joining pathway choice: Topics by WorldWideScience.org

[Sutureless joining of tissues (review of the literature)].

Full text of publication follows: As SiCf/SiC composites are very low activation materials, their use as structural material for the reactor blanket and first wall components appears essential to demonstrate the potential of D-T fusion power reactor. Positive features of SiCf/SiC are their high performances at elevated operating temperature and the ability to produce a specific component. Critical issues of SiCf/SiC are the mechanical properties, radiation stability and, with regard to technological issues, their hermeticity and joining processes. Improvement of joining processes for SiC/SiC components is also needed. Recently, several blanket designs have been studied: the TAURO blanket concept in the European Union, the ARIESAT concept in the US and the DREAM concept in Japan. In those reactors, hermetic SiCf/SiC or self-sealing coatings are mandatory. The basic idea of self sealing concept is to manufacture a coating with specific ...

2007-12-10

2

Technology and international climate policy

PMID:4882373

1967-07-01

3

Korea Joins International Computing Infrastructure

Both the nature of international climate policy architectures and the development and diffusion of new energy technologies could dramatically influence future costs of reducing global emissions of greenhouse gases. This paper explores the implications of interactions between technology availability and performance and international policy architectures for technology choice and the social cost of limiting atmospheric CO2 concentrations to 500 ppm by the year 2095. Key issues explored in the paper include the role of bioenergy production with CO2 capture and storage (CCS), overshoot concentration pathways, and the sensitivity of mitigation costs to policy and technology.

2006-03-15

4

Social choice and the continuity axiom

... Society Physics Press Release 05-175Korea Joins International Computing Infrastructure ... connectivity with Korea in a ceremony last month. Facilitated by the Korea Institute for Science and ...

5

Norwegian Open Research Archives (NORA)

Full Text Available

6

User's guide on butt heat-fusion joining of polyethylene gas pipes. Topical report, July 1986-September 1989. Volume 1

Technical reference on butt heat-fusion joining of polyethylene gas pipes. Topical report, July 1986-September 1989. Volume 2

Heat fusion is the most common joining method for polyethylene gas distribution piping. Butt fusion was studied with the intent of relating the quality of the joint to the joining conditions. A semi-empirical approach was used. The thermofluid consequences of joining conditions such as heater temperature, heating time and joining parameter were calculated using a computer model. The model was validated by instrumented tests. The strength of the joints was gauged by destructive mechanical testing. Tensile and tensile impact tests were used. Over 150 joints were fabricated using four different polyethylene resins. Most of the data are given in GRI Report No. 88/0276.2 -- Volume 2: Technical Reference on Butt Heat Fusion Joining of Polyethylene Gas Pipes. A parameter, termed the Joining Parameter, was found to characterize the joining ...

1989-09-01

7

Bibliography of the technical literature of the Materials Joining Group, 1951--1991

Heat fusion is the most common joining method for polyethylene gas distribution piping. Butt fusion was studied with the intent of relating the quality of the joint to the joining conditions. A semi-empirical approach was used. The thermofluid consequences of joining conditions such as heater temperature, heating time and joining parameter were calculated using a computer model. The model was validated by instrumented tests. The strength of the joints was gauged by destructive mechanical testing. Tensile and tensile impact tests were used. Over 150 joints were fabricated using four different polyethylene resins. Most of the data are given in GRI Report No. 88/0276.2 -- Volume 2: Technical Reference on Butt Heat Fusion Joining of Polyethylene Gas Pipes. A parameter, termed the Joining Parameter, was found to characterize the joining ...

1989-09-01

8

Structural Stability of a Joined-Wing Sensorcraft

This document contains a listing of the written scientific information originating in the Materials Joining (formerly the Welding and Brazing Group), Metals and Ceramics Division, Oak Ridge National Laboratory during 1951 through June 1991. This registry of documents is as much as possible, in the order of issue date.

1991-12-01

9

Kaiser ANIP Participation, 1954-1962

... core section of the composite sandwich panels (Figure 5). Table 6 shows the properties that buckled as well as their initial ...

2007-06-01

10

Joining of technical ceramics

... joined together by a thin ribbon of glass that is bent into a frame shape in a prior operacion. The three glass pieces are ...

1963-03-31

11

Status and potential of materials development as reflected in steels for the automotive industry; Stand und Potential der Werkstoffentwicklung am Beispiel der Staehle fuer die Automobilindustrie

Large, complex, high purity ceramic shapes are required by a variety of emerging technologies for their electrical insulation and high temperature strength properties coupled with their refractoriness and purity. Ceramic sealant bonding, using crystalline and vitreous sealant materials, has recently shown significant potential for joining technical ceramics to form the required shapes. Materials and techniques for joining technical ceramics including alumina, magnesia, zirconia and thoria are discussed. (orig.).

12

Design and strength evaluation of structural joint made by electro-magnetic forming (EMF)

The high-strength and ultra high-strength steels developed and produced by Thyssen Krupp Stahl make a major contribution to automotive lightweighting. Proven and newly-developed coatings are used to meet increasingly important corrosion protection requirements. Design for materials, optimized forming and joining processes and the use of modern simulation techniques help to exploit the potential of the new steels. Future development work will focus on reducing the density of steels without compromising their well-known advantages - in particular their strength. The use of high-strength and ultra high-strength steels in the automotive industry is on the increase. Steel will remain the material of choice for auto manufacture, above all due to its potential for cost-efficient lightweight construction and its full recyclability. (orig.) [German] Einen wesentlichen Beitrag zum Leichtbau im Automobil leisten die von Thyssen Krupp Stahl entwickelten ...

1999-04-01

13

Ecotoxicology of Explosives

Recently, weight reduction of vehicles has been of great interest, and consequently, the use of low-density materials in the automotive industry is increasing every year. Materials should not be substituted such a way that material of component parts is simply changed because there is a problem in achieving stiffness and strength. To achieve these requirements, the automobile should be redesigned totally. Aluminum spaceframe is rapidly being adopted as a body structure for accommodating lightness, stiffness and strength requirement. In aluminum spaceframe manufacturing, it is often required to join aluminum tube. But there are few suitable methods for joining aluminum tube, so that much interest has been focused on testing suitable joining methods. Joining by electromagnetic forming(EMF) can be useful method in joining aluminum tube, which offers some advantages compared with the ...

2004-06-10

14

Summary of Dissimilar Metal Joining Trials Conducted by Edison Welding Institute

Managing sites contaminated with munitions constituents is an international challenge. Although the choice of approach and the use of Ecological Risk Assessment (ERA) tools may vary from country to country, the assurance of quality and the direction of ecotoxicological research are universally recognized as shared concerns. Drawing on a multidisciplinary team of contributors, 'Ecotoxicology of Explosives' provides comprehensive and critical reviews available to date on fate, transport, and effects of explosives. The book delineates the state of the science of the ecotoxicology of explosives, past, present, and recently developed. It reviews the accessible fate and ecotoxicological data for energetic materials (EMs) and the methods for their development. The chapters characterize the fate of explosives in the environment, then provide information on their ecological effects in key environmental media, including aquatic, sedimentary, and terrestrial ...

2009-04-01

15

Summary of Dissimilar Metal Joining Trials Conducted by Edison Welding Institute

Under the direction of the NASA-Glenn Research Center, the Edison Welding Institute (EWI) in Columbus, OH performed a series of non-fusion joining experiments to determine the feasibility of joining refractory metals or refractory metal alloys to Ni-based superalloys. Results, as reported by EWI, can be found in the project report for EWI Project 48819GTH (Attachment A, at the end of this document), dated October 10, 2005. The three joining methods used in this investigation were inertia welding, magnetic pulse welding, and electro-spark deposition joining. Five materials were used in these experiments: Mo-47Re, T-111, Hastelloy X, Mar M-247 (coarse-grained, 0.5 mm to several millimeter average grain size), and Mar M-247 (fine-grained, approximately 50 (micro)m average grain size). Several iterative trials of each material combination with each joining method were performed to ...

16

Vibration suppressor for a manual perforator

Under the direction of the NASA-Glenn Research Center, the Edison Welding Institute (EWI) in Columbus, OH performed a series of non-fusion joining experiments to determine the feasibility of joining refractory metals or refractory metal alloys to Ni-based superalloys. Results, as reported by EWI, can be found in the project report for EWI Project 48819GTH (Attachment A, at the end of this document), dated October 10, 2005. The three joining methods used in this investigation were inertia welding, magnetic pulse welding, and electro-spark deposition joining. Five materials were used in these experiments: Mo-47Re, T-111, Hastelloy X, Mar M-247 (coarse-grained, 0.5 mm to several millimeter average grain size), and Mar M-247 (fine-grained, approximately 50 {micro}m average grain size). Several iterative trials of each material combination with each joining method were performed to ...

2005-11-18

17

NASA - NASA Explorer Joins Godspeed Commemoration in Alexandria

A device is presented with handle containing hinges and work support arm, a flexible pin with supports and extra weights. The flexible pin is equipped with cantilevered sergments and weights. The bracket hinges on the handle are perpendicular to the axis of the flexible pin. To reduce handle vibration during drilling hard rock, the handle and brackets are joined to allow relative movement on the surface perpendicular to the hinges of the work support arm. The handle is joined to the work support arm parallel to the sides and the work support arm has holes to accomodate this. Elastic bushings are located between the lateral sides of the work support arm where it is joined to the handle.

1983-01-01

18

Experimental Investigation into the Fatigue Life of Hybrid ...

May 25, 2006 ... Former NASA Astronaut Roger Crouch will help open the commemoration of the 400th anniversary of Jamestown in Alexandria, Va., ...

19

COAST and MRO to Join Forces

... asymmetric versions of two different methods of joining GRP composite sandwich panels 3with steel were obtained (see Figure 1.7), the idea being ...

2008-06-01

20

FIBROUS MONOLITH WEAR RESISTANT COMPONENTS FOR THE MINING INDUSTRY

Cambridge scientists in the late 1980's. This same team, then headed by Professor John Baldwin, built the world's first separated-element optical/infrared aperture synthesis...

2011-09-15

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Impact of informed-choice invitations on diabetes screening knowledge, attitude and intentions: an analogue study

A set of materials property data for potential wear resistant materials was collected. These materials are designated for use as the ''core'' materials in the Fibrous Monolith structure. The material properties of hardness, toughness, thermal conductivity and cost were selected as determining factors for material choice. Data for these four properties were normalized, and weighting factors were assigned for each property to establish priority and evaluate the effects of priority fluctuation. Materials were then given a score based on the normalized parameters and weighting values. Using the initial estimates for parameter priority, the highest ranking material was tungsten carbide, with diamond as the second ranked material. Several materials were included in the trade study, and five were selected as promising ''core'' materials to include in this effort. These materials are tungsten carbide, ...

2001-08-15

22

Joining technologies for the plasma facing components of ITER

BackgroundDespite concerns that facilitating informed choice would decrease diabetes screening uptake, 'informed choice' invitations that increased knowledge did not affect attendance...Full Text Available

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An extensive R and D program on the development of the joining technologies between armour (beryllium, tungsten and carbon fibre composites)/copper alloys heat sink and copper alloys/ stainless steel has been carried out by ITER Home Teams. A brief review of this R and D program is presented in this paper. Based on the results, reference technologies for use in ITER have been selected and recommended for further development. (author)

1998-07-01

24

Joined ceramic product

Device for laying cut peat in a drying formation

According to the present invention, a joined product is at least two ceramic parts, specifically bi-element carbide parts with a bond joint therebetween, wherein the bond joint has a metal silicon phase. The bi-element carbide refers to compounds of MC, M.sub.2 C, M.sub.4 C and combinations thereof, where M is a first element and C is carbon. The metal silicon phase may be a metal silicon carbide ternary phase, or a metal silicide.

2001-01-01

25

Development of techniques for joining of high-sensitivity solar cells. Final report; Entwicklung von Verbindungstechniken fuer hoch empfindliche Solarzellen. Abschlussbericht

A device for laying cut peat in drying formations is proposed consisting of separate compartments, reinforced on a common frame and with mechanisms for both vertical and horizontal mixing. In order to intensify the drying process, within the scope of laying cut peat, uniform clearances and spacing in formations is applied. The mixing compartments are joined in sections with capabilities for separate mixing in each unit. The compartments are joined together by hinges and can be turned 180 degrees on the hinges horizontal to the plane.

1980-06-17

26

Bibliography of the technical literature of the Materials Joining Group, Metals and Ceramics Division, 1951--June 1989

The report investigates a number of joining techniques, i.e. isothermal solidification, ultrasonic welding, thermocompression, and glueing. (HW) [Deutsch] In diesem Vorhaben wurden verschiedene Verbindungstechniken untersucht: Isotherme Erstarrung; Ultraschall-Schweissen; Thermokompression; Leitkleben. (HW)

1992-09-01

27

Bibliography of the technical literature of the Materials Joining Group, Metals and Ceramics Division, 1951 through June 1987

This document contains a listing of the written scientific information originating in the Materials Joining (formerly the Welding and Brazing Group), Metals and Ceramics Division, Oak Ridge National Laboratory during 1951 through June 1989. This registry of documents is as much as possible, in the order of issue date. A complete cross-referenced listing of the technical literature of the Metals and Ceramics Division is also available.

1989-10-01

28

The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth

This document contains a listing of the written scientific information originating in the Materials Joining Group (formerly the Welding and Brazing Group), Metals and Ceramics Division, Oak Ridge National Laboratory during 1951 through June 1987. It is a registry of about 400 documents as nearly as possible in the order in which they were issued.

1987-08-01

29

Picornavirus Subversion of the Autophagy Pathway

SummaryThe Hippo tumor-suppressor pathway controls tissue growth in Drosophila and mammals by regulating cell proliferation and apoptosis. The Hippo pathway includes...Full Text Available

2009-07-15

30

Dysregulation of the mevalonate pathway promotes transformation

While autophagy has been shown to act as an anti-viral defense, the Picornaviridae avoid and, in many cases, subvert this pathway to promote their own replication. Evidence indicates...Full Text Available

31

Work and family--allies or enemies? what happens when business professionals confront life choices

The importance of cancer metabolism has been appreciated for many years, but the intricacies of how metabolic pathways interconnect with oncogenic signaling are not fully understood. With a clear understanding...Full Text Available

2010-08-24

32

Performance and Scalability of the NAS Parallel Benchmarks in Java

Work and family--allies or enemies?

2000-01-01

33

Implementation of the NAS Parallel Benchmarks in Java

Several features make Java an attractive choice for scientific applications. In order to gauge the

2002-01-01

34

Choice and meaning in the quantum universe

Several features make Java an attractive choice for High Performance Computing (HPC). In order to

2002-01-01

35

Users' guide on socket heat fusion joining of polyethylene gas pipes. Volume 1. Topical report, September 1989-September 1990

This report discusses whether the events that occur in the universe evolve deterministicly or randomly or both. (LSP).

1992-05-22

36

Technical reference on socket heat fusion joining of polyethylene gas pipes. Volume 2. Topical Report, September 1989-September 1990

The integrity of a pipeline system is determined by its weakest links which may be the joints. Heat fusion is the most common method for joining gas distribution polyethylene (PE) piping. There are procedural, thermal, and mechanical aspects of making fusion joints. Acceptable procedural aspects, such as heater calibration and cleanliness, can be assured by rigorous training and certification of the operators. Thermal and mechanical aspects consist of specifying joining conditions such as the heater temperature, heating time, and joining pressure. In the absence of procedural errors, the strength of a fusion joint should depend on the pipe material, pipe dimensions, and the thermal and mechanical joining conditions. Socket heat fusion was studied both experimentally and analytically to determine how the strength of the joint varied with the conditions under which it was made. The standard tensile impact ...

1991-03-01

37

Shape evolution of nanostructures by thermal and ion beam processing. Modeling and atomistic simulations

The integrity of a pipeline system is determined by its weakest links which may be the joints. Heat fusion is the most common method for joining gas distribution polyethylene (PE) piping. There are procedural, thermal, and mechanical aspects of making fusion joints. Acceptable procedural aspects, such as heater calibration and cleanliness, can be assured by rigorous training and certification of the operators. Thermal and mechanical aspects consist of specifying joining conditions such as the heater temperature, heating time, and joining pressure. In the absence of procedural errors, the strength of a fusion joint should depend on the pipe material, pipe dimensions, and the thermal and mechanical joining conditions. Socket heat fusion was studied both experimentally and analytically to determine how the strength of the joint varied with the conditions under which it was made. The standard tensile impact ...

1991-03-01

38

Vacuum container for use in a thermonuclear device

Single-crystalline nanostructures often exhibit gradients of surface (and/or interface) curvature that emerge from fabrication and growth processes or from thermal fluctuations. Thus, the system-inherent capillary force can initiate morphological transformations during further processing steps or during operation at elevated temperature. Therefore and because of the ongoing miniaturization of functional structures which causes a general rise in surface-to-volume ratios, solid-state capillary phenomena will become increasingly important: On the one hand diffusion-mediated capillary processes can be of practical use in view of non-conventional nanostructure fabrication methods based on self-organization mechanisms, on the other hand they can destroy the integrity of nanostructures which can go along with the failure of functionality. Additionally, capillarity-induced shape transformations are effected and can thereby be controlled by applied fields and forces (guided or driven ...

2009-05-12

39

Manufacture and first wall joining for an ITER primary wall module prototype: R and D phase with small scale mock-ups

Purpose: To enable the use of a vacuum container under a relatively high temperature or a high level radioactive dose. Constitution: Vacuum sealing materials for use in a vacuum container are made of resins such as polyimide and polyamide. The sealing materials are joined to the both surfaces of a plate-like insulator by means of adhesives or sealants, or the sealing materials are joined between two plate-like insulators by means of adhesives or sealants. They are situated within grooves of both of flanges, which are clamped tightly by insulation bolt and nut. Since the vacuum sealing materials are joined to the insulator by means of the adhesives or sealants, the reliability of the vacuum sealing can be improved without impairing the electrical insulation. The resin of the vacuum sealing material can be used for the radiation dose up to 10"8 rad, temperature up to 250"0C or more. (Seki, K.).

1982-04-30

40

Pilot Study of the Treatment of VEGF-Signaling Pathway Inhibitor-Induced Hypertension

In the frame of the Primary Wall Module prototype manufacturing for ITER, a consistent R and D phase was conducted in order to identify the industrial allowable tolerances and manufacturing problems which would occur when joining pieces by HIPping process during the PW module manufacturing. The purpose of this development was to give as industrial as possible manufacturing routes for joining together large Stainless Steel or DS-Copper pieces with Stainless Steel tubes and for bonding Beryllium tiles onto a curved component surface. The study concerned surface preparations, allowable gaps and joint geometry, Beryllium tile geometry, Titanium interlayer thickness, etc. This R and D phase also allowed the development and validation of different ultrasonic inspection tools needed for plate-plate, tube-plate, edge to edge plate bonding.

2001-10-01

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Manganese-enhanced and diffusion tensor MR imaging of the normal, injured and regenerating rat visual pathway

Treatment Induced Hypertension

2011-01-19

42

Norwegian Open Research Archives (NORA)

Full Text Available

43

Enteric neural pathways mediate the anti-inflammatory actions of glucagon-like peptide 2

The kinetic model of the shikimate pathway as a tool to optimize enzyme assays for high-throughput screening.

Udgivelsesdato: 2007/7

2007-01-01

44

Whipple Procedure for Pancreatic Cancer

Four-enzyme section of the shikimate pathway (Aro B, D, E, and K) of Streptococcus pneumoniae has been studied. Kinetic properties of the individual enzymes and three- and four-enzyme linked reactions have been characterized in vitro. On the basis of the data measured in spectrophotometric and LC-MS experiments, kinetic mechanisms of the enzymes have been suggested and all kinetic parameters have been identified. Kinetic models for these three- and four-enzyme sections of the shikimate pathway have been constructed and validated. The model of the four-enzyme section of shikimate pathway has been employed to design an inhibition-sensitive reconstituted pathway for a high-throughput screening effort on the shikimate pathway. It was demonstrated that using the model it was possible to optimize this reconstituted pathway in such a way to provide equal sensitivity of ...

2006-11-01

45

Medline Plus

... be able to watch the many intricate steps Dr. Richard Alexander must accomplish to remove the cancer. ... door to informed medical care. Now let's join Dr. Richard Alexander at the University of Maryland Medical ...

46

Threats and countermeasures for network security

The risk of establishment of aquatic invasive species: joining invasibility and propagule pressure

In the late 1980's, the traditional threat of anonymous break-ins to networked computers was joined by viruses and worms, multiplicative surrogates that carry out the bidding of their authors. Technologies for authentication and secrecy, supplemented by good management practices, are the principal countermeasures. Four articles on these subjects are presented.

1991-01-01

47

Lessons to be Learned from 25 Years of Research Investigating Psychosocial Interventions for Cancer Patients

Invasive species are increasingly becoming a policy priority. This has spurred researchers and managers to try to estimate the risk of invasion. Conceptually, invasions are dependent both on the receiving...Full Text Available

2007-10-22

48

Conducting rigorous psychosocial intervention research with cancer patients has many challenges including encouraging them to join studies, asking them to engage in interventions or be part...Full Text Available

2009-01-01

49

At-Risk Populations

Effects of Daily Morphine Administration and Deprivation on Choice and Demand for Remifentanil and Cocaine in Rhesus Monkeys

... hearing protection since you play, sit or stand near loud instruments and speakers. Here are a few ... piper's calling you to join him" Led Zeppelin (Robert Plant), "Stairway to Heaven" "My ears are ringin' ...

50

Advantage and Choice: Social Relationships and Staff Assistance in Assisted Living

Choice procedures have indicated that the relative reinforcing effectiveness of opioid drugs increases during opioid withdrawal. The demand curve, an absolute measure of reinforcer value, has not been...Full Text Available

2011-01-01

51

KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats

Objectives.To understand how “cumulative inequality” (CI), expressed as individual advantage and choice, and “external social supports” contribute...Full Text Available

2010-05-01

52

British Library Electronic Table of Contents (United Kingdom)

Summary: The KEGG PATHWAY database provides a widely used service for metabolic and nonmetabolic pathways. It contains manually drawn pathway maps with information about the genes, reactions and relations contained therein. To store these pathways, KEGG uses KGML, a proprietary XML-format. Parsers and translators are needed to process the pathway maps for usage in other applications and algorithms. We have developed KEGGtranslator, an easy-to-use stand-alone application that can visualize and convert KGML formatted XML-files into multiple output formats. Unlike other translators, KEGGtranslator supports a plethora of output formats, is able to augment the information in translated documents (e.g. MIRIAM annotations) beyond the scope of the KGML document, and amends missing components to fr...

2011-01-01

53

Prostatectomy

Input price risk and optimal timing of energy investment: choice between fossil- and biofuels

This paper deals with the indications for prostatectomy; the differential diagnosis of the symptomatology of bladder neck obstruction; and the factors influencing the choice of operation....Full Text Available

1973-05-01

54

Pathway analysis for alternate low-level waste disposal methods

We consider energy investment, when a choice has to be made between fossil fuel and biomass fired production technologies. A dynamic model is presented to illustrate the effect of the different degrees of input price uncertainty on the choice of technology and the timing of the investment. It is shown that when the choice of technology is irreversible, it may be optimal to postpone the investment even if it would otherwise be optimal to invest in one or both of the plant types. We provide a numerical example based on cost, estimates of two different power plant types. (author)

2002-05-01

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skittles, a Drosophila phosphatidylinositol 4-phosphate 5-kinase, is required for cell viability, germline development and bristle morphology, but not for neurotransmitter release.

The purpose of this paper is to evaluate a complete set of environmental pathways for disposal options and conditions that the Nuclear Regulatory Commission (NRC) may analyze for a low-level radioactive waste (LLW) license application. The regulations pertaining In the past, shallow-land burial has been used for the disposal of low-level radioactive waste. However, with the advent of the State Compact system of LLW disposal, many alternative technologies may be used. The alternative LLW disposal facilities include below- ground vault, tumulus, above-ground vault, shaft, and mine disposal This paper will form the foundation of an update of the previously developed Sandia National Laboratories (SNL)/NRC LLW performance assessment methodology. Based on the pathway assessment for alternative disposal methods, a determination will be made about whether the current methodology can satisfactorily analyze the pathways and phenomena ...

1992-03-01

56

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing

The phosphatidylinositol pathway is implicated in the regulation of numerous cellular functions and responses to extracellular signals. An important branching point in the pathway is the phosphorylation...Full Text Available

1998-12-01

57

The Requirement for Sodium as a Micronutrient by Species Having the C₄ Dicarboxylic Photosynthetic Pathway

Inhibiting insulin/IGF-1 signalling extends lifespan and delays age-related disease in species throughout the animal kingdom. This life-extension pathway, the first to be defined, was discovered through...Full Text Available

2011-01-12

58

The Heparan and Heparin Metabolism Pathway is Involved in Regulation of Fatty Acid Composition

Six species having characteristics of plants with the C₄ dicarboxylic photosynthetic pathway, Echinochloa utilis L. Ohwi et Yabuno (Japanese millet), Cynodon dactylon...Full Text Available

1972-05-01

59

Stabilization of ?-catenin induces pancreas tumor formation

Six genes involved in the heparan sulfate and heparin metabolism pathway, DSEL (dermatan sulfate epimerase-like), EXTL1 (exostoses (multiple)-like 1), HS6ST1...Full Text Available

60

Select spinal lesions reveal multiple ascending pathways in the rat conveying input from the male genitalia

Background & Aimsβ-catenin signaling within the canonical Wnt pathway is essential for pancreas development. However, the pathway is normally down-regulated...Full Text Available

2008-10-01

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RXR activators molecular signalling: involvement of a PPAR?-dependent pathway in the liver and kidney, evidence for an alternative pathway in the heart

The specific white matter location of all the spinal pathways conveying penile input to the rostral medulla is not known. Our previous studies using rats demonstrated the loss of low but not high threshold...Full Text Available

2010-04-01

62

Pathways, Outcomes, and Costs in Colon Cancer: Retrospective Evaluations in Two Distinct Databases

In this study we compared the molecular signalling elicited by rexinoids, selective retinoid X receptor (RXR)-activators, in several organs (i.e. liver, kidney,...Full Text Available

2003-03-01

63

PDP-1 Links the TGF-? and IIS Pathways to Regulate Longevity, Development, and Metabolism

Purpose:The goal of this study was to use two separate databases to evaluate the clinical outcomes and the economic impact of adherence to Level I Pathways, an evidence-based oncology...Full Text Available

2011-05-01

64

JAK/STAT Pathways in Cytokine Signaling and Myeloproliferative Disorders

The insulin/IGF-1 signaling (IIS) pathway is a conserved regulator of longevity, development, and metabolism. In Caenorhabditis elegans IIS involves activation of DAF-2 (insulin/IGF-1...Full Text Available

2011-04-01

65

Complement-inhibiting and anti-inflammatory properties of chlorazole fast pink 2BL.

Hematopoiesis is the cumulative result of intricately regulated signaling pathways that are mediated by cytokines and their receptors. Studies conducted over the past 10 to 15 years have revealed that...Full Text Available

2010-10-01

66

Atrial natriuretic peptide signal pathway upregulated in stomach of streptozotocin-induced diabetic mice

Chlorazole fast pink 2BL inhibited the classical complement pathway in rat serum both in vivo and in vitro. The in vitro potency of chlorazole fast pink against the alternative pathway could not be...Full Text Available

1981-02-01

67

Preparation of "2"0"3Pb compounds for studies on pathway and effects of lead pollution

AIM: To investigate atrial natriuretic peptide (ANP) secretion from gastric mucosa and the relationship between the ANP/natriuretic peptide receptor type A (NPR-A) pathway and diabetic gastroparesis.METHODS:...Full Text Available

2010-01-07

68

Cholera toxin binding sites in yeast triggers biochemical pathway

... air pollution coprecipitation isotope production lead 203 proton beams

69

Joining of zirconium alloys

... e Biologia Molecular (SBBq), Sao Paulo, SP (Brazil) 217 p. APPLIED LIFE

1998-05-23

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The hippo pathway in biological control and cancer development

Alloys of zirconium are widely used in various core components of power reactors. Nuclear assemblies require high degree of reliability and integrity for performing in radiation and corrosive atmosphere. The hostile environments of reactor core and inaccessibility for repairs make it mandatory to select only those joining techniques which produce not only superior quality but are also amenable to NDT methods and such other techniques which ensure acceptable performance. The author has worked on various types of welding of zirconium alloys for different applications. Modern techniques in electron beam (EB) welding, resistance welding, GTAW welding and laser welding have been developed for joining Zr alloys components for different types of reactors. Many of these have been standardized and successfully used in production. Several advancements have been made in the welding technologies towards achieving high productivity and increased reliability ...

2002-09-11

71

British Library Electronic Table of Contents (United Kingdom)

Abstract The Hippo pathway is an evolutionally conserved protein kinase cascade involved in regulating organ size in vivo and cell contact inhibition in vitro by governing cell proliferation and apoptosis. Deregulation of the Hippo pathway is linked to cancer development. Its first core kinase Warts was identified in Drosophila more than 15 years ago, but it gained much attention when other core components of the pathway were identified 8 years later. Major discoveries of the pathway were made during past several years. The core kinase components Hippo, Salvador, Warts, and Mats in the fly and Mst1/2, WW45, Lats1/2, and Mob1 in mammals phosphorylate and inactivate downstream transcriptional co-activators Yorkie in the fly, Yes-associated protein (YAP) and transcriptional co-activator with ...

2011-01-01

72

Role of death receptor, mitochondrial and endoplasmic reticulum pathways in different stages of degenerative human lumbar disc

British Library Electronic Table of Contents (United Kingdom)

Intervertebral disc (IVD) cell apoptosis has been suggested to play an important role in promoting the degeneration process. It has been demonstrated that IVD cell apoptosis occurs through either death receptor, mitochondrial or endoplasmic reticulum (ER) pathway. Our study aimed to explore the relationship among these three pathways and grade of IVD degeneration (IVDD). IVDs were collected from patients with lumbar fracture, vertebral tumor, disc herniation or spondylolisthesis. IVDs were distinguished by MRI and histomorphological examination, cell apoptosis was detected by TUNEL staining. Biomarkers of these three apoptosis pathways were detected by RT-PCR and Western blot. Furthermore, the correlation between apoptosis pathways biomarkers and disc pathology were analyzed. Nucleus pulpo...

2011-01-01

73

The diffusion bonding and theoretical model including void growth mechanism in magnesium alloys

Overview of the EU small scale mock-up tests for ITER high heat flux components

There are many factors affecting diffusion bonding in order to obtain high quality joining. Therefore, in the beginning, we constructed diffusion bonding model based on void growth mechanism to predict bonding pressures and times. In addition, in order to compare theoretical values with experimental values, diffusion bonding tests were carried out by using commercial AZ31 magnesium alloy sheets with different grain sizes, 16 and 130 {mu}m. The present AZ31 alloys were successfully diffusion bonded at several conditions, and the bonding strength was more than 0.8 of each parent materials. The experimental bonding conditions in high quality joining, times and pressures, were good agreed with prediction analysis. (orig.)

2003-07-01

74

Hot dip galvanised dual phase steels for automotive applications

This task within the EU R and D for ITER was aimed at the development of basic manufacturing solutions for the high heat flux plasma facing components such as the divertor targets, the baffles and limiters. More than 50 representative small-scale mock-ups have been manufactured with beryllium, carbon and tungsten armour using various joining technologies. High heat flux testing of 20 of these mock-ups showed the carbon mono-blocks to be the most robust solution, surviving 2000 cycles at absorbed heat fluxes of up to 24 MW m{sup -2}. With flat armour tiles rapid joint failures occurred at 5-16 MW m{sup -2} depending on joining technology and armour material. These test results serve as a basis for the selection of manufacturing options and materials for the prototypes now being ordered. (orig.) 11 refs.

1998-09-01

75

SR 97 - Alternative models project. Discrete fracture network modelling for performance assessment of Aberg

The automotive industry desires to optimize safety and lightweight construction for the production of cars and trucks. The resulting task for steel suppliers is to make steel grades available that can fulfil these requirements. Different projects have shown optimistic outlooks for optimization of safety and reduction of the weight of automobile bodies by using different high strength and ultra high strength steels. In the last group the dual phase steels play the lead. In recent years different steel grades have been developed and optimized for these applications. On one hand developing the mechanical properties as well as joining and forming of dual phase steels is one of the first steps. On the other hand different coated surfaces for various applications of dual phase steels is another step. Starting with characteristic production conditions for cold rolled hot dip galvanised dual phase steels, the mechanical properties for joining and ...

