A liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for the simultaneous determination of the 10 major components of Da-Cheng-Qi decoction (rhein, emodin, aloe-emodin, chrysophanol, rheochrysidin, naringin, naringenin, hesperidin, magnolol and honokiol) in dog plasma. Plasma samples were spiked with internal standard (ibuprofen), acidified with HCl and extracted twice by liquid-liquid extraction using ethyl acetate. Separation was performed on a YMC-Pack ODS-A C(18) column (5 microm, 150 mm x 4.6 mm) and a C(18) guard column (5 microm, 4.0 mm x 2.0 mm) with methanol-water (92:8, v/v) at a flow rate of 0.3 mL/min. The LC/MS system was operated under the multiple reaction monitoring mode using electrospray ionization in the negative ion mode. All analytes showed good linearity over a wide concentration range (r>0.99). The linear range of the calibration curves was 5000-19.53 ng/mL for rhein; ...
Among pharmaceuticals and personal care products released into the aquatic environment, antibiotics are of particular concern, because of their ubiquity and health effects. Although scientists have recently paid more attention to the threat of antibiotics to coastal ecosystems, researchers have often focused on relatively few antibiotics, because of the absence of suitable analytical methods. We have therefore developed a method for the rapid detection of 36 antibiotic residues in coastal waters, including tetracyclines (TCs), sulfanilamides (SAs), and quinolones (QLs). The method consists of solid-phase extraction (SPE) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis, using electrospray ionization (ESI) in positive mode. The SPE was performed with Oasis HLB and Oasi...
The ASFIT (Anisotropic Source-Flux Iteration Technique) code was first developed in India about 1970 to solve the radiation transport equation represented in the form of coupled integral equations separating the spatial and energy-angular transmissions. The ASFIT code uses a nodal structure in the wavelength [lambda] domain in Compton units (CU) rather than in the energy domain. The ASFIT-VARI code is the latest version available from the Radiation Shielding Information Center. It incorporates variable dimensioning and has been adapted for use on MS-DOS personal computers using the Ryan-McFarland or Microsoft Version 5.0 FORTRAN compilers. While earlier versions used point cross sections (well suited for gamma-ray transport), the present version also allows multigroup cross sections for neutron and coupled neutron-gamma-ray transport.
Fragranced consumer products are pervasive in society. Relatively little is known about the composition of these products, due to lack of prior study, complexity of formulations, and limitations and protections on ingredient disclosure in the U.S. We investigated volatile organic compounds (VOCs) emitted from 25 common fragranced consumer products-laundry products, personal care products, cleaning supplies, and air fresheners-using headspace analysis with gas chromatography/mass spectrometry (GC/MS). Our analysis found 133 different VOCs emitted from the 25 products, with an average of 17 VOCs per product. Of these 133 VOCs, 24 are classified as toxic or hazardous under U.S. federal laws, and each product emitted at least one of these compounds. For ''green'' products, emissions of these c...
Results of an investigation of the weldability of compact hollow automobile parts are reported. The use of magnetically impelled arc butt (MIAB) welding for a piston rod (OD_22_mm x 2.2_mm thickness), a shock-absorber (OD 40 mm x 2.2 mm) and a torque rod (OD 34 mm x 6 mm) has been investigated. Metallographic examination and comprehensive mechanical testing has been conducted to demonstrate the effectiveness of the method for joining of these types of automobile components
... with the symptoms of MS have MS. Diagnosis Physical examination and medical history are very important in diagnosing MS. Physical exams include a variety of tests to check ...
In this work, we explore the potential of the metalloendopeptidase Lys-N for MALDI-MS/MS proteomics applications. Initially we digested a HEK293 cellular lysate with Lys-N and, for comparison, in parallel...Full Text Available
... detected (and reported) as a by-product of MRM screening (MS/MS) targeted by Law or Rule ... detected (and reported) as a by-product of MRM screening (MS/MS) targeted by Law or Rule ...
IntroductionMale sexual dysfunction is a common complication of diabetes (DM), but the relative impact of erectile dysfunction (ED), orgasmic dysfunction (OD), and/or...Full Text Available
... POVs) overseas when space was available. ... information management system launched in 2004. ... Personally Procured Transportation (PPT) system ...
Synthetic oligoribonucleotides have been used to probe the interaction of MS2 coat protein with the translational operator of the MS2 replicase gene. We have investigated the possible formation of a...Full Text Available
ObjectiveThe aims of this study were to develop models of personality change after traumatic brain injury (TBI) based on information provided by the TBI survivor and a significant...Full Text Available
Securing the co-operation of persons supplying information required for medical statistics is essentially a problem in human relations, and an understanding of the motivations, attitudes, and behaviour...Full Text Available
AimsThis article provides a brief review of recent cross-cultural research on personality traits at both individual and culture levels, highlighting the relevance...Full Text Available
ObjectiveTo develop a simple summary risk score for the prediction of Alzheimer disease in elderly persons based on their vascular risk profiles.DesignFull Text Available
Pages 184-197: Understanding Personal Change in a Women’s Faith-Based Transitional Center/title link ...titleUnderstanding Personal Change in a Women’s Faith-Based Transitional Center/dc:title
Production costs for commercial-sized Populus plantations were developed from a series of research programs sponsored by the US Department of Energy's Short Rotation Woody Crops Program. Populus hybrid planted on good quality agricultural sites at a density of 2100 cuttings ha{sup {minus}1} was projected to yield an average of 16 Mg (OD) ha{sup {minus}1}yr{sup {minus}1}. Discounted cash flow analysis of multiple rotations showed pre-harvest production costs of $17 (US) Mg{sup {minus}1}(OD). 19 refs., 1 fig., 3 tabs.
Mechanical alloying is an important pre-requisite for the manufacturing of heat resistant oxide-dispersion-strengthened superalloys. Though the microstructure of these materials after hot extrusion and recrystallization treatment is well documented, little is known about the microstructural evolution during ball-milling. A method was tested to prepare electron transparent foils and extraction replica from powder particles for TEM investigations. The microstructure was found to consist of a Ni-Cr-Al solid solution in which submicron particles of refractory metals were embedded. The extremely fine grainize of about 50 nm is the consequence of severe plastic deformation. Yttria particles could not be detected in the powder after ball milling, but after a heat treatment at 1000 C the well-known fine dispersion of oxide particles was evident. (orig.)
This paper presents results from a research case study that examined the distribution of travel time of origin-destination (OD) pairs on a transportation network under incident conditions. Using a transportation simulation dynamic traffic assignment (DTA) model, incident on a transportation network is executed under normal conditions, incident conditions without traveler information availability, and incident conditions assuming that users had perfect knowledge of the incident conditions and could select paths to avoid the incident location. The results suggest that incidents have a different impact on different OD pairs. The results confirm that an effective traveler information system has the potential to ease the impacts of incident conditions network wide. Yet it is also important to n...
Abstract Surface modification of topography and chemistry in order to achieve a specific water contact angle (CA) has been explored by using a novel combinatorial screening platform. The screening arrays consisted of 507 distinct combinations of micro-topographies and chemical compositions. By performing chemical modifications with 1H, 1H, 2H, 2H perfluoroethyltriethoxy-silane (PFS) and n-octadecyltriethoxysilane (ODS) on standard silicon wafers it was possible to include both superhydrophobic and very hydrophilic pad arrays in the same screening platform. Surfaces modified with PFS were more hydrophobic than surfaces modified with ODS, while the unmodified silicon surfaces were hydrophilic. For the PFS modified surfaces the largest CAs were achieved with a small pillar size of X-=-1-m and...
A new eddy current array probe has been implemented as a straightforward and promising technique for detection of outer diameter (OD) surface-breaking cracks on the extrados of feeder bends. The design is based on previous work performed at AECL, which had demonstrated that eddy current probes with laterally displaced transmit-receive coils can overcome some of the limitations of inspecting ferritic steel components for surface-breaking cracks. The Feeder Integrity Joint Program-CANDU Owners Group Inc. (FIJP-COG) Non-Destructive Evaluation (NDE) Team members commissioned AECL to work in collaboration with the probe manufacturer ZETEC, to develop a field usable eddy current array probe. The objective was to acquire a technique with the following capabilities: fast scanning non-contact inspection technique for surface breaking discontinuities; full inspection of the bend extrados OD surface in a single scan; ability to inspect first and second ...
A new eddy current array probe has been implemented as a straightforward and promising technique for detection of outer diameter (OD) surface-breaking cracks on the extrados of feeder bends. The design is based on previous work performed at AECL, which had demonstrated that eddy current probes with laterally displaced transmit-receive coils can overcome some of the limitations of inspecting ferritic steel components for surface-breaking cracks. The Feeder Integrity Joint Program-CANDU Owners Group Inc. (FIJP-COG) Non-Destructive Evaluation (NDE) Team members commissioned AECL to work in collaboration with the probe manufacturer ZETEC, to develop a field usable eddy current array probe. The objective was to acquire a technique with the following capabilities: fast scanning non-contact inspection technique for surface breaking discontinuities; full inspection of the bend extrados OD surface in a single scan; ability to inspect first and second ...
The Environmental Management System (EMS) is an instrument to manage the interaction between the organization and the environment. The scope od EMS is to reduce the environmental impact and to achieve improvements in overall performances. In particular, the focus point of EMS implementation is the method for identifying and assessing significant environmental aspects. This paper presents a review of methods and techniques existing in this area, and the definition of the state of the art. The results of the literature, regulation and case studies reviews have shown that rigorous, repeatable and transparent methodologies do not exist.
There is an increased emphasis on hyphenated techniques such as immunoaffinity LC/MS/MS (IA-LC/MS/MS) or IA-LC/MRM. These techniques offer competitive advantages with respect to sensitivity and selectivity over traditional LC/MS and are complementary to ligand binding assays (LBA) or ELISA's. However, these techniques are not entirely straightforward and there are several tips and tricks to routine sample analysis. We describe here our methods and procedures for how to perform online IA-LC/MS/MS including a detailed protocol for the preparation of antibody (Ab) enrichment columns. We have included sample trapping and Ab methods. Furthermore, we highlight tips, tricks, minimal and optimal approaches. This technology has been shown to be viable for several applications, species and fluids from small molecules to proteins and biomarkers to PK assays. PMID:21872661
One of the most important aspects of security organization is to establish a framework to identify security significant points where policies and procedures are declared. The (information) security infrastructure comprises entities, processes, and technology. All are participants in handling information, which is the item that needs to be protected. Privacy and security information technology is a critical and unmet need in the management of personal information. This paper proposes concepts and technologies for management of personal information. Two different types of information can be distinguished: personal information and nonpersonal information. Personal information can be either personal identifiable information (PII), or nonidentifiable information (NII). Security, policy, and technical requirements can be based on this distinction. At the conceptual level, PII is defined ...
Morphine sulfate (MS Contin), a proven analgesic in the treatment of cancer pain and chronic benign pain, seems to be a good analgesic for the treatment of burn pain. MS Contin is morphine sulfate incorporated in a wax cellulose matrix delivery system. This wax cellulose delivery system gives MS Contin its duration of action. Ten patients were enrolled in an open-labeled, nonrandomized study. The study was designed to examine the analgesic efficacy of MS Contin in the burn population. Each patient remained in the study for 6 days. The efficacy of the analgesic regimen was subjectively measured by the visual pain scale. The MS Contin group was retrospectively compared with a group of patients who were given continuous intravenous infusions of morphine. The two groups were matched according to age, burn size, surgical procedures, and hospital stay. The analgesic qualities of ...
BackgroundLiquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is one...Full Text Available
A liquid chromatography/tandem mass spectrometric (LC/MS/MS) assay was developed for the quantitative determination of salirasib (S-trans, trans-farnesylthiosalicylic acid,...Full Text Available
This table contains point-source catalogs for the ~2 Ms exposure of the Chandra Deep ... Source positions are determined using centroid and matched-filter techniques; .... The 1-sigma upper statistical error (Gehrels 1986, ApJ, 303, ...
Personal Health Records (PHRs) are increasingly recognized as a strategy to improve patient-provider communication, availability of health information, and quality of care, by making the delivery of...Full Text Available
OBJECTIVES: Personal and equipment assistance are common strategies to reduce disability. This study sought to determine how often assistance reduces or even completely resolves health-related difficulties...Full Text Available
BackgroundPersonal health records (PHRs) provide patients with access to personal health information (PHI) and targeted education. The use of PHRs has the potential to improve a...Full Text Available
Forms used in conducting a national survey about solar energy are presented. Forms for representatives from the domestic, commercial, and industrial sectors, owners and non-owners of solar equipment, are shown. Participants were to be contacted by telephone, mail, and personal visits. (MCW)
This study identified clinical (e.g., etiology) and demographic factors related to prosthesis use in persons with upper- and lower-limb amputation (ULA and LLA, respectively) and the effect...Full Text Available
Electronic personal health records (ePHRs) can potentially maximize access and coordination of health information and improve patient/clinician collaboration, patient self-management, and health outcomes....Full Text Available
Objectives. To assess the feasibility of treating musculoskeletal pain in the lower back and/or lower extremities in persons with Parkinson's disease (PD) with cranial electrotherapy...Full Text Available
In this paper, we investigated the effect of alcohol solvents (ethanol, n-propanol, and n-butanol) and isomeric alcohol solvents (iso-propanol, iso--butanol, and tert-butanol). In addition, we observed the effect of the mixed alcohol solvents on the particle formation as using a mixture od ethanol and butanol at a ratio od 30/70, 50/50 and 70/30 vol %, respectively. In case of ethanol solvent, particle size of silica showed the smallest and the narrowest size distribution among the various solvent. On the contrary, for the n-butanol solvent, largest broad distribution of particle size was observed. For the synthesis of particles having better spherical morphology and less agglomeration, alcohol solvent having no branches was considered appropriate. When mixed alcohol solvents were used, large silica particles with narrow size distribution were obtained, regardless of the ratio. 8 refs., 5 figs., 1 tab.
PWR steam generators have suffered from a variety of degradation phenomena. This paper identifies the corrosion-related defects and their probable causes and suggests approaches to correct and prevent corrosive activity. In the attempt to solve the degradation problems, research programs have concentrated on modifying materials, stresses, and the chemical environment in both new and operating steam generators. The following corrosion-related defects have been studied: tube wastage, denting, primary side (ID) intergranular stress corrosion cracking (IGSCC), OD-initiated intergranular attack (IGA), pitting, and corrosion fatigue. Plants affected by wastage have greatly reduced their problem by adopting an all volatile treatment (AVT). In the case of denting, a less aggressive chemical environment is recommended. Primary side IGSCC responds to temperature reduction, stress relief, and material improvements, while flushing and boric acid addition minimizes ...
PWR steam generators have suffered from a variety of degradation phenomena. This paper identifies the corrosion-related defects and their probable causes and suggests approaches to correct and prevent corrosive activity. In the attempt to solve the degradation problems, research programs have concentrated on modifying materials, stresses, and the chemical environment in both new and operating steam generators. The following corrosion-related defects have been studied: tube wastage, denting, primary side (ID) intergranular stress corrosion cracking (IGSCC), OD-initiated intergranular attack (IGA), pitting, and corrosion fatigue. Plants affected by wastage have greatly reduced their problem by adopting an all volatile treatment (AVT). In the case of denting, a less aggressive chemical environment is recommended. Primary side IGSCC responds to temperature reduction, stress relief, and material improvements, while flushing and boric acid addition minimizes ...
A key factor that demands special attention in the pipeline construction is the cold bending process, since 30 to 40% of the pipes use this process in the field. This study aimed to evaluate the X80 cold bending operational parameters, in order make viable the use of this process in the installation of future onshore pipelines. Three 34''OD x 0,750'' pipes were bended. The bending was conducted using a hydraulic equipment with application of equally spaced punches, recording the correspondent angles related to the elastic and plastic deformations in order to assess the spring-back effect and performing dimensional inspection. Samples from pipe and the weld were subjected to mechanical and metallographic tests. It was possible to obtain a 19 deg curve and 27D radius without presenting any evidence of wrinkles, out of roundness or any type of mechanical damage. After analysis, all criteria established from project specifications ...
... Tanzania, and the attack on the USS COLE. ... vis another has no bearing on the legality of the attack. If the person attacked is a combatant, the use of ...
This article reviews antisocial personality disorder, psychopathy, and violence and develops a three factor model of personality traits. Then a discussion of related personality disorders precedes the development of a categorical two factor model of impulsive versus remorseless violence. A paradigm of proactive, medical, and school based early intervention and prevention is advocated as a useful addition to the reactive detention of criminal justice. Integration of psychological tests, neuroimaging, and genomic data in early childhood and school based intervention strategies to prevent the development of conduct disorder and attenuate criminal propensity inform this approach. PMID:20422651
The ODS superalloys MA 6000 and MA 760 were investigated with regard to their behaviour under non-isothermal fatigue stress. For this purpose, strain-controlled thermomechanical and bithermal experiments with different phase relationships between strain and temperature were carried out on the one hand; on the other hand, the deformation behaviour under thermomechanical stress was modelled on the basis of isothermal cyclic creep data. The fatigue experiments show that a diamond-shaped cycle derived from the stress pattern of a turbine blade is clearly less critical than in-phase and out-of-phase cycles. The life of the diamond-shaped cycle is determined by oxidation-induced crack initiation and propagation and can be predicted easily with a suitable damage model. Important damage parameters required by the model can be obtained by the less complicated bithermal fatigue tests. Modelling of the TMF hystereses suggests that cyclic, non-isothermal deformaltion is ...
The shot peening of the outer surface of Alloy 800 is proposed by the steam generator supplier in order to increase the stress corrosion cracking resistance of the tubes. The benefits and drawbacks of such a treatment are evaluated, focusing on the main concern i.e. a possible enhanced tendency of stress corrosion cracking at the transition of the expanded tube-to-tubesheet joint. Stress corrosion tests as well as residual stresses measurements demonstrate no significant difference between peened and unpeened tubes at that location. The other concerns such as stability of the compressive stresses, increased risk of pitting or intergranular attack and pollution of the secondary circuit by fragmented beads appear the as minor concerns.
The study examines the isothermal fatigue properties of novel ODS iron-base or nickel-base superalloys at temperatures of 850 C and 1050 C. The materials are different in grain structure and texture, so that particularly the effects of grain structures and textures can be studied. In order to also perform examinations of creep-fatigue interactions, various load cycles are applied. It is shown that the LCF-affected life of the grain structures of both alloy types is determined by the elastic modulus. The cyclic lifetimes determined by the conventional Manson-Coffin method for both alloy types exhibit differences of up to two orders of magnitude. Using the product of the total strain range and the elastic modulus, however, will yield precise life predictions. Under conditions of LCF stress only, the grain structure has no effect on the materials` service life, other than in the case of creep-fatigue, but the grain structure has a decisive influence on the damage ...
The fabrication of the ZT-40 torus, a large complex all-ceramic toroidal plasma containment vessel, is described. Several glass sealants covering the temperature range of 500 to 1300"0C, were developed and used to ''braze'' segments of the torus together, sapphire windows to the torus and the required pump-out and diagnostic parts to the ceramic vacuum vessel. Designs of window seals were developed that allowed sealing of the sapphire windows in a vertical position with minimum sealing glass flow.
We demonstrated direct assimilation of cellooligosaccharide using Escherichia coli displaying beta-glucosidase (BGL). BGL from Thermobifida fusca YX (Tfu0937) was displayed on the E. coli cell surface using a novel anchor protein named Blc. This strain was grown successfully on 0.2% cellobiose, and the optical density at 600 nm (OD(600)) was 1.05 after 20 h. PMID:21742905
Discusses alternative futures for distributing future personal computers, via data communications networks. The author scans and extrapolates some of the advances for impacting the emerging future of information utilities now sprouting up thoroughout the world. In particular he looks at the future of personal computers in the field of artificial intelligence,, for expert knowledge-based systems.
The main aim of sanitary pass-control regime is to prevent propagation of radioactive contamination outside the area of emergency-rescue works and guarantee of sanitary treatment of all persons having radioactive contamination. The paper has studied the questions of organization of sanitary pass-control regime, arrangement of sanitary treatment of the injured persons and rendering first aid in case of radioactive contamination of wounds. 5 refs.
Surface modification of topography and chemistry in order to achieve a specific water contact angle (CA) has been explored by using a novel combinatorial screening platform. The screening arrays consisted of 507 distinct combinations of micro-topographies and chemical compositions. By performing chemical modifications with 1H, 1H, 2H, 2H perfluoroethyltriethoxy-silane (PFS) and n-octadecyltriethoxysilane (ODS) on standard silicon wafers it was possible to include both superhydrophobic and very hydrophilic pad arrays in the same screening platform. Surfaces modified with PFS were more hydrophobic than surfaces modified with ODS, while the unmodified silicon surfaces were hydrophilic. For the PFS modified surfaces the largest CAs were achieved with a small pillar size of X = 1 {mu}m and an intermediate inter-pillar gap size of Y = 4 {mu}m with superhydrophobic CAs over 170 . Surface analysis with X-ray photoelectron spectroscopy (XPS) revealed ...
Soluble starch?based biodegradable and microporous microspheres (SDM-Ms) were prepared by emulsion chemical cross-linking technique using trisodium trimetaphosphate (TSTP) as the cross-linker. The resultant amorphous SDM-Ms were excellently identified by scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). The internal rupture and surface-controlled erosion were the predominant degradation mechanisms for SDM-Ms. The obtained SDM-Ms were applied to adsorb coix seed oil (CSO) by immersing method. The adsorption capacity of CSO within SDM-Ms was determined, namely 0.5238?g/g, and the thermal stability was shown higher than that of the free CSO. A burst release appeared in the second hour, followed by controlled release. Diffusion, d...
Abstract Previous research has established the comorbidity of adult Attention-Deficit Hyperactivity Disorder (ADHD) with different personality disorders including Borderline Personality Disorder (BPD). The association between adult ADHD and BPD has primarily been investigated at the phenotypic level and not yet at the genetic level. The present study investigates the genetic and environmental contributions to the association between borderline personality traits (BPT) and ADHD symptoms in a sample of 7,233 twins and siblings (aged 18-90 years) registered with the Netherlands Twin Register and the East Flanders Prospective Twin Survey (EFPTS) . Participants completed the Conners' Adult ADHD Rating Scales (CAARS-S:SV) and the Personality Assessment Inventory-Borderline Features Scale (PAI-BO...
In this article, we describe the development and preliminary psychometric properties of the Structured Interview of Personality Organization (STIPO), a semistructured interview designed for the dimensional assessment of identity, primitive defenses, and reality testing, the three primary content domains in the model of personality health and disorder elaborated by Kernberg (1984; Kernberg & Caligor, 2005). Results of this investigation, conducted in a clinical sample representing a broad range of personality pathology, indicate that identity and primitive defenses as operationalized in the STIPO are internally consistent and that interrater reliability for all 3 content domains is adequate. Validity findings suggest that the assessment of one's sense of self and significant others (Identity) is predictive of measures of positive and negative affect, whereas the maladaptive ways in which the subject uses his or her ...
We consider propagation of relativistic heavy nuclei injected by a young pulsar into the radiation field of a massive companion. If the binary system (BS) is compact enough, then the nuclei suffer multiple photodisintegrations in collisions with thermal photons coming from the massive star (MS). Due to the propagation effects of charged particles in the magnetic field of the MS some hadrons can impinge onto the MS surface at large angles. We calculate the fluxes of produced neutrinos as a function of the viewing angle measured from the plane of the BS. It is found that significant fluxes of neutrinos should be also expected in the case of non-eclipsing BSs.
Dogs challenged with toxic doses of methylsalicylate developed acute myocardiopathy. Metabolic manifestations of uncoupling of oxidative phosphorylation by methylsalicylate (MS) were observed. Oxygen...Full Text Available
To investigate the origin and nature of inertia, we introduce a new concept of hypothetical 2D, so-called, "master-space" (MS), subject to certain rules. The MS, embedded in the background 4D-spacetime, is an indispensable individual companion to the particle of interest, without relation to every other particle. We argue that a deformation/(distortion of local internal properties) of MS is the origin of inertia. With this perspective in sight, we construct the alternative relativistic theory of inertia (RTI), which allows to compute the relativistic inertial force acting on an arbitrary point-like observer due to its "absolute acceleration". We go beyond the hypothesis of locality with an emphasis on distortion of MS, which allows to improve essentially the standard metric and other relevant geometrical structures related to the noninertial reference frame of an arbitrary accelerated observer. We ...
A qualitative method, involving supported liquid?liquid extraction (SLE) and ultra high pressure liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS?MS), was developed for the rapid tentative identification of various drugs of abuse in urine. In this study, 28 drugs and metabolites were covered by the screening procedure. Before analysis, urine samples were extracted by SLE and good extraction recoveries were obtained for most investigated compounds. The UHPLC strategy was then selected for the rapid separation of amphetamines, cocaine, opiates and related compounds in urine. Using columns packed with sub-2??m particles, analysis time was reduced down to 2?min, while maintaining acceptable performance. Finally, the detection was by tandem MS operating in the single reaction...
A red basil cell line (T2b) rich in rosmarinic acid (RA) was selected for the stable production of anthocyanins (ACs) in the dark. Cell suspension cultures were subjected to mechanical stress through increased agitation (switch from 90 to 150rpm) to determine the relationship between AC and RA accumulation. Cell extracts were analyzed by HPLC and LC-MS, and the resulting data were processed with multivariate statistical analysis. MS and MS/MS spectra facilitated the putative annotation of several complex cyanidin-based ACs, which were esterified with coumaric acid and, in some cases, also with malonic acid. It was also possible to identify various RA-related molecules, some caffeic and coumaric acid derivatives and some flavanones. Mechanical stress increased the total AC and RA contents, ...
The Dynamic Analog Scale (DAS) is introduced as a technique for generating single-item measures of personality traits. The DAS is comprised of extensive trait definitions and an analog scale on which respondents simultaneously rate themselves and others. In two studies the Big Five personality traits were assessed with the DAS and compared to a multiple-item questionnaire that measured the same traits. Statistical analysis supported the validity of the DAS for predicting self-reported behavioral acts, drinking behaviors, affect, and religiosity in ways similar to the multiple-item questionnaire. Consistent with previous research, both studies supported the viability of measuring personality traits with single items.
Transdifferentiation of an individual's own cells into functional differentiated cells to replace an organ's lost function would be a personalized approach to therapeutics. In this two part series, we will describe the progress toward establishing functional transdifferentiated adrenal cortical cells. In this article (Part 2), we describe the disorders of the adrenal cortex, therefore establishing why there is the need for personalized cell-based therapy for individuals with these disorders. We then present our pilot studies of cell transdifferentiation toward an adrenal cortical fate using genes described in the first article of this pair (Part 1).
BackgroundProfessionalism is a critical quality for physicians to possess. Physician professionalism has received increased attention in recent years, with many authorities suggesting...Full Text Available
IntroductionThe outbreak of cholera in Zimbabwe intensified interest in the control and prevention of cholera. While there is agreement that safe water, sanitation, and personal...Full Text Available
Interest and research into the mechanisms and treatment of neuropathic pain have increased during recent years, but current treatment is still far from satisfactory (Dworkin...Full Text Available
Health Iran Iraq Landmines Middle East Muslim Outreach Narcotics Nonproliferation North Korea Pakistan Piracy Reconstruction and Stabilization Sudan Trafficking in Persons War...
... Accession Number : ADD431225. Title : Influence of Fiber Loading on Thermal Ablation of PTFE,. Corporate Author : Personal Author(s) : Letson,KN. ...
BACKGROUND.The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) covers the direct clinical costs of breast and cervical cancer screening and diagnostic follow-up for medically underserved, low-income women. Personal costs are not covered. In this report, the authors estimated personal costs per woman participating in NBCCEDP mammography screening by race/ethnicity and also estimated lifetime personal costs (ages 50-74 years).METHODS.A decision analysis model was constructed and parameterized by using empiric data from a retrospective cohort survey of mammography rescreening among women ages 50 years to 64 years who participated in the NBCCEDP. Data from 1870 women were collected from 1999 to 2000. The model simulated the flow of resources incurred by a woman participat...
Privacy-preserving machine learning algorithms are crucial for the increasingly common setting in which personal data, such as medical or financial records, are analyzed. We provide general...Full Text Available
Studies were conducted in northern Bohemia to simultaneously evaluate personal exposures to air pollution in the form of respirable particles containing polycyclic aromatic hydrocarbons (PAHs) and biomarkers...Full Text Available
... Mineral and Organic Matter in the Coastal and Near-Coastal Ocean. ... Personal Author(s) : Stavn, Robert H. ; Spiering, Bruce A. ; Gould, Richard W ...
A growing concern about the consumer behavior in Internet economy has spurred the study of Material Flow, resulting in a unique type of consumer behavioral analysis. This research proposes an enhanced conceptual model for Personalized Material Flow Services for consumer behavior. In the era of Internet information technology, customer?s taste tends to be personalized for their market demand. It is observed that there are number of ?Long Tail? phenomena in several successful e-commerce business cases. However, the Long Tail phenomenon is an open question for our research in terms of its role in e-commerce marketing. In the proposed model-X-Party Personalized Material Flow Services, three elements are discussed. They are ?providing?, ?locating? and ?obtaining? based on X-Party Material Flow ...
The authors describe the development of a four-dimensional atlas and reference system that includes both macroscopic and microscopic information on structure and function of the human brain in persons...Full Text Available
A set of computer programs is described which constitutes a clone database management system. Maintenance of the database and the stocks of material is designed to be under the control of one person...Full Text Available
The aim of this work was the examination of the coarse grain recrystallisation of the {gamma}-free ODS nickel-based alloy PM 1000 depending on the various parameters due to the processing during heat treatment. After isotropic hot compacting (HIP) of the mechanically alloyed powder, one observes a homogeneous sub-microscopic fine grain structure which can coarsen during high temperature heat treatment, due to sufficiently high driving force from the grain boundary energy via abnormal grain growth to 600 times its size. The setting of the elongated high temperature resistant recrystallisation structure is, however, not connected with this. The dependence of the sucess of re-crystallisation on the re-forming parameters (re-forming temperature and degree of re-forming) was shown by a socalled re-forming card. In order to achieve re-crystallisation to a coarse and aligned grain structure, apart from a certain absolute minimum degree of re-forming, the re-forming must ...
The Environmental Management System (EMS) is an instrument to manage the interaction between the organization and the environment. The scope od EMS is to reduce the environmental impact and to achieve improvements in overall performances. In particular, the focus point of EMS implementation is the method for identifying and assessing significant environmental aspects. The results of the literature and regulation reviews (Perotto 2006) have shown that rigourous repeatable and transparent methodologies do not exist. This paper presents a proposal method for identifying and assessing significant environmental aspects, that has all three of these important characteristics. In particular, the proposal methodology for assessing aspects is based on some criteria that are combined in a specific algorithm. It is important to specify that to make a correct application of the method a preliminary rigorous approach to investigating the environment and the activities of ...
