IntroductionRecent Food and Drug Administration legislation enables the mandating of product performance standards for cigarette smoke and the evaluation of manufacturers’...Full Text Available
Out of nearly 900 women in a research study of human immunodeficiency virus infection in pregnancy, 8 were subsequently found not to be infected. Misdiagnoses could have resulted from (a) laboratory...Full Text Available
Several Bartonella species have now been implicated as human pathogens. The recovery of these fastidious organisms in the clinical microbiology laboratory remains difficult, and current...Full Text Available
The purpose of this study is to evaluate the potential benefits of applying multiseam [well] completion (MSC) technology to the massive stack of low-rank coals in the Powder River Basin. As part of this, the study objectives are: Estimate how much additional CBM resource would become accessible and technically recoverable--compared to the current practice of drilling one well to drain a single coal seam; Determine whether there are economic benefits associated with MSC technology utilization (assuming its widespread, successful application) and if so, quantify the gains; Briefly examine why past attempts by Powder River Basin CBM operators to use MSC technology have been relatively unsuccessful; Provide the underpinnings to a decision whether a MSC technology development and/or demonstration effort is warranted by DOE. To a great extent, this assessment builds on the previously published study (DOE, 2002), which contains many of the key references that underlie ...
Present and future ultra-high-energy-cosmic-ray facilities (e.g., the Pierre Auger Observatory with South and North components) and TeV-gamma-ray telescope arrays (e.g., HESS/VERITAS and CTA) have the potential to set stringent indirect bounds on the nine Lorentz-violating parameters of nonbirefringent modified Maxwell theory minimally coupled to standard Dirac theory. Theoretically, the most interesting case is isotropic Lorentz violation, which is described by a single parameter [taken to vanish for the case of the standard Lorentz-invariant theory]. It appears possible to obtain in the future an upper (lower) indirect bound on this single isotropic Lorentz-violating parameter at the +10^{-21} (-10^{-17}) level. Comparison is made with existing and future direct bounds from laboratory experiments. The possible physics implications of upper bounds at the 10^{-21} level are also briefly discussed.
Transient receptor potential (TRP) ion channels have been implicated in detecting chemical, thermal and mechanical stimuli in organisms ranging from mammals to Caenorhabditis elegans....Full Text Available
BackgroundInterim analysis of accumulating trial data is important to protect participant safety during randomized controlled trials (RCTs). Data Monitoring Committees (DMCs) often...Full Text Available
1. Miniature end-plate potentials (m.e.p.p.s) were intra- and extracellularly recorded from neuromuscular junctions in rat phrenic nerve—diaphragm preparations in vitro....Full Text Available
The prevalence of obesity among children, adolescents and adults has been dramatically increasing worldwide during the last several decades. The obesity epidemic has been recognized as one of...Full Text Available
SummaryPAS domains sense oxygen, redox potential and light, and are implicated in behavior, circadian rhythmicity, development and metabolic regulation. Although PAS domains are...Full Text Available
Electronic personal health records (ePHRs) can potentially maximize access and coordination of health information and improve patient/clinician collaboration, patient self-management, and health outcomes....Full Text Available
SummaryBlastomycosis is a serious and potentially fatal infection by the thermally dimorphic fungus Blastomyces dermatitidis. PCR assays targeting the BAD-1 virulence...Full Text Available
In March 2005, the United States Coast Guard requested that Sandia National Laboratories provide a technical review and evaluation of the appropriateness and completeness of models, assumptions, analyses, and risk management options presented in the Cabrillo Port LNG Deepwater Port Independent Risk Assessment-Revision 1 (Cabrillo Port IRA). The goal of Sandia's technical evaluation of the Cabrillo Port IRA was to assist the Coast Guard in ensuring that the hazards to the public and property from a potential LNG spill during transfer, storage, and regasification operations were appropriately evaluated and estimated. Sandia was asked to review and evaluate the Cabrillo Port IRA results relative to the risk and safety analysis framework developed in the recent Sandia report, ''Guidance on Risk Analysis and Safety Implications of a Large Liquefied Natural Gas (LNG) Spill over ...
Laboratory studies were performed to support field-testing of base injection into the F-Area Seepage Basins groundwater. The general purpose of these experiments is to provide information to guide the test of base injection and to identify potential adverse effects.
BackgroundMitochondrial DNA (mtDNA) is being analyzed by an increasing number of laboratories in order to investigate its potential role as an active marker of tumorigenesis...Full Text Available
Aim To determine the fate and clinical implication of large (?2cm), non-hypervascular nodules depicted on magnetic resonance imaging (MRI) in the cirrhotic liver. Materials and methods In 21 patients with cirrhosis (14 hepatitis B, two ethanol abuse, four cryptogenic, one Wilson's disease), 25 large (?2cm in the longest dimension) non-hypervascular nodules were identified on dynamic MRI. The implications for diagnosis of the initial size, contour, and signal characteristics on MRI in addition to patients' age and cause of cirrhosis were assessed in our analysis. Results Twelve (75%) out of 16 lesions were malignant or potentially-malignant from 14 hepatitis B patients, while seven (78%) of the nine lesions from other patients were benign (p=0.016). The mean age of the patients who ha...
Anxiety disorders are a highly prevalent and disabling class of psychiatric disorders. This review focuses on new directions in neurobiological research and implications for the development of novel psychopharmacological treatments. Neuroanatomical and neuroimaging research in anxiety disorders has centered on the role of the amygdala, reciprocal connections between the amygdala and the prefrontal cortex, and, most recently, alterations in interoceptive processing by the anterior insula. Anxiety disorders are characterized by alterations in a diverse range of neurochemical systems, suggesting ample novel targets for drug therapies. Corticotropin-releasing factor (CRF) concentrations are elevated in a subset of anxiety disorders, which suggests the potential utility of CRF receptor antagoni...
The global demand for platinum has consistently outgrown supply in the past decade. This trend likely will continue and the imbalance may possibly escalate into a crisis. Platinum plays pivotal roles in both conventional automobile emissions control and the envisioned hydrogen economy. A platinum crisis would have profound implications on energy and environment. On the one hand, inadequate platinum supply will prevent widespread commercialization of hydrogen fuel-cell vehicles. On the other hand, expensive platinum may enhance the competitiveness of hybrid, plug-in hybrid, and battery-powered electric cars. Policymakers should weigh the potential impacts of a platinum crisis in energy policy.
A theoretical model is developed to explain variations in airborne gamma-ray measurements over a calibration range near Ottawa, Ontario. The gamma-ray flux from potassium and the thorium decay series showed an expected decrease with increasing soil moisture. However, the gamma-ray flux from the uranium decay series was highest in the spring when the ground was water-saturated and even covered with snow. These results are explained through the build-up of radon and its associated gamma-ray-emitting decay products in the clay soil of the calibration range with increasing soil moisture. Similar results were found from airborne measurements over other clay soils. However, measurements over sandy soils showed that the count rates from all three radio elements increased with decreasing soil moisture. This difference between soil types was attributed to the lower radon emanation of the more coarse-grained sandy soils compared to finer-grained clay soils. The theoretical and experimental ...
A theoretical model is developed to explain variations in airborne gamma-ray measurements over a calibration range near Ottawa, Ontario. The gamma-ray flux from potassium and the thorium decay series showed an expected decrease with increasing soil moisture. However, the gamma-ray flux from the uranium decay series was highest in the spring when the ground was water-saturated and even covered with snow. These results are explained through the build-up of radon and its associated gamma-ray-emitting decay products in the clay soil of the calibration range with increasing soil moisture. Similar results were found from airborne measurements over other clay soils. However, measurements over sandy soils showed that the count rates from all three radio elements increased with decreasing soil moisture. This difference between soil types was attributed to the lower radon emanation of the more coarse-grained sandy soils compared to finer-grained clay soils. The theoretical and experimental ...
SummaryNanoparticles are increasingly being used in industry. Their potential to cause adverse health effects is due to their very small particles size (less than 100nm). A review is to be carried out to explore a) the use/release of nanoparticles in industry, b) current practices to control exposure and c) the potential levels of workplace exposure. The report will contain a discussion of what is current best practice to control exposure to nanoparticles. It will also indicate where the gaps in kn [continued...]ObjectivesA written report that draws upon disparate sources of available information and uses competent occupational hygiene expertise to form expert opinion on the implications. Key measures will the demonstration reasoned arguments supported by data from both current deliberate manufacturing of nanoparticles and incident nanoparticle production. The report will include all viable occupational exposure ...
While a great deal of evidence has directly implicated the importance of O6-alkylation of guanine in the mutagenicity of alkylating agents, evidence demonstrating the oncogenic potential of this lesion...Full Text Available
PurposeOptic nerve aplasia (ONA, OMIM 165550) is a very rare unilateral or bilateral condition that leads to blindness in the affected eye, and is usually associated with other ocular...Full Text Available
DescriptionFossil fuels have a detrimental effect on the environment. They lead to the increase in atmospheric carbon dioxide which has been documented over the last 150 years. In contrast, some sources of renewable energy are near carbon neutral. Renewable energy produced from biomass constitutes such a type of energy and so has many potential advantages. The Energy White Paper (DTI et al., 2003) identifies bioenergy as an important means of meeting the Government's energy and environment objectives, in [continued...
The study has analysed the effects of various factors on hydroelectric power generation potential to include climate change/variability, water demand, and installation of proposed hydroelectric power schemes in the Zambezi River Basin. An assessment of historical (1970?2000) power potential in relation to climate change/variability at existing hydro electric power schemes(Cahora Bassa, Kariba, Kafue Gorge and Itezhi-Tezhi) in the Zambezi River Basin was conducted. The correlation of hydroelectric power potential with climate change/variability aimed at observing the link and extent of influence of the latter on the former was investigated. In order to predict the future outlook of hydro electric power potential, General Circulation Models (GCM) were used to generate projected precipitation...
The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter release and in synaptogenesis, suggesting a potential role in several neuropsychiatric diseases. The human SYN3 gene is located on chromosome 22q12-13, a candidate region implicated in previous linkage studies of schizophrenia. However, association studies of SYN3 and schizophrenia have produced inconsistent results. In this study, four SYN3 SNPs (rs133945 (-631 C>G), rs133946 (-196 G>A), rs9862 and rs1056484) were tested in three sets of totally 3759 samples that comprise 655 affected subjects and 626 controls in the Irish Case-Control Study of Schizophrenia (ICCSS), 1350 samples incorporating 273 pedigrees in the Irish Study of High D...
Describes laboratory and industrial tests on the use of lowasash sulphurous petroleum coke during reduction of barite. Shows the potential of substituting blast furnace coke with petroleum/coke fines in this process.
Potential uses of foliage and bark wastes of E. ('Mysore') hybrid in southern India for the production of cineole and oxalic acid respectively are discussed. Only certain strains are cineole-rich and these are being successfully propagated vegetatively at the authors' laboratory.
This report is directed at the commercial potential of the 17-m, 100 kW Darrieus Vertical Axis Wind Turbine (VAWT) developed under DOE funding by Sandia National laboratories (SNL) and Alcoa Laboratories. Three of the turbines have come on line over the past 14 months and long-term testing is in progress. As the first commercially adapted Darrieus turbines built by DOE, the superior cost, structural integrity, and output characteristics demonstrated by the prototypes appear particularly promising.
SUMMARY Spontaneous potentials associated with volcanic activity are often interpreted by means of the electrokinetic potential, which is usually positive in the flow direction (i.e. Zeta potential of the rock is negative). The water-rock interactions in hydrothermal zones alter the primary minerals leading to the formation of secondary minerals. This work addresses the study of calcite precipitation in a sand composed of 98 per cent quartz and 2 per cent calcite using streaming potential measurements. The precipitation of calcite as a secondary mineral phase, inferred by high calcite saturation indices and by a fall in permeability, has a significant effect on the electrokinetic behaviour, leading to a significant reduction in the Zeta potential (in absolute value) and even a change in si...
Los Alamos National Laboratory (the Laboratory) is subject to emissions reporting requirements for regulated air contaminants under Title 20 of the New Mexico Administrative Code, Chapter 2, Part 73 (20 NMAC 2.73), Notice of Intent and Emissions Inventory Requirements. The Laboratory has the potential to emit 100 tons per year of suspended particulate matter, nitrogen oxides, carbon monoxide, sulfur oxides, and volatile organic compounds. For 1998, combustion products from the industrial sources contributed the greatest amount of criteria air pollutants from the Laboratory. Research and development activities contributed the greatest amount of volatile organic compounds. Emissions of beryllium and aluminum were reported for activities permitted under 20 NMAC 2.72 Construction Permits.
This paper develops a clear procedure for solving the nonlinear Vlasov-Maxwell equations for a one-component intense charged particle beam or finite-length charge bunch propagating through a cylindrical conducting pipe (radius r = r(subscript)w = const.), and confined by an applied focusing force. In particular, the nonlinear Vlasov-Maxwell equations are Lorentz-transformed to the beam frame ('primed' variables) moving with axial velocity relative to the laboratory. In the beam frame, the particle motions are nonrelativistic for the applications of practical interest, already a major simplification. Then, in the beam frame, we make the electrostatic approximation which fully incorporates beam space-charge effects, but neglects any fast electromagnetic processes with transverse polarization (e.g., light waves). The resulting Vlasov-Maxwell equations are then Lorentz-transformed back to the laboratory frame, and properties of ...
Aluminum toxicity has been implicated in the pathogenesis of a number of clinical disorders in patients with chronic renal failure on long-term intermittent hemodialysis treatment. The predominant disorders have been those involving either bone (osteomalacic dialysis osteodystrophy) or brain (dialysis encephalopathy). In nonuremic patients, an increased brain aluminum concentration has been implicated as a neurotoxic agent in the pathogenesis of Alzheimer's disease and was associated with experimental neurofibrillary degeneration in animals. The brain aluminum concentrations of patients dying with the syndrome of dialysis encephalopathy (dialysis dementia) are significantly higher than in dialyzed patients without the syndrome and in nondialyzed patients. Two potential sources for the increased tissue content of aluminum in patients on hemodialysis have been proposed: (1) intestinal absorption from aluminum ...
This article addresses the possibility that electric utilities may not have enough generating capacity to meet the demands on their systems at some future date as a result of a recent spate of plant-construction cancellations, especially of nuclear facilities. It emphasizes that, when that time arrives, utilities will be willing to try every conceivable possibility for preserving the integrity of their systems, and offers differential pricing of electricity as one such possibility. The article also offers a regional analysis of the effect of plant cancellations and of the potential for differential pricing as a preventative of power shortages. 5 tables.
ABSTRACT: Metabolomic analysis will provide the next large set of clues to further our understanding of human health and disease. A recent study has elucidated the significant differences in the metabolomes of adipocytes, serum and an adipocyte cell line after activation of two nuclear receptors, peroxisome proliferator activated receptor ?/? (PPAR?/?) and PPAR?. These findings hold great promise for explaining fundamental differences in the mechanisms of PPAR agonists and for identifying targets for the treatment of diabetes.See related research article: http://genomebiology.com/2011/12/8/R75. PMID:21861850
The potential strategic impact of regime change in Iraq and Iran on OPEC in the long-run is explored. In the first part of the paper short overviews are given of the present international oil market; of US oil import issues and energy policy; of the strategic position of the US in the Persian Gulf and of geopolitical developments in the Persian Gulf at large. Also, attention is paid to the OPEC and the role of a 'new' Iraq. In the second part the game of 'boxed pigs' is used to explore the possible strategic impact of regime change in Iraq and possible regime change in Iran on OPEC. This exploration takes place within four possible futures for the Gulf.
Economic depreciation of similar cost recovery schemes delay cash return of investment. Such delay may require new types of securities. Due to uncertainty of regulatory action and technology over the prolonged recovery life of the projects, investors may require a higher return, thereby raising the cost of capital. Utility managements might eschew long lived investment, too, even if cost effective to the consumer. Alternatives exist that would approximate the price signals of economic depreciation without discouraging investment. The importance of upfront returns to the investment process should not be minimized. 2 figs., 3 refs. (AV)
Purpose - The purpose of this paper is to place all of the contributions to this special issue into a theoretical framework and to highlight the role that the so-called "information age mindset" has in the facilitation of employability skills. Design/methodology/approach - The paper discusses the major themes of this special issue. Findings - Undergraduate students do see the importance of technological innovation in the classroom but they see the development of experiential or work-based skills to be more important. Practical implications - Future curriculum design should consider the expectations and attitudes of the modern day undergraduate student to ensure that potential employability is maximised. Originality/value - The findings are placed into the wider context of the emerging fiel...
Computer simulations of agricultural finance and management may be helpful to students preparing for agricultural careers. Simulations would provide problem definition and problem solving in realistic interactions with complex and ambiguous situations similar to those encountered in farming. The paper describes a major financial problem for farmers, explores the implications of that problem for students, and outlines a computer-based simulation model which would give students experience in dealing with the problem. Data sources for simulations, potentials of interactive exercises among students, and advantages of using real data with existing ambiguities are described. The board game "AGRICULTURE" is discussed as a prototype for simulation. (LFL)
This is the homepage of "an Australian multi-university collaboration undertaking research on the fundamental physics and technology of building, at the atomic level, a solid state quantum computer in silicon together with other high potential implementations." Although attempts to develop a quantum computer have met with limited success, the centre has substantial resources invested in advancing toward practical uses of quantum computing technology. The site provides a very good introduction to the principles and implications of quantum computing, as well as details about various research projects underway at the Australian universities. Links to conference and journal papers produced by members of the centre, many from 2003, are also provided.
Traditional laboratory diffusion experiments in rock material are time consuming, and quite small samples are generally used. Electrical conductivity measurements, on the other hand, provide a fast means for examining transport properties in rock and allow measurements on larger samples as well. Laboratory measurements using electrical conductivity give results that compare well to those from traditional diffusion experiments. The measurement of the electrical resistivity in the rock surrounding a borehole is a standard method for the detection of water conducting fractures. If these data could be correlated to matrix diffusion properties, in-situ diffusion data from large areas could be obtained. This would be valuable because it would make it possible to obtain data very early in future investigations of potentially suitable sites for a repository. This study compares laboratory electrical ...
The purpose of this report is to advise managers on the status of Year 2000 readiness at the Laboratory and provide a summary of critical issues to be addressed in order to ensure that the Year 2000 date rollover will not disrupt Laboratory Operations. The Laboratory`s Year 2000 council members are in the first phase of Year 2000 plans: gathering data and assessing the status of their divisions or programs. This first snapshot of the Laboratory Year 2000 readiness assessment is expected to grow and change over time as more refined assessments, plans, and schedules are developed and as more information becomes available. Here are findings to date: (1) Embedded systems` status not known. (2) Preliminary cost estimates for Year 2000 repairs, testing, and implementation are estimated to be at least $5.9 million, not including embedded systems. (3) The Laboratory is required to make ...
This paper presents an investigation into the feasibility and potential advantages of a small scale Miller cycle natural gas engine for applications such as domestic combined heat and power systems. The Miller cycle engine is compared to a standard Otto cycle engine using cycle analyses and multidimensional simulation, and basic engine design implications are discussed. It is found that the Miller cycle engine has a potential for improved fuel efficiency, but at the cost of a reduced power to weight ratio. A fuel efficiency advantage of 5{yields}10% compared to a standard Otto cycle engine appears possible, however it is stated that further investigations, in particular into the topic of engine friction, are required in order to validate the findings. (author)
This paper presents an investigation into the feasibility and potential advantages of a small scale Miller cycle natural gas engine for applications such as domestic combined heat and power systems. The Miller cycle engine is compared to a standard Otto cycle engine using cycle analyses and multidimensional simulation, and basic engine design implications are discussed. It is found that the Miller cycle engine has a potential for improved fuel efficiency, but at the cost of a reduced power to weight ratio. A fuel efficiency advantage of Formula Not Shown compared to a standard Otto cycle engine appears possible, however it is stated that further investigations, in particular into the topic of engine friction, are required in order to validate the findings.
The Nuclear Data Interface (NDI) code library and data formats are the standards for multigroup nuclear data at Los Alamos National Laboratory. NDI's analysis, design, implementation, testing, integration, and maintenance required a ten person-year and ongoing effort by the Nuclear Data Team. Their efforts provide a unique, contemporary experience in producing a standard component library. In reflection upon that experience at NDI's decennial, we have identified several factors critical to NDI's success: it addressed real problems with appropriate simplicity, it fully supported all users, it added extra value through the code to the raw nuclear data, and its team went the distance from analysis through maintenance. In this report we review these critical success factors and discuss their implications for future standardization projects.
A microcosm laboratory experiment was conducted to determine the impact of biological reworking by the ragworm Nereis diversicolor on the redistribution of particle-bound radionuclides deposited at the sediment-water interface. Over the course of the 40-day experiment, as much as 35% of a 137Cs-labelled particulate tracer deposited on the sediment surface was redistributed to depths of up to 11 cm by the polychaete. Three different reworking models were employed to model the profiles and quantify the biodiffusion and biotransport coefficients: a gallery-diffuser model, a continuous sub-surface egestion model and a biodiffusion model. Although the biodiffusion coefficients obtained for each model were quite similar, the continuous sub-surface egestion model provided the best fit to the data...
Cell surface glycosaminoglycans play important roles in cell adhesion and viral entry. Laboratory strains of two alphaviruses, Sindbis and Semliki Forest virus, have been shown to utilize heparan sulfate as an attachment receptor, whereas Ross River virus (RRV) does not significantly interact with it. However, a single amino acid substitution at residue 218 in the RRV E2 glycoprotein adapts the virus to heparan sulfate binding and expands the host range of the virus into chicken embryo fibroblasts. Structures of the RRV mutant, E2 N218R, and its complex with heparin were determined through the use of electron cryo-microscopy and image reconstruction methods. Heparin was found to bind at the distal end of the RRV spikes, in a region of the E2 glycoprotein that has been previously implicated in cell-receptor recognition and antibody binding.
For 170 years, scientists have attempted to explain why consistent temporal patterns of death are observed among individuals within populations. Historical efforts to identify a {open_quotes}law of mortality{close_quotes} from these patterns ended in 1935 when it was declared that such a law did not exist. These empirical tests for a law of mortality were constructed using mortality curves based on all causes of death. We predicted that patterns of mortality consistent with the historical concept of a law would be revealed if mortality curves for species were constructed using only senescent causes of death. Using data on senescent mortality for laboratory animals and humans, we demonstrate that patterns of mortality overlap when compared on a biologically comparable time scale. These results are consistent with the existence of a law of mortality following sexual maturity as asserted by Benjamin Gompertz and Raymond Pearl. The societal, medical, and research ...
for 170 years, scientists have attempted to explain why consistent temporal patterns of death are observed among individuals within populations. Historical efforts to identify a `law of mortality` from these patterns ended in 1935 when it was declared that such a law did not exist. These empirical tests for a law of mortality were constructed using mortality curves based on all causes of death. We predicted patterns of mortality consistent with the historical concept of a law would be revealed if mortality curves for species were constructed using only senescent causes of death. Using data on senescent mortality for laboratory animals and humans, we demonstrate patterns of mortality overlap when compared on a biologically comparable time scale. The results are consistent with the existence of a law of mortality following sexual maturity. The societal, medical, and research implications of such a law are discussed.
A particle-laden turbulent reacting flow model is described and applied to in-furnace, dry SO_2 control in boilers. Sulfur capture by calcium-based sorbents is represented by a shrinking core model which accounts for surface areas loss and product layer diffusion. Sorbent particle trajectories and dispersion are followed with cloud statistics in a Lagrangian framework. The turbulent fluid mechanics and chemical reactions are coupled, and solutions obtained for mean and fluctuating velocity, composition, and particle position. Comparisons are made with data from an US EPA laboratory reactor. Practical implications for SO_2 control are examined including the effects of jet velocity, sorbent injection location, boiler load and thermal profiles.
The Arnowitt-Deser-Misner canonical formulation of general relativity is extended to the covariant brane-world theory in arbitrary dimensions. The exclusive probing of the extra dimensions makes a substantial difference, allowing for the construction of a non-constrained canonical theory. The quantum states of the brane-world geometry are defined by the Tomonaga-Schwinger equation, whose integrability conditions are determined by the classical perturbations of submanifolds contained in the Nash's differentiable embedding theorem. In principle, quantum brane-world theory can be tested by current experiments in astrophysics and by near future laboratory experiments at Tev energy. The implications to the black-hole information loss problem, to the accelerating cosmology, and to a quantum mathematical theory of four-sub manifolds are briefly commented.
This report is to present the progress made on the project ''Establishment of an Environmental Control Technology Laboratory (ECTL) with a Circulating Fluidized-Bed Combustion (CFBC) System'' during the period January 1, 2005 through March 31, 2005. The following tasks have been completed. First, the renovation of the new Combustion Laboratory is nearly complete, and the construction of the Circulating Fluidized-Bed (CFB) Combustor Building is in the final stages. Second, the fabrication and manufacture of the CFBC Facility is being discussed with a potential contractor. Discussions with potential contactor regarding the availability of materials and current machining capabilities have resulted in the modification of the original designs. The selection of the fabrication contractor for the CFBC Facility is expected during the next quarter. Third, co-firing experiments ...
Lawrence Livermore National Laboratory (LLNL) is implementing an Internet-based process pilot called `Zephyr` to streamline engineering and commerce using the Internet. Major benefits have accrued by using Zephyr in facilitating industrial collaboration, speeding the engineering development cycle, reducing procurement time, and lowering overall costs. Programs at LLNL are potentializing the efficiencies introduced since implementing Zephyr. Zephyr`s pilot functionality is undergoing full integration with Business Systems, Finance, and Vendors to support major programs at the Laboratory.
Laboratory studies have been carried out to determine the toxicity of methiocarb pellets to wild trapped wood mice in order to provide some background data prior to any further evaluation of hazard in the field. In this study, wood mice were exposed to dry and to dampened methiocarb pellets in order to reproduce field trial application conditions. Field observations of methiocarb pellets indicate that the physical character changes under dry and wet weather conditions. This may affect their relative attractiveness and potential toxicity to wood mice. The laboratory assessment of exposed wood mice included measurement of brain esterase activities, methiocarb residues in selected mouse tissue, carcasses, and histological evaluation of kidney, liver and lungs.
The United States Department of Energy (U.S. DOE) has recently implemented a series of strategic initiatives to address long-term radiological surveillance needs at former U.S. nuclear test sites in the Marshall Islands. The plan is to engage local atoll communities in developing shared responsibilities for implementing radiation protection monitoring programs for resettled and resettling populations in the northern Marshall Islands. Using the pooled resources of the U.S. DOE and local atoll governments, individual radiological surveillance programs have been developed in whole body counting and plutonium urinalysis in order to accurately assess radiation doses resulting from the ingestion and uptake of fallout radionuclides contained in locally grown foods. Permanent whole body counting facilities have been established at three separate locations in the Marshall Islands including Rongelap Atoll (Figure 1). These facilities are operated and maintained by Marshallese technicians with ...
This paper explores the potentialimplications of climate change for the use and management of water resources in Britain. It is based on a review of simulations of changes in river flows, groundwater recharge and river water quality. These simulations imply, under feasible climate change scenarios, that annual, winter and summer runoff will decrease in southern Britain, groundwater recharge will be reduced and that water quality - as characterised by nitrate concentrations and dissolved oxygen contents - will deteriorate. In northern Britain, river flows are likely to increase throughout the year, particularly in winter. Climate change may lead to increased demands for water, over and above that increase which is forecast for non-climatic reasons, primarily due to increased use for garden watering. These increased pressures on the water resource base will impact not only upon the reliability of water supplies, but also upon navigation, aquatic ...
Stem cell research has important implications for medicine. The source of stem cells influences their therapeutic potential, with stem cells derived from early-stage embryos remaining the most versatile. Somatic cell nuclear transfer (SCNT), a source of embryonic stem cells, allows for understandings about disease development and, more importantly, the ability to yield embryonic stem cell lines that are genetically matched to the somatic cell donor. However, SCNT requires women to donate eggs, which involves injection of ovulation-inducing hormones and egg retrieval through laparoscopy or transvaginal needle aspiration. Risks from this procedure are fiercely debated, most notably risk of ovarian hyperstimulation syndrome (OHSS). This review examines risk of OHSS resulting from oocyte donation. We conclude that risk posed by OHSS in egg donation is not significant enough to warrant undue concern, and much of this can be eliminated when proper ...
The DOE-Idaho Operations Office (DOE-ID) has prepared an environmental assessment (EA) on the replacement of the Idaho National Engineering Laboratory Health Physics Instrumentation Laboratory at the Idaho National Engineering Laboratory (INEL). The purpose of this project is to replace the existing Health Physics Instrumentation Laboratory (HPIL) with a new facility to provide a safe environment for maintaining and calibrating radiation detection instruments used at the Idaho National Engineering Laboratory. The existing HPIL facility provides portable health physics monitoring instrumentation and direct reading dosimetry procurement, maintenance and calibration of radiation detection instruments, and research and development support-services to the INEL and others. However, the existing facility was not originally designed for laboratory activities and does ...
The effect of uniaxial tensile stress on intergranular corrosion (IGC) of AA2024-T3 was studied using the foil penetration technique. Standard ASTM G49 fixed-displacement jigs were modified to allow the use of sheet samples, which were then attached to an electrochemical cell as in the foil penetration setup. The time for IGC to penetrate samples of varying thickness was monitored. This method provides a new approach to bridge the gap between IGC and intergranular stress corrosion cracking (IGSCC). Samples with various orientations relative to the rolling direction were studied in 1.0 M NaCl at controlled anodic potentials. Potentiodynamic polarization measurements indicated that the two breakdown potentials typically observed for AA2024-T3 were lower for stressed samples than for unstressed samples, and the current at a given potential was higher. The penetration rate depended on potential and was ...
