idiopathic scoliosis undergoing: Topics by WorldWideScience.org

Undiagnosed osteoid osteoma of the spine presenting as painful scoliosis from adolescence to adulthood: a case report

Objectives: To report six month outcome in patients undergoing their first pulmonary vein ablation procedure for idiopathic atrial fibrillation (AF) at a “non-pioneering”...Full Text Available

2005-01-01

2

Optical Coherence Tomography Findings in Idiopathic Macular Holes

Presented here is a case of a young woman, with an undiagnosed osteoid osteoma of the spine, which presented with painful scoliosis in adolescence and was treated by bracing until her accession to adulthood....Full Text Available

3

Nonchylous idiopathic pleural effusion in the newborn

Purpose. To describe the characteristics of idiopathic macular holes (MH) on optical coherence tomography (OCT) and correlate OCT with clinical assessment. Design....Full Text Available

2011-01-01

4

Idiopathic (primary) achalasia

Congenital isolated pleural effusion is a rare cause of respiratory distress in neonates. It is usually chylous. Herein, we report a rare case of nonchylous congenital idiopathic pleural effusion.

2011-01-01

5

Ultrasonography and color Doppler of proximal gluteal enthesitis in juvenile idiopathic arthritis: a descriptive study

Idiopathic achalasia is a primary esophageal motor disorder characterized by esophageal aperistalsis and abnormal lower esophageal sphincter (LES) relaxation in response to deglutition. It is a rare...Full Text Available

6

The use of etoricoxib to treat an idiopathic stabbing headache: a case report

BackgroundThe presence of enthesitis (insertional inflammation) in patients with juvenile idiopathic arthritis (JIA) is difficult to establish clinically and may influence classification...Full Text Available

7

Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis

According to the International Headache Society, idiopathic stabbing headache (ISH), an indomethacin-responsive headache syndrome, is a paroxysmal disorder of short duration manifested as head pain...Full Text Available

8

Idiopathic venous thromboembolism and thrombophilia

IntroductionPrevious observations suggest that active systemic juvenile idiopathic arthritis (sJIA) is associated with a prominent erythropoiesis gene-expression signature. The aim...Full Text Available

2010-01-01

9

Combined photodynamic therapy and intravitreal bevacizumab for idiopathic polypoidal choroidal vasculopathy: one-year follow-up

During the past decade idiopathic venous thromboembolism has become a separate entity, a chronic illness which has required prolonged anticoagulation and other prevention strategies to avoid recurrences....Full Text Available

2011-02-15

10

Abnormalities of GATA-1 in Megakaryocytes from Patients with Idiopathic Myelofibrosis

ObjectiveTo report the efficacy and safety of combined photodynamic therapy (PDT) and intravitreal bevacizumab (IVB) injection in the treatment of idiopathic polypoidal choroidal...Full Text Available

2010-01-01

11

Positional Stretching of the Coracohumeral Ligament on a Patient with Adhesive Capsulitis: A Case Report

The abnormal megakaryocytopoiesis associated with idiopathic myelofibrosis (IM) plays a role in its pathogenesis. Because mice with defective expression of transcription factor GATA-1 (GATA-1^low...Full Text Available

2005-09-01

12

Paradoxical function for the receptor for advanced glycation end products in mouse models of pulmonary fibrosis

Idiopathic frozen shoulder is a common medical diagnosis for patients seeking physical therapy. Radiographic and surgical evidence exists that describes the coracohumeral ligament (CHL) as a major contributor...Full Text Available

2009-01-01

13

Increased wind-up to heat pain in women with a childhood history of functional abdominal pain

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor survival. The identification of therapeutic targets is essential to improving outcomes. Previous studies found that expression...Full Text Available

2011-03-31

14

Disability and Psychologic Distress in Patients with Nonspecific and Specific Arm Pain

Idiopathic or functional abdominal pain (FAP) is common in school-age children and typically reflects a functional gastrointestinal disorder (FGID). FGIDs in adults have been distinguished by...Full Text Available

2011-04-01

15

What is the heritable component of spinal deformities in the European sea bass (Dicentrarchus labrax)?