High purity W and W-0.9La2O3 (wt.%) nanopowders were produced by a wet chemical route. The precursor was prepared by the reaction of ammonium paratungstate (APT) with lanthanum salt in aqueous solutions. High resolution electron microscopy investigations revealed that the tungstate particles were coated with oxide precipitates. The precursor powder was reduced to tungsten metal with dispersed lanthanum oxide. Powders were consolidated by spark plasma sintering (SPS) at 1300 and 1400degreeC to suppress grain growth during sintering. The final grain size relates to the SPS conditions, i.e. temperature and heating rate, regardless of the starting powder particle size. Scanning electron microscopy revealed that oxide phases were mainly accumulated at grain boundaries while the tungsten matrix ...
The Predictive Capability Maturity Model (PCMM) is a new model that can be used to assess the level of maturity of computational modeling and simulation (M&S) efforts. The development of the model is based on both the authors experience and their analysis of similar investigations in the past. The perspective taken in this report is one of judging the usefulness of a predictive capability that relies on the numerical solution to partial differential equations to better inform and improve decision making. The review of past investigations, such as the Software Engineering Institute's Capability Maturity Model Integration and the National Aeronautics and Space Administration and Department of Defense Technology Readiness Levels, indicates that a more restricted, more interpretable method is needed to assess the maturity of an M&S effort. The PCMM addresses six contributing elements to M&S: (1) ...
We review recent development in separations and mass spectrometric instrumentation for sensitive and high-throughput proteomic analyses. These efforts have been primarily focused on the development of high-efficiency (separation peak capacity of ~103) nanoscale liquid chromatography (nanoLC; e.g., flow rates extending down to ~20 nL/min at optimal separation linear velocities through narrow packed capillaries) in combination with advanced mass spectrometry (MS), including high sensitivity and high resolution Fourier transform ion cyclotron resonance (FTICR) MS. This technology enables MS analysis of low nanogram-level proteomic samples (i.e., nanoscale proteomics) with individual protein identification sensitivity at the low zeptomole-level. The resultant protein measurement dynamic range can reach 106 for nanogram-sized proteomic samples, while more abundant proteins can be detected from complex sub-picogram size proteome ...
Diethyl phthalate (DEP) and di-n-butyl phthalate (DnBP) are used extensively in personal care products, including fragrances (DEP) and nail polish (DnBP). Between May 2003 and...Full Text Available
The author recounts his experiences with insertion devices at the Stanford Synchrotron Radiation Laboratory. His first experiences with wigglers occured at the Cambridge Electron Accelerator, and was carried over to SSRL with the proposal for a six pole electromagnetic wiggler. Most modern undulators, and many wigglers are now designed around permanent magnets, and the origin of this transition at SSRL was rather fortuitous and humorous. It reflects some of the personality characteristics of Klaus Halbach.
Laboratory-based surveillance of Lyme disease in Connecticut during 1984 and 1985 identified 3,098 persons with suspected Lyme disease; 1,149 were defined as cases. Lyme disease incidence in Connecticut...Full Text Available
We present an approach to automatically generate interfaces supporting personalized interaction with digital libraries; these interfaces augment the user-DL dialog by empowering the user to (optionally) supply out-of-turn information during an interaction, flatten or restructure the dialog, and enquire about dialog options. Interfaces generated using this approach for CITIDEL are described.
In this paper a new procedure, addressed as Interpolation Damage Detecting Method (IDDM), is investigated as a possible mean for early detection and location of light damage in a structure struck by an earthquake. Damage is defined in terms of the accuracy of a spline function in interpolating the operational mode shapes (ODS) of the structure. At a certain location a decrease (statistically meaningful) of accuracy, with respect to a reference configuration, points out a localized variation of the operational shapes thus revealing the existence of damage. In this paper, the proposed method is applied to a numerical model of a multistory frame, simulating a damaged condition through a reduction of the story stiffness. Several damage scenarios have been considered and the results indicate the effectiveness of the method to assess and localize damage for the case of concentrated damage and for low to medium levels of noise in the recorded signals. The main advantage ...
Spike-timing-dependent plasticity (STDP), a form of Hebbian plasticity, is inherently stabilizing. Whether and how GABAergic inhibition influences STDP is not well understood. Using a model neuron driven by converging inputs modifiable by STDP, we determined that a sufficient level of inhibition was critical to ensure that temporal coherence (correlation among presynaptic spike times) of synaptic inputs, rather than initial strength or number of inputs within a pathway, controlled postsynaptic spike timing. Inhibition exerted this effect by preferentially reducing synaptic efficacy, the ability of inputs to evoke postsynaptic action potentials, of the less coherent inputs. In visual cortical slices, inhibition potently reduced synaptic efficacy at ages during but not before the critical period of ocular dominance (OD) plasticity. Whole-cell recordings revealed that the amplitude of unitary IPSCs from parvalbumin positive (Pv+) interneurons to pyramidal neurons ...
Measurements were carried out for calibration and performance testing of a set of 10 electronic personal dosimeters (EPDs) at the Secondary Standard Dosimetry Laboratory of Sudan. Calibrations were carried out at three X-ray beam qualities described in ISO standard 4037 in addition to 137Cs and 60Co gamma ray beams. The experimental was performed with EPDs mounted on ICRU Slab phantom. X-ray and ?-ray beams were characterized in terms of air kerma free-in-air which were converted to the known delivered personal dose equivalent, Hp(10) using appropriate the air kerma to personal dose equivalent conversion coefficients. Dosimeters tested showed excellent energy and angular response and relative error of indication within the recommended limit for photon energies from 65 keV to 1.25 MeV. The study showed encouraging results for using electronic dosimeters in personal dosimetry.
Population doses from diagnostic and therapeutic uses of radiopharmaceuticals have been estimated on the basis of a nation wide survey data on the number of investigations and treatments used radiopharmaceuticals in the nuclear medicine and the annual amount of their activities. The gonad and marrow doses were calculated from published biokinetics data from humans, employing the MIRD method. The resultant annual genetically significant dose from diagnostic and therapeutic uses of radiopharmaceuticals was 0.36 and 0.02 mrad (3.6 and 0.2 #mu#Gy) per person, respectively, with a total 0.38 mrad (3.8 #mu#Gy) per person. The annual per Caput mean bone marrow dose was 2.3 mrad (23 #mu#Gy) for diagnosis and 0.2 mrad (2 #mu#Gy), for therapy. The resultant annual leukemia significant dose was 1.8 mrad (18 #mu#Gy) per person for diagnostic uses and 0.2 mrad (2 #mu#Gy) per person for therapeutic use, with a total ...
In this paper we present a novel approach to personal photo album management allowing the end user to efficiently access the collection without any need for tedious manual annotation or indexing of the photos. The proposed work exploits methods and technology from the field of computer vision and pattern recognition for face detection, face representation and image annotation to automatically create description of images useful for content-based searching and retrieval. In fact, even if most of the used techniques are not reliable enough to address the general problem of content-based image retrieval, we show that, in a limited domain such as the one of personal photo album, it is possible to obtain results that improve the browsing capabilities of current photo album management systems. In particular, starting from the observation that most personal photos depict a usually small number of people in a relatively small ...
Joensen P. Multiple sclerosis incidence in the Faroe Islands 1986-2007. Acta Neurol Scand: 2010: 121: 348-353.Copyright 2009 The Author Journal compilation Copyright 2009 Blackwell Munksgaard. Objective - Epidemiological studies of the isolated Faroese population in 1945 identified a high annual incidence of multiple sclerosis (MS) of 10/100,000. At the time, there was speculation that the disease was brought to the country by British occupation forces resident in the islands from 1940 to 1945. The objective of the current study is to determine the incidence of diagnosis of MS in the Faroe Islands during the period 1986-2007. Methods - All patients in the Faroe Islands diagnosed with MS from July 1, 1986 to July 1, 2007 are documented in the current longitudinal, prospective study. The dia...
Discovery of better biomarkers for diagnosis, prognosis, and therapy-response prediction is the most critical task of a scientific quest aimed at developing newly designed, tailor-made therapies for patients with cancer. Consequently, a proteome wide analysis, in addition to genomic studies, is an absolute requirement for a complete functional understanding of tumor biology. Ultra-sensitive, high-performance Fourier transform ion cyclotron resonance (FTICR) mass spectrometry (MS) currently holds an important role in fulfilling the demands of biomarker discovery. In this review, we describe the applicability of FTICR MS for breast cancer proteomics, particularly for the analysis of complex protein mixtures obtained from a limited number of cells typically available from clinical specimens.
Breath analysis could offer a non-invasive means of intravenous drug monitoring if robust correlations between drug concentrations in breath and blood can be established. In this study, propofol blood and breath concentrations were determined in an animal model under varying physiological conditions. Propofol concentrations in breath were determined by means of two independently calibrated analytical methods: continuous, real-time proton transfer reaction mass spectrometry (PTR-MS) and discontinuous solid-phase micro-extraction coupled with gas chromatography mass spectrometry (SPME-GC-MS). Blood concentrations were determined by means of SPME-GC-MS. Effects of changes in pulmonary blood flow resulting in a decreased cardiac output (CO) and effects of dobutamine administration resulting in...
Guar seed gum, consisting primarily of a high molecular weight galactomannan, is the most cost effective natural thickener, having broad applications in the food, cosmetics, paper, pharmaceutical and petroleum industries. The properties of the polymer can potentially be enhanced by genetic modification. Development of suitable endosperm-specific promoters for use in guar is desirable for metabolic engineering of the seed gum. A ~1.6?kb guar mannan synthase (MS) promoter region has been isolated. The MS promoter sequence was fused with the GUS reporter gene and overexpressed in the heterologous species alfalfa (Medicago sativa). The potential strength and specificity of the MS promoter was compared with those of the constitutive 35S promoter and the seed specific ?-phaseolin promoter. Quant...
Given the concern over the potential for health risks associated with certain ingredients (e.g., phthalates) in personal care products, usage patterns of 30 types of personal care products (e.g., shampoo, sunscreen, fragrance, etc.) were collected in 604 California households through a telephone interview. Preferences in selecting products, e.g., scented or unscented, aerosol, and brand loyalty, were also investigated. Participants were recruited in three age groups, children (mostly preschoolers), their parents, and adults age 55 or older. Use frequencies of various product types varied by sex, age group, race, education, and climatic region. Product use by parent and child from the same household were correlated. Use frequencies of products in the same class (e.g., skincare) were moderat...
Collaborative Filtering (CF) is a popular method for personalizing product recommendations for e-Commerce and customer relationship management (CRM). CF utilizes the explicit or implicit product evaluation ratings of customers to develop personalized recommendations. However, there has been no in-depth investigation of the parameters of CF in relation to the number of ratings on the part of an individual customer and the total number of ratings for an item. We empirically investigated the relationships between these two parameters and CF performance, using two publicly available data sets, EachMovie and MovieLens. We conducted three experiments. The first two investigated the relationship between a particular customer?s number of ratings and CF recommendation performance. The third experim...
Personal health information management (PHIM) refers to activities that support consumers' access, integration, organization, and use of their personal health information. We investigated PHIM in the health consumer population using a focus group and participatory design. In collaboration with health consumers, we identified PHIM activities and explored the design of new supportive technology. Our findings describe prominent PHIM activities such as monitoring and assessing health, as well as health-related decision making, planning, and action. We describe design principles our participants used during the participatory design of a PHIM tool. These include individual control, sharing, integration, security and flexibility. These findings provide new insights into emerging ideas in consumer health informatics research and technology design. Understanding health consumers' PHIM needs is an important step in creating technology to support these ...
In most current recommender systems, the goal to accurately predict what people want leads to the tendency to recommend popular items, which is less helpful in revealing user?s personality, especially to new users. In this paper, we propose a heuristic music recommendation method for niche market by focusing on how to identify user?s personality as soon as possible. Instead of trying to improve algorithm's performance on new users by recommending the most popular items, we work on how to make them ?familiar? with the system earlier. The method is more suitable for brand-new users, and gives a hint to solve the cold start problem. In real applications it is better to combine it with a traditional approach.
Reliable exposure information for cosmetic and other personal care products and ingredients is needed in order to conduct safety assessments. Essential information includes both the amount of product applied, and the frequency of use. To obtain current data, studies to assess consumer use practices were undertaken. Six widely used personal care product types were included in the studies. Five of the products were cosmetics (spray perfume, hairspray, liquid foundation, shampoo, body wash) and one product was a cosmetic/over-the-counter drug product (solid antiperspirant). Three hundred and sixty women, ages 19-65 years, who regularly use the products of interest, were recruited at 10 different geographical locations within the US. The number of recruits was chosen to ensure a minimum of thr...
Brain CT images were reviewed of 98 schizophrenic patients and 90 healthy persons in relation to handedness and aging. CT images were further reconstructed to examine morphologically subtle changes in each region. Schizophrenic patients had progressive brain atrophy and dilated lateral ventricles, especially on the left side and in the posterior part of the lateral ventricle. These findings were more marked in left-handed than in right-handed schizophrenic patients. According to age groups, there were significant differences between schizophrenic and normal persons over the age of 40. The incidence of left handedness was significantly higher in schizophrenic patients in their fourties than the age-matched normal persons (31.4% vs 15.1%). Morphological abnormality and laterality might be due to the same pathologic consequences. (N.K.).
One membrane oxygen enricher (Oxygen Enrichment Company OE-4E) and four molecular sieve (MS) concentrators (Mountain Medical Econo2, De Vilbiss MINI DeVO2, Cryogenic Roomate III, and Mountain Medical...Full Text Available
... 46 DOUGLAS BOCCUZZI, MS, DABR: There are some electromagnetic fields in the room, not strong. You can ... 5 weeks or is she feeling any side effects? 00:43:33 SUSAN Y. KIM, MD: She ...
A fast and sensitive LC-ESI-MS method is described for the comparative quantification of 16 estrogen metabolites based on the derivatization of estrogens with a novel derivatizing reagent, N-methyl-nicotinic...Full Text Available
... Oliver, j. Egekeze, m. 7. Kennedy, JW Jorgenson, J. F. Parcher and ... 9. .:. W. Thackeray, HS White and MS Wrighton, J. Phys ... Dr. Harold H. Singerman ...
Various MLM-type (M, medium-chain fatty acids; L, long-chain fatty acids) structured triacylglycerols were produced in pilot- or small-scale packed-bed reactors by lipase-catalyzed acidolysis. The incorporation and acyl migration of octanoic acid were measured by gas chromatography and Grignard degradation, and ranged from 39.0 to 48.7% and 0.6 to 9.3%, respectively. Quantitation of triacylglycerol molecular species was performed by ammonia negative ion chemical ionization (NICI) mass spectrometry (MS). The proportion of ACN (acyl carbon number) 34 species that contained one C-18 fatty acid and two C-8:0, in samples analyzed, varied from 12.5 to 23.2%. The selected regioisomers MLM and MML within the ACN 34 species group were quantified by NICI tandem MS (MS/MS) and were in the range of 97.1 to 98.4% and 1.6 to 2.9%, respectively. There was no correlation between the level of acyl migration during lipase-catalyzed ...
We report the first quantitative assessment of electrosprayed droplet/ion focusing enabled by the use of a voltage-assisted air amplifier between an electrospray ionization emitter and a hybrid...Full Text Available
This study was conducted to determine by gas chromatography (GC) and mass spectrometry (MS) the identity and the quantity of volatile N products produced during the helium-purged in vivo...Full Text Available
Study objectives:To verify the existence of a symptomatic form of restless legs syndrome (RLS) secondary to multiple sclerosis (MS) and to identify possible associated risk factors.Design:Prospective,...Full Text Available
BACKGROUND: Each component of metabolic syndrome (MS) conveys increased cardiovascular disease risk, but as a combination they become much more powerful. Vigorous early management of the syndrome may...Full Text Available
We have developed a method for dissecting single neurons from the nematode Ascaris suum, in order to determine their peptide content by mass spectrometry (MS). In this paper,...Full Text Available
Seq 1 was 8 images spaced 2sec apart, 999 ms man exp, filter 0. ... This region is the 2 sigma ellipsoid. This means, there was 90% chance that ... At this point the ellipse was fat and collapsed as we were still looking more or less ...
In the IEEE Marine Technology Society OCEANS 2009 Conference, Biloxi. October 26-29, 2009. Biloxi, MS. Al-Hamdan, M.; Estes, M.; Quattrochi, D.; Thom, R.; ...
We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction...Full Text Available
Selecting an appropriate matrix solution is one of the most effective means of increasing the ionization efficiency of phosphopeptides in matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS). In this study, we systematically assessed matrix combinations of 2, 6-dihydroxyacetophenone (DHAP) and diammonium hydrogen citrate (DAHC), and demonstrated that the low ratio DHAP/DAHC matrix was more effective in enhancing the ionization of phosphopeptides. Low femtomole level of phosphopeptides from the tryptic digests of ?-casein and ?-casein was readily detected by MALDI-TOF-MS in both positive and negative ion mode without desalination or phosphopeptide enrichment. Compared with the DHB/PA matrix, the optimized DHAP/DAHC matrix yielded superior sample homogeneity and higher phosphopeptide measurement sensitivity, particularly when multiple phosphorylated peptides were assessed. Finally, the DHAP/DAHC matrix was ...
Aquaspirillum magnetotacticum MS-1 grew microaerobically but not anaerobically with NO3− or NH4+ as the sole nitrogen source. Nevertheless,...Full Text Available
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MS) has been explored widely for DNA sequencing. The major requirement for this method is that the DNA sequencing fragments...Full Text Available
A new method for the determination of {sup 237}Np and Pu isotopes in large soil samples has been developed that provides enhanced uranium removal to facilitate assay by inductively coupled plasma mass spectrometry (ICP-MS). This method allows rapid preconcentration and separation of plutonium and neptunium in large soil samples for the measurement of {sup 237}Np and Pu isotopes by ICP-MS. {sup 238}U can interfere with {sup 239}Pu measurement by ICP-MS as {sup 238}UH{sup +} mass overlap and {sup 237}Np via {sup 238}U peak tailing. The method provides enhanced removal of uranium by separating Pu and Np initially on TEVA Resin, then transferring Pu to DGA resin for additional purification. The decontamination factor for removal of uranium from plutonium for this method is greater than 1 x 10{sup 6}. Alpha spectrometry can also be applied so that the shorter-lived {sup 238}Pu isotope can be measured successfully. {sup 239}Pu, ...
BackgroundThere is need for a cognitive test battery that can be easily used in clinical practice to detect or monitor cognitive performance in patients with multiple sclerosis (MS)....Full Text Available
BackgroundMultiple sclerosis (MS) is the endpoint of a complex and still poorly understood process which results in inflammation, demyelination and axonal and neuronal degeneration....Full Text Available
... Science: London, 1987; p. 237; (b) Ratner, MA; Shriver, D. F. Chem. ... 11. Lofton, EP; Thackeray, JW; Wrighton, MS J. ... (1) Dr. Harold H. Singerman (1) ...
In multiple sclerosis (MS), oligodendrocyte and myelin destruction lead to demyelination with subsequent axonal loss. Experimental demyelination in rodents has highlighted the activation of the subventricular...Full Text Available
Objectives:There is no study about correlation between vitamin D serum level and multiple sclerosis (MS) in Iran. So in this survey, we investigated the serum level of 25-hydroxy...Full Text Available
Mitsubishi is now developing a new Pressurized water reactor (PWR), the Mitsubishi simplified PWR (MS-PWR), which has the innovative features of hybrid safety systems (an optimum combination of passive and active systems) and cooling by horizontal steam generators. In order to confirm the feasibility of the Mitsubishi hybrid safety system, various kinds of safety analyses are performed for loss-of-coolant accident events. In parallel to these safety analysis efforts, the following thermal-hydraulic tests are to be performed: (1) thermal-hydraulic test of a horizontal steam generator; (2) integrated thermal-hydraulic test using a simulation loop for the innovative MS-PWR (SLIM).
The introduction prior to series of papers on the application of neutrons for materials science (MS) in this issue starts with a brief summary of neutron scattering research history in Japan; from the individual activity by Motoharu Kimura at RIKEN early around 1940s to those at present era of world leading neutron science facilities of both JRR3 research reactor and JPARC of the largest proton Accelerator complex in Tokai. Then physical properties of low energy neutrons applied to MS as well as such neutron sources are also reviewed (http://www.jstage.jst.go.jp/browse/jvsj2). (author)
GC-MS analysis of isolated alkaloids from aerial parts of Leptadenia pyrotechnica (Forsk.) Decne (Asclepiadaceae) was performed. Twenty-four alkaloids and six simple amines were detected for the first time in this plant. Almost all of the alkaloids belonged to pyridine, pyrrole, pyrazine, and indole types. The acute LC50 of the total alkaloids and alcohol extracts estimated by means of brine shrimp toxicity test were 63.09 and 11.89 ppm, respectively. The antitumor activities of these extracts, using potato disc screen, showed good activity represented by -33.6% and -49.3%, respectively.
Isotopic analyses of radioactive materials such as irradiated nuclear fuel are of major importance for the optimization of the nuclear fuel cycle and for safeguard aspects. Among the mass-spectrometric techniques available, inductively coupled plasma mass spectrometry (ICP-MS) and thermal ionization mass spectrometry are the most frequently applied methods for nuclear applications. Because of the low detection limits, the ability to analyze the isotopic composition of the elements and the applicability of the techniques for measuring stable as well as radioactive nuclides with similar sensitivity, both mass-spectrometric techniques are an excellent amendment to classical radioactivity counting methods. The paper describes selected applications of multicollector ICP-MS in combination with c...
What has been accomplished does not die, but too often, alas, the personality of those who have handed the torch from one generation to another soon fades into oblivion.—...Full Text Available
The CPHR individual monitoring service acquired an automatic RADOS TLD system to improve its capacities to satisfy the increasing needs of their national customers. The TLD system consists of: two automatic TLD reader, model DOSACUS, a TLD irradiator and personal dosimeters card including slide and holders. The dosimeters were composed by this personal dosimeters card and LiF:Mg,Cu,P (model GR-200) detectors. These readers provide to detectors a constant temperature readout cycle using hot nitrogen gas. In order to evaluate the performance characteristics of the system, different performance tests recommended by the IEC 1066 standard were carried out. Important dosimetric characteristics evaluated were batch homogeneity, reproducibility, detection threshold, energy dependence, residual signal and fading. The results of the tests showed good performance characteristics of the system. (Author)
AbstractThis cohort study of 1302 persons aged ≥65 years, conducted in the Yoruba-speaking regions of Nigeria, determines the prevalence and correlates of hearing impairment (HI)...Full Text Available
The realization that there existed a G-protein coupled signal transduction mechanism developed gradually and was initially the result of an ill fated quest for uncovering the mechanism of action...Full Text Available
Two hundred and fifty Fellows of the American Dental Society of Anesthesiology were surveyed concerning their personal preference of anesthetic technique, regional versus general anesthesia, through...Full Text Available
The blood beryllium lymphocyte proliferation test (BeLPT) is a modification of the standard lymphocyte proliferation test that is used to identify persons who may have chronic beryllium disease. A major...Full Text Available
Sex differences in pain are frequently reported in the literature. However, less is known about possible sex differences in the experience of pain secondary to a disability. The current study...Full Text Available
Adhesive tape is often used to help athletes recover from ligament sprains of the ankle or to prevent further injury. The choice of taping technique or material is often decided by personal preference,...Full Text Available
While making economic choices, individuals assign subjective values to the available options. Values computed in different behavioral conditions, however, can vary substantially. The same person...Full Text Available
In terms of managing thrombotic disorders, genotype-based individualized patient care emerged as early as 1994 when the association of factor V Leiden (G1691A), and later, prothrombin (G20210A),...Full Text Available
The epigenome consists of non–sequence-based modifications, such as DNA methylation, that are heritable during cell division and that may affect normal phenotypes and predisposition...Full Text Available
ObjectiveTo measure self-reported physical and mental functioning and associated clinical features at study entry in 3 ethnic groups with systemic sclerosis (SSc).Full Text Available
BACKGROUND:Reports indicate that characteristics of older adults with chronic pain may be different than those of younger persons.OBJECTIVE:To study...Full Text Available
This is an informal personal review of the development over time of my ideas about the concentrating mechanism of the mammalian renal papilla. It had been observed that animals with a need to produce...Full Text Available
Several studies have raised the possibility that exposure to electrical and/or magnetic fields may be injurious to health in particular by the promotion or initiation of cancer. To investigate whether...Full Text Available
This article consists of a series of manufacturer's descriptions outlining specifications of underground monitoring equipment which range in complexity from gas sensitive personal badges to full mine monitoring systems. 8 figs.
Over the last three to four decades, it has been observed that the average total hours of sleep have decreased to less than seven hours per person per night. Concomitantly, global figures relating to...Full Text Available
A brief profile of Janet Doe is given. Twenty-five years of library automation are reviewed from the author's point of view. Major projects such as the SUNY Biomedical Communication Network and the...Full Text Available
Patent medicine vendors (PMVs) are a ubiquitous feature of the informal health sector in Nigeria. A previous study on healthcare-seeking behaviour of persons with chronic cough in southern Nigeria found...Full Text Available
'The use of personal protective clothing that covers the head is a common practice in many industries. Such personal protective clothing will impact the sound pressure level and the frequency content of sounds to which the wearer will be exposed. The use of such clothing, then, may impact speech and alarm audibility. A measure of the impact of such clothing is its insertion loss. Insertion loss measurements were performed on four types of personal protective clothing in use by Westinghouse Savannah River Company personnel which utilize cloth and plastic hood configurations to protect the head. All clothing configurations tested at least partially cover the ears. The measurements revealed that insertion loss of the items tested was notable at frequencies above 1000 Hz only and was a function of material stiffness and acoustic flanking paths to the ear. Further, an estimate of the clothing''s noise ...
While levels of weight bias vary among individuals, it is not clear why one person possesses stronger anti-fat attitudes than another person. This investigation examined whether individual differences commonly associated with greater anti-fat bias are also associated with a greater preference for thinness among people of varying levels of weight. Young adults (62% women; 84% Caucasian) recruited from psychology classes (N=308) rated four male and female figures with approximate BMIs of 18.5, 25, 30, and 40, on measures of dislike and personality characteristics and completed measures assessing weight controllability, attitudes toward the obese, and perceptual reliance. Greater negative attitudes, weight controllability beliefs, and perceptual reliance were positively associated with greater dislike and negative personality attributes among obese/severely obese figures, but inversely related among low ...
BackgroundDepressive mood is associated with mortality. Because personality has been found to be associated with depression and mortality as well, we aimed to test...Full Text Available
... different personal wellness goals for you. HIV Health Management With a good medical team and a desire to reach wellness goals , people with HIV can have a virtually normal lifespan. Take the HIV Wellness Quiz Test your knowledge and find out where you need to learn ...
Experience has shown that a list of tips provides designers and engineers with an effective guide in their areas of duties and concern. This list contains new and rare information on heat exchangers and heat recovery systems. The information presented can be used effectively with personal computers and pocket calculators and also conveniently translated into computer programs and nomographs.
Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young non-vaccinated persons have renewed interest in this zoonotic disease. Usually causing...Full Text Available
PsychoPy is a software library written in Python, using OpenGL to generate very precise visual stimuli on standard personal computers. It is designed to allow the construction of as wide a variety of...Full Text Available
We used the idea of hierarchical control to study multi-muscle synergies during a whole-body sway task performed by a standing person. Within this view, at the lower level of the hierarchy,...Full Text Available
This article offers a first-person account of a trip in Ford`s Ecostar electric minivan from Los Angeles to Sacramento. Included is an explanation of how electric vehicles work, why they are expensive to produce, which companies are pushing this new technology, battery technology, and marketing of electric vehicles.
The risks to human health from small doses of ionizing radiation raise questions which remain largely unanswered. This paper begins by explaining the historical background to this subject; it goes on to discuss recent developments and concludes with a personal view of the dose-reponse relationship. (author).
The risks to human health from small doses of ionizing radiation raise questions which remain largely unanswered. This paper begins by explaining the historical background to this subject; it goes on to discuss recent developments and concludes with a personal view of the dose-reponse relationship. (author).
...October 2006 - present: University of Leeds, UK PhD Candidate in Geochemistry Thesis Title: Magnetite formation in reducing natural environments Supervisors: Dr Liane G. Benning ...Germany Bachelor of Science in Geosciences and Astrophysics Project Details Project Title: \\
The personal neutron dosimetry becomes more important with the increasing use of nuclear and accelerator facilities. The solid state track detector, film badge and thermo-luminescent dosimeter have widely been used as passive-type personal neutron dosimeters, but the real-time neutron dosimeter is strongly needed. A real time personal dosimeter which could give neutron dose equivalent over wide energy range from thermal to 10 odd MeV by using two neutron sensors has been developed by our group. For practical commercial product, some changes from these prototype sensors have recently been done by Fuji Electric Co. Ltd. The purpose of this work is the final performance test of the dosimeter just before sale. We checked again about the sensitivity in the monoenergetic neutron field from 8 keV to 15 MeV and in the neutron fields around a few accelerator facilities. (author)
ObjectivesTo study inhalation and dermal exposure to hexamethylene diisocyanate (HDI) and its oligomers as well as personal protection equipment (PPE) use during task performance...Full Text Available
BackgroundThere is a dearth of data relating UK general practice workload to personal and social markers of individual patients.AimTo test whether there is a significant association...Full Text Available
"Correctional Health Care: Implications for Public Health Policy" is the first in a series of articles that examines the special health care needs of persons who are incarcerated in America's correctional...Full Text Available
The two haploid genome sequences that a person inherits from the two parents represent the most fundamentally useful type of genetic information for the study of heritable diseases and the development...Full Text Available
BackgroundInvestigation of the functioning of the brain in living systems has been a major effort amongst scientists and medical practitioners. Amongst the various disorder of the...Full Text Available
ObjectivePersons with chronic or recurrent pain frequently visit the emergency department (ED), yet little research examines this experience. We conducted this national survey to...Full Text Available
to Protect Workers' Rights); 2/28/07 [PDF - 1,030 KB] Submission to the docket from Eninger (private person); 3/1/07 [PDF - 174 KB] Submission to the docket from Farber (private...
Malnutrition is common among older persons, with important consequences increasing frailty and morbidity and reducing health expectancy. On the contrary, calorie restriction (CR, a low-calorie dietary...Full Text Available
Patients do considerable information work. Technologies that help patients manage health information so they can play active roles in their health-care, such as personal health records, provide...Full Text Available
Anxiety may cause adverse outcomes through physiologic pathways in patients with cardiac disease. The purpose of this dissertation was to investigate anxiety and its correlates in persons with acute myocardial infarction (AMI) and heart failure (HF). The ...
