UK PubMed Central (United Kingdom)

Essential in mitosis, the human Kinesin-5 protein is a target for >80 classes of allosteric compounds that bind to a surface-exposed site formed by the L5 loop. Not established is why there...Full Text Available

UK PubMed Central (United Kingdom)

We have measured the forward and reverse rates of the allosteric transition of hemoglobin A with three CO molecules bound by using modulated excitation coupled with fluorescence quenching of the DPG...Full Text Available

International Nuclear Information System (INIS)

High-resolution proton nuclear magnetic resonance spectroscopy has been used to investigate the molecular mechanism of the Bohr effect of human normal adult hemoglobin in the presence of two allosteric effectors, i.e., chloride and inorganic phosphate ions. The individual hydrogen ion equilibria of 22-26 histidyl residues of hemoglobin have been measured in anion-free 0.1 M HEPES buffer and in the presence of 0.18 M chloride or 0.1 M inorganic phosphate ions in both deoxy and carbonmonoxy forms. The results indicate that the #beta#2-histidyl residues are strong binding sites for chloride and inorganic phosphate ions in hemoglobin. The affinity of the #beta#2-histidyl residues for these anions is larger in the deoxy than in the carbonmonoxy form. Nevertheless, the contribution of these histidyl residues to the anion Bohr effect is small due to their low pK value in deoxyhemoglobin in anion-free solvents. The interactions of chloride and ...

UK PubMed Central (United Kingdom)

Metabotropic glutamate receptor 2/3 (mGluR2/3) agonists were shown previously to nonselectively decrease both cocaine- and food-maintained responding in rats. mGluR2 positive allosteric modulators (PAMs)...Full Text Available

UK PubMed Central (United Kingdom)

The mechanism by which enzyme IIIglc of the bacterial phosphotransferase system regulates the activity of crystalline glycerol kinase from Escherichia coli has been studied, and the inhibitory effects...Full Text Available

International Nuclear Information System (INIS)

The 2- and 8-azido trimer 5'-triphosphate photoprobes of 2-5A have been enzymatically synthesized from [#gamma#-"3"2P]2-azidoATP and [#alpha#-"3"2P]8-azidoAPT by 2-5A synthetase from rabbit reticulocyte lysates. Identification and structural determination of the 2- and 8-azido adenylate trimer 5'-triphosphates were accomplished by enzymatic hydrolyses with T2 RNase, snake venom phosphodiesterase, and bacterial alkaline phosphatase. Hydrolysis products were identified by HPLC and PEI-cellulose TLC analyses. The 8-azido photoprobe of 2-5A displaces p_3A_4["3"2P]pCp from RNase L with affinity equivalent to p_3A_3. The 8-azido photoprobe also activates RNase L to hydrolyze poly(U)["3"2P]pCp 50% at 7 /times/ 10/sup /minus/9/ M in core-cellulose assays. The 2- and 8-azido photoprobes and authentic p_3A_3 activate RNase L to cleave 28S and 18S rRNA to specific cleavage products at 10/sup /minus/9/ M in rRNA cleavage assays. The nucleotide binding site(s) of RNase L and/or ...

UK PubMed Central (United Kingdom)

Most genetic changes that promote tumorigenesis involve dysregulation of G1 cell cycle progression. A key regulatory site in G1 is a growth factor–dependent restriction point (R) where cells...Full Text Available

Wastenet

...Project objectives to restore/create network of secure lapwing breeding sites to provide conservation management advice to planners, developers and land managers to raise awareness of lapwing conservation issues in the local areaKey dates so far First pair of lapwing breeding at Parc Bryn Bach, mitigation site for loss of a nearby large lapwing breeding colony, in May 2008Work planned or underway Continued working with developers and landowners to ...

International Nuclear Information System (INIS)

The U.S. Department of Energy (DOE) has developed comparatively detailed quality assurance requirements for the high-level radioactive waste disposal systems. Quality assurance is recognized as a key issue for confidence building and smooth implementation of the HLW program in Japan, and Japan is at an initial phase of repository development. Then the quality assurance requirements at site research and site selection, site characterization, and site suitability analysis used in the Yucca Mountain project were examined in detail and comprehensive descriptions were developed using flow charts. Additionally, the applicability to the Japan high-level radioactive waste disposal project was studied. The examination and study were performed for the following QA requirements: The requirements that have the relative importance at site research and ...

Energy Technology Data Exchange (ETDEWEB)

The Department of Energy's National Solar Data Program established solar energy systems in residential and commercial buildings across the United States. These solar sites are linked to Vitro Laboratories Division's computer in the National Solar Data Network (NSDN). Vitro collects and analyzes data from this network to determine the thermal performance of each of the solar systems. The network consists of: (1) sensors which measure key performance parameters at a selected site; (2) a Site Data Acquisition Subsystem (SDAS); (3) telephone transmission circuits; and (4) a Central Data Processing System (CDPS). For the majority of parameters, raw data is collected approximately every five minutes. Solar insolation and certain other parameters, which are subject to rapid variance, are sampled every 32 seconds. Environmental information collected at the sites for the ...

Wastenet

... News In Practice UK work Key facts & information Mass Balance Projects Resources & Library Technical Area Contacts Site Map Benchmarking solvent waste in the UK furniture manufacturing industry OrganisationBritish Furniture Manufacturers Ltd Project ReportSolvent Waste in Furniture Manufacturing Website: www.bfmenvironment.co.uk Return to list � RSWT | Website Design Quiet Storm Solutions Ltd Please consider upgrading your browser! If you can see this ...

Energy Technology Data Exchange (ETDEWEB)

The Savannah River Site (SRS) is a key installation for the production and research of nuclear materials for national defense and peace time applications and has been operating a full nuclear fuel cycle since the early 1950s. Wastes generated include high level radioactive, transuranic, low level radioactive, hazardous, mixed, sanitary, and aqueous wastes. Much progress has been made during the last several years to reduce these wastes including management systems, characterization, and technology programs. The reduction of wastes generated and the proper handling of the wastes have always been a part of the Site's operation. This paper summarizes the current status and future plans with respect to waste reduction to waste reduction and reviews some specific examples of successful activities.

British Library Electronic Table of Contents (United Kingdom)

Fitness, (biometric measurements, reproduction) and behaviour that are ecologically relevant biomarkers in assessing the quality of estuarine sediments were studied by comparing the responses of the polychaete worm Nereis diversicolor - a key species in estuaries - along a pollution gradient. Intersite differences were shown for all the measured parameters: size-weight relationships, energy reserves as glycogen and lipids, sexual maturation patterns, total number of oocytes per female, total and relative fecundity, burrowing behaviour. The physiological and behavioural status of N. diversicolor was consistently disturbed in the larger, most contaminated estuaries (Loire and Seine, Fr.) compared to reference sites (Bay of Bourgneuf, Goyen estuary, Fr.). Many classes of potentially toxic che...

Energy Technology Data Exchange (ETDEWEB)

North Carolina is in the process of siting a LLRW disposal facility as the next host state for the Southwest Compact. After two years of site characterization studies at two technically challenging sites, the LLRW Management Authority (the Authority), will submit a license application for the preferred site. One potential site is in unconsolidated Tertiary and Cretaceous deposits of the inner Coastal Plain, the other in fractured sedimentary rocks of the Triassic Deep River Basin. Involved since 1986, the North Carolina Geological Survey (NCGS) provides technical advice to the Division of radiation Protection, the state regulatory agency authorized to approve or deny a license. With the multi-million dollar project behind schedule, and millions of dollars over budget, in February 1992 the Southeast Compact Commission established three project milestones (1) submit license ...

Energy Technology Data Exchange (ETDEWEB)

The purpose is to describe problems associated with the establishment of vegetation on mined lands and practical rehabilitation and restoration methods for establishing a rehabilitation plan. Land disturbed by mining should be restored to its original state, when the mine is decommissioned, but before that can be attained, site problems such as toxicity, moisture supply, and texture must be rectified. The land may need to pass through several conditioning stages, and links need to be formed to maintain a functioning ecosystem. A key aspect to rehabilitation is the need to increase the organic matter content of the substrate. This improves soil structure, increases the moisture holding ability, and provides a pool for nutrient cycling. 11 refs., 2 tabs.

Energy Technology Data Exchange (ETDEWEB)

This document presents a detailed schedule for the implementation of the strategy for managing defense remote-handled (RH) transuranic (TRU) waste. The baseline management strategy was defined in the Defense Remote-Handled Transuranic Waste Cost/Schedule Optimization Study and is summarized in this document. Also included are revised RH TRU waste inventory projections, current site management plans, a list of key decision points and milestones, and a discussion of uncertainties associated with management of RH TRU waste. The plans are summarized in a detailed schedule diagram and in an RH TRU waste work off diagram. 9 refs., 5 figs., 4 tabs.

CERN Document Server

We study the structure of the medium surrounding sites of high-mass star formation to determine the interrelation between the HII regions and the environment from which they were formed. The density distribution of the surroundings is key in determining how the radiation of the newly formed stars interacts with the surrounds in a way that allows it to be used as a star formation tracer. We present new Herschel/SPIRE 250, 350 and 500 mum data of LHA 120-N44 and LHA 120-N63 in the LMC. We construct average spectral energy distributions (SEDs) for annuli centered on the IR bright part of the star formation sites. The annuli cover ~10-~100 pc. We use a phenomenological dust model to fit these SEDs to derive the dust column densities, characterise the incident radiation field and the abundance of polycyclic aromatic hydrocarbon molecules. We see a factor 5 decrease in the radiation field energy density as a function of radial ...

Energy Technology Data Exchange (ETDEWEB)

The U.S. Department of Energy (DOE) Headquarters and associated contractors have developed an IBM PC-based software package that estimates costs, schedules, and public and occupational health risks for a range of mixed-waste management options. A key application of the software package is the comparison of various waste-treatment options documented in the draft Site Treatment Plans prepared in accordance with the requirements of the Federal Facility Compliance Act of 1992. This automated Systems Analysis Methodology consists of a user interface for configuring complexwide or site-specific waste-management options; calculational algorithms for cost, schedule and risk; and user-selected graphical or tabular output of results. The mixed-waste management activities modeled in the automated Systems Analysis Methodology include waste storage, characterization, handling, transportation, treatment, and disposal. Analyses of ...

International Nuclear Information System (INIS)

This paper summarizes the progress to date by CH2M HILL and the UKAEA in development of a parametric modelling capability for estimating the costs of large nuclear decommissioning projects in the United Kingdom (UK) and Europe. The ability to successfully apply parametric cost estimating techniques will be a key factor to commercial success in the UK and European multi-billion dollar waste management, decommissioning and environmental restoration markets. The most useful parametric models will be those that incorporate individual components representing major elements of work: reactor decommissioning, fuel cycle facility decommissioning, waste management facility decommissioning and environmental restoration. Models must be sufficiently robust to estimate indirect costs and overheads, permit pricing analysis and adjustment, and accommodate the intricacies of international monetary exchange, currency fluctuations and contingency. The development of a parametric cost ...

