International Nuclear Information System (INIS)

2001 p. 267-268 Brazil Perry, Katia SP Ferreira, Andre RG Amorim, Mauro

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Total synthesis of cis-solamin A was accomplished without using protecting groups starting from (-)-muricatacin in 11 steps with an overall yield of 4.5%. The backbone of cis-solamin A was constructed by olefin cross-metathesis between the tetrahydrofuran moiety and g-lactone moiety. An enzymatic kinetic transesterification procedure was successfully applied to the synthesis of an optically pure g-lactone moiety.

UK PubMed Central (United Kingdom)

U.v.-visible-absorption and e.p.r. spectroscopy were used to study the type 2 and type 3 copper centres in the mercury derivative of laccase. After treatment with peroxide the mercury derivative of...Full Text Available

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The 1,3-dipolar cyclo addition reactions between benzyl azide and the alpha,beta-unsaturated lactones crotonolactone, alpha-methylenebutyrolactone and Beta-angelica lactone have been performed. The best yields of cycloadducts were obtained by working without solvent, at 60 degree centigree in a sealed tube under nitrogen atmosphere. (3aRS,6aSR)-1-Benzyl-3 a, 4,6,6a-tetrahydro-1H-furo[3,4-d]-1,2,3-triazol-4-one and 3-benzyl-7-oxa-1,2,3-triazaspiro[4.4] non-1-en-6-one have been isolated in 36% and 78% yield from the reactions of the two first lactones respectively. The second product is the first example of this heterocyclic system. The reaction with Beta-angelica lactone yielded the primary cycloadducts (3aR,S,6RS,6aSR)-and (3aRS,6SR,6aSR)-1-benzyl-3a,4,6,6a-tetrahydro-6-methyl-1H-furo[3,4-d]-1,1,3-triazol-4-one and the nitrogen elimination product 4-benzylamino-5-methyl 1-2(5H)-furanone in 44%, 11%, and ...

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Human senescence marker protein 30 (SMP30), which functions enzymatically as a lactonase, hydrolyzes various carbohydrate lactones. The penultimate step in vitamin-C biosynthesis is catalyzed by this enzyme in nonprimate mammals. It has also been implicated as an organophosphate hydrolase, with the ability to hydrolyze diisopropyl phosphofluoridate and other nerve agents. SMP30 was originally identified as an aging marker protein, whose expression decreased androgen independently in aging cells. SMP30 is also referred to as regucalcin and has been suggested to have functions in calcium homeostasis. The crystal structure of the human enzyme has been solved from X-ray diffraction data collected to a resolution of 1.4 {angstrom}. The protein has a 6-bladed {beta}-propeller fold, and it contains a single metal ion. Crystal structures have been solved with the metal site bound with either a Ca{sup 2+} or a Zn{sup 2+} atom. The catalytic role of the metal ion has been ...

UK PubMed Central (United Kingdom)

1. A cell-free system, prepared from Pseudomonas N.C.I.B. 9340 grown on 4-chloro-2-methylphenoxyacetate (MCPA) was shown to catalyse the reaction sequence: 5-chloro-3-methylcatechol...Full Text Available

International Nuclear Information System (INIS)

Ring opening dynamics of diarylethene derivative (BTF6) in n-hexane are studied by femtosecond transient absorption and time resolved spontaneous fluorescence techniques. Cyclo-reversion time constant is obtained.

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In developing new brain imaging agents for single photon emission computed tomography (SPECT), we synthesized eleven radioiodinated phenoxyacetic acid derivatives and investigated the relationship between the chemical structure and in vivo characteristics. Biodistribution studies in mice revealed high initial brain uptake for all the compounds. Blood radioactivity level depended markedly upon the chemical stability of the compound. The alpha,alpha-dimethylester derivative, amide derivatives and diamine derivatives, which were stable to hydrolysis, showed low blood activity levels following intravenous administration. Disappearance of the ester and amide compounds from the brain was rapid. However, the diamine derivatives displayed improved retention in the brain. Compounds 3a and 4 possessed the best combination of high brain uptake and sufficient retention to ...

Science.gov (United States)

The thermodynamic characteristics of adsorption of proline and its hydroxy derivatives on the surface of graphitized thermal carbon black (GTCB) were calculated. The arrangement of hydroxyl groups in the amino acid molecule was shown to influence their adsorption on GTCB. The influence of internal rotation angles in proline and its hydroxy derivative molecules on their adsorption on GTCB was studied.

CERN Document Server

Kaluza-Klein higher derivative induced gravity is studied for its application in the inflationary universe. The stability of an inflationary solution in a $D+4$-dimensional anisotropic space is analyzed carefully. We show that there is two nontrivial constraints derived from the static assumptions on the $D$-dimensional scale factor $d$ and scalar field $\\psi$. We find that a physical inflationary solution is consistent with the above constraints. In addition, a compact formula for the non-redundant $4+D$ dimensional Friedmann equation is also derived for convenience. Possible implications are also discussed in this paper.

British Library Electronic Table of Contents (United Kingdom)

This paper studies the pricing of variance swap derivatives with stochastic volatility by the control variate method. A closed form solution is derived for the approximate model with deterministic volatility, which plays the key role in the paper, and an efficient control variate technique is therefore proposed when the volatility obeys the log-normal process. By the analysis of moments for the underlying processes, the optimal volatility function in the approximate model is constructed. The numerical results show the high efficiency of our method; the results coincide with the theoretical results. The idea in the paper is also applicable for the valuation of other types of variance swap, options with stochastic volatility and other financial derivatives with multi-factor models.

British Library Electronic Table of Contents (United Kingdom)

Control of human filarial infections currently depends on chemotherapeutic strategies predominantly directed at microfilariae. Doxycycline therapy in an extended daily dose regimen sterilizes and kills adult stages, but the utility of this drug for routine field use remains an issue of concern. No macrofilaricidal drugs with efficacy after one or two doses are available for use, delaying the achievement of the elimination or eradication of onchocerciasis and lymphatic filariasis. Moxidectin, a macrocyclic lactone, is currently in clinical trials for onchocerciasis. A few other drugs that have already been approved for use in veterinary practice or in human medicine for other indications are available for investigation. Early drug discovery pipelines are poorly populated and the process of ...

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pedel preo,ure. (_PD). VSO may be developed by nor_:el epeed-o-_eter means at the output. ,haft or it may be derived ...

British Library Electronic Table of Contents (United Kingdom)

The adsorption and corrosion inhibition behavior of three selected thiosemicarbazone derivatives, namely 3-pyridinecarboxaldehyde thiosemicarbazone (META), isonicotinaldehyde thiosemicarbazone (PARA) and 2-pyridinecarboxaldehyde thiosemicarbazone (ORTHO) at the nickel surface were studied electrochemically by Tafel and impedance methods and computationally by carrying out Monte Carlo searches of configurational space on nickel/thiosemicarbazone derivative system. Electrochemical measurements showed that the inhibition efficiency of these compounds increased with increase in their concentration. The recorded inhibition efficiencies of the three tested thiosemicarbazone increase in the order: META>PARA>ORTHO. Polarization studies showed that these compounds act as mixed-type inhibitors for n...

British Library Electronic Table of Contents (United Kingdom)

Density functional theory calculations were performed to study the effects of different substituents and bridge groups on the heats of formation (HOFs), thermal stability, and detonation properties for a series of diiminotetrazole derivatives. The isodesmic reaction method was employed to calculate the HOFs of the derivatives using total energies obtained from electronic structure calculations. The bond dissociation energies and bond orders for the weakest bonds were analyzed to investigate the thermal stability of the diiminotetrazole derivatives. The detonation velocities and pressures were evaluated by using the semiempirical Kamlet-Jacobs equations, based on the theoretical densities and HOFs. These results provide basic information for the molecular design of novel high-energy density...

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Lithium isotope separation by displacement chromatography is studied using fundamental principles; the equations are derived assuming theoretical stages in lithium adsorption bands. The concentration profiles in the band are calculated numerically under unsteady state.

International Nuclear Information System (INIS)

The synthesis of 3-O-sulphamoyl derivatives of 1,2:5,6-di-O-isopropylidene-#alpha#-D-glucofuranose, 1,2-O-isopropylidene-#alpha#-D-glucofuranose, and 5,6-di-O-acetyl-1,2-O-isopropylidene-#alpha#-D-glucofuranose is described. A study of the reactions of carbohydrate chlorosulphates with azide has demonstrated the relative case with which certain chlorosulphonyloxy groups may be converted into azidosulphates. These azidosulphates could have potential synthetic value if a facile method for their conversion into sulphamoyl (aminosulphate) derivatives were available, since some sulphamoyl carbohydrates have been shown to possess antibiotic and antitrypanosomal activity. This report deals with the application of sodium borohydride and platinum oxide-hydrogen to the reduction of some 3-O-azidosulphate glucofuranose derivatives. "1H-n.m.r. spectra and infrared spectra were used.

British Library Electronic Table of Contents (United Kingdom)

The molecular environment of the key subdomain IIId of the internal ribosome entry site (IRES) element of hepatitis C virus (HCV) RNA in the binary complex with the human 40S ribosomal subunit was studied. To this end, HCV IRES derivatives bearing perfluorophenylazido groups activatable by mild UV at nucleotides G263 or A275 in the subdomain IIId stem were used. They were prepared by the complementary addressed modification of the corresponding RNA transcript with alkylating oligodeoxyribonucleotide derivatives. None of the RNA derivatives were shown to be crosslinked to the 18S rRNA. It was found that the photoreactive groups of the IRES G263 and A275 nucleotides are crosslinked to ribosomal proteins S3a, S14, and S16. For the IRES derivative with the photoreactive group in nucleotide G26...

International Nuclear Information System (INIS)

The rare earth antimonates RE_3Sb_5O_1_2 constitute an isostructural series, where the rare earth site symmetry is S_4. The spectroscopic properties of pure or doped compounds of this family are studied in order to derive their energy level schemes and to simulate them through the crystal field theory, by using the approximated D_2_d potential. The paramagnetic susceptibilities are calculated with the derived wavefunctions and compared to experiment.

CERN Document Server

Dwarf galaxies are generally faint. To derive their age and metallicity distributions, it is critical to optimize the use of any collected photon. Koleva et al., using full spectrum fitting, have found strong population gradients in some dwarf elliptical galaxies. Here, we show that the population profiles derived with this method are consistent and more precise than those obtained with spectrophotometric indices. This allows studying fainter objects in less telescope time.

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Methods were developed for the separation of radioactively labeled carbohydrate components of proteoglycans by isocratic ion-moderated partition HPLC. Neutral sugars were separated after hydrolysis in trifluoroacetic acid with baseline separation between glucose, xylose, galactose, fucose, and mannose. N-Acetylneuraminic acid, N-acetylated hexosamines, glucose, galactose, and xylitol were likewise well separated from each other under isocratic elution conditions. Glucuronic acid, iduronic acid, and their lactones were separated after hydrolysis in formic acid and sulfuric acid. Glucosamine, galactosamine, galactosaminitol, and glucosaminitol were separated by HPLC on a cation exchanger with neutral buffer after hydrolysis in hydrochloric acid. THe separation techniques also proved useful in fractionation of exoglycosidase digests of O- and N-linked oligosaccharides. Separations of aldoses, hexosamines, and uronic acids were adapted to sensitive photometric ...

Science.gov (United States)

A nonlinear partial differential equation modeling the propagation of a vertical hydraulic fracture first derived by Nordgren is studied. When properly posed, Nordgren's derivation constitutes a Stefan problem and requires another boundary condition-namely, that the velocity of the fluid at the crack tip equals the velocity of crack propagation. With this addition, Nordgren's similarity solution in the no-leakoff case is perfected by a power-series solution. New shut-in solutions are derived in the large-and-no-leakoff cases where the crack of the large-leakoff shut-in solution retracts and the crack of the no-leakoff shut-in solution extends forever. This study ignores the effect of crack-tip rock strength on crack propagation.

Science.gov (United States)

In order to reduce the air concentration of (sup 3)H in the reactor buiIding of Wolsung Heavy Water Reactor, a computer code for estimation of adsorption behavior was programmed based on an equation derived for analysis of water vapor adsorption, and a ba...

UK PubMed Central (United Kingdom)

In this study, we report the physico-chemical and biological properties of a novel biodegradable composite scaffold made of nano-hydroxyapatite and natural derived polymers of chitosan and carboxymethyl...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundZhx1 to 3 (zinc-fingers and homeoboxes) form a set of paralogous genes encoding multi-domain proteins. ZHX proteins consist of two zinc fingers followed...Full Text Available

UK PubMed Central (United Kingdom)

Sustainable management of toilet waste must prevent disease transmission but allow reuse of plant nutrients. Inactivation of uterus-derived Ascaris suum eggs was studied in relation...Full Text Available

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In this work, a new class of thiadiazole derivatives, namely 3,5-bis(2-thienyl)-1,3,4-thiadiazole (2-TTH) and 3,5-bis(3-thienyl)-1,3,4-thiadiazole (3-TTH), have been studied as possible corrosion inhibitors for mild steel in molar hydrochloric acid (1M HCl). Polarisation curves and AC impedance methods have been used. These studies have shown that the thiadiazole derivatives were very good inhibitors for mild steel in 1M HCl. Comparison of results showed that 3-TTH was the best inhibitor. The potential of zero charge (PZC) of mild steel was studied by ac impedance method, and the mechanism of adsorption has been predicted. X-ray photoelectron spectroscopy surface analysis with thiadiazole derivatives shows that it chemisorbed at the mild steel/HCl interface. The adsorption of these inhibitors followed Langmuir's adsorption isotherm. The electronic ...

UK PubMed Central (United Kingdom)

Effective connectivity in brain networks can be studied using Granger causality analysis which is based on temporal precedence, while functional connectivity is usually derived using zero-lag...Full Text Available

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The objective of this work was to investigate the efficiency of imidazole and its derivatives 4-methylimidazone, 4-methyl-5-hydroxymethylimidazone, 1-phenyl-4-methylimidazone, and 1-(p-tolyl)-4-methylimidazole for corrosion inhibition of copper in 0.5 M hydrochloric acid. Corrosion inhibition was studied using potentiodynamic methods. These studies have shown that 1-(p-tolyl)-4-methylimidazole has the best inhibitory efficiency. Activation energies were obtained by measuring the temperature dependence of the corrosion current. The activation energies in the presence of the various inhibitors are low (3--5 kJ/mol), with the best inhibitor showing the highest value. The adsorptive behavior of the imidazole derivatives on the copper electrode surface follows a Freundlich-type isotherm. The standard free energies of adsorption are also low (14--16 kJ/mol), indicating that imidazole and its ...

