WorldWideScience
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Laparoscopic sigmoid resection for diverticular disease has no advantages over open approach: midterm results of a randomized controlled trial  

British Library Electronic Table of Contents (United Kingdom)

Purpose Elective laparoscopic sigmoid resection (LSR) for symptomatic diverticular disease is supposed to have significant short-term advantages compared to open surgery (open sigmoid resection (OSR)). This opinion is rather based on inferences from trials on colonic resections for malignant diseases or minor laparoscopic surgery. This randomized controlled trial was conducted to compare quality of life as well as morbidity and clinical outcome after LSR vs. OSR following a midterm follow-up period. Methods Patients presenting with a symptomatic sigmoid diverticular disease stage II/III (Stock/Hansen) were randomly allocated to LSR or OSR in a prospective multicenter trial. Endpoints included the quality of life assessed with a standardized questionnaire, postoperative mortality, and compl...

2011-01-01

2

The use of biodegradable polylactic acid barrier materials in the treatment of grade II periodontal furcation defects in humans--Part II: A multicenter investigative surgical study.  

Science.gov (United States)

This study evaluated whether differences in design of 3-dimensional polylactic acid barriers (EPi-Guide and Guidor) would influence hard tissue results in the treatment of Grade II furcations in humans. A multicenter study was conducted, using 40 patients with moderate to advanced bilateral chronic adult periodontitis of the mandibular first or second molars. After flap access, debridement, and root preparation, surgical bone level measurements were taken and membranes were placed on a random basis. Surgical reentry occurred at 1 year. Data collected from all 3 investigative centers were pooled and analyzed using an analysis of variance appropriate for a counterbalancing design. Both barrier materials resulted in significant gains of attachment level and defect reduction. The composite reduction in the vertical component of the osseous defects was greater in the sites treated with Epi-Guide as compared to those treated with ...

1999-02-01

3

Results of a multicenter trial comparing imipenem/cilastatin to tobramycin/clindamycin for intra-abdominal infections.  

UK PubMed Central (United Kingdom)

We designed a multicenter study to compare tobramycin/clindamycin to imipenem/cilastatin for intra-abdominal infections. We included the Acute Physiology and Chronic Health Evaluation (APACHE II) index...Full Text Available

1990-11-01

4

A randomized controlled trial investigation of a non-stimulant in attention deficit hyperactivity disorder (ACTION): Rationale and design  

UK PubMed Central (United Kingdom)

BackgroundThe ACTION study (Attention deficit hyperactivity disorder Controlled Trial Investigation Of a Non-stimulant) is a multi-center, double-blind, randomized...Full Text Available

5

Diet and lifestyle interventions in postpartum women in China: study design and rationale of a multicenter randomized controlled trial  

UK PubMed Central (United Kingdom)

Background"Doing the month", or "sitting month", is a traditional practice for postpartum women in China and other Asian countries, which includes some taboos against well-accepted...Full Text Available

6

Irradiation with and without razoxane in the treatment of incompletely resected or inoperable recurrent rectal cancer. Results of a small randomized multicenter study  

Energy Technology Data Exchange (ETDEWEB)

Background and Purpose: In an earlier phase II study, irradiation together with razoxane was shown to improve local control in recurrent rectal cancer. Therefore, the Austrian Society of Radiooncology (OeGRO) initiated a randomized controlled trial in 1992 to compare this combined treatment versus radiation therapy alone. Patients and Methods: Between 1992 and 1999, 36 patients with localized recurrences of rectal cancer were randomized to receive radiotherapy without (group A) or with razoxane (group B). The prognostic variables of the two groups were similar except for a longer median latency period from initial surgery to local recurrence in group A. High-energy photons with daily fractions between 170 and 200 cGy were used. The median total radiation dose was 60 Gy in each group. The patients in group B received a median razoxane dose of 9.6 g (range, 5-12 g). Main outcome measures were local control, overall survival, ...

2007-07-15

7

Radiotherapy quality assurance review in a multi-center randomized trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202  

UK PubMed Central (United Kingdom)

BackgroundThe purpose of this study was to analyze the radiotherapy (RT) quality assurance (QA) assessment in Japan Clinical Oncology Group (JCOG) 0202, which was the first trial...Full Text Available

8

Effect of duration of postherpetic neuralgia on efficacy analyses in a multicenter, randomized, controlled study of NGX-4010, an 8% capsaicin patch evaluated for the treatment of postherpetic neuralgia  

UK PubMed Central (United Kingdom)

BackgroundPostherpetic neuralgia (PHN) is a painful and difficult to treat complication of acute herpes zoster. Current treatment options provide only partial relief and are often...Full Text Available

9

Injection-associated pain in femoral arteriography: A European multicenter study comparing safety, tolerability, and efficacy of iodixanol and iopromide  

International Nuclear Information System (INIS)

Purpose. To evaluate injection-associated pain, safety, and efficacy with the isotonic contrast medium iodixanol (Visipaque 270 mg I/ml) compared with iopromide (Ultravist 300 mg I/ml) in femoral arteriography. Methods. A multicenter, double-blind, randomized, parallel-group clinical investigation was carried out in 54 hospitals in Europe. Of the patients evaluated, 1225 received iodixanol and 1227 iopromide in conventional and/or digital subtraction angiography. Results. The iodixanol group reported statistically significantly less injection-associated pain (0.9%) than the iopromide group (9.5%) (p<0.001). Further, 4.1% in the iodixanol group experienced pain and/or severe heat sensation vs 19.8% in the iopromide group (p<0.001). In the iodixanol group, 1.8% of the patients experienced contrast-related adverse events vs 2.4% in the iopromide group (p=NS). Overall diagnostic information was optimal for 94.1% in the iodixanol group and ...

1997-07-01

10

A randomized, double-blind, placebo-controlled parallel-group study to assess the efficacy and safety of nebivolol, a novel beta-blocker, in patients with mild to moderate hypertension.  

Science.gov (United States)

This double-blind, multicenter, randomized placebo-controlled study evaluated the antihypertensive efficacy and safety of nebivolol, a selective beta1-adrenoreceptor blocker with vasodilating effects, in patients with mild to moderate hypertension (sitting diastolic blood pressure [SiDBP] > or =95 mm Hg and < or =109 mm Hg). A total of 909 patients were randomized to receive placebo or nebivolol 1.25, 2.5, 5, 10, 20, or 40 mg once daily for up to 84 days. The primary end point was the change in trough SiDBP from baseline to study end. Nebivolol significantly reduced trough SiDBP (8.0-11.2 mm Hg compared with 2.9 mm Hg with placebo; P<.001) and trough sitting systolic blood pressure (a 4.4-9.5-mm Hg decrease compared with a 2.2-mm Hg increase [corrected] with placebo; P< or =.002). The overall adverse event experience was similar in the nebivolol (46.1%) and placebo (40.7%) groups (P=.273). Once-daily nebivolol ...

2007-09-01

11

Efficacy and safety of certolizumab pegol in an unselected crohn's disease population: 26-week data of the FACTS II survey  

British Library Electronic Table of Contents (United Kingdom)

AbstractBackground: Certolizumab pegol (Cimzia, CZP) was approved for the treatment of Crohn's disease (CD) patients in 2007 in Switzerland as the first country worldwide. This prospective phase IV study aimed to evaluate the efficacy and safety of CZP over 26 weeks in a multicenter cohort of practice-based patients. Methods: Evaluation questionnaires at baseline, week 6, and week 26 were completed by gastroenterologists in hospitals and private practices. Adverse events were evaluated according to World Health Organization (WHO) guidelines. Results: Sixty patients (38F/22M) were included; 53% had complicated disease (stricturing or penetrating), 45% had undergone prior CD-related surgery. All patients had prior exposure to systemic steroids, 96% to immunomodulators, 73% to infliximab, and...

2011-01-01

12

Zoledronate to Preserve Bone Mineral Density  

Science.gov (United States)

Phase II Randomized Study of the Effect of Zoledronate Versus Observation on Bone Mineral Density of the Lumbar Spine in Patients Undergoing Risk-Reducing Excision of Both Ovaries (GOG-0215). See the protocol summary.

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Novel therapies for resistant focal segmental glomerulosclerosis (FONT) phase II clinical trial: study design  

UK PubMed Central (United Kingdom)

BackgroundThe lack of adequate randomized clinical trials (RCT) has hindered identification of new therapies that are safe and effective for patients with primary focal segmental...Full Text Available

14

A viral vaccine encoding PSA induces antigen spreading to a common set of self proteins in prostate cancer patients  

UK PubMed Central (United Kingdom)

PurposeWe previously reported a randomized phase II clinical trial combining a poxvirus-based vaccine encoding PSA with radiotherapy in patients with localized prostate...Full Text Available

2010-08-01

15

Efficacy and tolerability of 0.5% timolol maleate ophthalmic gel-forming solution QD compared with 0.5% levobunolol hydrochloride BID in patients with open-angle glaucoma or ocular hypertension.  

Science.gov (United States)

We compared the efficacy of timolol maleate ophthalmic gel-forming solution 0.5% QD with that of levobunolol hydrochloride 0.5% BID, as measured by change in intraocular pressure (IOP), effect on heart rate, and ocular tolerability. The study had a positive-controlled, double-masked, randomized, multicenter, 12-week, two-period (6 weeks each), crossover design. One hundred fifty-two patients with open-angle glaucoma or ocular hypertension were randomized to receive either timolol maleate gel-forming solution QD or levobunolol BID for 6 weeks, followed by a crossover to the alternate treatment. IOP and heart rate were measured at morning trough and peak during weeks 3, 6, 9, and 12. Timolol maleate gel-forming solution QD was comparable to levobunolol BID in reducing IOP at peak and trough. Although the effects on peak heart rate were similar between the two medications, the effect on trough heart rate of timolol maleate ...

16

Linearization effect in multifractal analysis: Insights from Random Energy Model analysis  

CERN Document Server

The analysis of the linearization effect in multifractal analysis, and hence of the estimation of moments for multifractal processes, is revisited borrowing concepts from the statistical physics of disordered systems, notably from the analysis of the so-called Random Energy Model. Considering a standard multifractal process (compound Poisson motion), chosen as a simple representative example, we show: i) the existence of a critical order q* beyond which moments, though finite, cannot be estimated through empirical averages, irrespective of the sample size of the observation; ii) that multifractal exponents necessarily behave linearly in q, for q > q*. Tailoring the analysis conducted for the Random Energy Model to that of Compound Poisson motion, we provide explicative and quantitative predictions for the values of q* and for the slope controlling the linear behavior of the multifractal exponents. These quantities are ...

2010-01-01

17

Telavancin versus Standard Therapy for Treatment of Complicated Skin and Skin Structure Infections Caused by Gram-Positive Bacteria: FAST 2 Study  

UK PubMed Central (United Kingdom)

Telavancin is a bactericidal lipoglycopeptide with a multifunctional mechanism of action. We conducted a randomized, double blind, active-control phase II trial. Patients ≥18 years of age with...Full Text Available

2006-03-01

18

Analytical study on analysis methods of several random variables for seismic nonlinear responses of reactor buildings  

International Nuclear Information System (INIS)

In the case wherein nonlinear seismic response analyses are carried out, the response values vary due to the variations in materials and modeling. In this paper, nonlinear analyses of several random variables are carried out using: i. a conventional method; ii. a two-point estimation method (i. and ii. are simplified methods); and iii. Monte Carlo simulation (detailed method) to examine the variability of the response in the excessive nonlinear range for seismic responses of shear walls. The analyses are performed to a PWR-3 loop type reactor building which is one of the most typical reactor buildings in Japan. The variations are considered in specified compressive strength of concrete, concrete damping factor, shear wave velocity of soil and shapes of shear stress-strain relation curves of shear walls. As the results by the two simplified methods closely matched the Monte Carlo simulation results, the appropriateness for ...

1993-08-15

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Submucosal Dexamethasone Injection Improves Quality of Life Measures After Third Molar Surgery: A Comparative Study  

British Library Electronic Table of Contents (United Kingdom)

PurposeThe purpose of the present study was to compare the effect of submucosal versus intramuscular administration of dexamethasone sodium phosphate on patients' quality of life after surgical removal of impacted lower third molars. Patients and MethodsA randomized, non-blind, clinical trial was planned. The sample was composed of patients requiring extraction under local anesthesia of a single partial bony impacted mandibular third molar with Class II or III and position B or C, according to the Pell and Gregory classification. The patients were randomly distributed into 1 of 3 groups: submucosal dexamethasone, intramuscular dexamethasone, and a control group that received no steroid. A modified translated questionnaire was used to assess the patients' perception regarding different qual...

2011-01-01

20

On The Parent Population of Radio Galaxies and the FR I--II Dichotomy  

CERN Document Server

The possibility of radio galaxies being random sample of otherwise normal elliptical galaxies is tested. Starting with the observed optical luminosity functions for elliptical galaxies, it is shown that the probability of an elliptical forming a radio source is a continuous, increasing function of optical luminosity, precisely proportional to square of the optical luminosity of the galaxy. Once the probability function is fixed, the luminosity function of normal elliptical galaxies is used as input for Monte Carlo simulations that reproduce the distribution of radio galaxies in the radio-optical luminosity plane. Our results show that radio galaxies are luminosity biased, but otherwise random sample of elliptical galaxies. This unified view of radio and non-radio ellipticals also explains the well known difference of 0.5 mag in average optical luminosity between FRI and FRII radio galaxies as a simple selection effect. Specifically, FRII appear ...

2001-01-01

21

Should fresh blood be recommended for intensive care patients?  

UK PubMed Central (United Kingdom)

Fresh blood has many potential advantages over older blood, but there is no evidence that these properties translate into clinical benefit for intensive care patients. The observational multicenter...Full Text Available

2010-01-01

22

Prevalence of Ocular Fundus Pathology in Patients with Chronic Kidney Disease  

UK PubMed Central (United Kingdom)

Background and objectives: The objective of this study was to describe the prevalence of ocular fundus pathology in the Chronic Renal Insufficiency Cohort (CRIC) study, a multicenter, longitudinal study...Full Text Available

2010-05-01

23

Multicenter EuroTravNet/GeoSentinel Study of Travel-related Infectious Diseases in Europe  

UK PubMed Central (United Kingdom)

We analyzed prospective data on 17,228 European patients who sought treatment at GeoSentinel sites from 1997 to 2007. Gastrointestinal illness (particularly in tourists), fever (those visiting friends...Full Text Available

2009-11-01

24

Multicenter Case-Control Study on Restless Legs Syndrome in Multiple Sclerosis: the REMS Study  

UK PubMed Central (United Kingdom)

Study objectives:To verify the existence of a symptomatic form of restless legs syndrome (RLS) secondary to multiple sclerosis (MS) and to identify possible associated risk factors.Design:Prospective,...Full Text Available

2008-07-01

25

Double-blind trial of the efficacy of pentoxifylline vs thalidomide for the treatment of type II reaction in leprosy  

Scientific Electronic Library Online (English)

Abstract in english Type II reaction in leprosy, or erythema nodosum leprosum (ENL), is often characterized by severe clinical symptoms together with nerve function impairment leading to permanent disabilities. Thalidomide has been shown to be a highly effective drug for the treatment of ENL. It is, however, contraindicated for women of childbearing age due to its teratogenicity. On the other hand, pentoxifylline, used to treat hypercoagulable states, is not teratogenic and, like thalidomide (more) , can inhibit the synthesis of tumor necrosis factor-a and other cytokines. In the present randomized double-blind clinical study we compared the effectiveness of orally administered pentoxifylline vs thalidomide in treating type II reaction in 44 patients. Daily doses of 300 mg thalidomide or 1.2 g pentoxifylline were administered for 30 days to multibacillary leprosy patients undergoing type II reaction. ...

2007-02-01

26

Randomized Algorithms for Analysis and Control of Uncertain Systems  

CERN Document Server

Randomized Algorithms for Analysis and Control of Uncertain Systems

2005-01-01

27

The effectiveness of glucose, sucrose, and fructose in treating hypoglycemia in children with type 1 diabetes  

British Library Electronic Table of Contents (United Kingdom)

Husband AC, Crawford S, McCoy LA, Pacaud D. The effectiveness of glucose, sucrose, and fructose in treating hypoglycemia in children with type 1 diabetes. Objective: There is a lack of evidence regarding the most effective treatment option for managing naturally occurring hypoglycemia in children with type 1 diabetes. The objectives of this study were (i) to determine if sucrose and fructose are equally effective as glucose in the treatment of spontaneous hypoglycemia in children with type 1 diabetes; and (ii) to determine prestudy and poststudy hypoglycemia treatment preferences. Methods: Thirty-three subjects [aged 5.4-15.5 yr and average duration of type 1 diabetes of 3.1 yr (SD = 2.3)] participated in a randomized, crossover design. The main outcome was the effectiveness of treatment a...

2010-01-01

28

Cost-effectiveness of a barrier-strengthening moisturizing cream as maintenance therapy vs. no treatment after an initial steroid course in patients with atopic dermatitis in Sweden - with model applications for Denmark, Norway and Finland  

British Library Electronic Table of Contents (United Kingdom)

Abstract Background Atopic dermatitis (AD) affects health and quality of life and it has great impact on both health-care costs and costs to the society. Objectives The objective of this study was to develop a model to analyse the cost-effectiveness of a barrier-strengthening moisturizing cream as maintenance therapy compared with no treatment after initial treatment with betamethasone valerate in adult patients with AD in Sweden. A further aim was to apply a similar health-economic analysis for Denmark, Norway and Finland. Methods A Markov simulation model was developed including data from three sources: (i) efficacy data from a randomized controlled trial including patients with moderate AD treated with either a moisturizing cream or no treatment, (ii) resource utilization and quality of...

2010-01-01

29

Associations between a highly invasive species and native macrophytes differ across spatial scales  

British Library Electronic Table of Contents (United Kingdom)

The association between invasive and native species varies across spatial scales and is affected by phylogenetic relatedness, but these issues have rarely been addressed in aquatic ecosystems. In this study, we used a non-native, highly invasive species of Poaceae (tropical signalgrass) to test the hypotheses that (i) tropical signalgrass success correlates negatively with success of most native species of macrophytes at fine spatial scales, but its success correlates positively or at random with natives at coarse spatial scales, and that (ii) tropical signalgrass is less associated with native species belonging to the family Poaceae than with species belonging to other families (Darwin?s naturalization hypothesis). We used a dataset obtained at fine (0.25?m2) and coarse (ca. 1,000?m2) sca...

2011-01-01

32

Non-seminomatous testicular germ cell tumours. Preliminary analysis of ongoing trials in the DATECA study  

Energy Technology Data Exchange (ETDEWEB)

This report deals with the preliminary results of trials in the DATECA project with stage I, II and III patients with non-seminomatous germ cell tumours. Stage 1 patients were randomized between infradiaphragmatic irradiation and observation. No significant difference in recurrence rates has been observed as yet. Eighteen of 95 patients had recurrence with a median time to relapse of 3 months. Fifteen patients achieved complete remission after treatment by combination chemotherapy while 3 patients are still undergoing treatment. Stage II patients received 6 series of cis-platinum, bleomycin, and vinblastine. The patients were initially randomized to receive chemotherapy alone versus chemotherapy plus irradiation. Irradiation led to increased toxicity and decreased doses of the antineoplastic drugs. Fifty-one patients were studied. The overall complete remission rate was 89 per cent including 7 patients ...

1984-01-01

33

Non-seminomatous testicular germ cell tumours  

International Nuclear Information System (INIS)

This report deals with the preliminary results of trials in the DATECA project with stage I, II and III patients with non-seminomatous germ cell tumours. Stage 1 patients were randomized between infradiaphragmatic irradiation and observation. No significant difference in recurrence rates has been observed as yet. Eighteen of 95 patients had recurrence with a median time to relapse of 3 months. Fifteen patients achieved complete remission after treatment by combiantion chemotherapy while 3 patients are still undergoing treatment. Stage II patients received 6 series of cis-platinum, bleomycin, and vinblastine. The patients were initially randomized to receive chemotherapy alone versus chemotherapy plus irradiation. Irradiation led to increased toxicity and decreased doses of the antineoplastic drugs. Fifty-one patients were studied. The overall complete remission rate was 89 per cent including 7 patients ...

1984-01-01

34

The MonoPrep Pap test for the detection of cervical cancer and its precursors. Part I: results of a multicenter clinical trial.  

Science.gov (United States)

The MonoPrep Pap Test (MPPT; MonoGen, Lincolnshire, IL) is a novel, liquid-based specimen collection and processing technology for cytologic and molecular testing. Its usefulness in the detection of cervical cancer and its precursors was evaluated in a multicenter, masked, adjudicated, split-sample study of 10,739 samples. After preparation of a conventional smear, the residuum on the collection device was rinsed into a collection vial from which an MPPT slide was prepared. Accuracy was assessed by masked reference interpretation by an independent pathologist. Slides prepared by MPPT, compared with smears, yielded statistically significant increases in relative sensitivity for atypical squamous cells of undetermined significance and worse, atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion/atypical glandular cells and worse, and low-grade squamous intraepithelial lesion and worse. There was no significant difference in relative ...

2008-02-01

35

Structural, electronic and energetic properties of silicon carbon alloys  

International Nuclear Information System (INIS)

We studied the influence of alloying on the structural and electronic properties of the unrelaxed and relaxed Si_1_-_yC_y random alloys by means of ab initio theoretical calculations using two methods: (i) a supercell approach in connection with the plane-wave pseudopotential method; (ii) the full-potential augmented plane-wave plus local orbitals (APW+lo) method. The first method is used to obtain the relaxed atomic structure. The relaxed atomic positions obtained by pseudopotential calculations were used to calculate the band structure via the second method. The local density approximation was used for the exchange and correlation energy density functional. We investigated the lattice parameters and band gap energies. We found that a quite smaller gap appears in the neighborhood of y=0.03125 concentration of C atoms. The band gap shows a large anomalous bowing and is strongly composition dependent. The electron densities of states for the ...

2007-01-15

36

Precipitation during controlled cooling of magnesia-partially-stabilized zirconia  

Energy Technology Data Exchange (ETDEWEB)

A study has been made of the precipitation and growth processes which occur during cooling from solution treatment and under isothermal hold conditions in a magnesia-partially-stabilized zirconia alloy. Three types of precipitate have been identified which develop during cooling or during isothermal hold treatments just above and below the eutectoid temperature. These precipitate forms are termed (i) primary, (ii) large random, and (iii) secondary. Further precipitation, slow growth of existing precipitates, and subeutectoid decomposition result when an additional 1100/sup 0/C aging treatment is given to the previously cooled material. It is shown that type (iii) secondary precipitates from rapidly within the temperature range of 1300/sup 0/ to 1375/sup 0/C. The secondary precipitates are largely responsible for the improved room-temperature strength properties of the heat-treated samples. The formation and effects on mechanical properties of ...

1986-07-01

37

Precipitation during controlled cooling of magnesia-partially-stabilized zirconia  

International Nuclear Information System (INIS)

A study has been made of the precipitation and growth processes which occur during cooling from solution treatment and under isothermal hold conditions in a magnesia-partially-stabilized zirconia alloy. Three types of precipitate have been identified which develop during cooling or during isothermal hold treatments just above and below the eutectoid temperature. These precipitate forms are termed (i) primary, (ii) large random, and (iii) secondary. Further precipitation, slow growth of existing precipitates, and subeutectoid decomposition result when an additional 1100"0C aging treatment is given to the previously cooled material. It is shown that type (iii) secondary precipitates from rapidly within the temperature range of 1300"0 to 1375"0C. The secondary precipitates are largely responsible for the improved room-temperature strength properties of the heat-treated samples. The formation and effects on mechanical properties of each type of ...

38

GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries  

UK PubMed Central (United Kingdom)

There are many methods for introducing random mutations into nucleic acid sequences. Previously, we described a suite of programmes for estimating the completeness and diversity of randomized DNA libraries...Full Text Available

2008-07-01

39

X11 Desktop Environments (KDE and GNOME) - Part II  

CERN Document Server

X11 Desktop Environments (KDE and GNOME) - Part II

2000-01-01

40

Java-based Graphical User Interface for MAVERIC-II  

Science.gov (United States)

A computer program entitled "Marshall Aerospace Vehicle Representation in C II,

2005-01-01

41

Molecular targeted treatment and radiation therapy for rectal cancer  

Energy Technology Data Exchange (ETDEWEB)

Background: EGFR (epidermal growth factor receptor) and VEGF (vascular endothelial growth factor) inhibitors confer clinical benefit in metastatic colorectal cancer when combined with chemotherapy. An emerging strategy to improve outcomes in rectal cancer is to integrate biologically active, targeted agents as triple therapy into chemoradiation protocols. Material and methods: cetuximab and bevacizumab have now been incorporated into phase I-II studies of preoperative chemoradiation therapy (CRT) for rectal cancer. The rationale of these combinations, early efficacy and toxicity data, and possible molecular predictors for tumor response are reviewed. Computerized bibliographic searches of Pubmed were supplemented with hand searches of reference lists and abstracts of ASCO and ASTRO meetings. Results: the combination of cetuximab and CRT can be safely applied without dose compromises of the respective treatment components. Disappointingly low rates of pathologic ...

2009-06-15

42

Synthesis and characterization of nickel(II), chromium(III), cobalt(II), copper(II), zinc(II), and cadmium(II) complexes with isatin- isonicotinoylhydrazone  

International Nuclear Information System (INIS)

A few metal complexes of isatin-isonicotinoylhydrazone with Ni(II), Cr(III), Co(II), Cu(II), Zn(II) and Cd(II) have been prepared and characterized on the basis of elemental analyses, infrared and electronic spectra as well as "1H NMR spectra, conductivity and magnetic measurements. In view of the results obtained, it has been found that two molecules of isatin-isonicotinoylhydrazone are chelated to the central metal ion as bis-uninegative ONO tridentate ligand forming non-electrolytic octahedral metal complexes. (author)

1997-03-01

46

Choice and meaning in the quantum universe  

Energy Technology Data Exchange (ETDEWEB)

This report discusses whether the events that occur in the universe evolve deterministicly or randomly or both. (LSP).

1992-05-22

47

Extremal behavior of a coupled continuous time random walk  

British Library Electronic Table of Contents (United Kingdom)

Coupled continuous time random walks (CTRWs) model normal and anomalous diffusion of random walkers by taking the sum of random jump lengths dependent on the random waiting times immediately preceding each jump. They are used to simulate diffusion-like processes in econophysics such as stock market fluctuations, where jumps represent financial market microstructure like log returns. In this and many other applications, the magnitude of the largest observations (e.g. a stock market crash) is of considerable importance in quantifying risk. We use a stochastic process called a coupled continuous time random maxima (CTRM) to determine the density governing the maximum jump length of a particle undergoing a CTRW. CTRM are similar to continuous time random walks but track maxima instead of sums....

2011-01-01

48

Quenched large deviations for random walk in a random environment  

CERN Document Server

We take the point of view of a particle performing random walk with bounded jumps on Z^d in a stationary and ergodic random environment. We prove the quenched large deviation principle (LDP) for the pair empirical measure of the environment Markov chain. By the contraction principle, we deduce the quenched LDP for the mean velocity of the particle and obtain a variational formula for the corresponding rate function. We propose an Ansatz for the minimizer of this formula. We verify this Ansatz for nearest-neighbor walks on Z. As a separate result, we give a probabilistic formula for the ergodic invariant density of the environment Markov chain in the case of ballistic random walk with bounded jumps on Z.

2008-01-01

51

Catalytic hydration of alkynes with platinum(II) complexes  

Energy Technology Data Exchange (ETDEWEB)

Platinum(II) complexes have been investigated in the hydration of alkynes. These catalysts offer improved regioselectivity over Hg(II) counterparts. 1 fig., 2 tabs.

1993-12-17

52

Effect of D-amino acids at Asp"2"3 and Ser"2"6 residues on the conformational preference of A#beta#_2_0_-_2_9 peptides  

International Nuclear Information System (INIS)

The effects of D-amino acids at Asp"2"3 and Ser"2"6 residues on the conformational preference of #beta#-amyloid (A#beta#) peptide fragment (A#beta#_2_0_-_2_9) have been studied using different spectroscopic techniques, namely vibrational circular dichroism (VCD), vibrational absorption, and electronic circular dichroism. To study the structure of the A#beta#_2_0_-_2_9, [D-Asp"2"3]A#beta#_2_0_-_2_9, and [D-Ser"2"6]A#beta#_2_0_-_2_9 peptides under different conditions, the spectra were measured in 10 mM acetate buffer (pH 3) and in 2,2,2-trifluoroethanol (TFE). The spectroscopic results indicated that at pH 3, A#beta#_2_0_-_2_9 peptide takes random coil with #beta#-turn structure, while [D-Ser"2"6]A#beta#_2_0_-_2_9 peptide adopts significant amount of polyproline II (PPII) type structure along with #beta#-turn contribution and D-Asp-substituted peptide ([D-Asp"2"3]A#beta#_2_0_-_2_9) adopts predominantly PPII type structure. The increased ...

2005-09-30

55

The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias  

UK PubMed Central (United Kingdom)

BackgroundInterim analysis of accumulating trial data is important to protect participant safety during randomized controlled trials (RCTs). Data Monitoring Committees (DMCs) often...Full Text Available

56

Stopping or Reporting Early for Positive Results in Randomized Clinical Trials: The National Cancer Institute Cooperative Group Experience From 1990 to 2005  

UK PubMed Central (United Kingdom)

Randomized clinical trials are designed with stopping boundaries to guide data monitoring committees with their decision making concerning ongoing trials. In particular, when extremely positive results...Full Text Available

2009-04-01

57

Randomized Controlled Trials of Interventions to Prevent Sexually Transmitted Infections: Learning From the Past to Plan for the Future  

UK PubMed Central (United Kingdom)

Globally, sexually transmitted infections (STIs) represent a significant source of morbidity and disproportionately impact the health of women and children. The number of randomized controlled trials...Full Text Available

2010-04-01

58

Quality assessment of reporting of randomization, allocation concealment, and blinding in traditional chinese medicine RCTs: A review of 3159 RCTs identified from 260 systematic reviews  

UK PubMed Central (United Kingdom)

BackgroundRandomized controlled trials (RCTs) which are of poor quality tend to exaggerate the effect estimate and lead to wrong or misleading conclusions. The aim of this study...Full Text Available

59

Protein Coding Sequence Identification by Simultaneously Characterizing the Periodic and Random Features of DNA Sequences  

UK PubMed Central (United Kingdom)

Most codon indices used today are based on highly biased nonrandom usage of codons in coding regions. The background of a coding or noncoding DNA sequence, however, is fairly random, and can be characterized...Full Text Available

2005-01-01

60

Identification of genes and haplotypes that predict rheumatoid arthritis using random forests  

UK PubMed Central (United Kingdom)

Random forest (RF) analysis of genetic data does not require specification of the mode of inheritance, and provides measures of variable importance that incorporate interaction effects. In this paper...Full Text Available

61

Evidence for nonrandom hydrophobicity structures in protein chains.  