Experimental and evaluated integral parameters derived from nuclear plus interference differential elastic scattering cross sections are presented for all projectile/target combinations of the particles p, d, t, /sup 3/He, and ..cap alpha... The data include reaction rates, average fractional energy losses per collision and per unit path length, and average laboratory scattering cosines. The resulting parameters are of potential use in analysis of charged-particle transport.
Recent investigations have identified elevated concentrations of polychlorinated dibenzo-p-dioxins (dioxins) in marine sediments and wildlife of Queensland, Australia. While it has been demonstrated that the contamination is widespread and predominantly land-based, limited information exists on the pathways and fate of these compounds within the near-shore marine system. This environment supports unique and threatened species including green sea turtles (Chelonia mydas). Adult green turtles are predominantly herbivorous, feeding on seagrass and algae. Apart from initial migration to feeding grounds (at {proportional_to}10 years of age) and intermittent migrations to breeding grounds (at {proportional_to}30-50 years and thereafter), green turtles remain and feed within relatively small home ranges. Long life-span (50 years or more), near-shore feeding grounds and highly specialized food requirements render green turtles potentially vulnerable to contaminant ...
The energy-versus-volume curve of the spin-density wave (SDW) in body-centred-cubic Cr is calculated with the density functional theory/full-potential linearized augmented plane wave (DFT/FLAPW) method using the generalized gradient approximation (GGA). The predicted ground state is not the SDW, in contrast to an earlier FLAPW calculation. A conjecture is formulated that the widely varying results of the local density approximation (LDA) and GGA - and of different solution methods - can be scaled by the size of the calculated moment. As a consequence, experimentally relevant properties of the SDW can be calculated by tuning the moment. The implications of these results for the ability of DFT to describe Cr are discussed. (author)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the elderly accounting for the vast majority of dementia. Recently, many studies have implicated the role of inflammatory response, especially neuroinflammatory response in the development and progression of AD. However, the underlying mechanism of how inflammatory response induces AD is unknown. Kynurenine pathway is a major route of the amino acid tryptophan catabolism, resulting in the production of nicotine adenine dinucleotide and other neuroactive intermediates: quinolinic acid (QA) and kynurenic acid (KA). QA exerts different toxic effects, including over-activation of N-methyl-d-aspartate (NMDA) receptor and excitotoxicity, synaptic dysfunction and neuronal death. On the other hand, KA is identified as the only...
Abstract Male infertility continues to be a clinical challenge of increasing significance. While male factors such as decreased semen quality are responsible for 25% of all infertility issues, the etiology of suboptimal semen quality is poorly understood. Many physiological, environmental, and genetic factors have been implicated, including oxidative stress. Oxidative stress is induced by reactive oxygen species (ROS), or free radicals, and although ROS are required for critical aspects of sperm function, excessive levels of ROS can negatively impact sperm quality. The origin of ROS generation, and the etiologies of increased ROS in men with suboptimal sperm quality have only recently been elucidated, offering multiple targets for potential therapy. Here, we present a critical review of th...
Using databases derived from the pattern recognition approach, the paper presents a methodology for utilizing fuzzy models to enhance the quality of decision-making using fuzzy-logic algorithms. Two multi-objective fuzzy-logic control algorithms for controlling power system static/dynamic security are presented and analyzed. The first algorithm is based on the successive inferences of fuzzy implication rules for each individual objective, and the second algorithm is an application of the method of fuzzy linear programming. The paper discusses the properties, advantages and limitations of applying fuzzy decision-making logic in the pattern-recognition approach and concludes by highlighting potential areas for further development. (author)
Current studies in plants suggest that the content of the coenzyme NAD is variable and potentially important in determining cell fate. In cases that implicate NAD consumption, re-synthesis must occur to maintain dinucleotide pools. Despite information on the pathways involved in NAD synthesis in plants, the existence of a mitochondrial nicotinamide mononucleotide adenylyltransferase (NMNAT) activity which catalyses NAD synthesis from nicotinamide mononucleotide (NMN) and ATP has not been reported. To verify the latter assumed pathway, experiments with purified and bioenergetically active mitochondria prepared from tubers of Jerusalem artichoke (Helianthus tuberosus L.) were performed. To determine whether NAD biosynthesis might occur, NMN was added to Jerusalem artichoke mitochondria (JAM)...
The dynamic response of cylindrical and ring-shaped YBaCuO bulk parts to pulsed magnetic fields is calculated by using small sets of finite elements. Some comparisons with experimental results are provided, and they give confidence in the modelling of the superconducting properties. Transient magnetizations as a function of time and space as well as shapes and absolute values of trapped magnetic flux profiles are presented. The influence of the sample geometry is investigated for different millisecond pulsed magnetization processes. Results are reported for different radial thicknesses and heights, different pulse durations, peak magnetic fields and pulse sequences with and without stepwise cooling. Comparisons concerning the achievable trapped magnetic field and flux are made, and implications for the use of high-temperature superconductor bulk parts as cryo-permanent magnets in potential applications like electric machinery are discussed.
Mathematics education reform emphasises the need to move away from transmission models of teaching to discursive classroom practices in which students negotiate and justify solutions to problems. This shift has potential, but not inevitable, implications for students' mathematical identities with respect to their sense of ownership and participation in mathematics as a creative activity, and is particularly pertinent in the UK context where ability grouping is prevalent. This paper presents an analysis of 13-15-year-old British pupils' accounts of learning and doing mathematics, and shows that the pedagogic practices of ability grouping do indeed play a major part in the development of participatory identities for some pupils but not for others. The data also show that learning is more tha...
This report reviews coal conversion processes which may be introduced in Canada within the next decade if interest in alternate energy technologies continues. A detailed review was conducted on coal liquefaction and gasification projects worldwide including information on individual proprietors, process technologies used, their present status and available environmental data. Further assessment of emissions and wastes emanating from commercial-scale plants was used to determine significant or potentially significant wastestreams connected to the various technologies, particularly wastewater discharges. Emphasis was placed on those technologies that are close to commercialization in Canada, i.e. SASOL II-type liquefaction facility at Hat Creek. Available information on wastewater treatment/reuse is also included in this report.
Fyn is a Src-family tyrosine kinase that affects long term potentiation (LTP), synapse formation, and learning and memory. Fyn is also implicated in dendritic spine formation both in vitro and in vivo. However, whether Fyn's regulation of dendritic spine formation is brain-region specific and age-dependent is unknown. In the present study, we systematically examined whether Fyn altered dendritic spine density and morphology in the cortex and hippocampus and if these effects were age-dependent. We found that Fyn knockout mice trended toward a decrease in dendritic spine density in cortical layers II/III, but not in the hippocampus, at 1month of age. Additionally, Fyn knockout mice had significantly decreased dendritic spine density in both the cortex and hippocampus at 3months and 1year, an...
This article provides a reconsideration of the intellectual altercation between John Dewey and Lewis Mumford in the 1920s, and a sketch of some educational implications that follow this reconsideration. Although past scholarship has tended to focus on ways in which the altercation obscured similarities in their thought, we consider whether important differences were also obscured, particularly regarding their outlook on science and technology, their potential place in society, and their ideas about the best means to positive social change. We also consider how these differences might play out in philosophy of education/educational practice, concluding that Mumford's commitment to regionalism can augment Dewey's philosophical vision while also helping deal with pressing contemporary social ...
Using a case-study, inductive, narrative approach, this article explores the history, drivers, benefits, and barriers to the Bakun Hydroelectric Project in East Malaysia. Situated on the island of Borneo, Bakun Dam is a 204m high concrete face, rock filled dam on the Balui River in the Upper Rajang Basin in the rainforests of Sarawak. Bakun Dam and its affiliated infrastructure could be the single largest and most expensive energy project ever undertaken in Southeast Asia. Based on data collected through site visits, original field research in Sarawak, and more than 80 research interviews, the article begins by teasing out the complex history and drivers behind the Bakun project before identifying a set of potential social, political, and economic benefits the project could deliver. It the...
Gamma-aminobutyric acid type A receptor-associated protein (GABARAP) belongs to a family of small ubiquitin-like adaptor proteins implicated in intracellular vesicle trafficking and autophagy. We have used diffusion-ordered nuclear magnetic resonance spectroscopy to study the temperature and concentration dependence of the diffusion properties of GABARAP. Our data suggest the presence of distinct conformational states and provide support for self-association of GABARAP molecules. Assuming a monomer-dimer equilibrium, a temperature-dependent dissociation constant could be derived. Based on a temperature series of {sup 1}H{sup 15}N heteronuclear single quantum coherence nuclear magnetic resonance spectra, we propose residues potentially involved in GABARAP self-interaction. The possible biological significance of these observations is discussed with respect to alternative scenarios of oligomerization.
The successful development of coal-fired combined cycle power generation systems require that all component parts are manufactured from appropriate materials and that these materials give predictable in-service performance. High temperature corrosion resulting from coal-derived particulates, deposition and gaseous species, is potentially life limiting for many components in these systems. Realistic laboratory test methods are outlined for gasifier and gas turbine environments and these have been combined with a materials assessment method based on accurate dimensional metrology. Such tests have allowed the production of models of materials performance as well as accurate comparisons between laboratory and plant derived data. These initial models predict the performance of materials well in the gas turbine environment, but tend to under-predict the damage observed in real gasifier environments. The differences found between ...
An estimate of the tritium dose to the public in the vicinity of the heavy water research reactor facility at AECL-Chalk River Laboratories, Ontario, Canada, has largely been accomplished from analyses on regularly-collected samples of air, precipitation, drinking water and foodstuffs (pasture, fruit, vegetables and milk) and environmental dose models. To increase the confidence with which public doses are calculated, tritium doses were estimated directly from the ratio of tritiated species in urine samples from members of the general public. Single cumulative 24 h urine samples from a few adults living in the vicinity of the heavy-water research reactor facility at Chalk River Laboratories, Canada were collected and analysed for tritiated water and organically bound tritium. The participants were from Ottawa (200 km east), Deep River (10 km west) and Chalk River Laboratories. Tritiated water concentrations in urine ranged ...
The Agency for Toxic Substances and Disease Registry (ATSDR) is a public health agency with responsibility for assessing the public health implications associated with uncontrolled releases of hazardous...Full Text Available
Studies have shown that Canada's national parks are vulnerable to the impacts of climate change. A wide range of biophysical climate change impacts could affect the integrity of conservation lands in each region of Canada. This report examines the potential impact of climate change on landscape alterations and vegetation distribution in Canada's wide network of conservation lands. It also presents several ways to integrate climate change into existing conservation policy and adaptation strategies. Canada's conservation lands include provincial parks, migratory bird sanctuaries, national wildlife areas and wildlife protected areas. This is the first study to examine biome changes by applying an equilibrium Global Vegetation Model (GVM) to Canada's network of national park systems. Some of the policy and planning challenges posed by changes in landscape level vegetation were also addressed. The report indicates that in terms of ...
The Executive Director for Operations (EDO) in establishing the Piping Review Committee concurred in its overall scope that included an evaluation of the potential for pipe breaks. The Pipe Break Task Group has responded to this directive. This report summarizes a review of regulatory documents and contains the Task Group's recommendations for application of the leak-before-break (LBB) approach to the NRC licensing process. The LBB approach means the application of fracture mechanics technology to demonstrate that high energy fluid piping is very unlikely to experience double-ended ruptures or their equivalent as longitudinal or diagonal splits. The Task Group's reommendations and discussion are founded on current and ongoing NRC staff actions as presented in Section 3.0 of this report. Additional more detailed comments and discussion are presented in Section 5.0 and in Appendices A and B. The obvious issues are the reexamination of the large pipe ...
The thermal regime immediately downstream from bottom release reservoirs is often characterized by reduced diel and seasonal (winter warm/summer cool) conditions. These unusual thermal patterns have often been implicated as a primary factor underlying observed downstream changes in the species composition of aquatic macroinvertebrate communities. The potential mechanisms for selective elimination of benthic species by unusual thermal regimes has been reviewed. Although the effects of temperature on the rate and magnitude of larval growth and development has been included in the list of potential mechanisms, only recently have field studies below dams focused on this interrelationship. This study investigates the overall community structure as well as the seasonal pattern of larval growth and development for several univoltine species of insects in the Delaware River below or near the hypolimnetic discharge of the ...
A compartment model, including removal of organic matter in a forest ecosystem, is developed to describe matter cycling and net CO{sub 2} flux of the ecosystem especially of managed forests. The model consists of five carbon stocks: atmosphere, foliage, woody matter, underground matter, and dead organic matter in the soil. Employing appropriate values of ecophysiological parameters in the model and simulation of man-made sugi (Cryptomeria japonica D. Don) plantation forests shows that these forests have high growth potential with a maximum total phytomass of over 750 t ha{sup -1} in dry matter basis. When the typical pattern of thinning regime for sugi plantation forests in Japan is applied to the present model, the simulated forest biomass developments compare well with mensuration data from various forestry sites. The CO{sub 2} balance between the sugi forest ecosystem and the atmosphere reveals a net CO{sub 2} fixation of 49.38 million ton CO{sub 2} year{sup -1} ...
Purpose: To use the theory of planned behavior (TPB) as a theoretical framework to explore in depth the range of beliefs held by consumers about internet shopping in general and internet grocery shopping in particular. Design/methodology/approach: Seven focus group interviews, four in the United Kingdom and three in Denmark, were conducted among consumers with different degrees of experience with internet grocery shopping. This diversification of respondents was chosen to capture a broad range of the consumer beliefs that predict intentions to buy groceries online or not. The TPB framework was used to construct the interview guide that was followed in all focus groups. Findings: An unexpected result of the explorative study was that the seven groups consisting of more or less experienced internet shoppers differed only little in their pool of beliefs (outcome and control beliefs). Beliefs about internet grocery shopping, positive as well as negative, were remarkably congruent across ...
The new SUERC AMS Laboratory was described at AMS-9. Since then there have been technological developments, added and improved analysis capability, the formation of additional complementary groups, the purchase of another instrument, and many samples measured. Be, C, Al, Cl, Ca and I-AMS are established with measured species changing weekly. Full-terminal potential running is now routine and 5MV is proving sufficient for all species. Ion detection and evaluation has also been improved by the use of even thinner detector windows as necessary and a more powerful on-line data analysis system. Routine radiocarbon measurement is to 4permil reproducibility at middling current and graphite samples of as little as 100mg C can be accommodated. Even smaller samples can be measured as CO2 using He ca...
DOE installations possessing sufficient quantities of fissile material to potentially constitute a critical mass, such that the excessive exposure of personnel to radiation from a nuclear accident is possible, are required to provide nuclear accident dosimetry services. This document describes the personal nuclear accident dosimeter (PNAD) used by SNL and prescribes methodologies to initially screen, and to process PNAD results. In addition, this report describes PNAD dosimetry results obtained during the Nuclear Accident Dosimeter Intercomparison Study (NAD23), held during 12-16 June 1995, at Los Alamos National Laboratories. Biases for reported neutron doses ranged from -6% to +36% with an average bias of +12%.
As a US Department of Energy (DOE) laboratory, Sandia Laboratories is developing Darrieus vertical axis wind turbine (VAWT) technology with the objective of encouraging private industry to produce economically feasible, commercially marketable wind energy systems. The first full cycle of development is essentially complete, and resulting current technology designs have been evaluated for cost-effectiveness. Aerodynamic, structural, and system analyses capabilities have evolved during this cycle to support and evaluate the system designs. This report presents some of the more salient recent developments, first generation costs, current activities, and future plans. Potential design improvements identified in the first development cycle are presented along with their cost benefits.
Studies of asphalt emulsion sealants conducted by the Pacific Northwest Laboratory have demonstrated that the sealants are effective in containing radon and other potentially hazardous material within uranium tailings. The laboratory and field studies have further demonstrated that radon exhalation from uranium tailings piles can be reduced by greater than 99% to near background levels. Field tests at the tailings pile in Grand Junction, Colorado, confirmed that an 8-cm admix seal containing 22 wt% asphalt could be effectively applied with a cold-mix paver. Other techniques were successfully tested, including a soil stabilizer and a hot, rubberized asphalt seal that was applied with a distributor truck. After the seals were applied and compacted, overburden was applied over the seal to protect the seal from ultraviolet degradation.
Data which have been collected by Los Alamos National Laboratory waste management for the hydrologic characterization of the subsurface at the low level radioactive waste disposal facility, Area G, are reported and discussed briefly. The data includes Unsaturated Flow Apparatus measurements of the unsaturated conductivity in samples from borehole G-5. Analysis compares these values to the predictions from van Genuchten estimates, and the implications for transport and data matching are discussed, especially at the location of the Vapor Phase Notch (VPN). There, evaporation drives a significant vapor flux and the liquid flux cannot be measured accurately by the UFA device. Data also include hydrologic characterization of samples from borehole G-5, Area G surface soils, Los Alamos (Cerros de Rio) basalt, Tsankawi and Cerro-Toledo layers, the Vapor Phase Notch (VPN), and additional new samples from the uppermost tuff layer at Area G. Hydraulic ...
Traditionally, probabilistic risk analyses [PRA] of severe accidents in nuclear power plants have limited themselves to consideration of the set of initiating events occurring during full power operation. However, some analyses of accident initiators during low power, shutdown, and other modes of plant operation other than full power have been performed. These studies as well as the Chernobyl accident and recent operating experience at U.S. pressurized water reactors suggested that risks during low power and shutdown could be significant. As such, the analysis of the frequencies, consequences, and risks of these accidents was identified as one task in the Nuclear Regulatory Commission staff's study of the implications of the Chernobyl accident to U.S. commercial nuclear power plants. The surry PRA project is an ongoing high priority effort at BNL [Brookhaven National Laboratory] that is expected to continue for the next several years. As the ...
Differential elastic and inelastic neutron-scattering cross sections of elemental iron are measured from 4.5 to 10 MeV in increments of {approx}0.5 MeV. The measurements are made at >or{approx}40 scattering angles distributed between {approx}17 and 160 , with emphasis on elastic scattering and inelastic scattering due to the excitation of the yrast 2{sup +} state. The measured data is combined with earlier lower-energy results from this laboratory, with recent high-precision {approx}9.5-15 MeV results from the Physikalisch. Technische Bundesanstalt and with selected values from the literature to provide a detailed neutron-scattering data base extending from {approx}1.5 to 26 MeV. This data is interpreted in the context of spherical-optical and coupled-channels (vibrational and rotational) models, and the physical implications are discussed. Deformation, coupling, asymmetry and dispersive effects are explored. A good description of the ...
The authors will be conducting an integrated seismic experiment to image the structure of the crust and upper mantle of northern California immediately before and after passage of the Mendocino Triple Junction. The purpose of this representation is to describe the project to other scientists interested in geological and geophysical processes in this region and to solicit input relevant to detailed siting of the funded seismic profiles. The experiment encompasses two field seasons: onshore seismic refraction/wide angle reflection data acquisition along three long profiles scheduled for late summer, 1993; and MCS deep crustal seismic reflection data acquisition accompanied by simultaneous large aperture recording using both ocean bottom and onshore seismographs, tentatively scheduled for summer, 1994. This study represents a component of a long-term, multi-disciplinary effort on the part of many investigators to exploit this well defined system as an in-situ ...
Very soon a new generation of reactor and accelerator neutrino oscillation experiments - Double Chooz, Daya Bay, Reno and T2K - will seek for oscillation signals generated by the mixing parameter theta_13. The knowledge of this angle is a fundamental milestone to optimize further experiments aimed at detecting CP violation in the neutrino sector. Leptonic CP violation is a key phenomenon that has profound implications in particle physics and cosmology but it is clearly out of reach for the aforementioned experiments. Since late 90's, a world-wide activity is in progress to design facilities that can access CP violation in neutrino oscillation and perform high precision measurements of the lepton counterpart of the Cabibbo-Kobayashi-Maskawa matrix. In this paper the status of these studies will be summarized, focusing on the options that are best suited to exploit existing European facilities (firstly CERN and the INFN Gran Sasso Laboratories) ...
The LANL Environmental Restoration (ER) Program Office, established in October 1989, is faced with the challenge of assessing and cleaning up nearly 1,8000 potentially hazardous waste sites according to an aggressive corrective action schedule that the Environmental Protection Agency (EPA) mandated on May 23, 1990, in a Resource, Conservation, and Recovery Act (RCRA) Part B Permit. To maximize program efficiency, the ER Program Office will implement a unique management approach designed to maximize the use of laboratory technical expertise. The Installation Work Plan, which provides a blueprint for the program, has been submitted to EPA for review and approval. A work plan for characterization of Technical Area 21, an early plutonium processing facility, is also nearing completion. The feasibility of an expedited cleanup of the Laboratory's worst hazardous waste release has been modelled using a computer code ...
This document is intended to provide an overview of the workshop entitled 'The Coming Nuclear Renaissance for the Next Generation Safeguards Experts-Maximizing Benefits While Minimizing Proliferation Risks', conducted at Oak Ridge National Laboratory (ORNL) in partnership with the Y-12 National Security Complex (Y-12) and the Savannah River National Laboratory (SRNL). This document presents workshop objectives; lists the numerous participant universities and individuals, the nuclear nonproliferation lecture topics covered, and the facilities tours taken as part of the workshop; and discusses the university partnership sessions and proposed areas for collaboration between the universities and ORNL for 2009. Appendix A contains the agenda for the workshop; Appendix B lists the workshop attendees and presenters with contact information; Appendix C contains graphics of the evaluation form results and survey areas; and Appendix D ...
The Mixed Waste Landfill occupies 2.6 acres in the north-central portion of Technical Area 3 at Sandia National Laboratories, Albuquerque, New Mexico. The landfill accepted low-level radioactive and mixed waste from March 1959 to December 1988. This report represents the Corrective Measures Study that has been conducted for the Mixed Waste Landfill. The purpose of the study was to identify, develop, and evaluate corrective measures alternatives and recommend the corrective measure(s) to be taken at the site. Based upon detailed evaluation and risk assessment using guidance provided by the U.S. Environmental Protection Agency and the New Mexico Environment Department, the U.S. Department of Energy and Sandia National Laboratories recommend that a vegetative soil cover be deployed as the preferred corrective measure for the Mixed Waste Landfill. The cover would be of sufficient thickness to store precipitation, minimize infiltration and deep ...
The Hanford Cultural Resources Laboratory (HCRL) was established by the US Department of Energy Field Office, Richland (RL) in 1987 as part of Pacific Northwest Laboratory. The HCRL provides support for managing the archaeological, historical, and cultural resources of the Hanford Site, Washington, in a manner consistent with federal statutes and regulations. This report summarizes activities of the HCRL during fiscal year (FY) 1990. The HCRL responsibilities have been set forth in the Hanford Cultural Resources Management Plan (HCRMP) as a prioritized list of tasks. The task list guided cultural resources management activities during FY 1990 and is the outline for this report. In order, these tasks were to (1) conduct cultural resource reviews, (2) develop an archaeological resources protection plan, (3) monitor the condition of known archaeological sites, (4) plan a curation system for artifacts and records, (5) evaluate cultural resources ...
Los Alamos National Laboratory is subject to annual emissions-reporting requirements for regulated air contaminants under Title 20 of the New Mexico Administrative Code, Chapter 2, Part 73 (20.2.73 NMAC), Notice of Intent and Emissions Inventory Requirements. The applicability of the requirements is based on the Laboratory's potential to emit 100 tons per year of suspended particulate matter, nitrogen oxides, carbon monoxide, sulfur oxides, or volatile organic compounds. For calendar year 2001, the Technical Area 3 steam plant was the primary source of criteria air pollutants from the Laboratory, while research and development activities were the primary source of volatile organic compounds. Emissions of beryllium and aluminum were reported for activities permitted under 20.2.72 NMAC. Hazardous air pollutant emissions from chemical use for research and development activities were also reported.
In response to US Department of Energy directives, Argonne National Laboratory (ANL) has developed a waste minimization plan aimed at reducing the amount of wastes at this national research and development laboratory. Activities at ANL are primarily research- oriented and as such affect the amount and type of source reduction that can be achieved at this facility. The objective of ANL's waste minimization program is to cost-effectively reduce all types of wastes, including hazardous, mixed, radioactive, and nonhazardous wastes. The ANL Waste Minimization Plan uses a waste minimization audit as a systematic procedure to determine opportunities to reduce or eliminate waste. To facilitate these audits, a computerized bar-coding procedure is being implemented at ANL to track hazardous wastes from where they are generated to their ultimate disposal. This paper describes the development of the ANL Waste Minimization Plan and a pilot ...
US Department of Energy (DOE) facilities are required to be in full compliance with all federal and state regulations. In response to this requirement, the Oak Ridge National Laboratory (ORNL) has established a Remedial Action Program (RAP) to provide comprehensive management of areas where past and current research, development, and waste management activities have resulted in residual contamination of facilities or the environment. This report presents the RCRA Facility Assessment (RFA) required to meet the requirements of RCRA Section 3004(u). Included in the RFA are (1) a listing of all sites identified at ORNL that could be considered sources of releases or potential releases; (2) background information on each of these sites, including location, type, size, period of operation, current operational status, and information on observed or potential releases (as required in Section II.A.1 of the RCRA permit); (3) ...
Newly commercialized Fourier transform Raman spectroscopic instrumentation provides a simpler alternative for vibrational spectroscopic analysis. Instrument vendors currently design for laboratory use, but there are many potential process applications of these stable, easy to use instruments. Raman spectroscopy is highly suited to analysis of aqueous samples. Near infrared excitation minimized fluorescence interference and allows for remote operation via fiber optic probes. The Department of Energy has funded research at the Measurement and Control Center to establish the utility of this method for on-line composition analysis in distillation columns. Laboratory evaluation and instrument employs an air-cooled laser and a thermoelectrically cooled detector. The device is mounted on a three by foot cart for convenient location in control rooms. Current fiber optic extension cables allow for analysis in a cell thirty five ...
Laboratory experiments were conducted to simulate the transfer of acidic THOREX waste from Tank 8D-4 into the alkaline PUREX waste in Tank 8D-2 at West Valley. The purpose of the experiments was to explore means of minimizing the production of nitric oxide (NO) gas during mixing of the two wastes and to assess the potential for the gas to further react in the vapor space possibly leading to enhanced corrosion of the tank walls. Forty one THOREX/PUREX mixing tests were conducted to explore the effects of stirring rate, pH, THOREX addition rate, THOREX or PUREX dilution, and temperature. The two most important criteria for minimizing NO production were to maintain some degree of agitation and the keep the pH in the PUREX high, preferably >12. Steel corrosion tests were performed in the presence of low partial pressures of NO{sub 2} and liquid water or water vapor. The NO{sub 2} (from oxidation of NO in the vapor space) concentrations were ...
Carbon steel is frequently used to construct concentrated sulphuric acid storage tanks. This paper discussed the corrosion performance of carbon steel tanks and outlined the underlying mechanisms responsible for major corrosion modes. Analyses of hydrogen grooving and dilute acid corrosion failure mechanisms were presented. Recent corrosion-induced leak failures were also discussed. The use of anodic protection and organic coatings as a corrosion control measure was also evaluated. The results of laboratory studies that were conducted to understand corrosion-induced failures showed that carbon steel electrodes exhibited transpassive corrosion at relatively high anodic potentials, while stainless steel electrodes exhibited transpassive corrosion at anodic potentials less than 1 V. It was concluded that corrosion-induced leaks can be prevented by using anodic protection and baked phenolic coating technologies. 23 refs., 9 ...
The USAF Surgeon General approved pyridostigmine bromide (PB) pretreatment for flying personnel as of 21 March 1986. However, specific side effects resulting from taking PB during high sustained + G/sub z/ stress, altitude stress, and periods of potential spatial disorientation had not yet been fully investigated. The USAF school of Aerospace Medicine (UASFSAM), Crew Technology Division, was therefore tasked with this clinical research effort. For effective investigation of these potential problem areas, rapid and accurate methods have had to be established for determining the blood plasma PB levels and the resultant inhibition of acetylcholinesterase activity. The basic purpose of this report is to describe in detail the analytical techniques used at USAFSAM to support the clinical research programs involving the physiological and performance aspects of USAF aircrews taking PB.
Ozone plays a critical role in both the chemistry and radiation balance of the troposphere. Understanding the factors controlling tropospheric ozone levels is critical to our understanding of a variety of issues in global chemistry and climate change. Chlorine atoms have the potential to contribute significantly to the ozone balance in the free troposphere. They can react directly with ozone or alternately, with organics and may actually lead to the formation of ozone in the presence of sufficient NO. Reactions of alkali halides in sea salt particles are a potential source of atomic chlorine, hence reactions of these alkali halides, especially those producing precursors to atomic chlorine, are of great interest. Finally, the mechanisms, intermediates and products of the Cl-biogenic reactions are unknown; these could serve as unique markers of chlorine atom chemistry in the troposphere, and hence are important to define.
This Safety Analysis Report (SAR) is prepared in compliance with the requirements of DOE Order 5480.23, Nuclear Safety Analysis Reports, and has been written to the format and content guide of DOE-STD-3009-94 Preparation Guide for U. S. Department of Energy Nonreactor Nuclear Safety Analysis Reports. The Hot Cell Facility is a Hazard Category 2 nonreactor nuclear facility, and is operated by Sandia National Laboratories for the Department of Energy. This SAR provides a description of the HCF and its operations, an assessment of the hazards and potential accidents which may occur in the facility. The potential consequences and likelihood of these accidents are analyzed and described. Using the process and criteria described in DOE-STD-3009-94, safety-related structures, systems and components are identified, and the important safety functions of each SSC are described. Additionally, information which describes the safety ...
In this context, the bulk ratio of CH4/N2 is examined as a potential alternative geochemical parameter for the assessment of thermal maturity of natural gas and compared to other previously published data. Open-system non-isothermal pyrolysis of low-mature coal from the Manjiaer sag, Tarim basin, yielded generation curves for methane and nitrogen. Analysis of the change of vitrinite reflectance indicates a two-stage process of thermal maturation with increasing temperatures. The relationship between Ro and pyrolysis temperature could be expressed by the following equations: Stage I: Ro = 0.0014T + 0.109, r = 0.9931(Ro Ro = 0.0067T -1.5855, r = 0.9996 (Ro > 0.6%). A kinetic interpretation of the characteristics of nitrogen and methane generation in humic coal during laboratory pyrolysis ind...