2005-07-01

76

Ecological response of a multi-purpose river development project using macro-invertebrates richness and fish habitat value

As part of studies into the siting of a deep repository for nuclear waste, Swedish Nuclear Fuel and Waste Management Company (SKB) has commissioned the Alternative Models Project (AMP). The AMP is a comparison of three alternative modeling approaches for geosphere performance assessment for a single hypothetical site. The hypothetical site, arbitrarily named Aberg is based on parameters from the Aespoe Hard Rock Laboratory in southern Sweden. The Aberg model domain, boundary conditions and canister locations are defined as a common reference case to facilitate comparisons between approaches. This report presents the results of a discrete fracture pathways analysis of the Aberg site, within the context of the SR 97 performance assessment exercise. The Aberg discrete fracture network (DFN) site model is based on consensus Aberg parameters related to the Aespoe HRL site. Discrete fracture pathways are identified from canister locations in a ...

1999-08-01

77

Welcome to the Department of Estates - University of Bath

It has been acknowledged that river morphology and hydrology have been intensively altered due to the anthropic demands in floodplain land use and management, flood protection, promotion of navigability or energy production. Rivers were transformed in water highways, having lost contact with their surrounding floodplain as well as the plethora of ecological processes and occupants once thriving in these ecotonal zones. The identification of this emerging threat of morphological and hydrological alteration on ecological integrity adds further complexity in the exploitation of hydrosystem resources. These resources are heavily coveted and guarded by different lobbies each having strategic views on future project development. Stakeholders may want to promote hydro-electricity, ecologists a natural reserve, communes may wish to have an increased flood protection and leisure promoters a nautical center. As a result, the proposition of a river development project is certain to face ...

2002-04-01

78

Seeking nature of God in Big Bang T1 the secrets to the beginning of the universe could lie underground in Switzerland.

...The system recognises the name and confirms it before it starts to dial. To stop the number being dialled say 'cancel'. If ...of the conference : Press the Recall 'R' button and listen for holding dial tone. Select extension or outside number of the person to ...who is going to join the conference Press Recall 'R' to receive dial tone and select '*' and '4'. The call is ...line is faulty and should be reported to the switchboard operators by dialling '0' and giving full details of the fault, the extension ...

79

CERN Multimedia

Joanna Geary joined a Birmingham University team of scientists working on the project in Geneva. Simond Hadley took the pictures. "The most exciting thing of all" says professor Peter Watkins with a smile, "is we have absolutely no idea what will happen until we switch it on."

2008-01-01

80

RESUME-95: Results of an International Field Test of Mobile Equipment for Emergency Response

Phase transitions in multiplicative competitive processes

In 1995 the exercise RESUME-95 (Rapid Environmental Surveying Using Mobile Equipment) took place in Finland. Groups from 8 European countries joined the exercise. The methods used were airborne gamma-ray measurements, car-borne measurements and in situ stationary measurements. The results of the measurements are analyses aiming at disclosing similarities and differences between groups and measuring techniques.

1997-01-01

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81

Overview of advanced techniques for fabrication and testing of ITER multilayer plasma facing walls

We introduce a discrete multiplicative process as a generic model of competition. Players with different abilities successively join the game and compete for finite resources. Emergence of dominant players and evolutionary development occur as a phase transition. The competitive dynamics underlying this transition is understood from a formal analogy to statistical mechanics. The theory is applicable to bacterial competition, predicting novel population dynamics near criticality.

2005-07-01

82

Member Login | Join / Register with EUGRIS

The design of the ITER primary first wall incorporates a multi-layered structure consisting of a layer of beryllium bonded to a layer of copper alloy with embedded stainless steel tubes which in turn is bonded to a stainless steel structure. In this configuration, the stainless steel provides structural support, the copper alloy improved resistance to high heat loads, and the beryllium layer a low Z metal interface with plasma. Fabrication, testing and control of this multi-layered structure, and indeed the entire blanket shield module, calls for advanced methods. Several associations in the four home teams and their industrial partners have been involved in various fabrication and joining tasks now grouped under L4 blanket project. In this paper, an overview of the work done so far for joining stainless steel to stainless steel, stainless steel to copper alloy, copper alloy to copper alloy, and copper alloy to beryllium is presented. ...

1998-09-01

83

Calcium fluoride window mounting

...In 2000, the Water Framework Directive (WFD) came into force, introducing a comprehensive, river basin based water management for Europe. The aim of the Directive is ...In 2000, the Water Framework Directive (WFD) came into force, introducing a comprehensive, river basin based water management for Europe. The aim of the Directive ...

84

Why the United States Must Deploy a National Missile ...

A technique has been developed for joining a large calcium fluoride crystal to a stainless-steel flange by means of a silver transition ring. The process involves both vacuum brazing using a copper-silver alloy and air brazing using silver chloride. This paper describes the procedure used in fabricating a high-vacuum leak-tight calcium fluoride window assembly.

85

Vehicle-Dependent Disposition Kinetics of Fluoranthene in Fisher-344 Rats

... transItion to more capable space-based interceptors as ... ten wtth bmlogtcal, and thirty with chemical weapons. ... are becoming the weapon of choice ...

2011-05-14

86

Sperm competition risk affects male mate choice copying

The objective of this study was to evaluate how the vehicles of choice affect the pharmacokinetics of orally administered Fluoranthene [FLA] in rats. Fluoranthene is a member of the family of...Full Text Available

2008-03-01

87

British Library Electronic Table of Contents (United Kingdom)

Mate choice copying was mostly described as a strategy employed by females to assess the quality of potential mates, but also males can copy other males? mate choice. An open question in this context is whether and how copying males evaluate sperm competition risk, as mating with a female that has already copulated with another male obviously sets the stage for intense sperm competition (i.e., in species with internal fertilization). Using the livebearing Atlantic molly (Poecilia mexicana) as a model, we asked (a) whether males of that species indeed copy other males? choices, and if they do so, (b) whether copying males strategically adjust their behavior to sperm competition risk. We used an approach where focal males could first choose to associate with a large or a small stimulus femal...

2011-01-01

88

PyMVPA: A Unifying Approach to the Analysis of Neuroscientific Data

Pharmacological optimization of tissue perfusion

The Python programming language is steadily increasing in popularity as the language of choice for scientific computing. The ability of this scripting environment to access a huge code base in various...Full Text Available

89

Minimally Invasive Parathyroidectomy Using Surgical Sonography

After fluid resuscitation, vasoactive drug treatment represents the major cornerstone for correcting any major impairment of the circulation. However, debate still rages as to the choice of agent, dose,...Full Text Available

2009-07-01

90

Autologous blood pleurodesis: A good choice in patients with persistent air leak

Minimally invasive parathyroidectomy is the procedure of choice for primary hyperparathyroidism due to parathyroid adenoma. Localization of the offending adenoma in minimally invasive parathyroidectomy...Full Text Available

91

Analysis of Online Algorithms for Organ Allocation.

AIM:The study compares the efficiency, side effects and complications of autologous blood pleurodesis with talcum powder and tetracycline.MATERIALS...Full Text Available

2009-10-01

92

Amazon.com: Chicken Soup for the Soul: Power Moms - 101 Stories Celebrating the Power of Choice for Stay-at-Home and Work-from-Home Moms (97819350963

... on some results we obtained, using stochastic methods as ... choice between two customers in a queue and one ... with the terminal of edge I being the ...

1990-10-03

93

Age Preservation of the Syntactic Processor in Production

...com: Chicken Soup for the Soul: Power Moms - 101 Stories Celebrating the Power of Choice for Stay-at-Home and Work-from-Home Moms (9781935096313)...com: Chicken Soup for the Soul: Power Moms - 101 Stories Celebrating the Power of Choice for Stay-at-Home and Work-from-Home Moms (9781935096313)...Victor Hansen, Wendy Walker: Books Jack Canfield, Mark Victor Hansen, Wendy Walker,Chicken Soup for the Soul: Power Moms - 101 Stories Celebrating ...the Power of Choice for Stay-at-Home and Work- from-Home Moms,Chicken Soup for the Soul,1935096311,I9781935096313,Child Care/Parenting,Employment,Literary collections,Motherhood,...

94

The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism

Two experiments are reported on the influence of cognitive aging on grammatical choice in language production. In both experiments, participants from two age-groups (young and old) produced...Full Text Available

2003-09-01

95

The androgen receptor governs the execution, but not programming, of male sexual and territorial behaviors

Several enzymes of the metabolic pathways responsible for metabolism of cytosolic ribonucleotides and deoxyribonucleotides are located in mitochondria. Studies described in this paper suggest dysfunction of the mitochondria to affect these metabolic pathways and limit the available levels of cytosolic ribonucleotides and deoxyribonucleotides, which in turn can result in aberrant RNA and DNA synthesis. Mitochondrial dysfunction has been linked to genomic instability, and it is possible that the limiting effect of mitochondrial dysfunction on the levels of nucleotides and resulting aberrant RNA and DNA synthesis in part can be responsible for this link. This paper summarizes the parts of the metabolic pathways responsible for nucleotide metabolism that can be affected by mitochondrial dysfunction.

2010-01-01

96

Temperature stabilization, ocean heat uptake and radiative forcing overshoot profiles

SUMMARYTestosterone and estrogen are essential for male behaviors in vertebrates. How these two signaling pathways interact to control masculinization of the brain and behavior...Full Text Available

2010-04-29

97

British Library Electronic Table of Contents (United Kingdom)

Political leaders in numerous nations argue for an upper limit of the global average surface temperature of 2 K above the pre-industrial level, in order to attempt to avoid the most serious impacts of climate change. This paper analyzes what this limit implies in terms of radiative forcing, emissions pathways and abatement costs, for a range of assumptions on rate of ocean heat uptake and climate sensitivity. The primary aim is to analyze the importance of ocean heat uptake for radiative forcing pathways that temporarily overshoot the long-run stabilization forcing, yet keep the temperature increase at or below the 2 K limit. In order to generate such pathways, an integrated climate-economy model, MiMiC, is used, in which the emissions pathways generated represent the least-cost solution o...

2011-01-01

98

Telomeres and telomerase in cancer

Technology Improvement Pathways to Cost-Effective Vehicle Electrification: Preprint

Myriad genetic and epigenetic alterations are required to drive normal cells toward malignant transformation. These somatic events commandeer many signaling pathways that cooperate to endow aspiring...Full Text Available

2010-01-01

99

Physiology of the Autonomic Nervous System

This paper evaluates several approaches aimed at making plug-in electric vehicles (EV) and plug-in hybrid electric vehicles (PHEVs) cost-effective.

2010-02-01

100

Phenolic compounds in ectomycorrhizal interaction of lignin modified silver birch

This manuscript discusses the physiology of the autonomic nervous system (ANS). The following topics are presented: regulation of activity; efferent pathways; sympathetic and parasympathetic divisions;...Full Text Available

2007-08-15

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101

Pathway analysis: aquatic plants imported in 10 EPPO countries

BackgroundThe monolignol biosynthetic pathway interconnects with the biosynthesis of other secondary phenolic metabolites, such as cinnamic acid derivatives, flavonoids and condensed...Full Text Available

102

British Library Electronic Table of Contents (United Kingdom)

Pathway analyses are regarded by National Plant Protection Organizations as a very efficient way to address the risks posed by invasive alien species. Data on import of aquatic plants was obtained from 10 EPPO countries (Austria, Czech Republic, Estonia, France, Germany, Hungary, the Netherlands, Latvia, Switzerland and Turkey) and aggregated in order to consider whether invasive or potentially invasive alien plants could be introduced in the EPPO region through this pathway. This study highlights that this pathway mainly consists of the import of tropical plants for use in aquaria, and which do not represent a risk due to their climatic requirements. However, a few species require thorough attention owing to the threats they cause. Of the 247 species recorded as imported, only 10 are curr...

2009-01-01

103

Oxidation of ethane by an Acremonium species.

Liver Carcinogenesis Unit

Ethane oxidation was studied in ethane-grown resting cells (mycelia) of an Acremonium sp. and in cell-free preparations of such mycelia. From resting cell experiments evidence was found for a pathway...Full Text Available

1976-07-01

104

Genomics of human longevity

The Liver Carcinogenesis Section uses the modern technologies of molecular biology, cell biology, protein chemistry and genetics to investigate the biochemical and genetic pathways involved in human liver cancer.

105

Foodstuff Concentrations and Relocation Considerations Following a Tritium Oxide Release from SRS Tritium Facilities

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences...Full Text Available

2011-01-12

106

Far-out Pathways to Space: Great Guns? - ISTP

The ingestion pathway consequences following an accidental tritium release from the Savannah River Site Tritium Facilities are evaluated.

1999-05-18

107

Far-out Pathways to Space: Great Guns?

The SHARP cannon. Hydrogen is compressed in the tube on top, the gun barrel is on bottom. When Jules Verne wrote in 1865 "From Earth to the Moon" he ...

108

Characteristics of compounds that cross the blood-brain barrier

Turbine Afterword The SHARP cannon. Hydrogen is compressed in the tube on top, the gun barrel is on bottom. When Jules Verne wrote in 1865 "From Earth to the Moon" he envisioned...

2011-09-03

109

Biosynthesis and metabolism of salicylic acid.

Substances cross the blood-brain barrier (BBB) by a variety of mechanisms. These include transmembrane diffusion, saturable transporters, adsorptive endocytosis, and the extracellular pathways. Here,...Full Text Available

110

Activation of the alternative pathway of complement by mycobacteria and cord factor.

Pathways of salicylic acid (SA) biosynthesis and metabolism in tobacco have been recently identified. SA, an endogenous regulator of disease resistance, is a product of phenylpropanoid metabolism formed...Full Text Available

1995-05-09

111

A $G_{4}$ Sequence within PHR1 Promoter Acts as a Gate for Cross-Talks between Damage-Signaling Pathway and Multi-Stress Response

The ability of a number of mycobacteria and some of their components to activate complement was examined. Mycobacterium bovis BCG (Glaxo strain), Mycobacterium leprae, Mycobacterium lepraemurium, and...Full Text Available

1980-07-01

112

KoreaScience (Korea)

Full Text Available

2002-09-01

113

Revegetation of inactive U-tailing sites

Synergistic Activation of Glucose-6-Phosphate Dehydrogenase and NAD(P)H oxidase by Src kinase Elevates Superoxide in Type 2 Diabetic, Zucker fa/fa, Rat Liver

Soil placed over any sealant/barrier system can provide a protective mantle if the soil is not lost by erosion. Vegetation is an attractive choice for controlling erosion because it can provide an economical self-renewing cover that serves to reduce erosion by both wind and water. The objective of this research and development effort is to select and test vegetation strategies, including the choice of species and methods for revegetation that are compatible with sealant/barrier systems and are suited to soils and climates at inactive uranium mill tailings sites.

1981-02-01

114

Signal transduction pathway controlling synthesis of a class of degradative enzymes in Bacillus subtilis: expression of the regulatory genes and analysis of mutations in degS and degU.

Glucose metabolism through glycolysis and hexosamine pathway has been shown to be altered in type 2 diabetes. However, its fate through the pentose phosphate pathway (PPP) is currently unclear....Full Text Available

2009-08-01

115

Regulation of Indole-3-Acetic Acid Biosynthetic Pathways in Carrot Cell Cultures ¹

The rates of synthesis of a class of both secreted and intracellular degradative enzymes in Bacillus subtilis are controlled by a signal transduction pathway defined by at least four regulatory genes:...Full Text Available

1990-02-01

116

How does immune challenge inhibit ingestion of palatable food? Evidence that systemic lipopolysaccharide treatment modulates key nodal points of feeding neurocircuitry

2,4-Dichlorophenoxyacetic acid (2,4-D) promotes the accumulation of tryptophan-derived indole-3-acetic acid (IAA) in carrot cell cultures during callus proliferation by a biosynthetic pathway that is...Full Text Available

1992-11-01

117

Differential regulation of the biosynthesis of glucose transporters by the PI3-K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla.

Immune challenge induces behavioral changes including reduced ingestion of palatable food. Multiple pathways likely contribute to this effect, including viscerosensory pathways controlling hypothalamic...Full Text Available

2008-11-01

118

Comparative transcriptional pathway bioinformatic analysis of dietary restriction, Sir2, p53 and resveratrol life span extension in Drosophila

The insulin signaling pathway, involving protein kinase B (PKB) and mitogen-activated protein kinase (MAPK), mediates the biological response to insulin and several growth factors and cytokines. To investigate the correlation between glucose transporter (Glut) biosynthesis and the insulin signaling pathway activated by novel compounds of Liriope platyphylla (LP9M80-H), alterations in Glut and key protein expression in the insulin signaling pathway were analyzed in the liver and brain of ICR mice treated with LP9M80-H. An in vitro assay showed that the highest level of insulin concentration was observed in the LP9M80-H-treated group, followed by the LP-H, LP-M, LP-E, and LP9M80-C-treated groups. Therefore, LP9M80-H was selected for use in studying the detailed mechanism of the insulin signaling pathway in animal systems. In an in vivo experiment, LP9M80-H induced a significant increase in glucose levels ...

2010-12-14

119

The requirement for sodium as a micronutrient by species having the c(4) dicarboxylic photosynthetic pathway.

A multiple comparison approach using whole genome transcriptional arrays was used to identify genes and pathways involved in calorie restriction/dietary restriction (DR) life span extension in Drosophila....Full Text Available

2011-03-15

120

The Requirement for Sodium as a Micronutrient by Species Having the C4 Dicarboxylic Photosynthetic Pathway

Six species having characteristics of plants with the C(4) dicarboxylic photosynthetic pathway, Echinochloa utilis L. Ohwi et Yabuno (Japanese millet), Cynodon dactylon L. (Bermuda grass), Kyllinga brevifolia Rottb., Amaranthus tricolor L. cv. Early splendour, Kochia childsii Hort., and Portulaca grandiflora Hook (rose moss), responded decisively to 0.1 milliequivalent per liter NaCl supplied to their culture solutions initially containing less than 0.08 microequivalent per liter Na. Chlorosis and necrosis occurred in leaves of plants not receiving sodium. Portulaca failed to set flower in the sodium-deficient cultures. Under similar conditions Poa pratensis L. (Kentucky blue grass) having characteristics of the C(3) photosynthetic pathway made normal growth and did not respond to the addition of sodium. It is concluded from these results and previously reported work that sodium is generally essential for species having the C(4) ...

1972-05-01

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121

Theoretical nuclear physics. Final report

Six species having characteristics of plants with the C4 dicarboxylic photosynthetic pathway, Echinochloa utilis L. Ohwi et Yabuno (Japanese millet), Cynodon dactylon L. (Bermuda grass), Kyllinga brevifolia Rottb., Amaranthus tricolor L. cv. Early splendour, Kochia childsii Hort., and Portulaca grandiflora Hook (rose moss), responded decisively to 0.1 milliequivalent per liter NaCl supplied to their culture solutions initially containing less than 0.08 microequivalent per liter Na. Chlorosis and necrosis occurred in leaves of plants not receiving sodium. Portulaca failed to set flower in the sodium-deficient cultures. Under similar conditions Poa pratensis L. (Kentucky blue grass) having characteristics of the C3 photosynthetic pathway made normal growth and did not respond to the addition of sodium. It is concluded from these results and previously reported work that sodium is generally essential for species having the C4 ...

1972-01-01

122

Molecular resemblance of an AIDS-associated lymphoma and endemic Burkitt lymphomas: Implications for their pathogenesis

As the three-year period FY93-FY96 ended, there were six senior investigators on the grant full-time: Bulgac, Henley, Miller, Savage, van Kolck and Wilets. This represents an increase of two members from the previous three-year period, achieved with only a two percent increase over the budget for FY90-FY93. In addition, the permanent staff of the Institute for Nuclear Theory (George Bertsch, Wick Haxton, and David Kaplan) continued to be intimately associated with our physics research efforts. Aurel Bulgac joined the Group in September, 1993 as an assistant professor, with promotion requested by the Department and College of Arts and Sciences by September, 1997. Martin Savage, who was at Carnegie-Mellon University, jointed the Physics Department in September, 1996. U. van Kolck continued as research assistant professor, and we were supporting one postdoctoral research associate, Vesteinn Thorssen, who joined us in September, 1995. Seven ...

1997-05-01

123

Status of R and D of the plasma facing components for the ITER divertor

Non-Hodgkin lymphoma is a common feature of AIDS. Approximately 30-40% of these tumors exhibit clinical features suggestive of endemic Burkitt lymphoma: they are aggressive malignancies that occur in association with Epstein-Barr virus infection, they arise in the setting of immunosuppression, and they carry t(8;14) translocations without detectable rearrangement of the MYC oncogene. To understand the molecular basis of these parallels, the authors analyzed a case of Epstein-Barr-positive AIDS-associated undifferentiated lymphoma. Southern blots show that the tumor exhibits immunoglobulin joining segment rearrangement but no rearrangement of the MYC oncogene. Cloning of the rearranged joining segment allowed the isolation of recombinant clones encompassing the translocation breakpoint, and sequencing of the translocation junction disclosed that the breakpoint is situated 7 base pairs from the chromosome 14 site involved in a previously ...

124

Simple method for high-temperature separation of thallium isotopes from a bulk lead target

The paper reports the progress made by the ITER Home Teams in the development of robust carbon and tungsten armoured plasma facing components for the ITER divertor. The activities on the development and study of armour materials, joining technologies, non-destructive evaluation techniques, high heat flux testing of manufactured components and neutron irradiation resistance studies are presented. The results of these activities confirm the feasibility of the main divertor components. Examples of the fruitful collaboration between Parties and future R and D needs are also described. (author)

2001-05-01

125

Simple method for high-temperature separation of thallium isotopes from a bulk lead target

A method is proposed for the quantitative isolation of radiothallium in gas form from proton-bombarded lead of mass up to 20 g. The molten lead is kept at about 800 K in hydrofluoric-acid vapor (HF/H/sub 2/O approx. = 1) at a reduced pressure (less than or equal to4 Pa). We used 99.9% lead with the U-240 cyclotron at the Nuclear Research Institute, Academy of Sciences of the Ukrainian SSR, or the phasotron at the Join Nuclear Research Institute, which gave protons at 65 and 680 MeV correspondingly.

1988-03-01

126

Preparation of monoclonal antibodies labelled by astatine

A method is proposed for the quantitative isolation of radiothallium in gas form from proton-bombarded lead of mass up to 20 g. The molten lead is kept at about 800 K in hydrofluoric-acid vapor (HF/H_2O #approx =# 1) at a reduced pressure (#<=#4 Pa). We used 99.9% lead with the U-240 cyclotron at the Nuclear Research Institute, Academy of Sciences of the Ukrainian SSR, or the phasotron at the Join Nuclear Research Institute, which gave protons at 65 and 680 MeV correspondingly.

127

Preliminary Investigations of Joining Technologies for Attaching Refractory Metals to Ni-Based Superalloys

Astatine conversed into cationic form is shown to form stable complex with diethylenetriaminpentacetic acid. Due to this complex astatine joins RN_2 type monoclonal antibodies. More favorable conditions to prepare astatine labelled antibodies are found. Chromatographical analysis and electromigration experiments have shown that astatine is strongly retained in in-vitro biomolecule. Astatine did not escape from the labelled antibodies even in case of urea effect on them. Immune activity of astatine labelled antibodies remained similar in 20 h. 28 refs., 4 figs.

128

Magnetically-impelled arc butt welding of automobile parts

In this study, a range of joining technologies has been investigated for creating attachments between refractory metal and Ni-based superalloys. Refractory materials of interest include Mo-47%Re, T-111, and Ta-10%W. The Ni-based superalloys include Hastelloy X and MarM 247. During joining with conventional processes, these materials have potential for a range of solidification and intermetallic formation-related defects. For this study, three non-conventional joining technologies were evaluated. These included inertia welding, electro-spark deposition (ESD) welding, and magnetic pulse welding (MPW). The developed inertia welding practice closely paralleled that typically used for the refractory metals alloys. Metallographic investigations showed that forging during inertia welding occurred predominantly on the refractory metal side. It was also noted that at least some degree of forging on the Ni-based superalloy side of ...

2006-01-20

129

Insulated letter drop plate

Results of an investigation of the weldability of compact hollow automobile parts are reported. The use of magnetically impelled arc butt (MIAB) welding for a piston rod (OD_22_mm x 2.2_mm thickness), a shock-absorber (OD 40 mm x 2.2 mm) and a torque rod (OD 34 mm x 6 mm) has been investigated. Metallographic examination and comprehensive mechanical testing has been conducted to demonstrate the effectiveness of the method for joining of these types of automobile components

2010-01-01

130

INSPIRE - The Next-Generation HEP Information System

An insulated letter drop plate comprises a back plate having an opening for the mail having two hinges at its upper part to attach a cover to; a frame for retaining a first insulation around its perimeter and around the opening; and suitable insulation. This back plate is also provided with an upper curved extension to cover and conceal said hinges. A cover is provided with two complementary hinges to be articulated with the first hinges on the back plate, and with a frame around the perimeter for the retention of a second insulation. A wire joins the first and second hinges, and a coil spring on the wire keeps the cover normally closed.

1988-09-06

131

Diffusion bonding on superplastic-aluminum and -magnesium alloys

CERN, DESY, Fermilab and SLAC have joined forces to build INSPIRE, the next-generation HEP information platform offering innovative tools for information discovery and communication. Representing a natural community-based evolution of SPIRES, INSPIRE provides fast access to the entire body of HEP literature. As a subject repository it will host fulltexts of preprints, Open Access journal articles and supplementary material like conference slides and multimedia, enabling novel text- and data mining applications. In the spirit of Web2.0 INSPIRE will also supply tools for collaboration and user-enriched content.

2010-01-01

132

Asymptotically Optimal Tree-based Group Key Management Schemes

The superplastic characteristics and diffusion bonding behaviors were investigated in commercial 7475 aluminum alloy and AZ31 magnesium alloy sheets. In this study, the presently used materials behaved in a superplastic manner at {proportional_to} 773 K (7475Al) and {proportional_to} 523 K (AZ31). Then, by the theoretical relationship between pressure and time, these materials were successfully diffusion bonded at the superplastic temperatures. The bonding strength was more than 65 MPa. The experimental bonding conditions in high quality joining, times and pressures, were good agreed with prediction analysis. (orig.)

2004-07-01

133

Radiation therapy and Ewing's sarcoma in childhood

In key management schemes that realize secure multicast communications encrypted by group keys on a public network, tree structures are often used to update the group keys efficiently. Selcuk and Sidhu have proposed an efficient scheme which updates dynamically the tree structures based on the withdrawal probabilities of members. In this paper, it is shown that Selcuk-Sidhu scheme is asymptotically optimal for the cost of withdrawal. Furthermore, a new key management scheme, which takes account of key update costs of joining in addition to withdrawal, is proposed. It is proved that the proposed scheme is also asymptotically optimal, and it is shown by simulation that it can attain good performance for nonasymptotic cases.

2005-01-01

134

Quantification of the influence of the choice of the algorithm and planning system on the calculation of a treatment plan

Despite high local control rate in Ewing's sarcoma the exact indication of radiation therapy is still controversial as well as the choice of the target volume and the optimal dose of radiation. The importance of the quality of radiotherapy has been stressed in recently published data and has shown a significant impact on long term local control with adequate radiation therapy. The dramatic improvement of precision allowed by the conformal therapy and three dimensional dosimetry allow to expect a decrease of late effects expected for second malignancies. However, late sequelae and radio-induced osteosarcoma still remain the major side effects after radiotherapy. The authors discuss the results of the main trials on Ewing's sarcoma on the choice of dose and target volume. Surgery is still the preferred choice for small tumors if the foreseen outcome is identical. (authors). 28 refs.

135

Understanding how out of pocket expenses, treatment value and patient characteristics influence treatment choices

In this work an analysis of the influence of the choice of the algorithm or planning system, on the calculus of the same treatment plan is introduced. For this purpose specific software has been developed for comparing plans of a series of IMRT cases of prostate and head and neck cancer calculated using the convolution, superposition and fast superposition algorithms implemented in the XiO 4.40 planning system (CMS). It has also been used for the comparison of the same treatment plan for lung pathology calculated in XiO with the mentioned algorithms, and calculated in the Plan 4.1 planning system (Brainlab) using its pencil beam algorithm. Differences in dose among the treatment plans have been quantified using a set of metrics. The recommendation for the dosimetrist of a careful choice of the algorithm has been numerically confirmed. (Author).

136

Survey of Anesthetic Choice among Fellows of the American Dental Society of Anesthesiology

PURPOSECost-sharing, intended to control the “over-use” of healthcare resources, may also reduce utilization of necessary services. The influence...Full Text Available

2010-01-01

137

Sequential effects in two-choice reaction time tasks: Decomposition and synthesis of mechanisms

Two hundred and fifty Fellows of the American Dental Society of Anesthesiology were surveyed concerning their personal preference of anesthetic technique, regional versus general anesthesia, through...Full Text Available

1988-09-01

138

Role of ankle taping and bracing in the athlete.

Performance on serial tasks is influenced by first- and higher-order sequential effects, respectively due to the immediately previous and earlier trials. As response-to-stimulus interval (RSI)...Full Text Available

2009-09-01

139

Rational design of DNA sequences for nanotechnology, microarrays and molecular computers using Eulerian graphs

Adhesive tape is often used to help athletes recover from ligament sprains of the ankle or to prevent further injury. The choice of taping technique or material is often decided by personal preference,...Full Text Available

1997-06-01

140

Range-Adapting Representation of Economic Value in the Orbitofrontal Cortex

Nucleic acids are molecules of choice for both established and emerging nanoscale technologies. These technologies benefit from large functional densities of ‘DNA processing elements’...Full Text Available

2004-01-01

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141

Percutaneous core excision and radiofrequency thermo-coagulation for the ablation of osteoid osteoma of the spine

While making economic choices, individuals assign subjective values to the available options. Values computed in different behavioral conditions, however, can vary substantially. The same person...Full Text Available

2009-11-04

142

Measuring the efficacy of anti-malarial drugs in vivo: quantitative PCR measurement of parasite clearance

Percutaneous radiofrequency ablation is the treatment of choice for osteoid osteoma of the appendicular skeleton. However, difficulties in localizing the lesion in the spine and its proximity to neural...Full Text Available

2009-03-01

143

Materials choices for the advanced LWR steam generators

BackgroundArtemisinin-based combination therapy, currently considered the therapy of choice for uncomplicated Plasmodium falciparum malaria in endemic countries,...Full Text Available

144

Labeled Products and Our Partners | Design for the Environment...

Current light water reactor (LWR) steam generators have been affected by a variety of corrosion and mechanical damage degradation mechanisms. Included are wear caused by tube vibration, intergranular corrosion, pitting, and thinning or wastage of the steam generator tubing and accelerated corrosion of carbon steel supports (denting). The Electric Power Research Institute (EPRI) and the Steam Generator Owners Groups (I, II) have sponsored laboratory and field studies to provide ameliorative actions for the majority of the damage forms experienced to date. Some of the current corrosion mechanisms are aggravated or caused by unique materials choices or materials interactions. New materials have been proposed and at least partially qualified for use in replacement model steam generators, including an advanced LWR design. In so far as possible, the materials choices for the advanced LWR steam generator avoid the corrosion pitfalls seemingly inherent ...

1987-11-15

145

Interactions of Antibiotics and Methanolic Crude Extracts of Afzelia Africana (Smith.) Against Drug Resistance Bacterial Isolates

choice Charlotte NC *ecosential for smooth cooktops 2010 Jelmar, LLC Skokie IL CLR Cooktop Cleaner 2004 LotusLand Products, LLC Dallas TX *Believe -- BeSpicy Oven and Grill...

2011-08-18

146

IDEAS: Agricultural Systems, Elsevier

Infection due to multidrug resistance pathogens is difficult to manage due to bacterial virulence factors and because of a relatively limited choice of antimicrobial agents. Thus, it is imperative to...Full Text Available

147

Human choice and climate change. Volume 2: Resources and technology

... (restricted)] 256-264 Influence of likelihood function choice for estimating crop model parameters using the generalized likelihood uncertainty estimation method by He, Jianqiang & Jones, James W. & Graham, Wendy D. & Dukes, Michael D. [Downloadable! (restricted)]...

