UK PubMed Central (United Kingdom)

Background and purpose:Diphenyleneiodonium (DPI) is often used as an NADPH oxidase inhibitor, but is increasingly being found to have unrelated side effects. We investigated its...Full Text Available

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Abstract Although photosynthetic thermotolerance has been investigated extensively in cotton leaves, reports on the biochemical influence of the pistil in promoting fertilization thermostability are limited. To evaluate the effect of temperature, genotype, and exogenous calcium application on fertilization and pistil biochemistry in cotton, thermosensitive (cv. ST4554 B2RF) and thermotolerant (cv. VH260) plants were grown under control (30/20-C) or high-temperature (38/20-C) conditions during flowering, and exogenous CaCl2 was applied to flowers 1-day prior to anthesis. Measured pistil parameters included fertilization efficiency; protein concentration; glutathione reductase, superoxide dismutase (SOD) and NADPH oxidase activities; and ATP and calcium levels. Exogenous calcium had no effec...

UK PubMed Central (United Kingdom)

Cigarette smoke (CS) induces recruitment of inflammatory cells in the lungs leading to the generation of reactive oxygen species (ROS), which are involved in lung inflammation and injury. Nicotinamide...Full Text Available

UK PubMed Central (United Kingdom)

Increased oxidative stress is a known cause of cardiac dysfunction in animals and patients with diabetes, but the sources of reactive oxygen species [e.g., superoxide anion (O₂⁻)]...Full Text Available

UK PubMed Central (United Kingdom)

Hyperthermia (HT) is a strong adjuvant treatment with radiotherapy and chemotherapy because it causes tumor reoxygenation. However, the detailed molecular mechanisms of how HT enhances tumor oxygenation...Full Text Available

UK PubMed Central (United Kingdom)

NADPH nitrate reductase activity in higher plants has been attributed to the presence of NAD(P)H bispecific nitrate reductases and to the presence of phosphatases capable of hydrolyzing NADPH to NADH....Full Text Available

KoreaScience (Korea)

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Abstract A highly efficient enzyme immobilization method has been developed for electrochemical biosensors using polydopamine films with gold nanoparticles (AuNPs) embedded. This simple enzyme fabrication method can be performed in very mild conditions and stored in a long time with high bioactivity. The fabricated amperometric glucose biosensor exhibited a high and reproducible sensitivity, wide linear dynamic range and low limit of detection (LOD) (0.1 molL-1). A low value of 1.5 mmolL-1 for the apparent Michaelis-Menten constant KappM was obtained. The high sensitivity, wide linear range, good reproducibility and stability make this biosensor a promising candidate for portable amperometric glucose biosensor.

UK PubMed Central (United Kingdom)

We have identified five acyl coenzyme A (CoA) oxidase isozymes (Aox1 through Aox5) in the n-alkane-assimilating yeast Yarrowia lipolytica, encoded by the POX1...Full Text Available

UK PubMed Central (United Kingdom)

An enantio-specific polyphenol oxidase (PPO) was purified ≈1,700-fold to apparent homogeneity from the creosote bush (Larrea tridentata), and its encoding gene was cloned. The...Full Text Available

UK PubMed Central (United Kingdom)

The effects of bivalent cations on cytochrome b5 reduction by NADH:cytochrome b5 reductase and NADPH:cytochrome c reductase were studied with the proteinase-solubilized enzymes. Cytochrome b5 reduction...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

The present study was designed with an aim to analyze the effect of acute aluminium phosphide (ALP) exposure (10mg/kg b.wt, intragastrically) on the kinetic characteristics of cytochrome oxidase and energy metabolism in male Wistar rat liver mitochondria. Liver mitochondrial preparations from ALP-treated rats exhibited significant decrease (66%) in the activity of cytochrome oxidase suggesting that there was a decrease in the catalytic efficiency of the active oxidase molecules on ALP treatment. The decreased activity of cytochrome oxidase with altered NADH and succinic dehydrogenase activities might have contributed towards a significant decline in state 3 and state 4 respiration as observed. These alterations in the electron transport chain complexes in turn adversely affected the ATP sy...

UK PubMed Central (United Kingdom)

Mechanism-based inhibition of cytochrome P450 (CYP) 3A4 is characterized by NADPH-, time-, and concentration-dependent enzyme inactivation, occurring when some drugs are converted by CYPs to reactive...Full Text Available

UK PubMed Central (United Kingdom)

The effects of antimalarials, chloroquine and quinacrine, on the generation of reactive oxygen species were examined both in polymorphonuclear leucocytes and in the xanthine-xanthine oxidase system....Full Text Available

UK PubMed Central (United Kingdom)

The effect of the polyamine oxidase (PAO)-polyamine system on some helminths was examined in vitro. Both Schistosoma mansoni schistosomula and Dirofilaria immitis microfilariae were highly sensitive...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Rat lung and liver microsomes did not undergo lipid peroxidation in the absence of iron when incubated with NADPH and concentrations of paraquat ranging from 10/sup -7/ to 10/sup -2/ M. Paraquat also did not stimulate rat liver and lung microsomal peroxidation induced by added iron and NADPH, and was inhibitory at concentrations above 10 ..mu..M. Similarly, no stimulation of peroxidation was produced by paraquat in rabbit or human lung microsomes; however, under similar conditions, paraquat enhanced NADPH/iron-dependent peroxidation in mouse lung and liver microsomes obtained from rats sacrificed at 12, 18, and 24 hr following a lethal dose of paraquat (50 mg/kg, ip), there was no loss of vitamin E or increase in susceptibility to in vitro peroxidation which would be expected if lipid peroxidation had occurred in vivo although extensive lung damage developed during this time period. These results indicate that paraquat does ...

UK PubMed Central (United Kingdom)

The phylogeny and taxonomy of mammalian species were originally based upon shared or derived morphological characteristics. However, genetic analyses have more recently played an increasingly important...Full Text Available

UK PubMed Central (United Kingdom)

The concentration of indoleacetic acid (IAA) in plant tissues is regulated, in part, by its rate of decarboxylation. However, the commonly used in vitro assays for IAA oxidase may not...Full Text Available

UK PubMed Central (United Kingdom)

Sesquiterpene lactones are characteristic natural products in Asteraceae, which constitutes ∼8% of all plant species. Despite their physiological and pharmaceutical importance, the biochemistry...Full Text Available

UK PubMed Central (United Kingdom)

The flacca tomato (Lycopersicon esculentum) mutant displays a wilty phenotype as a result of abscisic acid (ABA) deficiency. The Mo cofactor (MoCo)-containing aldehyde...Full Text Available

UK PubMed Central (United Kingdom)

Observations made during biochemical and toxicological studies of the housefly, in which the WHO standard reference (SR) strain was used as a standard, indicated that this strain differs from other...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Here we examine Fe speciation within Fe-encrusted biofilms formed during 2-month seafloor incubations of sulfide mineral assemblages at the Main Endeavor Segment of the Juan de Fuca Ridge. The biofilms were distributed heterogeneously across the surface of the incubated sulfide and composed primarily of particles with a twisted stalk morphology resembling those produced by some aerobic Fe-oxidizing microorganisms. Our objectives were to determine the form of biofilm-associated Fe, and identify the sulfide minerals associated with microbial growth. We used micro-focused synchrotron-radiation X-ray fluorescence mapping (mu XRF), X-ray absorption spectroscopy (mu EXAFS), and X-ray diffraction (mu XRD) in conjunction with focused ion beam (FIB) sectioning, and highresolution transmission electron microscopy (HRTEM). The chemical and mineralogical composition of an Fe-encrusted biofilm was queried at different spatial scales, and the spatial relationship between primary sulfide and ...

British Library Electronic Table of Contents (United Kingdom)

We quantified the resistance levels of transgenic rice plants, expressing Myxococcus xanthus protoporphyrinogen oxidase (PROTOX) in chloroplasts and mitochondria, to PROTOX inhibitors, acifluorfen, oxyfluorfen, carfentrazone-ethyl, and oxadiazon. We also determined whether active oxygen species-scavenging enzymes are involved in the resistance mechanism of transgenic rice. The transgenic rice line M4 was about >200-fold more resistant to oxyfluorfen than the wild-type (WT). M4 was also resistant to acifluorfen, carfentrazone-ethyl, and oxadiazon, but did not show multiple resistance to imazapyr and paraquat, which have different target sites. Acifluorfen, oxyfluorfen, carfentrazone-ethyl, and oxadiazon reduced the chlorophyll content in leaves of WT, but had minimal or no effect on M4. The...

Energy Technology Data Exchange (ETDEWEB)

Trihydroxynaphthalene reductase catalyzes two intermediate steps in the fungal melanin biosynthetic pathway. The enzyme, a typical short-chain dehydrogenase, is the biochemical target of three commercial fungicides. The fungicides bind preferentially to the NADPH form of the enzyme. Three X-ray structures of the Magnaporthe grisea enzyme complexed with NADPH and two commercial and one experimental fungicide were determined at 1.7 {angstrom} (pyroquilon), 2.0 {angstrom} (2,3-dihydro-4-nitro-1H-inden-1-one, 1), and 2.1 {angstrom} (phthalide) resolutions. The chemically distinct inhibitors occupy similar space within the enzyme's active site. The three inhibitors share hydrogen bonds with the side chain hydroxyls of Ser-164 and Tyr-178 via a carbonyl oxygen (pyroquilon and 1) or via a carbonyl oxygen and a ring oxygen (phthalide). Active site residues occupy similar positions among the three structures. A buried water molecule that is ...

