WorldWideScience
1

Emotional/behavioral difficulties and adolescent obesity: effect of sex and Hispanic origin/race  

British Library Electronic Table of Contents (United Kingdom)

Abstract This study examines the relationship between emotional/behavioral difficulties and obesity among US adolescents aged 12-17 using parent-reported data for 11,042 adolescents in the National Health Interview Survey. Obesity was defined as body mass index (BMI) ?sex/age-specific 95th percentile BMI cut-points from the 2000 CDC Growth Charts. Types of emotional/behavioral difficulties were identified using the Strengths and Difficulties Questionnaire. Among females, emotional/behavioral difficulties were associated with obesity among non-Hispanic (NH) white and Hispanic adolescents (both those with interviews in English and interviews in Spanish). Among males, emotional/behavioral difficulties were associated with obesity among NH white adolescents and Hispanic males with interview...

2011-01-01

2

Regulation of Energy Metabolism Pathways by Estrogens and Estrogenic Chemicals and Potential Implications in Obesity Associated with Increased Exposure to Endocrine Disruptors  

UK PubMed Central (United Kingdom)

The prevalence of obesity among children, adolescents and adults has been dramatically increasing worldwide during the last several decades. The obesity epidemic has been recognized as one of...Full Text Available

2009-07-01

3

Molecular insights from bariatric surgery.  

Science.gov (United States)

Bariatric surgical procedures have become important therapeutic options for treatment of morbid obesity in both adults and adolescents co-morbidities of obesity such as glucose intolerance, type 2 diabetes (T2DM), metabolic syndrome, steatohepatitis, hyperlipidemia and cardiovascular disease. These co-morbidities of obesity have significant impacts on the overall quality of life of the individual and our society at large. Roux-en-Y gastric bypass (RYGB) and the relatively newer procedures of gastric banding (GB) and vertical sleeve gastrectomy (VSG) have proven to be efficacious in achieving rapid weight loss and reversing the comorbidities of obesity. Unfortunately, bariatric procedures are not without risks including micronutrient deficiency, failure to maintain lost weight, and mortality. Further, the resolution of T2DM has long been understood to precede weight loss, and this ...

2011-09-01

4

Secular changes in height, weight and body mass index in Hong Kong Children  

UK PubMed Central (United Kingdom)

BackgroundLarge population growth surveys of children and adolescents aged 6 to 18 y were undertaken in Hong Kong in 1963 and 1993. The global epidemic of obesity is a major public...Full Text Available

5

Diet, Exercise, Behavior: The Promise and Limits of Lifestyle Change  

UK PubMed Central (United Kingdom)

The prevalent surge in childhood and adolescent obesity within the past 3 decades poses a significant challenge for many pediatric clinicians who are charged with treating this condition. The...Full Text Available

2009-08-01

6

Steatohepatite non alcoolique chez une adolescente obese : une biopsie hepatique discutable  

British Library Electronic Table of Contents (United Kingdom)

The growing epidemic of juvenile obesity has prompted pediatricians to investigate obesity-related conditions in obese teenagers. We report a clinical case of severe hepatic fibrosis in an adolescent with severe and recent obesity. Because of elevated serum aminotransferase levels, abnormal hepatic ultrasonography and insulin resistance (impaired glucose tolerance), we suspected nonalcoholic steatohepatitis (NASH). Disease activity and fibrosis were confirmed on liver biopsy. Considering the risk of progression toward cirrhosis and its complications, and the pathological liver lesions, we started long-term medical monitoring and drug therapy to control weight loss. At present, although biopsy is the only validated way to establish the diagnosis of NASH, there is no consensus on its indicat...

2011-01-01

7

Obesity and periodontal disease  

UK PubMed Central (United Kingdom)

Obesity is characterized by the abnormal or excessive deposition of fat in the adipose tissue. Its consequences go far beyond adverse metabolic effects on health, causing an increase in oxidative stress,...Full Text Available

2010-04-01

8

Molecular insights from bariatric surgery  

British Library Electronic Table of Contents (United Kingdom)

Bariatric surgical procedures have become important therapeutic options for treatment of morbid obesity in both adults and adolescents co-morbidities of obesity such as glucose intolerance, type 2 diabetes (T2DM), metabolic syndrome, steatohepatitis, hyperlipidemia and cardiovascular disease. These co-morbidities of obesity have significant impacts on the overall quality of life of the individual and our society at large. Roux-en-Y gastric bypass (RYGB) and the relatively newer procedures of gastric banding (GB) and vertical sleeve gastrectomy (VSG) have proven to be efficacious in achieving rapid weight loss and reversing the comorbidities of obesity. Unfortunately, bariatric procedures are not without risks including micronutrient deficiency, failure to maintain lost weight, and mortalit...

2011-01-01

10

Management of obesity in menopause: Diet, exercise, pharmacotherapy and bariatric surgery  

British Library Electronic Table of Contents (United Kingdom)

Menopause is characterized by the progressive reduction of estrogens resulting to cessation of menses. It is associated with an increase of cardiovascular risk factors such as hyperglycemia, hypertension, dyslipidemia and of abdominal and/or selective visceral fat mass deposition. Obesity, a modern day epidemic, is promoted by an obesogenic environment that interacts with the genetic background. The result is a positive energy balance materialized by the accumulation of the adipose tissue. This process is marked by great individual variation. Obesity is also associated with the presence of cardiovascular risk factors. In this review, the main pathophysiologic processes for the increase of obesity in menopause and the possible effects of pre-menopausal obesity regarding the cessation of ova...

2010-01-01

12

Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice  

UK PubMed Central (United Kingdom)

Exercise promotes weight loss and improves insulin sensitivity. However, the molecular mechanisms mediating its beneficial effects are not fully understood. Obesity correlates with increased production...Full Text Available

2008-09-01

13

Maternal obesity and labour complications following induction of labour in prolonged pregnancy  

UK PubMed Central (United Kingdom)

ObjectiveTo investigate the effect of maternal obesity on mode of delivery following induction of labour (IOL) for prolonged pregnancy and subsequent intrapartum and neonatal complications.DesignRetrospective...Full Text Available

2011-04-01

14

School refusal and anxiety in adolescence: Non-randomized trial of a developmentally sensitive cognitive behavioral therapy.  

Science.gov (United States)

The main objectives were to evaluate efficacy and acceptability of a developmentally sensitive cognitive behavioral therapy for anxiety-based school refusal in adolescence. Twenty school-refusing adolescents meeting DSM-IV anxiety disorder criteria participated in a non-randomized trial, together with parents and school staff. Outcome was assessed at post-treatment and 2-month follow-up. Treated adolescents showed significant and maintained improvements across primary outcome variables (school attendance; school-related fear; anxiety), with medium to large effect sizes. Half of the adolescents were free of any anxiety disorder at follow-up. Additional improvements were observed across secondary outcome variables (depression; overall functioning; adolescent and parent self-efficacy). The treatment was rated as acceptable by adolescents, ...

2011-04-28

15

Prosocial effects of nicotine and ethanol in adolescent rats through partially dissociable neurobehavioral mechanisms  

UK PubMed Central (United Kingdom)

The widespread use of tobacco and alcohol among adolescents might be related to the ability of nicotine and ethanol to facilitate social interactions. To investigate the neurobehavioral mechanisms...Full Text Available

2009-11-01

16

Gene-Environment Correlation and Interaction in Peer Effects on Adolescent Alcohol and Tobacco Use  

UK PubMed Central (United Kingdom)

Peer relationships are commonly thought to be critical for adolescent socialization, including the development of negative health behaviors such as alcohol and tobacco use. The interplay between...Full Text Available

2008-07-01

17

A novel procedure for assessing the effects of drugs on satiation in baboons: effects of memantine and dexfenfluramine  

UK PubMed Central (United Kingdom)

RationaleProcedures for studying the effects of medications on satiation will assist the development of obesity medications.ObjectivesFull Text Available

2008-09-01

18

Effect of Smoking Scenes in Films on Immediate Smoking  

UK PubMed Central (United Kingdom)

BackgroundThe National Cancer Institute has concluded that exposure to smoking in movies causes adolescent smoking and there are similar results for young adults.Full Text Available

2010-04-01

19

Food reward functions as affected by obesity and bariatric surgery  

British Library Electronic Table of Contents (United Kingdom)

Roux-en-Y gastric bypass surgery (RYGB) remains to be the most effective long-term treatment for obesity and its associated comorbidities, but the specific mechanisms involved remain elusive. Because RYGB patients appear to no longer be preoccupied with thoughts about food and are satisfied with much smaller meals and calorically dilute foods, brain reward mechanisms could be involved. Just as obesity can produce maladaptive alterations in reward functions, reversal of obesity by RYGB could normalize these changes or even further reset the food reward system through changes in gut hormone secretion, aversive conditioning and/or secondary effects of weight loss. Future studies with longitudinal assessments of reward behaviors and their underlying neural circuits before and after surgery wil...

2011-01-01

20

Structured exercise training programme versus hypocaloric hyperproteic diet in obese polycystic ovary syndrome patients with anovulatory infertility: a 24-week pilot study  

British Library Electronic Table of Contents (United Kingdom)

BACKGROUNDLifestyle modifications are successfully employed to treat obese and overweight women with polycystic ovary syndrome (PCOS). The aims of the current pilot study were (i) to compare the efficacy on reproductive functions of a structured exercise training (SET) programme with a diet programme in obese PCOS patients and (ii) to study their clinical, hormonal and metabolic effects to elucidate potentially different mechanisms of action.METHODSForty obese PCOS patients with anovulatory infertility underwent a SET programme (SET group, n = 20) and a hypocaloric hyperproteic diet (diet group, n = 20). Clinical, hormonal and metabolic data were assessed at baseline, and at 12- and 24-week follow-ups. Primary endpoint was cumulative pregnancy rate.RESULTSThe two groups had similar demogra...

2008-01-01

21

Transcranial magnetic stimulation in adolescent depression  

British Library Electronic Table of Contents (United Kingdom)

Objective: There are few safe and effective biological treatments for major depression in adolescents. We aimed to report the use of repetitive transcranial magnetic stimulation (rTMS) as a treatment for adolescents with this condition. Methods: The first two subjects in a double-blind, sham-controlled trial of rTMS that is evaluating the efficacy and safety of rTMS in depressed adolescents are described. Clinical response was assessed at baseline and at the end of each week. The following scales were used: Montgomery-Asberg Depression Rating Scale, Clinical Global Impression-Severity Scale, Beck Depression Inventory and Centre for Epidemiological Studies - Depression - Child Scale. A battery of cognitive tests was also used at several intervals to measure potential change in neuropsycholo...

2006-01-01

22

Weight-control behaviors and subsequent weight change among adolescents and young adult females123  

UK PubMed Central (United Kingdom)

Background: Little is known about the effectiveness of behavioral strategies to prevent long-term weight gain among adolescents and young adults.Objective: The objective...Full Text Available

2010-01-01

23

Table of Contents  

British Library Electronic Table of Contents (United Kingdom)

Abstract Overall Numbers Small, But Study Finds SSRI Exposure, Autism Link Additional Drug Safety, Efficacy Data Needed for Pediatric Bipolar Disorder SGA Safety and Efficacy in Children and Adolescents Aripiprazole Safety and Tolerability for Irritability in Autism No Lisdexamfetamine Effect on Sleep Disturbances in Children With ADHD Sickle Cell Disease With Comorbid Depression Homeopathy in Psychiatry Manic Symptoms Induced by Marijuana in a Healthy Adolescent New Warnings Safety Labeling Changes

2011-01-01

24

A Motivation-Focused Weight Loss Maintenance Program is an Effective Alternative to a Skill-Based Approach  

UK PubMed Central (United Kingdom)

ObjectiveMaintaining weight loss is a major challenge in obesity treatment. Individuals often indicate that waning motivation prompts cessation of effective weight...Full Text Available

2011-02-01

25

A Double Blind, Placebo-Controlled, Randomized Crossover Study of the Acute Metabolic Effects of Olanzapine in Healthy Volunteers  

UK PubMed Central (United Kingdom)

Background and RationaleAtypical antipsychotics exhibit metabolic side effects including diabetes mellitus and obesity. The adverse events are preceded by acute worsening of oral...Full Text Available

26

An animal model of social instability stress in adolescence and risk for drugs of abuse  

British Library Electronic Table of Contents (United Kingdom)

There is increasing evidence that adolescence, like early life, is a sensitive period in which ongoing brain development can be influenced by environmental factors. This review describes our use of social instability as a model of mild adolescent social stress, its effects on social interactions and on hypothalamic?pituitary?adrenal function over the course of the procedure and in response to new stressors. The effects of social instability are sex-specific, with qualitative differences between the sexes on HPA function over the course of the stressor procedure, and with greater effects in males on behaviour observed during the social instability and greater effects in females on behavioural responses to drugs of abuse into adulthood, long after the stress exposure. The results from invest...

2010-01-01

27

The weight of obesity in evaluating others: a mere proximity effect.  

Science.gov (United States)

Previous research demonstrates that we tend to derogate individuals who are perceived to be in a social relationship with stigmatized persons. Two experiments examined whether this phenomenon also occurs for individuals seen in the presence of an obese person and whether a social relationship is necessary for stigmatization to spread. The results from both experiments revealed that a male job applicant was rated more negatively when seen with an overweight compared to a normal weight female and that just being in the mere proximity of an overweight woman was enough to trigger stigmatization toward the male applicant. Experiment 2 examined possible moderating effects of the proximity finding. Applicants seated next to heavy (vs. average weight) individuals were denigrated consistently regardless of the perceived depth of the relationship, the participant's anti-fat attitudes or gender, and whether or not positive information was presented ...

2003-01-01

28

A participatory parent-focused intervention promoting physical activity in preschools: design of a cluster-randomized trial  

UK PubMed Central (United Kingdom)

BackgroundWith rates of childhood obesity increasing, physical activity (PA) promotion especially in young children has assumed greater importance. Given the limited effectiveness...Full Text Available

29

[Study of body composition by potassium-40 measurement in patients with breast and uterine cancer].  

Science.gov (United States)

Total potassium was assayed in 150 normal weight and obese females (cervical carcinoma-52, endometrial carcinoma-25 and breast cancer-73) by measurements of 40K spontaneous radiation in a low-background chamber. Control group included 30 healthy and 25 obese females. Computations of body cell and extracellular mass and fat were carried out on the basis of the said measurements. Extracellular fluid volume was measured in 38 patients by X-ray fluorescence method using sodium bromide. The results pointed to a body cell mass deficit matched by increased extracellular mass due to a higher fat level in patients with breast, endometrial and cervical carcinoma. The said correlation was particularly pronounced in obese patients. The beneficial effect of treatment was more often observed in patients with normal body weight. PMID:3739295

1986-01-01

30

Soy isoflavones, diet and physical exercise modify serum cytokines in healthy obese postmenopausal women  

British Library Electronic Table of Contents (United Kingdom)

Objectives: Evaluate the effect of diet, physical exercise, and a daily oral intake of a soy isoflavones extract (Fisiogen) contained 200mg of Glycine max, which corresponded to 80mg of isoflavone (60.8mg of genistein, 16mg of daidzein and 3.2mg of glicitein) on leptin and other adipokines plasma levels in healthy obese postmenopausal women. Methods: A multicentric randomized longitudinal prospective cohort study was conducted in a sample of 87 healthy obese postmenopausal women. Patients were randomly assigned to a 1200kcal diet and exercise group (control group) or a group of 1200kcal diet, exercise, and daily oral intake of daily oral intake of a soy isoflavones extract (Fisiogen) contained 200mg of Glycine max, which corresponded to 80mg of isoflavone (60.8mg of genistein, 16mg of daid...

2011-01-01

31

Sex-specific influence of exposure to bisphenol-A between adolescence and young adulthood on mouse behaviors  

British Library Electronic Table of Contents (United Kingdom)

Bisphenol-A (BPA) is one of the most common environmental endocrine disrupters and has a wide range of effects on central nervous system. Adolescence is another important developmental period besides the early critical prenatal and neonatal periods. In the present study, we exposed mice to BPA (40, 400 mg/kg/d) between adolescence and young adulthood for 8 weeks and investigated its effects on the non-reproductive behaviors. In open field tests, rearing and grooming sex differences were abolished by BPA exposure. In the elevated plus maze test, the number of open arm entries, the time spent in open arms, and the number of unprotected head dips in the center area were reduced in males but increased in females by BPA at 40 or 400 mg/kg/d, thus eliminating or reversing sex differences in thes...

2011-01-01

32

The Long-Term Effects of Prematurity and Intrauterine Growth Restriction on Cardiovascular, Renal, and Metabolic Function  

UK PubMed Central (United Kingdom)

Objective. To determine relative influences of intrauterine growth restriction (IUGR) and preterm birth on risks of cardiovascular, renal, or metabolic dysfunction in adolescent...Full Text Available

2010-01-01

33

Sunbed use during adolescence and early adulthood is associated with increased risk of early-onset melanoma  

UK PubMed Central (United Kingdom)

Sunbed use is associated with increased risk of melanoma. Younger people might be more susceptible to the carcinogenic effects of ultraviolet radiation. We investigated the association between...Full Text Available

2011-05-01

34

Neonatal E. coli infection alters glial, cytokine, and neuronal gene expression in response to acute amphetamine in adolescent rats  

UK PubMed Central (United Kingdom)

Neonatal bacterial infection in rats alters the responses to a variety of subsequent challenges later in life. Here we explored the effects of neonatal bacterial infection on a subsequent drug...Full Text Available

2010-04-19

35

Sulfation of chitosan oligomers enhances their anti-adipogenic effect in 3T3-L1 adipocytes  

British Library Electronic Table of Contents (United Kingdom)

Inhibition of adipogenesis and lipid accumulation has a very crucial role to prevent obesity. Low molecular weight (LMW) chitosan is known to inhibit fat accumulation and adipogenesis. (N,O)-sulfated chitosan is a sulfation derivative of chitosan oligomers, and its anti-obesity effect is not yet reported. In this study, it has been reported that (N,O)-sulfated chitosan significantly decreased lipid accumulation, an indicator for adipogenesis, in differentiating 3T3-L1 preadipocyte cells. Furthermore, mRNA expressions and protein levels of key adipogenic markers such as peroxisome prolifetor-activated receptor (PPAR)-@c and CCAAT-enhancer binding protein (C/EBP)-@a were considerably decreased by (N,O)-sulfated chitosan treatment. As a consequence, sulfation of LMWC remarkably increased its ...

2011-01-01

36

The growth factor from plerocercoid larvae of the tapeworm, Spirometra mansonoides, stimulates growth but is not diabetogenic.  

Science.gov (United States)

A factor produced by plerocercoids of the tapeworm Spirometra mansonoides is similar to human growth hormone (hGH) in that it stimulates body growth, binds to hGH receptors, cross-reacts with anti-hGH antibodies, and has lactogenic and insulin-like activities. The purpose of this study was to determine whether plerocercoid growth factor (PGF) is similar to hGH in expressing diabetogenic activity in the genetically obese (ob/ob) mouse. To determine an effective dose for use in the obese mice, the ability of daily injections of PGF to stimulate growth of phenotypically normal mice of the same strain was assessed in a 10-day weight gain assay. Injections of PGF stimulated a dose-dependent weight gain (r = 0.83) and 25 ng eq/day of PGF stimulated a response not significantly different from that produced by 100 micrograms of bovine growth hormone/day. Diabetogenicity was assessed using fasting blood glucose and glucose tolerance ...

