laboratory animal medicine: Topics by WorldWideScience.org

Use of a point-of-care beta-hydroxybutyrate sensor for detection of ketonemia in dogs.

This book discusses the procedures applied for the clinical nuclear medicine laboratory. The procedures are presented as proven guidelines. The chapters are included on quality assurance, radionuclide handling, and radiation safety.

1983-01-01

3

Ischemic-Anoxia of the Central Nervous System: Iron ...

The urine test strip is the most common test used to detect ketones in veterinary patients, but it can underestimate the degree of ketonuria and hence, ketonemia. Additionally, adequate urine samples for analysis may be difficult to obtain from dehydrated animals. The standard method used to detect and monitor ketonemia in human medicine is measurement of serum or whole blood beta-hydroxybutyrate (?HOB). A point-of-care (POC) analyzer has been validated for this purpose in humans. This study compared the accuracy of the POC device to an enzymatic reaction laboratory method for measurement of ?HOB in dogs. Although the POC sensor tended to overestimate ?HOB concentrations, there was good correlation (R(2) = 0.96) and good agreement between the 2 methods with a bias +/- precision of 0.0860 +/- 0.3410 mmol/L ?HOB. The POC ?HOB sensor can be useful for assessing ketonemia in dogs. PMID:21119867

2010-09-01

4

Seasonal changes in lead absorption in laboratory rats.

... Joint Staff and other US Military (ie, Army, Navy, Air ... The major products of this work are significant advances in ... Keywords: Dogs; Laboratory animals ...

1986-10-15

5

Medical explorations by radioisotopes in Lebanon

A retrospective study of the relationship of season to the absorption of radiolead in laboratory rats was performed using data representing 305 animals from 36 experiments over 6 calendar years. Male...Full Text Available

1987-08-01

6

Application of proportional counters in Polish medicine and agriculture

This study mainly concerns medical explorations by radioisotopes. Detectors with medical exams and applications are described. Ionisation chambers, semiconductor detectors and scintillation counters are also presented. Uses of radioisotopes in medicine in vivo and in vitro techniques are explained. Examples of scintiscanning are given like: angiography, nuclear cardiography and thyroid scintiscanning. The importance of the study is to present a panorama of nuclear medicine laboratories -at the time- in hospitals in Lebanon.

7

Utility of Recycled Bedding for Laboratory Rodents

In the laboratory of Elementary Particle Physics and Detectors at the Faculty of Physics and Nuclear Techniques of the University of Mining and Metallurgy, research works on the development of proportional counters for the detection of X- and soft {gamma}-rays and {alpha}, {beta} particles have been carried out As a result of optimization of counters characteristic parameters such as: energy resolution, life time, count rate effect and temperature effect the operating stability has been reached and the elaborated detectors have been applied not only in research laboratories, but also in Polish industry, medicine and agriculture. Examples of above mentioned applications have been presented in the paper. (author). 7 refs, 7 figs, 1 tab.

1996-12-31

8

The Relationship of Urinary Metabolites of Carbaryl/Naphthalene and Chlorpyrifos with Human Semen Quality

Animal facilities generate a large amount of used bedding containing excrement as medical waste. We developed a recycling system for used bedding that involves soft hydrothermal processing. In this...Full Text Available

2009-07-01

9

TLD assessment of mouse dosimetry during microCT imaging

Most of the general population is exposed to carbaryl and other contemporary-use insecticides at low levels. Studies of laboratory animals, in addition to limited human data, show an association between...Full Text Available

2004-12-01

10

Anti-ulcerogenic and in vitro antioxidant activities of Lagenaria breviflora (LB) whole fruit ethanolic extract in laboratory animals

Advances in laboratory animal imaging have provided new resources for noninvasive biomedical research. Among these technologies is microcomputed tomography (microCT) which is widely used to obtain high...Full Text Available

2008-09-01

11

Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network

Background:The present study was undertaken to evaluate the anti-ulcer and antioxidant activities of the ethanol extract of Lagenaria breviflora (EELB)...Full Text Available

2011-01-01

12

PIXE-PIGE analysis of some Indian medicinal plants

A remarkable discovery of recent years is that, despite the complexity of ageing, simple genetic interventions can increase lifespan and improve health during ageing in laboratory animals. The pathways...Full Text Available

2011-05-01

13

Solar-powered refrigerator unit with solar module and transport equipment as stand-alone compact system. Solarkuehlgeraet mit Solarmodul und Transportvorrichtung als autonomes Kompaktsystem

The quantitative estimation of various trace element concentrations in medicinal plants is necessary for determining their effectiveness in treating various diseases and for understanding their pharmacological action. Elemental concentrations of some selected medicinal plants of north east India was measured by proton induced X-ray emission (PIXE) and proton induced {gamma}-ray emission (PIGE) techniques. PIXE measurements were carried out using 2.4 MeV collimated protons from the 3 MV tandetron accelerator of NCCCM, Hyderabad (India) while the PIGE measurements were carried out using 3 MeV protons from the same accelerator in the same laboratory. Accuracy and precision of the techniques were assured by analyzing certified reference materials in the same experimental conditions. Various elements of biological importance in man's metabolism were found to be present in varying concentrations in the studied ...

2010-06-15

14

Determination of the content of elements in some wild medicinal plants of Uzbekistan by radioactivation analysis

A compact and energy independent solar-powered refrigeration unit was to be developed to store and transport small quantities of high-quality commodities needing refrigeration. This unit comprises the following matched components: thermo-electrical refrigerator unit, solar generator and transport equipment. The solar generator is a specially developed panel with 36 cells. This unit may best be used in human medicine, veterinary medicine, environmental protection analysis, laboratories and leisure time activities. (BWI)

1994-01-01

15

Effect of Tong Luo Jiu Nao on Ab-degrading enzymes in AD rat brains

The authors have developed a complex of activation methods of analysis using a nuclear reactor (nuclear activation analysis) and a cyclotron (charged-particle activation analysis). The methods have been used to determine the concentrations of more than 20 elements in five medicinal plants native to Uzbekistan: Syrian rue (Peganum harmala L.), plantain (Plantago lanceolata), peppermint (Mentha piperata L.), sage (Salvia officinalis L.), and ziziphora (Ziziphora bungeana Yur.). The results of radio-activation analysis were compared with the results of standard spectral analysis performed in another laboratory and the accuracy of the procedures developed was evaluated on the basis of the results.

1987-06-01

16

British Library Electronic Table of Contents (United Kingdom)

Ethnopharmacological relevance: Tong Luo Jiu Nao (TLJN) is a modern Chinese formula based on Traditional Chinese Medicine theory that has been used to treat ischemic cerebral stroke and vascular dementia. TLJN belongs to the ethnopharmacological family of medicines. In this study, we investigated the mechanism of the TLJN effect on Alzheimer's disease (AD). Aim of the study: To investigate the effect of TLJN on b-amyloid-degrading enzymes and learning and memory in the AD rat brain. Materials and methods: AD rats whose disease was induced by Ab25-35 injection into the bilateral hippocampus CA1 region were subjected to intragastric administration of various preparations. The experimental animals were healthy male Sprague-Dawley rats which were randomly divided into normal, sham, model, TLJN...

2011-01-01

17

[The contribution of the Military Medical Academy to space exploration].

Liposome technology. Volume II: Incorporation of drugs, proteins and genetic material

The article examines the contribution of the Military Medical Academy as an educational, research and medical institutions in the establishment and development of the national Russian manned spaceflight. Lists the names of the Academy's scientists, working in laboratories and in the Cosmonaut Training Center. In 1958 the academy was formed Department of Aviation Medicine from the research laboratories of aviation medicine, psychophysiology, and encephalography, a division of pressure chambers and furnaces. Direct contribution to the preparation of the first manned space flight made by graduates of the academy, E.A. Karpov (the first chief of Cosmonauts Training Center. Yuri Gagarin) and I.A. Kolosov. Over the half century history of the Russian Space Military Medical Academy, prepared and sent to the CPC Gagarin more than 110 of its graduates. PMID:21770320

2011-04-01

18

Compact free-electron laser at the Los Alamos National Laboratory

These three volumes cover liposome technology in pharmacology and medicine. Contributors emphasize methodology used in their own laboratories, and include a brief introduction, coverage of relevant literature, applications and critical evaluations for the methods they describe. Volume II presents procedures for the entrapment of a number of drugs, including genetic material, into selected types of liposomes.

1984-01-01

19

On the Industries of Animals.

The design and construction of second-generation free-electron laser (FEL) system at Los Alamos will be described. comprising state-of-the art components, this FEL system will be sufficiently compact, robust and user-friendly for application in industry, medicine, and research. 11 refs., 11 figs., 2 tabs.

1991-01-01

20

Transactions and Proceedings of the Royal Society of New Zealand 1868-1961

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1897-01-01

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21

Neuroprotective phenolics in medicinal plants.

Metabolism of benzo(a)pyrene by isolated perfused testis and testicular homogenate

Full Text Available

2010-10-01

22

Effective dose equivalent in nuclear medicine investigations

In an effort to improve the extrapolation of laboratory data to man and estimate risk of human reproductive toxicity associated with environmental exposure, the pharmacokinetic parameters of the testicular compartment are being studied. Of particular interest is the variety of enzyme systems capable of activating and detoxicating environmental chemicals and drugs. This report compares the metabolism of benzo(a)pyrene by the isolated perfused testis and testicular homogenates in vitro. The cell free in vitro system metabolized benzo(a)pyrene at a much greater rate than the perfused testis and produced a different spectrum of metabolites. Reliable laboratory prediction of biotransformation by the whole organ or intact animal is an essential aspect of reproductive toxicology.

1980-12-01

23

Centrifugal Extractors for Medicine Production

... radiation hazards hazards health hazards MEDICINE. SOMATICALLY

1984-05-07

24

The discovery and development of proteomic safety biomarkers for the detection of drug-induced liver toxicity

Continuous Countercurrent Process in Cascade of Centrifugal Extractors for Medicine Production

25

British Library Electronic Table of Contents (United Kingdom)

Biomarkers are biometric measurements that provide critical quantitative information about the biological condition of the animal or individual being tested. In drug safety studies, established toxicity biomarkers are used along with other conventional study data to determine dose-limiting organ toxicity, and to define species sensitivity for new chemical entities intended for possible use as human medicines. A continuing goal of drug safety scientists in the pharmaceutical industry is to discover and develop better trans-species biomarkers that can be used to determine target organ toxicities for preclinical species in short-term studies at dose levels that are some multiple of the intended human dose and again later in full development for monitoring clinical trials at lower therapeutic ...

2010-01-01

26

Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism

British Library Electronic Table of Contents (United Kingdom)

Translating experimental findings into clinically effective therapies is one of the major bottlenecks of modern medicine. As this has been particularly true for cerebrovascular research, attention has turned to the quality and validity of experimental cerebrovascular studies. We set out to assess the study design, statistical analyses, and reporting of cerebrovascular research. We assessed all original articles published in the Journal of Cerebral Blood Flow and Metabolism during the year 2008 against a checklist designed to capture the key attributes relating to study design, statistical analyses, and reporting. A total of 156 original publications were included (animal, in vitro, human). Few studies reported a primary research hypothesis, statement of purpose, or measures to safeguard in...

2011-01-01

27

Experimental study on Satureja montana as a treatment for premature ejaculation

British Library Electronic Table of Contents (United Kingdom)

Aim of the study: Satureja montana (winter savory) is a medicinal plant traditionally used to treat different disorders including male sexual dysfunction. In this study we evaluated the effect of Satureja montana hydroalcoholic extract on copulatory behavior of sexually potent male rats. Materials and methods: The extract was orally administered acutely or repetitively for 8 consecutive days at the doses of 25 and 50mg/kg. The main parameters of sexual behavior, mount (ML), intromission (IL), ejaculation (EL) latencies and post-ejaculatory interval (PEI), were evaluated in animals submitted to mating test and multiple ejaculations test. Testosterone serum levels were measured in rats acutely treated with Satureja montana extract dosed at 50mg/kg. In addition the open field test was conduct...

2011-01-01

28

Severity of Locomotor and Cardiovascular Derangements after Experimental High-Thoracic Spinal Cord Injury is Anesthesia Dependent in Rats.

Risk estimates of liver cancer due to aflatoxin exposure from peanuts and peanut products

Abstract Anesthetics affect outcomes from central nervous system (CNS) injuries differently. This is the first study to show how two commonly used anesthetics affect continuously recorded hemodynamic parameters and locomotor recovery during a 2-week period after two levels of contusion spinal cord injury (SCI) in rats. We hypothesized that the level of cardiovascular depression and recovery of locomotor function would be dependent upon the anesthetic used during SCI. Thirty-two adult female rats were subjected to a sham, 25-mm or 50-mm SCI at T3-4 under pentobarbital or isoflurane anesthesia. Mean arterial pressure (MAP) and heart rate (HR) were telemetrically recorded before, during, and after SCI. Locomotor function recovered best in the 25-mm-injured isoflurane-anesthetized animals. There was no significant difference in locomotor recovery between the 25-mm-injured pentobarbital-anesthetized animals and the 50-mm-injured ...

2011-08-01

29

Health, Safety, and Environment Division: Annual progress report 1987

An assessment was undertaken of the risk of liver cancer in the USA associated with aflatoxin ingestion from peanuts. Both laboratory-animal data and epidemiological data collected from the scientific literature and several prominent mathematical extrapolation techniques were used. Risk estimates differed by a factor of greater than 1000 when the extrapolated results of three selected animal studies were analysed. Dose-response data for the male Fischer rat, the most sensitive mammalian species studied, produced an estimate of 158 cases of liver cancer per year in the USA at current levels of aflatoxin exposure. An estimate of 58 annual cases was predicted on the basis of epidemiological data of populations in Africa and Thailand.

1984-06-01

30

New facility design and work method for the quantitative fit testing laboratory. Master's thesis

The primary responsibility of the Health, Safety, and Environment (HSE) Division at the Los Alamos National Laboratory is to provide comprehensive occupational health and safety programs, waste processing, and environment protection. These activities are designed to protect the worker, the public, and the environment. Many disciplines are required to meet the responsibilities, including radiation protection, industrial hygiene, safety, occupational medicine, environmental science, epidemiology, and waste management. New and challenging health and safety problems arise occasionally from the diverse research and development work of the Laboratory. Research programs in HSE Division often stem from these applied needs. These programs continue but are also extended, as needed to study specific problems for the Department of Energy and to help develop better occupational health and safety practices.

1988-04-01

31

On Immortality in the Animal World.

The United States Air Force School of Aerospace Medicine (USAFSAM) tests the quantitative fit of masks which are worn by military personnel during nuclear, biological, and chemical warfare. Subjects are placed in a Dynatech-Frontier Fit Testing Chamber, salt air is fed into the chamber, and samples of air are drawn from the mask and the chamber. The ratio of salt air outside the mask to salt air inside the mask is called the quantitative fit factor. A motion-time study was conducted to evaluate the efficiency of the layout and work method presently used in the laboratory. A link analysis was done to determine equipment priorities, and the link data and design guidelines were used to develop three proposed laboratory designs. The proposals were evaluated by projecting the time and motion efficiency, and the energy expended working in each design. Also evaluated were the lengths of the equipment links for each proposal, and ...

1989-05-01

32

Transactions and Proceedings of the Royal Society of New Zealand 1868-1961

Full Text Available

1890-01-01

33

Use frequency of traditional Chinese medicine in Taiwan

Experimental medicine 1000 years ago

BackgroundUse of Traditional Chinese medicine (TCM), an important category of complementary and alternative medicine (CAM), has increased substantially in Western countries during...Full Text Available

34

Drying of medicinal plants with solar energy. Trocknung von Arzneipflanzen mit Solarenergie

Little is known about the state of experimentation in the field of medicine during the Medieval Islamic era. With few exceptions, most of the contemporary sources on history of medicine propagate the...Full Text Available

2011-05-01

35

Diagnostic and therapeutic evaluation of "1"1"1In-vinorelbine-liposomes in a human colorectal carcinoma HT-29/luc-bearing animal model

Due to the high investment and operation costs incurred by dryers up to 50% of the proceeds from the cultivation of medicinal plants have to be spent on drying. This study was conducted in order to determine whether these costs can be lowered when solar energy is used. As little is known about the drying behaviour of medicinal plants even today one selected sage and camomile in order to study the influence of temperature, relative humidity, and drying air velocity on drying time and drug quality. Laboratory results were used as a basis for developing a solar hothouse dryer for medicinal plants which uses the whole roof surface as solar collectors with a batch dryer set up within the hothouse. In contrast to dryers of this type used up to now a foil green house with a gable roof was used. Installation of a central heating system helps to avoid bottlenecks, allows drying at night and increases plant flow ...

1991-12-01

36

A study of relative regional cerebral blood flow using N-isopropyl-p-["1"2"5I]-iodoamphetamine ("1"2"5I-IMP) in carbon monoxide exposed rats

Colorectal carcinoma is a highly prevalent and common cause of cancer in Taiwan. There is still no available cure for this malignant disease. To address this issue, we applied the multimodality of molecular imaging to explore the efficacy of diagnostic and therapeutic nanoradiopharmaceuticals in an animal model of human colorectal adenocarcinoma [colorectal cancer (CRC)] that stably expresses luciferase (luc) as a reporter. In this study, an in vivo therapeutic efficacy evaluation of dual-nanoliposome (100 nm in diameter) encaged vinorelbine (VNB) and "1"1"1In-oxine on HT-29/luc mouse xenografts was carried out. HT-29/luc tumor cells were transplanted subcutaneously into male SCID mice. Multimodality of molecular imaging approaches including bioluminescence imaging (BLI), gamma scintigraphy, whole-body autoradiography (WBAR) and in vivo tumor growth tracing, histopathology and biochemistry/hematology analyses were applied on xenografted SCID mice to study the ...

2008-07-01

37

A study of relative regional cerebral blood flow using N-isopropyl-p-( sup 125 I)-iodoamphetamine ( sup 125 I-IMP) in carbon monoxide exposed rats

The influence of carbon monoxide (CO) exposure on regional cerebral blood flow (r-CBF) in rat brain was studied using autoradiography and "1"2"5I-IMP. Fuji computed radiography (FCR) was used to obtain improved autoradiograms in this study. R-CBF was determined in a relative measure by calculating hippocampus/cortex and putamen/cortex ratios of RI accumulation from the autoradiogram using a densitometer. Comparison of autoradiograms with pathological findings in the area of the hippocampus and putamen yield the following results. In the animals that were exposed to 6400 ppm or 10000 ppm of CO for 30 minutes, and then were followed up for 2 weeks without further exposure, r-CBF was decreased but no pathological changes occurred. In the animals that were exposed to 6400 ppm or 10000 ppm of CO, and then were followed up for 4 weeks without further exposure, pathological changes appeared. In animals exposed to 3200 ppm of CO, ...

38

Synthetic and bioengineered products in nuclear medicine and drug delivery

The influence of carbon monoxide (CO) exposure on regional cerebral blood flow (r-CBF) in rat brain was studied using autoradiography and {sup 125}I-IMP. Fuji computed radiography (FCR) was used to obtain improved autoradiograms in this study. R-CBF was determined in a relative measure by calculating hippocampus/cortex and putamen/cortex ratios of RI accumulation from the autoradiogram using a densitometer. Comparison of autoradiograms with pathological findings in the area of the hippocampus and putamen yield the following results. In the animals that were exposed to 6400 ppm or 10000 ppm of CO for 30 minutes, and then were followed up for 2 weeks without further exposure, r-CBF was decreased but no pathological changes occurred. In the animals that were exposed to 6400 ppm or 10000 ppm of CO, and then were followed up for 4 weeks without further exposure, pathological changes appeared. In animals exposed to 3200 ppm of ...

1990-11-01

39

Search for Medicinal Plants on Improvable Effect of Intestinal Microflora

No abstract prepared.

1999-07-01

40

Pectins from medicinal plants and their anti-ulcer activity

Full Text Available

2007-02-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

41

Molecular Imaging in the Age of Genomic Medicine

No abstract prepared.

2008-07-01

42

Insect Pests Occurring in Storage Medicinal Plants

Full Text Available

2007-06-01

43

Functional Properties of Medicinal Plant Extracts

Full Text Available

2007-12-01

44

Evidence-based Research in Complementary and Alternative Medicine I: History

Full Text Available

2006-10-01

45

Arabinogalactans isolated from the medicinal plant Maytenus ilicifolia

Contemporary Western medicine has witnessed a fragmentation of our conceptualization of the medical endeavor into ‘traditional medicine’ and ‘non-traditional medicine’....Full Text Available

2005-12-01

46

Antioxidant activity of medicinal plant extracts cultivated in Jecheon

No abstract prepared.

2006-07-01

47

Antioxidant Activities of Vietnamese Medicinal Plants

Full Text Available

2007-06-01

48

Antinociceptive activity of some Bangladeshi medicinal plant extracts

Full Text Available

2006-03-01

49

Antimicrobial activity of Mongolian medicinal plants

Full Text Available

2006-06-01

50

Antimicrobial activity of Mongolian medicinal plants

Full Text Available

51

Antimicribial and Antioxidant Activities of Ethanol Extracts of Medicinal Plants

Full Text Available

2008-03-01

52

Acidic heteroxylans from medicinal plants and their antiulcer activity

Full Text Available

2005-03-01

53

State of work for services provided by the Waste Sampling and Characterization Facility for effluent monitoring

No abstract prepared.

2008-07-01

54

Vasorelaxant Activities of Aqueous Extracts from Twenty Medicinal Plants Used in Oriental Medicines in Isolated Rat Aorta

This document defines the services the Waste Sampling and Characterization Facility (WSCF) shall provide Effluent Monitoring (EM) throughout the calendar year for analysis. The internal memo contained in Appendix A identifies the samples Em plans to submit for analysis in CY-1995. Analysis of effluent (liquid and air discharges) and environmental (air, liquid, animal, and vegetative) samples is required using standard laboratory procedures, in accordance with regulatory and control requirements. This report describes regulatory reporting requirements and WSCF services and data quality objectives.

55

Alexandria Journal of Medicine - Elsevier

Full Text Available

2010-09-01

56

Radioactive decay data tables

... Alexandria Journal of Medicine-The Alexandria Journal of Medicine publishes concise, original articles and contributions in the broad field of medical scie ..... Alexandria Journal of Medicine - Elsevier Home Products User Resources About Us Support & Contact Elsevier Websites Advanced Product Search ...Browse Journals Alexandria Journal of Medicine Alexandria Journal of Medicine Produced and hosted on behalf of the Alexandria University Faculty of Medicine Additional Information ...for Editors Reviewers Log in as Reviewer Advertisers/Sponsors Societies ISSN: 2090-5068 Imprint: Alexandria University Faculty of Medicine Actions Submit Article ...

57

Laboratory techniques for determining the effects of pyridostigmine bromide. Interim report, May 1985-May 1986

The estimation of radiation dose to man from either external or internal exposure to radionuclides requires a knowledge of the energies and intensities of the atomic and nuclear radiations emitted during the radioactive decay process. The availability of evaluated decay data for the large number of radionuclides of interest is thus of fundamental importance for radiation dosimetry. This handbook contains a compilation of decay data for approximately 500 radionuclides. These data constitute an evaluated data file constructed for use in the radiological assessment activities of the Technology Assessments Section of the Health and Safety Research Division at Oak Ridge National Laboratory. The radionuclides selected for this handbook include those occurring naturally in the environment, those of potential importance in routine or accidental releases from the nuclear fuel cycle, those of current interest in nuclear medicine and fusion reactor ...

