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NASA - 06-03-2009  

Jun 3, 2009... (Water Recovery & Management) assessment of onboard water supplies. ... all empty), 4. waste/EMU dump and other (3 CWCs with 67.5 L). ... It is located in the western part of Chad, bordering on northeastern Nigeria.

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The Role of Teachers in Sex Education and the Prevention and Control of HIV/AIDS in Nigeria  

Research was undertaken to assess the role of primary school teachers with regard to the prevention and control of HIV/AIDS in Nigeria. Structured and semi-structured questionnaires were responded to by 210 teachers drawn from primary schools in Eastern Nigeria (with pupils aged 6-15 years). These were supplemented by focus group discussions and key informant interviews. The findings show that the teachers have a reasonably high knowledge of the modes of HIV transmission, the behavioural risk factors and modes of prevention. The teachers, however, are reluctant to teach this because of socio-cultural and religious factors, lack of teacher training in delivery of sex education as well as poor motivation. The motivation and participation of primary school teachers in the prevention of HIV in Nigeria are very low. This calls for serious and urgent policy intervention to remedy the situation and increase the role of primary school teachers in combating the spread of HIV/AIDS in Nigeria. (Contains 3 tables.)

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Changes in the timing of sexual initiation among young Muslim and Christian women in Nigeria.  

Sexual initiation during adolescence has important demographic and health consequences for a population, yet no systematic analysis of changes in the timing of sexual initiation has been conducted in Nigeria. Two rounds of national surveys conducted in 1990 and 2003 were used to examine changes in the timing of sexual initiation among female adolescents in Nigeria. Multivariate survival analysis using Cox proportional hazards models was used to assess changes in the risk of sexual initiation and to identify the correlates of first sex. Contrary to what has been reported in several Nigerian studies, there was no decline in age at first sex among Christian adolescents. Age at first sex did not change significantly for Christian adolescents, although premarital sex appears to have increased-primarily due to an increase in the age at marriage. Age at first sex did increase among Muslim women. Premarital sex remained low among Muslim women. A number of socioeconomic variables were associated with the timing of sexual initiation. Weekly exposure to the mass media was associated with earlier sexual initiation. The degree to which an environment was liberal or restrictive was a key determinant of the timing of sexual initiation in Nigeria. The findings also illustrate the important role of socioeconomic factors in determining the timing of sexual initiation in Nigeria. As secondary education increases in Northern Nigeria, additional increases in the age at sexual debut are likely among Muslim women. The study raises concerns about the influence of the mass media on the timing of first sex in Nigeria. The evidence of an absence of changes in the timing of sexual initiation among Christian women in more than a decade implies that programs which aim to delay the timing of sexual initiation in Southern Nigeria may have limited success. With age at marriage already high among Christian women, programs that focus on abstinence until marriage may also be pursuing an approach with limited chances of success. PMID:18712467

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Knowledge, attitudes and practices of AIDS associated malignancies among people living with HIV in Nigeria.  

ABSTRACT: INTRODUCTION: The epidemic of HIV in sub-Saharan Africa varies significantly across countries in the region with high prevalence in Southern Africa and Nigeria. Cancer is increasingly identified as a complication of HIV infection with higher incidence and mortality in this group than in the general population. Without cancer prevention strategies, improved cancer treatment alone would be an insufficient response to this increasing burden among people living with HIV (PLHIV). Although previous studies have noted low levels of awareness of cancers in sub-Saharan Africa none has examined the knowledge and perceptions of cancer among beneficiaries of a large PEPFAR program in Nigeria. METHODS: Focus group discussions (FGD) and Key Informant Interviews (KII) were carried out in 4 high volume tertiary care institutions that offer HIV care and treatment in Nigeria. FGD and KII assessed participants' knowledge of cancer, attitudes towards cancer risk and cancer screening practices. RESULTS: The mean age of participants was 38 years. Most participants had heard about cancer and considered it a fatal disease but displayed poor knowledge of the causes and of AIDs associated cancers. PLHIV in Nigeria expressed attitudes of fear, denial and disbelief as to their perceived cancer risk. Some of the participants had heard about cancer screening but very few participants had been screened. CONCLUSION: Our findings of poor knowledge of cancer among PLHIV in Nigeria indicate the need for health care providers and the government to intervene by developing primary cancer prevention strategies for this population. PMID:23098099

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Potential Availability of Energetically Usable Crop Residues in Nigeria  

An assessment of the potential availability of selected residues from maize, cassava, millet, plantain, groundnuts, sorghum, oil palm, palm kernel, and cowpeas for possible conversion to renewable energy in Nigeria has been made. It is estimated that nearly 58 million tonnes of these residues were potentially available in the year 2004 with energy potential of about 20.8 million tonnes oil equivalents. The residue availability for 2010 is projected to be about 80 million tonnes. These residues, when converted to energetically usable forms, can substitute or complement the fossil energy sources in Nigeria by more than 80%.

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Could fuelwood use contribute to household poverty in Nigeria?  

To show whether fuelwood use could contribute to household poverty in Nigeria, the paper has used the discounted cash flow microeconomic assessment to evaluate the annual worth cost of harnessing fuel wood for cooking and water heating in Nigerian households, for an average household size of five persons per day. Findings indicate that 9786 Naira is being expended on cooking and water heating activities at the household level in Nigeria which is much greater than the mean national household income of about 5150 Naira a year. The study has shown that households using fuelwood are made poorer and left with no savings. (Author)

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Bushmeat trade in the Cross-Sanaga rivers region: Evidence for the importance of protected areas  

Exploitation of wildlife for meat in the tropics (`bushmeat') is a critical threat for biodiversity, particularly in Africa. Here, we investigate the importance of protected areas (National Parks and other forest parks) as sources for the trade by exploring patterns in pricing and condition of bushmeat carcasses. We surveyed carcass prices in a large sample of trading points (87 markets surveyed, over a 35,000km2 area) in Cameroon and Nigeria in the Cross-Sanaga region of West Africa. We assessed evidence for national parks as the source of animals traded as bushmeat. The study area included rural and urban centers (Calabar, Nigeria, and Douala, Cameroon) close to important protected areas: the Cross River National Park in Nigeria, and Korup National Park in Cameroon. Both parks host very ...

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Seroprevalence of poliovirus antibodies amongst children in Zaria, Northern Nigeria  

Background: Poliomyelitis is endemic in Northern Nigeria where there is continuous transmission of wild poliovirus 1 and 3 (WPV1 and 3) and circulating vaccine derived poliovirus 2 (cVDPV2) resulting in a high number of cases of children with acute flaccid paralysis. The seroprevalence of antibodies to polio serotypes which can be used to assess the immune status of children and the effectiveness of the vaccine against poliomyelitis is unknown, despite its endemicity in this part of the world. Objective: This study aimed to determine the seroprevalence of poliovirus antibodies in children aged 1-10 years in Zaria, Northern Nigeria. Methods: A descriptive, cross sectional, community based study was undertaken in Zaria, North Western Nigeria between 2008 and 2009. Two hundred and sixty-four ...

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Unavailability of Essential Obstetric Care Services in a Local Government Area of South-West Nigeria  

This paper reports the findings at baseline in a multi-phase project that aimed at reducing maternal mortality in a local government area (LGA) of South-West Nigeria. The objectives were to determine the availability of essential obstetric care (EOC) services in the LGA and to assess the quality of ...

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Efficacy and Safety Assessment of T. Angelica Herbal Tonic, a Phytomedicinal Product Popularly Used in Nigeria  

T. Angelica Herbal Tonic (TAHT) is a herbal product indicated for indigestion and constipation and highly patronized in Nigeria. In this study, the efficacy and safety of the herbal tonic in relation to the label claims were assessed. The effect on peristalsis in mice was evaluated by the charcoal m...

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Development of a WHO Child Care Facility Schedule (CCFS): a pilot collaborative study.  

This paper describes the research conducted by a WHO collaborative study group for the development of a questionnaire method for the assessment of quality in child-care settings. The results of an inter-rater reliability study undertaken in Greece and Nigeria suggest that the Child Care Facility Sch...

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The history and future of water management of the lake Chad basin in Nigeria L'homme et l'eau dans le bassin du lac Tchad = Man and water in the lake Chad basin  

The history of water management in Nigeria has been essentially a history of large capital projects, which have often been executed without comprehensive assessments of either the effects on downstream users or on the environment. In the case of the Chad basin, the principal river systems bringing w...

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Environmental risk management and preparations for the first deep water well in Nigeria  

Statoil is among the leaders in protecting health, environment and safety in all aspects of the business. The evaluations of business opportunities and development of blocks opened by authorities for petroleum exploration, are assessed in accordance with the goals for environmental protection. Progressive improvement of environmental performance is secured through proper environmental risk management. In 1995, Statoil, the technical operator on Block 210 off the Nigerian coast, was the first company to drill in deep waters in this area. An exploration well was drilled in a water depth of about 320 meters. The drilling preparations included environmental assessment, drillers Hazop, oil spill drift calculations, oil spill response plans and environmental risk analysis. In the environmental preparations for the well, Statoil adhered to local and national government legislation, as well as to international guidelines and company standards. Special attention was paid to the environmental sensitivity of potentially affected areas. Statoil co-operated with experienced local companies, with the authorities and other international and national oil companies. This being the first deep water well offshore Nigeria, it was a challenge to co-operate with other operators in the area. The preparations that were carried out, will set the standard for future environmental work in the area. Co-operation difficulties in the beginning were turned positively into a attitude to the environmental challenge.

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Cholera epidemiology in Nigeria: an overview.  

Cholera is an acute diarrhoeal infection caused by ingestion of food or water contaminated with the bacterium, Vibrio cholera. Choleragenic V. cholera O1 and O139 are the only causative agents of the disease. The two most distinguishing epidemiologic features of the disease are its tendency to appear in explosive outbreaks and its predisposition to causing pandemics that may progressively affect many countries and spread into continents. Despite efforts to control cholera, the disease continues to occur as a major public health problem in many developing countries. Numerous studies over more than a century have made advances in the understanding of the disease and ways of treating patients, but the mechanism of emergence of new epidemic strains, and the ecosystem supporting regular epidemics, remain challenging to epidemiologists. In Nigeria, since the first appearance of epidemic cholera in 1972, intermittent outbreaks have been occurring. The later part of 2010 was marked with severe outbreak which started from the northern part of Nigeria, spreading to the other parts and involving approximately 3,000 cases and 781 deaths. Sporadic cases have also been reported. Although epidemiologic surveillance constitutes an important component of the public health response, publicly available surveillance data from Nigeria have been relatively limited to date. Based on existing relevant scientific literature on features of cholera, this paper presents a synopsis of cholera epidemiology emphasising the situation in Nigeria. PMID:22937199

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Characterization of methicillin-susceptible and -resistant staphylococci in the clinical setting: a multicentre study in Nigeria.  

ABSTRACT: BACKGROUND: The staphylococci are implicated in a variety of human infections; however, many clinical microbiology laboratories in Nigeria do not identify staphylococci (in particular coagulase negative staphylococci - CNS) to the species level. Moreover, data from multi-centre assessment on antibiotic resistance and epidemiology of the staphylococci are not available in Nigeria. This study investigated 91 non-duplicate staphylococcal isolates obtained from the microbiology laboratories of eight hospitals in Nigeria during the period January to April 2010. METHODS: Identification and antibiotic susceptibility testing was performed using the VITEK 2 system, detection of resistance genes by PCR, and molecular characterization was determined by SCCmec typing, spa and multilocus sequence typing (MLST). RESULTS: All the isolates were susceptible to mupirocin, tigecycline, vancomycin and linezolid, but 72.5% of CNS and 82.3% of Staphylococcus aureus were resistant to cotrimoxazole, while multiresistance was observed in 37 of the 40 CNS isolates. Untypeable SCCmec types (ccrC/Class A mec and ccr-negative/Class C2 mec gene complex) in two methicillin-resistant S. aureus (MRSA) were identified. Additionally, ccr-negative/Class A mec and ccr type 4/Class C2 mec gene complex was detected in one isolate each of S. sciuri and S. haemolyticus, respectively. The S. aureus isolates were classified into 21 spa types including two new types (t8987, t9008) among the methicillin-susceptible S. aureus (MSSA) isolates. Two (CC8-SCCmecnon-typeable and CC88-SCCmec IV) and four (CC8-SCCmec III/IV/V; CC30-SCCmec II/III; CC88-SCCmec IV; and ST152-SCCmecnon-typeable) MRSA clones were identified in Maiduguri (North-East Nigeria) and South-West Nigeria, respectively. The proportion of Panton-Valentine leukocidin (PVL)-positive MSSA was high (44.4%) and 56.3% of these strains were associated with sequence type (ST) 152. CONCLUSIONS: The identification of multiresistant mecA positive S. haemolyticus and S. sciuri from clinical samples indicates that characterization of CNS is important in providing information on their diversity and importance in Nigeria. There is the need to develop new SCCmec classification methods for non-typeable methicillin-resistant staphylococci, and to curtail the spread and establishment of the S. aureus ST152 clone in Nigeria. The study presents the first report of a PVL-positive ST152-SCCmecnontypeable MRSA and SCCmec typing of methicillin-resistant CNS in Nigeria. PMID:23121720

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Sexual behaviour and contraceptive use among secondary school students in Ilesha south west Nigeria.  

Data from several parts of Nigeria point to increasing sexual activity among single adolescents of both sexes with progressive decreasing age at initiation and poor contraceptive use. This paper investigates the sexual behaviour and contraceptive use among teenage secondary school students in Ilesha, southwest Nigeria. This is a cross-sectional population survey of 300 male and female secondary school students within the age group of 13-19 years. The setting is secondary school coaching classes in Ilesha, southwest Nigeria. The outcome measures include prevalence of sexual activity, age at first sexual debut, circumstances leading to first sexual debut, number of sexual partners and family planning use. The result shows that out of the 300 studied, 50% were sexually active, the predominant age at first coitus was 15-19 years, and circumstances leading to sexual debut included mutual agreement, coercion and curiosity. Predominant proportion of sexually active teenagers (86.7%) did not use contraception at the time of first coitus and most of them had more than one sexual partner. The conclusion from this study is that 50% of teenage secondary school girls in this part of Nigeria are sexually active; 68.7% whom, have multiple sexual partners, and 86.7% of them did not use contraception at sexual debut. This unsafe sexual behaviour therefore put them at a great risk of acquiring STDs including HIV infection, and unwanted pregnancy. This study therefore recommends sex education/family life education for young people to encourage them to delay sexual activity as much as possible and practice safe sex when it eventually commences. There is also the need to sensitise the young people, parents, teachers, the community and all stake holders on the magnitude of the problem and to open up dialogue that will break the social, cultural and other mysteries hindering adolescents and youth reproductive health education and services in Nigeria. PMID:16147733

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Water use impact of ethanol at a gasoline substitution ratio of 5% from cassava in Nigeria  

The process of fuel ethanol production from cassava root is connected to a chain of impacts on the water resource of the country where the cassava plant is grown and the root processed into fuel ethanol. The paper assesses the impact of the domestic production of 5 per cent ethanol (E5) needed under the Nigerian biofuel programme from cassava root on the water resource of Nigeria. Using the 2007 Premium Motor Spirit (PMS) consumption as the baseline, Nigeria will require about 0.49 hm{sup 3} of ethanol to blend 9.32 hm{sup 3} of PMS to arrive at the 2007 consumption estimates. The impact of the domestic production of this ethanol requirement translates to about 6.0 km{sup 3} of water; out of which about 48 per cent is green and about 52 per cent is blue. Addressing future impact typical of a developing economy like Nigeria, a three-scenario analysis was adopted to examine the impact of future growth in cassava-fuel ethanol requirement on the water resource of Nigeria, and also, the impact of improved water use on the future water footprint of E5. The projected water impact of cassava-ethanol production into the future ranges from 6.02 to 7.28 km{sup 3}, while improved water use could lower these values by about 0.04-2.35 km{sup 3} for the same period, 2010 to 2020, under the projection assumptions made. (author)

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Progress toward poliomyelitis eradication - chad, january 2011-august 2012.  

In 1988, the World Health Assembly launched the Global Polio Eradication Initiative (GPEI) to interrupt transmission of wild poliovirus (WPV). By January 2012, indigenous WPV transmission had been interrupted in all countries except Afghanistan, Pakistan, and Nigeria. However, importation of WPV caused outbreaks in 29 and reestablished transmission in four, previously polio-free African countries during 2003-2011. Transmission after WPV importation is considered reestablished when it continues for ?12 months; in Chad, transmissions of WPV type 3 (WPV3) and WPV type 1 (WPV1) were reestablished. WPV3 was imported from Nigeria in 2007 and continued to circulate; the latest reported WPV3 case occurred on March 10, 2011. Transmission of WPV1 continued after a WPV1 case was imported from Nigeria in September 2010; the latest reported WPV1 occurred on June 14, 2012. This report updates previous reports and describes polio eradication activities and progress in Chad during January 2011-August 2012, as of October 2, 2012. Five WPV1 cases were reported during January-August 2012, compared with 111 WPV1 cases and three WPV3 cases reported during the same period in 2011. Five circulating type 2 vaccine-derived poliovirus (cVDPV2) cases occurred during July-August 2012. Current progress suggests that Chad could interrupt reestablished WPV transmission in 2012, although limitations in surveillance hamper the ability to detect ongoing transmission. Furthermore, with ongoing endemic WPV transmission in Nigeria, Chad remains at risk for new WPV importations. Efforts to strengthen surveillance and enhance routine and campaign immunization performance will need to continue in Chad to ensure interruption of reestablished WPV transmission, limit circulation after any WPV importation, and interrupt transmission of cVDPV. PMID:23095955

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High prevalence of hepatitis B virus among female sex workers in Nigeria/ Alta prevalência de hepatite pelo vírus B entre trabalhadoras do sexo feminino na Nigéria  

Abstract in portuguese A hepatite pelo vírus B (HBV) é infecção endêmica na Nigéria e constitui problema de saúde pública. A prevalência da infecção HBV em muitos grupos profissionais foi descrito na Nigéria. No entanto, a literatura da infecção HBV entre trabalhadoras do sexo feminino (FSW) na Nigéria é escasso. FSW na Nigéria não são submetidas a um controle preventivo de infecção de HBV. Este estudo avalia a extensão da disseminação de HBV entre FSW na Nigéria. Setec (more) entos e vinte (n = 720) FSW (média de idade = 26,7 anos) foram testadas para antígeno de superfície da hepatite B (HBsAg) pelo método ELISA usando sandwich de duplos anticorpos. A prevalência total de HBV entre o FSW foi 17,1%. FSWs entre as idades de 31-35 anos (20,5%) e abaixo de 10 anos de idade (28%) foram mais afetadas. Esta alta prevalência de doença evitável pela vacinação é inaceitável, portanto, vacinação deste grupo de alto risco de HBV deve ser considerada fundamental. Abstract in english Hepatitis B virus (HBV) infection is endemic in Nigeria and constitutes a public health menace. The prevalence of HBV infection in many professional groups has been described in Nigeria. However, literature on HBV infection among female sex workers (FSW) in Nigeria is scanty. FSW in Nigeria are not subjected to a preventive control of HBV infection. This study assesses the extent of spread of HBV among FSW in Nigeria. Seven hundred and twenty (n = 720) FSW (mean age = 26. (more) 7 years) were tested for hepatitis B surface antigen (HBsAg) by a double antibody sandwich ELISA method. The overall HBV prevalence among the FSW was 17.1%. FSWs between the ages of 31-35 year (20.5%) and those with 'age-at-first-sex' below 10 years of age (28%) were most affected. This high prevalence of a vaccine preventable disease is unacceptable, therefore, vaccination of this high risk HBV reservoir group should be considered worthwhile.

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Climate Change Impacts on Crop Production in Nigeria  

The agricultural sector in Nigeria is particularly important for the country's food security, natural resources, and growth agenda. The cultivable areas comprise more than 70% of the total area; however, the cultivated area is about the 35% of the total area. The most important components in the food basket of the nation are cereals and tubers, which include rice, maize, corn, millet, sorghum, yam, and cassava. These crops represent about 80% of the total agricultural product in Nigeria (from NPAFS). The major crops grown in the country can be divided into food crops (produced for consumption) and export products. Despite the importance of the export crops, the primary policy of agriculture is to make Nigeria self-sufficient in its food and fiber requirements. The projected impacts of future climate change on agriculture and water resources are expected to be adverse and extensive in these area. This implies the need for actions and measures to adapt to climate change impacts, and especially as they affect agriculture, the primary sector for Nigerian economy. In the framework of the Project Climate Risk Analysis in Nigeria (founded by World Bank Contract n.7157826), a study was made to assess the potential impact of climate change on the main crops that characterize Nigerian agriculture. The DSSAT-CSM (Decision Support System for Agrotechnology Transfer - Cropping System Model) software, version 4.5 was used for the analysis. Crop simulation models included in DSSAT are tools that simulate physiological processes of crop growth, development and production by combining genetic crop characteristics and environmental (soil and weather) conditions. For each selected crop, the models were calibrated to evaluate climate change impacts on crop production. The climate data used for the analysis are derived by the Regional Circulation Model COSMO-CLM, from 1971 to 2065, at 8 km of spatial resolution. The RCM model output was "perturbed" with 10 Global Climate Models to have a wide variety of possible climate projections for the impact analysis. Multiple combinations of soil and climate conditions and crop management and varieties were considered for each Agro-Ecological Zone (AEZ) of Nigeria. A sensitivity analysis was made to evaluate the model response to changes in precipitation and temperature. The climate impact assessment was made by comparing the yield obtained with the climate data for the present period and the yield obtainable under future climate conditions. The results were analyzed at state, AEZ and country levels. The analysis shows a general reduction in crop yields in particular in the dryer regions of northern Nigeria.

 
 
 
 
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Progress toward poliomyelitis eradication - Nigeria, january 2011-september 2012.  

In 1988, the World Health Assembly launched the Global Polio Eradication Initiative (GPEI) and, in 2012, declared the completion of polio eradication a programmatic emergency for global public health. To date, wild poliovirus (WPV) cases reported worldwide in 2012 are at historically low levels. Nigeria is one of only three countries with uninterrupted WPV transmission (in addition to Pakistan and Afghanistan) and has been the origin of WPV imported into 25 previously polio-free countries since 2003. This report updates previous reports and describes polio eradication activities and progress in Nigeria during January 2011-September 2012, as of October 30, 2012. The number of reported WPV cases increased from 21 in 2010 to 62 in 2011. During January-September 2012, a total of 99 WPV cases were reported, more than doubling from the 42 cases reported during the same period in 2011. During 2011, a total of 32 circulating vaccine-derived polio virus type 2 (cVDPV2) cases were confirmed; six cVDPV2 cases were confirmed during January-September 2012, compared with 18 cVDPV2 cases during the same period in 2011. Nigeria's 2012 Polio Eradication Emergency Plan includes senior government leadership oversight, new program management and strategic initiatives, an accountability framework, and a surge in human resources to address chronically missed children during supplemental immunization activities (SIAs).* In 2012, indicators of immunization campaign quality show modest improvements; available data indicate gaps in surveillance. Continuing WPV transmission in Nigeria poses an ongoing risk for WPV reintroduction and outbreaks in polio-free countries and is a major obstacle to achieving global eradication. PMID:23134973

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A Survey of Surgical Capacity in Rural Southern Nigeria: Opportunities for Change  

Background Despite growing recognition of the massive surgical burden of disease, unmet need, and disparities in access to care in many African countries, little is known about their capacity to deliver surgical, obstetric, emergency, and anesthetic care, particularly in the rural areas where up to 50 % of the population lives. This study aimed to quantify the surgical capacity of select healthcare facilities in rural southern Nigeria in five key areas: Workforce, Infrastructure, Skill, Equipment, and Supplies. Methods We assessed the surgical capacity of 41 private, rural hospitals in southern Nigeria using the Personnel, Infrastructure, Procedures, Equipment, and Supplies survey tool developed by Surgeons OverSeas. The survey was administered to surgical practitioners during their annua...

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Asthma in Nigeria: Are the facilities and resources available to support internationally endorsed standards of care?  

Objective: The objective of this study was to assess the facilities and resources available to support internationally endorsed standards of asthma care at tertiary hospitals (University teaching, Federal Medical Centre and State specialist Hospitals) in Nigeria. Methods: This cross sectional study was conducted among 68 tertiary hospitals (TH) in Nigeria from June 2009 to December 2009. Structured standards of care questionnaires on asthma based on the Global initiative for asthma (GINA) guideline were completed by physician working in each of the TH. Results: Most TH lacked the services of respiratory physicians, internists, and pediatricians. Available basic infrastructures were asthma clinics (0%), clinic registers (20.6%), and hospital protocol (17.6%), doctor's attendance of asthma C...

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The global distribution of clinical episodes of Plasmodium falciparum malaria.  

Background The assessment of lung function is of considerable importance in the diagnosis of respiratory diseases, normal reference values need to be determined. The peak expiratory flow (PEF) is a simple, reproducible and easily affordable test of lung function which has been used in resource poor countries like Nigeria. A study PEF was carried out in medical students of the University of Maiduguri and the result was compared with various prediction equations calculated in other parts of Nigeria. Methods It was a cross-sectional study involving 255 medical students. Data was collected between March and June 2010 using MicroPeak™ peak flow meter (Micromedical MEI 2A2 Kent) as the instrument. Results There was a statistically significant difference between the measured PEF and the predicted values based on different formulae derived from the different parts of Nigeria. However, the values in females in this study was consistent with the one obtained by one investigator in the north western part of the country. PEF positively correlated with the measured anthropometric parameters and age. Conclusion The result of the study showed that the prediction formulae of Njoku et al and Salisu et al may be used in the assessment of PEF of individuals in this environment; however, further studies with larger sample size may be needed. PMID:15759000

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Orthodontic treatment complexity and need at the University College Hospital, Ibadan, Nigeria, according to the Index of Complexity, Outcome and Need (ICON): A pilot study  

Although occlusal indices have been useful in research, audit, practice management, and quality assurance in clinical orthodontics, complexity of orthodontic cases had not been easy to assess for a long time in clinical practice. This pilot study aimed at assessing the orthodontic treatment need and complexity in a referral orthodontic centre in Nigeria. A retrospective analysis of 56 pre-treatment study models randomly selected from the orthodontic model collection of the University College Hospital, Ibadan, Nigeria was carried out without any bias for age or gender. The index of Complexity, Outcome and Need (ICON) was used as the outcome measure. Descriptive statistics were employed in the data analysis. Forty-seven (83.9%) of the sample needed treatment. Thirty-four (60.7%) cases were classified as difficult or very difficult. Only 1 (1.8%) and 13(23.2%) belonged to the easy and mild categories, respectively. The overall mean ICON score was 67.4±19.6 SD (range 25-104). Considerable proportions of these referred orthodontic cases in Nigeria needed treatment and had treatment complexity comparable to the Caucasians.   

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Source to point of use drinking water changes and knowledge, attitude and practices in Katsina State, Northern Nigeria  

In many Sub-Saharan countries such as Nigeria, inadequate access to safe drinking water is a serious problem with 37% in the region and 58% of rural Nigeria using unimproved sources. The global challenge to measuring household water quality as a determinant of safety is further compounded in Nigeria by the possibility of deterioration from source to point of use. This is associated with the use of decentralised water supply systems in rural areas which are not fully reticulated to the household taps, creating a need for an integrated water quality monitoring system. As an initial step towards establishing the system in the north west and north central zones of Nigeria, The Katsina State Rural Water and Sanitation Agency, responsible for ensuring access to safe water and adequate sanitation to about 6 million people carried out a three pronged study with the support of UNICEF Nigeria. Part 1 was an assessment of the legislative and policy framework, institutional arrangements and capacity for drinking water quality monitoring through desk top reviews and Key Informant Interviews (KII) to ascertain the institutional capacity requirements for developing the water quality monitoring system. Part II was a water quality study in 700 households of 23 communities in four local government areas. The objectives were to assess the safety of drinking water, compare the safety at source and household level and assess the possible contributory role of end users' Knowledge Attitudes and Practices. These were achieved through water analysis, household water quality tracking, KII and questionnaires. Part III was the production of a visual documentary as an advocacy tool to increase awareness of the policy makers of the linkages between source management, treatment and end user water quality. The results indicate that except for pH, conductivity and manganese, the improved water sources were safe at source. However there was a deterioration in water quality between source and point of use in 18%, 12.5%, 27% and 50% of hand pump fitted boreholes, motorised boreholes, hand dug wells and streams respectively. Although no statistical correlation could be drawn between water management practices and water quality deterioration, the survey of the study households gave an indication of the possible contributory role of their knowledge, attitudes and practices to water contamination after provision. Some of the potential water related sources of contamination were poor source protection and location, use of unimproved water source and poor knowledge and practice of household water treatment methods, poor hand washing practices in terms of percentage that wash hands and use soap. Consequently 34 WASH departments have been created at the local government level towards establishment of a community based monitoring system and piloting has begun in Kaita local government area.

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Providing an Avenue for Individual Enhancement: The Challenge for Vocational-Technical Education and Training in Nigeria.  

Nigeria's social and economic conditions at and after independence necessitated changes in educational and employment policy. At independence, in 1960, unification and economic development were necessary to galvanize the country's direction. Control and domination of the economy by foreigners deprived the country of the development of an indigenous labor force. In addition, the education system was not responsive to the country's needs. Changes in the world economy, technology, and politics required Nigerians to be competitive. Nigeria established five efforts to train indigenous workers. The Industrial Training Fund promoted the acquisition of skills. The National Policy on Education stipulated the definitions, aims, and objectives of education. The National Board of Technical Education advised the government on matters concerning education, determined labor needs, established standard skills needed and methods of student assessment, and distributed information. The Structural Adjustment Program increased agricultural production and revived Nigeria's economy. The National Policy on Science and Technology emphasized science and technology in order to transform resources into goods and services. Vocational-technical education and training need to have varying strategies. At the national level, strategies include: (1) quality programs; (2) delivery systems; (3) concept-oriented curriculum; (4) positive image; (5) teacher training; (6) national standards; (7) available funds; and (8) program enhancement. At the international level, strategies include: understanding programs; interaction through conferences, visits, and workshops; and nation building. (16 references and 2 tables are included.) (NLA)

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Predictors of condom-use among young never-married males in Nigeria.  

This study examined the factors that influence condom-use among young never-married males in Nigeria. Such information can help improve the design of a prevention programme for young never-married, especially, males to reduce their vulnerability to sexually transmitted infections (STIs) and HIV/AIDS transmission. Data were derived from the 2003 Nigeria Demographic and Health Survey (NDHS). Analysis of data was restricted to 827 males aged 15-24 years, who had never married or lived together with a woman. Both descriptive and analytical methods were used for assessing the net effects of socioeconomic factors on condom-use. The analysis used logistic regression models for determining the predictors of sexual behaviour and condom-use among young never-married males in Nigeria. About 43% of the study population was sexually experienced, and the use of a condom remained low. One in five reported the use of a condom at sexual debut. Level of education, place of residence in childhood, urban/rural region, religious affiliation, economic status index, and exposure to mass media were associated with sexual experience and use of protective measures. Economic status index and mass-media exposure were associated with the use of a condom by the respondents during their last sex encounter. About two-fifths (43%) of the young unmarried Nigerian men were sexually experienced but the condom-use remained low, thus making this sub-group of Nigerian population highly vulnerable to STIs, including HIV/AIDS. PMID:21766563

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Prevalence of dermatophytic fungal infections in children: a recent study in Anambra state, Nigeria.  

We conducted a recent survey of dermatological fungal infections amongst children in both urban and rural parts of Anambra State in the south-east geographical flank of Nigeria during the period January 2003 to December 2003. Samples were collected from 1624 children with clinically suggestive lesions and also between the ages of 4 and 16. Young children aged 7-11 and 4- 6 years had significantly higher incidences (P Microsporum audouinii was the least in occurrence. We compared our result with a recent study in the northern geographical zone and observed that although incidence of dermatophytoses is higher in northern Nigeria, tinea capitis was the predominant clinical type in both regions. In addition, the etiological agents appear to vary from time to time in their occurrence and the reasons for these observations are discussed. A regular surveillance and assessment of the etiologic agent and its prevalence by medical mycologists is strongly recommended to facilitate monitoring, reduce/prevent transmission and spread of dermatophytes in countries like Nigeria where they constitute a public health problem. PMID:16205973

30

Knowledge and use of HIV counseling and testing services among young persons in Ibadan, Nigeria.  

AIDS is a major public health problem in Nigeria. HIV counseling and testing (HCT) service is an important component of prevention and control programs. Little information is available about young persons' knowledge and use of HCT services in Nigeria. This study assessed knowledge of HIV/AIDS and use of HCT services among secondary school students and apprentices in Ibadan, Nigeria. Data were collected through 16 focus group discussions (FGD) and administration of a 36-item questionnaire to 1,281 randomly selected male and female secondary school students and apprentices aged 15-25 years. The respondents consisted of 54% apprentices and 46% students. Although virtually all respondents were aware of AIDS, only 15.8% of the sample had heard about HCT. Of those who were aware of HCT, 30.1% knew where to access the service. Students had superior knowledge of HCT than apprentices. Only 7% of those aware of HCT had ever taken the test. The percentage of those who had reportedly taken the test ranged from 11.3% of female apprentices to 6.3% of male students, 5.3% of female students, and 5.2% of male apprentices. The barriers identified by FGD participants to use of HCT services are fear of stigmatization, perceived exorbitant cost of testing, lack of knowledge of where HCT service are available, and belief that HCT is meant for only sexually active persons. However, 82.6% of the entire sample expressed the willingness to take HCT if it is provided free of charge, and there is a guarantee of confidentiality of results. Young persons have limited knowledge of HCT and under-utilize this service. Establishment of new HCT centers, promotion activities using the media, and peer education are recommended to increase uptake of this service among young persons in Nigeria. PMID:21576066

31

Knowledge of HIV/AIDS and attitude towards voluntary counseling and testing among adults.  

BACKGROUND: Nigeria has the third highest population of people living with human immunodeficiency virus (HIV). Despite this, the knowledge of HIV/AIDS and uptake of voluntary counseling and testing (VCT) is still low, especially in the rural areas. This study assessed knowledge of HIV/AIDS and attitude towards VCT among adults in a rural community in northern Nigeria. METHODS: A pretested questionnaire was administered on a cross-section of 210 adults in Danbare village, northern Nigeria. Information about knowledge of HIV/AIDS and attitudes toward VCT was elicited among respondents. RESULTS: The majority of respondents (59%) did not know the causative agent of AIDS; however, knowledge of route of disease transmission was high, with 71% and 64% of study participants mentioning sexual activity and unscreened blood transfusion, respectively, as possible transmission routes. Respondents listed avoidance of premarital sex, outlawing prostitution, condom use and screening of blood before transfusion as protective measures. Overall, 58 (27.6%), 80 (38.1%) and 72 (34.3%) of the respondents had good, fair and poor knowledge of HIV/AIDS, respectively. After adjusting for confounders, female gender and formal education remained significant predictors of HIV/AIDS knowledge. Reasons for rejection of VCT included fear of stigma, marital disharmony, incurable nature of the disease and cost of treatment. Formal education, female gender and HIV knowledge significantly predicted positive attitude toward VCT for HIV/AIDS among the study population. CONCLUSION: More than half of the respondents had adequate knowledge of HIV/AIDS, and the majority were willing to have VCT. However, misconceptions, fear, gaps in knowledge and limited access to VCT remain prevalent. Our findings suggest the need to provide health education and scale up VCT services in northern Nigeria by targeting the efforts of international and local development partners to underserved rural areas.

32

Prevalence and correlates of poor medication adherence amongst psychiatric outpatients in southwestern Nigeria  

Objective The aim of this study was to assess the rate of adherence to medications amongst psychiatric outpatients in Nigeria and examine factors associated with medication nonadherence amongst this group. Method Psychiatric outpatients (n=342) from three centres were assessed for medication adherence using the Morisky Medication Adherence Questionnaire. Details regarding sociodemographic variables (age, sex, education, religion, marital status, employment, income, medication cost), illness related variables (diagnosis, duration, number of episodes/admissions, insight, severity of symptoms, mental state, functional status), medication related variables (type, mode of administration, side effect, attitude to medication) and perception related variables (self-stigma, perceived causation and ...

33

Assessment of Postharvest Handling and Quality Control Practices of Rice in North Central Nigeria : A Case Study of Lafia, Nasarawa State  

Demand for rice in Nigeria has been increasing in recent years, and it has now become a food security and cash commodity crop. Rice features regularly on the daily menus of almost all Nigerians, and currently consumption is estimated at about 5 million tonnes annually. Although the country produces over 2 million tonnes of rice each year, representing about half of its rice requirement, research reports indicate that the rice is of poorer quality and grade than imported rice owing to the presence of broken and damaged grains, stones, and other impurities. This has led to low consumer demand for domestic rice. The poor competitive status of the local product in the domestic and international markets is thus discouraging and hampering the development of the rice industry in Nigeria.This study carried out an assessment of the paddy rice processing and quality control methods used in Nigeria. Milled rice samples from selected target areas were analyzed for specific physical and cooking qualities, including head rice yield; ratio of broken, cracked, and damaged grain; foreign matter; whiteness; hardness; cooking time; grain elongation and swelling ratios; and water uptake. The results, which were compared with those obtained from two foreign milled rice samples, showed significantly greater percentages of broken, and damaged grains in rice milled in Nigeria (Lafia 1, Lafia 2, and Assakio) than in those produced and milled in other countries (referred to here as Thailand and Japan) (p<0.05). Head rice yield was significantly lower in domestic rice than in foreign rice (p<0.05. Notably, no foreign matter was found in the Thailand and Japan samples. Mean cooking time for Japan (non-parboiled rice) was about 16 min and between 15 and 23 min for the other (all parboiled) rice. There were no significant differences in grain elongation among the samples, but the swelling ratio was better in the domestic rice samples Lafia 1 and Lafia 2 than in the Thailand and Japan samples. The water uptake value in Thailand (2.07) was significantly greater than that in the domestic rice (1.54 to 1.81) (p<0.05). It is therefore concluded that the methods of postharvest handling in Nigeria produced rice with poor physical quality and average cooking quality, even though the swelling ratio, one of the most important influences on consumer choice, was better in Nigerian rice. There is an urgent need for the Nigerian Government and other stakeholders in the rice value chain to invest in infrastructure, machinery, methodologies, and policies that will improve paddy rice processing capacity and processes and bring about the muc-needed improvement in the quality of Nigerian domestic rice.   

34

Community-directed interventions for priority health problems in Africa: results of a multicountry study/ Interventions sous directives communautaires pour répondre aux problèmes sanitaires prioritaires en Afrique: résultats d'une étude multipays/ Intervenciones dirigidas por la comunidad para problemas sanitarios prioritarios en África: resultados de un estudio multipaís  

Abstract in spanish OBJETIVO: Determinar en qué medida el enfoque de dirección por la comunidad utilizado para combatir la oncocercosis en África podría aprovecharse para implantar efectiva y eficientemente la prestación integrada de otras intervenciones sanitarias. MÉTODOS: Se llevó a cabo un estudio experimental de tres años en 35 distritos de salud entre 2005 y 2007 en siete lugares del Camerún, Nigeria y Uganda. En cada sitio se seleccionaron al azar cuatro distritos de ensayo y (more) un distrito de comparación. Todos los distritos habían establecido programas de tratamiento con ivermectina, y en los distritos de ensayo se incorporaron progresivamente otras cuatro intervenciones de reconocida eficacia -suplementos de vitamina A, uso de mosquiteros tratados con insecticida, tratamiento domiciliario de la malaria y tratamiento breve bajo observación directa de los pacientes con tuberculosis- en un proceso de intervenciones dirigido por la comunidad (IDC). Al final de cada uno de los tres años de estudio se realizaron evaluaciones cuantitativas de la cobertura de las intervenciones y los costos relacionados con los proveedores, así como evaluaciones cualitativas del proceso de IDC. RESULTADOS: Mediante la estrategia de IDC se logró una cobertura significativamente mayor que con otras fórmulas de prestación de servicios en todas las intervenciones a excepción del tratamiento breve bajo observación directa. La cobertura de las intervenciones contra la malaria se más que duplicó. Los costos a nivel distrital de la aplicación de las cinco intervenciones fueron inferiores en los distritos de IDC, pero no se hallaron diferencias de costos en el nivel de los servicios de salud de primera línea. La evaluación del proceso reveló que: (i) el aspecto participativo era importante, (ii) los problemas que afectaron reiteradamente al suministro de material de intervención fueron un gran obstáculo para la aplicación; (iii) las comunidades y los ejecutores de cada comunidad mostraron un firme compromiso con el proceso de IDC; y (iv) los ejecutores de las comunidades estaban más motivados por incentivos intangibles que por incentivos financieros externos. CONCLUSIÒN: La estrategia de IDC, basada en los principios básicos de la atención primaria, es un modelo eficaz y eficiente para la prestación integrada de determinadas intervenciones sanitarias a nivel comunitario en África. Abstract in english OBJECTIVE: To determine the extent to which the community-directed approach used in onchocerciasis control in Africa could effectively and efficiently provide integrated delivery of other health interventions. METHODS: A three-year experimental study was undertaken in 35 health districts from 2005 to 2007 in seven research sites in Cameroon, Nigeria and Uganda. Four trial districts and one comparison district were randomly selected in each site. All districts had establis (more) hed ivermectin treatment programmes, and in the trial districts four other established interventions - vitamin A supplementation, use of insecticide-treated nets, home management of malaria and short-course, directly-observed treatment for tuberculosis patients - were progressively incorporated into a community-directed intervention (CDI) process. At the end of each of the three study years, we performed quantitative evaluations of intervention coverage and provider costs, as well as qualitative assessments of the CDI process. FINDINGS: With the CDI strategy, significantly higher coverage was achieved than with other delivery approaches for all interventions except for short-course, directly-observed treatment. The coverage of malaria interventions more than doubled. The district-level costs of delivering all five interventions were lower in the CDI districts, but no cost difference was found at the first-line health facility level. Process evaluation showed that: (i) participatory processes were important; (ii) recurrent problems with the supply of intervention materials were a major constraint to implementation; (iii) the communities and community implementers were deeply committed to the CDI process; (iv) community implementers were more motivated by intangible incentives than by external financial incentives. CONCLUSION: The CDI strategy, which builds upon the core principles of primary health care, is an effective and efficient model for integrated delivery of appropriate health interventions at the community level in Africa.

35

Qualitative assessment of groundwater from Egbe?Mopa basement complex area, northcentral Nigeria  

The quality of groundwater from the Egbe?Mopa area of the Basement Complex of Nigeria has been assessed. Hydro-geochemical analyses and evaluation studies were conducted on twenty water samples, three from boreholes and seventeen from hand-dug wells. The evaluation involved correlation matrix, multivariate analysis (principal component analysis), and comparing the hydro-geochemical data with various standards. The descriptive statistical tests revealed that the principal controlling processes of the groundwater chemistry are hydrolysis of silicate and sulphide minerals and anthropogenic processes. The anthropogenic sources include domestic wastes, and agricultural activities. Based on the hydro-geochemical data, three hydro-geochemical facies were identified, namely: Ca2+?Mg2+?HCO3 ?, Na+?...

36

Carryover of aflatoxin B/sub 1/ in contaminated substrate corn into Nigerian native beer  

Aflatoxins, the toxic secondary metabolites of Aspergillus flavus and Asp. parasiticus, constitute a serious food contamination problem in Nigeria and have been detected in the blood of healthy rural blood donors and primary liver cancer patients from the Guinea savannah region where traditionally brewed cereal beer is popular. A recent survey of traditional breweries in the Jos metropolis has shown a high incidence of aflatoxin B/sub 1/ contamination of their products. The purpose of this study was to assess the efficiency of the traditional brewing in destroying aflatoxins in mould-infected substrate grains.

37

Oral hygiene measures and the periodontal status of school children  

Abstract: Background:- Tooth brushing and other mechanical cleaning procedures are considered the most reliable methods of effective plaque removal, which is essential for prevention of periodontal diseases. Objective:- To investigate the relationship between oral hygiene practices, socioeconomic status and gingival health in a group of Nigerian children. Methods:- Our study population consisted of 242 randomly selected school children in Ile-Ife, Nigeria. Participants completed a questionnaire on oral hygiene measures, their gingival health was assessed using oral hygiene index (OHI), plaque index (PI) and index of gingival inflammation (GI). Results:- Toothbrushing once daily was the most common practice (52.1%). Toothbrush with a fluoride-containing toothpaste was the most common tooth ...

38

Management of immunization solid wastes in Kano State, Nigeria  

Inadequate management of waste generated from injection activities can have a negative impact on the community and environment. In this paper, a report on immunization wastes management in Kano State (Nigeria) is presented. Eight local governments were selected randomly and surveyed by the author. Solid wastes generated during the Expanded Programme on Immunization were characterised using two different methods: one by weighing the waste and the other by estimating the volume. Empirical data was obtained on immunization waste generation, segregation, storage, collection, transportation, and disposal; and waste management practices were assessed. The study revealed that immunization offices were accommodated in either in local government buildings, primary health centres or community health...

39

Contributions of Environmental Clubs Toward Improved Environmental Programs in Selected Secondary Schools in Ibadan, Nigeria  

The descriptive cross-sectional study assessed contributions of Youth Environmental Scout (YES) clubs toward sustainable environmental programs in selected schools in Ibadan, southwest Nigeria. It involved administration of questionnaires, in-depth interviews and observation checklists and results were analyzed using SPSS 10 software package. Results indicated deplorable state of infrastructure particularly basic amenities like water, excreta disposal, and waste management. Noise pollution was mainly due to vehicular traffic (40, 40%). However, Environmental Awareness (EA) in the three schools studied increased dramatically since the establishment of YES clubs. Waste recycling was found to be significantly associated (p < .001) with the level of environmental awareness. Therefore, hav...

40

Overview of Dam Development in Nigeria  

Abstracts This paper attempts to put together details of dams? development in Nigeria. Case studies of dam-related incidents were highlighted. A typical case study of Kainji dam safety monitoring assessment was analysed and discussed. From the results obtained it is observed that majority of the piezometer plot of the spillway points to improving stability especially from year 2000 to 2001. The data collected and analysed indicated some displacement of about 25?mm. in some blocks, which shows an abnormal behaviour and require need for closer observations. The tape extensometers reading and the rod extensometer were briefly discussed.