The refractive index of novel organosilica (nano/micro)material is determined using two methods. The first method is based on analysis of optical extinction efficiency of organosilica beads versus wavelength, which is obtained by a standard laboratory spectrometer. The second method relies on the measurable trapping potential of these beads in the focused light beam (laser tweezers). Polystyrene beads were used to test these methods, and the determined dispersion curves of refractive index values have been found accurate. The refractive index of organosilica beads has been determined to range from 1.60-1.51 over the wavelength range of 300-1100 nm.
Growing competitiveness of alternative manufacturing routes requires cost minimization in the production of drop forged components. The authors analyse the potential of medium carbon, vanadium microalloyed steels for drop forging. Laboratory and industrial experiments have been carried out emphasizing deformation and temperature cycles, strain rates and dwell times showing a typical processing path, associated mechanical properties and corresponding microstructures. The steels the required levels of mechanical properties on cooling after forging, eliminating subsequent heat treatment. The machinability of V-microalloyed steels is also improved when compared with plain medium carbon steels. (author)
This report issued by the Energy Economics Group and the Laboratory for Energy Systems Analysis at the Paul Scherrer Institute (PSI) analyses current and future trends in the area of energy and mobility on a global, European level as well as with respect to the German-speaking countries Austria, Germany and Switzerland. In a first step, developments with regard to how mobility is achieved and the energy consumption involved are examined and the impact of business-as-usual trends on global carbon dioxide (CO2) emissions and future fuel consumption is discussed. In a second step, the paper outlines potential alternative futures in terms of energy and mobility. Finally, the paper derives and presents recommendations for policy-makers.
This report issued by the Energy Economics Group and the Laboratory for Energy Systems Analysis at the Paul Scherrer Institute (PSI) analyses current and future trends in the area of energy and mobility on a global, European level as well as with respect to the German-speaking countries Austria, Germany and Switzerland. In a first step, developments with regard to how mobility is achieved and the energy consumption involved are examined and the impact of business-as-usual trends on global carbon dioxide (CO2) emissions and future fuel consumption is discussed. In a second step, the paper outlines potential alternative futures in terms of energy and mobility. Finally, the paper derives and presents recommendations for policy-makers.
The geothermal well-cost model developed by Sandia National Laboratories is being used to analyze the sensitivity of well costs to improvements in geothermal drilling technology. Three interim results from this modeling effort are discussed. The sensitivity of well costs to bit parameters, rig parameters, and material costs; an analysis of the cost reduction potential of an advanced bit; and a consideration of breakeven costs for new cementing technology. All three results illustrate that the well-cost savings arising from any new technology will be highly site-dependent but that in specific wells the advances considered can result in significant cost reductions.
In the quest to understand the ultimate nature of WIMPs, we propose the use of a hybrid detection technique: cylinders filled with liquefied noble gasses, acting as targets, are immersed inside a tank of Gd-doped ultra-pure water that provides an active and efficient veto against neutrons. The evaluation of the background rejection capabilities and physics potential of this instrument have been carried out through a full GEANT4 simulation, assuming the detector will be located at the Canfranc underground laboratory (in the Spanish Pyrenees). Our results compare very favourably with existing or planned experiments in the field. This technique is scalable and will allow to reach target masses of few tonnes in the next future.
This paper describes a novel Fourier transform infrared (FTIR) spectroscopic method that can be used to rapidly screen soil samples from potentially hazardous waste sites. Samples are heated in a thermal desorption unit and the resultant vapors are collected and analyzed in a long-path gas cell mounted in a FTIR. Laboratory analysis of a soil sample by FTIR takes approximately 10 minutes. This method has been developed to identify and quantify microgram concentrations of explosives in soil samples and is directly applicable to the detection of selected volatile organics, semivolatile organics, and pesticides.
Lawrence Livermore National Laboratory's Engineering Directorate has two primary discretionary avenues for its investment in technologies: the Laboratory Directed Research and Development (LDRD) program and the ''Tech Base'' program. This volume summarizes progress on the projects funded for technology-base efforts in FY2004. The Engineering Technical Reports exemplify Engineering's more than 50-year history of researching and developing (LDRD), and reducing to practice (technology-base) the engineering technologies needed to support the Laboratory's missions. Engineering has been a partner in every major program and project at the Laboratory throughout its existence, and has prepared for this role with a skilled workforce and technical resources. This accomplishment is well summarized by Engineering's mission: ...
In neurodegenerative conditions such as Alzheimer's and prion disease it has been shown that host genetic background can have a significant effect on susceptibility. Indeed, human genome-wide association studies (GWAS) have implicated several candidate genes. Understanding such genetic susceptibility is relevant to risks of developing variant CJD (vCJD) in populations exposed to bovine spongiform encephalopathy (BSE) and understanding mechanisms of neurodegeneration. In mice, aspects of prion disease susceptibility can be modelled by examining the incubation period following experimental inoculation. Quantitative trait linkage studies have already identified multiple candidate genes; however, it is also possible to take an individual candidate gene approach. Rarb and Stmn2 were selected as candidates based on the known association with vCJD. Because of the increasing overlap described between prion and Alzheimer's diseases we also chose Clu, Picalm and Cr1, which ...
Presently, Nigeria is one of the fastest growing Telecom markets in the world. The country's teledensity increased from a mere 0.4 in 1999 to 10 in 2005 following the liberalization of the Telecom sector in 2001. More than 25 million new digital mobile lines have been connected by June 2006. Large quantities of mobile phones and accessories including secondhand and remanufactured products are being imported to meet the pent-up demand. This improvement in mobile telecom services resulted in the preference of mobile telecom services to fixed lines. Consequently, the contribution of fixed lines decreased from about 95% in year 2000 to less than 10% in March 2005. This phenomenal progress in information technology has resulted in the generation of large quantities of electronic waste (e-waste) in the country. Abandoned fixed line telephone sets estimated at 120,000 units are either disposed or stockpiled. Increasing quantities of waste mobile phones estimated at 8 million units by 2007, ...
Superconducting generators for high power applications have been of interest for a number of years. Superconducting generators using low temperature superconductors (LTS) have been manufactured to produce up to 20 MW of electrical power and have been configured in either synchronous alternators which have an AC output that may be subsequently rectified to produce DC and homopolar generators which produce low voltage DC. Typically these generators require scrupulous attention to vacuum integrity for cryogenic insulation at 4.2K and tend to be somewhat fragile because of extensive thermal and magnetic shields that are not required in conventional power generators. Recently, high purity aluminum composites have been developed for a high power AC generator that is cooled by cryogenic hydrogen at 21K. This aluminum generator is very compact and lightweight and is much more robust than a generator made with LTS because extensive thermal and magnetic shields are not required internally. The ...
The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter release and in synaptogenesis, suggesting a potential role in several neuropsychiatric diseases. The human SYN3 gene is located on chromosome 22q12-13, a candidate region implicated in previous linkage studies of schizophrenia. However, association studies of SYN3 and schizophrenia have produced inconsistent results. In this study, four SYN3 SNPs (rs133945 (-631 C>G), rs133946 (-196 G>A), rs9862 and rs1056484) were tested in three sets of totally 3759 samples that comprise 655 affected subjects and 626 controls in the Irish Case-Control Study of Schizophrenia (ICCSS), 1350 samples incorporating 273 pedigrees in the Irish Study of High Density Schizophrenia Families (ISHDSF), and 564 unrelated schizophrenia patients and 564 healthy individuals in a Chinese ...
Based on the view that major changes in the social and economic context in the United States require major policy changes related to early childhood education, this paper examines the factors supporting public policy changes and how advocates for change in early childhood education might incorporate effective strategies. The paper is presented in two parts. Part 1 reviews the research on state policy settings and the factors that tend to support policy change. This part focuses attention on the ways that state policymakers appear to learn from what is going on elsewhere and incorporate new ideas into their policy agendas. Several strategic implications for advocates of policy change are presented, such as brainstorming a list of potential obstacles to the introduction of a policy innovation or shaping the debate so the public will support change. Part 2 of the paper takes these general strategic implications and considers ...
This is the final report of a one-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). In an effort to address the problems of long term storage and nuclear waste minimization, zircon has been proposed as a host medium for plutonium and other actinides recovered from dismantled nuclear weapons. The objective of this work is to investigate the feasibility of large scale fabrication of Pu-bearing zircon. Since PuO_2 is thermodynamically less stable than ZrO_2, it is expected that the process parameters determined for synthesizing ZrSiO_4 (zircon) would be applicable to those for PuSiO_4 (Pu-zircon). Furthermore, since the foremost concern in plutonium processing is the potential for contamination release, this work emphasizes the development of process parameters, using zircon first, to anticipate potential material problems in the containment ...
Abstract in english Cytokines are molecules that were initially discovered in the immune system as mediators of communication between various types of immune cells. However, it soon became evident that cytokines exert profound effects on key functions of the central nervous system, such as food intake, fever, neuroendocrine regulation, long-term potentiation, and behavior. In the 80's and 90's our group and others discovered that the genes encoding various cytokines and their receptors are e (more) xpressed in vascular, glial, and neuronal structures of the adult brain. Most cytokines act through cell surface receptors that have one transmembrane domain and which transduce a signal through the JAK/STAT pathway. Of particular physiological and pathophysiological relevance is the fact that cytokines are potent regulators of hypothalamic neuropeptidergic systems that maintain neuroendocrine homeostasis and which regulate the body's response to stress. The mechanisms ...
In this study, the complete sequence of the mitochondrial DNA (mtDNA) of Atelura formicaria (Hexapoda: Zygentoma) is described. The molecule is 15.205 bp in length and it is the third complete mt genome sequenced from the Zygentoma. The genome organization conforms with the putative ancestral insect gene arrangement. All protein coding genes use standard initiation codons (methionine and isoleucine). The exception is nad4 that starts with GTG, a codon used for this purpose in other insect species. A peculiar strand skew bias is observed, given that the PCGs encoded on the J-strand contain more thymines than adenines and more cytosines than guanines. This trend in nucleotide composition has been observed also in the "firebrat" Thermobia domestica (Zygentoma, Lepismatidae), but differs from that of the majority of hexapod species, including Tricholepidion gertschi (Zygentoma, Lepidotrichidae), where adenines and cytosines outnumber thymines and guanines. The presence of structural ...
Geothermal energy pile foundations are an alternative energy source for heating and cooling needs. Utilising this source of energy has great potential due to the environmental, economic and social benefits. This paper looks at an extensive amount of literature on the technology behind the system including the overall process, primary considerations for each of the main components including latest developments as well as design implications such as the integration of ground energy systems into structural piles of buildings. Environmental considerations including performance-dependent parameters of the subsurface are described. Main parameters include thermal conductivity, thermal diffusivity, specific heat capacity and moisture content. Temperature and groundwater effects are also discussed and design considerations are provided. Mathematical models are available to aid in the design of these systems but there are various other issues and ...
The cell's cytoskeleton, providing the cell with structure and shape, consists of a complex array of structural proteins, including microtubules, microfilaments and intermediate filaments. Intermediate filaments play a crucial role in mechanotransduction and in providing mechanical stability to cells, in particular under large deformation. By utilizing molecular simulation, here we report a nanomechanical analysis of vimentin intermediate filament dimers, the basic building blocks of intermediate filaments. We describe a detailed analysis of the mechanical properties and associated deformation mechanisms, and find that mechanical stretch induces a transition from alpha-helices to beta-sheets, a phenomenon known as alpha-beta transition. A comparison of the Young's modulus predicted from simulation with experimental measurements is provided, and good agreement is found. We present an analysis of structural changes during deformation, domain unfolding patterns, rate dependence of the ...
TC inhibits protein synthesis in E. coli by interfering with aminoacyl-tRNA binding to the ribosomal A site, and there is strong evidence that such inhibition results from TC binding to a high affinity site on the 30S subunit. The SPORE approach has been used to define those 30S proteins that are potentially important for high affinity TC binding, measured as the (/sup 3/H)-TC co-sedimenting with the reconstitution particle through a sucrose density gradient. Reverse phase-HPLC has been used both to prepare ribosomal proteins and to analyze the protein content of reconstituted particles. The results obtained so far show that protein S7, as well as some proteins linked to S7 in the 30S assembly map, are important for TC binding, whereas other ribosomal proteins are not. These results are in very good accord with their earlier photoaffinity labeling studies that strongly implicated S7 as forming part of the TC binding site. Interestingly, protein ...
Understanding feedbacks between terrestrial and atmospheric systems is vital for predicting the consequences of global change, particularly in the rapidly changing Arctic. Fire is a key process in this context, but the consequences of altered fire regimes in tundra ecosystems are rarely considered, largely because tundra fires occur infrequently on the modern landscape. We present paleoecological data that indicate frequent tundra fires in northcentral Alaska between 14,000 and 10,000 years ago. Charcoal and pollen from lake sediments reveal that ancient birchdominated shrub tundra burned as often as modern boreal forests in the region, every 144 years on average (+/- 90 s.d.; n = 44). Although paleoclimate interpretations and data from modern tundra fires suggest that increased burning was aided by low effective moisture, vegetation cover clearly played a critical role in facilitating the paleo-fires by creating an abundance of fine fuels. These records suggest that greater fire ...
This thesis reports on the fabrication and test of a new gaseous detector with a very large number of readout channels. This detector is intended for measuring the tracks of charged particles with an unprecedented sensitivity to single electrons of almost 100 %. It combines a metal grid for signal amplification called the Micromegas with a pixel readout chip as signal collecting anode and is dubbed GridPix. GridPix is a potential candidate for a sub-detector at a future electron linear collider (ILC) foreseen to work in parallel with the LHC around 2020--2030. The tracking capability of GridPix is best exploited if the Micromegas is integrated on the pixel chip. This integrated grid is called InGrid and is precisely fabricated by wafer post-processing. The various steps of the fabrication process and the measurements of its gain, energy resolution and ion back-flow property are reported in this document. Studies of the response of the complete detector formed by an ...
Dynamic Flowgraph Methodology (DFM) is a methodological approach to modeling and analyzing the behavior of software-driven embedded systems for the purpose of reliability/safety assessment and verification. The methodology has two fundamental goals: (a) to identify how certain postulated events may occur in a system and (b) to identify an appropriate testing strategy based on an analysis of system functional behavior. To achieve these goals, the methodology employs a modeling framework in which system models are developed in terms of causal relationships between physical variables and temporal characteristics of the execution of software modules. These models are then analyzed to determine how a certain state (desirable or undesirable) can be reached. This is done by developing timed fault trees, which take the form of logical combinations of static trees relating system parameters at different points in time. The prime implicants (multistate analog of minimal cut ...
The health politics and policy communities are still struggling with the question of "what went wrong" in the 1993-94 health care reform effort. Here I identify which Americans were politically active and inactive during the health care reform debate to explore the role political participation may have had in determining the outcome of the debate. Using data from a national and California random-sample telephone surveys, and controlling for other demographic attributes, I found that those who engaged in political activity specifically related to health care reform were disproportionately more likely to be self-identified conservatives, less likely to favor an employer mandate plan, more likely to be fifty to sixty-four years old, more likely to be men, and more likely to have greater interest in and knowledge of the health care issue. Even in California, where a single-payer proposal was on the November ballot, self-identified liberals were no more likely to engage in political ...
In this study, adjoint sensitivity theory is developed for equations of two-dimensional steady-state flow in a confined aquifer. Both the primary flow equation and the adjoint sensitivity equation are solved using the Galerkin finite element method. The developed computer code is used to investigate the regional flow parameters of the Leadville Formation of the Paradox Basin in Utah and the Wolcamp carbonate/sandstone aquifer of the Palo Duro Basin in the Texas Panhandle. Two performance measures are evaluated, local heads and velocity in the vicinity of potential high-level nuclear waste repositories. The results illustrate the sensitivity of calculated local heads to the boundary conditions. Local velocity-related performance measures are more sensitive to hydraulic conductivities. The uncertainty in the performance measure is a function of the parameter sensitivity, parameter variance and the correlation between parameters. Given a parameter covariance matrix, ...
It is currently unclear if the potential for West Nile virus transmission by mosquito vectors in the eastern United States is related to landscape or climate factors or both. We compared abundance of vector species between urban and suburban neighborhoods of Henrico County, VA, in relation to the following factors: temperature, precipitation, canopy cover, building footprint, and proximity to drainage infrastructure. Mosquitoes were collected throughout the 2005, 2006, and 2007 seasons and tested for West Nile virus (WNV) in pools of 10-50. Test results of mosquito pools were compared to average site abundance from 37 sites in Henrico County, VA; abundance was then examined in relation to ecological variables. Urban infrastructure was positively correlated with the abundance of Culex pipiens L./Cx. restuans, and our findings implicate combined sewer overflow systems as large contributors to Culex vector populations. No measure of urbanization ...
High temperature thermochemistry of thoria-urania fuel for Advanced Heavy Water Reactor was investigated. Oxygen potential development within the matrix and distribution behaviors of the fission products (fps) in different phases were worked out with the help of thermodynamic and transport properties of the fps as well as fission generated oxygen and the detailed balance of the elements. Some of the necessary data for different properties were generated in this laboratory while others were taken from literatures. Noting the behavior of poor transports of gases and volatile species in the thoria rich fuel (thoria-3 mol% urania), the evaluation shows that the fuel will generally bear higher oxygen potential right from early stage of burnup, and Mo will play vital role to buffer the potential through the formation of its oxygen rich chemical states. The problems related to the poor transport and larger ...
A three-dimensional computational fluid dynamics (CFD) electrochemical model has been created to model high-temperature electrolysis stack performance and steam electrolysis in the Idaho National Laboratory (INL) Integrated Lab Scale (ILS) experiment. The model is made of 60 planar cells stacked on top of each other operated as Solid Oxide Electrolysis Cells (SOEC). Details of the model geometry are specific to a stack that was fabricated by Ceramatec, Inc. and tested at INL. Inlet and outlet plenum flow and distribution are considered. Mass, momentum, energy, and species conservation and transport are provided via the core features of the commercial CFD code FLUENT. A solid-oxide fuel cell (SOFC) model adds the electrochemical reactions and loss mechanisms and computation of the electric field throughout the cell. The FLUENT SOFC user defined subroutine was modified for this work to allow for operation in the SOEC mode. Model results provide detailed profiles of ...
After the introduction Chapter 2 presents details of the ecological-economic analysis based on the FAO/IIASA agro-ecological zones (AEZ) approach for evaluation of biophysical limitations and agricultural production potentials, and IIASA's Basic Linked System (BLS) for analyzing the world's food economy and trade system. The BLS is a global general equilibrium model system for analyzing agricultural policies and food system prospects in an international setting. BLS views national agricultural systems as embedded in national economies, which interact with each other through trade at the international level. The combination of AEZ and BLS provides an integrated ecological-economic framework for the assessment of the impact of climate change. We consider climate scenarios based on experiments with four General Circulation Models (GCM), and we assess the four basic socioeconomic development pathways and emission scenarios as formulated by the ...
The mouth is an obvious portal of entry to the body, and oral health reflects and influences general health and well being. Maternal oral health has significant implications for birth outcomes and infant...Full Text Available
A yellow-pigmented, gram-negative, gliding bacterium isolated from an industrial water spray air humidification system was implicated as a causative agent in several occurrences of lung disease with...Full Text Available
The 7 conference papers in Vol. 9 review the implications of environmental problems and discuss the consequences of pollution abatement measures, especially for the economics of energy conversion. The future developments of pollutant emissions are assessed.
"Correctional Health Care: Implications for Public Health Policy" is the first in a series of articles that examines the special health care needs of persons who are incarcerated in America's correctional...Full Text Available
Jurisdictional wetlands of the Argonne National Laboratory-East (ANL-E) site in DuPage County, Illinois, were delineated in the summer and autumn of 1993 in accordance with the 1987 US Army Corps of Engineers methodology. Potential wetland sites with an area greater than 500 m{sup 2} (0.05 ha [0.124 acre]) were identified for delineation on the basis of aerial photographs, the DuPage County soil survey, and reconnaissance-level field studies. To qualify as a jurisdictional wetland, an area had to support a predominance of hydrophytic vegetation as well as have hydric soil and wetland hydrology. Thirty-five individual jurisdictional wetlands were delineated at ANL-E, totaling 180,604 m{sup 2} (18.1 ha [44.6 acres]). These wetlands were digitized onto the ANL-E site map for use in project planning. Characteristics of each wetland are presented -- including size, dominant plant species and their indicator status, hydrologic characteristics ...
The program goals for the first quarter were to located and contact potential manufacturers of these components, evaluate their level of interest, and begin discussions of the type and design of the prototypes to be fabricated for their evaluation. Thoughtful discussion at this stage would result in fabricating prototypes which answer the greatest number of questions possible for a given manufacturer at the lowest cost to this program. In the present economy many manufacturing firms have almost no funds for testing and evaluating new materials. This places a greater burden on the data obtained from outside laboratories. In many cases this data will be used to make that first evaluation on MRCC`s (metal reinforced carbon composites) suitability for a given application and give firms the confidence to commit to a evaluation program. In Exhibit 1, which is attached to this report the authors have the first set of data from outside ...
The performance of a geologic repository for high-level nuclear waste will be influenced to a large degree by thermohydrologic phenomena created by the emplacement of heat-generating radioactive waste. The importance of these phenomena is manifest in that they can greatly affect the movement of moisture and the resulting transport of radionuclides from the repository. Thus, these phenomena must be well understood prior to a definitive assessment of a potential repository site. An investigation has been undertaken along three separate avenues of analysis: (i) laboratory experiments, (ii) mathematical models, and (iii) similitude analysis. A summary of accomplishments to date is as follows. (1) A review of the literature on the theory of heat and mass transfer in partially saturated porous medium. (2) A development of the governing conservation and constitutive equations. (3) A development of a dimensionless form of the governing equations. (4) A ...
The U.S. Department of Energy (DOE) is interested in developing tools and methods for potential U.S. use in designing and evaluating safeguards systems. For this goal several DOE National Laboratories are defining the characteristics of typical facilities of several size scales, and the safeguards measures and instrumentation that could be applied. Lawrence Livermore National Laboratory is providing systems modeling and analysis of facility and safeguards operations, diversion path generation, and safeguards system effectiveness. The constituent elements of diversion scenarios are structured using directed graphs (digraphs) and fault trees. Safeguards indicator probabilities are based on sampling statistics and/or measurement accuracies. Scenarios are ranked based on value and quantity of material removed and the estimated probability of non-detection. Significant scenarios, especially those involving timeliness or randomly ...
The purpose of this project was to investigate the origin of pressure fluctuations in fluidized bed systems. The study assessed the potential for using pressure fluctuations as an indicator of fluidized bed hydrodynamics in both laboratory scale cold-models and industrial scale boilers. Both bubbling fluidized beds and circulating fluidized beds were evaluated. Testing including both cold-flow models and laboratory and industrial-scale combustors operating at elevated temperatures. The study yielded several conclusions on the relationship of pressure fluctuations and hydrodynamic behavior in fluidized beds. The study revealed the importance of collecting sufficiently long data sets to capture low frequency (on the order of 1 Hz) pressure phenomena in fluidized beds. Past research has tended toward truncated data sets collected with high frequency response transducers, which miss much of the spectral structure of fluidized ...
The study investigated the luminescence behaviour of natural olivine to discuss the potential for Cenozoic (quaternary) dating. The UV-blue thermoluminescence (TL) glow curves of irradiated olivines have a resolved peak at 190 deg. C and other peaks at higher temperature at lower dose levels, and broad signals around 275-310 and 375-400 deg. C at higher dose levels. The UV-blue TL increases with additional laboratory dose to {approx}1.6kGy within a plateau temperature region, suggesting the possibility of dosimetry and Cenozoic dating. Both infrared stimulated luminescence (IRSL) and blue light stimulated luminescence (BLSL) were detected from laboratory-irradiated olivines although the BLSL was weaker than the IRSL. Furthermore, post-BL IRSL was detected but post-IR BLSL was not observed. Therefore, IR stimulation is recommended for optically stimulated luminescence measurements with natural olivine. The growth of the IRSL ...
Finite element method is one of the bases for numerical solutions to engineering problems. Complex engineering problems using finite element analysis typically imply excessively large computational time. Parallel supercomputers have the potential for significantly increasing calculation speeds in order to meet these computational requirements. This paper predicts parallel NIKE3D performance on the Kendall Square Research (KSR1) system. The first part of the prediction is based on the implementation of parallel Cholesky (U{sup T}DU) matrix decomposition algorithm through actual computations on the KSRI multiprocessor system, with 64 processors, at Oak Ridge National Laboratory. The other predictions are based on actual computations for parallel element matrix generation, parallel global stiffness matrix assembly, and parallel forward/backward substitution on the BBN TC2000 multiprocessor system at Lawrence Livermore National ...
This is the final report of a two-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). This project has examined the fundamental chemistry of plutonium that affects the integration of hydrothermal technology into nuclear materials processing operations. Chemical reactions in high temperature water allow new avenues for waste treatment and radionuclide separation.Successful implementation of hydrothermal technology offers the potential to effective treat many types of radioactive waste, reduce the storage hazards and disposal costs, and minimize the generation of secondary waste streams. The focus has been on the chemistry of plutonium(VI) in solution with carbonate since these are expected to be important species in the effluent from hydrothermal oxidation of Pu-containing organic wastes. The authors investigated the structure, solubility, and stability of the key ...
In an effort to develop cost-efficient techniques for remediating uranium contaminated groundwater at DOE Uranium Mill Tailing Remedial Action (UMTRA) sites nationwide, Sandia National Laboratories (SNL) deployed a pilot scale research project at an UMTRA site in Durango, CO. Implementation included design, construction, and subsequent monitoring of an in situ passive reactive barrier to remove Uranium from the tailings pile effluent. A reactive subsurface barrier is produced by emplacing a reactant material (in this experiment various forms of metallic iron) in the flow path of the contaminated groundwater. Conceptually the iron media reduces and/or adsorbs uranium in situ to acceptable regulatory levels. In addition, other metals such as Se, Mo, and As have been removed by the reductive/adsorptive process. The primary objective of the experiment was to eliminate the need for surface treatment of tailing pile effluent. Experimental design, and ...
Objectives- Investigate the potential for the use of enzymes to bring about improvements in the recycling of recovered waste paper sources~%~~%~- Optimise enzyme formulations and process conditions to maximise benefits. - Produce recovered fibre at lower energy and chemical costs than is currently achievable using 'classical' de-inking techniques.~%~~%~- Improve recycled fibre quality and~%~~%~- All of the above will allow a greater use of recovered paper resources, which would otherwise be diposed of by [continued...]DescriptionThe project proposes to carry out an initial literature review to update the consortium on the currently available publications relating to the use of enzymes in de-inking.. This will be followed by an intensive laboratory study in an upgraded facility which will allow enzyme formulations and mechanisms to be studied. This work will also eliminate the need for an ...
This patent describes an expert overseer for the operation and real-time management of a mass spectrometer and associated laboratory equipment. The overseer is a computer-based expert diagnostic system implemented on a computer separate from the dedicated computer used to control the mass spectrometer and produce the analysis results. An interface links the overseer to components of the mass spectrometer, components of the laboratory support system, and the dedicated control computer. Periodically, the overseer polls these devices and as well as itself. These data are fed into an expert portion of the system for real-time evaluation. A knowledge base used for the evaluation includes both heuristic rules and precise operation parameters. The overseer also compares current readings to a long-term database to detect any developing trends using a combination of statistical and heuristic rules to evaluate the results. The overseer has the capability ...
This patent describes an expert overseer for the operation and real-time management of a mass spectrometer and associated laboratory equipment. The overseer is a computer-based expert diagnostic system implemented on a computer separate from the dedicated computer used to control the mass spectrometer and produce the analysis results. An interface links the overseer to components of the mass spectrometer, components of the laboratory support system, and the dedicated control computer. Periodically, the overseer polls these devices and as well as itself. These data are fed into an expert portion of the system for real-time evaluation. A knowledge base used for the evaluation includes both heuristic rules and precise operation parameters. The overseer also compares current readings to a long-term database to detect any developing trends using a combination of statistical and heuristic rules to evaluate the results. The overseer has the capability ...
The newly developed techniques by the Hot Laboratory (JMTR HL) have provided for us the key information on behavior of specimens due to mechanical / physical / chemical / synergistic effects of radiation, stress and water for fission and fusion reactor environment. These techniques are focused on several topics as follows; (1) miniaturized specimen test for the development of fusion reactor materials, (2) slow strain rate tensile testing (SSRT) and crack propagation measuring tests for the study of Irradiation Assisted Stress Corrosion Cracking (IASCC) of core internals of LWR, (3) handling technique on specimens including tritium for the research and development of tritium breeders and neutron multiplier as fusion blanket materials, (4) joining method using the Tungsten Inert Gas (TIG) welding technique for re-assembling of capsule and re-fabrication of specimen and (5) nondestructive evaluation using ultrasonic wave and infrared thermography for the quantitative ...
Chemical-looping combustion (CLC), has previously been studied as a method for separating CO{sub 2} during combustion of gaseous fuels. In this project the possibility to apply this process for direct use of solid fuels has been investigated. The following has been accomplished: A 10 kW reactor system for CLC with solid fuels has been designed and built. Tests with solid fuel and metal oxid particles in a laboratory reactor show that it is possible to oxidize solid fuels with metal oxide particles in cyclic testing, thus giving proof of basic concept. They also show how the reaction rate is affected by temperature, steam concentration etc., and, most important of all, that the rates of reaction are realistic. Tests with metal oxide materials available at low costs have been successful. Chemical-looping combustion with solid fuels has a potential to achieve very low costs for separation of CO{sub 2}, below 10 Euro/ton CO{sub 2}. In summary the ...