UK PubMed Central (United Kingdom)

Bovine microvascular endothelial cells (MEC) were able to degrade the H2O2 generated by phorbol myristate acetate-activated bovine neutrophils or by glucose oxidase with a maximal capacity of 4.0 +/-...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

2-methylpropan-1-ol (isobutanol) is a leading candidate biofuel for the replacement or supplementation of current fossil fuels. Recent work has demonstrated glucose to isobutanol conversion through a modified amino acid pathway in a recombinant organism. Although anaerobic conditions are required for an economically competitive process, only aerobic isobutanol production has been feasible due to an imbalance in cofactor utilization. Two of the pathway enzymes, ketol-acid reductoisomerase and alcohol dehydrogenase, require nicotinamide dinucleotide phosphate (NADPH); glycolysis, however, produces only nicotinamide dinucleotide (NADH). Here, we compare two solutions to this imbalance problem: (1) over-expression of pyridine nucleotide transhydrogenase PntAB and (2) construction of an NADH-de...

Energy Technology Data Exchange (ETDEWEB)

Sheep red blood cells (SRBCs) were labelled with a concanavalin A-luminol-bovine serum albumin conjugate specific for the transmembrane anion transport protein (Band 3) and exposed to 2450-MHz continuous-wave microwave radiation at an average specific absorption rate of 91W/kg for 10 min. The temperature was held constant at 25, 37, 40, 42, or 45C with an airflow heat-exchange system. Following exposure to microwave or air heating, the decrease in residual base-activated chemiluminescence (CL) of the SRBCs was measured as an indication of infield oxidase activity. Air heating resulted in a significant decrease in residual CL at temperatures above 37C (74% decrease at 45C). Microwave radiation inhibited the decline in residual CL above 37C. At 45C the inhibition was 40%. The results suggest microwave radiation either reversibly altered the thermodynamics of oxygen binding to haemoglobin or failed to energize a significant portion of the haemoglobin molecules in each ...

British Library Electronic Table of Contents (United Kingdom)

In Indian traditional medicine, various plants have been used widely as a remedy for treating snakebites. The aim of this study was to evaluate the effect of Tamarindus indica seed extract on the pharmacological as well as the enzymatic effects induced by V. russelli venom. Tamarind seed extract inhibited the PLA2, protease, hyaluronidase, L-amino acid oxidase and 5prime-nucleotidase enzyme activities of venom in a dose-dependent manner. These are the major hydrolytic enzymes responsible for the early effects of envenomation, such as local tissue damage, inflammation and hypotension. Furthermore, the extract neutralized the degradation of the Bb chain of human fibrinogen and indirect hemolysis caused by venom. It was also observed that the extract exerted a moderate effect on the clotting ...

British Library Electronic Table of Contents (United Kingdom)

Rosas-Valdez, R., Choudhury, A. & Prez-Ponce de Len, G. (2011). Molecular prospecting for cryptic species in Phyllodistomum lacustri (Platyhelminthes, Gorgoderidae). -Zoologica Scripta, 40, 296-305. Partial sequences of the 28S ribosomal RNA and cytochrome c oxidase I (COI) genes were compared among populations of a widely distributed and morphologically uniform digenean species in North America, Phyllodistomum lacustri, a parasite characteristically associated with ictalurid catfishes. Specimens were collected from the urinary bladder of ictalurid hosts in six localities of North America, spanning most of the latitudinal range of this freshwater fish group. Sequences of other congeneric species, including a potentially close relative, P.-staffordi, were also obtained and used for comparis...

British Library Electronic Table of Contents (United Kingdom)

Abstract The benthic marine worm Xenoturbella is frequently contaminated with molluscan DNA, which had earlier caused confusion resulting in a suggested bivalve relationship. In order to find the source of the contaminant, we have used molluscan sequences derived from Xenoturbella and compared them to barcodes obtained from several individuals of the nonmicroscopic molluscs sharing the same environment as Xenoturbella. Using cytochrome oxidase 1, we found the contaminating sequences to be 98% similar to the bivalve Ennucula tenuis. Using the highly variable D1-D2 region of the large ribosomal subunit in Xenoturbella, we found three distinct species of contaminating molluscs, one of which is 99% similar to the bivalve Abra nitida, one of the most abundant bivalves in the Gullmarsfjord where...

UK PubMed Central (United Kingdom)

We investigated nutrient limitations during hydrocarbon degradation in a sandy soil and found that fixed nitrogen was initially a limiting nutrient but that N limitation could sometimes be overcome...Full Text Available

KoreaScience (Korea)

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Science.gov (United States)

In this work, we query the Chlamydomonas reinhardtii copper regulon at a whole-genome level. Our RNA-Seq data simulation and analysis pipeline validated a 2-fold cutoff and 10 RPKM (reads per kilobase of mappable length per million mapped reads) (~1 mRNA per cell) to reveal 63 CRR1 targets plus another 86 copper-responsive genes. Proteomic and immunoblot analyses captured 25% of the corresponding proteins, whose abundance was also dependent on copper nutrition, validating transcriptional regulation as a major control mechanism for copper signaling in Chlamydomonas. The impact of copper deficiency on the expression of several O2-dependent enzymes included steps in lipid modification pathways. Quantitative lipid profiles indicated increased polyunsaturation of fatty acids on thylakoid membrane digalactosyldiglycerides, indicating a global impact of copper deficiency on the photosynthetic apparatus. Discovery of a putative plastid copper chaperone and a membrane protease in the thylakoid ...

Science.gov (United States)

We presented a simple approach for in-situ synthesis of poly(dimethylsiloxane) (PDMS)-gold nanoparticles composite film based on the special characteristics of PDMS itself. It is an environmentally safe synthesis method without the requirement of additional reducing/stabilizing agents. The region where the resulting gold nanoparticles distribute (in the matrix or on the surface of the polymer) and the size of the nanoparticles, as well as the colour of the free-standing films, can be simply controlled by adjusting the ratio of curing agent and the PDMS monomer. The chemical and optical properties of these composite films were studied. Using such a method, gold nanoparticle micropatterns on PDMS surfaces can be performed. And based on the gold nanoparticles micropattern, further modification with antibodies, antigens, enzymes and other biomolecules can be achieved. To verify this ability, an immobilized glucose oxidase (GOx) reactor in microchannels was built and ...

KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

This paper identifies some of the issues which arise in the consideration of the derivation of new limits on exposure to internal emitters. Basic and secondary radiation protection limits are discussed. Terms are defined and applied to the limitation of risk from stochastic effects. Non-stochastic data for specific internal emitters (/sup 131/I and the radium isotopes) are presented. Emphasis is placed on the quantitative aspects of the limit setting problem. 65 references, 2 figures, 12 tables.

Energy Technology Data Exchange (ETDEWEB)

The performance of a gas-fuelled diesel engine (dual fuel) is examined at light load and an effective threshold limit to the combustion of the gaseous fuel through bulk flame spread is identified. The relationship of such a limit to some of the key operating parameters is then discussed. A comparison between the measured values of the limit with those corresponding to the lower flammability limits of the gaseous fuel when evaluated under the prevailing cylinder conditions during pilot diesel fuel ignition showed similar trends. It is suggested that such a similarity may form a basis for estimating the lean operation limits for duel a fuel combustion in engines. A simple approach for estimating the limiting equivalence ratio for the apparent bulk flame spread limit is described for a methane-fuelled dual fuel engine. (Author)

KoreaScience (Korea)

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Science.gov (United States)

... significantly lower limits of detection. The complex fluorescence spectra of these constructs indicated that only a portion ...

Science.gov (United States)

... Attributes and limitations of the charac- terization framework are illustrated through comparison with experimental PLZT data. ...

Energy Technology Data Exchange (ETDEWEB)

We report an analysis of four strains of baker's yeast (Saccharomyces cerevisiae) using biocavity laser spectroscopy. The four strains are grouped in two pairs (wild type and altered), in which one strain differs genetically at a single locus, affecting mitochondrial function. In one pair, the wild-type rho+ and a rho0 strain differ by complete removal of mitochondrial DNA (mtDNA). In the second pair, the wild-type rho+ and a rho- strain differ by knock-out of the nuclear gene encoding Cox4, an essential subunit of cytochrome c oxidase. The biocavity laser is used to measure the biophysical optic parameter Deltalambda, a laser wavelength shift relating to the optical density of cell or mitochondria that uniquely reflects its size and biomolecular composition. As such, Deltalambda is a powerful parameter that rapidly interrogates the biomolecular state of single cells and mitochondria. Wild-type cells and mitochondria produce Gaussian-like distributions ...

