UK PubMed Central (United Kingdom)

SYNOPSISRhomboid proteases are a fascinating class of enzymes that combine a serine protease active site within the core of an integral membrane protein. Despite having key roles...Full Text Available

UK PubMed Central (United Kingdom)

Alterations in basement membrane components, notably proteoglycans, in a rat model of polycystic kidney disease have been investigated. Rats were fed phenol II (2-amino-4-hydroxyphenyl-5-phenyl thiazole)...Full Text Available

International Nuclear Information System (INIS)

A biodegradable polylactic acid (PLA)/poly(glycolide-co-lactide) copolymer (PLGA) membrane with polyglycolic acid (PGA) mesh was prepared to aid the effective regeneration of defective periodontal tissues. The microporous membrane used in this study consists of biodegradable polymers, and seems to have a structure to provide appropriate properties for periodontal tissue regeneration. Based on the albumin permeation test, it is known that the biodegradable membrane exhibits the suitable permeability of nutrients. The membrane maintained its physical integrity for 6-8 weeks, which could be sufficient to retain space in the periodontal pocket. Cell attachment and cytotoxicity tests were performed with respect to the evaluation of biocompatibility of the membrane. As a result, the membrane did not show any cytotoxicity. The safety and ...

British Library Electronic Table of Contents (United Kingdom)

To investigate the variation in the fine structure of polyamide thin-film composite (TFC) membranes prepared via two different interfacial polymerization conditions (IP-I and IP-II), experiments on Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM), water contact angle, and positron annihilation spectroscopy (PAS) coupled to a slow positron beam were conducted. Polyamide TFC membranes were prepared via the interfacial polymerization reaction between triethylenetetramine (TETA) and trimesoyl chloride (TMC) on the surface of a modified polyacrylonitrile (mPAN) membrane. Compared with the polyamide TFC membrane prepared via IP-I, the polyamide layer prepared via IP-II showed a shorter S plateau length (thinner thickness), a higher o-Ps intensity I3 value (higher free-volume con...

Science.gov (United States)

Although the mechanism is unknown, Calculus Bovis and its active components, cholic acid analogs (CAAs), have been used in China to treat a wide range of diseases. Based on the previous finding that the potency of CAA is strongly dependent on the intrinsic surface activity, this paper aimed to investigate the role of the plasma membrane in the pharmacological activity of CAAs. First, CAAs (0.1 mM) caused a surface activity-dependent depression on ATPase activity in the cell membrane extract, but it had no effects on other cellular extracts, suggesting an indispensable role of the membrane environment for pharmacological activity. Second, CAAs lowered the membrane fluidity of cultured Caco-2 cells with the same rank-order of potency sequence. Third, the hypothesis that any functional protein located on the membrane is influenced by changes in cellular membrane ...

UK PubMed Central (United Kingdom)

We identify new organelles associated with the vacuolar system in plant cells. These organelles are defined biochemically by their internal content of three integral membrane proteins: a chimeric reporter...Full Text Available

International Nuclear Information System (INIS)

An electrochemistry model was developed to analyse the J-V characteristics of a Proton Exchange Membrane (PEM) water electrolyzer for hydrogen production. The Butler-Volmer equation and water transport characteristics through electrolyte membrane were employed to simulate the electrode activation over-potential and membrane ohmic over-potential, respectively. The modeling results are found to agree reasonably well with experimental data published in the literature. The parametric simulations show that the ohmic over-potential is relatively small with typical water content in the membrane. Compared with the cathode over-potential, the anode over-potential is more significant and constitutes the major source of voltage loss. The high anode over-potential is due to the relatively slow oxidation kinetics, which is related to anode material property and microstructure. This model can be ...

Energy Technology Data Exchange (ETDEWEB)

A balanced application of chemiosmosis to plant mitochondria is presented. Electron transport carriers are sequenced to achieve proton translocation across the inner membrane. The processes of proton translocation, use, and release are integrated to yield a description of the effective proton gradient available for metabolite transport and ATP synthesis. 27 references, 6 figures.

UK PubMed Central (United Kingdom)

The acetylcholine receptor from the electric tissue of Torpedo californica is a large, integral membrane protein containing four different types of polypeptide chains. The structure of the purified...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This project is concerned with the structure and function of the unique antenna system found in the green photosynthetic bacteria. The antenna system in these organisms is contained within a vesicle known as a chlorosome, which is attached to the cytoplasmic side of the cell membrane. Additional antenna pigments and reaction centers are contained in integral membrane proteins. Energy absorbed by the bacteriochlorophyll c (BChl c) pigments in the chlorosome is transferred via a ``baseplate`` array of BChl a antenna pigments into the membrane and to the reaction center. This system is similar in some respects to the phycobilisome antenna system found in cyanobacteria and some types of algae, in that a membrane-associated structure absorbs light and transfers it to the membrane where conversion to chemical energy takes place. However, the overall structure, the ...

British Library Electronic Table of Contents (United Kingdom)

In this study, adipose-derived stem cells (ASCs) were cocultured with nucleus pulposus (NP) cells using a porous membrane to investigate the effect of NP cell phenotype on ASC chondrogenic differentiation. Human NP cells were collected from 14 patients and classified into two groups (normal vs. degenerative) depending on the level of type II collagen, aggrecan (AGG), type I collagen, and bax gene expression. Human ASCs were then cocultured with each group of NP cells on porous membranes in the absence of chondrogenic supplements. After 2 weeks, real-time-polymerase chain reaction results showed that ASCs cocultured with normal NP cells had much higher type II collagen and AGG gene expression than ASCs cocultured with degenerative NP cells. The production of AGG was also observed only in th...

British Library Electronic Table of Contents (United Kingdom)

Abstract Gaseous microemboli (GME) remain a challenge for cardiopulmonary bypass (CPB) because there is a positive correlation between microemboli exposure during CPB and postoperative neurological injury. Thus, minimizing the number of GME delivered to pediatric patients undergoing CPB procedures would lead to better clinical outcomes. In this study, we used a simulated CPB model to evaluate the effectiveness of capturing GME and the degree of membrane pressure drop for a new membrane oxygenator, Capiox Baby FX05 (Terumo Corporation, Tokyo, Japan), which has an integrated arterial filter with open and closed purge line. We used identical components in this study as our clinical CPB circuit. Three emboli detection and classification quantifier transducers were placed at prepump, preoxygena...

UK PubMed Central (United Kingdom)

Phospholamban (PLB) is a 52-amino acid integral membrane protein that helps to regulate the flow of Ca²⁺ ions in cardiac muscle cells. Recent structural studies on the PLB pentamer...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A technique for delivering genes carried by recombinant retroviruses into specific cell types could have numerous applications in oncology, developmental biology, and gene therapy. As a first step toward this remote goal the authors designed a procedure allowing in vitro cell targeting by retroviruses. Biotinylated antibodies against the viral envelope protein on one side, and against specific cell membrane markers on the other side, were bridged by streptavidin and used to link the virus to the host. The method was successfully used to infect human cells with ecotropic murine retroviruses by means of major histocompatibility complex class I and class II antigens and appears easily adaptable to other cell, membrane markers. Moreover, the sequential protocol they design, although allowing infection of human cells, requires less stringent safety constraints than would handling of amphotropic virus stocks.

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Culturing human prostate PC-3 cells for 4, 24, or 72 h in the presence of 5,8,11,14-eicosatetraynoic acid (ETYA), an inhibitor of arachidonic acid metabolism and cholesterol biosynthesis, markedly altered the morphology and reduced the number of mitochondria in the treated cells. Using quantitative electron microscopic morphometry, we documented changes in the number, form, area, matrix density, and integrity of the cristae and limiting membranes of mitochondria in cells cultured with ETYA. The inhibition of cholesterol synthesis or the substitution of ETYA for polyunsaturated fatty acids in the inner membrane may participate in the disruption of the mitochondria, which resembles the morphologic sequelae of oxidative stress. If sufficiently extensive, these changes could contribute to the inhibition of cellular proliferation by ETYA.

International Nuclear Information System (INIS)

We consider the spin-k/2 XXZ model in the antiferromagnetic regime using the free-field realization of the quantum affine algebra U_q(sl_2) of level k. We give a free-field realization of the type-II q-vertex operator, which describes creation and annihilation of physical particles in the model. By taking a trace of the type-I and type-II q-vertex operators over the irreducible highest-weight representation of U_q(sl_2), we also derive an integral formula for form factors in this model. Investigating the structure of poles, we obtain a residue formula for form factors, which is a lattice analog of the higher-spin extension of Smirnov's formula in the massive integrable quantum field theory. This result as well as the quantum deformation of the Knizhnik-Zamolodchikov equation for form factors shows a deep connection in the mathematical structure of the integrable lattice models and ...

International Nuclear Information System (INIS)

The single specimen unloading compliance technique has become the preferred method for evaluating J-integrals. It involves data acquisition and analysis using a computer. This paper describes in detail the development of a simple experimental system and related software that can be used in a laboratory equipped with a microcomputer and with access to a minicomputer. The effects of loading rate, test temperature, specimen geometry and material composition can be readily evaluated using this system. The results on a pressure vessel steel and an #alpha#-#beta# titanium alloy are discussed in Part II. (author).

CERN Document Server

In 1996 Jespers and Wang classified finite semigroups whose integral semigroup ring has finitely many units. In a recent paper, Iwaki-Juriaans-Souza Filho continued this line of research by partially classifying the finite semigroups whose rational semigroup algebra %over a field of characteristic zero, contains a ${\\mathbb{Z}}$-order with hyperbolic unit group. In this paper we complete this classification by handling the case in which the semigroup is semi-simple.

Energy Technology Data Exchange (ETDEWEB)

One of the key features of ANL's Integral Fast Reactor (IFR) concept is a close-coupled fuel cycle. The proposed fuel cycle is similar to that demonstrated over the first five to six years of operation of EBR-II, when a fuel cycle facility adjacent to EBR-II was operated to reprocess and refabricate rapidly fuel discharged from the EBR-II. Locating the IFR and its fuel cycle facility on the same site makes the IFR a self-contained system. Because the reactor fuel and the uranium blanket are metals, pyrometallurgical processes (shortned to ''pyroprocesses'') have been chosen. The objectives of the IFR processes for the reactor fuel and blanket materials are to (1) recover fissionable materials in high yield; (2) remove fission products adequately from the reactor fuel, e.g., a decontamination factor of 10 to 100; and (3) upgrade the concentration of plutonium ...

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The plastic displacements around Knoop indentations made in hard titanium/aluminum multilayered films on soft aluminum alloy substrates have been studied. Indentations were cross-sectioned and imaged using the focused-ion-beam (FIB) milling and high-resolution scanning electron microscopy (SEM), respectively. The FIB milling method has the advantage of removing material in a localized region without producing mechanical damage to the specimen. The micrographs of the cross-sectioned indentations indicate that most of the plastic deformation around the indentation is dominated by the soft aluminum substrate. There is a very small change in the multilayered film thickness around the indentation{emdash}less than 10{percent}. The plastic deformation of the thin film resembles a membrane being deflected by a localized pressure gradient across the membrane. Stress-induced voids are also observed in the multilayered film, especially in the area around ...