Monitoring brine chemistry to determine the extent of potential adverse reactions was simplified by the development of a field brine test kit and a series of nomographs. Results of the kit analyses serve as input to the nomographs, which provide a graphic means of determining the scaling tendency (Saturation Index value) of a brine. Brines that do not tend to form scale may be corrosive. Saturation Index values have been correlated with various processes using data from geopressured wells in the Gulf Coast area. Control of scale in surface equipment of geopressured wells by chemical inhibitors has been successful. Downhole treatment with inhibitors to prevent scale formation in the production tubing is being investigated. Laboratory simulations indicate that an inhibitor squeeze treatment may be successful at the Gladys McCall No. 1 well. Inhibitor mixtures exhibit additive behavior at minimum concentration levels; however, behavior at maximum ...
This report summarizes the work that was completed in FY 1992 on the program {open_quotes}Technology Development for Concentrating Process Streams.{close_quotes} The purpose of this program is to evaluate and develop evaporator technology for concentrating radioactive waste and product streams such as those generated by the TRUEX process. Concentrating these streams and minimizing the volume of waste generated can significantly reduce disposal costs; however, equipment to concentrate the streams and recycle the decontaminated condensates must be installed. LICON, Inc., is developing an evaporator that shows a great deal of potential for this application. In this report, concepts that need to be incorporated into the design of an evaporator operated in a radioactive environment are discussed. These concepts include criticality safety, remote operation and maintenance, and materials of construction. Both solubility and vapor-liquid equilibrium data are needed to ...
Potential maximum radiation dose rates were calculated for the former Alba Craft Laboratory site in Oxford, Ohio, which was involved in machining of uranium metal in the 1950s for the U.S. atomic energy program. The site is not currently being used. The residual radioactive material guidelines (RESRAD) computer code, which implements the methodology described in the US Department of Energy`s (DOE`s) manual for establishing residual radioactive material guidelines, was sued in this evaluation. Three potential land use scenarios were considered for the former Alba Craft site; the scenarios vary with regard to the type of site use, time spent at the site by the exposed individual, and sources of food consumed. Scenario A (a possible land use scenario) assumed industrial use of the site; Scenario B (a likely future land use scenario) assumed residential use of the site; and Scenario C (a possible but unlikely land use scenario) ...
The proposed action is to recycle slightly activated copper that is currently stored in a warehouse leased by Lawrence Berkeley Laboratory (LBL) to a scrap metal dealer. Subsequent reutilization of the copper would be unrestricted. This document addresses the potential environmental effects of recycling and reutilizing the activated copper. In addition, the potential environmental effects of possible future uses by the dealer are addressed. Direct environmental effects from the proposed action are assessed, such as air emissions from reprocessing the activated copper, as well as indirect beneficial effects, such as averting air emissions that would result from mining and smelting an equivalent quantity of copper ore. Evaluation of the human health impacts of the proposed action focuses on the pertinent issues of radiological doses and protection of workers and the public. Five alternatives to the proposed action are ...
This report provides a user's manual for PROTOCOL, a comprehensive coupled kinetic/equilibrium computer program for analyzing the dissolution reactions of solids with aqueous solutions, specifically applied to the potential corrosion of vitrified nuclear waste by groundwater. The capabilities and available options are summarized as well as instructions for setting up and running problems. Also described in this report and included in the PROTOCOL software package are MASTER, a master file of species thermodynamic data, MANEQL, a preprocessor program and POSTP, a postprocessor. POSTP provides offline plotting using the CRAY-1 DISSPLA 9.0 graphics library. PROTOCOL is operational on the CDC-7600 and CRAY-1 computers at the Lawrence Livermore National Laboratory. 7 references, 10 figures, 2 tables.
Alloy 800 has been used for steam generator (SG) tubing for more than 30 years, primarily in CANDU reactors worldwide and in reactors in Germany. Extensive laboratory testing and in-service experience suggest that the Alloy 800 tubing has excellent resistance to corrosion-related degradation under appropriate operating conditions. In planning refurbishment of nuclear plants stations, a key concern is the longevity of existing SGs up to the 60-year lifetime of the refurbished plant. The paper reviews an existing methodology based on the concept of the improvement factor, and refines its estimation based on data specific to CANDU operating conditions. The paper presents a more advanced Bayesian probabilistic approach to estimate the degradation free lifetime distribution of Alloy 800 tubing, which is used to quantify the probability of degradation during the service life and to evaluate the impact of potential occurrences of degradation on ...
Alloy 800 has been used for steam generator (SG) tubing for more than 30 years, primarily in CANDU reactors worldwide and in reactors in Germany. Extensive laboratory testing and in-service experience suggest that the Alloy 800 tubing has excellent resistance to corrosion-related degradation under appropriate operating conditions. In planning refurbishment of nuclear plants stations, a key concern is the longevity of existing SGs up to the 60-year lifetime of the refurbished plant. The paper reviews an existing methodology based on the concept of the improvement factor, and refines its estimation based on data specific to CANDU operating conditions. The paper presents a more advanced Bayesian probabilistic approach to estimate the degradation free lifetime distribution of Alloy 800 tubing, which is used to quantify the probability of degradation during the service life and to evaluate the impact of potential occurrences of degradation on ...
Solar thermophotovoltaics (STPV) potentially have high system power efficiency together with other attractive attributes for both space and terrestrial applications. This paper presents a summary of work that has been conducted by NASA Lewis Research Center (LeRC) and McDonnell Douglas Aerospace (MDA). The paper discusses analytical modeling and subsystem testing, laboratory, and field testing that has been conducted. The features which make solar thermophotovoltaics attractive for both space and terrestrial applications are discussed. Based upon these investigations and the work of others, a conceptual design has been formulated, and an estimate of system performance is presented. This estimate indicates a solar thermophotovoltaics system can result in competitive energy costs for the utility electrical market applications and a high power-to-mass ratio for space power applications.
The Structural Aging (SAG) Program is carried out by the Oak Ridge National Laboratory (ORNL) under sponsorship of the United States Nuclear Regulatory Commission (USNRC). The Program has evolved from preliminary studies conducted to evaluate the long-term environmental challenges to light-water reactor safety-related concrete civil structures. An important conclusion of these studies was that a damage methodology, which can provide a quantitative measure of a concrete structure's durability with respect to potential future requirements, needs to be developed. Under the SAG Program, this issue is being addressed through: establishment of a structural materials information center, evaluation of structural component assessment and repair technologies, and development of a quantitative methodology for structural aging determinations. Progress to date of each of these activities is presented as well as future plans. 7 refs., 5 figs.
The Surry low power and shutdown probabilistic risk analysis (PRA) is an ongoing project at Brookhaven National Laboratory (BNL) to identify and quantify potential accident scenarios that may occur in a pressurized water reactor (PWR) during low power and shutdown. It was initiated as a result of various incidents and accidents that have occurred within the United States and overseas. The project involves review and evaluation of PWR experience at shutdown, identification of accident scenarios, determination of methods to mitigate the accidents, and performance a level 1 PRA. An evaluation of accident progression, source terms and consequences has also been initiated. The results will be used to address issues related to shutdown conditions. The objective of this paper is to provide a progress report on the project, and to present the approach used as well as the preliminary results of the ongoing and completed tasks.
Presented are the results from a laboratory test program conducted to identify and evaluate materials for converting hazardous geothermal residues to a non-hazardous and potentially usable form. Results indicate that the residues can be effectively incorporated, as a fine aggregate, into portland cement-based composites. Five geothermal residues obtained from sites in the Salton Sea area of California were evaluated. Three of these were classified as hazardous. After mixing with cement, the leach rates were all well below specified levels. Although structural-grade composites were produced, gradual reductions in properties with time up to 1 yr were noted. This indicates ongoing chemical reactions between the cement paste and the constituents of the residues. Further research is necessary before the composites could be considered for use in structural applications. 3 refs., 8 tabs.
The estimation of radiation dose to man from either external or internal exposure to radionuclides requires a knowledge of the energies and intensities of the atomic and nuclear radiations emitted during the radioactive decay process. The availability of evaluated decay data for the large number of radionuclides of interest is thus of fundamental importance for radiation dosimetry. This handbook contains a compilation of decay data for approximately 500 radionuclides. These data constitute an evaluated data file constructed for use in the radiological assessment activities of the Technology Assessments Section of the Health and Safety Research Division at Oak Ridge National Laboratory. The radionuclides selected for this handbook include those occurring naturally in the environment, those of potential importance in routine or accidental releases from the nuclear fuel cycle, those of current interest in nuclear medicine and fusion reactor ...
A new process engineering flowsheet reflecting an improved design of the LASL Bismuth Sulfate thermochemical cycle is presented. The design is based on laboratory data that indicate a lowered endothermic heat load for a partial decomposition of the solid bismuth sulfate. A small electrical energy demand should result from operation of the sulfur dioxide electrolytic step at lower acid concentration, in principle. The results of the flowsheeting analysis yield a thermal efficiency of 50% for the cycle when coupled to a conceptual fusion energy heat source at 1500/sup 0/K. A parametric analysis shows a slight drop in efficiency as the temperature of the heat source is decreased. The LASL Bismuth Sulfate thermochemical cycle appears to have potential as a means of producing hydrogen from high-temperature heat sources such as fusion, fission, and solar energy; it also appears to be competitive with alternative thermochemical cycles as well as with ...
Heavy Ion Collisions at RHIC and LHC energies are potentially an interesting laboratory for the study of QED. In these collisions, a Heavy Ion in one beam sees a highly Lorentz contracted electric field due to an oncoming beam particle. The Electric field reaches a maximum value of E {approx_equal} {gamma}{sub eff} {center_dot} Z {center_dot} e/b{sup 2}, where the apparent Lorentz factor, {gamma}{sub eff} = 2 {center_dot} {gamma}{sub beam}{sup 2} - 1. The collision may be viewed in terms of a flux of photons colliding with a stationary ion target using the equivalent photon approximation, originally introduced by Fermi in 1924. We show that the cross section for Inelastic Electromagnetic Interactions of Heavy Ions are both calculable and have been measured in the first RHIC running period.
Microbial enhanced oil recovery (MEOR) technology has advanced internationally since 1980 from a laboratory-based evaluation of microbial processes to field applications. In order to adequately support the decline in oil production in certain areas, research on cost-effective technologies such as microbial enhanced oil recovery processes must focus on both near-term and long-term applications. Many marginal wells are desperately in need of an inexpensive improved oil recovery technology today that can assist producers in order to prevent their abandonment. Microbial enhanced waterflooding technology has also been shown to be an economically feasible technology in the United States. Complementary environmental research and development will also be required to address any potential environmental impacts of microbial processes. In 1995 at this conference, the goal is to further document and promote microbial processes for improved oil recovery and ...
Magnetic refrigeration uses the temperature- and field-dependence of the entropy of some magnetic materials to accomplish cooling. Because of the intrinsically high efficiency of the magnetization and demagnetization process and because of the potential for excellent heat transfer between solids and fluids, magnetic refrigerators promise to have higher efficiency than existing gas-cycle refrigerators. Many ground-based and space-based applications could benefit significantly from the cost savings implied by higher efficiency. Other attributes of these devices are high reliability and low volume and mass per unit cooling power. The development of these refrigerators is underway at several places around the world, including the Los Alamos National Laboratory. The progress to date has been encouraging but some problems have been clearly identified. The arguments for high efficiency and the problems that will need to be solved to achieve this goal ...
Tests using reconstituted samples have been performed to assess the diffusive transport of 137Cs and 60Co through natural regolith materials from a region in South Australia being considered for a radioactive waste repository. A double diffusion cell apparatus made of polycarbonate resin was developed to estimate the effective diffusion (De) and sorption coefficients (Kd) that allowed large withdrawals from the source and collector cells and has enabled tests with low concentrations of radioactivity. An alternative to porous stainless steel filter plates has also been used to reduce uncertainty in test interpretation. Analysis of the transient data used a staged method of the Laplace transform to take into consideration the volume of the samples withdrawn from the apparatus during testing....
The potential association between xenotropic murine leukaemia virus-related gammaretrovirus (XMRV) and prostate cancer (PCa) has been documented since 2006. It is important for furthering our understanding of the biological mechanisms of PCa to ascertain whether this association is causal. To summarize the available information on the epidemiological and laboratory findings of the association, we conducted a literature search of the PubMed electronic database (from March 2006 to February 2011) to identify relevant published studies that examined the association between XMRV and PCa. Although several studies showed the positive association between XMRV and PCa, more recent studies did not support this conclusion. The positive findings might be due to contamination of human samples. Further ...
Clayey soils containing smectites are widely used for construction of liner and cover systems to reduce the hydraulic conductivity in geotechnical applications because of their low permeability and high cation exchange capacity. However, the compacted clayey soils crack on drying because of their high swelling potential, and their hydraulic conductivities increase. To solve this problem, it is essential to stabilize the clayey soils using additive materials. The aim of this study is to examine the suitability of silica fume as a stabilization material to reduce the development of desiccation cracks in compacted clayey liner and cover systems. Natural clayey soil and clayey soil?silica fume mixtures were compacted at the optimum moisture content and subjected to laboratory tests. The result...
The Idaho Explosives Detection System was developed at the Idaho National Laboratory (INL) to respond to threats imposed by delivery trucks potentially carrying explosives into military bases. A full-scale prototype system has been built and is currently undergoing testing. The system consists of two racks, one on each side of a subject vehicle. Each rack includes a neutron generator and an array of NaI detectors. The two neutron generators are pulsed and synchronized. A laptop computer controls the entire system. The control software is easily operable by minimally trained staff. The system was developed to detect explosives in a medium size truck within a 5-min measurement time. System performance was successfully demonstrated with explosives at the INL in June 2004 and at Andrews Air Force Base in July 2004.
Brookhaven National Laboratory is involved in a conceptual design study of a commercial nuclear power system which utilizes high-temperature electrolysis to produce synthetic fuels. The system is called HYFIRE. It includes a tokamak fusion power reactor supplying electrical and thermal energy to an array of electrolytes. The electrolytes produce hydrogen which can be used either directly as a fuel or in the production of hydrocarbons. The purpose of the study is to provide a mechanism for DOE to further assess the commercial potential of fusion using a tokamak reactor to produce synthetic fuel. The HYFIRE design is based on the tokamak commercial power reactor, STARFIRE. STARFIRE uses the deuterium/tritium/lithium fuel cycle. The HYFIRE study assumes the plasma shape and characteristics of STARFIRE study but uses a different blanket design. This study is particularly interested in the possibility of using the STARFIRE tokamak in the production ...
Summary 1. Plants express multiple defensive traits, but little is known about the genetic stability and phenotypic plasticity of these traits in nature. To investigate sources of variation and their potential ecological consequences for herbivores, we combined field observations of cyanogenic lima bean with laboratory experiments. 2. Field studies in South Mexico revealed a distinct variability of cyanogenic traits within and among wild lima bean populations. To differentiate among genetic variation and the impact of ambient conditions on plant phenotypes, we used seed grown plants as well as clones propagated from high (HC) and low cyanogenic (LC) wild type plants. 3. In growth chamber experiments, we cultivated plants under three intensities each of drought and salt stress, nutrient sup...
Four interrelated projects are underway whose purpose is to migrate the LAMPF-PSR Accelerator Complex control systems to a system with a common set of hardware and software components. Project goals address problems in performance, maintenance and growth potential. Front-end hardware, operator interface hardware and software, computer systems, network systems and data system software are being simultaneously upgraded as part of these efforts. The efforts are being coordinated to provide for a smooth and timely migration to a client-sever model-based data acquisition and control system. An increased use of the distributed intelligence at both the front-end and operator interface is a key element of the projects. 2 refs., 2 figs.
A design of a compact free-electron laser (FEL), generating ultra-fast, high-peak flux, XUV pulses is presented. The FEL is driven by ahigh-current, 0.5 GeV electron beam from the Lawrence Berkeley National Laboratory (LBNL) laser-plasma accelerator, whose active acceleration length is only a few centimeters. The proposed ultra-fast source (~;;10 fs) would be intrinsically temporally synchronized to the drive laser pulse, enabling pump-probe studies in ultra-fast science. Owing to the high current (>10 kA) of the laser-plasma-accelerated electron beams, saturated output fluxes are potentially greater than 10^13 photons/pulse. Devices based both on self-amplified spontaneous emission and high-harmonic generated input seeds, to reduce undulator length and fluctuations, are considered.
This Field Sampling Plan outlines the collection and analysis of samples in support of Phase IV of the Waste Area Group 10, Operable Units 6-05 and 10-04 remedial action. Phase IV addresses the remedial actions to areas with the potential for unexploded ordnance at the Idaho National Laboratory Site. These areas include portions of the Naval Proving Ground, the Arco High-Altitude Bombing Range, and the Twin Buttes Bombing Range. The remedial action consists of removal and disposal of ordnance by high-order detonation, followed by sampling to determine the extent, if any, of soil that might have been contaminated by the detonation activities associated with the disposal of ordnance during the Phase IV activities and explosives during the Phase II activities.
A compact and supersensitive device that can rapidly detect minute trace vapors from concealed explosives has been developed by scientists at Oak Ridge National Laboratory (ORNL). The new explosives sensor can detect and chemically identify organic nitrogen-oxygen compounds which are the building blocks of explosives such as TNT, plastiques, and nitroglycerine. The device could be used to scan persons entering airport terminals, nuclear power plants, defense installations, or other sensitive locations, providing greater security against potential terrorism. This device works on a glow discharge principle, and is more specifically called an ''Atmospheric Sampling Glow Discharge Ionization'' (ASGDI) source. The new detector is a highly automated, miniaturized version of research mass spectrometers widely used to trace constituents of chemical mixtures. Detail of this device's construction and ...
This report presents the results of an investigation into currently used methods for installation of underground high voltage power transmission cable, and offers recommendations for potentially improving these methods. Suggested enhancements cover the emplacement of both high pressure oil filled (HPOPT) pipe type and self contained oil filled (SCOF) cable systems. Cost comparisons of conventionally installed cable systems versus systems using proposed techniques and equipment are developed for a specific site selected for study. The report also documents the test results of laboratory experiments conducted to demonstrate the feasibility of using interference fit pipe couplings in place of welded pipe joints. 10 refs., 31 figs., 15 tabs.
Laboratory tests have been done to assess the feasibility of using microwaves to manufacture refractory liner boards as used in the steel industry. Results show that microwaves cured and dried the product about ten times faster than the conventional gas-oven process. The quality of boards dried with microwaves appears to be as good or better than of those dried with gas. The potential for fast, energy-optimized drying in a small space has been demonstrated. Economically, the energy-cost of using microwaves is comparable to using gas when drying the last 30% moisture content, that is, for about the last 50% of the present gas-drying time. For higher moisture contents, such as encountered in the early stages of drying, the energy can be supplied at a lower cost by gas. 8 figs.
In order to replace copper fungicides in organic potato production, 53 copper-free preparations (CFPs) based on natural compounds, including plant extracts and microorganisms, and five copper preparations were evaluated for their potential to control Phytophthora infestans, the pathogen that causes late blight of potatoes. In in vitro assays, 30% of the CFPs inhibited indirect germination of sporangia, 26% mycelial growth and in growth chamber experiments, 21% efficiently reduced foliar blight of tomato plants. In micro-plot field trials with applications twice a week, the copper preparations were the most effective and reduced foliar blight by 99%. Of the CFPs tested, Oekofluid P, Mycosin and other sulphuric clays, and C-2000 reduced late blight the most, from 63% to 37%. In small-plot tr...
Studies of asphalt emulsion sealants have demonstrated that the sealants are effective in containing radon and other potentially hazardous material within uranium tailings. The laboratory and field studies have further demonstrated that radon exhalation from uranium tailings piles can be reduced by greater than 99% to less than background levels. Field tests at the tailings pile in Grand Junction, Colorado confirmed that an 8-cm admix seal containing 22 wt % asphalt could be effectively applied with a cold-mix paver. Other techniques were successfully tested, including a soil stabilizer and a hot, rubberized asphalt seal that was applied with a distributor truck. After the seals were applied and conpacted, overburden was applied over the seal to protect the seal from ultraviolet degradation. 14 figures.
Anaphylaxis is a serious allergic reaction that is rapid in onset and sometimes leads to death. Understanding mechanisms, triggers, and patient-specific risk factors for severe or fatal anaphylaxis is critically important. Diagnosis of anaphylaxis is currently based on established clinical criteria. Epinephrine (adrenaline) is the first-line medication for anaphylaxis treatment and delay in injecting it contributes to biphasic reactions, hypoxic-ischemic encephalopathy, and fatality. Here, we focus on four important areas of translational research in anaphylaxis: studies of potential new biomarkers to support the clinical diagnosis of anaphylaxis, laboratory tests to distinguish allergen sensitization from clinical risk of anaphylaxis, the primary role of epinephrine (adrenaline) in anaphylaxis treatment, and strengthening the overall evidence base for anaphylaxis treatment. PMID:21668849
Investigatins into the welding of alloy 800 at the Reactor Fuel Element Laboratories, Springfields, commenced about three years ago following an extended development programme on tube to tube plate welding of low alloy and stainless steels for the Prototype Fast Reactor. The techniques and approach developed for critical fuel element welding applications had proved equally suitable for the precision welding requirements on the much heavier sections of heat exchangers. It had been demonstrated that the same control of weld quality and profile could be achieved with consistency and the permissible range of critical parameters could be readily defined. Because of this, development work was continued to include other materials, such as alloy 800, which might be of potential use. The tungsten inert gas (T.I.G.) arc welding process is used, and the equipment, including the control system, is described. Tube to tube-plate welding, and tube to tube ...
Alloy 800 has been used for steam generator (SG) tubing for more than 30 years, primarily in CANDU reactors and in reactors in Germany. Extensive laboratory testing and in-service experience suggest that the Alloy 800 tubing has excellent resistance to corrosion-related degradation under specified and appropriate operating conditions. In planning refurbishment of CANDU stations, a key concern is the longevity of existing SGs up to the 60 year lifetime of the refurbished plant. The paper reviews an existing methodology based on the concept of the improvement factor, and estimates it based on experimental data specific to CANDU operating conditions. The paper presents a more advanced probabilistic approach to estimate the degradation free lifetime distribution of Alloy 800 tubing, which is used to quantify the probability of degradation during the service life and to evaluate the impact of potential occurrences of degradation on reliability of SG ...
Alloy 800 has been used for steam generator (SG) tubing for more than 30 years, primarily in CANDU reactors and in reactors in Germany. Extensive laboratory testing and in-service experience suggest that the Alloy 800 tubing has excellent resistance to corrosion-related degradation under specified and appropriate operating conditions. In planning refurbishment of CANDU stations, a key concern is the longevity of existing SGs up to the 60 year lifetime of the refurbished plant. The paper reviews an existing methodology based on the concept of the improvement factor, and estimates it based on experimental data specific to CANDU operating conditions. The paper presents a more advanced probabilistic approach to estimate the degradation free lifetime distribution of Alloy 800 tubing, which is used to quantify the probability of degradation during the service life and to evaluate the impact of potential occurrences of degradation on reliability of SG ...
A microcosm laboratory experiment was conducted to determine the impact of biological reworking by the ragworm Nereis diversicolor on the redistribution of particle-bound radionuclides deposited at the sediment-water interface. Over the course of the 40-day experiment, as much as 35% of a {sup 137}Cs-labelled particulate tracer deposited on the sediment surface was redistributed to depths of up to 11 cm by the polychaete. Three different reworking models were employed to model the profiles and quantify the biodiffusion and biotransport coefficients: a gallery-diffuser model, a continuous sub-surface egestion model and a biodiffusion model. Although the biodiffusion coefficients obtained for each model were quite similar, the continuous sub-surface egestion model provided the best fit to the data. The average biodiffusion coefficient, at 1.8 {+-} 0.9 cm{sup 2} y{sup -1}, is in good agreement with the values quoted by other workers on the bioturbation effects of this ...
A microcosm laboratory experiment was conducted to determine the impact of biological reworking by the ragworm Nereis diversicolor on the redistribution of particle-bound radionuclides deposited at the sediment-water interface. Over the course of the 40-day experiment, as much as 35% of a "1"3"7Cs-labelled particulate tracer deposited on the sediment surface was redistributed to depths of up to 11 cm by the polychaete. Three different reworking models were employed to model the profiles and quantify the biodiffusion and biotransport coefficients: a gallery-diffuser model, a continuous sub-surface egestion model and a biodiffusion model. Although the biodiffusion coefficients obtained for each model were quite similar, the continuous sub-surface egestion model provided the best fit to the data. The average biodiffusion coefficient, at 1.8 #+-# 0.9 cm"2 y"-"1, is in good agreement with the values quoted by other workers on the bioturbation effects of this polychaete ...
Seismic stratigraphy based chronostratigraphic (SSBC) analysis of the Serbian Banat region allows the delineation of the spatial and stratigraphic relationships of the generally regressive and shallowing upward Neogene depositional fill of a tectonically unstable central portion of the Pannonian Basin. When geometrically restored in time and space, the sediment dispersal directions, sediment source directions, types of sedimentation breaks and the tectonic events influencing basin evolution can be delineated. For such an analysis the time-transgressive lithostratigraphic units used in the neighbouring Hungarian part of the Pannonian Basin are conveniently introduced based upon their characteristic seismic facies and constrained borehole log records as mappable seismic stratigraphic sequence units, termed "seismic operational sequences". The respective Neogene stage and operational sequence equivalents (Hungarian lithostratigraphic units or formations) are the Middle Miocene (Badenian, ...
The overall purpose of this project is to evaluate the biological and economic feasibility of restoring high-quality forests on mined land, and to measure carbon sequestration and wood production benefits that would be achieved from forest restoration procedures. In this quarterly report, we present a preliminary comparison of the carbon sequestration potential of forests growing on 14 mined sites in a seven-state region in the Midwestern and Eastern Coalfields. Carbon contents of these forests were compared to adjacent forests on non-mined land. The study was installed as a 3 x 3 factorial in a random complete block design with three replications at each location. The treatments include three forest types (white pine, hybrid poplar, mixed hardwood) and three silvicultural regimes (competition control, competition control plus tillage, competition control plus tillage plus fertilization). Each individual treatment plot is 0.5 acres. Each block of nine plots ...
Pollutants resulting from the management of solid waste have been shown to affect the air, land, oceans, and waterways. In addition, solid wastes have other, more indirect impacts such as reduction in feedstocks of natural resources, because useful materials are disposed of rather than recycled. The objective of this study is to evaluate solid waste management practices that have negative implications on the global environment and develop recommendations for reducing such impacts. Recommendations identifying needed changes are identified that will reduce global impacts of solid waste practices in the future. The scope of this study includes the range of non-hazardous solid wastes produced within our society, including municipal solid waste (MSW) and industrial solid waste (ISW), as well as industry-specific wastes from activities such as construction, demolition, and landclearing. Most solid waste management decisions continue to be made and implemented at very ...
Present and potential future changes to the global environment have important implications for marine pollution and for the air-sea exchange of both anthropogenic and natural substances. This report addresses three issues related to the potential impact of global change on the air-sea exchange of chemicals: Global change and the air-sea transfer of the nutrients nitrogen and iron. Global change and the air-sea exchange of gases. Oceanic responses to radiative and oxidative changes in the atmosphere. The deposition of atmospheric anthropogenic nitrogen has probably increased biological productivity in coastal regions along many continental margins. Atmospheric deposition of new nitrogen may also have increased productivity somewhat in mid-ocean regions. The projected future increases of nitrogen oxide emissions from Asia, Africa and South America will provide significant increases in the rate of deposition of oxidized ...
Due to current social and economical framework, in last years many nuclear power plant owners started a program for the Long Term Operation (LTO)/PLIM (Plant Life Management) of their older nuclear facilities. PLIM/PLEX has already been implemented in many countries (USA, Russia, etc.). This process has many nuclear safety implications, other than strategic and political ones. The need for tailoring the available safety assessment tools to such applications has become urgent in recent years and triggered many research actions. In particular, a PLIM framework requires both a detailed review of the features of the main safety programs (Maintenance, ISI, Surveillance) and a complete integration of these programs into the general management system of the plant. New external factors, such as: large use of subcontractors, need for efficient management of spare parts, request for heavy plant refurbishment programs demand for updated techniques in the overall management of ...
Heating during frictional sliding is a major component of the energy budget of earthquakes and represents a potential weakening mechanism. It is therefore important to investigate how heat dissipates during sliding on simulated faults. We present results from laboratory friction experiments where a halite (NaCl) slider held under constant load is dragged across a coarse substrate. Surface evolution and frictional resistance are recorded. Heat emission at the sliding surface is monitored using an infra-red camera. We demonstrate a link between plastic deformations of halite and enhanced heating characterized by transient localized heat spots. When sand 'gouge' is added to the interface, heating is more diffuse. Importantly, when strong asperities concentrate deformation, significantly more heat is produced locally. In natural faults such regions could be nucleation patches for melt production and hence potentially initiate ...
The Simplified Boiling Water Reactor (SBWR) designed by General Electric is a natural circulation reactor with enhanced safety features for potential accidents. It has a strong coupling between power and flow in the reactor core, hence the neutronic coupling with thermal-hydraulics is specially important. The potential geysering instability during the early part of a SBWR startup at low flow, low power and low pressure is of particular concern. The RAMONA-4B computer code developed at Brookhaven National Laboratory (BNL) for the SBWR has been used to simulate a SBWR startup transient and evaluate its stability, using a simplified four-channel representation of the reactor core for the thermal-hydraulics. This transient was run for 20,000 sec (5.56 hrs) in order to cover the essential aspect of the SBWR startup. The simulation showed that the SBWR startup was a very challenging event to analyze as it required accurate ...