 
 
 
 
41

Comparative analysis of Nigerian international oil marketing model (NIOMM) and the models of four selected OPEC members; and a proposed new model for Nigeria  

This study demonstrates that NIOMM has deficiencies and, as a result, has affected the progress of Nigeria's political and socio-economic development. One finding is that Nigeria is beset with ineffective planning, lack of marketing expertise, and inadequate marketing strategies. Other findings show that: (1) the Nigerian oil industry (HOI) is suffering from mismanagement stemming from corruption, tribalism, Federal Character Policy, and lack of dedication and patriotism by the Nigerian workers; (2) there is inefficiency in the Nigerian national petroleum corporation (NNPC) but, at the same time, the inefficiency is partly because of the government policies, conflicts, interference by high government officials and politicians, and the enormous size of the oil industry; (3) oil revenues are improperly utilized; (4) neither the multinational oil corporations (MNOCs) nor multinational corporations (MNCs) are assisting the oil producing nations (OPNs) or developing countries (DCs) in their economic development, and MNOCs and MNCs are interested in profit maximization; and (5) MNCs do not transfer the type of technology that meets the needs of DCs, and sometimes the technology creates problems for DCs which ultimately results into conflicts between MNCs and DCs. The inverse of these problems has been a sine qua non for success in the IOMMs of the four OPEC member, especially in Saudi Arabia.

42

Sexual Risk Behaviors and HIV among Female Sex Workers in Nigeria.  

BACKGROUND:: Female sex workers (FSWs) account for about 20% of new HIV infections in Nigeria. We estimated the change in HIV prevalence and sexual risk behaviors between two consecutive rounds of integrated biological and behavioral surveillance surveys (IBBSS) and determined correlates of HIV transmission among FSWs. METHODS:: In 2007 and 2010, HIV prevalence and risk behavior data on brothel-based (BB) and non brothel-based (NBB) FSWs from the IBBSS were evaluated in 6 Nigerian states. Logistic regression was used to identify correlates of HIV infection. RESULTS:: A total of 2897 and 2963 FSWs were surveyed in 2007 and 2010, respectively. Overall HIV prevalence decreased in 2010 compared to 2007 [20% vs. 33%; peducation [AOR:0.70(0.60 - 0.80)] were less likely to be HIV-positive. CONCLUSION:: Results suggest significant progress in reducing the burden of HIV among FSWs in Nigeria, although low condom use with boyfriends continued to be a potential bridge between FSWs and the general population. Venue-based prevention programs are needed to improve safer sex practices among BB-FSWs. PMID:22918155

43

Pharmacists´ participation in the documentation of medication history in a developing setting: An exploratory assessment with new criteria/ Participación de los farmacéuticos en la documentación del historial de medicación en un país en desarrollo: evaluación exploratoria con nuevos criterios  

Abstract in spanish Objetivo: Evaluar el impacto de la participación de los farmacéuticos en la frecuencia y profundidad de la información registrada en los historiales de medicación en un país en desarrollo como Nigeria. Métodos: El estudio consistió en dos fases: la primera fase fue una evaluación basal transversal de la frecuencia y profundidad de la información registrada en los historiales de medicación por los médicos como casos de muestras sistemáticas de 900 pacientes que (more) se estratificaron de 9 unidades ambulatorias en un hospital universitario en el suroeste de Nigeria. La segunda fase fue un estudio exploratorio que envolvió a 10 farmacéuticos que realizaron entrevistas transversales de historias de medicación a 324 pacientes aleatoriamente seleccionados. Resultados: El 49,2% de los pacientes, cuyo historial de medicación fue documentado en el inicio por los médicos eran mujeres; mientras que el 50,3% de los entrevistados por los farmacéuticos eran hombres. La media (DE) de edad de los hombres y las mujeres con historiales de medicación registrados por los médicos y farmacéuticos era de 43,2 (DE=18,6), 43,1 (DE=17,9) años y 51,5 (DE=17,6), 52,1 (DE=17,4) años, respectivamente. La frecuencia de información registrada en los historiales de medicación por los farmacéuticos fue significativamente más alta para 12 de los 13 componentes (P Abstract in english Objective: To assess the impact of pharmacists´ participation on the frequency and depth of medication history information documented in a developing setting like Nigeria. Method: The study consisted of two phases. The first phase was a baseline cross-sectional assessment of the frequency and depth of medication history information documented by physicians in case notes of systematic samples of 900 patients that were stratified over 9 Medical outpatients Units at a premi (more) er teaching hospital in south western Nigeria. The second phase was an exploratory study involving 10 pharmacists who conducted cross-sectional medication history interview for 324 randomly selected patients. Results: 49.2% of patients, whose medication history were documented at the baseline, by physicians, were males; while 50.3% of patient interviewed by pharmacists were male. Mean age (SD) of males and females whose medication histories were documented by physicians and pharmacists were 43.2 (SD=18.6), 43.1 (SD=17.9) years and 51.5 (SD=17.6), 52.1 (SD=17.4) years respectively. The frequency of medication history information documented by pharmacists was significantly higher for twelve of the thirteen medication history components (P

44

Sexual risk behaviours and HIV knowledge of migrant farm workers in a rural community in Nigeria.  

Migration has been associated with a higher risk of STI/HIV but few studies have assessed the sexual risk behaviour of migrant farm workers in Nigeria. An exploratory survey was conducted to assess the knowledge of HIV/AIDS and sexual risk behaviours of migrant farmers in Saki West Local Government Area, Oyo State, Nigeria. Questionnaires were used to obtain information on socio-demographic and occupational characteristics, knowledge of HIV/AIDS, sexual behaviours and history of STI symptoms. Overall 518 respondents were interviewed, slightly over half were aware of HIV/AIDS; awareness was significantly lower among the females, those aged 15-24 years and those with no formal education. Majority (80.7%) were sexually experienced, the mean age at sexual debut was 19.4 +/- 5.2 years and 18.4 +/- 4.2 years for males and females respectively. Sexual intercourse with multiple sexual partners in the past year was reported by 24.6% (males, 35.7%, versus females, 10.4%, p sexual intercourse with a casual partner was reported by 9.1% (12.8% males versus 4.4% females). Only 18.2% used a condom during the last casual sexual contact. Level of awareness of HIV is unacceptably low and sexual risk behaviours are prevalent among these workers. Appropriate sexual health and HIV prevention interventions should be instituted. PMID:21834265

45

Influence of humic acid derived from composted wastes of Nigeria origin on oxidative and antioxidant status of African mud catfish (Clarias gariepinus).  

The utilization of organic fertilizer, a product of composted organic wastes, is being advocated in Nigeria as a solid waste management alternative. The application of such products near surface water could increase organic matter load of the aquatic environment, thus increasing the humic substance concentration that influence metal speciation and bioavailability in water. In this study, Humic Acid (HA), a major humic substance fraction, derived from composted organic wastes of Nigeria origin was evaluated for effects on the oxidative and antioxidant status of African Mud Catfish (Clarias gariepinus) exposed to different HA (100, 250, 500 and 1000 mg L(-1)) concentrations in static water culture. Lipid peroxidation was estimated via malondialdehyde (MDA) using thiobarbituric acid assay while oxidative stress was assessed spectrophotometrically, via superoxide dismutase (SOD), glutathione (GSH) and catalase (CAT) using standard enzymatic assay techniques. Results showed that treatments increased MDA by 20 to 70% but decreased SOD, CAT and GSH by 10 to 42.56%, 43.62 to 64.09% and 9.84 to 67.68%, respectively. Negative coefficient (r) was obtained for CAT (r = - 0.491; p > 0.10), GSH (r = - 0.551; p > 0.10) versus HA concentration but correlation was positive for MDA (r = 0.998; p = 0.012) and the latter. Study revealed humic acid-mediated oxidative stress and lipid oxidation in the fish. The adverse impact was a function of humic acid concentration and an assessment of heavy metal-humic acid mixture effect on the oxidative and antioxidant status of fresh water fish is recommended. PMID:21313906

46

Evaluation of knowledge base of hospital pharmacists and physicians on herbal medicines in Southwestern Nigeria/ Evaluación del conocimineto de farmacéuticos y médicos sobre plantas medicinales en el suroeste de Nigeria  

Abstract in spanish El uso de plantas medicinales entre los pacientes nigerianos y la tendencia a combinarlas con los medicamentos alopáticos mientras están hospitalizados han ido en aumento. Anteriores estudios muestran que los farmacéuticos comunitarios de Nigeria creen que necesitan más formación para aconsejar pacientes en el uso de sus plantas medicinales. Objetivo: Evaluar el conocimiento, uso, aceptabilidad, actitudes y creencias de los farmacéuticos y médicos de hospital en el (more) Suroeste de Nigeria ante las plantas medicinales/fitoterapia/suplementos dietéticos (PM/FT/SD). Métodos: Se usó un cuestionario de 20 preguntas que incluía 8 de plantas medicinales para evaluar conocimiento de los médicos y farmacéuticos sobre la farmacología de PM/FT/SD. Mediante la prueba exacta de Fischer, se evaluaron los efectos de los datos demográficos tal como edad, sexo, año de graduación, años de experiencia y área de especialización, sobre las puntuaciones obtenidas. El nivel de significación se situó en p Abstract in english The use of herbal medicines among Nigerian patients and the tendency to combine this class of medicines with allopathic drugs while on hospital admission have been on the increase. Earlier studies show that community pharmacists from Nigeria believe that they need more training to counsel patients on their use of herbal medications. Objective: To evaluate knowledge base, use, acceptability, attitudes and beliefs of hospital pharmacists and physicians in South-western Nige (more) ria on herbal products / phytopharmaceuticals /dietary supplements (HP/PP/DS). Methods: A 20-odd questionnaire including an 8-item herbal medicine question was used to assess the knowledge of the physicians and pharmacists in the area of pharmacology of HP/PP/DS. Effects of demographic information such as age, sex, year post graduation, years of experience and area of specialization on the scores obtained were evaluated using Fisher?s exact tests. Level of significance was set at p

47

A Survey of Surgical Capacity in Rural Southern Nigeria: Opportunities for Change.  

BACKGROUND: Despite growing recognition of the massive surgical burden of disease, unmet need, and disparities in access to care in many African countries, little is known about their capacity to deliver surgical, obstetric, emergency, and anesthetic care, particularly in the rural areas where up to 50 % of the population lives. This study aimed to quantify the surgical capacity of select healthcare facilities in rural southern Nigeria in five key areas: Workforce, Infrastructure, Skill, Equipment, and Supplies. METHODS: We assessed the surgical capacity of 41 private, rural hospitals in southern Nigeria using the Personnel, Infrastructure, Procedures, Equipment, and Supplies survey tool developed by Surgeons OverSeas. The survey was administered to surgical practitioners during their annual conference in November 2011. RESULTS: Among the 41 hospitals surveyed, general practitioners (52.1 %) constituted most of the surgical workforce. Only one anesthesiologist was available in 16 secondary hospitals. Although most of the primary and secondary hospitals had running water (82.3 %), a designated emergency room (80.5 %), and medical records (95.9 %), only 50.3 % of all hospitals had electricity through the power grid. Also, only 37.5 % of all facilities had a blood bank and 43.8 % had an X-ray machine. Common surgical procedures were done by most of the facilities; however, cricothyroidotomy, clubfoot repair, and obstetric fistula repair were scarcely done. Less than half of the facilities provided general anesthesia, only 20 % have an anesthesia machine, and 44.5 % have a pulse oximeter. CONCLUSION: Severe shortages in key areas should motivate stakeholders to devote more effort and resources to strengthening surgical capacity in rural southern Nigeria. PMID:22955951

48

A simple method for rapid community assessment of tungiasis  

Summary Objective To evaluate a rapid assessment method to estimate the overall prevalence of tungiasis and severity of disease in endemic communities. Methods We analysed data from 10 population-based surveys on tungiasis, performed in five endemic communities in Brazil and Nigeria between 2001 and 2008. To assess the association between occurrence of tungiasis on six defined topographic areas of the feet and the true prevalence/prevalence of severe disease, linear regression analyses were performed. Estimated prevalences were calculated for each of the 10 surveys and compared to true prevalences. We then selected the most useful topographic localization to define a rapid assessment method, based on the strength of association and operational aspects. Results In total, 7121 individuals of...

49

Cenomanian-Turonian organic facies in the western Mediterranean and along the adjacent Atlantic margin  

Pre-Cenomanian sediments of the western Mediterranean and adjacent Atlantic margin are characterized by low total organic content (TOC) with an important terrestrial component. During the Cenomanian, TOC increased and the marine component became dominant, culminating around the Cenomanian-Turonian boundary with TOC up to 40%. After the Turonian, organic-rich sediments progressively disappeared and were replaced by more oxygenated sediments. Study methods include considering data from outcrops, DSDP/ODP sites, or petroleum wells. Detailed data from onshore locations allowed the development of high-resolution stratigraphy, analysis of depositional environment, and calculation of sedimentation rates. Analysis of these data indicates Cenoamnian-Turonian organic-rich sediments can be observed in a wide range of bathymetric settings. They are widespread in the western Mediterranean and Atlantic and have been especially studied in Italy (Apennines, southern Alps), Tunisia (Bahloul), Algeria, Morocco (Rif Mountains, Atlas Mountains, Tarfaya), Gibraltar arch, Spain (Betics, Bay of Biscay, Galicia margin), Senegal (Cape Verde basin, Casamance), and Nigeria (Benue, Calabar flank).

50

Molecular epidemiology of rotavirus and norovirus in Ile-Ife, Nigeria: High prevalence of G12P[8] rotavirus strains and detection of a rare norovirus genotype  

Abstract Rotavirus (RV) and norovirus (NoV) are considered the most common causes of viral gastroenteritis in children. In this study, the prevalence of RV and NoV infection in 55 children with diarrhea from the rural community Akinlalu in Southwestern Nigeria was investigated using real-time PCR assays. The RV and NoV strains were genotyped by PCR and/or sequencing. RV and NoV infections occurred with a prevalence of 34.5% and 25.5% respectively, with predominance in children <1 year. Most infections occurred during the dry season with increasing prevalence of RV as the dry season progressed (October-January). Infections with RV VP6 subgroup (SG) II were more prevalent (27.3%) than SGI (7.3%). Similarly, NoV genogroup II infections were more common (23.6%) than genogroup I (1.8%). Five ch...

51

Material flows of mobile phones and accessories in Nigeria: Environmental implications and sound end-of-life management options  

Presently, Nigeria is one of the fastest growing Telecom markets in the world. The country's teledensity increased from a mere 0.4 in 1999 to 10 in 2005 following the liberalization of the Telecom sector in 2001. More than 25?million new digital mobile lines have been connected by June 2006. Large quantities of mobile phones and accessories including secondhand and remanufactured products are being imported to meet the pent-up demand. This improvement in mobile telecom services resulted in the preference of mobile telecom services to fixed lines. Consequently, the contribution of fixed lines decreased from about 95% in year 2000 to less than 10% in March 2005. This phenomenal progress in information technology has resulted in the generation of large quantities of electronic waste (e-waste)...

52

Potential groundwater contamination with toxic metals around refuse dumps in some parts of Lagos metropolis, Nigeria  

Industrial evolution in developing countries, most especially Nigeria in the last century, has resulted in geometrical increase in waste generation compared to the arithmetic progress in management methods, thereby creating the problem of effective waste management and disposal. Wastes generated from industries have become a major source of pollution of groundwater when contaminants become leached into the groundwater. Water samples collected from 44 wells within 25 m radius from six refuse dump sites within Lagos metropolis during the months of February and September, 2006 were analyzed for nine heavy metals, namely, Lead (Pb), Chromium (Cr), Zinc (Zn), Cadmium (Cd), Nickel (Ni), Cobalt (Co), Iron (Fe), Manganese (Mn) and Copper (Cu), using AAS according to standard procedures. The result...

53

High prevalence of BRCA1 and BRCA2 mutations in unselected Nigerian breast cancer patients.  

Inherited mutations in the BRCA1 and BRCA2 genes are the strongest genetic predictors of breast cancer and are the primary causes of familial breast/ovarian cancer syndrome. The frequency, spectrum and penetrance of mutant BRCA1/BRCA2 alleles have been determined for several populations, but little information is available for populations of African ancestry, who suffer a disproportionate burden of early onset breast cancer. We have performed complete sequence analysis of all BRCA1 and BRCA2 exons and intron-exon boundaries for 434 Nigerian breast cancer patients from the University College Hospital in Ibadan, Nigeria. In contrast to previous suggestions that BRCA1/BRCA2 mutation frequencies are low or undetectable in African American populations, we find that Nigerian breast cancer patients have an exceptionally high frequency of BRCA1 and BRCA2 mutations (7.1 and 3.9%, respectively). Sixteen different BRCA1 mutations were detected, seven of which have never been reported previously, while thirteen different BRCA2 mutations were seen, six of which were previously unreported. Thus, our data support enrichment for genetic risk factors in this relatively young cohort. To improve breast cancer outcomes, we suggest that family-based models of risk assessment and genetic counseling coupled with interventions to reduce breast cancer risk should be broadly disseminated in Nigeria and other underserved and understudied populations. PMID:22034289

54

Using drama for school-based adolescent sexuality education in Zaria, Nigeria.  

This paper describes the use of drama and participatory methods in a girls-only secondary school in Zaria, Nigeria, as a means of sexuality education, carried out by the Nigerian Popular Theatre Alliance and the Second Chance Organization of Nigeria. The issues addressed had to come from the students, to allow them to develop critical thinking and learn useful lessons. The topics that concerned the group of 15 girls who participated from the school included abortion, premarital sex and pregnancy, teacher-student relationships and lesbianism. Participants developed a play about teacher-student relationships and presented it to the whole school. The presentation was stopped several times in order to involve the audience in discussing the choices available to the protagonist and what they would do in her place. This allowed all the students to explore the problem, generate and assess alternative solutions and communicate their learning to others. It also started a process of change in how the school dealt with girls who were forced to drop out due to sexuality-related problems, including pregnancy. Our long-term aim is advocacy to support the introduction of sexuality education as a permanent element in the curriculum throughout the school system. PMID:18513621

55

Bulk H analysis using neutrons for routine quality control of cassava and products  

Nuclear and related techniques are useful in addressing the issues of food security and safety facing the world today, via quality control of raw materials and products. In this work, experimental investigations were performed to assess the use of total hydrogen content in cassava and products as a quality control indicator of starch and cyanide contents. The work was carried out using a neutron reflection facility at the Centre for Energy Research and Training, Ahmadu Bello University, Zaria, Nigeria. Cassava samples and products were obtained from retail outlets of Ibadan, Umudike and Zaria, representing three major regions of Nigeria. In general, data obtained indicate a total hydrogen content range of 4.47{+-}0.11-10.71{+-}0.27 wt% for the various samples, including raw, dry and processed cassava. Results show that samples having low hydrogen content are generally rich in cyanide compounds and demonstrate an inverse relationship between hydrogen content and cyanide content. The implication of this is that the neutron reflection facility can be used as a quality control setup for routine determination of hydrogen as an indicator of the cyanide content in cassava and products.

56

Medication adherence among ambulatory patients with type 2 diabetes in a tertiary healthcare setting in Southwestern Nigeria/ Adherencia a la medicación entre pacientes con diabetes tipo 2 en establecimientos sanitarios terciarios en el suroeste de Nigeria  

Abstract in spanish Objetivo: Evaluar la adherencia a la medicación entre pacientes ambulatorios con diabetes tipo 2, determinar el nivel de control glucémico, y evaluar las opiniones de los pacientes sobre las probables razones de la no adherencia con vista a identificar áreas de intervención en la mejora del cumplimiento. Métodos: Se realizó un estudio prospectivo transversal en un hospital universitario terciario de 900 camas en Ibadan, Suroeste de Nigeria, entre junio y agosto de 2 (more) 009. De los 140 pacientes que consintieron, 114 (81,4%) respondieron correctamente al instrumento validado y pre-testado de recogida de datos y fueron consiguientemente analizados. Se usó estadística descriptiva para resumir los datos. Las medias y proporciones se compararon usando t de Student y chi cuadrado o test de Kruskal-Wallis, con p Abstract in english Objective: To assess adherence to medication among ambulatory patients with type 2 diabetes, ascertain the level of glycemic control, and evaluate patients´ opinions on probable reasons for non-adherence with a view to identify areas of intervention to improve adherence. Methods: A prospective cross-sectional study was carried out at a 900-bed tertiary teaching hospital in Ibadan, Southwestern Nigeria between June and August, 2009. Out of 140 consented patients, 114 (81. (more) 4%) properly responded to the validated and pre-tested data collection tool and these were subsequently considered for analysis. Descriptive statistics were used to summarize the data. Means and proportions were compared using student t-test and chi-square or Kruskal-Wallis test as appropriate, with p

57

Ecological integrity of upper Warri River, Niger Delta using aquatic insects as bioindicators  

Aquatic insects are bioindicators of water quality. Their structure and species composition is used in assessing the ecological integrity of streams and rivers. Their composition and density of the upper Warri River, Niger Delta, Nigeria were assessed and the influence of different physical and chemical variables on their distribution was explored at three designated stations. A total of 57 taxa were recorded with station 2 accounting for the greatest Ephemeroptera-Plecoptera-Trichoptera (EPT) richness. Abundance of the aquatic insects was affected by the nature of the substrate, macrophytes and canopy cover at the various stations examined. Generally, the upper Warri River is a fairly clean water body rich in EPT organisms. Pollution tolerant insect taxa such as chironomids and culicids l...

58

Characterization of colorectal symptoms in women with vesicovaginal fistulas  

Objective: To characterize colorectal symptoms in women with a history of an obstetric vesicovaginal fistula (VVF). Methods: Patients under evaluation with a VVF during two 2-week surgical service trips to Evangel Hospital VVF Center in Jos, Nigeria, in 2010 were assessed for symptoms of fecal incontinence (FI) using the Vaizey and Colorectal-Anal Impact (CRAIQ) questionnaires. Women with rectovaginal fistulas were excluded. Each participant's impression of overall health was assessed using a visual analog scale (VAS) from 0 (poor) to 15 (excellent). A study nurse translated questionnaires into native languages. Results: The mean age of the 83 women included was 29years. Three women (3.6%) reported FI and 42 (50.6%) reported constipation. All of the women with FI reported that it affected ...

59

Itinerant vending of medicines inside buses in Nigeria: vending strategies, dominant themes and medicine-related information provided/ Venta itinerante de medicamentos en autobuses en Nigeria: estrategias de venta, temas dominantes e información sobre medicamentos proporcionada  

Abstract in spanish Objetivo: Determinar las estrategias de venta y los temas de marketing empleados por los vendedores en autobuses itinerantes y evaluar la precisión y compleción de la información sobre medicamentos proporcionada durante la venta en un área urbana de Nigeria. Métodos: Estudio transversal y análisis de contenido de la venta itinerante de medicamentos en autobuses grabadas con un teléfono móvil en rutas seleccionadas a propósito en una mega-ciudad de 18 millones de (more) habitantes en el suroeste de Nigeria durante un periodo de dos meses. Dos codificadores evaluaron independientemente 192 episodios de venta de 56 vendedores para 147 medicamentos OTC y de prescripción. Fiabilidad inter-evaluador (K de Cohen)=0.89 [IC95% 0.76-0.92]. Resultados: 14.400 potenciales consumidores visitaron los 192 episodios grabados de venta de medicamentos en el interior de 192 autobuses en el periodo de estudio. 44 (78.5%) de los 56 vendedores eran mujeres entre los 30-45 años, estaban mayoritariamente (75%) con tejidos tradicionales "Iro and Buba" Ankara y mostraban tarjetas identificativas plastificadas (97.5%) emitidas por las autoridades locales para "vendedores" de medicamentos en autobuses, mercados y aparcamientos. De los 14.400 consumidores que visitaron el interior de los buses durante el periodo de estudio, el 6.7% y el 48.3% compró los medicamentos promocionados. Oraciones contra la muerte en accidentes de tráfico y enfermedades de orígenes físicos o metafísicos eran los mensajes para romper el hielo / estrategias para ganar la atención de los clientes más frecuentemente utilizados (76.8%). Los medicamentos más frecuentemente vendidos eran los hematínicos, multivitamínicos, analgésicos simples, AINE y corticoides. Las preguntas de los consumidores estaban relacionadas con las dosis para niños (51.8%), ancianos (28.6%) y embarazo (52.7%); y contraindicaciones durante el embarazo (8.9%). En la mayoría de los episodios de venta no se proporcionaba informaciones objetivas sobre los medicamentos, como dosis, frecuencia, efectos adversos potenciales y contraindicaciones. Conclusión: La venta itinerante de medicamentos y el uso de temas engañosos y melodramáticos para asegurar el elevado consumo aparecen frecuentemente en Nigeria. La mayoría de los vendedores no respondió correctamente a las preguntas sobre medicamentos de los consumidores, ni proporcionó información objetiva detallada para guiar en el uso adecuado. Estas actividades promocionales engañosas probablemente podrían animar a la compra y a la automedicación de los consumidores. Abstract in english Objective: To determine vending strategies and marketing themes employed by itinerant bus vendors, and assess the accuracy and completeness of information provided on medicines being sold in an urban setting in Nigeria Methods: Cross-sectional study and content analysis of itinerant vending of medicines inside buses recorded with a mobile telephone on purposively selected routes in a mega city with an estimated 18 million residents in southwestern Nigeria over a 2-month p (more) eriod. Two coders independently assessed 192 vending episodes by 56 vendors for 147 OTC and prescription medicines. Inter-rater reliability (Gwet AC1 =0.924; p

60

Changing Patterns of Access to Education in Anglophone and Francophone Countries in Sub Saharan Africa: Is Education for All Pro-Poor? CREATE Pathways to Access. Research Monograph No. 52  

This paper explores patterns of growth in participation in six Anglophone and seven Francophone countries in SSA. The countries are Kenya, Malawi, Nigeria, Tanzania, Uganda, Zambia, Benin, Burkina Faso, Cameroon, Madagascar, Mali, Niger and Senegal. These countries all have large scale Universal Primary Education programmes and all have demographic and health survey (DHS) data sets collected at least ten years apart. These allow comparisons over time to see how participation has been changing. The results show that progress has been patchy and sometimes disappointing. Access remains strongly associated with household wealth despite commitments to pro-poor policies. The chances of the poorest being enrolled relative to the richest have generally not improved substantially, and in some cases have deteriorated. Reductions in numbers of out of school children have in some cases been accompanied by increases in the proportion over age. Poorer children and rural children are more likely to be over age and unlikely to complete schooling, especially if they are girls. The message is clear. Though there has been progress, it falls far short of the gains that were anticipated. Much more progress is needed to achieve universal access with equity and to close the gap between the poorer and richer households. (Contains 9 tables and 13 figures.)

 
 
 
 
61

Paediatricians' perspectives on global health priorities for newborn care in a developing country: a national survey.  

ABSTRACT: BACKGROUND: An understanding of the perception of paediatricians as key stakeholders in child healthcare delivery and the degree of congruence with current investment priorities is crucial in accelerating progress towards the attainment of global targets for child survival and overall health in developing countries. This study therefore elicited the views of paediatricians on current global priorities for newborn health in Nigeria as possible guide for policy makers. METHODS: Paediatric consultants and residents in the country were surveyed nationally between February and March 2011 using a questionnaire requiring the ranking of nine prominent and other neonatal conditions based separately on hospital admissions, mortality, morbidity and disability as well as based on all health indices in order of importance or disease burden. Responses were analysed with Friedman test and differences between subgroups of respondents with MannWhitney U test. RESULTS: Valid responses were received from 152 (65.8%) of 231 eligible physicians. Preterm birth/low birthweight ranked highest by all measures except for birth asphyxia which ranked highest for disability. Neonatal jaundice ranked next to sepsis by all measures except for disability and above tetanus except mortality. Preterm birth/low birthweight, birth asphyxia, sepsis, jaundice and meningitis ranked highest by composite measures while jaundice had comparable rating with sepsis. Birth trauma was most frequently cited under other unspecified conditions. There were no significant differences in ranking between consultants and residents except for birth asphyxia in relation to hospital admissions and morbidity as well as sepsis and tetanus in relation to mortality. CONCLUSIONS: Current global priorities for neonatal survival in Nigeria largely accord with paediatricians' views except for neonatal jaundice which is commonly subsumed under miscellaneous neonatal conditions. While the importance of these priority conditions extends beyond mortality thus suggesting the need for a broader conceptualisation of newborn health, paediatricians should be actively engaged in advancing the attainment of global priorities for child survival and health in this population. PMID:22748076

62

Skills Mismatch among University Graduates in the Nigeria Labor Market  

University graduates in Nigeria have been reported to be poorly prepared for work in recent years. This has implications on the relevance of university education, the employability and productivity of university graduates. One of the reasons suggested for this condition by previous studies was skill mismatch--a situation where there is a disparity between the skills acquired by students in the universities and the actual skills needed in the labor market. However, not many of these studies have investigated the extent of skill mismatch in Nigeria. This study, therefore, examined the problem of skills mismatch and its prevalence in the Nigeria labor market. The study adopted the descriptive survey research design of "ex-post facto" type. The research was carried out in all the six geo-political zones of the country. Purposive sampling technique was used to select one town per geo-political zone. A total of 600 management staffs were randomly selected for the study. A set of questionnaire titled "Labor Market Demands and Employers Assessment Questionnaire" (r = 0.83) was utilized to elicit relevant information from employers of labor on the current labor market skill demands and their assessment of the performance of recently employed university graduates in 300 organizations (from both private and public sectors). Three research questions were answered and two hypotheses were tested at the significant level of 0.05. Data were analyzed using descriptive statistics, ANOVA (analysis of variance) and t-tests. There was a significant negative relationship between skills demand and supply (r = -0.485; p less than 0.05). The extent of skills mismatch was 60.6% with major weaknesses found in communication, IT (information technology), decision-making, critical thinking and entrepreneurial skills. Analytical skill was the most required skill by the labor market and critical thinking the least. The mean for each of the skills demand was significantly different from its supply. University graduates were not adequately prepared for work with respect to skills demand of the labor market. Nigerian universities are therefore enjoined to inculcate the skills identified as critical but deficient in the graduates. Also, parents should understand the skills demand of the labor market in order to guide their wards appropriately. (Contains 6 tables.)

63

Effects of Space Radiation on Hippocampal ... - HRR - Task  

... Evaluate the potential of SR to accelerate Alzheimer's disease pathogenesis and ... susceptibility including hereditary pre-disposition (Alzheimer's, Parkinson's , ..... Precise Assessment of Prevalence and Progression of Lens Opacities in ...

64

National Institute for Petroleum and Energy Research quarterly technical report, April 1--June 30, 1992. Volume 2, Energy production research  

Progress reports are presented for: chemical flooding--supporting research; gas displacement-supporting research; thermal recovery-supporting research; geoscience technology; resource assessment technology; and microbial technology. (AT)

65

National Institute for Petroleum and Energy Research quarterly technical report, April 1--June 30, 1992  

Progress reports are presented for: chemical flooding--supporting research; gas displacement-supporting research; thermal recovery-supporting research; geoscience technology; resource assessment technology; and microbial technology. (AT)

66

Children and marital satisfaction in a non-Western sample: having more children increases marital satisfaction among the Igbo people of Nigeria  

Previous research has demonstrated that having more children decreases marital satisfaction among parents. However, the universality of these findings is limited since the vast majority of the studies have been conducted in Western countries. In the present study, 374 people from the Igbo ethnic group (Nigeria) were assessed for levels of marital satisfaction and the number of children. In contrast to almost all previous findings, we found a positive relationship between the number of children and marital satisfaction among parents. Number of children was the strongest predictor of marital satisfaction even when compared to other variables like wealth and education. Our results suggest that the negative relationship between the number of children and marital satisfaction is not culturally ...

67

Incidence of dog bite and anti-rabies vaccine utilization in the, University of Benin Teaching Hospital, Benin City, Nigeria: A 12-year assessment  

Aim: To assess the incidence of dog bite and utilization of anti-rabies vaccine between January 1997 and December 2008. Methods: Reported cases of dog bite from archives were collected and analyzed in the Accident and Emergency Centre of the University of Benin Teaching Hospital, Benin City, Nigeria. Result: A total of 143 cases were reported and none was previously immunized. They were between 14 and 64 years with male and female ratio 7.2:1. Among them, 53% cases were reported within 24h, 36% cases were reported after 30 days and 11% cases reported after two months of affliction. Limbs were most afflicted. Forty-two [29.37%] patients had multiple sites of bite. Minor bleeding was in [71.33%] victims. Five hundred and eighty-seven doses of Rabipur brand of anti-rabies vaccines of which 65...

68

Mineral and trace element composition of the Lokpanta oil shales in the Lower Benue Trough, Nigeria  

The concentrations of minerals and trace elements in the Lokpanta oil shale from the Lower Benue Trough, Nigeria have been determined by X-ray diffraction (XRD) and laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS), respectively. X-ray diffraction data were evaluated using the SIROQUANT interactive data processing system based on Rietveld interpretation methods. A new method of trace element determination in oil shale, involving LA-ICP-MS analysis of glass beads prepared by fusing oil shale ash on an iridium strip heater was used, and the accuracy of the method was assessed by including a standard shale reference material (SGR-1b) in the analysis program. The minerals in the raw oil shales are mainly quartz, calcite and clay minerals, with the latter being represented...

69

Urban transport safety assessment in akure based on corresponding performance indicators  

The level of safety of the transportation system in Akure, Nigeria was assessed by identifying the associated road safety problems and developing the corresponding safety performance indicators. These indicators were analysed with respect to accidents that occurred within the city from the year 2005 to 2009 based on the corresponding attributable risk measures. The results of the analysis showed the state of existing safety programs in Akure town. Six safety performance indicators were identified namely alcohol and drug use, excessive speeds, protection system (use of seat belts and helmets), use of day time running lights, state of vehicles (passive safety) and road condition. These indicators were used to determine the percentage of injury accidents as follows: 83.33% and 86.36% for years 2005 and 2006 respectively, 81.46% for year 2007 while years 2008 and 2009 had 82.86% and 78.12% injury accidents respectively.

70

Prenatal care and basic emergency obstetric care services provided at primary healthcare facilities in rural Nigeria  

Objective: To assess the availability of prenatal care and basic emergency obstetric care services at primary healthcare (PHC) facilities in rural Nigeria. Methods: In total, 652 PHC facilities enrolled in the Midwives Service Scheme, a government-funded program designed to reduce the national shortage of skilled birth attendants, were surveyed. Results: In all, 44.0% of the PHC facilities evaluated did not provide all components of prenatal care, and only 39.0% of all pregnant women nationwide attended prenatal care clinics 4 or more times. In addition, 52.2% of the facilities were not distributing insecticide-treated nets to pregnant women, while only 36.8% of the PHC facilities provided services to prevent mother-to-child transmission of HIV. By contrast, 70.0% of the PHC facilities had...

71

Endotoxin-induced coagulation reactions and phenoloxidase activity modulation in Sudanonautes africanus hemolymph fractions  

Sudanonautes africanus is a freshwater crab local to Nigeria and West Africa that has no documentation of its innate immunity reactions. The objective of this study was to assess the effect of endotoxin (lipopolysaccharide [LPS]) on coagulation and on phenoloxidase (PO) activity in the hemolymph fractions of S. africanus. The hemolymph from each of 10 live crabs was obtained by carapace puncture and then fractionated into plasma and hemocytes. The hemocytes were then processed and then fractionated into hemocyte lysate (HL), hemocyte lysate supernatant (HLS), and hemocyte lysate debris (HLD). In one study, each fraction was then incubated with a fixed level of LPS in the presence or absence of exogenous calcium (Ca2+) ion. In another study, the LPS concentration was varied in order to stud...

72

A Mixed Methods Approach to Vulnerability and Quality of Life Assessment of Waste Picking in Urban Nigeria  

Quality of life (QoL) studies have become acceptable globally as indicators of how well a people are living. They are increasingly being used to identify and design areas of intervention to raise the wellbeing of a population. While studies on livelihoods in the informal waste recycling system of developing country cities have also been on the increase in recent years, assessments of the QoL expectations within the livelihoods framework in the informal waste recycling sector seem surprisingly few. Studies of this nature have also not been undertaken in the context of Nigerian socio-political, cultural and economic environment. Applying qual-dominant mixed methods approach to the livelihood activity of waste picking in the commercial city of Aba in southeastern Nigeria, this paper identifie...

73

Stimulation of investment in international energy through Nigerian tax exemption laws  

This article assesses the impact of recent tax exemption legislation as a vehicle for the attraction of investment in the quest for the development of international energy in Nigeria, particularly oil and gas. It seeks to argue that generous tax incentives are the most successful method of inducement of foreign investors, judging from the rising profile in the expansion of investment in the gas sector and the attendant increase in world trade. It attempts to assert that tax incentives alone, without the combination of other favourable factors, like political stability, observance of the rule of law and deregulation or trade liberalisation, cannot produce the desired result of local industrialisation and integration into the world economy. (author)

74

Endogenous antioxidant defences in plasma and erythrocytes of pregnant women during different trimesters of pregnancy  

Background. To assess the antioxidant capacity of pregnant women in Ogun State, Nigeria. Methods. The activities of total superoxide dismutase (total SOD), manganese superoxide dismutase (Mn-SOD), catalase (CAT), glutathione transferase (GST), aminolevulinic acid dehydratase (ALAD), and the concentrations of glutathione (GSH), were determined in the plasma and red blood cells of non-pregnant (n=20), normal healthy pregnant women during different trimesters of pregnancy (n=90), and pregnant women with pre-eclampsia (n=7). Results. A 2-fold increase in erythrocyte CAT activity was observed in the pregnant women (p<0.05), while CAT activity in the pre-eclamptic women was not significantly different from control (p>0.05). A 3-fold increase in plasma Mn-SOD was observed in the pregnan...

75

Climate change and energy implications of gas flaring for Nigeria  

The flaring of oil-associated gas continues to generate insidious environmental and energy consequences against efforts toward sustainable development for Nigeria. This study compared some of the economic benefits lost due to flared gas at flow stations with fuelwood energy consumption. The objectives were to assess comparative cost suffered by host communities, estimate greenhouse gases emissions of burnt-off gas and evaluate possible effects of post-global financial meltdown support policies on climate change. Parameters for evaluating the environmental and energy impacts were measured directly or collected from flow stations through opinion surveys and meetings. An inventory of the motors, voltages and power ratings of the machines used at the flow stations was made, with a view to quan...

76

Administration of 400mg of misoprostol to augment routine active management of the third stage of labor  

Objective: To assess the effectiveness and safety of the administration of misoprostol, an orally active prostaglandin, in addition to routine uterotonic therapy as part of the active management of the third stage of labor. Methods: The present study was a hospital-based, decentralized, multi-center, randomized, placebo-controlled, double-blind trial. We enrolled 1103 women (out of a target sample size of 1180) at 4 hospitals in South Africa, Uganda, and Nigeria. Participants received a sublingual dose of 400mg of misoprostol or a placebo, in addition to standard active management of the third stage of labor, after vaginal birth. Results: The baseline characteristics of the participants were comparable. The difference in the primary outcome of blood loss of 500mL or more within 1 hour of r...

77

Seed sorting of sesame (Sesamum indicum L.) by salt density and seed-borne fungi control with plant extracts  

The effectiveness of sesame seed sorting by salt density and seed-borne fungi control by plant extracts was evaluated in Abeokuta, Nigeria. Seeds of two sesame cultivars (530-6-1 and NCRIBEN-03L) were soaked in 2%, 5%, 10% and 15% salt (NaCl) concentrations, separated as floated or sunken (immersed) seeds and assessed on blotter medium for fungal infection and viability. The effects of extracts of leaves of Azadirachta indica, Vernonia amygdalina, Musa paradisiaca and Anacardium occidentales as well as synthetic fungicides, Team (Carbendazin 12% + Mancozeb 63%) and Ridomil (Metalaxyl 60g + 60 g CuO2) on seed infection by fungi, seed germination and seedling emergence was also evaluated. Unsorted (untreated) seeds served as control. Results showed that 10% and 15% salt c...

78

The effect of post-cesarean rectal misoprostol on intestinal motility  

Objective: To determine whether rectally administered misoprostol can induce intestinal motility compared with oxytocin infusion when used to prevent primary postpartum hemorrhage after cesarean delivery. Methods: In a prospective randomized double-blind study in Nigeria, 218 parturients undergoing cesarean delivery who had risk factors for primary postpartum hemorrhage were enrolled between July 1, 2010, and March 31, 2011. Participants received 600mg of rectal misoprostol or 20 intravenous units of oxytocin for 4hours after surgery. The primary outcome was time until passage of flatus. Adverse effects, need for additional analgesic, and length of hospital stay were also assessed. Results: The misoprostol group had a significantly shorter mean postoperative interval to passage of flatus (...

79

The impact of internet use on teaching, learning and research activities in Nigerian universities: A case study of Obafemi Awolowo University  

Purpose - The purpose of this paper is to assess the impact of internet resources and the evaluation of their usefulness on teaching, learning and research in Nigerian universities with particular emphasis on Obafemi Awolowo University (OAU), Ile-Ife, Osun State, Nigeria. Design/methodology/approach - The paper is based on a descriptive survey using questionnaires for data collection. The respondents constitute students (750) and academic staff (115) from OAU. Descriptive statistics (frequency counts and percentages) were used to analyze the data. Findings - The results from the paper reveal that a majority of the surveyed academic staff and the students found the internet to be very useful. Internet resources mostly used by both groups were e-mail and the world wide web (WWW). Search inte...

80

Effects of lime on the herbicidal efficacy of atrazine and yield response of maize (Zea mays L.) under field conditions in southwestern Nigeria  

Soil acidity or alkalinity is known to affect the persistence of some herbicides, which in turn could affect the duration and effectiveness of weed control. A randomized complete block field experiment was conducted over 2 years to evaluate the effect of lime on the herbicidal efficacy of atrazine applied at the recommended dose of 3.0kga.i.ha-1 or in combination with preplant soil-incorporated application of lime at 0.5, 1.0, 1.5 and 2.0tha-1 in a maize crop at the Teaching and Research Farm of the Federal University of Technology, Akure (7degree16primeN, 5degree12primeE), Nigeria. Assessment of herbicidal efficacy based on the Henderson-Tilton formula indicated that atrazine applied singly or in combination with varying rates of lime proved highly effective in controlling most of the bro...

 
 
 
 
81

Waste yield, proximate and mineral composition of three different types of land snails found in Nigeria.  

Some aspects of the chemical and anatomical weight composition of land snails in Nigeria were analysed with a view to assessing the waste yield, carcass yield and their nutritional evaluation on wet weight basis. Proximate analysis of Archachatina, Archatina and Limicolaria species was carried out on the carcass. Moisture and protein contents were high in all samples, fat and ash contents were generally low while crude fibre was not detected. The concentrations of iron, copper, zinc, manganese, sodium, calcium, magnesium, potassium and cobalt were determined in the carcass. Values of iron, calcium, magnesium, sodium and potassium were consistently high while both chromium and cobalt were not detected. Anatomical fractionation showed the shell to vary between 17.12 - 31.99%, carcass varied between 36.97 - 45.14% and the intestine varied between 18.80 - 22.74%. Snails interact with man in a variety of ways, the beneficial interactions are enumerated. PMID:8833175

82

An overview of renal replacement therapy and health care personnel deficiencies in sub-Saharan Africa  

Summary Chronic kidney disease (CKD) is a public health problem in sub-Saharan Africa (SSA) but there is limited data to guide programs or plan interventions. To help set priorities and understand the needs for renal replacement therapy a baseline assessment is required. World Health Organization (WHO) databases and Medline were searched to determine the number of physicians, nephrologists, and dialysis centers and patients in SSA. Data on renal transplant (RTx) programs were collected from the WHO Global Observatory on Donation & Transplantation database for deceased-donor and living-donor RTx. Of the 47 countries in SSA only 15 had recent data with most rates of physicians per 10-000 population under 2.0. Nigeria and South Africa had the greatest absolute numbers of physicians and nephro...

83

Prevalence of mange among West African Dwarf sheep and goats and associated haematological and biochemical parameters  

This study was carried out to assess the prevalence of mange in sheep and goats in five local government areas (LGAs) of Ogun State in South Western Nigeria. A total of 4,973 sheep and 7,902 goats of West African Dwarf breeds were sampled of which only 4 (0.08%) of sheep and 42 (0.53%) of goats were confirmed positive for mange infestation. In all the LGAs sampled, Odeda LGA had the highest concentration of sheep (39%) and goats (51%) while Abeokuta South had the least percentage of sheep (1%) and goats (1%). All the mange-infested cases in sheep were recorded in just one LGA (Ewekoro) which constituted 0.24% of the population within the location. For goats, three out of five LGAs namely: Obafemi Owode, Ewekoro and Abeokuta North had prevalence of 1.46%, 0.53% and 0.72% respectively. There...

84

Development and Deployment of Fixed Wireless Access in South West Nigeria: Performance and Evaluation  

Fixed Wireless Access (FWA) involves the use of wireless technology to replace copper to connect subscribers to the telephone network. It is a variant of wireless broadband which provides an alternative in the so-called 'last mile' connectivity between the subscriber and the fixed telecommunications network. FWA could either be narrowband or broadband and it is predominantly deployed using the Code Division Multiple Access (CDMA) technology. In assessing the extent of development and deployment of FWA, the perspective of the operators and users was elicited primarily through the use of questionnaires. Issues like setup cost, tax, Government incentive, availability of infrastructure and manpower applied to the operators while on the users' part factors like quality of service, signal strength as well as call rate were considered. The South western zone of Nigeria is regarded as one of the most urbanized regions in the south of Sahara, this is not out of place considering the fact that Lagos which is the nation...

85

Survey of trace element composition of commercial infant formulas in the Nigerian market  

Concentrations of zinc (Zn), copper (Cu), cadmium (Cd), lead (Pb), iron (Fe), nickel (Ni), chromium (Cr), vanadium (V) and cobalt (Co) were measured in 190 samples covering 19 different brands of popular baby foods in Nigeria to assess whether the intakes complied with the recommended desired levels for essential metals and permissible levels for toxic elements. The mean concentrations of Zn, Cu, Cd, Pb, Fe, Ni, Cr, V and Co in different types of infant foods were found to vary from 1.8-7.8; <0.001-0.1; <0.001-0.02; 0.01-0.1; 4.4-25.8; 0.03-0.06; 0.1-1.6; <0.001-0.1 to <0.001-0.1 µg g-1, respectively. The average concentrations of these metals were higher in soy-based formulas than milk-based infant foods. The estimated average daily intakes of metals through the c...

86

Acute toxicity studies of the leaf extract of Ficus exasperata on haematological parameters, body weight and body temperature  

Introduction The plant, Ficus exasperata is popularly used in Nigeria and in several parts of Africa for a variety of ailments. Aim of study This study was thus mapped out to investigate the toxicity profile of the aqueous leaf extract (AET) on haematological parameters, body weight and body temperature in mice. Methodology In the present study, AET was evaluated for acute toxicity over 24h and 14-day periods. The LD50 was assessed via oral and intraperitoneal administration. Results The LD50 was indeterminable via the oral route but was determined to be 0.54g/kg i.p. In the 24h and 14 days single dose study, oral administration of 2.5, 5, 10 and 20g/kg of AET produced neither mortality nor changes in behavior or any other physiological activity in mice. Body weights and body temperatures ...