CERN Document Server

We provide a first-principles, perturbative derivation of the AdS5/CFT4 Y-system that has been proposed to solve the spectrum problem of N=4 SYM. The proof relies on the computation of quantum effects in the fusion of some loop operators, namely the transfer matrices. More precisely we show that the leading quantum corrections in the fusion of transfer matrices induce the correct shifts of the spectral parameter in the T-system. As intermediate steps we study UV divergences in line operators up to first order and compute the fusion of line operators up to second order for the pure spinor string in AdS5xS5. We also argue that the derivation can be easily extended to other integrable models, some of which describe string theory on AdS4, AdS3 and AdS2 spacetimes.

CERN Document Server

Warm-intermediate inflationary universe models in the context of braneworld cosmologies, are studied. This study is done in the weak and strong dissipative regimes. We find that, the scalar potentials and dissipation coefficients in terms of the scalar field, evolves as type-power-law and powers of logarithms, respectively. General conditions required for these models to be realizable are derived and discussed. We also study the scalar and tensor perturbations for each regime. We use recent astronomical observations to constraint the parameters appearing in the braneworld models.

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The rare earth antimonates RE{sub 3}Sb{sub 5}O{sub 12} constitute an isostructural series, where the rare earth site symmetry is S{sub 4}. The spectroscopic properties of pure or doped compounds of this family are studied in order to derive their energy level schemes and to simulate them through the crystal field theory, by using the approximated D{sub 2d} potential. The paramagnetic susceptibilities are calculated with the derived wavefunctions and compared to experiment.

British Library Electronic Table of Contents (United Kingdom)

From the COMBO-17 digital sky survey data, 1,231 faint blue galaxies with photometric redshifts of 0.1studied the distributions of the photometric redshifts of these sample galaxies, in the conditions that the photometric redshifts are obtained respectively by using only optical data and by using both optical and near-infrared data. The results indicate that there are 183 galaxies whose photometric redshifts derived from both optical and infrared data are greater than 1.2, that the rms error of the derived photometric redshifts is 0.046, and that to increase the photometric SNR is also helpful for discriminating those misjudged low-redshift galaxies by using only the optical data. We have studied a...

International Nuclear Information System (INIS)

Full text: HMPAO, a butane monoxime derivative of propylene amine and ECD, ethyl cysteinate dimer, are currently being used as brain imaging agents. In an effort to develop new radiopharmaceuticals for imaging brain, we have synthesized amine and imine derivatives of ethyl cysteinate with butane monoxime, optimized labelling procedure with "9"9"mTc and studied the in vivo behaviour of their "9"9"mTc complexes. Imine derivative of ethyl cysteinate with butane monoxime was synthesized by refluxing equimolar amounts of butane monoxime and ethyl cystinate in dry benzene for 3 hours. The product was purified over silica with 10% ethyl acetate in chloroform as eluent. Amine derivative was prepared by reducing the imine derivative with sodium borohydride. The ligands were characterized by NMR spectroscopy and were found to be pure. The ligands were labelled with ...

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Using the PMR method the interaction of zirconium and hafnium tetrachlorides with tri.tet.butylphenyl ester of 1,2- naphthoquinonediazide (2)-5-sulfonic acid is studied. The formation of MCl/sub 4/xNQD complexes is established, the equilibrium constants and thermodynamic parameters of complexing reaction are determined. The presence of rapid ligand exchange, proceeding according to associative mechanism, is detected. The rate constants and activation energies of the exchange reaction are calculated.

UK PubMed Central (United Kingdom)

In this work we study the temperature dependence of the Soret band lineshape of the carbonmonoxy derivatives of sperm whale myoglobin, human hemoglobin, and its isolated alpha and beta subunits. To...Full Text Available

CERN Document Server

Lead tungstate crystals doped with small fractions of praesodynium or molybdenum have been tested in beams of high-energy electrons. The goal of these tests was to study the effects of such dopants on the capability to separate the signal components deriving from the Cherenkov and scintillation light generated by the beam particles. These studies were carried out in view of the possible application of such crystals in dual-readout calorimeters.

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The determination of the banned anabolic substance zeranol and the metabolites taleranol and zearalanone in bovine urine is complicated by the occurrence of the structurally-related mycotoxin zearalenone and the corresponding {alpha}- and {beta}-zearalenol metabolites which possess similar estrogenic properties. A liquid chromatography-negative ion electrospray tandem mass spectrometric method is presented for the confirmatory analysis of all six resorcylic acid lactones ('zeranols') in urine samples using deuterium-labelled internal standards. The method was validated as a confirmatory method for bovine urine samples according to new draft EU guidelines and showed good precision and linearity, and CC{alpha} and CC{beta} values of 0.02-0.30 and <1.0 ng ml{sup -1}, respectively. The applicability was demonstrated by comparing the results of an incurred sample with previous results on the same sample obtained by gas chromatography high ...

British Library Electronic Table of Contents (United Kingdom)

Abstract The objective of this study was to investigate how a combination of different scaffold architectures and rotational culture would influence the functional properties of thick cartilaginous tissues engineered using either chondrocytes or bone marrow-derived mesenchymal stem cells (BM-MSCs). Expanded porcine chondrocytes and BM-MSCs were suspended in 2% agarose and cast in custom-designed moulds to produce either regular solid or channelled construct cylinders. The study consisted of three seperate experimental arms. First, chondrocyte and BM-MSC constructs were cultured in free swelling conditions for 9 weeks. Second, constructs were subjected to rotational culture for a period of 3 weeks. Finally, BM-MSC-seeded constructs were subjected to delayed rotational culture, in which cons...

International Nuclear Information System (INIS)

The high nutrient nitrogen and organic matter contents of sewage sludge (SS) make it a potential organic fertilizer for sandy soil. In this study, "1"5N-labelled ammonium sulphate was used to investigate the availability of nitrogen from irradiated and non-irradiated sewage sludge to tomato plants. The application of sewage sludge to sandy soil increased dry matter production (DMP), nitrogen yield (NY) and nitrogen recovery (NR) over two successive years. A positive relationship was found between sludge application rate and DMP and NY. The increase was significantly higher (P=0.05) in irradiated than non-irradiated sewage sludge. Total nitrogen derived from non-irradiated sewage sludge are : 48.0, 63.7, 73.5, 105.2 Kg/ha, whereas, the total nitrogen derived from irradiated sewage sludge are: 55.1, 72.5, 88.9, 141.4 Kg/ha corresponding to application rates of 10 t/ha, 20 t/ha, 30 t/ha, respectively. This was attributed to ...

International Nuclear Information System (INIS)

Selected derivatives of cyclophosphamide (CP) metabolites were synthesized and the solution chemistry of each was studied by "3"1P nuclear magnetic resonance (NMR) spectroscopy under a standard set of reaction conditions at physiological pH (7.4) and temperature (37"0C). Complementary "2H and "1"3C NMR spectral data was obtained using isotopically ("2G and "1"3C) enriched CP metabolites. The CP derivatives were synthesized by the ozonolysis of substituted 3-butenyl phosphorodiamidates, and were isolated as analogues of either cis and trans 4-hydroperoxy-CP or aldophosphamide (AP). The relative ratios of the tautomeric species, 4-hydroxy-CP and AP, and their half-lives (T/sub 1/2/) were measured by "3"1P NMR spectroscopy. The influence of CP metabolites on perfused U-937 cells, a CP-sensitive human lymphoma, was observed by high resolution "3"1P NMR spectroscopy. In this manner, it was possible to measure, for the first ...

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Recent studies have provided data that make it possible to estimate the efficiency and cost of future beamlines using a chemical oxygen-iodine laser as a neutralizer. These studies indicate that a 400-keV neutral deuterium beam of more than 20 A will operate at an efficiency >60%, with the capital cost of the neutralizer at less than $2/W of neutral beam output. Beamlines of lower current and less energy will operate at poorer efficiencies and higher neutralizer costs per watt of neutral beam. These are estimates. As they are very sensitive to changes in the assumptions from which they were derived, they must be used with some caution. Additional studies are expected to provide more reliable estimates.

Science.gov (United States)

Steady-state and transient behavior of the longitudinally pumped semiconductor laser is theoretically investigated by using a rate-equation model with distributed gain and photon density. Conditions necessary for bistable operation are derived. Dependencies of such major switching characteristics as turn-on and turn-off powers, delay, and rise times on laser parameters are examined. Influences of spontaneous radiation, impurities, and Auger recombination are studied. The results offer an explanation for the observed nonlinear behavior of face-pumped lasers.

UK PubMed Central (United Kingdom)

Multiple memory systems are involved in parallel processing of spatial information during navigation. A series of studies have distinguished between hippocampus-dependent ‘spatial’ navigation,...Full Text Available

International Nuclear Information System (INIS)

The thermal stability of diffusion barriers is explored on the basis of Bi films at different expedients of deriving of films. The examinations were conducted on the electrostatic accelerator at KNU of name Karazin V.N. under conditions of an isothermal bakeout directly under a proton beam of 1,85 MeV energy.

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Extracts from Helichrysum caespititium were found to have antimicrobial activity. Structure elucidation of the active compound, 2-(4-methylpentanoyl)-4-(3-methylbuten-2-yl)-phloroglucinol (caespitin), by means of spectroscopic and X-ray crystallographic analyses, is described.

UK PubMed Central (United Kingdom)

Matrix metalloproteinase (MMP) plays a crucial role in periodontal disease and is up-regulated by oral Gram-negative, pathogen-derived LPS. In this study, we reported that simvastatin, a 3-hydroxyl-3-methylglutaryl-CoA...Full Text Available

UK PubMed Central (United Kingdom)

The IgG response to gp41 (envelope glycoprotein of Mr 41,000) of the human immunodeficiency virus (HIV) was studied with eight synthetic peptides derived from three different regions of the protein....Full Text Available

International Nuclear Information System (INIS)

Orbital elements are derived from new spectroscopic and photometric observations. The masses and radii are inconsistent with evolutionary tracks for single stars, but neither star fills its Roche lobe. Analysis of the circumstellar Balmer emission lines indicates that the primary is surrounded by an extensive, highly flattened disk of nonuniform density. The velocity gradient in the disk is steeper than that expected from Keplerian motion.

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Peroxisome proliferator activated receptor-{gamma} (PPAR{gamma}) regulates metabolic homeostasis and adipocyte differentiation, and it is activated by oxidized and nitrated fatty acids. Here we report the crystal structure of the PPAR{gamma} ligand binding domain bound to nitrated linoleic acid, a potent endogenous ligand of PPAR{gamma}. Structural and functional studies of receptor-ligand interactions reveal the molecular basis of PPAR{gamma} discrimination of various naturally occurring fatty acid derivatives.

International Nuclear Information System (INIS)

1 - Description of program or function: This program solves an eigenvalue problem zBx=Ax where A and B are real block tri-diagonal matrices. This eigenvalue problem is derived from a reduced set of linear resistive MHD equations which is often employed to study tokamak plasma stability problem. 2 - Method of solution: Both the determinant and inverse iteration methods are employed. 3 - Restrictions on the complexity of the problem: The eigenvalue z must be real

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In studying the absorption of carbon dioxide by absorbents impregnated with alkanol amines, researchers used a laboratory-scale packed column to determine the overall gas-phase mass-transfer coefficients and enhancement factors. A model derived for the mechanism of the chemical reaction taking place in the interfacial layer accounts for the effect of the reaction upon the absorption rate better than other models.

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The principle of operation of shaft furnaces is explained and demonstrated in four practical examples. The conditions and parameters determining coke conversion in the combustion zone and in the Boudouard reaction range are described. The combustion process is treated as a whole while the reduction process is discussed separately for the blast furnace, the cupola furnace, and the shaft furnace. The possibilities describing the Boudouard reaction as a function of the temperature level are discussed and consequences are derived for further experimental and theoretical studies.

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We discuss in detail the derivation of the leading four-nucleon force in chiral effective field theory using the method of unitary transformation. The resulting four-nucleon force is given in both momentum and configuration space. It does not contain any unknown parameters and can be used in few- and many-nucleon studies. (orig.)

International Nuclear Information System (INIS)

Tow experiments were carried out in 1981 and 1982 growth seasons at the greenhouse of the department of agriculture for soils and water researches, atomic energy authority, at inshas, to investigate the responses of two mutation derived lines of sesame and the local cultivar giza 25 to the application of micro nutrients. The possible effect of radiation on germination and growth of sesame seed was also studied in a separate experiment conducted in 1985 season, at inshas.

Energy Technology Data Exchange (ETDEWEB)

Conventional methods for calculating electricity losses in pipe-type cable systems rely heavily on data measured in lower-voltage systems in the 1950s. With the new technique developed in this study, engineers can compute power losses more precisely for cables of various configurations and voltage ratings.

British Library Electronic Table of Contents (United Kingdom)

Plants use multiple defence mechanisms comprising both constitutive and inducible barriers to prevent entering of phytopathogenic micro-organisms. In many plant species one of the most efficient responses to combat attacking microbes is the rapid synthesis of antimicrobial low molecular weight phytoalexins, for example, resveratrol, 3,5,4prime-trihydroxystilbene (1). Resveratrol and its natural derivatives, however, display only moderate antimicrobial effects. Nevertheless, resveratrol may be a useful lead structure for the chemical synthesis of antimicrobials. In this study, several series of stilbenes have been synthesized, starting from the aldehydes using Wittig reactions to access the corresponding styrenes that were subjected to Mizoroki-Heck reactions to yield the stilbenes in good ...

British Library Electronic Table of Contents (United Kingdom)

This study presents monthly estimates of groundwater anomalies in a large river basin dominated by extensive floodplains, the Negro River Basin, based on the synergistic analysis using multisatellite observations and hydrological models. For the period 2003-2004, changes in water stored in the aquifer is isolated from the total water storage measured by GRACE by removing contributions of both the surface reservoir, derived from satellite imagery and radar altimetry, and the root zone reservoir simulated by WGHM and LaD hydrological models. The groundwater anomalies show a realistic spatial pattern compared with the hydrogeological map of the basin, and similar temporal variations to local in situ groundwater observations and altimetry-derived level height measurements. Results highlight th...

