o-naphthoquinone cg 10-248: Topics by WorldWideScience.org

Extraction and purification of free oligosaccharides in Maytenus ilicifolia

English 2006 [1 p.] Brazil Uratani, JM Cipriani, TR Mellinger, CG Gorin,

2006-07-01

Demonstration/Validation of the TC-25 Donovan Blast ...

English 2005 [1 p.] Brazil Uratani, JM Cipriani, TR Mellinger, CG Gorin,

2005-07-02

Arabinogalactans isolated from the medicinal plant Maytenus ilicifolia

... During operations, the system successfully treated Phosgene (CG), chloropicrin (PS), a smoke-generating formulation based on hexachloroethane ...

2004-05-01

A type II arabinogalactan isolated from an infusion of Maytenus ilicifolia

English 2006 [1 p.] Brazil Cipriani, TR Mellinger, CG Gorin, PAJ Sassaki,

2006-07-01

A Lamarckian Hybrid of Differential Evolution and Conjugate Gradients for Neural Network Training

English 2005 [1 p.] Brazil Cipriani, TR Mellinger, CG Sassaki, GL Gorin,

2005-07-02

British Library Electronic Table of Contents (United Kingdom)

The paper describes two schemes that follow the model of Lamarckian evolution and combine differential evolution (DE), which is a population-based stochastic global search method, with the local optimization algorithm of conjugate gradients (CG). In the first, each offspring is fine-tuned by CG before competing with their parents. In the other CG is used to improve both parents and offspring in a manner that is completely seamless for individuals that survive more than one generation. Experiments involved training weights of feed-forward neural networks to solve three synthetic and four real-life problems. In six out of seven cases the DE?CG hybrid, which preserves and uses information on each solution?s local optimization process, outperformed two recent variants of DE.

2010-01-01

Catestatin (chromogranin A_344-364) is a novel cardiosuppressive agent: inhibition of isoproterenol and endothelin signaling in the frog heart

The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN study*

The catecholamine release-inhibitory catestatin [Cts; human chromogranin (Cg) A_352-372, bovine CgA_344-364] is a vasoreactive and anti-hypertensive peptide derived...Full Text Available

2008-07-01

Non-contiguous regions of Z-DNA in a DNA dodecamer.

Chronically elevated interleukin-6 (IL-6) affects lipid and lipoprotein metabolism. Individuals genetically predisposed to higher IL-6 secretion may be at risk of dyslipidemia, especially during the...Full Text Available

2008-08-01

A cytosine methyltransferase homologue is essential for repeat-induced point mutation in Neurospora crassa

The conformation of the self-complimentary DNA dodecamer d(br5CGbr5CGAATTbr5CGbr5CG) has been investigated in a variety of salt and solvent conditions by one and two-dimensional 1H NMR. In low salt...Full Text Available

1989-10-11

Development of an assay for a biomarker of pregnancy and early fetal loss

During sexual development, Neurospora crassa inactivates genes in duplicated DNA segments by a hypermutation process, repeat-induced point mutation (RIP). RIP introduces C:G to T:A...Full Text Available

2002-06-25

Suitability of permitted explosives and sheathed explosives for blasting in mines

Human chorionic gonadotropin (hCG) is a glycoprotein hormone, secreted by the syncytiotrophoblast cells of the fertilized ovum, that enters the maternal circulation at the time of endometrial implantation. It is composed of two nonidentical subunits; ..cap alpha.. and ..beta.., with molecular weights of 14 kD and 23 kD, respectively. Human chorionic gonadotropin binds to the same receptor as hLH and displays the same biological response, namely, to stimulate the declining function of the corpus luteum to produce progestins and estrogen late in the menstrual cycle. The differences in the structures of hCG and hLH have been exploited to develop antibodies that can measure hCG specifically in the presence of hLH. Two-site antibody binding assays have been developed, based on a surface immunological concept of hCG epitopes, that involve four distinct regions to which antibodies against ...

1987-10-01

Transplantation of engineered bone tissue using a rotary three-dimensional culture system.