The objective of this study was to determine if any fluids or materials used in the Exploratory Shaft Facility (ESF) of Yucca Mountain will make the mountain unsuitable for future construction of a nuclear waste repository. Yucca Mountain, an area on and adjacent to the Nevada Test Site in southern Nevada, USA, is a candidate site for permanent disposal of high-level radioactive waste from commercial nuclear power and defense nuclear activities. To properly characterize Yucca Mountain, it will be necessary to construct an underground test facility, in which in situ site characterization tests can be conducted. The candidate repository horizon at Yucca Mountain, however, could potentially be compromised by fluids and materials used in the site characterization tests. To minimize this possibility, Los Alamos National Laboratory was directed to evaluate the kinds of fluids and materials that will be used and their potential ...
In June 2009, the State of Hawaii enacted an Energy Efficiency Portfolio Standard (EEPS) with a target of 4,300 gigawatt hours (GWh) by 2030 (Hawaii 2009). Upon setting this goal, the Hawaii Clean Energy Initiative, Booz Allen Hamilton (BAH), and the National Renewable Energy Laboratory (NREL), working with select local stakeholders, partnered to execute the first key step toward attaining the EEPS goal: the creation of a high-resolution roadmap outlining key areas of potential electricity savings. This roadmap was divided into two core elements: savings from new construction and savings from existing buildings. BAH focused primarily on the existing building analysis, while NREL focused on new construction forecasting. This report presents the results of the Booz Allen Hamilton study on the existing building stock of Hawaii, along with conclusions on the key drivers of potential energy efficiency savings and on the steps ...
This official IEA report is a deliverable of IEA SHC Task 21/IEA BCS Annex 29: Daylight in Buildings. The Task focuses on daylighting systems and strategies which can be applied in new and existing buildings with a high potential electricity saving potential such as offices, schools, commercial, and institutional buildings. The daylighting performance of these strategies and systems is tested in laboratory facilities, through modeling, and in real case study buildings. This paper provides methods and procedures to evaluate the daylighting performance of real buildings. Annex 29 case studies located in Europe, North America, and Australia. It is a deliverable of Subtask D research projects. The main objective of Subtask D, as stated in the Implementing Agreement of Task 21/Annex 29, is `to demonstrate the viability of daylighting buildings in various world climatic zones as a means of achieving significant improvements in ...
Expedited site characterization (ESC), developed by Argonne National Laboratory, is an interactive, integrated process emphasizing the use of existing data of sufficient quality, multiple complementary characterization methods, and on-site decision making to optimize environmental site investigations. The Argonne ESC is the basis for the provisional ESC standard guide of the ASTM (American Society for Testing and Materials). QuickSite{sup SM} is the implementation package developed by Argonne to facilitate ESC of sites contaminated with hazardous wastes. At various sites, Argonne has successfully implemented QuickSite{sup SM} and demonstrated the technical superiority of the ESC process over traditional methodologies guided by statistics and random-sampling approaches. A key feature in the success of QuickSite{sup SM} investigations is achieving an understanding of the subsurface geologic and hydrogeologic controls and processes at a site before extensive sampling ...
Hematopoietic stem cells (HSCs) have remained at the forefront of stem cell research for the past 50 years, since the therapeutic potential of bone marrow transplantation was realized. Uniquely, among stem and progenitor cells, research progress has been made in parallel between the laboratory benchtop and hospital bedside during this period. Integral to this work has been the role of the transfusion medicine services in the collection, storage, and processing of HSCs. The next decade promises to bring further developments: with new fields of cellular therapies, stem cell vaccination, and stem cell drug testing opening up. This article summarizes exciting areas of research concerning the behavior and potential clinical applications of HSCs. For the purposes of clarity, we describe in turn the trafficking and transfer of HSCs; ex vivo expansion of HSC units from different sources; and finally, applications of specifically ...
This paper reports measurements of absolute differential cross sections for the direct scattering of oxygen atoms by He, Ne, Ar, Kr, Xe, H_2, N_2, O_2, CO, CO_2, H_2O, SO_2, NH_3, CH_4, CF_4, and SF_6 targets. The measured cross sections include contributions from all elastic and inelastic processes that result in a fast neutral oxygen atom product. Cross sections are presented for 0.5- and 1.5-keV projectile energies over the laboratory angular range 0.2 degree endash 5 degree. When compared in the center-of-mass reference frame, these cross sections exhibit a high degree of similarity in both amplitude and angular dependence. The cross sections for N_2, CO, CO_2, and H_2O are inverted using a partial-wave analysis to yield empirical interaction potentials, which can then be used to extrapolate the measurements down to lower energies. Using these potentials, cross sections are evaluated at 0.1 keV. copyright 1996 The ...
On July 18, 2001, a freight train carrying hazardous (non-nuclear) materials derailed and caught fire while passing through the Howard Street railroad tunnel in downtown Baltimore, Maryland. The United States Nuclear Regulatory Commission (USNRC), one of the agencies responsible for ensuring the safe transportation of radioactive materials in the United States, undertook an investigation of the train derailment and fire to determine the possible regulatory implications of this particular event for the transportation of spent nuclear fuel by railroad. Shortly after the accident occurred, the USNRC met with the National Transportation Safety Board (NTSB), the U.S. agency responsible for determining the cause of transportation accidents, to discuss the details of the accident and the ensuing fire. Following these discussions, the USNRC assembled a team of experts from the National Institute of Standards and Technology (NIST), the Center for Nuclear Waste Regulatory ...
The term Smith-Purcell free electron laser can be employed generally to describe any coherent radiation source in which a diffraction grating is used to couple an electron beam with the electromagnetic field. To date, most practical developments of this concept have focused on devices which operate in the millimeter spectral regime. In this paper construction of a Smith-Purcell free-electron laser operating in the far-infrared (FIR) region using a novel resonator cavity design and the electron beam from a low energy (0.5-5 MeV) radio-frequency accelerator will be discussed. A tunable source in this region would have many applications and since the beam energy is low, the small size and low overall cost of such a device would make it a laboratory instrument. Current projects which are progressing towards developing a FIR source are the programs at Stanford and CREOL. Both of these projects are using permanent magnet undulators to couple the electron beam with the ...
This paper describes research and development activities at the University of Regina, Saskatchewan, Canada on Optimization of CO{sub 2} Extraction Process Technologies. The ultimate goal of this research is to develop better and more effective CO{sub 2} separation processes which can be used to recover CO{sub 2} from industrial sources such as coal-fired power plants and coal gasification complexes at the lowest possible capital and operating costs. The research program has been supported by Saskatchewan Power Corporation, Saskatchewan Energy and Mines, Prairie Coal Ltd., the Canada Centre for Mineral and Energy Technology (CANMET), Fluor Daniel Inc. (USA), Sulzer Chemtech (Switzerland), Wascana Energy Inc., and Natural Sciences and Engineering Research Council of Canada (NSERC). Currently, six parallel and complementary projects have been carried out at the Process Systems Laboratory. These projects are: (1) Searching for new sterically hindered amines for high ...
The Department of Toxic Substance Control (DTSC) requested that Lawrence Livermore National Laboratory (LLNL) evaluate the treatment process currently employed at the Department's Stringfellow Superfund Site Pretreatment Plant (PTP) site to determine if wastes originating from the site were properly managed with regards to their radioactivity. In order to evaluate the current management strategy, LLNL suggested that DTSC characterize the effluents from the waste treatment system for radionuclide content. A sampling plan was developed; samples were collected and analyzed for radioactive constituents. Following is brief summary of those results and what implications for waste characterization may be made. (1) The sampling and analysis provides strong evidence that the radionuclides present are Naturally Occurring Radioactive Material (NORM). (2) The greatest source of radioactivity in the samples was naturally occurring uranium. The ...
The Department of Toxic Substance Control (DTSC) requested that Lawrence Livermore National Laboratory (LLNL) evaluate the treatment process currently employed at the Department's Stringfellow Superfund Site Pretreatment Plant (PTP) site to determine if wastes originating from the site were properly managed with regards to their radioactivity. In order to evaluate the current management strategy, LLNL suggested that DTSC characterize the effluents from the waste treatment system for radionuclide content. A sampling plan was developed; samples were collected and analyzed for radioactive constituents. Following is brief summary of those results and what implications for waste characterization may be made. (1) The sampling and analysis provides strong evidence that the radionuclides present are Naturally Occurring Radioactive Material (NORM). (2) The greatest source of radioactivity in the samples was naturally occurring uranium. The sample ...
Numerous laboratory investigations have shown that sulfur dioxide (SO/sub 2/) induces bronchoconstriction and respiratory symptoms in exercising asthmatics. These effects appear to depend on dose rate (the product of exposure concentration and ventilation rate), and may occur at dose rates attainable during outdoor exercise in SO/sub 2/-polluted communities. Effects are rapid in onset, requiring no more than 5 min of exercise during exposure. Thus they may be induced by transient elevations of SO/sub 2/ levels, which may occur near large pollution sources even when longer-term average concentrations meet existing air quality standards. Even very mild asthmatics typically are far more sensitive to SO/sub 2/ than healthy volunteers. The authors discuss an investigation designed to expand and improve the dose-response information on SO/sub 2/. In comparison to earlier work it employed a larger, clinically more diverse population of volunteer subjects. Comparatively ...
A geological study was conducted to better understand the nature of cleat development and degree of mineralization in coal seams of the Scollard and Coalspur Formations in western Alberta. The results can be applied to equivalent formations. The source and reservoir rocks of a coalbed methane (CBM) system were described. Coal seams are basically fractured reservoirs with 7 types of cleats. The field work involved cleat minerals sampling and determining cleat attributes such as type, strike and spacing from open-cut mines and outcrops. The laboratory work involved X-Ray diffraction, scanning electron microscopy, energy dispersive microscopy, stable isotope analysis, and fluid inclusions analysis. The study showed that coal seams of the Scollard and Coalspur Formations are widespread and cleated to various degrees. The face and butt cleats strike northeast-southwest and northwest southeast respectively along the structural grain of the Laramide Orogeny. The major ...
The Lake Superior region (Wisconsin, the Upper Peninsula of Michigan, and Minnesota) contains 41 Precambrian crystalline rock complexes comprising 64 individual but related rock bodies with known surface exposures. Each complex has a map area greater than 78 km/sup 2/. About 54% of the rock complexes have areas of up to 500 km/sup 2/, 15% fall between 500 km/sup 2/ and 1000 km/sup 2/, 19% lie between 1000 km/sup 2/ and 2500 km/sup 2/, and 12% are over 2500 km/sup 2/. Crystalline rocks of the region vary widely in composition, but they are predominantly granitic. Repeated thermo-tectonic events have produced early Archean gneisses, migmatites, and amphibolites with highly tectonized fabrics that impart a heterogeneous and anisotropic character to the rocks. Late Archean rocks are usually but not invariably gneissose and migmatitic. Proterozoic rocks of the region include synorogenic (foliated) granitic rocks, anorogenic (non-foliated) granites, and the layered ...
Arsenic was predominantly present as inorganic arsenite in the fronds of the hyperaccumulator Chinese brake. - Arsenic speciation is important not only for understanding the mechanisms of arsenic accumulation and detoxification by hyperaccumulators, but also for designing disposal options of arsenic-rich biomass. The primary objective of this research was to understand the speciation and leachability of arsenic in the fronds of Chinese brake (Pteris vittata L.), an arsenic hyperaccumulator, with an emphasis on the implications for arsenic-rich biomass disposal. Chinese brake was grown for 18 weeks in a soil spiked with 50 mg As kg"-"1 as arsenate (AsO_4"3"-), arsenite (AsO_3"3"-), dimethylarsinic acid (DMA), or methylarsonic acid (MMA). Plant samples were extracted with methanol/water (1:1) and arsenic speciation was performed using high performance liquid chromatography coupled with atomic fluorescence spectrometry. The impacts of air-drying on arsenic species and ...
This is the Fiscal Year 1995 Annual Report for the Advanced Manufacturing Science and Technology (AMST) sector of Los Alamos Tactical Goal 6, Industrial Partnering. During this past fiscal year, the AMST project leader formed a committee whose members represented the divisions and program offices with a manufacturing interest to examine the Laboratory`s expertise and needs in manufacturing. From a list of about two hundred interest areas, the committee selected nineteen of the most pressing needs for weapon manufacturing. Based upon Los Alamos mission requirements and the needs of the weapon manufacturing (Advanced Design and Production Technologies (ADaPT)) program plan and the other tactical goals, the committee selected four of the nineteen areas for strategic planning and possible industrial partnering. The areas selected were Casting Technology, Constitutive Modeling, Non-Destructive Testing and Evaluation, and Polymer Aging and Lifetime Prediction. For each ...
There have been many questions about the costs of providing medical services. These questions have resulted in the development of Resource-Based Relative Values Scale (RBRVS) at the national level. Policymakers view RBRVS as a potential tool to pay physicians. The questions, about the cost of operations of HSE-2 at Los Alamos National Laboratory, revolve around doing routine occupation health physicals for the Laboratory. Generally, these questions are concerned about why the costs appear to be high relative to what private physician suggests the costs should be. There is also an interest in trying to find methods to reduce these costs if possible. Many of the tools developed to help in construction estimating can be applied to estimating medical costs. With the need to perform many thousands of physicals each year the saving of even a few dollars for each exam can quickly add up to a large saving. There are a number of ...
This paper presents results of a laboratory and field study of naphthenic acid corrosion and the development of an effective chemical inhibitor for this type of corrosive attack. In the laboratory corrosion test, which involved 20 hour weight loss measurements in high flash solvent with a total acid number (TAN) of 16 mg KOH/gm at a temperature of 600 F (316 C), blank corrosion rates averaged 140 to 150 mpy (3.56 to 3.81 mm/y). Inhibited rates averaged about 10 to 12 mpy (0.254 to 0.305 mm/y). The field test was carried out on a heavy vacuum gas oil (HVGO) stream at 550 F (288 C) . Blanks varied from a high of 425 mpy (10.79 mm/y) for a 24 hour test to a low of about 100 mpy (2.54 mm/y) for a 150 hour test. Both electrical resistance (ER) probes and weight loss coupons showed corrosion rates below 5 mpy (0.127 mm/y) as long as they were adequately passivated. Passivation consisted of exposing the coupons to a high inhibitor dosage for a ...
In order to understand not only the mechanisms of earthquakes, but also the origin of diverse behavior of faults and plate boundaries, one must integrate (1) field studies on faults to understand deep intrafault processes, (2) laboratory work to reproduce those processes and determine mechanical and transport properties of fault zones, (3) theoretical and numerical studies analyzing fault motion, including earthquake generation processes, based on the constitutive properties determined by laboratory studies, and (4) seismological and geodetic studies revealing dynamic fault motion during earthquakes and diverse aseismic fault behavior. Ideally, such integrated studies should be carried out for a selected fault that produced an earthquake with good seismic/geodetic records so the prediction from (1) to (3) can be fully tested with (4), rather than selecting favorite data in the literature. Present session is organized to promote such integrated ...
Thermoplastic encapsulation has been extensively studied at Brookhaven National Laboratory`s (BNL) Environmental and Waste Technology Center (EWTC) as a waste encapsulation technology applicable to a wide range of waste types including radioactive, hazardous and mixed wastes. Encapsulation involves processing thermoplastic and waste materials into a waste form product by heating and mixing both materials into a homogeneous molten mixture. Cooling of the melt results in a solid monolithic waste form in which contaminants have been completely surrounded by a polymer matrix. Heating and mixing requirements for successful waste encapsulation can be met using proven technologies available in various types of commercial equipment. Processing techniques for thermoplastic materials, such as low density polyethylene (LDPE), are well established within the plastics industry. The majority of commercial polymer processing is accomplished using extruders, mixers or a ...
Because of the chaotic nature of the corrosion process and the complexity of the electrochemical noise signals that are generated, there is no generally accepted method of measuring and interpreting these signals that allows the consistent detection and identification of sustained localized pitting (SLP) as compared to general corrosion. We have reexamined electrochemical noise analysis (ENA) of localized corrosion using different hardware, signal collection, and signal processing designs than those used in conventional ENA techniques. The new data acquisition system was designed to identify and monitor the progress of SLP by analyzing the power spectral density (PSD) of the trend of the corrosion current noise level (CNL) and potential noise level (PNL). Each CNL and PNL data point was calculated from the root-mean- square value of the ac components of current and potential fluctuation signals, which were measured simultaneously during a short ...
Electron beams as a source of directed energy are under study at the Lawrence Livermore National Laboratory (LLNL). An intense 10-kA, 50-MeV, 50-ns full-width half-maximum, pulsed electron beam is generated by the prototype Advanced Test Accelerator (ATA) at the Laboratory's Site 300. Whenever the electron beam is stopped in materials, intense radiation is generated. Estimates based on available data in the literature show that for materials such as lead, photon radiation (x ray, gamma, bremsstrahlung) levels can be as large as 10"4 roentgens per pulse at 1 m in the zero-degree direction (i.e., the electron-beam direction). Neutrons, which are emitted isotropically, are produced at a level of 10"1"3 n/m"2 per pulse. Depending upon the number of pulses and the shielding geometry, the accumulated dose is potentially lethal to personnel and potentially damaging to instrumentation that may be used for ...
implications for treatment. In M.A. Chesney 8,. R. H. Rosenman (Eds.) Anqer and hostility in cardiovascular and behavioral disorders (pp. 103-126). ...
Mitochondrial dysfunction has been implicated in premature aging, age-related diseases, and tumor initiation and progression. Alterations of the mitochondrial genome accumulate both in aging tissue...Full Text Available
... In a HEAO 1 study of active galaxies, principally Seyfert 1s, in the 2, 165 keV energy range, Rothschild et al. ... As discussed by Rothschild et al. ...
Described as the body's largest organ, the skin is strategically located at the interface with the external environment where it has evolved to detect, integrate and respond to a diverse range...Full Text Available
sive star evolution based on our new calculations of this pulsational instability, where the initial mass of SNe progenitors increases according to the ...
This dissertation is devoted to the study of the phenomenological consequences of the three-generation heterotic string models based on the Calabi-Yau compactifications and the N = 2 superconformal constructions.
Schizophrenia is a heterogeneous psychiatric disorder in which multiple neurotransmitter systems have been implicated. Increased and decreased dopamine transmission in the subcortical meso-limbic and...Full Text Available
BackgroundFloating knee injuries are usually associated with other significant injuries. Do these injuries have implications on the management of the floating knee and the final...Full Text Available
and the implications for massive star evolution. In recent years, the complex nature of the circumstellar regions of evolved massive stars has become apparent. ...
Periodontitis is an infectious process characterized by inflammation affecting the supporting structures of the teeth. Porphyromonas gingivalis is a major oral bacterial species implicated...Full Text Available
Jan 7, 2010 ... Deforestation. The environmental implications of the word are as numerous as the syllables. And scientists like Jim Collatz have the job of ...
Phosphorylation is one of the most frequent modifications in intracellular signaling and is implicated in many processes ranging from transcriptional control to signal transduction in innate immunity....Full Text Available
The importance of designating criteria for diagnosing dementia lies in its implications for clinical treatment, research, caregiving, and decision-making. Dementia diagnosis in Huntington's...Full Text Available
Although coagulase-negative staphylococci (C-NS) have been implicated in certain human infections, they are generally regarded as contaminants, and their clinical significance is questioned. To assess...Full Text Available
A brief review of standard big bang nucleosynthesis theory and the related observations of the light element isotopes is presented. Implications of BBN on chemical evolution and constraints on particle properties will also be discussed.
The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter...Full Text Available
DescriptionThis Studentship will focus on the implications of material nutrition and health for reproduction in green turtles, and specifically the role played by dietary carotenoids.
In January 2001, Husky Oil Operations Limited (Husky), in joint-venture with Petro-Canada, submitted a Benefits Plan for the White Rose Development to the Canada- Newfoundland and Labrador Offshore Petroleum Board (C-NLOPB). This revised document provided the case for requesting an increase in the facility maximum daily production rate and the average annual production rate for the White Rose field from 100,000 barrels per day (bpd) as stated in the approved White Rose Development Plan to 140,000 bpd. In order to determine the potential for increasing oil production through the Floating Production, Storage and Offloading (FPSO) vessel, two things were considered, namely the proper reservoir management of the White Rose field to ensure optimum resource recovery, and the capacity of the FPSO topsides processing system and supporting utilities to accommodate increased production. This document presented a detailed review of all the implications of ...
Vascular endothelial growth factor (VEGF) is a mitogen that is critically involved in vasculogenesis, angiogenesis, and hematopoiesis. However, what and how transcription factors participate in the regulation of vegf gene expression are not fully understood. Here we report the cloning and sequencing of the zebrafish vegf promoter which revealed that the promoter contains a number of bone morphogenetic protein (BMP)-activated Smad binding elements (SBE), implicating Smad1 and Smad5 in the regulation of BMP-induced expression of vegf. Electrophoretic mobility shift assays of adding recombinant Smad proteins to the SBE-containing DNA oligonucleotides that represent portions of zebrafish vegf promoter resulted in mobility shift of the oligonucleotides. These changes demonstrate potential interactions between Smad1/5 and the vegf promoter. Reporter activity assays using the wild-type or SBE-deleted vegf promoters to drive the luciferase reporter ...
This report describes the basis, results, and related risk implications of an analysis performed by an ad hoc working group of the U.S. Nuclear Regulatory Commission (NRC) to assess the containment bypass potential attributable to steam generator tube rupture (SGTR) induced by severe accident conditions. The SGTR Severe Accident Working Group, comprised of staff members from the NRC`s Offices of Nuclear Reactor Regulation (NRR) and Nuclear Regulatory Research (RES), undertook the analysis beginning in December 1995 to support a proposed steam generator integrity rule. The work drew upon previous risk and thermal-hydraulic analyses of core damage sequences, with a focus on the Surry plant as a representative example. This analysis yielded new results, however, derived by predicting thermal-hydraulic conditions of selected severe accident scenarios using the SCDAP/RELAP5 computer code, flawed tube failure modeling, and tube failure probability ...
Although the public generally hold positive attitudes towards wind energy, proposals for the construction of new wind farms are often met with strong resistance. In New Zealand, where the government has recently introduced ambitious policy targets for renewable energy generation, negative perceptions of wind farms are increasingly evident and have the potential to prevent the achievement of these targets. This research sets out to examine what influences social resistance to wind farms in New Zealand. Drawing from public submissions on three wind farm proposals, a framework developed by Devine-Wright [Devine-Wright, P., 2005a. Beyond NIMBYism: towards an integrated Framework for Understanding Public Perceptions of Wind Energy. Wind Energy 8, 125-139.] was used as the basis for identification of factors affecting public perceptions of wind farms. The research found firstly that there was no apparent relationship between the proximity of submitters to a proposed wind ...
Although the public generally hold positive attitudes towards wind energy, proposals for the construction of new wind farms are often met with strong resistance. In New Zealand, where the government has recently introduced ambitious policy targets for renewable energy generation, negative perceptions of wind farms are increasingly evident and have the potential to prevent the achievement of these targets. This research sets out to examine what influences social resistance to wind farms in New Zealand. Drawing from public submissions on three wind farm proposals, a framework developed by Devine-Wright [Devine-Wright, P., 2005a. Beyond NIMBYism: towards an integrated Framework for Understanding Public Perceptions of Wind Energy. Wind Energy 8, 125-139.] was used as the basis for identification of factors affecting public perceptions of wind farms. The research found firstly that there was no apparent relationship between the proximity of submitters to a proposed wind ...
Most prior climate change assessments for U.S. agriculture have focused on major world food crops such as wheat and maize. While useful from a national and global perspective, these results are not particularly relevant to the Northeastern U.S. agriculture economy, which is dominated by dairy milk production, and high-value horticultural crops such as apples (Malus domestica), grapes (vitis vinifera), sweet corn (Zea mays var. rugosa), cabbage (Brassica oleracea var. capitata), and maple syrup (sugar maple, Acer saccharum). We used statistically downscaled climate projections generated by the HadCM3 atmosphere-ocean general circulation model, run with Intergovernmental Panel on Climate Change future emissions scenarios Alfi (higher) and B1 (lower), to evaluate several climate thresholds of direct relevance to agriculture in the region. A longer (frostfree) growing season could create new opportunities for farmers with enough capital to take risks on new crops (assuming a market for new ...
Thermal (gas) nitridation of stainless steels can yield low interfacial contact resistance (ICR), electrically-conductive and corrosion-resistant nitride containing surfaces (Cr2N, CrN, TiN, V2N, VN, etc) of interest for fuel cells, batteries, and sensors. This paper presents the results of scale up studies to determine the feasibility of extending the nitridation approach to thin 0.1 mm stainless steel alloy foils for proton exchange membrane fuel cell (PEMFC) bipolar plates. A major emphasis was placed on selection of alloy foil composition and nitidation conditions potentially capable of meeting the stringent cost goals for automotive PEMFC applications. Developmental Fe-20Cr-4V alloy and type 2205 stainless steel foils were treated by pre-oxidation and nitridation to form low-ICR, corrosion-resistant surfaces. Promising behavior was observed under simulated aggressive anode- and cathode- side bipolar plate conditions for both materials. Variation in ICR values ...
(3H)Cyclofoxy (CF: 17-cyclopropylmethyl-3,14-dihydroxy-4,5-alpha-epoxy-6-beta-fluoromorp hinan) is an opioid antagonist with affinity to both mu and kappa subtypes that was synthesized for quantitative evaluation of opioid receptor binding in vivo. Two sets of experiments in rats were analyzed. The first involved determining the metabolite-corrected blood concentration and tissue distribution of CF in brain 1 to 60 min after i.v. bolus injection. The second involved measuring brain washout for 15 to 120 s following intracarotid artery injection of CF. A physiologically based model and a classical compartmental pharmacokinetic model were compared. The models included different assumptions for transport across the blood-brain barrier (BBB); estimates of nonspecific tissue binding and specific binding to a single opiate receptor site were found to be essentially the same with both models. The nonspecific binding equilibrium constant varied modestly in different brain structures (Keq = ...
Thermoluminescence (TL) and Electron Paramagnetic Resonance (EPR) dosimetry were used to measure dose effects in borosilicate glass with time, from 10 minutes to #approx#60 days following exposure to a dose of up to 10,000 Rad. TL and EPR results were consistent and performed similarly, with both techniques capable of achieving an estimated limit of detection of between 50-100 Rad. Three peaks were identified in the TL glow curve at roughly 110 C, 205 C, and 225 C. The intensity of the 205 C peak was the dominant peak over the time period of this study. The stability of all of the peaks with time since irradiation increased with their corresponding temperature and little or no variation was observed in the glow curve response to a specified total dose attained at different dose rates. The intensity of the 205 C peak decreased logarithmically with time regardless of total dose. Based upon a conservative limit of detection of 330 Rad, a 10,000 Rad dose would still be detected 2.7E3 years ...
Commercial focused ion beam (FIB) systems are commonly used to image integrated circuits (ICS) after device processing, especially in failure analysis applications. FIB systems are also often employed to repair faults in metal lines for otherwise functioning ICS, and are being evaluated for applications in film deposition and nanofabrication. A problem that is often seen in FIB imaging and repair is that ICS can be damaged during the exposure process. This can result in degraded response or out-right circuit failure. Because FIB processes typically require the surface of an IC to be exposed to an intense beam of 30--50 keV Ga{sup +} ions, both charging and secondary radiation damage are potential concerns. In previous studies, both types of effects have been suggested as possible causes of device degradation, depending on the type of device examined and/or the bias conditions. Understanding the causes of this damage is important for ICS that are imaged or repaired ...
These studies have addressed firstly the effect of single small doses of x-ray upon murine hematopoietic stem cells to obtain a better estimate of the D/sub q/. It is small, of the order of 20 rads. Secondly, a dose fractionation schedule tht does not kill or perturb the kinetics of hemopoietic cell proliferation was sought in order to investigate the leukemogenic potential of low level radiation upon an unperturbed hemopoietic system. The studies reported herein show tht 1.25 rads every other day decrease the CFU-S content of bone marrow by the time 40 rads are accumulated. Studies on the effect of 0.5, 1.0, 2.0, and 3.0 rads 3 times per week are under way. Two rads 3 times per week produced a modest decrease in CFU-S content of bone marrow after an accumulation of 68 rads. With 3.0 rads 3 times per week an accumulation of 102 rads produces a significant decrease in CFU-S content of bone marrow. Dose fractionation at 0.5 and 1.0 rad 3 times per week has not ...
By the use of thermoluminescence (TL) technique we have investigated the effects of gamma irradiation on the TL response of pulverised natural zircon (ZrSiO{sub 4}) crystals from the Jos Plateau area of Nigeria. Samples of the mineral that have been previously annealed were artificially irradiated to moderate gamma doses ranging from 0.7 to 4.9 Gy using {sup 60}Co gamma-source of the CERD. The natural TL glow curve of the sample showed a broad peak around 250 deg. C, the peak was however, found to be completely erased following heat treatment for 2 h at 400 deg. C. The TL glow curves of the artificially irradiated samples showed two overlapping glow peaks at about 112 deg. C (peak I) and at 156 deg. C (peak II) within the dose range utilised. We note that the natural TL peak appears to be different from the two observed in the artificially irradiated sample. The TL response with dose was investigated for the two glow peaks found in the artificially irradiated sample and in both cases, ...
By the use of thermoluminescence (TL) technique we have investigated the effects of gamma irradiation on the TL response of pulverised natural zircon (ZrSiO_4) crystals from the Jos Plateau area of Nigeria. Samples of the mineral that have been previously annealed were artificially irradiated to moderate gamma doses ranging from 0.7 to 4.9 Gy using "6"0Co gamma-source of the CERD. The natural TL glow curve of the sample showed a broad peak around 250 deg. C, the peak was however, found to be completely erased following heat treatment for 2 h at 400 deg. C. The TL glow curves of the artificially irradiated samples showed two overlapping glow peaks at about 112 deg. C (peak I) and at 156 deg. C (peak II) within the dose range utilised. We note that the natural TL peak appears to be different from the two observed in the artificially irradiated sample. The TL response with dose was investigated for the two glow peaks found in the artificially irradiated sample and in both cases, in the ...