International Nuclear Information System (INIS)

Oxovanadium(IV) complexes with tridentate dibasic ONO donor schiff bases derived from salicylaldehyde, 5-chlorosalicylaldehyde, 3,5-dichlorosalicylaldehyde, 5-bromosalicylaldehyde, 3-methoxysalicylaldehyde, 2-hydroxynaphthaldehyde and 2-amino-1-propanol have been prepared and characterised by elemental analysis, infrared, electronic and ESR spectra and magnetic susceptibility measurements from 83 to 297 deg K. On the basis of these studies, presence of triplet state (S=1) and a dimeric structure with singlet ground state (S=0) have been suggested. The V=0 stretching frequencies of the complexes occur around 980 cm"-"1. (M.G.B.).

Energy Technology Data Exchange (ETDEWEB)

Previous studies suggest that the radiosensitivity and origin of tissue macrophage precursors differ from those of hemopoietic macrophage colony-forming units (CFU-Ms) committed to macrophage-lineage cells. We assessed the origins of tissue macrophage colony-forming cells (M-CFCs) in mice by comparing their kinetics and radiosensitivities in the normal steady state and under the conditions of bone marrow depletion by [sup 89]Sr-administration and/or splenectomy. The results indicate that the radiosensitive peritoneal M-CFCs elicited by thioglycollate are derived from bone marrow macrophage precursors; where as alveolar M-CFCs, which are radioresistant, are self-sustained locally and independent of hemopoietic macrophage precursors. In contrast, highly radiosensitive liver M-CFCs are probably derived from CFU-Ms that appear to be propagated in the spleen in association with hemopoietic responses. (author).

British Library Electronic Table of Contents (United Kingdom)

This paper deals with steel fiber reinforced concrete mechanical static behaviour and with its classification with respect to fibers content and mix-design variations. A number of experimental tests were conducted to investigate uniaxial compressive strength and tensile strength. Different mixtures were prepared varying both mix-design and fiber length. Fibers content in volume was of 1% and 2%. Mechanical characterization was performed by means of uniaxial compression tests with the aim of deriving the ultimate compressive strength of fiber concrete. Four-point bending tests on notched specimens were carried out to derive the first crack strength and the ductility indexes. The tensile strength of steel fiber reinforced concrete (SFRC) was obtained both from an experimental procedure and b...

International Nuclear Information System (INIS)

An important early step in the assessment of ecological risks at contaminated sites is the screening of chemicals detected on the site to identify those that constitute a potential risk. Part of this screening process is the comparison of measured ambient concentrations to concentrations that are believed to be nonhazardous, termed benchmarks. This article discusses 13 methods by which benchmarks may be derived for aquatic biota and presents benchmarks for 105 chemicals. It then compares them with respect to their sensitivity, availability, magnitude relative to background concentrations, and conceptual bases. This compilation is limited to chemicals that have been detected on the US Department of Energy's Oak Ridge Reservation (ORR) and to benchmarks derived from studies of toxic effects on freshwater organisms. The list of chemicals includes 45 metals and 56 industrial organic chemicals but only four pesticides. Although ...

Science.gov (United States)

An evaluation of eastern shale oil as an asphalt additive to reduce oxidative age hardening and moisture susceptibility is being conducted. An eastern shale oil residue having a viscosity of 1.30 Pa`s at 60{degrees}C (140{degrees}F) was blended with three different petroleum-derived asphalts that are known to be very susceptible to oxidative aging. In addition, blends of the eastern shale oil residue and the petroleum-derived asphalts are being coated onto three different aggregates that are known to be susceptible to water stripping. The oxidative age hardening portion of this study is not complete at this time. To date, information has been obtained on the unaged samples and two of the aged petroleum-derived asphalts (AAD-1 and AAK-1). When complete, this data will include rheological data on the unaged, RTFO-aged, and the RTFO/PAV-aged samples and infrared data on the unaged and RTFO/PAV-aged ...

Energy Technology Data Exchange (ETDEWEB)

Short communication.

CERN Document Server

We investigate the effect of anomalous gamma-W-W couplings in e-gamma --> nu W through the angular and energy spectrum of the secondary leptons. Within the narrow-width approximation, a semi-analytical study of the secondary lepton energy-angle double distribution is considered. Utility of observables derived from this is demonstrated by considering the anomalous coupling, delta-kappa-gamma. Results of our investigation for typical ILC machine considered at Ecm = 300-1000 GeV re-affirms potential of this collider as a precision machine.

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;Table of Contents: Gaseous Pollutants Emissions from Coal Combustors and Their Control Technologies in Japan; Simultaneous Determination of Cooper (II) and Iron (III) Using 8-Quinolinol by Solvent Extraction Flow-injection Method; Fundamental Studies on Red Mud as a Catalyst for Coal Liquefaction: Studies on Active Components in Red Mud and Possibilities for Improvement of Its Catalytic Activities; Elution Behavior of Coal-derived Liquids with Sephadex LG-20; Characteristic of Activated Carbon Produced from Scrap Tires at Different Activation Temperatures; Energy Saving Snow Melting System.

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In the tests, the effects of the overhang length on the pipe whip behavior of the pipe-restraints system were studied by measuring the strains and deformations of the test pipe and restraints, and the restraints forces. The equation for predicting the maximum strain at the outer surface of the pipe was derived using a static equilibrium condition. The calculated maximum strains at the outer surface of the pipe agree fairly well with experimental data. The dynamic response analysis of the pipe-restraints system was conducted by the finite element program ADINA. The applicability of the ADINA program to the pipe whip analysis is made clear through this analysis.

International Nuclear Information System (INIS)

A study was undertaken to determine experimentally the uptake of pollutants into of the different parts of the water hyacinth (Eichhornia crassipes) found in 'Jose Antonio Alzate' dam in the State of Mexico, Mexico. There is evidence for efficient and significant root accumulation of Ti, Mn, Fe, and Ba; but in the upper parts concentrations was consistently determined by the degree of watering. However, a significant input could be derived from a common generic source, such as the atmospheric deposition. The experimental study would, therefore, indicate that water hyacinth species can be highly effective in providing a control and treatment buffer for toxic discharges to the dam. (author)

Energy Technology Data Exchange (ETDEWEB)

The objective of project is to derive the policy recommendations to improve the efficiency of CANDU plants regulation. These policy recommendations will eventually contribute to the upgrading of Korean nuclear regulatory system and safety enhancement. During the second phase of this 2 years study, following research activities were done. Review the technical basis and framework of the new Canadian Regulation System and IAEA. Analysis on the interview of Wolsung operation staffs to identify important safety issues and regulation problems experienced at operation. Providing a plan of CANDU regulation system enhancement program.

Science.gov (United States)

The sequencing and detailed comparative functional analysis of genomes of a number of select botanical models open new doors into comparative genomics among the angiosperms, with potential benefits for improvement of many orphan crops that feed large populations. In this study, a set of simple sequence repeat (SSR) markers was developed by mining the expressed sequence tag (EST) database of sorghum. Among the SSR-containing sequences, only those sharing considerable homology with rice genomic sequences across the lengths of the 12 rice chromosomes were selected. Thus, 600 SSR-containing sorghum EST sequences (50 homologous sequences on each of the 12 rice chromosomes) were selected, with the intention of providing coverage for corresponding homologous regions of the sorghum genome. Primer pairs were designed and polymorphism detection ability was assessed using parental pairs of two existing sorghum mapping populations. About 28% of these new markers detected ...

Energy Technology Data Exchange (ETDEWEB)

The terrestrial biosphere can significantly affect the exchange of water and energy at the biosphere-atmosphere interface. Additionally, the land cover type can affect regional atmospheric chemistry and climate via biogenic volatile organic carbon (VOC) emissions and their formation of secondary organic aerosols. The broad goal of this study is to investigate the impact of land cover and vegetation changes on these specific chemistry and climate effects. The Common Land Model (CLM) is used to parameterize the biosphere-atmosphere interface over the Shanghai region in China. Phase 1 of this study, described in this report, generates input parameters for this model based on a time series of actual and derived parameters. Atmospheric forcing data are generated on an hourly temporal resolution based on a 20-year series of monthly and daily averages. Surface data, including land cover/land use and soil information, are generated ...

British Library Electronic Table of Contents (United Kingdom)

A dense Pd-Ag membrane reactor (MR) with 100% hydrogen selectivity packed with either Rh/La2O3 or Rh/La2O3-SiO2 as catalysts was used to carry out the dry reforming of methane. The membrane reactor simulation was performed using a well-known reactor model. For this purpose, we employed the equations derived from complete kinetic studies of the dry reforming of methane reaction in connection with both catalysts. In addition, we developed the kinetic equation for the reverse water gas shift reaction (RWGS). The combination of detailed kinetic studies with the measured permeation flux for the Pd-Ag membrane allowed a complete comparison between experimental and simulated operation variables. The variables studied for both catalysts were methane conversion and hydrogen permeation as a function...

Energy Technology Data Exchange (ETDEWEB)

The catalytic nature of Mo(CO)/sub 6/ supported on ..gamma..-Al/sub 2/O/sub 3/, KOH-doped ..gamma..-Al/sub 2/O/sub 3/, and HY-zeolite was investigated in CO oxidation with N/sub 2/O in comparison with that of a conventional partially reduced MoO/sub 3//..gamma..-Al/sub 2/O/sub 3/ catalyst. Kinetic parameters of this reaction were obtained in the range 0 to 100/sup 0/C; the rate law r = kP/sub N/sub 2/O//sup 1/P/sub CO//sup 0/ was found on all catalysts, and the activation energy was estimated to be 9.1 kcal/mol on the Mo(CO)/sub 6/-derived catalysts and 7.1 kcal/mol on the partially reduced MoO/sub 3//..gamma..-Al/sub 2/O/sub 3/ catalyst. Maximum catalytic activities were obtained by activating the Mo(CO)/sub 6/-derived catalysts at 400/sup 0/C. To obtain similar activity on the MoO/sub 3//..gamma..-Al/sub 2/O/sub 3/ catalyst, it was necessary to reduce at 600/sup 0/C. The former catalysts were deactivated on repeating the reaction. On the ...

Energy Technology Data Exchange (ETDEWEB)

A transient stability program was developed for the Taiwan Power Company, which has a high proportion of nuclear generation in its power system. This program offers a new territory to investigate nuclear plant effects on the power system transient stability. This program also provides a high speed tool for the Taipower system operational planning. A generalized procedure of synchronous machine modeling for a large-scale stability study is presented. The merits and weaknesses of machine modeling can be comprehended through each item of this procedure. Three types of nonlinear synchronous machine modeling implemented into this stability program are derived by following this procedure. A robust subroutine was derived to perform the fourth order Runge-Kutta integration method, making the software programming neat and systematical. For simulating the nuclear plant influence on the system, this program implemented an additional ...

Energy Technology Data Exchange (ETDEWEB)

The interest in radioiodinated diamines stems from their similarity to /sup 125/I-HIPDM and to the 1-dialkvlamino-acyl-4-phenylpiperazines that the authors have previously examined as potential brain imaging agents. In this study they converted the 1-(dialkylaminoacyl)-4-phenylpiperazines to their corresponding 1-(dialkylaminoacyl) analogs via reduction with diborane in THF. Radioiodination at the no-carrier-added level with Na/sup 125/I and chloramine-T gave the final compounds, after chromatographic separation, in 30-50% yields. The tissue distributions were determined in rats at 0.25, and 4 hrs after an i.v. injection of the radiochemical. The results indicated that all of the agents were readily extracted by the brain (1.5-2.5% ID) with brain to blood ratios >20. The structure-distribution relationships for this series were, however, decidedly different from the aminoacyl compounds in that morpholino-derivatives had better uptake and ...

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In this article we derive longitudinal impedance and wake function for an undulator setup with arbitrary undulator parameter, taking into account a finite transverse size of the electron bunch. Earlier studies considered a line density-distribution of electrons instead. We focus our attention on the long-wavelength asymptote (compared with resonance wavelength), at large distance of the electron bunch from the undulator entrance compared to the overtaking length, and for large vacuumchamber size compared to the typical transverse size of the field. These restrictions define a parameter region of interest for practical applications. We calculate a closed expression for impedance and wake function that may be evaluated numerically in the most general case. Such expression allows us to derive an analytical solution for a Gaussian transverse and longitudinal bunch shape. Finally, we study the feasibility of ...

CERN Document Server

In this article we derive longitudinal impedance and wake function for an undulator setup with arbitrary undulator parameter, taking into account a finite transverse size of the electron bunch. Earlier studies considered a line density-distribution of electrons instead. We focus our attention on the long-wavelength asymptote (compared with resonance wavelength), at large distance of the electron bunch from the undulator entrance compared to the overtaking length, and for large vacuum-chamber size compared to the typical transverse size of the field. These restrictions define a parameter region of interest for practical applications. We calculate a closed expression for impedance and wake function that may be evaluated numerically in the most general case. Such expression allows us to derive an analytical solution for a Gaussian transverse and longitudinal bunch shape. Finally, we study the feasibility ...

Energy Technology Data Exchange (ETDEWEB)

Background: The effective-dose method which was proposed by the ICRP (International Commission of Radiation Protection) for the estimation of risk to the general population from occupational or environmental, low-dose radiation exposure is not adequate for estimating the risk of cancer induction by radiotherapy of malignant or nonmalignant diseases. Methods:The risk of cancer induction by radiotherapy of benign diseases should be based on epidemiologic data directly derived from follow-up studies of patients who had been given radiotherapy for nonmalignant diseases in the past. Results: Risk factors were derived from epidemiologic studies of patients treated with irradiation for nonmalignant diseases to be used for selecting treatment options and optimizing treatment procedures. Conclusion: In most cases, cancer risks estimated by the effective-dose method may overestimate the true risks by one order of ...

International Nuclear Information System (INIS)

Within the past decade two important groups of radiopharmaceuticals labelled with /sup 123/I were introduced into the clinical application opening new areas of metabolic studies in nuclear medicine: radioiodinated fatty acids were developed for metabolic studies of the myocardium and radioiodinated amphetamine derivatives were prepared for studying brain diseases by means of SPECT. It must be emphasized that the radiochemical problems with both groups of compounds are practically the same since both are radioiodinated by a nucleophilic substitution mechanism using /sup 123/I directly in its anionic form. The clinical application of brain imaging agents, particularly the one of p-/sup 123/I-iodo-N-isopropylamphetamine, is important and will presumably increase as soon as the details of the individual biochemical steps, which are involved in brain uptake mechanisms, are evaluated. It is felt that the ...