1989-06-01

37

Efficacy and safety of second-generation antipsychotics in children and adolescents with psychotic and bipolar spectrum disorders: Comprehensive review of prospective head-to-head and placebo-controlled comparisons  

British Library Electronic Table of Contents (United Kingdom)

Objective: To review data on efficacy and safety of second-generation antipsychotics (SGAs) in children and adolescents with psychotic and bipolar spectrum disorders. Methods: Medline/PubMed/Google Scholar search for studies comparing efficacy and/or tolerability: (i) between two or more SGAs; (ii) between SGAs and placebo; and (iii) between at least one SGA and one first-generation antipsychotic (FGA). The review focused on three major side-effect clusters: 1. body weight, body mass index, and cardiometabolic parameters, 2. prolactin levels, and 3. neuromotor side effects. Results: In total, 34 studies with 2719 children and adolescents were included. Studies lasted between 3weeks and 12months, with most studies (79.4%) lasting 3months or less. Nine studies (n=788) were conducted in patie...

2011-01-01

38

(?) Epigallocatechin gallate suppresses the differentiation of 3T3-L1 preadipocytes through transcription factors FoxO1 and SREBP1c  

UK PubMed Central (United Kingdom)

Tea catechin is one of the compounds that are closely related to obesity and insulin sensitivity. In order to determine the effect of catechin on adipocyte differentiation, we treated 3T3-L1 preadipocytes...Full Text Available

2010-06-01

39

Systematic Function-Based Intervention for Adolescents with Emotional and Behavioral Disorders in an Alternative Setting: Broadening the Context  

Science.gov (United States)

Three adolescents (ages 14-17) with emotional and behavioral disorders displayed chronic disruptive behavior in their self-contained classrooms at a self-contained alternative school. A descriptive functional behavioral assessment was conducted for each student. Data from file review, structured interviews, and direct observations were used to identify the functions of their disruptive behaviors. Then, function-based interventions were systematically constructed for each student and implemented for an extended period (nearly 6 weeks) within the most problematic situation in their classrooms. The interventions improved each student's behavior and the effects maintained during follow-up and generalized to instruction in a nonintervention classroom. Social validity data comparing the interventions to baseline practices revealed the function-based intervention had moderately higher social validity among teachers and substantially higher social ...

2011-02-01

40

Second generation antipsychotics (SGAs) for non-psychotic disorders in children and adolescents: A review of the randomized controlled studies  

British Library Electronic Table of Contents (United Kingdom)

In children and adolescents the Second Generation Antipsychotics (SGAs) represent the class of psychotropic drugs whose use has grown more significantly in recent years: they are primarily used for treatment of patients with disruptive behavior disorders, mood disorders and pervasive developmental disorders or mental retardation. In order to compare the efficacy and tolerability of antipsychotics against placebo or each other, a systematic Medline/PubMed search for randomized, double blind studies on SGA in patients younger than 18years of age at enrolment, was conducted. Papers on schizophrenia, discussed in another article of this specific issue, were excluded by the efficacy analysis. A set of standard efficacy and safety indices, such as treatment effect sizes (ES), the Numbers Needed ...

2011-01-01

41

Changing patterns of neuropsychological functioning in children living at high altitude above and below 4000-m: a report from the Bolivian Children Living at Altitude (BoCLA) study  

British Library Electronic Table of Contents (United Kingdom)

Abstract The brain is highly sensitive to environmental hypoxia. Little is known, however, about the neuropsychological effects of high altitude residence in the developing brain. We recently described only minor changes in processing speed in native Bolivian children and adolescents living at approximately 3700-m. However, evidence for loss of cerebral autoregulation above this altitude (4000-m) suggests a potential threshold of hypoxia severity over which neuropsychological functioning may be compromised. We conducted physiological and neuropsychological assessments in 62 Bolivian children and adolescents living at La Paz (-3700-m) and El Alto (-4100-m) in order to address this issue. Groups were equivalent in terms of age, gender, social class, schooling, parental education and genetic ...

2011-01-01

42

Overweight and obesity among school-going children of Lucknow city  

UK PubMed Central (United Kingdom)

Background:Childhood obesity is increasingly being observed with changing lifestyles of families. The magnitude of overweight ranges from 9% to 27.5% and obesity ranges...Full Text Available

2011-05-01

43

Lipotoxic heart disease in obese rats: Implications for human obesity  

UK PubMed Central (United Kingdom)

To determine the mechanism of the cardiac dilatation and reduced contractility of obese Zucker Diabetic Fatty rats, myocardial triacylglycerol (TG) was assayed chemically and morphologically. TG was...Full Text Available

2000-02-15

44

Epidemiology of underweight and overweight-obesity among term pregnant Sudanese women  

UK PubMed Central (United Kingdom)

BackgroundThe increasing prevalence of obesity in young women is a major public health concern. Few data are available concerning the epidemiology of malnutrition especially obesity...Full Text Available

45

Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice  

UK PubMed Central (United Kingdom)

Uncoupling protein 2 (UCP2) maps to a region on distal mouse chromosome 7 that has been linked to the phenotypes of obesity and type II diabetes. We recently reported that UCP2 expression is increased...Full Text Available

1998-03-31

46

Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis*  

UK PubMed Central (United Kingdom)

Adipocyte death has been reported in both obese humans and rodents. However, its role in metabolic disorders, including insulin resistance, hepatic steatosis, and inflammation associated with obesity...Full Text Available

2010-01-29

47

Sida rhomboidea. Roxb Leaf Extract Down-Regulates Expression of PPAR?2 and Leptin Genes in High Fat Diet Fed C57BL/6J Mice and Retards in Vitro 3T3L1 Pre-Adipocyte Differentiation.  

Science.gov (United States)

Sida rhomboidea. Roxb leaf extract (SRLE) is being used by the populace of North-East India to alleviate symptoms of diabetes and obesity. We have previously reported its hypolipidemic and anti-diabetic properties. In this study, we report the effect of SRLE on (i) in vivo modulation of genes controlling high fat diet (HFD) induced obesity and (ii) in vitro 3T3L1 pre-adipocyte differentiation and leptin release. Supplementation with SRLE significantly prevented HFD induced increment in bodyweight, plasma lipids and leptin, visceral adiposity and adipocyte hypertrophy. Also, SRLE supplementation reduced food intake, down regulated PPAR?2, SREBP1c, FAS and LEP expressions and up-regulated CPT-1 in epididymal adipose tissue compared to obese mice. In vitro adipogenesis of 3T3L1 pre-adipocytes was significantly retarded in the presence of SRLE extract. Also decreased triglyceride accumulation, leptin ...

2011-07-19

48

Food Advertising and Marketing Directed at Children and Adolescents in the US  

UK PubMed Central (United Kingdom)

In recent years, the food and beverage industry in the US has viewed children and adolescents as a major market force. As a result, children and adolescents are now the target of intense and specialized...Full Text Available

49

Truancy and Escalation of Substance Use During Adolescence*  

UK PubMed Central (United Kingdom)

Objective:The aim of this study was to examine the relationship between truancy and escalation of substance use during adolescence and to explore potential mechanisms of this relationship.Method:Using...Full Text Available

2010-01-01

50

Is Maternal Marriage Beneficial for Low-Income Adolescents?  

UK PubMed Central (United Kingdom)

The present study investigated the association of mothers’ marriage and changes in young adolescents’ cognitive and socioemotional development and changes in family processes....Full Text Available

2009-01-01

51

Developmental Neurocircuitry of Motivation in Adolescence: A Critical Period of Addiction Vulnerability  

UK PubMed Central (United Kingdom)

ObjectiveEpidemiological studies indicate that experimentation with addictive drugs and onset of addictive disorders is primarily concentrated in adolescence and...Full Text Available

2003-06-01

52

An empirical analysis of factors affecting adolescent attachment in adoptive families with homosexual and straight parents  

British Library Electronic Table of Contents (United Kingdom)

Data were collected on 154 adoptive families with gay/lesbian and straight adoptive parents (154 parent respondents and 210 adolescent respondents). This study was principally interested in factors affecting adolescent attachment including parent sexual orientation, adolescent and parent life satisfaction, and parent level of relationship satisfaction with their adopted child as well as other key parent, child and adoption characteristics. The results suggest that higher level of adopted adolescent attachment to parents is not related to adoptive parent sexual orientation. Adolescent attachment to parents is related to adolescent life satisfaction; parent level of relationship satisfaction with their adopted child, number of placements prior to adoption, and adolescent's current age. Adole...

2009-01-01

53

Prosocial effects of nicotine and ethanol in adolescent rats through partially dissociable neurobehavioral mechanisms  

Science.gov (United States)

The widespread use of tobacco and alcohol among adolescents might be related to the ability of nicotine and ethanol to facilitate social interactions. To investigate the neurobehavioral mechanisms underlying the prosocial effects of nicotine and ethanol, we focused on social play behavior, the most characteristic social activity in adolescent rats. Social play behavior is rewarding, and it is modulated through opioid, cannabinoid and dopaminergic neurotransmission, which are also involved in the reinforcing properties of nicotine and ethanol. We found that nicotine and ethanol increased social play, without affecting locomotion or social exploration. Their effects depended on the level of social activity of the partner, and were comparable in familiar and unfamiliar environments. At doses that increased social play, nicotine and ethanol had no anxiolytic effects in the elevated ...

2009-08-05

54

Abdominal adipose tissue distribution in obese children. US versus CT measurements; Valutazione della distribuzione del tessuto adiposo addominale nei bambini obesi. Confronto tra ecografia e Tomografia Computerizzata  

Energy Technology Data Exchange (ETDEWEB)

Computed Tomography (CT) and, more recently, ultrasound (US), have proved excellent tools for quantifying adipose tissue distribution. Body fat distribution is an important factor in the treatment of obesity and its complications. In this work it is investigated the correlation between CT and US measurements in pediatric obesity. Forty obese children and adolescents aged 4.1-14.8 years were submitted to CT and US. Intra-abdominal, subcutaneous and total body fat were calculated (in cm{sup 2}), with the CT image analysis software. The rectus muscle-spine and rectus muscle-aorta distances, as indicative of visceral fat thickness, were measured on US images with(out) compression. The distance between skin fat and fat-rectus muscle interfaces was measured as subcutaneous fat thickness. US-CT findings have been compared with other morphometric variables-i.e., patient's (ideal) body weight and skin ...

1999-12-01

56

Genetic factors for resistance to diet-induced obesity and associated metabolic traits on mouse chromosome 17  

British Library Electronic Table of Contents (United Kingdom)

Obesity is associated with increased susceptibility to dyslipidemia, insulin resistance, and hypertension, a combination of traits that comprise the traditional definition of the metabolic syndrome. Recent evidence suggests that obesity is also associated with the development of nonalcoholic fatty liver disease (NAFLD). Despite the high prevalence of obesity and its related conditions, their etiologies and pathophysiology remains unknown. Both genetic and environmental factors contribute to the development of obesity and NAFLD. Previous genetic analysis of high-fat, diet-induced obesity in C57BL/6J (B6) and A/J male mice using a panel of B6-ChrA/J/NaJ chromosome substitution strains (CSSs) demonstrated that 17 CSSs conferred resistance to high-fat, diet-induced obesity. One of these CSS st...

2009-01-01

57

HEALTH POLICY INTERVENTION IN SCHOOLS PROMOTE PHYSICAL ACTIVITIES AMONG THE PUPILS  

DEFF Research Database (Denmark)

Now, more than ever, there are serious health concerns for obese and overweight children. Schools are the perfect setting for children to learn, and this influence can play an important role in preventing children from becoming obese and overweight. The study concerns the behaviors of Health Promoting School (HPS) according to a broad definition of HPS in World Health Organization (WHO), or dependent on schools own health promoting policies. The purpose of study research is to examine whether promoting physical activity among the children at schools in relation to a school health policy such as Food and Nutrition Policy (FNP). This was determined through the comparisons between the FNP based schools and non policy based schools. The study undertook surveys among school food coordinators in the selected Danish primary schools through a web-based questionnaire. The questions in the survey were more focused on physical activity in internal and ...

58

Dental caries in adolescents with attention deficit hyperactivity disorder: a population-based follow-up study  

British Library Electronic Table of Contents (United Kingdom)

Blomqvist M, Ahadi S, Fernell E, Ek U, Dahllf G. Dental caries in adolescents with attention deficit hyperactivity disorder: a population-based follow-up study. Eur J Oral Sci 2011; 119: 381-385. 2011 Eur J Oral Sci This study tested the hypothesis that adolescents with attention deficit hyperactivity disorder (ADHD) exhibit a higher prevalence of caries than adolescents in a control group. Thirty-two adolescents with ADHD and a control group of 55 adolescents from a population-based sample, all 17-yr of age, underwent a clinical and radiographic dental examination. The mean--SD number of decayed surfaces (DS) was 2.0--2.2 in adolescents with ADHD and 0.9--1.4 in adolescents of the control group. Thirty-one per cent of the adolescents in the ADHD group had no new caries lesions (DS-=-0) co...

2011-01-01

59

Attitudes toward obesity in obese persons: a matched comparison of obese women with and without binge eating.  

Science.gov (United States)

No research has compared expressions of weight bias across different subgroups of obese individuals. This study compared attitudes toward and beliefs about obesity in women with and without binge eating disorder (BED) and examined whether these attitudes are related to psychological factors. Fifty obese women with BED were compared with an age- and body mass index (BMI)-matched group of 50 obese women without BED on a battery of established measures of anti-fat attitudes and beliefs about weight controllability and psychological factors (self-esteem, depression, and eating disorder features). The ageand BMI-matched groups did not differ with respect to beliefs about obesity or attitudes toward obese persons, or in self-esteem or depression. Correlational analyses conducted separately within each group revealed that women with BED who reported more favorable ...

2010-01-27

60

Subjective effects to cannabis are associated with use, abuse and dependence after adjusting for genetic and environmental influences  

British Library Electronic Table of Contents (United Kingdom)

Background Previous reports in adults have suggested that the effects experienced after cannabis use can be described in terms of positive and negative subtypes that are heritable and are associated with abuse and dependence. This study extends existing research by inclusion of adolescents and young adults in an offspring of twins design which makes it possible to take into account genetic and environmental risks for substance use disorder. Methods Data were collected from 725 twin members of the Vietnam Era Twin Registry, 839 of their 12-32 year old biological offspring and 427 mothers. Offspring who had ever used cannabis (n=464) were asked the degree to which they typically experienced 13 subjective effects shortly after using cannabis. Latent class analysis (LCA) was used to derive sub...

2009-01-01

61

A preliminary study of sleep in adolescents with bipolar disorder, ADHD, and non-patient controls  

British Library Electronic Table of Contents (United Kingdom)

Mullin BC, Harvey AG, Hinshaw SP. A preliminary study of sleep in adolescents with bipolar disorder, ADHD, and non-patient controls.-Bipolar Disord 2011: 13: 425-432. 2011 The Authors.-Journal compilation 2011 John Wiley & Sons A/S. Objectives:- To compare the sleep of adolescents with bipolar disorder (BD) to groups of adolescents with attention-deficit hyperactivity disorder-combined type (ADHD-C) and those without psychopathology. Methods:- A sample of 13 adolescents diagnosed with BD who were not in the midst of a mood episode, 14 adolescents with ADHD-C, and 21 healthy controls, all between the ages of 11 and 17 years served as participants. They were psychiatrically evaluated using a structured diagnostic interview and completed four nights of in-home sleep monitoring using actigraph...

2011-01-01

62

Uneven dietary development: linking the policies and processes of globalization with the nutrition transition, obesity and diet-related chronic diseases  

UK PubMed Central (United Kingdom)

In a "nutrition transition", the consumption of foods high in fats and sweeteners is increasing throughout the developing world. The transition, implicated in the rapid rise of obesity and diet-related...Full Text Available

63

Serum protein binding and the role of increased alpha 1-acid glycoprotein in moderately obese male subjects.  

UK PubMed Central (United Kingdom)

Serum protein and lipid concentrations as well as the serum protein binding of propranolol, diazepam and phenytoin were measured in normal weight and obese volunteers. Concentrations of alpha 1-acid...Full Text Available

1984-12-01

64

Prevention of cardiovascular disease: Obesity, diabetes and the metabolic syndrome  

UK PubMed Central (United Kingdom)

The current obesity pandemic is expected to result in considerable downstream morbidity, mortality and incremental costs to health care systems around the world. The major metabolic complications of...Full Text Available

2010-08-01

65

Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance  

UK PubMed Central (United Kingdom)

Obesity and metabolic syndrome result from excess calorie intake and genetic predisposition and are mechanistically linked to type II diabetes and accelerated body aging; abnormal nutrient and insulin...Full Text Available

2010-07-27

66

Influence of obesity on the metabolism of apolipoprotein B in humans.  

UK PubMed Central (United Kingdom)

The influence of obesity on the metabolism of apolipoprotein B (apo B) in very low density lipoprotein (VLDL), intermediate density lipoprotein (IDL), and low density lipoprotein (LDL) was investigated...Full Text Available

1985-08-01

67

Do the Obese Have Lower Body Temperatures? A New Look at a Forgotten Variable in Energy Balance  

UK PubMed Central (United Kingdom)

Understanding the pathogenesis of obesity is now more important than ever, given the remarkable world-wide epidemic. This paper explores the potential role of core temperature in energy balance, and...Full Text Available

2009-01-01

68

Adipose Tissue Gene Expression of Factors Related to Lipid Processing in Obesity  

UK PubMed Central (United Kingdom)

BackgroundAdipose tissue lipid storage and processing capacity can be a key factor for obesity-related metabolic disorders such as insulin resistance and diabetes. Lipid uptake is...Full Text Available

69

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes  

UK PubMed Central (United Kingdom)

Acquired resistance to the action of insulin to stimulate glucose transport in skeletal muscle is associated with obesity and promotes the development of type 2 diabetes. In skeletal muscle,...Full Text Available

2008-05-01

70

AICAR inhibits adipocyte differentiation in 3T3L1 and restores metabolic alterations in diet-induced obesity mice model  

UK PubMed Central (United Kingdom)

BackgroundObesity is one of the principal causative factors involved in the development of metabolic syndrome. AMP-activated protein kinase (AMPK) is an energy sensor that regulates...Full Text Available

71

Electromagnetic fields - introduction to relevant issues  

International Nuclear Information System (INIS)

This introductory paper surveys potential sources of electric magnetic, and electro-magnetic fields. Various cases are discussed to exemplify the total frequency range: nuclear magnetic resonance tomography, high-voltage transmission lines, transformer stations, effect lighting balls, military transmitters, transmitter towers of the Postal Services and other operators, mobile radiotelephone equipment, large broadcasting transmitters, radar radiation, high-frequency heat therapy. There is evidence suggesting that electric, magnetic and electro-magnetic fields may possibly represent a certain nuisance or health hazard even at field strength occuring in equipment used for every-day-life purposes, with an emphasis on their possible actions and effects in children and adolescents. The author discusses, in conclusion, the aerial equipment ordinance issued by Lower Saxony. (Uhe).