Energy Technology Data Exchange (ETDEWEB)

The objective of this research project is to demonstrate sensing, communication, information and control technologies to achieve a seamless integration of multivendor distributed energy resource (DER) units at aggregation levels that meet individual user requirements for facility operations (residential, commercial, industrial, manufacturing, etc.) and further serve as resource options for electric and natural gas utilities. The fully demonstrated DER aggregation system with embodiment of communication and control technologies will lead to real-time, interactive, customer-managed service networks to achieve greater customer value. Work on this Advanced Communication and Control Project (ACCP) consists of a two-phase approach for an integrated demonstration of communication and control technologies to achieve a seamless integration of DER units to reach progressive levels of aggregated power output. Phase I involved design ...

Science.gov (United States)

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UK PubMed Central (United Kingdom)

Membrane protein structural biology is still a largely unconquered area, given that approximately 25% of all proteins are membrane proteins and yet less than 150 unique structures are available. Membrane...Full Text Available

KoreaScience (Korea)

Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The Integral Fast Reactor is an innovative liquid metal reactor concept that is being developed by Argonne National Laboratory. It takes advantage of the properties of metallic fuel and liquid metal cooling to offer significant improvements in reactor safety, operation, fuel cycle economics, environmental protection, and safeguards. The plans for demonstrating the IFR fuel cycle, including its waste processing options, by processing irradiated fuel from the Experimental Breeder Reactor-II fuel in its associated Fuel Cycle Facility have been developed for the first refining series. This series has been designed to provide the data needed for the further development of the IFR program. An important piece of the data needed is the recovery of TRU material during the reprocessing and waste operations.

Energy Technology Data Exchange (ETDEWEB)

The objectives of the project were (i) to develop a combination iron oxide production and carbon sequestration plant that will use serpentine ores as the source of iron and the extraction tailings as the storage element for CO2 disposal, (ii) the identification of locations within the US where this process may be implemented and (iii) to create a standardized process to characterize the serpentine deposits in terms of carbon disposal capacity and iron and steel production capacity. The first objective was not accomplished. The research failed to identify a technique to accelerate direct aqueous mineral carbonation, the limiting step in the integration of steel production and carbon sequestration. Objective (ii) was accomplished. It was found that the sequestration potential of the ultramafic resource surfaces in the US and Puerto Rico is approximately 4,647 Gt of CO2 or over 500 years of current US production of CO2. ...

Energy Technology Data Exchange (ETDEWEB)

This document contains the Proceedings of the Eleventh Thematic Conference Geologic Remote Sensing (Volume II). The conference was held February 27-29, 1996 in Las Vegas, Nevada, USA. Presentations included in this volume address the following topics: Geologic Remote Sensing and aerial surveying as applied toward mineral exploration, monitoring of geothermal resources, petroleum exploration, the environmental effects of mining, environment and hydrology, detection of geohazards, and the GIS system and data integration. Some information regarding the use of color imagery in remote sensing is also included.

British Library Electronic Table of Contents (United Kingdom)

a-Dystroglycan is an extracellular adhesion protein that is known to interact with different ligands. The interaction is thought to stabilize the integrity of the plasma membrane. The N-terminal part of a-dystroglycan may be proteolytically processed to generate a small 38kDa protein (a-DG-N). The physiological significance of a-DG-N is unclear but has been suggested to be involved in nerve regeneration and myelination and to function as a potential biomarker for neurodegenerative and neuromuscular diseases. In this report we show that a-DG-N is released into different body fluids, such as lachrimal fluid, cerebrospinal fluid (CSF), urine and plasma. To investigate the significance of a-DG-N in CSF we examined the levels of a-DG-N and known neurodegenerative markers in CSF from patients di...

DEFF Research Database (Denmark)

We study the spike statistics of neurons in a network with dynamically balanced excitation and inhibition. Our model, intended to represent a generic cortical column, comprises randomly connected excitatory and inhibitory leaky integrate-and-fire neurons, driven by excitatory input from an external population. The high connectivity permits a mean field description in which synaptic currents can be treated as gaussian noise, the mean and autocorrelation function of which are calculated self-consistently from the firing statistics of single model neurons. Within this description, a wide range of Fano factors is possible. We find that the irregularity of spike trains is controlled mainly by the strength of the synapses relative to the difference between the firing threshold and the postfiring reset level of the membrane potential. For moderately strong synapses, we find spike statistics very similar to those observed in primary visual cortex.

International Nuclear Information System (INIS)

The human erythrocyte (RBC) Rh blood group system consists of a complex of distinct integral membrane polypeptides with physical properties common to the aminophospholipid transporter responsible for the transbilayer movement of phosphatidylserine (PS) in RBC. To assess the involvement of Rh polypeptides in PS translocation, the aminophospholipid translocase was labeled with a photoactivatable PS analogue, "1"2"5I-azido-PS, and with an inhibitor of PS transport, "1"2"5I-labeled 2-(2-pyridyldithio)ethylamine. The ability of monoclonal Rh antibodies to immunoprecipitate the labeled transporter was determined. Immunoprecipitated Rh polypeptides were found to be labeled with the aminophospholipid translocase markers, suggesting that Rh proteins are involved in the transbilayer movement of PS.

British Library Electronic Table of Contents (United Kingdom)

The integral membrane protein synaptophysin is one of the most abundant polypeptide components of synaptic vesicles. It is not essential for neurotransmission despite its abundance but is believed to modulate the efficiency of the synaptic vesicle cycle. Detailed behavioral analyses were therefore performed on synaptophysin knockout mice to test whether synaptophysin affects higher brain functions. We find that these animals are more exploratory than their wild type counterparts examining novel objects more closely and intensely in an enriched open field arena. We also detect impairments in learning and memory, most notably reduced object novelty recognition and reduced spatial learning. These deficits are unlikely caused by impaired vision, since all electroretinographic parameters measur...

Energy Technology Data Exchange (ETDEWEB)

The hypothesis that accumulation against sizable chemical gradients of free (non-phosphorylated) 2-deoxy-D-glucose (2dGlc) in isolated rat adipocytes results from an intracellular compartmentation of free hexose was investigated. Cells exposed to 20 ..mu..g/ml digitonin for 10' demonstrated an increased plasma membrane permeability indexed by increased L-glucose entry rates and cellular (presumably cytosolic) protein and K/sup +/ loss. Functional integrity of intracellular organelles was indicated by the ability of the cells to support ATP-driven /sup 45/Ca/sup 2 +/-uptake. Equilibrium 3-O-methylglucose (3-O-MG, a non-accumulated hexose) levels were unaffected. These data suggest a specific permeabilizing action of digitonin at the plasma membrane having no effect on intracellular organelles or passively distributed solutes. Upon addition of digitonin, free 2dGlc fell from 66.5 +/- 8.9 to 7.4 +/- 2.3 pmol/10/sup 5/ ...

International Nuclear Information System (INIS)

Electricity generation from natural gas in gas turbine units can be made substantially more efficient by preliminary methane conversion to a synthesis gas containing hydrogen and carbon monoxide and/or by the use of some of the synthesis gas produced in industry. An alternative improvement involves the introduction of solid oxide fuel cells (SOFCs) and the use of the synthesis gas in them. In this study, a modified scheme of gas turbine cycle that includes an SOFC, a membrane reactor (instead of a traditional combustion chamber), and a catalytic reactor to perform methane conversion to produce hydrogen (synthesis gas) is proposed. Variations of the energy and exergy efficiencies of the integrated system with operating conditions are provided, showing, for example, that SOFC efficiency is enhanced if the fuel cell active area is augmented. The SOFC stack efficiency can be maximized by reducing the steam generation while increasing the stack ...

CERN Document Server

This paper is about algebro-geometrical structures on a moduli space $\\CM$ of anomaly-free BV QFTs with finite number of inequivalent observables or in a finite superselection sector. We show that $\\CM$ has the structure of F-manifold -- a linear pencil of torsion-free flat connection with unity on the tangent space, in quantum coordinates. We study the notion of quantum coordinates for the family of QFTs, which determines the connection 1-form as well as every quantum correlation function of the family in terms of the 1-point functions of the initial theory. We then define free energy for an unital BV QFT and show that it is another avatar of morphism of QFT algebra. These results are consequences of the solvability of refined quantum master equation of the theory. We also introduce the notion of a QFT integral and study some properties of BV QFT equipped with a QFT integral. We show that BV QFT with a non-degenerate QFT ...

Science.gov (United States)

A sulfonated fluoroalkyl graft polymer (FGP) membrane was prepared as a polymer electrolyte. First, the FGP membrane was grafted with styrene under UV irradiation. The grafted FGP was then sulfonated to functionalize it for proton conductivity. The grafting degree of the membrane increased with increasing grafting time during UV irradiation. The proton conductivity of the membrane increased with increasing grafting degree. The swelling ratio was independent of the grafting time, however, the water uptake increased with increasing grafting degree. Based on these results, it was found that the UV-initiated styrene grafting occurred along the membrane thickness direction. Moreover, the membrane was embedded within the glass fibers of the composite. This composite electrolytic membrane had 1.15 times the proton conductivity of a Nafion 117 ...

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Antitumor platinum(II) complexes derived from N-alkyl-propanediamine differing in the length of their carbon chain (C8, C10, C12 and C14) were incorporated in liposomes and the cytotoxic activity of these formulations was evaluated against tumor (A{sub 549}, MDA-MB-231, B16-F1 and B16-F10) and non-tumor (BHK-21 and CHO) cell lines. Stable and monodisperse liposome suspensions incorporating the platinum complexes were obtained from the lipid composition consisting of distearoyl-sn-glycero-3-phosphocholine, cholesterol and 1,2-distearoyl-sn-glycero- 3-phosphoethanolamine-N-(methoxy(polyethylene glycol)-2000) at 5:3:0.3 molar ratio. The entrapment efficiency (EE%) of the platinum complexes in liposomes increased with the carbon chain length. EE% was higher than 80% in C12- and C14-derivatives. The effect of liposome encapsulation on the cytotoxic activity of the complexes was found to depend on the carbon chain length. These data indicate that the highest drug ...

CERN Document Server

Integrating mission and strategy for nonprofit organizations

Science.gov (United States)

A computer program entitled "Marshall Aerospace Vehicle Representation in C II,

UK PubMed Central (United Kingdom)

In vitro the binding of polyribosomes to smooth endoplasmic-reticulum membranes is more sensitive to ionic strength than is the binding to rough endoplasmic-reticulum membranes. Polyribosomes...Full Text Available

UK PubMed Central (United Kingdom)

In the presence of electrochemical energy, several branched-chain neutral and acidic amino acids were found to accumulate in membrane vesicles of Bacillus stearothermophilus. The membrane vesicles contained...Full Text Available

UK PubMed Central (United Kingdom)

Spontaneous rupture of membranes (ROM) is a normal component of labor and delivery. Premature ROM (PROM) refers to rupture of the fetal membranes prior to the onset of labor irrespective of gestational...Full Text Available

UK PubMed Central (United Kingdom)

The biophysical properties of membrane phospholipids are controlled by the composition of their constituent fatty acids and are tightly regulated in Escherichia...Full Text Available

Science.gov (United States)

Proton exchange membrane (PEM) fuel cells are energy sources that have the ... for H2 /02 PEM fuel cells because their catalysts have properties suitable for 0 ...