International Nuclear Information System (INIS)

The aim of the study was to assess the usefulness of artificial neural networks (ANN) application in evaluation of scintimammography in the context of clinical data in the diagnosis of breast cancer. The results produced by ANN were compared with the diagnosis of two independent observers, nuclear medicine specialists. Material and methods: The clinical data and the numerical values derived from scintimammograms of 103 patients were the material for the study. The reference method was the result of histopathology study (core biopsy and /or FNB). Results: The overall sensitivity of physician diagnosis was 78% with specificity of 72%. The ANN produced 71% sensitivity and specificity of 73%. The physicians and ANN results were not significantly different (p=0.4619). Conclusions: Artificial neutral networks are useful tool in clinical diagnosis of breast cancer. (authors)

CERN Document Server

We point out that the moduli sector of the $(2,2)$ string compactification with its nonperturbatively preserved non-compact symmetries is a fertile framework to study global topological defects, thus providing a natural source for the large scale structure formation. Based on the target space modular invariance of the nonperturbative superpotential of the four-dimensional N=1 supersymmetric string vacua, topologically stable stringy domain walls are found. They are supersymmetric solutions, thus saturating the Bogomolnyi bound. It is also shown that there are moduli sectors that allow for the global monopole-type and texture-type configurations whose radial stability is ensured by higher derivative terms.

International Nuclear Information System (INIS)

The influence of the main factors on device efficiency of pulsed liquid jet pump with gas-liquid piston is analysed, the theoretical equation and its time-averaged solution of pulsed liquid jet pump device efficiency are derived. The theoretical and experimental results show that the efficiency of transmission of energy and mass to use pulsed jet is greatly raised, compared with steady jet, in the same device of liquid jet pump. The calculating results of time-averaged efficiency of pulsed liquid jet pump are approximately in agreement with the experimental results in our and foreign countries

International Nuclear Information System (INIS)

Single photon tomography using lipophilic tracers provides tomographic representations of regional blood flow. To penetrate a healthy blood-brain barrier requires that radiotracers either are fat-soluble or have an affinity for one of the selective blood-brain barrier transport systems. In recent years there has been an increasing interest to explore the ideal physical characteristics of "9"9"mTc for diagnostic problems of brain diseases. The development of radiopharmaceuticals for brain imaging including the intensively studied "9"9"mTc-propyleneamineoxime derivatives is discussed. (author).

Energy Technology Data Exchange (ETDEWEB)

A stochastic analysis is presented of the probability of overtopping of a dam. The discussion is based on the case of a dam for a small water storage reservoir which has recently been constructed in the Saar district in the FRG. The problem is first solved by means of a simulation method. However, it is possible to describe the result of the sumulation method by means of a much simpler model which is based on a solution of the failure integral of Freudenthal for uncorrelated resistances and loads. It is shown that the actual safety of this dam against overtopping is extremely sensitive to both the operation rule for the reservoir, and the freeboard allowance. Some general conclusions are derived from this study for assisting in the ongoing discussion of dam safety. (6 figs, 1 tab, 7 refs)

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This paper describes a signal simulator which is designed to calibrate eddy current probes. By using simultaneously an excitation coil and an electrically conducting plane, the simulator can emulate signals which correspond to spot welds with different flaws. The presence of a conducting plane allows a wide variation of the amplitude and phase of the excitation coil voltage during the calibration of a probe. A mathematical model for the simulator is derived and used to study the variation of the impedance change upon the parameters of the probe. Numerical computation shows that the impedance change depends in an important way on the frequency of the excitation coil current.

International Nuclear Information System (INIS)

The partial project SR 2039/4 investigates organizational demands and factors of the man-organization interface. Thee study is divided into the sections inventory of rules and guidelines; evaluation of organizational structures and modes of operation, and working out of demand characteristics and evaluation criteria. The objective consists in representing, analyzing and evaluating the efficiency structure of sequence organization, and deriving practice-relevant concept proposals in order to optimize the man-organization interface. In this regard, the working out of control mechanisms for the evaluation of organizational sequences is of considerable importance as a kind of working aid. (orig./DG).

British Library Electronic Table of Contents (United Kingdom)

Recent research developments in common-pool resource models emphasize the importance of links with ecological systems and the presence of non-linearities, thresholds and multiple steady states. In a recent paper Kossioris et al. (2008) develop a methodology for deriving feedback Nash equilibria for non-linear differential games and apply this methodology to a common-pool resource model of a lake where pollution corresponds to benefits and at the same time affects the ecosystem services. This paper studies the structure of optimal state-dependent taxes that steer the combined economic-ecological system towards the trajectory of optimal management, and provides an algorithm for calculating such taxes.

CERN Document Server

We develop a framework based on microeconomic theory from which the ideal gas like market models can be addressed. A kinetic exchange model based on that framework is proposed and its distributional features have been studied by considering its moments. Next, we derive the moments of the CC model (Eur. Phys. J. B 17 (2000) 167) as well. Some precise solutions are obtained which conform with the solutions obtained earlier. Finally, an output market is introduced with global price determination in the model with some necessary modifications.

International Nuclear Information System (INIS)

A theoretical study of structural and electronic properties of GeC, SnC and GeSn is presented using the full potential linearized augmented plane wave method. In this approach, the generalized gradient approximation was used for the exchange-correlation potential. Results are given for lattice constant, bulk modulus and its pressure derivative in both zinc-blende and rocksalt structures. Band structure, density of states and band gap pressure coefficients in zinc-blende structure are also given. The results are compared with previous calculations and with experimental measurements.

International Nuclear Information System (INIS)

The congestion cost caused by transmission capacities and voltage limit is an important issue in a competitive electricity market. To allocate the congestion cost equitably, the active constraints in a constrained dispatch and the sequence of these constraints should be considered. A multi-stage method is proposed which reflects the effects of both the active constraints and the sequence. In a multi-stage method, the types of congestion are analysed in order to consider the sequence, and the relationship between congestion and the active constraints is derived in a mathematical way. The case study shows that the proposed method can give more accurate and equitable signals to customers. (Author)

Energy Technology Data Exchange (ETDEWEB)

Closed string tachyons have long been somewhat mysterious. We note that there is often a regime in the classical moduli space in which one can systematically compute the effective action for such fields. In this regime, the tachyon is light, and cannot be integrated out. Instead, one must consider the combined dynamics of gravitons, moduli, tachyons and other light fields. We compute the action and find that the quartic term for the tachyon is positive in the field definition where the tachyon has no derivative coupling to the radion. We study the evolution of isotropic, homogeneous configurations and find that typically the system is driven to regions where the calculation is no longer under control. (author)

British Library Electronic Table of Contents (United Kingdom)

Sustainability of irrigated agriculture in arid and semi arid lands depends, mainly on the level of soil salinity and the quality of irrigation water. Remotely sensed data can provide information about the extent of vegetated irrigated areas. Al-Hassa oasis, Saudi Arabia is probably the largest oasis in the world depends mostly on tapped ground water to irrigate mainly date palm groves for its economic survival. This study tried to investigate the extent of soil salinity and the quality of irrigation water and the relationship with vegetation growth, employing NDVI derived from Landsat satellite imagery.

Energy Technology Data Exchange (ETDEWEB)

This paper is based on research on the combustion ignition dual-fuel engine conducted at the Zhejiang Agricultural University. The properties of compressed biogas, its performance characteristics in the compression ignited dual-fuel engine as well as the possibilities and needs for its use are discussed. Using information derived from experimental data compiled by the laboratory, analyses and comparisons have been made between high- and low-pressure biogas used in the compression ignition dual-fuel engine with respect to variation of power and the corresponding characteristic curve of the engine. The economic effects of utilizing compressed biogas are also discussed. (author).

Energy Technology Data Exchange (ETDEWEB)

Aiming to understand the formation mechanism of dioxins in the iron ore sintering process, dust samples obtained from some windboxes of a commercial iron ore sintering plant have been characterized with a powder X-ray diffraction (XRD), by the transmission electron microscope (TEM) equipped with an electron energy loss spectroscopy (EELS), and by the temperature-programmed desorption (TPD) and temperature-programmed oxidation (TPO) techniques. The elemental and XRD analyses reveal that the content of the Cl present in the samples ranges from 0.075 mass%-dry to 5.1 mass%-dry and tends to be higher at smaller dust particles, and that some of the Cl exists as KCl with the average crystalline size between 40 nm and 50 nm. Dust samples also contain a significant amount of unburned carbon, and the smallest dust particles, < 500 {mu}m, show the highest C contents in many cases and consist partly of C, K, and Cl elements. The TPD and TPO experiments exhibit that the dust samples have ...

International Nuclear Information System (INIS)

A newly synthesized glycine derivative (termed GlyD), 2-(4-(dimethylamino)benzylamino)acetic acid hydrochloride, was used to inhibit uniform and pitting corrosion processes of Al in 0.50 M KSCN solutions (pH 6.8) at 25 "oC. For uniform corrosion inhibition study, Tafel extrapolation, linear polarization resistance and impedance methods were used, complemented with SEM examinations. An independent method of chemical analysis, namely ICP-AES (inductively coupled plasma atomic emission spectrometry) was also used to test validity of corrosion rate measured by Tafel extrapolation method. GlyD inhibited uniform corrosion, even at low concentrations, reaching a value of inhibition efficiency up to 97% at a concentration of 5 x 10"-"3 M. Results obtained from the different corrosion evaluation techniques were in good agreement. This new synthesized glycine derivative was also used to control pit nucleation and growth on the pitted ...

Science.gov (United States)

The purpose of this study was to use high-resolution magnetic resonance (MR) imaging combined with image analysis to investigate the three-dimensional (3D) trabecular structure, anisotropy, and connectivity of human vertebral, femoral, and calcaneal specimens. The goal was to determine whether: (a) MR-derived measures depict known skeletal-site-specific differences in architecture and orientation of trabeculae; (b) 3D architectural parameters combined with bone mineral density (BMD) improve the prediction of the elastic modulus using a fabric tensor formulation; (c) MR-derived 3D architectural parameters combined with BMD improve the prediction of strength using a multiple regression model, and whether these results corresponded to the results obtained using higher resolution depictions of trabecular architecture. A total of 94 specimens (12 x 12 x 12 mm cubes) consisting of trabecular bone only were obtained, of which ...

International Nuclear Information System (INIS)

Total body potassium (TBK), measured at different institutions, has no reference standard for comparison. A useful reference formula, however, based on body size and age, has been derived at the Brookhaven National Laboratory. This formula was used to help calibrate a simple whole body counter for measuring total potassium and applied to nutrition and hypertension studies. A sodium iodide detector was used for counting gamma rays emitted by potassium-40 to estimate TBK. The mean ratio (+/- S.D.) of adjusted TBK measurements to predicted values was 1.002 +/- 0.047. The ratio of lean body mass estimated by the TBK measurement to that derived from skin fold thickness was 1.069 +/- 0.056. In hypertensives on low dose thiazide, the ratio of TBK measurements to predicted values was 0.994 +/- 0.052. Thus, our TBK measurements were adjusted in close agreement with a predictor formula, provided higher estimates of lean body mass ...

CERN Document Server

(abridged) We present a study of stellar population of LAEs at z=4.86 in GOODS-N and its flanking field. With the publicly available IRAC data in GOODS-N and further IRAC observations in the flanking fields, we select five LAEs which are not contaminated by neighboring objects in IRAC images and construct their observed SEDs with I_c, z', IRAC 3.6micron, and 4.5micron band photometry. The SEDs cover the rest-frame UV to optical wavelengths. We derive stellar masses, ages, color excesses, and star formation rates of five LAEs using SED fitting method. Assuming the constant star formation history, we find that the stellar masses range from 10^8 to $10^{10} Msun with the median value of 2.5x10^9 Msun. The derived ages range from very young ages (7.4 Myr) to 437 Myr with a median age of 25 Myr. The color excess E(B-V) are between 0.1-0.4 mag. Star formation rates are 55-209 Msun/yr. A comparison of the stellar populations is ...

Energy Technology Data Exchange (ETDEWEB)

Airborne pollutants can cause failures in switching and computing equipment. This paper focuses on a subset of such pollutants - airborne fine particles (<2.5 [mu]m diameter). It begins by examining the extent to which different improvements in heating, ventilating and air conditioning (HVAC) systems reduce indoor concentrations of fine particles. For each modification, the consequent reduction in soiling rate is derived. The concomitant increase in operating costs is also calculated. These costs are then compared with the costs of failures in telephone switching offices, leading to estimates of failure rate reductions that would make improvements cost-effective. Finally, the reduction in failures required to offset the costs of the improvements are compared with documented differences in failure rates between unimproved and improved environments. This study suggests that, in many telephone switching offices, the added operating costs ...

CERN Document Server

Emission-line abundances have been uncertain for more than a decade due to unexplained discrepancies in the relative intensities of the forbidden lines and weak permitted recombination lines in planetary nebulae (PNe) and H II regions. The observed intensities of forbidden and recombination lines originating from the same parent ion differ from their theoretical values by factors of more than an order of magnitude in some of these nebulae. In this study we observe UV resonance line absorption in the central stars of PNe produced by the nebular gas, and from the same ions that emit optical forbidden lines. We then compare the derived absorption column densities with the emission measures determined from ground-based observations of the nebular forbidden lines. We find for our sample of PNe that the collisionally excited forbidden lines yield column densities that are in basic agreement with the column densities derived for ...

CERN Document Server

In this paper we analyze the Hilbert boundary-value problem of the theory of analytic functions for an $(N+1)$-connected circular domain. An exact series-form solution has already been derived for the case of continuous coefficients. Motivated by the study of the Hall effect in a multiply connected plate we extend these results by examining the case of discontinuous coefficients. The Hilbert problem maps into the Riemann-Hilbert problem for symmetric piece-wise meromorphic functions invariant with respect to a symmetric Schottky group. The solution to this problem is derived in terms of two analogues of the Cauchy kernel, quasiautomorphic and quasimultiplicative kernels. The former kernel is known for any symmetry Schottky group. We prove the existence theorem for the second, quasimultiplicative, kernel for any Schottky group (its series representation is known for the first class groups only). We also show that the use of ...

British Library Electronic Table of Contents (United Kingdom)

It Peripheral blood progenitor enriched CD34+ cells (PBPC) are rather often used as stem cell background in cancer patients following high dose therapy. Keeping in mind that precursor dendritic cells (DCs) originate from haematopoietic progenitor cells, purified CD34+ cells might also serve as starting cells for ex-vivo production of DC. The aim of the present study is to develop a clinical grade procedure for ex-vivo production of DC derived from enriched CD34+ cells. Various concentrations of CD34+ cells were grown in gas-permeable Teflon bags with different serum-free and serum-containing media supplemented with GM-CSF, IL-4, TNF-a, SCF, Flt-3L and INF-a. Serum-free CellGroSCGM medium for 7 days followed by CellGroDC medium in 7 days gave equal results as serum-containing medium. Follow...