1993-06-01

72

Undiagnosed osteoid osteoma of the spine presenting as painful scoliosis from adolescence to adulthood: a case report  

UK PubMed Central (United Kingdom)

Presented here is a case of a young woman, with an undiagnosed osteoid osteoma of the spine, which presented with painful scoliosis in adolescence and was treated by bracing until her accession to adulthood....Full Text Available

73

Tobacco use amongst out of school adolescents in a Local Government Area in Nigeria  

UK PubMed Central (United Kingdom)

IntroductionOut-of-school adolescents are often neglected when planning for tobacco prevention programmes whereas they are more vulnerable. Few studies exist in Nigeria about their...Full Text Available

74

Survival of HIV-Infected Adolescents on Antiretroviral Therapy in Uganda: Findings from a Nationally Representative Cohort in Uganda  

UK PubMed Central (United Kingdom)

BackgroundAdolescents have been identified as a high-risk group for poor adherence to and defaulting from combination antiretroviral therapy (cART) care. However, data on outcomes...Full Text Available

75

Socio-demographic disparity in oral health among the poor: a cross sectional study of early adolescents in Kilwa district, Tanzania  

UK PubMed Central (United Kingdom)

BackgroundThere is a lack of studies considering social disparity in oral health emanating from adolescents in low-income countries. This study aimed to assess socio-demographic...Full Text Available

76

Social Self-control, Sensation Seeking and Substance Use in Samples of US and Russian Adolescents  

UK PubMed Central (United Kingdom)

ObjectiveTo compare the relations of social self-control and sensation seeking with substance use across samples of US and Russian adolescents.Full Text Available

2010-05-01

77

Sexual self-disclosure in Cyberspace among Taiwanese adolescents: gender differences and the interplay of Cyberspace and real life.  

Science.gov (United States)

This study explored adolescents' sexual self-disclosure in real life and cyberspace, as well as gender differences of sexual self-disclosure in cyberspace. There were 115 male and 92 female adolescents who participated in this pretest and posttest survey. In general, the depth of sexual self-disclosure in real life was greater than in cyberspace, but the breadth of sexual selfdisclosure in both real life and cyberspace was equivalent. The cross-lagged panel analysis indicated that adolescents who were willing to self-disclose sexual topics in real life also selfdisclosed them more in cyberspace, and vice versa. Furthermore, sexual self-disclosure in both disclosing environments was mutually predicted by each other. The findings also indicated that cyberspace might not be a substitute channel of compensatory gratification for sexual self-disclosure in real life. As for gender differences, the breadth and depth of sexual ...

2006-02-01

78

Quantitative bone scintigraphy in children and adolescents. Age dependence of skeleton uptake  

International Nuclear Information System (INIS)

French ... Orig. Title Scintigraphie osseuse quantifiee chez l'enfant et l'adolescent - repartition selon l'age des taux de fixation de diverses pieces osseuses normales.

79

Mathematically Gifted Adolescents Have Deficiencies in Social Valuation and Mentalization  

UK PubMed Central (United Kingdom)

Many mathematically gifted adolescents are characterized as being indolent, underachieving and unsuccessful despite their high cognitive ability. This is often due to difficulties with social and emotional...Full Text Available

80

Evaluation of the PHQ-2 as a Brief Screen for Detecting Major Depression among Adolescents  

UK PubMed Central (United Kingdom)

ObjectiveTo examine the validity of the Patient Health Questionnaire - 2 (PHQ-2), a 2-item depression screening scale among adolescents.Full Text Available

2010-05-01

81

Depression and physical activity in a sample of nigerian adolescents: levels, relationships and predictors  

UK PubMed Central (United Kingdom)

BackgroundPhysical inactivity is related to many morbidities but the evidence of its link with depression in adolescents needs further investigation in view of the existing conflicting...Full Text Available

82

Characteristics of chronic non-specific musculoskeletal pain in children and adolescents attending a rheumatology outpatients clinic: a cross-sectional study  

UK PubMed Central (United Kingdom)

BackgroundChronic non-specific musculoskeletal pain (CNSMSP) may develop in childhood and adolescence, leading to disability and reduced quality of life that continues into adulthood....Full Text Available

83

Can Basic Risk Research Help in the Prevention of Childhood and Adolescent Depression? Examining a Cognitive and Emotional Regulation Approach  

UK PubMed Central (United Kingdom)

This paper aims to highlight ways in which basic research findings in the field of childhood and adolescent depression can help to inform and refine preventive intervention efforts. We selectively review...Full Text Available

2011-01-01

84

Calcium Requirements and Metabolism in Chinese-American Boys and Girls  

UK PubMed Central (United Kingdom)

Calcium requirements of North American adolescents were set at 1300 mg/day based on data from white girls. Calcium requirements for Asian-American adolescents have not been studied. Using metabolic...Full Text Available

2010-08-01

85

Reduction in incidence of deep sternal wound infections: Random or real?  

British Library Electronic Table of Contents (United Kingdom)

Objective Comorbidities predisposing cardiac surgical patients toward deep sternal wound infection, such as diabetes and obesity, are rising in the United States. Longitudinal analysis of risk factors, morbidity, and mortality was performed to assessed effects of these health trends on deep sternal wound infection rates. Methods In this retrospective analysis of all median sternotomies performed at a single institution from 1991 through 2006, demographic and surgical characteristics were identified from a prospective database. The cohort was separated into periods from 1992 through 2001 and 2002 through 2006 to identify longitudinal trends in risk factors for deep sternal wound infection. Univariate and matched multivariable analyses were performed. Results Overall, study population had in...

2010-01-01

86

Nutrition and Physical Activity in Aging, Obesity, and Cancer  

British Library Electronic Table of Contents (United Kingdom)

A wide variety of phytochemicals present in our diet, including fruits, vegetables, and spices, have been shown to possess a broad range of health-beneficial properties. The cytoprotective and restorative effects of dietary phytochemicals are likely to result from the modulation of several distinct cellular signal transduction pathways. Many dietary phytochemicals that are synthesized as secondary metabolites function as toxins, that is, -phytoalexins,- and hence protect plants against insects and other damaging organisms and stresses. However, at the relatively low doses consumed by humans and other mammals, these same toxic plant-derived chemicals, as mild stressors, activate adaptive cellular response signaling, conferring stress resistance and other health benefits. This phenomenon has...

2011-01-01

87

Effects of Sleep Apnea Severity on Glycemic Control in Patients with Type 2 Diabetes Prior to Continuous Positive Airway Presssure Treatment  

British Library Electronic Table of Contents (United Kingdom)

Abstract Background: Obstructive sleep apnea (OSA), a highly prevalent condition, is independently associated with increased risks of developing type 2 diabetes mellitus (T2D) and metabolic syndrome. It is unclear, however, if the severity of OSA has any impact on glycemic control among patients with T2D. We therefore aimed to determine the independent association between OSA severity and glycosylated hemoglobin (HbA1c) in patients with T2D. Methods: This was an observational cross-sectional study of 52 consecutive patients attending the diabetes obesity clinic between January 2008 to February 2010 with risk factors for sleep apnea and who underwent polysomnography study. Clinical, demographic, and lifestyle data were recorded using a questionnaire. Results: Prevalence of OSA in this clini...

2011-01-01

89

Mechanisms of obesity-induced male infertility  

British Library Electronic Table of Contents (United Kingdom)

Male infertility, characterized by hypogonadism, decreased semen quality or ejaculatory dysfunction, accounts for approximately 20% of infertility cases. Obesity and metabolic dysfunction have been identified, among other causal factors, to contribute to male infertility. In the context of the Western world's `obesity epidemic', this article discusses three main biological mechanisms linking obesity to impaired male reproductive function: hypogonadism, testicular heat stress/hypoxia-induced apoptosis and endocrine disruption by `obesogens'. Among these, obesity-induced hypogonadism is undoubtedly the most clinically significant and is easily assessed. Rapidly expanding areas of research in this area include leptin modulation of kisspeptins and hypothalamic-pituitary-testicular hormone path...

2010-01-01

90

The Role of Nutrition in the Etiology of Inflammatory Bowel Disease  

British Library Electronic Table of Contents (United Kingdom)

Many foods have been implicated in theories about the etiology of inflammatory bowel disease. While evidence has accumulated that nutritional factors as part of overall lifestyle changes may play a role in the growing incidence, no specific dietary recommendations except the promotion of breastfeeding can currently be given to decrease the risk of developing Crohn's disease or ulcerative colitis. For the treatment of Crohn's disease in children and adolescents, however, enteral feeding with a semi-elemental diet seems to be as effective as corticosteroids in inducing and maintaining remission. In the meta-analyses, advantages of one formula over the other are evened out, and more research is warranted into the anti-inflammatory properties of different nutrients, such as polyunsaturated fat...

2011-01-01

91

Fluoride rinsing and dental health inequalities in 11-year-old children: an evaluation of a supervised school-based fluoride rinsing programme in Edinburgh  

British Library Electronic Table of Contents (United Kingdom)

Levin KA, Jones CM, Wight C, Valentine C, Topping GVA, Naysmith R. Fluoride rinsing and dental health inequalities in 11-year-old children: an evaluation of a supervised school-based fluoride rinsing programme in Edinburgh. Community Dent Oral Epidemiol 2009; 37: 19-26. Copyright 2009 The Authors. Journal compilation Copyright 2009 John Wiley &Sons A/S Abstract - Objectives: Previous studies have shown that fluoride mouthrinsing programmes are effective in reducing caries among children and adolescents. National surveys of child dental health in the UK confirm that there is variation in oral health. In particular, children of low socioeconomic status in Scotland have a disproportionately high share of dental disease. This study aimed to evaluate an existing school-based fluoride mouthrinsi...

2009-01-01

92

Determination of radiation exposure and significance of its influential factors for X-rayed children in the GDR  

International Nuclear Information System (INIS)

After having discussed the peculiarities of children in X-ray diagnosis the application of the effective as well as the mean equivalent doses as to the determination of the radiation exposure in children is represented. In using computerized tomograms to determine position and extent of an organ the exposure by repeated X-raying was calculated referring to the entrance dose. Entrance dose measurements for all types of X-ray examination in hospitals and ascertainments of the frequency of radiograms in 20 X-ray departments were used to determine per capita and collective doses, resp., in several age groups. Alltogether, the per capita dose of children in the GDR amounts to 30% of that of adults. Conclusions were drawn as to taking measures to further reduction of radiation exposure: (1) Technical measures, such as positioning of patients, shielding of organs, quality assurance; (2) elaboration of regulations concerning the execution of X-raying in children and ...

1988-01-01

93

Effects of chronic ingestion of tritiated water on prenatal brain development  

International Nuclear Information System (INIS)

In view of the anticipated increased use of atomic energy in industry, the possible long-term effects of chronic radiation exposure were studied in five generations of rats. Female rats (F_0) were given tritiated drinking water ("3HOH;3#mu#Ci/ml) from adolescence (60 days) until and throughout pregnancy. A separate study showed that the maximum radioactivity in the urine is reached in 30 days, and in the blood in 42 days. In the newborns, the highest specific activity was in the nucleic acid fraction, but total radioactivity was mainly due to the water (body fluids) compartment. No signs of radiation illness or increase in cataract formation in the mothers were observed. The food and water intake and body weight changes before pregnancy were normal. The course and the outcome of pregnancy were also normal. However, 60% of the newborns (F_1) exhibited hematomas, edemas, and subdural hemorrhages, which disappeared at 30 days of age. Bollod ...

94

Effective per-capita dose as a yardstick for medical radiation exposure of the population - a supplement or an alternative to the genetically significant dose  

International Nuclear Information System (INIS)

The genetically significant dose (GSD) is an index variable which exclusively allows to describe the genetic risk in the progeny of a population due to the application of ionizing radiation and radioactive substances in one part of this population. It may result in wrong interpretation of population exposure at increasing incidence of examinations in a population involving ionizing radiation and radioactive drugs at simultaneously increasing application of alternative methods in children and adolescents owing to the fact that it indicates a downward trend although somatic exposure of this population has increased. Therefore, it is recommended to state both the GSD and the level of somatic radiation exposure of the population taken from the individual sources for the comparison and assessment of radiation exposure from various sources in future. Although the somatically significant dose constitutes the suitable variable complementary to GSD in thus context, it is ...

1984-06-01

95

Changes of serum leptin, adiponection and insulin levels in females with simple obesity  

International Nuclear Information System (INIS)

Objective: To study the changes of serum leptin, insulin and adiponectin levels and their relationship with BMI in females with simple obesity. Methods: Serum leptin, adiponectin and insulin levels were measured with RIA in 48 pre-obese females (BMI=23-24.9 kg/m"2), 40 females with simple obesity, (BMI#>=#25 kg/m"2) and 42 female controls (BMI 18-22.9 kg/m"2). Correlations among these variables were studied. Results: Serum leptin, insulin levels were significantly higher and serum adiponectin levels were significantly lower in both the pre-obese and obese females than those in controls. Serum leptin, insulin levels were positively correlated to BMI; Serum adiponectin levels were negatively correlated to BMI. Conclusion: Within normal range of BMI, the leptin-insulin feedback mechanism provided satisfactory self-regulation. However, with excessive BMI, this dynamic equilibrium ...

2004-08-01

96

Hypothalamic control of energy and glucose metabolism  

British Library Electronic Table of Contents (United Kingdom)

The central nervous system (CNS), generally accepted to regulate energy homeostasis, has been implicated in the metabolic perturbations that either cause or are associated with obesity. Normally, the CNS receives hormonal, metabolic, and neuronal input to assure adequate energy levels and maintain stable energy homeostasis. Recent evidence also supports that the CNS uses these same inputs to regulate glucose homeostasis and this aspect of CNS regulation also becomes impaired in the face of dietary-induced obesity. This review focuses on the literature surrounding hypothalamic regulation of energy and glucose homeostasis and discusses how dysregulation of this system may contribute to obesity and T2DM.

2011-01-01

97

Role of Obesity in Prostate Cancer Development  

Science.gov (United States)

... estrogen receptor status. Cancer Lett., 253, 291-300. 39. Xin,X ... and resistant mice. Brain Res.Bull., 52, 235-242. 40. Foster,BA ...

2011-04-01

98

If I Had - Morbid Obesity  

Medline Plus

... for a stapling or division of tissue the creation of a small gastric pouch which then assists ... follow up. Laparoscopic gastric bypass entails the surgical creation of a small gastric pouch, typically about an ...

99

Hormone-Sensitive Lipase Knockouts  

UK PubMed Central (United Kingdom)

All treatments for obesity, including dietary restriction of carbohydrates, have a goal of reducing the storage of fat in adipocytes. The chief enzyme responsible for the mobilization of FFA from adipose...Full Text Available

100

Honokiol enhances adipocyte differentiation by potentiating insulin signaling in 3T3-L1 preadipocytes  

British Library Electronic Table of Contents (United Kingdom)

Adipose tissue plays an essential role in energy homeostasis as a metabolic and endocrine organ. Accordingly, adipocytes are emerging as a major drug target for obesity and obesity-mediated metabolic syndrome. Dysfunction of enlarged adipocytes in obesity is involved in obesity-mediated metabolic syndrome. Adipocytokines, such as adiponectin released from small adipocytes, are able to prevent these disorders. In this study, we found that honokiol, an ingredient of Magnolia officinalis used in traditional Chinese and Japanese medicines, enhanced adipocyte differentiation in 3T3-L1 preadipocytes. Oil Red O staining showed that treatment with honokiol in the presence of insulin dose-dependently increased lipid accumulation in 3T3-L1 preadipoyctes although its activity was weak compared with r...

2011-01-01

101

Current Projects - Human Nutrition Research Center on Aging ...  

Science.gov (United States)

diet and genetic obesity metabolic defects and inflammation. To determine the role of adipocyte death in promoting adipose tissue inflammation and insulin resistance in animal...

2011-08-31

102

A molecular model for the genetic and phenotypic characteristics of the mouse lethal yellow (A{sup y}) mutation  

Energy Technology Data Exchange (ETDEWEB)

Lethal yellow (A{sup y}) is a mutation at the mouse agouti locus in chromosome 2 that causes a number of dominant pleiotropic effects, including a completely yellow coat color, obesity, an insulin-resistant type II diabetic condition, and an increased propensity to develop a variety of spontaneous and induced tumors. Additionally, homozygosity for A{sup y} results in preimplantation lethality, which terminates development by the blastocyst stage. The A{sup y} mutation is the result of a 170-kb deletion that removes all but the promoter and noncoding first exon of another gene called Raly, which lies in the same transcriptional orientation as agouti and maps 280 kb proximal to the 3{prime} end of the agouti gene. The authors present a model for the structure of the A{sub y} allele that can explain the dominant pleiotropic effects associated with this mutation, as well as the recessive lethality, which is unrelated to the ...

1994-03-29

103

Adolescent Morality: Social Responsibility versus Alienation. Unit for Child Studies. Selected Papers Number 26.  

Science.gov (United States)

Divided into three sections, this paper briefly presents Kohlberg's theory of moral reasoning; surveys some key research relating childrearing practices to adolescents' social competence, including moral reasoning; and reports research findings concerning the value systems adolescents develop. The first section characterizes preconventional, conventional, and postconventional morality and explores ways of promoting the development of a mature concept of justice, which includes role taking and living in a "just community." The second section focuses on aspects of social learning, which include authoritative parenting, inductive discipline, argumentative discourse, and tradition-based upbringing. In addition, this section explores socialization practices that hinder the development of mature moral reasoning. Focusing initially on characteristics of alienated youth and parental influences on such youth, the third section describes studies ...

1981-12-01

104

Pain catastrophizing scale for francophone adolescents: A preliminary validation  

UK PubMed Central (United Kingdom)

BACKGROUND:In adults, it is well known that high levels of pain catastrophizing are related to increased pain and disability as well as to heightened anxiety and depression. However,...Full Text Available

2008-01-01

105

Nonmedical use of opioid analgesics among Ontario students  

UK PubMed Central (United Kingdom)

ABSTRACTOBJECTIVETo explore the prevalence and the demographic predictors of nonmedical use of opioid analgesics in the Canadian adolescent population.DESIGNData...Full Text Available

2010-03-01

106

Lung carcinoma with hypertrophic osteoarthropathy in a teenager  

UK PubMed Central (United Kingdom)

Hypertrophic osteoarthropathy (HOA) characterised by arthralgia, clubbing and periosteal proliferation of long bones, is rarely encountered in children and adolescents. Whereas in adults over 80% of...Full Text Available

107

Glucose Intolerance and Cardiometabolic Risk in Adolescents Exposed to Maternal Gestational Diabetes  

UK PubMed Central (United Kingdom)

OBJECTIVEAdolescent offspring of women with a history of gestational diabetes (GD) were evaluated for their cardiometabolic risks at a mean age of 15 years.RESEARCH...Full Text Available

2010-06-01

108

Fronto-limbic Functioning in Children and Adolescents With and Without Autism  

UK PubMed Central (United Kingdom)

We used neuropsychological tasks to investigate integrity of brain circuits linking orbitofrontal cortex and amygdala (orbitofrontal-amygdala), and dorsolateral prefrontal cortex and hippocampus...Full Text Available

2008-01-15

109

Determinants of the drug utilization profile in the paediatric population in Italy's Lombardy Region  

UK PubMed Central (United Kingdom)

AIMSTo evaluate the intraregional differences in drug prescribing to children and adolescents.METHODSPrescriptions reimbursed...Full Text Available

2009-05-01

110

Stable isotope studies on iron bio-availability in young Indian women: Effects of nutritional status, interactions and ethnicity  

International Nuclear Information System (INIS)

Iron is an essential micronutrient. As an integral part of hemoglobin, it is essential for the transport of oxygen in blood to the tissues. It is an important component of cytochromes and other tissue enzymes that are critical for cellular respiration and of myoglobin that helps maintain oxygen reserve in the muscle. It is also involved in the normal functioning of the immune function, and in the synthesis of steroid hormones and bile acids. There are serious functional consequences to iron deficiency and iron deficiency anemia (IDA) in the human body. The deleterious effects include increased morbidity, preterm delivery, low birth weight, delayed cognitive development, lowered cellular immunity and reduced physical work capacity. However, iron deficiency and IDA remain the world's most common deficiency disease in the 21st century. Recent estimates of people affected with iron deficiency and IDA are 3.5 billion. Iron deficiency anemia is most prevalent and severe ...

