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Teleost gut associated lymphoid tissue (GALT) consists of leucocyte populations located both intraepithelially and in the lamina propria with no structural organization. The present study aims to assess different protocols for the isolation of GALT cells from an important fish species in the Mediterranean aquaculture, the gilthead seabream. Mechanical, chemical and enzymatic treatments were assayed. Nylon wool columns and continuous density gradients were used for further separation of cell subpopulations. Light microscopy and flow cytometry showed that the highest density band (HD) consisted of a homogeneous lymphocytic population, whereas the intermediate density band (ID) corresponded to epithelial and secretory cells and some lymphocytes. Respiratory burst activity of total cell suspen...

British Library Electronic Table of Contents (United Kingdom)

We have colocalized elastin and fibrillin-1 with perlecan in extracellular matrix of tensional and weight-bearing connective tissues. Elastin and fibrillin-1 were identified as prominent components of paraspinal blood vessels, and posterior longitudinal ligament in the human fetal spine and outer annulus fibrosus of the fetal intervertebral disc. We also colocalized perlecan with a synovial elastic basal lamina, where the attached synovial cells were observed to produce perlecan. Elastin, fibrillin-1 and perlecan were co-localized in the intima and media of small blood vessels in the synovium and in human fetal paraspinal blood vessels. Elastic fibers were observed at the insertion point of the anterior cruciate ligament to bone in the ovine stifle joint where they colocalized with perleca...

Energy Technology Data Exchange (ETDEWEB)

The nuclear lamina proteins, prelamin A, lamin B, and a 70-kD lamina-associated protein, are posttranslationally modified by a metabolite derived from mevalonate. This modification can be inhibited by treatment with (3-R,S)-3-fluoromevalonate, demonstrating that it is isoprenoid in nature. We have examined the association between isoprenoid metabolism and processing of the lamin A precursor in human and hamster cells. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevinolin (lovastatin) specifically depletes endogenous isoprenoid pools and inhibits the conversion of prelamin A to lamin A. Prelamin A processing is also blocked by mevalonate starvation of Mev-1, a CHO cell line auxotrophic for mevalonate. Moreover, inhibition of prelamin A processing by mevinolin treatment is rapidly reversed by the addition of exogenous mevalonate. Processing of prelamin A is, therefore, dependent on ...

Science.gov (United States)

reaching their ultimate compressive strength. Thus, when applying a lamina stress analysis in conjunction with a failure model, one must ...

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To illustrate frequently encountered anatomic variations on PNS computed tomography(CT) and to assess their clinical significance. CT findings of 1523 patients, who underwent PNS CT with no history of sinus surgery, were reviewed, and prevalence of each anatomic variation and its relationship with mucociliary clearance pathway was evaluated. Two categories of anatomic variations were encountered. The first group included variations of the turbinates, such as concha bullosa(28.6%), paradoxical middle turbinate(31.5%), of the uncinate process, such as medially bent or folded(36.3%), laterally bent(3.7%) or uncinate bulla(0.5%), of the ethmoidal sinus, such as Haller's cell(28.2%), large agger nasi cell(9.6%) or large ethmoidal bulla(23.5%) and nasal septal deviation(24.1%), which might cause obstruction of mucociliary clearance pathway and thus give rise to secondary obstructive sinusitis. The second group included Onodi ...

Energy Technology Data Exchange (ETDEWEB)

Patients with acquired immunodeficiency syndrome (AIDS) are subject to a spectrum of central nervous system (CNS) disorders. Recent evidence implicates the human T-cell lymphotropic virus type III (HTLV-III) in the pathogenesis of some of these illnesses, although the cells infected by the virus have yet to be identified. Using in situ hybridization, the authors examined brain tissue from two patients with AIDS encephalopathy for the presence of HTLV-III RNA. In both cases, viral RNA was detected and concentrated in, though not limited to, the white matter. The CNS cells most frequently infected included macrophages, pleomorphic microglia, and multinucleated giant cells. Less frequently, cells morphologically consistent with astrocytes, oligodendroglia, and rarely neurons were also infected. The findings strengthen the association of HTLV-III with the ...

UK PubMed Central (United Kingdom)

If we are to stand any chance of understanding the circuitry of the superficial dorsal horn, it is imperative that we can identify which classes of interneuron are excitatory and which are inhibitory....Full Text Available

KoreaScience (Korea)

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Science.gov (United States)

Bacterial attachment-effacement (att-eff) is emerging as an important virulence characteristic common to both enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC). The contribution of the plasmid-encoded EPEC adherence factor to the production of mucosal lesions and diarrhea was investigated in gnotobiotic piglets. Bacterial att-aff in the intestinal mucosa of piglets infected with plasmid-cured EPEC strain E2348/69 (O127) was indistinguishable from that in piglets infected with the parent strain, but the distribution of lesions was different; it occurred in the small intestines of 6 of 7 piglets infected with the parent strain compared with only 2 of 11 (P = 0.006) infected with the plasmid-cured strain. Plasmid-encoded factors in EPEC and EHEC strains did not appear to contribute to bacterial competition with normal gut microflora. Of 13 strains belonging to five EPEC serogroups, O55, O142, O26, O119, and O111, 3 fulfilled the criteria for EHEC (2 O26 and 1 ...

British Library Electronic Table of Contents (United Kingdom)

An effective rehabilitation strategy is proposed to enhance the strength and stiffness of the beam-column joint in this study. An analytical model is proposed to predict the column shear of the joints strengthened with carbon fiber reinforced polymer (CFRP). Three full scale interior beam-column joints, including two specimens strengthened with CFRP and one prototype specimen, are tested in this study. The specimens are designed to represent the pre-seismic code design construction in which there is no transverse reinforcement. A new optical non-contact technique, digital image correlation (DIC), which can measure the full strain field of specimen, is used to measure and observe the full strain field of the joint. The experimental results show that the beam-column joints strengthened with ...

Science.gov (United States)

Chapter 10 of the manual that describes on-the-ground operations that strengthen the likelihood that our forests will be healthier, more diverse, and ... ...

International Nuclear Information System (INIS)

Control of thermal expansion is often necessary in the design and selection of electronic packages. In some instances, it is desirable to have a coefficient of thermal expansion intermediate between values readily attainable with single or two phase materials. The addition of a third phase in the form of fillers, whiskers, or fibers can be used to attain intermediate expansions. To help design the thermal expansion of multiphase materials for specific applications, a closed form model has been developed that accurately predicts the effective elastic properties of isotropic filled materials and transversely isotropic lamina. Properties of filled matrix materials are used as inputs to the lamina model to obtain the composite elastic properties as a function of the volume fraction of each phase. Hybrid composites with two or more fiber types are easily handled with this model. This paper reports that results for glass, quartz, and Kevlar fibers ...

British Library Electronic Table of Contents (United Kingdom)

Regularities of deformation-induced dissolution of a surface layer of iron oxides in matrixes of iron-based alloys with bcc and fcc lattices have been studied by the methods of M?ssbauer spectroscopy, transmission electron microscopy, and X-ray diffraction. A method of producing iron alloys strengthened by dispersed oxide nanoparticles and alloyed with elements possessing a high affinity to oxygen (titanium and yttrium) has been proposed, which implies a dynamic dissolution of a surface layer of iron oxides upon strong cold deformation and a precipitation of secondary yttrium and titanium nanooxides upon a subsequent high-temperature sintering of mechanically alloyed powders. There has been demonstrated a possibility of oxide strengthening of pure iron upon its interaction with air without...

Science.gov (United States)

Spike-timing-dependent plasticity (STDP), a form of Hebbian plasticity, is inherently stabilizing. Whether and how GABAergic inhibition influences STDP is not well understood. Using a model neuron driven by converging inputs modifiable by STDP, we determined that a sufficient level of inhibition was critical to ensure that temporal coherence (correlation among presynaptic spike times) of synaptic inputs, rather than initial strength or number of inputs within a pathway, controlled postsynaptic spike timing. Inhibition exerted this effect by preferentially reducing synaptic efficacy, the ability of inputs to evoke postsynaptic action potentials, of the less coherent inputs. In visual cortical slices, inhibition potently reduced synaptic efficacy at ages during but not before the critical period of ocular dominance (OD) plasticity. Whole-cell recordings revealed that the amplitude of unitary IPSCs from parvalbumin positive (Pv+) interneurons to pyramidal neurons ...

UK PubMed Central (United Kingdom)

Over the past 10 years, the Peruvian National Tuberculosis (TB) Program, the National Reference Laboratory (NRL), Socios en Salud, and US partners have worked to strengthen the national TB laboratory...Full Text Available

UK PubMed Central (United Kingdom)

A 33-year-old man sustained an acute Achilles tendon rupture which was surgically repaired. Early nonweight-bearing range of motion and strengthening of the ankle and the repaired muscle unit was allowed...Full Text Available

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AUSTRALIA-KOREA FOUNDATION ...Appendix 1: Order-in-Council establishing the Australia-Korea Foundation ...has been a successful period for the Australia-Korea Foundation in working towards strengthening and broadening the

UK PubMed Central (United Kingdom)

BackgroundChina has had no effective and systematic information system to provide guidance for strengthening PHC (Primary Health Care) or account to citizens on progress. We report...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Methods of X-ray diffraction and transmission electron microscopy were used to study the microstructure of dispersion-strengthened Cu-Al2O3 nanocomposites obtained by the method of simultaneous deposition of Cu and Al2O3 from the vapor phase. The effect of the size of particles of the oxide (Al2O3) and of their content on the electrical resistance of the composite has been considered. The results obtained make it possible to suppose that the main structural factor that determines the electrical resistance of the composite are nanodispersed particles of Al2O3 with a size of less than 20 nm.