The Canadian Soldier Information Requirements Technology Demonstration (SIREQ TD) soldier modernization research and development program has conducted experiments to help determine the types and amount of information needed to support wayfinding across a range of terrain environments, the most effective display modality for providing the information (visual, auditory or tactile) that will minimize conflict with other infantry tasks, and to optimize interface design. In this study, seven different visual helmet-mounted display (HMD) designs were developed based on soldier feedback from previous studies. The displays and an in-service compass condition were contrasted to investigate how the visual HMD interfaces influenced navigation performance. Displays varied with respect to their information content, frame of reference, point of view, and display features. Twelve male infantry soldiers used all eight experimental conditions to locate bearings to waypoints. From a constant location, ...
No research has compared expressions of weight bias across different subgroups of obese individuals. This study compared attitudes toward and beliefs about obesity in women with and without binge eating disorder (BED) and examined whether these attitudes are related to psychological factors. Fifty obese women with BED were compared with an age- and body mass index (BMI)-matched group of 50 obese women without BED on a battery of established measures of anti-fat attitudes and beliefs about weight controllability and psychological factors (self-esteem, depression, and eating disorder features). The ageand BMI-matched groups did not differ with respect to beliefs about obesity or attitudes toward obese persons, or in self-esteem or depression. Correlational analyses conducted separately within each group revealed that women with BED who reported more favorable attitudes towards obese persons had higher self-esteem and lower levels of depression, whereas there were no significant ...
Three independent studies have been conducted for assessing the impact of rocket launches on the earth`s environment. These studies have addressed issues of acid rain in the troposphere, ozone depletion in the stratosphere, toxicity of chemical rocket exhaust products, and the potential impact on global warming from carbon dioxide emissions from rocket launches. Local, regional, and global impact assessments were examined and compared with both natural sources and anthropogenic sources of known atmospheric pollutants with the following conclusions: (1) Neither solid nor liquid rocket launches have a significant impact on the earth`s global environment, and there is no real significant difference between the two. (2) Regional and local atmospheric impacts are more significant than global impacts, but quickly return to normal background conditions within a few hours after launch. And (3) vastly increased space launch activities equivalent to 50 U.S. Space Shuttles or ...
The Chinese government has enacted policies to promote alternative vehicle fuels (AVFs) and alternative fuel vehicles (AFVs), including city bus fleets. The life cycle (LC), energy savings (ES) and GHG reduction (GR) profiles of AVFs/AFVs are critical to those policy decisions. The well-to-wheels module of the Tsinghua-CA3EM model is employed to investigate actual performance data. Compared with conventional buses, AFVs offer differences in performance in terms of both ES and GR. Only half of the AFVs analyzed demonstrate dual benefits. However, all non-oil/gas pathways can substitute oil/gas with coal. Current policies seek to promote technology improvements and market creation initiatives within the guiding framework of national-level diversification and district-level uniformity. Combined with their actual LC behavior and in keeping with near- and long-term strategies, integrated policies should seek to (1) apply hybrid electric technology to diesel buses; (2) encourage NG/LPG buses ...
There are a multitude of cost centers in the typical coal mine, and almost as many ways to calculate their individual and collective effect on the bottom line. The costs of explosives is, in some ways, very difficult to determine without consideration of drilling, loading, hauling and breaking costs. Saving a nickel in explosive costs, for example, could end up costing a dollar more in crushing expenses. Typically, mines request quotations for explosives products on a weight basis. Were the market one of pure commodities, this would give a valid comparison. However, the energy being purchased often is not considered. The cost of any explosive should be considered in light of the work it can do, not the air it displaces or the price per pound. Consider in essence, the purchase of explosive energy as you would the sale of coal, in terms of dollars per Btu. Recent new developments in explosives technology make the economic implications of blast design and explosive ...
Ab initio total energy calculations within the framework of density functional theory have been performed for atomic hydrogen and oxygen chemisorption on the (0001) surface of double hexagonal packed (dhcp) americium using a full-potential all-electron linearized augmented plane wave plus local orbitals method. Chemisorption energies were optimized with respect to the distance of the adatom from the relaxed surface for three adsorption sites, namely top, bridge, and hollow hcp sites, the ad-layer structure corresponding to the coverage of a 0.25 monolayer in all cases. Chemisorption energies were computed at the scalar-relativistic level (no spin-orbit coupling NSOC) and at the fully relativistic level (with spin-orbit coupling SOC). The two-fold bridge adsorption site was found to be the most stable site for O at both the NSOC and SOC theoretical levels with chemisorption energies of 8.204 eV and 8.368 eV respectively, while the three-fold hollow hcp adsorption ...
The tendency of welded joints from 10Kh14AG15 and 10Kh14AG9 steels to pitting corrosion under the conditions of operating blast-furnace gas purification scrubbers has been investigated. Water in scrubbers contains various quantities of chlorides and sulfates, has pH from 6 to 9 and temperature 65-75 deg. The laboratory corrosion tests have been carried out also on samples turned from the heat-affected zone (h.a.z.) of welded plates at 20 and 65 deg. Anode polarization curves have been read from the Vk corrosion potential at potential shifting rate 0.01 V/min. It is established that in most rigid conditions of scrubbers operating pitting corrosion (PC) rate of chrome-manganese nitrogen-containing steel can reach 2.5 mm/year. At high content of chlorides in water the elevated temperature and external tensile stresses intensify PC. The resistance of welded joints to PC when using welding materials on chromonickel molybdenum ...
This report is the first of four volumes that identify and assess the environmental, health, and safety issues involved in using sodium-sulfur (Na/S) battery technology as the energy source in electric and hybrid vehicles that may affect the commercialization of Na/S batteries. This and the other reports on recycling, shipping, and vehicle safety are intended to help the Electric and Hybrid Propulsion Division of the Office of Transportation Technologies in the US Department of Energy (DOE/EHP) determine the direction of its research, development, and demonstration (RD&D) program for Na/S battery technology. The reports review the status of Na/S battery RD&D and identify potential hazards and risks that may require additional research or that may affect the design and use of Na/S batteries. This volume covers cell design and engineering as the basis of safety for Na/S batteries and describes and assesses the potential chemical, ...
This report is the first of four volumes that identify and assess the environmental, health, and safety issues involved in using sodium-sulfur (Na/S) battery technology as the energy source in electric and hybrid vehicles that may affect the commercialization of Na/S batteries. This and the other reports on recycling, shipping, and vehicle safety are intended to help the Electric and Hybrid Propulsion Division of the Office of Transportation Technologies in the US Department of Energy (DOE/EHP) determine the direction of its research, development, and demonstration (RD D) program for Na/S battery technology. The reports review the status of Na/S battery RD D and identify potential hazards and risks that may require additional research or that may affect the design and use of Na/S batteries. This volume covers cell design and engineering as the basis of safety for Na/S batteries and describes and assesses the potential chemical, electrical, and ...
The issue of projecting policies ensuring appropriate energy supply in the future has become more important in Germany after conclusion of the agreement on a long-term nuclear power phase-out. A recent comparative analysis of a selection of scientific studies forecasting the implications of a nuclear power phase-out has shown that there is demand for more studies examining the issue in greater detail, and on the basis of an enlarged scope of research topics. Hence the present study, intended as a preliminary analysis, will investigate the potential, conditions of successful application, conceivable support schemes, and effects of those policy options that in any case, apart from the nuclear power phase-out scenario, are of essential importance in the context of building the proper conditions for sustainable development of Germany's energy sector. The options and strategies examined are: stepping up energy efficiency programmes and ...
On July 18, 2001, a freight train carrying hazardous (non-nuclear) materials derailed and caught fire while passing through the Howard Street railroad tunnel in downtown Baltimore, Maryland. The United States Nuclear Regulatory Commission (USNRC), one of the agencies responsible for ensuring the safe transportation of radioactive materials in the United States, undertook an investigation of the train derailment and fire to determine the possible regulatory implications of this particular event for the transportation of spent nuclear fuel by railroad. Shortly after the accident occurred, the USNRC met with the National Transportation Safety Board (NTSB, the U.S. agency responsible for determining the cause of transportation accidents), to discuss the details of the accident and the ensuing fire. Following these discussions, the USNRC assembled a team of experts from the National Institute of Standards and Technology (NIST), the Center for Nuclear Waste Regulatory ...
This report documents a case history in which a cadaver and the associated burial objects were found well preserved after being buried for more than 2100 years in Southern China. The preservation is attributed to a layer of kaolin that surrounded the coffin and served as a barrier to water and air movement. The implications for the disposal of nuclear fuel waste are discussed.
DescriptionNanotechnology is rapidly expanding, and is forecast to become a trillion dollar industry in the near future. It is inevitable that as nanotechnology applications increase, increasing amounts of manufactured nanoparticles (mNPs) will be released into the environment. The environmental and human health implications of the release of most of the huge range of possible particle types are as yet largely unknown, but in the context of groundwaters, apart from implications for the drinking of contam [continued...
Full text: The ITWG was first formed in 1995 for the purpose of fostering international cooperation for combating illicit trafficking of nuclear materials. The initial focus for the ITWG was on the development of nuclear forensics to help answer attribution questions regarding nuclear materials of unknown origin. More recently, the ITWG has also expanded its focus to include detection of nuclear materials during transit. This paper presents some of the key developments by this group and their potential impact for combating nuclear smuggling. The initial focus of the ITWG was to write a status report on international cooperation on nuclear smuggling forensic analysis. This 26-page report summarized previous work on nuclear forensics and gave an initial analysis on prioritizing techniques and methods for forensic analysis regarding source and route attribution. This report was submitted to the G-8 countries, and shortly thereafter, nuclear forensics was endorsed at ...
Wireline well logs have three general uses in geothermal exploration and reservoir evaluation: reservoir parameter analysis, lithologic column determination, and reservoir size resolution. Reservoir flow testing data are acquired to understand the flow rate, life, and production potential of the geothermal reservoir. These data are a coarse subsurface measurement of the geothermal prospect. Wireline logs acquired from wells in a geothermal prospect are used to define in detail, or estimate the reservoir parameters of temperature, thickness, lateral size, amount of fracture and intergranular pore space, and the quantity and quality of fluid that might be produced. Laboratory measurements can be made on core samples and drill cuttings samples to define the intrinsic behavior of the materials and fluid that compose the geotheraml reservoir. Wireline log measurements are needed to correlate and link the reservoir testing and core analysis, reduce ...
Nuclear fuel cycle activities of the former Soviet Union (FSU) have resulted in massive contamination of the environment in western Siberia. We are developing three-dimensional numerical models of the hydrogeology and potential contaminant migration in the West Siberian Basin. Our long-term goal at Pacific Northwest Laboratory is to help determine future environmental and human impacts given the releases that have occurred to date and the current waste management practices. In FY 1993, our objectives were to (1) refine and implement the hydrogeologic conceptual models of the regional hydrogeology of western Siberia developed in FY 1992 and develop the detailed, spatially registered digital geologic and hydrologic databases to test them, (2) calibrate the computer implementation of the conceptual models developed in FY 1992, and (3) develop general geologic and hydrologic information and preliminary hydrogeologic conceptual models relevant to ...
One approach to validate nuclear power plant (NPP) signals makes use of pattern recognition techniques. This approach often assumes that there is a set of signal prototypes that are continuously compared with the actual sensor signals. These signal prototypes are often computed based on empirical models with little or no knowledge about physical processes. A common problem of all data-based models is their limited ability to make predictions on the basis of available training data. Another problem is related to suboptimal training algorithms. Both of these potential shortcomings with conventional approaches to signal validation and sensor operability validation are successfully resolved by adopting a recently proposed learning paradigm called the support vector machine (SVM). The work presented here is a novel application of SVM for data-based modeling of system state variables in an NPP, integrated with a nonlinear, nonparametric technique called the multivariate ...
The Integrated Solar Upper Stage (ISUS) Program at the USAF Phillips Laboratory is directed at demonstrating a solar bimodal power and propulsion system for military applications. Trades were performed to examine the potential performance of the ISUS stage combined with the proposed LLV-3 launch vehicle. Variation in ISUS thermal power directly affects the trip time from LEO to GEO. These variations can be altered by changing average propellant temperature raising or lowering the average specific impulse. If the ISUS system is sized for the spacecraft`s electrical power requirements, this can result in long trip times for high mass satellites with low electrical power requirements. The ISUS can be sized, however, for a suitable thermal power to allow more rapid trip times with minimum impact on delivered mass. Such a system can place significantly more payload in GEO than a solid chemical stage. The mass advantages of the ISUS increase as ...
This paper presents the conceptual framework that is being used to define quantification of margins and uncertainties (QMU) for application in the nuclear weapons (NW) work conducted at Sandia National Laboratories. The conceptual framework addresses the margins and uncertainties throughout the NW life cycle and includes the definition of terms related to QMU and to figures of merit. Potential applications of QMU consist of analyses based on physical data and on modeling and simulation. Appendix A provides general guidelines for addressing cases in which significant and relevant physical data are available for QMU analysis. Appendix B gives the specific guidance that was used to conduct QMU analyses in cycle 12 of the annual assessment process. Appendix C offers general guidelines for addressing cases in which appropriate models are available for use in QMU analysis. Appendix D contains an example that highlights the consequences of different ...
In this paper, we put forward a systematic method to analyze, control and evaluate the safety issues of medical robotics. We created a safety model that consists of three axes to analyze safety factors. Software and hardware are the two material axes. The third axis is the policy that controls all phases of design, production, testing and application of the robot system. The policy was defined as hazard identification and safety insurance control (HISIC) that includes seven principles: definitions and requirements, hazard identification, safety insurance control, safety critical limits, monitoring and control, verification and validation, system log and documentation. HISIC was implemented in the development of a robot for urological applications that was known as URObot. The URObot is a universal robot with different modules adaptable for 3D ultrasound image-guided interstitial laser coagulation, radiation seed implantation, laser resection, and electrical resection of the prostate. ...
The Mixed Waste Management Facility, or MWMF, has been proposed as a national testbed facility for the demonstration and evaluation of technologies that are alternatives to incineration for the treatment of mixed low-level waste. The facility design will enable evaluation of technologies at pilot scale, including all aspects of the processes, from receiving and feed preparation to the preparation of final forms for disposal. The MWMF will reduce the risk of deploying such technologies by addressing the following: (1) Engineering development and scale-up. (2) Process integration and activation of the treatment systems. (3) Permitting and stakeholder issues. In light of the severe financial constraints imposed on the DOE and federal programs, DOE/HQ requested a study to assess the cost benefit for the MWMF given other potential alternatives to meet waste treatment needs. The MVVMF Project was asked to consider alternatives specifically associated with ...
There is an urgent need to monitor the condition of fluid-filled taped (FFT) cables. The Dissolved-Gas Analysis (DGA) technique that has been successfully applied to power transformers holds great potential for the preventive maintenance of FFT cables. However, before this emerging technique can be properly applied to cables, a suitable fluid sampling and subsequent gas analysis method had to be developed, including the generation of both laboratory and field data to aid in data interpretation. Data on gas saturation levels in various cable fluids have been presented. This paper describes a novel method developed specifically for FFT cables and discusses field results so obtained. The type, distribution and concentration of gases from fluid alone and paper alone under electrical stress has been presented, including the differences between normal and not-so-normal cable systems as demonstrated by DGA. The concept of wet tensile strength has been ...
The Nuclear Regulatory Commission (NRC), working with the National Institute of Standards and Technology (NIST), Pacific Northwest National Laboratory (PNNL), and the National Transportation Safety Board (NTSB), performed analyses to predict the response of various spent fuel transportation cask designs when exposed to a fire similar to that which occurred in the Howard Street railroad tunnel in downtown Baltimore, Maryland on July 18, 2001. The thermal performance of three different spent fuel cask designs (HOLTEC HI-STAR 100, TransNuclear TN-68, and NAC-LWT) was evaluated with the ANSYSR and COBRA-SFS analysis codes, utilizing boundary conditions for the tunnel fire obtained using NIST's Fire Dynamics Simulator (FDS) code. NRC Staff evaluated the potential for a release of radioactive material from each of the three transportation casks analyzed for the Baltimore tunnel fire scenario. The results of these analyses are described in detail in ...
The ability to use an acoustic stethoscope to detect lung and/or heart sounds, and then to then communicate one's interpretation of those sounds is an essential skill for many medical professionals. Interpretation of lung and heart sounds, in the context of history and other examination findings, often aids the differential diagnosis. Bedside assessment of changing auscultation findings may also guide treatment. Learning lung and heart auscultation skills typically involves listening to pre-recorded normal and adventitious sounds, often followed by laboratory instruction to guide stethoscope placement, and finally correlating the sounds with the associated pathophysiology and pathology. Recently, medical simulation has become an important tool for teaching prior to clinical practice, and for evaluating bedside auscultation skills. When simulating cardiovascular or pulmonary problems, high-quality lung and heart sounds should be able to accurately corroborate other ...
Protecting sensitive items from undetected tampering in an unattended environment is crucial to the success of non-proliferation efforts relying on the verification of critical activities. Tamper Indicating Packaging (TIP) technologies are applied to containers, packages, and equipment that require an indication of a tamper attempt. Examples include: the transportation and storage of nuclear material, the operation and shipment of surveillance equipment and monitoring sensors, and the retail storage of medicine and food products. The spectrum of adversarial tampering ranges from attempted concealment of a pin-hole sized penetration to the complete container replacement, which would involve counterfeiting efforts of various degrees. Sandia National Laboratories (SNL) has developed a technology base for advanced TIP materials, sensors, designs, and processes which can be adapted to various future monitoring systems. The purpose of this technology base is to ...
A compact, quasi-4? position sensitive silicon array, TIARA, designed to study direct reactions induced by radioactive beams in inverse kinematics is described here. The Transfer and Inelastic All-angle Reaction Array (TIARA) consists of 8 resistive charge division detectors forming an octagonal barrel around the target and a set of double-sided silicon-strip annular detectors positioned at each end of the barrel. The detector was coupled to the ?-ray array EXOGAM and the spectrometer VAMOS at the GANIL Laboratory to demonstrate the potential of such an apparatus with radioactive beams. The 14N(d,p)15N reaction, well known in direct kinematics, has been carried out in inverse kinematics for that purpose. The observation of the 15N ground state and excited states at 7.16 and 7.86 MeV is presented here as well as the comparison of the measured proton angular distributions with DWBA calculations. Transferred l-values are in very good agreement ...
Irradiation of live bivalve molluscs is a promising new technique to reduce the public health threats of viral and bacterial pathogens in the consumption of raw shellfish. In studies conducted within the past year, live hardshelled clams and oysters were innoculated with Simian Rotavirus SA-11, Poliovirus I, and Hepatitis-A virus and treated with gamma ray ionizing radiation from University of Lowell/DOE 800,000 Curie "6"0Co source over a dose range of 0.5--10 kiloGray (50--1000 kilorad) to determine the effectiveness of the process in eliminating viral activity and thus easing the potential viral health threats associated with uncooked bivalves. Two viral strains, SA-11 and Poliovirus I, were employed as models to perfect laboratory technique and to estimate the most appropriate range of dose exposures necessary for optimal inactivation of the infectious pathogen, Hepatitis A. Post-irradiation survivorship of the oysters and quahogs was ...
There is renewed interest in the +6 oxidation state of iron, ferrate (VI) (FeVIO42-), because of its potential as a benign oxidant for organic synthesis, as a chemical in developing cleaner ('greener') technology for remediation processes, and as an alternative for environment-friendly battery cathodes. This interest has led many researchers to focus their attention on the synthesis of ferrate(VI). Of the three synthesis methods, electrochemical, wet chemical and thermal, electrochemical synthesis has received the most attention due to its ease and the high purity of the product. Moreover, electrochemical processes use an electron as a so-called clean chemical, thus avoiding the use of any harmful chemicals to oxidize iron to the +6 oxidation state. This paper reviews the development of electrochemical methods to synthesize ferrate(VI). The approaches chosen by different laboratories to overcome some of the difficulties associated with the ...
Interest in renewable energy systems that employ regenerative components to enable intermittent energy sources to service time varying loads is growing. The overall performance of these systems is intimately linked to the choice of the energy storage media and the efficiency of the energy conversion devices. Recent advances in electrolyser and fuel cell technologies may make small-scale hydrogen buffered renewable energy systems a practical reality in the near term. A research team at the University of Victoria - Institute for Integrated Energy Systems (IESVic) is developing a flexible distributed, laboratory-scale energy system called IRENE (Integrated Renewable Energy Experiment). The initial goal of this research is to explore the potential for constructing a regenerative energy system using early commercial and precommercial hydrogen storage and fuel cell energy conversion devices. Once implemented, research efforts will focus on the ...
Metal contaminated crops from contaminated soils are possible hazards for the food chain. The aim of this study was to find practical and cost-effective measures to reduce metal uptake in crops grown on metal contaminated soils near a former metal smelter in Austria. Metal-inefficient cultivars of crop plants commonly grown in the area were investigated in combination with in-situ soil amendments. A laboratory batch experiment using 15 potential amendments was used to select 5 amendments to treat contaminated soil in a pot study using two Barley (Hordeum vulgare L.) cultivars that differed in their ability to accumulate cadmium. Results from this experiment identified 3 of these amendments for use in a field trial. In the pot experiment a reduction in ammonium nitrate extractable Cd (<41%) and Pb (<49%) compared to the controls was measured, with a concurrent reduction of uptake into barley grain (Cd < 62%, Pb < 68%). In the field ...
This Phase IV Remedial Design/Remedial Action Work Plan addresses the remediation of areas with the potential for UXO at the Idaho National Laboratory. These areas include portions of the Naval Proving Ground, the Arco High-Altitude Bombing Range, and the Twin Buttes Bombing Range. Five areas within the Naval Proving Ground that are known to contain UXO include the Naval Ordnance Disposal Area, the Mass Detonation Area, the Experimental Field Station, The Rail Car Explosion Area, and the Land Mine Fuze Burn Area. The Phase IV remedial action will be concentrated in these five areas. For other areas, such as the Arco High-Altitude Bombing Range and the Twin Buttes Bombing Range, ordnance has largely consisted of sand-filled practice bombs that do not pose an explosion risk. Ordnance encountered in these areas will be addressed under the Phase I Operations and Maintenance Plan that allows for the recovery and disposal of ordnance that poses an ...
In a scenario of aqueous transport from a high-level radioactive waste repository, the concentration of radionuclides in water in contact with the waste constitutes the source term for transport models, and as such represents a fundamental component of all performance assessment models. Many laboratory experiments have been done to characterize release rates and understand processes influencing radionuclide release rates from irradiated nuclear fuel. Natural analogues of these waste forms have been studied to obtain information regarding the long-term stability of potential waste forms in complex natural systems. This information from diverse sources must be brought together to develop and defend methods used to define source terms for performance assessment models. In this manuscript examples of measures of radionuclide release rates from spent nuclear fuel or analogues of nuclear fuel are presented. Each example represents a very different ...
The purpose and need for DOE to undertake the actions described in this document are to improve the efficiency of the Alternating Gradient Synchrotron (AGS) complex. Benefits would include optimization of the AGS scientific program, increased high-energy and nuclear physics experimentation, improved health and safety conditions for workers and users, reduced impact on the environment and the general public, energy conservation, decreased generation of hazardous and radioactive wastes, and completion of actions required to permit the AGS to be the injector to the Relativistic Heavy Ion Collider (RHIC)., Improved efficiency is defined as increasing the AGS`s capabilities to capture and accelerate the proton intensity transferred to the AGS from the AGS booster. Improved capture of beam intensity would reduce the beam losses which equate to lost scientific opportunity for study and increased potential for radiation doses to workers and the general public. The action ...
This report presents the results of the preliminary assessment (PA) conducted by Argonne National Laboratory at the Georgia Army National Guard (GAARNG) facility near Hinesville, Georgia, known as the National Guard Training Center (NGTC). Preliminary assessments of federal facilities are being conducted to compile the information necessary for completing preremedial activities and to provide a priority basis for completing corrective actions (where necessary) in response to releases of hazardous substances. The principal objective of the PA is to characterize the site accurately and determine the need for further action by examining previous site activities, types and quantities of hazardous substances utilized, and potential pathways by which contamination could affect public health and the environment. The scope of this assessment is limited to the facilities and past activities contained within the NGTC. Preliminary assessment site score ...
A permeable reactive mixture has been developed using low cost, readily available materials that is capable of providing effective, long-term phosphorous treatment in areas impacted by on-land wastewater disposal. The reactive mixture creates a geochemical environment suitable for P-attenuation by both adsorption and precipitation reactions. Potential benefits include significant reductions in phosphorous loading to receiving groundwater and surface water systems, and the accumulation of P-mass in a finite and accessible volume of material. The mixture may be applied as a component within surface treatment systems or in subsurface applications such as horizontal or vertical permeable reactive walls. The mixture averaged > 90% treatment efficiency over 3.6 years of continuous-flow laboratory column experiments. The mixture was further evaluated at the pilot-scale to treat municipal wastewater, and the field-scale to treat a well-characterized ...
The US Department of Energy is carrying out a program of research and development to establish the capability to produce synthetic liquid fuels from coal. According to the National Energy Policy Plan IV, the Assistant Secretary of Fossil Energy is charged with carrying out a program to foster an adequate supply of energy at reasonable cost through innovative, long-term R and D. The payoff for this kind of research is potentially high if the country should need the capability on short notice. However, the research is also high risk in terms of the expectation of process for synthetic fuels to turn a profit for a private sector company. As the date when commercial quantities of synfuels will be needed has retreated before lower real prices of petroleum, the US DOE program for coal liquefaction has evolved to give increasing support to longer range, more exploratory technologies, rather than those nearly developed to the point where commercialization is possible. ...
This report summarizes the work performed under the Sandia Laboratory Directed Research and Development (LDRD) project ``Optical Diagnostics for Turbulent and Multiphase Flows.`` Advanced optical diagnostics have been investigated and developed for flow field measurements, including capabilities for measurement in turbulent, multiphase, and heated flows. Particle Image Velocimetry (PIV) includes several techniques for measurement of instantaneous flow field velocities and associated turbulence quantities. Nonlinear photorefractive optical materials have been investigated for the possibility of measuring turbulence quantities (turbulent spectrum) more directly. The two-dimensional PIV techniques developed under this LDRD were shown to work well, and were compared with more traditional laser Doppler velocimetry (LDV). Three-dimensional PIV techniques were developed and tested, but due to several experimental difficulties were not as successful. The photorefractive ...
Pacific Northwest Laboratory (PNL) is investigating the use of a rock armoring blanket (riprap) to mitigate wind and water erosion of an earthen radon suppression cover applied to uranium mill tailings. Because the radon suppression cover and the tailings must remain intact for up to 1000 years or longer, the riprap must withstand natural weathering forces. This report is a review of information on rock weathering and riprap durability. Chemical and physical weathering processes, rock characteristics related to durability, climatic conditions affecting the degree and rate of weathering, and testing procedures used to measure weathering susceptibilities have been reviewed. Sampling and testing techniques, as well as analyses of physical and chemical weathering susceptibilities, are necessary to evaluate rock durability. Many potential riprap materials may not be able to survive 1000 years of weathering. Available techniques for durability ...
Logistics modeling is a powerful analytical technique for effective planning of waste storage, treatment, and disposal activities. Logistics modeling facilitates analyses of alternate scenarios for future waste flows, facility schedules, and processing or handling capacities. These analyses provide an increased understanding of the specific needs for waste storage, treatment, and disposal while adequate time remains to plan accordingly. They also help to determine the sensitivity of these needs to various system parameters. This paper discusses a logistics modeling system developed by the Pacific Northwest Laboratory (PNL) to aid in solid waste planning for a large industrial complex managing many different types and classifications of waste. The basic needs for such a system are outlined, and the approach adopted in developing the system is described. A key component of this approach is the development of a conceptual model that provides a flexible framework for ...
Xenotropic murine leukemia virus-related virus (XMRV) was discovered in human prostate tumors and later in some chronic fatigue syndrome (CFS) patients. However, subsequent studies have identified various sources of potential contamination with XMRV and other murine leukemia virus (MLV)-related sequences in test samples. Biological and nucleotide sequence analysis indicates that XMRV is distinct from known xenotropic MLVs and has a broad host range and cell tropism including human cells. Therefore, it is prudent to minimize the risk of human exposure to infection by evaluating XMRV contamination in cell lines handled in laboratory research and particularly those used in the manufacture of biological products. Nested DNA PCR assays were optimized for investigating XMRV gag and env sequences in various cell lines, which included MRC-5, Vero, HEK-293, MDCK, HeLa, and A549, that may be used in the development of some vaccines and other cell lines ...
A nuclear fuel waste disposal vault would not likely be a sterile environment. Bacterial activity would be expected in those areas of the vault conducive to bacterial life, i.e., where effects of heat, moisture content, radiation and compaction would not prevent or severely restrict bacterial life and where suitable and sufficient nutrients would be present. An inventory of bacterial nutrients that would be emplaced 'intentionally' with vault materials (fuel waste, waste containers, buffer and backfill materials) has been made previously. This report assesses bacterial nutrients that would be added 'inadvertently' to a vault in the form of residues of materials used to excavate and operate a vault. Measurements of blasting material residues in the various water supplies, excavated broken rock (muck) and in cores drilled in old and new tunnel walls were made at AECL's Underground Research Laboratory. Results show that the largest potential ...