British Library Electronic Table of Contents (United Kingdom)

The impacts of the availability of low-carbon technologies on the regional distribution of mitigation costs are analyzed in a global multi-regional integrated assessment model. Three effects on regional consumption losses are distinguished: domestic measures, trade of fossil energy carriers and trade of emission permits. Key results are: (i) GDP losses and a redirection of investments in the energy system towards capital-intensive technologies are major contributions to regional consumption losses. (ii) A devaluation of tradable fossil energy endowments contributes largely to the mitigation costs of fossil fuel exporters. (iii) In case of reduced availability of low-carbon technologies, the permit market volume and associated monetary redistributions increase. The results suggest that the ...

British Library Electronic Table of Contents (United Kingdom)

For the safety of astronauts and to ensure the stability and integrity of the genome of microorganisms and plants used in bioregenerative life support systems, it is important to improve our knowledge of the combined action of (space) radiation and microgravity. The SOS-LUX-TOXICITY test, as part of the TRIPLE-LUX project (accepted for flight at Biolab in Columbus on the International Space Station, (ISS)), will provide an estimation of the health risk resulting from exposure of astronauts to the radiation environment of space in microgravity. The project will: (i) increase our knowledge of biological/health threatening action of space radiation and enzymatic DNA repair; (ii) uncover cellular mechanisms of synergistic interaction of microgravity and space radiation; (iii) provide specified...

Energy Technology Data Exchange (ETDEWEB)

Severe accident analysis has been performed for the Wolsung nuclear power plants in Korea to investigate severe accident phenomena of CANDU-600 reactors as a part of Level II PSA study. The accident sequence analyzed in this paper is loss of active heat sinks (LOAH) which is caused by loss of off-site power, diesel generators, and DC power, ISAAC(Integrated Severe Accident Analysis Code) computer code developed by KAERI (Korea Atomic Energy Research Institute) was used in this analysis. This paper describes the important thermal-hydraulics and source term behaviors in the primary system and inside containment, and the failure mechanisms of calandria vessel and containment. In addition, some insights for accident management program (AMP) are also given.

International Nuclear Information System (INIS)

The point at which the common final pathway for induction of cancer by chemical carcinogens and ionizing radiation has not been identified. Although common molecular targets are suggested by recent findings about the role of oncogenes, the mechanism by which the deposition of radiation energy and the formation of adducts or other DNA lesions induced by chemicals affects the changes in the relevant targets may be quite different. The damage to DNA that plays no part in the transformation events, but that influences the stability of the genome, and therefore, the probability of subsequent changes that influence tumorigenesis may be more readily induced by some agents than others. Similarly, the degree of cytotoxic effects that disrupt tissue integrity and increase the probability of expression of initiated cells may be dependent on the type of carcinogen. Also, evidence was presented that repair of the initial lesions could be demonstrated after exposure to low-LET ...

Energy Technology Data Exchange (ETDEWEB)

Evidence is reported for a narrow structure near the J/{psi}{phi} threshold in exclusive B{sup +} {yields} J/{psi}{phi}K{sup +} decays produced in {bar p}p collisions at {radical}s = 1.96 TeV. A signal of 14 {+-} 5 events, with statistical significance in excess of 3.8 standard deviations, is observed in a data sample corresponding to an integrated luminosity of 2.7 fb{sup -1}, collected by the CDF II detector. The mass and natural width of the structure are measured to be 4143.0 {+-} 2.9(stat) {+-} 1.2(syst) MeV/c{sup 2} and 11.7{sub -5.0}{sup +8.3}(stat) {+-} 3.7(syst) MeV/c{sup 2}.

British Library Electronic Table of Contents (United Kingdom)

The concept of sustainable consumption (SC) has been proposed as a way of operationalising sustainable development (SD). However, until now, in view of the difficulties in conceptualising SC, emphasis has been placed mainly on a pragmatic approach. In an a-conceptual and pragmatic account of SC, many problems remain unaddressed, such as the danger of the notion becoming empty and lack of integration between the different dimensions of sustainability. In this paper, we propose that the informational space provided by the capability approach (CA) offers a conceptual framework to elaborate SC. The CA is employed here (i) to discuss the philosophical underpinnings of SC as part of a strategy for enhancing quality-of-life and (ii) to investigate the links between the different dimensions of SC....

Science.gov (United States)

Twenty autopsy cases with 2009 pandemic influenza A (2009 H1N1) virus infection, performed between August 2009 and February 2010, were histopathologically analyzed. Hematoxylin-eosin staining, immunohistochemistry for type A influenza nucleoprotein antigen, and real-time reverse transcription-PCR assay for viral RNA were performed on formalin-fixed and paraffin-embedded specimens. In addition, the D222G amino acid substitution in influenza virus hemagglutinin, which binds to specific cell receptors, was analyzed in formalin-fixed and paraffin-embedded trachea and lung sections by direct sequencing of PCR-amplified products. There were several histopathological patterns in the lung according to the most remarkable findings in each case: acute diffuse alveolar damage (DAD) with a hyaline membrane (four cases), organized DAD (one case), acute massive intra-alveolar edema with variable degrees of hemorrhage (three cases), neutrophilic bronchopneumonia (five cases) and ...

Energy Technology Data Exchange (ETDEWEB)

Because every cell within the body has the same genetic information, a significant problem in biology is to understand how cells within a tissue express genes selectively. A sophisticated network of physical and biochemical signals converge in a highly orchestrated manner to bring about the exquisite regulation that governs gene expression in diverse tissues. Thus, the ultimate decision of a cell to proliferate, express tissue-specific genes, or apoptose must be a coordinated response to its adhesive, growth factor, and hormonal milieu. The unifying hypothesis examined in this overview is that the unit of function in higher organisms is neither the genome nor the cell alone but the complex, three-dimensional tissue. This is because there are bidirectional connections between the components of the cellular microenvironment (growth factors, hormones, and extracellular matrix) and the nucl2048 These connections are made via membrane-bound receptors and transmitted to ...

Energy Technology Data Exchange (ETDEWEB)

On-board reforming of liquid fuels to hydrogen for use in proton exchange membrane (PEM) fuel cell electric vehicles (FCEVs) has been the subject of numerous investigations. In many respects, liquid fuels represent a more attractive method of carrying hydrogen than compressed hydrogen itself, promising greater vehicle range, shorter refilling times, increased safety, and perhaps most importantly, utilization of the current fuel distribution infrastructure. The drawbacks of on-board reformers include their inherent complexity [for example a POX reactor includes: a fuel vaporizer, a reformer, water-gas shift reactors, a preferential oxidation (PROX) unit for CO cleanup, heat exchangers for thermal integration, sensors and controls, etc.], weight, and expense relative to compressed H{sub 2}, as well as degraded fuel cell performance due to the presence of inert gases and impurities in the reformate. Partial oxidation (POX) of automotive fuels is ...

Energy Technology Data Exchange (ETDEWEB)

The conversion of off-peak surplus electricity into peak electricity through an electrolyzer, hydrogen storage, and fuel cell energy storage system was discussed. Development efforts in high pressure alkaline electrolysis and Proton-Exchange Membrane (PEM) fuel cells have improved the near-term viability of these systems. Potential use of wind turbines and other renewable energy-based generation systems, through hydrogen-based energy storage, were discussed as a new supply of surplus electricity. An integrated set of nomographs were presented for providing quick estimates of peak electricity costs derived from an electrolyzer/hydrogen fuel cell system. The nomographs allowed first order cost comparisons of centralized versus distributed hydrogen energy systems considering trade-offs between production economies of scale and hydrogen storage and transport costs. Use of the nomographs to compare centralized and dispersed systems was demonstrated. ...

International Nuclear Information System (INIS)

... v. 14(8) p. 624-625. azido compounds cadmium complexes potentiometry

International Nuclear Information System (INIS)

... females in vitro intestines lead 203 mucous membranes radionuclide kinetics

Science.gov (United States)

PMID:10831980

Energy Technology Data Exchange (ETDEWEB)

The conductivity of the membrane is a limiting factor for the efficiency and power density of PEFCs. Because this conductivity is strongly dependent on the membrane hydration, water management is an important aspect of PEFC optimisation. Single cell model experiments were made in order to determine the in-plane hydration of a Nafion{sup R} membrane under fuel cell conditions as function of the gas humidities. (author) 4 fig., 3 refs.

KoreaScience (Korea)

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Science.gov (United States)

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International Nuclear Information System (INIS)

Sulfonated poly(ether ether ketone) (SPEEK) membranes with various degrees of sulfonation (DS) have been prepared as a potential membrane material for proton exchange membrane by sulfonation process using mixtures of (15-30% concentration) fuming sulfuric acid and (95-98%) concentrated sulfuric acid as the sulfonating agent. The sulfonation process was conducted at room temperature by varying the acid ratio and reaction time. The produced membranes were then characterized by evaluating the ion exchange capacity (IEC), water uptake, thermal stability, proton conductivity and methanol permeability as a function of degree of sulfonation. The proton conductivity of the sulfonated PEEK membranes with various DS was within the magnitude of 10"-"3 and 10"-"2 S cm"-"1 at room temperature and the methanol permeability was in the range of 3.45 x 10"-"7 to 2.73 x 10"-"6 cm"2 s"-"1. The overall ...

International Nuclear Information System (INIS)

Equivalent circuit and electrical parameters for H-doped NH_4UO_2PO_4.3H_2O self supported membranes have been determined by impedance spectroscopy. The measurements were carried out with a dry membrane, at different temperatures, and a wet membrane in contact with different electrolyte solutions. Resistance values for the dry membrane decrease with temperature increase, which agrees with the weak protonic character of the H-doped ammonium uranylphosphate. On the other hand, differences in the electrical parameters, depending on the electrolyte considered were also obtained and are attributed to different conduction mechanisms. (Author).

Energy Technology Data Exchange (ETDEWEB)

The first analysis of inelastic J/{psi} meson production in photoproduction (Q{sup 2}<2.5 GeV{sup 2}) of the H1 experiment for the second phase of HERA (HERA II) is presented. The analysis is carried out at low and medium elasticities. The production of heavy quarks (charm, or bottom) is of special interest since the mass of the quarks provides a hard scale for the application of perturbative QCD. The muonic decay channel is used to select the J/{psi} mesons. The data was collected by the H1 detector during the period 2003-2005, and corresponds to an integrated luminosity of 133 pb{sup -1}. However only a subset of this data could be analysed. At the start of HERA II the trigger system was affected by a sizeable background. Then a fault was introduced in the trigger software during the summer 2004 and was only discovered and solved in April 2006. This means that approximately 80 % of the triggered events at medium ...

