WorldWideScience
1

Guidelines for the Management of Soft Tissue Sarcomas  

UK PubMed Central (United Kingdom)

These guidelines were drawn up following a consensus meeting of UK sarcoma specialists convened under the auspices of the British Sarcoma Group and are intended to provide a framework for the multidisciplinary...Full Text Available

2010-01-01

2

Multidisciplinary management of Ewing's sarcoma : a pragmatic approach  

International Nuclear Information System (INIS)

Treatment of Ewing's sarcoma by radiotherapy, chemotherapy and surgery singly and in combination is reviewed.(M.G.B.).

5

Radiotherapy in the management of Kaposi's sarcoma: comparison of 8 Gy versus 6 Gy.  

UK PubMed Central (United Kingdom)

OBJECTIVE: To evaluate prospectively the efficacy of a single fraction of high-dose radiotherapy in patients with Kaposi's sarcoma. PATIENTS: Between 1994 and 2004, 47 patients with Kaposi's sarcoma...Full Text Available

2006-07-01

6

Kaposi's sarcoma involving the thyroid in a patient with AIDS  

International Nuclear Information System (INIS)

A 30-year-old man with acquired immune deficiency syndrome (AIDS) and Kaposi's sarcoma had a palpable thyroid mass and cervical lymphadenopathy. Nuclear medicine and ultrasound scans revealed multiple thyroid nodules. Results of biopsy showed Kaposi's sarcoma metastatic to the thyroid.

7

Immune-Based Therapies for Sarcoma  

UK PubMed Central (United Kingdom)

Immunotherapy has shown promise in a number of tumor types, but its exact role in sarcoma remains to be defined. Advanced bone and soft tissue sarcomas are challenging diseases to treat with an unmet...Full Text Available

2011-01-01

8

Four year experience of sarcoma of soft tissues and bones in a tertiary care hospital and review of literature  

UK PubMed Central (United Kingdom)

BackgroundSarcoma encompasses an uncommon group of cancer and the data is insufficient from Pakistan. We report our four years experience of Sarcoma of soft tissues and bones.MethodsThis...Full Text Available

9

Ewing's sarcoma: a neuroectodermal tumor of the chest wall  

International Nuclear Information System (INIS)

Ewing's sarcoma is the second most common malignant bone tumor in children and young adults. It is most prevalent between the ages of 10 and 15 years. There are present two cases of Ewing's sarcoma of the chest wall. The clinical, radiological and pathological features are described and the therapeutic options are discussed. (Author)

10

Diagnosis of Ewing's sarcoma in the thoracic spine - problems in differential diagnosis  

International Nuclear Information System (INIS)

Spinal Ewing's sarcomas are rare and cause problems in differential diagnosis. The radiologic, nuclear medicine and CT findings in two children with histologically proven Ewing's sarcoma are presented and problems in differential diagnosis discussed. Biopsy should be done early. (orig.).

11

Bilateral parietal extradural metastatic ewing's sarcoma simulating acute epidural hematoma  

International Nuclear Information System (INIS)

Sarcomas usually metastasize to lugs. The following case report describes an unusual metastasis of Ewing's sarcoma to extradural parietal region bilaterally. The primary was found at lower end of ulna. (author)

2006-08-01

12

Bone scanning in Ewing's sarcoma  

International Nuclear Information System (INIS)

In eight patients with Ewing's sarcoma bone scans were performed using "9"9"mTc-MDP. This procedure rendered possible the diagnosis of clinically or radiologically silent metastases. (orig.).

14

EMS and evaluation of environmental aspects: a review  

International Nuclear Information System (INIS)

The Environmental Management System (EMS) is an instrument to manage the interaction between the organization and the environment. The scope od EMS is to reduce the environmental impact and to achieve improvements in overall performances. In particular, the focus point of EMS implementation is the method for identifying and assessing significant environmental aspects. This paper presents a review of methods and techniques existing in this area, and the definition of the state of the art. The results of the literature, regulation and case studies reviews have shown that rigorous, repeatable and transparent methodologies do not exist.

2006-04-01

17

Intracranial Dural Metastasis of Ewing's Sarcoma: a Case Report  

International Nuclear Information System (INIS)

Ewing's sarcoma is a malignant bone tumor that can occur anywhere in the body, but it is most commonly observed in the long bones of the arms and legs, the pelvis and in the chest. The predominant sites of metastasis include the lung (38%), bone (including the spine; 31%), and the bone marrow (11%). Metastasis of Ewing's sarcoma to the central nervous system (CNS) is relatively rare, and most of the previous reports have demonstrated involvement of the bony calvarium or brain parenchyma. We describe here the imaging findings of dural metastasis of Ewing's sarcoma, and these imaging findings have not been previously reported on in the medical literature. In conclusion, dural metastasis of Ewing's sarcoma is very rare and its imaging characteristics are similar to those of a primary tumor, which mimic the findings of a schwannoma or meningioma. Despite its rarity, secondary Ewing's ...

2008-02-01

18

Treatment of early uterine sarcomas: disentangling adjuvant modalities  

UK PubMed Central (United Kingdom)

Uterine sarcomas are a rare group of neoplasms with aggressive clinical course and poor prognosis. They are classified into four main histological subtypes in order of decreasing incidence: carcinosarcomas,...Full Text Available

19

Resection of pulmonary metastases in pediatric patients with Ewing sarcoma improves survival  

UK PubMed Central (United Kingdom)

BackgroundEwing sarcoma (ES) is the second most common bone tumor in children, and survival of those with metastatic ES has not improved. Previous studies have shown...Full Text Available

2011-02-01

20

Osteogenic sarcoma of the breast arising in a cystosarcoma phyllodes: a case report and review of the literature  

UK PubMed Central (United Kingdom)

IntroductionPrimary tumors of the breast containing bone and cartilage are extremely rare, and an osteogenic sarcoma arising from a cystosarcoma phyllodes is exceptional.Case...Full Text Available

21

Late metastasis from neuroblastoma mimicking Ewing's sarcoma  

International Nuclear Information System (INIS)

The case of an unusual late metastasis of neuroblastoma to the calcaneum, appearing as a sole recurrence 9 years after surgery, is reported. The radiographic features of the osseous lesion were very suggestive of primary bone malignancy, Ewing's sarcoma as the first option, with extraosseous spread to the soft tissues. (orig.).

22

Identification of two homologs of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in retroperitoneal fibromatosis of different macaque species.  

UK PubMed Central (United Kingdom)

Simian retroperitoneal fibromatosis (RF) is a vascular fibroproliferative neoplasm which has many morphological and histological similarities to human Kaposi's sarcoma (KS). Like epidemic KS in AIDS...Full Text Available

1997-05-01

23

Extraosseous Ewing's sarcoma: review of a case  

International Nuclear Information System (INIS)

Extraosseous Ewing's sarcoma (EES) is an uncommon lesion included in the group of soft tissue tumors. We present a case in a 19-year-old woman in which the diagnosis was not initially suspected because of the absence of clinical and radiological evidence. (Author).

24

Ewing's sarcoma presenting as a solitary cyst  

International Nuclear Information System (INIS)

This case describes a 10-year-old girl who developed a Ewing's sarcoma in her proximal fibula. The radiologic features mimicked those of a unicameral bone cyst. The presence of pain and the atypical location led to a prompt biopsy and the correct diagnosis. The mechanism of this unusual radiographic presentation is discussed. (orig.)

2006-07-01

25

Ecteinascidin 743 Interferes with the Activity of EWS-FLI1 in Ewing Sarcoma Cells12  

UK PubMed Central (United Kingdom)

ET-743 (trabectedin; Yondelis) is approved in Europe for the treatment of soft tissue sarcomas. Emerging phase 1 and 2 clinical data have shown high response rates in myxoid liposarcoma in part owing...Full Text Available

2011-02-01

26

Early detection of bone metastases of Ewing's sarcoma by magnetic resonance imaging  

International Nuclear Information System (INIS)

Bone metastases of an Ewing's sarcoma were detected by magnetic resonance imaging (MRI), when bone scan, CT and plain films were still normal. This is due to the ability of MRI to detect intramedullary metastases before involvement of the cortex. (Auth.).

27

Current Therapeutic Approaches in Metastatic and Recurrent Ewing Sarcoma  

UK PubMed Central (United Kingdom)

Ewing sarcoma (ES) is the second most common type of primary bone malignancy in children and young adults. Survival rates for localized ES have improved to upwards of 70% with aggressive chemotherapy...Full Text Available

2011-01-01

28

Copy Number Alterations and Methylation in Ewing's Sarcoma  

UK PubMed Central (United Kingdom)

Ewing's sarcoma is the second most common bone malignancy affecting children and young adults. The prognosis is especially poor in metastatic or relapsed disease. The cell of origin remains elusive,...Full Text Available

2011-01-01

29

Chest Wall Resection for Adult Soft Tissue Sarcomas and Chondrosarcomas: Analysis of Prognostic Factors  

UK PubMed Central (United Kingdom)

BackgroundWide resection with tumor-free margins is necessary in soft-tissue sarcomas to minimize local recurrence and to contribute to long-term survival. Information about treatment...Full Text Available

2011-01-01

30

Characterization of Two Divergent Lineages of Macaque Rhadinoviruses Related to Kaposi's Sarcoma-Associated Herpesvirus  

UK PubMed Central (United Kingdom)

We have cloned and characterized the entire DNA polymerase gene and flanking regions from Kaposi's sarcoma-associated herpesvirus (KSHV) and two closely related macaque homologs of KSHV, retroperitoneal...Full Text Available

2000-05-01

31

Therapy of children with Ewing's sarcoma  

International Nuclear Information System (INIS)

Combined treatment of 131 patients aged 3-16 with local form of Ewing's sarcoma is carried out. Survival rate per year was studied in patients without diagnosed metastases depending on chemiotherapy method. It is stated that improved results of treatment of children with Ewing's sarcoma may be achieved by combining radiotherapy with long-term systemic polychemotherapy. The most efficient and expedient method of radiotherapy of long bone sarcoma in children is dialy three-field irradiation with 2 Gy at SFD to the tumor 60 Gy, and adjacent tissues - 40 Gy.

34

The results of treatment of localized Ewing's sarcoma and reticulosarcoma in pediatric patients  

International Nuclear Information System (INIS)

The results of treatment of 53 cases of pediatric localized Ewing's sarcoma and bone reticulosarcoma were analized. Chemoradiotherapy is a procerdure of choice in bone marrow sarcoma treatment: while overall five-year survival was 28.4#+-#6.2%, it was as high as 64.9% in cases of combined treatment (total focal dose of at least 50 Gy+polychemotherapy). Two cases of osteo- and chondrosarcoma development in exposed bone are described.

35

Some features of chemoradiopathomorphosis of Ewing's sarcoma and reticulum cell sarcoma  

International Nuclear Information System (INIS)

The paper is concerned with the results of a morphological study following chemoradiotherapy in 25 patients with Ewing's sarcoma and 14 patients with reticulum cell carcoma. The signs of therapeutic pathomophosis were observed in the first 3 days, and substitution of the connective tissue for a necrotized tumor started by the 3rd-4th week after the initiation of therapy. In some cases tumor growth and recurrences at the site of a treated tumor were observed.

36

Needle aspiration biopsy in the diagnosis of lytic bone lesions in histiocytosis X, Ewing's sarcoma and neuroblastoma  

International Nuclear Information System (INIS)

Cytologic smears obtained by needle aspiration biopsy of lytic bone lesions in 15 patients with histiocytosis X, Ewing's sarcoma and neuroblastoma were reviewed. After conventional staining, histiocytosis X could be diagnosed and differentiated from small cell tumours such as Ewing's sarcoma and neuroblastoma. The need for sampling material for cytochemical and ultrastructural analysis of these small cell tumours by needle aspiration is emphasized. (Auth.).

37

MR findings of primary Ewing's sarcoma of greater wing of sphenoid  

International Nuclear Information System (INIS)

Primary Ewing's sarcoma of the skull is a very rare entity. We report MRI findings in a case of Ewing's sarcoma of the greater wing of sphenoid in a 4-year-old patient. Magnetic resonance imaging showed markedly heterogenous signal intensity with areas of haemorrhage and necrosis. It also demonstrated the exact extent of tumour due to its multiplanar capabilities and was, therefore, helpful in planning surgery. Copyright (2002) Blackwell Science Pty Ltd

2002-12-01

38

Ewing's sarcoma of the sacrum  

International Nuclear Information System (INIS)

A lytic lesion with softtissue extension in the sacrum of a 47-year old man was needle-biopsied under computed tomographic (CT) guidance using an 18-gauge cutting needle. The cytologic appearance of the lesion and immunohistochemical staining were diagnostic of Ewing's sarcoma. Specifically, a new marker (O13) for the presence of glycoprotein p30/32 mic2 in Ewing's sarcoma was utilized. (orig.).

39

Brain and bone scans in primary Ewing's sarcoma of the petrous bone: case report  

International Nuclear Information System (INIS)

The authors present a case in which primary Ewing's sarcoma of the right petrous pyramid in a 9-year-old girl showed no uptake on a /sup 99m/Tc-pertechnetate nuclide angiogram. Intense uptake was present on a /sup 99m/Tc-polyphosphate bone scan, but a static brain scan was only minimally abnormal. The diagnosis and treatment of Ewing's sarcoma are reviewed.

40

Bone scintigraphy in Ewing's sarcoma during and after treatment - prognostic information from the primary tumor site  

International Nuclear Information System (INIS)

A bone scan can be negative in Ewing's sarcoma. The bone scan during and after treatment can give prognostic information on the primary tumor site: A persisting hot spot strongly suggests the presence of local malignancy, while a hot spot becomming negative points to local cure of Ewing's sarcoma. (orig.).

41

Numerical field calculations considering the human subject for engineering and safety assurance in MRI  

UK PubMed Central (United Kingdom)

Numerical calculations of static, switched, and radiofrequency (RF) electromagnetic (EM) fields considering the geometry and EM properties of the human body are used increasingly in MRI to explain...Full Text Available

2009-11-01

42

Radiographic features of Ewing's sarcoma of the bones of the hands and feet  

International Nuclear Information System (INIS)

The radiographic features of Ewing's sarcoma of the bones of the hands and feet are reviewed utilizing cases obtained from the Mayo Clinic patient files and the consultation files of Drs. D.C. Dahlin and K.K. Unni. This series consists of a total of 43 cases of pathologically proven Ewing's sarcoma involving the small bones of the hands and feet. The classic radiographic features of Ewing's sarcoma in the long bones, including lytic, permeative destruction, aggressive periosteal reaction, cortical violation, and a soft tissue mass, are also seen in the bones of the hands and feet, with similar frequency. These classic features are most commonly present in lesions affecting the short tubular bones. Lesions affecting the tarsal bones more often demonstrate atypical radiographic features. These atypical radiographic appearances may play a role in the reported delay in diagnosis of Ewing's sarcoma within ...

2001-03-01

43

Incidence and management of secondary malignancies in patients with retinoblastoma and Ewing's sarcoma  

International Nuclear Information System (INIS)

Childhood cancer survivors at highest risk of developing a secondary malignancy are those with hereditary retinoblastoma. The majority of such secondary cancers will be sarcomas, most commonly of bone. One-third of these occur outside a typical radiation field, commonly in an extremity. Bone sarcoma is also the most commonly reported secondary cancer to develop among survivors of Ewing's sarcoma. In this group, radiation doses greater than 60 Gy as well as alkylating agent chemotherapy have been identified as contributors to the increased risk. The prognosis for patients with a secondary sarcoma has been poor, with few cures reported to date. However, an aggressive, combined modality approach, including radical resection, postoperative radiation, and adjuvant chemotherapy, may improve the survival rate.

44

Actuarial risk of isolated CNS involvement in Ewing's sarcoma following prophylactic cranial irradiation and intrathecal methotrexate  

International Nuclear Information System (INIS)

Records of 154 patients with Ewing's sarcoma treated at the National Cancer Institute were reviewed to assess the incidence and risk of developing isolated central nervous system (CNS) Ewing's sarcoma. Sixty-two of the 154 patients had received CNS irradiation and intrathecal (i.t.) methotrexate as part of their initial therapy to prevent the occurrence of isolated CNS Ewing's sarcoma. The risk of developing isolate CNS Ewing's sarcoma was greatest within the first two years after diagnosis and was approximately 10%. The overall risk of CNS recurrence in the group of patients receiving DNS treatment was similar to the group receiving no therapy directed to the CNS. The occurrence of isolated CNS involvement was not prevented by the use of CNS irradiation and i.t. methotrexate. Because of a lack of efficacy to the CNS irradiation regimen, current treatment regimens do not include therapy directed to CNS.

48

Imaging Ewing's sarcoma  

International Nuclear Information System (INIS)

Ewing's sarcoma is a highly malignant neoplasm of the bone whose origin is still uncertain. A strong relationship exists between Ewing's sarcoma and tumors of neural origin (Ewing family of tumors). Ewing's sarcoma must be distinguished from other round-cell tumors like lymphoma and neuroblastoma and also must be differentiated from osteogenic sarcomas. On plain radiographs, Ewing's sarcoma appears as a lytic or mixed lytic-sclerotic, rarely as predominantly sclerotic lesion with margins Lodwick grade III. It is located primarily in the diaphyseal and metadiaphyseal regions of the long bones of the lower extremities. A large soft tissue tumor is usually present. Magnetic resonance imaging is the imaging modality of choice to evaluate the extent of the primary lesion, to monitor the response to neoadjuvant chemotherapy and to follow up non-resected Ewing's ...

1998-06-01

49

Aggressive Ewing's sarcoma appearing as a cold lesion on bone scan  

International Nuclear Information System (INIS)

Ewing's sarcoma classically presents as a hot spot on bone scan as a result of increased vascularity of the tumor and new bone formation. Purpose We report and analyze an uncommon pattern of a 'cold' lesion in Ewing's sarcoma on bone scan and its pathophysiologic significance. Case report A 15-year-old boy complaining of thigh pain. CT scan evoked Ewing's sarcoma or osteitis. MRI evoked chronic osteitis. Scintigraphy showed a fairly intense and heterogeneous uptake on the femoral lesion and no abnormal uptake elsewhere. Biopsy showed none pathologic pattern. Three months later, a second biopsy concluded to Ewing's sarcoma. Bone scan showed a larger lesion with peripheral intense uptake centered by enlarged 'cold' area in the left femoral diaphysis and no evident bone metastasis. The patient underwent chemotherapy and surgery. Three months later, bone scan showed extensive skeletal metastasis. Conclusion ...

2009-10-01

50

Integrating the Integrators - A Roadmap to Success  

Energy Technology Data Exchange (ETDEWEB)

The U.S. Department of Energy Environmental Management's (DOE-EM) investments in science and technology, as well as science and technology investments associated with other parts of the DOE are aimed at meeting the Departments cleanup goals. These investments, primarily focused on EM's cleanup mission, comprise the Environmental Quality Research and Development (R&D) portfolios. Synchronizing EM's Cleanup Project Managers (operations facility and process owners throughout the DOE complex) operational needs with EM R&D including the extensive work of the six Focus Areas (major thrust areas within DOE-EM) has been a continuing challenge. This recent initiative to better integrate the R&D program is in response to evolving needs within the Department to apply proven system engineering methods to clarify requirements and define ...

1999-03-01

51

The course, diagnosis and treatment of Ewing's sarcoma of the rib in children  

International Nuclear Information System (INIS)

Advances in the diagnosis of Ewing's sarcoma of the rib were considered and retrospective analysis of the treatment of 32 patients (76% of them were children at the age of 10-15 y.o.) in the clinic of children oncology was performed. It was shown that the diagnosis of Ewing's sarcoma of the rib in children ought to be combined taking into account the course, morphology and radiation examination techniques. Most optimum treatment consisted of combined therapy (cyclic polychemotherapy, lesion focus irradiation at the summary focus dose of 57 Gy, surgery with subsequent polychemotherapy for not less than 1.5 years

1997-11-18

52

Periosteal Ewing's sarcoma  

International Nuclear Information System (INIS)

Periosteal Ewing's sarcoma is an uncommon, but well documented origin of this malignant condition with radiography signs, different from intramedullary growing tumours. Imaging modalities like CT or MRI supply proof of macroscopically intact endosteal cortical surface and free medullary cavity in long bones affected by this periosteal type of malignancy. Definite confirmation is valid after a careful microscopic investigation of the resected specimen. The prognosis of this type of Ewing's sarcoma may be favourable than that of the central type. Early diagnosis and therapy are thus essential. A clinical survey of six observations is given. (orig.).

53

Computed tomography in the evaluation of 41 cases of Ewing's sarcoma  

International Nuclear Information System (INIS)

Computed tomography (CT) has already proved extremely effective both in cerebral and abdominal pathology. Several recent publications describing first heterogeneous series [1, 2, 7, 11-17], then studies of a single type of lesion [3-6, 8] have illustrated its usefulness in the study of bone lesions. This report deals with 41 cases of Ewing's sarcoma studied by CT at the Institut Gustave Roussy from October 1977 to July 1981, and tries to show both the limitations and indications of this technique for the diagnosis, treatment, and follow-up of Ewing's sarcoma as well as in the diagnosis of any eventual recurrence. (orig.).

54

Acute lymphoblastic leukemia with multiple cytogenetic abnormalities secondary to treatment of Ewing's sarcoma  

International Nuclear Information System (INIS)

We report the case of a 22-year-old man with Ewing's sarcoma who attained a complete remission (CR) after combination radiotherapy and chemotherapy. Secondary acute lymphoblastic leukemia with multiple cytogenetic abnormalities involving chromosome 5 and 7 developed 16 years later. The patient underwent induction chemotherapy and entered a CR. Peripheral blood stem cell transplantation from a matched sibling was performed successfully and he is in complete remission of both ALL and Ewing's sarcoma. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)

1999-06-01

55

A case of Ewing's sarcoma treated successfully with chemotherapy and radiotherapy  

International Nuclear Information System (INIS)

We encountered a case of Ewing's sarcoma. The patient was a 19 year-old girl, who visited a local physician because of pain in the left scapular region, and was referred to us. Roentgenograms of her left scapula revealed an irregular moth-eaten shadow which was suspected to be a malignant bone tumor. The histological diagnosis of Ewing's sarcoma was comfirmed by needle biopsy. The initial stage of treatment consisted of radiation therapy (6000 rads) and chemotherapy (VAC and ADR). At the end of the initial stage, the symptoms were improved, the size of the local lesion was reduced on the roentgenogram and there was no evidence of distant metastases. (author).

56

Prognostic patients with value of some factors in therapy of patients with reticulosarcoma Ewing's sarcoma and solitary myeloma of pelvic bones  

International Nuclear Information System (INIS)

Effect of different factors on survival of patients with Ewing sarcoma (20 people), primary bone reticulosarcoma (43) and myeloma (10) of pelvic bones, has been studied. Independently of the method of treatment, the rate of 3-year survival from reticulosarcoma start constituted (31.5+-7.1)%, Ewing sarcoma - (33.0+-10.8)%, myeloma - (36.0+-15.9)%. Index of 5-year survival in case of reticulosarcoma constituted (20.9+-6.4)%, Ewing sarcoma - (23.6+-11.0)%, myeloma - (36.0+-15.9)%. Improvement of delayed results after prophylactic therapy courses is pointed out. Degree of pelvic bone affection is of a very important prognostic value.

57

Second malignancies after treatment for Ewing's sarcoma  

International Nuclear Information System (INIS)

Background: Some former retrospective studies have suggested that patients with Ewing's sarcoma might have a very high risk for developing secondary sarcomas if treated with radiotherapy. We have evaluated the risk of second malignancies (SM) in patients treated in the German Cooperative Ewing's Sarcoma Studies CESS 81 and CESS 86. Materials and methods: From January 1981 through June 1991, a total number of 674 patients was registered in the two multicentric Ewing's sarcoma trials CESS 81 (1981 through 1985) and CESS 86 (1986 through June 1991). The systemic treatment consisted in both studies of a four-drug-chemotherapy (VACA= vincristine, actinomycin D, cyclophosphamide and adriamycin; or VAIA= vincristine, actinomycin D, ifosfamide and adriamycin) and a total number of four courses, each lasting nine weeks, was recommended by the protocol. Local therapy was either complete surgery or surgery plus ...

58

Conceptual design of the ATLAS EM muon chamber support structures  

CERN Document Server

The conceptual design of the support structures of the EM muon chambers is presented. On each side of the detector the EM chambers are arranged in four layers: one layer of MDTs and the three layers of TGCs. The chambers are mounted on four individual wheel structures per side. The four wheels are inclined by 1.23% and suspended from two longitudinal beams parallel to the beam axis. In order to allow for the opening of the ATLAS detector the wheels can be displaced longitudinally over a distance of 6 m. In addition individual wheels can be separated from each other by up to 1 m for maintenance purposes.

1998-01-01

61

Know When to Hold`em: The Art of Restraint  

Science.gov (United States)

... Wiki Leaks (The Sunshine Press) Video, 39 min., 2010, electronic video, http://www.collateralmurder.com and http://wikileaks.org/ (accessed 11 ...

2010-05-03

63

Electron Microscope Database - GCMD - NASA  

Science.gov (United States)

Electron Microscope Database. Entry ID: em_database ... Ancillary Keywords. electron microscope. Data Set Progress. IN WORK. Originating Center ...

64

EMS and process of identification and evaluation of environmental aspects: a proposal methodology  

International Nuclear Information System (INIS)

The Environmental Management System (EMS) is an instrument to manage the interaction between the organization and the environment. The scope od EMS is to reduce the environmental impact and to achieve improvements in overall performances. In particular, the focus point of EMS implementation is the method for identifying and assessing significant environmental aspects. The results of the literature and regulation reviews (Perotto 2006) have shown that rigourous repeatable and transparent methodologies do not exist. This paper presents a proposal method for identifying and assessing significant environmental aspects, that has all three of these important characteristics. In particular, the proposal methodology for assessing aspects is based on some criteria that are combined in a specific algorithm. It is important to specify that to make a correct application of the method a preliminary rigorous approach to investigating the ...

2006-05-01

69

Use of absorbable mesh to displace bowel and avoid radiation enteropathy, during therapy of pelvic Ewing's sarcoma  

International Nuclear Information System (INIS)

The use of absorbable polyglactin 910 mesh (Vicryl) is described in a case of Ewing's sarcoma of the pelvis. An operation was performed to hold the small bowel and colon out of the pelvis for a temporary period during which radical radiotherapy was delivered. The mesh allowed the temporary displacement of bowel and obviated bowel radiation morbidity. (author).

70

Uncommon bone tumors of the skull: Ewing's sarcoma and Triton's tumor  

International Nuclear Information System (INIS)

Ewing's sarcoma and Triton's tumor are two uncommon bone tumors of the skull that have nonspecific clinical and imaging features. However, imaging methods are important in the detection of the lesions during the diagnostic investigation in order to evaluate the extent of the bone lesions, involvement of the soft tissues and brain, and to determine the presence of local recurrence and metastases. The confirmatory diagnosis relies on histological studies and immunohistochemistry. The authors report two cases of patients with these tumors and present the radiological findings. (author)

71

The value of radiotherapy in the treatment of Ewing's sarcoma in children  

International Nuclear Information System (INIS)

Results of treatment of 30 children with Ewing's sarcoma irradiated in the First Radiotherapy Department, Cancer Center, Warsaw, in the period 1983-1992, are described. In 40% of patients NED survival from 1 till 10 years and in 70% the local control was obtained, and no serious radiations equelae were observed. (author).