International Nuclear Information System (INIS)

During 1994 and the early part of 1995, the US Department of Energy's Yucca Mountain Site Characterization Office (YMSCO) and its parent organization, the Office of Civilian Radioactive Waste Management (OCRWM) underwent a significant restructuring. Senior Department officials provided the leadership to reorient the management, technical, programmatic, and public interaction approach to the US High Level Radioactive Waste Disposal Program. The restructuring involved reorganizing the federal staff, conducting meaningful strategic planning, improving the management system, rationalizing contractor responsibilities, focusing upon major products, and increasing stakeholder involvement. The restructured program has prioritized technical and scientific activities toward meeting major regulatory milestones in a timely and cost-effective manner. This approach has raised concern among elements of technical, scientific, and oversight bodies that suitability and licensing ...

International Nuclear Information System (INIS)

The Steam Generator (SG) tubing degradation caused by corrosion and other age-related mechanisms continues to be a significant safety and cost concern for many Nuclear Power Plants (NPP). The understanding of the steam generator ageing mechanisms is the key to effective management of steam generator ageing and consists of the knowledge of steam generator materials and these one properties, stressors and operating conditions, like degradation sites and wear mechanisms. The principal types of corrosion are presented which can occur in CANDU steam generator. There are also presented the operation conditions, the specifications referring to the water chemistry and the construction materials of Steam Generator, the factors that have a great influence on the corrosion behaviour during the whole exploitation period of this equipment. (R.P.)

British Library Electronic Table of Contents (United Kingdom)

The objective of this work was to compare seasonal variations of reproduction physiology of the ragworm Nereis diversicolor -a key species in estuarine ecosystems-originating from a clean (Authie) and multi-polluted (Seine) estuaries. A particular attention was carried out in female worms, on relationships between sexual maturity stages, energy reserves (glycogen and lipids) and steroid hormone levels (progesterone, 17b-estradiol, and testosterone). Sexual maturity index (SMI), energy reserves and steroid hormones are clearly influenced by season in worms from both sites. Depleted steroid hormone levels were depicted in specimens exhibiting high sexual maturity stage and energy reserves. Intersite analysis has revealed all over the sampling period:-a sexual precocity in worms from Seine,-g...

Energy Technology Data Exchange (ETDEWEB)

This report presents the results of an assessment of uranium in situ leach mining costs through the application of process engineering and discounted cash flow analysis procedures. A computerized costing technique was developed to facilitate rapid cost analyses. Applications of the cost model will generate mine life capital and operating costs as well as solve for economic production cost per pound U/sub 3/O/sub 8/. Conversely, rate of return may be determined subject to a known selling price. The data bases of the cost model were designed to reflect variations in Texas versus Wyoming site applications. The results of applying the model under numerous ore deposit, operating, well field, and extraction plant conditions for Texas and Wyoming are summarized in the report. Sensitivity analysis of changes in key project parameters have also been tested and are included.

Energy Technology Data Exchange (ETDEWEB)

This document, which is prepared as directed by the Compliance Order on Consent (COOC) issued by the New Mexico Environment Department, identifies and outlines a process to evaluate remedial alternatives to identify a corrective measure for the Sandia National Laboratories/New Mexico Technical Area (TA)-V Groundwater. The COOC provides guidance for implementation of a Corrective Measures Evaluation (CME) for the TA-V Groundwater. This Work Plan documents an initial screening of remedial technologies and presents a list of possible remedial alternatives for those technologies that passed the screening. This Work Plan outlines the methods for evaluating these remedial alternatives and describes possible site-specific evaluation activities necessary to estimate remedy effectiveness and cost. These methods will be reported in the CME Report. This Work Plan outlines the CME Report, including key components and a description of the corrective ...

Energy Technology Data Exchange (ETDEWEB)

To monitor the groundwater contamination and the effectiveness of remedial actions, over a thousand monitoring wells are in active operation (i.e., require quarterly or semi-annual sampling) at SRS. Most wells are expected to continue in operation for another 20 to 40 more years. Required sample volumes can range from a less than a liter to 10 liters. To support the long-term groundwater monitoring requirements of these wells, SRS actively seeks technologies that can maximize data acquisition and minimize costs. To meet this end, SRS has implemented the Purge Water Management System (PWMS). The key attributes of this system lie in its ability to reduce or eliminate the generation of purged groundwater, which is costly in terms of the time and management.

DEFF Research Database (Denmark)

Udgivelsesdato: winter

Energy Technology Data Exchange (ETDEWEB)

Managing sites contaminated with munitions constituents is an international challenge. Although the choice of approach and the use of Ecological Risk Assessment (ERA) tools may vary from country to country, the assurance of quality and the direction of ecotoxicological research are universally recognized as shared concerns. Drawing on a multidisciplinary team of contributors, 'Ecotoxicology of Explosives' provides comprehensive and critical reviews available to date on fate, transport, and effects of explosives. The book delineates the state of the science of the ecotoxicology of explosives, past, present, and recently developed. It reviews the accessible fate and ecotoxicological data for energetic materials (EMs) and the methods for their development. The chapters characterize the fate of explosives in the environment, then provide information on their ecological effects in key environmental media, including aquatic, ...

CERN Document Server

Aerial view of CERN with the LHC sites.

British Library Electronic Table of Contents (United Kingdom)

Molecular recognition by calix[6]arene-based receptors bearing three primary alkylamino side chain arms (1) is described. Complexation of ZnII ion provides the dinuclear m-hydroxo complex ${{\\bf 2}{{{\\rm OH}\\hfill \\atop {\\rm G}\\hfill}}}$, XRD characterization of which, together with solution studies, provided evidence of its hosting of neutral polar organic guests G. Treatment of this complex with a carboxylic acid or a sulfonamide (XH) results in the formation of mononuclear species ${{\\bf 3}{{{\\rm X}\\hfill \\atop {\\rm G}\\hfill}}}$, one of which (X = Cl) has been characterized by XRD. A dicationic complex ${{\\bf 3}{{{\\rm RNH}{_{2}}\\hfill \\atop {\\rm G}\\hfill}}}$ is obtained upon treatment of ${{\\bf 2}{{{\\rm OH}\\hfill \\atop {\\rm G}\\hfill}}}$ with a mixture of an alkylamine and a strong acid....

Energy Technology Data Exchange (ETDEWEB)

As regards the environmental protection, the A.C.R.O. maintained in 2001 its programs of surveillance around the main western nuclear installations of France. The radioecological surveillance of the site of Cogema La-Hague for the dismantling of the former pipe of release in sea was one of the key points of this action environmental surveillance. The two accidents of atmospheric release in may and october 2001 at Cogema La Hague have shown the interest of an association as A.C.R.O.. It is thank to the measure, by our laboratory, of repercussions on environment of these incidents that it has been possible to bring to light a dysfunction of the measurement system of the gaseous effluents released by the facility operator. To improve the public information, A.C.R.O. concerns its main efforts on the development of the consumer technical information available on-line via its web site and in its regular publication 'the ...

CERN Document Server

In key management schemes that realize secure multicast communications encrypted by group keys on a public network, tree structures are often used to update the group keys efficiently. Selcuk and Sidhu have proposed an efficient scheme which updates dynamically the tree structures based on the withdrawal probabilities of members. In this paper, it is shown that Selcuk-Sidhu scheme is asymptotically optimal for the cost of withdrawal. Furthermore, a new key management scheme, which takes account of key update costs of joining in addition to withdrawal, is proposed. It is proved that the proposed scheme is also asymptotically optimal, and it is shown by simulation that it can attain good performance for nonasymptotic cases.

International Nuclear Information System (INIS)

The Mixed Waste Management Facility, or MWMF, has been proposed as a national testbed facility for the demonstration and evaluation of technologies that are alternatives to incineration for the treatment of mixed low-level waste. The facility design will enable evaluation of technologies at pilot scale, including all aspects of the processes, from receiving and feed preparation to the preparation of final forms for disposal. The MWMF will reduce the risk of deploying such technologies by addressing the following: (1) Engineering development and scale-up. (2) Process integration and activation of the treatment systems. (3) Permitting and stakeholder issues. In light of the severe financial constraints imposed on the DOE and federal programs, DOE/HQ requested a study to assess the cost benefit for the MWMF given other potential alternatives to meet waste treatment needs. The MVVMF Project was asked to consider alternatives specifically associated with commercialization and privatization ...

Energy Technology Data Exchange (ETDEWEB)

The construction and use of a portable, microprocessor controlled anodic stripping voltameter for on-site simultaneous metal analysis of copper, lead and cadmium in tap water is discussed. The instrumental system is comprised of a programmable controller which permits keying in analytical parameters such as sparge time and plating time: a rotating cell for efficient oxygen removal and amalgam formation; and, data handling via a minicomputer or analog pen recorder. Plating and stripping potentials are controlled by a digital potentiostat; stripping is done using a staircase waveform with measurement of the current after a one msec delay. In this way charging current effects are minimized. Results of tap water analysis showed 3 +- 1 ..mu..g/L lead, 22 +- 0.3 ..mu..g/L copper, and less than 0.2 ..mu..g/L cadmium for a Berkeley, California tap water, and 1-1000 ..mu..g/L Cu, 1 -2 ..mu..g/L Pb for ten samples of Seattle, Washington tap water. ...

International Nuclear Information System (INIS)

The 105-KE and 105-KW Fuel Storage Basins were constructed more than 35 years ago as repositories for irradiated fuel from the K East and K West Reactors. Currently, the basins contain irradiated fuel from the N Reactor. To continue to use the basins as desired, seismic adequacy in accordance with current US Department of Energy facility requirements must be demonstrated. The 105-KE and 105-KW Basins are reinforced concrete, belowground reservoirs with a 16-ft water depth. The entire water retention boundary, which currently includes a portion of the adjacent reactor buildings, must be qualified for the Hanford Site design basis earthquake. The reactor building interface joints are sealed against leakage with rubber water stops. Demonstration of the seismic adequacy of these interface joints was initially identified as a key issue in the seismic qualification effort. The issue of water leakage through seismicly induced cracks was also ...

Energy Technology Data Exchange (ETDEWEB)

There are certain factors to take into account when determining the suitability of a healthy house site. Power lines, agricultural spraying, vehicle exhaust, and industrial pollution are all potential sources of indoor air contamination. It is recommended that a environmental assessment be done to determine whether there are specific sources of contamination. Good drainage is required. The surrounding landscaping should be open and sunlit, and with low maintenance requirements. Decks and fences made from pressure-treated or chemical treated lumber should be avoided. One of the early decisions in the design process is the choice of the structural system. The key with all foundation types is to control moisture, whether from rain, from the ground, or the condensation of moisture from the air with cooling. The construction frame is sealed away from the occupants by the air/vapor barrier, so only in extreme cases is it essential to use alternatives ...