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

International Nuclear Information System (INIS)

Early effects of 100 Kilorads of X-rays on muscle cell membrane properties have been measured in sartorius muscles from Leptodactylus ocellatus. Threshold strength for rectangular current pulses increased 10% after irradiation, and action potential propagation velocity decreased 10%. Passive membrane parameters were calculated from potential responses to sub-threshold current pulses, assuming conventional cable theory. Specific membrane conductance increased to 18% after irradiation, membrane capacitance increased 14%, and length constant decreased 10% but membrane time constant was unchanged. Cell diameter decreased 5%, and resting membrane potential decreased 8%. Membrane parameters during an action potential were also evaluated by the phase-plane and current-voltage plot techniques. Irradiation significantly decreased the action potential ...

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Energy Technology Data Exchange (ETDEWEB)

In its current configuration, the IECM provides a capability to model various conventional and advanced processes for controlling air pollutant emissions from coalfired power plants before, during, or after combustion. The principal purpose of the model is to calculate the performance, emissions, and cost of power Plant configurations employing alternative environmental control methods. The model consists of various control technology modules, which may be integrated into a complete utility plant in any desired combination. in conuwt to conventional deterministic models, the IECM offers the unique capability to assign probabilistic values to all model input parameters, and to obtain probabilistic outputs in the form of cumulative distribution functions indicating the likelihood of different costs and performance results. The most recent version of the IECM, implemented on a Macintosh II computer and containing a number of software and model ...

British Library Electronic Table of Contents (United Kingdom)

Gas separation membranes with polydimethylsiloxane(PDMS)/polystyrene(PS) were prepared by using the sequential interpenetrating polymer network (IPN) method with various PS contents (10?70wt%). These gas separation membranes can be applied to reduce the smoke density in the emission gas of diesel engines. PS content has a pronounced effect on the membrane performance. It was found that the optimized PS contents in the final membrane were 50wt%. The emission capacities of diesel engines used in this study were 632 cc and 11,149 cc. When the oxygen separation membrane was used in the diesel engines, the smoke density of both diesel engines was remarkably reduced (35?73%). The oxygen concentration in the inlet air affects the composition of the emission gases. Especially, hydrocarbon (HC) dec...

Energy Technology Data Exchange (ETDEWEB)

Basic fibroblast growth factor (bFGF) exhibits specific binding to the extracellular matrix (ECM) produced by cultured endothelial cells. Binding was saturable as a function both of time and of concentration of {sup 125}I-bFGF. Scatchard analysis of FGF binding revealed the presence of about 1.5 x 10{sup 12} binding sites/mm{sup 2} ECM with an apparent k{sub D} of 610 nM. FGF binds to heparan sulfate (HS) in ECM as evidenced by (i) inhibition of binding in the presence of heparin or HS at 0.1-1 {mu}g/mL, but not by chondroitin sulfate, keratan sulfate, or hyaluronic acid at 10 {mu}g/mL, (ii) lack of binding to ECM pretreated with heparitinase, but not with chondroitinase ABC, and (iii) rapid release of up to 90% of ECM-bound FGF by exposure to heparin, HS, or heparitinase, but not to chondroitin sulfate, keratan sulfate, hyaluronic acid, or chondroitinase ABC. Oligosaccharides derived from depolymerized heparin, and as small as the tetrasaccharide, released the ...

UK PubMed Central (United Kingdom)

The canonical Wnt/β-catenin pathway plays a pivotal role in regulating embryogenesis and tumorigenesis by promoting cell proliferation. BAMBI (BMP and activin membrane-bound inhibitor) has...Full Text Available

UK PubMed Central (United Kingdom)

A number of studies have indicated that plasma membrane calcium ATPases (PMCAs) are expressed in the brain and spinal cord and could play important roles not only in the maintenance of cellular calcium...Full Text Available

UK PubMed Central (United Kingdom)

Tubular membrane structures are widespread in eukaryotic cells, but the mechanisms underlying their formation and stability are not well understood. Previous work has focused on tube extrusion from...Full Text Available

UK PubMed Central (United Kingdom)

The localization of gold in the synovial membrane of rheumatoid arthritis patients treated with sodium aurothiomalate was examined and quantitative analysis of epon-embedded sections was carried out...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Membranous dysmenorrhea is an unusual clinical entity. It is characterized by the expulsion of huge fragments of endometrium during the menses, favored by hormonal abnormality or drug intake. This report describes a case with clinical, US, and MRI findings before the expulsion. Differential diagnoses are discussed. (orig.)

CERN Document Server

Cell membranes are studded with protrusions that were thoroughly analyzed with electron microscopy. However, the nanometer-scale three-dimensional motions generated by cell membranes to fit the topography of foreign surfaces and initiate adhesion remain poorly understood. Here, we describe the dynamics of surface deformations displayed by monocytic cells bumping against fibronectin-coated surfaces. We observed membrane undulations with typically 5 nm amplitude and 5-10 second lifetime. Cell membranes behaved as independent units of micrometer size. Cells detected the presence of foreign surfaces at 50 nm separation, resulting in time-dependent amplification of membrane undulations. Molecular contact then ensued with apparent cell-membrane separation of 30-40 nm, and this distance steadily decreased during the following tens of seconds. Contact maturation was ...

UK PubMed Central (United Kingdom)

The binding of amphiphilic molecules to lipid bilayers is followed by ¹⁹F NMR using chemical shift and line shape differences between the solution and membrane-tethered states of...Full Text Available

UK PubMed Central (United Kingdom)

Objective: To evaluate effects of epigallocatechin-3-gallate (EGCG) on the viability, membrane properties, and zinc distribution, with and without the presence of Zn²⁺, in human prostate...Full Text Available

UK PubMed Central (United Kingdom)

Measurement of intrathylakoid aqueous volumes by electron spin resonance spectroscopy was used to study ionic permeability properties of thylakoid membranes isolated from Beta vulgaris...Full Text Available

UK PubMed Central (United Kingdom)

Electron spin resonance (ESR) studies have been performed on spin-labeled model membranes aligned using the isopotential spin-dry ultracentrifugation (ISDU) method of Clark and Rothschild. This method...Full Text Available

UK PubMed Central (United Kingdom)

Transitions at 28-32°C in membranes of many kinds of seeds influence their germination and subsequent growth. Changes at 28-32°C in the rates of loss of endogenous amino acids from imbibed...Full Text Available

UK PubMed Central (United Kingdom)

The molecular diversity of the gene encoding the outer membrane protein A (OmpA) of Haemophilus parasuis has been unclear. In this study, the structural characteristics, sequence types,...Full Text Available

UK PubMed Central (United Kingdom)

Biological membranes are lamellar structures composed of two leaflets capable of supporting different mechanical stresses. Stress differences between leaflets were generated during micromechanical experiments...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The authors present a search for excited and exotic muon states {mu}*, conducted using an integrated luminosity of 371 pb{sup -1} of data collected in p{bar p} collisions at {radical}s = 1.96 TeV at the Tevatron with the CDF II detector. They search for associated production of {mu}{mu}* followed by the decay {mu}* {yields} {mu}{gamma}, resulting in the {mu}{mu}{gamma} final state. They compare the data to model predictions as a function of the mass of the excited muon M{sub {mu}*}, the compositeness energy scale {Lambda}, and the gauge coupling factor f. No signal above the standard model expectation is observed in the {mu}{gamma} mass spectrum. In the contact interaction model, they exclude 107 < M{sub {mu}*} < 853 GeV/c{sup 2} for {Lambda} = M{sub {mu}*}; in the gauge-mediated model, they exclude 100 < M{sub {mu}*} < 410 GeV/c{sup 2} for f/{Lambda} = 10{sup -2} GeV{sup -1}. These 95% confidence level exclusions ...

Energy Technology Data Exchange (ETDEWEB)

A laboratory differential simulation method is used for the design of carbonization columns at coal-tar processing in which phenols are regenerated from phenolate solution by carbon dioxide absorption. The design method is based on integration of local absorption rates of carbon dioxide along the column. The local absorption rates into industrial phenolate mixture are measured in a laboratory model contactor for various compositions of the gas and liquid phases under the conditions that ensure the absorption rates in the laboratory absorber simulate the local rates in the industrial column. On the bases of the calculations, two-step carbonization columns were designed for 30000 t/year of the phenolate solution treatment by carbon dioxide. The absorption proceeds at higher pressure of 500 kPa and temperatures from 50 to 65 C, pure carbon dioxide is used and toluene is added. These conditions have the following favourable effects: (I) significant size reduction of ...

Energy Technology Data Exchange (ETDEWEB)

In response to the Clean Coal II solicitation, Bethlehem Steel Corporation (BSC) submitted a proposal to the DOE in May 1988. The proposal submitted by BSC describes a Unique integration of commercial technologies developed by Davy/Still Otto to clean coke oven gas being produced at its Sparrows Point, Maryland steel plant. This innovative coke oven gas cleaning system combines secondary gas cooling with hydrogen sulfide and ammonia removal, hydrogen sulfide and ammonia recovery, ammonia destruction and sulfur recovery to produce a cleaner fuel gas for plant use. The primary environmental benefit associated with employing this innovative coke oven gas cleaning system is realized when the fuel gas is burned within the steel plant. Emissions of sulfur dioxide are reduced by more than 60 percent. The removal, recovery and destruction of ammonia eliminates the disposal problems associated with an unmarketable ammonium sulfate by-product. ...

International Nuclear Information System (INIS)

In order to develop competitive and reliable nuclear power generation systems, development of innovative structural design methods is indispensable and risk-based design approach based on the assessment of failure probability is being developed. Fatigue is commonly considered as an important contributor to failure probability in many components of reactor systems and its assessment gives a large influence on total reliability of the plants. In order to assess its effect on the reliability, propagation of cracks needs to be evaluated as well as their initiation and pre-existence probability. As a part of new design approach, efforts are being taken to develop a simplified estimation method for fatigue crack growth under cyclic application of thermal and thermo-mechanical loading. A simplified estimation method of J-integral based on reference stress method and elastic follow-up factor was developed based on many finite element analyses and evaluation of crack growth ...

Science.gov (United States)

New tetradentate N(2)O(2) donor Schiff bases and their mononuclear Co(II), Ni(II), Cu(II), and Pd(II) complexes were synthesized and characterized extensively by IR, (1)H-, (13)C-NMR, mass, ESR, conductivity measurements, elemental and thermal analysis. Specifically the magnetic and electronic spectral measurements demonstrate the octahedral structures of cobalt(II), nickel(II) complexes and square planar geometries of copper(II), palladium(II) complexes. All the ligands and complexes were screened for their in vitro antibacterial activity against two gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus) and two gram-negative bacteria (Escherichia coli, Klebsiella pneumonia). In this study, Pd(II) complexes exhibited potent antibacterial activity against B. subtilis, S. aureus whereas ...