This paper discusses use of chemical explosives for blasting in underground coal mines endangered by methane, and reviews safety regulations on blasting in mines endangered by methane in Poland. Results of tests carried out by the Institute for Mine Safety of the Central Mining Institute in Katowice are reviewed. The following types of explosives were tested: the L permitted Barbaryt, the FGH2 permitted Barbaryt, the D6G permitted Metanit, the D5G permitted Metanit, the W2AG permitted Metanit, the CG sheathed permitted Metanit. Test results are given in a table and 2 diagrams. Comparative evaluations show that the CG sheathed permitted Metanit and the W2AG permitted metanit are superior to other explosives. Methods for evaluating safety of explosives for blasting in coal mines endangered by methane are reviewed. Indices characterizing safety of chemical explosives are evaluated. (3 refs.) (In Polish)

1983-11-01

Technique of moving picture overlapping for view simulation by means of the moving picture processing; Dogazo kaiseki ni motozuku keikan simulation no tame no dogazo goseiho

Bone is a complex, highly structured, mechanically active, three-dimensional (3-D) tissue composed of cellular and matrix elements. We previously published a report on in situ collagen gelation using a rotary 3-D culture system (CG-RC system) for the construction of large tissue specimens. The objective of the current study was to evaluate the feasibility of bone tissue engineering using our CG-RC system. Osteoblasts from the calvaria of newborn Wistar rats were cultured in the CG-RC system for up to 3 wk. The engineered 3-D tissues were implanted into the backs of nude mice and calvarial round bone defects in Wistar rats. Cell metabolic activity, mineralization, and bone-related proteins were measured in vitro in the engineered 3-D tissues. Also, the in vivo histological features of the transplanted, engineered 3-D tissues were evaluated in the animal models. We found that metabolic activity increased in the engineered 3-D ...

2007-03-11

Systematic implicit solvent coarse-graining of bilayer membranes: lipid and phase transferability of the force field

This paper proposes a technique of moving picture overlapping for view simulation by means of the moving picture processing. The continuous pictures of actual natural view gotten from video and the pictures of building structure made by computer graphics (CG) were overlapped. The CG pictures of building structure model were made considering the camera parameters, such as position and direction of camera. In order to analyze the continuously changing camera parameters, optical flows were determined from the view video. Based on these results, the overlapping video was made, in which the building structure was incorporated into the actual view. Furthermore, the proposed technique of moving picture overlapping was applied to the view simulation of transmission line tower. Consequently, it was demonstrated that the overlapped moving pictures can provide information which can not be obtained from the still pictures. It was experimentally confirmed ...

1994-11-01

Localization of highly repetitive, species-specific EcoRI elements from 'Lupinus luteus' L

We study the lipid and phase transferability of our recently developed systematically coarse-grained solvent-free membrane model. The force field was explicitly parameterized to describe a fluid 1-palmitoyl-2-oleoyl-phosphatidylcholine (POPC) bilayer at 310 K with correct structure and area per lipid, while gaining at least three orders of magnitude in computational efficiency (see Wang and Deserno 2010 J. Phys. Chem. B 114 11207-20). Here, we show that exchanging CG tails, without any subsequent re-parameterization, creates reliable models of 1,2-dioleoylphosphatidylcholine (DOPC) and 1,2-dipalmitoylphosphatidylcholine (DPPC) lipids in terms of structure and area per lipid. Furthermore, all CG lipids undergo a liquid-gel transition upon cooling, with characteristics like those observed in experiments and all-atom simulations during phase transformation. These studies suggest a promising transferability of our force field parameters to ...

2010-09-01

Association and expression study of synapsin III and schizophrenia

Using Southern, dot-blot and 'in situ' hybridization, molecular and cytological localization of repetitive 'Lupinus lueteus' DNA sequence was shown. Under CsCl gradient centrifugation conditions CG-rich satellite fraction appeared. Dot-blot hybridization clearly indicated that 1070bp repetitive element being a member of previously described EcoRI fragments family appeared only in the main band. The use of that DNA fragment as an 'in situ' hybridization signal in the euchromatin area. (author). 26 refs, 3 figs.

British Library Electronic Table of Contents (United Kingdom)

The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter release and in synaptogenesis, suggesting a potential role in several neuropsychiatric diseases. The human SYN3 gene is located on chromosome 22q12-13, a candidate region implicated in previous linkage studies of schizophrenia. However, association studies of SYN3 and schizophrenia have produced inconsistent results. In this study, four SYN3 SNPs (rs133945 (-631 C>G), rs133946 (-196 G>A), rs9862 and rs1056484) were tested in three sets of totally 3759 samples that comprise 655 affected subjects and 626 controls in the Irish Case-Control Study of Schizophrenia (ICCSS), 1350 samples incorporating 273 pedigrees in the Irish Study of High D...