UK PubMed Central (United Kingdom)

The question of whether proteins originate from random sequences of amino acids is addressed. A statistical analysis is performed in terms of blocked and random walk values formed by binary hydrophobic...Full Text Available

1996-09-03

62

Comparison of deferral rates using a computerized versus written blood donor questionnaire: a randomized, cross-over study [ISRCTN84429599  

UK PubMed Central (United Kingdom)

BackgroundSelf-administered computer-assisted blood donor screening strategies may elicit more accurate responses and improve the screening process.MethodsRandomized...Full Text Available

63

Biotin binders selected from a random peptide library expressed on phage.  

UK PubMed Central (United Kingdom)

Recombinant biotin-binding phages were affinity-selected from a random peptide library expressed on the surface of filamentous phage. Phage binding to biotinylated proteins was half-maximally inhibited...Full Text Available

1993-08-01

64

Binary Pseudo-Random Gratings and Arrays for Calibration of Modulation Transfer Function of Surface Profilometers  

Energy Technology Data Exchange (ETDEWEB)

In the present work, we describe application of binary pseudo-random gratings (BPRG) and arrays (BPRA) as effective 1D and 2D test surfaces suitable for calibration of different surface profilometers, including a number of interferometric microscopes and scatterometers.

2009-06-17

65

Adverse events associated with acupuncture: three multicentre randomized controlled trials of 1968 cases in China  

UK PubMed Central (United Kingdom)

BackgroundIn order to evaluate the safety of acupuncture in China objectively, we investigated the adverse events associated with acupuncture based on three multicentre randomized...Full Text Available

66

The Analytic Methods of Operations Research  

Science.gov (United States)

... of the utility of the terminal outcomes, ... Other stochastic topics, such as random walks, branching ... find special uses, particularly in queueing theory ...

1977-01-01

67

THE APPLICATION OF STATISTICS TO THE FLIGHT ...  

Science.gov (United States)

... Measuring Instruments ..... 7-18 7.4 Power Spectral Density Measurements of Random DaL. .... 7-19 7 ...

1961-12-01

68

Sharp asymptotics for metastability in the random field Curie-Weiss model  

CERN Document Server

In this paper we study the metastable behavior of one of the simplest disordered spin system, the random field Curie-Weiss model. We will show how the potential theoretic approach can be used to prove sharp estimates on capacities and metastable exit times also in the case when the distribution of the random field is continuous. Previous work was restricted to the case when the random field takes only finitely many values, which allowed the reduction to a finite dimensional problem using lumping techniques. Here we produce the first genuine sharp estimates in a context where entropy is important.

2008-01-01

69

Randomization of heavily damaged regions in annealed low energy Ge{sup +}-implanted (0 0 1)Si  

Energy Technology Data Exchange (ETDEWEB)

Apparent growth of amorphous layers during low temperature annealing was observed in low energy Ge{sup +}-implanted (0 0 1)Si by high-resolution transmission electron microscopy. The occurrence of abnormal growth is due to the randomization of heavily damaged regions beneath the original amorphous/crystalline interfaces. The randomization process is attributed to the strain, incurred by the presence of a high density of large Ge atoms in the heavily damaged Si substrate, relaxation to lower the free energy of the systems. The randomization upon annealing may be fruitfully applied to minimize the transient enhanced diffusion in shallow junction formation.

2004-01-15

70

Randomization of heavily damaged regions in annealed low energy Ge"+-implanted (0 0 1)Si  

International Nuclear Information System (INIS)

Apparent growth of amorphous layers during low temperature annealing was observed in low energy Ge"+-implanted (0 0 1)Si by high-resolution transmission electron microscopy. The occurrence of abnormal growth is due to the randomization of heavily damaged regions beneath the original amorphous/crystalline interfaces. The randomization process is attributed to the strain, incurred by the presence of a high density of large Ge atoms in the heavily damaged Si substrate, relaxation to lower the free energy of the systems. The randomization upon annealing may be fruitfully applied to minimize the transient enhanced diffusion in shallow junction formation.

2004-01-01

71

Local central limit theorems in stochastic geometry  

CERN Document Server

We give a general local central limit theorem for the sum of two independent random variables, one of which satisfies a central limit theorem while the other satisfies a local central limit theorem with the same order variance. We apply this result to various quantities arising in stochastic geometry, including: size of the largest component for percolation on a box; number of components, number of edges, or number of isolated points, for random geometric graphs; covered volume for germ-grain coverage models; number of accepted points for finite-input random sequential adsorption; sum of nearest-neighbour distances for a random sample from a continuous multidimensional distribution.

2010-01-01

72

A Simulation Model for Estimating Airport Terminal Area ...  

Science.gov (United States)

... AIR TRAFFIC, TERMINAL FLIGHT ... FLIGHT, RANDOM VARIABLES, STOCHASTIC PROCESSES ... COMPUTER PROGRAMS, QUEUEING THEORY. ...

1971-05-01

74

The Protective Effect of Antioxidants on Oxidative Stress in Rats Exposed to the 950 MHz Electromagnetic Field  

International Nuclear Information System (INIS)

Studies have linked cell phone radiation to health problems such as headaches, high blood pressure, cancer and more. There is a latency period for most diseases and it may take years and more studies before the required weight of evidence is established. But the effects are cumulative and precautions should be taken now before it is too late. The aim of the present study was to investigate if supplementation with antioxidants would protect heart and liver tissues from harmful radiation emitted by cell phone. Thirty two male albino rats were randomly divided into four equal groups: I- Control, II- Antioxidants treated group, III- 950 MHz EMR, IV- 950 MHz EMR + antioxidants. A 950 MHz EMR radiation (217-Hz pulse rate, 2-W maximum peak power, SAR Specific Absorption Rate"1.6 W/Kg) was applied to groups III and IV 60 min/day, for 30 days using an experimental exposure device. Antioxidants supplement (Vitamins A, E and C + Se) was administered to ...

75

Receptor model applied to patterns in space (RMAPS). Part II - apportionment of airborne particulate sulfur from project MOHAVE  

Energy Technology Data Exchange (ETDEWEB)

Airborne fine particle sulfur data from the summer intensive of Project MOHAVE (Measurement of Haze and Visual Effects) was analyzed by the Receptor Model Applied to Patterns in Space (RMAPS) model, a novel multivariate receptor-oriented model that applies to secondary and primary species. The sulfur data from 17 sites were found to be well predicted by three spatial patterns interpreted as sources along the valley of the Colorado River (including the large Mohave coal-fired power plant, a smaller power plant and the city of Las Vegas); transport from sources located to the southwest; and transport from sources located to the southeast. The model was tested by using parameters derived from the 17-site data set to apportion sulfur for six sites that were not part of the original data set. The sulfur apportionment for these site sites was in agreement with the original apportionment and the physical interpretation of the spatial patterns given above. The effects of systematic and ...

1997-02-01

76

Radon measurements in soil - tests in Krakow agglomeration  

International Nuclear Information System (INIS)

The migration of gaseous radon through the soil is depending on the geology of the region and may vary locally because of occurrence of fractures in impermeable layers and existence of fractures and faults. To identify areas with elevated radon concentration in soil gas, it is very helpful to know the geological structure of the area under study and how the high permeability soils are situated in the overburden. Topography of the surface in the Krakow area is determined by exhumed structure of late Alpine foreland, dismembered into systems of several normal fault-bounded carbonate horsts, erosional monadocks and grabens, and partially filled with marine Miocene clays of Carpathian foredeep basin. Radon geofluid, generated partially in sub-Jurassic, U-rich crystalline basement, migrates vertically to surface through permeable, jointed, faulted and karstified Jurassic limestone. Under the cover the radon fluxes are channelled by adjacent list ric faults and clay/limestone interfaces ...

2000-10-14

77

Observation of B0(s) - anti-B0(s) Oscillations  

Energy Technology Data Exchange (ETDEWEB)

The authors report the observation of B{sub s}{sup 0}-{bar B}{sub s}{sup 0} oscillations from a time-dependent measurement of the B{sub s}{sup 0}-{bar B}{sub s}{sup 0} oscillation frequency {Delta}m{sub s}. Using a data sample of 1 fb{sup -1} of p{bar p} collisions at {radical}s = 1.96 TeV collected with the CDF II detector at the Fermilab Tevatron, they find signals of 5600 fully reconstructed hadronic B{sub s} decays, 3100 partially reconstructed hadronic B{sub s} decays, and 61,500 partially reconstructed semileptonic B{sub s} decays. They measure the probability as a function of proper decay time that the B{sub s} decays with the same, or opposite, flavor as the flavor at production, and they find a signal for B{sub s}{sup 0}-{bar B}{sub s}{sup 0} oscillations. The probability that random fluctuations could produce a comparable signal is 8 x 10{sup -8}, which exceeds 5{sigma} significance. They measure {Delta}m{sub s} = 17.77 {+-} ...

2006-09-01

78

Formation of silk fibroin nanoparticles in water-miscible organic solvent and their characterization  

Energy Technology Data Exchange (ETDEWEB)

When Silk fibre derived from Bombyx mori, a native biopolymer, was dissolved in highly concentrated neutral salts such as CaCl{sub 2}, the regenerated liquid silk, a gradually degraded peptide mixture of silk fibroin, could be obtained. The silk fibroin nanoparticles were prepared rapidly from the liquid silk by using water-miscible protonic and polar aprotonic organic solvents. The nanoparticles are insoluble but well dispersed and stable in aqueous solution and are globular particles with a range of 35-125 nm in diameter by means of TEM, SEM, AFM and laser sizer. Over one half of the {epsilon}-amino groups exist around the protein nanoparticles by using a trinitrobenzenesulfonic acid (TNBS) method. Raman spectra shows the tyrosine residues on the surface of the globules are more exposed than those on native silk fibers. The crystalline polymorph and conformation transition of the silk nanoparticles from random-coil and {alpha}-helix form (Silk I) into ...

2007-10-15

79

Contribution of first-principles energetics to the Ca-Mg thermodynamic modeling  

International Nuclear Information System (INIS)

The first-principles energetics of the constituent elements Ca and Mg and the Mg_2Ca C14 laves phase (C14) in the Ca-Mg binary system were used in the computational thermodynamic modeling, with models for the Gibbs energy of individual phases. C14 was modeled as (Ca,Mg)_2(Ca,Mg)_1 with four end-members. The first-principles calculations were performed using two computer codes: (i) WIEN2K based on the full-potential linearized augmented plane-wave (FLAPW) method and (ii) VASP based on the pseudo-potentials and a plane wave basis set. The total energies of the pure Ca and Mg in the fcc, bcc, and hcp structures, three laves phase structures of Mg_2Ca, and the four end-members of C14 were calculated at 0 K. The enthalpies of formation of the four end-members were obtained accordingly and used as input data in evaluating the Gibbs energy functions of C14. The entropy contribution in the Gibbs energy function for C14 was obtained through its liquidus data. Special ...

2006-08-31

80

Concurrent and adjuvant docetaxel with three-dimensional conformal radiation therapy plus androgen deprivation for high-risk prostate cancer: Preliminary results of a multicentre phase II trial  

International Nuclear Information System (INIS)

Background and purpose: We evaluate the feasibility of concomitant and adjuvant docetaxel combined with three-dimensional conformal radiotherapy (3D-CRT) and androgen deprivation in high-risk prostate carcinomas. Methods: Fifty men with high-risk localized prostate cancer (16), locally advanced (28) or very high-risk prostate cancer (6) were included. Seventy Gy were delivered on prostate and seminal vesicles in 35 fractions, concurrently with weekly docetaxel (20 mg/m"2). Three weeks after the completion of 3D-CRT, docetaxel was given for 3 cycles (60 mg/m"2), every 3 weeks. Patients had to receive LHRH agonist during 3 years. Results: The intent to treat analysis shows that four patients out of 15 stopped prematurely the chemotherapy due to grade 3-4 acute toxicity. In the per protocol analysis, 46 patients completed a full-dose chemoradiation regimen representing 413 cycles: five patients experienced a grade 3 toxicity, and 15 patients experienced a grade 2 toxicity. With a median ...

2010-11-01

81

Results for the structural properties of random heaps of hard disks  

Energy Technology Data Exchange (ETDEWEB)

The average angle of repose and the packing density of random planar heaps of hard disks falling ballistically onto a sticky base line, where the first layer of disks is quenched in random positions, are computed for heaps with a small fixed number of gaps in the base layer. The results we find appear to be almost independent of the size of the heap and they agree with those obtained from computer simulations of large systems.

1995-01-01

82

Moderate deviations for stationary sequences of Hilbert valued bounded random variables  

CERN Document Server

In this paper, we derive the moderate deviation principle for stationary sequences of bounded random variables with values in a Hilbert space. The conditions obtained are expressed in terms of martingale-type conditions. The main tools are martingale approximations and a new Hoeffding inequality for non adpated sequences of Hilbert-valued random variables. Applications to Cramer-Von Mises statistics, functions of linear processes and stable Markov chains are given.

2008-01-01

83

Dimers and orthogonal polynomials: connections with random matrices  

CERN Document Server

In these lecture notes we present some connections between random matrices, the asymmetric exclusion process, random tilings. These three apparently unrelated objects have (sometimes) a similar mathematical structure, an interlacing structure, and the correlation functions are given in terms of a kernel. In the basic examples, the kernel is expressed in terms of orthogonal polynomials.

2010-01-01

84

A SAS macro for a clustered logrank test  

British Library Electronic Table of Contents (United Kingdom)

Abstract: The clustered logrank test is a nonparametric method of significance testing for correlated survival data. Examples of its application include cluster randomized trials where groups of patients rather than individuals are randomized to either a treatment or a control intervention. We describe a SAS macro that implements the 2-sample clustered logrank test for data where the entire cluster is randomized to the same treatment group. We discuss the theory and applications behind this test as well as details of the SAS code.

2011-01-01

85

Automatic segmentation of thoracic and pelvic CT images for radiotherapy planning using implicit anatomic knowledge and organ-specific segmentation strategies  

Energy Technology Data Exchange (ETDEWEB)

Automatic segmentation of anatomical structures in medical images is a valuable tool for efficient computer-aided radiotherapy and surgery planning and an enabling technology for dynamic adaptive radiotherapy. This paper presents the design, algorithms and validation of new software for the automatic segmentation of CT images used for radiotherapy treatment planning. A coarse to fine approach is followed that consists of presegmentation, anatomic orientation and structure segmentation. No user input or a priori information about the image content is required. In presegmentation, the body outline, the bones and lung equivalent tissue are detected. Anatomic orientation recognizes the patient's position, orientation and gender and creates an elastic mapping of the slice positions to a reference scale. Structure segmentation is divided into localization, outlining and refinement, performed by procedures with implicit anatomic knowledge using standard image processing operations. ...

2008-03-21

86

JMassBalance: mass-balanced randomization and analysis of metabolic networks  

British Library Electronic Table of Contents (United Kingdom)

Summary: Analysis of biological networks requires assessing the statistical significance of network-based predictions by using a realistic null model. However, the existing network null model, switch randomization, is unsuitable for metabolic networks, as it does not include physical constraints and generates unrealistic reactions. We present JMassBalance, a tool for mass-balanced randomization and analysis of metabolic networks. The tool allows efficient generation of large sets of randomized networks under the physical constraint of mass balance. In addition, various structural properties of the original and randomized networks can be calculated, facilitating the identification of the salient properties of metabolic networks with a biologically meaningful null model. Availability and Imp...

2011-01-01

87

Synthesis, characterization and biological evaluation of mononuclear Co(II), Ni(II), Cu(II) and Pd(II) complexes with new N2O2 Schiff base ligands.  

Science.gov (United States)

New tetradentate N(2)O(2) donor Schiff bases and their mononuclear Co(II), Ni(II), Cu(II), and Pd(II) complexes were synthesized and characterized extensively by IR, (1)H-, (13)C-NMR, mass, ESR, conductivity measurements, elemental and thermal analysis. Specifically the magnetic and electronic spectral measurements demonstrate the octahedral structures of cobalt(II), nickel(II) complexes and square planar geometries of copper(II), palladium(II) complexes. All the ligands and complexes were screened for their in vitro antibacterial activity against two gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus) and two gram-negative bacteria (Escherichia coli, Klebsiella pneumonia). In this study, Pd(II) complexes exhibited potent antibacterial activity against B. subtilis, S. aureus whereas ...

2011-02-01

88

Synthesis, Characterization and Biological Properties of Anions of Bivalent Transition Metal [Co(II) and Ni(II)] Complexes With Acylhydrazine Derived ONO Donor Schiff Bases  

UK PubMed Central (United Kingdom)

Some acylhydrazine derived ONO donor Schiff bases and their Co(II) and Ni(II) complexes have been prepared having the same metal ion (cation) but different anions. These synthesized metal(II)...Full Text Available

2000-01-01

89

The combination therapy with hepatic arterial infusion chemotherapy and radiation therapy for unresected intrahepatic cholangiocarcinoma  

International Nuclear Information System (INIS)

The outcome was retrospectively examined and prognostic factors were discussed for arterial chemo-infusion therapy (ACT) through an implanted reservoir system and radiation therapy (RT) in patients with unresectable intrahepatic cholangiocarcinoma (CCC). ACT plus RT were conducted to 25 patients (mean age 61.7 y, M/F 12/13, stage III-IVB) during 10 years from 1996 to 2005 with various regimens of cisplatin (CDDP), 5- fluorouracil (FU), epirubicin (FARM), mitomycin C (MMC) plus 39-50 Gy of radiation in a fractionated manner partly involving internal RT (2 cases, 15 Gy) and RT for metastatic bone (1, 25 Gy). The survival rates at 1, 2 and 3 years after ACT+RT were respectively 52.5, 43.7 and 28.1%; total efficacy (PR) was 36% (9/25) at 6 months; and significantly good prognostic factors were found to be female and absence of metastasis remote and/or lymphatic around artery. Authors concluded that ACT+RT was a meaningful treatment for highly advanced non-respectable CCC and that ...

2007-11-01

90

The SPIRIT V Study:A Clinical Evaluation of the XIENCE V Everolimus-Eluting Coronary Stent System in the Treatment of Patients With De Novo Coronary Artery Lesions  

British Library Electronic Table of Contents (United Kingdom)

ObjectivesThe SPIRIT V (A Clinical Evaluation of the XIENCE V Everolimus-Eluting Coronary Stent System in the Treatment of Patients With De Novo Coronary Artery Lesions) study is a post-market surveillance experience of the XIENCE V (Abbott Vascular, Santa Clara, California) everolimus-eluting stent (EES) in patients with higher-risk coronary anatomy. BackgroundPrevious pre-approval studies have shown the safety and efficacy of EES in highly selected groups of patients. MethodsThe SPIRIT V trial is a prospective, open label, single arm, multicenter study. Two thousand seven hundred patients with multiple de novo coronary artery lesions suitable for treatment with a planned maximum of 4 EES were enrolled at 93 centers in Europe, Asia Pacific, Canada, and South Africa. Lesions had a referenc...

2011-01-01

91

RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription  

UK PubMed Central (United Kingdom)

A structurally conserved element, the trigger loop, has been suggested to play a key role in substrate selection and catalysis of RNA polymerase II (pol II) transcription elongation. Recently resolved...Full Text Available

2010-09-07

92

PDP-1 Links the TGF-? and IIS Pathways to Regulate Longevity, Development, and Metabolism  

UK PubMed Central (United Kingdom)

The insulin/IGF-1 signaling (IIS) pathway is a conserved regulator of longevity, development, and metabolism. In Caenorhabditis elegans IIS involves activation of DAF-2 (insulin/IGF-1...Full Text Available

2011-04-01

93

Genetic heterogeneity in human T-cell leukemia/lymphoma virus type II.  

UK PubMed Central (United Kingdom)

DNA from the peripheral blood mononuclear cells of 17 different individuals infected with human T-cell lymphoma/leukemia virus type II (HTLV-II) was successfully amplified by the polymerase chain reaction...Full Text Available

1993-03-01

94

Type II Quantum Computing With Superconductors.  

Science.gov (United States)

The results of this research centered on the experimental studies of a single superconducting persistent current qubit, the implementation of type-II algorithms using these qubits, and the proposal for adiabatic quantum computing using these qubits. The m...

2004-01-01

96

Stress Tolerance of Photosystem II in Vivo  

UK PubMed Central (United Kingdom)

The in vivo photochemical activity of photosystem II was inferred from modulated chlorophyll fluorescence and photoacoustic measurements in intact leaves of several plant species (Lycopersicon...Full Text Available

1992-09-01

97

Radiation Damage Calculations for the FUBR and BEATRIX Irradiations of Lithium Compounds in EBR-II and FFTF  

Energy Technology Data Exchange (ETDEWEB)

Radiation Damage Calculations for the FUBR and BEATRIX Irradiations of Lithium Compunds in EBR-II and FFTF

1999-05-01

98

REDUCTION OF INORGANIC COMPOUNDS WITH MOLECULAR HYDROGEN BY MICROCOCCUS LACTILYTICUS II.  

UK PubMed Central (United Kingdom)

Woolfolk, C. A. (University of Washington, Seattle). Reduction of inorganic compounds with molecular hydrogen by Micrococcus lactilyticus. II. Stoichiometry with inorganic...Full Text Available

1962-10-01

99

Quantitative Spectroscopy of Photospheric-Phase Type II SN  

Science.gov (United States)

... and high-quality photospheric-phase Type II SN spectra to constrain core- collapse SN explosions, massive star evolution, and distances in the Universe ...

100

LLNL Compliance Plan for TRUPACT-2 Authorized Methods for Payload Control  

Energy Technology Data Exchange (ETDEWEB)

This document describes payload control at LLNL to ensure that all shipments of CH-TRU waste in the TRUPACT-II (Transuranic Package Transporter-II) meet the requirements of the TRUPACT-II SARP (safety report for packaging). This document also provides specific instructions for the selection of authorized payloads once individual payload containers are qualified for transport. The physical assembly of the qualified payload and operating procedures for the use of the TRUPACT-II, including loading and unloading operations, are described in HWM Procedure No. 204, based on the information in the TRUPACT-II SARP. The LLNL TRAMPAC, along with the TRUPACT-II operating procedures contained in HWM Procedure No. 204, meet the documentation needs for the use of the TRUPACT-II at LLNL. Table 14-1 provides a summary of the LLNL waste generation and ...

1995-03-01

101

Gravity Gradiometer Survey and Real Time Techniques for ...  

Science.gov (United States)

... 4 II. INERTIAL NAVIGATION ERROR EQUATIONS ..... 5 ... 4- Page 20. Chapter II INERTIAL NAVIGATION ERROR EQUATIONS ...

1981-12-01

102

Cd(II), Pb(II) and Zn(II) removal from contaminated water by biosorption using activated sludge biomass  

Energy Technology Data Exchange (ETDEWEB)

Biosorption using activated sludge biomass (ASB) as a potentially sustainable technology for the treatment of wastewater containing different metal ions (Cd(II), Pb(II) and Zn(II)) was investigated. ASB metal uptake clearly competed with protons consumed by microbial biomass compared with control tests with non-activated sludge biomass. Biosorption tests confirmed maximum exchange between metal ions and protons at pH 2.0-4.5. It was revealed by the study that the amount of metal ions released from the biomass increased with biomass sludge concentration. The result showed that maximum absorption of metal ions was observed for Cd(II) at pH 3.5, Pb(II) at pH 4.0, and pH 4.5 for Zn(II) ions. The maximum absorption capacities of ASB for Cd(II), Pb(II) and Zn(II) were determined to be 59.3, 68.5 and 86.5%, ...

2010-02-15

104

Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer  

DEFF Research Database (Denmark)

Purpose Cisplatin plus gemcitabine is a standard regimen for first-line treatment of advanced non-small-cell lung cancer (NSCLC). Phase II studies of pemetrexed plus platinum compounds have also shown activity in this setting. Patients and Methods This noninferiority, phase III, randomized study compared the overall survival between treatment arms using a fixed margin method (hazard ratio [HR] < 1.176) in 1,725 chemotherapy-naive patients with stage IIIB or IV NSCLC and an Eastern Cooperative Oncology Group performance status of 0 to 1. Patients received cisplatin 75 mg/m(2) on day 1 and gemcitabine 1,250 mg/m(2) on days 1 and 8 (n = 863) or cisplatin 75 mg/m(2) and pemetrexed 500 mg/m(2) on day 1 (n = 862) every 3 weeks for up to six cycles. Results Overall survival for cisplatin/pemetrexed was noninferior to cisplatin/ gemcitabine (median survival, 10.3 v 10.3 months, respectively; HR = 0.94; 95% CI, 0.84 to 1.05). Overall survival was ...

2008-01-01

105

Denaturation of Heterogeneous DNA  

CERN Document Server

The effect of pair-binding energy variations on the denaturation of double stranded DNAs is investigated. Using a two-parameter renormalization group (RG) analysis and extensive transfer matrix calculations, we find a random quenched-in variations to be marginally irrelevant, indicating that the system is self-averaging at the transition. The effect of a recently-proposed variable backbone stiffness is also investigated. Although irrelevant in the RG sense, it dramatically amplifies the randomness, leading to the appearance of ``multi-step melting'' for realistic sequences. These results are relevant to the adsorption of random heteropolymers and the wetting of disordered substrates.

1997-01-01

106

Vitamin D and Serum Cytokines in a Randomized Clinical Trial  

UK PubMed Central (United Kingdom)

Background. The role of vitamin D in the body's ability to fight influenza and URI's may be dependent on regulation of specific cytokines that participate in the host inflammatory...Full Text Available

2010-01-01

107

Uncorrelated Randomness of the Heart Rate Is Associated with Sepsis in Sick Premature Infants  

UK PubMed Central (United Kingdom)

BackgroundLate-onset sepsis in the premature infant is frequently revealed by severe, unusual and recurrent bradycardias. In view of the high morbidity and mortality...Full Text Available

2009-03-01

108

Syndromic management of urethral discharge in Ghanaian pharmacies  

UK PubMed Central (United Kingdom)

Objectives: To evaluate the training of pharmacists in Accra, Ghana, in the syndromic management of STIs. Methods: We randomly selected 50 pharmacy outlets that had...Full Text Available

2000-12-01

109

Sun Protection at Elementary Schools: A Cluster Randomized Trial  

UK PubMed Central (United Kingdom)

BackgroundElementary schools represent both a source of childhood sun exposure and a setting for educational interventions.MethodsSun Protection...Full Text Available

2010-04-07

110

Stochastic gene expression and its consequences  

UK PubMed Central (United Kingdom)

Gene expression is a fundamentally stochastic process, with randomness in transcription and translation leading to significant cell-to-cell variations in mRNA and protein levels. This variation...Full Text Available

2008-10-17

111

Prognostic Factors for Failure after Prostatectomy  

UK PubMed Central (United Kingdom)

Several randomized studies have been completed in prostate cancer that show a benefit to immediate postoperative treatment in patients undergoing prostatectomy. In one of the studies, there was even...Full Text Available

112

Prevalence of Cataract in an Older Population in India  

UK PubMed Central (United Kingdom)

PurposeTo describe the prevalence of cataract in older people in 2 areas of north and south India.DesignPopulation-based, cross-sectional study.ParticipantsRandomly...Full Text Available

2011-02-01

113

On the Impact of Longitudinal Breathing Motion Randomness for Tomotherapy Delivery  

UK PubMed Central (United Kingdom)

The purpose of this study is to explain the unplanned longitudinal dose modulations that appear in helical tomotherapy (HT) dose distributions in the presence of irregular patient breathing....Full Text Available

2008-09-21

114

Laparoscopic surgery for rectal cancer: The state of the art  

UK PubMed Central (United Kingdom)

At present time, there is evidence from randomized controlled studies of the success of laparoscopic resection for the treatment of colon cancer with reported smaller incisions, lower morbidity rate...Full Text Available

2010-09-27

115

Entropy and Hausdorff Dimension in Random Growing Trees  

CERN Document Server

We investigate the limiting behavior of random tree growth in preferential attachment models. The tree stems from a root, and we add vertices to the system one-by-one at random, according to a rule which depends on the degree distribution of the already existing tree. The so-called weight function, in terms of which the rule of attachment is formulated, is such that each vertex in the tree can have at most K children. We define the concept of a certain random measure mu on the leaves of the limiting tree, which captures a global property of the tree growth in a natural way. We prove that the Hausdorff and the packing dimension of this limiting measure is equal and constant with probability one. Moreover, the local dimension of mu equals the Hausdorff dimension at mu-almost every point. We give an explicit formula for the dimension, given the rule of attachment.

2010-01-01

116

DMSP Special Sensor Microwave/Imager Calibration ...  

Science.gov (United States)

... Using a weighted linear regression on randomly selected coincident SSM/I-buoy pairs from each of the climate m codes, it was possible to produce ...

2011-05-14

117

Catalog of War Games  

Science.gov (United States)

... Peripherals: 1 VT100 terminal and 1 high-speed ... Customer in ASP time Queue data ME ... TREATMEN OF RANDOMNESS: Stochastic, Monte Carlo. ...

1992-10-09

122

Start II, red ink, and Boris Yeltsin  

Energy Technology Data Exchange (ETDEWEB)

Apart from the vulnerability implied by the START II treaty, it will bear the burden of the general political opposition to the Yeltsin administration. START II will be seen as part of an overall Yeltsin-Andrei Kozyrev foreign policy that is under fire for selling out Russian national interests in Yugoslavia, the Persian Gulf, and elsewhere. This article discusses public opinion concerning START II, the cost of its implementation, and the general purpose of the treaty.

