WorldWideScience
1

Accurate convolution/superposition for multi-resolution dose calculation using cumulative tabulated kernels  

International Nuclear Information System (INIS)

Convolution/superposition (C/S) is regarded as the standard dose calculation method in most modern radiotherapy treatment planning systems. Different implementations of C/S could result in significantly different dose distributions. This paper addresses two major implementation issues associated with collapsed cone C/S: one is how to utilize the tabulated kernels instead of analytical parametrizations and the other is how to deal with voxel size effects. Three methods that utilize the tabulated kernels are presented in this paper. These methods differ in the effective kernels used: the differential kernel (DK), the cumulative kernel (CK) or the cumulative-cumulative kernel (CCK). They result in slightly different computation times but significantly different voxel size effects. Both simulated and real multi-resolution dose calculations are presented. For simulation tests, we use arbitrary kernels and various voxel sizes ...

2005-02-21

2

Introducing DeBRa: a detailed breast model for radiological studies  

Energy Technology Data Exchange (ETDEWEB)

Currently, x-ray mammography is the method of choice in breast cancer screening programmes. As the mammography technology moves from 2D imaging modalities to 3D, conventional computational phantoms do not have sufficient detail to support the studies of these advanced imaging systems. Studies of these 3D imaging systems call for a realistic and sophisticated computational model of the breast. DeBRa (Detailed Breast model for Radiological studies) is the most advanced, detailed, 3D computational model of the breast developed recently for breast imaging studies. A DeBRa phantom can be constructed to model a compressed breast, as in film/screen, digital mammography and digital breast tomosynthesis studies, or a non-compressed breast as in positron emission mammography and breast CT studies. Both the cranial-caudal and mediolateral oblique views can be modelled. The anatomical details inside the phantom include the lactiferous ...

2009-07-21

3

Convolution/superposition using the Monte Carlo method  

International Nuclear Information System (INIS)

The convolution/superposition calculations for radiotherapy dose distributions are traditionally performed by convolving polyenergetic energy deposition kernels with TERMA (total energy released per unit mass) precomputed in each voxel of the irradiated phantom. We propose an alternative method in which the TERMA calculation is replaced by random sampling of photon energy, direction and interaction point. Then, a direction is randomly sampled from the angular distribution of the monoenergetic kernel corresponding to the photon energy. The kernel ray is propagated across the phantom, and energy is deposited in each voxel traversed. An important advantage of the explicit sampling of energy is that spectral changes with depth are automatically accounted for. No spectral or kernel hardening corrections are needed. Furthermore, the continuous sampling of photon direction allows us to model sharp changes in ...

2003-07-21

4

Fluence-convolution broad-beam (FCBB) dose calculation  

International Nuclear Information System (INIS)

IMRT optimization requires a fast yet relatively accurate algorithm to calculate the iteration dose with small memory demand. In this paper, we present a dose calculation algorithm that approaches these goals. By decomposing the infinitesimal pencil beam (IPB) kernel into the central axis (CAX) component and lateral spread function (LSF) and taking the beam's eye view (BEV), we established a non-voxel and non-beamlet-based dose calculation formula. Both LSF and CAX are determined by a commissioning procedure using the collapsed-cone convolution/superposition (CCCS) method as the standard dose engine. The proposed dose calculation involves a 2D convolution of a fluence map with LSF followed by ray tracing based on the CAX lookup table with radiological distance and divergence correction, resulting in complexity of O(N"3) both spatially and temporally. This simple algorithm is orders of magnitude faster than the CCCS method. Without pre-calculation of beamlets, its ...

2010-12-07

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(In Japanese)?????????????????????????  

J-STORE (Japan)

Full Text Available

2009-12-25

13

(In Japanese)???????????????????????  

J-STORE (Japan)

Full Text Available

2010-01-12

14

(In Japanese)??????????????????????  

J-STORE (Japan)

Full Text Available

2010-12-21

15

(In Japanese)???????????????????  

J-STORE (Japan)

Full Text Available

2008-06-27

16

(In Japanese)?????????????????  

J-STORE (Japan)

Full Text Available

2010-01-12

17

(In Japanese)???????????????  

J-STORE (Japan)

Full Text Available

2011-07-01

18

(In Japanese)???????????????  

J-STORE (Japan)

Full Text Available

2010-07-23

19

(In Japanese)????????????  

J-STORE (Japan)

Full Text Available

2011-04-05

20

(In Japanese)?????????  

J-STORE (Japan)

Full Text Available

2011-04-27

21

Monte Carlo simulation and scatter correction of the GE Advance PET scanner with SimSET and Geant4  

Energy Technology Data Exchange (ETDEWEB)

For Monte Carlo simulations to be used as an alternative solution to perform scatter correction, accurate modelling of the scanner as well as speed is paramount. General-purpose Monte Carlo packages (Geant4, EGS, MCNP) allow a detailed description of the scanner but are not efficient at simulating voxel-based geometries (patient images). On the other hand, dedicated codes (SimSET, PETSIM) will perform well for voxel-based objects but will be poor in their capacity of simulating complex geometries such as a PET scanner. The approach adopted in this work was to couple a dedicated code (SimSET) with a general-purpose package (Geant4) to have the efficiency of the former and the capabilities of the latter. The combined SimSET+Geant4 code (SimG4) was assessed on the GE Advance PET scanner and compared to the use of SimSET only. A better description of the resolution and sensitivity of the scanner and of the scatter fraction was obtained with SimG4. ...

2005-10-21

22

On the accuracy and effectiveness of dose reconstruction for tomotherapy  

International Nuclear Information System (INIS)

Dose reconstruction is a process that re-creates the treatment-time dose deposited in a patient provided there is knowledge of the delivered energy fluence and the patient's anatomy at the time of treatment. A method for reconstructing dose is presented. The process starts with delivery verification, in which the incident energy fluence from a treatment is computed using the exit detector signal and a transfer matrix to convert the detector signal to energy fluence. With the verified energy fluence and a CT image of the patient in the treatment position, the treatment-time dose distribution is computed using any model-based algorithm such as convolution/superposition or Monte Carlo. The accuracy of dose reconstruction and the ability of the process to reveal delivery errors are presented. Regarding accuracy, a reconstructed dose distribution was compared with a measured film distribution for a simulated breast treatment carried out on a thorax phantom. It was found ...

2001-04-01

23

Improvement of spatial resolution in the longitudinal direction for isotropic imaging in helical CT  

Energy Technology Data Exchange (ETDEWEB)

Experiments were conducted to confirm the isotropic spatial resolution of multislice CT with a 0.5 mm slice thickness. Isotropic spatial resolution means that the spatial resolution in the transaxial plane (X-Y plane) and that in the longitudinal direction (Z direction) are equivalent. To obtain point spread function (PSF) values in the X-Y-Z directions, three-dimensional voxel data were obtained by helical scanning of a bead phantom. The modulation transfer function (MTF) values were then obtained by three-dimensional Fourier transform of the PSF. Evaluation of the spatial resolution in the X-Y-Z directions by the MTF values showed that the spatial resolution in the Z direction does not depend on the reconstruction kernel used. It was also found that the spatial resolution in the Z direction, as compared with that in the X-Y plane, is superior with the standard kernel for the abdomen and is inferior with the high-definition kernel for the ...

2007-02-07

25

Moxel: A molar tooth voxel model for dosimetric studies  

Energy Technology Data Exchange (ETDEWEB)

Stylized numerical models of the tooth are usually employed in qualification procedure related to Electronic Paramagnetic Resonance in long-term accidental contamination dose reconstruction. In this work a voxel model was developed from the microCT image data set of a human non contaminated molar tooth. A stylized model, reproducing the characteristics of the voxel model, was also created in order to investigate the level of accuracy that can be obtained in this kind of study.

2010-02-15

26

A stochastic convolution/superposition method with isocenter sampling to evaluate intrafraction motion effects in IMRT  

International Nuclear Information System (INIS)

Current methods to calculate dose distributions with organ motion can be broadly classified as 'dose convolution' and 'fluence convolution' methods. In the former, a static dose distribution is convolved with the probability distribution function (PDF) that characterizes the motion. However, artifacts are produced near the surface and around inhomogeneities because the method assumes shift invariance. Fluence convolution avoids these artifacts by convolving the PDF with the incident fluence instead of the patient dose. In this paper we present an alternative method that improves the accuracy, generality as well as the speed of dose calculation with organ motion. The algorithm starts by sampling an isocenter point from a parametrically defined space curve corresponding to the patient-specific motion trajectory. Then a photon is sampled in the linac head and propagated through the three-dimensional (3-D) collimator structure corresponding to a particular MLC segment chosen randomly from ...

2005-04-01

27

Multidimensional B-spline parameterization of the detection probability of PET systems to improve the efficiency of Monte Carlo simulations  

International Nuclear Information System (INIS)

Accurate modeling of system response and scatter distribution is crucial for image reconstruction in emission tomography. Monte Carlo simulations are very well suited to calculate these quantities. However, Monte Carlo simulations are also slow and many simulated counts are needed to provide a sufficiently exact estimate of the detection probabilities. In order to overcome these problems, we propose to split the simulation into two parts, the detection system and the object to be imaged (the patient). A so-called 'virtual boundary' that separates these two parts is introduced. Within the patient, particles are simulated conventionally. Whenever a photon reaches the virtual boundary, its detection probability is calculated analytically by evaluating a multi-dimensional B-spline that depends on the photon position, direction and energy. The unknown B-spline knot values that define this B-spline are fixed by a prior 'pre-' simulation that needs to be run once for each scanner type. After ...

2010-06-21

28

Monte Carlo simulation and dosimetric verification of radiotherapy beam modifiers  

International Nuclear Information System (INIS)

Monte Carlo simulation of beam modifiers such as physical wedges and compensating filters has been performed with a rectilinear voxel geometry module. A modified version of the EGS4/DOSXYZ code has been developed for this purpose. The new implementations have been validated against the BEAM Monte Carlo code using its standard component modules (CMs) in several geometrical conditions. No significant disagreements were found within the statistical errors of 0.5% for photons and 2% for electrons. The clinical applicability and flexibility of the new version of the code has been assessed through an extensive verification versus dosimetric data. Both Varian multi-leaf collimator (MLC) wedges and standard wedges have been simulated and compared against experiments for 6 MV photon beams and different field sizes. Good agreement was found between calculated and measured depth doses and lateral dose profiles along both wedged and unwedged directions for different depths and ...

2001-11-01

30

Determinations of organ or tissue doses to survivors in Hiroshima and Nagasaki  

International Nuclear Information System (INIS)

For the purpose of risk estimates from radiation carcinogenesis including leukemogenesis and radiation genetic effects, the biological significant dose is not the tissue kerma in air but the absorbed dose in organ or tissue with respect to carcinogenic and leukemogenic effects or genetic effects. In order to estimate organ or tissue dose from the tissue kerma in air, a ratio of the organ or tissue dose to the tissue kerma in air for survivors in Hiroshima and Nagasaki was calculated with the aid of the Snyder's mathematical phantoms constructed so as to simulate the body shape of survivors aged 5, 10 years old and adult at the time of atomic bomb detonations. The ratios were corrected for the angular distribution of atomic bomb radiations, assuming an anisotropic angular distribution for the survivors exposed to the atomic bombs in open air and the isotropic distribution for the survivors incide a Japanese house or other structures. The ...

1980-01-01

31

Concepts of radiotherapy treatment planning  

International Nuclear Information System (INIS)

Full text: Radiotherapy treatment planning (RTP) relies heavily on medical imaging. Until recently, the most important planning tool was the treatment simulator. The kilovoltage radiographic capabilities in a treatment simulator enabled the boundaries of treatment fields to be visualized with respect to bony anatomic landmarks. Perhaps the most important advance in treatment planning in recent years is the ability to visualize the passage of the beams with respect to a more accurate geometrical representation of the tumor and other soft tissue structures. This 'virtual simulation' uses a computer-based representation of a patient to determine the extent of the disease and the location of radiation sensitive normal tissue. Computer tomographic (CT) imaging produces a high-resolution three-dimensional representation of anatomy that can be correlated with other image sets such as magnetic resonance images (MRI) of function. Positron emission tomographic (PET) imaging is beginning to be ...

2000-12-01

32

Three-dimensional image display of brain tumor utilizing a modified voxel method  

Energy Technology Data Exchange (ETDEWEB)

The patch and voxel methods are representative examples of the ways in which multi-slice images may be displayed three-dimensionally by means of computer-graphics. Each of them have advantages and disadvantages and they are mutually complementary. We have developed algorithms for a modified voxel method which incorporates the advantages of the patch methods. We have applied this to the three-dimensional image display of brain tumor with excellent results. The three-dimensional reconstructions used for clinical application in this study were derived from X-ray CT images.

1988-08-01

33

Artery phantoms for intravascular optical coherence tomography: healthy arteries  

UK PubMed Central (United Kingdom)

We present a method to make phantoms of coronary arteries for intravascular optical coherence tomography (IV-OCT). The phantoms provide a calibrated OCT response similar to the layered structure of...Full Text Available

34

On the sensitivity of IMRT dose optimization to the mathematical form of a biological imaging-based prescription function  

UK PubMed Central (United Kingdom)

Voxel-based prescriptions of deliberately non-uniform dose distributions based on molecular imaging, so-called dose painting or theragnostic radiation therapy, require specification of a transformation...Full Text Available

2009-03-21

35

Radiation effects on the shoot tip culture of chrysanthemum  

International Nuclear Information System (INIS)

Japanese (Mar 1974). Japan Mabuchi, Toshio Kuwada, Hikaru . Kagawa Univ.,

37

Fundamental study on Fuji Computed Radiography (FCR) image  

International Nuclear Information System (INIS)

Japanese (Mar 1986). Japan Tomiyoshi, Tsukasa Kakoi, Iwao Fukushima,

1986-01-01

39
41

Importance of anthropomorphic phantoms in nuclear medicine  

International Nuclear Information System (INIS)

... Brasileira de Biociencias Nucleares (SBBN), Recife, PE (Brazil) INIS-BR--9282

2010-10-27

42

Getting America Ready for Japanese Science and Technology.  

Science.gov (United States)

The proceedings of a conference on the development of language capabilities to prepare United States scientists to share in scientific and technological development with Japan include these papers: "Are Japanese Language Programs Reaching Scientists and Engineers?"; "Japanese Language Study for Engineers: High Tech Perspectives"; "Applied Japanese Studies for Science and Engineering at American Universities"; "Training and Certifying Japanese Technical Translators"; "Designing Effective Language Teaching for Professionals"; "Problems in Teaching Technical Japanese"; "Commentary" A Cautious and Deliberate Strategy Is Needed"; "Establishing a Japanese High-Technology Information Company in the United States"; "The Problems of Operating a Technical Translation Company in Japan";"The Japan Information Center of Science and Technology"; "A National Agenda for ...

1985-05-15

43

Evaluation of the 1Shot Phantom dedicated to the mammography system using FCR  

International Nuclear Information System (INIS)

Currently daily quality control (QC) tests for mammography systems are generally evaluated by using visual analysis phantoms, which of course means subjective measurement. In our study, however, we evaluated a novel digital phantom, the 1Shot Phantom M plus (1Shot Phantom), together with automatic analysis software dedicated for mammography systems using Fuji computed radiography (FCR). The digital phantom enables objective evaluation by providing for actual physical measurement rather than subjective visual assessment. We measured contrast to noise ratio (CNR), image receptor homogeneity, missed tissue at chest wall side, modulation transfer function (MTF), and geometric distortion utilizing the 1Shot Phantom. We then compared the values obtained using the 1Shot Phantom with values obtained from the European guidelines and International ...

2009-07-01

44

Poor Work Environments and Nurse Inexperience Are Associated with Burnout, Job Dissatisfaction, and Quality Deficits in Japanese Hospitals  

UK PubMed Central (United Kingdom)

AimsTo describe nurse burnout, job dissatisfaction, and quality of care in Japanese hospitals, and to determine how these outcomes are associated with work environment...Full Text Available

2008-12-01

45

Paraquat-induced resinosis in Japanese pine. I. The effect of paraquat on Pinus densiflora and P. thunbergii  

Energy Technology Data Exchange (ETDEWEB)

Treatment of Japanese pines (P. densiflora and P. thunbergii) with paraquat induced a zone of lightwood. Determinations of turpentine and ether extractives contents in lightwoods showed high levels as compared with those in control woods. (Refs. 5).

1980-01-01

46

NSF/Tokyo Report: Japanese Government Budget for Materials R&D  

Science.gov (United States)

... Tokyo Report: Japanese Government Budget for Materials R&D Date: 6/17/97 The National Science ... Graded Materials Area coordinator: Dr. Toshio Hirai, Professor, Institute for Materials Research ...

47

Macular and retinal nerve fiber layer thickness in Japanese measured by Stratus optical coherence tomography  

UK PubMed Central (United Kingdom)

The purpose of this study was to determine the thickness of the macula and the retinal nerve fiber layer (RNFL) in Japanese subjects by Stratus optical coherence tomography (OCT), and to compare the...Full Text Available

2007-06-01

48

DNA alterations detected in the progeny of paternally irradiated Japanese medaka fish (Oryzias latipes).  

UK PubMed Central (United Kingdom)

A nonmammalian test system for germ-cell mutagenesis has been developed by using the Japanese medaka fish. We describe a system for detecting DNA alterations in F1 progeny descended from the gamma-irradiated...Full Text Available

1995-01-03

49

Theme and policy for international development of Japanese nuclear energy industries  

International Nuclear Information System (INIS)

Aug 2010 p. 31-35 Japan Kishioka, Kazuhiko Japan Atomic Industrial Forum,

2010-08-01

50

Nuclear forensics. The science for enhancing nuclear security  

International Nuclear Information System (INIS)

Japanese ... Authors Kuno, Yusuke; Esaka, Konomi (Tokyo Univ., Graduate School of Engineering, Tokyo (Japan))

2011-01-01

51

Femoral neck fracture after irradiation therapy  

International Nuclear Information System (INIS)

Japanese Mar 1999 p. 371-372 Japan Shi, Dequan Yamazaki, Takashi

1999-03-01

52

Crisis communication on nuclear facilities and addressing media  

International Nuclear Information System (INIS)

Japanese May 2009 p. 386-390 Japan Mitani, Shinji Japan Nuclear Energy

2009-05-01

54

Shuttle Showcase: STS-124  

National Aeronautics and Space Administration (NASA)

The second in a series of flights to assemble the Japanese segment of the International Space Station saw the mammoth Kibo module delivered to the complex complements of Discovery and its crew on the STS-124 mission. Kibo, the Japanese word for u201chopeu201d would house dozens of experiments and serve as a platform for external payloads brought to the complex on subsequent Shuttle flights and the Japanese u201cKounotoriu201d H-2 Transfer Vehicle cargo ship.

2011-07-10

55

Phantom simulation device for scintillation cameras  

Energy Technology Data Exchange (ETDEWEB)

A phantom simulation imaging quality control device is described that effectively simulates one centimeter lesions, using steel ball bearings as gamma ray attenuators. The bearings are mounted in a synthetic resinous sheet in an orthogonal pattern. The phantom can provide uniformity, resolution, linearity, distortion and field size checks, all with a single exposure.

1981-08-25

56

Comparative Study of SVM Methods Combined with Voxel Selection for Object Category Classification on fMRI Data  

UK PubMed Central (United Kingdom)

BackgroundSupport vector machine (SVM) has been widely used as accurate and reliable method to decipher brain patterns from functional MRI (fMRI) data. Previous studies have not...Full Text Available

57

A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice  

UK PubMed Central (United Kingdom)

Amyloid plaques are a characteristic feature in Alzheimer’s disease (AD). A novel non-toxic contrast agent is presented, Gd-DTPA-K6Aβ1–30, which is homologous to Aβ,...Full Text Available

2008-06-01

58

Dose verification using a pelvic phantom in high dose rate (HDR) brachytherapy  

Energy Technology Data Exchange (ETDEWEB)

High dose rate (HDR) brachytherapy for treating a cervix carcinoma has become popular, because it eliminates many of the problems associated with conventional brachytherapy. In order to improve the clinical effectiveness with HDR brachytherapy, a dose calculation algorithm, optimization procedures, and image registrations need to be verified by comparing the dose distributions from a planning computer and those from a humanoid phantom. In this study, the humanoid phantom was fabricated in order to verify the absolute doses and the relative dose distributions. The measured doses from the humanoid phantom were then compared with the treatment planning system for the dose verification. The humanoid phantom needs to be designed such that the dose distributions can be quantitatively evaluated thermoluminescent dosimeter (TLD) chips with a dimension of 1/8 and film dosimetry with a spatial resolution of ...

2003-07-01

59

Exploration of exposure dose optimization for pelvic examination in direct digital radiography with a phantom  

International Nuclear Information System (INIS)

Objective: To investigate the relationship between exposure dose and image quality for a direct digital radiography system and to determine the optimum exposure parameters for pelvic examination. Methods: A contrast-detail phantom CDRAD2.0 was exposed to different doses and the IQF of phantom images were calculated. The optimum exposure parameters were determined by ANOVA and SNK analysis. The image of an anthropomorphic phantom taken with optimized exposure parameters was verified using CEC image criteria. Results: The IQF of the images of CDRAD2.0 phantom was significantly different for different doses, as the exposure dose was greater than 0.61 mGy. The IQFs have no difference for different dose groups. The image quality between this optimized exposure dose and conventional exposure dose not was significantly different. Conclusion: The image quality of direct digital radiography system is improved as ...

2005-10-01

60

Phase-space analysis of interacting phantom cosmology  

CERN Document Server

We perform a detailed phase-space analysis of various phantom cosmological models, where the dark energy sector interacts with the dark matter one. We examine whether there exist late-time scaling attractors, corresponding to an accelerating universe and possessing dark energy and dark matter densities of the same order. We find that all the examined models, although accepting stable late-time accelerated solutions, cannot alleviate the coincidence problem, unless one imposes a form of fine-tuning in the model parameters. It seems that interacting phantom cosmology cannot fulfill the basic requirement that led to its construction.

2008-01-01

61

Phantom dark energy with varying-mass dark matter particles: acceleration and cosmic coincidence problem  

CERN Document Server

We investigate several varying-mass dark-matter particle models in the framework of phantom cosmology. We examine whether there exist late-time cosmological solutions, corresponding to an accelerating universe and possessing dark energy and dark matter densities of the same order. Imposing exponential or power-law potentials and exponential or power-law mass dependence, we conclude that the coincidence problem cannot be solved or even alleviated. Thus, if dark energy is attributed to the phantom paradigm, varying-mass dark matter models cannot fulfill the basic requirement that led to their construction.

2009-01-01

62

Understanding Japanese society through life after death  

British Library Electronic Table of Contents (United Kingdom)

In this article based on extensive ethnographic interviewing of eighty-six Japanese adults, I analyze the different ways in which they understand life after death, and consider the societal implications of their views. I examine senses of life after death as based in communion with departed family members as linked to practices of ancestor veneration and ideologies of Japaneseness. I consider heaven/hell or reincarnation as linked, through the idea of impartial judgment of the individual, to meritocracy and the examination system. I examine agnosticism and relativism in senses of life after death as linked to the idea that individual freedom of choice may exist in the next world if not necessarily within the constraints of this Japanese world. I examine disbelief in any realm beyond the gr...

2011-01-01

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THE JAPANESE LABOR BOSS SYSTEM. A DESCRIPTION ...  

Science.gov (United States)

... The following report, filed by the Labor Inspector of the local Employment Security Office, cites S3 me of "the harsh disciplinary methods used by the ...

1953-04-01

66

Past Its Prime? The Future of the US-Japan Alliance  

Science.gov (United States)

... The Aum Shinryko sarin gas attack on the Ginza Subway line in Tokyo in 1995 brought home to the Japanese a sense of immediate vulnerability. ...

2004-02-09

68

Morphine versus Mexiletine for Treatment of Postamputation Pain  

UK PubMed Central (United Kingdom)

BackgroundStump and phantom pains are debilitating sequelae of amputations that are often resistant to treatment. The efficacy of pharmacologic therapies, including...Full Text Available

2008-08-01

69

Comparing dose calculation algorithms for an orthovoltage beam in a bone phantom  

International Nuclear Information System (INIS)

The aim of this work was to compare dose calculation algorithm results at orthovoltage energies for a phantom composed of a bone slab in water. The calculation methods investigated were: no correction, ETAR, Batho, convolution/superposition and Monte Carlo. All algorithms calculated depth dose curves in a water phantom within 4% of experiment. However in the bone phantom, differences of over 40% between the No Correction / ETAR / Batho / Convolution and Monte Carlo results in the 1 cm thick bone slab were observed. These differences are predominantly because the algorithms do not account for the differing atomic number of the bone compared to water The increased dose to bone and the tissue adjacent to the bone interface should be considered when treating with orthovoltage photons. Copyright (1998) Australasian Physical and Engineering Sciences in Medicine

1998-09-01

70

Chronic Pain Associated with Upper-Limb Loss  

UK PubMed Central (United Kingdom)

ObjectiveTo describe the prevalence, intensity, and functional impact of the following types of pain associated with upper-limb loss: phantom limb, residual limb,...Full Text Available

2009-09-01

71

Future of the Japanese steel industry and a suggestion to the Canadian coal industry  

Energy Technology Data Exchange (ETDEWEB)

Discussion is presented of world crude steel production, the Japanese steel industry and its expectations of the Canadian coal industry. It is concluded that the Canadian coal industry should pay attention to the trend in customer's requirements regarding coal quality, maintain price competitiveness in the international market place, and remain flexible with regard to the market trend.

1989-01-01

72

Fuel-related advances in science and technology. (XI) Commerce. (3) Changes in coal liquefaction projects and the future outlook  

Energy Technology Data Exchange (ETDEWEB)

Accounts are given of the history of coal liquefaction research and projects (indirect liquefaction, direct liquefaction, plus the recent state of Japanese developments and of process development), and of the significance of the petroleum age, the energy crisis and of coal liquefaction itself. (10 refs.) (In Japanese)

1982-01-01

73

Development of coal utilization technology in the Japanese steel industry - co-operation with coal suppliers  

Energy Technology Data Exchange (ETDEWEB)

Past and current development of coal utilization technology in the Japanese steel industry is reviewed and some projects currently under research and development briefly described. These include DIOS, an iron making process which directly utilizes both iron ore and coal without a sintering plant or a coke oven; and the development of a new generation coke oven. 15 figs.

1994-12-31

74

Optimization of segment weight using simulated dynamics algorithm for beamlet-based IMRT  

International Nuclear Information System (INIS)

With accurate calculation algorithms in inverse planning for beamlet-based intensity modulated radiotherapy (IMRT), it takes time to calculate the dose matrix, which represents the dose distribution of each beamlet element to each voxel for unit fluence. To reduce the calculation time, coarse or approximate algorithms are often a choice, but this results in a final dose distribution that cannot reflect the real value. In addition, it is necessary to test if a coarse algorithm is capable of calculating the dose matrix of beamlets. In this work, simulated dynamics optimization algorithm was applied to optimize the segment weight to minish the dose error from the dose matrix calculation. After calculating the dose matrix by ray-tracing algorithm which takes into account just the primary component of absorbed dose, the original beam profile intensity distribution was optimized by using the simulated dynamics algorithm. Before segmentation, the even-spaced algorithm and ...

2007-08-01

75

Endoluminal ultrasound applicator with an integrated RF coil for high-resolution magnetic resonance imaging-guided high-intensity contact ultrasound thermotherapy  

International Nuclear Information System (INIS)

High-intensity contact ultrasound (HICU) under MRI guidance may provide minimally invasive treatment of endocavitary digestive tumors in the esophagus, colon or rectum. In this study, a miniature receive-only coil was integrated into an endoscopic ultrasound applicator to offer high-resolution MRI guidance of thermotherapy. A cylindrical plastic support with an incorporated single element flat transducer (9.45 MHz, water cooling tip) was made and equipped with a rectangular RF loop coil surrounding the active element. The integrated coil provided significantly higher sensitivity than a four-element extracorporeal phased array coil, and the standard deviation of the MR thermometry (SDT) improved up to a factor of 7 at 10 mm depth in tissue. High-resolution morphological images (T1w-TFE and IR-T1w-TSE with a voxel size of 0.25 x 0.25 x 3 mm3) and accurate thermometry data (the PRFS method with a voxel size of 0.5 x 0.5 x 5 mm3, 2.2 s/image, 0.3 ...

2008-11-21

76

Study on the use of coal ash reclaimed land as upland-fields (Part 2)  

Energy Technology Data Exchange (ETDEWEB)

Soil dressing on coal ash reclaimed land is a covering to use the land for agriculture. This study was carried out to find out the necessary depth of soil covering the ash layer in order to have normal crop growth. Two kinds of crops, Japanese radish, and rakkyo were planted in cover soil on the fly ash packed in wooden boxe (90 cm x 90 cm x 90 cm). Depths of cover soil were 20 cm, 30 cm, 40 cm and 50 cm. The results were summarized as follows: growth and yield of Japanese radish and rakkyo were increased with increasing depth of cover soil; root development of Japanese radish was inhibited at the lower coal ash layer. Main root length and edible root length of Japanese radish were decreased with decreasing depth of cover soil; boron and molybdenum contents in the plants remarkably increased with decreasing depth of cover soil. This may be due to the absorption of these elements from fly ash layer; it ...

1987-01-01

77

Telescope performance near local midnight for the Japanese Advanced Meteorological Imager (JAMI)  

Science.gov (United States)

Raytheon's Santa Barbara Remote Sensing (SBRS) division designed and built the MTSAT-1R Japanese Advanced Meteorological Imager for the Japanese Ministry of Transport between March, 1999 and July, 2002. In order to meet the stressing requirements of a geosynchronous orbit, a combination of structural, thermal, and optical (STOP) analyses were used to design and optimize the beryllium three-mirror anastigmat (TMA) telescope. This modeling approach was used to characterize and minimize the thermal distortion around local midnight. On-orbit temperatures and structural deformations were predicted using thermal Desktop/SINDA and PATRAN/NASTRAN software, respectively. The resulting optical performance was evaluated using Raytheon developed HEXAGON software. The telescope design was successfully optimized to attain specified visible channel performance for most of the 24 hour orbit.

2005-01-01

78

Some issues on Japanese nuclear armament  

International Nuclear Information System (INIS)

The author considers the possibility that Japanese nuclear armament might be a realistic political option. Firstly introducing various issues on Japanese nuclear armament existing since long time ago, he classifies them according to the view point from internal and international problems. Internally, the armament is not possible at present on the ground of the nation's non-nuclear policy but it might be conditionally a choice in such case as the reliability of US nuclear deterrence declines or possibility of nuclear attack to Japan actually may be predicted. The armament may be possible technically and legally based on the consensus of the people. Various concerns by neighboring countries are discussed. Finally, the author stresses the importance of continuing to consolidate bilateral relationship with US, to deploy missile defensive system and to make every effort in the diplomatic activity for strong international ties and cooperation. (S. ...

2007-07-01

79

Effect of nonsteroidal anti-inflammatory drug plasters for knee osteoarthritis in Japanese: a randomized controlled trial  

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to examine the effect of a nonsteroidal anti-inflammatory drug (NSAID) plaster for knee osteoarthritis among Japanese patients. An open-labeled, randomized, controlled, multiclinic trial was performed involving outpatient clinic groups. Two comparative groups?plaster NSAIDs and oral NSAIDs?were randomly allocated. The drugs used were limited to the current top three in both groups in Japan. Treatments were assessed after four?weeks and compared with the baseline scores. Outcomes were evaluated by two psychometric measures: Japanese knee osteoarthritis measure, and pain with the visual analogue scale. The total number of patients included in the final evaluation was 165 (87 for the plaster group and 78 for the oral group). Between these two groups there were ...

2010-01-01

80

Pulsed Radiofrequency Ablation for Residual and Phantom Limb Pain: A Case Series  

British Library Electronic Table of Contents (United Kingdom)

Abstract Residual limb pain (RLP) and phantom limb pain (PLP) can be debilitating and can prevent functional gains following amputation. High correlations have been reported between RLP and the stump neuromas following amputation. Many treatment methods including physical therapy, medications, and interventions, have been used with limited success. Pulsed radiofrequency ablation (PRFA) has shown promise in treating neuropathic pain because of the inhibition of evoked synaptic activity. We present 4 amputees who were treated with PRFA after failing conservative management for their RLP and PLP. All 4 patients underwent PRFA and demonstrated at least 80% relief of RLP for over 6 months. One patient reported a complete resolution of phantom sensation while another patient had significantly de...

2010-01-01

81

Monte Carlo simulations incorporating Mie calculations of light transport in tissue phantoms: Examination of photon sampling volumes for endoscopically compatible fiber optic probes  

Energy Technology Data Exchange (ETDEWEB)

Details of the interaction of photons with tissue phantoms are elucidated using Monte Carlo simulations. In particular, photon sampling volumes and photon pathlengths are determined for a variety of scattering and absorption parameters. The Monte Carlo simulations are specifically designed to model light delivery and collection geometries relevant to clinical applications of optical biopsy techniques. The Monte Carlo simulations assume that light is delivered and collected by two, nearly-adjacent optical fibers and take into account the numerical aperture of the fibers as well as reflectance and refraction at interfaces between different media. To determine the validity of the Monte Carlo simulations for modeling the interactions between the photons and the tissue phantom in these geometries, the simulations were compared to measurements of aqueous suspensions of polystyrene microspheres in the wavelength range 450-750 nm.

1996-04-01

82

Estimated fetal radiation dose from multislice CT studies  

International Nuclear Information System (INIS)

It is often necessary to estimate the dose of radiation to a fetus from a series of CT scans. To assist in making this process easier and more accurate, we measured fetal doses in an adult anthropomorphic phantom for four CT scanners: Picker 1200, Siemens DRH, GE 9800, and GE 8800. Measurements were made at four kilovoltages (100, 120, 130, and 140 kVp), for 2-, 5-, 8-, and 10-mm thicknesses, for two scanning angles (360 degrees and 398 degrees) and for two patient orientations (prone and supine). The fetal-dose estimates are based on the CT dose index measured by using a pencil ionization chamber at the center position of a 16-cm-diameter cylindrical phantom. Comparison with data from other investigators shows reasonable agreement when phantom differences, X-ray tube output, and equipment calibration are considered.