2009-01-01

Cold pressor test myocardial perfusion SPECT as a predictor of the development of ischemia at exercise in the follow up of asymptomatic patients with moderate cardiovascular risk

Hydatidiform mole and fetus with normal karyotype: support of a separate entity.

Introduction: Previous studies have published the correlation between myocardial perfusion SPECT (MP) during cold pressor test (CPT) and intracoronary acetylcholine and its usefulness as independent marker of endothelial dysfunction (ED). Objective: To analyze the incidence of positivization of MP exercise studies in the follow up of asymptomatic patients with moderate cardiovascular risk (CV) and ED detected by PF. Material and Methods: Of 301 patients of the PARADIGMA Registry (normal exercise MP SPECT and clinical probability < 20% of events at 10 years [moderate risk by Framingham index]) 55 had positive PF (+) (18.3%). Prospectively and consecutively, 15 asymptomatic patients with PF (+), and a control group (CG) of 15 patients with negative PF, with paired sex, age and coronary risk factors (CRF), that accomplished a 12 #+-# 2 months follow up, and that underwent a new exercise and resting MP SPECT were analyzed. An MP extension score was used in a model ...

DEFF Research Database (Denmark)

Repetitive hydatidiform mole was observed in four pregnancies. The pregnancies presented with heavy bleeding and vomiting, but the post-evacuation courses were uncomplicated, with rapid regression of serum hCG levels. Cytogenetic investigations, analyses of restriction fragment length polymorphisms, and flow cytometry in three pregnancies were consistent with diploid, biparental conception as the origin of fetal tissue and molar and nonmolar villi. In one pregnancy, the analyses of cytogenetic markers suggested the coexistence of two different cell lines of dizygotic, biparental origin, whereas DNA analysis was consistent with a single conception. With incomplete genetic information, a hydatidiform mole with coexistent normal fetus is generally considered to result from dizygous twinning comprising an androgenetic complete mole and a normal conception. In the present gestations, the results based on several techniques applied on numerous samples from different ...

1991-01-01

1 2

Competition by inhibitory oligonucleotides prevents binding of CpG to C-terminal TLR9

British Library Electronic Table of Contents (United Kingdom)

Abstract TLR9 recognizes unmethylated CpG-containing DNA commonly found in bacteria. Synthetic oligonucleotides containing CpG-motifs (CpG ODNs) recapitulate the activation of TLR9 by microbial DNA, whereas inversion of the CG dinucleotide within the CpG motif to GC (GpC ODNs) renders such ODNs inactive. This difference cannot be attributed to binding of ODNs to the full-length TLR9 ectodomain, as both CpG and GpC ODNs bind comparably. Activation of murine TLR9 requires cleavage into an active C-terminal fragment, which binds CpG robustly. We therefore compared the ability of CpG and GpC ODNs to bind to full-length and C-terminal TLR9, and their impact on the cleavage of TLR9. We found that CpG binds better to C-terminal TLR9 when compared with GpC, despite comparably low binding of both O...

2011-01-01

Potential of sub-ablative pulsed CO{sub 2} laser irradiation on inhibition of artificial caries-like lesion progress in bovine dental enamel; Potencial de inibicao da progressao da carie artificial por irradiacao sub-ablativa com laser de CO{sub 2} pulsado em esmalte dental bovino

Primary structures of four trypsin inhibitor E homologs from venom of Dendroaspis angusticeps: structure-function comparisons with other dendrotoxin homologs.

The aim of this study was to investigate whether sub-ablative pulsed C0{sub 2} laser (1 0,6 {mu}m) irradiation is capable of reducing the susceptibility of the dental enamel to demineralization, and thus achieving a potential caries-protective effect. The crowns of 51 bovine front teeth, embedded in acrylic resin and polished until exposure of flat enamel surface, were used. The samples were cut in cubes of 10x10 mm, and totally coated with acid-resistant nail varnish, except for an enamel exposed window of 16 mm square. Three groups (n=17) were obtained: control group (CG) not irradiated; group laser A (LA) and group laser B (LB) where the samples were irradiated. The conditions were 60 mJ, 100 Hz, 0,3 J/cm{sup 2} for LA and 135 mJ, 10 Hz, 0,7 J/cm{sup 2} for LB. Two samples of each group were submitted to SEM analysis and fifteen to demineralization in 3 ml acetate buffer solution (0,1 mol/L) with pH 4,5 for 24h at 37 deg C, with regular agitation. After the ...