International Nuclear Information System (INIS)

... carbon 14 cholera gels labelling membranes molecules proteins receptors

KoreaScience (Korea)

Full Text Available

UK PubMed Central (United Kingdom)

Some acylhydrazine derived ONO donor Schiff bases and their Co(II) and Ni(II) complexes have been prepared having the same metal ion (cation) but different anions. These synthesized metal(II)...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The diffusion of alkali vapours in the anode compartment of a DIR-MCFC produces the deactivation of the internal reforming catalyst. Sets of ceramic porous membranes purposed to limit the diffusion have been manufactured by different techniques and the influence of the preparation technique and of the preparative variables on the morphological characteristics of the membranes structures has been studied.

Energy Technology Data Exchange (ETDEWEB)

This document provides stakeholder evaluations on innovative technologies to be used in the remediation of volatile organic compounds from soils and ground water. The technologies evaluated are; in-well vapor stripping, in-situ bioremediation, and gas membrane separation.

Energy Technology Data Exchange (ETDEWEB)

Water transport in the ionomeric membrane, typically Nafion{reg_sign}, has profound influence on the performance of the polymer electrolyte fuel cell, in terms of internal resistance and overall water balance. In this work, high resolution neutron imaging of the Nafion{reg_sign} membrane is presented in order to measure water content and through-plane gradients in situ under disparate temperature and humidification conditions.

UK PubMed Central (United Kingdom)

A structurally conserved element, the trigger loop, has been suggested to play a key role in substrate selection and catalysis of RNA polymerase II (pol II) transcription elongation. Recently resolved...Full Text Available

UK PubMed Central (United Kingdom)

DNA from the peripheral blood mononuclear cells of 17 different individuals infected with human T-cell lymphoma/leukemia virus type II (HTLV-II) was successfully amplified by the polymerase chain reaction...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

The development of calcium sulfate dihydrate (gypsum) mineral scale in reverse osmosis (RO) membrane desalting was investigated by direct real-time observation of crystal growth. Gypsum scaling studies were conducted in a specially modified plate-and-frame reverse osmosis cell fitted with an optical window, with dark-field membrane lighting arrangement within the membrane cell to enhance crystal boundaries and allow recording of digital surface images magnified through an optical microscope. The evolution of the surface number density (SND) of gypsum crystals resembled a sigmoidal population growth process with an increasing rate of crystal formation at higher solution supersaturation (with respect to gypsum) at the membrane surface. The rate of formation of new crystals declined as the su...

Energy Technology Data Exchange (ETDEWEB)

Since artificial organs are intended to replicate chemical processes, knowledge of chemical engineering is essential in their design so that they will function with the maximum efficiency. The most commonly used artificial organ is the artificial kidney, a machine that performs a treatment known as hemodialysis. This process cleanses the bodies of renal failure patients by dialysis and filtration which are simple physiochemical processes. Hemodialysis membranes act to remove accumulated uremia toxins, excess ions and water from the patient via the dialysate, and to supply from the dialysate those ions that are insufficient. This paper describes dialysis membranes and dialyzers for blood purification, the solute transport mechanism of the membrane, and a technical evaluation of the dialysis membrane. Lastly, the next generation of artificial kidney is reviewed. 71 refs., 12 figs., 7 tabs.

British Library Electronic Table of Contents (United Kingdom)

Several thin film composite nanofiltration membranes have been prepared by spin coating a sulfonated poly(ether ether ketone) solution on a polyethersulfone support, followed by thermal treatment. The most optimal developed nanofiltration membrane shows a clean water permeance of ~4.5Lm^-^2h^-^1bar^-^1 and a molecular weight cut off (MWCO) of ~500gmol^-^1. No irreversible changes in membrane performance have been observed after prolonged exposure (up to several weeks) of this membrane to solutions with a pH in the range 0-14. Compared to Desal-5-DK, the developed membrane displays a similar water permeance and a higher NaCl retention. In comparison to commercially available pH stable membranes, MPF-34 and NP030P, it reveals a higher water permeance. Permeance and MWCO analysis at varying p...

Energy Technology Data Exchange (ETDEWEB)

The in situ assembly states of the glucose transport carrier protein in the plasma membrane and in the intracellular (microsomal) storage pool of rat adipocytes were assessed by studying radiation-induced inactivation of the D-glucose-sensitive cytochalasin B binding activities. High energy radiation inactivated the glucose-sensitive cytochalasin B binding of each of these membrane preparations by reducing the total number of the binding sites without affecting the dissociation constant. The reduction in total number of binding sites was analyzed as a function of radiation dose based on target theory, from which a radiation-sensitive mass (target size) was calculated. When the plasma membranes of insulin-treated adipocytes were used, a target size of approximately 58,000 daltons was obtained. For adipocyte microsomal membranes, we obtained target sizes of approximately 112,000 and 109,000 daltons prior ...

International Nuclear Information System (INIS)

Two methods were used to label pig kidney microvillar membrane proteins from the luminal and cytoplasmic surfaces of closed membrane vesicles. The first method was lactoperoxidase-catalysed radioiodination. Lactoperoxidase and glucose oxidase were positioned inside or outside the vesicles, iodination being initiated by adding glucose and "1"2"5I. After electrophoresis of the proteins, asymmetric labelling patterns on radioautographs were observed. However the major disadvantage of this method was the high degree of intramembrane labelling of the fatty acid chains of membrane lipids. The second method overcame this disadvantage. A new hydophilic photoreagent, 3,5-di("1"2"5I)iodo-4-azidobenzenesulphonate, was transported by a Na"+-dependent system into microvillar vesicles, thus permitting labelling from either side of the membrane when the vesicles were photolysed. The activity of several microvillar ...

Science.gov (United States)

The results of this research centered on the experimental studies of a single superconducting persistent current qubit, the implementation of type-II algorithms using these qubits, and the proposal for adiabatic quantum computing using these qubits. The m...

UK PubMed Central (United Kingdom)

The in vivo photochemical activity of photosystem II was inferred from modulated chlorophyll fluorescence and photoacoustic measurements in intact leaves of several plant species (Lycopersicon...Full Text Available

UK PubMed Central (United Kingdom)

Woolfolk, C. A. (University of Washington, Seattle). Reduction of inorganic compounds with molecular hydrogen by Micrococcus lactilyticus. II. Stoichiometry with inorganic...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This document describes payload control at LLNL to ensure that all shipments of CH-TRU waste in the TRUPACT-II (Transuranic Package Transporter-II) meet the requirements of the TRUPACT-II SARP (safety report for packaging). This document also provides specific instructions for the selection of authorized payloads once individual payload containers are qualified for transport. The physical assembly of the qualified payload and operating procedures for the use of the TRUPACT-II, including loading and unloading operations, are described in HWM Procedure No. 204, based on the information in the TRUPACT-II SARP. The LLNL TRAMPAC, along with the TRUPACT-II operating procedures contained in HWM Procedure No. 204, meet the documentation needs for the use of the TRUPACT-II at LLNL. Table 14-1 provides a summary of the LLNL waste generation and ...

Energy Technology Data Exchange (ETDEWEB)

Biosorption using activated sludge biomass (ASB) as a potentially sustainable technology for the treatment of wastewater containing different metal ions (Cd(II), Pb(II) and Zn(II)) was investigated. ASB metal uptake clearly competed with protons consumed by microbial biomass compared with control tests with non-activated sludge biomass. Biosorption tests confirmed maximum exchange between metal ions and protons at pH 2.0-4.5. It was revealed by the study that the amount of metal ions released from the biomass increased with biomass sludge concentration. The result showed that maximum absorption of metal ions was observed for Cd(II) at pH 3.5, Pb(II) at pH 4.0, and pH 4.5 for Zn(II) ions. The maximum absorption capacities of ASB for Cd(II), Pb(II) and Zn(II) were determined to be 59.3, 68.5 and 86.5%, ...

International Nuclear Information System (INIS)

The p75 neurotrophin receptor (p75"N"T"R) is a death receptor which belongs to the tumor necrosis factor receptor super-family of membrane proteins. This study shows that p75"N"T"R retarded cell cycle progression by induced accumulation of cells in G0/G1 and a reduction in the S phase of the cell cycle. The rescue of tumor cells from cell cycle progression by a death domain deleted (#DELTA#DD) dominant-negative antagonist of p75"N"T"R showed that the death domain transduced anti-proliferative activity in a ligand-independent manner. Conversely, addition of NGF ligand rescued retardation of cell cycle progression with commensurate changes in components of the cyclin/cdk holoenzyme complex. In the absence of ligand, p75"N"T"R-dependent cell cycle arrest facilitated an increase in apoptotic nuclear fragmentation of the prostate cancer cells. Apoptosis of p75"N"T"R expressing cells occurred via the intrinsic mitochondrial pathway leading to a sequential caspase-9 and ...

Energy Technology Data Exchange (ETDEWEB)

The purified integral membrane protein, band 3, from human erythrocytes was inserted into egg lecithin liposomes. The insertion of band 3 was determined from thermal transition data from the analysis of the C-H stretching region bands recorded at temperatures from 25 to -22[sup o]C. Raman spectra show that band 3 considerably broadens and lowers the thermal transition of egg lecithin liposomes, suggesting the insertion of band 3. The band 3-inserted liposomes were irradiated with gamma-rays (40 Gy) and the radiation target groups were determined by the analysis of the structural sensitive Raman bands in the 1600-1700 cm[sup -1] (amide I), 1200-1300 cm[sup -1] (amide III) and 550-1030 cm[sup -1] (side chain amino groups) regions. The radiation-sensitive groups as identified from Raman spectra in the region 550-1030 cm[sup -1] are tyrosines and cysteines. The radiation-induced changes in the secondary structure were determined from amide I and ...

Energy Technology Data Exchange (ETDEWEB)

Coal may be used to generate electrical energy by any of several processes, most of which involve combustion or gasification. Combustion in a coal-fired boiler and power generation using a steam- cycle is the conventional conversion method; however, total energy conversion efficiencies for this type of process are only slightly over 30{percent}. Integration of a gas-cycle in the process (combined cycle) may increase the total conversion efficiency to 40{percent}. Conversion processes based on gasification offer efficiencies above 50{percent}. H{sub 2}S is the predominant gaseous contaminant in raw coal gas. Problems arise due to the corrosive nature of H{sub 2}S on metal components contained in these cycles. Because of this, H{sub 2}S concentrations must be reduced to low levels corresponding to certain power applications. An advanced process for the separation of hydrogen sulfide (H{sub 2}S) from coal gasification product streams through an electrochemical ...

Science.gov (United States)

... MTR 93B0000095 Proposed Network Security Policy for Integrated Tactical Warning ... Proposed Network security Policy for Integrated Tactical ...