Psychological illness influences the experience and expression of pain and disability. We tested three null hypotheses: (1) patients with nonspecific pain (medically unexplained and idiopathic) and...Full Text Available

2008-11-01

16

British Library Electronic Table of Contents (United Kingdom)

Malformations in farmed fish are a prime research topic as it has a major impact on fish welfare and on the economical value of the product. In this study, the genetic component of spine deformities was estimated in European sea bass, a major species of Mediterranean aquaculture, with the use of a posteriori reconstruction of pedigree with microsatellites. Our population exhibited a very high malformation rate (81%), probably due to intense swimming of fish during pre-growing. The heritability of global spine deformities was evaluated to be 0.21?0.04 on the underlying scale (0.33?0.06 for lordosis, 0.13?0.04 for scoliosis). Deformities scored by an internal or external examination turned out to be genetically the same trait (genetic correlations>0.9), although phenotypic correlations were ...

2009-01-01

17

Pirfenidone in idiopathic pulmonary fibrosis: the CAPACITY program

British Library Electronic Table of Contents (United Kingdom)

Idiopathic pulmonary fibrosis is the most lethal form of diffuse lung fibrosis, killing approximately half of those affected within 2-3 years of diagnosis. Until recently, no therapies had been shown to have an impact on disease progression. The Clinical Studies Assessing Pirfenidone (Esbriet) in IPF: Research of Efficacy and Safety Outcomes (CAPACITY) program comprised two almost identical double-blind placebo-controlled studies assessing the effects of pirfenidone on change in forced vital capacity, the primary end point, over a 72-week period. One of these studies was positive, matching in magnitude the benefit seen in two previous positive Japanese studies. The other study did not meet its primary end point but positive trends were consistent in this and a number of secondary end point...

2011-01-01

18

Preoperative factors predictive of postoperative decimal visual acuity ? 1.0 following surgical treatment for idiopathic epiretinal membrane

An evaluation of the utility of routine laboratory monitoring of juvenile idiopathic arthritis (JIA) patients using non-steroidal anti-inflammatory drugs (NSAIDs): a retrospective review

Purpose:To report the preoperative best-corrected visual acuity (BCVA) and foveal thickness (FT) values that lead to a postoperative decimal BCVA of ≥1.0 after surgical removal...Full Text Available

2011-01-01

19

Use of sodium chromate Cr/sub 51/ in diagnosing childhood idiopathic pulmonary hemosiderosis

BackgroundNo consensus evidence-based guidelines for the routine laboratory monitoring of children with JIA receiving non-steroidal anti-inflammatory drugs (NSAIDs) exist. The purpose...Full Text Available

20

Idiopathic renal hematuria in a military working dog.

The diagnosis of idiopathic pulmonary hemosiderosis (IPH) may be elusive. A 6-year-old boy had microcytic hypochromic anemia and a hemolytic component. Hemosiderin-laden macrophages were not found in the gastric aspirate. He had no pulmonary signs or symptoms. Extensive hematologic and roentgenologic investigations failed to reveal the cause of the anemia. Quantitative serial scintigraphic scanning showed significant (35%) pulmonary sequestration of autologous erythrocytes labeled with sodium chromate Cr51. The half-life of the RBCs was moderately decreased (half-life, 15 days; normal, 25 to 35 days). An open-lung biopsy spece Cr51. The half-life of the RBCs was moderately decreased (half-life, 15 days; normal, 25 to 35 days). An open-lung biopsy specimen confirmed the diagnosis of IPH. A diagnosis of IPH should be considered when children have iron deficiency anemia and pulmonary signs or symptoms. Organ sequestration studies may be helpful in equivocal cases.