1981-01-01

58

In vivo and in vitro evaluation of dota-lanreotide radiolabelled with gallium-67

The USAF Surgeon General approved pyridostigmine bromide (PB) pretreatment for flying personnel as of 21 March 1986. However, specific side effects resulting from taking PB during high sustained + G/sub z/ stress, altitude stress, and periods of potential spatial disorientation had not yet been fully investigated. The USAF school of Aerospace Medicine (UASFSAM), Crew Technology Division, was therefore tasked with this clinical research effort. For effective investigation of these potential problem areas, rapid and accurate methods have had to be established for determining the blood plasma PB levels and the resultant inhibition of acetylcholinesterase activity. The basic purpose of this report is to describe in detail the analytical techniques used at USAFSAM to support the clinical research programs involving the physiological and performance aspects of USAF aircrews taking PB.

1986-11-01

59

Production capabilities in US nuclear reactors for medical radioisotopes

One of the refinements of modern Nuclear Medicine is the capacity of providing dynamic and kinetics images of the administered radiopharmaceutical, reproducing its transport mechanism, action sites, receptor binding and excretion route. With the continues technological advances new radiopharmaceuticals have been developed in order to express higher specificity and with higher characters of affinity between receptor/complex. One radiopharmaceutical is formed by a reagent or bio molecule that has in its structure a radioisotope, that has the objectives of carrying it to the organs of affinity or to benign or malign tumoral process. Somatostatin inhibits the growing and proliferation of several tumoral cells. Somatostatin analogs bind to somatostatic receptors that are expressed in different kind of neoplasia DOTA-LANREOTIDE (DOTALAN) is an octapeptide analog to somatostatin. The interest of labeling the bio conjugate with gallium-67 in Nuclear ...

60

PET/MRI hybrid imaging: devices and initial results

The availability of reactor-produced radioisotopes in the United States for use in medical research and nuclear medicine has traditionally depended on facilities which are an integral part of the US national laboratories and a few reactors at universities. One exception is the reactor in Sterling Forest, New York, originally operated as part of the Cintichem (Union Carbide) system, which is currently in the process of permanent shutdown. Since there are no industry-run reactors in the US, the national laboratories and universities thus play a critical role in providing reactor-produced radioisotopes for medical research and clinical use. The goal of this survey is to provide a comprehensive summary of these production capabilities. With the temporary shutdown of the Oak Ridge National Laboratory (ORNL) High Flux Isotope Reactor (HFIR) in November 1986, the radioisotopes required for DOE-supported ...

1992-11-01

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61

Calibration methods of plane-parallel ionization chambers used in electron dosimetry; Metodos de calibracao de camaras de ionizacao de placas paralelas para dosimetria de feixes de eletrons

The combination of functional and morphological imaging technologies such as positron emission tomography (PET) and X-ray computed tomography (CT) has shown its value in the clinical and preclinical field. However, CT provides only very limited soft-tissue contrast and exposes the examined patient or laboratory animal to a high X-ray radiation dose. In comparison to CT, magnetic resonance tomography (MRI) provides excellent soft-tissue contrast and allows for nuclear magnetic resonance spectroscopy (NMRS) or functional MRI (fMRI). Thus, the combination of PET and MRI has been pursued for several years. First approaches have succeeded using conventional photo multiplier tube (PMT) technology together with light fibers to transfer scintillation light away from the high magnetic field. Latest PET/MRI developments use solid-state light detectors that can be operated even at high magnetic fields. Initial pilot studies with prototype ...

2008-06-01

62

Elk and Deer Study, Material Disposal Area G, Technical Area 54: Source document

The use of linear accelerators in radiotherapy is of great importance in Medicine, and according to international recommendations the electron beam dosimetry has to be performed using plane-parallel ionization chambers, previously calibrated in standard gamma radiation fields at accredited laboratories. In this work, calibration methods of plane-parallel ionization chambers used in dosimetry procedures of high energy electron beams of clinical accelerators were presented, tested and intercompared. The experiments were carried out using gamma radiation beams of {sup 60} Co at the Calibration Laboratory of Clinical Dosemeters at IPEN and electron beams od 4 to 16 MeV at the Radiotherapy Department of Hospital Israelita Albert Einstein, Sao Paulo. A method was chosen to be established at IPEN. Proposals of the calibration procedure, calibration certificate and data sheets are presented. (author)

1999-07-01

63

Capacity issues in transport of animals for slaughtering in Gilde

As nuclear research has become more prevalent, environmental contamination from the disposal of radioactive waste has become a prominent issue. At Los Alamos National Laboratory (LANL) in northern New Mexico, radioactive contamination from disposal operations has raised some very specific concerns. Material Disposal Area G (Area G) is the primary low-level radioactive waste disposal site at LANL and occupies an area adjacent to land belonging to the Native American community of the Pueblo of San Ildefonso. Analyses of soil and vegetation collected from the perimeter of Area G have shown concentrations of radionuclides greater than background concentrations established for northern New Mexico. As a result, Pueblo residents had become concerned that contaminants from Area G could enter tribal lands through various ecological pathways. The residents specifically questioned the safety of consuming meat from elk and deer that forage near Area G and then migrate onto ...

1999-09-01

64

Norwegian Open Research Archives (NORA)

Full Text Available

65

Consensus Recommendations of Pediatric Transfusion Medicine Objectives for Clinical Pathology Residency Training Programs

Heavy Metals Effect on Animal Cells

BACKGROUNDPediatric transfusion medicine (PTM) is a subspecialty of transfusion medicine (TM) with no formal training program and few specialists. The Pediatric Transfusion...Full Text Available

2010-05-01

66

Serological testing-An alternative to boosters?

Studies of the Superheavy-metal Effect as a Stress-factor on Protein Biosynthesis and Cytoskeleton Integrity in Animal Cells

67

British Library Electronic Table of Contents (United Kingdom)

The issue of the duration of immunity, particularly for the modified live viral components of veterinary vaccines, has been a significant part of the recent vaccination debate. One manufacturer has increased the recommended booster interval for these components to 3 years give name and another now states `up to 4 years' immunity.There remain many unanswered questions regarding this duration of immunity (DOI). Studies suitable for data sheet claims are time consuming and costly and can only be performed in laboratory dogs under tightly controlled conditions. Evidence from rabies serology testing in the UK shows that the response of individual animals to routine vaccination is highly variable. Much of the published field evidence on the persistence of antibody titres originates from North Am...

2006-01-01

68

Penile Rehabilitation after Radical Prostatectomy: Where Do We Stand and Where Are We Going?

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT Introduction. Postprostatectomy erectile dysfunction (ED) remains a serious quality-of-life issue. Recent advances in the understanding of the mechanism of postprostatectomy ED have stimulated great attention toward penile rehabilitation. Aim. This review presents and analyzes a contemporary series of the recent medical literature pertaining to penile rehabilitation therapy after radical prostatectomy (RP). Main Outcome Measures. The laboratory and clinical studies related to penile rehabilitation are analyzed. The validity of the methodology and the conclusion of the findings from each study are determined. Methods. The published and presented reports dealing with penile rehabilitation following RP in human and cavernous nerve injury in animal models are reviewed. Results. Exciti...

2007-01-01

69

PET/MRI hybrid imaging: devices and initial results

British Library Electronic Table of Contents (United Kingdom)

The combination of functional and morphological imaging technologies such as positron emission tomography (PET) and X-ray computed tomography (CT) has shown its value in the clinical and preclinical field. However, CT provides only very limited soft-tissue contrast and exposes the examined patient or laboratory animal to a high X-ray radiation dose. In comparison to CT, magnetic resonance tomography (MRI) provides excellent soft-tissue contrast and allows for nuclear magnetic resonance spectroscopy (NMRS) or functional MRI (fMRI). Thus, the combination of PET and MRI has been pursued for several years. First approaches have succeeded using conventional photo multiplier tube (PMT) technology together with light fibers to transfer scintillation light away from the high magnetic field. Latest...

2008-01-01

70

Continuing the search for a fundamental law of mortality

Continuing the search for a fundamental law of mortality

For 170 years, scientists have attempted to explain why consistent temporal patterns of death are observed among individuals within populations. Historical efforts to identify a {open_quotes}law of mortality{close_quotes} from these patterns ended in 1935 when it was declared that such a law did not exist. These empirical tests for a law of mortality were constructed using mortality curves based on all causes of death. We predicted that patterns of mortality consistent with the historical concept of a law would be revealed if mortality curves for species were constructed using only senescent causes of death. Using data on senescent mortality for laboratory animals and humans, we demonstrate that patterns of mortality overlap when compared on a biologically comparable time scale. These results are consistent with the existence of a law of mortality following sexual maturity as asserted by Benjamin Gompertz and Raymond Pearl. The societal, ...

1997-08-01

71

Increasing access to Latin American social medicine resources: a preliminary report*

for 170 years, scientists have attempted to explain why consistent temporal patterns of death are observed among individuals within populations. Historical efforts to identify a `law of mortality` from these patterns ended in 1935 when it was declared that such a law did not exist. These empirical tests for a law of mortality were constructed using mortality curves based on all causes of death. We predicted patterns of mortality consistent with the historical concept of a law would be revealed if mortality curves for species were constructed using only senescent causes of death. Using data on senescent mortality for laboratory animals and humans, we demonstrate patterns of mortality overlap when compared on a biologically comparable time scale. The results are consistent with the existence of a law of mortality following sexual maturity. The societal, medical, and research implications of such a law are discussed.

1996-03-01

72

DNA methods for identification of Chinese medicinal materials

Purpose: This preliminary report describes the development and implementation of a project to improve access to literature in Latin American social medicine (LASM).Methods:...Full Text Available

2003-10-01

73

Complementary and alternative medicine in the management of hypertension in an urban Nigerian community

As adulterated and substituted Chinese medicinal materials are common in the market, therapeutic effectiveness of such materials cannot be guaranteed. Identification at species-, strain- and locality-levels,...Full Text Available

74

A Monograph Assignment as an Integrative Application of Evidence-Based Medicine and Pharmacoeconomic Principles

BackgroundHypertension is a common non communicable condition worldwide. In developing countries (including Nigeria), the use of complementary and alternative medicine (CAM) is common....Full Text Available

75

The coordination chemistry of technetium and rhenium and applications to nuclear medicine. Final report

ObjectiveTo describe the development and assessment of monographs as an assignment to incorporate evidence-based medicine (EBM) and pharmacoeconomic principles into a third-year...Full Text Available

2011-02-10

76

The Effect of Garlic and Medicinal Plants Extracts on the Liver Function and Lipid Metabolism of Rats Administered with Alcohol

No abstract prepared.

1996-12-31

77

Speciation of metals in medicinal plants under different stress condition by HPLC-ICP-MS

Full Text Available

2009-05-01

78

Space Biology and Medicine

No abstract prepared.

2005-07-01

79

Some Medicinal Plants Suppressed Reproduction of Meloidogyne hapla on Codonopsis lanceolata Trautv

Volume IV is devoted to examining the medical and associated organizational measures used to

2004-01-01

80

Screening of some Bangladeshi medicinal plants for in vitro antibacterial activity

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2006-12-01

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81

Screening of Medicinal Plants to Suppress Population of Meloidogyne hapla in Codonopsis lanceolata Trautv

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2008-09-01

82

Screening of Medicinal Plants for Development of Functional Food Ingredients with Anti-Obesity

Full Text Available

2006-12-01

83

Screening of Antibacterial Agent Against Streptococcus mutans from Natural and Medicinal Plants,

Full Text Available

2006-09-01

84

Screening and Extraction Condition of Antiaging Bioactive Substances from Medicinal Plants

Full Text Available

2005-10-01

85

Screening and Extraction Condition of Anti-skin Aging Elastase Inhibitor from Medicinal Plants

Full Text Available

2005-10-01

86

Protective Effect of Some Medicinal Plants on tert-Butyl Hydroperoxide-Induced Oxidative Stress in Human Keratinocytes

Full Text Available

2005-12-01

87

Peroxyl Radical Scavenging Capacity of Extracts and Isolated Components from Selected Medicinal Plants

Full Text Available

2008-12-01

88

Multi-loci Molecular Characterisation of Endophytic Fungi Isolated from Five Medicinal Plants of Meghalaya, India

Full Text Available

2010-06-01

89

MEDICINAL COMPOSITION FOR TREATING AND/OR PREVENTING RHEUMATOID ARTHRITIS

Full Text Available

2011-06-01

90

J-STORE (Japan)

Full Text Available

2011-03-22

91

Localization of "2"0"3Pb-chloride in myocardial infarction

Lipid Compositions Changes of Seasoned Pork Prepared with Medicinal Plant Extracts During Storage

... AND NUCLEAR MEDICINE biological localization cardiovascular diseases

92

Lepidium sativum (Garden cress): a review of contemporary literature and medicinal properties

Full Text Available

2007-12-01

93

Kinds and Occurring Time of Insect Pests in Medicinal Plant Garden

Full Text Available

2007-12-01

94

In Vitro Antiviral Activity of Aqueous Extracts from Korean Medicinal Plants Against Influenza Virus Type A

Full Text Available

2007-12-01

95

Importance of anthropomorphic phantoms in nuclear medicine

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2005-10-01

96

Images in cardiovascular medicine. Coronary artery fistula with a huge aneurysm treated by transcatheter coil embolization.

... Brasileira de Biociencias Nucleares (SBBN), Recife, PE (Brazil) INIS-BR--9282

2010-10-27

97

High Throughput Screening on Angiogenesis Inhibitor and Promoter of Medicinal Plants using a Protein Microarray Chip

PMID:17159065

2006-12-12

98

Elemental content determination in leaves and extracts of Casearia medicinal plant by neutron activation analysis

Full Text Available

2007-04-01

99

Effects of extracts of medicinal plants in the parasitaemia of Trypanosoma cruzi and in the biodistribution of the technetium-{sup 99m}

No abstract prepared.

2005-07-01

100

Effects of Single or Mixed Supplements of Plant Extract, Fermented Medicinal Plants and Lactobacillus on Growth Performance in Broilers

No abstract prepared.

2008-10-15

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101

Effects of Medicinal Plants on the Quality and Physiological Functionalities of Traditional Ginseng Wine

Full Text Available

2007-09-01

102

Effect of the medicinal plant Echinacea purpurea on the bioavailability of the radiopharmaceutical {sup 99M}TC-sodium pertechnetate

Full Text Available

2007-06-01

103

Effect of Garlic and Medicinal Plants Composites on Antioxidant Activity and Lipid Levels of Liver in Hypercholesterolemic Rats

No abstract prepared.

2008-10-15

104

Drying of medicinal plants with solar energy utilization

Full Text Available

2009-12-01

105

Determination of metals in medicinal plants and soil from Amazon area by neutron activation analysis and ICP-MS

In the paper, a potential of solar energy for drying of medicinal plants in Polish conditions is estimated and development of solar drying technologies is presented. The results of economic assessment of flat-plate solar collectors applied for drying of medicinal plants on a farm are promising. In some specific conditions, e.g. drying of wild grown medicinal plants in remote areas, even application of photovoltaic modules for driving of a fan of a solar dryer is a profitable option and enables easy control of the drying air temperature.

1997-10-01

106

Chromosome Numbers and Karyotype Analyses for 33 Taxa of Medicinal Plants in Korea

No abstract prepared.

2005-07-01

107

Chemical and biological aspects of an arabinogalactan from the medicinal herb Phyllanthus niruri (quebra-pedra)

Full Text Available

2008-06-01

108

Bulgarian population exposure resulting from diagnostic nuclear-medicine applications

No abstract prepared.

2005-07-01

109

Brine Shrimp Toxicity of Fractionated Extracts of Malaysian Medicinal Plants

... populations radiation doses RADIOACTIVE MATERIALS. SOMATICALLY

1980-10-26

110

Antioxidative and Antimicrobial Activities of Medicinal Plant Extracts for Screening Phytobiotic Material

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2000-09-01

111

Antioxidative Activity of Hot Water Extracts from Medicinal Plants

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2007-10-01

112

Antioxidative Activity and Nitrite Scavenging Effect of the Composites Containing Medicinal Plant Extracts

Full Text Available

2006-01-01

113

Antioxidant and Alcohol Dehydrogenase Activity of Water Extracts From Abalone Containing Medicinal Plants

Full Text Available

2007-08-01

114

Antioxidant Characteristics and Preparation of Chocolate Added with Sochungryong-Tang (Oriental Medicinal Plants Extract)

Full Text Available

2008-04-01

115

Antimicrobial Effect of Medicinal Plants against Methicillin-Resistant Staphylococcus aureus (MRSA)

Full Text Available

2005-10-01

116

Antihyperglycemia Effect of Medicinal Plants Mixture in Streptozotocin-Induced Diabetic Rats

Full Text Available

2007-03-01

117

Aldose reductase inhibitory activity and anti catraract potential of some traditionally acclaimed antidiabetic medicinal plants

Full Text Available

2008-12-01

118

Narrative medicine and healthcare reform.

Full Text Available

2009-09-01

119

Analytical methods for heavy metals in herbal medicines

Narrative medicine is one of medicine's most important internal reforms, and it should be a critical dimension of healthcare debate. Healthcare reform must eventually ask not only how do we pay for healthcare and how do we distribute it, but more fundamentally, what kind of healthcare do we want? It must ask, in short, what are the goals of medicine? Yet, even though narrative medicine is crucial to answering these pivotal and inescapable questions, it is not easy to describe. Many of its core claims go against the grain of common sense thinking about medicine. This article argues that the best way to understand narrative medicine is to tell a story that puts its emergence in historical context. PMID:21053060

2011-03-01

120

British Library Electronic Table of Contents (United Kingdom)

Abstract Introduction - It is estimated that about 70-80% of the world's population relies on non-conventional medicine, mainly of herbal origin. However, owing to the nature and sources of herbal medicines, they are sometimes contaminated with toxic heavy metals such as lead, arsenic, mercury and cadmium, which impose serious health risks to consumers. It is critical to analyse source materials for heavy metals in order to ensure that their concentrations meet the related standards or regulations limiting their concentrations in herbal medicines. In this review, different analytical methods for analysis of heavy metals in herbal medicines are discussed. Objective - To provide a comprehensive review of the current state of the art in analytical methods used to detect heavy metals in herbal...

2011-01-01

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121

Expanding the role of the cost engineer

Vascular plants of the Hanford Site

There have been many questions about the costs of providing medical services. These questions have resulted in the development of Resource-Based Relative Values Scale (RBRVS) at the national level. Policymakers view RBRVS as a potential tool to pay physicians. The questions, about the cost of operations of HSE-2 at Los Alamos National Laboratory, revolve around doing routine occupation health physicals for the Laboratory. Generally, these questions are concerned about why the costs appear to be high relative to what private physician suggests the costs should be. There is also an interest in trying to find methods to reduce these costs if possible. Many of the tools developed to help in construction estimating can be applied to estimating medical costs. With the need to perform many thousands of physicals each year the saving of even a few dollars for each exam can quickly add up to a large saving. There are a number of different types of ...

1989-01-01

122

Tamper indicating packaging

An updated listing of the vascular plants of the Hanford Site is provided, along with discussions of how humans may interact with local plants and have influenced the regional flora. Based on examinations of herbarium collections at the Westinghouse Hanford Company, Pacific Northwest Laboratory, Washington State University, and Brigham Young University, 590 vascular plant species have been identified on or near the Hanford Site. This is more than twice the number of species on previously published lists of Hanford Site vascular plants. A review of the plant species that are currently listed as endangered, threatened, sensitive, or otherwise of concern to the Washington State Natural Heritage Program and the Federal Fish and Wildlife Service is included. Color photographs of selected species are included to aid identification. Lists are provided of the Hanford Site plant species that could be used as food and medicinal sources and of those ...

1992-07-01

123

Study of the Photon Strength Functions for Gadolinium Isotopes with the DANCE Array

Protecting sensitive items from undetected tampering in an unattended environment is crucial to the success of non-proliferation efforts relying on the verification of critical activities. Tamper Indicating Packaging (TIP) technologies are applied to containers, packages, and equipment that require an indication of a tamper attempt. Examples include: the transportation and storage of nuclear material, the operation and shipment of surveillance equipment and monitoring sensors, and the retail storage of medicine and food products. The spectrum of adversarial tampering ranges from attempted concealment of a pin-hole sized penetration to the complete container replacement, which would involve counterfeiting efforts of various degrees. Sandia National Laboratories (SNL) has developed a technology base for advanced TIP materials, sensors, designs, and processes which can be adapted to various future monitoring systems. The purpose of this technology ...

1994-07-17

124

State-in-the-art of applications of shock wave research and its future; Shogekiha no oyo gijutsu no genjo to shorai

The gadolinium isotopes are interesting for reactor applications as well as for medicine and astrophysics. The gadolinium isotopes have some of the largest neutron capture cross sections. As a consequence they are used in the control rod in reactor fuel assembly. From the basic science point of view, there are seven stable isotopes of gadolinium with varying degrees of deformation. Therefore they provide a good testing ground for the study of deformation dependent structure such as the scissors mode. Decay gamma rays following neutron capture on Gd isotopes are detected by the DANCE array, which is located at flight path 14 at the Lujan Neutron Scattering Center at Los Alamos National Laboratory. The high segmentation and close packing of the detector array enable gamma-ray multiplicity measurements. The calorimetric properties of the DANCE array coupled with the neutron time-of-flight technique enables one to gate on a specific resonance of a ...

2009-03-10

125

Separation Science and Technology. Semiannual progress report, April 1993--September 1993

A shock wave appears when the release of accumulated energy is instantaneous. For instance, it accompanies gunpowder explosion, electric discharge, laser beam convergence, collision of high-speed objects, release of high-pressure gas, and supersonic flight. The shock wave research center of Institute of Fluid Science, Tohoku University, is engaged in researches to elucidate the basics of various shock wave phenomena and to apply the fruit to engineering, science, and medicine. In this report, some examples of recent application studies at the center are described, and the trend of shock wave researches in the future is introduced. The ultimate state of the stagnation point of a nozzle flow simulating a reentry into the atmosphere is produced by shock wave compression in a free piston shock tube which is a ground-borne experimental apparatus. Los Alamos National Laboratory, U.S., succeeded in generating metallic hydrogen of a crystalline ...

1999-03-15

126

Development of new radiopharmaceuticals

This document reports on the work done by the Separations Science and Technology Programs of the Chemical Technology Division, Argonne National Laboratory, in the period April-September 1993. This effort is mainly concerned with developing the TRUEX process for removing and concentrating actinides from acidic waste streams contaminated with transuranic (TRU) elements. The objectives of TRUEX processing are to recover valuable TRU elements and to lower disposal costs for the nonTRU waste product of the process. Other projects are underway with the objective of developing (1) evaporation technology for concentrating radioactive waste and product streams such as those generated by the TRUEX process, (2) treatment schemes for liquid wastes stored or being generated at Argonne, (3) a process based on sorbing modified TRUEX solvent on magnetic beads to be used for separation of contaminants from radioactive and hazardous waste streams, and (4) a process that uses ...