1993-04-01

123

Picture tour of Sasol II coal liquefaction plant  

Energy Technology Data Exchange (ETDEWEB)

This is a collection of photographs of the plant which is now almost completed.

1980-03-01

124

Performance of CDF calorimeter simulation for Tevatron Run II  

Energy Technology Data Exchange (ETDEWEB)

The upgraded CDF II detector has collected first data during the initial operation of the Tevatron accelerator in Run II. The simulation of the CDF electromagnetic and hadronic central and upgraded plug (forward) calorimeter is based on the Gflash calorimeter parameterization package used within the GEANT based detector simulation of the Run II CDF detector. We present the results of tuning the central and plug calorimeter response to test beam data.

2002-09-19

125

PRESTO-PREP: a data preprocessor for the PRESTO-II code  

Energy Technology Data Exchange (ETDEWEB)

PRESTO-II is a computer code developed to evaluate possible health effects from shallow land disposal of low level radioactive wastes. PRESTO-PREP is a data preprocessor that has been developed to expedite the formation of input data sets for PRESTO-II. PRESTO-PREP utilizes a library of nuclide and risk-specific data. Given an initial waste inventory, the code creates the radionuclide portion of the associated input data set for PRESTO-II. 2 references.

1984-07-01

128

Embedded computer systems for control applications in EBR-II  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this paper is to describe the embedded computer systems approach taken at Experimental Breeder Reactor II (EBR-II) for non-safety related systems. The hardware and software structures for typical embedded systems are presented The embedded systems development process is described. Three examples are given which illustrate typical embedded computer applications in EBR-II.

1993-01-01

133

Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells  

UK PubMed Central (United Kingdom)

Angiotensin II (Ang II) is a key proapoptotic factor in fibrotic tissue diseases. However, the mechanism of Ang-II-induced cell death in endothelial cells has not been previously elucidated....Full Text Available

2010-05-15

134

Mechanism of the metal-mediated carbalkoxylation of vinyl electrophiles. 1. Preparation, molecular structure, and alcoholysis of vinylic acyl platinum(II) complexes  

Energy Technology Data Exchange (ETDEWEB)

Carbalkoxylation of vinyl electrophiles was investigated using platinum complexes. This reaction occurs in two steps: (a) carbonyl insertion of {sigma}-vinyl Pt(II) halides and (b) alcoholysis of vinylic acyl Pt(II) complexes. Alcoholysis of vinylic acyl Pt(II) triflate complexes is investigated kinetically. Vinylic acyl Pt(II) complexes were isolated and characterized. 51 refs., 5 figs., 6 tabs.

1992-03-01

135

Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects  

UK PubMed Central (United Kingdom)

The effect of abatacept, a selective T-cell co-stimulation modulator, on vaccination has not been previously investigated. In this open-label, single-dose, randomized, parallel-group, controlled study,...Full Text Available

2007-01-01

136

Randomized controlled trials of the efficacy of lung cancer screening by sputum cytology revisited: a combined mortality analysis from the Johns Hopkins Lung Project and the Memorial Sloan-Kettering Lung Study  

UK PubMed Central (United Kingdom)

BackgroundTwo randomized controlled trials of lung cancer screening initiated in the 1970's, the Johns Hopkins Lung Project and the Memorial Sloan-Kettering Lung...Full Text Available

2009-11-01

137

Random motion of a particle emitting and absorbing tachyons  

International Nuclear Information System (INIS)

Random motion of a particle, emitting and absorbing tachyons, is investigated. It is shown that if bradyon is in equilibrium with neutral gas, i.e. it absorbs and emits tachyons, which do not have any charges, tha particle with each absorption-emittance of a tachyon changes its energy and momentum, never varying its own mass, and as a result it moves like a brownian particle. Thus, bradyon, interacting with tachyon gas, increases its momentum continuously in agreement with the Einstein-Fokker-Planck type equation.

138

A randomized trial of microdose leuprolide acetate protocol versus luteal phase ganirelix protocol in predicted poor responders  

British Library Electronic Table of Contents (United Kingdom)

We performed a randomized trial to compare IVF outcomes in 54 poor responder patients undergoing a microdose leuprolide acetate (LA) protocol or a GnRH antagonist protocol incorporating a luteal phase E2 patch and GnRH antagonist in the preceding menstrual cycle. Cancellation rates, number of oocytes retrieved, clinical pregnancy rates (PR), and ongoing PRs were similar between the two groups.

2011-01-01

139

Selective metabolic stimulation of the subfornical organ and pituitary neural lobe by peripheral angiotensin II  

Energy Technology Data Exchange (ETDEWEB)

The subfornical organ is a major receptor area for one of the principal stimuli of thirst, the octapeptide, angiotensin II. In conscious water-sated rats, the authors examined the effects of intravenous infusion of angiotensin II on the rate of glucose utilization in the subfornical organ and in structures anatomically and functionally connected with it. Angiotensin II produced pressor and drinking responses and increased glucose utilization selectively in the subfornical organ and pituitary neural lobe and in no other brain structure. Treatment with the angiotensin II antagonist, sar1-leu8-angiotensin II, before intravenous administration of angiotensin II prevented metabolic stimulation of the subfornical organ and neural lobe. Captopril, an inhibitor of angiotensin-converting enzyme, reduced subfornical organ glucose metabolism to a level similar to that ...

1985-01-01

140

Role of minerals in carbonaceous adsorbents for removal of Pb(II) ions from aqueous solution  

Energy Technology Data Exchange (ETDEWEB)

Adsorptive removal of Pb(II) ions from aqueous solution onto a non-activated charcoal (CC) of oak wood origin was studied in comparison with an activated carbon of coal origin. The adsorption capacity for Pb(II) of the non-activated charcoal increased significantly with deceasing particle diameter, whereas the activated carbon (AC) exhibited approximately constant capacity for Pb(II) adsorption as a function of particle size. Adsorption to the ashes prepared from the non-activated charcoal and the activated carbon was also investigated to examine the role of mineral ash. Although the ash from the activated carbon did not show any Pb(II) adsorption, the ash from the charcoal was very effective for Pb(II) adsorption. Furthermore, Pb(II) was hardly adsorbed when the ash was removed from the non-activated charcoal by acid treatment. Based on the results, the ...

2005-11-01

141

Biosorption of cadmium(II), zinc(II) and lead(II) by Penicillium simplicissimum: Isotherms, kinetics and thermodynamics  

Energy Technology Data Exchange (ETDEWEB)

The isotherms, kinetics and thermodynamics of Cd(II), Zn(II) and Pb(II) biosorption by Penicillium simplicissimum were investigated in a batch system. The effects of pH, initial metal ions concentration, biomass dose, contact time, temperature and co-ions on the biosorption were studied. Adsorption data were well described by both the Redlich-Peterson and Langmuir model. Chemical ion-exchange was found to be an important process based on free energy value from Dubini-Radushkevich isotherm for all metal ions. The results of the kinetic studies of all metal ions at different temperature showed that the rate of adsorption followed the pseudo second-order kinetics well. The thermodynamics constants {delta}G{sup o}, {delta}H{sup o} and {delta}S{sup o} of the adsorption process showed that biosorption of Cd(II), Zn(II) and Pb(II) ions on Penicillium simplicissimum ...

2008-12-30

142

Time-dependent, Bianchi II, rotating universe  

International Nuclear Information System (INIS)

An exact cosmological solution of Einstein's equations which has time-dependent rotation is presented. The t-constant sections are of Bianchi type II. The source of this geometry is a fluid which has not been thermalized. (Author).

2006-11-03

144

Site-specific modification of albumin by free radicals. Reaction with copper(II) and ascorbate.  

UK PubMed Central (United Kingdom)

Exposure of albumin to Cu(II) (10-100 microM) and ascorbate (0.1-2 mM) results in extensive molecular modifications, indicated by decreased fluorescence and chain breaks. The rate of utilization of...Full Text Available

1986-06-01

145

Rome II Versus Rome III Classification of Functional Gastrointestinal Disorders in Pediatric Chronic Abdominal Pain  

UK PubMed Central (United Kingdom)

ObjectivesThe updated Rome III criteria for pediatric functional gastrointestinal disorders (FGIDs) include new FGID categories and changes to the Rome II criteria...Full Text Available

2008-09-01

146

Presence of preactivated T cells in hemodialyzed patients: their possible role in altered immunity.  

UK PubMed Central (United Kingdom)

Interleukin 2 (IL-2) and B-cell growth factors I and II (BCGF I and BCGF II) are lymphokines produced by T cells that play a major role in T- and B-cell cooperation. Peripheral blood lymphocytes from...Full Text Available

1986-10-01

148

Plasma Electric Potential Evolution at the Core and Edge of the TJ-II Stellarator and T-10 Tokamak  

International Nuclear Information System (INIS)

In this article are presented main results on electric potential investigations in stellarator/torsatron TJ-II and tokamak T-10 in a comparable regimes of device operation.

2006-01-01

149

Partial Purification and Characterization of Aminopeptidase II from Chara australis  

UK PubMed Central (United Kingdom)

Aminopeptidase II, one of the two major aminopeptidases in the giant alga Chara australis, was partially purified. Its molecular weight was estimated to be about 80,000 by gel permeation...Full Text Available

1989-02-01

150

Palladium(II) and platinum(II) saccharinate complexes containing pyridine and 3-acetylpyridine: Synthesis, crystal structures, fluorescence and thermal properties  

British Library Electronic Table of Contents (United Kingdom)

New palladium(II) and platinum(II) complexes of saccharinate (sac), trans-[Pd(py)"2(sac)"2] (1), cis-[Pt(py)"2(sac)"2] (2), trans-[Pd(3-acpy)"2(sac)"2] (3) and cis-[Pt(3-acpy)"2(sac)"2] (4) (py=pyridine and 3-acpy=3-acetylpyridine) have been synthesized. Elemental analysis, UV-Vis, IR, NMR and TG/DTA characterizations have been carried out. The structures of 1-4 were determined by X-ray diffraction. The palladium(II) and platinum(II) ions are coordinated by two N-bonded sac ligands, and two nitrogen atoms of py or 3-acpy, forming a distorted square-planar geometry. The palladium(II) complexes (1 and 3) are trans isomers, while the platinum(II) complexes (2 and 4) are cis isomers. The mononuclear species in the solid state are connected by weak intermolecular C-H...O hydrogen bonds, C-H...@...

2011-01-01

152

MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes  

UK PubMed Central (United Kingdom)

BackgroundThe binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitopes...Full Text Available

153

Interactions of metal cations with anionic groups on the cell Wall of the macroalga vaucheria sp.  

Energy Technology Data Exchange (ETDEWEB)

The aim of this article was to investigate the interactions of metal cations in aqueous solutions with the biomass of the freshwater macroalga Vaucheria sp. This problem is important when elaborating new applications of biosorption, e.g. the production of mineral feed additives for livestock from the biomass of algae enriched with microelement ions. Potentiometric titration was applied as a quick and cheap screening test to search for new efficient biosorbents. It revealed a variety of functional groups capable of cation exchange on the macroalgal surface, including carboxyl, phosphate, hydroxyl or amino groups. Fourier transform infrared spectroscopy on natural and chromium-loaded Vaucheria sp. confirmed that carboxyl groups played a dominant role in the biosorption. The study also showed that Ca(II), Na(I), K(I), and Mg(II) ions were released from the biomass after biosorption of Cu(II), Mn(II), ...

2010-06-15

154

Human Pol II promoter recognition based on primary sequences and free energy of dinucleotides  

UK PubMed Central (United Kingdom)

BackgroundPromoter region plays an important role in determining where the transcription of a particular gene should be initiated. Computational prediction of eukaryotic Pol II promoter...Full Text Available

155

Examination of the Rotazyme II enzyme immunoassay for the diagnosis of rotavirus gastroenteritis.  

UK PubMed Central (United Kingdom)

Rotazyme II, which is a shorter version of Rotazyme (less than 3 h), was compared with electron microscopy and Rotazyme for sensitivity and specificity on 229 human stool specimens. Compared with electron...Full Text Available

1985-09-01

156

Equilibrium and thermodynamic parameters of single and binary mixture biosorption of lead (II) and copper (II) ions onto Pseudomonas putida: Effect of temperature  

Energy Technology Data Exchange (ETDEWEB)

The biosorption of lead (II) and copper (II) ions, single component and binary systems, by dried P. putida was investigated in a batch system. The effects of initial pH, temperature, initial single and binary mixture concentrations on the biosorption kinetics and equilibrium uptake of each component, both single and binary mixtures were investigated. The bacterial biomass exhibited the highest single and binary lead (II) and copper (II) ions uptake capacity at 25 and 30 deg. C, respectively, the initial pH value of 5.5 and at the initial metal ions concentration of 100 mg dm{sup -3}. The Freundlich and Langmuir adsorption models were used for the mathematical description of the biosorption equilibrium and isotherm constants were evaluated at different temperatures. Adsorption data were well described by the Langmuir model, although they could be modeled by the Freundlich equation. The thermodynamics ...

2006-07-31

157

Effects of Perfluorocarbons on surfactant exocytosis and membrane properties in isolated alveolar type II cells  

UK PubMed Central (United Kingdom)

BackgroundPerfluorocarbons (PFC) are used to improve gas exchange in diseased lungs. PFC have been shown to affect various cell types. Thus, effects on alveolar type II (ATII) cells...Full Text Available

2010-01-01

158

Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice  

UK PubMed Central (United Kingdom)

ATP-binding cassette A3 (ABCA3) is a lipid transport protein required for synthesis and storage of pulmonary surfactant in type II cells in the alveoli. Abca3 was conditionally deleted...Full Text Available

2010-05-01

159

Complex Impedance Studies of Electrosprayed and Extruded ...  

Science.gov (United States)

... Page 66 List of Figures Figure II.A.1 Simple Fuel Cell Model Page 8 ... Carbon Electrodes Figure II.A.1 Simple Fuel Cell Model Page 11. 9 ...

2004-05-05

160

Biphasic targeting and cleavage furrow ingression directed by the tail of a myosin II  

UK PubMed Central (United Kingdom)

Cytokinesis in animal and fungal cells utilizes a contractile actomyosin ring (AMR). However, how myosin II is targeted to the division site and promotes AMR assembly, and how the AMR coordinates with...Full Text Available

2010-12-27

161

Anaerobic reactions of Rhus vernicifera laccase and its type-2 copper-depleted derivatives with hexacyanoferrate(II).  

UK PubMed Central (United Kingdom)

Anaerobic reactions of Rhus vernicifera laccase and its type-2 copper-depleted derivatives with hexacyanoferrate(II) were investigated by absorption and e.s.r. spectroscopy. When native laccase was...Full Text Available

1992-06-15

162

Albumin binding of photobilirubin II.  

UK PubMed Central (United Kingdom)

Photobilirubin II, a stereoisomer of bilirubin, binds to human serum albumin at a single binding site (K = 2.2 x 10(6)M-1), presumably the high-affinity bilirubin-binding site. Binding in the secondary...Full Text Available

1983-07-01

163

A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach  

UK PubMed Central (United Kingdom)

The identification of MHC class II restricted peptide epitopes is an important goal in immunological research. A number of computational tools have been developed for this purpose, but there is a lack...Full Text Available

2008-04-01

164

1996 Hazardous Substances and New Organisms No. 30  

Wastenet

ii) Flammability: (iii) A capacity to oxidise: (iv) Corrosiveness: (v) Toxicity (including chronic ...an explosion or fire: (d) For substances with corrosive properties: (i) To reduce the ...likelihood of any unintended corrosion:(ii) To control the adverse effects of any corrosion:

165

Strategies and computational tools for improving randomized protein libraries.  

Science.gov (United States)

In the last decade, directed evolution has become a routine approach for engineering proteins with novel or altered properties. Concurrently, a trend away from purely 'blind' randomization strategies and towards more 'semi-rational' approaches has also become apparent. In this review, we discuss ways in which structural information and predictive computational tools are playing an increasingly important role in guiding the design of randomized libraries: web servers such as ConSurf-HSSP and SCHEMA allow the prediction of sites to target for producing functional variants, while algorithms such as GLUE, PEDEL and DRIVeR are useful for estimating library completeness and diversity. In addition, we review recent methodological developments that facilitate the construction of unbiased libraries, which are inherently more diverse than biased libraries and therefore more likely to yield improved variants. PMID:16095966

2005-10-01

166

Stability of modulation transfer function calibration of surface profilometers using binary pseudo-random gratings and arrays with nonideal groove shapes  

Energy Technology Data Exchange (ETDEWEB)

The major problem of measurement of a power spectral density (PSD) distribution of surface heights with surface profilometers arises due to the unknown Modulation Transfer Function (MTF) of the instruments, which tends to distort the PSD at higher spatial frequencies. The special mathematical properties of binary pseudo-random patterns make them an ideal basis for developing MTF calibration test surfaces. Two-dimensional binary pseudo-random arrays (BPRAs) have been fabricated and used for the MTF calibration of the MicroMap{trademark}-570 interferometric microscope with all available objectives. An investigation into the effects of fabrication imperfections on the quality of the MTF calibration and a procedure for accounting for such imperfections are presented.

2010-03-31

167

Optimal randomized control policy of an unreliable server system with second optional service and startup  

British Library Electronic Table of Contents (United Kingdom)

Purpose - To study the optimization of a randomized control problem in an M/G/1 queue in which a removable and unreliable server may provide two phases of heterogeneous service to arriving customers. Design/methodology/approach - Arriving customers follow a Poisson process and require the first essential service (FES). As soon as FES of a customer is completed, the customer may leave the system or opt for the second optional service (SOS). The service times of FES channel and SOS channel are assumed to be general distribution functions. The server requires a startup time with random length before starting service. When the server is working, he may meet unpredictable breakdowns but is immediately repaired. The inter-breakdown time and repair time of the removable server are exponentially r...

2008-01-01

168

Influence of shape on ordering of granular systems in two dimensions  

Energy Technology Data Exchange (ETDEWEB)

We investigate ordering properties of two-dimensional granular materials using several shapes created by welding ball bearings together. Ordered domains form much more easily in two than in three dimensions, even when configurations lack long-range order. The onset of ordered domains occurs near a packing density of 0.8, a phenomenon observed previously for disks. One of our shapes, the trapezoid, has packings that remain disordered and near the transition density even after annealing by shaking. Although random packings are unstable for disks and many other shapes in two dimensions, trapezoid packings provide an approach to studying two-dimensional randomness. We also find that the rotational symmetry of a shape is an excellent predictor of how easily it orders, and a potential guide to identifying two-dimensional shapes that remain random after annealing.

2001-06-01

169

Effect of nonsteroidal anti-inflammatory drug plasters for knee osteoarthritis in Japanese: a randomized controlled trial  

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to examine the effect of a nonsteroidal anti-inflammatory drug (NSAID) plaster for knee osteoarthritis among Japanese patients. An open-labeled, randomized, controlled, multiclinic trial was performed involving outpatient clinic groups. Two comparative groups?plaster NSAIDs and oral NSAIDs?were randomly allocated. The drugs used were limited to the current top three in both groups in Japan. Treatments were assessed after four?weeks and compared with the baseline scores. Outcomes were evaluated by two psychometric measures: Japanese knee osteoarthritis measure, and pain with the visual analogue scale. The total number of patients included in the final evaluation was 165 (87 for the plaster group and 78 for the oral group). Between these two groups there were ...

2010-01-01

170

Dixon's Theorem and random synchronization  

CERN Document Server

A transformation monoid on a set Omega is called synchronizing if it contains an element of rank 1 (that is, mapping the whole of Omega to a single point). In this paper, I tackle the question: given n and k, what is the probability that the submonoid of the full transformation monoid T_n generated by k random transformations is synchronizing? This question is analogous to Dixon's Theorem that two random permutations generate the symmetric or alternating group with high probability. Following the technique of Dixon's theorem, we need to analyse the maximal non-synchronizing submonoids of T_n. I develop a very close connection between transformation monoids and graphs, from which we obtain a description of non-synchronizing monoids as endomorphism monoids of graphs satisfying some very strong conditions. However, counting such graphs, and dealing with the intersections of their endomorphism monoids, seems difficult.

2011-01-01

171

Dirichlet mean identities and laws of a class of subordinators  

CERN Document Server

An interesting line of research is the investigation of the laws of random variables known as Dirichlet means. However, there is not much information on interrelationships between different Dirichlet means. Here, we introduce two distributional operations, one of which consists of multiplying a mean functional by an independent beta random variable, the other being an operation involving an exponential change of measure. These operations identify relationships between different means and their densities. This allows one to use the often considerable analytic work on obtaining results for one Dirichlet mean to obtain results for an entire family of otherwise seemingly unrelated Dirichlet means. Additionally, it allows one to obtain explicit densities for the related class of random variables that have generalized gamma convolution distributions and the finite-dimensional distribution of their associated L\\'{e}vy processes. ...

2010-01-01

172

A multi level analysis of non significant counseling effects in a randomized smoking cessation trial  

British Library Electronic Table of Contents (United Kingdom)

Abstract Aims To determine, in the context of a trial in which counseling did not improve smoking cessation outcomes, whether this was due to a failure of the conceptual theory identifying treatment targets or the action theory specifying interventions. Design Data from a randomized clinical trial of smoking cessation counseling and bupropion SR were submitted to multi level modeling to test whether counseling influenced real time reports of cognitions, emotions and behaviors, and whether these targets predicted abstinence. Setting Center for Tobacco Research and Intervention, Madison, WI. Participants A total of 403 adult, daily smokers without contraindications to bupropion SR use. Participants were assigned randomly to receive individual counseling or no counseling and a 9 week course o...

2010-01-01

174

To Repair or to Rebuild? Analyzing Personnel Security ...  

Science.gov (United States)

... Screening Adjudication Monitoring Applicants of Information Behavior II I Conducting Investigations ... Applicants of Information Behavior Conducting ...

1988-09-01

175

Titanate nanotubes as superior adsorbents for removal of lead(II) ions from water  

British Library Electronic Table of Contents (United Kingdom)

Titanate nanotubes were hydrothermally synthesized and their adsorption performances for lead(II) ion removal were studied. The results showed that titanate nanotubes ruptured in the adsorption process resulting in two distinct adsorption stages, thus achieving a maximum adsorption capacity of 3.752mmolg^-^1 of lead(II). Furthermore, it was found that the regeneration of titanate nanotubes loaded with the lead(II) ions can be readily achieved using the saturated EDTA disodium salt aqueous solution, thereby avoiding the trouble of disposal of adsorbent. The adsorption mechanism was also discussed in detail.

2010-01-01

177

STUDY OF BRUCELLA POLYSACCHARID ANTIGENES. II. ...  

Science.gov (United States)

... 1959). It was not possible for us, however, to detect any reaction of this type in the annials immunized with brucela. Considering ...

1965-04-26

179

JPRS Report, Nuclear Developments  

Science.gov (United States)

... II. Nuclear Purification Nuclear purity is achieved with the help of the treatment of commercial concentrates of uranium ("yellow cake"). ...

1988-06-03

180

Electroluminescence Study of Green Be-Contained II-VI ...  

Science.gov (United States)

... laser structure. However, still the greater part (60%) of emitted photons is a result of a spontaneous radiation process. In ...

2000-06-23

182

COST EVALUATION AND COST ESTIMATING FOR ...  

Science.gov (United States)

... Accession Number : AD0833945. Title : COST EVALUATION AND COST ESTIMATING FOR SHIPBOARD ELECTRONIC EQUIPMENT. VOLUME II. ...

1967-04-01

183

COMBUSTIBLE AMMUNITION FOR SMALL ARMS. 1. ...  

Science.gov (United States)

... Research on development of combustible cartridge cases for small arms was conducted in Germany during World War II. ...

1960-05-01

184

Adsorption of ammonia and pyridine on copper(II)-doped magnesium-exchanged smectite clays studied by electron spin resonance  

Science.gov (United States)

The interaction between N-donor adsorbates such as ammonia and pyridine with Cu(II)-exchanged montmorillonite, beidellite, flourohectorite into smectite clays has been studied by electron spin resonance. Cu(II) cations exchanged into smectites coordinate five ammonia or pyridine molecules in beidellite, four ammonia of pyridine molecules in hydroxyhectorite. Thus, the Cu(II) cations bound to the interior surfaces of these smectite clays constitute strong Lewis acid sites. 26 refs., 7 figs., 1 tab.

1993-01-14

185

A type II arabinogalactan isolated from an infusion of Maytenus ilicifolia  

International Nuclear Information System (INIS)

English 2005 [1 p.] Brazil Cipriani, TR Mellinger, CG Sassaki, GL Gorin,

2005-07-02

187

What, why, and when we image: considerations for diagnostic imaging and clinical research in the Children's Oncology Group  

Energy Technology Data Exchange (ETDEWEB)

Success in improving treatment outcomes in childhood cancer has been achieved almost exclusively through multicenter and multidisciplinary clinical and applied research over several decades. While biologically rational as well as empirical approaches have led to combination chemotherapy and multimodality approaches to therapy, which have given rise to evidence-based practice standards, similar scientific rigor has not always been as evidently applied to modalities utilized to assess initial disease burden and, more important, response to investigational approaches to therapy. As the empirical approach to therapeutic advances has likely maximized its benefit, future progress will require translation of biologic discovery most notably from the areas of genomics and proteomics. Hence, attempts to improve efficacy of therapy will require a parallel effort to minimize collateral damage of future therapeutic approaches, and such a parallel approach will mandate the ...

2009-02-15

188

Radiotherapy versus surgery in good-risk Ewing's sarcoma. An analysis of the CESS 86-data  

International Nuclear Information System (INIS)

The evaluation of radiotherapy and surgery as exclusive local treatment in comparably selected subgroups of patients with Ewing's sarcoma on the basis of the CESS 86-data. In the German multicenter Ewing's sarcoma study CESS 86, treatment consisted for four 9-week-courses of VACA- or VAIA-chemotherapy plus local therapy. VACA (vincristine, actinomycin D, cyclophosphamide, adriamycin) was given in low-risk extremity tumors with a tumor volume below 100 cm"3. Highrisk patients with central lesions or a tumor volume >100 m"3 received VAIA (ifosfamide instead of cyclophosphamide). Local therapy started after one complete chemotherapy course in week 10. Based on an individual decision in each patient, local therapy was either radical surgery or resection plus postoperative irradiation with 45 Gy or definitive radiotherapy with 60 Gy. Because of poor results with radiotherapy in a preceeding study, it was intended to restrict irradiation to patients with small ...

189

Pyridoxine dependent epilepsy and antiquitin deficiency Clinical and molecular characteristics and recommendations for diagnosis, treatment and follow-up.  

Science.gov (United States)

Antiquitin (ATQ) deficiency is the main cause of pyridoxine dependent epilepsy characterized by early onset epileptic encephalopathy responsive to large dosages of pyridoxine. Despite seizure control most patients have intellectual disability. Folinic acid responsive seizures (FARS) are genetically identical to ATQ deficiency. ATQ functions as an aldehyde dehydrogenase (ALDH7A1) in the lysine degradation pathway. Its deficiency results in accumulation of ?-aminoadipic semialdehyde (AASA), piperideine-6-carboxylate (P6C) and pipecolic acid, which serve as diagnostic markers in urine, plasma, and CSF. To interrupt seizures a dose of 100mg of pyridoxine-HCl is given intravenously, or orally/enterally with 30mg/kg/day. First administration may result in respiratory arrest in responders, and thus treatment should be performed with support of respiratory management. To make sure that late and masked response is not missed, treatment with oral/enteral pyridoxine should be continued until ATQ ...

2011-05-24

190

MACHO observations of Type II cepheids and RV Tauri Stars in the LMC  

Science.gov (United States)

We report the of the existence of RV Tauri stars in the Large Magellanic Cloud (LMC). This class of variable star has hitherto been unidentified in the Magellanic Clouds. In light and color curve behavior the RV Tauri stars appear to be an extension of the Type II Cepheids to longer periods. A single period-luminosity-color relationship is seen to describe both the Type II Cepheids and the RV Tauri stars in the LMC.

1996-07-01

191

Insulin-like growth factor II receptor is phosphorylated by a tyrosine kinase in adipocyte plasma membranes  

Energy Technology Data Exchange (ETDEWEB)

Incorporation of /sup 32/P from (gamma-32P)ATP into tyrosine residues of the insulin-like growth factor (IGF)-II receptor was observed in a Triton X-100-insoluble fraction of rat adipocyte plasma membranes. IGF-II receptor phosphorylation proceeded to a stoichiometry of approximately 0.5 mol of phosphate/IGF-II binding site after 10 min of incubation at 4 degrees C. A Km for ATP of 6 microM was calculated for this phosphorylation reaction. Addition of IGF-II caused an approximately 2-fold increase in tyrosine phosphorylation of the IGF-II receptor in this preparation. In contrast, phosphorylation of angiotensin II by the Triton X-100 washed membranes was not stimulated by IGF-II. Incubation of purified receptor immobilized on IGF-II agarose or of receptor-enriched low density microsomal membranes with (gamma-32P)ATP did ...

1986-06-15

192

Fragrance mix II in the baseline series contributes significantly to detection of fragrance allergy  

DEFF Research Database (Denmark)

Fragrance mix II (FM II) is a relatively new screening marker for fragrance contact allergy. It was introduced in the patch test baseline series in Denmark in 2005 and contains six different fragrance chemicals commonly present in cosmetic products and which are known allergens.

2010-01-01

193

Campylobacter jejuni Fatty Acid Synthase II: Structural and functional analysis of ?-hydroxyacyl-ACP dehydratase (FabZ)  

UK PubMed Central (United Kingdom)

Fatty acid biosynthesis is crucial for all living cells. In contrast to higher organisms, bacteria use a type II fatty acid synthase (FAS II) composed of a series of individual proteins, making...Full Text Available

2009-03-06

194

Tight Blood Glucose Control Is Renoprotective in Critically Ill Patients  

UK PubMed Central (United Kingdom)

Two large, prospective, randomized, controlled trials have shown a beneficial effect of intensive insulin therapy (IIT) on the kidney function of critically ill patients. The data from these trials...Full Text Available

2008-03-01

195

The relationship among current management systems, production, disease and drug usage on Ontario dairy farms.  