2002-06-24

111

Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates  

International Nuclear Information System (INIS)

Acetylcholine and other neurotransmitters play unique trophic roles in brain development. Accordingly, drugs and environmental toxicants that promote or interfere with neurotransmitter function evoke neurodevelopmental abnormalities by disrupting the timing or intensity of neurotrophic actions. The current review discusses three exposure scenarios involving acetylcholine systems: nicotine from maternal smoking during pregnancy, exposure to environmental tobacco smoke (ETS), and exposure to the organophosphate insecticide, chlorpyrifos (CPF). All three have long-term, adverse effects on specific processes involved in brain cell replication and differentiation, synaptic development and function, and ultimately behavioral performance. Many of these effects can be traced to the sequence of cellular events surrounding the trophic role of acetylcholine acting on its specific cellular receptors and associated signaling cascades. However, for ...

2004-07-15

112

NAME=\\  

Wastenet

...INFORMATION Diarrhoeal disease Food safety and foodborne illness Enterohaemorrhagic Escherichia coli (EHEC) Cholera WHO PROGRAMMES AND ACTIVITIES Child and Adolescent Health and Development (...FOS) Initiative for Vaccine Research (IVR) TECHNICAL INFORMATION Vaccine research: diarrhoeal diseases Cholera Water-related diseases Household water treatment and safe storage WHO Global Salm-Surv ...PUBLICATIONS Diarrhoea: child and adolescent health Diarrhoea: cholera RELATED TOPICS - Child health - Water - Food safety - Cholera - Travel - Breastfeeding ...

113

Methylation similarities of two CpG sites within exon 5 of human H19 between normal tissues and testicular germ cell tumours of adolescents and adults, without correlation with allelic and total level of expression.  

UK PubMed Central (United Kingdom)

Testicular germ cell tumours (TGCTs) of adolescents and adults morphologically mimic different stages of embryogenesis. Established cell lines of these cancers are used as informative models to study...Full Text Available

1997-01-01

114

Bariatric surgery complications. Internal hernia: A potentially fatal condition. A case report and literature review  

International Nuclear Information System (INIS)

In recent years, Obesity (defined as Body Mass Index > 30 kg/m2) has increased its prevalence reaching epidemic levels in countries such as The United States where it has became a national health issue. In Colombia the Obesity prevalence is figured around 14%. Treatment options for Obesity include life style modifications, pharmacologist management and surgical approach (Bariatric Surgery). This article describes a patient with previous bariatric surgery, who presents abdominal pain and melena owed to isquemic process of the alimentary limb caused by an internal hernia which is a potentially lethal condition if it is not highly suspected allowing its early diagnosis and treatment

115

The Melanocortin 3 Receptor: A Novel Mediator of Exercise-Induced Inflammation Reduction in Postmenopausal Women?  

UK PubMed Central (United Kingdom)

The purpose of this study was to determine whether resistance exercise training-induced reductions in inflammation are mediated via melanocortin 3 receptor expression in obese (BMI 32.7 ± 3.7)...Full Text Available

116

Targeting the Pentose Phosphate Pathway in Syndrome X-related Cardiovascular Complications  

UK PubMed Central (United Kingdom)

Syndrome X is a combination or co-occurrence of several known cardiovascular risk factors (including central obesity, dyslipidemias, fatty liver disease, hyperinsulinemia, insulin resistance,...Full Text Available

2010-05-01

117

Severe Hypocalcemia due to Vitamin D Deficiency after Extended Roux-en-Y Gastric Bypass  

UK PubMed Central (United Kingdom)

Vitamin D deficiency is a well-known comorbidity of obesity that can be exacerbated after bariatric surgery and can predispose the patient for hypocalcemia. Vitamin D and calcium doses to prevent and...Full Text Available

2011-01-01

118

Role of histone methylation and demethylation in adipogenesis and obesity  

UK PubMed Central (United Kingdom)

Adipocyte differentiation is a complex developmental process that involves the coordinated interplay of numerous transcription factors. PPARγ has emerged as a master regulator of adipogenesis...Full Text Available

2010-01-01

119

Retrosternal Percutaneous Tracheostomy: An Approach for Predictably Impossible Classic Tracheostomy  

UK PubMed Central (United Kingdom)

Percutaneous tracheostomy is a routine procedure in intensive care units. In cases of very low position of the larynx, cervical spine deformation, morbid obesity, or neck tumor, performance of the classic...Full Text Available

2010-01-01

120

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex  

UK PubMed Central (United Kingdom)

Brown fat is a specialized tissue that can dissipate energy and counteract obesity through a pattern of gene expression that greatly increases mitochondrial content and uncoupled respiration. PRDM16...Full Text Available

2008-05-15

121

Rapid oscillations in omental lipolysis are independent of changing insulin levels in vivo  

UK PubMed Central (United Kingdom)

Abnormal fat metabolism plays an important role in the pathogenesis of obesity-related type 2 diabetes mellitus. This study examined whether free fatty acid levels (FFAs), like insulin levels, oscillate...Full Text Available

2000-08-01

122

Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons  

UK PubMed Central (United Kingdom)

Some pathological conditions with feeding pattern alterations, including obesity and Huntington disease (HD) are associated with hypothalamic dysfunction and neuronal cell death. Additionally, the hypothalamus...Full Text Available

123

Predictors of healthcare professionals' intention and behaviour to encourage physical activity in patients with cardiovascular risk factors  

UK PubMed Central (United Kingdom)

BackgroundHealthcare professionals can play a crucial role in optimizing the health status of patients with cardiovascular risk factors (abdominal obesity, high blood pressure, low...Full Text Available

124

Phylometabonomic Patterns of Adaptation to High Fat Diet Feeding in Inbred Mice  

UK PubMed Central (United Kingdom)

Insulin resistance plays a central role in type 2 diabetes and obesity, which develop as a consequence of genetic and environmental factors. Dietary changes including high fat diet (HFD) feeding promotes...Full Text Available

125

Pharmacological Stimulation of NADH Oxidation Ameliorates Obesity and Related Phenotypes in Mice  

UK PubMed Central (United Kingdom)

OBJECTIVENicotinamide adenine dinucleotides (NAD+ and NADH) play a crucial role in cellular energy metabolism, and a dysregulated NAD+-to-NADH ratio is implicated...Full Text Available

2009-04-01

126

Perceived Interpersonal Mistreatment Among Obese Americans: Do Race, Class, and Gender Matter?  

UK PubMed Central (United Kingdom)

Objective:We examine the extent to which body weight affects three types of perceived interpersonal mistreatment, and evaluate whether these patterns vary by race,...Full Text Available

2008-11-01

127

Neuronatin: A New Inflammation Gene Expressed on the Aortic Endothelium of Diabetic Mice  

UK PubMed Central (United Kingdom)

OBJECTIVE—Identification of arterial genes and pathways altered in obesity and diabetes.RESEARCH DESIGN AND METHODS—Aortic gene expression profiles of...Full Text Available

2008-10-01

128

Maternal Overweight Programs Insulin and Adiponectin Signaling in the Offspring  

UK PubMed Central (United Kingdom)

Gestational exposure to maternal overweight (OW) influences the risk of obesity in adult life. Male offspring from OW dams gain greater body weight and fat mass and develop insulin resistance when fed...Full Text Available

2010-06-01

129

Maternal Obesity Induced by Diet in Rats Permanently Influences Central Processes Regulating Food Intake in Offspring  

UK PubMed Central (United Kingdom)

Hypothalamic systems which regulate appetite may be permanently modified during early development. We have previously reported hyperphagia and increased adiposity in the adult offspring of rodents fed...Full Text Available

130

Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity  

UK PubMed Central (United Kingdom)

The mammalian circadian system consists of a central oscillator in the suprachiasmatic nucleus of the hypothalamus, which coordinates peripheral clocks in organs throughout the body. Although circadian...Full Text Available

2007-06-05

131

Individual differences and weight bias: Do people with an anti-fat bias have a pro-thin bias?  

Science.gov (United States)

While levels of weight bias vary among individuals, it is not clear why one person possesses stronger anti-fat attitudes than another person. This investigation examined whether individual differences commonly associated with greater anti-fat bias are also associated with a greater preference for thinness among people of varying levels of weight. Young adults (62% women; 84% Caucasian) recruited from psychology classes (N=308) rated four male and female figures with approximate BMIs of 18.5, 25, 30, and 40, on measures of dislike and personality characteristics and completed measures assessing weight controllability, attitudes toward the obese, and perceptual reliance. Greater negative attitudes, weight controllability beliefs, and perceptual reliance were positively associated with greater dislike and negative personality attributes among obese/severely obese figures, but inversely related among low normal weight figures. ...

2010-01-20

132

Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription  

UK PubMed Central (United Kingdom)

Cellular hypertrophy is regulated by coordinated pro- and antigrowth machineries. Foxo transcription factors initiate an atrophy-related gene program to counter hypertrophic growth. This study was designed...Full Text Available

2008-09-01

133

How Children Move: Activity Pattern Characteristics in Lean and Obese Chinese Children  

UK PubMed Central (United Kingdom)

Physical activity and sedentary behavior are central components of lifetime weight control; however, our understanding of dimensions of these behaviors in childhood is limited. This study investigated...Full Text Available

2011-01-01

134

Elevated BMI Is Associated With Decreased Blood Flow in the Prefrontal Cortex Using SPECT Imaging in Healthy Adults  

UK PubMed Central (United Kingdom)

Obesity is a risk factor for stroke and neurodegenerative disease. Excess body fat has been linked to impaired glucose metabolism, insulin resistance, and impulsivity and may be a precursor to decline...Full Text Available

2011-05-01

135

Efficacy of a meal replacement diet plan compared to a food-based diet plan after a period of weight loss and weight maintenance: a randomized controlled trial  

UK PubMed Central (United Kingdom)

BackgroundObesity has reached epidemic proportions in the United States. It is implicated in the development of a variety of chronic disease states and is associated with increased...Full Text Available

136

Dynamic body weight and body composition changes in response to subordination stress  

UK PubMed Central (United Kingdom)

Social stress is prevalent in many facets of modern society. Epidemiological data suggest that stress is linked to the development of overweight, obesity and metabolic disease. Although there...Full Text Available

2007-07-24

137

Deficiency of Phosphoinositide 3-Kinase Enhancer Protects Mice From Diet-Induced Obesity and Insulin Resistance  

UK PubMed Central (United Kingdom)

OBJECTIVEPhosphoinositide 3-kinase enhancer A (PIKE-A) is a proto-oncogene that promotes tumor growth and transformation by enhancing Akt activity. However, the physiological functions...Full Text Available

2010-04-01

138

Consumer purchasing patterns in response to calorie labeling legislation in New York City  

UK PubMed Central (United Kingdom)

BackgroundObesity is a major public health threat and policies aimed at curbing this epidemic are emerging. National calorie labeling legislation is forthcoming and requires rigorous...Full Text Available

139

Cathepsin K Null Mice Show Reduced Adiposity during the Rapid Accumulation of Fat Stores  

UK PubMed Central (United Kingdom)

Growing evidences indicate that proteases are implicated in adipogenesis and in the onset of obesity. We previously reported that the cysteine protease cathepsin K (ctsk) is overexpressed in the white...Full Text Available

140

Body Mass Index and Diabetes in Asia: A Cross-Sectional Pooled Analysis of 900,000 Individuals in the Asia Cohort Consortium  

UK PubMed Central (United Kingdom)

BackgroundThe occurrence of diabetes has greatly increased in low- and middle-income countries, particularly in Asia, as has the prevalence of overweight and obesity; in European-derived...Full Text Available

141

Beverage patterns and trends among school-aged children in the US, 1989-2008  

UK PubMed Central (United Kingdom)

BackgroundHigh intake of sugar-sweetened beverages in childhood is linked to increased risk of obesity and type II diabetes later in life. Using three nationally representative surveys...Full Text Available

142

Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats  

International Nuclear Information System (INIS)

Endocrine disrupting chemicals can induce malformations and impairment of reproductive function in experimental animals and may have similar effects in humans. Recently, the environmental obesogen hypothesis was proposed, suggesting that environmental chemicals contribute to the development of obesity and insulin resistance. These effects could be related to chemical interaction with nuclear receptors such as the peroxisome proliferator activated receptors (PPARs). As several testosterone-reducing drugs are PPAR activators, we aimed to examine whether four PPAR agonists were able to affect fetal testosterone production and masculinization of rats. Additionally, we wished to examine whether these chemicals affected fetal plasma levels of insulin and leptin, which play important roles in the developmental programming of the metabolic system. Pregnant Wistar rats were exposed from gestation day (GD) 7-21 to diisobutyl ...

2008-09-04

143

Youth-Family, Youth-School Relationship, and Depression  

UK PubMed Central (United Kingdom)

This study sought to examine the association between adolescents’ relationship with family and school and depressive symptoms across ethnic/racial groups (White, Black, Hispanic, and...Full Text Available

2010-04-01

144

Violent Victimization and Perpetration: Joint and Distinctive Implications for Adolescent Development  

UK PubMed Central (United Kingdom)

To date few reports have provided direct comparison of psychosocial vulnerability and resources among youth with victimization and perpetration histories. Within a racially diverse, high-risk...Full Text Available

2010-01-01

145

Substance use and dietary practices among students attending alternative high schools: results from a pilot study  

UK PubMed Central (United Kingdom)

BackgroundSubstance use and poor dietary practices are prevalent among adolescents. The purpose of this study was to examine frequency of substance use and associations between cigarette,...Full Text Available

146

Sleep and Fatigue Symptoms in Children and Adolescents With CKD: A Cross-sectional Analysis From the Chronic Kidney Disease in Children (CKiD) Study  

UK PubMed Central (United Kingdom)

BackgroundAlthough symptoms of sleepiness and fatigue are common among adults with Chronic Kidney Disease (CKD), little is known about the prevalence of these symptoms...Full Text Available

2010-02-01

147

Romantic and Sexual Relationships, Body Image, and Fertility in Adolescent and Young Adult Testicular Cancer Survivors: A Review of the Literature  

UK PubMed Central (United Kingdom)

This review presents a summary of existing knowledge regarding the impact of testicular cancer along four broad domains, including romantic and sexual relationships, body image, and fertility....Full Text Available

2010-08-01

148

Peer Group Self-Identification as a Predictor of Relational and Physical Aggression Among High School Students  

UK PubMed Central (United Kingdom)

BACKGROUNDAdolescent peer group self-identification refers to adolescents’ affiliation with reputation-based peer groups such as “Goths” or...Full Text Available

2010-05-01

149

Life Stress, Maternal Optimism, and Adolescent Competence in Single Mother, African American Families  

UK PubMed Central (United Kingdom)

Although research demonstrates many negative family outcomes associated with single-parent households, little is known about processes that lead to positive outcomes for these families. Using...Full Text Available

2010-08-01

150

Excessive TV viewing and cardiovascular disease risk factors in adolescents. The AVENA cross-sectional study  

UK PubMed Central (United Kingdom)

BackgroundExcessive television (TV) viewing might play an important role in the development of cardiovascular disease (CVD). The aim of this study was to examine the independent...Full Text Available

151

Comparison between children and adolescents with and without chronic benign pain: consultation rate and pain characteristics.  

UK PubMed Central (United Kingdom)

The aim of the study was to determine whether children with chronic benign pain are in contact with their general practitioner (GP) more frequently than those without chronic benign pain. A random sample...Full Text Available

2002-03-01

152

Coerced First Sex among Adolescent Girls in Sub-Saharan Africa: Prevalence and Context  

UK PubMed Central (United Kingdom)

Coercive experiences at sexual debut have been shown to be associated with other sexual risks throughout the life course. Using nationally representative surveys from 12–19 year old...Full Text Available

2007-01-01

153

Affective and Personality Risk and Cognitive Mediators of Initial Adolescent Alcohol Use*  

UK PubMed Central (United Kingdom)

Objective:This study examined the role of cognitive factors—such as expectancies regarding the consequences of not drinking and perceptions of peer drinking—in...Full Text Available

2010-07-01

154

A semi-qualitative study of attitudes to vaccinating adolescents against human papillomavirus without parental consent  

UK PubMed Central (United Kingdom)

BackgroundThe first vaccine to prevent human papillomavirus (HPV) and cervical cancer has been licensed, and in future, vaccination may be routinely offered to 10–14 year...Full Text Available

155

?-Opioid System Regulates the Long-Lasting Behavioral Adaptations Induced by Early-Life Exposure to Methylphenidate  

UK PubMed Central (United Kingdom)

Methylphenidate (MPH) is commonly prescribed in childhood and adolescence for the treatment of attention–deficit/hyperactivity disorders. In rodents, MPH exposure during preadolescence...Full Text Available

2009-04-01

156

Glutamate and the aggression neural circuit in adolescent anabolic steroid-treated Syrian hamsters (Mesocricetus auratus).  

Science.gov (United States)

Adolescent exposure to anabolic androgenic steroids (AAS) alters the development and activity of the glutamate neural system in the latero-anterior hypothalamus (LAH) in hamsters (Mesocricetus auratus); that is, an important neural component of the adolescent AAS-induced aggressive response. In this article, we used retrograde tracing to investigate glutamate-specific alterations in the connections between the LAH and several other nuclei implicated in adolescent AAS-induced aggression. Briefly, hamsters were treated with AAS or sesame-oil control during adolescence and then microinjected with retrograde tracer into the medial amygdala (MeA), lateral septum (LS), or bed nucleus of the stria terminalis (BNST). Brains were then processed for vesicular glutamate transporter 2 (VGLUT2) and examined for AAS-induced changes in the number VGLUT2 cells containing retrograde tracer (VGLUT2/tracer) within the ...

2011-08-22

157

Social modeling in the transmission of suicidality.  

Science.gov (United States)

Evidence from twin, adoption, and family studies suggests that there is strong aggregation of suicidal behaviors in some families. By comparison, the role of social modeling through peers has yet to be convincingly established. This paper uses data from four large studies (the WHO/EURO Multicentre Study on Suicidal Behaviour, the WHO/SUPRE-MISS, the CASE study, and the Queensland Suicide Register) to compare the effects of exposure to fatal and nonfatal suicidal behavior in family members and nonfamilial associates on the subsequent suicidal behavior of male and female respondents of different ages. Across all studies, we found that prior suicidal behaviors among respondents' social groups were more important predictors of suicidal behavior in the respondents themselves than previous research had indicated. Community-based suicide attempters in the WHO SUPRE-MISS had higher rates of exposure to prior suicide in nonfamilial associates than in family members. In an ...