Science.gov (United States)

Influenza virus infection during pregnancy has been implicated as one of cause of premature delivery, abortion and stillbirth. We have reported that cultured human fetal membrane chorion cells undergoing apoptosis by influenza virus infection secrete unidentified heat-stable monocyte differentiation-inducing (MDI) factors. In this study, cellular, biological and immunochemical characteristics of MDI factors were investigated using human monocytic leukemia THP-1 cells by nitroblue tetrazolium reduction and cell adhesion assays. The treatment of THP-1 cells with culture supernatants from the influenza virus-infected chorion cells induced the nitroblue tetrazolium reduction ability, which was inhibited by the addition of superoxide dismutase and diphenyleneiodonium chloride, an inhibitor for reduced nicotinamide adenine dinucleotide phosphate oxidase. The phenomenon was also observed in human peripheral blood monocytes and histiocytic leukemia U937 cells, but not in ...

Energy Technology Data Exchange (ETDEWEB)

A database has been developed to contain the disposal limits for the E-Area Low Level Waste Facility (ELLWF). This database originates in the form of an EXCEL{copyright} workbook. The pertinent sheets are translated to PDF format using Adobe ACROBAT{copyright}. The PDF version of the database is accessible from the Solid Waste Division web page on SHRINE. In addition to containing the various disposal unit limits, the database also contains hyperlinks to the original references for all limits. It is anticipated that database will be revised each time there is an addition, deletion or revision of any of the ELLWF radionuclide disposal limits.

Energy Technology Data Exchange (ETDEWEB)

The physics of density limit phenomena in toroidal helical plasmas based on an analytic point model of toroidal plasmas is discussed. The combined mechanism of the transport and radiation loss of energy is analyzed, and the achievable density is derived. A scaling law of the density limit is discussed. The dependence of the critical density on the heating power, magnetic field, plasma size and safety factor in the case of L-mode energy confinement is explained. The dynamic evolution of the plasma energy and radiation loss is discussed. Assuming a simple model of density evolution, of a sudden loss of density if the temperature becomes lower than critical value, then a limit cycle oscillation is shown to occur. A condition that divides the limit cycle oscillation and the complete radiation collapse is discussed. This model seems to explain the density limit oscillation that has been ...

Science.gov (United States)

Our long-term goal is to enable highly productive plant species to extract, resist, detoxify, and/or sequester toxic heavy metal pollutants as an environmentally friendly alternative to physical remediation methods. We have focused this phytoremediation research on soil and water-borne ionic and methylmercury. Mercury pollution is a serious world-wide problem affecting the health of human and wild-life populations. Methylmercury, produced by native bacteria at mercury-contaminated wetland sites, is a particularly serious problem due to its extreme toxicity and efficient biomagnification in the food chain. We engineered several plant species (e.g., Arabidopsis, tobacco, canola, yellow poplar, rice) to express the bacterial genes, merB and/or merA, under the control of plant regulatory sequences. These transgenic plants acquired remarkable properties for mercury remediation. (1) Transgenic plants expressing merB (organomercury lyase) extract methylmercury from their growth substrate and ...

UK PubMed Central (United Kingdom)

G-protein-coupled receptor signalling has been suggested to be voltage dependent in a number of cell types; however, the limits of sensitivity of this potentially important phenomenon are unknown. Using...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundIn a world limited by data availability and limited funds for conservation, scientists and practitioners must use indicator groups to define spatial conservation priorities....Full Text Available

UK PubMed Central (United Kingdom)

Nutrient transport affinities of nutrient-starved microbial populations were measured as initial slopes of plots of limiting-nutrient transport rates versus extracellular limiting-nutrient concentrations....Full Text Available

Science.gov (United States)

This report estimates the economic and financial effects of compliance with the proposed effluent limitations guidelines and standards for the Centralized Waste Treatment (CWT) industry. The Environmental Protection Agency (EPA) has measured these impacts...

Science.gov (United States)

This section presents background information supporting the development of effluent limitations guidelines and standards for the concentrated aquatic animal production (CAAP) point source category. Section 1.1 presents the legal authority to regulate the ...

Science.gov (United States)

This document presents regulations and research support the EPA`s effluent limitations for the paving and roofing materials point source category.

Science.gov (United States)

This analysis, submitted in support of proposed effluent limitations guidelines and standards for the centralized waste treatment (CWT) industry, investigates the cost-effectiveness of 24 regulatory options, representing all possible combinations of nine ...

UK PubMed Central (United Kingdom)

BackgroundObtaining single parasite clones is required for many techniques in malaria research. Cloning by limiting dilution using microscopy-based assessment for parasite growth...Full Text Available

Science.gov (United States)

... Development Document for Proposed Effluent Limitations Guidelines and Standards for the Shipbuilding and Repair Point Source Category (Draft ...

International Nuclear Information System (INIS)

Object: To limit the discharge amount of reactor water in a primary system at the time of scram to prevent excessive outflow of reactor water outside the system. Structure: A signal from an upper limit position indicator detects the fact that control rods are completely inserted when the reactor is urgently stopped and the detection signal causes a valve in an outflow line of the discharge water from a control rod driving mechanism to be closed to limit the amount of discharge flown into the scram discharge vessel, thus preventing outflow of reactor water in the primary system after the scram has been initiated. (Kamimura, M.).

CERN Document Server

We give a general local central limit theorem for the sum of two independent random variables, one of which satisfies a central limit theorem while the other satisfies a local central limit theorem with the same order variance. We apply this result to various quantities arising in stochastic geometry, including: size of the largest component for percolation on a box; number of components, number of edges, or number of isolated points, for random geometric graphs; covered volume for germ-grain coverage models; number of accepted points for finite-input random sequential adsorption; sum of nearest-neighbour distances for a random sample from a continuous multidimensional distribution.

Science.gov (United States)

No abstract available.

Science.gov (United States)

... populations ..... 63 34 Vertebral ultimate compressive strength for various populations ..... 64 35 ...

Science.gov (United States)

Snake envenomation employs three well integrated strategies: prey immobilization via hypotension, prey immobilization via paralysis, and prey digestion. Purines (adenosine, guanosine and inosine) evidently play a central role in the envenomation strategies of most advanced snakes. Purines constitute the perfect multifunctional toxins, participating simultaneously in all three envenomation strategies. Because they are endogenous regulatory compounds in all vertebrates, it is impossible for any prey organism to develop resistance to them. Purine generation from endogenous precursors in the prey explains the presence of many hitherto unexplained enzyme activities in snake venoms: 5'-nucleotidase, endonucleases (including ribonuclease), phosphodiesterase, ATPase, ADPase, phosphomonoesterase, and NADase. Phospholipases A(2), cytotoxins, myotoxins, and heparinase also participate in purine liberation, in addition to their better known functions. Adenosine contributes to prey immobilization ...

Energy Technology Data Exchange (ETDEWEB)

In a reactor environment, the surface of a limiter or wall is primarily determined by the mechanism of erosion and deposition of surface material. It should be possible to use pellet injection to reduce net erosion to zero everywhere if low-Z materials are used for the surface. Erosion rates can, in general, be minimized by large area limiters and high plasma temperatures, which transmit power to the walls with less sputtering. Under ideal steady state conditions the wall surface is dominated by metallurgical effects in the wall.

International Nuclear Information System (INIS)

The EPA proposed effluent limitations guidelines and standards for the offshore segment of the oil and gas industry on August 26, 1985. On November 26, 1990, and March 13, 1991, the Agency reproposed effluent limitations guidelines and standards for both drilling and production wastes. The report is primarily concerned with the total annualized cost incurred by the offshore oil and gas industry in complying with the regulations.

International Nuclear Information System (INIS)

This paper addresses known limitations and constraints in eddy current nondestructive testing. Incomplete appreciation for eddy current limitations is believed to have contributed to both under-utilization and misapplication of the technique. Neither situation need arise if known limitations are recognized. Some, such as the skin depth effect, are inherent to electromagnetic test methods and define the role of eddy current testing. Others can be overcome with available technology such as surface probes to find circumferential cracks in tubes and magnetic saturation of ferromagnetic alloys to eliminate permeability effects. The variables responsible for limitations in eddy current testing are discussed and where alternative approaches exist, these are presented. Areas with potential for further research and development are also identified.

Energy Technology Data Exchange (ETDEWEB)

The phenomenon of the limit of pitting corrosion in direction to positive potentials is studied by potentiokinetic polarization after a jump in the transpassive range and by potentiostatic tests at technical wrought materials and at model alloys of the systems NiCrMo and NiMo in CaCl{sub 2} solution in the concentration range 1 to 9 mol/l chloride at pH-values of 1 to 9 at temperatures of 30 to 110 C. Surface-analytical investigations gives in connection with knowledges from anodic polarization studies directions to the mechanism of the limit of pitting corrosion. Ranges of the limit of pitting corrosion are obtained at materials with a Mo content above 6.5% and contents of chloride of the media above 2 mol/l chloride. Increasing temperatures, increasing contents of chloride and sulfate shift the potential of the limit of pitting corrosion being always above 0.2 V (SCE) at potentiostatic determination ...

International Nuclear Information System (INIS)

We report on a promising approach to high-sensitivity anisotropy measurements using a high-finesse cavity locked by optical feedback to a diode laser. We provide a simple and effective way to decouple the weak anisotropy of interest from the inherent mirror's birefringence whose drift may be identified as the key limiting parameter in cavity-based techniques. We demonstrate a shot-noise-limited phase shift resolution previously inaccessible in an optical cavity, readily achieving the state-of-the-art level of 3x10"-"1"3 rad.

