WorldWideScience

Sample records for medicinal plants anise

  1. Role of Some Medicinal Herbs Plants (Anise and Chamomile) in Male Rats Intoxicated with Metacide Pesticide

    International Nuclear Information System (INIS)

    This present study was undertaken to evaluate the effect of some medicinal herbs plants such as anise and chamomile (300 mg/kg b.wl) for five weeks on some biochemical changes induced in rats administrated daily oral dose of organophosphorus pesticide metacide at level of 1.4 mg/kg b.wt for live weeks. The data showed that the metacide pesticides caused disturbance in liver and kidney function revealed as significant increased in serum total lipids, triglycerides, total free amino, biliburine, total cholesterol, creatinine, urea and uric acid. Moreover, a significant decreased in total proteins. Also thyroxine hormone (T4) was increased while triiodothyronine (T 3) was decreased. The results also revealed that both anise and chamomile exhibited an improvement and highly affective in attenuation of metacide pesticide caused oxidative damage, disturbance and injury induced in liver, kidney and thyroid hormone function

  2. EFFECT OF USING SOME MEDICINAL PLANTS (ANISE, CHAMOMILE AND GINGER) ON PRODUCTIVE AND PHYSIOLOGICAL PERFORMANCE OF JAPANESE QUAIL

    International Nuclear Information System (INIS)

    This experiment was conducted to evaluate the effects of adding medicinal plants to Japanese quail diet on their performance and some metabolic functions. Four hundred, one day old, unsexed Japanese quails were used in this study. Quails were divided equally into four groups of 100 birds each according to medicinal plant additives. Group one was control (without additives, and the other groups contained 0.3% from anise (group 2), chamomile (group 3) and ginger (group 4). The end of the experiment was terminated when birds were 6 weeks old. Body weight, feed intake, some organs weight and some blood parameters were measured.The results indicated that addition of medicinal plants (anise, chamomile and ginger) improved growth rate, carcass and the relative weights of spleen, ovary and testis. Also, significant increases were observed in RBC, WBC, Hb, PCV, total protein and globulin. There was reduction in cholesterol in treated groups as compared to the control.The present results confirmed the beneficial effects of dietary medicinal plants (anise, chamomile and ginger) to improve the health condition as well as the productive and physiological characteristics of quails

  3. Identification of Puccinia pimpinellae on Anise Plant in Egypt and Its Control

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    Wesam I.A. Saber

    2009-01-01

    Full Text Available An emerging problem for the wider adoption of anise plantation in Egypt is the damage caused by the rust fungus. The detailed description and taxonomic studies (using light and scanning electron microscopy show that such an obligate parasite fungus (Puccinia pimpinellae is autoecious microcyclic (uredinial-telial stage only. Among tested Apiaceae plants, the host range test proved the specificity of the rust fungus to anise. To the researcher’s knowledge, this is the first investigated record of a rust fungus on Pimpinella anisum plants in Egypt. The effectiveness of some plant resistance elicitors and two active chitinase producers; Bacillus subtilis Bio4 and isolated Trichoderma harizianum CH4 (both of them recorded the highest clear zone/colony size ratio on chitin agar plates in controlling anise rust disease and on growth and yield of anise were evaluated in two successive growing seasons. Spraying chitosan at 1000 ppm was the most potent in reducing Disease Severity (DS and Incidence (DI as well as improving plant height, chlorophyll content, inflorescence No. plant-1 (74.2 and 76, 1000-fruit weight (2.94 and 2.83 g and anise yield (646.8 and 670.0 kg fed-1, during both seasons. B. subtilis Bio4 and T. harizianum CH4 showed moderate effect on the tested parameters.

  4. Medicinal Plants.

    Science.gov (United States)

    Phillipson, J. David

    1997-01-01

    Highlights the demand for medicinal plants as pharmaceuticals and the demand for health care treatments worldwide and the issues that arise from this. Discusses new drugs from plants, anticancer drugs, antiviral drugs, antimalarial drugs, herbal remedies, quality, safety, efficacy, and conservation of plants. Contains 30 references. (JRH)

  5. The influence of fertilization on yield of caraway, anise and coriander in organic agriculture

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    Aćimović Milica G.

    2013-01-01

    Full Text Available Many plants of Apiaceae family have long been well known because of flavorful aromatic spice and, because of its healing properties, are often used in folk medicine and in cooking. In our study three plants of this family were included: caraway (Carum carvi L., anise (Pimpinella anisum L. and coriander (Coriandrum sativum L.. Regarding good agro-ecological conditions for growing these plants in Serbia, and a new world trend of increasing organic agricultural production, the aim of this study was to investigate the effects of application of various types of fertilizers on yield of studied plant species. The field experiment was carried out during the years of 2011 and 2012, in three localities in Vojvodina Province with the local ecotypes and six different treatments (control, ‘Slavol’, ‘Bactofil B-10’, ‘Royal Ofert’, vermicompost and NPK. The highest caraway yield was obtained by the application of biofertilizer ‘Bactofil B-10’. As regards anise and coriander the highest yield was achieved by the application of chemical fertilizer. The most effective organic fertilizers were the following: vermicompost for anise and specific poultry manure ‘Royal Ofert’ granules for coriander.

  6. Medicinal plants: conception / contraception.

    Science.gov (United States)

    Chaing, H S; Merino-chavez, G; Yang, L L; Wang, F N; Hafez, E S

    1994-01-01

    Researchers have conducted considerable experiments on the effectiveness and therapeutic values of Chinese herbs and parts of plants. We should not ignore the significance of natural medicine. The Chinese have been perfecting medicinal therapy based on the raw ingredients of plants/herbs and their derivatives for thousands of years. Chinese practitioners of traditional medicine prescribe medicines based on yin and yang. Traditional medicine is communicated in a verb or written form. Natural resources used in traditional medicine to treat diseases are not limited to just medicinal plants but also include animals, shell fish, and minerals. Parts of plants used in traditional medicine are leaves, stems, flowers, bark, and root. Chinese medicine is the world's oldest continuous surviving tradition. The Chinese experimented with local plants, often resulting in mild to violent reactions. This process allowed them to become familiar with poisonous plants and those that could relieve pain or successfully treat illness. Current allopathic medicines are composed of synthetic compounds copied from natural chemical derivatives, which tend to be more potent than the original compound. Some medicinal plants used to effect conception/contraception include Striga astiatica (contraceptive); Eurycoma longifolia (male virility); and a mixture of lengkuas, mengkudu masak, black pepper seeds, ginger, salt, and 2 eggs (increase libido). Women in Malaysia take jamu to preserve their body shape and to provide nutrition during pregnancy. Praneem causes local cell-mediated immunity in the uterus. Clinical trials of Praneem with or without the hCG vaccine are planned. PMID:12287843

  7. Plants and Medicinal Chemistry

    Science.gov (United States)

    Bailey, D.

    1977-01-01

    This is the first of two articles showing how plants that have been used in folk medicine for many centuries are guiding scientists in the design and preparation of new and potent drugs. Opium and its chemical derivatives are examined at length in this article. (Author/MA)

  8. Phytochemistry of Medicinal Plants

    OpenAIRE

    Dharmendra Singh; Jyoti Saxena; Mamta Saxena; Rajeev Nema

    2013-01-01

    Medicinal plants are a rich source of bioactive phytochemicals or bionutrients. Studies carried out during the past 2–3 decades have shown that these phytochemicals have an important role in preventing chronic diseases like cancer, diabetes and coronary heart disease. The major classes of phytochemicals with disease-preventing functions are dietary fibre, antioxidants, anticancer, detoxifying agents, immunity-potentiating agents and neuropharmacological agents. Each class of these functional ...

  9. MEDICINAL PLANTS AGAINST LIVER DISEASES

    OpenAIRE

    Pandey Govind

    2011-01-01

    India is the largest producer of medicinal plants and is rightly called the “Botanical Garden of the World”. The medicinal plants have very important place in the health and vitality of human beings as well as animals. As per the WHO estimates, about three quarters of the world’s population currently use herbs and other traditional medicines to cure various diseases, including liver disorders. Hence, several phytomedicines (medicinal plants or herbal drugs) are now used for the prevention and...

  10. MEDICINAL PLANTS AGAINST LIVER DISEASES

    Directory of Open Access Journals (Sweden)

    Pandey Govind

    2011-05-01

    Full Text Available India is the largest producer of medicinal plants and is rightly called the “Botanical Garden of the World”. The medicinal plants have very important place in the health and vitality of human beings as well as animals. As per the WHO estimates, about three quarters of the world’s population currently use herbs and other traditional medicines to cure various diseases, including liver disorders. Hence, several phytomedicines (medicinal plants or herbal drugs are now used for the prevention and treatment of various liver disorders. Although experimental studies have been conducted on a number of these plants and their formulations, however, only some plants have clearly shown the hepatogenic / hepatoprotective effects against liver diseases or hepatotoxicity caused by variety of hepatotoxic agents such as chemicals, drugs, pollutants, and infections from parasites, bacteria or viruses (e.g., hepatitis A, B and C, etc. Indeed, to obtain satisfactory herbal drugs for treating severe liver diseases, the medicinal plants must be evaluated systematically for properties like antiviral activity (Hepatitis B, Hepatitis C, etc., antihepatotoxicity activity (antioxidants and others, stimulation of liver regeneration and choleretic activity. A combination of different herbal extracts / fractions is likely to provide desired activities to cure severe liver diseases. The medicinal plants contain several phytochemicals which possess strong antioxidant property, leading to antihepatotoxic activity.

  11. Plants and Medicinal Chemistry--2

    Science.gov (United States)

    Bailey, D.

    1977-01-01

    Second of a two part article on the influence of plants on medicinal chemistry. This part considers how drugs work, the attempts to develop anaesthetics safer than cocaine, and useful poisons. (Author/SL)

  12. A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice

    Scientific Electronic Library Online (English)

    Alfonso, Díaz; Izel, Vargas-Perez; Lidia, Aguilar-Cruz; Roberto, Calva-Rodríguez; Samuel, Treviño; Berenice, Venegas; Irma Rosalía, Contreras-Mora.

    2014-08-01

    Full Text Available Diarrhea is a serious public health problem in Mexico and other countries. A widely used alternative in the treatment of diarrhea is the use of herbal medicines. Infusions of chamomile and star anise possess anti-inflammatory and antimotility properties that could help alleviate gastrointestinal dis [...] orders. The aim of this study was to determine the effect of the mixture of chamomile and star anise infusions on gastrointestinal activity in mice. A gastrointestinal assessment of the mixture of chamomile and star anise was carried out in mice, and the percentage of advance of administered activated carbon through the intestinal tract of the animals was measured. Furthermore, the diarrhea model was induced with castor oil. The infusions were prepared using a mix with a 50:50 ratio of the herbs, and were administered at Mix-10, 20, 40 and 80 (mg/kg) orally. The results indicate that Mix-40 and Mix-80 decreased the completion percentage of the activated carbon, delayed the appearance of diarrhea and decreased the number of evacuations in comparison with the control group. This suggests that the combination of chamomile and star anise can be used as an alternative antidiarrheal treatment.

  13. Medicinal plants and antimicrobial activity.

    Science.gov (United States)

    Ríos, J L; Recio, M C

    2005-08-22

    In the present paper, we analyze the past, present and future of medicinal plants, both as potential antimicrobial crude drugs as well as a source for natural compounds that act as new anti-infection agents. In the past few decades, the search for new anti-infection agents has occupied many research groups in the field of ethnopharmacology. When we reviewed the number of articles published on the antimicrobial activity of medicinal plants in PubMed during the period between 1966 and 1994, we found 115; however, in the following decade between 1995 and 2004, this number more than doubled to 307. In the studies themselves one finds a wide range of criteria. Many focus on determining the antimicrobial activity of plant extracts found in folk medicine, essential oils or isolated compounds such as alkaloids, flavonoids, sesquiterpene lactones, diterpenes, triterpenes or naphtoquinones, among others. Some of these compounds were isolated or obtained by bio-guided isolation after previously detecting antimicrobial activity on the part of the plant. A second block of studies focuses on the natural flora of a specific region or country; the third relevant group of papers is made up of specific studies of the activity of a plant or principle against a concrete pathological microorganism. Some general considerations must be established for the study of the antimicrobial activity of plant extracts, essential oils and the compounds isolated from them. Of utmost relevance is the definition of common parameters, such as plant material, techniques employed, growth medium and microorganisms tested. PMID:15964727

  14. Phytochemical constituents of some Indian medicinal plants

    OpenAIRE

    Dhandapani, R.; Sabna, B.

    2008-01-01

    Alkaloids, tannins, saponins, steroid, terpenoid, flavonoids, phlobatannin and cardie glycoside distribution in seven medicinal plants belonging to different families were assessed and compared. The medicinal plants investigated were Aegle marmelos, Cynodon dactylon, Eclipta prostrata, Moringa pterygosperma, Pongamia pinnata, Sida acuta and Tridax procumbens. The significance of the plants in traditional medicine and the importance of the distribution of these chemical constituents were discu...

  15. Antioxidant Potential of Different Medicinal Plants

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    Vasanthi P

    2015-11-01

    Full Text Available Medicinal plants are the resource of new drug. Most of the modern medicines are produced indirectly from medicinal plants. Plants are directly used as medicines by a majority of cultures around the world. Studying medicinal plants helps to understand plant toxicity and protect human and animals from natural poisons. Medicinal plants are the important sources for pharmaceutical manufacturing. In developing countries, herbal medicines are considered to be readily available, accessible, affordable, culturally acceptable and sustainable than Western medicines. In developed countries, the popularity of herbal medicines is continuing to grow, particularly for the treatment of certain disease. Medicinal plants have always been considered as a source of healthy life for people. Therapeutical properties of medical plants are very useful in healing various diseases and the advantage of these medicinal plants is natural. Researchers are increasingly turning their attention to natural products and looking for new, lead to develop better drugs. In the present study, the four different medicinal plants Zingiber officinalis, Terminalia arjuna, Punica granatum, Rauvolfia serpentine exerted antioxidative effects. The results suggest that aqueous extract of Terminalia arjuna possesses the potent antioxidant property when compared to other plant extracts. In turn, it has therapeutic potential for the prevention of coronary artery and renal diseases.

  16. Radioactive properties of medicinal plants

    International Nuclear Information System (INIS)

    Full text: A complicated cycle of various compounds' synthesis is provided by plants in the process of their development. The synthesized compounds are necessary to maintain the life of all living organisms both in water and on the land. Together with the organic compounds all known natural radionuclides are accumulated by the plants. Many plants possess the ability to accumulate some elements, whose concentration in the plants may be much higher than that in the soils and water sources. It is well known that the plants are basic or initial raw materials for producing numerous food products, as well as medicinal preparations. The radionuclides, accumulated in the plants, may pass to the human organism through the products and drugs, and may become a source of internal radiation. Accumulation of the radionuclides in various human organs above the maximal acceptable concentration (MAC) may lead to various pathologic changes. That is why it is a necessary and urgent problem to carry out investigations of the radioactive properties of the plants (i.e. to determine their radioecological cleanliness) before using the medicinal plant for pharmacological purposes. In the present work we investigated the radioactive processes of kinds of medicinal plants by the method of semi-conductor gamma-spectrometry. Measurements of the gamma-spectra of the plants' leach were carried out with the help of a gamma-spectrometer with a Ge(Li) detector accompanied by a 4096-channel analyzer. Responsive volume of the detector was 40 cm3, energy resolution with respect to 1333 keV 60Co line was 3 keV. In the measured spectra we observed clearly photo-peaks belonging to uranium-238 family: 186 keV 226Ra; 295, 351 keV 214Pb; 609, 1120, 1764 keV 214Bi; and those belonging to thorium - 232 family: 339, 911, 968 keV 228Ac; 583, 2614 keV 208Te; as well as the photo-peak of the natural radionuclide 40K with the energy 1460 keV. From the proper gamma-lines, observed in the spectra, we calculated the concentration of the radionuclides. While choosing the analytical lines we took into account the degree of disturbance of the radioactive equilibrium between the maternal and filial radionuclides. The determined magnitudes for the natural radionuclides in the leaches of the investigated plants are presented. It is shown that the radioactivity of investigated plants is conditioned by decay of the natural radionuclides 238U, 226Ra, 232Th, and 40K. Maximal accumulation is observed for 40K and 232Th.Thorium minerals are dissolved in natural waters much weaker than those of uranium. However, the concentration of thorium in the investigated samples is (1.8-4.0) tunes higher than the concentration of uranium. This fact reveals that the plants absorb the isotopes of thorium in amounts, which are proportional to their concentration in soils. In the plants growing in the similar soil-climate conditions the concentration uranium is different. This fact testifies that the accumulation of uranium by the plants may depend on the specific features. Concentration of radium in the plants is comparable with its concentration in the soils that may be explained by ability of plants to accumulate radium in amounts, which exceed its concentration in a culture medium. In different kinds of the plants' leach we observe various concentrations of potassium - (24-7-51)·10-6 g/g - that reveals different needs of the plants with respect to potassium. The observed concentrations of the natural radionuclides are in the MAC limits. That testifies a relative radioecological well-being of the investigated plants

  17. The Effect of Drought Stress on the Essential Oil Content and Some of the Biochemical Characteristics of Anise Hyssop (Agastache foeniculum [Pursh] Kuntze

    Directory of Open Access Journals (Sweden)

    Sajedeh Saeedfar

    2015-06-01

    Full Text Available Plot trials were carried out in a research field in Tehran (Iran to determine the effect of drought stress on the essential oil content and some of the plant biochemical characteristics of Anise Hyssop (Agastache foeniculum [Pursh] Kuntze, which is a valuable medicinal plant. Drought stress was conducted at different levels including: well-water (100% FC, mild drought stress (85% FC, moderate drought stress (70% FC, severe drought stress (55% FC, 100% FC (vegetative stage 85% FC (reproductive stage, 100% FC (vegetative stage 70% FC (reproductive stage, and 85% FC (vegetative stage 100% FC (reproductive stage. The experiment was arranged as a RCBD with three replications. The output results showed that, water deficit stress significantly (P?0.05 increased activities of antioxidant enzymes (Superoxide Dismutase, Catalase, Glutathione Peroxidase as well as Essential Oil yield and Abscisic Acid content. Lipid and protein oxidation (malondialdehyde and dityrosine contents also increased significantly under severe water deficit stress. According to the results, severe drought conduction (55% FC is the optimum level of soil moisture to plant Anise Hyssop under water deficit stress.

  18. Use of Medicinal Plants of District Bannu in Unani Medicines

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    Shahzeb

    2013-06-01

    Full Text Available The present research work was carried out during 2012 in district Bannu to study the use of medicinal plants in Unani medicine. A total of 35 Unani medicines were reported and arranged systematically along with name of product, available form, company name, name of the plants/parts used in the drugs, family name and purpose of uses. During the research it was found that most of the members of Lamiaceae, Asteraceae and Rhamnaceae are used in these medicines. Plants which were used commonly in these medicines in one form or the other are Ziziphus jujuba, Foeniculum vulgare, Solanum nigrum, Ocimum cannum and Zingber officinale. It was noted that these products are mostly available in syrup form, rarely in tablets form (Hab –khoom Safa, Mensorine, Scony Tablets and one only one product in dry powder (Supari Pak. It is generally believed that these medicines have no side effect. Interestingly one medicine is suggested for many diseases as per the given instructions in the medicine pack. It was also noted that the manufacturers of these medicines are mostly not registered that’s why incomplete addresses along with the wrongly spellings plant name given on the medicine packs. The main purpose of the research was to identify and enlist the plants systematically used in these medicines.

  19. Use of Medicinal Plants of District Bannu in Unani Medicines

    OpenAIRE

    Shahzeb; Sultan Mehmood; Rehman ullah khan; Saad Ullah Khan

    2013-01-01

    The present research work was carried out during 2012 in district Bannu to study the use of medicinal plants in Unani medicine. A total of 35 Unani medicines were reported and arranged systematically along with name of product, available form, company name, name of the plants/parts used in the drugs, family name and purpose of uses. During the research it was found that most of the members of Lamiaceae, Asteraceae and Rhamnaceae are used in these medicines. Plants which were used commonly in ...

  20. Electrophysiological investigation of the cellular effect of anethole, the chief constitute of anise, on F1 neuronal excitability in garden snail

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    Zahra Ghasemi

    2011-04-01

    Full Text Available Introduction: Anethole is the main constituent of Pimpinella anisum L. (anise, a herbaceous annual plant which has several therapeutic effects. In the folk medicine, anise is employed as an antiepileptic drug. Specifically, this study was focused on the cellular effect of anethole, an aromatic compound in essential oils from anise and camphor. Anethole has various physiological effects on the cardiovascular system and smooth and skeletal muscles. However, despite these persistent effects, there is little information available about the actions of anethole on nerve cells. Therefore, a major goal of the present research was to investigate the possible cellular mechanisms underlying the effect of anethole on the neural excitability and action potential characteristics in snail neurons. Methods: Intracellular recordings were made under the current clamp condition on F1 cells of Helix aspersa. Following extracellular application of anethole (0.5% or 2%, changes in the firing pattern and action potential parameters were assessed and compared to control condition. Results: Application of anethole (0.5% and 2% led to a significant increase in the action potential amplitude and a reduction in the peak area and time to peak. In the presence of 0.5% anethole, the after hyperpolarization (AHP amplitude was significantly decreased, while the firing frequency of neurons was increased. However, 2% anethole did not affect the AHP amplitude, but significantly reduced the firing frequency of action potentials. Conclusion: Based on the effect of anethole on the action potential parameters, it can be concluded that it probably affects the voltage gated ion channels function, including Ca2+ channels and/or Ca2+ dependent K+ channels activity.

  1. Medicinal plant markets and trade in Maputo, Mozambique

    DEFF Research Database (Denmark)

    Krog, Mogens Pedersen; Falcâo, Mario P.; Olsen, Carsten Smith

    Medicinal plants and traditional medicine are important to urban and rural livelihoods in Mozambique. This study presents a preliminary investigation of the structure and conduct of medicinal plant markets in Maputo.......Medicinal plants and traditional medicine are important to urban and rural livelihoods in Mozambique. This study presents a preliminary investigation of the structure and conduct of medicinal plant markets in Maputo....

  2. From Curanderas to Gas Chromatography: Medicinal Plants

    Science.gov (United States)

    O'Connell, Mary; Lara, Antonio

    2005-01-01

    The Medicinal Plants of the Southwest summer workshop is an inquiry-based learning approach to increase interest and skills in biomedical research. Working in teams, Hispanic and Native American students discover the chemical and biological basis for the medicinal activity of regional plants used by healers. (Contains 4 tables and 1 figure.)

  3. Determination of trace elements in Syrian medicinal plants and their infusions by energy dispersive X-ray fluorescence and total reflection X-ray fluorescence spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Khuder, A. [Department of Chemistry, Atomic Energy Commission, P.O. Box 6091, Damascus (Syrian Arab Republic)], E-mail: scientific2@aec.org.sy; Sawan, M.Kh.; Karjou, J. [Department of Chemistry, Atomic Energy Commission, P.O. Box 6091, Damascus (Syrian Arab Republic); Razouk, A.K. [Department of Agriculture, Atomic Energy Commission, P.O. Box 6091, Damascus (Syrian Arab Republic)

    2009-07-15

    X-ray fluorescence (XRF) and total-reflection X-ray fluorescence (TXRF) techniques suited well for a multi-element determination of K, Ca, Mn, Fe, Cu, Zn, Rb, and Sr in some Syrian medicinal plant species. The accuracy and the precision of both techniques were verified by analyzing the Standard Reference Materials (SRM) peach-1547 and apple leaves-1515. A good agreement between the measured concentrations of the previously mentioned elements and the certified values were obtained with errors less than 10.7% for TXRF and 15.8% for XRF. The determination of Br was acceptable only by XRF with an error less than 24%. Furthermore, the XRF method showed a very good applicability for the determination of K, Ca, Mn, Fe, Cu, Zn, Rb, Sr, and Br in infusions of different Syrian medicinal plant species, namely anise (Anisum vulgare), licorice root (Glycyrrhiza glabra), and white wormwood (Artemisia herba-alba)

  4. Determination of trace elements in Syrian medicinal plants and their infusions by energy dispersive X-ray fluorescence and total reflection X-ray fluorescence spectrometry

    International Nuclear Information System (INIS)

    X-ray fluorescence (XRF) and total-reflection X-ray fluorescence (TXRF) techniques suited well for a multi-element determination of K, Ca, Mn, Fe, Cu, Zn, Rb, and Sr in some Syrian medicinal plant species. The accuracy and the precision of both techniques were verified by analyzing the Standard Reference Materials (SRM) peach-1547 and apple leaves-1515. A good agreement between the measured concentrations of the previously mentioned elements and the certified values were obtained with errors less than 10.7% for TXRF and 15.8% for XRF. The determination of Br was acceptable only by XRF with an error less than 24%. Furthermore, the XRF method showed a very good applicability for the determination of K, Ca, Mn, Fe, Cu, Zn, Rb, Sr, and Br in infusions of different Syrian medicinal plant species, namely anise (Anisum vulgare), licorice root (Glycyrrhiza glabra), and white wormwood (Artemisia herba-alba). (author)

  5. Determination of trace elements in Syrian medicinal plants and their infusions by energy dispersive X-ray fluorescence and total reflection X-ray fluorescence spectrometry

    Science.gov (United States)

    Khuder, A.; Sawan, M. Kh.; Karjou, J.; Razouk, A. K.

    2009-07-01

    X-ray fluorescence (XRF) and total-reflection X-ray fluorescence (TXRF) techniques suited well for a multi-element determination of K, Ca, Mn, Fe, Cu, Zn, Rb, and Sr in some Syrian medicinal plant species. The accuracy and the precision of both techniques were verified by analyzing the Standard Reference Materials (SRM) peach-1547 and apple leaves-1515. A good agreement between the measured concentrations of the previously mentioned elements and the certified values were obtained with errors less than 10.7% for TXRF and 15.8% for XRF. The determination of Br was acceptable only by XRF with an error less than 24%. Furthermore, the XRF method showed a very good applicability for the determination of K, Ca, Mn, Fe, Cu, Zn, Rb, Sr, and Br in infusions of different Syrian medicinal plant species, namely anise ( Anisum vulgare), licorice root ( Glycyrrhiza glabra), and white wormwood ( Artemisia herba-alba).

  6. Effect of NP and foliar spray on growth and chemical compositions of some medicinal Apiaceae plants grow in arid regions in Egypt

    Directory of Open Access Journals (Sweden)

    Khalid A Khalid

    2012-01-01

    Full Text Available Arid regions in Egypt are characterized by poor nutrients such as macro and microelements and unfavorable environmental conditions which negatively affect growth and productivity of medicinal and aromatic plants including anise (Pimpinella anisum L., coriander (Coriandrum sativum L. and sweet fennel (Foeniculum vulgare var. Dolce plants. Thus, the main objective of the present investigation was to study the effect of different levels of NP fertilizers, trace elements and their interactions on the morphological and biochemical contents of these three plants under arid regions conditions. The effects of NP and trace elements on the growth (height, leaf number, branch number, umbel number, fresh weight, dry weight and fruit yield per plant was measured and quantitative analysis of essential oils, fixed oil, total carbohydrates, soluble sugars and nutrient content of anise, coriander and sweet fennel were performed. The most effective rate was N3P3 x trace elements interaction, resulting in a positive increase in vegetative growth characters. The highest values of vegetative growth characters were 53.4, 45.9, 10.3, 33.5, 36.8, 11.8 and 7.9, respectively for anise; 83.0, 69.3, 9.8, 29.0, 34.0, 17.5 and 14.4, respectively for coriander; 89.8, 32.6, 7.8, 22.9, 257.8, 99.1 and 27.8, respectively for sweet fennel. As well as N3P3 x trace elements led to higher biochemical contents than the control. The increases were 0.9, 0.3 and 0.9% in essential oil; 5.4, 4.4 and 3.7% in fixed oil, 9, 7.9 and 8.2% in total carbohydrates; 2.4, 2.8 and 1.6% in soluble sugars; 5.0, 7.5 and 14.4% in crude protein; 0.8, 2.0 and 2.3% in nitrogen; 1.5, 0.6 and 0.4% in phosphorous; 1.3, 1.2 and 1.7% in potassium for anise, coriander and sweet fennel, respectively.

  7. Effect of NP and foliar spray on growth and chemical compositions of some medicinal Apiaceae plants grow in arid regions in Egypt

    Scientific Electronic Library Online (English)

    Khalid A, Khalid.

    2012-09-01

    Full Text Available Arid regions in Egypt are characterized by poor nutrients such as macro and microelements and unfavorable environmental conditions which negatively affect growth and productivity of medicinal and aromatic plants including anise (Pimpinella anisum L.), coriander (Coriandrum sativum L.) and sweet fenn [...] el (Foeniculum vulgare var. Dolce) plants. Thus, the main objective of the present investigation was to study the effect of different levels of NP fertilizers, trace elements and their interactions on the morphological and biochemical contents of these three plants under arid regions conditions. The effects of NP and trace elements on the growth (height, leaf number, branch number, umbel number, fresh weight, dry weight and fruit yield per plant) was measured and quantitative analysis of essential oils, fixed oil, total carbohydrates, soluble sugars and nutrient content of anise, coriander and sweet fennel were performed. The most effective rate was N3P3 x trace elements interaction, resulting in a positive increase in vegetative growth characters. The highest values of vegetative growth characters were 53.4, 45.9, 10.3, 33.5, 36.8, 11.8 and 7.9, respectively for anise; 83.0, 69.3, 9.8, 29.0, 34.0, 17.5 and 14.4, respectively for coriander; 89.8, 32.6, 7.8, 22.9, 257.8, 99.1 and 27.8, respectively for sweet fennel. As well as N3P3 x trace elements led to higher biochemical contents than the control. The increases were 0.9, 0.3 and 0.9% in essential oil; 5.4, 4.4 and 3.7% in fixed oil, 9, 7.9 and 8.2% in total carbohydrates; 2.4, 2.8 and 1.6% in soluble sugars; 5.0, 7.5 and 14.4% in crude protein; 0.8, 2.0 and 2.3% in nitrogen; 1.5, 0.6 and 0.4% in phosphorous; 1.3, 1.2 and 1.7% in potassium for anise, coriander and sweet fennel, respectively.

  8. Effect of NP and foliar spray on growth and chemical compositions of some medicinal Apiaceae plants grow in arid regions in Egypt

    Directory of Open Access Journals (Sweden)

    Khalid A Khalid

    2012-09-01

    Full Text Available Arid regions in Egypt are characterized by poor nutrients such as macro and microelements and unfavorable environmental conditions which negatively affect growth and productivity of medicinal and aromatic plants including anise (Pimpinella anisum L., coriander (Coriandrum sativum L. and sweet fennel (Foeniculum vulgare var. Dolce plants. Thus, the main objective of the present investigation was to study the effect of different levels of NP fertilizers, trace elements and their interactions on the morphological and biochemical contents of these three plants under arid regions conditions. The effects of NP and trace elements on the growth (height, leaf number, branch number, umbel number, fresh weight, dry weight and fruit yield per plant was measured and quantitative analysis of essential oils, fixed oil, total carbohydrates, soluble sugars and nutrient content of anise, coriander and sweet fennel were performed. The most effective rate was N3P3 x trace elements interaction, resulting in a positive increase in vegetative growth characters. The highest values of vegetative growth characters were 53.4, 45.9, 10.3, 33.5, 36.8, 11.8 and 7.9, respectively for anise; 83.0, 69.3, 9.8, 29.0, 34.0, 17.5 and 14.4, respectively for coriander; 89.8, 32.6, 7.8, 22.9, 257.8, 99.1 and 27.8, respectively for sweet fennel. As well as N3P3 x trace elements led to higher biochemical contents than the control. The increases were 0.9, 0.3 and 0.9% in essential oil; 5.4, 4.4 and 3.7% in fixed oil, 9, 7.9 and 8.2% in total carbohydrates; 2.4, 2.8 and 1.6% in soluble sugars; 5.0, 7.5 and 14.4% in crude protein; 0.8, 2.0 and 2.3% in nitrogen; 1.5, 0.6 and 0.4% in phosphorous; 1.3, 1.2 and 1.7% in potassium for anise, coriander and sweet fennel, respectively.

  9. [Plant hydroponics and its application prospect in medicinal plants study].

    Science.gov (United States)

    Zeng, Yan; Guo, Lan-Ping; Huang, Lu-Qi; Sun, Yu-Zhang

    2007-03-01

    This article introduced the theorem and method of hydroponics. Some examples of studies in agriculture and forestry were presented, the effects of elements, environmental stress and hormones on physiology of medicinal plants by using hydroponics were analyzed. It also introduced the feasibility and advantage of hydroponics in intermediate propagation and allelopathy of medicinal plant. And finally it made the conclusion that the way of hydroponics would be widely used in medicinal plant study. PMID:17511136

  10. Medicinal plants: production and biochemical characterization

    International Nuclear Information System (INIS)

    Recent advances in the area of biotechnology offer some possibility for the development of new technologies for the conservation, characterization and mass production of medicinal plant species, (i.e. in vitro cell culture techniques for the mass production of sterile, consistent, standardized medicinal plant materials). This paper discussed the following subjects - plant tissue culture, de novo shoot organogenesis, de novo root organogenesis, somatic embryogenesis, large scale propagation in bioreactors and discovery of unique biomolecules

  11. International congress on aromatic and medicinal plants

    International Nuclear Information System (INIS)

    Full Text : In Morocco, medicinal and aromatic plants occupy an important place in the traditional care system of a large number of local people. They are also economically strong potential, but unfortunately they are not valued enough. Indeed, Morocco by its privileged geographical position in the Mediterranean basin and its floristic diversity (with a total of over 4,200 species and subspecies of which over 500 are recognized as medicinal and aromatic plants), is a leading provider of traditional global market. In this context and given the back label of the natural global, group research and studies on Aromatic and Medicinal Plants (GREPAM), the Faculty of Semlalia and University Cadi Ayyad, organize: the International Congress on Medicinal and Aromatic Plants CIPAM 2009. The organization of this conference is part of scientific research developed by the GREPAM.

  12. Medicinal plants used in Kirklareli Province (Turkey).

    Science.gov (United States)

    Kültür, Sükran

    2007-05-01

    In this paper, 126 traditional medicinal plants from Kirklareli Province in Turkey have been reported. One hundred and twenty six plant species belonging to 54 families and among them 100 species were wild and 26 species were cultivated plants. Most used families were Rosaceae, Labiatae, Compositae and the most used plants were Cotinus coggyria, Sambucus ebulus, Achillea millefolium subsp. pannonica, Hypericum perforatum, Matricaria chamomilla var. recutita, Melissa officinalis subsp. officinalis, Juglans regia, Thymus longicaulis subsp. longicaulis var. subisophyllus, Malva sylvestris, Urtica dioica, Plantago lanceolata, Rosa canina, Ecballium elaterium, Artemisia absinthium, Viscum album subsp. album, Papaver rhoeas, Helleborus orientalis, Cydonia oblonga, Prunus spinosa subsp. dasyphylla, Rubus discolor, Sorbus domestica. A total of 143 medicinal uses were obtained. The traditional medicinal plants have been mostly used for the treatment of wounds (25.3%), cold and influenza (24.6%), stomach (20%), cough (19%), kidney ailments (18.2%), diabetes (13.4%). PMID:17257791

  13. ANTIMYCOTIC ACTIVITY OF SIX MEDICINAL PLANTS

    OpenAIRE

    VISHAL NARAYAN SHINDE

    2013-01-01

    The variable extracts of six medicinal plants prepared in 80% methanol and distilled water and were tested for their antimycotic activity against five different phytopathogenic fungi such as Alternaria carthami, Alternaria humicola, Fusarium oxysporum, Fusarium roseum, Pullularia pullulans. Among all the plant extracts, methanol extract of Lawsonia inermis and Hyptis sauvolens leaves were showed significant antifungal activity against targeted phytopathogens. Methanol extracts displayed maxim...

  14. Biological screening of Brazilian medicinal plants

    OpenAIRE

    Tânia Maria de Almeida Alves; Andréia Fonseca Silva; Mitzi Brandão; Telma Sueli Mesquita Grandi; Elza de Fátima A Smânia; Artur Smânia Júnior; Carlos Leomar Zani

    2000-01-01

    In this study, we screened sixty medicinal plant species from the Brazilian savanna ("cerrado") that could contain useful compounds for the control of tropical diseases. The plant selection was based on existing ethnobotanic information and interviews with local healers. Plant extracts were screened for: (a) molluscicidal activity against Biomphalaria glabrata, (b) toxicity to brine shrimp (Artemia salina L.), (c) antifungal activity in the bioautographic assay with Cladosporium sphaerospermu...

  15. ANTIVIRAL POTENTIAL OF MEDICINAL PLANTS: AN OVERVIEW

    Directory of Open Access Journals (Sweden)

    Ruwali Pushpa

    2013-06-01

    Full Text Available The term ‘Antiviral agents’ has been defined in very broad terms as substances other than a virus or virus containing vaccine or specific antibody which can produce either a protective or therapeutic effect to the clear detectable advantage of the virus infected host. The herbal medicine has a long traditional use and the major advantage over other medicines is their wide therapeutic window with rare side effects. There are some disadvantages of synthetic drugs like narrow therapeutic window and more importantly the various adverse side effects which occur quite frequently. Due to these disadvantages and other limitations, there is an increasing trend in the field of research for discovering new and noble drugs based on various herbal formulations. This review attempts to address the importance of developing therapeutic herbal formulations from various medicinal plants using the knowledge based on traditional system of medicines, the Ayurveda. Although natural products have been used by civilization since ancient times, only in recent decades has there been growing research into alternative therapies and the therapeutics use of natural products, especially those derived from plants. Plants synthesize and preserve a variety of biochemical products, many of which are extractable and used for various scientific investigations. Therefore, medicinal plants proved to be a major resort for the treatment of diseases and sicknesses by traditional healers in many societies.

  16. [Research progress of genetic engineering on medicinal plants].

    Science.gov (United States)

    Teng, Zhong-qiu; Shen, Ye

    2015-02-01

    The application of genetic engineering technology in modern agriculture shows its outstanding role in dealing with food shortage. Traditional medicinal plant cultivation and collection have also faced with challenges, such as lack of resources, deterioration of environment, germplasm of recession and a series of problems. Genetic engineering can be used to improve the disease resistance, insect resistance, herbicides resistant ability of medicinal plant, also can improve the medicinal plant yield and increase the content of active substances in medicinal plants. Thus, the potent biotechnology can play an important role in protection and large area planting of medicinal plants. In the development of medicinal plant genetic engineering, the safety of transgenic medicinal plants should also be paid attention to. A set of scientific safety evaluation and judgment standard which is suitable for transgenic medicinal plants should be established based on the recognition of the particularity of medicinal plants. PMID:26137675

  17. Analgesic activity of some Indian medicinal plants.

    Science.gov (United States)

    Malairajan, P; Geetha Gopalakrishnan; Narasimhan, S; Jessi Kala Veni, K

    2006-07-19

    In the present study of some of the Indian medicinal plants Sida acuta whole plant (Malvaeae), Stylosanthes fruticosa (whole plant) (Papilionaceae), Toona ciliata (heart wood) (Meliaceao), Bougainvilla spectabilis (leaves) (Nyctaginaceae), Ficus glomerata (bark, leaves) (Moraceae) and Polyalthia longifolia (leaves) (Annonaceae). The different plants were used in folklore medicine in the treatment of toothache and strengthening of gums, anthelmintic, kidney diseases, analgesic, anti-inflammatory, hepatoprotective, antihyperglycaemic, antihyperglycaemic and anticancer. The extract was prepared using powdered material with ethanol, concentrated under vacuo and were evaluated for analgesic activity by analgesiometer at three dose level (100, 300 and 500mg/kg). Analgesic activity was significant with Toona ciliata (heart wood) ethanolic extract when compared with other extracts and its activity was confirmed by tail immersion method. PMID:16647234

  18. TRADITIONAL MEDICINAL PLANTS: ANCIENT AND MODERN APPROACH

    OpenAIRE

    Sharma, S.C.; Ahmad, S. Aziz

    1992-01-01

    History of medicine and plants dates back to remote past when herbal treatment was the only answer to all kind of ailments. Nowadays, greater emphasis is again being laid to phytotherapy all over the world. Besides, cultivation-cum-setting up herbal gardens are also mooted on hills and plain areas as management of all kinds of diseases is possible through plant drugs sans toxicity.

  19. Flora medicinal de Chihuahua / Medicinal plants of Chihuahua State

    Scientific Electronic Library Online (English)

    Mario Humberto, Royo-Márquez; Alicia, Melgoza-Castillo; J. Santos, Sierra-Tristán.

    2013-08-01

    Full Text Available En México 10% de su vegetación está catalogada como medicinal. Al respecto, Chihuahua posee 20.2% de las plantas medicinales reconocidas en el país; sin embargo, no se ha publicado un listado a nivel estatal y se tienen pocos estudios etnobotánicos. Los objetivos del presente trabajo fueron revisar, [...] organizar y actualizar en una base de datos la información de las plantas medicinales de dicha entidad; las fuentes de información fueron literatura especializada y bases de datos botánicos con registros para el estado. Se documentaron 105 familias, 375 géneros, 605 especies y 44 infrataxa, de las cuales 14 se encuentran en riesgo de extinción según la NOM-059-SEMARNAT-2010. Las familias mejor representadas fueron: Asteraceae, Fabaceae y Euphorbiaceae, con 99, 51 y 27 especies, respectivamente. Las nativas correspondieron a 86% y las introducidas 14% (7.9% cultivadas). Las formas de crecimiento más abundantes resultaron ser las herbáceas latifoliadas, con 45.4%; los arbustos, con 18%; y los árboles, con 12.5%. Únicamente se presentan en un tipo de vegetación 32.1% de los taxa. En orden decreciente, la mayor riqueza correspondió al bosque de encino, con 56.5%, 51.2% al bosque de pino y 39.7% a los pastizales. En lo relativo al total de plantas medicinales se identificaron 1 090 usos, cuyos mayores porcentajes correspondieron a las utilizadas en los aparatos digestivo (37.8%) y genito-urinario (21.7%), así como en la piel y el tejido subcutáneo (32.3%). A fin de incrementar el conocimiento científico de las plantas medicinales, es necesario desarrollar más estudios etnobotánicos y análisis fitoquímicos. Abstract in english In Mexico, 10% of all the plants are classified as medicinal. Chihuahua possesses 20.2% of the species recognized as medicinal in the country; however, no state’s list of plants has been published, and ethnobotanical studies are scarce. The objectives of this paper were to review, organize and updat [...] e in a database the available information on the medicinal plants of the state. The sources of information were specialized literature and botanical data bases with registers for the entity. 105 families, 375 genera, 605 species, and 44 infrataxa were registered; 14 of the latter are endangered, according to NOM-059-SEMARNAT-2011. The most broadly represented families were Asteraceae, Fabaceae and Euphorbiaceae, with 99, 51 and 27 species, respectively. 86% of these are native, and 14% are introduced (7.9% are cultivated). The most abundant growths were broadleaf herbs (45.4%), shrubs (18%), and trees (12.5%). 32.1% of all the species belong to a single type of vegetation. The highest proportion (56.5%) corresponds to red oak forests, followed by 51.2% for pine forests, and 39.7% for grasslands. A total of 1 090 uses were found for the medicinal plants; the highest percentage, 37.8%, was for plants used for ailments of the digestive tract; 21.7% were used for the genitourinary tract, and 32.3%, for conditions of the skin and the subcutaneous tissue. In order to increase the scientific knowledge of the medicinal plants, further ethnobotanical studies and phytochemical analyses are required.

  20. Biological screening of Brazilian medicinal plants

    Directory of Open Access Journals (Sweden)

    Alves Tânia Maria de Almeida

    2000-01-01

    Full Text Available In this study, we screened sixty medicinal plant species from the Brazilian savanna ("cerrado" that could contain useful compounds for the control of tropical diseases. The plant selection was based on existing ethnobotanic information and interviews with local healers. Plant extracts were screened for: (a molluscicidal activity against Biomphalaria glabrata, (b toxicity to brine shrimp (Artemia salina L., (c antifungal activity in the bioautographic assay with Cladosporium sphaerospermum and (d antibacterial activity in the agar diffusion assay against Staphylococcus aureus, Escherichia coli, Bacillus cereus and Pseudomonas aeruginosa. Forty-two species afforded extracts that showed some degree of activity in one or more of these bioassays.

  1. ANTIMYCOTIC ACTIVITY OF SIX MEDICINAL PLANTS

    Directory of Open Access Journals (Sweden)

    VISHAL NARAYAN SHINDE

    2013-03-01

    Full Text Available The variable extracts of six medicinal plants prepared in 80% methanol and distilled water and were tested for their antimycotic activity against five different phytopathogenic fungi such as Alternaria carthami, Alternaria humicola, Fusarium oxysporum, Fusarium roseum, Pullularia pullulans. Among all the plant extracts, methanol extract of Lawsonia inermis and Hyptis sauvolens leaves were showed significant antifungal activity against targeted phytopathogens. Methanol extracts displayed maximum antifungal activity as compared to aqueous extracts. The antifungal activity revealed by these plants could be attributed to the synergetic effect of two or more chemical constituent.

  2. Biological screening of Brazilian medicinal plants

    Scientific Electronic Library Online (English)

    Tânia Maria de Almeida, Alves; Andréia Fonseca, Silva; Mitzi, Brandão; Telma Sueli Mesquita, Grandi; Elza de Fátima A, Smânia; Artur, Smânia Júnior; Carlos Leomar, Zani.

    2000-06-01

    Full Text Available In this study, we screened sixty medicinal plant species from the Brazilian savanna ("cerrado") that could contain useful compounds for the control of tropical diseases. The plant selection was based on existing ethnobotanic information and interviews with local healers. Plant extracts were screened [...] for: (a) molluscicidal activity against Biomphalaria glabrata, (b) toxicity to brine shrimp (Artemia salina L.), (c) antifungal activity in the bioautographic assay with Cladosporium sphaerospermum and (d) antibacterial activity in the agar diffusion assay against Staphylococcus aureus, Escherichia coli, Bacillus cereus and Pseudomonas aeruginosa. Forty-two species afforded extracts that showed some degree of activity in one or more of these bioassays.

  3. Studies in the complexes of U(IV) and Th(IV) with o-anisic acid, p-anisic acid and o-toluic acid

    International Nuclear Information System (INIS)

    U(IV) and Th(IV) complexes with ligands o-anisic acid, p-anisic acid and o-toluic acid have been isolated from U(OAc), and Th(OAc)4. Magnetic susceptibilities, IR and reflectance spectra of U(IV) and IR spectra of Th(IV) complexes have been studied to illustrate their structures. (auth.)

  4. The Medicinal Plants of Salt Range

    Directory of Open Access Journals (Sweden)

    Habib Ahmad

    2002-01-01

    Full Text Available Besides preserving mines of salts, minerals, fossils, archeological and cultural heritage; the mountainous terrain of the Salt Range also has immense potential for its biodiversity in the broadly overlapping ? the subtropical dry evergreen and the thorny subtropical semi deciduous? types of forest ecologies. Olea ferruginea, Acacia modesta, Reptonia buxifolia and Salvadora oleoides represent the apparent arboreal landscape of the terrain. More than 92 medicinal plants are not only used for curing ailments ranging from mild infections to the chronic ulcers but are also contributing a lot to the rural economy of the area. Floral diversity in general, the species of Litsea, Neolitsea and Colchicum in particular, are exposed to severe collection and the habitat loss pressures. Commonly known medicinal plants of the Salt Range, Punjab and their therapeutic uses are presented in this paper.

  5. Neutron activation analysis of medicinal plant extracts

    International Nuclear Information System (INIS)

    Instrumental neutron activation analysis was applied to the determination of the elements Br, Ca, Cl, Cs, Fe, K, La, Mg, Mn, Na, Rb and Zn in medicinal extracts obtained from Centella asiatica, Citrus aurantium L., Achyrolcline satureoides DC, Casearia sylvestris, Solano lycocarpum, Zingiber officinale Roscoe, Solidago microglossa and Stryphnondedron barbatiman plants. The elements Hg and Se were determined using radiochemical separation by means of retention of Se in HMD inorganic exchanger and solvent extraction of Hg by bismuth diethyldithiocarbamate solution. Precision and accuracy of the results were evaluated by analyzing biological reference materials. The therapeutic action of some elements found in plant extracts analyzed is briefly discussed. (author). 15 refs., 5 tabs

  6. Antimicrobial activity of some Iranian medicinal plants

    Directory of Open Access Journals (Sweden)

    Ghasemi Pirbalouti Abdollah

    2010-01-01

    Full Text Available The major aim of this study was to determine the antimicrobial activity of the extracts of eight plant species which are endemic in Iran. The antimicrobial activities of the extracts of eight Iranian traditional plants, including Hypericum scabrum, Myrtus communis, Pistachia atlantica, Arnebia euchroma, Salvia hydrangea, Satureja bachtiarica, Thymus daenensis and Kelussia odoratissima, were investigated against Escherichia coli O157:H7, Bacillus cereus, Listeria monocytogenes and Candida albicans by agar disc diffusion and serial dilution assays. Most of the extracts showed a relatively high antimicrobial activity against all the tested bacteria and fungi. Of the plants studied, the most active extracts were those obtained from the essential oils of M. communis and T. daenensis. The MIC values for active extract and essential oil ranged between 0.039 and 10 mg/ml. It can be said that the extract and essential oil of some medicinal plants could be used as natural antimicrobial agents in food preservation. .

  7. PRELIMINARY PHYTOCHEMISTRY AND PHENOLIC COMPOUNDS OF SOME FOLK MEDICINAL PLANTS

    OpenAIRE

    Koche D. K.; Suradkar S. S.; Kokate P. S.; Bhadange D. G.

    2012-01-01

    Several species of plants are being used as folk medicine by various tribal and local communities in India as well as all over the world since ancient days. Five medicinal plant species were analysed for their basic chemical composition that makes them medicinal. All the selected plants are found to contain phytochemicals like alkaloids, phenolics, flavonoids, tannins and saponin. It was observed that phenolic compounds are the most active drug content in modern herbal medicine. Therefore, th...

  8. A REVIEW ON ANTIULCER MEDICINAL PLANTS

    Directory of Open Access Journals (Sweden)

    Kamble Rahul Devidas

    2013-01-01

    Full Text Available Peptic ulcer is the most common gastrointestinal disorder in clinical practice. Peptic ulcer is a conglomerate of heterogeneous disorders, which manifests itself as a break in the lining of the gastrointestinal mucosa bathed by acid and/or pepsin. A number of drugs including proton pump inhibitors and H2 receptor antagonists are available for the treatment of peptic ulcer, but these drugs has shown incidence of relapses, side effects, and drug interactions. Thus the development of new antiulcer drugs and the search for novel molecules has been extended to herbal drugs that offer better protection and decreased relapse. Medicinal plants provide an effective and safer way in disease management. Many medicinal plants exhibit antiulcer activity and found useful in the treatment of peptic ulcer. In this review attempts have been made to know about some plants which may be used in treatment or prevention of peptic ulcer. Various plants like Nerium indicum, Ocimum sanctum, Argyreia speciosa, Bauhinia purpurea, Benincasa hispida and Croton zambesicus proved active in antiulcer therapy.

  9. MAPS Database: Medicinal plant Activities, Phytochemical and Structural Database

    OpenAIRE

    Ashfaq, Usman Ali; Mumtaz, Arooj; qamar, Tahir ul; Fatima, Tabeer

    2013-01-01

    Drug development from natural sources is an important and fast developing area. Natural sources (plants) have been used to cure a range of diseases for Thousands of years. Different online medicinal plant databases provide information about classifications, activities, phytochemicals and structure of phytochemicals in different formats. These databases do not cover all aspects of medicinal plants. MAPS (Medicinal plant Activities, Phytochemicals & structural database) has been constr...

  10. Plant-antivenom: Database of anti-venom medicinal plants

    Scientific Electronic Library Online (English)

    Saulo França, Amui; Renato David, Puga; Andreimar Martins, Soares; Silvana, Giuliatti.

    2011-01-15

    Full Text Available Plant-antivenom is a computational Websystem about medicinal plants with anti-venom properties. The system consists of a database of these plants, including scientific publications on this subject and amino acid sequences of active principles from venomous animals. The system relates these data allo [...] wing their integration through different search applications. For the development of the system, the first surveys were conducted in scientific literature, allowing the creation of a publication database in a library for reading and user interaction. Then, classes of categories were created, allowing the use of tags and the organization of content. This database on medicinal plants has information such as family, species, isolated compounds, activity, inhibited animal venoms, among others. Provision is made for submission of new information by registered users, by the use of wiki tools. Content submitted is released in accordance to permission rules defined by the system. The database on biological venom protein amino acid sequences was structured from the essential information from National Center for Biotechnology Information (NCBI). Plant-antivenom's interface is simple, contributing to a fast and functional access to the system and the integration of different data registered on it. Plant-antivenom system is available on the Internet at http://gbi.fmrp.usp.br/plantantivenom.

  11. Antiradical efficiency of 20 selected medicinal plants.

    Science.gov (United States)

    Kamal, Raka; Yadav, Sunita; Mathur, Manas; Katariya, Pawan

    2012-01-01

    The antioxidant system of a plant comprises a group of chemicals that are highly diverse in their sources, effects and uses. These antioxidants are capable of contracting and damaging free radicals. This investigation deals with a screening and comparison of the antioxidant activities of 20 selected medicinal plants and their parts, individually and in combination with vitamins A, C or E, using the DPPH radical scavenging method. Phyllanthus emblica L., Santalum album L., Syzygium cumini L. and Trigonella foenum-graecum L. presented highly significant antiradical efficiency (AE) singly and in combination with either vitamin A, C or E. Further, Curcuma longa L., Momordica charantia L., S. cumini, T. foenum-graecum, Moringa oleifera Lam and S. album have also shown fairly significant AE in a vitamin combination dose of 0.001 mM concentration. PMID:22010999

  12. Multimedia-based Medicinal Plants Sustainability Management System

    CERN Document Server

    Omogbadegun, Zacchaeus; Ayo, Charles; Mbarika, Victor; Omoregbe, Nicholas; Otofia, Efe; Chieze, Frank

    2011-01-01

    Medicinal plants are increasingly recognized worldwide as an alternative source of efficacious and inexpensive medications to synthetic chemo-therapeutic compound. Rapid declining wild stocks of medicinal plants accompanied by adulteration and species substitutions reduce their efficacy, quality and safety. Consequently, the low accessibility to and non-affordability of orthodox medicine costs by rural dwellers to be healthy and economically productive further threaten their life expectancy. Finding comprehensive information on medicinal plants of conservation concern at a global level has been difficult. This has created a gap between computing technologies' promises and expectations in the healing process under complementary and alternative medicine. This paper presents the design and implementation of a Multimedia-based Medicinal Plants Sustainability Management System addressing these concerns. Medicinal plants' details for designing the system were collected through semi-structured interviews and databas...

  13. Antioxidant Capacity of Macaronesian Traditional Medicinal Plants

    Directory of Open Access Journals (Sweden)

    Lucélia Tavares

    2010-04-01

    Full Text Available The use of many traditional medicinal plants is often hampered by the absence of a proper biochemical characterization, essential to identify the bioactive compounds present. The leaves from five species endemic to the Macaronesian islands with recognized ethnobotanical applications were analysed: Apollonias barbujana (Cav. Bornm., Ocotea foetens (Ainton Baill, Prunus azorica (Mouill. Rivas-Mart., Lousã, Fern. Prieto, E. Días, J.C. Costa & C. Aguiar, Rumex maderensis Lowe and Plantago arborescens Poir. subsp. maderensis (Dcne. A. Hans. et Kunk.. Since oxidative stress is a common feature of most diseases traditionally treated by these plants, it is important to assess their antioxidant capacity and determine the molecules responsible for this capacity. In this study, the antioxidant capacity of these plants against two of the most important reactive species in human body (hydroxyl and peroxyl radicals was determined. To trace the antioxidant origin total phenol and flavonoid contents as well as the polyphenolic profile and the amount of trace elements were determined. There was a wide variation among the species analysed in what concerns their total leaf phenol and flavonoid contents. From the High Performance Liquid Chromatography (HPLC electrochemically detected peaks it was possible to attribute to flavonoids the antioxidant capacity detected in A. barbujana, O. foetens, R. maderensis and P. azorica extracts. These potential reactive flavonoids were identified for A. barbujana, R. maderensis and P. azorica. For R. maderensis a high content (7 mg g-1 dry weight of L-ascorbic acid, an already described antioxidant phytomolecule, was found. A high content in selenomethionine (414.35 ?g g-1 dry weight was obtained for P. arborescens subsp. maderensis extract. This selenocompound is already described as a hydroxyl radical scavenger is reported in this work as also possessing peroxyl radical scavenging capacity. This work is a good illustration of different phytomolecules (flavonoids, organic acids and selenocompounds, presents in leaves of the five traditional medicinal plants endemic to Macaronesia, all exhibiting antioxidant properties.

  14. Radio protective effects of some medicinal plants

    International Nuclear Information System (INIS)

    Many plants are known to have beneficial therapeutic effects as noted in the traditional Indian system of medicine, Ayurveda and used since time immemorial for curing diseases. Even today, nearly 70% of the world's population is dependent on plants for handling their health related problems and plants have been utilized successfully for the treatment of free radical-mediated diseases in human such as Rheumatoid arthritis, Atherosclerosis, Cancer, Alzheimer's disease, Parkinson's disease, aging and several other conditions including inflammatory diseases. Plant extracts eliciting radio protective efficacy contain a plethora of compounds including antioxidants, immunostimulants, cell proliferation stimulators, anti-inflammatory and antimicrobial agent, some of which may act in isolation as well as in combination with other constituents from the same plants. Glycyrrhiza glabra, Allium sepa, Allium sativum, Aloe arborescens, Amaranthus paniculatus, Curcuma longa, Moringa olefera and Syzygium cumini are some important radio protective plants. Alium sativum has been reported to possess antioxidant antimicrobial, antitumor, antimutagenic and anti-inflammatory properties. Aloe arborescens acts as a cell proliferate, healer and allergy reducer. Amaranthus paniculatus is used for purifying blood and treating scrofulous sores. Curcuma longa is widely used in antitumor and antibacterial activities. Leaf extract of Moringa oleifera is significantly used in nervous debility and healing of wound. Chlorella is well known nutrient dense superfood that contains 60% protein, 18 amino acids (including all the essential amino acids), more than 20 vitamins and minerals. Chlorell has been used to treat cancer and also protect the body from the effects of cancer radiation treatment due to its chlorophyll in abundance level. However they have little attention for their radio protective as well as antioxidant. There is an urgent need to develop newer, more efficient and reliable bioassays for large scale rapid evaluation of radio protective efficacy of plant extracts. (author)

  15. IMMUNOSTIMULANT EFFECT OF MEDICINAL PLANTS ON FISH

    Directory of Open Access Journals (Sweden)

    Pandey Govind

    2012-03-01

    Full Text Available Fishes not only play an important role in the demand of food for humans but they have also emerged as major model organisms for different biomedical researches. A number of experiments with the use of several drugs have been conducted in fish. Diseases in fish caused by bacteria are most widespread. Antibiotics are frequently used to control fish diseases caused by bacteria, but there is an increasing risk of developing antibiotic resistant strains of bacteria. The medicinal plants can act as immunostimulants, conferring early activation to the non-specific defense mechanisms of fish and elevating the specific immune response. The herbs contain many immunologically active components such as polysaccharides, organic acids, alkaloids, glycosides and volatile oils, which can enhance immune functions. Recently, there has been increased interest in the immune stimulating function of some herbs in aquaculture. The non-specific immune functions such as bacteriolytic activity and leukocyte function of fish have been improved by some herbs. Henceforth, this article elucidates certain herbs (medicinal plants which have been shown experimentally as well as clinically to possess immunostimulant effects in fish, thereby treating different fish diseases.

  16. Some Plants used in Ayurvedic and Homoeopathic Medicine

    Directory of Open Access Journals (Sweden)

    R.P.Joshi

    2013-05-01

    Full Text Available Traditional medicines are used by about 60% of the world’s population. These are used for primary health care, not only in rural areas of developing nations but they are also used in the developed countries where modern medicine are pre dominantly used. In the western world the use of medicinal herbs is continuously growing, approximately 40% of the population is using herbs for medical illness due to increased incidences of adverse effects of allopathic medicine. There are about 45000 plant species in India, Eastern Himalayas, Western Ghats and Andman and Nicobar Islands are the hot spot for medicinal plants. Officially documented plants with medicinal potential are 3000 but traditional practitioner use more than 6000. Seventy percent of the population in the rural India is dependent on the ayurvedic system of medicine. Most of the drugs used in modern medicine and ancient Indian medicinal system are of plant origin. Beside plants many minerals, salts and animal products are used in Ayurvedic medicines. Homoeopathy originated in west, German physician Samuel Hanemann was the father of homoeopathy (1796, the homeopathic remedies are prepared by successive dilution followed by shaking forcefully. Homoeopathy uses animal, plant, mineral, and synthetic substances in its remedies. Arsenicum album (arsenic oxide, Natrum muriaticum (sodium chloride, opium (plant, and thyroidinum (thyroid hormone are some of the homoeopathic medicines extracted from different sources.

  17. Potential anti-dengue medicinal plants: a review

    OpenAIRE

    Abd Kadir, Siti Latifah; Yaakob, Harisun; Mohamed Zulkifli, Razauden

    2013-01-01

    Dengue fever causes mortality and morbidity around the world, specifically in the Tropics and subtropic regions, which has been of major concern to governments and the World Health Organization (WHO). As a consequence, the search for new anti-dengue agents from medicinal plants has assumed more urgency than in the past. Medicinal plants have been used widely to treat a variety of vector ailments such as malaria. The demand for plant-based medicines is growing as they are generally considered ...

  18. Initial Studies on Alkaloids from Lombok Medicinal Plants

    Directory of Open Access Journals (Sweden)

    John B. Bremner

    2001-01-01

    Full Text Available Initial investigation of medicinal plants from Lombok has resulted in the collection of 100 plant species predicted to have antimicrobial, including antimalarial, properties according to local medicinal uses. These plants represent 49 families and 80 genera; 23% of the plants tested positively for alkaloids. Among the plants testing positive, five have been selected for further investigation involving structure elucidation and antimicrobial testing on the extracted alkaloids. Initial work on structural elucidation of some of the alkaloids is reported briefly.

  19. Antimicrobial activity of some medicinal plants from Ghana.

    Science.gov (United States)

    Konning, G H; Agyare, C; Ennison, B

    2004-01-01

    The results of a preliminary antimicrobial screening of the methanol extracts of Aframomum melegueta, Piper guineense, Xylopia aethiopica, Zingiber officinale, medicinal plants of Ghana, are reported. PMID:14693222

  20. Color and Edge Histograms Based Medicinal Plants' Image Retrieval

    Directory of Open Access Journals (Sweden)

    Basavaraj S. Anami

    2012-08-01

    Full Text Available In this paper, we propose a methodology for color and edge histogram based medicinal plants image retrieval. The medicinal plants are divided into herbs, shrubs and trees. The medicinal plants are used in ayurvedic medicines. Manual identification of medicinal plants requires a priori knowledge. Automatic recognition of medicinal plants is useful. We have considered medicinal plant species, such as Papaya, Neem, Tulasi and Aloevera are considered for identification and retrieval. The color histograms are obtained in RGB, HSV and YCbCr color spaces. The number of valleys and peaks in the color histograms are used as features. But, these features alone are not helpful in discriminating plant images, since majority plant images are green in color. We have used edge and edge direction histograms in the work to get edges in the stem and leafy parts. Finally, these features are used in retrieval of medicinal plant images. Absolute distance, Euclidean distance and mean square error, similarity distance measures are deployed in the work. The results show an average retrieval efficiency of 94% and 98% for edge and edge direction features respectively.

  1. COASTAL MEDICINAL PLANTS ALONG PALK STRAIT : A SURVEY

    Directory of Open Access Journals (Sweden)

    Uma pandi .M

    2010-11-01

    Full Text Available India has one of the richest plant medical cultures in the world. Millions of rural house holds use medicinal plants in a self-help mode. In the present study the survey is made on the coastal medicinal plants from S.P. Pattinam to Karangadu along Palk Strait. A total number of around thirty four plants such as Acacia arabica, Acorus calamus, Adhatoda vasica, Aloe vera, Alpinia galangal, Anisomeles malabarica, Cardiospermam halicacabam, Cassia juvanica, Cassia obtuse, Citrus limon, Coleus aromaticus, Cynodon dactylon, Daemia extensa, Datura metel, Eclipta alba, Enicostemma littorale, Evolvulus alsinoides etc from 24 families were recorded as a home based medicinal plants.

  2. Ethnomedicinal Evaluation of Medicinal Plants Used against Gastrointestinal Complaints

    OpenAIRE

    Tariq, Akash; Mussarat, Sakina; Adnan, Muhammad; Abd_Allah, E. F.; Hashem, Abeer; Alqarawi, Abdulaziz Abdullah; Ullah, Riaz

    2015-01-01

    Aim of the present study was to document ethnomedicinal plants used against gastrointestinal complaints in five selected remote regions of Pakistan and to select potential medicinal plants for further in vitro and in vivo investigation. Data on ethnomedicinal plants and ethnographic profile of respondents was documented using semistructured questionnaires. The present study revealed utilization of 52 medicinal plants for the treatment of different gastrointestinal infections in studied region...

  3. Antioxidant activity of some Turkish medicinal plants.

    Science.gov (United States)

    Karadeniz, A; Çinbilgel, I; Gün, S ?; Çetin, A

    2015-12-01

    DPPH, superoxide and nitric oxide radical scavenging activities and total phenolic content (TPC) of some less known plants, distributed in Burdur-Antalya provinces and consumed both as food and for the medicine, Asplenium ceterach L. (golden herb), Valeriana dioscoridis Sm. (valerian), Doronicum orientale Hoffm. (tiger herb), Cota pestalozzae (Boiss.) Boiss. (camomile), Eremurus spectabilis M. Bieb. (foxtail lily), Asphodeline lutea (L.) Rchb. (asphodel) and Smyrnium connatum Boiss. and Kotschy (hemlock) were investigated. As a result, the highest 2,2-diphenyl-1-picril hydrazyl (DPPH) radical scavenging activity was determined in C. pestalozzae extract (IC50 = 18.66 ?g mL(- 1)), the highest superoxide and nitric oxide radical scavenging activity was determined in A. ceterach extract (IC50 = 145.17 and 372.03 ?g mL(- 1)). The highest TPC was determined in A. ceterach extract (59,26 ?g mL(- 1)) as gallic acid equivalent. Further bioactivity and phytochemistry studies on these plants may enlighten new drug discovery researches. PMID:25649168

  4. MEDICINAL PLANT WEALTH OF ANDHRA PRADESH – PART I

    OpenAIRE

    Hemadri, Koppula; Sarma, C. Raja Rajeswari; Rao, Swahari Sasibushana

    1987-01-01

    This paper presents the Medical Plant Wealth of Andhra Pradesh based on the results of Medico – Ethno – Botanical exploration undertaken during the last fourteen years (1971 – 72 till the end of 1984). In all, 117 well known medicinal plants widely used in Ayurveda, Siddha and other systems of Medicine are enumerated here.