Objective:This study examined the role of cognitive factors—such as expectancies regarding the consequences of not drinking and perceptions of peer drinking—in...Full Text Available
Five methods of personality assessment are evaluated to provide guidance for the psychological treatment of patients with chronic back pain. Patient pain drawings, pentothal pain studies, stress score...Full Text Available
This study examines the longitudinal relationship between personal and sexual partner incarceration and subsequent HIV risk behaviors among drug-involved men and their primary female sexual...Full Text Available
...2010-10-01 false Who must post a geothermal bond? 3214.10 Section 3214...MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCE LEASING Personal and... § 3214.10 Who must post a geothermal bond? (a) The lessee...
...f) Are there additional requirements that must be met? (1) A person subject to this section must: (i) For fuel oils and liquid fuels, obtain, record, and keep records of the percent sulfur by weight from the vendor for each...
...persons from danger of runaway haulage equipment. (f) An audible warning...within 300 feet of preceding haulage equipment, except trailing locomotives...provided for all rubber-tired haulage equipment where such equipment is...
...competent person shall inspect haulage equipment before each shift. (ii...used. (2) Powered mobile haulage equipment shall have suitable means of... (3)(i) Power mobile haulage equipment, including trains, shall...
Acid Rock Drainage (ARD) is the product formed by the atmospheric oxidation of the relatively common pyrite and pyrrhotite. Waste rock dumps and tailings containing sulfide mineral have been reported at toxic materials producing ARD. Mining in sulphide bearing rock is one of activity which may lead to generation and release of ARD. ARD has had some major detrimental affects on mining areas. The purpose of this study was carried out to develop disposal method for preventing contamination of water and soil environment by waste rocks dump and tailings, which could discharge the acid drainage with high level of metals. Scope of this study was as following: environmental impacts by mine wastes, geochemical characteristics such as metal speciation, acid potential and paste pH of mine wastes, interpretation of occurrence of ARD underneath tailings impoundment, analysis of slope stability of tailings dam etc. The following procedures were used as part of ARD evaluation and prediction to ...
A procedure for the determination of carboxylic acids (benzoic and C{sub 8}-C{sub 16} aliphatic acids) in oxidised engine oils is described. It is based on a simple and selective derivatisation of the acids with a fluorescent label 9-anthracene-methanol followed by reverse-phase separation on an ODS column with a water-acetonitrile-tetrahydrofuran (20:40:40 by volume) mobile phase and post-column reaction with bis(2,4-dinitrophenyl) oxalate and hydrogen peroxide. The chemiluminiscence emission from the reaction was monitored using a lamina flow-through detector. Analysis of oxidised oils showed that although there was quenching of chemiluminiscence emission by the oil matrix, the acids could be determined over the range 0-0.4% (m/v) in the oil with a detection limit of 0.013% (m/v) (130 pmol on-column with a 20 {mu}l injection) for lauric acid. 8 figs., 2 tabs., 17 refs.
The use of linear accelerators in radiotherapy is of great importance in Medicine, and according to international recommendations the electron beam dosimetry has to be performed using plane-parallel ionization chambers, previously calibrated in standard gamma radiation fields at accredited laboratories. In this work, calibration methods of plane-parallel ionization chambers used in dosimetry procedures of high energy electron beams of clinical accelerators were presented, tested and intercompared. The experiments were carried out using gamma radiation beams of {sup 60} Co at the Calibration Laboratory of Clinical Dosemeters at IPEN and electron beams od 4 to 16 MeV at the Radiotherapy Department of Hospital Israelita Albert Einstein, Sao Paulo. A method was chosen to be established at IPEN. Proposals of the calibration procedure, calibration certificate and data sheets are presented. (author)
Safety studies related to the disposal of low- and intermediate waste indicate that the long term risk is determined by the presence of long-lived nuclides such as "1"4C, "5"9Ni, "6"3Ni, "9"9Tc, "1"2"9I and the transuranium elements. As most of these nuclides are difficult to measure, the correlation between these critical nuclides and some other easily measurable key nuclides such as "6"0Co and "1"3"7Cs has been investigated for typical waste streams of Paks Nuclear Power Plant (Hungary) and scaling factors have been proposed. An automated gamma-scanning monitor has been purchased and calibrated to determine the gamma-emitting radionuclides. Radiochemical methods have been developed to determine significant difficult-to-measure radionuclides. The radionuclides of interest have been "3H, "1"4C, "9"0Sr, "5"5Fe, "5"9Ni, "9"9Tc, "1"2"9I and TRUs. The measurements taken so far have revealed brand new information and data on radiological composition of waste of WWER-type reactors. The ...
One of the main factors that require special attention in a pipeline construction is the cold bending process, once depending on the region that the line will be installed the number of bends may achieve 75%, as it was observed in some areas during Campinas-Rio pipeline construction. A study was carried out to evaluate the X80 cold bending operational parameters in order to make viable the use of high strength pipes in the construction of onshore pipelines. For this analysis three pipes of 34 inches x 0.750 inches had been cold bended, the operation was carried out using a hydraulic equipment with punches applications along the pipe, recording the correspondent angles related to the elastic and plastic deformations in order to assess the material spring-back. After the bending process, samples of the weld, extrados and intrados were subjected to mechanical and metallographic tests, as well as performed dimensional inspection of the pipes. It was possible to obtain a 19 deg curve and ...
Health physicists from the Brookhaven National Laboratory (BNL) visited the Savannah River Site (SRS) as one of 12 facilities operated by the Department of Energy (DOE) contractors with annual collective dose equivalents greater than 100 person-rem (100 person-cSv). Their charter was to review, evaluate and summarize as low as reasonably achievable (ALARA) techniques, methods and practices as implemented. This presentation gives an overview of the two selected ALARA practices implemented at the SRS: Administrative Exposure Limits and Goal Setting. These dose control methods are used to assure that individual and collective occupational doses are ALARA and within regulatory limits.
Health physicists from the Brookhaven National Laboratory (BNL) visited the Savannah River Site (SRS) as one of 12 facilities operated by the Department of Energy (DOE) contractors with annual collective dose equivalents greater than 100 person-rem (100 person-cSv). Their charter was to review, evaluate and summarize as low as reasonably achievable (ALARA) techniques, methods and practices as implemented. This presentation gives an overview of the two selected ALARA practices implemented at the SRS: Administrative Exposure Limits and Goal Setting. These dose control methods are used to assure that individual and collective occupational doses are ALARA and within regulatory limits.
Transdifferentiation of an individual's own cells into functional differentiated cells to replace an organ's lost function would be a personalized approach to therapeutics. In this two part series, we will describe the progress toward establishing functional transdifferentiated adrenal cortical cells. In this article (Part 1), we describe adrenal development and function, and discuss genes involved in these processess and selected for use in our pilot studies of transdifferentiation that are presented in the second article (Part 2).
The document represents a guide for the external decontamination of persons accidentally radio contaminated due to the use, production or transport of radioactive materials. The general conditions, from the medical point of view, to be kept in mind, in the event of accidental overexposures as decontamination treatment and the handling of samples are detailed throughout report. The external contamination without injury in skin or with wound its considered. The distribution of measures and responsibilities for the therapy of the irradiated patients with radioactive materials are enumerated. The preparations of decontaminate solutions are detailed in this work. Moreover, forms for the reception, physical evaluation of the patient and external contamination are presented. (author)
Purpose - The purpose of this paper is to reflect on the stages in the development of creative activity considering the distinctive features of all stages and the modes of dynamics of the development of a creative person. Design/methodology/approach - The paper analyses scientific investigations and pedagogical experiences in order to develop the model for the formation of creative activity of artists-visual art teachers in the context of sustainable development. Findings - The investigations of scientific literature on pedagogy, psychology, philosophy, as well as the analysis of pedagogical practice allow us to recognize that the formation of creative activity is comprised of several stages. These stages are closely connected with a creative process and depend on a person's artistic talen...
During one year more than 40,000 items of information on radiation exposure of personnel involved in the handling of radiation sources and more than 5,000,000 items on irradiation of other people are collected in the authors' laboratory. Considerable progress in assessment of mean annual gonad dose of genetically sifnificant dose was attained by means of an algorithm for a personal computer. This simple and inexpensive system has led to a higher accuracy in the application of protective measures. (author).
We have developed a new type personal dosemeter by using a B-10 doped silicon p-n junction detector with a polyethylene radiator and a polyethylene moderator. The purpose of this study was to develop a real time neutron dosemeter with a nearly flat response in the energy range from thermal to 15 MeV and low angular dependence to the incident neutron direction. The neutron response of the dosemeter was obtained with the Monte Carlo calculation and the monoenergetic neutron experiment in a free air field and also under a condition attached on a phantom.
Recent rapid growth in mobile computing technologies enables telemedicine applications to operate on mobile devices. Our focus is on the design of an integrated electrocardiogram (ECG) beat detector on a Personal Digital Assistant (PDA) platform for the health screening process. The ECG beat detector module will be supported by the PDA version of Personal Health Information Management System (PHIMS) and Facilitated Accurate Referral Management System (FARMS) through wireless network infrastructure as a home-based mobile cardiac monitoring solution. PMID:17282192
A prospective study was performed on 50 patients suffering from osteochondritis dissecans of the knee and ankle to define criteria for stability and fixation of osteochondral lesions. Morphological parameters in MRI (size, fragmentation, cartilage, interface) and conventional radiology (separation, fragmentation) were registered and compared with arthroscopical staging. MRI staging based on different types of interfaces was demonstrated on T{sub 1}- and T{sub 2}-weighted images. MRI could correctly predict a Grade 1 lesion in 50%, a Grade 2 lesion in 90%, a Grade 3 lesion on 0%, and a Grade 4 lesion in 79%. Stable lesions were differentiated from unstable lesions in 90%. Radiographic findings corresponded with arthroscopic staging in only 56% of the cases because fibrotic connection may guarantee stability in case of bony separation. (orig./MG) [Deutsch] In einer prospektiven Studie an 50 Patienten mit einer Osteochondrosis dissecans (OD) des Knie- und ...
The population doses and risks of stochastic effects from occupational exposures in Japan in 1978 were estimated on the basis of a nation-wide survey. The survey was conducted on annual collective dose equivalents by sex, age group and type of radiation work for about 82,500 workers other than the workers in nuclear power stations. The data on the workers in nuclear power stations were obtained from the offitial publication of the Japan Nuclear Safety Commission. The total number of workers except for nuclear power stations was estimated to be about 170,000 persons. Radiation works were subdivided as follows: medical works including dental; nondestructive inspectional; non-atomic energy industrial; research and educational; atomic energy industrial and nuclear power industrial. The annual collective dose equivalents were estimated to be about 6,000 man rem for medical workers, 450 man rem for non-destructive inspectional, 450 man rem for non-atomic energy ...
The objective of this study was to compare contrast-enhanced magnetic resonance angiography (CE MRA) and multislice computed tomographic angiography (MS CTA) in the follow-up of thoracic stent-graft placement. The CE MRA and MS CTA were performed following nitinol stent-graft treatment due to thoracic aneurysm (n=4), intramural bleeding (n=2) and type-B aortic dissection (n=5). Corresponding evaluation of arterial-phase imaging characteristics focused on the stent-graft morphology and leakage assessment. Stent-graft and aneurysm extensions were comparable between both techniques. Complete exclusion (aneurysm, n=4; dissection, n=2) was assessed with high confidence with CE MRA and MS CTA. Incomplete exclusion (intramural bleeding, n=2; dissection, n=3) was assigned to lower confidence scores on CE MRA compared with MS CTA. On CE MRA the stent-graft lumen demonstrated an inhomogeneous signal, the stent ...
Collective dose equivalent and population dose from occupational exposures in Japan, 1988 were estimated on the basis of a nationwide survey. The survey was conducted on annual collective dose equivalents by sex, age group and type of radiation work for about 0.21 million workers except for the workers in nuclear power stations. The data on the workers in nuclear power stations were obtained from the official report of the Japan Nuclear Safety Commission. The total number of workers including nuclear power stations was estimated to be about 0.26 million. Radiation works were subdivided as follows: medical works including dental; non-atomic energy industry; research and education; atomic energy industry and nuclear power station. For the determination of effective dose equivalent and population dose, organ or tissue doses were measured with a phantom experiment. The resultant doses were compared with the doses previously calculated using a chord length technique and with data from ICRP ...
Collective dose equivalent and population dose from occupational exposures in Japan, 1988 were estimated on the basis of a nationwide survey. The survey was conducted on annual collective dose equivalents by sex, age group and type of radiation work for about 0.21 million workers except for the workers in nuclear power stations. The data on the workers in nuclear power stations were obtained from the official report of the Japan Nuclear Safety Commission. The total number of workers including nuclear power stations was estimated to be about 0.26 million. Radiation works were subdivided as follows: medical works including dental; non-atomic energy industry; research and education; atomic energy industry and nuclear power station. For the determination of effective dose equivalent and population dose, organ or tissue doses were measured with a phantom experiment. The resultant doses were compared with the doses previously calculated using a chord length technique and with data from ICRP ...
We obtained the time-lapse cumulative slip before and after the 29 November 1999, Xiuyan, Liaoning, China, Ms = 5.4 earthquake by using "repeating events" defined by waveform cross-correlation. We used the seismic waveform data from the Liaoning Regional Seismograph Network from June 1999 to December 2006. Two "multiplets" located near the seismogenic fault of the 1999 Xiuyan earthquake and the 4 February 1975, Haicheng Ms = 7.3 earthquake, respectively, were investigated. For the "multiplet" that occurred before and after the 1999 Xiuyan earthquake, apparent pre-shock accelerating-like slip behavior, clear immediate-post-seismic change, and relaxation-like post-seismic change can be observed. As a comparison, for the "multiplet" near the 1975 Haicheng earthquake which occurred a quarter century ago, the cumulative slip appears linear with a much smaller slip rate.
Mott-Schottky (M-S) analysis is an effective approach to investigate the electronic property of passive films of metals, and it is well suitable for the passive film with single space charge capacitance. But there is no proper method to analyze the C{sub sc}{sup -2} vs. V{sub m} plots of passive films with several space charge capacitances in series connection, such as bipolar passive films. In this paper, the relationship between the space charge capacitance of the bipolar passive film and the applied potential was deduced and the features of corresponding plots were given out simultaneously. Accordingly, a non-linear fitting method was presented to analyze the C{sub sc}{sup -2} vs. V{sub m} plots of bipolar passive films. Then the method was used to study the semiconductor characteristics of bipolar passive films formed on the surface of Nickel base alloy after being corroded in the environments with high temperatures and high partial pressures of H{sub ...
Mott-Schottky (M-S) analysis is an effective approach to investigate the electronic property of passive films of metals, and it is well suitable for the passive film with single space charge capacitance. But there is no proper method to analyze the Csc-2 vs. Vm plots of passive films with several space charge capacitances in series connection, such as bipolar passive films. In this paper, the relationship between the space charge capacitance of the bipolar passive film and the applied potential was deduced and the features of corresponding plots were given out simultaneously. Accordingly, a non-linear fitting method was presented to analyze the Csc-2 vs. Vm plots of bipolar passive films. Then the method was used to study the semiconductor characteristics of bipolar passive films formed on the surface of Nickel base alloy after being corroded in the environments with high temperatures and high partial pressures of H2S/CO2. The fitting results indicate that the ...
We numerically investigate whether and how gaseous ejecta from AGB stars can be converted into new stars within originally massive star clusters (MSCs) in order to understand the origin of multiple stellar populations in globular clusters (GCs). We adopt a scenario in which (i) MSCs with masses of M_s can be formed from high-mass, high-density giant molecular clouds (GMCs) in their host galactic building blocks embedded in dark matter halos at high redshifts and (ii) their evolution therefore can be significantly influenced by M_s, their initial locations, and physical properties of their hosts. Our 3D hydrodynamical simulations show that gaseous ejecta from AGB stars can be retained within MSCs and consequently converted into new stars very efficiently in the central regions of MSCs, only if M_s exceed a threshold mass (M_th) of ~10^6 M_sun. The new stars can correspond to the ``second generation (SG)'' of stars with ...
In this work we investigate the limits of uptake of metallic silver by two common metallophytes, Brassica juncea (BJ) and Medicago sativa (MS) and assess the form and distribution of the metal once sequestered by the plants. BJ accumulated up to 12.4 wt.% silver when exposed to an aqueous substrate containing 1,000 ppm AgNO{sub 3} for 72 h, however silver uptake was largely independent of exposure time and substrate silver concentration. MS accumulated up to 13.6 wt.% silver when exposed to an aqueous substrate containing 10,000 ppm AgNO{sub 3} for 24 h. In contrast to BJ there was a general trend for MS showing an increase in metal uptake with a corresponding increase in the substrate metal concentration and exposure time. In both cases the silver was stored as discrete nanoparticles, with a mean size of {approx}50 nm. According to the hyperaccumulation definition of Brooks et al. (Brooks RR, Chambers MF, Nicks LJ, ...
The multielement determination of major-to-ultratrace elements in salmon egg was carried out by ICP-AES and ICP-MS. First, salmon eggs (30 eggs used) were digested with conc. nitric acid and 60% perchloric acid by heating almost to dryness repeatedly. Finally, the residues of salmon eggs were dissolved in 1 M nitric acid and the sample solutions were analyzed by ICP-AES and ICP-MS. About 40 elements could be determined over the concentration range in 9 orders of magnitude. The concentrations of bio-essential elements, such as Zn, Fe, and Cu, in salmon egg were 10-100 times higher than those in human blood serum. In addition, the major-to-ultratrace elements in cell cytoplasm and cell membrane were separately determined in a similar manner to those in whole egg cell. The concentrations of most bio-essential elements were higher in cell cytoplasm than in cell membrane, while those of Fe and Cu were higher in cell membrane than in cell cytoplasm ...
Recently there has been much concern with the ability of plants to uptake heavy metals from their surroundings. With the development of instrumental techniques with low detection limits such as inductively coupled plasma-mass spectrometry (ICP-MS), attention is shifting toward achieving faster and more elegant ways of oxidizing the organic material inherent in environmental samples. Closed-vessel microwave dissolution was compared with conventional methods for the determination of concentrations of cerium, samarium, europium, terbium, uranium and thorium in a series of samples from the National Institute of Standards and Technology and from fields in Idaho. The ICP-MS technique exhibited detection limits in parts-per-trillion and linear calibration plots over three orders of magnitude for the elements under study. The results obtained by using nitric acid and hydrogen peroxide in a microwave digestion system for the analysis of reference ...
Intramuscular hermorrhage was induced by injecting autologous blood into the paraspinal muscle of 8 rabbits. In order to evaluate the time-dependent changes of hemorrhage observed on MRI, the animals were imaged at different stages of blood resolution at 0.02 tesla (T), and control examined with ultrasound using a 7.5 MHz linear transducer. Six inversion recovery sequences (TR=1 000 ms. TE=30 ms, and TI=18, 48, 148, 201, 302, and 398 ms) were used for the invivo calculation of T1 relaxation times. IR 1 000 (398)/30 imaging was performed before and after the Gd-DOTA administration. The hemorrhage was evident on MR images throughout the study, especially on the T2 weighted (SE 1 000/100) images. MRI showed the healing lesion longer than ultrasound. The T1 relaxation time increased during the time of resolution. Lesions on days 4 to 7 enhanced in intensity after the injection of Gd-DOTA. (orig.).
The wind speed distribution and wind energy potential are investigated in three selected locations in Oyo state using wind speed data that span between 12 and 20 years measured at 10 m height. In addition, the performance of selected small to medium size wind turbines in these sites were examined. The annual energy output and capacity factor for these turbines were determined. It was found that the monthly mean wind speeds in Oyo state ranges from 2.85 m/s to 5.20 m/s. While the monthly mean power density varies between 27.08 W/m2 and 164.48 W/m2, while the annual mean power density is in the range of 67.28 W/m2 and 106.60 W/m2. Based on annual energy output, wind turbines with cut-in wind speed of about 2.5 m/s and moderate rated wind speeds will be best suited for all the sites.
A method was developed for the determination of plutonium in the soil samples by ICP-MS with TOA extraction chromatographic column. The optimized sample loading rate is below 0.2 mL/min (column inner diameter is 3.5 mm). Using hot 0.02 mol/L oxalic acid (H_2C_2O_4) in 0.16 mol/L HNO_3 to elute Pu from the solid phase in the column. The Pu recovery of 87.3%-96.8% in soil samples was obtained. The plutonium is separated with the ion exchange method in this work. Both extraction chroma- tography and ion-exchange methods efficiently remove the uranium and matrix interference from the ICP- MS measurement. The instrumental detection limit for "2"3"9Pu was 0.48 pg/mL, which corresponds to 1, 1 mBq/mL. (authors)
National Research Institute for Materials started in FY1966 a creep data sheet project aiming at obtaining the creep test data until 360Ms (about 11 years and half) in maximum, and has continuously been conducting the above on more than 40 kinds of heat resistant metallic materials for practical use for 30 years already as of January, 1996. The 360Ms creep rupture strength which has been aimed at by this project is the basic important strength property referred to at the time of determining design allowable stress of high temperature structural members. The Institute has published the accumulation of the test data of long range creeps lasting beyond 360Ms of the Institute as a creep data sheet, and in this article, the tremendous volume of this long range creep test data is analyzed and studied systematically, the new knowledge concerning the high temperature strength properties thereby obtained is named the base creep ...
In this work, we aim to gain a better understanding of the volatility smile observed in options markets through microsimulation (MS). We adopt two types of active traders in our MS model: speculators and arbitrageurs, and call and put options on one underlying asset. Speculators make decisions based on their expectations of the asset price at the option expiration time. Arbitrageurs trade at different arbitrage opportunities such as violation of put-call parity. Difference in liquidity among options is also included. Notwithstanding its simplicity, our model can generate implied volatility (IV) curves similar to empirical observations. Our results suggest that the volatility smile is related to the competing effect of heterogeneous trading behavior and the impact of differential liquidity.
This paper describes a series of tests investigating two-phase flow regimes in a transparent model of a PWR hot leg. Test conditions were selected to cover a wide range of gas and liquid superficial velocities (.01 m/s 2 m/s) were also performed for comparison with semi-analytical predictions. Results include average void fractions, flow rates, and visual characterizations of the two-phase flow phenomena. Results show generally good agreement with Taitel and Duckler flow regime map and Zuber-Findlay correlation for average void fraction in vertical pipes. Results also indicate that flow regimes and collapsed liquid level (void fraction) are more strongly dependent on air flow rate (air superficial velocity) than water flow rate (water superficial velocity).
Abstract Aims: The aim of this study was to examine whether metabolic syndrome (MS) is associated with periodontitis in a representative sample of Korean adults, who were involved in the Fourth Korea National Health and Nutrition Examination Survey (KNHANES). Materials and Methods: A total of 7178 subjects over the age of 19 years who participated in KNHANES were examined. MS was defined as the definition proposed by the National Cholesterol Education Program Adult Treatment Panel III and the abdominal obesity cut-off line based on Korean Society for the Study of Obesity. The periodontal status was assessed by the Community Periodontal Index. Multivariate logistic regression analysis was carried out adjusting for the sociodemographics, oral health behaviours and status, and health behaviou...
The oxidation of n-butylbenzene was studied in a jet-stirred reactor (JSR) at 10atm in dilute conditions providing new experimental results over the low- and high-temperature range 550-1180K, and variable equivalence ratio (0.25ϕ1.5). They consisted of concentration profiles of the reactants, stable intermediates and final products, measured as a function of temperature, at a constant residence time of 1s, by sonic probe sampling followed by on-line GC-MS and off-line GC-TCD-FID and GC-MS analyses. The oxidation of n-butylbenzene in these conditions was modeled using a detailed chemical kinetic reaction mechanism (404 species and 2210 reactions, most of them reversible) deriving from a previous scheme proposed for the ignition, oxidation, and combustion of simple aromatics (benzene,...
Methods for the synthesis and quantitation of the novel choline analogues, telluronium choline and acetyltelluronium choline, are described. An assay procedure utilizing pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS) with cold trapping was developed with [2H4]telluronium choline and [2H4]acetyltelluronium choline as internal standards. The telluronium compounds were ion-pair extracted from tissue with dipicrylamine, washed with 2-butanone, and pyrolyzed prior to GC-MS analysis. The compounds were monitored using selected ion monitoring at m/z 232 and m/z 190 for acetyltelluronium and telluronium choline, respectively, and at m/z 236 and m/z 194 for the analogous deuterated internal standards. The assay was linear over a range of 20 pmol-20 nmol of compound taken through the assay. PMID:8130881
A simple, sensitive and rapid method for analysis of granisetron in human plasma, utilizing liquid chromatography tandem mass spectrometry (LC-MS/MS), has been developed and validated to satisfy FDA guidelines for bioanalytical methods. The analyte and internal standard (IS) were isolated from 100ml plasma samples by liquid-liquid extraction (LLE). A Varian 1200l tandem mass spectrometer equipped with an electrospray ionization source was operated in selected reaction monitoring (SRM) mode with the precursor-to-product ion transitions m/z 313.4/138 for granisetron and m/z 270/201 for the IS used for quantitation. The assay exhibited a linear dynamic range of 0.02-20ng/ml for granisetron in human plasma. The lower limit of quantification (LLOQ) was 0.02ng/ml with a relative standard deviati...
A rapid and cost-effective assessment was required to provide advice to management on the connectivity between juvenile and adult life cycle stages of Baldchin Groper Choerodon rubescens, a labrid endemic to the west coast of Australia, which has high social value, but relatively low commercial fishery importance. To minimise costs we used laser ablation ICP-MS to analyse levels of a small suite of elements (Ca, Mg, Mn, Cu, Zn, Sr, Rb, Ba and Pb) at the margin (adult phase) and core (juvenile phase) of the same otoliths of adult C. rubescens, collected at ten locations in five management zones. The elemental composition of both otolith margins and cores differed significantly among management zones and in some cases among locations within zones. Similarity of the pattern of among-zone elem...
The aim of this study was to assess the feasibility of radiosterilization of drugs aqueous solutions and to evaluate the effects of some additives, such as mannitol, nicotinamide and pyridoxine, which might protect the drug from degradation. Metoclopramide was selected as a model drug. The structures of the degradation products were determined to gain insight on the radiolysis mechanisms in aqueous solution in order to design strategies to lower the drug degradation.Metoclopramide hydrochloride aqueous solutions with and without excipients were irradiated either with gamma rays or high-energy electrons. HPLC-DAD was used to measure the loss of chemical potency and to quantify the degradation products which were also characterized by LC-APCI-MS-MS. Metoclopramide recovery for gamma and elec...
Wind speed has been measured in Patenga, Cox`s Bazar, Kuakata, Moheshkhali, and Noakhali by the computerized anemometers. The wind computers have been installed at 20 meters height. According to this study annual average wind speeds in the coastal regions of Bangladesh are greater than 6.5 m/s at the height of 20 meters. It has been observed that during day times (8 a.m. to 7 p.m.) wind speeds are about 30 to 40% higher than the average values. The value of the power exponent {alpha} has been determined in the above sites and it is 0.139. So, at 40 meters height the annual average wind speed is about 7.15 m/s. So, wind speeds in the coastal regions of Bangladesh are suitable for both water pumping and electricity generation. Details are given in this paper with graphical and analytical representations. (author)
The effect of sugar on plant metabolism, which is known to be similar to hormone-like signaling, was metabolomically studied using Melissa officinalis (lemon balm). The metabolite profiles of M. officinalis treated with sucrose were analyzed by gas chromatography-mass spectrometry (GC-MS) and principal component analysis (PCA). A total of 64 metabolites from various chemical classes including alcohols, amines, amino acids, fatty acids, inorganic acids, organic acids, phosphates, and sugars were identified by GC-MS. Three groups treated with different sucrose concentrations were clearly separated by PCA of their metabolite profiles, indicating changes in the levels of many metabolites depending on the sucrose concentration. Metabolite profiling revealed that treatment with a higher sucrose ...
Samples of vitamin D fortified orange juice obtained from retail food stores were analyzed for vitamin D3 content using a method developed by combining the best features of two AOAC methods. Detection by ultraviolet absorption at 265nm was compared to detection by selected ion monitoring (SIM) using atmospheric pressure chemical ionization (APCI) mass spectrometry (MS). Furthermore, an ion trap (IT) mass spectrometer was employed in a 'dual parallel MS' arrangement to simultaneously obtain qualitative APCI-ITMS data. The method was applied to 33 samples of 3 national American orange juice brands and 7 samples of 5 other American brands collected using a statistically designed sampling plan as part of the National Food and Nutrient Analysis Program to provide values for the USDA National Nu...
Summary The aroma impact volatiles of twenty-four pine honey samples produced in Marmaris, Data and Fethiye regions of Turkey were evaluated by solid phase micro extraction/gas chromatography/mass spectrometry (MS) technique and the results were evaluated by using the analysis of variance and Duncan tests. A total of eight common volatiles nonanal, nonanol, decanal, octanal, 16-oxosalutaridine, dodecanal, nonadecane and pentadecane were detected in three regions. The total area of the common volatiles were 73.01%, 78.10% and 73.91% in Marmaris, Data, and Fethiye regions, respectively. There were not significant differences (P-<-0.05) between the common volatiles detected in pine honey samples from three different regions. The major contributers to the pine honey aroma seems to be nonanal (...
Previous studies suggest that the radiosensitivity and origin of tissue macrophage precursors differ from those of hemopoietic macrophage colony-forming units (CFU-Ms) committed to macrophage-lineage cells. We assessed the origins of tissue macrophage colony-forming cells (M-CFCs) in mice by comparing their kinetics and radiosensitivities in the normal steady state and under the conditions of bone marrow depletion by [sup 89]Sr-administration and/or splenectomy. The results indicate that the radiosensitive peritoneal M-CFCs elicited by thioglycollate are derived from bone marrow macrophage precursors; where as alveolar M-CFCs, which are radioresistant, are self-sustained locally and independent of hemopoietic macrophage precursors. In contrast, highly radiosensitive liver M-CFCs are probably derived from CFU-Ms that appear to be propagated in the spleen in association with hemopoietic responses. (author).
An experimental and theoretical study of heat and mass transfer analogy and a comparison of that to a binary liquid mixture evaporation is presented. Common organic solvents, ethanol and n-heptane, were used to form an alcohol - hydrocarbon mixture. Studies were carried out in a horizontal rectangular channel having air flow velocities of 0.2 - 0.9 m/s. Heat transfer coefficients were measured with a copper plate resistor and mass transfer coefficients with a square pool. The heat and mass transfer analogy is presented for a system having two evaporating compounds with a fixed value of air flow and verified by measuring and comparing mass transfer coefficients for distilled water with air flow velocities of 0.2 - 0.9 m/s. An illustrative example of the use of the theory for industrial ventilation is presented. (author)
Cluster calculations of the electronic structure and charge distribution in V_3Si have been performed using two different molecular orbital methods: a semiempirical LCAO and the MS X#alpha# model. The results are compared with X-ray emission spectra and band structure calculations. An analysis of the calculated electronic distribution reveals a charge transfer from Si-atoms to V-atoms, the additional charge on a V-atom being 0.6e (LCAO) and 0.4e (MS X#alpha# method). The results are in good agreement with experiment, which indicates that the cluster approach is adequate for the description of charge distributions and spectra characteristics of the A-15 compounds. (author).