148

Exploring the impact of a decision support intervention on vascular access decisions in chronic hemodialysis patients: study protocol

Foreward: Preface; Introduction; The natural science of global climate change; Land and water use; Coastal zones and oceans; Energy and industry; Energy and social systems; Technological change; and Sponsoring organizations, International Advisory Board, and project participants.

1997-12-31

149

Exactly solvable field-theoretical model with tachyons

BackgroundIn patients with Stage 5 Chronic Kidney Disease who require renal replacement therapy a major decision concerns modality choice. However, many patients defer the decision...Full Text Available

150

Dorsal cortex volume in male side-blotched lizards (Uta stansburiana) is associated with different space use strategies

Explicit soliton solutions describing the inelastic interaction between sub- and superluminal particles are found within the framework of a new integrable model of relativistic classical field theory. The corresponding energies are nonnegative irrespective of the choice of reference frame.

1988-09-01

151

Determinants of Appropriate Child Health and Nutrition Practices among Women in Rural Gambia

Spatial abilities have been associated with many ecologically-relevant behaviors such as territoriality, mate choice, navigation and acquisition of food resources. Differential demands on spatial...Full Text Available

2009-07-01

152

Delayed choice responding by pigeons when the correct response is not predictable from the sample stimulus.

Health education and awareness involves providing knowledge about causes of illness and choices to promote a change in individual behaviour and, thus, improves survival of individuals. Studies have,...Full Text Available

2010-04-01

153

Coulomb scattering for scalar field in Schroedinger picture

Food-deprived pigeons were presented with a row of four response keys situated above a grain hopper aperture. At the start of a trial, three of four keys were randomly selected and illuminated white...Full Text Available

1982-01-01

154

Consumer preferences for electric vehicles. Final report

The scattering of a charged scalar field on Coulomb potential on de Sitter space-time is studied using the solution of the free Klein-Gordon equation. We find that the scattering amplitude is independent of the choice of the picture and in addition the total energy is conserved in the scattering process.

2008-07-31

155

Construction of a Continuous Wave Frequency Modulation ...

A small-sample survey of consumer preferences for a second car - featuring both conventional and electric vehicle choices - indicates a proelectric bias. The potential of electric cars in the utility market largely depends on dramatic improvements in battery technology and the right mix of electricity and gasoline prices.

1986-06-01

156

Consideration of radiation effects in the choice of packaging materials

... Steady State 16.0-28.0 5.05 to 5.36 0 Key switch turned on. ... version may have been the better choice since the acousto-optic modulator also ...

1997-03-01

157

Climate Change, Genetics or Human Choice: Why Were the Shells of Mankind's Earliest Ornament Larger in the Pleistocene Than in the Holocene?

Requirements for food packaging materials include whether there is any interaction between the food and the package during or after the irradiation, and whether as a result of the irradiation, volatile or leachable substances are released from the pack into the food. The performance of cellulose-based materials and plastic films under irradiation are discussed.

158

Choosing a future for epidemiology: I. Eras and paradigms.

BackgroundThe southern African tick shell, Nassarius kraussianus (Dunker, 1846), has been identified as being the earliest known ornamental object used by human...Full Text Available

159

Becoming a general practitioner - Which factors have most impact on career choice of medical students?

To inform choices about the future of epidemiology, the present condition of epidemiology is examined, in terms of its evolution through three eras, each demarcated by its own paradigm: (1) the era...Full Text Available

1996-05-01

160

An unusual presentation of pancreatic pseudocyst mimicking cystic neoplasm of the pancreas: a case report

BackgroundIn Germany, there is a shortage of young physicians in several specialties, the situation of general practitioners (GP) being especially precarious. The factors influencing...Full Text Available

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161

An Evaluation of the Value of Choice with Preschool Children

In spite of their rarity, cystic neoplasms of the pancreas are characterized by existing or potential malignancy that cannot be ignored during decisive process with regard to the choice of treatment....Full Text Available

162

A novel school-based intervention to improve nutrition knowledge in children: cluster randomised controlled trial

The current study examined the reinforcing effects of choosing among alternatives in a four-part evaluation. In the first study, initial-link responses in a concurrent-chains arrangement resulted in...Full Text Available

2006-01-01

163

A Preference for a Sexual Signal Keeps Females Safe

BackgroundImproving nutrition knowledge among children may help them to make healthier food choices. The aim of this study was to assess the effectiveness and acceptability of a...Full Text Available

164

Quantum-chemical investigation of mechanism of dehydroxylation of crystalline and amorphous aluminosilicates

Predation is generally thought to constrain sexual selection by female choice and limit the evolution of conspicuous sexual signals. Under high predation risk, females usually become less choosy, because...Full Text Available

165

Care programmes and integrated care pathways

Within the framework of the cluster approach and the semiempirical SCF MO LCAO method in the CNDO/BW valence approximation, possible pathways have been compared for the dehydroxylation of aluminosilicate systems. It has been shown that dehydroxylation as a result of splitting of a water molecule from an acidic bridge hydroxyl group and a more basic terminal group Al-OH is the most energyfavorable. Apparently, such a dehydroxylation pathway is primarily characteristic for amorphous aluminosilicates. Typical of crystalline aluminosilicates at moderate heat-treating temperature is dehydroxylation through splitting of a water molecule from an acidic bridge hydroxyl group and a neutral Si-OH group; at higher temperatures, there is a possible pathway of dehydroxylation of highsilica zeolites as a result of condensation of two acidic surface hydroxyls.

1986-07-01

166

British Library Electronic Table of Contents (United Kingdom)

Purpose - The article discusses how care programmes and integrated care pathways can be linked, finding ways to improve healthcare process professional and logistical quality from a supply chain and a network point-of-view. Design/methodology/approach - The authors argue that owing to cost containment goals and increasing healthcare demand, healthcare services systems are challenged to improve service quality, whilst at the same time finding ways to improve delivery processes. It explores if the combination of two instruments, care programmes and integrated care pathways, can meet both goals. This combination is illustrated by an example from the Institute of Mental Health Care Eindhoven en de Kempen. Findings - Analysis suggests that care programmes can be combined with integrated care pa...

2008-01-01

167

Ag/C nanoparticles as an cathode catalyst for a zinc-air battery with a flowing alkaline electrolyte

The green power option to gain market advantage

The cyclic voltammetry indicated that the oxygen reduction reaction (ORR) proceeded by the four-electron pathway mechanism on larger Ag particles (174 nm), and that the ORR proceeded by the four-electron pathway and the two-electron pathway mechanisms on finer Ag particles (4.1 nm), simultaneously. The kinetics towards ORR was measured at a rotating disk electrode (RDE) with Ag/C electrode. The number of exchanged electrons for the ORR was found to be close to four on larger Ag particles (174 nm) and close to three on finer Ag particles (4.1 nm). The zinc-air battery with Ag/C catalysts (25.9 nm) was fabricated and examined. (author)

2009-09-05

168

On the Expressive Power of Polyadic Synchronisation in ?- calculus

Deregulation of the electric power industry in Alberta holds the prospect of providing greater choice for customers. One such option will be `green power` which is provided by renewable energy technologies. The energy produced would be without environmental impacts such as air emissions, water pollution, flooding, thermal emissions or waste by-products. Wind power, small scale hydro power, photovoltaics and biomass technologies have been termed as `green power`. The choices that customers make will not be focused on price alone. Market forces are emerging to demand reduction in emissions which will result in a market for `green energy` products and facilitate achieving goals for a sustainable future.

1997-03-01

169

Compressed hydrogen fuelled vehicles: reasons of a choice and developments in ENEA

We extend the pi-calculus with polyadic synchronisation, a generalisation of the communication mechanism which allows channel names to be composite. We show that this operator embeds nicely in the theory of pi-calculus, we suggest that it permits divergence-free encodings of distributed calculi, and we show that a limited form of polyadic synchronisation can be encoded weakly in pi-calculus. After showing that matching cannot be derived in pi-calculus, we compare the expressivity of polyadic synchronisation, mixed choice and matching. In particular we show that the degree of synchronisation of a language increases its expressive power by means of a separation result in the style of Palamidessi's result for mixed choice.

2002-01-01

170

Coherent state quantum key distribution with multi letter phase-shift keying

Some recent achievements in the field of high pressure vessels and safety devices have offered a concrete chance to the application of compressed hydrogen for fleet commercial vehicles for urban use. Accordingly with this concept, ENEA has modified a Fiat Ducato van with a dual fuel engine, retaining the gasoline tank for long distance travelling and adopting the external mixture formation technique, with hydrogen injectors developed by ENEA, for non-polluting short-range duties in urban traffic. The article deals with the rationale for this choice and gives a general view of the project. (author)

1996-12-01

171

Choice of distance from radiation source to tested object for gamma-absorption density measurer in divergent pencil of ray

We present a protocol for quantum key distribution using discrete modulation of coherent states of light. Information is encoded in the variable phase of coherent states which can be chosen from a regular discrete set ranging from binary to continuous modulation similar to phase-shift keying in classical communication. Information is decoded by simultaneous homodyne measurement of both quadratures and requires no active choice of basis. The protocol utilizes either direct or reverse reconciliation both with and without postselection. We analyze the security of the protocol and show how to enhance it by the optimal choice of all variable parameters of the quantum signal.

2010-05-01

172

Wnt3a Induces Myofibroblast Differentiation by Upregulating TGF-? Signaling Through SMAD2 in a ?-Catenin-Dependent Manner

Formulae are derived for estimation of the effect of gamma beam divergence on the value of systematic and statistical components of the errors of density measurement in production of structural materials and products also in the process of exploitation of building structures and constructions. Engineering technique for choice of the distance between radiation source and object under test is developed for absorption radioisotope densimeter operating by the scheme of geometry of divergent beam with amplitude compensation of backscattered radiation effect. The assessment of radioisotope densimeter efficiency providing the error of density measurement prescribed at design stage

173

VAGUS NERVE STIMULATION REGULATES HEMOSTASIS IN SWINE

Growing evidence suggests the Wnt family of secreted glycoproteins and their associated signaling pathways, linked to development, are recapitulated during wound repair and regeneration events. However,...Full Text Available

174

Use of Forward Genetics to Discover Novel Regulators of NF-?B

The central nervous system regulates peripheral immune responses via the vagus nerve, the primary neural component of the cholinergic anti-inflammatory pathway. Electrical stimulation of the...Full Text Available

2010-06-01

175

Uptake of injected 125I-ricin by rat liver in vivo. Subcellular distribution and characterization of the internalized ligand.

Forward and reverse genetic experiments have both played important roles in revealing critical aspects of mammalian signal transduction pathways in cell culture experiments. Only recently have we begun...Full Text Available

2010-06-01

176

Tumour suppressor ING1b maintains genomic stability upon replication stress

Subcellular-fractionation techniques were used to characterize the endocytic pathway followed by ricin in rat liver in vivo and tentatively identify the site(s) at which the ricin interchain disulphide...Full Text Available

1992-05-15

177

Towards computational prediction of microRNA function and activity

The lesion bypass pathway, which is regulated by monoubiquitination of proliferating cell nuclear antigen (PCNA), is essential for resolving replication stalling due to DNA lesions. This process is...Full Text Available

2011-05-01

178

Thermosensitive TRP channel pore turret is part of the temperature activation pathway

While it has been established that microRNAs (miRNAs) play key roles throughout development and are dysregulated in many human pathologies, the specific processes and pathways regulated by individual...Full Text Available

2010-08-01

179

The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

Temperature sensing is crucial for homeotherms, including human beings, to maintain a stable body core temperature and respond to the ambient environment. A group of exquisitely temperature-sensitive...Full Text Available

2010-04-13

180

The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome

Purpose of ReviewThe vertebrate cap’n’collar family transcription factor Nrf2 and its invertebrate homologs SKN-1 (in worms) and CncC (in flies) function...Full Text Available

2011-01-01

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181

The mitochondrial p53 pathway

FRAXA is one of a number of fragile sites in human chromosomes that are induced by agents like fluorodeoxyuridine (FdU) that affect intracellular thymidylate levels. FRAXA coincides with a >200...Full Text Available

2009-07-01

182

The inhibition of tumor cell intravasation and subsequent metastasis through the regulation of in vivo tumor cell motility by the tetraspanin CD151

p53 is one of the most mutated tumor suppressors in human cancers and as such has been intensively studied for a long time. p53 is a major orchestrator of the cellular response to a broad array...Full Text Available

2009-05-01

183

The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae

SummaryIn vivo tumor cell migration through integrin-dependent pathways is key to the metastatic behavior of malignant cells. Using quantitative in vivo...Full Text Available

2008-03-01

184

The brown adipocyte differentiation pathway in birds: An evolutionary road not taken

The target of rapamycin (TOR) pathway regulates cell growth and aging in various organisms. In Saccharomyces cerevisiae, silent information regulator 2 (Sir2) modulates cellular senescence. Moreover,...Full Text Available

185

The Pseudoreceptor BMP and Activin Membrane-bound Inhibitor Positively Modulates Wnt/?-Catenin Signaling*

BackgroundThermogenic brown adipose tissue has never been described in birds or other non-mammalian vertebrates. Brown adipocytes in mammals are distinguished from the more common...Full Text Available

186

The Organizational Hypothesis and Final Common Pathways: Sexual Differentiation of the Spinal Cord and PeripheralNervous System

The canonical Wnt/β-catenin pathway plays a pivotal role in regulating embryogenesis and tumorigenesis by promoting cell proliferation. BAMBI (BMP and activin membrane-bound inhibitor) has...Full Text Available

2008-11-28

187

Targeting the p53 Pathway in Ewing Sarcoma

In honor of the 50^th anniversary of the “organizational hypothesis,” this paper reviews work on sexual differentiation of the spinal cord and peripheral nervous system....Full Text Available

2009-05-01

188

Targeting the Pentose Phosphate Pathway in Syndrome X-related Cardiovascular Complications

The p53 tumour suppressor plays a pivotal role in the prevention of oncogenic transformation. Cancers frequently evade the potent antitumour surveillance mechanisms of p53 through mutation of the TP53...Full Text Available

2011-01-01

189

Synergistic Operation of the CAR2 (Ornithine Transaminase) Promoter Elements in Saccharomyces cerevisiae

Syndrome X is a combination or co-occurrence of several known cardiovascular risk factors (including central obesity, dyslipidemias, fatty liver disease, hyperinsulinemia, insulin resistance,...Full Text Available

2010-05-01

190

Synapse-Associated Protein 102/dlgh3 Couples the NMDA Receptor to Specific Plasticity Pathways and Learning Strategies

Dal82p binds to the UIS_ALL sites of allophanate-induced genes of the allantoin-degradative pathway and functions synergistically with the GATA family Gln3p and Gat1p transcriptional...Full Text Available

1999-11-01

191

Substance P Signaling Contributes to Granuloma Formation in Taenia crassiceps Infection, a Murine Model of Cysticercosis

Understanding the mechanisms whereby information encoded within patterns of action potentials is deciphered by neurons is central to cognitive psychology. The multiprotein complexes formed by...Full Text Available

2007-03-07

192

Structural Characterization and Expression Analysis of the SERK/SERL Gene Family in Rice (Oryza sativa)

Cysticercosis is an infection with larval cysts of the cestode Taenia solium. Through pathways that are incompletely understood, dying parasites initiate a granulomatous reaction that,...Full Text Available

2010-01-01

193

Soluble Variants of Rhodobacter capsulatus Membrane-anchored Cytochrome c_y Are Efficient Photosynthetic Electron Carriers*

Somatic embryogenesis (SE) is the developmental restructuring of somatic cells towards the embryogenic pathway and forms the basis of cellular totipotency in angiosperms. With the availability of full-length...Full Text Available

2009-01-01

194

Scientists seek to turn methanol glut to profit

Photosynthetic (Ps) electron transport pathways often contain multiple electron carriers with overlapping functions. Here we focus on two c-type cytochromes (cyt) in facultative phototrophic...Full Text Available

2008-05-16

195

Regulation of Energy Metabolism Pathways by Estrogens and Estrogenic Chemicals and Potential Implications in Obesity Associated with Increased Exposure to Endocrine Disruptors

French scientists think they have discovered one of the key steps in the methanol-to-gasoline reaction pathway and their British counterparts have learned a new way of converting methanol into acetic acid without carbon monoxide.

1984-11-18

196

Proteasomal chymotrypsin-like peptidase activity is required for essential functions of human monocyte-derived dendritic cells

The prevalence of obesity among children, adolescents and adults has been dramatically increasing worldwide during the last several decades. The obesity epidemic has been recognized as one of...Full Text Available

2009-07-01

197

Prostaglandin-mediated closure of paracellular pathway and not restitution is the primary determinant of barrier recovery in acutely injured porcine ileum

The ubiquitin–proteasome pathway is the principal system for extralysosomal protein degradation in eukaryotic cells, and is essential for the regulation and maintenance of basic cellular processes,...Full Text Available

2007-01-01

198

Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex

SUMMARYSmall bowel epithelium is at the frontline of intestinal barrier function. Restitution is considered to be the major determinant of epithelial repair as function recovers...Full Text Available

2003-11-01

199

Potassium channels as a potential therapeutic target for trigeminal neuropathic and inflammatory pain

Rapamycin inhibits the mTOR (target of rapamycin) pathway and extends lifespan in multiple species. The tuberous sclerosis complex (TSC) protein is a negative regulator of mTOR. In humans, loss of the...Full Text Available

200

Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study

Previous studies in several different trigeminal nerve injury/inflammation models indicated that the hyperexcitability of primary afferent neurons contributes to the pain pathway underlying mechanical...Full Text Available

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201

Pathway to Licensure for Protective Antigen-based Anthrax Vaccines ...

Human longevity is in part genetically determined, and the insulin/IGF-1 signal transduction (IIS) pathway has consistently been implicated. In humans, type 2 diabetes is a frequent disease that results...Full Text Available

202

Pathway of Sugar Transport in Germinating Wheat Seeds

... Weiss, S., D. Kobiler, H. Levy, H. Marcus, A. Pass, N. Rothschild, and Z ... of Bacillus anthracis spores conferred by a protective antigen-based vaccine in rabbits ...

203

PGM2 overexpression improves anaerobic galactose fermentation in Saccharomyces cerevisiae

Three homeologous genes encoding a sucrose (Suc) transporter (SUT) in hexaploid wheat (Triticum aestivum), TaSUT1A, 1B, and 1D, were...Full Text Available

2006-08-01

204

Opposing function of mitochondrial prohibitin in aging

BackgroundIn Saccharomyces cerevisiae galactose is initially metabolized through the Leloir pathway after which glucose 6-phosphate enters glycolysis. Galactose...Full Text Available

205

Neuronatin: A New Inflammation Gene Expressed on the Aortic Endothelium of Diabetic Mice

While specific signalling cascades involved in aging, such as the insulin/IGF-1 pathway, are well-described, the actual metabolic changes they elicit to prolong lifespan remain obscure. Nevertheless,...Full Text Available

206

NASA Materials, Structures, Mechanical Systems, & Manufacturing ...

OBJECTIVE—Identification of arterial genes and pathways altered in obesity and diabetes.RESEARCH DESIGN AND METHODS—Aortic gene expression profiles of...Full Text Available

2008-10-01

207

considers a wide range of pathways to advance the nation's current capabilities. The present ... opment of new energy sources, aging infrastruc- ture and ... and manufacturing TA strategic roadmap as brief- ..... pellant storage and transport. ...

208

NAME=\\

Molecular mechanisms of genetic adaptation to xenobiotic compounds.

...this pathway study the following two focus modules (in addition to the six core modules) and carry out a research investigation within this theme: Agricultural Production Systems Considers the type of farming systems that have evolved globally in relation to the prevailing agro-climatic zones, the influences of economic factors ...

209

Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines

Microorganisms in the environment can often adapt to use xenobiotic chemicals as novel growth and energy substrates. Specialized enzyme systems and metabolic pathways for the degradation of man-made...Full Text Available

1992-12-01

210

Molecular cloning and functional expression of geranylgeranyl pyrophosphate synthase from Coleus forskohlii Briq

BackgroundThe zebrafish is recognized as a versatile cancer and drug screening model. However, it is not known whether the estrogen-responsive genes and signaling pathways that are...Full Text Available

211

BackgroundIsopentenyl diphosphate (IPP), a common biosynthetic precursor to the labdane diterpene forskolin, has been biosynthesised via a non-mevalonate pathway. Geranylgeranyl...Full Text Available

212

Metabolism of Cytokinin

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways

As part of the study of cytokinin metabolic pathways, an enzyme, adenosine phosphorylase (EC 2.4.2.-), which catalyzed the ribosylation of N⁶-(Δ²-isopentenyl)adenine,...Full Text Available

1978-12-01

213

Maturation of GABAergic Inhibition Promotes Strengthening of Temporally Coherent Inputs among Convergent Pathways

Melanoma is one of the most aggressive cancers, and its incidence is increasing. These tumors derive from the melanocyte lineage and remain incurable after metastasis. Here we report that SONIC HEDGEHOG...Full Text Available

2007-04-03

214

Mapping Drug Physico-Chemical Features to Pathway Activity Reveals Molecular Networks Linked to Toxicity Outcome

Spike-timing-dependent plasticity (STDP), a form of Hebbian plasticity, is inherently stabilizing. Whether and how GABAergic inhibition influences STDP is not well understood. Using a model neuron driven...Full Text Available

2010-06-01

215

Lnk constrains myeloproliferative diseases in mice

The identification of predictive biomarkers is at the core of modern toxicology. So far, a number of approaches have been proposed. These rely on statistical inference of toxicity response from either...Full Text Available

216

Late onset muscle plasticity in the whisker pad of enucleated rats

Hematopoietic stem and progenitor cell (HSPC) expansion is regulated by intrinsic signaling pathways activated by cytokines. The intracellular kinase JAK2 plays an essential role in cytokine signaling,...Full Text Available

2010-06-01

217

Lack of association between polymorphisms in C4b-binding protein and atypical haemolytic uraemic syndrome in the Spanish population

Blindness leads to a major reorganization of neural pathways associated with touch. Because incoming somatosensory information influences motor output, it is plausible that motor plasticity occurs in...Full Text Available

2008-10-14

218

Ixodes scapularis tick serine proteinase inhibitor (serpin) gene family; annotation and transcriptional analysis

Dysregulation of the alternative pathway of complement activation, caused by mutations or polymorphisms in the genes encoding factor H, membrane co-factor protein, factor I or factor B, is associated...Full Text Available

2009-01-01

219

Involvement of the NF-?B pathway in multidrug resistance induced by HBx in a hepatoma cell line.

BackgroundSerine proteinase inhibitors (Serpins) are a large superfamily of structurally related, but functionally diverse proteins that control essential proteolytic pathways in...Full Text Available

220

Involvement of chlA, E, M, and N loci in Escherichia coli molybdopterin biosynthesis.

Summary.? It is widely believed that hepatocellular cancer (HCC), especially HBV associated HCC, is highly resistant to chemotherapy. To investigate the molecular influence of HBx protein on multidrug resistance (MDR) in HCC and the potential role of the NF-?B pathway in this process. We established HBx-expressing cells by liposome-mediated transfection of the HBx into the HepG2 cell line. We found that HBx expression in HCC cells induces drug resistance against multiple drugs, a significantly lower apoptosis ratio in HepG2-HBx and HepG2.2.15 cells, compared with HepG2 and HepG2-3.1 cells (P?HCC cells were downregulated by IMD-0354 treatment, which is the NF-?B pathway inhibitor. Taken together, these results suggest that HBx protein might be one of the causes for the occurrence of MDR in HCC, and the NF-?B pathway might be involved in this change. PMID:21914061

2011-05-27

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221

Intermediates of Salicylic Acid Biosynthesis in Tobacco1

All molybdenum enzymes except nitrogenase contain a common molybdenum cofactor, whose organic moiety is a novel pterin called molybdopterin (MPT). To assist in elucidating the biosynthetic pathway of...Full Text Available

1987-01-01

222

In vivo expression and mitochondrial targeting of yeast apoiso-1-cytochrome c fusion proteins.

Salicylic acid (SA) is an important component of systemic-acquired resistance in plants. It is synthesized from benzoic acid (BA) as part of the phenylpropanoid pathway. Benzaldehyde (BD), a potential...Full Text Available

1998-10-01

223

In Vivo Reconstitution of ?-Secretase in Drosophila Results in Substrate Specificity?

To define the import pathway for apoiso-1-cytochrome c in vivo, the coding region for bacterial chloramphenicol acetyltransferase (CAT) or yeast copper metallothionein (CuMT) was fused to the carboxy...Full Text Available

1990-11-01

224

Immunolocalization of phospho-S6 kinases: a new way to detect mitosis in tissue sections and in cell culture

The intramembrane aspartyl protease γ-secretase plays a fundamental role in several signaling pathways involved in cellular differentiation and has been linked with a variety of human diseases,...Full Text Available

2010-07-01

225

Identification of inhibitors of auxin transcriptional activation by means of chemical genetics in Arabidopsis

During a study on the mTor pathway in the rat kidney we observed a striking increase of the phosphorylation of the S6 kinase in mitosis. In cryostat sections of perfusion-fixed tissue mitotic cells...Full Text Available

2007-02-01

226

Hierarchical and serial processing in the spatial auditory cortical pathway is degraded by natural aging

Auxin modulates diverse plant developmental pathways through direct transcriptional regulation and cooperative signaling with other plant hormones. Genetic and biochemical approaches have clarified...Full Text Available

2004-10-12

227

Heterogeneity of the supramammillary-hippocampal pathways: Evidence for a unique GABAergic neurotransmitter phenotype and regional differences

The compromised abilities to localize sounds and to understand speech are two hallmark deficits in aged individuals. The auditory cortex is necessary for these processes, yet we know little...Full Text Available

2010-11-03

228

Helicobacter pylori infection, oncogenic pathways and epigenetic mechanisms in gastric carcinogenesis

The supramammillary nucleus (SuM) provides substantial projections to the hippocampal formation. This hypothalamic structure is involved in the regulation of hippocampal theta rhythm and therefore...Full Text Available

2010-09-01

229

Genetic Heterogeneity in Severe Congenital Neutropenia: How Many Aberrant Pathways Can Kill a Neutrophil?

Chronic colonization of the human stomach by Helicobacter pylori, a Gram-negative bacterium, is the major cause of chronic gastritis, peptic ulcers and gastric cancer. Recent...Full Text Available

2010-05-01

230

Gadolinium-containing phosphatidylserine liposomes for molecular imaging of atherosclerosis

Purpose of reviewSevere congenital neutropenia (SCN) is a primary immunodeficiency in which lack of neutrophils causes inadequate innate immune host response to bacterial...Full Text Available

2007-12-01

231

Evolution of macromolecular import pathways in mitochondria, hydrogenosomes and mitosomes

Exteriorized phosphatidylserine (PS) residues in apoptotic cells trigger rapid phagocytosis by macrophage scavenger receptor pathways. Mimicking apoptosis with liposomes containing PS may represent...Full Text Available

2009-11-01

232

Evolution and Optimality of Similar Neural Mechanisms for Perception and Action during Search

All eukaryotes require mitochondria for survival and growth. The origin of mitochondria can be traced down to a single endosymbiotic event between two probably prokaryotic organisms. Subsequent evolution...Full Text Available

2010-03-12

233

Evidence of perturbations of cell cycle and DNA repair pathways as a consequence of human and murine NF1-haploinsufficiency

A prevailing theory proposes that the brain's two visual pathways, the ventral and dorsal, lead to differing visual processing and world representations for conscious perception than those for action....Full Text Available

2010-09-01

234

Enhanced Levels of the Aroma and Flavor Compound S-Linalool by Metabolic Engineering of the Terpenoid Pathway in Tomato Fruits1

BackgroundNeurofibromatosis type 1 (NF1) is a common monogenic tumor-predisposition disorder that arises secondary to mutations in the tumor suppressor gene NF1....Full Text Available

235

EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Anti-Lipogenic Therapy

The aromas of fruits, vegetables, and flowers are mixtures of volatile metabolites, often present in parts per billion levels or less. We show here that tomato (Lycopersicon esculentum...Full Text Available

2001-11-01

236

Differential Regulation of Mitogen-Activated Protein Kinase Pathways by Acetaminophen and Its Nonhepatotoxic Regioisomer 3?-Hydroxyacetanilide in TAMH Cells

Glioblastoma, the most common malignant brain tumor, is among the most lethal and difficult cancers to treat. Although epidermal growth factor receptor (EGFR) mutations are frequent in glioblastoma,...Full Text Available

237

Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer

Acetaminophen (APAP), a widely used analgesic and antipyretic that is considered to be relatively safe at recommended doses, is the leading cause of drug-induced liver failure in the United States....Full Text Available

2010-07-01

238

Defects in the Secretory Pathway and High Ca²⁺ Induce Multiple P-bodies

The p21-activated kinases (PAKs), immediate downstream effectors of the small G-proteins of the Rac/cdc42 family, are critical mediators of signaling pathways regulating cellular behaviors and...Full Text Available

2010-09-01

239

Control of wrist position and muscle relaxation by shifting spatial frames of reference for motoneuronal recruitment: possible involvement of corticospinal pathways

mRNA is sequestered and turned over in cytoplasmic processing bodies (PBs), which are induced by various cellular stresses. Unexpectedly, in Saccharomyces cerevisiae, mutants of the...Full Text Available

2010-08-01

240

Computational promoter analysis of mouse, rat and human antimicrobial peptide-coding genes

It has previously been established that muscles become active in response to deviations from a threshold (referent) position of the body or its segments, and that intentional motor actions result from...Full Text Available

2010-05-01

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241

Citrate Uptake in Exchange with Intermediates in the Citrate Metabolic Pathway in Lactococcus lactis IL1403?

BackgroundMammalian antimicrobial peptides (AMPs) are effectors of the innate immune response. A multitude of signals coming from pathways of mammalian pathogen/pattern recognition...Full Text Available

242

Chronic inflammation and estradiol interact through MAPK activation to affect TMJ nociceptive processing by trigeminal caudalis neurons

Carbohydrate/citrate cometabolism in Lactococcus lactis results in the formation of the flavor compound acetoin. Resting cells of strain IL1403(pFL3) rapidly consumed citrate while...Full Text Available

2011-02-01

243

Cell proliferation depends on mitochondrial Ca²⁺ uptake: inhibition by salicylate

The mitogen-activated protein kinase/extracellular regulated kinase (MAPK/ERK) pathway plays a key role in mediating estrogen actions in the brain and neuronal sensitization during inflammation....Full Text Available

2009-12-29

244

Catabolite Repression of the Citrate Fermentation Genes in Klebsiella pneumoniae: Evidence for Involvement of the Cyclic AMP Receptor Protein

Store-operated Ca²⁺ entry (SOCE) is a ubiquitous Ca²⁺ influx pathway involved in control of multiple cellular and physiological processes including cell proliferation. Recent evidence...Full Text Available

2006-02-15

245

Carotenoid Crystal Formation in Arabidopsis and Carrot Roots Caused by Increased Phytoene Synthase Protein Levels

Klebsiella pneumoniae is able to grow anaerobically with citrate as a sole carbon and energy source by a fermentative pathway involving the Na⁺-dependent citrate...Full Text Available

2001-09-01

246

CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway

BackgroundAs the first pathway-specific enzyme in carotenoid biosynthesis, phytoene synthase (PSY) is a prime regulatory target. This includes a number of biotechnological approaches...Full Text Available

247

Biosynthetic Pathway of Insect Juvenile Hormone III in Cell Suspension Cultures of the Sedge Cyperus iria1

Recently, CID755673 was reported to act as a highly selective inhibitor of protein kinase D (PKD). In the course of experiments using CID755673, we noticed that it exerted unexpected stimulatory...Full Text Available

2010-01-01

248

Betaxanthins as Substrates for Tyrosinase. An Approach to the Role of Tyrosinase in the Biosynthetic Pathway of Betalains1

In most insect species, juvenile hormones regulate critical physiological processes such as metamorphosis and reproduction. In insects, these sesquiterpenoids are synthesized by retrocerebral endocrine...Full Text Available

2001-10-01

249

BFL: a node and edge betweenness based fast layout algorithm for large scale networks

Tyrosinase or polyphenol oxidase (EC 1.14.18.1) is the key enzyme in melanin biosynthesis and in the enzymatic browning of fruits and vegetables. The role of tyrosinase in the secondary metabolism of...Full Text Available

2005-05-01

250

Autophosphorylation Within the Atg1 Activation Loop Is Required for Both Kinase Activity and the Induction of Autophagy in Saccharomyces cerevisiae

BackgroundNetwork visualization would serve as a useful first step for analysis. However, current graph layout algorithms for biological pathways are insensitive to biologically...Full Text Available

251

Autoantibodies to BRAF, a new family of autoantibodies associated with rheumatoid arthritis

Autophagy is an evolutionarily conserved degradative pathway that has been implicated in a number of physiological events important for human health. This process was originally identified as a response...Full Text Available

2010-07-01

252

Attenuation of Cocaine's Reinforcing and Discriminative Stimulus Effects via Muscarinic M₁ Acetylcholine Receptor StimulationS?