  5. Gitksan medicinal plants-cultural choice and efficacy

    Directory of Open Access Journals (Sweden)

    Johnson Leslie

    2006-06-01

    Full Text Available Abstract Background The use of plants for healing by any cultural group is integrally related to local concepts of the nature of disease, the nature of plants, and the world view of the culture. The physical and chemical properties of the plants themselves also bear on their selection by people for medicines, as does the array of plants available for people to choose from. I examine use of medicinal plants from a "biobehavioral" perspective to illuminate cultural selection of plants used for medicine by the Gitksan of northwestern British Columbia, Canada. Methods Consultant consensus, "intercultural consensus", independent use of the same plants by other cultural groups, and phytochemistry and bioassay results from the literature, were employed in analysis of probable empirical efficacy of plant uses. Results 70% of 37 Gitksan medicinal plants were used similarly by other cultures where direct diffusion is not known to have occurred; eleven plants, including the eight most frequently mentioned medicinal plants, also show active phytochemicals or bioassays indicating probable physiologically based therapeutic effects. Conclusion Analysis of intercultural consensus revealed that the majority of cultures in the British Columbia region within the plant ranges use the same plants, or closely related species, in similar ways. The rigor of this analysis is effected by the lack of consistent data on all taxa of interest for all cultures within the region.

  6. Systematic organization of medicinal plant information: a monograph template proposal

    Scientific Electronic Library Online (English)

    Ana C.B., Carvalho; Ligia A., Santos; Dâmaris, Silveira.

    2014-01-01

    Full Text Available The use of medicinal plants in Brazil is widespread and is supported by public policies; it has the objective of providing the population with safe and effective herbal medicines of adequate quality. An action in these policies is to develop medicinal plant monographs to gather published information [...] and decide which medicinal plants should be financed by the Brazilian government and distributed by the public health system. Currently, the monographs published worldwide do not present unified information regarding medicinal plants, and generally, they do not cover enough requirements for herbal medicine registration. The aim of this study is to develop a monograph model with standardized information not only about botany, agronomy, quality control, safety, and efficacy but also about relating regulatory aspects that support herbal medicine regulation. The development of standardized monographs favors the fast authorization and distribution of herbal medicines in the public system. The model also points out the lacking studies that should be carried out to supplement the necessary regulatory information of medicinal plants.

  7. Systematic organization of medicinal plant information: a monograph template proposal

    Directory of Open Access Journals (Sweden)

    Ana C.B. Carvalho

    2014-01-01

    Full Text Available The use of medicinal plants in Brazil is widespread and is supported by public policies; it has the objective of providing the population with safe and effective herbal medicines of adequate quality. An action in these policies is to develop medicinal plant monographs to gather published information and decide which medicinal plants should be financed by the Brazilian government and distributed by the public health system. Currently, the monographs published worldwide do not present unified information regarding medicinal plants, and generally, they do not cover enough requirements for herbal medicine registration. The aim of this study is to develop a monograph model with standardized information not only about botany, agronomy, quality control, safety, and efficacy but also about relating regulatory aspects that support herbal medicine regulation. The development of standardized monographs favors the fast authorization and distribution of herbal medicines in the public system. The model also points out the lacking studies that should be carried out to supplement the necessary regulatory information of medicinal plants.

  8. CATHARANTHUS ROSEUS: ORNAMENTAL PLANT IS NOW MEDICINAL BOUTIQUE

    Directory of Open Access Journals (Sweden)

    M Santhosh Aruna,

    2015-05-01

    Full Text Available India possesses a rich biodiversity of the medicinal plants that were still not explored completely. Catharanthus roseus is native to the Indian Ocean island of Madagascar. This herb is now common in many tropical and subtropical regions worldwide, including the southern United States. It is a popular ornamental plant found in gardens and homes across the warmer parts of the world. The need for the novel pharmaceutical products out from the plant has attained a great interest in the present research world due to the cost and the higher side effects that are associated with the chemically manufactured drugs. Catharanthus roseus, which is a potent medicinal plant many of the pharmacological actions. That is used to treat many of the fatal diseases. Alkaloids were the major phytochemical constituent of the above medicinal plant and have different types possessing various medicinal uses. This review highlights the marvelous properties of this plant.

  9. Collection and conservation of medicinal and aromatic plants resources

    OpenAIRE

    Abraham, Z.

    2011-01-01

    (Abstract selected from presentation in National Conference on Biodiversity of Medicinal and Aromatic Plants: Collection, Characterization and Utilization, held at Anand, India during November 24-25, 2010)Plant genetic resources have made substantial contributions to the domestication, utilization and improvement of all kinds of crops including medicinal and aromatic plants. Collection, characterization and  their efficient utilization are keys to efficient management of any kind of genetic r...

  10. Effects of gamma irradiation on antioxidants of medicinal plants

    International Nuclear Information System (INIS)

    The antioxidant effect of water extracts from irradiated medicinal plants on inhibition of lipid peroxidation in human plasma was examined. The results presented herein indicate that crude extracts from 29 kinds, 31 extracts, of medicinal plants, irradiated at 10 and 25 kilo gray. showed no significant change in inhibition of lipid peroxidation in plasma induced by gamma irradiation (p<0.05). It also found that extraction yields in some irradiated plants were increased

  11. NEW DIMENSION OF MEDICINAL PLANTS AS ANIMAL FEED

    OpenAIRE

    M. A. TIPU, M. S. AKHTAR, M. I. ANJUM1 AND M. L. RAJA

    2006-01-01

    The medicinal plants and herbs have been used for many years in the treatment of various diseases in animals and human beings. Now-a-days, utilization of these medicinal plants is increasing. These are used in animal feed as the growth promoters. Due to prohibition of most of the antimicrobial growth promoters in animal feed because of their residual effects, plant extracts are becoming more popular. They act as antibacterial, antioxidant, anticarcinogenic, antifungal, analgesic, insecticidal...

  12. Distribution of Phenolics in Various Malaysian Medicinal Plants

    OpenAIRE

    Amid, A.; A.A. Barkat; P. Jamal

    2010-01-01

    Phenolics, which are widely distributed in plant kingdom, appear to have desirable medicinal properties and play a major role in both plant and animal health. Some have been reported to be antitumor agents and to exhibit antiviral and antimicrobial activities, hypotensive effects and antioxidant properties. These compounds, either as isolates or in conjunction with other compounds, may be used for various health benefits. In this study, forty types of Malaysian medicinal plants were examined ...

  13. MEDICINAL PLANTS OF RAJASTHAN (INDIA) WITH ANTIDIABETIC POTENTIAL

    OpenAIRE

    Batra Shikha; Nagori Badri Prakash; Batra Nikhil

    2011-01-01

    Rajasthan has a rich heritage of traditional system of medicine and many medicinally useful plants are found growing wildly because of vast area and variety of agro-climatic conditions. These plants are being used for the treatment of many human ailments including diabetes. Plants that are specifically employed for the treatment of diabetes are Acacia nilotica, Acacia senegal, Aegle marmelos, Calotropis procera, Capparis deciduas, Cassia auriculata, Cassia sophera, Cayratia trifolia, Cyamopsi...

  14. Are Medicinal Plants Polluted with Phthalates?

    Directory of Open Access Journals (Sweden)

    Soodabeh Saeidnia

    2013-05-01

    Full Text Available Phthalic acid esters (PAEs have been employed in polymer materials as a plasticizer to form them more flexible, adhesive, and soluble. These compounds are mainly used in paints, varnishes, personal cares, cosmetics, paper coatings, and adhesives even in bottled waters, shampoo, body deodorant, hairspray, and gels. Phthalates are able to possess remarkable toxic variations depending on their structures. So far, Di-(2-EthylHexyl Phthalate DEHP and Di-n- Butyl Phthalate DBP have been found to cause reproductive and developmental toxicities. The U.S. Environmental Protection Agency (EPA classified DEHP as probable human carcinogen. To the best of our knowledge, phthalates showed diverse toxicity profiles according to their structures in the liver, kidneys, thyroid, and testes, which are involved in general toxicity. Furthermore, they are introduced as hormonally-active agents, because they can interfere with the endocrine system in human. Incidence of developmental abnormalities (like skeletal malformations and cleft palate, and undescended testes, lowering testes weight and anogenital distance seems increasing via high exposure to phthalate metabolites. Although, increasing the capacity for phthalate free plasticizer productions is the first step to restrict the distribution of these toxic manmade compounds, finding the new ways for phthalate absorption from the soil in agricultural fields may have benefits. Also, evaluation and examination of diverse sources of medicinal and food plants to determine the level of phthalate accumulation in their organs are extremely recommended to avoid creating toxicity particularly in reproductive systems.

  15. Are medicinal plants polluted with phthalates?

    Science.gov (United States)

    Saeidnia, Soodabeh; Abdollahi, Mohammad

    2013-01-01

    Phthalic acid esters (PAEs) have been employed in polymer materials as a plasticizer to form them more flexible, adhesive, and soluble. These compounds are mainly used in paints, varnishes, personal cares, cosmetics, paper coatings, and adhesives even in bottled waters, shampoo, body deodorant, hairspray, and gels. Phthalates are able to possess remarkable toxic variations depending on their structures. So far, Di-(2-EthylHexyl) Phthalate DEHP and Di-n- Butyl Phthalate DBP have been found to cause reproductive and developmental toxicities. The U.S. Environmental Protection Agency (EPA) classified DEHP as probable human carcinogen. To the best of our knowledge, phthalates showed diverse toxicity profiles according to their structures in the liver, kidneys, thyroid, and testes, which are involved in general toxicity. Furthermore, they are introduced as hormonally-active agents, because they can interfere with the endocrine system in human. Incidence of developmental abnormalities (like skeletal malformations and cleft palate, and undescended testes, lowering testes weight and anogenital distance) seems increasing via high exposure to phthalate metabolites. Although, increasing the capacity for phthalate free plasticizer productions is the first step to restrict the distribution of these toxic manmade compounds, finding the new ways for phthalate absorption from the soil in agricultural fields may have benefits. Also, evaluation and examination of diverse sources of medicinal and food plants to determine the level of phthalate accumulation in their organs are extremely recommended to avoid creating toxicity particularly in reproductive systems. PMID:23718122

  16. Trace elements in Malaysian medicinal plants

    International Nuclear Information System (INIS)

    Elemental content of twenty medicinal plants used as tonic and for treatment of diabetes and sinusitis were determined by INAA and XRF. Elemental determination was carried out in the raw samples, residues after boiling and the water soluble fractions. Samples were irradiated in TRIGA MkII reactor and counted using HPGe detector coupled to Personal Computer Analyzer (PCA) system. Bowen's Kale, NBS Pine Needles, NBS citrus Leaves SRM were analysed to check the accuracy of the techniques used. Twenty elements were determined by both NAA and XRF. Arsenic was only detected in Labisia pothoina and Dracontomelon dao with a concentrations of 0.40 mg/kg and 0.60 mg/kg respectively. Antimony was found in eleven samples with a concentration of <0.20 mg/kg. Al, Br, Ca, Cl, K, Mn, Na and Rb were detected in all samples whereas Mg and Zn were present in all samples except Cinnamomum sp. Highest concentration of Br(190 mg/kg), Cl (11805 mg/kg), Co(0.50 mg/kg), Fe(1642 mg/kg), K(36788 mg/kg), Mn (325 mg/kg), Na(126 mg/kg), Rb(197 mg/kg), Sc(0.18 mg/kg) and Zn(3551 mg/kg) were observed in the tuber of Lasia aculeata. Less than 70% and 50% of the elements contained in Callicarpa longifolia and Eurycoma longifolia were obtained respectively from water by boiling. (author). 10 refs., 4 tabs

  17. A Systematic Review of Iran's Medicinal Plants With Anticancer Effects.

    Science.gov (United States)

    Asadi-Samani, Majid; Kooti, Wesam; Aslani, Elahe; Shirzad, Hedayatollah

    2016-04-01

    Increase in cases of various cancers has encouraged the researchers to discover novel, more effective drugs from plant sources. This study is a review of medicinal plants in Iran with already investigated anticancer effects on various cell lines. Thirty-six medicinal plants alongside their products with anticancer effects as well as the most important plant compounds responsible for the plants' anticancer effect were introduced. Phenolic and alkaloid compounds were demonstrated to have anticancer effects on various cancers in most studies. The plants and their active compounds exerted anticancer effects by removing free radicals and antioxidant effects, cell cycle arrest, induction of apoptosis, and inhibition of angiogenesis. The investigated plants in Iran contain the compounds that are able to contribute effectively to fighting cancer cells. Therefore, the extract and active compounds of the medicinal plants introduced in this review article could open a way to conduct clinical trials on cancer and greatly help researchers and pharmacists develop new anticancer drugs. PMID:26297173

  18. Ethnopharmacological survey of wild medicinal plants in Showbak, Jordan.

    Science.gov (United States)

    Al-Qura'n, S

    2009-05-01

    Two main research questions are framing this investigation: (1) the main taxa of the medicinal importance value altered the Showbak forest stand and species composition? (2) The most safe species and what are the toxic ones (unsafe). These two research questions are the vital ones to draw a clear image about the wild medicinal plants of this investigated area of Showbak region in Jordan. 79 wild medicinal plant species were investigated in this study which are used in traditional medication for the treatment of various diseases. Most of the locals interviewed dealt with well-known safe medicinal plants such as Aaronsohnia factorovskyi Warb. et Eig., Achillea santolina L., Adiantum capillus-veneris L., Artemisia herba-alba L., Ceratonia siliqua L., Clematis recta L., Herniaria hirsuta L., Malva neglecta Wallr., Rosmarinus officinalis L., Ruta chalepensis L., Salvia triloba L., Sarcopoterium spinosa (L.) Spach., Thymbra capitata (L.) Hof, and Urginea maritima Barker. Many of the wild medicinal plants investigated were toxic and needed to be practiced by practitioners and herbalists rather than the local healers. These plants include Calotropis procera Willd R.Br., Citrullus colocynthis (L.) Sch., Datura stramonium L., Digitalis purpurea L., Ecballium elaterium (L.) A.Rich., Euphorbia helioscopia L., Euphorbia tinctoria Boiss., Glaucium corniculatum (L.) Curt., Hyoscyamus aureus L., Mandragora officinarum L., Nerium oleander L., Ricinus communis L., Solanum nigrum L., Withania somnifera (L.) Dunel. The conservation of medicinal plants and natural resources is becoming increasingly important, so this research is trying to collect information from local population concerning the use of medicinal plants in Showbak; identify the most important specie; determine the relative importance value of the species and calculate the informant consensus factor (ICF) for the medicinal plants. Obtaining results is relied on the interviewee's personal information and the medicinal use of specific plants. PMID:19429338

  19. The microbiome of medicinal plants: diversity and importance for plant growth, quality and health.

    Science.gov (United States)

    Köberl, Martina; Schmidt, Ruth; Ramadan, Elshahat M; Bauer, Rudolf; Berg, Gabriele

    2013-01-01

    Past medicinal plant research primarily focused on bioactive phytochemicals, however, the focus is currently shifting due to the recognition that a significant number of phytotherapeutic compounds are actually produced by associated microbes or through interaction with their host. Medicinal plants provide an enormous bioresource of potential use in modern medicine and agriculture, yet their microbiome is largely unknown. The objective of this review is (i) to introduce novel insights into the plant microbiome with a focus on medicinal plants, (ii) to provide details about plant- and microbe-derived ingredients of medicinal plants, and (iii) to discuss possibilities for plant growth promotion and plant protection for commercial cultivation of medicinal plants. In addition, we also present a case study performed both to analyse the microbiome of three medicinal plants (Matricaria chamomilla L., Calendula officinalis L., and Solanum distichum Schumach. and Thonn.) cultivated on organically managed Egyptian desert farm and to develop biological control strategies. The soil microbiome of the desert ecosystem was comprised of a high abundance of Gram-positive bacteria of prime importance for pathogen suppression under arid soil conditions. For all three plants, we observed a clearly plant-specific selection of the microbes as well as highly specific diazotrophic communities that overall identify plant species as important drivers in structural and functional diversity. Lastly, native Bacillus spec. div. strains were able to promote plant growth and elevate the plants' flavonoid production. These results underline the numerous links between the plant-associated microbiome and the plant metabolome. PMID:24391634

  20. The microbiome of medicinal plants: diversity and importance for plant growth, quality and health

    Directory of Open Access Journals (Sweden)

    MartinaKöberl

    2013-12-01

    Full Text Available Past medicinal plant research primarily focused on bioactive phytochemicals, however the focus is currently shifting due to the recognition that a significant number of phytotherapeutic compounds are actually produced by associated microbes or through interaction with their host. Medicinal plants provide an enormous bioresource of potential use in modern medicine and agriculture, yet their microbiome is largely unknown. The objective of this review is i to introduce novel insights into the plant microbiome with a focus on medicinal plants, ii to provide details about plant- and microbe-derived ingredients of medicinal plants, and iii to discuss possibilities for plant growth promotion and plant protection for commercial cultivation of medicinal plants. In addition, we also present a case study performed both to analyse the microbiome of three medicinal plants (Matricaria chamomilla L., Calendula officinalis L. and Solanum distichum Schumach. and Thonn. cultivated on organically managed Egyptian desert farm and to develop biological control strategies. The soil microbiome of the desert ecosystem was comprised of a high abundance of Gram-positive bacteria of prime importance for pathogen suppression under arid soil conditions. For all three plants, we observed a clearly plant-specific selection of the microbes as well as highly specific diazotrophic communities that overall identify plant species as important drivers in structural and functional diversity. Lastly, native Bacillus spec. div. strains were able to promote plant growth and elevate the plants’ flavonoid production. These results underline the numerous links between the plant-associated microbiome and the plant metabolome.

  1. Update on Medicinal Plants with Potency on Mycobacterium ulcerans

    Science.gov (United States)

    Tsouh Fokou, Patrick Valere; Nyarko, Alexander Kwadwo; Appiah-Opong, Regina; Tchokouaha Yamthe, Lauve Rachel; Ofosuhene, Mark; Boyom, Fabrice Fekam

    2015-01-01

    Mycobacterium ulcerans disease has been a serious threat for people living in rural remote areas. Due to poverty or availability of traditional medicine these populations rely on herbal remedies. Currently, data on the anti-Mycobacterium ulcerans activity of plants, so far considered community-based knowledge, have been scientifically confirmed, concomitantly with some medicinal plants used to treat infectious diseases in general. Products derived from plants usually responsible for the biological properties may potentially control Mycobacterium ulcerans disease; numerous studies have aimed to describe the chemical composition of these plant antimicrobials. Thus, the present work provides the first compilation of medicinal plants that demonstrated inhibitory potential on Mycobacterium ulcerans. This work shows that the natural products represent potential alternatives to standard therapies for use as curative medicine for Mycobacterium ulcerans disease. PMID:26779539

  2. Historical versus contemporary medicinal plant uses in Ghana

    DEFF Research Database (Denmark)

    Soelberg, Jens; Asase, A; Akwetey, G; Jäger, A K

    2015-01-01

    ETHNOPHARMACOLOGICAL RELEVANCE: Three extraordinary, historical documents stemming from observations made in 1697, 1803 and 1817 quote medicinal plant uses among the Fante, Ga and Ashanti people of present-day Ghana, and can be linked to original botanical specimens in European herbaria. This...... provides a unique opportunity to gain insight to the historical materia medica of Ghana and compare this to contemporary medicinal plant uses. By critical literary and taxonomic review, the present study (re-)establishes the earliest known history of many important Ghanaian medicinal plants, and assesses...... the scale of change and loss of medicinal plant knowledge in Ghana over time. The study provides the foundation to reconstruct lost or discontinued Ghanaian plant uses in local or ethnopharmacological contexts. MATERIALS AND METHODS: Historical botanical specimens were located in the herbaria of...

  3. Cloning of medicinal plants through tissue culture--a review.

    Science.gov (United States)

    Chaturvedi, H C; Jain, Madhu; Kidwai, N R

    2007-11-01

    In order to have standardized formulations, the chemical constituents from plants and their parts are required to be uniform both qualitatively and quantitatively. Furthermore, an ever increasing demand of uniform medicinal plants based medicines warrants their mass cloning through plant tissue culture strategy. A good number of medicinal plants have been reported to regenerate in vitro from their various parts, but a critical evaluation of such reports reveals that only a few complete medicinal plants have been regenerated and still fewer have actually been grown in soil, while their micropropagation on a mass scale has rarely been achieved, particularly in those medicinal plants where conventional propagation is inadequate, like, the mass clonal propagation of Dioscorea floribunda leading to its successful field trials. Such facts make it imperative to document the factual position of micropropagation of medicinal plants bringing out the advancements made along with the short falls, in this important area. The present review deals with the futuristic view on the said subject restricted to higher plants. PMID:18072537

  4. Gamma amino butyric acid accumulation in medicinal plants without stress

    Directory of Open Access Journals (Sweden)

    P Anju

    2014-01-01

    Results and Conclusion: Among the screened medicinal plants, Zingiber officinale and Solanum torvum were found to have GABA. The percentage of GABA present in Z. officinale and S. torvum were found to be 0.0114% and 0.0119%, respectively. The present work confirmed that among the selected CNS active medicinal plants, only two plants contain GABA. We found a negative correlation with plant having CNS activity and accumulation of GABA. The GABA shunt is a conserved pathway in eukaryotes and prokaryotes but, although the role of GABA as a neurotransmitter in mammals is clearly established, its role in plants is still vague.

  5. Turkish folk medicinal plants, VIII: Lalapa?a (Edirne

    Directory of Open Access Journals (Sweden)

    Ertan Tuzlac?

    2010-01-01

    Full Text Available In this study, the folk medicinal plants of Lalapa?a (Edirne were researched. During the field works, the information were obtained from local healers, experienced adults and patients by personal interviews and the specimens of the plants were collected. According to the results of the identifications of the specimens, 55 plant taxa are used in therapy in Lalapa?a. These are presented in a table in the text. Among them 44 taxa are wild and 11 taxa are cultivated plants. The folk medicinal plants are mostly used for stomach ailments, hemorrhoids, diabetes, cold and warts.

  6. The Protective Role of Anise Oil in Oxidative Stress and Genotoxicity Produced in Favism.

    Science.gov (United States)

    Koriem, Khaled M M; Arbid, Mahmoud S; El-Gendy, Nadia F

    2016-09-01

    The metabolic disease favism is an acute hemolytic anemia. Anise oil was obtained from Pimpinella anisum L. seeds (family Apiaceae). The objective of this study was to establish the protective effect of anise oil in favism disorders. Forty-eight male albino rats were divided into six groups: group 1 orally administrated 1 mL distilled water, group 2 orally received 300 mg/kg anise oil, and group 3 orally administrated 100 mg/kg anethole over a seven-day period, group 4 favism-induced rats, group 5 orally administrated 300 mg/kg anise oil and group 6 orally administrated 100 mg/kg anethole once a day over a seven-day period prior to favism induction. The result obtained revealed that oral administration of either anise oil or anethole into normal rats over a seven-day period did not induce any change. Following favism induction, hemoglobin, hematocrit, red and white blood cell counts, serum glucose, blood glutathione, glucose-6-phosphate dehydrogenase, total protein, globulin, alanine and aspartate aminotransferases levels were significantly decreased, while serum alkaline phosphatase and bilirubin showed significant increase. Pretreatment with either anise oil or anethole into favism-induced rats prevented these changes. Favism also induced deoxyribonucleic acid (DNA) damage and prior treatment of anise oil maintained liver DNA content. These results were supported by histopathological evaluation. In conclusion, anise oil pretreatment into favism-induced rats decreased the favism disorders, and this effect was related to the anethole ingredient of the oil. PMID:26745557

  7. Effects of medicinal plant extracts on gluconeogenesis

    Directory of Open Access Journals (Sweden)

    Andrade-Cetto A

    2012-06-01

    Full Text Available Adolfo Andrade-CettoLaboratorio de Etnofarmacología, Departamento de Biología Celular, Facultad de Ciencias, Universidad Nacional Autónoma de México, Coyoacán, MéxicoAbstract: On a global level, type 2 diabetes mellitus (T2DM is the most common endocrine disorder. T2DM is defined as an elevated blood glucose level associated with the absence of or inadequacy in pancreatic insulin secretion. The liver plays a key role in maintaining blood glucose levels during fasting by synthesizing glucose, mainly from lactate and amino acids through a process called gluconeogenesis. Because hepatic glucose production is increased at least twofold in patients with T2DM, targeting this pathway may lead to a blood glucose reduction in these patients. Botanical agents show promise for the development of new compounds to treat T2DM. Important mechanisms of action function via the inhibition of gluconeogenesis can occur in one of five ways: direct enzyme inhibition; through the downregulation of mRNA levels of fructose-1,6-bisphosphatase and glucose-6-phosphatase (G-6-P; through the activation of AMP-activated protein kinase, which leads to decreased levels of cAMP response element-binding protein, a key transcription factor for gluconeogenic enzyme phosphorylation; through the expression of the glucokinase gene, which stimulates glucokinase activity and inhibits G-6-P; and through the inhibition of phosphoenolpyruvate carboxykinase, which decreases gluconeogenesis and enzymatically inhibits G-6-P and fructose-1,6-diphosphatase.Keywords: type 2 diabetes mellitus, medicinal plants, gluconeogenesis, glucose 6-phosphatase, hepatic glucose production, endocrine disorder, fructose 1,6-diphosphatase

  8. Screening and antibacterial activity analysis of some important medicinal plants

    OpenAIRE

    G. Senthilmurugan Viji; B. Vasanthe; Kuru Suresh

    2013-01-01

    The screening and study of five different plant specimens belonging to different families for phytochemical constituents was performed using generally accepted laboratory technique for qualitative determinations. The constituents screened were saponins, combined anthraquinones, terpenoids, flavonoids, carotenoids, steroids, xantho proteins, couramins, alkaloids, quinones, vitamin C. The distribution of these constituents in the plant specimens were assessed and compared. The medicinal plant s...

  9. Essential oil and composition of anise (pimpinella anisum l.) with varying seed rates and row spacing

    International Nuclear Information System (INIS)

    Two year study was carried out to explore the effect of seed rate and row spacing on the fruit yield, essential oil yield and composition of aniseed. The study factors included seed rate (6 g, 12 g, 24 g/10 m2) and row spacing (15 cm, 25 cm, 37.5 cm. A significantly higher fruit yield was produced at narrow row spacing of 15 cm among treatments. Wider row spacing produced markedly higher essential oil than narrow row spacing. Essential oil accumulation decreased as planting densities increased. The major constituent of anise oil was trans-anethole (82.1%) followed by himachalene (7.0%). The quality parameters including estragol, himachalene and trans-anethole were significantly affected by different row spacing. Plant grown at 37.5 cm row spacing accumulated the highest estragol and trans-anethole concentration among the row spacing treatments. It can be concluded that higher plant density and wider row spacing increased the disease infestation and lodging cultivar Enza Zaden in current study exhibited high concentration trans-anethole in essential oil composition therefore is a good quality chemotype. (author)

  10. Traditional home gardens: A preserve of medicinal plants

    Directory of Open Access Journals (Sweden)

    Sangeeta Bajpai

    2013-06-01

    Full Text Available Traditional home gardens have been described as man-managed ecosystems with high energy subsidy, complex structure, and multiple functions. These have been reported as treasure trove of a rich biodiversity of plant species including medicinal plants used for traditional home remedies of various ailments. A review of research work on the status of medicinal plants in traditional rural home gardens is presented with the objective to explore them as potential preservation site for medicinal plants. From the available literature it can be ascertained that these traditional rural home gardens can be a suitable site for conservation, propagation, and expansion of medicinal plants that form the backbone of the traditional medicine system and are fast dwindling due to over exploitation and development pattern. Widely reported presence in rural home gardens of medicinal plant species, such as, Adhatoda vasica, Nees., Aloe vera, Mill., Asparagus racemosus, Willd., Chlorophytum tuberosum, Baker., Curcuma angustifolia, Roxb., Dioscorea bulbifera, L., Dioscorea hispida, Dennst., Emblica officinalis, Gaertn., Gymnema sylvestre, Br., Rauwolfia serpentina, Benth., Terminalia arjuna, (Roxb. Wight. and Arn., Tinospora cordifolia, Miers., that are considered endangered is a further confirmation of this belief that traditional rural home gardens can be a good conservation site for domestication and conservation of these plant species.

  11. Observations on plant usage in Xhosa and Zulu medicine

    Directory of Open Access Journals (Sweden)

    A. Hutchings

    1989-12-01

    Full Text Available The holistic concept of Xhosa and Zulu traditional medicine and some differences from Western orthodox practice are briefly outlined. The transmission of herbal knowledge within various social groups is outlined. The background, training and some procedures followed by five of the informants are discussed. Plant characteristics that may be seen, felt, smelled or tasted are considered as possible determinants of usage. The form of plant parts accounts for some usage in the more magically orientated medicines whereas colour, texture or the production of froth may signal the presence of medicinally active components such as tannin, mucilage and saponin. The role of plants producing a milky latex is discussed. Vesicant or irritant properties are utilized in septic or inflammatory conditions. Aromatic plants are used for respiratory or digestive disorders and pungent-smelling plants are used in the treatment of catarrh and some stress-related disorders. Bitter or sour- tasting plants may be used as an aid to digestion or serve a deterrent function. Parallel usage of some related plants in African and European herbal practice indicates that appropriate usage may be widely determined by easily discerned plant characteristics. Two herbal medicinal recipes recorded by the author and a list of medicinal plants collected in Transkei are presented.

  12. Screening of Burkholderia sp. WGB31 producing anisic acid from anethole and optimization of fermentation conditions.

    Science.gov (United States)

    Shen, Peihong; Song, Zhangyang; Zhang, Zhenyong; Zeng, Huahe; Tang, Xianlai; Jiang, Chengjian; Li, Junfang; Wu, Bo

    2014-11-01

    Anisic acid, the precursor of a variety of food flavors and industrial raw materials, can be bioconversed from anethole which extracted from star anise fruits. WGB31 strain with anisic acid molar production rate of 10.25% was isolated and identified as Burkholderia sp. Three significant influential factors, namely, glucose concentration, initial pH value, and medium volume were selected and their effects were evaluated by Box-Behnken Design (BBD). Regression analysis was performed to determine response surface methodology and the significance was tested to obtain the process model of optimal conditions for producing anisic acid. The fermentation conditions at the stable point of the model were obtained: glucose 6?g?L(-1) , pH 6.2, culture medium volume 61?mL in a triangular flask with 250?ml volume. Verification test indicated that the production rate of anisic acid was 30.7%, which was three times of that before optimizing. The results provide a basis and reference for producing anisic acid by microbial transformation. PMID:25100156

  13. IN VITRO ANTIMICROBIAL SCREENING OF SELECTED INDIAN MEDICINAL PLANTS

    OpenAIRE

    Varahalarao Vadlapudi; K Chandrashekar Naidu

    2010-01-01

    We have examined antimicrobial activities of medicinal plants Abultilon indicum, Adenocalymma alliaceum, Carica papaya, Crotolaria laburnifilia, Croton bonplandianum, Derris scandens, Eichornia crassipes, Iopomea hispida, Moringa heterohylla, Peltophorum pterocarpum that have been popularly used as folk medicines. Scientific information on antimicrobial properties of various natural sources is still rather scarce. The antimicrobial activities of the organic solvent extracts on the various tes...

  14. NEW DIMENSION OF MEDICINAL PLANTS AS ANIMAL FEED

    Directory of Open Access Journals (Sweden)

    M. A. TIPU, M. S. AKHTAR, M. I. ANJUM1 AND M. L. RAJA

    2006-07-01

    Full Text Available The medicinal plants and herbs have been used for many years in the treatment of various diseases in animals and human beings. Now-a-days, utilization of these medicinal plants is increasing. These are used in animal feed as the growth promoters. Due to prohibition of most of the antimicrobial growth promoters in animal feed because of their residual effects, plant extracts are becoming more popular. They act as antibacterial, antioxidant, anticarcinogenic, antifungal, analgesic, insecticidal, anticoccidial and growth promoters. These plant extracts compete with the synthetic drugs. Majority of medicinal plants do not have the residual effects. Azadiracht indica, Zizyphus vulgaris, Ocimum gratissimum and Atlanta monophylla have the strong antibacterial activity, whereas ocimum plant has strong antioxidant, anticarcinogenic, antifungal, analgesic and antipyretic properties. Leaves of Azadirachta indica are used for feeding and reducing the parasitic load of animals. The fruit of Azadirachta indica also has the anticoccidial activity for poultry.

  15. Plants used in traditional medicine of China and Brazil

    OpenAIRE

    F.J.A. Matos; M. I. L. Machado; J. W. Alencar; M. E. O. Matos; A. A. Craveiro

    1991-01-01

    Eventhough the rationale behind the use of medicinal plantes in Brazil and Chine is different, twenty four species are used in both countries. Scientific name, vulgar name and uses in both countries along with their chemical constituents are listed.

  16. MEDICINAL PLANTS WITH POTENTIAL ANTICANCER ACTIVITIES: A REVIEW

    Directory of Open Access Journals (Sweden)

    Narah Merina

    2012-06-01

    Full Text Available Plants have been the beacon of therapeutic sources for curing diseases from times immemorial. Medicinal plants with their isolated lead molecules are also used as an alternative medicine for treating neoplastic cells. Neoplastic cells are the anomalous proliferation of cells in the body which cause cancer. Diverse efficient compounds derived from natural products have been isolated as anticancer agents. These chemical compounds are formulated with a view to create effective drugs against cancer. Some of the lead molecules isolated from different medicinal plants are already in use to treat cancer and chemotherapeutic side effects. These potential and successful anticancer molecules include Vincristine, Vinblastin, Taxol, Camptothecin and Podophyllotoxin. This paper deals with the selective medicinal plants having anticancer properties which could be further designed to produce cancer curing drugs.

  17. Multimedia-based Medicinal Plants Sustainability Management System

    Directory of Open Access Journals (Sweden)

    Zacchaeus Omogbadegun

    2011-09-01

    Full Text Available Medicinal plants are increasingly recognized worldwide as an alternative source of efficacious and inexpensive medications to synthetic chemo-therapeutic compound. Rapid declining wild stocks of medicinal plants accompanied by adulteration and species substitutions reduce their efficacy, quality and safety. Consequently, the low accessibility to and non-affordability of orthodox medicine costs by rural dwellers to be healthy and economically productive further threaten their life expectancy. Finding comprehensive information on medicinal plants of conservation concern at a global level has been difficult. This has created a gap between computing technologies' promises and expectations in the healing process under complementary and alternative medicine. This paper presents the design and implementation of a Multimedia-based Medicinal Plants Sustainability Management System addressing these concerns. Medicinal plants' details for designing the system were collected through semi-structured interviews and databases. Unified Modelling Language, Microsoft-Visual-Studio.Net, C#3.0, Microsoft-Jet-Engine4.0, MySQL, Loquendo Multilingual Text-to-Speech Software, YouTube, and VLC Media Player were used.

  18. Conception of an antimalaria medicinal product from plants used in traditional medicine

    OpenAIRE

    Balansard, Guy

    2014-01-01

    AbstractThe methodology adopted aims at validating remedies used in traditional medicine and enhancing plants open for development.The process is three-staged:- Ethnobotanical surveys, first with a general scope and then targeting the plant selected;- Phytochemical, pharmacological and toxicological studies;- Development of a drug, following the procedure to obtain permission to market a herbal medicinal product (cf. Cahier published by Agence Française no. 3) including a pharmaceutical dossi...

  19. An empirical investigation on factors influencing on exporting medicinal plants

    OpenAIRE

    Hoda Nosouzi; Naser Azad; Abdollah Naami

    2013-01-01

    During the past few years, there have been growing interests on developing medicinal plant industry. This paper presents an empirical study on important factors influencing medicinal plant for developing exports in Iran. The proposed study of this paper designs a questionnaire and distributes it among 310 regular customers who are involved in this industry in city of Tehran, Iran. Cronbach alpha has been calculated as 0.802. In addition, Kaiser-Meyer-Olkin Measure of Samplng =KMO test was als...

  20. Historical versus contemporary medicinal plant uses in Ghana

    DEFF Research Database (Denmark)

    Soelberg, Jens; Asase, A; Akwetey, G; Jäger, A K

    2015-01-01

    ETHNOPHARMACOLOGICAL RELEVANCE: Three extraordinary, historical documents stemming from observations made in 1697, 1803 and 1817 quote medicinal plant uses among the Fante, Ga and Ashanti people of present-day Ghana, and can be linked to original botanical specimens in European herbaria. This provides a unique opportunity to gain insight to the historical materia medica of Ghana and compare this to contemporary medicinal plant uses. By critical literary and taxonomic review, the present study (r...

  1. Quantification of Gallic Acidin Fruits of Three Medicinal Plants

    OpenAIRE

    Vazirian, Mahdi; KHANAVI, Mahnaz; Amanzadeh, Yaghoub; Hajimehdipoor, Homa

    2011-01-01

    Triphala is a traditional herbal formulation consisting of dried fruits originating from three medicinal plants, namely Terminalia chebula, Terminalia bellerica and Phyllanthus emblica. It is used in folk medicine for the treatment of headaches, dyspepsia and leucorrhoea. There are some reports regarding Triphala’s pharmacological effects including its anti-cancer, radioprotective, hypocholesterolaemic, hepatoprotective and anti-oxidant activities. The most important components of these plant...

  2. ANTIVIRAL POTENTIAL OF MEDICINAL PLANTS: AN OVERVIEW

    OpenAIRE

    Ruwali Pushpa; Rai Nishant; Kumar Navin; Gautam Pankaj

    2013-01-01

    The term ‘Antiviral agents’ has been defined in very broad terms as substances other than a virus or virus containing vaccine or specific antibody which can produce either a protective or therapeutic effect to the clear detectable advantage of the virus infected host. The herbal medicine has a long traditional use and the major advantage over other medicines is their wide therapeutic window with rare side effects. There are some disadvantages of synthetic drugs like narrow therapeutic window...

  3. Turkish folk medicinal plants, VIII: Lalapa?a (Edirne)

    OpenAIRE

    Ertan Tuzlac?; Duygu Fatma Alparslan ??bilen; Gizem Bulut

    2014-01-01

    ABSTRACT: In this study, the folk medicinal plants of Lalapa?a (Edirne) were researched.During the field works, the information were obtained from local healers, experienced adultsand patients by personal interviews and the specimens of the plants were collected. Accordingto the results of the identifications of the specimens, 55 plant taxa are used in therapy inLalapa?a. These are presented in a table in the text. Among them 44 taxa are wild and 11 taxaare cultivated plants. The folk medicin...

  4. MEDICINAL PLANTS OF RAJASTHAN (INDIA WITH ANTIDIABETIC POTENTIAL

    Directory of Open Access Journals (Sweden)

    Batra Shikha

    2011-03-01

    Full Text Available Rajasthan has a rich heritage of traditional system of medicine and many medicinally useful plants are found growing wildly because of vast area and variety of agro-climatic conditions. These plants are being used for the treatment of many human ailments including diabetes. Plants that are specifically employed for the treatment of diabetes are Acacia nilotica, Acacia senegal, Aegle marmelos, Calotropis procera, Capparis deciduas, Cassia auriculata, Cassia sophera, Cayratia trifolia, Cyamopsis tetragonoloba, Dalbergia sisso, Gymnema sylvestre, Momordica charantia, Syzygium cumini, Withania somnifera. This article aims to provide a comprehensive review on the some plants of Rajasthan having antidiabetic potential.

  5. Traditional uses of medicinal plants of uzumlu district, erzincan, turkey

    International Nuclear Information System (INIS)

    A list of medicinal plants used by local people in uzumlu district and its villages is presented. This study included the first detailed ethnobotanical survey carried out in Erzincan. The study was conducted during spring and summer periods in 2010 and 2011 through face-to-face interview method to determine the local names, used parts, and medicinal usages of the determined plants. The plant samples collected from the study area were pressed, dried, and labeled according to the herbarium techniques, and identified. Totally 64 plant taxa belonging to 53 genera and 29 families were used by local people for different medicinal purposes in the area. The families including the highest number of taxa were Rosaceae (11 species), Asteraceae (6 species) and Lamiaceae (5 species). The species with the highest number of usage as herbal medicine were Urtica dioica, Anthemis cretica subsp. iberica, Petroselinum crispum,Allium cepa, Rheum ribes, Rosa dumalis subsp. boissieri var. boissieri and Vitis vinifera. Fruits and flowers were the most widely used parts of the plants. Decoction was the main method for using, and the primary therapeutic use of herbal remedies was for the respiratory system diseases such as cold, cough, asthma, and bronchitis.This study was the first carried out on 20 plant taxa used as traditional medicine, and the use of 28 taxa were recorded for the first time in Turkey. For maintaining the knowledge on traditional medicine, urgent studies should be carried out for recording before they have been completely lost. (author)

  6. Antioxidant Properties of Medicinal Plants from Peru

    OpenAIRE

    Iwona Wawer; Katarzyna Paradowska; Katarzyna Zawada; Adam Ber?owski

    2013-01-01

    There is a wide diversity of plants and seasonal crops in Peru, due to the presence of many climatic zones. Numerous plants are used to cure or prevent diseases. These plants are promising candidates for functional foods products. The most frequent form in which they are used is an aqueous infusion or decoction. In this study, we compared the antioxidant properties of ten Peruvian plants infusions and investigated their relation to the phenolic content. The studied plants were: Uncaria toment...

  7. Molecular markers in medicinal plant biotechnology: past and present.

    Science.gov (United States)

    Sarwat, Maryam; Nabi, Gowher; Das, Sandip; Srivastava, Prem Shankar

    2012-03-01

    Plant based medicines have gained popularity worldwide due to their almost negligible side effects. In India, the three traditional medicinal systems, namely homeopathy, Ayurveda and Siddha rely heavily on plants for medicinal formulations. To prevent the indiscriminate collection of these valuable medicinal plants and for their proper authentication and conservation, it is imperative to go for sustained efforts towards proper germplasm cataloguing and devising conservation strategies. For this purpose, molecular markers have a significant role, as they provide information ranging from diversity at nucleotide level (single nucleotide polymorphisms) to gene and allele frequencies (genotype information), the extent and distribution of genetic diversity, and population structure. Over the past twenty years, the molecular marker field has completely transformed the meaning of conservation genetics which has emerged from a theory-based field of population biology to a full-fledged pragmatic discipline. In this review, we have explored the transition and transformation of molecular marker technologies throughout these years. PMID:21649550

  8. Collection and conservation of medicinal and aromatic plants resources

    Directory of Open Access Journals (Sweden)

    Z. Abraham

    2011-01-01

    Full Text Available (Abstract selected from presentation in National Conference on Biodiversity of Medicinal and Aromatic Plants: Collection, Characterization and Utilization, held at Anand, India during November 24-25, 2010Plant genetic resources have made substantial contributions to the domestication, utilization and improvement of all kinds of crops including medicinal and aromatic plants. Collection, characterization and  their efficient utilization are keys to efficient management of any kind of genetic resource including those of medicinal and aromatic plants. Modern techniques offer the opportunity for collecting, rapid propagation, medium and long-term storage and distribution of germplasm. Complementary  strategies are significant for conservation, particularly of medicinal and aromatic plants as we come across a wide spectrum of species with orthodox or recalcitrant or intermediate seed storage behaviour or exclusively vegetatively propagated plants. Collections from different and widely placed areas will greatly enhance the existing collections in genebanks by providing back-ups in case of losses through diseases, insects and environmental stresses and weather changes. The major objectives of conservation programmes are to provide safety against loss of genetic resources and to make these resources available for crop improvement at present and in the future. Each strategy for conservation has to offer relatively greater safety and cost effectiveness. Any useful plant can be considered for conservation but medicinal plants with known biological activities and chemical constituents responsible for such activities if influenced by agro-ecological situations needs to be conserved in ideal situations to avoid loss of essential compounds responsible for biological actions. However, prioritisation of species is essential to make full use of any particular strategy with justification. Modification of the environment and particularly associations combined with any treatment exercised for survival or increasing productivity needs to be approached cautiously. This lecture will review the available information on collection, characterization, utilization, conservation and documentation of genetic resources belonging to medicinal and aromatic plants.  

  9. Antioxidant activity and protecting health effects of common medicinal plants.

    Science.gov (United States)

    Škrovánková, So?a; Mišurcová, Ladislava; Mach?, Ludmila

    2012-01-01

    Medicinal plants are traditionally used in folk medicine as natural healing remedies with therapeutic effects such as prevention of cardiovascular diseases, inflammation disorders, or reducing the risk of cancer. In addition, pharmacological industry utilizes medicinal plants due to the presence of active chemical substances as agents for drug synthesis. They are valuable also for food and cosmetic industry as additives, due to their preservative effects because of the presence of antioxidants and antimicrobial constituents. To commonly used medicinal plants with antioxidant activity known worldwide belong plants from several families, especially Lamiaceae (rosemary, sage, oregano, marjoram, basil, thyme, mints, balm), Apiaceae (cumin, fennel, caraway), and Zingiberaceae (turmeric, ginger). The antioxidant properties of medicinal plants depend on the plant, its variety, environmental conditions, climatic and seasonal variations, geographical regions of growth, degree of ripeness, growing practices, and many other factors such as postharvest treatment and processing. In addition, composition and concentration of present antioxidants, such as phenolic compounds, are related to antioxidant effect. For appropriate determination of antioxidant capacity, the extraction technique, its conditions, solvent used, and particular assay methodology are important. PMID:23034115

  10. Ontology Mapping of Indian Medicinal Plants with Standardized Medical Terms

    Directory of Open Access Journals (Sweden)

    S. Waheeta Hopper

    2012-01-01

    Full Text Available Problem statement: World Wide Web (WWW consisting large volume of information related with medicinal plants. However health care recommendation with Indian Medicinal Plants becomes complicated because valuable Information about medicinal resources as plants is scattered, in text form and unstructured. Search engines are not quite efficient and require excessive manual processing. Therefore search becomes difficult for the ordinary users to find the medicinal uses of herbal plants from the web. And another problem is that the domain experts could not able to map the medicinal uses of herbal plants with the existing standardized medical terms. Mapping the existing ontology introduces the problem of finding the similarity between the terms and relationships. Finding the solution to perform automatic mapping is another major challenge to be solved. Approach: To address these issues we developed a Knowledge framework for the Indian Medicinal Plants (KIMP. Knowledge framework includes the ontology creation, user interface for querying the system. Jena is used to build semantic web applications with the ontology representation of Resource Description Framework (RDF and Web Ontology Language (OWL. SPARQL Protocol and RDF Query Language (SPARQL is used to retrieve various query patterns. Automated mapping is achieved by considering lexical and edge based relatedness. Results: The user interface is demonstrated for five thousand concepts, which gives the related information from Wikipedia web page in three languages. Mapping recommendation by the lexical similarity Jaccard algorithm gives 27% and Jaro Winkler algorithm gives 60%. Edge based relationship using WuPalmer algorithm gives 93% mapping recommendation. These are analyzed and compared with our algorithm based on WuPalmer gives more specific mapping results than WuPalmer with 71%. Conclusion: Thus it possible to find the specific resultant web page based on the user requirement in three different languages. The mapping with standardized ontology gives more improvement in analyzing the performance of the medicinal plants and their uses.

  11. Plantas medicinais: cura segura? / Medicinal plants: safe cure?

    Scientific Electronic Library Online (English)

    Valdir F., Veiga Junior; Angelo C., Pinto; Maria Aparecida M., Maciel.

    2005-06-01

    Full Text Available [...] Abstract in english This paper reviews the recent literature on synergism, adulteration and risks of using medicinal plants. The use of copaiba and sacaca plants as well as their adulteration and side effects, are also described. In addition, the new regulations on phytotherapeutic registration in Brazil and Europe are [...] discussed.

  12. Plantas medicinais: cura segura? Medicinal plants: safe cure?

    OpenAIRE

    Valdir F Veiga Junior; Angelo C. Pinto; Maria Aparecida M. Maciel

    2005-01-01

    This paper reviews the recent literature on synergism, adulteration and risks of using medicinal plants. The use of copaiba and sacaca plants as well as their adulteration and side effects, are also described. In addition, the new regulations on phytotherapeutic registration in Brazil and Europe are discussed.

  13. POLYPHENOLS AND FLAVONOIDS OF TWELVE INDIAN MEDICINAL PLANTS

    OpenAIRE

    Dishant Desai; Dilip Bhayani; Sumitra Chandra

    2013-01-01

    In the present work, twelve Indian medicinal plants (Averrhoa carambola L., Buchanania lanzan Spr., Calophylluminophyllum L., Celastrus paniculatus Willd., Clerodendron multiflorum L., Luffa acutangula (L.) Roxb., Morindacitrifolia L., Ocimum gratissimum L., Peltophorum ferrugineum (Decne.), Phyllanthus fraternus Webster Syn.,Triumfetta rotundifolia Lam. and Ziziphus nummularia (Burm. F.) were evaluated for their total phenol andflavonoid content. The plant material was extracted individually...

  14. Pharmacological effects of medicinal plants on skin

    Directory of Open Access Journals (Sweden)

    Zohreh Bakhtiyari, MSc

    2013-06-01

    There are many herbs that have a role in the prevention and treatment of skin diseases, and are used in either traditional medicine or the preparation of cosmetics. The effects of a number of them have been scientifically proved and this information for the production of cosmetic and pharmaceutical products can be used.

  15. Medicinal plants in an urban environment: the medicinal flora of Banares Hindu University, Varanasi, Uttar Pradesh

    Directory of Open Access Journals (Sweden)

    Bussmann Rainer W

    2007-11-01

    Full Text Available Abstract Varanasi is one of the oldest continuously inhabited cities of the world, and one of the most important Hindu pilgrimage sites. Despite this importance, very little information exits on the cities flora in general, and medicinal species found within its limit in particular. Traditional medicine plays a large role in Indian society. The presented study attempted to investigate if traditional plant use and availability of important common medicinal plants are maintained in urban environments. The paper presents information on the traditional uses of seventy-two plant species collected form the campus of Banares Hindu University, Varanasi, Uttar Pradesh, and highlights the uses of these plants by the local inhabitants.

  16. Plant Secondary Metabolites in some Medicinal Plants of Mongolia Used for Enhancing Animal Health and Production

    OpenAIRE

    Makkar, HPS.; Norvsambuu, T.; Lkhagvatseren, S.; Becker, K

    2009-01-01

    The levels and activities of a number of plant secondary metabolites (PSMs) are known to increase in response to increase in stress. The Mongolian plants considered to possess medicinal properties may contain novel compounds since they are exposed to severe conditions; such plants could become good candidates for modern drug discovery programmes. Information on distribution, palatability to livestock and opinion of local people on their nutritive and medicinal values was compiled for 15 plant...

  17. Berberis lycium a Medicinal Plant with Immense Value

    Directory of Open Access Journals (Sweden)

    Monika Sood2

    2013-03-01

    Full Text Available Berberis lycium belong to family Berberidaceae is an evergreen shrub growing in Himalayan region. The various parts of the plant like root, bark, stem, leaves and fruits are used by the people as a medicine or food. This plant has also gained wide acceptance for its medicinal value in ayurvedic drugs. The plant is known to prevent liver disorders, abdominal disorders, skin diseases, cough, ophthalmic etc. Moreover the pharmacological studies have shown that plant is hypoglycemic, hyperlipidemic, hepatoprotective, anticarcinogenic and antipyretic properties. The fruits of the plant are also very nutritious and are rich source of vitamins, minerals, antioxidants, anthocyanin etc. These fruits are consumed in raw form or are utilized in the preparation of juices, jams, preserve etc. by the local inhabitants. In the present article an attempt has been made to summarize the various properties of Berberis lycium plant.

  18. Anti-HIV activity of Indian medicinal plants.

    Science.gov (United States)

    Sabde, Sudeep; Bodiwala, Hardik S; Karmase, Aniket; Deshpande, Preeti J; Kaur, Amandeep; Ahmed, Nafees; Chauthe, Siddheshwar K; Brahmbhatt, Keyur G; Phadke, Rasika U; Mitra, Debashis; Bhutani, Kamlesh Kumar; Singh, Inder Pal

    2011-07-01

    Acquired immunodeficiency syndrome patients face great socio-economic difficulties in obtaining treatment. There is an urgent need for new, safe, and cheap anti-HIV agents. Traditional medicinal plants are a valuable source of novel anti-HIV agents and may offer alternatives to expensive medicines in future. Various medicinal plants or plant-derived natural products have shown strong anti-HIV activity and are under various stages of clinical development in different parts of the world. The present study was directed towards assessment of anti-HIV activity of various extracts prepared from Indian medicinal plants. The plants were chosen on the basis of similarity of chemical constituents with reported anti-HIV compounds or on the basis of their traditional usage as immunomodulators. Different extracts were prepared by Soxhlet extraction and liquid-liquid partitioning. Ninety-two extracts were prepared from 23 plants. Anti-HIV activity was measured in a human CD4+ T-cell line, CEM-GFP cells infected with HIV-1NL4.3. Nine extracts of 8 different plants significantly reduced viral production in CEM-GFP cells infected with HIV-1NL4.3. Aegle marmelos, Argemone mexicana, Asparagus racemosus, Coleus forskohlii, and Rubia cordifolia demonstrated promising anti-HIV potential and were investigated for their active principles. PMID:21365365

  19. The microbiome of medicinal plants: diversity and importance for plant growth, quality and health

    OpenAIRE

    MartinaKöberl; ElshahatM.Ramadan; RudolfBauer

    2013-01-01

    Past medicinal plant research primarily focused on bioactive phytochemicals, however, the focus is currently shifting due to the recognition that a significant number of phytotherapeutic compounds are actually produced by associated microbes or through interaction with their host. Medicinal plants provide an enormous bioresource of potential use in modern medicine and agriculture, yet their microbiome is largely unknown. The objective of this review is (i) to introduce novel insights into the...

  20. Medicinal plants in Mexico: healers' consensus and cultural importance.

    Science.gov (United States)

    Heinrich, M; Ankli, A; Frei, B; Weimann, C; Sticher, O

    1998-12-01

    Medicinal plants are an important element of indigenous medical systems in Mexico. These resources are usually regarded as part of a culture's traditional knowledge. This study examines the use of medicinal plants in four indigenous groups of Mexican Indians, Maya, Nahua, Zapotec and - for comparative purposes - Mixe. With the first three the methodology was similar, making a direct comparison of the results possible. In these studies, the relative importance of a medicinal plant within a culture is documented using a quantitative method. For the analysis the uses were grouped into 9-10 categories of indigenous uses. This report compares these data and uses the concept of informant consensus originally developed by Trotter and Logan for analysis. This indicates how homogenous the ethnobotanical information is. Generally the factor is high for gastrointestinal illnesses and for culture bound syndromes. While the species used by the 3 indigenous groups vary, the data indicate that there exist well-defined criteria specific for each culture which lead to the selection of a plant as a medicine. A large number of species are used for gastrointestinal illnesses by two or more of the indigenous groups. At least in this case, the multiple transfer of species and their uses within Mexico seems to be an important reason for the widespread use of a species. Medicinal plants in other categories (e.g. skin diseases) are usually known only in one culture and seem to be part of its traditional knowledge. PMID:9877354

  1. The cultivation of of medicinal and aromatique plants in Romania

    Directory of Open Access Journals (Sweden)

    Leon Sorin MUNTEAN

    1985-08-01

    Full Text Available Scientific research regarding medicinal plants started first in Cluj, where the Research Station for Medicinal Plants was first organized in Europe (1904. Research in this field was continued after 1930 by the staff of the Agronomy Researh Institute of Romania (ICAR. Beginning with 1975 the national research programme regarding the medicinal plants is coordinated by the Research Station for Medicinal and Aromatic Plants -SCPMA - Fundulea. Studies are performed in the experimental fields and in the laboratories of this institute and different other research stations and universities in Romania. Beginning with 1979, a new specialized periodical - Herba Romanica - published the main results in the field. At present there are cultivated in Romania about 60 different medicinal and aromatic plant species. Recently a tendency emerged toward the concentration of the production to the most suitable regions and the specialization of different farms for the cultivation of a more restricted number of species. In the second part of the paper the species studied and/or cultivated in the experimental fields of the Agronomy Institute Cluj-Napoca are presented with a chronological list of papers published by the stuff in the period 1975-1984.

  2. Genomics and Evolution in Traditional Medicinal Plants: Road to a Healthier Life

    OpenAIRE

    Da-Cheng Hao; Pei-Gen Xiao

    2015-01-01

    Medicinal plants have long been utilized in traditional medicine and ethnomedicine worldwide. This review presents a glimpse of the current status of and future trends in medicinal plant genomics, evolution, and phylogeny. These dynamic fields are at the intersection of phytochemistry and plant biology and are concerned with the evolution mechanisms and systematics of medicinal plant genomes, origin and evolution of the plant genotype and metabolic phenotype, interaction between medicinal pla...

  3. Antiamoebic and phytochemical screening of some Congolese medicinal plants.

    Science.gov (United States)

    Tona, L; Kambu, K; Ngimbi, N; Cimanga, K; Vlietinck, A J

    1998-05-01

    Results from the in vitro antiamoebic activity of some Congolese plant extracts used as antidiarrhoeic in traditional medicine indicated that of 45 plant extracts tested, 35 (77.78%) exhibited an antiamoebic activity and 10 (22.22%) were inactive. The highest activity (MIC Tithonia diversifolia. Metronidazole used as reference product showed a more pronounced activity than that of all plant extracts tested. PMID:9687082

  4. Rice-Traditional Medicinal Plant in India

    OpenAIRE

    M.Umadevi; Pushpa, R; K.P. Sampathkumar; Debjit Bhowmik

    2012-01-01

    Rice is rich in genetic diversity, with thousands of varieties grown throughout the world. Rice cultivation is the principal activity and source of income for about 100 million households in Asia and Africa. Rice has potential in a wide range of food categories. Besides having nutritional and medicinal benefits, the by-products of rice are equally important and beneficial. By-products from growing rice create many valuable and worthwhile products. The unedible parts, that are discarded throug...

  5. Analysis of vitamin C in selected medicinal plants

    International Nuclear Information System (INIS)

    Vitamin C or ascorbic acid, a very useful constituent of redox mechanism is used in medicine and also added in manufactured food for anti-oxidation. A UV-spectrophotometric method was used for the determination of Vitamin C in 4 different medicinal plants. High amount of Vitamin C 160 mg/100 g was found in Citrulus colcocynthis, followed by Hippophae rhamonides oil 136.1 mg/100g. A relatively low concentration of Vitamin C was recorded in Glycyrhiza glabra 56.2 mg/100g and Withinia somnifera 51.50 mg/100 g. The presence of high concentration of Vitamin C in selected medicinal plants might be responsible for their therapeutic effects and uses in the traditional system of medicine. (author)

  6. Synthesis, crystal structure and properties of magnesium and calcium salts of p-anisic acid

    Indian Academy of Sciences (India)

    Kiran T Dhavskar; Pooja H Bhargao; Bikshandarkoil R Srinivasan

    2016-03-01

    The synthesis, crystal structure and properties of the magnesium and calcium salts of p-anisic acid viz. [Mg(H2O)6](C8H7O3)2·2H2O (C8H7O3=p-anisate or 4-methoxybenzoate) (1) and [Ca(H2O)(C8H7O3)2] (2) are reported. The p-anisate ion is not coordinated to Mg(II) and functions as a charge balancing counter anion for the centrosymmetric octahedral [Mg(H2O)6]2+ unit in 1. The unique lattice water molecule links pairs of [Mg(H2O)6] 2+ cations and p-anisate anions with the aid of O-H···O interactions. The μ2-bridging bidentate and the μ3-bridging tetradentate binding modes of the crystallographically unique p-anisate ligands in (2) result in a two-dimensional (2-D) coordination polymer.

  7. People, plants and health: a conceptual framework for assessing changes in medicinal plant consumption

    Directory of Open Access Journals (Sweden)

    Smith-Hall Carsten

    2012-11-01

    Full Text Available Abstract Background A large number of people in both developing and developed countries rely on medicinal plant products to maintain their health or treat illnesses. Available evidence suggests that medicinal plant consumption will remain stable or increase in the short to medium term. Knowledge on what factors determine medicinal plant consumption is, however, scattered across many disciplines, impeding, for example, systematic consideration of plant-based traditional medicine in national health care systems. The aim of the paper is to develop a conceptual framework for understanding medicinal plant consumption dynamics. Consumption is employed in the economic sense: use of medicinal plants by consumers or in the production of other goods. Methods PubMed and Web of Knowledge (formerly Web of Science were searched using a set of medicinal plant key terms (folk/peasant/rural/traditional/ethno/indigenous/CAM/herbal/botanical/phytotherapy; each search terms was combined with terms related to medicinal plant consumption dynamics (medicinal plants/health care/preference/trade/treatment seeking behavior/domestication/sustainability/conservation/urban/migration/climate change/policy/production systems. To eliminate studies not directly focused on medicinal plant consumption, searches were limited by a number of terms (chemistry/clinical/in vitro/antibacterial/dose/molecular/trial/efficacy/antimicrobial/alkaloid/bioactive/inhibit/antibody/purification/antioxidant/DNA/rat/aqueous. A total of 1940 references were identified; manual screening for relevance reduced this to 645 relevant documents. As the conceptual framework emerged inductively, additional targeted literature searches were undertaken on specific factors and link, bringing the final number of references to 737. Results The paper first defines the four main groups of medicinal plant users (1. Hunter-gatherers, 2. Farmers and pastoralists, 3. Urban and peri-urban people, 4. Entrepreneurs and the three main types of benefits (consumer, producer, society-wide derived from medicinal plants usage. Then a single unified conceptual framework for understanding the factors influencing medicinal plant consumption in the economic sense is proposed; the framework distinguishes four spatial levels of analysis (international, national, local, household and identifies and describes 15 factors and their relationships. Conclusions The framework provides a basis for increasing our conceptual understanding of medicinal plant consumption dynamics, allows a positioning of existing studies, and can serve to guide future research in the area. This would inform the formation of future health and natural resource management policies.

  8. A pharmacological appraisal of medicinal plants with antidiabetic potential

    OpenAIRE

    Khan, Vasim; Najmi, Abul Kalam; Akhtar, Mohd.; Aqil, Mohd; Mujeeb, Mohd; K. K. Pillai

    2012-01-01

    Diabetes mellitus is a complicated metabolic disorder that has gravely troubled the human health and quality of life. Conventional agents are being used to control diabetes along with lifestyle management. However, they are not entirely effective and no one has ever been reported to have fully recovered from diabetes. Numerous medicinal plants have been used for the management of diabetes mellitus in various traditional systems of medicine worldwide as they are a great source of biological co...

  9. Rapid Identification and Verification of Indirubin-Containing Medicinal Plants

    OpenAIRE

    Hu, Zhigang; Tu, Yuan; Xia, Ye; Cheng, Peipei; Sun, Wei; Shi, Yuhua; Guo, Licheng; He, Haibo; Xiong, Chao; Chen, Shilin; Zhang, Xiuqiao

    2015-01-01

    Indirubin, one of the key components of medicinal plants including Isatis tinctoria, Polygonum tinctorium, and Strobilanthes cusia, possesses great medicinal efficacy in the treatment of chronic myelocytic leukemia (CML). Due to misidentification and similar name, materials containing indirubin and their close relatives frequently fall prey to adulteration. In this study, we selected an internal transcribed spacer 2 (ITS2) for distinguishing these indirubin-containing species from five of the...

  10. Cameroonian medicinal plants: Pharmacology and derived natural products

    Directory of Open Access Journals (Sweden)

    ThomasEfferth

    2010-10-01

    Full Text Available Many developing countries including Cameroon have mortality patterns that reflect high levels of infectious diseases and the risk of death during pregnancy and childbirth, in addition to cancers, cardiovascular diseases and chronic respiratory diseases that account for most deaths in the developed world. Several medicinal plants are used traditionally for their treatment. In this review, plants used in Cameroonian traditional medicine with evidence for the activities of their crude extracts and/or derived products have been discussed. A considerable number of plant extracts and isolated compounds possess significant antimicrobial, antiparasitic including anti-malarial, anti-proliferative, anti-inflammatory, anti-diabetes, and antioxidant effects. Most of the biologically active compounds belong to terpenoids, phenolics and alkaloids. Terpenoids from Cameroonian plants showed best activities as anti-parasitic, but rather poor antimicrobial effects. The best antimicrobial, anti-proliferative and antioxidant compounds were phenolics. In conclusion, many medicinal plants traditionally used in Cameroon to treat various ailments displayed good activities in vitro. This explains the endeavor of Cameroonian research institutes in drug discovery from indigenous medicinal plants. However, much work is still to be done to standardize methodologies and to study the mechanisms of action of isolated natural products.

  11. Analysis of the Mercury in commonly used Medicinal Plants

    Directory of Open Access Journals (Sweden)

    Meenakshi N

    2014-07-01

    Full Text Available Medicinal plants are used in various herbal products as food supplements and food additive. The requirement of medicinal plants is tremendously increasing in the global market. The presence of variousl heavy metals such as Arsenic, Mercury, Lead, Cadmium, Chromium, Nickle,silver, Atimony,Copper etc in herbal formulations result in several adverse effects. The present study was done to determine the presence of Mercury in some of the selected medicinal plants namely Hemidesmus indicus (L. R.Br. (Sariba, Cyperus rotundus L. (Musta, Glycyrrhiza glabra L. (Yashtimadhu, Rubia cordifolia L. (Manjishta, Eclipta alba Hassk (Bhringaraj, Hedychium spicatum Ham.ex Smith (Karchura, Emblica officinalis Gaertn. (Amalaki and Acacia concinna (Willd. DC. (Shikakai, which were procured from local market of Chennai, Tirupati and Hyderabad. The samples were digested by Wet digestion method and analysed by UV-Vis Spectrophotometer. The results were compared with permissible limits recommended by WHO. Mean levels were evaluated with respect to their procurement. It was found that the analyzed plant species contained safe levels of the heavy metals concentration excepting Sariba Tirupati sample, Yastimadhu Chennai sample and Manjishta Hyderabad sample. There was a considerable variation of heavy metal concentration for the examined medicinal plant species. This may be due to the difference in physiological properties of plant uptake.

  12. POTENTIAL OF MEDICINAL PLANTS IN KIDNEY, GALL AND URINARY STONES

    Directory of Open Access Journals (Sweden)

    Choubey Ankur

    2010-06-01

    Full Text Available Medicinal plants have been known for millennia and are highly esteemed all over the world as a rich source of therapeutic agents for the prevention of various ailments. Today large number of population suffers from kidney stone, gall stone and urinary calculi. Stone disease has gained increasing significance due to changes in living conditions i.e. industrialization and malnutrition. Changes in prevalence and incidence, the occurrence of stone types and stone location, and the manner of stone removal are explained. Medicinal plants are used from centuries due to its safety, efficacy, cultural acceptability and lesser side effects as compared to synthetic drugs. The present article deals with measures to be adopted for the potential of medicinal plants in stone dissolving activity.

  13. IN VITRO ANTIMICROBIAL SCREENING OF SELECTED INDIAN MEDICINAL PLANTS

    Directory of Open Access Journals (Sweden)

    Varahalarao Vadlapudi

    2010-10-01

    Full Text Available We have examined antimicrobial activities of medicinal plants Abultilon indicum, Adenocalymma alliaceum, Carica papaya, Crotolaria laburnifilia, Croton bonplandianum, Derris scandens, Eichornia crassipes, Iopomea hispida, Moringa heterohylla, Peltophorum pterocarpum that have been popularly used as folk medicines. Scientific information on antimicrobial properties of various natural sources is still rather scarce. The antimicrobial activities of the organic solvent extracts on the various test microorganisms, including bacteria and fungi investigated using agar well diffusion technique. The length of inhibition zone was measured in millimeters from the edge of the well to the edge of the inhibition zone. Methanol extracts exhibited promising antimicrobial activity than chloroform and hexane extracts. The extracts from varies parts of plants were assessed in an effort to validate the medicinal potential of the herb. Our results showed plant extracts have significant levels of antimicrobial activity.