Full text: The excessive use of chemical pesticides to control agricultural pests is becoming alarming. The objective of this study is to search for biopesticides of plant origin that could be used to control one of the major pest of fruit production; the Mediterranean fruit fly (Ceratitis capitata Wied.). A colony of the Lebanese wild strain of this insect was reared under laboratory condition to provide biological material. The insecticidal activity of the essential oils extracted from aromatic plants in Lebanon was assessed. The tested plants are: Foeniculum vulgare, Thymbra spicata, Artemisia herba alba, Origanum syriacum, Ruta chalepensis, Lavandula stoechas, Salvia fruticosa, Mentha microphylla, Juniperus oxycedrus, Rosmarinus officinalis, Myrtus communis, Laurus nobilis and Ocimum gratissimum. Results show that essential oils isolated from F. vulgare, T. spicata, A. herba alba, O. syriacum and R. chalepensis have promising insecticidal ...
This document describes the geology and hydrogeology at the former Advanced Coal Liquefaction Research and Development (ACLR&D) facility in Wilsonville, Alabama. The work was conducted by personnel from the Oak Ridge National Laboratory Grand Junction office (ORNL/GJ) for the U.S. Department of Energy (DOE) Pittsburgh Energy Technology Center (PETC). Characterization information was requested by PETC to provide baseline environmental information for use in evaluating needs and in subsequent decision-making for further actions associated with the closeout of facility operations. The hydrogeologic conceptual model presented in this report provides significant insight regarding the potential for contaminant migration from the ACLR&D facility and may be useful during other characterization work in the region. The ACLR&D facility is no longer operational and has been dismantled. The site was characterized in three phases: the first two ...
The objective of the current research in coal liquefaction is to produce a synthetic crude from coal at a cost lower than $30.00 per barrel (Task A). A second objective is to produce a fuel which is low in aromatics, yet of sufficiently high octane number for use in the gasoline-burning transportation vehicles of today. To meet this second objective, research was proposed for conversion of the highly-aromatic liquid product from coal conversion to a product high in isoparaffins, which compounds in the gasoline range exhibit a high octane number (Task B). Experimental coal liquefaction studies conducted in a batch microreactor in the laboratory have demonstrated potential for high conversions of coal to liquids with low yields of hydrocarbon (HC) gases, hence small consumption of hydrogen in the primary liquefaction step. Ratios of liquids/HC gases as high as 30/1, at liquid yields as high as 82% of the coal by weight, have been achieved. The ...
A test methodology for measuring temperature, impedance, pH, and electrochemical potential distributions within a sludge-packed tube support plate crevice in a laboratory test is described. The method successfully showed that there were large concentration gradients between the tube and tube support plate sides of the crevice. The testing also showed that strong bases concentrated more effectively than strong acids, and that the crevice pH, when exposed to seawater-based solutions, increased with increasing superheat and decreasing bulk concentration. The large variations in the crevice chemistry observed under heat transfer were eliminated upon shutdown. These new test data suggest that it might be beneficial to evaluate the variation in the extent of stress corrosion cracking with tube support plate elevation found in some steam generators in light of local chemistry changes, as well as the variation in tubing temperature. Because of the ...
The use of previously measured mixed-oxide (MOX) fuel systems as benchmarks can be valuable tool in computational analysis and quality assurance efforts. The Fissile Materials Disposition Program (FMDP) has identified these experiments as potential benchmarks, or standards, for VVER's employing MOX fuel. Standards for the analysis of these benchmark experiments were based on those used in the recent compilation International Handbook of Evaluated Criticality Safety Benchmark Experiments begun in 1992 by the U.S. Department of Energy. The Los Alamos National Laboratory's archives were explored for log-book records of these experiments without success. These experiments were the first to use MOX fuel in light water. Three approach-to-critical experiments were performed using fuel rods at various pitches and different plutonium-oxide concentrations. A parallel program verified the prediction of critical condition as similar materials and ...
A study was conducted under the auspices of the Coordinating Research Council, Inc. (CRC) to assess the potential effects of gasoline octane quality on vehicle acceleration performance. Twelve participating laboratories, representing both the oil and the automotive industries, tested a total of 182 vehicles as part of the 1989 CRC Octane Number Requirement Survey. The vehicles consisted of 78 with electronic knock control systems and 104 without. All testing was performed using the 1989/1990 CRC FBRU fuel series. The results showed that acceleration performance of vehicles with knock sensors was significantly affected by gasoline octane quality. Octane effects on acceleration performance were most pronounced at maximum-throttle (detent) conditions and at octane levels below the vehicles' octane requirements; however, some knock-sensor vehicles did show improved acceleration performance with fuels at octane levels above the octane ...
A program is currently in progress at Argonne National Laboratory to evaluate and develop evaporator technology for concentrating radioactive waste streams. By concentrating radioactive waste streams, disposal costs can be significantly reduced. To effectively reduce the volume of waste, the evaporator must achieve high decontamination factors so that the distillate is sufficiently free of radioactive material. One technology that shows a great deal of potential for this application is being developed by LICON, Inc. In this program, Argonne plans to apply LICON`s evaporator designs to the processing of radioactive solutions. Concepts that need to be incorporated into the design of the evaporator include, criticality safety, remote operation and maintenance, and materials of construction. To design an effective process for concentrating waste streams, both solubility and vapor-liquid equilibrium data are needed. The key issue, however, is the ...
One of the most promising battery types under development for use in both pure electric and hybrid electric vehicles is the lithium-ion battery. These batteries are well on their way to meeting the challenging technical goals that have been set for vehicle batteries. However, they are still far from achieving the current cost goals. The Center for Transportation Research at Argonne National Laboratory undertook a project for the US Department of Energy to estimate the costs of lithium-ion batteries and to project how these costs might change over time, with the aid of research and development. Cost reductions could be expected as the result of material substitution, economies of scale in production, design improvements, and/or development of new material supplies. The most significant contributions to costs are found to be associated with battery materials. For the pure electric vehicle, the battery cost exceeds the cost goal of the US Advanced Battery Consortium ...
Monitoring brine chemistry to determine the extent of potential adverse reactions has been simplified by the development of a field-brine test kit and a series of nomographs. Results of the kit analyses serve as input to the nomographs, which provide a graphic means of determining the scaling tendency (Saturation Index value) of a brine. Brines that do not tend to form scale may be corrosive. Saturation Index values were correlated with various processes using data from geopressured wells in the Gulf Coast area. Control of scale in surface equipment with chemical inhibitors has been successful. Numerous laboratory simulations of inhibitor squeeze operations were completed using core material with calcite present and absent. The corresponding wells were squeezed with phosphorous-containing inhibitors, and the flowback of brine was monitored for phosphorous concentrations vs time. A new procedure to measure the concentration of ...
The objective of this task was to obtain powder property data on candidate glass former materials, sufficient to guide conceptual design and estimate the cost of glass former handling facilities as requested under Part B1 of BNFL Technical and Development Support. Twenty-nine glass forming materials were selected and obtained from vendors for the characterization of their physical properties, durability in caustic solution, and powder flow characteristics. A glass former was selected based on the characterization for each of the ten oxide classes required for Envelope A, B, and C mixtures. Three blends (A, B, and C) were prepared based on formulations provided by Vitreous State Laboratory and evaluated with the same methods employed for the glass formers. The properties obtained are presented in a series of attached Tables. It was determined that five of the ten glass formers, (kyanite, iron oxide, titania, zircon, and zinc oxide) have the ...
Simultaneously extracted metals (SEM) and acid volatile sulfide (AVS) show the potential for toxicity on the basis of their ratio. Accordingly, the authors spiked cadmium in a range for which Cd/AVS ratios were from 0.2 to 10 in the sediment with its weight about 8 kg in each batch. Dialysis samplers with a cation ion-exchange resin (Dowex 50W-X4) collection were used in a laboratory for the determination of free cadmium concentrations in pore water of the collected sediment. When equilibrium was reached among cadmium in pore water, sediment, and ion-exchange resin, cadmium exchanged onto resin phase was regenerated with 1 N hydrochloric acid (OPTIMA grade) and determined using an atomic absorption spectrophotometer (Zeeman 5000) with a graphite furnace accessory. Cadmium determined using the dialysis sampler is considered as free cadmium which is related to the metal bioavailability toward aquatic biota. The developed methodology provides a ...
In recent years, there has been increased interest in using early life stages of freshwater bivalves to test the toxicity of dissolved constituents in water. The authors have developed laboratory and in situ assays with artificially cultured Utterbackia imbecillis to examine effects of contaminants and existing conditions in embayments and rivers on mortality and reproductive success of unionid mussels. Age sensitivity of U. imbecillis to Cd and Cu was examined using both static acute and 8-day static renewal bioassays. Both aqueous and sediment exposures demonstrated greater sensitivity to Cd than Cu. LC{sub 50}`s for two-day old (2d) and 9d mussels were approximately half the LC{sub 50} calculated for 16d mussels in 48-hr bioassays with Cd. Additionally, acute assays were repeated twice to examine variability in response between different mussel cultures to the two metals. The results of this work reinforce the potential of juvenile U. ...
This report addresses a Los Alamos National Laboratory (LANL) proposal to build a pulsed neutron source for simulating nuclear-weapons effects. A point design for the pulsed neutron facility was initiated early in FY94 after hosting a Defense Nuclear Agency (DNA) panel review and after subsequently visiting several potential clients and users. The technical and facility designs contained herein fulfill the Statement of Work (SOW) agreed upon by LANL and DNA. However, our point designs and parametric studies identify a unique, cost-effective, above-ground capability for neutron nuclear-weapons-effects studies at threat levels. This capability builds on existing capital installations and infrastructure at LANL. We believe that it is appropriate for us, together with the DNA, to return to the user community and ask for their comments and critiques. We also realize that the requirements of last year have changed significantly. Therefore, the ...
Three abiotic systems are described that catalyze the reductive dehalogenation of heavily halogenated environmental pollutants, including carbon tetrachloride, trichloroethene, and perchloroethene. These systems include (a) an electrolytic reactor in which the potential on the working electrode (cathode) is fixed by using a potentiostat, (b) a light-driven system consisting of a semiconductor and (covalently attached) macrocycle that can accept light transmitted via an optical fiber, and a light-driven, two-solvent (isopropanol/acetone) system that promotes dehalogenation reactions via an unknown mechanism. Each is capable of accelerating reductive dehalogenation reactions to very high rates under laboratory conditions. Typically, millimolar concentrations of aqueous-phase targets can be dehalogenated in minutes to hours. The description of each system includes the elements of reaction mechanism (to the extent known), typical kinetic data, and ...
In rare instances, carbon monoxide (CO) levels in houses can reach dangerously high concentrations, causing adverse health effects ranging from mild headaches to, under extreme conditions, death. Hundreds of fatal accidental carbon monoxide poisonings occur each year primarily due to the indoor operation of motor vehicles, the indoor use of charcoal for cooking, the operation of malfunctioning vented and unvented combustion appliances, and the misuse combustion appliances. Because there is a lack of simple, inexpensive, and accurate field sampling instrumentation, it is difficult for gas utilities and researchers to conduct field research studies designed to quantify the concentrations of CO in residences. Determining the concentration of CO in residences is the first step towards identifying the high risk appliances and high-CO environments which pose health risks. Thus, there exists an urgent need to develop and field-validate a CO-quantifying technique suitable for affordable field ...
Over the past 10 years, the Peruvian National Tuberculosis (TB) Program, the National Reference Laboratory (NRL), Socios en Salud, and US partners have worked to strengthen the national TB laboratory...Full Text Available
Coryneform isolates from clinical specimens frequently cannot be identified by either reference laboratories or research laboratories. Many of these organisms are skin flora that belong to a large number...Full Text Available
The U.S. Geological Survey, in cooperation with the U.S. Department of Energy, is conducting a study to determine the natural geochemistry of the Snake River Plain aquifer system at the Idaho National Engineering Laboratory (INEL), Idaho. As part of this study, a group of geochemical reactions that partially control the natural chemistry of ground water at the INEL were identified. Mineralogy of the aquifer matrix was determined using X-ray diffraction and thin-section analysis and theoretical stabilities of the minerals were used to identify potential solid-phase reactants and products of the reactions. The reactants and products that have an important contribution to the natural geochemistry include labradorite, olivine, pyroxene, smectite, calcite, ferric oxyhydroxide, and several silica phases. To further identify the reactions, analyses of 22 representative water samples from sites tapping the Snake River Plain aquifer system were used to ...
Protecting Earth and planets against the invasion of 'alien life forms' is not military science fiction, but it is the peaceful daily job of engineers and scientists of space agencies. 'Planetary Protection' is preventing microbial contamination of both the target planet and the Earth when sending robots on interplanetary space mission. It is important to preserve the 'natural' conditions of other planets and to not bring with robots 'earthly microbes' (forward contamination) when looking for 'spores of extra terrestrial life'. The Earth and its biosphere must be protected from potential extraterrestrial biological contamination when returning samples of other planets to the Earth (backward contamination). The NASA-Caltech Laboratory for Planetary Protection of Dr. Kasthuri Venkateswaran at the Jet Propulsion Laboratory (JPL) (California, USA) routinely monitors and characterizes the microbes of NASA spacecraft assembly ...
Project RPS116, ''Implementation of Boric Acid in the Field,'' was designed to demonstrate that a selected steam generator boric acid treatment is effective in arresting the progressing of denting in an operating steam generator. The PWR nuclear steam generators chosen for the testing were those at the Indian Point Unit 3 nuclear site. Hydrogen monitoring measurements and eddy current examinations had indicated that the Indian Point Unit 3, Series 44 steam generators had already reached an advanced stage of denting and tube support plate ligament discontinuities were observed. The objective of the boric acid treatment was to reduce the rate of denting by attempting to reproduce in the field the positive results achieved with boric acid in laboratory-simulated denting tests. Laboratory testing has indicated that implementation of a four day low power (25% power) boric acid soak with 50 ppm boron as boric acid followed by maintenance of a 5-10 ...
Plans for the disposal of radioactive liquid and solid wastes presently stored in double-shell tanks at the Hanford Site call for retrieval and processing of the waste to create forms suitable for permanent disposal. Waste will be retrieved from a tank using a submerged slurry pump in conjunction with one or more rotating slurry jet mixer pumps. Pacific Northwest Laboratory (PNL) has conducted tests using simulated waste slurries to assess the effects of a impinging slurry jet on the corrosion rate of the tank wall and floor, an action that could potentially compromise the tank's structural integrity. Corrosion processes were investigated on a laboratory scale with a simulated neutralized cladding removal waste (NCRW) slurry and in a subsequent test with simulated neutralized current acid waste (NCAW) slurry. The test slurries simulated the actual NCRW and NCAW both chemically and physically. The tests simulated ...
Plans for the disposal of radioactive liquid and solid wastes presently stored in double-shell tanks at the Hanford Site call for retrieval and processing of the waste to create forms suitable for permanent disposal. Waste will be retrieved from a tank using a submerged slurry pump in conjunction with one or more rotating slurry jet mixer pumps. Pacific Northwest Laboratory (PNL) has conducted tests using simulated waste slurries to assess the effects of a impinging slurry jet on the corrosion rate of the tank wall and floor, an action that could potentially compromise the tank`s structural integrity. Corrosion processes were investigated on a laboratory scale with a simulated neutralized cladding removal waste (NCRW) slurry and in a subsequent test with simulated neutralized current acid waste (NCAW) slurry. The test slurries simulated the actual NCRW and NCAW both chemically and physically. The tests simulated those ...
Corrosion characteristics of Al and Cu thin films have been studied in cyclic fog tests using tap water fog and fog created with 0.1% NaCl solution in tap water. Likewise, their corrosion features have been analyzed in continuous immersion testing in the laboratory in distilled water, tap water, in 0.1% NaCl and 3.5% NaCl solutions in distilled water. The corrosion potentials and the corrosion currents of these thin films change and reach steady state values after some time. However, steady state is not realized in 3.5% NaCl solutions. The corrosion current density data have been used to calculate lifetime of 1 {mu}m thick thin films of Al and Cu in the various tests, and assuming that the fog test data would hold under normal exposure conditions, life spans for these thin film sensor elements in actual exterior exposure have also been calculated. According to estimates, an Al-TF of about 1 {mu}m would last about 9 months in exterior exposure ...
The principles of modern pesticide residue chemistry were articulated in the 1950s. Early authors pointed out the advantages of systematizing and standardizing analytical methods for pesticides so that they could be widely practiced and the results could be reproduced from one laboratory to the next. The availability of improved methods has led to a much more complete understanding of pesticide behavior and fate in foods and the environment. Using methods based largely upon gas chromatography (GC) and high-performance liquid chromatography (HPLC) coupled increasingly with mass spectrometry (MS) and MS(n) as the detection tool, residues can be measured at parts per billion levels and below in a variety of food and environmental matrices. Development of efficient extraction and cleanup methods, techniques such as ELISA, efficient sample preparation techniques such as QuEChERS, and automated laboratory and field instrumentation has also ...
Feasibility of using combined release of sterile males and sterile females for population suppression of Earias vittella (Fabricius) was evaluated on okra in two ways. In one study, a combined release of sterile males and sterile females was evaluated under simulated conditions in laboratory, a 10: 10: 1: 1 (sterile male: sterile female: normal female: normal male) ratio effected > 99% sterility. In the second study, in a field cage experiment, a combined release of sterile males and sterile females was evaluated using normal males and tethered normal females. In this experiment, the release of sterile males and sterile females in 10: 10: 1: 1 ratio caused complete 'shut off' of mating of normal females for first 2 days and indicated>93% reduction in the larval progeny in the next generation. The tethered females were allowed to mate only once. E. vittella females mate multiply and so with overwhelming numbers of sterile males present, most probably the next ...
Ophir Corporation was awarded a contract by the U. S. Department of Energy, National Energy Technology Laboratory under the Project Title ''Airborne, Optical Remote Sensing of Methane and Ethane for Natural Gas Pipeline Leak Detection'' on October 14, 2002. This second six-month technical report summarizes the progress made towards defining, designing, and developing the hardware and software segments of the airborne, optical remote methane and ethane sensor. The most challenging task to date has been to identify a vendor capable of designing and developing a light source with the appropriate output wavelength and power. This report will document the work that has been done to identify design requirements, and potential vendors for the light source. Significant progress has also been made in characterizing the amount of light return available from a remote target at various distances from the light source. A ...
Oregon State University (OSU) and the Pacific Northwest National Laboratory (PNNL) were funded by the U.S. Department of Energy to conduct research focused on resolving the key technical issues that limited the deployment of efficient and extremely compact microtechnology based heat actuated absorption heat pumps and gas absorbers. Success in demonstrating these technologies will reduce the main barriers to the deployment of a technology that can significantly reduce energy consumption in the building, automotive and industrial sectors while providing a technology that can improve our ability to sequester CO{sub 2}. The proposed research cost $939,477. $539,477 of the proposed amount funded research conducted at OSU while the balance ($400,000) was used at PNNL. The project lasted 42 months and started in April 2001. Recent developments at the Pacific Northwest National Laboratory and Oregon State University suggest that the performance of ...
There is increasing pressure to operate laboratory facilities in environmentally and financially sustainable ways. A key factor in achieving this goal is careful consideration of how energy is used by the buildings' ventilation system, both for conditioning air supplied to the laboratories and the energy used moving air through the building. Traditionally, laboratory energy use is treated as an engineering concern within the scope of the building's overall design and operation. However, this approach limits the involvement of key stakeholders in many important decisions and can lead to unexpected safety concerns for the laboratory's users. We believe that a broad view of the parties affected by a laboratory building's operations is necessary to avoid having the various stakeholders working...
BackgroundDuplications of stretches of the genome are an important source of individual genetic variation, but their unrecognized presence in laboratory organisms would be a confounding...Full Text Available
as manufacturing plants and laboratories, including the Chemical Laboratory at the House of David in Benton Harbor, Michigan. Built in America: Historic Building Buildings Survey/...
as one of the first Materials Research Laboratories to be funded by the forerunner of DARPA. In 1972 funding was taken over by the National Science Foundation's Division of...
The purpose of this statement of work (SOW) is to establish laboratory analytical criteria and requirements for radioactive airborne emissions measurement sample and/or analysis activities.
This document details monthly activities at the Savannah River Laboratory. Topics addressed are reactor operation; tritium facilities and production; separation operations; environmental concerns; and waste management. (FI)
This document details monthly activities at the Savannah River Laboratory. Topics addressed are reactor operation; tritium facilities and production; separation operations; environmental concerns; and waste management. (FI)
Oct 30, 2006 ... Pigment Analysis by HPLC at Horn Point Laboratory. Laurie Van Heukelem. Crystal Thomas. Meg Maddox. University of Maryland Center for ...
Publications Science Highlights Researcher Profiles Internship Funding to push battery technology from Argonne Laboratory to marketplace Bookmark and Share (Download...
This report summarizes the research conducted during Budget Period One on the project ''Improved Natural Gas Storage Well Remediation''. The project team consisted of Furness-Newburge, Inc., the technology developer; TechSavants, Inc., the technology validator; and Nicor Technologies, Inc., the technology user. The overall objectives for the project were: (1) To develop, fabricate and test prototype laboratory devices using sonication and underwater plasma to remove scale from natural gas storage well piping and perforations; (2) To modify the laboratory devices into units capable of being used downhole; (3) To test the capability of the downhole units to remove scale in an observation well at a natural gas storage field; (4) To modify (if necessary) and field harden the units and then test the units in two pressurized injection/withdrawal gas storage wells; and (5) To prepare the project's final ...
Lateral and vertical variabilities in the bulk and mechanical properties of silicic volcanic tuff at the potential nuclear waste repository site in Yucca Mountain, NV have been evaluated. Laboratory measurements have been performed on tuff specimens recovered from boreholes located to support the design of the Exploratory Studies Facility/North Ramp. The data include dry and saturated bulk densities, average grain density, porosity, compressional and shear wave velocities, elastic moduli, and compressional and tensional fracture strengths. Data from eight boreholes aligned in a northwest-southeast direction have been collected under the required quality assurance program. Three boreholes have penetrated the potential repository horizon. The information collected provides for an accurate appraisal of the variability of rock properties in the vicinity of the boreholes. As expected, there is substantial variability in the bulk ...
Analytical means have been developed to predict scour and accretion in sub-sea structures. Such structures can be very large and can have a large density of piping and structural members. They introduce a blocking and a shielding in the flow at the sea bottom leading to variable velocities and turbulence in the interior of the structure. This changes the transport capacity of the flow and result in general erosion where the transport capacity is increased and in accretion where the transport capacity is decreased. In addition there may occur the so-called tunnel erosion for structures built on concrete mats or similar. This type of erosion undermines the foundation of the sub-sea structure. Analytical models are developed and programmed to analyse the above phenomena. The internal flow variations are found by means of the LICengineering shielding programme and these are coupled to the transport formulae. The methodology is unstable if the starting conditions are too far away from the ...
Since the Scientific Assessment of Ozone Depletion: 1998, numerous laboratory investigations, atmospheric observations, and theoretical and modeling studies have produced new key findings and have strengthened overall understanding of the ozone layer and its effect on ultraviolet (UV) radiation. These advances are highlighted in the following summary of the current understanding of the impact of human activities and natural phenomena on the ozone layer and the coupling of the ozone layer and the climate system. In the troposphere (i.e., lower atmosphere), observations show that the total combined effective abundance of ozone-depleting compounds continues to decline slowly from the peak that occurred in 1992-1994. Total chlorine is declining, while bromine from industrial halons is still increasing, albeit at a slower rate than was occurring previously (and as reported in the 1998 Assessment). Analyses of air trapped in snow since the late 19th century have ...
Prompted by a $10 million Congressional allocation to identify supplemental actions to protect the Columbia River from groundwater contamination beneath the Hanford Reservation, the U. S. Department of Energy (DOE) Environmental Management (EM) Office of Clean-up Technology identified twenty-three potential technical projects and then down-selected ten of these for further evaluation. An independent expert peer review was conducted for the ten down-selected proposals. The review panel consisted of twenty-three recognized subject matter experts that broadly represented academia, industry, and federal laboratories. Of the initial ten proposals reviewed, one was given unconditional support, six were given conditional support, and three were not supported as proposed. Three additional proposals were then submitted by DOE for review--these proposals were structured, in part, to respond to the initial round of technical peer review comments. Peer ...
A preliminary geologic investigation was conducted to determine if Triassic sedimentary rocks of the Sanford basin and Colon cross structure in North Carolina are favorable hosts for uranium deposits. Rocks of adjacent Carolina slate belt were also examined as a potential source of uranium. On the basis of favorability criteria for sandstone-type uranium deposits, and geologic and geophysical investigations of the study area, the most favorable sites for further investigation are (1) at the contacts between the Pekin and Cumnock and between the Pekin and Sanford Formations near the Colon cross structure and (2) at the base of the Jonesboro fault, which lies below the Sanford Formation, northwest of Sanford. The highly weathered granites southeast of the Jonesboro fault were a source of the detritus deposited on the cross structure and may have been a primary source of uranium. Uranium leached from the coarse sediment (Pekin Formation) of the cross structure may ...
The coalbed methane (CBM) geology, resource and production potential in the Weibei Coalfield, southeastern Ordos Basin are studied based on geological surveys and laboratory measurements. The results showed that coal rank varies both laterally and vertically and changes from volatile bituminous coals in the margin to anthracites towards the basin (1.6-2.5% R{sub o}). Coals are composed of 60-85% vitrinite, 15-40% inertinite and a trace amount of minerals. Methane isothermal adsorption measurements of 20 coal samples revealed that the maximum adsorption capacity (on a dry and ash-free basis) of coals, which are affected by coal rank, coal maceral, coal lithotype and especially to the moisture content, varies from 13.91 to 29.54 m{sup 3}/t. Estimated gas contents range from 0 to 15 m{sup 3}/t. These data yield an estimated in-place CBM resource of 2.5 x 10{sup 11} m{sup 3} for the Weibei Coalfield. In combination with the geological information, ...
Amoco Trinidad Oil Company produces 60,000 bbl/d of oil from the Trinidadian offshore. The oil is pipelined ashore where it is processed and returned offshore to a buoy mooring for transport up Trinidad's east coast. Amoco Trinidad has developed comprehensive oil spill contingency plans, starting from computer models of spill scenarios. The models used initially assumed that the oils would emulsify quickly and the spills would become highly viscous and persistent, reaching the shoreline in 15-24 h. Such behavior would render ineffective the use of dispersants as a spill countermeasure. Studies showed a poor potential capability of physical recovery systems for spills off the Trinidad east coast due to high sea states, strong winds, and other factors. These results led to questioning of the spill model's assumptions, and laboratory tests were conducted to study the actual behavior of the crude oils. It was found that the oil was difficult to ...
This document presents a conceptual design for a contingency interim measure (IM) for treatment of the public water supply system at Barnes, Kansas, should this become necessary. The aquifer that serves the public water supply system at Barnes has been affected by trace to low concentrations of carbon tetrachloride and its degradation product, chloroform. Investigations conducted on behalf of the CCC/USDA by Argonne National Laboratory (Argonne 2008a) have demonstrated that groundwater at the Barnes site is contaminated with carbon tetrachloride at concentrations exceeding the Kansas Tier 2 risk-based screening level (RBSL) and the EPA maximum contaminant level (MCL) of 5.0 {micro}g/L for this compound. The Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) formerly operated a grain storage facility in Barnes, approximately 800 ft east-southeast of the public water supply wells. Carbon tetrachloride was used in the treatment of grain. ...
The traditional process for developing large-scale simulations is cumbersome, time consuming, costly, and in some cases, inadequate. The topics of software components and component-based software engineering are being explored by software professionals in academic and industrial settings. A component is a well-delineated, relatively independent, and replaceable part of a software system that performs a specific function. Many researchers have addressed the potential to derive a component-based approach to simulations in general, and a few have focused on military simulations in particular. In a component-based approach, functional or logical blocks of the simulation entities are represented as coherent collections of components satisfying explicitly defined interface requirements. A simulation is a top-level aggregate comprised of a collection of components that interact with each other in the context of a simulated environment. A component may represent a ...
There is a continuing need to understand dose-response relationships for ionizing radiation in order to protect the health of the public and nuclear workers from undue exposures. However, relatively few human populations have been exposed to doses of radiation high enough to cause observable, long-term health effects from which to derive dose-response relationships. This is particularly true for internally deposited radionuclides, although much effort has been devoted to epidemiological studies of the few types of exposures available, including lung cancers in uranium miners form the inhalation of the radioactive decay products of Ra, liver cancers in patients injected with Thorotrast X-ray contrast medium containing Th, bone cancers in radium dial painters who ingested Ra, and bone cancers in patients who received therapeutic doses of Ra. These four types of exposures to internally deposited radionuclides provide a basis for understanding the health effects of many other radionuclides ...
This research is to provide improved strategies for enhanced oil recovery from the Tensleep Sandstone oil reservoirs in the Bighorn and Wind River basins, Wyoming. Because of the great range of API gravities of the oils produced from these reservoirs, the proposed study concentrates on understanding the spatial variation and anisotropy of relative permeability within the Tensleep Sandstone. This research will associate those spatial distributions and anisotropies with the depositional subfacies and zones of diagenetic alteration found within the sandstone. The associations of the above with pore geometry will link relative permeability with the dimensions of lithofacies and authigenic mineral facies. Hence, the study is to provide criteria for scaling this parameter on a range of scales, from the laboratory to the basin-wide scale of subfacies distribution. Effects of depositional processes and burial diagenesis will be investigated. Image analysis of pore systems ...
Carbon monoxide can be produced in severe accidents from interaction of ex-vessel molten core with concrete. Depending on the particular core-melt scenario, the type of concrete and geometric factors affecting the interaction, the quantities of carbon monoxide produced can vary widely, up to several volume percent in the containment. Carbon monoxide is a combustible gas. The carbon monoxide thus produced is in addition to the hydrogen produced by metal-water reactions and by radiolysis, and represents a possibly significant contribution to the combustible gas inventory in the containment. Assessment of possible accident loads to containment thus requires knowledge of the combustion properties of both CO and H_2 in the containment atmosphere. Extensive studies have been carried out and are still continuing in the nuclear industry to assess the threat of hydrogen in a severe reactor accident. However the contribution of carbon monoxide to the combustion threat has received less ...