87

Solid waste reforms and informal recycling in Enugu urban area, Nigeria  

The status of solid waste management in a city is often considered an index for assessing governance. In cities of the developing world, the informal sector plays an important role in the management of solid waste. This paper examines the position of the informal recycling sector in the planning and reform of solid waste management in the city of Enugu, Nigeria. The paper is based on direct field observations, key-informant interviews with important stakeholders in solid waste management in Enugu, and review of relevant legislation, policy documents and reports on solid waste management. The paper highlights recent efforts to visibly improve governance through reform of solid waste management in the urban area. Contribution of informal recyclers towards handling the city's solid waste prob...

88

Environmental pollution in the Gulf of Guinea--a regional approach.  

Environmental pollution in the Gulf of Guinea (GOG) coastal zone has caused eutrophication and oxygen depletion in the lagoon systems, particularly around the urban centres, resulting in decreased fish (reproduction) levels and waterborne diseases. A pollution sources assessment was undertaken by six countries in the region as a first step in defining a region-wide Environmental Management Plan. Results show that households produce 90% of solid waste. Industry, however, is responsible for substantial amounts of hazardous waste, specifically the Nigerian petroleum industry. The latter is also responsible for the spilling of large amounts of oil. BOD load from industrial effluents is slightly larger than domestic loads in the industrialised coastal zone. Wastewater treatment systems are either absent or inadequate. Apart from large-scale gas flaring in Nigeria, air pollution, in terms of COx, HC, NOx and SO2 emissions, is contributed mainly by traffic. Particulates, originate mainly from industries and domestic biomass burning. PMID:12222886

89

Solid waste generation and management practices as a determinant of health status of people in Ijebu-Ode local government, Ogun State, Nigeria  

This study assessed solid waste generation and management practices as a determinant of health status of people in Ijebu-Ode local government, Ogun State, Nigeria. A total of 993 subjects were drawn from the 11 wards with the use of random-sampling technique. A descriptive research survey method was adopted for the study; four hypotheses were formulated and tested at the 0.05 significant level. A self-structured and validated questionnaire was used for data collection, and a reliability coefficient of 0.72 was obtained for the instrument using Cronbach's ? coefficient. Data analysis involved the use of frequency counts and percentages for the demographic data while multiple regression and Analysis of Variance (ANOVA) were used to test the hypotheses. The results, among other things, ...

90

Contributions of Environmental Clubs toward Improved Environmental Programs in Selected Secondary Schools in Ibadan, Nigeria  

The descriptive cross-sectional study assessed contributions of Youth Environmental Scout (YES) clubs toward sustainable environmental programs in selected schools in Ibadan, southwest Nigeria. It involved administration of questionnaires, in-depth interviews and observation checklists and results were analyzed using SPSS 10 software package. Results indicated deplorable state of infrastructure particularly basic amenities like water, excreta disposal, and waste management. Noise pollution was mainly due to vehicular traffic (40, 40%). However, Environmental Awareness (EA) in the three schools studied increased dramatically since the establishment of YES clubs. Waste recycling was found to be significantly associated (p less than 0.001) with the level of environmental awareness. Therefore, having YES clubs in schools would increase awareness and good environmental practices which key elements of environmental education. (Contains 3 tables and 6 figures.)

91

Occupational insecticide exposure and perception of safety measures among cacao farmers in southwestern Nigeria.  

The authors assessed occupational exposure hazards among cacao farmers in Southwestern Nigeria. They administered structured questionnaires, supplemented with oral interviews, to 150 farmers to obtain information on insecticide use and perception of safety measures. The farmers used lindane, diazinon, endosulfan, and propoxur for cacao mirid control. Factors promoting exposure included eating and drinking during spraying operations, failure to use protective clothing, improper storage and disposal of insecticides. Varying proportions of the farmers experienced common symptoms associated with exposure hazards. Few presented for medical treatment with complaints of frequent fever, strained breathing, sleeplessness, loss of memory, etc., symptoms which are suggestive of chronic pesticide poisoning. The authors concluded that biological monitoring of the effects of insecticides on the health of the farmers is urgently needed together with awareness campaign and training on pesticide safety measures. PMID:19864221

92

Local poultry biosecurity risks to highly pathogenic avian influenza in Kaduna State, Nigeria.  

The study appraised local poultry biosecurity risks to highly pathogenic avian influenza by assessing farmers' knowledge, beliefs and poultry practices using a standard questionnaire. Farmers' knowledge on transmission and prevention was high but low on disease recognition. Radio was ineffective at informing Islamic educated farmers. Extensive knowledge on transmission and protection did not result in behavioural change as farmers engaged in risky practices of selling, eating or medicating infected poultry and not reporting poultry death. Islamic educated farmers do not believe highly pathogenic avian influenza is a serious and preventable disease. Women are more likely to self medicate when experiencing influenza-like illness. Audio-visual aids would improve avian influenza recognition while involvement of community leaders would enhance disease reporting. Outbreak of highly pathogenic avian influenza in local poultry in Nigeria would follow a similar pattern in Southeast Asia if the risk perception among farmers is not urgently articulated. PMID:22869337

93

Improvement of the hygienic quality of wet `fufu' produced in South West Nigeria  

To improve the hygienic quality condition of wet `fufu', an indigenous fermented cassava product produced in South-West Nigeria, the processing facilities were upgraded and GMP implemented before HACCP application in processing plants in Abeokuta. The effectiveness of the GMP and HACCP was assessed by monitoring the environment and `fufu' production. Air sampling and swabbing of equipment surfaces revealed a microbiota which was consistent with the fermented product. The results before application of GMP and HACCP showed the predominance of Staphylococcus aureus in the wet `fufu' samples ranging between 1.1x104cfu/g and 2.5x105cfu/g. Monitoring after application showed that the raw materials, products, processing parameters conformed to the critical limits within which the safety of the fo...

94

Can food calorie be an index for poverty in a rural economy? An extrapolation from farm households in Ogun State, Nigeria  

Abstract The study assessed poverty in rural areas of Ogun State, Nigeria through the food energy (calorie) intake approach. A sample of 60 households (comprising of 346 members) were selected using a multistage sampling technique and were interviewed with the aid of well-structured questionnaire. Data were analysed using nutrient estimation techniques, cost of calorie method and poverty index. The estimated food poverty line was 64.72 naira. The incidence, intensity and severity of poverty were consistently higher among female-headed households and households that lack access to credit facilities with values 0.290, 0.359, 0.160 and 0.313, 0.371, 0.160 for the poverty measures respectively. Incidence of poverty reduces with educational level and age of household heads, but the correspondin...

95

Acne vulgaris in Nigerian adolescents - prevalence, severity, beliefs, perceptions, and practices  

Abstract Background Community-based studies of acne vulgaris conducted in many parts of the world show that it is very common in adolescents but little is known from Africa. Methods In a cross-sectional study, 539 randomly selected students aged 11-19 years in a secondary school in Kaduna, Nigeria were administered a questionnaire to assess self-report of acne, its severity and impact; beliefs and perceptions of causes, and treatments used. 418 students were later examined to detect and grade acne severity. Results 274 (50.8%) were male while 265 (49.2%) were female. Mean age for respondents was 16 years. 320 students (59.4%) self-reported acne. Of 418 students examined, 379 had acne giving a prevalence of 90.7%. There was no significant gender difference in prevalence at all ages of adole...

96

Concurrent urinary and intestinal schistosomiasis and intestinal helminthic infections in schoolchildren in Ilobu, South-western Nigeria  

A cross-sectional study was conducted in a schistosome-endemic rural community in Southwestern Nigeria. We assessed prevalence and intensity of soil-transmitted nematodes and the co-occurrence with Schistosoma haematobium and Schistosoma mansoni. Urine and stool samples from 419 schoolchildren were examined, and a questionnaire was administered to obtain socio-demographic characteristics. In total, 78.3% (328/419) were infected with at least one helminth species, with a prevalence (mean egg-count) of 55.1% (3069.2) of Ascaris lumbricoides, 41.1% (127.5) of S. haematobium, 22.7% (98.6) of hookworms, 17.9% (161.3) of Trichuris trichiura, and 10.3% (12.9) of S. mansoni. Multiple infections were significantly more common among children from households with more playmates, absence of toilet fac...

97

Comparison of Event-Based Methods Using Optical Coherence Tomography and Automated Perimetry to Detect the Progression of Glaucoma in Patients with Open-Angle Glaucoma.  

Background/Aims: To compare event-based methods for estimating the incidence of glaucoma progression using optical coherence tomography (OCT) and automated perimetry and to assess agreement between structural and functional tests for detecting glaucoma progression. Methods: Functional progression of glaucoma was estimated by guided progression analysis (GPA) using a Humphrey field analyzer (HFA), and structural progression was assessed by OCT and defined as the decrease in retinal nerve fiber layer thickness based on test-retest variability data of previous reports on clock-hour and quadrant maps. The level of agreement between structural and functional progression was evaluated using kappa statistics. Results: Fifty eyes of 50 patients with open-angle glaucoma were enrolled in this retrospective study. The incidence of visual field progression estimated by GPA was 18%. The occurrence of structural progression assessed by OCT ranged from 18 to 68%. The more stringent OCT progression criterion using a quadrant map showed the best agreement with HFA GPA (? = 0.423) and detected perimetric progression with high specificity, while the less stringent OCT criterion considering any clock hour showed the lowest agreement with functional progression (? = 0.098). Conclusion: OCT progression criteria based on test-retest variability showed moderate agreement with perimetric progression, and more stringent criteria showed better agreement with functional progression than less stringent ones. PMID:22846640

98

Health Impact Assessment of Solid Waste Disposal Workers in Port Harocurt, Nigeria  

The various health risks associated with solid waste disposal workers in Port Harcourt, Rivers State of Nigeria, were investigated. The aim is to assess the extent of exposure in terms of inhalation of toxic substances and its inherent adverse health effects on them since the workers are not adequately protected while doing their jobs. About 10 mL of venous blood was collected from each of the 35 solid waste disposal workers aged 21-50 years and from each of the 15 control subjects of the same age bracket who are not exposed. A well structured questionnaire was also given to all the solid waste disposal workers to assess their health profile. Haematological parameters, liver function test (LFT) and toxic substance (Pb, Cu, Zn) concentration in the blood were carried out. There were slight decrease in the haematological parameters and liver function test (LFT) results, as compared with the control subjects. The values obtained are: Hb 13.43±1.14 g dL-1, HCT 37.13±3.22%, WBC6.35±1.86x109 L-1, platelet 236.15±104.33x109 L-1, neutrophil 42.60±11.11% and monocyte 3.05±2.41% for solid waste workers. While the values for control subjects are: Hb 14.69±0.4 g dL-1, HCT 41.77±2.74%, WBC 7.23±1.21x109 L-1, platelets 282.40±33.76x109 L-1, neutrophil 58.65±5.87% and monocyte 5.77±2.03%. The lymphocyte counts for waste disposal workers was significantly higher (50.42±11.30%) and (32.83±5.32%) for the control subjects. The AST values increased significantly for solid waste workers with a mean AST concentration of (11.19±2.36 µ L-1) and 8.97±4.07 µL-1 for the control subjects. And mean total bilirubin increased progressively as the number of years of exposure increased (19.00 μmol L-1). The peak value was for workers exposed for about 7 year. The result also showed that mean lead, copper and Zinc concentrations were high for the solid waste workers (Pb = 0.07±0.05 mg L-1, Cu =0.22±0.08 mg L-1 and Zn = 0.56±0.48 mg L-1) while that of control subjects were Pb = 0.02±0.01 mg L-1, Cu =0.11±0.04 mg L-1 and Zn = 0.30±0.04 mg L-1. Malaria parasitaemia was high amongst the solid waste disposal workers. Adequate Personal Protective Equipment (PPE) should be provided to avoid epidemic among the workers. It can be inferred that the lymphocytosis observed in this category of workers may indicate the presence of bacterial and protozoal infections, while a mild eosinophilia might be as a result of allergic disorders and helminthic infections.

99

Public Health European Commission  

Background In Sub Saharan Africa, the incidence of hypertension and other modifiable cardiovascular risk factors is growing rapidly. Poor adherence to prescribed prevention and treatment regimens by patients can compromise treatment outcomes. Patient-centered cardiovascular health education is likely to improve shortcomings in adherence. This paper describes a study that aims to develop a cardiovascular health education program for patients participating in a subsidized insurance plan in Nigeria and to evaluate the applicability and effectiveness in patients at increased risk for cardiovascular disease. Methods/Design Design: The study has two parts. Part 1 will develop a cardiovascular health education program, using qualitative interviews with stakeholders. Part 2 will evaluate the effectiveness of the program in patients, using a prospective (pre-post) observational design. Setting: A rural primary health center in Kwara State, Nigeria. Population: For part 1: 40 patients, 10 healthcare professionals, and 5 insurance managers. For part 2: 150 patients with uncontrolled hypertension or other cardiovascular risk factors after one year of treatment. Intervention: Part 2: patient-centered cardiovascular health education program. Measurements: Part 1: Semi-structured interviews to identify stakeholder perspectives. Part 2: Pre- and post-intervention assessments including patients' demographic and socioeconomic data, blood pressure, body mass index and self-reporting measures on medication adherence and perception of care. Feasibility of the intervention will be measured using process data. Outcomes: For program development (part 1): overview of healthcare professionals' perceptions on barriers and facilitators to care, protocol for patient education, and protocol implementation plan. For program evaluation (part 2): changes in patients' scores on adherence to medication and life style changes, blood pressure, and other physiological and self-reporting measures at six months past baseline. Analysis: Part 1: content analytic technique utilizing MAXQDA software. Part 2: univariate and multilevel analysis to assess outcomes of intervention. Discussion Diligent implementation of patient-centered education should enhance adherence to cardiovascular disease prevention and management programs in low income countries. Trial Registration ISRCTN47894401 PMID:16722567

100

Changes in the burden of malaria in sub-Saharan Africa  

Background Durable lining (DL) is a deltamethrin-impregnated polyethylene material, which is designed to cover domestic walls that would normally be sprayed with residual insecticide. The operational success of DL as a long-lasting insecticidal substrate will be dependent on a high level of user acceptability as households must maintain correctly installed linings on their walls for several years. Preliminary trials were undertaken to identify a material to develop into a marketable wall lining and to assess its level of acceptability among rural and urban populations. Methods In Angola (n=60), prototype DL and insecticide-treated plastic sheeting (ITPS) were installed on urban house walls and ceilings, respectively, and acceptability was compared to indoor residual spraying (IRS) (n=20) using a knowledge, attitude and practice (KAP) questionnaire. In Nigeria (n=178), three materials (prototype DL, ITPS and insecticide-treated wall netting) were distributed among rural and urban households. User opinions were gathered from focus group discussions, in-depth interviews and KAP questionnaires. Results In Angola, after two weeks, the majority of participants (98%) expressed satisfaction with the products and identified the killing of insects as the materials’ principal benefits (73%). After one year, despite a loss of almost 50% of households to refugee repatriation, all 32 remaining households still asserted that they had liked the DL/ITPS in their homes and given the choice of intervention preferred DL/ITPS to IRS (94%) or insecticide-treated nets (78%). In Nigeria, a dichotomy between rural and urban respondents emerged. Rural participants favoured wall adornments and accepted wall linings because of their perceived decorative value and entomological efficacy. By contrast, urban households preferred minimal wall decoration and rejected the materials based upon objections to their aesthetics and installation feasibility. Conclusions The high level of acceptability among rural inhabitants in Nigeria identifies these communities as the ideal target consumer group for durable wall linings. The poorer compliance among urban participants suggests that wall linings would not be readily adopted or sustained in these regions. If DL is as well received by other rural populations it could overcome some of the logistical constraints associated with spray campaigns and has the potential to become a long-lasting alternative to IRS in malaria endemic areas. PMID:20637696

 
 
 
 
101

Toxoplasma gondii: from animals to humans  

Introduction Most HIV/AIDS infections in women occur at a younger age, during the first few years after sexual debut. This study was therefore designed to assess factors associated with the knowledge and utilization of the prevention of mother-to-child transmission (PMTCT) services by the teenage pregnant women when compared to mature pregnant women in Ogun state, Nigeria. Methods This study is an analytical cross-sectional study. A total sample of all pregnant women [52 teenagers and 148 adults] attending the primary health care centres in Sagamu local government area, Ogun State, Nigeria within a 2?months period were recruited into the study. Results A total of 225 respondents were recruited into the study. The overall point prevalence of HIV/AIDS infection among those that had been tested and disclosed their result was 4 [2.8%]. The prevalence of HIV among the teenagers was 2 [7.4%] compared with 2 [1.8%] among older women. Only 85 [37.8%] of all respondents were tested through the Voluntary counseling and testing (VCCT) programme and 53 (23.7%) were aware of antiretroviral therapy while 35 (15.6%) have ever used the PMTCT services before. There was no statistically significant difference in the knowledge of the teenage pregnant women when compared with the older women about mother to child transmission (MTCT) [OR?=?1.47, C.I?=?0.57-3.95] and its prevention [OR?=?0.83, C.I?=?0.38-1.84]. The teenagers were 3 times less likely to use the services when compared with the older women. [OR?=?0.34, C.I?=?0.10-1.00]. Those from the low socio-economic background were about 6 times more likely to utilize PMTCT facilities when compared to those from high socioeconomic background [OR?=?6.01, C.I?=?1.91-19.19]. Conclusion The study concludes that the teenage pregnant women who were more vulnerable to HIV/AIDS infection did not utilize PMTCT services as much as the older pregnant women. Special consideration should be given to teenagers and those from high socioeconomic group in the design of scale up programmes to improve the uptake of PMTCT services in Nigeria and other low income countries. PMID:11113252

102

Environment, safety and health progress assessment of the Fernald Environmental Management Project (FEMP)  

This report documents the results of the Environment, Safety, and Health (ES&H) Progress Assessment of the Fernald Environmental Management Project (FEMP), Fernald, Ohio, conducted from October 15 through October 25, 1991. The Secretary of Energy directed that small, focused, ES&H Progress Assessments be performed as part of the continuing effort to institutionalize line management accountability and the self-assessment process in the areas of ES&H. The FEMP assessment is the pilot assessment for this new program. The objectives for the FEMP ES&H Progress Assessment were to assess: (1) how the FEMP has progressed since the 1989 Tiger Assessment; (2) how effectively the FEMP has corrected specific deficiencies and associated root causes identified by that team; and (3) whether the current organization, resources, and systems are sufficient to proactively manage ES&H issues.

103

Background Information Framework for the National Assessment of Educational Progress.  

The National Assessment of Educational Progress (NAEP) has been established by law to monitor the academic achievement of American students. In addition to its academic assessments, NAEP has collected information from hundreds of non-cognitive or backgrou...

104

Epidemiology of poliomyelitis--options and update.  

Poliomyelitis is a disease of major public health importance. Since the launch of the Global Poliomyelitis Eradication Initiative in 1988, considerable progress has been achieved globally. At present, the causative agent for the disease--poliovirus--remains endemic in only four countries (Afghanistan, India, Nigeria and Pakistan). The poliovirus eradication plan, as outlined in the WHO strategic plan for 2004--2008, incorporates priority activities for each phase of the plan: (i) polio eradication certification for regions, (ii) oral poliovirus vaccine (OPV) cessation phase, and (iii) post-OPV phase. The ultimate goal to eventually stop all vaccination is, however, jeopardized by the emergence of vaccine-derived polioviruses and the risk of bioterrorism. In the post-eradication era, individual countries will be presented with guidelines on OPV cessation and inactivated poliovirus vaccine (IPV) usage. This paper, presented during the Asian Pacific Pediatric Association (APPA) meeting in Pattaya, Thailand from 20 to 22 July 2006, provides an update on the current global situation, focusing on the progress and challenges faced by different countries in their quest for poliovirus eradication. PMID:18755232

105

Cardiovascular risk management and its impact on hypertension control in primary care in low-resource settings: a cluster-randomized trial/ Prise en charge du risque cardiovasculaire et impact sur le contrôle de l'hypertension par les soins de santé primaires dans les pays disposant de faibles ressources: essai en grappes randomisé/ La gestión del riesgo cardiovascular y su impacto en el control de la hipertensión arterial en la atención primaria en los entornos con recursos escasos: ensayo aleatorizado por conglomerados  

Abstract in spanish OBJETIVO: Evaluar un paquete sencillo de gestión del riesgo cardiovascular para evaluar y gestionar ese riesgo usando la hipertensión como punto de acceso en los centros de atención primaria en los entornos con pocos recursos. MÉTODOS: Se seleccionaron dos regiones geográficamente distantes de dos países (China y Nigeria), para proceder luego a elegir al azar y emparejar diez pares de centros de atención primaria de cada región. Las regiones fueron asignadas aleat (more) oriamente a un grupo de control, que recibió la atención habitual, o a un grupo de intervención, al que se aplicó el paquete de gestión del riesgo cardiovascular. En cada establecimiento se estudió a 60 pacientes consecutivos con hipertensión arterial. En los centros de intervención se informó a los pacientes acerca de los factores de riesgo al comienzo del estudio y se instauró tratamiento con hidroclorotiazida a los 4 meses en los pacientes con riesgo medio de evento cardiovascular, de acuerdo con un algoritmo de tratamiento normalizado. El criterio de valoración principal fue la variación de la tensión arterial sistólica respecto al nivel basal al cabo de 12 meses. RESULTADOS: El estudio abarcó a 2397 pacientes con hipertensión basal: 1191 en 20 centros de intervención y 1206 en 20 centros de control. La tensión arterial, sistólica y diastólica, disminuyó más en los pacientes del grupo de intervención que en los de control. Sin embargo, transcurridos 12 meses, más de la mitad de los pacientes seguían con la hipertensión no controlada (tensión arterial sistólica > 140 mmHg, o diastólica > 90 mmHg). Los factores de riesgo asociados al comportamiento habían mejorado entre los pacientes del grupo de intervención en Nigeria, pero no en China. Solo un 2% de los pacientes hipertensos tuvieron que ser derivados al siguiente nivel asistencial. CONCLUSIÓN: Incluso en los entornos con recursos escasos, es posible evaluar y tratar eficazmente a los pacientes hipertensos en los centros de atención primaria. Abstract in english OBJECTIVE: To evaluate a simple cardiovascular risk management package for assessing and managing cardiovascular risk using hypertension as an entry point in primary care facilities in low-resource settings. METHODS: Two geographically distant regions in two countries (China and Nigeria) were selected and 10 pairs of primary care facilities in each region were randomly selected and matched. Regions were then randomly assigned to a control group, which received usual care, (more) or to an intervention group, which applied the cardiovascular risk management package. Each facility enrolled 60 consecutive patients with hypertension. Intervention sites educated patients about risk factors at baseline and initiated treatment with hydrochlorothiazide at 4 months in patients at medium risk of a cardiovascular event, according to a standardized treatment algorithm. Systolic blood pressure change from baseline to 12 months was the primary outcome measure. FINDINGS: The study included 2397 patients with baseline hypertension: 1191 in 20 intervention facilities and 1206 in 20 control facilities. Systolic and diastolic blood pressure decreased more in intervention patients than in controls. However, at 12 months more than half of patients still had uncontrolled hypertension (systolic blood pressure > 140 mmHg and/or diastolic blood pressure > 90 mmHg). Behavioural risk factors had improved among intervention patients in Nigeria but not in China. Only about 2% of hypertensive patients required referral to the next level of care. CONCLUSION: Even in low-resource settings, hypertensive patients can be effectively assessed and managed in primary care facilities.

106

Current molecular epidemiology of Lassa virus in Nigeria.  

Recent Lassa virus strains from Nigeria were completely or partially sequenced. Phylogenetic analysis revealed the predominance of lineage II and III strains, the existence of a previously undescribed (sub)lineage in Nigeria, and the directional spread of virus in the southern part of the country. The Bayesian analysis also provided estimates for divergence times within the Lassa virus clade. PMID:21191050

107

Assessment of the Vitamin B12 Status of Pregnant Women in Nigeria Using Plasma Holotranscobalamin  

Maternal vitamin B12 deficiency during pregnancy is an independent risk factor for neural tube defects and other neurological problems in infants. We determined the vitamin B12 status of 143 pregnant women in Nigeria representing all trimesters who presented to an antenatal clinic in Jos, Nigeria, u...

108

Polycyclic aromatic hydrocarbon burden in ambient air in selected Niger Delta communities in Nigeria.  

The Niger Delta area in Nigeria has major oil producing and refining centers that characterized enormous industrial activities, especially in the petroleum sector. These industrial processes release different kinds of atmospheric pollutants, of which there is paucity of information on their levels and health implications. The objective of this study was to determine the ambient levels of polycyclic aromatic hydrocarbons (PAHs) in communities of a local government area (Eleme) where oil wells, petrochemical installations, a refinery, and a fertilizer complex are located. Respirable particulate matter (PM) in air were collected using Anderson high-volume sampler with PM with aerodynamic diameter > 10 microm (PM10) inlet for collecting filterable, particle-bound PAHs according to standard methods. PAHs were analyzed following standard methods for the 16 World Health Organization (WHO) prioritized components. The results were compared against the levels in another local government area (Ahoada East) with low industrial presence. The average total PAH concentration in Eleme of 9.2 microg/m3 was among the highest in the world; by contrast, the average concentration in Ahoada East was only 0.17 ng/m3. The most prominent PAHs at Eleme were those known to be carcinogenic and included benzo(a)pyrene (1.6 x 10(4) ng/m3 at bubu), benzo(k)fluoranthene (2.4 x 10(4) ng/m3 at Akpajo where a petrochemical is located), pyrene (3.1 x 10(3) ng/m3 at Ogale), and indeno(1,2,3-cd)pyrene (9.1 x 10(3) ng/m3 at Akpajo). Data from this study emphasize the need for a comprehensive source apportionment study and an assessment of the health effects of oil production on local communities of Nigeria where no such information currently exists. PMID:22393806

109

The spatial genetic differentiation of the legume pod borer, Maruca vitrata F. (Lepidoptera: Crambidae) populations in West Africa.  

The legume pod borer, Maruca vitrata, is an endemic insect pest that causes significant yield loss to the cowpea crop in West Africa. The application of population genetic tools is important in the management of insect pests but such data on M. vitrata is lacking. We applied a set of six microsatellite markers to assess the population structure of M. vitrata collected at five sites from Burkina Faso, Niger and Nigeria. Observed polymorphisms ranged from one (marker 3393) to eight (marker 32008) alleles per locus. Observed and expected heterozygosities ranged from 0.0 to 0.8 and 0.0 to 0.6, respectively. Three of the loci in samples from Nigeria and Burkina Faso deviated significantly from Hardy-Weinberg Equilibrium (HWE), whereas no loci deviated significantly in samples from Niger. Analysis of molecular variance (AMOVA) indicated that 67.3% level of the genetic variation was within individuals compared to 17.3% among populations. A global estimate of FST=0.1 (ENA corrected FST=0.1) was significant (P?0.05) and corroborated by pairwise FST values that were significant among all possible comparisons. A significant correlation was predicted between genetic divergence and geographic distance between subpopulations (R2=0.6, P=0.04), and cluster analysis by the program STRUCTURE predicted that co-ancestry of genotypes were indicative of three distinct populations. The spatial genetic variance among M. vitrata in West Africa may be due to limited gene flow, south-north seasonal movement pattern or other reproductive barriers. This information is important for the cultural, chemical and biological control strategies for managing M. vitrata. PMID:22717014

110

Possible biochemical markers of antiretroviral therapy (ART) failure in resource-constrained areas.  

Possible biochemical parameters that can distinguish clinically-failing people living with HIV/AIDS (PLWHA) from clinically-stable PLWHA on antiretroviral therapy (ART) were investigated in a north central location of Nigeria. The major aim of the study was to determine possible diagnostic biochemical markers that can be helpful in resource- and manpower-poor environments. Eighty (80) consenting persons living with HIV/AIDS who were on combined ART while attending a tertiary hospital in the North Central part of Nigeria were recruited for the study. Fifty (50) persons had clinically failing (CF) conditions while 32 were clinically stable (CS). Of the 50 CF cases 32 persons switched drugs while 18 did not in the course of their ART. In all, serum total bilirubin, total protein, total cholesterol, albumin, alkaline phosphatase (ALP), glucose, creatinine, urea and CD4 cell count were assayed. The values of these parameters in the CF and CS persons were statistically compared. The same parameters in the CF cases that switched drugs and those that maintained their drugs were also statistically compared with the corresponding values for the same parameters in the clinically stable persons. Alkaline phosphatase activity and total cholesterol levels and CD4 count in the CF cases were significantly (pd"0.05) different from the values for the CS persons. Only creatinine levels in CF persons that switched drugs differed significantly (pd"0.05) from the corresponding values in CF, persons that did not switch drugs even when there was no difference in creatinine values between the latter and the CS persons. CD4 count and total cholesterol levels may serve as useful indicators of potential clinically-failing and/or clinically stable cases of PLWHA on antiretroviral therapy. Creatinine levels on the other hand, may be useful in distinguishing PLWHA that switched drugs and those that did not. These parameters may serve as reliable rapid assessment tools for HIV/AIDS research and diagnosis in resources-poor areas. PMID:22416656

111

Prevalence of Equine Diseases in the Northern Guinea Savannah of Zaria, Nigeria  

There is no documentation on the diseases of horses in Zaria, Nigeria. A study was therefore conducted at the Ahmadu Bello University Veterinary Teaching Hospital (ABUVTH), Zaria, Nigeria to properly document the diseases of horses in the Northern Guinea Savannah of Zaria, Nigeria. The most common disease encountered was helminthosis, accounting for 809 (82.3%) of all the diseases diagnosed. Tetanus and rabies, which were also diagnosed in horses in this study have long been recognised as major zoonoses. The public health significance of these diseases in Zaria, Nigeria is discussed. It is concluded that research should be conducted to develop parasite vaccines from parasite strains native to Zaria, Nigeria to ameliorate parasitic diseases of horses in this area.   

112

The MacArthur Foundation in Nigeria: Report on Activities  

In 2007, Nigeria passed an important milestone: one elected government passed power to another for the first time in the nation's history. Though imperfect, the poll demonstrated powerfully that Nigeria's representative democracy was not a transient phase between periods of military repression but a growing reality. For 20 years, the MacArthur Foundation has given grants in Nigeria, in the belief that Africa's most populous nation was going through a transition of significance for the whole of sub-Saharan Africa. MacArthur has invested $100 million and supported almost 500 individuals and organizations committed to the vision of a Nigeria that is free and fair, and offers opportunity to all its citizens. MacArthur's efforts concentrate in three areas: (1) Strengthening Nigeria's universities; (2) Reducing maternal mortality and improving sexual and reproductive health; and (3) Advancing respect for human rights and the rule of law. This report describes the Foundation's grantmaking and lists the organizations it supports.

113

From intervention to invitation: reshaping adolescent sexual health through story telling and games.  

The University of Chicago and the University of Ibadan in Nigeria have partnered to exchange innovative insights into the sexual and reproductive health of disadvantaged populations in Chicago and Nigeria. Youth in both Chicago and Nigeria face disproportionately high rates of mortality and morbidity due to poor sexual and reproductive health. Traditional models have fallen short of the needs of these youth, so the University of Chicago is seeking to reframe and retool adolescent sexual health education. Game Changer Chicago is an initiative that incorporates digital storytelling, new media, and game design to conduct workshops with youth around issues of sexuality and emotional health. Based on the success of storytelling and digital media programs in Nigeria and the success of Game Changer Chicago, we believe this model holds promise for implementation in Nigeria and other sub-Saharan countries PMID:22916551

114

Imaging measures predict progression in progressive supranuclear palsy.  

OBJECTIVE: The aim of this work was to determine whether the progressive supranuclear palsy rating scale, a measure of disease severity, is associated with neuroanatomical changes in progressive supranuclear palsy. METHODS: We recruited 22 subjects with probable progressive supranuclear palsy who completed the progressive supranuclear palsy rating scale at 2 time points. All subjects had magnetic resonance imaging and diffusion tensor imaging. Associations were assessed between whole brain volume, ventricular volume, midbrain area and superior cerebellar peduncle fractional anisotropy, and baseline/change of the progressive supranuclear palsy rating scale. RESULTS: Superior cerebellar peduncle fractional anisotropy correlated with the total score and gait/midline subscore of the progressive supranuclear palsy rating scale. Whole brain volume, midbrain area, and disease duration predicted subsequent change over time in the gait/midline subscore of the progressive supranuclear palsy rating scale. CONCLUSIONS: Imaging measures could be useful to help predict clinical progression in subjects with progressive supranuclear palsy. © 2012 Movement Disorder Society. PMID:22415715

115

Incidence and cost estimate of treating pediatric adverse drug reactions in Lagos, Nigeria/ Incidência e estimativa de custo do tratamento de reações adversas a drogas de uso pediátrico em Lagos, Nigéria  

Abstract in portuguese CONTEXTO E OBJETIVOS: Reações adversas a drogas (RAD) podem causar hospitalização prolongada com alto custo de tratamento. Este efeito das RAD em crianças nunca foi avaliado na Nigéria. A incidência de RAD em pediatria e o custo estimado de tratamento em um período de 18 meses foram determinadas neste estudo. DESENHO E LOCAL: Estudo prospectivo observacional de crianças admitidas nas unidades pediátricas do Hospital Universitário do Estado de Lagos (LASUTH) na (more) Nigéria, entre julho de 2006 e dezembro de 2007. MÉTODOS: Cada paciente foi avaliado para RAD durante a admissão. Os custos médicos e não médicos para o hospital e para o paciente foram estimados para cada RAD pela revisão das contas médicas e da farmácia, pelos registros médicos, pelos exames necessários para diagnóstico e pelas entrevistas com os pais. Os custos foram estimados em nairas (moeda nigeriana) de 2007 a partir das perspectivas do hospital (governo), dos usuários de serviços (pacientes) e da sociedade (portadores dos custos totais atribuídos ao tratamento de RAD). A estimativa de custo total foi apresentada em dólares americanos (US) de 2007. RESULTADOS: Duas mil e quatro crianças foram admitidas durante este estudo; 12 (0,6%) foram admitidas devido a RAD e 23 (1.2%) desenvolveram RAD durante admissão. Quarenta RAD foram suspeitadas nesses 35 pacientes e envolveram 53 medicamentos. Antibióticos (50%) foram as drogas mais suspeitas. Aproximadamente 1.83 milhões de nairas (US 15,466.60) foram gastos para cuidar de todos os pacientes admitidos por RAD. CONCLUSÕES: O tratamento das RAD pediátricas foi bastante caro. As políticas de uso de drogas em pediatria na Nigéria devem ser revistas para desencorajar a auto-medicação, a prescrição de polifarmácia e a venda de medicamentos de prescrição sem prescrição. Abstract in english CONTEXT AND OBJECTIVES: Adverse drug reactions (ADRs) may cause prolonged hospital admissions with high treatment costs. The burden of ADRs in children has never been evaluated in Nigeria. The incidence of pediatric ADRs and the estimated cost of treatment over an 18-month period were determined in this study. DESIGN AND SETTING: Prospective observational study on children admitted to the pediatric wards of the Lagos State University Teaching Hospital (LASUTH) in Nigeria, (more) between July 2006 and December 2007. METHODS: Each patient was assessed for ADRs throughout admission. Medical and non-medical costs to the hospital and patient were estimated for each ADR by reviewing the medical and pharmacy bills, medical charts and diagnostic request forms and by interviewing the parents. Cost estimates were performed in 2007 naira (Nigeria currency) from the perspectives of the hospital (government), service users (patients) and society (bearers of the total costs attributable to treating ADRs). The total estimated cost was expressed in 2007 United States dollars (USD). RESULTS: Two thousand and four children were admitted during the study; 12 (0.6%) were admitted because of ADRs and 23 (1.2%) developed ADR(s) during admission. Forty ADRs were suspected in these 35 patients and involved 53 medicines. Antibiotics (50%) were the most suspected medicines. Approximately 1.83 million naira (USD 15,466.60) was expended to manage all the patients admitted due to ADRs. CONCLUSIONS: Treating pediatric ADRs was very expensive. Pediatric drug use policies in Nigeria need to be reviewed so as to discourage self-medication, polypharmacy prescription and sales of prescription medicines without prescription.

116

White Matter Lesion Progression in LADIS: Frequency, Clinical Effects, and Sample Size Calculations.  

BACKGROUND AND PURPOSE: White matter lesion (WML) progression has been advocated as a surrogate marker in intervention trials on cerebral small vessel disease. We assessed the rate of visually rated WML progression, studied correlations between lesion progression and cognition, and estimated sample sizes for clinical trials with pure WML progression vs combined WML progression-cognitive outcomes. METHODS: Those 394 participants of the Leukoaraiosis and Disability Study (LADIS) study with magnetic resonance imaging scanning at baseline and 3-year follow-up were analyzed. WML progression rating relied on the modified Rotterdam Progression Scale. The Vascular Dementia Assessment Scale global score and a composite score of specific executive function tests assessed longitudinal change in cognition. Sample size calculations were based on the assumption that treatment reduces WML progression by 1 grade on the Rotterdam Progression Scale. RESULTS: WML progression related to deterioration in cognitive functioning. This relationship was less pronounced in subjects with early confluent and confluent lesions. Consequently, studies in which the outcome is cognitive change resulting from treatment effects on lesion progression will need between 1809 subjects per treatment arm when using executive tests and up to 18 853 subjects when using the Vascular Dementia Assessment Scale score. Studies having WML progression as the sole outcome will need only 58 or 70 individuals per treatment arm. CONCLUSIONS: WML progression is an interesting outcome for proof-of-concept studies in cerebral small vessel disease. If cognitive outcome measures are added to protocols, then sample size estimates increase substantially. Our data support the use of an executive test battery rather than the Vascular Dementia Assessment Scale as the primary cognitive outcome measure. PMID:22879094

117

Vegetation zones and their sections in northwestern Europe  

Background The use of natural bioactive compounds in conventional chemotherapy is a new direction in cancer treatment that is gaining more research attention recently. Bioactive polysaccharides and polysaccharide-protein complexes from some fungi (edible mushrooms) have been identified as sources of effective and non-toxic antineoplastic agents. Selected oyster mushrooms (Pleurotus pulmonarius and P. ostreatus being local [Nigeria] and exotic strains, respectively) were cultured on a novel medium of yeast extract supplemented with an ethanolic extract of Annona senegalensis, and the antileukemic potential of their metabolites was studied. Methods Leukemia was successfully induced in Wister rats by intravenous injection (0.2 mL) of a benzene solution every 2 days for 3 consecutive weeks. The aqueous solution of fungal metabolites (20 mg/mL) produced by submerged fermentation was orally administered (0.2 mL) before, during, and after leukemia induction. Leukemia burden was assessed by comparing the hematological parameters at baseline and after leukemia induction. The immunomodulatory potential of the metabolites was assessed by using a phagocytic assay (carbon clearance method). The ability to enhance leukopoiesis was assessed by using the total leukocyte count. Results Leukemia induction resulted in significant anemia indices and leukocytosis (P<0.05) in the experimental rats. Both metabolites equally enhanced leukopoiesis and demonstrated phagocytic actions; P. ostreatus activity was significantly higher than that of P. pulmonarius (P<0.05). Conclusion The metabolites exhibited profound antileukemic potential by suppressing leukemia and demonstrating immunotherapeutic activities on animals after oral administration in various experimental groups. PMID:18950428

118

Material flows of mobile phones and accessories in Nigeria: Environmental implications and sound end-of-life management options  

Presently, Nigeria is one of the fastest growing Telecom markets in the world. The country's teledensity increased from a mere 0.4 in 1999 to 10 in 2005 following the liberalization of the Telecom sector in 2001. More than 25 million new digital mobile lines have been connected by June 2006. Large quantities of mobile phones and accessories including secondhand and remanufactured products are being imported to meet the pent-up demand. This improvement in mobile telecom services resulted in the preference of mobile telecom services to fixed lines. Consequently, the contribution of fixed lines decreased from about 95% in year 2000 to less than 10% in March 2005. This phenomenal progress in information technology has resulted in the generation of large quantities of electronic waste (e-waste) in the country. Abandoned fixed line telephone sets estimated at 120,000 units are either disposed or stockpiled. Increasing quantities of waste mobile phones estimated at 8 million units by 2007, and accessories will be generated. With no material recovery facility for e-waste and/or appropriate solid waste management infrastructure in place, these waste materials end up in open dumps and unlined landfills. These practices create the potential for the release of toxic metals and halocarbons from batteries, printed wiring boards, liquid crystal display and plastic housing units. This paper presents an overview of the developments in the Nigerian Telecom sector, the material in-flow of mobile phones, and the implications of the management practices for wastes from the Telecom sector in the country.

119

Public budgeting, public policy, and the politics of resource allocation in Nigeria  

The problem of determining who gets what in terms of allocating the nation's resources has plagued Nigerian leaders since independence. It is in this context that this dissertation is focused on the politics of the federal governments's use of the budget as an effective mechanism for mobilizing and constructively utilizing the nation's human and material resources to improve the general well-being of all segments of the Nigerian society. This study was conducted through direct interviews and discussions with some federal government officials and some Nigerian scholars concerned about the problems of development in Nigeria. From the findings, it is concluded that the federal budget process has not functioned efficiently and effectively as a vehicle for moving the nation forward in the direction of sustained and balanced economic progress. Whereas the above situation can be attributed to some structural deficiencies in the budgetary process, it can also be argued that bribery and corruption, fraud and misuse of public funds by politicians and top government officials, be they civilians or military, have undermined all efforts at using the budget as an instrument for accomplishing development objectives.

120

Global routine vaccination coverage, 2010.  

The Expanded Program on Immunization was established by the World Health Organization (WHO) in 1974 to ensure universal access to routinely recommended childhood vaccines. Six vaccine-preventable diseases initially were targeted: tuberculosis, poliomyelitis, diphtheria, tetanus, pertussis, and measles. In 1974, fewer than 5% of the world's infants were fully immunized; by 2005, global coverage with the third dose of diphtheria-tetanus-pertussis (DTP) vaccine (DTP3) was 79%, but many children, especially those living in poorer countries, still were not being reached. That year, WHO and the United Nations Children's Fund (UNICEF) developed the Global Immunization Vision and Strategy (GIVS), with the aim of decreasing vaccine-preventable disease--related morbidity and mortality by improving national immunization programs. One goal of GIVS was for all countries to achieve 90% national DTP3 coverage by 2010. This report summarizes the status of vaccination coverage globally and regionally in 2010 and progress toward meeting the GIVS goal. In 2010, 130 (67%) countries had achieved 90% DTP3 coverage, and an estimated 85% of infants worldwide had received at least 3 doses of DTP vaccine. However, 19.3 million children were not fully vaccinated and remained at risk for diphtheria, tetanus, and pertussis and other vaccine-preventable causes of morbidity and mortality; approximately 50% of these children live in India, Nigeria, and the Democratic Republic of Congo. Despite the overall improvement in vaccination coverage during the past 37 years, routine vaccination programs need to be strengthened globally, especially in countries with the greatest numbers of unvaccinated children. PMID:22071590

 
 
 
 
121

Osteonecrosis of the jaws in patients treated with intravenous bisphosphonates (BRONJ): a concise update  

This case highlights the fact that bone involvement is the commonest clinical manifestation of Sickle Cell Disease (SCD) both in the acute settings such as painful vaso-occlusive crisis (VOC) and as a source of chronic, progressive debility such as avascular necrosis (AVN), chronic osteomyelitis and fixed flexion deformity of joints. Protracted multiple bone involvement i.e. bilateral femoral and left humeral chronic osteomyelitis, Left elbow, Left knee and right humeral septic arthritis together with avascular necrosis of both femoral and right humeral heads, coupled with urinary tract infection (UTI) and decubitus ulcer in a young adult SCD patient is an unusual occurrence. This morbidities resulted into an uninterrupted 29 weeks of hospitalization for the patient who had previously enjoyed fairly good health. Various micro-organisms were sequentially cultured at various times and sites; these include E coli and Klebsiella in urine and klebsiella spp in the aspirates of the affected knee joint, elbow joint and femoral osteomyelitis. A screen for HIV 1 and 2 were non-reactive. Multidisciplinary approach was applied to the patient who was finally discharged home on a wheelchair. This case reflects not only the high susceptibility of SCD patients to infection, but also the morbidity and the attendant complications. It also highlights the need to forestall VOC which often predisposes to osteomyelitis. There is a need to have a highly organized, well-equipped and highly subsidized Sickle Cell and rehabilitation center in Nigeria in order to improve the medical care for SCD patients. PMID:19251474

122

Multiple bone and joint diseases in a nigerian sickle cell anaemia: a case report.  

This case highlights the fact that bone involvement is the commonest clinical manifestation of Sickle Cell Disease (SCD) both in the acute settings such as painful vaso-occlusive crisis (VOC) and as a source of chronic, progressive debility such as avascular necrosis (AVN), chronic osteomyelitis and fixed flexion deformity of joints.Protracted multiple bone involvement i.e. bilateral femoral and left humeral chronic osteomyelitis, Left elbow, Left knee and right humeral septic arthritis together with avascular necrosis of both femoral and right humeral heads, coupled with urinary tract infection (UTI) and decubitus ulcer in a young adult SCD patient is an unusual occurrence. This morbidities resulted into an uninterrupted 29 weeks of hospitalization for the patient who had previously enjoyed fairly good health.Various micro-organisms were sequentially cultured at various times and sites; these include E coli and Klebsiella in urine and klebsiella spp in the aspirates of the affected knee joint, elbow joint and femoral osteomyelitis. A screen for HIV 1 and 2 were non-reactive.Multidisciplinary approach was applied to the patient who was finally discharged home on a wheelchair. This case reflects not only the high susceptibility of SCD patients to infection, but also the morbidity and the attendant complications. It also highlights the need to forestall VOC which often predisposes to osteomyelitis. There is a need to have a highly organized, well-equipped and highly subsidized Sickle Cell and rehabilitation center in Nigeria in order to improve the medical care for SCD patients. PMID:22708038

123

West Africa plans ambitious gas-to-power program  

For several years, Nigeria produced more natural gas than it could sell. The result was high levels of flaring. Recently, it has tried to reduce the amount flared, leaving it with potentially more gas to sell. A large, new, local market is now beginning to emerge in the form of gas-fired power stations across West Africa. Nigeria is planning a large number, as are many of its neighbours, and an export pipeline linking Nigeria with its western neighbours is already under construction. (Author)

124

Molecular identification of a new begomovirus associated with mosaic disease of Jatropha curcas L. in Nigeria.  