  14. Antibacterial activity of plants used in Indian herbal medicine

    Directory of Open Access Journals (Sweden)

    Pavithra P

    2010-01-01

    Full Text Available Delonix elata , Enicostemma axillare, Merremia tridentata, Mollugo cerviana and Solanum incanum are medicinal plants used in traditional Indian medicine for the treatment of various ailments. These plants were selected to evaluate their potential antibacterial activity. To determine antibacterial activity and phytochemicals in the crude extracts of five medicinal plants used in traditional Indian medicine for the treatment of various ailments like rheumatism, piles fever, skin diseases and snake bite. The antibacterial activity of organic solvent extracts of these plants were determined by disc diffusion and broth dilution techniques against gram-positive bacterial strains (Bacillus subtilis, Staphylococcus aureus and gram-negative bacterial strains (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa. Results revealed that the chloroform and methanol extracts of D. elata and methanol extracts of M. cerviana exhibited significant antibacterial activity against gram-positive and gram-negative strains with minimum bactericidal concentration (MBC ranging from 1.5 to 100 mg/ml. Methanol extracts of M. tridentata exhibited activity only against gram-positive bacterial strains with MBC ranging from 12.5 to 100 mg/ml. Extracts of E. axillare and S. incanum showed activity only against B. subtilis and were not bactericidal at 100 mg/ml. The most susceptible organism to the organic extracts from all the studied plants was B. subtilis and the most resistant organism was P. aeruginosa. The presence of phytochemicals such as alkaloids, tannins, triterpenoids, steroids and glycosides in the extracts of these plants supports their traditional uses as medicinal plants for the treatment of various ailments. The present study reveals potential use of these plants for developing new antibacterial compounds against pathogenic microorganisms.

  15. Negative cutaneous effects of medicinal plants in Senegal.

    Science.gov (United States)

    Niang, S O; Tine, Y; Diatta, B A; Diallo, M; Fall, M; Seck, N B; Kane, A

    2015-07-01

    Use of medicinal plants is common and widespread throughout Africa, including in Senegal. Because efficacy has been demonstrated, public policies have been instituted that have allowed plant-based therapies to have an important role in general primary care. However, little is known about the cutaneous safety of many plant-based therapies. In this 6-month prospective study all cases of dermatitis induced or aggravated by exclusive use of medicinal plants were evaluated via skin allergy testing. The results were classified and compared with the available literature. Forty-three cases of plant-therapy-associated cutaneous reactions were identified, including worsening of existing conditions (56%), recurrence of a previously resolved condition (16%) and new dermatitis arising spontaneously (28%). In the cases where the condition was new, generalized exfoliative dermatitis occurred in 42% of cases with an average time of onset of 9 days. Specific plants were identified in 65% of cases and included 18 varieties. The frequency and severity of plant-induced cutaneous reactions should be the basis for the creation of a phytovigilance programme and re-evaluation of how traditional medicine is used in the general population. When irritation occurs, identification of the responsible plant and allergy testing should be the first steps towards relieving symptoms. PMID:26207662

  16. Rice-Traditional Medicinal Plant in India

    Directory of Open Access Journals (Sweden)

    M. Umadevi

    2012-05-01

    Full Text Available Rice is rich in genetic diversity, with thousands of varieties grown throughout the world. Rice cultivation is the principal activity and source of income for about 100 million households in Asia and Africa. Rice has potential in a wide range of food categories. Besides having nutritional and medicinal benefits, the by-products of rice are equally important and beneficial. By-products from growing rice create many valuable and worthwhile products. The unedible parts, that are discarded through the milling process, and the edible part could be transformed into some of the following suggested products. Rice can be used to treat skin conditions. The rice is boiled, drained and allowed to cool and mashed. The rice is made into a paste or moulded into balls and these can be applied to boils, sores, swellings and skin blemishes. Other herbs are sometimes added to the rice balls to increase their medicinal effects. Sticky glutinous rice is often taken to treat stomach upsets, heart-burn and indigestion. Extracts from brown rice have been used to treat breast and stomach cancer and warts. They have also been used to treat indigestion, nausea and diarrhoea.

  17. Anti-osteoporotic constituents from Indian medicinal plants.

    Science.gov (United States)

    Kumar, Manmeet; Rawat, Preeti; Dixit, Preeti; Mishra, Devendra; Gautam, Abnish K; Pandey, Rashmi; Singh, Divya; Chattopadhyay, Naibedya; Maurya, Rakesh

    2010-11-01

    The objective of this study was to determine the in vitro osteogenic activities of selected medicinal plants used traditionally in India. The compounds isolated from three plants viz. Allophylus serratus, Cissus quadrangularis and Vitex negundo were evaluated for their in vitro osteogenic activities. Primary cultures of osteoblasts were used to determine the effects of these components on osteoblast functions. Five of the fourteen compounds isolated led to increase in osteoblast differentiation and mineralization. These findings lend support to the use of Allophylus serratus, Cissus quadrangularis and Vitex negundo in traditional medicine. PMID:20554183

  18. Review on medicinal uses, pharmacological, phytochemistry and immunomodulatory activity of plants.

    Science.gov (United States)

    Akram, M; Hamid, A; Khalil, A; Ghaffar, A; Tayyaba, N; Saeed, A; Ali, M; Naveed, A

    2014-01-01

    Since ancient times, plants have been an exemplary source of medicine. Researchers have discovered some important compounds from plants. The present work constitutes a review of the medicinal plants whose immunomodulant activity has been proven. We performed PUBMED, EMBASE, Google scholar searches for research papers of medicinal plants having immunomodulant activity. Medicinal plants used by traditional physicians or reported as having immunomodulant activity include Acacia concocinna, Camellia sinensis, Lawsonia inermis Linn, Piper longum Linn, Gelidium amansii, Petroselinum crispum, Plantago major and Allium sativum. Immunomodulant activities of some of these medicinal plants have been investigated. The medicinal plants documented have immunomodulant activity and should be further investigated via clinical trial. PMID:25280022

  19. Modes of Action of Herbal Medicines and Plant Secondary Metabolites

    Directory of Open Access Journals (Sweden)

    Michael Wink

    2015-09-01

    Full Text Available Plants produce a wide diversity of secondary metabolites (SM which serve them as defense compounds against herbivores, and other plants and microbes, but also as signal compounds. In general, SM exhibit a wide array of biological and pharmacological properties. Because of this, some plants or products isolated from them have been and are still used to treat infections, health disorders or diseases. This review provides evidence that many SM have a broad spectrum of bioactivities. They often interact with the main targets in cells, such as proteins, biomembranes or nucleic acids. Whereas some SM appear to have been optimized on a few molecular targets, such as alkaloids on receptors of neurotransmitters, others (such as phenolics and terpenoids are less specific and attack a multitude of proteins by building hydrogen, hydrophobic and ionic bonds, thus modulating their 3D structures and in consequence their bioactivities. The main modes of action are described for the major groups of common plant secondary metabolites. The multitarget activities of many SM can explain the medical application of complex extracts from medicinal plants for more health disorders which involve several targets. Herbal medicine is not a placebo medicine but a rational medicine, and for several of them clinical trials have shown efficacy.

  20. Antibacterial activity of selected Myanmar medicinal plants

    International Nuclear Information System (INIS)

    Thirteen plants which are traditionally used for the treatment of dysentery and diarrhoea in Myanmar were selected and tested for antibacterial activity by using agar disc diffusion technique. Polar and nonpolar solvents were employed for extraction of plants. The minimum inhibitory concentration (MIC) of the extracts with the most significant predominant activity were evaluated by plate dilution method. The plants Eugenia jambolana, Quisqualis indica, Leucaena glauca and Euphorbia splendens var. 1 were found to show significant antibacterial activity. It was also observed that extracts using nonpolar solvents did not show any antibacterial activity and extracts using polar solvents showed antibacterial activity on tested bacteria, indicating that the active chemical compound responsible for the antibacterial action must be a polar soluble compound. (author)

  1. Acanthus ilicifolius linn.-lesser known medicinal plants with significant pharmacological activities

    OpenAIRE

    Amritpal Singh; Sanjiv Duggal; Ashish Suttee

    2011-01-01

    Acanthus ilicifolius Linn. (Acanthaceae) is relatively lesser-known, yet important medicinal plant of Herbal Materia Medica. The plant is used in traditional systems of medicine, including Traditional Indian Medicine (TIM) or Ayurveda and Traditional Chinese Medicine (TCM). The plant is reported to contain phytochemicals including alkaloid and wide range of glucosides (lignan and phenylethanoid). In traditional medicine, the plant is used in the treatment of diseases ranging from sna...

  2. Ethnomedicinal Evaluation of Medicinal Plants Used against Gastrointestinal Complaints.

    Science.gov (United States)

    Tariq, Akash; Mussarat, Sakina; Adnan, Muhammad; Abd Allah, E F; Hashem, Abeer; Alqarawi, Abdulaziz Abdullah; Ullah, Riaz

    2015-01-01

    Aim of the present study was to document ethnomedicinal plants used against gastrointestinal complaints in five selected remote regions of Pakistan and to select potential medicinal plants for further in vitro and in vivo investigation. Data on ethnomedicinal plants and ethnographic profile of respondents was documented using semistructured questionnaires. The present study revealed utilization of 52 medicinal plants for the treatment of different gastrointestinal infections in studied regions. Apiaceae was the most dominant family reported to be used for the treatment of these infections (4 plants). Among all the plant parts fruit (24%), whole plants and leaves (23% each) were the most preferred plant parts used by the healers. Dosage of recipe was found to be related with the age of the patient. Highest degree of informant consensus was reported for vomiting, nausea (0.92 each), abdominal pain (0.9), and diarrhea (0.89). Withania coagulans scored highest FL value (86%) followed by Mentha longifolia and Melia azadirachta ranked second with FL value (75% each). Young generation was found to possess little traditional knowledge about utilizing plant recipes against these infections. Plants with high Fic and FL values should be subjected for further phytochemical and pharmacological investigation for scientific validation. PMID:26114117

  3. Ethnomedicinal Evaluation of Medicinal Plants Used against Gastrointestinal Complaints

    Science.gov (United States)

    Tariq, Akash; Mussarat, Sakina; Adnan, Muhammad; Abd_Allah, E. F.; Hashem, Abeer; Alqarawi, Abdulaziz Abdullah

    2015-01-01

    Aim of the present study was to document ethnomedicinal plants used against gastrointestinal complaints in five selected remote regions of Pakistan and to select potential medicinal plants for further in vitro and in vivo investigation. Data on ethnomedicinal plants and ethnographic profile of respondents was documented using semistructured questionnaires. The present study revealed utilization of 52 medicinal plants for the treatment of different gastrointestinal infections in studied regions. Apiaceae was the most dominant family reported to be used for the treatment of these infections (4 plants). Among all the plant parts fruit (24%), whole plants and leaves (23% each) were the most preferred plant parts used by the healers. Dosage of recipe was found to be related with the age of the patient. Highest degree of informant consensus was reported for vomiting, nausea (0.92 each), abdominal pain (0.9), and diarrhea (0.89). Withania coagulans scored highest FL value (86%) followed by Mentha longifolia and Melia azadirachta ranked second with FL value (75% each). Young generation was found to possess little traditional knowledge about utilizing plant recipes against these infections. Plants with high Fic and FL values should be subjected for further phytochemical and pharmacological investigation for scientific validation. PMID:26114117

  4. Laser photoacoustic detection of the essential oil vapors of thyme, mint, and anise

    Science.gov (United States)

    El-Kahlout, A. M.; Al-Jourani, M. M.; Abu-Taha, M. I.; Laine, Derek C.

    1998-07-01

    Photoacoustic studies of the vapors of the essential oils of thyme, mint and anise have been made using a line-tunable waveguide CO2 laser in conjunction with a heat-pipe type of photoacoustic vapor sample cell operated over the temperature range 20 - 180 degree(s)C. Identifying spectral fingerprint features are found in the 9 - 10 micrometers spectral region for each of the three essential oils investigated. The principal features of the photoacoustic spectrum of each essential oil are associated with the dominant chemicals present i.e. thymol in thyme oil, menthol in mint and anethole in anise.

  5. Cryopreservation of medicinal plants: role of melatonin

    Science.gov (United States)

    Many useful plant species found in Canada are of conservation concern. In vitro storage and cryopreservation techniques guarantees safety of these species and have potential applications which may result in sustainable agriculture. Shoot tips of in vitro-grown plantlets of American elm, St John’s Wo...

  6. Varieties of aromatic and medicinal plants developed in Romania

    Directory of Open Access Journals (Sweden)

    Leon jr. MUNTEAN

    1998-08-01

    Full Text Available The objectives of aromatic and medicinal plant breeding are complex: of these, the establishment of numerous traits: yield level, raw-material quality (content in active substances, uniformness of the material and reaching of technological maturity of harvesting, ability to adaptation and hardiness to diseases, pests, laying, frost, drought etc., behavior of plant raw-material during processing etc. In Romania, 20 species have been developed and authenticated, all productive and rich in active substances, weather-and pest resistant; of these, seven were authenticated between 1990 and 1997: Unirea (Cynara scolymus L., Record (Mentha crispa L., Silvia (Datura innoxia Mill., Smarald (Thymus vulgaris L., Safir (Papaver somniferum L., Tages (Tagetes patula L., Azur (Vinca minor L.. Seed and planting material with important numbers of species of aromatic and medicinal plants have been developed with years.

  7. Iranian Medicinal Plants for Diabetes Mellitus: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Mohsen Taghizadeh

    2013-01-01

    Full Text Available In the Iranian traditional medicine a significant usage of herbs is promoted for their anti-diabetic activity. The aim of this review to assess the efficacy of glucose lowering effects of medicinal plants cultivated in Iran. An electronic literature search of MEDLINE, Science Direct, EMBASE, Scopus, Web of Science, Cochrane Library Database, Ebsco and Google Scholar from database inception conducted up to May 2012. A total of 85 studies (18 humans and 67 animals examining 62 plants were reviewed. The quality of Randomized Controlled Trials (RCTs assessed by using the Jadad scale. Among the RCTs studies, the best results in glycemic control was found in Aloe vera, Citrullus colocynthus, Plantago ovata, Silybum marianum, Rheum ribes and Urtica dioica. The majority of plants that have been studied for antidiabetic activity showed promising results. However, efficacy and safety of the most plants used in the treatment of diabetes are not sufficient.

  8. Iranian medicinal plants for diabetes mellitus: a systematic review.

    Science.gov (United States)

    Rashidi, Ali Akbar; Mirhashemi, Seyyed Mehdi; Taghizadeh, Mohsen; Sarkhail, Parisa

    2013-05-01

    In the Iranian traditional medicine a significant usage of herbs is promoted for their anti-diabetic activity. The aim of this review to assess the efficacy of glucose lowering effects of medicinal plants cultivated in Iran. An electronic literature search of MEDLINE, Science Direct, EMBASE, Scopus, Web of Science, Cochrane Library Database, Ebsco and Google Scholar from database inception conducted up to May 2012. A total of 85 studies (18 humans and 67 animals) examining 62 plants were reviewed. The quality of Randomized Controlled Trials (RCTs) assessed by using the Jadad scale. Among the RCTs studies, the best results in glycemic control was found in Aloe vera, Citrullus colocynthus, Plantago ovata, Silybum marianum, Rheum ribes and Urtica dioica. The majority of plants that have been studied for antidiabetic activity showed promising results. However, efficacy and safety of the most plants used in the treatment of diabetes are not sufficient. PMID:24498803

  9. Plant biotechnology patents: applications in agriculture and medicine.

    Science.gov (United States)

    Hefferon, Kathleen

    2010-06-01

    Recent advances in agricultural biotechnology have enabled the field of plant biology to move forward in great leaps and bounds. In particular, recent breakthroughs in molecular biology, plant genomics and crop science have brought about a paradigm shift of thought regarding the manner by which plants can be utilized both in agriculture and in medicine. Besides the more well known improvements in agronomic traits of crops such as disease resistance and drought tolerance, plants can now be associated with topics as diverse as biofuel production, phytoremediation, the improvement of nutritional qualities in edible plants, the identification of compounds for medicinal purposes in plants and the use of plants as therapeutic protein production platforms. This diversification of plant science has been accompanied by the great abundance of new patents issued in these fields and, as many of these inventions approach commercial realization, the subsequent increase in agriculturally-based industries. While this review chapter is written primarily for plant scientists who have great interest in the new directions being taken with respect to applications in agricultural biotechnology, those in other disciplines, such as medical researchers, environmental scientists and engineers, may find significant value in reading this article as well. The review attempts to provide an overview of the most recent patents issued for plant biotechnology with respect to both agriculture and medicine. The chapter concludes with the proposal that the combined driving forces of climate change, as well as the ever increasing needs for clean energy and food security will play a pivotal role in leading the direction for applied plant biotechnology research in the future. PMID:20180763

  10. [Phytochemical and pharmacological advance on Tibetan medicinal plants of Corydalis].

    Science.gov (United States)

    Shang, Wei-Qing; Chen, Yue-Mei; Gao, Xiao-Li; Pu, Chi; Tu, Peng-Fei; Chai, Xing-Yun

    2014-04-01

    It was estimated that about 428 species of genus Corydalis are distributed all worldwide, with about 298, especially 10 groups and 219 species being uniquely spread in China. The genus Corydalis have been widely employed as folk medicines in China, especially as traditional Tibetan medicines, for treatment of fever, hepatitis, edema, gastritis, cholecystitis, hypertension and other diseases. The phytochemical studies revealed that isoquinoline alkaloids are its major bioactive ingredients. The extensive biological researches suggested its pharmacological activities and clinic applications against cardiovascular diseases and central nervous system, antibacterial activities, analgesic effects, anti-inflammatory, anti-oxidation and anti-injury for hepatocyte, and so on. As an effort in promoting the research of pharmacodynamic ingredients, this article presents an overview focusing on the distribution, phytochemical and pharmacological results of Corydalis species that have been applied in traditional Tibetan medicinal, hopefully to provide a reference for the new Tibetan medicine development from Corydalis plant resource. PMID:25011252

  11. INHIBITION OF TYPE I 5?-REDUCTASE BY MEDICINAL PLANT EXTRACTS

    OpenAIRE

    Patil Vijaya; Samuel Grace; Mirapurkar Shubhangi; R. Krishna Mohan; Dasgupta Debjani

    2011-01-01

    Type I 5?-reductase has been implicated in skin disorders such as acne, hirsutism and male pattern baldness and its inhibition offers a potential treatment for these disorders. The aim of this study was to investigate the inhibition of type I 5?-reductase activity by extracts from Indian medicinal plants. Plant extracts were screened and selected based on their ability to inhibit Propionibacterium acnes and Staphylococcus epidermidis. Since type I 5?-reductase metabolises testosterone to ?4-a...

  12. 3. Adaptogenic activity of a Siddha medicinal plant: Sida cordata

    OpenAIRE

    D. Gnanasekaran; C. Umamaheswara Reddy; B. Jaiprakash; N. Narayanan; Hannah Elizabeth; Y. Ravi Kiran

    2012-01-01

    The present study was carried out to investigate mechanism of adaptogenic activity of a siddha medicinal plant, Sida cordata (whole plant). Forced swimming test (FST) is a screening model for antidepressants / adaptogens. Two swimming sessions were conducted: a 15min pre-test followed 24h later by a 6min test. The total duration of immobility behaviour was recorded during the second 6min test. Mouse was judged immobile, when it remained floating in water, in an upright position making only sm...

  13. Antifungal Activity of Medicinal Plants from Jordan Environment

    Directory of Open Access Journals (Sweden)

    Amjad B. Khalil

    2005-01-01

    Full Text Available Medicinal plants collected from different locations in Jordan were tested for their antifungal activities against 5 plant pathogenic fungi: Phytophthora infestans, Fuusarium oxysporum, Rhizoctonia solani, Stemphylium solani and Mucor sp. Data of this study showed that the highest growth inhibition of all fungi was observed with Salvia indica, which gave (66.3%, of inhibitions for Stemphylium, followed by Mucor (60.5%, R. solani (51.7%, F. oxysporum (48% and P. infestans (28.8%.

  14. Varieties of aromatic and medicinal plants developed in Romania

    OpenAIRE

    Leon Sorin MUNTEAN; Leon jr. MUNTEAN

    1998-01-01

    The objectives of aromatic and medicinal plant breeding are complex: of these, the establishment of numerous traits: yield level, raw-material quality (content in active substances), uniformness of the material and reaching of technological maturity of harvesting, ability to adaptation and hardiness to diseases, pests, laying, frost, drought etc., behavior of plant raw-material during processing etc. In Romania, 20 species have been developed and authenticated, all productive and rich in acti...

  15. Direct Detection of Triterpenoid Saponins in Medicinal Plants

    OpenAIRE

    Kareru, P G; Keriko, J.M.; Gachanja, A N; G. M. Kenji

    2007-01-01

    Direct detection of saponins in medicinal plants using Fourier Transform Infrared (FTIR) spectroscopy is reported in this paper. Crude dry plant powders were mixed with potassium bromide (KBr) powder and compressed to a thin pellet for infrared examination. FTIR spectra of the test samples showed -OH, -C=O, C-H, and C=C absorptions characteristic of oleanane triterpenoid saponins. The C-O-C absorptions indicated glycoside linkages to the sapogenins. Phytochemical analysis confirmed the presen...

  16. Total Phenolics and Total Flavonoids in Selected Indian Medicinal Plants

    OpenAIRE

    Sulaiman, C. T.; Balachandran, Indira

    2012-01-01

    Plant phenolics and flavonoids have a powerful biological activity, which outlines the necessity of their determination. The phenolics and flavonoids content of 20 medicinal plants were determined in the present investigation. The phenolic content was determined by using Folin-Ciocalteu assay. The total flavonoids were measured spectrophotometrically by using the aluminium chloride colorimetric assay. The results showed that the family Mimosaceae is the richest source of phenolics, (Acacia ni...

  17. Medicinal Plants: A Source of Anti-Parasitic Secondary Metabolites

    OpenAIRE

    Michael Wink

    2012-01-01

    This review summarizes human infections caused by endoparasites, including protozoa, nematodes, trematodes, and cestodes, which affect more than 30% of the human population, and medicinal plants of potential use in their treatment. Because vaccinations do not work in most instances and the parasites have sometimes become resistant to the available synthetic therapeutics, it is important to search for alternative sources of anti-parasitic drugs. Plants produce a high diversity of secondary met...

  18. Review: Mycoendophytes in medicinal plants: Diversity and bioactivities

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    MUDASIR DAR

    2012-07-01

    Full Text Available Rai M, Gade A, Rathod D, Dar M, Varma A. 2012. Review: Mycoendophytes in medicinal plants: Diversity and bioactivities. Nusantara Bioscience 4: 86-96. Endophytes are microorganisms that reside in internal tissues of living plants without causing any negative effect. These offer tremendous potential for the exploitation of novel and eco-friendly secondary metabolites used in medicine, the pharmaceutical industry and agriculture. The present review is focused on diversity of endophytes, current national and international bioactive secondary metabolite scenario and future prospects. Endophytic fungi as novel source of potentially useful medicinal compounds are discussed along with the need to search for new and more effective agents from endophytes to combat disease problems.

  19. Antimicrobial Activity of Some Turkish Medicinal Plants

    OpenAIRE

    B. Dulger; A. Gonuz

    2004-01-01

    In this study, antimicrobial activity of Rhododendron ponticum L., Prunus laurocerasus L., Agrimonia eupatoria L., Cornus mas L., Vitis vinifera L., Punica granatum L., Anthemis cotula L., Cichorium intybus L., Viscum album L., Papaver hybridum L., Malva rotundifolia L. and Rhus coriaria L. were investigated. The ethanolic extracts of these plants were tested against Escherichia coli ATCC 11230, Staphylococcus aureus ATCC 6538P, Klebsiella pneumoniae UC57, Pseudomonas aeruginosa ATCC 27853, P...

  20. Antimicrobial Activity of Some Indian Medicinal Plants

    OpenAIRE

    Dabur, Rajesh; Gupta, Amita; Mandal, T. K.; Singh, Desh Deepak; Bajpai, Vivek; Gurav, A M; Lavekar, G S

    2007-01-01

    The antimicrobial potential of seventy-seven extracts from twenty-four plants was screened against eight bacteria and four pathogenic fungi, using microbroth dilution assay. Lowest concentration of the extract, which inhibits any visual microbial growth after treatment with p-iodonitrotetrazolium violet, was considered to be minimum inhibitory concentration (MIC). Water extracts of Acacia nilotica, Justicia zelanica, Lantana camara and Saraca asoca exhibited good activity against all the bact...

  1. Antimicrobial Activity of Some Turkish Medicinal Plants

    Directory of Open Access Journals (Sweden)

    B. Dulger

    2004-01-01

    Full Text Available In this study, antimicrobial activity of Rhododendron ponticum L., Prunus laurocerasus L., Agrimonia eupatoria L., Cornus mas L., Vitis vinifera L., Punica granatum L., Anthemis cotula L., Cichorium intybus L., Viscum album L., Papaver hybridum L., Malva rotundifolia L. and Rhus coriaria L. were investigated. The ethanolic extracts of these plants were tested against Escherichia coli ATCC 11230, Staphylococcus aureus ATCC 6538P, Klebsiella pneumoniae UC57, Pseudomonas aeruginosa ATCC 27853, Proteus vulgaris ATCC 8427, Bacillus cereus ATCC 7064, Mycobacterium smegmatis CCM 2067, Listeria monocytogenes ATCC 15313, Micrococcus luteus CCM 169, Candida albicans ATCC 10231, Rhodotorula rubra DSM 70403 and Kluyveromyces fragilis ATCC 8608 by disc diffusion method. Of the 12 plants tested, nine showed antimicrobial activity. Each plant species has unique against different microorganisms. The fruit extract of Rhus coriaria had the highest antimicrobial effect with an inhibition zone of 12-52 mm against all the bacteria, but not shown antiyeast effect. Except for the extracts of Rhus coriaria, Agrimonia eupatoria and Anthemis cotula, all additional extracts of generated inhibition zones smaller than those generated by several reference antibiotics.

  2. Distribution of Phenolics in Various Malaysian Medicinal Plants

    Directory of Open Access Journals (Sweden)

    A. Amid

    2010-01-01

    Full Text Available Phenolics, which are widely distributed in plant kingdom, appear to have desirable medicinal properties and play a major role in both plant and animal health. Some have been reported to be antitumor agents and to exhibit antiviral and antimicrobial activities, hypotensive effects and antioxidant properties. These compounds, either as isolates or in conjunction with other compounds, may be used for various health benefits. In this study, forty types of Malaysian medicinal plants were examined to develop an understanding of the distribution of phenolics and to give an assessment of the diversity present in the selected plants. The selection of plants was based on their frequent usages by local folks for their medicinal benefits. Total phenolic content was analyzed by Folin and Ciocalteau’s phenol reagent and their concentration was expressed as Gallic Acid Equivalent (GAE. All plant samples gave positive result with varying concentrations. Highest amount was obtained from Piper betle L. which had phenolic content of 8986.67 mg L-1 GAE, while the lowest concentration of 133.33 mg L-1 GAE was obtained from Canna indica Linn. This information can be used to assess taxonomic classifications, evaluate potential sources of phenolic compounds for agricultural and pharmaceutical uses and evaluate breeding program results.

  3. Probability sampling design in ethnobotanical surveys of medicinal plants

    Directory of Open Access Journals (Sweden)

    Mariano Martinez Espinosa

    2012-12-01

    Full Text Available Non-probability sampling design can be used in ethnobotanical surveys of medicinal plants. However, this method does not allow statistical inferences to be made from the data generated. The aim of this paper is to present a probability sampling design that is applicable in ethnobotanical studies of medicinal plants. The sampling design employed in the research titled "Ethnobotanical knowledge of medicinal plants used by traditional communities of Nossa Senhora Aparecida do Chumbo district (NSACD, Poconé, Mato Grosso, Brazil" was used as a case study. Probability sampling methods (simple random and stratified sampling were used in this study. In order to determine the sample size, the following data were considered: population size (N of 1179 families; confidence coefficient, 95%; sample error (d, 0.05; and a proportion (p, 0.5. The application of this sampling method resulted in a sample size (n of at least 290 families in the district. The present study concludes that probability sampling methods necessarily have to be employed in ethnobotanical studies of medicinal plants, particularly where statistical inferences have to be made using data obtained. This can be achieved by applying different existing probability sampling methods, or better still, a combination of such methods.

  4. Plants used in traditional medicine of China and Brazil

    Directory of Open Access Journals (Sweden)

    F. J. A. Matos

    1991-01-01

    Full Text Available Eventhough the rationale behind the use of medicinal plantes in Brazil and Chine is different, twenty four species are used in both countries. Scientific name, vulgar name and uses in both countries along with their chemical constituents are listed.

  5. Probability sampling design in ethnobotanical surveys of medicinal plants

    Scientific Electronic Library Online (English)

    Mariano Martinez, Espinosa; Isanete G. C., Bieski; Domingos Tabajara de Oliveira, Martins.

    2012-12-01

    Full Text Available Non-probability sampling design can be used in ethnobotanical surveys of medicinal plants. However, this method does not allow statistical inferences to be made from the data generated. The aim of this paper is to present a probability sampling design that is applicable in ethnobotanical studies of [...] medicinal plants. The sampling design employed in the research titled "Ethnobotanical knowledge of medicinal plants used by traditional communities of Nossa Senhora Aparecida do Chumbo district (NSACD), Poconé, Mato Grosso, Brazil" was used as a case study. Probability sampling methods (simple random and stratified sampling) were used in this study. In order to determine the sample size, the following data were considered: population size (N) of 1179 families; confidence coefficient, 95%; sample error (d), 0.05; and a proportion (p), 0.5. The application of this sampling method resulted in a sample size (n) of at least 290 families in the district. The present study concludes that probability sampling methods necessarily have to be employed in ethnobotanical studies of medicinal plants, particularly where statistical inferences have to be made using data obtained. This can be achieved by applying different existing probability sampling methods, or better still, a combination of such methods.

  6. Traditional uses of medicinal plants in gastrointestinal disorders in Nepal.

    Czech Academy of Sciences Publication Activity Database

    Rokaya, Maan Bahadur; Uprety, Y.; Poudel, R. C.; Timsina, B.; Münzbergová, Zuzana; Asselin, H.; Tiwari, A.; Shrestha, S. S.; Sidgel, S. R.

    2014-01-01

    Ro?. 158, Part A (2014), s. 221-229. ISSN 0378-8741 R&D Projects: GA ?R GP13-10850P Institutional support: RVO:67985939 Keywords : principal component analysis * medicinal plants * randomization test * ethnomedicine * drug development Subject RIV: EF - Botanics Impact factor: 2.998, year: 2014

  7. Evaluation of some Moroccan medicinal plant extracts for larvicidal activity.

    Science.gov (United States)

    Markouk, M; Bekkouche, K; Larhsini, M; Bousaid, M; Lazrek, H B; Jana, M

    2000-11-01

    The larvicidal properties of 16 extracts of four Moroccan medicinal plants: Calotropis procera (Wild.), Cotula cinerea (L.), Solanum sodomaeum (L.) and Solanum elaeagnifolium (CAV.) were tested against Anopheles labranchiae mosquito larvae. Among the extracts tested, nine exhibited high larvicidal activity with LC(50) (24 h) ranging from 28 to 325 ppm. PMID:11025168

  8. A pharmacological appraisal of medicinal plants with antidiabetic potential

    Directory of Open Access Journals (Sweden)

    Vasim Khan

    2012-01-01

    Full Text Available Diabetes mellitus is a complicated metabolic disorder that has gravely troubled the human health and quality of life. Conventional agents are being used to control diabetes along with lifestyle management. However, they are not entirely effective and no one has ever been reported to have fully recovered from diabetes. Numerous medicinal plants have been used for the management of diabetes mellitus in various traditional systems of medicine worldwide as they are a great source of biological constituents and many of them are known to be effective against diabetes. Medicinal plants with antihyperglycemic activities are being more desired, owing to lesser side-effects and low cost. This review focuses on the various plants that have been reported to be effective in diabetes. A record of various medicinal plants with their established antidiabetic and other health benefits has been reported. These include Allium sativa, Eugenia jambolana, Panax ginseng, Gymnema sylvestre, Momrodica charantia, Ocimum sanctum, Phyllanthus amarus, Pterocarpus marsupium, Trigonella foenum graecum and Tinospora cordifolia. All of them have shown a certain degree of antidiabetic activity by different mechanisms of action.

  9. Determination of elements in ayurvedic medicinal plants by AAS

    Science.gov (United States)

    Teerthe, Santoshkumar S.; Kerur, B. R.

    2015-08-01

    India has a rich country for the uses of Ayurvedic medicinal plants for treatment and also the north- Karnataka boasts an unparallel diversity of medicinal plants. The present study attempts to estimate and compare the level of trace and heavy metals in some selected leaves and root samples of Ayurvedic medicinal plants such as Mg, Al, K, Cr, Mn, Fe, Cu, Zn, and Cd. The samples are collected from different places of North-Karnataka regions and sample solutions prepared as the ratio of 1:25:25+950ml=1000ppm.the trace and heavy elemental concentration was estimated using Atomic Absorption Spectrometric (AAS) Method. The average concentrations of Mg, Mn, Fe and Zn, are ranging from 2ppm to 5250.2ppm and potassium (K) has more concentration as compare to all other. The other elements likes Al, Cr, Cu, and Cd were also estimed and presented in the table. Therefore, these medicinal plants are rich in some essential minerals, especially K, Mg, Mn, Fe and Zn which are essential for human health

  10. PIXE-PIGE analysis of some Indian medicinal plants

    Science.gov (United States)

    Nomita Devi, K.; Nandakumar Sarma, H.

    2010-06-01

    The quantitative estimation of various trace element concentrations in medicinal plants is necessary for determining their effectiveness in treating various diseases and for understanding their pharmacological action. Elemental concentrations of some selected medicinal plants of north east India was measured by proton induced X-ray emission (PIXE) and proton induced ?-ray emission (PIGE) techniques. PIXE measurements were carried out using 2.4 MeV collimated protons from the 3 MV tandetron accelerator of NCCCM, Hyderabad (India) while the PIGE measurements were carried out using 3 MeV protons from the same accelerator in the same laboratory. Accuracy and precision of the techniques were assured by analyzing certified reference materials in the same experimental conditions. Various elements of biological importance in man's metabolism were found to be present in varying concentrations in the studied medicinal plants and no toxic heavy metals were detected. The concentration of the various elements in the medicinal plants and their role in treating various diseases are discussed.

  11. Traditional uses of medicinal plants in gastrointestinal disorders in Nepal.

    Czech Academy of Sciences Publication Activity Database

    Rokaya, Maan Bahadur; Uprety, Y.; Poudel, R. C.; Timsina, Binu; Munzbergová, Z.; Asselin, H.; Tiwari, A.; Shrestha, S. S.; Sidgel, S. R.

    2014-01-01

    Ro?. 158, Part A (2014), s. 221-229. ISSN 0378-8741 R&D Projects: GA MŠk(CZ) ED1.1.00/02.0073 Institutional support: RVO:67179843 Keywords : medicinal plants * principal component analysis * randomization test * ethnomedicine * drug development Subject RIV: EH - Ecology, Behaviour Impact factor: 2.998, year: 2014

  12. ANTIMICROBIAL ACTIVITY OF SOME MEDICINAL PLANTS AGAINST FISH PATHOGENS

    Directory of Open Access Journals (Sweden)

    Sharma Madhuri

    2012-04-01

    Full Text Available The present article elucidates on the antimicrobial (antibacterial and antifungal activity of some medicinal plants (herbs against different microbes (e.g., bacteria and fungi. Aquaculture has been a growing activity for more than 20 years worldwide. The bacterial infections are considered the major cause of mortality in aquaculture. Among the common fish pathogenic bacteria, Streptococcus agalactiae, Lactococcus garvieae, Enterococcus faecalis (all gram-positive, Aeromonas hydrophila and Yersinia ruckeri (both gram-negative cause infectious diseases. A. hydrophila, the most common bacterial pathogen in freshwater fish, has been recognized to be the aetiological agent of many pathological conditions, including tail rot, motile Aeromonas septicemia and epizootic ulcerative syndrome as a primary pathogen. The continuous use of antimicrobial agents in aquaculture has resulted into resistant bacterial strains in the aquatic environment. Treatment of bacterial diseases with different herbs has been safely used in organic agriculture, veterinary and human medicine. Treatment with medicinal plants having antibacterial activity is a potentially beneficial alternative in the aquaculture. These herbs mitigate many of the side effects which are associated with synthetic antimicrobials. Additionally, the plant-derived phytomedicines provide a cheaper source for treatment and greater accuracy than chemotherapeutic agents. Plants have been used as traditional medicine since time immemorial to control bacterial, viral and fungal diseases. In India, 500 medicinal plant species are used against pathogenic bacteria. Recently, research has been initiated to evaluate the feasibility of herbal drugs in fish diseases. Because of the growing bacterial resistance against commercial standard and reserve antibiotics, the search for new active substances with antibacterial activity against pathogenic bacteria is of increasing importance.

  13. African medicinal plants with antidiabetic potentials: a review.

    Science.gov (United States)

    Mohammed, Aminu; Ibrahim, Mohammed Auwal; Islam, Md Shahidul

    2014-03-01

    Diabetes mellitus is one of the major health problems in Africa. The conventional oral synthetic antidiabetic drugs available to manage the disease are costly and not readily affordable to the majority of the affected population. Interestingly, the continent is endowed with a tremendous number of medicinal plants that have been explored for their folkloric treatment of diabetes mellitus. Scientific investigations have validated the antidiabetic potentials of a number of these medicinal plants but there is no repository with information on these scientifically investigated plants as a guide for future research. In this review article, all of the in vivo antidiabetic studies conducted between January 2000 and July 2013 on African plants are systematically compiled with a closer look at some relevant plants from the continent's subregions. Plants of the Asteraceae and Lamiaceae families are the most investigated, and West Africa has the highest number of investigated plants. Although promising results were reported in many cases, unfortunately, only a few studies reported the partial characterization of bioactive principles and/or mechanisms of action. It is hoped that government agencies, pharmaceutical industries, and the scientific community will have a look at some of these plants for future research and, if possible, subsequent commercialization. PMID:24535720

  14. Dhawa (Woodfordia fruticosa (L. Kurz.: A Versatile Medicinal Plant

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    Seema Rani

    2015-07-01

    Full Text Available Woodfordia fruticosa is an important medicinal plant used in traditional system of medicine since the time immemorial. It belongs to the family Lythraceae. Many organic constituents like tannins, phenols, steroids/terpenoids, carbohydrates, resins and inorganic ones including iron, aluminum, calcium, magnesium, potassium etc., have been isolated from this species in recent times. Extracts and metabolites of this plant, particularly those from flowers and leaves, possess useful pharmacological activities. Flowers are qabiz (astringent, mubarrid (refrigerant, habisud dam (haemostatic, qatil kirme shikam (anthelminthic, mujaffif (dessicative, mundamil qurooh (enhance wound healing musakkin atsh, musaffi khoon etc. It is commonly used to cure ishaal (diarrhoea, kasrate tams (menorrhagia, and bawaseer damvia (bleeding piles. Aabzan (sitz bath with decoction of this drug is useful for khuroojul miqad (prolapse of anus and sailanur rehem (leucorrhoea. The bark is also pungent, acrid, cooling, toxic, alexatric, antihelmintic, antidysentric, and uterine sedative. The bark is used in thirst, dysentery, leprosy, erysipelas and diseases of the blood. Antitumor, DNA inhibitory, immunomodulatory, antioxidant, aniproliferative, antihyperglycemic, anti-inflammatory, analgesic, cytotoxic, antibacterial, hepatoprotective, antimicrobial and anti-ulcer activities were found in various parts of this plant. Ethnopharmacological activities, chemical component and related pharmacological effects reveal that the plant Woodfordia fruticosa is an important medicinal plant having versatile beneficial pharmacological effects.

  15. Anti-halitosis plants in Iranian Traditional Medicine

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    Sh. Fahimi

    2015-04-01

    Full Text Available Halitosis is an oral health condition characterized by unpleasant odors emanating constantly from oral cavity. Almost 22-50% of the population experiences such a condition during lifespan and about half of them suffer from personal discomfort and social embarrassment. Based on the literature survey, it seems that the oral cavity is the most important origin of halitosis; therefore, this area could be considered as the best target for the treatment. Halitosis is a well-known disorder in Iranian Traditional Medicine (ITM; Avicenna and some other famous Iranian traditional physicians have described this condition in their manuscripts precisely. Herbal therapy was the major treatment suggested by Iranian scholars in which mixtures of medicinal plants were used in the form of mouthwashes and other oral formulations. In the present study, six Iranian ancient medical texts were screened for the herbs with anti-halitosis effects. Subsequent to this study, the medicinal herbs were listed and scored based on the frequency of their repetition. Moreover, the effort has been taken to provide the best scientific name for each plant as well as searching modern studies about their biological effects. In our investigation fourteen plants were obtained as the most frequent herbs for treatment of halitosis in ITM. Previous studies revealed that some of these plants have shown biological activities relating to anti-halitosis effect. The present study introduces some more plants for future studies about anti-halitosis property.

  16. POLYPHENOLS AND FLAVONOIDS OF TWELVE INDIAN MEDICINAL PLANTS

    Directory of Open Access Journals (Sweden)

    Dishant Desai

    2013-01-01

    Full Text Available In the present work, twelve Indian medicinal plants (Averrhoa carambola L., Buchanania lanzan Spr., Calophylluminophyllum L., Celastrus paniculatus Willd., Clerodendron multiflorum L., Luffa acutangula (L. Roxb., Morindacitrifolia L., Ocimum gratissimum L., Peltophorum ferrugineum (Decne., Phyllanthus fraternus Webster Syn.,Triumfetta rotundifolia Lam. and Ziziphus nummularia (Burm. F. were evaluated for their total phenol andflavonoid content. The plant material was extracted individually in different solvents by cold percolation method.Total phenol and flavonoid content was measured by using Folin-Ciocalteu’s reagent method and aluminumchloride colorimeter method respectively. Amongst the twelve plants screened, methanolic extract of P. ferrugineumhad highest total phenol and flavonoid content. These results suggest that the methanolic extract of P. ferrugineumcan be considered as a medicinal source for the treatment and prevention of many free radical related diseases

  17. Trace elements determination in ginseng and ginkgo biloba medicinal plants

    International Nuclear Information System (INIS)

    Determinations of trace elements in medicinal plants or in their extracts are of great interest since some elements are components of active constituents or they can affect the plant metabolism and consequently the formation of active constituents. In this work, inorganic components in medicinal drugs, Ginseng e Ginkgo Biloba provided from different laboratories, were analyzed by neutron activation analysis. Elements As, Br, Ca, Cl, Co Cr, Cs, Fe, K, La, Mg, Mn, Na, Rb, Sb, Sc, and Zn, were determined in these samples. Comparisons carried out between the results obtained for samples from different laboratories indicated distinct concentrations for several elements. These results may be attributed to the effect of soil composition and environmental conditions where these plants were cultivated. The precision and accuracy of the results were evaluated by analyzing reference materials Bowen's Kale from IUAPC and Cabbage from IAEA. (author)

  18. Analysis of medicinal plant extracts by neutron activation method

    International Nuclear Information System (INIS)

    This dissertation has presented the results from analysis of medicinal plant extracts using neutron activation method. Instrumental neutron activation analysis was applied to the determination of the elements Al, Br, Ca, Ce, Cl, Cr, Cs, Fe, K, La, Mg, Mn, Na, Rb, Sb, Sc and Zn in medicinal extracts obtained from Achyrolcline satureoides DC, Casearia sylvestris, Centella asiatica, Citrus aurantium L., Solano lycocarpum, Solidago microglossa, Stryphnondedron barbatiman and Zingiber officinale R. plants. The elements Hg and Se were determined using radiochemical separation by means of retention of Se in HMD inorganic exchanger and solvent extraction of Hg by bismuth diethyl-dithiocarbamate solution. Precision and accuracy of the results have been evaluated by analysing reference materials. The therapeutic action of some elements found in plant extracts analyzed was briefly discussed

  19. In vitro manipulation and propagation of medicinal plants.

    Science.gov (United States)

    Rout, G R; Samantaray, S; Das, P

    2000-04-01

    Well developed techniques are currently available to help growers meet the demand of the pharmaceutical industry in the next century. These protocols are designed to provide optimal levels of carbohydrates, organic compounds (vitamins), mineral nutrients, environmental factors (e.g. light, gaseous environment, temperature, and humidity) and growth regulators required to obtain high regeneration rates of many plant species in vitro and thereby facilitate commercially viable micropropagation. Well-defined cell culture methods have also been developed for the production of several important secondary products. An overview of the regeneration of medicinal plants by direct and indirect organogenesis and by somatic embryogenesis from various types of explants is presented, and the use of these techniques combined with other biotechnological approaches to improve medicinal plants through somaclonal variation and genetic transformation is reviewed. PMID:14538112

  20. Kenyan medicinal plants used as antivenin: a comparison of plant usage

    Directory of Open Access Journals (Sweden)

    Kisangau Daniel P

    2006-02-01

    Full Text Available Abstract The success of snake bite healers is vaguely understood in Kenya, partly due to their unknown materia medica and occult-mystical nature of their practice. A comparison is made of plants used in snake bite treatments by two culturally distinct African groups (the Kamba and Luo. Thirty two plants used for snakebite treatment are documented. The majority of the antidotes are prepared from freshly collected plant material – frequently leaves. Though knowledge of snake bite conditions etiological perceptions of the ethnic groups is similar, field ethnobotanical data suggests that plant species used by the two ethnic groups are independently derived. Antivenin medicinal plants effectively illustrate the cultural context of medicine. Randomness or the use of a variety of species in different families appears to be a feature of traditional snake bite treatments. A high degree of informant consensus for the species was observed. The study indicates rural Kenya inhabitants rely on medicinal plants for healthcare.

  1. Potential antileishmanial effect of three medicinal plants

    Directory of Open Access Journals (Sweden)

    A Eltayeb

    2012-01-01

    Full Text Available The antileishmanial activity of three organic solvent extracts and water residue of the plants: Acacia nilotica (Mimosaceae (husk, Ambrosia miratima (Astraceae (aerial shoot and Azadarichta indica (Meliaceae (leaves were tested in vitro against Leishmania donovani promastigotes. The study revealed that the extracts of A. nilotica and A. miratima have effectious antileishmanial activity at concentrations (IC 50 less than 8 ?g/ml, while the extracts of A. indica lack antileishmanial activity. The chromatographic analysis of the ethyl acetate extract of A. nilotica, the most potent extract, resulted in four TLC fractions. Three of these fractions possessed antileishmanial activity. Phytochemical study of the potent fractions revealed the presence of poly hydroxyl compounds.

  2. Artemisia herba alba: A Popular Plant with Potential Medicinal Properties

    Directory of Open Access Journals (Sweden)

    Abderrahmane Moufid

    2012-01-01

    Full Text Available Artemisia herba alba (Asteraceae, commonly known as desert or white wormwood, is used in folk medicine for treatment of various diseases. Phytochemical studies of this plant revealed the existence of many beneficial compounds such as herbalbin, cis-chryanthenyl acetate, flavonoids (hispidulin and cirsilineol, monoterpenes, sesquiterpene. The aerial parts are characterized by a very low degree of toxicity. This study reviews the main reports of the pharmacological and toxicological properties of Artemisia herba alba in addition to the main constituents. It would appear that this plant exhibits many beneficial properties. Further studies are warranted to more integrate this popular plant in human health care system.

  3. Medicinal plants for the treatment of “nervios”, anxiety, and depression in Mexican Traditional Medicine

    Scientific Electronic Library Online (English)

    S. Laura, Guzmán Gutiérrez; Ricardo, Reyes Chilpa; Herlinda, Bonilla Jaime.

    2014-10-01

    Full Text Available The term “nervios” is referred as a folk illness recognized by Mexican Traditional Medicine, and also widely reported across many countries in Latin America. “Nervios” are characterized by a “state of bodily and mental unrest”, which decreases the ability to achieve daily goals. The causes are varie [...] d; in fact, any situation that alters the emotional state or mood is interpreted as a possible triggering agent. Depression and anxiety are psychiatric disorders, which share symptoms, or can be included in the same group of disorders with “nervios”. The therapies are designed to reassure health, i.e. “calm the nerves”. For this propose, the oral administration of plants infusions is common. In this review we compile information regarding the plants used for the treatment of “nervios” in México, along with those for which reports of anxiolytic or/and antidepressive activity exist. We found 92 plant species used in folk medicine for the treatment of “nervios”, among these, sixteen have been studied experimentally. The most studied plant is Galphimia glauca Cav., Malpighiaceae, which current clinical studies have validated its efficacy in patients, and their active components, the triterpenes galphimine A, B, and C, identified. Interestingly only nine plants were found to be reported in folk medicine for the treatment of sadness or/and depression, but their antidepressant activity has not been investigated. However, among the plants used in folk medicine for treatment of “nervios”, several, as Litsea glaucescens Kunth, Lauraceae, have been proven to show antidepressant activity in experimental models, and some of their active compounds have been determined. These species could be a potential source of compounds with activity in the central nervous system.

  4. A SHORT REVIEW ON UN-EXPLORED MEDICINAL PLANT: ECBOLIUM VIRIDIE

    OpenAIRE

    *A. Elumalai; M. Chinna Eswaraiah; M. Lakshmi

    2011-01-01

    Medicinal plants are the nature’s gift to human being to make disease free healthy life. It plays a vital role to preserve our health. In our country more than 2000 medicinal plants are recognized. Ecbolium viridie (Acanthaceae) is one of the important medicinal plant in India and Malaysia. Some of its medicinal uses have been mentioned in traditional system of medicine such as ayurveda, siddha and unani. This review attempts to encompass the available literature of Ecbolium viridie with resp...

  5. A database for medicinal and aromatic plants of JK (Jammu and Kashmir) in India

    OpenAIRE

    MASOOD, AKBAR; Shafi, Mujtaba

    2005-01-01

    High throughput screening of small molecules for a given drug target is achieved using plant materials of medicinal value. Therefore, it is important to document the availability and location of such medicinal plants in the form of a database. Here, we describe a web database containing information (botanical name, common name, local name, botany, chemistry, folklore medicinal use and medicinal uses) about the medicinal and aromatic plants available i...

  6. Medicinal Plants: A Public Resource for Metabolomics and Hypothesis Development

    Directory of Open Access Journals (Sweden)

    Eve Syrkin Wurtele

    2012-11-01

    Full Text Available Specialized compounds from photosynthetic organisms serve as rich resources for drug development. From aspirin to atropine, plant-derived natural products have had a profound impact on human health. Technological advances provide new opportunities to access these natural products in a metabolic context. Here, we describe a database and platform for storing, visualizing and statistically analyzing metabolomics data from fourteen medicinal plant species. The metabolomes and associated transcriptomes (RNAseq for each plant species, gathered from up to twenty tissue/organ samples that have experienced varied growth conditions and developmental histories, were analyzed in parallel. Three case studies illustrate different ways that the data can be integrally used to generate testable hypotheses concerning the biochemistry, phylogeny and natural product diversity of medicinal plants. Deep metabolomics analysis of Camptotheca acuminata exemplifies how such data can be used to inform metabolic understanding of natural product chemical diversity and begin to formulate hypotheses about their biogenesis. Metabolomics data from Prunella vulgaris, a species that contains a wide range of antioxidant, antiviral, tumoricidal and anti-inflammatory constituents, provide a case study of obtaining biosystematic and developmental fingerprint information from metabolite accumulation data in a little studied species. Digitalis purpurea, well known as a source of cardiac glycosides, is used to illustrate how integrating metabolomics and transcriptomics data can lead to identification of candidate genes encoding biosynthetic enzymes in the cardiac glycoside pathway. Medicinal Plant Metabolomics Resource (MPM [1] provides a framework for generating experimentally testable hypotheses about the metabolic networks that lead to the generation of specialized compounds, identifying genes that control their biosynthesis and establishing a basis for modeling metabolism in less studied species. The database is publicly available and can be used by researchers in medicine and plant biology.

  7. Use of anise seed and/or ?-tocopheryl acetate in laying Japanese quail diets

    Scientific Electronic Library Online (English)

    E.V, Christaki; E.M, Bonos; P.C, Florou-Paneri.

    Full Text Available An experiment was conducted to investigate the possible use of anise (Pimpinella anisum) and/or ?-tocopheryl acetate as dietary supplements on the performance and some egg quality characteristics of laying Japanese quail. One hundred and eight Coturnix japonica quail (72 females and 36 males), 149 d [...] ays old, were randomly allocated to four equal groups with three subgroups of nine birds each (six females and three males). A commercial laying diet was fed to the control group (Group A). The remaining three groups received the same diet supplemented with anise seed at 10 g/kg (Group B) or 20 g/kg (Group C), or additional 600 mg ?-tocopheryl acetate/kg (Group D). The birds were given feed and water ad libitum for a period of 29 days, while being kept under commercial conditions. During the experiment, egg production, feed consumption and mortality were recorded daily. Also, at the end of experiment, egg weight, egg yolk, albumen and shell weight percentages, egg yolk colour (using the L*a*b* colour space), blood serum total cholesterol and triglycerides concentrations were determined. Neither the supplementation of anise nor that of ?-tocopheryl had any effect on the performance of the birds or the quality of their eggs, except for a significant change of the colour of the egg yolk. Cholesterol concentration in the serum tended to decrease with the addition of anise to the diet.

  8. ANTIOXIDANT AND PHYTOCHEMICAL POTENTIAL OF MEDICINAL PLANT KALANCHOE PINNATA

    Directory of Open Access Journals (Sweden)

    S. Chandra Mohan et al.

    2012-03-01

    Full Text Available The phytochemical analysis of the medicinal plant Kalonchoe pinnata was carried out to evaluate the antioxidant potential. Alcoholic extracts of the leaves was subjected to in vitro antioxidant activity screening models such as inhibition of lipid peroxidation, nitric oxide ,superoxide radical and hydroxyl radical scavenging activity. Ascorbic acid was used as the standard for superoxide anion radical scavenging activities. Butylated Hydroxy Toluene (BHT is used as standard for anti-lipid peroxidation activity and for nitric oxide scavenging activity Gallic acid is used as a standard. In all the models studied, the extracts showed potent antioxidant activity, thereby augmenting it into the present day system of medicine.

  9. PHARMACOGNOSTIC AND PHARMACOLOGICAL PROFILE OF TRADITIONAL MEDICINAL PLANT: MYRICA NAGI

    Directory of Open Access Journals (Sweden)

    Ashok Kumar

    2012-12-01

    Full Text Available Myrica nagi belongs to myricaceae family. It is commonly known as Bay berry (English and Kathphal (Hindi. Myrica nagi has a long history of usage in traditional medicine against various ailments. In Ayurvedic and other traditional medicinal practices the plant has been used against diseases like, fever, Cardiac debility, typhoid, diarrhoea, dysentery. Phytochemicals like glycosides, saponins tannins, flavonoids, triterpenes and sterols have been isolated. Important pharmacological activities such as hepatoprotective, antioxidant, antibacterial, antifungal, antihelmintic, antiinflammatory and antiasthmatic properties were shown by researchers. This review presents a detailed survey of the literature on various traditional uses, phytochemical and pharmacological properties of Myrica nagi.

  10. [Computer evaluation of hidden potential of phytochemicals of medicinal plants of the traditional Indian ayurvedic medicine].

    Science.gov (United States)

    Lagunin, A A; Druzhilovsky, D S; Rudik, A V; Filimonov, D A; Gawande, D; Suresh, K; Goel, R; Poroikov, V V

    2015-01-01

    Applicability of our computer programs PASS and PharmaExpert to prediction of biological activity spectra of rather complex and structurally diverse phytocomponents of medicinal plants, both separately and in combinations has been evaluated. The web-resource on phytochemicals of 50 medicinal plants used in Ayurveda was created for the study of hidden therapeutic potential of Traditional Indian Medicine (TIM) (http://ayurveda.pharmaexpert.ru). It contains information on 50 medicinal plants, their using in TIM and their pharmacology activities, also as 1906 phytocomponents. PASS training set was updated by addition of information about 946 natural compounds; then the training procedure and validation were performed, to estimate the quality of PASS prediction. It was shown that the difference between the average accuracy of prediction obtained in leave-5%-out cross-validation (94,467%) and in leave-one-out cross-validation (94,605%) is very small. These results showed high predictive ability of the program. Results of biological activity spectra prediction for all phytocomponents included in our database are in good correspondence with the experimental data. Additional kinds of biological activity predicted with high probability provide the information about most promising directions of further studies. The analysis of prediction results of sets of phytocomponents in each of 50 medicinal plants was made by PharmaExpert software. Based on this analysis, we found that the combination of phytocomponents from Passiflora incarnata may exhibit nootropic, anticonvulsant and antidepressant effects. Experiments carried out in mice models confirmed the predicted effects of Passiflora incarnata extracts. PMID:25978395

  11. Kareel plant: A natural source of medicines and nutrients

    Directory of Open Access Journals (Sweden)

    Ravi K Upadhyay

    2011-01-01

    Full Text Available Capparis decidua or kareel is an indigenous medicinal plant of India having large biodiversity in different north-western states of India. The young flower bud and fruits are used to make pickles while caper berries are used as vegetable. Plant has its wider utility in traditional folk medicine and is used as ailments to relieve variety of pains or aches such as toothache, cough and asthma heal. Plant contains few important secondary metabolites such as quercetin which act as melanogenesis stimulator and also increase tyrosinase protein expression. Capparis sp. seeds contain lectin that exhibit potent anti HIV-1 reverse transcriptase inhibition activity and also inhibits proliferation of hepatoma HepG2 and breast cancer MCF-7 cells. It shows anti-rheumatic, anti-diabitic, anti-arthritis and anti-gout agent. C. decidua contains generous quantities of alkaloids, fatty acids, terpenes, vitamins, fibre and oils that show greater medicinal and nutritive value. It also contains saccharides, glycosides, flavonoids, volatile oils, sterols and steroids, which showed multiple pharmacological effects such as anti-inflammatory, odynolysis, anti-fungus, hepatoprotective effect, hypoglycemic activity, anti-oxidation, anti-hyperlipemia, anti-coagulated blood, smooth muscle stimulation, anti-stress reaction. Cadabicine an alkaloid that occurs in leaves shows anti-parasitic activity, while root bark and pulp are used to kill helminthes. Due to enzymatic inhibition plant extract shows the ability to control Leishmania major and L. infantum, L. donovani, L. braziliensis, Crithidia fasciculata and Herpetomonas muscarum infection. In the present review article both medicinal and nutraceutical properties of C decidua have been described in detail and special emphasis is given on its sustainable use of plant and its conservation in natural habitat.

  12. Medicinal plants with teratogenic potential: current considerations

    Scientific Electronic Library Online (English)

    Kassiane Cristine da Silva, Costa; Suzana Barbosa, Bezerra; Clevanice Moreira, Norte; Luciana Macatrão Nogueira, Nunes; Tiago Moreira de, Olinda.

    2012-09-01

    Full Text Available Este trabalho busca as implicações atuais sobre o uso de plantas medicinais durante a gravidez, alertando sobre aquelas que devem ser evitadas nesse período por serem potencialmente abortivas e/ou teratogênicas. Para tanto, foram realizadas buscas nas bases de dados Sciencedirect, Scielo e Google sc [...] holar, adotando-se como critérios de inclusão capítulos de livros e/ou artigos completos (com abstract) e disponíveis, em português, inglês ou espanhol, publicados de 1996 a 2011. Após uma pré-seleção de 83 artigos, 49 bibliografias foram utilizadas na confecção final do artigo, sendo 25 provenientes da base de dados Scielo, 18 do Sciencedirect e 06 do Google scholar. A partir dos artigos estudados, identificaram-se as quatro plantas mais utilizadas como emenagogas/abortivas por pacientes do Serviço de Pré-Natal do SUS: senne, arruda, boldo e buchinha-do-norte ou cabacinha. Assim, é possível concluir que, muitas vezes, a população se utiliza da máxima "se é natural, não faz mal" para fazer uso irracional de produtos naturais, sem a correta orientação, acreditando que esses produtos sejam incapazes de provocar qualquer dano. Esse uso é ainda mais preocupante quando realizado por idosos, gestantes e crianças. Em relação à segurança do uso desses produtos, algumas informações e dados confiáveis ainda são escassos ou contraditórios. Abstract in english The aim of this study was to present the implications of the use of herbs during pregnancy, pointing out those that should be avoided during this condition because of their abortifacient and/or teratogenic potential. We carried out searches in the databases ScienceDirect, Scielo and Google Scholar, [...] adopting as criteria for inclusion: book chapters and/or complete articles (with abstract), available in English, Portuguese or Spanish, published from 1996 to in 2011. After a pre-selection of 83 articles, 49 bibliographies were used in the manufacturing end of the article, where 25 were from the Scielo database, 18 from ScienceDirect and 6 from Google Scholar. From the articles studied, we identified the four most commonly used plants as emmenagogue/abortifacient agents by patients of the Department of Prenatal SUS: senne, arruda, boldo and buchinha-do-norte or cabacinha. Thus, we conclude that people often adhere to the maxim "if it's natural, it does no harm" in their rational use of natural products, without the right guidance, believing that these products are safe to use. This usage is even more worrisome among the elderly, pregnant women and children. Regarding the safety of these products, some information and reliable data are scarce or contradictory.

  13. The Medicinal Plants of the Woodlands in northern Malawi (Karonga District)

    OpenAIRE

    Bundschuh, Tina Vanadis; Hahn, Karen; Wittig, Rüdiger (Prof. Dr.)

    2011-01-01

    In rural Africa, the use of wild plants for medicinal purposes is widespread. Many publications provide regional checklists of medicinal plants, but only a few of these checklists cover Malawi. In the Karongo district, northern Malawi, 30 traditional healers and birth attendants were interviewed regarding their use of woody medicinal plants. This survey reveals that 71 of the 102 woody species that are found in this area are used for a variety of treatments. These medicinal plants are most co...

  14. The Role and Place of Medicinal Plants in the Strategies for Disease Prevention

    OpenAIRE

    Sofowora, Abayomi; Ogunbodede, Eyitope; Onayade, Adedeji

    2013-01-01

    Medicinal plants have been used in healthcare since time immemorial. Studies have been carried out globally to verify their efficacy and some of the findings have led to the production of plant-based medicines. The global market value of medicinal plant products exceeds $100 billion per annum. This paper discusses the role, contributions and usefulness of medicinal plants in tackling the diseases of public health importance, with particular emphasis on the current strategic approaches to dise...

  15. A review on antiulcer activity of few Indian medicinal plants.

    Science.gov (United States)

    Vimala, G; Gricilda Shoba, F

    2014-01-01

    Ulcer is a common gastrointestinal disorder which is seen among many people. It is basically an inflamed break in the skin or the mucus membrane lining the alimentary tract. Ulceration occurs when there is a disturbance of the normal equilibrium caused by either enhanced aggression or diminished mucosal resistance. It may be due to the regular usage of drugs, irregular food habits, stress, and so forth. Peptic ulcers are a broad term that includes ulcers of digestive tract in the stomach or the duodenum. The formation of peptic ulcers depends on the presence of acid and peptic activity in gastric juice plus a breakdown in mucosal defenses. A number of synthetic drugs are available to treat ulcers. But these drugs are expensive and are likely to produce more side effects when compared to herbal medicines. The literature revealed that many medicinal plants and polyherbal formulations are used for the treatment of ulcer by various ayurvedic doctors and traditional medicinal practitioners. The ideal aims of treatment of peptic ulcer disease are to relieve pain, heal the ulcer, and delay ulcer recurrence. In this review attempts have been made to know about some medicinal plants which may be used in ayurvedic as well as modern science for the treatment or prevention of peptic ulcer. PMID:24971094

  16. An Evidence-based Review on Medicinal Plants used for the Treatment of Peptic Ulcer in Traditional Iranian Medicine

    OpenAIRE

    Zahra Abbasabadi; Roja Rahimi; Mohammad Hosein Farzaei; Mohammad Abdollahi

    2013-01-01

    Many medicinal plants have been identified in Traditional Iranian Medicine (TIM) for the treatment of Peptic Ulcer (PU) but they are still unknown to scientific community. In the present study anti PU activity of these remedies were systematically reviewed and identified. For this purpose, medicinal plants proposed for the management of PU in TIM were collected from TIM sources and they were searched in modern medical databases like PubMed, Scirus, Sciencedirect and Google Scholar to find stu...

  17. An empirical investigation on factors influencing on exporting medicinal plants

    Directory of Open Access Journals (Sweden)

    Hoda Nosouzi

    2013-06-01

    Full Text Available During the past few years, there have been growing interests on developing medicinal plant industry. This paper presents an empirical study on important factors influencing medicinal plant for developing exports in Iran. The proposed study of this paper designs a questionnaire and distributes it among 310 regular customers who are involved in this industry in city of Tehran, Iran. Cronbach alpha has been calculated as 0.802. In addition, Kaiser-Meyer-Olkin Measure of Samplng =KMO test was also computed and it was about 0.66, which is above the minimum acceptable limit of 0.5. The study uses Scree plot to determine important factors and there are eight factors including environmental issues, export supportive issues, potentials for export, business plan, export plan, structural barriers, competition capability and strategy.

  18. ANTIOXIDANT AND PHYTOCHEMICAL POTENTIAL OF MEDICINAL PLANT KALANCHOE PINNATA

    OpenAIRE

    S. Chandra Mohan et al.

    2012-01-01

    The phytochemical analysis of the medicinal plant Kalonchoe pinnata was carried out to evaluate the antioxidant potential. Alcoholic extracts of the leaves was subjected to in vitro antioxidant activity screening models such as inhibition of lipid peroxidation, nitric oxide ,superoxide radical and hydroxyl radical scavenging activity. Ascorbic acid was used as the standard for superoxide anion radical scavenging activities. Butylated Hydroxy Toluene (BHT) is used as standard for anti-lipid pe...

  19. Medicinal Plants for the Treatment of Hypertrophic Scars

    OpenAIRE

    Ye, Qi; Su-juan WANG; Chen, Jian-Yu; Rahman, Khalid; XIN, HAI-LIANG; Hong ZHANG

    2015-01-01

    Hypertrophic scar is a complication of wound healing and has a high recurrence rate which can lead to significant abnormity in aesthetics and functions. To date, no ideal treatment method has been established. Meanwhile, the underlying mechanism of hypertrophic scarring has not been clearly defined. Although a large amount of scientific research has been reported on the use of medicinal plants as a natural source of treatment for hypertrophic scarring, it is currently scattered across a wide ...

  20. SNAKE BITES: ROLE OF MEDICINAL PLANTS IN MANAGEMENT

    OpenAIRE

    Bahekar, Satish E.; Ranjana S Kale

    2013-01-01

    Snake bites possess significant amount of mortality as well as morbidity all over the world including India. Despite various species of snakes, only few of these can be potentially lethal to humans. Snake antivenom being only therapeutic option available in snake bite management, but has many drawbacks in actual clinical practice like species specificity, difficulty in availability, affordability and ideal storage conditions. The medicinal plants, available locally and used widely by traditio...