1984-08-01

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The Effect of Live Classical Piano Music on the Vital Signs of Patients Undergoing Ophthalmic Surgery

A 1.5-year-old male Belgian Malinosis Military Working Dog presented with a 1-month history of intermittent hematuria. Diagnostic ultrasound and contrast radiography demonstrated large blood clots in the urinary bladder and a filling defect in the right renal pelvis. At surgery, clotted blood was present in the right ureter and bladder. Following right nephrectomy, the dog returned to training. One month later, elevations in urea nitrogen and creatinine were noted. Hematuria recurred at 3 months and the dog was found dead in its kennel. Necropsy showed a blood-filled left renal pelvis and ureter. PMID:1454185

1992-10-01

22

Comparison of prasugrel and clopidogrel in patients with acute coronary syndrome undergoing percutaneous coronary intervention

ContextMusic and surgery.ObjectiveTo determine the effect of live classical piano music on vital signs of patients undergoing ophthalmic surgery.DesignRetrospective...Full Text Available

23

The effect of magnesium sulfate on postoperative pain in patients undergoing major abdominal surgery under remifentanil-based anesthesia

Antiplatelet agents are the cornerstone of treatment for patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). Clopidogrel, when added to aspirin, has demonstrated...Full Text Available

2009-01-01

24

KoreaScience (Korea)

Full Text Available

2008-09-01

25

[Pulmonary vascular manifestations in hereditary hemorrhagic telangiectasia].

Treatment of asymptomatic internal resorption of a maxillary premolar tooth in a military working dog.

Hereditary hemorrhagic telangiectasia (Osler-Rendu-Weber disease) is a genetic disorder with autosomal dominance, variable penetrance, and an estimated prevalence of 1/10,000 inhabitants in France. Diagnosis is based on clinical criteria including epistaxis, telangiectasia, visceral manifestations, and familial occurrence. Pulmonary arteriovenous malformations, present in 15-33% of patients, are its primary visceral complications. The disease may be revealed by infectious and ischemic neurological manifestations due to paradoxical embolism. The high frequency of neurologic complications even in asymptomatic patients justifies systematic screening for pulmonary arteriovenous malformations. Treatment of these malformations is based on percutaneous transcatheter coil embolization of the feeding artery. Pulmonary arterial hypertension is rare in this disease. It may be due to systemic arteriovenous shunting in the liver, which increases cardiac output, or be similar to ...

2005-11-01

26

The use of peritoneal venous shunting for intractable neonatal ascites: a short case series

An asymptomatic pink discoloration of a maxillary right fourth premolar tooth was discovered during a routine oral examination on a 9 year-old Belgian Malinois dog. A radiolucent lesion was seen in the pulpal chamber on radiographic examination. The lesion had perforated the mesiobuccal root of the tooth. The primary differential diagnosis was idiopathic internal resorption. The tooth was treated by partial resection (removal of the mesiobuccal root and associated crown). A vital pulpotomy and amalgam restoration was performed on the remaining tooth structure. A follow-up 1 year later demonstrated a successful treatment outcome. The animal was asymptomatic and able to perform military duties. Clinical and radiographic signs of healing were evident and the tooth was functional. PMID:10518874

1998-12-01

27

British Library Electronic Table of Contents (United Kingdom)

Introduction: Intractable ascites in neonates has a varied etiology; and often, the cause is idiopathic. The management usually consists of observation, diuretics, paracentesis, albumin replacements, and self correction. However, in some cases, the above treatment remains unsuccessful. Results: We present 2 cases of intractable ascites causing metabolic abnormalities, severe protein and immunoglobulin loss, and respiratory compromise. Although the use of peritoneovenous shunts for intractable ascites has been reported previously, our cases differ in both technique and patient size. Our first patient is an ex-28-week premature, 1.4-kg infant with intractable ascites for which a peritoneal drain was initially placed. After 3 weeks and putting out nearly 300 mL of ascitic fluid daily, we plac...

2011-01-01

28

Mucosal Inflammation in Spondylarthritides: Past, Present, and Future

British Library Electronic Table of Contents (United Kingdom)

Spondylarthritides (SpA) and inflammatory bowel disease (IBD) are idiopathic, chronic inflammatory disorders. Although they are very distinct and well-defined entities, there is clinical and genetic evidence supporting some degree of overlap between the pathogenesis of the two. Subclinical gut inflammation is present in up to two thirds of all SpA patients and can evolve into IBD. This subclinical gut inflammation has been shown to be strongly associated with joint inflammation, providing a clue for a common pathophysiologic background. Despite extensive research progress in the field over the past few years, many questions remain unanswered. In this paper, we focus on the clinical, genetic, and pathophysiologic overlap of SpA and IBD. Furthermore, we discuss some of the targets that may i...