Energy Technology Data Exchange (ETDEWEB)

An improved ion funnel design is disclosed that decreases the axial RF (parasite) fields at the ion funnel exit. This is achieved by addition of one or more compensation electrodes after the conductance limit electrode. Various RF voltage profiles may be applied to the various electrodes minimizing the parasite axial potential wells. The smallest RF aperture that serves as the conductance limiting electrode is further reduced over standard designs. Overall, the ion funnel improves transmission ranges of both low m/z and high m/z ions, reducing RF activation of ions and decreasing the gas load to subsequent differential pumping stages.

Energy Technology Data Exchange (ETDEWEB)

Fractal dimensional analysis was employed to obtain a quantitative measure of the morphology of polymer networks formed by UV irradiation induced polymerization of photo-reactive mesogenic monomers dissolved in a liquid crystal host medium. The fractal dimensions obtained, may be interpreted by polymer network growth following a percolation-like model for monomer concentrations well below the solubility limit. On passing the solubility limit, the polymerization process changes from a (radical chain) solution polymerization to a dispersion polymerization, with fractal dimensions decreasing and suggesting a cluster-cluster aggregation process for monomer concentrations above the solubility limit, similar to the aggregation of colloidal particles.

Energy Technology Data Exchange (ETDEWEB)

Technical Development Document supporting proposed water discharge regulations for the Coal Mining Industry authorized by the Clean Water Act. Proposed regulations include revised best practicable technology limitations, best available technology limitations and new source performance standards for the Coal Mining Industry. Industry operations include: coal preparation and amillary operations, active mining, F bituminous, anthracite and lignite coal, and the reclamation phase of mining.

Medline Plus

[music] Narrator: New treatments can limit the disability caused by a stroke, but you need to know the signs and act in time. Here are the signs to ...

Science.gov (United States)

... to light-light a laser or directed energy weapon would ... space-based components... .the most likely threats are direct ascent anti-satellite weapons; ...

UK PubMed Central (United Kingdom)

BackgroundABCA3 transporter (ATP-binding cassette transporter of the A subfamily) is localized to the limiting...Full Text Available

International Nuclear Information System (INIS)

... Fuel Limited, Reprocessing Business Division, Rokkasho, Aomori (Japan)

UK PubMed Central (United Kingdom)

Statistical fluctuations limit the precision with which a microorganism can, in a given time T, determine the concentration of a chemoattractant in the surrounding medium. The best a cell can do is...Full Text Available

Science.gov (United States)

These include, but are not limited to: stellar winds and outflows, post-main- sequence stellar evolution, binary/multiple star evolution, globular cluster ...

Wastenet

be extremely limited or even negative due to higher maritime transport costs leading to a modal shift back to

Energy Technology Data Exchange (ETDEWEB)

The operational limits of the Tower Shielding Reactor-2 (TSR-2) have been revised to account for placing the reactor in a beam shield, which reduces convection cooling during a loss-of-coolant accident (LOCA). A detailed heat transfer analysis was performed to set operating time limits which preclude fuel damage during a LOCA. Since a LOCA is survivable, the pressure boundary need not be safety related, minimizing seismic and inspection requirements. Measurements of reactor component emittance for this analysis revealed that aluminum oxidized in water may have emittance much higher than accepted values, allowing higher operating limits than were originally expected. These limits could be increased further with analytical or hardware improvements. 5 refs., 7 figs.

Energy Technology Data Exchange (ETDEWEB)

A nonneutral /sup 7/Li/sup +/ ion plasma is described in which ion Langmuir waves are observed for the first time. The properties of these waves near the Brillouin density limit are investigated.

International Nuclear Information System (INIS)

In the revised GCFR Safety Program Plan a quantitative risk limit line has been adopted to establish requirements for the safety related functions and systems. The risk limit line is derived from an interpretation of NRC established licensing requirements, including those for LMFBR's. Multiple barriers to the progression of accident sequences are defined in the form of six Lines of Protection (LOPs). LOPs-1 to 3 are dedicated to accident prevention and represent the normal operating systems, the dedicated safety systems and the inherent design features, respectively. LOPs-4 to 6 are dedicated to the mitigation of core melt accident consequences and include in-vessel accident containment, secondary containment integrity and radiological attenuation, respectively. Cumulative frequency limits and consequence limits are established for each LOP. Design features associated with each LOP are described and the ...

Science.gov (United States)

These include, but are not limited to: stellar winds and outflows, post-main- sequence stellar evolution, binary/multiple star evolution, globular cluster structure ...

UK PubMed Central (United Kingdom)

Background and objectives: Despite potential significance of fatigue and its underlying components in the occurrence of cardiovascular diseases, epidemiologic data showing the link are virtually limited....Full Text Available

Science.gov (United States)

Sep 3, 2010 ... These higher-quality deformable mirrors will enable diffraction-limited performance for many space-based optical systems such as space-based ...

Science.gov (United States)

No abstract available.

Energy Technology Data Exchange (ETDEWEB)

This standard specifies requirements for the flameproofing and the limiting of surface temperature and exhaust emission control of diesel engine systems for use in underground coal mines.

UK PubMed Central (United Kingdom)

Due to the use of a limited number of species and subchronic exposures, current ecological hazard assessment processes can underestimate the chronic toxicity of environmental contaminants resulting...Full Text Available

Science.gov (United States)

... of North American Wild Sheep, Desert Bighorn Council, Asarco Limited Liability Corporation, Pima County, Arizona Desert Bighorn ... ...

Science.gov (United States)

airborne separation assistance systems (ASAS) to ... operations should be limited to the outer traffic flow ...... AGARD Meeting on Machine Intelligence in Air ...

UK PubMed Central (United Kingdom)

BackgroundHearing loss is a common sensory disorder, yet prospective data on potentially modifiable risk factors are limited. Regularly used analgesics, the most...Full Text Available

International Nuclear Information System (INIS)

A new evaluation of the 1% time strain limit for creep strength and the isochronous stress/strain relationship was to be undertaken for the type 800 alloy, based on up to date experimental data. After the evaluation of the 1% time strain limit curves and time fracture curves of individual melts, multilinear regression analyses were made to clear up the relationship between parameters of the creep behaviour such as creep strength, 1% time strain limit and time fracture strain on the one hand and metallurgical parameters such as C, Ti, Al, Ni, Cr contents or grain size and type of manufacture, on the other hand. Based on the knowledge gained from these calculations, new limits were determined for HTR material specifications for variants of the 800 alloy of the Rk, NT, DE, and HT type. (orig./DG).

Science.gov (United States)

... HAL and VAL limits with the specified PMD of 10-7, the GPS range-rate error must be monitored to assure that the inertial navigation error is not ...

Energy Technology Data Exchange (ETDEWEB)

This paper is concerned with methods of limiting the build-up of transient voltages between sheath and armor in long armored power cables. Calculations by a frequency dependent cable model demonstrate that this voltage can be efficiently limited to an acceptable level by introducing sheath-armor bondings at regular intervals, or by using a semiconductive sheath-armor interlayer. The paper investigates the required minimum length between bondings, as well as the required conductivity of the sheath-armor interlayer if the use of bondings is to be avoided.

Energy Technology Data Exchange (ETDEWEB)

Environmental exposure measurements are, in general, positive and may be subject to left censoring; i.e,. the measured value is less than a ''detection limit''. In occupational monitoring, strategies for assessing workplace exposures typically focus on the mean exposure level or the probability that any measurement exceeds a limit. Parametric methods used to determine acceptable levels of exposure, are often based on a two parameter lognormal distribution. The mean exposure level, an upper percentile, and the exceedance fraction are used to characterize exposure levels, and confidence limits are used to describe the uncertainty in these estimates. Statistical methods for random samples (without non-detects) from the lognormal distribution are well known for each of these situations. In this report, methods for estimating these quantities based on the maximum likelihood method for randomly ...

Environmental Research Database

DescriptionAbstract of Research Proposal The root environment has a major effect on crop growth, both directly through the supply of water and nutrients to the shoot, and indirectly through root to shoot signalling. Better management of crop root systems through agronomic and genetic means has the potential to improve the efficiency of water and nutrient uptake, and limit root restrictions to crop growth. However, progress in this area is currently limited by the lack of sensors for in situ estimates of [continued...

International Nuclear Information System (INIS)

Overcoming the limiting constraints of stimulated Raman scattering (SRS) and stimulated Brilluoin scattering (SBS) poses serious fibre design challenges for increasing the output power of optical amplifiers and lasers. New fibre amplifier designs are proposed to break out of these limitations to reach several kWs CW powers. (Author)

CERN Document Server

We prove a uniqueness result for limit cycles of the second order ODE $\\ddot x + \\sum_{j=1}^{J}f_{j}(x)\\dot x^{j} + g(x) = 0$. We extend a uniqueness result proved in \\cite{CRV}. The main tool applied is an extension of Massera theorem proved in \\cite{GS}.

Energy Technology Data Exchange (ETDEWEB)

In our previous theoretical analyses, solubility-limited mass transfer from waste solids applies if a species is at a constant elemental concentration in liquid at the waste surface. For an element with isotopes that decay appreciably during the time of interest, a solubility boundary condition results in a time-dependent boundary concentration of each isotope. Here we present mass-transfer equations that include the effects of isotopic decay boundary conditions. 9 refs., 1 fig.