Energy Technology Data Exchange (ETDEWEB)

This dissertation is concerned with the development, experimental diagnostics and mathematical modelling and simulation of polymer electrolyte fuel cells (PEFC). The central themes throughout this thesis are the closely interlinked phenomena of mass and charge transfer. In the face of developing a PEFC system for vehicle propulsion these phenomena are scrutinized on a broad range of relevant scales. Starting from the material related level of the membrane and the gas diffusion layer (GDL) we turn to length scales, where structural features of the cell additionally come into play. These are the scale of flow channels and ribs, the single cell and the cell stack followed by the cell, stack, and system development for an automotive power train. In Chapter 3 selected fundamental material models and properties, respectively, are explored that are crucial for the mathematical modelling and simulation of PEFC, as needed in some succeeding parts of this work. First, ...

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Energy Technology Data Exchange (ETDEWEB)

Short communication.

Energy Technology Data Exchange (ETDEWEB)

The biomedical and ecological interest for the microwave impact on the Earth biosphere is continuously increased since the industrial, military and communication activities strongly contribute to the electromagnetic stress of living bodies. In the next the authors present some of the main results obtained regarding the microwave exposure of various types of biological material: bacteria, fungi, young plant seedlings, dry seeds, animal tissues. The electromagnetic exposure was carried out in open space in well controlled environmental conditions by using 10.75 GHz/1 m W cm{sup -2} microwaves. Biochemical assays and cytogenetic tests have been carried out to reveal the changes induced post irradiation. The response of some pathogen bacteria, have been emphasized by means of turbidimetric measurements - the stimulatory effect being noticed at the level of the microbial population density (the stimulation of the human body microbial flora seems to be one of the side effects of microwave ...

Energy Technology Data Exchange (ETDEWEB)

Short communication. 5 refs., 2 figs.

International Nuclear Information System (INIS)

... momentum transfer propagator scattering scattering amplitudes strong

Energy Technology Data Exchange (ETDEWEB)

Apart from the vulnerability implied by the START II treaty, it will bear the burden of the general political opposition to the Yeltsin administration. START II will be seen as part of an overall Yeltsin-Andrei Kozyrev foreign policy that is under fire for selling out Russian national interests in Yugoslavia, the Persian Gulf, and elsewhere. This article discusses public opinion concerning START II, the cost of its implementation, and the general purpose of the treaty.

Energy Technology Data Exchange (ETDEWEB)

The upgraded CDF II detector has collected first data during the initial operation of the Tevatron accelerator in Run II. The simulation of the CDF electromagnetic and hadronic central and upgraded plug (forward) calorimeter is based on the Gflash calorimeter parameterization package used within the GEANT based detector simulation of the Run II CDF detector. We present the results of tuning the central and plug calorimeter response to test beam data.

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Energy Technology Data Exchange (ETDEWEB)

The purpose of this paper is to describe the embedded computer systems approach taken at Experimental Breeder Reactor II (EBR-II) for non-safety related systems. The hardware and software structures for typical embedded systems are presented The embedded systems development process is described. Three examples are given which illustrate typical embedded computer applications in EBR-II.

KoreaScience (Korea)

Full Text Available

Science.gov (United States)

PMID:10226312

Science.gov (United States)

The requirements for successful integration of a computer aided control system for multi degree of

Science.gov (United States)

... Page 43. Integrated Audio Technology Demonstrator The Integrated Audio Technology Dem- development for this application is successful. ...

Science.gov (United States)

Water transport in conifers occurs through single-celled tracheids that are connected to one another via intertracheid pit membranes. These membranes have two components: the porous margo, which allows water to pass through the membrane, and the impermeable torus, which functions to isolate gas-filled tracheids. During drought, tracheids can become air filled and thus hydraulically dysfunctional, a result of air entering through the pit membrane and nucleating cavitation in the water column. What are the hydraulic tradeoffs associated with cavitation resistance at the pit level, and how do they vary within the structural components of the intertracheid pit? To address these questions, we examined pit structure in 15 species of Cupressaceae exhibiting a broad range of cavitation resistances. Across species, cavitation resistance was most closely correlated to the ratio of the torus to pit aperture ...

International Nuclear Information System (INIS)

The PERMCAT process chosen for the final clean-up stage of the Tokamak Exhaust Processing system of the ITER tritium plant combines in a single component a catalytic reactor and a permeator using Pd/Ag membranes. This study covers the mechanical behaviour of a Pd/Ag membrane under different operating conditions. The consequences of hydrogen uptake by the membrane during nominal operation but also during off-normal events are presented. Depending on the operating conditions, expansions around 2% and significant deformations are observed. Different mechanical designs of PERMCAT reactors are then discussed. The first generation comprises finger-type membranes and two new mechanical designs use either additional edge welded bellows or a special corrugated Pd/Ag membrane. These upgraded designs improve the robustness and simplify the geometry of the component. The experimental validation ...

Energy Technology Data Exchange (ETDEWEB)

An evaporator using a hydrophobic membrane made from a polytetrafluoroethylene (PTFE) was developed to improve DF (Decontamination Factor) and to reduce evaporator size. The membrane distillation, provided by the evaporator, is a new technique for liquid purification. Fundamental experiments were carried out to develop the membrane filter (tube type, outer diameter, 8 mm; membrane thickness, 500 {mu}m) for radioactive liquid treatment. The continuous operation test using actual liquid waste was also made during about 3,000 h. (This is almost equal to the operation time of an actual evaporator per year.) The evaporation rate decreased with increase an operation time due to contamination of waste impurity. But the rate was recovered by washing the membrane with hot water and then drying it. DF was over 10{sup 4} which is ten times larger than that for a conventional system. A pilot ...

Energy Technology Data Exchange (ETDEWEB)

We study the static potential of open bosonic membranes in the 1/d approximation, where d is the space-time dimensionality. For a fixed square boundary of side length R we find, in contrast to the string potential, no critical distance below which tachyons appear. Instead, we find a correction factor to the classical potential, V/sub cl/=kR/sup 2/, which for small distances shifts the perturbative ground state energy by a positive constant. We interpret the shift as the mass gap of this quantum membrane.

International Nuclear Information System (INIS)

The analgesic, dipyrone (1,phenyl-2,3-dimethyl-5-pyrazolone-4-methylamino methane sulphonate sodium), at 20 mM concentration, inhibited the rejoining of single-strand scissions in DNA of Escherichia coli B/r cells induced by 20 krad gamma-radiation. The chemical altered the cell membrane structure as evidenced from the uptake of acriflavin, the efflux of potassium ions from the bacterial cells and the inhibition of alkaline phosphatase-a cell membrane associated enzyme. (author).

Energy Technology Data Exchange (ETDEWEB)

This paper proposes an integrated method for using experimental data and CFD modeling to develop engineering correlations for atrium smoke management. Part I focused on the experimental program and validation of a CFD model of the experimental facility. Part II describes the extension of this model to a parametric study of balcony spill plumes. Smoke management in buildings during fire events often uses mechanical ventilation systems to maintain smoke layer elevation above a safe evacuation path. Design of these systems requires accurate correlations for the smoke production or mass flow rate of the buoyant fire plume. One design issue is the mass flow rate of fire plumes which spill out from a fire compartment, under a balcony and up through an atrium or other large volume. Current engineering correlations for these balcony spill plumes (BSPs) are based on a combination of one-tenth scale test data and theoretical analysis. The suitability of ...

Science.gov (United States)

Nitrate microelectrodes and ORP microelectrodes were fabricated to study the denitrification characteristics of dynamic membrane at different COD loadings. The denitrification process was found at 0.6-1 mm depth beneath the interface of biofilm/bulk. The results of ORP microelectrode also demonstrated that the ORP value in the range of denitrification area was between 88.6 approximately -128.4 mV which was appropriate to denitrification. When the COD loading was 0.45 kg/(m3 x d), the denitrification rate (NO3- -N) was the maximum of 0.6347 x 10(-6 mol/(L x s). With the increase of COD loading, the denitrification area was increasing and two layers with different denitrification rates emerged in the dynamic membrane. The phenomenon implied the effect of organic concentration, oxygen concentration and bacterial competition on the denitrification rate. PMID:17117632

Energy Technology Data Exchange (ETDEWEB)

A study was made of the uncoupling action of polychlorinated biphenyls (Kanechlor-400) on oxidative phosphorylation in rat liver mitochondria. Kanechlor-400 (KC-400) at 20 ..mu..g/ml stimulated state 4 respiration of rat liver mitochondria more than 4-fold with ..cap alpha..-ketoglutarate/malate as a substrate, and released the oligomycin-inhibited state 3 respiration. KC-400 also dissipated the membrane potential across the mitochondrial membranes; thus, it acts as an uncoupler of oxidative phosphorylation in rat liver mitochondria. KC-400 altered the permeability properties of mitochondrial membranes as evidenced by the release of endogenous K/sup +/ and the oxidation of exogenously supplied NADH. It is concluded that KC-400 produces a nonspecific increase in mitochondrial ion permeability, thereby dissipating membrane potential, which leads to the uncoupling.

UK PubMed Central (United Kingdom)

BackgroundWith the exception of vertebrates, most organisms have plasma membrane associated ammonium transporters which primarily serve to import a source of nitrogen for nutritional...Full Text Available

UK PubMed Central (United Kingdom)

Decreased membrane rigidity is one of the characteristics of malignant cells, resulting in part from the desaturation of stearic acid into oleic acid. In this study we investigated the influence of...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

A novel composite charged mosaic membrane (CCMM) was prepared via interfacial polymerization (IP) of polyamine [poly(epichlorohydrin amine)] and trimesoyl chloride (TMC) on the polyethersulfone (PES) support. Fourier transform infrared spectroscopy (FT-IR), environmental scanning electron microscopy (ESEM), atomic force microscopy (AFM) and water contact angle analysis were applied to characterize the resulted CCMM. The FT-IR spectrum indicates that TMC reacts sufficiently with polyamine. ESEM and AFM pictures show that the IP process produces a dense selective layer on the support membrane. The water contact angle of the CCMM is smaller than that of the substrate membrane because of the cross-linked hydrophilic polyamine network. Several factors affecting the IP reaction and the performan...

British Library Electronic Table of Contents (United Kingdom)

A dense Pd-Ag membrane reactor (MR) with 100% hydrogen selectivity packed with either Rh/La2O3 or Rh/La2O3-SiO2 as catalysts was used to carry out the dry reforming of methane. The membrane reactor simulation was performed using a well-known reactor model. For this purpose, we employed the equations derived from complete kinetic studies of the dry reforming of methane reaction in connection with both catalysts. In addition, we developed the kinetic equation for the reverse water gas shift reaction (RWGS). The combination of detailed kinetic studies with the measured permeation flux for the Pd-Ag membrane allowed a complete comparison between experimental and simulated operation variables. The variables studied for both catalysts were methane conversion and hydrogen permeation as a function...

UK PubMed Central (United Kingdom)

Gangliosides are amphiphilic molecules found in the outer layer of plasma membranes of all vertebrate...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Certain allelochemicals of the marine dinoflagellate Alexandrium tamarense cause lysis of a broad spectrum of target protist cells but the lytic mechanism is poorly defined. We first hypothesized that membrane sterols serve as molecular targets of these lytic compounds, and that differences in sterol composition among donor and target cells may cause insensitivity of Alexandrium and sensitivity of targets to lytic compounds. We investigated Ca^2^+ influx after application of lytic fractions to a model cell line PC12 derived from a pheochromocytoma of the rat adrenal medulla to establish how the lytic compounds affect ion flux associated with lysis of target membranes. The lytic compounds increased permeability of the cell membrane for Ca^2^+ ions even during blockade of Ca^2^+ channels wit...

