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1

Physiological effects of manipulating the level of insulin-degrading enzyme in insulin-producing cells of Drosophila  

UK PubMed Central (United Kingdom)

Insulin-degrading enzyme (IDE) degrades insulin and other peptides, including the Aβ peptide of Alzheimer’s disease. However, the mechanism by which IDE acts on its substrates...Full Text Available

2011-01-01

2

Therapeutic Vaccination in Chronic Hepatitis B: Preclinical Studies in the Woodchuck  

UK PubMed Central (United Kingdom)

Recommended treatment of chronic hepatitis B with interferon-α and/or nucleos(t)ide analogues does not lead to a satisfactory result. Induction of HBV-specific T cells by therapeutic...Full Text Available

2010-01-01

3

Study on the separation characteristics of tritiated water vapor adsorption.  

Science.gov (United States)

In order to reduce the air concentration of (sup 3)H in the reactor buiIding of Wolsung Heavy Water Reactor, a computer code for estimation of adsorption behavior was programmed based on an equation derived for analysis of water vapor adsorption, and a ba...

1991-01-01

4

Kombinierte Flie?- und Grenzbedingungen  

British Library Electronic Table of Contents (United Kingdom)

Zusammenfassung Eine genauere Untersuchung der bekannten Modelle isotropen Materialverhaltens (z.B. von Mises, Tresca, Mohr-Coulomb, Drucker-Prager usw.) zeigt, dass sie selten mit Versuchsergebnissen ?bereinstimmen. Modelle mit inkompressiblen Eigenschaften sch?tzen oft das Materialverhalten bei mehraxialen Zugbelastungen falsch ein. Beim Flie?en unter Druck liefern die Modelle mit kompressiblen Eigenschaften unzul?ssige Werte der Querkontraktionszahl. Erfahrungen zeigen, dass es schwierig ist, mehrdimensionales Materialverhalten bei h?ufig fehlenden Informationen werkstoffgerecht abzubilden. Viele Modelle liefern akzeptable Ergebnisse nur f?r bestimmte Bereiche des Spannungsraumes. Diese Beobachtung hat auf die Idee gef?hrt, ,,bew?hrte?? Modelle miteinander zu verbinden. In diesem Artike...

2008-01-01

5

Detection of high-frequency radiation sources during the 2004 Parkfield earthquake by a matched filter analysis  

Science.gov (United States)

Introduction Uchide and Ide [SSA Spring Meeting, 2009] proposed a new framework for studying the scaling and overall nature of earthquake rupture growth in terms of cumulative moment functions. For better understanding of rupture growth processes, spatiotemporally local processes are also important. The nature of high-frequency (HF) radiation has been investigated for some time, but its role in the earthquake rupture process is still unclear. A wavelet analysis reveals that the HF radiation (e.g., 4 - 32 Hz) of the 2004 Parkfield earthquake is peaky, which implies that the sources of the HF radiation are isolated in space and time. We experiment with applying a matched filter analysis using small template events occurring near the target event rupture area to test whether it can reveal the HF radiation sources for a regular large earthquake. Method We design a matched filter for multiple components and stations. Shelly et al. [2007] attempted identifying ...

2009-12-01