1996-01-01

127

Concise review: expanding roles for hematopoietic cellular therapy and the blood transfusion services.

The possibilities to design and prepare better and more organ-specific radiopharmaceuticals for diagnostic nuclear medicine has increased dramatically in the recent past with a deeper understanding of the relationships between chemical structure and biological activity. Whereas most of the research is performed in well-funded laboratories of industrialized countries, there are several developing countries with adequate resources and expertise as to undertake fruitful research in the field of radiopharmacy. With the aim of promoting advanced research in radiopharmacy by developing new radiodiagnostics agents, in particular, hepatobiliary imaging agents labelled with "9"9"mTc, and to facilitate exchange of information, the IAEA has established in 1983 the present Research Co-ordination Programme (CRP) with a duration of five years. The report includes detailed results obtained by all participants as well as novel preparation procedures for some ...

1988-09-12

128

What Do We Feed to Food-Production Animals? A Review of Animal Feed Ingredients and Their Potential Impacts on Human Health

Hematopoietic stem cells (HSCs) have remained at the forefront of stem cell research for the past 50 years, since the therapeutic potential of bone marrow transplantation was realized. Uniquely, among stem and progenitor cells, research progress has been made in parallel between the laboratory benchtop and hospital bedside during this period. Integral to this work has been the role of the transfusion medicine services in the collection, storage, and processing of HSCs. The next decade promises to bring further developments: with new fields of cellular therapies, stem cell vaccination, and stem cell drug testing opening up. This article summarizes exciting areas of research concerning the behavior and potential clinical applications of HSCs. For the purposes of clarity, we describe in turn the trafficking and transfer of HSCs; ex vivo expansion of HSC units from different sources; and finally, applications of specifically selected subsets of ...

2011-09-01

129

WILD PIGS: BIOLOGY, DAMAGE, CONTROL TECHINQUES AND MANAGEMENT

ObjectiveAnimal feeding practices in the United States have changed considerably over the past century. As large-scale, concentrated production methods have become the predominant...Full Text Available

2007-05-01

130

Status of lead and bismuth for radioimmunoimaging and radioimmunotherapy

The existence of problems with wild pigs (Sus scrofa) is nothing new to the Western Hemisphere. Damage by these introduced animals was reported as far back as 1505 by the early Spanish colonies in the Caribbean, where wild pigs were killing the colonists cattle. Droves of these animals also ravaged cultivated crops of maize and sugarcane on islands in the West Indies during this same time period. These wild pigs reportedly were very aggressive and often attacked Spanish soldiers hunting rebellious Indians or escaped slaves on these islands, especially when these animals were cornered. The documentation of such impacts by introduced populations of this species in the United States has subsequently increased in recent years, and continued up through the present (Towne and Wentworth. 1950, Wood and Barrett 1979, Mayer and Brisbin 1991, Dickson et al. 2001). In spite of a fairly constant history in this country since the early ...

2009-12-31

131

Prospective cognition in animals.

Tumor-targeted monoclonal antibodies (mAb) might be useful as diagnostic or therapeutic agents when linked to cytotoxic or imaging reagents. Our group is working to test this hypothesis by linking cytocidal and image-producing isotopes to mAb and testing the utility of the radioimmunoconjugates formed in animal model systems. Radioiodines were first employed for these purposes,but unfavorable nuclear properties (half-lives, #gamma#-ray and #beta#-particle energies) and chemical reactivity (deiodination in vivo) limit their utility. Labeling immunoproteins with metallic radionuclides offers more versatility in that the selection of potentially useful radiometals spans the periodic table.Of the metallic radionuclides with physical properties most suited for use with mAb in nuclear medicine, few are more available or desirable than those of bismuth ("2"1"2Bi) and lead ("2"0"3Pb, "2"1"2Pb), as listed in Table 1. "2"1"2Bi or "2"1"2Pb could serve as ...

1990-08-26

132

Pitch discrimination by ferrets for simple and complex sounds

The debate about whether or not animals have foresight has focused on whether animals can be shown to have episodic future thinking, that is the ability to travel mentally in time and see themselves in the future. This focus has distracted from consideration of other forms of foresight that animals demonstrate. We propose a framework for examining future-oriented behaviours and then discuss the evidence for future thinking in animals. In the final section we examine some perspectives of future thinking and suggest that there are future-oriented capabilities of animals that do not involve mental time travel but may yet involve future thinking which deserve further investigation. PMID:20522320

2009-03-01

133

A Dose- and Time-Controllable Syngeneic Animal Model of Breast Cancer Microcalcification

Although many studies have examined the performance of animals in detecting a frequency change in a sequence of tones, few have measured animals' discrimination of the fundamental frequency...Full Text Available

2009-09-01

134

Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats, India

IntroductionThe development of novel diagnostic agents for the detection of breast cancer microcalcifications requires a reliable animal model. Based on previous...Full Text Available

2010-07-01

135

British Library Electronic Table of Contents (United Kingdom)

Ethnopharmacological relevance: For thousands of years, medicinal plants have played an important role throughout the world in treating and preventing a variety of diseases. Kani tribal people in Tirunelveli hills still depend on medicinal plants and most of them have a general knowledge of medicinal plants which are used for first aid remedies, to treat cough, cold, fever, headache, poisonous bites and some simple ailments. Aim of the study: The present study was initiated with an aim to identify traditional healers who are practicing herbal medicine among the Kani tribals in Tirunelveli hills of Western Ghats, India and quantitatively document their indigenous knowledge on the utilization of medicinal plants particularly most common ethnomedicinal plants. Methods: Field study was carried...

2011-01-01

136

The relationship of urinary metabolites of carbaryl/naphthalene and chlorpyrifos with human semen quality.

Technology development, evaluation, and application (TDEA) FY 1997 progress report

Most of the general population is exposed to carbaryl and other contemporary-use insecticides at low levels. Studies of laboratory animals, in addition to limited human data, show an association between carbaryl exposure and decreased semen quality. In the present study we explored whether environmental exposures to 1-naphthol (1N), a metabolite of carbaryl and naphthalene, and 3,5,6-trichloro-2-pyridinol (TCPY), a metabolite of chlorpyrifos and chlorpyrifos-methyl, are associated with decreased semen quality in humans. Subjects (n=272) were recruited through a Massachusetts infertility clinic. Individual exposures were measured as spot urinary concentrations of 1N and TCPY adjusted using specific gravity. Semen quality was assessed as sperm concentration, percent motile sperm, and percent sperm with normal morphology, along with sperm motion parameters (straight-line velocity, curvilinear velocity, and linearity). Median TCPY and 1N ...

2004-12-01

137

Inventory of tritium concentration of waters in the Manche department; Inventaire des concentrations en tritium des eaux du Departement de La Manche

The public expects that the Los Alamos National Laboratory (LANL) will operate in a manner that prevents negative impacts to the environment and protects the safety and health of its employees and the public. To achieve this goal within budget, the Department of Energy (DOE) and LANL must develop new and improved environment, safety, and health (ES and H) technologies and implement innovative, more cost-effective ES and H approaches to operations. In FY95, the Environment, Safety, and Health (ESH) Division initiated a Technology Development, Evaluation, and Application (TDEA) program. The purpose of this unique program is to test and develop technologies that solve LANL ES and H problems and improve the safety of LANL operations. This progress report presents the results of 10 projects funded in FY97 by the TDEA Committee of the Environment, Safety, and Health Division. Products generated from the projects funded in FY97 included implementation of radiation worker ...

1998-05-01

138

In vivo effects of cadmium chloride on certain aspects of carbohydrate metabolism in the tissues of a freshwater field crab Barytelphusa guerini

For the inventory of water tritium concentration in the Manche department, it is the complementarity that animated the work opened during year 2001. To answer to a commune sensitivity such water quality, particularly drinking water at tap, the A.C.R.O. laboratory brought its know how to make and its technical means in the area of tritium analysis and the general council brought its know how to make and its logistics means in matter of sanitary control. This collaboration has allowed to supply an indication on the tritium content of the distribution waters of thirty of the most important cities of the department. Then, it allowed to inform on the radiological situation (in relation with the tritium presence) of coast waters and principal rivers waters. More than 160 controls have been realised between the months of march 2001 and february 2002. Only the tritium under the shape of tritiated water has been measured. The measures have been made by ...

2007-07-01

139

Excess of seminomas observed in Vietnam service U.S. military workingn> dogs.

Cadmium is a toxic, non-essential heavy metal inhibiting numerous enzymes with functional sulfhydryl groups. Among the animals, aquatic organisms are most sensitive to heavy metals. Various aspects of toxic effects of cadmium pollution on fishes have been extensively reviewed. Survey of literature reveals that relatively few attempts have been made on the various aspects of cadmium toxicity in crustaceans and these studies were mainly devoted to marine forms. The freshwater crustaceans, particularly the freshwater field crab, Barytelphusa guerini, received less attention. This crab forms one of the major components of the paddy field ecosystem and has an edible importance among local populations. Apart from this, these crabs are easily available, maintainable in the laboratory and data obtained in this study can be extrapolated to other crustaceans. The present study reports the influence of cadmium on certain aspects of carbohydrate metabolism ...

1989-06-01

140

A review of the studies on the wholesomeness of irradiated wheat, conducted at the National Institute of Nutrition, India

During the Vietnam War, US military working dogs served with their companion dog handlers in close proximity, sharing common exposures to war-related activity, many zoonotic infectious agents, chemical pesticides, phenoxy herbicides, and extensive use of therapeutic drugs. To gain insight into the effects of the Vietnam experience, we investigated the occurrence of neoplasms in military working dogs based on standard necropsy examination by the Armed Forces Institute of Pathology. We observed that these dogs experienced significant elevated risks for testicular seminoma and, independently, testicular dysfunction. Experimental evidence shows testicular dysfunction and impaired spermatogenesis in laboratory animals exposed to phenoxy herbicides, dioxin, or tetracycline, and antibiotic used extensively in military working dogs in Vietnam. Because an unexplained significant decrease in sperm quality in Vietnam veterans has been observed by the ...

1990-06-20

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141

A new visitor centre for CMS

The wholesomeness of irradiated wheat was investigated in a series of experiments involving several species of animals and a small number of children, at the National Institute of Nutrition in India. Our observations indicated some effects following the feeding of freshly irradiated wheat while no such changes were found in the groups fed either unirradiated or stored irradiated wheat. Also, there were no significant differences between the groups fed unirradiated and stored irradiated wheat. Based on these results, a recommendation had been made to the government that when subjected to irradiation, wheat should be stored for at least 3 months before considering it as safe for human consumption. Similar experiments conducted in an establishment of the Department of Atomic Energy in India indicated no undesirable effects, unlike those found in our studies, and this had led to the development of a serious controversy. In this paper, we have not only reviewed our ...

142

CERN Multimedia

At the inauguration of the new CMS visitor centre. The CMS experiment inaugurated a new visitor centre at its Cessy site on 14 June. This will allow the thousands of people who come to CERN each year to follow the construction of one the Laboratory's flagship experiments first-hand. CERN receives over 20,000 visitors each year. Until recently, many of them were taken on a guided tour of one of the LEP experiments. With the closure of LEP, however, trips underground are no longer possible, and the Visits' Service has put in place a number of other itineraries (Bulletin 46/2000). Since the CMS detector will be almost entirely constructed in a surface hall, it is now taking a big share of the limelight. The CMS visitor centre has been built on a platform overlooking CMS construction. It contains a set of clear descriptive posters describing the experiment, along with a video projection showing animations and movies about CMS construction. In the ...

2001-01-01

143

Use of complementary and alternative medicines for children with chronic health conditions in Lagos, Nigeria

Polyphenols in the active fraction of needle-prick (Dasyphyllum brasiliense, Asteraceae), a medicinal plant with antiinflammatory activity; Polifenois na fracao ativa de espinho-agulha (Dasyphyllum brasiliense, Asteraceae), uma planta medicinal com atividade antiinflamatoria

BackgroundThe use of complementary and alternative medicine (CAM) is on the increase globally with a high prevalence in children and adults with chronic illnesses. Many studies have...Full Text Available

144

Patient organisations and the reimbursement process for medicines: an exploratory study in eight European countries

No abstract prepared.

2008-07-01

145

Is There a Role for Patent Medicine Vendors in Tuberculosis Control in Southern Nigeria?

BackgroundLittle is known about the role European patient organisations play in the process of deciding on reimbursement for medicines. Therefore we explore the...Full Text Available

146

Huo-Luo-Xiao-Ling Dan modulates antigen-directed immune response in adjuvant-induced inflammation

Patent medicine vendors (PMVs) are a ubiquitous feature of the informal health sector in Nigeria. A previous study on healthcare-seeking behaviour of persons with chronic cough in southern Nigeria found...Full Text Available

2010-12-01

147

Health professionals rarely record history of complementary and alternative medicines

Ethnopharmacological relevanceHLXL is a traditional Chinese medicine that has long been used in folk medicine for the treatment of chronic inflammatory diseases....Full Text Available

2009-05-04

148

Ethnomedicine in Himalaya: a case study from Dolpa, Humla, Jumla and Mustang districts of Nepal

AimsTo identify the completeness of documentation of Complementary And Alternative Medicine (CAM) use in hospital medical records of patients before and after an education programme.Full Text Available

2005-02-01

149

Early metabolism evaluation making traditional Chinese medicine effective and safe therapeutics*

Traditional plant use in Nepal has been documented for millennia. The importance of plants as medicine has not diminished in any way in recent times, and traditional medicines are still the most important...Full Text Available

150

Desired Chinese medicine practitioner capabilities and professional development needs: a survey of registered practitioners in Victoria, Australia

Increasing attention is being paid to the scientific evaluation of traditional Chinese medicine (TCM). As many TCMs are capable of biotransformation in the gastrointestinal tract, attention to biotransformation...Full Text Available

2006-02-01

151

Biology and Medicine Division annual report, 1978-1979

BackgroundThe State of Victoria in Australia introduced Chinese medicine practitioner registration in 2000 and issued its education guidelines in late 2002 for introduction in 2005....Full Text Available

152

Anticancer effects of Chinese herbal medicine, science or myth?*

Summaries of research projects conducted during 1978 and 1979 are presented. Subject areas include research medicine, cancer research, environmental physiology, radiation biophysics, and structural biophysics. (ACR)

1979-01-01

153

[ ${\\alpha}$ ]-Amylase and Protein Tyrosine Phosphatase 1B Inhibitory of Some Vietnamese Medicinal Plants Used to Treat Diabetes

Currently there is considerable interest among oncologists to find anticancer drugs in Chinese herbal medicine (CHM). In the past, clinical data showed that some herbs possessed anticancer properties,...Full Text Available

2006-12-01

154

ProteoChip-based Library Screening of Integrin ${\\alpha}5{\\beta}1$ Antagonists from Korean Medicinal Plant Extracts

Full Text Available

2007-12-01

155

Neuroprotective Activities of Some Medicinal Plants against Glutamate-induced Neurotoxicity in Primary Cultures of Rat Cortical Cells

Full Text Available

2007-12-01

156

Leaf Ontogenic Phase-Related Dynamics of Withaferin A and Withanone Biogenesis in Ashwagandha (Withania somnifera Dunal.) - An Important Medicinal Herb

Full Text Available

2009-09-01

157

Inhibitory Effects of Methanolic Extracts of Medicinal Plants on Nitric Oxide Production in Activated Macrophage RAW 264.7 Cells

Full Text Available

2007-08-01

158

Effects of Supplemental Medicinal Plants (Artemisia, Acanthopanax and Garlic) on Productive Performance of Sows and on Growth and Carcass Traits in Finishing Pigs

Full Text Available

2009-06-01

159

Effect of Supplemental Medicinal Plants(Artemisia, Acanthopanax and Garlic) on Growth Performance and Serum Characteristics in Lactating Sows, Suckling and Weanling Pigs

Full Text Available

2010-04-01

160

Effect of Medicinal Plant Water Extracts on Glucose-regulating Enzyme Activities in Goto-Kakizaki Rat Liver Cytosol

Full Text Available

2005-08-01

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161

Effect of Garlic and Medicinal Plants Composites on the Liver Function and Lipid Metabolism of Rats Administered with Ethanol During the Short-term

Full Text Available

2009-10-01

162

Comparison of Hydroxyl Radical, Peroxyl Radical, and Peroxynitrite Scavenging Capacity of Extracts and Active Components from Selected Medicinal Plants

Full Text Available

2009-07-01

163

Arabinogalactans isolated from the medicinal plant Maytenus ilicifolia

Full Text Available

2010-12-01

164

Visible Earth: Typhoon Aere

English 2006 [1 p.] Brazil Cipriani, TR Mellinger, CG Gorin, PAJ Sassaki,

2006-07-01

165

Study on the Development of Solid Fuel of Animal Wastes for Heating of Agricultural Facilities

NASA's Visible Earth catalog of NASA images and animations of our home planet.

166

Full Text Available

2007-10-01

167

NAME=\\

...Assemblages of plants and invertebrate animals of tumulus (organic mound) springs of the Swan Coastal Plain Assemblages of plants and invertebrate animals of tumulus ...organic mound) springs of the Swan Coastal Plain [Skip navigation links] About us | Contact us | Publications |...ecological communities Assemblages of plants and invertebrate animals of tumulus (organic mound) springs of the Swan Coastal Plain Advice to the Minister for the ...of the 'Assemblages of plants and invertebrate animals of tumulus (organic mound) springs of the Swan Coastal Plain' community sufficient to distinguish it from ...

168

Creative Australia

Animal Brucellosis in the Kyrgyz Republic

animation The structure of the creative industries is changing Previously there were small numbers of producers and a

169

Faculties :: University of Southampton

Epizootological Monitoring of Brucellosis and Methods of its Eradication in the Kyrgyz Republic

170

Evolution of health information management and information technology in emergency medicine.

...Modern Languages Music Philosophy Faculty of Medicine Faculty of Medicine page Academic unit: Medicine Faculty of Natural and Environmental Sciences Faculty of Natural and Environmental Sciences page Academic units: Biological Sciences Chemistry National Oceanography Centre, Southampton Ocean and Earth Science Faculty of Physical and Applied Sciences Faculty of Physical and Applied Sciences page Academic units: Electronics and Computer Science Optoelectronics Research Centre Physics and Astronomy Faculty of Social and Human Sciences ...

171

Effects of gamma irradiation on physiological effectiveness of Korean medicinal herbs

The implementation of information technology will continue to have important effects on the practice of emergency medicine. Patient registration and tracking systems, telemedicine electronic order entry systems, and the advent of electronic health records are some examples of applications that influence patient care in emergency departments. We review the literature regarding information technology advances in emergency medicine and outline the important role that emergency physicians play in developing and implementing a national health information technology strategy. PMID:16712540

2006-06-01

172

Effects of gamma irradiation on microbial contamination and extraction yields of Korean medicinal herbs

Effects of gamma irradiation on the physiological effectiveness of Korean medicinal herbs were investigated. The physiological effectiveness including antioxidant and anticomplement function, nitrite scavenging and electron donating ability of Korean medicinal herbs by gamma irradiation at 10 kGy did not differ from that of the nonirradiated control.

1999-03-01

173

Undergraduate teaching of nuclear medicine: a comparison between Central and Eastern Europe and European Union countries

Effects of gamma irradiation on hygienic quality and extraction yields in twenty-one kinds of Korean medicinal herbs were investigated. Gamma irradiation at 5-10 kGy inactivated contaminating microorganisms. The total extraction yield in fifteen kinds of the investigated medicinal herbs increased by 5-25% by a dose of 10 kGy. (author)

2000-01-01

174

University of Central Lancashire - Facilities

This paper overviews the curricula of nuclear medicine (NM) undergraduate training in 34 Central and Eastern European (CEE) and 37 European Union (EU) medical faculties. The data show enormous variation in the number of hours devoted to nuclear medicine, varying between 1-2 to 40 hours and highly differentiated concepts/ideas of nuclear medicine training in particular countries. In most EU countries this teaching is integrated with that of radiology or clinical modules, also with training in clinical physiology. In many CEE countries teaching and testing of NM are independent, although integration with other teaching modules is frequent. The paper discusses the differences in particular approaches to nuclear medicine teaching. (author)

175

[Medicine and truth: between science and narrative].

...specialised laboratories for pharmaceutics, tissue culture and molecular biology Excellent Laboratory Facilities Tissue Culture Facilities Molecular Biology Laboratory ...

176

[The possibilities for the laboratory diagnosis of schizophrenia].

To which idea of truth may medicine refer? Evidence-based medicine (EBM) is rooted in the scientific truth. To explain the meaning and to trace the evolution of scientific truth, this article outlines the history of the Scientific Revolution and of the parable of Modernity, up to the arrival of pragmatism and hermeneutics. Here, the concept of truth becomes somehow discomfiting and the momentum leans towards the integration of different points of view. The fuzzy set theory for the definition of disease, as well as the shift from disease to syndrome (which has operational relevance for geriatrics), seems to refer to a more complex perspective on knowledge, albeit one that is less defined as compared to the nosology in use. Supporters of narrative medicine seek the truth in the interpretation of the patients' stories, and take advantage of the medical humanities to find the truth in words, feelings and contact with the ...

177

Emerging laboratory biosecurity issues.

PMID:2042311

1991-02-01

178

??????? ?????????(Applied Aerodynamics Laboratory)

No abstract prepared.

2005-04-01

179

Design of a new serotonin receptor 5-HT_1_A imaging agent based on "9"9"mTc

Full Text Available

2011-03-01

180

Clinical and ultrasonographic findings, diagnosis and treatment of pyelonephritis in 17 cows

Serotonin is one of the neurotransmitters found in the brain and mediates brain functions. It is very well known that serotonin related brain abnormalities are exerted mainly via serotonin receptors in a similar manner to other neurotransmitters found in the brain. Recently, it has also been found that serotonin is involved in Alzheimer's disease either directly or indirectly by its actions on serotonergic neurons. To understand and treat the diseases caused by abnormalities in the serotonergic system in the brain, it is certain that its mechanism of function has to be well investigated. So far several 5-HT receptors and receptor subtypes have been well characterized. Moreover, serotonin agonists and antagonists acting on specific receptors are chemically synthesized and are now available for the prevention or treatment of serotonergic related diseases. In recent years, a great demand for developing neuroimaging agents has emerged for the diagnosis of abnormal brain functions in the ...

2004-07-01

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181

British Library Electronic Table of Contents (United Kingdom)

The goal of the present study was to describe the clinical, haematological and ultrasonographic findings and treatment of 17 cattle with pyelonephritis. Fifteen cattle had an abnormal general condition, which varied in severity; five animals had signs of colic. The urine was brownish-red in 11 animals and cloudy in 13. Clumps of purulent material were seen in the urine of nine animals and clots of blood in two. The specific gravity was lower than normal in 13 animals and ranged from 1.005 to 1.020. A urine test strip revealed protein in 16 animals, blood in 16 and leukocytes in 12. Bacteriological examination of urine yielded Corynebacterium renale in 11 animals, Arcanobacter pyogenes in two and Escherichia coli in one. Rectal examination revealed abnormalities of the urinary tract in 11 a...