72

Spontaneous mutations affecting the host range of the B77 strain of avian sarcoma virus involve type-specific changes in the virion envelope antigen.  

UK PubMed Central (United Kingdom)

Previously it was shown that the host-range gene of the Bratislava strain of avain sarcoma virus (B77 virus) spontaneously mutates with a very high rate. The wild-type B77 virus called B77 virus-II,...Full Text Available

1977-01-01

73

Metastatic Ewing's sarcoma to the skull: CNS involvement excluded by MRI  

International Nuclear Information System (INIS)

A case of metastatic Ewing's sarcoma to the skull is presented, demonstrating the superiority of magnetic resonance imaging over other imaging modalities to exclude CNS involvement. Precise delineation of different tumor components in extradural location contained in an intact dural rim together with compressed cortex showing no signs of tumorous involvement constituted an MRI appearance allowing us to exclude tumor outgrowth into the brain. (orig.).

74

Is there still a place for bone scanning in Ewing's sarcoma: concise communication  

International Nuclear Information System (INIS)

In this retrospective study, 28 cases of Ewing's sarcoma are reviewed for the onset of metastasis. Bone scans demonstrated bone metastasis in three out of 28 patients at presentation. Of the 22 patients free of metastases at presentation, ten subsequently developed bone metastases. In six of these patients, the bone scan was the earliest demonstrator of metastatic disease. Bone scans are recommended at presentation and periodically during follow-up.

75

Influence of tumour volume and cell kinetics on the response of the solid Yoshida sarcoma to hyperthermia (42 degrees C).  

UK PubMed Central (United Kingdom)

The cytokinetic response of the solid Yoshida sarcoma to hyperthermia was examined at two tumour volumes, 1.0-1.5 ml and 3.0-3.5 ml. The tumour, growing on the feet of rats, was heated at 42 degrees...Full Text Available

1980-01-01

76

Ewing's sarcoma in childhood and adolescence  

International Nuclear Information System (INIS)

A review of main issues in diagnosing, complex treatment and prognosis of Ewing's sarcoma is presented. Current trend in chemotherapy, radiotherapy and surgery of the disease is discussed. Unfavourable prognosis is attributed to the systematic character of the disease, necessitating a complex therapeutic approach. Attempts to make an optimal combination of the three therapeutic methods in order to improve survival and reduce the rate of post-treatment complications are analyzed. 37 refs., 4 tabs. (author).

77

Acute myelomonocytic leukemia after irradiation and chemotherapy for Ewing's sarcoma  

International Nuclear Information System (INIS)

A case is presented in which the diagnosis of acute myelomonocytic leukemia was made 16 months after the start of irradation and chemotherapy for Ewing's sarcoma. The association of these two diseases is rare. The etiologic role of therapy in the development of leukemia is speculative in this case. However, there is need for surveillance for secondary neoplasms of all types so that the benefits of therapy may be properly weighed against the risks.

78

"9"9"mTc-tetrofosmin uptake by peripheral neuroectodermal tumor (PNET) and Ewing's sarcoma: a possible technique to differentiate one from other  

International Nuclear Information System (INIS)

"9"9"mTc-tetrofosmin has been used in the imaging of cancers of diverse origin. In this report the use of it in the family of round cell tumors, mainly Ewing's sarcoma and peripheral neuroectodermal tumor (PNET), where differentiation between the two is not always simple on the basis of histopathological features alone is discussed

1998-09-01

79

Second malignancies after treatment for Ewing's sarcoma: a report of the CESS-studies  

International Nuclear Information System (INIS)

Purpose: During recent years, more intensified systemic and local treatment regimens have increased the 5-year survival figures in localized Ewing's sarcoma to more than 60%. There is, however, concern about the risk of second malignancies (SM) in long-term survivors. We have analyzed the second malignancies in patients treated in the German Ewing's Sarcoma Studies CESS 81 and CESS 86. Materials and Methods: From January 1981 through June 1991, 674 patients were registered in the two sequential multicentric Ewing's sarcoma trials CESS 81 (recruitment period 1981-1985) and CESS 86 (1986-1991). The systemic treatment in both studies consisted of a four-drug-regimen (VACA = vincristine, actinomycin D, cyclophosphamide, and adriamycin; or VAIA = vincristine, actinomycin D, ifosfamide, and adriamycin) and a total number of four courses, each lasting nine weeks, was recommended by the protocol. Local therapy in curative patients ...

1998-09-01

80

Management of sampling and analysis activities in DOE`s Office of Environmental Management  

Energy Technology Data Exchange (ETDEWEB)

DOE`s Office of Environmental Management (EM) is responsible for managing waste and cleaning up contamination at DOE sites across the United States. A substantial fraction of the work performed for EM includes sampling and analysis activities. This paper outlines the Sample Management Programs, achievements to date, and future directions.

1995-12-31

81

Differences of the deformation parameter #beta# for 2"+_1 states of even-even spherical nuclei from electromagnetic excitation and proton scattering  

International Nuclear Information System (INIS)

Differences of the deformation parameters for the 2"+_1 states of even-even spherical nuclei extracted from electromagnetic excitation #beta#sup(em)_2 and from proton scattering #beta#sup(pp')_2 are discussed. It is found that the ratio #beta#sup(pp')_2/#beta#sup(em)_2 is equal to about unity and that there is a small isotope dependence for several incomplete shell nuclei. (orig.).

82

Radiation therapy and Ewing's sarcoma in childhood  

International Nuclear Information System (INIS)

Despite high local control rate in Ewing's sarcoma the exact indication of radiation therapy is still controversial as well as the choice of the target volume and the optimal dose of radiation. The importance of the quality of radiotherapy has been stressed in recently published data and has shown a significant impact on long term local control with adequate radiation therapy. The dramatic improvement of precision allowed by the conformal therapy and three dimensional dosimetry allow to expect a decrease of late effects expected for second malignancies. However, late sequelae and radio-induced osteosarcoma still remain the major side effects after radiotherapy. The authors discuss the results of the main trials on Ewing's sarcoma on the choice of dose and target volume. Surgery is still the preferred choice for small tumors if the foreseen outcome is identical. (authors). 28 refs.

83

Plain radiographic predictors of survival in treated Ewing's sarcoma  

International Nuclear Information System (INIS)

We analyzed 16 radiographic features of primary Ewing's sarcoma in 342 patients from the IESS 7299 (Intergroup Ewing's Sarcoma Study) for prognostic significance. Of these, 3 features demonstrated a statistically significant relationship to survival: maximal tumor dimension, tumor location, and an appearance of honeycombing within the lesion. Those individuals with primary lesions centered in the pelvis, femur, or humerus had a worse survival rate than those with lesions centered elsewhere. Similarly, we observed an inverse relationship between the greatest dimension of the osseous portion of the lesion and survival. The radiographic finding of honeycombing also showed a statistical association with improved survival. However, this feature was observed infrequently, and its significance should be assessed further. Otherwise, no other feature that we analyzed showed any relationship to patient prognosis. (orig.).

84

Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas  

British Library Electronic Table of Contents (United Kingdom)

Spindle cell sarcomas consist of tumors with different biological features, of which distant metastasis is the most ominous sign for a poor prognosis. However, metastasis is difficult to predict on the basis of current histopathological analyses. We have identified actin filament-associated protein 1-like 1 (AFAP1L1) as a candidate for a metastasis-predicting marker from the gene expression profiles of 65 spindle cell sarcomas. A multivariate analysis determined that AFAP1L1 was an independent factor for predicting the occurrence of distant metastasis (P=0.0001), which was further confirmed in another set of 41 tumors by a quantitative mRNA expression analysis. Immunohistochemical staining using paraffin-embedded tumor tissues revealed that the metastasis-free rate was significantly better...

2011-01-01

85

Ewing's sarcoma recurrence vs radiation necrosis in dynamic contrast-enhanced MR imaging: a case report  

International Nuclear Information System (INIS)

Purpose. We report a case of Ewing's sarcoma in the right distal femur in a 6-year-old male to demonstrate how dynamic contrast-enhanced magnetic resonance imaging (DEMRI) findings predicted histopathology. Materials and methods. DEMRI was performed at presentation and during and after completion of chemotherapy and radiation therapy. Histopathologic studies were done at presentation, at 77 weeks (20 weeks after a pathological fracture), and from the en bloc resection at 104 weeks. Results. DEMRI predicted the early tumor response, absence of tumor recurrence, presence of necrosis and lack of fracture healing, confirmed by histopathology. Conclusion. DEMRI is a clinically useful tool in managing Ewing's sarcoma. (orig.)

1999-04-01

86

Evaluation of therapeutic results in Ewing's sarcoma  

International Nuclear Information System (INIS)

The philosophy pervading the treatment approach to Ewing's sarcoma was to have therapy encompass all foci of disease, including sites of occult or potential involvement in addition to obvious clinical manifestations. The experience with integrated methods of treatment in 66 consecutive patients at the National Cancer Institute is reviewed. A median survival of 18 months (44 percent 2 year survival rate) for patients with recognizable metastases on admission bears impressive witness to the value of adjuvant therapy in Ewing's sarcoma. Even more encouraging, an uncorrected 5 year survival rate of 53 percent (42 percent continuously free of disease) for patients given ''pyrophylactic'', adjuvant therapy indicates the potential for permanent control of disease in a significant fraction of cases with clinically localized primary tumors. (U.S.).

87

Transposons for cancer gene discovery: Sleeping Beauty and beyond  

UK PubMed Central (United Kingdom)

The use of Sleeping Beauty transposons as somatic mutagens to discover cancer genes in hematopoietic tumors and sarcomas has been documented. Here, we discuss the future of Sleeping...Full Text Available

2007-01-01

88

Targeting the p53 Pathway in Ewing Sarcoma  

UK PubMed Central (United Kingdom)

The p53 tumour suppressor plays a pivotal role in the prevention of oncogenic transformation. Cancers frequently evade the potent antitumour surveillance mechanisms of p53 through mutation of the TP53...Full Text Available

2011-01-01

89

Poikiloderma atrophicans vasculare as a pointer to reticulosis of the skin  

UK PubMed Central (United Kingdom)

A case of reticulosis of the skin (mycosis fungoides) terminating in reticulum cell sarcoma is described where the features of poikiloderma atrophicans vasculare had been present for 40 years. The...Full Text Available

1975-07-01

90

Molecular characterization of a unique retrovirus associated with a fish tumor.  

UK PubMed Central (United Kingdom)

The walleye dermal sarcoma is a mesenchymal tumor which seasonally affects up to 27% of adult walleye fish (Stizostedion vitreum). It arises multicentrically in the dermis, in which its development...Full Text Available

1992-01-01

91

Localizing potentially active post-transcriptional regulations in the Ewing's sarcoma gene regulatory network  

UK PubMed Central (United Kingdom)

BackgroundA wide range of techniques is now available for analyzing regulatory networks. Nonetheless, most of these techniques fail to interpret large-scale transcriptional data...Full Text Available

92

Effective radiation therapy on two cases of primary Ewing's sarcoma of the rib  

International Nuclear Information System (INIS)

Two cases of primary Ewing's sarcoma of the rib are reported, in which radiation therapy was quite effective. Case 1 was an 18-year-old female who had had an operation and radiation therapy for Ewing's sarcoma of the left 7th rib. She was referred to our hospital after a recurrent tumor was found. Radiation therapy (tumor dose 46.2 Gy) and chemotherapy were given. The tumor disappeared and there has been no relapse for 1 year and 3 months after the treatment. Case 2 was a 2-year-old-infant. Radiation therapy (tumor dose 74 Gy) was given for primary Ewing's sarcoma of the left 6th rib. The tumor became small and was successfully removed at operation. There has been no relapse or distant metastasis for 8 months following the operation. We emphasize the importance of multidisciplinary treatment in case 1 and the usefulness of preoperative radiotherapy in case 2. (author).

93

Autoantibodies to BRAF, a new family of autoantibodies associated with rheumatoid arthritis  

UK PubMed Central (United Kingdom)

IntroductionBRAF (v raf murine sarcoma viral oncogene homologue B1) is a serine-threonine kinase involved in the mitogen-activated protein kinase (MAPK) signalling pathway, known...Full Text Available

2010-01-01

94

Energy Management Action Network (EMAK). A scoping study investigating the establishment and support of an international and domestic action network of energy management in industry. Information paper  

Energy Technology Data Exchange (ETDEWEB)

The IEA has identified energy efficiency as essential to achieving a sustainable energy future. In order to improve energy efficiency in industry one of the priority areas for further action is the promotion of more and higher quality energy management (EM) activity. However, there are significant gaps in the current implementation of EM. One method of bridging these gaps would be the creation of an EM Action NetworK (EMAK) to bring practical support to energy managers, connect energy managers to energy policy makers, and interconnect these networks globally. The paper describes possible aims, activities, scope, structure, timelines and approaches related to EMAK and looks at specific tasks that would be important in the set-up and implementation.

2009-12-15

95

Assessment of cost savings of DOE's return-on-investment program  

Energy Technology Data Exchange (ETDEWEB)

The U.S. Department of Energy (DOE) Office of Pollution Prevention (EM-77) created is successful internally competed program to fund innovative projects based on projected returns. This is called the Return-on-Investment (ROI) program. EM-77 conducted a successful ROI pilot, developed and implemented sound management practices, and successfully transferred the program to several Operations Offices. Over the past 4 years sites have completed 262 ROI projects (costing $18.8 million) with claimed first-year savings of $88 million and claimed life cycle savings exceeding $300 million. EM-77 requested that Oak Ridge National Laboratory perform an independent evaluation of the site-led, DOE-HQ-funded pollution prevention (P2) ROI program to assist the Department in determining whether claimed savings are real.

1999-08-01

96

Radiotherapeutic methods for Ewing's sarcoma of the long tubular bones in children  

International Nuclear Information System (INIS)

Radiotherapeutic results of the Ewing sarcoma of the long tubular bones in 140 pediatric patients aged 3-16 are analyzed with the respect to different methods of irradiation. Three-field irradiation, the fields being located at 120 deg to one another with daily irradiation of all three fields at a focal dose of 2 Gy, was found superior in treatment of primary neoplasm. It is stressed that the disease termination mainly depends on the efficiency of primary neoplasm treatment, as the neoplasm reccurence generally is followed by metastases. Radiation load is calculated for maximal irradiation area of soft tissues in children.

97

Radiodiagnosis of Ewing's sarcoma of the rib in children  

International Nuclear Information System (INIS)

The results of the examination of 23 children with Ewing's sarcoma of the rib were analyzed: panoramic chest X-rays in 4 projections, spot radiographs of the robs, superexposed pictures, laterograms, urography, angiography, computerized tomography, and scanning of the skeleton. Causes of diagnostic errors made at the first consultation by a physician, were identified. Peculiarities of X-ray signs of tumors of this site in children were studied. Diagnostic difficulties in tumors complicated by pleurisy and in tumors of small sizes with extrapleural growth were shown. Inclusions in the extraoseous tumor component were noted in 8.7% of the cases.

98

Ewing's sarcoma: treatment and prognosis  

International Nuclear Information System (INIS)

The results of treatment of 134 cases of morphologically-verified localized Ewing's sarcoma were evaluated. A comparative analysis showed relapse-free survival to be significantly lower for radiation treatment (23 %) than for its combination with various cytostatic drugs. Two-year relapse-free survival rate was as high as 43 % in cases receiving sarcolysin or cyclophosphamide as adjuvants. This was matched by 47 % for adjuvant ardiamycin or carminomycin and 56 % for adriamycin plus cyclophosphamide and vincristine. Evaluation of long-term results of adjuvant chemotherapy showed sex, age and site involvement to be of certain prognostic value.

99

Ewing's sarcoma of the humerus mimicking fibrous dysplasia on imaging and biological behavior  

International Nuclear Information System (INIS)

We present the case of a 12-year-old girl who presented with a pathological fracture through a benign-appearing osteolytic lesion that was presumed to represent fibrous dysplasia. The fracture healed, and over the next 2.5 years there was further refracturing and healing with progressive osteolysis. A biopsy was performed and revealed Ewing's sarcoma. The disease was locally controlled by neoadjuvant chemotherapy and radiation therapy. The patient is disease free with excellent function 6 years following the discovery of the lesion. We illustrate and discuss the sequence of events. (orig.)

2005-05-01

100

Bone scanning in Ewing's sarcoma  

International Nuclear Information System (INIS)

This is a retrospective analysis of bone scans in 72 patients with Ewing's sarcoma. Sites of primary disease were found to be evenly distributed among the axial skeleton and the proximal and distal extremities. Primary disease sites in the axial skeleton were more frequently associated with metastases. Fifty-three of these patients had their first scans done at presentation; among them, 25 were found to have metastases. Unsuspected metastases were picked up in 28 of all the patients. Metastases at presentation were seen to be associated with a poorer prognosis.

101

In vitro radiation studies on Ewing's sarcoma cell lines and human bone marrow: application to the clinical use of total body irradiation (TBI)  

International Nuclear Information System (INIS)

Patients with Ewing's sarcoma who present with a central axis or proximal extremity primary and/or with metastatic disease have a poor prognosis despite aggressive combination chemotherapy and local irradiation. In this high risk group of patients, total body irradiation (TBI) has been proposed as a systemic adjuvant. To aid in the design of a clinical TBI protocol, the authors have studied in the in vitro radiation response of two established cell lines of Ewing's sarcoma and human bone marrow CFUc. The Ewing's lines showed a larger D_0 and anti-n compared to the bone marrow CFU. No repair of potentially lethal radiation damage (PLDR) was found after 4.5 Gy in plateau phase Ewing's sarcoma cells. A theoretical split dose survival curve for both the Ewing's sarcoma lines and human bone marrow CFUc using this TBI schedule shows a significantly lower surviving fraction (10"-"4-10"-"5) for the bone marrow ...

102

Structure functions of nuclei in fluctonic model with rescaling  

International Nuclear Information System (INIS)

It is shown that the available data on x, Q"2, and A dependence of nuclear structure functions and for their ratios (EMS effect) can be described in terms of the flucton model with rescaling of parton distributions in nuclei. The x, Q"2 and A dependence of nuclear structure functions in the cumulative range (x >1) is predicted.

104

Flucton model with scaling breaking: EMC effect and lepton pair production on nuclei  

International Nuclear Information System (INIS)

The EMS effect is explained in the flucton model as a consequence of scale invariance violation. Nontrivial behaviour of the ratio between structural functions and production cross sections for lepton pairs for different nuclei at x > 1 is predicted.

106

Ecotoxicology of Explosives  

Energy Technology Data Exchange (ETDEWEB)

Managing sites contaminated with munitions constituents is an international challenge. Although the choice of approach and the use of Ecological Risk Assessment (ERA) tools may vary from country to country, the assurance of quality and the direction of ecotoxicological research are universally recognized as shared concerns. Drawing on a multidisciplinary team of contributors, 'Ecotoxicology of Explosives' provides comprehensive and critical reviews available to date on fate, transport, and effects of explosives. The book delineates the state of the science of the ecotoxicology of explosives, past, present, and recently developed. It reviews the accessible fate and ecotoxicological data for energetic materials (EMs) and the methods for their development. The chapters characterize the fate of explosives in the environment, then provide information on their ecological effects in key environmental media, including aquatic, sedimentary, and terrestrial ...

2009-04-01

107

EM-MWD technology; EM-MWD system jitsuyoka gijutsu  

Energy Technology Data Exchange (ETDEWEB)

A project on the title is a special study of TRC (Technology Research Center) Japan National Oil Corporation, which aims at developing a system collecting many data near well bottom while drilling. The project is a 3-year project from 1993 to 1995 succeeding to results of a project on real-time drilling control technology which was finished in fiscal 1992. This paper is a record in fiscal 1993. In 1993, the first year, TRC starts a joint study with relational enterprises aiming at utilizing an EM-MWD (electromagnetic-measurement while drilling) system practically. Based on the past fruit of the study, the EM-MWD system was applied to an highly inclined well or a horizontal well. A total system was constructed, which improved electromagnetic radiation transmission efficiency, and reliability, and workability. An electromagnetic radiation receiver system for an offshore drilling rig was developed. A well bottom tools of 6-3/4 inches outer ...

1994-10-31

110

CRED Simrad em300 multibeam backscatter data from the submarine slope environment at Rose Island, American Samoa, South ...  

Science.gov (United States)

Multibeam backscatter imagery extracted from gridded bathymetry of Rose Island, American Samoa, South Pacific. These data provide coverage between 20 ... ...

112

State of work for services provided by the Waste Sampling and Characterization Facility for effluent monitoring  

International Nuclear Information System (INIS)

This document defines the services the Waste Sampling and Characterization Facility (WSCF) shall provide Effluent Monitoring (EM) throughout the calendar year for analysis. The internal memo contained in Appendix A identifies the samples Em plans to submit for analysis in CY-1995. Analysis of effluent (liquid and air discharges) and environmental (air, liquid, animal, and vegetative) samples is required using standard laboratory procedures, in accordance with regulatory and control requirements. This report describes regulatory reporting requirements and WSCF services and data quality objectives.

113

Hanford tanks initiative plan  

Energy Technology Data Exchange (ETDEWEB)

Abstract: The Hanford Tanks Initiative (HTI) is a five-year project resulting from the technical and financial partnership of the U.S. Department of Energy`s Office of Waste Management (EM-30) and Office of Science and Technology Development (EM-50). The HTI project accelerates activities to gain key technical, cost performance, and regulatory information on two high-level waste tanks. The HTI will provide a basis for design and regulatory decisions affecting the remainder of the Tank Waste Remediation System`s tank waste retrieval Program.

1997-07-01

114

Development of the SRS environmental counting laboratory gamma spectroscopy system  

International Nuclear Information System (INIS)

The Savannah River Site (SRS), one of several U.S. Department of Energy (DOE) facilities, produces nuclear materials for national defense and for other government and civilian uses. SRS ceased production of defense materials in 1988, and the site's main activities now involve waste management and environmental restoration. These programs have generated extensive effluent monitoring and environmental surveillance programs for the Environmental Monitoring Section (EMS), which performs #approx#105,000 radiological analyses on 30,000 samples a year. Gamma spectroscopy is performed on an estimated 10,000 samples annually. This report describes a program to develop and improve the EMS system.

1996-06-16

115

Ten-year cleanup of U.S. Department of Energy weapon sites: The changing roles for technology development in an era of privatization  

Energy Technology Data Exchange (ETDEWEB)

In its beginning, the U.S. Department of Energy (DOE) Office of Environmental Management (EM) viewed private industry as lacking adequate technology know-how to meet demands of hazardous and radioactive waste problems at the DOE`s laboratories and nuclear weapons production facilities. In November 1989, EM`s Office of Technology Development (recently renamed the Office of Science and Technology) embarked on a bold program of developing and demonstrating {open_quotes}innovative{close_quotes} waste cleanup technologies that would be safer, faster, more effective, and less expensive than the {open_quotes}baseline{close_quotes} commercial methods. This program has engaged DOE sites, national laboratories, and universities to produce preferred solutions to the problems of handling and treating DOE wastes. More recently, much of this work has shifted to joint efforts with private industry partners to accelerate the use of newly developed technologies ...

1996-12-31

116

Geophysical remote sensing of water reservoirs suitable for desalinization.  

Energy Technology Data Exchange (ETDEWEB)

In many parts of the United States, as well as other regions of the world, competing demands for fresh water or water suitable for desalination are outstripping sustainable supplies. In these areas, new water supplies are necessary to sustain economic development and agricultural uses, as well as support expanding populations, particularly in the Southwestern United States. Increasing the supply of water will more than likely come through desalinization of water reservoirs that are not suitable for present use. Surface-deployed seismic and electromagnetic (EM) methods have the potential for addressing these critical issues within large volumes of an aquifer at a lower cost than drilling and sampling. However, for detailed analysis of the water quality, some sampling utilizing boreholes would be required with geophysical methods being employed to extrapolate these sampled results to non-sampled regions of the aquifer. The research in this report addresses using ...

2009-12-01

117

Hyperfractionated radiotherapy with simultaneous chemotherapy in Ewing's sarcoma  

International Nuclear Information System (INIS)

In 1981, the German Society of Pediatric Oncology initiated a multi-institutional study for the treatment of Ewing's sarcoma. The protocol (Cooperative Ewing's Sarcoma Study, CESS 81) consisted of four courses of a four-drug-regimen (VACA), each course taking nine weeks. Local therapy (radical surgery or resection plus irradiation or radiotherapy alone) was performed after the second course. The results of CESS 81 can be summarized as follows: VACA-chemotherapy is effective in controlling systemic disease. Initial tumor mass and response to initial chemotherapy are of major prognostic value for local control and survival. Permanent local control is a problem, especially in irradiated patients. The high local failure rate in irradiated patients in CESS 81 could be attributable to the following reasons: Late start of local therapy (after 18 weeks of chemotherapy), uneven distribution of prognostic parameters: Large tumors were more often ...

118

Ewing's sarcoma: a combined approach in the management  

International Nuclear Information System (INIS)

Twenty-seven histologically confirmed cases of localised Ewing's sarcoma were treated by two different regimes. Radiotherapy alone was used in 13 cases and a combination of chemotherapy and radiotherapy in 14. Single agent chemotherapy (cyclophosphamide) was given sequentially in nine patients and cyclophosphamide and actinomycin-D in five. There is a significant difference in the response to these different regimes. Only 69.2% of patients treated by radiotherapy alone were disease-free, for a median period of 10.4 months and metastases were noticed in 53.8% of cases. The disease-free survival in patients treated by combination therapy (radiotherapy and chemotherapy) was 18.4 months and metastases were seen in only 42.9%. However, no metastases were seen in patients who received cyclophosphamide and actinomycin-D, during a period of 14 months and only one patient showed residual disease. It is concluded that the addition of cyclophosphamide alone is not adequate in ...

119

Diagnostic difficulties in extraosseous Ewing's sarcoma: A proposal for diagnostic criteria  

International Nuclear Information System (INIS)

Five cases diagnosed as extraosseous Ewing's sarcoma (EES) during a 15 year period, and the relevant literature, were reviewed. The diagnosis in these cases was difficult to confirm, mainly because the distinction between the osseous form of Ewing's sarcoma (OES) and either periosteal reactions or direct tumour invasion into adjacent bone by EES was often unclear. The literature suggests that other authors have also encountered difficulties. The authors believe that many cases reported as EES are likely to have been OES. This distinction has some importance, as the two conditions are usually treated in differing ways. The following criteria are proposed for the diagnosis of primary EES: (i) no evidence of bony involvement on magnetic resonance imaging; (ii) no evidence of increased uptake in bone or periosteum adjacent to the tumour on static isotope bone scan images; (iii) a small round cell tumour with no differentiating features on light ...

120

Combined chemotherapy and radiotherapy of localized and metastasizing Ewing's sarcoma  

International Nuclear Information System (INIS)

Between 1973 and 1978 combined radiotherapy and chemotherapy were given to 22 patients with histologically proven Ewing's sarcoma. The combined chemotherapy consisted of cyclophosphamide, vincristin, adriamycin, as well as dacarbazine in some cases. The neoplasm was a localized one at the beginning of treatment in 14 of the 22. These patients received high-voltage rediotherapy to the primary focus at a focal dose between 42 and 55 Gray (4200-5500 rad), followed by chemotherapy. After 6-8 treatment cycles, adriamycin was replaced by methotrexate. Nine of the 14 patients survived without recurrence for 12 to over 59 months. Eight patients had extensive metastases at the beginning of treatment: they at first received only chemotherapy, followed by radiotherapy or operation, as indicated. Full clinical remission was achieved in five of them: in three this remission has now lasted for more than 18, 40 and 44 months, respectively. These results indicate that (1) ...