UK PubMed Central (United Kingdom)

The study involved 110 randomly selected dairy farms located in the Ontario, Canada counties of Bruce, Grey, Huron, Oxford, Perth, Waterloo and Wellington. Herds were classified as "intensive" and "extensive"....Full Text Available

1986-01-01

196

Substance Misuse Treatment for High Risk Chronic Pain Patients on Opioid Therapy: A Randomized Trial  

UK PubMed Central (United Kingdom)

Chronic pain patients who show aberrant drug-related behavior often are discontinued from treatment when they are noncompliant with their use of opioids for pain. The purpose of this study was...Full Text Available

2010-09-01

197

Steroid injections for shoulder disorders: a systematic review of randomized clinical trials.  

UK PubMed Central (United Kingdom)

BACKGROUND: Patients with shoulder disorders are believed to benefit considerably from steroid injections. However, the controversy about their efficacy persists. AIM: The study was designed to assess...Full Text Available

1996-05-01

198

Sisters in Motion: A Randomized Controlled Trial of a Faith-Based Physical Activity Intervention  

UK PubMed Central (United Kingdom)

ObjectiveTo evaluate a faith-based intervention (“Sisters in Motion”) intended to increase walking among older, sedentary African American women.Full Text Available

2010-10-01

200

Routine invasive management after fibrinolysis in patients with ST-elevation myocardial infarction: a systematic review of randomized clinical trials  

UK PubMed Central (United Kingdom)

BackgroundPatients with ST-elevation myocardial infarction (STEMI) treated with fibrinolysis are increasingly, and ever earlier, referred for routine coronary angiography and where...Full Text Available

201

Residential magnetic fields and childhood leukemia: a meta-analysis.  

UK PubMed Central (United Kingdom)

OBJECTIVES: This article uses meta-analysis methodology to examine the statistical consistency and importance of random variation among results of epidemiologic studies of residential magnetic field...Full Text Available

1998-12-01

202

Reduction of anti-malarial consumption after rapid diagnostic tests implementation in Dar es Salaam: a before-after and cluster randomized controlled study  

UK PubMed Central (United Kingdom)

BackgroundPresumptive treatment of all febrile patients with anti-malarials leads to massive over-treatment. The aim was to assess the effect of implementing malaria rapid diagnostic...Full Text Available

203

Randomized placebo-controlled trial on azithromycin to reduce the morbidity of bronchiolitis in Indigenous Australian infants: rationale and protocol  

UK PubMed Central (United Kingdom)

BackgroundAcute lower respiratory infections are the commonest cause of morbidity and potentially preventable mortality in Indigenous infants. Infancy is also a critical time for...Full Text Available

204

Randomized controlled trial comparing four strategies for delivering e-curriculum to health care professionals [ISRCTN88148532  

UK PubMed Central (United Kingdom)

BackgroundInternet education is increasingly provided to health professionals, but little is known about the most effective strategies for delivering the content. The purpose of...Full Text Available

205

Psychometric evaluation of a radio electric auricular treatment for stress related disorders: a double-blinded, placebo-controlled controlled pilot study  

UK PubMed Central (United Kingdom)

BackgroundThe aim of this double-blind randomized study is to test the efficacy of a radio electric stimulator device using an auricular reflex therapy protocol for stress-related...Full Text Available

206

Prospective randomized controlled trial of an injectable esophageal prosthesis versus a sham procedure for endoscopic treatment of gastroesophageal reflux disease  

UK PubMed Central (United Kingdom)

BackgroundThis study aimed to assess whether endoscopic implantation of an injectable esophageal prosthesis, the Gatekeeper Reflux Repair System (GK), is a safe and effective therapy...Full Text Available

2010-06-01

207

Precise Detection and Tracing of Trichoderma hamatum 382 in Compost-Amended Potting Mixes by Using Molecular Markers  

UK PubMed Central (United Kingdom)

Randomly amplified polymorphic DNA (RAPD) analysis and the PCR assay were used in combination with dilution plating on a semiselective medium to detect and enumerate propagules of Trichoderma...Full Text Available

1999-12-01

208

Post traumatic stress symptoms and heart rate variability in Bihar flood survivors following yoga: a randomized controlled study  

UK PubMed Central (United Kingdom)

BackgroundAn earlier study showed that a week of yoga practice was useful in stress management after a natural calamity. Due to heavy rain and a rift on the banks of the Kosi river,...Full Text Available

209

Orgasm is preserved regardless of ejaculatory dysfunction with selective ?1A-blocker administration  

UK PubMed Central (United Kingdom)

We evaluated whether ejaculatory dysfunction induced with a selective α1A-blocker influenced orgasm. Fifteen healthy male volunteers took silodosin or a placebo in a randomized, double-blind...Full Text Available

2009-09-01

210

No Effect of the Altered Peptide Ligand NBI-6024 on ?-Cell Residual Function and Insulin Needs in New-Onset Type 1 Diabetes  

UK PubMed Central (United Kingdom)

OBJECTIVEThis randomized, four-arm, placebo-controlled, dose-ranging phase 2 trial was conducted to determine whether repeated subcutaneous injections of the altered peptide ligand,...Full Text Available

2009-11-01

211

Negative Subtraction Hybridization: An efficient method to isolate large numbers of condition-specific cDNAs  

UK PubMed Central (United Kingdom)

BackgroundThe construction of cDNA libraries is a useful tool to understand gene expression in organisms under different conditions, but random sequencing of unbiased cDNA collections...Full Text Available

212

Myosin Motors Drive Long Range Alignment of Actin Filaments*  

UK PubMed Central (United Kingdom)

The bulk alignment of actin filament sliding movement, powered by randomly oriented myosin molecules, has been observed and studied using an in vitro motility assay. The well established,...Full Text Available

2010-02-12

213

Metacad programmer's guide  

Energy Technology Data Exchange (ETDEWEB)

Metacad is a collection of routines which creates a randomly accessible data structure from Applicon's APPLE-3D data format and supplies a logical method for manipulation of the data structure by a CAD application program.

1983-05-01

214

McMaster PLUS: A Cluster Randomized Clinical Trial of an Intervention to Accelerate Clinical Use of Evidence-based Information from Digital Libraries  

UK PubMed Central (United Kingdom)

BackgroundPhysicians have difficulty keeping up with new evidence from medical research.MethodsWe developed the McMaster Premium...Full Text Available

2006-11-01

215

Mass Treatment with Azithromycin for Trachoma Control: Participation Clusters in Households  

UK PubMed Central (United Kingdom)

BackgroundMass treatment to trachoma endemic communities is a critical part of the World Health Organization SAFE strategy. However, non-participation may not be at random, affecting...Full Text Available

216

Increased Ethanol Productivity in Xylose-Utilizing Saccharomyces cerevisiae via a Randomly Mutagenized Xylose Reductase?  

UK PubMed Central (United Kingdom)

Baker's yeast (Saccharomyces cerevisiae) has been genetically engineered to ferment the pentose sugar xylose present in lignocellulose biomass. One of the reactions controlling the...Full Text Available

2010-12-01

217

In vivo monitoring system for structure-function relationship analysis of the antibacterial peptide apidaecin.  

UK PubMed Central (United Kingdom)

A unique antibacterial peptide derivative found in immune honeybee lymph, apidaecin 1b (AP1), was randomly mutagenized and characterized by a newly established system to analyze in vivo its structure-function...Full Text Available

1994-10-01

218

Impact of repeated four-monthly anthelmintic treatment on Plasmodium infection in preschool children: a double-blind placebo-controlled randomized trial  

UK PubMed Central (United Kingdom)

BackgroundHelminth infections can alter susceptibility to malaria. Studies need to determine whether or not deworming programs can impact on Plasmodium infections...Full Text Available

219

Impact of a Computerized Clinical Decision Support System on Reducing Inappropriate Antimicrobial Use: A Randomized Controlled Trial  

UK PubMed Central (United Kingdom)

ObjectiveMany hospitals utilize antimicrobial management teams (AMTs) to improve patient care. However, most function with minimal computer support. We evaluated the effectiveness...Full Text Available

2006-07-01

220

Impact of Lifelong Sedentary Behavior on Mitochondrial Function of Mice Skeletal Muscle  

UK PubMed Central (United Kingdom)

This study investigated the impact of lifelong sedentariness on skeletal muscle mass and mitochondrial function. Thirty C57BL/6 strain mice (2 months) were randomly divided into three groups (young-Y;...Full Text Available

2009-09-01

221

Impact of Electronic Health Record Clinical Decision Support on Diabetes Care: A Randomized Trial  

UK PubMed Central (United Kingdom)

PURPOSE We wanted to assess the impact of an electronic health record–based diabetes clinical decision support system on control of hemoglobin A1c (glycated hemoglobin),...Full Text Available

2011-01-01

222

Identification and Disruption of Two Discrete Loci Encoding Hyaluronic Acid Capsule Biosynthesis Genes hasA, hasB, and hasC in Streptococcus uberis  

UK PubMed Central (United Kingdom)

The hyaluronic acid capsule of Streptococcus uberis has been implicated in conferring resistance to phagocytosis by bovine neutrophils. Construction of a bank of random insertion mutants...Full Text Available

2001-01-01

223

Healthy worker effect in the total Finnish population.  

UK PubMed Central (United Kingdom)

The selection due to the "healthy worker effect" was estimated from a random sample of the total Finnish population. The sample of 20 000 people was followed for changes in occupations from 1960 to...Full Text Available

1980-05-01

224

Health education for microcredit clients in Peru: a randomized controlled trial  

UK PubMed Central (United Kingdom)

BackgroundPoverty, lack of female empowerment, and lack of education are major risk factors for childhood illness worldwide. Microcredit programs, by offering small loans to poor...Full Text Available

225

Genome-wide profiling of forum domains in Drosophila melanogaster  

UK PubMed Central (United Kingdom)

Forum domains are stretches of chromosomal DNA that are excised from eukaryotic chromosomes during their spontaneous non-random fragmentation. Most forum domains are 50–200 kb in length....Full Text Available

2011-05-01

226

Genetic Diversity Assessment of Rarely Cultivated Traditional Indica Rice (Oryza sativa L.) Varieties  

UK PubMed Central (United Kingdom)

Random amplified polymorphic DNA fingerprinting was performed to assess the genetic diversity among rarely cultivated traditional indica rice (Oryza sativa ...Full Text Available

227

GeneSrF and varSelRF: a web-based tool and R package for gene selection and classification using random forest  

UK PubMed Central (United Kingdom)

BackgroundMicroarray data are often used for patient classification and gene selection. An appropriate tool for end users and biomedical researchers should combine user friendliness...Full Text Available

228

Frozen shoulder: prospective clinical study with an evaluation of three treatment regimens.  

UK PubMed Central (United Kingdom)

Forty-two patients with frozen shoulder were followed up closely for eight months. They were all taught pendular exercises and randomly allocated to one of four treatment groups: (a) intraarticular...Full Text Available

1984-06-01

229

Excitations and electromagnetic transitions for /sup 88/Sr and /sup 90/Zr  

Energy Technology Data Exchange (ETDEWEB)

An application of the renormalized random phase approximation to nuclear structure is presented for the semi-magic nuclei /sup 88/Sr and /sup 90/Zr. It is reported the outcome for the microscopic approach in comparison with the semiphenomenological version for the particle-hole forces.

1981-10-10

230

Evaluation of Conceptual Framework for Recruitment of African American Patients With Breast Cancer  

UK PubMed Central (United Kingdom)

Purpose/ObjectivesTo describe the Heiney-Adams Recruitment Framework (H-ARF); to delineate a recruitment plan for a randomized, behavioral trial (RBT) based on H-ARF;...Full Text Available

2010-05-01

231

Enhanced tube inner surface heat transfer device and method  

Science.gov (United States)

An inner surface substrate of metal tubes is provided with a single layer of randomly distributed metal bodies bonded to the substrate, spaced from each other, and substantially surrounded by the substrate to form body void space.

1979-05-15

232

Efficacy of sulphadoxine-pyrimethamine with or without artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in southern Mozambique: a randomized controlled trial  

UK PubMed Central (United Kingdom)

BackgroundAn artemisinin-based combination therapy, artesunate (AS) plus sulphadoxine-pyrimethamine (SP), was compared to SP monotherapy to provide evidence of further treatment...Full Text Available

233

Efficacy of a meal replacement diet plan compared to a food-based diet plan after a period of weight loss and weight maintenance: a randomized controlled trial  

UK PubMed Central (United Kingdom)

BackgroundObesity has reached epidemic proportions in the United States. It is implicated in the development of a variety of chronic disease states and is associated with increased...Full Text Available

234

Efficacy and safety of livwin (polyherbal formulation) in patients with acute viral hepatitis: A randomized double-blind placebo-controlled clinical trial  

UK PubMed Central (United Kingdom)

Objectives:The study was planned to evaluate the efficacy and safety of Livwin (polyherbal formulation) in acute viral hepatitis.Materials...Full Text Available

2010-10-01

235

Efficacy and cost-effectiveness of nutritional intervention in elderly after hip fracture: design of a randomized controlled trial  

UK PubMed Central (United Kingdom)

BackgroundHip fracture patients often have an impaired nutritional status at the time of fracture, which can result in a higher complication rate, prolonged rehabilitation time and...Full Text Available

236

Effect of a mixture of micronutrients, but not of bovine colostrum concentrate, on immune function parameters in healthy volunteers: a randomized placebo-controlled study  

UK PubMed Central (United Kingdom)

BackgroundSupplementation of nutritional deficiencies helps to improve immune function and resistance to infections in malnourished subjects. However, the suggested benefits of dietary...Full Text Available

237

Do calorie-controlled portion sizes of snacks reduce energy intake?  

UK PubMed Central (United Kingdom)

In a cross-over study, participants (n=59) were randomly assigned to receive either 100 kcal packs or standard size packages of snacks for 1-week. After a minimum of a 1-week washout period,...Full Text Available

2009-06-01

238

Delayed choice responding by pigeons when the correct response is not predictable from the sample stimulus.  

UK PubMed Central (United Kingdom)

Food-deprived pigeons were presented with a row of four response keys situated above a grain hopper aperture. At the start of a trial, three of four keys were randomly selected and illuminated white...Full Text Available

1982-01-01

239

Comparison between two shock wave regimens using frequencies of 60 and 90 impulses per minute for urinary stones  

UK PubMed Central (United Kingdom)

PURPOSE:Two different regimens of SWL delivery for treating urinary stones were compared.METHODS:Patients with urinary stones were randomly divided...Full Text Available

2010-10-01

240

Comparison between children and adolescents with and without chronic benign pain: consultation rate and pain characteristics.  

UK PubMed Central (United Kingdom)

The aim of the study was to determine whether children with chronic benign pain are in contact with their general practitioner (GP) more frequently than those without chronic benign pain. A random sample...Full Text Available

2002-03-01

241

Chemoprevention of Nonmelanoma Skin Cancer With Celecoxib: A Randomized, Double-Blind, Placebo-Controlled Trial  

UK PubMed Central (United Kingdom)

BackgroundPreclinical studies indicate that the enzyme cyclooxygenase 2 plays an important role in ultraviolet-induced skin cancers. We evaluated the efficacy and safety of celecoxib,...Full Text Available

2010-12-15

242

Changes in Tetracycline Susceptibility of Enteric Bacteria following Switching to Nonmedicated Milk Replacer for Dairy Calves?  

UK PubMed Central (United Kingdom)

A randomized intervention study was conducted to determine if discontinuing use of calf milk replacer medicated with oxytetracycline results in increased tetracycline susceptibility in Salmonella...Full Text Available

2008-06-01

243

Cardiovascular Safety of Degarelix: Results From a 12-Month, Comparative, Randomized, Open Label, Parallel Group Phase III Trial in Patients With Prostate Cancer  

UK PubMed Central (United Kingdom)

PurposeWe assessed the cardiovascular safety profile of degarelix, a new gonadotropin-releasing hormone antagonist.Materials...Full Text Available

2010-12-01

244

Barriers encountered during enrollment in an internet-mediated randomized controlled trial  

UK PubMed Central (United Kingdom)

BackgroundOnline technology is a promising resource for conducting clinical research. While the internet may improve a study's reach, as well as the efficiency of data collection,...Full Text Available

245

Assessment and management of patients with chronic cough by Certified Respiratory Educators: A randomized controlled trial  

UK PubMed Central (United Kingdom)

BACKGROUND:The value of other health care professionals is increasingly being recognized to compensate for the shortage of physicians in Canada. Chronic cough is one of the most...Full Text Available

2009-02-01

246

An Eating Disorder Randomized Clinical Trial & Attrition: Profiles & Determinants of Dropout  

UK PubMed Central (United Kingdom)

ObjectiveThis study sought to determine whether differential treatment effects in the targeted mechanisms of change and eating disorder (ED) symptoms are associated...Full Text Available

2011-05-01

247

After-Hours Information Given by Telephone by Family Physicians in Ontario  

UK PubMed Central (United Kingdom)

This study describes instructions for after-hours care offered by family physicians' offices when patients telephone the practice. Randomly selected (n=1,680) Ontario family physicians and general practitioners...Full Text Available

2009-11-01

248

A randomized-controlled trial of low-dose doxycycline for periodontitis in smokers  

UK PubMed Central (United Kingdom)

Background/AimTobacco use reduces the effect of non-surgical periodontal therapy. Host-modulation with low-dose doxycycline (LDD) might favour repair and promote...Full Text Available

2007-04-01

249

A prospective, randomized clinical trial comparing bipolar plasma kinetic resection of the prostate versus conventional monopolar transurethral resection of the prostate in the treatment of benign prostatic hyperplasia  

UK PubMed Central (United Kingdom)

BACKGROUND AND OBJECTIVE:For treatment of benign prostatic hyperplasia (BPH), Plasma Kinetic loop Resection of the Prostate (PKRP) is an alternative to conventional monopolar...Full Text Available

2009-11-01

250

A participatory parent-focused intervention promoting physical activity in preschools: design of a cluster-randomized trial  

UK PubMed Central (United Kingdom)

BackgroundWith rates of childhood obesity increasing, physical activity (PA) promotion especially in young children has assumed greater importance. Given the limited effectiveness...Full Text Available

251

A new analysis for membrane noise. The integral spectrum.  

UK PubMed Central (United Kingdom)

A new method of random data analysis has been developed with special implications for membrane noise. The integral spectrometer uses overlapping broad-band filters of simple design, whose bandwidth...Full Text Available

1976-07-01

252

A model for the single stranded random coil form of polydeoxyadenylic acid from minimum energy conformations of the dimeric subunit.  

UK PubMed Central (United Kingdom)

The minimum energy conformations of dApdA have been examined for their suitability as buildings blocks of the single stranded coil form of polynucleotides. Calculations of the characteristic ratio C...Full Text Available

1978-09-01

253

A Vasculature-Targeting Regimen of Pre-Operative Docetaxel with or without Bevacizumab for Locally Advanced Breast Cancer  

UK PubMed Central (United Kingdom)

PurposeTaxanes have effects on angiogenesis causing difficulties in separating biologic effects of chemotherapy from those due to angiogenesis inhibitors. This randomized...Full Text Available

2009-05-15

254

A Randomized Clinical Trial Investigating the Relationship Between Aprotinin and Hypercoagulability in Off-Pump Coronary Surgery  

UK PubMed Central (United Kingdom)

BACKGROUNDOff-pump coronary artery bypass (OPCAB) surgery is associated with a hypercoagulable state in which the platelet thrombin receptor, protease-activated receptor-1...Full Text Available

2009-11-01

255

A Patient-Centric, Provider-Assisted Diabetes Telehealth Self-management Intervention for Urban Minorities  

UK PubMed Central (United Kingdom)

This article describes the design and implementation of an online diabetes self-management intervention for a sample of inner-city African Americans with diabetes. Study participants were randomly assigned...Full Text Available

256

A Double Blind, Placebo-Controlled, Randomized Crossover Study of the Acute Metabolic Effects of Olanzapine in Healthy Volunteers  

UK PubMed Central (United Kingdom)

Background and RationaleAtypical antipsychotics exhibit metabolic side effects including diabetes mellitus and obesity. The adverse events are preceded by acute worsening of oral...Full Text Available

257

Twisted speckle entities inside wave-front reversal mirrors  

Science.gov (United States)

The previously unknown property of the optical speckle pattern reported. The interference of a speckle with the counterpropagating phase-conjugated (PC) speckle wave produces a randomly distributed ensemble of a twisted entities (ropes) surrounding optical vortex lines. These entities appear in a wide range of a randomly chosen speckle parameters inside the phase-conjugating mirrors regardless to an internal physical mechanism of the wave-front reversal. These numerically generated interference patterns are relevant to the Brillouin PC mirrors and to a four-wave mixing PC mirrors based upon laser trapped ultracold atomic cloud.

2009-07-15

258

Moderate Deviations for a Curie-Weiss model with dynamical external field  

CERN Document Server

In the present paper we prove moderate deviations for a Curie-Weiss model with external magnetic field generated by a dynamical system, as introduced by Dombry and Guillotin-Plantard. The results extend those already obtained in the case of a constant external field by Eichelsbacher and L\\"owe. The Curie-Weiss model with dynamic external field is related to the so called dynamic Z-random walks. We also prove a moderate deviation result for the dynamic Z-random walk, completing the list of limit theorems for this object.

2011-01-01

259

Implementation of the Random Forest method for the Imaging Atmospheric Cherenkov Telescope MAGIC  

Energy Technology Data Exchange (ETDEWEB)

The paper describes an application of the tree classification method Random Forest (RF), as used in the analysis of data from the ground-based gamma telescope MAGIC. In such telescopes, cosmic gamma-rays are observed and have to be discriminated against a dominating background of hadronic cosmic-ray particles. We describe the application of RF for this gamma/hadron separation. The RF method often shows superior performance in comparison with traditional semi-empirical techniques. Critical issues of the method and its implementation are discussed. An application of the RF method for estimation of a continuous parameter from related variables, rather than discrete classes, is also discussed.

2008-04-11

260

Cascade of Random Rotation and Scaling in a Shell Model Intermittent Turbulence  

International Nuclear Information System (INIS)

The time behaviors of intermittent turbulence in Gledzer-Ohkitani-Yamada model are investigated. Two kinds of orbits of each shell which is in the inertial range are discussed by portrait analysis in phase space. We find intermittent orbit parts wandering randomly and the directions of unstable quasi-periodic orbit parts of different shells form rotational, reversal and locked cascade of period three with shell number. We calculate the critical scaling of intermittent turbulence and the extended self-similarity of the two parts of orbit and point out that nonlinear scaling in inertial-range is decided by intermittent orbit parts.

2006-12-15

261

Broadcast Analysis for Large Cooperative Wireless Networks  

CERN Document Server

The capability of nodes to broadcast their message to the entire wireless network when nodes employ cooperation is considered. We employ an asymptotic analysis using an extended random network setting and show that the broadcast performance strongly depends on the path loss exponent of the medium. In particular, as the size of the random network grows, the probability of broadcast in a one-dimensional network goes to zero for path loss exponents larger than one, and goes to a nonzero value for path loss exponents less than one. In two-dimensional networks, the same behavior is observed for path loss exponents above and below two, respectively.

2011-01-01

262

A review of the probabilistic aspects of localized corrosion  

Energy Technology Data Exchange (ETDEWEB)

Localized corrosion has a stochastic character by nature. This character leads to an observed random behavior: fluctuations of the free potential, fluctuations of the current when a constant potential is maintained. This random signal, which is similar to an electric noise, can be analyzed either in the time domain by counting the events or in the frequency domain by measuring the power spectral density of the electrochemical noise. The experimental techniques developed for investigating the localized corrosion on the probabilistic point of view, i.e., statistical counting and power spectral density measurements, are discussed. Then the experimental results reported in the literature are reviewed in order to see what kind of parameters are accessible and how they can be related to the localized corrosion processes.

1990-04-01

263

A Greedy Randomized Adaptive Search Procedure for Technicians and Interventions Scheduling for Telecommunications  

CERN Document Server

The subject of the 5th challenge proposed by the French Society of Operations Research and Decision Analysis (ROADEF) consists in scheduling technicians and interventions for telecommunications (http://www.g-scop.inpg.fr/ChallengeROADEF2007/ or http://www.roadef.org/). We detail the algorithm we proposed for this challenge which is a Greedy Randomized Adaptative Search Procedure (GRASP). Computational results led us to the 1st position in the Junior category and to the 4th position in All category of the Challenge ROADEF 2007.

2007-01-01

264

Synthesis, Characterization and Biological Properties of Anions of Bivalent Transition Metal [Co(II) and Ni(II)] Complexes With Acylhydrazine Derived ONO Donor Schiff Bases.  

Science.gov (United States)

Some acylhydrazine derived ONO donor Schiff bases and their Co(II) and Ni(II) complexes have been prepared having the same metal ion (cation) but different anions. These synthesized metal(II) complexes have been characterized on the basis of their elemental analyses, magnetic moment, molar conductance, and IR and electronic spectral data. All of the Schiff base ligands function as tridentates and the deprotonated enolic form is preferred for coordination. In order to evaluate the effect of anions on the bactericidal activity, these synthesized complexes, in comparison to the uncomplexed Schiff bases have been screened against bacterial species., Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa and the results are reported. PMID:18475936

2000-01-01

265

EPR and luminescence studies of Eu(II) magnetically diluted in LiCl-KCl salt  

Energy Technology Data Exchange (ETDEWEB)

High-temperature LiCl-KCl molten salt medium provides an efficient way to produce the paramagnetic Eu(II) ion to be magnetically diluted into a diamagnetic host medium. Eu(II) was formed by a dissolution and an auto-reduction processes in a high-temperature LiCl-KCl eutectic melt at 723 K by using Eu{sub 2}O{sub 3} as a starting material. By using EPR and luminescence spectroscopic method, we studied the nature of the magnetically isolated paramagnetic Eu(II) ion diluted in a LiCl-KCl medium. With the aid of these spectroscopic tools, it was found that stable Eu(II) species was formed spontaneously at 723 K under anaerobic conditions. EPR and luminescence spectroscopy provided detailed information regarding the nature of the europium ion in a molten salt.

2007-12-15

266

EPR and luminescence studies of Eu(II) magnetically diluted in LiCl-KCl salt  

International Nuclear Information System (INIS)

High-temperature LiCl-KCl molten salt medium provides an efficient way to produce the paramagnetic Eu(II) ion to be magnetically diluted into a diamagnetic host medium. Eu(II) was formed by a dissolution and an auto-reduction processes in a high-temperature LiCl-KCl eutectic melt at 723 K by using Eu_2O_3 as a starting material. By using EPR and luminescence spectroscopic method, we studied the nature of the magnetically isolated paramagnetic Eu(II) ion diluted in a LiCl-KCl medium. With the aid of these spectroscopic tools, it was found that stable Eu(II) species was formed spontaneously at 723 K under anaerobic conditions. EPR and luminescence spectroscopy provided detailed information regarding the nature of the europium ion in a molten salt.

2007-12-01

267

EPR and luminescence studies of Eu(II) magnetically diluted in LiCl-KCl salt  

British Library Electronic Table of Contents (United Kingdom)

High-temperature LiCl-KCl molten salt medium provides an efficient way to produce the paramagnetic Eu(II) ion to be magnetically diluted into a diamagnetic host medium. Eu(II) was formed by a dissolution and an auto-reduction processes in a high-temperature LiCl-KCl eutectic melt at 723K by using Eu2O3 as a starting material. By using EPR and luminescence spectroscopic method, we studied the nature of the magnetically isolated paramagnetic Eu(II) ion diluted in a LiCl-KCl medium. With the aid of these spectroscopic tools, it was found that stable Eu(II) species was formed spontaneously at 723K under anaerobic conditions. EPR and luminescence spectroscopy provided detailed information regarding the nature of the europium ion in a molten salt.

2007-01-01

268

Chromosomal localization and structure of the human type II IMP dehydrogenase gene  

Energy Technology Data Exchange (ETDEWEB)

We determined the chromosomal localization and structure of the gene encoding human type II inosine 5{prime}-monophosphate dehydrogenase (IMPDH, EC 1.1.1.205), an enzyme associated with cellular proliferation, malignant transformation, and differentiation. Using polymerase chain reaction (PCR) primers specific for type II IMPDH, we screened a panel of human-Chinese hamster cell somatic hybrids and a separate deletion panel of chromosome 3 hybrids and localized the gene to 3p21.1{yields}p24.2. Two overlapping yeast artificial chromosome clones containing the full gene for type II IMPDH were isolated and a physical map of 117 kb of human genomic DNA in this region of chromosome 3 was constructed. The gene for type II IMPDH was localized and oriented on this map and found to span no more than 12.5 kb.

1994-05-01

269

A comparison of thermal maturity parameters between freely extracted hydrocarbons (Bitumen I) and a second extract (Bitumen II) from within the kerogen matrix of Permian and Triassic sedimentary rocks  

British Library Electronic Table of Contents (United Kingdom)

In this study we compared various maturity dependent aromatic, steroid and triterpenoid hydrocarbon ratios in bitumens that are freely extractable from sedimentary rocks (Bitumen I) with those in second extracts that comprised hydrocarbons closely associated with the kerogen/mineral matrix (Bitumen II). Bitumen II was released through kerogen isolation and demineralisation using HCl and HF/H3BO3. The samples studied, although of similar age, come from different localities. They represent a range of facies and two kerogen types (II and III), and all were deposited under marine conditions. The results show that the more stable b isomers of methylnaphthalene (MN) and methylphenanthrene (MP) are relatively more abundant in Bitumen II. The difference between the methylnaphthalene ratio (MNR) of...

2010-01-01

270

Biosorption of Cd(II), Ni(II) and Pb(II) from aqueous solution by dried biomass of aspergillus niger: application of response surface methodology to the optimization of process parameters  

Energy Technology Data Exchange (ETDEWEB)

In this study, the biosorption of Cd(II), Ni(II) and Pb(II) on Aspergillus niger in a batch system was investigated, and optimal condition determined by means of central composite design (CCD) under response surface methodology (RSM). Biomass inactivated by heat and pretreated by alkali solution was used in the determination of optimal conditions. The effect of initial solution pH, biomass dose and initial ion concentration on the removal efficiency of metal ions by A. niger was optimized using a design of experiment (DOE) method. Experimental results indicated that the optimal conditions for biosorption were 5.22 g/L, 89.93 mg/L and 6.01 for biomass dose, initial ion concentration and solution pH, respectively. Enhancement of metal biosorption capacity of the dried biomass by pretreatment with sodium hydroxide was observed. Maximal removal efficiencies for Cd(II), Ni(III) and ...