We report the complete nucleotide sequence of DNA-A of a begomovirus naturally infecting Jatropha curcas L. in Nigeria. Symptoms observed on infected plants were severe mosaic, mottling and blistering of leaves. The virus, which we provisionally name "jatropha mosaic Nigeria virus" (JMNV), has a monopartite genome of 2,779 to 2,789 nucleotides. Pairwise comparisons of DNA-A sequences showed that JMNV had maximum nucleotide sequence identity (72%) with a strain of tomato yellow leaf curl virus. Since there are widespread infections of jatropha in Nigeria showing similar symptoms as those investigated in the present study, JMNV may represent a significant threat to a promising bioenergy crop. PMID:23074041

125

Molecular Survey of Babesia canis in Dogs in Nigeria  

An epidemiological study of Babesia canis in dogs in Nigeria was performed. Four hundred blood samples collected from dogs in Nigeria were investigated using nested PCR and sequence analysis. On nested PCR screening, nine samples (2.3%) produced a band corresponding to a 698-bp fragment indicative of B. canis infection. Sequence analysis of the PCR products identified eight samples (2.0%) as B. canis rossi and the ninth (0.3%) as B. canis vogeli. This is the first report of the prevalence of B. canis rossi and B. canis vogeli in dogs in Nigeria.   

126

Basement geology in the sedimentary basins of Nigeria  

In Nigeria, the dominant type of basement rock intersected by wells drilled for hydrocarbons, limestone, or water is granite. The three sedimentary basins in Nigeria are underlain by continental crust except in the Niger delta, where the basement rock is interpreted to be oceanic crust. Most of the wells that penetrated the basement are in the Eastern Dahomey embayment of western Nigeria. A maximum thickness of about 12,000 m of sedimentary rocks is attained in the offshore western Niger delta, but maximum thicknesses of sedimentary rocks are about 2,000 m in the Chad basin and only 500 m in the Sokoto embayment.

127

Serologic Prevalence of Brucellosis in Horse Stables in Two Northern States of Nigeria  

Despite the endemicity of brucellosis in Nigeria, reports on equine brucellosis are rare. The Rose Bengal Plate Test (RBPT) was used to determine the serologic prevalence of Brucella abortus antibodies amongst 75 horses from three stables in two States of northern Nigeria. The highest prevalence (22.7%) was recorded in stable C located in Plateau State and the lowest (6.7%) was found in stable B in Kaduna State. The overall prevalence determined was 14.7%. There is need for the inclusion of horses in brucellosis surveillance and control strategies in Nigeria to safeguard people at high risk.   

128

INFORMED CONSENT PRACTICES IN NIGERIA  

ABSTRACT Most writing on informed consent in Africa highlights different cultural and social attributes that influence informed consent practices, especially in research settings. This review presents a composite picture of informed consent in Nigeria using empirical studies and legal and regulatory prescriptions, as well as clinical experience. It shows that Nigeria, like most other nations in Africa, is a mixture of sociocultural entities, and, notwithstanding the multitude of factors affecting it, informed consent is evolving along a purely Western model. Empirical studies show that 70-95% of Nigerian patients report giving consent for their surgical treatments. Regulatory prescriptions and adjudicated cases in Nigeria follow the Western model of informed consent. However, adversarial l...

129

Modeling the impacts of reforestation on future climate in West Africa  

This study investigates the potential impacts of reforestation in West Africa on the projected regional climate in the near two decades (2031-2050) under the SRES A1B scenario. A regional climate model (RegCM3) forced with a global circulation model (ECHAM5) simulations was used for the study. The study evaluates the capability of the regional model in simulating the present-day climate over West Africa, projects the future climate over the region and investigates impacts of seven hypothetical reforestation options on the projected future climate. Three of these reforestation options assume zonal reforestation over West Africa (i.e., over the Sahel, Savanna and Guinea), while the other four assume random reforestation over Nigeria. With the elevated GHGs (A1B scenario), a warmer and drier climate is projected over West Africa in 2031-2050. The maximum warming (+2.5°C) and drying (-2 mm day-1) occur in the western part of the Sahel because the West Africa Monsoon (WAM) flow is stronger and deflects the cool moist air more eastward, thereby lowering the warming and drying in the eastern part. In the simulations, reforestation reduces the projected warming and drying over the reforested zones but increases them outside the zones because it influences the northward progression of WAM in summer. It reduces the speed of the flow by weakening the temperature gradient that drives the flow and by increasing the surface drag on the flow over the reforested zone. Hence, in summer, the reforestation delays the onset of monsoon flow in transporting cool moist air over the area located downwind of the reforested zone, consequently enhancing the projected warming and drying over the area. The impact of reforesting Nigeria is not limited to the country; while it lowers the warming over part of the country (and over Togo), it increases the warming over Chad and Cameroon. This study, therefore, suggests that using reforestation to mitigate the projected future climate change in West Africa could have both positive and negative impacts on the regional climate, reducing temperature in some places and increasing it in others. Hence, reforestation in West Africa requires a mutual agreement among the West African nations because the impacts of reforestation do not recognize political boundaries.

130

A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats.  

ABSTRACT: BACKGROUND: The herbal preparation DAS-77, used for the treatment of various ailments in Nigeria, contains the milled bark of Mangifera indica L. and root of Carica papaya L. Toxicological assessment of the preparation was carried out in this study. METHODS: In the acute toxicity study, DAS-77 was administered to mice p.o.up to 10 g/kg and i.p. at 250-3000 mg/kg. Mortality within 24 h was recorded. In the chronic toxicity study, rats were treated p.o. for 90 days at doses of 80, 400 (therapeutic dose, TD) and 2000 mg/kg. By 90 days, animals were sacrificed and blood samples collected for hematological and biochemical analysis. Organs were harvested for weight determination, antioxidants and histopathological assessments. RESULTS: DAS-77 did not produce any lethality administered p.o. up to 10 g/kg but the i.p. LD50 was 1122.0 mg/kg. At TD, DAS-77 produced significant (p<0.05) reductions in body weight, food intake and K+, and increases in ovary weight, neutrophils and HDL, which were reversible. Histopathological presentations were generally normal. Effects at the other doses were comparable to those at TD except for reversible increases in antioxidants in the liver, kidney and testes, and sperm abnormality, and reductions in liver enzymes, sperm motility and count. CONCLUSIONS: Findings in this study revealed that DAS-77 is relatively safe with the potential for enhancing in vivo antioxidant activity. However, possibly reversible side-effects include electrolyte imbalance and sterility in males. PMID:22892317

131

Research Focus: Reflections on Science Education Research Presentations at ASE 2012  

The original call for research papers went out in the summer of 2011 and, by September, there were over thirty abstracts returned for review, from many countries including Hong Kong, Nigeria, Poland, Jamaica, Malta, the United States, Japan, Ireland and, of course, Britain. Of the proposals reviewed and accepted, 21 were finally presented at Liverpool over three days in January. Many of these 30-minute presentations proffered interesting findings, thoughtful interpretations and virtually all suggested ways to develop and improve science education. A key aim of the research series was to share useful and informative studies with practitioners and educators so they could engage more meaningfully in reflective discussion about what researchers do in science education, and why. The different approaches taken to research various aspects of science education ranged from small-scale pilot studies to extensive national investigations, illustrative and exploratory case studies, action research projects demonstrating effects of teaching, learning and assessment interventions and critical reviews of current policy and/or practice. The focus of the papers included: (1) the nature of training in primary and secondary science teaching; (2) the ways in which primary children can be supported to carry out research themselves; (3) current concerns regarding assessment policy and practices, types of practical work, alternate conceptions and ways of teaching to address them; (4) issues in teacher preparation; and (5) specific teaching topics such as magnetism and enquiry skills. This article highlights some of the events in the Science Education Research series of presentations at the 2012 ASE Annual Conference.

132

Solid waste management problems in secondary schools in Ibadan, Nigeria.  

Inappropriate solid waste management practices in schools in less-developed countries, particularly in major urban communities, constitute one of the major factors leading to declining environmental health conditions. The objective of the authors' descriptive, cross-sectional study was to assess solid waste management problems in selected urban schools in Ibadan, Nigeria. Eight secondary schools with average pupil populations not less than 500 per school were selected randomly. Four hundred questionnaires (50 per school) were administered. In addition, an observational checklist was used to assess the physical environment. Paper and plastics were the most frequently generated wastes. Common methods of solid waste disposal reported were use of dustbins for collection and open burning. Major problems perceived with current refuse disposal methods by the study students were odors, pest infestation, and spillages. Littering and spillages of solid waste were also common features reported. Data suggested inadequate waste management facilities and practices in study schools. The lack of refuse bins may have contributed to waste spillages and the burning practices. Odors may have arisen from both the decay of overstored organic waste rich in moisture and emissions from refuse burning. This scenario poses a community environmental health nuisance and may compromise school environmental quality. PMID:21949981

133

Healthcare waste management status in Lagos State, Nigeria: a case study from selected healthcare facilities in Ikorodu and Lagos metropolis.  

A survey of healthcare waste management practices and their implications for health and the environment was carried out. The study assessed waste management practices in 20 healthcare facilities ranging in capacity from 40 to 600 beds in Ikorodu and metropolitan Lagos, Lagos State, Nigeria. The prevailing healthcare waste management status was analysed. Management issues on quantities and proportion of different constituents of waste, segregation, collection, handling, transportation, treatment and disposal methods were assessed. The waste generation averaged 0.631 kg bed(-1) day(-1) over the survey area. The waste stream from the healthcare facilities consisted of general waste (59.0%), infectious waste (29.7%), sharps and pathological (8.9%), chemical (1.45%) and others (0.95%). Sharps/pathological waste includes disposable syringes. In general, the waste materials were collected in a mixed form, transported and disposed of along with municipal solid waste with attendant risks to health and safety. Most facilities lacked appropriate treatment systems for a variety of reasons that included inadequate funding and little or no priority for healthcare waste management as well as a lack of professionally competent waste managers among healthcare providers. Hazards associated with healthcare waste management and shortcomings in the existing system were identified. PMID:21746754

134

Impact of Three Years Training on Operations Capacities of Research Ethics Committees in Nigeria.  

This paper describes a three-year project designed to build the capacity of members of research ethics committes to perform their roles and responsibilities efficiently and effectively. The project participants were made up of a cross-section of the membership of 13 Research Ethics Committees (RECs) functioning in Nigeria. They received training to develop their capacity to evaluate research protocols, monitor trial implementation, provide constructive input to trial staff, and assess the trial's success in promoting community engagement in the research. Following the training, technical assistance was provided to participants on an ongoing basis and the project's impacts were assessed quantitatively and qualitatively. Results indicate that sustained investment in capacity building efforts (including training, ongoing technical assistance, and the provision of multiple tools) improved the participants' knowledge of both the ethical principles relevant to biomedical research and how effective REC should function. Such investment was also shown to have a positive impact on the knowledge levels of other RECs members (those who did not receive training) and the overall operations of the RECs to which the participants belonged. Building the capacity of REC members to fulfill their roles effectively requires sustained effort and investment and pays off by enabling RECs to fulfill their essential mission of ensuring that trials are conducted safely and ethically. PMID:22998425

135

Natural radioactivity in cultivated land in the vicinity of a phosphate fertilizer plant in Nigeria  

Natural radioactivity in soil and vegetable samples in cultivated land in the vicinity of an active phosphate fertilizer plant in Kaduna, Nigeria was carried out to assess the potential radiological impact of the plant on its immediate environment. The activity counting was carried out using sodium iodide gamma spectrometry. The annual committed effective dose for two vegetables in the farmlands due to uranium (^2^3^8U) and thorium (^2^3^2Th) was assessed. The mean activity concentration of radionuclides in the soil samples ranges from 20.5+/-7.3 to 31.6+/-4.1Bqkg^-^1 for ^2^2^6Ra, 19.6+/-1.6 to 53.2+/-3.7Bqkg^-^1 for ^2^3^2Th and 203.9+/-6.3 to 253.6+/-9.5Bqkg^-^1 for ^4^0K. The annual intake of ^2^3^8U and ^2^3^2Th from consumption of okra were 1.9Bqkg^-^1 and 5.22Bqkg^-^1 and for tomato...

136

Exploratory multivariate modeling and prediction of the physico-chemical properties of surface water and groundwater  

Physico-chemical properties of surface water and groundwater samples from some developing countries have been subjected to multivariate analyses by the non-parametric multi-criteria decision-making methods, PROMETHEE and GAIA. Complete ranking information necessary to select one source of water in preference to all others was obtained, and this enabled relationships between the physico-chemical properties and water quality to be assessed. Thus, the ranking of the quality of the water bodies was found to be strongly dependent on the total dissolved solid, phosphate, sulfate, ammonia nitrogen, calcium, iron, chloride, magnesium, zinc, nitrate and fluoride contents of the waters. However, potassium, manganese and zinc composition showed the least influence in differentiating the water bodies. To model and predict the water quality influencing parameters, partial least squares analyses were carried out on a matrix made up of the results of water quality assessment studies carried out in Nigeria, Papua New Guinea, Egypt, Thailand and India/Pakistan. The results showed that the total dissolved solid, calcium, sulfate, sodium and chloride contents can be used to predict a wide range of physico-chemical characteristics of water. The potential implications of these observations on the financial and opportunity costs associated with elaborate water quality monitoring are discussed.

137

Impact of climate change and adaptation strategies on crop production in Nigeria  

The vulnerability of agricultural to climate change is of particular interest to policy makers because the high social and economical importance of agriculture sector in Nigeria, which contributes approximately 40 percent to total GDP and support 70 percent of the population. It is necessary to investigate the potential climate change impacts in order to identify specific agricultural sectors and Agro-Ecological Zones that will be more vulnerable to changes in climatic conditions and implement and develop the most appropriate policies to cope with these changes. In this framework, this study aimed to assess the climate change impacts on Nigerian agricultural sector and to explore some of potential adaptation strategies for the most important crops in the food basket of the Country. The analysis was made using the DSSAT-CSM (Decision Support System for Agrotechnology Transfer - Cropping System Model) software, version 4.5. Crop simulation models included in DSSAT are tools that allows to simulate physiological process of crop growth, development and production, by combining genetic crop characteristics and environmental (soil and weather) conditions. In this analysis, for each selected crop, the models included into DSSAT-CSM software were ran, after a calibration phase, to evaluate climate change impacts on crop production. The climate data used for the analysis are derived by the Regional Circulation Model COSMO-CLM, from 1971 to 2065, at 8 km of spatial resolution. The RCM model output were "perturbed" with 10 Global Climate Models in order to have a wide variety of possible climate projections for impact analysis. Multiple combinations of soils and climate conditions, crop management and varieties were considered for each Agro-Ecological Zone of Nigeria. The climate impact assessment was made by comparing the yield obtained with the climate data for the present period and the yield obtainable under future changed climate conditions. The models ran by keeping fixed all the other input parameter (e.g., crop management, soils, etc..) and changing only the climate data. Direct and indirect effects of different CO2 concentrations projected for the future periods were separately explored to estimate the effect linked to it. Several adaptation strategies (e.g., introduction of full irrigation, shift of the ordinary sowing/planting date, changes in the ordinary fertilization management) were evaluated with the aim to reduce the negative impact of climate change on crop production. The results of the study, analyzed at state, AEZ and country level, will be discussed.

138

Progress toward poliomyelitis eradication - afghanistan and pakistan, january 2011-august 2012.  

In 1988, the World Health Assembly resolved to eradicate polio, which led to the establishment of the Global Polio Eradication Initiative (GPEI). In 2012, however, the transmission of indigenous wild poliovirus (WPV) continued uninterrupted in Afghanistan, Pakistan, and Nigeria, leading the World Health Assembly to declare completion of polio eradication a programmatic emergency for global public health. This report updates previous reports and describes polio eradication activities and progress in Afghanistan and Pakistan during January 2011-August 2012, as of September 9, 2012. During 2011, 80 WPV cases were confirmed in Afghanistan, compared with 25 WPV cases in 2010; 17 WPV cases were confirmed during January-August 2012, compared with 34 WPV cases for the same period in 2011. In Pakistan, 198 WPV cases were confirmed in 2011, compared with 144 WPV cases in 2010; 30 WPV cases were confirmed during January-August 2012, compared with 88 WPV cases during the same period in 2011. During January 2011-August 2012, no WPV type 3 (WPV3) cases were confirmed in Afghanistan, and four confirmed WPV3 cases and one case with coinfection of WPV3 and WPV type 1 (WPV1) were reported in Pakistan. Violence targeting vaccinators has occurred previously in Afghanistan and recently in Pakistan. To progress further toward interruption of WPV transmission within their countries and across their shared border, the governments of Afghanistan and Pakistan might consider reviewing the implementation of their national emergency action plans and determine how to enhance the safety of vaccination teams within conflict-affected areas of both countries. PMID:23034587

139

An automated carotid pulse assessment approach using Doppler ultrasound  

During cardiac arrest emergencies, lay rescuers are required to manually check the patient's carotid pulse after the delivery of defibrillation shocks to assess the cardiac resuscitation progress of the patient. As a more automated way of monitoring the resuscitation progress, a new Doppler-ultrasou...

140

The Effects of Bone Remodeling Inhibition by Alendronate on Three-Dimensional Microarchitecture of Subchondral Bone Tissues in Guinea Pig Primary Osteoarthrosis : Ming Ding, Carl Christian Danielsen and Ivan Hvid  

We assessed whether increase of subchondral bone density enhances cartilage stress during impact loading, leading to progressive cartilage degeneration and accelerated osteoarthrosis (OA) progression. Sixty-six male guinea pigs were randomly divided into six groups. During a 9-week treatment period,...

 
 
 
 
141

Progressive dyslexia: Evidence from Hungarian and English  

We report a patient with non-fluent Primary Progressive Aphasia who was premorbidly literate in two alphabetic scripts, Hungarian (L1) and English (L2). Testing was performed over a two-year period to assess the impact of progressive illness on oral reading and repetition of single words. Results sh...

142

Clinical correlation of brain MRI and MRS abnormalities in patients with Wilson disease  

Background: The progression of Wilson disease (WD), a disorder of copper metabolism, can be arrested by chelation therapy. However, neurologic deficits may persist despite adequate treatment. MRI is used to assess patients with WD, but previous attempts to correlate clinical progression with the inv...

143

Untitled  

Nov 5, 2009 ... Install Unity intermodule ventilation modification .... did medical missions in Venezuela and Nigeria. ... necessary to be acquired by the Tracking ...... virulence factors of S. pneumonia. ..... For fact sheets, imagery and more on ...

144

STS-129 Press Kit  

Nov 5, 2009 ... Install Unity intermodule ventilation modification .... did medical missions in Venezuela and Nigeria. ... necessary to be acquired by the Tracking ...... virulence factors of S. pneumonia. ..... For fact sheets, imagery and more on ...

145

fiscal year 1961  

for national security as it is for national growth. through space capabilities is a ...... Zealand, Nigeria, Norway, Pakistan, Portugal, Sudan, Thailand, United Arab. Republic, United ...... different social-political climate. . . We can only welcome this ...

146

LUNAR UTILIZATION  

heavy industry in space involving material tonnages and energy expen ditures on the scale of terrestrial ...... UAE KUW IPSAUDI AABI ad. 600. NIGERIA. NEEDED ...... I just can't resist remarking that all of that waste that you had indicated there ...

147

76 FR 57757 - Endangered Species; Receipt of Applications for Permit  

...applicant requests a permit to import biological specimens of African dwarf crocodiles (Osteolaemus tetraspis tetraspis) and slender snouted crocodiles (Crocodylus cataphractus) collected from the wild in Cameroon and Nigeria for the...

148

Pages 319-360 from Wings-ch5  

Shuttle was also a product of the Cold War environment of the nation. ...... erosion , deposition, and chemical ...... on a delta rocket to provide new information about the effects of clouds and aerosols ... the borders of Chad, Niger, Nigeria, and ...

149

World review: Africa  

The article gives information on contracts announced (and to whom) in some parts of Africa in the petroleum, natural gas and petrochemicals industries. Countries specifically mentioned are Algeria, Angola, Nigeria, South Africa and Tunisia.

150

radio frequency utilization in the bands of principal interest for ...  

In Burundi, Ethiopia, Nigeria, Sierra Leone, Gambia, Portuguese Oversea. Spa ...... Federal Republic of Germany, the band 1540 to 1660 MHz is also allocated to the fixed ... application of satellite techniques should first consider the poss- ibility ...

151

Science and stewardship to protect and sustain wilderness values ...  

Jun 5, 2012 ... Title: Science and stewardship to protect and sustain wilderness values: Ninth ... of Agriculture, Forest Service, Rocky Mountain Research Station. ... the Netherlands, New Zealand, Nigeria, Philippines, Puerto Rico, Russia, ...

152

An evaluation of the training needs of Nigerian estate surveyors for corporate real estate management practice  

Purpose - This paper aims to examine the skill requirements for the practice of corporate real estate management (CREM) in Nigeria. Design/methodology/approach - Questionnaires were distributed to 270 practising estate firms in Lagos State, Nigeria, 145 final year students of Estate Management in Obafemi Awolowo University, Ile Ife, Nigeria as well as corporate real executive officers of the 24 recapitalised commercial banks, 21 insurance and five GSM communication companies in Nigeria. A total of 260 questionnaires (58 per cent) were returned and found useful for the study. The study adopted the descriptive method of percentages, mean and proportion method for analysis. Findings - The study found that in rank order, the skill requirements for CREM were financial performance skill, investm...

153

76 FR 63623 - Board of Scientific Counselors, National Center for Environmental Health/Agency for Toxic...  

...update on ATSDR Science Symposium; update on Camp LeJeune; update on Environmental Health Tracking; presentation on hydraulic fracking; global health updates: indoor air pollution and health and lead in Nigeria. Agenda items are subject to change as...

154

Total Solar Eclipse of 2006 March 29 - NASA Eclipse Web Site  

Continuing northeast, the shadow's axis enters Nigeria at 09:21 UT (Figure 8). ...... have preferred basins for development, one of which lies south- west of ...... Sokoto. Zaria. Lome. Sokodé. Alexandria. Marsa Matruh. Iráklion. Khaniá. Al- Bayda ...

155

World Cocoa Situation, March 1990.  

World cocoa bean production for the October-September 1989/90 marketing year is estimated at 2.39 million tons, slightly below the record 1988/89 harvest. Larger crops are anticipated for Brazil, Nigeria, Malaysia, and Indonesia, while declines are foreca...

156

Sexuality Education in Schools: The International Experience and Implications for Nigeria.  

Nigeria is in the early stages of carrying out its new national policy on sexuality and reproductive health education. Worldwide, school-based programs are an important element of efforts to improve the reproductive health of young people. This paper revi...

157

2001 report  

entific basis for economic investment and policy decisions. ...... the year, South Africa and Nigeria joined the Cospas-Sarsat program, bringing the total number ...... be used to detect and map leafy spurge, an invasive plant species in Theodore ...

158

Flooding in Nigeria : Natural Hazards  

Oct 13, 2012 ... South of Idah, the Niger River ballooned into a sprawling temporary lake. Flash floods are common in Nigeria in the rainy season (May to September), ... floods had affected several other countries in west and central Africa by ...

159

Flooding in Nigeria : Image of the Day  

Oct 16, 2012 ... South of Idah, the Niger River ballooned into a sprawling temporary lake. Flash floods are common in Nigeria in the rainy season (May to September), ... floods had affected several other countries in west and central Africa by ...

160

NASA Visible Earth: Flooding in Nigeria  

Oct 13, 2012 ... South of Idah, the Niger River ballooned into a sprawling temporary lake. Flash floods are common in Nigeria in the rainy season (May to September), ... floods had affected several other countries in west and central Africa by ...

 
 
 
 
161

Political and legal implications of developing and operating a ...  

Syria, Jordan, Egypt and Iraq; or one that fed the FRG, DDR, Poland, .... The United States with North and South Pmerica, Greenland and Hawaii. 10.2 0 13.8 nlz. U1 ...... Morocco, Nigeria, Pakistan, Poland, Romania, Sierra Leone, Sudan, ...

162

Petroleum developments in central and southern Africa in 1967  

This review includes 43 countries, i.e., all of Africa except Morocco, Tunisia, Algeria, Libya, UAR, and Sudan. Overall statistics for Central and Southern Africa were severely affected by the civil war in Nigeria, which broke out at midyear, nearly closing petroleum operations in that country. Total annual production for Central and Southern Africa decreased 12.7% to 146,535,030 bbl. The decrease was mainly the result of partial shutdown in Nigeria. Gabon recorded a 132% increase whereas production in Angola and Congo declined 14.6% and 19.4%, respectively. No other countries produced oil in 1967. Exploratory drilling reached a new high of 149 wells completed, of which 24.6% were successful. Twenty-six discoveries were made in Nigeria and important discoveries also were made in Angola, Cameroun, Gabon, and Mozambique. In Angola, Gabon, and Nigeria, 122 development wells were drilled with 74.6% success.

163

In-vitro antibacterial effects of extracts of Nigerian tooth-cleaning sticks on periodontopathic bacteria.  

Aqueous extracts from 8 plants used for tooth-cleaning in Nigeria were tested for their ability to inhibit the growth of five periodontopathic bacteria, Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Eikenella corrodens and Campylobacter rectus. Extracts of all the plants ...

164

NASA/TP-2004-212762: Section 2  

The eclipse path begins in the tropical climate of northeastern Brazil, south of the ... Over northern Nigeria, the winds flowing into the ITCZ originate over the Sahara ..... The depressions have preferred basins for development, one of which lies ...

165

Challenges of Operating Across Borders  

Nov 15, 2011 ... U.S. Army Installation Management Command – Europe Region ... Nigeria. Canada. Colombia. Sweden. Bolivia. Ukraine. Spain. France ... EU Electronic Waste Manifest requirements – implemented into Host Nation laws with ...

166

NASA - 03-05-2009  

Mar 5, 2009... of Wautersia bacteria), condensate water (0.0 L), waste/EMU dump and other ... Yuri also took care of the regular daily IMS (Inventory Management ... CEO photo targets uplinked for today were Lagos, Nigeria Aerosol (the ...

167

Key Issues and Challenges Facing NASA  

Feb 3, 2010 ... most serious management and performance challenges facing NASA. ... significance in relation to NASA's mission; its susceptibility to fraud, waste, and ..... investigative success against cyber-criminals from Nigeria, Portugal, ...

168

02-28-2009 - NASA  

Feb 28, 2009... includes removal of food waste products, cleaning of compartments with vacuum ... while tracking moves in the IMS (Inventory Management System). .... CEO photo targets uplinked for today were Lagos, Nigeria Aerosol ...

169

NASA Langley Research Center Technology Transfer, SBIR/STTR ...  

On-Board Computing and Data Management ... Waste Processing and Reclamation ... Data Acquisition and End-to-End-Management .... Nepal, Netherlands, Netherlands Antilles, New Zealand, Nicaragua, Niger, Nigeria, Niue , North Korea ...

170

Report from space  

management of the earth's resources and for the protection of the environment that forms ..... toward the south will be extended toward Nigeria in the heart of Africa. ... about environmentally harmful industrial wastes in water and atmos- phere ...

171

NASA - Education Weekly Activity Report (WAR)  

Oct 10, 2007... problem-solving, critical thinking, leadership, and resource management. .... West Virginia GLOBE Trainers will return to Nigeria for the third GLOBE .... Ripening of Fruits and Vegetables; Mold Growth; How Much Is Waste?

172

cont.  

Australia, Belgium, Canada, France, Italy, Nigeria, Saudi. Arabia, South Africa, and the United Kingdom, as well ... lar-orbiting Operational Environmental Satellite System ..... Over the ocean, in addition to rain rates, AMSR-E provides sea ...

173

Policy on Abortion in the Nigerian Society : Ethical considerations  

Abortion is clearly one of the most controversal and divisive contemporary moral problems. This thesis is an investigation upon significant number of important, fundemental ethical questions in relation to policy of abortion in Nigeria.

174

47 CFR 2.106 - Table of Frequency Allocations.  

...286EAdditional allocation: in Cape Verde, Indonesia, Nepal, Nigeria...limited to the operation of wind profiler radars in accordance...arrival.G129Federal wind profilers are authorized...following conditions: (1) wind profiler locations...

175

NELA: A Community Response to HIV/AIDS in Nigeria  

The greatest current threat to humanity, most especially in the developing countries of the world, is HIV/AIDS. The first case of HIV/AIDS in Nigeria was in 1986 in Lagos. Due to inaction and denial by the people, there was a rapid but subtle transmission of the virus within Nigeria's various populations and communities. Presently, the disease has been diagnosed in all the 774 local government areas in Nigeria. The trend suggests that there will be a continued increase in the seroprevalence rate of the disease. Going by the trend and the probable impact on the economy, healthcare system, and the polity of the nation, among others if the spread is left unchecked, there is a need for concerted efforts from all the stakeholders at government and NGO level to develop and implement programmes to help slow down the spread, and mitigate the impact of, the disease among Nigeria's large population. One of the leading NGOs in Nigeria is Network on Ethics, Law/Human Rights, HIV/AIDS Prevention, Support and Care (NELA). NELA has implemented a number of projects on HIV/AIDS/STI prevention, training, management, care and support in Nigeria. It has collaborated with many international donors through their Nigerian offices in the past. Currently, NELA collaborates with International HIV/AIDS Alliance (IHAA) in Brighton United Kingdom, to provide support--both financial and technical--to community-based organisations and civil organisations in Southwest Nigeria to carry out different activities on HIV/AIDS Prevention, Support and Care. This article highlights the processes involved in reaching out to other organisations and various target groups by NELA to be able to implement many projects in Nigeria. In doing this, the authors focus on two major areas--NGO support work and support and care for people living with HIV/AIDS. The article reports on a project being funded by the United States Agency for International Development (USAID), Nigeria, through the IHAA. The project deals with technical and financial support for NGOs in South Western Nigeria to mitigate the impact of HIV/AIDS through participatory and community approaches. The project started early in February 2002 with support for ten NGOs. This has now risen to 25 in the five states (Oyo, Osun, Ondo, Ogun and Ekiti) of South Western Nigeria.

176

The fitness and functionality of culturally evolved communication systems  

This paper assesses whether human communication systems undergo the same progressive adaptation seen in animal communication systems and concrete artefacts. Four experiments compared the fitness of ad hoc sign systems created under different conditions when participants play a graphical communicatio...

177

OTEC support services. Quarterly technical progress report No. 11, 15 November 1980-14 February 1981  

Technical engineering and management support services for the Ocean Thermal Energy Conversion Program are listed along with their objectives. Progress is reported on the following: technical assessments, OTEC system integration, environment and siting considerations, and transmission subsystem considerations. (MHR)

178

Organization of the R region in maize. Annual progress report  

This progress report is comprised of 5 summaries of manuscripts devoted to investigations of the behavior of transposable insertion sequences, unusual recombinational events, and alternative means of assessing genetic homology.

179

Water Resources ???  

Water Resource, the English-language translation of Vodnye Resursy, details progress in the assessment of water resources, integrated water-resource use, water quality, and environmental protection. The coverage spans many areas of research, including prediction of variations in contin...

180

76 FR 50462 - Applications for New Awards; Technical Assistance and Dissemination To Improve Services and...  

...student's lack of academic development in...scores, or other performance measures are...Learner's lack of academic progress in reading...assessment and intervention to maximize student...instruction and academic interventions. Retrieved...

 
 
 
 
181

Design and Evaluation of ExO: An Ontology for Exposure Science: Document Published in Nature Precedings: Pre-publication research and preliminary findings  

Significant progress has been made in collecting and improving access to genomic, toxicology, and health data. These information resources lack exposure data required to translate molecular insights, elucidate environmental contributions to diseases, assess human health risks at ...

182

Space Flight  

Representative titles under this category are Assessing Technology Transfer, Conference .... Bioenergetics of Space Suits for Lunar Exploration ..... American, European, Asian, and Australian scientists reporting on research progress in the ...

183

76 FR 35619 - Labeling and Effectiveness Testing; Sunscreen Drug Products for Over-the-Counter Human Use  

...date, there are no clinical studies demonstrating...on the development of melanoma, which is the deadliest...hypotheses by assessing past experiences. Generally, prospective...Although data from clinical studies addressing the...which can progress into melanomas (Ref. 22)....

184

Measurements of tissue polypeptide-specific antigen and prostate-specific antigen in prostate cancer patients under intermittent androgen suppression therapy.  

The present study evaluated serial serum measurements of tissue polypeptide-specific antigen (TPS) in comparison with prostate-specific antigen (PSA) for assessment of tumour progression in patients with advanced prostate cancer receiving intermittent androgen suppression therapy (IAS). Twenty-three...

185

Children's Bureau  

... progress on our centennial anniversary, April 9, 2012. Watch the Centennial Video News RSS Feed Upcoming Webinar ... Assessment Reviews Title IV-E Reviews Research, Data & Technology Reporting Systems State & Tribal Information Systems Statistics & Research ...

186

77 FR 69814 - Agency Information Collection Activities; Comment Request; National Assessment of Educational...  

...subject areas, such as mathematics, reading, writing, science, U.S. history, civics, geography, economics, technology and engineering literacy, and the arts. The National Assessment of Educational Progress Authorization Act...

187

Vaimupuudega koolieelikute (re)habilitatsioonivajaduse määratlemine S/P = PAC formulariga / Kristel Voll  

Artikli autor uuris, kas ja kuidas on võimalik Eestis rakendada PAC (Progress Assessment Chart) formularide spetsiaalselt raskema vaimupuudega astme jaoks loodud varinti S/P=PACd mõõduka, raske ja sügava vaimupuudega koolieelikute sotsiaalsete oskuste taseme määramiseks

188

NATIONAL AERONAUTICS AND SPACE ADMINISTRATION  

to assess NASA's research progress for compliance with the Government ...... knowledge; incorporates results into complex computational models that can be used to ...... volcanic inflation and inundation dynamics from lahars and floods.

189

Radiological progression of cerebral metastases after radiosurgery: assessment of perfusion MRI for differentiating between necrosis and recurrence  

To assess the capability of perfusion MRI to differentiate between necrosis and tumor recurrence in patients showing radiological progression of cerebral metastases treated with stereotactic radiosurgery (SRS). From 2004 to 2006 dynamic susceptibility-weighted contrast-enhanced perfusion MRI scans ...

190

Safeguards research at Lawrence Livermore Laboratory  

The LLL safeguards research program includes inspection methods, facility assessment methodologies, value-impact analysis, vulnerability analysis of accounting systems, compliance with regulations, process monitoring, etc. Each of those projects is described as are their goals and progress. (DLC)

191

How and when Does Complex Reasoning Occur? Empirically Driven Development of a Learning Progression Focused on Complex Reasoning about Biodiversity  

In order to compete in a global economy, students are going to need resources and curricula focusing on critical thinking and reasoning in science. Despite awareness for the need for complex reasoning, American students perform poorly relative to peers on international standardized tests measuring complex thinking in science. Research focusing on learning progressions is one effort to provide more coherent science curricular sequences and assessments that can be focused on complex thinking about focal science topics. This article describes an empirically driven, five-step process to develop a 3-year learning progression focusing on complex thinking about biodiversity. Our efforts resulted in empirical results and work products including: (1) a revised definition of learning progressions, (2) empirically driven, 3-year progressions for complex thinking about biodiversity, (3) an application of statistical approaches for the analysis of learning progression products, (4) Hierarchical Linear Modeling results demonstrating significant student achievement on complex thinking about biodiversity, and (5) Growth Model results demonstrating strengths and weaknesses of the first version of our curricular units. The empirical studies present information to inform both curriculum and assessment development. For curriculum development, the role of learning progressions as templates for the development of organized sequences of curricular units focused on complex science is discussed. For assessment development, learning progression-guided assessments provide a greater range and amount of information that can more reliably discriminate between students of differing abilities than a contrasting standardized assessment measure that was also focused on biodiversity content. (Contains 9 tables, 8 figures and 1 note.)

192

Environment; Environnement  

Elf Angola and Elf Petroleum Nigeria (subsidiary companies of TotalFinaElf) have adopted the solution of electro-chlorination of Socrematic, Sterelec, for their offshore sites of Girassol (Angola) and of Amenam Kpono (Nigeria); searchers are thinking to use the ocean deeps to store carbon dioxide at 800 m depth, the carbon dioxide will be dissolved into water and will not come up to the surface again until several hundred years, the only disadvantage: the acidification of water. (O.M.)

193

Some observations on ethnoveterinary medicine in northern Nigeria.  

The Fulani are herdsmen of Northern Nigeria. For generations they have been moving their cattle in an annual migration pattern in search of water. The tracks are chosen carefully, however: tsetse-fly-infected areas are avoided. In his ten years of experience in Nigeria's veterinary sector--part of this time as special officer in charge of eradicating rinderpest--the author saw numerous examples of indigenous knowledge and practices that will be useful for the future development of animal health and production. PMID:8372425

194

Oil for development 2009  

In this report present key achievements for each of the various cooperation countries. Oil for Development (OfD) assistance has been important for the ability of a country like Ghana to improve petroleum resource management on its most important oil and gas field, and to better safeguard that the petroleum activities are conducted in an environmentally sustainable way. Competence building on Increased Oil Recovery (IOR), and negotiation training have helped to increase both the resource extraction potential and the revenue generation potential of a more mature oil producing country like Iraq. Furthermore, OfD has contributed to improving the legislative frameworks in several of our cooperating countries, including Afghanistan, Cambodia and Madagascar, although it will take time before we can assess to what extent the laws have been implemented. OfD's strong focus on providing legal assistance reflects our belief that clear divisions of roles and firm legal mandates are prerequisites for good governance of the petroleum sector and for attracting serious investors. A lot of our capacity building took place through seminars and more tailored workshops with a national or regional scope. We believe that some of these events have significantly increased awareness as well as the level of debate among government institutions and civil society. The oil production accounting workshop in Nigeria and the NOC workshop in Timor-Leste are particularly valid examples. Timor-Leste also addressed other petroleum sector governance issues with a focus on including civil society and by the end of 2009 had nearly fulfilled all criteria for becoming Extractive Industries Transparency Initiative (EITI) compliant. It should be noted that OfD assistance only made a relatively small contribution to this process, which was very much nationally driven. Petroleum related environmental issues were addressed at different levels and from different angles. A thorough environmental needs assessment was conducted for the petroleum sector in Ghana, and will provide the basis for future capacity building in this area. In Uganda, the first part of the Albertine Graben sensitivity atlas will provide an important input for the planned strategic environmental assessment (SEA) related to the petroleum sector. In Vietnam, Petrovietnam conducted a baseline study which found that steering documentation and guidelines for health, safety and environment had to a large extent been developed, and that implementation of the steering documentation had been 30% completed by end 2009. The political situation in some of the cooperating countries has led to no or limited progress in the OfD programmes. In Madagascar, one of the core countries, cooperation was frozen in March 2009 and has not yet been resumed. In Mauritania cooperation was stopped in 2008 after the military coup, but was resumed in December 2009 after elections had been held. On the Palestinian Territory the programme continues, but no activities were carried out in 2009 due to the conflict with Israel. In 2009, OfD received a number of new requests for Norwegian assistance in petroleum sector management. There was not enough spare capacity within the programme to increase the number of bilateral cooperation countries, but we have done our best to meet the increased demand by stepping up our regional efforts, particularly in West Africa. We also continued to cooperate closely with the World Bank and the IMF, as well as with other multilateral institutions such as the Asian Development Bank and the UNDP. The assistance provided to government institutions was supplemented by support of local civil society organizations through Norwegian and international non-governmental organizations. In 2009, seven Norwegian organizations, in addition to the international organizations Revenue Watch Institute and Global Witness, were granted funds for this purpose. Thematically, OfD continued the three-pronged approach to sound petroleum sector governance: resource management, environmental management and revenue management. These three areas constitute a thematic whole, and governance principles such as sustainability, transparency and accountability are cross-cutting. To make our perspective more operational, we developed an indicator based check-list for governance of the petroleum sector. This list will be an important tool for OfD in planning new programmes and revising the existing ones. The overarching goal of all Norwegian development assistance is to reduce poverty. Through OfD, we aim to use Norway's specialist expertise to assist developing countries in managing their petroleum resources in a way that generates economic growth and promotes the welfare of the whole population in an environmentally sustainable way. The direct assistance of OfD covers, however, only a limited, albeit crucial, part of the results chain that ends with poverty reduction.

195

Can Information and Communications Technology Application Contribute to Poverty Reduction? Lessons from Nigeria  

There is a growing optimism among international organizations such as United Nations Development Programme (UNDP) that Information and Communication Technology (ICT) can transform developing countries such as Nigeria to developed ones in a relatively short time. Experiences from Asian and European countries such as India, Bangladesh, Malaysia, Thailand, Serbia and Ukraine tend to confirm this claim. However, there are very few of such studies on African sub-regional experience. This study attempts to provide evidences from African sub-region particularly Nigeria. Data collected from Central Bank of Nigeria (CBN) is used to find relationships between poverty reduction indicators and telecommunication in Nigeria. The study reveals that generally, telecommunication contributions to indicators of poverty reduction are not significant. The major reason that can be adduced for the minimal contribution of telecommunication lines to poverty reduction is their concentration in urban centre coupled with level of literacy and poor infrastructural facilities in the sub-region and indeed Nigeria. Similarly, the poor's are not properly linked to demand and supply chains information including produce and labour markets as well as services such as credits extension, inputs and research information. The pervasive and widespread "quiet corruption" in public institutions in Nigeria also reduces effects of telecommunication on poverty reduction. (Contains 2 tables.)

196

Environment, Safety and Health progress assessment of the Idaho National Engineering Laboratory (INEL)  

The ES&H Progress Assessments are part of the Department`s continuous improvement process throughout DOE and its contractor organizations. The purpose of the INEL ES&H Progress Assessment is to provide the Department with concise independent information on the following: (1) change in culture and attitude related to ES&H activities; (2) progress and effectiveness of the ES&H corrective actions resulting from previous Tiger Team Assessments; (3) adequacy and effectiveness of the ES&H self-assessment programs of the DOE line organizations and the site management and operating contractor; and (4) effectiveness of DOE and contractor management structures, resources, and systems to effectively address ES&H problems. It is not intended that this Progress Assessment be a comprehensive compliance assessments of ES&H activities. The points of reference for assessing programs at the INEL were, for the most part, the 1991 INEL Tiger Team Assessment, the INEL Corrective Action Plan, and recent appraisals and self-assessments of INEL. Horizontal and vertical reviews of the following programmatic areas were conducted: Management: Corrective action program; self-assessment; oversight; directives, policies, and procedures; human resources management; and planning, budgeting, and resource allocation. Environment: Air quality management, surface water management, groundwater protection, and environmental radiation. Safety and Health: Construction safety, worker safety and OSHA, maintenance, packaging and transportation, site/facility safety review, and industrial hygiene.

197

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study  

Summary Background More than half of patients with multiple sclerosis have progressive disease characterised by accumulating disability. The absence of treatments for progressive multiple sclerosis represents a major unmet clinical need. On the basis of evidence that mesenchymal stem cells have a beneficial effect in acute and chronic animal models of multiple sclerosis, we aimed to assess the safety and efficacy of these cells as a potential neuroprotective treatment for secondary progressive multiple sclerosis. Methods Patients with secondary progressive multiple sclerosis involving the visual pathways (expanded disability status score 55-65) were recruited from the East Anglia and north London regions of the UK. Participants received intravenous infusion of autologous bone-marrow-derive...

198

The need for a new outlook on labor monitoring.  

Fetal heart rate monitors, including the newer pulse-oximetry and STAN monitors, are designed to detect fetal distress that affects less than 1% of women in labor. Non-progressive labor is a much more common disorder than fetal distress, with approximately 50% of women in labor requiring oxytocin. Current technology assessing labor progress is subjective and inaccurate. There is a need for objective and accurate technology to measure labor progress and the effect it may have on managing labor and, specifically, non-progressive labor. PMID:16690509

199

Early results of integrated malaria control and implications for the management of fever in under-five children at a peripheral health facility: a case study of Chongwe rural health centre in Zambia  

Background Pharmaceutical drug promotion is a means of informing health professionals about new drugs. The approach is often times unethical and inappropriate and may promote irrational prescribing. Dearth of information on impact of pharmaceutical drug promotion on prescribing behaviour of doctors in developing African countries has necessitated this study. We therefore aimed to determine the sources of drug information for doctors working in a teaching hospital in Nigeria and to assess the self-reported impact of the sources on their prescribing behaviour. Methods A total of 163 doctors working at the University College Hospital (UCH), Ibadan in Nigeria were evaluated with a questionnaire for their demographics and sources of drug information. For doctors who relied on drug promotion, they were asked to self-report and self-rate their opinion on extent of interactions with pharmaceutical companies as well as how such interactions had impacted on their prescribing behaviour. Apart from the demographics, each question was evaluated with a typical five-level Likert item. Data analyses were with simple descriptive statistics. Results Of the 400 doctors working at UCH, only 40.8% participated in the study. Drug information was sourced from colleagues (161, 98.8%), reference books (158, 96.9%), pharmaceutical sales representatives-PSRs (152, 93.2%), promotion materials (151, 92.6%), scientific papers/journals/internet (149, 91.4%), and drug promotion forum/product launches (144, 88.3%). Each source was highly utilized but there was no wide variation in their pattern of use. According to the self-report of over a half of the respondents, PSRs was an accurate and reliable drug information resource; PSRs increased their awareness of the promoted drugs; and their prescribing behaviours were influenced by information from PSRs. Conclusion Respondents tend to rely on a broad range of drug information resources which include potentially inappropriate resources such as PSRs. Since this study was based on self-report, the influence of drug information resources reported by the respondents on their prescribing behaviour may have been underestimated. Measures should be taken to minimize interactions between PSRs and the respondents. PMID:19292919

200

A flowchart for managing sexually transmitted infections among Nigerian adolescent females/ Algorithme pour la prise en charge des infections sexuellement transmissibles chez des adolescentes au Nigéria/ Diagrama para el manejo de las infecciones de transmisión sexual en mujeres adolescentes de Nigeria  

Abstract in spanish OBJETIVO: Elaborar un diagrama adecuado para evaluar el riesgo de tricomoniasis, clamidiasis y gonorrea en una población de mujeres adolescentes, no todas las cuales habían tenido experiencias sexuales o mantenían en ese momento una relación. MÉTODOS: Los datos empleados para elaborar el diagrama se obtuvieron a partir de estudios microbiológicos transversales de muchachas de 14 a 19 años de Port Harcourt (Nigeria). En el diagrama se hace un cribado teniendo en cue (more) nta (i) la experiencia sexual; (ii) la actividad sexual reciente; (iii) la eventual positividad de la prueba de la esterasa leucocitaria (EL) en orina; y (iv), entre los casos EL-negativos, los antecedentes de flujo maloliente o pruriginoso. RESULTADOS: De todas las adolescentes sometidas a ese cribado, el 26,2% recibieron tratamiento contra una cervicitis o vaginitis, y las infecciones por clamidias, gonococos y tricomonas fueron diagnosticadas correctamente en el 37,5%, 66,7%, y 50% de los casos, respectivamente. CONCLUSIÓN: Tratándose de una población de adolescentes, el diagrama es preferible al algoritmo para flujo vaginal empleado en los protocolos de manejo sindrómico, pero adolece aún de imprecisión y ha de ser adaptado a las condiciones locales. Abstract in english OBJECTIVE: To devise a flowchart suitable for assessing risk of trichomoniasis, chlamydia and gonorrhoea in an adolescent population, not all of whom will be sexually experienced or currently in a relationship. METHODS: The data used to derive the flowchart were generated from cross-sectional microbiological surveys of girls aged 14-19 years in Port Harcourt, Nigeria. The flowchart screened on the basis of: (i) sexual experience; (ii) recent sexual activity; (iii) a posit (more) ive urine leukocyte esterase (LE) test; and (iv) among LE negatives, a history of malodorous/pruritic discharge. FINDINGS: Using this flowchart, we found that 26.2% of all adolescents screened would receive treatment for cervicitis and vaginitis. Chlamydial, gonococcal, and trichomonal infections were correctly diagnosed in 37.5%, 66.7%, and 50 % of the cases, respectively. CONCLUSION: Although the flowchart is more suitable for an adolescent population than the vaginal discharge algorithm used in syndromic management protocols, it still lacks precision and needs adapting to local settings.