83

Dose enhancement in bone in electron beam therapy  

Energy Technology Data Exchange (ETDEWEB)

This study investigated dose to bone tissue in electron beam therapy. Measurements were made using films and thermoluminescent dosimeters in a polystyrene phantom containing bone inhomogeneity for 15-MeV, 12-MeV, and 9-MeV electron beams. An increase in dose of approximately 18%, 12%, and 11%, for the three electron energies respectively, relative to the dose in polystyrene, was found for bone material having an electron density (relative to water) of 1.73. Measurements were also made using films for 15- and 9-Mev electrons in a phantom with a mandibular bone and teeth. A dose enhancement in bone of approximately 10% and 7%, respectively, for the two energies was found in the phantom where the electron density of bone was about 1.60. These results suggest that injury to bone is possible in those clinical situations where high doses of electrons are used for therapy.

1984-05-01

84

Dose enhancement in bone in electron beam therapy  

International Nuclear Information System (INIS)

This study investigated dose to bone tissue in electron beam therapy. Measurements were made using films and thermoluminescent dosimeters in a polystyrene phantom containing bone inhomogeneity for 15-MeV, 12-MeV, and 9-MeV electron beams. An increase in dose of approximately 18%, 12%, and 11%, for the three electron energies respectively, relative to the dose in polystyrene, was found for bone material having an electron density (relative to water) of 1.73. Measurements were also made using films for 15- and 9-Mev electrons in a phantom with a mandibular bone and teeth. A dose enhancement in bone of approximately 10% and 7%, respectively, for the two energies was found in the phantom where the electron density of bone was about 1.60. These results suggest that injury to bone is possible in those clinical situations where high doses of electrons are used for therapy.

85

cover.fm  

Wastenet

Incorporating Environmentally Conscious Materials Selection in CAD System Narito Shibaike, Matsushita Electric, Japan ...Ikeda, Matsushita Erectric H.Ishida, INAX Y.Ishikawa, Japan Techno-Economics ...Tsuchiya*, Matsushita Electric Com- ponents Y.Tsuchiya*, Society of Japanese Value

86

The Requirement for Sodium as a Micronutrient by Species Having the C4 Dicarboxylic Photosynthetic Pathway  

UK PubMed Central (United Kingdom)

Six species having characteristics of plants with the C4 dicarboxylic photosynthetic pathway, Echinochloa utilis L. Ohwi et Yabuno (Japanese millet), Cynodon dactylon...Full Text Available

1972-05-01

87

Swell opportunities for Japanese hydro  

Energy Technology Data Exchange (ETDEWEB)

Japan has upwards of 40 pumped storage plants in operation and new river sites are becoming scarce, but peak demand is still rising. A plant under construction in Okinawa offers a solution: make use of the head between the coastal cliffs and sea level, using seawater as the medium. (author)

1998-03-01

88

State-Space Modeling Indicates Rapid Invasion of an Alien Shrub in Coastal Dunes  

Science.gov (United States)

... uncertainty. The method is applied for the invasive shrub Rosa rugosa (Japanese rose) in Danish fixed dunes. The probability ... habitat code 2130). In 14 sites, the invasive shrub Rosa rugosa was recorde...

89

Sexual behavior in Japanese quail as a test end point for endocrine disruption: effects of in ovo exposure to ethinylestradiol and diethylstilbestrol.  

UK PubMed Central (United Kingdom)

Chemicals having a capacity to disturb the endocrine system have attracted considerable interest during recent years. There is a shortage of well-characterized in vivo tests with which to study such...Full Text Available

1999-11-01

90

Selective promotion of alternative energy forms - hopes for liquefaction of Australian brown coal. [Japan  

Energy Technology Data Exchange (ETDEWEB)

This report of an interview with T. Watamori, Chairman of the Board of Directors of the New Energy Development Organization (NEDO), Japan outlines the general activities of NEDO, and then gives emphasis to the prospects of the liquefaction of brown coal from Australia. (In Japanese)

1981-01-01

91

Rapid Action on Neuroplasticity Precedes Behavioral Activation by Testosterone  

UK PubMed Central (United Kingdom)

Testosterone has been shown to increase the volume of steroid-sensitive brain nuclei in adulthood in several vertebrate species. In male Japanese quail the volume of the male-biased sexually...Full Text Available

2008-09-01

92

Quantifiable Biomarkers of Normal Aging in the Japanese Medaka Fish (Oryzias latipes)  

UK PubMed Central (United Kingdom)

BackgroundSmall laboratory fish share many anatomical and histological characteristics with other vertebrates, yet can be maintained in large numbers at low cost for lifetime studies....Full Text Available

93

Massive encapsulation of larval Anguillicoloides crassus in the intestinal wall of Japanese eels  

UK PubMed Central (United Kingdom)

BackgroundWithin the last 25 years, after the introduction of the swimbladder nematode Anguillicoloides crassus from East-Asia to Europe, a body of work has aggregated...Full Text Available

94

Lack of Association Between Prokineticin 2 Gene and Japanese Methamphetamine Dependence  

UK PubMed Central (United Kingdom)

Disruption of circadian rhythms may be involved in the pathophysiology of psychiatric disorders, including drug addiction. Recently, we detected the significant association between prokineticin 2 receptor...Full Text Available

2011-03-01

95

Heterogeneous mutations in the human lipoprotein lipase gene in patients with familial lipoprotein lipase deficiency.  

UK PubMed Central (United Kingdom)

The DNA sequences were determined for the lipoprotein lipase (LPL) gene from five unrelated Japanese patients with familial LPL deficiency. The results demonstrated that all five patients are homozygotes...Full Text Available

1991-12-01

96

Genetic Association Analysis of NOS1 and Methamphetamine-Induced Psychosis Among Japanese  

UK PubMed Central (United Kingdom)

The neuronal nitric oxide synthase gene (NOS1) is located at 12q24, a susceptibility region for schizophrenia, and produces nitric oxide (NO). NO has been reported to play important...Full Text Available

2011-03-01

97

Evolution of DMY, a newly emergent male sex-determination gene of medaka fish.  

UK PubMed Central (United Kingdom)

The Japanese medaka fish Oryzias latipes has an XX/XY sex-determination system. The Y-linked sex-determination gene DMY is a duplicate of the autosomal gene DMRT1, which encodes a DM-domain-containing...Full Text Available

2004-04-01

98

EPA Utility FGD (Flue Gas Desulfurization) Survey.  

Science.gov (United States)

The report, generated by a computerized data base system, presents a survey of operational and planned domestic utility flue gas desulfurization (FGD) systems, operational domestic particle scrubbers, and Japanese coal-fired utility FGD installations. It ...

1981-01-01

99

Disruption of Circulation by Ethanol Promotes Fetal Alcohol Spectrum Disorder (FASD) in Medaka (Oryzias latipes) Embryogenesis  

UK PubMed Central (United Kingdom)

Japanese medaka (Oryzias latipes) embryos exposed to ethanol have developed craniofacial, cardiovascular and skeletal defects which can be compared with the phenotypic features...Full Text Available

2008-09-01

100

Dietary patterns associated with fall-related fracture in elderly Japanese: a population based prospective study  

UK PubMed Central (United Kingdom)

BackgroundDiet is considered an important factor for bone health, but is composed of a wide variety of foods containing complex combinations of nutrients. Therefore we investigated...Full Text Available

102

Basic research on technology for the solvent treatment of coal - coal liquefaction research in the framework of the Sunshine Project  

Energy Technology Data Exchange (ETDEWEB)

This article outlines research and progress into the liquefaction of coal by solvent treatment, being conducted at the National Research Institute for Pollution and Resources, Japan. (In Japanese)

1980-01-01

103

Association Analysis of Nuclear Receptor Rev-erb Alpha Gene (NR1D1) and Japanese Methamphetamine Dependence  

UK PubMed Central (United Kingdom)

Several investigations suggested abnormalities in circadian rhythms are related to the pathophysiology of psychiatric disorders, including drug addiction. Recently, orphan nuclear receptor rev-erb alpha...Full Text Available

2011-03-01

104

The effect of blending of different types of coal on the hydrogenation under high pressure. 1. The application of red mud-sulphur catalysts  

Energy Technology Data Exchange (ETDEWEB)

An investigation of the effect of blending of two different coals in various ratios on the hydrogenation reaction was carried out using a red mud-sulphur catalyst. Three Japanese coals and an Australian brown coal were used in the study. The conversion of the blended coals was compared with that obtained with each of the coals alone. A blend of the Yallourn brown coal and Shin-Yubari coal showed a synergism: it is considered that hydroaromatics from the Japanese coal promote the hydrogenation of the Yallourn coal. (The tables and captions in this paper are in English).

1983-11-01

105

Study of Japanese electrodynamic-suspension maglev systems  

Energy Technology Data Exchange (ETDEWEB)

This report presents the results of a study of the Japanese MLU magnetic-levitation (maglev) system. The development of the MLU system is reviewed, and the dynamic circuit model then is introduced and applied to the figure-eight-shaped null-flux coil suspension system. Three different types of figure-eight-shaped null-flux suspension systems are discussed in detail: (1) the figure-eight-shaped null-flux coil suspension system without cross-connection; (2) the combined suspension and guidance system; and (3) the combined propulsion, levitation, and guidance system. The electrodynamic-suspension maglev systems developed in Japan seem to be very promising and could result in a commercial application in the near future.

1994-04-01

106

Japanese R&D on new cast alloys and materials  

Energy Technology Data Exchange (ETDEWEB)

On the basis of observations of the JTEC team, it appears that Japanese universities and research institutes are leading long-term R&D thrusts for development of new materials casting technologies. Significant efforts include amorphous metals, intermetallics, application of MHD in continuous casting of steel, and energy efficient furnace technology. Industrial R&D seems focused more on process improvements than on new product technologies, but significant efforts in new cast materials included cast metal matrix composites, materials substitutions for thinner wall products, and advanced ceramic products for foundry industry applications.

1996-05-01

107

Technical note: A physical phantom for assessment of accuracy of deformable alignment algorithms  

International Nuclear Information System (INIS)

The purpose of this study was to investigate the feasibility of a simple deformable phantom as a QA tool for testing and validation of deformable image registration algorithms. A diagnostic thoracic imaging phantom with a deformable foam insert was used in this study. Small plastic markers were distributed through the foam to create a lattice with a measurable deformation as the ground truth data for all comparisons. The foam was compressed in the superior-inferior direction using a one-dimensional drive stage pushing a flat 'diaphragm' to create deformations similar to those from inhale and exhale states. Images were acquired at different compressions of the foam and the location of every marker was manually identified on each image volume to establish a known deformation field with a known accuracy. The markers were removed digitally from corresponding images prior to registration. Different image registration algorithms were tested using ...

2007-07-01

108

PHARMACOLOGICAL TREATMENTS FOR TINNITUS: NEW AND OLD  

UK PubMed Central (United Kingdom)

Subjective tinnitus, the phantom ringing or buzzing sensation that occurs in the absence of sound, affects 12–14% of adults; in some cases the tinnitus is so severe or disabling that...Full Text Available

2009-01-01

109

Monte Carlo modeling of 60Co HDR brachytherapy source in water and in different solid water phantom materials  

UK PubMed Central (United Kingdom)

The reference medium for brachytherapy dose measurements is water. Accuracy of dose measurements of brachytherapy sources is critically dependent on precise measurement of the source–detector...Full Text Available

2010-01-01

110

Intelligent Motion and Interaction Within Virtual Environments  

Science.gov (United States)

Typical aircraft types supported include F4-Phantom, Tornado, MiG-29 ...... attempt to develop a theoretical explanation for learning phenomena [16]. ..... perspective, a primary reason for this is that an exponential curve approximates ...

111

Computed radiography in X-ray examination of stomach. Evaluation by phantom experiments and clinical studies  

Energy Technology Data Exchange (ETDEWEB)

The usefulness and clinical applicability of computed radiography(FCR) in X-ray examination of the stomach were evaluated in comparison with film-screen (FS) radiography by both phantom experiments and clinical studies. Receiver operating characteristic (ROC) curve analysis consisting of 25 normal and 25 artificially created simulated lesions on an orginally created Styrofoam phantom showed no difference in lesion detectability between FCR and FS radiography. Both were also equal in evaluation of the internal structure and margin of the 25 lesions by visual ranking. ROC curve analysis of clinical cases was performed in 30 cases, 20 normal and 10 abnormal, while evaluation by visual ranking was performed on 18 lesions. There was no significant difference between FCR and FS radiography either with ROC curve analysis or visual ranking, although the variations were somewhat greater in the clinical cases than in the phantom ...

1995-08-01

112

Computed radiography in X-ray examination of stomach. Evaluation by phantom experiments and clinical studies  

International Nuclear Information System (INIS)

The usefulness and clinical applicability of computed radiography(FCR) in X-ray examination of the stomach were evaluated in comparison with film-screen (FS) radiography by both phantom experiments and clinical studies. Receiver operating characteristic (ROC) curve analysis consisting of 25 normal and 25 artificially created simulated lesions on an orginally created Styrofoam phantom showed no difference in lesion detectability between FCR and FS radiography. Both were also equal in evaluation of the internal structure and margin of the 25 lesions by visual ranking. ROC curve analysis of clinical cases was performed in 30 cases, 20 normal and 10 abnormal, while evaluation by visual ranking was performed on 18 lesions. There was no significant difference between FCR and FS radiography either with ROC curve analysis or visual ranking, although the variations were somewhat greater in the clinical cases than in the phantom ...

1995-01-01

113

A convolution/superposition method using primary and scatter dose kernels formed for energy bins of X-ray spectra reconstructed as a function of off-axis distance: comparison of calculated and measured 10-MV X-ray doses in thorax-like phantoms  

British Library Electronic Table of Contents (United Kingdom)

We performed experimental studies on the convolution/superposition method reported in the former companion paper (Iwasaki in Radiol Phys Technol 4, 2011) using 10-MV X-ray beams from open-jaw-collimated fields. The method uses primary and scatter dose kernels formed for energy bins of X-ray spectra reconstructed as a function of off-axis distance. We made a comparison of calculations and measurements in water phantoms and thorax-like phantoms with respect to percentage depth dose curves, tissue???phantom ratio curves, and dose profiles. We made the dose calculation by taking into account the beam-hardening effect with depth and the off-axis radiation-softening effect. We found that the method could be used, in general, for performing accurate dose calculations.

2011-01-01

114

Semi-automated segmentation of the sigmoid and descending colon for radiotherapy planning using the fast marching method  

International Nuclear Information System (INIS)

A fast and accurate segmentation of organs at risk, such as the healthy colon, would be of benefit for planning of radiotherapy, in particular in an adaptive scenario. For the treatment of pelvic tumours, a great challenge is the segmentation of the most adjacent and sensitive parts of the gastrointestinal tract, the sigmoid and descending colon. We propose a semi-automated method to segment these bowel parts using the fast marching (FM) method. Standard 3D computed tomography (CT) image data obtained from routine radiotherapy planning were used. Our pre-processing steps distinguish the intestine, muscles and air from connective tissue. The core part of our method separates the sigmoid and descending colon from the muscles and other segments of the intestine. This is done by utilizing the ability of the FM method to compute a specified minimal energy functional integrated along a path, and thereby extracting the colon centre line between user-defined control points in the sigmoid and ...

2010-09-21

115

Development of a geometrically accurate imaging protocol at 3 Tesla MRI for stereotactic radiosurgery treatment planning  

International Nuclear Information System (INIS)

The purpose of this study is to develop a geometrically accurate imaging protocol at 3 T magnetic resonance imaging (MRI) for stereotactic radiosurgery (SRS) treatment planning. In order to achieve this purpose, a methodology is developed to investigate the geometric accuracy and stability of 3 T MRI for SRS in phantom and patient evaluations. Forty patients were enrolled on a prospective clinical trial. After frame placement prior to SRS, each patient underwent 3 T MRI after 1.5 T MRI and CT. MR imaging protocols included a T1-weighted gradient echo sequence and a T2-weighted spin echo sequence. Phantom imaging was performed on 3 T prior to patient imaging using the same set-up and imaging protocols. Geometric accuracy in patients and phantoms yielded comparable results for external fiducial reference deviations and internal landmarks between 3 T and 1.5 T MRI (mean ?0.6 mm; standard deviation ?0.3 mm). Mean stereotactic ...

2010-11-21

116

Correlation between bone mineral density and body composition in Japanese females aged 18?40?years with low forearm bone mineral density  

British Library Electronic Table of Contents (United Kingdom)

Objectives To clarify the relationship between bone mineral density (BMD) and body composition in Japanese women aged 18?40?years with low forearm BMD. Methods The subjects were Japanese199 women who had been selected for inclusion in the study based on a low forearm BMD determined at the Annual Women?s Health Examination. The subjects? mean (? standard deviation) age, body height, body weight, and body mass index (BMI) were 33.5 (?4.3) years, 158.1 (?5.1) cm, 49.6 (?5.7) kg, and 19.8 (?2.1), respectively. The BMD of the lumbar spine, total body, and left arm were measured using dual-energy X-ray absorptiometry (DXA). Fat mass (FM), bone-free lean tissue mass (LTM), and body fat percentage (BF%) were measured simultaneously with DXA. Results In the structural equation model, the standardiz...

2009-01-01

117

Assimilation and Segregation of Imperial Subjects: "Educating" the Colonised during the 1910-1945 Japanese Colonial Rule of Korea  

Science.gov (United States)

This study looks at how education policies in colonial Korea changed over time in order to accommodate the needs of the colonial authorities during the period of Japanese colonial rule in Korea (1910-1945). The colonial experience can be divided into four different periods according to the four Educational Ordinances issued in 1911, 1922, 1938, and 1943 by the colonial government with each period corresponding to a historic event or context. The constitutive relevance of colonial discourse for an understanding of education can be found in the gradual transformation of the education sector in Korea under colonial rule. It is evident that Japanese colonial policy was inherently contradictory in principle and in practice. On the one hand it sought the assimilation of the Koreans, while on the other it maintained its discriminatory and exploitative practices. Such contradiction was obvious within the colonial education system. As the principal ...

2010-12-01

118

Study of spatial resolution in three-dimensional rotational angiography  

International Nuclear Information System (INIS)

In interventional radiology (IVR) of cerebral aneurysms, it is important to understand the form and physical relationships between the cerebral aneurysm and the surrounding vessels. However, because the vessels in the head area are highly complex, it can be difficult to comprehend the structure using conventional angiography. Therefore, three-dimensional rotational angiography (3D-RA) has been used in recent years. This article discusses studies of the spatial resolution of 3D-RA. We reconstructed 3D-RA of an acrylic slit phantom (slit widths: 0.5, 0.75, 1.0, 1.5 mm) and examined spatial resolution by visual evaluation and profile curves. When the slit phantom was arranged to avoid the effect of beam hardening, the spatial resolution of 3D-RA was found to be as high as 0.75 mm. When the slit phantom was placed orthogonal to the rotational axis of the C-arm, the spatial resolution of 3D-RA was decreased because of the cone ...

2006-03-01

119

Phantom and animal imaging studies using PLS synchrotron X-rays  

CERN Document Server

Ultra-high resolution radiographs can be obtained using synchrotron X-rays. A collaboration team consisting of K-JIST, POSTECH and YUMC has recently commissioned a new beamline (5C1) at Pohang Light Source (PLS) in Korea for medical applications using phase contrast radiology. Relatively simple image acquisition systems were set up on 5C1 beamline, and imaging studies were performed for resolution test patterns, mammographic phantom, and animals. Resolution test patterns and mammographic phantom images showed much better image resolution and quality with the 5C1 imaging system than the mammography system. Both fish and mouse images with 5C1 imaging system also showed much better image resolution with great details of organs and anatomy compared to those obtained with a conventional mammography system. A simple and inexpensive ultra-high resolution imaging system on 5C1 beamline was successfully implemented. The authors were able to acquire ...

2001-01-01

120

Neutron capture therapy beam on the LVR-15 reactor  

Energy Technology Data Exchange (ETDEWEB)

Several configurations of moderating and shielding materials have been designed and measured on the LVR-15 reactor for boron neutron capture therapy (BNCT) purposes. To determine the neutron and gamma ray space-energy distributions in the cylindrical geometry, the two-dimensional code DOT with the coupled neutron-gamma data library DLC-36 was used. The experimental verification of the beam parameters was performed in the LVR-15 reactor thermal column empty space with layers of graphite, aluminium, alumina, lead and bismuth. Attention was paid to establishing techniques and instrumentation for monitoring the neutron and gamma ray dose and beam quality. The thermal and epithermal flux densities were measured by activation foils, the neutron spectrum was determined with a Bonner spectrometer and gamma ray background with a scintillation spectrometer. The distribution of thermal neutrons in the human head phantom was mapped with a small semiconductor detector (Si[sup ...

1992-01-01

121

Neutron capture therapy beam on the LVR-15 reactor  

International Nuclear Information System (INIS)

Several configurations of moderating and shielding materials have been designed and measured on the LVR-15 reactor for boron neutron capture therapy (BNCT) purposes. To determine the neutron and gamma ray space-energy distributions in the cylindrical geometry, the two-dimensional code DOT with the coupled neutron-gamma data library DLC-36 was used. The experimental verification of the beam parameters was performed in the LVR-15 reactor thermal column empty space with layers of graphite, aluminium, alumina, lead and bismuth. Attention was paid to establishing techniques and instrumentation for monitoring the neutron and gamma ray dose and beam quality. The thermal and epithermal flux densities were measured by activation foils, the neutron spectrum was determined with a Bonner spectrometer and gamma ray background with a scintillation spectrometer. The distribution of thermal neutrons in the human head phantom was mapped with a small semiconductor detector (Si"6Li). ...

1991-10-01

122

Willingness to pay for green electricity in Japan as estimated through contingent valuation method  

Energy Technology Data Exchange (ETDEWEB)

Renewable energy systems, such as photovoltaic and wind-turbine energy systems, are considered to be environmentally sound from the viewpoint of carbon-dioxide emissions and resource depletion. The cost of energy supplied from renewable energy systems is higher than that of conventional fossil-fuel systems, and this hinders the wider spread of renewable energy systems. Global environmental problems, however, are becoming more obvious. There is a movement to defray the additional cost of electricity generated in environmentally-sound processes. In this paper, we report the results of a survey using the contingent valuation method (CVM) of the willingness of Japanese households to pay more, in the form of a flat monthly surcharge, for renewable energy. The median value of willingness to pay for renewable energy by Japanese households is estimated at about 2000 yen (around 17 US$ with the exchange rate 115 yen/US$) per month per household. ...

2004-08-01

123

The present status of the Japanese steel industry and our expectations for Canadian coal  

Energy Technology Data Exchange (ETDEWEB)

The current status and prospects for Japan`s economy and steel industry, forecast for demand and supply of coking coal, directions in steel making technology, and Japan`s expectations for Canadian coal are discussed. The PCI system, the Coal Moisture Control System (CMC) to increase coke density before it is fed into coke ovens, a feeder that allows use of lower quality coke on the outskirts of blast furnaces, the Direct Iron Ore Smelting (DIOS) Process, and the `Next Generation Coke Oven`, where coke is heated rapidly and coked at 700-800{degree}C are considered. By 2000, semi-soft coking coals are expected to account for over half of total coal consumption by Japanese steel mills.

1995-09-01

124

Reliability and validity of the PedsQL? Multidimensional Fatigue Scale in Japan  

British Library Electronic Table of Contents (United Kingdom)

Purpose To examine the reliability and validity of the Japanese-language version of the PedsQL? Multidimensional Fatigue Scale and to investigate the agreement between child self-reported fatigue and parent proxy-reported fatigue. Methods The Japanese-language version of the PedsQL? Multidimensional Fatigue Scale was administered to 652 preschoolers and schoolchildren aged 5?12 and their parents, and to 91 parents of preschool children aged 1?4. Results Internal consistency reliability was 0.62?0.87 for children and 0.81?0.93 for parents. Known-group validity was examined between a group of healthy samples (n?=?530) and chronic condition sample (n?=?102); the chronically ill group reported a significantly higher perceived fatigue problem. Correlations between child self- and parent proxy r...

2011-01-01

125

Quantitative easing works: Lessons from the unique experience in Japan 2001-2006  

British Library Electronic Table of Contents (United Kingdom)

Abstract: The current financial crisis has now led most major central banks to rely on quantitative easing. The unique Japanese experience of quantitative easing is the only experience which enables us to judge this therapy's effectiveness and the timing of the exit strategy. In this paper, we provide a new empirical framework to examine the effectiveness of Japanese monetary policy during the ''lost'' decade and quantify the effect of quantitative easing on Japan's activity and prices. We combine advantages of Markov-switching VAR methodology with those of factor analysis to establish two major findings. First, we show that the decisive change in regime occurred in two steps: it crept out from late 1995 and established itself durably in February 1999. Second, we show for the first time th...

2011-01-01

126

Nationwide surveillance of bacterial respiratory pathogens conducted by the Japanese Society of Chemotherapy in 2008: general view of the pathogens? antibacterial susceptibility  

British Library Electronic Table of Contents (United Kingdom)

For the purpose of nationwide surveillance of the antimicrobial susceptibility of bacterial respiratory pathogens collected from patients in Japan, the Japanese Society of Chemotherapy conducted a third year of nationwide surveillance during the period from January to April 2008. A total of 1,097 strains were collected from clinical specimens obtained from well-diagnosed adult patients with respiratory tract infections. Susceptibility testing was evaluable with 987 strains (189 Staphylococcus aureus, 211 Streptococcus pneumoniae, 6 Streptococcus pyogenes, 187 Haemophilus influenzae, 106 Moraxella catarrhalis, 126 Klebsiella pneumoniae, and 162 Pseudomonas aeruginosa). A total of 44 antibacterial agents, including 26 ?-lactams (four penicillins, three penicillins in combination with ?-lacta...

2011-01-01

127

Molecular identification of blood source animals from black flies (Diptera: Simuliidae) collected in the alpine regions of Japan  

British Library Electronic Table of Contents (United Kingdom)

One of vector-borne avian protozoa, Leucocytozoon lovati, has been found in the Japanese rock ptarmigans (Lagopus mutus japonicus), the endangered bird species distributed in the alpine regions in Japan. Vector arthropod species of L. lovati has also been estimated as Simuliidae black flies distributed in the same habitat of the host bird, however, possible blood meals of the black flies were not identified yet. To reveal host animals of black flies, we estimated the blood resources by using molecular techniques. Black flies were collected at Mt. Chogatake, one of the alpine regions of Japan in which Japanese rock ptarmigans live in June 2005. The analyzed 144 specimens were morphologically identified into five species including Simulium japonicum (n?=?87), Prosimulium hirtipes (n?=?48), P...

2010-01-01

128

Loss of coolant accident analysis (thermal hydraulic analysis) - Japanese industries experience  

International Nuclear Information System (INIS)

An overview of LOCA analysis in Japanese industry is presented. The BASH-M code, developed for large scale LOCA reflooding analysis, is given as an example of verification and improvement of US computer programs are given. The code's application to the operational safety analysis concerns the following main areas: 1D drift flux model base computer program CANAC; CANAC-based advanced training simulator; emergency operating procedures. The author considers also the code application to the following new PWR safety design concepts: use of steam generators for decay heat removal at LOCA conditions; use of horizontal type steam generator for maintaining two-phase natural circulation under the reactor coolant system submerged. 9 figs.

1995-11-07

129

Estimation of "1"3"7Cs body burden in Japanese, 2  

International Nuclear Information System (INIS)

The biological half-life of "1"3"7Cs in the total body of human subjects was determined in 23 individuals of Japanese male adult in their normal works by measuring amount of "1"3"7Cs in both their total body and daily urine in the same period. For the group, the value was determined by averaging the half-lives for individuals, by comparing the mean body burden and the mean daily urinary excretion, or by applying a curve fitting method to the body burden estimate. The biological half-life averaged 86 days, ranging from 50 to 161 days. The averages of the biological half-lives for the group were 83, 87 and 82 days in the different periods of observation. By the curve fitting method, 85 days was found for the group. The biological half-life for the individuals depended on both body weight and age, to a lesser extent, of the subjects. (author).

130

Efficacy, tolerability, and safety of risedronate in Japanese patients with Paget?s disease of bone  

British Library Electronic Table of Contents (United Kingdom)

This study evaluated the clinical efficacy of treatment with oral risedronate (17.5?mg once daily) for 8?weeks in 11 Japanese patients with Paget?s disease of bone (PDB). Risedronate suppressed the excessive bone turnover associated with PDB and improved several biochemical markers, including serum alkaline phosphatase (ALP), serum bone-specific ALP (BALP), urinary deoxypyridinoline (DPD), and urinary cross-linked N-telopeptide of type 1 collagen (NTX). These markers began to decrease within about 2?weeks after the initiation of treatment in most patients, and the response persisted for up to 40?weeks after the cessation of treatment. Risedronate reduced pain by week 24 in most patients. According to quantitative bone scintigraphy, the lesion with the highest radioisotope (RI) uptake showe...

2010-01-01

131

Amino acid substitutions in inherited albumin variants from Amerindian and Japanese populations  

International Nuclear Information System (INIS)

The authors report an effort to determine the basis for the altered migration of seven inherited albumin variants detected by one-dimensional electrophoresis in population surveys involving tribal Amerindians and Japanese children. An amino acid substitution has thus far been determined for four of the variants. The randomness in the albumin polypeptide of these and the other sixteen independently ascertained amino acid substitutions of albumin and proalbumin thus far established was analyzed; the clustering of eight of these at two positions in the six-amino acid propeptide sequence seems noteworthy. By comparison with other proteins studied by electrophoresis, albumin exhibits average variability. It is a paradox that individuals who, for genetic reasons, lack albumin exhibit no obvious ill effects; yet, electrophoretic variants of albumin are no more numerous than are variants of proteins, the absence of which results in severe disease.

132

Monte Carlo code comparisons for the calculation of absorbed dose per unit fluence in slab phantoms for electron energies from 50 keV to 10 MeV  

International Nuclear Information System (INIS)

The MCNPE-BO and MCNP4 Monte Carlo electron-photon codes were used to calculate the dose equivalent per unit fluence at various depths in tissue-equivalent slab phantoms for broad parallel beams of monoenergetic electrons with energies from 50 keV to 10 MeV. The study was carried out in the framework of the activities of a ICRP/ICRU Joint Task Group with the support of EURADOS WG4 (Numerical Dosimetry). Some preliminary results and comparisons as well as a general discussion on the performances of the codes are presented, demonstrating quite a satisfactory agreement among the results obtained using the two codes and those of other authors. (author).

133

Dosimetric evaluation of multi-pattern spatially fractionated radiation therapy using a multi-leaf collimator and collapsed cone convolution superposition dose calculation algorithm  

British Library Electronic Table of Contents (United Kingdom)

Purpose: In this paper, we present an alternative to the originally proposed technique for the delivery of spatially fractionated radiation therapy (GRID) using multi-leaf collimator (MLC) shaped fields. We employ the MLC to deliver various pattern GRID treatments to large solid tumors and dosimetrically characterize the GRID fields. Methods and materials: The GRID fields were created with different open to blocked area ratios and with variable separation between the openings using a MLC. GRID designs were introduced into the Pinnacle3 treatment planning system, and the dose was calculated in a water phantom. Ionization chamber and film measurements using both Kodak EDR2 and Gafchromic EBT film were performed in a SolidWater phantom to determine the relative output of each GRID design as w...

2009-01-01

134

Comparison of fluid-dynamic modeling of flow with velocity-encoded MR imaging  

International Nuclear Information System (INIS)

This paper develops a fluid dynamic model using finite difference methods characterizing flow in phantoms simulating in vivo conditions and to compare those results with velocity encoded MR images. The phantom consisted of 1-inch (2.5-cm) tubing with semicircular insert and fluid with viscosity, T1, and T2 comparable to blood. Numeric solutions to Navier-Stokes equations for this system were obtained using finite difference methods, with velocity input function of zero at walls and parabolic at both ends. In resulting color raster (CR) images, color temperature represented velocity value. In velocity-encoded MR images acquired under the same flow conditions, phase is proportional to average velocity during application of flow-encoding gradients. Because these gradients are applied along one direction per acquisition, magnitude and direction of velocity are obtained.

1990-11-25

135

Slimholes for geothermal reservoir evaluation - An overview  

Energy Technology Data Exchange (ETDEWEB)

The topics covered in this session include: slimhole testing and data acquisition, theoretical and numerical models for slimholes, and an overview of the analysis of slimhole data acquired by the Japanese. The fundamental issues discussed are concerned with assessing the efficacy of slimhole testing for the evaluation of geothermal reservoirs. the term reservoir evaluation is here taken to mean the assessment of the potential of the geothermal reservoir for the profitable production of electrical power. As an introduction to the subsequent presentations and discussions, a brief summary of the more important aspects of the use of slimholes in reservoir evaluation is given.

1996-08-01

136

Metastatic Small Bowel Tumor from Descending Colon Cancer with Extensive Hematogenous or Lymphogenous Spread: Survey of the Japanese Literature  

UK PubMed Central (United Kingdom)

We present the case of a 68-year-old female patient who was diagnosed with cancer of the descending colon in July 1994 and underwent partial resection of the colon (type 2, moderately to well differentiated...Full Text Available

137

Lee Oral History, January 16, 2008 - Johnson Space Center  

Science.gov (United States)

Jan 16, 2008 ... home town, and awards, as well as the ground personnel. .... I was also awarded six air medals, which were given based on the number of missions ..... We took these projects from birth to grave. .... Japanese sonar on their submarine. About that time another airplane dropped a bomb ...

138

Japan: Toshiba in talks to buy Westinghouse stake: report  

Wastenet

... Westinghouse Electric is already majority owned by Toshiba Corp the maker of flash memory chips, laptops, nuclear reactors and rice cookers and Shaw Group. A deal could erase any U.S. ownership of Westinghouse, the Wall Street Journal said. Shaw partnered with Toshiba, and another Japanese company to buy Westinghouse from British Nuclear Fuels PLC for $5.4 billion five years ago, the paper ...