2008-01-01

158

Long-term results following multidisciplinary treatment of localized Ewing's sarcoma in children and adolescents  

International Nuclear Information System (INIS)

Purpose: To identify results and prognostic factors on long-term survival and local control following treatment of localized Ewing's sarcoma. Patients and Methods: Between 1979 and 2004, a total of 60 children and young adults with Ewing's sarcoma were treated. Patients with distant metastases at presentation (n = 6) and recurrent cases (n = 2) were excluded from this analysis. Patients were exclusively treated within ongoing national and international protocols CESS-81, CESS-86, EICESS-92, EURO-EWING-99. All patients received local irradiation with a total dose of 45-60 Gy; in addition, 41 (79%) of the patients had local surgical procedures, 27 (52%) of them with clear margins. Results: Overall survival rates at 5 and 10 years were 56% and 45%, respectively. Patients #<=# 14 years at diagnosis had overall survival rates of 66% and 61% at 5 and 10 years compared to older patients with corresponding survival rates of 47% and 31%, respectively (p = 0.05). Patients with tumors of lower ...

2008-03-01

159

Inherited partial direct duplication of 11q: First report and possible association with a midline developmental field defect  

Energy Technology Data Exchange (ETDEWEB)

A 36-year-old woman underwent amniocentesis for advanced maternal age. The fetal karyotype had an extra dark staining G band on the long arm of chromosome 11 with no other identifiable abnormalities. FISH studies using a chromosome 11 paint probe confirmed the origin of the extra band. The abnormality was identified as a partial duplication of 11q: 46,XX dir dup (11)(q13.5q21) or (q21q23.1). The specific duplicated band could not be identified with certainty. Detailed fetal sonograms were normal. Family studies revealed the identical duplication in the mother but normal karyotypes in both maternal grandparents. The mother had strabismus and a short tongue frenulum which required surgical correction. Menses occurred late in adolescence and complete development of secondary sexual characteristics was delayed until adulthood. An infertility evaluation revealed duplication of the uterus, cervix, and vagina. An evaluation for metorrhagia identified a pituitary adenoma ...

1994-09-01

160

The relationship between periodontitis and metabolic syndrome among a Korean nationally representative sample of adults  

British Library Electronic Table of Contents (United Kingdom)

Abstract Aims: The aim of this study was to examine whether metabolic syndrome (MS) is associated with periodontitis in a representative sample of Korean adults, who were involved in the Fourth Korea National Health and Nutrition Examination Survey (KNHANES). Materials and Methods: A total of 7178 subjects over the age of 19 years who participated in KNHANES were examined. MS was defined as the definition proposed by the National Cholesterol Education Program Adult Treatment Panel III and the abdominal obesity cut-off line based on Korean Society for the Study of Obesity. The periodontal status was assessed by the Community Periodontal Index. Multivariate logistic regression analysis was carried out adjusting for the sociodemographics, oral health behaviours and status, and health behaviou...

2011-01-01

161

Green tea consumption, abdominal obesity as related factors of lacunar infarction in Korean women  

British Library Electronic Table of Contents (United Kingdom)

Objectives Our purpose was to evaluate interaction of green tea consumption and abdominal obesity as related factors for lacunar infarction in Korean women. Designs A hospital-based, incident case-control study. Settings The Prevention and Managements of Stroke in Women study. Participants Cases (n=233) of first incident lacunar infarction were enrolled and matched by age to stroke-free hospital controls (n=204). Measurements The data were collected through face-to-face interviews by well trained research assistants to assess demographic, medical, lifestyle, marital status, religions status, green tea consumptions, family history of stroke, smoking status, alcohol consumption, meat and vegetable intake frequency, and past history of hypertension. Biochemical analysis, fasting blood specime...

2011-01-01

162

Apelin, diabetes, and obesity  

British Library Electronic Table of Contents (United Kingdom)

Apelin is a peptide known as the ligand of the G-protein-coupled receptor APJ. Several active apelin forms exist such as apelin-36, apelin-17, apelin-13, and the pyroglutamated form of apelin-13. Apelin and APJ are expressed in the central nervous system, particularly in the hypothalamus and in many peripheral tissues. Apelin has been shown to be involved in the regulation of cardiovascular and fluid homeostasis, food intake, cell proliferation, and angiogenesis. In addition to be an ubiquitous peptide, apelin is also produced and secreted by adipocytes and thus considered as an adipokine. This has opened a new field of investigation establishing a link between apelin and metabolic disorders (obesity, type 2 diabetes, etc.) which is the focus of the present review. Several studies, but not...

2011-01-01

163

Comparison between children and adolescents with and without chronic benign pain: consultation rate and pain characteristics.  

Science.gov (United States)

The aim of the study was to determine whether children with chronic benign pain are in contact with their general practitioner (GP) more frequently than those without chronic benign pain. A random sample of children and adolescents aged between 0 and 18 years of age was drawn from the records of ten general practices. According to their responses to a pain questionnaire, subjects were assigned to the chronic benign pain group (n = 95) if they had pain of more than three months' duration, or to the control group (n = 105) if they had pain of less than three months' duration or no pain at all. All the subjects had an average GP consultation rate of 2.6 contacts per year. No significant age and sex differences were found. Chronic benign pain in childhood and adolescence is not related to increased use of healthcare services, suggesting that somatisation does not play a major role in children with chronic benign pain. PMID:12030664

2002-03-01

164

Two-year diagnostic stability in early-onset first-episode psychosis  

British Library Electronic Table of Contents (United Kingdom)

Background:- Only one study has used a prospective method to analyze the diagnostic stability of first psychotic episodes in children and adolescents. The Child and Adolescent First-Episode Psychosis Study (CAFEPS) is a 2-year, prospective longitudinal study of early-onset first episodes of psychosis (EO-FEP). Aim:- To describe diagnostic stability and the variables related to diagnostic changes. Methods:- Participants were 83 patients (aged 9-17-years) with an EO-FEP consecutively attended. They were assessed with a structured interview (Kiddie-Schedule for Affective Disorders and Schizophrenia, Present and Lifetime version) and clinical scales at baseline and after 2-years. Results:- The global consistency for all diagnoses was 63.9%. The small group of bipolar disorder had high stabilit...

2011-01-01

165

Sex determination using discriminant function analysis in children and adolescents: a lateral cephalometric study  

British Library Electronic Table of Contents (United Kingdom)

The objective of this study is to test the validity of sex determination in children and adolescents using lateral radiographic cephalometry and discriminant function analysis. Fifty male and 50 female cephalograms of Taiwanese children were used (males and females with mean age of 15.52???1.38 and 15.67???1.54?years, respectively). Twenty-two cephalometric measurements were performed using computerized cephalometry. Statistical analysis shows that all measurements were sexually dimorphic (p?

2010-01-01

166

Quantitative bone scintigraphy: follow-up of a femoral osteogenic sarcoma in an adolescent girl treated by chemotherapy and by massive allograft  

International Nuclear Information System (INIS)

Fifteen quantitative bone scintigraphies were performed in an adolescent girl during the follow-up of a femoral osteogenic sarcoma treated by chemotherapy and massive allograft. Three hours after injection of the radiopharmaceutical (7.4 MBq/kg of 99mTc-MDP) bone activity was measured in the inferior limbs at several regions of interest centered on the hips, femurs (proximal, middle, distal) and proximal tibias. The variations of relative bone activities A/S (ratio of corresponding counting rates between two homologous regions in the affected A and in the healthy S limb) and of absolute bone activities (expressed in counts/pixel-second) are interpreted as a function of times during treatment. The quantitative results are discussed with regard to main phenomena influencing bone activity in this particular clinical case: bone growth, chemotherapy and neo-osteogenesis in allograft.

167

Progressive neurostructural changes in adolescent and adult patients with bipolar disorder  

British Library Electronic Table of Contents (United Kingdom)

Lisy ME, Jarvis KB, DelBello MP, Mills NP, Weber WA, Fleck D, Strakowski SM, Adler CM. Progressive neurostructural changes in adolescent and adult patients with bipolar disorder.-Bipolar Disord 2011: 13: 396-405. 2011 The Authors.-Journal compilation 2011 John Wiley & Sons A/S. Objectives:- Several lines of evidence suggest that bipolar disorder is associated with progressive changes in gray matter volume (GMV), particularly in brain structures involved in emotional regulation and expression. The majority of these studies however, have been cross-sectional in nature. In this study we compared baseline and follow-up scans in groups of bipolar disorder and healthy subjects. We hypothesized bipolar disorder subjects would demonstrate significant GMV changes over time. Methods:- A total of 58 ...

2011-01-01

168

Non-formal basic education as a development priority: Evidence from Nicaragua  

British Library Electronic Table of Contents (United Kingdom)

Almost 900m adolescents and adults are illiterate in the developing world, yet most policy discussions focus on the educational circumstances of primary aged children. As a result non-formal educational programs for adolescents and adults are given very little support, and this group is virtually ignored in international agreements such as the millennium declaration. This article presents the first serious attempt at evaluating the impact of a non-formal education program. Results show significant learning achievement over the academic year, as well as strong development impacts of the program in non-learning dimensions of participants' lives. These positive impacts, plus the significantly lower unit costs and self-targeted nature of the program provide strong evidence that this type of pr...

2009-01-01

169

Behavioral Momentum during a Continuous Reading Task: An Exploratory Study  

Science.gov (United States)

Adolescents with emotional and behavioral disorders (EBD) often fail to master literacy skills, in part because disruptive behaviors interfere with task engagement and persistence. The theory of behavioral momentum explains the persistence of behavior in the face of changing environmental conditions. The current exploratory study examined variables related to behavioral momentum in the context of a continuous reading task. Participants were three adolescents identified with EBD who were instructional on fifth-grade material. Results indicated that when participants read a third-grade paragraph immediately before a fifth-grade paragraph, they decreased the latency to initiate reading of the fifth-grade paragraph and increased words read correctly per minute on the first 10 words of the fifth-grade paragraph. Results are discussed in terms of the theory of behavioral momentum and the nature of interventions that may be developed to increase ...

2011-09-01

170

Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation  

UK PubMed Central (United Kingdom)

BackgroundAdipokines, e.g. TNFα, IL-6 and leptin increase insulin resistance, and consequent hyperinsulinaemia influences breast cancer progression. Beside its mitogenic...Full Text Available

171

Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH  

UK PubMed Central (United Kingdom)

Increased oxidative stress is a known cause of cardiac dysfunction in animals and patients with diabetes, but the sources of reactive oxygen species [e.g., superoxide anion (O2)]...Full Text Available

2009-07-01

172

Silencing of Hepatic Fatty Acid Transporter Protein 5 in Vivo Reverses Diet-induced Non-alcoholic Fatty Liver Disease and Improves Hyperglycemia*S?  

UK PubMed Central (United Kingdom)

Non-alcoholic fatty liver disease is a serious health problem linked to obesity and type 2 diabetes. To investigate the biological outcome and therapeutic potential of hepatic fatty acid uptake inhibition,...Full Text Available

2008-08-08

173

Mice With a Deletion in the Gene for CCAAT/Enhancer-Binding Protein ? are Protected Against Diet-Induced Obesity  

UK PubMed Central (United Kingdom)

The CCAAT/enhancer-binding protein β (C/EBPβ) is required for adipocyte differentiation and maturation. We have studied the role of the transcription factor, C/EBPβ,...Full Text Available

2007-01-01

174

Relationships Between Level and Change in Family, School, and Peer Factors During Two Periods of Adolescence and Problem Behavior at Age 19  

UK PubMed Central (United Kingdom)

While prior research has examined family, school, and peer factors as potential predictors of problem behavior, less attention has been given to studying when these factors are most predictive...Full Text Available

2010-06-01

175

Insights in the use of health care services in chronic benign pain in childhood and adolescence.  

Science.gov (United States)

The utilization of health care services in children and adolescents with chronic benign pain was studied in a Dutch population sample of 254 chronic pain sufferers aged 0-18 years. Children and adolescents who had reported chronic pain (continuous or recurrent pain >3 months) in our previous prevalence study were asked to keep a 3-week diary on their pain and to fill out questionnaires on background factors, health care use and the impact of pain. Parent ratings were used for children aged 0-11 years, self-report was used in adolescents (12-18 years). In a 3-month period, in 53.4% of the cases medication was used for pain, and general practitioners and specialists were consulted for pain in 31.1% and 13.9% of subjects, respectively. Physiotherapists, psychologists and alternative health providers were visited by 11.5, 2.8, and 4.0%, respectively. In the preceding year, 6.4% had been hospitalized due to pain. The most ...

2001-11-01

176

Ewing's sarcoma in childhood and adolescence  

International Nuclear Information System (INIS)

A review of main issues in diagnosing, complex treatment and prognosis of Ewing's sarcoma is presented. Current trend in chemotherapy, radiotherapy and surgery of the disease is discussed. Unfavourable prognosis is attributed to the systematic character of the disease, necessitating a complex therapeutic approach. Attempts to make an optimal combination of the three therapeutic methods in order to improve survival and reduce the rate of post-treatment complications are analyzed. 37 refs., 4 tabs. (author).

177

The study of dual energy X-ray absorptiometry on body composition components in obesity  

International Nuclear Information System (INIS)

Objective: To study the correlation of the bone mineral density (BMD) and the body composition components of body mass index (BMI), FAT and LEAN in Chinese obesity. Methods: There were 150 cases in obesity group diagnosed by BMI, including 75 males [ median age 46 years, mean weight (89.64 #+-# 8.33) kg] and 75 females [median age 45 years, mean weight (77.23 #+-# 6.85) kg]. There were 150 persons with normal BMI in the control group, including 75 males [(median age 47 years, mean weight (62.34 #+-# 5.72) kg] and 75 females [ median age 45 years, mean weight (50.16 #+-# 5.06) kg]. The body height and weight of 300 persons in two groups were measured respectively and ,simultaneously calculated the BMI. These data and the body composition parameters measured by the dual energy X-ray absorptiometry (DEXA) in these two groups were compared and analyzed. The data obtained used two-sample t-test analysis, bi-variable correlation used Pearson linear ...

2009-06-01

178

An open-label study of naltrexone and bupropion combination therapy for smoking cessation in overweight and obese subjects  

British Library Electronic Table of Contents (United Kingdom)

A combination of sustained release (SR) naltrexone (32mg/day) and bupropion SR (360mg/day) plus behavioral counseling was evaluated for the treatment of smoking cessation and mitigation of nicotine withdrawal and weight gain. Thirty overweight or obese nicotine-dependent subjects were enrolled in a 24-week, open-label study; 85% and 63% completed 12 and 24weeks, respectively. The target quit date was Week 4. Week 4-12 continuous abstinence rate was 48%, 78% of subjects achieved CO 10ppm, serum cotinine decreased from 185 to 48mg/L, and tobacco use decreased from 129 to 14 cigarettes/week. Similar results were seen at Week 24. Body weight was essentially unchanged (Week 12: -0.1%; Week 24: +0.4%). Except for a transient significant increase 1week after the target quit date (p<0.05), nicotin...

2010-01-01

179

Nutrition and Physical Activity in Aging, Obesity, and Cancer  

British Library Electronic Table of Contents (United Kingdom)

The liver is a primary target of growth hormone (GH). GH signals are mediated by the transcription factor signal transducer and activator of transcription 5 (STAT5). Here, we focus on recent discoveries about the role of GH-STAT5 signaling in hepatic physiology and pathophysiology. We discuss roles of the GH-STAT5 axis in body growth, lipid metabolism, and the cell cycle pertaining to hepatosteatosis, fibrosis, and hepatocellular carcinoma. Finally, we discuss recent discoveries about the role of GH-STAT5 in sex-specific gene expression and bile acid, steroid, and drug metabolism.

2011-01-01

180

Human experience with an endoluminal, endoscopic, gastrojejunal bypass sleeve  

British Library Electronic Table of Contents (United Kingdom)

Background This report describes the authors? experience with a unique endoluminal, endoscopically delivered and retrieved gastroduodenojejunal bypass sleeve, including short-term weight loss and changes in comorbidities. Methods A prospective, single-center trial was designed. The patients were morbidly obese individuals who met the National Institutes of Health criteria for bariatric surgery. The device used was a unique gastroduodenojejunal bypass sleeve secured at the esophagogastric junction with endoscopic and laparoscopic techniques and designed to create an endoluminal gastroduodenojejunal bypass. At completion of the trial, the device was explanted with endoscopic retrieval. The primary end points were safety and incidence of adverse events. The secondary outcomes included the per...

2011-01-01

181

A research agenda to examine the efficacy and relevance of the Transtheoretical Model for physical activity behavior  

British Library Electronic Table of Contents (United Kingdom)

Regular physical activity (PA) decreases the risk of several chronic diseases including some cancers, type II diabetes, obesity, and cardiovascular disease; however, the majority of US adults are not meeting the recommended levels to experience these benefits. To address this public health concern, the underlying mechanisms for behavior change need to be understood, translated and disseminated into appropriately tailored interventions. The Transtheoretical Model (TTM) provides a framework for both the conceptualization and the measurement of behavior change, as well as facilitating promotion strategies that are individualized and easily adapted. The purpose of this manuscript is to present the constructs of the TTM as they relate to PA behavior change. We begin with a brief synopsis of rec...

2011-01-01

182

The relationships among bone health, insulin-like growth factor-1 and sex hormones in adolescent female athletes  

British Library Electronic Table of Contents (United Kingdom)

The aim of this study was to determine the relationships of bone mineral density (BMD) and content (BMC) with insulin-like growth factor-1 (IGF-1), IGF-binding protein-3 (IGFBP-3) and estradiol in pubertal female athletes. The participants were 170 healthy adolescent girls (13?15?years) who participated in competitive extramural athletic programs, i.e., sports games (n?=?49), track sprinting (n?=?24), rhythmic gymnastics (n?=?23), swimming (n?=?24) and cross-country skiing (n?=?17). The control group (n?=?33) consisted of girls who took part only in compulsory physical education classes at school. The whole-body BMD and femoral neck and lumbar spine BMD and BMC were measured using DXA, and the volumetric BMD was calculated. Venous blood samples to determine the concentration of IGF-1, IGFB...

2010-01-01

183

Home shrines in Britain and associated spiritual values  

British Library Electronic Table of Contents (United Kingdom)

In a quantitative survey of religious attitudes and practices in a multi-religious sample of 369 school pupils aged between 13 and 15 in London, the presence of a home shrine was found widespread in 11% of adolescents spanning several religious affiliations and ethnicities - especially Buddhists, Hindus and those of Indian, Chinese and 'Other Asian' ethnicity. Having a home shrine correlated significantly with spiritual attitudes such as agreement with filial piety, the Eightfold Path, subjectivity of happiness, meditation, Sikh festivals, reincarnation and opening Gurdwaras to all. It is suggested that teachers and the social services should be aware of the importance of shrines to many religious communities and recognise their potential as a spiritual asset and manifestation of religion ...

2010-01-01

184

Depression among Alumni of Foster Care: Decreasing Rates through Improvement of Experiences in Care  

Science.gov (United States)

The Northwest Foster Care Alumni Study examined the relation between experiences in foster care and depression among young adults who spent at least a year in foster care as adolescents. Results indicate that preparation for leaving foster care, nurturing supports from the foster family, school stability, access to tutoring, access to therapeutic service and support, and a shorter and more stable placement history were associated with a lower probability of depression in young adulthood. Results provide evidence that suggest ways to improve practice to decrease rates of depression among alumni of care. (Contains 2 tables.)

2008-12-01

185

The silent gallstone: Follow-up of 33 cases.  