Successful electron capture dissociation (ECD) Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) applications to peptide and protein structural analysis have been enabled by constant progress in implementation of improved electron injection techniques. The rate of ECD product ion formation has been increased to match the liquid chromatography and capillary electrophoresis timescales, and ECD has been combined with infrared multiphoton dissociation in a single experimental configuration to provide simultaneous irradiation, fast switching between the two techniques, and good spatial overlap between ion, photon, and electron beams. Here we begin by describing advantages and disadvantages of the various existing electron injection techniques for ECD in FT-ICR MS. We next ...
High molecular weight products of the ozonolysis reaction of particle-phase 9-octadecenoic acid (oleic acid) have been studied by photoelectron resonance capture ionization (PERCI) mass spectrometry (MS). Oleic acid particles ( Formula Not Shown , Formula Not Shown ) were reacted with ozone (1.8x10-4atm) in a flow reactor at reaction times of 8 and 23s. Particles were sampled on-line with a differentially pumped particle inlet and chemically analyzed by PERCI-MS. PERCI is a soft ionization method that permits the direct measurement of relatively high molecular weight compounds, facilitating molecular identification. In addition to cyclic oxygenates, such as secondary ozonides and geminal diperoxides that were reported previously, we demonstrate the formation of polymers at the particle sur...
A UPS based on a line-interactive system for CATV (Cable TV) networks has been newly developed. An inverter of the UPS featuring a pure sine wave output and equipped with an uninterrupptible transfer switch made it possible to raise its reliability high and to reduce the uninterruptible transfer time from 50 {approx} 100 ms to only 3 ms. The expected life of 15 years and maintenance-free of the UPS were realized by monitoring and optimizing the operational conditions of lead-acid batteries, aluminum electrolytic capacitors and cooling fans. The use of rust- and weather- resistant painting methods for an outer box of the UPS also contributed to extend the life of the system. (author)
Phenytoin (PHT), phenobarbital (PHB), lamotrigine (LTG), and topiramate (TPM) are some of the most widely used antiepileptic drugs (AEDs). Monitoring of their concentrations in serum is important for the treatment of epilepsy. A reference measurement procedure (RMP) for certification of PHT, PHB, LTG, and TPM in serum has been developed and critically evaluated. Isotopically labeled compounds of PHT, PHB, LTG, and TPM are used as internal standards for the four AEDs. The four drugs and their respective labeled internal standards are simultaneously extracted from serum using solid-phase extraction prior to reversed-phase liquid chromatography?tandem mass spectrometry (LC-MS/MS). Chromatographic separation was performed using a C18 column. Electrospray ionization (ESI) in the positive ion mo...
The use of chemically selective laser ionization combined with {beta} -delayed neutron counting at CERN/ISOLDE has permitted identification and half-life measurements for 623-ms {sup 61}Mn up through 14-ms {sup 69}Mn . The measured half-lives are found to be significantly longer near N=40 than the values calculated with a quasiparticle random-phase-approximation shell model. Gamma-ray singles and coincidence spectroscopy has been performed for {sup 64,66}Mn decays to levels of {sup 64,66}Fe , revealing a significant drop in the energy of the first 2{sup +} state in these nuclides that suggests an unanticipated increase in collectivity near N=40 . {copyright} {ital 1999} {ital The American Physical Society }
The use of chemically selective laser ionization combined with #beta# -delayed neutron counting at CERN/ISOLDE has permitted identification and half-life measurements for 623-ms "6"1Mn up through 14-ms "6"9Mn . The measured half-lives are found to be significantly longer near N=40 than the values calculated with a quasiparticle random-phase-approximation shell model. Gamma-ray singles and coincidence spectroscopy has been performed for "6"4","6"6Mn decays to levels of "6"4","6"6Fe , revealing a significant drop in the energy of the first 2"+ state in these nuclides that suggests an unanticipated increase in collectivity near N=40 . copyright 1999 The American Physical Society.
Objective Multiple sclerosis (MS) and its animal counterpart experimental autoimmune encephalomyelitis (EAE) have a major inflammatory component that drives and orchestrates both diseases. One particular group of mediators are the prostaglandins (PGs), which we have previously shown, through quantitation and pharmacological intervention, to be closely involved in the pathology of MS and EAE. The aim of the current study was to determine the expression of the PG-generating cyclooxygenase (COX) enzymes and the profile of PGE2 and PGD2, in selected central nervous system (CNS) tissues, with the development of the chronic relapsing (CR) form of EAE. In particular, the work investigates the possible relationship between the expression of COX isoenzymes and PG levels during the neurological phas...
The aim of this study is to evaluate the specificities of the irradiation of drugs in frozen aqueous solution. The structures of the degradation products were determined to gain insight into the radiolysis mechanisms occurring in frozen aqueous solutions. Metoclopramide hydrochloride and metoprolol tartrate were chosen as models. The frozen solutions were irradiated at dry ice temperature by high energy electrons at various doses. The drug purity (chemical potency) and the radiolysis products were quantified by HPLC-DAD. Characterization of the degradation products was performed by LC-APCI-MS-MS. The structures of the radiolysis products detected in irradiated frozen aqueous solutions were compared to those detected in solid-state and aqueous solutions (previous studies). For both metoclop...
There are two types in quench distortion of steel parts: thermal distortion and transformation distortion. Quench distortion is caused mainly by uneven cooling rate of steel parts from Austenitising temperature. The rapid cooled side is lengthened (convex deformation); the slow cooled side is shortened (concave deformation). So, to control the quench distortion, it is necessary to regulate the cooling rate of steel parts during quenching. TWO COMPONENTS produce the quench distortion of steel parts: the thermal stress and transformation stress. Generally, the effect of the thermal stress on the quench distortion is stronger than the transformation stress. The quench distortion is caused by uneven cooling rate of the steel parts, from Austenitising temperature to Ms point and Ms-Mf range. So, to control the quench distortion, it is very important to regulate the cooling rate of the steel parts during quenching. The purpose of this paper is to ...
Twenty-three patients with intracranial meningiomas were examined by means of magnetic resonance tomography (MRT). In 13 patients the paramagnetic contrast medium gadolinium DTPA was used. Meningiomas show only slight changes in signal intensity compared with brain in the spin-echo mode, the greatest contrast being found on photon density images (TR 1600 ms, TE 35 ms). In T1 images more than 50% of the patients showed a low signal margin between tumour and brain. Hyperostosis of the calvarium is easily recognised, but MRT is unreliable for showing tumour calcification. After intravenous injection of gadolinium DTPA, there was marked homogeneous uptake in the meningiomas. These signs are useful for the diagnosis of a meningioma by MRT. (orig.).
The behavior of the triterpenes friedelin and friedelan-3-ol, contained on the leaves of Maytenus aquifolium Martius (Celastraceae), upon several doses of X- and #gamma#-rays (10 to 100 kGy), was investigated by high resolution gas chromatography (HRGC) and high resolution gas chromatography -mass spectrometry (HRGC-MS). The friedelin content has not changed with #gamma#-irradiation, but the content of friedelan-3-ol decreased around 17% at doses of 10, 20 and 40 kGy and around 27% at doses of 60, 80 and 100 kGy. The levels of both triterpenes remained unchanged even at higher X-ray doses. Lupen-3-one was detected by HRGC-MS. (author).
A plutonium gamma-ray analysis system that operates on MS-DOS-based computers has been developed for the International Atomic Energy Agency (IAEA) to perform in-field analysis of plutonium gamma-ray spectra for plutonium isotopics. The program titled IAEAPU consists of three separate applications: a data-transfer application for transferring spectral data from a CICERO multichannel analyzer to a binary data file, a data-analysis application to analyze plutonium gamma-ray spectra, for plutonium isotopic ratios and weight percents of total plutonium, and a data-quality assurance application to check spectral data for proper data-acquisition setup and performance. Volume 3 contains the software listings for these applications.
A recently developed hydrodistillation?solvent microextraction (HD?SME) method coupled to gas chromatography?mass spectrometry (GC?MS) was applied to the analysis of volatile components of aerial parts of Echinophora cinerea (Boiss). By the use of a simplex optimization method, the effects of extraction time, sample weight and microdrop volume on the extraction efficiency of the method were optimized. In the optimized conditions, 3??L of n-heptadecane was suspended in the headspace of 6?g of hydrodistillating sample, using a microsyringe. After 7?min, the solvent was retracted back into the syringe and directly injected into the GC?MS injection port. The HD?SME method was compared to a conventional hydrodistillation technique. In general, the extraction with HD?SME was relatively faster an...
Worker exposures to N-nitroso compounds were evaluated at B.F. Goodrich Company, Woodburn, Indiana on December 12, 1979. Personal and area air samples were collected and analyzed by gas-chromatography and thermal-energy-analysis methods. All of the samples contained N-nitrosomorpholine (NMOR) and five samples also contained N-nitrosodimethylamine (NDMA). The amount of NMOR ranged from 0.85 to 3.7 micrograms per cubic meter (micrograms/cu m) for area air samples and 0.63 to 1.8 micrograms/cu m for personal samples. NDMA concentrations ranged from undetectable to 1.8 microgram/cu m for area samples and undetectable to 0.09 micrograms/cu m for personal samples. The authors note that no exposure standards exist for NDMA or NMOR but both are listed as potential human carcinogens. They suggest that the B.F. Goodrich Company characterize nitrosamine exposures at this facility.
The minimum cardiac transit times (MTT's) at rest and following sub-maximum stresses were measured in 97 individual examinations of untrained persons and high performance athletes. It turned out that there is a strong dependence on cardiac frequency of the MTT's. This relation can be described quite satisfactorily by a hyperbolic function and in this way allows a frequency correction to be made of the MTT's. The MTT's standardized in this way (MTT.f values) represent the quotient of the end diastolic segment volume/beat volume. In the whole lesser circulatory system almost identical MTT.f values were found for the two groups under comparison at rest and following stress. In the ventricles, however, and especially so in the left ventricle, the MTT.f values were clearly higher with athletes than with untrained persons, but they strongly decreased after stresses, while the respective values remained almost constant in ordinary ...
It is possible to slow down the progression of Alzheimer's disease with pharmacological treatment. When this treatment is given to people with types of dementia that affect the frontal and temporal lobes (Frontotemporal Dementia) the results are discouraging. It is observed that the patients show pronounced restlessness and mania. In this article we describe a nonpharmacological psychosocial approach, music therapy, and how it is possible to work with this method when constitutional, regulative, dialogical, and integrative aspects are included. The focus is on therapeutic singing where well-known songs are applied in order to build up structure and stability and/or as means of arousal regulation. Songs with personal meaning make it possible to acknowledge the person's emotions, breaking the social isolation, and meeting the music therapy participant's psychosocial needs. The clinical approach is an integration of a relational music therapy ...
Personal authentication is an important process we encounter almost every day; when we are logging on a computer, entering a company where we work, or a restricted area, when we are using our plastic credit cards to pay for a service or to complete some other financial transaction, etc. In each of these processes of personal authentication some kind of magnetic or optical token is required. But by using novel technologies like mobile computing and wireless networking, it is possible to avoid carrying multitude of ID cards or remembering a number of PIN codes. Article shows how to efficiently authenticate users via Personal Area Networks (PAN) like Bluetooth or IrDA using commonplace AES (Rijndel) or MD5 encryption. This method can be implemented on many types of mobile devices like Pocket PC PDA with Windows CE (Windows Mobile 2003) real-time operating system, or any other customized OS, so we will explain all components ...
Radiation doses to workers at the Manhattan Engineer District (MED) and US Atomic Energy Commission (AEC) sites due to external irradiation during 1940--1960 are reviewed. Categorized radiation dose data were available from AEC annual reports for some years. Annual individual radiation dose data for ten MED/AEC sites for all years were available from the US Department of Energy`s (DOE) Comprehensive Epidemiologic Data Resource (CEDR). These data are combined to produce an estimate of external collective dose equivalent to 172,000 person-rems (1720 person-Sv) for 1940--1960. During this period there were 41 overexposures, 19 criticality incidents, and 3 deaths due to acute radiation syndrome among several hundred thousand workers.
Previous research demonstrates that we tend to derogate individuals who are perceived to be in a social relationship with stigmatized persons. Two experiments examined whether this phenomenon also occurs for individuals seen in the presence of an obese person and whether a social relationship is necessary for stigmatization to spread. The results from both experiments revealed that a male job applicant was rated more negatively when seen with an overweight compared to a normal weight female and that just being in the mere proximity of an overweight woman was enough to trigger stigmatization toward the male applicant. Experiment 2 examined possible moderating effects of the proximity finding. Applicants seated next to heavy (vs. average weight) individuals were denigrated consistently regardless of the perceived depth of the relationship, the participant's anti-fat attitudes or gender, and whether or not positive information was presented ...
Babcock and Wilcox Volund is a major European provider of energy producing plants based on biomass and waste materials, which was founded in 1898 and today employs about 400 persons with headquarters and manufacturing in Esbjerg, Denmark. The R and D staff is about 10 persons, concentrating on gasification and improvement of traditional products. The Company turnover is about 120 mio. Euro annually, of which about 80 % is exported (50 % outside Europe - mostly far East). In 2000 the Company was acquired by US Company Babcock and Wilcox. In 1988 Volund initiated the development of updraft wood-chips gasifier Technology, which led to the commissioning of the Harboore gasifier early 1994. The work was supported in part by the Danish ELKRAFT Power Utilities and the Danish Energy Agency. The development process was carried out until 2002 and Volund now just concluded a license agreement with the Japanese engineering Company JFE. The overall layout ...
In recent years, slightly acid formulas for cosmetics which remove follicular infundibulum obstruction of the hair follicle, have been devised. Therefore, few acne patients experience a problem with cosmetics use. On the other hand, cosmetics use differs from person to person. Thus, an investigation of actual conditions of cosmetics use was done among acne patients. Compared with healthy people, acne patients used more facial wash products more. It has been understood that treatment and skincare instruction are important for the improvement and prevention of acne. We examined skin physiology function and patient's QOL by using a skin care product for women for two months with skincare instruction from a dermatologist for 31 female patients this time. As a result, it was able to be confirme...
Sex differences in pain are frequently reported in the literature. However, less is known about possible sex differences in the experience of pain secondary to a disability. The current study explored these issues in persons with limb loss (n = 335, 72% men) who were recruited as part of a postal survey. Participants provided ratings of phantom limb pain (PLP), residual limb pain (RLP), and general pain intensity. Participants also completed measures of pain-related interference, catastrophizing, coping, and beliefs. Results indicated that a greater proportion of males than females (86% vs 77%, respectively) reported the presence of PLP; however, this difference was no longer prominent when cause of limb loss was controlled. No sex differences were found in the presence of RLP, or in avera...
... The drop in pay, with mounting medical bills and a curve ball in their personal life, led Mr. Flake and his wife, Amy, to exhaust their savings. As they shifted spending to credit cards their debt mounted, and conversations about retirement ... In October 2008, they learned that a relative of hers with an 8-month-old son was going to prison. If the Flakes could not take the baby, he would be placed in foster care. The Flakes did some soul searching and decided to seek custody of ...) 1 2 Next Page »A version of this article appeared in print on March 24, 2011, on page F4 of the New York edition. Sign In to E-Mail Print Single Page Reprints Connect with The New York Times on Facebook. Get Free E-mail Alerts on These Topics Retirement Personal ...
The radiation control carried out in Atomic Energy Research Institute, Kinki University, for the reactor installation and the tracer/accelerator facilities from April, 1981, to March, 1982, is described. The reactor was operated for total 1057.1 hours at the maximum heat output of 1 W. The persons subject to radiation protection as of April, 1981, were 126 persons in all, including 23 in radiation work and 11 in X-ray work, etc. The contents of this report are as follows: personnel monitoring (health examination, the control of individual exposure dose); laboratory monitoring (the measurement of area dose rate, radioactive concentration in air and water, and surface contamination density); field monitoring (environmental ..gamma..-ray dose rate, radioactive concentration in environmental samples); the use of unsealed radioisotopes, etc.
DOE installations possessing sufficient quantities of fissile material to potentially constitute a critical mass, such that the excessive exposure of personnel to radiation from a nuclear accident is possible, are required to provide nuclear accident dosimetry services. This document describes the personal nuclear accident dosimeter (PNAD) used by SNL and prescribes methodologies to initially screen, and to process PNAD results. In addition, this report describes PNAD dosimetry results obtained during the Nuclear Accident Dosimeter Intercomparison Study (NAD23), held during 12-16 June 1995, at Los Alamos National Laboratories. Biases for reported neutron doses ranged from -6% to +36% with an average bias of +12%.
Background: High satisfaction rates have been reported after autologous breast reconstruction. Yet, most mastectomy patients receive implant reconstructions (ImBR). Independent and active decision makers have shown mainly to choose for autologous reconstructions, such as the Deep inferior epigastric perforator (DIEP) flap (DiepBR). To further explore the decision making to opt for either ImBR or DiepBR, we investigated patient knowledge, informational resources used, effect of plastic surgeons' advice, coping style and personal independence. Methods: A total of 153 women, who were planned for DiepBR or ImBR preoperatively, completed a study-specific and standardised validated psychological questionnaire. Analyses were aimed at information-seeking behaviour, personal independence and coping...
An in/depth industrial hygiene survey of exposures to phosphine during the use of aluminum phosphide was conducted as part of a survey on exposure to grain fumigants. Area monitoring and breathing-zone sampling for phosphine were conducted during the addition of aluminum phosphide to grain during turning operations; source samples and peak personal exposures were also analyzed. Major sources of personal exposure included the escape of air from the bin headspace during filling with treated grain, filling and emptying of the phosphide pellet dispenser, and infiltration from the treated grain bin and from the pellet dispenser itself into adjacent air space. Relatively good dust control was indicated by the total dust samples collected during the survey. Measures recommended by the author are in the report.
Background In scientific literature, when the consequences of illness are discussed, one finds that the deficit perspective is prevailing: Illness as the cause for loss of abilities and a loss of contentment. On the other hand, particularly with creative people, an increase of creativity can be observed, following a confrontation with and having endured a period of illness. When one considers the occurrence of illness retrospectively in a biographical context, one may find often a biographical standstill. Although illness and disease are considered as a collapse, one may observe also psycho-spiritual maturation processes during the confrontation with illness. In several cases illness can thus result in personality maturation and a higher level of psychological health. Aims Despite of the f...
With the issuance of the Decommissioning Rule (July 27, 1988), nuclear power plant licensees are required to submit to the US Regulatory Commission (NRC) for review, decommissioning plans and cost estimates. This user`s manual and the accompanying Cost Estimating Computer Program (CECP) software provide a cost-calculating methodology to the NRC staff that will assist them in assessing the adequacy of the licensee submittals. The CECP, designed to be used on a personnel computer, provides estimates for the cost of decommissioning PWR plant stations to the point of license termination. Such cost estimates include component, piping, and equipment removal costs; packaging costs; decontamination costs; transportation costs; burial costs; and manpower costs. In addition to costs, the CECP also calculates burial volumes, person-hours, crew-hours, and exposure person-hours associated with decommissioning.
Alcohol dependence (AD) is clinically and etiologically heterogeneous. The goal of this study was to explore AD subtypes among a sample of 1221 participants in the Irish Affected Sib Pair Study of Alcohol Dependence, all of whom met DSM-IV criteria for AD. Variables used to identify the subtypes included major depressive disorder, antisocial personality disorder, illicit drug dependence (cannabis, sedatives, stimulants, cocaine, opioids, and hallucinogens), nicotine dependence, the personality traits of neuroticism and novelty seeking, and early alcohol use. Using latent class analysis, a 3-class solution was identified as the most parsimonious description of the data. Individuals in a Mild class were least likely to have comorbid psychopathology, whereas a severe class had highest probabi...
Three electronic personal dosimeters (EPD-N) manufactured by Siemens, serial numbers 0635, 0658, and 0683, were tested at the Radiation Calibration Laboratory for an evaluation of their response to neutron, gamma and x-ray radiation. Designed to provide real-time neutron and photon dosimetry, the EPD-N is capable of estimating and displaying neutron and gamma dose components separately for a range of energies from 50 keV to 7 MeV for photon and 0.025 eV to > 10 MeV for neutron. All tests were conducted using the factory calibrations. A technical representative of the manufacturer indicated that site-specific calibrations are required as factory settings are calibrated for the lowest neutron energy limit of 0.025 eV. This raises concerns about the reliability of these devices in measuring neutrons when calibrations are made for a specific site radiological characterization then used at another site.
The majority of research on homeless youth has focused on the multitude of problems faced by this vulnerable population. The current study, while acknowledging the hazards of life on the streets, seeks to explore the personal strengths and informal resources street youth rely on to navigate their environments. Qualitative data from seven focus groups conducted with street youth ages 18?24 were analyzed using content analysis. These data, rich with interactions among youth participants, highlight three important themes: developing ?street smarts,?? existence of personal strengths, and informal resources relied upon by youth to survive. Results provide valuable insights into the strengths of homeless youth that can be useful to providers in assessing street youths? service needs and increasi...
AbstractBACKGROUND: The authors chose to examine the association between body mass index (BMI) and incident colorectal cancer across the spectrum of BMI, including underweight persons, because detailed prospective cohort data on this topic in Asians is scarce, as is data on underweight persons (BMI, <18.5 kg/m2) in any population. METHODS: Analysis of the Singapore Chinese Health Study included 51,251 men and women aged 45-74 years enrolled in 1993-1998 and followed through 2007. Incident cancer cases and deaths among cohort members were identified through record linkage, and 980 cases were identified. Cox regression models were used to investigate the association of baseline BMI with risk of incident colorectal cancer during a mean of 11.5 years of follow-up. RESULTS: A significant, U-sha...
Summary Background:- Cholinesterase inhibitors form the mainstay of treatment for persons with mild-to-moderate Alzheimer-s disease (AD). The rivastigmine patch may increase compliance and the proportion of patients maintaining an efficacious dose compared with oral cholinesterase inhibitors. Objective:- To investigate the proportion of patients who reached and maintained the target rivastigmine patch dose compared with the target rivastigmine capsule dose reported in clinical trials. Methods:- This was a multicentre, 24-week, open-label study in persons with probable AD and a Mini-Mental State Examination (MMSE) score of --10 and --26. The primary outcome was the proportion of patients (ITT population) treated with 9.5-mg/24-h rivastigmine patch for at least 8-weeks at week 24. Secondary ...
A new method that allows rapid preconcentration and separation of plutonium and neptunium in water samples was developed for the measurement of "2"3"7Np and Pu isotopes by inductively-coupled plasma mass spectrometry (ICP-MS) and alpha spectrometry. "2"3"8U can interfere with "2"3"9Pu measurement by ICP-MS as "2"3"8UH"+ mass overlap and "2"3"7Np via peak tailing. The method provide enhanced removal of uranium by separating Pu and Np initially on TEVA Resin, then moving Pu to DGA resin for additional removal of uranium. The decontamination factor for uranium from Pu is almost 100,000 and the decontamination factor for U from Np is greater than 10,000. This method uses stacked extraction chromatography cartridges and vacuum box technology to facilitate rapid separations. Preconcentration is performed using a streamlined calcium phosphate precipitation method. Purified solutions are split between ICP-MS and alpha spectrometry ...
A new method that allows rapid preconcentration and separation of plutonium and neptunium in water samples was developed for the measurement of {sup 237}Np and Pu isotopes by inductively-coupled plasma mass spectrometry (ICP-MS) and alpha spectrometry; a hybrid approach. {sup 238}U can interfere with {sup 239}Pu measurement by ICP-MS as {sup 238}UH{sup +} mass overlap and {sup 237}Np via peak tailing. The method provide enhanced removal of uranium by separating Pu and Np initially on TEVA Resin, then moving Pu to DGA resin for additional removal of uranium. The decontamination factor for uranium from Pu is almost 100,000 and the decontamination factor for U from Np is greater than 10,000. This method uses stacked extraction chromatography cartridges and vacuum box technology to facilitate rapid separations. Preconcentration is performed using a streamlined calcium phosphate precipitation method. Purified solutions are split between ...
We show that the size of a lanthanide-ion doped nanoparticle can be accurately determined from its luminosity. The optically determined size distribution is in very good agreement with the distribution obtained from transmission electron microscopy. These data confirm that single nanoparticles are visualized in microscopy experiments. Nanoparticles as small as 13 nm are detectable with integration times of 500 ms.
We examined the effect of the trophic protein, nerve growth factor (NGF), on cultures of fetal rat neostriatum and basal forebrain-medial septal area (BF-MS) to define its role in brain development. Treatment of cultures with NGF resulted in an increase in the specific activity of the cholinergic enzyme choline acetyltransferase (CAT) in both brain areas. CAT was immunocytochemically localized to neurons. In the BF-MS, NGF treatment elicited a marked increase in staining intensity and an apparent increase in the number of CAT-positive neurons. Moreover, treatment of BF-MS cultures with NGF increased the activity of acetylcholinesterase, suggesting that the cholinergic neuron as a whole was affected. To begin defining mechanisms of action of NGF in the BF-MS, we detected NGF receptors by two independent methods. Receptors were localized to two different cellular populations: neuron-like cells, and ...
We have investigated the nanocrystalline microstructure and the hard magnetic properties of Sm(Co{sub 0.725}Fe{sub 0.1}Cu{sub 0.12}Zr{sub 0.04}B{sub 0.015}){sub 7.4} melt-spun ribbons. The coercivity (H{sub c}) of the as-spun ribbons increased with the wheel surface speed from 2.8kOe for 10m/s to 14.5kOe for 40m/s. The post-annealing of the melt-spun ribbons from 700 to 900 deg. C for 10min did not lead to a substantial increase of H{sub c}. However, after isothermal aging at 820 deg. C and subsequent slow cooling (0.5 deg. C/min) to 120 deg. C, H{sub c} increased from 2.8 to 10.9kOe for 10m/s, while it decreased from 14.5 to 13.5kOe for 40m/s ribbons. The grain size of the melt-spun ribbon reduced with structural transformation from 2:17H (Th{sub 2}Ni{sub 17}-hexagonal type) to 1:7H (TbCu{sub 7}-hexagonal type) as the wheel surface speed was increased. Three-dimensional atom probe analysis showed a ...
We have investigated the nanocrystalline microstructure and the hard magnetic properties of Sm(Co_0_._7_2_5Fe_0_._1Cu_0_._1_2Zr_0_._0_4B_0_._0_1_5)_7_._4 melt-spun ribbons. The coercivity (H_c) of the as-spun ribbons increased with the wheel surface speed from 2.8kOe for 10m/s to 14.5kOe for 40m/s. The post-annealing of the melt-spun ribbons from 700 to 900 deg. C for 10min did not lead to a substantial increase of H_c. However, after isothermal aging at 820 deg. C and subsequent slow cooling (0.5 deg. C/min) to 120 deg. C, H_c increased from 2.8 to 10.9kOe for 10m/s, while it decreased from 14.5 to 13.5kOe for 40m/s ribbons. The grain size of the melt-spun ribbon reduced with structural transformation from 2:17H (Th_2Ni_1_7-hexagonal type) to 1:7H (TbCu_7-hexagonal type) as the wheel surface speed was increased. Three-dimensional atom probe analysis showed a boron enriched precipitate at the grain ...
E-beam and gamma products from the radiolysis of aqueous solutions of (+-)-metoprolol tartrate, saturated in nitrogen, are analyzed by HPLC with on-line mass and UV detectors. The structures of 10 radiolytic products common to e-beam and gamma irradiations are elucidated by comparing their fragmentation pattern to that of (+-)-metoprolol. Two of the radiolytic products are also metabolites. Different routes for the formation of the radiolytic products are proposed.
Organic molecules are a significant and highly varied component of atmospheric aerosols. Measurement of aerosol composition and improvements in our understanding of the complex chemistry involved in their formation and aging are being aided by innovations in soft ionization aerosol MS. (To listen to a podcast about this feature, please go to the Analytical Chemistry multimedia page at pubs.acs.org/page/ancham/audio/index.html.). PMID:21275431
We have used intramolecular cross-linking, MS, and sequence threading to rapidly identify the fold of a model protein, bovine basic fibroblast growth factor (FGF)-2. Its tertiary structure was probed...Full Text Available
Two-phase air-water flows in a microscale fractal-like flow network were experimentally studied and results were compared to predictions from existing macroscale void fraction correlations and flow regime maps. Void fraction was assessed using (1) two-dimensional analysis of high-speed images (direct method) and (2) experimentally determined using gas velocities (indirect method). Fixed downstream-to-upstream length and width ratios of 1.4 and 0.71, respectively, characterize the five-level flow network. Channels were fabricated in a 38 mm diameter silicon disk, 250 {mu}m deep disk with a terminal channel width of 100 {mu}m. A Pyrex top allowed for flow visualization. Superficial air and water velocities through the various branch levels were varied from 0.007 m/s to 1.8 m/s and from 0.05 m/s to 0.42 m/s, respectively. Two-phase flow regime maps were generated for each level of the flow network and are ...
Two-phase air-water flows in a microscale fractal-like flow network were experimentally studied and results were compared to predictions from existing macroscale void fraction correlations and flow regime maps. Void fraction was assessed using (1) two-dimensional analysis of high-speed images (direct method) and (2) experimentally determined using gas velocities (indirect method). Fixed downstream-to-upstream length and width ratios of 1.4 and 0.71, respectively, characterize the five-level flow network. Channels were fabricated in a 38 mm diameter silicon disk, 250 ?m deep disk with a terminal channel width of 100 ?m. A Pyrex top allowed for flow visualization. Superficial air and water velocities through the various branch levels were varied from 0.007 m/s to 1.8 m/s and from 0.05 m/s to 0.42 m/s, respectively. Two-phase flow regime maps were generated for each level of the flow network and are well ...
In conventional microtremor prospecting methods, underground structure is estimated using the phase velocity of Rayleigh-wave only. However, it is considered that the underground structure can be estimated at a higher accuracy by using two phase velocities of Rayleigh-wave and Love-wave that directly reflects S-wave velocity structure. Therefore, three-component microtremor array observation of a circle (equilateral triangle) with the maximum radius of 40 to 250 m was carried out at the center of Morioka city. Analysis was carried out by means of extended space with autocorrelation to obtain phase velocities of Love- and Rayleigh-waves. The frequency zone of the obtained Rayleigh-wave phase velocity is 1.5 Hz to 8.6 Hz, and the phase velocity is 2670 m/s to 733 m/s. The frequency zone of the obtained Love-wave phase velocity is 3 Hz to 8.6 Hz, and the phase velocity is 2100 m/s to 412 m/s. The ...