International Nuclear Information System (INIS)

The purpose of this paper is to evaluate a complete set of environmental pathways for disposal options and conditions that the Nuclear Regulatory Commission (NRC) may analyze for a low-level radioactive waste (LLW) license application. The regulations pertaining In the past, shallow-land burial has been used for the disposal of low-level radioactive waste. However, with the advent of the State Compact system of LLW disposal, many alternative technologies may be used. The alternative LLW disposal facilities include below- ground vault, tumulus, above-ground vault, shaft, and mine disposal This paper will form the foundation of an update of the previously developed Sandia National Laboratories (SNL)/NRC LLW performance assessment methodology. Based on the pathway assessment for alternative disposal methods, a determination will be made about whether the current methodology can satisfactorily analyze the pathways and phenomena likely to be important for the full range of potential ...

Energy Technology Data Exchange (ETDEWEB)

A family of mixed LiCo{sub y}Ni{sub (1-y)}VO{sub 4} (y=0.2, 0.5 and 0.8) compounds of potential use as high voltage cathode materials in lithium batteries, has been synthesized and characterized. The X-ray diffraction analysis showed that these compounds adopt an inverse spinel structure where in average 85% of the Ni{sup 2+} and Co{sup 2+} ions occupy octahedral sites and the other 15% occupy tetrahedral sites with the V{sup 5+} ions, although this occupation share is somewhat influenced by the preparation temperature. The annealing temperature plays also a key role in determining the particle size, as demonstrated by scanning electron microscope analysis. Cycling voltammetry tests showed that the lithium insertion-deinsertion process in the LiCo{sub y}Ni{sub (1-y)}VO{sub 4} electrode materials occurs reversibly around 4.3-4.4 V vs. Li, as also confirmed by cycling tests. The cycling capacity is somewhat modest; however, ...

DEFF Research Database (Denmark)

Promoted as the first academic conference to be held completely in graphical cyberspace, Avatars 98 took place in November 1998. The virtual conference site was built and inhabited using software that supports multi-party presence over the Internet in a simulated, navigable environment. During the conference, avatar-embodied speakers using text chat performed to virtual audiences, 'webcams' (re)broadcast live video images of CNN and other remote sites, and a 'webcast' sent audiovisual representations captured by video camera of certain key participants in their physical locations. Such a novel and spectacular multi-media event raises many questions. How do we conceive of the recent developments in media technology and social computing that are impacting on what we have traditionally called 'the mass media'? How is interaction and talk mediated and adapted to new media genres? And how do participants construct and maintain ...

Energy Technology Data Exchange (ETDEWEB)

Geologic sequestration represents a promising strategy for isolating CO{sub 2} waste streams from the atmosphere. Successful implementation of this approach hinges on our ability to predict the relative effectiveness of subsurface CO{sub 2} migration and sequestration as a function of key target-formation and cap-rock properties, which will enable us to identify optimal sites and evaluate their long-term isolation performance. Quantifying this functional relationship requires a modeling capability that explicitly couples multiphase flow and kinetically controlled geochemical processes. We have developed a unique computational package that meets these criteria, and used it to model CO{sub 2} injection at Statoil's North-Sea Sleipner facility, the world's first saline-aquifer storage site. The package integrates a state-of-the-art reactive transport simulator (NUFT) with supporting geochemical software and ...

International Nuclear Information System (INIS)

Literature on examples of phytoremediation techniques used in the in-situ remediation of soils contaminated by petroleum hydrocarbons is reviewed. The review includes discussion of the key mechanisms involved in each case, benefits, limitations and costs compared to alternative approaches, including natural attenuation, engineering and bioremediation. Review of the literature led to the conclusion that phytoremediation is an effective method for degrading and containing petroleum hydrocarbons in soil, and confirmed the ability of plants to transfer volatile petroleum hydrocarbons, such as napthalene, from the soil to the atmosphere via transpiration. The primary loss mechanism for the degradation of petroleum hydrocarbons appears to be microorganisms in the rhizosphere of plants. The available information also suggests that plants may degrade petroleum hydrocarbons directly, although the indirect role played by plants is far more common. These roles include ...

British Library Electronic Table of Contents (United Kingdom)

Strategic management of key accounts has become an important component of many companies' sales efforts. This research introduces a strategic framework of key account performance that integrates theory from relationship marketing, key account management, and customer equity. Using the three drivers of customer equity - value equity, brand equity, and relationship equity - the framework captures both the relational outcomes (relationship commitment and trust) and financial performance outcomes (profitability and share of spend) of strategic decisions made in key account programs. Implications and future research are then discussed.

Energy Technology Data Exchange (ETDEWEB)

The Office of Environmental Management's (EM) Roadmap, U.S. Department of Energy--Office of Environmental Management Engineering & Technology Roadmap (Roadmap), defines the Department's intent to reduce the technical risk and uncertainty in its cleanup programs. The unique nature of many of the remaining facilities will require a strong and responsive engineering and technology program to improve worker and public safety, and reduce costs and environmental impacts while completing the cleanup program. The technical risks and uncertainties associated with cleanup program were identified through: (1) project risk assessments, (2) programmatic external technical reviews and technology readiness assessments, and (3) direct site input. In order to address these needs, the technical risks and uncertainties were compiled and divided into the program areas of: Waste Processing, Groundwater and Soil Remediation, and Deactivation and Decommissioning ...

International Nuclear Information System (INIS)

Chorismate mutase, a branch-point enzyme in the aromatic amino acid pathway of Saccharomyces cerevisiae, and also a mutant chorismate mutase with a single amino acid substitution in the C-terminal part of the protein have been purified approximately 20-fold and 64-fold from overproducing strains, respectively. The wild-type enzyme is activated by tryptophan and subject to feedback inhibition by tyrosine, whereas the mutant enzyme does not respond to activation by tryptophan nor inhibition by tyrosine. Both enzymes are dimers consisting of two identical subunits of M_r 30,000, each one capable of binding one substrate and one activator molecule. Each subunit of the wild-type enzyme also binds one inhibitor molecule, whereas the mutant enzyme lost this ability. The enzyme reaction was observed by "1H NMR and shows a direct and irreversible conversion of chorismate to prephenate without the accumulation of any enzyme-free intermediates. The kinetic data of the wild-type chorismate mutase ...

UK PubMed Central (United Kingdom)

AbstractIndividual informed consent is a key ethical obligation for clinical studies, but empirical studies show that key requirements are often not met. Common recommendations to strengthen...Full Text Available

UK PubMed Central (United Kingdom)

Food-deprived pigeons were presented with a row of four response keys situated above a grain hopper aperture. At the start of a trial, three of four keys were randomly selected and illuminated white...Full Text Available

Science.gov (United States)

... Uninterrupted access to and use of critical infrastructure in the Arabian Gulf region are key to the successful prosecution of the Global War on Terror ...

Energy Technology Data Exchange (ETDEWEB)

In this paper, the compulsory site requirements and the site design assumptions which are being used for the present ITER plant are briefly described. A set of different parameters from the site design assumptions is also described, which was adopted as an additional exercise for cost sensitivity analysis of the ITER plant for these parameters. (orig.) 1 refs.

Science.gov (United States)

Basic cross site scripting attacks

CERN Document Server

Aerial picture of BA4 at SPS (LHC T18 building site).

International Nuclear Information System (INIS)

The performance of a convolution/superposition based treatment planning system depends on the ability of the dose calculation algorithm to accurately account for physical interactions taking place in the tissue, key components of the linac head and on the accuracy of the photon beam model. Generally the user has little or no control over the performance of the dose calculation algorithm but is responsible for the accuracy of the beam model within the constraints imposed by the system. This study explores the dosimetric impact of limitations in photon beam modeling accuracy on complex 3D clinical treatment plans. A total of 70 photon beam models was created in the Pinnacle(TM) treatment planning system. Two of the models served as references for 6 MV and 15 MV beams, while the rest were created by perturbing the reference models in order to produce specific deviations in specific regions of the calculated dose profiles (central axis and transverse). The beam models ...

International Nuclear Information System (INIS)

A single round of Edman degradation was employed to remove the NH_2-terminal valine from isolated #alpha# chains of human hemoglobin. Reconstitution of normal #beta# chains with truncated or substituted #alpha# chains was used to form truncated (des-Val"1-#alpha#1) and substituted ([[1-"1"3C]Gly"1]#alpha#1) tetrameric hemoglobin analogs. Structural homology of the analogs with untreated native hemoglobin was established by using several spectroscopic and physical methods. Functional studies indicate that the reconstituted tetrameric protein containing des-Val"1-#alpha# chains has a higher affinity for oxygen, is less influenced by chloride ions or 2,3-biphosphoglycerate, and shows lower cooperativity than native hemoglobin. These results confirm the key functional role of the #alpha#-chain NH_2 terminus in mediating cooperative oxygen binding across the dimer interface. The NH_2-terminal pK/sub 1/2/ value was determined for the ["1"3C]glycine-substituted analog to ...

International Nuclear Information System (INIS)

To demonstrate that the caustic-side solvent extraction (CSSX) process could remove cesium from Savannah River Site (SRS) high-level waste over long periods of time, an improved minicontactor (2-cm centrifugal contactor) was needed that could be operated for several days. In particular, the contractor temperature had to be controlled and contactor hydraulic performance needed to be improved. Because the process was to be continuous, provisions were made for a three-shift operation. With the improvements made and the operators trained, the CSSX process was run in a 33-stage minicontactor over a period of three days to remove cesium from an average SRS siumulant for the waste feed. The two key process goals were achieved: (1) the cesium was removed from the waste with decontamination factors greater than 40,000 and (2) the recovered cesium was concentrated by a factor of 15 in dilute nitric acid. These goals were maintained for 71 h as 1.4 L of ...

International Nuclear Information System (INIS)

The spike (S) protein of severe acute respiratory syndrome coronavirus (SARS-CoV) has two major functions: interacting with the receptor to mediate virus entry and inducing protective immunity. Coincidently, the receptor-binding domain (RBD, residues 318-510) of SAR-CoV S protein is a major antigenic site to induce neutralizing antibodies. Here, we used RBD-Fc, a fusion protein containing the RBD and human IgG1 Fc, as a model in the studies and found that a single amino acid substitution in the RBD (R441A) could abolish the immunogenicity of RBD to induce neutralizing antibodies in immunized mice and rabbits. With a panel of anti-RBD mAbs as probes, we observed that R441A substitution was able to disrupt the majority of neutralizing epitopes in the RBD, suggesting that this residue is critical for the antigenic structure responsible for inducing protective immune responses. We also demonstrated that the RBD-Fc bearing R441A mutation could not bind to soluble and ...

Energy Technology Data Exchange (ETDEWEB)

We prove that the 1984 protocol of Bennett and Brassard (BB84) for quantum key distribution is secure. We first give a key distribution protocol based on entanglement purification, which can be proven secure using methods from Lo and Chau's proof of security for a similar protocol. We then show that the security of this protocol implies the security of BB84. The entanglement purification based protocol uses Calderbank-Shor-Steane codes, and properties of these codes are used to remove the use of quantum computation from the Lo-Chau protocol. (c) 2000 The American Physical Society.