Science.gov (United States)

This study reports the outcome of real-time ultrasonographic screening tests of a healthy population. The study group consisted of 33 female teachers who were found to have asymptomatic gallstone disease. All cases were followed up to determine the incidence of biliary colic or complications. After a 38-month period of follow-up, seven subjects (21.2%) developed either biliary colic or complication. Study results revealed that the 38-month cumulative probability of the development of biliary colic or complication was 36%. Data shown that development of biliary colic or complications was positively associated with obesity, but no assocition was found with age, number of activities, or duration of contraceptive pill-taking. Having such a high percentage of subjects who developed biliary colic or complications within a relatively short period of time suggests that the silent gallstone is not innocent. PMID:17372404

1996-03-01

186

Kundur [Benincasa hispida (Thunb.) Cogn.]: A potential source for valuable nutrients and functional foods  

British Library Electronic Table of Contents (United Kingdom)

Kundur [Benincasa hispida (Thunb.) Cogn.], a member of the family Cucurbitaceae, is one of the famous crops that are grown primarily for its fruits and usually recognized with its nutritional and medicinal properties especially in Asian countries. Kundur fruit has been valued as a nutritious vegetable as it provides a good source for natural sugars, amino acids, organic acids, mineral elements and vitamins. A number of medicinal properties such as anti-diarrheal, anti-obesity, anti-ulcer, and antioxidant and diuretic have been ascribed to this fruit of high economic value. As a rich source of functionally important bioactives and therapeutics such as triterpenes, phenolics, sterols, and glycosides, the fruit has been widely used for the treatment of epilepsy, ulcer, and other nervous disor...

2011-01-01

187

Generation and Characterization of Monoclonal Antibodies to Human Keratinocyte Growth Factor Receptor  

British Library Electronic Table of Contents (United Kingdom)

Keratinocyte growth factor receptor (KGFR) and fibroblast growth factor receptor (FGFR) 2c share identical amino acid sequences, except for a 46-amino acid domain in the extracellular region. Monoclonal antibodies (MAbs) specific to KGFR have not been reported nor are commercially available. In this study, we generated murine MAbs specific to KGFR in non-obese diabetic (NOD) mice using a modified Repeated Immunizations at Multiple Sites (RIMMS) technology. Stable cell lines expressing the full-length human KGFR or FGFR2c were produced to facilitate the identification of KGFR-specific MAbs. Following the initial screening of hybridoma clones with a fluorescence-based, confocal cell detection method and ELISA, KGFR-specific MAbs were selected and confirmed by flow cytometry and Western blot ...

2006-01-01

188

Young Cypriots' perspectives of the symbolic values of smoking  

British Library Electronic Table of Contents (United Kingdom)

This paper reports the findings of a study that explores the perspectives of 25 young Cypriots regarding the symbolic values of smoking with respect to their everyday lived experiences. This study was motivated by recognising the high levels of smoking prevalence among adolescents in Cyprus and the absence of published research 'recording' their own versions of reality about smoking. Data for the study were generated from one-to-one qualitative interviews which encouraged the participants to articulate the symbolic value of smoking in their day-to-day experiences. The analysis focuses first, on the content of the embedded symbolic values of smoking (e.g. the quality of being 'cool') and second on the role of these values (e.g. used in projecting an image) in their everyday lives. A central...

2010-01-01

189

Smoking and Aboriginal and Torres Strait Islander and Maori children  

British Library Electronic Table of Contents (United Kingdom)

Abstract Smoking and the deaths and suffering it causes are more common among Aboriginal and Torres Strait Islander peoples and Maori than other Australians and New Zealanders. While, many tobacco control activities that are not specifically targeted at children will have a positive impact on child health, this review concentrates on recent tobacco control research on pregnant women and children. The important tasks are to reduce smoking by pregnant Maori and Aboriginal and Torres Strait Islander women to reduce infant and child exposure to second-hand smoke and to reduce smoking initiation of children and adolescents. Health professionals who want to reduce the suffering caused by smoking among Maori and Aboriginal and Torres Strait Islander children can be guided by much new relevant res...

2010-01-01

190

Severe mood dysregulation: In the "light" of circadian functioning  

British Library Electronic Table of Contents (United Kingdom)

Severe affective and behavioral dysregulation, labeled as severe mood dysregulation (SMD), is a widely spread phenomenon among adolescent psychiatric patients. This phenotype constitutes severe impairment across multiple settings, including various symptoms, such as non-episodic anger, mood instability, and hyperarousal. Moreover, SMD patients often show depression and reduced need for sleep. Despite a lifetime prevalence of 3.3%, systematic research is still scarce, and treatments that have been established do not account for the range of symptoms present in SMD. Considering the circadian dysfunctions, two hormones, melatonin and cortisol, are essential. When these hormones are dysregulated, the circadian rhythm gets out of synchrony. Since evidence is emerging showing that the worse the ...

2011-01-01

191

Psychometric properties of a scale measuring negative attitudes toward overweight individuals.  

Science.gov (United States)

This study examined the psychometric properties of the Anti-fat Attitudes Scale (AFAS), a 5-item instrument developed by the authors to measure negative attitudes toward overweight individuals. A total of 4 studies were conducted among Canadian adolescents (n = 1,452) and university students (n = 424). Results suggested that the AFAS possessed a unidimensional factor structure and satisfactory reliability for both men and women. As predicted, men obtained higher scores than women on the AFAS, and antifat attitudes were positively associated with authoritarianism, homonegativity, and political conservatism. Participants who were overweight had lower scores on the AFAS than participants who were thin or average weight. Responses on the AFAS did not appear to be contaminated by social desirability bias. PMID:10457760

1999-08-01

192

One-year prospective follow-up of pharmacological treatment in children with attention-deficit/hyperactivity disorder  

British Library Electronic Table of Contents (United Kingdom)

Objectives To delineate the safety and tolerability profile of methylphenidate and atomoxetine in children and adolescents with attention deficit hyperactivity disorder (ADHD) monitored for more than 1?year. Design A cohort study analyzing data from the national ADHD register on patients from the Lombardy Region treated with MPH or atomoxetine. Participants A total of 229 children (median age 11?years, range 6?17), enrolled in 15 regional centers between June 2007 and May 2010. Results The prevalence rate of pharmacological treatment for ADHD was 0.23%, whereas the estimated ADHD prevalence in the population was 0.95%. In total, 73.8% of patients had been treated with atomoxetine (10?90?mg daily) or MPH (10?75?mg daily); 22% of patients also received an additional psychotropic drug. Of the...

2011-01-01

193

No association between affective and behavioral dysregulation and parameters of thyroid function in youths  

British Library Electronic Table of Contents (United Kingdom)

Objective: Evidence from adults suggests that changes in thyroid function are associated with the development of bipolar disorder (BD) and severe mood dysregulation. A dysregulation profile based on the Child Behavior Checklist (CBCL-DP) describes a phenotype with severe mood problems in youth. The present study investigated whether altered thyroid functioning in youths is associated with the severe mood dysregulation symptoms characterized by the CBCL-DP. Methods: We analyzed the thyroid function data from 262 children and adolescents (n=262 for serum TSH, n=148 for free triiodothyronine [fT3] and n=153 for free thyroxine [fT4]) with their CBCL-DP composite score. We created and compared high CBCL-DP and low CBCL-DP subgroups with regard to their serum TSH, fT3 and fT4 concentrations as w...

2011-01-01

194

Neurochemical deficits in the cerebellar vermis in child offspring of parents with bipolar disorder  

British Library Electronic Table of Contents (United Kingdom)

Singh MK, Spielman D, Libby A, Adams E, Acquaye T, Howe M, Kelley R, Reiss A, Chang KD. Neurochemical deficits in the cerebellar vermis in child offspring of parents with bipolar disorder.-Bipolar Disord 2011: 13: 189-197. 2011 The Authors.-Journal compilation 2011 John Wiley & Sons A/S. Objectives:- We aimed to compare concentrations of N-acetyl aspartate, myo-inositol, and other neurometabolites in the cerebellar vermis of offspring at risk for bipolar disorder (BD) and healthy controls to examine whether changes in these neuronal metabolite concentrations occur in at-risk offspring prior to the onset of mania. Methods:- A total of 22 children and adolescents aged 9-17-years with a familial risk for bipolar I or II disorder [at-risk offspring with non-bipolar I disorder mood symptoms (AR...

2011-01-01

195

Mode of Communication, Perceived Level of Understanding, and Perceived Quality of Life in Youth Who Are Deaf or Hard of Hearing  

British Library Electronic Table of Contents (United Kingdom)

Given the important role of parent-youth communication in adolescent well-being and quality of life, we sought to examine the relationship between specific communication variables and youth perceived quality of life in general and as a deaf or hard-of-hearing (DHH) individual. A convenience sample of 230 youth (mean age = 14.1, standard deviation = 2.2; 24% used sign only, 40% speech only, and 36% sign + speech) was surveyed on communication-related issues, generic and DHH-specific quality of life, and depression symptoms. Higher youth perception of their ability to understand parents' communication was significantly correlated with perceived quality of life as well as lower reported depressive symptoms and lower perceived stigma. Youth who use speech as their single mode of communication ...

2011-01-01

196

Mapping subcortical diffusivity. Application to brain development. Presidential award proceeding  

International Nuclear Information System (INIS)

We studied age-related microstructural changes in the subcortical white matter from adolescence to middle age in 16 healthy male subjects (age range: 12 to 47 years) using diffusion-weighted magnetic resonance (MR) imaging (DWI). Mean diffusivity (MD) of subcortical white matter was mapped onto the overlying cortical surface using our original method. The mean MD values within 76 cortical regions were measured using atlas-based gray matter segmentation and then correlated with age. A significant negative correlation with age was observed in subcortical MD values in several cortical regions, primarily over the bilateral temporal and occipital lobes. Our results demonstrated subcortical microstructural change in postadolescence that may reflect continuing myelination. (author)

2007-01-01

197

Investigation of cool and hot executive function in ODD/CD independently of ADHD  

British Library Electronic Table of Contents (United Kingdom)

Background:- Children with oppositional defiant disorder/conduct disorder (ODD/CD) have shown deficits in -cool- abstract-cognitive, and -hot- reward-related executive function (EF) tasks. However, it is currently unclear to what extent ODD/CD is associated with neuropsychological deficits, independently of attention deficit hyperactivity disorder (ADHD). Methods:- Fifty-nine adolescents with a history of early-onset oppositional problems, 28 with pure ODD/CD symptoms and 31 with ADHD with or without ODD/CD, and 34 healthy controls were administered a task battery measuring motor response inhibition, sustained attention, cognitive flexibility and reward-related decision-making. Findings were analysed using dimensional and group analyses. Results:- In group analyses both groups with and wit...

2011-01-01

198

Early diagnosis of skeletal disorders in childhood and adolescence by MRI; Fruehdiagnose orthopaedischer Erkrankungen des Kindes- und Jugendalters mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

The early diagnosis of such disorders is of major importance because, in most cases, severe consequences can only be averted by early treatment. The value of magnetic resonance imaging (MRI) in many orthopaedic and traumatological conditions is generally accepted. The value of MRI in this particular field is illustrated by typical case reports on common clinical problems [Deutsch] Der Fruehdiagnose von Erkrankungen des Kindes- und Jugendalters kommt grosse Bedeutung zu, da oftmals nur durch eine daraus resultierende Fruehbehandlung schwerwiegende Folgen vermieden werden koennen. Die Kernspintomographie (Magnetresonanztomographie=MRT) ist in zahlreichen orthopaedischen-traumatologischen Fragestellungen bereits etabliert. An ausgewaehlten Fallbeispielen haeufiger klinischer Problemstellungen soll in der vorliegenden Arbeit der Stellenwert der MRT dargestellt werden. (orig.)

1998-09-18

199

Dimensions and Latent Classes of Episodic Mania-Like Symptoms in Youth: An Empirical Enquiry  

British Library Electronic Table of Contents (United Kingdom)

The dramatic increase in diagnostic rates of bipolar disorder in children and adolescents in the USA has led to an intense interest in the phenomenology of the disorder. Here we present data from a newly-developed instrument to assess episodic mania-like symptoms in youth in a large population-based sample (N?=?5326) using parent- and self-report. We found that a substantial proportion of children screened positive for having episodes of ?going high? and were at an increased risk for morbidity and impairment. Using factor analysis, we identified that episodic mania-like symptoms comprised two dimensions: An under-controlled dimension that was associated with significant impairment, and a low-risk exuberant dimension. Using latent class analysis, we identified a small group of children scor...

2011-01-01

200

Bipolar Disorder in Children and Adolescents Recognised in the UK: A Clinic-Based Study  

British Library Electronic Table of Contents (United Kingdom)

Background:- Diagnoses of paediatric bipolar disorder have increased over the last two decades in the United States, where high levels of comorbidity with ADHD have also been reported. Aims:- To explore how British clinicians apply these diagnoses. Method:- We compared 378 young people under the age of 18 who received a diagnosis of bipolar disorder and/or ADHD from a large NHS mental health trust between 1992 and 2007. Results:- Children with bipolar disorder were rare in this sample (n-=-35, 1.0%), particularly under the age of 13 (n-=-9, 0.3%). Children with bipolar disorder presented more often with affective and psychotic symptoms than children with ADHD. Irritability was common in both disorders. Core ADHD symptoms were prevalent in both conditions but occurred in a greater proportio...

2011-01-01

201

A PAC containing the human mitochondrial DNA polymerase gamma gene (POLG) maps to chromosome 15q25  

Energy Technology Data Exchange (ETDEWEB)

The human mitochondrial DNA (mtDNA) is a closed circular, 16,569-bp double-stranded DNA, encoding 13 genes whose protein products are subunits of the oxidative phosphorylation system required for synthesis of most of the ATP consumed by eukaryotic cells. Point mutations of the mtDNA that cause multi-tissue, loss-of-energy syndromes, called mitochondrial encephalomyopathies (e.g., MERRF and MELAS), have been identified. In addition, large-scale deletions of the human mtDNA have been identified and are the molecular bases for the neonatal and adolescent onset loss-of-energy syndromes Pearson and Kearns-Sayer, respectively. 5 refs., 1 fig.

1997-03-01

202

Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes.  

Science.gov (United States)

Elevated fatty acid levels have been thought to contribute to insulin resistance. Repression of the glucose transporter 4 (GLUT4) gene as well as impaired GLUT4 translocation may be a mediator for fatty acid-induced insulin resistance. This study was initiated to determine whether palmitate treatment repressed GLUT4 expression, whether glucose/fatty acid metabolism influenced palmitate-induced GLUT4 gene repression (PIGR), and whether attempts to prevent PIGR restored palmitate-induced impairment of glucose uptake (PIIGU) in C2 myotubes. Not only stimulators of fatty acid oxidation, such as bezafibrate, AICAR, and TOFA, but also TCA cycle substrates, such as pyruvate, leucine/glutamine, and ?-ketoisocaproate/monomethyl succinate, significantly prevented PIGR. In particular, supplementing with pyruvate through methyl pyruvate resulted in nearly complete prevention of PIIGU, whereas palmitate treatment reduced the intracellular pyruvate level. These results suggest that pyruvate ...

2011-07-23

203

Function-preserving surgery for rectal cancer  

International Nuclear Information System (INIS)

When total mesorectal excision (TME) is accurately performed, dysfunction, theoretically, does not occur. However, there are differences among individuals in the running patterns and the volumes of nerve fibers, and if obesity or a narrow pelvis is present, nerve identification is difficult. Currently, the rate of urinary dysfunction after rectal surgery ranges from 33% to 70%. Many factors other than nerve preservation play a role in minor incontinence. Male sexual function shows impotence rates ranging from 20% to 46%, while 20%-60% of potent patients are unable to ejaculate. In women, information on sexual function is not easily obtained, and there are more unknown aspects than in men. As urinary, sexual, and defecation dysfunction due to adjuvant radiotherapy have been reported to occur at a high frequency, the creation of a protocol that enables analysis of long-term functional outcome will be essential for future clinical trials. In the treatment of rectal ...

2006-10-01

204

Some mechanical properties of goose femoral cortical bone.  

Science.gov (United States)

The ultimate compressive strength and modulus of elasticity of femoral cortical bone from adult geese (Anser anser), were determined by sex and by quadrant by compressing small right circular cylinders which were 2.4 mm in height and 0.8 mm in diameter. The average ultimate compressive strength was 183 +/- 29 MPa. The average modulus of elasticity was 13.2 +/- 3.4 GPa. The bending strength and bending modulus of elasticity were determined by a three point bend test on rectangular prisms which had the approximate dimensions 0.75 mm X 0.75 mm X 25 mm. The average bending strength was 263 +/- 44 MPa while the average bending modulus was 19.6 +/- 3.1 GPa. The calcium content was determined by atomic absorption spectrophotometry and no correlation was found with the mechanical properties. The histology of the cortical bone was examined both quantitatively and qualitatively. A unique type of Haversian bone is described. Goose bone was found to be morphologically similar to ...

1983-01-01

205

Herlyn-Werner-Wunderlich syndrome: uterus didelphys, blind hemivagina and ipsilateral renal agenesis. Sonographic and MR findings in 11 cases  

Energy Technology Data Exchange (ETDEWEB)

Uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis is a rare entity, sometimes referred to as Herlyn-Werner-Wunderlich syndrome (HWW). It usually presents after menarche with progressive pelvic pain, sometimes with regular menses, and a palpable mass due to hemihaematocolpos. The diagnosis is generally made only if the suspicion of this genitourinary syndrome is raised. To highlight the imaging diagnostic clues in this rare condition. We report on 11 adolescents with this condition. Sonography mostly allowed the correct diagnosis by showing uterovaginal duplication, haematocolpos or haematometrocolpos, and the absence of the ipsilateral kidney. MRI provided more detailed information regarding uterine morphology, the continuity with each vaginal channel (obstructed and nonobstructed), and the bloody nature of the contents. Early and accurate diagnosis of this syndrome is important so that adequate and prompt surgical therapy (excision of the ...

2007-07-15

206

Fast quantitative diffusion-tensor imaging of cerebral white matter from the neonatal period to adolescence  

International Nuclear Information System (INIS)

We investigated the isotropic diffusion coefficient (D') and fractional anisotropy (FA) in white matter (WM) during brain development, using an optimised diffusion-tensor imaging (DTI) method with whole brain coverage in a clinically acceptable time. We images 52 children with no evident neurological abnormality (30 boys, 22 girls aged 1 day-16 years) using high-angle DTI with optimised temporal gradient performance. D' and FA were calculated in 10 regions of interest in white matter. We saw that the age-related reduction in D' and increase in FA follow a mono- or biexponential model in white matter, probably depending on the compactness and myelination rate of the fibre tracts. In contrast to other areas, in which adult values were reached during the third year, there is a trend to continuous increase in FA in all deep white-matter areas, suggesting continuing maturation and organisation of deep tracts not detected on conventional MRI. (orig.)

2004-04-01

207

New approach for in vivo detection of insulitis in type I diabetes: activated lymphocyte targeting with "1"2"3I-labelled interleukin 2  

International Nuclear Information System (INIS)

Insulitis is considered the histopathological hallmark of type I diabetes. In the non-obese diabetic (NOD) mouse, diabetes has never been observed in the absence of insulitis. The in vivo detection of insulitis could be of relevance for early prediction of diabetes. As approximately 15% of islet-infiltrating lymphocytes express interleukin 2 receptors, the authors have labelled recombinant inter-leukin 2 with "1"2"3I and used this radiopharmaceutical to detect insulitis by gamma camera imaging. The authors studied 71 prediabetic NOD and 27 normal Balb/c mice. Labelled #alpha#-lactalbumin was used as the control protein. In the first set of experiments the tissue distribution of radiolabelled interleukin 2 in isolated organs from animals sacrificed at different time points was studied. Higher radioactivity was detected in the pancreas of NOD mice injected with labelled interleukin 2, as compared to NOD mice receiving labelled #alpha#-lactalbumin. In another set of ...