IntroductionBRAF (v raf murine sarcoma viral oncogene homologue B1) is a serine-threonine kinase involved in the mitogen-activated protein kinase (MAPK) signalling pathway, known...Full Text Available

2010-01-01

253

Aspartate Carbamyltransferase 1

Muscarinic cholinergic receptors modulate dopaminergic function in brain pathways thought to mediate cocaine's abuse-related effects. Here, we sought to confirm and ...Full Text Available

2010-01-01

254

Arabidopsis thaliana auxotrophs reveal a tryptophan-independent biosynthetic pathway for indole-3-acetic acid.

Lovatt et al. (1979 Plant Physiol 64: 562-569) have previously demonstrated that end-product inhibition functions as a mechanism regulating the activity of the orotic acid pathway in...Full Text Available

1984-07-01

255

Anxiety in Patients with Cardiac Disease.

We used tryptophan auxotrophs of the dicot Arabidopsis thaliana (wall cress) to determine whether tryptophan has the capacity to serve as a precursor to the auxin, indole-3-acetic acid (IAA). Quantitative...Full Text Available

1993-11-01

256

Analyzing the Light Energy Distribution in the Photosynthetic Apparatus of C4 Plants Using Highly Purified Mesophyll and Bundle-Sheath Thylakoids.

Anxiety may cause adverse outcomes through physiologic pathways in patients with cardiac disease. The purpose of this dissertation was to investigate anxiety and its correlates in persons with acute myocardial infarction (AMI) and heart failure (HF). The ...

2005-01-01

257

Analysis of control methods: mercury and cadmium pollution.

The chlorophyll fluorescence characteristics of mesophyll and bundle-sheath thylakoids from plant species with the C4 dicarboxylic acid pathway of photosynthesis were investigated using flow cytometry....Full Text Available

1996-11-01

258

An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer

Physical system conceptual models are developed to illustrate the various interconnecting pathways of metal flow. Economic use of mercury and cadmium, as representative toxic heavy metals, is inventoried,...Full Text Available

1975-12-01

259

Akt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease

BackgroundGenomics has substantially changed our approach to cancer research. Gene expression profiling, for example, has been utilized to delineate subtypes of cancer, and facilitated...Full Text Available

260

Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network

Atherosclerosis is an inflammatory process leading to enhanced cellular proliferation, apoptosis, and vasa vasorum (VV) neovascularization. While both diabetes mellitus (DM) and hypercholesterolemia...Full Text Available

2010-09-01

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261

Activation of the alternate complement pathway in Staph. aureus infective endocarditis and its relationship to thrombocytopenia, coagulation abnormalities, and acute glomerulonephritis.

A remarkable discovery of recent years is that, despite the complexity of ageing, simple genetic interventions can increase lifespan and improve health during ageing in laboratory animals. The pathways...Full Text Available

2011-05-01

262

ALTERATION OF THE PKC-MEDIATED SIGNALING PATHWAY FOR SMOOTH MUSCLE CONTRACTION IN OBSTRUCTION-INDUCED HYPERTROPHY OF THE URINARY BLADDER

Twenty-four patients with infective endocarditis (IE) are described, fourteen with Staph. aureus and ten with other organisms. Despite the acute nature of the infection, ten of the fourteen with Staph....Full Text Available

1978-11-01

263

A novel fluorescent pH probe for expression in plants

Normal urinary bladder function requires contraction and relaxation of the detrusor smooth muscle (DSM). The DSM undergoes compensatory hypertrophy in response to partial bladder outlet obstruction...Full Text Available

2009-07-01

264

?Activation of the mitogen-activated protein kinase pathways by heat shock

BackgroundThe pH is an important parameter controlling many metabolic and signalling pathways in living cells. Recombinant fluorescent pH indicators (pHluorins) have come into vogue...Full Text Available

265

Regulation of Redd1 Expression by Hypoxia

In addition to inducing new transcriptional activities that lead within a few hours to the accumulation of heat shock proteins (Hsps), heat shock activates within minutes the major signaling transduction...Full Text Available

2002-04-01

266

Reaction pathways of the dissociation of methylal: A DFT study

Redd1, a recently discovered stress-response gene, is regulated by hypoxia via hypoxia-inducible factor 1 (HIF-1) and by DNA damage via p53/p63; however, the signaling pathway by which its expression is induced by hypoxia has not been elucidated. We demonstrated that the up-regulation of Redd1 transcription by hypoxia and high cell density (HCD) depends on cooperation between Sp1 and HIF-1#alpha# downstream of the PI3K/Akt pathway.

2006-05-25

267

Overview of macroautophagy regulation in mammalian cells

Schemata for modelling combustion processes do not yet include reaction rates for oxygenated fuels like methylal (DMM) which is considered as an additive or replacement for diesel due to its low sooting propensity. Density functional theory (DFT) studies of the possible reaction pathways for different dissociation steps of methylal are presented. Cleavage of a hydrogen bond to the methoxy group or the central carbon atom were simulated at the BLYP/6-311++G{sup **} level of theory. The results are compared to the experiment when dissociating and/or ionising DMM with femtosecond pulses. (author) 1 fig., 1 tab., 1 ref.

1999-08-01

268

British Library Electronic Table of Contents (United Kingdom)

Macroautophagy is a multistep, vacuolar, degradation pathway terminating in the lysosomal compartment, and it is of fundamental importance in tissue homeostasis. In this review, we consider macroautophagy in the light of recent advances in our understanding of the formation of autophagosomes, which are double-membrane-bound vacuoles that sequester cytoplasmic cargos and deliver them to lysosomes. In most cases, this final step is preceded by a maturation step during which autophagosomes interact with the endocytic pathway. The discovery of AuTophaGy-related genes has greatly increased our knowledge about the mechanism responsible for autophagosome formation, and there has also been progress in the understanding of molecular aspects of autophagosome maturation. Finally, the regulation of au...

2010-01-01

269

Honokiol-mediated inhibition of PI3K/mTOR pathway: a potential strategy to overcome immunoresistance in glioma, breast, and prostate carcinoma without impacting T cell function.

Aquatic pathways model to predict the fate of phenolic compounds

Inhibition of the phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) pathway is an appealing method for decreasing the immunoresistance and augmenting T cell-mediated immunotherapy. A major impediment to this strategy is the impact of conventional PI3K/mTOR pathway inhibitors on T cell function. In particular, rapamycin, is a well-known immunosuppressant that can decrease the activity of the PI3K/mTOR pathway in tumor cells, but also has a profound inhibitory effect on T cells. Here we show that Honokiol, a natural dietary product isolated from an extract of seed cones from Magnolia grandiflora, can decrease PI3K/mTOR pathway-mediated immunoresistance of glioma, breast and prostate cancer cell lines, without affecting critical proinflammatory T cell functions. Specifically, we show that at doses sufficient to down-regulate levels of phospho-S6 and the negative immune regulator B7-H1 ...

270

Upper limb dysfunction following selective neck dissection: A retrospective questionnaire study

Organic materials released from energy-related activities could affect human health and the environment. To better assess possible impacts, we developed a model to predict the fate of spills or discharges of pollutants into flowing or static bodies of fresh water. A computer code, Aquatic Pathways Model (APM), was written to implement the model. The computer programs use compartmental analysis to simulate aquatic ecosystems. The APM estimates the concentrations of chemicals in fish tissue, water and sediment, and is therefore useful for assessing exposure to humans through aquatic pathways. The APM will consider any aquatic pathway for which the user has transport data. Additionally, APM will estimate transport rates from physical and chemical properties of chemicals between several key compartments. The major pathways considered are biodegradation, fish and sediment uptake, photolysis, and evaporation. ...

1983-04-01

271

British Library Electronic Table of Contents (United Kingdom)

Background. To determine total upper limb function following selective neck dissection over a mean follow-up of 1.6 years. Methods. A retrospective questionnaire study in a tertiary head and neck surgical unit. One hundred forty-eight patients who underwent selective neck dissection for head and neck cancer from January 2000 to December 2005 were invited to participate. The main outcome measure was ipsilateral upper limb dysfunction as measured by the Disability of Arm, Shoulder and Hand (DASH) questionnaire. Results. Sixty-five patients responded to the invitation to join the study from 148 invited. Despite accessory nerve conserving surgery for all the selective neck dissections studied, 23% reported no upper limb dysfunction, 54% reported mild upper limb dysfunction, 15% reported modera...

2009-01-01

272

Tunneling magnetoresistance from a symmetry filtering effect

The Triton project -- A North Sea subsea challenge

This paper provides a brief overview of the young, but rapidly growing field of spintronics. Its primary objective is to explain how as electrons tunnel through simple insulators such as MgO, wavefunctions of certain symmetries are preferentially transmitted. This symmetry filtering property can be converted into a spin-filtering property if the insulator is joined epitaxially to a ferromagnetic electrode with the same two-dimensional symmetry parallel to the interface. A second requirement of the ferromagnetic electrodes is that a wavefunction with the preferred symmetry exists in one of the two spin channels but not in the other. These requirements are satisfied for electrons traveling perpendicular to the interface for Fe-MgO-Fe tunnel barriers. This leads to a large change in the resistance when the magnetic moment of one of the electrodes is rotated relative to those of the other electrode. This large tunneling magnetoresistance effect is being used as the ...

2008-04-01

273

TIG of Reduced Activation Ferrite/Martensitic Steel for the Korean ITER-TBM

Three companies--Amerada Hess Ltd., Shell Expro (a 50/50 joint partnership between Shell and Esso) and Texaco--have joined forces in a project that will combine their expertise. The Triton project will allow three fields (Bittern, Guillemot West and Gullemot Northwest) to be developed simultaneously using subsea technology, with the wellheads on the seafloor and 68 miles (110 km) of flowlines taking oil and gas produced from the fields to a central floating production storage and offloading (FPSO) vessel. These fields are located in the central area of the North Sea, about 118 miles from Aberdeen in 295 ft of water. The paper discusses the development of the fields, subsea technology, technical challenges, laying the pipeline, and project completion.

1998-11-01

274

Prevalence and incidence of depressive and anxious symptoms in couples undergoing assisted reproductive treatment in an Italian infertility department

Test Blanket Modules (TBM) will be tested in ITER to verify the capability of tritium breeding and recovery and the extraction of thermal energy suitable for the production of electricity. A Helium Cooled Solid Breeder (HCSB) TBM has been developed in Korea to accomplish these goals. Reduced Activation Ferritic/Martensitic (RAFM) steel has been chosen as the primary candidate structural material for Korean TBM. Due to the complexity of the First wall (FW) and Side wall (SW), it is necessary to develop various joining technologies, such as Hot Isostatic Pressing (HIP), Electron Beam Welding (EBW) and Tungsten Inert Gas (TIG) welding, for the successful fabrication of TBM. In this study, the mechanical properties of TIG welded RAFM steel were investigated. Various mechanical tests of TIG-welded RAFM steel were performed to obtain the optimized TIG welding process for RAFM steel

2010-10-01

275

British Library Electronic Table of Contents (United Kingdom)

Objective: We have conducted a longitudinal observational study in order to evaluate the prevalence and the incidence of depressive and anxious symptoms in women and men seeking infertility treatment and to analyze associated factors or risk factors for these kinds of disorders. Study design: A total of 1000 consecutive couples that visited our center for the first time were asked to join this study. Depressive and anxious symptoms were assessed with self-rating Zung Depression Scale (ZDS) and Zung Anxiety Scale (ZAS) questionnaires. A second assessment was planned at the time of b HCG dosage (or at the moment of cycle suspension). A standard questionnaire was used to investigate socio-demographic information and the psychological aspects of couples undergoing in vitro fertilization (IVF) ...

2011-01-01

276

Preparation of reactor tube by welding a porous membrane with a non-porous ceramic tube

Natural gas utilization as fuel in urban rail transport; Utilizacao do gas natural como combustivel no transporte ferroviario urbano

In the course of designing a catalytic porous membrane reactor for experimental studies, both inside and outside of the non-reaction zones as well as the two ends of the membrane need to be completely sealed to ensure that there is no flow across the membrane in the non-reaction zone. Experiments show that up to 50% of the total flow across the membrane may be contributed by the axial flow along the wall of the non-reaction zones if only one side of the membrane is sealed. Another problem that cannot be solved by sealing is the capillary flow of the catalyst along the tube wall into the non-reaction zones when the catalyst is doped on the membrane. One of the best ways to avoid this axial flow of catalyst would be to use non-porous tubes in the non-reaction zones and join them with the porous membrane tube. In doing so, the cost of the membrane reactor could be reduced simply because shorter membrane tube is needed.

1994-12-31

277

Japanese will join West Germany in funding coal-liquefaction project

The majority of Brazilian big cities served by conventional railroad systems with routes starting in the center of the URBIS, destinate them the long distances transport of passengers and cargo. Actually, these systems are being transformed to become commuter trains which join a great capacity of transportation to a much lower costs of implantation than subway ones. The most important characteristic of this train, when talking about energy consumption, is the possibility of using different kinds of explosion engines from three cycles: Diesel, mixed (Diesel + Natural Gas), and Otto moved by natural gas, besides the traditional electric traction. The use of natural gas in Otto cycle engines shows itself competitive from the point of view of investments, operational costs and environmental preservation. (author). 10 refs., 1 fig

1995-12-31

278

Interfacial ultrafine-grained structures on aluminum alloy 6061 joint and copper alloy 110 joint fabricated by magnetic pulse welding

The funding for a coal-liquefaction demonstration plant near Morgantown, W.Va., appears more certain since Japan has committed $175 million toward the project. West Germany has already signed a memorandum of understanding to contribute 25% of the expected $700 million cost. West Virginia Governor J. Rockefeller has said that he feels sure the Carter Administration will approve the project since half the money is assured. The solvent-refined-coal (SRC) demonstration program began in July 1978 with the award of two separate multiphased contracts for development of a solid process, SRC-I, and a liquid process, SRC-II. The US Department of Energy is expected to choose one of the projects for detailed design and construction by the end of fiscal 1979.

1979-05-16

279

British Library Electronic Table of Contents (United Kingdom)

Magnetic pulse welding is a solid state impact welding process, similar to explosive welding, which produces metallurgical bond by oblique high-speed impact between two metal bodies. This violent impact removes the metal surface oxide layers and then joins the two atomic level clean metal surfaces together by the incidental compression pressure. The impact velocity is at 200?400?m/s and the being welded metal surface undergoes severe plastic deformation with strain rate in the order of 106?107?s?1. The ultrafine-grained structure was observed on the welded interface. This article studied two types of similar material lap joint interfaces and the base metals were aluminum alloy 6061 and copper alloy 110. Nano-indentation testing shows that the welded interfaces have significantly greater ha...

2010-01-01

280

Electromagnetic forming - a potentially viable technique for accelerator technology

Comparative thermal cyclic test of different beryllium grades previously subjected to simulated disruption loads

Modern day accelerator development encompasses a myriad technologies required for their diverse needs. Whereas RF, high voltage, vacuum, cryogenics etc., technologies meet their functional requirements, high finish lapping processes, ceramic-metal joining, oven brazing, spark erosion or wire cutting etc., are a must to meet their fabrication requirements. Electromagnetic (EM) forming technique falls in the latter category and is developed as a special technology. It is currently catering to the development as a nuclear reactor technology, but has the potential to meet accelerator requirements too. This paper highlights the general principle of its working, simple design guidelines, advantages, and suggests some specific areas where this could benefit accelerator technologies

2003-02-03

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281

Benchmarking Declarative Approximate Selection Predicates

Considering beryllium as plasma facing armour this paper presents recent results obtained in Russia. A special process of joining beryllium to a Cu-alloy material structure is described and recent results of thermal cycling tests of such joints are presented. Summarizing the results, the authors show that a Cu-alloy heat sink structure armoured with beryllium can survive high heat fluxes ({>=}10 MW/m{sup 2}) during 1000 heating/cooling cycles without serious damage to the armour material and its joint. The principal feasibility of thermal cycling of beryllium grades and their joints directly in the core of a nuclear reactor is demonstrated and the main results of this test are presented. The paper also describes the thermal cycling of different beryllium grades having cracks initiated by previously applied high heat loads simulating plasma disruptions. (orig.)

1999-11-01

282

Advances in feedstock recycling offer help with plastic waste

Declarative data quality has been an active research topic. The fundamental principle behind a declarative approach to data quality is the use of declarative statements to realize data quality primitives on top of any relational data source. A primary advantage of such an approach is the ease of use and integration with existing applications. Several similarity predicates have been proposed in the past for common quality primitives (approximate selections, joins, etc.) and have been fully expressed using declarative SQL statements. In this thesis, new similarity predicates are proposed along with their declarative realization, based on notions of probabilistic information retrieval. Then, full declarative specifications of previously proposed similarity predicates in the literature are presented, grouped into classes according to their primary characteristics. Finally, a thorough performance and accuracy study comparing a large number of similarity predicates for ...

2009-01-01

283

An idea whose time has come takes center stage in London this week when BP Chemicals announces details of a consortium of chemical companies joining it in a new recycling project. In the project, which BP has been working on since 1989, waste plastic will be depolymerized to chemical feedstocks, via technology variously called feedstock or chemical recycling, polymer cracking, or tertiary recycling. BP's effort is one of the first to emerge from the research and pilot-plant stages that are committed to actual feedstock recycling of mixed polyolefins and other plastics. But it is only one of the many industry efforts under way to cope with the job of dealing with postconsumer plastics.

1993-10-04

284

A connecting coupling

Diverter/bop system and method for a bottom supported offshore drilling rig

The flexible, insulated, single strand cables are electrically connected with a cylindrical polar tip (PN) by means of cylindrical and conical shafts for the polar tips, which enter the faces of the divided, multiwire strand, clamped by tension half couplings. The flat ends of the polar tips being joined are positioned in two concentric mandrel bushings, an internal fixed one and an external, axially movable bushing (PV). The internal bushing is rigidly attached to the end of the left polar tip and equipped with three or four rounded, radial openings, whose diameter is determined by the external diameter of the locking device hinges (ShF) of the connecting couplings. The right polar tip is equipped with an annular channel of trapezoidal section into which the locking device hinges enter. The external movable bushing on the right side has a conical turning and on the left, a cylindrical into which the cylindrical spring which holds the movable bushing in the extreme ...

1981-06-05

285

Development of a numerical methodology to simulate the roller expansion forming process

A system is described adapted for alternative use as a diverter or a blowout preventer for a bottom supported drilling rig and adapted for connection to a permanent housing attached to rig structural members beneath a drilling rig rotary table, the permanent housing having an outlet connectable to a rig fluid system flow line. The system consists of: a fluid flow controller having a controller housing with a lower cylindrical opening and an upper cylindrical opening and a vertical path therebetween and a first outlet passage and a second outlet passage provided in its wall, a packing element disposed within the controller housing, and annular piston means adapted for moving from a first position to a second position, whereby in the first position the piston means wall prevents interior fluid from communicating with the outlet passages in the controller housing wall and in the second position the piston means wall allows fluid communication of interior fluid with the outlet passages and ...

1986-07-01

286

Large scintillation cells for high sensitivity radon concentration measurements

A distinguishing design feature of CANDU nuclear reactors is the use of horizontal fuel channels housed in a horizontal vessel called a calandria, which is made of stainless steel 304L. Each channel consists of a Zr-2.5%Nb alloy pressure tube and an externally concentric Zr-2 calandria tube. The calandria tubes are joined to the end plates (tubesheets) of the calandria vessel by joints formed by roller expansion. The bores in the tubesheets are grooved. Roller expanded joints provide a cost effective means of joining dissimilar materials, require minimal space and no maintenance. The quality of these roller expanded joints is important from a sealing, strength and stress corrosion point of view. The roller expansion process consists of expanding the calandria tubes to deform them plastically against the bores and into the grooves of the tubesheets. Therefore, understanding the effect of the number, geometry and the pitch of the grooves on the ...

2006-04-03

287

Large scintillation cells for high sensitivity radon concentration measurements

Methods for improving the sensitivity of scintillation cells for radon concentration measurements were studied with emphasis on improving light collection efficiency. This allows the length and hence the volume of the cell to be increased. Variables studied were choice of scintillator material, its method of application and thickness, length of cell, cell material, type and configuration of reflectors, choice of photomultipliers, and factors affecting background. Response from various areas of the cell surface was studied with an alpha source and with radon filling. Coating the window with phosphor was found to be counter-productive. The optimum results obtained were with the inside of the cell (other than the window) covered with a thick layer of ZnS(Ag), or with a thick layer of reflective material coated with a thin layer of phosphor. With it, a 10 cm diameter plexiglass cell can be extended to at least 50 cm length without difficulty from ...

1983-07-01

288

Importance of health and environment as quality traits in the buying decision of organic products

Methods for improving the sensitivity of scintillation cells for radon concentration measurements were studied with emphasis on improving light collection efficiency. This allows the length and hence the volume of the cell to be increased. Variables studied were choice of scintillator material, its method of application and thickness, length of cell, cell material, type and configuration of reflectors, choice of photomultipliers, and factors affecting background. Response from various areas of the cell surface was studied with an alphy source and with radon filling. Coating the window with phosphor was found to be counter-productive. The optimum results obtained were with the inside of the cell (other than the window) covered with a thick layer of ZnS(Ag), or with a thick layer of reflective material coated with a thin layer of phosphor. With it, a 10 cm diameter plexiglass cell can be extended to at least 50 cm length without difficulty from ...

289

British Library Electronic Table of Contents (United Kingdom)

This paper aims to explore consumer preference for fresh vegetables labelled as organic in combination with health and environment related quality traits. The study decomposes organic farming into its main quality aspects and measures consumers' preference structure for organic, in general, and for specific organic quality traits in particular. By means of stated choice preference modelling, the following hypotheses are tested: consumers prefer health over environment related quality traits; the organic label plays a significant role in consumers' choice for organic products; organic farming is perceived as healthier and more environmentally friendly than conventional farming; purchase intention is mainly driven by health related quality traits; both health and environmental concerns influ...

2009-01-01

290

How do Black Holes Spin in Chern-Simons Modified Gravity?

Credit rationing in rural credit markets of India

No Kerr-like exact solution has yet been found in Chern-Simons modified gravity. Intrigued by this absence, we study stationary and axisymmetric metrics that could represent the exterior field of spinning black holes. For the standard choice of the background scalar, the modified field equations decouple into the Einstein equations and additional constraints. These constraints eliminate essentially all solutions except for Schwarzschild. For non-canonical choices of the background scalar, we find several exact solutions of the modified field equations, including mathematical black holes and pp-waves. We show that the ultrarelativistically boosted Kerr metric can satisfy the modified field equations, and we argue that physical spinning black holes may exist in Chern-Simons modified gravity only if the metric breaks stationarity, axisymmetry or energy-momentum conservation.

2007-01-01

291

British Library Electronic Table of Contents (United Kingdom)

This article analyses the prevalent situation of the formal Financial Institutions (FIs) in rural India using data from National Sample Survey 54th Round (January-June, 1998). We use sample selectivity model to examine the sanction of the loan by the FIs as a two-stage process. We model the choice of the household's credit requirement using an unordered choice model, namely, a multinomial logit model. Our results reveal that the rural households are considerably credit constrained. The households who do not have an account in a FI have a lower chance of obtaining the loan and households who are credit constrained have relatively lower land holding and they do not possess livestock. Households who borrow for nonfarm purpose exhibit a lower chance of obtaining credit compared to those househ...

2012-01-01

292

Cosmic-ray antiprotons, positrons, and gamma rays from halo dark matter annihilation

An effective approach to the problem of time: general features and examples

The subject of cosmic ray antiproton production is reexamined by considering other choices for the nature of the Majorana fermion chi other than the photino considered in a previous article. The calculations are extended to include cosmic-ray positrons and cosmic gamma rays as annihilation products. Taking chi to be a generic higgsino or simply a heavy Majorana neutrino with standard couplings to the Z-zero boson allows the previous interpretation of the cosmic antiproton data to be maintained. In this case also, the annihilation cross section can be calculated independently of unknown particle physics parameters. Whereas the relic density of photinos with the choice of parameters in the previous paper turned out to be only a few percent of the closure density, the corresponding value for Omega in the generic higgsino or Majorana case is about 0.2, in excellent agreement with the value associated with galaxies and one which is sufficient to ...

1988-02-01

293

Transcriptome analysis reveals salt-stress-regulated biological processes and key pathways in roots of cotton (Gossypium hirsutum L.).

The effective approach to quantum dynamics allows a reformulation of the Dirac quantization procedure for constrained systems in terms of an infinite-dimensional constrained system of classical type. For semiclassical approximations, the quantum constrained system can be truncated to finite size and solved by the reduced phase space or gauge-fixing methods. In particular, the classical feasibility of local internal times is directly generalized to quantum systems, overcoming the main difficulties associated with the general problem of time in the semiclassical realm. The key features of local internal times and the procedure of patching global solutions using overlapping intervals of local internal times are described and illustrated by two quantum mechanical examples. The choice of time is tantamount to a choice of gauge at the effective level and changing the clock is, therefore, equivalent to a gauge transformation. This article complements ...

2010-01-01

294

Residence time probability analysis of sulfur concentrations at Grand Canyon National Park

High salinity is one of the main factors limiting cotton growth and productivity. The genes that regulate salt stress in TM-1 upland cotton were monitored using microarray and real-time PCR (RT-PCR) with samples taken from roots. Microarray analysis showed that 1503 probe sets were up-regulated and 1490 probe sets were down-regulated in plants exposed for 3h to 100mM NaCl, and RT-PCR analysis validated 42 relevant/related genes. The distribution of enriched gene ontology terms showed such important processes as the response to water stress and pathways of hormone metabolism and signal transduction were induced by the NaCl treatment. Some key regulatory gene families involved in abiotic and biotic sources of stress such as WRKY, ERF, and JAZ were differentially expressed. Our transcriptome analysis might provide some useful insights into salt-mediated signal transduction pathways in cotton and offer a number of candidate genes as potential ...

2011-04-30

295

Land And Water Use Characteristics And Human Health Input Parameters For Use In Environmental Dosimetry And Risk Assessments At The Savannah River Site

A statistical method is developed to determine the locations of major pollutant sources affecting a distant downwind receptor, provided that air trajectories can be estimated. Probability density functions are estimated which indicate the overall residence time of air parcels over a given geographic region as they travel toward a receptor and residence time for the case of high pollutant concentrations at the receptor. These functions are used to estimate a conditional probability function which indicates the potential for a source region to contribute to high air pollution concentrations. Finally, a source contribution function is formulated to indicate the relative contribution of different source regions to high concentrations at the receptor. The method is tested using data collected at Grand Canyon National Park in 1980. The dominant pathway for air masses arriving at Grand Canyon during this period was southern California. A lesser ...

1985-01-01

296

Effects of Acetate Competition, pH and Soil Structure on the Rates and Pathways of Methane Formation in Tropical Rain Forest Soils

Operations at the Savannah River Site (SRS) result in releases of small amounts of radioactive materials to the atmosphere and to the Savannah River. For regulatory compliance purposes, potential offsite radiological doses are estimated annually using computer models that follow U.S. Nuclear Regulatory Commission (NRC) Regulatory Guides. Within the regulatory guides, default values are provided for many of the dose model parameters but the use of site-specific values by the applicant is encouraged. A detailed survey of land and water use parameters was conducted in 1991 and is being updated here. These parameters include local characteristics of meat, milk and vegetable production; river recreational activities; and meat, milk and vegetable consumption rates as well as other human usage parameters required in the SRS dosimetry models. In addition, the preferred elemental bioaccumulation factors and transfer factors to be used in human health exposure calculations at SRS are documented. ...

297

Translocation of labelled sucrose: A student exercise

The C isotopic composition of CH4 emissions are strongly influenced by the pathway of CH4 formation. Contrary to data from other freshwater systems, soil gas and surface flux measurements made in the tropical rain forests of Puerto Rico strongly suggest that CH4 produced in these environments was derived from CO2 reduction, rather than from acetate consumption. This study explored the effects of bacterial competition for acetate, pH, and soil structure on the pathways of CH4 formation in tropical rain forest soils. Our goal was to test two principal hypotheses: (1) ferric iron-reducing bacteria out-competed methanogens for acetate, resulting in greater CO2 reduction rather than aceticlastic methanogenesis, and (2) the low pH of tropical rain forest soils favors CO2 reduction rather than aceticlastic methanogenesis. In addition, this study also investigated the effect of destroying soil aggregate structure on the pathways ...

2004-12-01

298

Targeting the kynurenine pathway as a potential strategy to prevent and treat Alzheimer's disease

Photosynthetic carbohydrates from the leaves are exported through the phloem to growing tips, roots, flowers and fruits. If sucrose labelled with {sup 14}C is applied to the leaves of bean plants, the pathway for sugar movement may be readily observed by autoradiography. Students apply the labelled sucrose during class time and return the next day to press their plants. During the next class, the pressed and dried plants are placed against X-ray film and left in the dark for four weeks. the film is then developed, examined for presence of label and compared to the pressed plants. Source to sink movement is clearly illustrated and information about the mechanism of phloem transport and loading is gained through experimental treatments, which include blocking the phloem pathway and inhibiting energy production.

1990-05-01

299

British Library Electronic Table of Contents (United Kingdom)

Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the elderly accounting for the vast majority of dementia. Recently, many studies have implicated the role of inflammatory response, especially neuroinflammatory response in the development and progression of AD. However, the underlying mechanism of how inflammatory response induces AD is unknown. Kynurenine pathway is a major route of the amino acid tryptophan catabolism, resulting in the production of nicotine adenine dinucleotide and other neuroactive intermediates: quinolinic acid (QA) and kynurenic acid (KA). QA exerts different toxic effects, including over-activation of N-methyl-d-aspartate (NMDA) receptor and excitotoxicity, synaptic dysfunction and neuronal death. On the other hand, KA is identified as the only...

2011-01-01

300

SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway

British Library Electronic Table of Contents (United Kingdom)

Background and purpose: The aims of this study were to investigate the anti-cancer activity of SZ-685C, an anthracycline analogue isolated from marine-derived mangrove endophytic fungi, and to explore the molecular mechanisms underlying such activity. Experimental approach: The effect of SZ-685C on the viability of cancer cell lines was investigated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. SZ-685C-induced apoptosis was assessed by Annexin V-fluorescein isothiocyanate/propidium iodide staining, terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling assay and analysis of caspase activation. The effect of SZ-685C on the Akt/FOXO pathway was studied using Western blotting analysis, and the in vivo anti-tumour efficacy was examined in ...

2010-01-01

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301

Pore structure of volcanic clasts: Measurements of permeability and electrical conductivity

British Library Electronic Table of Contents (United Kingdom)

The pore structure of volcanic clasts is examined using measurements of porosity, permeability, and electrical properties. Permeability varies by several orders of magnitude among volcanic clasts and does not depend solely upon porosity. Electrical property measurements of saturated volcanic samples illustrate the influence of pathway tortuosity and pore shape on permeability. For equivalent eruption conditions, silicic samples show higher tortuosities, smaller vesicle sizes, and lower permeabilities than mafic samples. These differences are largely due to variations in vesiculation and crystallization history. Differences between explosive and effusive samples reflect the relative ability of bubbles to form and maintain connected pathways during bubble expansion and collapse. Isotropic sa...