 
 
 
 
201

Neuroimaging comparison of primary progressive apraxia of speech and progressive supranuclear palsy.  

BACKGROUND AND PURPOSE: Primary progressive apraxia of speech, a motor speech disorder of planning and programming, is a tauopathy that has overlapping histological features with progressive supranuclear palsy. We aimed to compare, for the first time, atrophy patterns, as well as white matter tract degeneration, between these two syndromes. METHODS: Sixteen primary progressive apraxia of speech subjects were age- and gender-matched to 16 progressive supranuclear palsy subjects and 20 controls. All subjects were prospectively recruited, underwent neurological and speech evaluations and 3.0-Tesla magnetic resonance imaging. Grey and white matter atrophy was assessed using voxel-based morphometry and atlas-based parcellation, and white matter tract degeneration was assessed using diffusion tensor imaging. RESULTS: All progressive supranuclear palsy subjects had typical oculomotor/gait impairments, but none had speech apraxia. Both syndromes showed grey matter loss in supplementary motor area, white matter loss in posterior frontal lobes and degeneration of the body of the corpus callosum. Whilst lateral grey matter loss was focal, involving superior premotor cortex, in primary progressive apraxia of speech, loss was less focal extending into prefrontal cortex in progressive supranuclear palsy. Caudate volume loss and tract degeneration of superior cerebellar peduncles were also observed in progressive supranuclear palsy. Interestingly, area of the midbrain was reduced in both syndromes compared to controls, although this was greater in progressive supranuclear palsy. CONCLUSIONS: Although neuroanatomical differences were identified between these distinctive clinical syndromes, substantial overlap was also observed, including midbrain atrophy, suggesting these two syndromes may have common pathophysiological underpinnings. PMID:23078273

202

Use of imaging techniques to predict progression in osteoarthritis.  

PURPOSE OF REVIEW: Disease progression of osteoarthritis is usually assessed using radiographs. Utilizing sensitive measures such as magnetic resonance imaging (MRI) may allow us to understand the progressive trajectory of this disease from initial to joint failure stages. This review aims to describe the recent epidemiological and clinical evidence about osteoarthritis disease progression and the risk factors associated with disease progression. RECENT FINDINGS: Changes in MRI-detected structural abnormalities, including increases in cartilage defects and bone marrow lesions (BMLs), loss of cartilage volume and thickness, and alterations of compositional measures, have been utilized to assess osteoarthritis disease progression. Both clinical risk factors (such as obesity or body fat, muscle weakness, malalignment, metabolic disorders, inflammation, and joint pain) and joint structural factors (such as cartilage defects, BMLs, meniscal pathology, synovitis, and radiographic features) have been associated with osteoarthritis disease progression. With the modification of these factors through interventions such as weight loss, we may slow the progression. SUMMARY: MRI techniques allow us to measure osteoarthritis disease progression and to discover novel risk factors for prevention and innovative strategies for treatment. These also allow identifying persons at greatest risk of disease progression, which may enhance the efficiency of clinical trials through reducing sample size and shortening follow-up period. PMID:23080226

203

Environment, Safety and Health Progress Assessment of the Argonne Illinois Site  

This report documents the results of the US Department of Energy (DOE) Environment, Safety and Health (ES&H) Progress Assessment of the Argonne Illinois Site (AIS), near Chicago, Illinois, conducted from October 25 through November 9, 1993. During the Progress Assessment, activities included a selective review of the ES&H management systems and programs with principal focus on the DOE Office of Energy Research (ER); CH, which includes the Argonne Area Office; the University of Chicago; and the contractor`s organization responsible for operation of Argonne National Laboratory (ANL). The ES&H Progress Assessments are part of DOE`s continuing effort to institutionalize line management accountability and the self-assessment process throughout DOE and its contractor organizations. The purpose of the AIS ES&H Progress Assessment was to provide the Secretary of Energy, senior DOE managers, and contractor management with concise independent information on the following: change in culture and attitude related to ES&H activities; progress and effectiveness of the ES&H corrective actions resulting from the previous Tiger Team Assessment; adequacy and effectiveness of the ES&H self-assessment process of the DOE line organizations, the site management, and the operating contractor; and effectiveness of DOE and contractor management structures, resources, and systems to effectively address ES&H problems and new ES&H initiatives.

204

Market assessment of photovoltaic power systems for agricultural applications worldwide  

Agricultural sector PV market assessments conducted in the Phillippines, Nigeria, Mexico, Morocco, and Colombia are extrapolated worldwide. The types of applications evaluated are those requiring less than 15 kW of power and operate in a stand alone mode. The major conclusions were as follows: PV will be competitive in applications requiring 2 to 3 kW of power prior to 1983; by 1986 PV system competitiveness will extend to applications requiring 4 to 6 kW of power, due to capital constraints, the private sector market may be restricted to applications requiring less than about 2 kW of power; the ultimate purchase of larger systems will be governments, either through direct purchase or loans from development banks. Though fragmented, a significant agriculture sector market for PV exists; however, the market for PV in telecommunications, signalling, rural services, and TV will be larger. Major market related factors influencing the potential for U.S. PV Sales are: lack of awareness; high first costs; shortage of long term capital; competition from German, French and Japanese companies who have government support; and low fuel prices in capital surplus countries. Strategies that may aid in overcoming some of these problems are: setting up of a trade association aimed at overcoming problems due to lack of awareness, innovative financing schemes such as lease arrangements, and designing products to match current user needs as opposed to attempting to change consumer behavior.

205

Energy assessment of Ivory Coast, Morocco, Nigeria, and Senegal  

This report is an overview of the energy market in four West African countries: The Ivory Coast, Morocco, Nigeria, and Senegal. We feel these countries are representative of the West African region. Together they account for 75% of the total energy use in West Africa, 78% of GDP, and 76% of population. The purpose of the study is to analyze the evolution of energy demand in the context of the general socio-economic background of the region. The study also examines energy supply and trade related to the energy sector. The analysis focuses on the study of commercial fuels. Although we have reviewed studies of wood, solar, wind, and agricultural residues, we leave out detailed discussions of these non-commercial energy forms. The first part of the report is an assessment of the trends in energy demand in the four study countries. We discuss the main factors driving energy demand sector by sector. This is followed by a review of the primary energy resources of the countries, and of the capacity for production of secondary fuels. The last section looks at energy trade, with particular emphasis on the role of the United States.

206

Instructional Technology in Higher Education: A Case of Selected Universities in the Niger Delta  

This article examines the effectiveness of instructional technology in higher education institutions in relation to the role and usage of Information Communication Technology (ICT), its effectiveness in faculty teaching and its impact on student learning in universities in the Niger Delta of Nigeria. This study applied the Need Assessment Approach (NAA). A self-designed questionnaire, that employed benchmarks from similar studies conducted in the West, was used to collect data for this study. One hundred and twenty five (n = 125) respondents participated in the study. The results suggest that there are significant relationships between the impact of instructional technology, the usage of instructional technology and students' academic achievement. An absence of ICT instructional materials, ineffective policy implementation and a lack of other resources (infrastructures) to aid teaching and learning are responsible for short comings in the effective implementation of ICT in education. The study revealed that experience makes it easier to employ and exhibit greater proficiency when using ICT instructional material in the teaching and learning process. The findings and nature of this study bare implications for higher education administrators, faculty and researchers. By design, this research was based on a narrow field of literature and a small sample size. Consequently, it is recommended that further studies are based on a more widespread survey of literature and a larger sample size, which might also involve multiple case studies. (Contains 3 figures and 3 tables.)

207

The dynamics of soil aggregate breakdown in water in response to landuse as measured with laser diffraction technique  

The Mastersizer 2000G (Malvern Instruments) Diffraction Instrument was used to assess and quantify the breakdown of soil aggregates and compute wet aggregate stability indices. The study was aimed at evolving a novel rapid method of determining soil aggregate stability. Bulk surface (0-15 cm) soil samples were collected under 5 different land uses in the Teaching and Resrach Farm of Obafemi Awolowo University, Ile-Ife, Nigeria. About 0.5g of the soils aggregates (0.5 -1 mm diameter) were evaluated in the laser diffractometer with the stirrer operated at 500 rpm and the pump at 1800 rpm. The different size aggregates and particles of sand silt and clay were quantified periodically. Water stable aggregates greater than 250 µm (WSA>250), water stable aggregates less than 250 µm (WSA250 was significantly higher on the soils under Forest (FR), Cacao (CC), Teak (TK) and Oil Palm (OP) plantations, while it was significantly lowest under no-tillage (NT) and continuous cultivation (CT). The pasture (PD) was not significantly different from either the cultivated and the non-cultivated soils. Conversely, the WSA250. The wet sieving water stable aggregates index (WSI>250) was significantly correlated with WSA>250 (r = 0.75), MVD (r = 0.75), WDI (r = -0.68) and WSA<250 (r = - 0.73). All the laser diffraction measured aggregation indices were significantly correlated with the organic matter contents of the soils. Thus the laser diffraction promises a rapid and comprehensive method of evaluation of soil aggregate stability.

208

Climate variability and environmental stress in the Sudan-Sahel zone of West Africa.  

Environmental change in the Sudan-Sahel region of West Africa (SSWA) has been much debated since the droughts of the 1970s. In this article we assess climate variability and environmental stress in the region. Households in Senegal, Mali, Burkina Faso, Niger, and Nigeria were asked about climatic changes and their perceptions were compared across north-south and west-east rainfall gradients. More than 80% of all households found that rainfall had decreased, especially in the wettest areas. Increases in wind speeds and temperature were perceived by an overall 60-80% of households. Contrary to household perceptions, observed rainfall patterns showed an increasing trend over the past 20 years. However, August rainfall declined, and could therefore potentially explain the contrasting negative household perceptions of rainfall trends. Most households reported degradation of soils, water resources, vegetation, and fauna, but more so in the 500-900 mm zones. Adaptation measures to counter environmental degradation included use of manure, reforestation, soil and water conservation, and protection of fauna and vegetation. The results raise concerns for future environmental management in the region, especially in the 500-900 mm zones and the western part of SSWA. PMID:22270527

209

Handling e-waste in developed and developing countries: Initiatives, practices, and consequences.  

Discarded electronic goods contain a range of toxic materials requiring special handling. Developed countries have conventions, directives, and laws to regulate their disposal, most based on extended producer responsibility. Manufacturers take back items collected by retailers and local governments for safe destruction or recovery of materials. Compliance, however, is difficult to assure, and frequently runs against economic incentives. The expense of proper disposal leads to the shipment of large amounts of e-waste to China, India, Pakistan, Nigeria, and other developing countries. Shipment is often through middlemen, and under tariff classifications that make quantities difficult to assess. There, despite the intents of national regulations and hazardous waste laws, most e-waste is treated as general refuse, or crudely processed, often by burning or acid baths, with recovery of only a few materials of value. As dioxins, furans, and heavy metals are released, harm to the environment, workers, and area residents is inevitable. The faster growth of e-waste generated in the developing than in the developed world presages continued expansion of a pervasive and inexpensive informal processing sector, efficient in its own way, but inherently hazard-ridden. PMID:22858354

210

Haemoglobin F levels in healthy Nigerian adults.  

Sickle Cell disease is a major genetic disorder in tropical Africa; its severity is often ameliorated by the presence of high levels of HbF, which is genetically determined. HbF was assessed in healthy Nigeria adults using the two minutes alkali denaturation method of Betke. The subjects studied included twenty-six males and twenty-four females all with HbA this was compared with twenty heterozygotes (HbAS). The mean HbF of the entire subject studied was 2.5 +/- 1.7% (range 0.4-12.8%). The mean value for Individuals with HbA genotype was 2.7 +/- 3.4% (range 0.4-12.8%). While the AS subject had a mean of 2.4 +/- 2.2% (range 0.7-8.4%). Twenty-two percent of the population studied had value greater than 3%. The high Level of HbF among healthy adults is believed to be genetic and related to the high prevalence of sickle cell disease in this sub-region. The association between HbF and high Persistence of fetal haemoglobin (HPFH) and the thalassaemias are discussed. PMID:14529224

211

Dissecting the dissectors: Knowledge, attitude, and practice of body bequests by Nigerian anatomists.  

Anatomy education in most African countries is limited by an insufficient number of cadavers for students to undertake dissection. This already significant shortage is exacerbated by an increasing number of medical schools and students. Virtual dissections are impractical in alleviating such a shortfall in African anatomy education, and further cadaver supply is challenged by unethical and dubious sources. This study was designed to assess the knowledge, attitudes, and practice of whole body and organ donation by Nigerian anatomists with the aim of finding solutions to the problems associated with the availability of cadavers in Nigerian medical schools. Out of 46 anatomists that participated in the survey, only 23.9% would consider donating their whole bodies and 60.9% their organs. More than 95% of respondents did not believe that body bequests could become the sole source of cadavers for anatomic dissection in Nigeria. Age and gender were not statistically significant in the choice of being a body or organ donor. The unacceptability to one's family members regarding body donation was the major reason for respondents' unwillingness to make a whole body donation. None of the 14 medical schools sampled in this study have yet instituted a body registration and donation program. The anatomists showed a high level of knowledge and awareness of body bequest programs, which were not reflected by their attitudes and practice. The authors recommend proactive measures aimed at improving the perception and attitudes of Nigerian anatomists. Anat Sci Educ. © 2012 American Association of Anatomists. PMID:22753151

212

Terrain Conductivity Evaluation of Road Base Integrity in a Basement Complex Environment  

A shallow electromagnetic evaluation of Federal University of Technology, Akure, Nigeria main road base integrity has been undertaken in this study with the aim of identifying probable zones of untimely failure. Controlled-Source Electromagnetic Method (CSEM) was adopted for the study. The road segment investigated is underlain by four different lithologic units, which are the migmatite gneiss, quartzites, charnockite and granites along the west-east direction of the campus. Quadrature phase (conductivity) and in-phase (magnetic susceptibility) were measured in both vertical and horizontal dipoles. While the vertical dipole mode has a probing depth of 6 m, the horizontal dipole mode probes at a depth of 3 m. The range of quadrature and in-phase values obtained for horizontal dipole mode is from 6 to 50 mS m-1 and 0.808 to 20.47 ppt, respectively. For vertical dipole mode, the range of quadrature and in-phase values are -21.00 -71.00 mS m-1 and -20.07 to 20.47 ppt. The ratio of vertical conductivity value (CV) to horizontal conductivity value (CH) i.e., CV/CH was utilized in assessing road-base performance. Road stability was observed where this ratio is greater than 1 (CV/CH>1) while signs of distress characterized where the ratio is less than or equal to 1 (CV/CH = 1) in vertical dipole. Likewise, relatively high magnetic susceptibility values in vertical dipole mode characterized zones of early distress. This technique is presumed useful in fast and cheap roadwork performance evaluation.

213

Prospects and Challenges of Online Guidance and Counselling Services in a Nigerian University  

This study examined the prospects and challenges of online guidance and counselling services at the Obafemi Awolowo University, Ile-Ife, Nigeria. It considered students' views on the nature of and preferences for online services, and the problems that might potentially be presented in that context. It also surveyed staff in regard to assessing the human and material resources available for offering such services. Two hundred students were selected by random sampling at the eight cybercafes on the University campus. Also, one hundred staff members were purposively selected, consisting of technical experts, trained counsellors and other academic and non-academic staff members. Data were collected through separate questionnaires for students and staff on the "Prospects of Online Guidance and Counselling services at OAU." Data were analyzed using descriptive analysis, Relative Significance Index, factor analysis and cluster analysis. The results showed that students identified potential online guidance and counselling needs as being mainly related to academic/educational interests; specifically, career planning, problem-solving skills and acquiring effective study skills. Sexual issues as well as dating and relationship issues came last on the list of the 12 potential online counselling needs identified. Most of the students (89.5%) had favourable perceptions towards the possible establishment of online guidance and counselling services in the University. Results from staff responses identified some significant limitations in terms of current human and material resources, with these needing to be rectified if the University was to offer online counselling and guidance services.

214

Evaluation of HIV/AIDS Secondary School Peer Education in Rural Nigeria  

In this study, we assessed whether peer education is an effective method of HIV/AIDS awareness, in terms of knowledge, misconception and behavior, among adolescents in the rural area of Nigeria. A comparative case series (n = 250), cross-sectional structured survey (n = 135) and focus group discussions (n = 80) were undertaken among adolescents. In both the case series and structured survey, a questionnaire was used which addresses the following issues: socio-demography, knowledge on transmission and prevention of HIV/AIDS, accessibility to different sources of HIV/AIDS information, stigmatization and sexual behavior. Binary logistic regression was applied to compare responses from the peer-educated and not peer-educated populations. The model was adjusted for confounders. We demonstrated increased knowledge and decreased misconception and sexual risk behavior in adolescents receiving peer education as compared to adolescents not receiving peer education. These differences are apparent both over time (2005-2007) and cross-sectional (2007). In conclusion, peer education in rural areas can be effective in HIV/AIDS prevention. Knowledge and behavior can be influenced positively.

215

Evaluation of HIV/AIDS secondary school peer education in rural Nigeria.  

In this study, we assessed whether peer education is an effective method of HIV/AIDS awareness, in terms of knowledge, misconception and behavior, among adolescents in the rural area of Nigeria. A comparative case series (n = 250), cross-sectional structured survey (n = 135) and focus group discussions (n = 80) were undertaken among adolescents. In both the case series and structured survey, a questionnaire was used which addresses the following issues: socio-demography, knowledge on transmission and prevention of HIV/AIDS, accessibility to different sources of HIV/AIDS information, stigmatization and sexual behavior. Binary logistic regression was applied to compare responses from the peer-educated and not peer-educated populations. The model was adjusted for confounders. We demonstrated increased knowledge and decreased misconception and sexual risk behavior in adolescents receiving peer education as compared to adolescents not receiving peer education. These differences are apparent both over time (2005-2007) and cross-sectional (2007). In conclusion, peer education in rural areas can be effective in HIV/AIDS prevention. Knowledge and behavior can be influenced positively. PMID:18990683

216

Concurrent urinary and intestinal schistosomiasis and intestinal helminthic infections in schoolchildren in Ilobu, South-western Nigeria.  

A cross-sectional study was conducted in a schistosome-endemic rural community in Southwestern Nigeria. We assessed prevalence and intensity of soil-transmitted nematodes and the co-occurrence with Schistosoma haematobium and Schistosoma mansoni. Urine and stool samples from 419 schoolchildren were examined, and a questionnaire was administered to obtain socio-demographic characteristics. In total, 78.3% (328/419) were infected with at least one helminth species, with a prevalence (mean egg-count) of 55.1% (3069.2) of Ascaris lumbricoides, 41.1% (127.5) of S. haematobium, 22.7% (98.6) of hookworms, 17.9% (161.3) of Trichuris trichiura, and 10.3% (12.9) of S. mansoni. Multiple infections were significantly more common among children from households with more playmates, absence of toilet facilities and low income level (all plumbricoides infections was increased in co-infections with S. haematobium. Logistic regression analysis revealed infections by hookworms and S. mansoni (adjusted odds ratio [aOR]=3.90, 95% Cl: 2.03-7.46; p<0.0001), and by hookworms and T. trichiura (aOR=2.46, 95% Cl: 1.44-4.22; p=0.001) as significant risk factors for multiple infections. Our study shows that polyparasitism is common in the study area. Focused interventions such as mass treatment with anthelminthics and health education are needed to improve the well-being of the affected population. PMID:22440198

217

Risk for tuberculosis among children  

Contacts of adults with tuberculosis (TB) are at risk for infection. Tests based on interferon-gamma (IFN-gamma) expression in response to Mycobacterium tuberculosis antigens may be more sensitive than the tuberculin skin test (TST). Risk for infection was assessed by using TST and an IFN-y-based assay (QuantiFERON Gold in Tube [QFT-IT] test) for 207 children in Nigeria in 1 of 3 groups: contact with adults with smear-positive TB, contact with adults with smear-negative TB, and controls. For these 3 groups, respectively, TST results were >10 mm for 38 (49%) of 78, 13 (16%) of 83, and 6 (13%) of 46 and QFT-IT positive for 53 (74%) of 72, 8 (10%) of 81, and 4 (10.3%) of 39 (p < 0.01). Most test discrepancies were TST negative; QFT-IT positive if in contact with TB-positive persons; and TST positive, QFT-IT negative if in contact with TB-negative persons or controls. TST may underestimate risk for infection with TB in children.

218

Rubber dam use among a subpopulation of Nigerian dentists  

In this cross-sectional questionnaire-based study, we surveyed the attitudes toward, knowledge of, and use of rubber dams (RDs) among dentists in southern Nigeria. The questionnaire, which was distributed and collected by one of the authors, requested information on the dentists' background characteristics, attitudes, and knowledge. Data were analyzed with SPSS, and the chi-square was used to assess differences in categorical variables. A total of 100 out of 108 dentists responded (92.6% response rate). The prevalence of RD use was 18%. Dentists in the government sector used RDs more often than did dentists in the private sector. About 77% of dentists had not used RDs or were unaware of how to use them. All specialists had seen RDs, but only 56% had used one in their practice. All dentists believed in the effectiveness of RDs. We conclude that rubber dams are underutilized in this population, and that dentists need to be made aware of the possibility of rubber dam use through an awareness campaign. (J Oral Sci 52, 245-249, 2010)   

219

Recycling of organic wastes through composting for land applications: a Nigerian experience.  

In-vessel composting, a contribution to sustainable solid waste management, was conducted on source-separated waste materials generated in Abeokuta city, south-west Nigeria. Feedstock (household, agricultural and municipal waste) and the resultant composts were chemically characterized using standard procedures. Identification and changes in the microbial population during composting, the effects of composting on waste volume reduction (WVR) and elemental composition of composts were evaluated. Product performance on plant growth and metal uptake were then assessed using African spinach (Amaranthus hybridus) in a screen house for 8 weeks. Metals were determined in acid digest using atomic absorption spectrometry. Compost yields and WVR ranged from 35.28 to 48.68% and 51.66 to 64.72%, respectively. Compost heavy metal (Cu, Cr, Zn, Ni, Cd and Pb) concentrations (mg kg( -1)), ranging from 0.67-0.82; 0.13-7.5; 0.001-0.22; 1.67-18.33; 6.50-17.67; and 0.83-6.00 for Cu, Pb, Cd, Ni, Cr and Zn, respectively, were within limits for class A+ composts. The effect of composting varied with element type and significantly (p waste management option in the developing countries. PMID:21159738

220

Assessment of dental waste management in a Nigerian tertiary hospital.  

This study assessed the practice of disposing of waste from the eight dental clinics of Obafemi Awolowo University Teaching Complex, Ile-Ife, Nigeria. All the cleaners (14) in the hospitals were surveyed through questionnaire. Information obtained from the cleaners included socio-economic characteristics (biodata), personal protection, facilities available for them to work with and job satisfaction. Two soil samples were obtained from the open dump site (0.15 and 0.30 m depth) and two water samples were also collected (at 0.00 and 50.00 m) within the vicinity of the dump site. Both the soil and water samples were taken to the central science laboratory for chemical analyses. Ten (71.4%) of the 14 cleaners were not satisfied with their job. The laboratory findings suggested a very high content of lead, chromium, mercury, cadmium and manganese in both soil and water samples in comparison with the Nigerian Federal Environmental Protection Agency standards. The study concludes that the use of tooth-coloured restorative materials and digital X-ray facility to serve as alternatives to the generation of these wastes is recommended and that farming activities should not be allowed in the area until an audit of the soil and water have been performed. PMID:20124316

 
 
 
 
221

Creating a strong working relationship between the governments and the Community for Sustainable Development of Ibadan City, Nigeria.  

This article describes the Sustainable Cities Program in Ibadan City, Nigeria. The program began in 1994, with an Environmental Planning and Management approach as part of the Sustainable Ibadan Project (SIP). The aim was to involve stakeholders in assessment and priority setting on urban environmental issues. Stakeholders include government officials, community leaders, people and organizations in the private sector, and international agencies. Stakeholders were sensitized and mobilized about the SIP through formal/informal meetings and well-organized sectoral briefings on trade, health, business, education, transportation, and traditional rulers. Stakeholders were asked to identify, articulate, clarify, and prioritize environmental issues in Ibadan. This approach led to changes in the way sectors identified issues and problems. A 1995 City Consultation among stakeholders led to a Declaration that identified and prioritized environmental issues. Multisectoral and interorganizational working groups were set up to address issues of waste recycling, water supply, and environmental sanitation in Bodija Market, and the Odo-Akeu Spring Water Development Project. The spring water project led to the development of a plan to enhance supply of hygienic water in a densely developed, unplanned area of the city. Project outcomes included the mobilization of human and financial resources that previously were unavailable. The project was successful in mobilizing apathetic communities to work with local governments to jointly develop action plans, ensuring healthy sustainable development. PMID:12178495

222

An in vivo evaluation of induction of abnormal sperm morphology in mice by landfill leachates.  

Although several reports have demonstrated the acutely toxic and genotoxic effects of landfill leachates in microbial organisms, plants and aquatic animals, the effects of pollutants present in these leachates have not been clarified yet in terrestrial animals. This study mainly aimed to evaluate a potential genetic effect of raw and simulated leachates from Orita-Aperin and Oworonsoki landfills in south-west Nigeria by use of the murine sperm-head abnormality test. These landfills neither have a synthetic membrane liner at the bottom, nor a natural layer of compacted soil with the desired hydraulic conductivity, nor a run-off control system. As a result, the leachates produced are discharged into the environment. Samples designated as Orita-Aperin Raw Leachate (OARL), Orita-Aperin Simulated Leachate (OASL), Oworonsoki Raw Leachate (OWRL) and Oworonsoki Simulated Leachate (OWSL) were analyzed in the sperm-head abnormality test at concentrations (v/v) of 1%, 2.5%, 5%, 10% and 25%. Mice were given 0.5 ml sample per day for five consecutive days by intraperitoneal injection. Each dose group comprised seven mice, and a 5-week exposure period was utilized. The data show that the test mixtures induced a dose-dependent, statistically significant increase (Pwaste management, and for the assessment of the hazardous effects of the chemicals in landfill leachates. PMID:15781207

223

Children with paralytic poliomyelitis: Utilization of physiotherapy services in Zamfara State, Nigeria.  

Physiotherapy is usually indicated for health promotion and the rehabilitation of individuals with paralytic poliomyelitis. The endemic nature of this condition in children in Zamfara State, Nigeria necessitated investigation into the utilization of physiotherapy services by parents or primary caregivers of children affected with polio in this sub-region. Parents and primary caregivers of children with paralytic poliomyelitis were recruited using a purposive multi-stage sampling procedure in a cross-sectional survey. Factors associated with the utilization of physiotherapy services were assessed based on questions extracted from a 4-part, 52-item structured questionnaire originally designed for a study which investigated knowledge, attitude, and beliefs of parents of children with paralytic poliomyelitis. A total of 217 participants were included in this study. The mean age was 32.29?±?9.89 years and the mean knowledge of polio score was 62.0?±?17.3%. The mean age of the children with paralytic poliomyelitis was 6.41?±?2.50 years. Only 27.2% of the parents or primary caregivers had utilized physiotherapy service for their children at some point. No association existed between utilization of physiotherapy service and 'knowledge of paralytic poliomyelitis', 'employment status', and 'family income' of respondents. Explanations for low utilization of physiotherapy services for children with paralytic poliomyelitis by parents or primary caregivers are discussed. PMID:22871225

224

A Systematic Review of Behavioral Interventions to Prevent HIV Infection and Transmission among Heterosexual, Adult Men in Low-and Middle-Income Countries.  

Prevention of new HIV infections needs to move to the forefront in the fight against HIV and AIDS. In the current economic crisis, low- and middle-income countries (LMICs) should invest limited resources to amass reliable evidence-based information about behavioral prevention efforts, and on behaviors that are driving the epidemic among people who are engaging in those behaviors. This paper aims to provide a systematic review and synthesis of behavioral interventions among a group of people in high HIV-burden countries: heterosexual men in LMICs. The review includes articles published between January 2001 and May 2010 that evaluated behavioral prevention interventions among heterosexual males aged 18+ years in LMICs. The studies were evaluated using the quality assessment tool for quantitative studies developed by the Effective Public Health Practice Project. The review identified 19 articles that met the review's inclusion criteria. Most studies were conducted in South Africa (n=6); two each in Uganda and Thailand; and one in each of Angola, Brazil, Bulgaria, India, Nigeria, the Philippines, Russia, Ukraine and Zimbabwe. Eight of 19 interventions increased condom use among their respective populations. Those interventions that sought to reduce the number of sexual partners had little effect, and those that addressed alcohol consumption and intimate partner violence had mixed effects. There was no evidence for any specific format of intervention that impacted best on any of the targeted risk behaviors. The paucity of evaluated interventions for heterosexual men in LMICs suggests that adult men in these countries remain underrepresented in HIV prevention efforts. PMID:23111548

225

`Once more unto the breach, dear friends'. Editorial Introduction  

In introducing his Special Issue, the guest-editor identifies different usages of the term `UPE', also reflected in the contributions to the Issue, and comments on the implications of this diversity in the context of nations' efforts to achieve it. `Real' and `bogus' UPE are distinguished and the alternative concept of basic education considered. Implementation of UPE, an immensely demanding undertaking, requires adequate information, genuine commitment and close co-operation — at all levels and from all concerned; equally, it depends on administrative ability, organization of training, and political motivation, flexibility and sincerity. Recognising the demands and costs of UPE, the reasons for commitment to it are examined (and illustrated from the case of Nigeria) — and the feasibility of successful implementation, e.g., by the year 2000, assessed. Alternatives exist, both in concept and practice, but seem unlikely to commend themselves. Nevertheless, as is stressed in the articles, lessons may be learned from experience already gained concerning the effectiveness of such factors as: greater community involvement in providing and controlling schools; more emphasis on school health; closer relationships between central and local planning; alternative structures for older learners or drop-outs; the shortening of instructional time; and increased research and greater investment in training for the teaching of basic skills at primary level. Without a radical change of attitude, particularly with respect to this last priority, efforts to achieve even literacy, the first goal of UPE, are being seriously undermined.

226

What Do Expectant Mothers Know about Neonatal Jaundice?  

Neonatal jaundice (NNJ) is a common disorder worldwide and many affected babies become brain-damaged due to delay in seeking medical consultation. In order to assess the awareness and knowledge of expectant mothers about NNJ, women who registered for antenatal care at a tertiary health facility in the South-western part of Nigeria were consecutively recruited and interviewed by means of a questionnaire. There were 189 participants whose mean age was 30.1 plus or minus 5.2 years. Median parity was 2. Twenty-five (13.2%) of them completed primary education while 88 (46.6%) attended a tertiary institution. All the 189 participants have heard of NNJ, mainly from co-workers - 77 (40.7%) and hospital staff - 73 (38.6%). One hundred and seven respondents (56.6%) knew how to check a baby for NNJ correctly while only 12.2% knew some causes. Ninety-five (49.7%) did not know any danger sign of NNJ and 58 (30.7%) erroneously believed in the efficacy of drugs. Similarly 28 (14.8%) respondents wrongly believed in the use of unproven local remedy. None of the 189 would-be mothers knew any effective preventive measure. It is concluded that expectant mothers do not have adequate knowledge about NNJ. This can hinder effective management of jaundice in their unborn children. Greater public enlightenment campaign is recommended. (Contains 2 tables.)

227

Environment, Safety and Health Progress Assessment of the Hanford Site  

This report documents the result of the US Department of Energy (DOE) Environment, Safety and Health (ES&H) Progress Assessment of the Hanford Site, in Richland, Washington. The assessment, which was conducted from May 11 through May 22, 1992, included a selective-review of the ES&H management systems and programs of the responsible DOE Headquarters Program Offices the DOE Richland Field Office, and the site contractors. The ES&H Progress Assessments are part of the Secretary of Energy`s continuing effort to institutionalize line management accountability and the self-assessment process throughout DOE and its contractor organizations. The purpose of the Hanford Site ES&H Progress Assessment is to provide the Secretary with an independent assessment of the adequacy and effectiveness of the DOE and contractor management structures, resources, and systems to address ES&H problems and requirements. They are not intended to be comprehensive compliance assessments of ES&H activities. The point of reference for assessing programs at the Hanford Site was, for the most part, the Tiger Team Assessment of the Hanford Site, which was conducted from May 21 through July 18, 1990. A summary of issues and progress in the areas of environment, safety and health, and management is included.

228

Rapid assessment method for prevalence and intensity of Loa loa infection/ Méthode d'évaluation rapide de la prévalence et de l'intensité des infections à Loa loa/ Método de evaluación rápida de la prevalencia e intensidad de la infección por Loa loa  

Abstract in spanish OBJETIVO: Evaluar la validez de las observaciones de Loa loa a nivel ocular y de la tumefacción de Calabar como criterios de evaluación rápida de la prevalencia e intensidad de la loasis a nivel de la comunidad. MÉTODO: Participaron en el estudio 12 895 individuos mayores de 15 años de 102 comunidades de aldeas del Camerún y Nigeria. Se distribuyó entre los participantes un cuestionario normalizado y se les extrajeron muestras de sangre por punción digital para de (more) terminar la presencia de microfilarias de Loa loa. La evaluación rápida de la prevalencia e intensidad de la loasis se hizo a partir de los antecedentes de afectación ocular o de tumefacción de Calabar. RESULTADOS: Se observó una estrecha correlación entre los índices deparados por los procedimientos de evaluación rápida y los índices parasitológicos de endemicidad por L. loa. Los índices de evaluación rápida permiten identificar las comunidades de alto riesgo (sensibilidad: 94%-100%; especificidad: 66%-92%). La sensibilidad y especificidad más altas (100% y 79%-92%, respectivamente) se obtuvieron con el procedimiento de evaluación rápida basado en el criterio de unos antecedentes de afectación ocular de 1-7 días de duración, confirmados por el reconocimiento guiado, en una fotografía, de una filaria adulta de L. loa en el ojo. CONCLUSIÓN: Es posible efectuar una evaluación rápida de la prevalencia y la intensidad de la loasis a nivel comunitario utilizando como criterio la observación del nematodo en el ojo por espacio de uno a siete días, confirmada por el reconocimiento guiado, en una fotografía, de un ejemplar adulto de L. loa en el ojo. Abstract in english OBJECTIVE: To assess the validity of observations on eye worm and Calabar swellings for the rapid assessment of the prevalence and intensity of loiasis at the community level. METHOD: A total of 12 895 individuals over the age of 15 years living in 102 communities in Cameroon and Nigeria took part in the study. A standardized questionnaire was administered to participants from whom finger-prick blood samples were collected and examined for Loa loa microfilariae. Rapid ass (more) essments of the prevalence and intensity of loiasis were made on the basis of a history of eye worm or Calabar swellings. FINDINGS: There was a strong correlation between the indices of the rapid assessment procedures and the parasitological indices of L. loa endemicity. The rapid assessment indices were effective in diagnosing high-risk communities (sensitivity 94-100%; specificity 66-92%). The highest sensitivity (100%) and specificity (92%) were obtained with a rapid assessment procedure based on a history of eye worm lasting 1-7 days together with confirmation by the guided recognition of a photograph of adult L. loa in the eye. CONCLUSION: Rapid assessment of the prevalence and intensity of loiasis at the community level can be achieved using a procedure based on the history of eye worm lasting 1-7 days together with confirmation by the guided recognition of a photograph of an adult L. loa in the eye.

229

Health and Safety Research Division. Progress report, October 1, 1979-March 31, 1981  

Research progress for the period October 1, 1979 through March 31, 1981 is reported. Research conducted by the Office of Integrated Assessments and Policy Analysis, Health Studies Section, Technology Assessments Section, Biological and Radiation Physics Section, and Chemical Physics Section is summarized. (ACR)

230

Uranium recovery research sponsored by the Nuclear Regulatory Commission at Pacific Northwest Laboratory. Quarterly progress report, June-September 1983  

This report documents progress for the following major research projects: stabilization, engineering, and monitoring alternatives assessment for improving regulation of uranium recovery operations and waste management; attenuation of radon emission from uranium tailings; assessment of leachate movement from uranium mill tailings; and methods of minimizing ground-water contaminants from in-situ leach uranium mining.

231

From toxic releases to damages on human health: a method for life cycle impact assessment, with a case study on domestic rainwater use  

Life Cycle Assessment (LCA) is a tool developed to evaluate the environmental impact of a product or a system. After a decade of research in the LCA field, significant progress has been achieved but methodologies for the assessment of toxicological impacts on human health are still in the developmen...

232

On Reliability Based Optimal Design of Concrete Bridges  

In recent years important progress has been made in assessment of the lifetime behaviour of concrete bridges. Due to the large uncertainties related to the loading and the deterioration of such bridges, an assessment based on stochastic modelling of the significant parameters seems to be only releva...

233

Development of nondestructive-evaluation techniques for high-temperature ceramic heat-exchanger components. Semiannual report, October 1980-March 1981  

During this reporting period, progress has been made in the development of the ultrasonic bore-side probe, application of acoustic microscopy techniques to ceramic joint assessment, quantification of holographic interferometry to obtain flaw-size information, and evaluation of rod anode microfocus radiography for ceramic butt joint assessment.

234

Analysis of synthetic lubricating oils based on esters by gas chromatography-CI(NH/sub 3/)-mass spectrometry  

For product control and quality assessment of ester oils efficient analytical methods are needed. This is especially true for the assessment of used oils. It is shown with neopentylpolyol ester oils that capillary gas chromatography in combination with chemical ionization (NH/sub 3/)-mass spectrometry presents a considerable progress in the characterization of complex ester oils and their additive systems.

235

Reservoir compartmentalization of deep-water Intra Qua Iboe sand (Pliocene), Edop field, offshore Nigeria  

An integration of 3-D seismic and sedimentological information provides a basis for recognizing and mapping individual flow units within the Intra Qua Iboe (IQI) reservoir (Pliocene), Edop Field, offshore Nigeria. Core examination show the following depositional facies: A-Sandy slump/mass flow, B-Muddy slump/mass flow, C. Bottom current reworking. D-Non-channelized turbidity currents, E. Channelized (coalesced) turbidity currents. F-Channelized (isolated) turbidity currents, G-Pelagic/hemipelagic, H-Levee, I-Reworked slope, J-Wave dominated, and K-Tide dominated facies. With the exception of facies J and K, all these facies are of deep-water affinity. The IQI was deposited on an upper slope environment in close proximity to the shelf edge. Through time, as the shelf edge migrated scaward, deposition began with a channel dominated deep-water system (IQI 1 and 2) and progressed through a slump/debris flow dominated deep-water system (IQI 3, the principle reservoir) to a tide and wave dominated shallow-water system (IQI 4). Compositional and textural similarities between the deep-water facies result in similar log motifs. Furthermore, these depositional facies are not readily apparent as distinct seismic facies. Deep-water facies A, D, E, and F are reservoir facies, whereas facies B, C, G, H, and I are non-reservoir facies. However, Facies G is useful as a seismically mappable event throughout the study area. Mapping of these non-reservoir events provides the framework for understanding gross reservoir architecture. This study has resulted in seven defined reservoir units within the IQI, which serves as the architectural framework for ongoing reservoir characterization.

236

Slump dominated upper slope reservoir facies, Intra Qua Iboe (Pliocene), Edop Field, offshore Nigeria  

An integration of sedimentologic and 3D seismic data provides a basis for unraveling complex depositional processes and sand distribution of the Intra Qua Iboe (IQI) reservoir (Pliocene), Edop Field, offshore Nigeria. Nearly 3,000 feet of conventional core was examined in interpreting slump/slide/debris flow, bottom current, turbidity current, pelagic/hemipelagic, wave and tide dominated facies. The IQI was deposited on an upper slope in close proximity to the shelf edge. Through time, as the shelf edge migrated seaward, deposition began with a turbidite channel dominated slope system (IQI 1 and 2) and progressed through a slump/debris flow dominated slope system (IQI 3, the principal reservoir) to a tide and wave dominated, collapsed shelf-edge deltaic system (IQI 4). Using seismic time slices and corresponding depositional facies in the core, a sandy {open_quotes}fairway{open_quotes} has been delineated in the IQI 3. Because of differences in stacking patterns of sandy and muddy slump intervals, seismic facies show: (1) both sheet-like and mounded external forms (geometries), and (2) parallel/continuous as well as chaotic/hummocky internal reflections. In wireline logs, slump facies exhibits blocky, coarsening-up, fining-up, and serrated motifs. In the absence of conventional core, slump facies may be misinterpreted and even miscorrelated because seismic facies and log motifs of slumps and debris flows tend to mimic properties of turbidite fan deposits. The slump dominated reservoir facies is composed of unconsolidated fine-grained sand. Thickness of individual units varies from 1 to 34 feet, but amalgamated intervals reach a thickness of up to 70 feet and apparently form connected sand bodies. Porosity commonly ranges from 20 to 35%. Horizontal permeability commonly ranges from 1,000 to 3,000 md.

237

The story of iodine deficiency: An international challenge in nutrition  

Iodine deficiency is a risk factor for the growth and development of up to 800 million people living in iodine deficient environments throughout the world. The effects on growth and development, called the iodine deficiency disorders (IDD), comprise goiter, stillbirths and miscarriages, neonatal and juvenile thyroid deficiency, dwarfism, mental defects, deaf mutism, and spastic weakness and paralysis, as well as lesser degrees of loss of physical and mental function. All these effects are due to inadequate thyroid hormone production because iodine is an essential constituent of the thyroid hormone. In the West, IDD has been largely eliminated by the addition of iodine to the diet through iodized salt or through changes in food distribution and technology. IDD still persists in certain areas of Europe where these dietary changes have not occurred. In the Third World, IDD is a major problem in many countries with large populations, such as China, India, Indonesia, Nigeria, and Zaire. In these and other Third World countries, IDD is a significant barrier to social and economic progress which can be removed by correction of the deficiency. This book shows that elimination of iodine deficiency is feasible within the next decade, only requiring a modest financial and technical effort from the West. Part 1 reviews IDD in man and animals. Part 2 discusses the control of iodine deficiency disorders through iodine supplementation, and considers action at the national and international level. Part 3 presents a global review of the status of IDD control. There is a brief conclusion on the way forward to successful control programs.

238

The burden of Neglected Tropical Diseases in Ethiopia, and opportunities for integrated control and elimination.  

ABSTRACT: BACKGROUND: Neglected tropical diseases (NTDs) are a group of chronic parasitic diseases and related conditions that are the most common diseases among the 2.7 billion people globally living on less than US$2 per day. In response to the growing challenge of NTDs, Ethiopia is preparing to launch a NTD Master Plan. The purpose of this review is to underscore the burden of NTDs in Ethiopia, highlight the state of current interventions, and suggest ways forward. RESULTS: This review indicates that NTDs are significant public health problems in Ethiopia. From the analysis reported here, Ethiopia stands out for having the largest number of NTD cases following Nigeria and the Democratic Republic of Congo. Ethiopia is estimated to have the highest burden of trachoma, podoconiosis and cutaneous leishmaniasis in sub-Saharan Africa (SSA), the second highest burden in terms of ascariasis, leprosy and visceral leishmaniasis, and the third highest burden of hookworm. Infections such as schistosomiasis, trichuriasis, lymphatic filariasis and rabies are also common. A third of Ethiopians are infected with ascariasis, one quarter is infected with trichuriasis and one in eight Ethiopians lives with hookworm or is infected with trachoma. However, despite these high burdens of infection, the control of most NTDs in Ethiopia is in its infancy. In terms of NTD control achievements, Ethiopia reached the leprosy elimination target of 1 case/10,000 population in 1999. No cases of human African trypanosomiasis have been reported since 1984. Guinea worm eradication is in its final phase. The Onchocerciasis Control Program has been making steady progress since 2001. A national blindness survey was conducted in 2006 and the trachoma program has kicked off in some regions. Lymphatic Filariasis, podoconiosis and rabies mapping are underway. CONCLUSION: Ethiopia bears a significant burden of NTDs compared to other SSA countries. To achieve success in integrated control of NTDs, integrated mapping, rapid scale up of interventions and operational research into co implementation of intervention packages will be crucial. PMID:23095679

239

Progressive muscle relaxation in persons with schizophrenia: a systematic review of randomized controlled trials.  

Objective:The aim of this systematic review was to assess the effectiveness of progressive muscle relaxation on psychological distress and anxiety symptoms and on response/remission for people with schizophrenia.Methods:Randomized controlled trials were considered if they investigated progressive muscle relaxation in patients with schizophrenia. EMBASE, PsycINFO, PubMed, ISI Web of Science, CINAHL, PEDro and Cochrane Library were searched. The selection of studies, data extraction and quality assessment were performed independently by two reviewers.Results:Three randomized controlled trials involving 146 patients met the inclusion criteria. Progressive muscle relaxation can acutely reduce state anxiety and psychological distress and improve subjective well-being. No studies investigated the evidence for progressive muscle relaxation as an add-on treatment for general psychopathology and for positive or negative symptoms. Also, no studies assessed the value of progressive muscle relaxation in longer-term treatment and for relapse prevention. There were no data to draw any conclusions about progressive muscle relaxation in comparison with other treatment modalities. None of the studies encountered adverse events. Dose-response relationships could not be determined.Conclusion:Progressive muscle relaxation might be a useful add-on treatment to reduce state anxiety and psychological distress and improve subjective well-being in persons with schizophrenia. PMID:22843353

240

Nigeria's Satellite Programme Development: Prospects and Challenges  

Nigeria's desire to maximize the benefits of space technology for its sustainable development, has become a reality with the establishment of the National Space Research and Development Agency (NASRDA) in May 1999 and the approval of the national Space Policy and Programmes in July 2001. In November, 2000, the Federal Government took a bold step with the signing of an agreement with the Surrey Satellite Technology Limited (SSTL) of United Kingdom (UK) for the design, construction and launch of a medium resolution micro-satellite - NigeriaSat-1 with a Ground Sampling Distance of thirty-two (32) meters. The agreement also covers the Know-How-Technology-Training (KHTT) to Nigerian Engineers and Scientists for a period of 18th months at SSTL‘s facility in the U.K.. NigeriaSat-1 was successfully launched into Leo Earth Orbit on 27th September, 2003. NigeriaSat- 1 is one of the five (5) satellites belonging to Nigeria, Algeria, Turkey, United Kingdom and China being operated in a Disaster Monitoring Constellation (DMC). The launch of NigeriaSat-1 has promoted access to information which has become a strategy for mass socio-economic development, as information underscores all developmental effort be it in education, provision of health services, marketing, construction industry, tourism, defense, etc. As a follow-up to the successful launch of NigeriaSat-1, the government of Nigeria started the implementation of a Nigerian communication satellite (NigcomSat-1) to address the problem of communication which is the greatest drawbacks to the socio-economic development of the country, particularly in the areas of rural telephone, tele-education, tele-medicine, egovernment, e-commerce and real-time monitoring services. NigcomSat-1, which carries 40- hybrid transponders in the C, KU, KA and L bands, has a 15 years life span and coverage of the African continent, Middle East and part of Europe was launched in May 2007. To satisfy geospatial data needs in sectors such as survey, housing, defence and security and urban renewal, and large scale mapping community, NASRDA has embarked on the development of a higher resolution satellite NigeriaSat-2 which carries spatial resolution pay loads of 2.5 and 5 meters in panchromatic and multi-spectral bands respectively. In addition, the satellite has been designed to provide stereo-imaging capability. It also carries a 32m resolution payload to ensure the continuity of NigeriaSat-1 data beyond its 2008 lifespan. The launch of NigeriaSat-2 is being planned for 2009. Furthermore, Nigeria's concern over the incessant cloud cover of a large area of its southern part has informed NASRDA's quest to acquire capacity for SAR-based image interpretation and application to socio-economic development. The programme will eventually lead to the acquisition of a SAR-based micro-satellite (NigeriaSat-3) in the near future.