International Nuclear Information System (INIS)

In-reactor testing of bolt-loaded compact tension specimens was performed in 360 C water. New data confirms previous results that high irradiation levels reduce SCC resistance in Alloy X-750. Low boron heats show improved IASCC (irradiation-assisted stress corrosion cracking). Alloy 625 is resistant to IASCC. Microstructural, microchemical, and deformation studies were carried out. Irradiation of X-750 caused significant strengthening and ductility loss associated with formation of cavities and dislocation loops. High irradiation did not cause segregation in X-750. Irradiation of 625 resulted in formation of small dislocation loops and a fine body-centered-orthorhombic phase. The strengthening due to loops and precipitates was apparently offset in 625 by partial dissolution of #gamma# precipitates. Transmutation of boron to helium at grain boundaries, coupled with matrix strengthening, is believed to be responsible for ...

International Nuclear Information System (INIS)

The interrelationship between the testing temperature and HfC strength increment of an arc-melted W-3.6Re-0.4HfC was determined from 1950 K to 2980 K in a vacuum of better than 1.3x10"-"5 Pa (10"-"7 torr). The present research was focused on the characteristic temperature at which the rapid coarsening of HfC particles occurred and the effect of the second-phase particle size on the high temperature strength properties of this material. It was found that the HfC particle strengthening was effective in a W-Re matrix up to a characteristic temperature of 2450 K in the short-term tensile test. Carbon was found to be the rate-limiting solute in the HfC particle growth. The strength of HfC strengthened alloy at temperature above 0.5 T_m is proportional to the square root of particle volume fraction. The yield strengths of W-3.6Re-0.26HfC calculated based on the particle statistical distribution had good agreement with the experimental values from ...

J-STORE (Japan)

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British Library Electronic Table of Contents (United Kingdom)

The International Index of Erectile Function is a well-worded and psychometrically valid self-report questionnaire widely used as the standard for the evaluation of male sexual function. However, some conceptual and statistical problems arise when using the measure with men who are not sexually active. These problems are illustrated using 2 empirical examples, and the authors provide recommended solutions to further strengthen the efficacy and validity of this measure.

International Nuclear Information System (INIS)

In-reactor testing of bolt-loaded compact tension specimens was performed in 360 C water to determine the irradiation-assisted stress corrosion cracking (IASCC) behavior of HTH Alloy X-750 and direct-aged Alloy 625. New data confirm previous results showing that high irradiation levels reduce SCC resistance in Alloy X-750. Heat-to-heat variability correlates with boron content, with low boron heats showing improved IASCC properties. Alloy 625 is resistant to IASCC, as no cracking was observed in any Alloy 625 specimens. Microstructural, microchemical and deformation studies were performed to characterize the mechanisms responsible for IASCC in Alloy X-750 and the lack of an effect in Alloy 625. The mechanisms under investigation are: boron transmutation effects, radiation-induced changes in microstructure and deformation characteristics, and radiation-induced segregation. Irradiation of Alloy X-750 caused significant strengthening and ductility loss that was ...

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Government should model good practice in social inclusion and diversity.Apply a social inclusion test ...Government should model good practice in social inclusion and diversity.Apply a social inclusion test ...Government should model good practice in social inclusion and diversity.Apply a social inclusion test

Energy Technology Data Exchange (ETDEWEB)

The purpose of the invention is to improve adaptability of a compression shield to irregularities of a face. This goal is achieved in that a compressible shield is made in the form of a lattice of elastic transverse plates with grooves, elastic vertical elements installed in the grooves, and an elastic plate which is concave toward the face. The plate is located vertically in the middle of the shield. The compressible shield is attached by hinges to a deflector. Telescopic cross pieces are attached by hinges to the covering section of reinforcement, offering the possibility of longitudinal movement at the point of attachment.

British Library Electronic Table of Contents (United Kingdom)

Abstract The term -stem cell- most commonly refers to embryonic stem cells, particularly in the lay media; however, it also describes other cell types. A stem cell represents a cell of multi-lineage potential with the ability for self-renewal. It is now clear that the plasticity and immortality of a given stem cell will depend on what type of stem cell it is, whether an embryonic stem cell, a fetal-placental stem cell or an adult stem cell. Stem cells offer great promise as cell-based therapies for the future. With evolving technology, much of the socio-political debate regarding stem cells can now be avoided.

DEFF Research Database (Denmark)

Udgivelsesdato: 2002-Mar

Science.gov (United States)

PMID:21290990

International Nuclear Information System (INIS)

Solid solution-strengthened nickel base alloys have been used for nuclear stream generator tubing in pressurized water reactors since the beginnings of commercial nuclear power. The purpose of this paper is to recap and update the authors understanding of the relationship between processing, resulting structure, and properties for Alloy 600 and to discuss the requirements for optimized performance in both primary and secondary environments. Potential replacement materials and their performance will be discussed. Also discussed is the role and importance of system chemistry, bulk and local, and control and its relationship to performance. A discussion of potential mechanisms of environmentally assisted failure is also discussed.

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...named Chair at Epworth Hospital Professor Nilmini Wickramasinghe has been named Chair, Health Information Management , at Epworth HealthCare. Related links School of Business ...the College of Business at RMIT University has been named Epworth Chair, Health Information Management , by Epworth HealthCare. Professor Wickramasinghe has more than ... Professor Wickramasinghersquo;s appointment as Epworth Chair, Health Information Management , will help to further strengthen this clinical academic alliance, with RMIT now ...

International Nuclear Information System (INIS)

The International Atomic Energy Agency is undertaking a program for strengthening its safeguards on the recognition that safeguards must give assurance not only of the non-diversion of declared material or that declared facilities are not being misused, but also of the absence of any undeclared nuclear activities in States which have signed comprehensive safeguards agreements with the Agency. The IAEA has determined that the detection of undeclared nuclear activities and the creation of confidence in the continuing peaceful use of declared material and facilities is largely dependent on more information being made available to the Agency and on the capability of the Agency to make more effective use of this additional information, as well as existing information.

British Library Electronic Table of Contents (United Kingdom)

A scant body of literature addresses competencies needed for successful job development. This study aimed to identify competencies needed for this role. In this analysis, we observed employment specialists identified as successful in helping consumers obtain employment perform job development duties. We supplemented observations with interviews. Employment specialists possessed competencies in six domains: time management, advocacy, building partnerships with consumers, working as part of a team, face-to-face communication, and networking. The conceptual framework derived from this study can inform supported employment supervisors and researchers about the competencies that can strengthen supported employment teams.

KoreaScience (Korea)

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KoreaScience (Korea)

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CERN Document Server

Applied and fundamental aspects of plant cell, tissue, and organ culture

Energy Technology Data Exchange (ETDEWEB)

To evaluate injury patterns of facet joints and associated soft tissue injuries in patients with acute traumatic cervical facet joint injuries. From among patients with cervical spine trauma, 27 with facet joint injuries, as seen on CT and MRI, were chosen for this study. CT scans were analyzed with regard to the location of facet joint injury, the presence or absence of facet dislocation or fracture, and other associated fractures. MR images were analyzed with regard to ligament injury, intervertebral disc injury, intervertebral disc herniation, and spinal cord injury. The most common location of facet joint injury was C6-7 level(n=10), followed by C5-6(n=8). Among these 27 patients with facet joint injuries, 12(44%) had bilateral injuries and 15(56%) unilateral injuries. Facet fractures were present in 17 cases(63%) and the fracture of inferior facet was more frequent than superior. Patterns of fracture were vertical, transverse, or comminuted, but vertical fracture was the most ...

Science.gov (United States)

... Solar Cell Radiation Respinnse Near the Interface o~f fliffprerv- ... 5 4. CALCUTl-ATED SOLAR CELL RLSPONSE FOR VARIOUS BASE MATERIALS ...

Energy Technology Data Exchange (ETDEWEB)

Experiments were designed to elucidate whether or not the irradiated bone marrow cells receive any stimulation for the self-replication and differentiation from normal 'stromal' cell colonies in the bone marrow cell culture in vitro. When irradiated or unirradiated bone marrow cells were overlaid on the normal adherent cell colonies, the proliferation of haemopoietic stem cells was supported, the degree of the stimulation depending on the starting cellular concentration. There was, however, no significant changes in the concentration of either CFUs or CFUc regardless of the dose of irradiation on the bone marrow cells overlaid. This was a great contrast to the dose-dependent decrease of CFUs or CFUc within the culture in which both the stem cells and stromal cells were ...