1994-01-01

208

Primary spinal epidural extraosseous Ewing's sarcoma: Report of five cases and literature review  

International Nuclear Information System (INIS)

Ewing's sarcoma is the most common malignant bone tumour occurring in children and adolescents and exists in two different clinico pathological entities: osseous Ewing's sarcoma (OES) and extraosseous Ewing's sarcoma (EES). Five cases of primary epidural EES are described, which presented with non-specific symptoms leading to a long diagnostic delay. The median age at diagnosis was 22 years (range 13-36 years). The median diagnostic delay was 3 months. All patients had one or more neurological deficits. All underwent surgical exploration with a laminectomy and partial resection followed by adjuvant radiotherapy to a dose of 46-50 Gy and chemotherapy with VAC (vincristine, adriamycin and cyclophosphamide) alternating with ICE (ifosphamide, cisplatin and etoposide) for at least six cycles. The mean follow-up period is 21.2 months (range 11-32 months). Four of the five patients achieved a complete remission and are disease free at the time of writing this report. Two ...

2001-08-01

209

Liver volume in thalassaemia major: relationship with body weight, serum ferritin, and liver function  

Energy Technology Data Exchange (ETDEWEB)

It is not known whether body weight alone can adjust for the volume of liver in the calculation of the chelating dose in {beta}-thalassaemia major patients, who frequently have iron overload and hepatitis. The hypothesis is that liver volume in children and adolescents suffering from {beta}-thalassaemia major is affected by ferritin level and liver function. Thirty-five {beta}-thalassaemia major patients aged 7-18 years and 35 age- and sex-matched controls had liver volume measured by MRI. Serum alanine aminotransferase (ALT) and ferritin levels were obtained in the thalassaemia major patients. Body weight explained 65 and 86% of the change in liver volume in {beta}-thalassaemia major patients and age-matched control subjects, respectively. Liver volume/kilogram body weight was significantly higher (P<0.001) in thalassaemia major patients than in control subjects. There was a significant correlation between ALT level and liver volume/kilogram body weight ...

2005-02-01

210

Diagnosis and treatment of Ewing's sarcoma  

International Nuclear Information System (INIS)

Ewing's sarcoma is a small round-cell tumor typically arising in the bones, rarely in soft tissues, of children and adolescents. Ewing's sarcoma has retained the most unfavorable prognosis of all primary musculoskeletal tumors. Prior to the use of multi-drug chemotherapy, long-term survival was less than 10%. The development of multi-disciplinary therapy with chemotherapy, irradiation, and surgery has increased current long-term survival rates in most clinical centers to greater than 50%. In addition, the preferred method of tumor resection has changed; limb salvage has nearly replaced amputation of the affected limb. Limb salvage procedures can be performed in place of amputation without compromising patient survival rates. Recent studies have revealed that the pathognomonic translocations involving the EWS gene on chromosome 22 and an ETS-type gene, which is most commonly the Fli1 gene on chromosome 11, are implicated in more than 95% of Ewing's sarcomas, ...

2007-02-01

211

Cytopathic Effects of Viruses Protocols  

Science.gov (United States)

Protocols for using Cytopathic Effects of Viruses

2007-09-29

212

Primary Ewing's sarcoma of the vertebral column  

International Nuclear Information System (INIS)

To determine the demographics, imaging findings, clinical symptoms, and prognosis of primary vertebral Ewing's sarcoma (PVES). A retrospective review of medical records and radiological studies of patients diagnosed with PVES from 1936 through 2001 in our institution and Department of Pathology consultation files was undertaken. Metastatic and soft tissue Ewing's sarcoma cases were excluded. From a total of 1,277 cases of Ewing's sarcoma, 125 (9.8%) had a primary vertebral origin. There were 48 females and 76 males. Patient ages ranged from 4 to 54 (mean 19.3, standard deviation 10.7, median 16) years. Vertebral column distribution was four cervical (3.2%), 13 thoracic (10.5%), 31 lumbar (25%), and 67 sacrum (53.2%). More than one vertebral segment was involved in ten cases (8%). Satisfactory imaging studies were available in 51 patients: 49 radiographs, 27 computerized tomography (CT), and 23 magnetic resonance imaging (MRI) studies. The majority of tumors were lytic (93%). Three ...

2004-09-01

213

Clinically silent heterotaxy with polysplenia syndrome and IVC azygous continuation draining to SVC: CT findings. Case report  

International Nuclear Information System (INIS)

Patients with heterotaxy syndrome often have complex cardiac and extracardiac anomalies requiring further detailed diagnostic evaluation. They often present severe cardiac failure early in life. Newer radiological modalities in the form of spiral computed tomography (CT) and three-dimensional reconstruction of spiral CT allow clear definition of the anatomy of these anomalies. A 59-year-old woman was diagnosed with polysplenia and multiple anomalies in an abdominal ultrasonography (US) during a control medical examination due to a trivial dietary mistake. She was then referred to our institution for further examination of these anomalies and an additional thoraco-abdominal computed tomography (CT) examination. The patient was totally asymptomatic at the time of admission. There was no significant past history and no abnormal laboratory data. We performed abdominal, pelvic and thoracic CT examinations using Somatom Siemens Emotion scanner. Non-enhanced sections were obtained with 8 mm ...

2007-01-01

214

Effect of Pressures up to 2.0 GPa on the Mechanical ...  

Science.gov (United States)

... hydrostatic pressures up to 700 MPa. The effect of pressure on the ultimate compressive strength is shown. The effect of size on ...

219

Effects and side-effects of integrating care: the case of mental health care in the Netherlands  

UK PubMed Central (United Kingdom)

PurposeDescription and analysis of the effects and side-effects of integrated mental health care in the Netherlands.Context of caseDue...Full Text Available

220

Solar wind effect on the muon flux at sea level  

CERN Document Server

Solar wind effect on the muon flux at sea level

2005-01-01

221

New Effective Pesticides  

International Science & Technology Center (ISTC)

Development the New Effective Pesticides in the Series of Pyrimine and Sym-Triazine Derivatives

222

The Effect of Morpholine/Boric Acid/Hydrazine Chemistry on ...  

Science.gov (United States)

... the effect of MBH on steam generator crevice corrosion; model boiler test results show that MBH is effective against denting corrosion and Alloy 600 ...

223

Electromagnetic Effects Requirements for Systems.  

Science.gov (United States)

This standard establishes requirements, verification criteria, and contractor tasks for electromagnetic effects protection of airborne, ground, and support systems. These effects include electromagnetic compatibility, electromagnetic interference, lightni...

1993-01-01

233
263

The effects of organosulfur compounds upon the storage stability of Jet A fuel  

Science.gov (United States)

This study examined the effect of sulfur-containing compounds on the storage stability of Jet A

1981-01-01

264

The Effects of Flame Retardant Combinations in PVC ...  

Science.gov (United States)

... Title : The Effects of Flame Retardant Combinations in PVC-Epoxidised Natural Rubber Miscible Blends: Antimony Trioxide in Combination with ...

1989-03-01

265

The Effect of the Temperature to Which the Material is Heated ...  

Science.gov (United States)

... The Effect of the Temperature to Which the Material is Heated on the Process of Formation of Intermetallic Compounds in Magnetic Pulse Welding,. ...

1980-09-01

266

Heavy Metals Effect on Animal Cells  

International Science & Technology Center (ISTC)

Studies of the Superheavy-metal Effect as a Stress-factor on Protein Biosynthesis and Cytoskeleton Integrity in Animal Cells

267

Effects of Pentobarbital Anesthesia on Survival, 'Escherichia ...  

Science.gov (United States)

... Title : Effects of Pentobarbital Anesthesia on Survival, 'Escherichia coli' Clearance, Glucose and Leukocyte Concentration in Dogs Subjected to ...

1978-08-28

268

Effect of dietary constituents on the absorption of lead in the human  

International Nuclear Information System (INIS)

... biological effects body burden diet intestinal absorption lead lead 203 man

1983-03-01

269

Effect of Yttrium on the Microstructure of Titanium Alloys,  

Science.gov (United States)

... Title : Effect of Yttrium on the Microstructure of Titanium Alloys,. ... The yttrium was added in the melting stage as an oxide or in the elemental form. ...

270

EFFECTS OF SHIELDING ON PROPERTIES OF EDDY ...  

Science.gov (United States)

... Accession Number : ADD323869. Title : EFFECTS OF SHIELDING ON PROPERTIES OF EDDY CURRENT PROBES WITH FERRITE CUP CORES. ...

1986-08-01

271

Diaphragm Rupture Effects on an Expanding Flow in a Tube.  

Science.gov (United States)

... The fundamental problem of diaphragm rupture was studied experimentally to determine the effects on an expanding flow in an evacuated tube. ...

1972-08-01

272

Coherency Effects on Retinal Neural Processes (ERG) of ...  

Science.gov (United States)

... Accession Number : ADA111683. Title : Coherency Effects on Retinal Neural Processes (ERG) of Pseudemys. Descriptive ...

1981-12-01

273

Learning Effect and Standardization Effect in NPP's Construction  

International Nuclear Information System (INIS)

This paper describes the learning effect and standardization effect in the nuclear power construction, analyses their influence degree on nuclear power economics. Furthermore, the paper provides the ideas on how to improve the economics of nuclear power through implementing the learning effect and standardization effect. The paper also concludes that the learning rate in China is better than the average value in the world by analysis actual example. (authors)

2009-09-01

274

Effective medium theory of the one-dimensional resonance phononic crystal  

International Nuclear Information System (INIS)

A general theoretical scheme to describe the effective modulus and mass density for acoustic metamaterials is presented. For such a purpose, an effective medium theory of a one-dimensional acoustic waveguide containing subwavelength-sized Helmholtz resonators is formulated. It is shown that, when the wavelength is much larger than the periodic length and the size of the resonators, the whole composite structure can be treated as an effective homogeneous medium in accounting for its acoustic properties. It is also shown that the acoustic characteristics, such as the effective modulus and the effective mass density, can be determined precisely from the transmission and the reflection data. The calculated effective modulus and effective mass density confirm that this structure behaves as a homogeneous metamaterial with a negative ...

2008-02-06

275

Physical mechanism in the free-electron laser  

International Nuclear Information System (INIS)

In this paper some physical mechanisms are described, which determine some new free-electron laser configurations. These mechanisms comprise some physical effects of the radiant emission of an electron beam at the interaction with the medium it is crossing. They are based on the Cherenkov effect, Smith-Purcell effect, optical klystron, Rumakhov effect and limited interaction effect. (Author).

1992-09-21

276

Ionising radiation. Part 2  

Energy Technology Data Exchange (ETDEWEB)

A brief tutorial on the health effects of ionising radiation is presented. The distinction between somatic and genetic health effects is explained. The two types of somatic health effects, i.e., acute and chronic effects, are discussed, as well as the concepts of ''deterministic'' and ''stochastic'' (also called ''probabilistic'') health effects. The possibility of cancer caused by DNA damage is discussed. The document ends with the definition of some key radiation terms.

2000-11-01

277

Effects of gamma irradiation on physiological effectiveness of Korean medicinal herbs  

Energy Technology Data Exchange (ETDEWEB)

Effects of gamma irradiation on the physiological effectiveness of Korean medicinal herbs were investigated. The physiological effectiveness including antioxidant and anticomplement function, nitrite scavenging and electron donating ability of Korean medicinal herbs by gamma irradiation at 10 kGy did not differ from that of the nonirradiated control.

1999-03-01

278

The effects of exercise and stress on the survival and maturation of adult-generated granule cells  

UK PubMed Central (United Kingdom)

Stress strongly inhibits proliferation of granule cell precursors in the dentate gyrus, while voluntary running has the opposite effect. Few studies, however, have examined the possible effects...Full Text Available

2009-10-01

279

TJ-41 Induces Apoptosis and Potentiates the Apoptotic Effects of 5-FU in Breast Cancer Cell Lines  

UK PubMed Central (United Kingdom)

Recent studies suggest that TJ-41, a herbal drug, possesses chemotherapeutic effects. Accordingly, this study was undertaken to investigate the anticarcinogenic effects of TJ-41 on human breast cancer...Full Text Available

2009-01-01

280

Mouse model predicts effects of smoking and varenicline on event-related potentials in humans  

UK PubMed Central (United Kingdom)

Background:Nicotine alters auditory event-related potentials (ERPs) in rodents and humans and is an effective treatment for smoking cessation. Less is known about the effects of...Full Text Available

2010-06-01

281

Memory effect in air in the presence of vacuum breakdown mechanism  

Science.gov (United States)

Investigation of memory effects in air at 0.7 mbar pressure in the presence of vacuum electrical breakdown mechanism has been performed in this paper. The memory effect has been followed using the time delay method.

2008-07-01

282

Health effects of urea formaldehyde foam insulation: evidence of causation.  

UK PubMed Central (United Kingdom)

Studies of health effects of urea formaldehyde foam insulation (UFFI) were critically reviewed by means of accepted rules for evidence of causation. Three categories of health effects were examined:...Full Text Available

1986-04-01

283

Epidemiological survey of the effects of low level radiation dose: a comparative assessment  

Energy Technology Data Exchange (ETDEWEB)

This volume presents the collations tables of a six volume comparative epidemiological survey of the effects of low level radiation dose. Data are collated for the effects observed in the following irradiated groups:- Preconception irradiation, intra-uterine irradiation, childhood irradiation, adult irradiation. (UK).

1993-10-01

284

Effects of calcium supplementation on bone density in healthy children: meta-analysis of randomised controlled trials  

UK PubMed Central (United Kingdom)

Objectives To assess the effectiveness of calcium supplementation for improving bone mineral density in healthy children and to determine if any effect is modified by other factors and...Full Text Available

2006-10-14

285

Cost-Effectiveness of an Opportunistic Screening Programme and Brief Intervention for Excessive Alcohol Use in Primary Care  

UK PubMed Central (United Kingdom)

BackgroundEffective prevention of excessive alcohol use has the potential to reduce the public burden of disease considerably. We investigated the cost-effectiveness of Screening...Full Text Available

286

Cost-Effectiveness Analysis of Proposed Effluent Limitations Guidelines and Standards for the Metal Products and Machinery Industry (Phase 1).  

Science.gov (United States)

This cost-effectiveness analysis supports the proposed effluent limitations guidelines and standards for the Metal Products and Machinery Industry (MP and M) Phase I Industry. The report assesses the cost-effectiveness of five regulatory options for indir...

1995-01-01

287

Beneficial Effect of a Short-Acting NO Donor for the Prevention of Neointimal Hyperplasia  

UK PubMed Central (United Kingdom)

Nitric oxide (NO)-based therapies effectively inhibit neointimal hyperplasia in animal models of arterial injury and bypass grafting, but are not available clinically. We created a simple, effective,...Full Text Available

2008-01-01

288

Assessing the effectiveness and cost effectiveness of adaptive e-Learning to improve dietary behaviour: protocol for a systematic review  

UK PubMed Central (United Kingdom)

BackgroundThe composition of habitual diets is associated with adverse or protective effects on aspects of health. Consequently, UK public health policy strongly advocates dietary...Full Text Available

289

Adding effect sizes to a systematic review on interventions for promoting physical activity among European teenagers  

UK PubMed Central (United Kingdom)

This commentary adds effect sizes to the recently published systematic review by De Meester and colleagues and provides a more detailed insight into the effectiveness of interventions to promote physical...Full Text Available

290

New concepts in risk assessment for patients with radiological treatment  

International Nuclear Information System (INIS)

In radiation risk assessment it must be differentiated between somatic and genetic effect on the one hand as well as between stochastic and non-stochastic effect on the other. According to definitions of the ICRP report 26 the limit for the dose equivalent of all tissues prevents non-stochastic radiation effects. With stochastic radiation effects probably exist no threshold doses; therefore the ALARA principle must be applied concerning radiation protection. The individual risk by stochastic radiation effects in its linear, linear-quadratic and quadratic extrapolations, respectively, is discussed in detail. The effective stochastic dose equivalent (H/sub eff/) as well as collective dose and collective damage are outlined.

1986-01-01

291

CT colonography and cost-effectiveness  

Energy Technology Data Exchange (ETDEWEB)

CT colonography (CTC) is increasingly advocated as an effective initial screening tool for colorectal cancer. Nowadays, policy-makers are increasingly interested in cost-effectiveness issues. A number of studies assessing the cost-effectiveness of CTC have been published to date. The majority of findings indicate that CTC is probably not cost-effective when colonoscopy is available, but this conclusion is sensitive to a number of key parameters. This review discusses the findings of these studies, and considers those factors which most influence final conclusions, notably intervention costs, compliance rates, effectiveness of colonoscopy, and the assumed prevalence and natural history of diminutive advanced polyps. (orig.)

2008-11-15

292

Science at the Theater: Hot Technology, Cool Science  

ScienceCinema

...and welcome to ...lab also known as berkeley lab my name is jeff miller and ...and a public affairs i'd like to ? ...but space is science center and ...berkeley albany high school science department and berkeley high school science department and oakland high school science ...be a q. and ...here please use and because we wanna make sure that your questions are here ...heard of also for the latest developments on science and technology ...guy we're going to be any more and more new features i hope ...and change ...thank you ? much and thank you for coming on the welcome to my world of and mayotte science journalist and what i've done for the last almost thirty years ...people about things about which there passionate and national religion tonight and ...people to explain the science and and i asking the question so what ...and ...worldwide and what it does best ? uh ...bench science and turn it into reality what do you scientists and ...uh they take scientific theory and they turn ...

293

VIGILANCE, PREDATION RISK, AND THE ALLEE EFFECT IN DESERT BIGHORN SHEEP  

Science.gov (United States)

... 2004)068[0519:VPRATA]2.0.CO;2 VIGILANCE, PREDATION RISK, AND THE ALLEE EFFECT IN DESERT ... revealed that predation risk (as es...

294

Toxicological properties of lead.  

UK PubMed Central (United Kingdom)

The pathological effects of lead on the renal, nervous, reproductive, endocrine, and immune systems have been reviewed. Emphasis is placed on reported subclinical effects due to chronic, low-level lead...Full Text Available

1977-08-01

295

Technology Improvement Pathways to Cost-Effective Vehicle Electrification: Preprint  

Energy Technology Data Exchange (ETDEWEB)

This paper evaluates several approaches aimed at making plug-in electric vehicles (EV) and plug-in hybrid electric vehicles (PHEVs) cost-effective.

2010-02-01

296

THE BALDWIN EFFECT AND GENETIC ASSIMILATION: REVISITING TWO MECHANISMS OF EVOLUTIONARY CHANGE MEDIATED BY PHENOTYPIC ...  

Science.gov (United States)

... 1111/j.1558-5646.2007.00203.x THE BALDWIN EFFECT AND GENETIC ASSIMILATION: REVISITING TWO MECHANISMS OF ... to phenotypic plast...

297

Strong-interaction effect measurements in sigma hyperonic atoms of W and Pb  

Energy Technology Data Exchange (ETDEWEB)

Strong-interaction effects have been observed in the x-ray spectra of atoms formed with [Sigma][sup [minus

1993-03-01

298

Size Effects in Impact Damage of Composite Sandwich Panels Alan ...  

Science.gov (United States)

Wade. Jackson. - Army. VTD at NASA. Langley. ABSTRACT. Panel size has a large effect on the impact response and resultant damage level of honeycomb sandwich ...