2009-10-15

271

Radiation reduction of dicarboxylatoimidazole platinum(II) complexes in the water-methanol system  

Energy Technology Data Exchange (ETDEWEB)

The radiation reduction of bis(1-ethylimidazole)tartratoplatinum(II) (EITPt(II)) complexes in methanol-water solution have been examined. The yields of Pt(I) depend on the presence of O{sub 2} in solutions as well as the dose applied. The rate constants of e{sub s}{sup -} scavenging by EITPt(II) and cis(diammine-1,1-cyclobutanedicarboxylato) platinum(II) (CBDCAPt(II)) have been determined by pulse radiolysis to be equal to 5.4 x 10{sup 9} and 6.4 x 10{sup 9} M{sup -1} s{sup -1}, respectively. The efficiencies of e{sub t}{sup -} scavenging by EITPt(II) and the rate of e{sub t}{sup -} photobleaching have also been determined in LiCl : H{sub 2}O : CH{sub 3}OH and MgCl{sub 2} : H{sub 2}O : CH{sub 3}OH glasses, respectively. (author).

1997-10-01

272

Theoretical study on antitumor activity of palladium(II) and platinum(II) complexes with isoxazole and its derivatives  

Energy Technology Data Exchange (ETDEWEB)

The palladium(II) and platinum(II)complexes(where, (M(L){sub 2}X{sub 2}), M=Pd(II), Pt(II); L=isoxazole (isox), 3, 5-dimethylisoxazole(3, 5-diMeisox), 3-methyl, 5-phenylisoxazole(3-Me, 5-Ph-isox), and 4-amino-3, 5-di-methylisoxazole (4-ADI); X=Cl, Br) with isoxazole and its derivatives were investigated on antitumor activity by MM2 and EHMO calculation. Because for all the complexes the {sigma}MO energy level (E{sub {sigma}}{sub (M-X)} between d{sub x}{sup 2}{sub -y}{sup 2} orbital of central metal and p{sub x} orbital of halogen atom is less than {sigma}MO energy level E{sub {sigma}}{sub (M-N)} between d{sub x}{sup 2}{sub -y}{sup 2} orbital of central metal and p{sub x} orbital of N atom, without exception. And judging, from the lower E{sub {sigma}}{sub (M-X)} value in trans, the bonding strength was found to be weaker in trans isomer than in cis. For the Pd(II) and ...

1998-02-01

273

Synthesis, crystal structure, spectroscopic and photoluminescence studies of manganese(II), cobalt(II), cadmium(II), zinc(II) and copper(II) complexes with a pyrazole derived Schiff base ligand  

British Library Electronic Table of Contents (United Kingdom)

Varying coordination modes of the Schiff base ligand H"2L [5-methyl-1-H-pyrazole-3-carboxylic acid (1-pyridin-2-yl-ethylidene)-hydrazide] towards different metal centers are reported with the syntheses and characterization of four mononuclear Mn(II), Co(II), Cd(II) and Zn(II) complexes, [Mn(H"2L)(H"2O)"2](ClO"4)"2(MeOH) (1), [Co(H"2L)(NCS)"2] (2), [Cd(H"2L)(H"2O)"2](ClO"4)"2 (3) and [Zn(H"2L)(H"2O)"2](ClO"4)"2 (4), and a binuclear Cu(II) complex, [Cu"2(L)"2](ClO"4)"2 (5). In the complexes 1-4 the neutral ligand serves as a 3N,2O donor where the pyridine ring N, two azomethine N and two carbohydrazine oxygen atoms are coordinatively active, leaving the pyrazole-N atoms inactive. In the case of complex 5, each ligand molecule behaves as a 4N,O donor utilizing the pyridine N, one azomethine N...

2011-01-01

274

Biosorption of Pb(II) and Cd(II) from aqueous solution using green alga (Ulva lactuca) biomass  

Energy Technology Data Exchange (ETDEWEB)

The biosorption characteristics of Pb(II) and Cd(II) ions from aqueous solution using the green alga (Ulva lactuca) biomass were investigated as a function of pH, biomass dosage, contact time, and temperature. Langmuir, Freundlich and Dubinin-Radushkevich (D-R) models were applied to describe the biosorption isotherm of the metal ions by U. lactuca biomass. Langmuir model fitted the equilibrium data better than the Freundlich isotherm. The monolayer biosorption capacity of U. lactuca biomass for Pb(II) and Cd(II) ions was found to be 34.7 mg/g and 29.2 mg/g, respectively. From the D-R isotherm model, the mean free energy was calculated as 10.4 kJ/mol for Pb(II) biosorption and 9.6 kJ/mol for Cd(II) biosorption, indicating that the biosorption of both metal ions was taken place by chemisorption. The calculated thermodynamic parameters ({delta}G{sup o}, ...

2008-03-21

275

Interaction of cis-diamminediaquoplatinum(II) with adenosylcobalamin and alkylcobalamins  

Energy Technology Data Exchange (ETDEWEB)

The interaction of cis-diamminediaquoplatinum(II) nitrate with adenosylcobalamin and a series of alkylcobalamins was studied by carbon-13 nuclear magnetic resonance spectroscopy and by electronic spectroscopy. With these cobalamins cis-(Pt(NH/sub 3/)/sub 2/(OH/sub 2/)/sub 2/)/sup 2 +/ forms adducts in which N(3) of the 5,6-methylbenzimidazole moiety is co-ordinated to platinum(II) rather than to cobalt(III) of the corrin. The chemical shifts of the 5'-methylene carbon of adenosylcobalamin-platinum adduct and of the Co-methyl carbon of the methylcobalamin-platinum adduct are characteristic of these cobalamins in the base-off form. Furthermore, these cobalamin-platinum complexes have visible spectra identical to those of the cobalamins in acidic solution. The /sup 13/C NMR spectrum of the adenosylcobalamin-platinum complex suggests the presence of a second adduct in which platinum(II) complexes are co-ordinated to ...

1980-01-01

276

Hybrid porous phosphate heterostructures as adsorbents of Hg(II) and Ni(II) from industrial sewage  

British Library Electronic Table of Contents (United Kingdom)

Porous phosphate heterostructures (PPH), functionalized with different ratios of aminopropyl and mercaptopropyl groups, labelled as Nx=5,25,50-PPH and Sx=5,25,50-PPH, respectively, were tested as adsorbents for Ni(II) and Hg(II) found in industrial sewage from electroplating processes and button battery recycling. X-ray diffraction was used to study the structures. The specific surface area of the pristine material (PPH) was 620m^2g^-^1, whereas the specific surface areas of the modified mercaptopropyl (S5-PPH) and aminopropyl (N5-PPH) were 472 and 223m^2g^-^1, respectively. The adsorption data were fitted to a Langmuir isotherm model. The S5-PPH material was saturated by 120mmol Hg(II) per 100g of material, whereas for Ni(II) adsorption, N25-PPH material displayed the highest adsorption w...

2011-01-01

277

Comparative examinations of serum pepsinogen I, II and gastric area using computed radiography in the atrophic gastritis  

Energy Technology Data Exchange (ETDEWEB)

The relationship between serum PG I, PG II levels and extent of atrophic gastritis was examined. The subjects were 64 patients (male: 32, female: 32, 51.9 years old on average) with established diagnosis of either atrophic gastritis or normal. In the X-ray gastric examination, Fuji Computed Radiography (FCR) was used to obtain clear-cut images of the gastric area. Concerning the serum PG I level, patients in the group with atrophic gastritis showed lower levels than those of the people in the group with no atrophic change, but the variation was wide, and no definite tendency was seen in the relationship between the atrophic change and the serum PG I levels. Concerning the serum PG II level, as the atrophic change progresses, the serum PG II level tended to increase gradually. A significant reduction in the PG I/II ratio was seen in the group with atrophic changes (p<0.01) in comparison with the group ...

1995-11-01

278

Comparative examinations of serum pepsinogen I, II and gastric area using computed radiography in the atrophic gastritis  

International Nuclear Information System (INIS)

The relationship between serum PG I, PG II levels and extent of atrophic gastritis was examined. The subjects were 64 patients (male: 32, female: 32, 51.9 years old on average) with established diagnosis of either atrophic gastritis or normal. In the X-ray gastric examination, Fuji Computed Radiography (FCR) was used to obtain clear-cut images of the gastric area. Concerning the serum PG I level, patients in the group with atrophic gastritis showed lower levels than those of the people in the group with no atrophic change, but the variation was wide, and no definite tendency was seen in the relationship between the atrophic change and the serum PG I levels. Concerning the serum PG II level, as the atrophic change progresses, the serum PG II level tended to increase gradually. A significant reduction in the PG I/II ratio was seen in the group with atrophic changes (p<0.01) in comparison with the group ...

1995-01-01

279

Biosorption of cadmium(II) from aqueous solution by red algae (Ceramium virgatum): Equilibrium, kinetic and thermodynamic studies  

Energy Technology Data Exchange (ETDEWEB)

The biosorption characteristics of Cd(II) ions using the red alga (Ceramium virgatum) were investigated. Experimental parameters affecting the biosorption process such as pH, contact time, biomass dosage and temperature were studied. Langmuir, Freundlich and Dubinin-Radushkevich (D-R) models were applied to describe the biosorption isotherms. The biosorption capacity of C. virgatum biomass for Cd(II) ions was found to be 39.7 mg/g. From the D-R isotherm model, the mean free energy was calculated as 12.7 kJ/mol, indicating that the biosorption of Cd(II) the metal ions was taken place by chemisorption. The calculated thermodynamic parameters ({delta}G{sup o}, {delta}H{sup o} and {delta}S{sup o}) showed that the biosorption of Cd(II) ions onto C. virgatum was feasible, spontaneous and exothermic at 293-323 K. Evaluation of experimental data in terms of biosorption kinetics showed that the biosorption of ...

2008-09-15

280

Apparent molar volumes and apparent molar heat capacities of aqueous nickel(II) nitrate, copper(II) nitrate, and zinc(II) nitrate at temperatures from (278.15 to 393.15) K at the pressure 0.35 MPa  

Energy Technology Data Exchange (ETDEWEB)

Apparent molar volumes V{sub phi} and apparent molar heat capacities C{sub p,phi} were determined for aqueous solutions of nickel(II) nitrate, copper(II) nitrate, and zinc(II) nitrate at molalities m=(0.01 to 0.5) mol {center_dot} kg{sup -1}, and at the pressure p=0.35 MPa. Solution densities obtained using a vibrating-tube densimeter at T=(278.15 to 368.15) K were used to calculate V{sub phi} values. Heat capacity measurements obtained with a twin fixed-cell, differential-output, power-compensating, temperature-scanning calorimeter at T=(278.15 to 393.15) K were used to calculate values of C{sub p,phi}. Our results were then fitted to functions of m and T and compared to literature values.

2004-05-01

281

Impact of more intensive written information in patients having radical radiation therapy: Results of a prospective randomized phase III trial  

International Nuclear Information System (INIS)

Background and purpose: A diagnosis of malignancy and its treatment is a very stressful time for patients and their families. This study was conducted to determine the impact of more intensive written information on patients' anxiety levels. The secondary aim was to determine the impact of this information on patients' satisfaction levels. Materials and methods: This prospective randomized trial consisted of patients with a pathological diagnosis of cancer having radical radiotherapy (RT). Patients were randomized to receive the more intensive information (including written information and a telephone call from the research nurse) or not to receive the more intensive information at the time of their initial consultation with the radiation oncologist. Study questionnaires measuring anxiety (STAI form) were completed prior to their first consultation (baseline) at the time of simulation (pre-RT) and at the completion of radiotherapy. A second ...

2010-08-01

282

GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries.  

Science.gov (United States)

There are many methods for introducing random mutations into nucleic acid sequences. Previously, we described a suite of programmes for estimating the completeness and diversity of randomized DNA libraries generated by a number of these protocols. Our programmes suggested some empirical guidelines for library design; however, no information was provided regarding library diversity at the protein (rather than DNA) level. We have now updated our web server, enabling analysis of translated libraries constructed by site-saturation mutagenesis and error-prone PCR (epPCR). We introduce GLUE-Including Translation (GLUE-IT), which finds the expected amino acid completeness of libraries in which up to six codons have been independently varied (according to any user-specified randomization scheme). We provide two tools for assisting with experimental design: CodonCalculator, for assessing amino acids corresponding to given ...

2008-04-28

283

Effect of grain boundary microstructures of brittle fracture in polycrystalline molybdenum  

Energy Technology Data Exchange (ETDEWEB)

Superplasticity can be generally achieved by grain boundary sliding (GBS). The GBS in polycrystalline materials sometimes accompanies with intergranular fracture because of stress concentrations at triple points and/or GB irregularities. To develop the superplastic flow, it is necessary to suppress the intergranular cracking. In the present study, therefore, polycrystalline molybdenum with distinct GB microstructures, such as grain boundary character distribution (GBCD), has been employed to clarify the relationship between fracture behaviour and GB microstructures. Microstructures were analyzed using a FE-SEM/EBSP/OIM system prior to 4-points bending tests at 77K, thereafter, crack propagation was observed. The main results obtained are as follows. Stress fluctuations on stress - strain curves were observed for specimens with random oriented grains, whereas such behaviour rarely occurred for ones with textured grains. Difference in the behaviour would result from ...

1999-07-01

284

Water chemistry in the water-vapor circuit at Angra II: evolution of the operational concepts and canceling of the condensed polishing system; Quimica da agua do circuito agua-vapor de Angra II: evolucao do conceito operacional e o cancelamento do sistema de polimento do condensado  

Energy Technology Data Exchange (ETDEWEB)

The chemical operational concept originally established for the water-steam circuit of Angra II nuclear power plant has undergone several modifications throughout the development of the project. This work discusses the two main modifications giving special attention to the costs involved and analyses the main points and the consequences of such modifications 1 ref., 4 figs., 2 tabs.

1995-12-31

285

Performance testing of the Ford/GE Second Generation Single-Shaft Electric Propulsion (ETX-II) System  

Energy Technology Data Exchange (ETDEWEB)

System-level-operational testing of the ETX-II test-bed electric vehicle is described and the results discussed. Because the traction battery is a major factor in the performance of an electric vehicle, previously reported work on the sodium-sulfur battery designed for use with the ETX-II is reviewed in detail. Chassis dynamometer performance of the test-bed vehicle met or exceeded design goals and compared reasonably well with SIMPLEV computer modeling results. Areas are identified wherein further work is needed to establish a firmer basis for comparison of the simulation and the observed results.

1993-06-01

286

#mu#C/OS-II the real-time kennel and its new progress  

International Nuclear Information System (INIS)

A lot of effort has been made to spread the application of RTOS in embedded system development in China. RTOS, #mu#C/OS and #mu#C/OS-II, with its opened source code, is well known in embedded systems. Learning RTOS, Using RTOS, becomes more and more popular. The Book of 'Micro C/OS-II The Real-Time Kennel Second Edition' was published in 2002. Here some new progress of the RTOS, especially the safety certifications, the reliability of software is introduced. (authors)

2003-09-08

287

iII1TEImETFlIES - NASA Technical Report Server (NTRS)  

Science.gov (United States)

The various sources of inertial navigation error are discussed in Section 2.2. It is the nature of inertial navigation errors ...

289

The development of an integrated multistaged fluid bed retorting process. Technical report, October 1, 1992--December 31, 1992  

Energy Technology Data Exchange (ETDEWEB)

The KENTORT II process includes integral fluidized bed zones for pyrolysis, gasification, and combustion of the oil shale. The purpose of this program is to design and test the KENTORT II process at the 50-lb/hr scale. Along with the major activity of assembling the components of the 50-lb/hr retort, work was also completed in other areas this quarter. Basic studies of the cracking and coking kinetics of model compounds in a fixed bed reactor were continued. Additionally, as part of the effort to investigate niche market applications for KENTORT II-derived products, a study of the synthesis of carbon fibers from the heavy fraction of KENTORT II shale oil was initiated.

1993-01-01

290

Temperature measurements of the EK-10 type reactor fuel rods in EWA-4 core  

International Nuclear Information System (INIS)

... ked by ! I ; II III IV Table 4. Temperatute distributions along the fuel rod at a

291

Stellar evolution. II - The evolution of a 3 sun-mass star from the main sequence through core helium burning.  

Science.gov (United States)

Three Sun-mass star evolution from main sequence to helium exhaustion in core, noting chronology of

1965-01-01

292

State II Dissociation Element Formation Following Activator Excision in Maize  

UK PubMed Central (United Kingdom)

Active Activator (Ac) elements undergo mutations to become nonautonomous Dissociation (Ds) elements at a low frequency. To understand...Full Text Available

2007-10-01

295

Satellite Calibration Data. Annual Data Report - 1977  

Science.gov (United States)

... in Taylor and Williamson.* Most satellite sensors cannot be ... The coordinates of the rocket Ii ... I - Incoming Global Radiant Flux between 0.285 and ...

1979-08-01

296

SAR of Cu (II) Thiosemicarbazone Complexes as Hypoxic Imaging Agents: MM3 Analysis and Prediction of Biologic Properties  

British Library Electronic Table of Contents (United Kingdom)

Abstract Copper(II) bis(thiosemicarbazone) are very useful for blood flow and hypoxic imaging. The aim of this study was to identify structure-activity relationships (SARs) within a series of analogues with different substitution patterns in the ligands, in order to design improved hypoxia imaging agents and elucidate hypoxia selectivity mechanisms. Genetic algorithms (GAs) were used to develop specific copper metal-ligand force field parameters for the MM3 force-field calculations. These new parameters produced results in good agreement with experiment and previously reported copper metal-ligand parameters. A successful quantitative SAR (QSAR) for predicting the several classes of Cu(II)-chelating ligands was built using a training set of 21 Cu(II) complexes. The QSAR exhibited a correlat...

2010-01-01

299
300

Reasoning About Action II: The Quali cation Problem  

Science.gov (United States)

missionaries and cannibals puzzle. He noted that in order to be able to use a boat to cross a river one would need ... a quali cation that the vertical exhaust stack ...

303

Perception/Action: An Holistic Approach II  

Science.gov (United States)

... And those who study cognition select problems (eg, tower of Hanoi, missionaries and cannibals, logic theorems) with minimal perceptual and motor ...

1993-10-12

304

PPT - AstroGravS - NASA  

Science.gov (United States)

Form as the end result of massive star evolution; Type II supernova: collapse of iron core in highly evolved massive star; outer regions blasted away in ...

305

Materials Research Science and Engineering Centers (MRSEC)  

Science.gov (United States)

... centers in materials research. MRSECs address fundamental materials research topics of intellectual ... in materials research. II. PROGRAM DESCRIPTION MRSECs are supported by NSF to undertake materials ...

306

Lead, copper and zinc biosorption from bicomponent systems modelled by empirical Freundlich isotherm  

Energy Technology Data Exchange (ETDEWEB)

The biosorption of lead, copper and zinc ions on Rhizopus arrhizus has been studied for three single-component and two binary systems. The equilibrium data have been analysed using the Freundlich adsorption model. The characteristic parameters for the Freundlich adsorption model have been determined and the competition coefficients for the competitive biosorption of Pb(II)-Cu(II) at pH 4.0 and 5.0, and Pb(II)-Zn(II) at pH 5.0 have been calcualted. For the individual single-component isotherms, lead has the highest biosorption capacity followed by copper, then zinc. The capacity of lead in the two binary systems is always significantly greater than those of the other metal ions, in agreement with the single-component data. Only a partial selectivity for copper ions has been obtained at pH 4.0. (orig.)

2000-07-01

307

Kim IL Sung (North Korea), Another Saddam Hussein (Iraq)? ...  

Science.gov (United States)

... 10 Page 16. 1987, and (3) numerous infiltration excursions including attempted sabotage of the Wolsung nuclear plant in 1987. Kim Ii ...

1992-02-13

308

Inclusive w and z cross section measurements at the Fermilab Tevatron  

Energy Technology Data Exchange (ETDEWEB)

The present recent measurements of the inclusive cross section of W and Z bosons from Run II of the Fermilab Tevatron collider.

2004-12-01

309

Heavy Metals in Vehicles II  

Wastenet

Hexavalent chromium in corrosion preventive coating 64 ...To prevent corrosion of rims, weights can be provided with a coating. ...integrated clips brought up technical problems due to corrosion

311

Flue gas desulfurization pilot study: summary of phase I and phase II reports  

Science.gov (United States)

The initial phase of this study consisted of a survey of existing FGD systems used on larger combustion processes in the NATO countries and Japan.

1980-04-01

312

FAQs for IIS Solicitation NSF-05551  

Science.gov (United States)

... Science, Computer Vision, Digital Government, Digital Libraries, Digital Society and Technologies ... for Robust Intelligence, Digital Government, and Digital Libraries and Archives. In subsequent years ...

313

Evaluation of Meal, Ready-to-Ear VIII at Market Square 2  

Science.gov (United States)

... Ready-to-Eat (MRE) VIII operational ration was evaluated at a field training exercise (Market Square II) with troops of the 82nd Airborne Division. ...

1988-09-01

314

E 1  

Science.gov (United States)

3l the c I coir is ometimes ca I led "re I I "I angie of the IPP; ii) the cone ( sometimes ca I led "I coir") angle of the {PP . ...

317

Clinical Investigation Program, Reports Control Symbol MED ...  

Science.gov (United States)

... POG Cook, BA A Case Control Study of Childhood 147 8552(85) Rhabdomyosarcoma (0) POG COOK, BA Phase II Study of 6-Mercaptopurine ...

1988-10-01

318

Balance with Unbounded Complexes  

CERN Document Server

Given a double complex $X$ there are spectral sequences with the $E_2$ terms being either H$_I$ (H$_{II}(X))$ or H$_{II}($H$_I (X))$. But if $H_I(X)=H_{II}(X)=0$ both spectral sequences have all their terms 0. This can happen even though there is nonzero (co)homology of interest associated with $X$. This is frequently the case when dealing with Tate (co)homology. So in this situation the spectral sequences may not give any information about the (co)homology of interest. In this article we give a different way of constructing homology groups of $X$ when H$_I(X)=$H$_{II}(X)=0$. With this result we give a new and elementary proof of balance of Tate homology and cohomology.

2011-01-01

320

Annual Research Progress Report. Fiscal Year 1989. Volume ...  

Science.gov (United States)

... Rhabdomyosarcoma. (0) 511 PO 8561 Phase II Study of 6- Mercaptopurine Administered as an Intra- 512 venous Infusion ...

1989-10-01

321

Annual Research Progress Report, Fiscal Year 1988. Volume ...  

Science.gov (United States)

... Rhabdomyosarcoma. (0) 505 POG 8561 Phase II Study of 6- Mercaptopurine Administered as an Intra- 506 venous Infusion ...

1988-10-01

322

Adsorbent-adsorbate interactions in the adsorption of organic and?inorganic species on ozonized activated carbons: a?short?review  

British Library Electronic Table of Contents (United Kingdom)

This objective of this work was to summarize the main results obtained in previous papers related to the adsorbent-adsorbate interactions involved in the adsorption of naphthalenesulphonic acids and heavy metals (Cd(II) or Hg(II)) by modified activated carbons. The adsorption of organic compounds (1-naphthalenesulphonic acid, 1,5-naphthalenedisulphonic acid and 1,3,6-naphthalenetrisulphonic acid) and inorganic species (Cd(II) and Hg(II)) was studied on a series of ozonized activated carbon in aqueous phase. Commercial activated carbon (Filtrasorb 400) was treated with different ozone doses to study the effect of ozone treatment on its surface properties and investigate the behavior of the treated carbon samples in the above adsorption processes. After ozonation, carbonyl- and carboxyl-type...

2011-01-01

323

User-friendly algorithms for estimating completeness and diversity in randomized protein-encoding libraries.  

Science.gov (United States)

Directed evolution of proteins depends on the production of molecular diversity by random mutagenesis. While a number of methods have been developed for introducing this diversity, the best ways to sample it are not always clear. Here we used simple statistics to analyse completeness and diversity in randomized libraries generated by oligonucleotide-directed mutagenesis, error-prone polymerase chain reaction (epPCR) and in vitro recombination of highly homologous sequences. For oligonucleotide-directed mutagenesis, we derive equations to estimate how complete a given library is expected to be and also to predict the size of library required to give a fixed probability of being 100% complete. We describe the statistical bases for computer programs which estimate the number of distinct variants represented in epPCR and shuffled libraries, dubbed PEDEL and DRIVeR, respectively. These programs allow the user to calculate (rather than guess) the ...

2003-06-01

324

Stochastic-convective transport with nonlinear reaction: Mathematical framework  

Energy Technology Data Exchange (ETDEWEB)

A stochastic-convective reactive (SCR) transport method is developed for one-dimensional steady transport in physically heterogeneous media with nonlinear degradation. The method is free of perturbation amplitude limitations and circumvents the difficulty of scale dependence of phenomenological parameters by avoiding volume-averaged specifications of diffusive/dispersive fluxes. The transport system is conceptualized as an ensemble of independent convective-reactive streamlines, each characterized by a randomized convective velocity (or travel time). Dispersive effects are treated as a component of the randomness in the streamline velocity ensemble, so no explicit expression for hydrodynamic dispersive flux is written in the streamline transport equation. The expected value of the transport over the stream tube ensemble is obtained as an average of solutions to the reactive convection equation according to the stream tube (travel time) ...

1995-11-01

325

Signal Processing in Large Systems: a New Paradigm  

CERN Document Server

For a long time, signal processing applications, and most particularly detection and parameter estimation methods, have relied on the limiting behaviour of test statistics and estimators, as the number n of observations of a population grows large comparatively to the population size N, i.e. n>>N. Modern technological and societal advances now demand the study of sometimes extremely large populations, while simultaneously requiring fast signal processing due to accelerated system dynamics; this results in not-so-large practical ratios n/N, sometimes even smaller than one. A disruptive change in classical signal processing methods has therefore been initiated in the past ten years, mostly spurred by the field of large dimensional random matrix theory. The early literature in random matrix theory for signal processing applications is however scarce and highly technical. This tutorial proposes an accessible methodological introduction to the ...

2011-01-01

326

Orbital roulette: a new method of gravity estimation from observed motions  

CERN Document Server

The traditional way of estimating the gravitational field from observed motions of test objects is based on the virial relation between their kinetic and potential energy. We find a more efficient method. It is based on the natural presumption that the objects are observed at a random moment of time and therefore have random orbital time phases. The proposed estimator, which we call "orbital roulette", checks the randomness of the phases. The method has the following advantages: (1) It estimates accurately Keplerian (point-mass) potentials as well as non-Keplerian potentials where the unknown gravitating mass is distributed in space. (2) It is a complete statistical estimator: it checks a trial potential and accepts it or rules it out with a certain significance level; the best-fit measurement is thus supplemented with error bars at any confidence level. (3) It needs no a priori assumptions about the distribution of orbital ...

2004-01-01

327

Iodixanol in cerebral computed tomography: a randomized, double-blind, phase-III, parallel study with iodixanol and iohexol  

International Nuclear Information System (INIS)

Iodixanol is a new nonionic dimer, isotonic with blood at all clinically relevant concentrations. Iodixanol (270 mg I/ml) was compared in a double-blind, randomized, parallel-group, phase-III study to the monomeric nonionic iohexol (300 mg I/ml) for evaluation of safety, tolerability and radiographic efficacy during cerebral CT. One hundred adult patients scheduled to undergo contrast-enhanced cerebral CT were randomly allocated to receive either iodixanol or iohexol. All completed the trial. Safety was evaluated by recording discomfort and other adverse events, tolerance by assessing intensity and incidence of discomfort. Radiographic efficacy was assessed from the diagnostic information and the radiographic density. No serious adverse events occurred. One patient (2 %) in the iodixanol group and one patient (2 %) in the iohexol group experienced a transient reddening at the neck and lower neck-line, respectively. Both contrast agents were ...

1999-09-01

328

Interpolation between Airy and Poisson statistics for unitary chiral non-Hermitian random matrix ensembles  

CERN Document Server

We consider a family of chiral non-Hermitian Gaussian random matrices in the unitarily invariant symmetry class. The eigenvalue distribution in this model is expressed in terms of Laguerre polynomials in the complex plane. These are orthogonal with respect to a non-Gaussian weight including a modified Bessel function of the second kind, and we give an elementary proof for this. In the large $n$ limit, the eigenvalue statistics at the spectral edge close to the real axis are described by the same family of kernels interpolating between Airy and Poisson that was recently found by one of the authors for the elliptic Ginibre ensemble. We conclude that this scaling limit is universal, appearing for two different non-Hermitian random matrix ensembles with unitary symmetry. As a second result we give an equivalent form for the interpolating Airy kernel in terms of a single real integral, similar to representations for the asymptotic kernel in the bulk ...

2010-01-01

329

Dynamic security assessment in electric power systems  

Energy Technology Data Exchange (ETDEWEB)

A new approach to dynamic security assessment in electric power systems is proposed. A power system is modeled as a dynamical system with random variable structure. Structural variations are caused by primary and secondary events. Primary events are state-independent disturbances representing line and unit faults and load changes and are modeled by random jump processes. Secondary events that represent forced line and unit outages and load sheddings are modeled through an aggregate representation of the protection system as random processes whose change in time corresponds to the crossing of switching surfaces by the state process. These switching surfaces are defined by the setting of the protective relays. Commensurate with this model a three-state decomposition of the operating conditions into normal, emergency, and partial load operating states is suggested. Transitions between these states are described in terms of ...

1983-01-01

330

Trigeminocardiac Reflex, Bilateral Sagittal Split Ramus Osteotomy, Gow-Gates Block: A Randomized Controlled Clinical Trial  

British Library Electronic Table of Contents (United Kingdom)

PurposeThe behavior of trigeminocardiac reflex (TCR) during maxillofacial surgeries has not yet been sufficiently studied and knowledge of its behavior is limited to some case reports. The present study aimed to assess the occurrence of TCR in bilateral sagittal split ramus osteotomy and to determine the possible effect of Gow-Gates block on its incidence. Materials and MethodsTwenty candidates for bilateral sagittal split ramus osteotomy (included were American Society of Anesthesiologists I Class III patients with a prognathism of 3 to 5 mm) were given routine general anesthesia after at least 12 hours of fasting. All patients received Gow-Gates mandibular nerve block on 1 random side (case ramus; the other side was used as the control) after induction of general anesthesia before surger...