UK PubMed Central (United Kingdom)

In most adult tissues there reside pools of stem and progenitor cells inside specialized microenvironments referred to as niches. The niche protects the stem cells from inappropriate expansion...Full Text Available

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... Fuel Cell Technologies Equipment on Environmental Expert Find and compare a variety of fuel cell technologies equipment on the world's largest environmental industry portal. View ...

UK PubMed Central (United Kingdom)

Purpose.There is a paucity of neuron replacement studies for retinal ganglion cells. Given the complex phenotype of these neurons, replacement of ganglion cells may be impossible....Full Text Available

UK PubMed Central (United Kingdom)

We report the isolation of adherent, clonogenic, fibroblast-like cells with osteogenic and adipogenic potential from the blood of four mammalian species. These cells phenotypically resemble but are...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Effects of cell concentrations on the survival and repopulation of haemopoietic stem cells after irradiation were studied in the long-term culture of mouse bone marrow cells in vitro. No difference was observed in the survival of the stem cells among cultures in which 0 - 10/sup 7/ cells were re-inoculated on the adherent cell colonies in the culture flask. Stem cells showed a significant proliferation within 1 week and the number of the stem cells exceeded the control in 3 weeks after irradiation in the cultures with less than 10/sup 6/ re-inoculated cells per flask. In contrast, there was a considerable delay in the onset of stem cell proliferation after irradiation in the culture with 10/sup 7/ cells per flask. Based on these results, a possibility that a ...

Energy Technology Data Exchange (ETDEWEB)

The report, Water Resources Management in Asia, has three objectives: To describe the situation confronting the region's borrowers, devise approaches to better deal with the present and future water related problems that affect their well-being and equip the staff to actively participate in the regional and Bank-wide efforts to strengthen the sector. The principal water resources problems and issues have been placed in four categories: Institutional, long-term management and planning, real-time management and operations, and financial. Such an arrangement provides a perspective for examining concerns across all economic sectors and allows formulation of solutions that will constitute a truly comprehensive, balanced approach to the critical situation encountered in managing these resources. A summary of past Bank activities has confirmed that an historic approach is not adequate to address the pressing problems of today and the future.

Science.gov (United States)

The Education for All-Fast Track Initiative (FTI) grew out of the "New Focus on Education for All" communique of the G-8 when Canada hosted the summit in 2002 at Kananaskis. As Canada prepares again to host the G-8, and Korea assumes leadership of the newly-empowered G-20, it is a valuable moment to revisit and re-think the current global education architecture. By adopting some of the recommendations from the recent independent evaluation of the FTI and borrowing some lessons from global partnerships in other sectors, the FTI could set a new course toward the achievement of universal basic education. The FTI should broaden and strengthen the role of diverse stakeholders from developing countries and civil society in its governance structure in order to fully harness the energies of these stakeholders in resource mobilization and effective implementation. (Contains 9 endnotes.)

Energy Technology Data Exchange (ETDEWEB)

Development of a comprehensive and effective global clean technology cooperation framework will require years of experimenting and evaluation with new instruments and institutional arrangements before it is clear what works on which scale and in which region or country. In presenting concrete examples, this paper aims to set the first step in that process by highlighting successful models and innovative approaches that can inform efforts to ramp up clean energy technology cooperation. This paper reviews current mechanisms and international frameworks for global cooperation on clean energy technologies, both within and outside of the UNFCCC, and provides selected concrete options for scaling up global cooperation on clean energy technology RD&D, enabling environment, and financing.

International Nuclear Information System (INIS)

The changed political situation and recognition of the acute destruction of the natural environment in Poland have caused a series of actions aimed at preventing further deterioration of Polish environment. One of the most important events which took place in the last few years was the enactment by the Polish Parliament in May 1991 of the Act on the National Ecological Policy. The basic assumption of the new environmental policy is a declaration that sustainable development will in future direct economic development in Poland. The aim of the presented paper is to introduce existing policy of air protection and instruments which have been implemented to protect the air. Special attention is paid to legislation instruments, introduction and enforcement of proper economic mechanisms strengthening air protection and foreign policy aiming at increasing foreign assistance for this objective. Pollutants involved include sulfur dioxide, nitrogen oxides, carbon dioxide and ...

Energy Technology Data Exchange (ETDEWEB)

Mechanical alloying is an important pre-requisite for the manufacturing of heat resistant oxide-dispersion-strengthened superalloys. Though the microstructure of these materials after hot extrusion and recrystallization treatment is well documented, little is known about the microstructural evolution during ball-milling. A method was tested to prepare electron transparent foils and extraction replica from powder particles for TEM investigations. The microstructure was found to consist of a Ni-Cr-Al solid solution in which submicron particles of refractory metals were embedded. The extremely fine grainize of about 50 nm is the consequence of severe plastic deformation. Yttria particles could not be detected in the powder after ball milling, but after a heat treatment at 1000 C the well-known fine dispersion of oxide particles was evident. (orig.)

British Library Electronic Table of Contents (United Kingdom)

Purpose Two main pathways of phytoremediation of heavy metal-contaminated soils are phytostabilization and phytoextraction. Some soil amendments can strengthen phytostabilization or phytoextraction through either reducing heavy metal bioavailability in soil or increasing the heavy metal accumulation capacity of the hyperaccumulator (enhancing heavy metal concentration or shoot biomass of the hyperaccumulator). Urea and chicken manure are often used as fertilizers. This research will explore their effects on a newly found hyperaccumulator, Rorippa globosa (Turcz.) Thell., phytoremediating cadmium (Cd). Materials and methods Pot culture experiment was conducted to study the accumulation characteristics of R. globosa at different Cd contamination concentrations under one fertilizer level (1?g...

British Library Electronic Table of Contents (United Kingdom)

A fully lamellar ferrite/cementite nanostructure was designed in a low C steel by using a specific thermal treatment. The strengthening of such microstructure has been investigated as a function of prestrain by rolling up to a deformation of 300%. As in usual pearlitic structure, its work-hardening shows no saturation and its elongation to fracture remains rather constant instead of decreasing drastically as conventional steels. The hardening by a similitude effect is thus not the privilege of pearlitic steels. Nevertheless, its lower initial work-hardening rate at low strain compared to an equivalent pearlitic steel and a lower hardening potential at high strain let us suspect major differences in the nature and the behaviour of ferrite channels in relation to the morphogenesis of the mic...

British Library Electronic Table of Contents (United Kingdom)

The number of spent fuel storage facilities in the world continues to increase because of "Wait and See" policies and delay of a permanent disposal plan. The temporary spent fuel storage concept is changing to a pre-disposal storage concept. Strengthened safety concepts are required for expanded spent fuel storage facilities and sites. The Korea Hydro and Nuclear Power Company is planning to construct a reinforced concrete MACSTOR-400 facility at Wolsung. In concrete dry spent fuel storage structures, cracks can occur due to radiant heat and environmental chloride. The likelihood of cracking increases over time. Research on changes in shielding performance from one collinear crack in the surface of a concrete facility has been carried out. However there is no research about public radiolog...

British Library Electronic Table of Contents (United Kingdom)

The article maps the risk management failures within Anglo Irish Bank, showing that, when banks are systemic in nature, poor internal corporate governance within a Minsky credit cycle can lead to destabilising macroeconomic conditions, which may prolong the effects of a credit-induced downturn. The article highlights a failure of management at Anglo Irish Bank to establish and measure firm-level risks and develop appropriate internal controls to support a culture of prudent credit management. We propose the adoption of a novel supervisory architecture based on the meta-risk regulatory philosophy, which is designed to strengthen risk management practices at banks.

Science.gov (United States)

Applying an underfeed system, the underfeed circulating spouted bed was designed as a desulfurization reactor. The main objective of the technology is to improve the mixing effect and distribution uniformity of solid particles, and therefore to advance the desulfurization efficiency and calcium utility. In this article, a series of experimental studies were conducted to investigate the fluidization behavior of the solid-gas two-phase flow in the riser. The results show that the technology can distinctly improve the distribution of gas velocity and particle flux on sections compared with the facefeed style. Analysis of pressure fluctuation signals indicates that the operation parameters have significant influence on the flow field in the reaction bed. The existence of injecting flow near the underfeed nozzle has an evident effect on strengthening the particle mixing.