  1. SYNERGISTIC EFFET OF INDIGENOUS MEDICINAL PLANT EXTRACTS ON PSORIASIS

    OpenAIRE

    anusha swarna

    2013-01-01

    AbstractThe present paper deals with evaluation of synergistic effect of two medicinal plants, Ponamia pinnata Linn and Psoralea corylifolia Linn. Extraction was carried out with soxhlet apparatus using the solvent ethanol. The anti-psoriatic activity was done by Induction of psoriasiform changes in guinea pig by propranolol method and Rat UV B rays Photo dermatitis model for psoriasis. Antimicrobial activity by plate hole diffusion method. Ethanolic extract exhibited significant effect of an...

  2. HISTOCHEMICAL INVESTIGATION OF TWO MEDICINAL PLANTS IN MAHARASHTRA

    OpenAIRE

    V B Kadam; S S TAMBE; Fatima Sumia; R K Momin

    2013-01-01

    The histochemical studies of leaves and wood of Butea monosperma ­Lam and Madhuca indica Gmel. are medicinal important plants in Maharashtra. For histochemical studies the free hand sections of leaves and wood were taken and treated with the respective reagent in localize components, viz. starch, protein, tannin, saponin, fat, glucosides and alkaloids in the tissues. Key words: Histochemistry, starch, protein, tannin, saponin, fat, glucosides and alkaloids

  3. Synthesis and characterization of nanoparticles capped with medicinal plant extracts

    Science.gov (United States)

    Rekulapally, Sujith R.

    In this study, synthesis, characterization and biological application of series nanometal (silver, Ag) and nanometal oxide (titania, TiO2) were carried out. These nanomaterials were prepared using wet-chemistry method and then coated using natural plant extract. Three medicinal plants, namely Zingiber officinale (Ginger), Allium sativum (Garlic) and Capsicum annuum (Chili) were chosen as grafting agent to decrease the side-effects and increase the efficiency of NPs towards living organism. Extraction conditions were controlled under 60-100 °C for 8 hrs. Ag and TiO2 NPs were fabricated using colloidal chemistry and variables were controlled at ambient condition. The band gap of TiO2 NPs used as disinfectant was also modified through coating the medicinal plant extracts. The medicinal plant extracts and coated NPs were measured using spectroscopic methods. Ultraviolet-visible spectra indicated the Ag NPs were formed. The peak at 410 nm resulted from the electrons transferred from their ground to the excited state. The broadened full width at half maximum (FWHM) suggested the ultrafine particles were obtained. The lipid soluble compounds, phenols, tri-terpenoids, flavanoids, capsaicinoids, flavonoids, carotenoids, steroids steroidal glycosides, and vitamins were determined from the high performance liquid chromatographical analyses. X-ray powder diffraction indicated that the face-centered cubic Ag (PDF: 00-004-0783, a = 4.0862A, a = 90°) and anatase TiO2 (PDF: 01-08-1285, a = 3.7845, c = 9.5143A, a = 90°) were obtained using colloidal chemistry. Bactericidal activity indicated that these core-shelled TiO 2 were effective (MBC=0.6 ppm, within 30 mins) at inactivating Gram-positive and Gram-negative bacteria. It is proposed that the medicinal extracts enhanced the potency of NPs against bacteria. From our previous study, the Ag NPs were highly effective at inactivating both bacteria.

  4. Sterol contents from some fabaceous medicinal plants of Rajasthan desert

    Directory of Open Access Journals (Sweden)

    B.B.S.Kapoor

    2013-12-01

    Full Text Available Evaluation of sterol contents from three selected medicinal plant species of Fabaceae family growing in Rajasthan Desert was carried out. The roots, shoots and fruits of Clitoria ternatea, Sesbania bispinosa and Tephrosia purpurea were analysed for sterol contents. ?- Sitosterol and Stigmasterol were isolated and identified. Maximum sterol contents were observed in shoots of Sesbania bispinosa (0.29 mg/g.d.w., whereas minimum in roots of Tephrosia purpurea(0.15mg/g.d.w.

  5. Micropropagation of an antidiabetic medicinal plant, Artemisia pallens

    OpenAIRE

    NATHAR, Varsha Nitin; YATOO, Ghulam Mohiuddin

    2014-01-01

    Artemisia pallens Wall. is an important aromatic medicinal plant used as a folk remedy for the treatment of diabetes mellitus. The present study was initiated to explore in vitro propagation of Artemisia pallens using different explants on Murashige and Skoog (MS) media supplemented with varying concentrations and combinations of growth regulators. Highest callogenic response (100%) was shown by shoot tip explants with 2 mg/L 2,4-dichlorophenoxyacetic acid. The highest number of shoots (14.25...

  6. Content of trace metals in medicinal plants and their extracts

    OpenAIRE

    Kosti? Danijela; Miti? Snežana; Zarubica Aleksandra; Miti? Milan; Veli?kovi? Jasmina; Ran?elovi? Saša

    2011-01-01

    The heavy metals (Fe, Cu, Zn and Mn) contents of selected plant species, grown in Southeast region of Serbia, that are traditionally used in alternative medicine were determined. Among the considered metals, iron content was the highest one and varied from 137.53 up to 423.32 mg/kg, while the contents of Cu, Zn and Mn were remarkably lower, and ranged from 8.91 to 62.20 mg/kg. In addition, an analysis of plants extracts showed a significant transfer of heavy metals during extraction pro...

  7. Screening of Zulu medicinal plants for prostaglandin-synthesis inhibitors.

    Science.gov (United States)

    Jäger, A K; Hutchings, A; van Staden, J

    1996-06-01

    Aqueous and ethanolic extracts of 39 plants used in traditional Zulu medicine to treat headache or inflammatory diseases were screened for prostaglandin-synthesis inhibitors. Extracts were tested in an in vitro assay for cyclooxygenase inhibitors. In general, ethanolic extracts caused higher inhibition than aqueous extracts. Two-thirds of the plants screened had high inhibitory activity. The highest inhibition was obtained with ethanolic extracts of Bidens pilosa, Eucomis autumnalis, Harpephyllum caffrum, Helichrysum nudifolium, Leonotis intermedia, L. leonorus, Ocotea bullata, Rumex saggitatus, Solanum mauritianum, Synadenium cupulare and Trichilia dregeana. PMID:8735453

  8. Antimicrobial Activity of Some Medicinal Plants Against Candida albicans

    Directory of Open Access Journals (Sweden)

    Dhia Hassawi

    2006-01-01

    Full Text Available Four extract amounts (200, 150, 100 and 50 mg mL-1 from twelve medicinal plant species that belong to six genera (Achillea, Salvia, Convolvulus, Plantago, Anthemis and Artemisia were tested against Candida albicans. The antimicrobial activity was carried out by using the hole-plate diffusion method. The effect of plant species, extract amounts and their interaction were highly significant. Achillea santolina, Salvia dominica and Salvia officinalis inhibited the growth of Candida albicans at all tested extract amounts. The extracts of (Salvia spinosa, Convolvulus althaeoides and Plantago lanceolata showed no activity against Candida albicans.

  9. IN VITRO ANTIHELMINTIC ACTIVITY OF SOME MEDICINAL PLANTS: A REVIEW

    Directory of Open Access Journals (Sweden)

    Manish H. Bachani

    2012-09-01

    Full Text Available Helminthiasis is infestation with one or more intestinal parasitic worms roundworms, whipworms , or hookworms in humans and animals. Presently, many synthetic drugs are available to treat Helminthiasis infection effectively, but suffer from number of side effects like abdominal pain, dizziness, headache, fever, nausea, vomiting, or temporary hair loss. Moreover, drug resistance is also another factor concerned with the use of these drugs. Thus, Herbal drugs need to be introduced as large number of medicinal plants are known for their antihelmintic activity with fewer or no side effects and are used by the ethnic groups across different parts of the world. But these medicinal plants need to be screened first for their in vitro and in vivo activity before putting them in use. Thus, many of these herbs have been scrutinized for their pharmacological and pre clinical studies. The present article describes review of promising in vitro efficacy of some medicinal plants having antihelmintic activity, which can be helpful in investigation and discovery of novel herbal drugs.

  10. A REVIEW ON THE MEDICINAL PLANT PSIDIUM GUAJAVA LINN. (MYRTACEAE

    Directory of Open Access Journals (Sweden)

    Shruthi Shirur Dakappa

    2013-03-01

    Full Text Available Psidium guajava is an important food crop and medicinal plant available in tropical and subtropical countries, widely used in food and folk medicines around the world. It contains important phytoconstituents such as tannins, triterpenes, flavonoid: quercetin, pentacyclic triterpenoid: guajanoic acid, saponins, carotenoids, lectins, leucocyanidin, ellagic acid, amritoside, beta-sitosterol, uvaol, oleanolic acid and ursolic acid. In view of the immense medicinal importance of the plant, this review is an effort to compile all the information reported on its ethanobotanical, phytochemical and pharmacological activities. The present work attempts to generate interest among the masses regarding its potential in preventing and treating several common diseases. Many pharmacological studies have demonstrated the ability of this plant to exhibit antioxidant, hepatoprotective, anti-allergy, antimicrobial, antigenotoxic, antiplasmodial, cytotoxic, antispasmodic, cardioactive, anticough, antidiabetic, antiinflamatory and antinociceptive activities, supporting its traditional uses. Suggesting a wide range of clinical applications for the treatment of infantile rotaviral enteritis, diarrhoea and diabetes. Key words: ethanobotany, myrtaceae, pharmacology, physicochemical, phytochemical, Psidium guajava

  11. Plant Secondary Metabolites in some Medicinal Plants of Mongolia Used for Enhancing Animal Health and Production

    Directory of Open Access Journals (Sweden)

    Makkar, HPS.

    2009-01-01

    Full Text Available The levels and activities of a number of plant secondary metabolites (PSMs are known to increase in response to increase in stress. The Mongolian plants considered to possess medicinal properties may contain novel compounds since they are exposed to severe conditions; such plants could become good candidates for modern drug discovery programmes. Information on distribution, palatability to livestock and opinion of local people on their nutritive and medicinal values was compiled for 15 plant materials from 14 plant species considered important for medicinal purposes. These plants were evaluated for nutritive value and PSMs: tannins, saponins, lectins, alkaloids and cyanogens. High levels of tannins were found in roots of Bergenia crassifolia and in leaves of B. crassifolia, Vaccinium vitisidaea and Rheum undulatum. High lectin activity (haemagglutination was present in B. crassifolia roots, and leaves of R. undulatum, Iris lacteal and Thymus gobicus contained weak lectin activity. Tanacetum vulgare, Serratula centauroids, Taraxacum officinale and Delphinum elatum leaves contained saponin activity (haemolysis. Alkaloids and cyanogens were not present in any of the samples. The paper discusses the known medicinal uses of these plants in light of the PSMs levels, and identifies plant samples for future applications in human and livestock health, welfare and safety.

  12. Elemental investigation of Syrian medicinal plants using PIXE analysis

    Science.gov (United States)

    Rihawy, M. S.; Bakraji, E. H.; Aref, S.; Shaban, R.

    2010-09-01

    Particle induced X-ray emission (PIXE) technique has been employed to perform elemental analysis of K, Ca, Mn, Fe, Cu, Zn, Br and Sr for Syrian medicinal plants used traditionally to enhance the body immunity. Plant samples were prepared in a simple dried base. The results were verified by comparing with those obtained from both IAEA-359 and IAEA-V10 reference materials. Relative standard deviations are mostly within ±5-10% suggest good precision. A correlation between the elemental content in each medicinal plant with its traditional remedial usage has been proposed. Both K and Ca are found to be the major elements in the samples. Fe, Mn and Zn have been detected in good levels in most of these plants clarifying their possible contribution to keep the body immune system in good condition. The contribution of the elements in these plants to the dietary recommended intakes (DRI) has been evaluated. Advantages and limitations of PIXE analytical technique in this investigation have been reviewed.

  13. MASS MULTIPLICATION OF THE INDIAN MEDICINAL PLANT Tylophora Indica (Burm.f.) Merr

    OpenAIRE

    Dhandapani, R.; Balu, S.

    2002-01-01

    Tylophora indica (Burm.f) Merr. (ASCLEPIDACEAE) is an important Indian medicinal plant. It is called “ASTHMA KODI” OR “NANJARUPPAN” IN Tamil in the Siddha system of medicine. Tamil medical literature reveal that it is an ideal plant medicine for respiratory problems and is also a cardiac tonic. For medicinal purposes it is collected only from the wild. It has not yet been brought under cultivation. Its taxonomy, morphology, ecology and medicinal uses were studied. Since, tissue-culture is a c...

  14. A meta-analysis of medicinal plants to assess the evidence for toxicity

    OpenAIRE

    Chen, Sarah; Vieira, Amandio

    2010-01-01

    Toxicity of phytochemicals, plant-based extracts and dietary supplements, and medicinal plants in general, is of medical importance and must be considered in phytotherapy and other plant uses. We show in this report how general database analyses can provide a quantitative assessment of research and evidence related to toxicity of medicinal plants or specific phytochemicals. As examples, several medicinal plants are analyzed for their relation to nephrotoxicity and hepatotoxicity. The results ...

  15. Acanthus ilicifolius linn.-lesser known medicinal plants with significant pharmacological activities

    Directory of Open Access Journals (Sweden)

    Amritpal Singh

    2011-04-01

    Full Text Available

    Acanthus ilicifolius Linn. (Acanthaceae is relatively lesser-known, yet important medicinal plant of Herbal Materia Medica. The plant is used in traditional systems of medicine, including Traditional Indian Medicine (TIM or Ayurveda and Traditional Chinese Medicine (TCM. The plant is reported to contain phytochemicals including alkaloid and wide range of glucosides (lignan and phenylethanoid. In traditional medicine, the plant is used in the treatment of diseases ranging from snake bite to skin diseases. Laboratory investigations on extracts of the plant have demonstrated significant pharmacological activities like antioxidant, anticarcinogenic, anti-osteporotic and hepatoprotective. The review analyses traditional medicinal usage, and phyto-pharmacological investigations done on the medicinal plant.

    Keywords: Acanthus ilicifolius, traditional medicine, phytochemistry, pharmacology, glucosides

  16. Screening of medicinal plant extracts for antioxidant activity.

    Science.gov (United States)

    Lee, Si Eun; Hwang, Hyun Jin; Ha, Jung-Sun; Jeong, Han-Seung; Kim, Jeong Hee

    2003-05-30

    The methanol extracts of nine medicinal plants traditionally used in Chinese medicine were screened for antioxidant activity versus resveratrol, which has been shown to protect cells from oxidative damage [Toxicol. Lett. 102 (1998) 5]. Most of the plant extracts used in this study inhibited the H(2)O(2)-induced apoptosis of Chinese hamster lung fibroblast (V79-4) cells. The extracts of Areca catechu var. dulcissima, Paeonia suffruticosa, Alpinia officinarum, Glycyrrhiza uralensis and Cinnamomun cassia strongly enhanced viability against H(2)O(2)-induced oxidative damage in V79-4 cells. Relatively high levels of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity were detected in extracts of Areca catechu var. dulcissima, Paeonia suffruticosa and Cinnamomun cassia (IC(50) < 6.0 microg/ml). The activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) were dose-dependently enhanced in V79-4 cells treated with most of the plant extracts. The extracts of Areca catechu var. dulcissima showed higher antioxidant activity than resveratrol in all experiments. These results suggest that the plant extracts prevent oxidative damage in normal cells probably because of their antioxidant characteristics. PMID:12738032

  17. Mutagenic screening of some commonly used medicinal plants in Nigeria.

    Science.gov (United States)

    Akintonwa, Alade; Awodele, Olufunsho; Afolayan, Gbenga; Coker, Herbert A B

    2009-09-25

    The uses of medicinal plants have always been part of human culture. The World Health Organization estimates that up to 80% of the world's population relies on traditional medicinal system for some aspect of primary health care. However, there are few reports on the toxicological properties of most medicinal plants especially, their mutagenicity and carcinogenicity. Therefore, this research is to determine the mutagenic potentials of Morinda lucida [Oruwo (Root)], Azadirachta indica [Dongoyaro (Leaf)], Terapluera tetraptera [Aridan (Fruit)], Plumbago zeylanica [Inabiri (Root)], Xylopia aethiopica [Erunje (Fruit)], Newbouldia laevis [Akoko (Leaf)], Alstonia boonei [Ahun (Bark)], Enantia chlorantha [Awopa (Bark)], and Rauvolfia vomitoria [Asofeyeje (Root)] using the Allium cepa Linn. model and the modified Ames assay. Allium cepa model was used to determine the mean root length, mitotic index and chromosomal aberrations effects of these plants on onion bulbs using 0.1, 1, 5 and 10mg/ml concentration of the plant extracts. The modified Ames test which is a modification of the standard Ames test as described by Ames et al. [Ames, B.N., McCann, J., Yamasaki, E., 1975. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenicity test. Mutation Research 31, 347-364] was done using Escherichia coli (0157:H7) that has the phenotypic characteristics of glucose and lactose fermentation, motile, urease negative, indole positive and citrate negative. The results obtained from Allium cepa assay showed increasing root growth inhibition with increased concentration, decreasing mitotic index with increased concentration and chromosomal aberrations. The modified Ames test showed an alteration in the biochemical characteristics of Escherichia coli (0157:H7) for all plants except Rauvolfia vomitoria and Plumbago zeylanica. Three of the medicinal plants altered at least three of the normal biochemical characteristics thus demonstrating mutagenic potentials. The results of internationally accepted Allium cepa were comparable with the modified Ames test. However, a long term in vivo and dose dependent study should be carried out to validate these results and the findings should be communicated to drug and food regulatory body and also to the general public. PMID:19619631

  18. Rapid Identification and Verification of Indirubin-Containing Medicinal Plants.

    Science.gov (United States)

    Hu, Zhigang; Tu, Yuan; Xia, Ye; Cheng, Peipei; Sun, Wei; Shi, Yuhua; Guo, Licheng; He, Haibo; Xiong, Chao; Chen, Shilin; Zhang, Xiuqiao

    2015-01-01

    Indirubin, one of the key components of medicinal plants including Isatis tinctoria, Polygonum tinctorium, and Strobilanthes cusia, possesses great medicinal efficacy in the treatment of chronic myelocytic leukemia (CML). Due to misidentification and similar name, materials containing indirubin and their close relatives frequently fall prey to adulteration. In this study, we selected an internal transcribed spacer 2 (ITS2) for distinguishing these indirubin-containing species from five of their usual adulterants, after assessing identification efficiency of matK, rbcL, psbA-trnH, and ITS2 among these species. The results of genetic distances and neighbor-joining (NJ) phylogenetic tree indicated that ITS2 region is a powerful DNA barcode to accurately identify these indirubin-containing species and discriminate them from their adulterants. Additionally, high performance liquid chromatography (HPLC) was used to verify indirubin in different organs of the above species. The results showed that indirubin had been detected in the leaves of Is. tinctoria, P. tinctorium, S. cusia, and Indigo Naturalis (made from their mixture), but not in their roots, or in the leaves of their adulterants. Therefore, this study provides a novel and rapid method to identify and verify indirubin-containing medicinal plants for effective natural treatment of CML. PMID:26089942

  19. Chemometric evaluation of trace elements in Brazilian medicinal plants

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Paulo S.C. da; Francisconi, Lucilaine S.; Goncalves, Rodolfo D.M.R., E-mail: pscsilva@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Centro do Reator de Pesquisas

    2013-07-01

    The growing interest in herbal medicines has required standardization in order to ensure their safe use, therapeutic efficacy and quality of the products. Despite the vast flora and the extensive use of medicinal plants by the Brazilian population, scientific studies on the subject are still insufficiency In this study, 59 medicinal plans were analyzed for the determination of As, Ba, Br, Ca, Cl, Cs, Co, Cr, Fe, Hf, K, Mg, Mn, Na, Rb, Sb, Sc, Se, Ta, Th, U, Zn and Zr by neutron activation analysis and Cu, Ni, Pb, Cd and Hg by atomic absorption. The results were analyzed by chemometric methods: correlation analysis, principal component analysis and cluster analysis, in order to verify whether or not there is similarity with respect to their mineral and trace metal contents. Results obtained permitted to classify distinct groups among the analyzed plants and extracts so that these data can be useful in future studies, concerning the therapeutic action the elements here determined may exert. (author)

  20. Chemometric evaluation of trace elements in Brazilian medicinal plants

    International Nuclear Information System (INIS)

    The growing interest in herbal medicines has required standardization in order to ensure their safe use, therapeutic efficacy and quality of the products. Despite the vast flora and the extensive use of medicinal plants by the Brazilian population, scientific studies on the subject are still insufficiency In this study, 59 medicinal plans were analyzed for the determination of As, Ba, Br, Ca, Cl, Cs, Co, Cr, Fe, Hf, K, Mg, Mn, Na, Rb, Sb, Sc, Se, Ta, Th, U, Zn and Zr by neutron activation analysis and Cu, Ni, Pb, Cd and Hg by atomic absorption. The results were analyzed by chemometric methods: correlation analysis, principal component analysis and cluster analysis, in order to verify whether or not there is similarity with respect to their mineral and trace metal contents. Results obtained permitted to classify distinct groups among the analyzed plants and extracts so that these data can be useful in future studies, concerning the therapeutic action the elements here determined may exert. (author)

  1. Analysis of five trace elements in medicinal plants used in ayurvedic medicine to control diabetes

    International Nuclear Information System (INIS)

    Analysis of Chromium, Vanadium, Iron, Copper and Zinc known to influence the glucose/ insulin system was carried out in 36 different Ayurvedic medicinal plant species used to control and treat diabetes in Sri Lanka using the Energy Dispersive X ray fuorescence technique. Chromium, which is an essential nutrient in carbohydrate and lipid metabolism, was measured in 7 plant species ranging from 13-82 ppm dry ash weight. Polarographic analysis showed that one fourth of the chromium was present in the trivalent state in all seven plant species namely Ficus banghalensis, Ficus racemosa, Musa pradisiaca, Coccinea grandis, Benincasa hispida, Pongamia pinnata and Acacia nilotica. The importance of the other metals in the control of diabetes is also briefly discussed

  2. Medicinal plants used for traditional veterinary in the Sierras de Córdoba (Argentina: An ethnobotanical comparison with human medicinal uses

    Directory of Open Access Journals (Sweden)

    Luján María C

    2011-08-01

    Full Text Available Abstract Background This is a first description of the main ethnoveterinary features of the peasants in the Sierras de Córdoba. The aim of this study was to analyze the use of medicinal plants and other traditional therapeutic practices for healing domestic animals and cattle. Our particular goals were to: characterize veterinary ethnobotanical knowledge considering age, gender and role of the specialists; interpret the cultural features of the traditional local veterinary medicine and plant uses associated to it; compare the plants used in traditional veterinary medicine, with those used in human medicine in the same region. Methods Fieldwork was carried out as part of an ethnobotanic regional study where 64 informants were interviewed regarding medicinal plants used in veterinary medicine throughout 2001-2010. Based participant observation and open and semi-structured interviews we obtained information on the traditional practices of diagnosis and healing, focusing on the veterinary uses given to plants (part of the plant used, method of preparation and administration. Plants speciemens were collected with the informants and their vernacular and scientific names were registered in a database. Non-parametric statistic was used to evaluate differences in medicinal plant knowledge, use, and valorization by local people. A comparison between traditional veterinary medicine and previous human medicine studies developed in the region was performed by analyzing the percentages of common species and uses, and by considering Sorensen's Similarity Index. Results A total of 127 medicinal uses were registered, corresponding to 70 species of plants belonging to 39 botanic families. Veterinary ethnobotanical knowledge was specialized, restricted, in general, to cattle breeders (mainly men and to a less degree to healers, and was independent of the age of the interviewees. Native plants were mostly used as skin cicatrizants, disinfectants or for treating digestive disorders. Together with a vast repertoire of plant pharmacopoeia, the therapies also involve religious or ritualistic practices and other popular remedies that evidence the influence of traditional Hispanic-European knowledge. Although the traditional veterinary knowledge seems to be similar or else is inlcuded in the local human ethnomedicine, sharing a common group of plants, it has distinct traits originated by a constant assessment of new applications specifically destined to the treatment of animals. Conclusions Veterinary medicine is a fountain of relevant vernacular knowledge, a permanent source for testing new applications with valuable ethnobotanical interest. Knowledge on medicinal applications of native plants will allow future validations and tests for new homeopathic or phytotherapeutic preparations.

  3. Antioxidant activity of the medicinal plant Enicostemma littorale Blume

    Directory of Open Access Journals (Sweden)

    P Abirami

    2011-01-01

    Full Text Available Medicinal plants are the source for wide variety of natural antioxidants. In the study reported here, we have conducted a comparative study between the different parts of the plant Enicostemma littorale. The amount of total phenols and antioxidant enzymes Glutathione-S-Transferase, Superoxide Dismutase, Catalase and Peroxidase activities were evaluated and also the non-enzymatic antioxidants ascorbic acid, α- tocopherol and Glutathione activities were evaluated. The results showed that the antioxidant activities varied greatly among the different plant parts used in this study and some parts are rich in natural antioxidants especially the flowers of E. littorale. These results suggest that Enicostemma littorale have strong antioxidant potential. Further study is necessary for isolation and characterization of antioxidant agents, which can be used to treat various oxidative stress-related diseases.

  4. Pharmacological screening of Malian medicinal plants used against epilepsy and convulsions

    DEFF Research Database (Denmark)

    Pedersen, Mikael E; Vestergaard, Henrik T; Hansen, Suzanne L; Bah, Sekou; Diallo, Drissa; Jäger, Anna

    2009-01-01

    Several medicinal plants are used in Mali to treat epilepsy and convulsions. So far, no studies have investigated the pharmacological effect of these plants.......Several medicinal plants are used in Mali to treat epilepsy and convulsions. So far, no studies have investigated the pharmacological effect of these plants....

  5. From cumulative cultural transmission to evidence-based medicine: evolution of medicinal plant knowledge in Southern Italy.

    Science.gov (United States)

    Leonti, Marco; Staub, Peter O; Cabras, Stefano; Castellanos, Maria Eugenia; Casu, Laura

    2015-01-01

    In Mediterranean cultures written records of medicinal plant use have a long tradition. This written record contributed to building a consensus about what was perceived to be an efficacious pharmacopeia. Passed down through millennia, these scripts have transmitted knowledge about plant uses, with high fidelity, to scholars and laypersons alike. Herbal medicine's importance and the long-standing written record call for a better understanding of the mechanisms influencing the transmission of contemporary medicinal plant knowledge. Here we contextualize herbal medicine within evolutionary medicine and cultural evolution. Cumulative knowledge transmission is approached by estimating the causal effect of two seminal scripts about materia medica written by Dioscorides and Galen, two classical Greco-Roman physicians, on today's medicinal plant use in the Southern Italian regions of Campania, Sardinia, and Sicily. Plant-use combinations are treated as transmissible cultural traits (or "memes"), which in analogy to the biological evolution of genetic traits, are subjected to mutation and selection. Our results suggest that until today ancient scripts have exerted a strong influence on the use of herbal medicine. We conclude that the repeated empirical testing and scientific study of health care claims is guiding and shaping the selection of efficacious treatments and evidence-based herbal medicine. PMID:26483686

  6. Appraisal of medicinal plants used in alternative systems of medicines for microbial contamination, physiochemical parameters and heavy metals

    International Nuclear Information System (INIS)

    The safety of herbal products has become a foremost apprehension in public health with their recognition and worldwide market growth and due in part to the widespread assumption that natural implies harmless. The global market of medicinal plants has been growing at a rate of 7-10% annually; capitalizing on the growing awareness of herbal and aromatic plants globally. The present study was conducted to assess the physiochemical parameters, microbial contamination and presence of heavy metals. The 24 medicinal plants were collected from open market places of various cities of Pakistan and tested by employing WHO and AOAC guidelines. Medicinal plants were found polluted with wide variety of potentially pathogenic bacterias. Microbial count and levels of arsenic and mercury in some plants were found elevated. The percentage (%) of physiochemical parameters i.e., foreign organic matter, total ash, acid insoluble ash, alcohol soluble extract, water soluble extract and moisture count of these medicinal plants were found statistically noteworthy. The nonexistence of quality control values for medicinal plants has been one of the key lacunas. Quality assurance system and WHO's guidelines on good agricultural and collection practices be methodically enforced in the medicinal plants supply chain i.e., cultivation, collection and distribution, although it is tricky task. (author)

  7. Reproduction of the Medicinal Plant Pelargonium sidoides via Somatic Embryogenesis.

    Science.gov (United States)

    Duchow, Stefanie; Blaschek, Wolfgang; Classen, Birgit

    2015-08-01

    The medicinal plant Pelargonium sidoides DC. (Geraniaceae) was traditionally used for the treatment of the common cold and cough in South Africa. Today an aequous-ethanolic root extract from this plant is approved for the treatment of acute bronchitis and is globally marketed also as an immunostimulant. The increasing demand of the plant material for the industrial production indicates the need of new effective methods for the propagation of P. sidoides. Here we report somatic embryogenesis and in vitro plantlet regeneration from somatic cells of inflorescence shoots and petioles of P. sidoides. A one-week cultivation of explants in media containing different concentrations of thidiazuron (1, 2.2, 3, and 4?mg/L) followed by a cultivation period without phytohormones resulted in the induction of somatic embryos within 2-4 weeks. After 2-4 months, the embryos generated roots and could be transferred into a greenhouse, where flower formation took place and the development of seeds occurred with high germination rates. The root umckalin concentration, determined by high-performance thin-layer chromatography, was comparable to that of seed-cultivated plants (100?±?6 vs. 113?±?10?µg umckalin/g dried roots). For the first time, direct somatic embryogenesis has been established as an appropriate cultivation method for P. sidoides plants used as raw material in the pharmaceutical industry. Moreover, genetically identical plants (chemical races) can be easily generated by this procedure. PMID:26287694

  8. Antibacterial Activity of Medicinal Aqueous Plant Extracts against Mycobacterium tuberculosis

    Directory of Open Access Journals (Sweden)

    Muna Mohammed Buzayan

    2012-09-01

    Full Text Available Tuberculosis (TB remains a serious health problem in many regions of the world, and the development of resistance to antibiotics by this microbe created the need for new drugs to replace those which have lost effectiveness. This study assesses the medicinal anti-Mycobacterium tuberculosis properties of natural products obtained from plants collected from Eastern Libya. In this study aqueous extracts of nine different plants were assayed for their Mycobacterium tuberculosis inhibitory activity using the BACTEC MGIT960 susceptibility test method. The aqueous extracts of Ceratonia siliqua L, Helichrysum stoechas (L. Moench and Thymus algeriensis did not show any activity against M. tuberculosis in different concentrations. The aqueous extract of Marrubium vulgare L. from Syria showed high activity against M. tuberculosis. Marrubium alysson L., Marrubium vulgare L., Pistacia lentiscus L, Quercus coccifera L, Thymus capitatus (L. Hoffm. & Link, showed varying degrees of activity against M. tuberculosis. The results of this study show that aqueous extracts from six different medicinal plants have different effects against M. tuberculosis in vitro.

  9. Phytochemical and biological assessment of medicinally important plant ochradenus arabicus

    International Nuclear Information System (INIS)

    Jabal Al-Akhdar (Oman) is one of diverse floral region of Arabian Peninsula. Ochradenus arabicus, is an important medicinal plant to local people of the area. However, little is known about its potential role in biological activities against various emerging ailments. The collected plant samples were extracted with methanol and fractionated into n-hexane (JOAH), ethyl acetate (JOAE), chloroform (JOAC), n-butanol (JOAB) and water (JOAAQ). Various concentrations of these fractions were tested for their antimicrobial, anticancer, antioxidant, antidiabetic, phenolics, flavonoids, allopathic and nutrition quality properties. The results showed that fruits and leaves of O. arabicus have higher levels of carbohydrate, crude fats, fibres, proteins, moisture, ash and energy values. In phytotoxic activities, JOAAQ inhibited the lettuce seed germination and growth. The anticancer activities of fractions showed that JOAE, JOAB and JOAAQ are potent to reduce the cancer cell viability of HT29, HCT116, HepG2 and MCF-7 lines with a concentration of 1000 micro g/ml. JOAB showed a meagre activity of 12% in Glucosidase inhibition assay. The total phenolic and flavonoid contents were significantly higher in JOAE, which also resulted in higher DPPH radical scavenging activity as compared to other fractions and control. JOAE also exhibited higher antibacterial and antifungal activities. The results of current findings suggest that O. arabicus is a potential medicinal plants, which could be subjected to advance column chromatography for lead compounds using a bioassay guided approach. (author)

  10. Heavy metal levels in commonly used traditional medicinal plants

    International Nuclear Information System (INIS)

    In the present study a survey of 24 commonly used medicinal plants of Indian subcontinent origin was carried out to evaluate their levels of heavy metals by electrothermal atomic absorption spectroscopy. The results showed that the highest mean value for Cd (12.06 mu g.g/sup -1/), Cr (24.50 mu g.g/sup -1/), Cu (15.27 mu g.g/sup -1/), Pb (1.30 mu g.g/sup -1/), Fe (885.60 mu g.g/sup -1/), Mn (90.60 mu g.g/sup -1/), Ni (9.99 mu g.g/sup -1/) and Zn (77.15 mu g.g/sup -1/) were found in Lawsonia inermis, Murraya koenigii, Mentha spicata, Beta vulgaris Linn, Mentha spicata, Lagenaria sicerana standl, Lawsonia inermis, Emblica officinalis, respectively. The mean and maximum levels of Cd in plant samples were found higher than the recommended values of the Joint Expert Committee on Food Additives of the Food and Agriculture Organization of the United Nations and the World Health Organization and may constitute a health hazard for consumers. All other heavy metals in medicinal plants were found below the recommended tolerable limits. (author)

  11. Review on Medicinal Plants used by Local Community of Jodhpur District of Thar Desert

    OpenAIRE

    B. P. Nagori; Sasmal, D.; Manoj Goyal

    2011-01-01

    The traditional uses of medicinal plants in healthcare practices are providing clues to new areas of research; hence its importance is now well recognized. However, information on the uses of indigenous plants for medicine is not well documented from many rural areas of Rajasthan. Questionnaire surveys, participatory observations and field visits were planned to elicit information on the medicinal plants used by local community of Jodhpur district of Thar desert. The use of 21 plants distribu...

  12. Antimutagenic Effect of Medicinal Plants Achillea millefolium and Bauhinia forficata In Vivo

    OpenAIRE

    Elisângela Düsman; Igor Vivian de Almeida; Ana Carolina Coelho; Thiago José Balbi; Lilian Tatiani Düsman Tonin; Veronica Elisa Pimenta Vicentini

    2013-01-01

    The investigation of traditionally used medicinal plants is valuable both as a source of potential chemotherapeutic drugs and as a measure of safety for the continued use of these medicinal plants. Achillea millefolium L. (AM) is an ancient remedial herb native to Europe that is used to treat wounds, gastrointestinal and hepatobiliary disorders, inflammation, headaches, and pain. Bauhinia forficata Link (BF), an Asiatic plant, is one of the most commonly used plants in folk medicine against d...

  13. An ethnobotanical survey of medicinal plants used in the eastern highlands of Papua New Guinea

    OpenAIRE

    Jorim Ronald Y; Korape Seva; Legu Wauwa; Koch Michael; Barrows Louis R; Matainaho Teatulohi K; Rai Prem P

    2012-01-01

    Abstract Background The Eastern Highlands area of Papua New Guinea (PNG) has a rich tradition of medicinal plant use. However, rapid modernization is resulting in the loss of independent language traditions and consequently a loss of individuals knowledgeable in medicinal plant use. This report represents a program to document and preserve traditional knowledge concerning medicinal plant use in PNG. This report documents and compares traditional plant use in the Eastern Highlands districts of...

  14. Ethnopharmacological Survey of Medicinal Plants in Malaysia, the Kangkar Pulai Region

    OpenAIRE

    T. Aburjai; M.R.A. Kadir; Sultana, N.; A. Alsarhan

    2012-01-01

    The medicinal plants play an important role in rural health care system throughout the world in remedying and preventing various kinds of diseases. This study documented the use of plants as traditional herbal medicine in the Kangkar Pulai region Johor, Malaysia. It also identified the homogeneity of informant knowledge on medicinal plants suitable for different ailments and types of plants most favored for the treatment of each ailment in the study. The information was gathered through semi-...

  15. A SURVEY OF IMPORTANT INDIGENOUS MEDICINAL PLANTS OF DISTRICT BHIMBER AZAD JAMMU & KASHMIR, PAKISTAN

    OpenAIRE

    Nazar Hussain; S.A. Majid; M. Altaf Hussain; M. Saleem Abbasi

    2013-01-01

    A survey of medicinal plants was carried out about the traditional knowledge of rural people of District Bhimber and its allied areas. It was established that 96 plant species belonging to 49 families are currently used by common people and traditional plant medicines practitioner. Most medicinal plants grow in the wild (75%), while others are cultivated (25%) with predominant share of herbs (55%), trees (27%) and shrubs (17%). The frequently used species were Justicia adhatoda, Azadirachta i...

  16. Medicinal Plants Used as Antitumor Agents in Brazil: An Ethnobotanical Approach

    OpenAIRE

    Silene Carneiro do Nascimento; Ulysses Paulino de Albuquerque; Elba Lúcia Cavalcanti de Amorim; Ariane Gaspar Santos; Joabe Gomes Melo

    2011-01-01

    We describe the medicinal plants that have been reported to be antitumor agents and that have been used in ethnobotanic research in Brazil to answer the following questions: what is the abundance of plants reported to be antitumor in Brazil? Have the plant species used for tumor treatment in traditional Brazilian medicine been sufficiently examined scientifically? Our analysis included papers published between 1980 and 2008. A total of 84 medicinal plant species were reported to be used for c...

  17. Hypolipidimic effect of some medicinal plants on diabetic rats

    OpenAIRE

    Eman G.E.Helal * and Mohamed M. A. Shahat

    2006-01-01

    Our aim was to evaluate the hypolipidimic effect of aqueous extract of a famous mixture used in Saudi Arabia folk medicine that consists of Nigella sativa, Commiphora myrrha, Boswellia carterii Birdw, Ferule assa-foetida and Aloe vera and also the extract of each plant alone on alloxan induced diabetic rats. Material and Methods :-The present study was carried out on 80 adult male albino rats (120 ± 20 g.b.wt. ), the rats were divided randomly into 8 groups, the first group served as control ...

  18. SYNERGISTIC EFFET OF INDIGENOUS MEDICINAL PLANT EXTRACTS ON PSORIASIS

    Directory of Open Access Journals (Sweden)

    anusha swarna

    2013-03-01

    Full Text Available AbstractThe present paper deals with evaluation of synergistic effect of two medicinal plants, Ponamia pinnata Linn and Psoralea corylifolia Linn. Extraction was carried out with soxhlet apparatus using the solvent ethanol. The anti-psoriatic activity was done by Induction of psoriasiform changes in guinea pig by propranolol method and Rat UV B rays Photo dermatitis model for psoriasis. Antimicrobial activity by plate hole diffusion method. Ethanolic extract exhibited significant effect of anti-psoriatic and antimicrobial activity. Both the extracts show synergistic effect on both psoriasis and antimicrobial studies when compared with the individual extracts. 

  19. Concentration of some radionuclides in some popular sudanese medicinal plants

    International Nuclear Information System (INIS)

    In this study was measured concentration of naturally occurring radionuclides 238U, 232Th and 40K in samples of sudanese medicinal plants. The radionuclide activity concentrations in samples analyzed ranged from 4.09 to 41.07 Bq kg-1 for 238Th and from 353.14 to 2270.21 Bq kg-1 for 40k. No trace of artificial radionuclide was determined in all the samples. The effective dose due to the presence of these radionuclides was estimated and found to be 0.524 mSv/year which is well below the permissible levels. (Author)

  20. The role and place of medicinal plants in the strategies for disease prevention.

    Science.gov (United States)

    Sofowora, Abayomi; Ogunbodede, Eyitope; Onayade, Adedeji

    2013-01-01

    Medicinal plants have been used in healthcare since time immemorial. Studies have been carried out globally to verify their efficacy and some of the findings have led to the production of plant-based medicines. The global market value of medicinal plant products exceeds $100 billion per annum. This paper discusses the role, contributions and usefulness of medicinal plants in tackling the diseases of public health importance, with particular emphasis on the current strategic approaches to disease prevention. A comparison is drawn between the 'whole population' and 'high-risk' strategies. The usefulness of the common-factor approach as a method of engaging other health promoters in propagating the ideals of medicinal plants is highlighted. The place of medicinal plants in preventing common diseases is further examined under the five core principles of the Primary Health Care (PHC) approach. Medicinal plants play vital roles in disease prevention and their promotion and use fit into all existing prevention strategies. However, conscious efforts need to be made to properly identify, recognise and position medicinal plants in the design and implementation of these strategies. These approaches present interesting and emerging perspectives in the field of medicinal plants. Recommendations are proposed for strategising the future role and place for medicinal plants in disease prevention. PMID:24311829

  1. Antimicrobial and toxicological activities of five medicinal plant species from Cameroon Traditional Medicine

    Directory of Open Access Journals (Sweden)

    Njouendou Abdel J

    2011-08-01

    Full Text Available Abstract Background Infectious diseases caused by multiresistant microbial strains are on the increase. Fighting these diseases with natural products may be more efficacious. The aim of this study was to investigate the in vitro antimicrobial activity of methanolic, ethylacetate (EtOAc and hexanic fractions of five Cameroonian medicinal plants (Piptadeniastum africana, Cissus aralioides, Hileria latifolia, Phyllanthus muellerianus and Gladiolus gregasius against 10 pathogenic microorganisms of the urogenital and gastrointestinal tracts. Methods The fractions were screened for their chemical composition and in vivo acute toxicity was carried out on the most active extracts in order to assess their inhibitory selectivity. The agar well-diffusion and the micro dilution methods were used for the determination of the inhibition diameters (ID and Minimum inhibitory concentrations (MIC respectively on 8 bacterial species including two Gram positive species (Staphylococcus aureus, Enterococcus faecalis, and six Gram negative (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Shigella flexneri, Salmonella typhi and two fungal isolates (Candida albicans, Candida krusei. The chemical composition was done according to Harbone (1976, the acute toxicity evaluation according to WHO protocol and the hepatic as well as serum parameters measured to assess liver and kidney functions. Results The chemical components of each plant's extract varied according to the solvent used, and they were found to contain alkaloids, flavonoids, polyphenols, triterpens, sterols, tannins, coumarins, glycosides, cardiac glycosides and reducing sugars. The methanolic and ethylacetate extracts of Phyllanthus muellerianus and Piptadeniastum africana presented the highest antimicrobial activities against all tested microorganisms with ID varying from 8 to 26 mm and MIC from 2.5 to 0.31 mg/ml. The in vivo acute toxicity study carried out on the methanolic extracts of Phyllanthus muellerianus and Piptadeniastrum africana indicated that these two plants were not toxic. At the dose of 4 g/kg body weight, kidney and liver function tests indicated that these two medicinal plants induced no adverse effect on these organs. Conclusion These results showed that, all these plant's extracts can be used as antimicrobial phytomedicines which can be therapeutically used against infections caused by multiresistant agents. Phyllanthus muellerianus, Piptadeniastum africana, antimicrobial, acute toxicity, kidney and liver function tests, Cameroon Traditional Medicine

  2. Anti-Candida activity of Brazilian medicinal plants.

    Science.gov (United States)

    Duarte, Marta Cristina Teixeira; Figueira, Glyn Mara; Sartoratto, Adilson; Rehder, Vera Lúcia Garcia; Delarmelina, Camila

    2005-02-28

    Essential oils and ethanolic extracts from the leaves and/or roots of 35 medicinal plants commonly used in Brazil were screened for anti-Candida albicans activity. The oils were obtained by water-distillation using a Clevenger-type system. Essential oils from 13 plants showed anti-Candida activity, including Aloysia triphylla, Anthemis nobilis, Cymbopogon martini, Cymbopogon winterianus, Cyperus articulatus, Cyperus rotundus, Lippia alba, Mentha arvensis, Mikania glomerata, Mentha piperita, Mentha sp., Stachys byzantina, and Solidago chilensis. The ethanol extract was not effective at any of the concentrations tested. Chemical analyses showed the presence of compounds with known antimicrobial activity, including 1,8-cineole, geranial, germacrene-D, limonene, linalool, and menthol. PMID:15707770

  3. MEDICINAL PROPERTIES OF MANGROVE PLANTS – AN OVERVIEW

    Directory of Open Access Journals (Sweden)

    Revathi P*, T Jeyaseelan Senthinath, P Thirumalaikolundusubramanian and N Prabhu

    2013-12-01

    Full Text Available Perhaps the most important role of mangroves is that they protect vulnerable coastlines from wave action because they hold the soil together and prevent coastal erosion. Mangroves shield inland areas during storms and minimize damage. For example, learning from the 2005 tsunami in Asia, there were no deaths in the areas which had mangrove forests, compared to those areas without, which suffered massive causalities. Many species in the mangrove forest have medicinal value and it has been proved that these plants are antiviral and antibacterial in nature. Community participation is must to enhance mangrove habitats. Plant species in this ecosystem like Avicennia Marina, Sesuvium Portulacastrum and Suaeda Monoica have chemical properties that can kill vectors namely Anopheles, Culex and Aedes, which cause diseases such as malaria, filariasis and dengue fever.

  4. Antimicrobial Activity of Some Medicinal Plants from Malaysia

    Directory of Open Access Journals (Sweden)

    Koshy Philip

    2009-01-01

    Full Text Available Problem statement: About 32 extracts from eight selected medicinal plants, namely Pereskia bleo, Pereskia grandifolia, Curcuma aeruginosa Roxb., Curcuma zedoria, Curcuma mangga, Curcuma inodora aff. Blatter, Zingiber officinale var. officinale (jahe gajah and Zingiber officinale var. rubrum (jahe emprit used by Malaysia traditional health care systems were screened for their antimicrobial activity against both Gram-positive bacteria and Gram-negative bacteria using agar disc diffusion assay. Approach: The efficacy of the extracts was compared to the commercially prepared antibiotic diffusion discs. Results: No inhibition was observed with the water fractions. Conclusion/Recommendations: None of the plants tested showed inhibition against Escherichia coli. Curcuma mangga showed some remarked inhibition against the bacteria used in this study.

  5. [Severe poisoning by plants used for traditional medicine in Mayotte].

    Science.gov (United States)

    Durasnel, P; Vanhuffel, L; Blondé, R; Lion, F; Galas, T; Mousset-Hovaere, M; Balaÿ, I; Viscardi, G; Valyi, L

    2014-12-01

    The authors describe three cases of severe accidental poisoning by plants used as part of a traditional treatment in Mayotte. The established, or suspected, toxicity of Thevetia peruviana (Yellow oleander), Cinchona pubescens (Red quinine-tree), Melia azaderach (Persian lilac, also called china berry) and Azadirachta indica (Neem), is discussed. The clinical presentation is cardiac (atrioventricular block) and well known for Thevetia and Cinchona intoxications. Neurological signs and multi-organ failure are found for Azadirachta and Melia. The identification of the plants is never easy, nor is the evidence of their accountability. In the three cases reported, no other cause than the traditional treatment has been found to explain the clinical presentation. The outcome was favorable in all cases. The authors emphasize the difficulties to investigate these accidents, the poor medical knowledge of these practices in tropical areas, and in Mayotte particularly. The need for cooperation with local botanists, familiar with traditional medicine, is also underlined. PMID:25301110

  6. As monografias sobre plantas medicinais / The medicinal plants monographs

    Scientific Electronic Library Online (English)

    Valdir F., Veiga Junior; João Carlos P., Mello.

    2008-09-01

    Full Text Available As monografias sobre plantas medicinais ou drogas vegetais contêm informações para atender não somente aos órgãos de regulamentação, mas também às empresas industriais farmacêuticas e farmácias, e mesmo ao público consumidor. Este artigo revê as monografias da Comissão E, do American Botanical Counc [...] il, ESCOP, PDR e da Organização Mundial de Saúde em suas origens, objetivos e formatos. Duas publicações recentemente organizadas pela FIOCRUZ do Rio de Janeiro e as contribuições da Farmacopéia Brasileira também são avaliadas. Abstract in english The medicinal plants monographs are very important information collections about some of the most consumed plants all over the world that attend not only the regulatory agencies but also pharmaceutical industries and the general consumer. This manuscript reviews the origins, objectives and formats o [...] f the most important monographs, like Commission E, American Botanical Council, ESCOP, PDR and WHO. Two recently published Brazilian experiences organized by FIOCRUZ and the contributions from Brazilian Pharmacopoeia are also evaluated.

  7. In vitro antioxidant properties and characterization in nutrients and phytochemicals of six medicinal plants from the Portuguese folk medicine

    OpenAIRE

    Barros, Lillian; Oliveira, Sónia; Carvalho, Ana Maria; Ferreira, Isabel C. F. R.

    2010-01-01

    Traditional ethnomedical use of plants is recognized as an important potential source of compounds used in mainstream medicine. Herein, the in vitro antioxidant properties, nutrients and phytochemical composition of six medicinal plants widely used in the north-eastern Portuguese region were evaluated. The antioxidant activity was screened through: radical scavenging effects, reducing power, and inhibition of lipid peroxidation in brain homogenates. Nutrients and phytochemical characterizatio...

  8. Vibriocidal activity of certain medicinal plants used in Indian folklore medicine by tribals of Mahakoshal region of central India

    OpenAIRE

    Sharma Anjana; Patel Virendra; Chaturvedi Animesh

    2009-01-01

    Objectives: Screening of the medicinal plants and determination of minimum inhibitory concentration (MIC) against Vibrio cholerae and Vibrio parahaemolyticus. Materials and Methods: A simple in vitro screening assay was employed for the standard strain of Vibrio cholerae, 12 isolates of Vibrio cholerae non-O1, and Vibrio parahaemolyticus. Aqueous and organic solvent extracts of different parts of the plants were investigated by using the disk diffusion method. Extracts from 16 medicinal pl...

  9. Medicinal plant activity on Helicobacter pylori related diseases.

    Science.gov (United States)

    Wang, Yuan-Chuen

    2014-08-14

    More than 50% of the world population is infected with Helicobacter pylori (H. pylori). The bacterium highly links to peptic ulcer diseases and duodenal ulcer, which was classified as a group?I?carcinogen in 1994 by the WHO. The pathogenesis of H. pylori is contributed by its virulence factors including urease, flagella, vacuolating cytotoxin A (VacA), cytotoxin-associated gene antigen (Cag A), and others. Of those virulence factors, VacA and CagA play the key roles. Infection with H. pylori vacA-positive strains can lead to vacuolation and apoptosis, whereas infection with cagA-positive strains might result in severe gastric inflammation and gastric cancer. Numerous medicinal plants have been reported for their anti-H. pylori activity, and the relevant active compounds including polyphenols, flavonoids, quinones, coumarins, terpenoids, and alkaloids have been studied. The anti-H. pylori action mechanisms, including inhibition of enzymatic (urease, DNA gyrase, dihydrofolate reductase, N-acetyltransferase, and myeloperoxidase) and adhesive activities, high redox potential, and hydrophilic/hydrophobic natures of compounds, have also been discussed in detail. H. pylori-induced gastric inflammation may progress to superficial gastritis, atrophic gastritis, and finally gastric cancer. Many natural products have anti-H. pylori-induced inflammation activity and the relevant mechanisms include suppression of nuclear factor-?B and mitogen-activated protein kinase pathway activation and inhibition of oxidative stress. Anti-H. pylori induced gastric inflammatory effects of plant products, including quercetin, apigenin, carotenoids-rich algae, tea product, garlic extract, apple peel polyphenol, and finger-root extract, have been documented. In conclusion, many medicinal plant products possess anti-H. pylori activity as well as an anti-H. pylori-induced gastric inflammatory effect. Those plant products have showed great potential as pharmaceutical candidates for H. pylori eradication and H. pylori induced related gastric disease prevention. PMID:25132753

  10. An Ethnopharmacological Study of Medicinal Plants in New South Wales

    Directory of Open Access Journals (Sweden)

    D. Randall

    2005-10-01

    Full Text Available The Australian Aboriginal people have used plants as medicine and food for thousands of years, however, this traditional knowledge is documented only to a limited extent, and is in danger of being lost. The Indigenous Bioresources Research Group (IBRG aims to help Australian Aboriginal communities to preserve their customary medicinal knowledge, and to provide information that can be used for their cultural or educational purposes, as well as for scientific advancement. This work is undertaken in close collaboration with Australian Aboriginal communities in New South Wales. The project is multidisciplinary, combining an ethnobotanical and an ethnopharmacological approach, which includes biological and chemical investigations, as well as developing best practices for protecting traditional knowledge. This paper describes the general strategy of the project as well as methods used in the ethnopharmacological study. Ethnobotanical databases are set up for each participating community. Plant material is collected, extracted, and active compounds are isolated using a bioassay-guided fractionation approach. All extracts and compounds are tested for biological activity in antimicrobial assays (disc diffusion, resazurin, fluorescein diacetate, neurological assays or anti-inflammatory assays, depending on their traditional use.

  11. Screening of estrogenic and antiestrogenic activities from medicinal plants.

    Science.gov (United States)

    Kim, In Gyu; Kang, Se Chan; Kim, Kug Chan; Choung, Eui Su; Zee, Ok Pyo

    2008-01-01

    The medicinal plant extracts commercially used in Asia were screened for their estrogenic and antiestrogenic activities in a recombinant yeast system featuring both a human estrogen receptor (ER) expression plasmid and a reporter plasmid. Pueraria lobata (flower) had the highest estrogenic relative potency (RP, 7.75×10(-3); RP of 17?-estradiol=1), followed by Amomum xanthioides (1.25×10(-3)). Next potent were a group consisting of Glycyrrhiza uralensis, Zingiber officinale, Rheum undulatum, Curcuma aromatica, Eriobotrya japonica, Sophora flavescens, Anemarrhena asphodeloides, Polygonum multiflorum, and Pueraria lobata (root) (ranging from 9.5×10(-4) to 1.0×10(-4)). Least potent were Prunus persica, Lycoppus lucidus, and Adenophora stricta (ranging from 9.0×10(-5) to 8.0×10(-5)). The extracts exerting antiestrogenic effects, Cinnamomum cassia and Prunus persica, had relative potencies of 1.14×10(-3) and 7.4×10(-4), respectively (RP of tamoxifen=1). The solvent fractions from selected estrogenic or antiestrogenic herbs had higher estrogenic relative potencies, with their RP ranging from 9.3×10(-1) to 2.7×10(-4) and from 8.2×10(-1) to 9.1×10(-3), respectively. These results support previous reports on the efficacy of Oriental medicinal plants used or not used as phytoestrogens for hormone replacement therapy. PMID:21783839

  12. Protective Effect against Oxidative Stress in Medicinal Plant Extracts

    International Nuclear Information System (INIS)

    Protective effect of medicinal plant extracts against oxidative stress were screened in this study. Methanol extracts from 48 medicinal plants, which were reported to have antioxidative or anti-inflammatory effect were prepared and screened for their protective activity against chemically-induced and radiation-induced oxidative stress by using MTT assay. Thirty three samples showed protective activity against chemically-induced oxidative stress in various extent. Among those samples, extract of Glycyrrhiza uralensis revealed the strongest activity (25.9% at 100 ?g/ml) with relatively lower cytotoxicity. Seven other samples showed higher than 20% protection at 100 ?g/ml. These samples were tested for protection activity against radiation-induced oxidative stress. Methanol extract of Alpina officinarum showed the highest activity (17.8% at 20 ?g/ml). Five fractions were prepared from the each 10 methanol extracts which showed high protective activity against oxidative stress. Among those fraction samples butanol fractions of Areca catechu var. dulcissima and Spirodela polyrrhiza showed the highest protective activities (78.8% and 77.2%, respectively, at 20 ?g/ml)

  13. Protective Effect against Oxidative Stress in Medicinal Plant Extracts

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jeong Hee; Lee, Eun Ju; Shin, Dong O; Hong, Sung Eun [Kyunghee Univ., Seoul (Korea, Republic of); Kim, Jin Kyu [KAERI, Daejeon (Korea, Republic of)

    2000-03-15

    Protective effect of medicinal plant extracts against oxidative stress were screened in this study. Methanol extracts from 48 medicinal plants, which were reported to have antioxidative or anti-inflammatory effect were prepared and screened for their protective activity against chemically-induced and radiation-induced oxidative stress by using MTT assay. Thirty three samples showed protective activity against chemically-induced oxidative stress in various extent. Among those samples, extract of Glycyrrhiza uralensis revealed the strongest activity (25.9% at 100 {mu}g/ml) with relatively lower cytotoxicity. Seven other samples showed higher than 20% protection at 100 {mu}g/ml. These samples were tested for protection activity against radiation-induced oxidative stress. Methanol extract of Alpina officinarum showed the highest activity (17.8% at 20 {mu}g/ml). Five fractions were prepared from the each 10 methanol extracts which showed high protective activity against oxidative stress. Among those fraction samples butanol fractions of Areca catechu var. dulcissima and Spirodela polyrrhiza showed the highest protective activities (78.8% and 77.2%, respectively, at 20 {mu}g/ml)

  14. A comparative study on medicinal plants used in Akha's traditional medicine in China and Thailand, cultural coherence or ecological divergence?

    DEFF Research Database (Denmark)

    Inta, A.; Shengji, P.; Balslev, Henrik; Wangpakapattanawong, P.; Trisonthi, C.

    2008-01-01

    Aim of the study : The survey aims to study the effect of geographic separation of ethnic groups on local knowledge of medicinal plants used by Akha people in Thailand and China, who were separated 100-120 years ago, to see how different the two geographically distinct but culturally similar groups...... Thailand. Otherwise the use patterns were quite similar with respect to which plant families and plant growth forms were used and also in terms of in which habitats the Akha found their medicinal plants. Conclusions : The moving to a different site has forced the Akha to find a new set of species, but that...

  15. A SHORT REVIEW ON UN-EXPLORED MEDICINAL PLANT: ECBOLIUM VIRIDIE

    Directory of Open Access Journals (Sweden)

    A. Elumalai

    2011-05-01

    Full Text Available Medicinal plants are the nature’s gift to human being to make disease free healthy life. It plays a vital role to preserve our health. In our country more than 2000 medicinal plants are recognized. Ecbolium viridie (Acanthaceae is one of the important medicinal plant in India and Malaysia. Some of its medicinal uses have been mentioned in traditional system of medicine such as ayurveda, siddha and unani. This review attempts to encompass the available literature of Ecbolium viridie with respect to its traditional uses and summary of its pharmacological activities.

  16. Free Radical Scavenging Activity of Some Nigerian Medicinal Plant Extracts

    Directory of Open Access Journals (Sweden)

    M.O. Sofidiya

    2006-01-01

    Full Text Available The present research evaluates the DPPH radical scavenging, total antioxidant activities, reducing power and total contents of phenolic compounds in methanolic leaf extracts of five Nigerian medicinal plants (Dalbergia saxatilis Hook.f. (Papilionacae, Ekebergia senegalensis A.Juss.(Meliaceae, Hymenocardia acida Tul. (Hymenocardiaceae, Icacina tricantha Oliv. (Icacinaceae and Salacia pallescens Oliv.(Celastraceae. Total phenols were analysed according to the Folin-Ciocalteu method. Each sample under assay condition, showed a dose-dependent effect both on free radical scavenging 1,1-diphenyl-2-picrylhydrazyl radical (DPPH and also on Fe3+ reducing power. The antioxidant activity of the plant extracts with the DPPH radical scavenging and reducing power method, were in the order Hymenocardia> Ekebergia> Salacia> Icacina> Dalbergia. H. acida and E. senegalensis possess very high radical scavenging activity in both assays. Potency of H. acida extract was of the same magnitude as that of reference ?-tocopherol. Total phenols in all the samples expressed as GAE (Gallic Acid Equivalent varied from 1.83 to 15.47mg g-1 of dry plant material. Total antioxidant activities correlated with total phenols (R2 = 0.6640 an indication that 66% of the antioxidant capacity of these extracts results from contribution of phenolic compounds. A linear positive relationship existed between the reducing power and total phenolics of the tested plant extracts (R2 = 0.9564.

  17. A Review on Medicinal Plants with Anti-Ulcer Activity

    Directory of Open Access Journals (Sweden)

    Shaikh A. M

    2013-05-01

    Full Text Available A peptic ulcer is erosion in a segment of the gastro intestinal mucosa. It may typically in the stomach (gastric ulcer or first few centimeters of duodenum (duodenal ulcer that penetrates through the muscularis mucosae. Contrary to popular belief, ulcer is not only caused by spicy food but also most commonly due to an infection of Helicobacter Pylori and long term use of medications. Standard treatment is a combination of drugs including antibiotics and a proton pump inhibitors. Literature suggests that number of synthetic drugs are used in the management of peptic ulcers but elicit several adverse effects. Therefore Indian herbal plants stand out as being exceptional for its ethnic, ethobotanical and ethno-pharmaceutical use. In this review attempts have been made to know about some plants which may be used in treatment or prevention of peptic ulcers. Various plants like Excoecaria agallocha, Mentha arvensis, Utleria salicifolia, Emblica officinalis etc. proved active in antiulcer therapy. This combination of traditional and modern knowledge can produced better antiulcer drugs with fewer side effects. The medicinal plants are available in India and other countries, recent technologies advances have renewal interest in natural product in drug discovery.

  18. Evaluation of three medicinal plants for anti-microbial activity.

    Science.gov (United States)

    Pratap, Gowd M J S; Manoj, Kumar M G; Sai, Shankar A J; Sujatha, B; Sreedevi, E

    2012-07-01

    Herbal remedies have a long history of use for gum and tooth problems such as dental caries. The present microbiological study was carried out to evaluate the antimicrobial efficacy of three medicinal plants (Terminalia chebula Retz., Clitoria ternatea Linn., and Wedelia chinensis (Osbeck.) Merr.) on three pathogenic microorganisms in the oral cavity (Streptococcus mutans, Lactobacillus casei, and Staphylococcus aureus). Aqueous extract concentrations (5%, 10%, 25%, and 50%) were prepared from the fruits of Terminalia chebula, flowers of Clitoria ternatea, and leaves of Wedelia chinensis. The antimicrobial efficacy of the aqueous extract concentrations of each plant was tested using agar well diffusion method and the size of the inhibition zone was measured in millimeters. The results obtained showed that the diameter of zone of inhibition increased with increase in concentration of extract and the antimicrobial efficacy of the aqueous extracts of the three plants was observed in the increasing order - Wedelia chinensis Clitoria ternatea < Terminalia chebula. It can be concluded that the tested extracts of all the three plants were effective against dental caries causing bacteria. PMID:23723653

  19. Interacción entre fármacos y plantas medicinales / Interaction between medicines and medicinal plants

    Scientific Electronic Library Online (English)

    J.C., Tres.

    2006-08-01

    Full Text Available En los últimos años, el consumo de plantas medicinales ha experimentado un notable incremento en la sociedad española. Esto ha podido ser debido a que en algunos casos, se ha demostrado su eficacia en el tratamiento de determinadas patologías y a la percepción, errónea, de la inocuidad de estos prod [...] uctos. Las plantas medicinales se comportan como verdaderos fármacos ya que las sustancias químicas que las componen pueden tener una actividad biológica en humanos. Por esta razón, la administración conjunta con "fármacos convencionales" puede producir variaciones en la magnitud de su efecto. Este tipo de interacciones, al igual que las producidas entre dos o más fármacos pueden producirse por mecanismos farmacocinéticos, si afectan a procesos de absorción, distribución, metabolismo y excreción o farmacodinámicos, si afectan al resultado de su acción farmacológica. En la literatura médica son escasos los artículos y notificaciones de casos sobre los efectos adversos e interacciones que afectan a las plantas medicinales, lo que probablemente refleja una infranotificación de estos fenómenos. Si a esto añadimos la falta de datos experimentales y de estudios controlados, la percepción de su prevalencia es difícil o casi imposible. Este trabajo expone, ordenados según se explica más adelante, los hallazgos de una exhaustiva revisión de la literatura médica con el fin de que el lector conozca su existencia, sin entrar en otras consideraciones, como por ejemplo el grado de evidencia, que serán sujeto de próximos trabajos. Abstract in english In recent years there has been a notable increase in the consumption of medicinal plants in Spanish society. This might be due to the fact that in some cases they have shown themselves to be efficient in treating certain pathologies and to the erroneous perception that these products are innocuous. [...] Medicinal plants behave as authentic medicines since the chemical substances of which they are formed can have a biological activity in humans. For this reason, their joint administration with "conventional medicines" can produce variations in the magnitude of the effect. This type of interaction, just like those produced between two or more medicines, can produce pharmacokinetic mechanisms if they affect the processes of absorption, distribution, metabolism and excretion, or pharmacodynamic mechanisms if they affect the result of the pharmacological action. In the medical literature there are few articles and notifications of cases concerning the adverse effects and interactions that affect medicinal plants, which probably reflects an under-notification of these phenomena. If we add to this the lack of experimental data and controlled studies, perception of their prevalence is difficult or nearly impossible. This article sets out, in an order that will be explained later, the findings of an exhaustive review of the medical literature with the aim of making its existence known to the reader, without going into other considerations, such as the degree of evidence for example, which will be the subject of forthcoming articles.

  20. Interacción entre fármacos y plantas medicinales Interaction between medicines and medicinal plants

    Directory of Open Access Journals (Sweden)

    J.C. Tres

    2006-08-01

    Full Text Available En los últimos años, el consumo de plantas medicinales ha experimentado un notable incremento en la sociedad española. Esto ha podido ser debido a que en algunos casos, se ha demostrado su eficacia en el tratamiento de determinadas patologías y a la percepción, errónea, de la inocuidad de estos productos. Las plantas medicinales se comportan como verdaderos fármacos ya que las sustancias químicas que las componen pueden tener una actividad biológica en humanos. Por esta razón, la administración conjunta con "fármacos convencionales" puede producir variaciones en la magnitud de su efecto. Este tipo de interacciones, al igual que las producidas entre dos o más fármacos pueden producirse por mecanismos farmacocinéticos, si afectan a procesos de absorción, distribución, metabolismo y excreción o farmacodinámicos, si afectan al resultado de su acción farmacológica. En la literatura médica son escasos los artículos y notificaciones de casos sobre los efectos adversos e interacciones que afectan a las plantas medicinales, lo que probablemente refleja una infranotificación de estos fenómenos. Si a esto añadimos la falta de datos experimentales y de estudios controlados, la percepción de su prevalencia es difícil o casi imposible. Este trabajo expone, ordenados según se explica más adelante, los hallazgos de una exhaustiva revisión de la literatura médica con el fin de que el lector conozca su existencia, sin entrar en otras consideraciones, como por ejemplo el grado de evidencia, que serán sujeto de próximos trabajos.In recent years there has been a notable increase in the consumption of medicinal plants in Spanish society. This might be due to the fact that in some cases they have shown themselves to be efficient in treating certain pathologies and to the erroneous perception that these products are innocuous. Medicinal plants behave as authentic medicines since the chemical substances of which they are formed can have a biological activity in humans. For this reason, their joint administration with "conventional medicines" can produce variations in the magnitude of the effect. This type of interaction, just like those produced between two or more medicines, can produce pharmacokinetic mechanisms if they affect the processes of absorption, distribution, metabolism and excretion, or pharmacodynamic mechanisms if they affect the result of the pharmacological action. In the medical literature there are few articles and notifications of cases concerning the adverse effects and interactions that affect medicinal plants, which probably reflects an under-notification of these phenomena. If we add to this the lack of experimental data and controlled studies, perception of their prevalence is difficult or nearly impossible. This article sets out, in an order that will be explained later, the findings of an exhaustive review of the medical literature with the aim of making its existence known to the reader, without going into other considerations, such as the degree of evidence for example, which will be the subject of forthcoming articles.