The Jewish philosopher and educator Martin Buber (1878-1965) is considered one of the twentieth century's greatest contributors to the philosophy of religion and is also recognized as the pre-eminent scholar of Hasidism. He has also attracted considerable attention as a philosopher of education. However, most commentaries on this aspect of his work have focussed on the implications of his philosophy for formal education and for the education of the child. Given that much of Buber's philosophy is based on dialogue, on community and on mutuality, it is puzzling that relatively little has been written on the implications of Buber's thought for the theory and practice of non-formal adult education. The article provides a discussion of the philosophy underpinning this aspect of Martin Buber's l...
The last decade has produced an explosion in neuroscience research examining young children's early processing of language that has implications for education. Noninvasive, safe functional brain measurements have now been proven feasible for use with children starting at birth. In the arena of language, the neural signatures of learning can be documented at a remarkably early point in development, and these early measures predict performance in children's language and pre-reading abilities in the second, third, and fifth year of life, a finding with theoretical and educational import. There is evidence that children's early mastery of language requires learning in a social context, and this finding also has important implications for education. Evidence relating socioeconomic status (SES) ...
The most striking achievement in magnetic fusion experiments during last few years was the discovery of plasma detachment from material targets, a much needed effect for plasmas with high power fusion parameters. Due to the very low heat loads on the targets observed in these regimes and potentially low erosion of the targets, detached regimes look attractive from the International Thermonuclear Experimental Reactor (ITER) design point of view. Thus the author has experimental proof for the possibility for a co-existence of fusion relevant hot plasma in the core and a low temperature partly ionized plasma at the edge of magnetic fusion device. Although somewhat similar behavior of edge plasma was considered theoretically even before plasma detachment was found experimentally, it was not clear in the beginning how these theoretical and experimental findings would fit together. Now, after a few years of intensive additional experimental and theoretical studies, a ...
BackgroundPolicies on waste disposal in Europe are heterogeneous and rapidly changing, with potential health implications that are largely unknown. We conducted a health impact assessment of landfilling and incineration in three European countries: Italy, Slovakia and England.MethodsA total of 49 (Italy), 2 (Slovakia), and 11 (England) incinerators were operating in 2001 while for landfills the figures were 619, 121 and 232, respectively. The study population consisted of residents living within 3 km of an incinerator and 2 km of a landfill. Excess risk estimates from epidemiological studies were used, combined with air pollution dispersion modelling for particulate matter (PM10) and nitrogen dioxide (NO2). For incinerators, we estimated attributable cancer incidence and years of life lost (YoLL), while for landfills we estimated attributable cases of congenital anomalies and low birth weight infants.ResultsAbout 1,000,000, 16,000, and ...
Total EU (and Norway) emissions of CO_2 from thermal power generation were some 950 million tonnes in 1990, the Kyoto agreement reference level. An ongoing research project, the GESTCO project, will provide the first documentation that, for the emission sources within the selected key areas, sufficient geological storage capacity is available for at least 30 years and possibly much longer. Cost of energy will obviously increase, but it is anticipated that electricity production cost price will be comparable to that of renewables. It would further have major implications for the European power generating industry which today is totally dominated by fossil fuel combustion with enormous emissions problems. The identification and siting of subsurface CO_2 storage capability can be expected to have considerable effect on the planning for and future siting of fossil fuel plants. In Norway there are plans to build several major, coastally sited, natural gas-fed ...
The Oak Ridge National Laboratory (ORNL) is a multiprogram, multipurpose laboratory that conducts research in the physical, chemical, and life sciences; in fusion, fission, and fossil energy; and in energy conservation and other energy-related technologies. This review outlines some current endeavors of the lab. A state of the laboratory presentation is given by director, Alvin Trivelpiece. Research of single crystals for welding is described. The Science Alliance, a partnership between ORNL and the University of Tennessee, is chronicled. And several incites into distinguished personnel at the laboratory are given. (GHH)
To encourage the application of robotics technology for routine radiobench applications, a laboratory dedicated to the research and development of contained robotic systems is being constructed. The facility will have several robots located in laminar flow hoods, and the hoods are being designed to allow the possibility for multiple robots to work together. This paper presents both the design features of the hoods and the general layout of the laboratory, and also discusses an application of a robotic system for the routine nuclear counting of gamma tube samples. The gamma tube system is presently operating in one of the routine analysis laboratories. 5 figs.
The phosphatidylinositol pathway is implicated in the regulation of numerous cellular functions and responses to extracellular signals. An important branching point in the pathway is the phosphorylation...Full Text Available
The side effects of cancer therapy on normal tissues limit the success of therapy. Generation of reactive oxygen species (ROS) has been implicated for numerous chemotherapeutic agents including doxorubicin...Full Text Available
To date few reports have provided direct comparison of psychosocial vulnerability and resources among youth with victimization and perpetration histories. Within a racially diverse, high-risk...Full Text Available
Objective To establish current practice in the use of Read codes for diabetes.Design Cross sectional study.Setting 17 practices in the Battersea...Full Text Available
BackgroundProlylcarboxypeptidase (Prcp) gene, along with altered PRCP and kallikrein levels, have been implicated in inflammation pathogenesis. PRCP regulates angiotensin...Full Text Available
In a "nutrition transition", the consumption of foods high in fats and sweeteners is increasing throughout the developing world. The transition, implicated in the rapid rise of obesity and diet-related...Full Text Available
I report on some recent work done in collaboration with E. de Rafael on the connection between ultraviolet renormalons in QCD and Nambu-Jona-Lasinio-like Lagrangians as its effective description at low energies. (orig.)
In addition to the well documented role of cytokines in mediating tissue-level interactions, it is now clear that matrix macromolecules fulfil a complementary regulatory function. Data highlighted in...Full Text Available
Recent research has implicated the nucleus accumbens (NAc) in consolidating recently acquired goal-directed appetitive memories, including spatial learning and other instrumental processes. However,...Full Text Available
Memory consolidation requires transcription and translation of new protein. Arc, an effector immediate early gene, and zif268, a regulatory transcription factor, have been implicated in synaptic plasticity...Full Text Available
PurposeHeavy metals and other forms of oxidative stress have been implicated as key factors in the formation of age-related cataract in humans. Metallothioneins are...Full Text Available
Krabbe disease (KD) is an inherited neurological disorder caused by the deficiency of galactocerebrosidase activity resulting in accumulation of psychosine, which leads to energy depletion,...Full Text Available
Mouse genetic resources include inbred strains, recombinant inbred lines, chromosome substitution strains, heterogeneous stocks, and the Collaborative Cross (CC). These resources were generated through...Full Text Available
Peri-prosthetic infections are notoriously difficult to treat as the biomaterial implant is ideal for bacterial adhesion and biofilm formation, resulting in decreased antibiotic sensitivity....Full Text Available
The target of rapamycin (TOR) pathway regulates cell growth and aging in various organisms. In Saccharomyces cerevisiae, silent information regulator 2 (Sir2) modulates cellular senescence. Moreover,...Full Text Available
DNA methylation of cytosine residues is a widespread phenomenon and has been implicated in a number of biological processes in both prokaryotes and eukaryotes. This methylation occurs at the 5-position...Full Text Available
What do we mean when we say that a mental condition is a medical disorder rather than a normal form of human suffering or a problem in living? The status of psychiatry as a medical discipline depends...Full Text Available
Paraquat poisoning in mammals results in a characteristic lung lesion manifested principally as progressive pulmonary fibrosis. Paraquat is actively concentrated into the lung but the site of uptake remains undefined. A method is described for the autoradiographic localization of paraquat in rats. Preliminary evidence for the site of uptake implicates the bronchiol. (author).
Anthocyanins are flavonoid pigments that accumulate in the large central vacuole of most plants. Inside the vacuole, anthocyanins can be found uniformly distributed or as part of sub-vacuolar pigment...Full Text Available
The fungal pathogen Candida albicans is one of the leading causative agents of death in immunocompromised individuals. It harbors an arsenal of cell wall anchored factors that are implicated...Full Text Available
Cilia are important cellular structures that have been implicated in a variety of signaling cascades. In this review, we discuss the current evidence for and against a link between cilia and both the...Full Text Available
The proliferation of stem cell research, conflated with its ethical and moral implications, has led governments to attempt regulation of both the science and funding of stem cells. Due to a diversity...Full Text Available
Comparative studies of flocculent and grand-design spirals suggest that density waves are not the predominant trigger of star formation in most galaxies. Implications for chemical evolution are profound. It may be possible to ignore the details of the spiral-wave phenomenon in research aimed at unifying the chemical properties of spiral disks. 16 references.
The length polymorphism of the serotonin (5-HT) transporter gene promoter region has been implicated in altered 5-HT function and, in turn, neuropsychiatric illnesses, such as anxiety and depression....Full Text Available
BackgroundUnderstanding the interactions between ion channels and blockers remains an important goal that has implications for delineating the basic mechanisms of ion channel function...Full Text Available
Destress blasting is commonly used as a stress control technique at the Galena Mine, Wallace, Idaho, where the U.S. Bureau of Mines maintains a cooperative research program with the mine operators (ASARCO). A digital seismic array and an array of borehole...
BackgroundMagnetic Resonance Imaging scanners have become ubiquitous in hospitals and high-field systems (greater than 3 Tesla) are becoming increasingly common. In light of recent...Full Text Available
A vast amount of circumstantial evidence implicates oxygen-derived free radicals (especially, superoxide and hydroxyl radical) and high-energy oxidants [such as peroxynitrite (OONO−)]...Full Text Available
The etiology of major depression remains unknown, but dysfunction of serotonergic signaling has long been implicated in the pathophysiology of this disorder. p11 is an S100 family member recently...Full Text Available
BackgroundSynonymous sites are freer to vary because of redundancy in genetic code. Messenger RNA secondary structure restricts this freedom, as revealed by previous findings in...Full Text Available
That regulatory T cells (Tregs) have a crucial role in controlling allergic diseases such as asthma is now undisputed. The cytokines most commonly implicated in Treg-mediated suppression of...Full Text Available
RasGRF1 is a Ras-guanine nucleotide exchange factor implicated in a variety of physiological processes including learning and memory and glucose homeostasis. To determine the role of RASGRF1 in aging,...Full Text Available
A pore-forming peptide is implicated in the potent cytolytic activity of pathogenic Entamoeba histolytica. Using NH2-terminal sequence information of this peptide, the corresponding cDNA was isolated....Full Text Available
Preterm and low birthweight (PTLBW) continues to be a major cause of mortality and morbidity across the world. In recent years, maternal periodontal disease has been implicated as a risk factor for...Full Text Available
Human longevity is in part genetically determined, and the insulin/IGF-1 signal transduction (IIS) pathway has consistently been implicated. In humans, type 2 diabetes is a frequent disease that results...Full Text Available
To resolve the phylogeny of the autochthonous mitochondrial DNA (mtDNA) haplogroups of India and determine the relationship between the Indian and western Eurasian mtDNA pools more precisely, a diverse...Full Text Available
OBJECTIVENicotinamide adenine dinucleotides (NAD+ and NADH) play a crucial role in cellular energy metabolism, and a dysregulated NAD+-to-NADH ratio is implicated...Full Text Available
... be rare or absent as leaves in the forest litter. The differences between the amount of leaf and ... the relative proportions of leaf species in a forest litter when compared with standing biomass has sig...
The nucleocapsid protein (NC) of retroviruses plays a major role in genomic RNA packaging, and some evidence has implicated the matrix protein (MA) of certain retroviruses in viral RNA binding. To further...Full Text Available
Neutral endopeptidase 24.11 (NEP, CD10) is a cell-surface enzyme expressed by prostatic epithelial cells that cleaves and inactivates neuropeptides implicated in the growth of androgen-independent prostate...Full Text Available
Myelin-associated glycoprotein (MAG) has been implicated in inhibition of nerve regeneration in the CNS. This results from interactions between MAG and the Nogo receptor and gangliosides on...Full Text Available
BackgroundThe precise mechanisms involved in the initiation and progression of rheumatoid arthritis (RA) are not known. Early stages of RA often have non-specific symptoms, delaying...Full Text Available
The discussion of energy usage falls naturally into three parts. The first is a review of what the problem is, the second is a description of steps that can be taken to conserve energy at existing facilities, and the third is a review of the implications of energy consumption on future facilities.
Antibodies to myelin oligodendrocyte glycoprotein (MOG) have been implicated in Multiple Sclerosis demyelination through activation of complement and/or macrophage-effector processes. We presented...Full Text Available
There has been great interest in understanding the methods by which collagen-based load-bearing tissue is constructed, grown and maintained in vertebrate animals. To date, the responsibility for this...Full Text Available
Electricity markets in the United States are undergoing unprecedented structural changes as a result of the confluence of regulatory, competitive, and technological forces. This paper introduces these structural changes and forces and discuss the implications, markets and commercialization scenarios for emerging fuel cells in evolving US electricity markets.
Over the last two centuries, there has been a significant increase in average lifespan expectancy in the developed world. One unambiguous clinical implication of getting older is the risk of experiencing...Full Text Available
... on a transgressive surface; examples from the Silurian Whirlpool Sandstone of southern Ontario, Canada. Journal of Sedimentary ... and C. J. Salas. 1991. The Lower Silurian Whirlpool Sandstone. in Cheel, ...
To determine the mechanism of the cardiac dilatation and reduced contractility of obese Zucker Diabetic Fatty rats, myocardial triacylglycerol (TG) was assayed chemically and morphologically. TG was...Full Text Available
Decitabine, an epigenetic modifier that reactivates genes otherwise suppressed by DNA promoter methylation, is effective for some, but not all cancer patients, especially those with solid tumors. It...Full Text Available
The receptors for IGF-I (IGF-IR) and insulin (IR) have been implicated in physiological cardiac growth, but it is unknown whether IGF-IR or IR signaling are critically required. We generated mice with...Full Text Available
Stargardt disease (STGD) is the major form of inherited juvenile macular degeneration. Pyridinium bis-retinoid A2E is a major component of lipofuscin which accumulates in retinal pigment epithelium...Full Text Available
BackgroundApproximately 80% of all new HIV-1 infections are acquired through sexual contact. Currently, there is no clinically approved microbicide, indicating a clear and...Full Text Available
Oxidative stress has been implicated in the etiology of age-related muscle loss (sarcopenia). However, the underlying mechanisms by which oxidative stress contributes to sarcopenia have not been thoroughly...Full Text Available
Infections have been implicated in the pathogenesis of a number of autoimmune diseases, and Yersinia enterocolitica (YE) might play a role in the development of autoimmune thyroid disease...Full Text Available
Sauropod dinosaurs, the dominant herbivores throughout the Jurassic, challenge general rules of large vertebrate herbivory. With body weights surpassing those of any other megaherbivore, they relied...Full Text Available
Records of past climates contained in ice cores, ocean sediments, and other archives show that large, abrupt, widespread climate changes have occurred repeatedly in the past. These changes were especially...Full Text Available
IntroductionPrevious observations suggest that active systemic juvenile idiopathic arthritis (sJIA) is associated with a prominent erythropoiesis gene-expression signature. The aim...Full Text Available
Illthrift was observed in 20/60 lambs aged 40–45 days in a dairy sheep flock in Greece. Cryptosporidiosis had been diagnosed and successfully treated with halofuginone lactate a month earlier....Full Text Available
The hyaluronic acid capsule of Streptococcus uberis has been implicated in conferring resistance to phagocytosis by bovine neutrophils. Construction of a bank of random insertion mutants...Full Text Available
Objectives. Thousands of Louisiana residents were asked to boil water because of widespread disruptions in electricity and natural gas services after Hurricane Rita. We sought to assess...Full Text Available
The content of guanine+cytosine varies markedly along the chromosomes of homeotherms and great effort has been devoted to studying this heterogeneity and its biological implications. Already...Full Text Available
Childhood cancer survivors often experience complications related to cancer and its treatment that may adversely affect quality of life and increase the risk of premature death. The purpose of this...Full Text Available
BackgroundHuman Papillomavirus (HPV) E2 plays several important roles in the viral cycle, including the transcriptional regulation of the oncogenes E6 and E7, the regulation of the...Full Text Available
Neonatal administration of the synthetic glucocorticoid, dexamethasone (DEX) retards brain growth, alters adult behaviors and induces cell death in the rat brain, thereby implicating glucocorticoids...Full Text Available
The continued evolution of bacterial pathogens has major implications for both human and animal disease, but the exchange of genetic material between host-restricted pathogens is rarely considered....Full Text Available
BackgroundEpidemiological studies showed that physical exercise, specifically moderate lifelong training, is protective against cardiovascular morbidity and mortality. Most experimental...Full Text Available
Free radical formation has been implicated in the toxicity of a wide range of xenobiotics. In recent years, particular interest has been paid to compounds which can undergo a one electron reduction...Full Text Available
BackgroundLeukotrienes (LTs) belong to the large family of lipid mediators implicated in various inflammatory conditions such as asthma and rheumatoid arthritis. Four distinct types...Full Text Available
Bisretinoid lipofuscin compounds that accumulate in retinal pigment epithelial (RPE) cells are implicated in the pathogenesis of some forms of macular degeneration. In the development of approaches...Full Text Available
BackgroundObesity has reached epidemic proportions in the United States. It is implicated in the development of a variety of chronic disease states and is associated with increased...Full Text Available
Neurons containing the neuropeptide hypocretin (orexin) are localized only in the lateral hypothalamus from where they innervate multiple regions implicated in arousal, including the basal forebrain....Full Text Available
Purpose.To determine the effects of vasodilators on intraocular pressure (IOP) and the protein content of sheep aqueous humor (AH), because the vasodilators may increase fluid leakage...Full Text Available
Porphyromonas gingivalis has been implicated as a causative pathogen in periodontitis. Immunotherapeutic approaches have recently been suggested to aid in the clearance of P....Full Text Available
Molecular life science is one of the fastest-growing fields of scientific and technical innovation, and biotechnology has profound effects on many aspects of daily life—often with deep, ethical...Full Text Available
The sirtuin Sirt6 is a NAD-dependent histone deacetylase that is implicated in gene regulation and lifespan control. Sirt6 can interact with the stress-responsive transcription factor NF-κB...Full Text Available
Merozoite surface proteins have been implicated in the initial attachment to the host red blood cell membrane that begins the process of invasion, an important step in the life cycle of the malaria...Full Text Available
The worldwide decline in honeybee colonies during the past 50 years has often been linked to the spread of the parasitic mite Varroa destructor and its interaction with certain honeybee...Full Text Available
Circadian clock is implicated in the regulation of aging. The transcription factor CLOCK, a core component of the circadian system, operates in complex with another circadian clock protein BMAL1. Recently...Full Text Available
Details of ion transporting abnormalities in cystic fibrosis airway epithelium are now known. The central hypothesis, that excessive drying of the airway surfaces is a primary event that leads to all...Full Text Available
Magnetotactic bacteria contain chains of magnetically interacting crystals (magnetosome crystals), which they use for navigation (magnetotaxis). To improve magnetotaxis efficiency, the magnetosome crystals...Full Text Available
Since polyglutamine (polyQ) aggregate formation has been implicated as playing an important role in expanded CAG repeat diseases, it is important to understand the biophysics underlying the...Full Text Available
Communication problems have been implicated in many safety and quality issues, but tools to examine communication networks and their impact on patient outcomes are only beginning to become available....Full Text Available
Objective: Hamstring injuries can be quite debilitating and often result in chronic problems. Eccentric muscle actions are often the last line of defense against muscle injury...Full Text Available
MicroRNAs (miRNAs) have been implicated to play key roles in normal physiological functions, and altered expression of specific miRNAs has been associated with a number of diseases. It is of great interest...Full Text Available
Our understanding of the development of neurotransmitter systems in the central nervous system has increased greatly over the past three decades and it has become apparent that drug effects...Full Text Available
The purpose of this study was to determine the clinical significance of nodal micrometastasis detected by immunohistochemistry in patients that had undergone curative surgery for pancreatic cancer....Full Text Available
BackgroundMultiple sclerosis (MS) is the endpoint of a complex and still poorly understood process which results in inflammation, demyelination and axonal and neuronal degeneration....Full Text Available
Urethral and endocervical swabs and self-collected vaginal swabs (SCVSs) and urine specimens are all used as samples for diagnosis of urogenital infection with Chlamydia trachomatis....Full Text Available
Approximately 20% to 30% of patients who undergo coronary arteriography for the evaluation of chest pain are found to have normal coronary arteries. These patients have a survival rate comparable to...Full Text Available
The synthesis of an extracellular ribbon of cellulose in the bacterium Acetobacter xylinum takes place from linearly arranged, membrane-localized, cellulose-synthesizing and extrusion complexes that...Full Text Available
Growing evidences indicate that proteases are implicated in adipogenesis and in the onset of obesity. We previously reported that the cysteine protease cathepsin K (ctsk) is overexpressed in the white...Full Text Available
Previous work has implicated prefrontal cortices in selecting among and retrieving conceptual information stored elsewhere. However, recent neurophysiological work in monkeys suggests that prefrontal...Full Text Available
Although salamanders are characteristic amphibians in Holarctic temperate habitats, in tropical regions they have diversified evolutionarily only in tropical America. An adaptive radiation centered...Full Text Available
The concordance of standard big bang nucleosynthesis theory and the related observations of the light element isotopes (including some new higher {sup 4}He abundances) will be reviewed. Implications of BBN on chemical evolution, dark matter and constraints on particle properties will be discussed.
Autophagy is an evolutionarily conserved degradative pathway that has been implicated in a number of physiological events important for human health. This process was originally identified as a response...Full Text Available
Purposes1. To determine the optimal pelvic nodal clinical target volume for post-operative treatment of endometrial cancer. 2. To compare the DVH of different treatment planning...Full Text Available
Chagas disease, caused by infection with Trypanosoma cruzi, is an important cause of cardiovascular disease. It is increasingly clear that parasite-derived prostaglandins potently modulate...Full Text Available
BackgroundFormation of site specific genomic double strand breaks (DSBs), induced by the expression of a pair of engineered zinc-finger nucleases (ZFNs), dramatically increases the...Full Text Available
Allometric equations are often used to extrapolate traits in animals for which only body mass estimates are known, such as dinosaurs. One important decision can be whether these equations should be...Full Text Available
Calcium ions represent universal second messengers within neuronal cells integrating multiple cellular functions, such as release of neurotransmitters, gene expression, proliferation, excitability,...Full Text Available
This paper introduces briefly neutrinoless Double Beta Decay and discusses its implications for neutrino physics. After a presentation of general experimental concepts, such as the various proposed methodological approaches and the sensitivity, the current experimental situation is concisely reviewed.
AMP-activated protein kinase (AMPK) was initially viewed as energy sensor and activated by increased intracellular concentrations of AMP following nutrient deprivation. Physiological or pathological...Full Text Available
Amyloid precursor protein (APP), implicated in Alzheimer's disease, is a transmembrane protein of undetermined function. APP is cleaved by gamma-secretase that releases the APP intracellular domain...Full Text Available
Advanced Glycated End Products (AGEs) are formed by non-enzymatic protein glycation and are implicated in several physiological aspects including cell aging and diseases. Recent data indicate that bacteria...Full Text Available
BackgroundCentrosome aberrations can cause genomic instability and correlate with malignant progression in common human malignancies such as breast and prostate cancer. Deregulation...Full Text Available
Aberrant transglutaminase (TG) activity has been implicated in the pathology of numerous diseases including Huntington disease and Alzheimer disease. To fully characterize the role of TGs in...Full Text Available
A new method of random data analysis has been developed with special implications for membrane noise. The integral spectrometer uses overlapping broad-band filters of simple design, whose bandwidth...Full Text Available
The decline in immune function with aging, known as immunosenescence, has been implicated in evolutionarily diverse species, but the underlying molecular mechanisms are not understood. During aging...Full Text Available
The objective of this paper is to analyze the implications of varying degrees of financial openness for the impact of technology shocks on a real, small open economy with financial and informational frictions. Aggregate fluctuations and propagation mechanisms under increasing financial openness are investigated in a dynamic, stochastic, general equilibrium framework in the case of positive technology shocks. The imperfections in the economy in the form of informational asymmetries among the agents and uncertainty in the production process necessitate financial intermediation and collateralized borrowing in the economy. The reason to abstract from money in the setup of the framework is to be able to concentrate on the real implications of increasing financial openness for the effect of tech...
The Beyond the Standard Model Working Group discussed a variety of topics relating to exotic searches at current and future colliders, and the phenomenology of current models beyond the Standard Model. For example, various supersymmetric (SUSY) and extra dimensions search possibilities and constraints are presented. Fine-tuning implications of SUSY searches are derived. The implications of Higgs (non)-discovery are discussed, as well as the program HDECAY. The individual contributions are included seperately. Much of the enclosed work is original, although some is reviewed.
While there is growing interest in Real Time Pricing as a competitive tool, its adoption to date has been constrained by wariness on the part of many utilities and many of their customers. That wariness is not misplaced, for Real Time Pricing is not for everyone. In order for both utilities and their customers to benefit, the pricing system must be properly tailored for, and offered to, the appropriate audience. This paper discusses needs for identifying targets, implications of targeting of Real Time Pricing to various types of customers, and implications for design and marketing of such pricing systems. Examples from utility experiences are provided, and recommendations are offered for development of improved targeting of Real Time Pricing.
Immunoassays are versatile analytical techniques that had a leading role in various clinical applications, during the last four decades. The studies carried out by Rosalyn Yalow, Solomon Berson and Roger Ekins in the 1960s gave a breakthrough in the development of this novel analytical method. Sensitivity up to femtomolar concentrations, high specificity and universal application to different classes of molecular species made immunoassay a very useful tool in analytical investigation. The expertise acquired by immunochemists in producing antibodies against any antigen and the ability of radiochemists in labeling the antigens with "1"2"5I without affecting the active site are the two main factors responsible for the above development. There are concerns about the safety and health of humans due to the high-level contamination of environment by pesticides, industrial compounds and metals, anabolic steroids in milk and meat products, and presence of mycotoxins in food and feed ...
We provide a detailed overview of an ongoing, multinational test program that is developing aerosol data for some spent fuel sabotage scenarios on spent fuel transport and storage casks. Experiments are being performed to quantify the aerosolized materials plus volatilized fission products generated from actual spent fuel and surrogate material test rods, due to impact by a high energy density device, HEDD. The program participants in the U.S. plus Germany, France, and the U.K., part of the international Working Group for Sabotage Concerns of Transport and Storage Casks, WGSTSC have strongly supported and coordinated this research program. Sandia National Laboratories, SNL, has the lead role for conducting this research program; test program support is provided by both the U.S. Department of Energy and Nuclear Regulatory Commission. WGSTSC partners need this research to better understand potential radiological impacts from sabotage of nuclear ...
This handbook provides guidance in the application of quality assurance to measurement activities. It is intended to help those persons making measurements in applying quality assurance to their work activities by showing how laboratory practices and quality assurance requirements are integrated to provide control within those activities. The use of the guidance found in this handbook should help provide consistency in the interpretation of quality assurance requirements across all types of measurement laboratories. This handbook also can assist quality assurance personnel in understanding the relationships between laboratory practices and quality assurance requirements. The handbook is composed of three chapters and several appendices. Basic guidance is provided by the three chapters. In Chapter 1, the role of quality assurance in obtaining quality data and the importance of such data are discussed. Chapter 2 presents the ...
The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also ...
The OSHA's chemical occupational exposure standard for laboratories is an outgrowth of the previously issued Hazard Communication Standard. The standard relieves laboratories from complying with general industry standards but does not require compliance with specific guidelines. The heart of the standard is the creation of a Chemical Hygiene Plan (CHP) in every laboratory. The CHP addresses major issues such as safety equipment and procedures, work practices and training, the designation of a chemical hygiene officer, and the provision of medical consultation and examination for affected employees. This new standard, in effect as of 31 January, 1991, presents yet another regulatory challenge to laboratory managers but also will ensure a safer work environment for laboratory workers.
The aim of this paper is to obtain the effective potential of the non-topological soliton model at finite temperature with the assumption that the chemical potential {mu} of the system is different from zero and to analyse how the effective potential is influenced by changes in the chemical potential and temperature. (author)
Because of limitation on neutron-incident data, it is difficult to obtain global optical model potential for neutrons. In contrast, there are some global optical model potentials for proton in detail. It is interesting to convert the proton-incident global optical potentials into neutron-incident ones. In this study we introduce (N-Z)/A dependent symmetry potential terms into the global proton-incident optical potentials, and then obtain neutron-incident ones. The neutron potentials reproduce total cross sections in an acceptable degree. However, a comparison with potentials proposed by other authors brings about a confused situation in the sign of the symmetry terms. (author).
The performance of binary geothermal power plants can be improved through the proper choice of a working fluid, and optimization of component designs and operating conditions. This paper reviews the investigations at the Idaho National Engineering Laboratory (INEL) which are examining binary cycle performance improvements: for moderate temperature (350 to 400 F) resources with emphasis on how the improvements may be integrated into design of binary cycles. These investigations are examining performance improvements resulting from the supercritical vaporization of mixed hydrocarbon working fluids and achieving countercurrent integral condensation with these fluids, as well as the modification of the turbine inlet state points to achieve supersaturated turbine vapor expansions. For resources where the brine outlet temperature is restricted, the use of turbine exhaust recuperators is examined. The baseline plant used to determine improvements in plant performance ...
A retrospective study of the relationship of season to the absorption of radiolead in laboratory rats was performed using data representing 305 animals from 36 experiments over 6 calendar years. Male...Full Text Available
In a combined clinical, radiological, and laboratory study of 77 patients throughout the leprosy spectrum, 10 patients had an enthesitis which has not been described previously as far as is known and...Full Text Available