The electrochemical oxidation as a method to destroy drug residues like Aspirin {sup trademark}, tetracycline or gentamicin in water was investigated with C-Anode (modified by manganese oxides) and Pt Anode. The mechanism of Aspirin {sup trademark} and tetracycline oxidation and the influence of the biocide effect was observed using GC-MS and three different microbiological tests. In general the biological availability increases with progressive oxidation of the antibiotics. (orig.)
Meet the NCI Expert: Edward Helton (Center for Biome dical Informatics and Information Technology) Orange County Convention Center: NCI Exhibit Booth #500 20110404T140000Z PRODID -//Microsoft Corporation//Outlook 12.0 MIMEDIR//EN 2.0 METHOD PUBLISH X-MS-OLK-FORCEINSPECTOROPEN TRUE PUBLIC CREATED 20110308T204510Z American
Objective: To develop a computerized method of internal dose estimation on radiation protection. Methods: Based on MIRD mathematic model of the organs and by means of the programming language of MS Visual Basic 6.0, a computer program of dose estimation in internal radiation was developed for radiation protection. Results: The computerized method of dose estimation for internal radiation was completed. Conclusions: This computerized method is very convenient for internal radiation dose estimation of several aspects. It can also be used in radiation accident. (authors)
In recent years the 'Nowcasting Wake Vortex Impact Variables' model NOWVIV has been developed at the Deutsches Zentrum fuer Luft- und Raumfahrt, DLR, to forecast weather parameters in airport environments. The German Meteorological Service, DWD, employs his COSMO-DE model (COnsortium for Small scale Modelling-DEutschland) for operational forecasts in Germany. A systematic comparison of model output from NOWVIV and a derivate of COSMO-DE, named COSMO-FRA, is presented. Both models are centred at Frankfurt Airport with horizontal resolutions of 2.1 km and 2.8 km, respectively. In the DLR Project Wetter and Fliegen the COSMO-FRA model will replace the NOWVIV model and become a key component in the future rapid update cycle for adverse weather predictions at the airports of Frankfurt and Munich. The forecast vertical profiles of runway crosswind, head/tail wind, temperature, and turbulent kinetic energy (TKE) are validated against Wind and Temperature Radar (WTR/RASS) ...
We present a calculation of the charmonium spectrum with three flavors of dynamical staggered quarks from gauge configurations that were generated by the MILC collaboration. We use the Fermilab action for the valence charm quarks. Our calculation of the spin-averaged 1P-1S and 2S-1S splittings yields a determination of the strong coupling, with {alpha}{sub {ovr MS}}(M{sub Z}) = 0.119(4).
...The system recognises the name and confirms it before it starts to dial. To stop the number being dialled say 'cancel'. If ...of the conference : Press the Recall 'R' button and listen for holding dial tone. Select extension or outside number of the person to ...who is going to join the conference Press Recall 'R' to receive dial tone and select '*' and '4'. The call is ...line is faulty and should be reported to the switchboard operators by dialling '0' and giving full details of the fault, the extension ...
Because of good thermal insulation of advanced energetic buildings and their good airtightness the air hygiene is insufficient. A normal ventilation behaviour by window opening consumes too much heating energy. A calculation method is shown taking into account a required air change number, flow rate and indoor air quality as thermal comfort in the rooms occupied by different number of persons. (GL)
The Danish Ministry of Transportation has prepared a national plan of transportation, for the years until 2005. Official policy concerning land, maritime and air transport, personal and cargo transportation, investments and expenditures is outlined. Environmental impacts of energy consumption and air pollution abatement measures are considered. (EG)
The Feynman-#alpha# method was applied to measurement of reactivity and the ability of this method for a real-time reactivity monitoring system was assessed. In the experiment, all measured data by BF_3 detectors were stored in a multi-channel scaler controlled by a personal computer, and they were analyzed to obtain prompt neutron decay constant (#alpha#) and reactivity with consideration of dead time of detector. It was found that #alpha# could be obtained almost in a real-time even for both positive and negative reactivities by the present experimental technique. (author).
Exposure of teachers of physics to X-radiation emitted by instruments which are used for demonstrating rarefied gas discharges during physics lessons at secondary schools is discussed. The measurements performed provide an explicit evidence that an effective, annual exposure dose under the most unfavorable conditions does not exceed admissible levels according to Polish regulations pertaining to persons non-occupationally exposed to ionizing radiation. (author). 3 refs,1 fig.
Involving effects of media, opinion leader and other agents on the opinion of individuals of market society, a trader based model is developed and utilized to simulate price via supply and demand. Pronounced effects are considered with several weights and some personal differences between traders are taken into account. Resulting time series and probabilty distribution function involving a power law for price come out similar to the real ones.
Background: Despite the fact that adverse health effects are not confirmed for exposure to radiofrequency electromagnetic field (RFEMF) levels below the limit values, as defined in the guidelines of the International Commission on Non-Ionizing Radiation Protection, many persons are worried about possible adverse health effects caused by the RF-EMF emitted from mobile phone base stations, or they attribute their unspecific health complaints like headache or sleep disturbances to these fields. Method: In the framework of a cross-sectional study a questionnaire was sent to 4150 persons living in predominantly urban areas. Participants were asked whether base stations affected their health. Health complaints were measured with standardized health questionnaires for sleep disturbances, headache, health complaints and mental and physical health. 3,526 persons responded (85%) to the questionnaire and 1,808 (51%) agreed to ...
This journal includes all formal reports in the NUREG series prepared by the NRC staff and contractors, as well as proceedings of conferences and workshops. The entries in the compilation are indexed for access by title and abstract, contractor report number, personal author, subject, NRC organization, contractor, and licensed facility.
This journal includes all formal reports in the NUREG series prepared by the NRC staff and contractors, as well as proceedings of conferences and workshops. The entries in the compilation are indexed for access by title and abstract, contractor report number, personal author, subject, NRC organization, contractor, and licensed facility.
This conference brought together those persons in the nuclear industry who have a vital interest in the training and licensing of nuclear reactor and nuclear fuel processing plant operators, senior operators, and support personnel for the purpose of an exchange of ideas and information related to the various aspects of training, retraining, examination, and licensing. The document contains 64 papers; each paper was abstracted for the data.
The IAEA Department of Safeguards established a project in 1996 for the year 2000 (Y2K) conversion activities. This project covered assessment, conversion and testing of the software applications, instrument evaluation software, embedded systems and Personal Computer (PC) hardware attached to various equipment. Significant progress has been made in converting the applications and instruments to be year 2000 compliant. At the same time Member states have made an effort as well in converting the systems used jointly at the facilities
... I worked on the Young City Farmers course in 2008, where I was voted the best-spoken bus driver and teacher the participants had ever had!! I am a representative of the University for widening participation and outreach, for my enthusiasm, communication and personal skills. I look forward to meeting you, welcoming you to the College and helping with your learning and progression. Sam Parkes Hi I'm ...
... The award is named for the late Samuelson, a leader and advocate for upward mobility and placement programs to enable visually impaired and blind persons to lead productive lives. The award was created to recognize the career achievements and accomplishments of employees who work in a NIB-associated agency. The Chicago Lighthouse, the company for which Uken works, nominated him based on his exceptional performance at CERL as ...
Today, highly frequent radio waves are regarded as undangerous to man. Diseases seen at radar-technicians during the 2nd World War, however, indicated that microwaves applied in radar systems were hazardous to health. The Russian work medicine has been knowing microwave-caused hazards in industry since the beginning of the thirties. Therefore in some East-European countries there are terms of protection and severe norms of safety for the staying of persons in the radiation sphere of microwaves.
protect digital information, from personal details held on a computer to financial details transmitted over the Internet. Encryption ...in connection with electronic data (Box 2), whether stored on a computer or transmitted over an unsecured network such as ...Encryption tools (usually in the form of computer programs or software) are widely available
From the frequency of diagnostic radiologic examinations and their radiation dose delivered to the population the risk of cancer induction and genetic damage is calculated on the basis of the risk factors given by the ICRP. Thus 0.38 % and 3 % of the total mortality for cancer and leukemia, resp., can be attributed to X-ray diagnostics. Chest examinations alone result in 0.07-0.7 damages per 100,000 persons depending on the imaging technique applied. (author).
Substantial damages at main components of steam turbines do not have to result inevitably in an exchange of the components concerned. Rather a preliminary or final repair is possible which also considers the cause of the damage. An important condition with the technically complex questions is an appropriate qualification and experience of all involved persons. The common task of operators, manufacturers and insurance companies is to preserve the balance from costs, expenditure of time and risk.
Sixty-Hz magnetic field exposures were measured for 45 adult residents of Maine. Thirty of the subjects resided near rights-of-way (ROWs) with either 345- and 115-kV transmission lines, or ROWs with only 115-kV transmission lines; fifteen resided far from any transmission lines. Personal exposure data for a single 24-hour period was acquired with the EMDEX. The EMDEX's event-marker button was used to partition exposures into Home and Away components. Also, three area measurements were taken for each subject during the personal exposure measurement period: (1) 24-hr fixed-site bedroom measurement with a second EMDEX; (2) Spot measurements in at least three rooms of every residence; and (3) Spot measurements outside each residence. Residence near transmission lines highly loaded during the measurement period was associated with increased Home and Total exposure relative to a far-away population. Average exposure level while away from ...
Q. 1. What has it taken to get the LHC project from its beginnings to the verge of first beams? Q. 2. What can be expected to happen on First Beam Day? Q. 3. What happens next in the story? Q. 4. What does this mean to you personally?
A total of 172 persons from nine South Amerindian, three African and one Eskimo populations were studied in relation to the Paired box gene 9 (PAX9) exon 3 (138 base...Full Text Available
BackgroundType 2 Diabetes mellitus (T2DM) affects persons of all ages, while also placing heavy economic burdens on national economies and healthcare systems. The study aims to investigate...Full Text Available
... Bob, who also teaches the Computer Networks and Security course in the Department, has some concerns when it comes to these large monolithic social-networking sites, such as Facebook and MySpace . He would prefer to see people using a more distributed (or federated) approach to avoid single sites being able to gather lots of personal information, including relationships between people . However, most ...
Abstract This article advocates that some form of personal immortality is not only taught in F.D.E. Schleiermacher's Glaubenslehre but is also necessary for the coherence of the same work. The combination of a naturalized account of redemption, a commitment to universal salvation and the realist observation that some never know Christ in this life causes Schleiermacher to posit a certain but content-free afterlife to account for the discrepancy.
This book presents the papers given at a symposium on occupational safety in coal mines. Topics considered at the symposium included human factors, causes and prevention of personal injuries, remote sensing for ground control, respirable dust generation by continuous miners, accident analysis, hazard analysis of mining equipment, coal mine blasting accidents, coal mine respirable dust sampling, and noise in the mining industry.
Passive dosimeters for personal and area radiation monitor in space have been developed mainly for dosimetry in low-earth-orbit (LEO) radiation environments of Space Shuttles and the International Space Station. The responses of several dosimeters have been evaluated by heavy ions and also its variation for individual dosimeter element. (author)
The authors report the personal techniques and the results of CT-guided percutaneous drainage of postoperative abdominal fluid collections. CT-guided percutaneous drainage offers many advantages over surgery: it is less invasive, can be repeated and requires no anesthesia, there are not surgery-related risks and lower morbidity and mortality rates. Moreover, subsequent hospitalization is shorter and costs are consequently reduced. The authors conclude that CT-guided percutaneous drainage is the method of choice in the treatment of postoperative abdominal fluid collections.
No research has compared expressions of weight bias across different subgroups of obese individuals. This study compared attitudes toward and beliefs about obesity in women with and without binge eating disorder (BED) and examined whether these attitudes are related to psychological factors. Fifty obese women with BED were compared with an age- and body mass index (BMI)-matched group of 50 obese women without BED on a battery of established measures of anti-fat attitudes and beliefs about weight controllability and psychological factors (self-esteem, depression, and eating disorder features). The ageand BMI-matched groups did not differ with respect to beliefs about obesity or attitudes toward obese persons, or in self-esteem or depression. Correlational analyses conducted separately within each group revealed that women with BED who reported more favorable attitudes towards obese persons had higher self-esteem and lower levels of depression, ...
Personal monitoring and dose assessment of all radiation workers is an essential regulatory requirement as per radiation safety procedures of AERB and operating stations. The occupational workers of TAPS 1 and 2 and TAPS 3 and 4 are monitored for internal contamination due to high energy gamma emitters by whole body counting
The author reports briefly a noble gas leakage searching process in which a person was contaminated in Daya Bay NPP, the radionuclide causing contamination was ascertained as the daughter product of "8"8Kr, the "8"8Rb; By taking air contamination sampling and measuring the "8"8Rb concentration in the room, the leakage source was predetermined and the leakage rate of primary coolant was estimated
Raman scattering was observed from thin film optical waveguides of cellulose acetate exposed to water vapor from 0% to 100% relative humidity (RH), and from dilute solutions of water in methyl acetate. Spectra of cellulose acetate (CA398, 39.8% acetyl) at low RH and cellulose triacetate (CTA) at low and high RH are consistent with the presence of water monomers that are weakly hydrogen bonded to acetyl C=O groups. Differences between the spectra of water in CA398 and CTA at low RH are attributed to sequential hydrogen bonding involving OH groups in CA398. At high RH, CA398 and CTA (to a lesser extent) show bands attributed to water/water interactions that are similar to those found in sequentially hydrogen-bonded hydrates. CA398 films that are annealed at high temperatures exhibit decreased water/water interactions at high RH. Exposure of CA398 films to D/sub 2/O converts > 90% of all polymer OH groups to OD groups. This indicates that water is accessible to ...
This paper describes a reactor design to facilitate a room-temperature nuclear fusion/fission reaction to generate heat without generating unwanted neutrons, gamma rays, tritium, or other radioactive products. The room-temperature fusion/fission reaction involves the sequential triggering of billions of single-molecule, "6LiD 'fusion energy pellets' distributed in lattices of a palladium ion accumulator that also acts as a catalyst to produce the molecules of "6LiD from a solution comprising D_2O, "6LiOD with D_2 gas bubbling through it. The D_2 gas is the source of the negative deuterium ions in the "6LiD molecules. The next step is to trigger a first nuclear fusion/fission reaction of some of the "6LiD molecules, according to the well-known nuclear reaction: "6Li + D #-># 2"4He + 22.4 MeV. The highly energetic alpha particles ("4He nuclei) generated by this nuclear reaction within the palladium will cause shock and vibrations in the palladium lattices, leading ...
The secondary side corrosion of steam generator tubes is the main degradation of components in operating power plants, strongly impacted by chemistry. This is why EDF has largely studied the chemical parameters in its 56 PWRs which might influence corrosion development. The results of 168 hideout returns of chemical species performed on the French plants allowed to draw conclusions on where chemical species are likely to concentrate in steam generators and on the influence of several contaminants on corrosion processes: sodium, chloride, phosphate, organic compounds, etc... Based on laboratory studies and plants feedback, new chemistry specifications were established and are now applied to EDF units to minimize corrosion and operating costs and to provide a good availability while maintaining an excellent safety. Boric acid is added in the secondary water of the 10 oldest units with Inconel 600 MA tubing, highly sensitive to intergranular stress corrosion cracking. Implementation of ...
A simple and specific method has been developed for the simultaneous determination of the four major Cinchona alkaloids and their dihydroderivatives and pyridoxine hydrochloride (Vitamin B_6) by high-performance liquid chromatography (HPLC) with fluorescence detection (#lambda#_e_m=420 nm with #lambda#_e_x=330 nm). The chromatographic separation was performed on a Phenomenex Prodigy ODS column (5 #mu#m, 250 mmx3.2 mm i.d.), recommended for basic compounds, under isocratic reversed-phase conditions. The method allowed a good peak shape and an effective resolution of the tested compounds. The extraction of alkaloids from the Cinchona succirubra bark was carried out in mild and fast conditions (ambient temperature, 20 min) by ultrasonication. The procedure showed to be advantageous respect to a reference method, which involved Soxhlet extraction. The results were compared statistically by means of the Student's t-test and the variance ratio F-test; no significant ...
The preparation and performance of membranes for application to hydrogen separation from coal-derived gas is described. The membrane material investigated was dense amorphous silica deposited on a suitable support by chemical vapor deposition (CVD). Two types of support materials were pursued. One type consisted of a two-layer composite, zeolite silicalite/{alpha}-Al{sub 2}O{sub 3}, in the form of tubes approximately 0.7 cm in diameter. The other type was porous glass tubes of diameter below 0.2 cm. The first type of support was prepared starting from {alpha}-Al{sub 2}O{sub 3} tubes of 1{micro}m mean pore diameter and growing by hydrothermal reaction a zeolite silicalite layer inside the pores of the alumina at the OD side. After calcination to remove the organic template used in the hydrothermal reaction, CVD was carried out to deposit the final silica layer. CVD was carried out by alternating exposure of the surface with silicon tetrachloride and water vapor. SEM ...
Full text: The transmutation of nuclear waste to reduce the burden on a geological repository is a relevant topic within the Program of Nuclear Safety Research of the Research Centre Karlsruhe. Several studies have confirmed that a high efficiency of transmutation of actinides is reached in fast neutron spectrum reactor system. Therefore, an important effort is dedicated to the study of transmutation strategies with different fast reactors and their associated technologies. Moreover, in international contexts as Generation IV International Forum (GIF) and Sustainable Nuclear Energy Technology Platform (SNETP), fast reactors are considered in the frame of sustainable development of nuclear energy and reduction of waste. The systems that are currently under investigation, in the frame of the different fuel cycle scenarios, are liquid metal cooled and gas cooled fast reactors as well as Accelerator Driven Sub-critical Transmutation devices (ADS). These innovative reactor systems, call for ...
The work presented here demonstrates the ability of proton-transfer-reaction mass spectrometry (PTR-MS) to perform fast-response measurements of volatile organic compounds (VOCs) (including methanol, acetonitrile, acetaldehyde, acetone, PAN-type compounds, alpha- and beta-pinene, nopinone and pinonaldehyde) at the pptv level and its versatile applicability in the field of environmental trace gas analysis. Laboratory and field experiments including various calibration techniques and intercomparisons with other measurement techniques such as gas chromatography, atmospheric pressure chemical ionization and Fourier transformation infrared spectroscopy were performed providing a first characterization of the PTR-MS instrument performance (sensitivity, detection limit, precision, accuracy). Typically a detection limit (S/N=2) of 50 pptv for a 10 s signal integration time, a precision of 5 % and an accuracy in the range between 10 and 25 % were ...
K"#pi#=20"- and 49/2"- yrast isomers have been discovered in "1"7"6Ta and "1"7"7Ta, with meanlives of 1.4 ms and 0.19 ms, respectively. The long meanlives arise from substantial K-hindrance in the "1"7"6Ta case but from spin-trapping in the "1"7"7Ta case. Quasiparticle calculations, which treat the Fermi and pairing energies self-consistently, reproduce the excitation energies of these isomers and the other multi-quasiparticle high-K states observed. Due to blocking, pairing is significantly reduced in the 3-quasiparticle states, the extent depending on the specific configurations. It is completely quenched for both protons and neutrons in the highest seniority states. Yrast traps of even higher spin are predicted to exist in "1"7"6Ta and "1"7"7Ta. ((orig.)).
Carbon stable isotope trichloroethylene ("1"3C TCE) was used to investigate the formation of chloromethane (CM) during the electrolytic dechlorination of trichloroethylene (TCE) at a granular-graphite packed cathode. A method was developed to use a conventional GC/MS to analyze and quantify regular and "1"3C TCE and their dechlorination products. The concentration of a "1"3C compound can be calculated, based on the concentration of its regular counterpart, from the response ratio of two fragments of different mass per charge values from the compounds in a sample and two characteristic MS spectrum ratios: one is the response ratio of the two fragments of the regular compound, and the other is the response ratio of the corresponding fragments of the regular and "1"3C compounds at the same concentrations. The method was used to analyze the regular and "1"3C compounds observed in an experiment of dechlorination in an ammonium acetate solution that ...
First results are presented from an analysis of data from the DRIFT-IIa and DRIFT-IIb directional dark matter detectors at Boulby Mine in which alpha particle tracks were reconstructed and used to characterise detector performance--an important step towards optimising directional technology. The drift velocity in DRIFT-IIa was [59.3 +/- 0.2 (stat) +/- 7.5 (sys)] m/s based on an analysis of naturally-occurring alpha-emitting background. The drift velocity in DRIFT-IIb was [57 +/- 1 (stat) +/- 3 (sys)] m/s determined by the analysis of alpha particle tracks from a Po-210 source. 3D range reconstruction and energy spectra were used to identify alpha particles from the decay of Rn-222, Po-218, Rn-220 and Po-216. This study found that (22 +/- 2)% of Po-218 progeny (from Rn-222 decay) are produced with no net charge in 40 Torr CS2. For Po-216 progeny (from Rn-220 decay) the uncharged fraction is (100 +0 -35)%.
The purpose of the present study was to examine the in vitro effects of low-dose cadmium (Cd) on developing cortical cells. The cortical cells removed from fetuses (embryonic day 15) were treated with 10 nM of Cd for 24 h. The effects of Cd on dendritic and synaptic development were immunocytochemically observed with anti-microtubule associated protein-2 (MAP2) and anti-synapsin I antibodies, respectively. Administration of Cd suppressed dendritic as well as synaptic development at 10 nM. By two-dimensional gel electrophoresis and liquid chromatography-tandem mass spectrometric (LC/MS/MS) analysis, we identified three proteins with different expression after Cd-treatment; dihydropyrimidinase-related protein 2 (DRP-2/CRMP-2), 14-3-3-epsillon and calmodulin (CaM). Though the number of identified proteins was small, these proteins are known to be involved in neuronal development. The present study demonstrated the morphological effects as well as affected proteins in ...
In this work the authors study the stabilization point of a lifted, reacting jet of nitrogen diluted methane in co-flowing air. The jet flow is acoustically forced so as to organize the large scale vortical structures. The validation of the numerical results is possible through a concurrent experimental investigation of a similar planar jet. The use of an acoustically forced planar jet allows for significant savings by the restriction of the computation to two dimensions; the model is otherwise applicable in three dimensions. The authors based their study on the following parameters, which are derived from the experimental setup: a jet width of 1.16 cm, a mean jet velocity of 0.8 m/s, and a coflow velocity of 0.1 m/s. The acoustical forcing is studied at frequencies of 7.5 MHz and 90 MHz, which have been established experimentally as being characteristic of two broad behavioral modes. The authors restrict themselves to five species and the ...
The oscillation experiment of free-electron laser (FEL) was carried at the wave length 488 nm. The space and time properties and power of FEL were investigated. The typical macropulse structure indicated the time interval 20 ms and the pulse width 2 to 3 ms. About 1 ns was necessary to build up FEL. The space distribution of FEL showed beautiful TEM_0_0 mode, TEM_0_1 and TEM_0_2 mode. On the basis of data, 39 #mu#W average power was calculated at 2.9 mA accumulated current per bunch by integrating each response of pixel of CCD camera. The peak power was 1.2 W. In the oscillator, FEL power was average 1.2 W, peak 38 kW. On the electron beam, the stability of head tail was controlled by 6-pole-Quadrupole-6-pole (SQS) system made by an experimental basis. We succeeded the single set test, setting up single set in the ring. The characteristic properties of electron beam evaporation mirror of photo oscillator were studied and then new type photo ...
Empirical birthrate estimates for pulsar binaries depend on the fraction of sky subtended by the pulsar beam: the pulsar beaming fraction. This fraction depends on both the pulsar's opening angle and the misalignment angle between its spin and magnetic axes. Previous estimates use the average value for only two pulsars, i.e. PSRs B1913+16 and B1534+12. We explore how birthrate predictions depend on assumptions about opening angle and alignment, using empirically-motivated distributions to define an effective beaming correction factor, f_{b,eff}. For most known pulsars, we expect f_{b,eff} to be less than 6. We also calculate f_{b,eff} for PSRs J0737-3039A and J1141-6545, applying the currently available constraints for their beam geometry. Our median posterior birthrate predictions for tight PSR-NS binaries, wide PSR-NS binaries, and tight PSR-WD binaries are 89/Myr, 0.84/Myr, and 34/Myr, respectively. For pulsars with spin period between 10 ms and 100 ...
Proteomic changes in proteins secreted by human hepatocellular carcinomas (HepG2) cells exposed to butyl benzyl phthalate (BBP) were evaluated. HepG2 cells were treated with three different concentrations of BBP (0, 10, or 25 ?M) for 24 or 48 h. Following incubation, the cells were subjected to proteomic analysis using two different pI ranges (4-7 and 6-9) and large-size two-dimensional gel electrophoresis. Results showed resolution of a total of 2776 protein spots. Of these, 29, including 19 upregulated and 10 downregulated proteins, were identified by electrospray ionization-mass spectrometry-mass spectrometry (ESI-MS/MS). Among these, the identities of cystatin C, Rho guanine nucleotide dissociation inhibitor, gelsolin, DEK protein, Raf kinase inhibitory protein, triose phosphate ...
Laser-induced change is studied of the optical absorption and luminescence due to F-H pairs generated by an electron pulse in SrF_2. It is found that laser irradiation near 2.34 eV at a delay of 26 #mu#s after an electron pulse by which F-H pairs are generated reduces the component I of the pairs that has a decay time of 59 #mu#s and optical absorption bands at 2.34 and 4.13 eV and enhances the component II that has a decay time of 7.7 ms and has optical absorption bands at 2.7 and 3.35 eV. Laser irradiation near 2.7 eV at a delay of 4 ms after the electron pulse is found to induce the reverse reaction. Studies of dichroism of the laser-induced reduction and enhancement of the optical absorption bands and the luminescence reveal that the direction of the #SIGMA#-#SIGMA# transition of the F_2"- molecular ion is converted by the transformation from I to II and vice versa. It is suggested that the component I corresponds to the F-H pairs at ...
Site measurements were collected at Mount John University Observatory in 2005 and 2007 using a purpose-built scintillation detection and ranging system. $C_n^2(h)$ profiling indicates a weak layer located at 12 - 14 km above sea level and strong low altitude turbulence extending up to 5 km. During calm weather conditions, an additional layer was detected at 6 - 8 km above sea level. $V(h)$ profiling suggests that tropopause layer velocities are nominally 12 - 30 m/s, and near-ground velocities range between 2 -- 20 m/s, dependent on weather. Little seasonal variation was detected in either $C_n^2(h)$ and $V(h)$ profiles. The average coherence length, $r_0$, was found to be $7 \\pm 1$ cm for the full profile at a wavelength of 589 nm. The average isoplanatic angle, $\\theta_0$, was $1.0 \\pm 0.1$ arcsec. The mean turbulence altitude, $\\bar{h_0}$, was found to be $2.0\\pm0.7$ km above sea level. No average in the Greenwood frequency, $f_G$, ...
Since living things began their activities on the earth, the extermination of living things in large number on global scale occurred twice 230 million years ago (P-Tr boundary) and 65 million years ago (K-T boundary). As to the cause of exterminating living things in short period, there are volcano eruption theory, meteorite collision theory and so on, but still it is not decided. Therefore, as to the strata of P-Tr boundary in south-western part of China where it has been known the preservation of P-Tr strata is especially good, the existence of elements was measured by instrument neutron activation analysis and ICP-MS, and the state of change was examined. According to the results, the change occurred at the P-Tr boundary on the earth, and further, the possibility of meteorite collision by paying attention to Ir were examined. The samples, the neutron activation analysis, the ICP-MS and the results are reported. The distinction by strata and ...
Cerebral maturation in the human fetal brain was investigated by in utero localized proton magnetic resonance spectroscopy (MRS). Spectra were acquired on a clinical MR system operating at 1.5 T. Body phased array coils (four coils) were used in combination with spinal coils (two coils). The size of the nominal volume of interest (VOI) was 4.5 cm"3 (20 mm x 15 mm x 15 mm). The MRS acquisitions were performed using a spin echo sequence at short and long echo times (TE = 30 ms and 135 ms) with a VOI located within the cerebral hemisphere at the level of the centrum semiovale. A significant reduction in myo-inositol and choline and an increase in N-acetylaspartate were observed with progressive age. The normal MR spectroscopy data reported here will help to determine whether brain metabolism is altered, especially when subtle anatomic changes are observed on conventional images. Some examples of impaired fetal brain development studied by MRS are ...
We consider relay selection technique in a cooperative cellular network where user terminals act as mobile relays to help the communications between base station (BS) and mobile station (MS). A novel relay selection scheme, called Joint Uplink and Downlink Relay Selection (JUDRS), is proposed in this paper. Specifically, we generalize JUDRS in two key aspects: (i) relay is selected jointly for uplink and downlink, so that the relay selection overhead can be reduced, and (ii) we consider to minimize the weighted total energy consumption of MS, relay and BS by taking into account channel quality and traffic load condition of uplink and downlink. Information theoretic analysis of the diversity-multiplexing tradeoff demonstrates that the proposed scheme achieves full spatial diversity in the quantity of cooperating terminals in this network. And numerical results are provided to further confirm a significant energy efficiency gain of the proposed ...
Two-layered dissolving microneedles of which acral portion contained leuprolide acetate (LA) as solid dispersion were prepared with sodium chondroitin sulfate as the base and the systemic absorption efficiency of LA was studied in rats after administration to their abdominal skin. A patch contained 100 dissolving microneedles of which length and basement diameter were 469.8+/-4.7mm and 284.5+/-9.8mm, where LA content was 14.3+/-1.6mg. In vitro dissolution experiment showed that LA was released from dissolving microneedle patch within 3min. LA was stable in the patch, % recoveries for 3 months were 102.2+/-1.9-95.3+/-1.9%. One and half-patch of LA dissolving microneedles were administered to the rat skin and plasma LA concentrations were measured by LC-MS/MS. Plasma LA concentrations increa...
Remotely-operated SHRIMP dating of zircon is an interesting alternative for dating of zircon crystals. Although it does not represent any technical progress of the geochronological method using the U-Pb system in zircon it is a very useful and cheap facility. The procedure was first used for mass spectrometric analyses involving two international laboratories in Sao Paulo, Brazil and Beijing, China. It was applied to samples of three gneiss-migmatitic rocks from the Ita quarry in the Atuba Complex (located between the Luis Alves and the Apiai Domain) to test previous controversial hypotheses about its evolution. The presence of important archaean and paleo proterozoic components in the complex is confirmed by analyses of zircon found in probably neo proterozoic leucosomes. Diorite intrusion also occurred during the neo proterozoic, associated with the 0.6Ga continental collisions involved in the assembly of Gondwana. The determination of Hf isotope ratios by ...