UK PubMed Central (United Kingdom)

Terminal differentiation of many vascular cells involves cell wall changes. Cells first elongate their primary wall, then lay down a lignified secondary wall, which is often followed by digestion of...Full Text Available

UK PubMed Central (United Kingdom)

Totipotent stem cells have the potential to differentiate into every cell type. Renewal of totipotent stem cells in the germline and cellular differentiation during early embryogenesis rely upon posttranscriptional...Full Text Available

UK PubMed Central (United Kingdom)

AIM: To isolate and identify the biological characteristics of human colon cancer stem cells (SW1116 cells) and further study their proteome.METHODS: SW1116 cells were isolated and cultured with...Full Text Available

Science.gov (United States)

Not Available

UK PubMed Central (United Kingdom)

BackgroundStem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target cancer stem cells...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundAs the resident stem cells of skeletal muscle, satellite cells are activated by extracellular cues associated with local damage. Once activated, satellite cells will re-enter...Full Text Available

UK PubMed Central (United Kingdom)

We describe the lethal, recessive accelerated-cell-death11 Arabidopsis mutant (acd11). Cell death in acd11 exhibits characteristics of animal apoptosis...Full Text Available

UK PubMed Central (United Kingdom)

Background:Stem cells can differentiate into multiple cell types, and therefore can be used for cellular therapies, including tissue repair. However, the participation of stem cells...Full Text Available

Science.gov (United States)

Not Available

UK PubMed Central (United Kingdom)

Hematopoietic stem cells replenish all the cells of the blood throughout the lifetime of an animal. Although thousands of stem cells reside in the bone marrow, only a few contribute to blood production...Full Text Available

KoreaScience (Korea)

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UK PubMed Central (United Kingdom)

In the growing chloronema cell suspension cultures of the moss Funaria hygrometrica Hedw., activities of several enzymes have been found to be cell-density-dependent. Cyclic nucleotide...Full Text Available

Science.gov (United States)

...false Guidelines for Human Stem Cell Research Presidential Documents ...2009 Guidelines for Human Stem Cell Research Memorandum for the Heads...scientifically worthy human stem cell research, including human...

Wastenet

...Basic Information | Fuel Cells & Vehicles | US EPA This web page provides basic information on EPA's Fuel Cells & Vehicles web site ...including the chemical composition of fuel cell technology, how it works, descriptions of the various types of fuel cells , their availability and ... background,electrochemical,hydrogen,fuel cell,fuel cell vehicle,fuel reformer,performace,improved fuel economy,increased engine efficiency,lower emissions,zero emissions,availablity,fuel cell types,diagram,Proton ...Exchange Membrane,PEM Basic Information | Fuel Cells & Vehicles | US EPA background,electrochemical,hydrogen,fuel cell,fuel cell vehicle,fuel reformer,performace,improved fuel economy,...

Science.gov (United States)

Students get a background on Stem Cell technology and learn to write an effective opinion essay.

Energy Technology Data Exchange (ETDEWEB)

Laser-assisted processing techniques for producing high-quality solar cell metallization patterns are investigated, developed, and characterized. The tasks comprising these investigations are outlined. A new batch of solar cells was processed using the laser decomposition of spun-on silver neodecanoate to metallize cells. Decomposition of silver neodecanoate was carried out at different laser powers on different cells on a given wafer to determine whether this would have any effect on cell performance. Solar cells which were written with laser powers of 5 to 8 watts, gave excellent results with cell efficiencies in the range of 14 to 16%.

Science.gov (United States)

... nent to the design and construction of metal-semiconductor solar cells, in that both the photovoltage and the efficiency of metal-semiconductor cells ...

Energy Technology Data Exchange (ETDEWEB)

In the next few decades, the probable strengthening of the greenhouse effect may bring about considerable changes in energy production and consumption, which depend on climate. It is presumed that some of the changes will occur even if the rise in greenhouse gas concentration will be reduced. Because the investments in energy production have a long-term influence, decision-makers should have an idea about the impact of the strengthening of the greenhouse effect on energy production and consumption in Finland. According to the results of this study, the effects of climate change on the total consumption and production of electricity will be limited. The structure of both electricity consumption and production will remain rather similar, the most important changes applying to hydro power. The consumption of heating electricity will decrease substantially. Because the non- climate-dependent sectors of electricity consumption (process industry and ...

DEFF Research Database (Denmark)

In order to identify cells of maternal origin in CVS cultures, tissue from 1st trimester abortions were cultivated and the cultures stained in situ for X-chromatin. Convoluted cells and maternal fibroblasts were found to be positive. By chromosome analysis of cultures from 105 diagnostic placenta biopsies, obtained by the transabdominal route, metaphases of maternal origin were found in nine cases. In eight of these cases colonies of convoluted cells were observed. We conclude that convoluted cells are of maternal origin and are a reliable marker for maternal cell contamination in CVS cultures.

International Nuclear Information System (INIS)

Understanding prostate stem cells may provide insight into the origin of prostate cancer. Primary cells have been cultured from human prostate tissue but they usually survive only 15-20 population doublings before undergoing senescence. We report here that RC-170N/h/clone 7 cells, a clonal cell line from hTERT-immortalized primary non-malignant tissue-derived human prostate epithelial cell line (RC170N/h), retain multipotent stem cell properties. The RC-170N/h/clone 7 cells expressed a human embryonic stem cell marker, Oct-4, and potential prostate epithelial stem cell markers, CD133, integrin #alpha#2#beta#1"h"i and CD44. The RC-170N/h/clone 7 cells proliferated in KGM and Dulbecco's Modified Eagle Medium with 10% fetal bovine serum and 5 #mu#g/ml insulin (DMEM + 10% FBS + Ins.) ...

British Library Electronic Table of Contents (United Kingdom)

Introduction: Haploidentical transplantation, with extensive T cell depletion to prevent GvHD, is associated with a high incidence of infection-related deaths. The key challenge is to improve immune recovery with allogeneic donor T cells without triggering GvHD. As T regulatory cells (Tregs) controlled GvHD in pre-clinical studies, the present study evaluated the impact of an infusion of donor CD4/CD25 + Tregs, followed by an inoculum of donor mature T cells (Tcons) and positively immunoselected CD34 + cells in the setting of haploidentical stem cell transplantation. Patients and methods: Twenty-eight patients were enrolled in this study (22 AML; 5 ALL; 1 NHL). All received immunoselected Tregs (CliniMACS, Miltenyi Biotec) followed by positively immunoselected CD34 + cells together with Tc...

Energy Technology Data Exchange (ETDEWEB)

The article is the second part of a review dealing with latest developments in the area of solar cell technologies and application. Physical principles, design and efficiency as well as advantages and disadvantages of GaAs- and CdS-solar cells are described. Power generation solar cell systems with voltage converters, combined solar cell/solar collector systems and thermoelectric solar systems are presented in the second part of the article.

UK PubMed Central (United Kingdom)

Cell therapy is a promising novel option for treatment of cardiovascular disease. Because the role of bone marrow-derived circulating progenitor cells (BM-CPCs) after cell therapy is less clear, we...Full Text Available

UK PubMed Central (United Kingdom)

Although human T-cell lymphotropic virus type I (HTLV-I) is the etiologic agent of adult T-cell leukemia/lymphoma (ATL), the role of viral gene expression in the progression to and maintenance of the...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Solid Oxide Fuel Cell (SOFC) is expected as a new power generation source. The development of SOFC is being conducted by CRIEPI, and so far several reports of the reults were presented. This report examines materials of SOFC. For the purpose, cells were made using some of typical materials and manufacturing processes, and cell performance tests were carried out.

UK PubMed Central (United Kingdom)

The penetration by moxifloxacin of human neutrophils (polymorphonuclear leukocytes [PMN]) and tissue-cultured epithelial cells (McCoy cells) was evaluated by a fluorometric assay. At...Full Text Available

UK PubMed Central (United Kingdom)

SUMMARYThe cytolytic activity of natural killer (NK) cells is regulated by inhibitory receptors that detect the absence of self molecules on target cells. Structural studies of...Full Text Available

Science.gov (United States)

Embryonic stem cells have the ability to develop into virtually any cell in the body, and may have the potential to treat medical conditions such as diabetes and Parkinsons disease. On August 9, 2001, President Bush announced that for the first time feder...

UK PubMed Central (United Kingdom)

BackgroundSpindle cell carcinoma (SpCC) is a rare microscopic type of cancer of the mouth and oropharynx. Although SpCC is thought to arise from squamous cell carcinoma (SCC), it...Full Text Available

Science.gov (United States)

... from Dr. Austin Smith of the Institute for Stem Cell Research, University of Edinburgh) was modified from the CGR8 ... to thank Dr. Austin Smith, the Institute for Stem Cell Research, University of Edinbu...

Science.gov (United States)

... Results of Source Emissions Testing UTC Fuel Cell Model PC25C ... Results of Source Emissions Testing: UTC Fuel Cell Model PC25C ...