International Nuclear Information System (INIS)

The specific receptor sites and the endocytosis of transferrin (Tf) are evidenced in a cell line (HT-29) derived from a human colic adenocarcinoma by means of "1"2"5I radiolabeled Tf. The receptor density is studied in undifferentiated (UD) or differentiated (D) cells with respective doubling times of about 24 hours and 46 hours. The number of binding sites for Tf is 162,000 (K_d = 7.8 nmol/l in ND cells and 68,000 (K_d = 7.40 nmol/l) in D cells. The distribution between the Tf bound to the cell surface and the internalized Tf is investigated by elimination of Tf bound to the surface by an acid wash method. The intracellular cycle of Tf seems to be characterized by a slower kinetics in UD cells. The high density of Tf receptor sites in HT-29 UD cells should allow the detection or the treatment of highly evolutive colic adenocarcinoma by means of Tf.

International Nuclear Information System (INIS)

We have begun the ExploreNEOs project in which we observe some 700 Near-Earth Objects (NEOs) at 3.6 and 4.5 ?m with the Spitzer Space Telescope in its Warm Spitzer mode. From these measurements and catalog optical photometry we derive albedos and diameters of the observed targets. The overall goal of our ExploreNEOs program is to study the history of near-Earth space by deriving the physical properties of a large number of NEOs. In this paper, we describe both the scientific and technical construction of our ExploreNEOs program. We present our observational, photometric, and thermal modeling techniques. We present results from the first 101 targets observed in this program. We find that the distribution of albedos in this first sample is quite broad, probably indicating a wide range of compositions within the NEO population. Many objects smaller than 1 km have high albedos (?>0.35), but few objects larger than 1 km have ...

Energy Technology Data Exchange (ETDEWEB)

This study was undertaken to determine if a combined treatment (marinating in natural plant extracts or vacuum) with irradiation could have a synergistic effect, in order to prevent the lipid oxidation resulting in the development of undesirable flavours. The fresh chicken legs were irradiated at 0,3 and 5 kGy. The fatty acids composition of lipids was identified using gas liquid chromatography. The effect of irradiation treatment combined with a pre-treatment on the fatty acids composition was followed. The day after irradiation, ten panallists were asked to evaluate, using the instruction scaling, the overall appearance, the odor, the flavor and the overall acceptability of the samples. The major fatty acids identified in lipids were oleic acid, palmitic acid, palmitoleic acid and stearic acid. Pre-treatments have a significant effect on linoleic acid (C18:2) and higher fatty acids. The unsaturated fatty acids derived from phospholipids ...

British Library Electronic Table of Contents (United Kingdom)

The deportation of trophoblast debris from the placenta was first documented over 100 years ago, and today we know that the deported material ranges from multinucleated syncytial knots/sprouts to trophoblast-derived nanoparticles. However little is known about the effect of trophoblast debris on maternal physiology since it is difficult to investigate these effects in vivo in women. Animal models have been reported but they have provided relatively little information. Most of our current knowledge regarding the effects of trophoblast debris on maternal systems is provided by studies using trophoblast debris obtained from in vitro models of the human placenta. Herein we review the animal models and the in vitro studies, which, between them, suggest that deported trophoblast material may pla...

International Nuclear Information System (INIS)

Reliable and consistent characterization of the stable isotope composition of atmospheric water vapour and its temporal variability are important prerequisites to the wider application of isotope mass balance methods in atmospheric and water balance studies. A new approach is proposed which utilizes standard class-A evaporation pans, which have sufficient volume to buffer short-term transient variations in atmospheric conditions, justifying the assumption of constant kinetic isotopic fractionation effects in concert with precisely measured temperature and relative humidity to derive vapour isotopic composition. The results of the studies suggest that isotopic sampling of existing, conventionally operated class-A evaporation pans could offer a straightforward and cost-effective solution to the problem of documenting the shifting isotopic distribution in atmospheric moisture

British Library Electronic Table of Contents (United Kingdom)

Although past research has reported the benefits of intuition in new product decision-making (i.e., higher quality product; enhanced customer satisfaction), intuition has largely been studied as an individual phenomenon and little work has examined the role of intuition on new product development (NPD) project teams. Furthermore, in a turbulent environment, NPD project teams may rely more on intuitive judgments, and other factors such as experience and stress may also influence the relationship between team intuition and team decision making. Drawing from the organizational design literature on creativity in decision making, this study builds a conceptual model of NPD team intuition and its effect on the team's ability to generate creative new products. We then derive hypotheses regarding ...

International Nuclear Information System (INIS)

We have studied the features of formation and the possible stationary structures of a self-consistent magnetic field in a relativistic collisionless plasma, which are characteristic of a simple geometry of the Weibel instability that is well known in the nonrelativistic case. The universal condition is established, the growth rate is determined, and the criteria of saturation of the Weibel instability are analyzed for a broad class of anisotropic particle distribution functions (for definiteness, in application to an electron-positron plasma). A nonlinear equation of the Grad-Shafranov type describing the potential current structures is derived and its solutions are analytically studied. Special attention is paid to spatially harmonic, nonlinear current configurations with parameters determined by the properties of the initial homogeneous plasma subject to the Weibel instability. It is demonstrated that the magnetic field ...

Energy Technology Data Exchange (ETDEWEB)

Radium is known to be taken up by aquatic animals, and tends to accumulate in bone, shell and exoskeleton. The most common approach to estimating the uptake of a radionuclide by aquatic animals for use in health and environmental risk assessments is the concentration factor method. The concentration factor method relates the concentration of a contaminant in an organism to the concentration in the surrounding water. Site specific data are not usually available, and generic, default values are often used in risk assessment studies. This paper describes the concentration factor method, summarizes some of the variables which may influence the concentration factor for radium, reviews reported concentration factors measured in marine environments and presents concentration factors derived from data collected in a study in coastal Louisiana. The use of generic default values for the concentration factor is also discussed.

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A series of four 125I-labeled 1-substituted-4-phenylpiperazines were prepared and evaluated in rats as potential brain imaging agents. The compounds were labeled using (125I)iodide/chloramine-T or iodine monochloride and isolated in 48-60% radiochemical yields. The tissue distribution studies indicated that a butyrophenone derivative demonstrated the best overall brain-imaging properties. Compared with the compounds having other 1-substituents this agent had a more prolonged retention of activity in the brain and higher brain-to-blood ratios over the 4-h period studied. The in vivo behavior of this agent is comparable to that of radioiodinated N-isopropyl-p-iodoamphetamine, and, because it can be labeled directly via electrophilic methods, it has substantial potential for use in brain imaging with single photon emission computed tomography.

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The PAH (polycyclic aromatic hydrocarbons) concentration in coastal zones in the Arctic were studied. Assessment in remote areas is difficult because PAHs contamination from fossil fuel discharges and combustion can be masked by PAHs from natural sources, such as oil seeps, bitumens and forest fires. It is believed that the most important source of anthropogenic PAHs in the Arctic is the long range transport of combustion emissions. A comparison study of PAH distribution between the Beaufort Sea and the Barents Sea led to the interpretation of PAH distributions in terms of potential sources and their geochemistry. PAH concentrations in the Barents Sea sediments were found to be 2 to 20 times lower than in the Beaufort Sea sediments; they are believed to be from anthropogenic sources. In the Beaufort Sea the sediments were found to have been derived from natural sources. 7 refs., 2 figs.

British Library Electronic Table of Contents (United Kingdom)

Terrain attributes derived from digital elevation models have been used widely for mapping soil organic matter (SOM). Among these attributes, the topographic wetness index (TWI), an index for quantitatively indicating the balance between water accumulation and drainage conditions at the local scale, has been shown to correlate with SOM. However, TWIs used in most studies are calculated using a single-flow-direction (SFD) algorithm, which assumes that all water from a grid cell flows into only one neighboring cell. This assumption is not always valid, especially in areas with low relief where movement of water may be divergent. To overcome this SFD limitation, a multiple-flow-direction (MFD) algorithm has been developed, which distributes flow from a grid cell to several downslope neighbors...

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Algorithms for generating new exact solutions of the Einstein-Klein-Gordon field equations, which describe inhomogeneous universes with S/sup 3/ topology of spatial sections, are developed. The known exact vacuum and still-fluid solutions with S/sup 3/ topology are used as an input. The methods developed are further applied to derive inhomogeneous generalizations of Bianchi type IX solutions and inhomogeneous S/sup 3/ Gowdy models with gravitational and scalar waves. It is shown that the new solutions, which are generalizations of the Bianchi type IX models, permit identification of the scalar field with the velocity potential of the stiff irrotational fluid. The latter result is further used to study the growth rate of density perturbations of the isotropic and anisotropic Bianchi type IX universes in a fully nonlinear relativistic regime. The role of anisotropy on the rate of growth of density perturbations is studied in ...

British Library Electronic Table of Contents (United Kingdom)

The recent breakthrough in the generation of rat embryonic stem cells (rESCs) opens the door to application of gene targeting to create models for the study of human diseases. In addition, the in vitro differentiation system from rESCs into derivatives of three germ layers will serve as a powerful tool and resource for the investigation of mammalian development, cell function, tissue repair, and drug discovery. However, these uses have been limited by the difficulty of in vitro differentiation. The aims of this study were to establish an in vitro differentiation system from rESCs and to investigate whether rESCs are capable of forming terminal-differentiated cardiomyocytes. Using newly established rESCs, we found that embryoid body (EB)-based method used in mouse ESC (mESC) differentiation...

British Library Electronic Table of Contents (United Kingdom)

Beaked whales (Ziphiidae) often show highly specialized features, involving bone morphology or structure, in the rostral region of their skulls. Previous studies revealed an extremely derived and peculiar histological structure in the rostrum of the extant Mesoplodon densirostris. In order to assess if this structure is a general feature of ziphiids, the swollen premaxillae of Aporotus recurvirostris, a Miocene species from the North Sea, were studied histologically. These bones are pachyostotic and strongly osteosclerotic. However, their structural organization is entirely different from that of M. densirostris rostrum: they are basically made of a non-remodeled, laminar tissue that was cyclically deposited by the periosteum. As compared to the generalized structure of the premaxillae of ...

International Nuclear Information System (INIS)

Fuel management simulations have been performed for 0.9% SEU CANFLEX fuel in the Wolsung-1. Based on earlier studies at AECL, the bi-directional, four-bundle-shift fuelling scheme was assumed. Time-averaged simulations resulted in an average discharge burnup of 13.0 MWd/kgU. The derived pin power envelope indicated that the peak linear element rating with CANFLEX fuel is 15% less than that obtained with 0.9% SEU 37-element fuel and there is little power boosting at high burnups. Calculated worths of the reactivity devices are sufficient to provide the control and safety requirements for CANFLEX 0.9% SEU fuel in the Wolsung-1 reactor. (Author).

CERN Document Server

A new mathematical framework is formulated to derive the effective equations of motion for the constrained quantum system which possesses an internal clock. In the realm close to classical behavior, the quantum evolution is approximated by a finite system of coupled but ordinary differential equations adhered to the weakly imposed Hamiltonian constraint. For the simplified version of loop quantum cosmology in the Bianchi I model with a free massless scalar filed, the resulting effective equations of motion affirm the bouncing scenario predicted by the previous studies: The big bang singularity is resolved and replaced by the big bounces, which take place up to three times, once in each diagonal direction, whenever the directional density approaches the critical value in the regime of Planckian density. It is also revealed that back-reaction arises from the quantum corrections and modifies the precise value of the directional density at the ...

Energy Technology Data Exchange (ETDEWEB)

We have employed Environmental Scanning Electron Microscopy (ESEM) and Energy Dispersive X-ray (EDX) analysis to study the microstructural evolution of acrylic latex stabilised with a novel polysaccharide derived from agricultural waste. The analysis revealed that the micro structure of the latex in the 'wet' state consists of individual particles and clusters. Upon evaporation a discontinuous film is formed, with voids present within its structure, which is inconsistent with the conventional descriptions of film formation. Further ESEM examination of 'dry' specimens revealed that aging resulted in the formation of dendritic structures on the surfaces of the latex films, which EDX analysis confirmed to have been formed via crystallisation of salt. The experimental evidence suggests that the clusters, which are part of the structure of the latex, may act as nucleation centres that would allow the dendrites to ...

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The receptor occupancy-biological effect relationship for muscarinic receptors in guinea pig ileal smooth muscle has been studied by comparison of radioligand binding and contractile response. Muscarinic receptors in homogenates of ileal smooth muscle were labeled with (/sub 3/H)-1-Quinuclidinyl benzilate. Treatment with propylbenzilylcholine mustard (PrBCM), to inactivate irreversibly muscarinic receptors, caused a large dose dependent rightward shift of the dose-response curve to three agonistic furtrethonium derivatives with a concomitant decrease in maximal response. Using those data, the fraction of receptors remaining unoccupied (q-values) and true affinity constants (-log K/sub A/-values) were calculated. Exposure to 20 or 60 nM PrBCM for 15 minutes resulted in a 39% and a 61% reduction in specific (/sup 3/H)-1-Quinuclidinyl benzilate binding sites respectively to be compared with a 62% and a 85% decrease expected from calculated ...

Energy Technology Data Exchange (ETDEWEB)

In our previous study, we have estimated the level of human exposure to dioxins (PCDDs, PCDFs, and Dioxin like PCBs) in Japan based on dioxins monitoring data and results of total diet studies (TDS) in fiscal 2000 (April 2000- March 2001). It has been reported that the national PCDDs/DFs emission in 2001 against the 1997 level has been reduced by approximately 77% In addition, reduction of environmental levels was reported. The enforcement of Japan's Law Concerning Special Measures against Dioxins has significant impact on the reduction of the average dioxins concentrations in the ambient air. Therefore, the transitions of Japanese dioxins exposure levels in recent years are worthy of attention. In order to determine exposure level in fiscal 2001, collection and compilation for surveillance results derived from the regular environmental monitoring under the law as well as other dioxins surveys by national and local ...

