazone and methotrexate on disease activity of rheumatoid arthritis in a biphasic study; experimental and clinical.Methods:Experimentally:...Full Text Available

467

Effect of Particle Size on Compaction of Materials with Different Deformation Mechanisms with and without Lubricants  

UK PubMed Central (United Kingdom)

This work investigates the effect of excipient particle size on compaction properties of brittle, plastic and viscoelastic materials with and without added lubricants. Sieve cuts of Microcrystalline...Full Text Available

468

Effect of Length of Time before Incorporation on Survival of Pathogenic Bacteria Present in Livestock Wastes Applied to Agricultural Soil  

UK PubMed Central (United Kingdom)

In response to reports that the contamination of food can occur during the on-farm primary phase of food production, we report data that describes a possible cost-effective intervention measure. The...Full Text Available

2004-09-01

469

Effect of Heat Treatment on Some Mechanical Properties of Laminated Window Profiles Manufactured Using Two Types of Adhesives  

UK PubMed Central (United Kingdom)

The mechanical properties of laminated window profiles manufactured using two types of adhesives were determined. The objective of this study is to evaluate the effects of heat treatment on some mechanical...Full Text Available

470

Effect of Feeding Cows Genetically Modified Maize on the Bacterial Community in the Bovine Rumen?  

UK PubMed Central (United Kingdom)

Rumen-cannulated cows (n = 4) were fed successively silage made from either conventional or genetically modified (GM) maize. Results revealed no effects of GM maize on the dynamics...Full Text Available

2007-12-01

471

Effect of Anionic Salt and Highly Fermentable Carbohydrate Supplementations on Urine pH and on Experimentally Induced Hypocalcaemia in Cows  

UK PubMed Central (United Kingdom)

The objective of this experiment was to determine the effect of dietary grain on calcium homeostasis. Six rumen-fistulated dairy cows with 3 or more previous lactations and no history of parturient...Full Text Available

2004-01-01

472

Effect of #gamma#-irradiation on relaxation properties of sealants on organosilicon rubber base  

International Nuclear Information System (INIS)

The dielectrical properties of organosilicon sealants have been studied in the wide range of temperatures in the low and radio frequencies range. The effect of thermal treatment and #gamma#-irradiation on these properties is discussed.

473

Ecological relevance of air pollution abatement measures as a decision aid  

Energy Technology Data Exchange (ETDEWEB)

Air pollution abatement measures are not an end in themselves, and undesirable side effects should be taken into account. The proposed emission index takes into account the total emissions caused by a technical project as well as the effects of the individual pollutants.

1983-01-01

474

EFFECT OF THE DIGENEAN PARASITE PROTEROMETRA MACROSTOMA ON HOST MORPHOLOGY IN THE FRESHWATER SNAIL ELIMIA LIVESCENS  

Science.gov (United States)

... 1984; Martin-Mora et al., 1995), and parasitism (Rothschild and Rothschild, 1939; Pesigan et al., 1958; Moose, 1963; Pan, ... effects of digeneans are variable; they may enhance (Rothschild and Rothschild...

475

DISPERSION TOLERANCE CALCULATION FOR NSLS-II.  

Energy Technology Data Exchange (ETDEWEB)

In this paper we discuss the effect on the emittance of the residual dispersion in the insertion devices. The dispersion in the straights could be generated by the lattice error, trim dipole, and insertion device. The effect on the emittance is examined, and the dispersion tolerances are given for the NSLS-11.

2007-06-25

476

Cost-Effectiveness Analysis of Proposed Effluent Limitations Guidelines and Standards for the Pesticide Manufacturing Industry.  

Science.gov (United States)

The report analyzes the cost-effectiveness of two alternative regulatory options: A Treated Discharge Option and a Zero Discharge Option. The report compares the total annualized cost incurred for each of the two regulatory options to the corresponding ef...

1992-01-01

477

Cost-Effectiveness Analysis of Proposed Effluent Limitations Guidelines and Standards for the Centralized Waste Treatment Industry.  

Science.gov (United States)

This analysis, submitted in support of proposed effluent limitations guidelines and standards for the centralized waste treatment (CWT) industry, investigates the cost-effectiveness of 24 regulatory options, representing all possible combinations of nine ...