  1. Chemical constituents of selected Sudanese medicinal and aromatic plants

    International Nuclear Information System (INIS)

    Sudanese medicinal and aromatic plants (Alternanthra repens, Ambrosia maritima, Citrus paradisi, Croton zambesicus, Lepidium sativum, Morettia phillaena, Nauclea latifolia, Plectranthus barbatus, Pluchea dioscorides, and Sphaeranthus suaveolens) were analyzed for their chemical composition, mineral contents and secondary constituents. The concentration of manganese, copper, iron, nickel, lead, zinc and potassium in plant samples was performed using x-ray fluorescence spectrometry. The trace elements found in the smallest amount of the investigated plant species are lead, nickel and copper, while high concentration was detected for potassium, iron and manganese. Mn was accumulated with high level in Alternanthra repens species. Potassium was abundant in S. suaveolens and Ambrosia maritima. The values of concentration obtained for all studied elements were compared with published values of reference material, trace elements in Hay (powder) by International Atomic Energy Agency. Phyto chemical analysis of investigated plants was performed for constituents: Flavonoids, saponins, tannins, alkaloids, amino acids and sugars. The methanolic extracts of P.barbatus, C.paradisi, A.repens, N.latifolia, L. sativum and C. zambesicus are found to contain alkaloids. Results of TLC analysis were shown as Rf values for saponins, bitter principles, essential oils, flavonoids and alkaloids. Quantification of flavonoids and tannins showed that flavonoid content was highest in case of Alternanthera repens and Sphaeranthus suavertens, whereas the highest tannin content was in case of Nauclea latifolia and Sphaearanthus suavertens. The results suggest that the user of traditional Sudanese crude drugs should be warned of potential danger of heavy metal poisoning because their concentrations seem to be higher than maximum values allowed by health agencies in several countries. This study has provided some biochemical basis for the ethno medical use of extracts from different candidate plant species in the treatment and prevention of diseases. As rich source of phytochemicals and minerals these plants can be a potential source of useful drugs, and also used as bio indicators to follow changes in an environmental pollution.(Author)

  2. Cytotoxic activity screening of Bangladeshi medicinal plant extracts.

    Science.gov (United States)

    Akter, Raushanara; Uddin, Shaikh J; Grice, I Darren; Tiralongo, Evelin

    2014-01-01

    The cytotoxic activity of 23 crude methanol extracts from 19 Bangladeshi medicinal plants was investigated against healthy mouse fibroblasts (NIH3T3), healthy monkey kidney (VERO) and four human cancer cell lines (gastric, AGS; colon, HT-29; and breast, MCF-7 and MDA-MB-231) using MTT assay. High cytotoxicity across all cell lines tested was exhibited by Aegiceras corniculatum (fruit) and Hymenodictyon excelsum (bark) extracts (IC50 values ranging from 0.0005 to 0.9980 and 0.08 to 0.44 mg/mL, respectively). Fourteen extracts from 11 plant species, namely Clitoria ternatea (flower and leaf), Dillenia indica (leaf), Diospyros peregrina (leaf), Dipterocarpus turbinatus (bark and leaf), Ecbolium viride (leaf), Glinus oppositifolius (whole plant), Gnaphalium luteoalbum (leaf), Jasminum sambac (leaf), Lannea coromandelica (bark and leaf), Mussaenda glabrata (leaf) and Saraca asoca (leaf), were also significantly cytotoxic (IC50 ternatea (flower and leaf), Caesalpinia pulcherrima (leaf), E. viride (leaf) and G. oppositifolius (whole plant) showed cytotoxicity only against both of the breast cancer cell lines (MCF-7 and MDA-MB-231). In contrast, C. ternatea (flower and leaf) exhibited high cytotoxic activity against MDA-MB-231 (IC50 values of 0.11 and 0.49 mg/mL, respectively), whereas E. viride and G. oppositifolius whole plant extracts exhibited high activity against MCF-7 cells (IC50 values of 0.06 and 0.15 mg/mL, respectively). The cytotoxic activity test results for 9 of the plant species correlate with their traditional use as anticancer agents, thus making them interesting sources for further drug development. PMID:23846168

  3. Ethnobotanical studies on medicinal plants used by sugalis of yerramalais in kurnool district, Andhra Pradesh, India

    OpenAIRE

    S. Kahleel Basha; G. Sudarshanam

    2011-01-01

    In India, the use of different parts of several medicinal plants to cure specific ailments has been practiced since ancient times. Ehanobotanical studies were carried out to collect information on the use of medicinal plants by the tribal community (Sugalis) who live in the forests of Yerramalais of Kurnool district, Andhra Pradesh, India. The present paper deals with identification of 40 medicinal plants, with local names used by Sugalis for different diseases. The information about...

  4. Ethnopharmacological survey: a selection strategy to identify medicinal plants for a local phytotherapy program

    OpenAIRE

    Flávia Liparini Pereira; José Martins Fernandes; João Paulo Viana Leite

    2012-01-01

    Ethnopharmacological studies are important for documenting and protecting cultural and traditional knowledge associated with the medical use of biodiversity. In this paper, we present a survey on medicinal plants used by locals in a community of Nova Viçosa, Viçosa, MG, Brazil, as a strategy to select medicinal plants for a phytotherapy-based local healthcare program. Eleven knowledgeable local informants were chosen by snowball sampling and interviewed about the use of medicinal plants. Plan...

  5. Medicinal plants used for dogs in Trinidad and Tobago.

    Science.gov (United States)

    Lans, C; Harper, T; Georges, K; Bridgewater, E

    2000-06-12

    This paper documents ethnoveterinary medicines used to treat dogs in Trinidad and Tobago. In 1995, a 4-stage process was used to conduct the research and document the ethnoveterinary practices. Twenty-eight ethnoveterinary respondents were identified using the school-essay method, which is a modified rapid rural appraisal (RRA) technique. Semi-structured interviews were held with these respondents as well as with 30 veterinarians, 27 extension officers and 19 animal-health assistants and/or agricultural officers, and the seven key respondents that they identified. The final step involved hosting four participatory workshops with 55 of the respondents interviewed to discuss the ethnoveterinary data generated from the interviews and to determine dosages for some of the plants mentioned. Supplementary interviews were conducted in 1997 and 1998. Seeds of Carica papaya, and leaves of Cassia alata, Azadirachta indica, Gossypium spp., Cajanus cajan and Chenopodium ambrosiodes are used as anthelmintics. The anthelmintics Gossypium spp. and Chenopodium ambrosiodes are the most frequently used species. Crescentia cujete pulp, Musa spp. stem exudate, the inside of the pods of Bixa orellana, leaves of Cordia curassavica and Eclipta alba plant tops are used for skin diseases. Musa spp. stem exudate, seeds of Manilkara zapota, Pouteria sapota and Mammea americana and leaves of Cordia curassavica, Scoparia dulcis and Nicotiana tabacum are used to control ectoparasites. Dogs are groomed with the leaves of Cordia curassavica, Bambusa vulgaris and Scoparia dulcis. Psidium guajava buds and leaves and the bark of Anacardium occidentale are used for diarrhoea. Owners attempt to achieve milk let-down with a decoction of the leaves of Stachytarpheta jamaicensis. The plant uses parallel those practised in human folk medicine in other Caribbean countries and in other tropical countries. PMID:10821961

  6. Cytotoxicity of Selected Medicinal and Nonmedicinal Plant Extracts to Microbial and Cervical Cancer Cells

    OpenAIRE

    Gary M. Booth; Malmstrom, Robert D.; Erica Kipp; Alexandra Paul

    2012-01-01

    This study investigated the cytotoxicity of 55 species of plants. Each plant was rated as medicinal, or nonmedicinal based on the existing literature. About 79% of the medicinal plants showed some cytotoxicity, while 75% of the nonmedicinal plants showed bioactivity. It appears that Asteraceae, Labiatae, Pinaceae, and Chenopodiaceae were particularly active against human cervical cancer cells. Based on the literature, only three of the 55 plants have been significantly investigated for cytoto...

  7. Biosynthesis of silver fine particles and particles decorated with nanoparticles using the extract of Illicium verum (star anise) seeds

    Science.gov (United States)

    Luna, Carlos; Chávez, V. H. G.; Barriga-Castro, Enrique Díaz; Núñez, Nuria O.; Mendoza-Reséndez, Raquel

    2015-04-01

    Given the upsurge of new technologies based on nanomaterials, the development of sustainable methods to obtain functional nanostructures has become an imperative task. In this matter, several recent researches have shown that the biodegradable natural antioxidants of several plant extracts can be used simultaneously as reducing and stabilizing agents in the wet chemical synthesis of metallic nanoparticles, opening new opportunities to design greener synthesis. However, the challenge of these new techniques is to produce stable colloidal nanoparticles with controlled particle uniformity, size, shape and aggregation state, in similar manner than the well-established synthetic methods. In the present work, colloidal metallic silver nanoparticles have been synthesized using silver nitrate and extracts of Illicium verum (star anise) seeds at room temperature in a facile one-step procedure. The resulting products were colloidal suspensions of two populations of silver nanoparticles, one of them with particle sizes of few nanometers and the other with particles of tens of nm. Strikingly, the variation of the AgNO3/extract weight ratio in the reaction medium yielded to the variation of the spatial distribution of the nanoparticles: high AgNO3/extract concentration ratios yielded to randomly dispersed particles, whereas for lower AgNO3/extract ratios, the biggest particles appeared coated with the finest nanoparticles. This biosynthesized colloidal system, with controlled particle aggregation states, presents plasmonic and SERS properties with potential applications in molecular sensors and nanophotonic devices.

  8. Toxicity studies of medicinal plants used in sub-Saharan Africa.

    Science.gov (United States)

    Boukandou Mounanga, Marlaine; Mewono, Ludovic; Aboughe Angone, Sophie

    2015-11-01

    In sub-Saharan Africa, traditional medicine is widely used in rural and urban areas also. This is essentially due to the prohibitive cost of pharmaceutical-based medicine and the low incomes of a major part of the population. In addition, the efficacies of many of these traditional and plant-based medicines are proven, but the fact remains that certain plants used in traditional medicine have toxic effects. It is in this perspective that we investigated by bibliographic literature on the toxicity of plants used in traditional medicine. It is crucial to gain knowledge on these plant-based medicines prepared and prescribed by practitioners, particularly in terms of toxicity, composition, specific efficacy of disease and to advise practitioners of this alternative medicine on the protection and security of patients. PMID:26087230

  9. The carbon isotope ratios and contents of mineral elements in leaves of Chinese medicinal plants

    International Nuclear Information System (INIS)

    Leaf carbon isotope ratios and 13 kinds of mineral elements were measured on 36 species of common Chinese medicinal plants in a subtropical monsoon forest of Ding Hu Shan in Guangdong Province. The .delta.13C value were from -26.4 to -32.6%, indicating that all of the species belonged the photosynthetic C3 types. The relative lower value of ?13C was observed in the life form of shrubs. The contents of 7 elements (N, P, K, Ca, Na Mg, Si) were dependent upon the species, life form, medicinal function and medicinal part. Herb type medicine and the used medicinal part of leaves or whole plant showed higher levels of above elements than the others. Among the nine groups with different medicinal functions, it was found that more nitrogen was in the leaves of medicinal plants for hemophthisis, hypertension and stomachic troubles, more phosphorus and potassium were in the leaves for cancer and snake bite medicines, but more calcium and magnesium were in the leaves for curing rheumatics. Ferric, aluminium and manganese were the main composition of microelements in leaves. There were higher content of ferric in leaves for hemophthisis medicine, higher zinc in leaves for cold and hypertension medicine, and higher Cup in leaves of stomachic medicine. It was suggested that the pattern of mineral elements in leaves of Chinese medicinal plants reflected the different properties of absorption and accumulation. Some additional effect due to the high content of certain element might be associated with the main function of that medicine

  10. Antimicrobial and cytotoxic effects of Mexican medicinal plants.

    Science.gov (United States)

    Jacobo-Salcedo, Maria del Rosario; Alonso-Castro, Angel Josabad; Salazar-Olivo, Luis A; Carranza-Alvarez, Candy; González-Espíndola, Luis Angel; Domínguez, Fabiola; Maciel-Torres, Sandra Patricia; García-Lujan, Concepción; González-Martínez, Marisela del Rocio; Gómez-Sánchez, Maricela; Estrada-Castillón, Eduardo; Zapata-Bustos, Rocio; Medellin-Milán, Pedro; García-Carrancá, Alejandro

    2011-12-01

    The antimicrobial effects of the Mexican medicinal plants Guazuma ulmifolia, Justicia spicigera, Opuntia joconostle, O. leucotricha, Parkinsonia aculeata, Phoradendron longifolium, P. serotinum, Psittacanthus calyculatus, Tecoma stans and Teucrium cubense were tested against several human multi-drug resistant pathogens, including three Gram (+) and five Gram (-) bacterial species and three fungal species using the disk-diffusion assay. The cytotoxicity of plant extracts on human cancer cell lines and human normal non-cancerous cells was also evaluated using the MTT assay. Phoradendron longifolium, Teucrium cubense, Opuntia joconostle, Tecoma stans and Guazuma ulmifolia showed potent antimicrobial effects against at least one multidrug-resistant microorganism (inhibition zone > 15 mm). Only Justicia spicigera and Phoradendron serotinum extracts exerted active cytotoxic effects on human breast cancer cells (IC50 < or = 30 microg/mL). The results showed that Guazuma ulmifolia produced potent antimicrobial effects against Candida albicans and Acinetobacter lwoffii, whereas Justicia spicigera and Phoradendron serotinum exerted the highest toxic effects on MCF-7 and HeLa, respectively, which are human cancer cell lines. These three plant species may be important sources of antimicrobial and cytotoxic agents. PMID:22312741

  11. Antioxidant and antimicrobial activities of selected medicinal plants from Algeria

    Directory of Open Access Journals (Sweden)

    Krimat Soumia

    2014-06-01

    Full Text Available Objective: To evaluate the antioxidant and antimicrobial activity of methanolic extract extracts of selected Algerian medicinal plants. Methods: Antioxidant activity of extracts was evaluated in terms of radical scavenging potential (2,2-diphenyl-1-picrylhydrazyl and ?-carotene bleaching assay. Total phenolic contents and flavonoid contents were also measured. Antimicrobial activity of these plants was examined against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans. Results: The values of IC50 ranged from 4.30 ?g/mL to 486.6 ?g/mL for the DPPH method, while total antioxidant activity using ?-carotene/linoleic acid bleaching assay ranged from 17.03% to 86.13%. It was found that Pistacia lentiscus showed the highest antioxidant capacities using DPPH assay (IC50=4.30 ?g/mL, while Populus trimula, Origanum glandulosum, Centaurea calcitrapa, Sysimbrium officinalis and Rhamnus alaternus showed the highest percent of total antioxidant activity in ?-carotene/linoleic acid bleaching assay. Total phenolic and flavonoid contents ranged from 3.96 to 259.65 mg GAE/g extract and from 1.13 to 26.84 mg QE/g extract, respectively. The most interesting antimicrobial activity was obtained from Sysimbrium officinalis, Rhamnus alaternus, Origanum glandulosum, Cupressus sempervirens, Pinus halipensis and Centaurea calcitrapa. Conclusions: The results indicated that the plants tested may be potential sources for isolation of natural antioxidant and antimicrobial compounds.

  12. INHIBITION OF TYPE I 5?-REDUCTASE BY MEDICINAL PLANT EXTRACTS

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    Patil Vijaya

    2011-03-01

    Full Text Available Type I 5?-reductase has been implicated in skin disorders such as acne, hirsutism and male pattern baldness and its inhibition offers a potential treatment for these disorders. The aim of this study was to investigate the inhibition of type I 5?-reductase activity by extracts from Indian medicinal plants. Plant extracts were screened and selected based on their ability to inhibit Propionibacterium acnes and Staphylococcus epidermidis. Since type I 5?-reductase metabolises testosterone to ?4-androstene-3, 17-dione, the activity of enzyme was determined using RIA for testosterone and ?4-androstene-3, 17-dione. It was found that methanolic extract of Embelia ribes was a potent inhibitor of type I 5?-reductase (IC50:100?g/mL. Extracts of Vitex negundo, Terminalia chebula, and Terminalia bellerica which also inhibited type I 5?-reductase (IC50: 200-390 ?g /mL. Therefore herbal formulation of these plant extracts may be used in the treatment of skin disorders involving type I 5?-reductase.

  13. Correlation between heavy metal contents and antioxidants in medicinal plants grown in mining areas

    International Nuclear Information System (INIS)

    Full texts: Medicinal plants are widely used as alternate therapeutic agents for various diseases. Three medicinal plants grown in copper mining regions of Khetri in Rajasthan was analyzed for heavy metal contents by instrumental neutron activation analysis. The copper levels were found to be two to three folds higher in these plant leaves as compared to the reported copper levels in the medicinal plants grown in environmentally friendly regions. In our previous study on heavy metals in soil and medicinal plant of Khetri region we have shown bioaccumulation of Cu in the medicinal plants. In addition, the levels of Cr, Fe and Zn were also higher. Antioxidant properties of medicinal plants are one of their major therapeutic functionalities. The role of elevated levels of heavy metals in the medicinal plants was studied with respect to their antioxidant properties. Standard procedures were used for measuring total phenols, flavanoids and DPPH assay of these medicinal plants which were correlated with the heavy metals contents of these plants

  14. Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine.

    Science.gov (United States)

    Arcanjo, D D R; Albuquerque, A C M; Melo-Neto, B; Santana, L C L R; Medeiros, M G F; Citó, Amgl

    2012-08-01

    The brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports the bioactivity of ethanol extracts from seven medicinal plants from the Northeast of Brazil (Acmella uliginosa, Ageratum conyzoides, Eugenia uniflora, Plectranthus neochilus, Moringa oleifera, Justicia pectoralis and Equisetum sp.) against Artemia salina. Biological activity was evaluated for extracts at 1, 10, 100, and 1000 µg/mL in triplicate, and the mean lethal concentration values (LC50) were obtained by probit analysis. The species Acmella uliginosa showed the highest bioactivity, and its flower extract was more active than its leaf extract. PMID:22990821

  15. AN ANALYSIS OF MEDICINAL PLANTS CULTIVATION IN SIVAGANGAI DISTRICT OF TAMIL NADU, SOUTHERN INDIA

    Directory of Open Access Journals (Sweden)

    K. Jayanthi

    2014-10-01

    Full Text Available Farming of medicinal plants particularly elevated worth medicinal plants is creating innovative aspect in the field of Agriculture. It is estimated that 70% to 80% of the people worldwide rely chiefly on traditional health care system and largely on herbal medicines. India has an officially recorded list of 45,000 plant species and various estimations have put the list of 7500 species of medicinal importance. In such a way, the present study was carried out to explore the medicinal plant cultivators in Sivagangai District of Tamilnadu. The proportionate random sampling technique has been adopted to select 50 medicinal plant farmers from 5 villages of Sivagangai district. Secondary data and information are collected from the annual reports of the department of agriculture, Tamilnadu, books, journals and websites. Percentage analysis, averages, ranking method, standard deviation and chi- square tests were used for the analysis. The study reveals that the association between adoption of medicinal plants cultivation and socio-economic variables namely experience, marital status, type of family and family income per month is significant at 5 per cent level as the Pvalue is less than 0.05. The rest of the socio economic variables namely, age, sex, family size and educational qualification, are not significantly associated at 5 per cent level with adoption of medicinal plants cultivation. The study shows that the cultivation of medicinal plants can play an important role in the income strategies of the villagers in high attitude of Sivagangai District of Tamilnadu

  16. Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris

    Science.gov (United States)

    Tian, Minqing; Dai, Haofu; Li, Xiaoming; Wang, Bingui

    2009-05-01

    Twenty-four compounds including eight steroids ( 1-8), nine triterpenoids ( 9-16, 24), three flavonoids ( 20-22), and four benzenecarboxylic derivatives ( 17-19, 23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites, compounds 1, 4-20 and 22-24 were isolated and identified for the first time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells, compound 21 (3',4',5,7-tetrahydroxyflavone) exhibited significant activity with IC50 2.8 ?g/mL, while oleanolic acid ( 14), 3,3'-di- O-methyl ether ellagic acid ( 18), and 3,3',4- O-tri- O-methyl ether ellagic acid ( 19) showed weak activity. None of these compounds displayed significant antibacterial activites.

  17. Natural and artificial radioactivity determination of some medicinal plants

    International Nuclear Information System (INIS)

    Several medicinal plants used in Italy were analysed to determine natural and artificial radioactivity in those parts (leaves, fruits, seeds, roots, peduncles, flowers, barks, berries, thallus) used generally as remedies. The radionuclides were determined by alpha (238U, 210Po) and gamma (214Pb-Bi, 210Pb, 40K and 137Cs) spectrometry. 238U ranged between dry-1; 210Po between dry-1; 214Pb-214Bi between dry-1; 210Pb between dry-1; 40K between 66.2 and 3582.0 Bq kgdry-1; 137Cs between dry-1. The percentage of 210Po extraction in infusion and decoction was also determined; the arithmetical mean value of percentage of 210Po extraction resulted 20.7 ± 7.5.

  18. Anti-bacterial activity of some Brazilian medicinal plants.

    Science.gov (United States)

    de Lima, Maria Raquel Ferreira; de Souza Luna, Josiane; dos Santos, Aldenir Feitosa; de Andrade, Maria Cristina Caño; Sant'Ana, Antônio Euzébio Goulart; Genet, Jean-Pierre; Marquez, Béatrice; Neuville, Luc; Moreau, Nicole

    2006-04-21

    Extracts from various organs of 25 plants of Brazilian traditional medicine were assayed with respect to their anti-bacterial activities against Escherichia coli, a susceptible strain of Staphylococcus aureus and two resistant strains of Staphylococcus aureus harbouring the efflux pumps NorA and MsrA. Amongst the 49 extracts studied, 14 presented anti-bacterial activity against Staphylococcus aureus, including the ethanolic extracts from the rhizome of Jatropha elliptica, from the stem barks of Schinus terebinthifolius and Erythrina mulungu, from the stems and leaves of Caesalpinia pyramidalis and Serjania lethalis, and from the stem bark and leaves of Lafoensia pacari. The classes of compounds present in the active extracts were determined as a preliminary step towards their bioactivity-guided separation. No extracts were active against Escherichia coli. PMID:16356672

  19. Medicinal plants from Peru: a review of plants as potential agents against cancer.

    Science.gov (United States)

    Gonzales, Gustavo F; Valerio, Luis G

    2006-09-01

    Natural products have played a significant role in drug discovery and development especially for agents against cancer and infectious disease. An analysis of new and approved drugs for cancer by the United States Food and Drug Administration over the period of 1981-2002 showed that 62% of these cancer drugs were of natural origin. Natural compounds possess highly diverse and complex molecular structures compared to small molecule synthetic drugs and often provide highly specific biological activities likely derived from the rigidity and high number of chiral centers. Ethnotraditional use of plant-derived natural products has been a major source for discovery of potential medicinal agents. A number of native Andean and Amazonian medicines of plant origin are used as traditional medicine in Peru to treat different diseases. Of particular interest in this mini-review are three plant materials endemic to Peru with the common names of Cat's claw (Uncaria tomentosa), Maca (Lepidium meyenii), and Dragon's blood (Croton lechleri) each having been scientifically investigated for a wide range of therapeutic uses including as specific anti-cancer agents as originally discovered from the long history of traditional usage and anecdotal information by local population groups in South America. Against this background, we present an evidence-based analysis of the chemistry, biological properties, and anti-tumor activities for these three plant materials. In addition, this review will discuss areas requiring future study and the inherent limitations in their experimental use as anti-cancer agents. PMID:17017852

  20. Teste de envelhecimento acelerado em sementes de erva-doce Accelerated aging test on anise seeds

    Directory of Open Access Journals (Sweden)

    Salvador Barros Torres

    2004-12-01

    Full Text Available O presente trabalho teve por objetivo estudar a metodologia do teste de envelhecimento acelerado para avaliação do potencial fisiológico de sementes de erva-doce, bem como avaliar a eficiência do uso de solução saturada de sal no controle da absorção de água pelas sementes durante a realização do teste. Para tanto, quatro lotes de sementes de erva-doce foram submetidos aos testes de germinação, emergência das plântulas em casa de vegetação e envelhecimento acelerado (41ºC; 48, 72 e 96h; conduzindo-se o procedimento tradicional e a alternativa com o uso de solução saturada de NaCl. Diante dos resultados obtidos, verificou-se que as sementes de erva-doce expostas a solução saturada de NaCl durante o teste de envelhecimento acelerado captam menor quantidade de água, verificando-se taxa de deterioração menos acentuada, resultados menos drásticos e mais uniformes que os obtidos com o procedimento tradicional. A exposição no teste de envelhecimento acelerado durante 72h, a 41ºC, com o uso de solução saturada de NaCl, constitui opção promissora para avaliação do potencial fisiológico das sementes dessa espécie.The objective of the present study was to investigate different procedures for the accelerated aging test to evaluate the physiological quality of anise (Pimpinella asinum L. seeds. Fours anise seedlots were tested for germination, seedling emergence, traditional and saturated salt (SSAA accelerated aging at 41ºC, for 48, 72 and 96h. It was concluded that, among the accelerated aging protocols studied, the SSAA for 72h was appropriate to assess the physiological potential of anise seeds. It was also observed that seed water content after SSAA was lower and more uniform, thus presenting advantages in relation to the conventional procedure.

  1. Review: Biotechnological strategies for conservation of rare and endangered medicinal plants

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    MAHENDRA KUMAR RAI

    2010-07-01

    Full Text Available Rai MK (2010 Review: Biotechnological strategies for conservation of rare and endangered medicinal plants. Biodiversitas 11: 157-166. The use of medicinal plants is as old as human civilization. The biotechnological tools play a crucial role in conservation of rare and endangered medicinal plants. The rapid depletion of plant genetic diversity has made essential to develop new in situ and ex situ conservation methods. Advances in biotechnology offer new methods for conservation of rare and endangered medicinal plants. The present review is focused on biotechnological tools like in vitro culture, micropropagation, mycorrhization, genetic transformation and development of DNA banks. These are imperative and important alternatives for the conservation of rare and endangered medicinal plants.

  2. From Delirium to Coherence: Shamanism and Medicine Plants in Silko's "Ceremony"

    Science.gov (United States)

    Weso, Thomas F.

    2004-01-01

    A nondescript rock shelter in Texas provides the evidence for shamanism in Leslie Marmon Silko's novel, "Ceremony". There, archaeologists found identifiable images of antlered human figures and entheogenic plant substances, which are medicinal plants, associated with shamanistic practices.

  3. Aromatic Plants as a Source of Bioactive Compounds

    Directory of Open Access Journals (Sweden)

    Panagiota Florou-Paneri

    2012-09-01

    Full Text Available Aromatic plants, also known as herbs and spices, have been used since antiquity as folk medicine and as preservatives in foods. The best known aromatic plants, such as oregano, rosemary, sage, anise, basil, etc., originate from the Mediterranean area. They contain many biologically active compounds, mainly polyphenolics, which have been found to possess antimicrobial, antioxidant, antiparasitic, antiprotozoal, antifungal, and anti-inflammatory properties. Currently, the demand for these plants and their derivatives has increased because they are natural, eco-friendly and generally recognized as safe products. Therefore, aromatic plants and their extracts have the potential to become new generation substances for human and animal nutrition and health. The purpose of this review is to provide an overview of the literature surrounding the in vivo and in vitro use of aromatic plants.

  4. Comparative evaluation of dietary oregano, anise and olive leaves in laying Japanese quails

    OpenAIRE

    EV Christaki; EM Bonos; PC Florou-Paneri

    2011-01-01

    Aim of the present study was the comparative evaluation of the effect of ground oregano, anise and olive leaves as feed additives on performance and some egg quality characteristics of laying Japanese quails. A total of 189 Coturnix japonica quails (126 females and 63 males), 149 days old, were randomly allocated into seven equal groups with three subgroups of 9 birds each (6 females and 3 males). A commercial laying diet was fed to the control group. The remaining six groups were fed the sam...

  5. Diversity and use of ethno-medicinal plants in the region of Swat, North Pakistan

    OpenAIRE

    Akhtar, Naveed; Rashid, Abdur; Murad, Waheed; Bergmeier, Erwin

    2013-01-01

    Abstract Background Due to its diverse geographical and habitat conditions, northern Pakistan harbors a wealth of medicinal plants. The plants and their traditional use are part of the natural and cultural heritage of the region. This study was carried out to document which medicinal plant species and which plant parts are used in the region of Swat, which syndrome categories are particularly concerned, and which habitat spectrum is frequented by collectors. Finally, we assessed to which exte...

  6. Cytotoxic Activity of Some Medicinal Plants from Hamedan District of Iran

    OpenAIRE

    Behzad, Sahar; Pirani, Atefeh; Mosaddegh, Mahmoud

    2014-01-01

    Medicinal plants have been investigated for possible anti-cancer effects. The aim of the present study was to examine the cytotoxic activity of several medicinal plants on different tumor cell lines. 11 selected plant species which have been used in folkloric prescriptions were collected from different sites of Hamedan district of Iran. The methanolic extracts of the plants were prepared and their cytotoxic effects on four human cancer cell lines (A549, human lung adenocarcinoma; MCF7, human ...

  7. Traditional drug therapies from various medicinal plants of central Karakoram National Park, Gilgit-Baltistan, Pakistan

    International Nuclear Information System (INIS)

    Traditional medicines derived from indigenous plants play an important role in treating infectious diseases. This study examined traditional medicinal uses of indigenous plants and documented different traditional recipes used by local communities to treat different diseases in Baltistan Region. Forty-seven medicinal plants belonging to 22 families were collected. Twenty-one families were angiosperms, one was a pteridophyte (Equisetaceae), and one a gymnosperm (Ephedraceae). Crude extracts of these medicinal plants were used by the local people for treating diseases in a traditional system of medicine. Ranunculaceae, Asteraceae, Polygonaceae and Rosaceae were the most important families, each having five species with medicinal value. The species were found across a wide range of altitudes, from 2000 m to over 4000 m. (author)

  8. ANTIOXIDANT, CYTOTOXIC PROPERTIES AND PHYTOCHEMICAL SCREENING OF TWO LEBANESE MEDICINAL PLANTS

    OpenAIRE

    Rammal Hassan; Farhan Hussein; Mohsen Hawraa; Hijazi Akram; Kobeissy Ahmad; Daher Ahmad; Badran Bassam

    2013-01-01

    Nowadays herbal medicine presents a significant adjuvant tool for hard treatment, especially in the case of cancer where modern medicine has access to traditional medicine to deprive the patient of the side effects of therapeutic approaches such as surgery and chemotherapy. Thus, Lebanese 10452 km2 are so rich in medicinal plants such as Eryngium creticum L. and Euphorbia macroclada Boiss that are traditionally used in the treatment of various diseases (leukemia, asthma, skin diseases, antido...

  9. Medicinal and Aromatic Plants Cultivation in Bihar, India: Economic Potential and Condition for Adoption

    OpenAIRE

    Singh, K.M.; Jha, A.K.

    2008-01-01

    The MAPs provide opportunities for developing a variety of safe and cost effective, prophylactic, and curative medicines for a number of maladies. It is estimated that the primary health care of over 80 per cent of the world’s population still depends on plant based traditional medicines (WHO, 2002). Growing consciousness about health and side effects of modern medicines has again set the stage for innovation and use of herbal medicines. The global market for herbal products is continuously e...

  10. Globalisation and sustainable exports of Indian medicinal and aromatic plants: A protection study

    OpenAIRE

    Bera, Soumitra Kumar

    2010-01-01

    India has a rich heritage of traditional systems of medicine viz. Ayurveda, Unani, Siddha, Tibetan which are mostly based on botanical formulations. Although biologically, the region is extremely rich in medicinal plants, due to years of unwise use, the availability of raw materials in desired quality and quantity has become difficult to obtain raising serious doubt about the safety and efficacy of the medicines currently in use. There is unprecedented demand for natural medicines, green hea...

  11. Total phenolics and antioxidant activity of five medicinal plant

    International Nuclear Information System (INIS)

    This paper describes total phenolics content and antioxidant activity in the ethanolic extract of leaves, bark and roots of five medicinal plants: Terminalia brasiliensis Camb., Terminalia fagifolia Mart. and Zucc., Copernicia cerifera (Miller) H.E. Moore, Cenostigma macrophyllum Tul. var. acuminata Teles Freire and Qualea grandiflora Mart. The total phenolics content of the plant extracts, determined by the Folin-Ciocalteu method, varied from 250.0 ±8,2 to 763,63 ±13.03 mg of gallic acid equivalent/g dry EtOH extract. The antioxidant activity of extracts was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay system. Extract of bark from T. brasiliensis, the most active, with an EC50 value of 27.59 ± 0.82 ?g/mL, was comparable to rutin (EC50 = 27.80 ± 1.38) and gallic acid (EC50 = 24.27 ± 0.31), used as positive controls. The relationship between total phenolic content and antioxidant activity was positive and significant for T. brasiliensis, C. macrophyllum and C. cerifera. (author)

  12. Acetylcholinesterase inhibition by somes promising Brazilian medicinal plants.

    Science.gov (United States)

    Feitosa, C M; Freitas, R M; Luz, N N N; Bezerra, M Z B; Trevisan, M T S

    2011-08-01

    A microplate assay and a thin-layer chromatography (TLC) "in situ" assay based on the Ellman assay was used to screen for acetylcholinesterase inhibitors from ethyl acetate and methanol extracts of Brazilian medicinal plants of families that, according to the literature, have traditional uses that might be connected with acetylcholinesterase inhibition. Eighteen species belonging to Convolvulaceae, Crassulaceae, Euphorbiaceae, Leguminosae, Malvaceae, Moraceae, Nyctaginaceae and Rutaceae families were tested. The most active plants were Ipomoea asarifolia (IC50 = 0.12 mg/mL), Jatropha curcas (IC50 = 0.25 mg/mL), Jatropha gossypiifolia (IC50 = 0.05 mg/mL), Kalanchoe brasiliensis (IC50 = 0.16 mg/mL) and Senna alata (IC50 = 0.08 mg/mL). The most promising extracts were the Jatropha gossypiifolia and Senna alata species assuming there were compounds with a similar activity to galanthamine, which should contain about 1% of an active compound, or if present at lower levels even more active compounds than galanthamine (IC50 = 0.37 x 10-3 mg/mL) should be present. PMID:21881804

  13. ELECTROCHEMICAL FINGERPRINT STUDIES OF SELECTED MEDICINAL PLANTS RICH IN FLAVONOIDS.

    Science.gov (United States)

    Konieczy?ski, Pawe?

    2015-01-01

    The combination of a size-exclusion column (SEC) with electrochemical (voltammetric) detection at a boron-doped diamond electrode (BDDE) was applied for studying the correlations between electroactive Cu and Fe species with phenolic groups of flavonoids. For comparison with electrochemical results, SEC-HPLC-DAD detection was used. The studied plant material comprised of: Betula verrucosa Ehrh., Equisetun arvense L., Polygonum aviculare L., Viola tricolor L., Crataegus oxyacantha L., Sambucus nigra L. and Helichrysum arenarium (L.) Moench. Based upon the results, high negative correlation was found for the chromatographic peak currents at 45 min with the sum of Cu and Fe for the aqueous extracts of Sambucus, Crataegus and Betula species, and for the peak currents at 65 min of the aqueous extracts of Sambucus, Crataegus, Helichrysum and Betula botanical species. This behavior confirms that it is mainly the flavonoids with easily oxidizable phenolic groups which are strongly influenced by the presence of Cu and Fe. Moreover, the electrochemical profiles obtained thanks to the use of HPLC hyphenated with voltammetric detection can be potentially applied for fingerprint studies of the plant materials used in medicine. PMID:26647621

  14. [Use of medicinal plants against scorpionic and ophidian venoms].

    Science.gov (United States)

    Memmi, A; Sansa, G; Rjeibi, I; El Ayeb, M; Srairi-Abid, N; Bellasfer, Z; Fekhih, A

    2007-01-01

    The scorpionic and ophidian envenomations are a serious public health problem in Tunisia especially in Southeastern regions. In these regions Artemisia campestris L is a plant well known which has a very important place in traditional medicine for its effectiveness against alleged venom of scorpions and snakes. In this work, we tested for the first time, the anti-venomous activity of Artemisia campestris L against the scorpion Androctonus australis garzonii and the viper Macrovipera lebetina venoms. Assays were conducted by fixing the dose of extract to3 mg/mouse while doses of venom are variable. The leaves of Artemisia campestris L were extracted by various organic solvents (Ether of oil, ethyl acetate, methanol and ethanol) and each extract was tested for its venom neutralizing capacity. For the ethanolic extract, a significant activity with respect to the venoms of scorpion Androctonus australis garzonii (Aag), was detected. Similarly, a significant neutralizing activity against the venom of a viper Macrovipera lebetina (Ml), was obtained with the dichloromethane extract. These results suggest the presence of two different type of chemical components in this plant: those neutralizing the venom of scorpion are soluble in ethanol whereas those neutralizing the venom of viper are soluble in dichloromethane. PMID:19388583

  15. Antityrosinase and antimicrobial activities from Thai medicinal plants.

    Science.gov (United States)

    Dej-Adisai, Sukanya; Meechai, Imron; Puripattanavong, Jindaporn; Kummee, Sopa

    2014-04-01

    Various dermatological disorders and microbial skin infection can cause hyperpigmentation. Therefore, screenings for whitening and antimicrobial agents from Thai medicinal plants have been of research interest. Seventy-seven ethanol plant extracts were investigated for antityrosinase activity, eleven samples showed the tyrosinase inhibition more than 50 % were further preliminary screening for antimicrobial activity by agar disc diffusion and broth micro-dilution methods. Artocarpus integer (Thunb.) Merr. (Moraceae) root extract, which showed the potential of tyrosinase inhibition with 90.57 ± 2.93 % and antimicrobial activity against Staphylococcus aureus, S. epidermidis, Propionibacterium acnes and Trichophyton mentagophytes with inhibition zone as 9.10 ± 0.00, 10.67 ± 0.09, 15.25 ± 0.05 and 6.60 ± 0.17 mm, respectively was selected for phytochemical investigation. Three pure compounds were isolated as artocarpin, cudraflavone C and artocarpanone. And artocarpanone exhibited anti-tyrosinase effect; artocarpin and cudraflavone C also showed the potential of antibacterial activity against S. aureus, S. epidermidis and P. acnes with MIC at 2, 4 and 2 ?g/ml, respectively and MBC at 32 ?g/ml for these bacteria. So, these pure compounds are interesting for further study in order to provide possibilities of new whitening and antibacterial development. This will be the first report of phytochemical investigation of A. integer root. PMID:23835832

  16. Hypolipidimic effect of some medicinal plants on diabetic rats

    Directory of Open Access Journals (Sweden)

    Eman G.E.Helal * and Mohamed M. A. Shahat

    2006-06-01

    Full Text Available Our aim was to evaluate the hypolipidimic effect of aqueous extract of a famous mixture used in Saudi Arabia folk medicine that consists of Nigella sativa, Commiphora myrrha, Boswellia carterii Birdw, Ferule assa-foetida and Aloe vera and also the extract of each plant alone on alloxan induced diabetic rats. Material and Methods :-The present study was carried out on 80 adult male albino rats (120 ± 20 g.b.wt. , the rats were divided randomly into 8 groups, the first group served as control group, the second group as alloxan induced diabetic rats, the third group was diabetic rats treated with mixture of folk medicinal plant ( 0.01g /100 g b. wt. ,the fourth group: diabetic rats treated with Nigella sativa ( 0.01g /100 g b. wt. , the fifth group: diabetic rats treated with Aloe vera ( 0.005g /100 g b. wt. , the sixth group: diabetic rats treated with Ferule assa-foetida ( 0.01 g /100 g b. wt., the seventh: diabetic rats treated with Boswellia carterii Birdw ( 1ml/100 g b. wt. and the eighth group: diabetic rats treated with Commiphora myrrha ( 0.01 g ml/100 g b. wt. Results :- Serum total lipid, serum total cholesterol, LDL­cholesterol, and triglyceride recorded significant increases in diabetic, Nigella sativa, Commiphora myrrha, Boswellia carterii birdw and Aloe vera treated group. While the mixture and Ferule assa-foetida treated group, showed insignificant changes in serum total lipid, triglyceride, serum total cholesterol and LDL­cholesterol. On other hand, the mixture treated group and Ferule assa-foetida treated group showed significant decreased in the previous parameters. The serum HDL­cholesterol was significantly reduced in diabetic group throughout the experimental periods, otherwise, all treated group revealed insignificant changes till the end of experiment when compare with undiabetic rats. Conclusion: The aqueous extract of a mixture consists of Nigella sativa, Commiphora myrrha, Boswellia carterii Birdw, Ferule assa-foetida and Aloe vera are useful for improvement of the lipid profile of alloxan induced diabetic rats fram each plant alone.

  17. Asháninka medicinal plants: a case study from the native community of Bajo Quimiriki, Junín, Peru

    Directory of Open Access Journals (Sweden)

    Luziatelli Gaia

    2010-08-01

    Full Text Available Abstract Background The Asháninka Native Community Bajo Quimiriki, District Pichanaki, Junín, Peru, is located only 4 km from a larger urban area and is dissected by a major road. Therefore the loss of traditional knowledge is a main concern of the local headman and inhabitants. The present study assesses the state of traditional medicinal plant knowledge in the community and compares the local pharmacopoeia with the one from a related ethnic group. Methods Fieldwork was conducted between July and September 2007. Data were collected through semi-structured interviews, collection of medicinal plants in the homegardens, forest walks, a walk along the river banks, participant observation, informal conversation, cross check through voucher specimens and a focus group interview with children. Results Four-hundred and two medicinal plants, mainly herbs, were indicated by the informants. The most important families in terms of taxa were Asteraceae, Araceae, Rubiaceae, Euphorbiaceae, Solanaceae and Piperaceae. Eighty-four percent of the medicinal plants were wild and 63% were collected from the forest. Exotics accounted to only 2% of the medicinal plants. Problems related to the dermal system, digestive system, and cultural belief system represented 57% of all the medicinal applications. Some traditional healers received non-indigenous customers, using their knowledge as a source of income. Age and gender were significantly correlated to medicinal plant knowledge. Children knew the medicinal plants almost exclusively by their Spanish names. Sixteen percent of the medicinal plants found in this community were also reported among the Yanesha of the Pasco Region. Conclusions Despite the vicinity to a city, knowledge on medicinal plants and cultural beliefs are still abundant in this Asháninka Native Community and the medicinal plants are still available in the surroundings. Nevertheless, the use of Spanish names for the medicinal plants and the shift of healing practices towards a source of income with mainly non-indigenous customers, are signs of acculturation. Future studies on quantification of the use of medicinal plants, dynamics of transmission of ethno-medicinal knowledge to the young generations and comparison with available pharmacological data on the most promising medicinal plants are suggested.

  18. Use of medicinal plants and pharmaceuticals by indigenous communities in the Bolivian Andes and Amazon

    Directory of Open Access Journals (Sweden)

    Vandebroek Ina

    2004-01-01

    Full Text Available OBJECTIVE: To investigate, by means of household surveys, the use of medicinal plants and pharmaceuticals in Apillapampa, a large Andean community of Quechua peasants, and in six small communities of Yuracaré-Trinitario "slash-and-burn" cultivators of the National Park Isiboro-Sécure (the NPIS in the Bolivian Amazon. METHODS: A total of 12% of households in Apillapampa and nearly all households in the NPIS were interviewed about their use of medicinal plants and pharmaceuticals for treating illnesses. Informants were also asked to name any medicinal plants they knew. FINDINGS: In spite of the presence of a primary health care service (PHC with medical doctor in Apillapampa, an equal number of informants used medicinal plants and pharmaceuticals. In the NPIS, the prevalent use of medicinal plants or pharmaceuticals in any community depended on the distance of the community from the nearest village and from a PHC with medical doctor (r = 0.85 and r = -0.96; both P = 0.05. The NPIS communities' knowledge of plants expressed as the average number of medicinal plants mentioned correlated positively and negatively with distance from the nearest village and use of pharmaceuticals, respectively (r = 0.95, P<0.005 and r = -0.90, P<0.05, respectively. CONCLUSION: The cultural importance of traditional medicine and the physical isolation of communities, both in general and from PHCs, are factors that influence the use of and knowledge about medicinal plants.

  19. STUDY OF PLANT BIODIVERSITY OF HAZARIBAG DISTRICT JHARKHAND INDIA AND ITS MEDICINAL USES

    OpenAIRE

    Hari Shankar Lal; Sanjay Singh

    2012-01-01

    Jharkhand is rich in biodiversity of medicinal plants. The forest area is about 40% of the total area of Jharkhand. 32 tribal communities found in Jharkhand. They are used medicinal plants by traditional knowledge. Traditional medicinal practioners known as vaidays or kavirajas from the primary health care provider in rural Jharkhand.The objective of this present study was to conduct a value addition survey amongst tribal of Hazaribag and around the district of Jharkhand. Knowledge about to c...

  20. The Anthelmintic Activity of Selected Indigenous Medicinal Plants Used by The anyankole of Western Uganda

    OpenAIRE

    Olila Deogracious; Tuwangye Innocent

    2006-01-01

    Recently, there has been growing interest in the traditional cures of livestock diseases. This is because industrially produced drugs are too expensive for some sectors of the farming community especially in the developing world. Medicinal plants are often cheaper and more easily available than the commercially produced drugs. The self-help study in form of traditional medicines (especially from medicinal plants), offer a way out by making use of resources available within the communities the...

  1. GERMPLASM EVALUATION OF MEDICINAL AND AROMATIC PLANTS IN HIGHLAND BALOCHISTAN, PAKISTAN

    OpenAIRE

    ASLAM GILL; AMINULLAH; SOHAIL ASLAM; KHALIL AHMAD; MUHAMMAD ISLAM; SHAISTA KOUKAB; SARFRAZ AHMAD

    2008-01-01

    Research studies are carried out for cultivation potential of medicinal and aromatic plants [Thyme, Oregano, Rosemary, Sage (belonging to the family Lamiaceae)] in Balochistan. The species studied showed good adaptability in cold and dry area and production potential in highland Balochistan. A medicinal herb garden was also established at Arid Zone Research Centre, Quetta with more than 60 potential medicinal and aromatic plants. This germplasm category includes culinary and herbal teas (Thym...

  2. The influence of extraction solvents on the anticancer activities of Palestinian medicinal plants

    OpenAIRE

    Alzeer, J; Vummidi, B R; Arafeh, R; Rimawi, W; Saleem, H.; Luedtke, Nathan W

    2014-01-01

    Palestine has a rich and prestigious heritage of herbal medicines. To investigate the impact of variable extraction techniques on the cytotoxic effects of medicinal plant extracts, 5 well-known medicinal plants from Palestine were extracted with 90% ethanol, 80% methanol, acetone, coconut water, apple vinegar, grape vinegar or 5% acetic acid. The resulting 35 extracts were screened for cytotoxic activities against three different cancer cell lines (B16F10, MCF-7 and HeLa) using a standard res...

  3. PlantID – DNA-based identification of multiple medicinal plants in complex mixtures

    Directory of Open Access Journals (Sweden)

    Howard Caroline

    2012-07-01

    Full Text Available Abstract Background An efficient method for the identification of medicinal plant products is now a priority as the global demand increases. This study aims to develop a DNA-based method for the identification and authentication of plant species that can be implemented in the industry to aid compliance with regulations, based upon the economically important Hypericum perforatum L. (St John’s Wort or Guan ye Lian Qiao. Methods The ITS regions of several Hypericum species were analysed to identify the most divergent regions and PCR primers were designed to anneal specifically to these regions in the different Hypericum species. Candidate primers were selected such that the amplicon produced by each species-specific reaction differed in size. The use of fluorescently labelled primers enabled these products to be resolved by capillary electrophoresis. Results Four closely related Hypericum species were detected simultaneously and independently in one reaction. Each species could be identified individually and in any combination. The introduction of three more closely related species to the test had no effect on the results. Highly processed commercial plant material was identified, despite the potential complications of DNA degradation in such samples. Conclusion This technique can detect the presence of an expected plant material and adulterant materials in one reaction. The method could be simply applied to other medicinal plants and their problem adulterants.

  4. Relationship between chemical structure and biological activity of alkali metal o-, m- and p-anisates. FT-IR and microbiological studies

    Science.gov (United States)

    Kalinowska, M.; Piekut, J.; Lewandowski, W.

    2011-11-01

    In this work we investigated relationship between molecular structure of alkali metal o-, m-, p-anisate molecules and their antimicrobial activity. For this purpose FT-IR spectra for lithium, sodium, potassium, rubidium and caesium anisates in solid state and solution were recorded, assigned and analysed. Microbial activity of studied compounds was tested against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Proteus vulgaris. In order to evaluate the dependency between chemical structure and biological activity of alkali metal anisates the statistical analysis (multidimensional regression and principal component) was performed for selected wavenumbers from FT-IR spectra and parameters that describe microbial activity of anisates. The obtained statistical equations show the existence of correlation between molecular structure of anisates and their biological properties.

  5. Inorganic constituents determination in medicinal plants and their extracts

    International Nuclear Information System (INIS)

    Different types of therapies have been introduced as an alternative treatment to combat different types of human disorders. Among them, the use of herbal teas has been highlighted by the cost/benefit, easiness of acquisition and administration. The aim of this study was to determine the inorganic constituents, and evaluate the element concentrations of As, Ba, Br, Ca, Co, Cr, Cs, Fe, Hf, K, Mg. Mn, Na, Rb, Sb, Sc, Se, Ta, Th, Ti, U, V, Zn and Zr by neutron activation analysis; and Cd, Cu, Ni and Pb, by atomic emission spectrometry, with inductively coupled plasma source and Hg, by atomic absorption spectrometry, with cold vapor generation in medicinal plants and their extracts, whose marketing was recently regulated by National Health Surveillance Agency (ANVISA). The relevance of these analyses is justified by the need of contributing to the recommendation of such plants as sources of minerals in the diet and, also, to verify if their concentrations cam pose some harm to the organism. The techniques showed adequate sensitivity in determining the concentration for most of the elements. Toxic elements were found in concentration not harmful to the human body. The results, also, allowed possible to correlate the elemental concentration in the analyzed species, by the determination the correlation coefficients and applications of cluster analysis. From these results it was confirmers in the groups of elements, regarding the variation of the concentrations observed in some plants and their extracts. The elements that play important roles in the human metabolism were determined in concentrations that can help both, to avoid the lack of these elements in the organisms, from the diet, and in treatment of disease. (author)

  6. Screening Togolese medicinal plants for few pharmacological properties

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    Simplice D Karou

    2012-01-01

    Full Text Available Background: Terminalia macroptera Guill. et Perr. (Combretaceae, Sida alba L. (Malvaceae, Prosopis africana Guill et Perr. Taub. (Mimosaceae, Bridelia ferruginea Benth. (Euphorbiaceae, and Vetiveria nigritana Stapf. (Asteraceae are traditionally used in Togolese folk medicine to treat several diseases including microbial infections. Objective: This study aimed to investigate the antimicrobial, antioxidant, and hemolytic properties of the crude extracts of the above-mentioned plants. Materials and Methods: The antimicrobial and the antioxidant activities were assayed using the NCCLS microdilution method and the DPPH free radical scavenging, respectively. Human A+ red blood cells were used to perform the hemolytic assay. Phenolics were further quantified in the extracts using spectrophotometric methods. Results: Minimal inhibitory concentrations in the range of 230-1800 ?g/ml were recorded in the NCCLS broth microdilution for both bacterial and fungal strains with methanol extracts. The DPPH radical scavenging assay yielded interesting antioxidant activities of the extracts of P. africana and T. macroptera (IC 50 values of 0.003 ± 0.00 ?g/ml and 0.05 ± 0.03 ?g/ml, respectively. These activities were positively correlated with the total phenolic contents and negatively correlated with the proanthocyanidin content of the extracts. The hemolytic assay revealed that great hemolysis occurred with the methanol extracts of T. macroptera, S. longepedunculata, and B. ferruginea. Conclusion: These results support in part the use of the selected plants in the treatment of microbial infections. In addition, the plant showed an interesting antioxidant activity that could be useful in the management of oxidative stress.

  7. Potential Use of Turkish Medicinal Plants in the Treatment of Various Diseases

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    Gulay Ozkan

    2016-02-01

    Full Text Available Medicinal plants are sources of health-promoting substances, including phytochemicals and phytoalexins that comprise polyphenols, flavonoids, carotenoids, vitamins A, C, E and several other constituents. Many studies have indicated that medicinal plants have been used to treat human diseases for thousands of years owing to their antimicrobial and antioxidant activities. Medicinal plants reduce the oxidative stress in cells and prevent cancer, cardiovascular and inflammatory diseases, neurodegenerative and digestive system disorders. These potential beneficial effects have been attributed to the presence of bioactive compounds that show antioxidant properties by acting as free radical scavengers or metal chelators, reducing the reactions that produce reactive oxygen and nitrogen species (ROS/RNS. Considering the importance of medicinal plants in terms of their beneficial health effects, some of the medicinally important plants grown in Turkey are covered in this review with respect to their antioxidant potential and phytochemical profile.

  8. Arnica montana L., planta medicinal europea con relevancia / Arnica montana L., relevant European medicinal plant

    Scientific Electronic Library Online (English)

    José, Waizel-Bucay; María de Lourdes, Cruz-Juárez.

    2014-10-01

    Full Text Available Se exponen diferentes aspectos relativos a la especie Arnica montana (Asteraceae), importante planta medicinal de uso ancestral; a pesar de ser endémica de Europa central y meridional se ha logrado introducir y cultivar con éxito en Estados Unidos de América y Escocia. Respecto a la conservación de [...] la especie cabe mencionar que está bajo estricta protección y se incluye en diversos libros y listas rojas de algunos países europeos, así como en la Lista Roja de Especies Amenazadas de la IUCN. Se presenta un panorama general de A. montana desde el punto de vista científico (descripción botánica, distribución geográfica y sinonimia científica y nombres comunes en distintos idiomas). Debido a que se utiliza para aliviar muchos padecimientos y a que tiene una diversidad de aplicaciones, se mencionan sus usos medicinales, cosméticos, ornamentales y en perfumería. Su historia, las regiones que se dedican a su comercialización y su importancia económica justifican el interés de realizar estudios que aseguren las condiciones adecuadas para su introducción al cultivo en México; como contribución a este tema se presentan las formas de propagación y los requerimientos para su plantación. También se proporcionan datos sobre su fitoquímica, toxicología, contraindicaciones y efectos secundarios. Es de resaltar que A. montana produce numerosos metabolitos secundarios con actividad biológica, pertenecientes a los grupos de los aceites esenciales, ácidos fenólicos, cumarinas, flavonas, flavonoides, glucósidos, mucílagos, fitosteroles, lactonas sesquiterpénicas, taninos y triterpenos, entre otros. Abstract in english Different aspects of Arnica montana L. (Asteraceae) are presented in this work. It is an important perennial medicinal herb used since ancient times; it is endemic to central and southern Europe and has been successfully introduced and cultivated in several countries, such as the United States of Am [...] erica, Scotland, and others. It is under strict protection and is included in the IUCN Red List of Threatened Species, in the Red Data Books, and Red Data Lists of many European countries. Method: we applied the technique of direct, active reading of specialized documentary sources such as books, magazines and electronic databases. Results: A descriptive overview of the species: its botanical description, geographic distribution, scientific synonyms and common names in different languages; its history, its phytochemistry, its various uses: medicinal, cosmetic and ornamental; its toxicological aspects and its counter-indications or side effects. We also provide information regarding its economic importance, as well as data about its form of propagation. Furthermore, we include the requirements for its cultivation and the main countries that trade it. The plant produces numerous secondary metabolites with biological activity, including essential oils, phenolic acids, coumarins, flavones, flavonoids, glycosides, mucilages, phytosterols, sesquiterpene lactones, tannins and triterpenoids.

  9. Ethnobotanical studies on medicinal plants used by sugalis of yerramalais in kurnool district, Andhra Pradesh, India

    Directory of Open Access Journals (Sweden)

    S. Kahleel Basha

    2011-04-01

    Full Text Available

    In India, the use of different parts of several medicinal plants to cure specific ailments has been practiced since ancient times. Ehanobotanical studies were carried out to collect information on the use of medicinal plants by the tribal community (Sugalis who live in the forests of Yerramalais of Kurnool district, Andhra Pradesh, India. The present paper deals with identification of 40 medicinal plants, with local names used by Sugalis for different diseases. The information about different types of medicinal plants used by them for various diseases recorded orally by interviewing the elders, Vaidyas (doctors of that tribe by visiting their habitats called Thandas. Collected plants are stored in the Departmental Herbarium of Osmania College, Kurnool. Most of the medicinal plants are taken in as roots, tubers, stem and leaves, are taken orally with or without combination of other plants, external applications like paste, fumigation. Most of plants used by them are Herbs (42%, shrubs (20%, Trees (33%.and Climbers (5% The most striking feature of tribal life is their simplicity. The forest is able to provide them with everything. Professionally they are peasants, food-gatherers, hunters, small farmers, and, nomads. Sugalis use medicinal plants mainly for viral fevers, skin deceases, snake & scorpion bites and stomach problems. It is observed that the urban educated people are more aware of good effects of herbal medicine over allopathic medicine than the rural people. Due to the degraded forests and depleted resources, they are migrating to urban areas for livelihood. So there is a danger of losing knowledge of medicinal plants for human welfare. Hence there is an urgent need to document and popularize the value of herbal medicine among the rural people through Vana Samrakhak Samithi and other agencies.

    Keywords: Ehanobotany, Sugalis, Thandas, Yerramalais, Easteren ghats.

  10. Activity of medicinal plants from Ghana against the parasitic gut protist Blastocystis

    DEFF Research Database (Denmark)

    Bremer Christensen, Charlotte; Soelberg, Jens; Stensvold, Christen R; Jäger, Anna

    2015-01-01

    other flavourings. The aim of this study was to evaluate the anti-Blastocystis activity of 24 plant parts from 21 medicinal plants from Ghana. MATERIALS AND METHODS: The medicinal plants were collected in the Greater Accra region of Ghana. Every plant part was tested in three different extracts; an...... activity as the reference anti-protozoal drug MTZ. Historically, the active plants found in this study have been used against dysentery, diarrhoea or other stomach disorders. Nowadays they are not used specifically for dysentery, but they are being used as medicinal plants against various stomach disorders.......ETHNOPHARMACOLOGICAL RELEVANCE: The plants tested in this study were examples of plants historically used to treat or alleviate several types of stomach disorders manifested by e.g. stomachache, diarrhoea or dysentery. These plants have been consumed typically as a decoction, sometimes mixed with...

  11. Efficient micropropagation and assessment of genetic fidelity of Boerhaavia diffusa L- High trade medicinal plant.

    Science.gov (United States)

    Patil, Kapil S; Bhalsing, Sanjivani R

    2015-07-01

    Boerhaavia diffusa L is a medicinal herb with immense pharmaceutical significance. The plant is used by many herbalist, Ayurvedic and pharmaceutical industries for production biopharmaceuticals. It is among the 46 medicinal plant species in high trade sourced mainly from wastelands and generally found in temperate regions of the world. However, the commercial bulk of this plant shows genetic variations which are the main constraint to use this plant as medicinal ingredient and to obtain high value products of pharmaceutical interest from this plant. In this study, we have regenerated the plant of Boerhaavia diffusa L through nodal explants and evaluated genetic fidelity of the micropropagated plants of Boerhaavia diffusa L with the help of random amplified polymorphic DNA (RAPD) markers. The results obtained using RAPD showed monomorphic banding pattern revealing genetic stability among the mother plant and in vitro regenerated plants of Boerhaavia diffusa L. PMID:26261407

  12. ETHNO MEDICINAL SURVEY OF MEDICINAL PLANTS USED TO CURE WOUNDS IN DARIKAL GAON OF TEZPUR IN ASSAM, NORTH EAST INDIA

    Directory of Open Access Journals (Sweden)

    Das Amar Jyoti

    2012-02-01

    Full Text Available The people residing in Darikal gaon village in Tezpur of Assam mostly depend on the vegetation around them for the prevention as well as the treatment of diseases and ailments. The present ethnomedicinal survey was carried out in Darikal gaon village for the documentation of important medicinal plants used for wound healing. Ethnomedicinal information was gathered through questionnaire from the people of Darikal gaon (Tezpur in Assam of North east India. We have reported 19 species of medicinally important plants belonging to 16 families.

  13. STUDY OF PLANT BIODIVERSITY OF HAZARIBAG DISTRICT JHARKHAND INDIA AND ITS MEDICINAL USES

    Directory of Open Access Journals (Sweden)

    Hari Shankar Lal

    2012-01-01

    Full Text Available Jharkhand is rich in biodiversity of medicinal plants. The forest area is about 40% of the total area of Jharkhand. 32 tribal communities found in Jharkhand. They are used medicinal plants by traditional knowledge. Traditional medicinal practioners known as vaidays or kavirajas from the primary health care provider in rural Jharkhand.The objective of this present study was to conduct a value addition survey amongst tribal of Hazaribag and around the district of Jharkhand. Knowledge about to conserve these natural resources is very important. If all the people know about our natural resources & its important in our life by training or another sources than save it for value addition. If one sps save per people by conserve it for value addition than disease free nature obtained. Information on 95 plants sps was obtained which were used by tribal vaidyas to treat various ailments given the table 1. These medicinal plants belong to 95 genera and 51 families. All plants were grown or cultivated in home steads or fields as ornamental plant, shade giving plants ,timber yielding plants, home construction plants ,medicinal plants ,vegetable ,fruits etc.The various plant part used included whole plants, leaves ,stems,roots,tuber,barks,flower,fruits,&seeds. Traditional and ethnic knowledge generated from such leads has played most significant role in the discovery of novel product as well as newer ideas about conservation of natural resources. This paper deals the biodiversity of plant which is used by tribals in Hazaribag Jharkhand.

  14. Indigenous use and bio-efficacy of medicinal plants in the Rasuwa District, Central Nepal

    Directory of Open Access Journals (Sweden)

    Boon Emmanuel K

    2010-01-01

    Full Text Available Abstract Background By revealing historical and present plant use, ethnobotany contributes to drug discovery and socioeconomic development. Nepal is a natural storehouse of medicinal plants. Although several ethnobotanical studies were conducted in the country, many areas remain unexplored. Furthermore, few studies have compared indigenous plant use with reported phytochemical and pharmacological properties. Methods Ethnopharmacological data was collected in the Rasuwa district of Central Nepal by conducting interviews and focus group discussions with local people. The informant consensus factor (FIC was calculated in order to estimate use variability of medicinal plants. Bio-efficacy was assessed by comparing indigenous plant use with phytochemical and pharmacological properties determined from a review of the available literature. Criteria were used to identify high priority medicinal plant species. Results A total of 60 medicinal formulations from 56 plant species were documented. Medicinal plants were used to treat various diseases and disorders, with the highest number of species being used for gastro-intestinal problems, followed by fever and headache. Herbs were the primary source of medicinal plants (57% of the species, followed by trees (23%. The average FIC value for all ailment categories was 0.82, indicating a high level of informant agreement compared to similar studies conducted elsewhere. High FIC values were obtained for ophthalmological problems, tooth ache, kidney problems, and menstrual disorders, indicating that the species traditionally used to treat these ailments are worth searching for bioactive compounds: Astilbe rivularis, Berberis asiatica, Hippophae salicifolia, Juniperus recurva, and Swertia multicaulis. A 90% correspondence was found between local plant use and reported plant chemical composition and pharmacological properties for the 30 species for which information was available. Sixteen medicinal plants were ranked as priority species, 13 of which having also been prioritized in a country-wide governmental classification. Conclusions The Tamang people possess rich ethnopharmacological knowledge. This study allowed to identify many high value and high priority medicinal plant species, indicating high potential for economic development through sustainable collection and trade.

  15. Prospects and Challenges for Harnessing Opportunities in Medicinal Plants Sector in India

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    Harbir Singh

    2006-09-01

    Full Text Available The importance of the medicinal plants sector can be gauged from the fact that herbal medicines serve the healthcare needs of about 80 per cent of the world's population. India, with approximately eight percent of world's biodiversity including plant genetic diversity with medicinal properties, has the potential of becoming a major global player in market for medicinal plants-based herbal formulations and products. However, prior to establishment of Medicinal Plants Board, there was no nodal agency to look into medicinal plants as an economic 'sector' and different organisations dealt with different aspects of medicinal plants without any clear cut focus and coordination. This lack of co-ordination led to critical research gaps relating to socio-economic and policy aspects of medicinal plants. At the same time, absence of formal marketing linkages and effective buy-back arrangements hindered the development of medicinal plants sector. Developing appropriate varieties for cultivation which could ensure uniform quality and continuous supply of raw material for processing industry would not only meet the industry demand but also halt the degradation of natural resource base. To capitalize on expanding opportunities in the international market, we need to focus on scientific methods of cultivation, harvesting, processing, grading, transport, storage, labeling and marketing practices involved in the entire supply chain for medicinal plants. Policy and institutional issues particularly related to co-ordination among various stake holders are one of the major constraints faced by this sector. Species- specific and socio-economic environment specific research would be helpful for identification of an optimal institutional framework to take care of needs of various stakeholders and also cater to social needs without adverse implications for equity and environment.

  16. Medicinal plants - a potent antibacterial source against bacterial leaf blight (BLB) of rice

    International Nuclear Information System (INIS)

    The antibacterial potential of indigenous medicinal plants as alternative chemical pesticides for controlling bacterial leaf blight (BLB) of rice was investigated. Twenty-five different species of medicinal plants were collected from various sites in Pakistan. Decoctions of all medicinal plant species were screened by the disc plate diffusion method for testing the susceptibility of an aggressive isolate of Xanthomonas oryzae pv. oryzae (Xoo 105). Out of twenty five medicinal plants, Thuja orientalis (cone + leaves), Azadirachta indica (seeds + fruits), Amomum subulatum (fruits), Terminalia chebula (fruits), Terminalia bellirica (fruits), Anethum graveolens (fruits) and Ferula assa-foetida (fruits) decoctions showed significant activity. The efficacy of decoctions from six promising plants were further tested through detached leaf, glasshouse and field assays. A decoction of Terminalia chebula demonstrated the highest effectiveness in terms of regulating BLB in the plants both under laboratory and field conditions. Bioactive fractions of Terminalia chebula were purified, characterized and tentatively identified as allegic acid. (author)

  17. Traditional medicinal plants as anticancer agents from Chhattishgarh, India: An overview

    OpenAIRE

    Ritesh Jain; Sanmati K. Jain

    2011-01-01

    An attempt has been made to review some medicinal plants used for the prevention and treatment of cancer in Chhattisgarh. Information on the name of plants, family, parts used and method of preparation has been collected from Ethanobotanical literatures. Information collected has revealed 53 plants species that are used for treatment of cancer in Chhattisgarh. All these plants were further reviewed for scientific evidence, 33 plants out of 53 plants were found for possess anticancer,...