UK PubMed Central (United Kingdom)

Target of rapamycin (TOR) kinases control cell growth through two functionally distinct multiprotein complexes. TOR complex 1 (TORC1) controls temporal cell growth and is sensitive to rapamycin, whereas...Full Text Available

UK PubMed Central (United Kingdom)

The cells of the endosperm of castor bean seeds (Ricinus communis) undergo programmed cell death during germination, after their oil and protein reserves have been mobilized. Nuclear...Full Text Available

UK PubMed Central (United Kingdom)

The rate and capacity for chloroform (CF) and trichloroethylene (TCE) transformation by a mixed methanotrophic culture of resting cells (no exogenous energy source) and formate-fed cells were measured....Full Text Available

UK PubMed Central (United Kingdom)

PURPOSE: To determine the frequency of ophthalmic abnormalities in patients with cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome) and T-cell lymphoma involving the skin and...Full Text Available

UK PubMed Central (United Kingdom)

The primary aim of this study was to develop a model system that uses epidermal cells (keratinocytes and accessory pigmented cells) cultured on a reconstituted basement membrane biomatrix for use in...Full Text Available

UK PubMed Central (United Kingdom)

Special red cells were found on the adaxial surface of tertiary pulvini of Mimosa pudica and experiments performed to determine the origin and function of these cells. Using anatomical...Full Text Available

UK PubMed Central (United Kingdom)

Adhesion of Spirogyra (tentatively, Spirogyra fluviatilis) cells to glass is described. The cells of an algal filament can adhere to a substrate only when they are...Full Text Available

UK PubMed Central (United Kingdom)

Understanding the interactions between herpesviruses and their host cells and also the interactions between neoplastically transformed cells and the host immune system is fundamental to understanding...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundStem cells divide to reproduce themselves and produce differentiated progeny. A fundamental problem in human biology has been the inability to measure how often stem cells...Full Text Available

UK PubMed Central (United Kingdom)

Although most self-reactive T cells are eliminated in the thymus, mechanisms to inactivate or control T cells specific for extrathymic antigens are required and exist in the periphery. By investigating...Full Text Available

UK PubMed Central (United Kingdom)

One of the major decisions that germ cells make during their development is whether to differentiate into oocytes or sperm. In mice, the germ cells’ decision to develop as male or female depends...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

It Peripheral blood progenitor enriched CD34+ cells (PBPC) are rather often used as stem cell background in cancer patients following high dose therapy. Keeping in mind that precursor dendritic cells (DCs) originate from haematopoietic progenitor cells, purified CD34+ cells might also serve as starting cells for ex-vivo production of DC. The aim of the present study is to develop a clinical grade procedure for ex-vivo production of DC derived from enriched CD34+ cells. Various concentrations of CD34+ cells were grown in gas-permeable Teflon bags with different serum-free and serum-containing media supplemented with GM-CSF, IL-4, TNF-a, SCF, Flt-3L and INF-a. Serum-free CellGroSCGM medium for 7 days followed by CellGroDC medium in 7 days gave equal results as serum-containing ...

UK PubMed Central (United Kingdom)

The first cell lineage specification in mouse embryo development is the formation of trophectoderm (TE) and inner cell mass (ICM) of the blastocyst. This article is to review and discuss the...Full Text Available

UK PubMed Central (United Kingdom)

Naturally occurring and contaminant ferromagnetic and ferrimagnetic particles have been found within or near cells, and might allow pulsed magnetic fields to create transient cell membrane opening ("pores")....Full Text Available

Science.gov (United States)

... ions. MATERIALS AND METHODS Cell Culture Culture of NT2/D1 cells was carried out as described previously (18, 19). NT2 cells were plated at a density of 2. ... ...

UK PubMed Central (United Kingdom)

1. Paired or single recordings of paraventricular and/or supraoptic oxytocin cells at the beginning of suckling in urethane-anaesthetized rats enabled us to study cell recruitment and compare the characteristics...Full Text Available

UK PubMed Central (United Kingdom)

Cells have an internal compass that enables them to move along shallow chemical gradients. As amoeboid cells migrate, signaling events such as Ras and PI3K activation occur spontaneously on pseudopodia....Full Text Available

UK PubMed Central (United Kingdom)

Species differences in lifespan have been attributed to cellular survival during various stressors, designated here as ‘cell resilience’. In primary fibroblast cultures, cell...Full Text Available

UK PubMed Central (United Kingdom)

We review the application of C. elegans as a model system to understand key aspects of stem cell biology. The only bona fide stem cells in C. elegans...Full Text Available

UK PubMed Central (United Kingdom)

SummaryFor mammalian somatic cells the importance of microtubule cytoskeleton integrity in interphase cell cycle progression is uncertain. The loss, diminishment, or stabilization...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundA fundamental requirement for the exploitation of embryonic stem (ES) cells in regenerative medicine is the ability to reproducibly derive sufficient numbers of cells of...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveThe goal of the study was to investigate the genetic and molecular basis of a novel syndrome of marked hyperglucagonemia and pancreatic α cell hyperplasia...Full Text Available

International Nuclear Information System (INIS)

It may result in acute radiation syndrome after body is exposed to ionizing radiation. The one of long-term effects of irradiation injury is leukemia. The bone marrow cells (BMC) transplantation including stem cells is the only effective therapy for acute radiation syndrome patients. Recently, with the advancement of stem cell research that the stem cells have multipotential and can convert each other, it may supply the new stem source for the irradiation injury patients. At the same time with the further research of radioprotective reagents, the hematopoietic stem cells proliferation after irradiation injury is promoted

Energy Technology Data Exchange (ETDEWEB)

As concern regarding global environmental problems such as the greenhouse effect and acid rain has increased, so too has the demand for commercially viable solar cells as a clean energy source. Interest in amorphous silicon (a-Si) solar cells has been particularly high, due to their low cost. Technological developments in the field of a-Si solar cells are discussed from the viewpoints of fabrication process, materials, and cell structures. Various applications and systems that take advantage of the a-Si solar cell are then introduced. Finally, future prospects are mentioned

Science.gov (United States)

In this contract, Laser-assisted processing techniques for producing high-quality solar cell metallization patterns are being investigated, developed, and characterized. The tasks comprising these investigations are outlined. Four new batches of solar cells were processed, in addition to several test runs on wafers, using the laser decomposition of spun-on silver neodecanoate to metallize cells. Decomposition of silver neodecanoate was carried out at different laser powers on different cells on a given wafer to determine whether this would have any effect on cell performance. A one watt laser power gave an electroplated linewidth of 50 microns , while at 8 watts the line width was 90 microns.

Energy Technology Data Exchange (ETDEWEB)

The theory for the general case of solar cells operating inside integrating cavity receivers is established. This is applied to the particular case of different configurations of silicon and GaAs cells. The results of the analysis show that a composite system of silicon and GaAs cells manufactured using relatively simple technology could reach an efficiency of 34%. The optimal configuration is that in which the GaAs cells are placed in the directly illuminated area of the receiver and the silicon cells are placed in the indirectly illuminated area of the receiver. (orig.).

International Nuclear Information System (INIS)

In 1998, in the frame of the ITER EDA phase, an European R and D Programme for the Blanket Design was implemented for developing and selecting the materials and the relevant fabrication procedures for manufacturing the shielding modules of the ITER Primary Wall. The fabrication of several Beryllium armored small scale mock-ups, reproducing representative portions of a Primary Wall panels, was also launched (Fusion Technol. (1998) 195). Further experimental activities were also programmed for investigating the thermal-mechanical behavior of these mock-ups at high heat flux and under thermal fatigue tests. In 2001, the ITER European Home Team decided to assign to ENEA a contract for the thermal fatigue testing of six mock-ups aiming at verifying the reliability of the Beryllium/Dispersion Strengthened Copper alloy/Stainless Steel and Beryllium/Precipitation hardened Copper alloy/Stainless Steel joints manufactured by solid Hot Isostatic Pressing (HIP) procedure ...

Science.gov (United States)

I review the past and present of wound ballistics research in China and look toward the future of this subject. The main points area as follows: (1) Before the 1970s, China did not conduct any experimental study on wound ballistics. (2) After the 1970s, experts in ordnance and medicine closely cooperated to conduct a series of experiments or tests on wound ballistics, such as wounding effects and the mechanism of various high-speed projectiles, the treatment of the protection from firearm wounds, high quality of ammunition design, lethality criterion, blast injuries, etc. Between 1981 and 1993, four national symposia on wound ballistics were held in China. In 1988, China sponsored the Sixth International Symposium on wound Ballistics. China has made great contributions to this subject. (3) As for the future of Chinese research on wound ballistics, I suggest strengthening the following areas: the relationship with weapons traumatology; the basic science research on ...

Energy Technology Data Exchange (ETDEWEB)

Deregulation of utilities will require providers of electric power to put the issue of competition at the top of their strategic planning agenda. The companies that will flourish in this new competitive environment are those that have strongly committed customers and potential to grow. {open_quotes}Commitment{close_quotes} is the complex psychological bond between a customer and a brand (or choice); it is critical to measure because it is the foundation of loyalty and brand equity. The Conversion Model is an established, validated strategic research tool that measures customer commitment and potential to change. It was designed to help marketers devise strategies to strengthen the commitment of current customers and to acquire new customers. The Model helps companies protect and grow their businesss by first quantifying the commitment of current customers and the potential to convert competitors` customers. Further, the Model provides managers with actionable ...

Science.gov (United States)

The iron hormone hepcidin is inhibited by matriptase-2, a liver serine-protease encoded by TMPRSS6 gene. Cleaving the BMP-coreceptor hemojuvelin, matriptase-2 impairs the BMP/SMAD signaling pathway, downregulates hepcidin and facilitates iron absorption. TMPRSS6 inactivation causes iron-deficiency-anemia refractory to iron administration both in humans and mice. Genome wide association studies have shown that the SNP rs855791, which causes the matriptase-2 V736A amino acid substitution, is associated with variations of serum iron, transferrin saturation, hemoglobin and erythrocyte traits. Here we show that in vitro matriptase-2 736(A) inhibits hepcidin more efficiently than 736(V). Moreover, in a genotyped population, after exclusion of samples with iron deficiency and inflammation, hepcidin, hepcidin/transferrin saturation and hepcidin/ferritin ratios were significantly lower and iron parameters were consistently higher in homozygotes 736(A) than in 736(V). Our results indicate that ...