International Nuclear Information System (INIS)

This paper discusses key methods for sustaining quality engineering data, the fundamental principles that these methods are based on, and the methods for supporting the performance of nuclear power plants by the provision of quality engineering data at all times. The concept of an 'engineering data foundation', and a Configuration Management data model are developed. The concepts and methods for managing the integrity of engineering data across many different databases and document systems are developed, including the key concepts of data-positions and data-values, Master Data and Copy Data, and the concept of a 'partnership between people and technology'. (author). 7 refs., 1 tab., 2 figs.

Energy Technology Data Exchange (ETDEWEB)

This work describes the development of a synchronous key based on micro controller to the switching of three-phase power transformers, which makes possible the achievement of tests to register the inrush current, and the previous establishment of the instantaneous values of the voltage firstly applied to different phases of the energy process. This key is a value tool to the development electric power system projects and to the teaching and researching activities at the laboratory related to transitory phenomena and electric system protection.

Energy Technology Data Exchange (ETDEWEB)

This report presents geologic considerations that are pertinent to the Remedial Action Plan for Slick Rock mill tailings. Topics covered include regional geology, site geology, geologic stability, and geologic suitability.

Energy Technology Data Exchange (ETDEWEB)

This report is a summary of the environmental status of the Hanford Site in 1989. It includes descriptions of the Site and its mission, the status of compliance with environmental regulations, planning and activities to accomplish compliance, environmental protection and restoration activities, and environmental monitoring. 97 refs., 67 figs., 14 tabs.

Science.gov (United States)

although additional research is needed to corroborate such findings. Key words: Avicennia germinans; disturbance; downed wood; Everglades National Park; Hurricane Andrew;...

British Library Electronic Table of Contents (United Kingdom)

Medical Science Liaison (MSL) teams are a well-recognized function within the pharmaceutical and medical products industries. While in most organizations, MSLs have focused on the development of relationships with individual Key Opinion Leaders, progressive companies have realized the value that MSLs can also bring to Key Account Management (KAM). This article discusses the five steps that should be followed in order to successfully integrate the support of Key Accounts into an MSL function. These include understanding the business approach to KAM, identifying what MSL resources are available, developing a comprehensive strategic plan, implementing the plan, and evaluating and making any necessary adjustments. Finally, a case example outlining the experience of a small pharmaceutical compa...

Energy Technology Data Exchange (ETDEWEB)

Summary brochure of GeoPowering the West (GPW) activities, and areas of technology transfer and market transformation. It also provides current contact information for key DOE and national laboratory staff representing the GPW program.

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

UK PubMed Central (United Kingdom)

Citrate and lactose fermentation are subject to the same metabolic regulation. In both processes, pyruvate is the key intermediate. Lactococcus lactis subsp. lactis...Full Text Available

UK PubMed Central (United Kingdom)

The existence of thresholds for toxicants is a matter of debate in chemical risk assessment and regulation. Current risk assessment methods are based on the assumption that, in the absence of sufficient...Full Text Available

International Nuclear Information System (INIS)

As a condition of accession into the European Union (EU), Lithuania is committed to the closure and decommissioning of Ignalina NPP comprising two RBMK-1500 reactor units (Fig. 1). It was agreed in a special protocol to the Accession Treaty that, in return for adequate EU financial assistance, Unit 1 would be closed before 2005 and Unit 2 by the end of 2009. The first unit was duly shut down on December 31, 2004. Lithuania, which has borders with Russia (Kaliningrad territory), Poland, Latvia and Belarus, spent fifty years as part of the Soviet Union and was deeply integrated into its economy and electrical infrastructure. At the break-up of the USSR, Lithuania inherited electricity generating capacity designed to supply the north-west region including ownership of Ignalina NPP located in the north-east of the country. Ignalina NPP Unit 1 was commissioned in 1983, Unit 2 in 1987; the planned lifespan of each unit was 30 years. Construction of a third unit was started but never ...

Energy Technology Data Exchange (ETDEWEB)

This Fact Sheet provides the mission of the Savannah River Site and information on 1994 pollution prevention and recycling accomplishments.

Science.gov (United States)

Quantitative determination of Broensted acid site concentrations in calcined H-mordenite and H-ZSM-5 by means of conductometric titration and infrared spectroscopy reveals that the concentration of Broensted acid sites present is lower than would be expected on the basis of the aluminum content. This discrepancy is attributed to dealumination and dehydroxylation processes occurring during calcination. A model is proposed according to which the degree of these processes strongly depends on the concentration of vicinal aluminum T sites in the zeolite: Broensted acid sites associated with these T sites are lost, and the remaining Broensted acidity is related to the concentration of the (remaining) isolated aluminum T sites. This model quantitatively correlates the experimentally determined concentration of Broensted acid sites with the ...

Science.gov (United States)

may experience difficulty opening the Facebook page due to current HHS policy and network security that blocks access to the site. Site Map - Contact Us - Linking to USPHS.gov -...

International Nuclear Information System (INIS)

A measuring-basis encrypted quantum key distribution scheme is proposed by using twelve nonorthogonal states in a four-state system and the measuring-basis encryption technique. In this scheme, two bits of classical information can be encoded on one four-state particle and the transmitted particles can be fully used.

KoreaScience (Korea)

Full Text Available

International Nuclear Information System (INIS)

Short communication.

Science.gov (United States)

... 1970s from two different sites on the River Matadi. It is likely to be restricted to a ... ...

Science.gov (United States)

... wood, kitchen wastes, and human faeces. The ash from such waste burning shall be deposited and ...

Science.gov (United States)

Site Error There's a problem with your browser or settings. ...

CERN Document Server

A last look at the green field, in the triangular wedge of land stray radiation near the CERN accelerators.

Science.gov (United States)

PMID:21768762

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Science.gov (United States)

PMID:18387153

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

KoreaScience (Korea)

Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Data from natural runoff plots at two experimental sites in northern Iraq were used to predict soil erodibility in this semiarid region. The first site has a mean seasonal rainfall of about 400mm with the plots situated on 40% uniform slope; the soil at the site has a loam texture and belongs to the Xerorthent suborder; it has 46% of gravel by weight in its surface layer. The second site has a mean seasonal rainfall of more than 900mm with the plot situated on 17% uniform slope; the soil at the site is silty clay and belongs to the Calcixeroll suborder. At both sites, soil loss and runoff measurements were collected for two rainfall seasons. Results from both experimental sites showed that storm-to-storm variation in soil erodibility is high reflecting the importance of long term measureme...

Energy Technology Data Exchange (ETDEWEB)

This report provides an overview of the scope and status of the US Department of Energy (DOE`s) Salt Repository Project (SRP) at the time when the project was terminated by the Nuclear Waste Policy Amendments Act of 1987. The report reviews the 10-year program of siting a geologic repository for high-level nuclear waste in rock salt formations. Its purpose is to aid persons interested in the information developed during the course of this effort. Each area is briefly described and the major items of information are noted. This report, the three salt Environmental Assessments, and the Site Characterization Plan are the suggested starting points for any search of the literature and information developed by the program participants. Prior to termination, DOE was preparing to characterize three candidate sites for the first mined geologic repository for the permanent disposal of high-level nuclear waste. The ...

Energy Technology Data Exchange (ETDEWEB)

The environmental data for the NSDN are presented in the form of tables for each solar site. The solar sites are grouped into 12 zones, each of which consists of several adjacent states. The solar energy sites are in alphabetical sequence within each zone. The tables provide available meteorological data for reporting sites in the NSDN as follows: Insolation - the insolation table presents the total, diffuse, direct, maximum, and extra-terrestrial radiation for the solar site. It also shows the ratio of total extra-terrestrial radiation, as a percent. Temperature - the temperature table gives the average, daytime, nightime, maximum, minimum and inlet-water temperatures for the solar site. Additional tables are presented for some of these NSDN sites, supplying either wind or relative humidity data, or both. Wind - all of the passive and some ...

British Library Electronic Table of Contents (United Kingdom)

Purpose - This paper aims to explore the links between revenue management and business-to-business (B2B) relationships and explains how revenue management can both support and damage B2B relationships. Design/methodology/approach - A single case study method was employed to conduct qualitative research into a company and its key accounts. In-depth data were collected from three divergent sources (company revenue managers, company account managers and nine of the company's key accounts) through semi-structured interviews, observations and document studies. Findings - The research findings reveal that from the company's perspective, managers acknowledge that revenue management has positively influenced the process of identifying and analysing key account activities and conducting contractual...

British Library Electronic Table of Contents (United Kingdom)

Customer relationships, product development, data integration and demand-driven supply chains are key concepts for companies that wish to remain competitive in today?s global economy. To address this important information management issue, the present study examines how, within a demand-driven network context, an eCRM can influence the interorganizational product development process between a manufacturer and its key customers. The theoretical model, built on research related to a technology assimilation model based on Fichman?s (2000) work, was tested on data from 104 manufacturers in the wireless equipment sector. The results show that the adoption of an eCRM does not moderate the relationship between collaborative e-product development involving a manufacturer and its key customers and ...

Energy Technology Data Exchange (ETDEWEB)

The Davis GSR Landfill (GSR) is listed by the U.S. Environmental Protection Agency on the National Priorities List. Preliminary on-site sampling results have demonstrated volatile organic compounds in ground water and surface water. The contaminants present in groundwater at this site are trichloroethylene, ethylbenzene, toluene, chloromethane, tetrahydrofuran, 1,1,1-trichloroethane, and 1,2 dichloroethane. GSR represents a potential public health concern to area residents. However, information available on this site is not currently adequate to determine if a public health concern exists to these residents. At a minimum, future investigations of this site should include a characterization of the site and site contaminants, and a characterization of the hydrogeology of the area.

Energy Technology Data Exchange (ETDEWEB)

Since 1998, The Pennsylvania State University successfully managed the Consortium for Premium Carbon Products from Coal (CPCPC), which was a vehicle for industry-driven research on the promotion, development, and transfer of innovative technologies on premium carbon products from coal to the U.S. industry. The CPCPC was an initiative led by Penn State, its cocharter member West Virginia University (WVU), and the U.S. Department of Energy's (DOE) National Energy Technology Laboratory (NETL), who also provided the base funding for the program, with Penn State responsible for consortium management. CPCPC began in 1998 under DOE Cooperative Agreement No. DE-FC26-98FT40350. This agreement ended November 2004 but the CPCPC activity continued under cooperative agreement No. DE-FC26-03NT41874, which started October 1, 2003 and ended December 31, 2010. The objective of the second agreement was to continue the successful operation of the CPCPC. The CPCPC enjoyed tremendous success with ...