2005-07-01

Origin of {gamma}-rays from young open clusters

Four trypsin inhibitor homologs, the first known from Dendroaspis angusticeps venom, were characterized using a combination of gel filtration, cation exchange, reverse-phase liquid chromatography, Edman degradation and mass spectrometry. The four toxins comprise two 57 residue and two 59 residue isoforms. The long toxins possess a Lys-Gln N-terminal extension lacked by the short toxins. The only other structural difference is an Arg/His replacement at position 55. The long Arg55 variant is identical to trypsin inhibitor E from the venom of Dendroaspis polylepis. The name epsilon-dendrotoxin is suggested so as to follow the nomenclature of Benishin, C.G., Sorensen, R.G., Brown, W.E., Krueger, B.K., Blaustein, M.P., 1988. Four polypeptide components of green mamba venom selectively block certain potassium channels in rat brain synaptosomes. Mol. Pharmacol. 34, 152-159. Among snake venom protease inhibitors, the epsilon-dendrotoxins are structurally most like the ...

2002-03-01

Development of an efficient parallel FEM analysis program for large structural problems over several millions of DOF

The young open cluster Berkeley 87 was predicted to be associated with the COS B {gamma}-ray source 2CG 075+00 on the basis of the experimental evidence of the presence of a shock front around the Wolf - Rayet star ST3 placed in the inner part of the cluster. The CGRO phase-1 data confirm this identification. Protons accelerated at the shock boundary can produce {pi} deg. via p-p interactions and then {gamma}-rays. With the measured flux F{sub {gamma}} (E > 100 MeV) {approx_equal} 9x10{sup -7} ph cm{sup -2} s{sup -1} and the power-law proton spectrum with spectral index {gamma} = 2, the cosmic-ray-energy-density in the inner part ({approx} 0.8 pc radius) of Berk 87 is about 100 times greater than that in the vicinity of the Earth. We have calculated {gamma}-ray spectra expected from the decay of {pi}{sup d}eg. produced in p-p interactions. The spectra have been normalized to the observed flux of Berk 87 by using different input proton spectra. The comparison ...

1996-08-01

Determination of volatiles produced during radiation processing in food and medicinal herbs; Determinacao de volateis produzidos durante o processamento por radiacao em ervas alimenticias e medicinais

In order to predict or to evaluate the structural reliability of a variety of nuclear components under actual changing operating conditions, it is necessary to take the detailed geometrical features of components into consideration on one hand, and thermo-mechanical loading conditions with space and time variations during the lifetime, on the other hand. This consideration leads the authors to develop a super large-scale structural analysis program based on a parallel computational FEM with a variable scale of PC cluster architecture, whose prototype system is presented in a companion paper in this Symposium. Development of the PC cluster technology is one of the most important subjects in large-scale structural simulation, reducing computer costs and thus making simulation more acceptable to the engineering community. This paper presents the developmental status of the parallel FEM solver, demonstrating computational capabilities with three dimensional effects taking into ...

2000-09-01

Association and expression study of synapsin III and schizophrenia.

In order to protect food from pathogenic microorganisms as well as to increase its shelf life while keeping sensorial properties (e.g. odor and taste), once the latter are one of the main properties required by spice buyers, it is necessary to analyze volatile formation from irradiation of medicinal and food herbs. The aim of the present study was to analyze volatile formation from Co irradiation of Laurus Cinnamomum, Piper Nigrum, Origanum Vulgare and Myristica Fragans. Possible changes on the odor of these herbs are evaluated by characterizing different radiation doses and effects on sensorial properties in order to allow better application of irradiation technology. l he samples have been irradiated in plastic packages by making use of a {sup 60}Co Gamma irradiator. Irradiation doses of 0, 5, 10, 15, 20 and 25kGy have been tested. For the analysis of the samples, SPME has been applied, while for the analysis of volatile compounds, CG/MS. Spice irradiation has ...

2008-07-01