1995-01-01

478

Comparison of the Maturation of the Adrenergic and Serotonergic Neurotransmitter Systems in the Brain: Implications for Differential Drug Effects on Juveniles and Adults  

UK PubMed Central (United Kingdom)

Our understanding of the development of neurotransmitter systems in the central nervous system has increased greatly over the past three decades and it has become apparent that drug effects...Full Text Available

2007-04-15

479

Comparative analysis of cis-regulation following stroke and seizures in subspaces of conserved eigensystems  

UK PubMed Central (United Kingdom)

BackgroundIt is often desirable to separate effects of different regulators on gene expression, or to identify effects of the same regulator across several systems. Here, we focus...Full Text Available

480

Characterization of the stimulatory effect of high-fat diets on peroxisomal beta-oxidation in rat liver.  

UK PubMed Central (United Kingdom)

1. The effect on rat liver peroxisomal beta-oxidation of feeding diets containing various amounts of dietary oils was investigated. With increasing amounts (5-25%, w/w) of soya-bean oil an apparent,...Full Text Available

1982-08-15

481

Changes in health utilities and health-related quality of life over 12 months following radical prostatectomy  

UK PubMed Central (United Kingdom)

Introduction:Although radical prostatectomy (RP) is an effective treatment for prostate cancer, it has potentially deleterious effects on health-related quality of life (HRQoL)....Full Text Available

2009-12-01

482

CDDO-Me: A Novel Synthetic Triterpenoid for the Treatment of Pancreatic Cancer  

UK PubMed Central (United Kingdom)

Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal human malignancy with dismal prognosis and few effective therapeutic options. Novel agents that are safe and effective are urgently...Full Text Available

2010-12-01

483

Biomarkers Signal Contaminant Effects on the Organs of English Sole (Parophrys vetulus) from Puget Sound  

UK PubMed Central (United Kingdom)

Fish living in contaminated environments accumulate toxic chemicals in their tissues. Biomarkers are needed to identify the resulting health effects, particularly focusing on early changes at a subcellular...Full Text Available

2006-06-01

484

Benzyl carbamyl analogue of lignocaine: vasodepressor mechanism of action.  

Science.gov (United States)

1. The benzyl carbamyl analogue of lignocaine [2-(diethylaminoacetamido)-3-carbamyl-4-methyl-5-benzylpyrrole] at an intravenous dose of 4 mg/kg caused a blood pressure decrease of 54 mmHg. 2. A greater hypotensive effect was observed in hypertensive compared to normotensive animals. Anaesthesia magnified the vasodepressor effect in both groups. 3. The analogue did not possess centrally-mediated effects on blood pressure but exerted its hypotensive effect via a peripheral mechanism. 4. The analogue produced a relaxant effect on intestinal and vascular smooth muscle while exerting minimal effects on muscarinic, sympathetic, or ganglionic nicotinic receptors. 5. The analogue exhibited less cardiac depressant action on left ventricular rate (dp/dt) and force of contraction than lignocaine. 6. Lethal effects for the analogue were first observed ...

485

Attenuation of Cocaine's Reinforcing and Discriminative Stimulus Effects via Muscarinic M1 Acetylcholine Receptor StimulationS?  

UK PubMed Central (United Kingdom)

Muscarinic cholinergic receptors modulate dopaminergic function in brain pathways thought to mediate cocaine's abuse-related effects. Here, we sought to confirm and ...Full Text Available

2010-01-01

486

Assessing and Compensating for Zero-lag Correlation Effects in Time-lagged Granger Causality Analysis of fMRI  

UK PubMed Central (United Kingdom)

Effective connectivity in brain networks can be studied using Granger causality analysis which is based on temporal precedence, while functional connectivity is usually derived using zero-lag...Full Text Available

2010-06-01

487

An argument for the chicken embryo as a model for the developmental toxicological effects of the polyhalogenated aromatic hydrocarbons (PHAHs)  

Energy Technology Data Exchange (ETDEWEB)

This article will present the argument that the chicken embryo is especially appropriate as an animal model for studying the mechanism of the developmental toxicological effects of the polyhalogenated aromatic hydrocarbons (PHAHs). The PHAHs are a group of toxicologically related compounds including, in part, the polychlorinated dibenzodioxins, dibenzofurans and biphenyls. The chicken (Gallus gallus) embryo is relatively sensitive to the toxicological effects of the PHAHs being approximately two orders of magnitude more sensitive than the mature bird. The chicken embryo has been used to demonstrate general toxicological teratogeneicity, hepatotoxicity and neurotoxicity. Many of these effects, or analogous effects, have also been observed in mammals and fish. Thus, most animals appear to respond to the PHAHs with a similar toxicological profile, indicating that many of the biomarkers used for the PHAHs ...