 
 
 
 
241

Ethnicity, petroeconomy, and national integration in Nigeria  

Among several related phenomena, this study presents as its focal points the examination of some of the variables that influence and shape the structure of sociopolitical, cultural and socioeconomic relations in the course of national integration in Nigeria. The exploitation of petroleum resources since 1958 in the Niger Delta has largely influenced the course of the political as well as the socioeconomic development of Nigeria. Due to its rich petroleum resources, the Rivers territory ranked high in the political calculus of both the Federal Government and secessionist Biafra. The central thesis of this study is that oil is the single glue that has held the Federation of Nigeria together in the last two decades, and prevented it from being balkanized. This study attempts to put into perspective the various eruptions and episodes of secessionist tendencies and agitations in Nigeria. The ebb and flow of separatist agitations seem to reflect the changing geoeconomic, socioeconomic, and sociopolitical environment of the country. Should the petroeconomy collapse, and/or oil losses its significance in the international economy, what will happen to Nigeria as a nation. The present study points up the need to develop other sources of economic interdependence via the proper utilization of the enormous oil revenues before it is written off as a lost opportunity.

242

Resources, environment and economic development in Nigeria.  

It is argued that Nigeria must focus on effective environmentally protective intensive farming, resource management methods, and strong family planning programs. Other contributory factors are recognized as the lack of democracy and the "ill-advised" internal policies of the government. The emphasis is on man-made decisions about migration, natality, and land use practices that have ecological consequences that significantly affect the economy. Land degradation in Nigeria is attributed to improper agricultural and husbandry practices. Land degradation has severe ecological, economic, and human costs. Awareness of environmental problems in Nigeria is growing. Natural disasters such as the droughts of 1984-85, continued soil depletion, accumulations of soil wastes, increased flooding in urban areas, and land erosion in Anambra state are evidence of the growing environmental problems. Agricultural development should involve changing rural land use practices, using technology that is "appropriate" to the climate, crops, and culture of the people, and introducing agroforestry. Population growth in Nigeria puts pressure on the fragile ecosystem. Actual carrying capacity is a rough calculation. Nigeria's population growth patterns follow a pattern that suggests population pressure on carrying capacity. The acceleration of population growth has strained the traditional system of agriculture. Land is overused, and cultivation continues on unsuitable land. Domestic policies during the oil boom encouraged rapid industrialization at the expense of the environment. Migration increased to urban centers, but cities did not provide suitable housing, waste disposal, safe water supplies, and other basic facilities. PMID:12347030

243

Maintaining the uranium resources data system and assessing the 1991 US uranium potential resources. Final report  

The Energy Information Administration`s (EIA) Uranium Resource Assessment Data (URAD) System contains information on potential resources (undiscovered) of uranium in the United States. The purpose of this report is: (1) to describe the work carried out to maintain and update the URAD system; (2)to assess the 1991 U.S. uranium potential resources in various cost categories; and (3) to describe the progress that has been made to automate the generation of the assessment reports and their subsequent transmittal by diskette.

244

Effectiveness of a video-based motivational skills-building HIV risk-reduction intervention for female military personnel.  

Anecdotal evidence suggests that the HIV/AIDS prevalence rates in several African armed forces are high, with gender inequality rendering female military personnel more vulnerable to the disease. The objective of this study was to replicate a successful videotape-based HIV prevention intervention among Nigerian female military personnel in an effort to establish the cross-cultural stability, feasibility and cost-effectiveness of this approach in resource-limited countries. Enlisted women (N346) were recruited from two cantonments in Southwestern Nigeria and randomly assigned to either (a) a 5-session video-based, small group, cognitive-behavioral, HIV prevention intervention, or (b) a 5-session, video-based, contact-matched, HIV education control condition. Participants provided self-report of their HIV/AIDS-related knowledge and sexual behaviors at baseline, 3 and 6 months after completing the intervention. The results indicate that the motivational skills-building intervention did not improve participants' knowledge of HIV/AIDS any better than did the HIV education control condition at each assessment period, but it significantly increased condom use among women in this group by 53.6% at 3-month follow-up. HIV preventive behaviors among women in the motivational skills-building intervention group improved significantly, being 2 and 3 times more, compared to women in the HIV education control group at 3-month and 6-month follow-up assessments. The intervention also significantly improved behavioral intentions of participants as well as reduced alcohol use before sex by 25%, after 3 months; and number of sexual partners by 12% after 6 months. Women in the intervention group were five times more likely than women in HIV education control group to suggest that their new male partners use condom. These findings indicate that a videotape-based, HIV prevention intervention is a feasible and effective approach to HIV prevention among female military personnel from sub-Saharan Africa. PMID:21106284

245

The National Health Insurance Scheme (NHIS): a survey of knowledge and opinions of Nigerian dentists' in Lagos.  

This study was designed to assess the knowledge and perceptions of Nigerian dentists to the National Health Insurance scheme (NHIS). A cross-sectional descriptive survey was conducted amongst 250 dentists employed in private and public dental clinics in Lagos State, Nigeria. The survey instrument was a self-administered questionnaire designed to assess their knowledge and attitudes towards the scheme. Data analysis was done using the Epi-Info statistical software (version 6.04). Statistical tools used included measures of central tendency, frequency distribution and chi-square test. A total of 216 dentists (response rate of 82.4%) participated in this study. Most 132 (61.1%) of the respondents had a fair knowledge of the NHIS, while 22 (10.2%) and 62 (28.7%) had poor and good knowledge respectively. Majority (70.4%) viewed the NHIS as a good idea that will succeed if properly implemented. Most (76.6%) respondents also believed that the scheme will improve access to oral health services, affordability of services (71.4%), availability of the services (68.3%) and recognition of dentistry as a profession (62.4%). Most of the respondents (66.2%) considered oral health care as not properly positioned in the NHIS and 154 respondents (74.4%) found the current position of oral health on the NHIS unacceptable. A good number of the respondents (77.3%) would like dentistry to operate at the primary care level on the NHIS. Majority of the dentists involved in this study had some knowledge of the NHIS and were generally positively disposed towards the scheme and viewed it as a good idea. PMID:20632669

246

Management of immunization solid wastes in Kano State, Nigeria  

Inadequate management of waste generated from injection activities can have a negative impact on the community and environment. In this paper, a report on immunization wastes management in Kano State (Nigeria) is presented. Eight local governments were selected randomly and surveyed by the author. Solid wastes generated during the Expanded Programme on Immunization were characterised using two different methods: one by weighing the waste and the other by estimating the volume. Empirical data was obtained on immunization waste generation, segregation, storage, collection, transportation, and disposal; and waste management practices were assessed. The study revealed that immunization offices were accommodated in either in local government buildings, primary health centres or community health care centres. All of the stations demonstrated a high priority for segregation of the infectious wastes. It can be deduced from the data obtained that infectious waste ranged from 67.6% to 76.7% with an average of 70.1% by weight, and 36.0% to 46.1% with an average of 40.1% by volume. Non-infectious waste generated ranged from 23.3% to 32.5% with an average of 29.9% by weight and 53.9% to 64.0% with an average of 59.9% by volume. Out of non-infectious waste (NIFW) and infectious waste (IFW), 66.3% and 62.4% by weight were combustible and 33.7% and 37.6% were non-combustible respectively. An assessment of the treatment revealed that open pit burning and burial and small scale incineration were the common methods of disposal for immunization waste, and some immunization centres employed the services of the state or local government owned solid waste disposal board for final collection and disposal of their immunization waste at government approved sites.

247

HSE (CASHES) management in Niger Delta seismic operations  

3-D seismic acquisition surveys in the Niger Delta of Nigeria, are carried out under extremely arduous field conditions due to difficult terrain, dense vegetation, semi-manual mode of operation, wildlife and volatile communities. The vegetation is a combination of evergreen tropical rain forest in the land areas and mangrove in the swamp areas. Some parts of the delta are prone to high seasonal flooding. Seismic lines are laid out by manual cutting of brush using machetes and shot holes drilled semi-manually with pumps. In order to effectively carry out the operations with due regard to the people and environment, a Community Affairs, Safety, Health, Environment and Security (CASHES) Polio and management System which ensures that a hazards are identified, assessed. controlled, with an effective loop feedback mechanism was introduced and implemented. CASHES critical activities are community relations, field security, explosives handling, water transport/journey management, river crossings. weather, shallow gas blow-out, waste management, seasonal flooding and floating-seaweed (water hyacinth)/timber logs. Environmental Impact Assessment (EIA) studies arc essential at the initial planning stages. About 41 Hazard Registers and 177 Activity Specification Sheets are developed in a typical survey. About 85% of the labor workforce are recruited from the host communities to promote cordial relations. Extensive training is carried out to raise the standards of the new recruits. The implementation of the management system is cascaded down using simplified documentation (procedures, work tasks, checklists etc.) adapted to local conditions. Integrated CASHES audits (Premob, Minor, Major. Follow up) arc conducted to check the efficiency of the system with documents getting reviewed regularly to keep the system alive and capable of handling changes. With these in place, high potential incidents are reduced/eliminated.

248

Evaluation of the Effectiveness of an Initiative to Develop Leadership among Women in Africa: A Case Study  

This qualitative case study assesses the impact of a three-year Hilton Foundation-supported, Sisters Leadership Development Initiative (SLDI) in five African nations. The goal was to evaluate the SLDI program for increasing leadership capacities of 340 women in Kenya, Uganda, Tanzania, Ghana and Nigeria. The purpose of this study was to determine the program effectiveness, by observing the changes it effected in trainees and their communities. Another purpose was to assess the pedagogical practices used by both international (USA) and local (African) instructors to deliver instruction that directly applied to the trainees' workplaces. Also, the study evaluated the sustainability strategies in place to support trainee projects and future leadership programs. The design of evaluation is drawn from the theoretical perspectives elucidated by transformational leadership theory (Bass, 1985), diffusion of innovation theory (Rogers, 2003) and "culture software of the mind" (Hofstede & Hofstede, 2005). The methodology consisted on-site, data collection in Africa through in-depth interviews, site-visits observations, field notes, program document analysis, and informal conversations with subjects. The sample consisted of 45 interviewees, including 32 trainees drawn from the five sub-Saharan countries, ten instructors--four from East Africa, three from West Africa and the United States respectively, and three regional administrators. Results indicate that the program goals were attained, significant impact was evident in the trainees' adaptation of new leadership styles and models in their workplaces, innovative projects they implemented and measurable economic benefits realized Utilizing local and international instructors enhanced instruction by affording intercultural cross-fertilization. This study illustrates how the design of leadership programs can confirm the creation of innovative practice for effective organizational management in the developing nations. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.

249

Diffuse malignant peritoneal mesothelioma: Failure analysis following cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC).  

Improved survival has been reported for diffuse malignant peritoneal mesothelioma (DMPM) treated by cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC). The issue of treatment failure has never been extensively addressed. The present study assessed the failure pattern, management, and outcome of progressive DMPM following comprehensive treatment. Clinical data on 70 patients with DMPM undergoing cytoreduction and HIPEC were prospectively collected; after a median follow-up of 43 months, disease progression occurred in 38 patients. Progressive disease distribution in 13 abdominopelvic regions was analyzed. In 28 patients undergoing adequate cytoreduction (residual tumor < or =2.5 mm), clinicopathological factors correlating to disease progression in each region were investigated. Median time to progression was 9 months [95% confidence interval (CI) 1.6-35.9]. Median survival from progression was 8 months (95% CI 4-16.2). The failure pattern was categorized as peritoneal progression (n = 31), liver metastases (n = 1), abdominal lymph-node involvement (n = 2), pleural seeding (n = 4). Small bowel was the single site most commonly involved (n = 27). Residual tumor < or =2.5 mm (versus no visible) was the only independent risk factor for disease progression in epigastric region (P = 0.047), upper ileum (P = 0.029), upper jejunum (P = 0.034), and lower jejunum (P = 0.002). Progressive disease was treated with second HIPEC in 3 patients, debulking in 4, systemic chemotherapy in 16, and supportive care in 15. At multivariate analysis, time to progression <9 months (P = 0.009), poor performance status (P = 0.005), and supportive care (P = 0.003) correlated to reduced survival from progression. We conclude that minimal residual disease, compared with macroscopically complete cytoreduction, correlated to failure in critical anatomical areas, suggesting the need for maximal cytoreductive surgical efforts. In selected patients, aggressive management of progressive disease seems worthwhile. PMID:19082859

250

ENHANCED COAL BED METHANE PRODUCTION AND SEQUESTRATION OF CO2 IN UNMINEABLE COAL SEAMS  

This is the first Technical Progress report for the subject agreement. During the first six months of the project, progress was made in arranging participation by other CONSOL departments, identifying a prospective site, developing an environmental assessment report, and securing land and coal rights. In addition, correspondences were drafted in response to NETL inquiries. These aspects of the project are discussed in detail in this report.

251

National Acid Precipitation Assessment Program. Annual report 1983, to the President and Congress  

The goal of the National Acid Precipitation Assessment Program is to develop and progressively improve on an objective and comprehensive information base for use by decisionmakers. This statutory Annual Report to the President and Congress outlines the specific accomplishments of the National Program during the last year (FY 1983), summarizes the current state of scientific knowledge for decisionmakers, and describes the outlook for continued progress by the federally sponsored research effort on acid deposition.

252

Serial intravascular ultrasound assessment of changes in coronary atherosclerotic plaque dimensions and composition: an update  

This manuscript reviews the use of serial intravascular ultrasound (IVUS) examination of coronary atherosclerosis in recent observational studies and randomized trials that revealed the effects of cholesterol-lowering and lipid-modifying therapies and offered novel insight into plaque progression and regression. We discuss the value of plaque progression-regression as complementary imaging endpoint and potential surrogate marker of cardiovascular event risk. In addition, the progress in serial assessment of coronary plaque composition and plaque vulnerability by radiofrequency-based analyses is reviewed. Finally, we report on the evaluation of true vessel remodelling in recent serial IVUS trials and discuss the future perspective of serial invasive imaging of coronary atherosclerosis.

253

Bevacizumab continuation beyond initial bevacizumab progression among recurrent glioblastoma patients  

Background:Bevacizumab improves outcome for most recurrent glioblastoma patients, but the duration of benefit is limited and survival after initial bevacizumab progression is poor. We evaluated bevacizumab continuation beyond initial progression among recurrent glioblastoma patients as it is a common, yet unsupported practice in some countries.Methods:We analysed outcome among all patients (n=99) who received subsequent therapy after progression on one of five consecutive, single-arm, phase II clinical trials evaluating bevacizumab regimens for recurrent glioblastoma. Of note, the five trials contained similar eligibility, treatment and assessment criteria, and achieved comparable outcome.Results:The median overall survival (OS) and OS at 6 months for patients who continued bevacizumab the...

254

Bevacizumab Combined With Chemotherapy in the Second-Line Treatment of Metastatic Colorectal Cancer: Results from the Phase II BEVACOLOR Study  

Background This prospective phase II study assessed the efficacy and safety of bevacizumab plus chemotherapy regimens commonly used in the second-line treatment of metastatic colorectal cancer (mCRC). Methods Patients with mCRC who progressed or relapsed after first-line oxaliplatin-based or irinotecan-based treatment received bevacizumab 2.5 mg/kg/week plus chemotherapy until disease progression. The primary endpoint was disease-control rate (DCR). Secondary endpoints included progression-free survival (PFS), overall survival (OS), objective response rate (ORR), and safety. Results Fifty-three patients (66% men; median age, 62 years old) received second-line bevacizumab plus folinic acid, fluorouracil, and irinotecan (FOLFIRI; 57%), folinic acid, fluorouracil, oxaliplatin (FOLFOX; 26%), i...

255

Enzyme linked immunosorbent assay for the diagnosis of cerebral cysticercosis in Reunion island: comparison with computerized tomography scan  

An immunoenzymologic (Elisa) serodiagnosis of cysticercosis is evaluated in 75 encephalic cysticercotic patients whose diagnosis of the disease and its progression is assessed by tomodensitometry. A Taenia solium antigen is used. Only Ig G are investigated. The sensibility of serodiagnosis is 85 % and specificity 87 % when there is a progression of the disease; no difference is noticed in the patients without any progression of the disease and in control normal subjects. This serodiagnosis of cysticercosis appears of value for the evaluation of the activity of the disease.

256

Measurement of radioelement contents of rocks of Ugep, S. E. Nigeria, by gamma-ray spectrometric and instrumental neutron activation analysis techniques  

A combination of gamma-ray spectrometry and instrumental neutron activation analysis is adopted in the quantitative evaluation of the three major radioelements (U, Th and K) concentrations in some rock samples collected at previously delineated radiometric anomalies (Geological Survey of Nigeria, 1976), in the Ugep area of the Lower Benue Region of Nigeria. A preferential enrichment of Th to U and K is observed in most samples analysed, with U/Th ratios ranging from 0.11 to 0.25. K contents are fairly normal in some samples analysed, with Th (ppm)/K (%) ratios ranging from 2 to 5. Anomalous Th/K ratios, Th (ppm)/K (%) ratios ranging from 2 to 5 up to 16, were obtained for samples from those areas identified in the airborne survey maps as ''Th-anomaly zones'' (Geological Survey of Nigeria, 1976). (Author).

257

Can non-wood forest products be used in promoting household food security?: Evidence from savannah and rain forest regions of Southern Nigeria  

Despite the importance of non-wood forest products (NWFPs) in household consumption especially in Nigeria, where 47million people were unable to meet the 2,900kcal food requirement in 2004, they have hitherto been neglected by planners policy makers and natural resource managers. To encourage its recognition and conservation, sustain benefits, this study analyses the place of plant species of NWFPs in household food security in Southern Nigeria. Data were collected from 400 households in Cross River and Enugu States of Southern Nigeria. Descriptive statistics and probit regression were used in data analysis. The study revealed that Bush mango (Irvingia gabonensis and I. wombolu), afang (Gnetum africanum), oil bean (Pentaclatra macrophyla), African mesquite (Prosopis africana) and bread fru...

258

West African crude production diversifies  

Nigeria, with its seven crude-oil export streams, dominated West African production and accounted for over 70% of the depressed 1.8 million b/d output from the region last year. However, during the 1970s a flurry of new producing fields, primarily off the African coast, diversified production among a number of countries and touched off a wave of oil activity. The Journal takes a close look at the quality of West African oil in this installment of assays on world export crudes. This issue covers, in alphabetical order, Bonny Light (Nigeria) to Espoir (Ivory Coast). A following issue will wrap up West Africa by presenting assays on crudes from Forcados Blend (Nigeria) to Zaire Crude (Zaire).

259

Niger Delta Youth Restiveness and Socio-Economic Development of Nigeria  

This paper examines youth restiveness in the Niger Delta region of Nigeria, and the challenges it posed to Nigeria democracy and foreign investment. Non-parametric statistical and content analyses were essentially used as tools of analysis. The results showed that dissatisfaction of the people of Niger Delta especially the youths on the level of attention given to the development of their region and the damages to their ecology by oil spillage are the major causes of the alarming youth restiveness. Surprisingly, the Niger Delta region constitutes about 80% to the revenue of Nigeria. It is against this backdrop that the paper suggests an immediate review of the current revenue sharing formula. The new formula should be made to address poverty, and neglect of the Niger Delta region. Oil companies operating in the region should pay a greater percentage of their royalty directly to the host communities in the Niger Delta region. (Contains 7 tables.)

260

Characteristics of global architectural firms  

Purpose - The aim of this paper is to investigate the factors which discriminate between local and global architectural firms in Nigeria. The rationale was to examine how the globalization process differs in Nigeria and contribute to the discourse on globalization. Design/methodology/approach - The research is quantitative, using discriminant analysis to differentiate the global architectural firms from the local ones. The study used a random sample of 92 architectural firms in Nigeria, examining various characteristics of the firms through a questionnaire. Findings - There was a strong distinction between global and local firms. Compared to the local architectural firms, the global firms were larger, and mostly run by sole principals who were more experienced. The internet was used more t...

 
 
 
 
261

Residents' perception of the quality of public housing in urban areas in Ogun State, Nigeria  

Purpose - The general aim of this research is to investigate residents' perception of the quality of public housing and factors influencing this in Ogun State Southwest Nigeria. This is in view of a paucity of published works on this subject matter and the need to upgrade the quality of public housing in urban areas in Nigeria. Design/methodology/approach - Data for the study were collected through a cross sectional survey of proportionately selected 517 household heads in newly constructed public housing estates, and 90 staff members of four key public housing agencies in urban areas of Ogun State, Nigeria. Structured questionnaires were used in the collection of primary data. Descriptive statistics and categorical regression analysis were used in data analysis. Findings - The results sho...

262

Conceptualizing Curriculum for the Future in a Changing Society. Studies in Educational Administration Number 46.  

This paper is a proposal for a curriculum of the future in the changing society of Nigeria. A deliberate effort is made to prescribe and predict elements essential for a responsive and dynamic futuristic curriculum, without necessarily describing the specific details of such a curriculum. Although predicting the shape of education in the future is risky, it is contended that unless modern man adapts his thinking and his behavior to the realities of the present and plans for the future, he is most likely to repeat endlessly the mistakes of the past. Most of the ideas suggested for the future of the curriculum in Nigeria are accordingly offered as possible guides for Nigeria's new system of education. Topics covered include the concept of responsiveness to technological and social developments, the concept of balance in the curriculum of the future, teachers in the curriculum of the future, creativity, and decentralization. A five-item bibliography is included. (Author/TE)

263

Food potentials of some unconventional oilseeds grown in Nigeria--a brief review.  

A brief review of literature on kernels of Citrullus and Cucumeropsis ('egusi' melon) species, Telfairia occidentalis (fluted pumpkin), Lagenaria (gourd) species of all of Cucurbitaceae family and other oilseeds such as Pentaclethra macrophylla (African oil bean), Parkia spp. (African locust bean) both of Mimosaceae family and Butyrospermum paradoxum (shea butter) of Sapotaceae family which are grown and widely used as food in Nigeria is presented. The kernels of species of Cucurbitaceae form the bulk of unconventional oilseeds used for food in Nigeria. The nutritional value of some of the kernels and the physicochemical properties and storage stability of the oils obtained from them are discussed. The various consumable forms in which they exist are also described. The problems and prospects of these neglected oilseeds in Nigeria are highlighted. PMID:8506236

264

Three hydroxylated lupeol-based triterpenoid esters isolated from the Eastern Nigeria mistletoe parasitic on Kola acuminata.  

Column fractionation and purification of an n-hexane fraction led to the isolation of three lupeol-based triterpenoid esters from the leaves of the Eastern Nigeria mistletoe, Loranthus micranthus Linn parasitic on a local kola nut tree, Kola acuminata. These three compounds were adequately characterised using a combination of UV/visible, IR, NMR ((13)C-NMR and (1)H-NMR), DEPT, MS and two-dimensional correlation (H-H COSY, Hetero-nuclear Single Quantum Correlation (HSQC), HMBC, NOE and NOESY) studies as 7?,15?-dihydroxyl-lup-20(29)-ene-3?-esters of palmitic (I), stearic (II) and eicosanoic acids (III). The characterisation of other isolated compounds is ongoing. Remarkably, this is the first report of the existence of fatty acid esters of an unusual 7?,15?-dihydroxylated lupeol in the Eastern Nigeria mistletoe. These isolated compounds might contribute in part to the numerous established bio-activities of the Eastern Nigeria mistletoes. PMID:22007932

265

Environmental health, development and economic empowerment of rural women in Nigeria  

Sustainable development is a process that has social, cultural, economic and ecological dimensions. The necessity of improving the quality of life of rural women in terms of socio-economic aspects in developing countries like Nigeria is the aim of this study. The study was carried out in four villages of Tonkere district (Okeake, Abagboro, Elefon and Akiri), situated on expansive university land at Ile-Ife and typical of rural settings in Nigeria. Data were generated from group meetings, local government and individual interviews and surveys. In rural Nigeria, women?s essential contributions to overall environmental health, development and economy are negatively influenced by domestic tasks such as gathering of fuel woods and biomass for cooking. In reality, wood burning, kerosene stoves, ...

266

Ergonomic evaluation and energy requirements of bread-baking operations in south western Nigeria  

Purpose - In Nigeria, local fabricators of agro-processing equipment have designed and manufactured various improvised versions of imported bread-baking machines without due ergonomic considerations. Also, most of the processes of bread baking in Nigeria largely involve manual materials handling, which continues to represent a major loss source in the work place. The manual operations besides being uncomfortable are characterized by low output and unhygienic products. A study was therefore conducted in three southwestern states of Nigeria with the purpose of evaluating the energy requirements and man-machine relationships in bread-baking operations. Design/methodology/approach - The study, which lasted over one year, involved the use of three fuel sources namely, firewood, electricity and ...

267

Assessment of infection control practices in maternity units in Southern Nigeria  

Objective. Puerperal sepsis accounts for 12% of maternal deaths in Nigeria. To date, little is known about the background hospital factors that predispose pregnant women to puerperal infection that leads to mortality. The objective of this study was to investigate the nature and pattern of existing policies and practices relating to infection control in maternity care centres in Edo state, South-South Nigeria. Design. Cross-sectional study consisting of in-depth interviews with service providers, observation of clinical practices and examination of medical records. Setting. Public and private health-care facilities in eight local government areas (LGAs) selected from the three senatorial districts of Edo State, Nigeria. Participants. Health providers from 63 primary, secondary and t...

268

Virulent Newcastle disease virus in Nigeria: identification of a new clade of sub-lineage 5f from livebird markets  

Newcastle disease (ND), caused by Avian Paramyxovirus Type 1, is a highly contagious and devastating viral disease of poultry of worldwide distribution with an enormous economic impact. Although ND is reported to be endemic in Nigeria, little information exists on the molecular epidemiology and the lineage distribution of the Newcastle disease viruses (NDVs) in the country, especially in the live bird markets (LBMs). Recent studies reported the identification of three unique sub-lineages. namely; 5f, 5g and 5h in West Africa, and sub-lineages 5f and 5g in particular in non-commercial farms in Nigeria. In this study, 33 NDV isolates, which included NDVs recovered from LBMs in Nigeria, during active surveillance from 2007 to 2008 and viruses recovered from outbreaks in backyard and commercia...

269

Challenges facing women entrepreneurs in Nigeria  

Purpose - This study seeks to examine the business and social profiles of 67 women entrepreneurs in three regions of Nigeria in order to identify patterns of entrepreneurship and social and economic challenges facing women business owners in Nigeria. The study aims to support and encourage sustainable small-scale economic development activities by Nigerian women and determine ways to integrate these small businesses into existing urban economic development projects and strategies for poverty alleviation, expand understanding of the business and social profiles of women entrepreneurs in Nigeria, examine the contextual influences on their work, raise the level of awareness of women entrepreneurs amongst all economically active agents and researchers, influence social and economic policy addr...

270

Solid Waste Management in Nigeria: Problems and Issues.  

/ This paper is a presentation of the problems of solid waste management in Nigeria and certain important issues that must be addressed in order to achieve success. At the core of the problems of solid waste management are the absence of adequate policies, enabling legislation, and an environmentally stimulated and enlightened public. Government policies on the environment are piecemeal where they exist and are poorly implemented. Public enlightenment programs lacked the needed coverage, intensity, and continuity to correct the apathetic public attitude towards the environment. Up to now the activities of the state environmental agencies have been hampered by poor funding, inadequate facilities and human resources, inappropriate technology, and an inequitable taxation system. Successful solid waste management in Nigeria will require a holistic program that will integrate all the technical, economic, social, cultural, and psychological factors that are often ignored in solid waste programs.KEY WORDS: Solid waste; Management; Problems; Solutions; Nigeria PMID:9732514

271

Towards achieving the United Nations? Millennium Development Goals: The imperative of reforming water pollution control and waste management laws in Nigeria  

Nigeria is among the group of developing countries that have adopted the Millennium Development Goals (MDGs) blueprint as a veritable vehicle for poverty eradication, economic growth and sustainable development. However, the pollution of its surface water from discharges from domestic, industrial and agricultural waste degrading the quality of fresh water available to human needs and poor environmental sanitation cast serious doubt on Nigeria?s ability to meet the United Nations? (UN) MDGs as most of the citizen still obtain water for domestic use from natural sources. This paper examines the efficacy of the legal framework that protects water from pollution. It concludes these laws are inadequate to meet the contemporary challenges of managing water that is an essential component to meet ...

272

Review of the radioactive waste management system in Nigeria.  

The management of radioactive waste in Nigeria from early 1960 to date is reviewed. As in many developing countries, waste management in Nigeria has been shown to be ineffective. The factors that are responsible for this ineffectiveness are identified and discussed. The steps being taken by and the opportunities available to the newly established Nigerian Nuclear Regulatory Authority towards addressing this problem of ineffectiveness are discussed. The efforts of this newly set up body towards managing the resultant radioactive wastes that will be generated during the use of a reactor and an accelerator that will soon be commissioned in Nigeria are also mentioned. Likely ways of further addressing the problems militating against waste management in developing countries are suggested. PMID:12729418

273

Review of the radioactive waste management system in Nigeria  

The management of radioactive waste in Nigeria from early 1960 to date is reviewed. As in many developing countries, waste management in Nigeria has been shown to be ineffective. The factors that are responsible for this ineffectiveness are identified and discussed. The steps being taken by and the opportunities available to the newly established Nigerian Nuclear Regulatory Authority towards addressing this problem of ineffectiveness are discussed. The efforts of this newly set up body towards managing the resultant radioactive wastes that will be generated during the use of a reactor and an accelerator that will soon be commissioned in Nigeria are also mentioned. Likely ways of further addressing the problems militating against waste management in developing countries are suggested. (review)

274

Biofuels adoption in Nigeria: A preliminary review of feedstock and fuel production potentials  

Purpose - The purpose of this paper is to make a preliminary analysis of the potentials for the adoption of biofuels in Nigeria. This initial analysis aims to capture some of the possibilities in the adoption of biofuel and the promotion of the cultivation of energy crops and processing of biofuels in Nigeria. Taking a step towards biofuel adoption is crucial for Nigeria to remain an important player in the world energy market, as there is a shift in global fossil fuel consumption. Design/methodology/approach - The study adopted a desk review of existing literatures on global biofuels production potentials. A synthesis of data from the Food and Agriculture Organization (FAO) secondary database on major energy crops production was also conducted, while the GIS map was generated from GIS dat...

275

Audit of Management of Gallbladder Cancer in a Nigerian Tertiary Health Facility  

Background Gallbladder cancer is a rare malignancy with a variable incidence worldwide. It ranks number eight among all gastrointestinal cancer seen in Nigeria. It is associated with high mortality and morbidity because it is usually diagnosed very late. Adequate surgical resection is the only modality with hope of cure. This requires advanced surgical skills which is quite rare in most developing countries like Nigeria. In this current work, we audit the management and outcome of gallbladder cancer in our hospital, highlighting peculiarity associated with our setting. Patients and Method Consecutive patients managed as cases of gallbladder cancer at Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria between January 1990 and December 2010 were studied retrospectively. ...

276

The Nigeria Experience  

This article featuring Nigeria constitutes one of five articles in a collection of essays on local capacity-building in research ethics by graduates from the University of Toronto?s Joint Centre for Bioethics MHSc in Bioethics, International Stream programme funded by the Fogarty International Center for Advanced Study in the Health Sciences (FIC). The first National Health Research Ethics Committee was inaugurated in 2006. Since then, more institutional health research ethics committees continue to be formed. However, research ethics challenges in Nigeria are systemic and require a systems approach to address them effectively. Nigeria requires capacity-building for authentic acculturation of health systems as well as for health research, education, and advocacy within the research communi...

277

Advanced direct liquefaction concepts for PETC generic units. Quarterly technical progress report, April 1993--June 1993  

Section 1 contains a report of the progress by the University of Kentucky Center for Applied Energy Research on the following tasks: laboratory support (liquefaction in dewaxed and hydrotreated dewaxed solvent); CO pretreatment (effect of process variables on CO pretreatment, CO-pretreated product characterization, and liquefaction results); and iron based dispersed catalysts (production, characterization and testing of sulfated hematites and reaction model development). Section 2 contains a progress report by CONSOL, Inc. on the following tasks: laboratory support; pretreatment work on dewaxing; pretreatment work on agglomeration; and economic evaluation. Progress by Sandia National Laboratories is reported in Section 3 on the following: laboratory support (TGA methods) and solvent pretreatment (coker tar hydrogenation and coal liquefaction results). Section 4 gives a preliminary technical assessment by LDP Associates on the following: baseline economic assessment; assessment of improved coal conversion; and fluid coking.

278

Irrigating the famished fields: The impact of labour-led struggle on policy and action in Nigeria (1999-2007)  

Between 1999 and 2007, a broad-based labour-led movement which focused most of its energies on its struggle against unpopular fuel price hikes in Nigeria was able to exert considerable, though limited, influence on an Obasanjo-led executive arm of government that was at best quasidemocratic in its orientation. This article argues that, despite the very important roles played by other factors (notably the presence of more democratic space in Nigeria post-1999), the movement's adoption of a mass social movement approach facilitated its ability to exert such influence.

279

Socioeconomic determinants of poverty among urban households in South-West Nigeria  

Purpose - The role of household socio-economic factors towards achieving enduring poverty interventions especially among urban households of Nigeria cannot be overemphasized. Household socio-economic factors, among others, have been identified by development practitioners in developing countries as variables which can easily be manipulated through policy levers to improve welfare of the poor. The purpose of this paper is to examine poverty situations among urban households in Ekiti State, Nigeria with emphasis on household socioeconomic characteristics and their associated influence on poverty. Design/methodology/approach - A multistage sampling approach was used to select 80 households who were interviewed using a well structured questionnaire. Data collected were analyzed through Poverty...

280

Niger Delta basin oil and gas prospects evaluated  

This paper reports that an ambitious project to map African oil and gas prospects has produced its first findings in a report on the Niger Delta basin. In Nigeria, 73% of discoveries are smaller than 50 million bbl, with a 42% success rate for wildcats. There are 'out of round prospects off Nigeria, too, with a number of companies currently in discussions. Petroconsultants the there are further opportunities for exploration in the Northern Onshore Fringe Belt, which has an estimated potential of 500 million bbl of reserves. Three OPLs are open.

 
 
 
 
281

Prevalence and correlates of elder abuse among older women in rural and urban communities in South Western Nigeria.  

Elderly women face the same health, economic, and social issues that all elderly people face, but often encounter more challenges compared with men and are more prone to abuse. Elder abuse has hitherto been uncharacterized among women in South Western Nigeria. A cross-sectional survey was conducted to describe the prevalence, patterns, and factors associated with elder abuse among elderly women in Nigeria. The abuse of elderly women is quite prevalent in the two communities studied, especially physical abuse. Positive predictors of elder abuse were urban dwelling, financial dependency, and a high level of educational attainment. Appropriate interventions should be targeted toward reducing the occurrence. PMID:22946597

282

Review of West Africa. Elephant hunting is starting again. More numerous and various operators. Angola, an expansion with large fields. Congo, after Nkossa. Girassol: the selected companies. A controversial project, the Chad-Cameroon pipeline. Gabon, no discovery since 8 years. Nigeria, every man for himself. Ivory Coast, a more attractive legislation. The African legislation is evolving. Bouygues Offshore is on tracks for deep sea. The African contracts for ETPM; Dossier Afrique de l'Ouest. La chasse a l'elephant reprend de plus belle. Des acteurs plus nombreux et plus divers. Angola - une expansion par grands champs. Congo - l'apres Nkossa. Girassol: les entreprises retenues. Un projet controverse - le pipeline Tchad-Cameroun. Gabon - pas de decouvertes depuis huit ans. Nigeria - chacun pour soi. Cote d'Ivoire - une legislation plus attractive. La legislation petroliere africaine evolue. Bouygues Offshore en piste pour la mer profonde. Les contrats africains d'ETPM  

A review of the petroleum and gas reserves, production and exploration situation in the various West African countries is presented with maps and statistics. It is shown that numerous projects are developed, especially in offshore Guinea Gulf, with small and large petroleum companies rushing to Nigeria, Angola, Gabon, etc. The various projects and companies selected for Angola, Congo, Gabon and Nigeria oil fields are discussed, together with the prospectives for Ivory Coast and the evolution of legislation related to petroleum in Africa. Bouygues Offshore's strategy in the Guinea Gulf is exposed and the african contracts for the platform and pipeline specialist ETPM are detailed.

283

Changes in knowledge and attitudes among junior secondary students exposed to the family life and HIV education curriculum in Lagos State, Nigeria.  

To address the needs of young people in Lagos State, Nigeria, for information about family life and HIV, the Lagos State Ministry of Education, in collaboration with Action Health Incorporated, began to offer the Family Life and HIV Education Curriculum in government junior secondary schools in 2003. Knowledge and attitudes were measured in a sample of 1,366 students in Lagos State, Nigeria, in November 2004, at the beginning of the school year, and again in July 2005 after receiving a year of the Family Life and HIV Education Curriculum. Students exposed to the curriculum significantly increased knowledge of sexuality and HIV, support for abstinence, and gender role equality. PMID:20690260

284

Sexual and reproductive health communication between mothers and their adolescent daughters in northern Nigeria.  

We employed structured interviews and focus groups to investigate reproductive health (RH) communication practices among 184 mother-daughter pairs in Ungogo, northern Nigeria. Transcripts were analyzed using the grounded theory approach. A total of 136 mothers reported discussing RH issues with their daughters. The majority of daughters acquired RH education from their mothers. Parents were more likely to discuss marriage, menstruation, courtship, premarital sex, and sexually transmitted infections (STIs) than other sex education topics. Mothers in northern Nigeria need to be empowered with knowledge and skills to improve the scope and quality of home-based RH education. PMID:22242654

285

Epidemiology of dermatophytoses in a rural community in Eastern Nigeria and review of literature from Africa.  

A total of 4,287 primary school children, comprising 1,740 males and 2,547 females in Arochukwu local government area of Abia state Nigeria were examined for clinical signs of dermatophytoses. About 873 (20.4%), consisting of 505 males and 368 females had lesions consistent with dermatophytoses. The disease was more prevalent in males (29%) than females (14.4%) in a ratio of approximately 2:1 (P Microsporum audouinii (6.4%), Microsporum gypseum (6.0%), Trichophyton rubrum (5.5%) and Microsporum ferrugineum (7.3%), which was isolated for the first time in Nigeria. PMID:17657581

286

Forestry residues, wood wastes and fibreboard production and possible uses in Nigeria  

Nigeria has tremendous agricultural potential particularly in forest resources. Whilst some efforts have been devoted towards tapping the forest resources, substantial evidence shows that forest residues and wood wastes in, for example, sawmills, have not been properly made use of. However, forest products such as fibreboard are being heavily imported in the wake of dwindling foreign exchange earnings. This paper projects the supply of forestry residues and wood wastes and presents ways in which they can be economically used to produce fibreboard in Nigeria. The use of such agricultural waste is called for in other less developed countries demanding an adoption of appropriate technology. 3 references.

287

Incidence of Fusarium moniliforme Sheld. in Zea mays L. in the rainforest zone of Nigeria.  

45 seed samples from 7 states of the rainforest zone of Nigeria (Ogun, Ondo, Oyo, Bendel, Anambra, Imo, and Cross River) were screened for phytopathogen incidence. Whereas Drechslera maydis was found in 30 and Cephalosporium maydis in 79% of the samples were infected by Fusarium moniliforme, with 70% of the samples showing heavy infection. In view of the widespread nature of this economically important fungus on maize in the main cultivation area of Nigeria, the necessity for routine laboratory seed health tests is clearly indicated. PMID:550860

288

Plasmid-mediated quinolone resistance and β-lactamases in Escherichia coli from healthy animals from Nigeria  

Objectives The animal reservoir of plasmid-mediated quinolone resistance (PMQR) and ?-lactamases is still controversial and little information is available on the prevalence of these resistance determinants in developing countries. The aim of this study was to identify and characterize PMQR and ?-lactamases in a collection of commensal ampicillin-resistant Escherichia coli isolated from healthy chickens and pigs at slaughter, collected in November–December 2006, in Ibadan, Nigeria. Methods One hundred and sixty-two ampicillin-resistant E. coli were obtained from healthy chickens and pigs at slaughter in Ibadan, Nigeria. Strains were tested for antimicrobial susceptibility by disc diffusion assay. MICs of ciprofloxacin were determined by Etest. Resistance genes were scr...

289

Evaluation of image-based modeling and laser scanning accuracy for emerging automated performance monitoring techniques  

Accurate and rapid assessment of the as-built status on any construction site provides the opportunity to understand the current performance of a project easily and quickly. Rapid project assessment further identifies discrepancies between the as-built and as-planned progress, and facilitates decision making on the necessary remedial actions. Currently, manual visual observations and surveying are the most dominant data capturing techniques but they are time-consuming, error-prone, and infrequent, making quick and reliable decision-making difficult. Therefore, research on new approaches that allow automatic recognition of as-built performance and visualization of construction progress is essential. This paper presents and compares two methods for obtaining point cloud models for detection ...

290

Assessing the potency of respiratory allergens: Uncertainties and challenges  

In contrast to skin sensitisation, there are no accepted tests for the identification of chemicals or proteins with the potential to cause sensitisation of the respiratory tract. Although progress has been made, the assessment of respiratory sensitisation potential remains associated with significant challenges and uncertainties. Nevertheless, there is interest in determining whether it is possible to assess the relative potency of respiratory sensitisers. The second Adaptation to Technical Progress (ATP) to the EU Classification, Labelling and Packaging (CLP) Regulation recently introduced changes to criteria for classification and labelling of chemicals and preparations, bringing it in line with the 3rd revision to the UN Globally Harmonised System of Classification and Labelling of Chem...

291

A Bayesian approach to monitoring and assessing unexploded ordnance remediation progress from munitions testing ranges  

We present a statistical methodology which aims to monitor and assess the progress of unexploded ordnance remediation. We explicitly quantify the probability that each buried sensor-identified anomaly is not a target of interest conditional on the information gleaned from anomalies which have been dug and identified. We provide a measure of confidence that the anomalies which remain onsite after remediation are not unexploded ordnance?this measure of confidence is gleaned through Monte Carlo methods. The methodology is iterative in that, at any point in the remediation process, we can assess remediation progress and compute the probability that no targets of interest remain given the available dig information.

292

Longitudinal evaluation of neuropsychiatric symptoms in Huntington's disease.  

A group of 111 patients with Huntington's disease (HD) underwent a minimum of three annual neuropsychiatric assessments, using the Problem Behaviors Assessment for Huntington's Disease (PBA-HD). Longitudinal prevalence of neuropsychiatric symptoms was notably higher than baseline prevalence, suggesting that previous studies may have underestimated the extent of this clinical problem. Moreover, apathy, irritability, and depression were each associated with distinct longitudinal profiles. Apathy progressed over time and across disease stages. Irritability also increased significantly, but only in early stages of HD. Depression did not increase significantly at any stage of disease. The neuropsychiatric syndrome of apathy appears to be intrinsic to the evolution and progression of HD. PMID:22450614

293

Cognitive foundations for science assessment design: Knowing what students know about evolution  

Abstract To improve assessments of academic achievement, test developers have been urged to use an -assessment triangle- that starts with research-based models of cognition and learning [NRC (2001) Knowing what students know: The science and design of educational assessment. Washington, DC: National Academy Press]. This approach has been successful in designing high-quality reading and math assessments, but less progress has been made for assessments in content-rich sciences such as biology. To rectify this situation, we applied the -assessment triangle- to design and evaluate new items for an instrument (ACORNS, Assessing Contextual Reasoning about Natural Selection) that had been proposed to assess students' use of natural selection to explain evolutionary change. Design and scoring of i...