2011-01-01

331

The cost effectiveness of cognitive behavioral therapy for bulimia nervosa delivered via telemedicine versus face-to-face  

British Library Electronic Table of Contents (United Kingdom)

Objective A number of effective treatments for bulimia nervosa have been developed, but they are infrequently used, in part due to problems with dissemination. The goal of this study was to examine the cost effectiveness of telemedicine delivery of cognitive behavioral therapy for bulimia nervosa. Method A randomized controlled trial of face-to-face versus telemedicine cognitive behavioral therapy for bulimia nervosa. One hundred twenty eight women with DSM-IV bulimia nervosa or eating disorder, not otherwise specified subsyndromal variants of bulimia nervosa were randomized to 20 sessions of treatment over 16 weeks. A cost effectiveness analysis from a societal perspective was conducted. Results The total cost per recovered (abstinent) subject was $9324.68 for face-to-face CBT, and $7300....

2009-01-01

332

Soy isoflavones, diet and physical exercise modify serum cytokines in healthy obese postmenopausal women  

British Library Electronic Table of Contents (United Kingdom)

Objectives: Evaluate the effect of diet, physical exercise, and a daily oral intake of a soy isoflavones extract (Fisiogen) contained 200mg of Glycine max, which corresponded to 80mg of isoflavone (60.8mg of genistein, 16mg of daidzein and 3.2mg of glicitein) on leptin and other adipokines plasma levels in healthy obese postmenopausal women. Methods: A multicentric randomized longitudinal prospective cohort study was conducted in a sample of 87 healthy obese postmenopausal women. Patients were randomly assigned to a 1200kcal diet and exercise group (control group) or a group of 1200kcal diet, exercise, and daily oral intake of daily oral intake of a soy isoflavones extract (Fisiogen) contained 200mg of Glycine max, which corresponded to 80mg of isoflavone (60.8mg of genistein, 16mg of daid...

2011-01-01

333

South African consumers' opinions and consumption of soy and soy products  

British Library Electronic Table of Contents (United Kingdom)

Abstract Interest in soy foods has increased with consumer awareness of its health benefits, especially with soy-related ingredients being utilized as one of the major sources of high-protein fortification. The aim of the present study was to assess South African (SA) consumers' opinion of soy and soy products through different statements on consumption, taste, protein value and healthiness. The respondents (n = 3001) for this randomized cross-sectional study were randomly selected from metropolitan and rural areas in South Africa. Trained fieldworkers administered questionnaires by conducting face-to-face interviews. Fourteen statements from four sections of the questionnaire (consisting of 17 food-related topics in total), probing information on consumers' opinion on soy and soy products...

2009-01-01

334

Single phase polycrystalline metastable (GaSb)/sub 1-x/Ge/sub x/ alloys from annealing of amorphous mixtures: Ion mixing effects during deposition  

International Nuclear Information System (INIS)

Low energy (<100 eV) Ar"+ ion bombardment of the growing film during the deposition of amorphous GaSb+Ge mixtures was found to affect both the transformation rate kinetics as well as the reaction path during subsequent annealing. Ion bombardment induced collisional cascades resulted in more random mixing in the growing films thus retarding the rate of the amorphous to equilibrium state phase transformation during annealing and allowing the formation of homogeneous metastable randomly oriented single phase (GaSb)/sub 1-x/Ge/sub x/ alloys. The films were approx.1.5 #mu#m thick and the average grain size in the metastable state was approx.300 A.

6180-01-01

335

Secure Direct Communication Based on Non-Orthogonal Entangled Pairs and Local Measurement  

Science.gov (United States)

We propose a quantum secure direct communication scheme based on non-orthogonal entangled pairs and local measurement. In this scheme, we use eight non-orthogonal entangled pairs to act as quantum channels. Due to the non-orthogonality of the quantum channels, the present protocol can availably prohibit from all kinds of valid eavesdropping and acquire a secure quantum channel. By local measurement, the sender acquires a secret random sequence. The process of encoding on the random sequence is identical to the one in one-time-pad. So the present protocol is secure. Even for a highly lossy channel, our scheme is also valid. The scheme is feasible with present-day techniques.

2008-12-01

336

Second generation antipsychotics (SGAs) for non-psychotic disorders in children and adolescents: A review of the randomized controlled studies  

British Library Electronic Table of Contents (United Kingdom)

In children and adolescents the Second Generation Antipsychotics (SGAs) represent the class of psychotropic drugs whose use has grown more significantly in recent years: they are primarily used for treatment of patients with disruptive behavior disorders, mood disorders and pervasive developmental disorders or mental retardation. In order to compare the efficacy and tolerability of antipsychotics against placebo or each other, a systematic Medline/PubMed search for randomized, double blind studies on SGA in patients younger than 18years of age at enrolment, was conducted. Papers on schizophrenia, discussed in another article of this specific issue, were excluded by the efficacy analysis. A set of standard efficacy and safety indices, such as treatment effect sizes (ES), the Numbers Needed ...

2011-01-01

337

Role of Intravenous Omeprazole in Patients with High-Risk Peptic Ulcer Bleeding After Successful Endoscopic Epinephrine Injection: A Prospective Randomized Comparative Trial  

British Library Electronic Table of Contents (United Kingdom)

BACKGROUND: Epinephrine injection is the most common endoscopic therapy for peptic ulcer bleeding. Controversy exists concerning the optimal dose of proton pump inhibitors (PPI) for patients with bleeding peptic ulcers after successful endoscopic therapy. The objective of this study was to determine the optimal dose of PPI after successful endoscopic epinephrine injection in patients with bleeding peptic ulcers. METHODS: A total of 200 peptic ulcer patients with active bleeding or nonbleeding visible vessels (NBVV) who had obtained initial hemostasis with endoscopic injection of epinephrine were randomized to receive omeprazole 40 mg infusion every 6 h, omeprazole 40 mg infusion every 12 h or cimetidine (CIM) 400 mg infusion every 12 h. Outcomes were checked at 14 days after enrollment. RE...

2006-01-01

338

Random walk function in the analysis of time-activity curves from dynamic radionuclide studies  

Energy Technology Data Exchange (ETDEWEB)

The random walk function is a mathematical function derived from studies of the mass transport and flow of diffusible materials through tubes. Approximations to the function were first used some time ago in the field of cardiac tracer dilution curves, but in the absence of rapid and reproducible curve fitting the method never became commonplace. The current study uses the latest curve-fitting techniques and shows how the method may be used with precision in the analysis of time-activity curves from dynamic oesophageal and blood flow studies. The physiological basis of the method is given and parameters obtained which relate to both the rate of flow and the local dispersion of the bolus.

1987-04-01

339

Psychological mediators of bupropion sustained-release treatment for smoking cessation  

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT Aim The study aimed to test simultaneously our understanding of the effects of bupropion sustained-release (SR) treatment on putative mediators and our understanding of determinants of post-quit abstinence, including withdrawal distress, cigarette craving, positive affect and subjective reactions to cigarettes smoked during a lapse. The specificity of bupropion SR effects was also tested in exploratory analyses. Design Data from a randomized, placebo-controlled clinical trial of bupropion SR were submitted to mediation analyses. Setting Center for Tobacco Research and Intervention, Madison, WI, USA. Participants A total of 403 adult, daily smokers without contraindications to bupropion SR use. Intervention Participants were assigned randomly to receive a 9-week course of bupropion...

2008-01-01

340

Pseudospectral method calculation of tidal field and particle random walk simulation of radionuclides in Daya Bay  

International Nuclear Information System (INIS)

Presented here is the calculation results of tidal field of Daya Bay by using pseudospectral method. According to the calculation results about the tidal field and measured value of wind in Daya Bay area, the diffusion of radionuclide from Daya Bay Nuclear Power Plant is simulated by using particle random walk model. The simulation results about the relative concentration distribution of the radionuclides and the trajectory of the distribution centrode are obtained, taking account of tidal current, wind and turbulent current. These results can provide information not only for the reasonable discharge of the radionuclides from Daya Bay Nuclear Power Plant, but also for understanding the potential effect on environment due to the normal operation of Daya Bay Nuclear Power Plant. (authors)

2009-11-01

341

Opinion fluctuations and disagreement in social networks  

CERN Document Server

We study a stochastic gossip model of continuous opinion dynamics in a society consisting of two types of agents: regular agents, who update their beliefs according to information that they receive from their social neighbors; and stubborn agents, who never update their opinions and might represent leaders, political parties or media sources attempting to influence the beliefs in the rest of the society. When the society contains stubborn agents with different opinions, opinion dynamics never lead to a consensus (among the regular agents). Instead, beliefs in the society almost surely fail to converge, and the belief of each regular agent converges in law to a non-degenerate random variable. The model thus generates long-run disagreement and continuous opinion fluctuations. The structure of the social network and the location of stubborn agents within it shape opinion dynamics. When the society is ``highly fluid'', meaning that the mixing time of the ...

2010-01-01

342

Observation of 77 K staircase I-V characteristics in 2DEG's irradiated by a focused ion beam  

International Nuclear Information System (INIS)

Staircase current-voltage (I-V) characteristics, observed at 77 K in narrow 2DEG channels irradiated by a single line scan of a focused ion beam (FIB), is reported in detail. These staircases are interpreted as evidence of single electron tunneling through a naturally occurring specific Coulomb island in the random potential fluctuations created by FIB damage. Clear comparison is made between the I-V's taken from wide channels and those from narrow channels. Based on orthodox calculations of the I-V characteristics, it is shown that highly asymmetric tunnel junctions are needed to explain our data. This is consistent with the random nature of the potential landscape in the FIB damaged region. (author).

343

Mary Lyon and the hypothesis of random X chromosome inactivation  

British Library Electronic Table of Contents (United Kingdom)

The 50th anniversary of Mary Lyon?s 1961 Nature paper, proposing random inactivation in early embryonic life of one of the two X chromosomes in the cells of mammalian females, provides an opportunity to remember and celebrate the work of those involved. While the hypothesis was initially put forward by Lyon based on findings in the mouse, it was founded on earlier studies, notably the work of Susumu Ohno; it was also suggested independently by Beutler and colleagues using experimental evidence from a human X-linked disorder, glucose-6-phosphate dehydrogenase deficiency, and has proved to be of as great importance for human and medical genetics as it has for general mammalian genetics. Alongside the hypothesis itself, previous cytological studies of mouse and human chromosomes, and the obse...

2011-01-01

344

Is exposure to silica associated with lung cancer in the absence of silicosis? A meta-analytical approach to an important public health question  

British Library Electronic Table of Contents (United Kingdom)

Objective This report investigates epidemiologically whether exposure to silica is associated with lung cancer risks in individuals without silicosis. Methods We searched the PubMed reference data base from 1966 through 1/2007 for reports of lung cancer in silica-exposed persons without and with silicosis. To explore heterogeneity between studies, a multi-stage strategy was employed. First, fixed-effect summaries (FES) and corresponding 95% confidence intervals (CI) for various combinations of studies were calculated, weighting individual results by their precision. The homogeneity of the contributing results was examined using ?2 statistics. Where there was evidence of substantial heterogeneity, the CI around the FES was increased to take account of the between-study variability. Random-e...

2009-01-01

345

Explicit Randomness is not Necessary when Modeling Probabilistic Encryption  

CERN Document Server

Although good encryption functions are probabilistic, most symbolic models do not capture this aspect explicitly. A typical solution, recently used to prove the soundness of such models with respect to computational ones, is to explicitly represent the dependency of ciphertexts on random coins as labels. In order to make these label-based models useful, it seems natural to try to extend the underlying decision procedures and the implementation of existing tools. In this paper we put forth a more practical alternative based on the following soundness theorem. We prove that for a large class of security properties (that includes rather standard formulations for secrecy and authenticity properties), security of protocols in the simpler model implies security in the label-based model. Combined with the soundness result of (\\textbf{?}) our theorem enables the translation of security results in unlabeled symbolic models to computational security.

2006-01-01

346

Experimental and theoretical study of periodic intensity bursts in the start-up phase of a free-electron laser oscillator  

International Nuclear Information System (INIS)

In this paper experimental observations and a theoretical analysis of periodic radiation bursts and macropulse formation in the start-up phase of a free-electron laser (FEL) oscillator are presented. This microwave FEL uses a long pulse electron beam with a slowly decaying voltage. The output radiation consists of a superposition of bell-shaped macropulses, each of which is composed of a periodic sequence of short micropulses. The micropulses are separated by a cavity round-trip time. Each bell-shaped macropulse has a random start-up time and amplitude. The startup of the radiation macropulses is correlated with random current spikes on the continuous electron beam. The observed macropulse signal agrees with a theoretical calculation of the impulse response of the FEL oscillator when the shift in the FEL resonance frequency arising from the slow voltage drop of the electron beam is included in the analysis. Possible applications of the ...

347

Effectiveness of different music-playing devices for reducing preoperative anxiety: A clinical control study  

British Library Electronic Table of Contents (United Kingdom)

Background: While waiting for surgery, patients often exhibit fear and anxiety. Music is thought to be an alternative to medication to relieve anxiety. However, due to concerns about infection control, devices other than headphones may be considered for this purpose. Objectives: The purpose of this study was to determine the anxiety-relieving effect of broadcast versus headphone music playing for patients awaiting surgery. Design: A randomized controlled clinical study. Setting: The waiting area of an operating theater of a metropolitan teach hospital in Taiwan. Participants: Alert adult with age between 20 and 65 years old waiting for surgery without premedications. Methods: A total of 167 patients were randomly assigned to the headphone, broadcast and control groups. Both the headphone a...

2011-01-01

348

Binary pseudo-random grating as a standard test surface formeasurement of modulation transfer function of interferometricmicroscopes  

Energy Technology Data Exchange (ETDEWEB)

The task of designing high performance X-ray optical systemsrequires the development of sophisticated X-ray scattering calculationsbased on rigorous information about the optics. One of the mostinsightful approaches to these calculations is based on the powerspectral density (PSD) distribution of the surface height. The majorproblem of measurement of a PSD distribution with an interferometricand/or atomic force microscope arises due to the unknown ModulationTransfer Function (MTF) of the instruments. The MTF characterizes theperturbation of the PSD distribution at higher spatial frequencies. Here,we describe a new method and dedicated test surfaces for calibration ofthe MTF of a microscope. The method is based on use of a speciallydesigned Binary Pseudo-random (BPR) grating. Comparison of atheoretically calculated PSD spectrum of a BPR grating with a spectrummeasured with the grating provides the desired calibration of theinstrumental MTF. The theoretical ...

2007-07-25

349

The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors  

UK PubMed Central (United Kingdom)

In order to study the intragenic profiles of active transcription, we determined the relative levels of active RNA polymerase II present at the 3′- and 5′-ends of 261 yeast genes by...Full Text Available

2010-08-01

350

Temporal patterns of protein phosphorylation after angiotensin II, A23187 and/or 12-O-tetradecanoylphorbol 13-acetate in adrenal glomerulosa cells.  

UK PubMed Central (United Kingdom)

The temporal patterns of protein phosphorylation in the adrenal glomerulosa cell were analysed by two-dimensional electrophoresis after stimulation with 10 nM-angiotensin II or various agents [10 nM-12-O-tetradecanoylphorbol...Full Text Available

1986-09-15

352

Structural Investigations of Silica Polyamine Composites: Surface Coverage, Metal Ion Coordination, and Ligand Modification  

Science.gov (United States)

Silanization of the silica gel surface in the synthesis of silica gel polyamine composites uses (chloropropyl)-trichlorosilane (CPTCS). It is possible to substitute a molar fraction of reagent CPTCS with methyltrichlorosilane (MTCS), creating a mixed silane surface layer. Two types of silica gels were modified with a series of MTCS:CPTCS molar ratios. Solid-state CP/MAS 29Si and 13C NMR spectroscopies were used to evaluate the surface silane composition. Surface silane coverage was markedly improved for the resulting gels. When polyamines were grafted to the resultant MTCS:CPTCS silane layers, it was shown that the decrease in the number of propyl attachments to the polyamine resulted in increased quantities of ''free amines''. Optimum MTCS:CPTCS ratios were determined for three polyamines grafted onto one silica gel. A substantial free amine increase was observed for poly(allylamine) (PAA). Metal uptake studies show increases in ...

2006-09-13

353

Structural Investigations of Silica Polyamine Composites: Surface Coverage, Metal Ion Coordination, and Ligand Modification  

Energy Technology Data Exchange (ETDEWEB)

Silanization of the silica gel surface in the synthesis of silica gel polyamine composites uses (chloropropyl)-trichlorosilane (CPTCS). It is possible to substitute a molar fraction of reagent CPTCS with methyltrichlorosilane (MTCS), creating a mixed silane surface layer. Two types of silica gels were modified with a series of MTCS:CPTCS molar ratios. Solid-state CP/MAS 29Si and 13C NMR spectroscopies were used to evaluate the surface silane composition. Surface silane coverage was markedly improved for the resulting gels. When polyamines were grafted to the resultant MTCS:CPTCS silane layers, it was shown that the decrease in the number of propyl attachments to the polyamine resulted in increased quantities of ''free amines''. Optimum MTCS:CPTCS ratios were determined for three polyamines grafted onto one silica gel. A substantial free amine increase was observed for poly(allylamine) (PAA). Metal uptake studies show increases in ...

2006-09-13

354

Spin-up of He II in a cylindrical vessel of finite height  

Energy Technology Data Exchange (ETDEWEB)

The spin-up problem of He II in a cylindrical container of infinite and finite height is considered on the basis of the Hall-Vinen-Bekarevich-Khalatnikov equations. The boundary conditions include the assumption of the generation of superfluid vorticity at the walls of the container. In the lowest order approximation with respect to viscosity, the problem is reduced to a Stefan problem for a single diffusion-type equation. Examples of solutions are given which show that the method used gives a good insight into the physical development of the spin-up flow.

1990-01-01

355

New Insights into Type II NAD(P)H:Quinone Oxidoreductases  

UK PubMed Central (United Kingdom)

Type II NAD(P)H:quinone oxidoreductases (NDH-2) catalyze the two-electron transfer from NAD(P)H to quinones, without any energy-transducing site. NDH-2 accomplish the turnover of NAD(P)H, regenerating...Full Text Available

2004-12-01

356

Lithium isotope ratio in Population II halo dwarfs - a proposed test of the late decaying massive particle nucleosynthesis scenario  

Energy Technology Data Exchange (ETDEWEB)

It is shown that observations of the lithium isotope ratio in high surface temperature Population II stars may be critical to cosmological nucleosynthesis models. In particular, decaying particle scenarios as derived in some supersymmetric models may stand or fall with such observations. 18 references.

1988-06-01

357

Liposome technology. Volume II: Incorporation of drugs, proteins and genetic material  

Energy Technology Data Exchange (ETDEWEB)

These three volumes cover liposome technology in pharmacology and medicine. Contributors emphasize methodology used in their own laboratories, and include a brief introduction, coverage of relevant literature, applications and critical evaluations for the methods they describe. Volume II presents procedures for the entrapment of a number of drugs, including genetic material, into selected types of liposomes.

1984-01-01

358

Evolution of a horizontal branch Population II star with total mass 0.63 Msub solar  

Science.gov (United States)

The theoretical evolution of a horizontal branch star of Population II is followed through the helium burning in the core phase and is compared with the results given by other investigators. The m- fluence of different physics and interpolation schemes in the opacity tables is discussed. Some thoughts are given on the explanation of the erratic period variations observed in some of the RR Lyrae variables in the globular clusters. (auth)

1973-01-01

359

Effects of electric field on the II-III phase transition in lithium ammonium sulphate and its deuterated analogue  

International Nuclear Information System (INIS)

Experimental results are presented on the quasi-statistic polarization reversal and on the effect of high dc electric field on the behaviour of LiNH_4SO_4 and LiND_4SO_4 monocrystals, namely in the vicinity of the II-III phase transformation.

1984-03-01

360

Dose specification and quality assurance of RTOG protocol 95-17; a cooperative group study of 192Ir breast implants as sole therapy  

UK PubMed Central (United Kingdom)

PurposeRTOG protocol 95-17 was a phase I/II trial to evaluate multi-catheter brachytherapy as the sole method of adjuvant breast radiotherapy for stage I/II breast...Full Text Available

2007-12-01

361

Comparison of SAND-II and FERRET  

Science.gov (United States)

A comparison was made of the advantages and disadvantages of two codes, SAND-II and FERRET, for determining the neutron flux spectrum and uncertainty from experimental dosimeter measurements as anticipated in the FFTF Reactor Characterization Program. This comparison involved an examination of the methodology and the operational performance of each code. The merits of each code were identified with respect to theoretical basis, directness of method, solution uniqueness, subjective influences, and sensitivity to various input parameters.

362

Can SST-II contain the standard model  

Energy Technology Data Exchange (ETDEWEB)

The answer to the title is ''NO''. The authors investigate the low energy particle spectra of type-II superstring theory after compactification to 4 dimensional space-time by means of the super Kac-Moody algebra as well as the twisted super Kac-Moody algebra. They show that there is no solution containing all of the particle contents in the standard model.

1988-11-01

363

Aurantimonas manganoxydans, sp. nov. and Aurantimonas litoralis, sp. nov.: Mn(II) oxidizing representatives of a globally distributed clade of alpha-Proteobacteria from the order Rhizobiales  

UK PubMed Central (United Kingdom)

Several closely related Mn(II)-oxidizing alpha-Proteobacteria were isolated from very different marine environments: strain SI85-9A1 from the oxic/anoxic interface of a stratified...Full Text Available

2009-04-01

364

A study of the interactions of some polypyridylruthenium (II) complexes with DNA using fluorescence spectroscopy, topoisomerisation and thermal denaturation.  

UK PubMed Central (United Kingdom)

The nature of binding of Ru(phen) 2+ (I), Ru(bipy) 2+ (II), Ru(terpy) 2+ (III) (phen = 1,10-phenanthroline, bipy 3 = 2,2'-bipyridyl, 3 terpy = 2,2'2," - 2 terpyridyl) to DNA, poly[d(G-C)] and poly[d(A-T)]...Full Text Available

1985-09-11

365

The development of an integrated multistaged fluid bed retorting process. Annual report, October 1, 1992--September 30, 1993  

Energy Technology Data Exchange (ETDEWEB)

This report summarizes the progress made on the development of an integrated multistage fluidized bed retorting process (KENTORT II) during the period of October 1, 1992 through September 30, 1993 under Cooperative Agreement No. DE-FC21-90MC27286 with the Morgantown Energy Technology Center, US Department of Energy. The KENTORT II process includes integral fluidized bed zones for pyrolysis, gasification, and combustion of the oil shale. The purpose of this program is to design and test the KENTORT II process at the 50-lb/hr scale. The PDU was assembled, instrumented and tested during this fiscal year. Along with the major activity of commissioning the 50-lb/hr retort, work was also completed in other areas. Basic studies of the cracking and coking kinetics of model compounds in a fixed bed reactor were continued. Additionally, as part of the effort to investigate niche market applications for KENTORT ...

1993-11-01

366

The Outermost Ejecta of Type Ia Supernovae  

CERN Document Server

The properties of the highest velocity ejecta of normal Type Ia supernovae (SNe Ia) are studied via models of very early optical spectra of 6 SNe. At epochs earlier than 1 week before maximum, SNe with a rapidly evolving Si II 6355 line velocity (HVG) have a larger photospheric velocity than SNe with a slowly evolving Si II 6355 line velocity (LVG). Since the two groups have comparable luminosities, the temperature at the photosphere is higher in LVG SNe. This explains the different overall spectral appearance of HVG and LVG SNe. However, the variation of the Ca II and Si II absorptions at the highest velocities (v >~ 20,000 km/s) suggests that additional factors, such as asphericity or different abundances in the progenitor white dwarf, affect the outermost layers. The C II 6578 line is marginally detected in 3 LVG SNe, suggesting that LVG undergo less intense burning. The ...

2007-01-01

367

Silver(I), mercury(II) and palladium(II) complexes of functionalized N-heterocyclic carbenes: Synthesis, structural studies and catalytic activity  

British Library Electronic Table of Contents (United Kingdom)

A series of NHC silver(I), mercury(II) and palladium(II) complexes, [(1,3-diethylbimy)6Ag4I3]I (2), [(1-benzyl-3-picolylbimy)Ag2Br2]n (3), [(1-benzyl-3-picolylbimy)HgI(CH2CN)]2 (4), {[(1-picolyl-3-npropylbimy)2Hg][Hg2I6]}n (5) and [(1,3-dipicolylbimy)PdCl]Cl (6), as well as one anionic complex [1,3-diethylbimidazolium]2[HgI4] (1) (bimy=benzimidazol-2-ylidene), have been prepared and characterized. Interestingly, a wind wheel-like Ag4I3 arrangement in 2 is formed, 1D polymeric chain containing 12-membered macrometallocycles and quadrangle Ag2Br2 units in 3 is generated, and the a-carbon atom of deprotonated acetonitrile ([CH2CN]-) in 4 participates in coordination with mercury(II) atom. In the crystal packings of complexes 1-6, 2D supramolecular layers or 3D supramolecular architectures are...

2011-01-01

368

Redox reactions of Cu(II)-amine complexes in aqueous solutions  

Energy Technology Data Exchange (ETDEWEB)

A number of amines can be employed for all volatile treatment (AVT) of steam generator (SG) systems of nuclear power reactors. These amines form complexes with Cu{sup 2+} and Ni{sup 2+} ions which come into water due to corrosion. The redox reactions of a number of Cu(II)-AVT amine complexes and the stability of the transient species formed have been studied by pulse radiolysis technique. Rate constants for the reaction of e{sub aq}{sup -} with a number of Cu(II)-amine complexes have been determined by following the decay of e{sub aq}{sup -} absorption. Stability of Cu(I)-amine complexes was studied by following the kinetics of the bleaching signal formed at the {lambda}{sub max} of the Cu(II) amine complex. Except for Cu(I)-triethanolamine complex all other Cu(I)-amine complexes were found to be stable. One-electron oxidation of Cu(II) amine complexes was studied using azidyl radicals for the oxidation ...

2003-03-01

369

Origin and spread of a common deletion causing mucolipidosis type II: insights from patterns of haplotypic diversity  

British Library Electronic Table of Contents (United Kingdom)

Coutinho MF, Encarnao M, Gomes R, da Silva Santos L, Martins S, Sirois-Gagnon D, Bargal R, Filocamo M, Raas-Rothschild A, Tappino B, Laprise C, Cury GK, Schwartz IV, Artigals O, Prata MJ, Alves S. Origin and spread of a common deletion causing mucolipidosis type II: insights from patterns of haplotypic diversity. Mucolipidosis II (ML II alpha/beta), or I-cell disease, is a rare genetic disease in which activity of the uridine diphosphate (UDP)-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-phosphotransferase) is absent. GlcNAc-phosphotransferase is a multimeric enzyme encoded by two genes, GNPTAB and GNPTG. A spectrum of mutations in GNPTAB has been recently reported to cause ML II alpha/beta. Most of these mutations were found to be private or rare. ...

2011-01-01

370

Localized tachyons in C{sup 3}/Z{sub N}  

Energy Technology Data Exchange (ETDEWEB)

We study the condensation of localized closed string tachyons in C{sup 3}/Z{sub N} non-supersymmetric noncompact orbifold singularities via renormalization group flows that preserve supersymmetry in the worldsheet conformal field theory and their interrelations with the toric geometry of these orbifolds. We show that for worldsheet supersymmetric tachyons, the endpoint of tachyon condensation generically includes 'geometric' terminal singularities (orbifolds that do not have any marginal or relevant Kahler blowup modes) as well as singularities in co-dimension two. Some of the various possible distinct geometric resolutions are related by flip transitions. For Type II theories, we show that the residual singularities that arise under tachyon condensation in various classes of Type II theories also admit a Type II GSO projection. We further show that Type II orbifolds entirely devoid of ...

2004-08-01

371

Expression of cyclin D{sub 1} during endotoxin-induced aleveolar type II cell hyperplasia in rat lung and the detection of apoptotic cells during the remodeling process  

Energy Technology Data Exchange (ETDEWEB)

Our studies have shown that endotoxin intratracheally instilled into the rat lung induces proliferation of alveolar type II cells. In that study, the alveolar type II cells. In that study, the alveolar type II cell hyperplasia occurred 2 d after instillation of endotoxin and persisted for a further 2 d. After hyperplasia, the lung remodeled and returned to a normal state within 24-48 h. Understanding the mechanisms involved in the remodeling process of this transient hyperplasia may be useful to identify molecular changes that are altered in neoplasia. The purpose of the present study was to corroborate induction of epithelial cell hyperplasia by endotoxin and to delineate mechanisms involved in tissue remodeling after endotoxin-induced alveolar type II cell hyperplasia. In conclusion, immonostaining with cyclin D1 and cytokeratin shows that endotoxin induced epithelial cell proliferation and resulted ...

1995-12-01

372

Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22  

Energy Technology Data Exchange (ETDEWEB)

Two overlapping cDNA clones encoding human DNA topoisomerase II were identified by two independent methods. In one, a human cDNA library in phage {lambda} was screened by hybridization with a mixed oligonucleotide probe encoding a stretch of seven amino acids found in yeast and Drosophila DNA topoisomerase II; in the other, a different human cDNA library in a {lambda}gt11 expression vector was screened for the expression of antigenic determinants that are recognized by rabbit antibodies specific to human DNA topoisomerase II. The entire coding sequences of the human DNA topoisomerase II gene were determined from these and several additional clones, identified through the use of the cloned human TOP2 gene sequences as probes. Hybridization between the cloned sequences and mRNA and genomic DNA indicates that the human enzyme is encoded by a single-copy gene. The location of the gene was mapped to ...