2009-01-01

302

Pathways for implementing REDD+. Experiences from carbon markets and communities

Molecular biology of the renin-angiotensin system

This issue of Carbon Market Perspectives on 'Pathways for implementing REDD+: Experience from carbon markets and communities' discusses the role of carbon markets in scaling up investments for REDD+ in developing countries. Nine articles authored by experienced negotiators on REDD+, carbon market actors, project developers and other leading experts share experiences and make suggestions on the key elements of a future international REDD+ regime: Architecture and underlying principles, measuring, reporting and verification (MRV), private-sector involvement, the rights of indigenous people and local communities, biodiversity conservation and environmental integrity. The articles are grouped under three main topics: the lessons of existing REDD+ projects; the future REDD+ regime and the role of carbon markets; and experiences and ideas about the involvement of indigenous people and local communities. (LN)

2011-07-01

303

Mitochondria-localized NAD biosynthesis by nicotinamide mononucleotide adenylyltransferase in Jerusalem artichoke (Helianthus tuberosus L.) heterotrophic tissues

This paper reviews the molecular biology of the renin-angiotensin system. The renin gene structure is analyzed in detail, including an examination of the putative regulatory regions. The combined action of these regulatory sequences would result in the complex, tissue-specific expression and regulation observed in vivo. The expression of the tissue renin-angiotensin systems, which may have important physiological functions, is also described. In addition, the pathway of renin biosynthesis and secretion is reviewed. This includes speculation on the fate of circulating prorenin and the physiological role of multiple renin forms and secretory pathways. The molecular approaches described in this paper have greatly advanced our knowledge of the biology of the renin-angiotensin system. Future studies using these and other approaches should provide further insight into this complex system.

1988-10-01

304

British Library Electronic Table of Contents (United Kingdom)

Current studies in plants suggest that the content of the coenzyme NAD is variable and potentially important in determining cell fate. In cases that implicate NAD consumption, re-synthesis must occur to maintain dinucleotide pools. Despite information on the pathways involved in NAD synthesis in plants, the existence of a mitochondrial nicotinamide mononucleotide adenylyltransferase (NMNAT) activity which catalyses NAD synthesis from nicotinamide mononucleotide (NMN) and ATP has not been reported. To verify the latter assumed pathway, experiments with purified and bioenergetically active mitochondria prepared from tubers of Jerusalem artichoke (Helianthus tuberosus L.) were performed. To determine whether NAD biosynthesis might occur, NMN was added to Jerusalem artichoke mitochondria (JAM)...

2011-01-01

305

Knowledge-Based Identification of the ERK2/STAT3 Signal Pathway as a Therapeutic Target for Type 2 Diabetes and Drug Discovery

British Library Electronic Table of Contents (United Kingdom)

Many existing agents for diabetes therapy are unable to restore or maintain normal glucose homeostasis or prevent the eventual emergence of hyperglycemia-related complication. Therefore, agents based on novel mechanisms are sought to complement and extend the current therapeutic approaches. Based on the initial paper research, we focused on active STAT3 as an attractive pharmacological target for type 2 diabetes. The subsequent text mining with a unique query to identify suppressors but not activators of STAT3 revealed the ERK2/STAT3 pathway as a novel diabetes target. The description of ERK2 inhibitors as diabetes target had not been found in our text mining research at present. The mechanism-based peptide inhibitor for ERK2 was identified using the knowledge of the KIM sequence, which ha...

2011-01-01

306

Experimental bovine trypanosomiasis. Changes in serum immunoglobulins, complement and complement components in infected animals.

Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli

In three calves experimentally infected with Trypanosoma congolense the amounts of IgG1 and IgG2 were little changed and similar to those of normal animals. IgM increased in amount early in the infection and the amount of the increase appeared related to the parasite burden. The amounts of IgA and IgE were both much decreased and this also appeared related to the numbers of parasites in the blood. There was a decrease in the amounts of total haemolytic complement and complement components C1, C1q and C3 in the infected calves. Furthermore the amounts of properdin fluctuated with the cyclical changes in numbers of T. congolense parasites in the individual calves. No significant change in the amount of C8 was observed. It is considered that activation of both the alternative and the classical complement pathways occurs in trypanosome infected animals but that neither pathway goes to its terminal stages.

1978-11-01

307

British Library Electronic Table of Contents (United Kingdom)

2-methylpropan-1-ol (isobutanol) is a leading candidate biofuel for the replacement or supplementation of current fossil fuels. Recent work has demonstrated glucose to isobutanol conversion through a modified amino acid pathway in a recombinant organism. Although anaerobic conditions are required for an economically competitive process, only aerobic isobutanol production has been feasible due to an imbalance in cofactor utilization. Two of the pathway enzymes, ketol-acid reductoisomerase and alcohol dehydrogenase, require nicotinamide dinucleotide phosphate (NADPH); glycolysis, however, produces only nicotinamide dinucleotide (NADH). Here, we compare two solutions to this imbalance problem: (1) over-expression of pyridine nucleotide transhydrogenase PntAB and (2) construction of an NADH-de...

2011-01-01

308

Chronic sympathetic activation promotes downregulation of ?-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction

British Library Electronic Table of Contents (United Kingdom)

It is uncertain if downregulation of ?-adrenoceptor signaling pathway is promoted by an enhanced adrenergic tone at an early stage of cardiac disease, or it develops secondary to detrimental local myocardial changes in advanced heart failure. We examined the integrity of ?-adrenoceptor signaling pathway upon chronic infusion of isoproterenol, a ?-adrenoceptor agonist, at a dose producing no structural left ventricular (LV) remodeling and systolic dysfunction. Subcutaneous isoproterenol infusion (400??g?kg?1?h?1 over 16?days) to guinea pigs using osmotic minipumps produced no change in cardiac weights, LV internal dimensions, myocyte cross-sectional area, extent of interstitial fibrosis, and basal contractile function. Isolated, perfused heart preparations from isoproterenol-treated guinea ...

2011-01-01

309

A phase II trial of sorafenib in first-line metastatic urothelial cancer: a study of the PMH Phase II Consortium

British Library Electronic Table of Contents (United Kingdom)

Summary Background Sorafenib is an oral multikinase inhibitor that blocks cell proliferation via the ERK pathway and angiogenesis via the VEGF pathway. This phase II trial was conducted to determine the efficacy and tolerability of sorafenib for the treatment of patients with metastatic urothelial cancer (UC) who had not had prior chemotherapy for advanced disease. Patients and Methods Seventeen chemo-na?ve UC patients with adequate performance status and organ function were treated with sorafenib 400?mg twice daily on a continuous basis until progression or unacceptable toxicity. The primary endpoint was objective tumor response rate as measured by RECIST criteria. Secondary endpoints included rate of prolonged stable disease (>3?months), time to progression, median and 1?yr survival and ...

2011-01-01

310

A computer program for rapid calculation of internal committed effective dose through inhalation and ingestion pathways under radiological emergency

6-Substituted imidazo[1,2-a]pyridines: Synthesis and biological activity against colon cancer cell lines HT-29 and Caco-2

Objective: To establish a computer program for rapid calculation of internal committed effective close through inhalation and ingestion pathways under radiological emergency. Methods: Visual Basic 6.0 is used to compile the generic procedures of internal committed effective dose by inhalation and ingestion in IAEA-TECDOC-1162, Generic Procedures for Assessment and Response during a Radiological Emergency. Results: The assessment methodology of internal committed effective dose by inhalation and ingestion under radiological emergency in the report IAEA-TECDOC-1162 can be coded into a computer program. Conclusions: This research provides a rapid method of assessment for internal committed effective dose by inhalation and ingestion under radiological emergency, and it may provide needed dosimetry data for treatment under emergency response. (authors)

2008-08-01

311

British Library Electronic Table of Contents (United Kingdom)

A range of 6-substituted imidazo[1,2-a]pyridines were synthesized using a multicomponent coupling reaction. Most of these compounds were found to exhibit excellent activity against the colon cancer cell lines HT-29 and Caco-2, whilst not showing significant toxicity against white blood cells. Our studies have shown that the proteolytic phase of apoptosis was initiated 2 h after treatment with these imidazo-[1,2-a]pyridines. The data suggests that the imidazo[1,2-a]pyridine-induced cell death in HT-29 and Caco-2 cells is mediated via pathway(s) that include the release of cytochrome c from the mitochondria to the cytosol and the activation of caspase 3 and caspase 8.

2011-01-01

312

Themis solar receiver

The underdog should always fire the first salvo against Brazil

The conception of a solar receiver intended to equip a tower power-station has to combine multiple requirements: very highly concentrated solar flux, unsteady in time and space; necessity to obtain a high efficiency; respect of the physical limits of the materials and of the fluid. The description of Themis solar receiver and of its operation is preceded by considerations which have led to the choice of the cavity, of the fluid and of its circulation.

1982-01-01

313

British Library Electronic Table of Contents (United Kingdom)

A popular myth in football (soccer) that it is unwise tactically to score early against Brazil is busted using data from 1993 to 2010. This result provides further evidence about the choice of timing of effort exertion by an underdog in a finite-length industry contest against a more favoured opponent.

2012-01-01

314

The role of imaging in the choice of correct treatment of unstable thoraco-lumbar fractures

The results of treatment of localized Ewing's sarcoma and reticulosarcoma in pediatric patients

The concept of unstable burst fracture has been discussed since over 50 years and this injury has received much attention in the literature as regards its radiological diagnosis and clinical treatment. The purpose of this article is to review the way we use imaging to diagnose the injury and to guide treatment.

2006-09-01

315

Studies of off-shell amplitudes in string theory

The results of treatment of 53 cases of pediatric localized Ewing's sarcoma and bone reticulosarcoma were analized. Chemoradiotherapy is a procerdure of choice in bone marrow sarcoma treatment: while overall five-year survival was 28.4#+-#6.2%, it was as high as 64.9% in cases of combined treatment (total focal dose of at least 50 Gy+polychemotherapy). Two cases of osteo- and chondrosarcoma development in exposed bone are described.

316

Solar-powered humidification dehumidification desalination system

Off-shell amplitudes for the open bosonic string and the closed spinning string are considered. Due to the presence of corners on the open string world sheet, strict Weyl invariance is broken. A consistent gauge-fixing procedure to treat this anomaly is described. Factorization of amplitudes with one or two off-shell strings and any number of on-shell tachyons is established. An attempt is made to construct a propagator for the spinning string. The inherent ambiguities in the choice of boundary conditions for the fermionic coordinates are outlined.

1989-01-01

317

Role of CT in TNM staging of laryngeal and hypopharyngeal tumors

Presented are some preliminary studies made in preparation for the design of a solar powered loop for desalination by humidification - dehumidification process. The studies concentrated on the evaluation of different parameters affecting the performance of the combination of different components in such a loop in the hope of outlining the most decisive factors for the choice or design of solar collectors or heat source. The results presented relate to the performance of two of the most important components in a loop of such purpose, that is: the humidifying and the dehumidifying columns or stacks. 4 refs.

1980-01-01

318

Risk management and pricing: Enhancing customer choices

70 patients with squamouscell carcinoma of larynx and hypopharynx were examined by computed tomography; the TNM staging of tumors by CT, by endoscopy and by surgical operation was reviewed. CT proved to be reliable both to recognize the presence of neoplasms, with the exception of those very superficial, and their deep spreading to preepiglottic and paralaryngeal spaces, to the soft tissues of the neck and to the cartilages. Therefore CT is the examination of choice in laryngeal neoplasms staging, because it precisely completes the clinical and endoscopical informations.

1986-01-01

319

Religious groups have too much freedom to discriminate | Evan Harris | Comment is free | guardian.co.uk

As competition dramatically reshapes power markets, electric utilities strive to increase flexibility in their commitments and limit exposure to market risks. This paper provides an overview of a promising tool called option valuation which is useful for analyzing and managing risks. The paper demonstrates an application of these techniques for developing new pricing products tailored to meet customers` risk preference.

1996-03-01

320

Parahydrogen clusters: Numerical estimates and physical effects

... Wanting to help a charity is commendable but the main focus of generosity should be the people in front of you, not your choice of spiritual overlord - especially so if the group is being funded with money from taxpayers. Recommend? (44) Report abuse | Link ...

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

321

Optimal choice of cupola furnace nominal operating point

We study by means of Quantum Monte Carlo simulations based on the Worm Algorithm the low temperature (down to T = 0.05 K) properties of parahydrogen clusters comprising up to 40 molecules. Three different intermolecular interactions are employed: the Silvera-Goldman, the Buck and the Lennard-Jones potential. Despite important discrepancies observed in the numerical estimates of energy and superfluid fraction, the mechanism by which clusters melt at low T is independent of the particular choice of the potential, whose only effect is to alter the temperature scale.

2009-02-01

322

Marsden-Ratiu reduction and W_3"2 algebra

One of the main goals in the operation of a cupola furnace is to keep the molten iron properties within prescribed bounds while maintaining the most economical operation for the cupola. In this paper the authors present a procedure to obtain the nominal values for the manipulated process variables. The nominal values are calculated by solving a constrained nonlinear programming optimization problem. Two different optimization problems are discussed and examples for using the procedure are presented.

1998-08-01

323

Heating and hot water: the installations; Chauffage et eau chaude: les installations

The W_3"2 algebra is deduced by the Marsden-Ratiu reduction in the bi-Hamiltonian framework proposed by Magri et al and compared with the usual derivations via the Drinfeld-Sokolov formalism. It is observed that the choice of A in the first Poisson tensor must be different for W_3"2 algebra. (orig.).

1997-01-01

324

Guarantee outline of radiation hardening for satellite

This book brings recommendations and information on the choice and the operating of heating systems and domestic hot water production in order to better choose the house, to better use the heating and to preserve the environment. General notions on the different heating systems and their operating on the renewable energies used and the heating emitters offer advices for the purchase of a house. (A.L.B.)

2005-07-01

325

Geometrically relating momentum cut-off and dimensional regularization

The Guarantee Outline presents the technical demands of design and contents of assessment for radiation hardening in satellite engineering in China. It includes the basis of design in space environment of polar orbit, the contents of design for general radiation hardening, the requirements and assessments of the single-board computer, the requirements of design for circuits (including hardware and software), the choices and assessments for devices, and the primary stipulations for the requirements of design and assessments against the phenomenon of charge and discharge.

326

Evaluation of peripheral vascular disease by intravenous digital subtraction angiography with the Fuji computed radiography (FCR) system

The $\\beta$ function for a scalar field theory describes the dependence of the coupling constant on the renormalization mass scale. This dependence is affected by the choice of regularization scheme. I explicitly relate the $\\beta$-functions of momentum cut-off regularization and dimensional regularization on scalar field theories by a gauge transformation using the Hopf algebras of the Feynman diagrams of the theories.

2011-01-01

327

Evaluation of peripheral vascular disease by intravenous digital subtraction angiography with the Fuji computed radiography (FCR) system

Intravenous digital subtraction angiography using Fuji computed radiography system (FCR-DSA) was used to evaluate 57 preoperative patients with clinical manifestations of peripheral vascular disease of lower extremity. With its high contrast resolution and good special resolution, image of FCR-DSA could offer optimal information of vascular abnormality in lower extremity distal to midfoot for the diagnosis and the choice of management.

1987-03-01

328

Energy in Lebanon: holding the stakes to get best choices

Intravenous digital subtraction angiography using Fuji computed radiography system (FCR-DSA) was used to evaluate 57 preoperative patients with clinical manifestations of peripheral vascular disease of lower extremity. With its high contrast resolution and good special resolution, image of FCR-DSA could offer optimal information of vascular abnormality in lower extremity distal to midfoot for the diagnosis and the choice of management. (orig.).

1987-01-01

329

Determination of progesterone for reproduction control in cows using a /sup 3/H radioimmunoassay. 1. Methods and choice of testing samples

An overall review of status of energy in Lebanon is presented. Energy consumption and demand, in all sectors of economy, including renewable energy sources (biomass, solar energy, kerosene, gas oils...) are described, enhanced by figures and tables. Recommendations of energy development in Lebanon within national economic policy are formulated. 4 tabs.

330

Covariant open bosonic string field theory including the endpoint and middlepoint interaction

For verification of cow fertility a /sup 3/H radioimmunoassay of progesterone in milk and blood plasma was developed. It is of high specificity and accuracy as well. Extraction of progesterone from milk was facilitated by application of alcohol. Suggested differences in milk and plasma progesterone levels between pregnant and nonpregnant cows could be revealed.

1984-01-01

331

Comparison of ion chromatography and titrimetry for determination of sulfur in fuel oils

Extending the usual endpoint and midpoint interactions, we introduce numerous kinds of interactions, labelled by a parameter lambda and obtain a non-commutative and associative string field algebra by adding up all interactions. With this algebra we develop a covariant open bosonic string field theory, which reduces to Witten's open bosonic string field theory under a special string length choice.

1988-07-01

332

CT-guided percutaneous aspiration and drainage of postoperative abdominal fluid collections

A comparison was made of Parr bomb ion chromatographic and titrimetric methods to determine sulfur in fuel oils. The two methods are comparable in precision and accuracy. When rapid sulfur determination in a number of samples is desired, the titrimetry method appears to be an appropriate choice between the two methods. l3 tables.

1982-12-01

333

Asilomar conference on managing complexity in high energy physics: A summary and renaming of the conference

The authors report the personal techniques and the results of CT-guided percutaneous drainage of postoperative abdominal fluid collections. CT-guided percutaneous drainage offers many advantages over surgery: it is less invasive, can be repeated and requires no anesthesia, there are not surgery-related risks and lower morbidity and mortality rates. Moreover, subsequent hospitalization is shorter and costs are consequently reduced. The authors conclude that CT-guided percutaneous drainage is the method of choice in the treatment of postoperative abdominal fluid collections.

1999-03-01

334

Applications of Bonner sphere detectors in neutron field dosimetry

The complex aspects of high energy physics work are briefly described, and approaches to managing them are discussed. Management of software and data are covered. For managing complexity in experimental physics, the choice of building or buying processor systems is addressed and the issues of compatibility and standardization are discussed. (LEW)

1987-02-01

335

A numerical weather prediction model--Computational aspects on the CRAY-1

The theory of neutron moderation and spectroscopy are briefly reviewed, and moderators that are useful for Bonner sphere spectrometers are discussed. The choice of the neutron detector for a Bonner sphere spectrometer is examined. Spectral deconvolution methods are briefly reviewed, including derivative, parametric, quadrature, and Monte Carlo methods. Calibration is then discussed. (LEW)

1983-09-01

336

A new solution of the Wheeler-De Witt equation

This paper presents a case study in the design and implementation of a numerical weather prediction model on a supercomputer (CRAY-1). Following a historical introduction to the evolution of the model, the governing equations of the model are presented and the numerical solution of these forecast equations is described. A brief tutorial on the architecture of the CRAY-1 is presented with a discussion of how it affects the choice of algorithms and code design of the model. A summary of the advantages gained by use of the vector aspects of the CRAY-1 is included.

1984-01-01

337

A new solution of the Wheeler-De Witt equation

We consider the problem of rotation in a homogeneous Bianchi type IX cosmological model. Studying the Wheeler-De Witt equation corresponding to this minisuperspace, and adopting a particular choice of the factor ordering, we are able to find a particular solution which is strongly peaked about isotropy. This result confirms all the previous investigations in this field, and suggests the conclusion that the machian nature of our universe is the natural, i.e. most likely, outcome of the Planck epoch. (orig.).

1991-06-06

338

ITER Blanket First Wall (WBS 1.6{sub 1}A)

We consider the problem of rotation in a homogeneous Bianchi type IX cosmological model. Studying the Wheeler-De Witt equation corresponding to this minisuperspace, and adopting a particular choice of the factor ordering, we are able to find a particular solution which is strongly peaked about isotropy. This result confirms all the previous investigations in this field, and suggests the conclusion that the machian nature of our universe is the natural, i.e. most likely, outcome of the Planck epoch. (orig.).

339

c-Jun N-terminal Kinase 2 Regulates Multiple Receptor Tyrosine Kinase Pathways in Mouse Mammary Tumor Growth and Metastasis

International Thermonuclear Experimental Reactor (ITER) project is the international collaboration one for the commercialization of nuclear fusion energy through the technical and engineering verification. In ITER project, we plan to procure the blanket systems which has the risk of technology and cost when it is newly developed. We are developing the manufacturing process and joining technology for the ITER blanket to complete the procurement with qualified blanket system. To evaluate the soundness of manufacturing process, specimen and mock-up tests are being prepared. Finally, we can obtain the key technology of nuclear fusion reactor especially on the blanket design, joining and manufacturing technology through the present project and these technologies will help the construction of Korea fusion DEMO reactor and the development of commercial nuclear fusion reactor in Korea. In 1st year, through the fabrication of the Cu/SS and Be/Cu joint ...

2008-03-15

340

Variations in Kinetic Properties of Ribulose-1,5-bisphosphate Carboxylases among Plants

c-Jun N-terminal kinase 2 (JNK2) isoforms are transcribed from the jnk2 gene and are highly homologous with jnk1 and jnk3 transcriptional products....Full Text Available

2011-01-01

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341

Urban Atmospheric Science

Studies of ribulose-1,5-bisphosphate (RuBP) carboxylase from taxonomically diverse plants show that the enzyme from C₃ and crassulacean acid metabolism pathway species exhibits lower K_m(CO₂)...Full Text Available

1981-06-01

342

Environmental Research Database

DescriptionThis new research programme activity on Urban Atmospheric Science will deliver aspects of the NERC strategy: Next Generation Science for Planet Earth. It has been developed as part of the Environment, Pollution & Human Health theme. Research in the Environment, Pollution & Human Health theme is directed at elucidating key environmental processes that form part of a causal pathway between an environmental hazard and disease outcome, and providing a predictive capability of the risk to human heal [continued...

2012-01-01

343

Up-Regulation of the RhoA/Rho-Kinase Signaling Pathway in Corpus Cavernosum from Endothelial Nitric-Oxide Synthase (NOS), but Not Neuronal NOS, Null Mice

Transcriptome sequencing and annotation of the microalgae Dunaliella tertiolecta: Pathway description and gene discovery for production of next-generation biofuels

We tested the hypothesis that the basal release of nitric oxide (NO) from endothelial cells modulates contractile activity in the corpus cavernosum (CC) via inhibition of the RhoA/Rho-kinase signaling...Full Text Available

2010-04-01

344

The mitogenic activity of human T-cell leukemia virus type I is T-cell associated and requires the CD2/LFA-3 activation pathway.

BackgroundBiodiesel or ethanol derived from lipids or starch produced by microalgae may overcome many of the sustainability challenges previously ascribed to petroleum-based fuels and first generation plant-based biofuels. The paucity of microalgae genome sequences, however, limits gene-based biofuel feedstock optimization studies. Here we describe the sequencing and de novo transcriptome assembly for the non-model microalgae species, Dunaliella tertiolecta, and identify pathways and genes of importance related to biofuel production.ResultsNext generation DNA pyrosequencing technology applied to D. tertiolecta transcripts produced 1,363,336 high quality reads with an average length of 400 bases. Following quality and size trimming, ~ 45% of the high quality reads were assembled into 33,307 isotigs with a 31-fold coverage and 376,482 singletons. Assembled sequences and singletons were subjected to BLAST similarity searches and annotated with Gene Ontology (GO) and ...

2011-03-14

345

The Putative Natural Killer Decoy Early Gene m04 (gp34) of Murine Cytomegalovirus Encodes an Antigenic Peptide Recognized by Protective Antiviral CD8 T Cells

The presence of a high number of activated T cells in the bloodstream and spontaneous proliferation of peripheral blood mononuclear cells in vitro are striking characteristics of human T-cell leukemia...Full Text Available

1993-06-01

346

Strategic pathways for energy in Brazil; Os caminhos da eficiencia energetica no Brasil

Several early genes of murine cytomegalovirus (MCMV) encode proteins that mediate immune evasion by interference with the major histocompatibility complex class I (MHC-I) pathway of antigen presentation...Full Text Available

2000-02-01

347

Stable Isotope Labeling, in Vivo, of d- and l-Tryptophan Pools in Lemna gibba and the Low Incorporation of Label into Indole-3-Acetic Acid ¹

The aim of this work is to suggest steps and policies to increase the introduction of cost-effective energy in conservation measures in Brazil. This report first addresses the motivations for a policy of energy efficiency and summarizes experiences in Brazil. It then considers the roles and perspectives of the diverse agents and review the instruments of policy. It concludes with an overview of strategic needs and lines of action.

1995-01-01

348

Silver nanoparticles inhibit VEGF-and IL-1?-induced vascular permeability via Src dependent pathway in porcine retinal endothelial cells

We present evidence that the role of tryptophan and other potential intermediates in the pathways that could lead to indole derivatives needs to be reexamined. Two lines of Lemna gibba...Full Text Available

1991-04-01

349

Selective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae

The aim of this study is to determine the effects of silver nanoparticles (Ag-NP) on vascular endothelial growth factor (VEGF)-and interleukin-1 beta (IL-1β)-induced vascular permeability, and...Full Text Available

350

Prostaglandin E₂ Signals Through PTGER2 to Regulate Sclerostin Expression

BackgroundWhen eukaryotic cells are deprived of amino acids, uncharged tRNAs accumulate and activate the conserved GCN2 protein kinase. Activated Gcn2p up-regulates the general amino...Full Text Available

351

Environmental Research Database

The Wnt signaling pathway is a robust regulator of skeletal homeostasis. Gain-of-function mutations promote high bone mass, whereas loss of Lrp5 or Lrp6 co-receptors decrease bone mass. Similarly, mutations...Full Text Available

352

Plant Sulphur Nutrition

DescriptionThe recent sequencing of the complete genomes of several streptomycete species revealed the presence of a large number of cryptic' secondary metabolic gene clusters, and led to the realisation that these organisms have the ability to produce many more natural products than had previously been recognised. One of the aims of our work is to identify the physiological signals and regulatory mechanisms responsible for the activation of these 'cryptic' pathways, thus unleashing the full biosynthetic p [continued...

2010-01-31

353

Pathways to equity in mathematics education: how life experiences impact researcher positionality

British Library Electronic Table of Contents (United Kingdom)

This study examined the life histories of a group of emerging scholars in the field of mathematics education who identify themselves as having a particular interest in and concern for issues of equity and diversity. Experiences of being the "other," "bearing witness" to "othering experiences," and "orienting experiences" in relation to issues of equity proved to be prominent themes in participants' life histories. These experiences were then linked to the positionality that these scholars now have in relation to their research in mathematics education.

2011-01-01

354

Pathogenesis of Ovarian Clear Cell Adenofibroma, Atypical Proliferative (Borderline) Tumor, and Carcinoma: Clinicopathologic Features of Tumors with Endometriosis or Adenofibromatous Components Support Two Related Pathways of Tumor Development

PI3K/Akt and mTOR/p70S6K Pathways Mediate Neuroprotectin D1-Induced Retinal Pigment Epithelial Cell Survival during Oxidative Stress-Induced Apoptosis

The clinicopathologic features of 472 ovarian epithelial clear cell neoplasms (4 adenofibromas [AFs], 41 atypical proliferative [borderline] tumors [APTs], and 427 carcinomas [CAs]) were studied in...Full Text Available

355

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

The initiation and progression of several forms of retinal degenerations involve excessive, repetitive, and/or sustained oxidative stress that, in turn, mediate photoreceptor cell damage and...Full Text Available

2010-06-01

356

Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.

Hyperthermia (HT) is a strong adjuvant treatment with radiotherapy and chemotherapy because it causes tumor reoxygenation. However, the detailed molecular mechanisms of how HT enhances tumor oxygenation...Full Text Available

2010-11-23

357

Involvement of stress-activated protein kinase and p38 mitogen-activated protein kinase in mIgM-induced apoptosis of human B lymphocytes

The yeast phosphatidylinositol transfer protein (Sec14p) is required for biogenesis of Golgi-derived transport vesicles and cell viability, and this essential Sec14p requirement is abrogated by inactivation...Full Text Available

1996-12-02

358

Insect-Induced Conifer Defense. White Pine Weevil and Methyl Jasmonate Induce Traumatic Resinosis, de Novo Formed Volatile Emissions, and Accumulation of Terpenoid Synthase and Putative Octadecanoid Pathway Transcripts in Sitka Spruce1[w

Despite intensive efforts, the intracellular signaling pathways that mediate apoptosis remain unclear. The human B lymphoma cell line, B104, possesses characteristics that make it an attractive model...Full Text Available

1996-11-26

359

Ingestion Pathway Consequences of a Major Release from SRTC

Stem-boring insects and methyl jasmonate (MeJA) are thought to induce similar complex chemical and anatomical defenses in conifers. To compare insect- and MeJA-induced terpenoid responses, we analyzed...Full Text Available

2005-01-01

360

Identification of Epidermal Pdx1 Expression Discloses Different Roles of Notch1 and Notch2 in Murine Kras^G12D-Induced Skin Carcinogenesis In Vivo

The food ingestion consequences due to radioactive particulates of an accidental release, scenario 1-RD-3, are evaluated for Savannah River Technology Center. The sizes of land areas requiring the protective action of food interdiction are calculated. The consequences of the particulate portion of the release are evaluated with the HOTSPOT model and an EXCEL spreadsheet for particulates.

1999-06-08

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

361

Homocysteine effects classical pathway of GPCR down regulation: G?_q/11, G?_12/13, G_i/o

BackgroundThe Ras and Notch signaling pathways are frequently activated during development to control many diverse cellular processes and are often dysregulated during tumorigenesis....Full Text Available

362

Highly Pathogenic H5N1 Avian Influenza: Entry Pathways into North America via Bird Migration

G protein-coupled receptors (GPCRs) are known to modulate intracellular effectors involved in cardiac function. We recently reported homocysteine (Hcy)-induced ERK-phosphorylation was suppressed...Full Text Available

2009-01-01

363

Growth differentiation factor-9 stimulates progesterone synthesis in granulosa cells via a prostaglandin E₂/EP2 receptor pathway

Given the possibility of highly pathogenic H5N1 avian influenza arriving in North America and monitoring programs that have been established to detect and track it, we review intercontinental movements...Full Text Available

364

Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection.

Growth differentiation factor-9 (GDF-9), an oocyte-secreted member of the transforming growth factor β superfamily, progesterone receptor, cyclooxygenase 2 (Cox2; Ptgs2), and the EP2 prostaglandin...Full Text Available

2000-08-29

365

Forkhead Box Transcription Factor FOXO3a Regulates Estrogen Receptor Alpha Expression and Is Repressed by the Her-2/neu/Phosphatidylinositol 3-Kinase/Akt Signaling Pathway

African bovine trypanosomiasis caused by Trypanosoma sp., is a major constraint on cattle productivity in sub-Saharan Africa. Some African Bos taurus breeds are highly tolerant of infection, but the potentially more productive Bos indicus zebu breeds are much more susceptible. Zebu cattle are well adapted for plowing and haulage, and increasing their tolerance of trypanosomiasis could have a major impact on crop cultivation as well as dairy and beef production. We used three strategies to obtain short lists of candidate genes within QTL that were previously shown to regulate response to infection. We analyzed the transcriptomes of trypanotolerant N'Dama and susceptible Boran cattle after infection with Trypanosoma congolense. We sequenced EST libraries from these two breeds to identify polymorphisms that might underlie previously identified quantitative trait loci (QTL), and we assessed QTL regions and candidate loci for evidence of selective sweeps. The scan of the EST sequences ...

2011-05-18

366

Folate fortification of rice by metabolic engineering

The expression status of the estrogen receptor alpha (ERα) and that of the epidermal growth factor receptor Her-2/neu frequently correlate inversely in breast cancers. While ERα-dependent...Full Text Available

2004-10-01

367

British Library Electronic Table of Contents (United Kingdom)

Rice, the world's major staple crop, is a poor source of essential micronutrients, including folates (vitamin B9). We report folate biofortification of rice seeds achieved by overexpressing two Arabidopsis thaliana genes of the pterin and para-aminobenzoate branches of the folate biosynthetic pathway from a single locus. We obtained a maximal enhancement as high as 100 times above wild type, with 100 g of polished raw grains containing up to four times the adult daily folate requirement.