Energy Technology Data Exchange (ETDEWEB)

The Focused-Ion-Beam (FIB) is a powerful tool for fast, precision cross-sectioning and inspection of submicron defects in multilayered integrated circuit devices. However, the low contrast between the layers in FIB cross-sections can make the feature of interest difficult to observe, which has become a limitation for FIB cross-sectioning. A technique using plasma etch to decorate the FIB cross-sections has proven to be a simple solution to overcome this limitation.

Energy Technology Data Exchange (ETDEWEB)

Various methods have been proposed to condition an electron beam in order to reduce its emittance effect and to improve the short-wavelength free electron laser (FEL) performance. In this paper, we show that beam conditioning does not result in a complete elimination of the emittance effect in an alternating-gradient focusing FEL undulator. Using a one-dimensional model and a three-dimensional simulation code, we derive a criteria for the emittance limitation of a perfectly conditioned beam that depends on the focusing structure.

Energy Technology Data Exchange (ETDEWEB)

The purpose of the study is to analyze the economic impact which could result from the application of effluent limitations guidelines and standards issued under Sections 301, 304, 306, 307, 308, and 501 of the Clean Water Act to the plastics molding and forming industry.

Energy Technology Data Exchange (ETDEWEB)

Contents of this report are under the following topical sections: Legal Authority; Summary and Scope; Data Collection Activities; Industry Description; Industry Subcategorization; Water Use and Wastewater Characterization; Pollutants Selected for Regulation; Pollution Prevention and Wastewater Treatment Technologies; Development of Control and Treatment Options; Costs of Technology Bases for Regulations; Pollutant Reduction Estimates; Non-Water Quality Impacts; Implementation of Proposed Effluent Limitation Guidelines and Standards; Analytical Methods; and Glossary.

Science.gov (United States)

This document presents the findings of a study of the Ink Manufacturing Industry for the purpose of developing effluent limitations and standards, and pretreatment standards for existing and new sources to implement Sections 301, 304, 306, 307 and 501 of ...

Energy Technology Data Exchange (ETDEWEB)

The document reports the results of a cost-effectiveness analysis of alternative water pollution control regulations of the battery manufacturing industry. These regulations include effluent limitations and standards based on best practical control technology currently available, best available technology economically achievable, and pretreatment standards for new sources. For each of these regulations, EPA has identified several pollution control options, each with different levels of pollution abatement and compliance cost. The analysis is a tool for evaluating the options.

International Nuclear Information System (INIS)

We present a method for obtaining the quasi-exact solutions of the Rabi Hamiltonian in the framework of the asymptotic iteration method (AIM). The energy eigenvalues, the eigenfunctions and the associated Bender-Dunne orthogonal polynomials are deduced. We show (i) that orthogonal polynomials are generated from the upper limit (i.e., truncation limit) of polynomial solutions deduced from AIM, and (ii) prove to have nonpositive norm. (authors)

International Nuclear Information System (INIS)

Combustion noise, knock and ignition limits data are measured and presented for a dual fuel engine running on dual fuels of Diesel and three gaseous fuels separately. The gaseous fuels used are liquefied petroleum gas, pure methane and compressed natural gas mixture. The maximum pressure rise rate during combustion is presented as a measure of combustion noise, and the knocking and ignition limits are presented as torque output at the onset of knocking and ignition failure. Experimental investigation on the dual fuel engine revealed the noise generated from combustion, knocking and ignition limits for all gases at different design and operating conditions. A Ricardo E6 Diesel version engine is converted to run on dual fuel of Diesel and the tested gaseous fuel and is used throughout the work. The engine is fully computerized, and the cylinder pressure data, crank angle data and engine operating variables are stored in a PC ...

Energy Technology Data Exchange (ETDEWEB)

There are two kinds of uncertainties in safety assessment of engineering structures. One is of the nature of randomness, and the other fuzziness. Fuzzy uncertainties exist in defining certain structural performances, conditions, parameters, and their interrelationships. The theory of fuzzy sets should be employed to cope with the fuzzy uncertainties. In this paper, a general definition for structural failure considering the fuzzy uncertainties is introduced firstly. Failure of the structure is modelled by a fuzzy event, and described by the membership function. The limit state surface is then replaced by a fuzzy limit state zone, in which every point represents a state belonging to the failure with a certain degree of membership. Then a fuzzy optimization problem for solving the reliability index is formulated. In classical structural reliability theory, the reliability index is defined by the minimum distance from the ...

International Nuclear Information System (INIS)

Ball screw bearings are used for the fine control of Control Rod Drive Mechanism (CEDM) for the SMART-P. Because the friction coefficient of the ball screw bearings suddenly increases at the limit temperature of 120 .deg. C, the surrounding temperature of the ball screw bearings should be less than the limit temperature for the functional integrity of the CEDM. The CEDM coolers are installed at the lower portion of the ball screw bearings to maintain the bearings' temperature less than the limit. In order to check the CEDM cooler satisfy the temperature limit of ball screw bearing at the possible operational conditions, the cooling capacity of the CEDM coolers, which was determined at the stage of 'conceptual design', is evaluated using the Computational Fluid Dynamics(CFD) code, Fluent. The analysis result shows that the current CEDM coolers satisfy the CEDM temperature limit of ...

International Nuclear Information System (INIS)

The difficult economic circumstances with which almost the whole world had to contend, brought serious financial crisis in many countries. South Africa also had its own share of serious problems. Despite this situation, Transvaal Consolidated Land and Exploration Company, Limited, showed on increase in earnings of 24 per cent per share. The reason for this lies mainly in two areas. Firstly the company acquired the mining related business of Rand Mines, Limited. Included in the acquisition was a partfolio of shares mainly in the company's associated gold and uranium mining companies and additional shares in its listed coal mining subsidiaries. Secondly, the average gold price realised by producers in rand terms, was considerably higher than in the previous year. Consolidated profit attributable to members increased by 52 per cent to R82,6 million.

British Library Electronic Table of Contents (United Kingdom)

Political leaders in numerous nations argue for an upper limit of the global average surface temperature of 2 K above the pre-industrial level, in order to attempt to avoid the most serious impacts of climate change. This paper analyzes what this limit implies in terms of radiative forcing, emissions pathways and abatement costs, for a range of assumptions on rate of ocean heat uptake and climate sensitivity. The primary aim is to analyze the importance of ocean heat uptake for radiative forcing pathways that temporarily overshoot the long-run stabilization forcing, yet keep the temperature increase at or below the 2 K limit. In order to generate such pathways, an integrated climate-economy model, MiMiC, is used, in which the emissions pathways generated represent the least-cost solution o...

Energy Technology Data Exchange (ETDEWEB)

TOXCHEM is a microcomputer based modelling system for predicting the fate of toxic contaminants in wastewater treatment plants. The package evaluates concentrations of toxics in final effluent and waste sludge, and mass air emissions from municipal or industrial activated sludge wastewater treatment plants. Maximum allowable influent concentrations of toxics required to meet effluent discharge or air emission limits can also be estimated. The package contains a read-only database with treatability parameters for over 100 contaminants, including organic compounds and metals. If effluent or sludge quality limits have been specified, treatment plant owners and operators can use the package to estimate the permissable discharge limits for dischargers to their collection system. A hypothetical example is provided of application of the software to a planning problem involving the start up of a new operation that would discharge ...

British Library Electronic Table of Contents (United Kingdom)

Theory predicts trade-offs between investment in various life history traits, and it is also now generally accepted that reproduction is costly for males. Males must therefore optimize resource allocation across several episodes of reproduction, and this includes investment in both pre- and postcopulatory fitness components. We investigated this in the sperm-polymorphic Indian meal moth, Plodia interpunctella. Resource-limited males were smaller, and had decreased precopulatory mating success, measured as lifetime number of matings. However, they transferred similar numbers of fertile sperm as males reared under high-quality larval conditions, and more nonfertile sperm. By mating less frequently, resource-limited males may allocate sufficient resources to the matings they achieve to ensure...

International Nuclear Information System (INIS)

Ozone is a principal component of photochemical air pollution endogenous to numerous metropolitan areas. It is primarily formed by the oxidation of NOx in the presence of sunlight and reactive organic compounds. Ozone is a highly active oxidizing agent capable of causing injury to the lung. Lung injury may take the form of irritant effects on the respiratory tract that impair pulmonary function and result in subjective symptoms of respiratory discomfort. These symptoms include, but are not limited to, cough and shortness of breath, and they can limit exercise performance. The effects of ozone observed in humans have been primarily limited to alterations in respiratory function, and a range of respiratory physiological parameters have been measured as a function of ozone exposure in adults and children. These affects have been observed under widely varying (clinical experimental and environmental settings) conditions

International Nuclear Information System (INIS)

The highest equilibrium free-carrier doping concentration possible in a given material is limited by the ''pinning energy'' which shows a remarkable universal alignment in each class of semiconductors. Our first-principles total energy calculations reveal that equilibrium n -type doping is ultimately limited by the spontaneous formation of close-shell acceptor defects: the 3- -charged cation vacancy in AlN, GaN, InP, and GaAs and the 1- -charged DX center in AlAs, AlP, and GaP. This explains the alignment of the pinning energies and predicts the maximum equilibrium doping levels in different materials. (c) 2000 The American Physical Society

British Library Electronic Table of Contents (United Kingdom)

In mobile animals, movement behavior can maximize fitness by optimizing access to critical resources and minimizing risk of predation. We sought to evaluate several hypotheses regarding the effects of landscape structure on American marten foraging path selection in a landscape experiencing forest perforation by patchcut logging. We hypothesized that in the uncut pre-treatment landscape marten would choose foraging paths to maximize access to cover types that support the highest density of prey. In contrast, in the post-treatment landscapes we hypothesized marten would choose paths primarily to avoid crossing openings, and that this would limit their ability to optimally select paths to maximize foraging success. Our limiting factor analysis shows that different resistant models may be sup...