121

Risk of radiation-related subsequent malignant tumors in survivors of Ewing's sarcoma  

International Nuclear Information System (INIS)

Twenty-four long-term survivors of Ewing's sarcoma were identified as being at risk for a second primary tumor. Among this group of patients followed from 3 to 22 y, 4 new bone tumors were observed, whereas 1.2 x 10"-"3 were expected. All new tumors arose in heavily irradiated areas. The risk associated with radiation after 3 years was 7.2 cases/million person-years per rad. The cumulative cancer risk over 10 years for irradiated patients was 35% (SE, 15.1%). Intensive chemotherapy (cyclophosphamide and vincristine administered in five or more courses) seemed to exert an enhancing effect, increasing the rate of development of new tumors.

122

Quantitative bone scintigraphy: follow-up of a femoral osteogenic sarcoma in an adolescent girl treated by chemotherapy and by massive allograft  

International Nuclear Information System (INIS)

Fifteen quantitative bone scintigraphies were performed in an adolescent girl during the follow-up of a femoral osteogenic sarcoma treated by chemotherapy and massive allograft. Three hours after injection of the radiopharmaceutical (7.4 MBq/kg of 99mTc-MDP) bone activity was measured in the inferior limbs at several regions of interest centered on the hips, femurs (proximal, middle, distal) and proximal tibias. The variations of relative bone activities A/S (ratio of corresponding counting rates between two homologous regions in the affected A and in the healthy S limb) and of absolute bone activities (expressed in counts/pixel-second) are interpreted as a function of times during treatment. The quantitative results are discussed with regard to main phenomena influencing bone activity in this particular clinical case: bone growth, chemotherapy and neo-osteogenesis in allograft.

123

Primary cutaneous Ewing's sarcoma/primitive neuroectodermal tumor manifesting numerous small and huge ulcerated masses: its complete remission by chemotherapy and magnetic resonance imaging findings  

International Nuclear Information System (INIS)

Extraskeletal Ewing's sarcoma (ES) and primitive neuroectodermal tumor (PNET) are widely regarded as clinically and histologically identical tumors which consist of small blue round cells. Extraskeletal ESs/PNETs usually occur in the deep soft tissues of the paraspinal region, chest wall, or lower extremities. However, superficially located cases, so-called cutaneous ESs/PNETs, are exceedingly rare, and the vast majority of the reported cases present as a single small mass. We present magnetic resonance imaging (MRI) findings and clinical course of a unique case of primary cutaneous ES/PNET presenting as numerous huge masses with severe ulceration on them. (orig.)

2010-06-01

124

Local control of Ewing's sarcoma: an analysis of 67 patients  

International Nuclear Information System (INIS)

Local control of Ewing's sarcoma was analysed in a series of 67 patients treated by surgery and/or radiotherapy as well as combination chemotherapy. Radiotherapy was employed with or without surgery in 60 patients and produced an overall local control rate of 55%; complete excision of the primary lesion seemed to be beneficial. There was a marked variation in control rates depending on the site of the primary lesion: limb 85%, rib 53%, pelvis 31% and other sites 33%.Primary tumours greater than 10 cm in diameter were significantly less likely to be controlled. Using daily fractions of approximately 180 cGy, total doses in excess of 6000 cGy seem more likely to produce serious late morbidity amd may not increase the local control rate. No cases of second malignancy arising in irradiated tissue have been observed to date, but one patient developed acute lymphoblastic leukaemia. (author).

125

Local control of Ewing's sarcoma of bone with radiotherapy and combination chemotherapy  

International Nuclear Information System (INIS)

Between 1964 and 1977, 94 patients with Ewing's sarcoma of bone were treated at the National Cancer Institute. They received 5000 rad to the whole bone and progressively more aggressive chemotherapy protocols. The patients were divided according to site of primary lesion into central, proximal and distal lesions, with 19%, 33% and 57%, respectively, alive and well. The local control rate is high (93%), with good functional results in the distal lesions, and no changes are needed in radiation therapy dose or volume. Control is not as satisfactory for central and proximal lesions and efforts need to be made to increase control at these sites. We are at present attempting to define more accurately the extent of soft tissue disease, increasing the dose to 6000 rad for central lesions, and using a more aggressive chemotherapy program, in the hope of increasing the local control in these more aggressive tumors.

126

Ewing's sarcoma of the vertebral column  

International Nuclear Information System (INIS)

Twenty-two patients with vertebral primaries were registered in the Intergroup Ewing's Sarcoma Study between 1973 and 1977. The radiation doses to the primary tumors ranged between 3800 and 6200 rad. All patients received intensive combination chemotherapy. After a followup ranging between 14 and 62 months, 14 patients remained disease-free. All patients with primary tumor of the cervical and dorsal spine remained disease-free. Of eight patients with lesions in the distal spine, (sacrococcygeal region) six developed recurrence, in three a local recurrence was observed despite doses of 6000 rad or higher. Doses of 5000 rad or less (in addition to combination chemotherapy as used in the Intergroup Ewing's Study) appear adequate in controlling the primary tumors of the proximal segments of the spinal column.

127

Ewing's Sarcoma : a study of 38 cases  

International Nuclear Information System (INIS)

A retrospective study of Ewing's Sarcoma at The Armed Forces Malignant Diseases Treatment Centre, Command Hospital, Pune, is presented. A total of 38 cases over a period of thirteen years have been studied. Males predominate slightly, and the common age group on presentation has been in the second and third decade. Humerus, pelvis and femur are the bones commonly affected. The initial line of management has been primarily radiotherapy, which has been over the years supplemented by combination chemotherapy. All the cases achieved remission, though only 32 cases (84 per cent) had complete remission, and the remaining only partial remission. The overall survival in those offered aggressive therapy has been over 50 per cent in two years. The present policy in the management of these cases is discussed. (author). 4 tabs.

128

X-ray, Optical, and Radio Observations of SN 1999em and SN 1998S  

CERN Document Server

Observations of the Type II-P (plateau) Supernova (SN) 1999em and Type IIn (narrow emission line) SN 1998S have enabled estimation of the profile of the SN ejecta, the structure of the circumstellar medium (CSM) established by the pre-SN stellar wind, and the nature of the shock interaction. SN 1999em is the first and only Type II-P detected at both X-ray and radio wavelengths. It is the least radio luminous and one of the least X-ray luminous SN ever detected (except for the unusual and very close SN 1987A). The Chandra X-ray data indicate non-radiative interaction of SN ejecta with a power-law density profile (rho \\propto r^{-n} with n ~ 7) with a pre-SN wind with a low mass loss rate of ~2 \\times 10^{-6} Msun/yr for a wind velocity of 10 km/sec, in close agreement with radio mass-loss rate estimates. The Chandra data show an unexpected, temporary rise in the 0.4--2.0 keV X-ray flux at ~100 days after explosion. SN 1998S appears reasonably ...

2001-01-01

129

The Quantum Vacuum of Complex Media. A Unified Approach to the Dielectric Constant, the Spontaneous Emission and the Zero-Temperature Electromagnetic Pressure  

CERN Document Server

We study from a critical perspective several quantum-electrodynamic phenomena commonly related to vacuum electromagnetic (EM) fluctuations in complex media. We compute the resonance-shift, the spontaneous emission rate, the local density of states and the van-der-Waals-Casimir pressure in a dielectric medium using a microscopic diagrammatic approach. We find, in agreement with some recent works, that these effects cannot be attributed to variations on the energy of the EM vacuum but to variations of the dielectric self-energy. This energy is the result of the interaction of the bare polarizability of the dielectric constituents with the EM fluctuations of an actually polarized vacuum. We have found an exact expression for the spectrum of these fluctuations in a statistically homogeneous dielectric. Those fluctuations turn out to be different to the ones of normal radiative modes. It is the latter that carry the ...

2009-01-01

130

In Situ Remediation Integrated Program: FY 1994 program summary  

Energy Technology Data Exchange (ETDEWEB)

The US Department of Energy (DOE) established the Office of Technology Development (EM-50) as an element of the Office of Environmental Management (EM) in November 1989. In an effort to focus resources and address priority needs, EM-50 introduced the concept of integrated programs (IPs) and integrated demonstrations (IDs). The In Situ Remediation Integrated Program (ISR IP) focuses research and development on the in-place treatment of contaminated environmental media, such as soil and groundwater, and the containment of contaminants to prevent the contaminants from spreading through the environment. Using in situ remediation technologies to clean up DOE sites minimizes adverse health effects on workers and the public by reducing contact exposure. The technologies also reduce cleanup costs by orders of magnitude. This report summarizes project work conducted in FY 1994 under the ISR IP in three major areas: treatment ...

1995-04-01

131

From waste minimization to ISO 14000: Taiwan`s experience and prospects  

Energy Technology Data Exchange (ETDEWEB)

Taiwan has completed a very successful five-year industrial waste minimization (IWM) demonstration and promotion project sponsored by the government. From 1990 to 1995, the project successfully disseminated the IWM concept of pollution prevention (P2) to industries. It effectively reduced industrial waste while significantly benefitting the economy by assisting industries in implementing in-plant IWM programs. In July 1995, the second stage of the five-year IWM and ISO 14000 promotion project was initiated for further promoting the IWM, P2, and cleaner production and, in particular, coping with the upcoming international environmental management standards (ISO 14000). To assist industries in establishing an environmental management system (EMS) and accumulating related experience, an EMS pilot demonstration project of five model industries and an ISO 14001 EMS demonstration and promotion project for 22 factories in 13 ...

1996-12-31

132

UNITED STATES DEPARTMENT OF ENERGY WASTE PROCESSING ANNUAL TECHNOLOGY DEVELOPMENT REPORT 2007  

Energy Technology Data Exchange (ETDEWEB)

The Office of Environmental Management's (EM) Roadmap, U.S. Department of Energy--Office of Environmental Management Engineering & Technology Roadmap (Roadmap), defines the Department's intent to reduce the technical risk and uncertainty in its cleanup programs. The unique nature of many of the remaining facilities will require a strong and responsive engineering and technology program to improve worker and public safety, and reduce costs and environmental impacts while completing the cleanup program. The technical risks and uncertainties associated with cleanup program were identified through: (1) project risk assessments, (2) programmatic external technical reviews and technology readiness assessments, and (3) direct site input. In order to address these needs, the technical risks and uncertainties were compiled and divided into the program areas of: Waste Processing, Groundwater and Soil Remediation, and Deactivation and Decommissioning ...

2008-08-12

133

Use of surface affinity enrichment and cryo-embedding to prepare in vitro reconstituted mitotic chromosomes for EM tomography  

Energy Technology Data Exchange (ETDEWEB)

We present a novel preparation method for studies of in vitro reconstituted mitotic chromosomes from Xenopus laevis egg extracts. This method involves a gentle adsorption of chromosomes from the extracts using surface affinity enrichment, followed by plunge freezing, freeze-substitution and cryo-embedding before examination by EM tomography. For comparison, chromosomes were also prepared by a conventional method, which included immobilization of chromosomes in agarose and a room-temperature dehydration (embedding) protocol. Three-dimensional reconstructions showed that samples prepared with the new method have a greater interconnectivity of sub-structural features and a higher compaction ratio together with an apparently less perturbed chromatin structure than those prepared using the conventional approach. The implications of the new method for the preparation of other difficult samples and additional application possibilities are discussed.

2005-07-15

134

The Bedwyr system for model checking over syntactic expressions  

CERN Document Server

Bedwyr is a generalization of logic programming that allows model checking directly on syntactic expressions possibly containing bindings. This system, written in OCaml, is a direct implementation of two recent advances in the theory of proof search. The first is centered on the fact that both finite success and finite failure can be captured in the sequent calculus by incorporating inference rules for {\\em definitions} that allow {\\em fixed points} to be explored. As a result, proof search in such a sequent calculus can capture simple model checking problems as well as may and must behavior in operational semantics. The second is that higher-order abstract syntax is directly supported using term-level $\\lambda$-binders and the quantifier known as $\

2007-01-01

135

Surface equation of state for pulmonary surfactant monolayers at Air-Water interface: Protein-lipid binary mixture monolayers  

British Library Electronic Table of Contents (United Kingdom)

Abstract The available surface equation of state for pure pulmonary surfactant monolayers is generalised to binary mixture monolayers by introducing a group of parameters, i(i-=-1-4) in the form of $x_{r}^{\\beta _{i} } $ to express the influence of the components in new mixing rules and a new factor, I $\\left[ { = \\left( {\\prod\\limits_{i = 1}^{4} {\\beta _{i} } } \\right)^{{\\raise0.5ex\\hbox{$\\scriptstyle 1$}\\kern-0.1em/\\kern-0.15em\\lower0.25ex\\hbox{$\\scriptstyle {4}$}}} } \\right]$, is defined to represent the interaction intensity between two different components. The ---A isotherms getting by the surface equations of state agree with the experimental data for protein-lipid binary monolayers, and the average deviation is about 11.41%. The result shows the order of the interaction intensity b...

2010-01-01

136

On external network model development  

Energy Technology Data Exchange (ETDEWEB)

Although state estimation is a mature technique which is widely available in the EMS industry, experience with practical implementation and use of state estimation and network security analysis functions at electric power utilities over the last two decades indicates recurring difficulties and problems attributable to inadequate external network modeling detail and data. This paper addresses the development of a set of guidelines for external network modeling and data exchange, based on the results of a recent project sponsored by EPRI. A general methodology is developed based on the results of a survey of a representative set of utilities and EMS suppliers, supplemented by subsequent analysis and simulation studies. Distinction is made between guidelines pertaining to external network topology, analog measurements, data exchange, and implementation procedures. A philosophy and approach for constructing and testing external models is also ...

1996-05-01

137

Deep inelastic scattering of leptons on nuclei  

International Nuclear Information System (INIS)

Experimental studied of deep-inelastic scattering of neutrino, antineutrino, #mu#-mesons, electron reactions on He, D, Al, Fe, Au, Be, C, Ca, Ag, N nuclei conducted in recent years at different laboratories the world for consideration of modern status of the problems of R(x, Q"2) = #sigma#sub(L)/#sigma#sub(T) parameter variation and for study on nuclear effects in structural functions of nucleons are described in the review. Experimental information on measurements of the R parameter by data on EMS and SLAK groups is analyzed. It is noted that experimental data on measuring R contain essential errors that hampers unambiguous interpretation of data on nucleon structure. Present experimental data and predictions for explanation of the EMS effect are analyzed from the view point of quark and flucton models of a nucleus.

1984-06-19

138

A case-based approach to outpatient evaluation and management service coding.  

Science.gov (United States)

Understanding Center for Medicare and Medicaid Services (CMS) documentation and coding rules is challenging for most physicians. To accurately bill for clinical services, physicians must learn a system that may initially seem daunting, but is in fact governed by a small number of straightforward rules. The Evaluation and Management (E/M) guidelines for all service codes specify 3 components: history, examination, and medical decision-making, each with a defined set of elements or characteristics. Service coding is based on the level of care supported by the number of history and examination elements and the complexity of decision-making. This article will clarify the guidelines for outpatient clinical services and suggest a practical method of selecting appropriate E/M codes. Because physicians must often choose between billing codes 99213 and 99214 for a visit by an established patient, it will particularly focus on the minimum documentation ...

2008-11-01

139

Role of radiation therapy in the management of nonmetastatic Ewing's sarcoma of bone. Report of the intergroup Ewing's sarcoma study  

International Nuclear Information System (INIS)

The role of radiation therapy in local tumor control and decreased incidence of pulmonary metastasis is reported in 271 patients who were entered into the Intergroup Ewing's Sarcoma Study with more than one year follow-up and on whom all radiotherapy records were reviewed. The majority of the patients were irradiated to the primary tumor with doses of 4500 to 6500 rad in five to six weeks in combination with systemic administration of three drugs (vincristine, actinomycin-D and cyclophosphamide) or four drugs (vincristine, actinomycin-D, cyclophosphamide and adriamycin). One of the groups of patients was treated with three drugs and bilateral pulmonary irradiation (1500 rad, uncorrected dose, in two weeks). Preliminary analysis shows an overall local primary tumor control of 89%. Patients with lesions in the pelvis had a local failure rate of 17% (9 of 52) and in the humerus 23% (7 of 31). Factors affecting local recurrences are analyzed in detail. Distant ...

140

Radiologic findings of extraosseous Ewing's sarcoma  

International Nuclear Information System (INIS)

The purpose of this study is to evaluate the radiologic findings of the extraosseous Ewing's sarcoma. Six patients with pathologically confirmed extraosseous Ewing's sarcoma were retrospectively reviewed. Patients included two men and four women with an average age of 21.5 years (age range 9-48 years). Plain radiographs (six patients), magnetic resonance (MR) images (five patients), computed tomographic (CT) scans (three patients) and whole body scintigraphy (two patients) were reviewed and analyzed. Images were evaluated with regard to lesion location, size, margin, muscle or bone involvement and intrinsic imaging characteristics on CT and MRI. The tumors were located in the thigh (three patients), back (two patients) and upper arm (one patient). The tumors ranged in size from 2.3 cm to 7.5 cm (mean, 5.2 cm), were mainly well circumscribed and showed no evidence of calcification prior to treatment. Margins were well defined in four out of the ...

2005-09-01

141

Radiation therapy in the multimodal management of Ewing's sarcoma of bone: report of the Intergroup Ewing's Sarcoma Study  

International Nuclear Information System (INIS)

This paper is a progress report on the role of radiation therapy (RT) in local tumor control and the decreased incidence of pulmonary metastasis in 251 patients entered in the Intergroup Ewing's Sarcoma Study. All were followed for more that 1 year, and their RT records were reviewed. Doses to the primary tumor in the range of 4,500--6,500 rad were administered over approximately 5 to 6 weeks in combination with 4 drugs, i.e., vincristine (VCR), dactinomycin (DAC), cyclophosphamide (CY), and adriamycin, or only the first 3. One group of patients received the 3 drugs and bilateral pulmonary irradiation (approximately 1,500 rad in 2 wk). Preliminary analysis showed a local primary tumor control of approximately 90%. Patients with lesions in the pelvis and humerus had local failure rates of 13% (7 of 54) and 21.4% (6 of 28), respectively. The treatment groups differed significantly in the incidence of pulmonary metastasis. Patients treated with the 4 drugs (regimen 1) ...

142

Primary spinal epidural extraosseous Ewing's sarcoma: Report of five cases and literature review  

International Nuclear Information System (INIS)

Ewing's sarcoma is the most common malignant bone tumour occurring in children and adolescents and exists in two different clinico pathological entities: osseous Ewing's sarcoma (OES) and extraosseous Ewing's sarcoma (EES). Five cases of primary epidural EES are described, which presented with non-specific symptoms leading to a long diagnostic delay. The median age at diagnosis was 22 years (range 13-36 years). The median diagnostic delay was 3 months. All patients had one or more neurological deficits. All underwent surgical exploration with a laminectomy and partial resection followed by adjuvant radiotherapy to a dose of 46-50 Gy and chemotherapy with VAC (vincristine, adriamycin and cyclophosphamide) alternating with ICE (ifosphamide, cisplatin and etoposide) for at least six cycles. The mean follow-up period is 21.2 months (range 11-32 months). Four of the five patients achieved a complete remission and are disease ...

2001-08-01

143

Long-term results following multidisciplinary treatment of localized Ewing's sarcoma in children and adolescents  

International Nuclear Information System (INIS)

Purpose: To identify results and prognostic factors on long-term survival and local control following treatment of localized Ewing's sarcoma. Patients and Methods: Between 1979 and 2004, a total of 60 children and young adults with Ewing's sarcoma were treated. Patients with distant metastases at presentation (n = 6) and recurrent cases (n = 2) were excluded from this analysis. Patients were exclusively treated within ongoing national and international protocols CESS-81, CESS-86, EICESS-92, EURO-EWING-99. All patients received local irradiation with a total dose of 45-60 Gy; in addition, 41 (79%) of the patients had local surgical procedures, 27 (52%) of them with clear margins. Results: Overall survival rates at 5 and 10 years were 56% and 45%, respectively. Patients #<=# 14 years at diagnosis had overall survival rates of 66% and 61% at 5 and 10 years compared to older patients with corresponding survival rates of 47% and 31%, respectively ...

2008-03-01

144

Localization of an anti-tumour monoclonal antibody in human tumour xenografts: kinetic and quantitative studies with the 791T/36 antibody  

International Nuclear Information System (INIS)

Studies have been performed with an anti-osteogenic sarcoma monoclonal antibody 791T/36 and human tumour xenografts to examine some of the quantitative and kinetic aspects of tumour localization. The influence of variations in tumour size and site and antibody dose on the extent and rate of specific antibody localization have been examined, together with the site of intratumoural deposition of the antibody. (UK).

145

Instrument of millimetre wave radiation and its effect on malignant tumor in mice and its application in clinic  

Energy Technology Data Exchange (ETDEWEB)

An animated test is made for mice with malignant tumors irradiated by a self-made millimetre wave radiator for medical purpose. It is observed that S-180 sarcomas in mice after irradiation has been distinctly suppressed. And remarkable effects are shown through a lot of clinical practices on peptic ulcer, skin-deep ulcer, acute and chromic soft tissue injuries etc.

1995-12-31

146

Ewing's sarcoma treatment in Scandinavia 1984-1990. Ten-year results of the Scandinavian sarcoma group protocol SSGIV  

International Nuclear Information System (INIS)

A report on the long-term follow up of the first cooperative Scandinavian Sarcoma Group study in Ewing's sarcoma of bone is presented. Fifty-two previously untreated patients entered the study between 1984 and 1990. Half of the tumors were located in the extremities and one quarter in the pelvis. The combined modality treatment consisted of 5 cycles of chemotherapy - including vincristine, methotrexate, doxorubicin, cyclophosphamide, bleomycin and dactinomycin. The first two cycles were followed by local resection or amputation in 35 patients and by radiotherapy alone in 17 patients. When surgery was not performed, was incomplete or yielded poor margins radiotherapy was given at a dose of 40-60 Gy. Local tumor relapses developed in 10 patients and in all but one patient were accompanied by metastatic disease. Five patients had metastasis at diagnosis and distant metastases developed after primary treatment in 27 patients after a median of 14 ...

147

Diagnosis and treatment of Ewing's sarcoma  

International Nuclear Information System (INIS)

Ewing's sarcoma is a small round-cell tumor typically arising in the bones, rarely in soft tissues, of children and adolescents. Ewing's sarcoma has retained the most unfavorable prognosis of all primary musculoskeletal tumors. Prior to the use of multi-drug chemotherapy, long-term survival was less than 10%. The development of multi-disciplinary therapy with chemotherapy, irradiation, and surgery has increased current long-term survival rates in most clinical centers to greater than 50%. In addition, the preferred method of tumor resection has changed; limb salvage has nearly replaced amputation of the affected limb. Limb salvage procedures can be performed in place of amputation without compromising patient survival rates. Recent studies have revealed that the pathognomonic translocations involving the EWS gene on chromosome 22 and an ETS-type gene, which is most commonly the Fli1 gene on chromosome 11, are implicated in more than 95% of ...

2007-02-01

148

Case of an unusual clinical and radiological presentation of pulmonary metastasis from a costal chondrosarcoma after wide surgical resection: A transbronchial biopsy is recommended  

UK PubMed Central (United Kingdom)

Chondrosarcomas are the most frequently occurring primary malignant chest wall tumors. Furthermore, the lungs serve as the most frequent sites for metastases. Pulmonary metastases from sarcomas usually...Full Text Available

149

The oxygenation of [3-methyl-3H]desacetoxycephalosporin C [7beta-(5-D-aminadipamido)-3-methylceph-3-em-4-carboxylic acid] to [3-hydroxymethyl-3H]desacetylcephalosporin C by 2-oxoglutarate-linked dioxygenases from Acremonium chrysogenum and Streptomyces clavuligerus.  

UK PubMed Central (United Kingdom)

Cell-free extracts of Acremonium chrysogenum and Streptomyces clavuligerus oxidize the 3-methyl group of desacetoxycephalosporin C to a 3-hydroxymethyl group. The enzyme responsible for this reaction...Full Text Available

1978-09-01

151

Production of three vector bosons in {gamma} {gamma} colliders; Producao de tres bosons vetoriais em {gamma} {gamma} colliders  

Energy Technology Data Exchange (ETDEWEB)

The production of three vector bosons in {gamma} {gamma} collisions studying the reactions {gamma} + {gamma} {yields} W{sup +} + W{sup -} + Z{sup 0} and {gamma} + {gamma} {yields} W{sup +} + W{sup -} + {gamma}. 12 refs., 4 figs., 2 tabs.

1994-12-31

152

Modalidade de morte em mamiferos expostos a irradiacao de corpo inteiro (sindrome aguda da radiacao). (Modes of death in mammals exposed to whole body radiation (acute radiation syndromes)).  

Science.gov (United States)

When an animal is exposed to a sufficient amount of radiation, there will be changes in many organs of the body, and as a result of either the effects in one particular organ or the interaction of effects in several organs, the animal as a whole will show...

1990-01-01

153

Electric loading of power transmission lines - statistical methodology and real time management; Carregamento eletrico de linhas de transmissao - metodologia estatistica e gerenciamento em tempo real  

Energy Technology Data Exchange (ETDEWEB)

This paper shows a computerized system, that adopt a statistical methodology and simultaneous measurements of wind velocity and environment temperature, as an experiences at the power transmission lines with environmental monitoring systems. 9 figs., 16 refs.

1991-12-31

154

Cumulative hadron production in quark models of flucton fragmentation  

International Nuclear Information System (INIS)

Quark models of cumulative particle production and EMS effect are analyzed. All the models are characterized by a universal relationship between the spectrum of cumulative nucleons and the cross section of cumulative particles containing valence nuclear quarks. This relationship is tested for a deuteron. The role is discussed played by secondary nuclear processes for heavy nuclei. A special role of ''sea'' cumulative particles (K"-, p-bar) is pointed out in understanding the nature of the difference between the structure functions of a nucleus and of free nucleon.

155

Corona effect in high voltage transmission lines; O efeito corona em linhas eletricas aereas de alta-tensao  

Energy Technology Data Exchange (ETDEWEB)

Corona from bare conductors of electrical overhead power lines is studied in this article. Its origin, as well as, its bad influences over communication systems are both studied, yet. Line`s models are defined, in order to be able the examination of Corona on line`s cables. Formulas for the surface electrical gradient calculations are shown. (author) 2 refs.

1993-12-01

156

Prevention of central nervous system involvement with intrathecal _1_9_8Au colloid and methotrexate in non-Hodgkin lymphoma, acute non-lymphatic leukaemia and Ewing's sarcoma  

International Nuclear Information System (INIS)

Intrathecal _1_9_8Au colloid and methotrexate were administered to 27 children (between 1972 and 1981) with non-lymphatic leukaemia, 21 with non-Hodgkin lymphoma and two with Ewing's sarcoma to prevent CNS involvement. In one boy with non-lymphatic leukaemia a stable remission after a three-year period of cytostatic treatment ended with isolated CNS involvement. No isolated CNS recurrence occurred in children with non-Hodgkin lymphoma receiving regular radiogold administration. Combined iris and CNS recurrence occurred in one child with non-Hodkin lymphoma. Eleven of 21 children with non-Hodgkin lymphoma have been in complete initial remission for 4-39 months without cytostatic treatment. Late cerebral complications have not been observed after _1_9_8Au colloid and methotrexate. (orig.).