139

Fuel-related advances in science and technology. (XIII) University education. (5) Petrochemistry and coal liquefaction  

Energy Technology Data Exchange (ETDEWEB)

The author draws the connections between the work he has done over the last ten years and related research. Connections with industry are also mentioned, and future prospects are considered. Topics discussed include research into the synthesis of olefins and into liquid phase oxidation, the catalytic effects of transition metal compounds, and coal liquefaction. (35 refs.) (In Japanese)

1982-01-01

140

Extended-Spectrum-?-Lactamase-Producing Escherichia coli Strains Isolated from Farm Animals from 1999 to 2002: Report from the Japanese Veterinary Antimicrobial Resistance Monitoring Program  

UK PubMed Central (United Kingdom)

A nationwide surveillance for antimicrobial susceptibility in Escherichia coli strains isolated from food-producing animals in Japan was conducted from 1999 to 2002. Eighteen cefazolin-resistant...Full Text Available

2005-08-01

141

Analysis of energy demand, and evaluation of energy conservation measures in urban districts  

International Nuclear Information System (INIS)

Mitsubishi Research Institute has analyzed the energy demand of a typical Japanese city, Yokohama, as well as the distribution of fossil-energy flow, and the final consumption by sectors. It has evaluated the effectiveness of various energy conservation measures, (e.g., cogeneration, electric cars, insulation,...) in countering the global warming trend. This study defines a viable methodology which may be utilized, in the future, in examining the effectiveness of environmental policies. (TEC). 1 tab., 4 figs.

142

The different structural scales of the breast and their impact on time-of-flight and diffraction tomography  

Energy Technology Data Exchange (ETDEWEB)

Ultrasound tomography is an attractive imaging method for the detection of breast cancer. The complex anatomy of the breast with its different spatial scales and material property contrasts make accurate reconstructions very challenging. This paper proposes a hybrid approach whereby Travel-of-Flight and Diffraction Tomography are combined together to achieve high-resolution and high-accuracy sound-speed reconstructions. The method is validated with several numerical phantoms.

2010-01-01

143

IMRT verification by three-dimensional dose reconstruction from portal beam measurements  

International Nuclear Information System (INIS)

A method of reconstructing three-dimensional, in vivo dose distributions delivered by intensity-modulated radiotherapy (IMRT) is presented. A proof-of-principle experiment is described where an inverse-planned IMRT treatment is delivered to an anthropomorphic phantom. The exact position of the phantom at the time of treatment is measured by acquiring megavoltage CT data with the treatment beam and a research prototype, flat-panel, electronic portal imaging device. Immediately following CT imaging, the planned IMRT beams are delivered using the multiple-static field technique. The delivered fluence is sampled using the same detector as for the CT data. The signal measured by the portal imaging device is converted to primary fluence using an iterative phantom-scatter estimation technique. This primary fluence is back-projected through the previously acquired megavoltage CT model of the phantom, with ...

2002-08-01

144

Further means for reducing radiation dose during exposure of the pelvis in infants  

International Nuclear Information System (INIS)

A simple dose-saving procedure for the diagnosis of congenital hip dysplasia employing a diaphragm in nearfocus position is presented. Doses to the skin and the gonads were measured with a phantom for the new and other techniques. With optimal techniques the skin dose is smaller than 2 mR and the gonadal doses lie around 0.1 mR for both male and female patients. An estimate of the dose burden from undesired radiation is appended. (orig.).

145

Evaluation of calcification in pulmonary nodules using bone images obtained with single exposure energy subtraction  

Energy Technology Data Exchange (ETDEWEB)

Bone images obtained by single exposure dual energy subtraction with computed radiography, a new image processing method, were evaluated for the detectability of calcification in lung nodules in both phantom and clinical studies. In the phantom study, five simulated nodules containing known and uniformly distributed amounts of calcium hydroxide were placed in a human chest phantom and images were obtained the following five techniques: (1) conventional radiography (CXR), (2) low kV conventional radiography (Low), (3) Fuji computed radiography (FCR), (4) bone images with conventional singles exposure energy subtraction (ES) and (5) bone image with fine single exposure energy subtraction (FES). The detectability of calcification in the simulated nodules was evaluated by six radiologists using ROC analysis and two-way analysis of variance. In the clinical study, images of 42 lung nodules (21 calcified lung nodules and 21 ...

1995-08-01

146

Evaluation of calcification in pulmonary nodules using bone images obtained with single exposure energy subtraction  

International Nuclear Information System (INIS)

Bone images obtained by single exposure dual energy subtraction with computed radiography, a new image processing method, were evaluated for the detectability of calcification in lung nodules in both phantom and clinical studies. In the phantom study, five simulated nodules containing known and uniformly distributed amounts of calcium hydroxide were placed in a human chest phantom and images were obtained the following five techniques: 1) conventional radiography (CXR), 2) low kV conventional radiography (Low), 3) Fuji computed radiography (FCR), 4) bone images with conventional singles exposure energy subtraction (ES) and 5) bone image with fine single exposure energy subtraction (FES). The detectability of calcification in the simulated nodules was evaluated by six radiologists using ROC analysis and two-way analysis of variance. In the clinical study, images of 42 lung nodules (21 calcified lung nodules and 21 ...

1995-01-01

147

A novel method to characterize the MTF in 3D for computed mammotomography  

Science.gov (United States)

A novel phantom has been developed to measure the modulation transfer function (MTF) in 3D for x-ray computed tomography. The phantom consists of three tungsten wires, positioned nearly orthogonal to each other. Simultaneous measurements of the MTF are taken at various locations along the three orthogonal reconstructed planes. Our computed mammotomography (CmT) system uses a Varian Paxscan 2520 digital x-ray detector which can be positioned anywhere in ~2pi steradian band and can have arbitrary trajectories. With a half-cone beam geometry and with the phantom positioned near the center of rotation, projection images are acquired over 360 degrees. Various 3D orbits are evaluated including vertical axis of rotation and saddle. Reconstructions were performed using an iterative ordered-subsets transmission algorithm on rebinned projection images, using various numbers of iterations. Rotation of reconstructed slices isolated ...

2006-03-01

148

A comparison of cathode ray tube (CRT) and computed radiography (CR) diagnosis in mammography  

International Nuclear Information System (INIS)

Quantitative evaluation of CRT and CR observations in indentification of malignancy using phantom and clinical data. A breast phantom and a total of 40 patients were imaged by Fuji computed radiography (FCR). The images were interpreted twice by six radiologists both on CR film (2510 x 2000 pixels x 10 bits, 0.1 mm spatial resolution) and on a CRT monitor (1568 x 1152 pixels x 10 bits, 0.1 mm pixel size with double expansion) with image processing parameters of a toutine (RN 1.0, RE 0.2), for a calcification (RN 9.0, RE 4.0) and for a mass (RN 7.0, RE 2.0). The forty clinical cases included breast diseases with calcifications, masses, and normal breasts. Two-tailed t-test was performed to analyze interpretation of simulated microcalcifications and masses in the phantom. The receiver operating characteristic (ROC) analysis was performed to evaluate clinical cases. In all interpretation studies using both breast ...

1999-11-01

149

Prediction of transmitted portal dose for in-vivo dosimetry by a superposition-convolution planning system  

International Nuclear Information System (INIS)

Full text: Verification of the dose delivered to a patient during radiotherapy is an important quality assurance procedure, however this is rarely performed due to the extra time involved. Electronic portal images (EPIs) are currently acquired at many centres during radiotherapy treatment for positioning verification. These could be utilised for dose verification provided 1) an accurate prediction of the dose transmitted through the patient to the EPID can be produced for the patients' radiotherapy beams, and, 2) the EPID image can be converted to an accurate measured dose. Ideally, the radiotherapy planning system (RTPS) would be used to produce the predicted dose as part of the planning procedure. The aim of this project is to investigate whether the convolution-superposition model of the Pinnacle RTPS can accurately calculate dose transmitted through a patient and deposited in a phantom at a large source to surface distance. The dose transmitted through a ...

2004-12-01

150

The forming process of magnesium alloy for Japanese home electric components  

Energy Technology Data Exchange (ETDEWEB)

Magnesium alloys have replaced resins as a material for the components of electronic products such as cell phone and notebook personal computer mainly, because of their lightness and rigidity. Thin walls, a complicated shape, and high appearance quality are all needed in the external parts. Die-casting and injection molding are the main method of manufacturing magnesium alloy parts. The optimal cast conditions and mold design have been investigated in order that a few defects such as surface cracks and mold cavities in casting parts would be reduced. Instead of cast, plastic forming technologies such as warm drawing and hot forging have been developed to form thinner walls and less defects. Plastic formability of magnesium alloy in hot working is dependent on a grain size of material. The material with fine grains has advantage of being formed at high strain rate. The characteristics of forming processes of magnesium parts for Japanese home electric appliances are ...

2005-07-01

151

Radioiodination of chicken luteinizing hormone without affecting receptor binding potency  

Energy Technology Data Exchange (ETDEWEB)

By improving the currently used lactoperoxidase method, we were able to obtain radioiodinated chicken luteinizing hormone (LH) that shows high specific binding and low nonspecific binding to a crude plasma membrane fraction of testicular cells of the domestic fowl and the Japanese quail, and to the ovarian granulosa cells of the Japanese quail. The change we made from the original method consisted of (1) using chicken LH for radioiodination that was not only highly purified but also retained a high receptor binding potency; (2) controlling the level of incorporation of radioiodine into chicken LH molecules by employing a short reaction time and low temperature; and (3) fractionating radioiodinated chicken LH further by gel filtration using high-performance liquid chromatography. Specific radioactivity of the final {sup 125}I-labeled chicken LH preparation was 14 microCi/micrograms. When specific binding was 12-16%, nonspecific binding was as ...

1989-12-01

152

Introduction of energy saving type air conditioner  

Energy Technology Data Exchange (ETDEWEB)

It is reported that due to the large demand for electricity in Japanese homes and given the fact that the energy consumption rate of air conditioners to the total energy consumption rate in an average home exceeds 20%, an energy saving-type room air conditioner is essential, also for environmental reasons. Japanese customers ranked high running costs as a major drawback of conventional equipment. Toshiba started developing the first generation energy saving air conditioners in 1993. Improvements to the concept were made and the 1995 model offers a heating COP of 4.65 and a cooling COP of 4.3 at rated conditions, an improvement of more than 30% compared to the conventional model. Various component improvements have led to this high performance including the indoor fan design, a DC compressor motor and inverter using digital sampling, advanced (PMV) control technology, and compact heat exchangers. The latest feature is genetic algorithm control. ...

1996-07-01

153

Geochemical study on origin of natural gases in Japanese oil and gas fields  

Energy Technology Data Exchange (ETDEWEB)

The origin of natural gas in the Japanese oil and gas fields are geochemically studied. Samples are taken from structural natural gas, surface gas seepage, water-dissolved natural gas and coal-field gas of the Japan Sea coast area. The origins of primary hydrocarbons are classified into bacteria gas and thermogenic gas, the latter being subclassified into gas in oil production zone with the per million deviation of the carbon isotope (/sup 13/C/sup 1/) of methane less than -35 and those gases with maturity higher than this. Surface gas seepage is subjected to migration and bacterial oxidation. Coal gas is similar to oil gas. The CO/sub 2/ concentration is 0 - 2% and /sup 13/CO/sub 2/ deviations from -30 - +30. The origin can be barely estimated from the isotopic composition because of the wide secondary change in the composition. The origin and migration of gas from the gas field of northern Niigata are not similar to those in the southern area, which consist of a ...

1988-05-01

154

Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii, and California: demographic, physical, dietary, and biochemical characteristics  

International Nuclear Information System (INIS)

These summary descriptive data of ethnically similar cohorts of indigenous and migrant Japanese males have shown similarities or slight differences in characteristics wholly or largely genetically determined, such as blood groups, stature, and skeletal size. Differences have been noted in characteristics largely environmental or behavioral, such as diet and cigarette smoking habit, as well as in characteristics determined by a varying mixture of genetic and environmental influences, such as weight, blood pressure, glucose tolerance, and serum lipid and uric acid levels. Detailed analyses of the distributions of laboratory variables, of dietary data obtained by different methods, and of correlations among laboratory, dietary, physical, and demographic variables are currently in progress. Also part of the study plan are determinations of disease prevalence from evaluation of examination, laboratory, and electrocardiographic findings, of disease incidence from repeat ...

155

Characteristic findings of pediatric inpatients with pandemic (H1N1) 2009 virus infection among severe and nonsevere illnesses  

British Library Electronic Table of Contents (United Kingdom)

We analyzed the clinical features of inpatients at a Japanese pediatric department who were infected with pandemic (H1N1) 2009 virus. Study participants included 46 children hospitalized from July 2009 to January 2010. Infection with the virus was confirmed using real-time reverse transcriptase polymerase chain reaction (RT-PCR). The epidemic month was October 2009; 34 patients were boys, and median age was 7?years. Pandemic influenza-associated respiratory diseases included pneumonia (n?=?42), bronchitis (n?=?3), and pharyngitis (n?=?1). The median time from onset to admission was 3?days. Children were divided into those with severe (n?=?32) versus nonsevere illnesses (n?=?14) according to Japanese guidelines. Significant features in the severe group were younger age, previous asthmatic a...

2011-01-01

156

An evaluation of corrosion resistant alloys by field corrosion test in Japanese refuse incineration plants  

Energy Technology Data Exchange (ETDEWEB)

As the first step for development of the corrosion resistant superheater tube materials of 500 C, 100 ata used in high efficient waste-to-energy plants, field corrosion tests of six conventional alloys were carried out at metal temperatures of 450 C and 550 C for 700 and 3,000 hours in four typical Japanese waste incineration plants. The test results indicate that austenitic alloys containing approximately 80 wt% [Cr+Ni] show excellent corrosion resistance. When the corrosive environment is severe, intergranular corrosion of 40{approximately}200 {micro}m depth occurs in stainless steel and high alloyed materials. It is confirmed quantitatively that corrosion behavior is influenced by environmental corrosion factors such as Cl concentration and thickness of deposits on tube surface, metal temperature, and flue gas temperature. The excellent corrosion resistance of high [Cr+Ni+Mo] alloys such as Alloy 625 is explained by the stability of its protective oxide, such ...

1995-12-01

157

An evaluation of corrosion resistant alloys by field corrosion test in Japanese refuse incineration plants  

International Nuclear Information System (INIS)

As the first step for development of the corrosion resistant superheater tube materials of 500 C, 100 ata used in high efficient waste-to-energy plants, field corrosion tests of six conventional alloys were carried out at metal temperatures of 450 C and 550 C for 700 and 3,000 hours in four typical Japanese waste incineration plants. The test results indicate that austenitic alloys containing approximately 80 wt% [Cr+Ni] show excellent corrosion resistance. When the corrosive environment is severe, intergranular corrosion of 40#approx#200 microm depth occurs in stainless steel and high alloyed materials. It is confirmed quantitatively that corrosion behavior is influenced by environmental corrosion factors such as Cl concentration and thickness of deposits on tube surface, metal temperature, and flue gas temperature. The excellent corrosion resistance of high [Cr+Ni+Mo] alloys such as Alloy 625 is explained by the stability of its protective oxide, such that the ...

1995-03-26

158

The joint project for high-intensity proton accelerators  

Energy Technology Data Exchange (ETDEWEB)

Japan Atomic Energy Research Institute (JAERI) and the High Energy Accelerator Research Organization (KEK) are promoting the joint project integrating both the Neutron Science Project (NSP) of JAERI and the Japan Hadron Facility Project (JHF) of KEK for comprehensive studies on basic science and technology using high-intensity proton accelerator. This document describes the joint project prepared by the Joint Project Team of JAERI and KEK to construct accelerators and research facilities necessary both for the NSP and the JHF at the site of JAERI Tokai Establishment. It was originally written in English and translated into Japanese with some corrections. (author)

2000-02-01

159

The development of a centralized automatic monitoring system for coal mines: composition and functions of the system  

Energy Technology Data Exchange (ETDEWEB)

A centralized, automatic monitoring system for coal mines has been developed. The system consists of newly-developed and improved sensors, transmission equipment, a minicomputer designed for scientific and technical calculations, and accompanying software (MOLES). MOLES performs six functions: input, computation, decision, memory, output and correction. Previously, centralized monitoring has been limited to single dimensional monitoring of the 'time and point' type. The present system carries out data analysis and processing with respect to time, space and item. It is also capable of simple automatic diagnosis of abnormalities. (In Japanese)

1983-01-01

160

Tests of effective utilization of industrially produced materials: soil engineering properties and earthworking problems of coal ash and red mud  

Energy Technology Data Exchange (ETDEWEB)

An account of problems arising in the use of coal ash and red mud as filling or banking materials. The soil engineering properties of these materials are explained. Problems encountered in on-site use include difficulty in controlling moisture content, absorption swelling and strongly alkaline atmospheres. For long-term use, it will be necessary to minimize the variations in engineering characteristics and in quality that result from the method of discharge and from the raw materials themselves. There must also be thorough quality control during shipment. (7 refs.) (In Japanese)

1982-01-01

161

Neutron activation analysis of trace elements in Japanese hormesis cosmetics  

International Nuclear Information System (INIS)

In Japan, cosmetics claiming hormesis effect are available through Internet. Although these cosmetics show the contents, they never mention the minor elements and radioactive sources. The existence of radioisotopes, however, was observed by measurements of the gamma-rays with a HPGe detector. In this study, in order to clarify the contents of trace elements, the hormesis cosmetics including radioactive sources were analyzed using INAA, PGAA and NAA with multiple gamma-ray detection (NAAMG). Nineteen elements were analyzed quantitatively in hormesis cosmetics by INAA, PGAA and NAAMG and 16 elements were detected qualitatively by SEM-EPMA. (author)

2008-12-01

162

Low-temperature technology for high-grade products from coal  

Energy Technology Data Exchange (ETDEWEB)

Gasification and hydrogenation are the two basic routes for coal processing. Accounts are given of various low-temperature processes in coal gasification route A: air separation, removal of sour gas by the Rectisol process, liquid nitrogen washing, the material balance and utility consumption of these processes, plus low-temperature gas separation, partial condensation and methane washing. There are also accounts of the low-temperature processes involved in gasification route B: i.e., in the indirect coal liquefaction and direct liquefaction carried out in the Sasol II and III processes. (3 refs.) (In Japanese)

1982-01-01

163

Evaluation test on the thermal stability of resin as neutron shielding material for spent fuel transport cask  

Energy Technology Data Exchange (ETDEWEB)

Epoxy-resin based neutron shielding material, NS-4-FR, is used for spent fuel transport and/or storage cask. In this paper the outline of thermal aging test performed to evaluate the heating effect on this neutron shielding material, NS-4-FR, is introduced. The test is consisted of two kinds of thermal aging test, one is 'Basic Test' and the other is 'Block Heating Test'. The former is cooperatively performed by ten Japanese Electrical Power Companies, and the latter is done by GESC and NOF Corporation. (authors)

1998-07-01

164

Evaluation test on the thermal stability of resin as neutron shielding material for spent fuel transport cask  

International Nuclear Information System (INIS)

Epoxy-resin based neutron shielding material, NS-4-FR, is used for spent fuel transport and/or storage cask. In this paper the outline of thermal aging test performed to evaluate the heating effect on this neutron shielding material, NS-4-FR, is introduced. The test is consisted of two kinds of thermal aging test, one is 'Basic Test' and the other is 'Block Heating Test'. The former is cooperatively performed by ten Japanese Electrical Power Companies, and the latter is done by GESC and NOF Corporation. (authors)

1998-05-10

165

Evaluation of prompt neutron spectra for americium isotopes by multimodal Madland-Nix model  

Energy Technology Data Exchange (ETDEWEB)

The prompt neutron spectra of {sup 241}Am, {sup 242m}Am, and {sup 243}Am were evaluated for the next version of Japanese Evaluated Nuclear Data Library, using the methodology developed by the authors. The method is based on the Madland-Nix theory with some improvements to consider the multimodal nature of the fission process, and shell effects on the level density parameters and the neutron multiplicity from light and heavy fragments. The results were compared with previous evaluations. (authors)

2008-07-01

166

Current situation of steel industry and coking coal industry and expectations for Canadian coal  

Energy Technology Data Exchange (ETDEWEB)

The world steel industry and market and the current status and prospects for the Japanese steel industry are discussed with particular reference to China, Europe, and the US. Trends in coking coal supply from Australia, Canada, and Mongolia and changes in demand for hard and semi-soft coking coals are considered. Canadian coal plays a significant role in the hard coking coal and PCI coal markets. This is expected to continue. Emerging concerns include the strong Canadian dollar and increases in fuel and materials costs. Canadian suppliers are asked to improve efficiencies, be competitive in the overall coal chain, and diversify their PCI coal reserves. 14 figs.

2006-07-01

167

Use of neutron and gamma ray spectral measurements and calculations to obtain dosimetric information for DT neutrons  

Energy Technology Data Exchange (ETDEWEB)

Neutron and gamma ray energy spectra were measured using an NE-213 scintillator at depths of 7.2, 15.2, and 22.2 cm in a tissue-equivalent phantom which was uniformly irradiated on one face by deuterium--tritium (DT) neutrons. Coupled neutron--gamma ray multigroup discrete-ordinates calculations were performed using semi-infinite slab geometry. These calculations were used to supplement the measured spectra below 1 MeV. Similar calculations were performed to study the perturbation in the phantom due to the detector. The measured and calculated spectra were used to determine the kerma distributions for neutrons and gamma rays at each location. The gamma radiation was determined to contribute more than 10% of the total dose at each depth. The calculated kerma also reveals that a knowledge of the gamma ray spectra below 1 MeV is desirable. Key words: neutron--gamma spectra, spectrometry, kerma distributions, coupled multigroup calculations

1983-01-01

168

Use of neutron and gamma ray spectral measurements and calculations to obtain dosimetric information for DT neutrons  

International Nuclear Information System (INIS)

Neutron and gamma ray energy spectra were measured using an NE-213 scintillator at depths of 7.2, 15.2, and 22.2 cm in a tissue-equivalent phantom which was uniformly irradiated on one face by deuterium--tritium (DT) neutrons. Coupled neutron--gamma ray multigroup discrete-ordinates calculations were performed using semi-infinite slab geometry. These calculations were used to supplement the measured spectra below 1 MeV. Similar calculations were performed to study the perturbation in the phantom due to the detector. The measured and calculated spectra were used to determine the kerma distributions for neutrons and gamma rays at each location. The gamma radiation was determined to contribute more than 10% of the total dose at each depth. The calculated kerma also reveals that a knowledge of the gamma ray spectra below 1 MeV is desirable. Key words: neutron--gamma spectra, spectrometry, kerma distributions, coupled multigroup calculations.

7871-01-01

169

The Contribution of Sympathetic Mechanisms to Postamputation Phantom and Residual Limb Pain: A Pilot Study  

British Library Electronic Table of Contents (United Kingdom)

Postamputation pain (PAP) affects over 60% of major limb amputees. One of the main challenges in treating PAP is the difficulty involved in identifying pain mechanism(s), which pertains to both residual limb pain (RLP) and phantom limb pain (PLP). In this study, sympathetic blocks were performed on 17 major limb amputees refractory to treatment, including 2 placebo-controlled blocks done for bilateral amputations. One hour postinjection, mean RLP scores at rest declined from 5.2 (SD 2.8) to 2.8 (SD 2.6) (P = .0002), and PLP decreased from 5.3 (SD 3.1) to 2.3 (SD 2.1) (P = .0009). By 1 week, mean pain scores for RLP and PLP were 4.3 (SD 2.9) and 4.2 (SD 3.0), respectively. Overall, 8 of 16 (50%) patients experienced ?50% reduction in RLP 1-hour postinjection, with the beneficial effects ...

2011-01-01

170

TLD array for precise dose measurements in stereotactic radiation techniques  

International Nuclear Information System (INIS)

We developed a new TLD array for precise dose measurement and verification of the spatial dose distribution in small radiation targets. It consists of a hemicylindrical, tissue-equivalent rod made of polystyrene with 17 parallel moulds for an exact positioning of each TLD. The spatial resolution of the TLD array was evaluated using the Leskell spherical phantom. Dose planning was performed with KULA 4.4 under stereotactic conditions on axial CT images. In the Leksell gamma unit the TLD array was irradiated with a maximal dose of 10 Gy with an unplugged 14 mm collimator. The doses delivered to the TLDs were rechecked by diode detector and film dosimetry and compared to the computer-generated dose profile. We found excellent agreement of our measured values, even at the critical penumbra decline. For the 14 mm and 18 mm collimator and for the 11 mm collimator combination we compared the measured and calculated data at full width at half maximum. This TLD array may be ...

1996-12-01

171

Radiation exposure of children in pediatric radiology. Pt. 6. Conversion factors for reconstruction of organ dose in abdominal radiography; Zur Strahlenexposition von Kindern in der paediatrischen Radiologie. T. 6. Konversionsfaktoren zur Rekonstruktion von Organdosen bei Abdomenaufnahmen  

Energy Technology Data Exchange (ETDEWEB)

Purpose: calculation of conversion coefficients for the reconstruction of organ doses from entrance doses for abdomen radiographs of 0, 1, 5, 10, 15, and 30-year-old patients in conventional pediatric radiology for the radiographic settings recommended by the German and European guidelines for quality management in diagnostic radiology. Materials und method: using the commercially available personal computer program PCXMC developed by the Finnish Center for Radiation and Nuclear Safety (Saeteilyturvakeskus STUK), conversion coefficients for conventional abdomen radiographs were calculated performing Monte Carlo simulations in mathematical hermaphrodite phantom models describing patients of different ages. The possible clinical variation of beam collimation was taken into consideration by defining optimal and suboptimal radiation fields on the phantoms' surfaces. Results: conversion coefficients for the reconstruction of organ does in ...

2009-10-15

172

Measurement of electron energy fluence spectra from electron beam therapy machines  

Energy Technology Data Exchange (ETDEWEB)

A technique capable of measuring the electron energy fluence spectra in a scattering medium was designed. These measurements were performed by setting a bremsstrahlung conversion target on the surface of a phantom, at an intermediate depth, and at a depth equal to electron mean range. The bremsstrahlung produced by the deceleration of electrons in the target was passed through an air channel in the phantom and passed forward by a pinhole collimator into a Na(Tl) detector. The measured pulse height data were unfolded to correct for the distortion of the spectrometer system by using the FORIST unfolding code. The unfolded bremsstrahlung spectra represent the electron energy fluence spectra convolution with the bremsstrahlung produced in the target. To generate the electron energy fluence spectra, the unfolded bremsstrahlung spectra were deconvoluted by using the MAZE2 unfolding code. CYLTRAN, a coupled electron-photon Monte Carlo transport code, ...

1984-01-01

173

FDTD analysis of body-core temperature elevation in children and adults for whole-body exposure  

Energy Technology Data Exchange (ETDEWEB)

The temperature elevations in anatomically based human phantoms of an adult and a 3-year-old child were calculated for radio-frequency whole-body exposure. Thermoregulation in children, however, has not yet been clarified. In the present study, we developed a computational thermal model of a child that is reasonable for simulating body-core temperature elevation. Comparison of measured and simulated temperatures revealed thermoregulation in children to be similar to that of adults. Based on this finding, we calculated the body-core temperature elevation in a 3-year-old child and an adult for plane-wave exposure at the basic restriction in the international guidelines. The body-core temperature elevation in the 3-year-old child phantom was 0.03 deg. C at a whole-body-averaged specific absorption rate of 0.08 W kg{sup -1}, which was 35% smaller than in the adult female. This difference is attributed to the child's higher body surface ...

2008-09-21

174

Experimental evaluation of angularly-variable fiber geometry for targeting depth-resolved reflectance from layered epithelial tissue phantoms  

Science.gov (United States)

The aim of the present study focuses on experimentally demonstrating the efficacy of using angularly-variable fiber geometry to achieve the desired tissue-layer selection and probing depths with the further objective of enhancing the sensitivity and specificity of spectral diagnosis in stratified architectures that resemble human cervical epithelia. The morphological and biochemical features of epithelial tissue vary in accordance with tissue depths; consequently, the accuracy of spectroscopic diagnosis of epithelial dysplasia may be enhanced by probing the optical properties of this tissue. When correlated to cellular dysplasia, layer-specific changes in tissue optical properties may be deciphered by reflectance spectroscopy coupled with angularly-variable fiber geometry. This study addresses the utility of using such angularly-variable fiber geometry for resolving spatially-specific spectral signatures of tissue pathology. This is accomplished by interpreting and analyzing the ...

2007-03-01

175

Construction of a homogeneous phantom for radiographic image standardization; Construcao de um fantoma homogeneo para padronizacao de imagens radiograficas  

Energy Technology Data Exchange (ETDEWEB)

The principle of radiodiagnosis consists in the fact the X-ray beam is attenuated at different degrees by distinct tissues. For this reason, the anatomical structures have distinct radiological opacities, that produce the radiographic image. The progresses in radiology are related to the development if new radiographic image formation systems that enable an amplification in the quality, with low dose and/or risk to the patient. The objective of this work is the sensitometric valuation of a screen-film combination, that is still the most used, for the standardization, of radiographic images. Thinking about this, were constructed homogeneous phantoms of the chest, skull and pelvis, for the calibration of X-ray beams, with the purpose of obtaining radiographic images of good quality, basing in the routine of a radiodiagnosis service and in the scientific knowledge. Questions were approached about the choice of the suitable equipment, that allow the obtention of k Vp ...

1996-12-31

176

Computed radiography. Evaluation of its role in the mass survey for lung cancer: Phantom study  

Energy Technology Data Exchange (ETDEWEB)

In an effort to evaluate the feasibility of introducing computed radiography (FCR) into mass screening for lung cancer, the ability of FCR to detect nodules one cm in diameter was examined using a humanoid chest phantom. Based on the receiver operating characteristic (ROC) analysis, the detectability of FCR was compared with that of conventional radiography and photofluorography. The values of area under ROC curves were higher for FCR (0.963 for image similar to that with conventional film-intensifying screen system, image A; and 0.952 for processed image, image B) than the other two methods (0.774 for radiography and 0.789 for photofluorography). Degradation of image quality in FCR could be avoided by a wide latitude even if proper exposure techniques might not be employed. Images A and B in FCR yielded excellent delineation for nodules in the lung field and in the retrocardiac and subdiaphragmatic regions, respectively. This may have implications for the value of ...

1987-12-01

177

Computed radiography for major airway in pediatrics  

International Nuclear Information System (INIS)

This paper shows the efficacy of computed radiography for major airway in pediatrics. For this purpose, we examined 40 children (range 2 weeks to 14 years; mean 2.3 years) using Fuji Computed Radiography (FCR) and radiation dose using pediatric phantom under FCR and conventional film and screen system. In comparison study with FCR and conventional film and screen system, FCR images are superior to conventional system in all cases. Scorings were done for the quality of the image of the pharynx, the trachea, and both main bronchi. In phantom study to check radiation dose, radiation dose could be reduced 1/6 of the value using high speed film and screen and 1/15 of the value using conventional speed film and screen. FCR also showed clear airway images in all cases but technical failure to evaluate the clinical lesion. These results suggest that FCR is the adequate imaging modality to evaluate the major airway in children. (author).

1986-01-01

178

Calculating electron dose using a convolution/superposition method. 120  

International Nuclear Information System (INIS)

The calculation of electronn beam dose using an algorithms similar to convolution/superposition methods for photon beams [1,2,3,4] is explored. The distribution of dose deposited by a number of monoenergetic, point-monodirectional electron pencil beams is first determined using the Monte Carlo method [5,6]. These elementary distributions are combined to model distributions that would result from the spectrum of incident energies and angles [6,7] present in a clinical beam. These modified distributions are then stored for use as kernels in the dose calculation. In the case of a homogeneous phantom, the relative fluence distribution is convolved with the stored kernels to obtain thhe dose distributions in 3 dimensions. Since the kernels cannot be assumed to be spatially invariant in a heterogeneous water-like phantom, the dose deposited on paths from the interaction site to all the dose deposition sites is approximated by scaling the kernels to ...

179

Body dose conversion factors for computerized tomography  

International Nuclear Information System (INIS)

While there have been many experimental and calculational investigations on absorbed dose distribution in the patient resulting from conventional X-ray procedures, such data for computerized tomography (CT) are still sparse. As this diagnostic procedure has shown a rapid increase in application during recent years, we have determined absorbed dose to body organs in a human phantom resulting from CT examinations. The exposure model consists of the heterogeneous MIRD-5 phantom and a suitable Monte-Carlo method to calculate absorbed dose to organs of interest. The exposure conditions are specified according to the exposure specifications of a CT-scanner currently in use. The calculations cover the range of body tissues of interest in terms of organ absorbed doses as well as a risk weighted absorbed dose. A detailed example showing the calculation of red bone marrow dose is given and a somatic effective dose equivalent Hsub(ES) is calculated for ...

1980-10-31

180

Analysis on Dose Distribution in Heterogeneous Condition for Narrow 6 MV X-ray Beams  

International Nuclear Information System (INIS)

Advanced modality of high-precision radiotherapy fulfilled by a composition of large numbers of small field beams called 'beamlets' can be achieved via nonuniform intensity fluencies. In case of radiation measurements and calculations with narrow high-energy photon beams, however, an accurate two-dimensional dosimetry is a challenging task due to dosimetrically unfavorable phenomena such as dramatic changes of the dose at the field boundaries, dis-equilibrium of the electrons resulting from larger detector volume, and non-uniformity between the detector and the phantom materials. Meanwhile, with the advantages of high spatial resolution and wide range of absorbed doses, there is a growing demand of GAFCHROMICat..EBT film to confirm delivered dose distribution. Especially, the effects from the material differences between the phantom and the film can be minimized in the heterogeneous condition since the GAFCHROMICat..EBT film is composed of ...

2010-10-01

181

An adaptive filter to approximate the Bayesian strategy for sonographic beamforming.  