International Nuclear Information System (INIS)

A large detector with high redundancy is used to search for various types of anomalous particles in cosmic rays at sea level. The detector is sensitive to zenith angles between 45"0 and 90"0. Previously obtained limits on the fluxes of charge (1/3) and (2/3) particles are reduced to 2.9 x 10"-"1"0 and 2.6 x 10"-"1"0 cm"-"2sr "-"1 sec"-"1, respectively. The flux of ionizing tachyons is determined to be less than 2.4 x 10"-"9 cm"-"2 sr"-"1 sec"-"1. The massive-particle flux limit we obtain is inconsistent with previous claims of such particles assuming that these particles are isotropic in zenith angle.

Science.gov (United States)

This report estimates the economic and financial effects and the benefits of compliance with the proposed effluent limitations guidelines and standards for the Centralized Waste Treatment (CWT) industry. The Environmental Protection Agency (EPA) has measured these impacts in terms of changes in the profitability of waste treatment operations at CWT facilities, changes in market prices to CWT services, and changes in the quantities of waste management at CWT facilities in six geographic regions. EPA has also examined the impacts on companies owning CWT facilities (including impacts on small entities), on communities in which CWT facilities are located, and on environmental justice. EPA examined the benefits to society of the CWT effluent limitations guidelines and standards by examining cancer and non-cancer health effects of the regulation, recreational benefits, and cost savings to publicly owned treatment works (POTWs) to which ...

British Library Electronic Table of Contents (United Kingdom)

Abstract Aim- Two alternative hypotheses attempt to explain the upper elevation limit of tree lines world-wide, the carbon-limitation hypothesis (CLH) and the growth-limitation hypothesis (GLH); the altitudinal decrease of temperature is considered the driver constraining either carbon gain or growth. Using a widely distributed tree line species (Nothofagus pumilio) we tested whether tree line altitude is explained by the CLH or the GLH, distinguishing local from global effects. We elaborated expectations based on most probable trends of carbon charging with altitude according to both hypotheses, considering the alternative effects of drought. Location- Two climatically contrasting tree line ecotones in the southern Andes of Chile: Mediterranean (3654- S) and Patagonia (4604- S). Methods- ...

Science.gov (United States)

The purpose of this rulemaking is to amend the effluent limitations guidelines and standards for the control of discharges of certain pollutants associated with the use of synthetic-based drilling fluids (SBFs) and other non-aqueous drilling fluids in portions of the Offshore Subcategory and Cook Inlet portion of the Coastal Subcategory of the Oil and Gas Extraction Point Source Category. These proposed limitations apply to discharges or effluent generated when oil and gas wells are drilled using SBFs or other non-aqueous drilling fluids (collectively referred to simply as SBFs) in coastal and offshore regions in locations where drilling wastes may be discharged.

International Nuclear Information System (INIS)

Containment is considered as ultimate safety system and is designed to enclose whole reactor system and prevent the spread of active air-borne fission products. For Pressure and Temperature calculation, Design Basis Accident (Dba) is double ended break of reactor inlet header or main steam line break but activity release studies are done to access its performance following limiting design basis accident i.e. Loss of Coolant Accident (LOCA) and Emergency Core Cooling System (ECCS). In such accident scenario, the core is severely damaged and results in production of steam and hydrogen along with release of activity to containment environment. Containment functions are maintained in such accident, and radiological consequences are within the prescribed limits. (author)

International Nuclear Information System (INIS)

The thermal recovery of superconducting elements working as secondaries in fault current limiters can be enhanced by taking advantage of the removal of heat by conduction from an array of artificial weak zones (AWZ) distributed along the superconductor perimeter (hot parts) to the non-weak segments (cold parts). These results were obtained by studying samples with weak parts in the shape of grooves, all identical in size. In this paper we consider the case in which one of the AWZ is slightly different from the rest. Our results show that a change in its length has a negligible effect. On the contrary, a groove which is slightly deeper can be overheated and hence can strongly determine the recovery time of the whole limiter.

UK PubMed Central (United Kingdom)

The side effects of cancer therapy on normal tissues limit the success of therapy. Generation of reactive oxygen species (ROS) has been implicated for numerous chemotherapeutic agents including doxorubicin...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Power output of a hydrogen-diesel dual-fuel engine is limited by the onset of knock as the percentage of heat input derived from hydrogen increased beyond a certain limit. Earlier work carried out at the Internal Combustion Engines Laboratory, Indian Institute of Technology, Madras, indicates that this knock sets in when the induced hydrogen exceeds about 60% of input energy at a pilot diesel quantity of 30% of full load diesel amount. At higher rates of hydrogen induction, the richer hydrogen-air mixture is more prone to knocking. Hardly any information is available on the possibilities of improving the knock limited power output of a hydrogen-diesel dual-fuel engine. Water can serve as a powerful internal coolant in decreasing the unburned mixture temperature because of its high latent heat. This paper presents the results of our investigation on improving the knock limited power output when water is ...

UK PubMed Central (United Kingdom)

The rapid global loss of natural habitats and biodiversity, and limited resources, place a premium on maximizing the expected benefits of conservation actions. The scarcity of information on the fine-grained...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A formula and technology are presented for the preparation of a hydrolyzed polyacrylonitrile (gipane) from the wastes of chemical production, analysis of the results of working to use them to insulate influxes of water in the extracting wells of the Sokolovogorskiy field.

UK PubMed Central (United Kingdom)

Depleted uranium (DU) is a dense heavy metal used primarily in military applications. Although the health effects of occupational uranium exposure are well known, limited data exist regarding the long-term...Full Text Available

UK PubMed Central (United Kingdom)

Recent research has implicated the nucleus accumbens (NAc) in consolidating recently acquired goal-directed appetitive memories, including spatial learning and other instrumental processes. However,...Full Text Available

UK PubMed Central (United Kingdom)

1. At high running speeds, the step frequency becomes lower than the apparent natural frequency of the body's bouncing system. This is due to a relative increase of the vertical component of the muscular...Full Text Available

UK PubMed Central (United Kingdom)

Most of the general population is exposed to carbaryl and other contemporary-use insecticides at low levels. Studies of laboratory animals, in addition to limited human data, show an association between...Full Text Available

UK PubMed Central (United Kingdom)

Objectives. We assessed the effectiveness of various systems of community participation in ethical review of environmental health research.Methods. We used situation...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundCharacterizing infectious disease burden in Africa is important for prioritizing and targeting limited resources for curative and preventive services and monitoring the...Full Text Available

UK PubMed Central (United Kingdom)

Microbes in nature frequently function as members of complex multitaxon communities, but the structural organization of these communities at the micrometer level is poorly understood because of limitations...Full Text Available

UK PubMed Central (United Kingdom)

Background:Encouragement of stroke patients to resume driving is important to promote their reintegration into the community. Limited rehabilitation has been performed in this regard,...Full Text Available

UK PubMed Central (United Kingdom)

This paper discusses the fundamentals, applications, potential, limitations, and future perspectives of polarized light reflection techniques for the characterization of materials and related systems...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundCurrently used indicators of iron status have limitations. Hepcidin, a key regulator of iron metabolism, is reduced in iron deficiency. We sought to determine the properties...Full Text Available

UK PubMed Central (United Kingdom)

Angiosarcoma (AS) is a rare and aggressive vascular neoplasm with very poor prognosis. Patients with extensive cutaneous AS who are not surgical candidates have very limited options since there is no...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This report discusses the following topics: Fusion-fission in light nuclear systems; High-resolution Q-value measurement for the {sup 24}Mg+{sup 24}Mg reaction; Heavy-ion reactions and limits to fusion; and Hybrid MWPC-Bragg curve detector development.

UK PubMed Central (United Kingdom)

ObjectiveLimited data is available to understand the prevalence and correlates of suicidal behavior among U.S. Latino subgroups. This paper compares the prevalence...Full Text Available

UK PubMed Central (United Kingdom)

Previous studies with a limited number of strains have indicated that there are two genotypes of yellow fever (YF) virus in Africa, one in west Africa and the other in east and central Africa. We have...Full Text Available

UK PubMed Central (United Kingdom)

The pharmacokinetics of oral fluoroquinolone antibiotics in normal volunteers have been studied extensively; however, limited patient data exist. Enoxacin steady-state pharmacokinetics and bioavailability...Full Text Available

UK PubMed Central (United Kingdom)

Acetaminophen (APAP) toxicity is the most common drug-induced cause of acute liver failure in the United States. The only available treatment, N-acetylcysteine (NAC), has a limited...Full Text Available

UK PubMed Central (United Kingdom)

Development of mouse models representing human spontaneous ovarian cancer has been hampered by the lack of understanding of the etiology of this very complex disease. Mouse models representing the different...Full Text Available

UK PubMed Central (United Kingdom)

The use of percutaneous transluminal coronary angioplasty is limited by procedural complications and the serious drawback of restenosis, but some new techniques have been developed in an attempt to...Full Text Available

UK PubMed Central (United Kingdom)

Wild-type viruses from the ViroLogic phenotype-genotype database were evaluated to determine the upper confidence limit of the drug susceptibility distributions, or “biological cutoffs,”...Full Text Available

UK PubMed Central (United Kingdom)

We showed recently that secretion of glutamate in biotin-limited cells of Corynebacterium glutamicum is mediated by carrier systems in the plasma membrane (C. Hoischen and R. Krämer, Arch. Microbiol....Full Text Available

Energy Technology Data Exchange (ETDEWEB)

We investigate terms with four derivatives in the low-energy action of closed Bose strings. Our analysis is consistent with the possibility that the action involves only curvatures of an affine connection with torsion. The torsion is provided by the antisymmetric tensor gauge field.