Three-flavor lattice QCD simulations and two-loop perturbation theory are used to make the most precise determination to date of the strange-, up-, and down-quark masses, $m_s$, $m_u$, and $m_d$, respectively. Perturbative matching is required in order to connect the lattice-regularized bare- quark masses to the masses as defined in the \\msbar scheme, and this is done here for the first time at next-to-next-to leading (or two-loop) order. The bare-quark masses required as input come from simulations by the MILC collaboration of a highly-efficient formalism (using so-called ``staggered'' quarks), with three flavors of light quarks in the Dirac sea; these simulations were previously analyzed in a joint study by the HPQCD and MILC collaborations, using degenerate $u$ and $d$ quarks, with masses as low as $m_s/8$, and two values of the lattice spacing, with chiral extrapolation/interpolation to the physical masses. With the new perturbation theory ...
The report details the results of a series of large-scale experiments where small coal fires were used to ignite conveyor belting at air velocities ranging from 0.76 m/s to 6.1 m/s. In the tests, electrical strip heaters imbedded within a pile of coal were used to heat the coal to a point of flaming ignition. The flaming coal subsequently ignited conveyor belting located approximately 5 to 10 cm above the coal pile. During the tests, temperature, CO, and smoke levels were continuously measured in order to determine both alarm time and level as the fire intensity progressed through the stages of smoldering coal, flame coal, and flaming coal plus flaming belt. Analysis of the data leads to certain conditions of air velocity and sensor alarm levels that are required for early detection of conveyor belt entry fires. Two nomographs are presented which define sensor alarm levels and sensor spacings as a function of belt entry cross-sectional area and ...
Electrification of Teflon (PTFE) particles pneumatically transported while repeating collision with the wall is different from the cases of nylon 66 or PMMA. PTFE is known as negatively charging substance. Extremely little electrification was found when vertically colliding to the wall. By experiments, it was found that: 1. In the case of vertical collision, electrification was extremely low. 2. Chareg amount by collision increases as v cos increases when it is less than 7.5 m/s in a condition that a horizontal component of a collision speed is present. When v cos is more than 7.5 m/s, the charge approaches that of vertical collision. 3. Measured value of collision area roughly coincided with the result of calculation using an equation based on the assumption that the deforamtion depended only on the vertical component of the collision speed. 4. Charge density gets larger for less v cos and more v sin . Charge density of PTFE which was measured ...
Holmium doped barium based hexaferrites BaFe_1_2_-_2_xHo_2_xO_1_9 with (x = 0.0-1.0) were synthesized by solid state reaction method. Structural and magnetic characterization of these ferrites provide significant information about their reactive physical properties. X-ray analysis reveals that in all samples M-type structure exist with few secondary phases. Scanning electron microscope revealed the grain size of the specimen. The results show that grain size decreases with the substitution degree of Holmium. Thus rare earth element Holmium Ho"3"+ acts as a grain growth inhibitor. The magnetic hysteresis loops show the variation in the values of magnetic parameters like saturation magnetization (M_s), remanent magnetization (M_r) and coercivity (H_c) were observed by changing Ho"3"+ content in BaFe_1_2_-_2_xHo_2_xO_1_9 ferrites. Coercivity showed a maximum value of 2230 Oe for (x = 0.4) and then decreasing trend were observed in the values of H_c, M_r and ...
Dynamic behaviors of gaseous sulfur-containing compounds evolved from pyrolysis of six Chinese coals were studied in the temperature range of up to 800{sup o}C under N{sub 2} and H{sub 2}. The released amount of total sulfur-containing gases was traced by an online flame photometric detector (FPD). Simultaneously, the changes of different sulfur forms, including H{sub 2}S, SO{sub 2}, COS and CS{sub 2}, also were investigated using an online mass spectrometer (MS). FPD results show that the effect of H{sub 2} on gaseous sulfur evolved is complex, which promoted certain peak and suppresses other peaks. Based on the data from MS, it is suggested that a series of competitive reactions between active sulfur and other active matters during pyrolysis may impact on the sulfur form in gas phase. Interactions between active sulfur-containing intermediates and the coal matrix are attributed to be the main factor determining the dynamic behavior.
An analytical method was developed for the determination of eleven agrochemicals [abamectin (as B1a), bifenazate, bifenthrin, carfentrazone-ethyl, cymoxanil, hexythiazox, imidacloprid, mefenoxam, pymetrozine, quinoxyfen, and trifloxystrobin] in dried hops. The method utilized polymeric and NH2 solid phase extraction (SPE) column cleanups and liquid chromatography with mass spectrometry (LC-MS/MS). Method validation and concurrent recoveries from untreated dried hops ranged from 71 to 126% for all compounds over three levels of fortification (0.10, 1.0, and 10.0 ppm). Commercially grown hop samples collected from several field sites had detectable residues of bifenazate, bifenthrin, hexythiazox, and quinoxyfen. The control sample used was free of contamination below the 0.050 ppm level for all agrochemicals of interest. The limit of quantitation and limit of detection for all compounds were 0.10 and 0.050 ppm, respectively. PMID:18593182
The object of this research is the evaluation of the performance of ultra high speed relays (UHSR's) used for protection of a-c transmission lines. For purposes of this report, these are relays whose response time is less than a quarter of a cycle of the 60 Hz wave (i.e. 4.167 ms.). To identify relaying schemes that may comply with this definition, a literature survey was undertaken. The selected relays were studied in detail and modeled on a digital computer. A theoretical description of these relays is presented. Records of real transient data as well as of simulated data were used as input to the digital models of relays. The real data were recorded by means of monitoring stations connected to the Florida Power and Light Company transmission lines. The simulated data were obtained by modeling the relevant parts of the utility's transmission system using a University of British Columbia simplified version of the well known Electromagnetic ...
A force measurement technique has been developed for large-scale aerodynamic models with a short test time. The technique is based on direct acceleration measurements, with miniature accelerometers mounted on a test model suspended by wires. Measuring acceleration at two different locations, the technique can eliminate oscillations from natural vibration of the model. The technique was used for drag force measurements on a 3 m long supersonic combustor model in the HIEST free-piston driven shock tunnel. A time resolution of 350 #mu#s is guaranteed during measurements, whose resolution is enough for ms order test time in HIEST. To evaluate measurement reliability and accuracy, measured values were compared with results from a three-dimensional Navier-Stokes numerical simulation. The difference between measured values and numerical simulation values was less than 5%. We conclude that this measurement technique is sufficiently reliable for measuring aerodynamic force ...
This paper presents a comprehensive study of pesticide levels and bio-accumulation characteristics in human adipose tissues among residents of Southeast China. A large number of adipose samples (n=633) were selected for 58 pesticides and were analyzed by high sensitive Gas Chromatography-Tandem Mass Spectrometry (GC-MS/MS). The results showed that POPs pesticides were frequently detected, including 2,4prime-DDD, 2,4prime-DDE, 2,4prime-DDT, 4,4prime-DDD, 4,4prime-DDE, 4,4prime-DDT, a-HCH, b-HCH, g-HCH, d-HCH, hexachlorobenzene (HCB), and mirex. Other detected pesticide species were dicofol, methamidophos and chlordimeform, which have rarely been reported. Comparing to different countries, the concentrations of total DDT and HCH in these three Chinese southeastern sites were in the middle ra...
T_2 weighted ultra-short turbo spin echo sequences were used in five individuals with variations in echo times, delayed triggering and echo intervals. To reduce movement artifacts all examinations were carried out with ECG and respiratory triggering. The sequences giving optimal image quality were then employed in 19 patients having various pulmonary abnormalities. Image resolutions, artifacts, image contrasts and diagnostic value were then judged by two observers and compared with CT. In the first study, a diastole-triggered UTSE sequence with the shortest echo proved optimal (T_E=90 ms, T_R=2-4 s, echo=9 ms, turbo factor=19). In the patient series studied, MRT was inferior to CT with regard to resolution and number of artifacts, but better in respect of contrast and diagnostic value. Using UTSE of the lung, MRT can produce images of good quality. Compared with CT, contrast is better with MRT, offering diagnostic advantages for MRT. ...
Bubbly and slug flows have been analyzed using the afore-mentioned techniques. An image series of bubbly-slug flow is shown. The image separation time is 17 ms, and the total flow length is {approx} 10 cm. A circular eddy pattern that follows the slug can be readily seen and tracked, although reliability is low due to motion in the transverse direction. This motion also adds considerable error to the velocity measurements using image recognition technique. This will increase the reliability and accuracy of the tracking method.
Experimental investigations of the turbulence characteristics of the air flow above the wave surface of the film in the horizontal rectangular channel in the 5-20 m/s velosity range of the air rate change (Reynolds number for the air 120O0-48000, 100-1000 for the film) are carried out. It is shown that intensities of turbulent pulsations of the rate increase with the growth of liquid flow rate in the film especially in the region of large squall waves. The experimental results on the pulsations are presented in the dimensionless form by a universal dependence. Distributions of tangentials of turbulent stresses above the film are obtained, turbulent stresses are compared with friction losses at the phase interface.
This paper reports on the electron current to a Langmuir probe in a moving high-pressure plasma. The plasma is an atmospheric-pressure propane flame, and the probe's speed relative to the plasma is varied from 10 to 30 ms"-"1. The current is linearly dependent on the speed and appears to be comprised of two components - one driven by diffusion and the other by convection. A model is devised which can be used to measure the electron density. By comparing the density computed from this model to that measured from the ion current, it has been possible to measure the electron mobility in the flame gases. The value obtained here is in good agreement with theoretical calculations found in the literature.
The aim of this study was to investigate the photodegradation of the antiemetic drug metoclopramide. Metoclopramide aqueous solutions were photoirradiated at 254nm under argon atmosphere. Irradiated metoclopramide solutions were analyzed by high performance liquid chromatography-ion trap mass spectrometry in order to characterize photolysis products. Rapid decrease in metoclopramide purity, following first-order kinetic, was observed following irradiation. The structures of 18 photolysis products were tentatively identified based on their mass spectra and fragmentation. The main degradation mechanism was scission of the chlorine which could be followed by polymerization of the resulting products since dimeric and trimeric products were observed.
A three dimensional sea-land breeze model has been employed for the study on the inland penetration of sea breeze around Wolsung NPP site. In this study, the sea breeze simulation was carried out under the weak northwesterly geostrophic wind (3.2 m/s, 339 .deg.) at 850 hPa in Spring. The results showed that sea breezes developed near Wolsung site penetrated into about 20 km inland under the weak northwesterly geostrophic wind in Spring. This result agreed with observation data around Wolsung site on May 1996.
A three dimensional sea-land breeze model has been employed for the study on the inland penetration of sea breeze around Wolsung NPP site. In this study, the sea breeze simulation was carried out under the weak northwesterly geostrophic wind (3.2 m/s, 339 .deg.) at 850 hPa in Spring. The results showed that sea breezes developed near Wolsung site penetrated into about 20 km inland under the weak northwesterly geostrophic wind in Spring. This result agreed with observation data around Wolsung site on May 1996.
We discuss the inclusive production of D{sup *{+-}} mesons in {gamma}p collisions at DESY HERA, based on a calculation at next-to-leading order in the general-mass variable-flavor-number scheme. In this approach, MS subtraction is applied in such a way that large logarithmic corrections are resummed in universal parton distribution and fragmentation functions and finite mass terms are taken into account. We present detailed numerical results for a comparison with data obtained at HERA and discuss various sources of theoretical uncertainties. (orig.)
Purpose: In vitro evaluation of possible deflection and heating of present-day prosthetic heart valves, 12 technical and 5 biological, were investigated using a 1.5 Tesla Siemens Vision system. Deflection was measured at the edge of a 1.5 Tesla superconducting magnet. Each valve was then submerged in a vial of a 1/1 electrolyte solution and temperature was measured before and after imaging with a turbo-spin-echo sequence (TR 5200 ms, TE 138 ms, Flip angle 180 C, acquisition time 10.5 minutes, length of echo train 29). MR imaging was performed with phase encoding parallel and perpendicular to the plane of the valves. Results: None of the investigated prosthetic heart valves was deflected. The maximal observed temperature rise was 0.5 C. During MR investigation of the prostheses, artifacts caused by metallic parts were less evident using a spin-echo sequence than a gradient-echo sequence. Conclusions: Patients with the tested present-day ...
The paper presents experimental investigations of main features of plasma surface interaction and energy transfer to the material surface in dependence on plasma heat loads. The experiments were performed with QSPA repetitive plasma pulses of the duration of 0.25 ms and the energy density up to 2.5 MJ/m2. Surface morphology of the targets exposed to QSPA plasma screams is analyzed. Relative contribution of the Lorentz force and plasma pressure gradient to the resulting surface profile is discussed. development of cracking on the tungsten surface and swelling of the surface are found to be in strong dependence on initial temperature of the target.
This paper reports area and time dependent dielectric breakdown distributions of ethylene glycol and water solutions cooled to -23/sup 0/C. Electrode areas of 80, 400, 2000, and 10,000 cm/sup 2/ spaced 1 cm apart were repeatedly stressed with voltage pulses exponentially decaying in 5 to 20 ms. Approximately 80,000 measurements concentrated at electric field strengths near the 1% breakdown probability region of the samples were taken in order to obtain statistically accurate data on the dielectric strength of this liquid.
Here we report detailed dielectric studies carried out on a Barium strontium titanate (BST) (95:5) composition. The material was synthesized by conventional ceramic method and microwave processing, and the later technique resulted in material with high density, improved microstructure and dielectric properties. The dielectric properties were studied as a function of frequency and temperature and well-defined ferroelectric behavior of first order transition was observed. It follows Curie-Weiss law above transition temperature (paraelectric region). Curie temperature is slightly higher for microwave sintered (MS) material.
A chemically assisted micro-beam etching system for 3D microanalysis was designed. Using chemically assisted ion beam etching (CAIBE) method with FIB shave-off scanning, about several hundred micrometers clean cross-section will be acquired in a few hours. We use focused ion beam (FIB) and electron beam (EB) as micro-beams, halogen or halide mainly as reactive gases. The apparatus was manufactured based on this concept. We found that the FIB, Q-MS and SED worked as expected. The instrumentation has been completed.
A two-cycle process using O{Phi}CMPO and HDEHP as extractants to achieve an alpha decontamination factor of HLLW greater than 10{sup 3} together with a reduction of the lanthanides/americium weight ratio by a factor of about 200 is considered. Experimentally measured distribution ratios have been employed as input data of a suitable computer code to define operating conditions and M/S stage numbers of a process flow-sheet able to meet the above-mentioned objectives.
T{sub 2} weighted ultra-short turbo spin echo sequences were used in five individuals with variations in echo times, delayed triggering and echo intervals. To reduce movement artifacts all examinations were carried out with ECG and respiratory triggering. The sequences giving optimal image quality were then employed in 19 patients having various pulmonary abnormalities. Image resolutions, artifacts, image contrasts and diagnostic value were then judged by two observers and compared with CT. In the first study, a diastole-triggered UTSE sequence with the shortest echo proved optimal (T{sub E}=90 ms, T{sub R}=2-4 s, echo=9 ms, turbo factor=19). In the patient series studied, MRT was inferior to CT with regard to resolution and number of artifacts, but better in respect of contrast and diagnostic value. Using UTSE of the lung, MRT can produce images of good quality. Compared with CT, contrast is better with MRT, offering diagnostic advantages for ...
The thesis explains the development of a mass spectrometerical isotope dilution analysis (MS/DA) for determining trace amounts of Tc. The Tc-97 isotope has been prepared by in-core irradiation of Ru of natural isotopic composition, and used as the indicator isotope. For separation of Tc-97 from the Ru matrix, a method has been developed to quantitatively separate Tc-97 from a high Ru surplus. For determining the isotope ratio for the MS/DA, a mass spectrometrical measuring technique has been found which allows reproducible measurement of the Tc-99/Tc-97 isotope ratio. Positive and, for the first time, also negative thermoionisation has been used as a method of selective ionisation of Tc. The applicability of the MS/DA for Tc trace analysis has been verified using two Al foils doped with Tc-99 or Mo-98, respectively. These have been irradiated in a nuclear reactor, the irradiation of Tc-99 yielding Ru-100, and irradiation of ...
Full text: A novel protocol based on electrospray ionization (ESI) multiple stage high capacity ion trap (HCT) mass spectrometry (MS) was developed for glycosphingolipidomic surveys. The method was optimized for detailed structural elucidation of human brain gangliosides and particularly applied to human hippocampus-associated structures. The multiple stage MS experiments allowed for a complete structural characterization of GM1 ganglioside species, which was achieved by elucidation of the oligosaccharide sequence, identification of the GM1 a structural isomer from the data upon sialic acid localization along the sugar backbone and determination of the d18:1/18:0 of fatty acid/sphingoid base composition of the ceramide moiety. The methodology developed here is of general practical applicability for glycolipids and represents a step forward in the implementation of the advanced and most modern MS methods in glycomics. ...
The aim of this work was to develop several strategies and software-packages for the evaluation of in-vivo-data of the human brain, which were acquired with high-resolution 1H-MRSI at 1.5 and 3 T. Several studies involving phantoms, volunteers and patients were performed. Quality assurance studies were conducted in order to evaluate the reproducibility of the applied MR-techniques at both field strengths. A qualitative comparison-study between MRSI-data from a 1.5 T clinical MR-scanner and a 3 T research MR-scanner showed the advantages of the more advanced MRSI sequences and higher field strength (3 T). A study involving patients with primary brain tumours (gliomas) was performed in cooperation with the Department of Neurosurgery (University of Erlangen-Nuremberg). The methods developed in the course of this study, such as the integration of MRS-data into a stereotactic-system, the segmentation of metabolic maps and the correlation with histopathological findings represent a package ...
Abstract in english Previous studies have shown that women are more emotionally expressive than men. It is unclear, however, if women are also more susceptible to the emotional modulation of behavior imposed by an affective stimulus. To investigate this issue, we devised a task in which female subjects performed six sequential trials of visual target detection following the presentation of emotional (mutilation and erotic) or neutral pictures (domestic utensils and objects) and compared the (more) data obtained in the present study with those described in a previous study with male subjects. The experiment consisted of three blocks of 24 pictures and each block had an approximate duration of 4 min. Our sample consisted of 36 subjects (age range: 18 to 26 years) and each subject performed all blocks. Trials following the presentation of mutilation pictures (283 ms) had significantly slower reaction times than those following neutral (270 ms) ...
The purpose of this thesis is to study the behaviour of the simultaneous flow of oil and water in horizontal pipes. In this connection, two test facilities are used. Both facilities have horizontal test sections with inner pipe diameters equal to 2 inches. The largest facility, called the model oil facility, has reservoirs of 1 m{sub 3} of each medium enabling flow rates as high as 30 m{sub 3}/h, which corresponds to mixture velocities as high as 3.35 m/s. The flow rates of oil and water can be varied individually producing different flow patterns according to variations in mixture velocity and input water cut. Two main classes of flows are seen, stratified and dispersed. In this facility, the main focus has been on stratified flows. Pressure drops and local phase fractions are measured for a large number of flow conditions. Among the instruments used are differential pressure transmitters and a traversing gamma densitometer, respectively. The flow patterns that ...
The adsorption equilibria of Kr, Xe and N{sub 2}, which are constituents of the off-gas from nuclear reprocessing processes, on representative adsorbents (Molecular Sieve 5A (MS5A) and activated charcoal) were studied. Adsorption experiments were conducted in the temperature range of 77 to 323 K using a packed bed column. The adsorption isotherms for the activated charcoal adsorbent were successfully correlated by the vacancy solution model. The adsorption isotherms for the MS5A adsorbent were properly correlated by the Langmuir model and the vacancy solution model. The adsorption experiments for the binary component systems (Kr-Xe, Kr-N{sub 2} systems) were also performed, and the results suggest that the coexistence of Xe greatly inhibits the adsorption of Kr. The coexistence of large amounts of N{sub 2} was also found to inhibit the adsorption of Kr. The experimental results for the adsorption equilibrium of binary component systems on the ...
Previous studies have found that classrooms are often inadequately ventilated, with the resultant increased risk of negative impacts on the pupils. This paper describes a series of field measurements that investigated the indoor air quality, thermal comfort and acoustic performance of nine recently built secondary schools in England. The most significant conclusion is that the complex interaction between ventilation, thermal comfort and acoustics presents considerable challenges for designers. The study showed that while the acoustic standards are demanding it was possible to achieve natural ventilation designs that met the criteria for indoor ambient noise levels when external noise levels were not excessive. Most classrooms in the sample met the requirement of limiting the daily average CO{sub 2} concentration to below 1500 ppm but just a few met the need to readily provide 8 l/s per person of fresh air under the easy control of the occupants. It would seem that ...
The medical applications of radiation comprise three main fields namely: Diagnostic Radiology, Radiotherapy and Nuclear Medicine. With the new weighting factors of ICRP (IC91a) the effective dose due to medical applications can be established. I is common to separate the effective dose into the genetic part and the somatic part, SED. In dealing with gonad doses it is important to account for the age of the person at the time of exposure as this will influence the number of children still to be expected from that person. The resulting dose will then be called the genetically significant dose, GSD. In a similar fashion this age factor will be important in considering the chance of tumor induction. The age of patients differs considerably from the average age of the general population. This age difference has to be accounted for if a comparison is to be made with other sources of radiation. This justifies establishing a somatically significant ...
For satisfaction of international growing demand for electrical energy it is impossible to ignore contribution of nuclear power. With an expected lifespan for nuclear plants estimated to 50-60 years of operation (years for decommissioning added), there is a need for a steady multi-generational stream of competent staff to ensure safe operations of nuclear plants. It is incumbent to governments to invest in education, research, and training for the three to five generations of people who will construct, operate and eventually decommission nuclear plants over the duration of their life cycle. To develop sustained nuclear programs it is necessary to carry out a lot of major problems, but three of them look like as most important: 1. Training a qualified and competent personal to ensure all nuclear activities; 2. Multilateral approach for nuclear fuel cycle, with a guaranteed framework for ensuring the supply of NPP owners with the necessary nuclear fuel; 3. ...
This guide explained the requirements for Off-Road Compression Ignition Engine Emission Regulations established under the Canadian Environmental Protection Act. The regulations are enforced by Environment Canada, which authorizes and monitors the use of the national emissions mark. The regulations prescribe standards for off-road engines that operate as reciprocating, internal combustion engines, other than those that operate under characteristics similar to the Otto combustion cycle and that use a spark plug or other sparking device. The regulations apply to engines that are typically diesel-fuelled and found in construction, mining, farming and forestry machines such as tractors, excavators and log skidders. Four different types of persons are potentially affected by the regulations: Canadian engine manufacturers; distributors of Canadian engines or machines containing Canadian engines; importers of engines or machines for the purpose of sale; and ...
This guide explained the requirements for Off-Road Compression Ignition Engine Emission Regulations established under the Canadian Environmental Protection Act. The regulations are enforced by Environment Canada, which authorizes and monitors the use of the national emissions mark. The regulations prescribe standards for off-road engines that operate as reciprocating, internal combustion engines, other than those that operate under characteristics similar to the Otto combustion cycle and that use a spark plug or other sparking device. The regulations apply to engines that are typically diesel-fuelled and found in construction, mining, farming and forestry machines such as tractors, excavators and log skidders. Four different types of persons are potentially affected by the regulations: Canadian engine manufacturers; distributors of Canadian engines or machines containing Canadian engines; importers of engines or machines for the purpose of sale; and ...
For the last years, time-series mining has become a challenging issue for researchers. An important application lies in most monitoring purposes, which require analyzing large sets of time-series for learning usual patterns. Any deviation from this learned profile is then considered as an unexpected situation. Moreover, complex applications may involve the temporal study of several heterogeneous parameters. In that paper, we propose a method for mining heterogeneous multivariate time-series for learning meaningful patterns. The proposed approach allows for mixed time-series -- containing both pattern and non-pattern data -- such as for imprecise matches, outliers, stretching and global translating of patterns instances in time. We present the early results of our approach in the context of monitoring the health status of a person at home. The purpose is to build a behavioral profile of a person by analyzing the time variations of several ...
Anatomical specimens and normal persons were studied by gradient echo MR imaging to determine the influence of different echo times (TE) on bone marrow contrast. First of all, six normal persons were studied to determine specific echo times for in-phase and opposed-phase states. Using different sequences bone marrow contrast in isolated femoral bones was determined and compared to results of pathological exams. Red bone marrow had no signal on opposed-phase images; contrast between red and yellow marrow was higher on opposed-phase than on in-phase images. Bone marrow lesions can be expected to be visualised with high signal on opposed-phase images; this technique should be especially suited for MR imaging of bone marrow. (orig.).
Divided into three sections, this paper briefly presents Kohlberg's theory of moral reasoning; surveys some key research relating childrearing practices to adolescents' social competence, including moral reasoning; and reports research findings concerning the value systems adolescents develop. The first section characterizes preconventional, conventional, and postconventional morality and explores ways of promoting the development of a mature concept of justice, which includes role taking and living in a "just community." The second section focuses on aspects of social learning, which include authoritative parenting, inductive discipline, argumentative discourse, and tradition-based upbringing. In addition, this section explores socialization practices that hinder the development of mature moral reasoning. Focusing initially on characteristics of alienated youth and parental influences on such youth, the third section describes studies investigating the values development of New York ...
The goal of this study is to estimate the relevance and Influence of the Existing Regulation and the RI-PBR to the institutionalization of the regulatory system. This study reviews the current regulatory system and the status of the RI-PBR implementation of the US NRC and Korea based upon SECY Papers, Risk Informed Regulation Implementation Plan (RIRIP) of the US NRC and other domestic studies. In order to investigate the perceptions, knowledge level, ground for the regulatory change, a survey was performed to Korean nuclear utilities, researchers and regulators on the perception on the RIR. The questionnaire was composed of 50 questions regarding personal details on work experience, level of education and specific field of work ; level of knowledge on the risk informed performance based regulation (RI-PBR); the perception of the current regulation, the effectiveness, level of procedure, flexibility, dependency on the regulator and personal ...
A study on brain CT was made in 20 cases of typical endemic cretinism and 15 cases of normal persons. These patients from severely iodine deficient area were diagnosed as neurological endemic cretinism characterized by severe mental retardation with impairment of hearing, speech, neuromotor, etc. to varying degrees. The brain CT showed that there were many and deep depressions in cerebral cortex, especially in frontal and parietal lobes of some cretins, the lateral ventricle system was dilated, particularly in posterior part of it, and the interhemisphere fissure, lateral fissure and subarachnoid cisterns were also expanded. The CT value of cortex was higher and white matter was lower than that of normal persons. In some severe cases, the two hemispheres of brain were not the same in size. These findings above indicated that these endemic cretins had a severe retardation of brain development including cerebral cortex and white matter. In ...
A personal computer based single specimen unloading technique has been demonstrated using a nuclear grade pressure vessel material, A533B Class I steel, and an #alpha#-#beta# titanium alloy, CORONA-5. Experimental parameters investigated in the case of steel include the effect of test temperature, loading rate and neutron irradiation. Results revealed the effect of dynamic strain aging (DSA) as a drop in the critical crack initiation fracture toughness (Jsub(q)); the minimum in Jsub(q) shifts to higher temperatures at higher test speeds as predicted from DSA models. In CORONA-5, the effects of microstructure and heat treatment for two different sizes of equiaxed #alpha# morphology in a #beta#-matrix heat treated to different yield strengths were investigated. It is found that the observed higher values of Jsub(q) and tearing modulus result from a greater tortuosity of the crack path and ease of crack blunting. The largest increase in Jsub(q) occurred in fine ...
In this thesis, increased hemicellulose retention during kraft pulping has been studied. The work has been divided into three parts: i) Development of an accessible and reliable method for determination of carbohydrate composition of kraft pulps ii) Investigation of the composition and molecular mass distributions of the carbohydrates in kraft pulps with increased hemicellulose content iii) Investigation of the effect of increased hemicellulose content on the sheet properties of kraft pulps with increased hemicellulose content. A method for carbohydrate determination was developed. In this method, enzymes are used to hydrolyse the pulp into monosaccharides. A relatively mild acid hydrolysis is performed prior to detection on an HPLC with an RI-detector. The pulp is not derivatized and no pre-treatment (mechanical or chemical) is needed to determine the carbohydrate composition using the method developed here. Peak deconvolution software is used to improve the accuracy. Polysulphide and ...
In this study, e-waste flows of five large home appliances (color televisions, refrigerators, washing machines, personal computers, and air conditioners) in Vietnam are investigated. A social survey was performed to investigate the situation on using appliances in households as well as on the disposal of appliances by the first users. Future quantities of e-waste were estimated using a model that combines use of the Weibull distribution, the logistic function, and the population balance model. It was forecast that about 3.86 million appliances, or 114 000 tons, will be discarded in 2010, and about 17.2 million appliances, or 567 000 tons, in 2025, showing a rapid increase of e-waste in the near future.
The discussion focuses on the ways in which the 3 panelists in their lives and work embody fourth wave feminism, which combines politics, psychology, and spirituality in an overarching vision of change. Jane Fonda's emphasis on the importance of making narratives of gender a central organizer for personal and societal transformation, Hedda Bolgar's insistence that psychoanalysts recognize the complex dialectic between unconscious dynamics and sociocultural realities in order not to conflate conflicts rooted in social inequalities with individual issues, and Sue Shapiro's understanding of the ambiguous role of individual therapy in situations of historical and social trauma such as the tsunami in Indonesia are all examples of fourth wave feminism in practice. The unfinished business of the ...
The genetically significant dose (GSD), per Caput mean bone marrow dose (CMD), leukemia significant dose (LSD) and malignancy significant dose (MSD) from medical diagnostic X-ray examinations in Japan were estimated based on a 1979 nationwide survey of randomly sampled hospitals and clinics. The population risk estimates were carried out using the resultant values of GSD, LSD and MSD. In the risk estimates, the significant factors, namely, the relative child expectancy, the leukemia significant factor and the malignancy significant factor, for patients were assumed to be same as those of general population. The risk factors used were 185 x 10"-"6 rad"-"1 for genetic risk of all generations, 20 x 10"-"6 rad"-"1 for fatal leukemia and 165 x 10"-"6 rad"-"1 for fatal malignant diseases, respectively. The resultant annual population doses per person were 15 mrad (0.15 mGy) for GSD, 107 mrad (1.07 mGy) for CMD, 86 mrad (0.86 mGy) for LSD and 43 mrad (0.43 mGy) for MSD, ...
Objective was to follow the cognitive and creative processes demonstrated by student research participants as they integrated a developing knowledge of ``big`` science, as practiced at LLNL, into a personal and idiosyncratic visual, graphical, or multimedia product. The participants, all non-scientists, involved in this process, attended a series of design classes, sponsored by LLNL at the Art Center College of Design in Pasadena CA. As a result of this study, we have become interested in the possibility of similar characteristics between scientists and artists. We have also become interested in the different processes that can be used to teach science to non-scientists, so that they are able to understand and portray scientific information.
Nasal cavity volume was studied in 69 healthy volunteers (from 8 to 23 years old) by MRI. The right and left nasal cavity areas were measured on horizontal images displayed directly on the MRI console. The nasal cavity volume was obtained by integrated volume calculation. The nasal cavity volume was positively correlated with age, body height and weight up to age 16. The body height and weight reached a plateau at 16 years, but the nasal cavity volume continued to increase. There was no significant difference in the volumes of the right and left cavities. (author).