2007-01-01

368

Essential Role for Cellular Phosphoglucomutase in Virulence of Type 3 Streptococcus pneumoniae

Elucidating novel pathways and regulation of nitrogen assimilation in alpha proteobacteria exemplified by the soil organism Paracoccus denitrificans

Synthesis of the Streptococcus pneumoniae type 3 capsule requires the pathway glucose-6-phosphate (Glc-6-P) → Glc-1-P → UDP-Glc → UDP-glucuronic acid (UDP-GlcUA)...Full Text Available

2001-04-01

369

Environmental Research Database

DescriptionThe importance of inorganic nitrate for the nutrition and growth of marine and freshwater autotrophic phytoplankton has long been recognised, in particularly because of the 'blooms' formed in nitrate and phosphate polluted water and their possible roles as carbon dioxide sinks. By contrast, the utilisation of nitrate by heterotrophic bacteria has historically received less attention. Up until now, the primary role of heterotrophic bacteria has classically been considered to be the decomposition [continued...

2010-01-31

370

Canonical and Alternative Pathways in Cyclin-Dependent Kinase 1/Cyclin B Inactivation upon M-Phase Exit in Xenopus laevis Cell-Free Extracts

BosR (BB0647) Controls the RpoN-RpoS Regulatory Pathway and Virulence Expression in Borrelia burgdorferi by a Novel DNA-Binding Mechanism

Cyclin-Dependent Kinase 1 (CDK1) is the major M-phase kinase known also as the M-phase Promoting Factor or MPF. Studies performed during the last decade have shown many details of how CDK1 is regulated...Full Text Available

371

Antigenic drift in influenza virus H3 hemagglutinin from 1968 to 1980: multiple evolutionary pathways and sequential amino acid changes at key antigenic sites.

In Borrelia burgdorferi (Bb), the Lyme disease spirochete, the alternative σ factor σ⁵⁴ (RpoN) directly activates transcription of another alternative σ...Full Text Available

2011-02-01

372

ATP-gated P2X₃ receptors constitute a positive autocrine signal for insulin release in the human pancreatic ? cell

Surveys of the antigenic properties of a wide range of variants of the H3N2 (Hong Kong) influenza virus subtype have revealed complex patterns of variants cocirculating during each of the main epidemic...Full Text Available

1983-10-01

373

ARSENIC TRIOXIDE INDUCES A BECLIN-1 INDEPENDENT AUTOPHAGIC PATHWAY VIA MODULATION OF SNON/SKIL EXPRESSION IN OVARIAN CARCINOMA CELLS

Extracellular ATP has been proposed as a paracrine signal in rodent islets, but it is unclear what role ATP plays in human islets. We now show the presence of an ATP signaling pathway that enhances...Full Text Available

2010-04-06

374

A Combinatorial Interplay Among the 1-Aminocyclopropane-1-Carboxylate Isoforms Regulates Ethylene Biosynthesis in Arabidopsis thaliana

Arsenic trioxide (As₂O₃), used to treat promyelocytic leukemia, triggers cell death via unknown mechanisms. To further our understanding of As₂O₃-induced...Full Text Available

2010-12-01

375

Upper reactor core supporting structure of highly earthquake-proof type

Ethylene (C₂H₄) is a unique plant-signaling molecule that regulates numerous developmental processes. The key enzyme in the two-step biosynthetic pathway of ethylene is 1-aminocyclopropane-1-carboxylate...Full Text Available

2009-11-01

376

US Army workshop on low-heat-rejection engines (4th). Sessions report for 29-31 March 1989

Fuel assemblies in a reactor pressure vessel are disposed in a reactor core shroud. The own weight of the fuel assembly is supported by a reactor core support plate, and is supported, for the horizontal direction, by an upper lattice plate and the reactor core support plate. A support portion for the upper portion of the fuel assembly is disposed above the fuel assembly, and a support portion for the support portion described above is joined to a shroud head by welding. The support portion for the upper portion of the fuel assembly has a network-like portion which absorbs and disperses rising force which exerted on the fuel assembly when the fuel assembly is risen by seismic forces. The rising force exerted on the fuel assembly absorbed by the network-like portion is effectively transferred to the shroud head by the support portion. With such a constitution, rising of the fuel assembly can be prevented against the seismic vibrations having prominent vertical ...

1993-05-14

377

The advanced CANDU reactor: The next step in safety and economics

There are a number of characteristics exhibited by ceramic materials that may provide potential benefits for the reciprocating internal combustion engine. However, the brittle nature of these materials together with a variability in strength has created difficulties in applying ceramic materials to the engine environment. Although a wide range of physical properties is available from contemporary ceramic materials, a material offering consistently high strength has yet to be developed. For sliding-contact applications, desirable characteristics include good wear resistance, low friction, ability to join metals and good heat dissipation. Test results have shown that cam/follower components with cast iron cam sliding on a silicon nitride follower exhibit very low wear rates. The application of silicon carbide to face seals has also shown substantial reductions in both friction and wear when compared with conventional materials. The use of ceramic materials for ...

1989-03-31

378

The ITER divertor cassette project

The Advanced CANDU Reactor (ACR"T"M) is the 'Next Generation' CANDU"R reactor, aimed at safe, reliable power production at a capital cost significantly less than that of current reactors such as the very successful CANDU 6 reactors (e.g., Wolsong 1-4). The Wolsong 1-4 units are being joined by the Qinshan Phase 3 units in China as the current successful examples of CANDU technology. The ACR design builds on this knowledge base, adding a selected group of innovations to obtain substantial cost reduction while retaining a proven design basis. The ACR maximizes the use of components and equipment applications that are well proven through CANDU and other nuclear experience. Joint development of equipment designs and specifications with manufactures has been emphasized. Similarly, the ACR design emphasizes constructability, and takes advantage of inherent CANDU features to enable short project and construction schedules. Overall, the ACR design represents a balance of ...

2003-04-01

379

Testing of Critical Features of Polysilicon MEMS

The divertor 'Large Project' was conceived with the aim of demonstrating the feasibility of meeting the lifetime requirements by employing the candidate armor materials of beryllium, tungsten (W) and carbon-fiber-composite (CFC). At the start, there existed only limited experience with constructing water-cooled high heat flux armored components for tokamaks. To this was added the complication posed by the need to use a silver-free joining technique that avoids the transmutation of n-irradiated silver to cadmium. The research project involving the four Home Teams (HTs) has focused on the design, development, manufacture and testing of full-scale Plasma Facing Components (PFCs) suitable for ITER. The task addressed all the issues facing ITER divertor design, such as providing adequate armor erosion lifetime, meeting the required armor-heat sink joint lifetime and heat sink fatigue life, sustaining thermal-hydraulic and electromechanical loads, and seeking to identify ...

1999-12-01

380

Sympatric Distribution of Three Human Taenia Tapeworms Collected between 1935 and 2005 in Korea

The behavior of MEMS devices is limited by the strength of critical features such as thin ligaments, oxide cuts joining layers, pin joints and hinges. Devices fabricated at Sandia's Microelectronic Development Laboratory have been successfully tested to investigate these features. A series of measurements were performed on samples with gage lengths of 15 to 1000 microns, using conventional and tungsten coated samples as well as samples that include the critical features of standard components in the test section. Specimens have a freely moving pin joint on one end that anchors the sample to the silicon die to allow rotation to reduce effects of bending. Each sample is loaded in uniaxial tension by pulling laterally with a flat tipped diamond in a computer-controlled Nanoindenter. Load is calculated by resolving the measured lateral and normal forces into the applied tensile force and frictional losses. The specimen cross section and gage length dimensions ...

1999-12-02

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381

String Junctions and Holographic Interfaces

Taeniasis has been known as one of the prevalent parasitic infections in Korea. Until recently, Taenia saginata had long been considered a dominant, and widely distributed species but epidemiological profiles of human Taenia species in Korea still remain unclear. In order to better understand distribution patterns of human Taenia tapeworms in Korea, partial nucleotide sequences of mitochondrial cox1 and ITS2 (internal transcribed spacer 2) were determined, along with morphological examinations, on 68 Taenia specimens obtained from university museum collections deposited since 1935. Genomic DNA was extracted from formalin-preserved specimens. Phylogenetic relationships among the genotypes (cox1 haplotype) detected in this study were inferred using the neighbor-joining method as a tree building method. Morphological and genetic analyses identified 3 specimens as T. solium, 51 specimens as T. asiatica, and 14 specimens as T. saginata. Our results indicate that all 3 ...

2008-12-20

382

Soil less culture; I sistemi di coltivazione senza suolo

In this paper we study half-BPS type IIB supergravity solutions with multiple $AdS_3\\times S^3\\times M_4$ asymptotic regions, where $M_4$ is either $T^4$ or $K_3$. These solutions were first constructed in [1] and have geometries given by the warped product of $AdS_2 \\times S^2 \\times M_4 $ over $\\Sigma$, where $\\Sigma$ is a Riemann surface. We show that the holographic boundary has the structure of a star graph, i.e. $n$ half-lines joined at a point. The attractor mechanism and the relation of the solutions to junctions of self-dual strings in six-dimensional supergravity are discussed. The solutions of [1] are constructed introducing two meromorphic and two harmonic functions defined on $\\Sigma$. We focus our analysis on solutions corresponding to junctions of three different conformal field theories and show that the conditions for having a solution charged only under Ramond-Ramond three-form fields reduce to relations involving the positions of the poles ...

2010-01-01

383

Renewable energy in the urban setting: Year two

The paper gives a general view of techniques and systems related to soil less culture developed in the last years (on substrate in beg; NFT; Ebb-Flood, aeroponic,..) taking into account their management and problems (water quality, control of plant nutrition and irrigation; substrates; pathological aspects,..). The evolution, now in progress, of soil less culture from open to closed system as a way to realized an environmental friendly growing system, is considered. When plants are grown with open cycle techniques a large amount of waste solution, with an a high content of nutrients, are discharged in soil and water. Furthermore, they need an extra-utilization of water and fertilizers. Another aspect is the utilization of low cost substrates, which can be reused for more than one cultural cycle without negative effects on yield, and also finally discharged without negative effects on the environment. The development of soil less culture in countries, such as Italy, where only in the ...

1996-01-01

384

Reactor fuel cladding tube with excellent corrosion resistance and method of manufacturing the same

At the 1996 Conference in North Carolina, The Green Institute began to share its story. Their presentation this year will cover where they are in the design process and their plans for using solar and wind technologies in the development of an Eco-Industrial Park and Business Incubator. Located in a Federal Enterprise Community in Minneapolis, this project borrows sustainable and green building principles using the Rocky Mountain Institute and Solar Living Center as models. Using a change in the paradigm regarding how industry does business, The Green Institute is joining with developments across the country that are putting together Eco-Industrial Parks which use closed loop production systems to reduce waste and emissions generated from manufacturing processes. Using renewable energy, both solar and wind, presents challenges both in the integration of systems on this small site and the educational opportunities with a large potential audience outside the ...

1997-12-31

385

Portable fluid X-ray diagnostic system

The present invention provides a fuel cladding tube having an excellent corrosion resistance and thus a long life, and a suitable manufacturing method therefor. Namely, in the fuel cladding tube, the outer circumference of an inner layer made of a zirconium base alloy is coated with an outer layer made of a metal more corrosion resistant than the zirconium base alloy. Ti or a titanium alloy is suitable for the corrosion resistant metal. In addition, the outer layer can be coated by a method such as vapor deposition or plating, not limited to joining of the inner layer material and the outer layer material. Specifically, a composite material having an inner layer made of a zirconium alloy coated by the outer material made of a titanium alloy is applied with hot fabrication at a temperature within a range of from 500 to 850degC and at a fabrication rate of not less than 5%. The fabrication method includes any of extrusion, rolling, drawing, and casting. As the ...

1993-07-14

386

Monovalent cation-induced structure of telomeric DNA: The G-quartet model

A portable X-ray image system is described comprising: (a) a base assembly including panels and hinges joining the panels together along edges, and compression stops for biasing the hinges to compensate for the weight of payload when mounted on the base assembly, the compression stops being located for interaction with the hinges for biasing the panels to exhibit upward bowing when laid upon a flat surface prior to loading, and to provide resiliency for facilitating the base assembly assuming a substantially flat configuration when a predetermined payload is placed upon the base assembly; (b) an X-ray member; (c) apparatus for detachably mounting a table member to the base assembly to hold the table member at a location above the base; (d) an X-ray source; (e) means for sensing X-rays to form an image; (f) means for mounting the X-ray source and the X-ray sensing means on opposite sides relative to the table member and supported by the base assembly; (g) releasable ...

1989-02-14

387

Manufacturing of small scale W monoblock mockups by hot radial pressing

We have investigated the structures formed by oligonucleotides composed of two or four repeats of the telomeric sequences from Oxytricha and Tetrahymena. The Oxytricha four-repeat molecule (d(T4G4)4 = Oxy-4) forms structures with increased electrophoretic mobility in nondenaturing gels containing Na+, K+, or Cs+, but not in gels containing Li+ or no added salt. Formation of the folded structure results in protection of a set of dG's from methylation by dimethyl sulfate. Efficient UV-induced cross-links are observed in Oxy-4 and the related sequence from Tetrahymena (d(T2G4)4 = Tet-4), and join thymidine residues in different repeats. Models proposed to account for these data involve G-quartets, hydrogen-bonded structures formed from four guanosine residues in a square-planar array. We propose that the G-quartet structure must be dealt with in vivo by the telomere replication machinery.

1989-12-01

388

Manufacturing and testing of monoblock tungsten small-scale mock-ups

In the frame of the European Technology R and D programme for International thermonuclear experimental reactor (ITER) and in the area of high heat flux plasma facing components (HHFC), representative small-scale mock-ups were manufactured and tested to compare different concepts and joining technologies (i.e. active brazing, hot isostatic pressing (HIPping), diffusion bonding, etc.). On the basis of the results obtained by thermal fatigue tests, the monoblock concept resulted to be the most robust one, particularly when the HIPping manufacturing technology is used. Within this programme, ENEA developed an alternative technique for manufacturing plasma-facing components with a monoblock geometry of the ITER machine. The basic idea of this technique, named hot radial pressing (HRP), is to perform a radial diffusion bonding between the cooling tube and the armour tile by pressurising the internal tube only and by keeping the process parameters within the range in ...

2003-09-01

389

Manufacturing and testing of monoblock tungsten small-scale mock-ups

In the frame of the European Technology R and D program for ITER, and in the area of High Heat Flux plasma facing Components (HHFC), representative small-scale mock-ups were manufactured and tested to compare different concepts and joining technologies (i.e. active brazing, Hot Isostatic Pressing (HIPping), diffusion bonding, etc.). On the basis of the results obtained by thermal fatigue tests, the monoblock concept resulted to be the most promising one, particularly when the HIPping manufacturing technology is used. Within this program, ENEA manufactured tungsten monoblock mock-ups by using the HIPping technology. The mock-ups were tested with respect to thermal fatigue and, upon screening tests, the best performance obtained was 15 MW/m{sup 2} for 200 cycles. One of these mock-ups was enclosed in the 'Paride' neutron irradiation campaign. This campaign has the scope of enlarging the available database on the performance degradation of ...

2001-10-01

390

Joining of boron carbide using nickel interlayer

In the frame of the European Technology R and D program for ITER, and in the area of High Heat Flux plasma facing Components (HHFC), representative small-scale mock-ups were manufactured and tested to compare different concepts and joining technologies (i.e. active brazing, Hot Isostatic Pressing (HIPping), diffusion bonding, etc.). On the basis of the results obtained by thermal fatigue tests, the monoblock concept resulted to be the most promising one, particularly when the HIPping manufacturing technology is used. Within this program, ENEA manufactured tungsten monoblock mock-ups by using the HIPping technology. The mock-ups were tested with respect to thermal fatigue and, upon screening tests, the best performance obtained was 15 MW/m"2 for 200 cycles. One of these mock-ups was enclosed in the 'Paride' neutron irradiation campaign. This campaign has the scope of enlarging the available database on the performance degradation of prototypical basic solutions of ...

2001-10-01

391

Hydrogen utilization efficiency in PEM fuel cells

Carbide ceramics such as boron carbide due to their unique properties such as low density, high refractoriness, and high strength to weight ratio have many applications in different industries. This study focuses on direct bonding of boron carbide for high temperature applications using nickel interlayer. The process variables such as bonding time, temperature, and pressure have been investigated. The microstructure of the joint area was studied using electron scanning microscope technique. At all the bonding temperatures ranging from 1150 to 1300degC a reaction layer formed across the ceramic/metal interface. The thickness of the reaction layer increased by increasing temperature. The strength of the bonded samples was measured using shear testing method. The highest strength value obtained was about 100 MPa and belonged to the samples bonded at 1250 for 75 min bonding time. The strength of the joints decreased by increasing the bonding temperature above 1250degC. The results of this ...

392

Homology analyses of the protein sequences of fatty acid synthases from chicken liver, rat mammary gland, and yeast

In this paper, we present the work carried out within the framework of the FEVER project (Fuel cell Electric Vehicle for Efficiency and Range), an European project coordinated by Renault, joining Ecole des Mines de Paris, Ansaldo, De Nora, Air Liquide and Volvo. For the FEVER project, where an electrical air compressor is used for oxidant supply, there is no need for hydrogen spill over, meaning that the hydrogen stoichiometry has to be as close to one as possible. To determine the optimum hydrogen utilization efficiency for a 10 kW Proton Exchange Membrane Fuel Cell (PEMFC) fed with pure hydrogen, a 4 kW prototype fuel cell was tested with and without a hydrogen recirculator at the test facility of Ecole des Mines de Paris. Nitrogen cross over from the cathodic compartment to the anodic compartment limits the hydrogen utilization of the fuel cell without recirculator to 97.4 % whereas 100% is feasible when a recirculator is used. 5 refs.

1998-07-01

393

High performance ultra-steels with recyclable design

Homology analyses of the protein sequences of chicken liver and rat mammary gland fatty acid synthases were carried out. The amino acid sequences of the chicken and rat enzymes are 67% identical. If conservative substitutions are allowed, 78% of the amino acids are matched. A region of low homologies exists between the functional domains, in particular around amino acid residues 1059-1264 of the chicken enzyme. Homologies between the active sites of chicken and rat and of chicken and yeast enzymes have been analyzed by an alignment method. A high degree of homology exists between the active sites of the chicken and rat enzymes. However, the chicken and yeast enzymes show a lower degree of homology. The DADPH-binding dinucleotide folds of the {beta}-ketoacyl reductase and the enoyl reductase sites were identified by comparison with a known consensus sequence for the DADP- and FAD-binding dinucleotide folds. The active sites of all of the enzymes are primarily in hydrophobic regions of ...

1989-11-01

394

Evolution of the triangle zone in the Rocky Mountains Foothills near Coalspur, Central Alberta

The global production of steel is predicted to increase rapidly to meet future demands. In order to conserve the natural resources, certain measures must be taken. These include perfecting the recycling of steel, improving the performance to extend the life of the material, and reduce the need for massive production of steel by increasing the strength of the material. This paper presented a design concept for ultrafine complex microstructure steel. The National Research Institute for Metals in Japan has worked on a project which investigated 800 MPa ferrite steel for welded structures with a chemical composition similar to 400 MPa-class plain carbon steel. The doubled strength was attributed to grain refinement. Novel welding techniques were also used for joining the ultrafine microstructure. In this study, low carbon Si-Mn ferrite-pearlite steels were subjected to a thermo-mechanical treatment to produce a microstructure of 1 micron order ultrafine grain ferrite ...

2000-07-01

395

Energy report Frankfurt am Main 1992; Stadt Frankfurt am Main. Energiebericht 1992

A triangle zone, which commonly occurs along the external margin of a foreland thrust and fold belt with a buried thrust front, is underlain by a subhorizontal, blind, foreland-verging thrust that ends against a foreland-dipping, hinterland-verging thrust. These contemporaneous thrusts, active towards the end of orogenesis, enclose an intercutaneous wedge that moved towards the foreland. During orogenesis, a triangle zone evolves through periodic replacement of faults bounding the active wedge. Replacements occur in cycles during each of which a lower fault tends to be replaced by one in a lower stratigraphic horizon, an upper fault by one farther away from the foreland. Each cycle ends with the lower fault moving to a younger horizon where it joins a new, more external upper fault. Near Coalspur, the triangle zone exposes the remnants of several wedges involving Upper Cretaceous and Palaeocene molasse. Most of these wedges developed during the last cycle but one ...

1987-08-01

396

Current status and future plan of JMTR Hot Laboratory

By joining the `climate association of European cities`, Frankfurt has agreed to reduce its CO{sub 2}-emissions by 50% by the year 2010. The so-called `climate offense 1991` was the first regulatory paper to be set up by a community to reach this goal over a long term. This report now represents the present level of the project. Main points are the development of houses with low entropy, the retrofitting of heating systems, water saving measures and energy management. (BWI) [Deutsch] Durch den Beitritt zum `Klima-Buendnis der Europaeischen Staedte` hat sich die Stadt Frankfurt/M. verpflichtet, die CO{sub 2}-Emissionen bis zum Jahr 2010 um 50% zu senken. Mit der sog. `Klimaoffensive 1991` wurde dann erstmals von einer Kommune in Deutschland ein detailliertes Regelwerk aufgestellt, um dieses Ziel langfristig erreichen zu koennen. Der vorliegende Bericht stellt den aktuellen Stand des Projektes dar. Kernpunkte sind die Entwicklung von Niedrigentropiehaeusern, die ...

1993-12-31

397

Constraining the Dark Energy Equation of State using Alternative High-z Cosmic Tracers

The newly developed techniques by the Hot Laboratory (JMTR HL) have provided for us the key information on behavior of specimens due to mechanical / physical / chemical / synergistic effects of radiation, stress and water for fission and fusion reactor environment. These techniques are focused on several topics as follows; (1) miniaturized specimen test for the development of fusion reactor materials, (2) slow strain rate tensile testing (SSRT) and crack propagation measuring tests for the study of Irradiation Assisted Stress Corrosion Cracking (IASCC) of core internals of LWR, (3) handling technique on specimens including tritium for the research and development of tritium breeders and neutron multiplier as fusion blanket materials, (4) joining method using the Tungsten Inert Gas (TIG) welding technique for re-assembling of capsule and re-fabrication of specimen and (5) nondestructive evaluation using ultrasonic wave and infrared thermography for the quantitative ...

1999-08-01

398

Are there SO_2 externality costs beyond the Clean Air Act Amendments of 1990?

We propose to use alternative cosmic tracers to measure the dark energy equation of state and the matter content of the Universe [w(z) & Omega_m]. Our proposed method consists of two components: (a) tracing the Hubble relation using HII galaxies which can be detected up to very large redshifts, z~4, as an alternative to supernovae type Ia, and (b) measuring the clustering pattern of X-ray selected AGN at a median redshift of z~1. Each component of the method can in itself provide interesting constraints on the cosmological parameters, especially under our anticipation that we will reduce the corresponding random and systematic errors significantly. However, by joining their likelihood functions we will be able to put stringent cosmological constraints and break the known degeneracies between the dark energy equation of state (whether it is constant or variable) and the matter content of the universe and provide a powerful and alternative route to measure the ...

2009-01-01

399

Alternative High-z Cosmic Tracers and the Dark Energy Equation of State

Inclusion of environmental externality costs in the selection of utility resources has become a reality in New York, Massachusetts, Nevada and California. Soon several other jurisdictions are likely to join these states in using environmental externality costs in decision-making. The consideration of environmental externalities are bound to profoundly affect utility decision-making in the future. So far attention has focused largely on air emission externalities of SO_2, NO_x and CO_2. However, the recent Clean Air Act Amendments (CAAA) will reduce SO_2 emissions from utilities by about 50 percent. With such a large reduction in SO_2 loading, the question has been raised as to the need to further consider SO_2 externality costs in decision-making. This paper comments on this issue. By using generation and emission data from New York utilities, the paper shows that SO_2 emission externalities exist even after complying with requirements of the CAAA.

1992-06-21

400

A New Landscape: Opportunities and Pitfalls for Universities Expanding in the Persian Gulf

We propose to use alternative cosmic tracers to measure the dark energy equation of state and the matter content of the Universe [w(z) & \\Omega_m]. Our proposed method consists of two components: (a) tracing the Hubble relation using HII-like starburst galaxies, as an alternative to SNIa, which can be detected up to very large redshifts, z~4, and (b) measuring the clustering pattern of X-ray selected AGN at a median redshift of ~1. Each component of the method can in itself provide interesting constraints on the cosmological parameters, especially under our anticipation that we will reduce the corresponding random and systematic errors significantly. However, by joining their likelihood functions we will be able to put stringent cosmological constraints and break the known degeneracies between the dark energy equation of state (whether it is constant or variable) and the matter content of the universe and provide a powerful and alternative rute to measure the ...

2009-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

401

Innovative Structural and Joining Concepts for Lightweight Design of Heavy Vehicle Systems

Dozens of universities--primarily from the United States, United Kingdom, and Australia--are eyeing the Gulf region as a largely untapped reservoir of academic potential and economic opportunity. During the last few years, UAE states like Dubai, Abu Dhabi, Qatar, and Ras al Khaymah have spent billions to entice top universities. And many colleges are responding--examples include New York University's campus in Abu Dhabi; Michigan State University's school in Dubai; and big names like Cornell, Northwestern, and Carnegie Mellon that have set up shop in Qatar. Typically, Western universities begin their foray into the Gulf by teaming with local investors. The colleges oversee the academic infrastructure while the investors front all operational costs. The partnerships are complicated. Some investors are mining the UAE's educational zeal for profit. In other cases, schools join forces with the region's numerous royal families, who are mostly interested in furthering ...

2008-12-01

402

Clinically silent heterotaxy with polysplenia syndrome and IVC azygous continuation draining to SVC: CT findings. Case report

The extensive research and development effort was initiated by the U.S. Department of Energy (DOE) in 2002 at West Virginia University (WVU) in order to investigate practical ways of reducing the structural weight and increasing the durability of heavy vehicles through the judicious use of lightweight composite materials. While this project was initially focused on specific Metal Matrix Composite (MMC) material, namely Aluminum/Silicon Carbide (Al/SiC) commercially referenced as ''LANXIDE'', the current research effort was expanded from the component level to the system level and from MMC to other composite material systems. Broadening the scope of this research is warranted not only by the structural and economical deficiencies of the ''LANXIDE'' MMC material, but also by the strong coupling that exists between the material and the geometric characteristics of the structure. Such coupling requires a truly ...

2006-09-30

403

Vibration signature analysis of AFM images

Patients with heterotaxy syndrome often have complex cardiac and extracardiac anomalies requiring further detailed diagnostic evaluation. They often present severe cardiac failure early in life. Newer radiological modalities in the form of spiral computed tomography (CT) and three-dimensional reconstruction of spiral CT allow clear definition of the anatomy of these anomalies. A 59-year-old woman was diagnosed with polysplenia and multiple anomalies in an abdominal ultrasonography (US) during a control medical examination due to a trivial dietary mistake. She was then referred to our institution for further examination of these anomalies and an additional thoraco-abdominal computed tomography (CT) examination. The patient was totally asymptomatic at the time of admission. There was no significant past history and no abnormal laboratory data. We performed abdominal, pelvic and thoracic CT examinations using Somatom Siemens Emotion scanner. Non-enhanced sections were obtained with 8 mm ...

2007-01-01

404

The "Caring" Role in a Child Care Center. Staff Development Series, Military Child Care Project. Part II: Relating to Parents.

Vibration signature analysis has been commonly used for the machine condition monitoring and the control of errors. However, it has been rarely employed for the analysis of the precision instruments such as an atomic force microscope (AFM). In this work, an AFM was used to collect vibration data from a sample positioning stage under different suspension and support conditions. Certain structural characteristics of the sample positioning stage show up as a result of the vibration signature analysis of the surface height images measured using an AFM. It is important to understand these vibration characteristics in order to reduce vibrational uncertainty, improve the damping and structural design, and to eliminate the imaging imperfections. The choice of method applied for vibration analysis may affect the results. Two methods, the data dependent systems (DDS) analysis and the Welch`s periodogram averaging method were investigated for application to this problem. Both ...

1995-12-31

405

Report on the present day situation and technical perspectives of renewable energies; Rapport sur l'etat actuel et les perspectives techniques des energies renouvelables

Material related to routine as well as sensitive aspects of parent/day care center relationships is presented in this training module, one of a series providing staff development information for programs operated for dependents of military personnel. The module offers a brief discussion of ways caregivers can help parents feel at ease about leaving their children in child care and presents a set of multiple-choice skill-building exercises for effectively working with parents. Exercises focus on various topics, including how parents can be approached when their child may have a health problem, when child abuse or neglect is suspected, and when parental cooperation is needed to stop a child's undesirable or disruptive behavior. Exercises are also devoted to the questions of whether or not caregivers should act as advisors to parents or tell parents about their child's behavior at the center. Concluding exercises indicate how caregivers can handle parent requests for ...

1982-04-01

406

PDE-based Non-Linear Diffusion Techniques for Denoising Scientific and Industrial Images: An Empirical Study

This work, carried out by the parliamentary office for the evaluation of scientific and technological choices on request of the French National Assembly and Senate, takes stock of the present day situation and technical perspectives of development of renewable energy sources and of research needs of the French industry in this domain: 1 - renewable energies: key-technologies for the energy supply of developing countries and for a rational consumption in transportation systems and accommodations of developed countries (energies technically different from fossil or nuclear energies; fundamental energy sources for a developing world; different national goals in Europe depending on the available natural resources and on the political realities; a minor interest in France for the domestic power generation but a major interest for transports, residential and tertiary sectors and export); 2 - priority choices given to the French renewable energy ...

2001-11-01

407

Consumer choice and suggested price for pork as influenced by its appearance, taste and information concerning country of origin and organic pig production

Removing noise from data is often the first step in data analysis. Denoising techniques should not only reduce the noise, but do so without blurring or changing the location of the edges. Many approaches have been proposed to accomplish this; in this paper, they focus on one such approach, namely the use of non-linear diffusion operators. This approach has been studied extensively from a theoretical viewpoint ever since the 1987 work of Perona and Malik showed that non-linear filters outperformed the more traditional linear Canny edge detector. They complement this theoretical work by investigating the performance of several isotropic diffusion operators on test images from scientific domains. They explore the effects of various parameters such as the choice of diffusivity function, explicit and implicit methods for the discretization of the PDE, and approaches for the spatial discretization of the non-linear operator etc. They also compare these schemes with ...

2001-12-20

408

Adiabatic interpretation of particle creation in a de Sitter universe

Reactions of consumers to the appearance and taste of pork with and without information concerning outdoor production of pigs were tested in France, Denmark, Sweden and UK. Consumers in all four countries focussed on colour and fatness rather than marbling and drip to make their choice. Almost half of the British and Danish preferred the paler and the French the darker pork. Most people preferred the leaner pork. When information was provided in the form of labels, the vast majority of consumers preferred the pork labelled as originating from their own country as opposed to 'imported' and that labelled as pork from pigs 'raised outside' as opposed to 'inside'. There was no difference in the taste of grilled pork from indoor and outdoor production systems but pork labelled 'home produced' or 'outdoor' were more appreciated. Consumers' willingness to pay varied widely and was higher for those consumers who found more of the characteristics they sought. Consumers ...

2005-01-01

409

Versatile charged particle activation technique for the analysis of the noble metals

The choice of vacuum state for a quantum scalar field propagating in a de Sitter spacetime (massive and arbitrarily coupled to the gravitational field) is discussed. The problem of finite-time initial conditions for the mode functions is analyzed, as well as how these determine the vacuum state of the quantum system. The principle guiding the choice of vacuum state is the following: one wants the vacuum contribution to the energy-momentum tensor to contain all the ultraviolet divergent terms, so that the particle creation terms are finite, and covariantly conserved. There is a suitable set of modes (instantaneous adiabatic basis) in which this splitting of the expectation value of the energy-momentum tensor can be carried out. Numerical results are presented for different finite-time initial conditions (m = 0.6, {zeta} = 1/6). The nature of the particle creation effect is described and its relationship to the concept of a horizon crossing time ...