1996-12-31

488

Amorphigenin inhibits Osteoclast differentiation by suppressing c-Fos and nuclear factor of activated T cells  

UK PubMed Central (United Kingdom)

Among the several rotenoids, amorphigenin is isolated from the leaves of Amopha Fruticosa and it is known that has anti-proliferative effects and anti-cnacer effects in many cell types....Full Text Available

2010-12-01

489

Actual and Potential Effects of Medical Resident Coverage on Reimbursement for Inpatient Visits by Attending Physicians  

UK PubMed Central (United Kingdom)

CONTEXTThe impact of residents on hospital finance has been studied; there are no data describing the economic effect of residents on attending physicians.OBJECTIVEIn...Full Text Available

2002-06-01

490

Access Intervention in an Integrated, Prepaid Group Practice: Effects on Primary Care Physician Productivity  

UK PubMed Central (United Kingdom)

ObjectiveTo estimate the joint effect of a multifaceted access intervention on primary care physician (PCP) productivity in a large, integrated prepaid group practice.Data...Full Text Available

2008-10-01

491

ANTITUMOR ACTIVITY OF HYALURONIC ACID SYNTHESIS INHIBITOR 4-METHYLUMBELLIFERONE IN PROSTATE CANCER CELLS  

UK PubMed Central (United Kingdom)

4-methylumbelliferone (4-MU) is a hyaluronic acid (HA) synthesis inhibitor with anticancer properties; the mechanism of its anticancer effects is unknown. We evaluated the effects of 4-MU on...Full Text Available

2010-04-01

492

AN ANALYSIS OF THE RELATIONSHIP BETWEEN SOLUBILITY AND STIMULATING EFFECT IN TARSAL CHEMORECEPTION  

UK PubMed Central (United Kingdom)

The rejection thresholds of the blowfly Phormia regina Meigen for a selected series of substituted aliphatic hydrocarbons have been determined and an analysis made of the effect on...Full Text Available

1950-05-20

493

A2e mediated phototoxic effects of endoilluminators  

UK PubMed Central (United Kingdom)

AimsTo compare the theoretical retinal threshold time for endoilluminators and experimental phototoxic effect using A2e laden retinal pigment epithelial (RPE) cells.MethodsThe...Full Text Available

2006-02-01

494

A tool to balance benefit and harm when deciding about adjuvant therapy  

UK PubMed Central (United Kingdom)

Adjuvant therapy aims to prevent outgrowth of residual disease but can induce serious side effects. Weighing conflicting treatment effects and communicating this information with patients is not elementary....Full Text Available

2009-03-24

495

A field study on the effects of dietary monensin on milk production and milk composition in dairy cows  

UK PubMed Central (United Kingdom)

The objectives of this study were to quantify the effect of 16 ppm of dietary monensin on milk production and composition of dairy cows, and to investigate factors having a potential impact on this...Full Text Available

2010-04-01

496

A Review of the Pathophysiology and Novel Treatments for Erectile Dysfunction  

UK PubMed Central (United Kingdom)

Erectile dysfunction (ED) affects up to 50% of men between the ages of 40 and 70. Treatment with PDE-5 inhibitors is effective in the majority of men with ED. However, PDE-5 inhibitors are not effective...Full Text Available

2010-01-01

497

A Murine Model to Study the Antibacterial Effect of Copper on Infectivity of Salmonella Enterica Serovar Typhimurium  

UK PubMed Central (United Kingdom)

This study investigated the effect of copper as an antibacterial agent on the infectivity of Salmonella enterica serovar Typhimurium. Mice were infected orally with a standardized dose...Full Text Available

2011-01-01

498

A Motivation-Focused Weight Loss Maintenance Program is an Effective Alternative to a Skill-Based Approach  

UK PubMed Central (United Kingdom)

ObjectiveMaintaining weight loss is a major challenge in obesity treatment. Individuals often indicate that waning motivation prompts cessation of effective weight...Full Text Available

2011-02-01

499

A Double Blind, Placebo-Controlled, Randomized Crossover Study of the Acute Metabolic Effects of Olanzapine in Healthy Volunteers  

UK PubMed Central (United Kingdom)

Background and RationaleAtypical antipsychotics exhibit metabolic side effects including diabetes mellitus and obesity. The adverse events are preceded by acute worsening of oral...Full Text Available