International Nuclear Information System (INIS)

By using a plasma nitriding procedure at the PUPR Mirror Cusp Plasma machine, surface hardness is increased in 302/304-type stainless steel samples by exposing them to high-ion-density plasma at high vacuum. This method successfully dopes the surface of the material with strengthening nitrogen ions, without the use of chemical procedures that sacrifice the resistance to corrosion of the given material. A 500 V negative bias is placed on the sample exposed to the nitrogen plasma, where high-energy ions are therefore attracted and immersed into the metallic matrix microns into the surface of the stainless steel. This potential maintains a constant surface temperature at approximately 800 deg. C. The plasma parameters including ion density and plasma temperature were diagnosed using single Langmuir probes. The stainless steel samples were then tested using scanning electron microscopy (SEM), and Vickers micro-hardness testing to determine the increment in the surface ...

Energy Technology Data Exchange (ETDEWEB)

In this study, the bend properties of the single-crystalline molybdenum brazed by using Mo-40%Ru alloys containing boron of 1-6 mass%Ru alloy for the improvement of the joint strength was determined. (orig.) [Deutsch] Durchgefuehrt wurde die Herstellung von Verbindungen aus einkristallinem Molybdaen. Hierbei kamen Mo-40%Ru-Legierungen mit 1 bis 6 Gew.-% Bor als Lotmaterialien zum Einsatz. Festigkeit und Duktilitaet der Verbindungen wurden mittels 3-Punkt-Biegepruefung bei Raumtemperatur und unter fluessigem Stickstoff ermittelt. Die Bruchflaechen der Proben wurden mit Hilfe eines Rasterelektronenmikroskopes untersucht. Die Ergebnisse lassen sich wie folgt zusammenfassen: Der optimale Borgehalt bezueglich Festigkeit und Duktilitaet der geloeteten Verbindung liegt bei 2 Gew.-%. Die entsprechende Probe hat bei einem Biegewinkel von 100 bei Raumtemperatur nicht versagt. Auch unter fluessigem Stickstoff zeigte diese Probe eine Festigkeit in der Groessenordnung des einkristallinen ...

International Nuclear Information System (INIS)

In 2001, EFDA has assigned to ENEA a contract for the thermomechanical testing of six mock-ups of the ITER primary wall module. These small scale mock-ups, reproducing representative portions of the reference ITER primary wall panels, were fabricated during ITER EDA phase by solid hot isostatic pressing (HIPping) of an AISI 316L stainless steel back structure to a alumina dispersion strengthened (DS)-Cu alloy heat sink armored with beryllium tiles. The experimental program, carried-out at ENEA Brasimone CEF 1-2 thermal hydraulic facility, was focused on the thermal mechanical testing of these mock-ups aiming at verifying which tile geometry and manufacturing procedure assures the required reliability of the beryllium/DS-Cu alloy/SS joints at high incident heat flux (>0.8 MW/m"2) both at steady state and under thermal fatigue tests. The paper presents the progress in the experimental activity of the first test campaign and the main thermomechanical FEM analyses ...

Energy Technology Data Exchange (ETDEWEB)

A porous tooling system was selected for the processing of Graphite/PMR-15 Polyimide laminates in thickness up to 3.2 mm. (0.125 inch). This tool system must have a reasonable strength, permeability dimensional stability, and thermal conductivity to accomplish curing at 600 F and 200 psi and 200 psi autoclave temperature and pressure. A permeability measuring apparatus was constructed and permeability vs. casting water level determined to produce tools at three different permeability levels. On these tools, laminates of 5, 11, and 22 plies (.027, .060, and 0.121 inch) were produced and evaluated by ultrasonic, mechanical, and thermal tests to determine the effect of the tool permeability on the cured laminates. All tools produced acceptable laminates at 5 and 11 plies but only the highest permeability produced acceptable clear ultrasonic C-Scans. Recommendations are made for future investigations of design geometry, and strengthening techniques for porous ceramic ...

International Nuclear Information System (INIS)

For satisfaction of international growing demand for electrical energy it is impossible to ignore contribution of nuclear power. With an expected lifespan for nuclear plants estimated to 50-60 years of operation (years for decommissioning added), there is a need for a steady multi-generational stream of competent staff to ensure safe operations of nuclear plants. It is incumbent to governments to invest in education, research, and training for the three to five generations of people who will construct, operate and eventually decommission nuclear plants over the duration of their life cycle. To develop sustained nuclear programs it is necessary to carry out a lot of major problems, but three of them look like as most important: 1. Training a qualified and competent personal to ensure all nuclear activities; 2. Multilateral approach for nuclear fuel cycle, with a guaranteed framework for ensuring the supply of NPP owners with the necessary nuclear fuel; 3. ...

Energy Technology Data Exchange (ETDEWEB)

Aerospace gas turbine disks operate in an environment of relatively high stresses caused by centrifugal forces and elevated temperatures. These severe conditions necessitate the need for materials with high temperature strength and good low cycle fatigue resistance. One class of alloys used for this task is the nickel base superalloys, out of which, IN 718 is the most widely used in the aerospace industry. The properties of IN 718 are attributed to the combined effects of the chemistry, heat treatment, and microstructure. The chemistry is tailored not only for solid solution strengthening but also for precipitation hardening developed during heat treatment, which combined with a fine grained microstructure lead to excellent mechanical properties such as low cycle fatigue resistance and elevated temperature strength. The properties of a gas turbine disk are sensitive to the microstructure, in particular the grain size, which is dependent on the processing history. ...

Energy Technology Data Exchange (ETDEWEB)

This paper summarizes results of reviews on the safety, critical software performed during the licensing process for the new Wolsung units. Each of these CANDU-type nuclear power plants has two micro-computerized shutdown systems. The SDS No. 1 program is graphically programmed in such a manner that its development process does not essentially differ from the design process of the conventional analog counterpart. This approach is understandable even to a reviewer in the regulatory agency without additional training in software engineering. The confidence in the reliability of this system is strengthened by the reverse verification and increased by extensive testing such as the reliability test. Concerning SDS No. 2, the development process is significantly influenced by the {open_quotes}software cost reduction project{close_quotes} of the U.S. naval research laboratory, and is, as a whole, clear and well structured except for the modules related to the operation of ...

Energy Technology Data Exchange (ETDEWEB)

The liberalisation of the energy markets requires completely new demands to the information processing procedure of energy supply enterprises. These requirements are to be understood as chances for strengthening of the terms of competition. In the following contribution to this subject the actual status of the concept as converted by the Electricity Supply Company of Halle (Saale) including their departments of district heating, gas and electricity supply will be presented. This concept are comprising all experiences as gathered so far as well as intended further actions to be executed. (orig.) [German] Die Liberalisierung der Energiemaerkte stellt fuer Versorgungsunternehmen voellig neue Anforderungen an die Informationsverarbeitung. Diese Anforderungen sind als Chancen zur Staerkung der Wettbewerbsfaehigkeit zu verstehen. Die Verfasser erlaeutern den aktuellen Stand des in der EVH GmbH Halle (Saale) im Querverbund der Sparten Fernwaerme, Gas und Elektrizitaet ...

International Nuclear Information System (INIS)

Ti-15Mo-2.7Nb-3Al-0.2Si (Timetal-21S), a metastable #beta#-titanium alloy, is a candidate material for titanium matrix composite structures in hydrogen-fueled hypersonic planes because of its excellent formability and adequate mechanical properties in the 500--800 C temperature range. The alloy is strengthened through the precipitation of fine #alpha# particles in the #beta# matrix. The mechanical properties and microstructures are controlled by a solutionizing/aging heat treatment. A major concern in using titanium alloys in hydrogen service is the embrittlement caused by the precipitation of hydrides. It is believed that the large solubility of hydrogen in the #beta#-phase would preclude the precipitation of hydrides in Beta titanium alloys, especially at low hydrogen pressures. However, depending on the hydrogen content, a shift in the ductile/brittle transition temperatures to levels much higher than room temperature has been reported for Timetal-21S alloy. The ...

Energy Technology Data Exchange (ETDEWEB)

Private transfers of capital from the Organization of Petroleum Exporting Countries (OPEC) to developing countries are intended to complement private transfers from the Organization of Economic Cooperation and Development (OECD) by tapping the emerging capital markets in the Middle East. Developing countries will be able to diversify their borrowing and gain additional financing. The long-term investment of oil-producing countries will benefit and the pressures on the banking institutions to recycle funds will lessen. Middle East capital markets include international loans and international bonds. The history of the Kuwaiti dinar (KD) bond market, with its advantages for both investors and borrowers, illustrates the successful development of a capital market. Financial intermediation needs to be improved, however, if the Middle East is to become efficient enough to compete with the Euromarkets. Efficiency will require different measures and should reflect ...