2008-01-01

182

Isotope Production at the Hanford Site in Richland, Washington

Gamma and X-ray shielding compositions utilizing bauxite - Red Mud regional research laboratory (CSIR), Bhopal, India

This report was prepared in response to a request from the Nuclear Energy Research Advisory Committee (NERAC) subcommittee on ''Long-Term Isotope Research and Production Plans.'' The NERAC subcommittee has asked for a reply to a number of questions regarding (1) ''How well does the Department of Energy (DOE) infrastructure sme the need for commercial and medical isotopes?'' and (2) ''What should be the long-term role of the federal government in providing commercial and medical isotopes?' Our report addresses the questions raised by the NERAC subcommittee, and especially the 10 issues that were raised under the first of the above questions (see Appendix). These issues are related to the isotope products offered by the DOE Isotope Production Sites, the capabilities and condition of the facilities used to produce these products, the management of the isotope production programs at DOE ...

1999-06-01

183

Universal model for water costs of gas exchange by animals and plants

Available in abstract form only. Full text of publication follows: The application spectrum of X-ray and Gamma radiation is increasing exponentially in the area of diagnostic, nuclear medicine, food preservation, nuclear power plants and strategic utilities. To prevent the harmful effects of these radiations, shielding materials based on lead metal and its compounds are being used historically, which are toxic in nature. To protect environment it has become necessary to develop non-toxic lead free shielding materials. The use of titanium metal and its compounds as synthetic rock i.e. SYNROC are reported to be very effective non-toxic shielding materials for various applications. Red mud waste generated in aluminum producing industries possesses a unique mineralogical compositions containing fairly high quantity of titanium oxide and iron oxide useful for making non toxic shielding compositions and therefore red mud has been utilized for the first time in the world ...

2007-09-02

184

Transmission of Salmonella mbandaka to cattle from contaminated feed.

For terrestrial animals and plants, a fundamental cost of living is water vapor lost to the atmosphere during exchange of metabolic gases. Here, by bringing together previously developed models for...Full Text Available

2010-05-04

185

Specific genetic modifications of domestic animals by gene targeting and animal cloning

Salmonella mbandaka was isolated from cattle on three dairy farms. The duration of infection was less than four weeks and none of the animals became clinically ill. The animals had all consumed a diet...Full Text Available

1982-04-01

186

Mycotoxins in fungal contaminated samples of animal feed from western Canada, 1982-1994.

The technology of gene targeting through homologous recombination has been extremely useful for elucidating gene functions in mice. The application of this technology was thought impossible in the large...Full Text Available

187

Molecular determinants archetypical to the phylum Nematoda

Feed samples from 94 cases involving fungal contamination and suspected mycotoxicosis of farm animals in western Canada were examined during 1982-1994 to assess the incidence of mycotoxins. Samples...Full Text Available

1997-01-01

188

Isolation of an Escherichia coli K4 kfoC mutant over-producing capsular chondroitin

BackgroundNematoda diverged from other animals between 600–1,200 million years ago and has become one of the most diverse animal phyla on earth. Most nematodes are free-living...Full Text Available

189

From spectral information to animal colour vision: experiments and concepts

BackgroundChondroitin sulphate is a complex polysaccharide having important structural and protective functions in animal tissues. Extracted from animals, this compound is used as...Full Text Available

190

Distribution, Frequency, and Diversity of Bacillus thuringiensis in an Animal Feed Mill

Many animals use the spectral distribution of light to guide behaviour, but whether they have colour vision has been debated for over a century. Our strong subjective experience of colour and the fact...Full Text Available

2010-06-07

191

Development Document for Proposed Effluent Limitations Guidelines and Standards for the Concentrated Aquatic Animal Production Industry Point Source Category.

Bacillus thuringiensis was isolated from 36 of 50 residue samples obtained from an animal feed mill (a stored-product environment). Of 710 selected colonies having Bacillus...Full Text Available

1992-04-01

192

Components of change in the evolution of learning and unlearned preference

This section presents background information supporting the development of effluent limitations guidelines and standards for the concentrated aquatic animal production (CAAP) point source category. Section 1.1 presents the legal authority to regulate the ...

2002-01-01

193

Comparative aspects of pesticide metabolism in plants and animals.

Several phenomena in animal learning seem to call for evolutionary explanations, such as patterns of what animals learn and do not learn. While several models consider how evolution should influence...Full Text Available

2009-09-07

194

Comparative and alternative approaches and novel animal models for aging research

Pesticide chemicals are an important component of modern agriculture. Through their use, plants and animals are exposed to pesticides directly and indirectly from transport through soil, water, and...Full Text Available

1978-12-01

195

Antinociceptive and Anti-Inflammatory Activities of the Ethanol Extract of Annona muricata L. Leaves in Animal Models

This special issue of AGE showcases powerful alternative or unconventional approaches to basic aging research, including the use of exceptionally long-lived animal model species and...Full Text Available

2008-09-01

196

Animal models of human amyloidoses: Are transgenic mice worth the time and trouble?

Antinociceptive and anti-inflammatory activities of the ethanol extract from Annona muricata L. leaves were investigated in animal models. The extract delivered per oral route (p.o.)...Full Text Available

197

Amazon Deforestation Model

The amyloidoses are the prototype gain of toxic function protein misfolding diseases. As such, several naturally occurring animal models and their inducible variants provided some of the first...Full Text Available

2009-08-20

198

A Serological Survey of Sera from Domestic Animals on Easter Island

This series of animations depicts the results of a computer simulation of the effects of deforestation on the surface temperature and precipitation in the Amazon region. Six animations are shown - a control simulation, a deforestation simulation, and the difference between the two for both surface temperature and rainfall. The period simulated is the second half of 1987.

1994-03-13

199

Visible Earth: Food Additives

Animals' sera collected on Easter Island from December 1964 to February 1965 were tested by appropriate methods for the presence of antibodies to various infections. These included, ornithosis, Q-fever,...Full Text Available

1968-04-01

200

Development of QTL Mapping Populations

Feb 25, 2008 ... NASA's Visible Earth catalog of NASA images and animations of our home planet.

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201

Sunscreen

Medline Plus

... Animal & Veterinary Cosmetics Radiation-Emitting Products Tobacco Products Drugs Home > Drugs > Resources for You > Information for Consumers (Drugs) Section ...

202

The use of x-ray fluorescence in the detection of inorganic elements in medicines drugs

The objective of this animation is to develop a QTL mapping population for locating and characterizing the genes responsible for resistance to tan spot disease of wheat.

203

Clinical magnetic resonance imaging with nuclear medicine correlation

Based on the instrumental wavelength dispersive X-ray fluorescence technique of analysis (W D-X R F), the inorganic elements in four samples of commercial medicines drugs were analyzed. The samples were used without any chemical separation of the elements or chemical pre-treatment. Eleven elements could be identified, namely Si, P, S, Cl, K, Ca, Ti, Mn, Fe, Cu and Zn. However, Si, Ti and Mn have not been mentioned in the printed instructions for the use of the medicines drugs by the producers. (author)

204

Traditional Medicine in Oman: Its Role in Ophthalmology

The current role of magnetic resonance imaging (MRI) in different organ systems is discussed and compared to nuclear medicine and to other available clinical diagnostic modalities. The value of optimizing radiofrequency pulse sequence selection to provide additional tissue characterization is also described. The results of nuclear medicine and MRI studies in 56 patients are compared to evaluate the clinical diagnostic contribution of each imaging modality for various pathological processes. In addition, the state-of-the-art MRI systems and future development in MRI technology with its potential contribution is defined.

1985-08-01

205

Traditional Medicine Collection Tracking System (TM-CTS): A database for ethnobotanically driven drug-discovery programs

Aim:To present three patients with ocular disease who developed a range of complications following use of traditional medications.Settings...Full Text Available

2009-04-01

206

British Library Electronic Table of Contents (United Kingdom)

Ethnopharmacological relevance: Ethnobotanically driven drug-discovery programs include data related to many aspects of the preparation of botanical medicines, from initial plant collection to chemical extraction and fractionation. The Traditional Medicine Collection Tracking System (TM-CTS) was created to organize and store data of this type for an international collaborative project involving the systematic evaluation of commonly used Traditional Chinese Medicinal plants. Materials and methods: The system was developed using domain-driven design techniques, and is implemented using Java, Hibernate, PostgreSQL, Business Intelligence and Reporting Tools (BIRT), and Apache Tomcat. Results: The TM-CTS relational database schema contains over 70 data types, comprising over 500 data fields. Th...

2011-01-01

207

The informationist: building evidence for an emerging health profession*

The developmental anatomy using MRI. The structural change of the brain development in children. The perianterior horn of lateral ventricle

Background:To encourage evidence-based practice, an Annals of Internal Medicine editorial called for a new professional on clinical teams: an informationist trained...Full Text Available

2010-04-01

208

The Potential Risks of Commonly Prescribed Antipsychotics

Japanese ... Authors Utsunomiya, Hidetsuna (Fukuoka Univ. (Japan). School of Medicine); Nakamura, Yasuhiro

1999-10-01

209

Systems medicine: the future of medical genomics and healthcare

Chlorpromazine, haloperidol, fluphenazine, clozapine, risperidone, quetiapine, olanzapine, ziprasidone, and aripiprazole are antipsychotics commonly used in psychiatric medicine. Approximately one third...Full Text Available

210

Study of some Ayurvedic Indian medicinal plants for the essential trace elemental contents by instrumental neutron activation analysis and atomic absorption spectroscopy techniques

High-throughput technologies for DNA sequencing and for analyses of transcriptomes, proteomes and metabolomes have provided the foundations for deciphering the structure, variation and function of the...Full Text Available

211

Somatic effects in nuclear medicine and radiology

Elemental analysis of some medicinal plants used in the Indian Ayurvedic system was performed by employing instrumental neutron activation analysis (INAA) and atomic absorption spectroscopy (AAS) techniques. The samples were irradiated with thermal neutrons in a nuclear reactor and the induced activity was counted by gamma ray spectrometry using an efficiency calibrated high resolution high purity germanium (HPGe) detector. Most of the medicinal plants were found to be rich in one or more of the elements under study. The variation in elemental concentration in same medicinal plants samples collected in summer, winter and rainy seasons was studied and the biological effects of these elements on human beings are discussed. (orig.)

2009-07-01

212

Serving in Haiti: Perspective of a Physician

Probable risks for the occurrence of somatic effects due to diagnostic radiology and nuclear medicine are summarised. The biological background of radiation carcinogenesis and epidemiological results are discussed. At the Leiden University Medical Centre the average effective dose per examination due to diagnostic radiology and nuclear medicine amount to 0.95 and 4.4 mSv, respectively. These values correspond well with the average values of 0.82 and 3.0 mSv reported for The Netherlands as a whole. Since radiological examinations are performed at a much larger frequency than nuclear medicine the relative collective dose for the first type of examinations is higher than the latter. Risk for occurency of malignancies are at least one order of magnitude lower than the hypothetical risk due to the background radiation typical of The Netherlands.

1999-01-01

213

Nuclear medicine and imaging research. Progress report, January 1, 1980-December 31, 1980. [Lead Abstract

In the wake of the 2010 earthquake in Haiti, medical relief organizations and individual practitioners mobilized to provide assistance. Here, an emergency medicine physician who worked with a Louisiana-based...Full Text Available

2011-01-01

214

Model for assessing psychosocial problems.

Separate abstracts were prepared for the 5 subprojects designated as projects 1 to 4 and 6 in this progress report. (KRM)

1980-09-01

215

Metronidazole to prevent preterm delivery in pregnant women with asymptomatic bacterial vaginosis. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units.

The Model for the Assessment of Psychosocial Problems (MAPP) can help family medicine residents effectively assess patients with psychosocial problems. Following a patient-centred clinical method, MAPP...Full Text Available

1996-02-01

216

Immune Alteration Studies in Irradiated Dogs.

PMID:10684911

2000-02-24

217

Extraction of Cs-137 by alcohol-water solvents from plants containing cardiac glycosides

... objective of this research work were to 1 ... function of experimentally manipulated dogs to define ... Escherichia coli; Sepsis; Military medicine; Medical ...

1986-10-31

218

CERN Document Server

As a result of nuclear power plant accidents, large areas receive radioactive inputs of Cs-137. This cesium accumulates in herbs growing in such territories. The problem is whether the herbs contaminated by radiocesium may be used as a raw material for medicine. The answer depends on the amount of Cs-137 transfered from the contaminated raw material to the medicine. We have presented new results of the transfer of Cs-137 from contaminated Digitalis grandiflora Mill. and Convallaria majalis L. to medicine. We found that the extraction of Cs-137 depends strongly on the hydrophilicity of the solvent. For example 96.5%(vol.) ethyl alcohol extracts less Cs-137 (11.6%) than 40%(vol.) ethyl alcohol or pure water (66.2%). The solubility of the cardiac glycosides is inverse to the solubility of cesium, which may be of use in the technological processes for manufacturing ecologically pure herbal medicine.

2001-01-01

219

Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis

Emergency medicine in Oman: current status and future challenges

The rapidly emerging science of epigenetics and epigenomic medicine promises to reveal novel insights into the susceptibility to and the onset and progression of epileptic disorders. Epigenetic...Full Text Available

2010-07-01

220

British Library Electronic Table of Contents (United Kingdom)

The Sultanate of Oman has a relatively young national health care system that could demonstrate its high performance at an international level. Emergency medicine as a specialty has developed rapidly in the country over the last decade. This has involved the parallel development of local emergency residency training, prehospital emergency care, and emergency nursing programs. This article reviews the progress of emergency care practice in this country from a general primary care system toward becoming an established specialty in hospital, prehospital, and private emergency care settings. It also describes aspects of undergraduate, postgraduate, and continuous emergency medicine education in the country. Further, a glimpse into academic emergency medicine and emergency nursing is provided. ...

2009-01-01

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221

Disability rates of bus drivers

Creating reliable pharmaceutical distribution networks and supply chains in African countries: Implications for access to medicines

Raffle, P. A. B. (1974).British Journal of Industrial Medicine,31, 152-158. Disability rates of bus drivers. The proposal that ordinary driving...Full Text Available

1974-04-01

222

British Library Electronic Table of Contents (United Kingdom)

The presence of inefficient distribution networks and supply chains of medicines creates problems in that even if African countries can secure steep, sustainable cost-containing procurements, access to needed medicines may still be impaired. The expected health benefits from affordable pricing or subsidies on prices of medicines may not be realized. This article evaluates drug supply chains in African countries and advocates for consolidated private wholesale markets and multiplicity of retail pharmacies. Public supply chains should be shortened and supported by contracting out with private distributors, including wholesalers and retail pharmacies. Additionally, drug regulatory authorities should be allowed to charge registration fees that are proportionate to the costs of technical regula...

2009-01-01

223

Comparison of methods to determine accurate dose calibrator activity measurements

CDC - Injury - FOA CE01-015

BackgroundIn nuclear medicine, liquid radiopharmaceuticals for diagnostic or therapeutic purposes are administered to patients by using various types of syringes with different volumes....Full Text Available

224

Browse Conditions - Genetics Home Reference

of injuries, disabilities, and deaths; and 3. Encourage professionals from a wide spectrum of disciplines such as engineering, bioengineering, medicine, health care, public...

2011-08-20

225

Antibacterial potential of the extracts derived from leaves and in vitro raised calli of medicinal plants Pterocarpus marsupium Roxb., Clitoria ternatea L., and Sanseveiria cylindrica Bojer ex Hook

Home A service of the U.S. National Library of Medicine® Home Conditions Genes Chromosomes Handbook Glossary Resources Genetic Conditions > Browse Conditions 1-9 | A | B | C...

2011-09-24

226

A Comparison of Chinese and American Indian (Chumash) Medicine

Full Text Available

2009-06-01

227

Chinese and Chumash traditional medical approaches are similar in terms of disease causation, use of acupuncture or healing touch, plants, spiritual and philosophical approaches. This article provides...Full Text Available

2010-06-01

228

Clinical and ultrasonographic findings, diagnosis and treatment of pyelonephritis in 17 cows.

Instructions and control measures related to enteric contagious diseases at the Veterinary Medical Teaching Hospital (VMTH) of the Faculty of Veterinary Medicine of the University of Montreal are presented....Full Text Available

1999-12-01

229

Species comparison of acute inhalation toxicity of ozone and phosgene

The goal of the present study was to describe the clinical, haematological and ultrasonographic findings and treatment of 17 cattle with pyelonephritis. Fifteen cattle had an abnormal general condition, which varied in severity; five animals had signs of colic. The urine was brownish-red in 11 animals and cloudy in 13. Clumps of purulent material were seen in the urine of nine animals and clots of blood in two. The specific gravity was lower than normal in 13 animals and ranged from 1.005 to 1.020. A urine test strip revealed protein in 16 animals, blood in 16 and leukocytes in 12. Bacteriological examination of urine yielded Corynebacterium renale in 11 animals, Arcanobacter pyogenes in two and Escherichia coli in one. Rectal examination revealed abnormalities of the urinary tract in 11 animals; there was dilatation of the left ureter ...

2007-03-23

230

Species comparison of acute inhalation toxicity of ozone and phosgene

A comparison of the concentration-response effects of inhaled ozone (O/sub 3/) in different species of laboratory animals was made in order to better understand the influence of the choice of species in inhalation studies of this gas. The effect of 4-hour exposure to ozone (O/sub 3/) at concentrations of 0.0, 0.2, 0.5, 1.0, and 2.0 ppm was determined in rabbits, guinea pigs, rats, hamsters and mice. Lavage fluid protein (LFP) accumulation 18 hr after exposure was used as the indicator of O/sub 3/-induced pulmonary edema. All species had similar basal levels of LFP (250-350 ug/ml) when a volume of saline which approximated the total lung capacity was used for lavage of the collapsed lungs. Exponential dose-response curves were seen in all species except guinea pigs, which showed significant increases in LFP at low O/sub 3/ concentrations (0.2 ppm) and a leveling off of response at the higher O/sub 3/ levels. Other species usually showed ...

1986-01-01

231

Comparison of bone cancer risks in beagle dogs for inhaled plutonium-238 dioxide, inhaled strontium-90 chloride, and injected strontium-90

A comparison of the concentration-response effects of inhaled ozone (O/sub 3/) and phosgene (COCl/sub 2/) in different species of laboratory animals was made in order to better understand the influence of the choice of species in inhalation toxicity studies. The effect of 4-h exposures to ozone at concentrations of 0.2, 0.5, 1.0, and 2.0 ppm, and to COCl/sub 2/ and 0.1, 0.2, 0.5, and 1.0 ppm was determined in rabbits, guinea pigs, rats, hamsters, and mice. Lavage fluid protein (LFP) accumulation 18-20 h after exposure was used as the indicator of O3- and COCl/sub 2/-induced pulmonary edema. All species had similar basal levels of LFP (250-350 mg/ml) when a volume of saline that approximated the total lung capacity was used to lavage the collapsed lungs. Ozone effects were most marked in guinea pigs, which showed significant effects at 0.2 ppm and above. Mice, hamsters, and rats showed effects at 1.0 ppm O3 and above, while rabbits responded ...

1986-01-01

232

Radiation hazards from medical applications

There is a continuing need to understand dose-response relationships for ionizing radiation in order to protect the health of the public and nuclear workers from undue exposures. However, relatively few human populations have been exposed to doses of radiation high enough to cause observable, long-term health effects from which to derive dose-response relationships. This is particularly true for internally deposited radionuclides, although much effort has been devoted to epidemiological studies of the few types of exposures available, including lung cancers in uranium miners form the inhalation of the radioactive decay products of Ra, liver cancers in patients injected with Thorotrast X-ray contrast medium containing Th, bone cancers in radium dial painters who ingested Ra, and bone cancers in patients who received therapeutic doses of Ra. These four types of exposures to internally deposited radionuclides provide a basis for understanding the health effects of many other radionuclides ...

1995-12-01

233

Non-Linear Dose-Response Relationships in Biology, Toxicology and Medicine - An International Conference

An introduction is presented on the radiation hazards connected with biomedical radiography and nuclear medicine. The frequency of radiodiagnostic efforts was rather high in the Netherlands. This was reduced considerably by abolishing the thorax screening of the population. About diagnostic nuclear medicine less can be said because far fewer numerical data are available. An exposition of genetically and somatically significant doses and how to compute them is given. The drawing up of a profit versus risk evaluation for medical applications of ionizing radiations is recommended. (Auth.).

1980-05-31

234

Introduction to the special issue on decision support in medicine

Conference abstract book contains seven sections: Plenary-4 abstracts; Chemical-9 abstracts; Radiation-7 abstracts; Ultra Low Doses and Medicine-6 abstracts; Biomedical-11 abstracts; Risk Assessment-5 abstracts and Poster Sessions-25 abstracts. Each abstract was provided by the author/presenter participating in the conference.

2002-05-28

235

British Library Electronic Table of Contents (United Kingdom)

Information technology plays an important role in medicine because of the advanced decision support systems (DSS) it can provide. We provide an overview of the building blocks necessary for a medical decision support system and introduce seven research articles in this special issue that describe the development and evaluation of individual medical DSS building blocks or complete medical DSS.

2007-01-01

236

Heavy metals and some other elements in medicinal plants. Determined by X-ray fluorescence analysis

Development of solar agricultural dryers combined with PV modules and solar collectors

Determination of Mn, Fe, Cu, Zn, Hg, Pb, Br, Se, Rb, Sr and Cd in the medicinal plants by radionuclide X-ray fluorescence analysis (using "2"3"8Pu, "2"4"1Am/Ag and "1"2"5I) is described. (author). 12 refs., 2 tabs.

1995-01-01

237

Cultural narratives: bridging the gap. Educating speech-language pathologists to work in multicultural populations.

The intention of the research carried out was to develop photovoltaic driven solar heating systems applied for drying of medicinal plants in remote areas. Identification of hybrid photovoltaic - photothermal systems was done and discussion of technical features and applicability of such systems in agriculture is presented. Detail technical specification of PV powered medicinal plants solar dryer and cost effectiveness parameters are given. Operational and economic results obtained during testing of the dryer are promising. (orig.) 4 refs.

1997-12-31

238

Preparation of the clinician to work in multicultural contexts involves the identification of a range of skills, knowledge and values. The field of narrative medicine as well as an increased understanding of the dynamics of interpreting are areas which can add considerably to clinical effectiveness. The paper outlines some cornerstones of narrative medicine and their potential application to the field of speech-language pathology and audiology. PMID:12037426

239

NRL Fact Book 2010

... Tactical Electronic Warfare Division (Code 5700) Visualization Laboratory Transportable step frequency radar Vehicle development laboratory ...

2011-05-15

240

NRL Fact Book

Bioinformatics in the information age

... Tactical Electronic Warfare Division (Code 5700) Visualization Laboratory Transportable step frequency radar Vehicle development laboratory ...