Science.gov (United States)

A first-principles task-based approach to the design of medical ultrasonic imaging systems for breast lesion discrimination is described. This study explores a new approximation to the ideal Bayesian observer strategy that allows for object heterogeneity. The new method, called iterative Wiener filtering, is implemented using echo data simulations and a phantom study. We studied five lesion features closely associated with visual discrimination for clinical diagnosis. A series of human observer measurements for the same image data allowed us to quantitatively compare alternative beamforming strategies through measurements of visual discrimination efficiency. Employing the Smith-Wagner model observer, we were able to breakdown efficiency estimates and identify the processing stage at which performance losses occur. The methods were implemented using a commercial scanner and a cyst phantom to explore development of spatial filters for systems ...

2010-07-19

182

A convolution/superposition method using primary and scatter dose kernels formed for energy bins of X-ray spectra reconstructed as a function of off-axis distance: a theoretical study on 10-MV X-ray dose calculations in thorax-like phantoms  

British Library Electronic Table of Contents (United Kingdom)

A convolution/superposition method is proposed for use with primary and scatter dose kernels formed for energy bins of X-ray spectra reconstructed as a function of off-axis distance. It should be noted that the number of energy bins is usually about ten, and that the reconstructed X-ray spectra can reasonably be applied to media with a wide range of effective Z numbers, ranging from water to lead. The study was carried out for 10-MV X-ray doses in water and thorax-like phantoms with the use of open-jaw-collimated fields. The dose calculations were made separately for primary, scatter, and electron contamination dose components, for which we used two extended radiation sources: one was on the X-ray target and the other on the flattening filter. To calculate the in-air beam intensities at po...

2011-01-01

183

Radiation exposure of patients and operators during interventional radiology  

International Nuclear Information System (INIS)

Surface doses received by patients and operators were measured during 30 interventional radiological procedures (ten percutaneous transhepatic biliary drainages, ten percutaneous nephrostomies, ten percutaneous transluminal angioplasties). In addition, organ doses to the patient were determined using an Alderson-Rando phantom. These served as a basis for calculating the so-called somatic dose indices. It was found that the somatic radiation risk to the patient is relatively small despite prolonged periods of fluoroscopy. However, exposure of the hands and lenses of the operator could easily reach the limits thought acceptable while carrying out these procedures with additional angiography. (orig).

1986-01-01

184

Organ doses to atomic bomb survivors during photofluorography, fluoroscopy and computer tomography  

Energy Technology Data Exchange (ETDEWEB)

Doses to the salivary glands, thyroid gland, breast, lung, stomach and colon during mass radiological gastric screening, mass radiographic chest screening, upper gastrointestinal series and computed tomography were determined by exposing a female human phantom to simulated radiological X-ray examinations as performed in community hospitals. The doses were measured using thermoluminescent dosemeters, and the results will be used to document organ doses received by participants in the Atomic Bomb Casualty Commission/Radiation Effects Research Foundation Adult Health Study. (Author).

1991-08-01

185

Organ doses to atomic bomb survivors during photofluorography, fluoroscopy and computer tomography  

International Nuclear Information System (INIS)

Doses to the salivary glands, thyroid gland, breast, lung, stomach and colon during mass radiological gastric screening, mass radiographic chest screening, upper gastrointestinal series and computed tomography were determined by exposing a female human phantom to simulated radiological X-ray examinations as performed in community hospitals. The doses were measured using thermoluminescent dosemeters, and the results will be used to document organ doses received by participants in the Atomic Bomb Casualty Commission/Radiation Effects Research Foundation Adult Health Study. (Author).

1991-01-01

186

Organ doses and integral doses in X-ray diagnosis of the chest and of the head  

International Nuclear Information System (INIS)

Organ and tissue doses and integral doses in patients due to diagnostic x-ray examinations of the chest and of the head will be presented. These data have been obtained by measuring the dose distributions in man phantoms by LiF-dosimetry. The data will be compared with data obtained by Monte-Carlo calculations. To obtain average organ doses for a special type of examination for the population or for a specified subpopulation in the variation of the exposure, data due to the different techniques used by the different radiologists has to be known. Such data will be presented. The results of the investigation will be discussed in connection with the concept of the 'somatic significant.

1977-04-01

187

Mathematical child phantom for the calculation of dose to the organs at risk  

Energy Technology Data Exchange (ETDEWEB)

In order to calculate the doses received by the organs of 530 children treated by radiation for cancer between 1945 and 1969 at the G. Roussy Institute, we have developed a computer program for organ location calculation. To calculate the location of each child's organs of interest at the time of the treatment, only two parameters are necessary; sex and height or sex and age when the height at the time of the treatment is unknown. The algorithm is based on the metric studies of growth known as auxology. Each organ is located by one point representing its center. The model has been checked on 100 healthy children.

1988-05-01

188

Electron beam therapy in carcinoma of the buccal mucosa  

Energy Technology Data Exchange (ETDEWEB)

Electron beam therapy has often been used for radiation therapy of carcinomas of the buccal mucosa, though side effects, including stomatitis and dermatitis, are known to exist. We experimented using the additional back scatter and transit with the phantom under a lead plate within the irradiation field, in order to better focus the dose on the target volume moreover, we fabricated a mouthpiece fitted with a lead plate shaped to the target volume, and with respect to the influence of the mouthpiece on stomatitis and dermatitis, obtained good clinical results. (author).

1990-10-01

189

Electron beam therapy in carcinoma of the buccal mucosa  

International Nuclear Information System (INIS)

Electron beam therapy has often been used for radiation therapy of carcinomas of the buccal mucosa, though side effects, including stomatitis and dermatitis, are known to exist. We experimented using the additional back scatter and transit with the phantom under a lead plate within the irradiation field, in order to better focus the dose on the target volume moreover, we fabricated a mouthpiece fitted with a lead plate shaped to the target volume, and with respect to the influence of the mouthpiece on stomatitis and dermatitis, obtained good clinical results. (author).

190

Dual-field rotational (DFR) technique for total-skin electron-beam therapy (TSEBT)  

Energy Technology Data Exchange (ETDEWEB)

Comparison of dosimetry measured in a noncylindrical Rando-Alderson phantom by two-field, four-field, and six-field total-skin electron-beam therapy (TSEBT) techniques with our dual-field rotational (DFR) technique reveals a superior dosimetry for the latter. Our technique of dual-field rotational DFR-TSEBT is described in detail, and its advantages and indications for the primary management of cutaneous T-cell lymphoma (CTCL) and Kaposi's sarcoma (KS) are discussed.

1987-08-01

191

Clinical implementation of a convolution based algorithm for 3D treatment planning  

International Nuclear Information System (INIS)

Purpose/Objective: With the advent of computed tomography and magnetic resonance imaging, the three dimensional representation of the patient anatomy has become an invaluable resource for better diagnosis and delineation of the target volume and sensitive structures in radiation therapy. Although the therapeutic linear accelerator industry has made available highly sophisticated equipment, the aggressiveness in dose prescription and delivery has to be complimented by accurate dose computation methods. We have adopted a convolution/superposition algorithm for the calculation of absolute dose that fully accounts for the external shape and internal structure of the patient for photon treatment radiotherapy. In this paper, we will discuss the principles of the convolution algorithm and we will show how the computed dose compares to clinically relevant treatment techniques. Materials and Methods: A computer controlled data acquisition system and a water tank where used to measure depth ...

192

A new type active personal dosemeter with a solid state detector  

International Nuclear Information System (INIS)

We have developed a new type personal dosemeter by using a B-10 doped silicon p-n junction detector with a polyethylene radiator and a polyethylene moderator. The purpose of this study was to develop a real time neutron dosemeter with a nearly flat response in the energy range from thermal to 15 MeV and low angular dependence to the incident neutron direction. The neutron response of the dosemeter was obtained with the Monte Carlo calculation and the monoenergetic neutron experiment in a free air field and also under a condition attached on a phantom.

1988-04-01

193

Experimental studies of compact real-time neutron dosimeters  

International Nuclear Information System (INIS)

Full text: Semiconductor detectors coated with boron or lithium compounds have been studied for neutron detection for decades but, until recently, have been limited to thermal neutron detection efficiencies of less than 5%. We reported previously on development and simulation studies of perforated detectors whose perforations are filled with neutron-reactive material in order to produce higher detection efficiencies. Incorporation of bare and cadmium-backed detectors into battery-powered devices with low-power electronics enables us to produce compact personal neutron dosimeters that provide LED readout of counts, which can be related approximately to neutron dose. We report here on experimental studies with such compact devices; devices capable of direct readout in dose units are anticipated. The thermal and epithermal neutron flux densities from the tangential beam tube of the TRIGA Mark II reactor at Kansas State University were measured. Then, thermoluminescent dosimeters (some ...

2008-06-01

194

Usefulness of "1"8F-FDG PET in intrahepatic cholangiocarcinoma  

International Nuclear Information System (INIS)

Surgical resection is the only curative treatment strategy for intrahepatic cholangiocarcinoma (CC). Therefore, accurate staging is essential for appropriate management of patients with CC. We assessed the usefulness of 2-["1"8F]fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) in the staging of CC. We undertook a retrospective review of FDG PET images in 21 patients (10 female, 11 male; mean age 57 years) diagnosed with CC. Ten patients had hilar CC and 11, peripheral CC. Patients underwent abdominal magnetic resonance imaging (MRI) (n=20) and computed tomography (CT) (n=12) for the evaluation of primary tumours, and chest radiography and whole-body bone scintigraphy for work-up of distant metastases. For semi-quantitative analysis, the maximum voxel standardised uptake value (SUV_m_a_x) was obtained from the primary tumour. All peripheral CCs showed intensely increased FDG uptake, and some demonstrated ring-shaped uptake corresponding to ...

2003-11-01

195

The use of short-echo-time {sup 1}H MRS for childhood cerebellar tumours prior to histopathological diagnosis  

Energy Technology Data Exchange (ETDEWEB)

Proton magnetic resonance spectroscopy (MRS) measures concentrations of metabolites in vivo and provides a powerful method for identifying tumours. MRS has not entered routine clinical use partly due to the difficulty of analysing the spectra. To create a straightforward method for interpreting short-echo-time MRS of childhood cerebellar tumours. Single-voxel MRS (1.5-T Siemens Symphony NUM4, TR/TE 1,500/30 ms) was performed at presentation in 30 children with cerebellar tumours. The MRS results were analysed for comparison with histological diagnosis. Peak heights for N-acetyl aspartate (NAA), creatine (Cr), choline (Cho) and myo-inositol (mIns) were determined and receiver operator characteristic curves used to select ratios that best discriminated between the tumour types. The method was implemented by a group of clinicians and scientists, blinded to the results. A total of 27 MRS studies met the quality control criteria. NAA/Cr >4.0 distinguished all but ...

2007-11-15

196

Menstrual variation of breast volume and T{sub 2} relaxation times in cyclical mastalgia  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Hormonal activity causes breast volume to change during the menstrual cycle. One possible cause of this volume change is thought to be due to water retention or oedema within the tissues. We used magnetic resonance imaging (MRI) to study the variation in breast volume and {sup 1}H Magnetic Resonance Spectroscopy (MRS) to measure T{sub 2} relaxation times which are known to increase with increasing tissue water content. We hypothesised that an increase in breast volume will elevate T{sub 2} relaxation due to the presence of an increased water content within the breast. T{sub 2} Relaxation time and volume were studied in fifteen control subjects and in a cohort of eight patients with cyclical mastalgia in order to determine whether changes in breast volume and T{sub 2} relaxation times differed in controls and patients during menses, ovulation and premenses. Method: Breast volume was determined by the Cavalieri method in combination with point counting techniques on MR images ...

2008-02-15

197

Hypercapnic normalization of BOLD fMRI: comparison across field strengths and pulse sequences.  

DEFF Research Database (Denmark)

The blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) signal response to neural stimulation is influenced by many factors that are unrelated to the stimulus. These factors are physiological, such as the resting venous cerebral blood volume (CBV(v)) and vessel size, as well as experimental, such as pulse sequence and static magnetic field strength (B(0)). Thus, it is difficult to compare task-induced fMRI signals across subjects, field strengths, and pulse sequences. This problem can be overcome by normalizing the neural activity-induced BOLD fMRI response by a global hypercapnia-induced BOLD signal. To demonstrate the effectiveness of the BOLD normalization approach, gradient-echo BOLD fMRI at 1.5, 4, and 7 T and spin-echo BOLD fMRI at 4 T were performed in human subjects. For neural stimulation, subjects performed sequential finger movements at 2 Hz, while for global stimulation, subjects breathed a 5% CO(2) gas mixture. Under all conditions, ...

2004-01-01

198

Experimental verification of convolution/superposition photon dose calculations for radiotherapy treatment planning  

International Nuclear Information System (INIS)

This work describes an experimental verification of the two-photon dose calculation engines available on the Helax-TMS (version 6.1) commercial radiotherapy treatment planning system. The performance of the pencil beam convolution and the collapsed cone superposition algorithms was examined for 4, 6, 15 MV beams, under a range of clinically relevant irradiation geometries. Comparisons against measurements were carried out in terms of absolute dose, thus assessment of the accuracy of monitor unit (MU) calculations was also carried out. Results show that both algorithms agree with measurement to acceptable tolerance levels in most cases in homogeneous water-equivalent media irradiated under full scatter conditions. The collapsed cone algorithm slightly overestimates the penumbra width and this is mainly due to discretization effects of the fluence matrix. The accuracy of this algorithm strongly depends on the resolution of the patient density matrix. It is recommended that the density ...

2003-09-07

199

Collapsed cone convolution and analytical anisotropic algorithm dose calculations compared to VMC++ Monte Carlo simulations in clinical cases  

International Nuclear Information System (INIS)

The purpose of this work was to study and quantify the differences in dose distributions computed with some of the newest dose calculation algorithms available in commercial planning systems. The study was done for clinical cases originally calculated with pencil beam convolution (PBC) where large density inhomogeneities were present. Three other dose algorithms were used: a pencil beam like algorithm, the anisotropic analytic algorithm (AAA), a convolution superposition algorithm, collapsed cone convolution (CCC), and a Monte Carlo program, voxel Monte Carlo (VMC++). The dose calculation algorithms were compared under static field irradiations at 6 MV and 15 MV using multileaf collimators and hard wedges where necessary. Five clinical cases were studied: three lung and two breast cases. We found that, in terms of accuracy, the CCC algorithm performed better overall than AAA compared to VMC++, but AAA remains an attractive option for routine use in the clinic due ...

2007-07-07

200

Collapsed cone and analytical anisotropic algorithm dose calculations compared to VMC++ Monte Carlo simulations in clinical cases  

International Nuclear Information System (INIS)

The purpose of this work was to study and quantify the differences in dose distributions computed with some of the newest dose calculation algorithms available in commercial planning systems. The study was done for clinical cases where large density inhomogeneities were present. Three dose algorithms were used: a pencil beam like algorithm, the anisotropic analytic algorithm (AAA), a convolution superposition algorithm, collapsed cone convolution (CCC) and a Monte Carlo program, voxel Monte Carlo (VMC++). The dose calculation algorithms were compared under static field irradiations at 6 MV and 15 MV using multileaf collimators and hard wedges where necessary. Five clinical cases were studied: three lung and two breast cases. We found that the CCC algorithm performed overall better than AAA compared to VMC++, but AAA remains an attractive option for routine use in the clinic due to its short computation times. Dose differences between the different algorithms for ...

2007-06-01

201

Brain SPECT of chronic fatigue syndrome (CFS): SPM analysis of two age groups  

International Nuclear Information System (INIS)

Full text: Chronic fatigue syndrome (CFS) is a complex disorder characterised by profound fatigue and neuropsychiatric dysfunction. Previous studies with cerebral perfusion SPECT (rCBF) scans were performed with inhomogeneous patient populations and were not analysed with Statistical Parametric Mapping (SPM). We have used SPM to study subjects with moderate CFS based on the Fukuda criteria, who were not on medication and not depressed, compared to age matched control subjects. An apparent bimodal age distribution has been observed in CFS. Subjects were therefore divided into two age groups: 16-35 or under 35 (17 CFS, 11 control) and 36-61 or over 35 (15 CFS, 15 control). HMPAO brain SPECT was acquired on a 3-head camera. After lower window scatter subtraction, reconstruction with attenuation correction (mu=0.15/cm) and editing of facial activity, scans were spatially normalised (affine + 2x3x2 nonlinear) to SPM's anatomical space. SPM statistical analysis yielded the location, ...

2002-05-04

202

Comparison of dose calculation algorithms in phantoms with lung equivalent heterogeneities under conditions of lateral electronic disequilibrium  

International Nuclear Information System (INIS)

An extensive set of benchmark measurement of PDDs and beam profiles was performed in a heterogeneous layer phantom, including a lung equivalent heterogeneity, by means of several detectors and compared against the predicted dose values by different calculation algorithms in two treatment planning systems. PDDs were measured with TLDs, plane parallel and cylindrical ionization chambers and beam profiles with films. Additionally, Monte Carlo simulations by meansof the PENELOPE code were performed. Four different field sizes (10x10, 5x5, 2x2, and1x1 cm"2) and two lung equivalent materials (CIRS, #rho#_e"w=0.195 and St. Bartholomew Hospital, London, #rho#_e"w=0.244-0.322) were studied. The performance of four correction-based algorithms and one based on convolution-superposition was analyzed. The correction-based algorithms were the Batho, the Modified Batho, and the Equivalent TAR implemented in the Cadplan (Varian) treatment planning system and the TMS Pencil Beam ...

2004-10-01

203

Application of low-dose radiation protocols in survey CT scans  

International Nuclear Information System (INIS)

Objective: To characterize the protocols with low-dose radiation in survey CT scans for localization. Methods: Eighty standard adult patients, head and body phantoms were recruited. Default protocols provided by operator's manual setting were that all the tube voltage for head, chest, abdomen and lumbar was 120 kV; the tube currents were 20,10,20 and 40 mA, respectively. Values of kV and mA in the low-dose experiments were optimized according to the device options. For chest and abdomen, the tube position were compared between default (0 degree) and 180 degree. Phantoms were scanned with above protocols, and the radiation doses were measured respectively. Paired t-test were used for comparisons of standard deviation in CT value, noise and exposure surface dose (ESD) between group with default protocols and group with optimized protocols. Results: The optimized protocols in low-dose CT survey scans were 80 kV, 10 mA for head, 80 kV, 10 mA for ...

2009-08-01

204

Accuracy of two heterogeneity dose calculation algorithms for IMRT in treatment plans designed using an anthropomorphic thorax phantom  

International Nuclear Information System (INIS)

With the advent of intensity-modulated radiation therapy (IMRT), the inclusion of heterogeneity corrections is further complicated by the conformal delivery of many small beams forming steep dose gradients. Radiation treatment planning has evolved to take into account even small changes in tissue density so that the dose to tumor can be further optimized. However, different treatment planning systems incorporate different heterogeneity correction algorithms, and it is unclear whether any of these algorithms are superior to others in terms of accurately predicting delivered radiation doses relative to measurement in a clinical setting. The purpose of this study was to determine the accuracy of heterogeneity dose calculations from two widely used IMRT treatment planning systems (Pinnacle and Corvus) against measurement. These two systems handle heterogeneity dose corrections by means of a collapsed-cone convolution superposition algorithm and a finite-size pencil-beam algorithm with ...

2007-05-01

205

The Prevention of Periodontal Bone Loss at the Osteotomy Site After Anterior Segmental and Dento-Osseous Osteotomy  

British Library Electronic Table of Contents (United Kingdom)

Purpose Degeneration of the gingival margin and periodontal bone loss between segments can occur in various segmental osteotomies. However, treatment and management of these problems have not yet been resolved; improvement of the conventional method is necessary. The purpose of this retrospective study is to evaluate the usefulness and advantage of orthodontic devices in osteotomies. Patients and Methods Forty Japanese adults presented with jaw deformities diagnosed as mandibular prognathism with maxillary protrusion, bimaxillary protrusion, and anterior crowding. Of these 40 patients, 20 (group 1) underwent anterior segmental osteotomy or dento-osseous osteotomy along with our original orthodontic periodontal management. The remaining 20 (group 2) patients underwent conventional procedure...

2006-01-01

206

The Harboore project  

Energy Technology Data Exchange (ETDEWEB)

Babcock and Wilcox Volund is a major European provider of energy producing plants based on biomass and waste materials, which was founded in 1898 and today employs about 400 persons with headquarters and manufacturing in Esbjerg, Denmark. The R and D staff is about 10 persons, concentrating on gasification and improvement of traditional products. The Company turnover is about 120 mio. Euro annually, of which about 80 % is exported (50 % outside Europe - mostly far East). In 2000 the Company was acquired by US Company Babcock and Wilcox. In 1988 Volund initiated the development of updraft wood-chips gasifier Technology, which led to the commissioning of the Harboore gasifier early 1994. The work was supported in part by the Danish ELKRAFT Power Utilities and the Danish Energy Agency. The development process was carried out until 2002 and Volund now just concluded a license agreement with the Japanese engineering Company JFE. The overall layout for the Harboore plant ...

2003-07-01

207

Sulzer RTA dual-fuel engine - natural gas instead of diesel oil  

Energy Technology Data Exchange (ETDEWEB)

Testbed trials of the Sulzer RTA84 dual-fuel engine were successfully completed at the IHI Aioi engine works (Japan) in April 1986. This newly-developed engine, output range 15 to 40 MW, can be operated with both diesel or heavy oil and methane gas at comparable thermal efficiency and unchanged output. The RTA dual-fuel engine was developed in close collaboration between Sulzer Brothers Limited, Switzerland and its Japanese licensees Ishikawajima-Harima Heavy Industries Co. Ltd. (IHI), Nippon Kokan KK (NKK) and Sumitomo Heavy Industries Ltd. (SHI). Intended for the propulsion of LNG carriers, where the boil-off gas from the ship's cargo is exploited or for the generation of electricity in stationary plants, the RTA dual-fuel engine is an economic and reliable alternative to the steam or gas turbines.

1987-06-01

208

Relationship between the lability of sediment-bound metals (Cd, Cu, Zn) and their bioaccumulation in benthic invertebrates  

British Library Electronic Table of Contents (United Kingdom)

The present study has investigated metal contamination at nine sites (10 sampling stations) from the English Channel to the Mediterranean Sea, including low level and highly contaminated sediments. Both total and labile concentrations of metals were determined in superficial sediments. The influence of different pHs was tested and metal lability at pHs encountered in the gut of invertebrates (the ragworm Nereis diversicolor, the blue mussel Mytilus edulis, the Japanese oyster Crassostrea gigas) was compared with the distribution of metals in various operationally defined geochemical fractions. Cd showed the highest lability and Cu the lowest, whereas Zn lability was intermediate. Metal concentrations were determined in bivalves at six sites and in worms at three sites. Cd in living organis...

2007-01-01

209

RTA dual-fuel engine - natural gas instead of diesel oil  

Energy Technology Data Exchange (ETDEWEB)

Test bed trials of the Sulzer RTA84 dual-fuel engine were successfully completed at the IHI Aioi engine works (Japan) in April 1986. This newly-developed engine-type, output range 15 to 40 MW, can be operated with both diesel or heavy oil and methane gas at comparable thermal efficiency and unchanged output. The RTA dual-fuel engine was developed in close collaboration between Sulzer Brothers Limited and its Japanese licenses. Intended for the propulsion of LNG carriers, where the boil-off gas from the ship's cargo is exploited for the generation of electricity in stationary plants, the RTA dual-fuel engines is an economic and reliable alternative to the steam or gas turbine. The performance of the engine is discussed.

1987-01-01

210

Pirfenidone in idiopathic pulmonary fibrosis: the CAPACITY program  

British Library Electronic Table of Contents (United Kingdom)

Idiopathic pulmonary fibrosis is the most lethal form of diffuse lung fibrosis, killing approximately half of those affected within 2-3 years of diagnosis. Until recently, no therapies had been shown to have an impact on disease progression. The Clinical Studies Assessing Pirfenidone (Esbriet) in IPF: Research of Efficacy and Safety Outcomes (CAPACITY) program comprised two almost identical double-blind placebo-controlled studies assessing the effects of pirfenidone on change in forced vital capacity, the primary end point, over a 72-week period. One of these studies was positive, matching in magnitude the benefit seen in two previous positive Japanese studies. The other study did not meet its primary end point but positive trends were consistent in this and a number of secondary end point...

2011-01-01

211

Overview on seismic evaluation and retrofitting within JICA Technical Cooperation Project on reduction of seismic risk in Romania  

International Nuclear Information System (INIS)

The objective of this paper is to give an overview on the seismic evaluation and retrofitting procedures of reinforced concrete buildings within JICA technical cooperation project in Romania. The content of the paper covers a) an outline of the seismic evaluation; history and comparison of Romanian seismic design codes with the Japanese seismic evaluation guidelines, b) an outline of the retrofitting techniques which were transferred from Japan to Romania and structural tests for retrofitting techniques employed in Romania and c) retrofitting details that were used by JICA/NCSRR in the retrofitting design of two vulnerable buildings in Bucharest. The above-mentioned retrofitting projects are now under development of detailed design and therefore, in the near future, refining and improvement of solutions will be performed. (authors)

2007-04-26

212

On the long term indoor radon concentration measurements the basement of Japanese hospitals  

International Nuclear Information System (INIS)

Long term indoor radon gas measurements using a passive monitor were conducted in the basement rooms of five hospitals, which are built in the Tokyo metropolitan area. The ventilation rate averaged over all hospital was 12.3 air change per hour (ACH). The highest radon concentration was 56.3 Bq/m"3. The value averaged concentration over all hospital and all season was 20 Bq/m"3. But the average of the two hospitals were twice as high as those of three others. Since the total ventilation rate integrated over a day is not different much, the reason of the concentration difference is considered to be the difference in radon emission rate from concrete wall and soil of the each hospital. Though we inquired workers about 'Environmental complaints', it do not show the direct relation between radon and environmental complaints. (author)

213

Liberalization, internationalization, and globalization: charting the course of foreign investment in the finance and commerce of Japan, 1945-2009  

British Library Electronic Table of Contents (United Kingdom)

As the world's largest creditor nation, with some of the world's largest banks and leading industries, Japan is often portrayed as an economic and financial superpower. With long-established 'Western-style' financial institutions to represent it in all the world's major financial capitals and markets, a technologically savvy Japan is often said to be positioning itself to lead Asia, the Asia/Pacific region, or even the entire world, into the marvels of the twenty-first century. Against this continuing rhetorical backdrop, however, fundamental questions arise as to Japan's ability to internationalize in today's increasingly globalized world economy. Domestically, only a very limited presence is permitted to the foreigner in the Japanese economy, especially in the commanding heights of finan...

2010-01-01

214

Language and Music in the Musician Brain  

British Library Electronic Table of Contents (United Kingdom)

Abstract Results of numerous experiments conducted over the past 15-years by using behavioural as well as brain imaging methods have shown that musical expertise influences brain anatomy, brain functions and behaviour. The musician- brain is thus considered as a very good model of brain plasticity. Moreover, many results have demonstrated that musical expertise not only impacts on music processing but also on several aspects of speech processing including lexical pitch, sentence intonation and the metric structure of words. Conversely, recent results indicated that linguistic expertise with tone or quantity languages such as Mandarin Chinese, Thai, Finnish and Japanese, influences the processing of harmonic tones and musical intervals. We discuss possible interpretations of these findings ...

2011-01-01

215

Japanese will join West Germany in funding coal-liquefaction project  

Science.gov (United States)

The funding for a coal-liquefaction demonstration plant near Morgantown, W.Va., appears more certain since Japan has committed $175 million toward the project. West Germany has already signed a memorandum of understanding to contribute 25% of the expected $700 million cost. West Virginia Governor J. Rockefeller has said that he feels sure the Carter Administration will approve the project since half the money is assured. The solvent-refined-coal (SRC) demonstration program began in July 1978 with the award of two separate multiphased contracts for development of a solid process, SRC-I, and a liquid process, SRC-II. The US Department of Energy is expected to choose one of the projects for detailed design and construction by the end of fiscal 1979.

1979-05-16

216

Japan Renal Biopsy Registry: the first nationwide, web-based, and prospective registry system of renal biopsies in Japan  

British Library Electronic Table of Contents (United Kingdom)

Background The Committee for the Standardization of Renal Pathological Diagnosis and the Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started the first nationwide, web-based, and prospective registry system, the Japan Renal Biopsy Registry (J-RBR), to record the pathological, clinical, and laboratory data of renal biopsies in 2007. Methods The patient data including age, gender, laboratory data, and clinical and pathological diagnoses were recorded on the web page of the J-RBR, which utilizes the system of the Internet Data and Information Center for Medical Research in the University Hospital Medical Information Network. We analyzed the clinical and pathological diagnoses registered on the J-RBR in 2007 and 2008. Results Data were collected from 818 patien...

2011-01-01

217

Honokiol enhances adipocyte differentiation by potentiating insulin signaling in 3T3-L1 preadipocytes  

British Library Electronic Table of Contents (United Kingdom)

Adipose tissue plays an essential role in energy homeostasis as a metabolic and endocrine organ. Accordingly, adipocytes are emerging as a major drug target for obesity and obesity-mediated metabolic syndrome. Dysfunction of enlarged adipocytes in obesity is involved in obesity-mediated metabolic syndrome. Adipocytokines, such as adiponectin released from small adipocytes, are able to prevent these disorders. In this study, we found that honokiol, an ingredient of Magnolia officinalis used in traditional Chinese and Japanese medicines, enhanced adipocyte differentiation in 3T3-L1 preadipocytes. Oil Red O staining showed that treatment with honokiol in the presence of insulin dose-dependently increased lipid accumulation in 3T3-L1 preadipoyctes although its activity was weak compared with r...

2011-01-01

218

Heightened awareness of a researcher's own culture through carrying out research on development cooperation  

British Library Electronic Table of Contents (United Kingdom)

In this paper I argue that when a researcher is a research instrument, it is likely that the researcher would develop a heightened awareness of his/her own cultural conditioning, especially in the case of cross-cultural studies. And that such awareness would make him/her realise that one's own cultural background may indeed have an influence on formulating his/her research methodology. The paper is based on my own research project on development cooperation between Japan and Cambodia, whereby I examined the perceptions of Cambodians and Japanese on what an appropriate power relationship between donors and recipients should be. At the outset of my research project, I paid little attention to my own cultural condition and the role it might play in my study, though I was aware that being Japa...

2011-01-01

219

Habitat segregation and genetic relationship of two heptageniid mayflies, Epeorus latifolium and Epeorus l-nigrus, in the Shinano-gawa River basin  

British Library Electronic Table of Contents (United Kingdom)

The heptageniid mayflies Epeorus latifolium and Epeorus l-nigrus are often the dominant species in the upper and midstream areas of Japanese rivers; as such, they play a significant role in river ecosystems. However, although these two species have been identified using the morphological characteristics of the male in its adult stage, it is impossible to differentiate them in their nymphal stage. We conducted a study to elucidate their distribution pattern, i.e., the current distribution of these two species in the Shinano-gawa River basin, based on quantitative field sampling and genetic analysis of nymphs and also some male adults; for these, it was possible to differentiate between the two species reliably. The data collected from the 30 study sites of the 1-year-long study revealed tha...

2011-01-01

220

GPS impact on geodesy  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this paper is to check up a GPS (global positioning system) impact on scientific research activities of the Geodetic Society of Japan. First, it is mentioned that the conventional geoid-based concept of 'gravity anomaly' should be changed to a new definition, according to the GPS-determined ellipsoidal height system. Secondly, the results of many experiments, which have been made to monitor ocean-plate motions relative to the Japanese island-arcs, demonstrate that GPS is a powerful tool for obtaining temporal changes in horizontal displacement induced by the plate motion. Therefore, it is suggested that terrestrial measurements, such as triangulation and long-range leveling, would be replaced by GPS measurements in near future. Moreover, it is pointed out that GPS geodesy should play an important role in monitoring secular sea level trend due to global warming of the atmosphere and ocean. 19 refs., 4 figs.

1992-12-25

221

Development of L-band pillbox RF window  

Energy Technology Data Exchange (ETDEWEB)

A pillbox RF output window was developed for the L-band pulsed klystron for the Japanese Hadron Project (JHP) 1-GeV proton linac. The window was designed to withstand a peak RF power of 6 MW, where the pulse width is 600 {mu}sec and the repetition rate is 50 Hz. A high power model was fabricated using an alumina ceramic which has a low loss tangent of 2.5x10{sup -5}. A high power test was successfully performed up to a 113 kW RF average power with a 4 MW peak power, a 565 {mu}sec pulse width and a 50 Hz repetition rate. By extrapolating the data of this high power test, the temperature rise of the ceramic is estimated low enough at the full RF power of 6 MW. Thus this RF window is expected to satisfy the specifications of the L-band Klystron. (author).

1994-12-31

222

Corrosion experiments and materials developed for the Japanese HLM systems  

British Library Electronic Table of Contents (United Kingdom)

The static corrosion tests in lead-bismuth eutectic (LBE) were conducted from 450degreeC to 600degreeC to understand corrosion behavior and develop corrosion resistant materials for heavy liquid metal systems. While increase of Cr content in steels enhances corrosion resistance in LBE, the effect approaches a constant value above 12wt% of Cr. Corrosion depth in LBE increases with increasing temperature and corrosion attack becomes severe above 550degreeC even under the condition of high oxygen concentration. Nickel dissolution and Pb-Bi penetration occur in 316SS and JPCA above 550degreeC under the condition of high oxygen concentration. When oxygen concentration decreases below the level of Fe oxide formation, corrosion attack on these steels also becomes violent due to dissolution of var...

2011-01-01

223

Cleansing of soils and underground waters in Japan; La depollution des sols et des eaux souterraines au Japon  

Energy Technology Data Exchange (ETDEWEB)

Japanese companies have developed suitable cleansing technologies and export their know-how. Some original technologies are developed today, like: in-situ chemical oxidation, iron confinement, hot-soil process, low-temperature catalytic decomposition or dechlorination of dioxins. However, some pollutions are still poorly considered (nitrates) or badly mastered (dioxins). This situation is partly due to late legal decisions and to limited pollution abatement measures. Japan is also very active in bio-cleansing research, and this, despite the lack of dialogue and directives at the national level. Several research programs with important funds have started since 1995. However, Japan is still at the preliminary stage in open-field applications of cleansing methods. (J.S.)