1998-06-10

410

Versatile charged particle activation technique for the analysis of the noble metals

The general usefulness of neutron activation analysis (NAA) for samples containing the platinum group elements (PGE) and Au, either as major or trace constituents, is discussed. Charged particle activation is shown to be a viable or complementary alternative. Proton (6-10 MeV) and alpha particle (9-15 MeV) beams, produced in a tandem Van de Graaff accelerator, have been established to be the most effective choice. By taking advantage of the Coulomb barrier effect and the fact that many charged particle induced reactions have relatively large threshold values, the same instrumental technique can be applied, with minor modifications, to a wide range of materials.

1982-01-01

411

The regional control of the canadian energy production; Le contraste provincial de la production energetique canadienne

The general usefulness of neutron activation analysis (NAA) for samples containing the platinum group elements and Au, either as major or trace constituents, is discussed. Charged particle activation is shown to be a viable or complementary alternative. Proton (6-10 MeV) and alpha particle (9-15 MeV) beams, produced in a Tandem van de Graaff accelerator, have been established to be the most effective choice. By taking advantage of the Coulomb barrier effect and the fact that many charged particle induced reactions have relatively large threshold values, the same instrumental technique can be applied, with minor modifications, to a wide range of materials.

1983-01-01

412

The monogamous reproductive strategy in Lepidoptera

This document provides information and presents data on the energy situation in many regions of Canada. The first part deals with the petroleum and the bitumen shales of Alberta (reserves, exploitation and production, environmental impacts), the second part discusses with the hydroelectricity choice of Quebec and the 2004 crisis. The nuclear situation of Ontario is presented in the third part (nuclear park, programs, uranium reserves, research and development on Candu reactors), while the fourth part deals with the renewable energies (wind power and biomass). The canadian situation facing the Kyoto protocol is discussed in the last part. (A.L.B.)

2004-12-01

413

British Library Electronic Table of Contents (United Kingdom)

On the basis of literary sources and experimental data, the advantages of a monogamous reproductive strategy are analyzed. Monogamous species of Lepidoptera have no postcopulative mechanisms of control over the success of reproductive sperm competition, cryptic female choice, and, probably, the male?s nuptial gift. Selection of the sex partner and of the quality of the future generation is determined by the precopulative and copulative mechanisms of the reproductive behavior, which include chemocommunication and a ?lock-and-key? mechanism. In an experiment with one male and one female, the quota of successful mating can depend on the morphological complication of the genital apparatus of males. Cases are considered of repeated mating for some, usually monogamous, species. In comparison wit...

2011-01-01

414

The Velocity of Money in a Life-Cycle Model

Second generation rotary furnaces, an even more viable alternative to cupola and electric induction furnaces; La seconde generation de fours rotatifs, un appareil qui peut se substituer avantageusement au cubilot et au four electrique a induction

The determinants of the velocity of money have been examined based on life-cycle hypothesis. The velocity of money can be expressed by reciprocal of the average value of holding time which is defined as interval between participating exchanges for one unit of money. This expression indicates that the velocity is governed by behavior patterns of economic agents and open a way to constructing micro-foundation of it. It is found that time pattern of income and expense for a representative individual can be obtained from a simple version of life-cycle model, and average holding time of money resulted from the individual's optimal choice depends on the expected length of relevant planning periods.

2005-01-01

415

Robust distributed model predictive control: A review and recent developments

Rotary furnaces are a well established alternative to cupola furnaces. Recent innovations in oxygas furnaces have made them the preferred choice even over medium-frequency electric furnaces in many European foundries. The article explains in what respects the rotary furnace is a new iron smelting concept, as different from the cupola furnace as the medium-frequency electric furnace. (author)

2001-10-01

416

British Library Electronic Table of Contents (United Kingdom)

Abstract This study presents a review of distributed model predictive control (DMPC) strategies followed by recent studies conducted by the authors on the robustness of these strategies to model errors and a summary of future challenges in this area. The review identifies three key challenges for the successful application of DMPC: (i) the selection of optimal control structure for DMPC; (ii) the choice of a suitable coordination strategy among the controllers; and (iii) the robustness of DMPC strategies to model errors. Then, the study summarises recent developments related to the robustness of unconstrained and constrained DMPC algorithms. For the unconstrained case, a methodology that is based on the calculation of a performance index is proposed to balance the trade-off between perform...

2011-01-01

417

Quantum tunnelling for Hawking radiation from a dynamical Black Hole

Proton beam monitoring and forming on the target of isotope complex at INR linac

The paper deals with Hawking radiation related to non-static spherically symmetric black hole. Quantum corrections are incorporated using Hamilton-Jacobi method beyond semi-classical approximation. It is found that different order correction terms satisfy identical differential equation as the semiclassical action and are solved by a typical technique. It has been shown that with proper choice of the proportionality factors, one loop back reaction effect in the space time can be obtained. Finally, using the law of black hole mechanics, a general modified form of the black hole entropy is obtained considering modified Hawking temperature.

2011-01-01

418

Post-transplant monitoring of renal allografts: are we there yet?

Special beam extraction channel is used at INR linac for isotope production. It starts from 160 MeV measuring and matching area of accelerator. This choice of beam extraction enables to direct to the target of isotope complex a proton beam of wide energy range up to 160 MeV. It is important for production of different types of nuclides. The measuring results of proton beam behavior in this region are presented. Required beam forming in 160 MeV measuring and matching area of accelerator and in beam extraction channel is discussed.

2010-01-01

419

British Library Electronic Table of Contents (United Kingdom)

Transplantation has emerged as the therapy of choice for many patients with end organ failure. One of the major goals is to tailor immunosuppressive therapy to the individual needs of every patient to balance the risk for rejection and over-immunosuppression. This will require diagnostic tools that can detect harmful processes in the allograft early, and that can be measured repeatedly. This review will consider recent advances in our understanding of the molecular nature of these processes and how this information is being utilized to design novel diagnostic assays to non-invasively monitor allografts. Highlighted is the need for large-scale prospective multi-centre studies to validate assays that show early promise in single centre studies.

2009-01-01

420

Particle emission in hydrodynamics: a problem needing a solution

Natural gas use in Saskatchewan hog industry

A survey of various mechanisms for particle emission in hydrodynamics is presented. First, in the case of sudden freeze out, the problem of negative contributions in the Cooper-Frye formula and ways out are presented. Then the separate chemical and thermal freeze out scenario is described and the necessity of its inclusion in a hydrodynamical code is discussed. Finally, we show how to formulate continuous particle emission in hydrodynamics and discuss extensively its consistency with data. We point out in various cases that the interpretation of data is quite influenced by the choice of the particle emission mechanism.

2004-01-01

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421

Medical Devices; Managing the Mismatch An Outcome of the Priority Medical Devices Project

A study was conducted to examine the energy consumption in existing and new hog farming facilities and to analyse the potential for increased natural gas use in the Saskatchewan hog industry. Existing heating/cooling, ventilation and feed mill equipment choices offer possibilities for running on electricity, natural gas or propane. Energy costs are lowest when natural gas is used. To put the study in context, an overview of the Saskatchewan hog industry was provided. The potential increase in natural gas use in hog production by year 2005 was estimated. 10 refs., 6 tabs., 8 figs.

1996-11-01

422

Measuring preferences for low-carbon energy technologies in South-East England: the case of electricity generation

Choosing a medical device is complex and requires a transparent process based on reason, evidence and assessment of prioritized public health needs. Poor choices lead to inappropriate use or non-use of medical devices and a waste of resources.This report suggests how an agenda to improve access to appropriate medical devices could be devised from applying the crucial 4 components - Availability, Accessibility, Appropriateness, and Affordability, to the 15 global high-burden diseases and some cross-cutting issues. The results of this exercise suggest several areas of research necessary to help

2010-01-01

423

Light construction vehicles: ample choice; Leichte Baufahrzeuge: Reiche Auswahl

This paper presents a survey on public preferences in SE England for the use of wind, biomass and nuclear power in electricity generation. Using a labelled CE the perceived importance (value) to the public of distance and the energy options' impacts on biodiversity, emissions, land occupation and household cost was explored. Results suggest that impacts, technology name, demographic characteristics, attitudes towards the environment, knowledge and experience with the technologies were significant choice determinants. Considering the current debate about the development of nuclear power and biomass in UK and worldwide, this survey provides an insight into the factors affecting public acceptability

2008-07-01

424

Implementation and management of Daya Bay Nuclear Power Plant in-core flux thimble tube in-service inspection

There are many types of allround trucks. But which is the adequate one for the manifold tasks in construction, horticulture and landscaping works? Passenger transport, load haulage and traction: the article takes a critical glance at what is on offer. (orig.) [German] Allroundlaster gibt es viele. Aber welcher ist der richtige fuer die vielfaeltigen Aufgaben am Bau und im Garten- und Landschaftsbau? Personen befoerdern, Lasten tragen und Anhaenger ziehen: Ein kritischer Blick aufs Angebot. (orig.)

1999-07-01

425

Immersions of Einstein-Riemann spacetimes in six-dimensional flat spaces

This article discusses the Daya Bay nuclear power plant in-core flux thimble tube in-service inspection method and strategy. High light of the multiple frequency eddy current technology adopted including frequency and probe choice, standard design, data acquisition process are involved. The wear defect-growing trends are studied on base of the history data, which contribute to the in-service inspection strategy decision. (authors)

2003-04-08

426

How Waste Management Can Be Influenced By Transport Packagings

Each choice of an arbitrary nonzero function f of the four immersion parameters is shown to determine 16N[f] distinguishable classes of two-parameter families of immersions of Einstein-Riemann spacetimes in six-dimensional flat spaces, where N[f] is the number of regular immersion parameter domains. The metric tensors, curvature tensors and the immersion loci are calculated in a closed form, and these calculations involve only finitely many algebraic operations. The presence of the arbitrary function provides the opportunity for study of the behaviour of multiple isolated singularities and/or 'shape' functions in general relativity.

2002-09-21

427

Gamma-gamma collider based on Compton back-scattering

With major D&D projects ongoing or being planned, and also with the daily management of radwaste from nuclear facilities, the potential role of transport packagings has often been overlooked: here will one rely essentially on drums, there several local waste processing units are built, elsewhere decommissioned facilities are cut in small bits to fit into small containers by far less efficient. The present paper proposes to illustrate how integrating a transport system from the start may influence operational choices of waste management.

2002-02-28

428

Energy-Smart Building Choices: How School Facilities Managers and Business Officials Are Reducing Operating Costs and Saving Money

A #gamma##gamma# collider would extend and complement the physics capability of a linear collider; e.g. it would be suitable for direct measurement of the partial decay width of a Higgs boson into two gamma quanta. This paper discusses choice of laser parameters, luminosity optimization, electron and laser parameters for a gamma- gamma collider as a second interaction region for the Next Linear Collider, laser path, and the lasers. It is concluded that a gamma- gamma collider is technically feasible; however it will require a significant investment in preparatory R ampersand D.

1996-08-25

429

Embedding Forensic Capabilities into Networks: Addressing Inefficiencies in Digital Forensics Investigations

Most K-12 schools could save 25% of their energy costs by being smart about energy. Nationwide, the savings potential is $6 billion. While improving energy use in buildings and busses, schools are likely to create better places for teaching and learning, with better lighting, temperature control, acoustics, and air quality. This brochure, targeted to school facilities managers and business officials, describes how schools can become more energy efficient.

2001-08-06

430

Contribution to the compensation of extra high voltage transmission lines

A typical incident response pits technicians against networks that aren't prepared forensically. [1, 2] If practitioners do consider collecting network forensic data, they face a choice between expending extraordinary effort (time and money) collecting forensically sound data, or simply restoring the network as quickly as possible. In this context, the concept of organizational network forensic readiness has emerged. This paper proposes a methodology for "operationalizing" organizational network forensic readiness. The methodology, and the theoretical analysis that led to its development, are offered as a conceptual framework for thinking about more efficient, proactive approaches to digital forensics on networks.

2006-08-01

431

Computer tomographic demonstration of so-called azygos continuation in the absence of the hepatic segment of the inferior vena cava

An improved method to design suitable compensating schemes for extra high voltage transmission lines is presented. The technique is general and effective and will greatly facilitate the design of the optimal compensation scheme for extra high voltage transmission lines. The technique is illustrated for a typical 500 kV system. The equations developed here for voltage maxima and minima along the transmission line eliminate the need for point-to-point computation of the voltage profile. The controversy existing in the literature over the problem of making a choice between pi and tee configurations has been removed and it is established with a mathematical proof that the tee configuration requires compensating elements of lower ratings.

1987-04-01

432

Computed Tomography of the cranio-cervical junction in rhematoid arthritis

Dilatation of the azygos vein is usually due to increased pressure or flow, rarely is it diopathic. Another cause is so-called continuation of the azygos in cases of absence of the hepatic segment of the inferior vena cava. The method of choice for the investigation of azygos dilatation nowadays is computer tomotgraphy. Anomalies of the inferior vena cava can be recognised in this way unequivocally by a non-invasive method. Computer tomography frequently shows important additional abnormalities (e.g. situs inversus, polysplenia), since it demonstrates all organs situated in the plane of section. (orig.).

433

Coal and climate regulations can co-exist

Twenty rheumatoid arthritis (RA) patients with involvement of the cranio-cervical junction (CCJ) were given CT scan. In most cases the myelo-CT technique with the lumbar injection of small quantities of non-ionic contrast medium was adopted; CT easily diagnosed the horizontal and vertical dislocations on the CCJ, the bone strcture lesions and the inflammatory masses. A high frequency of medullary compressions was also found in these patients. Myelo-CT appears to be the technique of choice for the precise definition of the various factors responsible for the neurological complications found in RA of the CCJ.

1987-01-01

434

Choice of energies in gamma-absorption method for layers thickness measuring of two-layers articles

Jim Rogers, president and chief executive officer of Duke Energy Corporation, examines how coal and climate change regulations can co-exist. He addresses the need for economically sound choices for future energy needs, which is complicated by what he refers to as 'the elephant in the room'climate change. He observes that new CO{sub 2} regulations would increase the USA's cost of generating electricity over time and result in higher prices for customers, and he advocates that a gradual, economy-wide, market-based U.S. climate policy is the best option. 1 ref., 1 fig.

2006-07-15

435

Cerebral and meningeal manifestations of AIDS: Sensitivity of CT and T sub 2 -weighted MR (129 patients). Zerebrale und meningeale Manifestation des AIDS: Sensitivitaet von CT und T sub 2 -gewichteter MRT (129 Patienten)

Empirical formulae are proposed for the description of relation between optimum energies minimizing the mean-weighted error of gamma absorption measurement of the thickness of layers in two-layer products with the thickness of every layer from 30 up to 150 mm by carbon. Error of informational parameter approximation with the application of tables does not exceed 10% in case of non-accurate assessment of layers thickness not exceeding 2.5%. Generalized equation is derived which binds main parameters of the task and permits to choose optimum energies with the accuracy sufficient for practical purposes

436

Automatic fuzzy decision making system with learning for competing and connected businesses

We studied 129 AIDS patients with suspected or proved intracranial manifestations of the disease. The purpose of this study was to compare the diagnostic sensitivity of unenhanced and contrast enhanced CT and unenhanced T{sub 2}-weighted MR. Thus, in 20% of our patients MR but not CT was diagnostic. In another 20% MR provided additional diagnostic information. In conclusion, MR is recommended as the imaging modality of choice in AIDS patients with non-conclusive cranial CT. (orig./GDG).

1990-09-01

437

British Library Electronic Table of Contents (United Kingdom)

We study uncertainties surrounding competition on business networks and board games. We investigate these uncertainties using concepts of fuzzy logic and game theory. We investigate how the payoff of the players is affected by a number of factors. These include the level of connectivity or number of links, the number of competitors, possible constraints on the networks and on the boards, as well as choice of strategy adopted by competitors. We introduce one fuzzy player in the game. This player uses fuzzy rules to make strategic decisions. We introduce learning to train and analyze how the fuzzy player adapts over time during the game.

2011-01-01

438

Applications of solar heat in agriculture and industry

Application aspects of the static frequency converter system

The production of process heat for agriculture and industry is one of the applications of solar energy which is very close to economic competitivity. Solar collectors can be produced at a reasonable cost by existing industries and are used optimally through applications which present a good time correlation between energy needs and the possible production of solar heat. This article studies heat consumption in industrial and agricultural sectors, gives hints on collectors choices, rates the different projects by simulation taking into account the nature of agricultural and industrial activities and the geographical location of the projects, examines when the equipment first competes according to hypotheses made on the various energy and collectors cost.

1980-01-01

439

An off-shell I.R. regularization strategy in the analysis of collinear divergences

The use of reversible pump/turbine sets in pumped storage has created a requirement for rapid reversibility. Softstart technology, based on static frequency converters (SFC) has evolved to such an extent that it is now the best choice for serving this purpose, both from a technical and from an economic point of view. The objective of our paper is to give the owners of pumped storage plants and those persons responsible for the selection, the operation or the maintenance of the electrical equipment the necessary insight into the SFC functions, features and all other application related aspects, to facilitate their decision making process. Case studies are included.

1995-12-31

440

An investigation of the partial-assignment completion effect on students' assignment choice behavior

We present a method for the analysis of singularities of Feynman amplitudes based on the Speer sector decomposition of the Schwinger parametric integrals combined with the Mellin-Barnes transform. The sector decomposition method is described in some details. We suggest the idea of applying the method to the analysis of collinear singularities in inclusive QCD cross sections in the mass-less limit regularizing the forward amplitudes by an off-shell choice of the initial particle momenta. It is shown how the suggested strategy works in the well known case of the one loop corrections to Deep Inelastic Scattering.

2011-01-01

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441

British Library Electronic Table of Contents (United Kingdom)

This study was designed to investigate the partial assignment completion effect. Seventh-grade students were given a math assignment. After working for 5 min, they were interrupted and their partially completed assignments were collected. About 20 min later, students were given their partially completed assignment and a new, control assignment that contained the same number of equivalent problems that were incomplete on their partially completed assignment. Students were told that they would have to complete an assignment but could choose which assignment they completed. Significantly more students chose their partially completed assignment. Theoretical and applied implications and directions for future research are discussed.

2011-01-01

442

A Business Model Analysis of Telecardiology Service

British Library Electronic Table of Contents (United Kingdom)

Abstract Telecare has become an increasingly common medical service in recent years. However, new service must be close to the market and be market-driven to have a high likelihood of success. This article analyzes the business model of a telecardiology service managed by a general hospital. The methodology of the article is as follows: (1) initially it describes the elements of the service based on the ontology of the business model, (2) then it transfers these elements into the choices for business model dynamic loops and examines their validity, and (3) finally provides an empirical financial analysis of the service to assess the profit-making possibilities.

2010-01-01

443

3. Physical foundations and methodology of radionuclide X-ray fluorescence analysis

Mathematical analysis of errors resulting from choice of reference frame coordinates in measuring human joint motion

The physical foundations are described of radionuclide X-ray fluorescence analysis (RXFA) and the table shows the values of K- and L-absorption thresholds and the K- and L-line energies of elements. The calculation of the intensity of characteristic radiation during RXFA proceeds from relations derived for conventional X-ray fluorescence analysis. The choice of the radionuclide source is ruled by the nature of the analysed substance and the used detection technique. The diagram shows the areas of radionuclide sources and the energy of the fluorescence radiation of elements. The table shows the spectra of radionuclide sources suitable for the purposes of RXFA measured by semiconductor Si(Li) and Ge(Li) detectors. (ES).

1983-12-01

444

Choice of energy data in environmental assessment of the built environment

Measurements of human joint motion frequently involve the use of opto-electronic and other motion analysis systems where some type of makers are used to establish joint motion within a global reference coordinate frame. Typically, this global reference coordinate frame is chosen to be most convenient for the person carrying out the experiment in which the joint motion is measured, and Euler angles are chosen as the measure of joint motion. Results, however, may be quite arbitrary and therefore rendered meaningless if the reference frame is not properly chosen with respect to the physical joint axis. In order to make a proper choice of coordinate axes in the reference frame, one must take into consideration both the location and the orientation of die physical joint axis relative to the reference frame`s axes. In nature, joint axes can exist at any orientation and location relative to an arbitrarily chosen global reference frame. An axis that is not properly aligned ...

1995-02-01

445

Systems Biology Approach in Chlamydomonas Reveals Connections between Copper Nutrition and Multiple Metabolic Steps[C][W][OA

Life cycle oriented methods are increasingly used for environmental assessments (EAs) of the built environment. However, many assumptions are made in such assessments, potentially influencing the results and making the assessment more ambiguous. To increase the reliability of EAs, consequences of the assumptions made have to be better understood. Since energy use in the operation and maintenance phase is an important factor decisive for the overall environmental performance of a building, the purpose of this study is to investigate how the selection of heat and electricity mix affects the assessed environmental performance of buildings. It also aims to suggest how to choose heat and electricity data in EAs of the built environment in general. Applying four different modes of electricity production and two different modes of heat production in a case study of three different buildings with different technical solutions for heat and electricity supply, the study show that ...

2003-03-01

446

Radioactive contamination of fish, shellfish, and waterfowl exposed to Hanford effluents: Annual summaries, 1945--1972. Hanford Environmental Dose Reconstruction Project

In this work, we query the Chlamydomonas reinhardtii copper regulon at a whole-genome level. Our RNA-Seq data simulation and analysis pipeline validated a 2-fold cutoff and 10 RPKM (reads per kilobase of mappable length per million mapped reads) (~1 mRNA per cell) to reveal 63 CRR1 targets plus another 86 copper-responsive genes. Proteomic and immunoblot analyses captured 25% of the corresponding proteins, whose abundance was also dependent on copper nutrition, validating transcriptional regulation as a major control mechanism for copper signaling in Chlamydomonas. The impact of copper deficiency on the expression of several O2-dependent enzymes included steps in lipid modification pathways. Quantitative lipid profiles indicated increased polyunsaturation of fatty acids on thylakoid membrane digalactosyldiglycerides, indicating a global impact of copper deficiency on the photosynthetic apparatus. Discovery of a putative plastid copper chaperone and a membrane ...

2011-04-01

447

Radioactive contamination of fish, shellfish, and waterfowl exposed to Hanford effluents: Annual summaries, 1945--1972

The objective of the Hanford Environmental Dose Reconstruction Project (HEDR) is to estimate the potential radiation doses received by people living within the sphere of influence of the Hanford Site. A potential critical pathway for human radiation exposure is through the consumption of waterfowl that frequent onsite waste-water ponds or through eating of fish, shellfish, and waterfowl that reside in/on the Columbia River and its tributaries downstream of the reactors. This document summarizes information on fish, shellfish, and waterfowl radiation contamination for samples collected by Hanford monitoring personnel and offsite agencies for the period 1945 to 1972. Specific information includes the types of organisms sampled, the kinds of tissues and organs analyzed, the sampling locations, and the radionuclides reported. Some tissue concentrations are also included. We anticipate that these yearly summaries will be helpful to individuals and organizations ...

1992-07-01

448

Radioactive contamination of fish, shellfish, and waterfowl exposed to Hanford effluents: Annual summaries, 1945--1972

The objective of the Hanford Environmental Dose Reconstruction Project (HEDR) is to estimate the potential radiation doses received by people living within the sphere of influence of the Hanford Site. A potential critical pathway for human radiation exposure is through the consumption of waterfowl that frequent onsite waste-water ponds or through eating of fish, shellfish, and waterfowl that reside in/on the Columbia River and its tributaries downstream of the reactors. This document summarizes information on fish, shellfish, and waterfowl radiation contamination for samples collected by Hanford monitoring personnel and offsite agencies for the period 1945 to 1972. Specific information includes the types of organisms sampled, the kinds of tissues and organs analyzed, the sampling locations, and the radionuclides reported. Some tissue concentrations are also included. We anticipate that these yearly summaries will be helpful to individuals and organizations ...

1992-07-01

449

Putative intermediates in the nerve cell differentiation pathway in hydra have properties of multipotent stem cells

The objective of the Hanford Environmental Dose Reconstruction Project (HEDR) is to estimate the potential radiation doses received by people living within the sphere of influence of the Hanford Site. A potential critical pathway for human radiation exposure is through the consumption of waterfowl that frequent onsite waste-water ponds or through eating of fish, shellfish, and waterfowl that reside in/on the Columbia River and its tributaries downstream of the reactors. This document summarizes information on fish, shellfish, and waterfowl radiation contamination for samples collected by Hanford monitoring personnel and offsite agencies for the period 1945 to 1972. Specific information includes the types of organisms sampled, the kinds of tissues and organs analyzed, the sampling locations, and the radionuclides reported. Some tissue concentrations are also included. We anticipate that these yearly summaries will be helpful to individuals and organizations ...

450

OSCAAR calculations for the Iput dose reconstruction scenario of BIOMASS theme 2

We have investigated the properties of nerve cell precursors in hydra by analyzing the differentiation and proliferation capacity of interstitial cells in the peduncle of Hydra oligactis, which is a region of active nerve cell differentiation. Our results indicate that about 50% of the interstitial cells in the peduncle can grow rapidly and also give rise to nematocyte precursors when transplanted into a gastric environment. If these cells were committed nerve cell precursors, one would not expect them to differentiate into nematocytes nor to proliferate apparently without limit. Therefore we conclude that cycling interstitial cells in peduncles are not intermediates in the nerve cell differentiation pathway but are stem cells. The remaining interstitial cells in the peduncle are in G1 and have the properties of committed nerve cell precursors. Thus, the interstitial cell population in the peduncle contains both stem cells and noncycling nerve precursors. The ...

1990-12-01

451

Multi-unit Inertial Fusion Energy (IFE) plants producing hydrogen fuel

This report presents the results obtained from the application of the accident consequence assessment code, called OSCAAR, developed in Japan Atomic Energy Research Institute to the Iput dose reconstruction scenario of BIOMASS Theme 2 organized by International Atomic Energy Agency. The Iput Scenario deals with {sup 137}Cs contamination of the catchment basin and agricultural area in the Bryansk Region of Russia, which was heavily contaminated after the Chernobyl accident. This exercise was used to test the chronic exposure pathway models in OSCAAR with actual measurements and to identify the most important sources of uncertainly with respect to each part of the assessment. The OSCAAR chronic exposure pathway models almost successfully reconstructed the whole 10-year time course of {sup 137}Cs activity concentrations in most requested types of agricultural products and natural foodstuffs. Modeling of {sup 137}Cs downward migration in soils is, ...

2001-01-01

452

Inverse spinel materials. A new class of high voltage cathode materials for Li-ion batteries

A quantitative energy pathway comparison is made between a modern oil refinery and genetic fusion hydrogen plant supporting hybrid-electric cars powered by gasoline and hydrogen-optimized internal combustion engines, respectively, both meeting President Clinton's goal for advanced car goal of 80 mpg gasoline equivalent. The comparison shows that a fusion electric plant producing hydrogen by water electrolysis at 80% efficiency must have an electric capacity of 10 GWe to support as many hydrogen-powered hybrid cars as one modern 200,000 bbl/day-capacity oil refinery could support in gasoline-powered hybrid cars. A 10 GWe fusion electric plant capital cost is limited to 12.5 B$ to produce electricity at 2.3 cents/kWehr, and hydrogen production by electrolysis at 8 $/GJ, for equal consumer fuel cost per passenger mile as in the oil-gasoline-hybrid pathway.

1994-06-20

453

Human tissue factor pathway inhibitor (TFPI) gene: Complete genomic structure and localization on the genetic map of chromosome 2q

The influence of Cr on the structure and electrochemical properties of LiCoVO{sub 4} was studied using X-Ray diffraction, scanning electron microscopy, Raman Spectroscopy and cycle tests. Doping levels up to 10 mol% were achieved, which improved the electrochemical stability of the structure of LiCoVO{sub 4}, resulting in a significant increase in the initial charge and discharge capacity. The Raman spectroscopy data for the Cr-doped LiCoVO{sub 4} is similar as for LiCoVO{sub 4}. The replacement of a dopant for the Co-ion in the inverse spinel structure causes several Raman shifts. The X-ray diffraction patterns show no new phases and combined with the Raman spectroscopy data it is concluded that the Cr dopant will be located at the octahedral site (16d) where they create an electronic pathway that enhances the electronic conductivity. However, the capacity dropped significantly after prolonged cycling, which is due to the diffusion of V{sup 5+} ions from the ...

2003-07-01

454

Hexene catalytic cracking over 30% sapo-34 catalyst for propylene maximization: influence of reaction conditions and reaction pathway exploration

Tissue factor pathway inhibitor (TFPI), a protease inhibitor that circulates in association with plasma lipoproteins (VLDL, LDL and HDL), helps to regulate the extrinsic blood coagulation cascade. The authors have cloned a 125-kb genomic region containing the entire human TFPI gene on six overlapping cosmids and prepared a restriction map of this contig to clarify gene structure. More than half (45 kb) of the 85-kb gene is occupied with 5[prime] noncoding elements: coding begins at exon 3. A HindIII RFLP identified with one cosmid was genotyped in the CEPH panel of 559 reference families. Linkage analysis using markers on human chromosome 2 located the TFPI gene on 2q, 36 cM proximal to D2S43(pYNZ15) and 13 cM distal to the crystalline [gamma]-polypeptide locus CRYGP1(p5G1). 31 refs., 3 figs., 3 tabs.

1993-08-01

455

Scientific Electronic Library Online (English)

Abstract in english Higher olefins are produced as a by product in a number of refinery processes and are one of the potential raw materials to produce propylene. In the present study, FCC model feed compound was considered to explore the olefin cracking features and options to enhance propylene using 30% SAPO-34 zeolite as catalyst in a micro-reactor. The superior selectivity of propylene (73 wt%) and higher total olefin selectivity was obtained over 30% SAPO-34 catalyst than over Y or ZSM- (more) 5 zeolite catalysts. The thermodynamical constraints were found to be relatively less serious in the case of 1-hexene conversion. Most of the 1-hexene follows a direct cracking pathway to give two propylene molecules, due to weak acid sites and better diffusion opportunities. The higher temperature and short residence time could also suppress the hydrogen transfer reactions. From OPE (olefins performance envelop) the products were classified as primary, secondary, or ...

2009-12-01

456

Effect of Wnt-1 inducible signaling pathway protein-2 (WISP-2/CCN5), a downstream protein of Wnt signaling, on adipocyte differentiation

British Library Electronic Table of Contents (United Kingdom)

Wnt signaling negatively regulates adipocyte differentiation, and ectopic expression of Wnt-1 in 3T3-L1 cells induces several downstream molecules of Wnt signaling, including Wnt-1 inducible signaling pathway protein (WISP)-2. In this study, we examined the role of WISP-2 in the process of adipocyte differentiation using an in vitro cell culture system. In the differentiation of 3T3-L1 cells, WISP-2 expression was observed in growing cells and declined thereafter. In the mitotic clonal expansion phase of adipocyte differentiation, WISP-2 expression was transiently down-regulated concurrently with up-regulation of CCAAT/enhancer-binding protein d expression. Treatment of 3T3-L1 cells in the differentiation medium with lithium, an activator of Wnt signaling, inhibited the differentiation pro...

2009-01-01

457

Doxycycline up-regulates the expression of IL-6 and GM-CSF via MAPK/ERK and NF-kB pathways in mouse thymic epithelial cells

British Library Electronic Table of Contents (United Kingdom)

Thymic epithelial cells (TECs) constitute a major component of the thymic stroma which provides a microenvironment critical for developing thymocytes. We have previously demonstrated that doxycycline (Dox), a tetracycline derivative, enhances the proliferation of the mouse thymic epithelial cell line 1 (MTEC1) via MAPK/ERK signal pathway. Herein we provide evidence that Dox also has profound impact on the cytokine production by MTEC1. Specifically, the expression of IL-6 and GM-CSF, both at mRNA and protein levels, was found to be increased in a time- and dose-dependent manner with the addition of Dox. Western blotting analysis revealed that treatment with Dox-induced phosphorylation of the p65 subunit of NF-kB and ERK. Notably, Dox-induced up-regulation of IL-6 and GM-CSF was largely abol...

2011-01-01

458

Data Merging for Integrated Microarray and Proteomic Analysis

Cell volume regulation in hemoglobin CC and AA erythrocytes

The functioning of even a simple system is much more complicated than the sum of its genes, proteins and metabolites. A premise of systems biology is that molecular profiling will lead to the discovery and characterization of important disease pathways. However, as multiple levels of effector pathway regulation appear to be the norm rather than the exception, a significant challenge presented by high-throughput genomics and proteomics technologies is to extract the biological implications of complex data. Thus, integration of heterogeneous types of data generated from diverse global technology platforms represents the first challenge in developing the necessary foundational databases needed for predictive modeling of cell and tissue responses. Given the apparent difficulty in defining the correspondence between gene expression and protein abundance measured in several systems to date, how do we make sense of these data and design the next ...