UK PubMed Central (United Kingdom)

BackgroundThe widespread use of nutritional supplements among athletes is poorly understood. The prevalence of supplement intake and users' knowledge have been researched independently...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundRecent research highlights the promise of remotely sensed aerosol optical depth (AOD) as a proxy for ground-level particulate matter with aerodynamic diameter ≤...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundIntegration of medical care across clinicians and settings could enhance the quality of care for patients. To date, there is limited data on the levels of integration in...Full Text Available

UK PubMed Central (United Kingdom)

Peptic ulcer bleeding is a common disease and recurrent bleeding is an independent risk factor of mortality. Infusion with proton pump inhibitors (PPIs) prevents recurrent bleeding after successful...Full Text Available

UK PubMed Central (United Kingdom)

Infection due to multidrug resistance pathogens is difficult to manage due to bacterial virulence factors and because of a relatively limited choice of antimicrobial agents. Thus, it is imperative to...Full Text Available

UK PubMed Central (United Kingdom)

The effectiveness of chemotherapy in human schistosomiasis varies from one area to another, and limited data from experimentally infected animals suggest inherent differences in the susceptibility...Full Text Available

UK PubMed Central (United Kingdom)

Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic...Full Text Available

UK PubMed Central (United Kingdom)

Noise pollution from human traffic networks and industrial activity impacts vast areas of our planet. While anthropogenic noise effects on animal communication are well documented, we have very limited...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This paper describes effects of methods to calculate and analyze bearing capacities and transformation of pile foundations in the limit state design method. Different pile bearing capacity estimating expressions including criteria used in other countries were applied to the case of steel piles driven into the `diatomaceous mudstone ground` in Noto Peninsula, Ishikawa Prefecture where detailed ground and soil surveys have been made, and the case of piles driven in place into the `sandy and clayish soil alternating ground layers` at the Tennoji area in Osaka Prefecture. The results were compared with those of static loading tests. As a result, the estimated bearing capacity limit was found to agree relatively well with the measured values where uniaxial compression strength was used according to the reference architectural formula. The estimated bearing capacity limit using the N-value as the soil constant has underestimated ...

UK PubMed Central (United Kingdom)

The computational fluid dynamics methods for the limited flow rate and the small dimensions of an intracranial artery stenosis may help demonstrate the stroke mechanism in intracranial atherosclerosis....Full Text Available

International Nuclear Information System (INIS)

This article examines the effects of competition of geothermal energy production with other technologies. The topics of the article include near-term market growth, cause for cautious optimism, limits to development of geothermal energy production, economic arguments for development of geothermal power plants, the effects of a competitive market on industry survival.

UK PubMed Central (United Kingdom)

Recently, there has been significant progress in the development of genetically-engineered mouse (GEM) models. By introducing genetic alterations and/or signaling alterations of human pancreatic cancer...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A prototype detector based on the inclined absorber layer principle is introduced. For the Liquids Reflectometer at the Spallation Neutron Source, it is shown to be a significant improvement over its current detector, which imposes an instantaneous count rate limitation of 50 kcps.

UK PubMed Central (United Kingdom)

Parasitic nematodes cause serious diseases in humans, animals, and plants. They have limited lipid metabolism and are reliant on lipid-binding proteins to acquire these metabolites from their hosts....Full Text Available

UK PubMed Central (United Kingdom)

BackgroundCyclooxygenase (cox) is the rate-limiting enzyme, which catalyzes the conversion of arachidonic acid into prostaglandins and contributes to the inflammatory process. Cyclooxygenase-2...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Role-limiting approaches support knowledge acquisition (KA) by centering knowledge base construction on common types of tasks or domain-independent problem-solving strategies. Within a particular problem-solving strategy, domain-dependent knowledge plays specific roles. A KA tool then helps a user to fill these roles. Although role-limiting approaches are useful for guiding KA, they are limited because they only support users in filling knowledge roles that have been built in by the designers of the KA system. EXPECT takes a different approach to KA by representing problem-solving knowledge explicitly, and deriving from the current knowledge base the knowledge gaps that must be resolved by the user during KA. This paper contrasts role-limiting approaches and EXPECT`s approach, using the propose-and-revise strategy as an example. EXPECT not only supports users in filling knowledge roles, but also ...

UK PubMed Central (United Kingdom)

The incidence of melanoma is increasing more than any other cancer, and knowledge of its genetic alterations is limited. To systematically analyze such alterations, we performed whole-exome...Full Text Available

UK PubMed Central (United Kingdom)

Alternatives for developing chronic exposure limits for noncancer effects of trichloroethylene (TCE) were evaluated. These alternatives were organized within a framework for dose-response assessment--exposure:dosimetry...Full Text Available

UK PubMed Central (United Kingdom)

A quantum computer (QC) can operate in parallel on all its possible inputs at once, but the amount of information that can be extracted from the result is limited by the phenomenon of wave function...Full Text Available

CERN Document Server

A pedagogical introduction to the equivalence theorem for longitudinal vector bosons in electroweak theories is given and the problem of tree-level unitarity at high energies in models of electroweak interactions is briefly reviewed. To make the treatment self-containded, the basic of the Standard Model are summarized in an appendix.

UK PubMed Central (United Kingdom)

By using EPR measurements of radiation-induced radicals it is possible to utilize human fingernails to estimate radiation dose after-the-fact. One of the potentially limiting factors in this...Full Text Available

UK PubMed Central (United Kingdom)

Energetically costly behaviours, such as flight, push physiological systems to their limits requiring metabolic rates (MR) that are highly elevated above the resting MR (RMR). Both RMR and MR during...Full Text Available

UK PubMed Central (United Kingdom)

The recovery of schistosome cercariae from natural waters has been limited by variations in turbidity and in the accuracy of recovery with different techniques. A modification of the Rowan vacuum paper...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Cited are the results of physico-chemical studies and industrial tests of a copolymer of methacrylic acid and diethylammonium salt, used for limiting the influx of stratum waters into a well.

UK PubMed Central (United Kingdom)

Improved NMR detection of mass limited samples can be obtained by taking advantage of the mass sensitivity of microcoil NMR, while throughput issues can be addressed using multiple, parallel...Full Text Available

UK PubMed Central (United Kingdom)

Recently reported technologies for DNA-directed organic synthesis and for DNA computing rely on routing DNA populations through complex networks. The reduction of these ideas to practice has been limited...Full Text Available

Science.gov (United States)

The report analyzes the cost-effectiveness of two alternative regulatory options: A Treated Discharge Option and a Zero Discharge Option. The report compares the total annualized cost incurred for each of the two regulatory options to the corresponding ef...

Science.gov (United States)

This study investigates the contributions of the military working dogs in Vietnam to determine their significance to the United States' war effort. There is limited written history concerning the use of the military working dogs in Vietnam. The methods an...

UK PubMed Central (United Kingdom)

There is limited information about the true incidence of acute renal failure (ARF). Most studies could not quantify disease frequency in the general population as they are hospital-based and...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundUntil now only limited research has been done on the prevalence of chronic pain in primary care. The aim of this investigation was to study the health care utilisation...Full Text Available

UK PubMed Central (United Kingdom)

Hookworms, bloodfeeding intestinal nematodes, infect nearly one billion people in resource limited countries and are a leading cause of anemia and malnutrition. Like other nematodes, hookworms...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

An unexpectedly high probability of collisions between the fission particles and the atoms in an ionization chamber along the entire particle track causes a strong fluctuation of the shapes of the Bragg curves. This fluctuation imposes an upper limit of the charge resolution ..delta..Z/Z which can be achieved.

UK PubMed Central (United Kingdom)

BackgroundOceans are iron-deficient and nutrient-poor environments. These conditions impart limitations on our understanding of and our ability to identify microorganisms from the...Full Text Available

Science.gov (United States)

Record production of heavy water was achieved: the plants at Glace Bay and Port Hawkesbury, Nova Scotia, produced a total of 560 megagrams. A shipment of 500 Mg was delivered on time to the Wolsung CANDU reactor in Korea. Energy conservation and waste hea...