1999-11-01

224

Agent Simulation of Chain Bankruptcy  

CERN Document Server

We have conducted an agent-based simulation of chain bankruptcy. The propagation of credit risk on a network, i.e., chain bankruptcy, is the key to nderstanding largesized bankruptcies. In our model, decrease of revenue by the loss of accounts payable is modeled by an interaction term, and bankruptcy is defined as a capital deficit. Model parameters were estimated using financial data for 1,077 listed Japanese firms. Simulations of chain bankruptcy on the real transaction network consisting of those 1,077 firms were made with the estimated model parameters. Given an initial bankrupt firm, a list of chain bankrupt firms was obtained. This model can be used to detect high-risk links in a transaction network, for the management of chain bankruptcy.

2007-01-01

225

A comparison of convenience features for Japanese and American residential heat pumps  

Energy Technology Data Exchange (ETDEWEB)

The fundamental differences in the type of products sold in both Japan and the US, and some of the reasons for these differences, are outlined. Japan is the largest single country market for residential heat pumps, while the US represents the largest single country market for residential heating equipment. Quite different types and associated features of heat pumps are demanded in the USA and Japan. The term `convenience features`, used to describe the physical characteristics of the user interface device, is explained, as well as the fundamental reasons leading to the particular styles of product sold in each country: (1) product strategy and sales channels, (2) design of housing, (3) climatic factors, and (4) energy costs and distribution. It is stressed that there is no big cooling load in Japan. It is rather the comfort issue that drives the market for heat pumps

1996-07-01

226

1982 International Geoscience and Remote Sensing Symposium, Munich, West Germany, June 1-4, 1982, Digest. Volumes 1 and 2  

Energy Technology Data Exchange (ETDEWEB)

Theoretical and experimental data which have defined and/or extended the effectiveness of remote sensing operations are explored, with consideration given to both scientific and commercial activities. The remote sensing of soil moisture, the sea surface, and oil slicks is discussed, as are programs using satellites for studying geodynamics and geodesy, currents and waves, and coastal zones. NASA, Canadian, and Japanese radar and microwave passive and active systems are described, together with algorithms and techniques for image processing and classification. The SAR-580 project is outlined, and attention is devoted to satellite applications in investigations of the structure of the atmosphere, agriculture and land use, and geology. Design and performance features of various optical scanner, radar, and multispectral data processing systems and procedures are detailed.

1982-01-01

227

Visualization of disturbed flow with spin-echo and cine MR imaging  

International Nuclear Information System (INIS)

MR images of steady and pulsatile disturbed flow, obtained with use of flow-compensated spin-echo (SE) and cine pulse sequences, revealed excellent flow visualization in three dimensions. Phantoms, built from molds of actual blood vessels, reproduced laminar, disturbed, or turbulent flow. Video recording (VR), performed under conditions equivalent to those of the MR experiments, showed separation zones identical to those seen on SE images. Pulsatile flow studies showed complex patterns of vortical flow on cine images and VR. Varying pulse sequence details changed contrast but not flow patterns. The validation of MR observations by VR has implications for clinical cine imaging and low abnormal signals observed on MR angiograms.

228

Tracheal cross-sectional area in children: CT determination  

Energy Technology Data Exchange (ETDEWEB)

A computer method that calculates tracheal cross-sectional area by compensating for partial volume averaging was developed and validated in a study with phantoms. The program was then used to determine the tracheal cross-sectional area of 30 normal children who ranged in age from four months to 18 years. CT-derived cross sections were correlated with age, height, weight, and body-surface area, and they were compared with findings of published clinical and post-mortem studies. CT cross-sectional areas ranged from 20 to 275 mm/sup 2/, varied by as much as 22% at the three different tracheal levels studied, and appeared to correlate most closely with body height. CT-derived tracheal cross-sectional areas are quite similar to those in published reports of postmortem and clinical studies. Measurements of tracheal cross section by CT may prove useful in quantitating tracheal compromise by intrinsic or extrinsic causes.

1983-10-01

229

Total skin electron beam therapy in mycosis fungoides. Evaluation of a technique for deceleration of electron beam energy and clinical study  

Energy Technology Data Exchange (ETDEWEB)

The studies using phantoms confirmed that the reduction of electron beam energy and minimization of X-ray contamination could be achieved when electron beam was interposed by an acrylic plate placed 20 cm anterior to a patient. Four patients of mycosis fungoides were treated with 8 MeV electron beam of a linear accelerator at UOEH Hospital from October 1981 to December 1986. Two of them were treated with this technique by placing 2 cm thick acrylic plate anterior to the patients and satisfactory results were obtained. Cutaneous lesions subsided remarkably with the dosage of 2000 cGy given in 2 months. Leucopenia due to bone marrow suppression was mild and the patients tolerated the treatment well.

1988-08-01

230

Total skin electron beam therapy in mycosis fungoides  

International Nuclear Information System (INIS)

The studies using phantoms confirmed that the reduction of electron beam energy and minimization of X-ray contamination could be achieved when electron beam was interposed by an acrylic plate placed 20 cm anterior to a patient. Four patients of mycosis fungoides were treated with 8 MeV electron beam of a linear accelerator at UOEH Hospital from October 1981 to December 1986. Two of them were treated with this technique by placing 2 cm thick acrylic plate anterior to the patients and satisfactory results were obtained. Cutaneous lesions subsided remarkably with the dosage of 2000 cGy given in 2 months. Leucopenia due to bone marrow suppression was mild and the patients tolerated the treatment well. (author).

231

The effect of patient positioning aids on PET quantification in PET/MR imaging  

British Library Electronic Table of Contents (United Kingdom)

Objectives Clinical PET/MR requires the use of patient positioning aids to immobilize and support patients for the duration of the combined examination. Ancillary immobilization devices contribute to overall attenuation of the PET signal, but are not detected with conventional MR sequences and, hence, are ignored in standard MR-based attenuation correction (MR-AC). We report on the quantitative effect of not accounting for the attenuation of patient positioning aids in combined PET/MR imaging. Methods We used phantom and patient data acquired with positioning aids on a PET/CT scanner (Biograph 16, HI-REZ) to mimic PET/MR imaging conditions. Reference CT-based attenuation maps were generated from measured (original) CT transmission images (origCT-AC). We also created MR-like attenuation map...

2011-01-01

232

Somatic radiation risk in different mammography techniques  

International Nuclear Information System (INIS)

By measuring organ doses with TLD at an Alderson-Rando-phantom it was tested to evaluate the somatic risk for mammographies. Similarly as the genetic risk can be expressed by the genetic significant dose, the somatic risk can be expressed by the somatic significant dose index. The measurement results of the mammography show a large deviation of almost one power of ten with dependence of the chosen technique. In conventional xeroradiography and recording technique with foilless film the somatic radiation risk is the highest. By using amplifying foils in combination with high-sensitive films it is relatively small. Unfortunately the magnitude of the somatic risk in the different mammography techniques is in the ratio reciprocal to the corresponding image quality. At the time being the most favourable technique is mammography with a soft rastering method, although the xeromammography with additional high aluminium-filtering is a further alternative with respect to ...

1981-01-01

233

Somatic and genetic radiation exposure of the patient in digital subtraction angiography (DSA)  

International Nuclear Information System (INIS)

The somatic and genetic radiation exposure of patients undergoing Digital Subtraction Angiography (DSA) and traditional Film Arteriography (FA) of cranial, cervical, thoracic and abdominal vascular territories are compared. The radiation doses absorbed within the critical organs - red bone marrow, lung, thyroid gland and female breast - and in the gonads were measured using an anthropomorphic Alderson phantom. A Somatic Dose Index was calculated in order to estimate the somatic radiation risk. The somatic radiation exposure depends upon the location of the critical organs with respect to the entrance site of the x-ray beam, and can be reduced by an appropriate choice of the angiographic projection. Under this condition, the radiation exposure of the patient during DSA can be lower than during FA. For renal DSA an a.p. projection, the use of an abdominal compression device and careful caudal shielding of the field are advocated. (orig.).

1986-01-01

234

Sex Differences in Pain and Psychological Functioning in Persons With Limb Loss  

British Library Electronic Table of Contents (United Kingdom)

Sex differences in pain are frequently reported in the literature. However, less is known about possible sex differences in the experience of pain secondary to a disability. The current study explored these issues in persons with limb loss (n = 335, 72% men) who were recruited as part of a postal survey. Participants provided ratings of phantom limb pain (PLP), residual limb pain (RLP), and general pain intensity. Participants also completed measures of pain-related interference, catastrophizing, coping, and beliefs. Results indicated that a greater proportion of males than females (86% vs 77%, respectively) reported the presence of PLP; however, this difference was no longer prominent when cause of limb loss was controlled. No sex differences were found in the presence of RLP, or in avera...

2010-01-01

235

Radioexposure of children in cranial examinations with new-generation CT equipment  

Energy Technology Data Exchange (ETDEWEB)

Using phantoms of children simulating a child of 6 months of age and another one aged 6 years, the authors measured the amount of radioexposure of the lens of the eye, the thyroid and of the gonads. The two computer tomographs Somatom SF and Tomoscan 300 under examination, produced radiodoses of comparable magnitudes. Both devices allow additional examination techniques of particularly high economy. It was found that in cranial CT the exposure of the lens to radiation is generally below 1 R if the orbitae are not situated in the plane of section. If a distance of 2-3 cm is maintained from the orbitae, the dose remains below 0.5 R. Protecting the gonads is meaningful in a 6-year-old boy, whereas covering-up of the thyroid reduced the dose only slightly.

1983-04-01

236

Radiation exposure to patients during hepatic interventional procedure  

International Nuclear Information System (INIS)

Objective: To investigate the X-ray radiation dose patients dealt with the hepatic intervention. Methods: Thermoluminescence and tissue-equivalent anthropomorphic phantom were used to measure the X-ray radiation dose in patients dealt with the hepatic intervention in 85 patients. Results: The peak skin dose in the patients who accepted hepatic intervention was from 179.95 to 1759.00 mGy, effective dose approached 29.22 mSv (male), 29.27 mSv (female). Conclusion: Hepatic intervention is now regarded as an important therapeutic method for liver cancer. However, the patients were exposed to too much X-ray radiation during interventional procedures. Some more effective protection should be taken to decrease the X-ray radiation dose accepted by patients. (authors)

2005-05-01

237

Quantitative bone scintigraphy. A methodological evaluation in prostate cancer  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To evaluate a simple method for quantification of focal activity in bone scintigraphy (BS). Material and methods: The gamma camera was calibrated using a phantom. Quantitative bone scintigraphy (QBS) was performed on 11 men recently diagnosed with prostate cancer (PCa), for whom routine BS showed involvement of the skeleton. Following endocrine therapy for 4 to 8 months, a second QBS was performed. Changes in QBS values were then compared to changes in serum levels of prostate-specific antigen (PSA). Results: PSA response indicating regression of PCa was accompanied by a decrease in the QBS value in 8 of the 11 patients. The overall mean error of the QBS values was 15%. conclusion: QBS according to this method is a relatively simple procedure that might contribute to objective evaluation of therapeutic effects in skeletal metastases, although its validity must be tested in a larger clinical material.

2000-03-01

238

Quantitative bone scintigraphy. A methodological evaluation in prostate cancer  

International Nuclear Information System (INIS)

Purpose: To evaluate a simple method for quantification of focal activity in bone scintigraphy (BS). Material and methods: The gamma camera was calibrated using a phantom. Quantitative bone scintigraphy (QBS) was performed on 11 men recently diagnosed with prostate cancer (PCa), for whom routine BS showed involvement of the skeleton. Following endocrine therapy for 4 to 8 months, a second QBS was performed. Changes in QBS values were then compared to changes in serum levels of prostate-specific antigen (PSA). Results: PSA response indicating regression of PCa was accompanied by a decrease in the QBS value in 8 of the 11 patients. The overall mean error of the QBS values was 15%. conclusion: QBS according to this method is a relatively simple procedure that might contribute to objective evaluation of therapeutic effects in skeletal metastases, although its validity must be tested in a larger clinical material

2000-03-01

239

Quantitative Computed Tomography (QCT) of vertebral spongiosa. Evaluation of a possible method for managment of postmenopausal osteoporosis (PMO)  

International Nuclear Information System (INIS)

A Quantitative Computed Tomography (QCT) method, simplifying the well-known technique proposed by Genant (1982) and applied to a standard third generation whole body CT scanner is described. This technique was applied in the measurement of the trabecular bone which has high sensitivity for metabolic changes. The BMC (Bone Mineral Content) measured in different groups of subjects (healthy postmenopausal patients versus women with postmenopausal osteoporosis) showed a highly significant difference (p<0.001). The precision of repositioning (coefficient of variation 1.8% to 2.3%, obtained in healty male patients) and the good, linear relationship computed from the phantom values, minimize measurement errors. Since this method is quickly applied and involves low-dose radiation-exposure, it could be introduced in the clinical study of metabolic bone diseases.

1987-01-01

240

Preparation and dosimetry of radiotherapeutic particles for arthropaties; Preparacion y dosimetria de particulas radioterapeuticas para artropatias  

Energy Technology Data Exchange (ETDEWEB)

It was developed a new formulation of macro aggregates of Samarium 153 ({sup 153} Sm-MH) for the arthropaties treatment. The radio pharmaceutic was prepared by reaction of Samarium 153 chloride (SmCl{sub 3}) in aqueous environment with sodium boron hydride in NaOH 0.5 N. The microscopic analysis shown that the particles have an average size of 4% m (range 1-14 {mu} m). The velocity of sedimentation was 0.008 cm/min with high stability in vitro in human serum. The biological studies in healthy rabbits, shown that the complex is retained inside the articulation still eight days after of the administration of the radiopharmaceutical. Likewise, it is presented the data of absorbed dose in the different target organs, which was determined by thermoluminescent dosimetry (TLD) through the use of a REMCAL phantom (radiation equivalent manikin calibration). (Author)

1999-07-01

241

Preamputation Pain and Acute Pain Predict Chronic Pain After Lower Extremity Amputation  

British Library Electronic Table of Contents (United Kingdom)

Although previous research suggests that preamputation pain is a risk factor for pain after amputation, little is known about the association between acute postsurgical pain and chronic amputation-related pain. The current prospective study examined the associations of preamputation pain and acute postamputation pain with chronic amputation-related pain. The sample consisted of patients with lower limb amputation (N = 57) who provided both preamputation and postamputation data during a 2-year study period. Preamputation pain intensity and duration were assessed before amputation; acute phantom limb pain (PLP) and residual limb pain (RLP) intensity were assessed on postsurgical days 4 and 5. Acute PLP intensity was the only significant independent predictor of chronic PLP intensity at 6 and...

2007-01-01

242

Portal localization images using computed radiography for high-energy electron beam therapy  

Energy Technology Data Exchange (ETDEWEB)

Portal localization images for high-energy electron beam therapy are necessary to confirm the treatment field by comparing them with a simulation image obtained before treatment or portal verification images after treatment. In this study, portal localization images were acquired using the computed radiography (CR) system and bremsstrahlung X-rays generated in the electron beam irradiations. All images obtained with phantom and the irradiations of in the electron energy of 8, 10, 12 and 15 MeV were feasible for clinical use. The CR system used in this study included general diagnostic imaging cassette and storage phosphor plate, but none of other special devices. The system can usually supply portal localization images, which maintains the quality assurance of high-energy electron beam therapy. (author)

2002-09-01

243

Photon beam modelling with Pinnacle3 Treatment Planning System for a Rokus M Co-60 Machine  

International Nuclear Information System (INIS)

The basic relationships of the convolution/superposition dose calculation technique are reviewed, and a modelling technique that can be used for obtaining a satisfactory beam model for a commercially available convolution/superposition-based treatment planning system is described. A fluence energy spectrum for a Co-60 treatment machine obtained from a Monte Carlo simulation was used for modelling the fluence spectrum for a Rokus M machine. In order to achieve this model we measured the depth dose distribution and the dose profiles with a Wellhofer dosimetry system. The primary fluence was iteratively modelled by comparing the computed depth dose curves and beam profiles with the depth dose curves and crossbeam profiles measured in a water phantom. The objective of beam modelling is to build a model of the primary fluence that the patient is exposed to, which can then be used for the calculation of the dose deposited in the patient. (authors)

244

Photoacoustic imaging using an ultrasonic Fresnel zone plate transducer  

International Nuclear Information System (INIS)

A photoacoustic (PA) imaging system based on an ultrasonic Fresnel zone plate (FZP) transducer is developed for the purpose of imaging biological tissue. This FZP transducer has a two-zone negative zone plate piezoelectric material pattern, and an optical fibre is integrated with the transducer on the symmetric axis of the zone plates to deliver laser pulses to the sample. The focal characteristic of the FZP transducer is analysed by theoretical prediction and experimental measurement, and the measured results are in good agreement with the predicted results. The limited-field back-projection deconvolution algorithm combined with the coherence-factor weighting technique is used to reconstruct the optical absorption distribution. The experiments were performed with phantoms and the blood vessels of chicken embryo chorioallantoic membrane. The results demonstrate that PA imaging using the FZP transducer has the ability to image biological tissue and has potential ...

2008-05-07

245

Organ doses received by atomic bomb survivors during radiological examinations at the Radiation Effects Research Foundation  

Energy Technology Data Exchange (ETDEWEB)

When evaluating the risks of oncogenesis and cancer mortality following exposure to the radiations of the atomic bombs (A-bombs), the medical X-ray doses received by the A-bomb survivors must also be estimated and considered. Using a human phantom, dosimetry was performed to estimate the X-ray doses received by A-bomb survivors during medical examinations at the Radiation Effects Foundation (RERF) as part of the long-term follow-up on the Adult Health Study (AHS). These examinations have been estimated to represent nearly 45% of the survivors' cumulative medical irradiation dose. Doses to the salivary glands, thyroid gland, lung, breast, stomach and colon were measured using thermoluminescent dosemeters. The results, which are reported here, will aid in estimating organ doses received by individual AHS participants. (Author).

1991-08-01

246

Organ doses received by atomic bomb survivors during radiological examinations at the Radiation Effects Research Foundation  

International Nuclear Information System (INIS)

When evaluating the risks of oncogenesis and cancer mortality following exposure to the radiations of the atomic bombs (A-bombs), the medical X-ray doses received by the A-bomb survivors must also be estimated and considered. Using a human phantom, dosimetry was performed to estimate the X-ray doses received by A-bomb survivors during medical examinations at the Radiation Effects Foundation (RERF) as part of the long-term follow-up on the Adult Health Study (AHS). These examinations have been estimated to represent nearly 45% of the survivors' cumulative medical irradiation dose. Doses to the salivary glands, thyroid gland, lung, breast, stomach and colon were measured using thermoluminescent dosemeters. The results, which are reported here, will aid in estimating organ doses received by individual AHS participants. (Author).

1991-01-01

247

Minimizing radiation dose to patient and staff during fluoroscopic, nasoenteral tube insertions  

Energy Technology Data Exchange (ETDEWEB)

Since the fluoroscopic image during nasoenteral tube placements is used for guidance and not for diagnosis, a lower contrast image with increased quantum mottle can be easily tolerated. The three methods to reduce the radiation dose rate investigated consisted of removing camera from the image intensifier output phosphor, and setting the fluoroscopic mA to the minimum value so that the kVp could be maximized. Fluoroscopic frozen video frames of a clinical tube insertion comparing the images with and without the dose-saving techniques are presented. Measurements of the radiation dose rates using a Plexiglas phantom show that the dose for patient and staff during fluoroscopic-guided nasoenteral tube placements can be reduced by over a factor of 10 without significantly adversely affecting the actual placement procedure. (author).

1992-02-01

248

Efficiency of a lead-containing tie for radiation protection of the thyroid gland  

Energy Technology Data Exchange (ETDEWEB)

During fluoroscopy the examiner is usually protected by a radiation-reducing body shield, leaving the thyroid unprotected. The fact that the thyroid is located in a region of the neck usually covered by the shirt collar led to the idea of designing a tie with lead core, providing easy and ''decorative'' reduction of the radiation dose. Sonographic examinations were carried out in 20 volunteers (10 men, 10 women) to determine the size of the gland and its coverage by such a tie. The reduction of the surface and organ dose was assessed using film dosimetry with scattered radiation, the body of the examiner being simulated by an Alderson phantom. On average 88% of the thyroid gland surface area was covered. Surface dose was reduced to 1%, and organ dose to 10% of the value without the protection tie. (Author).

1992-11-01

249

Efficiency of a lead-containing tie for radiation protection of the thyroid gland  

International Nuclear Information System (INIS)

During fluoroscopy the examiner is usually protected by a radiation-reducing body shield, leaving the thyroid unprotected. The fact that the thyroid is located in a region of the neck usually covered by the shirt collar led to the idea of designing a tie with lead core, providing easy and ''decorative'' reduction of the radiation dose. Sonographic examinations were carried out in 20 volunteers (10 men, 10 women) to determine the size of the gland and its coverage by such a tie. The reduction of the surface and organ dose was assessed using film dosimetry with scattered radiation, the body of the examiner being simulated by an Alderson phantom. On average 88% of the thyroid gland surface area was covered. Surface dose was reduced to 1%, and organ dose to 10% of the value without the protection tie. (Author).

250

Digital radiography of pulmonary abnormalities using Fuji computed radiography (FCR)  

Energy Technology Data Exchange (ETDEWEB)

Fuji computed radiography (FCR) utilizing imaging plates stimulated by a scanning lazer has been developed in Japan and come to be widely available in diagnostic radiology. This system is advantageous because many processed images can be obtained with a single exposure. However, no reports have been published on the exact conditions necessary under which the FCR image processing method will produce improved visibility of pulmonary abnormal shadows on chest radiographs. In this report, chest FCR images obtained from 50 patients were analyzed, and the best practical image processing conditions were determined for each pathological state. Fundamental analysis was also performed for spatial and contrast resolution with FUNK chart and Burger's phantom using various thickness of acryl plate. Ninety processing images per exposure were analyzed, and the best practical conditions were determined. (author).

1991-12-01

251

Digital radiography of pulmonary abnormalities using Fuji computed radiography (FCR)  

International Nuclear Information System (INIS)

Fuji computed radiography (FCR) utilizing imaging plates stimulated by a scanning lazer has been developed in Japan and come to be widely available in diagnostic radiology. This system is advantageous because many processed images can be obtained with a single exposure. However, no reports have been published on the exact conditions necessary under which the FCR image processing method will produce improved visibility of pulmonary abnormal shadows on chest radiographs. In this report, chest FCR images obtained from 50 patients were analyzed, and the best practical image processing conditions were determined for each pathological state. Fundamental analysis was also performed for spatial and contrast resolution with FUNK chart and Burger's phantom using various thickness of acryl plate. Ninety processing images per exposure were analyzed, and the best practical conditions were determined. (author).

1991-01-01

252

Affective Distress and Amputation-Related Pain Among Older Men with Long-Term, Traumatic Limb Amputations  

British Library Electronic Table of Contents (United Kingdom)

Psychological distress and postamputation pain were investigated in a sample of 582 males with long-term limb amputations (mean time since amputation 639.3 months, standard deviation 166.1; range 240-784 months). Prevalence of significant depressive symptoms (Hospital Anxiety and Depression Scale [HADS]-D score?8) was 32.0%, and 34.0% of respondents met the screening criterion for clinical anxiety (HADS-A score?8). Nearly one quarter (24.6%) of respondents reported significant post-traumatic psychological stress symptoms (Impact of Event Scale scores?35). In total, 87.8% experienced either phantom or residual limb pain. Affective distress scores differed according to the respondents' type of pain experience. Respondents who experienced residual limb pain reported significantly hig...

2006-01-01

253

A novel method for quantifying scanner instability in fMRI  

British Library Electronic Table of Contents (United Kingdom)

Abstract A method was developed to quantify the effect of scanner instability on functional MRI data by comparing the instability noise to endogenous noise present when scanning a human. The instability noise was computed from agar phantom data collected with two flip angles, allowing for a separation of the instability from the background noise. This method was used on human data collected at four 3 T scanners, allowing the physiological noise level to be extracted from the data. In a -well-operating- scanner, the instability noise is generally less than 10% of physiological noise in white matter and only about 2% of physiological noise in cortex. This indicates that instability in a well-operating scanner adds very little noise to functional MRI results. This new method allows researcher...

2011-01-01

254

A compensating method of an imaging plate response to clinical proton beams  

Energy Technology Data Exchange (ETDEWEB)

For charged particle irradiations, the response of an imaging plate (IP) changes around the Bragg peak. Therefore, an appropriate compensation is necessary for the evaluation of dose distribution formed by charged particles such as protons. In this paper, the response of IPs to clinical proton beams is investigated. An experimentally-obtained depth-dose distribution (an ordinary Bragg curve) by a silicon semiconductor detector (SSD) is employed to evaluate the compensation factors as a function of proton penetrating depth, i.e. residual range. A typical dose distribution in a water phantom formed by an L-shaped bolus is measured by IPs and corrected by using the information of those compensation factors; the residual proton range is successfully calculated by the pencil beam algorithm at an arbitrary point. The results show a good agreement with the measurements by the SSD within the rms error of 3.0%.

2002-04-01

255

Verification of zinc injection applicability to Japanese BWRs  

Energy Technology Data Exchange (ETDEWEB)

The verification test program on zinc injection applicability to Japanese BWRs was started in 1997. Laboratory tests using high temperature water loops under BWR reactor water conditions are in progress. This paper is an interim report on results obtained so far. Co-58 and Zn-65 were simultaneously used in the Co radioactivity buildup test to evaluate zinc injection suppression effects towards cobalt deposition on pre-oxidized stainless steel. The following results were obtained. The Co deposition was suppressed effectively by Zn injection, even when there was a pre-oxide film. For the test piping that had the pre-oxide film formed under the NWC (normal water chemistry) condition, when soaked under the HWC (hydrogen water chemistry) condition a large amount of Co-58 was taken into a small part of the inner layer. The distribution ratio of Co-58 in the inner layer and outer layer of the oxide film was almost the same for both the pre-oxidized test piping and the non ...

2002-07-01

256

Recent Korean R&D in Satellite Communications  

Science.gov (United States)

The R&D in satellite communications in Korea has been driven mainly by KCC (Korea Communications Commission) but in a small scale compared to Korea space development program organized by MEST (Ministry of Education, Science and Technology). Public and civilian satcom sector R&D has been led mainly by ETRI with small/medium companies contrary to rare investment in private sector while military sector R&D has been orchestrated by ADD with defense industry. By the COMS (Communication, Ocean and Meteorological Satellite) experimental Ka-band payload, Korea pursues a space qualification of own technology for national infrastructure evolution as well as industrialization of space R&D results. Once COMS launched and space qualified in 2009, subsequent application experiments and new technology R&D like UHDTV will entail service and industry promotion. The payload technology is expected for the next Korean commercial satellites or for new OBP satellites. The COMS ground ...

2009-01-01

257

Government policy and the development of electric vehicles in Japan  

International Nuclear Information System (INIS)

The aim of this paper is to analyse the role that the Japanese Government has played in the development of alternatives to conventional vehicles, the effect of government programmes, and the importance of technical flexibility in government support schemes. The focus is on battery-powered electric vehicles (BPEVs), hybrid electric vehicles (HEVs), and fuel cell electric vehicles. The effects of government policy and the process of innovation are analysed from a systems approach drawing on the literature regarding technical change and innovation. The whole chain of government support, including the context in which these different policies have been implemented since the early 1970s, is studied. The Japanese Government has adopted a comprehensive strategy including R and D, demonstration programmes and market support guided by long-term strategic plans. The role of the Government has been that of a conductor in the development process supplying ...

2006-03-01

258

Goals and activities of the JICA technical cooperation project on reduction of seismic risk in Romania  

International Nuclear Information System (INIS)

Japan International Cooperation Agency (JICA) Technical Cooperation Project on Reduction of Seismic Risk for Buildings and Structures started in Romania on October 1, 2002. The aim of the Project is to strengthen the capacity of earthquake disaster related activities in Romania. The Project approval is the result of four years of intensive efforts made by professionals from Technical University of Civil Engineering Bucharest (UTCB), Ministry of Transport, Constructions and Tourism (MTCT), Romania, National Building Research Institute (INCERC) Bucharest, JICA, Building Research Institute (BRI), Tsukuba, and National Institute for Land, Infrastructure and Management (NILIM), Tsukuba, Japan. The duration of the Project is five years. The implementing agency is the National Center for Seismic Risk Reduction (NCSRR) as a public institution of national interest under MTCT. The activities are carried out by NCSRR in partnership with UTCB and INCERC. During the Project period, 29 young ...

2007-04-26

259

Using a photon phase-space source for convolution/superposition dose calculations in radiation therapy  

International Nuclear Information System (INIS)

For a given linac design, the dosimetric characteristics of a photon beam are determined uniquely by the energy and radial distributions of the electron beam striking the x-ray target. However, in the usual commissioning of a beam from measured data, a large number of variables can be independently tuned, making it difficult to derive a unique and self-consistent beam model. For example, the measured dosimetric penumbra in water may be attributed in various proportions to the lateral secondary electron range, the focal spot size and the transmission through the tips of a non-divergent collimator; the head-scatter component in the tails of the transverse profiles may not be easy to resolve from phantom scatter and head leakage; and the head-scatter tails corresponding to a certain extra-focal source model may not agree self-consistently with in-air output factors measured on the central axis. To reduce the number of adjustable variables in beam modelling, we replace ...

2005-09-07

260

Spectral sensitivity study of dose distributions for a commercial convolution/superposition algorithm  

International Nuclear Information System (INIS)

The focus of this study is to validate whether the sensitivity of dose distribution following the interface of different media can be used to distinguish between small variations of photon energy spectra in the context of the convolution/superposition algorithm in the polyenergetic implementation (Philips Pinnacle"3, ADAC Laboratories, Milpitas, CA). Calculations were performed in homogeneous water and heterogeneous lung/water phantoms. Spectra were generated, in which the weights of the low-, medium- and high-energy components were adjusted sequentially. The heterogeneity correction factor CF_l_u_n_g, the D_2_0/D_1_0 ratio for homogeneous water and logarithmic derivative in buildup region LD_b_u_i_l_d_u_p were assessed for their relative ability to discriminate between different spectra for various field sizes. In accordance with another study (Charland et al 2004), the superior discrimination ability of the CF_l_u_n_g and LD_b_u_i_l_d_u_p tests over the ...

2004-09-21

261

Pulmonary nodule detection of chest phantom with CRT images; Comparison with conventional radiography (film-screen system) and FCR hardcopy  

Energy Technology Data Exchange (ETDEWEB)

Conventional Radiography, Fuji Computed Radiography (FCR) hardcopy and CRT images were evaluated about the detectability of pulmonary nodule using the chest phantom. Conventional and digitized chest radiographs (FCR) were used, including 45 normal cases and 45 abnormal cases with a variety pulmonary nodule. Observer performance tests were conducted to compare the effects on diagnostic accuracy of Conventional Radiography, FCR hardcopy and CRT images, and diagnostic accuracy was determined with receiver operating characteristic (ROC) analysis. ROC study was performed in which six radiologists were asked to locate nodule on three modalities. Two CRT monitors were used to observed CRT images. The left side CRT monitor was divided into two parts and displayed two images which were done as same image processing as FCR hardcopy. The right side CRT monitor was divided into four parts and displayed four images as a subsidiary diagnosis. The upper two images were displayed ...

1989-08-01

262

Pulmonary nodule detection of chest phantom with CRT images  

International Nuclear Information System (INIS)

Conventional Radiography, Fuji Computed Radiography (FCR) hardcopy and CRT images were evaluated about the detectability of pulmonary nodule using the chest phantom. Conventional and digitized chest radiographs (FCR) were used, including 45 normal cases and 45 abnormal cases with a variety pulmonary nodule. Observer performance tests were conducted to compare the effects on diagnostic accuracy of Conventional Radiography, FCR hardcopy and CRT images, and diagnostic accuracy was determined with receiver operating characteristic (ROC) analysis. ROC study was performed in which six radiologists were asked to locate nodule on three modalities. Two CRT monitors were used to observed CRT images. The left side CRT monitor was divided into two parts and displayed two images which were done as same image processing as FCR hardcopy. The right side CRT monitor was divided into four parts and displayed four images as a subsidiary diagnosis. The upper two images were displayed ...

1989-01-01

263

Monte Carlo evaluation of the AAA treatment planning algorithm in a heterogeneous multilayer phantom and IMRT clinical treatments for an Elekta SL25 linear accelerator  

International Nuclear Information System (INIS)

The Anisotropic Analytical Algorithm (AAA) is a new pencil beam convolution/superposition algorithm proposed by Varian for photon dose calculations. The configuration of AAA depends on linear accelerator design and specifications. The purpose of this study was to investigate the accuracy of AAA for an Elekta SL25 linear accelerator for small fields and intensity modulated radiation therapy (IMRT) treatments in inhomogeneous media. The accuracy of AAA was evaluated in two studies. First, AAA was compared both with Monte Carlo (MC) and the measurements in an inhomogeneous phantom simulating lung equivalent tissues and bone ribs. The algorithm was tested under lateral electronic disequilibrium conditions, using small fields (2x2 cm"2). Good agreement was generally achieved for depth dose and profiles, with deviations generally below 3% in lung inhomogeneities and below 5% at interfaces. However, the effects of attenuation and scattering close to the bone ribs were not ...

2007-05-01

264

Maximum imaging depth of two-photon autofluorescence microscopy in epithelial tissues  

Science.gov (United States)

Endogenous fluorescence provides morphological, spectral, and lifetime contrast that can indicate disease states in tissues. Previous studies have demonstrated that two-photon autofluorescence microscopy (2PAM) can be used for noninvasive, three-dimensional imaging of epithelial tissues down to approximately 150 ?m beneath the skin surface. We report ex-vivo 2PAM images of epithelial tissue from a human tongue biopsy down to 370 ?m below the surface. At greater than 320 ?m deep, the fluorescence generated outside the focal volume degrades the image contrast to below one. We demonstrate that these imaging depths can be reached with 160 mW of laser power (2-nJ per pulse) from a conventional 80-MHz repetition rate ultrafast laser oscillator. To better understand the maximum imaging depths that we can achieve in epithelial tissues, we studied image contrast as a function of depth in tissue phantoms with a range of relevant optical properties. The ...