Nasal cavity volume was studied in 69 healthy volunteers (from 8 to 23 years old) by MRI. The right and left nasal cavity areas were measured on horizontal images displayed directly on the MRI console. The nasal cavity volume was obtained by integrated volume calculation. The nasal cavity volume was positively correlated with age, body height and weight up to age 16. The body height and weight reached a plateau at 16 years, but the nasal cavity volume continued to increase. There was no significant difference in the volumes of the right and left cavities. (author).
The use of workstations, controllers or embedded systems and their applications have become much more relevant than previously. PC-based systems, a cooker programmer, applications of, for example, Prolog machines, Unix and Ada papers, Robotics and Automation are typical examples of this. The three keynote addresses of this symposium have as their subjects the most spectacular microcomputer fields and are presented by leading experts. The papers presented cover most of the traditional interests of Euromicro. Special emphasis is given to contributions on the use of workstations and personal computers, on RISC and GaAs and on transputers.
H.S.H. Prince Radu of Hohenzollern-Veringen, Special Representative of the Romanian Government for Integration, Co-operation and Sustainable Development, is seen here visiting Microcosm, CERN's on-site exhibition centre. Photo 01: H.S.H. Prince Radu of Hohenzollern-Veringen (right) with his personal adviser Cornel Comsa inside Microcosm's full-scale model of a six-metre section of the LHC. Photos 04-06: H.S.H. Prince Radu of Hohenzollern-Veringen with Emma Sanders from ETT Division.
The paper investigates the yield and the role of the computerized tomography in diagnosing abdominal gunshot wounds, with their rich and varied radiological signs and associated injuries, and subsequently used in the diagnosis. [Italian] Scopo del lavoro e' riportare l'esperienza personale nell'uso della tomografia computerizzata per riconoscere le lesioni da arma da fuoco dell'addome e nelle fasi successive dell'approfondimento diagnostico.
Purpose - The article shares insights from a program that was developed to address burnout, compassion fatigue and vicarious trauma. The program works from the premise that people and organizations thrive when they have shared values and common understandings. Design/methodology/approach - The approach draws together reflection at the organizational and person levels. Connecting business ethics and organizational analysis, improving understanding of the body's energy as well as inter-cultural understanding are all achievable while adopting the resilience development methods. Findings - The article concludes that reflective practice through the tools used on the program enhances understanding of the challenges faced by organizations and the individuals involved. It provides creative routes ...
Variation of CT units, in organs, before and after using contrast enhancing medium was reviewed and personal experience was presented. In the normal brain CT units was little changed by contrast enhancement (CE), whereas remarkable change was observed at lesions. No difference of CT units was observed between the normal liver and hepatomas. The normal kidney had higher CE effect than hypernephromas suggesting an increase of the sensitivity. CE was not found in cysts or necrosis. The changes of CT units in the cases of cerebral diseases are tabled with various contrast medium and scanners.
During the 1990s, a debate took place in Sweden concerning Conductive Education. Proponents of this method focused their critique on the role and methods of physiotherapists but this profession was not active in the debate. Instead, the medical profession came out as defenders of habilitation services and methods. Departing from sociology of the professions, our objective in this article is to analyze the physiotherapists' silence in relation to the profession's position and its relation to the medical profession. The analysis is based on data from interviews with members of habilitation teams and other key persons, and on documents. The relative silence of physiotherapists is found to be related to both interprofessional factors (the subordination under the medical profession paired with ...
Original pictures installed in the 1st and 2nd generation type central control panels (CCP) and new 'Awarable and Complex' pictures were made on personal computers and evaluated. A total 18 of actual plant operators (M=32.3, SD=10.5 years old) participated in the evaluation. The operators rated the new CRT pictures highly. The response times using the new CRT pictures were shorter than those by the original pictures. Both results suggested that the CRT picture design guidelines based on the operators' plant images were effective for improving their performance. (author)
The use of reversible pump/turbine sets in pumped storage has created a requirement for rapid reversibility. Softstart technology, based on static frequency converters (SFC) has evolved to such an extent that it is now the best choice for serving this purpose, both from a technical and from an economic point of view. The objective of our paper is to give the owners of pumped storage plants and those persons responsible for the selection, the operation or the maintenance of the electrical equipment the necessary insight into the SFC functions, features and all other application related aspects, to facilitate their decision making process. Case studies are included.
The single specimen unloading compliance technique has become the preferred method for evaluating J-integrals. It involves data acquisition and analysis using a computer. This paper describes in detail the development of a simple experimental system and related software that can be used in a laboratory equipped with a microcomputer and with access to a minicomputer. The effects of loading rate, test temperature, specimen geometry and material composition can be readily evaluated using this system. The results on a pressure vessel steel and an #alpha#-#beta# titanium alloy are discussed in Part II. (author).
The incidence of anogenital malignancies is greatly increased in patients who have received a renal transplant, but this has not been well studied in patients receiving maintenance dialysis. Our aim was to assess the incidence of these malignancies in patients on dialysis and compare these to transplanted patients. The age standardized incidence ratio (SIR) for anogenital malignancies was calculated by comparing the observed number of malignancies to the expected number. The expected number was calculated by multiplying the age specific incidence rates for each malignancy by the person years at risk in 5-year age cohorts. Of 15,820 patients in the Australia and New Zealand data base, 8,215 had received a renal transplant. A total of 39,750 person years at risk were contributed by patients who had received a renal transplant, while 29,276 person years at risk were contributed by dialysis patients who had not received a renal ...
According to ICRP 60 and European-Directive 96/29, Naturally Occurring Radioactive Materials (NORM) and Technical Enriched Naturally Occurring Radioactive Materials (TENORM) have to take the radiation protection of the general population as well as of workers into account. The German radiation protection regulations stress that particularly. In connection with these regulations, various measurement programs have been and still are performed to investigate the relevant exposure paths. One of these programs is the determination of the intake of natural occurring radionuclides of the uranium decay series in individuals of the public, in exposed regions and houses and also at NORM workplaces by excretion analysis. Excretion analysis surveillance is one of the common tools for internal dosimetry. Sources of primordial radionuclides could be the ingestion of foodstuff and water and the incorporation of (mostly airborne) pollution on work places. The main focus in this report is set upon the ...
Purpose: Antitumor activity of the dichloroplatinum(II)-histamine complexes labeled with I-125 or I-131 was investigated in a transplantable murine adenocarcinoma (MA) model. Methods: The tumor model was obtained in C3H/W female mice after subcutaneous inoculation of the tumor cells derived from the mice bearing a mammary tumor of spontaneous origin. Antitumor activities of the platinum-histamine complexes were investigated in three independent experiments, which differed in applied doses of preparations (PtCl{sub 2}Hist, PtCl{sub 2}[{sup 125}I]Hist, PtCl{sub 2}[{sup 131}I]Hist, PtCl{sub 2}Hist/PtCl{sub 2}[{sup 125}I]Hist and PtCl{sub 2}Hist/PtCl{sub 2}[{sup 131}I]Hist), treatment schedules as well as stages of the disease progress in the animals used. Experiment 1 included long-term, multidose treatment with low single doses (treatment duration 31-32 days; 8-10 doses of ca. 0.25{center_dot}MTD{sub Pt} each). Experiment 2 included short-term, multidose treatment with higher single ...
Measurement results of total interaction cross sections averaged by the spectrum of ultracold neutrons (UCN) within the rate range from 3.2 to 5.7 m/s at the temperatures of 80 and 300 K for the following gases: hydrogen, parahydrogen, helium-4, nitrogen, neon, argon, xenon are presented. The experiment has been conducted conducted in the facility for UCN extraction, mounted in the radial channel of the WWR-K reactor. Experimental dependences of UCN counting rate on pressure of the investigated gases in the chamber varying from 0 to 1.5x10/sup 3/ torr are presented graphically. The measured total cross sections mainly satisfactorily agree with calculations, divergences are observed only for hydrogen and xenon.
Time-resolved characterizations of electron beams using optical transition radiation (OTR) as a prompt conversion mechanism have recently been extended on the Los Alamos Free-electron Laser (FEL) facility 40-MeV linac. Two key timescales for rf-linac driven FELs are the micropulse (10 ps) and the macropulse (5 {mu}s to 1 ms). In the past we have used gated, intensified cameras to select a single or few micropulses (25 to 400 ns gate width) out of the pulse train to evaluate submacropulse effects. Recently, we have obtained some of the first measurements of micropulse bunch length (7 to 10 ps) and submacropulse spatial position and profile using OTR and a Hamamatsu streak camera. Additionally, micropulse elongation effects and head-to-tail transverse kicks are reported as a function of charge.
Time-resolved characterizations of electron beams using optical transition radiation (OTR) as a prompt conversion mechanism have recently been extended on the Los Alamos Free-electron Laser (FEL) facility 40-MeV linac. Two key timescales for rf-linac driven FELs are the micropulse (10 ps) and the macropulse (5 {mu}s to 1 ms). In the past we have used gated, intensified cameras to select a single or few micropulses (25 to 400 ns gate width) out of the pulse train to evaluate submacropulse effects. Recently, we have obtained some of the first measurements of micropulse bunch length (7 to 10 ps) and submacropulse spatial position and profile using OTR and a Hamamatsu streak camera. Additionally, micropulse elongation effects and head-to-tail transverse kicks are reported as a function of charge.
A high-density gas jet supersonic nozzle is reported in this paper. The jitter and actuation time of the nozzle is determined by the pin discharge and laser spark radiation respectively. The jitter time of the nozzle is within 10 ?s with the backing pressure as high as 25 bar. With a nanosecond laser pulse focused on the gas jet about 1 mm below the nozzle, the actuation time is calculated to be about 15 ms by detecting the laser produced spark radiation, which reveals the existence of the gas jet and the relative gas density evolving with time. Consequently the gas density is estimated to be well above 1019 cm-3, compared with theoretical simulations from the nozzle parameters.
The spatial distribution of argon clusters in gas jet is tested using the Rayleigh scattering method. A pulsed laser is used to acquire the whole evolution of the cluster inside one event. The measured results at a fixed axial position show that the argon clusters grow in less than one millisecond after the nozzle is opened and the cluster size keeps constant during the whole open period of 20 ms. Further results show that the scattering signal along the radial direction is almost Gaussian-distributed and the full width half maximum (FWHM) increases almost linearly when the distance from nozzle increases. The scattering signal along the axial direction is Landau-distributed and the area near the nozzle is most effective for laser cluster interaction. (authors)
Four-enzyme section of the shikimate pathway (Aro B, D, E, and K) of Streptococcus pneumoniae has been studied. Kinetic properties of the individual enzymes and three- and four-enzyme linked reactions have been characterized in vitro. On the basis of the data measured in spectrophotometric and LC-MS experiments, kinetic mechanisms of the enzymes have been suggested and all kinetic parameters have been identified. Kinetic models for these three- and four-enzyme sections of the shikimate pathway have been constructed and validated. The model of the four-enzyme section of shikimate pathway has been employed to design an inhibition-sensitive reconstituted pathway for a high-throughput screening effort on the shikimate pathway. It was demonstrated that using the model it was possible to optimize this reconstituted pathway in such a way to provide equal sensitivity of the enzymes to inhibition. PMID:16921527
Cadmium telluride single crystals were grown heavily doped with chloride by the THM method. The resulting crystals were n-type with free carrier concentrations of the order of 10('12)/cm at room temperature. Hall effect studies revealed room temperature mobilities between 30 and 350 cm('2)/v-sec and resistivites between 2 x 10('3) and 10('4) ohm-cm. Studies were made of the gamma and alpha counting characteristics of these crystals with metal, metal-semiconductor, and metal-insulator electrodes. It was found that the MIS and MSS structures resulted in significant improvement over the MS structures in counting, signal-to-noise and energy resolution.
In April and May of 1999 the Berkeley Gas-filled Separator was used to search for the production and decay of element 118 from the {sup 86}Kr + {sup 208}Pb reaction, according to Smolanczuk's predictions of relatively large production rates. Three decay chains, each consisting of an implanted heavy ion, followed by a rapid (ms) succession of high-energy (>10 MeV) alpha-particle decays were detected. These chains are consistent with the production and decay of element 118 with mass number 293. These results a) show experimental evidence for the existence of shell-stabilized superheavy elements, b) provide experimental values for refinement of nuclear mass models in the superheavy element region, and, most importantly, c) present a new' reaction pathway for the production of superheavy elements. (author)
Purpose: The aim of this study was to test the feasibility of iliac artery stent placement under MR guidance with real-time MR radial scanning in an animal model. Materials and methods: The experiments were performed on three pigs in a 1.5 T scanner. Radial scanning with a gradient echo technique (T{sub R} 8.4 ms, T{sub E} 3.6 ms, flip angle 10 ) was used. A dedicated backprojector performed the reconstruction of the raw data in real-time. The resulting MR-images were displayed on LCD screens beside the magnet. The sliding window reconstruction technique allowed image acquistion at a frame rate of 16 images per second. MR-compatible self-expanding stents with a diameter of 8 mm and a length of 3 cm were placed into the left iliac artery. Their positions were verified by digital subtraction angiography (DSA) and compared to MRI. Results: All stents were successfully placed. Stent positions as monitored by real-time MR were identical to those ...
Spatial Fluorescence Cross Correlation Spectroscopy is a rarely investigated version of Fluorescence Correlation Spectroscopy, in which the fluorescence signals from differ-ent observation volumes are cross-correlated. In the reported experiments, two observation volumes, typically shifted by a few $\\mu$m, are produced, with a Spatial Light Modulator and two adjustable pinholes. We illustrated the feasibility and potentiality of this technique by: i) measuring molecular flows, in the range 0.2 - 1.5 $\\mu$m/ms, of solutions seeded with fluorescent nanobeads or rhodamine molecules (simulating active transport phenomenons); ii) investigating the perme-ability of phospholipidic membrane of Giant Unilamellar Vesicles versus hydrophilic or hydrophobic molecules (in that case the laser spots were set on both sides of the mem-brane). Theoretical descriptions are proposed together with a discussion about FCS based, alternative methods.
In this Letter, we demonstrate the application of time-resolved fluorescence anisotropy measurements to detect solution state hybridization of streptavidin conjugate (CdSe)ZnS quantum dots (QD). The study was performed on samples containing 10nM QD incubated with 800nM DNA. We show that the rotational correlation time of QD-DNA constructs increases significantly upon hybridization with values of 330ns (QD-ssDNA) and 1.3ms (QD-dsDNA), corresponding to a diameter of 14nm and 23nm respectively. The present study opens a new modality for hybridization detection using quantum dots.
Deep brain stimulation (DBS) has been used for relieving chronic pain in patients that have been through other existing options. The septum has been one of the targets for such treatment. The purpose of this study was to determine the inhibitory effect of electrical stimulation in the medial septum diagonal band of broca (MSDB) on neuronal activity in the spinal cord of rats anesthetized with sodium pentobarbital. While unilaterally stimulating the MSDB, wide dynamic range neurons in the lumbar region of the spinal cord were recorded in response to graded mechanical stimulation of the hind paws (brush, pressure, and pinch). Stimulation was at 1, 5, 10, and 20V, at 100Hz, and 0.1ms duration. Significant bilateral reduction was observed in response to pressure (ipsilaterally: 0.90+/-0.05, 0....
Purpose: An animal model is used to investigate whether MR angiography combined with super-paramagnetic particles of iron oxide (SPIO) is suitable for detecting thromboses. Methods: 42 rats in groups of 7 each were examined on days 1, 3, 5, 7, 9 and 11, respectively, after mechanical/chemical thrombus induction in a 1.5 Tesla magnet with a FISP sequence (TR/TE/FA 50 ms/6 ms/40 ). Imaging was performed before and up to 90 minutes after intravenous injection of 30 {mu}mol FE/kg BW of the experimental SPIO (hydrodynamic diameter, 34{+-}17 nm LLS; R1 and R2 relaxivity at 0.47 T, 31 and 57 L/(mmol*s)). MIP reconstructions of MR angiographies were submitted to consensus assessment by two examiners using histology as the gold standard. Results: The image quality of MIP reconstructions was rated as good in 38 of 42 cases. With regard to thrombotic vessel occlusion, MR angiography coincided with histology in 17 of 42 cases and differed in 25, lumen ...
The half-lives of "4"1Ar, "8"0"mBr, "9"4"mNb, "1"0"1Mo, "1"0"1Tc, "1"0"9Pd, "1"0"9"mPd, "1"2"2Sb, "1"2"2"mSb, "1"2"3"mSn, "1"5"2"mEu and "2"3"9Np have been measured more accurately compared to previous measurements. All of these half-lives and 39 others published earlier will be cited by M.S. Antony in the forthcoming project 'Chart of the nuclides - Strasbourg, 1990' due to appear early 1991. (author) 34 refs.; 4 figs.; 2 tabs.
During the last two years, the performance of the Penning trap mass spectrometer ISOLTRAP at ISOLDE/CERN (Geneva) has been considerably enhanced. Many technical improvements have been completed (i) to access nuclides that are produced in minute quantities of only 100 ions s/sup -1/, (ii) to increase the relative mass accuracy to ms. The major steps are presented, in particular the recent implementation of a magnetron phase locking mechanism which results in a significant reduction of the duration of ISOLTRAP's cyclotron measurements. (20 refs).
A method for range-resolved gas sensing using path-integrated optical systems is presented. The method involves dividing an absorption path into several measurement segments and extracting the gas concentration in each segment from two path-integrated measurements. We implemented the method with tunable lasers (a 1389-nm VCSEL and a 10.9-?m pulsed quantum cascade laser) and a group of retro reflectors (RRs) distributed along absorption paths. Using a rotating mirror with the VCSEL configuration, we could scan a group of seven tape RRs spaced by 10?cm in ??9?ms to extract an H2O concentration profile. Reduced H2O concentrations were recorded in the segments purged with dry air. Hollow corner cube RRs were used in the quantum cascade laser configuration at distances up to 1.1?km from the las...
The noncrystalline compounds MoS_3, WS_3 and MoSe_3 were studied by X-ray diffraction. From the diffuse intensities radial distribution functions were computed and interpreted in terms of pair distribution functions. The substances are built up by microcrystallites which contain three metal atoms and are bridged statistically to each another. The shortest metal chalcogen distances d(MoS) approximately d(WS) = 2.40 +- 0.05 A and d(MoSe) = 2.50 +- 0.05 A are significantly longer than in MS- or MSe compounds with a d"0 configuration of the metal respectively and metal-metal distances within the microcrystallites are less than 3 A. (author).
A back-propagation neural network technique is used at JET to extract plasma parameters like ion temperature, rotation velocities or spectral line intensities from charge exchange (CX) spectra. It is shown that in the case of the C VI CX spectra, neural networks can give a good estimation (better than +-20% accuracy) for the main plasma parameters (Ti, V{sub rot}). Since the neural network approach involves no iterations or initial guesses the speed with which a spectrum is processed is so high (0.2 ms/spectrum) that real time analysis will be achieved in the near future. 4 refs., 8 figs.
The precedence effect (PE) is thought to be beneficial for proper localization and perception of sounds. The majority of recent physiological studies focus on the neural discharges correlated with PE in the inferior colliculus (IC). Pentobarbital anesthesia is widely used in physiological studies. However, little is known of the effect of pentobarbital on the discharge of neurons in PE. Neuronal responses in the IC from 23 male SD rats were recorded by standard extracellular recording techniques following presentation of 4ms white noise bursts, presented from either or both of two loud speakers, at different interstimulus delays (ISDs). The neural responses were recorded for off-line analysis before or after intraperitoneal administration of pentobarbital at a loading or maintenance dose. ...
Two new triterpene glycosides, patagonicosides B and C (2 and 3, resp.), together with the known patagonicoside A (1), have been isolated from the EtOH extract of the sea cucumber Psolus patagonicus. The structures of the new compounds were established on the basis of extensive NMR spectroscopic analysis ((1)H- and (13)C-NMR, (1)H,(1)H-COSY, HMBC, HSQC, TOCSY, and NOESY), HR-ESI-MS data, and chemical transformations. Compounds 1-3 and their desulfated analogs showed antifungal activities against the phytopathogenic fungus Cladosporium cladosporoides in a dose-dependent fashion. PMID:21404430
The roughness length at air-sea interface during free convection (Z0fc) is mainly related to the convective velocity (w) rather than the friction velocity (u). The parameterization of Z0fc with (w)2/g as proposed by Abdella and D'Alessio (2003) is evaluated. It is shown that the field measurements at MM Lab, Tarapur Maharashtra Site (TMS) coastal site using Metek GmbH, Ultra sonic anemometers are consistent with the proposed formula. In order to avoid self-correlation by using u, a new parameterization of w with ?u and ?v and gustiness parameter as given by Fairall et al. (1996) is used. The mean values of w and Z0fc estimated using new parameterization were observed to be 0.97 m/s and 2.3E-4 m respectively for the year 2009 at TMS. (author)
Nanocrystalline MnFe"2O"4 ferrite was prepared by using autocombustion technique (flash). The microstructure and magnetic properties are studied. The results of XRD and TEM clarified that, this ferrite is nanosized with particle size (39 nm). Magnetic measurements showed a ferromagnetic behavior with T"C = 613 K, the saturation magnetization M"s = 13.71 emu/g, remanent magnetization M"r = 0.1694 emu/g and, coercivity H"c = 25.6 Oe. Natural material, egg white used as an aqueous medium to extend prepare nanoparticles better than other chemical interesting materials.
Monte Carlo neutron transport methods can be used to verify the applicability of point kinetics for safety analysis of nuclear reactors. KENO-NR was used to obtain the transfer function of the Advanced Neutron Source reactor and the time delay between the core power production and the external detectors, a parameter of interest to the safety systems design. The good agreement between the Monte Carlo generated transfer function and the point kinetics transfer function validates that the uncommon ANS geometry does not preclude the use of point kinetics in the frequency range that was investigated. Various features of the power spectral densities also demonstrated the applicability of point kinetics. The time delay was obtained from the cross-power spectral density (CPSD) and is {approximately}15 ms. These analyses show that frequency analysis can be used experimentally to investigate the validity of the use of point kinetics models in critical experiments or zero ...
The present invention relates generally to an apparatus and method for separating high molecular weight molecules from low molecular weight molecules. More specifically, the invention relates to the use of microdialysis for removal of the salt (low molecular weight molecules) from a nucleotide sample (high molecular weight molecules) for ESI-MS analysis. The dialysis or separation performance of the present invention is improved by (1) increasing dialysis temperature thereby increasing desalting efficiency and improving spectrum quality; (2) adding piperidine and imidazole to the dialysis buffer solution and reducing charge states and further increasing detection sensitivity for DNA; (3) using low concentrations of dialysis buffer and shifting the DNA negative ions to higher charge states, producing a nearly 10-fold increase in detection sensitivity and a slightly decreased desalting efficiency, or (4) any combination of (1), (2), and (3).
Using electrochemical techniques of pH-metry and conductimetry, the choice of a suitable complexing reagent was made amongst ethylene glycol, propylene glycol, dextrose and mannitol for cost-effective separation of isotopes of boron by ion exchange chromatography. Quantitative relationships between pH and concentration; pK_a and concentration of each of these complexing reagents were determined by least square polynomial curve fitting and an attempt was made to determine the formation constants of mannitol-borate complex. The results of experiments carried out for selection; regeneration of a resin; separation factor determinations using batch as well as column techniques and monitoring of band movements using these electrochemical techniques are discussed. (author).
A set of 35 uranium ore and 10 yellow cake samples, collected worldwide from different mines and production sites, were analyzed for their impurity spectrum by ICP-MS. Pattern recognition techniques such as cluster analysis were applied to the data set in order to characterize samples with relation to their geographical origin. The results obtained show a clear relationship between samples taken from the same geological origin and constitute a satisfactory fingerprint for establishing the origin of the material. In addition to the impurity data, data on the isotopic composition of radiogenic lead is used to resolve ambiguity when impurity cluster analysis fails to deliver unambiguous origin data. (author)
Magnetic pulse welding is a solid state impact welding process, similar to explosive welding, which produces metallurgical bond by oblique high-speed impact between two metal bodies. This violent impact removes the metal surface oxide layers and then joins the two atomic level clean metal surfaces together by the incidental compression pressure. The impact velocity is at 200?400?m/s and the being welded metal surface undergoes severe plastic deformation with strain rate in the order of 106?107?s?1. The ultrafine-grained structure was observed on the welded interface. This article studied two types of similar material lap joint interfaces and the base metals were aluminum alloy 6061 and copper alloy 110. Nano-indentation testing shows that the welded interfaces have significantly greater ha...
This paper considers the physical and mechanical properties of rocks (volumetric density, angle of repose, lump size, abrasive strength, etc.), and their influence on choice of belt conveyors for overburden haulage. Technological parameters (length and output of benches, coefficient of utilization and reliability of equipment, investment cost, etc.) are also considered. Data are given on the capacity and length of conveyors widely used in coal surface mining (width up to 3,000 mm, speed up to 6 m/s and capacity 24,000-35,000 t/h at lengths of 1,400-3,000 m). (12 refs.) (In Serbo-Croat)
In this work, chromatographic separation of niacin and niacinamide using pure water as the sole component in the mobile phase has been investigated. The separation and analysis of niacinamide have been optimized using three columns at different temperatures and various flow rates. Our results clearly demonstrate that separation and analysis of niacinamide from skincare products can be achieved using pure water as the eluent at 60^oC on a Waters XTerra MS C18 column, a Waters XBridge C18 column, or at 80^oC on a Hamilton PRP-1 column. The separation efficiency, quantification quality, and analysis time of this new method are at least comparable with those of the traditional HPLC methods. Compared with traditional HPLC, the major advantage of this newly developed green chromatography techniq...
Results of calculational investigations into circulation of water and steam-and-water mixture in the PGV-1000 steam generator heat exchanger bundle used at NPPs with the WWER-1000 reactors, are considered. Model of water circulation in horizontal steam generator with submerged heating surface under conditions of steam generation irregularity along the heat transfer tubes is made. On the basis of the obtained data the assumption is made about water essential overflows from the hot collector zone into the cold one. Overflow rate over the upper line of the heat transfer tubes may constitute 0.7 m/s. The conclusion is made about the necessity to set up the vertical barrier which divides hot and cold sections of heat transfer tubes and helps to avoid water transverse overflows.
A novel heteropolyanion-based ionic hybrid was prepared by combining the divalent ionic liquid (IL) cation of 1,1'-(butane-1,4-diyl)-bis(3-methylimidazolium) with the Keggin-structured V-containing heteropolyanion, and characterized by ^1H NMR, FT-IR, ESI-MS, XRD, SEM, TG, BET surface area, melting point, and elemental analysis. Its catalytic activity was evaluated in the hydroxylation of benzene with aqueous H2O2, including the testing of the influence of organic cations, catalytic reusability and optimization of reaction conditions. This hybrid is characterized to be semi-amorphous nanoparticles with a IL-like composition. The hybrid catalyst leads to the liquid-solid biphasic reaction system for hydroxylation of benzene with H2O2, presenting such advantages as high catalytic activity, c...
This study was conducted to investigate the antibacterial effect of BSAP-254 on Bacillus cereus with the induced stress proteins. The BSAP-254 is an antimicrobial peptide isolated from soybean-fermenting bacteria, Bacillus subtilis SC-8. It had a narrow spectrum of activity against B. cereus group. The growth inhibitory effect of BSAP-254 (50??g/mL) reduced the population of B. cereus from >108 to 104 colony-forming units per milliliter within 30?min. In B. cereus exposed to BSAP-254, 14 intracellular proteins were differentially expressed as determined by 2-DE coupled with MS. Of the differentially expressed proteins identified, the stress protein GroEL, which is heat shock protein, was induced in B. cereus exposed to antibacterial peptide.
Time-resolved characterizations of electron beams using optical transition radiation (OTR) as a prompt conversion mechanism have recently been extended on the Los Alamos Free-electron Laser (FEL) facility 40-MeV linac. Two key timescales for rf-linac driven FELs are the micropulse (10 ps) and the macropulse (5 [mu]s to 1 ms). In the past we have used gated, intensified cameras to select a single or few micropulses (25 to 400 ns gate width) out of the pulse train to evaluate submacropulse effects. Recently, we have obtained some of the first measurements of micropulse bunch length (7 to 10 ps) and submacropulse spatialposition and profile using OTR and a Hamamatsu streak camera. Additionally, micropulse elongation effects and head-to-tail transverse kick effects are reported as a function of charge.
Time-resolved characterizations of electron beams using optical transition radiation (OTR) as a prompt conversion mechanism have recently been extended on the Los Alamos Free-electron Laser (FEL) facility 40-MeV linac. Two key timescales for rf-linac driven FELs are the micropulse (10 ps) and the macropulse (5 {mu}s to 1 ms). In the past we have used gated, intensified cameras to select a single or few micropulses (25 to 400 ns gate width) out of the pulse train to evaluate submacropulse effects. Recently, we have obtained some of the first measurements of micropulse bunch length (7 to 10 ps) and submacropulse spatialposition and profile using OTR and a Hamamatsu streak camera. Additionally, micropulse elongation effects and head-to-tail transverse kick effects are reported as a function of charge.
The leaf extract from the plant Piliostigma reticulatum was found to exhibit antimicrobial activity against some bacteria and fungi such as Staphylococcus aureus (NCTC 6571), Escherichia coli (NCTC 10418), Bacillus subtilis (NCTC 8236), Proteus vulgaris (NCTC 4175), Aspergillus niger (ATCC 10578) and Candida albicans (ATCC 10231). Upon investigation of the chemical constituents present in the leaf extract, a total of seven compounds were isolated and their structures were unambiguously established by spectroscopic methods including HR-MS and NMR spectrometry. Four of the isolated compounds were novel, namely 6-C-methyl-2-p-hydroxyphenyloxychromonol (piliostigmol), 1, 6,8-di-C-methylquercetin-3,3prime,7-trimethyl ether, 2, 6,8-di-C-methylquercetin-3,3prime-dimethyl ether, 3 and 3prime,6,8,-...
Flame propagating through zirconium particle cloud in a small-scale vertical rectangle chamber was investigated experimentally. In the experiments, the zirconium quoted 99% purity was used and the diameter of particles was distributed 1?22 ?m. The zirconium dust was dispersed into the chamber by air flow and ignited by an electrode spark. A high-speed video camera was used to record the images of the propagating flame. Micro-thermocouples, schlieren optical system and microscopic lens were used to obtain temperature profiles and flame structure, respectively. Based on the experimental results, flame propagation characteristics and flame structure of zirconium particle cloud were analyzed. The propagation velocity of the flame is quite slow in the initial 14 ms and then accelerates to maxim...