157

Multistep process of neoplastic transformation of normal human fibroblasts by 60Co gamma rays and Harvey sarcoma viruses  

Energy Technology Data Exchange (ETDEWEB)

As reported previously (Namba et al., 1985), normal human fibroblasts were transformed by 60Co gamma-ray irradiation into immortal cells with abnormal karyotypes. These transformed cells (KMST-6), however, showed a low cloning efficiency in soft agar and no transplantability. However, upon treatment with Harvey murine sarcoma virus (Ha-MSV), the cells acquired elevated clonability in soft agar and transplantability in nude mice. Ha-MSV alone, however, did not convert normal human fibroblasts into either immortal or tumorigenic cells. The Ha-MSV-transformed KMST-6 cells showed an enhanced expression of the ras oncogene, but normal and 60Co gamma-ray-transformed cells did not. Our current data suggest that gamma rays worked against normal human cells as an initiator, giving rise to chromosome aberrations and immortality, and that Ha-MSV, probably through its ras oncogene, played a role in the progression of the malignant cell population to a more malignant one ...

1986-03-15

158

Management of Ewing's sarcoma  

International Nuclear Information System (INIS)

Forty cases of Ewing's sarcoma of various sites had attended the Department of Radiotherapy at the Wanless Hospital and the Miraj Medical Centre, attached to the Government Medical College, Miraj, Maharashtra, from January, 1970 through December, 1979. There were 28 male patients and 12 female patients in the series with a male to female ratio of 2.3:1. The youngest patient in the series was a female of 6 years of age with the tumour in the scapula and the oldest patient was a 32-year-old male with a lesion in the metacarpal bone. Sixty per cent of the cases were seen in the second decade. The average age of the patients was 13.5 years. The bones of the lower extremities were most commonly involved with the highest number (35 per cent) of the cases occurring in the femur. Involvement of the bones of the right side of the body was almost equal to that of the left side. Swelling over the site of the lesion and pain over the swelling were the most common complaints ...

159

Local control and survival of Ewing's sarcoma in children with radiotherapy and chemotherapy without radical surgery  

International Nuclear Information System (INIS)

The present study was undertaken in 27 children with localized Ewing's sarcoma treated at our hospital. In 9 cases the lesion was central and in 18 peripheral. Treatment consisted of: 1) Chemotherapy with 6 drugs (vincristine, cyclophosphamide, methotrexate, bleomycin, dactinomycin and doxorubicin) for one year in all patients; 2) Radiotherapy in 24 patients at a dose of 30-40 Gy in the entire bone with a booster dose of 10-15 Gy in the lesion. In 7 patients debulking surgery was performed followed by irradiation. Two cases with tumor in expendable bones and one with extensive destructive lesion in the tibia underwent radical surgery. One patient suffered local recurrence (femur) and 6 developed distant metastases. The remaining 20 (74%) patients were alive and tumor-free after follow-up periods of 17-80 months. Among the 12 patients with extremity lesions who were alive, 7 (58%) had minimal or mild treatment sequelae, 2 moderate, and 3 severe sequelae but no ...

160

Local control and sequelae following irradiation of Ewing's sarcoma  

International Nuclear Information System (INIS)

135 patients with histologically proven Ewing's sarcoma, treated at the Institute Gustave Roussy between 1960-1974 were reviewed in order to establish the effectiveness and the complications associated with radiotherapy. In 133 patients, a dose of at least 60 Gy for long bones, 55 Gy for flat bones and 45 Gy for vertebrae was given. 26 major complications (of which more than one occured in certain patients) were observed: 12 cases of growth retardation, loss of joint function in 7 cases, 3 fractures, 2 osteonecroses, 2 cases of delayed healing, one massive soft tissue fibrosis, 1 abdominocutaneous fistula, 2 cases of symptomatic pulmonary fibrosis with associated infection, 2 cases of radiation enteropathy, 2 of mammary hypoplasia and 1 osteosarcoma developing in an irradiated zone. These complications necessitated 12 surgical interventions, including 4 disarticulations or amputations. The incidence of complications can be related to the age of the patient and to ...

161

GROWTH REGULATION IN ROUS SARCOMA VIRUS INFECTED CHICKEN EMBRYO FIBROBLASTS: THE ROLE OF THE src GENE  

Energy Technology Data Exchange (ETDEWEB)

We report here a study of the mechanisms leading to loss of growth control in chicken embryo fibroblasts transformed by Rous sarcoma virus (RSV). We have been particularly concerned with the role of the src gene in this process, and have used RSV mutants temperature sensitive (ts) for transformation to investigate the nature of the growth regulatory lesion. The two principal findings were (1) the stationary phase of the cell cycle (G{sub 1}) in chick embryo fibroblasts seems to have two distinct regulatory compartments (using the terminology of Brooks et al. we refer to these as 'Q' and 'A' states). When rendered stationary at 41.5 C by serum deprivation, normal cells enter a Q state, but cells infected with the ts-mutant occupy an A state. (2) Whereas normal cells can occupy either state depending on culture conditions, the ts-infected cells, at 41.5 C, do not seem to enter Q even though a known src gene product, a kinase, is ...

1980-07-01

162

Ewing's sarcoma. Radiographic pattern of healing and bony complications in patients with long-term survival  

International Nuclear Information System (INIS)

The radiographic appearance of Ewing's sarcoma was studied retrospectively in 22 patients who survived 5 years or longer after diagnosis and treatment. Expected changes from treatment, including regression of the extraosseous soft tissue mass, periostitis, and reconstitution of the cortex, occurred in all patients. Local recurrence occurred in one patient 10 years after complete remission whereas secondary osteosarcoma occurred more than 5 years after complete remission in two other cases. Both recurrent and secondary tumors presented as new lytic foci at the site of the original primary lesion. Lytic changes from radiation (radiation osteitis) may develop more than 2 years after treatment and in this sample; such findings were widely distributed in the radiation port. The authors conclude that bone remodeling and postradiation changes occur slowly over 2 years after treatment, and that any localized lysis at the primary site is suspicious for recurrence or ...

163

Ewing's sarcoma. Evaluation of radiotherapy and control of the primary tumor  

International Nuclear Information System (INIS)

From 1964 to 1973 at the Institute of Oncology and Radiobiology, Havana City, 18 clinical histories were studied, all of them from patients with Erwing's sarcoma, histologically diagnosticated by biopsy. Age, sex, race, traumatism background, hemogram disturbances, radiographic signs, primary tumor localization, and early treatment, were exposed. Early treatment in 14(83%) patients as radiotherapy. Local recurrence or metastasis was presented in 10(55,5%) patients during the two first years following attack treatment. Five (35,7%) patients was the survival rate within five years starting early treatemt. After five years, three (21,4%) patients were alive: for 18 and 14 year, and 64 month period; two patients died at 62 and 64 months. It is concluded that this survival may be increased by initial behaviour enclosed at the technologic therapeutic patterns of the the Institute of Oncology and Radiobiology, of Havana City. (author).

164

Characterization of 3-["1"2"3I]iodo-L-#alpha#-methyl tyrosine (["1"2"3I]IMT) transport into human Ewing's sarcoma cells in vitro  

International Nuclear Information System (INIS)

3-["1"2"3I]Iodo-L-#alpha#-methyl tyrosine (["1"2"3I]IMT) scintigraphy of extracranial malignant tumors has been described, but little is known about the transport systems involved in ["1"2"3I]IMT uptake into extracranial tumor cells. Here, the precise kinetics of ["1"2"3I]IMT transport into human Ewing's sarcoma cells (VH-64) was determined. The apparent Michaelis constant was of high affinity value (K_m=41.7#+-#3.9 #mu#M) and maximum transport velocity amounted to V_m_a_x=20.7#+-#0.6 nmol#centre dot#mg protein"-"1#centre dot#10 min"-"1. Inhibition experiments revealed the predominance of ["1"2"3I]IMT uptake via sodium-independent system L.

2001-02-01

165

3-["1"2"3I]Iodo-L-#alpha#-methyl tyrosine transport into human fibroblasts and comparison with Ewing's sarcoma cells  

International Nuclear Information System (INIS)

The cellular transport systems and the transport kinetics of ["1"2"3I]IMT uptake into non-malignant extracranial cells were characterized for the first time. Human fibroblasts were chosen as non-malignant extracranial cells as they are found ubiquitous in the body. ["1"2"3I]IMT is exclusively transported into fibroblasts via the sodium independent system L. An apparent Michaelis constant K_m=116.2#+-#18.9 #mu#M and a maximum transport velocity V_m_a_x=191.6#+-#13.9 pmol * (10"6 cells)"-"1 * min"-"1 were calculated for the sodium-independent transport. These results were compared with those determined in two malignantly transformed extracranial cell lines, the human Ewing's sarcoma cell lines VH-64 and CADO-ES-1.

2002-05-01

166

The efficacy of low-dose radiation therapy and surgical resection for Ewing's sarcoma  

International Nuclear Information System (INIS)

Purpose: To evaluate the effect of low-dose radiation therapy and surgery on local control in patients with Ewing's Sarcoma. Materials and Methods: Between 1979 and 1995 24 patients (ages 4-47) with Ewing's sarcoma were treated with combined modality therapy that included multi agent chemotherapy, surgical resection, and radiation therapy. Twelve patients had metastatic disease at the time of presentation (pleura = 3, lung = 5, bone 4). Tumor location was central in 16 and peripheral in 8. Multi agent chemotherapy consisted of vincristine/actinomycin D/cyclophosphamide/doxorubicin in 19. The same agents with the addition of ifosfamide and etoposide were given in 5. The extent of resection was considered to be radical in 14 and of the 16 patients who received preoperative chemotherapy, 5 were found to have a pathologic complete response. All patients with lung metastases at diagnosis received whole-lung irradiation to 1400 cGy in 10 fractions. ...

1996-09-01

167

Primary Ewing's sarcoma of the vertebral column  

International Nuclear Information System (INIS)

To determine the demographics, imaging findings, clinical symptoms, and prognosis of primary vertebral Ewing's sarcoma (PVES). A retrospective review of medical records and radiological studies of patients diagnosed with PVES from 1936 through 2001 in our institution and Department of Pathology consultation files was undertaken. Metastatic and soft tissue Ewing's sarcoma cases were excluded. From a total of 1,277 cases of Ewing's sarcoma, 125 (9.8%) had a primary vertebral origin. There were 48 females and 76 males. Patient ages ranged from 4 to 54 (mean 19.3, standard deviation 10.7, median 16) years. Vertebral column distribution was four cervical (3.2%), 13 thoracic (10.5%), 31 lumbar (25%), and 67 sacrum (53.2%). More than one vertebral segment was involved in ten cases (8%). Satisfactory imaging studies were available in 51 patients: 49 radiographs, 27 computerized tomography (CT), and 23 magnetic resonance imaging ...

2004-09-01

168

Irradiation by carbon ions?: why? How?; Irradiation par ions carbone: pourquoi? Comment?  

Energy Technology Data Exchange (ETDEWEB)

The interest of irradiation by carbon ions is in the fact that the carbon ions leave all their energy to a determined depth. ( phenomenon known under the name of Bragg peak)This high diffusion in tissue gives an RBE particularly high. The indications of this therapy are chordomas, and chondrosarcomas of the skull base, some cyst adenoid carcinomas, pulmonary cancer, sarcomas, hepato carcinomas, melanomas. In the light of results in term of efficiency, the place of irradiation by carbon ions should widen. (N.C.)

2006-11-15

169

Imaging findings of abdominal peripheral primitive neuroectodermal tumor: report of four cases with pathological correlation  

British Library Electronic Table of Contents (United Kingdom)

Peripheral primitive neuroectodermal tumors (peripheral PNETs) are rare in the abdomen. We report the imaging findings of four peripheral PNETs arising in the abdomen. Three were ill-demarcated tumors and one was a well-demarcated tumor, with extensive local invasion and lymph node metastasis in two cases, respectively. The tumors are of inhomogeneous attenuation and heterogeneous enhancement after intravenous administration of contrast materials. Although their imaging manifestations cannot distinguish them from other sarcomas, recognition of these imaging features may be helpful in suggesting the possibility of peripheral PNETs in some cases.

2009-01-01

170

Dual-field rotational (DFR) technique for total-skin electron-beam therapy (TSEBT)  

Energy Technology Data Exchange (ETDEWEB)

Comparison of dosimetry measured in a noncylindrical Rando-Alderson phantom by two-field, four-field, and six-field total-skin electron-beam therapy (TSEBT) techniques with our dual-field rotational (DFR) technique reveals a superior dosimetry for the latter. Our technique of dual-field rotational DFR-TSEBT is described in detail, and its advantages and indications for the primary management of cutaneous T-cell lymphoma (CTCL) and Kaposi's sarcoma (KS) are discussed.

1987-08-01

171

Radiotherapy versus surgery in good-risk Ewing's sarcoma. An analysis of the CESS 86-data  

International Nuclear Information System (INIS)

The evaluation of radiotherapy and surgery as exclusive local treatment in comparably selected subgroups of patients with Ewing's sarcoma on the basis of the CESS 86-data. In the German multicenter Ewing's sarcoma study CESS 86, treatment consisted for four 9-week-courses of VACA- or VAIA-chemotherapy plus local therapy. VACA (vincristine, actinomycin D, cyclophosphamide, adriamycin) was given in low-risk extremity tumors with a tumor volume below 100 cm"3. Highrisk patients with central lesions or a tumor volume >100 m"3 received VAIA (ifosfamide instead of cyclophosphamide). Local therapy started after one complete chemotherapy course in week 10. Based on an individual decision in each patient, local therapy was either radical surgery or resection plus postoperative irradiation with 45 Gy or definitive radiotherapy with 60 Gy. Because of poor results with radiotherapy in a preceeding study, it was intended to restrict irradiation to ...

172

Radiotherapy in Ewing's sarcoma and PNET of the chest wall: results of the trials CESS 81, CESS 86 and EICESS 92  

International Nuclear Information System (INIS)

Purpose: Treatment results and the pattern of relapse were evaluated in the multimodal treatment of Ewing's sarcomas of the chest wall. Methods and Materials: In a retrospective analysis, 114 patients with non-metastatic Ewing's sarcoma of the chest wall were evaluated. They were treated in the CESS 81, CESS 86, or EICESS 92 studies between January 1981 and December 1993. The treatment consisted of polychemotherapy (VACA, VAIA, or EVAIA) and local therapy, either surgery alone (14 patients), radiotherapy alone (28 patients) or a combination of both (71 patients). The median follow-up was 46.6 months (range 5-170). A relapse analysis for all patients with local or combined relapses was performed. Results: Overall survival was 60% after 5 years, event-free survival was 50%. Thirty-seven patients had a systemic relapse (32.4%), 11 patients had a local relapse alone (9.6%), and 3 patients had a combined local and systemic relapse (2.6%). The risk ...

1998-12-01

173

Monitoring the effect of chemotherapy in Ewing's sarcoma of bone with MR imaging  

International Nuclear Information System (INIS)

Magnetic resonance (MR) imaging was performed in 26 patients with Ewing's sarcoma of bone preceding and following neoadjuvant chemotherapy, to assess tumour response non-invasively prior to surgery. T1- and T2-weighted spin echo images were obtained. Changes including intra- and extramedullary signal intensities, tumour demarcation, tumour volume and the appearance of residual extramedullary tumour were compared with histophathology of the resected specimens. Reduction of tumour volume was significantly higher in good responders. Other single parameters did not correlated with histologic tumour response. However, when several MR parameters summarized in a classification system were combined, a positive correlation with histopathologic response was found. A limited decrease of tumour volume (<25 %) and/or residual soft tissue mass following chemotherapy correlated with a poor response. An inhomogeneous, well-defined cuff of abnormal tissue encircling the bone ...

174

Lung irradiation for Ewing's sarcoma with pulmonary metastases at diagnosis: results of the CESS-studies  

International Nuclear Information System (INIS)

Background: In the German CESS-studies, Ewing's sarcoma patients with pulmonary metastases at diagnosis were considered as candidates for additional bilateral lung irradiation. We have retrospectively analyzed the impact of radiotherapy on survival. Material and methods: Out of 42 patients presenting with pulmonary metastases of Ewing's sarcoma between 1981 and June 1992, 30 were evaluable. One patient died of progressive disease prior to lung irradiation. The other patients had a complete radiographic remission either after chemotherapy (n=25) or chemotherapy plus resection of lung metastases (n=4). 22 patients received bilateral lung irradiation with doses of 12 to 21 Gy (once daily 1.5 Gy or twice daily 1.25 Gy), six had no further treatment and one had bone marrow transplantation for consolidation. Results: Ten patients are in complete remission, nine of them had received lung irradiation and one had a complete resection of three lung ...

175

Long-term results in 144 localized Ewing's sarcoma patients treated with combined therapy  

International Nuclear Information System (INIS)

The results of 144 previously untreated cases of primary Ewing's sarcoma of bone are reported with a minimum follow-up of 5 years. This series was treated between 1972 and 1982 at Istituto Ortopedico Rizzoli with a combined therapy. The local control of the disease consisted of amputation (ten cases), resection followed by radiation therapy (35-45 Gy) (48 cases) and radiation therapy alone (40-60 Gy) (86 cases). Adjuvant chemotherapy, rigorously standardized, was performed according two different protocols: the first (85 cases treated in the period 1972-1978) consisted of vincristine (VCR) Adriamycin (doxorubicin) (ADM), and cyclophosphamide (EDX); the second (59 cases treated in the period 1979-1982) of VCR, ADM, EDX and dactinomycin (DACT). At a follow-up of 5 to 16 years (median, 9), 59 patients (41%) are continuously disease-free (CDF), 81 (56%) developed metastatic disease and/or local recurrence, and four (3%) had a second malignancy. Three factors seem to be ...

176

Intensive combined modality therapy including low-dose TBI in high-risk Ewing's sarcoma patients  

International Nuclear Information System (INIS)

Twenty-four high-risk Ewing's sarcoma patients were treated on an intensive combined modality protocol including low-dose fractionated total body irradiaiton (TBI) and autologous bone marrow infusion (ABMI). Twenty patients (83%) achieved a complete clinical response to the primary and/or metastatic sites following induction therapy. The median disease-free interval was 18 months, and nine patients remain disease-free with a follow-up of 22 to 72 months. Local failure as a manifestation of initial relapse occurred in only three patients (15%), each having synchronous distant failure. Eight patients failed initially with only distant metastases, usually within 1-2 years following a complete clinical response. Two patterns of granulocyte recovery following consolidative therapy (including TBI and ABMI) were recognized. The time to platelet recovery was different for the groups with early and late granulocyte recovery. Patients with late recovery did not tolerate ...

177

The Muhlbauer method for pipeline risk management in onshore environment; O metodo de Muhlbauer para gerenciamento de risco em linhas de dutos em ambiente 'onshore'  

Energy Technology Data Exchange (ETDEWEB)

There are several methods for the risk assessment and risk management applied to pipelines, among them the Muhlbauer's Method. W. Kent Muhlbauer is an internationally recognized authority on pipeline risk management. He made a detailed identification about 300 distinct conditions that influence the risk assessment in pipelines and he proposed a score system that is known as method of Muhlbauer. The purpose of this model is to evaluate the public exposure to the risk and identify ways for management that risk in fact. The assessment is made by the attribution of quantitative values to the several items that influences in the pipeline risk. This paper approaches the Muhlbauer's basic model for risk assessment and management in pipelines. In the beginning, the basic model for risk assessment is presented, and methodology for pipelines in onshore environment is detailed. After, presents major items in risk assessment and this relative score. Finally, present the ...

2008-07-01

178

Pressure based leak detection system implanted on the business Unit Exploration and Production of PETROBRAS in Rio Grande do Norte e Ceara; Sistema de deteccao de vazamentos em dutos baseado em pressao implantado na Unidade de Negocios de Exploracao e Producao da PETROBRAS no Rio de Grande do Norte e Ceara  

Energy Technology Data Exchange (ETDEWEB)

This paper presents the experience faced by people who works in PETROBRAS Business Unit (UN-RNCE), located in Rio Grande do Norte Province, Brazil, during the implementation of a pipeline leak detection system. That application involved nine multiphase oil pipelines distributed along several production facilities. Because of the emergency after the leakage that polluted the Guanabara bay and due to the two phases and multi phases pipelines characteristics, the UN-RNCE decided to apply the Pressure Point Analysis (PPA) technology in order to detect leakages. It is a statistical method for leak detection e uses a very simple instrumentation which facilitates the installation and maintenance. However, in order to get the best performance of the system, it is necessary to know thoroughly the whole process and have a fast and reliable SCADA system for long distance communication. Finally it will be shown the test results, the recommendations to expand the system and the conclusions. ...

2003-07-01

179

Observational approach implementation guidance: Year-end report  

Energy Technology Data Exchange (ETDEWEB)

It is generally recognized that the Remedial Investigation/Feasibility Study (RI/FS) process can be time-consuming and costly. To expedite the process, the Environmental Protection Agency, through the National Contingency Plan and Office of Solid Waste and Emergency Response (OSWER) Directives, has promoted streamlining'' the RI/FS. The concept of streamlining is directly applicable to Resource Conservation and Recovery Act (RCRA) Remedial Facility Investigation/Corrective Measure Study (RFI/CMS) as well. The US Department of Energy's (DOE's) environmental restoration process promises to be lengthy and expensive: therefore, the Office of Environmental Restoration (EM-40) believes that it is to incorporate streamlining into RI/FS and RFI/CMS efforts across the DOE complex. The Office of Program Support (EM-43) has asked Pacific Northwest Laboratory (PNL) to provide presentations and workshops on streamlining ...

1992-06-01

180

Integrated thermal and nonthermal treatment technology and subsystem cost sensitivity analysis  

Energy Technology Data Exchange (ETDEWEB)

The U.S. Department of Energy`s (DOE) Environmental Management Office of Science and Technology (EM-50) authorized studies on alternative systems for treating contact-handled DOE mixed low-level radioactive waste (MLLW). The on-going Integrated Thermal Treatment Systems` (ITTS) and the Integrated Nonthermal Treatment Systems` (INTS) studies satisfy this request. EM-50 further authorized supporting studies including this technology and subsystem cost sensitivity analysis. This analysis identifies areas where technology development could have the greatest impact on total life cycle system costs. These areas are determined by evaluating the sensitivity of system life cycle costs relative to changes in life cycle component or phase costs, subsystem costs, contingency allowance, facility capacity, operating life, and disposal costs. For all treatment systems, the most cost sensitive life cycle phase is the operations and maintenance phase and the ...

1997-02-01

181

Integrated EM & Thermal Simulations with Upgraded VORPAL Software  

Energy Technology Data Exchange (ETDEWEB)

Nuclear physics accelerators are powered by microwaves which must travel in waveguides between room-temperature sources and the cryogenic accelerator structures. The ohmic heat load from the microwaves is affected by the temperature-dependent surface resistance and in turn affects the cryogenic thermal conduction problem. Integrated EM & thermal analysis of this difficult non-linear problem is now possible with the VORPAL finite-difference time-domain simulation tool. We highlight thermal benchmarking work with a complex HOM feed-through geometry, done in collaboration with researchers at the Thomas Jefferson National Accelerator Laboratory, and discuss upcoming design studies with this emerging tool. This work is part of an effort to generalize the VORPAL framework to include generalized PDE capabilities, for wider multi-physics capabilities in the accelerator, vacuum electronics, plasma processing and fusion R&D fields, and we will also discuss user ...

2011-03-01

182

Implementation of the DOE Office of Technology Development Strategic Program Plan for Environmental Education and Development  

Energy Technology Data Exchange (ETDEWEB)

With the November 1989 formation of the Office of Technology Development (OTD) within the Office of Environmental Restoration and Waste Management (EM) came the responsibility to develop programs to ensurethat enough trained and educated people would be available to support the achievement of EM's 30-year goal. This mission responsibility derives from public policy and Departmental environmental management requirements. Within DOE, urgency to move forward resulted from the assumptions (1) that the current workforce was insufficiently prepared for the transition from a production mission to a mission of environmental compliance and cleanup; and (2) that, given current trends and forecasts, the national education infrastructure was unlikely to yield the scientists, engineers, and technicians to meet future DOE workforce needs, especially in the case of women and minorities who, projected to make up two-thirds of the net entering ...

1992-01-01

183

Electron momentum spectroscopy of H_2 and D_2: Ionization to ground and excited final states  

International Nuclear Information System (INIS)

The symmetric noncoplanar (e,2e) cross sections (momentum profiles) of H_2 and D_2 for the transitions to the 2p#sigma#_u and 2s#sigma#_g excited ion states have been measured, relative to the ground-state ion transition, using a high-sensitivity multichannel momentum-dispersive electron momentum spectrometer (EMS) at an impact energy of 1200 eV. Newly calculated plane-wave impulse approximation (PWIA) cross sections, based on a full-configuration-interaction H_2 wave function, are compared to the experimental results. These calculations are in better agreement with the experimental results for the transition to the 2s#sigma#_g ion state than the earlier theoretical work of Liu and Smith, Jr. [Phys. Rev. A 31, 3003 (1985)] which has been found to be in error. Nevertheless, significant discrepancies between the relative experimental and theoretical cross sections are observed for the transitions to excited ion states, suggesting a failure of the PWIA description of ...

184

EMS network security applications of the future  

Energy Technology Data Exchange (ETDEWEB)

Changes facing the electricity supply industry are significant, and the challenges these changes pose are enormous. There are major changes to the business environment of transitional electric utilities. There are also changes in the management of the companies in that nontechnical people are taking over the leadership of traditionally technical companies to deal with the new business scenario. This raises the concern that there may be a lack of familiarity by management of the technical issues involved with the result that the quality of the product may be at risk over the long term. This article deals with the future. It describes a vision for the control center energy management systems (EMS) network security applications as a function of the current and expected changes in the electric supply industry. The objective is to present a conceptual specification. It suggests possible approaches to the problems control centers are likely to encounter in the future. ...

1996-04-01

185

Correlation between designed wall thickness of gas pipelines and external and internal corrosion processes; Adequacao de espessura de parede projetada em funcao de processos de corrosao externa e interna em gasodutos  

Energy Technology Data Exchange (ETDEWEB)

Corrosion control on gas pipelines plays an important role on the assessment of pipeline integrity and reliability. In many countries a great extension of buried pipelines is used on transport and distribution systems. This extension will be certainly increased in a near future due to the increasing consumption of natural gas. Inadequate corrosion control can drive to pipeline failures, bringing up the possibility of accidents in populated or environmental protected areas, bringing together severe economical, legal and environmental consequences. Corrosion is frequently considered as a natural and inevitable phenomenon. Based upon this assumption, some recommendations are included on design standards of gas pipelines in order to compensate its detrimental effect. The aim of this work is to present a review of the correlation between external corrosion process and the guidelines established during the project phase of gas pipelines. It is intended to contribute for a better ...

2004-07-01

186

Collective behavior of stock price movements in an emerging market  

CERN Document Server

To investigate the universality of the structure of interactions in different markets, we analyze the cross-correlation matrix ${\\mathbf C}$ of stock price fluctuations in the National Stock Exchange (NSE) of India. We find that this {\\em emerging} market exhibits strong correlations in the movement of stock prices compared to {\\em developed} markets, such as the New York Stock Exchange (NYSE). This is shown to be due to the dominant influence of a common market mode on the stock prices. By comparison, interactions between related stocks, e.g., those belonging to the same business sector, are much weaker. This lack of distinct sector identity in emerging markets is explicitly shown by reconstructing the network of mutually interacting stocks. Spectral analysis of ${\\mathbf C}$ for NSE reveals that, the few largest eigenvalues deviate from the bulk of the spectrum predicted by random matrix theory, but they are far fewer in number compared ...