International Nuclear Information System (INIS)

Immunoassays are versatile analytical techniques that had a leading role in various clinical applications, during the last four decades. The studies carried out by Rosalyn Yalow, Solomon Berson and Roger Ekins in the 1960s gave a breakthrough in the development of this novel analytical method. Sensitivity up to femtomolar concentrations, high specificity and universal application to different classes of molecular species made immunoassay a very useful tool in analytical investigation. The expertise acquired by immunochemists in producing antibodies against any antigen and the ability of radiochemists in labeling the antigens with "1"2"5I without affecting the active site are the two main factors responsible for the above development. There are concerns about the safety and health of humans due to the high-level contamination of environment by pesticides, industrial compounds and metals, anabolic steroids in milk and meat products, and presence of mycotoxins in food ...

International Nuclear Information System (INIS)

Full text: The site selection process for a near surface repository dedicated for the radioactive waste resulted from the Cernavoda NPP operation and decommissioning started early in 90's. Each site selection stage included the collection of data from specific field and laboratory works as well as the appropriate safety performance evaluation. In order to assess/confirm the performance of the natural barrier of the Saligny site, the radionuclide concentration in the disposal system compartments has been evaluated, as complementary safety indicator of repository. The siting process was made in accordance with national and international regulations and standards and using a conceptual design similar to those used at L'Aube (France), ElCabril (Spain) or Mohovce (Slovak Republic). ANDRAD, the Romanian waste management organization that has continued the siting process in the last three ...

Energy Technology Data Exchange (ETDEWEB)

The UK government's economy-wide 60% carbon dioxide reduction target by 2050 requires a paradigm shift in the whole energy system. Numerous analytical studies have concluded that the power sector is a critical contributor to a low carbon energy system, and electricity generation has dominated the policy discussion on UK decarbonisation scenarios. However, range of technical, social and market challenges, combined with alternate market investment strategies mean that large scale deployment of key classes of low carbon electricity technologies is fraught with uncertainty. The UK MARKAL energy systems model has been used to investigate these long-term uncertainties in key electricity generation options. A range of power sector specific parametric sensitivities have been performed under a 'what-if' framework to provide a systematic exploration of least-cost energy system configurations under a broad, integrated set of ...

UK PubMed Central (United Kingdom)

While it has been established that microRNAs (miRNAs) play key roles throughout development and are dysregulated in many human pathologies, the specific processes and pathways regulated by individual...Full Text Available

Science.gov (United States)

The astronomical number of letters handled by the Post Office makes automatic sorting technology essential. Key roles are played by the postcode system and an ink-jet printer that has been developed to use phosphorescent inks.

UK PubMed Central (United Kingdom)

SummaryIn vivo tumor cell migration through integrin-dependent pathways is key to the metastatic behavior of malignant cells. Using quantitative in vivo...Full Text Available

UK PubMed Central (United Kingdom)

By analysis of crossovers in key recombinant families and by homozygosity analysis of inbred families, the Friedreich ataxia (FRDA) locus was localized in a 300-kb interval between the X104 gene and...Full Text Available

UK PubMed Central (United Kingdom)

This paper describes the deliverables framework developed by Vanderbilt University Medical Center (VUMC) in its IAIMS planning process. The key deliverables include: visions for the future; mission,...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundHyaluronic acid capsule plays a key role in Streptococcus pyogenes virulence. Circulation of mucoid or highly encapsulated strains has been related to...Full Text Available

Wastenet

...A directory of University social media accounts, including Facebook, Twitter and YouTube facebook, twitter, blog Social media - Social media, The ... Key: Facebook, Twitter, YouTube, Blog, LinkedIn, Flickr Missed you out? If you'd like to be included on this ...

UK PubMed Central (United Kingdom)

BackgroundMicrovascular injury plays a key role in normal tissue radiation responses. Statins, in addition to their lipid-lowering effects, have vasculoprotective...Full Text Available

UK PubMed Central (United Kingdom)

Receptor activator of NF-kB ligand (RANKL) and osteoprotegerin (OPG) play key roles in the pathogenesis of glucocorticoid-induced osteoporosis (GIO). The aim of our study was to determine whether the...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

French scientists think they have discovered one of the key steps in the methanol-to-gasoline reaction pathway and their British counterparts have learned a new way of converting methanol into acetic acid without carbon monoxide.

UK PubMed Central (United Kingdom)

BackgroundRifampin is a key drug in antituberculosis chemotherapy because it rapidly kills the majority of bacilli in tuberculosis lesions, prevents relapse and thus enables 6-month...Full Text Available

UK PubMed Central (United Kingdom)

A structurally conserved element, the trigger loop, has been suggested to play a key role in substrate selection and catalysis of RNA polymerase II (pol II) transcription elongation. Recently resolved...Full Text Available

UK PubMed Central (United Kingdom)

Four-dimensional (4D) radiotherapy is the explicit inclusion of the temporal changes in anatomy during the imaging, planning, and delivery of radiotherapy. One key component of 4D radiotherapy planning...Full Text Available

UK PubMed Central (United Kingdom)

Stem cells are expected to play a key role in the development and maintenance of organisms, and hold great therapeutic promises. However, a number of questions must be answered to achieve an...Full Text Available

UK PubMed Central (United Kingdom)

Mycolic acids are key cell wall components for the survival, pathogenicity, and antibiotic resistance of the human tubercle bacillus. Although it was thought that Mycobacterium tuberculosis...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundDysregulation of the insulin-like growth factor (IGF) system, a common consequence of adiposity-induced insulin resistance, may be a key underlying mechanism...Full Text Available

UK PubMed Central (United Kingdom)

Objective: To highlight the key differences in history, examination, and management of pyoderma gangrenosum and necrotizing fasciitis and to outline the importance of distinguishing these...Full Text Available

UK PubMed Central (United Kingdom)

AbstractIntrathymic expression of tissue-restricted antigens (TRAs) has been viewed as the key element in the induction of central tolerance and recently, a central role for the autoimmune...Full Text Available

UK PubMed Central (United Kingdom)

Background Little is known about how migrants adapt to first-world public health systems. In Norway, patients are assigned a registered general practitioner (RGP) to provide basic care...Full Text Available

UK PubMed Central (United Kingdom)

Background/Objective:To determine the utility of certain instruments to assess sexuality and fertility after SCI, an expert panel identified key areas to study and evaluated...Full Text Available

UK PubMed Central (United Kingdom)

Despite the availability of dozens of animal genome sequences, two key questions remain unanswered: First, what fraction of any species' genome confers biological function, and second, are apparent...Full Text Available

UK PubMed Central (United Kingdom)

Blunt chest-wall trauma is common; however, resultant tricuspid valve rupture is rare and can be subtle in its presentation. Transthoracic echocardiography plays a key role in diagnosis.Herein,...Full Text Available

UK PubMed Central (United Kingdom)

Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is considered a key process driving tumor cell invasiveness and metastasis....Full Text Available

Wastenet

KOREA-JAPAN NUCLEAR WEAPON FREE ZONE (KJNWFZ) CONCEPT PAPER ...A Korea-Japan2 Nuclear Weapon Free Zone (hereafter KJNWFZ) is a new concept.Once realized, ...Finally, we outline the key elements of the Korea-Japan NWFZ proposed in this paper, noting

UK PubMed Central (United Kingdom)

Insulin resistance in skeletal muscle is a key phenotype associated with type 2 diabetes (T2D) for which the molecular mediators remain unclear. We therefore conducted an expression analysis of human...Full Text Available

UK PubMed Central (United Kingdom)

The spliced alignment of expressed sequence data to genomic sequence has proven a key tool in the comprehensive annotation of genes in eukaryotic genomes. A novel algorithm was developed to assemble...Full Text Available

UK PubMed Central (United Kingdom)

Background:The cardiac sodium–calcium exchanger (NCX1) is a key sarcolemmal protein for the maintenance of calcium homeostasis in the heart. Since heart failure...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundDue to the high morbidity and mortality of fulminant hepatitis, early diagnosis followed by early effective treatment is the key for prognosis improvement. So far, little...Full Text Available

UK PubMed Central (United Kingdom)

Rapid place encoding by hippocampal neurons, as reflected by place-related firing, has been intensely studied, whereas the substrates that translate hippocampal place codes into behavior have received...Full Text Available

UK PubMed Central (United Kingdom)

Extended-spectrum beta-lactamases (ESBL) constitute a key antibiotic-resistance mechanism affecting Gram-negative bacteria, and also an excellent model for studying evolution in real time. A shift in...Full Text Available

UK PubMed Central (United Kingdom)

Chemoprevention strategies to prevent the development of lung cancer in at-risk individuals are a key component in disease management. In addition to being highly effective, an ideal chemopreventive...Full Text Available

Science.gov (United States)

... Steady State 16.0-28.0 5.05 to 5.36 0 Key switch turned on. ... version may have been the better choice since the acousto-optic modulator also ...

UK PubMed Central (United Kingdom)

The mitogen-activated protein kinase/extracellular regulated kinase (MAPK/ERK) pathway plays a key role in mediating estrogen actions in the brain and neuronal sensitization during inflammation....Full Text Available

UK PubMed Central (United Kingdom)

Under anaerobic conditions, several species of green algae perform a light-dependent hydrogen production catalyzed by a special group of [FeFe] hydrogenases termed HydA. Although highly interesting...Full Text Available

UK PubMed Central (United Kingdom)

We review the application of C. elegans as a model system to understand key aspects of stem cell biology. The only bona fide stem cells in C. elegans...Full Text Available

CERN Document Server

To establish secure (point-to-point and/or broadcast) communication channels among the nodes of a wireless sensor network is a fundamental task. To this end, a plethora of (socalled) key pre-distribution schemes have been proposed in the past. All these schemes, however, rely on shared secret(s), which are assumed to be somehow pre-loaded onto the sensor nodes. In this paper, we propose a novel method for secure initialization of sensor nodes based on a visual out-of-band channel. Using the proposed method, the administrator of a sensor network can distribute keys onto the sensor nodes, necessary to bootstrap key pre-distribution. Our secure initialization method requires only a little extra cost, is efficient and scalable with respect to the number of sensor nodes. Moreover, based on a usability study that we conducted, the method turns out to be quite user-friendly and easy to use by naive human users.