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Science.gov (United States)

The interaction of the globular protein lysozyme with silica nanoparticles of diameter 20 nm was studied in a pH range between the isoelectric points (IEPs) of silica and the protein (pH 3-11). The adsorption affinity and capacity of lysozyme on the silica particles is increasing progressively with pH, and the adsorbed protein induces bridging aggregation of the silica particles. Structural properties of the aggregates were studied as a function of pH at a fixed protein-to-silica concentration ratio which corresponds to a surface concentration of protein well below a complete monolayer in the complete-binding regime at pH > 6. Sedimentation studies indicate the presence of compact aggregates at pH 4-6 and a loose flocculated network at pH 7-9, followed by a sharp decrease of aggregate size near the IEP of lysozyme. The structure of the bridged silica aggregates was studied by cryo-transmission ...

Energy Technology Data Exchange (ETDEWEB)

The usefulness of radioiodination via demetallation of aryltrimethylsilanes was demonstrated. The radioiodination reaction was found to be very rapid and the regiospecific incorporation of radioiodine could be carried out with high radiochemical yields and high radiospecific activity. {sup 125}I-Labeled dimethylaminoethyl iodophenoxyacetate derivatives (5a-e), dimethylaminoethyl iodophenoxyacetamide derivatives (7a-c), iodophenoxyethyl ethylenediamine derivatives (9,14) and an iodophenoxyethylpiperazine derivative (18) were efficiently synthesized from the corresponding aryltrimethylsilyl intermediates (4a-e, 6a-c, 8, 13, 17) by this method. (author).

British Library Electronic Table of Contents (United Kingdom)

This study evaluated woody biomass from logging residues, small-diameter trees, mill residues, and urban waste as a feedstock for cellulosic ethanol conversion in Mississippi. The focus on Mississippi was to assess in-state regional variations and provide specific information of biomass estimates for those facilities interested in locating in Mississippi. Supply and cost of four woody biomass sources were derived from Forest Inventory Analysis (FIA) information, a recent forest inventory conducted by the Mississippi Institute for Forest Inventory, and primary production costs. According to our analysis, about 4.0 million dry tons of woody biomass are available for production of up to 1.2 billion liters of ethanol each year in Mississippi. The feedstock consists of 69% logging residues, 21%...

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to investigate the factors that affect the adoption of cloud computing by firms belonging to the high-tech industry. The eight factors examined in this study are relative advantage, complexity, compatibility, top management support, firm size, technology readiness, competitive pressure, and trading partner pressure. Design/methodology/approach - A questionnaire-based survey was used to collect data from 111 firms belonging to the high-tech industry in Taiwan. Relevant hypotheses were derived and tested by logistic regression analysis. Findings - The findings revealed that relative advantage, top management support, firm size, competitive pressure, and trading partner pressure characteristics have a significant effect on the adoption of cloud computing...

British Library Electronic Table of Contents (United Kingdom)

Background Limited data is available for investigating the long-term safety and effects of intracoronary progenitor cell therapy in patients with acute myocardial infarction (AMI). Objective To assess the clinical course, NT-proBNP and MRI data as objective markers of cardiac function of the TOPCARE-AMI patients at 5-year follow-up. Design The TOPCARE-AMI trial was the first randomized study investigating the effects of intracoronary infusion of circulating (CPC) or bone marrow-derived progenitor cells (BMC) in 59 patients with successfully reperfused AMI. Results Five-year follow-up data were completed in 55 patients, 3 patients were lost to follow-up. None of the patients showed any signs of intramyocardial calcification or tumors at 5?years. One patient died during the initial hospitali...

British Library Electronic Table of Contents (United Kingdom)

An Otto cycle engine with internal and external irreversibilities of friction and heat leakage, in which the heat transfer between the working fluid and the environment obeys linear phenomenological heat transfer law [q ?? ?(T ?1)], is studied in this paper. The optimal piston motion trajectory for maximizing the work output per cycle is derived for the fixed total cycle time and fuel consumed per cycle. Optimal control theory is applied to determine the optimal piston trajectories for the cases of with and without piston acceleration constraint on each stroke and the optimal distribution of the total cycle time among the strokes. The optimal piston motion with acceleration constraint for each stroke consists of three segments, including initial maximum acceleration and final maximum decel...

British Library Electronic Table of Contents (United Kingdom)

The double diffusive convection in a horizontal couple stress fluid saturated anisotropic porous layer, which is heated and salted from below, is studied analytically. The modified Darcy equation that includes the time derivative term is used to model the momentum equation. The critical Rayleigh number, wavenumber for stationary and oscillatory modes, and frequency of oscillations are obtained analytically using linear theory. The effect of anisotropy parameter, solute Rayleigh number, Lewis number, couple stress parameter, and Vadasz number on the stationary, oscillatory, and finite amplitude convection is shown graphically. It is found that the thermal anisotropy parameter, couple stress parameter, and solute Rayleigh number have stabilizing effect on the stationary, oscillatory, and fin...

British Library Electronic Table of Contents (United Kingdom)

The T cell receptor is a fundamental mediator of the adaptive immune responses, since TR ab on T cells recognize foreign structures (peptides derived from processed antigens) bound to the major histocompatibility complex (MHC) on APC cells. In the present study, we report the cloning of six TRB chains cDNA sequences from gilthead sea bream (Sparus aurata), a fish of high economical impact in South Mediterranean aquaculture. The V-BETA domains have the canonical features of known teleost and mammalian TR V-BETA domains and have been divided in four different subgroups. A multiple alignment of the six sea bream TRB chains with other known TRB sequences was assembled and showed the conservation of the four cysteine residues involved in disulphide bonds and of some amino acids with an importan...

Energy Technology Data Exchange (ETDEWEB)

In this work it is made a study of the structure and electric properties of chlorate polyethylene (PE-CI) with double and simple bonds obtained by continuous plasma with resistive coupling to 13.5 MHz. The synthesis conditions are power between 10 and 14 W and pressure of (6-7) x 10{sup -2} Torr. The synthesized PE-Cl in that way is soluble in acetone what indicates that probably is formed of short chains and not it shows the generalized inter crossing that is presented in some syntheses by plasma and that it can degrade the electric properties of these polymers. The IR and XPS analysis show the vibration of the C-C, C=C and C-CI bonds. The morphology of the polymer after being dissolved shows a compact and flat configuration. The electric conductivity has an approximately lineal behavior in an interval of 35 to 90% of relative humidity. (Author)

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Background Previous reports in adults have suggested that the effects experienced after cannabis use can be described in terms of positive and negative subtypes that are heritable and are associated with abuse and dependence. This study extends existing research by inclusion of adolescents and young adults in an offspring of twins design which makes it possible to take into account genetic and environmental risks for substance use disorder. Methods Data were collected from 725 twin members of the Vietnam Era Twin Registry, 839 of their 12-32 year old biological offspring and 427 mothers. Offspring who had ever used cannabis (n=464) were asked the degree to which they typically experienced 13 subjective effects shortly after using cannabis. Latent class analysis (LCA) was used to derive sub...

Energy Technology Data Exchange (ETDEWEB)

The testing of candidate fuel elements at prototypic operating conditions with respect to temperature, power density, hydrogen coolant flow rate, etc., a crucial component in the development and qualification of nuclear rocket engines based on the Particle Bed Reactor (PBR), NERVA-derivative, and other concepts. Such testing may be performed at existing reactors, or at new facilities. A scoping study has been performed to assess the feasibility of testing PBR based fuel elements at the TREAT reactor. initial results suggest that full-scale PBR, elements could be tested at an average energy deposition of {approximately}60--80 MW-s/L in the current TREAT reactor. If the TREAT reactor was upgraded to include fuel elements with a higher temperature limit, average energy deposition of {approximately}100 MW/L may be achievable.

Energy Technology Data Exchange (ETDEWEB)

A new two-body interaction recently derived for nuclei in the 0f1p shell by fitting two-body matrix elements to 494 energy levels in A=41-66 nuclei, is used to investigate the neutron-rich nuclei in the vicinity of the doubly closed nuclide {sup 48}Ca. This study is of fundamental interest in providing a test for the new effective interaction away from the stability line. Masses and binding energies are calculated for a variety of neutron-rich nuclei and compared with experimental data, where available. In addition level schemes for {sup 50-52}Ca, {sup 51-52}Sc and {sup 51-52}Ti have been calculated and are compared with available experimental data. In general a good correspondence between theory and experiment is found, but some systematic discrepancies are apparent. ((orig.)).

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT Shallow-lacustrine delta deposits of the Upper Triassic Yanchang Formation form the most important petroleum reservoir sandstone units in the Ordos Basin, China. Recent hydrocarbon exploration and outcrop studies demonstrated that shallow-lacustrine sand-rich deltas developed extensively along the gentle flanks and central part of the basin. The vertical succession of facies indicates that the Yanchang Formation records the entire lacustrine life cycle of the Late Triassic Ordos Basin. Four third-order transgressive-regressive cycles and two larger shallow-lacustrine deltaic cycles have been recognized. A process-based depositional model, derived in part from the modern Ganjiang delta in Poyang Lake, China, is used to infer the origins of the sand-rich lacustrine delta deposits. S...

CERN Document Server

UBVI CCD photometry of NGC 2353 is obtained as part of the "Sejong Open cluster Survey" (SOS). Using the photometric membership criteria we selelct probable members of the cluster. We derive the reddening and distance to the cluster, i.e. E(B-V) = 0.10 +/- 0.02 mag and 1.17 +/- 0.04 kpc, respectively. We find that the projected distribution of the probable members on the sky is elliptical in shape rather than circular. The age of the cluster is estimated to be log(age)=8.1 +/- 0.1, older than what was found in previous studies. The minimum value of binary fraction is estimated to be about 48 +/- 5 percent from a Gaussian function fit to the distribution of the distance moduli of the photometric members. Finally, we also obtain the luminosity function and the initial mass function (IMF). The slope of the IMF is Gamma = -1.3 +/- 0.2.

International Nuclear Information System (INIS)

One of the alternative ideas to solve the spent fuel issues, the partitioning and transmutation (P and T) technology has been developed for decades. Moreover, the concept of LILW production from P and T are proposed by Bowman. A PEACER (Proliferationresistant, Environmental-friendly Accident-tolerant, Continuable and Economical Reactor), based on pyrochemical process and Pb-Bi coolant transmutation reactor, has been conceptually designed to be able to convert all PWR spent fuel into low and intermediate level waste for near-surface disposal. In this study, the acceptance criteria for near-surface disposal facility is derived by the methodology for establishment of acceptance criteria. Then acceptable TRU decontamination factor (DF) and LLFP removal efficiency in order to meet acceptance criteria is evaluated

British Library Electronic Table of Contents (United Kingdom)

An hydrazone derivative, 1,2-cyclohexanedione bis-benzoyl-hydrazone (1,2-CHBBH), has been used as a selective reagent for an advanced environmental application consisting of separating the different species of nickel in natural waters by solvent extraction. The effects of pH and reagent concentration on the extraction process were studied, as well as the influence of both organic (humic acids) and inorganic ligands (Cl-). Under natural conditions, organic and inorganic nickel species presented different extraction behaviors, and the variations in extraction yields could be correlated with the concentrations of organic complexes in the samples, allowing the separation of labile and non-labile nickel species in both fresh and marine waters.

International Nuclear Information System (INIS)

A survey is given on studies of the phonon spectra of several A-15 compounds by inelastic neutron scattering on polycrystalline samples. Comparison of the results for V_3Si, V_3Ge, N_3Ga, Nb_3Sn and Nb_3Al at 297 K lead to the conclusion that the interatomic forces are to a good approximation the same for all compounds with 4.75 valence electrons but are reduced by about 20% for those with 4.5 valence electrons. For all compounds investigated a softening of the phonon frequencies on cooling is observed which is most pronounced for those materials with the highest T/sub c/ values. From a comparison of the results with the experimentally determined Eliashberg function of Nb_3Sn information is derived about the energy dependence of the electron-phonon coupling function #alpha#"2.

International Nuclear Information System (INIS)

A study was made on interaction of vanadium (4) ions with dyes-pyrogallol red, brompyrogallol red and gallein- in the range of pH = 0-6. The maximal light absorption for gallein and brompyrogallol red is observed at pH=4 and #lambda#max = 545 nm and 560 nm respectively. The compound of vanadium (4) with pyrogalloe red is characterized by the maximal light absorption at pH=5 and #lambda#max=560 nm. Component ratio in all analyzed compounds is equal to 1:2. Molar extinction coefficients for compounds with gallein, pyrogallol red and brompyrogallol red are equal to 5000, 550 and 7400, and logarithms of stability constants - to 9.27, 13.17 and 13.25 respectively.

British Library Electronic Table of Contents (United Kingdom)

The hybrid squeeze-film damper bearing with active control is proposed in this paper and the lubricating with couple stress fluid is also taken into consideration. The pressure distribution and the dynamics of a rigid rotor supported by such bearing are studied. A PD (proportional-plus-derivative) controller is used to stabilize the rotor-bearing system. Numerical results show that, due to the nonlinear factors of oil film force, the trajectory of the rotor demonstrates a complex dynamics with rotational speed ratio s. Poincare maps, bifurcation diagrams, and power spectra are used to analyze the behavior of the rotor trajectory in the horizontal and vertical directions under different operating conditions. The maximum Lyapunov exponent and fractal dimension concepts are used to determine ...

International Nuclear Information System (INIS)

Lipophilic tertiary amines attached to cylcopentadienyl technetium-99m tricarbonyl (cytectrene) have been prepared with high radiochemical yield and purity. Biodistribution studies in mice showed that ["9"9"mTc]-cytectrenes, containing in their structure an N-methylpiperidine, were accumulated in the brain up to 2.8% of injected dose with high brain-to-blood ratios at 15 min p.i. They therefore indicate some potential as brain imaging agents. It has to be pointed out that the N-methylpiperidine ester showed similar biological behaviour as the keto derivatives. This indicates that the conversion to polar metabolite(s) via hydrolysis of the ester group - as described for ["9"9"mTc]-ECD -is not essential for brain retention. (Author).

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to determine whether walking and running at different treadmill speeds resulted in different metabolic and cardiovascular responses in the vastus lateralis (VL) and lateral gastrocnemius (LG) by examining metabolite accumulation and tissue oxygen saturation. Ten healthy subjects (6 males, 4 females) completed a submaximal treadmill exercise test, beginning at 3.2?km?h?1 and increasing by 1.6?km?h?1 increments every 3?min until reaching 85% of age-predicted maximal heart rate. Muscle tissue oxygenation (SO2), total hemoglobin (HbT) and interstitial hydrogen ion concentration ([H+]) were calculated from near infrared spectra collected from VL and LG. The [H+] threshold for each muscle was determined using a simultaneous bilinear regression. Muscle and treadmil...