2007-01-01

187

A Wide-Band Electromagnetic Impedance Profiling System forNon-Invasive Subsurface Characterization  

Energy Technology Data Exchange (ETDEWEB)

A non-invasive, wide-band electromagnetic (EM) impedance difference system for shallow subsurface electrical structure characterization in environmental and engineering problems has been developed at the Lawrence Berkeley National Laboratory (LBNL). Electrical parameters of interest are electrical conductivity and dielectric permittivity that are deduced from the impedance difference data. The prototype system includes a magnetic loop transmitter, which operates between 0.1 MHz and 100 MHz, an electrical dipole antenna for observing the electric field, and a loop antenna for measuring the magnetic field.All antennas are mounted on a cart made of non-metallic material for easy movement of the whole array for profiling. Surface EM impedance difference is obtained by taking the difference of the ratios of the electric fields to the magnetic fields at selected frequencies at two different levels. Numerical simulations will be presented to verify ...

2004-12-17

188

A multidisciplinary study investigating radiotherapy in Ewing's sarcoma: end results of POG no. 8346  

International Nuclear Information System (INIS)

Purpose: To determine if involved field radiation (IF) is equivalent to standard whole bone radiation (SF) in local tumor control; to establish patterns of failure following treatment; and to determine response, event-free survival (EFS), and overall survival rates from multidisciplinary therapy in Ewing's sarcoma. Methods and Materials: Between 1983 and 1988, 184 children with Ewing's sarcoma were enrolled onto Pediatric Oncology Group 8346 (POG 8346). A total of 178 (97%) met eligibility criteria; 6 had pathology other than Ewing's sarcoma. Induction chemotherapy of cyclophosphamide/doxorubicin (adriamycin )(C/A) x 12 weeks was followed by local treatment either surgery or radiation therapy and C/A, dactinomycin, and vincristine for 50 weeks. Resection was advised for patients with small primary tumors if accomplished without functional loss. Forty patients were randomized to receive SF, whole bone radiation to 39.6 Gy ...

1998-08-01

189

Ultraviolet Complete Electroweak Model Without a Higgs Particle  

CERN Document Server

An electroweak model with running coupling constants described by an energy dependent entire function is utraviolet complete and avoids unitarity violations for energies above 1 TeV. The action contains no physical scalar fields and no Higgs particle and the physical electroweak model fields are local and satisfy microcausality. The $W$ and $Z$ masses are compatible with a symmetry breaking $SU(2)_L\\times U(1)_Y \\rightarrow U(1)_{\\rm em}$, which retains a massless photon. The vertex couplings possess an energy scale $\\Lambda_W > 1$ TeV predicting scattering amplitudes that can be tested at the LHC.

2010-01-01

190

The AMS-02 electromagnetic calorimeter  

CERN Document Server

The Electromagnetic Calorimeter (ECAL) of the AMS-02 experiment is a lead-scintillating fibers sampling calorimeter characterized by high granularity that allows to image the longitudinal and lateral showers development, a key issue to provide high electron/hadron discrimination. The light collection system and the FE electronics are designed to let the calorimeter operate over a wide energy range from few GeV up to 1 TeV. A full-scale prototype of the e.m. calorimeter was tested at CERN in October 2001 using electrons and pions beams with energy ranging from 3 to 100 GeV. Effective sampling thickness, linearity and energy resolution were measured. (8 refs).

2002-01-01

191

Ten-nanometer surface intrusions in room temperature silicon  

CERN Document Server

Defects ~10 nm in size, with number densities ~10^{10} cm^{-2}, form spontaneously beneath ion-milled, etched, or HF-dipped silicon surfaces examined in our Ti-ion getter-pumped transmission electron microscope (TEM) after exposure to air. They appear as weakly-strained non-crystalline intrusions into silicon bulk, that show up best in the TEM under conditions of strong edge or bend contrast. If ambient air exposure is <10 minutes, defect nucleation and growth can be monitored {\\em in situ}. Possible mechanisms of formation are discussed.

2002-01-01

192

Technical papers presented at the 4. symposium of specialists in electric operational and expansion planning. v. 2; Artigos tecnicos apresentados no 4. simposio de especialistas em planejamento da operacao e expansao eletrica. v. 2  

Energy Technology Data Exchange (ETDEWEB)

This symposium about electric operational and expansion planning presents several articles that approaches issues such as, monitoring the power system stability, electrical load modelling, reliability in power systems, optimization in power systems, integrated resources planning in power systems, reactive control through static compensators, power flow analysis, system modelling, etc

1994-12-31

193

Solenoid transport for heavy ion fusion  

Energy Technology Data Exchange (ETDEWEB)

Solenoid transport of high current, heavy ion beams is considered for several stages of a heavy ion fusion driver. In general this option is more efficient than magnetic quadrupole transport at sufficiently low kinetic energy and/or large e/m, and for this reason it has been employed in electron induction linacs. Ideally an ion beam would be transported in a state of Brillouin flow, i.e. cold in the transverse plane and spinning at one half the cyclotron frequency. The design of appropriate solenoids and the equilibrium and stability of transported ion beams are discussed. An outline of application to a fusion driver is also presented.

2004-06-15

194

Physics with Polarized Antiprotons  

Energy Technology Data Exchange (ETDEWEB)

Polarized antiprotons produced by spin filtering with an internal polarized gas target provide access to a wealth of single- and double-spin observables, thereby opening a window to physics uniquely accessible with the HESR at FAIR. This includes a first measurement of the transversity distribution of the valence quarks in the proton, and a first measurement of the moduli and the relative phase of the time-like electric and magnetic form factors G{sub E,M} of the proton. In polarized and unpolarized pp-bar elastic scattering open questions like the contribution from the odd charge-symmetry Landshoff-mechanism at large |t| and spin-effects in the extraction of the forward scattering amplitude at low |t| can be addressed.

2006-04-15

195

Niobium behaviour in liquid aluminium; Comportamento do niobio em aluminio liquido  

Energy Technology Data Exchange (ETDEWEB)

In this paper we studied the behavior of commercially pure niobium immersed in molten aluminum. The experiments were carried out 800 and 900 deg C during 2 to 128 hours. Chemical and metallographic analyses, as well as microhardness measurements of the niobium specimens were accomplished. An increase of niobium content in the aluminum bath with time was observed. Metallographic observations revealed the formation of Nb Al{sub 3} external intermetallic compound. During dissolution, fragments of this compound settled at the bottom of the crucible. This behaviour was also observed at 900 deg C, nevertheless with higher intensity. (author) 10 refs., 5 figs., 3 tabs.

1996-12-31

196

Material-not-categorized-as-waste survey for 1992  

Energy Technology Data Exchange (ETDEWEB)

In October 1992, the US Department of Energy, Richland Field Office (RL) requested that Westinghouse Hanford Company (WHC) respond to a letter from EM-331 asking for completion of a survey of items in storage but not categorized as waste (Roberts 1992). The letter contained an attachment with instructions on how to fill out the attached form and what to exclude from the survey (Appendix A). This report is a summary of the information from the response issued to RL. This report primarily is for use in estimating future waste volumes that may have been overlooked because of the nature of their classification as material not categorized as waste (MNCAW) (i.e., not yet declared Waste).

1993-07-01

197

Induced plasmon mutations affecting the growth habit of peanuts, A. hypogaea L  

International Nuclear Information System (INIS)

The effectiveness of the acridines ethidium bromide (EB) and acriflavine in inducing plasmon mutations was compared with the alkylating agents ethyl methanesulphonate (EMS) and diethyl sulphate and to #gamma#-rays. The growth habit (trailing versus bunch) of peanuts (A. hypogaea), controlled by genic-cytoplasmic interactions, was utilized. Breeding tests distinguishing nuclear from plasmon mutations were developed and are described in detail. Plasmon mutations were induced, but there were differences in mutation yields between the cultivars and the mutagens. (Auth.).

1978-01-01

198

Indirect stabilization of weakly coupled systems with hybrid boundary conditions  

CERN Document Server

We investigate stability properties of indirectly damped systems of evolution equations in Hilbert spaces, under new compatibility assumptions. We prove polynomial decay for the energy of solutions and optimize our results by interpolation techniques, obtaining a full range of power-like decay rates. In particular, we give explicit estimates with respect to the initial data. We discuss several applications to hyperbolic systems with {\\em hybrid} boundary conditions, including the coupling of two wave equations subject to Dirichlet and Robin type boundary conditions, respectively.

2011-01-01

199

Excitation of Plasma Fluctuations near ion Giro frequencies during RF Plasma Heating in URAGAN-3M Torsatron  

International Nuclear Information System (INIS)

Currentless plasma in Uragan-3M (U-3M) is produced and heated by absorption of RF power in the region of Alfven waves (AW). The process of plasma heating was explained in (2) as a result of Cherenkov absorption of energy of the fast (EM) and slow (kinetic Alfven) waves by electrons and turbulent ion heating due to excitation of short wave ion Bernstein waves (IBW). In this report we present results of studies of plasma density fluctuations showing existence of a narrow bands near the frequencies of ? ? n?ci (n=1,2,3).

2006-01-01

200

Equipment stainless steel entire versus steels bimetallics clad or overlay; Utilizacao de equipamentos de processo construidos em aco inoxidavel integral versus acos bimetalicos cladeado ou 'overlay'  

Energy Technology Data Exchange (ETDEWEB)

This study does not recommend the use of a pressure vessel made of integral stainless steel, due to the failure mechanisms under stress corrosion assisted by chlorides or polythionic acid. Are presented case studies of literature and analysis of reports of proceedings of RLAM reactors, showing that the materials produced by bimetallic clad overlay or are more appropriate, in terms of integrity, for use in equipment that the internal environment requires austenitic stainless steel specification.

2008-07-01

201

Electric induction on a trolley bus contact line, running parallel to a 138 KV overhead transmission line; Inducao em linha de contato de trolebus paralela a uma linha de transmissao de 138 kV  

Energy Technology Data Exchange (ETDEWEB)

Results obtained on induced current and voltage caused by a high voltage transmission lines running parallel at a trolley bus contact lines, are presented. A computer program in Basic language, was developed to calculate the electric induction, problems of safety, a theoretical development and mathematical model of the electric factors between two lines (inductor and induced) are also discussed. 11 figs., 1 tab., 8 refs.

1991-12-31

202

Determination of the semi-empiric relationship among the physical density, the concentration and rate between hydrogen and manganese atoms, and a manganese sulfate solution; Determinacao da relacao semi-empirica entre a densidade fisica, concentracao e razao entre atomos de hidrogenio e manganes em uma solucao de sulfato de manganes  

Energy Technology Data Exchange (ETDEWEB)

The bath of a manganese sulfate (BMS) is a system for absolute standardization of the neutron sources. This work establishes a functional relationship based on semi-empirical methods for the theoretical prediction of physical density values, concentration and rate between the hydrogen and manganese atoms presents in the solution of the BMS

2009-07-01

203

Radiation therapy in Ewing's sarcoma: an update of the CESS 86 trial  

International Nuclear Information System (INIS)

Purpose: We present an update analysis of the multiinstitutional Ewing's sarcoma study CESS 86. Methods and Materials: From January 1986 through June 1991, 177 patients with localized Ewing's sarcoma of bone, aged 25 years or less, were recruited. Chemotherapy consisted of four 9-week courses of vincristine, actinomycin D, cyclophosphamide, and adriamycin (VACA) in low-risk tumors (extremity tumors =# 100 cm"3). Local therapy was an individual decision in each patient and was either radical surgery (amputation, wide resection) or resection plus postoperative irradiation with 45 Gy or definitive radiotherapy with 60 Gy (45 Gy plus boost). Irradiated patients were randomized concerning the type of fractionation in either conventional fractionation (once daily 1.8-2.0 Gy, break of chemotherapy) or hyperfractionated split-course irradiation simultaneously with the VACA/VAIA chemotherapy (twice daily 1.6 Gy, break of 12 days after 22.4 Gy and 44.8 ...

1995-07-15

204

Local control and functional results after twice-daily radiotherapy for Ewing's sarcoma of the extremities  

International Nuclear Information System (INIS)

Purpose: Radiotherapy (RT) has been the predominant local treatment for Ewing's sarcoma of bone at the University of Florida. Twice-daily hyperfractionated RT was initiated in 1982 to improve local control and functional outcome. This retrospective review compares the results of once-daily vs. twice-daily RT in patients with primary Ewing's sarcoma of an extremity, with emphasis on functional outcome. Methods and Materials: Between June 1971 and January 1990, 37 patients were treated at the University of Florida for nonmetastatic Ewing's sarcoma of bone with a primary lesion in an extremity. Three patients underwent amputation. Of 34 patients treated with RT, 31 had RT alone and 3 had a combination of RT and local excision. Before 1982, 14 patients received once-daily RT; since 1982, 17 patients have received twice-daily RT. Doses of once-daily RT varied from 47 to 61 Gy at 1.8-2 Gy per fraction. Doses of twice-daily RT ...

1996-07-01

205

Health effects of the Chernobyl accident  

Energy Technology Data Exchange (ETDEWEB)

The results of nine years of study of the 237 patients who suffered from acute radiation syndrome (ARS) as a consequence of the Chernobyl accident are reported. Thirty-eight of these patients have died, 28 in the acute period in 1986, 5 in 1987-90 and 5 in 1992-93. The reasons for death show no clear tendencies. They include: gangrene of the lung, organic disease of the brain and spinal chord, hypoplasia of haematopoeisis, coronary heart disease, sarcoma and an automobile accident. Investigations have been carried out on an annual obligatory basis of the patients` haemopoietic, immune, nervous and endocrine systems. An analysis of the data is presented. Histograms are included showing the incidence of digestive tract, nervous system, respiratory and cardiovascular disorders, the frequency and degree of disablement and serum prolactin concentration. The types of skin damage sustained by 39 of the patients are listed. (6 figures, 3 tables). (UK).

1995-12-31

206

A new method in the management of skin neoplasm using a flexible radioactive patch  

Energy Technology Data Exchange (ETDEWEB)

We have developed a flexible radioactive polyurethane patch incorporating {beta}-emitting radionuclide (166Ho) to treat malignant skin lesions. We covered the tumor surface (n=133) with the radioactive patch for 33.58 {+-} 5.33 minutes. Radiation dose delivered was 35 Gy for Bowen's disease (n=78), Kaposi sarcoma (n=25), actinic keratosis (n=5), and 50 Gy for BCC (n=17) and squamous carcinoma (n=8). Complete response was observed in 91.7% after the first therapeutic trial, 96.2% after 2nd and 97.7% after 4th trial with excellent cosmetic outcome for 31.15{+-}13.88 months of follow-up. Radioactive patch therapy is effective for superficial skin cancers that are impractical for surgery.

2005-07-01

207

Viscosity of the Earth's inner core: Constraints from nutation observations  

British Library Electronic Table of Contents (United Kingdom)

The gravitational torque applied on the Earth by the other celestial bodies generates periodic variations in the orientation of the Earth's rotation axis in space which are called nutations. Observations of Earth's nutations allow for insights into the physical properties of the inner core because of the presence of a normal mode, the Free Inner Core Nutation (FICN), which is characterized by a tilt of the inner core figure and rotation axes with respect to the mantle and outer core. The frequency of the FICN is controlled by the strength of the mechanical coupling acting at the inner core boundary (ICB) and by the ability of the inner core to deform under the action of centrifugal and gravitational forces. Attenuation of the FICN reflects energy dissipated by electromagnetic (EM) and visc...

2011-01-01

208

Unravelling the complexity of collective mental models: A method for developing and analysing scenarios in multi-organisational contexts  

British Library Electronic Table of Contents (United Kingdom)

In multi-organisational contexts, scenario building has been used to engage stakeholders in a critical discussion on issues of mutual importance, and to gain their support with regards to possible future responses. A review of existing literature suggests that much has been written regarding the process of scenario development and the benefits of the process, but the detailed analysis of scenario building outcomes, which encompass a large number of issues and their complex interconnections, has not been made explicit for studying and enhancing understanding of a complex societal problem. This paper presents a systematic method for analysing such complex outcomes in order to facilitate reflective thinking on important issues within the wider context for policy development. The method was em...

2011-01-01

209

The use of domestic microwave oven in experimental classes of organic chemistry: salicylaldehyde nitration; O uso de aparelhos de micro-ondas domesticos em aulas experimentais de quimica organica: nitracao de salicilaldeido  

Energy Technology Data Exchange (ETDEWEB)

The use of microwave in chemistry has known benefits over conventional heating methods, e.g. reduced reaction times, chemical yield improvement and the possibility if reducing or eliminating the use of organic solvents. We describe herein a procedure for the nitration of salicylaldehyde in water using a domestic microwave oven, which can be used as an experiment in the undergraduate chemistry laboratory. The experiment involves safe and rapid preparation and identification of the position isomers by thin layer chromatography and {sup 1}H NMR, or by their melting points. (author)

2010-07-01

210

Surge pressure behavior in reduced diameter segments of shipping terminals; Comportamento de pulsos de pressao em trechos de diametro reduzido de dutos de terminais maritimos  

Energy Technology Data Exchange (ETDEWEB)

In a shipping terminal, the pipeline in the pier usually has a diameter smaller than the main pipeline diameter. This diameter reduction amplifies the effects caused by hydraulic transients. It was noticed during simulations that check valves placed in the pier may introduce some error in the maximum pressure when it was modeled in a conventional fashion. The dynamic check valve model had been added to a commercial pipeline simulation software and the results was compared with a similar model using the method of characteristics. Considering a real state shipping terminal case, it was proved even a pipeline that works with low pressure and smooth elevation profile needs a detailed valve modeling to prevent the calculation of unreal pressure values in the region with diameter reduction. (author)

2004-07-01

211

Some preliminary views of plasma interaction: electromagnetic-launch systems  

Energy Technology Data Exchange (ETDEWEB)

This discussion outlines a few areas of fundamental research which appear vital for progress in developing advanced propulsion concepts using dc railgun thrusters. We have placed emphasis on the following: (1) dense plasma and high current density influences on changes in microstructure and properties of conventional rail conductors such as Cu, Al, and W alloys or composites; (2) the influences described in (1) on more advanced high temperature, microstrain resistant, materials such as amorphous tungsten; (3) location, description and temporal evolution of current, magnetic field, and losses during intense plasma-current field interactions with conductors; and (4) composite materials and sequentially sectioned structures for more efficient EM dc launcher configuration.

1982-07-14

212

Simulation of the New York Power Pool for dispatcher training  

Science.gov (United States)

This paper describes the simulation of the operating environment of the New York Power Pool (NYPP) within the Dispatcher Training Simulator facility at the New York State Electric and Gas Corporation (NYSEG). The NYSEG control center uses real-time data received from the NYPP control center to control its internal generation. In addition, the NYSEG dispatchers work very closely with the NYPP dispatchers. The exact emulation of the Generation Control functions of the NYPP EMS, and the associated data exchange with the NYSEG ECS, contribute greatly to the high degree of realism achieved in the NYSEG DTS facility. The accuracy of the power system simulation in the DTS has been validated against actual power system disturbances recorded at NYSEG.

1994-11-01

213

Predictability, complexity and learning  

CERN Document Server

We define {\\em predictive information} $I_{\\rm pred} (T)$ as the mutual information between the past and the future of a time series. Three qualitatively different behaviors are found in the limit of large observation times $T$: $I_{\\rm pred} (T)$ can remain finite, grow logarithmically, or grow as a fractional power law. If the time series allows us to learn a model with a finite number of parameters, then $I_{\\rm pred} (T)$ grows logarithmically with a coefficient that counts the dimensionality of the model space. While logarithmic growth of related information theoretic quantities has been found in previous work on learning, power law growth has not been seen in this context. We find that it is associated, for example, with the learning of infinite parameter (or nonparametric) models such as continuous functions with smoothness constraints. There are connections between the predictive information and measures of complexity that have been defined both in ...

2000-01-01

214

Optimized sizing model for renewable energy systems in rural areas; Modelo de dimensionamento otimizado para sistemas energeticos renovaveis em ambiente rurais  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this research was to develop a methodology for sizing integrated renewable energy systems, useful for rural areas, using simulation and optimization tools developed in MATLAB 6.0. The sizing model produces a system with minimum cost and high reliability level, based on the concept of loss of power supply probability (LPSP) for consecutive hours. An optimization model is presented and three different sizing scenarios are calculated and compared, showing flexibility in the elaboration of different project conceptions. The obtained results show a complete sizing of the energy conversion devices and a long-term cost evaluation. (author)

2005-05-15

215

Natural gas utilization in blast furnace of non-integrated pig-iron plants; Utilizacao de gas natural em altos fornos de usinas siderurgicas nao-integradas  

Energy Technology Data Exchange (ETDEWEB)

In this paper, the authors investigate the technical and economical aspects of the natural gas injection in non-integrated pig-iron plants using charcoal in the blast furnace. The effects of the natural gas injection concerning the blast furnace flame temperature, charcoal consumption, productively and permeability are analyzed. It was found that the injection is beneficial in many ways, such as in the improvement of the productivity and quality, if the flame temperature is kept within an appropriate range. In the financial-economic project`s evaluation, the cash flow for the natural gas injection was analysed considering two blast conditions: through the drying and oxygen enrichment of the air. A sensibility analysis is presented in which the internal rate of return of the investment varies according to the prices of charcoal and oxygen. 3 refs., 3 figs., 3 tabs

1990-12-31

216

Modelling and migration of seismic data in transversely isotropic media; Modelamento e migracao de dados sismicos em meios transversalmente isotropicos  

Energy Technology Data Exchange (ETDEWEB)

The forward modelling and the prestack reverse time migration of seismic P-SV wave field was carried out in 2-D models of isotropic and anisotropic media which allow separation of P-SV and SH motion. The P-SV wave field can be described by a system of hyperbolic, first order differential equations in terms of particle velocity and stress. The system of five equations and five unknowns, namely horizontal (U) and vertical (V) velocity components, and three components of stress (T{sub xx}, T-z{sub z} and T{sub xz}) was solved numerically using second order space and forth order time finite differences operators. In order to attenuate numerical dispersion, a staggered grid was used. (author). 48 refs., 5 figs

1993-12-31

217

Implantation of an electronic system for real time neutron graphic images acquisition at the IPEN/CNEN Argonaut reactor; Implantacao de um sistema eletronico para aquisicao de imagens neutrongraficas em tempo real no reator Argonauta do IEN/CNEN  

Energy Technology Data Exchange (ETDEWEB)

The aim of this work is the implantation and characterization of a neutron radiography system that uses an electronic device for attainment of images in real time, for its implementation in the nuclear research reactor Argonauta at IEN/CNEN (Nuclear Engineering Institute of the Brazilian Nuclear Energy Commission). The Electronic Imaging System in Real Time is composed by a scintillator screen for neutron, a video camera (CCD), a digital plate and a computer with specific computational programs for digital processing of the images. The System in installed real time is apt to carry through neutron radiography inspections of static and dynamic events of several types of samples. (author)

2004-04-15

218

Fusion of protoplasts with irradiated micro protoplasts as a tool for radiation hybrid panel in citrus;Fusao de protoplastos com microprotoplastos irradiados como ferramenta para painel hibrido de radiacao em citros  

Energy Technology Data Exchange (ETDEWEB)

The objective of this work was to combine asymmetric somatic hybridization (donor-recipient fusion or gamma fusion) to microprotoplast-mediated chromosome transfer, as a tool to be used for chromosome mapping in Citrus. Swinglea glutinosa micro protoplasts were irradiated either with 50, 70, 100 or 200 gamma rays and fused to cv. Ruby Red grapefruit or Murcott tangor protoplasts. Cell colonies were successfully formed and AFLP analyses confirmed presence of S. glutinosa in both 'Murcott' tangor and 'Ruby Red' grapefruit genomes. (author)

2009-12-15

219

Free electron laser: general concepts and present state of practical importance  

International Nuclear Information System (INIS)

Since the advent of the first free electron laser (FEL) in 1976 up to now, a series of principles, configurations and operation modes of these FELs have been devised and partially implemented. The principles refer to transverse FEL, longitudinal FEL, combined FEL, and transverse optical klystron FEL. Configurations may be standard or many-stage and the undulators may be magnetostatic, electrostatic or electromagnetic. The operation regimes may be low-gain Compton type, high-gain Compton type, Raman type, with and without space charge. The operation modes may be the amplification of an external coherent EM radiation, a self-amplified spontaneous emission (SASE), or an oscillator. The paper presents in detail these concepts and the limit between classical approach and the quantum approach of FEL. (Author).

1994-09-21

220

Extended cognition and the space of social interaction  

British Library Electronic Table of Contents (United Kingdom)

The extended mind thesis (EM) asserts that some cognitive processes are (partially) composed of actions consisting of the manipulation and exploitation of environmental structures. Might some processes at the root of social cognition have a similarly extended structure? In this paper, I argue that social cognition is fundamentally an interactive form of space management-the negotiation and management of "we-space"-and that some of the expressive actions involved in the negotiation and management of we-space (gesture, touch, facial and whole-body expressions) drive basic processes of interpersonal understanding and thus do genuine social-cognitive work. Social interaction is a kind of extended social cognition, driven and at least partially constituted by environmental (non-neural) scaffold...

2011-01-01

221

Exergy transfer in a porous rectangular channel  

British Library Electronic Table of Contents (United Kingdom)

Present paper is performed to investigate the heat and exergy transfer characteristics of forced convection flow through a horizontal rectangular channel where open-cell metal foams of different pore densities such as 10, 20 and 30PPI (per pore inches) were situated. All of the bounding walls of the channel are subjected to various uniform heat fluxes. The pressure drop and heat transfer characteristics are presented by two important parametric values, Nusselt number (NuH) and friction factor (f), as functions of Reynolds number (ReH) and the wall heat flux (q). The Reynolds number (ReH) based on the channel height of the rectangular channel is varied from 600 to 33 000, while the Grashof number (GrDh) ranged from approximately 105-107 depending on q. Based on the experimental data, new em...

2010-01-01

222

Estimating Field Volatility of Soil Fumigants Using CHAIN_2D: Mitigation Methods and Comparison Against Chloropicrin and 1,3-Dichloropropene Field Observations  

British Library Electronic Table of Contents (United Kingdom)

Academic, government, and industrial field researchers have generated a significant database of field studies of the volatility of soil applied fumigants. However, limited work exists in validating physical models against field volatility data sets and fully exploring the volatility parametric response surface. Field studies quantifying atmospheric flux for soil fumigants 1,3-dichloropropene and chloropicrin are validated against the United States Department of Agriculture (USDA Salinity Laboratory) soil physics model CHAIN_2D that was modified specifically for agronomic uses of soil fumigants. Comparison between model predictions and field observations for six unique field trials in five different states indicate that CHAIN_2D effectively captures the magnitude and duration of fumigant em...

2010-01-01

223

Embodied energy and emergy evaluation of a typical biodiesel production chain in China  

British Library Electronic Table of Contents (United Kingdom)

Biodiesel from non-grain feedstock has been considered as one of the proper substitutes for fossil fuels associated with a series of activities emerging in China in order to meet the resource shortage and develop the energy crops. This paper presents an ecological accounting framework based on embodied energy, emergy, and CO2 emission for the whole production chain of biodiesel made from Jatropha curcas L. (JCL) oil. The energy and materials invested in and CO2 emission from the whole process, including cropping, transportation, extraction, and production, are accounted and calculated. Also, EmCO2, the ratio of real CO2 released to the emergy-based sustainability indicator per joule biodiesel, is proposed in this paper to present a new goal function for low-carbon system optimization. Fina...