2011-05-15

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241

Development of radioimmunometric assays and kits for non-clinical applications. Proceedings of a final research coordination meeting

There is a well-known story about the blind man examining the elephant: the part of the elephant examined determines his perception of the whole beast. Perhaps bioinformatics--the shotgun marriage between biology and mathematics, computer science, and engineering--is like an elephant that occupies a large chair in the scientific living room. Given the demand for and shortage of researchers with the computer skills to handle large volumes of biological data, where exactly does the bioinformatics elephant sit? There are probably many biologists who feel that a major product of this bioinformatics elephant is large piles of waste material. If you have tried to plow through Web sites and software packages in search of a specific tool for analyzing and collating large amounts of research data, you may well feel the same way. But there has been progress with major initiatives to develop more computing power, educate biologists about computers, increase funding, and set standards. For our ...

2000-02-01

242

Thermal basis for disruption of operant behavior by microwaves in three animal species

Immunoassays are versatile analytical techniques that had a leading role in various clinical applications, during the last four decades. The studies carried out by Rosalyn Yalow, Solomon Berson and Roger Ekins in the 1960s gave a breakthrough in the development of this novel analytical method. Sensitivity up to femtomolar concentrations, high specificity and universal application to different classes of molecular species made immunoassay a very useful tool in analytical investigation. The expertise acquired by immunochemists in producing antibodies against any antigen and the ability of radiochemists in labeling the antigens with "1"2"5I without affecting the active site are the two main factors responsible for the above development. There are concerns about the safety and health of humans due to the high-level contamination of environment by pesticides, industrial compounds and metals, anabolic steroids in milk and meat products, and presence of mycotoxins in food and feed ...

2004-12-06

243

Organic farming in the Nordic countries--animal health and production.

A large variety of microwave producing devices are used in contemporary naval communications and weapons systems. Public and scientific concern about potential biological effects of microwave irradiation such as produced by these various devices requires documentations of such effects. Currently, the only well documented direct effect of microwaves is heating of the exposed organism. The present report is of a series of studies whose aim was to explore several microwave frequencies and their effect on performance and simultaneously to investigate the relationship to core heating in the exposed animals. Three difficult sized species of animals were used so that generalization to larger animals could be made. Rats, squirrel monkeys, and rhesus monkeys showed consistent effects of 60-minute exposures to microwaves when their body temperatures were increased at least 1 C above baseline temperatures. Performance was not reliably ...

1982-06-01

244

Influence of animal age upon antioxidant-modified UV carcinogenesis

Organic farming (or ecological agriculture) is of growing importance in the agricultural sector worldwide. In the Nordic countries, 1-10% of the arable land was in organic production in 1999. Organic farming can be seen as an approach to agriculture where the aim is to create integrated, humane, environmentally and economically sustainable agricultural production systems. Principles like nutrient recycling, prevention rather than treatment and the precautionary principle are included in aims and standards. Animal welfare is another hallmark of organic livestock production but despite this, several studies have indicated severe health problems e.g. in organic poultry production in Denmark. Also the quality of animal food products in relation to human health, particularly the risk of zoonotic infections, has been debated. For these reasons there is a need for improvement of production methods and animal health status. Vets ...

2001-01-01

245

Use of X-ray fluorescence analysis in the study of archeological samples

Studies were undertaken to examine the effects of animal age on the anticarcinogenic properties of antioxidants. Female hairless mice, 2.5, 4.5 and 9.5 months of age, were subjected to daily irradiation from Westinghouse BZS-WLG lamps for 19 weeks. Experimental groups of animals were maintained on a commercial rodent meal supplemented with a 2% (w/w) antioxidant mixture. Control groups received only the meal. Tumour latency, expressed as median time to tumor development, was significantly greater for all age groups receiving antioxidants than for their similarly aged controls. However, the response to antioxidants appeared to decrease with age and the antioxidant effect was significantly less in the 9.5 month-old group than in the 2.5 month-old group. Likewise, the two youngest groups receiving antioxidants demonstrated a significantly fewer number of tumors per animal. It is concluded that animal age ...

246

Removal of "2"3"9Pu from the rat with an orally administered chelon

Radionuclide X-ray fluorescence analysis (XFA) was used in the determination of the contents of metal residues in dosing plates for coin minting. XFA was also used for the determination of the strontium/calcium ratio in bone samples of different animals with the aim to obtain information on the food composition of these animals. It was found that bones of different animals can be distinguished based on the Sr/Ca ratio. No significant differences in the Sr/Ca ratio were observed in human bones of individuals from different social groups. (author). 1 fig., 5 tabs., 4 refs.

1988-09-26

247

Effect on the reproductive functions of female rhesus monkeys of feeding irradiated wheat flour and potato diet

The oral administration of 2,3-dihydroxybenzoic acid (DHB) to rats injected intravenously 1 hr previously with "2"3"9Pu citrate caused an increase in urinary excretion of Pu about 8 times that of animals treated with 0.9% NaCl (controls). Liver retention of Pu was decreased from 18% at 2 days in the control animals to 11% in DHB-treated rats. The skeletal retention was similarly reduced from 56% in the control group to 40% in the DHB-treated animals.

1977-05-01

248

Traumatic Brain Injury Generates Biphasic Hemodynamic ...

The effects on reproductive functions of feeding adult rhesus monkeys on a diet of irradiated wheat flour and potato was investigated. Wheat flour and potatoes were exposed to 75 000 and 10 000 rad, respectively, of #gamma#-irradiation and then fed to the animals. Various parameters of reproductive function were compared with those of animals fed on unirradiated food. These were: external changes in the reproductive organs, menstrual cycle, vaginal cytology, assay of urinary hormones (oestrogens and pregnanediol), and post-mortem histopathological examination of the reproductive organs. At the end of 3 months, the experimental and control animals behaved similarly with regard to their reproductive functions. (author).

249

Titration of diphtheria and tetanus antitoxins in sera of low titre

... animal through a mask by isoflurane and maintained by a balanced anesthesia, which consisted of an intramuscular injection of Innovar-vet (0.11 ...

1993-04-01

250

The role of contagious disease in udder health

Available methods for titrating diphtheria and tetanus antitoxin at low concentrations in human or animal blood are surveyed, with special attention to the amount of serum required for the test....Full Text Available

1971-01-01

251

The contribution of lower vertebrate animal models in human reproduction research

Contagious diseases are a threat to animal health and productivity, both nationally and at the farm level. This makes implementation of biosecurity measures to prevent their introduction and...Full Text Available

2009-10-01

252

British Library Electronic Table of Contents (United Kingdom)

Many advances have been carried out on the estrogens, GnRH and endocannabinoid system that have impact in the reproductive field. Indeed, estrogens, the generally accepted female hormones, have performed an unsuspected role in male sexual functions thanks to studies on non-mammalian vertebrates. Similarly, these animal models have provided important contributions to the identification of several GnRH ligand and receptor variants and their possible involvement in sexual behavior and gonadal function regulation. Moreover, the use of non-mammalian animal models has contributed to a better comprehension about the endocannabinoid system action in several mammalian reproductive events. We wish to highlight here how non-mammalian vertebrate animal model research contributes to advancements with i...

2011-01-01

253

The Natural Statistics of Audiovisual Speech

Humans, like other animals, are exposed to a continuous stream of signals, which are dynamic, multimodal, extended, and time varying in nature. This complex input space must be transduced and sampled...Full Text Available

2009-07-01

254

Tags ? NASA Astrobiology

Studies of the action of hypoglycin-a, a hypoglycaemic substance

Mar 15, 2010... Boulder have demonstrated that a five-nucleotide-long ribozyme can ... animals anoxia anoxia biomarker permian cambrian terrestrial ...

255

Snow Survey & Water Supply | NRCS

Some biological effects of hypoglycin-A, a compound isolated from the fruit of Blighia sapida, have been investigated. Administration of this compound to animals caused drowsiness...Full Text Available

1958-06-01

256

Simultaneous recognition and segmentation of cells: application in C.elegans

Programs & Services Technical Resources Land Use Soils Water Snow Survey & Water Supply Water Management Water Quality Watersheds Wetlands Air Plants & Animals Energy Climate...

2011-08-21

257

Role of spinal cyclooxygenase in human postoperative and chronic pain

Motivation: Automatic recognition of cell identities is critical for quantitative measurement, targeting and manipulation of cells of model animals at single-cell resolution. It has been...Full Text Available

2011-10-15

258

Reporting Problems to FDA

BackgroundNonsteroidal anti-inflammatory drugs are commonly used to treat postoperative and chronic pain. Animal studies suggest these drugs act in part by blocking...Full Text Available

2010-05-01

259

Medline Plus

Enter Search terms A-Z Index Home Food Drugs Medical Devices Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Radiation-Emitting Products Tobacco ...

260

Regulatory T cells in human disease and their potential for therapeutic manipulation

Proteomic strategies in multiple sclerosis and its animal models

Regulatory T cells are proposed to play a central role in the maintenance of immunological tolerance in the periphery, and studies in many animal models demonstrate their capacity to inhibit inflammatory...Full Text Available

2006-05-01

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261

Possible health effects of working with VDUs.

The early and precise diagnosis, the prognosis, and the clinical management of multiple sclerosis, remain a considerable challenge. In recent years, the development of novel and powerful proteomic...Full Text Available

2007-10-16

262

Polycarbonate Bottle Use and Urinary Bisphenol A Concentrations

A summary of the effects presented here is given in the table. The designation "factor present" implies that there is knowledge (from human or animal studies, or both) of a specific factor(s) present...Full Text Available

1989-04-01

263

Hypothalamic and dietary control of temperature-mediated longevity

BackgroundBisphenol A (BPA) is a high-production-volume chemical commonly used in the manufacture of polycarbonate plastic. Low-level concentrations of BPA in animals and possibly...Full Text Available

2009-09-01

264

Homocysteine and Familial Longevity: The Leiden Longevity Study

Temperature is an important modulator of longevity and aging in both poikilotherms and homeotherm animals. In homeotherms, temperature homeostasis is regulated primarily in the preoptic area...Full Text Available

2010-01-01

265

Handbook of Dangerous Animals for Field Personnel

Homocysteine concentrations are a read-out of methionine metabolism and have been related to changes in lifespan in animal models. In humans, high homocysteine concentrations are an important predictor...Full Text Available

266

Genomics of human longevity

... 110 Page 9. CONTENTS (Continued) Evaluation of Antivenin for Common Cobra (Naja naja) and Blue Krait (Bungarus caeruleus) Venoms I 13 ...

1972-12-01

267

Genomic view of the evolution of the complement system

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences...Full Text Available

2011-01-12

268

Food additives: an ethical evaluation.

The recent accumulation of genomic information of many representative animals has made it possible to trace the evolution of the complement system based on the presence or absence of each complement...Full Text Available

2006-09-01

269

Extreme resistance of bdelloid rotifers to ionizing radiation

Background Food additives are an integral part of the modern food system, but opinion polls showing most Europeans have worries about them imply an urgent need for ethical analysis of their use. Sources of data The existing literature on food ethics, safety assessment and animal testing. Areas of agreement Food additives provide certain advantages in terms of many people's lifestyles. Areas of controversy There are disagreements about the appropriate application of the precautionary principle and of the value and ethical validity of animal tests in assessing human safety. Growing points Most consumers have a poor understanding of the relative benefits and risks of additives, but concerns over food safety and animal testing remain high. Areas timely for developing research Examining the impacts of food additives on consumer sovereignty, consumer health and on animals used in safety testing should allow a ...

2011-07-01

270

Estimation of Human Toxicity From Animal Inhalation Toxicity ...

Rotifers of class Bdelloidea are common invertebrate animals with highly unusual characteristics, including apparently obligate asexuality, the ability to resume reproduction after desiccation at any...Full Text Available

2008-04-01

271

Estimation of Genetic Parameters for Growth-Related Traits in 9-month Old of Two Korean Abalone Subspecies, Haliotis discus hannai and H. discus discus, by Using Multiple Traits of Animal Model

... Bisgard, GE, Ruiz, AV, Grover, RF & Will, JA, "Ventilatory control in the ... Watkins, BE, Riegle, GD & Heisey, SR, "Respiratory responses to ACTH and ...

1997-10-01

272

Electromagnetic fields and public health.

Full Text Available

2009-12-01

273

Dishonest signalling in a fiddler crab.

A review of the literature is provided for the topic of health-related research and power frequency electromagnetic fields. Minimal evidence for concern is present on the basis of animal and plant research....Full Text Available

1987-11-01

274

Diagnostics of Radionuclides Effects Results

Animal communication theory predicts that low-frequency cheating should be common in generally honest signalling systems. However, perhaps because cheats are designed to go undetected, there are few...Full Text Available

2000-04-07

275

Developmentally programmed endoreduplication in animals

Development of New Methods and Means of Assessing of Consequences of Radionuclide and Heavy Metal Salt Effect, Criteria of Forecasting Physiological State and Productivity of the Farm Animals under Conditions of Ecological Pollution of Environment

276

Development of a microarray for identification of pathogenic Clostridium species

Development of a fertilized egg into an adult human requires trillions of cell divisions, the vast majority of which duplicate their genome once and only once. Nevertheless, trophoblast giant...Full Text Available

2009-05-15

277

Development of a New Generation of Small Scale Biomass ...

In recent years, Clostridium species have rapidly reemerged as human and animal pathogens. The detection and identification of pathogenic Clostridium species...Full Text Available

2010-02-01

278

Detection of genetic mutations in repetitive DNA sequences in somatic human cells after low-dose irradiation

... power from wood and bagasse as well as convert non-traditional fuel sources such as rice bulls, animal manure, cotton gin trash, straws, and ...

1995-08-01

279

Current Projects - Human Nutrition Research Center on Aging ...

... 3-89701-147-6 0949-2224 245 p. animal cells dna genetic radiation effects

1998-03-01

280

Cottonseed feeding delivers sufficient quantities of gossypol as a male deer contraceptive

diet and genetic obesity metabolic defects and inflammation. To determine the role of adipocyte death in promoting adipose tissue inflammation and insulin resistance in animal...

2011-08-31

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281

British Library Electronic Table of Contents (United Kingdom)

To define the quantitative and qualitative effects of gossypol (GP) on deer (Cervus elaphus) semen, the animals were fed cottonseed (CS). Adult stags each received 350?g of CS for 109?days. Animals received 15?mg of gossypol per kilogram body weight per day. Quantitative and qualitative parameters of experimental ejaculates (n?=?182) were compared to ejaculates (n?=?571) of control animals (n?=?5) collected during three previous natural reproductive seasons. Ejaculate fractions were evaluated by classical methods used in domestic animals. In this paper, we show that mature male deer fed CS exhibited morphological changes and decreased motility of spermatozoa and abnormalities in spermatogenesis. Radioimmunoassay measured concentrations of various steroid hormones (T-testosterone, A4-andros...

2008-01-01

282

Considerations on Temperature, Longevity and Aging

A modest reduction in body temperature prolongs longevity and possibly retards aging in both poikilotherm and homeotherm animals. Some of the possible mechanisms mediating these effects are...Full Text Available

2008-06-01

283

Biodiversity of Vibrios

Are animal models predictive for humans?

Vibrios are ubiquitous and abundant in the aquatic environment. A high abundance of vibrios is also detected in tissues and/or organs of various marine algae and animals, e.g., abalones, bivalves, corals,...Full Text Available

2004-09-01

284

Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain

It is one of the central aims of the philosophy of science to elucidate the meanings of scientific terms and also to think critically about their application. The focus of this essay is the scientific...Full Text Available

285

Animal Models for Radiation Injury, Protection and Therapy

The antinociceptive effects of honokiol and magnolol, two major bioactive constituents of the bark of Magnolia officinalis, were investigated on animal paw licking responses and thermal...Full Text Available

286

A search for the epidemic typhus agent in Ethiopian ticks*

... radiation during clinical therapy and exposures due to radiation accidents or attacks, in which the doses are uncontrolled ... only be used off-label in victims of radiation accidents or attacks. The idea...

287

[The contribution of N.I. Pirogov to the development of forensic medicine (on the occasion of his 200th birthday anniversary)].

The presence of antibodies to Rickettsia prowazeki in domestic animals from several parts of Africa, and the isolation of this rickettsia from the blood of goats and sheep and from...Full Text Available

1973-01-01

288

Triacontanol-mediated regulation of growth and other physiological attributes, active constituents and yield of Mentha arvensis L.

The main facets of professor N.I. Pirogov's professional activity are outlined. Forensic medicine (in the first place its organizational and practical aspects) was an integral component of his scientific and clinical work, along with applied anatomy and surgery. Landmark publications of N.I. Pirogov are listed with special reference to those concerned with forensic medical expertise of medical malpractice cases, postmortem inspection and intravital examination procedures, wound ballistics studies, the atlas of forensic pathology, etc. The surgeon and anatomist N.I. Pirogov can be justly regarded as a founder of forensic medicine in this country. PMID:21866839

289

British Library Electronic Table of Contents (United Kingdom)

Triacontanol (TRIA) has been realized as a potent plant growth promoting substance for a number of agricultural and horticultural crops. Out of a large number of essential oil bearing plants, mint (Mentha arvensis L.) constitutes the most important source of therapeutic agents used in the alternative systems of medicine. The mint plant has marvelous medicinal properties. In view of enhancing growth, yield and quality of this medicinally important plant, a pot experiment was conducted according to simple randomized block design. The experiment was aimed at studying the effect of four concentrations of TRIA (10?0, 10?7, 10?6 and 10?5?M) on the performance of mint with regard to growth and other physiological attributes, crop yield and quality attributes and the yield and contents of active c...

2011-01-01

290

Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine

CERN Document Server

This book examines the applications of Monte Carlo (MC) calculations in therapeutic nuclear medicine, from basic principles to computer implementations of software packages and their applications in radiation dosimetry and treatment planning. It is written for nuclear medicine physicists and physicians as well as radiation oncologists, and can serve as a supplementary text for medical imaging, radiation dosimetry and nuclear engineering graduate courses in science, medical and engineering faculties. With chapters is written by recognised authorities in that particular field, the book covers the entire range of MC applications in therapeutic medical and health physics, from its use in imaging prior to therapy to dose distribution modelling targeted radiotherapy. The contributions discuss the fundamental concepts of radiation dosimetry, radiobiological aspects of targeted radionuclide therapy and the various components and steps required for ...

2003-01-01

291

The usefulness of CBF brain SPECT in forensic medicine: the civil law codes cases. A description of four cases

The importance and unique aspects of radiation protection in medicine

The aim of this report was to assess the usefulness of cerebral blood flow (CBF) scanning utilising the SPECT technique in forensic medicine cases in the area of civil law cases. CBF SPECT scanning was performed in four patients utilising "9"9"mTc-ECD and a triple-head gammacamera. In the analysis both the asymmetry index and cerebellar normalisation were applied. Reference values were obtained by studying 30 healthy volunteers. In those cases CBF SPECT scanning played an important role in forensic argument. It influenced the sentence and the amount of financial compensation. CBF SPECT scanning may provide valuable information in forensic medicine argument in civil law cases, but only when taken together with psychometric tests and other neuroimaging methods (CT, MRI). The value of CBF SPECT scanning alone may be limited in judicial proceedings. (author)

292

British Library Electronic Table of Contents (United Kingdom)

Radiation protection in medicine has unique aspects and is an essential element of medical practice. Medical uses of radiation occur throughout the world, from large cities to rural clinics. It has been estimated that the number of medical procedures using radiation grew from about 1.7 billion in 1980 to almost 4 billion in 2007. In spite of these large numbers, there are many parts of the world without adequate equipment, where the ability to perform additional medical procedures would likely result in a net benefit. Medicine accounts for more than 99.9% of the per caput effective dose from man-made sources. The goal in medical exposure is not to give the lowest dose, but to provide the correct dose to enable the practitioner to make the diagnosis or cure a tumour. Too little or too much ...

2010-01-01

293

Studies on gamma irradiated medicinal plants and spices (1): Myristica argentea, Myristica fragrans, Coriandrum sativum and Foeniculum vulgare

Rapid ethnobotanical diagnosis of the Fulni-? Indigenous lands (NE Brazil): floristic survey and local conservation priorities for medicinal plants

Medicinal plants i.e. dried seeds of myristica argentea, myristica fragrans, coriandrum sativum and foeniculum vulgare were stored for 0 and 6 months, with and without gamma irradiation at 5 kGy. No detectable changes were seen in infrared and UV spectra, GLC chromatograms and refraction indices of steam distilled, essential oils from the irradiated medicinal plants. The same results were also obtained from irradiated samples stored for 6 months at ambient conditions. Storage for 6 months caused significant changes in the gas liquid chromatograms and UV spectra of all samples compared to non-stored samples. The moisture content of all samples packed in polyethylene bags seems to be constant after 6 months of storage. No measurable changes were found in the amount of essential oil content caused by irradiation.

1981-10-01

294

British Library Electronic Table of Contents (United Kingdom)

This study was developed as part of the project ?Studies for Environmental and Cultural Sustainability of the Fulni-? Medical System: Office on handling medicinal plants?. The Fulni-? people are located in Pernambuco State, Northeastern Brazil. One of the components of this project was an ethnobotanical diagnosis of the indigenous land, where a phytosociological survey was performed in an area of Caatinga vegetation, located at Ouricuri settlement. Based on these ethnobotanical data, we calculated a conservation priority index aiming to rank species that should receive immediate attention from the Fulni-? people. We identified 44 woody plants, 50% of which have a medicinal use. Among these, six plants were considered highly vulnerable and in need of immediate conservationist attention, in ...

2011-01-01

295

Estimation of essential and trace elements in some medicinal plants by PIXE and PIGE techniques

Determination of macro, micro nutrient and trace element concentrations in Indian medicinal and vegetable leaves using instrumental neutron activation analysis

Proton induced X-ray emission (PIXE) and proton induced {gamma}-ray emission (PIGE) techniques are employed for the determination of essential and trace elements in some commonly used medicinal plants of north east India. Light elements such as Na, Mg, Al and P are determined by PIGE while medium Z elements such as K, Ca, Mn, Fe, Cu, Zn, Rb and Sr are determined by PIXE. Analysis is performed on pellets (thick targets) prepared using powders of the specimens which, in turn, are obtained following a series of processing steps. Plant based biological certified reference materials (CRMs) served as standards for quantification. These elements are found to be present in varying concentrations in the studied plants, with the contents of Mn and Zn being notably large in certain specimens. Medicinal properties possessed by these plants have been correlated with their elemental distribution.

2008-04-15

296

Availability of essential trace elements in Ayurvedic Indian medicinal herbs using instrumental neutron activation analysis

Leafy samples often used as medicine in the Indian Ayurvedic system and vegetables were analyzed for 20 elements (As, Ba, Br, Ca, Ce, Cr, Cs, Co, Eu, Fe, K, La, Na, Rb, Sb, Sc, Sm, Sr, Th, Zn) by employing Instrumental Neutron Activation Analysis (INAA). The samples were irradiated at the 100 kW TRIGA-MAINZ nuclear reactor and the induced activities were counted by gamma ray spectrometry using an efficiency calibrated high resolution High Purity Germanium (HPGe) detector. The concentration of the elements in the medicinal and vegetable leaves and their biological effects on human beings are discussed.