Energy Technology Data Exchange (ETDEWEB)

The first part of the study goes into the determination of efficient strategies for the reduction of air pollutants. The developed method is not only derived theoretically but is tested with the concrete example of emissions sources of a German state. The second part goes into the question what the government can do in order to attain that air pollution abatement measures recognized as being efficient will be put into practice. As market economy mechanisms have advantages over central state planning in the allocation of economic resources the question arises if not also for environmental protection market economy tools may contribute to an improvement of the efficiency of air pollution abatement. Therefore the suitability of different tools of environmental policy for the realization of efficient air pollution abatement is investigated and evaluated. This is again not done abstractly but with existing emission sources. (orig./HSCH). 32 figs., ...

International Nuclear Information System (INIS)

The magnetic and magnetostrictive properties of polycrystalline Co1-xMnxFe2O4 (0 ? x ? 0.4) have been studied. Although the Curie temperature decreases continuously with increasing concentration of Mn, the magnetization remains high up to x = 0.3 and unexpectedly low coercivity is observed for this composition showing an unusual magnetostrictive behaviour. This composition shows a relatively larger magnetostriction at low fields. Moreover, the strain derivative which is the slope of the magnetostriction curve at low magnetic fields is almost doubled and the field at which maximum magnetostriction is observed is reduced to almost half for 30% of Mn substitution. The results show that x ? 0.3 in Co1-xMnxFe2O4 is an optimum composition with superior magnetostrictive properties for many applications.

British Library Electronic Table of Contents (United Kingdom)

Natural rubber (NR) and its derivatives as renewable and biodegradable materials have attracted considerable attention because of the serious pollution problems caused by synthetic materials and a shortage of resources. A new semi-interpenetrating polymer network (semi-IPN) based on epoxidised natural rubber and polyvinyl alcohol containing maleic acid as a crosslinking reagent was synthesized and characterized by FTIR, XRD, SEM, swelling ratio in both distilled water and toluene, and mechanical properties. The curing time and dose of maleic acid were varied from 10 to 60min, and from 10 to 60% (w/w), respectively. An IR spectroscopic study indicated the presence of an ester linkage at 1730cm-1 in maleic acid crosslinked with PVA in semi-IPN films. In addition, the crystalline content of P...

British Library Electronic Table of Contents (United Kingdom)

Abstract -Lactoglobulin (-LG) is a lipocalin, which is the major whey protein of cow's milk and the milk of other mammals. However, it is absent from human milk. The biological function of -LG is not clear, but its potential role in carrying fatty acids through the digestive tract has been suggested. -LG has been found in complexes with lipids such as butyric and oleic acids and has a high affinity for a wide variety of compounds. Serotonin (5-hydroxytryptamine, 5-HT), an important compound found in animals and plants, has various functions, including the regulation of mood, appetite, sleep, muscle contraction, and some cognitive functions such as memory and learning. In this study, the interaction of serotonin and one of its derivatives, arachidonyl serotonin (AA-5HT), with -LG was invest...

British Library Electronic Table of Contents (United Kingdom)

Abstract Human mesenchymal stem cells (hMSCs) may be used for therapeutic applications. Culture conditions such as the serum source may impact on cell quality and the onset of replicative senescence. We have examined the effect of culturing hMSCs in autologous serum (AS) versus fetal bovine serum (FBS) on factors involved in in vitro replicative senescence. hMSCs from four donors were cultured in 10% FBS or 10% AS until they reached senescence. Cells were harvested at early passage and near senescence to study factors known to be involved in cellular senescence. The number of population doublings till senescence was similar for cells cultured in FBS, but varied greatly for hMSCs cultured in AS. FBS cells accumulated in S phase of cell cycle. This could not be explained by increased express...

Energy Technology Data Exchange (ETDEWEB)

Genetic mapping is approached using the techniques of high resolution fluorescence in situ hybridization (FISH). This technology and the results of its application are designed to rapidly generate whole genome as tool box of expressed sequence to speed the identification of human disease genes. The results of this study are intended to dovetail with and to link the results of existing technologies for creating backbone YAC and genetic maps. In the first eight months, this approach generated 60--80% of the expressed sequence map, the remainder expected to be derived through more long-term, labor-intensive, regional chromosomal gene searches or sequencing. The laboratory has made significant progress in the set-up phase, in mapping fetal and adult brain and other cDNAs, in testing a model system for directly linking genetic and physical maps using FISH with small fragments, in setting up a database, and in establishing the validity and throughput ...

International Nuclear Information System (INIS)

New Schiff base chelating ligands were synthesized by reacting equimolar quantities of 2,3-dimethyl-4-formyl-1-phenyl-3-pyrazoline-5-one and o-anisidine, p-anisidine, m-anisidine, o-toluidine, p-toluidine, m-toluidine, 2,6-xylidine or 2,4-xylidine in ethanol medium. Their subsequent reaction with gadolinium (III) nitrate hexahydrate in 2:1 molar ratio gave complexes that were characterized by elemental analyses, molar conductances, magnetic measurements, electronic and I.R. spectral studies. All the chelates were found to be non-electrolytic in nature. (author). 15 refs., 1 fig., 1 tab.

British Library Electronic Table of Contents (United Kingdom)

Extraction of 25 L fermentation broth of the newly isolated Streptomyces sp. strain TN58 and various separation and purification steps led to the isolation of five bioactive metabolites, namely brevianamide F (C1), reported from a streptomycete for the first time, N?-acetyltryptamine (C2), thiazolidomycin (C3), and two rhamnopyranosides (C4 and C5). These two rhamnopyranosides were produced directly, without precursor addition. The chemical structure of these five active compounds was established on the basis of 1H, 13C/APT and 2D NMR spectra, ESI and EI-MS data, and by comparison with data from the literature. According to the biological studies, we show in this work that the compounds C1, C2, C4 and C5 possess antimicrobial activities.

British Library Electronic Table of Contents (United Kingdom)

This paper is concerned with the study of the Electrorheological RayleighTaylor instability (ERTI) at the interface between a densely packed saturated poorly conducting couple stress porous layer accelerated by a lighter poorly conducting couple stress fluid in a thin shell in the presence of a transverse electric field and laser radiation. A simple theory based on fully developed flow approximations is used to derive the dispersion relation for the growth rate of ERTI. The cutoff and the maximum wave numbers and the corresponding maximum frequencies are obtained. It is shown that the effects of couple stress parameter and the electric field reduce the growth rate considerably compared to a non-conducting fluid in the absence of an electric field. These are favorable to control the surface...

British Library Electronic Table of Contents (United Kingdom)

Knowledge on environmental variability and how it is affected by disturbances is crucial for understanding patterns of biodiversity and determining adequate conservation strategies. The aim of this study is to assess environmental variability in patches undergoing post-fire vegetation recovery, identifying trends of change and their relevant drivers. We particularly evaluate: the value of three spectral indices derived from Landsat satellite data [Normalized Burn Ratio (NBR), Normalized Difference Vegetation Index (NDVI) and Wetness Component of the Tasseled Cap Transformation (TCW)] for describing secondary succession; the effectiveness of three metrics (diversity, evenness and richness) as indicators of patch variability; and how thematic resolution can affect the perception of environme...

British Library Electronic Table of Contents (United Kingdom)

The objective of this study is to analyze the effects of heat loss characterized by a percentage of the fuel's energy, friction and variable specific heats of working fluid on the performance of an air standard Otto cycle with a restriction of maximum cycle temperature. A more realistic and precise relationship between the fuel's chemical energy and the heat leakage that is based on a pair of inequalities is derived through the resulting temperature. The variations in power output and thermal efficiency with compression ratio, and the relations between the power output and the thermal efficiency of the cycle are presented. The results show that the power output as well as the efficiency where maximum power output occurs will increase with increase of the maximum cycle temperature. The temp...

British Library Electronic Table of Contents (United Kingdom)

Statement of problem Inadequate dimensioning of the connectors in a cantilever cross-arch fixed dental prosthesis (FDP) in perioprosthetic patients jeopardizes the prognosis of the restoration. Purpose The purpose of this study was to investigate the effect of increasing the vertical dimension (VD) on the maximum stress developed within the connectors during the static loading of a cross-arch FDP extended as a 1- and 2-unit cantilever. Material and methods Six digital models were developed, derived from a 3-dimensional (3-D) initial model. In the initial model, the teeth were prepared for metal ceramic restorations and splinted with a cross-arch FDP, extended as a 1- or 2-unit cantilever. The VDs of the connectors proximal to the retaining abutment were 3, 4, or 5 mm. A 3-D finite element ...

Energy Technology Data Exchange (ETDEWEB)

Oils, tars, and degraded oils of varying degrees of biodegradation occur in the Permian Phosphoria Formation along the eastern flank of the Wind River mountains, Wyoming, US. Biodegradation has altered the isomer distributions of steranes, the hopanes, and the mono- and triaromatised steroids in these oils. The conventional maturity parameters based on these biomarkers are of limited use in estimating their maturity. On the other hand, even in severely biodegraded oils the vanadylporphyrin distributions are unaltered. Because of this, the Porphyrin Maturity Parameter (PMP) derived from the vanadylporphyrin distribution is an ideal parameter for estimating the maturity of these oils. This study also confirms the previous observation that T[sub s] and T[sub m] are unaffected by even severe biodegradation. 14 refs., 5 figs., 2 tabs.

CERN Document Server

Disorder on the string theory landscape may significantly affect dynamics of eternal inflation leading to the possibility for some vacua on the landscape to become dynamically preferable over others. We systematically study effects of a generic disorder on the landscape starting by identifying a sector with built-in disorder -- a set of de Sitter vacua corresponding to compactifications of the Type IIB string theory on Calabi-Yau manifolds with a number of warped Klebanov-Strassler throats attached randomly to the bulk part of the Calabi-Yau. Further, we derive continuum limit of the vacuum dynamics equations on the landscape. Using methods of dynamical renormalization group we determine the late time behavior of the probability distribution for an observer to measure a given value of the cosmological constant. We find the diffusion of the probability distribution to significantly slow down in sectors of the landscape where the number of ...

Energy Technology Data Exchange (ETDEWEB)

In this paper, the multisource geoscientific data, such as TM data, NOAA data, the data of Bouguer gravity anomaly and aeromagnetic anomaly, the multisource geophysical processing methods, such as upward continuations, vertical derivative and gradient image, and synthetic image processing method - remote sensing image processing and geophysical image processing under I{sup 2}S600, are used to study the reverse faults or thrusts in the southern margin of Ordos basin, China. On the basis of these results and with geological investigation in the field, the authors have determined three thrust compression systems, named EW thrust compression system, NE thrust compression system and NW thrust compression system. These three systems reveal the regularity of geological structural evolution in the southern margin of Ordos basis and in the north side of Qinling Orogenic Belt.

Energy Technology Data Exchange (ETDEWEB)

A new method for determining the year of birth, the year of death, and hence, the age at death, of post-bomb and recently deceased elephants has been developed. The technique is based on Accelerator Mass Spectrometry radiocarbon analyses of small-sized samples extracted from along the length of a ge-line of an elephant tusk. The measured radiocarbon concentrations in the samples from a tusk can be compared to the {sup 14}C atmospheric bomb-pulse curve to derive the growth years of the initial and final samples from the tusk. Initial data from the application of this method to two tusks will be presented. Potentially, the method may play a significant role in wildlife management practices of African national parks. Additionally, the method may contribute to the underpinnings of efforts to define new international trade regulations, which could, in effect, decrease poaching and the killing of very young animals.

Science.gov (United States)

During this report period, we have obtained a model of montmorillonite clay, and this model has been of great assistance in visualizing how the chemistry of substrate molecules might be altered as it occurs on the surface of the clay. A stereochemical representation of this montmorillonite model is shown. Of particular significance, this model indicates that hydroxyl groups are located in the center of each siloxane ring on the surface of the montmorillonite clay. These hydroxyl groups might serve to bond substrate molecules to the surface of the clay. The next step in our systematic examination of the radical cation-initiated dimerization of plant monomers from the C{sub 6}-C{sub 3} pool of shikimic acid metabolites was to study the dimerization of cinnamic acid and its derivatives. In the next block of research, we examined the reaction of montmorillonite clay (K-10) with methyleugenol. 2 refs.

DEFF Research Database (Denmark)

We present a theoretical study of the resonant interaction between dynamical localized states (discrete breathers) and linear electromagnetic excitations (EE's) in Josephson junction ladders. By making use of direct numerical simulations we find that such an interaction manifests itself by resonant steps and various sharp switchings (voltage jumps) in the current-voltage characteristics. Moreover, the power of ac oscillations away from the breather center (the breather tail) displays singularities as the externally applied dc bias decreases. All these features may be mapped to the spectrum of EE's that has been derived analytically and numerically. Using an improved analysis of the breather tail, a spectroscopy of the EE's is developed, The nature of breather instability driven by localized EE's is established.

Energy Technology Data Exchange (ETDEWEB)

Gamma-aminobutyric acid type A receptor-associated protein (GABARAP) belongs to a family of small ubiquitin-like adaptor proteins implicated in intracellular vesicle trafficking and autophagy. We have used diffusion-ordered nuclear magnetic resonance spectroscopy to study the temperature and concentration dependence of the diffusion properties of GABARAP. Our data suggest the presence of distinct conformational states and provide support for self-association of GABARAP molecules. Assuming a monomer-dimer equilibrium, a temperature-dependent dissociation constant could be derived. Based on a temperature series of {sup 1}H{sup 15}N heteronuclear single quantum coherence nuclear magnetic resonance spectra, we propose residues potentially involved in GABARAP self-interaction. The possible biological significance of these observations is discussed with respect to alternative scenarios of oligomerization.

CERN Document Server

We present a single solid-state laser system to cool, coherently manipulate and detect $^{25}$Mg$^+$ ions. Coherent manipulation is accomplished by coupling two hyperfine ground state levels using a pair of far-detuned Raman laser beams. Resonant light for Doppler cooling and detection is derived from the same laser source by means of an electro-optic modulator, generating a sideband which is resonant with the atomic transition. We demonstrate ground-state cooling of one of the vibrational modes of the ion in the trap using resolved-sideband cooling. The cooling performance is studied and discussed by observing the temporal evolution of Raman-stimulated sideband transitions. The setup is a major simplification over existing state-of-the-art systems, typically involving up to three separate laser sources.