1988-10-01

373

Biosorption of copper (II) onto immobilized cells of Pycnoporus sanguineus from aqueous solution: Equilibrium and kinetic studies  

Energy Technology Data Exchange (ETDEWEB)

The ability of white-rot fungus, Pycnoporus sanguineus to adsorb copper (II) ions from aqueous solution is investigated in a batch system. The live fungus cells were immobilized into Ca-alginate gel to study the influence of pH, initial metal ions concentration, biomass loading and temperature on the biosorption capacity. The optimum uptake of Cu (II) ions was observed at pH 5 with a value of 2.76 mg/g. Biosorption equilibrium data were best described by Langmuir isotherm model followed by Redlich-Peterson and Freundlich models, respectively. The biosorption kinetics followed the pseudo-second order and intraparticle diffusion equations. The thermodynamic parameters enthalpy change (10.16 kJ/mol) and entropy change (33.78 J/mol K) were determined from the biosorption equilibrium data. The FTIR analysis showed that -OH, -NH, C-H, C=O, -COOH and C-N groups were involved in the biosorption of Cu (II) ions onto immobilized ...

2009-01-15

374

The effect of a sports chiropractic manual therapy intervention on the prevention of back pain, hamstring and lower limb injuries in semi-elite Australian Rules footballers: a randomized controlled trial  

UK PubMed Central (United Kingdom)

BackgroundHamstring injuries are the most common injury in Australian Rules football. It was the aims to investigate whether a sports chiropractic manual therapy intervention protocol...Full Text Available

375

The Risk of Paradoxical Embolism (RoPE) Study: Developing risk models for application to ongoing randomized trials of percutaneous patent foramen ovale closure for cryptogenic stroke  

UK PubMed Central (United Kingdom)

BackgroundDespite the diffusion into practice of percutaneous closure of a patent foramen ovale (PFO) in patients with cryptogenic stroke (CS), the benefits have not been demonstrated,...Full Text Available

376

The Effect of Circumcision of HIV-Infected Men on Human Papillomavirus Infection in Female Partners: Analyses Using Data from a Randomized Trial in Rakai, Uganda  

UK PubMed Central (United Kingdom)

BackgroundMale circumcision (MC) reduces high-risk human papillomavirus (HR-HPV) in HIV-uninfected men and their female partners. We assessed whether MC of HIV-infected...Full Text Available

2011-08-01

377

Stein method for invariant measures of diffusions via Malliavin calculus  

CERN Document Server

Given a random variable $F$ regular enough in the sense of the Malliavin calculus, we are able to measure the distance between its law and almost any continuous probability law on the real line. The bounds are given in terms of the Malliavin derivative of $F$. Our approach is based on the theory of It\\^o diffusions and the stochastic calculus of variations. Several examples are considered in order to illustrate our general results.

2011-01-01

378

Spectral properties of cylindrical quasioptical cavity resonator with random inhomogeneous side boundary.  

Science.gov (United States)

A rigorous solution for the spectrum of a quasioptical cylindrical cavity resonator with a randomly rough side boundary has been obtained. To accomplish this task, we have developed a method for the separation of variables in a wave equation, which enables one, in principle, to rigorously examine any limiting case-from negligibly weak to arbitrarily strong disorder at the resonator boundary. It is shown that the effect of disorder-induced scattering can be properly described in terms of two geometric potentials, specifically, the "amplitude" and the "gradient" potentials, which appear in wave equations in the course of conformal smoothing of the resonator boundaries. The scattering resulting from the gradient potential appears to be dominant, and its impact on the whole spectrum is governed by the unique sharpness parameter ?, the mean tangent of the asperity slope. As opposed to the resonator with bulk disorder, the distribution of nearest-neighbor spacings (NNS) ...

2011-08-30

379

Sequence and Organization of pXO1, the Large Bacillus anthracis Plasmid Harboring the Anthrax Toxin Genes  

UK PubMed Central (United Kingdom)

The Bacillus anthracis Sterne plasmid pXO1 was sequenced by random, “shotgun” cloning. A circular sequence of 181,654 bp was generated. One hundred forty-three open...Full Text Available

1999-10-01

380

Re-inventing Willis  

British Library Electronic Table of Contents (United Kingdom)

Scientists often re-invent things that were long known. Here we review these activities as related to the mechanism of producing power law distributions, originally proposed in 1922 by Yule to explain experimental data on the sizes of biological genera, collected by Willis. We also review the history of re-invention of closely related branching processes, random graphs and coagulation models.

2011-01-01

381

Powder composites for gas-plasma ceramic coatings  

Energy Technology Data Exchange (ETDEWEB)

The method of production of xAl{sub 2}O{sub 3}-yTiO{sub 2} compositions provides for the depth distribution of coating components and specifies its mechanical properties. In case of the composition obtained by cladding, titanium is mainly concentrated at the substrate. In case of mechanical mixture or composition obtained by sintering the oxides, the depth distribution of coating components is random.

1995-12-31

382

Partially-carbonized polyacrylonitrile filter  

Energy Technology Data Exchange (ETDEWEB)

A filter for extracting solids and liquids from gaseous combustion exhausts comprises a textile filter element formed of polyacrylonitrile fibers oxidized by careful heat treatment and comprising approximately 61% carbon after treatment. The filter may be woven, knitted or formed as a batting of randomly-oriented fibers. Abrasion resistant coatings and lubricants for the fibers are disclosed. The filter material is especially useful as a filter bag.

1984-04-24

383

Pairing correlation effects on the electron-scattering form factor of the 1/sup +/ state at 3. 486 MeV in /sub 38//sup 88/Sr/sub 50/  

Energy Technology Data Exchange (ETDEWEB)

The electron scattering form factor for excitation of the 1/sup +/ state of /sup 88/Sr at 3.486 MeV has been calculated in the quasiparticle random phase approximation (QRPA). The disagreement between the data and restricted shell-model calculations can be explained in terms of the pairing correlations introduced by the QRPA; no ..delta..-h admixtures are required.

1985-06-06

384

Pairing correlation effects on the electron-scattering form factor of the 1"+ state at 3.486 MeV in _3_8"8"8Sr_5_0  

International Nuclear Information System (INIS)

The electron scattering form factor for excitation of the 1"+ state of "8"8Sr at 3.486 MeV has been calculated in the quasiparticle random phase approximation (QRPA). The disagreement between the data and restricted shell-model calculations can be explained in terms of the pairing correlations introduced by the QRPA; no #DELTA#-h admixtures are required. (orig.).

385

Numerical simulation of VAWT stochastic aerodynamic loads produced by atmospheric turbauence: VAWT-SAL code  

Energy Technology Data Exchange (ETDEWEB)

Blade fatigue life is an important element in determining the economic viability of the Vertical-Axis Wind Turbine (VAWT). A principal source of blade fatigue is thought to be the stochastic (i.e., random) aerodynamic loads created by atmospheric turbulence. This report describes the theoretical background of the VAWT Stochastic Aerodynamic Loads (VAWT-SAL) computer code, whose purpose is to numerically simulate these random loads, given the rotor geometry, operating conditions, and assumed turbulence properties. A Double-Multiple-Stream Tube (DMST) analysis is employed to model the rotor's aerodynamic response. The analysis includes the effects of Reynolds number variations, different airfoil sections and chord lengths along the blade span, and an empirical model for dynamic stall effects. The mean ambient wind is assumed to have a shear profile which is described by either a power law or a logarithmic variation with height above ...

1991-09-01

386

Intermittency and the central limit theorem  

Energy Technology Data Exchange (ETDEWEB)

Central limit theorem estimates of anomalous fractal dimensions of self-similar random cascades are studied. It is found that, in general, the normal approximation fails badly. A systematic series of approximations which converges to the exact result (both for the fractal dimensions and for the distribution itself) is derived for the {alpha}-model. Consequences for the 'empty bin effect' are indicated. (orig.).

1991-04-01

387

Grain boundaries structure and mechanical properties of aluminium alloys  

Energy Technology Data Exchange (ETDEWEB)

The paper discusses the problem of influence of grain boundaries structure on mechanical properties of aluminium alloys at elevated temperatures. Showed the data amount of grain boundaries close to special and a random of grain boundaries. The results of calculation of contribution of different mechanisms of deformation to the total deformation for alloys with different types of grain boundaries are given. (orig.)

1996-08-01

388

Frailty Models in Survival Analysis  

CERN Document Server

The concept of frailty offers a convenient way to introduce unobserved heterogeneity and associations into models for survival data. In its simplest form, frailty is an unobserved random proportionality factor that modifies the hazard function of an individual or a group of related individuals. "Frailty Models in Survival Analysis" presents a comprehensive overview of the fundamental approaches in the area of frailty models. The book extensively explores how univariate frailty models can represent unobserved heterogeneity. It also emphasizes correlated frailty models as extensions of

2010-01-01

389

Effectiveness of a school-based physical activity-related injury prevention program on risk behavior and neuromotor fitness a cluster randomized controlled trial  

UK PubMed Central (United Kingdom)

BackgroundTo investigate the effects of a school-based physical activity-related injury prevention program, called 'iPlay', on risk behavior and neuromotor fitness.MethodsIn...Full Text Available

390

Does Sex Matter? Thirty-Day Stroke and Death Rates Following Carotid Artery Stenting in Women vs. Men: Results from the Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST) Lead-in Phase  

UK PubMed Central (United Kingdom)

BACKGROUNDSeveral carotid endarterectomy (CEA) randomized controlled trials (RCTs) and series have reported higher perioperative stroke and death rates for women...Full Text Available

2009-04-01

391

Comparable Postprandial Glucose Reductions with Viscous Fiber Blend Enriched Biscuits in Healthy Subjects and Patients with Diabetes Mellitus: Acute Randomized Controlled Clinical Trial  

UK PubMed Central (United Kingdom)

AimTo compare the blood glucose-lowering effect of a highly viscous fiber blend (VFB) added to a starchy snack on postprandial glycemia between healthy participants and participants...Full Text Available

2008-12-01

392

Bilby distribution and fire: a test of alternative models of habitat suitability in the Tanami Desert, Australia  

British Library Electronic Table of Contents (United Kingdom)

The distribution of the bilby Macrotis lagotis was assessed in the Tanami Desert using stratified random plots, repetitively sampled transects, aerial survey transects, and ground truth plots. Compared to a previous assessment of distribution, the extent of occurrence has changed little in the last 20 yr. However, the area of occupancy is small relative to the extent of occurrence and

2007-01-01

393
394

Amp-PCR: Combining a Random Unbiased Phi29-Amplification with a Specific Real-Time PCR, Performed in One Tube to Increase PCR Sensitivity  

UK PubMed Central (United Kingdom)

In clinical situations where a diagnostic real-time PCR assay is not sensitive enough, leading to low or falsely negative results, or where detection earlier in a disease progression would benefit the...Full Text Available

395

A Randomized Trial Assessing the Safety and Immunogenicity of AS01 and AS02 Adjuvanted RTS,S Malaria Vaccine Candidates in Children in Gabon  

UK PubMed Central (United Kingdom)

BackgroundThe malaria vaccine candidate antigen RTS,S includes parts of the pre-erythrocytic stage circumsporozoite protein fused to the Hepatitis B surface antigen. Two Adjuvant...Full Text Available

396

Improvements in SISCOM II technology; Introduccion de Mejoras Tecnologicas en el SISCOM II  

Energy Technology Data Exchange (ETDEWEB)

This document is the Final Report for the project Introduccion de Mejoras Tecnologicas en el SISCOM II, or Improvements in SISCOM II Technology. It consists of a brief description of the activities carried out during the project, and several Annexes that explain in a deeper way each result. SISCOM II is the main telemetry system currently in use in the Spanish underground coal mining, but it was developed ten years ago and needed a technological update, which was the objective of this project. The aims of the project were: To develop Hardware and Software for the Out stations currently used (maintenance developments) To design new hardware and software, easier to use in the current and new applications of SISCOM II Both objectives were met, although not in the way originally intended. The main results were: In the field of old Out stations update: A new set of boards for the old Out stations was ...

2000-07-01

397

Difference in prognostic factors between stage IB and II uterine cervical carcinoma patients treated with radical hysterectomy and postoperative radiation therapy  

International Nuclear Information System (INIS)

The purpose of the current study was to evaluate the difference in prognostic factors between stage IB and II uterine cervical carcinoma patients treated with postoperative radiation therapy. Between May 1988 and May 1998, a total of 94 patients including 47 patients with stage IB and 47 patients with stage II uterine cervical carcinoma were treated with postoperative radiation therapy at Tokyo Metropolitan Komagome Hospital. All patients were treated with 10 MV X-rays using an anterior-posterior parallel opposed field which covered the whole pelvis. Fractionation was 2 Gy per day, five fractions per week, to a total dose of 50 Gy. The 5-year overall survival rates of stage IB and II were 89.4% and 79.3%, respectively. In multivariate analysis for all patients, lymph node status, histology, and surgical margin status were recognized as prognostic factors. Limited to stage IB patients, lymph node status was the only ...

398

The CDF II eXtremely Fast Tracker Upgrade  

International Nuclear Information System (INIS)

The CDF II eXtremely Fast Tracker (XFT) is the trigger processor which reconstructs charged particle tracks in the CDF II central outer tracking chamber. The XFT tracks are also extrapolated to the electromagnetic calorimeter and muon chambers and are associated to electromagnetic clusters and muon stubs to generate trigger electron and muon candidates. The steady increase of the Tevatron instantaneous luminosity and the resulting higher occupancy of the chamber demanded an upgrade of the original system, which performed tracking only in the transverse plane of the chamber and was consequently affected by a significant level of fake tracks. In the upgraded XFT, tracking is reinforced by using additional data from the stereo layers of the chamber to reduce the level of fake tracks and to perform three-dimensional track reconstruction. A review of this upgrade is presented.

2007-10-21

399

Technical design aspects of Feasibility Study-II  

Energy Technology Data Exchange (ETDEWEB)

Feasibility Study-II examined a high-performance Neutrino Factory providing 1 x 10{sup 20} neutrinos per year aimed at a long-baseline detector. The Study was sponsored jointly by BNL and the Neutrino Factory and Muon Collider Collaboration ration (MC) and is based on a 1 MW proton driver operating at 24 GeV, i.e., an upgraded version of the AGS accelerator. Compared with the earlier FNAL-sponsored study (Feasibility Study-I), there is a sixfold improvement in performance. Here we describe details of the implementation of Study-II concepts and discuss their efficacy. Alternative approaches that will be pursued in follow-on R and D activities are also described briefly.

2001-08-15

400

Some thoughts on the mechanism of cellular trapping of Cu(II)-ATSM  

British Library Electronic Table of Contents (United Kingdom)

Cu(II)-ATSM continues to be investigated, both in the laboratory and in the clinic, as a tumor hypoxia imaging agent. However, meaningful interpretation of these images requires a more complete understanding of the mechanism by which the tracer is trapped within the cell. Cu(II)-ATSM is a simple molecule and its biochemical interaction with cells is similarly simple, mainly based upon redox chemistry. Here we suggest that the trapping mechanism is biphasic. The first phase is a reduction/oxidation cycle involving thiols and molecular oxygen. This can be followed by interaction with proteins in the mitochondria leading to more permanent retention of the tracer. The uptake mechanism is complicated by this second step because of the changes in the cell resulting from hypoxia, such as an incre...

2010-01-01

401

Physicochemical investigation of the behavior of elements in chloride melts in the presence of solid phases based on phosphates of polyvalent elements. II. Behavior of strontium and barium  

Energy Technology Data Exchange (ETDEWEB)

The distribution of the alkaline earth elements strontium and barium between the solid phases of phosphates of transition elements of group 4 and chloride melts was studied. The distribution coefficients of strontium and barium were found at T = 700-800/sup 0/C. Phosphates of the type NaM/sub 2//sup (IV)/(PO/sub 4/)/sub 3/, where M/sub (IV)/ represents titanium, zirconium, and hafnium, were used as the solid phases. It was established that there is an enrichment of the precipitates with the distributed components. The distribution coefficient depends on the nature of the solid phase and the temperature. It was suggested that M/sup (II)/ x M/sub 4//sup (IV)/(PO/sub 4/)/sub 6/ is formed in processes of distribution, where M/sup (II)/ represents Sr, Ba.

1987-07-01

402

New High-Pressure Excitations in Parahydrogen  

Energy Technology Data Exchange (ETDEWEB)

Raman and infrared spectroscopy of para-H{sub 2} to pressures in excess of 200GPa and to 8K using new ultrapure synthetic diamond anvils reveals numerous new vibrational excitations in the three high-pressure phases. Highly resolved Raman-active librons indicate differences in orientational ordering between phasesII and III, including evidence for changes within phaseII. The librons in phaseIII are strongly pressure dependent and reflect a substantial increase in ordering with pressure. Multiple vibrons in all three phases (I, II, and III) are observed. The results place new bounds on predicted crystal structures and dynamics of the dense molecular solid. {copyright} {ital 1997} {ital The American Physical Society}

1998-01-01

403

Molecular structure of platinum(III) hydroxoacetates according to data from EXAFS spectra  

Energy Technology Data Exchange (ETDEWEB)

The EXAFS spectra of the platinum(III) complexes Pt/sub 4/(OAc)/sub 10/(OH)/sub 2/ (I) and Pt/sub 4/ (OAc)/sub 4/(OH)/sub 8/(H/sub 2/O)/sub 2/ (II) have been investigated. It has been found by a curve-fitting method and with the aid of Fourier transformations that the shortest Pt-Pt distances are 2.61 A in complex I and 2.36 and 2.6 A in II. The values of the bond lengths obtained are consistent with the molecular structures proposed for complexes I and II, which contain skeletons of four platinum atoms in the form of a square or a rectangle, as well as with the known literature data on the lengths of Pt-Pt bonds in Pt(III) complexes.

1986-04-01

404

Effects of retinoic acid on maturation of immature mouse oocytes in the presence and absence of a granulosa cell co-culture system  

British Library Electronic Table of Contents (United Kingdom)

Purpose Evaluation of the all-trans retinoic acid (t-RA) effects on in vitro maturation (IVM) and in vitro fertilization (IVF) of immature mouse oocytes in the presence and absence of granulosa cell monolayer. Methods Denuded oocytes isolated from mice ovaries and matured in IVM medium alone (Control I), IVM medium in the presence of granulosa cells (Control II), IVM medium with t-RA (Experimental I) and IVM medium simultaneously with t-RA and granulosa cells (Experimental II). After 24?h, matured oocytes were fertilized in T6 medium and their development was followed until the blastocyst stage. Metaphase II oocytes ploidy were evaluated by chromosome counting. Results The t-RA group compared to the control groups showed no obvious abnormalities. Additionally maturation and embryo developm...

2011-01-01

405

Chromatography of metal ions with a triazine chelating resin  

International Nuclear Information System (INIS)

The synthesis, characterization, and some analytical applications of a new triazine resin are described. Separation of group IB, IIB, VIB, and VIIB metal ions from group VIII metal ions is achieved by this PDT-4 resin. Calcium(II) and magnesium(II) are taken up at pH = 6, 0.1 M acetate and are eluted at pH = 6, 0.1 M sodium nitrate. Copper(II) is retained at pH = 6, 0.1 M acetate and pH = 1 hydrochloric acid and is eluted subsequently by 5 M perchloric acid. Molybdenum(VI) is sorbed selectively from 0.1 N sulfuric acid or hydrochloric acid and is eluted in a tight band by 0.1 N sodium hydroxide. Numerous rapid column chromatographic separations are reported using this new resin, including analysis of NBS standard samples.

406

Chiral Rings, Mirror Symmetry and the Fate of Localized Tachyons  

Energy Technology Data Exchange (ETDEWEB)

We study the localized tachyon condensation of non-supersymmetric orbifold backgrounds in their mirror Landau-Ginzburg picture. We first show that the R-charges of chiral primaries increase under the process of condensing the tachyon in the same chiral ring. Then, utilizing the existence of four copies of (2,2) worldsheet supersymmetry, we show that the minimal tachyon mass in twisted sectors increases in CFT and type 0 string and it plays the role of the c-function of the twisted sectors. We also study the GSO projection in detail and show that type II decays to only to type II while type 0 can mix with type 0 and II under the RG-flow.

2003-03-20

407

A phase II trial of sorafenib in first-line metastatic urothelial cancer: a study of the PMH Phase II Consortium  

British Library Electronic Table of Contents (United Kingdom)

Summary Background Sorafenib is an oral multikinase inhibitor that blocks cell proliferation via the ERK pathway and angiogenesis via the VEGF pathway. This phase II trial was conducted to determine the efficacy and tolerability of sorafenib for the treatment of patients with metastatic urothelial cancer (UC) who had not had prior chemotherapy for advanced disease. Patients and Methods Seventeen chemo-na?ve UC patients with adequate performance status and organ function were treated with sorafenib 400?mg twice daily on a continuous basis until progression or unacceptable toxicity. The primary endpoint was objective tumor response rate as measured by RECIST criteria. Secondary endpoints included rate of prolonged stable disease (>3?months), time to progression, median and 1?yr survival and ...

2011-01-01

408

A computational approach to the electronic and optical properties of Ru(II) and Ir(III) polypyridyl complexes: Applications to DSC, OLED and NLO  

British Library Electronic Table of Contents (United Kingdom)

Ruthenium(II) and Iridium(III) polypyridyl complexes have been intensively investigated due to their use in energy conversion and light-emitting devices and materials for non-linear optics. Quantum mechanical computer simulations of molecules and materials have become increasingly popular in the scientific community. Along with experimental investigations, such computational analyses can provide complementary information on the electronic and optical properties of transition metal compounds of interest for optoelectronic applications. Here, we provide a unified review of recent work carried out on computational investigations of a large series of Ruthenium(II) and Iridium(III) polypyridyl complexes, discussing the relations between their electronic structure and optical properties and thei...

2011-01-01

409

X-ray structure of sensory rhodopsin II at 2.1-? resolution  

UK PubMed Central (United Kingdom)

Sensory rhodopsins (SRs) belong to a subfamily of heptahelical transmembrane proteins containing a retinal chromophore. These photoreceptors mediate the cascade of vision in animal eyes and phototaxis...Full Text Available

2001-08-28

410

Wounding Nicotiana tabacum Leaves Causes a Decline in Endogenous Indole-3-Acetic Acid 1  

UK PubMed Central (United Kingdom)

We have previously observed that auxin can act as a repressor of the wound-inducible activation of a chimeric potato proteinase inhibitor II-CAT chimeric gene (pin2-CAT) in transgenic...Full Text Available

1991-07-01

411

Variants within the yeast Ty sequence family encode a class of structurally conserved proteins.  

UK PubMed Central (United Kingdom)

The Ty transposable elements of Saccharomyces cerevisiae form a heterogeneous family within which two broad structural classes (I and II) exist. The two classes differ by two large substitutions and...Full Text Available

1985-06-11

412

Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogaster  

UK PubMed Central (United Kingdom)

Molecular Misreading (MM) is the inaccurate conversion of genomic information into aberrant proteins. For example, when RNA polymerase II transcribes a GAGAG motif it synthesizes at low frequency RNA...Full Text Available

413

US EPA, Consumer Labeling Initiative Phase II Report  

Science.gov (United States)

... NE Mall Room B-607, EPA Headquarters, 401 M ... formally adopted and initiated a joint strategy for ... CLI kick-off Partner and Task Force meeting. ...

2008-10-07

414

Trans-Species Polymorphism and Selection in the MHC Class II DRA Genes of Domestic Sheep  

UK PubMed Central (United Kingdom)

Highly polymorphic genes with central roles in lymphocyte mediated immune surveillance are grouped together in the major histocompatibility complex (MHC) in higher vertebrates. Generally, across vertebrate...Full Text Available

415

Thin Film Solar Cells and Solar Cell Testing, Volume II Proceedings of the Fourth Photovoltaic Specialists Conference  

Science.gov (United States)

Thin film solar cells and solar cell testing - photovoltaic cells, radiation damage to cadmium sulfide solar cells, and airplane testing of solar cells

1964-01-01

416

Theoretical Models and Operational Frameworks in Public Health Ethics  

UK PubMed Central (United Kingdom)

The article is divided into three sections: (i) an overview of the main ethical models in public health (theoretical foundations); (ii) a summary of several published frameworks for public health ethics...Full Text Available

2010-01-01

417

The effect of lipopolysaccharide on bovine mammary macrophage function.  

UK PubMed Central (United Kingdom)

The effect of Escherichia coli lipopolysaccharide (LPS) on the expression of major histocompatibility complex (MHC) class II molecules by bovine mammary macrophages was examined. The ability of LPS-treated...Full Text Available

1991-07-01

418

The Sorcerer II Global Ocean Sampling Expedition: Northwest Atlantic through Eastern Tropical Pacific  

UK PubMed Central (United Kingdom)

The world's oceans contain a complex mixture of micro-organisms that are for the most part, uncharacterized both genetically and biochemically. We report here a metagenomic study of the marine planktonic...Full Text Available

2007-03-01

419

The Clinical Value of PET with Amino Acid Tracers for Gliomas WHO Grade II  

UK PubMed Central (United Kingdom)

The clinical management of adults with low-grade gliomas (LGGs) remains a challenge. There is no curative treatment, and management of individual patients is a matter of deciding optimal timing as well...Full Text Available

2011-01-01

420

Tarantula Huwentoxin-IV Inhibits Neuronal Sodium Channels by Binding to Receptor Site 4 and Trapping the Domain II Voltage Sensor in the Closed Configuration*S?  

UK PubMed Central (United Kingdom)

Peptide toxins with high affinity, divergent pharmacological functions, and isoform-specific selectivity are powerful tools for investigating the structure-function relationships of voltage-gated...Full Text Available

2008-10-03

421

THEMIS-D - SPASE Resource Description  

Science.gov (United States)

Feb 23, 2011 ... THEMIS-D: The Solid State Telescope (SST) measures the incoming ... Each single sensor covers an angle of 36 degrees. .... The five small satellites were launched together on a Delta II rocket and they carry identical ...

422

Syntheses, characterizations and structures of NO donor Schiff base ligands and nickel(II) and copper(II) complexes  

British Library Electronic Table of Contents (United Kingdom)

New Schiff base derivatives (L1 and L2) were prepared by the condensation of 2-hydroxy-3-methoxybenzaldehyde (o-vanillin) and 3-hydroxy-4-methoxybenzaldehyde (iso-vanillin) with 5-methylfurfurylamine. Two new complexes [Ni(L1)2] and [Cu(L1)2] have been synthesized with bidentate NO donor Schiff base ligand (L1). The Ni(II) and Cu(II) atoms in each complex are four coordinated in a square planar geometry. Schiff bases (L1 and L2) and complexes [Ni(L1)2] and [Cu(L1)2] were characterized by elemental analyses, FT-IR, UV-vis, mass and 1H, 13C NMR spectroscopies. The crystal structures of the ligand (L2) and complexes [Ni(L1)2] and [Cu(L1)2] have also been determined by using X-ray crystallographic technique.

2011-01-01

423

Subject Index to MIL-HDBK-338 Electronic Reliability Design ...  

Science.gov (United States)

... CONDUCTOR 11,5-209 CAPACITORS II,A-2, 11,5-144 ALTITUDE EFFECTS 11,5-160 ALUMINUM ELECTROLYTIC CAPACITORS 11,5-145 ...

2011-05-14

424

Structure determination and investigation on cytotoxicity of potassium dichlorido(l-prolinato)platinate(II) versus chlorido(dimethyl sulfoxide)(l-prolinato)platinum(II) complex -In vitro antitumor deactivation by Cl^-/dmso ligand exchange  

British Library Electronic Table of Contents (United Kingdom)

Potassium dichlorido(l-prolinato)platinate(II), K[PtCl"2(l-pro"?"H)] (1), and chlorido(dimethyl sulfoxide)(l-prolinato)platinum(II), [PtCl(l-pro"?"H)(dmso)] (2), were synthesized by ligand substitution reactions. Both complexes were characterized by ^1H, ^1^3C, and ^1^9^5Pt NMR spectroscopy, elemental analysis, and HR-ESI-MS. The molecular structures of 1 and 2 were determined by single crystal X-ray diffraction, proving bidentate coordinated l-prolinato ligand and SP-4-4 configuration of 2a. With the help of DFT calculations stability of possible isomers of 1 and 2 was studied. A considerable difference in the in vitro cytotoxicity of 1 versus 2a (exchange of one chlorido ligand by dmso) against four human cancer cell lines was found.

2011-01-01

425

Structural aberrations in group A Staphylococcus bacteriophages.  

UK PubMed Central (United Kingdom)

Six related Staphylococcus phages spontaneously produced various abnormal head and tail structures: (i) giant capsids which were tailed and apparently contained nucleic acid; (ii) regular and irregular...Full Text Available

1976-05-01

426

Strength training for wheelchair users.  

UK PubMed Central (United Kingdom)

Sedentary adult males with spinal lesions, all habitual wheelchair users, were allocated to exercise (n = 11) and control (n = 4) groups. A Cybex II dynamometer was used to assess peak power, average...Full Text Available

1990-03-01

427

Stereospecific ligands and their complexes. Part VII. Synthesis, characterization and in vitro antitumoral activity of platinum(II) complexes with O,Oprime-dialkyl esters of (S,S)-ethylenediamine-N,Nprime-di-2-(4-methyl)pentanoic acid  

British Library Electronic Table of Contents (United Kingdom)

Platinum(II) complexes (1-4) with bidentate N,Nprime-ligands, O,Oprime-dialkyl esters (alkyl = ethyl, n-propyl, n-butyl and n-pentyl), of (S,S)-ethylenediamine-N,Nprime-di-2-(4-methyl)pentanoic acid were synthesized and characterized by IR, 1H NMR and 13C NMR spectroscopy and elemental analysis. DFT calculations were performed for the complexes and it was found that only one diastereoisomer could be formed. Cytotoxic activity of complexes 1-4 was determined against chronic lymphocytic leukemia cells (CLL) and compared to the activity of ligand precursors L12HCl-L42HCl and corresponding palladium(II) complexes, [PdCl2L] (L = L1-L4). The complexes were found to exhibit significantly higher antitumor activities than cisplatin on CLL cells. Cytotoxic effect of platinum(II) complexes on CLL cel...

2011-01-01

428

Spectrophotometry of H II regions in the spiral galaxy M101  

Energy Technology Data Exchange (ETDEWEB)

Spectral line intensity data are presented for ionized hydrogen regions in the giant spiral galaxy M101. The influence of interstellar extinction is assessed and electron temperatures of the gas clouds are derived.