UK PubMed Central (United Kingdom)

BackgroundThe Gram-negative, xylem-limited phytopathogenic bacterium Xylella fastidiosa is responsible for causing economically important diseases in grapevine,...Full Text Available

CERN Document Server

We present space-based photometry of the transiting exoplanetary system HD 209458 obtained with the MOST (Microvariablity and Oscillations of STars) satellite, spanning 14 days and covering 4 transits and 4 secondary eclipses. The HD 209458 photometry was obtained in MOST's lower-precision Direct Imaging mode, which is used for targets in the brightness range $6.5 < V < 13$. We describe the photometric reduction techniques for this mode of observing, in particular the corrections for stray Earthshine. We do not detect the secondary eclipse in the MOST data, to a limit in depth of 0.053 mmag (1 \\sigma). We set a 1 \\sigma upper limit on the planet-star flux ratio of 4.88 x 10^-5 corresponding to a geometric albedo upper limit in the MOST bandpass (400 to 700 nm) of 0.25. The corresponding numbers at the 3 \\sigma level are 1.34 x 10^-4 and 0.68 respectively. HD 209458b is half as bright as Jupiter in the MOST ...

UK PubMed Central (United Kingdom)

BackgroundWith rates of childhood obesity increasing, physical activity (PA) promotion especially in young children has assumed greater importance. Given the limited effectiveness...Full Text Available

UK PubMed Central (United Kingdom)

Transthyretin aggregation-associated proteotoxicity appears to cause several human amyloid diseases. Rate-limiting tetramer dissociation and monomer misfolding of transthyretin (TTR) occur before...Full Text Available

UK PubMed Central (United Kingdom)

Background and AimsSecondary growth via successive cambia has been intriguing researchers for decades. Insight into the mechanism of growth layer formation is, however, limited to...Full Text Available

Science.gov (United States)

...f) Are there additional requirements that must be met? (1) A person subject to this section must: (i) For fuel oils and liquid fuels, obtain, record, and keep records of the percent sulfur by weight from the vendor for each...

DEFF Research Database (Denmark)

Several enzymes of the metabolic pathways responsible for metabolism of cytosolic ribonucleotides and deoxyribonucleotides are located in mitochondria. Studies described in this paper suggest dysfunction of the mitochondria to affect these metabolic pathways and limit the available levels of cytosolic ribonucleotides and deoxyribonucleotides, which in turn can result in aberrant RNA and DNA synthesis. Mitochondrial dysfunction has been linked to genomic instability, and it is possible that the limiting effect of mitochondrial dysfunction on the levels of nucleotides and resulting aberrant RNA and DNA synthesis in part can be responsible for this link. This paper summarizes the parts of the metabolic pathways responsible for nucleotide metabolism that can be affected by mitochondrial dysfunction.

International Nuclear Information System (INIS)

The structure functions (SF) of nuclei determined within the framework of the flucton model with rescaling (FMR) are compared with new experimental data of the ITEP on cumulative #pi#-meson yield in a wide range of the scale variable X (1limiting fragmentation is verified. It is shown that the agreement between theoretical calculations for SF nuclei ratios obtained in analysis of deep inelastic lepton scattering by nuclei within the FMR framework and experimental data on #pi#"+-meson production on Be, Al, Cu, Ta nuclei in cumulative region has confirmed the hypothesis of limiting fragmentation.

Energy Technology Data Exchange (ETDEWEB)

Health physicists from the Brookhaven National Laboratory (BNL) visited the Savannah River Site (SRS) as one of 12 facilities operated by the Department of Energy (DOE) contractors with annual collective dose equivalents greater than 100 person-rem (100 person-cSv). Their charter was to review, evaluate and summarize as low as reasonably achievable (ALARA) techniques, methods and practices as implemented. This presentation gives an overview of the two selected ALARA practices implemented at the SRS: Administrative Exposure Limits and Goal Setting. These dose control methods are used to assure that individual and collective occupational doses are ALARA and within regulatory limits.

Science.gov (United States)

The results of a study conducted by Working Group 10 of the AGARD Fluid Dynamics Panel to investigate the limits of boundary layer methods, both the integral and field type formulations, for calculating three-dimensional turbulent separated flow are presented. Test cases used to assess the boundary layer calculations included the DFLVR prolate spheroid at angle of attack and the NASA-Ames Wing C. Comparisons between boundary layer calculations and experimental data are presented for these test cases along with observations, conclusions, and recommendations.

Energy Technology Data Exchange (ETDEWEB)

Smooth and notched specimens of the bearing steel 100Cr6 (SAE 52100) in a bainitic condition were used to determine the S-N-curves under tensile, torsional and combined in- and out-of-phase loading. In the area of high-cycle-fatigue, crack initiation was most likely caused by inclusions like Titanium Carbonitrides or Aluminium Oxides. A model was developed to describe the influence of the magnitude of these inclusions on the lifetime. A weakest link model, using the statistical distribution of inclusions and surface flaws, was used to describe the fatigue limit. (orig.)

Energy Technology Data Exchange (ETDEWEB)

The restricted temperature stability of the synthetic thermal oil which is used as heat carrier fluid in parabolic trough collectors so far limits the live steam parameters in the steam cycle to approximately 375 Celsius. In order to break through this limit, already for quite some time it is researched to replace the thermal oil by boiler feeding waters and to accomplish the evaporation in the collectors. The contribution under consideration gives an overview on the direct evaporation concept and summarizes the past operational experiences. Moreover, the challenges with the integration of this technology in a steam turbine cycle are elaborated.

CERN Document Server

This paper introduces a new parsimonious structure for mixture of autoregressive models. the weighting coefficients are determined through latent random variables, following a hidden Markov model. We propose a dynamic programming algorithm for the application of forecasting. We also derive the limiting behavior of unconditional first moment of the process and an appropriate upper bound for the limiting value of the variance. This can be considered as long run behavior of the process. Finally we show convergence and stability of the second moment. Further, we illustrate the efficacy of the proposed model by simulation and forecasting.

Energy Technology Data Exchange (ETDEWEB)

An energy control strategy (10) for a hybrid electric vehicle that controls an electric motor during bleed and charge modes of operation. The control strategy (10) establishes (12) a value of the power level at which the battery is to be charged. The power level is used to calculate (14) the torque to be commanded to the electric motor. The strategy (10) of the present invention identifies a transition region (22) for the electric motor's operation that is bounded by upper and lower speed limits. According to the present invention, the desired torque is calculated by applying equations to the regions before, during and after the transition region (22), the equations being a function of the power level and the predetermined limits and boundaries.

Energy Technology Data Exchange (ETDEWEB)

A probabilistic method for assessing the profitability of reactive power compensation devices such as capacitors, static VAR compensators and generators, which improve network security, was described. Since network development is limited by environmental constraints, power networks are operated close to their limits. Because of this fact transmission network planning increasingly relies on techno-economic models to improve network security and profitability. The proposed method consists of analyzing large numbers of constrained power system states, extracted from power system simulation exercises. The paper describes details of the method and provides an example of a numerical application on a part of the French power transmission system. 10 refs., 8 figs.

Energy Technology Data Exchange (ETDEWEB)

We show that specially designed two-dimensional arrangements of full elastic cylinders embedded in a nonviscous fluid or gas define (in the homogenization limit) a new class of acoustic metamaterials characterized by a dynamical effective mass density that is anisotropic. Here, analytic expressions for the dynamical mass density and the effective sound velocity tensors are derived in the long wavelength limit. Both show an explicit dependence on the lattice filling fraction, the elastic properties of cylinders relative to the background, their positions in the unit cell, and their multiple scattering interactions. Several examples of these metamaterials are reported and discussed.

Energy Technology Data Exchange (ETDEWEB)

The theoretical alignment limit for focused ion beam (FIB) implantation was deduced from the calculated resolution for the detection of an alignment mark. The alignment resolution varies with the signal to noise ratio and there is an optimum current which gives the best resolution. The alignment resolution epsilon/sub sigma/ is approximately 0.006 ..mu..m for a 160 keV Si/sup ++/ beam from our FIB implanter. The measured alignment error is approximately 0.06 ..mu..m and the main reason of this discrepancy is vibration. The ultimate limit on the alignment error can be reached through improvements in the implanter system.

Science.gov (United States)

In the present work we introduce a novel multi-agent model with the aim to reproduce the dynamics of a double auction market at microscopic time scale through a faithful simulation of the matching mechanics in the limit order book. The agents follow a noise decision making process where their actions are related to a stochastic variable, the market sentiment, which we define as a mixture of public and private information. The model, despite making just few basic assumptions over the trading strategies of the agents, is able to reproduce several empirical features of the high-frequency dynamics of the market microstructure not only related to the price movements but also to the deposition of the orders in the book.

Energy Technology Data Exchange (ETDEWEB)

ASME Subcommittee 2 on materials presented a series of questions to PVRC regarding the acceptability of using the criteria of ASME Section 2, Part D, Appendix 1 for extending design limits for AISI 304 stainless steel beyond 1,500 F to 2,000 F and Alloy 800 HT from 1,650 F to 1,800 F respectively. This paper describes a project supported by PVRC to try and find an answer to this question. The project consisted of three parts. The first was a survey to determine the intent behind the wording of the ASME criteria in order to make an extrapolation of methods for setting design limits to higher temperatures. The second was a demonstration of a methodology for developing very high temperature limits, using a set of creep data for Alloy 800 HT. The third was a parametric study to evaluate the feasibility of using the minimum creep rate based deformation criterion used in the ASME Code to set strain related ...