British Library Electronic Table of Contents (United Kingdom)

In situ synthesis of silver chloride (AgCl) nanoparticles was carried out under ambient conditions in nanoporous bacterial cellulose (BC) membranes as nanoreactors. The growth of the nanoparticles was readily obtained by alternating dipping of BC membranes in the solution of silver nitrate or sodium chloride followed by a rinse step. X-ray diffraction (XRD) patterns indicated the existence of AgCl nanoparticles in the BC and scanning electron microscopy (SEM) images showed that the AgCl nanoparticles well dispersed on the surface of BC and penetrated into the BC network. The AgCl nanoparticle-impregnated BC membranes exhibited high hydrophilic ability and strong antimicrobial activity against Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive). The preparative proced...

UK PubMed Central (United Kingdom)

Hyaluronan is a multifunctional glycosaminoglycan that forms the structural basis of the pericellular matrix. Hyaluronan is extruded directly through the plasma membrane by one of three hyaluronan...Full Text Available

International Nuclear Information System (INIS)

In the present study the authors have shown that glycoproteins are present in the plasma membrane of Acanthamoeba castellanii by utilizing different radioactive labeling techniques. Plasma membrane proteins in the amoeba were iodinated by "1"2"5I-lactoperoxidase labeling and the solubilized radiolabeled glycoproteins were separated by lectin-Sepharose affinity chromatography followed by polyacrylamide gel electrophoresis. The periodate/NaB"3H_4 and galactose oxidase/NaB"3H_4 labeling techniques were used for labeling of surface carbohydrates in the amoeba. Several surface-labeled glycoproteins were observed in addition to a diffusely labeled region with M_r of 55,000-75,000 seen on electrophoresis, which could represent glycolipids. The presence of glycoproteins in the plasma membrane of Acanthamoeba castellanii was confirmed by metabolic labeling with ["3"5S]methionine followed by lectin-Sepharose affinity chromatography ...

British Library Electronic Table of Contents (United Kingdom)

Functional properties of commercial and membrane processed pea protein isolates (PPI) prepared from yellow peas were investigated. Four protein isolates were prepared from yellow pea flour using water and KCl extractions at 25^oC followed by ultrafiltration and diafiltration (UF and DF) at pHs of 7.5 and 7.5 or 6 respectively. Following assessment of compositional attributes; solubility, foaming, flow and dynamic rheology, emulsification ability and heat-induced textural and rheological properties of prepared PPIs and a commercially available PPI were tested and compared. Membrane purification of proteins resulted in 28% to 68% reduction in phytic acid and enhanced, comparatively, the tested functional properties. Solubility of membrane processed PPIs, at all tested pHs, was superior and t...

UK PubMed Central (United Kingdom)

AMPA receptors (AMPARs) are critical for synaptic plasticity, and are subject to alterations based on subunit composition and receptor trafficking to and from the plasma membrane. One of the...Full Text Available

UK PubMed Central (United Kingdom)

Symmetrical, extracellular fibrils, which are related to the "special fibrils" of the dermis described by Palade and Farquhar, have been found along the outer surface of the basement membrane covering...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Adsorptive removal of Pb(II) ions from aqueous solution onto a non-activated charcoal (CC) of oak wood origin was studied in comparison with an activated carbon of coal origin. The adsorption capacity for Pb(II) of the non-activated charcoal increased significantly with deceasing particle diameter, whereas the activated carbon (AC) exhibited approximately constant capacity for Pb(II) adsorption as a function of particle size. Adsorption to the ashes prepared from the non-activated charcoal and the activated carbon was also investigated to examine the role of mineral ash. Although the ash from the activated carbon did not show any Pb(II) adsorption, the ash from the charcoal was very effective for Pb(II) adsorption. Furthermore, Pb(II) was hardly adsorbed when the ash was removed from the non-activated charcoal by acid treatment. Based on the results, the ...

Energy Technology Data Exchange (ETDEWEB)

For heavy-ion beam driven inertial fusion ''liquid-protected'' reactor designs such as HYLIFE-II, a mixture of molten salts made of F{sup 10}, Li{sup -6}, Li{sup 7} and Be{sup 9} (called flibe) allows small chambers and final-focus magnets closer to the target with superconducting coils suffering higher radiation damage, though they can stand only a certain amount of energy deposited before quenching. This work has been primarily focusing on verifying that total energy deposited by fusion neutrons and induced gamma rays remain under such limit values and the final purpose is the optimization of the shielding of the magnetic lens system from the points of view of the geometrical configuration and of the physical nature of the materials adopted. The system is analyzed in terms of six geometrical models going from simplified up to much more realistic representations of a system of 192 beam lines, each focused by six magnets. A 3-D ...

Energy Technology Data Exchange (ETDEWEB)

Biological motors generally fall into two categories: (1) those that convert chemical into mechanical energy via hydrolysis of a nucleoside triphosphate, usually adenosine triphosphate, regarded as life's chemical currency of energy and (2) membrane bound motors driven directly by an ion gradient and/or membrane potential. Here we argue that electrostatic interactions play a vital role for both types of motors and, therefore, the tools of physics can greatly contribute to understanding biological motors.

International Nuclear Information System (INIS)

Two different reverse osmosis systems were investigated. The first was a 50-element plant-scale system that is used to treat 2200 m"3 of AECL liquid radwastes annually.It uses thin-film composite (TFC) membranes and operates at an applied pressure of 2760 kPa, with a fixed crossflow of about 40 L/min. The other system uses the same thin-film composite membranes for waste processing but is a two-element pilot-scale system. It is operated at pressures m ranging between 1500 and 7000 kPa, at a fixed crossflow of 55 L/min. The average lifetime of the thin-film composite membranes in the plant-scale processing application at AECL is about 3000 h. After this service life has expired the rejection efficiency declines rapidly from 99.5% to about 95% as the membranes become impaired from chemical cleaning procedures that are required after each 100 m"3 of waste is treated. The permeation flux for the plant-scale ...

UK PubMed Central (United Kingdom)

During apoptosis, the pro-apoptotic Bcl-2 family proteins BAK and BAX form large oligomeric pores in the mitochondrial outer membrane. Apoptotic factors, including cytochrome c, are...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

We perform a recursive reduction of one-loop n-point rank R tensor Feynman integrals [in short: (n,R)-integrals] for n{<=}6 with R{<=}n by representing (n,R)-integrals in terms of (n,R-1)- and (n-1,R-1)-integrals. We use the known representation of tensor integrals in terms of scalar integrals in higher dimension, which are then reduced by recurrence relations to integrals in generic dimension. With a systematic application of metric tensor representations in terms of chords, and by decomposing and recombining these representations, we find the recursive reduction for the tensors. The procedure represents a compact, sequential algorithm for numerical evaluations of tensor Feynman integrals appearing in next-to-leading order contributions to massless and massive three- and four-particle production at LHC and ...

Energy Technology Data Exchange (ETDEWEB)

The authors have interpreted 1,400 km of industry and government multichannel seismic reflection data from eastern Lake Superior. Seismic sequences have been identified by using reflection character and reflector terminations and truncations. This framework, coupled with outcrop information, has allowed them to assign lithologic units to some of these reflectors and reconstruct the timing and geometry of structures within the basin. The authors have mapped the Base Jacobsville-Bayfield Group/Top oronto Group, Base oronto Group/Top Keweenawan volcanics, and Basement as well as several reflectors internal to these groups. Integration of gravity and magnetic data with the seismic grid permits regional mapping of faults and folds between seismic lines. In the eastern part of the basin, high-angle basement-involved reverse faults, such as the southeastern combination of the Keweenaw fault, trend NNW-SSE, while broad folds trend E-W. The Keweenaw fault is a complex ...

Energy Technology Data Exchange (ETDEWEB)

In 2004, the Southeastern France regional council asked the regional health observatory to conduct an environmental health inventory to i) identify environmental health problems in this area; ii) examine the relations between environmental exposure to pollutants and human health; and iii) help public officials to identify priorities in this area. We collected and validated data from national, regional and local institutions, constructed environmental (levels of emissions and pollutants), health (mortality, incidence, prevalence) and behavioral indicators (e.g., complaints about odors), and compared these over time and between places when possible. For each topic, we summarized current knowledge about the links between environment and health. In southeastern France, as in other French areas, indoor air pollution, home and leisure injuries and other home-related risks are public health issues. Other topics are more significant or particular to southeastern France: ...

Energy Technology Data Exchange (ETDEWEB)

This thesis presents measurements of inelastic photoproduction and electroproduction of J/{psi} mesons in ep scattering at HERA. The data was collected by the H1 detector during the HERA II running and corresponds to an integrated luminosity of L {approx} 166 pb{sup -1} in the photoproduction analysis and L {approx} 315 pb{sup -1} in the electroproduction analysis. In both analyses the elasticity of the J/{psi} meson is restricted to a medium range of 0.3 {<=} z {<=} 0.9. The kinematic range of the photoproduction analysis is defined by Q{sup 2} {approx} 0 GeV{sup 2}, 60 {<=}W{sub {gamma}}{sub p}{<=} 240 GeV and P{sub {tau}}{sub ,{psi}}{>=} 1 GeV{sup 2}, whereas the electroproduction analysis is restricted to 3.6 {<=} Q{sup 2} {<=} 100 GeV{sup 2}, 50 {<=}W{sub {gamma}}{sub p}{<=} 225 GeV, and P{sup *}{sub {tau}}{sub ,} {sub {psi}} {>=} 1 GeV. Here P{sup *}{sub {tau}}{sub ,} ...

Energy Technology Data Exchange (ETDEWEB)

The samples comprise the foliage of four pteridosperm-medullosalean plant fossil species of differing preservation states and one of a cordaitean species from two Canadian Maritime sub-basins of Carboniferous age (300 Ma; Sydney and Stellarton coalfields, Nova Scotia, respectively). Included in the sample set were some coal samples from Sydney Coalfield, along with published data for coal macerals for comparison. By applying Schulze's maceration process to the fossil foliage to obtain the cuticles, five sample forms evolved, viz. compressions, cuticles and fossilized cuticles, and acidic and alkaline solutions from Schulze's process, to which was added the Sydney coal samples as the sixth form. Area integration of the absorbance spectra from solid and liquid state Fourier transform infrared (FTIR) spectroscopy, produced functional chemical parameters which were organized into a data matrix of eight variables and 62 samples (8 x 62 matrix). ...