1999-05-01

297

Withania somnifera Improves Semen Quality in Stress-Related Male Fertility

Specific parts of several plants (fruits, leaves, stem, bark and roots) often used as medicines in the Indian Ayurvedic system have been analysed for 20 elements (As, Ba, Br, Ca, Cl, Co, Cr, Cu, Fe, K, Mn, Mo, Na, P, Rb, Sb, Sc, Se, Sr and Zn) by employing instrumental neutron activation analysis (INAA). The samples were irradiated with thermal neutrons in a nuclear reactor and the induced activity was counted using high resolution gamma ray spectrometry. Most of the medicinal herbs have been found to be rich in one or more of the elements under study. (Author).

1997-01-01

298

Towards Commercial Production of Sponge Medicines

Stress has been reported to be a causative factor for male infertility. Withania somnifera has been documented in Ayurveda and Unani medicine system for its stress-combating properties....Full Text Available

2011-01-01

299

Therapeutic potential of RNA interference in pain medicine

Sponges can provide potential drugs against many major world-wide occurring diseases. Despite the high potential of sponge derived drugs no sustainable production method has been developed. Thus far...Full Text Available

300

The Chinese Nail Murders: forensic medicine in Imperial China.

In recent years RNA interference (RNAi) has rapidly become the most widely used tool for gene knockdown due to its high specificity and potency. RNAi is an evolutionarily conserved mechanism...Full Text Available

2009-01-01

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301

The 4th Annual International Conference on Hormesis: Implications for Toxicology, Medicine and Risk Assessment. The annual Meeting of the International Hormesis Society. Abstract Book. June 6-8, 2005, University of Massachusetts, Amherst, MA. 26 pages.

Robert van Gulik was a respected Dutch sinologist and author who first translated a collection of traditional Chinese detective stories into English and then created additional fictional stories based...Full Text Available

1999-11-01

302

No abstract prepared.

2007-01-01

303

SNQ for medical research

Rubella screening and vaccination program for US Air Force trainees: an analysis of findings.

The planned spallation source can be of considerable significance for biomedical basic research and for clinically relevant diagnostic and therapeutic applications. The following gives a brief description and explanations for its possible use in clinical medicine: I. Treatment of Malignant Tumors II. Production of Isotopes for Biochemical Investigations in Living Organisms for Diagnostic Purposes.

1984-12-01

304

Review of Evidence Suggesting That the Fascia Network Could Be the Anatomical Basis for Acupoints and Meridians in the Human Body

A preventive medicine program of rubella control for trainees at the Air Force Military Training Center, Lackland AFB, Texas, was begun in October 1977. Incoming trainees were screened for rubella susceptibility,...Full Text Available

1982-03-01

305

Radiation risks for medical applications

The anatomical basis for the concept of meridians in traditional Chinese medicine (TCM) has not been resolved. This paper reviews the evidence supporting a relationship between acupuncture points/meridians...Full Text Available

2011-01-01

306

Quality assessment of reporting of randomization, allocation concealment, and blinding in traditional chinese medicine RCTs: A review of 3159 RCTs identified from 260 systematic reviews

The achievements made in the field of radiation protection over the past 20 years are outlined. Risk analysis as applied to medicine is considered and genetic significant doses, genetic risks, somatic effective doses and somatic risks are discussed. (C.F.).

1980-05-31

307

Protective effects of hydroalcoholic extract from rhizomes of Cynodon dactylon (L.) Pers. on compensated right heart failure in rats

BackgroundRandomized controlled trials (RCTs) which are of poor quality tend to exaggerate the effect estimate and lead to wrong or misleading conclusions. The aim of this study...Full Text Available

308

Prematurity as a public health problem: US policy from the 1920s to the 1960s.

BackgroundThe rhizomes of Cynodon dactylon are used for the treatment of heart failure in folk medicine. In the present study, we investigated the effects of hydroalcoholic...Full Text Available

309

Perceived Functioning Has Ethnic-specific Associations in Systemic Sclerosis: Another Dimension of Personalized Medicine

During the 1920s and 1930s, a number of physicians created model premature infant stations in select hospitals, arguing that medicine could successfully treat premature infants, most of whom could be...Full Text Available

1996-06-01

310

Male Germ Cell Apoptosis and Epigenetic Histone Modification Induced by Tripterygium wilfordii Hook F

ObjectiveTo measure self-reported physical and mental functioning and associated clinical features at study entry in 3 ethnic groups with systemic sclerosis (SSc).Full Text Available

2009-12-01

311

Multiglycosides of Tripterygium wilfordii Hook f (GTW), a Chinese herb-derived medicine used as a remedy for rheumatoid arthritis, are considered to be a reversible anti-fertility drug...Full Text Available

312

Learn CPR You Can Do It!

Kaposi's sarcoma involving the thyroid in a patient with AIDS

Have a question about CPR? Click Here To Ask The Doctor Learn CPR is a free public service supported by the University of Washington School of Medicine . Learn the basics of CPR - cardiopulmonary resuscitation. The American Heart Association issued updated ...

313

Integrated Advanced Information Management Systems: a twenty-year history at the University of Cincinnati*

A 30-year-old man with acquired immune deficiency syndrome (AIDS) and Kaposi's sarcoma had a palpable thyroid mass and cervical lymphadenopathy. Nuclear medicine and ultrasound scans revealed multiple thyroid nodules. Results of biopsy showed Kaposi's sarcoma metastatic to the thyroid.

314

Hepatoprotective Effects of Orthosiphon stamineus Extract on Thioacetamide-Induced Liver Cirrhosis in Rats

The University of Cincinnati (UC) has been active in the National Library of Medicine's Integrated Advanced Information Management Systems (IAIMS) program since IAIMS' inception in 1984. UC received...Full Text Available

2004-04-01

315

Heart Rate Characteristics: Physiomarkers for Detection of Late-Onset Neonatal Sepsis

Orthosiphon stamineus as medicinal plant is commonly used in Malaysia for treatment of hepatitis and jaundice; in this study, the ethanol extracts were applied to evaluate the...Full Text Available

2011-01-01

316

Gonorrhoea in men: clinical and diagnostic aspects.

SynopsisEarly detection of late onset neonatal sepsis, prior to obvious and potentially catastrophic clinical signs, is an important goal in neonatal medicine. Sepsis causes a...Full Text Available

2010-09-01

317

Genetic screening: The vista of genomic medicine

AIM: To review the features of gonococcal infection in men in the 1990s. METHODS: A retrospective study of all men with gonorrhoea presenting to an inner city department of genitourinary medicine in...Full Text Available

1996-12-01

318

Genetic Evidence for Inhibition of Bacterial Division Protein FtsZ by Berberine

The accelerating development of biochemical and DNA-based diagnostic tests for human genetic conditions in the last decade has engendered a revolution in genetic diagnosis. Both genetic testing and...Full Text Available

2011-01-01

319

Gamuts in nuclear medicine

BackgroundBerberine is a plant alkaloid that is widely used as an anti-infective in traditional medicine. Escherichia coli exposed to berberine form filaments, suggesting...Full Text Available

320

Functional Analysis of Neurovascular Adaptations to Exercise in the Dentate Gyrus of Young Adult Mice Associated With Cognitive Gain

This book provides differential diagnostic possibilities of specific scan abnormalities in one volume for easy reference. This book is organized by organ systems and covers the central nervous system, the endocrine, skeletal, pulmonary, gastrointestinal, genitourinary, and cardiovascular systems. The gamuts are designed to teach differential diagnosis and to assist in the actual interpretation of patient slides.

1983-01-01

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321

Evaluation of fungal burden of medicinal plants submitted to gamma radiation process after 30 days

The discovery that aerobic exercise increases adult hippocampal neurogenesis and can enhance cognitive performance holds promise as a model for regenerative medicine. This study adds two new...Full Text Available

2009-10-01

322

Ethnopharmacological evaluation of radal (leaves of Lomatia hirsuta) and isolation of 2-methoxyjuglone

Forty samples of medicinal plants (Peumus boldus, Camellia sinensis, Maytenus ilicifolia and Cassia angustifolia), purchased from pharmacies and street market in the five cities of Sao Paulo State, were irradiated using a "6"0Co gamma ray source (Gammacell) with a dose of 10.0 kGy, delivered at dose rate of 3.0 kGy/h. Nonirradiated samples were used as controls of fungal isolates. For fungal counts and identification in medicinal plants a serial dilutions from 10"-"1 to 10"-"6 of the samples were seeded in duplicates and plated using the method in Dichloran 18% Glycerol Agar (DG 18) and were counted after five days at 25 deg C. Mycological analysis of control samples revealed the presence of genera Aspergillus and Penicillium, which are known as toxigenic fungi. The process of gamma radiation was effective in reducing the number of colony forming units (cfu/g) in all irradiated samples of medicinal plants after 30 days, ...

323

Ethnobotanical notes about some uses of medicinal plants in Alto Tirreno Cosentino area (Calabria, Southern Italy)

BackgroundLeaves of Lomatia hirsuta are used in traditional medicine in Chile under the common name of "radal". A tea of radal is traditionally used for treatment...Full Text Available

324

Estimation of trace elements in some anti-diabetic medicinal plants using PIXE technique

BackgroundThe present paper contributes to enrich the ethnobotanical knowledge of Calabria region (Southern Italy). Research was carried out in Alto Tirreno Cosentino, a small area...Full Text Available

325

Endobronchial Stent Insertion to Manage Hemoptysis caused by Lung Cancer

Trace elemental analysis was carried out in various parts of some anti-diabetic medicinal plants using PIXE technique. A 3 MeV proton beam was used to excite the samples. The elements Cl, K, Ca, Ti, Cr, Mn, Fe, Ni, Cu, Zn, Br, Rb and Sr were identified and their concentrations were estimated. The results of the present study provide justification for the usage of these medicinal plants in the treatment of diabetes mellitus (DM) since they are found to contain appreciable amounts of the elements K, Ca, Cr, Mn, Cu, and Zn, which are responsible for potentiating insulin action. Our results show that the analyzed medicinal plants can be considered as potential sources for providing a reasonable amount of the required elements other than diet to the patients of DM. Moreover, these results can be used to set new standards for prescribing the dosage of the herbal drugs prepared from these plant materials.

2006-08-15

326

Efficacy and safety of Ayurvedic medicines: Recommending equivalence trial design and proposing safety index

Hemoptysis in patients with lung cancer is not uncommon and sometimes have dangerous consequences. Hemoptysis has been managed with various treatment options other than surgery and medicine, such as...Full Text Available

2010-08-01

327

Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus

Ayurvedic drugs have begun to be evaluated in controlled clinical trials. The trials, often placebo controlled, are usually designed to demonstrate superiority. Though the results have been usually...Full Text Available

2010-07-01

328

Effect of gamma radiation on the survival of fungal and actinomycetal florae contaminating medicinal plants

One-third of botanical remedies from southern Italy are used to treat skin and soft tissue infection (SSTI). Staphylococcus aureus, a common cause of SSTI, has generated increasing...Full Text Available

2008-08-13

329

Doppler imaging using spectrally-encoded endoscopy

This study evaluates the effect of gamma radiation on the viability of fungi and actinomycetes that contaminate medicinal plants. The relationship between the total lipids of some fungi and actinomycetes and their sensitivity to gamma radiation is also investigated. The data reveal that the viable counts of these florae decrease approximately exponentially with the radiation dose, the effective dose for the elimination of these microorganisms being about 5 kGy for all the medicinal plants under study. Response of pure cultures of fungi and actinomycetes isolated from medicinal plants to increasing absorbed doses of gamma radiation indicate that an increase in radioresistance is in the following order: Streptomyces rimosus, Fusarium solani, Nocardia kuroishii. F. oxysporum, A. fumigatus, A. flavus, A. parasiticus and A. ochraceus. The total lipid contents of molds and actinomycetes have been reported to be increased by ...

1997-01-01

330

Diagnosis of Ewing's sarcoma in the thoracic spine - problems in differential diagnosis

The capability to image tissue motion such as blood flow through an endoscope could have many applications in medicine. Spectrally encoded endoscopy (SEE) is a recently introduced technique...Full Text Available

2008-09-15

331

Determination of metals in medicinal plants destined to phytotherapic products by X-ray fluorescence with synchrotron radiation (SYXRF); Determinacao de metais em plantas medicinais destinadas a producao de fitoterapicos por fluorescencia de raios-X com luz sincrotron (SYXRF)

Spinal Ewing's sarcomas are rare and cause problems in differential diagnosis. The radiologic, nuclear medicine and CT findings in two children with histologically proven Ewing's sarcoma are presented and problems in differential diagnosis discussed. Biopsy should be done early. (orig.).

332

Determination of Organ Doses During Radiological Examinations and Calculation of Somatically Significant Dose.

No abstract prepared.

2003-07-01

333

Cytoprotective Activity of Glycyrrhizae radix Extract Against Arsenite-induced Cytotoxicity

Examples are used to demonstrate that a shift in the point of emphasis is necessary with regard to radiation hazard in medicinal X-ray diagnosis. The parameters employed in this study to calculate somatic dose (SD) and somatically significant dose (SSD) m...

1980-01-01

334

Complement-fixing Activity of Fulvic Acid from Shilajit and Other Natural Sources

Licorice, Glycyrrhizae radix, is one of the herbal medicines in East Asia that has been commonly used for treating various diseases, including stomach disorders. This study investigated...Full Text Available

2008-06-01

335

Comparative Medicine - National Center for Research Resources...

Shilajit has been used traditionally in folk medicine for treatment of a variety of disorders, including syndromes involving excessive complement activation. Extracts of Shilajit contain significant...Full Text Available

2009-03-01

336

Circadian Rhythm Sleep Disorders: Part I, Basic Principles, Shift Work and Jet Lag DisordersAn American Academy of Sleep Medicine Review

and Antibody Responses of Rhesus Macaques Exposed to the Human Gammaretrovirus XMRV external link, opens in new window J Virol. 2011 May;85(9):4547-57 Detection of CWD...

2011-10-15

337

Application of rhenium-188 HEDP in bone metastases therapy

Objective:This the first of two articles reviewing the scientific literature on the evaluation and treatment of circadian rhythm sleep disorders (CRSDs), employing the methodology...Full Text Available

2007-11-01

338

Antipyretic and antibacterial activity of Chloranthus erectus (Buch.-Ham.) Verdcourt leaf extract: A popular folk medicine of Arunachal Pradesh

Radionuclide bone metastases therapy is a major achievement of nuclear medicine. Development of less radiotoxic and more effective radiopharmaceuticals is therefore a challenge for radiopharmacists and industry. This paper reviews the application of rhenium-188 HEDP as a reactor- or generator-produced nuclide for bone metastases therapy. (author)

339

Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-?B-dependent iNOS and proinflammatory cytokines production

Objective:The main objective of this work was to study the antipyretic and antibacterial activity of C. erectus (Buch.-Ham.) Verdcourt leaf extract in an...Full Text Available

2010-10-01

340

Anti-Inflammatory and Immunomodulatory Effects of Paeonia Lactiflora Pall., a Traditional Chinese Herbal Medicine

Background and purpose:Glycyrrhizae radix has been widely used as a cytoprotective, plant-derived medicine. We have identified a flavanoid, liquiritigenin, as an...Full Text Available

2008-05-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

341

Acute liver injury associated with the use of herbal preparations containing glucosamine: three case studies

In China, Korea, and Japan, a decoction of the dried root without bark of Paeonia lactiflora Pall. has been used in the treatment of rheumatoid arthritis, systemic lupus erythematosus,...Full Text Available

342

Abrogation of E-Cadherin-Mediated Cellular Aggregation Allows Proliferation of Pluripotent Mouse Embryonic Stem Cells in Shake Flask Bioreactors

The use of complementary and alternative medicines is becoming increasingly popular in Western society. As a result the number of reported adverse reactions is increasing. Glucosamine is a herbal remedy...Full Text Available

343

AEROSPACE MEDICINE AND BIOLOGY - NASA Technical Reports Server

BackgroundA fundamental requirement for the exploitation of embryonic stem (ES) cells in regenerative medicine is the ability to reproducibly derive sufficient numbers of cells of...Full Text Available

344

A polyacetylene compound from herbal medicine regulates genes associated with thrombosis in endothelial cells

Learning curve models have gained widespread acceptance as a technique for analyzing and ...... flight segment in F4 pilots p 163 A91-30966. WILSON, JOHN W . ...

345

A Novel Information Retrieval Model for High-Throughput Molecular Medicine Modalities

From Toki-shakuyaku-san, an herbal formulation for “cleansing stagnated blood,” a key gene regulatory compound was purified and identified through a screening based on DNA microarray...Full Text Available

2007-12-15

346

The pharmacological activity of medical herbs after microbiological decontamination by irradiation

Significant research has been devoted to predicting diagnosis, prognosis, and response to treatment using high-throughput assays. Rapid translation into clinical results hinges upon efficient access...Full Text Available

347

The effects of packaging materials on microbe population in irradiated traditional herbal medicines

In the Institute of Nuclear Chemistry and Technology research on microbiological decontamination of medicinal herbs by irradiation has been carried out since 1996. It was shown that using ionizing radiation (a dose of 10 kGy) can obtain satisfactory results of microbiological decontamination of these products. The content of essential biologically active substances such as essential oils, flavonoids, glycosides, anthocyans, antra-compounds, poliphenoloacids, triterpene saponins, oleanosides and plants mucus did not change significantly after irradiation. Pharmacological activity of medicinal herbs has been found satisfactory after microbiological decontamination by irradiation.

2000-03-01

348

Role of nuclear medicine bone scans in evaluating pain in athletic injuries

Microbial population and moisture content of traditional herbal medicines contaminated with 3 kinds of aerobic microbes, packed in 5 kinds of plastic packaging materials, followed by irradiation at minimum dose of 5 kGy and stored for 6 months were investigated. The highest reduction of microbial counts during storage was observed on samples packed in polyethylene bags. All of packaging materials used were found to be impermeable to microbes and water vapour. Radiation and packaging materials used acted synergistically to inactivate microbes durind storage. The microbial counts decreased as much as 2 to 4 log cycles during storage. (author).

349

Radioprotective activity in some medicinal herbs

The utilization of nuclear medicine bone scanning examinations early in the diagnostic process allows physicians to render prompt and correct treatment in urgent or difficult athletic cases. Bone scanning should be performed for athletic injuries whenever (1) x-rays are normal but bone or joint pain persists; (2) x-rays are positive but it cannot be determined if the findings are acute or chronic; (3) soft-tissue injuries present and x-rays are not useful; and (4) bone pain or joint impairment present without a history of trauma.89 references.

1987-10-01

350

Probable role of trace elements of some medicinal plants in cardio-vascular diseases

Water-soluble, ethanol-insoluble extracts prepared from several medicinal herbs of the Araliaceae and other families were tested for their radioprotective activity by either measuring 30 days survival rates (a commonly applied method) or counting the thrombocytes 14 days after irradiation (an improved method) in mice. The extracts were i.p. injected once within 4 min after the whole body X-ray irradiation. Of 12 materials examined, Aralia elata, Angelica acutiloba and Morus bombysis seemed to be good starting materials for preparing radioprotective substance(s) because of their relatively high specific activity and high yields of the extracts. (author).

1993-09-01

351

Determination of constituent elements in some Nigerian medicinal plants by thermal-neutron activation analysis

A number of herbal drugs are used in the Unani (Greco-Arab) System of Medicine for cardiovascular diseases. The herbs were analyzed by flame AAS and ICP-AES to determine if their therapeutic actions can be associated with the elements present in them. Cadmium, cobalt, chromium, copper, iron, potassium, magnesium, manganese, sodium, nickel, phosphorus, lead and zinc were some of the elements which play various roles in cardiovascular affections. An effort was made to correlate the role of these elements in cardiac diseases. (Auth.). 2 tabs., 32 refs.

352

Urban epizootic of rabies in Mexico: epidemiology and impact of animal bite injuries.

This study of the inorganic chemical composition of 10 different Nigerian medicinal plant species, using the technique of instrumental neutron activation analysis (INAA), resulted in the determination of the concentrations of 18 major, minor, and trace elements: Al, Ba, Br, Ca, Cl, Eu, Fe, Ga, K, La, Mn, Na, Sb, Sc, Si, Sm, V, and Zn. The parts of the plants used were roots, leaves, and bark. The NBS SRM 1571 Orchard Leaves was also analyzed to assess the accuracy of the procedures used. 21 refs., 4 tables.

1984-04-02

353

Transfer of Plasmid-Mediated CTX-M-9 from Salmonella enterica Serotype Virchow to Enterobacteriaceae in Human Flora-Associated Rats Treated with Cefixime?

From 1 July 1987 to 31 December 1988, a total of 317 animals (91% of which were dogs) were confirmed to have rabies in Hermosillo, Mexico. The median age of rabid dogs was 1 year, 69% were male, and...Full Text Available

1993-01-01

354

Modalidade de morte em mamiferos expostos a irradiacao de corpo inteiro (sindrome aguda da radiacao). (Modes of death in mammals exposed to whole body radiation (acute radiation syndromes)).

Food animals are a potential source of CTX-M resistance genes for humans. We evaluated the transfer of the bla_CTX-M-9 gene from an animal strain of Salmonella enterica...Full Text Available

2010-01-01

355

Failure of desferrioxamine to modify the toxicity of paraquat in rats

When an animal is exposed to a sufficient amount of radiation, there will be changes in many organs of the body, and as a result of either the effects in one particular organ or the interaction of effects in several organs, the animal as a whole will show...

1990-01-01

356

Extended-Spectrum-?-Lactamase-Producing Escherichia coli Strains Isolated from Farm Animals from 1999 to 2002: Report from the Japanese Veterinary Antimicrobial Resistance Monitoring Program

The feasibility of using desferrioxamine (DF), an iron chelator, as a therapeutic agent against paraquat (PQ/sup + +/) toxicity in male Sprague-Dawley rats was explored, based on the rationale of limiting toxic hydroxyl radical production from hydrogen peroxide by removing redox-active iron. Body weights, mortality, and lung histopathology were followed for periods up to 14 days after intraperitoneal injection of PQ/sup + +/ (20 or 25 mg/kg body weight) with or without concurrent daily subcutaneous injections of DF (300 mg/day). Animals receiving PQ/sup + +/ showed the expected typical patterns of mortality and of lung histopathology, namely: marked edema, subpleural hemorrhage, acute inflammation, perivascular mononuclear cell infiltrates, sloughing of alveolar and bronchiolar lining cells, and diffuse interstitial fibrosis. Desferrioxamine alone was non-toxic. Surprisingly, results when both PQ/sup + +/ and DF were administered indicated a failure of DF to ...

1985-01-01

357

Biological parameters of transgenic rabbits

A nationwide surveillance for antimicrobial susceptibility in Escherichia coli strains isolated from food-producing animals in Japan was conducted from 1999 to 2002. Eighteen cefazolin-resistant...Full Text Available

2005-08-01

358

British Library Electronic Table of Contents (United Kingdom)

The investigations were conducted at the Center of Biotechnology and Molecular Diagnostics of the All-Russian Animal Husbandry Research Institute, where a number of valuable transgenic animals (rabbits, sheep, and pigs) have been produced over the course of 20 years. The article presents the blood indices of control and transgenic rabbits with an integrated insulin gene.