2006-05-10

459

ATF4 and the integrated stress response are induced by ethanol and cytochrome P450 2E1 in human hepatocytes

Swelling hemoglobin CC erythrocytes stimulates a ouabain-insensitive K flux that restores original cell volume. Studies were performed with the K analog, "8"6Rb. This volume regulatory pathway was characterized for its anion dependence, sensitivity to loop diuretics, and requirement for Na. The swelling-induced K flux was eliminated if intracellular chloride was replaced by nitrate and both swelling-activated K influx and efflux were partially inhibited by 1 mM furosemide or bumetanide. K influx in swollen hemoglobin CC cells was not diminished when Na in the incubation medium was replaced with choline, indicating Na independence of the swelling-induced flux. Identical experiments with hemoglobin AA cells also demonstrated a swelling-induced increase in K flux, but the magnitude and duration of this increase were considerably less than that seen with hemoglobin CC cells. The increased K flux in hemoglobin AA cells was likewise sensitive to anion replacement and to ...

460

British Library Electronic Table of Contents (United Kingdom)

Background & AimsMolecular mechanisms underlying alcoholic liver disease (ALD) are still not fully understood. Activating transcription factor-4 (ATF4) is the master coordinator of the integrated stress response (ISR), an adaptive pathway triggered by multiple stressors. which can promote cell death and induce metabolic dysregulation if the stress is intense or prolonged. The aim of this study was to assess the effect of alcohol on the ISR signaling pathway in human liver cells and to define the role of cytochrome P450 2E1 (CYP2E1) in this response. MethodsPrimary cultured human hepatocytes and human HepG2 cells over-expressing CYP2E1 by adenoviral infection were exposed to ethanol (25-100mM) for 8-48h. ResultsEthanol treatment of both liver cells up-regulated ATF4 as well as the pro-survi...

2011-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

461

A novel small-molecule inhibitor of NF-#kappa#B signaling

A kinetic and microautoradiographic study of sup 14 C-sucrose translocation into developing wheat grains

The inducible transcription factor NF-#kappa#B regulates divergent signaling pathways including inflammatory response and cancer development. Selective inhibitors for NF-#kappa#B signaling are potentially useful for treatment of inflammation and cancer. NF-#kappa#B is canonically activated by preferential disposal of its inhibitory protein; I#kappa#B, which suppresses the nuclear translocation of NF-#kappa#B. I#kappa#B#alpha# (a major member of I#kappa#B family proteins) is phosphorylated with an I#kappa#B kinase (IKK) and subsequently polyubiquitylated by SCF"#beta#"T"r"C"P"1 ubiquitin-ligase in the presence of E1 and E2 prior to proteasomal degradation. Here, we describe a novel inhibitor termed GS143, which suppressed I#kappa#B#alpha# ubiquitylation, but not I#kappa#B#alpha# phosphorylation, MDM2-directed p53 ubiquitylation, and proteasome activity in vitro. GS143 markedly suppressed the destruction of I#kappa#B#alpha# stimulated by TNF#alpha# and a set of ...

2008-04-18

462

Use of real-time Fourier Transform Infrared Reflectivity as an in situ monitor of YBCO film growth and processing

The kinetics of {sup 14}C-photosynthate import by developing wheat grains was followed after pulse-labeling the flag leaf with {sup 14}CO{sub 2}. Samples were collected from four successive points along the transport pathway to and within the grain: exuding aphid stylets on the peduncle, exuding grain pedicels, the grain crease tissues, and the liquid contents of the endosperm cavity. In addition, microautoradiographs were prepared of the grain crease tissues during movement of the {sup 14}C pulse into the grain. At all times, sucrose accounted for 93 to 97% of the total {sup 14}C present at all four sampling sites. The main features of the {sup 14}C kinetics could be accounted for by a simple compartmental model consisting of sucrose pools in series. Microautoradiographs of the crease tissues showed fairly uniform labeling of vascular parenchyma at all times, with a sharp gradient in labeling across the chalaza to the nucellus. Thus the principal resistance to ...

1991-05-01

463

The calculation of derived release limit on Wolsung NPPs based on reduced public dose limit

Fourier Transform Infrared (FTIR) spectroscopy has been utilized during high rate E-beam evaporation/deposition of YBa2Cu3O7 (YBCO). The results demonstrate the great utility of FTIR as an in situ monitor of YBCO deposition and processing. We detect different (amorphous/fine polycrystalline) insulating pre-existing phases to the high Tc superconducting phase which appear to have distinct reflectivity fingerprints dominated by thin film interference effects, as a function of temperature and oxygen pressure. These fingerprints reveal some of the kinetic and thermodynamic pathways during the growth of YBCO.

2007-01-01

464

Search for a Methanopyrus-proximal last universal common ancestor based on comparative-genomic analysis

According to enactment of reduced dose limit based on ICRP-60, the calculation of Derived Release Limits(DRL) on Wolsung NPPs was carried out. There are two methods of determination on DRL; that is MPC(Maximum Permissible Concentration) method and system analysis method. In order to use the system analysis method, lots of environmental data are necessary and complicated exposure pathway are considered. So we intend to apply MPC method that is sort of simple. In addition the calculated results were compared with derived release limit on Canadian nuclear power plant.

2000-10-01

465

British Library Electronic Table of Contents (United Kingdom)

The origin of life is a long-standing mystery puzzling many people. This mystery possesses not only philosophical but also important biological significance. To unveil this mystery, the searches for the root of life, or the last universal common ancestor (LUCA), based on comparative-genomic analysis have been intensively performed on rRNAs, tRNAs and proteins sequences. The current search pointed to a Methanopyrus-proximal LUCA, which opens up the reconstruction of Lucan biology and helps to delineate the evolutionary pathways.

2011-01-01

466

Osmoregulation in methanogens. Progress report, May 15, 1991--January 15, 1993

Osmoregulation in methanogens

Our major goal of our work has been to develop and use NMR techniques to study how methanogenic archaebacteria deal with osmotic stress with the hope of providing insights into increasing the salt tolerance of other cells. The project has three main sections: (i) in vivo studies of methanogens; (ii) use of {sup l3}C- and {sup l5}N- labeled potential precursors and in vitro analyses of specific label uptake for elucidation of osmolyte dynamics and biosynthetic pathways of osmolytes in these organisms, and isolation of key biosynthetic enzymes; and (iii) collaborative studies on identification of organic solutes in other methanogens.

1993-01-01

467

Numerical simulation of trace tests in atmosphere in Daya Bay nuclear power site

Our major goal of our work has been to develop and use NMR techniques to study how methanogenic archaebacteria deal with osmotic stress with the hope of providing insights into increasing the salt tolerance of other cells. The project has three main sections: (i) in vivo studies of methanogens; (ii) use of [sup l3]C- and [sup l5]N- labeled potential precursors and in vitro analyses of specific label uptake for elucidation of osmolyte dynamics and biosynthetic pathways of osmolytes in these organisms, and isolation of key biosynthetic enzymes; and (iii) collaborative studies on identification of organic solutes in other methanogens.

1993-01-01

468

Malnutrition, Gut-Microbial Interactions and Mucosal Immunity to Vaccines, 07 Nov 2011 - 11 Nov 2011, Le Meridien New Delhi, New Delhi, India - SciDe

The validation of the forecast model for early emergency response to nuclear accidents is evaluated by trace tests in atmosphere in Daya Bay nuclear power site. The simulation experiment of the Daya Bay nuclear power site shows that the particle spreading image and the time-integrated concentration distribution given by plume concentration prediction model can perform the variation of pathway of the pollutant transport, as well as the effects of topography on transport and diffusion of pollutants. The simulation of five trace tests in field shows that 59.1% of ratios between predicted results and observed results are within the range of 10, and 41% of ratios are within the range of 5 approximately. (authors)

2005-09-01

469

Inborn Errors of Metabolism Presenting in Childhood

... A better understanding of the links between nutrients, the gut microbiome and the intestinal immune system is likely to pave the way to the development of innovative approaches that target activation of specific immunological pathways for promoting the hostrsquo;s gut defense. Such knowledge should positively impact on the development of vaccine formulations and intervention strategies for improved control of enteric infections in developing countries. Registration fees # The Registration Fee is $715.00 on and before September 7, 2011. # After September 7, 2011, the ...

470

British Library Electronic Table of Contents (United Kingdom)

Abstract Neurodegenerative and neurometabolic disorders may cause significant morbidity and mortality in children. Imaging is important in early diagnosis of metabolic disorders and in determining the extent of brain injury. Especially after the development of new techniques such as diffusion-weighted magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), neuroimaging plays more important role in the diagnosis and management of these disorders. In these disorders, usually a mutation causes a clinically significant block in one or more metabolic pathways. This blockage usually results in either a deficiency of the product or in an accumulation of substrate with damage induced by either storage or toxicity. The presenting symptoms are usually nonspecific. In some of the ...

2011-01-01

471

Immunity and tolerance to infections in experimental hematopoietic transplantation

British Library Electronic Table of Contents (United Kingdom)

Resistance and tolerance are two types of host defense mechanisms that increase fitness in response to fungi. Several genetic polymorphisms in pattern recognition receptors, most remarkably Toll-like receptors (TLRs), have been described to influence resistance and tolerance to aspergillosis in distinct clinical settings. TLRs on dendritic cells pivotally contribute in determining the balance between immunopathology and protective immunity to the fungus. Epithelial cells also contribute to this balance via selected TLRs converging on indoleamine-2,3-dioxygenase (IDO). Studies in experimental hematopoietic transplantation confirmed the dichotomy of pathways leading to resistance and tolerance to the fungus providing new insights on the relative contribution of the hematopoietic/nonhematopoi...

2011-01-01

472

Corrosion issues in the long term storage of aluminum-clad spent nuclear fuels

Common envelope evolution

Approximately 8% of the spent nuclear fuel owned by the US Department of Energy is clad with aluminum alloys. The spent fuel must be either reprocessed or temporarily stored in wet or dry storage systems until a decision is made on final disposition in a repository. There are corrosion issues associated with the aluminum cladding regardless of the disposition pathway selected. This paper discusses those issues and provides data and analysis to demonstrate that control of corrosion induced degradation in aluminum clad spent fuels can be achieved through relatively simple engineering practices.

1996-03-24

473

British Library Electronic Table of Contents (United Kingdom)

The common envelope phase of binary star evolution plays a central role in many evolutionary pathways leading to the formation of compact objects in short period systems. Using three dimensional hydrodynamical computations, we review the major features of this evolutionary phase, focusing on the conditions that lead to the successful ejection of the envelope and, hence, survival of the system as a post common envelope binary. Future hydrodynamical calculations at high spatial resolution are required to delineate the regime in parameter space for which systems survive as compact binary systems from those for which the two components of the system merge into a single rapidly rotating star. Recent algorithmic developments will facilitate the attainment of this goal.

2010-01-01

474

Annual Radiological Environmental Monitoring Program Report for the Fort St. Vrain Independent Spent Fuel Storage Installation (2005)

Annual Radiological Environmental Monitoring Program Report for the Fort St. Vrain Independent Spent Fuel Storage Installation

This report presents the results of the 2003 Radiological Environmental Monitoring Program conducted in accordance with 10 CFR 72.44 for the Fort St. Vrain Independent Spent Fuel Storage Installation. A description of the facility and the monitoring program is provided. The results of monitoring the predominant radiation exposure pathway, direct radiation exposure, indicate the facility operation has not contributed to any increase in the estimated maximum potential dose commitment to the general public.

2001-02-01

475

"1H MR spectroscopy in pediatrics

This report presents the results of the 2001 Radiological Environmental Monitoring Program conducted in accordance with 10 CFR 72.44 for the Fort St. Vrain Independent Spent Fuel Storage Installation. A description of the facility and the monitoring program is provided. The results of monitoring the predominant radiation exposure pathway, direct and scattered radiation exposure, indicate the facility operation has not contributed to any increase in the estimated maximum potential dose commitment to the general public.

2002-02-01

476

Vascular filtration function in galactose-fed versus diabetic rats: The role of polyol pathway activity

Spectral appearance and concentrations of the most prominent metabolites are affected by brain development. This knowledge is essential for the detection of pathological changes in pediatric patients. This paper discusses specific conditions of MR spectroscopic examination of children and the effects of age on MR spectra quality and quantitation of the studied metabolites. Clinical examples show several diseases that are reflected in changes in "1H MR spectra due to pathological alterations in the biochemical pathways of the observed metabolites. Attention is given to the main metabolites such as N-acetylaspartate, creatine/phosphocreatine, cholines, lactate, inositol, etc.

2008-08-01

477

Weld metal as strong as base metal?; Schweisszusatzwerkstoffe koennen/muessen nicht immer die Anforderungen der Grundwerkstoffe erfuellen

These studies were undertaken to assess the effects of increased galactose (v increased glucose) metabolism via the polyol pathway on vascular filtration function in the kidneys, eyes, nerves, and aorta. Quantitative radiolabeled tracer techniques were used to assess glomerular filtration rate (GFR) and regional tissue vascular clearance of plasma 131I-bovine serum albumin (BSA) in five groups of male Sprague-Dawley rats: nondiabetic controls, streptozotocin-diabetic rats, nondiabetic rats fed a 50% galactose diet, diabetic rats treated with sorbinil (an aldose reductase inhibitor), and galactose-fed rats treated with sorbinil. Sorbinil was added to the diet to provide a daily dose of approximately .2 mmol/kg body weight. After 2 months of diabetes or galactose ingestion, albumin clearance was increased twofold to fourfold in the eye (anterior uvea, choroid, and retina), sciatic nerve, aorta, and kidney; GFR was increased approximately twofold and urinary excretion ...

1990-07-01

478

Water diffusion profile measurements in epoxy using neutron radiography

The development of new steels is always a challenge for the manufacturer of filler metals. In many cases it is obvious that some properties of the base metal cannot be fulfilled with matching filler metals. In some cases, dissimilar filler metals can solve the problem in some cases, there is no chance to meet the requirements of the base metal (for example yield strengths of new ultra high strength steels). This paper deals with different kinds of new steels and the requirements for the weld metal with examples from motor car industry (Mangan Austenite), crane (Ultra high strength steels), earthmoving machinery (Wear-resistant steels) and offshore (Supermartensitic steels). Specific problems will be discussed and best solutions will be highlighted. These examples make clear that the success of new kinds of steels in the market depends on solving the joining problems of these steels. (Abstract Copyright [2007], Wiley Periodicals, Inc.) [German] Die Entwicklung von ...

2007-07-15

479

Use of polymer conductors for welding thermoplastic materials

The diffusion characteristics of water in polymer materials have been studied for a few decades. Several methods have been developed to provide water diffusion characteristics as a function of time, temperature, pressure, or thickness of polymer. Unfortunately, most of these methods give the amount of water absorbed as a function of weight versus time at given environmental conditions. Concentration profiles of the water diffusion through the polymer have been unobtainable by these established methods. Neutron radiography is a method of non-destructive testing that has grown rapidly over the past ten years and is capable of giving these concentration profiles. Epoxy is one of the most commonly used polymers for which water diffusion information is important. In the automotive industry, epoxy is used both as a sealant and a bonder to prevent water from getting inside structures and causing corrosion. To prevent this corrosion, it is important to know the diffusion behavior of water in ...

480

The industrial application of fracture mechanics concepts discussed at the background of international standards and guidelines; Die industrielle Anwendung bruchmechanischer Konzepte vor dem Hintergrund internationaler Bewertungsvorschriften und Regelwerke

Although some polymer conductors of electricity (ex. Polyanilines) are materials known for more than 100 years, only recently have the interesting chemical, electrical and optic properties of their insulating and conducting forms been recognized. Advances made in the chemistry of polymer conductors have also led to improvements in processing them. This work studies a practical application of these materials: the use of polymer conductors for the remote welding of insulating thermoplastic polymers, using energy from microwaves for the local heating of the union. Many thermoplastics (for ex. Polyethylene) do not absorb, or absorb very little, energy from microwaves. Different conductor materials (conductor polymers, carbon nanotubes), however, heavily absorb energy from microwaves with the resulting heating. In this way the welding zone can be heated without affecting the rest of the piece. Conductor polymers (polyanilines) were synthesized chemically and they were characterized by ...

2004-11-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

481

Sulfidation-resistant alloy/cladding for internal components of coal-conversion equipment. Volume 2. Cladding development. Final report

Many features from the background for an intensified application of fracture mechanics concepts in many industries world-wide. These include requirements for a permanent increase of the level of performance of technical components and structures by the introduction of new materials, joining technologies and design principles, the problem of ageing components and life extension, an increased emphasis on non-destructive in-service inspection combined with improved NDT techniques, and also a number of failure events caused by fatigue and fracture The aim of the present paper is to give a brief state-of-the-art review on how fracture mechanics is applied in different industrial branches today. This is based on standards and guidelines in the aerospace industry, in the nuclear and fossil power generation, in the chemical and petrochemical and the pipeline industry, in civil engineering, offshore technique and other fields. Based on the review an outlook is given on a ...

2000-07-01

482

Solubility limits of #alpha#' SIAION solid solutions in the system Si,Al,Y/N,O

An Fe-19Cr-8Al-0.5Hf alloy has been roll bonded to Alloy 800 to form a protective clad material suitable for use in coal conversion atmospheres. The commercial producibility of both the Fe-19Cr-8Al-0.5Hf alloy and the clad composite has been demonstrated. The clad composite has been shown to exhibit resistance to sulfidation in high sulfur, coal gasification atmospheres low Btu for 2000 hrs at 1800/sup 0/F (1255K). The FeCrAlHf alloy must be preoxidized in the absence of sulfur to form fully protective alumina scales on all surfaces. Useful life of the composite at temperatures of 1400 to 2000/sup 0/F (1033 to 1366K) is governed by reactions at the FeCrAlHf clad alloy 800 interface. The rate of interdiffusion decreases with increasing Ni content and a high Ni alloy such as RA333 appears to be a better substrate than Alloy 800 for a FeCrAlHf composite. The mechanical properties of the clad composite have been evaluated at both ambient (tensile and bend) and elevated (tensile and creep ...

1981-12-01

483

Microstructural features of dissimilar welds between 316LN austenitic stainless steel and alloy 800

The solubility limit of #alpha#'-SiAlON solid solutions on the Si_3N_4-YN:3AlN composition join in the system Si_3N_4-YN-AlN has been determined at 1800 degrees C. The end members of these solid solutions are Y_0_._4_3Si_1_0_._7Al_1_._3N_1_6 and Y_0_._8Si_9_._6Al_2_._4N_1_6. Unit-cell dimensions of the #alpha#'-SiAlON solid solutions in the system Si,Al,Y/N,O can be expressed as follows: a_0 (Angstrom) = 7.752 + 0.045m + 0.009n, c_0 (Angstrom) = 5.620 + 0.048m + 0.009n, where the #alpha#'-SiAlON solid solution has the formula Y_xSi_1_2_-_(_m _+ _n_)Al_m_+_nN_1_6_-_nO_n. The single-phase boundary of the solid solution #alpha#'-SiAlON on the composition triangle Si_3N_4-YN:3AlN-Al;N:Al_2O_3 is delineated. The present paper also reports the phase relationships involving #alpha#'-SiAlON.

484

Liquid-metal flow in a sharp elbow in a uniform transverse magnetic field

For joining type 316LN austenitic stainless steel to modified 9Cr-1Mo steel for power plant application, a trimetallic configuration using an insert piece (such as alloy 800) of intermediate thermal coefficient of expansion (CTE) has been sometimes suggested for bridging the wide gap in CTE between the two steels. Two joints are thus involved and this paper is concerned with the weld between 316LN and alloy 800. These welds were produced using three types of filler materials: austenitic stainless steels corresponding to 316,16Cr-8Ni-2Mo, and the nickel-base Inconel 182{sup 1}. The weld fusion zones and the interfaces with the base materials were characterised in detail using light and transmission electron microscopy. The 316 and Inconel 182 weld metals solidified dendritically, while the 16-8-2(16%Cr-8%Ni-2%Mo) weld metal showed a predominantly cellular substructure. The Inconel weld metal contained a large number of inclusions when deposited from flux-coated ...

2000-11-15

485

Irradiation-assisted stress corrosion cracking of austenitic stainless steels: Recent progress and new approaches

In the self-cooling blankets of the Tokamak fusion reactor, a liquid metal, namely liquid lithium, is pumped through a system of ducts to transfer heat and capture neutrons. One of the blanket designs proposed in Argonne National Laboratory's Blanket Comparison and Selection study uses a combination of poloidal and toroidal ducts in order to maximize heat transfer while minimizing net pressure drop. In the design, the poloidal and toroidal ducts meet at sharp, abrupt corners. They were modelled as two identical, straight, semi-infinite, thin-walled, rectangular ducts with 45{degree} miters and joined at a 90{degree} angle in the plane of a strong, uniform magnetic field. While in the toroidal containment vessel (i.e. the blanket), the liquid lithium is subjected to a large electromagnetic body force due to the presence of a strong magnetic field. This body force so dominates the flow as to make the inertial and viscous forces negligible everywhere, except ...

1989-01-01

486

Innovative forming and fabrication technologies : new opportunities.

Irradiation-assisted stress corrosion cracking (IASCC) of several types of BWR field components fabricated from solution-annealed austenitic stainless steels (SSs), including a core internal weld, were investigated by means of slow-strain-rate test (SSRT), scanning electron microscopy (SEM), Auger electron spectroscopy (AES), and field-emission-gun advanced analytical electron microscopy (FEG-AAEM). Based on the results of the tests and analyses, separate effects of neutron fluence, tensile properties, alloying elements and major impurities identified in the American Society for Testing and Materials (ASTM) specifications, minor impurities, water chemistry, and fabrication-related variables were determined. The results indicate strongly that minor impurities not specified by the ASTM-specifications play important roles, probably through a complex synergism with grain-boundary Cr depletion. These impurities, typically associated with steelmaking and component fabrication processes, are ...

1996-09-01

487

Innovative approach for restoring coastal wetlands using treated drill cuttings

The advent of light metal alloys and advanced materials (polymer, composites, etc.) have brought the possibility of achieving important energy reductions into the full life cycle of these materials, especially in transportation applications. 1 These materials have gained acceptance in the aerospace industry but use of light metal alloys needs to gain wider acceptance in other commercial transportation areas. Among the main reasons for the relatively low use of these materials are the lack of manufacturability, insufficient mechanical properties, and increased material costs due to processing inefficiencies. Considering the enormous potential energy savings associated with the use of light metal alloys and advanced materials in transportation, there is a need to identify R&D opportunities in the fields of materials fabrication and forming aimed at developing materials with high specific mechanical properties combined with energy efficient processes and good manufacturability. ...

2008-01-31

488

Fabrication and testing of small scale mock-ups of ITER shielding blanket

The leading environmental problem facing coastal Louisiana regions is the loss of wetlands. Oil and gas exploration and production activities have contributed to wetland damage through erosion at numerous sites where canals have been cut through the marsh to access drilling sites. An independent oil and gas producer, working with Southeastern Louisiana University and two oil field service companies, developed a process to stabilize drill cuttings so that they could be used as a substrate to grow wetlands vegetation. The U.S. Department of Energy (DOE) funded a project under which the process would be validated through laboratory studies and field demonstrations. The laboratory studies demonstrated that treated drill cuttings support the growth of wetlands vegetation. However, neither the Army Corps of Engineers (COE) nor the U.S. Environmental Protection Agency (EPA) would grant regulatory approval for afield trial of the process. Argonne National Laboratory was asked to ...

1999-11-02

489

FY 1997 report on the survey of potential impacts of enlarging ASEAN on political and economic systems in South East Asia; 1997 nendo chosa hokokusho (ASEAN kakudai no Higashi Asia no seiji keizai chitsujo eno eikyo chosa)

Small scale mock-ups of the primary first wall, the baffle first wall, the shield block and a partial model for the edge of the primary first wall module were designed and fabricated incorporating most of the key design features of the ITER shielding blanket. All mock-ups featured the DSCu heat sink, the built-in SS coolant tubes within the heat sink and the SS shield block. CFC tiles was used as the protection armor for the baffle first wall mock-up. The small scale shield block mock-up, integrated with the first wall, was designed to have a poloidal curvature specified in the ITER design. Fabrication routes of mock-ups were decided based on the single step solid HIP of DSCu/DSCu, DSCu/SS and SS/SS reflecting the results of previous joining techniques development and testing. For attaching the CFC tiles onto DSCu heat sink in the fabrication of the baffle first wall mock-up, a two-step brazing was tried. All mock-ups and the partial model were successfully ...

1998-09-01

490

FPSOs assuming key role in harsh environments

This report surveys potential impacts of ASEAN (Association of South East Asian Nations) on inter-ASEAN affairs and its external relations when ASEAN will enlarge its members to include all nations in South East Asia, and thus fully represent the region. For this purpose, the survey was conducted on Vietnam, Myanmar, Laos and Cambodia, which joined in 1995, from the viewpoint of their economic and political system, and their relations with other member countries. The nature of ASEAN has gradually transformed, in which all the countries in the region have increased and internal economic issues have been tackled. It has an aim to stimulate inter-ASEAN trade and induce foreign direct investment into ASEAN as a whole by reducing import duties on intra-ASEAN trade. Underlying in these, new development is a concern about growing economic and military power of China. ASEAN solidarity will work an leverage against China should change toward worse, and ASEAN will function ...

1998-03-01

491

An ultraviolet-inducible adenosine-adenosine cross-link reflects the catalytic structure of the Tetrahymena ribozyme

There are at present 116 floating production systems and 60 storage vessels dotting the oceans involved in hydrocarbon exploration and production activities. Although concentrated mostly in the North Sea, they can be found also off the coast of Australia, eastern Canada, Brazil, some African nations and the Gulf of Mexico. They range from converted tankers to purpose built rigs. The most adaptable of the various systems is the floating production, storage and offloading (FPSO) vessel, first developed as a cost-effective means of developing fields in Brazil's very deep offshore areas. Still being tested and modified for work in widely different environments, FPSOs appear to have met all requirements in producing expenditure efficiencies, maximizing profits, and protecting workers. One of the most efficient and most technically advanced is a 292-metre long FPSO built for the Terra Nova Alliance by Daewoo Shipyards in South Korea. It arrived at Newfoundland's Bull Arm ...

2001-01-22

492

Activities performed within the program of Nuclear Safety Research on structural and cladding materials for innovative reactor systems able to transmute nuclear waste

When a shortened enzymatic version of the Tetrahymena self-splicing intervening sequence (IVS) RNA is placed under catalytic conditions and irradiated at 254 nm, a covalent cross-link forms with high efficiency. The position of the cross-link was mapped by using three independent methods: RNase H digestion, primer extension with reverse transcriptase, and partial hydrolysis of end-labeled RNA. The cross-link is chemically unusual in that it joins two adenosines, A57 and A95. Formation of this cross-link depends upon the identity and concentration of divalent cations present and upon heat-cool renaturation of the IVS in a manner that parallels conditions required for optimal catalytic activity. Furthermore, cross-linking requires the presence of sequences within the core structure, which is conserved among group I intervening sequences and necessary for catalytic activity. Together these correlations suggest that a common folded structure permits cross-linking and ...

1990-06-12

493

Somatic and genetic radiation exposure of the patient in digital subtraction angiography (DSA)

Full text: The transmutation of nuclear waste to reduce the burden on a geological repository is a relevant topic within the Program of Nuclear Safety Research of the Research Centre Karlsruhe. Several studies have confirmed that a high efficiency of transmutation of actinides is reached in fast neutron spectrum reactor system. Therefore, an important effort is dedicated to the study of transmutation strategies with different fast reactors and their associated technologies. Moreover, in international contexts as Generation IV International Forum (GIF) and Sustainable Nuclear Energy Technology Platform (SNETP), fast reactors are considered in the frame of sustainable development of nuclear energy and reduction of waste. The systems that are currently under investigation, in the frame of the different fuel cycle scenarios, are liquid metal cooled and gas cooled fast reactors as well as Accelerator Driven Sub-critical Transmutation devices (ADS). These innovative reactor systems, call for ...

2009-10-05

494

Solid-state fermentation of lignocellulotic materials for the production of enzymes by the white-rot fungus Trametes hirsuta in a modular bioreactor

The somatic and genetic radiation exposure of patients undergoing Digital Subtraction Angiography (DSA) and traditional Film Arteriography (FA) of cranial, cervical, thoracic and abdominal vascular territories are compared. The radiation doses absorbed within the critical organs - red bone marrow, lung, thyroid gland and female breast - and in the gonads were measured using an anthropomorphic Alderson phantom. A Somatic Dose Index was calculated in order to estimate the somatic radiation risk. The somatic radiation exposure depends upon the location of the critical organs with respect to the entrance site of the x-ray beam, and can be reduced by an appropriate choice of the angiographic projection. Under this condition, the radiation exposure of the patient during DSA can be lower than during FA. For renal DSA an a.p. projection, the use of an abdominal compression device and careful caudal shielding of the field are advocated. (orig.).

1986-01-01

495

British Library Electronic Table of Contents (United Kingdom)

Abstract Trametes hirsuta, a filamentous basidiomycete, was successfully cultivated in solid-state fermentation (SSF) on a mixture of pine wood chips and orange peel in a novel bioreactor that allows mixing of the inoculated solid material during the fermentation. Copper sulfate or xylidine (2,5-dimethylaniline) were added to enhance the production of enzymes, especially laccases. For comparison, Trametes hirsuta was also cultivated in submerged conditions. The effect of additives in SSF was low, whereas the choice of the solid material and the rotation of the reactor vessel showed a significant influence on the enzyme production. The space-time yields for the fermentations were calculated and showed that SSF on low-cost substrates can effectively produce extracellular enzymes at a suffici...

2011-01-01

496

Revegetation/rock cover for stabilization of inactive U-tailings sites

Hydrogen energy storage: hydrogen and oxygen storage subsystems

Soil placed over any sealant/barrier system can provide a protective mantle if the soil is not lost by erosion. Vegetation is an attractive choice for controlling erosion because it can provide an economic self-renewing cover that serves to reduce erosion by both wind and water. Vegetation alone, however, may not adequately stabilize the surface in extremely arid areas. In those areas, a properly designed surface treatment of rock cover, perhaps in conjunction with vegetation, may be necessary to stabilize the tailings surfaces. The objective of this program is to establish guidelines for surface stabilization that are compatible with sealant/barrier systems and that are suited to soils and climates at inactive uranium mill tailings sites. These guidelines will provide the means to estimate potential vegetation cover, potential erosion, effects of surface treatments on sealant/barrier systems, and costs of vegetation and rock covers. Methods for establishing ...

1982-02-01

497

Cyclotron produced lead-203

Hydrogen seems to possess all the characteristics to store the excess of electrical energy produced during off-peak periods. Hydrogen energy storage plants could be environmentally non-polluting, easy to place, not sensible to load variation, unbounded in size, efficient and safe. These last two features seem to contradict one another. An option that could give a reliable solution is the storage of hydrogen in metal hydride and the storage of oxygen as a liquid. Such a choice is probably the safest one to make and allows the achievement of efficiencies comparable to those obtainable with gaseous storage of both electrolytic products. The power consumption for H{sub 2} and O{sub 2} storage is only 3% of the total energy stored and the charging ratio approaches the values obtained with hydro-pumped storage plants. (Author)

1997-12-31

498

Application of drive systems for mine haulage systems

The radioactive isotopes of lead are reviewed with respect to their choice for in vitro tracer studies. The #gamma#-photon energy and absence of particle emission in the decay of "2"0"3Pb makes it particularly suitable for these applications. Reaction yields of "2"0"3Pb using "2"0"3Tl targets and proton, deuteron, "3He and "4He beams are listed. Using the preferred reaction "2"0"3Tl (d, 2n)"2"0"3Pb with a 15 MeV deuteron beam, yields of about 75 #mu#Ci #mu#Ahr"-"1, after chemical separation, are reported. Details of target design and chemical separation are given. (U.K.).

499