Science.gov (United States)

The goal of the present study is to elucidate the effect of lipid domain formation on activities of Naja naja atra and Bungarus multicinctus phospholipase A(2) (PLA(2)) enzymes. Sphingomyelin inhibited enzymatic activity and membrane-damaging activity of PLA(2) against egg yolk phosphatidylcholine (EYPC), while cholesterol and cholesterol sulfate abrogated the inhibitory effect of sphingomyelin. The ability of cholesterol and cholesterol sulfate to abolish the inhibitory effect of sphingomyelin was closely related to their capacity to induce domain formation in EYPC/sphingomyelin vesicles. Laurdan fluorescence measurement revealed that membrane packing of EYPC/sphingomyelin vesicles was differently affected by cholesterol and cholesterol sulfate. Unlike cholesterol, cholesterol sulfate was unable to promote domain formation in dipalmitoylphosphatidylcholine (DPPC) vesicles. Cholesterol increased but cholesterol sulfate reduced PLA(2) activity ...

Energy Technology Data Exchange (ETDEWEB)

A new organic-inorganic hybrid membrane has been prepared with exceptional performance in dewatering applications. The only precursor used in the sol-gel synthesis of the selective layer was organically linked 1,2-bis(triethoxysilyl)ethane (BTESE). The microporous structure of this layer enables selective molecular sieving of small molecules from larger ones. In the dehydration of n-butanol with 5% of water, the membrane shows a high separation factor of over 4000 and ultra-fast water transport at a rate of more than 20 kg m{sup -2} h{sup -1} at 150C. This can be related to the high adsorption capacity of the material and the sub-micron thickness of the selective layer. The selectivity has now remained constant over almost one and a half years under continuous process testing conditions. Apart from the hydrothermal stability, the membrane exhibits a high tolerance for acid contamination. A slow performance decline in flux ...

Energy Technology Data Exchange (ETDEWEB)

This document presents the integrated reactors concepts by a presentation of four reactors: PIUS, SIR, IRIS and CAREM. The core conception, the operating, the safety, the economical aspects and the possible users are detailed. From the performance of the classical integrated PWR, the necessity of new innovative fuels utilization, the research of a simplified design to make easier the safety and the KWh cost decrease, a new integrated reactor is presented: SCAR 600. (A.L.B.)

Energy Technology Data Exchange (ETDEWEB)

The advent of sophisticated automation equipment and computer hardware and software is changing the way manufacturing is carried out. To compete in the global marketplace, manufacturing companies must integrate these new technologies into their factories. In addition, they must integrate the planning, control, and data management methodologies needed to make effective use of these technologies. This paper provides an overview of recent approaches to achieving this enterprise integration. It then describes, using simulation as a particular example, a new tool`s perspective of enterprise integration.

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

UK PubMed Central (United Kingdom)

ObjectivesThe updated Rome III criteria for pediatric functional gastrointestinal disorders (FGIDs) include new FGID categories and changes to the Rome II criteria...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

UK PubMed Central (United Kingdom)

Aminopeptidase II, one of the two major aminopeptidases in the giant alga Chara australis, was partially purified. Its molecular weight was estimated to be about 80,000 by gel permeation...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Energy Technology Data Exchange (ETDEWEB)

The aim of this article was to investigate the interactions of metal cations in aqueous solutions with the biomass of the freshwater macroalga Vaucheria sp. This problem is important when elaborating new applications of biosorption, e.g. the production of mineral feed additives for livestock from the biomass of algae enriched with microelement ions. Potentiometric titration was applied as a quick and cheap screening test to search for new efficient biosorbents. It revealed a variety of functional groups capable of cation exchange on the macroalgal surface, including carboxyl, phosphate, hydroxyl or amino groups. Fourier transform infrared spectroscopy on natural and chromium-loaded Vaucheria sp. confirmed that carboxyl groups played a dominant role in the biosorption. The study also showed that Ca(II), Na(I), K(I), and Mg(II) ions were released from the biomass after biosorption of Cu(II), Mn(II), ...

UK PubMed Central (United Kingdom)

Rotazyme II, which is a shorter version of Rotazyme (less than 3 h), was compared with electron microscopy and Rotazyme for sensitivity and specificity on 229 human stool specimens. Compared with electron...Full Text Available

UK PubMed Central (United Kingdom)

ATP-binding cassette A3 (ABCA3) is a lipid transport protein required for synthesis and storage of pulmonary surfactant in type II cells in the alveoli. Abca3 was conditionally deleted...Full Text Available

UK PubMed Central (United Kingdom)

Cytokinesis in animal and fungal cells utilizes a contractile actomyosin ring (AMR). However, how myosin II is targeted to the division site and promotes AMR assembly, and how the AMR coordinates with...Full Text Available

UK PubMed Central (United Kingdom)

Photobilirubin II, a stereoisomer of bilirubin, binds to human serum albumin at a single binding site (K = 2.2 x 10(6)M-1), presumably the high-affinity bilirubin-binding site. Binding in the secondary...Full Text Available

Wastenet

ii) Flammability: (iii) A capacity to oxidise: (iv) Corrosiveness: (v) Toxicity (including chronic ...an explosion or fire: (d) For substances with corrosive properties: (i) To reduce the ...likelihood of any unintended corrosion:(ii) To control the adverse effects of any corrosion:

Science.gov (United States)

... Screening Adjudication Monitoring Applicants of Information Behavior II I Conducting Investigations ... Applicants of Information Behavior Conducting ...

KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Science.gov (United States)

... laser structure. However, still the greater part (60%) of emitted photons is a result of a spontaneous radiation process. In ...

Science.gov (United States)

... Accession Number : AD0833945. Title : COST EVALUATION AND COST ESTIMATING FOR SHIPBOARD ELECTRONIC EQUIPMENT. VOLUME II. ...

Science.gov (United States)

The interaction between N-donor adsorbates such as ammonia and pyridine with Cu(II)-exchanged montmorillonite, beidellite, flourohectorite into smectite clays has been studied by electron spin resonance. Cu(II) cations exchanged into smectites coordinate five ammonia or pyridine molecules in beidellite, four ammonia of pyridine molecules in hydroxyhectorite. Thus, the Cu(II) cations bound to the interior surfaces of these smectite clays constitute strong Lewis acid sites. 26 refs., 7 figs., 1 tab.

KoreaScience (Korea)

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Science.gov (United States)

In this paper, the following topics are studied: uranium 238 effective integral; thermal range uranium 238 capture cross section; Americium 242 m capture cross section. The mentioned examples show that differential and integral experiments are both useful...

Science.gov (United States)

We report the of the existence of RV Tauri stars in the Large Magellanic Cloud (LMC). This class of variable star has hitherto been unidentified in the Magellanic Clouds. In light and color curve behavior the RV Tauri stars appear to be an extension of the Type II Cepheids to longer periods. A single period-luminosity-color relationship is seen to describe both the Type II Cepheids and the RV Tauri stars in the LMC.

UK PubMed Central (United Kingdom)

Fatty acid biosynthesis is crucial for all living cells. In contrast to higher organisms, bacteria use a type II fatty acid synthase (FAS II) composed of a series of individual proteins, making...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Science.gov (United States)

... Infantry Division A Monograph by ... 5b. GRANT NUMBER 4. TITLE AND SUBTITLE Integration of Armored Forces in the US Army Infantry Division ...

UK PubMed Central (United Kingdom)

PurposeDescription and analysis of the effects and side-effects of integrated mental health care in the Netherlands.Context of caseDue...Full Text Available

International Nuclear Information System (INIS)

We have successfully incorporated high surface area particles of titanate ion exchange materials (monosodium titanate and crystalline silicotitanate) with acceptable particle size distribution into porous and inert support membrane fibrils consisting of polytetrafluoroethylene (Teflon(reg_sign)), polyethylene and cellulose materials. The resulting membrane sheets, under laboratory conditions, were used to evaluate the removal of surrogate radioactive materials for cesium-137 and strontium-90 from high caustic nuclear waste simulants. These membrane supports met the nominal requirement for nonchemical interaction with the embedded ion exchange materials and were porous enough to allow sufficient liquid flow. Some of this 47-mm size stamped out prototype titanium impregnated ion exchange membrane discs was found to remove more than 96% of dissolved cesium-133 and strontium-88 from a caustic nuclear waste ...

Energy Technology Data Exchange (ETDEWEB)

High-temperature LiCl-KCl molten salt medium provides an efficient way to produce the paramagnetic Eu(II) ion to be magnetically diluted into a diamagnetic host medium. Eu(II) was formed by a dissolution and an auto-reduction processes in a high-temperature LiCl-KCl eutectic melt at 723 K by using Eu{sub 2}O{sub 3} as a starting material. By using EPR and luminescence spectroscopic method, we studied the nature of the magnetically isolated paramagnetic Eu(II) ion diluted in a LiCl-KCl medium. With the aid of these spectroscopic tools, it was found that stable Eu(II) species was formed spontaneously at 723 K under anaerobic conditions. EPR and luminescence spectroscopy provided detailed information regarding the nature of the europium ion in a molten salt.

British Library Electronic Table of Contents (United Kingdom)

High-temperature LiCl-KCl molten salt medium provides an efficient way to produce the paramagnetic Eu(II) ion to be magnetically diluted into a diamagnetic host medium. Eu(II) was formed by a dissolution and an auto-reduction processes in a high-temperature LiCl-KCl eutectic melt at 723K by using Eu2O3 as a starting material. By using EPR and luminescence spectroscopic method, we studied the nature of the magnetically isolated paramagnetic Eu(II) ion diluted in a LiCl-KCl medium. With the aid of these spectroscopic tools, it was found that stable Eu(II) species was formed spontaneously at 723K under anaerobic conditions. EPR and luminescence spectroscopy provided detailed information regarding the nature of the europium ion in a molten salt.

British Library Electronic Table of Contents (United Kingdom)

In this study we compared various maturity dependent aromatic, steroid and triterpenoid hydrocarbon ratios in bitumens that are freely extractable from sedimentary rocks (Bitumen I) with those in second extracts that comprised hydrocarbons closely associated with the kerogen/mineral matrix (Bitumen II). Bitumen II was released through kerogen isolation and demineralisation using HCl and HF/H3BO3. The samples studied, although of similar age, come from different localities. They represent a range of facies and two kerogen types (II and III), and all were deposited under marine conditions. The results show that the more stable b isomers of methylnaphthalene (MN) and methylphenanthrene (MP) are relatively more abundant in Bitumen II. The difference between the methylnaphthalene ratio (MNR) of...

British Library Electronic Table of Contents (United Kingdom)

Even the presence of very low concentrations of dyes (1mgL-1) in the effluent is highly visible and is considered aesthetically undesirable. It must be removed from wastewater completely. This study systematically evaluates the performance of adsorption (three kinds of powdered activated carbons), coagulation (AlCl36H2O) and membrane (submerged hollow fiber microfiltration) processes individually in treating two kinds of reactive dyes (Orange 16 and Black 5) and then using a hybrid process with combined coagulation-adsorption-membrane treatment system. Adsorption capacity and kinetics of Orange 16 were much higher and faster than those of Black 5. The dye removal efficiency by coagulation was highly dependent on dye concentration and solution pH. The hybrid process performance was far more...