  18. Medicinal plants used by Tibetans in Shangri-la, Yunnan, China

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    Yang Chunyan

    2009-05-01

    Full Text Available Abstract Background Medicinal plants used by the local people in Xizang (Tibet have been investigated since the 1960s. The others out of Xizang, however, have been less understood, although they may be easily and strongly influenced by the various local herbal practices, diverse environments, local religious beliefs and different prevalent types of diseases. In 2006, two ethnobotanical surveys were organized in the county of Shangri-la, Yunnan Province, SW China, to document the traditional medicinal plants used by the Tibetan people. Methods After literature surveying, four local townships were selected to carry out the field investigation. Three local healers were interviewed as key informants. The methods of ethnobotany, anthropology and participatory rural appraisal (PRA were used in the field surveys. Plant taxonomic approach was adopted for voucher specimen identification. Results Sixty-eight medicinal plant species in 64 genera of 40 families were recorded and collected. Among them, 23 species were found to have medicinal values that have not been recorded in any existing Tibetan literatures before, and 31 species were recorded to have traditional prescriptions. Moreover, the traditional preparations of each species and some folk medicinal knowledge were recorded and analyzed. These traditional prescriptions, preparations, new medicinal plants and folk medicinal knowledge and principles were discovered and summarized by local traditional Tibetan healers through times of treatment practices, and were passed down from generation to generation. Conclusion As a part of the cultural diversity of Tibetan community, these traditional medicinal knowledge and experiences may provide data and information basis for the sustainable utilization and development of Tibetan medicine, and may contribute to the local economic development. However, for many reasons, they are disappearing gradually as time goes by. Our study showed that there were abundant traditional Tibetan medicinal prescriptions and using methods. It implies that more Tibetan medicinal plants and traditional knowledge can be discovered. Further research should be done to save the wealth of these traditional medicinal knowledge and experiences before they are dying out.

  19. Determination of metals in medicinal plants highly consumed in Brazil

    Scientific Electronic Library Online (English)

    Alexandre Soares, Leal; Guilherme, Prado; Tatiana Cristina Bomfim, Gomes; Fernanda Peixoto, Sepe; Ilza, Dalmázio.

    2013-09-01

    Full Text Available Neste trabalho, amostras de Boldo (Peumus boldus), Castanha da Índia (Aesculus hippocastanum), Chá Verde (Camelia sinensis), Erva Cidreira (Melissa officinalis), Espinheira Santa (Maytenus ilicifolia), Guaraná (Paullinia cupana), Maracujá (Passiflora sp.), Mulungu (Erythrina velutina), Sene (Cassia [...] angustifolia) e Valeriana (Valeriana officinalis) foram investigadas utilizando a técnica Análise por Ativação Neutrônica (AAN-k0), a fim de se determinar os teores de metais e outros elementos químicos contaminantes. Os resultados revelaram a presença de elementos não essenciais ao organismo humano. A diversidade de impurezas químicas encontradas, mesmo em níveis de baixa concentração, considerando o potencial de toxicidade crônica desses elementos, reforça a necessidade de melhorias na aplicação de boas práticas pelos produtores e comerciantes e a hipótese de falta de controle de qualidade nos produtos vegetais. Abstract in english In this work, samples of the medicinal plants: Boldo (Peumus boldus), Castanha da Índia (Aesculus hippocastanum), Chá Verde (Camelia sinensis), Erva Cidreira (Melissa officinalis), Espinheira Santa (Maytenus ilicifolia), Guaraná (Paullinia cupana), Maracujá (Passiflora sp.), Mulungu (Erythrina velut [...] ina), Sene (Cassia angustifolia) and Valeriana (Valeriana officinalis) were evaluated BY using the Neutron Activation Analysis technique (NAA- k0) in order to determine the levels of metals and other chemical contaminants. The results showed the presence of non essential elements to the human body. The diversity of chemical impurities found even at low concentration levels, considering the potential for chronic toxicity of these elements, reinforces the need to improve the implementation of good practices by growers and traders, and the hypothesis of lack of quality control in plant products.

  20. Characterization of cysteine proteases in Malian medicinal plants.

    Science.gov (United States)

    Bah, Sékou; Paulsen, Berit S; Diallo, Drissa; Johansen, Harald T

    2006-09-19

    Extracts form 10 different Malian medicinal plants with a traditional use against schistosomiasis were investigated for their possible content of proteolytic activity. The proteolytic activity was studied by measuring the hydrolysis of two synthetic peptide substrates Z-Ala-Ala-Asn-NHMec and Z-Phe-Arg-NHMec. Legumain- and papain-like activities were found in all tested crude extracts except those from Entada africana, with the papain-like activity being the strongest. Cissus quadrangularis, Securidaca longepedunculata and Stylosanthes erecta extracts showed high proteolytic activities towards both substrates. After gel filtration the proteolytic activity towards the substrate Z-Ala-Ala-Asn-NHMec in root extract of Securidaca longepedunculata appeared to have Mr of 30 and 97kDa, while the activity in extracts from Cissus quadrangularis was at 39kDa. Enzymatic activity cleaving the substrate Z-Phe-Arg-NHMec showed apparent Mr of 97 and 26kDa in extracts from roots and leaves of Securidaca longepedunculata, while in Cissus quadrangularis extracts the activity eluted at 39 and 20kDa, with the highest activity in the latter. All Z-Phe-Arg-NHMec activities were inhibited by E-64 but unaffected by PMSF. The legumain activity was unaffected by E-64 and PMSF. The SDS-PAGE analysis exhibited five distinct gelatinolytic bands for Cissus quadrangularis extracts (115, 59, 31, 22 and 20kDa), while two bands (59 and 30kDa) were detected in Securidaca longepedunculata extracts. The inhibition profile of the gelatinolytic bands and that of the hydrolysis of the synthetic substrates indicate the cysteine protease class of the proteolytic activities. Several cysteine protease activities with different molecular weights along with a strong variability of these activities between species as well as between plant parts from the same species were observed. PMID:16621376

  1. Efficacy of anise oil, dwarf-pine oil and chamomile oil against thymidine-kinase-positive and thymidine-kinase-negative herpesviruses.

    Science.gov (United States)

    Koch, Christine; Reichling, Jürgen; Kehm, Roland; Sharaf, Mona M; Zentgraf, Hanswalter; Schneele, Jürgen; Schnitzler, Paul

    2008-11-01

    The effect of anise oil, dwarf-pine oil and chamomile oil against different thymidine-kinase-positive (aciclovir-sensitive) and thymidine-kinase-negative (aciclovir-resistant) herpes simplex virus type 1 (HSV-1) strains was examined. Clinical HSV-1 isolates containing frameshift mutations in the thymidine kinase (TK) gene, an insertion or a deletion, yield a non-functional thymidine kinase enzyme resulting in phenotypical resistance against aciclovir. The inhibitory activity of three different essential oils against herpes simplex virus isolates was tested in-vitro using a plaque reduction assay. All essential oils exhibited high levels of antiviral activity against aciclovir-sensitive HSV strain KOS and aciclovir-resistant clinical HSV isolates as well as aciclovir-resistant strain Angelotti. At maximum noncytotoxic concentrations of the plant oils, plaque formation was significantly reduced by 96.6-99.9%, when herpesviruses were preincubated with drugs before attachment to host cells. No significant effect on viral infectivity could be achieved by adding these compounds during the replication phase. These results indicate that anise oil, dwarf-pine oil and chamomile oil affected the virus by interrupting adsorption of herpesviruses and in a different manner than aciclovir, which is effective after attachment inside the infected cells. Thus the investigated essential oils are capable of exerting a direct effect on HSV and might be useful in the treatment of drug-resistant viruses. Chamomile oil did not reveal any irritating potential on hen's egg chorioallantoic membrane, demonstrated the highest selectivity index among the oils tested and was highly active against clinically relevant aciclovir-resistant HSV-1 strains. PMID:18957177

  2. Antiviral Potential of Medicinal Plants of Balochistan: Studies Based on the Local Investigations

    Directory of Open Access Journals (Sweden)

    *1F. A. Sattar

    2013-12-01

    Full Text Available Medicinal plants have been extensively used contrary to various infectious and non-infectious maladies world wide. A plethora of medicinal plants of Balochistan region have exhibited potential antiviral activity against a number of infections. Among numerous other ailments, viral infections have denounced the humankind survival, distressing millions of people every year, causing disability and death. A plausible remedy for the viral infections from medicinal plants could be inferred through ethnopharmacological approach. The purpose of current study is an ethnopharmacological screening for antiviral medicinal plants that are being used traditionally by the local population for different types of viral infections in Pishin and Loralai areas of Balochistan. The study resulted 30 medicinal being used against viral infections in the region.

  3. Evidence-based Review of Medicinal Plants Used for the Treatment of Hemorrhoids

    Directory of Open Access Journals (Sweden)

    Mohammad Abdollahi

    2013-01-01

    Full Text Available Hemorrhoidal disease is a common problem which is usually not managed properly with pharmacologic interventions and will eventually require surgery. However, there are many medicinal plants that were successfully used for the treatment of hemorrhoids in the traditional and folk medicine of different countries. In this study, these medicinal plants have been reviewed and their mechanism of action and their major chemical constituents responsible for their activities have been assessed individually. Among various herbal medicines, Aesculus hippocastanum, Boswellia species, Cissus quadrangularis, Euphorbia prostrata, Juniperus species, Melastoma malabathricum, Myrtus communis and Verbascum species have got higher support from scientific evidence. These medicinal plants may exert their beneficial effects in hemorrhoids by their anti-inflammatory, analgesic and venotonic activities. Several chemical constituents were identified in these plants which may be responsible for their pharmacological activities, of which, flavonoids, terpenoids, triterpenes and tannins are the majors.

  4. Anti-pseudomona and Anti-bacilli Activity of Some Medicinal Plants of Iran

    OpenAIRE

    Gholam Hosein Shahidi Bonjar; Ashraf Karimi Nik; Mohammad Reza Heydari; Mohammad Hassan Ghasemzadeh; Parvin Rashid Farrokhi; Mahmood Reza Moein; Shahla Mansouri; Alireza Foroumadi

    2003-01-01

    The use of plants in treatment of burns, dermatophytes, and infectious diseases is common in traditional medicine of Iran. Based on ethno pharmacological and taxonomic information, antibacterial activities of methanol extracts of some medicinal plants of Iran were determined by In Vitro bioassays using agar diffusion-method against standard strains of Pseudomonas aeruginosa, P. fluorescens, Bacillus subtilis, B. cereus and B. pumilis at 20 mg/ml. From 180 plant species of 72 families, 78 spec...

  5. Ethnopharmacological survey of six medicinal plants from Mali, West-Africa

    OpenAIRE

    Bah Sekou; Ballo Ngolo; Skogsrud Mona; Glæserud Silje; Grønhaug Tom; Diallo Drissa; Paulsen Berit

    2008-01-01

    Abstract An ethnopharmacological survey was carried out to collect information about the use of six medicinal plants in the regions around Siby and Dioila, Mali. The plants investigated were Biopyhtum petersianum, Cola cordifolia, Combretum molle, Opilia celtidifolia, Parkia biglobosa and Ximenia americana. More than 60 medical indications were reported for the use of these plants in traditional medicine. The most frequently reported ailments were malaria (25.6%), different types of pain (14....

  6. An ethnobotanical survey of medicinal plants used in Terai forest of western Nepal

    OpenAIRE

    Singh Anant; Kumar Akhilesh; Tewari Divya

    2012-01-01

    Abstract Background Nepal Himalayas have been known as a rich source for valuable medicinal plants since Vedic periods. Present work is the documentation of indigenous knowledge on plant utilization as natural remedy by the inhabitants of terai forest in Western Nepal. Methods Study was conducted during 2010–2011 following standard ethnobotanical methods. Data about medicinal uses of plants were collected by questionnaire, personal interview and group discussion with pre identified informants...

  7. ETHNO BOTANICAL SURVEY OF MEDICINAL PLANTS IN KHAMMAM DISTRICT, ANDHRA PRADESH, INDIA

    OpenAIRE

    M. Bala Krishna; Mythili, S; K.Sravan Kumar; Ravinder, B.; Murali, T.; T.Mahender

    2011-01-01

    Ethnobotanical surveys were conducted in four different indigenous groups in Khammam District of Andhra Pradesh. The herbal practitioners in the study area were interviewed and information on medicinal plants was collected from the traditional healers called Vaidyars. This survey covers 96 medicinal plants belonging to 44 families that are used for the treatment of various diseases in a traditional way. Traditional approach was evaluated scientifically with some selected plant extracts to cur...

  8. Screening of antimutagenicity via antioxidant activity in Cuban medicinal plants.

    Science.gov (United States)

    Ramos, A; Visozo, A; Piloto, J; García, A; Rodríguez, C A; Rivero, R

    2003-08-01

    The reducing activity on the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, z.rad;OH radical scavenging potential, in vitro inhibition of lipid peroxidation and modulation of mutagenicity induced by ter-butyl hydroperoxide (TBH) in Escherichia coli were sequentially screened in 45 species of plants used with medicinal purposes in Cuba, in a search for antioxidant agents which protect DNA against oxidative stress.Five species, e.g. Tamarindus indica L., Lippia alba L., Pimenta dioica (L.) Merr, Rheedia aristata Griseb. and Curcuma longa L. displayed IC(50)<30 micro g/ml in the DPPH radical reduction assay and IC(50)<32 micro g/ml in lipid peroxidation inhibition testing. Pimenta dioica and Curcuma longa L. showed also a 20% inhibition of the in vitro induced z.rad;OH attack to deoxyglucose. Further antimutagenesis assay in Escherichia coli IC 188 evidenced that only Pimenta dioica prevents DNA damage by TBH to the test bacteria. A role of antioxidant enzymes is presumed in this case, as judged by a different response in the isogenic Escherichia coli IC 203 deficient in catalase and alkyl hydroperoxide reductase and the discrete inhibition of oxidative mutagenesis also observed when pre-treatment of the extract was assayed. Eugenol, the main constituent of the essential oil of Pimenta dioica, also inhibited oxidative mutagenesis by TBH in Escherichia coli, at concentrations ranging from 150 to 400 micro g/plate. PMID:12860316

  9. Natural and artificial radioactivity determination of some medicinal plants

    Energy Technology Data Exchange (ETDEWEB)

    Desideri, Donatella, E-mail: donatella.desideri@uniurb.i [Institute of General Chemistry, Urbino University ' Carlo Bo' , Piazza Rinascimento 6, 61029 Urbino (Italy); Meli, Maria Assunta; Roselli, Carla [Institute of General Chemistry, Urbino University ' Carlo Bo' , Piazza Rinascimento 6, 61029 Urbino (Italy)

    2010-09-15

    Several medicinal plants used in Italy were analysed to determine natural and artificial radioactivity in those parts (leaves, fruits, seeds, roots, peduncles, flowers, barks, berries, thallus) used generally as remedies. The radionuclides were determined by alpha ({sup 238}U, {sup 210}Po) and gamma ({sup 214}Pb-Bi, {sup 210}Pb, {sup 40}K and {sup 137}Cs) spectrometry. {sup 238}U ranged between <0.1 and 7.32 Bq kg{sub dry}{sup -1}; {sup 210}Po between <0.1 and 30.3 Bq kg{sub dry}{sup -1}; {sup 214}Pb-{sup 214}Bi between <0.3 and 16.6 Bq kg{sub dry}{sup -1}; {sup 210}Pb between <3 and 58.3 Bq kg{sub dry}{sup -1}; {sup 40}K between 66.2 and 3582.0 Bq kg{sub dry}{sup -1}; {sup 137}Cs between <0.3 and 10.7 Bq kg{sub dry}{sup -1}. The percentage of {sup 210}Po extraction in infusion and decoction was also determined; the arithmetical mean value of percentage of {sup 210}Po extraction resulted 20.7 {+-} 7.5.

  10. Screening of Algerian Medicinal Plants for Acetylcholinesterase Inhibitory Activity

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    H. Benamar

    2010-01-01

    Full Text Available The aim of this study was to evaluate acetylcholinesterase (AChE inhibitory activity and phytochemical profile of some Algerian medicinal plants. The bioautography on Thin-Layer Chromatography (TLC reveals 10 active aqueous extracts from a total of 77 extracts. Among them, aqueous extract of Pistacia lentiscus presents seven active spots. The Ellman’s colorimetric method shows that aqueous extract of Pistacia atlantica and P. lentiscus present a strong AChE inhibition. The chloroformic fraction obtained after liquid-liquid partition of Atriplex halimus roots aqueous extract, presents a strong AChE inhibition among all fractions tested with IC50 of 9.55 ?g mL-1. The quantitative dosage of total phenolic compounds and total flavonoids by colorimetric method shows that Osyris quadripartita and Pistacia atlantica are the richest in total phenolic compounds (438.99 and 407.68 mg g-1, respectively, a highest content on total flavonoids was detected in extract from Rosmarinus officinalis and Acacia raddiana (125.70 and 115.37 mg g-1, respectively.

  11. Commercial cultivation by farmers of medicinal plants in northern Bangladesh

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    A. Z. M. Manzoor Rashid

    2014-06-01

    Full Text Available Medicinal plants (MPs are an important component of non-timber forest products (NTFPs, which are traditionally used in healthcare and source of livelihood all over the world. In an over-populated country like Bangladesh, the pressure on natural forests is immense; thus the cultivation of MPs can significantly contribute towards improving the livelihood of poor people, reducing the pressure on natural forests and enhancing biological diversity. Notwithstanding the growing recognition of its importance and economic and ecological potential, there has been little research on MPs, especially the cultivation, management and marketing aspects, in Bangladesh. Based on extensive fieldwork in a northern district of Bangladesh, this study explores various aspects of the cultivation, management and marketing of MPs. How collective efforts have brought economic and social benefits to communities was also examined in this study. It assesses the major processes and elements of management, identifies key problems and challenges and indicates ways of maximizing the potential of this important sector. The issues covered in this research include: farmers ’ perceptions and experiences; existing research and policy-making processes related to the MP sector; constraining factors (such as lack of processing technology, inadequate transportation, logistics, financial and storage infrastructure, lack of institutional capacity; markets, finance and networking; land use; pattern of livelihood and value chain issue.

  12. Molecular genetic studies on some irradiated medicinal plants

    International Nuclear Information System (INIS)

    this thesis aimed to study the molecular characterization , the phylogenetic relationships among the four mentha and the three ocimum species and to get some species-specific markers. twenty-one RAPD and 10 ISSR primers were used which showed high polymorphism among the species and detected 150 molecular markers for these genotypes (100 using RAPD and 50 by ISSR-analyses). detection of the phylogenetic relationships based on the three studied systems (RAPD,ISSR and their combined analyses ) indicated that these techniques succeeded in separating the seven species into two main clusters of the two mentha and ocimum genera. SDS-protein patterns characterized the seven genotypes based on presence/ absence and staining intensities of 14 polypeptide bands into two main groups.the effect of four doses of gamma irradiation on eight active components of volatile oils and SDS-protein pattern of stems of mentha viridis indicated that low levels of gamma irradiation could improve the value of some active components of medicinal plants such as menthol in mentha viridis

  13. A study of trace elements in some medicinal plants

    International Nuclear Information System (INIS)

    Twenty one medicinal plants (herbal) have been investigated for major, minor and trace elements using the proton induced X-ray emission (PIXE) method. The samples were collected from the local market in Dhaka city and they were analysed by the thick-target external beam technique of the PIXE method. The samples were exposed to the proton beam as 1-mm thick pellet 0 f 7 mm dia. and irradiated with 2.0 MeV proton having 10 nA beam intensity. for 10-20 ?C irradiation, the concentration of 15 elements,K, Ca, Ti, Cr, Mn, Fe, Ni, Cu, Zn, As, Br, Rb, Sr, Zr and Pb were measured by comparison with calibration factors obtained from a curve constructed on the basis of the NBS orchard leaf standard (SRM-1571) irradiated under identical experimental condition. The concentration of K and Ca observed in the samples were in the range of 0.34-5.96% and .11-3.98% respectively. For Mn, Fe, Cu, Zn, Cr, As and Pb the concentration ranges were 4.1-1100, 60-7600, 1.1-276, 7-164, 1.2-48, 1.1-31, and 3.1-128 mg/kg respectively. Ti, Br, Rb, Sr and Zr were also determined with variable accuracy. The validity of the procedure was established by analysing a NIST standard (tomato leaf). The results obtained were in good agreement with the certified values. 17 refs.,3 tables, 3 figs

  14. Rediscovering Medicinal Plants' Potential with OMICS: Microsatellite Survey in Expressed Sequence Tags of Eleven Traditional Plants with Potent Antidiabetic Properties

    OpenAIRE

    Sahu, Jagajjit; Sen, Priyabrata; Choudhury, Manabendra Dutta; Dehury, Budheswar; Barooah, Madhumita; Modi, Mahendra Kumar; Talukdar, Anupam Das

    2014-01-01

    Herbal medicines and traditionally used medicinal plants present an untapped potential for novel molecular target discovery using systems science and OMICS biotechnology driven strategies. Since up to 40% of the world's poor people have no access to government health services, traditional and folk medicines are often the only therapeutics available to them. In this vein, North East (NE) India is recognized for its rich bioresources. As part of the Indo-Burma hotspot, it is regarded as an epic...

  15. Evaluation of the In Vitro Antiplasmodial, Antileishmanial, and Antitrypanosomal Activity of Medicinal Plants Used in Saudi and Yemeni Traditional Medicine

    OpenAIRE

    Mothana, Ramzi A.; Nawal M. Al-Musayeib; Al-Ajmi, Mohamed F.; Paul Cos; Louis Maes

    2014-01-01

    The antiplasmodial, antileishmanial, and antitrypanosomal activity of twenty-five medicinal plants distributed in Saudi Arabia and Yemen was evaluated. The plants were extracted with methanol and screened in vitro against erythrocytic schizonts of Plasmodium falciparum, intracellular amastigotes of Leishmania infantum and Trypanosoma cruzi, and free trypomastigotes of T. brucei. To assess selectivity, cytotoxicity was determined on MRC-5 cells. Criteria for activity were an IC50 < 10??g/mL an...

  16. ETHNO BOTANICAL SURVEY OF MEDICINAL PLANTS IN KHAMMAM DISTRICT, ANDHRA PRADESH, INDIA

    Directory of Open Access Journals (Sweden)

    M. Bala krishna

    2011-11-01

    Full Text Available Ethnobotanical surveys were conducted in four different indigenous groups in Khammam District of Andhra Pradesh. The herbal practitioners in the study area were interviewed and information on medicinal plants was collected from the traditional healers called Vaidyars. This survey covers 96 medicinal plants belonging to 44 families that are used for the treatment of various diseases in a traditional way. Traditional approach was evaluated scientifically with some selected plant extracts to cure many diseases. Several plant extracts like Gymnema sylvestre, Syzygium cumini, Tephrosia purpurea have proved their efficiency in treating many diseases like Diabetes mellitus and skin diseases. The present survey provides the information about various medicinal plants which were not recognized for their medicinal value. These plants are the natural remedies for treating many of the diseases This survey provided information about 96 plants with medicinal properties. This survey had been performed on the plants commonly used by the indigenous people for treating various diseases they had been encountering. All the information gathered from the indigenous people and the herbal practitioners helped to bring several medicinal plants to limelight which on further proceedings proves their therapeutic properties.

  17. Propagação vegetativa de liamba, planta medicinal Vegetative propagation of liamba, a medicinal plant

    Directory of Open Access Journals (Sweden)

    Maria de Fátima B Coelho

    2011-09-01

    Full Text Available A liamba (Vitex agnus castus L. é utilizada no Brasil como medicinal e apresenta compostos com estrutura química semelhante à progesterona. Visando avaliar a propagação vegetativa de liamba foram conduzidos dois experimentos. O primeiro, com estacas da parte aérea com 20 cm de comprimento, sem folhas e classificadas em dois grupos: apical e basal. As estacas tiveram a espessura padronizada em 3 a 5 mm de diâmetro e 40 unidades de cada tipo foram colocadas em sacolas de polietileno (10 x 30 cm preenchidas com o substrato solo + esterco na proporção volumétrica de 2:1. O segundo, com miniestacas da parte aérea da planta com 3 a 5 cm de comprimento, sem folhas e no delineamento experimental em blocos casualizados com quatro repetições de 20 miniestacas, no esquema fatorial 2 x 3. Os tratamentos foram tipo da miniestaca (com talão e sem talão e substrato (solo; solo + esterco bovino curtido e solo + composto. A propagação vegetativa de liamba pode ser feita por estacas basais ou mini-estacas com talão em substrato solo + composto.The liamba (Vitex agnus castus L. is used as a medicinal species in Brazil and presents compounds with similar chemical structure to progesterone. To evaluate the propagation of liamba two experiments were carried out. The first, using shoot cuttings with 20 cm long, leafless and classified into two groups, apical and basal. The cuttings were standardized in their thickness of 3 to 5 mm in diameter and 40 units of each type were placed in polyethylene bags (10 x 30 cm filled with soil + manure in the volumetric ratio of 2:1. The second, with shoot minicuttings of the plant canopy with 3 to 5 cm long, without leaves and in a randomized block experimental design with four replications of 20 minicuttings, in a factorial 2 x 3. The treatments were kind of mini-cuttings (with and without hell and substrate (soil, soil + cattle manure and soil + compost. The vegetative propagation of liamba can be made by basal cuttings or minicuttings with heel in soil + compost.

  18. Somatic embryogenesis and plant regeneration in Wedelia calendulacea Less. an endangered medicinal plant

    Scientific Electronic Library Online (English)

    Shamima Akhtar, Sharmin; Md. Jahangir, Alam; Md. Mominul Islam, Sheikh; Kanak Kanti, Sarker; Muhammad, Khalekuzzaman; Md. Anwarul, Haque; Mohammad Firoz, Alam; Iftekhar, Alam.

    2014-06-01

    Full Text Available In this work, plant regeneration via somatic embryogenesis was achieved from leaf and internode derived callus of Wedelia calendulacea, an endangered medicinal plant. Primary callus was induced by culturing leaf disc and internode explant on Murashige and Skoog medium supplemented with 2.0 mg L-1 of [...] 2,4-D under light condition. Transfer of embryogenic callus on a reduced concentration of 2,4-D facilitated somatic embryo development while calluses remained unorganized at the same 2,4-D level. A histological analysis confirmed somatic embryo by revealing the presence of a closed vascular system in the developing embryos and lack of a vascularconnection with surrounding callus tissues. Somatic embryos germinated into plantlets upon transfer on MS medium containing 1.0 mg L-1 BAP plus 0.5 mg L-1 GA3. Plantlets were acclimatized successfully and survived under soil condition. This is the first on somatic embryogenesis of W.calendulacea. This result could facilitate genetic transformation of this important medicinal plant.

  19. The use of phylogeny to interpret cross-cultural patterns in plant use and guide medicinal plant discovery

    DEFF Research Database (Denmark)

    Saslis-Lagoudakis, C Haris; Klitgaard, Bente B; Forest, Félix; Francis, Louise; Savolainen, Vincent; Williamson, Elizabeth M; Hawkins, Julie A; Saslis Lagoudakis, Haris

    2011-01-01

    BACKGROUND: The study of traditional knowledge of medicinal plants has led to discoveries that have helped combat diseases and improve healthcare. However, the development of quantitative measures that can assist our quest for new medicinal plants has not greatly advanced in recent years....... Phylogenetic tools have entered many scientific fields in the last two decades to provide explanatory power, but have been overlooked in ethnomedicinal studies. Several studies show that medicinal properties are not randomly distributed in plant phylogenies, suggesting that phylogeny shapes ethnobotanical use....... Nevertheless, empirical studies that explicitly combine ethnobotanical and phylogenetic information are scarce. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we borrowed tools from community ecology phylogenetics to quantify significance of phylogenetic signal in medicinal properties in plants and identify...

  20. Sustainable harvest of medicinal plants at Bulashbar Nullah, Astore (Northern Pakistan).

    Science.gov (United States)

    Shinwari, Zabta Khan; Gilani, Syed Shahinshah

    2003-02-01

    Rapid decline of plant resources due to their conventional use needs ex-situ and in-situ conservation, training of the community regarding collection of medicinal plants and their marketing. In this regard, the Bulashbar valley, Astore, District Diamer was identified as a case study. The main objectives of this activity were to enlist economic, medicinal and aromatic plants including their occurrence, general distribution and abundance in the project areas; to determine traditional use and pharmaceutical values of each medicinal plant species found in the project area. Ethnobotanical studies of the area revealed that 33 plants were being used by the local communities for medicinal purposes. Two species, Bunium persicum and Ephedra gerardiana, are recommended for in vitro cultivation to obtain quick benefits. While Hippophae rhamnoides can be sustainably used for socio-economic uplift of the local communities. PMID:12648828

  1. Levels of trace elements in medicinal plants with anti-diabetic potential

    International Nuclear Information System (INIS)

    Medicinal plants with anti-diabetic potential have been characterized by Particle-Induced X-ray Emission (PIXE) technique. Trace elements such as Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Rb, Sr and Pb are found to be present in these studied medicinal plant samples. The concentrations of elements like K and Ca are quantified in percentage level whereas other elements are found to be in parts per million levels. Elemental analysis of ten different medicinal plant samples commonly used for management and cure of diabetes, shows variation in concentrations. These elements either directly or indirectly may play some role to control diabetes. (author)

  2. An ethnobotanical survey of medicinal plants used in the eastern highlands of Papua New Guinea

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    Jorim Ronald Y

    2012-12-01

    Full Text Available Abstract Background The Eastern Highlands area of Papua New Guinea (PNG has a rich tradition of medicinal plant use. However, rapid modernization is resulting in the loss of independent language traditions and consequently a loss of individuals knowledgeable in medicinal plant use. This report represents a program to document and preserve traditional knowledge concerning medicinal plant use in PNG. This report documents and compares traditional plant use in the Eastern Highlands districts of Unggai-Bena, Okapa, and Obura-Wonenara, and puts these new records in context of previously documented PNG medicinal plant use. Methods This manuscript is an annotated combination of Traditional Medicines survey reports generated by UPNG trainees using a survey questionnaire titled “Information sheet on traditional herbal reparations and medicinal plants of PNG”. The Traditional Medicines survey project is supported by WHO, US NIH and PNG governmental health care initiatives and funding. Results Overall, after “poisoning” (synonymous with “magic” the most commonly recorded ailments addressed by medicinal plant use were pain, gynecological disease, gastrointestinal maladies, anemia or malnutrition and malaria. However, the recorded indications for plant use varied widely amongst the different survey locations. Unlike many areas of PNG, mixing of ingredients was the most common mode of preparation recorded, except for two areas where the consumption of fresh plant material was more common. Throughout the Eastern Highlands oral administration was most common, with topical application second. Overall, leaves were most commonly used in the preparations of the healers interviewed, followed by bark and stems. Several new medicinal uses of plants were also documented. Conclusions Collaboration between the WHO, UPNG and the PNG Department of Health initiated Traditional Medicine survey program in order to preserve traditional knowledge concerning medicinal plant use in PNG. This effort promotes integration of effective and accessible traditional practices with Western protocols. The Traditional Medicine surveys are particularly important because, in the absence of the clinical validation, the documentation of the consistent use of a given plant for specific indication by a large number of herbalists, across a wide range of ethnic traditions, maybe considered as a positive criterion for the promulgation of said use amongst PNG’s recently formed traditional healer associations.

  3. Alpha-Glucosidase Enzyme Biosensor for the Electrochemical Measurement of Antidiabetic Potential of Medicinal Plants.

    Science.gov (United States)

    Mohiuddin, M; Arbain, D; Islam, A K M Shafiqul; Ahmad, M S; Ahmad, M N

    2016-12-01

    A biosensor for measuring the antidiabetic potential of medicinal plants was developed by covalent immobilization of ?-glucosidase (AG) enzyme onto amine-functionalized multi-walled carbon nanotubes (MWCNTs-NH2). The immobilized enzyme was entrapped in freeze-thawed polyvinyl alcohol (PVA) together with p-nitrophenyl-?-D-glucopyranoside (PNPG) on the screen-printed carbon electrode at low pH to prevent the premature reaction between PNPG and AG enzyme. The enzymatic reaction within the biosensor is inhibited by bioactive compounds in the medicinal plant extracts. The capability of medicinal plants to inhibit the AG enzyme on the electrode correlates to the potential of the medicinal plants to inhibit the production of glucose from the carbohydrate in the human body. Thus, the inhibition indicates the antidiabetic potential of the medicinal plants. The performance of the biosensor was evaluated to measure the antidiabetic potential of three medicinal plants such as Tebengau (Ehretis laevis), Cemumar (Micromelum pubescens), and Kedondong (Spondias dulcis) and acarbose (commercial antidiabetic drug) via cyclic voltammetry, amperometry, and spectrophotometry. The cyclic voltammetry (CV) response for the inhibition of the AG enzyme activity by Tebengau plant extracts showed a linear relation in the range from 0.423-8.29 ?A, and the inhibition detection limit was 0.253 ?A. The biosensor exhibited good sensitivity (0.422 ?A/mg Tebengau plant extracts) and rapid response (22 s). The biosensor retains approximately 82.16 % of its initial activity even after 30 days of storage at 4 °C. PMID:26887579

  4. Ethnobotanical investigation of traditional medicinal plants commercialized in the markets of Mashhad, Iran

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    Mohammad Sadegh Amiri

    2013-05-01

    Full Text Available Objective: An ethnobotanical survey on the medicinal plant species marketed in Mashhad city, northeastern Iran, was conducted in order to document traditional medicinal knowledge and application of medicinal plants. Materials and Methods: This study was undertaken between 2011 and 2012. The indigenous knowledge of traditional healers used for medicinal purposes were collected through questionnaire and personal interviews during field trips. Ethnobotanical data was arranged alphabetically by family name followed by botanical name, vernacular name, part used, folk use, and recipe. Correct identification was made with the help of the various Floras and different herbal literature at the Ferdowsi University of Mashhad Herbarium (FUMH. Results: The present investigation reported medicinal information for about 269 species, belonging to 87 vascular plant families and one fungus family. The most important family was Lamiaceae with 26 species, followed by Asteraceae with 23, Fabaceae with 20, and Apiaceae with 19. Herbal medicine uses reported by herbalists was classified into 132 different uses which show significant results to treat a wide spectrum of human ailments. Plants sold at the market were mostly used for digestive system disorders, respiratory problems, urological troubles, nervous system disorders, skin problems, and gynecological ailments. Conclusion: This survey showed that although people in study area have access to modern medical facilities,  a lot of them still continue to depend on medicinal plants for the treatment of healthcare problems. The present paper represents significant ethnobotanical information on medical plants which provides baseline data for future pharmacological and phytochemical studies.

  5. Root endophyte Piriformospora indica DSM 11827 alters plant morphology, enhances biomass and antioxidant activity of medicinal plant Bacopa monniera.

    Science.gov (United States)

    Prasad, Ram; Kamal, Shwet; Sharma, Pradeep K; Oelmüller, Ralf; Varma, Ajit

    2013-12-01

    Unorganized collections and over exploitation of naturally occurring medicinal plant Bacopa monniera is leading to rapid depletion of germplasm and is posing a great threat to its survival in natural habitats. The species has already been listed in the list of highly threatened plants of India. This calls for micropropagation based multiplication of potential accessions and understanding of their mycorrhizal associations for obtaining plants with enhanced secondary metabolite contents. The co-cultivation of B. monniera with axenically cultivated root endophyte Piriformospora indica resulted in growth promotion, increase in bacoside content, antioxidant activity and nuclear hypertrophy of this medicinal plant. PMID:23681554

  6. The use of medicinal plants in the trans-himalayan arid zone of Mustang district, Nepal

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    Chaudhary Ram P

    2010-04-01

    Full Text Available Abstract Background This study documents the use of medicinal plants from the Mustang district of the north-central part of Nepal. Traditional botanical medicine is the primary mode of healthcare for most of the population of this district and traditional Tibetan doctors (Amchi serve as the local medical experts. Methods Field research was conducted in 27 communities of the Mustang district in Nepal from 2005-2007. We sampled 202 interviewees, using random and snowball sampling techniques. After obtaining prior informed consent, we collected data through semi-structured interviews and participant-observation techniques. Voucher specimens of all cited botanic species were deposited at TUCH in Nepal. Results We recorded the traditional uses of 121 medicinal plant species, belonging to 49 vascular plant and 2 fungal families encompassing 92 genera. These 121 species are employed to treat a total of 116 ailments. We present data on 58 plant species previously unknown for their medicinal uses in the Mustang district. Of the medicinal plants reported, the most common growth form was herbs (73% followed by shrubs, trees, and climbers. We document that several parts of individual plant species are used as medicine. Plant parts were generally prepared using hot or cold water as the 'solvent', but occasionally remedies were prepared with milk, honey, jaggery, ghee and oil. Amchis recommended different types of medicine including paste, powder, decoction, tablet, pills, infusion, and others through oral, topical, nasal and others routes of administration. Conclusions The traditional pharmacopoeia of the Mustang district incorporates a myriad of diverse botanical flora. Traditional knowledge of the remedies is passed down through oral traditions and dedicated apprenticeships under the tutelage of senior Amchi. Although medicinal plants still play a pivotal role in the primary healthcare of the local people of Mustang, efforts to ensure the conservation and sustainable use of medicinal species are necessary.

  7. Powerful hepatoprotective and hepatotoxic plant oligostilbenes, isolated from the Oriental medicinal plant Vitis coignetiae (Vitaceae).

    Science.gov (United States)

    Oshima, Y; Namao, K; Kamijou, A; Matsuoka, S; Nakano, M; Terao, K; Ohizumi, Y

    1995-01-15

    The methanol extract of the Oriental medicinal plant Vitis coignetiae (Vitaceae) showed hepatoprotective activity in the in vitro assay method using primary cultured rat hepatocytes. Activity-guided fractionation of the extract afforded epsilon-viniferin as an active principle. The protective effect of epsilon-viniferin against mice carbon tetrachloride-induced hepatic injury in mice was shown by serum enzyme assay as well as by pathological examination. In addition to epsilon-viniferin, plant oligostilbenes, ampelopsins A, C, F and the mixture of vitisin A and cis-vitisin A were also present in the extract. Among them, ampelopsin C and the mixture of vitisin A and cis-vitisin A were found to be powerful hepatotoxins. PMID:7843333

  8. Antioxidant and acetylcholinesterase-inhibitory properties of long-term stored medicinal plants

    Directory of Open Access Journals (Sweden)

    Amoo Stephen O

    2012-07-01

    Full Text Available Abstract Background Medicinal plants are possible sources for future novel antioxidant compounds in food and pharmaceutical formulations. Recent attention on medicinal plants emanates from their long historical utilisation in folk medicine as well as their prophylactic properties. However, there is a dearth of scientific data on the efficacy and stability of the bioactive chemical constituents in medicinal plants after prolonged storage. This is a frequent problem in African Traditional Medicine. Methods The phytochemical, antioxidant and acetylcholinesterase-inhibitory properties of 21 medicinal plants were evaluated after long-term storage of 12 or 16 years using standard in vitro methods in comparison to freshly harvested materials. Results The total phenolic content of Artemisia afra, Clausena anisata, Cussonia spicata, Leonotis intermedia and Spirostachys africana were significantly higher in stored compared to fresh materials. The flavonoid content were also significantly higher in stored A. afra, C. anisata, C. spicata, L. intermedia, Olea europea and Tetradenia riparia materials. With the exception of Ekebergia capensis and L. intermedia, there were no significant differences between the antioxidant activities of stored and fresh plant materials as measured in the ?-carotene-linoleic acid model system. Similarly, the EC50 values based on the 2,2-diphenyl-1-picrylhydrazyl (DPPH free radical scavenging assay were generally lower for stored than fresh material. Percentage inhibition of acetylcholinesterase was generally similar for both stored and fresh plant material. Stored plant material of Tetradenia riparia and Trichilia dregeana exhibited significantly higher AChE inhibition than the fresh material. Conclusions The current study presents evidence that medicinal plants can retain their biological activity after prolonged storage under dark conditions at room temperature. The high antioxidant activities of stable bioactive compounds in these medicinal plants offer interesting prospects for the identification of novel principles for application in food and pharmaceutical formulations.

  9. Comparative evaluation of dietary oregano, anise and olive leaves in laying Japanese quails

    Directory of Open Access Journals (Sweden)

    EV Christaki

    2011-06-01

    Full Text Available Aim of the present study was the comparative evaluation of the effect of ground oregano, anise and olive leaves as feed additives on performance and some egg quality characteristics of laying Japanese quails. A total of 189 Coturnix japonica quails (126 females and 63 males, 149 days old, were randomly allocated into seven equal groups with three subgroups of 9 birds each (6 females and 3 males. A commercial laying diet was fed to the control group. The remaining six groups were fed the same diet supplemented with oregano at 10 g/kg or 20 g/kg, anise at 10 g/kg or 20 g/kg and olive leaves at 10 g/kg or at 20 g/kg. The birds were offered feed and water ad libitum for a period of 29 days, while being kept under commercial conditions. During the experiment, egg production, feed intake and mortality were recorded daily. At the end of the feeding period egg weight, egg yolk, albumen and eggshell weight percentages, egg yolk color (using the L*a*b* color space and blood serum triglycerides were determined. The diets supplemented with olive leaves (10 g/kg or 20 g/kg resulted in a tendency (p = 0.054 for higher egg production percentage. Also, the color parameter a* was significantly (p = 0.001 higher in the eggs of quails that consumed oregano (10g/kg or 20 g/kg or olive leaves (10g/kg or 20 g/kg.

  10. Comparative evaluation of dietary oregano, anise and olive leaves in laying Japanese quails

    Scientific Electronic Library Online (English)

    EV, Christaki; EM, Bonos; PC, Florou-Paneri.

    2011-06-01

    Full Text Available Aim of the present study was the comparative evaluation of the effect of ground oregano, anise and olive leaves as feed additives on performance and some egg quality characteristics of laying Japanese quails. A total of 189 Coturnix japonica quails (126 females and 63 males), 149 days old, were rand [...] omly allocated into seven equal groups with three subgroups of 9 birds each (6 females and 3 males). A commercial laying diet was fed to the control group. The remaining six groups were fed the same diet supplemented with oregano at 10 g/kg or 20 g/kg, anise at 10 g/kg or 20 g/kg and olive leaves at 10 g/kg or at 20 g/kg. The birds were offered feed and water ad libitum for a period of 29 days, while being kept under commercial conditions. During the experiment, egg production, feed intake and mortality were recorded daily. At the end of the feeding period egg weight, egg yolk, albumen and eggshell weight percentages, egg yolk color (using the L*a*b* color space) and blood serum triglycerides were determined. The diets supplemented with olive leaves (10 g/kg or 20 g/kg) resulted in a tendency (p = 0.054) for higher egg production percentage. Also, the color parameter a* was significantly (p = 0.001) higher in the eggs of quails that consumed oregano (10g/kg or 20 g/kg) or olive leaves (10g/kg or 20 g/kg).

  11. Pharmacokinetic profile of phytoconstituent(s) isolated from medicinal plants-A comprehensive review.

    Science.gov (United States)

    Mehta, Piyush; Shah, Rishi; Lohidasan, Sathiyanarayanan; Mahadik, K R

    2015-10-01

    Herbal medicine, the backbone of traditional medicine, has played an important role in human health and welfare for a long period. Traditional therapeutic approaches of regional significance are found in Africa, South and Central America, China, India, Tibet, Indonesia, and the Pacific Islands. The considerable scientific significance and commercial potential of traditional medicines have resulted in increased international attention and global market demands for herbal medicines, especially Chinese herbal medicines. Herbal medicines currently are the primary form of health care for the poor in the developing countries, and also are widely used as a supplement or substitute for conventional drugs in developed countries. These traditional medicines have a pivotal role in the treatment of various ailments and more than 50% of drugs used in Western pharmacopoeia are isolated from herbs or derived from modifications of chemicals found in plants. Herbal medicines usually contain a complex mixture of various bioactive molecules, which make its standardization complicated, and there is little information about all compounds responsible for pharmacological activity. Several research papers have been published that claim pharmacological activity of herbal medicines but few are discussing the role of the exact phytoconstituent. Understanding the pharmacokinetic profile of such phytoconstituents is essential. Although there are research papers that deal with pharmacokinetic properties of phytoconstituents, there are a number of phytoconstituents yet to be explored for their kinetic properties. This article reviews the pharmacokinetic profile of 50 different therapeutically effective traditional medicinal plants from the year 2003 onward. PMID:26587392

  12. In vitro anti-leukemic and antiviral activities of traditionally used medicinal plants in Taiwan.

    Science.gov (United States)

    Chiang, Lien-Chai; Cheng, Hua-Yew; Chen, Chi-Chain; Lin, Chun-Ching

    2004-01-01

    Medicinal plants have been historically used as treatment for different kinds of human diseases. In this study, hot water (HW) extract of five Taiwanese traditionally used medicinal plants was evaluated for their in vitro anti-leukemic (including anti-K562, L1210, P3HR1, Raji and U937 leukemia cells) and antiviral (including HSV-1 and HSV-2) activities. Results showed that Blumea lacera exhibited broad anti-leukemic activity at magnitudes ranging from moderate to mild and Ixeris chinensis is effective at inhibiting the proliferation of K562 cells. B. lacera and Tithonia diversifolia suppressed the replication of HSV-1 and HSV-2, and had IC50 values below 100 microg/ml. The medicinal plants showed no cytotoxic effect at concentrations that inhibited HSV infection. It was, therefore, concluded that the HW extract of tested medicinal plants exhibited anti-leukemic and antiviral activities at different magnitudes of potency. PMID:15633805

  13. TRADITIONAL USES OF MEDICINAL PLANTS IN TREATING SKIN DISEASES IN NAGAPATTINAM DISTRICT OF TAMILNADU, INDIA

    Directory of Open Access Journals (Sweden)

    R.Sivaranjani

    2012-05-01

    Full Text Available The present documented the traditional knowledge of Medicinal Plants species used in various type of skin diseases in Nagapattinam district. We have documented the use of 50 species belonging to 26 families. The information on plants used as traditional medicine against skin diseases was gathered and ethnomedicinal survey based on interviews with local people involved in traditional herbal medicine practices. The particulars plants are used to cure variety of skin diseases, like swelling, wound healing, psoriasis, scabies, eczema, dandruff, tinea versicularis, tinea cruris, impetigo, skin parasities, leucoderma, leucoderma, leprosy, rash, etc. the studies carried out for the time in this area, the medicinal plants used by traditional users of N agapattinam district were arranged by botanical name, family, local name, habit, mode of preparation and uses.

  14. Evaluation of Phytochemical Constituents of Indian Medicinal Plant Hydnocarpus alpina WIGHT.

    OpenAIRE

    M. Dhanasekaran*, S. Karuppusamy, M. Annadurai, K.M.Rajasekaran

    2013-01-01

    Hydnocarpus alpina WIGHT. is a evergreen forest plant. It is an endemic plant to western ghats of India. Severallocal names are available based on distribution among the state in india that is Torathi (kanada), Maravetti(Malayalam), attuchankalai (tamil), kastel (hindi). This tree has very appreciated value in the aspect of medicine. Ithas anti-larvicidal, anti-feedant, anti-microbial and etc. It has the medicinal properties due to the presence of itssignificant chemical constituents. In this...

  15. ETHNO MEDICINAL STUDY OF THREATENED PLANTS OF SONITPUR DISTRICT IN ASSAM, NORTH EAST INDIA

    OpenAIRE

    Das Amar Jyoti; Kumar Rajesh; Athar Mohammad; Rawat Devendra Singh; Kumar Manoj; Khan Mohd Aqueel; Prakash Jai

    2013-01-01

    Assam is endowed with a rich wealth of medicinal plants. It has the richest reservoir of plant diversity of India and is one of the hot diversity spots of the world supporting about 50% of India’s biodiversity. Traditional medical practice has been recognized by the World health Organization (WHO) as a building block of primary healthcare. Assam has a rich traditional knowledge of folk medicinal practices. But rapid fragmentation of natural habitats and unrestricted exploitation coupled with ...

  16. Medicinal Plants and Ethnomedicine in Peril: A Case Study from Nepal Himalaya

    OpenAIRE

    Kunwar, Ripu M.; Mina Lamichhane Pandey; Laxmi Mahat Kunwar; Ananta Bhandari

    2014-01-01

    The impacts of climate change were severe on indigenous medicinal plant species and their dependent communities. The harvesting calendar and picking sites of these species were no longer coinciding and the changes were affecting harvesters' and cultivators' abilities to collect and use those species. Secondary sites: road-heads, wastelands, regenerated forests, and so forth, were being prioritized for collection and the nonindigenous medicinal plant species were being increasingly introduced ...

  17. The correlation of metal content in medicinal plants and their water extracts

    OpenAIRE

    Ran?elovi? Saša S.; Kosti? Danijela A.; Zarubica Aleksandra R; Miti? Snežana S.; Miti? Milan N.

    2013-01-01

    The quality of some medicinal plants and their water extracts from South East Serbia is determined on the basis of metal content using atomic absorption spectrometry. The two methods were used for the preparation of water extracts, to examine the impact of the preparation on the content of metals in them. Content of investigated metals in both water extracts is markedly lower then in medicinal plants, but were higher in water extract prepared by method (I), with exception of lead conten...

  18. Ethno Veterinary Medicinal Uses of Plants from Samahni Valley Dist. Bhimber, (Azad Kashmir) Pakistan

    OpenAIRE

    Muhammad Ishtiaq Ch; Khan, M.A.; Wajahat Hanif

    2006-01-01

    This study comprises of an ethnoveterinary report of medicinal plants of Samahni valley. It provides folk medicinal uses of plants used for treatment of various diseases of domestic animals. Among these important traditional knowledge is as; Albizzia lebbeck is used to treat chronic diarrhoea, dysentery and snake bite, Abutilon theophrasti in ephemeral fever, Bauhania variegata in severe constipation, Butea monosperma, Linum usitatissimum and Taraxacum officinale as tonic to enhance milk and ...

  19. Plantas medicinais: a necessidade de estudos multidisciplinares Medicinal plants: the need for multidisciplinary scientific studies

    OpenAIRE

    Maria Aparecida M. Maciel; Angelo C. Pinto; Valdir F. Veiga Jr; Noema F. Grynberg; Aurea Echevarria

    2002-01-01

    This paper presents a program emphasizing ethnopharmacological approaches that could allow great success in the study of medicinal plants. The minimum ethnopharmacological research team should consist of a botanist, a chemist and a pharmacologist with each carrying the responsibility for answering in sequential fashion critical questions. The chemical composition and pharmacological properties of the very efficient medicinal plant Croton cajucara were investigated according to ethnopharmacolo...

  20. Medicinal plants used by the Yi ethnic group: a case study in central Yunnan

    OpenAIRE

    Li Sumei; Long Chunlin; Long Bo; Shi Yana; Liu Benxi

    2009-01-01

    Abstract Background This paper is based on ethnomedicinal investigation conducted from 1999–2002 in Chuxiong, central Yunnan Province, Southwest China. The Yi medicine has made a great contribution to the ethnomedicinal field in China. Neither case studies nor integrated inventories have previously been conducted to investigate the traditional Yi plants. This paper aims to argue the status and features of medicinal plants used in traditional Yi societies through a case study. Methods The appr...

  1. Antineoplastic Screening of Some Medicinal Plants Against Ehrlich Ascites Carcinoma in Mice

    OpenAIRE

    A. Y. K. M. Masud Rana; J.A. Khanam; M. Asad-Ud-Daula

    2004-01-01

    Swiss Albino mice inoculated with Ehrlich ascites carcinoma cells were treated with the extract of some medicinal plants include Citrullus colocynthis, Withania somnifera, Bambusa arundinacea, Mesua ferrea, Acorus calamus, Myrica nagi, Calotropis procera, Catharanthus roseus, Ficus racemosa and also with clinically highly effective drug bleomycin. Among the medicinal plants Bambusa arundinacea showed highest cell growth inhibition 81.9%. The tumor cell growth inhibition were found to b...

  2. Antibacterial effects of medicinal plant extracts against Lactococcus garvieae, the etiological agent of rainbow trout lactococcosis

    OpenAIRE

    Mohammad Saeid Fereidouni; Mostafa Akhlaghi; Aliasghar Khadem Alhosseini

    2013-01-01

    Eight medicinal plants were assessed for antimicrobial activity against Lactococcus garvieae isolate obtained from diseased Oncorhynchus mykiss collected from rainbow trout fish farms in Iran. Lactococcus garvieae is among the major pathogens of a large number of fish species cultured in fresh and marine recirculating and net pen production systems. The antibacterial activity of the medicinal plants against L. garvieae was evaluated using disc diffusion, well diffusion and minimum inhibitory ...

  3. Evaluation of Antimicrobial Activity of the Methanol Extracts from 8 Traditional Medicinal Plants

    OpenAIRE

    Kang, Chang-Geun; Hah, Dae-Sik; Kim, Chung-Hui; Kim, Young-Hwan; Kim, Euikyung; Kim, Jong-Shu

    2011-01-01

    The methanol extract of 12 medicinal plants were evaluated for its antibacterial activity against Gram-positive (5 strains) and Gram-negative bacteria (10 strains) by assay for minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) . The antibacterial activity was determined by an agar dilution method (according to the guidelines of Clinical and Laboratory Standard Institute) . All the compounds (12 extracts) of the 8 medicinal plants (leaf or root) were active again...

  4. MOLECULAR MARKER STUDIES OF SELECTED MEDICINAL PLANTS FOR ASSESSMENT OF GENETIC DIVERSITY

    OpenAIRE

    Rajalakshmi, A.; N. KRITHIGA; A. Jayachitra

    2014-01-01

    Objective: The aim of this study is to examine the total antioxidant activity and Genetic relationships between six different medicinal plants were analysed. Method: The total antioxidant were analysed by using DPPH Photometric assay. The genomic DNA and RAPD Work were analyzed in selected medicinal plan using standard method. Mathwork software was used to draw the dendogram. Result: The results observed in the present study are Out of the 5 selected plants showed high antioxidant activ...

  5. Aloe Vera: The Miracle Plant Its Medicinal and Traditional Uses in India

    OpenAIRE

    Rajeswari, R.; M.Umadevi; C. Sharmila Rahale; Pushpa, R; S. Selvavenkadesh; K.P.Sampath Kumar; Debjit Bhowmik

    2012-01-01

    Aloe vera is the oldest medicinal plant ever known and the most applied medicinal plant worldwide. Extracts of Aloe Vera is a proven skin healer. Aloe Vera help to soothe skin injuries affected by burning, skin irritations, cuts and insect bites, and its bactericidal properties relieve itching and skin swellings. It is known to help slow down the appearance of wrinkles and actively repair the damaged skin cells that cause the visible signs of aging. Aloe is a powerfuldetoxifier, antiseptic an...

  6. Human health sciences—From cultivation to utilization of medicinal plants

    OpenAIRE

    Satoru Tsukagoshi; Megumi Sumino; Maya Kaneko; Yan Wang; Fumio Ikegami

    2012-01-01

    The aim of this review is to recognize the ability of plants used as food and medicine for our health care. From this point of view, we have studied economical production techniques of medicinal plants and vegetables that have physiological functions such as disease prevention, health maintenance and improvement of physical function. We revealed the suitable cultivation techniques such as the long-term freezing seed storage, and systematic and efficient seedling production of Swertia...

  7. Antiproliferative effects of some medicinal plants on HeLa cells

    OpenAIRE

    Ceni?-Miloševi? Desanka; Tambur Z.; Bokonji? D.; Ivan?aji? S.; Stanojkovi? Tatjana; Grozdani? Nadja; Jurani? Zorica

    2013-01-01

    Medicinal plants maintain the health and vitality of individuals, and also have potential curative effect on various diseases, including cancer. In this study were investigated the antiproliferative effects of water extracts of previously obtained ethanolic dry extracts of three different medicinal plants (Echinacea angustifolia, Salvia officinalis and Melissa officinalis) on cell lines derived from human cervix adenocarcinoma (HeLa cells). The best cytotoxic activity (IC50 = 43.52 ?g/m...

  8. Ethnobotany of Medicinal Plants in Loma and Gena Bosa Districts (Woredas of Dawro Zone, Southern Ethiopia

    Directory of Open Access Journals (Sweden)

    Mathewos Agize

    2013-09-01

    Full Text Available The traditional management, conservation and use of plant diversity with focus on medicinal plants found in and around home gardens in Loma and Gena Bosa Districts of Dawro Zone, Southern Ethiopia was studied. Data was collected between September 2006 and March 2007 to get relevant information and plant specimen of different seasons. The information was gathered through semi-structured interview conducted on 112 traditional healers whose ages ranged between 15 to 121 years. A total of 178 medicinal plants distributed in 64 families were documented in this study. The most frequently used plant part was leaf while the growth form with the highest number (43.82% of representatives among the plants encountered in this study were herbs. About 57.9% medicinal plants were collected from wild while 24.1% were cultivated and 18.5% were both cultivated and collected from wild. A total of 62 human and 27 veterinary diseases were documented in the study. However, only 58% of the traditional healers exercised their indigenous knowledge on treating both human and livestock diseases, while 41.96% practiced treatment of only human diseases. The medicinal plant resources and the associated knowledge of herbal medicine need to be used in a sustainable way and developed for more effective use in the future.

  9. Ethnobotanical study on medicinal plants in the community of Curral Velho, Luís Correia, Piauí, Brazil

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    Jairla Lima Araujo

    2015-05-01

    Full Text Available The use of plants as medication in the state of Piauí, Brazil, has been a common practice passed from generation to generation. This study aimed to analyze the use of medicinal plants by residents of the community Curral Velho, in the municipality of Luís Correia, northern Piauí, Brazil, contributing to register and preserve the traditional botanical knowledge of the community under study and, as a consequence, the state’s. The survey of plant species used as a therapeutic resource was conducted through interviews with a semi-structured questionnaire applied to 38 informants. The plants were collected for scientific identification. Use value (UV, informant consensus factor (ICF, and relative importance (RI of species were determined. We registered 62 species, belonging to 38 families and 57 genera, and the Fabaceae family stood out. Aristolochia triangularis, Petiveria alliaceae, and Stachytarpheta cayennensis had the highest use values (UV = 3.0, and Turnera subulata was the most versatile. Out of the 10 bodily systems identified, those with higher concentration of medicinal species are related to the most ordinary illnesses as general signs (inflammation, fever, respiratory tract diseases, and genitourinary tract diseases. This survey enabled the identification of some relevant aspects concerning the use and knowledge of medicinal plants in the community under study. The diversity of medicinal plants known and the availability of plants in the very community suggest a correlation between use/knowledge of medicinal plants and their availability.

  10. DNA barcoding as a means for identifying medicinal plants of Pakistan

    International Nuclear Information System (INIS)

    DNA barcoding involves the generation of DNA sequencing data from particular genetic regions in an organism and the use of these sequence data to identify or 'barcode' that organism and distinguish it from other species. Here, DNA barcoding is being used to identify several medicinal plants found in Pakistan and distinguished them from other similar species. Several challenges to the successful implementation of plant DNA barcoding are presented and discussed. Despite these challenges, DNA barcoding has the potential to uniquely identify medicinal plants and provide quality control and standardization of the plant material supplied to the pharmaceutical industry. (author)

  11. Studies on saponin production in tropical medicinal plants Maesa argentea and Maesa lanceolata

    Science.gov (United States)

    Faizal, Ahmad; Geelen, Danny

    2015-09-01

    The continuous need for new compounds with important medicinal activities has lead to the identification and characterization of various plant-derived natural products. As a part of this program, we studied the saponin production from two tropical medicinal plants Maesa argentea and M. lanceolata and evaluated several treatments to enhance their saponin production. In this experiment, we present the analyses of saponin production from greenhouse grown plants by means of TLC and HPLC-MS. We observed that the content of saponin from these plants varied depending on organ and physiological age of the plants. In addition, the impact of elicitors on saponin accumulation on in vitro grown plants was analyzed using TLC. The production of saponin was very stable and not affected by treatment with methyl jasmonate, and salicylic acid. In conclusion, Maesa saponins are constitutively produced in plants and the level of these compounds in plants is mainly affected by the developmental or physiological stage.

  12. World-wide every fifth vascular plant species is or was used as medicinal or aromatic plant

    OpenAIRE

    Wittig, Rüdiger (Prof. Dr.); Dingermann, Theo; Sieglstetter, Robert; Xie, Yingzhong; Thiombiano, Adjima; Hahn, Karen

    2015-01-01

    It is common knowledge that plants have been the world-wide most important source of medicines and that they still play this role in developing countries. However, up to now, complete lists of medicinal and aromatic plants (MAP) exist for comparatively few countries. A review of all lists know to the authors reveals the following results: A total of 20.7 % of the plant species analyzed by either publications or own research are or were used as MAP. However, re¬garding single countries, the d...

  13. Medicinal plants used by the Yi ethnic group: a case study in central Yunnan

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    Li Sumei

    2009-04-01

    Full Text Available Abstract Background This paper is based on ethnomedicinal investigation conducted from 1999–2002 in Chuxiong, central Yunnan Province, Southwest China. The Yi medicine has made a great contribution to the ethnomedicinal field in China. Neither case studies nor integrated inventories have previously been conducted to investigate the traditional Yi plants. This paper aims to argue the status and features of medicinal plants used in traditional Yi societies through a case study. Methods The approaches of ethnobotany, anthropology, and participatory rural appraisal were used in the field surveys. Twenty-two informants in four counties were interviewed during eight field trips. Medicinal plant specimens were identified according to taxonomic methods. Results One hundred sixteen medicinal plant species were found to be useful by the local people in the treatment of various diseases or disorders, especially those relating to trauma, gastrointestinal disorders and the common cold. Among these 116 species, 25 species (21.55% were found to have new curative effects and 40 species (34.48% were recorded for their new preparation methods; 55 different species were used in treating wounds and fractures, and 47 were used to treat gastrointestinal disorders. Traditional Yi herbal medicines are characterized by their numerous quantities of herbaceous plants and their common preparation with alcohol. Conclusion Totally 116 species in 58 families of medicinal plants traditionally used by the Yi people were inventoried and documented. The characteristics of medicinal plants were analyzed. Some new findings (such as new curative effects and new preparation methods were recorded These newly gathered ethnobotanical and medicinal data are precious sources for the future development of new drugs, and for further phytochemical, pharmacological and clinical studies.

  14. Inhibitory effects of essential oils of medicinal plants from growth of plant pathogenic fungi.

    Science.gov (United States)

    Panjehkeh, N; Jahani Hossein-Abadi, Z

    2011-01-01

    Plant cells produce a vast amount of secondary metabolites. Production of some compounds is restricted to a single species. Some compounds are nearly always found only in certain specific plant organs and during a specific developmental period of the plant. Some secondary metabolites of plants serve as defensive compounds against invading microorganisms. Nowadays, it is attempted to substitute the biological and natural agents with chemically synthesized fungicides. In the present research, the antifungal activities of essential oils of seven medicinal plants on mycelial growth of three soilborne plant pathogenic fungi were investigated. The plants consisted of Zataria multiflora, Thymus carmanicus, Mentha pieperata, Satureja hortensis, Lavandual officinolis, Cuminum cyminum and Azadirachta indica. The first five plants are from the family Labiatae. Examined fungi, Fusarium oxysporum f.sp. lycopersici, Fusarium solani and Rhizoctonia solani are the causal agents of tomato root rot. Essential oils of Z. multiflora, T. carmanicus, M. pieperata, S. hortensis and C. cyminum were extracted by hydro-distillation method. Essential oils of L. officinalis and A. indica were extracted by vapor-distillation method. A completely randomized design with five replicates was used to examine the inhibitory impact of each concentration (300, 600 and 900 ppm) of each essential oil. Poisoned food assay using potato dextrose agar (PDA) medium was employed. Results showed that essential oils of A. indica, Z. multiflora, T. carmanicus and S. hortensis in 900 ppm at 12 days post-inoculation, when the control fungi completely covered the plates, prevented about 90% from mycelial growth of each of the fungi. While, the essential oils of M. pieperata, C. cyminum and L. officinalis in the same concentration and time prevented 54.86, 52.77 and 48.84%, respectively, from F. solani growth. These substances did not prevent from F. oxysporum f.sp. lycopersici and R. solani growth. Minimum inhibitory concentration (MIC) of essential oils of T. carmanicus, Z. multiflora and A. indica from R. solani and F. solani growth was 900 and 600 ppm, respectively. In addition, the MIC of essential oils of these plants and essential oil of S. hortensis from F. oxysporum f.sp. lycopersici growth was 900 ppm. The MIC of essential oils of M. pieperata, C. cyminum and L. officinalis from F. solani growth was 900 ppm. PMID:22702190

  15. World Trade in Medicinal Plants from Spanish America, 1717–1815

    Science.gov (United States)

    Gänger, Stefanie

    2015-01-01

    This article outlines the history of the commerce in medicinal plants and plant-based remedies from the Spanish American territories in the eighteenth century. It maps the routes used to transport the plants from Spanish America to Europe and, along the arteries of European commerce, colonialism and proselytism, into societies across the Americas, Asia and Africa. Inquiring into the causes of the global ‘spread’ of American remedies, it argues that medicinal plants like ipecacuanha, guaiacum, sarsaparilla, jalap root and cinchona moved with relative ease into Parisian medicine chests, Moroccan court pharmacies and Manila dispensaries alike, because of their ‘exotic’ charisma, the force of centuries-old medical habits, and the increasingly measurable effectiveness of many of these plants by the late eighteenth century. Ultimately and primarily, however, it was because the disease environments of these widely separated places, their medical systems and materia medica had long become entangled by the eighteenth century. PMID:25498437

  16. World trade in medicinal plants from Spanish America, 1717-1815.

    Science.gov (United States)

    Gänger, Stefanie

    2015-01-01

    This article outlines the history of the commerce in medicinal plants and plant-based remedies from the Spanish American territories in the eighteenth century. It maps the routes used to transport the plants from Spanish America to Europe and, along the arteries of European commerce, colonialism and proselytism, into societies across the Americas, Asia and Africa. Inquiring into the causes of the global 'spread' of American remedies, it argues that medicinal plants like ipecacuanha, guaiacum, sarsaparilla, jalap root and cinchona moved with relative ease into Parisian medicine chests, Moroccan court pharmacies and Manila dispensaries alike, because of their 'exotic' charisma, the force of centuries-old medical habits, and the increasingly measurable effectiveness of many of these plants by the late eighteenth century. Ultimately and primarily, however, it was because the disease environments of these widely separated places, their medical systems and materia medica had long become entangled by the eighteenth century. PMID:25498437

  17. Heavy Metal Analysis of Some Anti-Diabetic Medicinal Plants in Côte d'Ivoire

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    A.A.D. Djama

    2012-09-01

    Full Text Available Trace elements concentrations in four plants with anti-diabectic potency in Côte d’Ivoire were studied using Energy-Dispersive X-Ray Fluorescence (EDXRF Analysis technique. The aim of this study is to determine qualitatively and quantitatively trace elements in these plants and their medicinal roles in the human body. Leaves and roots were analyzed for their trace element contents. The plant samples were found to contain essential trace elements such as Cr, V, Zn and Mn which are well known for their important roles in anti-diabectic preparations (herbal drugs. All the medicinal plants were found to be rich more than one of the essential elements under study. The elemental concentrations in different part (root, stem and leaf of the medicinal plants and their biological effects are discussed.

  18. Survey on medicinal plants and spices used in Beni-Sueif, Upper Egypt

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    Mohamed Abdelhalim A

    2011-06-01

    Full Text Available Abstract Background This study was conducted to identify medicinal plants and spices used for medicine by the community of Beni-Sueif, Upper Egypt. Methods Ethnobotanical data from local people was collected using direct interviews and a semi-structured questionnaire. Results Forty-eight plant species belonging to twenty-seven families and forty-seven genera were encountered during the study. Their botanical and vernacular names, plant parts used and medicinal uses are given. Results of the study were analyzed using two quantitative tools. The factor informant consensus indicated the agreement in the use of plants and the fidelity level indicated the ratio between the number of informants who independently suggested the use of a species for the same major purpose and the total number of informants who mentioned the plant for any use. The results of the factor informant consensus showed that the cardiovascular category has the greatest agreement, followed by the immunological, gastrointestinal and respiratory categories. The most important species according to their fidelity are: Hibiscus sabdariffa L. for the cardiovascular category; Trigonella foenum-graecum L. for the immunological category; Mentha piperita L. for the gastrointestinal category and Pimpinella anisum L. for the respiratory category. Conclusions Medicinal plants are still used for treatment in Beni-Sueif community despite the availability of prescribed medications. Documentation of this ethnomedicinal knowledge is important. Evaluation of pharmacological activity for the promising medicinal plants is suggested.