Energy Technology Data Exchange (ETDEWEB)

This paper describes the test results on high-temperature strength properties of fire resistant steel(FR steel) for building, the formulation, and the examples of application to member tests and actual buildings. Because of its components and manufacturing method, FR steel excels in strength at elevated temperature due to precipitation and dispersion strengthening. Tests on high temperature properties of FR steel showed that every property such as strength, stress-strain curve, elastic modulus, and creep performance at high temperature was superior to those of conventional steels. Then, it was confirmed in the tensile tests at room temperature and high temperature after heat history that FR steel could be reused after fire. It was also found in the member tests that columns and beams of FR steel could support loadings equivalent to long-term allowable unit stress until the temperature rose up to 600 centigrade. Moreover, test results could be simulated by the ...

International Nuclear Information System (INIS)

Human resource competence building and continued enhancement of performance is the most vital input for safe and reliable operations of a Nuclear Power Plant. Integrated planning leading to the decision of timely selection of optimum number of fresh people and deployment of experienced manpower with desired lead time is inevitable to achieve the above objective. For safe and reliable plant operation human performance analysis followed by suggestive measures to improve the same is needed. Corrective or strengthening input may be in terms of training, work environment, motivations, organizational culture and climate, leadership and prevailing environmental force and bio-rhythm of individuals with critical days are to be worked out The adequacy in training and development not only gives safe and reliable plant operations but results in greater employee satisfaction and self esteem as well. As of date, in the present vibrant global scenario, only the organization which ...

Science.gov (United States)

We present the latest developments for the radiation laboratory curriculum at the Department of Physics and Astronomy of Western Kentucky University. During the last decade, the Applied Physics Institute (API) at WKU accumulated various equipment for radiation experimentation. This includes various neutron sources (computer controlled d-t and d-d neutron generators, and isotopic 252 Cf and PuBe sources), the set of gamma sources with various intensities, gamma detectors with various energy resolutions (NaI, BGO, GSO, LaBr and HPGe) and the 2.5-MeV Van de Graaff particle accelerator. XRF and XRD apparatuses are also available for students and members at the API. This equipment is currently used in numerous scientific and teaching activities. Members of the API also developed a set of laboratory activities for undergraduate students taking classes from the physics curriculum (Nuclear Physics, Atomic Physics, and Radiation Biophysics). Our goal is to develop a set of radiation ...

International Nuclear Information System (INIS)

In response to European operating experience regarding Alloy 800 steam generator (SG) tube cracking, New Brunswick Power Nuclear (NBPN) recognized two important shortcomings in the industry SG technical support framework. First, information exchange networks between utilities with Alloy 800 SG tubing should be strengthened. Second and more importantly, there is a need for consistent industry guidance for Alloy 800 SG tubing degradation management, supported by clear technical bases. It is NBPN's perspective that this guidance can be improved immediately using the extensive amount of laboratory and field data that is available for Alloys 600, 690, and 800, and EPRI methodology developed to predict the performance of Alloy 690. NBPN has initiated the development of a performance-based inspection plan. This effort is based on demonstrated improvement factors for Alloy 800, defined by the EPRI approach, and described in this paper. This approach is expected to assist ...

Science.gov (United States)

pletely new PW fuel cell model had to be developed for CINDA. Several ...... following linear equation, which is used in the SINDA fuel cell model: ...

UK PubMed Central (United Kingdom)

ObjectiveTo achieve osteochondral regeneration utilizing transplantation of cartilage-lineage cells and adequate scaffolds, it is essential to characterize the behavior of transplanted...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe evolution of eukaryotic cells is widely agreed to have proceeded through a series of endosymbiotic events between larger cells and proteobacteria or cyanobacteria,...Full Text Available

Science.gov (United States)

Ti-Ag and Ti-Pd-Ag solar cell contacts structure and degradation dependence on high temperature and humidity environmental exposure

UK PubMed Central (United Kingdom)

The molecular structure, chemical properties, and biological function of the xyloglucan polysaccharide isolated from cell walls of suspension-cultured sycamore (Acer pseudoplatanus)...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

The most advanced frontier of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is represented by the use of an HLA-partially matched relative as donor. In this type of transplantation, donor-derived natural killer (NK) cells, which are alloreactive towardtoward recipient cells, significantly contribute to the eradication of leukemia blasts. Alloreactive NK cells may also kill host dendritic cells and T lymphocytes, thus preventing graft-versus-host disease and graft rejection, respectively. Sophisticated strategies of adoptive infusion of T-cell lines/clones specific for the most life-threatening pathogens (namely cytomegalovirus, Epstein-Barr virus, Aspergillus and Adenovirus) have been envisaged, and successfully tested in a few pilot trials, to protect the recipient in the...

UK PubMed Central (United Kingdom)

Conditions were found in which Chlamydomonas reinhardi exhibits a circadian alteration of its cell surface, measured as ability to stick to glass. Under these same conditions the cells...Full Text Available

Science.gov (United States)

... mast cell staining; ref. 16). The severity of structural radiation injury was assessed using a histopathological radiation injury score ... ...

UK PubMed Central (United Kingdom)

There is a requirement for a noninvasive technique to monitor stem cell differentiation. Several candidates based on optical spectroscopy are discussed in this review: Fourier transform infrared (FTIR)...Full Text Available

International Science & Technology Center (ISTC)

Morphological, Electrophysiological and Behavioral Investigations of the Nervous Tissue Developed from the Embryonic Matrix Zone Cells of the Dorsolateral Walls of Lateral Ventricles, Implanted into the Lesioned Regions of the Adult Rat's Brain

Energy Technology Data Exchange (ETDEWEB)

The present volume on modeling of batteries and fuel cells discusses the significance of the effectiveness factor for flooded porous electrodes, active pore distribution spectroscopy for characterizing porous battery electrodes, the agglomerate model for porous electrodes, and dynamic-performance measurements of battery cells for electric vehicles and other applications. Attention is given to mathematical modeling of a primary zinc/air battery, mathematical modeling of Grace Li-TiS2 cells, modeling of electrocrystallization processes in battery systems, and rotating disk electrode studies in molten Li/K carbonate eutectic. Topics addressed include the variability of nickel oxide cathode dissolution in molten carbonate fuel cells, water transport properties of fuel cell ionomers, modeling water content effects in polymer electrolyte fuel cells, and computer ...

Science.gov (United States)

Oct 15, 1985 ... Title: Laser-assisted solar cell metallization processing. No Digital Version Available: Go to Tips on Ordering ...

International Nuclear Information System (INIS)

Methods for improving the sensitivity of scintillation cells for radon concentration measurements were studied with emphasis on improving light collection efficiency. This allows the length and hence the volume of the cell to be increased. Variables studied were choice of scintillator material, its method of application and thickness, length of cell, cell material, type and configuration of reflectors, choice of photomultipliers, and factors affecting background. Response from various areas of the cell surface was studied with an alphy source and with radon filling. Coating the window with phosphor was found to be counter-productive. The optimum results obtained were with the inside of the cell (other than the window) covered with a thick layer of ZnS(Ag), or with a thick layer of reflective material coated with a thin layer of phosphor. With it, a 10 cm ...

UK PubMed Central (United Kingdom)

Proliferating cells have been immunophenotypically characterized in lymph node and bronchoalveolar lavage (BAL) samples obtained from patients with active and inactive sarcoidosis with the cell-cycle-related...Full Text Available

UK PubMed Central (United Kingdom)

PASTICCINO (PAS) genes are required for coordinated cell division and differentiation during plant development. In loss-of-function pas mutants,...Full Text Available

Science.gov (United States)

1 The Elemental Fuel Cell Model. The cell reactions are also illustrated in. Figure 1. Hydrogen is oxidized at the anode. Oxy- ...

Science.gov (United States)

Proton exchange membrane (PEM) fuel cells are energy sources that have the ... for H2 /02 PEM fuel cells because their catalysts have properties suitable for 0 ...

Science.gov (United States)

Sputtering of glass coatings on cadmium sulfide thin film solar cells

Energy Technology Data Exchange (ETDEWEB)

Substantially genetically stable continuous human cell lines derived from normal human mammary epithelial cells (HMEC) and processes for making and using the same. In a preferred embodiment, the cell lines are derived by treating normal human mammary epithelial tissue with a chemical carcinogen such as benzo(a)pyrene. The novel cell lines serve as useful substrates for elucidating the potential effects of a number of toxins, carcinogens and mutagens as well as of the addition of exogenous genetic material. The autogenic parent cells from which the cell lines are derived serve as convenient control samples for testing. The cell lines are not neoplastically transformed, although they have acquired several properties which distinguish them from their normal progenitors. 2 tabs.