299

Saturation effects at LHC energies  

CERN Document Server

Within the framework of a modified Balitsky-Kovchegov equation, we calculated and provide estimates of non-linear saturation effects expected in the LHC range of energies.

2005-01-01

300

Possible health effects of working with VDUs.  

UK PubMed Central (United Kingdom)

A summary of the effects presented here is given in the table. The designation "factor present" implies that there is knowledge (from human or animal studies, or both) of a specific factor(s) present...Full Text Available

1989-04-01

301

Mechanism of viscosity effect on magnetic island rotation  

Energy Technology Data Exchange (ETDEWEB)

It is shown that plasma viscosity does not influence the magnetic island rotation directly. Nevertheless, it leads to nonstationarity of the plasma velocity. This nonstationarity is the reason of the viscosity effect on island rotation. (author)

2000-04-01

302

Influence of nebivolol on anticonvulsant effect of lamotrigine  

UK PubMed Central (United Kingdom)

Objective:The present study describes the effect of nebivolol (NBV) either alone or in combination with lamotrigine (LTG) using increasing current electroshock seizures...Full Text Available

2009-02-01

303

Human factors  

Energy Technology Data Exchange (ETDEWEB)

This is a presentation on Human Factors in reactor operations. It discusses issues that deal with power plant operations, training and design, operational effectiveness and safety, supporting people to achieve effective and error free performance.

2002-07-01

304

Flame Retardant Effects in PVC-Epoxidised Natural Rubber ...  

Science.gov (United States)

... Title : Flame Retardant Effects in PVC-Epoxidised Natural Rubber Miscible Blends: Halogen and Non-Halogen Based Additives,. Corporate Author : ...

1989-03-01

305

Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and ...  

Science.gov (United States)

... Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and Genomic InstabilityMary Helen Barcellos-Hoff1a ... ...

306

Efficacy and adverse effects of intravenous lignocaine therapy in fibromyalgia syndrome  

UK PubMed Central (United Kingdom)

BackgroundTo investigate the effects of intravenous lignocaine infusions (IV lignocaine) in fibromyalgia.MethodsProspective study...Full Text Available

307

Effects of phenoxybenzamine on bladder neck opening1  

UK PubMed Central (United Kingdom)

A study of the effects of the action of phenoxybenzamine on bladder neck opening during micturition is reported. Twenty patients with symptoms of prostatism but minimal prostatic enlargement were studied....Full Text Available

1980-05-01

308

Effects of Yttrium Microalloying on the Epitaxial Grain Growth ...  

Science.gov (United States)

... Accession Number : ADA137272. Title : Effects of Yttrium Microalloying on the Epitaxial Grain Growth in Ti-6Al-4V Weld Fusion Zones. ...

1983-10-01

309

Effect of ginger on gastric motility and symptoms of functional dyspepsia  

UK PubMed Central (United Kingdom)

AIM: To evaluate the effects of ginger on gastric motility and emptying, abdominal symptoms, and hormones that influence motility in dyspepsia.METHODS: Eleven patients with functional dyspepsia...Full Text Available

2011-01-07

311

Effect of Roller Profile on Cylindrical Roller Bearing ... - GLTRS - NASA  

Science.gov (United States)

J.V. Poplawski and Associates, Bethlehem, Pennsylvania. Effect of Roller Profile on Cylindrical. Roller Bearing Life Prediction. NASA/TM2000-210368 ...

312

Effect of Registration on Cyclical Kinematic Data  

UK PubMed Central (United Kingdom)

Given growing interest in Functional Data Analysis (FDA) as a useful method for analyzing human movement data, it is critical to understand the effects of standard FDA procedures, including...Full Text Available

2010-08-26

313

Effect of Deforestation on a Southwest Ghana Dung Beetle Assemblage (Coleoptera: Scarabaeidae) at the Periphery of ...  

Science.gov (United States)

... 1081:EODOAS]2.0.CO;2 Effect of Deforestation on a Southwest Ghana Dung Beetle Assemblage (Coleoptera: ... The survey provided a...

314

Diagnostics of Radionuclides Effects Results  

International Science & Technology Center (ISTC)

Development of New Methods and Means of Assessing of Consequences of Radionuclide and Heavy Metal Salt Effect, Criteria of Forecasting Physiological State and Productivity of the Farm Animals under Conditions of Ecological Pollution of Environment

315

Cooperative Effects on Transient Spectral Hole Burning  

Science.gov (United States)

... of Dist SpeA tI/ __LLL5' Page 5. 3 the coherent effects on the spontaneous radiation, we calculate the pump- field-induced ...

1992-06-01

316

Cooperative Charging Effects of Fibers From Electrospinning ...  

Science.gov (United States)

... In the Proceedings of INTC 2003, we studied charging effects on target coverage during electrospinning (16). ... of Fibers from Electrospinning of ...

2005-01-05

317

Contamination Effects of Satellite Material Outgassing ...  

Science.gov (United States)

... A detailed analysis of QCM errors is ... Surface Effects of Satellite Outgassing Products." AIAA Journal ... 9. Rauschenbach, H. S. Solar Cell Array Design ...

1990-12-01

318

Camouflage Patterns-Effects of Size and Color.  

Science.gov (United States)

... CAMOUFLAGE PATTERS- EFFECTS OFSIZE AND COL0R.-(U I'. * ... Camouflage, survei.Ilance, countersurveiliance, vi~sion, color ...

1979-07-01

319

Biological radiation effects  

International Nuclear Information System (INIS)

The stages of processes leading to radiation damage are studied, as well as, the direct and indirect mechanics of its production. The radiation effects on nucleic acid and protein macro moleculas are treated. The physical and chemical factors that modify radiosensibility are analysed, in particular the oxygen effects, the sensibilization by analogues of nitrogen bases, post-effects, chemical protection and inherent cell factors. Consideration is given to restoration processes by excision of injured fragments, the bloching of the excision restoration processes, the restoration of lesions caused by ionizing radiations and to the restoration by genetic recombination. Referring to somatic effects of radiation, the early ones and the acute syndrome of radiation are discussed. The difference of radiosensibility observed in mammalian cells and main observable alterations in tissues and organs are commented. ...

1976-01-01

320

Atmospheric Scintillation Effects on Electromagnetic Weapons  

Science.gov (United States)

... 4. TITLE AND SUBTITLE Atmospheric Scintillation Effects on Electromagnetic Weapons 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. ...

2008-12-01

321

An Intrinsic Baldwin Effect in the H Beta Broad Emission Line in the Spectrum of NGC 5548  

Science.gov (United States)

We investigate the possibility of an intrinsic Baldwin effect (i.e., nonlinear emission-line

2003-01-01

322

A framework for evolutionary systems biology  

UK PubMed Central (United Kingdom)

BackgroundMany difficult problems in evolutionary genomics are related to mutations that have weak effects on fitness, as the consequences of mutations with large effects are often...Full Text Available

329

The intrinsic nature of the Baldwin effect  

Science.gov (United States)

The relationship between the fluxes of the two strongest UV emission lines and flux in the continuum

1992-01-01

342

THE EFFECTS OF ONE MEGACYCLE ULTRASONIC ...  

Science.gov (United States)

... ULTRASONIC VIBRATION TO PORTLAND CEMENT-WATER PASTE REDUCES THE ULTIMATE COMPRESSIVE STRENGTH OF MORTARS ...

1959-09-09

343

THE EFFECT OF FIBRE MISALIGNMENT ON THE ...  

Science.gov (United States)

... and testing of unidirectional composites, there are serious doubts about the possibility of obtaining a true ultimate compressive strength for this kind ...

344

Symposium (International) (4th) on DETONATION Held at ...  

Science.gov (United States)

... 442 RHF Stresau CONFINEMENT EFFECTS IN EXPLODING BRIDGEWIRE INITIATION OF DETONATION ..... ...

1965-10-15

346

Statistical cut-off criterion  

International Nuclear Information System (INIS)

... radiation effects human populations low dose irradiation neoplasms radiation

1980-01-01

347

Some comments on BEIR III  

International Nuclear Information System (INIS)

... organizations irradiation radiation doses radiation effects RADIATIONS.

1982-01-01

351

Radioprotective effect of fish products  

International Nuclear Information System (INIS)

New fish cans were prepared in the Institute of Fish Industry, Burgas (BG), containing pectin and additives. A biological experimental study was conducted to investigate the decontaminating effect of the new products. The results demonstrated no decontaminating effect in relation to radiocesium and radiostrontium. A pronounced prophylactic effect was observed in case of external irradiation, judged by endogenous spleen colonies. (author).

1993-12-02

352

Radiological equipment for emergencies  

Energy Technology Data Exchange (ETDEWEB)

A brief guide to training and equipment needed to effectively manage victims of radiation accidents. (DT)

1985-01-01

354

Radiation technology of wood-plastic composite materials  

International Nuclear Information System (INIS)

... radiation effects RADIATIONS. WOOD-PLASTIC COMPOSITES.

1981-10-02

355

Radiation effects on the shoot tip culture of chrysanthemum  

International Nuclear Information System (INIS)

Japanese (Mar 1974). Japan Mabuchi, Toshio Kuwada, Hikaru . Kagawa Univ.,

365

PRODUCT NAME BARITE  

Wastenet

the low levels of crystalline silica in this product, chronic health effects are not anticipated with normal

366

POTENTIATION BY PENTOBARBITAL OF THE PROTECTIVE ...  

Science.gov (United States)

... Accession Number : AD0268549. Title : POTENTIATION BY PENTOBARBITAL OF THE PROTECTIVE EFFECT OF AET AGAINST GAMMA RAYS. ...

1961-10-01

369

New physics effects on Higgs production at #gamma##gamma# colliders  

International Nuclear Information System (INIS)

We study heavy physics effects on the Higgs production in #gamma##gamma# fusion using the effective Lagrangian approach. We find that the effects coming from new physics may enhance the standard model predictions for the number of events expected in the final states b-barb, WW, and ZZ up to one order of magnitude, whereas the corresponding number of events for the final state t-bart may be enhanced up to two orders of magnitude.

1996-02-20

376

Implantation-plasma treatment of martensitic steel and titanium alloy  

Energy Technology Data Exchange (ETDEWEB)

One of the effective methods of deep modification of the surface of steels and alloys is the combination of ion implantation and plasma nitriding. In this work, the long-range effect is demonstrated in the case of combination of the effect of high- and low-energy ions of nitrogen on a martensitic steel for each ion implantation is usually not effective, and a titanium alloy used widely in industry.

2001-07-01

380

Ferromagnetism in Mn-doped GaAs layers: Effects of laser annealing  

Energy Technology Data Exchange (ETDEWEB)

The properties of Mn-doped GaAs layers grown by laser deposition were investigated with measurements of Hall effect and magneto-optical Kerr effect (MOKE). The electrical and magnetic parameters of the layers were defined by growth temperature and quantity of sputtered Mn. It was shown that room-temperature ferromagnetism is revealed by MOKE and, after ruby laser 25 ns pulse annealing, by Hall effect measurements.

2006-05-15

382

Environmental Effects on Oil Pipelines  

International Science & Technology Center (ISTC)

Determination of the Ecology Factor for the Magistral Oil Pipelines, Working in Difficult Hilly and Geology Conditions

419

Effective dose equivalent in nuclear medicine investigations  

International Nuclear Information System (INIS)

... radiation hazards hazards health hazards MEDICINE. SOMATICALLY

1984-05-07

437

Effect of KI on improving copper corrosion inhibition efficiency of benzotriazole in sulfuric acid electrolytes  

Energy Technology Data Exchange (ETDEWEB)

A synergistic effect exists when benzotriazole (BTAH) and iodide ions are used together to prevent the corrosion of copper in sulfuric acid. The nature of this effect has been studied systematically by using electrochemical techniques and X-ray photoelectron spectroscopy. The synergistic effect is due largely to the formation of a film of Cu(IBTA) complex and is probably polymeric in nature. This new complex film greatly depresses copper dissolution.

1993-10-01

439

Effect of High Omega-3 Fish Intake on Lipid Peroxidation  

Science.gov (United States)

Omega-3 Fatty Acids; Lipid Peroxidation

2011-05-31

461

EFFECT OF SHIP ATTITUDE AND SHIP MOTION ON PRIMARY COOLANT SYSTEM FLOW RATES. Appendix A: DERIVATION OF EFFECT OF ANGULAR ACCELERATION ON DRIVING HEAD IN A NATURAL CIRCULATION REACTOR  

Science.gov (United States)

Analytical techniques for analyzing the effects of ship motion and attitude on the primary coolant system flow rates are presented. Design data for minimizing these effects are given. (C.J.G.)

1960-01-24

462

EFFECT OF MICROSTRUCTURE ON THE STRENGTH ...  

Science.gov (United States)

... THE STRENGTH, TOUGHNESS, AND STRESS-CORROSION CRACKING SUSCEPTIBILITY OF A METASTABLE BETA TITANIUM ALLOY (Ti-11. ...

1970-02-01

463

Conversion gain in a Josephson effect mixer  

International Nuclear Information System (INIS)

United States Taur, Y. Claassen, JH Richards, PL Department of Physics,

464

Contribution to the radiation preparation of wood-plastic materials. Pt. 7  

International Nuclear Information System (INIS)

... odd nuclei organic compounds radiation effects radioisotopes synthesis

1974-01-01

465

Contribution to the radiation preparation of wood-plastic materials. Pt. 6  

International Nuclear Information System (INIS)

... compounds polymers polyolefins polyvinyls radiation effects SYNTHESIS.

1974-01-01

466

Contribution to the radiation preparation of wood-plastic materials Pt. 3  

International Nuclear Information System (INIS)

... compounds plants radiation effects radioisotopes reaction kinetics trees

1974-01-01

467

Continuous Strategy Development for Effects-Based ...  

Science.gov (United States)

... BAE Systems Advanced Information Technologies, Inc. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. ...

2006-02-01

468

Climate Change: The Role of Particles and Gases  

ScienceCinema

...global warming ...the effects of global warming ...also the ? that global warming ...

470

Calculation of some energetic parameters of astatine compounds  

International Nuclear Information System (INIS)

... astatine complexes astatine compounds coulomb energy effective charge

471

CRC handbook of biological effects of electromagnetic fields  

Energy Technology Data Exchange (ETDEWEB)

This book presents the current knowledge about the effects of electromagnetic fields on living matter. The three-part format covers dielectric permittivity and electrical conductivity of biological materials; effects of direct current and low frequency fields; and effects of radio frequency (including microwave) fields. The parts are designed to be consulted independently or in sequence, depending upon the needs of the reader. Useful appendixes on measurement units and safety standards are also included.

1986-01-01

472

Biophotonics and Bone Biology  

Science.gov (United States)

One of the more-serious side effects of extended space flight is an accelerated bone loss

2004-01-01

488

ADULT ACQUIRED TOLERANCE TO HOMOGRAFTS.  

Science.gov (United States)

... The effectiveness of immune suppression with both 6-mercaptopurine and methotrexate was insufficient to permit induction of a clinically useful ...

1967-07-31

489

A study of the Baldwin effect in the IUE data set  

Science.gov (United States)

The paper investigates the controversial relation between the continuum luminosity and the C IV 1550 emission-line strength in the spectra of quasars, commonly referred to as the Baldwin effect, as a possible indicator of absolute luminosity. It is concluded that the Baldwin effect does represent a physical correlation between the continuum and the C IV 1550 equivalent width rather than a consequence of selection effects. In addition to the C IV results, a similar relation is found for the Lyman-alpha emission line. 38 refs.

1990-07-01

495

The importance of axial effects for borehole design of geothermal heat-pump systems  

Energy Technology Data Exchange (ETDEWEB)

This paper studies the effects of axial heat conduction in boreholes used in geothermal heat pump systems. The axial effects are examined by comparing the results obtained using the finite and infinite line source methods. Using various practical design problems, it is shown that axial effects are relatively important. Unsurprisingly, short boreholes and unbalanced yearly ground loads lead to stronger axial effects. In one example considered, it is shown that the borehole length is 15% shorter when axial conduction effects are considered. In another example dealing with underground water freezing, the amount of energy that has to be removed to freeze the ground is three times higher when axial effects are considered. (author)

2010-04-15

496

Numerical analysis of methane-air combustion considering radiation effect  

Energy Technology Data Exchange (ETDEWEB)

Turbulent premixed methane-air combustion in a cylindrical chamber is numerically simulated considering radiation effect. Reaction rates are considered as minimum rates between Arrhenius rates and eddy break up rates. A five step reduced mechanism is used. Turbulent modeling is done via standard k-{epsilon} model imposed by empirical inlet boundary conditions. Source terms of energy equation consist of reaction rates and radiation effects. The discrete ordinate method (DOM) is employed to solve the radiative transfer equation (RTE) and the weighted sum of gray gas model (WSGGM) is imposed to consider radiation effect of non-gray gases. The results indicate that in the case of turbulent combusting flows, the effect of radiation of gases can affect the temperature and species concentrations. The numerical results obtained considering radiation effect are closer to the experimental ...

2008-12-15

497

Numerical analysis of methane-air combustion considering radiation effect  

International Nuclear Information System (INIS)

Turbulent premixed methane-air combustion in a cylindrical chamber is numerically simulated considering radiation effect. Reaction rates are considered as minimum rates between Arrhenius rates and eddy break up rates. A five step reduced mechanism is used. Turbulent modeling is done via standard k-? model imposed by empirical inlet boundary conditions. Source terms of energy equation consist of reaction rates and radiation effects. The discrete ordinate method (DOM) is employed to solve the radiative transfer equation (RTE) and the weighted sum of gray gas model (WSGGM) is imposed to consider radiation effect of non-gray gases. The results indicate that in the case of turbulent combusting flows, the effect of radiation of gases can affect the temperature and species concentrations. The numerical results obtained considering radiation effect are closer to the experimental data than ...

2008-12-01

498

Biological effects of electromagnetic radiation in the microwave range  

Energy Technology Data Exchange (ETDEWEB)

The book examines current experimental and clinical knowledge concerning the biological and biophysical effects of electromagnetic radiation, particularly that in the microwave range. The biophysical bases of the interaction of electromagnetic radiation with matter are reviewed with emphasis on biological systems, and the effects of radiation on critical biological systems, including the nervous, reproductive, visual and blood-forming systems are compared. Data concerning the lethal effects of nonionizing radiation is presented and characteristics of the effects of electromagnetic radiation on the whole mammalian organisms are examined. Various reactions of the neuroendocrine system to electromagnetic radiation are described, with particular attention given to the adrenal system, and the combined effects of ionizing and microwave radiation in the flight environment are discussed. ...

1980-01-01

499

Afferent mechanisms of microwave-induced biological effects. Annual report, 1 June 1985-31 May 1986  

Energy Technology Data Exchange (ETDEWEB)

Effects of 2450-MHz circularly polarized microwave irradiation on central nervous system functions were studied. Pulsed (microsecond, 500 pps) microwaves decreased high-affinity sodium-dependent choline uptake in the hippocampus and frontal cortex of the rat. The effect on hippocampal choline uptake was blocked by pretreatment with narcotic antagonists. Continuous-wave microwaves of the same power density decreased choline uptake in the frontal cortex only. Furthermore, it was found that the effects of pulsed microwaves on central cholinergic activity are classically conditionable to cues in the exposure environment. The hypothesis that some of the neurological effects of pulsed microwave irradiation are caused by its effect on the auditory system was investigated. Effects of pink noise and pulsed microwaves were compared.

1986-07-01