294

Increasing use of artemisinin-based combination therapy for treatment of malaria infection in Nigerian hospitals/ Aumento del uso de tratamientos combinados con artemisina para el tratamiento de la infección de malaria en hospitales nigerianos  

Abstract in spanish Objetivos: Este estudio trató de describir el patrón de prescripción ambulatoria de antimaláricos en un hospital secundario y terciario, y evaluar el cumplimiento de la Guía Nacional de Tratamiento Antimalárico (ATG). Métodos: Se realizó un audit de los archivos de prescripción de antamaláricos en dos establecimientos sanitarios de un periodo de seis meses en 2008. Se utilizaron cuestionarios semi-estructurados para recoger informaciones del conocimiento de méd (more) icos y farmacéuticos de la Guía Nacional de Tratamiento Antimalárico. Resultados: Los tratamientos de combinación con artemisina (TCA) fueron los antimaláricos más prescritos. Del total de prescripciones, el 81,4% TCA, de las cuales el 56,8% eran artemeter-lumefantrina. Sin embargo, el cumplimiento de los medicamentos indicados en las guías nacionales con el DU90% fue del 38,5% en el hospital terciario y del 66,7% en el secundario. La práctica de prescripción por nombre genérico todavía no era seguida en ninguno de los hospitales. El porcentaje de profesionales sanitarios que conocía las TCA era del 88,2% de los médicos y del 85,1% de los farmacéuticos. Sin embargo, el 13,3% y el 52,2% de médicos y farmacéuticos, respectivamente, no pudo enunciar adecuadamente la lista de medicamentos especificados en la guía. La amodiaquina fue la opción más frecuentemente preferida para tratar a niños de 0-3 meses con infección de malaria, en lugar de la indicada quinina oral. Conclusión: Este estudio mostró un aumento del uso de regímenes de combinación con artemisina para tratamiento de malaria no complicada en comparación con anteriores informes de Nigeria. Este estudio también remarca la necesidad de un periódico aseguramiento de la calidad interno entre los profesionales sanitarios, monitorizando el cumplimiento y el conocimiento de las guías clínicas para asegurar la práctica basada en la evidencia. Abstract in english Objectives: This study aimed at describing the pattern of outpatient antimalarial drug prescribing in a secondary and a tertiary hospital, and to assess adherence to the National Antimalarial Treatment Guideline (ATG). Methods: An audit of antimalarial prescription files from the two health facilities for a period of six months in 2008 was conducted. Semi structured questionnaires were used to collect information from the doctors and pharmacists on their awareness and kno (more) wledge of the National Antimalarial Treatment Guideline. Results: Artemisinin-based combination therapies (ACTs) were the most prescribed antimalarials. Overall, 81.4% of the total prescriptions contained ACTs, out of which 56.8% were artemether-lumefantrine. However, adherence to the drugs indicated by national guideline within the DU90% was 38.5% for the tertiary and 66.7 % for the secondary hospital. The standard practice of prescribing with generic name was still not adhered to as evidenced in the understudied hospitals. The percentage of health care providers that were aware of the ATG was 88.2% for doctors and 85.1% for pharmacists. However, 13.3% and 52.2% of doctors and pharmacists respectively could not properly list the drugs specified in the guideline. Amodiaquine was the most commonly preferred option for managing children aged 0 - 3 months with malaria infection against the indicated oral quinine. Conclusion: This study showed an increased use of artemisinin-based combination therapy for the treatment of uncomplicated malaria compared previous reports in Nigeria. This study also highlights the need for periodic in-service quality assurance among health professionals with monitoring of adherence to and assessment of knowledge of clinical guidelines to ensure the practice of evidence based medicine.

295

Effect of statin on progression of symptomatic intracranial atherosclerosis.  

Background: Symptomatic intracranial atherosclerosis (ICAS) is a dynamic disease that frequently progresses. Statins have been shown to have anti-atherosclerotic activity. We therefore investigated whether statins could prevent progression of ICAS. Methods: This retrospective cohort study assessed 55 patients with acute ischemic stroke and symptomatic ICAS in the middle cerebral or basilar arteries as shown on magnetic resonance angiography (MRA), with follow-up MRA performed more than 1 year after the index stroke. Change in ICAS was classified as progressive, regressive, or stable. Baseline clinical characteristics and risk factor control during follow-up were assessed, and laboratory tests were performed at the time of follow-up MRA. The statin group was defined as patients regularly treated with statins for more than 75% of the follow-up period; the remaining patients were defined as the non-statin group. Results: At a median follow-up time of 21.8 months (range, 11.8-66.1 months), the statin group consisted of 26 (47.3%) patients and the non-statin group of 29 (52.7%). During follow-up, 6 (10.9%) patients progressed, 14 (25.5%) regressed, and 35 (63.6%) remained stable. Statin treatment was significantly associated with non-progression of ICAS (p=0.024). Two patients in the non-statin group had recurrent strokes. Border-zone infarcts were associated with progression of ICAS (3/6, 50%; p=0.007), whereas risk factors and inflammatory biomarkers were not related to progression. Conclusions: Treatment with statins may prevent progression of symptomatic ICAS. Prospective randomized controlled trials are required to confirm that statins protect against such progression. PMID:23041401

296

Geochemical and Mineralogical Significance of Trace Metals in Benue Trough Coal, Nigeria  

In the present study, sub-bituminous coals from Ribadu, Okaba, Okpara, Orukpa, Ogboyoga and Lignite from Asagba, all from Benue Trough, Nigeria were analyzed by energy dispersive x-ray fluorescence spectrophotometer (EDXRF). Different concentrations of trace metals present in the coal samples were recorded and subsequently used to determine the origin, organic matter input, maturity and mineralogical importance of the coals. There is closeness between Chromium (Cr) and Nickel (Ni) content as well as V/Ni ratio for the coals suggesting that the organic matter is derived from terrestrial/marine and are of low maturity. Also, the low V/V+Ni ratios for all the coals suggest that they are deposited under oxic condition, which is in agreement with earlier work done on these coals by other workers. Therefore, these ratios compliment with other geochemical parameters can be a useful tool in geochemical studies. Preliminary assessments of the mineral contents of the coal samples reveal that there is possible occurrence of iron bearing minerals like pyrite, siderite and ankerite and titanium rich minerals; ilmenite and rutile in the studied area. This is due to high abundance of iron (Fe) and titanium (Ti) in the samples. Also the level of some metals such as nickel, iron, titanium and copper in these samples indicate that the ash residue of these coals after burning could be a very good source of the metals. However, the presence of some trace elements like copper (Cu) and nickel (Ni) that causes corrosion of the turbines and also poison catalyst, in the coals, necessitate incorporation of the removal procedures of these metals before refining stage.

297

Prevalence of mange among West African Dwarf sheep and goats and associated haematological and biochemical parameters.  

This study was carried out to assess the prevalence of mange in sheep and goats in five local government areas (LGAs) of Ogun State in South Western Nigeria. A total of 4,973 sheep and 7,902 goats of West African Dwarf breeds were sampled of which only 4 (0.08%) of sheep and 42 (0.53%) of goats were confirmed positive for mange infestation. In all the LGAs sampled, Odeda LGA had the highest concentration of sheep (39%) and goats (51%) while Abeokuta South had the least percentage of sheep (1%) and goats (1%). All the mange-infested cases in sheep were recorded in just one LGA (Ewekoro) which constituted 0.24% of the population within the location. For goats, three out of five LGAs namely: Obafemi Owode, Ewekoro and Abeokuta North had prevalence of 1.46%, 0.53% and 0.72% respectively. There was no significant (P > 0.05) difference between non-infested and infested animals in terms of packed cell volume (31.79 ± 0.87% vs. 31.41 ± 1.13%), haemoglobin (10.51 ± 0.21 g/100 ml vs. 10.28 ± 0.37 g/100 ml) and red blood cells (8.71 ± 0.29 × 10(12)/l vs. 9.40 ± 0.37 × 10(12)/l). The infested group however showed significantly (P mange mite infestation varied with location and was generally low or absent in some of the LGAs considered. Goats were particularly more susceptible to mange infestation than sheep. More concerted effort is needed to control mange in order to avoid spread since it is a contagious disease. PMID:22246540

298

Quality of hemodialysis water in a resource-poor country: The Nigerian example.  

Hemodialysis (HD) patients are exposed to large volumes of water, separated from patients' blood by semipermeable membrane of dialyzers. Chemical contaminants in poorly treated water impact negatively on quality of life of these patients. This survey was carried out to assess the HD water quality in Lagos, Nigeria. Ten milliliters of feed and treated water from all six HD centers in Lagos were tested for aluminum, copper, zinc, magnesium, calcium using atomic absorption spectrometry; sodium and potassium were tested using flame photometry, fluoride with molecular photoluminescence method; sulfate using turbidimetry, nitrates measured by cadmium column reduction method, chloramines and free chlorine were measured using N, N-diethyl-1-P-phenylenediamine colorimetric method. Information on sources of feed water, frequency of testing of HD water, methods of water treatment, type of water purification system and maintenance was also obtained. All centers used borehole as main source of water supply. None of the centers met Association for the Advancement of Medical Instrumentation (AAMI) guidelines for most chemical contaminants. Only chlorine (0.48 ± 0.07?mg/L) and potassium (3.9 ± 0.95?mg/L) levels met AAMI standards after treatment. Mean levels of chemical contaminants in treated water were as follows: aluminum 0.04 ± 0.01?mg/L, zinc 0.27 ± 0.08?mg/L, chloramines 0.16 ± 0.03?mg/L, fluoride 1.83 ± 0.40?mg/L, sulfate 117 ± 86.1?mg/L which were mildly elevated; calcium 126.00 ± 22.7?mg/L, sodium 179 ± 25.6?mg/L, and nitrate 70.5 ± 50.8?mg/L, which were markedly elevated; and magnesium 8.3 ± 3.38?mg/L, which was moderately elevated above AAMI recommended levels. HD water quality is poor in our environment. Concerted efforts are required to ensure good quality water for HD. PMID:22537314

299

Sub-chronic Hepatotoxicity of Anacardium occidentale (Anacardiaceae) Inner Stem Bark Extract in Rats.  

The extracts of Anacardium occidentale have been used in the management of different cardiovascular disorders in Nigeria. These have necessitated the assessment of the toxicity of this plant extract in sub-chronic administration. The inner stem bark of Anacardium occidentale was extracted with 80 % methanol and quantitatively analysed for antinutrients and some heavy metals. The phytochemical compositions and acute toxicity of the extract were determined also. Toxicity profiles of the extract on some liver function parameters were evaluated following a sub-chronic oral administration at doses of 1.44 and 2.87 g/kg. The phytochemical screening of extract revealed the presence of high amount of tannins, moderate saponins and trace of free reducing sugars. The antinutrient levels were 5.75 % (tannins), 2.50 % (oxalates), 2.00 % (saponins), 0.25 % (phytate) and 0.03 % (cyanide). The quantity of iron detected from dried crude was 8.92 mg/100 g, while lead and cadmium were non-detectable. The extract had LD(50)of 2.154g/kg p.o. in mice. Sub-chronic administration of the extract significantly increased the serum levels of alanine aminotransaminase and aspartate aminotransaminase, which are indicative of liver damage. The serum levels of alkaline phosphatase and total protein of the treated animals were not significantly increased. The effects of sub-chronically administered extract on hepatocytes were minimal as the serum alkaline phosphatase; total bilirubin and total protein levels in treated animals were not significant (p< 0.05). Thus, sub-chronic administrations of Anacardium occidentale inner stem bark extract did not significantly (p< 0.05) depress the function of hepatocytes in Wistar rats. PMID:21188045

300

Relevance of thermal environment to human health: a case study of Ondo State, Nigeria  

The interconnection between weather and climate and the performance, well-being, and human health cannot be overemphasized. The relationship between them is of both local and global significance. Information about weather, climate, and thermal environment is very important to human health and medical practitioners. The most crucial environmental information needed by medical practitioners and for maintaining human health, performance, and well-being are thermal conditions. The study used meteorological variables: air temperature, relative humidity, wind speed, solar radiation, and RayMan model as an analytical tool to compute physiologically equivalent temperature (PET) in order to assess thermo-physiological thresholds in Ondo State. The study revealed that there are marked spatial and seasonal variations in the environmental thermal conditions in the study area. The results of physiologically equivalent temperature for different grades of thermal sensation and physiological stress on human beings indicate that about 60 % of the total study period (1998-2008) fall under physiological stress level of moderate heat stress (PET 31-36 °C). In derived savannah, 32.6 % out of the total study period was under strong heat stress. In view of this, the study concluded that Ondo State may likely be prone to heat-related ailments and that some of the death recorded in the State, in recent times, may be heat-related mortality, but this is difficult to ascertain because there is no postmortem records in Nigeria where it could be confirmed. This type of study is relevant to help government to improve health care interventions and achieve Millennium Development Goals in health sector.

 
 
 
 
301

Delivering sustainable development benefits through the clean development mechanism[A background paper for the COP-11 Side Event : promoting the developmental benefits of the CDM : an African case study  

The clean development mechanism (CDM) was established under the Kyoto Protocol to support sustainable development objectives and to provide cost-effective initiatives for emissions reductions. This paper presented details of the Pembina Institute's Small Project Facility (SPF), which was established to address gaps in CDM deployment in some developing countries. The aim of the SPF is to promote small community-based renewable energy projects. Other objectives include increasing CDM opportunities in countries and regions with existing barriers, and supporting communities and non-governmental organizations and other potential project hosts in the preparation of project documents. An additional aim is to link Canadian CDM investors with viable community-based projects from developing countries. A partner organization in each country provides a local base of operation to identify potential project developers, organize training workshops and monitor document preparation. To date, project developers have demonstrated an eagerness to participate in the facility as implemented in India, Kenya and Nigeria. Interest has stemmed primarily from having access to alternative project financing. It was suggested that developers of small-scale CDM projects need ongoing assistance with respect to baseline selection, completion of project design documents and assessment of the financial viability of using carbon financing. Over the past 4 years, the SPF has supported the development of 8 small community-based CDM projects in India and 5 in Kenya. It was anticipated that the projects will make significant contributions to the development of participant communities through improved services, income generation, household savings, and local and environmental health benefits. It was suggested that project-level sustainable development criteria will offer a means to screen projects based on their contributions to sustainable development. A lack of knowledge about the CDM should also be addressed. The aggregation of small-scale projects into bundles was recommended in order to attract buyer interest and limit the risk to individual project developers.

302

Climate change mitigation policy paradigms — national objectives and alignments  

The aim of this paper is to assess how policy goals in relation to the promotion of green growth, energy security, pollution control and greenhouse gas (GHG) emissions reductions have been aligned in policies that have been implemented in selected countries during the last decades as a basis for discussing how a multi objective policy paradigm can contribute to future climate change mitigation. The paper includes country case studies from Brazil, Canada, China, the EuropeanUnion (EU), India, Japan,Mexico, Nigeria, South Africa, SouthKorea and the United States covering renewable energy options, industry, transportation, the residential sector and cross-sectoral policies. These countries and regions together contribute more than two thirds of global GHG emissions. The paper finds that policies that are nationally driven and that have multiple objectives, including climate-change mitigation, have been widely applied for decades in both developing countries and industrialised countries. Many of these policies have a long history, and adjustments have taken place based on experience and cost effectiveness concerns. Various energy and climate-change policy goals have worked together in these countries, and in practice a mix of policies reflecting specific priorities and contexts have been pursued. In this way, climate-change mitigation has been aligned with other policy objectives and integrated into broader policy packages, though in many cases specific attention has not been given to the achievement of large GHG emission reductions. Based on these experiences with policy implementation, the paper highlights a number of key coordination and design issues that are pertinent to the successful joint implementation of several energy and climatechange policy goals.

303

Antioxidant and hepatoprotective properties of polyphenol extracts from Telfairia occidentalis (fluted pumpkin) leaves on acetaminophen induced liver damage.  

In this study the antioxidant and hepatoprotective properties of free and bound polyphenols from Telfairia occidentalis (darkish green leafy vegetable popularly used in soup and folk medicine for the management of many diseases in Nigeria) leaves were compared. Free soluble polyphenols were extracted with 80% acetone, while the bound polyphenols were extracted from the acid and alkaline hydrolyzed residue of the leaf from free soluble polyphenols using ethyl acetate. The total phenol, DPPH free radical scavenging ability and reducing property were determined; subsequently the ability of the extracts to prevent acetaminophen (megadose) induced liver damage in rats were also assessed. Change in serum Glutamate Oxaloacetate Transaminase (GOT), Glutamate Pyruvate Transaminase (GPT), alkaline phosphatase (ALP), albumin, total protein and bilirubin were also determined. The results of the study revealed that the free soluble polyphenols content in the vegetable were significantly higher (p0.05) in serum bilirubin, albumin, globulin and total proteins in the rats. However, simultaneous intubations of some of the rat with 10 mg or 20 mg mL(-1) of T. occidentalis leaf extract (free soluble or bound polyphenols) along side with the acetaminophen caused a significant decrease (p<0.05) in serum ALP, GOT and GPT (except those intubated with bound polyphenols). Free soluble polyphenols had higher protective effect on the liver than the bound polyphenols; however there action were not dose-dependent. It could be inferred that both soluble free and bound polyphenols extracts of T. occidentails leaf have antioxidant and hepatoprotective properties, however soluble free polyphenols had significantly higher antioxidant and hepatoprotective properties than the bound polyphenols. PMID:19070082

304

Risk of medical sharps injuries among Chinese nurses  

Background Mortuary workers like other health workers are exposed to blood borne pathogens at work. A baseline assessment is important to plan for programmes to safeguard the health of workers. The aim of this study is to determine exposure rates to blood among mortuary workers in teaching hospitals in South West Nigeria. Methods A descriptive cross sectional study was carried out between March and May 2008. All mortuary workers working in six (6) teaching hospitals, 80 in total were included in the study. Data was collected with the aid of a 15- item self administered questionnaire. Data was analysed with the aid of EPI-INFO 2002. Statistical associations were explored using odds ratio and confidence intervals. Results A total of 76 respondents completed questionnaire giving a response rate of 95%; 3 males and 1 female declined to participate, the mean age of respondents was 38.2 years, 48(72.6%), 53(85.5%) and 50(73.5%) of the workers had been exposed to blood through cuts, blood splash and needle stick injury. Duration at work was significantly associated with blood splash. Workers who had worked 5years and above were 0.10 times (95% confidence interval 0.00–.0.78) as likely to experience blood splash compared to those who had worked under 5 years. Only 5(10.4%) of workers with needle stick injury had completed three doses of Hepatitis B vaccine. The specific confirmation by antibody titre was however not done in this study. Conclusion Exposure to blood was very common with blood splash emerging as the most common route of exposure. There is a need for vaccination of all mortuary workers with three doses of Hepatitis B Vaccine to protect their health. In addition, education of workers on risks and institution of standard operating procedure are crucial to safeguard the health of mortuary workers. PMID:12163861

305

Design of a multispectral digital colposcope  

Measurement quality assurance plans for optical devices should be a mandatory part of grant funding submissions and should explicitly affect scoring during review. These should include calibration strategy, standards selection strategy, performance verification plan, performance validation plan and thorough preclinical performance validation. A multispectral digital colposcope (MDC) has been designed to collect image data from patients as part of an NIH sponsored clinical trial, based on a technology assessment model. Calibration strategy, standards selection and performance verification methods are presented that may be used as a template for smaller groups or more limited studies. With the MDC, red green and blue fluorescence images are captured under ultraviolet light excitation and red and green images are captured under blue light excitation. Red, green and blue reflectance images are captured under broadband white light illumination from a metal halide lamp in three modes - ordinary reflectance, and with polarized illumination in combination with parallel and cross-polarized filtered imaging. The highly automated system was designed to collect images of the cervix prior to and following the application of acetic acid. Three systems have been built and will be operated in clinics in Vancouver, Canada, Houston, Texas and other locations in the developed and developing world including Nigeria. The system is designed with a comprehensive set of calibration and performance verification standards, based on our experience with large scale multi-center spectroscopy clinical trials and measurements are made frequently prior to and following patient measurements. Automated performance verification procedures are being designed based on measurements made during pilot studies to facilitate larger clinical trials.

306

Oral health of psychiatric patients: the nurse's perspective.  

To cite this article: Int J Dent Hygiene10, 2012; 245-249 DOI: 10.1111/j.1601-5037.2011.00537.x Azodo CC, Ezeja EB, Omoaregba JO, James BO. Oral health of psychiatric patients: the nurse's perspective. Abstract:? Objective:?To assess nurses' perspectives on character, prevalence and cause of oral diseases among psychiatric patients and also their approach and suggestions in relation to the care of oral problems. Materials and Methods:?A questionnaire-based cross-sectional survey of all cadres of nurses (n?=?136) at the Federal Psychiatric Hospital, Benin City, Nigeria, was conducted between December 2010 and January 2011. Results:?Two-thirds (67.6%) of the respondents reported that psychiatric in-patients in comparison with the general population have a higher occurrence of oral and dental problems. Commonly cited reasons for the poor oral health of patients included as follows: sedation for long periods, lack of care by family, psychopathological symptoms, poor access to dentists and lack of oral hygiene advice. The common oral health complaints received by the respondents included toothache, pain from the gums and inability to open the mouth. Majority (91.4%) of respondents claimed to be presently involved with oral care of psychiatric in-patients but oral care delivery is however bedevilled with lot of barriers like uncooperativeness of patients and lack of oral care materials. Conclusion:?Oral complaints received are frequent and numerate with limited palliative action rendered. Attaching dentists to psychiatric hospitals and regular training of psychiatric nurses on oral care delivery are recommended to comprehensively cater for the oral health problems of psychiatric in-patients. PMID:22192470

307

Occurrence and accumulation of mercury in two species of wild grown Pleurotus mushrooms from Southeastern Nigeria.  

The aim of this study was to evaluate the degree of contamination and intake rates, as well as the risk of Hg contained in two wild species of Pleurotus mushrooms--Oyster Mushroom (P. ostreatus) and King Tuber Mushroom (P. tuber-regium)--which are widely consumed in southeastern Nigeria; and to also assess their potential to accumulate Hg. The mean Hg concentrations in caps of P. ostreatus from distant sites of Ekeoba, Ntigha, and Ubakala in Abia State, were 31±11, 28±8, and 29±5 ng g(-1) dry weight, respectively; while the mean concentrations for stipes were 37±5, 36±17, and 28±6 ng g(-1) dw, in the respective communities. The caps and stipes were characterized by a mean bioconcentration factor value of ?2, indicating that P. ostreatus is a very weak Hg accumulator and probably takes in Hg solely from the wooden substratum. Sclerotia of P. tuber-regium, purchased from five different regional markets: Ukwunwangwu (Uturu), Ekeama (Umuobiala), and Ahonta (Eluama) of Abia State; and from Abakpa market and Eke-Okigwe of Imo State; contained Hg in total range of 3.3 to 180 ng g(-1) dw. A meal consisting of 300 g of caps and stipes of P. ostreatus, or of fresh sclerotia of P. tuber-regium, would expose a consumer to <1.2, and between 0.39 and 1.2 ?g Hg, respectively; and, if eaten daily for a week, would contribute less than 0.03%, and between 0.76% and 2.3% of the provisionally tolerable weekly intake (PTWI). The consumption of P. ostreatus and sclerotia of P. tuber-regium harvested from the areas investigated, therefore, poses no toxicological or health risks to the inhabitants. PMID:22818845

308

Rangewide population genetic structure of the African malaria vector Anopheles funestus.  

Anopheles funestus is a primary vector of malaria in Africa south of the Sahara. We assessed its rangewide population genetic structure based on samples from 11 countries, using 10 physically mapped microsatellite loci, two per autosome arm and the X (N = 548), and 834 bp of the mitochondrial ND5 gene (N = 470). On the basis of microsatellite allele frequencies, we found three subdivisions: eastern (coastal Tanzania, Malawi, Mozambique and Madagascar), western (Burkina Faso, Mali, Nigeria and western Kenya), and central (Gabon, coastal Angola). A. funestus from the southwest of Uganda had affinities to all three subdivisions. Mitochondrial DNA (mtDNA) corroborated this structure, although mtDNA gene trees showed less resolution. The eastern subdivision had significantly lower diversity, similar to the pattern found in the codistributed malaria vector Anopheles gambiae. This suggests that both species have responded to common geographic and/or climatic constraints. The western division showed signatures of population expansion encompassing Kenya west of the Rift Valley through Burkina Faso and Mali. This pattern also bears similarity to A. gambiae, and may reflect a common response to expanding human populations following the development of agriculture. Due to the presumed recent population expansion, the correlation between genetic and geographic distance was weak. Mitochondrial DNA revealed further cryptic subdivision in A. funestus, not detected in the nuclear genome. Mozambique and Madagascar samples contained two mtDNA lineages, designated clade I and clade II, that were separated by two fixed differences and an average of 2% divergence, which implies that they have evolved independently for approximately 1 million years. Clade I was found in all 11 locations, whereas clade II was sampled only on Madagascar and Mozambique. We suggest that the latter clade may represent mtDNA capture by A. funestus, resulting from historical gene flow either among previously isolated and divergent populations or with a related species. PMID:16313589

309

Extracts of Ficus exasperata leaf inhibit topical and systemic inflammation in rodents and suppress LPS-induced expression of mediators of inflammation in macrophages.  

The leaves of Ficus exasperata are mashed and prepared as poultices that are placed on swellings, wounds, and arthritic joints to relieve swelling and pains by the Igede tribal community of Nigeria. The leaf and stalk are also squeezed and used to mitigate itching or inflammation. These claimed benefits inspired this study in which topical and systemic (acute, chronic) anti-inflammatory activities of a methanol/methylene chloride leaf extract of F. exasperata (MFE) were assessed in rodents. Effects of an aqueous leaf extract (AFE) on lipopolysaccharide-induced expression of interleukin-1? (IL-1?), tumor necrosis factor (TNF)-?, and inducible nitric oxide (iNO) were also investigated in murine bone marrow-derived macrophage (BMDM) cultures. Treatment of rats with MFE (200 and 400?mg/kg) led to significant inhibition of acute and chronic inflammation induced by, respectively, agar and formaldehyde in the paws. Topically, pre-application of mice with MFE (5 µg/ear) also significantly inhibited (by up to 21%) ear edema induced by xylene. In vitro, pre-treatment of BMDM with 5-100 µg AFE/ml significantly inhibited IL-1?, TNF?, and iNO production in a dose-related manner. BMDM viability was not significantly affected AFE at concentrations up to 200 µg/ml. Initial studies showed that flavonoids, alkaloids, and terpenoids were the predominant phytoconstituents in each extract. In conclusion, the results of the various investigations indicated that F. exasperata leaf extracts possess anti-inflammatory properties that could underlie the benefits associated with the folklore use of the plant. The results also show that the extracts may be acting through a suppression of mediators of inflammation, such as IL-1?, TNF?, and iNO. PMID:23098056

310

Chemical properties of urban waste ash produced by open burning on the Jos Plateau: implications for agriculture.  

Urban centres produce most of the world's waste and between a third and a half goes uncollected. The answer to the problem of waste disposal lies partly in agriculture, as waste can be extremely nutrient-rich. In the last decade there has been a tremendous increase in the developing world in total city area under informal food production and there are many examples of waste recycling onto the urban or peri-urban plots. Farmers on the Jos Plateau, Nigeria, have developed a successful soil fertility management strategy based on the combination of inorganic fertilisers, manure and urban waste ash. This study sought to provide some preliminary data on urban waste ash produced by open burning and used in farming in a developing country. Ash samples were collected from different locations around Jos and tested for C, N, pH, P, Na, K, Ca, Mg, Fe, Mn, Zn, Cu, Ni, Cd and Pb. It was found that ash is an effective liming material (because of the high pH, and high Ca, Mg and K contents), and has the potential to contribute significant quantities of micro-nutrients such as Mn, Zn and Cu. Ash, however, is far from being a homogenous material and its variability means that its fertilising potential will vary between batches and that, even if mean and median levels are low, there is the risk of the formation of localised areas of soil with excessive heavy metal contents (this is particularly the case with Pb). Further research is required to determine the plant-availability of these elements in the ash and to assess the wider environmental and health implications of uncontrolled, open burning of waste as a means of producing ash for agricultural purposes. PMID:14967513

311

Assessment of the Level of Male Involvement in Safe Motherhood in Southern Nigeria.  

Pregnancy and the events surrounding it are generally viewed as feminine issues exclusively for women. In sub-Saharan Africa, believing that pregnancy and the events that follow are guided by nature, a lot of superstition is attributed in the event of complications, which result in poor maternal outcomes. Maternal mortality remains a public health challenge worldwide, and Nigeria has one of the highest levels of maternal mortality in the world (545 per 100,000 live births). The involvement of men in ensuring and enhancing maternal health was a great idea hatched at the Cairo conference in 1994, but since then, not much has been done in practical terms in most of the developing world. This study is aimed at assessing the level of male involvement in their spouses' reproductive health events before pregnancy, during pregnancy, delivery and peuperium. A descriptive cross-sectional study design in which questionnaires were incorporated with an in-depth interview was used and a multistage sampling technique was used to select respondents. After house numbering, a total of 400 houses were selected from a cluster of four quarters in Patani Town. Participants were systematically sampled from each household using random number table. Results from data collected on the study indicated that (61.1 %) of men were aware of maternal health issues and the level of education was shown to have significant relationship (?² = 5.139, df = 3, p = 0.162) with the knowledge of maternal health issues. Though the level of male involvement in safe motherhood was shown to be of good proportion, strategies to create awareness on male support for their parous spouses should be given a broader frontier, both in clinics, household and community levels. Men should be more involved than before, as they have a priceless role to play towards a significant improvement in maternal health. The Government, development partners and NGOs at all levels should be committed with a strong political will in this regard. PMID:23054420

312

Society for College Science Teachers: "What? Professors Evaluating Themselves? Are You Out of Your Mind?" In Defense of Faculty Self-Evaluation  

Self-assessment is a win-win evaluation system. Evaluees, not the department or university, control the process by selecting the evaluation criteria. Self-assessment also eliminates the uncomfortable and burdensome task of peer evaluation. Self-evaluation allows for a thoughtful assessment of yearly progress on objectives, and challenges to meeting those objectives. It is by far the fairest, least aggressive, and most reliable way to evaluate college faculty. Finally, unlike other forms of assessment, self-evaluation can never be performed without an investment from the professor being reviewed.

313

If U Can Graff These Numbers--2,15,6--Your Stat Literit.  

This paper identifies and assesses key ideas in data analysis (or statistics) that should be at the focus of middle school mathematics instruction. Items that can be used to assess some of the complex objectives of data analysis are located. The search includes a collection of items released by the National Assessment of Educational Progress (NAEP) and various state exams. The nature of items being used on large-scale state assessments is described in detail. Views on what should be taught and some items that are designed to tap those ideas are presented. (SOE)

314

The value of cartilage biomarkers in progressive knee osteoarthritis: cross-sectional and 6-year follow-up study in middle-aged subjects.  

To determine the possible diagnostic and prognostic value of cartilage biomarkers in early-stage progressive and nonprogressive knee osteoarthritis (OA) in a population-based cohort of middle-aged subjects with chronic knee pain. Design tibiofemoral (TF) and patellofemoral (PF) radiographs were graded in 128 subjects (mean age at baseline, 45 ± 6.2 years) in 2002, 2005, and 2008. Cartilage degradation was assessed by urinary C-telopeptide fragments of type II collagen (uCTx-II), synthesis by serum type II A procollagen N-terminal propeptide (sPIIANP), and articular tissue turnover in general by cartilage oligomeric matrix protein (sCOMP). Several diagnostic associations were found between all studied biomarkers and progressive osteophytosis. COMP and CTx-II had a predictive value for subsequent progressive osteophytosis in multiple knee compartments and in case of CTx-II-also for progressive JSN. Over the first 3 years (2002-2005), significant associations were observed between COMP and progressive osteophytosis, whereas 3 years later (2005-2008) between CTx-II and progressive JSN. Thus, the associations between cartilage markers (COMP, CTx-II) and progression of radiographic OA features-osteophytes and JSN-were different between 2002-2005 and 2005-2008. Logistic regression revealed that for every unit increase in COMP level, there was 33 % higher risk for TF osteophyte progression. During early-stage OA, the presence and progression of osteophytosis is accompanied by increased level of cartilage biomarkers. This is the first study to demonstrate biochemical differences over the course of knee OA, illustrating a phasic nonpersistent character of OA with periods of progression and stabilization. PMID:22821260

315

Prospective study of the progression of low-grade dysplasia in ulcerative colitis using current cancer surveillance guidelines  

AbstractBackground: The goal of this study was to assess the natural history of low-grade dysplasia (LGD) and its risk of progression in ulcerative colitis (UC) patients by prospective endoscopic surveillance. Methods: Forty-two UC patients with LGD were followed prospectively using a uniform approach to surveillance colonoscopy with an average of 43 biopsies per exam. The interval between colonoscopies ranged from 3-12 months. Progression was defined as development of high-grade dysplasia (HGD) or cancer at subsequent colonoscopy or at colectomy. Univariate and multivariate analysis were performed to identify risk factors associated with progression. Results: Patients were followed for an average of 3.9 years (range 1-13). Over that period 19% (8/42) of patients progressed to advanced neo...

316

On Reliability Based Optimal Design of Concrete Bridges  

In recent years important progress has been made in assessment of the lifetime behaviour of concrete bridges. Due to the large uncertainties related to the loading and the deterioration of such bridges, an assessment based on stochastic modelling of the significant parameters seems to be only relevant modelling. However, a great number of difficulties are involved in the modelling. The main purpose of this paper is to give an overview of areas where more research is needed and in some cases propose solutions.

317

Naturally fractured tight gas reservoir detection optimization. Quarterly report, October 1--December 31, 1994  

This progress report covers the following tasks: Computational geochemistry (Indiana University Laboratory); and geologic assessment of the Piceance Basin. Computational geochemistry covers; three- dimensional basin simulator; stress solver; two-dimensional basin simulator; organic reactions and multi-phase flow; grid optimization; database calibration and data input; and Piceance Basin initial simulation. Sub-tasks under geologic assessment of the Piceance Basin include: structural analysis; reservoir characterization; stratigraphic interpretation; seismic interpretation; and remote sensing interpretation.

318

Current status of accident sequence precursor program for operational events at nuclear power plants  

In this report, the author describes the findings obtained from his experience of accident sequence precursor (ASP) assessment during 1-year staying in Nuclear Regulatory Commission (NRC) and presents the progress in the ASP program and its technical issues based on the open informations from literatures. Probabilistic Safety Assessment (PSA) aiming at analysis and assessment for the occurrence frequency, progressing processes and influences on the public health and the environment of various accidents which might happen in nuclear power plants, has been utilized in many plants since 1975 and Risk Assessment Review Group (1978) concluded that to assess the potential significance of ASP using a similar way to the WASH-1400 method is important. The ASP program was thus started in NRC. ASP assessment is a method to quantitatively evaluate the significance of accident and failure incidents developed in nuclear power plants from an aspect of the possibility for occurrence of core damage accident resulting from them, by the means of PSA. This method has been developed and utilized by NTC. Since the accuracy of assessment has been improved accompanying to the recent advances in PSA procedures. ASP assessment is now widely utilized not only for analysis and assessment of operational events but also for various purposes including the examination of validity for the results from PSA. (M.N.)

319

Erythropoietin in the prevention of experimental burn progression  

AbstractBackground: Damage control is essential in first aid of burn lesions. The aim of the present study was to investigate whether systemic erythropoietin (EPO) administration could prevent secondary burn progression in an experimental model. Methods: The burn comb model creates four rectangular burn surfaces intercalated by three unburned zones prone to progression. Twenty-one Wistar rats were randomized to a control group or to receive intraperitoneal EPO (500 units per kg) once a day for 5 days starting 45 min (EPO45min) or 6 h (EPO6h) after burn injury. Histological analyses assessing burn depth, inflammation and neoangiogenesis, planimetric evaluation of burn progression, and laser Doppler flowmetry to assess perfusion were performed after 1, 4 and 7 days. Final scarring time and c...

320

Female genital multilation  

Background With the advent and widespread use of highly active antiretroviral therapy for the treatment of human immunodeficiency virus (HIV), persons living with HIV/acquired immune deficiency syndrome (AIDS) are living good quality, longer, and healthier lives. Many couples affected by HIV, both serodiscordant and seroconcordant, are beginning to consider options for safer reproduction. The aim of this study was to assess the reproductive health concerns among persons living with HIV/AIDS in the Niger Delta of Nigeria. Methods and results The subjects were aged 18–58 (mean 41.25 ± 11.50) years, with 88 males (45.1%) and 107 females (54.9). Of the 195 subjects studied, 111 (56.9%) indicated a desire to have children. The main reasons for wanting to procreate included ensuring lineage continuity and posterity (52.3%), securing relationships (27.0%), and pressure from relatives to reproduce (20.7%). Single subjects were more inclined to have children (76.3%) compared with married (51.5%), widowed (18.2%), and separated/divorced subjects (11.1%, P = 0.03). Of the 111 subjects who indicated their desire to have children, women were more inclined to have children (64.5%) than men (47.7%). The major concern among the 84 (43.1%) subjects not desiring more children were the fear of infecting a serodiscordant partner and baby (57.1%), fear of dying and leaving behind orphans (28.6%), and fear that they may become too ill and unable to support the child financially (14.3%). Persons with no formal education were more likely to have children irrespective of their positive HIV status (66.7%) than persons educated to tertiary education level (37.0%, P = 0.01). Of 111 subjects who desired to have children, only 58% had attended reproductive health counseling with HIV counselors. Reasons for not seeking advice were anticipated negative reactions and discrimination from counselors. A significant number of subjects were only aware of some of the reproductive health options available to reduce the risk of infecting their partners and/or baby, such as artificial vaginal insemination, intrauterine insemination, cesarean section, avoidance of breast feeding, and offering prenatal pre-exposure prophylaxis to the fetus. They were unaware of other options, such as sperm washing, in vitro fertilization, and intracytoplasmic sperm injection. Of the 43.1% not anticipating more children, 36.9% were anticipating adoption. Conclusion Our study has shown that a significant number of HIV-infected persons in the Niger Delta of Nigeria desire to have children irrespective of their positive serostatus. There is the need to support the sexual and reproductive rights of HIV-infected individuals. Additional training needs to be offered to HIV counselors on evidence-based best and affordable practices regarding reproductive health issues among persons living with HIV. Policies that support availability and accessibility to relevant reproductive and sexual health services, including contraception and procreation, need to be developed. Public enlightenment programs on HIV are needed to reduce the stigmatization that HIV-infected persons face from family members and their communities. PMID:18438515

 
 
 
 
321

Impact of off-farm income on food security and nutrition in Nigeria  

While the poverty implications of off-farm income have been analyzed in different developing countries, much less is known about the impact of off-farm income on household food security and nutrition. Here, this research gap is addressed by using farm survey data from Nigeria. Econometric analyses a...

322

A ''SNCC'' controls the uranium production in the desert; Un SNCC controle la production d'uranium en plein desert  

In the Nigeria desert, Cogema works two uranium deposits and realizes a processing then and there. It was decided to renovate the process control installations. A centralized channel system Delta V of Emerson Process Management replaced the classical board control. The new installation is technically and economically described. (A.L.B.)

323

Sirenomelia in one of Nigerian monochorionic twins.  

A 1,600 gm baby with sirenomelia (caudal regression syndrome) associated with extensive anomalies in the internal organs occurring in one of a set of monochromic twins delivered at the Olabisi Onabanjo University Teaching Hospital (OOUTH), Shagamu, Nigeria is being reported. The baby lived for approximately twenty hours. The co-twin had no obvious malformation. PMID:15027784

324

Epidemiology and control of polioviruses in Nigeria  

Although the World Health Assembly resolved to eradicate wild poliovirus (WPV) by 2000, four countries have yet to interrupt transmission of WPVs. As of 2009, Nigeria has reported the largest burden of poliovirus of any single country for 5 of the last 6 years and been responsible for the largest o...

325

IAEA: 17 countries are candidates for nuclear energy; AIEA: 17 pays candidats a l'energie nucleaire  

In january 2011 IAEA announced that 17 countries had officially expressed their willingness to home nuclear power plants, they have filed applications for the construction of nuclear power plants. Among the countries concerned we find: Poland, Kuwait, Jordan, Morocco, Tunisia, Nigeria, Bangladesh, Thailand, Vietnam, Chile and Uruguay

326

Potential role of compressional structures in generating submarine slope failures in the Niger Delta  

The study area, offshore Nigeria, is located in one of the compressional zones within the Niger Delta, which is characterized by imbricate thrust structures. Although the low mean slope angle (around 2°), bathymetry data from the study area have shown the existence of several submarine landslides wh...

327

The ''Petro Violence '' in the Oil rich Niger Delta of Nigeria : A Moral Accessment  of the Conflict between Shell and Its Host Communities  

ABSTRACT Niger Delta of Nigeria is a region characterized with conflict commonly conceptualized as ‘‘petro-violence’’. This violence  between Shell and its host communities has lasted over four decades. While the activities of Shell and other oil companies destroy the ecology of the region , the o...

328

Exploration gaps exist in Nigeria`s prolific delta  

The Niger delta region of the Republic of Nigeria is Africa`s largest oil producing area. It is clear that Nigeria will continue to contribute significantly to world petroleum production well into the 21st century: with increases in recoverable oil reserves in the Niger delta onshore and offshore; the promising potential of the Niger delta deepwater region; and a lesser but not insignificant contribution from the unexplored onshore Benue trough, part of the mid-African rift system, which has already proved to hold substantial oil reserves in the Doba basin of neighboring Chad. This is the first of five parts on Nigeria`s oil and gas potential. The later articles deal with Niger delta oil reserves and production, Niger delta gas reserves, the delta`s deepwater region, and the Benue trough and onshore cretaceous rift basins. This article deals with the geologic setting of the Niger delta-Benue trough region, the synrift deposits, marine sedimentation, margin evolution, geologic strata and reservoirs, reservoir character, structure and traps, hydrocarbon types, geotemperatures, and source rock quality.

329

Medio siglo de publicaciones botánicas en la Revista de Biología Tropical  

Abstract in english Over its first half century the Revista de Biología Tropical published many papers and supplements dealing with the botany. However, the Revista is not a primary botanical journal. A wide variety of topics and geographic sources have been included, taking into consideration species from the Neotropics, but also from India and Nigeria. A complete index of botanical papers is presented.

330

Global Distribution and Density of Constructed Impervious Surfaces  

Sep 21, 2007 ... density of ISA on a one-km2 grid based on two coarse resolution indicators .... lights from natural gas flares present on land areas in places such as Nigeria .... For the conterminous USA the aggregate area of ISA in the USGS ...

331

Distribution of ABO and Rh-D blood groups in the Benin area of Niger-Delta: Implication for regional blood transfusion  

ABO and Rhesus (Rh) blood group antigens are hereditary characters and are useful in population genetic studies, in resolving medico-legal issues and more importantly in compatibility test in blood transfusion practice. Data on frequency distribution of ABO and Rh-D in Niger-Delta region of Nigeria ...

332

Providing safe medicines for children in Nigeria: The impediments and remedies.  

Promoting safety of medicines for children is a global concern which has prompted the World Health Organization (WHO) to launch a campaign of "Making Medicines Child Size". Children in Nigeria were once victims of unethical clinical medicine trials and repeated victims of use of fake and adulterated medicines. Considering the magnitude of harms children had suffered in Nigeria from the use of medicines, there is a need for literature review to identify the factors preventing children from accessing safe medicines and to suggest remedies to the problems. Lack of access to up- to- date medicine information, lack of training and research in pediatric clinical pharmacology, deficiencies in undergraduate and postgraduate teaching of medicine risk management and clinical pharmacology and therapeutics, irrational medicine use due to lack of pediatric focus on essential medicine list and inappropriate home storage of medicines by parents, lack of evidence- based medicine (EBM) practice, lack of national adverse drug reaction surveillance among children, and weak national drug policies were the major problems identified. It is to be hoped that development and provision of a pediatric national drug formulary for health professionals in Nigeria, creating a comprehensive national pediatric drug research network in collaborations with developed countries, reviewing the undergraduate and postgraduate curriculum in pediatrics to include teaching of basic elements of rational prescribing, drug dose calculations, adverse drug reactions and pharmacovigilance, increasing access to essential medicines for children, postgraduate teaching of EBM, and strengthening of the national drug policies would improve children's access to safe medicines in Nigeria. PMID:20935418

333

Identification of risk factors associated with highly pathogenic avian influenza H5N1 virus infection in poultry farms, in Nigeria during the epidemic of 2006–2007  

We conducted a matched case–control study to evaluate risk factors for infection with highly pathogenic avian influenza (HPAI) H5N1 virus in poultry farms during the epidemic of 2006–2007 in Nigeria. Epidemiologic data were collected through the use of a questionnaire from 32 case farms and 83 contr...

334

Evolutionary Dynamics of Multiple Sublineages of H5N1 Influenza Viruses in Nigeria from 2006 to 2008 ? †  

Highly pathogenic A/H5N1 avian influenza (HPAI H5N1) viruses have seriously affected the Nigerian poultry industry since early 2006. Previous studies have identified multiple introductions of the virus into Nigeria and several reassortment events between cocirculating lineages. To determine the spat...

335

Evidence of climatic change in Nigeria based on annual series of rainfall of different daily amounts, 1919-1985  

Annual series of light rainfall, moderate rainfall and heavy rainfall are computed for 4 zones arranged from south to north in Nigeria: Coastal, Guinea-Savanna, Midland and Sahelian zones. Daily rainfall data for the period 1919-85 are utilized. Each series is examined for evidence of change in structure in terms of pattern of decrease and increase in dry and wet years, the overall trend, and the occurrence of runs of dry and wet years. The northern Nigeria (Midland and Sahel) heavy rainfall series and the Sahel moderate rainfall series are found to depict evidence of climatic change as defined by Landsberg (1975) that climatic conditions must change to a new equilibrium position with the values of climatic elements changed significantly. On the other hand Landsberg's definition of climatic fluctuations as involving temporary deflection which can revert to earlier conditions is found to fit the 4 regional light rainfall series and the Midland area moderate rainfall series. The southern Nigeria moderate and heavy rainfall series are found to depict only evidence of high frequency oscillations about a stable long-term mean. The recent drought in Nigeria north of about 9{degree}N is shown to be associated with a large decline in moderate and heavy rainfalls over this part of the country. 23 refs., 4 figs., 3 tabs.

336

Electronic Waste - Not in my backyard  

This report examines the economical effects, and environmental and health wise risks of exporting electronic waste from the European Union to Nigeria. The report accounts for the global situation on e-waste and presents data from the EU on e-waste and illegal shipments. It also shows data on amounts...

337

A clinicopathological study of human yellow fever*  

During an epidemic of yellow fever in the Jos Plateau area of Nigeria, 9 adult males with clinically diagnosed yellow fever were studied by haematological, biochemical, virological, serological, and liver biopsy methods. The ages of the patients ranged from 20 to 55 years and the duration of illness...

338

Lassa fever in Onitsha, East Central State, Nigeria, in 1974  

Three cases of Lassa fever occurred in Onitsha, East Central State, Nigeria, in January and February 1974. The first case was a 19-year-old Nigerian; the other 2 cases were German missionary physicians at St Charles Borromeo Hospital, Onitsha, one of whom cared for the patient who was the first case...

339

Genetic Diversity among Lassa Virus Strains  

The arenavirus Lassa virus causes Lassa fever, a viral hemorrhagic fever that is endemic in the countries of Nigeria, Sierra Leone, Liberia, and Guinea and perhaps elsewhere in West Africa. To determine the degree of genetic diversity among Lassa virus strains, partial nucleoprotein (NP) gene sequen...

340

Recent isolations of Lassa virus from Nigerian rodents  

Rodents were trapped in the Benue-Plateau and North-Eastern States of Nigeria where Lassa fever had been reported in previous years. Eight Lassa virus strains were isolated from tissues and blood of rodents identified in the field as being of 3 different species: Mastomys natalensis, Rattus rattus, ...