Energy Technology Data Exchange (ETDEWEB)

The existence of stem cells committed to the T lymphoid lineage was deduced from studying how rat T and B stem cells differ in their expression of membrane W3/13 antigen and in their susceptibility in vivo to gamma irradiation. Stem cell activity of rat bone marrow and fetal liver was measured in long-term radiation chimeras using B and T cell alloantigenic surface markers to identify the progeny of donor cells. Monoclonal mouse anti-rat thymocyte antibody W3/13 labeled approximately 40% of fetal liver cells and 60-70% of young rat bone marrow cells (40% brightly, 25% dimly). Bright, dim, and negative cells were separated on a fluorescence-activated cell sorter. All B and T lymphoid stem cells in fetal liver were W3/13 bright, as were B lymphoid stem cells in ...

UK PubMed Central (United Kingdom)

Cells of the mononuclear phagocyte lineage have the capability to adhere to and fuse with each other and to differentiate into osteoclasts and giant cells. To investigate the macrophage adhesion/fusion...Full Text Available

Science.gov (United States)

We present a sample preparation method for measuring magnesium in individual whole lymphocytes by electron probe X-ray microanalysis. We use Burkitt's lymphoma cells in culture as the test sample and compare X-ray microanalysis of individual cells with atomic absorption analysis of pooled cell populations. We determine the magnesium peak-to-local continuum X-ray intensity ratio by electron probe X-ray microanalysis and calculate a mean cell magnesium concentration of 39 +/- 19 mmol/kg dry weight from analysis of 100 cells. We determine a mean cell magnesium concentration of 34 +/- 4 mmol/kg dry weight by atomic absorption analysis of pooled cells in three cell cultures. The mean cell magnesium concentrations determined by the two methods are not significantly different. We find a 10% coefficient of ...

Energy Technology Data Exchange (ETDEWEB)

Annual report of fuel cell projects sponsored by Department of Energy, National Energy Technology Laboratory.

Energy Technology Data Exchange (ETDEWEB)

The purpose of this review is to consider the hypothesis that cancer frequently originates from stem cells. Using the spleen transplantation assay where stem cells were transplanted in the spleen of mice lethally irradiated by ionizing radiation, the author undertook a study aimed at defining the risk of radiogenic cancer per susceptible cells with use of rat radiogenic mammary and thyroid cancers because of the high incidences of these cancers in a-bomb survivors. Measured were the number of cancer-susceptible cells initially present in the tissue, the number of such cells that survived at a given dose and the number of cancers that developed per surviving cell. Thyroid cell differentiation and proliferation in rats transplanted with thyroid cells were enhanced by thyroidectomy and low iodine diet. Further, the ...

Energy Technology Data Exchange (ETDEWEB)

Bone marrow is one of the most radiosensitive organs. Irradiation causes a marked decrease in the total number of hematopoietic cells in the bone marrow. The reticular meshwork structure of marrow stromal cells, however, is relatively resistant to irradiation. Unimpaired stromal cell structure has been thought to be a prerequisite for the repopulation of hematopoietic cells during recovery from the effects of irradiation. The reticular framework is maintained by cell adhesion apparatuses such as gap junctions. The in vitro radiobiologic survival values of a cloned stromal cell line, H-1/A, were studied (n = 1.8, D0 = 138 cGy). Radiation doses of up to 4000 cGy had no detectable effects on the production of colony-stimulating factor 1. H-1/A cells communicate with each other via gap junctions as determined by the sensitive dye-transfer ...

Energy Technology Data Exchange (ETDEWEB)

The cell is modeled as an ellipsoid with shell and the surface stress distribution calculated by means of the Maxwell Stress Tensor. The cell membrane is treated as incompressible material having both bending and shear energies of deformation. Employing the principle of virtual work, cell volume (and hence shape) is computed as a function of the external field strength and orientation with respect to the field. The following results were obtained: (1) The surface stresses that develop or the cell membrane are distributed having both normal and tangential components that act together to produce a rounding of the cell. (2) If the tangential component of the stress is ignored, then higher field strengths are needed to produce similar deformation (shape change) of cells. (3) The threshold value of the applied field, i.e, the field strength at which the volume ...

Science.gov (United States)

In order to study the neurobiological basis of seasonal changes in hippocampal structure and function, the rate of cell proliferation was examined in male and female wild meadow voles captured during different seasons. We found that the number of [3H]thymidine-labeled cells varied across the seasons and across sex in the meadow vole. Non-breeding female meadow voles had a higher rate of cell proliferation and cell death than males captured during either season or breeding females. These seasonal changes in the female meadow vole were associated with both fluctuating levels of adrenal steroids and gonadal steroids. Estradiol level was highly correlated with both the number of [3H]thymidine-labeled cells and the number of pyknotic cells in female meadow voles, with high levels of estradiol being associated with low levels of cell proliferation ...

UK PubMed Central (United Kingdom)

Hyperosmotic stress is known to significantly enhance net uptake of inorganic ions into plant cells. Direct evidence for cell turgor recovery via such a mechanism, however, is still lacking. In the...Full Text Available

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No Abstract Available

International Nuclear Information System (INIS)

... cadmium sulfides communications electrons performance testing physical

Science.gov (United States)

... prominent example today, perhaps, is the issue of stem cell research, but there is a whole list of issues ... ...

UK PubMed Central (United Kingdom)

Epidermal gamma delta T cells (γδ T) and Langerhans cells (LC) are immune cells altered by exposure to ultraviolet radiation (UVB), a powerful stressor resulting in immune suppression....Full Text Available

KoreaScience (Korea)

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DEFF Research Database (Denmark)

Udgivelsesdato: 2002-May

KoreaScience (Korea)

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DEFF Research Database (Denmark)

Udgivelsesdato: MAR

KoreaScience (Korea)

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Science.gov (United States)

No abstract prepared.

J-STORE (Japan)

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KoreaScience (Korea)

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DEFF Research Database (Denmark)

Udgivelsesdato: 1988-Jul

Science.gov (United States)

NASA's Ames Research Center awarded Ciencia, Inc., a Small Business Innovation Research contract to

UK PubMed Central (United Kingdom)

IntroductionThe phenotypic and functional differences between cells that initiate human breast tumors (cancer stem cells) and those that comprise the tumor bulk are difficult to...Full Text Available

Norwegian Open Research Archives (NORA)

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KoreaScience (Korea)

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UK PubMed Central (United Kingdom)

Murine embryonic stem (ES) cells have unusually long telomeres, much longer than those in embryonic tissues. Here we address whether hyper-long telomeres are a natural property of pluripotent stem cells,...Full Text Available

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Not Available

KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

The transformation of two different types of glial cells has been studied using an in vivo-/in vitro model and a complete in vitro model. The purpose of the study and to define in vitro model systems is to study the the neoplastic transformation of pure populations of glial cells. Data are presented to demonstrate that the transformed cells are glial and tumorigenic. (ACR)

KoreaScience (Korea)

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UK PubMed Central (United Kingdom)

BackgroundAberrant CD40 ligand (CD154) expression occurs on both T cells and B cells in human lupus patients, which is suggested to enhance B cell CD40 signaling and play a role...Full Text Available

KoreaScience (Korea)

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KoreaScience (Korea)

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British Library Electronic Table of Contents (United Kingdom)

Sphere-forming abilities in culture condition are considered a hallmark of cancer stem-like cells, which represents tumor cell invasiveness and stem-like characteristics. We aimed to show that the sphere-forming subpopulation of human malignant melanoma cell line WM-266-4 acts differently to zebrafish embryo extracts compared with their bulk counterpart. Spheres were maintained in neural stem cell culture conditions. The embryos of zebrafish at specific developmental stages were collected and the extracts were purified under 100 kDa. Spheres were treated with embyo extracts and proliferation assay and immunocytochemistry were conducted. Spheroid cells expressed nestin and epidermal growth factor receptor (EGFR) but not melanoma antigen recognized by T-cells (MART)1, indicating their stem-l...

British Library Electronic Table of Contents (United Kingdom)

A numerical model is developed to study electrolyte dependent kinetics in fuel cells. The model is based on the Poisson-Nernst-Planck (PNP) and generalized-Frumkin-Butler-Volmer (gFBV) equations, and is used to understand how the diffuse layer and ionic transport play a role in the performance difference between acidic and alkaline systems. The laminar flow fuel cell (LFFC) is used as the model fuel cell architecture to allow for the appropriate comparison of equivalent acidic and alkaline systems. We study the overall cell performance and individual electrode polarizations of acidic and alkaline fuel cells for both balanced and unbalanced electrode kinetics as well as in the presence of transport limitations. The results predict cell behavior based on electrolyte composition that strongly...

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...Polymer Fuel Cells Challenge Publications News Events Login Register Search Content type All Web pages Case studies Publications News Video Home ...Buildings Carbon capture & storage Combined heat & power Electricity transmission & distribution Energy storage Fuel cells Geothermal Hydroelectric Hydrogen Industry Lighting Marine Metering Nuclear Solar Transport Wind ...Home Emerging technologies Current focus areas Polymer Fuel Cell Challenge Polymer Fuel Cells Challenge The objective of the Polymer Fuel Cells Challenge is to develop,...prove and commercialise novel polymer fuel cell technologies that have the potential to deliver a step-change in overall system cost. What are ...