2011-02-01

265

Feasibility of delivering grid therapy using a multileaf collimator  

International Nuclear Information System (INIS)

The feasibility of using a multileaf collimator (MLC) for grid therapy is demonstrated in this study. Grids with the projected field openings of 10 mmx10 mm and 5 mmx5 mm were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid water phantom and compared to those of Cerrobend grid collimators of similar hole sizes and hole separations. At the depth of maximum dose (d_m_a_x), the valley-to-peak dose ratios of the MLC grids were found to be about 11% and 19% for the respective 10 mmx10 mm and 5 mmx5 mm grid openings, and those of the corresponding grid blocks were about 15% and 20%. To quantify the dose contributed by transmission in the blocked areas due to the limited leaf thickness, Monte Carlo simulations (based on convolution/superposition method) were performed to calculate the doses in the solid water phantom using an ideal MLC with no leakage and perfect divergence in both ...

2006-01-01

266

Dosimetric evaluation of multi-pattern spatially fractionated radiation therapy using a multi-leaf collimator and collapsed cone convolution superposition dose calculation algorithm  

International Nuclear Information System (INIS)

Purpose: In this paper, we present an alternative to the originally proposed technique for the delivery of spatially fractionated radiation therapy (GRID) using multi-leaf collimator (MLC) shaped fields. We employ the MLC to deliver various pattern GRID treatments to large solid tumors and dosimetrically characterize the GRID fields. Methods and materials: The GRID fields were created with different open to blocked area ratios and with variable separation between the openings using a MLC. GRID designs were introduced into the Pinnacle"3 treatment planning system, and the dose was calculated in a water phantom. Ionization chamber and film measurements using both Kodak EDR2 and Gafchromic EBT film were performed in a SolidWater phantom to determine the relative output of each GRID design as well as its spatial dosimetric characteristics. Results: Agreement within 5.0% was observed between the Pinnacle"3 predicted dose distributions and the ...

2009-10-01

267

Digital subtraction angiography (DSA) using Fuji computed radiography (FCR)  

International Nuclear Information System (INIS)

A vessel phantom suitable for evaluation of spatial and contrast resolution of FCRDSA (Fuji Computed Radiography, digital subtraction angiography) has been developed and used for determining resolution. The effects of iodine concentration, low dose exposure, and acryl thickness on the resolution were evaluated in FCRDSA, and FCRDSA images were compared with film substraction with use of this phantom. It has been proven that limitation of resolution of FCRDSA was 5 % 1 mm and about 1/4 dose exposure compared with conventional film exposure was clinically acceptable. Dye dilution method was useful to determine a program of IVDSA with imaging plate. It has been proven that time to appearance and time to peak of time-concentration curve of dye dilution method closely correlate to time to appropriate image of DSA in the neck, the chest, and the abdomen. 106 cases of IVDSA and 130 cases of IADSA using FCR in Tohoku University Hospital from January ...

1984-12-01

268

Accuracy of the convolution/superposition dose calculation algorithm at the condition of electron disequilibrium  

International Nuclear Information System (INIS)

Using Monte Carlo simulation and the convolution/superposition algorithm, this work examines percent depth dose curves of the central axis in an acrylic phantom (20x20x20 cm"3) with variously sized air cavities (20x20x1.0, 20x20x2.0, 20x20x3.0, 20x20x4.0 and 20x20x4.95 cm"3 for study of longitudinal electron disequilibrium (ED) and 3.6x3.6x4.95, 4.5x4.5x4.95, 5.4x5.4x4.95 and 20x20x4.95 cm"3 for study of lateral ED). Radiochromic film samples are also measured to verify the Monte Carlo results. The Monte Carlo simulation is performed using OMEGA/BEAM and DOSXYZ codes, and the convolution/superposition calculation relies on an ADAC commercial treatment planning system. Underestimating the dose kernel expansion leads to overestimating the dose of what was found in the air cavity of ED using the convolution/superposition algorithm. Consequently, the dose in the rebuild-up region is influenced. The influenced region is on the acrylic phantom ...

2002-12-01

269

Accuracy of calculations for stereotactic radiotherapy of the lung. Comparison of dose calculation algorithms  

International Nuclear Information System (INIS)

The purpose of this study is to evaluate the accuracy of dose calculations by three algorithms. Depth dose, OPF (Output Factor) and dose profiles were measured in a heterogeneous phantom. These values were also calculated by three algorithms of the Batho power law (BPL), Equivalent-Tissue Air Ratio (ETAR) and Convolution superposition (CS). The data were obtained for 4, 6 and 10 MV photon beams with a linear accelerator (Varian 21EX). Field size ranged from 3 x 3 cm"2 to 10 x 10 cm"2. Dose profiles of beam penumbra were also measured by a 0.125 ml ionization chamber at the point of 8, 13 and 18 cm from the surface of the phantom at intervals of 1 mm. Differences between measured and calculated depth doses were within 2% in BPL and CS, but depth doses were overestimated in ETAR. OPFs were also overestimated with the error of more than 4% in ETAR. Absorbed dose calculated by CS were in agreement with the values measured by the ionization chamber. ...

2004-12-01

270

A cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: experimental study based on an agar phantom  

Energy Technology Data Exchange (ETDEWEB)

A great deal of current research is directed to finding a way to minimize thermal injury in the esophagus during radiofrequency catheter ablation of the atrium. A recent clinical study employing a cooling intraesophageal balloon reported a reduction of the temperature in the esophageal lumen. However, it could not be determined whether the deeper muscular layer of the esophagus was cooled enough to prevent injury. We built a model based on an agar phantom in order to experimentally study the thermal behavior of this balloon by measuring the temperature not only on the balloon, but also at a hypothetical point between the esophageal lumen and myocardium (2 mm distant). Controlled temperature (55 {sup 0}C) ablations were conducted for 120 s. The results showed that (1) the cooling balloon provides a reduction in the final temperature reached, both on the balloon surface and at a distance of 2 mm; (2) coolant temperature has a significant effect on the temperature ...

2008-02-21

271

The requirement for sodium as a micronutrient by species having the c(4) dicarboxylic photosynthetic pathway.  

Science.gov (United States)

Six species having characteristics of plants with the C(4) dicarboxylic photosynthetic pathway, Echinochloa utilis L. Ohwi et Yabuno (Japanese millet), Cynodon dactylon L. (Bermuda grass), Kyllinga brevifolia Rottb., Amaranthus tricolor L. cv. Early splendour, Kochia childsii Hort., and Portulaca grandiflora Hook (rose moss), responded decisively to 0.1 milliequivalent per liter NaCl supplied to their culture solutions initially containing less than 0.08 microequivalent per liter Na. Chlorosis and necrosis occurred in leaves of plants not receiving sodium. Portulaca failed to set flower in the sodium-deficient cultures. Under similar conditions Poa pratensis L. (Kentucky blue grass) having characteristics of the C(3) photosynthetic pathway made normal growth and did not respond to the addition of sodium. It is concluded from these results and previously reported work that sodium is generally essential for species having the C(4) pathway but not for species with the ...

1972-05-01

272

The Requirement for Sodium as a Micronutrient by Species Having the C4 Dicarboxylic Photosynthetic Pathway  

Science.gov (United States)

Six species having characteristics of plants with the C4 dicarboxylic photosynthetic pathway, Echinochloa utilis L. Ohwi et Yabuno (Japanese millet), Cynodon dactylon L. (Bermuda grass), Kyllinga brevifolia Rottb., Amaranthus tricolor L. cv. Early splendour, Kochia childsii Hort., and Portulaca grandiflora Hook (rose moss), responded decisively to 0.1 milliequivalent per liter NaCl supplied to their culture solutions initially containing less than 0.08 microequivalent per liter Na. Chlorosis and necrosis occurred in leaves of plants not receiving sodium. Portulaca failed to set flower in the sodium-deficient cultures. Under similar conditions Poa pratensis L. (Kentucky blue grass) having characteristics of the C3 photosynthetic pathway made normal growth and did not respond to the addition of sodium. It is concluded from these results and previously reported work that sodium is generally essential for species having the C4 pathway but not for species with the C3 ...

1972-01-01

273

Serum Osteocalcin/Bone-Specific Alkaline Phosphatase Ratio Is a Predictor for the Presence of Vertebral Fractures in Men with Type 2 Diabetes  

British Library Electronic Table of Contents (United Kingdom)

We examined whether or not BMD or bone markers were useful for assessing the risk of vertebral fractures in 248 Japanese men with type 2 diabetes. We analyzed the relationships between bone markers (osteocalcin [OC], bone-specific alkaline phosphatase [BAP], urinary N-terminal cross-linked telopeptide of type-I collagen) or BMD and HbA1c, urinary C-peptide, insulin-like growth factor-I (IGF-I), parathyroid hormone, 1,25(OH)2 vitamin D, and the presence of prevalent vertebral fractures. Multiple regression analysis adjusted for age, body height, weight, duration of diabetes, and serum creatinine showed that serum OC and OC/BAP ratio were correlated negatively with HbA1c (P?P?P?

2009-01-01

274

Proposal to negotiate an amendment to an existing contract for the supply of thick 6 inch silicon micro-strip sensors for the CMS tracker  

CERN Document Server

This document concerns the proposal to negotiate an amendment to an existing contract for the supply of thick 6 inch silicon micro-strip sensors for the CMS tracker. For the reasons explained in this document, the Finance Committee is invited to approve an amendment to an existing contract with HAMAMATSU PHOTONICS (CH) for the supply of 7 000 thick 6 inch silicon micro-strip sensors for the CMS tracker, for an amount of 3 248 000 euros (5 131 840 Swiss francs), not subject to revision, with an option for up to 11 000 additional sensors, for a maximum amount of 4 708 000 euros (7 438 640 Swiss francs), not subject to revision, bringing the total maximum amount of the amendment to 7 956 000 euros (12 570 480 Swiss francs) not subject to revision. This total maximum amount will be added to the initial contract amount of 415 835 000 Japanese yen (4 879 824 Swiss francs), not subject to revision. The amounts in Swiss francs have been calculated using the present rate of ...

2004-01-01

275

Post processing system for multi-dimensional thermal-hydraulic analyses  

International Nuclear Information System (INIS)

In the conventional visualization system for the computational results, only Japanese (Nihongo) Line Printer (NLP) was available to print two dimensional cross sectional plots of vector and scalar fields. To evaluate the phenomena, an analyst had to print many plots on the NLP. This task makes difficult to check the computational results immediately after the calculation. Recently, as the visualization tools, we introduced Micro AVS and Field View which are utilized widely in the scientific and the industrial fields. In order to show the numerical results on the visualization software, we constructed a post processing system which convert the results of the numerical code to 'intermediate files' which can be read by the visualization tools. As using this system, the examination of the numerical results can be executed on the display of the personal computer. Furthermore, the persuasive report and paper with high quality can be produced due to the color printing. As ...

1999-01-01

276

Overview of reliability test program on primary coolant piping of light water reactors  

Energy Technology Data Exchange (ETDEWEB)

Upon request by the Science and Technology Agency of Japanese Government, the Japan Atomic Energy Research Institute has conducted Piping Reliability Test Program to demonstrate the safety and reliability of light water reactor primary pipings. In this report, the results of the program are summarized. In the test program, pipe fatigue tests, Leak-Before-Break (LBB) verification tests and pipe rupture tests were carried out to examine the integrity of pipings, to verify the LBB concept and to demonstrate the effectiveness of the protective measures against jet impingement and pipe whip under pipe rupture event, respectively. In the pipe fatigue tests, a procedure to predict the fatigue crack growth was developed and the integrity of piping during plant service life was demonstrated. In the LBB verification tests, pipe fracture tests and leak rate tests were performed using cracked pipes. Based on the test results, LBB in the primary pipings was demonstrated. In the ...

1993-10-01

277

One-piece removal of JRR-3 reactor block  

Energy Technology Data Exchange (ETDEWEB)

JRR-3 is a research reactor of 10 MWt output, which attained the criticality in 1962. All the design, manufacture, installation and others of this reactor were carried out by Japanese technologies, except the fuel and heavy water as the moderator and coolant, therefore it is nicknamed Home-made No.1 Reactor. Recently, due to the change in the state of utilizing research reactors and the rise of quality in the utilization, JRR-3 has become to be unable to meet sufficiently the needs of users. The plan of reconstructing the JRR-3 was considered under such situation, and in order to reuse the reactor building, the reactor proper is removed, and an entirely new, high performance, versatile reactor is to be constructed. In this paper, as to the removal works of the JRR-3 reactor proper, the method of execution, design, the execution of works and so on are outlined. The removal works of the reactor facilities were started in February, 1986. The removal of the accessory ...

1987-07-01

278

Indoor thoron and radon concentration measurements with passive cup monitors  

International Nuclear Information System (INIS)

A new type of passive integrating cup monitors was developed to measure indoor thoron("2"2"0Rn) and radon("2"2"2Rn) concentrations. By placing a pair of cup monitors with different size a air exchange windows in the same place during a sufficient period of time the concentrations of both gases can be assessed from the alpha track densities on the CN films of the two monitors. The lower detection limit with a 3 months measurement period is for "2"2"0Rn 26.1 Bq*m"-"3 and is for "2"2"2Rn 6.1 Bq*m"-"3. Radon-220 and "2"2"2Rn concentrations have been measured in about 20 different types of dwellings around the Nagoya area with these monitors. The results suggest that the "2"2"0Rn concentrations were rather high in traditional Japanese dwellings made of a timber frame and mud. (orig.). (4 refs., 4 figs.).

1993-07-04

279

Increased transcription of the c-myc oncogene in two methylcholanthrene-induced quail fibroblastic cell lines  

Energy Technology Data Exchange (ETDEWEB)

The expression of three c-onc genes (c-erb, c-myc, c-myb) was investigated in five cell lines established from fibrosarcomas induced with 20-methylcholanthrene (MCA) of Japanese quails. These cell lines showed low levels of the three c-onc genes, with the exception of two cell lines that accumulated moderate (MCAQ 1-4) and large amounts (MCAQ 3-5) of c-myc RNA. Molecular cloning and restriction endonuclease analyses indicated that expression of c-myc in these two cell lines were not associated with detectable rearrangements in the c-myc locus, that the size of the c-myc transcript (2.7 kb) in MCAQ 3-5 was similar to that of the normal c-myc messenger RNAs (mRNA) and that the transcriptional activatin observed in MCAQ 3-5 was not mediated by the LTR (long terminal repeat) of a proximate ALV (avian leukosis virus) provirus. Finally, when analyzed with the restriction enzymes Msp I and Hpa II, the c-myc locus of MCAQ 3-5 and MCAQ 1-4 was found hypomethylated as ...

1984-12-01

280

Hepatic aflatoxin B1-DNA adducts and TP53 mutations in patients with hepatocellular carcinoma despite low exposure to aflatoxin B1 in southern Japan  

British Library Electronic Table of Contents (United Kingdom)

Abstract Background & aims: Hepatitis B or C virus infection is considered to be the main cause of hepatocellular carcinoma (HCC) in Japan. Aflatoxin B1 (AFB1) is a carcinogen associated with HCC in regions with high exposure. Mutations in codon 249, exon 7 are a hallmark of AFB1 exposure. Therefore, to clarify the role of AFB1 in hepatocarcinogenesis, we examined AFB1-DNA in liver tissue and sequenced TP53 in Japanese patients with HCC. Methods: Hepatocyte AFB1-DNA adducts were determined immunohistochemically and direct sequencing of TP53 was done to determine mutations in 188 of 279 patients who underwent hepatic resection for HCC. We assessed hepatitis C virus antibodies (HCV Ab) and HBSAg expression; patients without either were defined as having non-B non-C hepatocellular carcinoma (...

2011-01-01

281

Free-electron laser beam  

International Nuclear Information System (INIS)

The principle and history of free-electron laser (FEL), first evidenced in 1977, the relationship between FEL wavelength and output power, the high-power FEL driven by the superconducting linac, the X-ray FEL by the linac, and the medical use are described. FEL is the vacuum oscillator tube and essentially composed from the high-energy linac, undulator and light-resonator. It utilizes free electrons in the vacuum to generate the beam with wavelength ranging from microwave to gamma ray. The first high-power FEL developed in Japanese Atomic Energy Research Institute (JAERI) is based on the development of superconducting linac for oscillating the highest power beam. In the medical field, applications to excise brain tumors (in US) and to reconstruct experimentally blood vessels in the pig heart (in Gunma University) by lasing and laser coagulator are in progress with examinations to remove intra-vascular cholesterol mass by irradiation of 5.7#mu#m FEL beam. Cancer ...

2003-06-01

282

Flow induced vibration mock-up test for heat exchanger tubes of PWR steam generator  

International Nuclear Information System (INIS)

It is one of the most important subjects to estimate the flow-related stability of the heat exchanger tubes. A large scale model steam generator has been developed to verify the stability of the tubes in the Japanese PWR steam generators for the two-phase flow-induced vibration and to accumulate related technical data of thermal-hydraulic and flow-induced vibration of U-bend tube bundle. The model steam generator has 230 U-bend tubes of 46 different radius and 5 columns for each of practical diameter and material, and the anti vibration bars are inserted into each spacing between tube arrays. The freon R123 has been used as the secondary side fluid in stead of water-steam two-phase. In the test, void fraction and interfacial velocities in U-bend and straight tube-bundle are measured with bi-optical probes, and vibration responses of some selected tubes are measured with strain gauges and accelerators. It is verified that the U-bend tubes are stable when they are ...

2000-10-01

283

Evaluation of new corrosion-resistant superheater tubing in high-efficiency waste-to-energy plants  

Energy Technology Data Exchange (ETDEWEB)

Field corrosion tests were conducted on eight single tube materials and two welded overlay materials in three typical Japanese waste incineration plants in an effort to develop new corrosion-resistant superheater tubes capable of functioning efficiently under temperature and pressure conditions of 500 C and 100 kgf/cm{sup 2}-g in high-efficiency waste-to-energy (WTE) plants. Austenitic alloys containing higher concentrations of chromium, nickel, and molybdenum [Cr + Ni + Mo] showed excellent corrosion-resistant properties, and the new alloys JHN24 and HR30M showed good corrosion resistance. Different corrosion rates found in each of the three plants were explained by differences in operating conditions, such as gas temperature, concentration of molten salts resulting from chlorine (Cl) content of deposits, heavy metal (zinc oxide [ZnO] + lead oxide [PbO]) content, etc. It was confirmed that the corrosion rate of materials positioned in the first tube row facing the ...

1998-07-01

284

Effect of iron catalyst on the composition of oil from coal liquefaction  

Energy Technology Data Exchange (ETDEWEB)

The effect of two iron catalysts, red mud and CGS S-G, as well as Co-Mo/Al/sub 2/O/sub 3/ and Ni-Mo/Al/sub 2/O/sub 3/ commercial catalysts on the composition of oil derived from the liquefaction of Japanese subbituminous coal have been investigated comparatively by conventional autoclave experiments at 440 and 450C under initial hydrogen pressure of 85kg/cm/sup 2/ . G with tetralin to coal weight ratio of 3. From the results obtained at 450C, total conversion and the yield of gas revealed almost same level with four catalysts, but the oil product from molybdenum catalysts showed higher yield than that from iron catalysts. CGS S-G catalyst also showed higher yield of oil product than red mud catalyst. Reaction behavior of two iron catalysts were also tested by solvent recycle mode experiments.

1987-01-01

285

Dry coke quenching study. Final report, September 1978  

Science.gov (United States)

The financial evaluation of capital and operating cost estimates for a dry coke quenching facility installation indicates a marginal return on investment if the evaluation is based exclusively on steam credits. However, the potential improvements in environmental emissions and reported, but unverified, blast furnace operations may justify the expenditure. The Russian and Japanese claim of 2 to 4% reduction in blast furnace coke usage with up to 4% increase in iron production has not been demonstrated in the domestic steel industry and, therefore, is not included in the financial analysis. A 2% coke reduction represents a savings of approximately $0.81 per ton of hot metal produced or an additional annual credit of $1,800,000 for dry coke quenching, exclusive of productivity gains. Additional credit of this magnitude would increase the estimated discounted cash flow return from 10% to approximately 16% for the estimated capital expenditure of $21,742,652. The ...

1978-09-01

286

Crud removal performance with ion exchange resins in BWR plants  

Energy Technology Data Exchange (ETDEWEB)

It is needless to say that one of the most important roles of the condensate demineralizer in Japanese boiling water reactors (BWR) is to eliminate such impurities during accidental occurrence of sea water leakage from condensate cooling system. Ion exchange resins packed in condensate demineralizer have also been expected to decrease crud, or corrosion products (CP) in condensate water in order to finally reduce activated corrosion products (ACP) in the reactor coolant loop. It is perceived that crud removal ability of a condensate demineralizer has been improved year by year. And we call this phenomenon as `Aging Effect`. Typical property changes of aged cation exchange resin consisted of an increase of water retention capacity and a change of surface texture. Based on these findings, we formulated a new concept and developed new gel type ion exchange resins for the better crud removal. The results from column tests using actual condensate water for approximately ...

1996-01-01

287

Consolidation settlement analysis of pile foundations; Kui kiso no atsumitsu chinka kaiseki  

Energy Technology Data Exchange (ETDEWEB)

Deformation of the ground can be considered as a sum of volume deformation and shear deformation. At circumferential ground of pile axis, simple shear type of shear deformation becomes main factor of settlement. As shear forces with reverse direction are overlapped at parallel face for pile around face of the ground between the piles, the shear deformation is relaxed. At deeper place from top of the pile, volume deformation becomes larger and component of shear deformation approaches to a pure shear type. In case of the land surface loading type consolidation settlement calculation, a method adopting one dimensional consolidation calculating method using only vertical component within stress obtained by elasticity theory even when investigating multi dimensionally is used widely. In Japanese design standards, the method calculating the consolidation settlement by presuming imaginary loading face for land surface is widely adopted. In case of abrasion pile, the ...

1997-02-01

288

Change in pore structure of coals by activation with KOH; KOH fukatsushita sekitan no saiko kozo  

Energy Technology Data Exchange (ETDEWEB)

Three typical Japanese coals of non-coking coal, coking coal and anthracite were heat-treated with KOH, and change in their pore structure was examined by absorption of N2, X-ray diffraction and TEM observation. In addition, the relation between a coal rank and pore structure was also studied by absorption experiment of N2. In experiment, the mixture of coal and KOH in a nickel holder was heat-treated in N2 gas flow at heating rate of 2{degree}C/min, and held at a fixed temperature for one hour. To clarify the pore structure, N2 absorption isotherms were measured at -196{degree}C under nearly 76cmHg using a commercially available full-automatic absorption measurement equipment. Based on the X-ray diffraction and TEM observation results on activated coals, the relation between the N2 absorption and pore structure was studied. The results are summarized as follows: (1) The yield and absorption ability of coals increase with a coal rank, (2) The specific surface area ...

1996-10-28

289

Avian LH and FSH: comparison of several radioimmunoassays  

Energy Technology Data Exchange (ETDEWEB)

Comparisons were made between various LH and FSH radioimmunoassays currently being used to measure avian hormones. The two LH assays were the homologous chicken system of Follett et al. (1972) and the turkey assay of Burke et al. (1979). These assays were also used in heterologous arrangement by interchanging the iodinated LH fractions and antisera. Five FSH assays were analyzed: two homologous chicken systems (Scanes et al., 1977; Sakai and Ishii, 1980) an assay based on mammalian materials (rat FSH and anti-ovine FSH antiserum, and one using labelled turkey FSH (Burke et al., 1979) with an anti-chicken FSH antiserum. The potencies of purified chicken and turkey gonadotrophin preparations and of a range of plasma samples from Japanese quail were measured in each assay. The two LH systems showed some degree of species specificity, such that chicken LH was more active than turkey LH in the chicken assay, whereas the reverse was true in the turkey LH assay. The ...

1983-04-01

290

Applicability of chemical cleaning process to steam generator secondary side, (4). Comprehensive applicability evaluation of chemical cleaning and its effect on integrity of other structural materials other than steam generator tubes  

International Nuclear Information System (INIS)

The application of chemical cleaning for dissolving and removing scale and sludge is being planned in the Japanese pressurized water reactor (PWR) plant in order to maintain high heat transfer performance and to prevent steam generator (SG) tube degradation. In this paper, the effectiveness of the Electric Power Research Institute (EPRI) and German Kraftwerk Union (KWU) processes on the integrity of structural materials other than SG tubes and the comprehensive applicability of chemical cleaning are discussed. The integrity of structural materials such as carbon steel, low-alloy steel and stainless steel was maintained after the EPRI and KWU processes. KWU chemical cleaning tailored for crevice cleaning has been studied to improve its cleaning effectiveness in crevices and to control the corrosion depth of structural materials less than the criterion for corrosion depth. (author)

2006-11-01

291

X-ray phase imaging using a X-ray tube with a small focal spot. Improvement of image quality in mammography  

International Nuclear Information System (INIS)

Phase contrast X-ray imaging has been studied intensively using X-rays from synchrotron radiation and micro-focus X-ray tubes. However, these studies have revealed the difficulty of this technique's application to practical medical imaging. We have created a phase contrast imaging technique using a molybdenum X-ray tube with a small focal spot size for mammography. We identified the radiographic conditions in phase contrast magnification mammography with a screen-film system, where edge effect due to phase contrast overcomes geometrical unsharpness caused by the 0.1 mm-focal spot of a molybdenum X-ray tube. The edge enhancement due to phase imaging was observed in an image of a plastic tube, and then geometrical configuration of the X-ray tube, the object and the screen-film system was determined for phase imaging of mammography. In order to investigate a potential for medical application of this method, we conducted evaluation of the images of the American Collage of Radiology (ACR) ...

2002-03-01

292

Use of Teflon-embedded calcium sulphate: dysprosium thermoluminescent dosimeters for chest radiography  

Energy Technology Data Exchange (ETDEWEB)

As part of a U.S. multi-regional pilot study conducted by the six Centers for Radiological Physics, 12-mm-diameter by 0.4-mm-thick CaSO/sub 4/:Dy Teflon-embedded discs were evaluated and used to measure patient entrance exposure on 60 average patients at 12 clinical centers. The discs were found to have adequate sensitivity, reproducibility and linearity up to 69.7 microC kg-1 (270 mR). The minimum measurable exposure was estimated as 0.4 microC kg-1 (1.5 mR). All responses were corrected for energy dependence, which varied +/- 20% from 1.7 to 6.5 mm Al half-value layer. Patient entrance exposure values ranged from 1.3 to 28 microC kg-1 (5 to 110 mR), with a median value of 5.2 microC kg-1 (20 mR). This value agreed with exposure measurements made on the chest radiography equipment using an ionization chamber and a phantom which simulated an average patient, and with published Nationwide Evaluation of X-Ray Trends (NEXT) data for the same period.

1987-12-01

293

The validity of the density scaling method in primary electron transport for photon and electron beams  

International Nuclear Information System (INIS)

In the convolution/superposition method of photon beam dose calculations, inhomogeneities are usually handled by using some form of scaling involving the relative electron densities of the inhomogeneities. In this paper the accuracy of density scaling as applied to primary electrons generated in photon interactions is examined. Monte Carlo calculations are compared with density scaling calculations for air and cork slab inhomogeneities. For individual primary photon kernels as well as for photon interactions restricted to a thin layer, the results can differ significantly, by up to 50%, between the two calculations. However, for realistic photon beams where interactions occur throughout the whole irradiated volume, the discrepancies are much less severe. The discrepancies for the kernel calculation are attributed to the scattering characteristics of the electrons and the consequent oversimplified modeling used in the density scaling method. A technique called the kernel integration ...

294

The treatment of chronic pain by epidural spinal cord stimulation--a 15 year follow up; present status.  

Science.gov (United States)

Pain is necessary for survival but chronic pain is disabling and causes significant health and economic problems. This study provides an understanding of the future for spinal cord stimulation. Stimulation by means of chronically implanted electrodes, was carried out in 200 patients with pain of varied benign organic etiology. In 177 of them, pain was confined to the failed back syndrome. Most patients were referred by a Pain Management Service. 226 epidural implants were used: 80 unipolar, 59 Resume, 12 bipolar, and 75 quadripolar. Patients were followed for periods of 6 months to 12 years, with a mean follow-up of 44 months. 84 patients (42%) were able to control their pain by stimulation alone, 22 patients (11%) needed occasional analgesic supplements along with their stimulation program. Pain secondary to failed back syndrome, multiple sclerosis, peripheral vascular disease, sympathetic dystrophy and diabetic neuropathy responded favorably. Pain due to cauda equina injury, ...

1997-06-01

295

Simultaneous assessment of left ventricular function from gated myocardial perfusion SPECT. Utility of QGS (Quantitative Gated SPECT) program  

International Nuclear Information System (INIS)

Quantitative gated SPECT (QGS) was evaluated in 7 normal volunteers and 31 patients with cardiac diseases. Adequate cut off value of a prefilter was 0.45. In phantom, the left ventricular volume value was 93.9% of determined value by 180-degree projection in L type and 98.8% by 360-degree projection in opposed type. In normal volunteers, LVEF measured by QGS program related to value by first pass method. As for functional map, regional EF and wall motion decreased at the septum side, and wall thickening at base side of heart. Good correlation was recognized (p<0.0001) between blood flow image and functional map (regional EF and wall thickening). In 20 cases of acute myocardial infarction, lesion was detected conspicuously in regional EF and wall motion. The accuracy of coronary arterial stenosis improved in functional map (regional EF 92%, wall motion 92% and wall thickening 88%). In particular, the accuracy of 3 rami lesion was 100% in functional map and higher ...

1998-08-01

296

Scatter measurements for optical cone-beam computed tomography  

Energy Technology Data Exchange (ETDEWEB)

Both x-ray and optical cone-beam CT (CBCT) scanners are limited by scattered photons that contaminate the primary images. Transparent radiochromic gels and plastics are anticipated to produce less scattering than polymerization gels and hence result in reconstructed dose distributions with greater contrast and dynamic range. Four methods of scatter measurement were investigated to quantify scatter fractions using an in-house optical CBCT scanner. The methods consisted of generating either 'coin' shadows or primary beamlets in transmission images. The four methods generated similar results of 10% scatter fractions in gel transmission images for this particular scanner configuration with both leuco crystal violet and carbon black micelle gels. The scatter contributions were distributed as 5% from micelle gel, 2% from Teflon wall, 2% from refractive index matching liquid and 1% other sources. Applying a uniform background subtraction of 2% of open field intensity ...

2009-05-01

297

Pharmacokinetic and dosimetric characteristics of some thallium isotopes  

International Nuclear Information System (INIS)

Pharmacokinetics is studied, radiation doses to patients when using domestic thallium-201 chloride in diagnosis of the heart ischemic disease is estimated; contribution into the total dose of thallium-201 (1.5 %), thallium-201 (0.2 %) and lead-201 + lead-203 (0.05 %) radionuclide impurities is also determined. Internal doses were estimated for a heterogeneous phantom of a standard man; the calculations were carried out using a computer. Scanning of patients which were treated with radiopharmaceuticals to be diagnosed was carried out using a whole body counter and gamma-chamber. Large intestine, kidneys and thyroid are the critical organs when using thallium-201 chloride. The highest contribution into the dose to organs and the whole body from thallium-200 and thallium-202 impurities being contained in thallium-201, doesn't exceed 8.6 %. The contribution into the dose from lead-201 and lead-203 may be ignored. Doses from thallium-199 preparation per activity unit ...

298

Performance testing of selected types of electronic personal dosimeters used in Sudan  

International Nuclear Information System (INIS)

Measurements were carried out for calibration and performance testing of a set of 10 electronic personal dosimeters (EPDs) at the Secondary Standard Dosimetry Laboratory of Sudan. Calibrations were carried out at three X-ray beam qualities described in ISO standard 4037 in addition to 137Cs and 60Co gamma ray beams. The experimental was performed with EPDs mounted on ICRU Slab phantom. X-ray and ?-ray beams were characterized in terms of air kerma free-in-air which were converted to the known delivered personal dose equivalent, Hp(10) using appropriate the air kerma to personal dose equivalent conversion coefficients. Dosimeters tested showed excellent energy and angular response and relative error of indication within the recommended limit for photon energies from 65 keV to 1.25 MeV. The study showed encouraging results for using electronic dosimeters in personal dosimetry.

2010-12-01

299

Measurement of spatial dose distribution with thermoluminescence sheet around high dose-rate intracavitary sup 60 Co sources  

Energy Technology Data Exchange (ETDEWEB)

A thermoluminescence (TL) sheet and its spatial readout system for in vivo measurement of spatial dose distribution around sources has been newly developed for intracavitary high dose-rate radiation therapy. The TL sheet (40 cm x 50 cm x 200 {mu}m), which is composed of teflon mixed with BaSO{sub 4} (Eu doped) powder, has a linear response with a very wide dynamic range from at least 0.002 cGy to 5000 cGy for {sup 60}Co sources. Phantom test of the TL sheet readout system demonstrated that absorbed dose with TL sheet and that with ionization chamber as standard dosimeter agreed well. For clinical application, TL sheet was attached on an applicator of intracavitary radiation therapy for rectal cancer. After irradiation with high dose-rate {sup 60}Co sources, the in vivo dose distribution on the surface of the rectum was determined. The TL sheet was suggested to provide a convenient means of measuring the dose distribution around {sup 60}Co sources in intracavitary ...

1991-06-01

300

Is energy imparted a good measure of the radiation risk associated with CT examinations  

International Nuclear Information System (INIS)

The dose distribution in a Rando phantom has been measured for typical EMI 5005 CT scans of the head, chest, abdomen and pelvis. These dose distributions have been used to generate quantitative estimates of the somatic and genetic radiation risks associated with these CT examinations and also to measure the total energy imparted during each scan. A comparison has been made between the radiation risk estimates and the energy imparted measurements. The energy imparted measurements are not a good indicator of the somatic and/or genetic risks when one type of CT scan is compared with another. However, for a given type of scan, the energy imparted may be a reasonable indicator of the relative somatic risks associated with different CT examinations. Considerable care should be taken when interpreting and using any measured value of energy imparted in a radiological examination since published values of the risk per unit energy imparted can significantly underestimate the ...