  19. Ethnopharmacological Survey of Medicinal Plants in Malaysia, the Kangkar Pulai Region

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    T. Aburjai

    2012-01-01

    Full Text Available The medicinal plants play an important role in rural health care system throughout the world in remedying and preventing various kinds of diseases. This study documented the use of plants as traditional herbal medicine in the Kangkar Pulai region Johor, Malaysia. It also identified the homogeneity of informant knowledge on medicinal plants suitable for different ailments and types of plants most favored for the treatment of each ailment in the study. The information was gathered through semi-structured interviews, discussions with key informants and informal conversations with local people and herbal practitioners. The data was calculated based on informant consensus factor (Fic and use value (UV. Information on 40 medicinal plants species from 29 taxonomic plant families used for traditional treatment of different diseases/ailments was documented. The informant consensus factor values (Fic showed that the local people tend to agree more with each other in terms of the plants used to treat sexual weakness (0.95, blood pressure (0.94, diabetes (0.93, delivery and female problems (0.90, hair problems and dandruff (0.87, respiratory disorder (0.86 and kidney problems (0.85. By contrast, digestive problems (0.76 and skin problems (0.71 and inflammation pain (0.70 were found to have low Fic values. Calculated values of the UV and Fic indicate that this community is knowledgeable on healing and treatment using traditional herbal medicines.

  20. TAHLAB (SPIRULINA) AND FEW OTHER MEDICINAL PLANTS HAVING ANTI-OXIDANT & IMMUNOMODULATORY PROPERTIES DESCRIBED IN UNANI MEDICINE - A REVIEW

    OpenAIRE

    Md. Anzar Alam*, Nafis Haider , Shamim Ahmed , Md. Tanwir Alam and Abdul Azeez

    2013-01-01

    : Antioxidants are substances that may protect cells from the damage caused by unstable molecules known as free radicals; free radicals damage may lead to cancer and other diseases. Some of the example of antioxidants are like β-carotene, lycopene, Vit. C, E & A and other substances which are found in variety of fruits, vegetables, algae (spirulina) & other medicinal plants. Spirulina (Blue green algae) is a microscopic single cell alga which grows in fresh water and has a simple structure bu...

  1. Cultivation, Phytochemical Studies, Biological Activities and Medicinal Uses of Aloe ferox, Grandfather of Aloes an Important Amazing Medicinal Plant

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    Chandra Sekhar Singh Bhaludra

    2013-01-01

    Full Text Available Aloe ferox is an ethnomedicinal and economic plant in India and worldwide. It is a common ingredient in Ayurvedic medicine. To date, many scientific studies have been carried out but a comprehensive review on this plant is lacking. This review aims to cover the cultivation practices and biological activities, the active compounds derived from Aloe ferox. Literature survey revealed that the pharmacological effects of Aloe ferox range from anti-oxidant, anti-inflammatory, anti-microbial, anti-diabetic, cardiovascular diseases, neurodegeneration to anti-cancer property. Over 130 biological active compounds consisting of fatty acid, sterols, sesquiterpene lactones, flavonoids and carbohydrates have been identified from different parts of the plant. Aloe ferox is similar to Aloe vera but it has 20 times more nutritional activities. Many of these active compounds were derived from the leaf gel and have been evaluated for a number of biological activities. Despite the encouraging results demonstrated by these studies and the traditional use as nutraceutical agent, analgesic, anti-inflammatory, wound healing, immune modulator, anti-tumor, anti-bacterial, antifungal, antiviral and toxicity of Aloe ferox leaf extracts or its derivatives are absent. Thus, a systematic documenting review would provide more insights and spur further research that would lead to production of safer and economical alternative medicine from Aloe ferox. In this review we briefly introduced its phytochemical, biological activities, medicinal uses and cultivation practices which can be useful as a potential drug in pharmaceutical industry. The propagation of medicinal plant Aloe ferox is vital for sustainable uses in modern world.

  2. Comparative analysis of medicinal plants used in traditional medicine in Italy and Tunisia

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    Ghedira Kamel

    2009-10-01

    Full Text Available Abstract Background Italy and Tunisia (Africa for the Romans, facing each other on the opposite sides of the Mediterranean Sea, have been historically linked since the ancient times. Over the centuries both countries were mutually dominated so the vestiges and traces of a mutual influence are still present. The aim of the present study is to conduct a comparative analysis of the medicinal species present in the respective Floras in order to explore potential analogies and differences in popular phytotherapy that have come out from those reciprocal exchanges having taken place over the centuries Methods The comparative analysis based on the respective floras of both countries takes into consideration the bulk of medicinal species mutually present in Italy and Tunisia, but it focuses on the species growing in areas which are similar in climate. The medicinal uses of these species are considered in accordance with the ethnobotanical literature. Results A list of 153 medicinal species belonging to 60 families, present in both floras and used in traditional medicine, was drawn. A considerable convergence in therapeutic uses of many species emerged from these data. Conclusion This comparative analysis strengthens the firm belief that ethno-botanical findings represent not only an important shared heritage, developed over the centuries, but also a considerable mass of data that should be exploited in order to provide new and useful knowledge.

  3. Medicinal plants and ethnomedicine in peril: a case study from Nepal himalaya.

    Science.gov (United States)

    Kunwar, Ripu M; Lamichhane Pandey, Mina; Mahat Kunwar, Laxmi; Bhandari, Ananta

    2014-01-01

    The impacts of climate change were severe on indigenous medicinal plant species and their dependent communities. The harvesting calendar and picking sites of these species were no longer coinciding and the changes were affecting harvesters' and cultivators' abilities to collect and use those species. Secondary sites: road-heads, wastelands, regenerated forests, and so forth, were being prioritized for collection and the nonindigenous medicinal plant species were being increasingly introduced into the medical repertoire as a substitution and to diversify the local medicinal stock. Acceptance and application of nonindigenous species and sites for livelihood and ethnopharmacopoeias with caution were considered as an important adaptation strategy. Findings on species and site specific accounts urged further researches on medicinal plants, ethnomedicine, and their interrelationship with impacts of climate change. PMID:24734114

  4. Trace element profile of some selected medicinal plants of Manipur, India

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    C.h.B. Devi

    2013-10-01

    Full Text Available Herbal remedies areconsidered the oldest forms of health care known to mankind on this earth. Thedifferent elemental concentration at trace level of medicinal plant also playsan important role in the treatment of diseases. Different parts of the plantssuch as roots, leaves, stem, bark, fruits, seeds etc depending on the plantspecies are generally used for the preparation of traditional medicines. Inthis present work, some selected medicinal plants were collected from differentparts of Manipur, India and analysed by using EDXRF (Energydispersive X-ray fluorescence, a fast multi-elemental analytical technique.Fourteen elements namely, Potassium, Calcium, Titanium, Vanadium, Chromium,Manganese, Iron, Copper, Zinc, Arsenic, Selenium, Bromine, Rubidium andStrontium were detected. Also the elemental content of each plant part has beencorrelated with its potential application as herbal medicine.

  5. Physico-chemical and antioxidant properties of two medicinal wild plants grown in Moldova region

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    Sorina Ropciuc

    2015-05-01

    Full Text Available The major objective of this study is to report physico-chemical (moisture, ash, protein, total phenolic compounds and ascorbic acid and the antioxidant properties of methanol extracts of nettle (Urtica dioica L. and typical romaine spice "leurda" (Allium ursinum, wild garlic fresh and dried. The antioxidant properties of methanol extract of medicinal herbs were evaluated using free radical scavenging test. The phenols were extracted from the medicinal plants with methanol solvent and were quantified by the Folin-Ciocalteu method. The ascorbic acid content varied between 77.94 mg/100g in the fresh Urtica dioica L. and 39.55 from fresh Allium ursinum. The results showed that the total phenolic compounds in all medicinal plants decreased along processing. These results suggest that the medicinal plants sample extract with highest polyphenolic content will indicates the possibility of using them  as ingredients in functional foods.

  6. Medicinal plant knowledge of the Bench ethnic group of Ethiopia: an ethnobotanical investigation

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    Woldu Zerihun

    2009-11-01

    Full Text Available Abstract Background Plants have traditionally been used as a source of medicine in Ethiopia since early times for the control of various ailments afflicting humans and their domestic animals. However, little work has been made in the past to properly document and promote the knowledge. Today medicinal plants and the associated knowledge in the country are threatened due to deforestation, environmental degradation and acculturation. Urgent ethnobotanical studies and subsequent conservation measures are, therefore, required to salvage these resources from further loss. The purpose of the present study was to record and analyse traditional medicinal plant knowledge of the Bench ethnic group in Southwest Ethiopia. Methods Semi-structured interviews were conducted with Bench informants selected during transect walks made to houses as well as those identified as knowledgeable by local administrators and elders to gather data regarding local names of medicinal plants used, parts harvested, ailments treated, remedy preparation methods, administration routes, dosage and side effects. The same method was also employed to gather information on marketability, habitat and abundance of the reported medicinal plants. Purposive sampling method was used in the selection of study sites within the study district. Fidelity Level (FL value was calculated for each claimed medicinal plant to estimate its healing potential. Results The study revealed 35 Bench medicinal plants: 32 used against human ailments and three to treat both human and livestock ailments. The majority of Bench medicinal plants were herbs and leaf was the most frequently used part in the preparation of remedies. Significantly higher average number of medicinal plants was claimed by men, older people and illiterate ones as compared to women, younger people and literate ones, respectively. The majority of the medicinal plants used in the study area were uncultivated ones. Conclusion The study revealed acculturation as the major threat to the continuation of the traditional medical practice in the study area. Awareness should, therefore, be created among the Bench community, especially the young ones, by concerned organizations and individuals regarding the usefulness of the practice.

  7. A comparative study on medicinal plants used in Akha's traditional medicine in China and Thailand, cultural coherence or ecological divergence?

    DEFF Research Database (Denmark)

    Inta, A.; Shengji, P.; Balslev, Henrik; Wangpakapattanawong, P.; Trisonthi, C.

    2008-01-01

    Aim of the study : The survey aims to study the effect of geographic separation of ethnic groups on local knowledge of medicinal plants used by Akha people in Thailand and China, who were separated 100-120 years ago, to see how different the two geographically distinct but culturally similar groups were in this respect. Materials and methods : Interviewing 10 villagers in each of five Akha villages, three in Thailand and two in China, about which plants they used and how they used them. Results ...

  8. The Assessment of Pesticides Residues in Some Organic Cultivated and Wild-Collected Medicinal Plants in Albania

    OpenAIRE

    FERDI BRAHUSHI; ENDRIT KULLAJ

    2014-01-01

    Pesticide residues in environment are found in soil, water and plants due to the extensive use of pesticides for agricultural purposes. The residues of pesticides in medicinal plants are of high concern as they are toxic for human life since these plants are used for medicinal purposes. The objective of current study was to estimate the presence of pesticide residues in some organic cultivated and wild-collected medicinal plants in Albania during the years 2010–2013. The determination of pest...

  9. Endophytic and rhizospheric bacterial communities isolated from the medicinal plants Echinacea purpurea and Echinacea angustifolia.

    Science.gov (United States)

    Chiellini, Carolina; Maida, Isabel; Emiliani, Giovanni; Mengoni, Alessio; Mocali, Stefano; Fabiani, Arturo; Biffi, Sauro; Maggini, Valentina; Gori, Luigi; Vannacci, Alfredo; Gallo, Eugenia; Firenzuoli, Fabio; Fani, Renato

    2014-09-01

    In this work we analyzed the composition and structure of cultivable bacterial communities isolated from the stem/leaf and root compartments of two medicinal plants, Echinacea purpurea (L.) Moench and Echinacea angustifolia (DC.) Hell, grown in the same soil, as well as the bacterial community from their rhizospheric soils. Molecular PCR-based techniques were applied to cultivable bacteria isolated from the three compartments of the two plants. The results showed that the two plants and their respective compartments were characterized by different communities, indicating a low degree of strain sharing and a strong selective pressure within plant tissues. Pseudomonas was the most highly represented genus, together with Actinobacteria and Bacillus spp. The presence of distinct bacterial communities in different plant species and among compartments of the same plant species could account for the differences in the medicinal properties of the two plants. [Int Microbiol 2014; 17(3):165-174]. PMID:26419456

  10. Indigenous plants and schistosomiasis control in south africa:molluscicidal activity of some zulu medicinal plants

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    John A. O. Ojewole

    2004-01-01

    Full Text Available This work reviews plant molluscicides and presents preliminary findings of a molluscicidal screening programme carried out on some South African candidate molluscicidal plants. The overall objective of studies on plant molluscicides is to complement methods for controlling snails acting as intermediate hosts of schistosomes. In the last two decades, plant molluscicides have received considerable attention in the search for cheaper, effective, environmentally-friendly alternatives to expensive, imported chemotherapeutic agents and synthetic molluscicides used in schistosomiasis control. Although molluscicidal screening programmes have been conducted in many African countries, only relatively little efforts have been made to identify South African plants which could be suitable for use locally as plant molluascicides. The attraction of a locally grown molluscicidal plant is based on the development of a philosophy of selfreliance and community participation. This approach is dependent on community recognition of the infection as a public health menace, and their acceptance of the proposed control measures. Schistosomiasis has been recognized as a primary health problem in KwaZulu-Natal Province of South Africa, especially among the people in the rural communities that depend on river-water for all their water requirements. Concerns for schistosomiasis in the Province have indeed been matched by a 75% prevalence of Schistosoma haematobium infection among children aged 6 to 16 years. Forty-one medicinal plants commonly used by traditional healers for the treatment of schistosomiasis in KwaZulu-Natal Province of South Africa were evaluated for molluscicidal activity according to WHO?s method, using niclosamide (BayluscideÒ as reference molluscicide for comparison. Adult Bulinus africanus and Biomphalaria pfeifferi were exposed to sublethal and lethal doses of crude, aqueous extracts of the Zulu antischistosomal plants for a period of 24 hours. Results obtained indicate that 14 (34% of the 41 plants examined possess moderate to strong molluscicidal properties. Sublethal, toxic effects of the active plant extracts on the snails included retraction of the foot-sole and mobility, swelling of the cephalopedal mass, and haemorrhagic blistering in the subepithelium of the foot-sole, while administration of lethal doses resulted in cessation of mobility, severe swelling of the cephalopedal mass, increased mucous secretion, and haemorrhage. It is speculated that part of the molluscicidal actions of the active plant extracts could involve distruption of the snails? foot-sole epithelium osmoregulatory physiology and enzyme-mediated pathways. However, osmolality and electrolyte studies, as well as enzymatic, histochemical and biochemical studies are required to substantiate these possible modes of molluscicidal action of the South African candidate plant molluscicides. Treatment of schistosomiasis is based on chemotherapy with praziquantel, which is the currently-available drug of choice for all forms of the disease. However, since resistance to praziquantel has been demonstrated in many schistosomiasis endemic areas of the world; of necessity is a holistic approach which should include not only reducing the disease burden in schistosomiasis-infected persons, but also measures interfering with the life-cycle of the parasite by eliminating the intermediate host snail vectors. Inexpensive, non-toxic, effective and readily-available alternative drugs from natural sources are certainly warranted

  11. Traditional knowledge and modern trends for Asian medicinal plants in Bulgaria from an ethnobotanical view

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    Anely Nedelcheva

    2012-07-01

    Full Text Available Background: Asian medicinal plants are an integral part of the Bulgarian traditions and folk botanical knowledge and as from the past until now, have their place in the Bulgarian market. In the last decade the interest in new plant-based products has increased. Materials and Methods: This study was conducted with the aim to bring out the facts about the diversity of Asian medicinal plants, present in medicinal plant-based products that are recently available on the Bulgarian market. The survey data was gathered during a period of 7 years (2003-2010 from the main national databases that contain information about herbal medicines and interviews, along with field-collected data. Results: More than 185 species of medicinal plants, belonging to 38 families and 137 genera were registered. Only twenty species were found to be used mostly in plant-based products for example Panax ginseng, Eleuterococcus senticosus, Ginkgo bilоba, Camellia sinensis, Zingiber officinale, Rhodiola rosea, Euphorbia pallasii, Scutelaria baicalensis, Garcinia cambogia, Hibiscus spp., Cinnamomum verum, Piper nigrum, Curcuma zedoaria, Syzigium aromaticum, etc. Most of them can be compounds of plant extract products, herbal remedies, spices, food and food additives, which are mainly proved to be beneficial as immune stimulants, memory enhancers, antitumor agents, sedatives, aphrodisiacs, antimycotics, wellness tea, body weight reducers, stimulants, blood pressure reducers, etc. Conclusions: Some of the species were used in the past for different purposes, while others are completely unknown and exotic. The occurrence of new combinations and mixtures containing both traditional Bulgarian and Asian folk medicine herbs was observed. This particular way of development, of traditional medicine in modern life, is of special interest to the ethnobotanists and is discussed further in the study.

  12. Investigation of the effects of selected medicinal plants on experimental thrombosis.

    Science.gov (United States)

    Olajide, O A

    1999-05-01

    Six medicinal plants indigenous to Africa were evaluated for their activity on experimental thrombosis in mice. Of the plants screened, the extract of Commiphora molmol exhibited the strongest antithrombotic activity, while the extract of Ageratum conyzoides showed no marked activity. This study established the antithrombotic effect of the extracts of Azadiractha indica, Bridelia ferruginea, Commiphora molmol, Garcinia kola and Curcuma longa. PMID:10353165

  13. Preliminary assessment of medicinal plants used as antimalarials in the southeastern Venezuelan Amazon

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    Caraballo Alejandro

    2004-01-01

    Full Text Available Eighteen species of medicinal plants used in the treatment of malaria in Bolívar State, Venezuela were recorded and they belonged to Compositae, Meliaceae, Anacardiaceae, Bixaceae, Boraginaceae, Caricaceae, Cucurbitaceae, Euphorbiaceae, Leguminosae, Myrtaceae, Phytolaccaceae, Plantaginaceae, Scrophulariaceae, Solanaceae and Verbenaceae families. Antimalarial plant activities have been linked to a range of compounds including anthroquinones, berberine, flavonoids, limonoids, naphthquinones, sesquiterpenes, quassinoids, indol and quinoline alkaloids.

  14. Bioactivity of indigenous medicinal plants against the cotton whitefly, Bemisia tabaci.

    Science.gov (United States)

    Hammad, E Abou-Fakhr; Zeaiter, A; Saliba, N; Talhouk, S

    2014-01-01

    Forty-one methanol extracts of 28 indigenous medicinal plant species were tested for their insecticidal bioactivity against cotton whitefly, Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae), adults and second nymphal instars under controlled conditions. This study is within a bioprospection context, in the form of utilizing local plant species as an alternative in sustainable agriculture development. Eighteen and nine plant extracts caused a significant decrease in number of live adult and nymphal whiteflies, respectively, compared to the control. This is the first report for the potential effect on survival of insects for 22 out of 28 tested medicinal plant species. Whole plant extracts of Ranunculus myosuroudes Boiss. and Kotschy (Ranunculaceae),Achillea damascena L. (Asteraceae), and Anthemis hebronica Boiss. and Kotschy (Asteraceae) and leaf extracts of Verbascum leptostychum DC. (Scrophulariaceae) and Heliotropium rotundifolium Boiss. (Borangiaceae) caused both repellent and toxic effects against the adult and second nymphal instars, respectively. Extracts of leaves and stems of Anthemis scariosa Boiss. (Asteraceae) and Calendula palestina Pers. (Asteraceae) were found to be more bioactive against the adult and nymphal instars, respectively, than extracts of other plant parts, such as flowers. Thus, the bioactive extracts of these medicinal plants have the potential to lower whitefly populations in a comprehensive pest management program in local communities, pending cultivation of these medicinal plant species. PMID:25373231

  15. An Evidence-based Review on Medicinal Plants used for the Treatment of Peptic Ulcer in Traditional Iranian Medicine

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    Zahra Abbasabadi

    2013-01-01

    Full Text Available Many medicinal plants have been identified in Traditional Iranian Medicine (TIM for the treatment of Peptic Ulcer (PU but they are still unknown to scientific community. In the present study anti PU activity of these remedies were systematically reviewed and identified. For this purpose, medicinal plants proposed for the management of PU in TIM were collected from TIM sources and they were searched in modern medical databases like PubMed, Scirus, Sciencedirect and Google Scholar to find studies confirmed their efficacy. Findings from modern investigations support the claims of TIM about the efficacy of many of these plants in PU. For example, the oleogum resin of Boswellia carterii and B. serrata as a beneficial remedy for PU in TIM were demonstrated to have wound healing, cytoprotective, antisecretory, antacid, prostaglandin production and inflammatory modulating properties. Fruit and leaves of Myrtus communis was found to be antioxidant, anti H. pylori, wound healing, antisecretory, antacid and cytoprotective. The aerial part from Melissa officinalis exerts its beneficial effects in PU by antioxidant, anti H. pylori, prostaglandin elevating, cytoprotective, antisecretory, antacid and leukotriene reducing properties. Furthermore, Polygonum species demonstrated its function on PU with prostaglandin enhancement, inflammatory modulation, wound healing, cytoprotection, antacid, antioxidant and anti-H. pylori activity. In contrast, for some of herbal remedies used in TIM such as Dolichos lablab flower, Symphytum species, Zizyphus spina-christi fruit, Alisma plantago-aquatica, Cupressus sempervirens fruit, Acacia Arabica gum, Cyperus species root, Althaea officinalis flower and Nymphaea alba flower there is no enough evidence in modern medicine to prove their effectiveness in the management of PU. Pharmacological and clinical studies for evaluation of efficacy of these herbs in PU and their possible mechanisms of action are recommended.

  16. Cytotoxic Effects of (5 Medicinal Plants on Mitosis in Allium cepa Root Tips

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    I.J. Udo

    2014-03-01

    Full Text Available The study was conducted to investigate the effects that plant extracts from 5 medicinal plants may have on mitosis in Allium cepa. Root of A .cepa were immersed in alcoholic extracts at the concentrations of 0, 25, 50, 75 and 100 mg/mL, respectively for each of the following plants: Gnetum africanum Welw., Lasianther aafricana P. Beauv, Ocimum gratissimum Linn., Telfairia occidentalis Hook F. and Vernonia amygdalina Del. Leafy vegetable which are commonly used in herbal medicine. Results obtained show that the various concentrations of the extracts from test plants had toxic effects on the cells, which caused significant reduction (p<0.05 in the mitotic index when compared with the control. Other effects were prophase inhibition, the delay of mitosis and nuclear lesion. The cytotoxic effect makes a case for a precaution in the use of the leafy extracts in herbal medicine practice.

  17. Estimation of trace elements in some anti-diabetic medicinal plants using PIXE technique

    International Nuclear Information System (INIS)

    Trace elemental analysis was carried out in various parts of some anti-diabetic medicinal plants using PIXE technique. A 3 MeV proton beam was used to excite the samples. The elements Cl, K, Ca, Ti, Cr, Mn, Fe, Ni, Cu, Zn, Br, Rb and Sr were identified and their concentrations were estimated. The results of the present study provide justification for the usage of these medicinal plants in the treatment of diabetes mellitus (DM) since they are found to contain appreciable amounts of the elements K, Ca, Cr, Mn, Cu, and Zn, which are responsible for potentiating insulin action. Our results show that the analyzed medicinal plants can be considered as potential sources for providing a reasonable amount of the required elements other than diet to the patients of DM. Moreover, these results can be used to set new standards for prescribing the dosage of the herbal drugs prepared from these plant materials

  18. Vibriocidal activity of certain medicinal plants used in Indian folklore medicine by tribals of Mahakoshal region of central India

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    Sharma Anjana

    2009-01-01

    Full Text Available Objectives: Screening of the medicinal plants and determination of minimum inhibitory concentration (MIC against Vibrio cholerae and Vibrio parahaemolyticus. Materials and Methods: A simple in vitro screening assay was employed for the standard strain of Vibrio cholerae, 12 isolates of Vibrio cholerae non-O1, and Vibrio parahaemolyticus. Aqueous and organic solvent extracts of different parts of the plants were investigated by using the disk diffusion method. Extracts from 16 medicinal plants were selected on account of the reported traditional uses for the treatment of cholera and gastrointestinal diseases, and they were assayed for vibriocidal activities. Results: The different extracts differed significantly in their vibriocidal properties with respect to different solvents. The MIC values of the plant extracts against test bacteria were found to be in the range of 2.5-20 mg/ml. Conclusions: The results indicated that Lawsonia inermis, Saraca indica, Syzygium cumini, Terminalia belerica, Allium sativum, and Datura stramonium served as broad-spectrum vibriocidal agents.

  19. Alpha-Glucosidase Enzyme Biosensor for the Electrochemical Measurement of Antidiabetic Potential of Medicinal Plants

    Science.gov (United States)

    Mohiuddin, M.; Arbain, D.; Islam, A. K. M. Shafiqul; Ahmad, M. S.; Ahmad, M. N.

    2016-02-01

    A biosensor for measuring the antidiabetic potential of medicinal plants was developed by covalent immobilization of α-glucosidase (AG) enzyme onto amine-functionalized multi-walled carbon nanotubes (MWCNTs-NH2). The immobilized enzyme was entrapped in freeze-thawed polyvinyl alcohol (PVA) together with p-nitrophenyl-α- d-glucopyranoside (PNPG) on the screen-printed carbon electrode at low pH to prevent the premature reaction between PNPG and AG enzyme. The enzymatic reaction within the biosensor is inhibited by bioactive compounds in the medicinal plant extracts. The capability of medicinal plants to inhibit the AG enzyme on the electrode correlates to the potential of the medicinal plants to inhibit the production of glucose from the carbohydrate in the human body. Thus, the inhibition indicates the antidiabetic potential of the medicinal plants. The performance of the biosensor was evaluated to measure the antidiabetic potential of three medicinal plants such as Tebengau ( Ehretis laevis), Cemumar ( Micromelum pubescens), and Kedondong ( Spondias dulcis) and acarbose (commercial antidiabetic drug) via cyclic voltammetry, amperometry, and spectrophotometry. The cyclic voltammetry (CV) response for the inhibition of the AG enzyme activity by Tebengau plant extracts showed a linear relation in the range from 0.423-8.29 μA, and the inhibition detection limit was 0.253 μA. The biosensor exhibited good sensitivity (0.422 μA/mg Tebengau plant extracts) and rapid response (22 s). The biosensor retains approximately 82.16 % of its initial activity even after 30 days of storage at 4 °C.

  20. An ethnobotanical survey of medicinal plants used in Terai forest of western Nepal

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    Singh Anant

    2012-05-01

    Full Text Available Abstract Background Nepal Himalayas have been known as a rich source for valuable medicinal plants since Vedic periods. Present work is the documentation of indigenous knowledge on plant utilization as natural remedy by the inhabitants of terai forest in Western Nepal. Methods Study was conducted during 2010–2011 following standard ethnobotanical methods. Data about medicinal uses of plants were collected by questionnaire, personal interview and group discussion with pre identified informants. Voucher specimens were collected with the help of informants, processed into herbarium following standard methods, identified with the help of pertinent floras and taxonomic experts, and submitted in Department of Botany, Butwal Multiple Campus, Tribhuvan University, Nepal for future references. Results During the present study 66 medicinal plant species belonging to 37 families and 60 genera has been documented. These plants were used to treat various diseases and ailments grouped under 11 disease categories, with the highest number of species (41 being used for gastro-intestinal disorders, followed by dermatological disorders (34. In the study area the informants’ consensus about usages of medicinal plants ranges from 0.93 to 0.97 with an average value of 0.94. Herbs (53% were the primary source of medicine, followed by trees (23%. Curcuma longa (84% and Azadirachta indica (76% are the most frequently and popularly used medicinal plant species in the study area. Acacia catechu, Bacopa monnieri, Bombax ceiba, Drymaria diandra, Rauvolfia serpentina, and Tribulus terrestris are threatened species which needs to be conserved for future use. Conclusions The high degree of consensus among the informants suggests that current use and knowledge are still strong, and thus the preservation of today's knowledge shows good foresight in acting before much has been lost. The connections between plant use and conservation are also important ones, especially as the authors note that neither the local inhabitants nor the government is addressing the potential loss of valuable species in this region.

  1. Gamma Radiation Impact on the Survival Microflora and Biochemical Constituents of Stored Anise Seeds (Pimpenella anisum L.)

    International Nuclear Information System (INIS)

    Anise seeds (Pimpenella anisum L.) were exposed to gamma irradiation doses (0, 4, 8, 16 and 32 KGy). Irradiated and un-irradiated anise seeds were stored for 3, 6 and 12 months and tested for their microbial population . In addition, the chemical constituents (volatile oils, fatty acids, lipids and sugars) were evaluated. The predominant microorganisms contaminated anise seeds include different fungal species identified as Aspergillus niger, A. ochraceus, A. parasiticus, A. flavus, A. fumigatus , Penicillium funiculosum , P. italicum , Rhizopus sp. and Trichoderma viride. Different bacterial species as Bacillus circulans, B. subtilis, B. megaterium, B. brevis, Pseudomonas fluorescens, P. oleourans and Alicyclobacillus acidocaldarius were recorded. The imposed irradiation doses showed a promising effect to decontaminate the microbial load , which in turn showed prolong the storage periods. Volatile oil content was relatively declined during storage. In addition, some alternations were happened regarding the essential oils constituents. However, the applied irradiation doses maintained the volatile oil content and retained its constituents near to the normal control. Total lipids content were not influenced by either the applied storage periods or the used gamma irradiation doses. However, the fatty acids methyl ester showed some changes due to the imposed treatments. Sugars content were increased in the stored and un-irradiated seeds, however, the exposure to gamma radiation reduced this increase and retained sugars content near to the normal level of the control seeds.

  2. Sacred groves of north Malabar: treasure trove of endemic and rare medicinal plants

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    K. Subrahmanya Prasad

    2011-01-01

    Full Text Available (Abstract selected from presentation in National Conference on Biodiversity of Medicinal and Aromatic Plants: Collection, Characterization and Utilization, held at Anand, India during November 24-25, 2010  Sacred groves are one of the finest examples of traditional in situ conservation practices and act as treasure house of endemic, endangered and rare plants. Endemic species of any geographical region, throw light on the biogeography of the area, areas of extinction and evolution of the flora. Twelve famous sacred groves of north Malabar region of Kerala were selected for study. Studies were aimed at the documentation of floristic diversity with special reference to endemic as well as RET medicinal plants and to know threats to them. Present inventory accounted for a total of 99 endemic angiosperms, of which 28 qualified for RET categories. Their role in germplasm conservation is evident from the fact that not a single plant is common to the groves studied and restriction of 47 endemic plants to any one of the grove. There are 59 endemic plants, of which 18 belong to RET category are in high demand due to their medicinal properties. Medicinal plant diversity varies from a minimum of 65% to a maximum of 91% while that of endemic plants ranges from 11% in Andallur to 18% in Edayilakkad. Present study revealed the endemic plant diversity of these groves and also their role in the conserving germplasms of wild yam, figs, pepper, mango and a variety of endemic medicinal plants. Like other groves of Kerala, these are also facing the threat of extinction from increasing anthropogenic activities and there is an urgent need of complete protection and public awareness for the existence of these near-climax communities.

  3. Patented antiinflammatory plant drug development from traditional medicine.

    Science.gov (United States)

    Darshan, S; Doreswamy, R

    2004-05-01

    Patents secured on antiinflammatory plant drugs derived from 38 plants are reviewed. An attempt has been made to compare the modern and traditional use of plant drugs and to establish the relevance of folk claims in developing modern drugs. The role of plant botanicals such as polysaccharides, terpenes, curcuminoids, alkaloids, etc. in alleviating inflammatory diseases including arthritis, rheumatism, acne skin allergy and ulcers is highlighted. Chemicals that alleviate swelling are derived from plants including grape, boswellia, turmeric, devil's claw and some essential oils such as clove, eucalyptus, rosemary, lavender, mint, myrrh, millefolia and pine have been patented and used as mixed formulations. Plants containing polysaccharides are the most potent in curing inflammatory diseases. PMID:15173991

  4. Phytochemical and Biological Activities of Four Wild Medicinal Plants

    OpenAIRE

    Anwar Ali Shad; Shabir Ahmad; Riaz Ullah; AbdEl-Salam, Naser M.; Fouad, H; Najeeb Ur Rehman; Hidayat Hussain; Wajid Saeed

    2014-01-01

    The fruits of four wild plants, namely, Capparis decidua, Ficus carica, Syzygium cumini, and Ziziphus jujuba, are separately used as traditional dietary and remedial agents in remote areas of Khyber Pakhtunkhwa, Pakistan. The results of our study on these four plants revealed that the examined fruits were a valuable source of nutraceuticals and exhibited good level of antimicrobial activity. The fruits of these four investigated plants are promising source of polyphenols, flavonoids, alkaloid...

  5. Folk medicinal plants of Nushki, district Chagai, Pakistan

    International Nuclear Information System (INIS)

    Ethno botanical survey conducted in Nushki, District Chagai revealed that the local people use 50 species of plants in traditional heath care system. The most important health problems cured by the traditional use of plants include stomach related disorders, malarial, typhoid and common fevers, liver and kidney disorders, cough and related ailments, aphrodisiac, gonorrhea, diuretic, diabetes, eye diseases, skin allegories, rashes, diarrhea and dysentery etc. Elders, especially women, appeared to be more knowledgeable. Most plants had multiple uses. (author)

  6. Traditional Medicinal Plants Used by People in Libo-Kemkem District, South Gondar, Ethiopia

    Directory of Open Access Journals (Sweden)

    Yalew Addisie

    2012-05-01

    Full Text Available The present study was conducted between June 2010 and September 2010, to document medicinal plant species traditionally used by peoples in Libo-kemekem district, South Gondar, Ethiopia. Ethnobotanical data were collected using semi structured interviews, focused group discussion and field observations. A total of 52 medically important plants belonging to 45 families and 47 genera were identified in the district. Majorities (47.37% were collected from wild. Most of the plants (94.23% were reportedly used to treat human diseases. The most frequently used plant parts were leaves (40.38%, followed by fruits (23.08% and roots (17.31%. Local people depend on both dry and fresh remedies. The administration routes were oral (57.69%, dermal (25.00%, nasal (11.54 % and anal (5.77%. The preference ranking showed that Lantana camara was the most important species in treating diarrhea followed by Vernonia amygdalin indicating high utility value of the species in the community. The results revealed existence of diverse medicinal plants and indigenous knowledge in the study area. Therefore, documenting medicinal plants and associated indigenous knowledge can be used as a basis for developing management plans for conservation and sustainable use of medicinal plants in the area.

  7. BIOCHEMICAL ANALYSIS OF MULBERRY ASSOCIATED WITH INTERCROPPING OF MEDICINAL PLANTS UNDER TEMPERATE CLIMATIC CONDITIONSBIOCHEMICAL ANALYSIS OF MULBERRY ASSOCIATED WITH INTERCROPPING OF MEDICINAL PLANTS UNDER TEMPERATE CLIMATIC CONDITIONS

    Directory of Open Access Journals (Sweden)

    M.S. Rathore

    2012-08-01

    Full Text Available The Kashmir valley represents temperate climatic conditions and is known for its bivoltine sericulture. The sericulture in the region however, sustains on tree type of plants. Majority of sericulturists in this traditional area have taken up mulberry cultivation on small land holdings as a life sustaining occupation. Other farmers with more land have taken up it as subsidiary occupation. Mulberry is facing stiff competition from other economic crops. In order to make the mulberry cultivation more profitable and sustainable, intercrops can be practiced with them. Medicinal plants like Lavendula officinalis, Atropa belladonna and Echinacea purpurea are important source of alkaloids and essential oils, which have huge demand in pharmaceutical industry. The wider spacing available in the tree type of plantation of mulberry facilitates the cultivation of these medicinal plants as an intercrop. The present paper focuses on utilization of medicinal plants as an intercrop with mulberry to generate an additional income to the progressive farmers as the biochemical studies shows that there is no significant impact on mulberry leaf quality and soil health.

  8. Traditional ethno-botanical uses of medicinal plants from coastal areas of Pakistan

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    Muhammad Qasim

    2014-01-01

    Full Text Available Objective: To document the traditional uses of wild plants as medicine by the villagers along the coastal highway from Karachi to Uthal. Methods: Information presented in this research was gathered from the local people using an integrated approach of floral collections, discussions with the elderly people and traditional medicinal practitioners using semi-structured questionnaire. Results: Ethno-medicinal surveys indicated the medicinal importance of 54 plant species from 27 families in the targeted area. Majority of the plants (54% from this coastal plant diversity were xerophytes followed by halophytes/xero-halophytes (40% and glycophytes (6%. The most important uses included gastrointestinal diseases, pain killer, arthritis, skin and sexual disorders, asthma and expectorant. The above-ground parts of plants i.e. leaf, stem and fruit/seed as decoction are used most commonly to cure 23 ailments but root was also used in some cases. Conclusions: This study helps in documenting therapeutic uses of herbal remedies with new phyto-medicinal claim and it is hoped that it will lead to detailed chemical and pharmacological evaluations. This may also lead to a discovery of novel bioactive compounds for food and pharmaceutical industries.

  9. GERMPLASM EVALUATION OF MEDICINAL AND AROMATIC PLANTS IN HIGHLAND BALOCHISTAN, PAKISTAN

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    ASLAM GILL

    2008-08-01

    Full Text Available Research studies are carried out for cultivation potential of medicinal and aromatic plants [Thyme, Oregano, Rosemary, Sage (belonging to the family Lamiaceae] in Balochistan. The species studied showed good adaptability in cold and dry area and production potential in highland Balochistan. A medicinal herb garden was also established at Arid Zone Research Centre, Quetta with more than 60 potential medicinal and aromatic plants. This germplasm category includes culinary and herbal teas (Thymus vulgaris, Matricaria recutita, Ocimum basilicum, Mentha piperita, Rosmarinus officinalis, Cymbopogon citrates, Artemisia drancunculus, Origanum majorana, Origanum vulgare. Aromatic plants (Lavandula angustifolia, Lavandula stoechas, Rosmarinus officinalis and medicinal plants (Tanacetum parthenium, Hyssopus officinalis, Pimpinella anisum, Achillea celifolium, Achillea millefolium, Borago officinalis, Salvia officinalis, Oenothera biennis, Crocus sativus. Available germplasm of annually sown crops like (Foeniculum vulgare, Carum copticum, Linum usitatissimum, Anethunm sowa and Nigella sativa, Cuminum cyminum were also evaluated and characterized for morphological description and registration with the Federal Seed Registration and Certification Department. These crops have also been introduced among the farming communities in different agro-ecological zones of Balochistan. The results indicate that medicinal and aromatic plants have great potential for commercial scale cultivation in Balochistan subject to provision of better and sustainable marketing avenues.

  10. Propagação vegetativa de liamba, planta medicinal Vegetative propagation of liamba, a medicinal plant

    OpenAIRE

    Maria de Fátima B Coelho; Sandra Sely S Maia; Andreya K de Oliveira; Francisco Ésio P Diógenes; Silvio Roberto F Soares

    2011-01-01

    A liamba (Vitex agnus castus L.) é utilizada no Brasil como medicinal e apresenta compostos com estrutura química semelhante à progesterona. Visando avaliar a propagação vegetativa de liamba foram conduzidos dois experimentos. O primeiro, com estacas da parte aérea com 20 cm de comprimento, sem folhas e classificadas em dois grupos: apical e basal. As estacas tiveram a espessura padronizada em 3 a 5 mm de diâmetro e 40 unidades de cada tipo foram colocadas em sacolas de polietileno (10 x 30 c...

  11. Ethnopharmacology in Dublin: surveys on the medicinal plants use profile

    Directory of Open Access Journals (Sweden)

    Francis Cunningham

    2011-10-01

    Full Text Available This study aimed to examine the use of natural products as medicines in the greater Dublin area, Ireland. A field study was carried out on eighteen natural health stores; store assistants were interviewed and asked questions from a previously prepared questionnaire. Results were evaluated and a picture could be drawn about the use of natural products in Dublin. Questions asked included best sellers, new products on the market, common prescribers, ailments for which product is requested. Results indicated that as much as 60% of customers requests specific products were advice from staff. Nutritionists accounted for approximately one third of the medical profession that prescribed products for sale in health stores. The survey also examined common medicinal products requested which were not available without prescription. St. John's Wort and Gingko biloba were the most requested. Undoubtly, there is a revival to searching for natural alternatives for the treatment of diseases with no medical advice.

  12. Activities of Some Nigerian Medicinal Plants against Aedes aegypti

    OpenAIRE

    Adeleke Clement Adebajo; Funmilayo Gladys Famuyiwa; Juliet Donatus John; Ekemini Sunday Idem; Adebowale Olusoji Adeoye

    2012-01-01

    Extracts and constituents of medicinal plants have proven to be biodegradable, had low mammalian toxicity and induction of resistance, and comparable activities to the standard drugs. Therefore, methanolic extracts of some plants that are termite resistant or used ethnomedically as antimalarial and febrifuge were evaluated for activities against 4th-instar larvae of Aedes aegypti. A 61 % of these plants with these properties demonstrated larvicidal ac...

  13. Assessment of Anti-Quorum Sensing Activity for Some Ornamental and Medicinal Plants Native to Egypt

    OpenAIRE

    Zaki, Ahmed A; Shaaban, Mona I.; Hashish, Nadia E.; Amer, Mohamed A.; Lahloub, Mohamed-Farid

    2012-01-01

    This study investigated the effects of some plant extracts on the bacterial communication system, expressed as quorum sensing (QS) activity. Quorum sensing has a directly proportional effect on the amount of certain compounds, such as pigments, produced by the bacteria. Alcohol extracts of 23 ornamental and medicinal plants were tested for anti-QS activity by the Chromobacterium violaceum assay using the agar cup diffusion method. The screening revealed the anti-QS activity of six plants; nam...

  14. Analysis of benzoic and cinnamic acid derivatives of some medicinal plants in Serbia

    OpenAIRE

    ?ur?evi? L.; Gaji? Gordana; Jari? Snežana; Kosti? Olga; Mitrovi? Miroslava; Pavlovi? P.

    2013-01-01

    Natural phenolics, which are ubiquitously distributed in plants, have been reported as functional factors in phytotherapy. We have examined phenolic compounds in the leaves and inflorescences of five significant medicinal plants of different plant families: Salvia officinalis (Lamiaceae); Achillea clypeolata (Asteraceae); Nymphaea alba (Nymphaeaceae); Rumex acetosella (Polygonaceae) and Allium ursinum (Alliaceae). The examined species were rich in total phenolics (up to 30.88 mg/g dry w...

  15. Ethnopharmacological Assessment of Medicinal Plants Used against Livestock Infections by the People Living around Indus River

    OpenAIRE

    Mussarat, Sakina; Amber, Rahila; Tariq, Akash; Adnan, Muhammad; AbdElsalam, Naser M.; Ullah, Riaz; Bibi, Roqaia

    2014-01-01

    The present study was aimed to document detailed ethnopharmacological knowledge of medicinal plants against livestock infections of an unexplored remote region of Pakistan. Semistructured questionnaires were used for data collection. Total 43 plants belonging to 26 families were found to be used in ethnoveterinary practices. Seeds (29%) were found to be the most frequent plant part used followed by leaves (22%). Ethnoveterinary recipes were mostly prepared in the form of decoction and powderi...

  16. Medicinal Potential of Poisonous Plants of Tehsil Kahuta from District Rawalpindi, Pakistan

    OpenAIRE

    Sohail Jamil Qureshi; Sofia Bano; Taj Mohammad; Mir Ajab Khan

    2001-01-01

    Medicinal potential of some poisonous plant was studied from Kahuta Rawalpindi district. Calotropis procera is a remedy for asthma, leprosy and skin diseases. Convolvulus arvensis is mild poisonous plant. It is an excellent remedy for skin diseases and is also used for washing hair to remove dandruff. Oil of Ricinus communis is useful in constipation in children and the plant is used as an antiseptic. Root of Euphorbia helioscopia is used as an anthelmintic. Tribulus terrestris is also a mild...

  17. Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants

    OpenAIRE

    Fariba Sharififar; Payam Khazaeli; Narguess Alli; Elham Talebian; Raheleh Zarehshahi; Shivasadat Amiri

    2012-01-01

    Aim: Four medicinal plants of Trigonella foenum-graecum, Zhumeria majdae, Achillea wilhelsii and Viola tricolor are traditionally used in Iran as analgesic and for treatment of inflammatory disorders. At the present atudy, the antinociceptive and anti-inflammatory effects of these plants have been studied. Methods: The antinociceptive and anti-inflammatory activity of methanol extracts of tested plants were evaluated using hot-plate and carrageenan-induced edema methods respectively. Th...

  18. Screening of some traditionally used medicinal plants for potential antibacterial activity

    OpenAIRE

    Parekh Jigna; Karathia Nehal; Chanda Sumitra

    2006-01-01

    In the present work an attempt has been made to carry out screening for the preliminary antibacterial activity of different plants used in Indian folk medicine. The aim of the study was to select an active plant extract which may be useful in developing new lead compounds to combat deadly diseases. Twelve plants were selected for preliminary screening for their antibacterial potentiality, viz., Abutilon indicum L., Acorous calamus L., Ammania baccifera L., Argyrea nervosa Burm. F., B...

  19. A SURVEY OF MEDICINALLY IMPORTANT PLANTS IN AROUND SRIVILLIPUTTUR TALUK, VIRUDHUNAGAR DISTRICT, TAMILNADU

    OpenAIRE

    Pandiarajan G

    2011-01-01

    The Survey was carried out in the remote villages in and around in the Western Ghats of Srivilliputtur Taluk, Virudhunagar District, Tamil Nadu. Most of the Plants are traditionally used by the people for their day to day life. There are 44 plant species belonging to from 22 families of medicinally important plants were identified and their uses are described. Among the species, Ennichostemma littorale, Achyranthus aspera,, Ficus bengalensis, Leucus aspera, Ocimum sanctum, Phyllantus amarus,...

  20. MEDICINAL PROPERTIES OF MANGROVE PLANTS – AN OVERVIEW

    OpenAIRE

    Revathi P*, T Jeyaseelan Senthinath, P Thirumalaikolundusubramanian and N Prabhu

    2013-01-01

    Perhaps the most important role of mangroves is that they protect vulnerable coastlines from wave action because they hold the soil together and prevent coastal erosion. Mangroves shield inland areas during storms and minimize damage. For example, learning from the 2005 tsunami in Asia, there were no deaths in the areas which had mangrove forests, compared to those areas without, which suffered massive causalities. Many species in the mangrove forest have medicinal value and it has been prove...

  1. Medicinal Plants used for Dogs in Trinidad and Tobago

    OpenAIRE

    Lans, C.; Harper, T.; Georges, K.; Bridgewater, K.

    2000-01-01

    This paper documents ethnoveterinary medicines used to treat dogs in Trinidad and Tobago. In 1995, a 4-stage process was used to conduct the research and document the ethnoveterinary practices. Twenty-eight ethnoveterinary respondents were identified using the school-essay method, which is a modified rapid rural appraisal (RRA) technique. Semi-structured interviews were held with these respondents as well as with 30 veterinarians, 27 extension officers and 19 animal-health assistants and/or a...

  2. Antimicrobial and antioxidant activities of Cortex Magnoliae Officinalis and some other medicinal plants commonly used in South-East Asia

    OpenAIRE

    Weng Wanyu; Saw Constance LL; Cheah Emily LC; Chan Lai; Heng Paul WS

    2008-01-01

    Abstract Background Eight medicinal plants were tested for their antimicrobial and antioxidant activities. Different extraction methods were also tested for their effects on the bioactivities of the medicinal plants. Methods Eight plants, namely Herba Polygonis Hydropiperis (Laliaocao), Folium Murraya Koenigii (Jialiye), Rhizoma Arachis Hypogea (Huashenggen), Herba Houttuyniae (Yuxingcao), Epipremnum pinnatum (Pashulong), Rhizoma Typhonium Flagelliforme (Laoshuyu), Cortex Magnoliae Officinali...

  3. Advanced development in analysis of phytochemicals from medicine and food dual purposes plants used in China.

    Science.gov (United States)

    Zhao, Jing; Lv, Guang-Ping; Chen, Yi-Wen; Li, Shao-Ping

    2011-10-21

    The concept of "Let food be thy medicine and medicine be thy food" was widely accepted for thousand years. It is now well known that some foods and food components have beneficial physiological and psychological effects. In China, the Ministry of Health of the People's Republic of China announced 87 items of materials, including 81 plants, could be used as both medicine and food. Increasing consumer demand for safety and health benefits, it is of critical importance to have high-quality and comprehensive data on bioactive compounds (phytochemicals) in these materials. In this review, we summarized the advanced development (2006-2010) in analysis of phytochemicals from medicine and food dual purposes plants (MFDPP) used in China. PMID:21733522

  4. ANTI-INFLAMMATORY ACTIVITY OF SOME TRADITIONAL MEDICINAL PLANTS

    OpenAIRE

    R. K. Singh; Joshi, V. K.; Gambhir, S.S.

    1998-01-01

    The ethanol extract of roots, fruits and roots of solanum indicum and saccharum munja respectively and water soluble resin of commiphora myrrha were studied for antiinflammatory activity against carrageenin induced oedema in rats, the significant antiinflammatory activity were found in former two plants will slight anti inflammatory activity was observed in latter plant.

  5. Anti-inflammatory activity of some traditional medicinal plants.

    Science.gov (United States)

    Singh, R K; Joshi, V K; Gambhir, S S

    1998-10-01

    The ethanol extract of roots, fruits and roots of solanum indicum and saccharum munja respectively and water soluble resin of commiphora myrrha were studied for antiinflammatory activity against carrageenin induced oedema in rats, the significant antiinflammatory activity were found in former two plants will slight anti inflammatory activity was observed in latter plant. PMID:22556885

  6. Anthocyanins: analysis and distribution in selected medicinal plants

    Science.gov (United States)

    Anthocyanins are water soluble plant secondary metabolites responsible for the blue, purple, and red color of many plant tissues. They have been shown to be strong antioxidants, and may exert a wide range of health benefits through antioxidant or other mechanisms. Anthocyanins occur primarily as g...

  7. Modulation of diabetes-mellitus-induced male reproductive dysfunctions in experimental animal models with medicinal plants

    OpenAIRE

    Jain, Gyan Chand; Jangir, Ram Niwas

    2014-01-01

    Today diabetes mellitus has emerged as a major healthcare problem throughout the world. It has recently broken the age barrier and has been diagnosed in younger people also. Sustained hyperglycemia is associated with many complications including male reproductive dysfunctions and infertility. Numerous medicinal plants have been used for the management of the diabetes mellitus in various traditional system of medicine and in folklore worldwide as they are a rich source of bioactive phytoconsti...

  8. Characterization of phenolic compounds in flowers of wild medicinal plants from Northeastern Portugal.

    OpenAIRE

    Barros, Lillian; Dueñas, Montserrat; Carvalho, Ana Maria; Ferreira, Isabel C. F. R.; Santos-Buelga, Celestino

    2012-01-01

    Crataegus monogyna, Cytisus multiflorus, Malva sylvestris and Sambucus nigra have been used as important medicinal plants in the Iberian Peninsula since a long time ago, and are claimed to have various health benefits. This study aimed to determine the phenolic profile and composition of wild medicinal flowers of those species. The analysis was performed by HPLC-DAD-ESI/MS. Flavonoids, and particularly flavonols and flavones, were the main groups in almost all the studied samples. C. multiflo...

  9. Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine

    OpenAIRE

    Javier Palazón; Rosa M. Cusido; Mercedes Bonfill; Elisabeth Moyano; Mohammad Hossein Mirjalili

    2010-01-01

    Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and indigenous medicine for over 3,000 years. In view of its varied therapeutic potential, it has also been the subject of considerable modern scientific attention. The major chemical constituents of the Withania genus, the withanolides, are a group of naturally occurring C28-steroidal lactone triterpenoids built on an intact or rearranged ergostane framework, in which C-22 and C...

  10. Integrative Approach to Analyze Biodiversity and Anti-Inflammatory Bioactivity of Wedelia Medicinal Plants

    OpenAIRE

    Lin, Wen-Ching; Wen, Chih-Chun; Chen, Yung-Hsiang; Hsiao, Pei-Wen; Liao, Jiunn-Wang; Peng, Ching-I; Yang, Ning-Sun

    2015-01-01

    For the development of “medical foods” and/or botanical drugs as defined USA FDA, clear and systemic characterizations of the taxonomy, index phytochemical components, and the functional or medicinal bioactivities of the reputed or candidate medicinal plant are needed. In this study, we used an integrative approach, including macroscopic and microscopic examination, marker gene analysis, and chemical fingerprinting, to authenticate and validate various species/varieties of Wedelia, a reputed ...

  11. Uranium and thorium nuclides series determined in medicinal plants commonly used in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Silva, P.; Francisconi, L.; Damatto, S. [IPEN/CNEN-SP, Sao Paulo (Brazil)

    2014-07-01

    In recent years the study of medicinal plants has become the focus of ever more extensive research all over the world due to their diversity and potential as source of medicinal products. According to the World Health Organization approximately 80% of world population makes use of medicinal herbs due to their believed therapeutic action. Besides being used as medicine, medicinal plants are also largely used as dietary supplements. The presence of radionuclides in plants constitutes one of the main pathways for their transfer to man. The amount of radioactive nuclides from U and Th series in edible vegetables are relatively well known since they have been the main concern of research conducted worldwide. Medicinal plants, on the other hand, have been neglected in these studies, possibly because the ingestion of radioactive material through their consumption has not been recognized or was considered insignificant. The objective of the present study was to determine the content of natural radionuclides from {sup 238}U and {sup 232}Th series in 25 species of medicinal plants used in Brazil, both as medicine and as dietary supplement. The medicinal plant samples were obtained in specialized pharmacies and drugstores. The raw plant and their extracts, produced as recommended by the National Agency for Sanitary Vigilance, were analyzed by Instrumental Neutron Activation Analyses for the determination of U and Th and by Total Alpha and Beta Counting after Radiochemical Separation for determination of {sup 226}Ra, {sup 228}Ra and {sup 210}Pb. In the raw plants the activity concentrations varied from 0,08 Bq kg{sup -1} to 8,0 Bq kg{sup -1} for thorium, from < LID to 22 Bq kg{sup -1} for uranium, from 1,8 Bq kg{sup -1} to 12 Bq kg{sup -1} for {sup 226}Ra, from 33 Bq kg{sup -1} to 74 Bq kg{sup -1} for {sup 228}Ra and from 10 Bq kg{sup -1} to 120 Bq kg{sup -1} for {sup 210}Pb. In the extracts, the activity concentrations varied from 9 mBq kg{sup -1} to 137 mBq kg{sup -1} for Th and 145 mBq kg{sup -1} to 580 mBq kg{sup -1} for U. Document available in abstract form only. (authors)

  12. Screening of Antibacterial Activities of Essential Oils from Selected Medicinal Plants

    International Nuclear Information System (INIS)

    Essential oils were extracted from the five medicinal plants (Syzygium aromaticum Linn, Cinnamoum tamala. Nees, Piper betle. Linn, Ocimum sanctum, Clausena exacavata Burn) by steam distillation method and percolation method with petroleum ether. These plants do not contain cyanogenic glycosides according to phytochemical tests. Essential oils from these plants were also tested on antimicrobial activity by agar well diffusion method. It was observed that essential oils extracted from these five plants have various effects on Gram-positive and Gram-negative bacteria and fungus. Among them, essential oils of Syzygium aromaticum possess the highest antimicrobial activity aganist all test organisms. B. pumalis and Calbican are the most susceptible to the five plants.

  13. Rediscovering Medicinal Plants' Potential with OMICS: Microsatellite Survey in Expressed Sequence Tags of Eleven Traditional Plants with Potent Antidiabetic Properties

    Science.gov (United States)

    Sahu, Jagajjit; Sen, Priyabrata; Choudhury, Manabendra Dutta; Dehury, Budheswar; Barooah, Madhumita; Modi, Mahendra Kumar

    2014-01-01

    Abstract Herbal medicines and traditionally used medicinal plants present an untapped potential for novel molecular target discovery using systems science and OMICS biotechnology driven strategies. Since up to 40% of the world's poor people have no access to government health services, traditional and folk medicines are often the only therapeutics available to them. In this vein, North East (NE) India is recognized for its rich bioresources. As part of the Indo-Burma hotspot, it is regarded as an epicenter of biodiversity for several plants having myriad traditional uses, including medicinal use. However, the improvement of these valuable bioresources through molecular breeding strategies, for example, using genic microsatellites or Simple Sequence Repeats (SSRs) or Expressed Sequence Tags (ESTs)-derived SSRs has not been fully utilized in large scale to date. In this study, we identified a total of 47,700 microsatellites from 109,609 ESTs of 11 medicinal plants (pineapple, papaya, noyontara, bitter orange, bermuda brass, ratalu, barbados nut, mango, mulberry, lotus, and guduchi) having proven antidiabetic properties. A total of 58,159 primer pairs were designed for the non-redundant 8060 SSR-positive ESTs and putative functions were assigned to 4483 unique contigs. Among the identified microsatellites, excluding mononucleotide repeats, di-/trinucleotides are predominant, among which repeat motifs of AG/CT and AAG/CTT were most abundant. Similarity search of SSR containing ESTs and antidiabetic gene sequences revealed 11 microsatellites linked to antidiabetic genes in five plants. GO term enrichment analysis revealed a total of 80 enriched GO terms widely distributed in 53 biological processes, 17 molecular functions, and 10 cellular components associated with the 11 markers. The present study therefore provides concrete insights into the frequency and distribution of SSRs in important medicinal resources. The microsatellite markers reported here markedly add to the genetic stock for cross transferability in these plants and the literature on biomarkers and novel drug discovery for common chronic diseases such as diabetes. PMID:24802971

  14. Medicinal plants potential and use by pastoral and agro-pastoral communities in Erer Valley of Babile Wereda, Eastern Ethiopia

    OpenAIRE

    Belayneh Anteneh; Asfaw Zemede; Demissew Sebsebe; Bussa Negussie F

    2012-01-01

    Abstract Background Ethiopian plants have shown remarkably effective medicinal values for many human and livestock ailments. Some research results are found on medicinal plants of the south, south west, central, north and north western parts of Ethiopia. However, there is lack of data that quantitatively assesses the resource potential and the indigenous knowledge on use and management of medicinal plants in eastern Ethiopia. The main thrust of the present ethnobotanical study centres around ...

  15. Medicinal and local food plants in the south of Alava (Basque Country, Spain)

    Science.gov (United States)

    Alarc?n, Roc?o; Pardo-de-Santayana, Manuel; Priestley, Caroline; Morales, Ramón; Heinrich, Michael

    2015-01-01

    Ethnobotanical relevance Medicinal and food plants in the Basque Country are an integral part of a fast changing culture. With a distinct tradition and language, this region of Europe provides an important example demonstrating the changing role of local and traditional knowledge in industrial countries. As other Mediterranean regions it preserves a rich heritage of using plants as medicine and food, offering a unique opportunity for studying the medicine food interface in an ethnopharmacological context. Therefore, the key goal of this study has been to contribute to an understanding of local and traditional plant usage, to evaluate their uses as food and medicine as well as to critically assess the role of these plants in the south of the Basque Country contributing to an understanding of how foods and medicines are used. Methods A mixed methods approach, including participant observation; open and semi structured interviews was used. Ethnobotanical field work included 183 people, ages ranged from 24 to 98 years old with a majority being between 70 and 80 years old (mean age 71) from 31 towns of three different regions. The basic interview was a one-to-one meeting, which often included field walking and collection of samples as directed by the informants. 700 voucher specimens (most of them with duplicates) were collected for the data obtained. Using SPSS version 20 the gathered information was processed and the replies of the different informants were subsequently organised in variables like medicine and food plants, part of the plants used, forms of preparations, zones preferred for collecting these plants. The data were analysed based on the frequency of records. This type of approach allows us to understand the way the informant’s categorize the species, and how these categories are distributed along the sample. In order to analyse the data three main categories of use were distinguished: Medicine (M), Food (F) and an intermediate Health-Food (H-F). The three categories were divided in 27 subcategories (common uses). Results and discussion The informants recognise and use a total of 184 species from 49 families. During interviews, 5658 individual use-reports were collected relating to three use-categories – as medicines, food and health-food. The two main groups with almost the same number of species each are health-food (75 species) and (locally gathered) food only (73), with medicinal uses only (36) being the smallest group. This highlights the important overlap between food and medicines. Overall, three core families were identified (based on the number of use reports and in the number of species): Asteraceae (25 species), Lamiaceae and Rosaceae (24 each). The most frequently reported species are Jasonia glutinosa, Chamaemelum nobile, Prunus spinosa and Quercus ilex subsp. ballota. The most important general use-subcategories are as raw vegetables (27.43% of the use-reports and including 81 species), infusions (14.74%/42) and gastrointestinal (12.53%/42). Conceptually foods and medicines are clearly distinguished but the intermediate group of health foods is more ambiguous. Conclusion Food and medicinal uses of plants are culturally closely linked. A wide range of plants are known and many still used. The analysis shows that the Basques use a wide range of species which are typical for Western European cultures. In comparison to other studies in the Mediterranean countries there are many similarities in the uses of different families, species of plants and their use and preparations. Some of these plants are key Mediterranean species, often used for a multitude of uses as food and medicine. PMID:26481607

  16. Evaluation of the In Vitro Antiplasmodial, Antileishmanial, and Antitrypanosomal Activity of Medicinal Plants Used in Saudi and Yemeni Traditional Medicine

    Science.gov (United States)

    Mothana, Ramzi A.; Al-Musayeib, Nawal M.; Al-Ajmi, Mohamed F.; Cos, Paul; Maes, Louis

    2014-01-01

    The antiplasmodial, antileishmanial, and antitrypanosomal activity of twenty-five medicinal plants distributed in Saudi Arabia and Yemen was evaluated. The plants were extracted with methanol and screened in vitro against erythrocytic schizonts of Plasmodium falciparum, intracellular amastigotes of Leishmania infantum and Trypanosoma cruzi, and free trypomastigotes of T. brucei. To assess selectivity, cytotoxicity was determined on MRC-5 cells. Criteria for activity were an IC50 9.6 and >5.9). Interesting activity against L. infantum was obtained with Verbascum bottae (IC50 of 3.2??g/mL, SI 10.2) and Solanum glabratum (IC50 8.1??g/mL, SI 3.4). The extracts of C. penicillata, Leucas virgata, Loranthus regularis, and V. bottae exhibited moderate activity against T. brucei (IC50 8.5, 8.1, 8.3, and 2.3??g/mL; SI > 7.6, 7.7, 4.3, and >14.1). These results partly support the traditional use of some of the selected medicinal plants and warrant further investigations into the putative active constituents. PMID:24963330

  17. In vitro Antiplasmodial Activity of Some Medicinal Plants Used in Folk Medicine in Burkina Faso Against Malaria

    Directory of Open Access Journals (Sweden)

    Cheikna Zongo

    2011-05-01

    Full Text Available The aim of this study was to evaluate the in vitro antiplasmodial activities of four plants used in traditional medicine. Hydroethanolic extract, hydroacetonic extract and aqueous extract of Mitragyna inermis (Willd. O. Kuntze (Rubiaceae, Combretum sericeum G. Don (Combretaceae, Alternanthera pungens H.B. and K (Amaranthaceae and Ampelocissus grantii (Baker Planch (Vitaceae have been tested in vitro against chloroquine-resistant strain (K1 and chloroquine-sensitve strain (3D7 of Plasmodium falciparum using pLDH assay. Aqueous extracts exhibited the best results against K1 with the 50% inhibitory concentration (IC50 values of 0.54±0.18, 1.72±0.99, 1.54±0.04 ?g/mL for respectively, M. inermis leaves, C. sericeum leaves and whole plant of A. pungens. Hydroethanolic extract from the leaves of M. inermis gave also IC50 value of 0.87±0.10 ?g/mL with 3D7. Extracts showed antiplasmodial activity against both chloroquine-sensitive and chloroquine-resistant P. falciparum strains. Our study justifies the use of these plants in traditional medicine and leads to further investigations.

  18. The Assessment of Pesticides Residues in Some Organic Cultivated and Wild-Collected Medicinal Plants in Albania

    Directory of Open Access Journals (Sweden)

    FERDI BRAHUSHI

    2014-06-01

    Full Text Available Pesticide residues in environment are found in soil, water and plants due to the extensive use of pesticides for agricultural purposes. The residues of pesticides in medicinal plants are of high concern as they are toxic for human life since these plants are used for medicinal purposes. The objective of current study was to estimate the presence of pesticide residues in some organic cultivated and wild-collected medicinal plants in Albania during the years 2010–2013. The determination of pesticides residues in medicinal plants was achieved by using extraction of plant material with organic solvent, clean up procedure and followed by detection with chromatography techniques. Among the detected pesticide residuesin the wild–collected plants as Malva sylvestris, Fragaria vesca, Bellis perennis were DDT, Dimethoat, Pirimiphos-methyl, Chlorpyriphos-ethyl, Carbendazim/Benomyl, Acetamiprid and Diphenylamine. Whereas in the cultivated medicinal plants as Calendula officinalis, Centaurea cyani, Salvia officinalis, Sideritis raeseri, the most common detected pesticide residues were Dimethoat, Chlorpyriphos, Pirimiphos-methyl, DDT and Carbendazim. The presence of pesticides in medicinal plant is related to the past use of pesticides as DDT and actual use of pesticides like Dimethoat, Pirimiphos-methyl, Chlorpyriphos, Acetamiprid, etc. Therefore, the quality of medicinal plants can be evaluated through estimation of pesticides residues in medicinal plants and comparison of the obtained values with acceptable limit values.

  19. ANTIOXIDANT, CYTOTOXIC PROPERTIES AND PHYTOCHEMICAL SCREENING OF TWO LEBANESE MEDICINAL PLANTS

    Directory of Open Access Journals (Sweden)

    Rammal Hassan

    2013-06-01

    Full Text Available Nowadays herbal medicine presents a significant adjuvant tool for hard treatment, especially in the case of cancer where modern medicine has access to traditional medicine to deprive the patient of the side effects of therapeutic approaches such as surgery and chemotherapy. Thus, Lebanese 10452 km2 are so rich in medicinal plants such as Eryngium creticum L. and Euphorbia macroclada Boiss that are traditionally used in the treatment of various diseases (leukemia, asthma, skin diseases, antidote to snake venom, tumors, etc.. To fully realize the importance of these two Lebanese plants, we tried at first to study the phytochemistry of three extracts (aqueous, methanolic and ethyl acetate from fresh leaves and stems of both plants. In a second step, the antioxidant capacity of these three extracts from the two parts of the fresh plants using spectrophotometric analysis has been evaluated and their cytotoxicity on the MCF7 breast cancer cell line by the XTT Cell viability technique has been studied. Our results showed that both leaves and stems of these two plants contain alkaloid, tannin, coumarin, saponin, flavonoid, polyphenol and reducing sugars in different concentrations. Moreover, both leaves and stems have exerted an antioxidant activity that may be due to their phenolic content and they have also inhibited the growth of cancer cell line from 68 % to 72 %. These results showed that both plants can be considered as a good source of natural products that can be used in the prevention of several diseases.