2011-01-01

359

An investigation of some Turkish herbal medicines in Salmonella typhimurium and in the COMET assay in human lymphocytes.

Development of a methodology to assess organometallic effects on bioenergetic systems

Medicinal plants play a major role in the life of Turkish people and of late medicinal plant usage has increased in many countries. Green plants in general contain mutagenic and carcinogenic substances, but there is little information about the biological activities of herbal medicine. In the present study, therefore, various Turkish medicinal herbs were investigated for their genotoxic potential in the Salmonella typhimurium microsomal activation assay and the alkaline single cell gel electrophoresis (COMET) assay. Extracts from these medicinal herbs and some fractions of these extracts were examined. The species investigated were Arctium minus, Ecballium elatterium, Momordica charantia, Plantago major, Urtica dioica, Viscum album, Salvia triloba, Euphorbia rigida, Stachys lavandulifolia, Acteoside, Abies nordmannia. They are used for various immune disorders and are applied either ...

1996-01-01

360

Scale-up of Multidrug-Resistant Tuberculosis Laboratory Services, Peru

A methodology for assessing the impact of subacute concentrations of organometallic agents on bioenergetic and oxidative damage processes in animals, cells and energy transducing subcellular organelles is being developed. Several of the assays are noninvasive and thus lend themselves to human tests. At the whole-animal level we utilize a treadmill chamber where physiological parameters of exercising animals are monitored. These include parameters of whole animals' work performance such as oxygen consumption, carbon dioxide evolution and endurance. Oxidative damage can be monitored in experiments by analyzing expired air of the animals for ethane and n-pentane. These alkanes correlate with lipid peroxidation in vivo. At the cellular and subcellular levels, respiratory activity, lipid peroxidation and free radical species are assayed. Respiratory activity is measured in ...

1981-06-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

361

Coryneform bacteria in infectious diseases: clinical and laboratory aspects.

Over the past 10 years, the Peruvian National Tuberculosis (TB) Program, the National Reference Laboratory (NRL), Socios en Salud, and US partners have worked to strengthen the national TB laboratory...Full Text Available

2008-05-01

362

A conceptual model for laboratory ventilation greenhouse gas planning

Coryneform isolates from clinical specimens frequently cannot be identified by either reference laboratories or research laboratories. Many of these organisms are skin flora that belong to a large number...Full Text Available

1990-07-01

363

British Library Electronic Table of Contents (United Kingdom)

There is increasing pressure to operate laboratory facilities in environmentally and financially sustainable ways. A key factor in achieving this goal is careful consideration of how energy is used by the buildings' ventilation system, both for conditioning air supplied to the laboratories and the energy used moving air through the building. Traditionally, laboratory energy use is treated as an engineering concern within the scope of the building's overall design and operation. However, this approach limits the involvement of key stakeholders in many important decisions and can lead to unexpected safety concerns for the laboratory's users. We believe that a broad view of the parties affected by a laboratory building's operations is necessary to avoid having the various stakeholders working...

2011-01-01

364

Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum

Today in History: December 17

BackgroundDuplications of stretches of the genome are an important source of individual genetic variation, but their unrecognized presence in laboratory organisms would be a confounding...Full Text Available

2008-01-01

365

The Laboratory for Research on the Structure of Matter (LRSM...

as manufacturing plants and laboratories, including the Chemical Laboratory at the House of David in Benton Harbor, Michigan. Built in America: Historic Building Buildings Survey/...

2010-12-17

366

Statement of work for analytical services provided by PNNL`sanalytical chemistry laboratory

as one of the first Materials Research Laboratories to be funded by the forerunner of DARPA. In 1972 funding was taken over by the National Science Foundation's Division of...

2011-08-18

367

Savannah River Laboratory monthly report, November 1991

The purpose of this statement of work (SOW) is to establish laboratory analytical criteria and requirements for radioactive airborne emissions measurement sample and/or analysis activities.

1997-06-30

368

Savannah River Laboratory monthly report, November 1991

This document details monthly activities at the Savannah River Laboratory. Topics addressed are reactor operation; tritium facilities and production; separation operations; environmental concerns; and waste management. (FI)

1991-01-01

369

Pigment Analysis by HPLC at Horn Point Laboratory

This document details monthly activities at the Savannah River Laboratory. Topics addressed are reactor operation; tritium facilities and production; separation operations; environmental concerns; and waste management. (FI)

1991-12-31

370

Funding will push battery technology from Argonne Laboratory

Oct 30, 2006 ... Pigment Analysis by HPLC at Horn Point Laboratory. Laurie Van Heukelem. Crystal Thomas. Meg Maddox. University of Maryland Center for ...

371

Interconnected project 'Development and testing of a biological monitoring for effects of polycyclic aromatic hydrocarbons on man'

Publications Science Highlights Researcher Profiles Internship Funding to push battery technology from Argonne Laboratory to marketplace Bookmark and Share (Download...

2011-08-27

372

Influence of weather on the behaviour of outdoor-wintered beef cattle in Scandinavia

The research project had the aim to develop a standard for measuring individual, inner stresses from polycyclic aromatic hydrocarbons (PAHs) at work. The employed method was by characterizing PAHs and metabolites of PAHs to be identified in urine with a view to developing a biological monitoring of professionally exposured persons. Using a number of PAHs relevant to work, the following questions were studied in cell culture systems and different animal-experimental models: Which metabolites are formed from the PAHs used in cell culture systems and the different animal-experimental models, and what are their ratios in percent? What percentage of a PAH is excreted by experimental animals in their urine and faeces on the first, second, and third day following different forms of application? What is the scale of the individual range of variation of PAH mass excretion? Are these results transferable to man? (orig.).

1992-01-01

373

British Library Electronic Table of Contents (United Kingdom)

The aim of the present investigation was to study the effect of weather and available protection on the behaviour of outdoor-wintered beef cattle (Bos taurus). A herd of 78-85 cattle head was studied during four winter months in the Southwest of Sweden. Protection was offered by coniferous forest situated on and around the 12ha pasture, which we divided into protection categories. During 240h we observed 10 cows and 10 heifers as focal animals (each 3h/month) during day time and adjusted observation times to the altitude of the sun. Close to the animals and at an unprotected spot of the pasture we measured temperature, wind speed and solar radiation and combined these variables to a single measure called Wind Chill Temperature (WCT). During observations the animals were in the forest in 12...

2011-01-01

374

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters

British Library Electronic Table of Contents (United Kingdom)

Research on hematological disorders relies on suitable animal models. We retrospectively evaluated the use of the hematological parameters hematocrit (HCT), hemoglobin (HGB), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), red blood cell count (RBC), white blood cell count (WBC), and platelet count (PLT) in the phenotype-driven Munich N-ethyl-N-nitrosourea (ENU) mouse mutagenesis project as parameters for the generation of novel animal models for human diseases. The analysis was carried out on more than 16,000 G1 and G3 offspring of chemically mutagenized inbred C3H mice to detect dominant and recessive mutations leading to deviations in the levels of the chosen parameters. Identification of animals exhibiting altered valu...

2011-01-01

375

Exploration of the hypothalamic?pituitary?adrenal function as a tool to evaluate animal welfare

British Library Electronic Table of Contents (United Kingdom)

Measuring HPA axis activity is the standard approach to the study of stress and welfare in farm animals. Although the reference technique is the use of blood plasma to measure glucocorticoid hormones (cortisol or corticosterone), several alternative methods such as the measurement of corticosteroids in saliva, urine or faeces have been developed to overcome the stress induced by blood sampling itself. In chronic stress situations, as is frequently the case in studies about farm animal welfare, hormonal secretions are usually unchanged but dynamic testing allows the demonstration of functional changes at several levels of the system, including the sensitization of the adrenal cortex to ACTH and the resistance of the axis to feedback inhibition by corticosteroids (dexamethasone suppression t...

2007-01-01

376

Experimental bovine trypanosomiasis. Changes in serum immunoglobulins, complement and complement components in infected animals.

Effects of swimming training at the intensity equivalent to aerobic/anaerobic metabolic transition in alloxan diabetic rats

In three calves experimentally infected with Trypanosoma congolense the amounts of IgG1 and IgG2 were little changed and similar to those of normal animals. IgM increased in amount early in the infection and the amount of the increase appeared related to the parasite burden. The amounts of IgA and IgE were both much decreased and this also appeared related to the numbers of parasites in the blood. There was a decrease in the amounts of total haemolytic complement and complement components C1, C1q and C3 in the infected calves. Furthermore the amounts of properdin fluctuated with the cyclical changes in numbers of T. congolense parasites in the individual calves. No significant change in the amount of C8 was observed. It is considered that activation of both the alternative and the classical complement pathways occurs in trypanosome infected animals but that neither pathway goes to its terminal stages.

1978-11-01

377

British Library Electronic Table of Contents (United Kingdom)

The present study was designed to determine the exercise intensity equivalent to the metabolic aerobic/anaerobic transition of alloxan diabetic rats, through lactate minimum test (LMT), and to evaluate the effects of swimming exercise at this intensity (LM) on the glucose and protein metabolism of these animals. Adult male Wistar rats received alloxan (SD, alloxan-injected rats that remained sedentary) intravenously (30 mg kg?1 body weight) for diabetes induction. As controls (SC, vehicle-injected rats that remained sedentary), vehicle-injected rats were utilized. Two weeks later, the animals were submitted to oral glucose tolerance test (oGTT) and LMT. After the tests, some of the animals were submitted to swimming exercise training [TC (vehicle-injected rats that performed a 6-week exerc...

2007-01-01

378

Effects of burrow condition and seed handling time on hoarding strategies of Edward's long-tailed rat (Leopoldamys edwardsi)

British Library Electronic Table of Contents (United Kingdom)

Many hoarding rodents use burrows not only for dwelling and protection from natural enemies, but also for food storage. However, little is known how burrows used by scatter-hoarding animals influence their foraging behaviors. In addition, handling time for a given food item has a fundamental impact on hoarding strategies of these hoarding animals: food items with longer handling time are more likely to be hoarded due to increasing predation risk because the animals spend more time outside their burrows if they consumed such food. By providing with two types of artificial burrows (aboveground vs. underground) and two types of food items (i.e. seeds) with contrasting handling times, we investigated how burrow condition and handling time co-influence hoarding strategies of a key scatter-hoard...

2010-01-01

379

The phenomenon of microscale flow and mass transfer in medicinal herb materials

Evaluation of fungal bio burden and mycotoxins presence in irradiated samples of medicinal plants purchased from wholesale and retail market

Microwave assisted extraction (MAE) is a combination of a microwave technique and conventional solvent extraction used in the modernization of traditional Chinese medicine. The effective component of medicinal herbs is mostly cellular material which can be released via solvent extraction. The material is diffused to solvents via the porous membrane wall. The structure of herb morphology and characteristics of the solute's molecular weight play an important role in the extraction process of target compounds. Astragalus pieces were chosen for this study in which an ultra-filtration membrane method was used to determine the molecular weight distribution characteristics of Astragalus water extraction liquid in the process of MAE. The fine structure of matrix materials was also characterized by scanning election microscopy (SEM). The phenomenon of mass flow and mass transfer in the plant porous media was discussed along with the enhancement ...

2008-07-01

380

Volatilization of fluorides from solid uranium(IV)fluoride

This present study evaluated the effect of gamma radiation on the fungal survival in packed medicinal plants, purchased from wholesale and retail market, in different period (0 and 30 days) after the treatment. Five kind of medicinal plants (Peumus boldus, Camellia sinensis, Maytenus ilicifolia, Paullinia cupana and Cassia angustifolia), were collected from different cities of Sao Paulo State, and submitted to irradiation treatment using a 60Co source (type Gammacell 220) with doses of 5,0 kGy and 10 kGy and at dose rate of 3.0 kGy/h. Non-irradiated samples (control group) were used for fungal counts and serial dilutions from 10-1 to 10-6 of the samples were seeded in duplicates and plated using the surface culture method in Dichloran 18% Glycerol Agar (DG 18) and were counted after five days at 25 deg C. The control group revealed the presence of genera Aspergillus and Penicillium, which are known as toxigenic fungi and a few samples of ...

2006-12-20

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

381

Role of congenital rubella reference laboratory: 21-months-surveillance in Liguria, Italy.

... deposition evaporation fission products fluorides iodine 134 laboratory

1971-02-01

382

Mobile laboratory for controlling and monitoring atmospheric pollution

PMID:20812517

2009-12-01

383

MANAGING WASTE AT LOS ALAMOS NATIONAL LABORATORY'S PLUTONIUM FACILITIES

Short communication. 1 ref., 4 figs.

384

Interstellar PAH Analogs in the Laboratory: Comparison with Astronomical Data

No abstract prepared.

2000-01-01

385

FY2003 Laboratory Directed Research and Development Program Annual Report

Polycyclic Aromatic Hydrocarbons (PAHs) are an important and ubiquitous component of carbon-bearing

2005-01-01

386

Automated transport and sorting system in a large reference laboratory: part 1. Evaluation of needs and alternatives and development of a plan.

No abstract prepared.

2004-07-30

387

PMID:12324492

2002-10-01

388

'__-_ _! _/_/ _

In 1963, Grover and co-workers at the Los Alamos. Scientific. Laboratory ...... and A. P. Watkins. (1986) "The Computation of Compressible ...

389

Zoonoses-With Friends Like This, Who Needs Enemies?

Health surveillance program This article outlines the principal components of quality control of laboratory rodents.

1986-02-01

390

X-ray structure of sensory rhodopsin II at 2.1-? resolution

Zoonoses are infections that are spread from animals to humans. Most often, humans are “dead-end” hosts, meaning that there is no subsequent human-to-human transmission. If one considers...Full Text Available

2008-01-01

391

Watchdog Calls on USDA to Boost Transparency in Organic Governance

Sensory rhodopsins (SRs) belong to a subfamily of heptahelical transmembrane proteins containing a retinal chromophore. These photoreceptors mediate the cascade of vision in animal eyes and phototaxis...Full Text Available

2001-08-28

392

Visually Mediated Odor Tracking During Flight in Drosophila

...qualified and who were under consideration at the time, USDA Secretary Tom Vilsack chose an animal husbandry specialist employed by one of the largest organic livestock product marketers in the country. While this appointee had grown up on a conventional farm, her immediate occupation is not that of ...

393

Variable Pathogenicity Determines Individual Lifespan in Caenorhabditis elegans

Flying insects use visual cues to stabilize their heading in a wind stream. Many animals additionally track odors carried in the wind. As such, visual stabilization of upwind tracking directly aids...Full Text Available

394

Two Proline-Rich Nuclear Localization Signals in the Amino- and Carboxyl-Terminal Regions of the Borna Disease Virus Phosphoprotein

A common property of aging in all animals is that chronologically and genetically identical individuals age at different rates. To unveil mechanisms that influence aging variability, we identified markers...Full Text Available

2011-04-01

395

Torpor induction in mammals: Recent discoveries fueling new ideas

Borna disease virus (BDV) uses a unique strategy of replication and transcription which takes place in the nucleus, unlike other known, nonsegmented, negative-stranded RNA viruses of animal origin....Full Text Available

1998-12-01

396

The pharmacology and molecular mechanisms underlying temperature regulation and torpor

When faced with a harsh climate or inadequate food, some mammals enter a state of suspended animation known as torpor. A major goal of torpor research is to determine mechanisms that integrate...Full Text Available

2009-12-01

397

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing

The ability to enter a hypometabolic state upon restriction of caloric intake is pivotal for animal survival: balancing the energy budget in endotherms can be a real struggle when food is not...Full Text Available

2008-10-01

398

The complete mitochondrial genome of the stomatopod crustacean Squilla mantis

Inhibiting insulin/IGF-1 signalling extends lifespan and delays age-related disease in species throughout the animal kingdom. This life-extension pathway, the first to be defined, was discovered through...Full Text Available

2011-01-12

399

The Potential Use of Electricity to Control Burrowing Shrimp in Oyster Aquaculture Beds

BackgroundAnimal mitochondrial genomes are physically separate from the much larger nuclear genomes and have proven useful both for phylogenetic studies and for understanding genome...Full Text Available

400

The Mitochondrial Isovaleryl-Coenzyme A Dehydrogenase of Arabidopsis Oxidizes Intermediates of Leucine and Valine Catabolism1

Thalassinid shrimp cause significant problems for oyster aquaculture in the Pacific Northwest (USA) where oysters succumb to the physical disruption of the sediment by the burrowing activity of these animals. While electrofishing is a commonly used technique to capture fish and some invertebrates i...

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401

Testing game theory models: fighting ability and decision rules in chameleon contests

We recently identified a cDNA encoding a putative isovaleryl-coenzyme A (CoA) dehydrogenase in Arabidopsis (AtIVD). In animals, this homotetrameric enzyme is located in mitochondria and catalyzes the...Full Text Available

2001-06-01

402

Sustained metabolic scope.

Game theory models of animal contests make many non-mutually exclusive predictions, complicating empirical tests. These predictions regard the relationship between contest parameters and fighting ability,...Full Text Available

2006-06-22

403

Study on upgrading of oil palm wastes to animal feeds by radiation and fermentation processing

Sustained metabolic rates (SusMR) are time-averaged metabolic rates that are measured in free-ranging animals maintaining constant body mass over periods long enough that metabolism is fueled by food...Full Text Available

1990-03-01

404

Stress and Stress-Induced Neuroendocrine Changes Increase the Susceptibility of Juvenile Oysters (Crassostrea gigas) to Vibrio splendidus

Upgrading of oil palm empty fruit bunch (EFB), which is a main by-product of palm oil industry, to animal feeds by radiation pasteurization and fermentation was investigated for recycling the agro-resources and reducing the environmental pollution. The following results were obtained: 1) The necessary dose for pasteurization of EFB contaminated by various microorganisms including aflatoxin producing fungi was determined as 10 kGy. The chemical and biological properties of EFB were changed little by irradiation up to 50 kGy. 2) In the fermentation process, Pleurotus sajor-caju was selected as the most effective fungi and the optimum condition for fermentation was clarified. The process of fermentation in suspension was also established for the liquid seed preparation. 3) The digestibility and nutritional value of fermented products were evaluated as ruminant animal feeds and the mushroom can be produced as by-product. 4) The pilot plant named ...

2002-10-15

405

Stable isotopes document the trophic structure of a deep-sea cephalopod assemblage including giant octopod and giant squid

Oysters are permanently exposed to various microbes, and their defense system is continuously solicited to prevent accumulation of invading and pathogenic organisms. Therefore, impairment of the animal's...Full Text Available

2001-05-01

406

Although deep-sea cephalopods are key marine organims, their feeding ecology remains essentially unknown. Here, we report for the first time the trophic structure of an assemblage of these animals (19...Full Text Available

2009-06-23

407

Some food toxic for pets

Shiga Toxin Subtypes Display Dramatic Differences in Potency ?

According to world statistics, dogs and cats are the species that owners most frequently seek assistance with potential poisonings, accounting 95–98% of all reported animal cases. Exposures...Full Text Available

2009-09-01

408

Scaling of swim speed and stroke frequency in geometrically similar penguins: they swim optimally to minimize cost of transport

Purified Shiga toxin (Stx) alone is capable of producing systemic complications, including hemolytic-uremic syndrome (HUS), in animal models of disease. Stx includes two major antigenic forms (Stx1...Full Text Available

2011-03-01

409

Scaling of offspring number and mass to plant and animal size: model and meta-analysis

It has been predicted that geometrically similar animals would swim at the same speed with stroke frequency scaling with mass^−1/3. In the present study, morphological and behavioural...Full Text Available

2010-03-07

410

Salmonellosis in Botswana

The scaling of reproductive parameters to body size is important for understanding ecological and evolutionary patterns. Here, we derived allometric relationships for the number and mass of seeds, eggs...Full Text Available

2008-04-01

411

Clinical salmonellosis in cattle is infrequently recorded in Botswana, the majority of salmonella isolations being made from apparently healthy animals. A salmonella carrier rate of 6·7% was...Full Text Available

1971-09-01

412

STR References 3001-3250

SG Report on Harmony with Nature final single-spaced.doc

Journal of Human Genetics. 82: 873-882. 3134. Schulz, I., Schneider, P. M., Olek, K, Rothschild, M. A., and Tsokos, M. (2006) Examination of Postmortem Animal Interference to Human...

2009-03-16

413

Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels

of early humanitarians, and the vivisectors turned to Rene Descartes (1596 1650 ) to justify ...A celebrated mathematician, physiologist, and psychologist, Descartes provided a general philosophy of the irrelevance of ethics to the ...Animals, according to Descartes, were insensible and irrational machines; moved, like clocks, but

414

Relations between respiratory symptoms and sickness among workers in the animal feed industry.

Phosphatidic acid (PA) is postulated to have both structural and signaling functions during membrane dynamics in animal cells. In this study, we show that before a critical time period during rhabdomere...Full Text Available

2009-04-06

415

Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit.

OBJECTIVE--The survey aimed at studying the associations between prevalent respiratory symptoms in an occupational population and sickness absence due to respiratory disorders. METHODS--A cross sectional...Full Text Available

1994-07-01

416

Receptor mechanisms and dose-response models for the effects of dioxins.

The effects of homologous plasma HDL and VHDL fractions on established atherosclerotic lesions were studied in cholesterol-fed rabbits. Atherosclerosis was induced by feeding the animals a 0.5% cholesterol-rich...Full Text Available

1990-04-01

417

Probing Compulsive and Impulsive Behaviors, from Animal Models to Endophenotypes: A Narrative Review

There is increasing evidence that receptor-mediated events impact one or more stages responsible for tumor development in experimental animals and humans. Although many chemicals and endogenous hormones...Full Text Available

1993-04-22

418

Prenatal cocaine reduces AMPA receptor synaptic expression through hyperphosphorylation of the synaptic anchoring protein GRIP

Failures in cortical control of fronto-striatal neural circuits may underpin impulsive and compulsive acts. In this narrative review, we explore these behaviors from the perspective of neural processes...Full Text Available

2010-02-01

419

Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity

Prenatal cocaine exposure produces sustained neurobehavioral and brain synaptic changes closely resembling those of animals with defective alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic...Full Text Available

2009-05-13

420

Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites.

How transcription factors interpret the cis-regulatory logic encoded within enhancers to mediate quantitative changes in spatiotemporally restricted expression patterns during animal...Full Text Available

2010-05-15

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421

Physiologic Responses to Infrarenal Aortic Cross-Clamping during Laparoscopic or Conventional Vascular Surgery in Experimental Animal Model: Comparative Study

Trichloroethylene (TCE) pharmacokinetics have been studied in experimental animals and humans for over 30 years. Compartmental and physiologically based pharmacokinetic (PBPK) models have been developed...Full Text Available

2000-05-01

422

Pathophysiological, Genetic and Gene Expression Features of a Novel Rodent Model of the Cardio-Metabolic Syndrome

The aim of this study was to compare the hemodynamic and ventilatory effects of prolonged infrarenal aortic cross-clamping in pigs undergoing either laparotomy or laparoscopy. 18 pigs were used for...Full Text Available

2008-01-01

423

Parallels between playbacks and Pleistocene tar seeps suggest sociality in an extinct sabretooth cat, Smilodon

BackgroundComplex etiology and pathogenesis of pathophysiological components of the cardio-metabolic syndrome have been demonstrated in humans and animal models.Methodology/Principal...Full Text Available

424

Outbreak of acute colitis on a horse farm associated with tetracycline-contaminated sweet feed.