301

Fluorescence based molecular in vivo imaging; Fluoreszenzgestuetzte molekulare Bildgebung in vivo  

Energy Technology Data Exchange (ETDEWEB)

Molecular imaging represents a modern research area that allows the in vivo study of molecular biological process kinetics using appropriate probes and visualization methods. This methodology may be defined- apart from the contrast media injection - as non-abrasive. In order to reach an in vivo molecular process imaging as accurate as possible the effects of the used probes on the biological should not be too large. The contrast media as important part of the molecular imaging can significantly contribute to the understanding of molecular processes and to the development of tailored diagnostics and therapy. Since more than 15 years PTB is developing optic imaging systems that may be used for fluorescence based visualization of tissue phantoms, small animal models and the localization of tumors and their predecessors, and for the early recognition of inflammatory processes in clinical trials. Cellular changes occur during many diseases, thus the molecular imaging ...

2008-12-15

302

Experimental determination of the dosimetric characteristics for the I-Plant"T"M model 3600 "1"2"5I brachytherapy source  

International Nuclear Information System (INIS)

The dosimetric characteristics for a new brachytherapy seed source (I-Plant"T"M model 3600) were measured using LiF thermoluminescent dosimeters and appropriate phantom materials in conformance with the methodology and guidance provided by the AAPM Task Group 43. The I-Plant"T"M model 3600 is the successor to the I-Plant"T"M model 3500. The major difference between these sources is that the model 3600 contains a leaded-glass core to provide radio-opacity (while the model 3500 contains a silver core), which does not produce spectral contamination upon neutron activation. The dose rate constant #LAMBDA# for the model 3600 was determined to be 1.00 Gy h"-"1 U"-"1 (with a 6% overall relative standard deviation), compared to 1.01 cGy h"-"1 U"-"1 reported for the model 3500 in previous studies. The remaining dosimetric characteristics also are similar for both sources.

2005-06-01

303

Evaluation of the increase of superficial dose due to thermoplastic immobilizing in radiotherapy; Avaliacao dos efeitos de superficializacao de dose por imobilizadores termoplasticos em radioterapia  

Energy Technology Data Exchange (ETDEWEB)

Perforated thermoplastic masks are used to provide patients immobilization. This procedure inserts a material in the path of the radiation beam, that attenuates and modifies the beam fluence and flatness. The present study evaluates the increase in skin dose as a result of using thermoplastic masks. Relative doses were measured on the surface of a solid water phantom, in the presence and absence of masks. These masks were stretched according to deformation patterns observed in clinical routine. The measurements were obtained with a plane-parallel chamber (Markus type 23343) and radiochromic film (EBT Gafchromic) for 6MV X-rays from a linear accelerator, and for a radiation beam from a cobalt therapy unit. The results showed that thermoplastic masks, whose thickness varied between 2 and 3 mm, increased the dose on the surface by a factor of 3. Due to the variations in the skin dose distribution, clinical procedures were suggested to minimize radiobiological damages ...

2010-07-01

304

Evaluation of the increase of superficial dose due to thermoplastic immobilizing in radiotherapy  

International Nuclear Information System (INIS)

Perforated thermoplastic masks are used to provide patients immobilization. This procedure inserts a material in the path of the radiation beam, that attenuates and modifies the beam fluence and flatness. The present study evaluates the increase in skin dose as a result of using thermoplastic masks. Relative doses were measured on the surface of a solid water phantom, in the presence and absence of masks. These masks were stretched according to deformation patterns observed in clinical routine. The measurements were obtained with a plane-parallel chamber (Markus type 23343) and radiochromic film (EBT Gafchromic) for 6MV X-rays from a linear accelerator, and for a radiation beam from a cobalt therapy unit. The results showed that thermoplastic masks, whose thickness varied between 2 and 3 mm, increased the dose on the surface by a factor of 3. Due to the variations in the skin dose distribution, clinical procedures were suggested to minimize radiobiological damages ...

2010-08-18

305

Dosimetric characteristics of backscattered electrons in lead  

Energy Technology Data Exchange (ETDEWEB)

In electron beam therapy, tissue overdose due to electrons backscattered from lead has been profusely studied. To quantify this dose enhancement effect, an electron backscatter factor (EBF) wasdefined as the ratio of dose at the tissue-inhomogeneity interface with and without the scatterer present. The dependence of the EBF on energy at the scatterer surface is not well known for energies lower than 3 MeV which is the most frequent clinical situation. In this work, we have done Monte Carlo calculations with the GEANT code to study EBF in lead at this energy range. The applicability of this code and the developed procedure for dose estimation has been experimentally verified. The dependence of the EBF on the beam energy incident on the scatterer has been studied for different nominal beam energies incident at the phantom's surface. The results show a trend of increase of EBF with the beam energy incident on the scatterer between 0.5 and 1.5 MeV, keeping ...

2000-07-01

306

Diagnostic capability of digital radiography of the chest using scanning laser stimulated luminescence  

Energy Technology Data Exchange (ETDEWEB)

Diagnostic capability of Fuji Computed Radiography (FCR) of the chest was compared to the conventional radiography (CoR) using regular film-screen system. FCR utilizers imaging plates of scanning laser stimulated luminescence. Visibility of 14 structures of the chest radiography was evaluated by 3 radiologists in 100 pairs of FCR and CoR which were taken at the same time with the same exposure factors. FCR was superior to CoR especially in observation of the mediastinum and areas behind the heart and diaphragm. The minor fissure was better seen on CoR. Superiority of FCR to CoR was thought to be mainly due to the processed image of FCR, and the so-called normal image of FCR had little diagnostic advantage. Simulated abnormal densities: nodular, alveolar, and interstitial densities with a chest phantom, were made, and detectability of alteration of these densities on FCR and CoR was evaluated by 19 radiologists, using ROC curve analysis. FCR and CoR revealed the ...

1989-02-01

307

Diagnostic capability of digital radiography of the chest using scanning laser stimulated luminescence  

International Nuclear Information System (INIS)

Diagnostic capability of Fuji Computed Radiography (FCR) of the chest was compared to the conventional radiography (CoR) using regular film-screen system. FCR utilizers imaging plates of scanning laser stimulated luminescence. Visibility of 14 structures of the chest radiography was evaluated by 3 radiologists in 100 pairs of FCR and CoR which were taken at the same time with the same exposure factors. FCR was superior to CoR especially in observation of the mediastinum and areas behind the heart and diaphragm. The minor fissure was better seen on CoR. Superiority of FCR to CoR was thought to be mainly due to the processed image of FCR, and the so-called normal image of FCR had little diagnostic advantage. Simulated abnormal densities: nodular, alveolar, and interstitial densities with a chest phantom, were made, and detectability of alteration of these densities on FCR and CoR was evaluated by 19 radiologists, using ROC curve analysis. FCR and CoR revealed the ...

1989-01-01

308

Development of a dual-detector X-ray imaging system for phase retrieval study  

International Nuclear Information System (INIS)

Based on a recently introduced phase X-ray imaging approach, a dual-detector prototype was developed for in-line X-ray phase imaging and phase retrieval utilizing a micro-focus X-ray source and two computed radiography (CR) cassette detectors. The system was built on a horizontal optical rail to facilitate manual adjustment of the positions of the X-ray source, the sample and the detectors. The novel design of the detector-1 is essential, it detects a portion of radiation to form an attenuation image; allows the rest of radiation to reach the detector-2 to form a phase contrast image, and the two images are used to retrieve a phase map. The two detectors are balanced for optimal phase-retrieval with reasonable radiation dose to the object to be imaged. The system was examined in terms of the linearity, the fractions of the X-ray photons detected by the two detectors, respectively and the imaging quality of phantoms. Preliminary results showed that the system is ...

2007-01-01

309

Computed radiography  

International Nuclear Information System (INIS)

In an effort to evaluate the feasibility of introducing computed radiography (FCR) into mass screening for lung cancer, the ability of FCR to detect nodules one cm in diameter was examined using a humanoid chest phantom. Based on the receiver operating characteristic (ROC) analysis, the detectability of FCR was compared with that of conventional radiography and photofluorography. The values of area under ROC curves were higher for FCR (0.963 for image similar to that with conventional film-intensifying screen system, image A; and 0.952 for processed image, image B) than the other two methods (0.774 for radiography and 0.789 for photofluorography). Degradation of image quality in FCR could be avoided by a wide latitude even if proper exposure techniques might not be employed. Images A and B in FCR yielded excellent delineation for nodules in the lung field and in the retrocardiac and subdiaphragmatic regions, respectively. This may have implications for the value of ...

1987-01-01

310

Chromosome aberrations in human lymphocytes from the plateau region of the Bragg curve for a carbon-ion beam  

Energy Technology Data Exchange (ETDEWEB)

Radiotherapy with high-energy carbon ion beams can be more advantageous compared to photons because of better physical dose distribution and higher biological efficiency in tumour cell sterilization. Despite enhanced normal tissue sparing, damage incurred by normal cells at the beam entrance is unavoidable and may affect the progeny of surviving cells in the form of inheritable cytogenetic alterations. Furthermore, the quality of the beam along the Bragg curve is modified by nuclear fragmentation of projectile and target nuclei in the body. We present an experimental approach based on the use of a polymethylmethacrylate (PMMA) phantom that allows the simultaneous exposure to a particle beam of several biological samples positioned at various depths along the beam path. The device was used to measure the biological effectiveness of a 60 MeV/amu carbon-ion beam at inducing chromosomal aberrations in G{sub 0}-human peripheral blood lymphocytes. Chromosome spreads were ...

2007-06-15

311

BDTPS The BNCT Treatment Planning System jointly developed at DIMNP and JRC/IE  

CERN Document Server

The idea to couple the Treatment Planning System (TPS) to the information on the real boron distribution in the patient is the main added value of the new methodology set-up at DIMNP of University of Pisa, in collaboration with the JRC of Petten (NL). The methodology has been implemented in the new TPS, called BDTPS (Boron Distribution Treatment Planning System), which takes into account the actual boron distribution in the patient brain, while the standard TPS assumes a uniform boron distribution, absolutely far from the reality. Nowadays, Positron Emission Tomography (PET) is able to provide this in vivo information. The new TPS, based on the Monte Carlo technique, has been validated comparing the main BNCT parameters (thermal flux, boron dose, etc.) as measured during the irradiation of a special heterogeneous boron phantom (HEBOM), ad hoc designed, as calculated by the BDTPS and by the standard TPS SERA. An evident SERA overestimation of the thermal neutron ...

2003-01-01

312

Assessment of the effects of pixel loss on image quality in direct digital radiography  

Energy Technology Data Exchange (ETDEWEB)

Modern digital radiographic 'flat panel' detectors can exhibit a progressive form of image degradation arising from non-functioning pixels. The effect of these 'dead pixels' on the quantitative image quality measures of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE) is investigated by a simulated degradation of images obtained from an Hologic EPEX system. The effects on the semi-quantitive measures obtained from contrast threshold test objects and resolution gratings are also investigated. Results suggest that the contrast-detail tests often employed in quality assurance measures are not sufficient to reveal the presence of dead pixels until well beyond the recommended replacement point for the flat panel detector. However, measurements of spatial resolution using a line pairs phantom were found to be more sensitive to pixel loss. Measurement of the MTF, NPS and DQE can ...

2004-03-21

313

Assessment of the effects of pixel loss on image quality in direct digital radiography  

International Nuclear Information System (INIS)

Modern digital radiographic 'flat panel' detectors can exhibit a progressive form of image degradation arising from non-functioning pixels. The effect of these 'dead pixels' on the quantitative image quality measures of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE) is investigated by a simulated degradation of images obtained from an Hologic EPEX system. The effects on the semi-quantitive measures obtained from contrast threshold test objects and resolution gratings are also investigated. Results suggest that the contrast-detail tests often employed in quality assurance measures are not sufficient to reveal the presence of dead pixels until well beyond the recommended replacement point for the flat panel detector. However, measurements of spatial resolution using a line pairs phantom were found to be more sensitive to pixel loss. Measurement of the MTF, NPS and DQE can reveal small changes in image quality ...

2004-03-21

314

A comparison study for dose calculation in radiation therapy: pencil beam Kernel based vs. Monte Carlo simulation vs. measurements  

International Nuclear Information System (INIS)

Accurate dose calculation in radiation treatment planning is most important for successful treatment. Since human body is composed of various materials and not an ideal shape, it is not easy to calculate the accurate effective dose in the patients. Many methods have been proposed to solve inhomogeneity and surface contour problems. Monte Carlo simulations are regarded as the most accurate method, but it is not appropriate for routine planning because it takes so much time. Pencil beam kernel based convolution/superposition methods were also proposed to correct those effects. Nowadays, many commercial treatment planning systems have adopted this algorithm as a dose calculation engine. The purpose of this study is to verify the accuracy of the dose calculated from pencil beam kernel based treatment planning system comparing to Monte Carlo simulations and measurements especially in inhomogeneous region. Home-made inhomogeneous phantom, Helax-TMS ver. 6.0 and Monte ...

2002-10-20

315

Study on dose distribution of therapeutic proton beams with prompt gamma measurement  

Energy Technology Data Exchange (ETDEWEB)

The proton beam has an advantage of the sharp dose falloff in dose distribution called Bragg peak while conventional radiation therapy modalities such as photons exhibit considerable amount of exit dose. To take advantage of this property it is important to know the exact location of the distal dose falloff. An error can cause overdose to the normal tissue or underdose to the tumor volume. The only way of finding out the dose distribution in-situ in particle therapy is to measure the gammas produced by nuclear reactions with tissue materials. Two kinds of gammas can be used: one is prompt gamma and the other is coincident gamma from the positron-emission isotopes. We chose to detect prompt gammas, and developed a prompt gamma scanning system (PGS). The proton beams of the proton therapy facility at National Cancer Center were used. The gamma distribution was compared to the dose distribution measured by an ionization chamber at three different energies of 100, 150, 200 MeV's. ...

2007-03-15

316

Accuracy of patient dose calculation for lung IMRT: A comparison of Monte Carlo, convolution/superposition, and pencil beam computations  

International Nuclear Information System (INIS)

The accuracy of dose computation within the lungs depends strongly on the performance of the calculation algorithm in regions of electronic disequilibrium that arise near tissue inhomogeneities with large density variations. There is a lack of data evaluating the performance of highly developed analytical dose calculation algorithms compared to Monte Carlo computations in a clinical setting. We compared full Monte Carlo calculations (performed by our Monte Carlo dose engine MCDE) with two different commercial convolution/superposition (CS) implementations (Pinnacle-CS and Helax-TMS's collapsed cone model Helax-CC) and one pencil beam algorithm (Helax-TMS's pencil beam model Helax-PB) for 10 intensity modulated radiation therapy (IMRT) lung cancer patients. Treatment plans were created for two photon beam qualities (6 and 18 MV). For each dose calculation algorithm, patient, and beam quality, the following set of clinically relevant dose-volume values was reported: (i) minimal, median, ...

2006-09-01

317

MRI evaluation and image processing in gel dosimetry. A study of selected MRI properties and image processing in 3D gel dosimetry  

Energy Technology Data Exchange (ETDEWEB)

Gel dosimetry is a new dosimetry method applied in radiation therapy. Gel dosimeters consist of a radiation sensitive gel, which can integrate absorbed doses from several radiation sources or beams. The dose to the gel can be evaluated by magnetic resonance imaging (MRI), a procedure that is the focus of the present thesis. A robust tool for the evaluation of the nonuniformity in MRI has been developed, the Deviation Image method. Unlike previously presented methods, the Deviation Image method includes all nonuniformity variations across a phantom surface and is insensitive to stochastic noise. Methods for the estimation of stochastic noise were analyzed in terms of sensitivity to nonuniformities. A method that averages the stochastic noise level over five regions over the phantom surface, and a method that assesses the stochastic noise level from the background, were found to be the methods of choice. Pronounced MR image nonuniformity ...

2001-03-01

318

Implementation of an algorithm for absorbed dose calculation in high energy photon beams at off axis points  

International Nuclear Information System (INIS)

Full text: A semiempirical algorithm for absorbed dose calculation at off-axis points in irregular beams was implemented. It is well known that semiempirical methods are very useful because of their easy implementation and its helpfulness in dose calculation in the clinic. These methods can be used as independent tools for dosimetric calculation in many applications of quality assurance. However, the applicability of such methods has some limitations, even in homogeneous media, specially at off axis points, near beam fringes or outside the beam. Only methods derived from tissue-air-ratio (TAR) or scatter-maximum-ratio (SMR) have been devised for those situations, many years ago. Despite there have been improvements for these manual methods, like the Sc-Sp ones, no attempt has been made to extend their usage at off axis points. In this work, a semiempirical formalism was introduced, based on the works of Venselaar et al. (1999) and Sanz et al. (2004), aimed to the Sc-Sp separation. This ...

2008-10-19

319

Updated estimates of the proportion of childhood leukaemia incidence in Great Britain that may be caused by natural background ionising radiation  

Energy Technology Data Exchange (ETDEWEB)

The aetiology of childhood leukaemia remains generally unknown, although exposure to moderate and high levels of ionising radiation, such as was experienced during the atomic bombings of Japan or from radiotherapy, is an established cause. Risk models based primarily upon studies of the Japanese A-bomb survivors imply that low-level exposure to ionising radiation, including to ubiquitous natural background radiation, also raises the risk of childhood leukaemia. In a recent paper (Wakeford et al 2009 Leukaemia 23 770-6) we estimated the proportion of childhood leukaemia incidence in Great Britain attributable to natural background radiation to be about 20%. In this paper we employ the two sets of published leukaemia risk models used previously, but use recently published revised estimates of natural background radiation doses received by the red bone marrow of British children to update the previous results. Using the newer dosimetry we calculate that the best ...

2009-12-01

320

Three novel mutations responsible for Cockayne syndrome group A  

International Nuclear Information System (INIS)

Cockayne syndrome (CS) is a rare autosomal recessive disease, which shows diverse clinical symptoms such as photosensitivity, severe mental retardation and developmental defects. CS cells are hypersensitive to killing by ultraviolet (UV)-irradiation and defective in transcription-coupled repair. Two genetic complementation groups in CS (CS-A and CS-B) have been identified. We analyzed mutations of the CSA gene in 5 CS-A patients and identified 3 types of mutations. Four unrelated CS-A patients (CS2OS, CS2AW, Nps2 and CS2SE) had a deletion including exon 4, suggesting that there is a founder effect on the CSA mutation in Japanese CS-A patients. Patient CS2SE was a compound heterozygote for this deletion and an amino acid substitution at the 106th glutamine to proline (Q106P) in the WD-40 repeat motif of the CSA protein, which resulted in a defective nucleotide excision repair. Patient Mps1 had a large deletion in the upstream region including exon 1 of the CSA gene. ...

2003-02-01

321

Strategy and management of network security at KEK  

International Nuclear Information System (INIS)

Recently the troubles related to the network security have often occurred at KEK. According to their security policy, the authors have started the strategy against the daily attacks. It consists of two fundamental things; the monitoring and the access control. To monitor the network, the authors have installed the intrusion detection system and have managed it since 1998. For the second thing, the authors arranged three categories to classify all hosts (about 5000 hosts) at KEK according to their security level. To realize these three categories, the authors filter the incoming packet from outside KEK whether it has a SYN flag or not. The network monitoring and the access control produced good effects in keeping the security level high. Since 2000 the authors have started the transition of LAN from shared-media network to switched network. Now almost part of LAN was re-configured and in this new LAN 10 Mbps 100 Mbps/1Gbps Ethernet are supported. Currently the authors are planning ...

2001-09-03

322

Recent progress of the JAERI free electron laser driven by a compact superconducting RF linac  

International Nuclear Information System (INIS)

A prototype for a quasi-cw, and high-average power free electron laser (FEL) driven by a 15 MeV superconducting rf linac has been developed, and constructed at Tokai, JAERI since 1989. Cryogenic and accelerating fields' performances of four JAERI superconducting accelerator modules have been realized without any serious problem in the FEL accelerator vault and experimental hall. Since modification and related maintenance of the cryogenic refrigerator system for the driver were completed in the middle of October 1995, the system has run with no trouble, and the driver has been continuously run very successfully up to now. The optical resonator system and related electron beam transport system have been modified to realize larger acceptance than the old for both of the undulator radiation and energetic electron beam in 1995 Japanese fiscal year. In the modification, an alignment and distance measurement system has been newly developed, and successfully applied to ...

1997-02-28

323

Present status of study on reduced-moderation water reactors  

Energy Technology Data Exchange (ETDEWEB)

The Reduced-Moderation Water Reactor (RMWR) is a next generation water-cooled reactor, based on the experienced light water reactor (LWR) technology, aiming at effective utilization of uranium resources, high burn-up and long operation cycle and plutonium multiple recycling. These characteristics can be achieved by the high conversion ratio from {sup 238}U to {sup 239}Pu resulted from the higher neutron energy spectrum in comparison to conventional LWRs. Considering the extension of LWR utilization, Japan Atomic Energy Research Institute (JAERI) started the research on it in 1997 and then started a collaboration in the conceptual design study with the Japan Atomic Power Company (JAPC) in 1998, under technical cooperation with three Japanese reactor vendors. In the core design study of the RMWR, several basic core designs with the high conversion ratio more than 1 and the negative void reactivity coefficient have been proposed, and then, subsequent investigation on ...

2001-09-01

324

Overview of steam generator stress corrosion experience in U.S. PWR'S  

International Nuclear Information System (INIS)

The detection, in European steam generators, of intergranular stress corrosion cracking initiating from the primary side (PWSCC) and the somewhat similar detection of intergranular stress corrosion (IGSCC) and intergranular corrosion (IGA) initiated from the secondary side in Japanese steam generators has led to a growing awareness of the potential for such corrosion forms in United States PWR steam generators. What had been a minor occurrence at several units is now a cause of concern and repair measures at more than 30 sites in the United States, and in some cases, is the major cause of steam generator unavailability. The United States nuclear utilities and EPRI formed the first Steam Generator Owners' Group (SGOG) in 1977 in response to the prospect of continued denting corrosion. The occasional appearance of PWSCC, IGSCC and IGA in domestic steam generators was not a sufficient cause for initiating an extensive research program in SGOG I. In SGOG II ...

325

Method for predicting diffusion of discharged warm water in the regions of coastal sea  

International Nuclear Information System (INIS)

The present situation of the researches that have been made for predicting the process and range of diffusion of warm drain is reviewed. This review is divided into eight sections. The first section deals with the present situation of warm drain from power plants. For the establishment of drainage standard, there are many difficult problems to be solved because water temperature differs in its nature from other regulation items. In the second section, the process of diffusion and cooling of warm drain is explained. The third section deals with the diffusion characteristics of warm drain in Japanese coastal sea due to water temperature. Two types of diffusion are known. One is dominant irregular current, and the other is periodical reciprocating stream. The fourth section deals with the methods of prediction of diffusion. Research methods and simulation models are described. The fifth section deals with the prediction with single layer model. Fundamental ...

1975-01-01

326

Long-term durability of dentin bonds made with a self-etching primer, in vivo.  

Science.gov (United States)

The long-term durability of bonds between adhesive resins and dentin is of significant importance for the longevity of bonded restorations. We carried out an in vivo one-year study to evaluate the durability of resin-dentin bonds in the oral cavity, as well as to test the hypothesis that the adhesive interface would show morphological changes in vivo over time. Very shallow saucer-shaped dentin cavities were prepared in 12 intact teeth of one Japanese monkey (Macaca fuscata) under general anesthesia. The cavities were restored with Clearfil Liner Bond II and Clearfil Photo Posterior resin composite. The teeth were extracted at three different times: immediately, and 180 and 360 days after placement of the restorations. One day after the monkey was killed, specimens of the three time periods were subjected to the micro-tensile bond test at a crosshead speed of 1 mm/min. The surfaces of the failed bonds were observed under a field emission scanning electron ...

1999-04-01

327

LS&T and CMS FY 2004 Feasibility Proposal 04-FS-006 - Ceramic Laser Materials Interim Report - June 8, 2004  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this memo is to give an update on our work on ceramic laser materials--feasibility proposal 04-FS-006. Transparent ceramic materials have several major advantages over single crystals in laser applications including, ease and robustness of manufacturing, large apertures, design flexibility, fracture toughness, high activator concentrations, uniformity of composition, no residual stress, and others discussed in the proposal. After a decade of working on making transparent YAG:Nd in 1995 Japanese workers demonstrated samples for the first time that performed as well in lasers as their single crystal counterparts. Since then several laser materials have been made and evaluated. For these reasons, developing ceramic laser materials is the most exciting and futuristic materials topic in today's major solid-state laser conferences. The highlights and executive summary of our work to date are: (1) Ordered a slab of transparent YAG:Nd from Konoshima ...

2005-02-03

328

International ESCO business opportunities and challenges: a Japanese case study  

Energy Technology Data Exchange (ETDEWEB)

Recently, US energy service companies (ESCOs) have begun to actively explore markets outside the US. Despite the needs of many countries for ESCO involvement, ESCOs face many challenges (i.e., marketing, financial, institutional, political and cultural barriers). Consequently, most of these firms pursue international project opportunities very selectively due to the costs and risks associated with project development. Despite these barriers, some ESCOs view international work as a strategic expansion of their business, assuming that there will be adequate business in the future to repay them for their initial investment. In this paper, the authors present the findings from a recently completed study on the proposed development of an ESCO industry in Japan. The study was based on four sources of information: (1) a review of the published and unpublished literature on ESCOs; (2) interviews with 26 ESCOs in the US, the US Department of Energy, and the National Association of Energy ...

1997-10-01

329

Initiation process of type 1 pitting corrosion on copper water-tubes; Reisui yo dokan ni okeru 1 gata koshoku no hassei  

Energy Technology Data Exchange (ETDEWEB)

Copper tubes have been widely used for water supply and heat exchangers. In such systems copper tubes often suffer from type 1 pitting-corrosion. A mechanism, of the type I pitting-corrosion on copper tubing has been presented, but a initiation mechanism of the pitting corrosion is still unknown. In this paper we aimed to clarify the initiation mechanism of the pitting corrosion. Copper-tube specimens were immersed in a circulating solution. The solution had been used for heat exchangers at a Japanese factory where the water leakage occurred by the pitting corrosion on copper tubes. The solution contained tiny precipitates resulted from corrosion of galvanized steel pipe. During the immersion test changes in the surface state of a copper tube was analyzed by in situ RAMAN (in situ Raman Spectroscopy), SEM (Scanning Electron Microscope), EPMA (Electron Probe Microanalysis), AES (Auger Electron Spectroscopy) and XPS (X-ray Photoelectron Spectroscopy). The pitting ...

1999-07-15

330

Human exposure to PCDDs, PCDFs, and dioxin like PCBs in Japan, 2001  

Energy Technology Data Exchange (ETDEWEB)

In our previous study, we have estimated the level of human exposure to dioxins (PCDDs, PCDFs, and Dioxin like PCBs) in Japan based on dioxins monitoring data and results of total diet studies (TDS) in fiscal 2000 (April 2000- March 2001). It has been reported that the national PCDDs/DFs emission in 2001 against the 1997 level has been reduced by approximately 77% In addition, reduction of environmental levels was reported. The enforcement of Japan's Law Concerning Special Measures against Dioxins has significant impact on the reduction of the average dioxins concentrations in the ambient air. Therefore, the transitions of Japanese dioxins exposure levels in recent years are worthy of attention. In order to determine exposure level in fiscal 2001, collection and compilation for surveillance results derived from the regular environmental monitoring under the law as well as other dioxins surveys by national and local governmental bodies were continued, and ...

2004-09-15

331

Evaluation of the performance of a dual fuel engine  

Energy Technology Data Exchange (ETDEWEB)

Dual fuel operation, in which natural gas is mixed with the diesel engine intake air and ignition is by diesel fuel spray, has the advantage that engine conversion is simple. Under high load it has the same high efficiency as a diesel engine and it can be switched to normal diesel operation for long distance running. Also, NO{sub x} and black smoke emissions can also be reduced. However, the disadvantages are to increase HC and CO emissions, to reduce efficiency under low load, and to emit the large amount of NO{sub x} under high load. Waseda University was commissioned by Tokyo Gas Co., Ltd. to conduct research program involving experimentation ragarding a dual fuel engine. It was then discovered that the most effective means of solving the problems mentioned above is Exhaust Gas Recirculation (EGR) and that the effect can be increased by heating the intake air. An old engine before the current emission standard was converted to dual fuel operation. It was found that these measures ...

1998-12-31

332

Evaluation of new corrosion resistant superheater tubings in high efficiency waste-to-energy plants  

Energy Technology Data Exchange (ETDEWEB)

In order to develop new corrosion resistant superheater tubes capable of functioning efficiency under temperature and pressure conditions of 500 C and 100 ata used in high efficient waste-to-energy (WTE) plants, field corrosion tests were conducted on eight single tube materials and two welded overlay materials at metal temperatures of 450 C and 550 C for 700 and 3,000 hours, respectively, in three typical japanese waste incineration plants. The test results indicate that austenitic alloys containing higher concentrations of [Cr + Ni + Mo] show excellent corrosion resistant properties and new alloys of JHN24 and HR30M have good corrosion resistance. The different corrosion rate found for each of the three plants could be explained by differences in the severity of corrosion factors, such as, gas temperature, concentration of molten salts due to Cl content of deposits, and heavy metal [ZnO + PbO] content etc. It was also confirmed that the corrosion rate of ...

1997-08-01

333

Estimations of population doses and risk estimates from occupational exposures in Japan, 1978, 2  

International Nuclear Information System (INIS)

The population doses and risks of stochastic effects from occupational exposures in Japan in 1978 were estimated on the basis of a nation-wide survey. The survey was conducted on annual collective dose equivalents by sex, age group and type of radiation work for about 82,500 workers other than the workers in nuclear power stations. The data on the workers in nuclear power stations were obtained from the offitial publication of the Japan Nuclear Safety Commission. The total number of workers except for nuclear power stations was estimated to be about 170,000 persons. Radiation works were subdivided as follows: medical works including dental; nondestructive inspectional; non-atomic energy industrial; research and educational; atomic energy industrial and nuclear power industrial. The annual collective dose equivalents were estimated to be about 6,000 man rem for medical workers, 450 man rem for non-destructive inspectional, 450 man rem for non-atomic energy industrial and 13,300 man rem ...

1981-01-01

334

Corrosion of stainless steels in 20 to 75% nitric acid. Final report. Korrosion von Chrom-Nickel-(Molybdaen)-Staehlen in unterazeotroper und azeotroper Salpetersaeure. Schlussbericht  

Energy Technology Data Exchange (ETDEWEB)

A series of stainless austenitic and ferritic materials was exposed for 100 days to boiling nitric acid which contained no corrosion products; the corrosion rates and depths of the grain boundary attack were observed. - Provided the structure is precipitation-free, the following are suitable for long-term exposure; the austenitic steels X 2 CrNi 19 11, X 1 CrNi 25 21, X 1 CrNiMoN 25 22 2 and X 1 NiCrMoCu 31 27 4, the practically Mo-free and Cu-free development steel X 1 NiCr 31 27, and the highly Mo-alloyed variant X 1 NiCrMoCu 31 27 5. - In the case of alloy NiCr21Mo it is advisable to limit the concentration and/or temperature of the nitric acid. - The 'superferrite' X 1 CrNiMoNb 28 4 2, the Japanese steel X 1 CrNiNb 30 2 and the austenitic steels X 2 CrNiMoN 17 13 3 and X 1 CrNiMoN 25 22 2 in the version with high nickel content are unsuitable. The decisive factor affecting the surface-removal rates is the chromium content of the material. The ...

1988-01-01

335

Boiling water reactors, pressurized water reactors, supercritical water reactors; Reacteurs a eau bouillante, a eau pressurisee, ou a eau supercritique  

Energy Technology Data Exchange (ETDEWEB)

This article gives an account of the recent development of light water reactors new concepts in the world. Different projects are being studied. The CE80+ from Combustion Engineering (CE) is a 1350 MWe-PWR-type reactor whose primary circuit is confined in a spherical metallic containment. This reactor was certified by NRC (national regulatory commission) in mid-1996. The APWR (advanced pressurized water reactor) is developed by MHI (Mitsubishi heavy industries) in a collaboration with Westinghouse, this PWR-type reactor fitted with 4 loops derived from the SP90 model that was developed by Westinghouse during the eighties. 2 units of ABWR (advanced boiling water reactor) were commissioned in Japan in 1996 and 1997, ABWR was certified by NRC in mid-1996. The BWR90+ is developed by ABB-atom (Sweden) and it represents a cautious advanced version of the BWR75. Passive reactors are reactors that rely only on potential energy (compressed gas, gravitational flow or electric batteries) to feed ...

2001-07-01

336

Boiling flow instabilities in parallel channels with enhanced heat transfer  

International Nuclear Information System (INIS)

During the last two decades, the demand for higher heat transfers in the heat exchangers has kept increasing. These high heat transfer rates can be obtained by using two-phase flows, or heat transfer augmented surfaces, or in some cases, both. Thus, the boiling flows and the associated two-phase flow instabilities have been studied by many investigators. Most of the work in boiling flows has been concentrated on single channel upflow systems or on parallel channel systems with plain heat transfer surfaces. The boiling flow instabilities in multi-channel systems should be covered to a greater extent, studying the effects of various parameters, such as inlet and outlet restriction, mass flow rates, the property variations, heat transfer coefficients, equal and unequal heat inputs on the stability. Also, the mathematical modeling needs to be developed for the parallel channel system to take into account the above mentioned variables. The research on two-phase flow instabilities in ...