UK PubMed Central (United Kingdom)

The aim of the overview is to give a perspective of global biobank development is given in a view of positioning biobanking as a key resource for healthcare to identify new potential markers that can...Full Text Available

UK PubMed Central (United Kingdom)

Background and aims: Serotonin (5-hydroxtryptamine, 5-HT) is an important factor in gut function, playing key roles in intestinal peristalsis and secretion, and in sensory...Full Text Available

UK PubMed Central (United Kingdom)

The cofactor nicotinamide adenine dinucleotide (NAD+) has emerged as a key regulator of metabolism, stress resistance and longevity. Apart from its role as ...Full Text Available

UK PubMed Central (United Kingdom)

AMP-activated protein kinase (AMPK) is a key regulator of energy metabolism; its activity is regulated by a plethora of physiological conditions, exercises and many anti-diabetic drugs. Recent...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundStable transgenesis is an undeniable key to understanding any genetic system. Retrovirus-based insertional strategies, which feature several technical challenges when they...Full Text Available

UK PubMed Central (United Kingdom)

The vanilloid receptor-1 (VR1, or transient receptor potential vanilloid-1 receptor, TRPV1) is activated by capsaicin, the key ingredient of hot peppers. TRPV1 was originally described on sensory neurons...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

As part of the demonstration testing of the Purge Water Management System (PWMS) technology at the Savannah River Site (SRS), four wells were equipped with PWMS units in 1997 and a series of sampling events were conducted at each during 1997-1998. Three of the wells were located in A/M Area while the fourth was located at the Old Radioactive Waste Burial Ground in the General Separations Area.The PWMS is a ''closed-loop'', non-contact, system used to collect and return purge water to the originating aquifer after a sampling event without having significantly altered the water quality. One of the primary concerns as to its applicability at SRS, and elsewhere, is whether the PWMS might resample groundwater that is returned to the aquifer during the previous sampling event. The purpose of the present investigation was to compare groundwater chemical analysis data collected at the four test wells using the PWMS vs. historical data ...

Science.gov (United States)

Two avowable quantum communication schemes are proposed. One is an avowable teleportation protocol based on the quantum cryptography. In this protocol one teleports a set of one-particle states based on the availability of an honest arbitrator, the keys and the Einstein Podolsky Rosen pairs shared by the communication parties and the arbitrator. The key point is that the fact of the teleportation can neither be disavowed by the sender nor be denied by the receiver. Another is an avowable quantum secure direct communication scheme. A one-way Hash function chosen by the communication parties helps the receiver to validate the truth of the information and to avoid disavowing for the sender.

Energy Technology Data Exchange (ETDEWEB)

Trapped ions are a near ideal system to study quantum information processing due to the high degree of control over the ion's external confinement and internal degrees of freedom. We demonstrate the key steps necessary for trapped ion quantum computing and focus on phonon-mediated entangling gates. We highlight several key algorithms implemented over the last decade with these gates and give a detailed description of Grover's quantum database search implemented with two trapped ion qubits.

Energy Technology Data Exchange (ETDEWEB)

With increasing liberalization of the energy sector, German suppliers of line-transmitted energy find themselves in an utterly changed sales environment, forcing companies and utilities to elaborate for the first time management policies and strategies that will ensure loyalty of their present customers, and help to solicit new customers. The article here explains some major terms and instruments used in designing key-account management strategies, as well as general procedures for suitability assessment. (orig/CB)

Energy Technology Data Exchange (ETDEWEB)

A complete guide to 7000 key decision makers and 2800 organizations actively involved in energy today, the 1983 Directory updates the changes in state and Congressional energy offices that resulted from the 1982 elections, the reshuffling at DOE, the shifts of jurisdiction at the Department of the Interior, and the increasing role of the private sector in funding energy research and development. New features include the addition of nearly 100 major venture-capital firms and key public-affairs contacts. The Directory also features an Annual Energy Review highlighting development that will have international effects in the coming year.

British Library Electronic Table of Contents (United Kingdom)

This article presents a linear-analytical case study on the development of ICT within the educational systems of Chile and South Korea. Through a comprehensive meta-data analysis and bibliographic review, we collected information on both educational systems and their ICT adoption policies. Key differences necessary to understand how both countries have developed their educational systems by integrating ICT were analyzed, including the educational system structure, the organization of state entities responsible for educational ICT, cultural characteristics, the creation of policies regarding ICT in education, and the effectiveness of such policies for the expansion of infrastructure and the ICT curriculum integration. We analyze these key differences in order to understand two cases of ICT ...

UK PubMed Central (United Kingdom)

BackgroundWe aimed to compare visual and refractive outcome following phacoemulsification and intraocular lens implant (IOL) and combined one-site phacotrabeculectomy.MethodWe...Full Text Available

Science.gov (United States)

Our research in the general area of acid catalysis involves the characterization of solid acidity and the corresponding assessment of catalytic performance of acidic materials. Acid characterization studies are required to provide essential information about the type of acid site (i.e., Lewis versus Bronsted), the strength of the sites, and the mobility of molecules adsorbed on the acid sites. An accurate measure of acid strength is given by the heat of adsorption of a basic probe molecule on the acid site. A thermodynamic representation of the mobility of adsorbed species on these sites is given by the entropy of adsorption. Important techniques used in these acid site characterization studies include microcalorimetry, thermogravimetric measurements, temperature programmed desorption, infrared spectroscopy and solid state nuclear magnetic resonance. The ...

Energy Technology Data Exchange (ETDEWEB)

Experiments were carried out to learn methanol sorption characteristics of heat-treated coal. When Taiheiyo coal is heat-treated at 125{degree}C, performed with a first methanol adsorption at 25{degree}C, and then desorption at 25{degree}C, a site with strong interaction with methanol and a site with relatively weak interaction are generated in test samples. A small amount of methanol remains in both sites. Then, when the methanol is desorbed at as low temperature as 70{degree}C, the methanol in the site with strong interaction remains as it has existed therein, but the methanol in the site with relatively weak interaction desorbs partially, hence the adsorption amount in a second adsorption at 25{degree}C increases. However, when desorption is performed at as high temperature as 125{degree}C, the methanol in the site with strong interaction also desorbs, ...

Energy Technology Data Exchange (ETDEWEB)

This report documents site remediation at ORNL, including ORNL site characterization technologies, waste management and robotics and automation of the laboratory for waste processing and analysis.

UK PubMed Central (United Kingdom)

Chromosomal common fragile sites (CFSs) are genetically unstable regions of the genome that are induced by conditions that impair DNA replication. In this report, we show that treatment with the DNA...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

UK Nirex has announced four sites which it wishes to assess for the disposal of low-level and short-lived intermediate-level radioactive wastes. There is local opposition at all four of the potential sites. (U.K.).

UK PubMed Central (United Kingdom)

Photobilirubin II, a stereoisomer of bilirubin, binds to human serum albumin at a single binding site (K = 2.2 x 10(6)M-1), presumably the high-affinity bilirubin-binding site. Binding in the secondary...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Brine from active oil wells seeped through the soil of a forested site in north-western Pennsylvania and killed all vegetation in its path, leaving the affected area unproductive and unsightly. After the brine source was eliminated, herbaceous plants, shrubs and forest tree seedlings became established and developed rapidly. Establishment began in the first year and by Year 4 the site had developed into a healthy young forest. Results show that Allegheny hardwood forest sites damaged by brine water will rapidly revegetate once the brine water discharge is stopped if there is a seed supply and if the area is fenced to exclude deer. 3 figs., 12 refs.

Science.gov (United States)

Surface temperature is measured with an infrared thermometer. Measuring Surface Temperature. Nine sample points are selected with a site of uniform land ...

Energy Technology Data Exchange (ETDEWEB)

In accordance with the requirements of Section 113 (b) (3) of the Nuclear Waste Policy Act of 1982, as amended (NWPA), the US Department of Energy (DOE) has prepared this report on the progress of site characterization activities at Yucca Mountain, Nevada, for the period October 1, 1990, through March 31, 1991. This report is the fourth in a series of reports that are issued at intervals of approximately six months during site characterization. The report covers a number of initiatives to improve the effectiveness of the site characterization program, and covers continued efforts related to preparatory activities, Study Plans, and performance assessment.

Energy Technology Data Exchange (ETDEWEB)

The Savannah River Site has successfully used robots, teleoperators, and remote video to reduce exposure to ionizing radiation, improve worker safety, and improve the quality of operations. Previous reports have described the use of mobile teleoperators in coping with a high level liquid waste spill, the removal of highly contaminated equipment, and the inspection of nuclear reactor vessels. This report will cover recent applications at the Savannah River, as well as systems which SRS has delivered to other DOE site customers.

Science.gov (United States)

Using low-temperature adsorbed dihydrogen and carbon monoxide as molecular probes, the dehydroxylation of the hydrogen forms of the zeolites Y, and ZSM-5 has been studied. The high stability of the high-silica zeolites to dealumination and their difference from faujasites has been established as being due not only to the strength of their Broensted acid sites but also to the nature of their Lewis acid sites. The chemical properties of the Lewis acid sites and their possible role in catalytic reactions are discussed.

Indian Institute of Science Theses & Dissertations (India)

Full Text Available

International Nuclear Information System (INIS)

A three dimensional sea-land breeze model has been employed for the study on the inland penetration of sea breeze around Wolsung NPP site. In this study, the sea breeze simulation was carried out under the weak northwesterly geostrophic wind (3.2 m/s, 339 .deg.) at 850 hPa in Spring. The results showed that sea breezes developed near Wolsung site penetrated into about 20 km inland under the weak northwesterly geostrophic wind in Spring. This result agreed with observation data around Wolsung site on May 1996.

Energy Technology Data Exchange (ETDEWEB)

New technological advances make it possible to perform on site gas-in-oil analysis quickly and efficiently. Gas-in-oil analysis is crucial in assessing the status of oil-filled electrical equipment. The new technique is used for extracting and measuring gases dissolved in electrical insulating oil. On-site sampling requires the use of a specially designed 100 ml capacity syringe. Extraction of the dissolved gases is made with a precise ratio of oil to air. A comparison was made between the analysis of the on-site and the laboratory techniques. Results showed that the detection limits of the on-site technique were comparable to those obtained by laboratory methods.

International Nuclear Information System (INIS)

... e Biologia Molecular (SBBq), Sao Paulo, SP (Brazil) 217 p. APPLIED LIFE

Science.gov (United States)

Aluminum electrolytic capacitors have a long history of reliable operation in unattended field sites. However, their use in the expected space applications ...

International Nuclear Information System (INIS)

We apply our work on fracture- and matrix-dominated flow to develop a conceptual model of hydrological flow processes in the unsaturated zone at Yucca Mountain. The possibility of fracture-dominated flow is discussed, and various deductions are made on its impact on natural and total system performance, site characterization activities, and site suitability determination.

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In rat adipocyte membranes, both beta-adrenergic agonists and beta-adrenergic antagonists competed with (--)(/sup 3/H)dihydroalprenolol for high affinity (KD 2-4 nM) and low capacity binding sites. The antagonists but not the agonists competed with (--)(/sup 3/H)dihydroalprenolol for lower affinity and higher capacity sites. The present studies were performed in order to characterize the adipocyte beta-adrenergic receptor and distinguish it from low affinity, higher capacity sites which were heat-labile and not stereoselective. When isoproterenol was used to define the nonspecific binding, saturation studies showed a single binding site with a capacity of approximately 100 fmol/mg membrane protein (corresponding to approximately 50,000 sites/adipocyte). Binding was saturated by 10 nM (--)(/sup 3/H)dihydroalprenolol. Approximate KD's of 204 nM were observed. Kinetic analysis ...

