WorldWideScience
 
 
1

Isolation and Purification of Decursin and Decursinol Angelate in Angelica gigas Nakai  

KoreaScience (Korea)

Full Text Available

2009-05-01

2

Cytogenetic Analysis Using Mitosis, Meiosis Chromosomes and bicolor Fluorescence in situ Hybridization of Bupleurum latissimum Nakai  

KoreaScience (Korea)

Full Text Available

2006-12-01

3

Extended amino acid sequences around the active-site lysine residue of class-I fructose 1,6-bisphosphate aldolases from rabbit muscle, sturgeon muscle, trout muscle and ox liver.  

UK PubMed Central (United Kingdom)

1. Amino acid sequences covering the region between residues 173 and 248 [adopting the numbering system proposed by Lai, Nakai & Chang (1974) Science 183, 1204-1206] were derived for trout (Salmo...Full Text Available

1979-11-01

4

MINIMARS: An attractive small tandem mirror fusion reactor  

International Nuclear Information System (INIS)

Through the innovative design of a novel end plug scheme employing octopole MHD stabilization, the authors present the conceptual design of ''MINIMARS'', a small commercial fusion reactor based on the tandem mirror principle. The current baseline for MINIMARS has a net electric output of 600 MWe and they have configured the design for short construction times, factory-built modules, inherently safe blanket systems, and multiplexing in station sizes of #approx =# 600-2400 MWe. They demonstrate that the compact octopole end cell provides a number of advantages over the more conventional quadrupole (yin-yang) end cell encountered in the MARS tandem mirror reactor study, and enables ignition to be achieved with much shorter central cell lengths. Accordingly, being economic in small sizes, MINIMARS provides an attractive alternative to the more conventional larger conceptual fusion reactors encountered to date, and would contribute significantly to the lowering of ...

5

Inverse polynomial optimization  

CERN Document Server

We consider the inverse optimization problem associated with the polynomial program f^*=\\min \\{f(x): x\\in K\\}$ and a given current feasible solution $y\\in K$. We provide a systematic numerical scheme to compute an inverse optimal solution. That is, we compute a polynomial $\\tilde{f}$ (which may be of same degree as $f$ if desired) with the following properties: (a) $y$ is a global minimizer of $\\tilde{f}$ on $K$ with a Putinar's certificate with an a priori degree bound $d$ fixed, and (b), $\\tilde{f}$ minimizes $\\Vert f-\\tilde{f}\\Vert$ (which can be the $\\ell_1$, $\\ell_2$ or $\\ell_\\infty$-norm of the coefficients) over all polynomials with such properties. Computing $\\tilde{f}_d$ reduces to solving a semidefinite program whose optimal value also provides a bound on how far is $f(\\y)$ from the unknown optimal value $f^*$. The size of the semidefinite program can be adapted to the computational capabilities available. Moreover, if one uses the ...

2011-01-01

6

p73 protein regulates DNA damage repair.  

Science.gov (United States)

Although the p53 tumor suppressor is relatively well characterized, much less is known about the functions of other members of the p53 family, p73 and p63. Here, we present evidence that in specific pathological conditions caused by exposure of normal cells to bile acids in acidic conditions, p73 protein plays the predominant role in the DNA damage response. These pathological conditions frequently occur during gastric reflux in the human esophagus and are associated with progression to esophageal adenocarcinoma. We found that despite strong DNA damage induced by bile acid exposure, only p73 (but not p53 and p63) is selectively activated in a c-Abl kinase-dependent manner. The activated p73 protein induces DNA damage repair. Using a human DNA repair PCR array, we identified multiple DNA repair genes affected by p73. Two glycosylases involved in base excision repair, SMUG1 and MUTYH, were characterized and found to be transcriptionally regulated by p73 in DNA damage conditions. Using a ...

2011-09-01