 
 
 
 
341

Twin-screw-multiphase-boosting technology in the 90s: the decade of pioneers. Pt. B - field application at SPDC in Nigeria  

The Shell Petroleum Development Company of Nigeria Limited (SPDC) is the largest oil and gas exploration and production company in Nigeria. It is the operator of a joint venture in which The Nigerian Petroleum Development Company of Nigeria (NNPC) holds 55 per cent, Shell 30 per cent, Elf 10 per cent and Agip 5 per cent. The first commercial oil field at Oloibiri in the Niger Delta was discovered in 1956 leading to the first export of oil in Nigeria in 1958. Currently, SPDC produces almost half the country's oil from more than 90 oil fields in the Niger Delta area. It also supplies more than half the country's commercial gas. Its oil mining lease area of 31,000 square kilometres contains more than half the country's oil and gas reserves. The scale of the company's operation is massive, involving an infrastructure of 6,200 kilometres of pipelines, more than 1,000 wells, 87 production stations, seven gas (NAG) plants and two large oil terminals at Forcados and Bonny. The company's operations are managed via two autonomous divisions, (East and West), which are based in Warri, Delta State, and Port Harcourt, Rivers State, respectively, with a small corporate centre in Lagos. (author)

342

1988 saw major efforts to spur foreign interest  

This article discusses how Africa's large producers are offering incentives to attract exploration. Egypt is pushing new gas development, while Nigeria announced reduced taxes to lure foreign operators. Gabon has rejuvenated its production with discovery of a large new oil field. Libya is offering liberal concession terms, though the status of U.S. firms is uncertain.

343

Public housing delivery in Nigeria: problems and challenges  

Paper presented at the XXXIII IAHS World Congress on Housing, 27-30 September 2005,"Transforming Housing Environments through Design", University of Pretoria. , In Nigeria political, economic, social and environmental factors and the huge foreign exchange accumulated from the rise in oil price in the 1...

344

Soil nutrient dynamics as influenced by organomineral fertilizers and tea seedlings nutrient uptake in Nigeria  

Cocoa husk, cow dung, poultry droppings, siam weed - Chromolaena odorata and tea fluff are common farm wastes in Nigeria. They were used as manures as sole and in combination with inorganic fertilizer as organominerals (OMF), compared to NPK (5:l:1) a reference fertilizer, to supply 150 kg N ha-l to...

345

Bits and Pieces ehk kolumna. White Label : No More Rokkstars. Kuula / DJ Pickney Tiger  

Popmuusikauudised. Ansamblist No More Rockstars. Heliplaatidest: "Nigeria 70 Lagos Jump" Foxboro Hot Tubs "Stop Drop and Roll!!!", Maikameikers "Kriminaalne Elevant "Kuul", Vaiko Eplik ja Eliit "3. Kosmoseodüsseia", Zetod "Lätsi tarrõ tagasi", Konono NO 1 "Live at Coleur Cafe", Hadouken! "Music for an accelerated culture", "Quiet Village - Silent Movie"

346

Local involvement in harnessing crude oil and natural gas in Nigeria  

Vast financial investments have been made in the upstream crude-oil and natural-gas (CONG) sector in Nigeria, but have not resulted in significant benefits for most Nigerians. The associated major activities, e.g., exploration, drilling, production, well intervention and service provision r...

347

The Contribution of Bayesian Networks to Manage Risks of Maritime Piracy against Oil Offshore Fields  

In recent years pirate attacks against shipping and oil fields have continued to increase in quantity and severity. For example, the attack against the Exxon Mobil oil rig in 2010 off the coast of Nigeria ended in the kidnap of 19 crew members and a reduction in daily oil production of 45,000 barrel...

348

Temporal Changes as Depicted on Orbital Photographs of Arid ...  

Processes typical of arid environments can be monitored from space by ... tion west of the Nile Delta of approximately 1108 km2 in 10 years; .... the deposition of the sand is not constrained by .... ders of Niger, Nigeria, Cameroon, and Chad in ...

349

Artocarpus Communis Forst. Root-Bark Aqueous Extract- and Streptozotocin-Induced Ultrastructural and Metabolic Changes in Hepatic Tissues of Wistar Rats  

Decoctions and infusions of Artocarpus communis (Forst.) (family: Moraceae) root-bark are commonly used traditionally among the Yoruba-speaking people of Western Nigeria as folk remedies for the management, control and/or treatment of an array of human diseases, including type 2, adult-onset diabete...

350

Development and implementation of preventive-maintenance practices in Nigerian industries  

A methodology for the development of PM using the modern approaches of FMEA, root-cause analysis, and fault-tree analysis is presented. Applying PM leads to a cost reduction in maintenance and less overall energy expenditure. Implementation of PM is preferable to the present reactive maintenance procedures (still prevalent in Nigeria). (author)

351

Cross-Location Analysis of the Impact of Household Socioeconomic Status on Participation in Urban and Peri-Urban Agriculture in West Africa  

This study explores the relation between household socioeconomic status (SES) and participation in urban and periurban agriculture (UPA) in three West African cities. We used a structured questionnaire to survey 700 randomly selected households: 250 in Kano, Nigeria, 250 in Bobo Dioulasso, Burkina F...

352

Forest Genetic Resources Conservation and Management : In managed and natural forests and protected areas (in situ)  

FAO, IPGRI/SAFORGEN, DFSCand ICRAF have cooperated on the compilation of17 booklets on the state of Forest Genetic Resources for thecountries listed below. When ordering your book please remember to write the country required on the email. Benin, Burkina Faso, Cote d\\Ivoire, Ethiopia, Gambia, Guinee, Ghana, Kenya, Mali, Mauritania, Niger, North of Nigeria, North Cameroon, Senegal, Sudan, Tchad and Togo.

353

Squamous cell carcinoma of the scrotum in a Nigerian: case report  

Squamous cell carcinoma of the scrotum is rare and to the best of our knowledge has never been reported from Nigeria. We report on a case thought to be occupation-related in a 42-year old Nigerian taxi driver who had previously been an automobile mechanic and later a long-haul truck driver. He prese...

354

Hope and violence in Nigeria  

The long history of political uncertainty and corruption in Nigeria is outlined with particular emphasis on its impact on the National Nigerian Petroleum Company (NNPC). Recent political developments and the consequent crackdown on rampant corruption has meant that there are better prospects for NNPC to begin to properly contribute to joint ventures with the major international oil companies. (UK)

355

Income risk and welfare status of rural households in Nigeria: Ekiti State as a test case  

This paper examines the impact of income risk on the level of well-being of rural households in Nigeria. While income risk is defined as the risks associated with variability in income well-being is defined in terms of the level of utility reached by a given individual. This level is a function of g...

356

Review of prostate cancer research in Nigeria  

Prostate cancer (CaP) disparities in the black man calls for concerted research efforts. This review explores the trend and focus of CaP research activities in Nigeria, one of the ancestral nations for black men. It seeks to locate the place of the Nigerian research environment in the global progres...

357

Revisiting the resource-conflict link: A systematic comparative test of causal mechanisms in four major oil-exporting countries  

Causal mechanisms and related contextual variables are crucial to the study of the resource-conflict link, but little systematic research has been done on their exact functioning. This paper contributes to the filling of this gap by comparing four major oil exporters (Algeria, Iran, Nigeria, and Ven...

358

Ethno-Veterinary Practices Amongst Small-Holder Farmers in Ekiti State, Nigeria  

This paper aimed at identifying factors influencing the use of ethno-veterinary practices amongst goat and poultry farmers in Ekiti state, Nigeria. It specifically described the socio-economic characteristics of the farmers; identified some diseases of goats and poultry with their corresponding indi...

359

Social Work Practice with Childbirth-Injured Women in Nigeria.  

Interviewed social workers in Nigeria and 127 patients suffering from childbirth injuries of vesicovaginal fistula (VVF), debilitating and chronic condition whereby woman leaks urine uncontrollably and experiences grave social consequences. Crisis intervention, social rehabilitation, fighting stigma, and discharge planning similar to American professional model were functions of social workers in addressing needs of this population. (Author/NB)

360

Communist Theory in the Nigerian Trade Union Movement  

The subject of this paper is the Nigerian Trade Union Congress (NTUC), the Communist trade union organisation in Nigeria. More specifically, it is about the central leadership of the NTUC, since the organisation is in origin and structure a central, national and Lagos-based federation of trade union...

 
 
 
 
361

Close Relationship between G8-Serotype Bovine and Human Rotaviruses Isolated in Nigeria  

A bovine rotavirus, NGRBg8, isolated from the feces of a calf with diarrhea in Nigeria was characterized by reverse transcription-PCR, nucleotide sequence analysis, and Northern blot hybridization. The nucleotide sequence of the VP7 gene of the strain was most closely related to that of a Nigerian h...

362

Epidemiological features of an outbreak of gastroenteritis/cholera in Katsina, Northern Nigeria.  

In April 1982, Katsina, in Northern Nigeria, was affected by an outbreak of gastroenteritis associated with Vibrio cholerae serotype 'Ogawa' and 662 patients were admitted to the Katsina General Hospital during a 16-week period. The outbreak affected all ages and both sexes and all parts of the town...

363

Galvanising shareholder activism: a prerequisite for effective corporate governance and accountability in Nigeria  

Shareholder activism has been largely neglected in the few available studies on corporate governance in sub Saharan Africa. Following the recent challenges posed by the Cadbury Nigeria Plc, this paper examines shareholder activism in an evolving corporate governance institutional context and identif...

364

The Enduring Legacy of the “Invisible Network” - NASA's History Office  

Over the past year, our oral history team, Rebecca Wright and Sandra Johnson, have been .... from the Federal Records Center related to the Electronics Research Center, a ..... This comprehensive text addresses all medical and public health issues ..... Signals were received by stations in Florida, Singapore, Nigeria, and ...

365

The Enduring Legacy of the “Invisible Network”  

Over the past year, our oral history team, Rebecca Wright and Sandra Johnson, have been .... from the Federal Records Center related to the Electronics Research Center, a ..... This comprehensive text addresses all medical and public health issues ..... Signals were received by stations in Florida, Singapore, Nigeria, and ...

366

Crude Oil-Degradation and Plasmid Profile of Nitrifying Bacteria Isolated from Oil-Impacted Mangrove Sediment in the Niger Delta of Nigeria  

The crude oil degradability and plasmid profile of autotrophic nitrifying bacteria, Nitrosomonas and Nitrobacter species, isolated from mangrove sediment in the Niger Delta of Nigeria were studied. The effects of temperature, pH and optical density on the utilization of different carbon sources by t...

367

Produce marketing co-operatives in West Africa  

Sum.: In the West African countries of the Ivory Coast, Ghana, Nigeria and Cameroon, cooperative societies are involved in buying coffee and cocoa from farmers. These cooperatives do not always pay exactly the producers' price as it is set by the respective governments. These deviations from the pro...

368

Critical control points of complementary food preparation and handling in eastern Nigeria.  

OBJECTIVE: To investigate microbial contamination and critical control points (CCPs) in the preparation and handling of complementary foods in 120 households in Imo state, Nigeria. METHODS: The Hazard Analysis Critical Control Point (HACCP) approach was used to investigate processes and procedures t...

369

Violence against women and girls: breaking the culture of silence  

GBV has many forms, including domestic violence, female genital cutting, rape and forced prostitution. This overview article written by guest editor Grace Osakue of Girls’ Power Initiative in Nigeria sheds some light on the complexity and pervasiveness of this issue. After describing different types...

370

Natural Immunity to Ascaris lumbricoides Associated with Immunoglobulin E Antibody to ABA-1 Allergen and Inflammation Indicators in Children  

Children putatively immune to the large roundworm Ascaris lumbricoides were identified in an area of Nigeria where infection is hyperendemic. Immunity was associated with higher levels of serum ferritin, C-reactive protein, and eosinophil cationic protein, indicating ongoing acute phase or inflammat...

371

Natural immunity to Ascaris lumbricoides associated with IgE antibody to ABA-1 allergen and inflammatory indicators in children  

Children putatively immune to the large roundworm Ascaris lumbricoides were identified in an area of Nigeria where infection is hyperendemic. Immunity was associated with higher levels of serum ferritin, C-reactive protein, and eosinophil cationic protein, indicating ongoing acute phase or inflammat...

372

Neonatal Klebsiella Septicaemia in Ibadan: Implications for Neonatal Care in Developing Countries.  

The antecedent events, clinical features, prevalence, and complications of neonatal Klebsiella septicaemia in 73 infants admitted to a special care baby unit in Nigeria are retrospectively reviewed and compared with those of 72 infants who had no risk factors for sepsis admitted to the same unit during the same period. A nosocomial acquisition of the infection was evident. (MDM)

373

Medicinal Uses of Mushrooms in Nigeria: Towards Full and Sustainable Exploitation  

For centuries, mushrooms have been appreciated as sources of food nutrients and pharmacologically important compounds useful in medicine. Yet not all the medicinal properties of mushrooms have been exploited. The above statement is more pertinent to mushrooms that are indigenous to Nigeria. There ar...

374

Geoadditive Latent Variable Modelling of Count Data on Multiple Sexual Partnering in Nigeria  

The 2005 National HIV/AIDS and Reproductive Health Survey in Nigeria provides evidence that multiple sexual partnering increases the risk of contracting HIV and other sexually transmitted diseases. Therefore, partner reduction is one of the prevention strategies to accomplish the Millenium developme...

375

Petroleum developments in Central and Southern Africa in 1964  

This review includes 43 countries, i.e., all of Africa except Morocco, Tunisia, Algeria, Libya, Egypt, and Sudan. Total annual production for Central and Southern Africa increased by 43% to 58,795,166 bbl in 1964. This increase was contributed largely by Nigeria although Gabon and Angola also recorded new highs. Congo (Brazzaville) had a 23% drop in production. No other countries are currently producing oil. Fifty-four exploratory wells were completed in 1964, of which 51.9% were successful. Twenty-one oil discoveries were made in Nigeria, one in Gabon, and one in Congo (Leopoldville), the latter's first discovery. Four gas discoveries were recorded in Nigeria as well as a gas-condensate discovery in Angola. Exploratory wells were completed, but without successes, in Niger, Somali Republic, South West Africa, and Spanish Sahara. Eighty-one development wells (solely in Nigeria and Gabon) were completed with 88.8% success. A total of 1,265,201 ft (a new high) of wildcat and development footage was drilled in 1964 in Central and Southern Africa.

376

Petroleum developments in central and southern Africa in 1965  

This review includes 43 countries, i.e., all of Africa except Morocco, Tunisia, Algeria, Libya, Egypt, and Sudan. Total annual production for Central and Southern Africa increased by 93% to 113,604,663 bbl in 1965. This increase was contributed largely by Nigeria, although Gabon also recorded a new high. Production in Congo (Brazzaville) and Angola declined by 15% and 29%, respectively. No other countries produced oil in 1965. Ninety-nine exploratory wells were completed in 1965 (a new record), of which 41% were successful. Thirty-nine oil discoveries were made in Nigeria and 1 in Gabon. One gas discovery was recorded in Gabon. Exploratory wells were completed, but without successes, in Angola, Cameroun, Congo (Leopoldville), Ethiopia, Malagasy Republic, Mozambique, Somali Republic, and Spanish Sahara. One hundred fifteen development wells, solely in Congo (Leopoldville), Nigeria, and Gabon, were completed with 87% success. A total of 1,960,603 ft (a new high) of wildcat and development footage was drilled in 1965 in Central and Southern Africa. At the end of the year, 28 rigs were in operation. Geological-geophysical exploration was greatest in Nigeria.

377

Diverticular disease of the colon in Ibadan, Nigeria.  

Eleven cases of diverticular disease of the colon were seen in a review of 603 adult barium enema examinations carried out over a 2-year period (January 1984-December 1985) at the University College Hospital, Ibadan, Nigeria--a prevalence of 1.85%. All the cases were clinically unsuspected and the d...

378

THE ANALYSIS OF CONFLICT AND NEGOTIATION PROCESS IN NIGERIA AND HUNGARY  

The conclusion reviews that Nigeria and Hungary are similar in terms of the types of Conflict that exist in their organization and in the style they used in resolving Conflict. However, the two countries are different in terms of the causes of Conflicts in their organization, the way they respond an...

379

Governing from Above : Solid Waste Management in Nigeria's New Capital City of Abuja  

This doctoral dissertation examines how the symbolic character of a relocated capital city influences and intersects with local conditions to shape the governance structure and relations in service delivery. The focus is on Abuja, the new capital city of Nigeria, and the sector studied is solid wast...

380

oral history 2 transcript  

program management, and so we had to include them in a lot of our discussions and a lot of our work ..... sure whether it was Nigeria. Kano ..... They said everything had to be program machine language and anything else was a waste of ...

 
 
 
 
381

Determinants of Health Disparities: The Perennial Struggle against Polio in Nigeria  

Polio remains a global public health issue, and even though it has been eradicated from most countries of the world, countries like Nigeria, the largest black nation on earth, threatens the dream of total eradication of polio from the surface of the earth. Transmission of wild polio virus has never ...

382

Bio-remediation of a sludge containing hydrocarbons  

Bio-augmentation has been used as a bio-remediation option for hydrocarbon-contaminated, oily-sludge restoration. This sludge was obtained from the Bonny-Terminal Improvement Project (BTIP) for Bonny Island, near Port Harcourt, Nigeria. Its total hydrocarbon-content (THC) was 69,372 mg/kg of sludge....

383

Water level regulation and control of schistosomiasis transmission: a case study in Oyan Reservoir, Ogun State, Nigeria.  

The effect of different water discharge patterns from the artificial Oyan Reservoir in Ogun State, Nigeria, on water level fluctuations and on schistosomiasis transmission was investigated between August 1990 and March 1993 to determine the impact of water level regulation on schistosomiasis transmi...

384

Ectopic thoracic kidney.  

A case of congenital thoracic kidney recently encountered at the University College Hospital, Ibadan, Nigeria is presented. Ectopic intrathoracic kidney, although very rare, should be considered in any patient with a mass at the base of the lung on a chest radiograph. Intravenous urography is diagno...

385

From rituals to films: a case study of the visual rhetoric of Igbo culture in Nolywood films  

Many reasons have been advanced as to why the video film industry in Nigeria has been so successful financially and in building loyal audiences among Africans around the world. The present thesis argues that Nollywood films help to provide a time and a place for resolving deep-felt tensions in an in...

386

Towards more efficient selection for oil yield in the oil palm (Elaeis guineensis Jacquin)  

Detailed studies are made of the variability and heritability of a number of components of oil yield in the oil palm using published data of the breeding programme of the NIFOR in Nigeria and results of a number of experiments carried out at the OPRC in Ghana during the period 1965-1971. Estimations...

387

Wind of change  

Almost 125MW of wind energy capacity is in operation in the UK, but more rapid progress is needed if it is to meet the Government's target of supplying 10% of electricity demand by 2025. This brief article assesses the situation for developers seeking to capitalise on a still-emerging technology. (Author)

388

Modeling volcanic ash dispersal  

The assessment of volcanic fallout hazard is an important scientific, economic, and political issue, especially in densely populated areas. From a scientific point of view, considerable progress has been made during the last two decades through the use of increasingly powerful computational models and capabilities. Nowadays, models are used to quantify hazard...

389

Detection of Toxin-producing Algae by Low-altitude Remote Sensing Methods  

Methods for detection of freshwater harmful algal blooms have progressed more slowly than those used in marine systems. Techniques for assessment of phytoplankton were applied to catfish aquaculture production ponds. Species capable of producing the algal toxin microcystin were monitored by low-al...

390

Influence of interleukin-1 gene polymorphism on the outcome of supportive periodontal therapy explored by a multi-factorial periodontal risk assessment model (PRA).  

BACKGROUND: Multi-factorial risk models have been proposed to enhance the ability to predict risk for the progression of treated chronic periodontitis. AIMS: to study if the outcomes of supportive periodontal therapy (SPT) based on a multi-factorial periodontal risk assessment are influenced by IL-1...

391

An ecosystem services framework to support both practical conservation and economic development  

The core idea of the Millennium Ecosystem Assessment is that the human condition is tightly linked to environmental condition. This assertion suggests that conservation and development projects should be able to achieve both ecological and social progress without detracting from their primary object...

392

Golgi Calcium Pump Secretory Pathway Calcium ATPase 1 (SPCA1) Is a Key Regulator of Insulin-like Growth Factor Receptor (IGF1R) Processing in the Basal-like Breast Cancer Cell Line MDA-MB-231*  

Calcium signaling is a key regulator of pathways important in tumor progression, such as proliferation and apoptosis. Most studies assessing altered calcium homeostasis in cancer cells have focused on alterations mediated through changes in cytoplasmic free calcium levels. Here, we show that basal-l...

393

Geothermal Progress Monitor. System status and operational experience  

The Geothermal Progress Monitor (GPM) system was designed and implemented by MITRE for DOE's Division of Geothermal Energy (now the Division of Geothermal and Hydropower Technologies). This report summarizes MITRE's operational experience with the system during fiscal year 1983 and provides a qualitative assessment of its data sources.

394

OTEC support services quarterly technical progress report No. 14, 15 August 1981-14 November 1981  

The progress in the areas of system integration, system engineering, and management services is reported. The effort is divided into seven tasks: survey, analysis, and evaluation of technical program status; program technical monitoring; development and implementation of methodology for identification, evaluation, and trade-off for major subsystem configurations; technical assessments; OTEC system integration; environment and siting considerations; and transmission subsystem considerations. (LEW)

395

OTEC support services. Quarterly technical progress report No. 21, 15 May-15 August 1983  

Progress is reported on the system integration, system engineering, and management services for the OTEC program under the following tasks: (1) survey, analysis, and evaluation; (2) program technical monitoring; (3) development and implementation of methodology; (4) technical assessments; (5) OTEC systems integration; (6) environment and siting considerations; and (7) transmission subsystem considerations.

396

OTEC support services quarterly technical progress report No. 15, November 15, 1981-February 14, 1982  

System integration, system engineering, and management services are provided under seven general task areas. These include: survey, analysis, and evaluation of program efforts; program technical monitoring; development and implementation of methodology; technical assessments; OTEC system integration; environment and siting considerations; and transmission subsystem considerations. Each task is briefly described, and technical progress is reported relative to task accomplishments and relative to meetings. (LEW)

397

OTEC support services  

Progress in system integration, system engineering, and management services is reported. The effort is divided into seven tasks: survey, analysis, and evaluation of technical program status; program technical monitoring; development and implementation of methodology for identification, evaluation, and tradeoff for major subsystem configurations; technical assessments; OTEC system integration; environment and siting considerations; and transmission subsystem considerations.

398

A visualization of group cognition: semantic network analysis of a CSCL community  

This paper reports our progress in using the Knowledge Space Visualizer (KSV) as a tool for formative assessment of online discourse. Whereas social network analysis has been used in research on computer-supported collaborative learning, it only examines the social structure of discourse participant...

399

Health and Safety Research Division progress report, April 1, 1981-September 30, 1982  

Research progress for the reporting period is briefly summarized for the following sections: (1) health studies, (2) technology assessments, (3) biological and radiation physics, (4) chemical physics, (5) Office of Risk Analysis, and (6) health and environmental risk and analysis. (ACR)

400

Assessment of indicator gases of spontaneous combustion in underground mines in the Czech Republic Sledování indika?ních plyn? samovznícení v hlubinných dolech ?eské republiky  

Research and applications of findings in the area of early indication of spontaneous combustion of coal using indicator gases started in the Czech Republic in the seventies to eighties of the last century. A significant progress occurred in the second half of the eighties, when methods of assessment...

 
 
 
 
401

Synovitis and osteitis are very frequent in rheumatoid arthritis clinical remission: results from an MRI study of 294 patients in clinical remission or low disease activity state  

In rheumatoid arthritis (RA), radiographic progression may occur despite clinical remission. This may be explained by subclinical inflammation. Magnetic resonance imaging (MRI) provides a greater sensitivity than clinical examination and radiography for assessing disease activity. Our objective was to determine the MRI characteristics of RA patients in clinical remission or low disease activity (LDA) state.

402

Environmental Decision Support with Consistent Metrics  

One of the most effective ways to pursue environmental progress is through the use of consistent metrics within a decision making framework. The US Environmental Protection Agency?s Sustainable Technology Division has developed TRACI, the Tool for the Reduction and Assessment of...

403

Health and Safety Research Division progress report for the period October 1, 1991--March 31, 1993  

This is a progress report from the Health and Safety Research Division of Oak Ridge National Laboratory. Information is presented in the following sections: Assessment Technology, Biological and Radiation Physics, Chemical Physics, Biomedical and Environmental Information Analysis, Risk Analysis, Center for Risk Management, Associate Laboratories for Excellence in Radiation Technology (ALERT), and Contributions to National and Lead Laboratory Programs and Assignments--Environmental Restoration.

404

Clinicopathological Studies on Vitamin D3 Toxicity and Therapeutic Evaluation of Aloe vera in Rats  

A study was conducted to examine the clinical signs, hematological, biochemical and histopathological changes in vitamin D3 toxicity at a dose rate 2 mg/kg b.wt. of vitamin D3 and to assess the protective effect of Aloe vera in vitamin D3 toxicity. The clinical signs observed were anorexia, progress...

405

Progression of rheumatoid arthritis on plain radiographs judged differently by expert radiologists and rheumatologists  

Objective. In a former study a panel of rheumatologists was used to assess which progression in radiological joint damage due to rheumatoid arthritis (RA) on hand and foot radiographs taken at one-year intervals was considered the minimally clinically important difference (MCID). We compare the judg...

406

Quality of survival after severe birth asphyxia.  

Thirty-one children who survived severe birth asphyxia defined by a 1-minute Apgar score of 0, or a 5-minute Apgar score of less than 4, have been seen at age 5 to 10 years for neurological and psychological assessment. Their progress has been compared with that of controls matched for sex, birthwei...

407

In Salah CO2 injection modeling: A preliminary approach to predict short term reservoir behavior  

A short term performance assessment methodology under development and validation at the In Salah CO2 storage site is presented. The progressive approach first concludes of the necessity to consider a dual media reservoir system at Krechba to fit with gas reservoir production, CO2 injection and CO2 b...

408

Telmisartan improves nonalcoholic steatohepatitis in medaka (Oryzias latipes) by reducing macrophage infiltration and fat accumulation  

We investigated the efficacy of the antihypertensive drug telmisartan (Tel) and the mechanisms underlying the progression from simple steatosis to nonalcoholic steatohepatitis (NASH) in a medaka (Oryzias latipes) NASH model. We used the NASH activity score (NAS) developed in humans to assess the his...

409

Contracts for field projects and supporting research on enhanced oil recovery. Progress review quarter ending September 30, 1993  

Progress reports are presented for the following tasks: chemical flooding--supporting research; gas displacement--supporting research; thermal recovery--supporting research; geoscience technology; resource assessment technology; and field demonstrations in high-priority reservoir classes. A list of available publications is also included.

410

Clinical activity and benefit of irinotecan (CPT-11) in patients with colorectal cancer truly resistant to 5-fluorouracil (5-FU)  

The aim of this prospective study was to assess the efficacy, clinical benefit and safety of CPT-11 (irinotecan) in patients with stringently-defined 5-fluorouracil-resistant metastatic colorectal cancer (CRC). 107 patients with documented progression of metastatic CRC during 5-FU were treated with ...

411

A case study of Albania’s participation in PISA 2009  

The paper presents a view of the results and progress of Albania in the Programme for International Students’ Assessments 2009 (PISA 2009). The overall goal and objectives of PISA are to offer support and expertise in the field of the evaluation of educational development factors in Albania. One of ...

412

Urine neopterin: a new parameter for serial monitoring of disease activity in patients with systemic lupus erythematosus.  

OBJECTIVE--To investigate the role of serial measurement of urine neopterin concentration in monitoring the progression of systemic lupus erythematosus (SLE) disease activity scored using the British Isles Lupus Assessment Group (BILAG) index. METHODS--We followed prospectively 68 unselected SLE pat...

413

Prognostication and Risk-Adapted Therapy of Hodgkin's Lymphoma Using Positron Emission Tomography  

The use of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) for response assessment in lymphoma is now widespread. Prognostic information obtained from PET performed after two to three cycles of chemotherapy may guide more individualized, risk-adapted therapeutic strategies. Progress in...

414

Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial  

Patients with follicular lymphoma can have long survival times, but disease progression typically occurs 3-5 years after initial treatment. We assessed the potential benefit of 2 years of rituximab maintenance after first-line treatment in patients with follicular lymphoma receiving a rituximab plus chemotherapy regimen.

415

Method for restoration of normal phenotype in cancer cells  

A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying .beta..sub.1 integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Human breast epithelial cells were shown to be particularly responsive.

416

Restoration of normal phenotype in cancer cells  

A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying .beta..sub.1 integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Human breast epithelial cells were shown to be particularly responsive.

417

Applied nuclear data research and development. Semiannual progress report, April 1-September 30, 1983  

This progress report describes the activities of the Los Alamos Nuclear Data Group for April 1, 1983 through September 30, 1983. Topics covered include theory and evaluation of nuclear cross sections; nuclear cross-section processing and testing; neutron activation; fission products, and actinides; and core neutronics code development in support of LMFBR carbide core assessment. (GHT)

418

Methods for Treating Congestive Heart Failure  

Aug 22, 2003 ... The Merck Manuals Online Medical Library, [online]. Whitehouse .... The Merck Manual of Diagnosis and Therapy, 17th Edition, pp. 1682-1692(1999). ..... Relative severity and disease progression are assessed using well known .... left ventricles of control and aortic stenosis rat hearts. FIGS. 13A and 13B ...

419

WORKSHOP: APPLICATION OF MICROCOSMS FOR ASSESSING THE RISK OF MICROBIAL BIOTECHNOLOGY PRODUCTS  

The U.S. Environmental Protection Agency (EPA) develops testing methods to support assessments of the environmental risks associated with the release of microorganisms and microbial pest control agents. icrocosms may be used as one step in the progression of product development f...

420

Status and scope of technical communication in power supply utilities  

Technical innovations create constantly new possibilities of telecommunication. Power supply utilities alertly follow the progress of this development and regularly assess which forms of communication can be introduced into their networks and which services of the German Post should be adopted. The author describes the available and future potentials and examines their applications in power supply utilities.

 
 
 
 
421

Reclaiming the Future: Space Advocacy and the Idea of Progress  

over the course of american history. this essay assesses how the onset of space ... any people on the face of earth.the key claim of the idea of progress—that ..... apollo” was “the inescapable recognition of the unity and fragility of the earth.” ...

422

PRESENT AND FUTURE OF HIGH ENERGY PHYSICS  

The present status of high-energy physics, and in particular our present knowledge on fundamental particles and their interactions, are critically examined in order to assess what progress can be expected in the future and the role to be played by future European Accelerators.

423

Stochastic hybrid embodied CO2-eq analysis: An application to the Irish apartment building sector  

The development of embodied CO2-eq analysis has progressed significantly in recent years and has become a mainstream practice in many industries as evidenced by the development of the ISO 14040 and 14044 life cycle assessment (LCA) standards. However, it is recognized that due to weaknesses in gathe...

424

The Mixed Waste Management Facility. Monthly report  

Significant progress continued as preliminary design, technical reviews, engineering development, and procurements/contracts moved forward. Key accomplishments were installation and initial operation of the MSO Engineering Development Unit, Peer Review of Analytical Services, development of Preliminary design Baseline guidance, and formal acceptance of the environmental assessment. Budget information on WBS elements are given.

425

Radon in the indoor environment  

The objectives of R and D on radon in the indoor environment at SCK-CEN is to (1) to investigate the deposition of radon progeny in the human respiratory tract by means of direct measurements as a function of aerosol conditions; to assess the radon concentrations in buildings retrospectively with volume traps. Progress and main achievements in 1997 are reported on.

426

D'Hondt, P  

Various aspects related to nuclear fuel are studied at SCK-CEN including the modelling of fission-gas release in LWR fuel, studies on thermal conductivity, investigations on basic physical phenomena, post-irradiation examination for fuel performance assessment, conceptual studies of incidental and accidental fuel studies. Progress and achievements in these areas in 1997 are described.

427

Rheumatoid-susceptible alleles of HLA-DRB1 are genetically recessive to non-susceptible alleles in the progression of bone destruction in the wrists and fingers of patients with RA.  

OBJECTIVE--To assess the relationship between HLA-DRB1 genotypes and the progression of bone destruction in Japanese patients with RA. METHODS--The HLA-DRB1 alleles were determined by polymerase chain reaction and allele specific oligonucleotide probe techniques in 160 Japanese patients with RA. HLA...

428

Re-inspection of small RNA sequence datasets reveals several novel human miRNA genes  

miRNAs are key players in gene expression regulation. To fully understand the complex nature of cellular differentiation or initiation and progression of disease, it is important to assess the expression patterns of as many miRNAs as possible. Thereby, identifying novel miRNAs is an essential prereq...

429

Disruption of Hematopoiesis and Thymopoiesis in the Early Premalignant Stages of Infection with SL3-3 Murine Leukemia Virus  

A time course analysis of SL3-3 murine leukemia virus (SL3) infection in thymus and bone marrow of NIH/Swiss mice was performed to assess changes that occur during the early stages of progression to lymphoma. Virus was detectable in thymocytes, bone marrow, and spleen as early as 1 to 2 weeks postin...

430

Boiling liquid cauldron status report  

The progress made over the past year in assessing the feasibility of the high-temperature, boiling cauldron blanket concept for the tanden mirror reactor is reviewed. The status of the proposed experiments and recently revised estimates of the vapor void fraction in the boiling pool are discussed.

431

Risk-based decisionmaking (Panel)  

By means of a panel discussion and extensive audience interaction, explore the current challenges and progress to date in applying risk considerations to decisionmaking related to low-level waste. This topic is especially timely because of the proposed legislation pertaining to risk-based decisionmaking and because of the increased emphasis placed on radiological performance assessments of low-level waste disposal.

432

Loss of hepatic autoregulation after carbohydrate overfeeding in normal man.  

To determine the effect of increased glycogen stores on hepatic carbohydrate metabolism, 15 nondiabetic volunteers were studied before and after 4 d of progressive overfeeding. Glucose production and gluconeogenesis were assessed with [2-3H] glucose and [6-14C] glucose (Study I, n = 6) or [3-3H] glu...

433

SUSTAINABILITY PLANS FOR THE ACTIVITIES OF THE HEAVY USER COMMUNITIES  

The Heavy User Community activities are planning for a sustainable future – either within their own community, as part of the generic production infrastructure, or through some other mechanism. This report exposes the sustainability plan for each task within the SA3 activity by assessing the progress made to date and by providing plans for 2011.

434

Comparing Selected Measures of Health Outcomes and Health-Seeking Behaviors in Chinese, Cambodian, and Vietnamese Communities of Chicago: Results from Local Health Surveys  

We describe how local community organizations partnered to conduct a survey in the Chinese, Cambodian, and Vietnamese populations of Chicago to compare health outcomes and assess progress toward Healthy People 2010 goals. Interviews were conducted with 380 randomly selected Chinese adults through do...

435

Developments in the clinical understanding of osteoarthritis  

With the recognition that osteoarthritis is a disease of the whole joint, attention has focused increasingly on features in the joint environment which cause ongoing joint damage and are likely sources of pain. This article reviews current ways of assessing osteoarthritis progression and what factor...

436

Stereotactic radiotherapy (radiosurgery) of malignant brain tumors: clinical research; Radiotherapie en conditions stereotaxiques (radiochirurgie) des tumeurs cerebrales malignes: la recherche clinique  

We have looked for trials which are in progress in the field of stereotactic radiotherapy (radiosurgery) of malignant brain tumors. Most randomized trials are conducted by the Radiation Therapy Oncology Group (RTOG) or the European Organization for Research and Treatment of Cancer (EORTC) and assess the role of radiosurgery in treatment of high grade glioma and brain metastasis. (authors)

437

PART I. INTRODUCTION  

The current feasibility of space activities is clearly the product of modern .... Astronautics can provide physical means to aid international inspection and, thereby, .... development versions of Atlas have moved progressively up the range scale as ... In trying to assess the value of a given space effort it is important to recall that ...

438

Re-inspection of small RNA sequence datasets reveals several novel human miRNA genes  

miRNAs are key players in gene expression regulation. To fully understand the complex nature of cellular differentiation or initiation and progression of disease, it is important to assess the expression patterns of as many miRNAs as possible. Thereby, identifying novel miRNAs is an essential prerequisite to make possible a comprehensive and coherent understanding of cellular biology.

439

Naturally fractured tight gas reservoir detection optimization. Quarterly report, April 1--June 30, 1995  

This progress report discusses in details the geologic assessment of the Piceance Creek Basin. Analysis of the high resolution aeromagnetic survey concentrated on the high-resolution aeromagnetic data acquired by World Geoscience, but the interpretation was supplemented by examination of regional published gravity and magnetic data, as well as surface geology and subsurface geology.

440

National Fuel Cell Vehicle Learning Demonstration: Status and Results (Presentation)  

The objectives of this paper are: (1) validate H{sub 2} FC vehicles and infrastructure in parallel; (2) identify current status and evolution of the technology; (3) objectively assess progress toward technology readiness; and (4) provide feedback to H{sub 2} research and development.

 
 
 
 
441

Use of international data sets to evaluate and validate pathway assessment models applicable to exposure and dose reconstruction at DOE Facilities. Progress report, June 1994--September 1994  

The purpose of this work is to evaluate and validate pathway assessment models applicable to exposure and dose reconstruction at DOE facilities through the use of international data sets. This report contains summaries of progress made in the months of June, July, August, and September, 1994.

442

Mud volcanoes in deepwater Nigeria  

Detailed study of 3D seismic data from deepwater Nigeria has revealed the presence of features interpreted to be mud volcanoes. They occur in an upper slope environment seen as 1-2 km circular features at the seabed. Seabed cores from the mud volcanoes contain oil, gas and sand/shale-clast content richer than the seabed background. Pliocene fossils have been identified in the cores, demonstrating transport of material from depth. The features show a high seabed seismic amplitude above a chimney of chaotic seismic reflections and data wipe-out. The mud volcanoes in the study area shows two distinct clusters located over deeper structural culminations. Four active mud volcanoes (Area 1) are located above a rollover anticline in the central part of the area. Cuspate listric faults reach the seabed on the up-slope side of these mud volcanoes. Four abandoned mud volcanoes have also been identified, with progressively older ages towards the crest of the underlying structure. These abandoned features are associated with an extremely chaotic seismic signature. A combination of over-pressured carrier beds and low integrity top seals are believed to be responsible for the formation of these mud volcanoes. It is further believed that gas expansion, subsequent to seal failure, was the main driving force for what must have been violent eruptions. The long lived mud volcano activity over the deep structural closure suggests a plumbing system that focuses on escaping compaction water and hydrocarbons through time. In the south west of the study area, another cluster of five mud volcanoes is located above a shale diapir. The seabed expression of the members of this cluster is more varied. Some show a positive relief at the seabed while others show circular depressions. The largest feature represents an assemblage of many smaller mud volcanoes with a common root system. Their seismic expression is also different from that of Area 1, with a well-defined sediment wedge at surface and a shallower root system. These features are believed to represent a less violent type of mud volcano characterised by ductile flow. Tectonic stress, due to growth of the underlying diapir, is thought to have played an important role during eruption, in addition to focused methane escape and the low mechanical strength of the overburden. (author)

443

Teaching about Homosexualities to Nigerian University Students: A Report from the Field  

Nigeria's diverse cultures, religions and political parties appear to be unified by a strong taboo against homosexuality and gay rights. This has affected academic research, HIV/AIDS programmes, and sexuality education, all which commonly show evidence of heterosexism, self-censorship and even explicit condemnations of homosexuality. Yet a dissident discourse in Nigeria, as well as research from elsewhere in the region, suggests that this appearance of unity may belie greater openness to the issues than assumed. Indeed, research shows that (1) many African societies are traditionally more accommodating toward non-normative sexualities than contemporary nationalist or cultural claims would allow, and (2) secretive "bisexuality" is more common in practice (and tacitly acknowledged) than previously understood. Is it possible then that the presumption of homophobia and the fear of backlash that has clearly contributed to heterosexism and self-censorship in scholarship around homosexualities in Nigeria are exaggerated? Is it possible that Nigerians may be more open to consideration of scientific evidence and international best practices around sexual diversity, rights, and health than is commonly assumed in the literature? A trial intervention at a small state university in a predominantly rural area of Nigeria tested these questions by introducing wide-ranging, frank and non-judgemental (science-based) discussions of same-sex sexuality in several classes. Analysis of the students' feedback finds that stigmatising attitudes toward homosexuality were indeed present among the students. However, there was also a high degree of curiosity, awareness of the existence of secretive homosexualities in Nigeria, desire for education, and confidence that traditional cultures and Nigerian democracy could accommodate individual freedom and sexual rights. The conclusion is that well-prepared researchers and educators could be less anxious and self-censoring around the topic of homosexuality than prevails at present. Careful attention would need to be paid to local sensibilities, but sexuality and HIV education programmes could probably be brought closer into line with world guidelines on best practices and comprehensive approaches to human sexuality education and sexual health. (Contains 13 notes.)

444

Prognostic factors associated with progression of smoldering multiple myeloma to symptomatic form.  

BACKGROUND: Smoldering multiple myeloma (SMM) presents a high risk of progression to symptomatic MM (sy-MM). Herein, we analyzed some predictors of development of sy-MM. In 144 patients with SMM, we also compared the risk of progression predicted by bone marrow plasma cell (BMPC) involvement on the bone marrow biopsy (BMB) versus bone marrow aspirates (BMA). METHODS: From January 1980 to July 2010, 397 patients with SMM observed in 12 centers of the Multiple Myeloma GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) Latium Working Group have been analyzed. At progression to sy-MM, the severity of clinical presentation was graded according to the need of intensive supportive care. RESULTS: After a median follow-up of 135 months, the cumulative incidence of progression rates to sy-MM were 45%, 55%, and 75% at 10, 15, and 20 years, respectively. Hemoglobin ?12.5 g/dL, monoclonal component ?2.5 g/dL, and BMPC ?60% were the only parameters negatively affecting the cumulative incidence of progression. In particular, 10 of 397 (2.5%) patients with BMPC ?60% had a 5.6-fold increased risk of fast progression (within 2 years), which occurred with severe clinical manifestations in 62% of cases. BMB was more sensitive for the detection of BMPC involvement, even though BMA was a more reliable indicator of a rapid progression to sy-MM. CONCLUSIONS: The highest risk of rapid evolution to sy-MM and the severity of clinical manifestation at the progression suggest that SMM patients with a BMPC ?60% should be treated soon after diagnosis. Moreover, BMPC is a more reliable index for progression to sy-MM if assessed by BMA. Cancer 2012. © 2012 American Cancer Society. PMID:22786730

445

Magnetic resonance imaging-determined synovial membrane volume as a marker of disease activity and a predictor of progressive joint destruction in the wrists of patients with rheumatoid arthritis.  

OBJECTIVE: To evaluate the synovial membrane volume, determined by magnetic resonance imaging (MRI), as a marker of joint disease activity and a predictor of progressive joint destruction in rheumatoid arthritis (RA). METHODS: Twenty-six patients with RA, randomized to receive disease-modifying antirheumatic drug (DMARD) therapy alone (11 patients) or DMARDs in combination with oral prednisolone (15 patients), were followed up for 1 year with contrast-enhanced MRI of the dominant wrist (months 0, 3, 6, and 12), conventional radiography (months 0 and 12), and clinical and biochemical examinations. Bone erosion (by MRI and radiography) and synovial membrane volumes (by MRI) were assessed. RESULTS: Significant synovial membrane volume reductions were observed after 3 and 6 months in the DMARD + prednisolone group, and after 6 and 12 months in the DMARD-alone group (P or =10 cm3, erosive progression was found by MRI and/or radiography, indicating a predictive value of synovial membrane volumes. MRI was more sensitive than radiography for the detection of progressive bone destruction (22 versus 12 new bone erosions). CONCLUSION: MRI-determined synovial membrane volumes are closely related to the rate of progressive joint destruction. Quantitative MRI assessment of synovitis may prove valuable as a marker of joint disease activity and a predictor of progressive joint destruction in RA.

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Pilot Projects in Portfolio and Performance-Based Assessment. 1991-1992 Progress Report.  

In 1991 the School District of Philadelphia (Pennsylvania) invited elementary and middle schools to participate in a pilot project to develop and implement portfolio and performance-based assessments. Twenty-five schools began work in winter 1992. Research for Better Schools, Inc. analyzed the progress reports submitted by the schools. The progress reports provided overwhelming support for the pilot and demonstrated enthusiasm and commitment on the part of teachers. The projects marked a move from the teacher as sole evaluator to multiple sources of student evaluation. The approach to instruction began to change as teachers recognized the importance of cooperative learning, peer tutoring, and hands-on projects. School climate was positively affected by the pilot process. Parent participation was influenced by the new forms of assessment and student and parent surveys. Early resistance from some students was being overcome by teacher efforts, although parents were remaining harder to convince about the need for more authentic assessment. An appendix lists participating schools. (SLD)

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Selecting At-Risk First-Grade Readers for Early Intervention: Eliminating False Positives and Exploring the Promise of a Two-Stage Gated Screening Process  

The purposes of this study were (a) to identify measures that when added to a base 1st-grade screening battery help eliminate false positives and (b) to investigate gains in efficiency associated with a 2-stage gated screening procedure. We tested 355 children in the fall of 1st grade and assessed for reading difficulty at the end of 2nd grade. The base screening model included measures of phonemic awareness, rapid naming skill, oral vocabulary, and initial word identification fluency (WIF). Short-term WIF progress monitoring (intercept and slope), dynamic assessment, running records, and oral reading fluency were each considered as an additional screening measure in contrasting models. Results indicated that the addition of WIF progress monitoring and dynamic assessment, but not running records or oral reading fluency, significantly decreased false positives. The 2-stage gated screening process using phonemic decoding efficiency in the 1st stage significantly reduced the number of children requiring the full screening battery. (Contains 9 tables.)

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Natural History of Coronary Atherosclerosis by Multislice Computed Tomography  

Objectives This study sought to analyze the natural history of coronary atherosclerosis by multislice computed tomography (MSCT) and assess the serial changes in coronary plaque burden, lumen dimensions, and arterial remodeling. Background MSCT can comprehensively assess coronary atherosclerosis by combining lumen and plaque size parameters. Methods Thirty-two patients with acute coronary syndromes underwent 64-slice computed tomography angiography after percutaneous coronary intervention at baseline and after a median of 39 months. All patients received contemporary medical treatment. All available coronary segments in every subject were analyzed. The progression of atherosclerosis per segment and per patient was assessed by means of change in percent atheroma volume (PAV), change in norm...

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The occupational impact of sleep quality and insomnia symptoms  

While the importance of assessing the occupational consequences of insomnia is emphasized in clinical nosologies and research guidelines, there is little consensus on which aspects of occupational performance should be assessed, the most methodologically justifiable measures of insomnia and work performance, and how outcomes should be reported. The present review was designed to summarize and methodologically critique the assessment of those aspects of occupational performance most impacted by (or most frequently associated with) insomnia symptoms. The 30 studies which met the review inclusion criteria broadly addressed six domains of occupational functioning: absenteeism; workplace accidents; productivity; punctuality; job satisfaction and career progression. Collectively, study outcomes ...

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