1981-04-01

429

Spectrophotometric determination of titanium and iron-application to Cherat volcanic ash, N.W.F.P  

International Nuclear Information System (INIS)

A rapid and sensitive method for the separation and determination of titanium and iron in thiocyanate system has been developed. The extractability of Ti(II) by high molecular weight (HMWA) in organic solvent (HCl/sub 3/) and its separation from Fe(III) was examined. The yellow coloured complex of Ti(II)-SCN in quantitatively extracted into the organic phase containing tribenzyl tribenzylamine (TBA) - a high molecular weight amine, whereas the blood red coloured complex of Fe(III)-SCN formed under the same conditions get separated in the aqueous phase. On the basis of the selective extractability, a method has been developed for the separation as well as simultaneous determination of Ti(II) and Fe(III) in presence of many other elements. The molar extinction coefficients were found to be 1.9 x 10/sup 5/ l mol/sup -1/ cm/sup -1/ and 1.11 x 10/sup 5/ l mol/sup -1/ cm/sup -1/ respectively for Ti(II) and ...

1998-08-01

430

Specific expression profile and prognostic significance of peroxiredoxins in grade II-IV astrocytic brain tumors  

UK PubMed Central (United Kingdom)

BackgroundPeroxiredoxins (Prxs) have recently been suggested to have a role in tumorigenesis.MethodsWe studied the expression of Prx I-VI and their...Full Text Available

431

SPASE Resource Description - the VMO - NASA  

Science.gov (United States)

THEMIS-A: The Solid State Telescope (SST) measures the incoming intensity ... units (heads), each SST unit has two pairs of opposing ion and electron sensors. .... The five small satellites were launched together on a Delta II rocket and they ...

432

SNQ for medical research  

Energy Technology Data Exchange (ETDEWEB)

The planned spallation source can be of considerable significance for biomedical basic research and for clinically relevant diagnostic and therapeutic applications. The following gives a brief description and explanations for its possible use in clinical medicine: I. Treatment of Malignant Tumors II. Production of Isotopes for Biochemical Investigations in Living Organisms for Diagnostic Purposes.

1984-12-01

433

Replication timing and transcriptional control: beyond cause and effect. Part II  

UK PubMed Central (United Kingdom)

SUMMARYReplication timing is frequently discussed superficially in terms of its relationship to transcriptional activity via chromatin structure. However, so little is known about...Full Text Available

2009-04-01

434

Remobilization of Tol2 transposons in Xenopus tropicalis  

UK PubMed Central (United Kingdom)

BackgroundThe Class II DNA transposons are mobile genetic elements that move DNA sequence from one position in the genome to another. We have previously demonstrated that the naturally...Full Text Available

435

Radon concentration measurement in dwellings in Belgrade  

International Nuclear Information System (INIS)

The results of the radon concentration measurements in dwellings in Belgrade were shown in this paper. The measurements were done using long term method with diffusion cups equipped with solid state nuclear track detector LR-115-II or CR-39. (author).

436

ROCK DEFORMATION. Final Progress Report  

Energy Technology Data Exchange (ETDEWEB)

The Gordon Research Conference (GRC) on ROCK DEFORMATION was held at II Ciocco from 5/19/02 thru 5/24/02. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.

2002-05-24

437

Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study  

UK PubMed Central (United Kingdom)

Human longevity is in part genetically determined, and the insulin/IGF-1 signal transduction (IIS) pathway has consistently been implicated. In humans, type 2 diabetes is a frequent disease that results...Full Text Available

438

Phase II Evaluation of Paclitaxel and Carboplatin in the Treatment of Carcinosarcoma of the Uterus: A Gynecologic Oncology Group Study  

UK PubMed Central (United Kingdom)

PurposePlatinum and taxane compounds have demonstrated activity in uterine carcinosarcoma (malignant mixed Mullerian tumor). Ifosfamide plus paclitaxel is the regimen with established...Full Text Available

2010-06-01

439

Perturbations of the Plebanski metric in general relativity. II. Perturbations of the fermion field.  

Science.gov (United States)

We obtain the radial Dirac equations for the Plebanski metric and transform these equations into one-dimensional wave equations. Finally we conclude with the result that the electron and the neutrino fields are not superradiant.

1986-09-01

440

Normandy Breakout: Strategic Decisions and Leadership Actions in Operations Goodwood and Cobra.  

Science.gov (United States)

Theoretically, the outcome of World War II in Europe hung in the balance as the Allies poured onto the Normandy beachhead. Following the June 6, 1944 invasion, the Allies continue to come ashore, massively building up men and material inside the beachhead...

2000-01-01

441

Nonlinear response of superconductors to alternating fields and currents  

Science.gov (United States)

This report discusses the following topics on superconductivity: nonlinearities in hard superconductors such as surface impedance of a type II superconductimg half space and harmonic generation and intermodulation due to alternating transport currents; and nonlinearities in superconducting weak links such as harmonic generation by a long Josephson Junction in a superconducting slab.

1997-10-08

442

Neutron stars in massive binary systems. I. Classification and evolution  

Energy Technology Data Exchange (ETDEWEB)

A study of the joint evolution of the normal- and neutron-star components of massive binaries opens with a classification scheme and the analytic expressions to be applied in Paper II for computer simulation of the observable properties of such systems.

1983-03-01

443

Myosin II transport, organization, and phosphorylation: evidence for cortical flow/solation-contraction coupling during cytokinesis and cell locomotion.  

UK PubMed Central (United Kingdom)

The mechanism of cytokinesis has been difficult to define because of the short duration and the temporal-spatial dynamics involved in the formation, activation, force production, and disappearance of...Full Text Available

1996-08-01

444

Multivesicular bodies in the enigmatic amoeboflagellate Breviata anathema and the evolution of ESCRT 0  

UK PubMed Central (United Kingdom)

Endosomal sorting complexes required for transport (ESCRTs) are heteromeric protein complexes required for multivesicular body (MVB) morphogenesis. ESCRTs I, II, III and III-associated are ubiquitous...Full Text Available

2011-02-15

445

Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance  

UK PubMed Central (United Kingdom)

Obesity and metabolic syndrome result from excess calorie intake and genetic predisposition and are mechanistically linked to type II diabetes and accelerated body aging; abnormal nutrient and insulin...Full Text Available

2010-07-27

446

MELCOR analyses of NUPEC`s large-scale hydrogen mixing test-II  

Energy Technology Data Exchange (ETDEWEB)

NUPEC has carried out hydrogen mixing tests to investigate hydrogen distribution behavior within a model containment and to provide a set of experimental data for validation of severe accident analysis codes.

1995-12-31

447

MAPPING THE INITIATOR BINDING TAF2 SUBUNIT IN THE STRUCTURE OF HYDRATED YEAST TFIID  

UK PubMed Central (United Kingdom)

SummaryThe general transcription factor TFIID is a large multi-subunit complex required for the transcription of most protein-encoding genes by RNA polymerase II. Taking advantage...Full Text Available

2009-03-11

448

Localization of a critical restriction site on the I-A beta chain that determines susceptibility to collagen-induced arthritis in mice.  

UK PubMed Central (United Kingdom)

Type II collagen-induced arthritis (CIA) in mice is an autoimmune experimental model for rheumatoid arthritis. Susceptibility to CIA is associated with certain major histocompatibility complex class...Full Text Available

1989-12-01

449

Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor  

UK PubMed Central (United Kingdom)

Mammals possess multiple insulin-like growth factor (IGF) binding proteins (IGFBPs), and related proteins, that modulate the activity of insulin/IGF signalling (IIS), a conserved neuroendocrine signalling...Full Text Available

2011-02-01

450

Leptin Resistance Protects Mice from Hyperoxia-induced Acute Lung Injury  

UK PubMed Central (United Kingdom)

Rationale: Human data suggest that the incidence of acute lung injury is reduced in patients with type II diabetes mellitus. However, the mechanisms by which diabetes confers protection...Full Text Available

2007-03-15

451

Interpreting the visible absorption bands of 1,4-(dihydroxy)-9,10-anthraquinone and its metal chelates.  

Science.gov (United States)

The visible absorption spectra of 1,4-(dihydroxy)-9,10-anthraquinone and of Co(II), Ni(II), Cu(II) and Zn(II) chelates have been studied in different organic solvents. This system provides a model for the anthracycline antibiotics and their metal chelates. The band structure of the spectrum has been determined using the second and fourth derivatives of the spectrum. The visible absorption band of the parent molecule can be assigned to a single electronic state with a reduced dipole moment in the excited state; structure in this band is ascribed to two overlapping vibrational progressions. In contrast, the dianion (hydroxy protons removed) shows a single electronic state with an increased dipole moment in the excited state; structure in this band can be assigned to a single vibrational progression. All of the metal chelates show spectra which are similar in appearance to that of the dianion although the ...

1990-08-15

452

Interleukin-7 mediates glucose utilization in lymphocytes through transcriptional regulation of the hexokinase II gene  

UK PubMed Central (United Kingdom)

The cytokine interleukin-7 (IL-7) has essential growth activities that maintain the homeostatic balance of the immune system. Little is known of the mechanism by which IL-7 signaling regulates metabolic...Full Text Available

2010-06-01

453

Institute of Plasma Physics, Academy of Sciences of the Czech Republic  

International Nuclear Information System (INIS)

The major activities of the various Institute's departments are highlighted. The following departments are included: (i) Tokamak; (ii) Pulse plasma systems; (iii) Thermal plasma; (iv) Materials engineering; (v) Laser plasma; and (vi) Optical diagnosis. (P.A.)

454

Immunomodulation by food: promising concept for mitigating allergic disease?  

UK PubMed Central (United Kingdom)

The importance of a properly functioning and well-balanced immune system for maintaining health has become strikingly evident over the past decades. Roughly since World War II, there has been an apparent...Full Text Available

2009-09-01

455

IgE antibodies to D. pteronyssinus in atopic patients.  

UK PubMed Central (United Kingdom)

An aqueous house dust mite extract was separated by SDS-PAGE and transferred to nitrocellulose membranes by Western Blotting. Two major allergens, Der pI and Der pII associated with the mite faeces...Full Text Available

1988-06-01

456

I. Cyclopeptide Alkaloids; II. Phycocyanobilipeptides.  

Science.gov (United States)

Several examples of the 14-membered, para-bridged ring system of the cyclopeptide alkaloids have been synthesized via an active ester cyclization. The yield of monomeric cyclopeptide varied from 1 to 33% and was affected by the amino acid substitution pat...

1979-01-01

457

High Efficiency Solar Cell on Low Cost Metal Foil Substrate  

Science.gov (United States)

During Phase II multi-junction solar cell will be grown on the large grain thin film produced during Phase I on flexible/low cost metal foil substrate. ...

458

Gas purification and decomposition plants  

Energy Technology Data Exchange (ETDEWEB)

The various steps of gas treatment in the Sasol II coal liquefaction plant are discussed: CO/sub 2/ removal, separation of the hydrocarbon fractions and the recirculated hydrogen by low-temperature decomposition, production of pure hydrogen by alternating pressure absorption.

1982-11-01

459

Federal Logistics Information System (FLIS) Procedures ...  

Science.gov (United States)

... II Item Identification 1,2,3,4,5,,3JAN Joint Army-Navy 2 5,6,13 IIM Item Intelligence 2 JANAP Joint Army-Navy-Air 2,7 Maintenance Force Publication ...

1995-01-01

460

Feature Selection and Classification of MAQC-II Breast Cancer and Multiple Myeloma Microarray Gene Expression Data  

UK PubMed Central (United Kingdom)

Microarray data has a high dimension of variables but available datasets usually have only a small number of samples, thereby making the study of such datasets interesting and challenging. In the task...Full Text Available

461

FLIS Procedures Manual. Multiple Application Procedures.  

Science.gov (United States)

... Volume(s) Volume(s) II Item Identification 1,2,3,4, JANAP Joint Army-Navy- 2,7 5,6,13 Air Force JIM Item Intelligence 2 Publication Maintenance ...

1996-10-01

462

Extended Gas in Seyfert Galaxies Near Infrared Observations of NGC 2110 and Circinus  

CERN Document Server

We present results of near--IR long-slit spectroscopy in the J and K bands of the Seyfert 2 galaxies NGC 2110 and Circinus, investigating the gaseous distribution, excitation, reddening and kinematics. In NGC 2110, the emission line ratio [FeII]/Pa beta increases towards the nucleus (to ~ 7). The nuclear [Fe II]1.257 (microns) and Pa beta lines are broader (FWHM ~ 500 km/s) than the H2 (2.121) line (FWHM ~ 300 km/s). Both these results suggest that shocks, driven by the radio jet, are an important source of excitation of [Fe II]. The H2 excitation appears to be dominated by X-rays from the nucleus. In Circinus, both [FeII]/Pa beta and H2/Br gamma decrease from ~ 2 at 4 arcsec from the nucleus to nuclear values of ~ 0.6 and ~ 1, respectively, suggesting that the starburst dominates the nuclear excitation, while the AGN dominates the excitation further out (r > 2 arcsec). For both galaxies, the gaseous ...

1998-01-01

463

Equilibrium, thermodynamic and kinetic studies for the biosorption of aqueous lead(II) ions onto the seed husk of Calophyllum inophyllum  

British Library Electronic Table of Contents (United Kingdom)

Biosorption of lead(II) ions from aqueous solution onto the seed husk of Calophyllum inophyllum was investigated in a batch system. Equilibrium, thermodynamics and kinetic studies were conducted by considering the effects of pH, initial metal ion concentration, contact time, and temperature. The results showed that the uptake of the metal ions increased with increase in initial metal ion concentration. The pH for optimum adsorption was 4 for the Pb(II) ions (q=4.86mg/g and 97.2% adsorption). Langmuir isotherm described the biosorption of Pb(II) ions onto the biomass (R^2=0.9531) better than the Freundlich model (R^2=0.7984), and the Temkin model (R^2=0.8761). Biosorption kinetics data obtained for the metal ions sorption were fitted using pseudo-first-order and pseudo-second-order. It was ...

2010-01-01

464

Equilibrium and kinetic studies for the biosorption system of copper(II) ion from aqueous solution using Tectona grandis L.f. leaves powder  

Energy Technology Data Exchange (ETDEWEB)

The biosorption of copper(II) ions from aqueous solution by Tectona grandis L.f. was studied in a batch adsorption system as a function of pH, metal ion concentration, adsorbent concentration and adsorbent size. The biosorption capacities and rates of copper(II) ions onto T. grandis L.f. were evaluated. The Langmuir, Freundlich, Redlich-Peterson and Temkin adsorption models were applied to describe the isotherms and isotherm constants. Biosorption isothermal data could be well interpreted by the Langmuir model with maximum adsorption capacity of 15.43 mg/g of copper(II) ion on T. grandis L.f. leaves powder. The kinetic experimental data properly correlated with the second-order kinetic model. Various thermodynamic parameters such as {delta}G{sup o}, {delta}H{sup o}, and {delta}S{sup o} were calculated indicating that this system was a spontaneous and exothermic process.

2006-09-21

465

Endometrial biopsy in Holstein-Friesian dairy cows. II. Correlations between histological criteria.  

UK PubMed Central (United Kingdom)

Endometrial biopsies were taken for histological assessment from 97 cows which calved in a commercial dairy herd between April and August 1984. The main objectives of this study were to analyze the...Full Text Available

1991-04-01

466

Electrochemical behavior of zirconium in the LiCl-KCl molten salt at Mo electrode  

British Library Electronic Table of Contents (United Kingdom)

The electroreduction process of Zr(IV) was studied at molybdenum electrode in LiCl-KCl-K2ZrF6 molten salt. The transient electrochemical techniques, such as cyclic voltammetry and chronopotenimetry were used. The experimental results showed that the electrochemical reduction of Zr(II)/Zr and Zr(IV)/Zr(II) were both diffusion-controlled process. In the 773-973K range, the diffusion coefficients of Zr(ii) and Zr(IV) were determined: DZr(II)=0.15567exp{-69.65x10^3RT(K)}cm^2/s, DZr(IV)=1.09x10^-^4exp{-44.39x10^3RT(K)}cm^2/s. The activation energy values for the diffusion process were 69.65kJ/mol and 44.39kJ/mol, respectively.

2011-01-01

467

Dynamics of ligand substitution in labile cobalt complexes resolved by ultrafast T-jump  

UK PubMed Central (United Kingdom)

Ligand exchange of hydrated metal complexes is common in chemical and biological systems. Using the ultrafast T-jump, we examined this process, specifically the transformation of aqua cobalt (II) complexes...Full Text Available

2008-09-02

468

Driving with Hemianopia, II: Lane Position and Steering in a Driving Simulator  

UK PubMed Central (United Kingdom)

Purpose.The hypothesis that drivers with homonymous hemianopia (HH) would take a lane position that increased the safety margin on their blind side was tested with a driving simulator.Methods.Twelve...Full Text Available

2010-12-01

469

Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice  

UK PubMed Central (United Kingdom)

Uncoupling protein 2 (UCP2) maps to a region on distal mouse chromosome 7 that has been linked to the phenotypes of obesity and type II diabetes. We recently reported that UCP2 expression is increased...Full Text Available

1998-03-31

470

Dexamethasone and nitric oxide synthase gene expression in brain.  

UK PubMed Central (United Kingdom)

Systemic administration of lipopolysaccharide (LPS), which causes endotoxemia and systemic inflammation, has been reported to induce expression of the gene for type II inducible nitric oxide synthase...Full Text Available

1997-03-01

471

Development on the technology for tritium removal processes (II).  

Science.gov (United States)

In order to decrease tritium exposure to workers, the ratio of which is up to 40% of total exposure, tritium removal facility is getting to be one of the considerable parameters in Korea, due to the next CANDUs to be operated at Wolsung NPP. For investiga...

1993-01-01

472

Dental caries: A complete changeover (Part II)-Changeover in the diagnosis and prognosis  

UK PubMed Central (United Kingdom)

Realization that dental caries is a reversible, dynamic biochemical event at a micron level has changed the way the profession recognizes the caries disease and the caries lesion. The diagnosis of dental...Full Text Available

2009-07-01

473

DISPERSION TOLERANCE CALCULATION FOR NSLS-II.  

Energy Technology Data Exchange (ETDEWEB)

In this paper we discuss the effect on the emittance of the residual dispersion in the insertion devices. The dispersion in the straights could be generated by the lattice error, trim dipole, and insertion device. The effect on the emittance is examined, and the dispersion tolerances are given for the NSLS-11.

2007-06-25

474

Crystalline O,O'-di-sec-butyl and O,O'-diethyl dithiophosphate platinum(II) complexes: Synthesis, 13C and 31P CP/MAS NMR, single crystal X-ray diffraction studies and thermal behaviour  

British Library Electronic Table of Contents (United Kingdom)

Crystalline bis(O,O'-di-sec-butyldithiophosphato)platinum(II) was prepared and studied by means of 13C, 31P CP/MAS NMR spectroscopy and single-crystal X-ray diffraction. The unit cell of the platinum(II) compound is comprised of one centrosymmetric mononuclear molecule [Pt{S2P(O-sec-C4H9)2}2], in which the dithiophosphate groups display structural equivalence in both 31P NMR and XRD data. A pair of the dithiophosphate ligands exhibit the same S,S'-bidentate chelating structural function and form two planar four-membered chelate rings, [PtS2P], in this molecule. The planar configuration of the [PtS4] chromophore in structure 1 is governed by the dsp2-hybrid state of platinum(II). The structural states of the dithiophosphate groups in two different samples of complex 1 (one crystallised from...

2011-01-01

475

Chiropteran types I and II interferon genes inferred from genome sequencing traces by a statistical gene-family assembler  

UK PubMed Central (United Kingdom)

BackgroundThe rate of emergence of human pathogens is steadily increasing; most of these novel agents originate in wildlife. Bats, remarkably, are the natural reservoirs of many...Full Text Available

476

Characterization of Photosystem II Activity and Heterogeneity during the Cell Cycle of the Green Alga Scenedesmus quadricauda1  

UK PubMed Central (United Kingdom)

The photosynthetic activity of the green alga Scenedesmus quadricauda was investigated during synchronous growth in light/dark cycles. The rate of O2 evolution increased...Full Text Available

1999-06-01

477

Chalk Point Cooling Tower Project: Chalk Point Meteorological Station Report. Volume II.  

Science.gov (United States)

This report documents the operation, maintenance, calibration, data acquisition and data reduction at the Chalk Point Meteorological Station for the period November 15, 1978 through November 15, 1979. Climatological data summaries for each month and calib...

1979-01-01

478

Cement-based composites: Strain rate effects on fracture  

Energy Technology Data Exchange (ETDEWEB)

This book contains over 20 selections. Some of the titles are: Continuum damage mechanics studies on the dynamic fracture of concrete; Dynamic compressive strength of cementitious materials; Rate-sensitivity of mode I and mode II fracture concrete; and An impact damage model of concrete.

1986-01-01

479

Calcium/Calmodulin-Dependent Protein Kinase II Mediates Hippocampal Glutamatergic Plasticity During Benzodiazepine Withdrawal  

UK PubMed Central (United Kingdom)

Benzodiazepine withdrawal anxiety is associated with potentiation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPAR) currents in hippocampal CA1 pyramidal...Full Text Available

2010-08-01

480

Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL  

UK PubMed Central (United Kingdom)

BackgroundThere is no consensus as to the prognostic model for brachytherapy of tongue carcinoma. This study was designed to evaluate the prognostic factors for local control based...Full Text Available

481

Bosjesspruit Colliery. [South Africa  

Energy Technology Data Exchange (ETDEWEB)

The reserves and the mine are described. Planned capacity is 27.5 million tonnes per year of coal for the Sasol II and Sasol III liquefaction plants. There will be 7 longwall faces, 15 entry workings with shotfiring, and 19 entries with continuous miners.

1982-02-18

482

Biosorption of heavy metals from wastewater by biosolids  

Energy Technology Data Exchange (ETDEWEB)

In a study where the removal of heavy metals from wastewater is the primary aim, the biosorption of heavy metals onto biosolids prepared as Pseudomonas aeruginosa immobilized onto granular activated carbon was investigated in batch and column systems. In the batch system, adsorption equilibriums of heavy metals were reached between 20 and 50 min, and the optimal dosage of biosolids was 0.3 g/L. The biosorption efficiencies were 84, 80, 79, 59 and 42 % for Cr(VI), Ni(II), Cu(II), Zn(II) and Cd(II) ions, respectively. The rate constants of biosorption and pore diffusion of heavy metals were 0.013-0.089 min{sup -1} and 0.026-0.690 min{sup -0.5}. In the column systems, the biosorption efficiencies for all heavy metals increased up to 81-100 %. The affinity of biosorption for various metal ions towards biosolids was decreased in the order: Cr = Ni > Cu > Zn > Cd. (Abstract Copyright ...

2006-08-15

483

Biosorption of Ni (II) by Schizosaccharomyces pombe: kinetic and thermodynamic studies  

British Library Electronic Table of Contents (United Kingdom)

The potential of the dried yeast, wild-type Schizosaccharomyces pombe, to remove Ni(II) ion was investigated in batch mode under varying experimental conditions including pH, temperature, initial metal ion concentration and biosorbent dose. Optimum pH for biosorption was determined as 5.0. The highest equilibrium uptake of Ni(II) on S. pombe, q e, was obtained at 25??C as 33.8?mg?g?1. It decreased with increasing temperature within a range of 25?50??C denoting an exothermic behaviour. Increasing initial Ni(II) concentration up to 400?mg?L?1 also elevated equilibrium uptake. No more adsorption took place beyond 400?mg?L?1. Equilibrium data fitted better to Langmuir model rather than Freundlich model. Sips, Redlich?Peterson, and Kahn isotherm equations modelled the investigated system with a...

2011-01-01

484

Beverage patterns and trends among school-aged children in the US, 1989-2008  

UK PubMed Central (United Kingdom)

BackgroundHigh intake of sugar-sweetened beverages in childhood is linked to increased risk of obesity and type II diabetes later in life. Using three nationally representative surveys...Full Text Available

485

Basement membrane chondroitin sulfate proteoglycan alterations in a rat model of polycystic kidney disease.  

UK PubMed Central (United Kingdom)

Alterations in basement membrane components, notably proteoglycans, in a rat model of polycystic kidney disease have been investigated. Rats were fed phenol II (2-amino-4-hydroxyphenyl-5-phenyl thiazole)...Full Text Available

1994-03-01

486

Assessment and Refinement of Real-Time Travel Time Algorithms for Use in Practice, Phase II.  

Science.gov (United States)

The Federal Highway Administration (FHWA) has put a high priority on the use of existing dynamic message signs (DMS) to provide travel time estimates to the public. The Oregon Department of Transportation (ODOT) has three DMS in the Portland metropolitan ...

2011-01-01

487

Apollo II - Thermal use of chicken droppings - Phase II; Apollo II - Thermische Nutzung von Huehnermist, Phase II  

Energy Technology Data Exchange (ETDEWEB)

This report made for the Swiss Federal Office of Energy (SFOE) discusses the conception, planning and construction of an easy-to-operate pilot heating plant that uses chicken litter as its fuel. The plant, which is installed at a chicken farm in Boesingen, Switzerland, produces 250 - 350 kW and not only supplies heat for two chicken sheds and two households, but also provides energy for a drying plant in summer. The results of measurements made on emissions are discussed and, within the framework of an eco-balance analysis, comparisons are made between the direct use of the droppings as manure or as a fuel. The cost-effectiveness of the plant is examined and the influence of plant size and other factors discussed. Further, legal questions concerning the use of chicken litter as a fuel for heating installations are discussed; the use of the droppings as a fuel is not foreseen in the legislation concerning water protection and airborne emissions of pollutants. Although normally this type ...

2001-07-01

488

Antisense Expression of the CK2 ?-Subunit Gene in Arabidopsis. Effects on Light-Regulated Gene Expression and Plant Growth1  

UK PubMed Central (United Kingdom)

The protein kinase CK2 (formerly casein kinase II) is thought to be involved in light-regulated gene expression in plants because...Full Text Available

1999-03-01

489

Angiotensin II Promotes Development of the Renal Microcirculation through AT1 Receptors  

UK PubMed Central (United Kingdom)

Pharmacologic or genetic deletion of components of the renin-angiotensin system leads to postnatal kidney injury, but the roles of these components in kidney development are unknown. To test the hypothesis...Full Text Available

2010-03-01

490

Analysis of Energy Consumption for Ad Hoc Wireless Sensor ...  

Science.gov (United States)

Aug 15, 2002 ... In Section II, we describe the routing and transceiver power model used ... In our power model, we assume a certain non-zero minimum level of ...

491

A second generation human haplotype map of over 3.1 million SNPs  

UK PubMed Central (United Kingdom)

We describe the Phase II HapMap, which characterizes over 3.1 million human single nucleotide polymorphisms (SNPs) genotyped in 270 individuals from four geographically diverse populations and...Full Text Available

2007-10-18

492

A faster pedigree-based generalized multifactor dimensionality reduction method for detecting gene-gene interactions  

UK PubMed Central (United Kingdom)

We proposed a faster pedigree-based generalized multifactor dimensionality reduction algorithm, called PedG-MDR II (PII), to detect gene-gene interactions underlying complex traits. Inherited...Full Text Available

2011-01-01

493

40 CFR 52.1426 - Original identification of plan section.  

Science.gov (United States)

...Department of Environmental Control to ASARCO Incorporated. (B) Amended Administrative...Department of Environmental Control to ASARCO Incorporated. (C) Second Amended...Department of Environmental Control to ASARCO Incorporated. (ii) Additional...

2010-07-01

494

33 CFR 148.105 - What must I include in my application?  

Science.gov (United States)

...capacity, and ownership of all planned and existing onshore pipelines, storage facilities, refineries, petrochemical...will be served by the port, including: (i) Onshore pipelines; (ii) Storage facilities; (iii)...

2010-07-01

495

29 CFR 1926.800 - Underground construction.  

Science.gov (United States)

...competent person shall inspect haulage equipment before each shift. (ii...used. (2) Powered mobile haulage equipment shall have suitable means of... (3)(i) Power mobile haulage equipment, including trains, shall...

2010-07-01

496

Underground Test Area Subproject Phase I Data Analysis Task. Volume II - Potentiometric Data Document Package  

Energy Technology Data Exchange (ETDEWEB)

Volume II of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the potentiometric data. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.

1996-12-01

497

Uncertainty analysis in fusion activation calculations: Application to the waste disposal assessment of HYLIFE-II structure  

International Nuclear Information System (INIS)

A computational procedure is proposed to perform uncertainty analysis for the calculation of the isotopic inventory and radiological quantities obtained as a linear function of it, due to uncertainties in the activation cross sections. The method is applied to determine the uncertainty of the calculated shallow burial index (SBI) from activated type 304 stainless steel (SS) in the most neutron-exposed zone of the HYLIFE-II vessel structure. Results are obtained by means of an element-by-element study. Some other types of steel are also investigated for comparison purposes. The SS304 is confirmed to be the most promising steel option. 16 refs., 2 tabs.

1996-06-16

498

Noncircular gas velocities and the radial dependence of mass-to-light ratio in NGC 4594 (the Sombrero Galaxy)  

International Nuclear Information System (INIS)

The mass distribution of the Sombrero Galaxy, NGC 4594, is calculated in order to investigate the suspicion that the rotational velocity of the galactic gas does not measure the circular velocity in the galaxy. It is shown that the H II rotation velocities are much less than circular in the central 35 arcsec of the galaxy, and that the suspicion is correct. Thus, the H II rotation velocities cannot be used to measure the mass distribution. The absorption-line rotation curve is used to derive the mass distribution, and it is found that the M/L ratio is nearly constant. It is concluded that the visible matter is self-gravitating at least in the central 180 arcsec. 44 references.

499

Correction of skeletal Class II-anterior deep bite and prominent chin by forced surgical rotation of the mandible  

British Library Electronic Table of Contents (United Kingdom)

The purpose of this paper is to describe a technique of forced surgical rotation of the mandible used in skeletal Class II patients with deep bite and prominent chin. Posterior occlusal composite onlays combined with preoperative orthodontic treatment without anterior intrusion increase the posterior rotational component of the surgical mandibular advancement, when removed during operation. This manoeuvre allows for the surgical closure of the posterior open bite, while anteriorly the deep bite is opened. This technique avoids bimaxillary rotation surgery with dorsal impaction in mild to moderate cases. In any case, a chin setback osteotomy with compromised aesthetics can be avoided.

2010-01-01