CERN Document Server

We study the spectral and temporal behavior of the High Mass X-ray Binary A 0535+26 during a `pre-outburst flare' which took place ~5 d before the peak of a normal (type I) outburst in August/September 2005. We compare the studied behavior with that observed during the outburst. We analyse RXTE observations that monitored A 0535+26 during the outburst. We complete spectral and timing analyses of the data. We study the evolution of the pulse period, present energy-dependent pulse profiles both at the initial pre-outburst flare and close to outburst maximum, and measure how the cyclotron resonance-scattering feature (hereafter CRSF) evolves. We present three main results: a constant period P=103.3960(5)s is measured until periastron passage, followed by a spin-up with a decreasing period derivative of Pdot=(-1.69+/-0.04)x10^(-8)s/s at MJD 53618, and P remains constant again at the end of the main ...

International Nuclear Information System (INIS)

Although molten carbonate fuel cells (MCFC) have been under development since the late 1950s, the operating characteristics with gases derived from coal containing a wide range of elements other than C, H, and O were not studied until the Energy Conversion Alternative Study (ECAS) was completed in the late 1970s. Since then, the work of each contractor (United Technologies, Institute of Gas Technology, General Electric, and Energy Research Corporation) has included some contaminant studies (primarily of sulfur compounds). The majority of the reported work appears to have been conducted by UTC and IGT. The results indicate that the MCFC requires removal of sulfur to ppm levels. However, because of the strong dependence on temperature, pressure, gas composition, gas utilization, cell components, and system operation (i.e. recycle, venting, gas cleanup), the tolerance limits can vary widely.

Energy Technology Data Exchange (ETDEWEB)

In this work the authors study the stabilization point of a lifted, reacting jet of nitrogen diluted methane in co-flowing air. The jet flow is acoustically forced so as to organize the large scale vortical structures. The validation of the numerical results is possible through a concurrent experimental investigation of a similar planar jet. The use of an acoustically forced planar jet allows for significant savings by the restriction of the computation to two dimensions; the model is otherwise applicable in three dimensions. The authors based their study on the following parameters, which are derived from the experimental setup: a jet width of 1.16 cm, a mean jet velocity of 0.8 m/s, and a coflow velocity of 0.1 m/s. The acoustical forcing is studied at frequencies of 7.5 MHz and 90 MHz, which have been established experimentally as being characteristic of two broad behavioral modes. The authors ...

Energy Technology Data Exchange (ETDEWEB)

The surface enhanced Raman scattering (SERS) spectra of piperidine in silver colloid solution, on roughened silver electrode and on roughened silver electrode modified with silver nanoparticles were studied, and the high-quality SERS spectra of piperidine on roughened silver electrode modified with silver nanoparticles were obtained for the first time. Surface selection rules derived from the EM enhancement model were employed to deduce piperidine orientations on the different surfaces. On the basis of this, two models of piperidine adsorbed on the surface of the silver nanoparticles were built, and DFT-B3PW91/LanL2dz was applied to calculate the Raman frequencies. It proves that, at higher potential values, the piperidine is perpendicularly standing on the roughened silver electrode surface though its lone-electron pair, but in silver colloid solution and on the silver nanoparticles modified silver electrode the piperidine molecular lies flat ...

Science.gov (United States)

Glypican-3 (GPC3), a membrane-bound heparan sulfate proteoglycan, is found to be overexpressed in hepatocellular carcinoma (HCC). The purpose of the present study was to investigate the possible role of GPC3 in the development of HCC. In this study, RNA interference (RNAi) with a GPC3 small hairpin RNA (GPC3 shRNA) was used to identify the effects of GPC3 on the regulation of malignant behaviors of HCC. MHCC97-H, a highly metastatic human HCC cell line in which GPC3 mRNA and protein levels were detected as the highest among the 4 HCC cell lines assessed in this study, and was thus selected as a cell model for in vitro and in vivo experiments. The results showed that down-regulation of GPC3 can significantly inhibit the proliferative and invasive ability of MHCC97-H. Compared with the parental HCC cells, GPC3-silenced cells exhibited attenuated capacities in developing tumors in nude mice, while the growth of tumor ...

British Library Electronic Table of Contents (United Kingdom)

The aim of this study was to evaluate cucurbitacins (Cucs) liver protective activity in vitro and conduct QSAR studies against lipophilicity and ab initio descriptors. Nine Cucs were isolated from Cucurbitaceae plants and eight prepared by C2-alkylation or C16-acylation. Ten Cucs demonstrated protective activity on human hepatocyte-derived HepG2 cells exposed to CCl4 (EC50=2.4-45.3mM) with good margin to toxicity (T/A). All Cucs exhibited anti-proliferative effect on serum-activated rat stellate cells, HSC-T6 (EC50=0.02-4.12mM) with high T/A. While silybin is nontoxic, its protection is lower compared to Cuc D (3), iso-D (4), I (5), B (11), E (12), I-Me (6), L-Me (7), and E-Me (13) on both cell lines. Strong correlations were found for lipophilicity with both protection and toxicity on Hep...

International Nuclear Information System (INIS)

Glasses in the system (1 - x) [29Na2O- 4Al2O3- 67B2O3]- xZnO (0 ? x ? 35 mol%), have been prepared by the melt quenching technique. Elastic properties, X-ray and FT-IR spectroscopic studies have been employed to study the role of ZnO on the structure of the investigated glass system. Elastic properties and Debye temperature have been investigated using sound wave velocity measurements at 4 MHz at room temperature. The results showed that the density increases and the molar volume decreases while both sound velocities and the determined glass transition temperatures decrease with increase in x. X-ray and infrared spectra of the glasses reveal that the borate network consists of diborate units and is affected by the increase in the concentration of ZnO content. These results are interpreted in terms of the decrease in the N4 values (fraction of tetrahedral coordinated boron atoms), and substitution of longer bond lengths of Zn-O in place of ...

Energy Technology Data Exchange (ETDEWEB)

The objective of our research was to obtain fundamental information regarding the functional dependence of the diffusion coefficient of coal molecules on the ratio of molecule to pore diameter. That is, the objective of our study was to examine the effect of molecule size and configuration on hindered diffusion of coal macromolecules through as porous medium. To best accomplish this task, we circumvented the complexities of an actual porous catalyst by using a well defined porous matrix with uniform capillaric pores, i.e., a track-etched membrane. In this way, useful information was obtained regarding the relationship of molecular size and configuration on the diffusion rate of coal derived macromolecules through a pore structure with known geometry. Similar studies were performed using a pellet formed of porous alumina, to provide a link between the idealized membranes and the actual complex pore structure of real catalyst ...

Energy Technology Data Exchange (ETDEWEB)

Claims of property value loss are commonly raised by homeowners when noxious facilities are sited or when new information about the hazards of existing facilities is made public. While the capitalization of externalities into land values is consistent with economic theory, empirical measurement of impacts has not generated consistent results. This is true both for hedonic measurements as well as other types of econometric analyses. While it is well established that job and site risks have similar impacts on regional labor markets, there are no studies relating the presence of a broad range of noxious facilities to local wage premiums. In contrast, this study employs an interregional framework in a hedonic analysis of both wage and property markets and considers eight different facility classifications. This paper discusses the development of the hedonic model employed in this study. It develops more fully the theoretical ...

International Nuclear Information System (INIS)

Paper describes a new procedure to synthesize a pharmaceutical containing "2"1"1At. "2"1"1At"- anion was found to bind strongly with Rh"3"+ cation complexing with a thio-ether ligand - 1,5,9,13-tetratiacyclohexadecane-3,11-diol (16-S4-diol). One made use of "1"3"1I isotope to seek for the optimal conditions of the reaction. The derived complexes were studied by means of the paper electrophoresis, the ion exchange, the surface chromatography. One studied the kinetics of "1"3"1I"- anion binding with Rh(16-S4-diol), the dependence of the yield of "1"3"1I-Rh(16-S4-diol) forming complex on the temperature. the acidity of the reaction mixture and the concentration of the reagents. On the basis of the determined conditions of the synthesis one prepared "2"1"1At-Rh(16-S4-diol) complex by more astatide ("2"1"1At"-) to the equivalent amounts of RhCl_3 and tetra-thio-ether (16-S4-diol). One studied its behaviour

Energy Technology Data Exchange (ETDEWEB)

Subsurface and surface coalfires are a serious problem in many coal-producing countries. Combustion can occur within the coal seams (underground or surface), in piles of stored coal, or in spoil dumps at the surface. While consuming a non renewable energy source, coalfires promote several environmental problems. Among all GHGs that are emitted from coalfires, CO2 is the most significant because of its high quantity. In connection to this environmental problem, the core aim of the present research is to develop a hyperspectral remote sensing and radiative transfer based model that is able to estimate CO2 concentration (ppmv) from coalfires. Since 1960s remote sensing is being used as a tool to detect and monitoring coalfires. With time, remote sensing has proven a reliable tool to identify and monitor coalfires. In the present study multi-temporal, multi-sensor and multi-spectral thermal remote sensing data are being used to detect and monitor coalfires. Unlike the ...

Science.gov (United States)

Although the German Molasse Basin can be regarded as a mature hydrocarbon province, no regional sequence stratigraphic analysis has been carried out so far. We have studied seismic lines and well data from the region between the Isar and Inn rivers (SE Germany) that have been generously supplied by German oil companies (DEE, BEB, Mobil, RWE-DEA and Wintershall). Initial work indicates that five major seismic sequences within three main depositional cycles are developed. The Alpine thrust belt to the south serves as the primary sediment source in the foreland basin. However, sedimentary infill mainly took place parallel to the basin axis. Our analysis suggests that the stratigraphic development of the Molasse Basin was mainly controlled by eustatic sea-level changes which caused the shoreline to shift in the W-E direction. The shifting of the depocenter axis in a N-S direction was controlled by the tectonic evolution of the thrust belt. The sea-level curve ...

International Nuclear Information System (INIS)

The development of leukemia and thyroid cancer is characterized by activation of the abl oncogene and ret oncogene, respectively. In order to clarify the relationship between these gene aberrations and radiation, the pro-myelogenous leukemia-derived cell line HL60 and the thyroid cancer-derived cell line 8505C, were irradiated in vitro with 100Gy of X-rays. RNA was then extracted from 10"8 cells of the respective cell lines and examined by the reverse transcription PCR method for rearrangements of abl and ret genes. Five kinds of positive bands were observed in the HL-60 cells irradiated with 100Gy of X-ray. Similarly, six positive bands were also observed in the 8505C cells irradiated with 100Gy. In vitro X-irradiation activation of oncogenes found in radiation induced cancers imply that gene rearrangement by X-rays is involved in the development of malignant tumors. Furthermore, in an experiment to detect radiation effects in A-bomb ...

Energy Technology Data Exchange (ETDEWEB)

Activation reactions of coal reject-derived char (CRC) with CO{sub 2}, H{sub 2}O and air are experimentally studied using a thermogravimetric analysis technique. The experimental kinetic data are treated via kinetic data unification based on the half-time, and the intrinsic rate constants are extracted by the modified Arrhenius plot method. The effect of structural evolution on the overall rate changes is modelled with a modified random pore model and percolation model taking into account the ash content of the coal reject char. It is found that the relative reaction rates for the reaction pairs CO{sub 2}-CRC, H{sub 2}O-CRC and air-CRC are at an increasing order of sequence at a given temperature. The effect of gaseous pressure on the reaction rate is shown to be significant for CO{sub 2}-CRC and H{sub 2}O-CRC reactions. It has shown that both models can predict well the maximum rate and the conversion at which the maximum rate occurs. The ...

Energy Technology Data Exchange (ETDEWEB)

The effects of lead on the development of the nervous system are of immediate concern to human health. While it is clear that lead can affect neuronal development at levels of exposure within the range found in the environment, the particular mechanism of the disruption is not readily ascertained. The goal of the authors research is to develop a model system in which the effects of lead on central nervous system development can be demonstrated. To study neuronal development in a system that minimizes such difficulties, the authors have grafted discrete brain regions derived from rat fetuses into the anterior chamber of the eye of adult hosts. The brain pieces continue organotypic development in the eye, but are isolated from possible secondary changes due to alterations in the development of the endocrine and other somatic systems because the adult host has these systems already fully developed. Using this system, they have discovered that lead ...

Energy Technology Data Exchange (ETDEWEB)

This report summarizes the progress made on the development of an integrated multistage fluidized bed retorting process (KENTORT II) during the period of October 1, 1992 through September 30, 1993 under Cooperative Agreement No. DE-FC21-90MC27286 with the Morgantown Energy Technology Center, US Department of Energy. The KENTORT II process includes integral fluidized bed zones for pyrolysis, gasification, and combustion of the oil shale. The purpose of this program is to design and test the KENTORT II process at the 50-lb/hr scale. The PDU was assembled, instrumented and tested during this fiscal year. Along with the major activity of commissioning the 50-lb/hr retort, work was also completed in other areas. Basic studies of the cracking and coking kinetics of model compounds in a fixed bed reactor were continued. Additionally, as part of the effort to investigate niche market applications for KENTORT II-derived products, a ...

Science.gov (United States)

Superconductivity of binary alloys spanning the A-15 compounds V/sub 3/Si, V/sub 3/Ge, V/sub 3/Ga, and V/sub 3/Al and the pseudobinary derivatives of these stoichiometric compounds was surveyed by studying samples prepared by rf-sputtering from alloy cathodes. The possible formation of the hypothetical A-15 binaries ''V/sub 3/P,'' ''V/sub 3/B,'' and ''V/sub 3/C'' and their pseudobinary formation with V/sub 3/Si was also explored. Efforts to form these hypothetical alloys were not successful. The T/sub c/'s were measured resistively and the structure and lattice constants were determined by x-ray analysis. A maximum T/sub c/ of 11.7/sup 0/K was obtained for A-15 V/sub 3/Al, and the importance of a suitable deposition temperature and high sputtering pressures was examined. It is proposed that large variations of T/sub c/ among ...

CERN Document Server

We study the stellar and dust properties of a well-defined sample of local elliptical galaxies to investigate the relationship between host galaxy properties and nuclear activity. We select a complete sample of 45 ellipticals from the Palomar spectroscopic survey of nearby galaxies, which includes 20 low-luminosity active galactic nuclei classified as LINERs and 25 inactive galaxies. Using a stellar population synthesis method, we compare the derived stellar population properties of the LINER versus the inactive subsamples. We also study the dust and stellar surface brightness distributions of the central regions of these galaxies using high-resolution images obtained with the {\\it Hubble Space Telescope}. Relative to the inactive subsample, ellipticals hosting LINERs share similar total optical and near-infrared luminosity, central stellar velocity dispersions, and nuclear stellar populations as judged from their ...