UK PubMed Central (United Kingdom)

Human serum albumin (HSA) has two primary binding sites for drug molecules. These sites selectively bind different dansylated amino acid compounds, which—due to their intrinsic fluorescence—have...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The purpose of this interim remedial measures (IRM) proposed plan is to present and solicit public comments on the IRM planned for the 200-ZP-1 Operable Unit at the Hanford Site in Washington state. The 200-ZP-1 is one of two operable units that envelop the groundwater beneath the 200 West Area of the Hanford Site.

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Nomographs have been developed to simplify site performance estimates for various types of gas turbine engines used for industrial applications. The nomographs can provide valuable data for engineers to use for an initial appraisal of projects where gas turbines are to be considered. General guidelines for the selection of gas turbines are also discussed. In particular, site conditions that influence the performance of gas turbines are described.

Science.gov (United States)

This report has been prepared in conjunction with an environmental baseline study for a commercial coal conversion facility being conducted by Ashland Synthetic Fuels, Inc. (ASFI) and Airco Energy Company (AECO). This report represents a cultural resource assessment for the proposed plant site and two potential solid waste disposal areas. This assessment presents data collected by Dames and Moore during a recent archaeological reconnaissance of the unsurveyed southeastern portion of the proposed plant site and two potential solid waste disposal areas. Also, results of two previous surveys on the northern and southwestern portion of the plant site for American Smelting and Refining Company (ASARCO) and Kentucky Utilities are included. The Dames and Moore survey of the southeastern portion of the plant site identified one archaeological site, three standing structures and one historic ...

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Surveillance and maintenance (S M) of 75 sites were conductd by the Remedial Action Section for the Environmental Restoration Program for surplus facilities and sites contaminated with radioactive materials and/or hazardous chemicals. S M activities on these sites were conducted from the end of their operating life until final facility disposal or site stabilization. The objectives of the Waste Area Grouping S M Program are met by maintaining a program of routine S M as well as by implementing interim corrective maintenance when deemed necessary as a result of site surveillance. This report briefly presents this program's activities and includes tables indicating tank levels and dry well data for FY 1991.

Energy Technology Data Exchange (ETDEWEB)

This remedial investigation (RI)/feasibility study (FS) supports the selection of remedial actions for the David Witherspoon, Inc. 901 Maryville Pike Site in Knoxville, Tennessee. Operations at the site, used as a recycling center, have resulted in past, present, and potential future releases of hazardous substances in to the environment. This Site is a Tennessee Superfund site. A phased approach was planned to (1) gather existing data from previous investigations managed by the Tenn. Dept. of Environment and Conservation; (2) perform a preliminary RI, including risk assessments, and an FS with existing data to identify areas where remedial action may be necessary; (3) gather additional field data to adequately define the nature and extent of risk-based contaminants that present identifiable threats to human and/or ecological receptors; and (4) develop remedial action alternatives to reduce risks to ...

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The ammoxidation of propane over VSb{sub y}O{sub x} catalysts (y=1, 2, 5) was investigated with respect to the role of different oxygen species in the selective and non selective reaction steps using transient experiments in the Temporal Analysis of Products (TAP) reactor. Only lattice oxygen is involved in the oxidation reactions. Using isotopic labelled oxygen it is shown that two different active sites exist on the surface. On site A, which can be reoxidized faster by gas phase oxygen compared to site B, mainly CO is formed. On site B CO{sub 2} and acrolein as well as NO and N{sub 2}O in the presence of ammonia in the feed gas are formed and reoxidation mainly occurs with bulk lattice oxygen. (orig.)

British Library Electronic Table of Contents (United Kingdom)

Methylation of the DNA bases in the Watson-Crick GC and AT base pairs by the methyldiazonium ion was investigated employing density functional and second order Moller-Plesset (MP2) perturbation theories. Methylation at the N3, N7 and O6 sites of guanine, N1, N3 and N7 sites of adenine, O2 and N3 sites of cytosine and the O2 and O4 sites of thymine were considered. The computed reactivities for methylation follow the order N7(guanine)>N3(adenine)>O6(guanine) which is in agreement with experiment. The base pairing in DNA is found to play a significant role with regard to reactivities of the different sites.

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Guidelines for uranium residual radioactive material in soil were derived for the B&T Metals Company site in Columbus, Ohio. This site has been identified for remedial action under the US Department of Energy`s (DOE`s) Formerly Utilized Sites Remedial Action Program (FUSRAP). Single-nuclide and total-uranium guidelines were derived on the basis of the requirement that following remedial action, the 50-year committed effective dose equivalent to a hypothetical individual living or working in the immediate vicinity of the site should not exceed a dose constraint of 30 mrem/yr for the current use and likely future use scenarios or a dose limit of 100 n-mrem/yr for less likely future use scenarios. The DOE residual radioactive material guideline computer code, RESRAD, was used in this evaluation. RESRAD implements the methodology described in the DOE manual for establishing residual radioactive material ...

Energy Technology Data Exchange (ETDEWEB)

The Baird and McGuire site is a former chemical manufacturing facility in northwest Holbrook, Massachusetts, approximately 14 miles south of Boston. From 1912 to 1983 the company operated a chemical manufacturing and batching facility on the property. Manufactured products included herbicides, pesticides, disinfectants, soaps, floor waxes and solvents. Waste disposal methods at the site included direct discharge into the soil, nearby brook and wetlands, and a former gravel pit (now covered) in the eastern portion of the site. EPA conducted a removal action at the site in 1983 after a waste lagoon overflowed spreading contaminants into the Cochato River. The company ceased operating shortly thereafter. A second removal action was conducted in 1985, following the discovery of dioxin in site soils. EPA also conducted an Initial Remedial Measure at the site from ...

Energy Technology Data Exchange (ETDEWEB)

Consideration of the technical feasibility of Yucca Mountain in Nevada as the site for a high-level nuclear waste repository has led to an intense debate regarding the economic, social, and political impacts of the repository. Impediments to the siting process mean that the nuclear waste problem is being resolved by adhering to the status quo, in which nuclear waste is stored at scattered sites near major population centers. To assess the merits of alternative siting strategies--including both the permanent repository and the status quo- we consider the variables that would be included in a model designed to select (1) the optimal number of disposal facilities, (2) the types of facilities (e.g., permanent repository or monitored retrievable facility), and (3) the geographic location of storage sites. The objective function in the model is an all-inclusive measure of social cost. The ...

Energy Technology Data Exchange (ETDEWEB)

Although the subtrate binding properties of adenylate kinase (AK) have been studied extensively by various biochemical and biophysical techniques, it remains controversial whether uncomplexed adenosine 5'-triphosphate (ATP) binds to the adenosine 5'-monophosphate (AMP) site of AK. The authors present two sets of experiments which argue against binding of ATP to the AMP site. (a) /sup 31/P nuclear magnetic resonance titration of ATP with AK indicated a 1:1 stoichiometry on the basis of changes in coupling constants and line widths. This ruled out binding of ATP to both sites. (b) ATP and MgATP were found to behave similarly by protecting AK from spontaneous inactivation while AMP showed only a small degree of protection. Such inactivation could also be protected or reversed by dithioerythritol and is most likely due to oxidation of sulfhydryl groups, one of which (cysteine-25) is located near the MgATP ...

Energy Technology Data Exchange (ETDEWEB)

The Maybell uranium mill tailings site is 25 miles (mi) (40 kilometers [km]) west of the town of Craig, Colorado, in Moffat County, in the northwestern part of the state. The unincorporated town of Maybell is 5 road mi (8 km) southwest of the site. The site is 2.5 mi (4 km) northeast of the Yampa River on relatively flat terrain broken by low, flat-topped mesas. U.S. Highway 40 runs east-west 2 mi (3.2 km) south of the site. The designated site covers approximately 110 acres (ac) (45 hectares [ha]) and consists of a concave-shaped tailings pile and rubble from the demolition of the mill buildings buried in the former mill area. The site is situated between Johnson Wash to the east and Rob Pit Mine to the west. Numerous reclaimed and unreclaimed mines are in the immediate vicinity. Aerial photographs (included at the end of this executive summary) show evidence ...

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A transplant experiment was conducted to determine whether standard metabolic rate (SMR) of a freshwater shrimp (Palaeomonetes paludosus) would be affected by exposure to trace element-enriched coal combustion waste (coal ash). Shrimp were transplanted into replicate cages in a coal ash-polluted site and a reference site for 8 months. The coal ash-polluted site was characterized by elevated sediment concentrations of As, Cd, Cr, Cu, Ni, Pb and Se compared to sediments in the reference site. After 8 months in the study sites, shrimp in the polluted site appeared to have accumulated As, Cd and Se from the habitat, but there were on differences in survival between the study sites. However, mean SMR of shrimp (measured as O{sub 2} consumption at rest) held in the polluted site was 51% higher than mean SMR of shrimp held in ...

Science.gov (United States)

A ground-breaking study was recently completed as part of the Seabrook Level 2 PRA update. This study updates the post-core damage phenomena to be consistent with the most recent information and includes accident management activities that should be modeled in the Level 2 PRA. Overall, the result is a Level 2 PRA that fully meets the requirements of the ASME PRA Standard with respect to modeling accident management in the LERF assessment and NRC requirements in Regulatory Guide 1.174 for considering late containment failures. This technical paper deals only with the incorporation of operator actions into the Level 2 PRA based on a comprehensive study of the Seabrook Station accident response procedures and guidance. The paper describes the process used to identify the key operator actions that can influence the Level 2 PRA results and the development of success criteria for these key operator actions. This addresses a key ...

International Nuclear Information System (INIS)

This report presented some quick facts about oil and gas pipelines in Turkey and presented opportunities for trade. The key players and customers in the oil and gas sector were described along with an export check list. Turkey is looking into becoming an energy bridge between oil and gas producing countries in the Middle East, Central Asia and Europe. The oil and gas sectors are dominated by the Turkish Petroleum Corporation, a public enterprise dealing with exploration and production, and the State Pipeline Corporation which deals with energy transmission. They are also the key buyers of oil and gas equipment in Turkey. There are several pipelines connecting countries bordering the Caspian Sea. Opportunities exist in the areas of engineering consulting as well as contracting services for oil and gas pipeline transmission and distribution. Other opportunities lie in the area of pipeline construction, rehabilitation, materials, equipment, ...

International Nuclear Information System (INIS)

Quantum key distribution (QKD) can, in principle, provide unconditional security based on the fundamental laws of physics. Unfortunately, a practical QKD system may contain overlooked imperfections and may thus violate some of the assumptions in the security proofs of QKD. It is important to explore these assumptions. One key assumption is that the sender (Alice) can prepare the required quantum states without errors. However, such an assumption may be violated in a practical QKD system. In this paper, we perform a proof-of-principle experiment to demonstrate a technically feasible 'intercept- and-resend' attack that exploits such a security loophole in a commercial 'plug and play' QKD system. The resulting quantum bit error rate is 19.7%, which is substantially lower than the well-known 25% error rate for an intercept-and-resend attack in BB84. The attack we utilize is the phase-remapping attack (Fung et al 2007 Phys. Rev. A 75 32314) proposed ...