2011-01-01

224

Electromagnetic forming - a potentially viable technique for accelerator technology  

International Nuclear Information System (INIS)

Modern day accelerator development encompasses a myriad technologies required for their diverse needs. Whereas RF, high voltage, vacuum, cryogenics etc., technologies meet their functional requirements, high finish lapping processes, ceramic-metal joining, oven brazing, spark erosion or wire cutting etc., are a must to meet their fabrication requirements. Electromagnetic (EM) forming technique falls in the latter category and is developed as a special technology. It is currently catering to the development as a nuclear reactor technology, but has the potential to meet accelerator requirements too. This paper highlights the general principle of its working, simple design guidelines, advantages, and suggests some specific areas where this could benefit accelerator technologies

2003-02-03

225

Dynamic modelling of check valves in shipping terminals; Modelagem dinamica de valvulas de retencao em terminais maritimos  

Energy Technology Data Exchange (ETDEWEB)

As usual a shipping terminal contains a header and its diameter is smaller than the main pipeline diameter. This diameter reduction amplifies the effects caused by hydraulic transients. It was noticed during simulations that check valves without dynamic modeling may introduce some error in the maximum pressure results without a dynamic model approach. The current paper uses commercial pipeline simulation software to model the dynamic behavior of the check valves. It was studied the header diameter influence and how the check valve model type may change the maximum pressure in the pipeline. It was proved that even a pipeline that works with low pressure and small elevation drop needs a detailed valve modeling to prevent the calculation of unreal pressure values in the region with diameter reduction. (author)

2005-07-01

226

Determination of Ca, Cr, Cu, Fe, K, Mg, Na and Zn in Brazilian medicinal plants by neutron activation and atomic absorption; Determinacao de Ca, Cr, Cu, Fe, K, Mg, Na e Zn em plantas medicinais brasileiras por ativacao neutronica e absorcao atomica  

Energy Technology Data Exchange (ETDEWEB)

Medicinal plants are available in the markets in Belo Horizonte, Minas Gerais. The objective of this work is to investigate the Ca, Cr, Cu, Fe, K, Mg, Na e Zn concentrations in two lots of usually known diuretics plants (azeitona do mato, cabelo de milho, cavalinha, cervejinha do campo, chapeu de couro, congonha de bugre, marmelinho do campo and quebra pedra) bought with an interval of time - six months - between the purchases. The elemental concentrations were determined applying k{sub 0} instrumental neutron activation analysis and atomic absorption spectrophotometry analysis. (author)

2002-07-01

227

Assessment of the supramolecular structures presents into biological samples by SAXS technique;Avaliacao das estrutras supramoleculares presentes em amostras biologicas atraves da tecnica de SAXS  

Energy Technology Data Exchange (ETDEWEB)

In this work was made an assessment of the supramolecular structures presents into human breast tissue normal and pathological samples, as well as into two types of animals samples (tendon chicken and pork fat) using the small angle x-ray scattering (SAXS) technique. The scattering profiles of the samples were determined at the momentum transfer range O.150nm{sup -1}<=5:q(=4pi.sin({theta}/2)/{lambda})<=8.500nm{sup -1}. In this range, it was possible identify structures corresponding to collagen fibrils (glandular tissue) and to triacylglycerides (adipose tissue) from the correlation between the information extracted from the human breast tissues scattering profiles and those extracted from animals samples. (author)

2009-07-01

228

Antireflection coatings with FeSi2 layer: Application to spectrally selective infrared emitter  

British Library Electronic Table of Contents (United Kingdom)

We have developed efficient spectrally selective infrared (IR) emitters that can be utilized for thermophotovoltaic (TPV) power generation by using stainless steel (SUS304) substrates coated with b- FeSi2 thin films. To develop spectrally selective emitters, we theoretically propose antireflection (AR) coatings consisting of a single layer of a dielectric material having a high refractive index (~5) and are appropriate for use with metals such as stainless steels in the IR region. This type of AR coating is fabricated by sputtering a b- FeSi2 thin film on a polished SUS304 substrate. The reflectance in the IR region is successfully reduced to less than 10%. In addition, the AR properties are stable even at 700 K in air. Therefore, metals with AR coatings of b- FeSi2 can be applied to IR em...

2011-01-01

229

A contribution to the study of the thermal behavior and of the electric performance of squirrel-cage induction motors; Uma contribuicao ao estudo do comportamento termico e do desempenho eletrico de motores de inducao com rotor em gaiola  

Energy Technology Data Exchange (ETDEWEB)

A thermal-electric mathematical model for a squirrel cage induction motors which permits to specify the best motor for specific drive, under thermal and electric aspects based, only on manufacturer technical bulletins and technical information is presented. Changes of rotor parameters due Skin Effect and changes of winding resistances (both stator and rotor) with the temperature are considered. The accuracy of this model is appraised using experimental results. The thermal behavior and electric performance for some motors are obtained for continuos and intermittent duties with sinusoidal and non-sinusoidal voltages. (author)

1992-03-01

230

The role of surgical margins in treatment of Ewing's sarcoma family tumors: Experience of a single institution with 512 patients treated with adjuvant and neoadjuvant chemotherapy  

International Nuclear Information System (INIS)

Purpose: To evaluate the importance of surgical margins for local and systemic control of Ewing's sarcoma family tumors (ESFT). Methods and Materials: Between 1979 and 1999, 512 patients with ESFTs entered 4 different adjuvant and neoadjuvant studies performed at a single institution. Of these patients, 335 were treated with surgery alone (196) or surgery followed by radiotherapy at doses of 44.8 Gy (139). We compared their outcome with that of the 177 patients who were locally treated by radiotherapy at 60 Gy. Results: Local control (88.8% vs. 80.2%, p < 0.009) and 5-year disease-free survival (63.8% vs. 47.6%, p < 0.0007) were significantly better in patients treated with surgery and, among them, in those with adequate surgical margins (96.6% vs. 71,7%, p < 0.0008, and 69.6% vs. 46.3%, p < 0.0002). Nonetheless, better results were observed only in extremity tumors. Conclusions: Surgery is better than radiotherapy in cases of extremity ESFT with ...

2006-07-01

231

Renal artery stenosis after radiotherapy for Ewing's sarcoma  

International Nuclear Information System (INIS)

Background: the fact that therapeutic irradiation can induce significant stenosis in the arteries of the head, neck, and chest, as welt as in the aorta and the iliac arteries, is familiar in daily practice and well documented in the literature. By contrast, radiation-induced renal artery stenosis seems to be a less widely known complication. Patients and methods: the sudden onset of medically refractory arterial hypertension and coma in a 27-year-old man is reported, who had been treated at age 20 with chemotherapy and radiotherapy for Ewing's sarcoma in the lumbar region. This treatment had been performed at the hospital of Sion, Switzerland in 2001. Also, the relevant literature from 1965 to 2007 is reviewed to underscore various aspects of this problem and to demonstrate the clinical relevance of renal artery stenosis as a potential long-term sequela of radiotherapy. Conclusion: radiation-induced renal artery stenosis has only rarely been described in the ...

2008-09-01

232

Radiation therapy for Ewing's sarcoma: Results from Memorial Sloan-Kettering in the modern era  

International Nuclear Information System (INIS)

Purpose: To evaluate the outcomes of patients with Ewing's sarcoma family of tumors (ESFT) treated with modern radiotherapy techniques with MRI along with optimal chemotherapy. Methods and Materials: The records of all 60 patients with ESFT who received radiation to the primary site between 1990 and 2004 were reviewed. All patients received chemotherapy, including vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide. Radiation was used as the sole modality for local control in 31 patients and was given either before (n = 3) or after surgical resection (n = 26) in the remainder. All patients had MRI and CT scan-based treatment planning, and 43% received intensity-modulated radiation therapy. Radiation doses ranged from 30 Gy to 60 Gy (median, 51 Gy), and 35% received hyperfractionated radiotherapy. Results: Median age was 16 years (range, 2-40 years). Because of selection bias for radiotherapy, the majority of primary tumors were centrally located ...

2006-02-01

233

Prognostic factors in the treatment of Ewing's sarcoma  

International Nuclear Information System (INIS)

From 1981 up to February 1985, a total of 93 protocol patients entered the study CESS 81. The protocol recommended an initial 18-week period of polychemotherapy (VACA) followed by local therapy and two additional cycles of chemotherapy. Local therapy consisted either of radical surgery or of incomplete resection plus postoperative irradiation with 36 Gy or of radiotherapy alone (46 and 60 Gy). Centrally located lesions were always irradiated with 60 Gy. This article summarizes the data after 5 years. Data of 93 patients were analysed in October 1986 after a median follow-up of 37 months. The projected 5-year survival is 50%. The relapse rate was 42%, distant relapses occurred in 19%, local (plus distant) relapses in 23%. Most of the relapses occurred during the first 3 years of observation. Failure rate was high in patients undergoing irradiation alone (44%). Initial tumour mass (> 100 ml) and histopathologic response to initial chemotherapy were identified as major prognostic ...

234

Ewing's sarcoma family tumors of the humerus: Outcome of patients treated with radiotherapy, surgery or surgery and adjuvant radiotherapy  

International Nuclear Information System (INIS)

Background and purpose: Local treatment for non-metastatic Ewing's sarcoma family tumors (ESFTs) is controversial. Results achieved in a single institution in patients with ESFT of the humerus are presented. Materials and methods: Patients treated between 1983 and 2000 for ESFT of the humerus were included. The impact of local treatment (surgery, radiotherapy or both) on outcome was assessed. Results: 55 patients: 34 males (62%); 21 females (38%); mean age: 17.9 (range: 3-40). Local treatment: surgery in 27 patients (49%), radiotherapy in 17 (31%) and surgery followed by radiotherapy in 11 (20%). After a mean follow-up of 15 years (range: 7-25 years), 27 patients (49%) remained continuously disease free, 27 (49%) relapsed and one died of chemotherapy toxicity. The local recurrence rate was 13% overall: 18% (3/17) after radiotherapy, 7% (2/27) after surgery and 19% (2/11) after surgery followed by adjuvant radiotherapy (p = ns). On the contrary, the 10-year EFS ...

2009-11-01

235

Effects of postoperative adjuvant chemotherapy and radiotherapy on ovarian function in women undergoing treatment for soft tissue sarcoma  

Energy Technology Data Exchange (ETDEWEB)

Ovarian function was evaluated in 11 women 16 to 43 years of age at treatment who received doxorubicin, cyclophosphamide, and high doses of methotrexate with or without radiotherapy in adjuvant therapy of soft tissue sarcoma. Five women (16-33 yr old) who received chemotherapy alone or combined with radiotherapy only at sites distant from the ovaries (chest wall, thigh, and leg) had minimal menstrual irregularities or temporary cessation of menses during therapy; cyclic menses returned promptly after therapy. Gonadotropin levels (expressed as means +/- SD) (follicle-stimulating hormone (FSH), 10 +/- 15 mlU/ml; luteinizing hormone (LH), 10 +/- 4 mlU/ml) and 17 ..beta..-estradiol (E/sub 2/) levels (means +/- SD, 208 +/- 147 pg/ml) were normal. By contrast, 4 older women (ages 36-43 yr) who received similar treatment developd persistent amenorrhea with postmenopausal levels of gonadotropin (FSH, 109 +/- 29 mlU/ml; LH, 72 +/- 19 mlU/ml) and E/sub 2/ (19 +/- 8 pg/ml). ...

1981-12-01

236

Effects of postoperative adjuvant chemotherapy and radiotherapy on ovarian function in women undergoing treatment for soft tissue sarcoma  

Energy Technology Data Exchange (ETDEWEB)

Ovarian function was evaluated in 11 women 16 to 43 years of age at treatment who received doxorubicin, cyclophosphamide, and high doses of methotrexate with or without radiotherapy in adjuvant therapy of soft tissue sarcoma. Five women (16-33 yr old) who received chemotherapy alone or combined with radiotherapy only at sites distant from the ovaries (chest wall, thigh, and leg) had minimal menstrual irregularities or temporary cessation of menses during therapy; cyclic menses returned promptly after therapy. Gonadotropin levels (expressed as means +/- SD (follicle-stimulating hormone (FSH), 10 +/- 5 mlU/ml; luteinizing hormone (LH), 10 +/- 4 mlU/ml) and 17 beta-estradiol (E2) levels (means +/- SD, 208 +/- 147 pg/ml) were normal. By contrast, 4 older women (ages 36-43 yr) who received similar treatment developed persistent amenorrhea with postmenopausal levels of gonadotropin (FSH, 108 +/- 29 mlU/ml; LH, 72 +/- 19 mlU/ml) and E2 (19 +/- 8 pg/ml). Two additional ...

1981-12-01

237

Combined therapy of localized Ewing's sarcoma of bone: Analysis of results in 100 patients  

International Nuclear Information System (INIS)

From 1979 to 1986, 182 patients with biopsy proven diagnosis of Ewing's sarcoma of bone were observed. One hundred of the 182 patients (72 males, 28 females, median age 15.8 years) with localized disease and no previous treatment were treated with chemotherapy (VCR, ADM, CTX, D-ACT) for 15-18 months. Local treatment was radiotherapy (42 patients), surgery (31 patients), or a combination of both (27 pts). Radiation doses ranged from 45 to 64 Gy given with conventional fractionation. Median follow-up was 51.2 months (24-106). Overall and disease-free survival were, respectively, 58.7 and 42.6%. Resected patients tended to have a better local control (Surgery 93.6%, Surgery + Radiation therapy 92.6%, Radiation therapy 69.1%). Disease-free survival was significantly related to the volume of the primary tumor (bulky: 33.2%, not-bulky: 57.7%), to site (extremities 54.6%, central sites 16.6%, other sites 40.9%), and to local treatment (Radiation therapy 30.3%, Surgery + ...

238

Characterization of hyaluronate binding proteins isolated from 3T3 and murine sarcoma virus transformed 3T3 cells  

Energy Technology Data Exchange (ETDEWEB)

A hyaluronic acid binding fraction was purified from the supernatant media of both 3T3 and murine sarcoma virus (MSV) transformed 3T3 cultures by hyaluronate and immunoaffinity chromatography. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis resolved the hyaluronate affinity-purified fraction into three major protein bands of estimated molecular weight (M/sub r,e/) 70K, 66K, and 56K which contained hyaluronate binding activity and which were termed hyaluronate binding proteins (HABP). Hyaluronate affinity chromatography combined with immunoaffinity chromatography, using antibody directed against the larger HABP, allowed a 20-fold purification of HABP. Fractions isolated from 3T3 supernatant medium also contained additional binding molecules in the molecular weight range of 20K. This material was present in vanishingly small amounts and was not detected with a silver stain or with (/sup 35/S)methionine label. The three protein species isolated by ...

1987-06-02

239

Analysis of Result of Treatment of Ewing's Sarcoma  

International Nuclear Information System (INIS)

Total 125 patients with primary and metastatic Ewing's sarcoma were treated in various ways between 1963 to 1977. Patients were divided into 3 groups according to the treatment methods. Group 1 was nonprotocol patients with or without chemotherapy. Total 58 patients were entered. Group 1 was divided into 2 subgroups. 33 patients were treated locally without chemotherapy and 25 patients were treated with local therapy and nonprotocol chemotherapy. Group 2 was treated with local therapy and plus T-2 regimen multiagent chemotherapy. 29 patients were entered. Group 3 was treated with local therapy and T-6 regimen multiagent chemotherapy. 38 patients were entered. Local treatments for primary tumor were surgery and/or radiation therapy. Radiation dose ranged between 2,000 and 8,000 rad. Patients with pulmonary metastases received bilateral pulmonary RT. Local recurrence rate was analyzed according to treatment groups and was 16.8%. Total 15 yr survival was 33% and 8 yr ...

1984-06-01

240

Global positioning automatic vehicle location system  

Energy Technology Data Exchange (ETDEWEB)

Los Alamos National Laboratory (LANL) is a unique facility covering over 43 square miles. The Emergency Management and Response Office (EM&R) is required to respond, provide Incident Command (IC), and coordination for all Laboratory emergencies. This requires IC`s and support staff to respond to the actual scene of the incident. Since the IC is under numerous constraints and stress, the office wanted the capability of locating the EM&R vehicles on an electronic map. An automated vehicle location (AVL) system was required for the additional safety of the emergency response personal. The requirements for the AVL system include total automatic tracking and low cost. After careful consideration, it was determined that the most efficient and cost effective system would be based on packet radio technology as the transmission media. The location is determined by the Department of Defense Global Positioning System (GPS). The system that was ...

1997-03-01

241

Energy use in swine unit in the finishing system with waste treatment; Uso de energia em unidade suinicola em sistema de terminacao com tratamento de residuos  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to assess the energy flux and energetic balance related to the swine production and the recycling of residues generated by the system for utilization as organic fertilizers. The experiment was carried out at Vale dos Ipes Farm, located in the city of Ouro Verde do Oeste, in the Western of Parana State. One finishing phase swine unity containing 600 animals was monitored from January to June 2005. The treatment system is composed by one steel digester with capacity for 50 m{sup 3}, one sedimentation tank, one algae tank and one bio fertilizer storage tank. The swine barn cleaning is performed by dry scratching on a daily basis. The generated residues flow by gravitation through ducts towards the digester. The duration of the hydraulic retention period was 12 days. In the calculation of energetic efficiency, the energetic component ration is the greatest energetic cost in production system of finishing phase swine, corresponding to 95% from the total direct ...

2006-07-01

242

Mesenchymal tumors of the pancreas. CT patterns; Tumori mesenchimali del pancreas: aspetti con tomografia computerizzata  

Energy Technology Data Exchange (ETDEWEB)

Purpose of this item is to report the CT patterns of pancreatic mesenchymal lesions and to investigate the capabilities and limitations of this technique in terms of characterization. In selected cases, CT can provide virtually diagnostic information (lipoma and teratoma), or at least highly suggestive findings (NHL, plexiform neurofibroma, lymphangioma). Moreover, knowledge of the variable morphostructural patterns of mesenchymal hisototypes (SCH, Sarcoma etc.) permits to include them in the differential diagnosis of pancreatic masses. [Italian] Scopo di questo rapporto e' descrivere gli aspetti semeiologici dei tumori mesenchimali del pancreas con la TC verificandone le possibilita e i limiti per la caratterizzazione. Pur nella rarita' dei reperti considerati, la TC puo' consentire l'effettiva caratterizzazione in alcuni casi (lipoma, neurofibroma plessiforme, linfangioma) o includere anche istotipi meno comuni (Schwannoma, ...

1999-10-01

243

Long-term IL-2 therapy after transplantation of T cell depleted stem cells from alternative donors in children  

British Library Electronic Table of Contents (United Kingdom)

The aim of this pilot study was to evaluate the feasibility of long-term subcutaneous application of low-dose IL-2 in children with malignancies at very high risk of relapse who underwent highly T cell and B cell depleted HLA-identical (MUD) or full haplotype mismatched related hematopoetic stem cell transplantation. We studied 11 patients with acute leukemias/myelodysplastic syndrome and juvenile myelomonocytic leukemia (active disease and/or second stem cell transplantation, n = 8; >=CR 2, n = 2) and relapsed or progressive Ewings sarcoma (n = 2) who received prophylactic IL-2 treatment for a high probability of disease recurrence after allo-HSCT. Toxicities from IL-2 were transient fever, fatigue and local inflammation. In one patient GvHD grade III with no clear association to IL-2 adm...

2011-01-01

244

An evaluation of the pendulum technique of electron beam therapy  

International Nuclear Information System (INIS)

Electron beam therapy of lesions such as cutaneous metastatic carcinoma and reticulum cell sarcoma is performed via multiple portals for a wide irradiation field. However, the dose distribution in border areas is generally uneven, resulting in hot and cold dose areas depending on the intervals of the portals. We performed electron irradiation by the pendulum technique, especially on curved areas, and evaluated the technique in various respects. Pendulum electron beam irradiation is indicated when the length of the cone must be reduced in order to deliver the target volume near the skin surface as well as to avoid the occurrence of hot spots deep in the body. We prepared a 15cm rotating cone by cutting a 30cm fixed irradiation cone. The modification posed no disadvantages in terms of extent and flatness of the beam, or stability during rotation. After determining the relationship between the rotation speed and the dose, the technique was successfully applied to a ...

245

Evolution of improved varieties of sesame through induced mutations  

International Nuclear Information System (INIS)

Sesame varieties/genotypes showed a good response to radiation with gamma rays and treatments with EMS. In M_1 both gamma rays and EMS influenced germination, seedling height, survival of plants and pollen fertility/sterility, producing deleterious effects on these characters. Compared to black seeded genotypes, white seeded ones are more susceptible to radiation. Both gamma rays and EMS produced various types of morphological variations in M_2 generation. These were dwarf plant mutants, mottled and fleshy leaved mutants (sterile), fasciated stem, flower colour, altered phyllotaxy, early, uniculm, capsule size variations, multiple capsule/leaf axil, seed coat colour variations, indehiscent and semi-indehiscent type mutants. Moreover, studies on quantitative characters including seed yield revealed the induction of mutants in both positive and negative directions for such traits which made a good scope of selection of ...

2001-01-01

246

Cutaneous and subcutaneous Ewing's sarcoma: an indolent disease  

International Nuclear Information System (INIS)

Purpose: The occurrence of extraosseous Ewing's sarcoma (ES) in deep soft tissues has been well described, but cases in which this tumor occurs in a primary cutaneous or subcutaneous site have rarely been reported. The superficial variant may be less aggressive than are the more common bony and deep soft tissue counterparts with an apparently favorable outcome. A retrospective review of patients with cutaneous or subcutaneous ES was conducted to analyze outcome and patterns of failure. Methods and Materials: Between July 1985 and March 1997, 14 patients with cutaneous or subcutaneous ES were treated at St. Jude Children's Research Hospital. The median age at presentation was 16 years (range 7-21 years). Anatomic locations included trunk and pelvis (7), upper or lower extremity (4), and head and neck (3). The median size of the lesion was 3 cm (range, 1-12 cm). Thirteen had definitive surgical resections, and one had biopsy of the mass at the time of referral. They ...

2000-01-15

247

Use of natural gas on heavy duty vehicles in Brazil: experience, current scene and barriers that still persist; Utilizacao do gas natural em veiculos pesados no Brasil: experiencia, cenario atual e barreiras que ainda persistem  

Energy Technology Data Exchange (ETDEWEB)

In the 80's, because of the oil crisis, the Natural Gas (NG) appeared as a fuel with a great potential for Diesel replacement in Heavy Duty Vehicles. At that time, PETROBRAS with other companies have developed partial conversion technologies from Diesel to NG, known as 'Dual Fuel'. Engine dynamometer and vehicle bus tests have been developed to verify its technical and economical viability. Because of several factors, the Dual Fuel Program did not advance and the experience was interrupted. At the same time, other experiences using NG Otto Cycle bus engines, manufactured in Brazil, have been conducted, mainly at Sao Paulo, nevertheless, without expansion. Currently, factors as increase of the NG converted light vehicles fleet; the NG excess in the National Market, which has contributed to the NG distribution net expansion; the Environmental Legislature in vigor, that continuously determine lower emission limits; the government interest in increasing the NG ...

2004-07-01

248

The biofuels excellence network; Rede de excelencia em biocombustiveis  

Energy Technology Data Exchange (ETDEWEB)

The organization of the Biofuels Excellence Network, inside PROMINP - the Program of Mobilization of the National Industry of Oil and Natural Gas, has the objective of improving the actions of technical innovation and management in the chain of Oil, Gas Natural and Biofuels, through the optimized use of physical, financial, technological resources, of information and staff, with maximum qualification in areas of the human knowledge, whose purpose is to make decisions on specific problems of improvement of processes and/or products, besides promoting actions for the development and reinforcement of the markets of ethanol and biodiesel. The organization of the Biofuels Excellence Network became necessary, in order to enable Brazil to reach vanguard standards in biofuels (ethanol and biodiesel) in a sustainable, competitive and environmentally responsible way. Among the main reasons for the creation of the Biofuels Excellence Network are: to speed up the acquisition of knowledge and ...

2008-07-01

249

Synchrotron Self-Compton Analysis of TeV X-ray Selected BL Lacertae Objects  

CERN Document Server

We introduce a methodology for analysis of multiwavelength data from X-ray selected BL Lac (XBL) objects detected in the TeV regime. By assuming that the radio--through--X-ray flux from XBLs is nonthermal synchrotron radiation emitted by isotropically-distributed electrons in the randomly oriented magnetic field of a relativistic blazar jet, we obtain the electron spectrum. This spectrum is then used to deduce the synchrotron self-Compton (SSC) spectrum as a function of the Doppler factor, magnetic field, and variability timescale. The variability timescale is used to infer the comoving blob radius from light travel-time arguments, leaving only two parameters. With this approach, we accurately simulate the synchrotron and SSC spectrum of flaring XBLs in the Thomson through Klein-Nishina regimes. Photoabsorption by interactions with internal jet radiation and the intergalactic background light (IBL) is included. Doppler factors, magnetic fields, and absolute jet powers are obtained by ...

2008-01-01

250

Separation of the components of the binary mixture ethanol-water by steam flux in solid phase column; Separacao dos componentes da mistura binaria etanol-agua por passagem do vapor em coluna de fase solida  

Energy Technology Data Exchange (ETDEWEB)

This paper deals with the energy required to separate ethanol from an aqueous solution in a distillation column containing a solid phase. The solid phases evaluated consisted of either an amylatious (ground corn) or a cellulose (sugar cane bagasse) absorber whit particle sizes smaller than 4 mm. The water-retention capacity of each solid phase was measured by passing vapors or ethanol-water mixtures through the solid phase. When starting with initial concentrations bellow the azeotropic point, ethanol concentrations up to 99,5% (on corn) and 97,2% (on sugar cane) were achieved. The water content was evaluated potentiometrically (Karl`Fischer). Regarding the 2-4 mm ground corn solid phase column, the energy consumed was estimated to be reduced by 15,6% and 60% (by weight) ethanol-water mixture respectively. (author) 11 refs., 2 figs., 2 tabs

1987-12-31

251

Ruthenium-106 brachytherapy for uveal melanomas. Preliminary results: a single institutional experience; Braquiterapia com rutenio-106 em melanomas uveais. Resultados preliminares: experiencia uni-instuticional  

Energy Technology Data Exchange (ETDEWEB)

Objective: To analyze the early response of uveal melanomas in patients treated with ruthenium-106 brachytherapy. Materials And Methods: In the period between April 2002 and July 2003, 20 patients diagnosed with uveal melanoma were submitted to ruthenium-106 brachytherapy. The calculated dose delivered at the apex of the tumor ranged between 55 Gy and 100 Gy. Patients with lesions greater than 5 mm were submitted to transpupillary thermotherapy concomitantly with ophthalmic plaque insertion. Results: As regards the lesions site, 75% of the lesions were located in the choroid, 15% in the iris, and the remainder 10% in the ciliary body. In a median 19-month-follow-up, the progression-free survival for brachytherapy was 69%, and 87% for associated brachytherapy and transpupillary thermotherapy. A significant tumor height reduction was observed after treatment. No patient was submitted to enucleation. Conclusion: Our preliminary results show that ruthenium-106 brachytherapy is an ...