1985-10-01

337

Biological assessments of a mixture of endocrine disruptors at environmentally relevant concentrations in water following UV/H{sub 2}O{sub 2} oxidation  

Energy Technology Data Exchange (ETDEWEB)

Numerous studies have investigated degradation of individual endocrine disrupting compounds (EDCs) in lab or natural waters. However, natural variations in water matrices and mixtures of EDCs in the environment may confound analysis of the treatment efficiency. Because chemical based analytical methods cannot represent the combined or synergistic activities between water quality parameters and/or the EDC mixtures at environmentally relevant concentrations ({mu}g L{sup -1}-ng L{sup -1}), bioanalytical assessments of residual estrogenic activity in treated water were used to evaluate the performance of the UV based advanced oxidation process for estrogenic contaminants in water. Four EDCs including estradiol (E{sub 2}), ethinyl estradiol (EE{sub 2}), bisphenol-A (BPA) and nonylphenol (NP) were spiked individually or as a mixture at {mu}g L{sup -1}-ng L{sup -1} in laboratory or natural river water. The removal rates of estrogenic activity were quantitatively evaluated by in vitro yeast ...

2007-04-15

338

(Evaluation of the high intensity plasma sputer negative ion source and to test the response of the University of Tsukuba 13-MV tandem accelerator to mA intensity level pulsed mode heavy negative ion beams)  

Energy Technology Data Exchange (ETDEWEB)

A working visit was made to the National Laboratory for High Energy Physics, Tsukuba, Japan, during the time periods May 16, 1988--June 15, 1988 for the purposes of further evaluation of the high intensity plasma sputter negative ion source and to test the response of the University of Tsukuba 13-MV tandem accelerator to mA intensity level pulsed mode heavy negative ion beams. During the visit, the traveler worked in collaboration with Japanese scientists in installing and testing of the source on the University of Tsukuba tandem electrostatic accelerator injector. During the course of preliminary testing of the ion source and prior to actual injection into the accelerator, sparking began in one or more tube sections, which ultimately led to the decision to replace the damaged tube sections. This problem led to postponement of the scheduled tandem accelerator tests. The traveler attended the Seventh International Conference on Ion Implantation Technology held in ...

1988-07-06

339

Use of a convolution/superposition-based treatment planning system for dose calculations in the kilovoltage energy range  

International Nuclear Information System (INIS)

A number of procedures in diagnostic radiology and cardiology make use of long exposures to x-rays from fluoroscopy units. Although numerous studies have been performed to measure or calculate skin dose from these procedures, there have only been a handful of studies to determine the dose to the other organs. This thesis was focused on devising a method to calculate the absorbed dose to underlying tissues and organs. The work was performed in several stages. First, a commercial convolution/superposition-based treatment planning system used in radiation oncology was modified and complemented to make it usable with the low energies of x-rays used in diagnostic radiology. This required generation of energy deposition kernels in the kilovoltage energy range. The kernels were generated using the EGS4 Monte Carlo system of codes and added to the treatment planning system. The treatment planning system was then evaluated for its accuracy of calculations at low energies within homogeneous and ...

2001-03-01

340

The effect of patient shield position on gonad dose during lumbar spine radiography  

Energy Technology Data Exchange (ETDEWEB)

Background: In an effort to standardise radiological practices in the Republic of Ireland, current legislation states that 'written protocols for every type of standard radiological practice shall be established'. In order to fulfil this requirement the Irish Medical Council recommends the protocols issued by the Commission of European Communitees (CEC) for adoption in the country. Whilst this document does provide good guidance with regard to various radiographic factors, patient shielding instructions are notably ambiguous. The aim of this study was to remove some of this ambiguity by defining the optimal method of positioning patient shielding in antero-posterior (AP) and lateral lumbar spine radiographic examinations. These projections were chosen on the basis of their area of coverage being in close to and in some cases including the reproductive organs. They also represent the highest source of collective population dose of any conventional radiographic ...

2010-05-15

341

The effect of patient shield position on gonad dose during lumbar spine radiography  

International Nuclear Information System (INIS)

Background: In an effort to standardise radiological practices in the Republic of Ireland, current legislation states that 'written protocols for every type of standard radiological practice shall be established'. In order to fulfil this requirement the Irish Medical Council recommends the protocols issued by the Commission of European Communitees (CEC) for adoption in the country. Whilst this document does provide good guidance with regard to various radiographic factors, patient shielding instructions are notably ambiguous. The aim of this study was to remove some of this ambiguity by defining the optimal method of positioning patient shielding in antero-posterior (AP) and lateral lumbar spine radiographic examinations. These projections were chosen on the basis of their area of coverage being in close to and in some cases including the reproductive organs. They also represent the highest source of collective population dose of any conventional radiographic examination carried out in ...

2010-05-01

342

Study of X-ray filter and peak kilovoltage in Fuji computed radiography in regard to the detection of simulated pulmonary nodules  

Energy Technology Data Exchange (ETDEWEB)

To determine a suitable combination of X-ray filter and tube kilovoltage for Fuji Computed Radiography (FCR), provide better detection of pulmonary nodules, and reduce patient exposure, we compared observer performance with different X-ray filters and tube voltages. Radiographs were obtained with a copper filter backed by aluminium, with a tungsten filter backed by yttrium and aluminium, and with a lead filter backed by yttrium and aluminium, at both 100 kVp and 135 kVp. Observer performance in detecting simulated lung nodules, which were placed on the posterior aspect of a chest phantom, was compared using receiver operating characteristic (ROC) techniques for each combination of the X-ray filter and tube voltage. The results of the study indicated that (1) nodule detection was superior for the images obtained with 135 kVq as compared with 100 kVp; (2) approximately equal detection rates were obtained for the three X-ray filter sets, although results with the ...

1994-10-01

343

Study of X-ray filter and peak kilovoltage in Fuji computed radiography in regard to the detection of simulated pulmonary nodules  

International Nuclear Information System (INIS)

To determine a suitable combination of X-ray filter and tube kilovoltage for Fuji Computed Radiography (FCR), provide better detection of pulmonary nodules, and reduce patient exposure, we compared observer performance with different X-ray filters and tube voltages. Radiographs were obtained with a copper filter backed by aluminium, with a tungsten filter backed by yttrium and aluminium, and with a lead filter backed by yttrium and aluminium, at both 100 kVp and 135 kVp. Observer performance in detecting simulated lung nodules, which were placed on the posterior aspect of a chest phantom, was compared using receiver operating characteristic (ROC) techniques for each combination of the X-ray filter and tube voltage. The results of the study indicated that 1) nodule detection was superior for the images obtained with 135 kVq as compared with 100 kVp; 2) approximately equal detection rates were obtained for the three X-ray filter sets, although results with the ...

1994-01-01

344

Stochastic risk estimation from medical x-ray diagnostic examinations, 2  

International Nuclear Information System (INIS)

The risks of genetic, leukemia and malignant diseases from medical X-ray diagnostic examinations were estimated using the frequency of radiographic and fluoroscopic exposures per diagnostic examination, child expectancy, leukemia and malignancy significant factors, and using a weighting factor determined on the basis of data concerning the cancer mortality among atomic bomb survivors in Nagasaki and of a recommendation of International Commission of Radiological Protection. The organ or tissue doses with respect to the stochastic risks were determined with ionization chambers and thermoluminescent dosimeters placed at the positions of the organs or tissues in a RANDO woman phantom which was exposed to diagnostic X-rays according to technical factors of typical radiographic and fluoroscopic examinations obtained from a nationwide survey. The resultant risks by age-group and type of radiographic and fluoroscopic examination are tabulated in terms of risk level of ...

1981-01-01

345

Reintrusion of silicic magma chambers by mafic dike complex: evidence from the northern Semail ophiolite  

Energy Technology Data Exchange (ETDEWEB)

Late plagiogranite bodies in the Semail ophiolite have been previously suggested to represent late stage fractionates within an episodic spreading center magma chamber or the roots of seamount chains. Field and lab observations suggest that these late silicic magma chambers represent zones of repeated injection by dikes of intermediate to mafic composition. Multiple generations of intrusion, partial resorption and reintrusion are preserved in the plagiogranite as 1) relict phantom xenoliths, 2) angular xenoliths with quartz-rich margins, 3) deformed fine-grained dikes with distinct chilled margins, and 4) planes of rectangular blocks with cuspate margins or ellipsoids of similar fine grained mafic materials. The blocks and ellipsoids are actually dismembered mafic dikes that chilled by intruding a cooler silicic liquid and were either thermally fractured or pinched out. All of the dikes are hydrothermally altered to assemblages including amph., qtz., epi., preh., ...

1985-01-01

346

Radiation dosimetry of "1"1"1In-oxinate labelled leucocytes  

International Nuclear Information System (INIS)

The patients studied were referred for routine abscess localization with indium-111 labelled autologous leukocytes. One series (n=15) was studied at 1 day after reinjection of labelled cells and a second series (n=9) was studied between 4 hours and 4 days after reinjection of labelled cells. The leukocytes were isolated by a gravity sedimentation method and labelled with In-111 oxinate according to Roevekamp and co-workers. The labelled cell suspension administered to the patient contained between 11 and 15 MegaBq (300-400 microCi). The indium-111 concentration in the liver and spleen was quantitated using a scintillation camera and an on-line computer system. Phantom studies were carried out to obtain conversion factors from geometric mean counts to MegaBq of activity for both liver and spleen. Once determined, the amount of activity in liver and spleen was corrected for physical decay of In-111 and expressed as a percentage of the administered activity. ...

1982-06-25

347

Proceedings of clinical SPECT [single photon emission computed tomography] symposium  

International Nuclear Information System (INIS)

It has been five years since the last in-depth American College of Nuclear Physicians/Society of Nuclear Medicine Symposium on the subject of single photon emission computed tomography (SPECT) was held. Because this subject was nominated as the single most desired topic we have selected SPECT imaging as the basis for this year's program. The objectives of this symposium are to survey the progress of SPECT clinical applications that have taken place over the last five years and to provide practical and timely guidelines to users of SPECT so that this exciting imaging modality can be fully integrated into the evaluation of pathologic processes. The first half was devoted to a consideration of technical factors important in SPECT acquisition and the second half was devoted to those organ systems about which sufficient clinical SPECT imaging data are available. With respect to the technical aspect of the program we have selected the key areas which demand awareness and attention in order ...

1986-09-22

348

Preliminary study of metabolic radiotherapy with {sup 188}Re via small animal imaging  

Energy Technology Data Exchange (ETDEWEB)

{sup 188}Re is a {beta}{sup -} (Emax=2.12 MeV) and {gamma} (155 keV) emitter. Since its chemistry is similar to that of the largely employed tracer, {sup 99m}Tc, molecules of hyaluronic acid (HA) have been labelled with {sup 188}Re to produce a target specific radiopharmaceutical. The radiolabeled compound, i.v. injected in healthy mice, is able to accumulate into the liver after a few minutes. To study the effect of metabolic radiotherapy in mice, we have built a small gamma camera based on a matrix of YAP:Ce crystals, with 0.6x0.6x10 mm{sup 3} pixels, read out by a R2486 Hamamatsu PSPMT. A high-sensitivity 20 mm thick lead parallel-hole collimator, with hole diameter 1.5 mm and septa of 0.18 mm, is placed in front of the YAP matrix. Preliminary results obtained with various phantoms containing a solution of {sup 188}Re and with C57 black mice injected with the {sup 188}Re-HA solution are presented. To increase the space resolution and to obtain two orthogonal ...

2006-01-15

349

Population doses from beam-therapy in Japan, 1978, 3  

International Nuclear Information System (INIS)

As a series of estimations of population doses and of risk estimates from medical exposures in Japan, the malignancy significant dose (MSD) and the fatal malignant risk from beam therapy were estimated based on a nationwide survey of radiotherapeutic treatments, using a malignancy significant factor and a weighting factor determined from the data on the cancer mortality among the atomic bomb survivors in Nagasaki. The effective dose was defined as a sum of the product of the weighting factor and the organ or tissue doses with respect to the malignant diseases. The organ or tissue doses were determined with ionization chambers placed at the positions of their center in a MixDp-phantom simulated lung tissues by a block of cork, using a telecobalt unit, a conventional X-ray unit and a medical linear accelerator. The organ or tissue doses were categorized into three dose components; namely 1) dose from useful beams; 2) scattered radiation dose from irradiated materials ...

1981-01-01

350

Performance study of teleradiology network systems with CRT monitors. ROC analysis of an observation study of simulated lung nodules  

International Nuclear Information System (INIS)

To evaluate the diagnostic performance of commercially available CRT monitors used in a teleradiology system by determining the rate of detection of simulated lung nodules. Three types of CRT monitors were tested in the observation study. They had matrix sizes of 1024 x 768 (16 inches, color), 1024 x 768 (20 inches, color) and 1600 x 1125 (24 inches, black and white). Twenty chest radiographs were obtained by Fuji computed radiography (FCR) of an anthropomorphic chest phantom with ten simulated nodules on its surface. These FCR films were digitized by a film digitizer with 125 DPI (1024 x 1024 matrix sizes) and 12 bit gray scales, and the image data were transferred from Shinshu University Hospital to other hospitals where interpretation was carried out by the radiologists. Ten radiologists of three hospitals were asked to interpret independently both the original FCR films and the images shown on the CRT monitors and to indicate the presence or absence of ...

351

Monte Carlo-based investigation of effect of inhomogeneity in brachytherapy dose calculation - Part I  

International Nuclear Information System (INIS)

Brachytherapy refers to short distance treatment of cancer with radiation from small, encapsulated radionuclide sources. This type of treatment is given by placing sources directly into or near the volume to be treated. The dose is then delivered continuously, either over a short period of time (temporary implants) or over the lifetime of the source to a complete decay (permanent implants). This technique is extensively used in the treatments of gynecological, breast, prostate, head and neck, and other soft tissue cancers. The clinical outcomes of this treatment depend on accurate dosimetry and dose delivery. The patient is generally considered to be water equivalent. So the treatment planning system software generally is based on measured or calculated dose distributions in homogenous water medium. In real situation, the treatment volume is not homogenous water medium, but it is a heterogeneous medium consisting of bone, soft tissue, lung, air etc. For better understanding we present ...

2009-04-01

352

Monte Carlo treatment planning for photon and electron beams  

International Nuclear Information System (INIS)

During the last few decades, accuracy in photon and electron radiotherapy has increased substantially. This is partly due to enhanced linear accelerator technology, providing more flexibility in field definition (e.g. the usage of computer-controlled dynamic multileaf collimators), which led to intensity modulated radiotherapy (IMRT). Important improvements have also been made in the treatment planning process, more specifically in the dose calculations. Originally, dose calculations relied heavily on analytic, semi-analytic and empirical algorithms. The more accurate convolution/superposition codes use pre-calculated Monte Carlo dose 'kernels' partly accounting for tissue density heterogeneities. It is generally recognized that the Monte Carlo method is able to increase accuracy even further. Since the second half of the 1990s, several Monte Carlo dose engines for radiotherapy treatment planning have been introduced. To enable the use of a Monte Carlo treatment planning (MCTP) dose ...

2007-04-01

353

Implementation of FFT convolution and multigrid superposition models in the FOCUS RTP system  

International Nuclear Information System (INIS)

In radiotherapy treatment planning, convolution/superposition algorithms currently represent the best practical approach for accurate photon dose calculation in heterogeneous tissues. In this work, the implementation, accuracy and performance of the FFT convolution (FFTC) and multigrid superposition (MGS) algorithms are presented. The FFTC and MGS models use the same 'TERMA' calculation and are commissioned using the same parameters. Both models use the same spectra, incorporate the same off-axis softening and base incident lateral fluence on the same measurements. In addition, corrections are explicitly applied to the polyenergetic and parallel kernel approximations, and electron contamination is modelled. Spectra generated by Monte Carlo (MC) modelling of treatment heads are used. Calculations using the MC spectra were in excellent agreement with measurements for many linear accelerator types. To speed up the calculations, a number of calculation techniques were implemented, ...

2000-04-01

354

High-resolution "1H magnetic resonance spectroscopy imaging at 1.5 and 3 Tesla of the human brain: development of techniques and applications for patients with primary brain tumors and multiple sclerosis  

International Nuclear Information System (INIS)

The aim of this work was to develop several strategies and software-packages for the evaluation of in-vivo-data of the human brain, which were acquired with high-resolution 1H-MRSI at 1.5 and 3 T. Several studies involving phantoms, volunteers and patients were performed. Quality assurance studies were conducted in order to evaluate the reproducibility of the applied MR-techniques at both field strengths. A qualitative comparison-study between MRSI-data from a 1.5 T clinical MR-scanner and a 3 T research MR-scanner showed the advantages of the more advanced MRSI sequences and higher field strength (3 T). A study involving patients with primary brain tumours (gliomas) was performed in cooperation with the Department of Neurosurgery (University of Erlangen-Nuremberg). The methods developed in the course of this study, such as the integration of MRS-data into a stereotactic-system, the segmentation of metabolic maps and the correlation with histopathological findings ...

355

Estimate of the scatter component in SPECT  

Energy Technology Data Exchange (ETDEWEB)

Analytical expressions that describe the dependence of slopes and amplitudes of the scatter distribution functions (SDF) on source depth and media density are used to estimate a scatter component in SPECT projection data. Since the ratio of detected scattered to total photons (S/T), SDF amplitude and slope depend strongly on line source length (SL) used to obtain SDFs, we compared estimated scattered components using SDFs, obtained for lengths of 2-21 cm. At 10 cm source depth, S/T changes from 0.19 to 0.36 when SL changes from 2 to 21 cm. Scatter amplitude`s dependence on source depth (d) in water was described by 6.38e{sup -0.186d} for a 2 cm and 16.15e{sup -0.129d} for a 21 cm SL. Slope was described by 0.292d{sup -0.601} for a cm SL and by 0.396d{sup -0.82} for a 21 cm SL. The estimated scatter components are compared with simulated SPECT projection data obtained with Monte Carlo modeling of six hot spheres placed in a cylindrical water filled phantom. The ...

1996-12-31

356

Collective effective dose equivalent, population doses and risk estimates from occupational exposures in Japan  

Energy Technology Data Exchange (ETDEWEB)

Collective dose equivalent and population dose from occupational exposures in Japan, 1988 were estimated on the basis of a nationwide survey. The survey was conducted on annual collective dose equivalents by sex, age group and type of radiation work for about 0.21 million workers except for the workers in nuclear power stations. The data on the workers in nuclear power stations were obtained from the official report of the Japan Nuclear Safety Commission. The total number of workers including nuclear power stations was estimated to be about 0.26 million. Radiation works were subdivided as follows: medical works including dental; non-atomic energy industry; research and education; atomic energy industry and nuclear power station. For the determination of effective dose equivalent and population dose, organ or tissue doses were measured with a phantom experiment. The resultant doses were compared with the doses previously calculated using a chord length technique and ...

1993-05-01

357

Collective effective dose equivalent, population doses and risk estimates from occupational exposures in Japan  

International Nuclear Information System (INIS)

Collective dose equivalent and population dose from occupational exposures in Japan, 1988 were estimated on the basis of a nationwide survey. The survey was conducted on annual collective dose equivalents by sex, age group and type of radiation work for about 0.21 million workers except for the workers in nuclear power stations. The data on the workers in nuclear power stations were obtained from the official report of the Japan Nuclear Safety Commission. The total number of workers including nuclear power stations was estimated to be about 0.26 million. Radiation works were subdivided as follows: medical works including dental; non-atomic energy industry; research and education; atomic energy industry and nuclear power station. For the determination of effective dose equivalent and population dose, organ or tissue doses were measured with a phantom experiment. The resultant doses were compared with the doses previously calculated using a chord length technique and ...

1993-01-01

358

Canon's flat-panel detector  

International Nuclear Information System (INIS)

We measured and evaluated digital, pre-sampling and overall imaging properties (characteristic curve, modulation transfer function (MTF), Wiener spectrum (WS), noise equivalent quanta (NEQ)) for Cannon's flat-panel detector (FPD), Fuji computed radiography (FCR) and screen-film (S/F) systems, respectively. First, the digital and overall characteristic curves of FPD and FCR systems were more wide dynamic range than that of the S/F system. Second, the pre-sampling and overall MTF of FPD system were better than those of FCR system a little at lower spatial frequencies than 0.8 mm"-"1, but the overall MTF of FPD and FCR systems were worse than that of S/F system a little at all spatial frequencies. Third, the digital and overall WS of FPD system were similar or better than those of FCR system, but the overall WS of FPD and FCR systems were worse than that of S/F system. Fourth, the pre-sampling and overall NEQ of FPD system were better than those of FCR system a little at lower spatial ...

2002-12-01

359

Canon's flat-panel detector  

Energy Technology Data Exchange (ETDEWEB)

We measured and evaluated digital, pre-sampling and overall imaging properties (characteristic curve, modulation transfer function (MTF), Wiener spectrum (WS), noise equivalent quanta (NEQ)) for Cannon's flat-panel detector (FPD), Fuji computed radiography (FCR) and screen-film (S/F) systems, respectively. First, the digital and overall characteristic curves of FPD and FCR systems were more wide dynamic range than that of the S/F system. Second, the pre-sampling and overall MTF of FPD system were better than those of FCR system a little at lower spatial frequencies than 0.8 mm{sup -1}, but the overall MTF of FPD and FCR systems were worse than that of S/F system a little at all spatial frequencies. Third, the digital and overall WS of FPD system were similar or better than those of FCR system, but the overall WS of FPD and FCR systems were worse than that of S/F system. Fourth, the pre-sampling and overall NEQ of FPD system were better than those of FCR system a little at ...

2002-12-01

360

ANALYSIS OF ACCELERATOR BASED NEUTRON SPECTRA FOR BNCT USING PROTON RECOIL SPECTROSCOPY  

Energy Technology Data Exchange (ETDEWEB)

Boron Neutron Capture Therapy (BNCT) is a promising binary treatment modality for high-grade primary brain tumors (glioblastoma multiforme, GM) and other cancers. BNCT employs a boron-10 containing compound that preferentially accumulates in the cancer cells in the brain. Upon neutron capture by {sup 10}B energetic alpha particles and triton released at the absorption site kill the cancer cell. In order to gain penetration depth in the brain Fairchild proposed, for this purpose, the use of energetic epithermal neutrons at about 10 keV. Phase I/II clinical trials of BNCT for GM are underway at the Brookhaven Medical Research Reactor (BMRR) and at the MIT Reactor, using these nuclear reactors as the source for epithermal neutrons. In light of the limitations of new reactor installations, e.g. cost, safety and licensing, and limited capability for modulating the reactor based neutron beam energy spectra alternative neutron sources are being contemplated for wider implementation of this ...

1998-11-06

361

A study on the mineral density of the lumbar vertebral bone in children of metabolic disorders and control using single energy quantitative CT  

Energy Technology Data Exchange (ETDEWEB)

A cross sectional study on the mineral density of the 3rd lumbar vertebral trabecular bone was carried out in 123 children less than 15 years old, comprising 44 controls, and 79 patients affected with conditions which are at risk for developing metabolic derangement of skeletal bone (34 patients taking antiepileptic drugs (AED), 29 undergoing glucocorticoid (GC) therapy and 16 bedridden patients), by using quantitative computed tomography (QCT) with a CaCO{sub 3} phantom. Serum Ca and alkaline-phosphatase (Alp) levels were measured at the time of QCT examinations in all. The results obtained were as follows: The QCT values in the control children showed neither age dependency nor a sexual difference before puberty. The QCT values in each group showed significant difference with one another; the control group>the AED group>the GC group>the bedridden group (p<0.05{approx}0.005). The serum Ca levels in each pathology group were significantly lower than ...

1991-06-01

362

A revised dosimetric model of the adult head and brain  

Energy Technology Data Exchange (ETDEWEB)

During the last decade, new radiopharmaceutical have been introduced for brain imaging. The marked differences of these tracers in tissue specificity within the brain and their increasing use for diagnostic studies support the need for a more anthropomorphic model of the human brain and head. Brain and head models developed in the past have been only simplistic representations of this anatomic region. For example, the brain within the phantom of MIRD Pamphlet No. 5 Revised is modeled simply as a single ellipsoid of tissue With no differentiation of its internal structures. To address this need, the MIRD Committee established a Task Group in 1992 to construct a more detailed brain model to include the cerebral cortex, the white matter, the cerebellum, the thalamus, the caudate nucleus, the lentiform nucleus, the cerebral spinal fluid, the lateral ventricles, and the third ventricle. This brain model has been included within a slightly modified version of the head ...

1996-06-01

363

A revised dosimetric model of the adult head and brain  

International Nuclear Information System (INIS)

During the last decade, new radiopharmaceutical have been introduced for brain imaging. The marked differences of these tracers in tissue specificity within the brain and their increasing use for diagnostic studies support the need for a more anthropomorphic model of the human brain and head. Brain and head models developed in the past have been only simplistic representations of this anatomic region. For example, the brain within the phantom of MIRD Pamphlet No. 5 Revised is modeled simply as a single ellipsoid of tissue With no differentiation of its internal structures. To address this need, the MIRD Committee established a Task Group in 1992 to construct a more detailed brain model to include the cerebral cortex, the white matter, the cerebellum, the thalamus, the caudate nucleus, the lentiform nucleus, the cerebral spinal fluid, the lateral ventricles, and the third ventricle. This brain model has been included within a slightly modified version of the head ...

1996-07-21

364

A gradient feature weighted Minimax algorithm for registration of multiple portal images to 3DCT volumes in prostate radiotherapy  

International Nuclear Information System (INIS)

Purpose: To develop an accurate, fast, and robust algorithm for registering portal and computed tomographic (CT) images for radiotherapy using a combination of sparse and dense field data that complement each other. Methods and Materials: Gradient Feature Weighted Minimax (GFW Minimax) method was developed to register multiple portal images to three-dimensional CT images. Its performance was compared with that of three others: Minimax, Mutual Information, and Gilhuijs' method. Phantom and prostate cancer patient images were used. Effects of registration errors on tumor control probability (TCP) and normal tissue complication probability (NTCP) were investigated as a relative measure. Results: Registration of four portals to CTs resulted in 30% lower error when compared with registration with two portals. Computation time increased by nearly 50%. GFW Minimax performed the best, followed by Gilhuijs' method, the Minimax method, and Mutual Information. Conclusions: ...

2006-06-01

365

The study of technical error analysis on BMD using DEXA  

International Nuclear Information System (INIS)

This study was conducted to search for the type of technical error in DEXA (dual-energy X-ray absorptiometry) and the effect of error to measurement of BMD. The changes of BMD (g/cm2, T-score) by patients information (Age, Weight, Height, Manopause age) input error and Confirming ROI error were investigated. Using spine phantom, we canned 10 times by age (5, 10), weight (10, 20 kg), height (5, 10 cm), manopause age (5, 10) increase and decrease respectively. Scanning region (L-spine, femur, Forearm) of 10 patients was calculated by changing ROI respectively. Analysis of difference for mean (precision 1%) were carried out. There error of patient information (Age, Weight, Height, Manopause age) was not changed differently. In confirming ROI, the BMD and T-score of L-spine involving T-12 was decreased to 0.063 g/cm2, 0.3 and involving L-5 increased to 0.077 g/cm2, 0.5. In narrowing 1 cm of vertical line of ROI, the BMD and T-score decreased to 0.006 g/cm2, 0.1 and in ...

2006-12-01

366

In vitro examination of the visibility of 11 stent catheters with real-time MR imaging; In-vitro-Untersuchung der Sichtbarkeit von 11 Stentkathetern unter Echtzeit-MR-Kontrolle  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To evaluated artifacts of unexpended stents and to determine their exact position for MR-guided percutaneous transluminal angioplasty using real-time sequences. Materials and Methods: By using an in vitro model, 11 unexpended stents - 9 nitinol, 1 stainless steel, and 1 cobalt alloy - were investigated by MR. Each stent was studied in a vessel-phantom filled with saline solution. Imaging was performed using five different realtime sequences: fast low angle shot (Flash 2D), fast imaging with steady precession (true FISP, FISP, interactive true FISP) and segmented echo planar imaging (seg. EPI). Artifacts of the introducer system and the stent were calculated by four blinded radiologists (scale: 1 - artifacts, making an excellent contribution to visualization; 2 - artifacts, making mainly a contribution to visualization; 3 - artifacts, making no contribution to visualization). Furthermore, an evaluation of the visibility of the tip of the stent-catheter and ...

2004-09-01

367

Digital image intensifier radiography: first experiences with the DSI (Digital Spot Imaging); Moeglichkeiten der digitalen Bildverstaerkerradiographie am Beispiel des Digital Spot Imaging (DSI)  

Energy Technology Data Exchange (ETDEWEB)

We performed a comparative study of digitally and conventionally acquired images in gastrointestinal examinations. Radiation dose and spatial resolution were determined in a water phantom. In 676 examinations with either conventional or digital imaging (system: Diagnost 76, DSI) the number of images and the duration of the fluoroscopy time were compared. 101 examinations with digital as well as conventional documentation were evaluated by using 5 criteria describing the diagnostic performance. The entrance dose of the DSI is 12% to 36% of the film/screen system and the spatial resolution of the DSI may be better than that of a film/screen system with a speed of 200. The fluoroscopy time shows no significant difference between DSI and the film/screen technique. In 2 of 4 examination modes significantly more images were produced by the DSI. With exception of the criterion of edge sharpness, DSI yields a significantly inferior assessment compared with the film/screen ...

1995-10-01

368

A deterministic partial differential equation model for dose calculation in electron radiotherapy  

International Nuclear Information System (INIS)

High-energy ionizing radiation is a prominent modality for the treatment of many cancers. The approaches to electron dose calculation can be categorized into semi-empirical models (e.g. Fermi-Eyges, convolution-superposition) and probabilistic methods (e.g. Monte Carlo). A third approach to dose calculation has only recently attracted attention in the medical physics community. This approach is based on the deterministic kinetic equations of radiative transfer. We derive a macroscopic partial differential equation model for electron transport in tissue. This model involves an angular closure in the phase space. It is exact for the free streaming and the isotropic regime. We solve it numerically by a newly developed HLLC scheme based on Berthon et al (2007 J. Sci. Comput. 31 347-89) that exactly preserves the key properties of the analytical solution on the discrete level. We discuss several test cases taken from the medical physics literature. A test case with an academic ...

2010-07-07

369

64-slice multidetector coronary CT angiography: in vitro evaluation of 68 different stents  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to test a large sample of different coronary artery stents using four image reconstruction approaches with respect to lumen visualization, lumen attenuation, and image noise in 64-slice multidetector-row computed tomography (MDCT) in vitro and to provide a catalogue of currently used coronary artery stents when imaged with state-of the-art MDCT. We examined 68 different coronary artery stents (57 stainless steel, four cobalt-chromium, one cobalt-alloy, two nitinol, four tantalum) in a coronary artery phantom (vessel diameter 3 mm, intravascular attenuation 250 HU, extravascular density -70). Stents were imaged in axial orientation with standard parameters: 32x0.6 collimation, pitch 0.24, 680 mAs, 120 kV, rotation time 0.37 s. Four different image reconstructions were obtained with varying convolution kernels and section thicknesses: (1) soft, 0.6 mm, (2) soft, 0.75, (3) medium soft, 0.6, and (4) stent-optimized sharp, 0.6. To evaluate ...

2006-04-15

370

ALOS satellite imagery utilizations for safeguards  

International Nuclear Information System (INIS)

This paper introduces examples of satellite imageries analysis and utilizations for safeguards activities. Recently, many kinds of satellite imageries are available in the world i.e., high-spatial resolution, multi- and hyper-spectral, multi-function, and multi-polarization radars. The problem is that how to obtain the required information from these digital images. The Japan Aerospace Exploration Agency (JAXA) has successfully launched the Advanced Land Observing Satellite (ALOS, the nickname is 'Daichi') on 24th January, 2006. The mission objectives are cartography, regional observation, disaster monitoring etc. ALOS has three instruments, PRISM, AVNIR-2, and PALSAR, to achieve these objectives. An overview of ALOS is provided. ALOS follows the Japanese Earth Resources Satellite- 1 (JERS-1) and the Advanced Earth Observing Satellite (ADEOS) and utilizes advanced land-observing technology. ALOS is fling in a Sun-synchronous orbit with an inclination angle of 98.16 ...

2006-10-16

371

Retrospective individual dosimetry using luminescence and EPR after radiation accidents  

International Nuclear Information System (INIS)

In areas where radiation dose monitoring has not been performed, it is essential to use material available in the environment be able to rapidly assess doses to individuals for immediate emergency medical care or for general estimation of the radiological consequences. It was shown that certain types of telephone cards containing microchips have the potential to be used as individual radiation dosimeters in emergency situations to detect doses over 250 mGy by luminescence measurements. In order to understand the dosimetric properties of chip cards, the components obtained from INFINIEON Company at various stages of production were used for luminescence measurements. It is found that the protecting layer used above the chips so called 'globe top' is the main source of radiation induced signal in chip cards. The globe top produced by INFINIEON at that stage is found to contain SiO2 and Epoxy. In order to improve the dosimetric properties of the chip cards, the raw material of the globe ...

372

MR-based volumetric analysis of small tumor volumes: accuracy of phantom examinations of simulated eye tumors; Evaluierung der MR-Volumetrie kleiner Volumina am Beispiel von Augentumoren mittels Phantomuntersuchungen  

Energy Technology Data Exchange (ETDEWEB)

Purpose: The determination of tumor volume in ocular tumors is very important for the planning and success of radiation therapy. This study uses an animal model to evaluate the accuracy of MR-based volumetry of ocular tumors. Materials and methods: In a total of 25 porcine eyes obtained from the slaughterhouse, ocular tumors were produced by injecting a mixture of hand creme and Gd-DTPA under ophthalmoscopic guidance. The injected volume varied between 0.05 ml and 2.7 ml. The eyes were examined with a 1.5 Tesla scanner and a 4 cm circular surface coil especially developed for ocular MRI. After data transfer to a separate workstation, volumetric analysis was carried out by three independent radiologists using semiautomated software. The determined volume was compared with the injected volume. Results: Of the 25 prepared porcine eyes, 23 were suitable for volumetric analysis. The injection of the mixture of hand creme and GD-DTPA produced two different types of tumors. ...

2003-07-01