Inferences concerning the lives of extinct animals are difficult to obtain from the fossil record. Here we present a novel approach to the study of extinct carnivores, using a comparison between fossil...Full Text Available

2009-02-23

425

On the function of the mammalian renal papilla and the peristalsis of the surrounding pelvis

Exposure of a group of horses to tetracycline-contaminated feed resulted in acute colitis and subsequent death in one horse and milder diarrhea in 3 others. The most severely affected animal demonstrated...Full Text Available

1999-10-01

426

Nuclear reprogramming in mammalian somatic cell nuclear cloning

This is an informal personal review of the development over time of my ideas about the concentrating mechanism of the mammalian renal papilla. It had been observed that animals with a need to produce...Full Text Available

2011-07-01

427

Novel Analogs and Stereoisomers of the Marine Toxin Neodysiherbaine with Specificity for Kainate Receptors

Nuclear cloning is still a developing technique used to create genetically identical animals by somatic cell nuclear transfer into unfertilized eggs. Despite an intensive effort in a number...Full Text Available

2004-01-01

428

Naturally occurring double-stranded RNA and immune responses. III. Immunogenicity and antigenicity in animals.

Antagonists for kainate receptors (KARs), a family of glutamate-gated ion channels, are efficacious in a number of animal models of neuropathologies, including epilepsy, migraine pain, and anxiety....Full Text Available

2008-02-01

429

Monitoring of Tumor Promotion and Progression in a Mouse Model of Inflammation-Induced Colon Cancer with Magnetic Resonance Colonography1

Naturally occurring, double-stranded RNA (ds-RNA)) was immunogenic when injected into mice, rats, guinea-pigs, rabbits, dogs and baboons. The response to native material administered intravenously (i.v.)...Full Text Available

1975-12-01

430

Mitochondrial DNA Damage and Animal Longevity: Insights from Comparative Studies

Early detection of precancerous tissue has significantly improved survival of most cancers including colorectal cancer (CRC). Animal models designed to study the early stages of cancer are valuable...Full Text Available

2009-03-01

431

Mechanical strain enhances survivability of collagen micronetworks in the presence of collagenase: implications for load-bearing matrix growth and stability

Chemical reactions in living cells are under strict enzyme control and conform to a tightly regulated metabolic program. However, uncontrolled and potentially deleterious endogenous reactions occur,...Full Text Available

432

Massive turnover of functional sequence in human and other mammalian genomes

There has been great interest in understanding the methods by which collagen-based load-bearing tissue is constructed, grown and maintained in vertebrate animals. To date, the responsibility for this...Full Text Available

2009-09-13

433

Major evolutionary transitions in ant agriculture

Despite the availability of dozens of animal genome sequences, two key questions remain unanswered: First, what fraction of any species' genome confers biological function, and second, are apparent...Full Text Available

2010-10-01

434

Longitudinal assessment of lung cancer progression in the mouse using in vivo micro-CT imaging

Agriculture is a specialized form of symbiosis that is known to have evolved in only four animal groups: humans, bark beetles, termites, and ants. Here, we reconstruct the major evolutionary transitions...Full Text Available

2008-04-08

435

Life history consequences of growth variation

Purpose: Small animal micro-CT imaging is being used increasingly in preclinical biomedical research to provide phenotypic descriptions of genomic models. Most of this imaging is coincident...Full Text Available

2010-09-01

436

Environmental Research Database

ObjectivesThe main objective of this study is to address the following specific questions: 1. Are the delayed effects of poor early diet on whole organism performance and senescence contingent on, or exacerbated by, the subsequent occurrence of compensatory growth? 2. Does the rate of growth influence levels of resting metabolism and/or oxidative stress, and if so, for how long does this persist? 3. How are the levels of early nutrition, growth, resting metabolism and oxidative stress linked to the lev [continued...]DescriptionIt is now widely appreciated that, while animals may appear to recover from periods of poor food quality or quantity experienced in early development, adverse effects may occur later in adult life. Such effects can influence the performance of complete cohorts of animals, and have important consequences for population dynamics. The reasons why such delayed effects occur across the animals' lifetimes ...

2009-01-30

437

Knockout of Arabidopsis ACCELERATED-CELL-DEATH11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense

Isolation of BAC Clones Containing Conserved Genes from Libraries of Three Distantly Related Moths: A Useful Resource for Comparative Genomics of Lepidoptera

We describe the lethal, recessive accelerated-cell-death11 Arabidopsis mutant (acd11). Cell death in acd11 exhibits characteristics of animal apoptosis...Full Text Available

2002-02-15

438

Inheritable Effect of Unpredictable Maternal Separation on Behavioral Responses in Mice

Lepidoptera, butterflies and moths, is the second largest animal order and includes numerous agricultural pests. To facilitate comparative genomics in Lepidoptera, we isolated BAC clones containing...Full Text Available

2011-01-01

439

Influence of parasite strain on chemotherapy of murine infections with schistosomiasis mansoni

The long-term impact of early stress on behavior and emotions is well documented in humans, and can be modeled in experimental animals. In mice, maternal separation during early postnatal development...Full Text Available

440

Influence of murine leukemia proviral integrations on development of N-methyl-N-nitrosourea-induced thymic lymphomas in AKR mice.

The effectiveness of chemotherapy in human schistosomiasis varies from one area to another, and limited data from experimentally infected animals suggest inherent differences in the susceptibility...Full Text Available

1971-01-01

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441

Importance of pollinators in changing landscapes for world crops

The AKR mouse strain is characterized by a high incidence of spontaneous thymic lymphoma that appears in older animals (greater than 6 months of age) and is associated with novel provirus integrations...Full Text Available

1991-11-01

442

Identification of environmental chemicals with estrogenic activity using a combination of in vitro assays.

The extent of our reliance on animal pollination for world crop production for human food has not previously been evaluated and the previous estimates for countries or continents have seldom used primary...Full Text Available

2007-02-07

443

ICC-MY coordinate smooth muscle electrical and mechanical activity in the murine small intestine

Environmental chemicals that function as estrogens have been suggested to be associated with an increase in disease and dysfunctions in animals and humans. To characterize chemicals that may act as...Full Text Available

1996-10-01

444

Hyperoxia enhances VEGF release from A549 cells via post-transcriptional processes

BackgroundAnimals carrying genetic mutations have provided powerful insights into the role of interstitial cells of Cajal (ICC) in motility. One classic model is...Full Text Available

2010-05-01

445

Hunting at the highway: traffic noise reduces foraging efficiency in acoustic predators

Exposure of animals to hyperoxia decreases lung VEGF mRNA expression concomitant with an acute increase in VEGF protein within the epithelial lining fluid (ELF). The VEGF concentration in ELF...Full Text Available

2007-09-01

446

Hsp12.6 Expression Is Inducible by Host Immunity in Adult Worms of the Parasitic Nematode Nippostrongylus brasiliensis

Noise pollution from human traffic networks and industrial activity impacts vast areas of our planet. While anthropogenic noise effects on animal communication are well documented, we have very limited...Full Text Available

2011-06-07

447

High stimulus specificity characterizes anti-predator habituation under natural conditions

Heat shock proteins (Hsp) are a family of stress-inducible molecular chaperones that play multiple roles in a wide variety of animals. However, the roles of Hsps in parasitic nematodes remain largely...Full Text Available

448

Health effects of air pollutants: sulfuric acid, the old and the new.

Habituation is one of the most fundamental learning processes that allow animals to adapt to dynamic environments. It is ubiquitous and often thought of as a simple form of non-associative learning....Full Text Available

2009-12-22

449

Gonadal hormones modulate sex differences in judgments of relative numerousness in meadow voles, Microtus pennsylvanicus

Data from exposure of experimental animals and human subjects to sulfuric acid presents a consistent picture of its toxicology. Effects on airway resistance in asthmatic subjects were well predicted...Full Text Available

1989-05-01

450

Glossary - Helmholtz-Centre for Environmental Research - UFZ - Research for the environment

Animals in a variety of taxa discriminate between a greater quantity and a lesser quantity of the same object, an ability that is referred to as relative numerousness judgment. For example,...Full Text Available

2009-01-01

451

Genotyping faecal samples of Bengal tiger Panthera tigris tigris for population estimation: A pilot study

... Contrary to this definition, abiotic environmental factors are those in which no organisms participate - e.g. the geological underground, light, temperature and heat. Biotope The biotope is an area of uniform environmental conditions providing living place for a specific assemblage of plants and animals....

452

Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens

BackgroundBengal tiger Panthera tigris tigris the National Animal of India, is an endangered species. Estimating populations for such species is the main objective...Full Text Available

453

Genome-Wide Identification and Evolutionary Analysis of the Animal Specific ETS Transcription Factor Family

The continued evolution of bacterial pathogens has major implications for both human and animal disease, but the exchange of genetic material between host-restricted pathogens is rarely considered....Full Text Available

2009-03-01

454

Genetic association between the COMT genotype and urinary levels of tea polyphenols and their metabolites among daily green tea drinkers

The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available

455

Gender and risk of autoimmune diseases: possible role of estrogenic compounds.

Available in vitro and animal studies have shown cancer protective effects of tea polyphenols. Recent study suggests a greater protective effect of green tea intake on breast cancer...Full Text Available

456

Fatty Acid- and Retinoid-binding Proteins Have Distinct Binding Pockets for the Two Types of Cargo*

A striking common feature of many autoimmune diseases in humans and experimental animals, despite differences in pathology, is that females are highly susceptible to autoimmune conditions compared to...Full Text Available

1999-10-01

457

Evolution of Thermal Response Properties in a Cold-Activated TRP Channel

Parasitic nematodes cause serious diseases in humans, animals, and plants. They have limited lipid metabolism and are reliant on lipid-binding proteins to acquire these metabolites from their hosts....Full Text Available

2009-12-18

458

Evidence for Diversity in Transcriptional Profiles of Single Hematopoietic Stem Cells

Animals sense changes in ambient temperature irrespective of whether core body temperature is internally maintained (homeotherms) or subject to environmental variation (poikilotherms). Here we show...Full Text Available

459

Evaluation of Tumor Micro-Environment in an Animal Model using a Nanoparticle Contrast Agent in Computed Tomography Imaging

Hematopoietic stem cells replenish all the cells of the blood throughout the lifetime of an animal. Although thousands of stem cells reside in the bone marrow, only a few contribute to blood production...Full Text Available

2006-09-01

460

Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester

RATIONALE AND OBJECTIVESNon-invasive longitudinal imaging of tumor vasculature could provide new insights into the development of solid tumors, facilitating efficient...Full Text Available

2011-01-01

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461

Epigenetic Therapies for Chemoresensitization of Epithelial Ovarian Cancer

Phenylpropenes such as chavicol, t-anol, eugenol, and isoeugenol are produced by plants as defense compounds against animals and microorganisms and as floral attractants of pollinators....Full Text Available

2006-06-27

462

Efficacy of antimicrobial therapy in experimental rat pneumonia: effects of impaired phagocytosis.

SummaryEpigenetic drugs have been shown to enhance gene expression and drug sensitivity in ovarian cancer cell lines and animal models. Based on promising pre-clinical studies,...Full Text Available

2010-02-01

463

Effect of dietary monosodium glutamate on trans fat-induced nonalcoholic fatty liver disease

The importance of intact host defense mechanisms for successful antimicrobial therapy was investigated in an animal model. Recovery from lobar pneumococcal pneumonia as a result of penicillin therapy...Full Text Available

1979-07-01

464

Early auditory experience generates long-lasting memories that may subserve vocal learning in songbirds

The effects of dietary monosodium glutamate (MSG) on trans-fatty acid (TFA)-induced nonalcoholic fatty liver disease (NAFLD) are addressed in an animal model. We used Affymetrix microarray...Full Text Available

2009-08-01

465

Display of Recombinant Proteins on Bacillus subtilis Spores, Using a Coat-Associated Enzyme as the Carrier?

In both humans and songbirds, infants learn vocalizations by imitating the sounds of adult tutors with whom they interact during an early sensitive period. Vocal learning occurs in few animal taxa;...Full Text Available

2006-01-24

466

Developmental plasticity and the evolution of animal complex life cycles

The display of proteins such as feed enzymes at the surface of bacterial spore systems has a great potential use for animal feed. Feed enzymes increase the digestibility of nutrients, leading to greater...Full Text Available

2010-09-01

467

Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.

Metazoan life cycles can be complex in different ways. A number of diverse phenotypes and reproductive events can sequentially occur along the cycle, and at certain stages a variety of developmental...Full Text Available

2010-02-27

468

Coordinated and Cohesive Movement of Two Small Conspecific Fish Induced by Eliciting a Simultaneous Optomotor Response

Vulnerable periods during the development of the nervous system are sensitive to environmental insults because they are dependent on the temporal and regional emergence of critical developmental processes...Full Text Available

2000-06-01

469

Conjugated linoleic acid modulation of risk factors associated with atherosclerosis

BackgroundIn animal groups such as herds, schools, and flocks, a certain distance is maintained between adjacent individuals, allowing them to move as a cohesive unit. Proximate...Full Text Available

470

Comparison of ante-mortem assays to assess progression/regression of paratuberculosis in individual dairy animals

Conjugated linoleic acid (CLA) has been the subject of extensive investigation regarding its possible benefits on a variety of human diseases. In some animal studies, CLA has been shown to have a beneficial...Full Text Available

471

Clostridium perfringens Delta Toxin Is Sequence Related to Beta Toxin, NetB, and Staphylococcus Pore-Forming Toxins, but Shows Functional Differences

Johne disease, caused by Mycobacterium avium, subspecies paratuberculosis (MAP) is becoming increasingly widespread on dairy farms worldwide, due in part, to the absence...Full Text Available

2010-05-01

472

Circadian Disruption and Metabolic Disease: Findings from Animal Models

Clostridium perfringens produces numerous toxins, which are responsible for severe diseases in man and animals. Delta toxin is one of the three hemolysins released by a number of C....Full Text Available

473

Chondroitin sulphate structure affects its immunological activities on murine splenocytes sensitized with ovalbumin

Social opportunities and work demands have caused humans to become increasingly active during the late evening hours, leading to a shift from the predominantly diurnal lifestyle of our ancestors...Full Text Available

2010-10-01

474

Chemical structure and inhalation toxicity of lipopolysaccharides from bacteria on cotton.

Chondroitin sulphate (CS) is a glycosaminoglycan widely distributed in animal tissues, which has anti-inflammatory and chondroprotective properties. We reported previously that chondroitin 4-sulphate...Full Text Available

2004-08-15

475

Chemical carcinogenesis: too many rodent carcinogens.

Lipopolysaccharides from different bacteria isolated from cotton were purified and chemically analyzed. Their pulmonary toxicity to animals was tested in inhalation tests. Lipopolysaccharides from Agrobacterium...Full Text Available

1980-09-01

476

Characterization of Toxin Plasmids in Clostridium perfringens Type C Isolates?

The administration of chemicals at the maximum tolerated dose (MTD) in standard animal cancer tests is postulated to increase cell division (mitogenesis), which in turn increases rates of mutagenesis...Full Text Available

1990-10-01

477

Central gating of fly optomotor response

Clostridium perfringens type C isolates cause enteritis necroticans in humans or necrotizing enteritis and enterotoxemia in domestic animals. Type C isolates always produce alpha toxin...Full Text Available

2010-11-01

478

Biphasic targeting and cleavage furrow ingression directed by the tail of a myosin II

We study the integration of multisensory and central input at the level of an identified fly motoneuron, the ventral cervical nerve motoneuron (VCNM) cell, which controls head movements of the animal....Full Text Available

2010-11-16

479

Biologic Rhythms Derived from Siberian Mammoths' Hairs

Cytokinesis in animal and fungal cells utilizes a contractile actomyosin ring (AMR). However, how myosin II is targeted to the division site and promotes AMR assembly, and how the AMR coordinates with...Full Text Available

2010-12-27

480

Beneficial Effect of a Short-Acting NO Donor for the Prevention of Neointimal Hyperplasia

Hair is preserved for millennia in permafrost; it enshrines a record of biologic rhythms and offers a glimpse at chronobiology as it was in extinct animals. Here we compare biologic rhythms gleaned...Full Text Available

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481

Behavioral consequences of dopamine deficiency in the Drosophila central nervous system

Nitric oxide (NO)-based therapies effectively inhibit neointimal hyperplasia in animal models of arterial injury and bypass grafting, but are not available clinically. We created a simple, effective,...Full Text Available

2008-01-01

482

Associations between the clinical signs of chronic endometritis with ovarian cysts and body condition loss in German Holstein Friesian cows

The neuromodulatory function of dopamine (DA) is an inherent feature of nervous systems of all animals. To learn more about the function of neural DA in Drosophila, we generated mutant...Full Text Available

2011-01-11

483

Assessing phytoremediation potentials of selected tropical plants for acrylamide

The objective of this retrospective field study was to associate the type and smell of discharge, the size of the uterus, the ovarian and treatment status, and the time to diagnosis of animals with...Full Text Available

2009-12-01

484

Arabidopsis thaliana Chromosome 4 Replicates in Two Phases That Correlate with Chromatin State

In biotechnology, acrylamide is being used in DNA and RNA analysis using the polyacrylamide gel electrophoreses procedure. Polymerized acrylamide is degraded into acrylamide through time; it is converted into a hazardous contaminant that is carcinogenic and neurotoxic to animals and humans. Because ...

485

Animal and human studies of a new /sup 99m/Tc labelled phosphine-isocyanide complex with possible applications to radionuclide ventriculography

DNA replication programs have been studied extensively in yeast and animal systems, where they have been shown to correlate with gene expression and certain epigenetic modifications. Despite the conservation...Full Text Available

2010-06-01

486

Animal Models in Carotenoids Research and Lung Cancer Prevention1

A new /sup 99m/Tc-phosphine-isocyanide complex with the general structure (/sup 99m/Tc (DEPE)/sub 2/(CNR)/sub 2/)/sup +/ has been synthesised and tested in animals and one human. In three animal species (rat, rabbit, dog), the complex is an efficient myocardial imaging agent, while in humans it remains in the blood pool. The complex is 100% protein bound in animals and humans, but whereas in humans it is attached to a 51.5 kdalton protein (probably prealbumin), in rabbits it appears to be bound to a larger macromolecule (M.W.>100 kdalton). The efficiency of the complex for blood pool labelling was tested in a human volunteer and compared with the standard in vivo red cell labelling technique with stannous pyrophosphate. A satisfactory radionuclide angiogram could be performed with less than 370 MBq of the complex. The count rate for the complex (cps/MBq) was 15% higher than that obtained with the labelled red cells and ...

1987-04-01

487

Analysis of the Pharmacokinetic Interaction between Cephalexin and Quinapril by a Nonlinear Mixed-Effect Model

Numerous epidemiological studies have consistently demonstrated that individuals who eat more fruits and vegetables (which are rich in carotenoids) and who have higher serum β-carotene levels...Full Text Available

488

An initial comparative map of copy number variations in the goat (Capra hircus) genome

Oligopeptidic drugs such as β-lactams and angiotensin-converting enzyme inhibitors share the same carriers in humans and animals, which results in possible pharmacokinetic interactions. To model...Full Text Available

1998-06-01

489

An argument for the chicken embryo as a model for the developmental toxicological effects of the polyhalogenated aromatic hydrocarbons (PHAHs)

BackgroundThe goat (Capra hircus) represents one of the most important farm animal species. It is reared in all continents with an estimated world population of...Full Text Available

490

An Intrinsic Neuronal Oscillator Underlies Dopaminergic Neuron Bursting

This article will present the argument that the chicken embryo is especially appropriate as an animal model for studying the mechanism of the developmental toxicological effects of the polyhalogenated aromatic hydrocarbons (PHAHs). The PHAHs are a group of toxicologically related compounds including, in part, the polychlorinated dibenzodioxins, dibenzofurans and biphenyls. The chicken (Gallus gallus) embryo is relatively sensitive to the toxicological effects of the PHAHs being approximately two orders of magnitude more sensitive than the mature bird. The chicken embryo has been used to demonstrate general toxicological teratogeneicity, hepatotoxicity and neurotoxicity. Many of these effects, or analogous effects, have also been observed in mammals and fish. Thus, most animals appear to respond to the PHAHs with a similar toxicological profile, indicating that many of the biomarkers used for the PHAHs are valid across a number of species, ...

1996-12-31

491

Allometry of visceral organs in living amniotes and its implications for sauropod dinosaurs

Dopaminergic neurons of the ventral midbrain fire high frequency bursts when animals are presented with unexpected rewards, or stimuli that predict reward. To identify the afferents that can...Full Text Available

2009-12-16

492

Acamprosate and naltrexone treatment effects on ethanol and sucrose seeking and intake in ethanol-dependent and nondependent rats

Allometric equations are often used to extrapolate traits in animals for which only body mass estimates are known, such as dinosaurs. One important decision can be whether these equations should be...Full Text Available

2009-05-07

493

A Novel Mouse Model of Red Blood Cell Storage and Post-Transfusion in Vivo Survival

RationaleTwo pharmacotherapies are approved for treating alcohol craving (acamprosate and naltrexone), but both have shown mixed findings in animals and humans.Full Text Available

2009-06-01

494

A Meta-Analysis of Animal Studies on Disruption of Spatial Navigation by Prenatal Cocaine Exposure

BackgroundStorage of RBCs is necessary for an adequate blood supply. However, reports have identified potential negative sequelae of transfusing stored RBCs. An animal...Full Text Available

2009-08-01

495

A Dominant Role for the Immunoproteasome in CD8⁺ T Cell Responses to Murine Cytomegalovirus

Water-maze testing has been used to assess prenatal cocaine (PCOC)- induced deficits in behavioral studies of spatial navigation and memory abilities. Effects of PCOC in acquisition or in probe...Full Text Available

2007-01-01

496

32 CFR 935.40 - Criminal offenses.

Murine cytomegalovirus (MCMV) is an important animal model of human cytomegalovirus (HCMV), a β-Herpesvirus that infects the majority of the world's population and causes disease in neonates...Full Text Available

497

32 CFR 935.150 - Registration.

... (v) Import onto or keep on Wake Island any plant or animal not indigenous to the island, other than military working dogs or a guide dog for the blind or visually-impaired accompanying its owner; or (w) Import or bring onto or...

2010-07-01

498

...1) A privately owned motor vehicle. (2) A privately owned boat. (3) An indigenous animal, military working dog, or guide dog for the blind or visually-impaired accompanying its owner. (4) A narcotic or dangerous drug or...

2010-07-01

499

27na4

Analysis of medicinal plant extracts by neutron activation method; Analise de extratos de plantas medicinais pelo metodo de ativacao com neutrons

by American scientists, ecosystems containing a greater number of plant species, produce more biomass.This result ...to meet the increasing demand for land for farmland planted with monocultures, buildings and roads.For ...have hypothesized that greater ecological diversity (diversity of plant and animal species) leads to a greater

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