2007-03-15

252

Reverse time migration: resolution in cross well seismic surveys; Migracao reversa no tempo: resolucao em levantamentos sismicos interpocos  

Energy Technology Data Exchange (ETDEWEB)

The standards mapping methods are limited by the lack of information between surface measures and wells profiles. The cross well seismic survey has proven being an effective high-resolution method for reservoirs characterization due its high frequency band. In this work, a 2-D finite differences algorithm for numerical cross well seismic simulation was developed, based in the approach of 2nd order for the time derivatives and 4th order for the space derivatives. In relation to the imaging techniques, it was introduced a reverse time migration method based in the solutions of the wave equation in time for cross well seismic data by the method of the finite differences exclusively. The results of reverse time migration has showed that layers with 90 cm thickness for P-waves could be visualized in migrated sections with excellent resolution. The high frequency cross well seismic data combined with reverse time migration have the potential for revealing never seeing reservoir details using ...

2003-07-01

253

Proximal cholangiocarcinoma. Prognostic factor and effectiveness of post operative radiotherapy  

International Nuclear Information System (INIS)

To define the prognostic factors after surgical resection and evaluate the effectiveness of Post Operative Radiotherapy (PORT) in cases with cholangiocarcinoma, 44 cases with proximal cholangiocarcinoma were examined. The mean observation period was 20.6 months, and the survival rates 1, 3 and 5 years after the resection were 79.9%, 59.8% and 39.3%, respectively. Univariate analysis revealed that the presence of lymph node metastasis and absence of PORT were significant poor prognostic factors. Multivariate analysis revealed that the absence of PORT was a significant poor prognostic factor. The survival rates for 1 and 3 years after the resection were 80.0% and 40.0% in the curable A/B and PORT (-) group, and 100% and 53.3% in curable C and PORT (+) group. There were no local reccurences in the pathologically classified hm2 and em2 patients who underwent PORT. Even when the surgical margin is positive for the carcinoma pathologically, it is possible to avoid local ...

2000-10-01

254

Piperidine adsorption on two different silver electrodes: A combined surface enhanced Raman spectroscopy and density functional theory study  

Energy Technology Data Exchange (ETDEWEB)

The surface enhanced Raman scattering (SERS) spectra of piperidine in silver colloid solution, on roughened silver electrode and on roughened silver electrode modified with silver nanoparticles were studied, and the high-quality SERS spectra of piperidine on roughened silver electrode modified with silver nanoparticles were obtained for the first time. Surface selection rules derived from the EM enhancement model were employed to deduce piperidine orientations on the different surfaces. On the basis of this, two models of piperidine adsorbed on the surface of the silver nanoparticles were built, and DFT-B3PW91/LanL2dz was applied to calculate the Raman frequencies. It proves that, at higher potential values, the piperidine is perpendicularly standing on the roughened silver electrode surface though its lone-electron pair, but in silver colloid solution and on the silver nanoparticles modified silver electrode the piperidine molecular lies flat on the silver ...

2007-10-15

255

Performance evaluation of the conventional Brazilian industries radiation protection in the small industrial gauges and industrial radiography areas; Sistema de avaliacao de desempenho em radioprotecao das industrias convencionais brasileiras nas areas de medidores nucleares e radiografia industrial  

Energy Technology Data Exchange (ETDEWEB)

This works evaluates by punctuation the performance in conventional Brazilian industries radiation protection area which make use of small industrial gauges and industrial radiography. It proposes, procedures for industry self-evaluation, besides a new radiation protection plans pattern for the small industrial gauges area. The data source where inspection reports of Dosimetry Radiation Protection Institute/Nuclear Energy Commission conventional Brazilian industries' radiation protection plans, beyond visitation to the inspection place. The performance evaluation has been realized both in the administrative and operational aspects of the industries. About of 60% of the industries have a satisfactory register control which does not happen to the operational control. The performance evaluation advantage is that industries may self-evaluate, foreseeing Dosimetry Radiation Protection Institute's regulation inspections, correcting its irregularities, automatically ...

1999-08-01

256

Partial Isometries of a Sub-Riemannian Manifold  

CERN Document Server

In this paper, we obtain the following generalisation of isometric $C^1$-immersion theorem of Nash and Kuiper. Let $M$ be a smooth manifold of dimension $m$ and $H$ a rank $k$ subbundle of the tangent bundle $TM$ with a Riemannian metric $g_H$. Then the pair $(H,g_H)$ defines a sub-Riemannian structure on $M$. We call a $C^1$-map $f:(M,H,g_H)\\to (N,h)$ into a Riemannian manifold $(N,h)$ a {\\em partial isometry} if the derivative map $df$ restricted to $H$ is isometric; in other words, $f^*h|_H=g_H$. The main result states that if $\\dim N>k$ then a smooth $H$-immersion $f_0:M\\to N$ satisfying $f^*h|_H

2010-01-01

257

Monitoring the Effect of Longwall Mining on Agricultural Environments - Interim Report  

Energy Technology Data Exchange (ETDEWEB)

The project was designed to quantify the impacts of longwall mine subsidence (LWMS) on the production and quality of agricultural vegetated environments. This project utilised a variety of traditional ground based sampling techniques including biomass harvests and estimates, leaf area index (LAI), pasture height, species composition and soil sampling along with proximal sensor data capture using a Crop Circle{trademark} and an EM38. Satellite imagery was collected using the Quickbird satellite and the high resolution imagery was used to monitor large areas of LWMS affected areas and adjacent un-mined land. Two landscapes were investigated using a whole of mine site technique including remote sensing, ground survey and traditional agricultural monitoring methods. The landscapes were at the Kestrel site in Emerald, QLD including a forage sorghum and an improved pasture and at Beltana in the Hunter Valley, NSW including an irrigated lucerne pasture and an unimproved ...

2009-06-15

258

Models comparative study for heat storage in fixed beds; Estudo comparativo de modelos para armazenamento de calor em leitos fixos  

Energy Technology Data Exchange (ETDEWEB)

This work presents comparative results of a numerical investigation of four possible models for the prediction of thermal performance of fixed bed storage units and their thermal design. These models includes Schumann's model, the radial dispersion model, a model that include both axial heat conduction in the fluid phase and admits thermal gradient in the solids particles and finally a two dimensional single phase model. For each of these models a computer code was written and tested to evaluate the computing time of same data and analyze any other computational problems. The tests of thermal performance included particle size, porosity, particle material, flow rate, inlet temperature and heat losses form tank walls and extremities. Dynamics behaviour of the storage units due to transient variation in either flow rate or inlet temperature was also investigated. The results presented include temperature gradients, pressure drop and heat storage. The results obtained are very ...

1991-07-01

259

Measurement-while-drilling (MWD) development for air drilling  

Energy Technology Data Exchange (ETDEWEB)

The objective of this program is to tool-harden and make commercially available an existing wireless MWD tool to reliably operate in an air, air-mist, or air-foam environment during Appalachian Basin oil and gas directional drilling operations in conjunction with downhole motors and/or (other) bottom-hole assemblies. The application of this technology is required for drilling high angle (holes) and horizontal well drilling in low-pressure, water sensitive, tight gas formations that require air, air-mist, and foam drilling fluids. The basic approach to accomplishing this objective was to modify GEC's existing electromagnetic (e-m) CABLELESS''{trademark} MWD tool to improve its reliability in air drilling by increasing its tolerance to higher vibration and shock levels (hardening). Another important aim of the program is to provide for continuing availability of the resultant tool for use on DOE-sponsored, and other, air-drilling programs.

1992-01-01

260

Material and process improvements in condenser tubing  

Energy Technology Data Exchange (ETDEWEB)

The reliability of the surface condenser is a key factor in plant performance level and maintenance cost optimization. This is especially the case for thermal nuclear plants where condenser raw wa-ter ingress can introduce contamination into the chemically-controlled, steam/water loop potentially causing damage to sensitive equipment. Two important parameters must be taken into account when attempting to optimize the quality and the reliability of condenser tubing. They include selecting the appropriate material according to the cooling water corrosion level present. A second and equally important parameter is the manufac-turing of the tubing product itself. This paper will identify methods to optimize manufacturing processes and improve tubing quality, according to VALTIMET's 30 years of condenser welded tubing production experience. Those methods complete the core manufacturing process (forming and welding), through improvement of the metallurgical homogeneity (Roll Sink ...

2010-07-01

261

Magnetic moment measurements of gadolinium, holmium and ytterbium tartrate trihydrate crystals  

British Library Electronic Table of Contents (United Kingdom)

Magnetic moment and susceptibility of single crystals of rare earth tartrates of the type R(C4H4O6)(C4H5O6)3H2O (where R = Gd, Ho, and Yb), using a vibration sample magnetometer are reported. The experimental values of molar susceptibilities for Gd(C4H4O6)(C4H5O6)3H2O, Ho(C4H4O6)(C4H5O6)3H2O, and Yb(C4H4O6)(C4H5O6)3H2O are 2.58x10-2, 4.66x10-2, and 8.03x10-3 (in cgs em units), respectively. The calculated effective magnetic moments are in good agreement with the theoretical predictions on rare earth ions.

2008-01-01

262

Generalized Collective Inference with Symmetric Clique Potentials  

CERN Document Server

Collective graphical models exploit inter-instance associative dependence to output more accurate labelings. However existing models support very limited kind of associativity which restricts accuracy gains. This paper makes two major contributions. First, we propose a general collective inference framework that biases data instances to agree on a set of {\\em properties} of their labelings. Agreement is encouraged through symmetric clique potentials. We show that rich properties leads to bigger gains, and present a systematic inference procedure for a large class of such properties. The procedure performs message passing on the cluster graph, where property-aware messages are computed with cluster specific algorithms. This provides an inference-only solution for domain adaptation. Our experiments on bibliographic information extraction illustrate significant test error reduction over unseen domains. Our second major contribution consists of algorithms for ...

2009-01-01

263

Facial osteomyelitis as complication of chronic sinusitis in hemophiliac-AIDS patients - scintigraphic evaluation with technetium-99m-MDP and Gallium-67; Osteomielitis da face como complicacao de sinusite cronica em hemofilicos aideticos - avaliacao cintilografica com {sup 99m} Tc-MDP e {sup 67} Ga  

Energy Technology Data Exchange (ETDEWEB)

In the paper six cases of facial osteomyelitis as a complication of chronic sinusitis in hemophiliac-AIDS patients are reported. Osteomyelitis was suggested by an increasing of erythrocyte sedimentation rate. The diagnosis was confirmed by a positive {sup 99m} Tc MDP scintigraphy. The patients were submitted to clinical treatment. The erythrocyte sedimentation rate and 67-gallium citrate scans were used in the follow-up of the therapy. Three patients had negative gallium after three weeks of organism-specific antibiotic therapy; in two patients the gallium scintigraphy remained positive. One patient did not undergo the radionuclide scan for this clinical conditions. These results suggest that MDP scans showed higher sensitivity and specificity in detection of bone disease in chronic sinusitis. Gallium scans appeared to be valuable tool in the follow-up of the infection. There are no reports in the literature of osteomyelitis as a complication of chronic sinusitis in AIDS patient. ...

1997-01-01

264

Exemplification of the Game Theory application in auctions of exploratory blocks; Um exemplo de aplicacao de Teoria dos Jogos em leiloes de blocos exploratorios  

Energy Technology Data Exchange (ETDEWEB)

This article describes a methodology to determine the best strategy in an open bid, where oil and gas fields are the targets for exploration. Based upon the previous bid rounds for a given specific area - the Campos Basin, for that matter -, the data were statistically treated to fit a probability density function, modelling the value of bids offered by the competing companies. By means of techniques and concepts pertaining to Game Theory a balance matrix was built for values of bids made by companies as a function of the company alone in assumed bid rounds. At the end of each british auction, participants of this simultaneous game, using the rationality principle, aimed at winning the tender on the oil field aimed for, through the use of better answers with respect to its rival competitor. The game goal was maximize return on investment purchase in the decisions of lease blocks purchases in the auctions, or to try minimize its opponents gains. Proceeding with the work, this time, ...

2003-07-01

265

Evaluation of the increase of superficial dose due to thermoplastic immobilizing in radiotherapy; Avaliacao dos efeitos de superficializacao de dose por imobilizadores termoplasticos em radioterapia  

Energy Technology Data Exchange (ETDEWEB)

Perforated thermoplastic masks are used to provide patients immobilization. This procedure inserts a material in the path of the radiation beam, that attenuates and modifies the beam fluence and flatness. The present study evaluates the increase in skin dose as a result of using thermoplastic masks. Relative doses were measured on the surface of a solid water phantom, in the presence and absence of masks. These masks were stretched according to deformation patterns observed in clinical routine. The measurements were obtained with a plane-parallel chamber (Markus type 23343) and radiochromic film (EBT Gafchromic) for 6MV X-rays from a linear accelerator, and for a radiation beam from a cobalt therapy unit. The results showed that thermoplastic masks, whose thickness varied between 2 and 3 mm, increased the dose on the surface by a factor of 3. Due to the variations in the skin dose distribution, clinical procedures were suggested to minimize radiobiological damages in subcutaneous ...

2010-07-01

266

Evaluation of specific consumption from the use of chicken oil biodiesel in one cylinder generator set; Avaliacao do consumo especifico a partir da utilizacao de biodiesel de oleo de frango em um grupo-gerador monocilindrico  

Energy Technology Data Exchange (ETDEWEB)

Biodiesel can be produced from numerous materials, including by-products of animal chain. In this scenario, the chicken's oil, that is located and an environment not explored for biodiesel production, can be a good alternative in South and Southeast Brazilian Region, where they are slaughtered around 9.100.000 chickens per day. In order to determine the specific consumption from a generator set with single cylinder 6.6 kW of power and generation capacity of 5 kW, using chicken oil biodiesel (B-100), were performed the bench test using a auxiliary tank, precision scale and an energy analyzer. Were conducted four treatments (25%, 50%, 75% and 100% of generating capacity). The worst SC was the engine at 25% of generation capacity (1.5 kW) and better with 75% of maximum load (3.75 kW) with a mean of 479.34 g kWh{sup -1}. By Turkey's test ant 5% probability there was a significant difference only for the first treatment. (author)

2010-07-01

267

Evaluation of red mud as pozzolanic material in replacement of cement for production of mortars; Avaliacao da lama vermelha como material pozolanico em substituicao ao cimento para producao de argamassas  

Energy Technology Data Exchange (ETDEWEB)

Red mud is a by-product of the alkaline extraction of aluminum from the bauxite and represents a renewed environmental problem due the significant annual throughput by the plants. In the present work, the pozzolanic properties of Brazilian red mud fired at 600, 700, 800 and 900 deg C were investigated by monitoring lime consumption using DTA analysis and Brazilian standard methodology NBR 5772 (1992). Products and kinetics of hydration were determined in cement pastes produced with 5 and 15% red mud using x-ray diffraction and DTA analysis. Compressive strength and capillary absorption tests were realized on mortars constituted by 5, 10 and 15% red mud in replacement of cement. When calcined at 600 deg C, the red mud develops good pozzolanic properties, and the compressive strength of mortars produced with this waste meet values in accordance with regulatory standard. These results shown than red mud can be used, in partial replacement of cement, as new construction material to produce ...

2010-07-01

268

Effects of morpho dynamics in shallow waters over pipeline facilities; Efeitos da morfodinamica em aguas rasas sobre instalacoes de dutos  

Energy Technology Data Exchange (ETDEWEB)

The success in developing of the oil industry operating in offshore-onshore terminals, connected by pipelines with the facilities of the coastal zone, can be attributed partially to the beach morpho dynamic monitoring. This study represents a solution to the concerns of the technical operations in coastal zones because it minimizes the impact of the petroleum production and it assures the environmental protection associated to the risks of the pipelines breaking. This impact type results mainly of the vertical and horizontal displacements of the beach, from the coastal dunes to the shore face. The mobility of the profile is associated to the magnitude of the sedimentary processes, which reproduce naturally or not, in scale of time that can vary among few days, years or decades. For the monitoring and interpretation of the beach profile mobility the following methods are recommended: calculation of the closure depth with base in the wave data; bathymetric survey with sled; calculation ...

2003-07-01

269

Determination of the initial energy in computerized tomography with proton beams; Determinacao da energia inicial em tomografia computadorizada com feixe de protons  

Energy Technology Data Exchange (ETDEWEB)

In earliest works devoted to proton computed tomography it was shown that the advantage of pCT image reconstruction appears when the energy is close to the Bragg peak region, since the proton passes the object. This effect provided by the Bragg peak makes the computerized tomography with protons possible. However, when decreasing the initial proton energy, with the increase of the irradiation dose, there are two effects that work simultaneously in opposite ways. First, the energy loss of a proton in an object becomes bigger at small initial energy. At the same time decreasing of the proton energy results in the increase of the energy straggling, requiring a larger number of protons. In this work the radiation dose dependence on the proton initial energy was studied using analytical formulas and computer simulations. The investigation determined that the radiation dose practically does not depend on the initial energy, except in the energy region very close to the minimum energy ...

2007-07-01

270

Core Heat Transfer Model Validation of the TASS/SMR-S Code using the Bennett's Test  

International Nuclear Information System (INIS)

The SMART (System-integrated Modular Advanced ReacTor) which is a 330 MWt advanced integral PWR was developed by the KAERI (Korea Atomic Energy Institute) for electricity generation and seawater desalination. A thermal hydraulic evaluation and analysis of the SMART is performed by the TASS /SMR-S (Transient And Setpoint Simulation/System integrated Modular Reactor-Safety). The TASS/SMR-S code has various models reflecting the design features of the SMART such as the drift flux model, the core models (core power and core heat transfer model), the component models, and the specific models. One of the core models is the core heat transfer model. The role of this model is to calculate the heat flux and radial temperature profiles at a fuel rod surface using the relevant heat transfer correlations for all of the heat transfer modes. Also it is modeled to meet the requirements of the 10 CFR 50 appendix K EM model for the CHF (Critical Heat Flux) and post CHF conditions. ...

2010-10-01

271

Computing Good Nash Equilibria in Graphical Games  

CERN Document Server

This paper addresses the problem of fair equilibrium selection in graphical games. Our approach is based on the data structure called the {\\em best response policy}, which was proposed by Kearns et al. \\cite{kls} as a way to represent all Nash equilibria of a graphical game. In \\cite{egg}, it was shown that the best response policy has polynomial size as long as the underlying graph is a path. In this paper, we show that if the underlying graph is a bounded-degree tree and the best response policy has polynomial size then there is an efficient algorithm which constructs a Nash equilibrium that guarantees certain payoffs to all participants. Another attractive solution concept is a Nash equilibrium that maximizes the social welfare. We show that, while exactly computing the latter is infeasible (we prove that solving this problem may involve algebraic numbers of an arbitrarily high degree), there exists an FPTAS for finding such an equilibrium as long as the best ...

2007-01-01

272

Cogeneration in air separation cryogenic plants; Cogeracao em plantas criogenicas de separacao de ar  

Energy Technology Data Exchange (ETDEWEB)

A thermal and economic study, carried on by using the first and second law of thermodynamics concepts demonstrated the economic feasibility of the cogeneration system, and proposed modifications to be done in the studied cryogenic plant, a typical T-240 NA MPL3 plant. The thermodynamic analysis showed that the second law efficiency of the processes could be improved, together with a 12% electric energy consumption reduction. Four cogeneration schemes were analyzed with both the first and second laws of thermodynamics and, then, the economic analysis was performed. Rankine, Brayton, Otto and Combined gas-steam basic cycles were used in this analysis.The combined gas-steam cycle was shown to be more economically feasible than others. Thermal and electric loads were well balanced, resulting in a higher second law efficiency. Although the initial investment for the modification was higher, the savings resulted to be higher, turning into a higher rate of return of the investment. (author)

2000-07-01

273

Cavity detection based on EM migration of TEM data; TEM ho data no denji migration ni yoru kudo kenshutsu no kokoromi  

Energy Technology Data Exchange (ETDEWEB)

With an objective to discuss applicability of resistivity imaging using electromagnetic migration to detection of underground cavity, an applicability test was carried out on calculation of a numerical model and measurement data. By using the numerical model, a calculation was performed on a hypothetical case that a cubic cavity with sides each at 40 m exists in a homogenous medium of 200 ohm-m, with the cavity top located 20 m below the ground surface. As a result, it was possible to structure in a very short calculation time an image of the cavity which cannot be identified by one-dimensional inverse analysis. In the case of this cavity, a center of the image was structured on its lower face. It was shown that a location to indicate the image must be changed according to difference in the measurement locations. In a test on data measured in an underground cavity in the city of Utsunomiya, Tochigi Prefecture, it was found that the result may vary largely depending on structure of the ...

1997-05-27

274

Bioremediation process in impacted area of petroleum activities; Processos de biorremediacao em areas influenciadas por atividades petroliferas  

Energy Technology Data Exchange (ETDEWEB)

The present work's objective is to test sampling methodologies applied on the bioremediation processes in situ, involving the establishment of sample replicates, specific laboratory procedures and its results, inedited on the referred technique. Agricultural fertilizers were used, NPK and OSMOCOTE, as biostimulants on mangroves substrates affected by petroleum activities. The tested methodology used on the experiment was based on the monitoring of this technology in aquarium with water from Sao Paulo's river and sediment contaminated by oil, realized in three steps (first pre-test, second pre-test and third pre-test) that happened between the months of August and November of 2007. The physical-chemical parameters were measured with portable devices carefully calibrated and the oil analyzed with gas chromatography. The saturated hydrocarbons (n-alkenes) had an increase on the concentrations for some aquariums and these found results do not permit to confirm if the ...

2008-07-01

275

An efficient method for 3-D pre stack migration in time reverse-time depth by using finite difference method; Um metodo eficiente para migracao pre-empilhamento 3-D em profundidade reversa no tempo pelo metodo das diferencas finitas  

Energy Technology Data Exchange (ETDEWEB)

Much of the current technology on 3D-prestack depth migration is based on the Kirchhoff method and the traveltime information needed for this purpose is obtained by the ray-theory approximation. The main motivation driving these options is to reduce computations but it can also have an adverse effect on the quality of results. Experience with real data indicates that the corresponding poststack data migrated by the reverse-time method often yields superior results. Considerable computational efficiency can be obtained by employing nonuniform coarse grid spacing during the reverse-time migration. We followed this strategy for developing a parallel scheme for doing 3D- prestack depth migration. However, we worked only on a small subset of shot gathers whose determined by the Quasi-Monte Carlo method. The results were indistinguishable from those obtained by using a much larger population of uniformly spaced shot gathers. We present examples of migration of 3-D data. (author)

1997-07-01

276

A single sorbent for tetracycline enrichment and subsequent solid-matrix time-resolved luminescence  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study was to search for a sorbent that could act as an extraction phase and as a support for solid-matrix time-resolved luminescence (SMTRL). Four potential sorbents were investigated for this purpose using tetracycline (TC) as a model analyte. Sorbents prepared from C18 silica gel or calcium cross-linked pectin gel were able to extract TC from dilute solutions. Europium(III)-TC complex adsorbed on the surface of C18 generated the most intense TRL signal when measured at {lambda}{sub ex} = 388 nm and {lambda}{sub em} = 615 nm. This method achieved a 1 ng/ml limit of detection (LOD) with a 100 {mu}l sample solution in a repeated spotting mode. Hyphenation of sorbent extraction and SMTRL was demonstrated using C18. This method is suitable for screening of TC in foods or aqueous solutions and can be extended to other luminescent lanthanide-chelating analytes in physiological or environmental samples.

2005-01-10

277

Study of the inorganic constituents in different species of Casearia medicinal plant collected in distinct regions of the Atlantic Forest, SP State, Brazil; Estudo sobre os constituintes inorganicos presentes em diferentes especies da planta medicinal do genero Casearia coletadas em regioes distintas da Mata Atlantica, SP  

Energy Technology Data Exchange (ETDEWEB)

The use of medicinal plants in the treatment of diseases has increased significantly in the last years, as has research concerning chemical characterization of these plants. In this study, inorganic constituents were determined in leaves and in extracts from three medicinal plant species of the Casearia genus (C. sylvestris, C. decandra and C. obliqua) collected in distinct regions of the Atlantic Forest, SP. The elemental compositions of the soils in which these plants were grown were also determined. Traditionally, these plants are used due to their antiinflammatory, antiacid, antiseptic and cicatrizing properties. The antiulcer and the antitumor activities of the Casearia genus and its capacity to neutralize snake and bee venoms, have also been scientifically confirmed. The analytical methodology used was neutron activation analysis. Long and short irradiation periods of the samples and the standards were carried out at IPEN's IEA-R1 nuclear research reactor. In the leaf K ...

2006-07-01

278

Proposal of procedures to prevent errors in radiotherapy based in learned lessons of accidental expositions; Proposta de procedimentos para evitar erros em radioterapia baseados em licoes aprendidas de exposicoes acidentais  

Energy Technology Data Exchange (ETDEWEB)

In order to consider some procedures to prevent errors in radiotherapy based in learned lessons of accidental expositions and in accordance with information contained in international reports elaborated by International Atomic Energy Agency (IAEA) and of the data base availability by the European group Radiation Oncology Safety Information System (ROSIS) on the events, a research of the occurred errors was performed. For the evaluation of the incidents a data base based in the ROSIS and added plus a parameter was created 'type of error'. All the stored data make possible the evaluation of the 839 incidents in terms of frequency of the type of error, the process of detention, the number of reached patients and the degree of severity. Of the 50 types of found errors, the type of error more frequently was 'incorrect treatment coordinate', confirmed with the data of literature and representing 28,96 por cent of the total of the incidents. The results ...

2007-07-01

279

MENDING THE IN SITU MANIPULATION BARRIER  

Energy Technology Data Exchange (ETDEWEB)

In early 2004, the U.S. Department of Energy (DOE) Richland and Fluor Hanford requested technical assistance from the DOE Headquarters EM-23 Technical Assistance Program to provide a team of technical experts to develop recommendations for mending the In Situ Redox Manipulation (ISRM) Barrier in the 100-D Area of the Hanford Site in Washington State. To accommodate this request, EM-23 provided support to convene a group of technical experts from industry, a national laboratory, and a DOE site to participate in a 2 1/2-day workshop with the objective of identifying and recommending options to enhance the performance of the 100-D Area reactive barrier and of a planned extension to the northeast. This report provides written documentation of the team's findings and recommendations. In 1995, a plume of dissolved hexavalent chromium [Cr(VI)], which resulted from operation of the D/DR Reactors at the Hanford site, was discovered along the ...

2006-02-06

280

A multi-disciplinary study investigating radiotherapy in Ewing's sarcoma - a final report of POG 8346  

International Nuclear Information System (INIS)

Purpose: To determine if involved field radiation (IF) is equivalent to standard whole bone radiation (SF) in local tumor control; to establish patterns of failure following treatment; and to determine response, event free (EFS) and overall survival rates from multi-disciplinary therapy in Ewing's Sarcoma (ES). Materials and Methods: Between 1983 and 1988, 184 children with ES were enrolled onto POG 8346. 178 (97%) met eligibility criteria; 6 had non-ES pathology. Induction treatment of Cyclophosphamide/Adriamycin (C/A) x 12 weeks was followed by local treatment either surgery or radiation therapy (XRT) and C/A, Dactinomycin and Vincristine for 50 weeks. Resection was advised for patients with small primary tumors if accomplished without functional loss. 40 patients were randomized to receive SF, whole bone XRT to 39.6 Gy plus a 16.2 Gy boost (total 55.8 Gy) or IF to 55.8 Gy while 84 were assigned to IF XRT. Results: Of 179 eligible patients, 141 (79%) had ...