  20. The role of medicinal plants in the treatment of diabetes: a systematic review

    Science.gov (United States)

    Kooti, Wesam; Farokhipour, Maryam; Asadzadeh, Zahra; Ashtary-Larky, Damoon; Asadi-Samani, Majid

    2016-01-01

    Introduction Diabetes is a serious metabolic disorder and plenty of medical plants are used in traditional medicines to treat diabetes. These plants have no side effects and many existing medicines are derived from the plants. The purpose of this systematic review is to study diabetes and to summarize the available treatments for this disease, focusing especially on herbal medicine. Methods Required papers about diabetes and effective plants were searched from the databases, including Science direct, PubMed, Wiley, Scopus, and Springer. Keywords in this study are ”medicinal plants”, “diabetes”, “symptom”, “herbal”, and “treatment”. Out of the 490 collected articles (published in the period between 1995 and 2015), 450 were excluded due to non-relevance or lack of access to the original article. Results Diabetes is mainly due to oxidative stress and an increase in reactive oxygen species that can have major effects. Many plants contain different natural antioxidants, in particular tannins, flavonoids, C and E vitamins that have the ability to maintain β-cells performance and decrease glucose levels in the blood. Conclusion According to published results, it can be said that medical plants are more affordable and have less side effects compared synthetic drugs, and are more effective in treatment of diabetes mellitus.

  1. Effects of rare earth elements on growth and metabolism of medicinal plants

    Directory of Open Access Journals (Sweden)

    Chunhong Zhang

    2013-02-01

    Full Text Available The rare earth elements (REEs are a set of 17 chemical elements. They include the lanthanide series from lanthanum (La to lutetium (Lu, scandium (Sc, and yttrium (Y in the periodic table. Although REEs are used widely in industry and agriculture in China for a long time, there has been increasing interest in application of REEs to medicinal plants in recent years. In this paper, we summarize researches in the past few decades regarding the effects of REEs on the germination of seeds, the growth of roots, total biomass, and the production of its secondary metabolites, as well as their effects on the absorption of minerals and metals by medicinal plants. By compilation and analysis of these data, we found that REEs have promoting effects at low concentrations and negative effects at comparatively high concentrations. However, most studies focused only on a few REEs, i.e., La, cerium (Ce, neodymium (Nd and europium (Eu, and they made main emphasis on their effects on regulation of secondary metabolism in tissue-cultured plants, rather than cultivated medicinal plants. Advanced research should be invested regarding on the effects of REEs on yields of cultivated plants, specifically medicinal plants.

  2. Antimicrobial activity of some medicinal plants used by herbalists in Eastern province, Kenya.

    Science.gov (United States)

    Kareru, P G; Gachanja, A N; Keriko, J M; Kenji, G M

    2007-01-01

    The aqueous extracts from medicinal plants commonly used by herbalists in Mbeere, and Embu districts of Eastern province, Kenya, were tested for their inhibitory activity against three selected strains of bacteria. All the selected plant extracts (infusions: 1.0 g sample in 100 ml water) investigated showed activity against Escherichia coli with inhibition zone diameters ranging from 5.8-18.0 mm. Terminalia brownii gave the largest inhibition zones against E. coli and Staphylococcus aureus. Vernonia lasiopus and Tithonia diversifolia were inactive to S. aureus and Bacillus subtilis, respectively. Eighteen and sixteen plants showed sensitivity of greater than 10 mm against S. aureus and B. subtilis, respectively. All control discs gave zones of inhibition of 12-24 mm, which were larger than those of the extracts. The present study validated the use of the selected medicinal plants by the herbalists in the treatment of bacterial ailments caused by the strains of bacteria investigated. Medicinal plants used for non-bacterial diseases also exhibited sensitivity towards bacterial strains tested. This implied they could be used as multi-purpose medicinal plants. PMID:20162055

  3. Medicinal plants growing in the Judea region: network approach for searching potential therapeutic targets

    Directory of Open Access Journals (Sweden)

    Arie Budovsky

    2012-09-01

    Full Text Available Plants growing in the Judea region are widely used in traditional medicine of the Levant region. Nevertheless, they have not so far been sufficiently analyzed and their medicinal potential has not been evaluated. This study is the first attempt to fill the gap in the knowledge of the plants growing in the region. Comprehensive data mining of online botanical databases and peer-reviewed scientific literature including ethno-pharmacological surveys from the Levant region was applied to compile a full list of plants growing in the Judea region, with the focus on their medicinal applications. Around 1300 plants growing in the Judea region were identified. Of them, 25% have medicinal applications which were analyzed in this study. Screening for chemical-protein interactions, together with the network-based analysis of potential targets, will facilitate discovery and therapeutic applications of the Judea region plants. Such an approach could also be applied as an integrative platform for further searching the potential therapeutic targets of plants growing in other regions of the world.

  4. Common plants of medicinal values in kolams of Adilabad district, Andhra Pradesh

    Directory of Open Access Journals (Sweden)

    Rao VLN

    2012-01-01

    Full Text Available Background: Common plants of medicinal values in Kolams are used as ethnomedical practices for various ailments and diseases inhabiting the Utnoor division of Adilabad district, Andhra Pradesh, India. Aim: This paper provides data on 31 medicinal plants used by Kolams for curing various ailments along with their local names, method of preparation, mode of administration and use. Materials and Methods: Our collections of ethnomedicinal plant specimens from this area were deposited in the Andhra University Herbarium (AUH, Visakhapatnam, Andhra Pradesh, India. Detailed interviews were conducted on four ethnomedical specialists drawn from the six study villages of the selected two Jainoor and Narnoor mandals of Utnoor division of Adilabad district, Andhra Pradesh. Results: The ethno-medical system among Kolam is quite diverse and the local knowledge is used mostly in primary health care. The vast traditional knowledge present among Kolam is mostly attributed to their cultural framework. Conclusion: The present study revealed the situation with regard to use common plants of medicinal values in the study area. 31 plant species from Utnoor division of Adilabad district in Andhra Pradesh were used to treat 57 different ailments and diseases. Among these plant species only few species are used to treat more than one disease. Medicinal pastes are prepared from stem, root, and leaves to treat diseases by the tribal people.

  5. Use and valuation of native and introduced medicinal plant species in Campo Hermoso and Zetaquira, Boyacá, Colombia

    DEFF Research Database (Denmark)

    Cadena-Gonzalez, Ana Lucia; Sørensen, Marten; Theilade, Ida

    2013-01-01

    Background: Medicinal plant species contribute significantly to folk medicine in Colombia. However, few local studies have investigated whether species used are introduced or native and whether there is a difference in importance of native and introduced medicinal plant species. The aim of the...... present study was to describe the use of medicinal plants within two municipalities, Campo Hermoso and Zetaquira, both in the department of Boyaca Colombia and to assess the importance of native and introduced plants to healers, amateur healers and local people. As local healers including amateur healers...

  6. Ethnoveterinary medicinal plants: Preparation and application methods by traditional healers in selected districts of southern Ethiopia

    Directory of Open Access Journals (Sweden)

    Gebremedhin Romha Eshetu

    2015-05-01

    Full Text Available Aim: The aim was to document the ethnoveterinary medicinal plants, their preparation, and application methods used by traditional healers in treating different animal diseases, in four districts with different culture and languages in southern Ethiopia. Materials and Methods: Information of ethnoveterinary medicinal plants was obtained through in-depth direct interview with the local healers and field observations. A descriptive statistics was used to analyze the reported ethnoveterinary medicinal plants and associated indigenous knowledge. The informant consensus factor (ICF was calculated for each category of diseases to identify the agreements of the informants on the reported cures. Preference ranking was used to assess the degree of effectiveness of certain medicinal plants against most prevalent animal diseases in the area. Results: The healers had a very high intention to keep their traditional knowledge secrete and none of them was ready to transfer their knowledge either freely or on incentive bases to other people; they need to convey their knowledge only to their selected scions after getting very old. A total of 49 plant species used to treat 26 animal ailments were botanically classified and distributed into 34 families. The most commonly used plant parts for remedy preparations were leaves (38.8%, followed by whole roots (20.4%. Calpurnia aurea (Ait. Benth was the most preferred effective treatment against external parasite and skin problem, which is the most prevalent disease with the highest ICF (0.68. Conclusion: The study suggests that the community of the study districts depend largely on ethnoveterinary medicinal plants for the treatment of different animal ailments though the healers have a very high intention to keep their traditional knowledge secrete. Commonly reported plant species need to be tested for their antimicrobial activities in vitro and validated their active ingredients in order to recommend effective preparations and treatments to this community.

  7. Trade potential and conservation issues of medicinal plants in district Swat, Pakistan

    International Nuclear Information System (INIS)

    Use of medicinal plants for various health disorders is a common practice especially in rural areas. Poor economic condition and lack of modern health care facilities in remote areas are the major reasons for adopting traditional medicine. Mingora is considered as the main center of trade of medicinal plants not only of Swat but of the entire Hindu Kush-Himalayan Region of Pakistan. The city was analyzed for the trade potential of local medicinal plants. The present study reported trade and marketing profile of 99 species collected locally and sold in the national and international markets. A total of 99 taxa were collected belonging to 55 families and 80 genera. Helvellaceae was at the top among the largest families with 9 taxa, followed by Asteraceae and Solanacea with 8 and 6 taxa respectively. Among the life form Chamaephyte was at the top with 27 taxa (27.27%), followed by Hemicryptophyte, Phanerophyte, Therophyte, Geophyte and Parasite with 25 (25.25%), 24 (24.24%), 17 (20.20%), 2 (2.02%) and 1 taxa (1.01%), respectively. Market analysis revealed that annual production and its share to the market was 8.056 and 6.644 million kg during the years 2004-2005 and 2005-2006 whereas, it gave rise to the circulation of Rs. 4475.00 and Rs. 5084.70 millions, respectively. Thus quantity traded decreased due to the unsustainable collection in the wild, while amount circulated increased due to rise in price kg/sup -1/ as a result of increased demand from the national and international market. According to an estimate approximately 99,840 individuals (i.e. 8% of the total population of Swat) are associated with the collection or trade of these important medicinal plants in the valley. The study also revealed that availability of medicinal plants decreased day by day and this process is continued for the last two decades. According to local elders, most of the medicinal plants reported were abundant in the vicinities some 20 years back. However, their population was drastically decreased due to over exploitation, extension in agricultural lands, increased market pressure, lack of alternate earning opportunities in the area and unsustainable harvesting methods etc. All these threats have affected the population size of these medicinal plants in the wild. Therefore, early measures for the management of medicinal flora for sustaining its market supply and there by securing livelihood opportunities of rural communities are needed on urgent basis. (author)

  8. Phytochemical and biological activities of four wild medicinal plants.

    Science.gov (United States)

    Shad, Anwar Ali; Ahmad, Shabir; Ullah, Riaz; AbdEl-Salam, Naser M; Fouad, H; Ur Rehman, Najeeb; Hussain, Hidayat; Saeed, Wajid

    2014-01-01

    The fruits of four wild plants, namely, Capparis decidua, Ficus carica, Syzygium cumini, and Ziziphus jujuba, are separately used as traditional dietary and remedial agents in remote areas of Khyber Pakhtunkhwa, Pakistan. The results of our study on these four plants revealed that the examined fruits were a valuable source of nutraceuticals and exhibited good level of antimicrobial activity. The fruits of these four investigated plants are promising source of polyphenols, flavonoids, alkaloids, terpenoids, and saponins. These four plants' fruits are good sources of iron, zinc, copper, manganese, selenium, and chromium. It was also observed that these fruits are potential source of antioxidant agent and the possible reason could be that these samples had good amount of phytochemicals. Hence, the proper propagation, conservation, and chemical investigation are recommended so that these fruits should be incorporated for the eradication of food and health related problems. PMID:25374941

  9. Ecological Properties of the Medicinal Plant-Helleborus orientalis Lam.

    Directory of Open Access Journals (Sweden)

    Mahmut Kilinc

    2005-01-01

    Full Text Available In this study, nutrient concentrations (N, P and K in above and below ground parts of Helleborus orientalis Lam. which has several medicinal properties were examined during vegetative and generative growth periods. There were significant differences between two growth periods in different parts of H. orientalis in terms of N and K concentrations. We have only found statistically significant differences between the studied localities, in terms of K concentrations. There were no significant differences with respect to soil factors except K and organic matter concentrations of the studied localities. Our findings are supported the vernal dam hypothesis.

  10. COMPARATIVE ASSESSMENT OF TOTAL PHENOLIC CONTENT IN SELECTED MEDICINAL PLANTS

    OpenAIRE

    C. E. Johnson; Oladeinde, F. O.; A.M. Kinyua; Michelin, R.; Makinde, J.M.; Jaiyesimi, A.A.; Mbiti, W.N.; Kamau, G.N.; Kofi-Tsekpo, W.M.; Pramanik, S.; Williams, A.; Kennedy, A.; Bronner, Y; Clarke, K.; Fofonoff, P.

    2008-01-01

    This study was to compare the total phenolic (TP) content in extracts from eleven plant materials collected at different geographical locations in Kenya, Nigeria, and USA. These plants have been selected because the majority of them are highly pigmented, from yellow to purple, and would therefore have economic value in industries for producing antioxidants and surfactants. Two of them were collected from the industrial and domestic waste outlets. Each analysis was achieved using the Folin-Cio...

  11. MEDICINAL PLANTS USED AS AN ANTIDIABETIC DRUG IN PHARMACEUTICAL INDUSTRY AND THEIR CONSERVATION: AN OVERVIEW

    Directory of Open Access Journals (Sweden)

    Shankar Murthy K.

    2012-10-01

    Full Text Available This article attempts to review the literature and the emerging policy issues on Antidiabetic plants for pharmaceutical usage. Also provides a brief review of different plants using in the traditional system for the treatment of diabetes since ancient times. Plants such as Allium cepa, Anacardium occidentale, Andrographic paniculata, Momordica charantia, Azadirachtha indica, Brassica oleraccia, Cinnamomum tamala and Withania sominifera are commonly using as remedy for diabetes. There is an increasing demand for the herbal medicines for diabetic ailments and many plant drugs from Ayurvedic system are being explored. The biological activities from various clinical and preclinical studies have been included. Some of the acclaimed valuation works done in the last few years have been considered for this purpose. Conservation of biodiversity based on the benefits of medicinal plants and the traditional knowledge can be considered as good starting point for effective conservation of Antidiabetic plants, which requires accurate and up-to date information on the status of medicinal plant populations, detailed area-specific study, landscape valuation, extent and nature of plant use by local communities.

  12. Natural radioactivity levels of some medicinal plants commonly used in Ghana.

    Science.gov (United States)

    Tettey-Larbi, Lordford; Darko, Emmanuel Ofori; Schandorf, Cyril; Appiah, Alfred Ampomah

    2013-12-01

    Natural radioactivity levels in some selected medicinal plants commonly used in Ghana from the Centre for Scientific Research into Plant Medicine were investigated to determine the activity concentration and the annual committed effective dose due to naturally occurring radionuclides of (238)U, (232)Th and (40)K. The activity concentration was determined using gamma-ray spectrometry. The results of the analysis indicated an average activity concentration of (238)U, (232)Th and (40)K in the medicinal plants to be 31.8±2.8 Bq kg(-1), 56.2±2.3 Bq kg(-1) and 839.8±11.9 Bq kg(-1) respectively. Khaya ivorensis recorded the highest activity concentration of (238)U and (232)Th while Lippia multiflora recorded the highest activity concentrations of (40)K. The total annual committed effective doses ranged from 0.026±0.001 to 0.042±0.002 mSv a(-1) with an average value of 0.035±0.001 mSv a(-1). The average annual committed effective dose due to ingestion of the natural radionuclides in the medicinal plant samples were far below the world average annual committed effective dose of 0.3 mSv a(-1) for ingestion of natural radionuclides provided in UNSCEAR 2000 report. Therefore, the radiological hazard associated with intake of the natural radionuclides in the medicinal plants is insignificant. The results provide baseline values which may be useful in establishing rules and regulations relating to radiation protection as well as developing standards and guidelines for the use of medicinal or herbal plants to the appropriate authorities. PMID:23641323

  13. Evaluation of Phytochemical Constituents of Indian Medicinal Plant Hydnocarpus alpina WIGHT.

    Directory of Open Access Journals (Sweden)

    M. Dhanasekaran*, S. Karuppusamy, M. Annadurai, K.M.Rajasekaran

    2013-09-01

    Full Text Available Hydnocarpus alpina WIGHT. is a evergreen forest plant. It is an endemic plant to western ghats of India. Severallocal names are available based on distribution among the state in india that is Torathi (kanada, Maravetti(Malayalam, attuchankalai (tamil, kastel (hindi. This tree has very appreciated value in the aspect of medicine. Ithas anti-larvicidal, anti-feedant, anti-microbial and etc. It has the medicinal properties due to the presence of itssignificant chemical constituents. In this paper revealed that the IR spectrum and chemical constituents which arepresent in different solvents (chloroform, pet.ether, ethanol, water.

  14. Studies on antifungal activity and elemental composition of the medicinal plant trianthema pentendra linn

    International Nuclear Information System (INIS)

    Antifungal activity of crude solvent and aqueous extracts of the medicinal plant, Trianthema pentendra Linn., against the dermatophytic fungi, Aspergillus niger, Aspergillus flavus, Paecilomyces varioti, Microsporum gypseum and Trichophyton rubrum revealed that ethanol and aqueous extracts were the most effective antifungal agents as compared to methanol, chloroform and ethyl acetate extracts. Some basic elements, Al, Ca, Cu, Fe, Mg, Mn, P, S and Zn were also determined in the medicinal plant, T. pentendra, using atomic absorption spectrophotometry and U.V spectrophotometry. T. pentendra contained considerable amount of elements which have therapeutic effects in skin diseases. (author)

  15. SOME IMPORTANT MEDICINAL PLANTS USED IN THE TREATMENT OF ASTHMA - A REVIEW.

    OpenAIRE

    Sheela Kumar; V. K. Agnihotri; Sunita Thakur; Anita Verma; Saxena, R. C.; Soni, Kapil K.

    2012-01-01

    Ayurveda, Siddha, Unani and Folk (Tribal) medicines are the major systems of indigenous medicines. Over three-quarters of the world population relies mainly on plants and plant extracts for health care. Unlike many diseases, which can be attributed to the life style of modern man, asthma is an ancient illness. Mast cells play an important role in some type of allergic reaction because the antibody that causes the allergic reaction that is Ig E have the mast cells which contains about a thousa...

  16. Screening of Allelopathic Activity of Eleven Thai Medicinal Plants on Seedling Growth of Five Test Plant Species

    OpenAIRE

    H. Kato-Noguchi; P. Piyatida

    2010-01-01

    Eleven species of Thai medicinal plants, namely Rhinacanthus nasutus (L.) Kurz, Clitoria ternatea L., Mammea siamensis Kosterm., Centella asiatica (L.) Urban, Thunbergia lauriflolia Linn., Piper sarmentosum Roxb., Hibiscus sabdariffa L., Moringa oleifera Lam., Tinospora tuberculata Beume, Tiliacora triandra (Colebr.) Diels. and Amomum krervanh Pierre ex. Gagnep. were evaluated their allelopathic potentials against cress (Lepidium sativum L.), lettuce (Lactuca sativa L.), alfalfa (Medicago s...

  17. Biological activities of commonly used medicinal plants from ghazi brotha, attock district

    International Nuclear Information System (INIS)

    Medicinal plants are important natural source of possibly secure drugs. They have been playing a significant role in mitigating human miseries by contributing herbal medicines in the primary health care systems of remote areas. About 70% population of rural and remote areas depends on folklore and traditional medicines to cure various ailments. The traditional medicines have gained much popularity due to the high cost and adverse effects of allopathic medicines which encouraged manufacturers of Greco-Arab and Ayurvedic systems of medicines to fuse their orthodox medicines with local traditional medicines in order to spread health coverage at a reasonable rate. Keeping in view the importance of ethnobotanical survey the current survey was carried out in Attock District, Punjab which comes under the Rawalpindi Division. The region has rural values of old civilizations and customs. The inhabitants of this area have their own trends for a village site, house, family, childbirth, death ceremonies, cultural functions, festivals and socio-religious belief. The ladies are more energetic and laborious as compared to gents. There is a lack of communication with current civilization which has kept them closer to nature from where they fulfill many of their daily needs. The inhabitants of the area are very close to natural flora, both in their habitat and livelihood. People of the area have speculative observations of nature and by communicating with other people of their culture, they discover the inherent knowledge of the local plants. As a result they gain indigenous knowledge, generation after generation. Plants and their derivatives available from the local area are utilized for many purposes such as food, fodder, medicine, veterinary medicines, timbers, households, oilseeds and also for socio-religious and various other purposes. In this way important medicinal plants are collected throughout the year for advertising, personal and entire community use. Due to random and excessive use of antimicrobial drugs in the treatment of contagious diseases, pathogenic bacteria have developed great resistance against prevailing antibiotics. Multi-drug resistant strains of bacteria generally spread in hospitals and are being isolated from population acquired infections. All this has resulted in severe consequences such as failure of treatment. Hence, it was imperative to explore natural products as an alternative to synthetic antimicrobial agents. (author)

  18. Comprehensive Evidence-Based Assessment and Prioritization of Potential Antidiabetic Medicinal Plants: A Case Study from Canadian Eastern James Bay Cree Traditional Medicine

    OpenAIRE

    Andrew Kawapit; Eliza Mamianskum; John Petagumskum; Johnny Husky Swallow; Mary Jolly; Charlotte Husky Swallow; Charlie Etapp; Jimmy George; Louise Etapp; Rene Coon Come; Josephine Diamond; Emma Coon Come; Alain Cuerrier; Timothy Johns; Steffany Bennett

    2012-01-01

    Canadian Aboriginals, like others globally, suffer from disproportionately high rates of diabetes. A comprehensive evidence-based approach was therefore developed to study potential antidiabetic medicinal plants stemming from Canadian Aboriginal Traditional Medicine to provide culturally adapted complementary and alternative treatment options. Key elements of pathophysiology of diabetes and of related contemporary drug therapy are presented to highlight relevant cellular and molecular targets...

  19. In vitro cytotoxic screening of selected Saudi medicinal plants.

    Science.gov (United States)

    Almehdar, Hussein; Abdallah, Hossam M; Osman, Abdel-Moneim M; Abdel-Sattar, Essam A

    2012-04-01

    Many natural products from plants have been identified to exert anticancer activity. It might be expected to be a challenge to look at the Saudi plants in order to discover new sources for new molecules which may have anticancer activity. The methanolic extracts of forty species of plants traditionally used in Saudi Arabia for the treatment of a variety of diseases were tested in vitro for their potential anticancer activity on different human cancer cell lines. The cytotoxic activity of the methanolic extracts of the tested plants were determined using three human cancer cell lines, namely, breast cancer (MCF7), hepatocellular carcinoma (HEPG2), and cervix cancer (HELA) cells. In addition, human normal melanocyte (HFB4) was used as normal nonmalignant cells. Sulforhodamine B colorimetric assay was used to evaluate the in vitro cytotoxic activity of the different extracts. The growth inhibition of 50% (IC(50)) for each extract was calculated from the optical density of treated and untreated cells. Doxorubicin, a broad-spectrum anticancer drug, was used as the positive control. Nine plant extracts were chosen for further fractionation based on their activity and availability. Interesting cytotoxic activity was observed for Hypoestes forskaolii, Withania somnifera, Solanum glabratum, Adenium obesum, Pistacia vera oleoresin, Caralluma quadrangula, Eulophia petersii, Phragmanthera austroarabica, and Asparagus officinalis. Other extracts showed poor activity. PMID:21953271

  20. Hairy root induction and plant regeneration of medicinal plant Dracocephalum kotschyi.

    Science.gov (United States)

    Sharafi, Ali; Sohi, Haleh Hashemi; Azadi, Pejman; Sharafi, Ata Allah

    2014-04-01

    An efficient hairy root induction system for an important endangered medicinal plant, Dracocephalum kotschyi, was developed through Agrobacterium rhizogenes-mediated transformation by modifying the co-cultivation medium using five bacterial strains, A4, ATCC15834, LBA9402, MSU440, and A13 (MAFF-02-10266). A drastic increase in transformation frequency was observed when a Murashige and Skoog medium lacking NH4NO3 KH2PO4, KNO3 and CaCl2 was used, resulting in hairy root induction frequencies of 52.3 %, 69.6 %, 48.6 %, 89.0 %, and 80.0 % by A4, A13, LBA9402, MSU440, and ATCC15834 strains, respectively. For shoot induction, hairy roots and unorganized tumors induced by strain ATCC15834 were placed on an MS media supplemented with 0.1, 0.25, 0.5, and 1 mg/l BA plus 0.1 mg/l NAA. The high frequency of shoot regeneration and number of shoot were obtained in the medium containing 0.25 mg/l BA and 0.1 mg/l NAA. Root induction occurred from the base of regenerated shoots on the MS medium supplemented with 0.5 mg/l IBA after 10 days. PMID:24757330

  1. Identification of medicinal plants of Urmia for treatment of gastrointestinal disorders

    Scientific Electronic Library Online (English)

    Mahmoud, Bahmani; Arman, Zargaran; Mahmoud, Rafieian-Kopaei.

    2014-08-01

    Full Text Available The gastrointestinal tract is one of the most important organs of the human body and is vulnerable to different diseases. Available drugs often have low efficacy or are associated with many adverse effects. Therefore, alternative drugs are necessary to treat gastrointestinal complications. This stud [...] y intended to identify medicinal plants in Urmia, Iran, that can affect common gastrointestinal disorders and diseases. Data was collected from public resources via interviews and questionnaires applied from April to June 2013. Herbarium specimens were collected from the region and authenticated by a botanist. A total of 41 indigenous medicinal plants from the Urmia region, belonging to twenty families, have a traditional medicinal role in the treatment of parasitic and infectious diseases, diarrhea, reflux, gastroenteritis, peptic ulcer, constipation, bloating, among other gastrointestinal tract disorders. Analysis showed that most plants affecting the gastrointestinal tract belonged in the Asteraceae family (24%). The most used part of the plants was the seed at 17%. Decoction at 65% was the most popular form of treatment used. Some of the medicinal plants discussed in this article have new implications presented for the first time. Pharmacological studies on the therapeutic effects of the indigenous plants mentioned in this study are necessary in order to investigate their claimed clinical effects and the use of their effective compounds to produce natural and useful drugs. Currently, there is no data on the herbal plants used to treat gastrointestinal disorders in northwestern Iran. Therefore, these findings are important for the management of gastrointestinal disorders and to conduct future studies on traditional medicine for drug development.

  2. Pollution Based Study of Heavy Metals in Some Selected Medicinal Plants by Dry Digestion Method

    Directory of Open Access Journals (Sweden)

    Abdul Niaz

    2013-03-01

    Full Text Available Study of heavy metals including Iron (Fe, Nickel (Ni, Manganese( Mn, Zinc (Zn, Copper (Cu, Cadmium (Cd, Chromium (Cr and Lead (Pb in four selected medicinal plants Capparis spinosa, Peganum harmala , Rhazya stricta and Tamarix articulata collected from polluted and unpolluted areas of Karak, Khyber Pakhtunkhwa Pakistan was performed by atomic absorption spectrophotometer. Dry Ashingmethod was adopted for sample preparation. In general the concentration level of heavy metals in the selected plants from polluted area was found to decrease in the order of Fe > Zn > Mn > Cu >Pb > Ni > Cr > Cd, and the same order was also found in unpolluted area. In polluted area Iron was found high 48.76 mg/kg in leaves ofCapparis spinosa while least level (Below detection level was that of Cadmium and in unpolluted area the level of iron was high 54.94 mg/kg in roots of Rhazya stricta while least concentration was that of Cd 0.02 mg/kg in leaves of Peganum harmala. These medicinal plants were selected for our investigation having in mind their extensive use in traditional medicine for various ailments by local physicians in the area from where these plants were collected. Monitoring such medicinal plants for heavy metals is a supreme importance in protecting the Public from the adverse and hazardous affects of these heavy metals.

  3. SOME IMPORTANT MEDICINAL PLANTS USED IN THE TREATMENT OF ASTHMA - A REVIEW.

    Directory of Open Access Journals (Sweden)

    Sheela Kumar

    2012-10-01

    Full Text Available Ayurveda, Siddha, Unani and Folk (Tribal medicines are the major systems of indigenous medicines. Over three-quarters of the world population relies mainly on plants and plant extracts for health care. Unlike many diseases, which can be attributed to the life style of modern man, asthma is an ancient illness. Mast cells play an important role in some type of allergic reaction because the antibody that causes the allergic reaction that is Ig E have the mast cells which contains about a thousand tiny granules. These granules are loaded with dozens of potent chemicals or mediators, the most powerful in which are histamine and a newly discovered group called leukotrienes. From the present laboratory, there are number of medicinal plants have been reported for antihistaminic/anti-asthmatic activities. Some of them are Achyranthes aspera, Tephrosia purpurea,Dolichos lablab, Eclipta alba, Jasminum sambac, Balanites aegyptiaca, Viscum album, Tridex procumbens, Glycyrrhiza glabra and Cassia fistula. Recently, Soni (2009-2011 has reported 100% inhibition ofLeukotrienes (which cause asthma from the EtoAC fraction of Bacopa monnieri extract. It is suggested that formulation and patent of the reported medicinal plants is mandatory for further use against asthma and if possible, clinical trials should be done of these plants for their appropriate use.

  4. Review on Medicinal Plants used by Local Community of Jodhpur District of Thar Desert

    Directory of Open Access Journals (Sweden)

    B.P. Nagori

    2011-01-01

    Full Text Available The traditional uses of medicinal plants in healthcare practices are providing clues to new areas of research; hence its importance is now well recognized. However, information on the uses of indigenous plants for medicine is not well documented from many rural areas of Rajasthan. Questionnaire surveys, participatory observations and field visits were planned to elicit information on the medicinal plants used by local community of Jodhpur district of Thar desert. The use of 21 plants distributed into 17 families is described. The medicinal plant preparations were applied through different routes of administration like oral, topical or dermal and nasal routes. However, oral application was the highest and most commonly used route of application followed by topical or dermal. Major findings were use of Abrus precatorius for urinary disorders, abortion and contraception; Achyranthes aspera for asthma, cough and gynecological purpose; Acacia catechu as astringent, antidiarrheal, haemostatic and for treatment of skin diseases; Capparis decidua antidiabetic, hypolipidemic, analgesic and anti-inflammatory; Euphorbia caducifolia cutaneous eruption, leucoderma, earache and Ziziphus nummularia as antidiarrheal and anti-infective for skin.

  5. ETHNO MEDICINAL STUDY OF THREATENED PLANTS OF SONITPUR DISTRICT IN ASSAM, NORTH EAST INDIA

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    Das Amar Jyoti

    2013-01-01

    Full Text Available Assam is endowed with a rich wealth of medicinal plants. It has the richest reservoir of plant diversity of India and is one of the hot diversity spots of the world supporting about 50% of India’s biodiversity. Traditional medical practice has been recognized by the World health Organization (WHO as a building block of primary healthcare. Assam has a rich traditional knowledge of folk medicinal practices. But rapid fragmentation of natural habitats and unrestricted exploitation coupled with limited cultivation and insufficient attempts for its replacement has decreased this knowledge day by day. As a result, this wild stock of the medicinal plant species has been markedly depleted with increasing the risk of loosing their genetic diversity and the medicinal quality of these plants remains unknown.Many species are extinct or on the verge of extinction before they are known for their scientific uses. In order to categorize and update the list of threatened species, the International Union for Conservation of Nature and Natural Resources (IUCN has recognized the categories on the basis of geographical range, populations and fragmentation of populations.The present study was carried out in Sonitpur district of Assam for the documentation of ethnomedicinal importance of such threatened plants species.

  6. Medicinal plants used as sedative by ecological farmers from southern rio grande do sul state, brazil

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    Teila Ceolin, Rita Maria Heck, Rosa Lía Barbieri, Andrieli Daiane Zdanski de Souza, Walter Fagundes Rodrigues, Marisa Vanini

    2009-10-01

    Full Text Available Objective: to identify the medicinal plants used as with sedative effects by families of ecological farmers from Southern Rio Grande do Sul State, Brazil. Methods: this is a qualitative study, exploratory and descriptive approach, and the data were collected from January to May 2009. Eight families of farmers were participants which were residents in Pelotas, Morro Redondo, Canguçu and Arroio do Padre cities. This study was approved by the Committee of Ethics in Research of the Medicine Faculty of the Federal University of Pelotas (072/2007. Results: it was found citations of 196 medicinal plants, some native and other exotic, and seven elixirs. From these, twelve plants (Lactuca sativa L., Aloysia gratissima (Gillies & Hook. Tronc., Chamomilla recutita L., Cymbopogon citratus (DC., Aloysia triphylla Royle, Aristolochia cymbifera Mart. & Zucc., Ageratum conyzoides L., Eucalyptus sp., Citrus sinensis (L. Osbeck, Passiflora caerulea L., Melissa officinalis L., Cunila microcephala Benth., and one elixir were mentioned as having soothing effect. Conclusion: the nurse can work in guidelines the use of medicinal plants aimed at health promotion, prevention and treatment of diseases. It is essential the enlargement of the pharmacological studies on plants used by popular knowledge in health care.

  7. Antimicrobial activity of four medicinal plants widely used in Persian folk medicine

    Directory of Open Access Journals (Sweden)

    A. Hamedi

    2015-12-01

    Full Text Available Background and objectives: Commiphora habessinica (O.Berg Engl. (Burseraceae, Boswellia sacra Flueck (Burseraceae, Phoenix dactylifera L. (Arecaceae, and Doronicum glaciale (Wulfen Nyman (Asteraceae are of ethnomedicinal importance in Persian folk medicine and are widely used to treat infectious diseases. The aim of the present study was to investigate the antimicrobial properties of these herbal medicines to prevent misadministration. Methods: Antifungal and antibacterial (Gram-positive and Gram-negative activities of the petroleum ether, dichloromethane and ethanol fractions obtained from oleo-gum-resin of C. habessinica and B. sacra, spathe of P. dactylifera and roots of D. glaciale were evaluated against standard species and clinical antibiotic resistant isolates using broth microdilution method. The fractions were tested at concentrations of 0.5 to 256 µg/mL.Results: The petroleum ether fraction of C. habessinica oleo-gum-resin exhibited the most anti-Candida activity with MIC50 of 0.5-16 µg/mL. The growth of C. glabrata and C. tropicalis was inhibited by the ethanol fraction of C. habessinica oleo-gum-resin with MIC50 of 1-16 ?g/mL. C. glabrata was the most susceptible species. Among the tested fractions, only the petroleum ether fraction of C. habessinica oleo-gum-resin had an inhibitory effect on Aspergillus spp. with a MIC50 of 8-32 µg/mL. None of the fractions exhibited antimicrobial activity against the Gram-positive and Gram-negative bacteria at concentrations of 0.5 to 256 µg/mL. Conclusions: The sensitivity of fungi and bacteria to natural antimicrobials varies widely within species and it is essential to consider the sensitivity of the strains to prevent resistance.

  8. Efforts on conservation and sustainable use of medicinal plants of Pakistan

    International Nuclear Information System (INIS)

    Since the beginning of civilization, and perhaps as early as Neanderthal man, people have used plants as medicine. Evidence indicates that people used plants to cure themselves, e.g. Chinese Emperor (2800 BC); Babylon (1770 BC); Ancient Egypt (1550 BC). Islamic and Indian physicians also wrote many works prior to 1100 AD and the Seals from the Harappan site in Pakistan (2000 BC) also indicate use of plants. New aspects of medicinal plants need to be studied. For example, we should address the question why plant diversity declines, when plants with weedy traits become more abundant. This is consequently followed by, species that have traits permitting their persistence in degraded and species-poor cosystems which are likely to carry high pathogen and vector burdens. Indigenous communities of Pakistan play a vital role in conservation of medicinal plants. Intentionally or unintentionally, people have evolved strategies for doing so in the form of rituals, beliefs and taboos. Various traditional harvesting methods described in one of the study suggest that they were efficient to utilize the natural resources. Our efforts are towards not only providing food security, nutrition and health care to the tribal people, but also to recover, record and diffuse local botanical knowledge and wisdom. (author)

  9. Indigenous knowledge of medicinal plants of Chagharzai valley, district Buner, Pakistan

    International Nuclear Information System (INIS)

    Indigenous knowledge of medicinal plants was recorded during summer 2004, in 22 villages of Chagharzai valley, District Buner. The study revealed 141 plant species belonging to 120 genera and 26 families are being used as medicine. The local people know the prospect and nature of the plant utilization, through personal experiences and ancestral prescriptions. The study also revealed that old aged people particularly women posses strong folk love of medicinal plants in comparison to young people. It was concluded that some plants are used singly while many other are used in combination. Similarly few plant species are used for the treatment of a specific disease, while several other have multiple uses. The plants were mainly used as stomachic, anti-allergic, antineuralgia, vermifuge, narcotic, laxative, anti jaundice, emollient, hypnotic, diuretic, digestive, demulcent, carminative, astringent, aphrodisiac, anti-spasmodic, anti-emetic, anti-diabetic, anthelmentic, anodyne and alterative. The present investigation will help in the preservation of indigenous knowledge of the local people, which is depleting day by day. (author)

  10. Consensus of the 'Malasars' traditional aboriginal knowledge of medicinal plants in the Velliangiri holy hills, India

    Science.gov (United States)

    Ragupathy, Subramanyam; Steven, Newmaster G; Maruthakkutti, Murugesan; Velusamy, Balasubramaniam; Ul-Huda, Muneer M

    2008-01-01

    There are many vanishing cultures that possess a wealth of knowledge on the medicinal utility of plants. The Malasars of Dravidian Tamils are an indigenous society occupying the forests of the Western Ghats, South India. They are known to be exceptional healers and keepers of traditional aboriginal knowledge (TAK) of the flora in the Velliangiri holy hills. In fact, their expertise is well known throughout India as evidenced by the thousands of pilgrims that go to the Velliangiri holy hills for healing every year. Our research is the first detailed study of medicinal plants in India that considers variation in TAK among informants using a quantitative consensus analysis. A total of 95 species belonging to 50 families were identified for medicinal and general health purposes. For each species the botanical name, family, local name, parts used, summary of mode of preparation, administration and curing are provided. The consensus analysis revealed a high level of agreement among the informants usage of a particular plant at a local scale. The average consensus index value of an informant was FIC > 0.71, and over 0.80 for some ailments such as respiratory and jaundice. Some of the more common problems faced by the Malasars were gastrointestinal disorders, respiratory illness, dermatological problems and simple illness such as fever, cough, cold, wounds and bites from poisonous animals. We also discovered several new ethnotaxa that have considerable medicinal utility. This study supports claims that the Malasars possess a rich TAK of medicinal plants and that many aboriginals and mainstream people (pilgrims) utilize medicinal plants of the Velliangiri holy hills. Unfortunately, the younger generation of Malasars are not embracing TAK as they tend to migrate towards lucrative jobs in more developed urban areas. Our research sheds some light on a traditional culture that believes that a healthy lifestyle is founded on a healthy environment and we suggest that TAK such as that of the Malasars may serve toward a global lifestyle of health and environmental sustainability. PMID:18371206

  11. Harnessing the potential clinical use of medicinal plants as anti-diabetic agents

    Directory of Open Access Journals (Sweden)

    Campbell-Tofte JI

    2012-08-01

    Full Text Available Joan IA Campbell-Tofte,1 Per Mølgaard,2 Kaj Winther11Department of Clinical Biochemistry, Frederiksberg University Hospital, Frederiksberg, Denmark; 2Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Copenhagen, DenmarkAbstract: Diabetes is a metabolic disorder arising from complex interactions between multiple genetic and/or environmental factors. The characteristic high blood sugar levels result from either lack of the hormone insulin (type 1 diabetes, T1D, or because body tissues do not respond to the hormone (type 2 diabetes, T2D. T1D patients currently need exogenous insulin for life, while for T2D patients who do not respond to diet and exercise regimes, oral anti-diabetic drugs (OADs and sometimes insulin are administered to help keep their blood glucose as normal as possible. As neither the administration of insulin nor OADs is curative, many patients develop tissue degenerative processes that result in life-threatening diabetes comorbidities. Several surveys of medicinal plants used as anti-diabetic agents amongst different peoples have been published. Some of this interest is driven by the ongoing diabetes pandemic coupled with the inadequacies associated with the current state of-the-art care and management of the syndrome. However, there is a huge cleft between traditional medicine and modern (Western medicine, with the latter understandably demanding meaningful and scientific validation of anecdotal evidence for acceptance of the former. The main problems for clinical evaluation of medicinal plants with promising anti-diabetic properties reside both with the complexity of components of the plant materials and with the lack of full understanding of the diabetes disease etiology. This review is therefore focused on why research activities involving an integration of Systems Biology-based technologies of pharmacogenomics, metabolomics, and bioinformatics with standard clinical data, should be used for cost-effective validation of the safety and anti-diabetic efficacy of promising medicinal plants. The application of such approaches to studying entire mixtures of plant materials will ensure proper elucidation of novel therapies with improved mechanisms of action, as well as facilitate a personalized clinical use of medicinal plants as anti-diabetic agents.Keywords: medicinal plants, anti-diabetes therapy, natural products, systems biology, 'omics technologies, drug discovery

  12. Anti Yeast Activity of Some Plants Used in Traditional Herbal-medicine of Iran

    OpenAIRE

    G. H. Shahidi Bonjar

    2004-01-01

    This is the first report showing the anti-yeast activities of different Iranian plants. Plants used in herbal-medicine were collected from South-East regions of Iran. Methanolic extracts were prepared and evaluated in Agar well-diffusion test against three yeast species of Saccharomyces cerevisiae, Candida albicans and C. utilis. From 48 plant species in 34 families, 26 species in 20 families showed inhibitory effect at least against one yeast species at 20 mg ml ha-1 . Plants with high anti-...

  13. Medicinal Potential of Poisonous Plants of Tehsil Kahuta from District Rawalpindi, Pakistan

    Directory of Open Access Journals (Sweden)

    Sohail Jamil Qureshi

    2001-01-01

    Full Text Available Medicinal potential of some poisonous plant was studied from Kahuta Rawalpindi district. Calotropis procera is a remedy for asthma, leprosy and skin diseases. Convolvulus arvensis is mild poisonous plant. It is an excellent remedy for skin diseases and is also used for washing hair to remove dandruff. Oil of Ricinus communis is useful in constipation in children and the plant is used as an antiseptic. Root of Euphorbia helioscopia is used as an anthelmintic. Tribulus terrestris is also a mild poisonous plant for humans but poisonous for goats. The leaves of Cannabis sativa are antispasmodic, narcotic and sedative.

  14. ABORTIFACIENT ACTIVITY OF A MEDICINAL PLANT “MORINGA OLEIFERA” IN RATS

    OpenAIRE

    Sethi, N; Nath, D; Shukla, S.C.; Dyal, R

    1988-01-01

    Dried powder of leaf extract of common Indian plant Moringa Oleifera of Moringaceae family was tested experimentally in albino rats in our laboratory for its antifertility activity. Cant per cent abortifacient activity was found when administered orally in aqueous solution at dose of 175 mg/kg body weight daily to Charles foster strain albino rats from days 5-10 post mated.

  15. Antimicrobial activity of medicinal plants against oral microorganisms

    OpenAIRE

    More, Garland; Tshikalange, T.E. (Thilivhali Emmanuel); Lall, Namrita; Botha, Francien Susanna; Meyer, J.J.M. (Jacobus Johannes Marion)

    2008-01-01

    Ethanol extracts of eight plant species used traditionally in South Africa for the treatment of oral diseases were investigated for in vitro antimicrobial activity against oral pathogens namely Actinobacillus actinomycetemcomitans, Actinomyces naeslundii, Actinomyces israelii, Candida albicans, Porphyromonus gingivalis, Privotella intermedia and Streptococcus mutans using the disk diffusion method. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of ethanol ...

  16. Antithrombin activity of medicinal plants from central Florida.

    Science.gov (United States)

    Chistokhodova, Natalya; Nguyen, Chi; Calvino, Tony; Kachirskaia, Ioulia; Cunningham, Glenn; Howard Miles, D

    2002-07-01

    A chromogenic bioassay was utilized to determine the antithrombin activity of methylene chloride and methanol extracts prepared from 30 plants of central Florida. Extracts of Ardisia crenata, Tetrapanax papyriferus, Lagerstroemia indica, Callistemon lanceolatus, Antigonon Leptopus, Magnolia virginiana, and Myrica cerifera demonstrated activity of 80% or higher in this bioassay system. PMID:12065163

  17. MEDICINAL PLANTS USED BY TRIBALS OF PANCHMAHALS DISTRICT, GUJARAT

    OpenAIRE

    Painuli, R.M.; Maheshwari, J.K.

    1994-01-01

    An ethnobotanical survey was conduction in 20 tribal villages of Panchamahals district of Gujarat, inhabited by various tribal groups. The present communication records 36 plant species belongings to 34 genera and 27 families used by them in the treatment of various diseases and ailments.

  18. Evaluation for antidiabetic activity in selected medicinal plants used in Malaysian traditional medicine for the treatment of diabetes

    International Nuclear Information System (INIS)

    Aqueous extracts of three medicinal plants used in Malaysian traditional medicine for the treatment of diabetes were investigated. The nuts of Areca cathecu, leaves of Lagerstroemia speciosa and Ficus deltoidea were each extracted by boiling in distilled water. The aqueous extracts were filtered and the filtrates were then spray dried. Their biological evaluation was conducted to determine their blood glucose lowering effect in normoglycaemic and alloxan-induced diabetic rats. Commercially available antidiabetic drug, glybenclamide was used as positive control. Toxicity of the extracts was carried out using the brine shrimp lethality assay and in vivo acute toxicity test in rats. Aqueous extracts of all the plants studied showed significant reduction in blood glucose level up to 50% in rats over a period of 3 to 4 weeks. The largest reduction in blood glucose levels was exhibited by the aqueous extracts of the Lagestroemia speciosa, followed by the Ficus deltoidea and Areca cathecu. There was no evidence of toxicity of the extracts against the brine shrimp (up to 4,000 ?g/ml) and in rats (up to 0.2% body weight). (Author)

  19. Anti-quorum sensing activity of medicinal plants in southern Florida.

    Science.gov (United States)

    Adonizio, Allison L; Downum, Kelsey; Bennett, Bradley C; Mathee, Kalai

    2006-05-24

    Bacterial intercellular communication, or quorum sensing (QS), controls the pathogenesis of many medically important organisms. Anti-QS compounds are known to exist in marine algae and have the ability to attenuate bacterial pathogenicity. We hypothesized that terrestrial plants traditionally used as medicines may also produce anti-QS compounds. To test this hypothesis, 50 medicinal plants from southern Florida were screened for anti-QS activity using two biomonitor strains, Chromobacterium violaceum and Agrobacterium tumefaciens. Of these plants, six showed QS inhibition: Conocarpus erectus L. (Combretaceae), Chamaecyce hypericifolia (L.) Millsp. (Euphorbiaceae), Callistemon viminalis (Sol. ex Gaertn.) G. Don (Myrtaceae), Bucida burceras L. (Combretaceae), Tetrazygia bicolor (Mill.) Cogn. (Melastomataceae), and Quercus virginiana Mill. (Fagaceae). This study introduces not only a new mode of action and possible validation for traditional plant use, but also a potentially new therapeutic direction for the treatment of bacterial infections. PMID:16406418

  20. Acorus calamus (The Healing Plant): a review on its medicinal potential, micropropagation and conservation.

    Science.gov (United States)

    Sharma, Vikas; Singh, Isha; Chaudhary, Priyanka

    2014-01-01

    Acorus calamus L., a tall, perennial, grass-like monocot plant from the Acoraceae family, is a well-known plant in Indian traditional medicines for centuries. It is a highly valued herb as it acts as a rejuvenator for brain and nervous system. It is a main medhya drug, which has the property of improving the memory power and intellect. Rhizomes of the plant are widely used in the treatment of number of ailments such as epilepsy, mental ailments, chronic diarrhoea, dysentery, fever, abdominal tumours, kidney and liver troubles, and rheumatism. A. calamus leaves, rhizomes and its essential oil possess many biological activities such as antispasmodic, carminative and are compiled in a simple approach in this review. This review presents a pragmatic description that deals with chemical constituents, toxicology, ethnobotany and pharmacological properties of A. calamus for easy and better understanding of the outstanding medicinal potential of this very special plant and sirens for its conservation. PMID:24824923

  1. Medicinal plants used in Rondônia, Western Amazon, Brazil

    Directory of Open Access Journals (Sweden)

    M.R.A. Santos

    2014-01-01

    Full Text Available This study refers to the use of medicinal plants by populations in the Western Amazon and provides information that can be used in phytochemical studies. It draws upon the traditional knowledge regarding the use of medicinal plants in five regions of the state of Rondônia, in the Brazilian Amazon, focusing on native species. The field research was carried out in five municipalities of the state of Rondônia: Ariquemes, Buritis, Candeias do Jamari, Cujubim and Itapoa do Oeste, characterized by primary economic sectors: agriculture, cattle farming, plant extraction and mineral exploration. Structured interviews were applied to 227 persons chosen because of their prestige in the communities in relation to the knowledge and use of medicinal plants, identifying the therapeutic purpose, parts of the plant used and methods of preparation. The species were taxonomically identified. The ethnobotanic knowledge (inferred by the number of uses of medicinal plants per person was correlated with the Brazilian region of origin, age, and gender of the interviewees. According to the collected data, 34 botanical families and 53 native species were identified. Of the 53 species, only 7 occur exclusively in the Amazon Forest: Theobroma grandiflorum (Willd. ex Spreng. K. Schum., Psidium densicomum Mart. ex DC, Piper cavalcantei Yunck., Pilocarpus microphyllus Stapf ex Wardlew., Euterpe oleracea Mart., Croton cajucara Benth., Baccharis altimontana G. Heiden. The most common disorders treated with the plants were kidney problems, influenza, generalized infections and inflammations, malaria and high blood pressure. Leaves were the most used parts in preparations. Barks, fruits, roots, flowers, stems, seeds, oils, buds, tubercles, and rhizomes were also mentioned. Thirteen forms of preparations were recorded, and infusion and decoction were the most used. Syrups, juices, flour, sap, oil and parts of the plant blended with milk, honey and coffee or flamed, macerated and in the form of poultice, were also found. Persons from the Southeast region had more information compared with persons from the other regions; persons in the age groups between 50-59, 60-69 and 70-79 had more information in comparison with the other age groups; and the female interviewees mentioned significantly more uses of medicinal plants than the male ones. The relatively small number of native Amazon species identified can be the result of the loss of knowledge about medicinal plants in the Amazon because of internal migration, extinction of local indigenous groups, increasing urbanization and consequent globalization of the lifestyles.

  2. An ethnomedicinal survey of cucurbitaceae family plants used in the folk medicinal practices of Bangladesh 1

    Directory of Open Access Journals (Sweden)

    Mohammed Rahmatullah

    2012-01-01

    Full Text Available Background: The Cucurbitaceae family comprising about 125 genera and 960 species is a family that is further characterized by commonly having five-angled stems and coiled tendrils and is also known as gourd family of flowering plants. Plant species belonging to this family have a worldwide distribution, but most species can be found in tropical and subtropical countries. A number of the plants belonging to this family have reported important pharmacological activities. Cucurbitaceae family plants are also in use in the folk medicinal system of Bangladesh-a traditional medicinal system, which mainly relies on medicinal plants for treatment of diverse ailments. Aims: Since folk medicinal practitioners form the first tier of primary health care in Bangladesh, the objective of this study was to conduct ethnomedicinal surveys among 75 folk medicinal practitioners (Kavirajes practicing among the mainstream Bengali-speaking population of randomly selected 75 villages in 64 districts of Bangladesh and 8 tribal practitioners (1 each from 8 major indigenous communities or tribes, namely, Bede, Chakma, Garo, Khasia, Marma, Murong, Santal, and Tripura of the country. Materials and Methods: Surveys were carried out with the help of a semi-structured questionnaire and the guided field-walk method. Results: It was observed that the folk and tribal medicinal practitioners use a total of 19 Cucurbitaceae family species for treatment of ailments such as dysentery, diabetes, edema, skin disorders, leukoderma, hypertension, jaundice, typhoid, spleen disorders, respiratory problems, leprosy, rheumatoid arthritis, chicken pox, and cancer. The 19 species of Cucurbitaceae family plants in use were Benincasa hispida, Bryonopsis laciniosa, Citrullus colocynthis, Citrullus lanatu, Coccinia grandis, Cucumis melo, Cucumis sativus, Cucurbita maxima, Cucurbita pepo, Hodgsonia macrocarpa, Lagenaria vulgaris, Luffa acutangula, Luffa cylindrica, Momordica charantia, Momordica cochinchinensis, Trichosanthes anguina, Trichosanthes cordata, Trichosanthes dioica, and Trichosanthes kirilowii. The review of the available scientific literature showed that the use of a number of the above-mentioned plants in folk medicine can be validated based on their reported pharmacological activity studies. Conclusion: Taken together, the plants present excellent potential for further scientific studies, which may result in discovery of novel compounds of therapeutic interest.

  3. Ethnobotanical study of medicinal plants used by people in Zegie Peninsula, Northwestern Ethiopia

    Directory of Open Access Journals (Sweden)

    Giday Mirutse

    2007-03-01

    Full Text Available Abstract An ethnobotanical study was conducted from October 2005 to June 2006 to investigate the uses of medicinal plants by people in Zegie Peninsula, northwestern Ethiopia. Information was gathered from 200 people: 70 female and 130 males, using semistructured questionnaire. Of which, six were male local healers. The informants, except the healers, were selected randomly and no appointment was made prior to the visits. Informant consensus factor (ICF for category of aliments and the fidelity level (FL of the medicinal plants were determined. Sixty-seven medicinal plants used as a cure for 52 aliments were documented. They are distributed across 42 families and 64 genera. The most frequently utilized plant part was the underground part (root/rhizome/bulb (42%. The largest number of remedies was used to treat gastrointestinal disorder and parasites infections (22.8% followed by external injuries and parasites infections (22.1%. The administration routes are oral (51.4%, external (38.6%, nasal (7.9%, and ear (2.1%. The medicinal plants that were presumed to be effective in treating a certain category of disease, such as 'mich' and febrile diseases (0.80 had higher ICF values. This probably indicates a high incidence of these types of diseases in the region, possibly due to the poor socio-economic and sanitary conditions of this people. The medicinal plants that are widely used by the local people or used as a remedy for a specific aliment have higher FL values (Carissa spinarum, Clausena anisata, Acokanthera schimperi, Calpurnia aurea, Ficus thonningii, and Cyphostemma junceum than those that are less popular or used to treat more than one type of aliments (Plumbago zeylanicum, Dorstenia barnimiana.

  4. Use of medicinal plants in different composts for yield improvement of various strains of oyster mushroom

    International Nuclear Information System (INIS)

    Different of concentration of four medicinal plants viz., Eucalyptus camaldulensis, Azadirachta indica, Citrus lemon, Cymbopogon marginatus were investigated for the effect of certain active components in their parts, capable of increasing mushroom yield and controlling mushrooms pathogenic microbes which cause great loss in mushroom yield. Four strains of Oyster mushroom were selected on the basis of their well mycelial growth on MEA. For selection of best compost simple composts were also prepared without any medicinal plant products i.e., cotton, wheat, paddy straw. Corn stover composts and cotton compost gave the maximum yield. The dried leaves of the Citrus lemons, lemon grass and Neem cake (dried) were crushed, and the sawdust of the logs of Eucalyptus were incorporated with different doses of 2%, 3%, 4%, 5% w/w of substrates with cotton substrate before compost fermentation. Each of the compost bag having specific medicinal plant product with specific concentration were spawned with selected four strains of Oyster mushroom i.e., two local strain Pleurotus florida (P-17), Pleurotus ostreatus (P- 19) and two exotic strains Pleurotus (florida) ostreatus (WC536), Pleurotus ostreatus (WC-522). Spawn running and mushroom fruitification were allowed to develop under optimum environmental condition. The mushroom yield data of compost bags with different concentration of medicinal plant products plants were calculated. The results showed that presence of Neem cake and Citrus lemon in the substrate increased the yield of Oyster mushroom strains i.e. Pleurotus florida) ostreatus (WC-536) followed by P. ostreatus (WC-522) strain. Neem cake and Citrus lemon were more promising in improving yield of mushroom. These results led to the conclusion that addition of specific medicinal plants concentration to compost increases the yield of Oyster mushroom by reducing the incidence of microbes and is more preferable than chemicals due to their lethal effects during human consumption of mushroom. (author)

  5. Screening of some plants used in the Brazilian folk medicine for the treatment of infectious diseases

    OpenAIRE

    Holetz Fabíola Barbiéri; Pessini Greisiele Lorena; Sanches Neviton Rogério; Cortez Diógenes Aparício Garcia; Nakamura Celso Vataru; Dias Filho Benedito Prado

    2002-01-01

    Extracts of 13 Brazilian medicinal plants were screened for their antimicrobial activity against bacteria and yeasts. Of these, 10 plant extracts showed varied levels of antibacterial activity. Piper regnellii presented a good activity against Staphylococus aureus and Bacillus subtilis, a moderate activity on Pseudomonas aeruginosa, and a weak activity against Escherichia coli. Punica granatum showed good activity on S. aureus and was inactive against the other standard strains. Eugenia unifl...

  6. Bioactive Flavone-C-Glycosides of the African Medicinal Plant Biophytum umbraculum

    OpenAIRE

    Helle Wangensteen; Drissa Diallo; Karl Egil Malterud; Celine Nguyen; Anh Thu Pham

    2013-01-01

    Three flavone-C-glycosides—cassiaoccidentalin A (1), isovitexin (2) and isoorientin (3)—were isolated from the ethyl acetate (EtOAc) soluble fraction of the methanol crude extract of the African medicinal plant Biophytum umbraculum, This is the first report of these compounds in this plant. All compounds were identified by spectroscopic analysis and comparison with published data. Isoorientin (3) and the EtOAc extract showed the greatest antioxidant activity in the DPPH assay as well as the s...

  7. Climatic Suitability of Growing Summer Squash (Cucurbita pepo L.) as a Medicinal Plant in Iran

    OpenAIRE

    Bannayan, Mohammad; Amin ALIZADEH; Ehsan Eyshi REZAEI

    2011-01-01

    Diversification of production by including a broader range of plant species, can significantly contribute to improve health and nutrition, livelihoods, household food security and ecological sustainability. Exploring the climate impact on any given crop is one of the first priorities to find new suitable areas for production and management of new crops. Summer squash (Cucurbita pepo L.) is an economically valuable plant with various medicinal potentials. In order to investigate summer squash ...

  8. Screening of siddha medicinal plants for its in-vitro acetylcholinesterase and butyrylcholinesterase inhibitory activity

    OpenAIRE

    Kadiyala, Madhuri; Ponnusankar, Sivasankaran; Elango, Kannan

    2014-01-01

    Background: The plants selected for the study were traditionally used in siddha system of medicine in neurological disorders. Aim: The aim of the following study isto screen the plant species for both acetylcholinesterase (AchE) and butyrylcholinesterase (BuchE) inhibition by in-vitro Ellman's method and a thin layer chromatography bioautographic assay for newer drug candidates for the treatment of Alzheimer's disease. Materials and Methods: Ellman's colorimetric method was performed in a 96 ...

  9. Effect of Four Medicinal Plants on Amyloid-? Induced Neurotoxicity in SH-SY5Y Cells

    OpenAIRE

    Adewusi, Emanuel A; Fouche, Gerda; Steenkamp, Vanessa

    2013-01-01

    Amyloid-beta peptide (A?) is implicated in the pathogenesis of Alzheimer's disease (AD), a neurodegenerative disorder. This study was designed to determine the effect of four medicinal plants used to treat neurodegenerative diseases on A?-induced cell death. Cytotoxicity of the ethanol extracts of the plants was determined against SH-SY5Y (human neuroblastoma) cells which were untreated, as well as toxically induced with A?, using the MTT and neutral red uptake assays. Cell viability was redu...

  10. Heavy Metals Content of Some Medicinal Plants from Kwazulu-Natal, South Africa

    OpenAIRE

    A. Sipamla; Modise, J.; E. Muleya; F. Mtunzi; E. Dikio

    2012-01-01

    Trace metals in eight different plants commonly available in South Africa, Kwazulu-Natal Province namely Gunnera perpensa, Pentanisia prunelloides, Carissa bispinosa, Ledebouria revoluta, Pomaria sandersonii, Eucomis autumnalis, Alepidea amatymbica, Artemisia afra and Berkheya setifera have been quantitatively analyzed using Atomic Absorption spectrophotometer. Medicinal plants were disinfected with 0.1% HgCl2 and digested with 95% H2SO4 and 35% H2O2. Six heavy metals (Fe, Cu, Mn, Pb, ...

  11. Utilization of Medicinal Plants by Waluguru People in East Uluguru Mountains in Tanzania

    OpenAIRE

    Mahonge, C.P.I.; Nsenga, J.V.; Mtengeti, E.J.; Mattee, A.Z.

    2006-01-01

    A study was done to assess utilization of medicinal plants in Nyachilo village situated in eastern Uluguru Mountains, Tanzania. Semi-structured questionnaires were administered and informal discussions conducted to traditional healers and midwives. The respondents were selected from Changa, Mselelo, Tanana, Mitamba, Kimeza, Mandani and Kibundi subvillages. Within the subvillages random sampling was used to determine the number of respondents to be interviewed. The study found that plant medic...

  12. Antimicrobial Activity of Some Medicinal Plants Used by Herbalists in Eastern Province, Kenya

    OpenAIRE

    Kareru, P G; Gachanja, A N; Keriko, J M; G. M. Kenji

    2007-01-01

    The aqueous extracts from medicinal plants commonly used by herbalists in Mbeere, and Embu districts of Eastern province, Kenya, were tested for their inhibitory activity against three selected strains of bacteria. All the selected plant extracts (infusions: 1.0g sample in 100 ml water) investigated showed activity against Escherichia coli with inhibition zone diameters ranging from 5.8 – 18.0 mm. Terminalia brownii gave the largest inhibition zones against E. coli and Staphylococcus aureus. ...

  13. Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of Amaryllidaceae

    DEFF Research Database (Denmark)

    Rønsted, Nina; Symonds, Matthew RE; Birkholm, Trine; Christensen, Søren Brøgger; Meerow, Alan W; Molander, Marianne; Mølgaard, Per; Petersen, Gitte; Rasmussen, Nina; Van Staden, Johannes; Stafford, Gary Ivan; Jäger, Anna

    2012-01-01

    Background: During evolution, plants and other organisms have developed a diversity of chemical defences, leading to the evolution of various groups of specialized metabolites selected for their endogenous biological function. A correlation between phylogeny and biosynthetic pathways could offer a predictive approach enabling more efficient selection of plants for the development of traditional medicine and lead discovery. However, this relationship has rarely been rigorously tested and the pote...

  14. Antibacterial Activities of Aqueous and Alcoholic Extracts of 34 Indian Medicinal Plants against some Staphylococcus species

    OpenAIRE

    PAREKH, Jigna; CHANDA, Sumitra V.

    2008-01-01

    Thirty-four Indian medicinal plants belonging to 28 different families were screened for potential antibacterial activity against 3 Staphylococcus species, namely Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus subflava. Antibacterial activity of aqueous and alcoholic extracts was performed by agar disc diffusion method and agar well diffusion method. The alcoholic extracts were more active than aqueous extracts for all the plants studied. The most susceptible bacterium ...

  15. The role of silicon in physiology of the medicinal plant (Lonicera japonica L.) under salt stress

    OpenAIRE

    Zhao Gengmao; Li Shihui; Sun Xing; Wang Yizhou; Chang Zipan

    2015-01-01

    Silicon(Si) is the only element which can enhance the resistance to multiple stresses. However, the role of silicon in medicinal plants under salt stress is not yet understood. This experiment was conducted to study the effects of silicon addition on the growth, osmotic adjustments, photosynthetic characteristics, chloroplast ultrastructure and Chlorogenic acid (CGA) production of Honeysuckle plant (Lonicera japonica L.) under salt-stressed conditions. Salinity exerted an adverse effect on th...

  16. Traditional medicinal plant use in Northern Peru: tracking two thousand years of healing culture

    OpenAIRE

    Sharon Douglas; Bussmann Rainer W

    2006-01-01

    Abstract This paper examines the traditional use of medicinal plants in Northern Peru, with special focus on the Departments of Piura, Lambayeque, La Libertad, Cajamarca, and San Martin. Northern Peru represents the center of the old Central Andean "Health Axis," stretching from Ecuador to Bolivia. The roots of traditional healing practices in this region go at least as far back as the Moche period (AC 100–800). Although about 50% of the plants in use reported in the colonial period have disa...

  17. Evaluation of foliar fungal endophyte diversity and colonization of medicinal plant Luehea divaricata (Martius et Zuccarini)

    OpenAIRE

    Juliana Bernardi-Wenzel; Adriana García; Celso J R Filho; Prioli, Alberto J.; Pamphile, João A

    2010-01-01

    Endophyte microorganisms are organisms that live inside plants without causing any apparent damage to their hosts. Since all plants exhibit endophyte microorganisms, it is believed that mutual association is of great importance in nature. Luehea divaricata (Martius & Zuccarini), known popularly in Brazil as agoita-cavalo, is a big-sized tree with a wide distribution in the country that possesses medicinal qualities for: dysentery, leucorrhea, rheumatism, blennorrhoea, tumors, bronchitis, and ...

  18. Determination of Antibacterial and Antioxidant Potential of Some Medicinal Plants from Saurashtra Region, India

    OpenAIRE

    Kaneria M; Baravalia Y; Vaghasiya Y; Chanda S.

    2009-01-01

    Many plants used in Saurashtra folk medicine have been reported to exhibit high antibacterial and antioxidant activities. In the present study, some parts of five plants, Guazuma ulmifolia L., Manilkara zapota L., Melia azedarach L., Syzygium cumini L. and Wrightia tomentosa R.& S., were evaluated for their antibacterial activity, total phenol content, flavonoid content, 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity and phytochemical analysis, using successive extraction ...

  19. Antimicrobial, Antioxidant and Cytotoxic Activities and Phytochemical Screening of Some Yemeni Medicinal Plants

    OpenAIRE

    Ulrike Lindequist; Alaghbari, Sama A. Z.; Althawab, Faisal M. N.; Sidgi Hasson; Salah A. A. Abdo; Mothana, Ramzi A. A.

    2010-01-01

    The traditional medicine still plays an important role in the primary health care in Yemen. The current study represents the investigation of 16 selected plants, which were collected from different localities of Yemen. The plants were dried and extracted with two different solvents (methanol and hot water) to yield 34 crude extracts. The obtained extracts were tested for their antimicrobial activity against three Gram-positive bacteria, two Gram-negative bacteria, one yeast species and three ...

  20. In vitro propagation of the medicinal plant Ziziphora tenuior L. and evaluation of its antioxidant activity

    OpenAIRE

    Dakah, Abdulkarim; Zaid, Salim; Suleiman, Mohamad; Abbas, Sami; Wink, Michael

    2014-01-01

    Ziziphora tenuior L. (Lamiaceae) is an aromatic herb used for its medicinal values against fungi, bacteria. Micropropagation can be used for large-scale multiplication of essential oil producing plants thus avoiding an overexploitation of natural resources. This work aims to develop a reliable protocol for the in vitro propagation of Z. tenuior, and to compare the antioxidant activity between in vitro propagated and wild plants.