Energy Technology Data Exchange (ETDEWEB)

A method to control charge transfer reaction in DNA using hybrid nanometer-sized TiO{sub 2} nanoparticles was developed. In this system extended charge separation reflects the sequence of DNA and was measured using metallic silver deposition or by photocurrent response. Light-induced extended charge separation in these systems was found to be dependent on the DNA-bridge length and sequence. The yield of photocatalytic deposition of silver was studied in systems having GG accepting sites imbedded in AT runs at varying distances from the TiO{sub 2} nanoparticle surface. Weak distance dependence of charge separation indicative of a hole hopping through mediating adenine (A) sites was found. The quantum yield of silver deposition in the system having a GG accepting site placed 8.5 {angstrom} from the nanoparticle surface was found to be {Phi} = 0.70 (70%) and {Phi} = 0.56 (56%) for (A){sub n} and (AT){sub n/2} bridge, ...

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Full text: Recent geoarchaeological research in the Erzurum district, north-eastern Anatolia, has revealed an abundance of obsidian at numerous neolithic and Bronze Age sites. Geochemical characterisation using neutron activation analysis indicates that the obsidian was obtained from several sources that are chemically distinct from the major sources already known from Central Anatolia an the Lake Van area. Multiple sources are represented in the samples collected from at least two of the sites, namely the sites of Sos and Pulur. The primary source of some of the obsidian utilised at the site of Sos has been located in the volcanic sequence outcropping tot he north-west of Pasinler. Field survey however has shown that the alluvial deposits along the main rivers and some of their tributaries were the main sources of the obsidian utilised at the sites near Erzurum. Trade or exchange ...

Energy Technology Data Exchange (ETDEWEB)

The production of de-inked tailings in Quebec has significantly increased during the last decade. From less than 100,000 wet tons in 1990, the production of de-inked tailings reached 500,000 wet tons in 1995, and 510,000 wet tons in 1999. The geotechnical, hydraulic, and physico-chemical properties of de-inked tailings are favorable for its use as soil cover for the prevention of acid mine drainage at mining sites. In this presentation, the authors discussed the three-year monitoring of the behaviour of a membrane covering an old mining site with the potential to produce acid mine drainage. The site is located at the Clinton Mine, near Woburn, Quebec. The mine shaft was filled with the tailings and waste rock scattered around the site and covered with a protective membrane which included de-inked tailings. The profile of the membrane was discussed, as well as construction details. The results confirmed ...

British Library Electronic Table of Contents (United Kingdom)

Cyst nematodes are troublesome parasites that live on, and destroy, a range of important host vegetable plants. Damage caused by the potato cyst nematode has now been reported in over 50 countries. One approach to eliminating the problem is to stimulate early hatching of the nematodes, but key hatching stimuli are not naturally available in sufficient quantities to do so. Here, we report the first chemical synthesis of solanoeclepin A, the key hatch-stimulating substance for potato cyst nematode. The crucial steps in our synthesis are an intramolecular cyclization reaction for construction of the highly strained tricyclo[5.2.1.01,6]decane skeleton (DEF ring system) and an intramolecular Diels???Alder reaction of a furan derivative for the synthesis of the ABC carbon framework. The present ...

British Library Electronic Table of Contents (United Kingdom)

Floating production storage and offloading (FPSO) vessels offer a cost-effective field development solution, especially in deepwater areas lacking an adequate pipeline network. Most FPSOs are permanently moored, i.e. the complete system is designed to withstand any kind of extreme environment at the field location. FPSOs that can be quickly disconnected from their moorings and risers have also been designed and deployed. The key feature of this type of disconnectable FPSO is that it can be disconnect and so avoid dangerous environmental conditions such as icebergs, hurricanes in the Gulf of Mexico and typhoons in the South China Sea. In this paper, the concept of disconnectable FPSOs for deepwater field development is presented. Key technologies and their engineering analyses are highlight...

British Library Electronic Table of Contents (United Kingdom)

Remote sensing is the most practical method available to managers of fire-prone forests for quantifying and mapping fire impacts. Differenced Normalised Burn Ratio (?NBR) is among the most widely used spectral indices for the mapping of burn severity but is difficult to interpret in terms of fire-related changes in key biophysical attributes and processes. We propose to quantify burn severity as a change in the leaf area index (?LAI) of a stand. LAI is a key biophysical attribute of forests, and is central to understanding their water and carbon cycles. Previous studies have suggested that changes in canopy LAI may be a major contributor to ?NBR and to the composite burn index (CBI) that is frequently used in combination with the NBR to assess burn severity on the ground. We applied remote...

Energy Technology Data Exchange (ETDEWEB)

The document provides: An overview of CCS technology including what plant equipment is novel and what is currently in use within the CCS or other industries; An in depth guide to carbon dioxide to broaden the readers understanding of the material and its health and safety issues; Key design features of plant and pipelines for carbon dioxide service including experience gained from the industrial gases sector; and Key operational information for plant and pipelines for carbon dioxide service including experience gained from the industrial gases sector to ensure that your operating practices take into account the latest operational experiences from carbon dioxide plant. 45 figs., 18 tabs.

British Library Electronic Table of Contents (United Kingdom)

Heat transfer through the gas diffusion layer (GDL) is a key process in the design and operation of a PEM fuel cell. The analysis of this process requires determination of the effective thermal conductivity as well as the thermal contact resistance associated with the interface between the GDL and adjacent surfaces/layers. In the present study, a custom-made test bed that allows the separation of effective thermal conductivity and thermal contact resistance in GDLs under vacuum and ambient conditions is described. Measurements under varying compressive loads are performed using Toray carbon paper samples with a porosity of 78% for a range of thicknesses. The measurements are complemented by compact analytical models that achieve good agreement with experimental data. A key finding is that ...

British Library Electronic Table of Contents (United Kingdom)

Until recently, the wavelength-division-multiplexed (WDM) transmission system has reached record capacities and distances due to innovations such as FEC (Forward Error Correction), distributed Raman amplification, new transmission fiber and advanced optical format. Optical-communication systems exclusively employed conventional On-Off Keying signals in either Non-Return-To-Zero (NRZ) or Return-To-Zero (RZ) format. Recently a number of advanced modulation formats have attracted attention. Some of these formats carry information through On-Off-Keying but also modulate the optical phase in order to enhance the robustness of signal to chromatic dispersion, optical filtering and non-linearities. Through extensive sets of simulation results, we showed that it is possible to replace a channel wit...

British Library Electronic Table of Contents (United Kingdom)

The Baobab tree (Adansonia digitata L.) is a key multipurpose species for the African region. In the recent years there has been an extended commercial interest for different A. digitata products. As a spectacular African key species there has been a growing interest from NGO?s and various research groups. A research group, focussing on the following countries Burkina Faso, Mali and Niger, has participated in a concerted research action with cross counter disciplinary cooperation between plant physiology, population genetics, tree breeding, food science, and socioeconomics. This paper presents a review and the way knowledge gaps are being addressed using the above mentioned approach. The overall work was initiated in 2005?2006 when a large collection of A. digitata seeds was carried out in...

British Library Electronic Table of Contents (United Kingdom)

The objective of the present investigation was to develop a Bayesian framework for updating and integrating covariate information into key parameters of metabolizable energy (ME) systems for dairy cows. The study addressed specifically the effects of genetic improvements and feed quality on key parameters in current ME systems. These are net and metabolizable energy for maintenance (NEM and MEM, respectively), efficiency of utilization of ME for milk production (kL) and growth (kG), and efficiency of utilization of body stores for milk production (kT). Data were collated from 38 studies, yielding 701 individual cow observations on milk energy, ME intake, and tissue gain and loss. A function based on a linear relationship between milk energy and ME intake and correcting for tissue energy lo...

Energy Technology Data Exchange (ETDEWEB)

The research has involved the characterization of catalyst acidity, [sup 2]D NMR studies of Bronsted acid sites, and kinetic, calorimetric, and spectroscopic studies of methylamine synthesis and related reactions over acid catalysts. Approach of this work was to explore quantitative correlations between factors that control the generation, type, strength, and catalytic properties of acid sites on zeolite catalysts. Microcalorimetry, thermogravimetric analysis, IR spectroscopy, and NMR spectroscopy have provided information about the nature and strength of acid sites in zeolites. This was vital in understanding the catalytic cycles involved in methylamine synthesis and related reactions over zeolite catalysts.

Science.gov (United States)

Stream temperature is an important physical characteristic of headwater streams that plays a critical role in the presence and health of juvenile salmonids. Headwater stream temperature was documented in two geomorphic settings on the Kenai Peninsula, Alaska, focusing on the variation in temperature induced by diffuse groundwater discharge and variable air temperature. Eighteen headwater stream reaches were studied in four watersheds, with 11 drainageway sites and seven discharge-slope sites. In drainageway sites, low-gradient streams flow through broad valleys with groundwater-fed fen wetlands; in discharge-slope sites, high-gradient streams flow through narrow valleys with groundwater-fed slope wetlands. At all 18 sites, hourly stream temperatures were measured for one year. At one drainageway and one discharge-slope site, groundwater temperatures, stream ...

Energy Technology Data Exchange (ETDEWEB)

Yucca Mountain, Nevada is a potential site for a high-level radioactive-waste repository. Uncertainty and sensitivity analyses were performed to estimate critical factors in the performance of the site with respect to a criterion in terms of pre-waste-emplacement ground-water travel time. The degree of failure in the analytical model to meet the criterion is sensitive to the estimate of fracture porosity in the upper welded unit of the problem domain. Fracture porosity is derived from a number of more fundamental measurements including fracture frequency, fracture orientation, and the moisture-retention characteristic inferred for the fracture domain.

International Nuclear Information System (INIS)

The validation of the forecast model for early emergency response to nuclear accidents is evaluated by trace tests in atmosphere in Daya Bay nuclear power site. The simulation experiment of the Daya Bay nuclear power site shows that the particle spreading image and the time-integrated concentration distribution given by plume concentration prediction model can perform the variation of pathway of the pollutant transport, as well as the effects of topography on transport and diffusion of pollutants. The simulation of five trace tests in field shows that 59.1% of ratios between predicted results and observed results are within the range of 10, and 41% of ratios are within the range of 5 approximately. (authors)

International Nuclear Information System (INIS)

Investigations were carried out of radiation level around Daya Bay for three times since the construction and operation Daya bay Nuclear Power Station and Lingao Nuclear Power Station in Guangdong province in the period of 1988 to 2000. As shown by the investigation, the radiation levels both in the field and indoors remains unchanged by and large but slightly higher than before on the roads. Also this paper gives the analysis of variations in radiation levels form site to site and from time to time. It was shown that, for environmental ? radiation levels measurements, typical measuring sites have significant impact on the meaning results. (authors)