281

Dosimetry for Total Skin Electron Beam Therapy in Skin Cancer  

International Nuclear Information System (INIS)

Increasing frequency of skin cancer, mycosis fungoides, Kaposi sarcoma etc, it need to treatment dose planning for total skin electron beam (TSEB) therapy. Appropriate treatment planning for TSEB therapy is needed to give homogeneous dose distribution throughout the entire skin surface. The energy of 6 MeV electron from the 18 MeV medical linear accelerator was adapted for superficial total skin electron beam therapy. The energy of the electron beam was reduced to 4.2 MeV by a 0.5cmx90cmx180cm acryl screen placed in a feet front of the patient. Six dual field beam was adapted for total skin irradiation to encompass the entire body surface from head to toe simultaneously. The patients were treated behind the acryl screen plate acted as a beam scatterer and contained a parallel-plate shallow ion chamber for dosimetry and beam monitoring. During treatment, the patient was placed in six different positions due to be homogeneous dose distribution for whole skin around ...

1992-06-01

282

Comparison of internal emitter radiobiology in animals and humans  

Energy Technology Data Exchange (ETDEWEB)

Investigations of radionuclide metabolism and effects in various mammalian species revealed important similarities between animals and humans and between some animal species. These include skeletal deposition of radium and radiostrontium in bone volume; deposition on bone surfaces of plutonium and other actinides; liver deposition of actinides; induction of skeletal or liver malignancies by these radionuclides; induction of tooth and jaw abnormalities; mammary cancer induction by radium in humans and in the beagle; depression of circulating cells in blood; and induction of bone fractures. There are also inter-species differences that may not have been noted if multiple species (including humans) had not been studied. Some of these are more rapid excretion of radium in humans compared with most other mammals; induction by radium of eye melanomas in animals but not humans; rapid loss of deposited plutonium from liver in many species of mice and rats but not in humans and dog; substantial ...

1997-01-01

283

Trap-nests used by Centris (Heterocentris) terminata Smith (Hymenoptera: Apidae, Centridini) at secondary Atlantic Forest fragments, in Salvador, Bahia State; Ninhos de Centris (Heterocentris) terminata Smith (Hymenoptera: Apidae, Centridini) em fragmentos de Mata Atlantica secundaria, Salvador, BA  

Energy Technology Data Exchange (ETDEWEB)

Ninety-five nests of Centris (Heterocentris) terminata Smith were collected in trap nests, during November/2001 and January/2003, at two fragments (PZGV e CFO-UFBA) of secondary Atlantic Forest, in Salvador, Bahia State (13 deg 01' W and 38 deg 30' S). The highest nest frequencies occurred from December to February (summer), with no nests foundations from August to October (winter - early spring). Two-hundred eight adults emerged from 347 brood cells, being 164 males and 116 females (1: 0.42). During the study period sex ratio was male biased ({chi}{sup 2} = 9.342; gl = 10; P < 0.05). C. terminata nested in holes with diameters 6, 8, 10 mm, but 84,2% were constructed in 8 and 10 mm. nests had one to seven cells arranged in a linear series with the cell's partitions built with a mixture of sand and resin or oil. Male is significantly smaller than female, which emerges from the first cells constructed. Immature mortality occurred in 14.1% of brood cells ...

2008-05-15

284

The interaction of /sup 125/I-insulin with cultured 3T3-L1 adipocytes: quantitative analysis by the hypothetical grain method  

Energy Technology Data Exchange (ETDEWEB)

The murine 3T3-L1 fibroblast under appropriate incubation conditions differentiates into an adipocyte phenotype. This 3T3-L1 adipocyte exhibits many of the morphologic, biochemical, and insulin-responsive features of the normal rodent adipocyte. Using quantitative electron microscopic (EM) autoradiography we find that, when /sup 125/I-insulin is incubated with 3T3-L1 adipocytes, the ligand at early times of incubation localizes to the plasma membrane of the cell preferentially to microvilli and coated pits. When the incubation is continued at 37 degrees C, /sup 125/I-insulin is internalized by the cells and preferential binding to the villous surface is lost. With the internalization of the ligand, two intracellular structures become labeled, as determined by the method of hypothetical grain analysis. These include large clear, presumably endocytotic, vesicles and multivesicular bodies. Over the first hour of incubation the labeling of these structures increases in ...

1983-07-01

285

Soybean biodiesel consumption in agricultural tractor submitted the two forces in the traction bar; Consumo de biodiesel de soja em trator agricola submetido a duas forcas na barra de tracao  

Energy Technology Data Exchange (ETDEWEB)

Due to the great development occurred in the world after the Second World War and the establishment of patterns of increasingly intense, the energy demand amounted to the point, putting at risk the non-renewable energy sources such as oil, coal minerals, among others, with growing interest in renewable energies, among which the biodiesel has been detached. In this sense, the present work had for objective to evaluate the fuel consumption of a tractor Valtra BM100 4x2 TDA, running with ethyl biodiesel from soybean filtered in seven mixture proportions mixed with the diesel, subject to two forces in the traction bar. The work was conducted in the Department of Rural Engineering of the Paulista State University (UNESP), Jaboticabal Campus, in an entirely randomized designed, in a factorial diagram 2 x 7, with three repetitions. The treatments were a combination for two forces in the traction bar (10 and 22 kN) and seven mixture proportions (B{sub 0}, B{sub 5}, B{sub 1}5, B{sub 2}5, B{sub ...

2009-07-01

286

Seasonal variations in photosynthetic response of algae epiphytic on Myriophyllum spicatum L  

Energy Technology Data Exchange (ETDEWEB)

The photosynthetic response to light of epiphytic algae from Lake Wingra, Wisconsin was determined monthly during the 1978 and 1979 growing seasons.A /sup 14/C technique was developed for measurement of photosynthesis of the intact epiphyte community which was then removed by shaking. The photosynthetic rate at low light, ..cap alpha.., varied from 5.56 to 18.26 ..mu..g C (mg Chl a)/sup -1/ h/sup -1/ (..mu..Em/sup -2/s/sup -1/)/sup -1/ while P/sup B//sub max/, the photosynthetic rate at light saturation, ranged from 1.0 to 2.6 mg C (mg Chl a)/sup -1/ h/sup -1/. During 1979, variations in ..cap alpha.. and P/sup B//sub max/ followed the sun-shade model for photosynthetic adaptation: P/sup B//sub max/ was highest in summer and lowest in spring and fall, while ..cap alpha.. followed the opposite pattern. Patterns in ..cap alpha.. and P/sup B//sub max/ for 1978 were less apparent. During 1979, P/sup B//sub max/ was significantly correlated with both temperature and ...

1982-07-01

287

SUPPLEMENTAL COLUMBIA RIVER PROTECTION ACTIVITIES AT THE DEPARTMENT OF ENERGY HANFORD SITE: 2006 TECHNICAL PEER REVIEW  

Energy Technology Data Exchange (ETDEWEB)

Prompted by a $10 million Congressional allocation to identify supplemental actions to protect the Columbia River from groundwater contamination beneath the Hanford Reservation, the U. S. Department of Energy (DOE) Environmental Management (EM) Office of Clean-up Technology identified twenty-three potential technical projects and then down-selected ten of these for further evaluation. An independent expert peer review was conducted for the ten down-selected proposals. The review panel consisted of twenty-three recognized subject matter experts that broadly represented academia, industry, and federal laboratories. Of the initial ten proposals reviewed, one was given unconditional support, six were given conditional support, and three were not supported as proposed. Three additional proposals were then submitted by DOE for review--these proposals were structured, in part, to respond to the initial round of technical peer review comments. Peer reviews of these ...

2006-12-20

288

Real-time neutron radiography; Radiografia com neutrons em tempo-real  

Energy Technology Data Exchange (ETDEWEB)

The main objective of the present thesis was develop and get operational a real-time neutron radiography system, at the IPEN-CNEN/SP. This system is installed inside the shielding of an old facility, designed in 1988, for film radiography, which is installed at the beam-hole 08 of the 5 MW, IEA-R1 Nuclear Research Reactor. The most important modifications at the such facility were the increase of the {gamma}-radiation filter thickness, increase of the inner area of the shielding, design of a neutron collimator and a light tight box. The main characteristics of the neutron beam at the irradiation position are: flux: 1 x 10{sup 6}n/cm{sup 2}s, collimation ratio 70, effective energy 7 meV, diameter 20 cm, neutron/{gamma} ratio {approx} 10{sup 6}n/cm{sup 2}mrem. The real-time images have been obtained by means of an imaging system that consists of a screen scintillator, a light intensifier, a video camera, a digitizing frame grabber and a computer. The device composed by the scintillator ...

2000-07-01

289

Occupational exposure prevention program to oil and gas industry; Antecipacao, reconhecimento, avaliacao e controle dos riscos ambientais em uma planta de petroleo e gas  

Energy Technology Data Exchange (ETDEWEB)

PETROBRAS/TRANSPETRO Pipelines and Terminals have 500 regular employees and 5.064 out sourced workers in its Southeast Division. The out sourced employees work under 125 contracts involving a wide range of activities such as maintenance, pipeline operation, pipeline launching, engineering, administrative and auxiliary services. Among these workers, 1.200 peoples are subjected to occupational exposure, which may be present in the industrial process or in the products transported in our pipelines, e.g. industrial noise, sulfidric gas, toluene, xylene and benzene (recognized as a carcinogen according to ACGIH and Brazilian Ministry of Labour). Our PPRA (acronym in Portuguese for Occupational Exposure Prevention Program) involves the workforce and fosters health by anticipation, recognition, evaluation and control of the situations that may result in injuries. Further actions include the procurement of equipment for detection of these agents not only in the air but also diluted in liquids ...

2005-07-01

290

Luminescent platinum(II) complexes of quinoxaline-2,3-dithiolate  

Energy Technology Data Exchange (ETDEWEB)

The synthesis, characterization, and photophysical properties of several Pt(II) complexes of quinoxaline-2,3-dithiolate (qdt) and 6,7-dimethylquinoxaline-2,3-dithiolate (dmqdt) are described. Specifically, (TBA){sub 2}[Pt(qdt){sub 2}], where TBA = tetra-n-butylammonium, Pt(COD)(qdt), where COD = 1,5-cyclooctadiene, and Pt(phen)(qdt), where phen = 1,10-phenanthroline, and their dmqdt analogs have been prepared and examined with respect to their photophysical properties. Highly structured emission from Pt(COD)(qdt) in frozen glass solution at 77 K has been detected, having a major vibrational progression of 1370 cm{sup {minus}1} corresponding to a C=C stretching frequency of the quinoxalinedithiolate backbone. Solution luminescence from (TBA){sub 2}[Pt(qdt){sub 2}] and Pt(phen)(qdt) has been detected with quantum yields, {Phi}{sub em}, of 10{sup {minus}5} and 10{sup {minus}3}, respectively, although the latter is highly sensitive to solvent effects. The complex ...

1995-04-12

291

Gas Storage Technology Consortium  

Energy Technology Data Exchange (ETDEWEB)

The EMS Energy Institute at The Pennsylvania State University (Penn State) has managed the Gas Storage Technology Consortium (GSTC) since its inception in 2003. The GSTC infrastructure provided a means to accomplish industry-driven research and development designed to enhance the operational flexibility and deliverability of the nation's gas storage system, and provide a cost-effective, safe, and reliable supply of natural gas to meet domestic demand. The GSTC received base funding from the U.S. Department of Energy's (DOE) National Energy Technology Laboratory (NETL) Oil & Natural Gas Supply Program. The GSTC base funds were highly leveraged with industry funding for individual projects. Since its inception, the GSTC has engaged 67 members. The GSTC membership base was diverse, coming from 19 states, the District of Columbia, and Canada. The membership was comprised of natural gas storage field operators, service companies, industry ...

2010-09-30

292

Gamma irradiation in the control of pathogenic bacteria in refrigerated ground chicken meat; Irradiacao gama no controle de bacterias patogenicas em carne de frango refrigerada  

Energy Technology Data Exchange (ETDEWEB)

This work evaluated the effect of gamma radiation on reducing the population of Staphylococcus aureus, Escherichia coli nd Salmonella typhimurium in ground chicken breast stored under refrigeration. The experiment included a control and 4 doses of gamma radiation ( 2.0, 4.0, 6.0 and 8.0 kGy) along with 5 periods of storage under refrigeration ( 1, 7 14, 21 and 28 days). Samples of ground chicken breast were inoculated with Staphylococcus aureus (ATCC 14458), Escherichia coli (ATCC 11105) and Salmonella typhimurium (ATCC 0626), irradiated at temperatures between 4 and 8 deg C and stored under refrigeration (5 deg C) for 28 days. The increased radiation dose and period of storage under refrigeration caused a reduction of Staphylococcus aureus, Escherichia coli and Salmonella typhimurium populations in the ground chicken breast. Mean radiation D values determined for Staphylococcus aureus and Escherichia coli were 0.41 and 0.72 kGy, respectively. Gamma irradiation was an effective ...

2000-09-01

293

Galaxy Group at z=0.3 Associated with the Damped Lyman Alpha System Towards Quasar Q1127-145  

CERN Document Server

We performed a spectroscopic galaxy survey, complete to $m_{F814W}\\leq20.3$ ($L_B>0.15L_B^{\\star}$ at z=0.3), within 100x100'' of the quasar Q1127-145 ($z_{em}=1.18$). The VLT/UVES quasar spectrum contains three $z_{abs}<0.33$ MgII absorption systems. We obtained eight new galaxy redshifts, adding to the four previously known, and galaxy star formation rates (SFRs) and metallicities were computed where possible. A strong MgII system [$W_r(2796)=1.8$A], which is a known damped Ly$\\alpha$ absorber (DLA), had three previously identified galaxies; we found two additional galaxies associated with this system. These five galaxies form a group with diverse properties, such as a luminosity range of $0.04\\leq L_B\\leq0.63 L_B^{\\star}$, an impact parameter range of $17\\leq D \\leq 241$ kpc and velocity dispersion of $\\sigma$=115 km/s. The DLA group galaxy redshifts span beyond the 350 km/s velocity spread of the metallic absorption lines of the DLA itself. The ...

2010-01-01

294

Effects of holmium laser on dental structure in vivo: thermal evaluation and histological analysis on pulpal tissue; Efeitos in vivo do laser de holmio em estrutura dental: monitoracao termica e analise histologica do tecido pulpar  

Energy Technology Data Exchange (ETDEWEB)

Previous in vitro studies have demonstrated that Ho:YLF laser is capable of inducing physical and chemical changes on dental surfaces treated for caries prevention. The temperature in the pulp chamber was in vitro evaluated to as a function of the power and frequency of the laser irradiation. The purpose of this work is to verify the occurrence of pulp inflammation after Ho:YLF laser irradiation using different parameters in rabbits' teeth. The premolars and molars of ten rabbits (NZB) were divided in two groups according to the irradiation energy values of a Ho:YLF laser prototype operating at 2.065{mu}m wave length, frequency of O,5Hz and pulse length of 250{mu}s. An group A teeth were irradiated with using ten pulses of 334mJ/pulse of a Ho:YLF laser prototype operating at O.5Hz, and group B, with 512mJ/pulse. Animals were killed by transcardiac perfusion and the samples were prepared for histopathological analysis. The in vitro temperature monitoring revealed an increase of ...

2001-07-01

295

Determination of volatiles produced during radiation processing in food and medicinal herbs; Determinacao de volateis produzidos durante o processamento por radiacao em ervas alimenticias e medicinais  

Energy Technology Data Exchange (ETDEWEB)

In order to protect food from pathogenic microorganisms as well as to increase its shelf life while keeping sensorial properties (e.g. odor and taste), once the latter are one of the main properties required by spice buyers, it is necessary to analyze volatile formation from irradiation of medicinal and food herbs. The aim of the present study was to analyze volatile formation from Co irradiation of Laurus Cinnamomum, Piper Nigrum, Origanum Vulgare and Myristica Fragans. Possible changes on the odor of these herbs are evaluated by characterizing different radiation doses and effects on sensorial properties in order to allow better application of irradiation technology. l he samples have been irradiated in plastic packages by making use of a {sup 60}Co Gamma irradiator. Irradiation doses of 0, 5, 10, 15, 20 and 25kGy have been tested. For the analysis of the samples, SPME has been applied, while for the analysis of volatile compounds, CG/MS. Spice irradiation has promoted mostly ...

2008-07-01

296

D & D screening risk evaluation guidance  

Energy Technology Data Exchange (ETDEWEB)

The Screening Risk Evaluation (SRE) guidance document is a set of guidelines provided for the uniform implementation of SREs performed on decontamination and decommissioning (D&D) facilities. Although this method has been developed for D&D facilities, it can be used for transition (EM-60) facilities as well. The SRE guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the current risk to human health and the environment, exterior to the building, from ongoing or probable releases within a one-year time period. The Worker Exposure Index (WEI) calculates the current risk to workers, occupants and visitors inside contaminated D&D facilities due to contaminant exposure. The Future Release Index (FRI) calculates the ...

1995-09-01

297

Coilgun Launcher for Nanosatellites  

Energy Technology Data Exchange (ETDEWEB)

Nanosatellite space launches could significantly benefit from an electrically powered launch complex, based on an electromagnetic coil launcher. This paper presents results of studies to estimate the required launcher parameters and some fixed facility issues. This study is based on electromagnetic launch, or electromagnetic gun technology, which is constrained to a coaxial geometry to take advantage of the efficiency of closely-coupled coils. A baseline configuration for analysis considers a payload mass of 10 kg, launch velocity of 6 km/s, a second stage solid booster for orbital insertion, and a payload fraction of about 0.1. The launch facility is envisioned as an inclined track, 1-2 km in length, mounted on a hillside at 25 degrees aimed in the orbital inclination of interest. The launcher energy and power requirements fall in the range of 2000 MJ and 2 MW electric. This energy would be supplied by 400 modules of energy storage and magnetic coils. With a prime power generator of 2 ...

1999-03-23

298

Aquatic macroinvertebrates and water quality of Sandia Canyon, Los Alamos National Laboratory, December 1992--October 1993. Status report  

International Nuclear Information System (INIS)

In the summer of 1990, an accidental spill from the TA-3 Power Plant Environment Tank released more than 3,785 liters of sulfuric acid into upper Sandia Canyon. The Biological Resource Evaluation Team (BRET) of EM-8 at Los Alamos National Laboratory (LANL) has collected aquatic samples from the stream within Sandia Canyon since then. These field studies gather water quality measurements and collect macroinvertebrates from permanent sampling sites. An earlier report by Bennett (1994) discusses previous BRET aquatic studies in Sandia Canyon. This report updates and expands Bennett's initial findings. During 1993, BRET collected water quality data and aquatic macroinvertebrates at five permanent stations within the canyon. The substrates of the upper three stations are largely sands and silts while the substrates of the two lower stations are largely rock and cobbles. The two upstream stations are located near outfalls that discharge industrial and sanitary waste ...

2004-06-01

299

Alternative fuel buses currently in use in China: Life-cycle fossil energy use, GHG emissions and policy recommendations  

International Nuclear Information System (INIS)

The Chinese government has enacted policies to promote alternative vehicle fuels (AVFs) and alternative fuel vehicles (AFVs), including city bus fleets. The life cycle (LC), energy savings (ES) and GHG reduction (GR) profiles of AVFs/AFVs are critical to those policy decisions. The well-to-wheels module of the Tsinghua-CA3EM model is employed to investigate actual performance data. Compared with conventional buses, AFVs offer differences in performance in terms of both ES and GR. Only half of the AFVs analyzed demonstrate dual benefits. However, all non-oil/gas pathways can substitute oil/gas with coal. Current policies seek to promote technology improvements and market creation initiatives within the guiding framework of national-level diversification and district-level uniformity. Combined with their actual LC behavior and in keeping with near- and long-term strategies, integrated policies should seek to (1) apply hybrid electric technology to diesel buses; (2) ...

2010-01-01

300

A comparison of algorithms for inference and learning in probabilistic graphical models.  

Science.gov (United States)

Research into methods for reasoning under uncertainty is currently one of the most exciting areas of artificial intelligence, largely because it has recently become possible to record, store, and process large amounts of data. While impressive achievements have been made in pattern classification problems such as handwritten character recognition, face detection, speaker identification, and prediction of gene function, it is even more exciting that researchers are on the verge of introducing systems that can perform large-scale combinatorial analyses of data, decomposing the data into interacting components. For example, computational methods for automatic scene analysis are now emerging in the computer vision community. These methods decompose an input image into its constituent objects, lighting conditions, motion patterns, etc. Two of the main challenges are finding effective representations and models in specific applications and finding efficient algorithms for inference and ...

2005-09-01

301

In vitro evaluation of herpes simplex virus type 1 thymidine kinase reporter system in dynamic studies of transcriptional gene regulation  

Energy Technology Data Exchange (ETDEWEB)

The herpes simplex virus type 1 thymidine kinase (HSV1-TK) reporter system is being used to directly and indirectly monitor therapeutic gene expression, immune cell trafficking and protein-protein interactions in various living animals. However, the issues of HSV1-TK enzyme stability in living cells and whether this reporter system is optimal for dynamic studies of gene expression events in genetic imaging have not be addressed. The purpose of the present study was to evaluate the application of this reporter system in dynamic studies of transcriptional gene regulation. To achieve this purpose, we established two tetracycline-inducible murine sarcoma cell lines, tetracycline-turn-off HSV1-tk-expressing cell line (NG4TL4/tet-off-HSV1-tk) and tetracycline-turn-off Luc-expressing cell line (NG4TL4/tet-off-Luc), to create an artificially regulated gene expression model in vitro. The dynamic transcriptional events mediating a series of doxycycline (Dox) inductions were ...

2006-07-15

302

Spectroscopic characterization and temporal dynamics of energy transfer process between Tm{sup 3+} -Ho{sup 3+} and Yb{sup 3+} -Tm{sup 3+} ions in LiYF{sub 4} and LiLuF{sub 4} crystals; Caracterizacao espectroscopica e dinamica temporal dos processos de transferencia de energia entre os ions Tm{sup 3+} -Ho{sup 3+} e Yb{sup 3+} -Tm{sup 3+} em cristais de LiYF{sub 4} and LiLuF{sub 4}  

Energy Technology Data Exchange (ETDEWEB)

In this work, we perform spectroscopic studies to characterize the energy transfer processes occurring in rare-earth doped lithium fluoride systems, aiming the optimization of the population inversion of these media. Yb{sup 3+} ion was used in order to probe the electron-phonon coupling in LiYF{sub 4}, LiGdF{sub 4} and LiLuF{sub 4} matrices. In these systems it was obtained the average phononenergy, the vibronic transition probability and Huang-Rhys coupling constant. These parameters are dependent on the crystal host and the LiLuF{sub 4} system presents excluded correlation effects, an electronic repulsion that weakens the vibronic coupling. The Tm:Ho:LiYF{sub 4} system was studied under diode laser pumping at 796 nm, aiming the 2 {mu}m emission optimization. The ideal conditions of concentration and laser power were determined favouring the latter emission. Upconversion processes of two photons were identified besides the energy transfer among ions. The dynamic processes of ...

2001-07-01

303

Size and morphology of heavy-duty vehicle particle emissions; Raskaan ajoneuvokannan hiukkaspaeaestoen koko ja morfologia - HD-PM  

Energy Technology Data Exchange (ETDEWEB)

Formation of particles from heavy duty diesel and CNG vehicles was studied in laboratory conditions. PM, nano and soot mode particle emissions formed from buses of Euro 2-5 -emission levels were studied in relation to age and type approval characteristics of the vehicle. Characteristic particle emission factors from city driving were obtained by driving the buses on VTT's heavy duty chassis dynamometer applying the transient Braunschweig city cycle. The vehicles were a representative set of Euro 2 to 3 emission categories, supplemented with Euro 4-5 (EEV) -targeted CRT, CNG and DPF cars. Particle number emissions from Euro 4 to 5 buses were 1/100-1/1000 and mass emissions 1/10-1/100 of those of the current fleet. Particle emission from natural gas buses and after an advanced CRT trap contained almost entirely liquid < 60 nm nano particles, which will make filter mass based PM control very challenging in the near future. One result was that gravimetric PM emission could ...

2006-10-15

304

MRI of liposarcomas. Observations on 28 liposarcomas; Magnetresonanztomographie der Liposarkome. Beobachtungen an 28 Liposarkomen  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Liposarcoma is the most common soft tissue sarcoma in adults. The purpose of the study was to correlate MR imaging features with the four ICD subclasses. Methods: 28 patients with liposarcoma were examined preoperatively on a 1.0 T MRI system, using spin echo sequences, gradient echo imaging and STIR sequences. In all patients, classification of the liposarcomas was made by histologic diagnosis (ICD-10-M-classification). Results: Well differentiated liposarcomas (9 patients) showed a number of MRI features consistent with lipoma (well defined mass high signal intensity (SI) on T{sub 1} images, low signal on T{sub 2} images, no or only little signal increase of tumour tissue after contrast material application, no necrosis). Not well differentiated liposarcomas (myxoid 14 patients, pleomorphic three patients, round cell two patients) revealed the largest part of the mass to be of low SI on T{sub 1}-weighted images. Only scattered fatty islands and septa (9 ...

1996-08-01

305

The correlation between accelerated and field corrosion tests performed in carbon steel and weathering steel coupons, coated and non-coated; Correlacao entre ensaios acelerados e ensaios de campo em corpos-de-provas de aco carbono e aco patinavel, sem e com revestimento  

Energy Technology Data Exchange (ETDEWEB)

The performance of four different organic coating systems applied to carbon and weathering steel coupons has been assessed in this investigation. applied on the surface of carbon steel and weathering steel coupons. The coupons have been evaluated using five different tests, three field tests and two accelerated tests. The field tests were carried out at three atmospheric stations, located at COSIPA in Cubatao-SP, at Alto da Serra in Cubatao-SP and at Paula Souza in Sao Paulo city. The accelerated tests consisted of (a) exposure to alternate cycles of ultraviolet radiation/condensation combined with salt spray cycles (UVCON combined with Salt Spray) and of (b) exposure to alternate cycles of ultraviolet radiation/condensation combined with the Prohesion test. The performance of the coatings was assessed by visual observation and photographs, using a method based on ASTM D-610, ASTM D-714 and ASTM-1654 standards to rank them. The oxide phases formed on the surfaces of the non-coated ...

2002-07-01

306

Potential of sub-ablative pulsed CO{sub 2} laser irradiation on inhibition of artificial caries-like lesion progress in bovine dental enamel; Potencial de inibicao da progressao da carie artificial por irradiacao sub-ablativa com laser de CO{sub 2} pulsado em esmalte dental bovino  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study was to investigate whether sub-ablative pulsed C0{sub 2} laser (1 0,6 {mu}m) irradiation is capable of reducing the susceptibility of the dental enamel to demineralization, and thus achieving a potential caries-protective effect. The crowns of 51 bovine front teeth, embedded in acrylic resin and polished until exposure of flat enamel surface, were used. The samples were cut in cubes of 10x10 mm, and totally coated with acid-resistant nail varnish, except for an enamel exposed window of 16 mm square. Three groups (n=17) were obtained: control group (CG) not irradiated; group laser A (LA) and group laser B (LB) where the samples were irradiated. The conditions were 60 mJ, 100 Hz, 0,3 J/cm{sup 2} for LA and 135 mJ, 10 Hz, 0,7 J/cm{sup 2} for LB. Two samples of each group were submitted to SEM analysis and fifteen to demineralization in 3 ml acetate buffer solution (0,1 mol/L) with pH 4,5 for 24h at 37 deg C, with regular agitation. After the specimens were removed ...

2005-07-01