Extraction of 25 L fermentation broth of the newly isolated Streptomyces sp. strain TN58 and various separation and purification steps led to the isolation of five bioactive metabolites, namely brevianamide F (C1), reported from a streptomycete for the first time, N?-acetyltryptamine (C2), thiazolidomycin (C3), and two rhamnopyranosides (C4 and C5). These two rhamnopyranosides were produced directly, without precursor addition. The chemical structure of these five active compounds was established on the basis of 1H, 13C/APT and 2D NMR spectra, ESI and EI-MS data, and by comparison with data from the literature. According to the biological studies, we show in this work that the compounds C1, C2, C4 and C5 possess antimicrobial activities.
Fires and explosions have been identified as major potential hazards for Oil and Gas Floating Production Storage Offloading (FPSO) installations and pose risk to personnel, assets, and the environment. Current fire and explosion assessment (FEA) tools require physical effect modeling software and follows standards from API, ISO, and engineering practices. However, the tools are not specific to any particular system such as an FPSO, and do not provide comprehensive guidance for safety engineers to perform FEA. This paper discusses the development of a screening and comparison tool for FEA on FPSOs and the incorporation of an expert system into the tool. The results are computerized using MS Excel/VBA to provide a structured and comprehensive assessment on each equipment and module handling ...
This paper introduces a parallel measurement approach for fast infrared-based human temperature screening suitable for use in a large public area. Our key idea is based on the combination of simple image processing algorithms, infrared technology, and human flow management. With this multidisciplinary concept, we arrange as many people as possible in a two-dimensional space in front of a thermal imaging camera and then highlight all human facial areas through simple image filtering, image morphological, and particle analysis processes. In this way, an individual's face in live thermal image can be located and the maximum facial skin temperature can be monitored and displayed. Our experiment shows a measured 1ms processing time in highlighting all human face areas. With a thermal imaging ca...
Mixed convection heat transfer from longitudinal fins inside a horizontal channel has been investigated for a wide range of modified Rayleigh numbers and different fin heights and spacings. An experimental parametric study was made to investigate effects of fin spacing, fin height and magnitude of heat flux on mixed convection heat transfer from rectangular fin arrays heated from below in a horizontal channel. The optimum fin spacing to obtain maximum heat transfer has also been investigated. During the experiments constant heat flux boundary condition was realized and air was used as the working fluid. The velocity of fluid entering channel was kept nearly constant (0.15win0.16m/s) using a flow rate control valve so that Reynolds number was always about Re=1500. Experiments were conducted...
Solid particle erosion (SPE) testing was made on Sandvik CRC 262 with different heat treatments and on the steels Type 321 and 15Mo3. The Studsvik Erofuge, a centrifugal erosion tester, was used and the testing was performed in air at room temperature. Alumina and olivine sand particles were used at a particle velocity of 60 m/s and at impingement angles of 60 degrees and 90 degrees. Differences in erosion resistance were obtained for CRC 262 depending on the heat treatment. Olivine sand resulted in lower erosion of CRC 262 than when using alumina. The particle type dependence is low for the other materials, Tp 321 and 15Mo3. CRC 262 has a slightly higher erosion resistance than Tp 321 and 15Mo3 and the differences are most pronounced when using olivine sand
We consider the effect of distributed delays in neural feedback systems. The avian optic tectum is reciprocally connected with the nucleus isthmi. Extracellular stimulation combined with intracellular recordings reveal a range of signal delays from 4 to 9 ms between isthmotectal elements. This observation together with prior mathematical analysis concerning the influence of a delay distribution on system dynamics raises the question whether a broad delay distribution can impact the dynamics of neural feedback loops. For a system of reciprocally connected model neurons, we found that distributed delays enhance system stability in the following sense. With increased distribution of delays, the system converges faster to a fixed point and converges slower toward a limit cycle. Further, the introduction of distributed delays leads to an increased range of the average delay value for which the system's equilibrium point is stable. The enhancement of stability with ...
Korean ginseng (Panax ginseng C.A. Meyer) contains several types of saponins and ginsenosides, which are usually considered the major active components of ginseng. The types and quantities of saponins found in ginseng may differ depending on the region of cultivation. As a result, ginsengs produced in different areas of Korea have been unintentionally mislabeled and/or confused by Korean herbal markets owing to their complicated plant sources. Another concern is that 4- and 6-year-old ginseng roots, traditionally prescribed for different medicinal purposes, can vary in total saponin contents. Therefore, it is necessary to establish a reliable method for distinguishing different cultivation regions and ages of ginseng roots. A rapid resolution liquid chromatography-quadruple time of flight ...
We report on severe accident scenarios consequences evaluation in connection to the applied emergency countermeasures and use of the PC COSYMA code. We present some of the results for the reactor core melt accident assumed to happen at the 632 MWE PWR Krsko Nuclear Power Plant in Slovenia. The efficiency of several potential countermeasures in limiting the late health effects was studied. Regarding the source term, the majority of release parameters are as specified for category 2 in the German Risk Study. Site specific data were used. As the outside (meteorologic) conditions during the potential accident onset can be very different, the study limited to the deterministic runs, assuming the wind direction upstream the Sava river into the WNW direction, wind speed of 5 ms -1 and the C Pasquill stability category. The population distribution file was formed from the NEK-FSAR data for the 1991. (author)
For investigating carryover of some organophosphorus pesticide residues in the cereal food chain from grain to consumer, a study was set up on wheat bran, flour and cookies, with and without bran. Special emphasis was given to malathion and chlorpyrifos-methyl residues in cookies for better protection of consumers. Pesticide-free wheat was placed in a small-scale model of a commercial storage vessel and treated with these pesticides. The residue levels of insecticides were determined in wheat, as well as in bran, flour and cookies produced from stored wheat at various time intervals during storage. A multiresidue analysis was performed using GC-NPD and GC-MS. Malathion and chlorpyrifos-methyl residue levels were higher than the maximum residue limits (MRLs) in wheat after 240days of storag...
The decomposition of three ?-lactam antibiotics (amoxicillin, oxacillin and ampicillin) in aqueous solution was investigated using a dielectric barrier discharge (DBD) in coaxial configuration. Solutions of concentration 100 mg/L were made to flow as a film over the surface of the inner electrode of the plasma reactor, so the discharge was generated at the gas-liquid interface. The electrical discharge was operated in pulsed regime, at room temperature and atmospheric pressure, in oxygen. Amoxicillin was degraded after 10 min plasma treatment, while the other two antibiotics required about 30 min for decomposition. The evolution of the degradation process was continuously followed using liquid chromatography-mass spectrometry (LC-MS), total organic carbon (TOC) and chemical oxygen demand (COD) analyses. PMID:21514950
The use of chemically selective laser ionization combined with beta-delayed neutron counting at ISOLDE has permitted identification and half-life measurements for {sup 61}Mn up through {sup 69}Mn. The 14(4)-ms half life for {sup 69}Mn is one of the shortest determined for any nuclide beyond the sd shell. Gamma-ray singles and coincidence spectra have been determined for the decays of {sup 64,66}Mn to levels of {sup 64,66}Fe, revealing strong deformation and vanishing of the N=40 subshell in the Fe isotopes. {copyright} {ital 1998 American Institute of Physics.}
The use of chemically selective laser ionization combined with beta-delayed neutron counting at ISOLDE has permitted identification and half-life measurements for "6"1Mn up through "6"9Mn. The 14(4)-ms half life for "6"9Mn is one of the shortest determined for any nuclide beyond the sd shell. Gamma-ray singles and coincidence spectra have been determined for the decays of "6"4","6"6Mn to levels of "6"4","6"6Fe, revealing strong deformation and vanishing of the N=40 subshell in the Fe isotopes.
Salt stress elicits betaine accumulation to high levels in species from several diverse dicot families (Chenopodiaceae, Amaranthaceae, Convolvulaceae, Solanaceae, and Asteraceae). FAM-MS studies with deuterated precursors showed that species from all these families synthesize betaine from choline. Enzyme assays and immunotitration data showed that all accumulating species contained betaine aldehyde dehydrogenase (BADH) enzyme activity recognized by antibodies raised against purified BADH isolated from Spinacia oleracea. Immunoblotting indicated that the BADH monomer was in all cases of Mr {approx} 63,000. The similarity of BADH in the different species is consistent with a single evolutionary origin for the betaine pathway. This was supported by the presence in immunoblots of a cross-reacting band at Mr {approx} 63,000 in Magnolia x Soulangiana, a primitive angiosperm.
Recently, foods are often exposed to radiation under packed states with various wrapping materials. In this study, the effects of #gamma#-ray radiation were investigated on the additives in wrapping materials on the market. 10 - 50 kGy #gamma# radiation was irradiated to samples under sealed condition in a glass-ware. Polyethylene bag and wrapping film, polypropylene wrapping film, cup and sheet, and polystyrene cup were used as samples. And the additives in these materials were analyzed by GC/MS to evaluate the radiation effects on them. The irradiation was found to induce rapid degradation of antioxidants, especially, Irgafos 168. Some fatty acid amides used as a lubricant and a plasticizer, DBP were also reduced, but not aliphatic hydrocarbons. However, all polystyrene products used in this study included no additives. The contents of styrene dimer and trimer in those wrapping materials were not changed by #gamma#-irradiation. (M.N.)
Purpose To study the chemical modifications induced upon irradiation of solid human insulin at radiosterilization doses and investigate the influence of the absorbed dose on radiolysis. Materials and Methods Volatile radiolytic products were monitored by gas chromatography coupled with mass spectrometry (GC-MS) and non-volatile products by two different high performance liquid chromatography (HPLC) methods: the formation of higher molecular weight proteins was assessed by size exclusion liquid chromatography whereas assays for related compounds and chemical potency tests were carried out using reverse-phase HPLC-UV. Conformational changes were investigated by measurements of circular dichroism. Results After gamma irradiation at 10?kGy, the recovery of insulin was 96.8%; higher molecular w...
This paper describes the design, fabrication and application of a micro-fabricated salinity sensor system. The theoretical electrochemical behaviour is described using electrical equivalent diagrams and simple scaling properties are investigated analytically and numerically using finite element method (FEM). The chip design and fabrication is described and measurement results of two different electrode designs are presented. The 4mm Formula Not Shown 4mm multi-sensor allows for salinity determination with an accuracy of Formula Not Shown 0.5psu through determination of the electrical conductivity, temperature and pressure with accuracies of Formula Not Shown 0.6mS, Formula Not Shown 0.065 Formula Not Shown C and Formula Not Shown 0.05bar, respectively.
A series of desilicated ZSM-5 catalysts previously shown to have improved catalytic performance in the MTG (methanol-to-gasoline) reaction [M. Bjorgen, F. Joensen, M.S. Holm, U. Olsbye, K.-P. Lillerud, S. Svelle, Appl. Catal. A 345 (2008) 43] was subjected to thorough examination using FTIR. Clearly, defects represented by internal Si-OH sites are removed upon NaOH treatment. In a parallel manner, free Si-OH sites increase in concentration and the results point to a selective mechanism for formation of mesopores as the framework dissolution preferentially takes place at defective sites in the crystallites. The acid properties of the desilicated materials were investigated by applying CO and collidine (2,4,6-trimethylpyridine) as molecular probes. Monitoring the induced frequency shifts upo...
Charge carrier profiles are measured for boron implanted into silicon (E = 30 keV, dose range 5 x 10"1"5 to 2 x 10"1"6 B/cm"2) after rapid isothermal annealing using halogen lamps. Maximum temperatures between 1000 and 1300 "0C and holding times at T/sub max/ of 5 and 20 s are used for the annealing treatment. In a few additional experiments flash lamp annealing at 1350 "0C (pulse duration 20 ms) is investigated. By comparison of the experimental profiles with computer simulations using the SUPREM II program transient enhanced diffusion of boron could be detected in all investigated cases. Maximum charge carrier concentrations above the equilibrium solubility of boron are observed and are discussed. (author).
The availability of hourly air relative humidity (HARH) data is a key requirement for the estimation of epidemic dynamics of plant fungal pathogens, in particular for the simulation of both the germination of the spores and the infection process. Most of the existing epidemic forecasting models require these data as input directly or indirectly, in the latter case for the estimation of leaf wetness duration. In many cases, HARH must be generated because it is not available in historical series and when there is the need to simulate epidemics either on a wide scale or with different climate scenarios. Thirteen modelling solutions (MS) for the generation of this variable were evaluated, with different input requirements and alternative approaches, on a large dataset including several sites a...
An efficient micropropagation protocol was established for Cryptocoryne wendtii and Cryptocoryne becketti using shoot tips explants. Multiple shoots were induced from shoot tip explants of both species cultured on agar-gelled as well as liquid MS medium supplemented with 0.5?mg/L BA and 0.2?mg/L IBA (proliferation medium). The multiple shoots of both the species formed on agar-gelled as well as liquid medium were vigorously growing with well-developed roots and leaves after 4?weeks of culture. Highest number of multiple shoots was obtained from shoot tip explants of both the species cultured in liquid proliferation medium after 4?weeks of culture. The shoot tip explants of C. wendtii and C. becketti, that were cultured in liquid proliferation medium (2?weeks) followed by culturing on agar-...
Fermented sausages were produced with 25%, 50%, 75% or 100% of their pork back fat content replaced by amorphous cellulose gel. The sausage production was monitored with physical, chemical and microbiological analyses. The final products were submitted to a consumer study, and the volatile compounds of the final products were extracted by solid-phase microextraction and analyzed by GC/MS. The reformulated fermented sausages had significant reductions in fat and cholesterol, and the volatile compounds derived from lipid oxidation were also reduced in the final products. These results suggest that the substitution of up to 50% of the pork back fat content by amorphous cellulose gel can be accomplished without a loss of product quality, enabling the production of fermented sausages with the l...
A number of aerobic species capable of decolorizing some of the dyes in a textile mill effluent were isolated. One of the isolates was able to decolorize Terasil black dye under aerobic conditions in the presence of an exogenous carbon source after 5 days. Glucose or starch (%1 ea) are essential for decolorization but the process proceeds faster in the presence of 0.5% yeast extract. Results of the BOD5 show that the untreated effluent samples have a low BOD value, whereas treated samples show an initial increase in BOD up to 15 days followed by a decrease after 20 days. FT-IR and GC-MS data also reveal that the initial components in the untreated effluent disappear after 20 days of treatment, confirming biodegradation of the dye. Phytotoxicity tests on the untreated effluent samples using...
The six-axes industrial robot MANUTEC r15 UW was modified to work underwater and successfully tested down to the simulated water depth of 1100 m. Next step in the program was to use this robot as a handling tool for inspection tasks at the welding seam of an underwater structure conducted with CCD-cameras and distance sensors. This was also to demonstrate the possibility to assist and later on to replace divers from this work. Additional research was focussed on the stiffness and rigidity of the robot during the precise guiding of tools and workpieces under current water conditions up to a flow velocity of 1.1 m/s. Present work is concentrated on the application of this subsea robot on a maintenance task at the Brazilian underwater template OCTOS-1000. For this experiments the robot is integrated in a large mock-up which simulates a quarter section of this template. (orig.)
T-2 toxin, a highly toxic member of the type-A trichothecenes, is produced by various Fusarium moulds that can potentially affect human health. It is strongly cytotoxic for human hematopoietic progenitors. Alimentary toxic aleukia (ATA), a disease typically associated with human, is primarily induced by T-2 toxin. A comparison of the metabolism of T-2 toxin incubated with hepatocytes of rats, piglets, chickens, and the hepatic subcellular fractions (microsomes and cytosol) of piglets, chickens, rats, and carp (common carp and grass carp) was carried out. The activities of the recombinant pig CYP3A29 on the transformation of T-2 and HT-2 toxins were preliminary studied. Metabolites were identified by novel LC/MS-IT-TOF. Qualitative similarities and differences across the species were observ...
In the CERN approach to the design of a neutrino factory, the repetition frequency of the proton beam is high enough to consider stationary solid targets as a viable solution for multi-MW beams. The target consists of high density tantalum spheres of 2 mm diameter which can efficiently be cooled by passing a high mass flow He-gas stream through the voids between the Ta-granules. Very small thermal shocks and stresses will arise in this fine grained structure due to the relatively long burst of 3.3 ms from the SPL-proton linac. In a quadruple target system where each target receives only one quarter of the total beam power of 4 MW, conservative temperature levels and adequate lifetimes of the target are estimated in its very high radiation environment. A conceptual design of the integration of the target into the magnetic horn-pion-collector is presented.
Truck haulage systems are widely used in open pit mining operations. Thanks to the rapid development and use of personal computers, simulation of haulage systhems involving Computer Aided Design (CAD) facilities and animation has recently become an attractive alternative in the Swedish Mining Industrie compared to the conventional simulations. Furthermore, when planning or simulating hauling operations, it is important to be able to accurately calculate velocities, cycle times and fuel consumption for truck fleets under varying conditions. It is the objective of this paper to present the basic features and principles of two microcomputer programs, TRUCKPER and METAFORA. These programs can be used as an integrated tool for evaluating truck haulage systems in surface mines. (orig.).
Summary Background Pemphigus vulgaris and pemphigus foliaceus are rare, potentially life-threatening, autoimmune disorders characterized by antibodies to epidermal adhesion molecules. Clinical characteristics are painful chronic erosions of mucous membranes and of the skin. There are only few published studies on the impact of the disease on the health status (HS) of patients with these conditions. Objectives To assess the impact of disease on the HS of patients with pemphigus. Methods Fifty-eight patients enrolled at the Bullous Skin Diseases Unit of IDI-IRCCS in the period January-June 2006 were assessed for their HS using the Medical Outcomes Study 36-item short form health survey (SF-36) questionnaire and for anxiety and depression using the Institute for Personality and Ability Testin...
By means of an analogous simulator, which can simulate a power supply system, a method to determine the transfer function of a Power System Stabilizer (PSS) is developed. The purpose of the PSS is to damp unwanted electro-mechanical oscillations. The method is very systematic and there is no need for specified values of the parameters used in the system. It is assumed that the power generator system is linear for small variations. The system can be considered to be a black box. Measurements executed by means of this method are completely controlled by the person who enforces the measurement. By applying this method carefully, irregularities are almost out of the question. The equipment necessary are a PC with two AD-ports and an adjustable sinus-generator. A comparison is made with a more traditional method, in which a spectrum analyzer is used. 4 figs., 7 refs.
Objective: Given the increasing popularity of motorcycle riding and heightened risk of injury or death associated with being a rider, this study explored rider behavior as a determinant of rider safety and, in particular, key beliefs and motivations that influence such behavior. To enhance the effectiveness of future education and training interventions, it is important to understand riders' own views about what influences how they ride. Specifically, this study sought to identify key determinants of riders' behaviors in relation to the social context of riding, including social and identity-related influences relating to the group (group norms and group identity) as well as the self (moral/personal norm and self-identity). Method: Qualitative research was undertaken via group discussions ...
A Real-Time Operating System(RTOS) is an Operating System(OS) intended for real-time applications. Benchmarking is a point of reference by which something can be measured. The QNX is a Real Time Operating System(RTOS) developed by QSSL(QNX Software Systems Ltd.) in Canada. The ELMSYS is the brand name of commercially available Personal Computer(PC) for applications such as Cabinet Operator Module(COM) of Digital Plant Protection System(DPPS) and COM of Digital Engineered Safety Features Actuation System(DESFAS). The ELMSYS PC Hardware is being qualified by KTL(Korea Testing Lab.) for use as a Cabinet Operator Module(COM). The QNX RTOS is being dedicated by Korea Atomic Energy Research Institute (KAERI). This paper describes the outline and benchmarking test results on Context Switching, Message Passing, Synchronization and Deadline Violation of QNX RTOS under the ELMSYS PC platform
This guide accompanies the following article: Gabrielle Poeschl, `What Family Organization Tells Us about Fairness and Power in Marital Relationships', Social and Personality Compass 1/1 (2007): 557-571, 10.1111/j.1751-9004.2007.00026.x Author's Introduction One thing that often strikes me, when I talk with people, is the human capacity to accept and defend surprising aspects of the social life. Thus, we have some feeling that the separation between the domestic and the public spheres has not always existed, but we are ready to assume that in the first human groups, men went out hunting to feed their family, while women stayed in the camp to take care of the children. Even in the face of evidence to the contrary, we are reluctant to question the opinion that men and women differ in persona...
Almost in all the major cities in Asian countries, residential buildings are characterized with high-rise and high density. Under this circumstance, achieving comfortable and healthy indoor environment with minimized energy consumption becomes a very challenging engineering and societal issue. While the wide use of air-conditioning helped to improve thermal comfort, health problems associated with poor indoor air qualities have appeared more frequently. The increased energy consumption is also a great concern in view of its impact on the energy economics of the region. Drawn from some of the onsite measurements and survey, and also the author's personal observation, some of the key issues are discussed in this paper. (author)
Twenty-four long-term survivors of Ewing's sarcoma were identified as being at risk for a second primary tumor. Among this group of patients followed from 3 to 22 y, 4 new bone tumors were observed, whereas 1.2 x 10"-"3 were expected. All new tumors arose in heavily irradiated areas. The risk associated with radiation after 3 years was 7.2 cases/million person-years per rad. The cumulative cancer risk over 10 years for irradiated patients was 35% (SE, 15.1%). Intensive chemotherapy (cyclophosphamide and vincristine administered in five or more courses) seemed to exert an enhancing effect, increasing the rate of development of new tumors.
The book presents a very good account of all aspects of protection from ionizing radiation. The quantities and units are given and defined used in nuclear physics and dosimetry. The effects of ionizing radiation on cells and on man are described. The principles are presented of radiation protection including limits and valid regulations and decrees. Also discussed is internal irradiation and its modelling. A great part of the book is devoted to aspects of monitoring persons, the living and working environment and to the determination of internal contamination. The system of radiation protection in Czechoslovakia is described and some practical questions are discussed of protection during radiodiagnosis and radiotherapy, in the nuclear fuel cycle, in the operation of nuclear power installations and in crack detection. In conclusion a survey is given of the population exposure from various natural and artificial sources. (M.D.). 57 figs., 34 tabs., 138 refs.
Several studies on individual control of the thermal indoor climate and indoor air quality are discussed. A distinction is made between the effect on health, the effect on comfort and the effect on performance. The underlying mechanisms are examined more closely, and concrete recommendations are made for future design norms. [Dutch] Een aantal studies op het gebied van beinvloeding van thermisch binnenklimaat en binnenluchtkwaliteit wordt besproken. Hierbij wordt onderscheid gemaakt tussen invloed op gezondheid, comfort en prestaties. Vervolgens wordt dieper ingegaan op achterliggende mechanismen en worden concrete aanbevelingen gedaan voor toekomstige ontwerpen.
Summary Status epilepticus or other brain-damaging insults launch a cascade of events that may lead to the development of epilepsy. MRI techniques available today, including T2- and T1-weighted imaging, functional MRI, manganese enhanced MRI (MEMRI), arterial spin labeling (ASL), diffusion tensor imaging (DTI), and phase imaging, can detect not only damage caused by status epilepticus but also plastic changes in the brain that occur in response to damage. Optimal balance between damage and recovery processes is a key for planning possible treatments, and noninvasive imaging has the potential to greatly facilitate this process and to make personalized treatment plans possible.
Abstract Background Despite the undeniable impact of systemic sclerosis (SS) on quality of life, only a few studies so far have focused on its psychiatric or psychological aspects. We aimed at assessing psychiatric symptoms and self-image in inpatients with SS and comparing them with patients with either a very mild skin condition or a serious skin condition. Methods Three groups were recruited: (i) 38 consecutive female inpatients with SS; (ii) 38 age-matched female outpatients with melanocytic naevi; (iii) 35 age-matched female inpatients with melanoma. All participants completed the Zung Anxiety Scale, the Zung Depression Scale and a self-report questionnaire measuring self-perceived personal qualities. Patients with SS were also clinically interviewed by a psychologist. Results The cli...
The Los Alamos Cost Estimating System (QUEST) is being converted to run on IBM personal computers. This very extensive estimating system is capable of supporting cost estimators from many different and varied fields. QUEST does not dictate any fixed method for estimating. QUEST supports many styles and levels of detail estimating. QUEST can be used with or without data bases. This system allows the estimator to provide reports based on levels of detail defined by combining work breakdown structures. QUEST provides a set of tools for doing any type of estimate without forcing the estimator to use any given method. The level of detail in the estimate can be mixed based on the amount of information known about different parts of the project. The system can support many different data bases simultaneously. Estimators can modify any cost in any data base.
Partial adrenalectomy is usually performed for the treatment of bilateral pheochromocytomas and in case of sporadic, monolateral tumors, to minimize the risk of adrenal failure, especially in younger patients. Due to the lack of consistent series, many issues such as correct surgical indications and technical aspects still need to be debated. From 2007 to 2010 we performed four unilateral partial adrenalectomies (3 aldosterone-producing adenomas and 1 cortisol-producing adenoma), and three bilateral subtotal adrenalectomies, consisting in total adrenalectomy on one side and partial adrenalectomy on the contralateral gland (3 bilateral pheochromocytomas in MEN IIa). In case of single tumor, partial adrenalectomy was carried out without adrenal vein ligation and the results were similar to t...
The purpose of this note is to provide guidance to those who have duties under the Health and Safety at Work Act and other relevant legislation. It gives guidance on the practical application of legislation, concerning radiotherapy equipment. Two particular issues arise out of the requirements of Regulation 33 of the Ionising Radiations Regulations 1985 (IRR85) in relation to equipment which is used for medical exposures. These are the requirement to select, install and maintain this type of equipment in such a way that it is capable of restricting, so far as reasonably practicable, the medical exposure of any person where this is compatible with the intended clinical purpose, including the need to ensure that equipment used for radiotherapy is properly calibrated, and the requirement to notify the Health and Safety Executive (HSE) when an incident occurs involving a malfunction or defect in any 'radiation equipment' which gives rise to a medical ...
Purpose. The paper introduces a novel design of air-core inductive sensors in printed circuit board (PCB) technology for a tongue control system. The tongue control system provides a quadriplegic person with a keyboard and a joystick type of mouse for interaction with a computer or for control of an assistive device. Method. Activation of inductive sensors was performed with a cylindrical, soft ferromagnetic material (activation unit). Comparative analysis of inductive sensors in PCB technology with existing hand-made inductive sensors was performed with respect to inductance, resistance, and sensitivity to activation when the activation unit was placed in the center of the sensor. Optimisation of the activation unit was performed in a finite element model. Results. PCBs with air-core indu...
This essay reviews key controversies in the history of the Darwinian research tradition: the Wilberforce-Huxley debate in 1860, early twentieth-century debates about the heritability of acquired characteristics and the consistency of Mendelian genetics with natural selection; the 1925 Scopes trial about teaching evolution; tensions about race, culture, and eugenics at the 1959 centenary celebration Darwin?s Origin of Species; adaptationism and its critics in the Sociobiology debate of 1970s and, more recently, Evolutionary Psychology; and current disputes about Intelligent Design. These controversies, I argue, are etched into public memory because they occur at the emotionally charged boundaries between public-political, technical-scientific, and personal-religious spheres of discourse. Ov...
Electric utilities have been surprised by recent opposition to the construction of very-high-voltage transmission lines, which met with little resistance in the past. Concerns over health and safety factors are associated with the increase in the number of such lines, although their presence has always been an inconvenience and a hazard for those living and working in the immediate vicinity. The new lines present additional hazards due to the continuous flow of small electric currents and the charges that build up in the area of the towers and lines. The lines are also a threat to persons wearing cardiac pacemakers. There is experimental evidence from the Soviet Union and the U.S. that electric and magnetic fields at the frequencies of such power lines can have serious biological effects on growth rates and the functioning of the central nervous system. Full disclosure that possible risks are involved and the opportunity to avoid these risks is a public ...
SummaryBackground Persistent Lyme Disease Symptoms (PLDS) have included fatigue, headaches, poor concentration and memory, lightheadedness, joint pain, and mood disturbances. Evidence-based guidelines committees disagree over the severity of PLDS. The 2004 International Lyme and Associated Diseases Society (ILADS) concluded that PLDS are severe. The 2006 Infectious Disease Society of America (IDSA) guidelines committee concluded that PLDS are nothing more than the "aches and pains of daily living" and an ad hoc International Lyme group concluded that PLDS are "symptoms common in persons who have never had Lyme disease." Hypothesis Clinical trials validate the severity of persistent Lyme disease symptoms. Evaluation of the Hypothesis There are 22 standardized instruments used to measure the...
Solid state nuclear track detectors (SSNTD) are widely used for radon measurements and CR-39 is one of the most popular SSNTD. In this work it was determined the calibration factor for radon concentration measurements through the passive method with CR-39 detectors. The detectors were put in a proper device (an adapted Lucas cell) and exposed to the standard radon concentration through the Pylon Model RN-150 flow through radon gas source. After exposure, the detectors were etched for 5.5 hours in a KOH solution at 80 deg C in a bath at a constant temperature. The track density was read in an Axiolab-Zeiss optical microscope, with nominal magnification of X10 connected to a video camera and to a personal computer. The calibration factor was obtained through the relation between standard radon concentration, track density and exposure time. (author)
Solid state nuclear track detectors (SSNTD) are widely used for radon measurements and CR-39 is one of the most popular SSNTD. In this work it was determined the calibration factor for radon concentration measurements through the passive method with CR-39 detectors. The detectors were put in a proper device (an adapted Lucas cell) and exposed to the standard radon concentration through the Pylon Model RN-150 flow through radon gas source. After exposure, the detectors were etched for 5.5 hours in a KOH solution at 80 deg C in a bath at a constant temperature. The track density was read in an Axiolab-Zeiss optical microscope, with nominal magnification of X10 connected to a video camera and to a personal computer. The calibration factor was obtained through the relation between standard radon concentration, track density and exposure time. (author)
The paper describes, for the Hausa farmers of Gidan Jatau in northern Nigeria, the distinct ways in which they see and understand (a) their close and distant environment and (b) their bodies' anatomy and physiology. These ways result in 'another geography' - of both space and being - which, however, may no longer now have the resonance it had in the early 1970s when the author lived in Gidan Jatau for two years as a guest. At that time, the spiritual dimensions of daily life were deemed important to the health and prosperity of each person and to the farmstead as a whole. The argument is made that the urban-centred literature on the bori possession-cult neglects the ordinary, anonymous spirits of house and field. Any serious archaeology of the landscape will need insights into this 'altern...
This paper addresses the influence of CHC on how the insider/outsider distinction is drawn and what consequences follow for the conduct of research. The paper outlines the methodological complexities faced by us whilst conducting our respective research projects in Hong Kong. In the studies reported in this paper we, the researchers, were insiders at one level as both of us have a degree of familiarity with Hong Kong being residents of the city. We were also insiders on a professional level in the contexts under study. However being ethnically non-Chinese positioned us as outsiders. Additionally, our Western-trained research selves accepted certain normative paradigms, whilst our own personal ethno-centricities tended to question these self-same paradigms. In sum, the research context for ...