2011-01-01

29

Manganese Induces IGF-1 and Cyclooxygenase-2 Gene Expressions in the Basal Hypothalamus during Prepubertal Female Development

British Library Electronic Table of Contents (United Kingdom)

Precocious puberty is a significant child health problem, especially in girls, because 95% of cases are idiopathic. Our earlier studies demonstrated that low-dose levels of manganese (Mn) caused precocious puberty via stimulating the secretion of luteinizing hormone-releasing hormone (LHRH). Because glial-neuronal communications are important for the activation of LHRH secretion at puberty, we investigated the effects of prepubertal Mn exposure on specific glial-derived puberty-related genes known to affect neuronal LHRH release. Animals were supplemented with MnCl2 (10 mg/kg) or saline by gastric gavage from day 12 until day 22 or day 29, then decapitated, and brains removed. The site of LHRH release is the medial basal hypothalamus (MBH), and tissues from this area were analyzed by real-...

2011-01-01

30

Prognostic implications of pulmonary hypertension in patients with severe aortic stenosis

British Library Electronic Table of Contents (United Kingdom)

ObjectiveWe sought to determine the clinical outcomes of patients undergoing surgical aortic valve replacement with hemodynamically confirmed severe pulmonary hypertension and aortic stenosis and compare them with the outcomes of patients not undergoing aortic valve replacement and patients undergoing aortic valve replacement with mild-to-moderate pulmonary hypertension. MethodsA total of 317 patients with severe aortic stenosis (aortic valve area 35 mm Hg) was present in 81 patients, of whom 35 (43.2%) underwent surgical aortic valve replacement. We compared the clinical outcomes of these 35 patients with the 46 patient...

2011-01-01

31

The mammalian oocyte orchestrates the rate of ovarian follicular development

State II Dissociation Element Formation Following Activator Excision in Maize

The development of both the mammalian oocyte and the somatic cell compartments of the ovarian follicle is highly coordinated; this coordination ensures that the ovulated oocyte is ready to undergo fertilization...Full Text Available

2002-03-05

32

Prognostic Factors for Failure after Prostatectomy

Active Activator (Ac) elements undergo mutations to become nonautonomous Dissociation (Ds) elements at a low frequency. To understand...Full Text Available

2007-10-01

33

IDSS: deformation invariant signatures for molecular shape comparison

Several randomized studies have been completed in prostate cancer that show a benefit to immediate postoperative treatment in patients undergoing prostatectomy. In one of the studies, there was even...Full Text Available

34

Fatigue Is a Predictor for Cardiovascular Outcomes in Patients Undergoing Hemodialysis

BackgroundMany molecules of interest are flexible and undergo significant shape deformation as part of their function, but most existing methods of molecular shape comparison (MSC)...Full Text Available

35

Calculation of model neutron stars with pion condensation

Background and objectives: Despite potential significance of fatigue and its underlying components in the occurrence of cardiovascular diseases, epidemiologic data showing the link are virtually limited....Full Text Available

2010-04-01

36

Bone geometry, biomechanics, and mineral content of the distal radius in uremic patients with severe hyperparathyroidism

It is shown numerically that on a time scale of order 1 msec a neutron star with pion condensation will undergo separation into a core and an envelope with a sharp interface. The envelope will not, however, be ejected.

1982-01-01

37

Anxiety and Cancer Treatment: Response to Stressful Radiotherapy

Bone integrity and mineral status were studied with a noninvasive method in uremic patients with severe secondary hyperparathyroidism undergoing maintenance hemodialysis.

1999-04-01

38

Aging in Language Dynamics

Previous research with individuals undergoing surgery or diagnostic procedures provided a conceptual framework for analysis of radiation therapy, a common form of cancer treatment. The present...Full Text Available

1984-01-01

39

A Review of Psychosocial Outcomes for Patients Seeking Cosmetic Surgery

Human languages evolve continuously, and a puzzling problem is how to reconcile the apparent robustness of most of the deep linguistic structures we use with the evidence that they undergo possibly...Full Text Available

40

Assessment of chromosomal abnormalities in sperm of infertile men using sperm karyotyping and multicolour fluorescence in situ hybridization (FISH)

The authors reviewed the literature on psychological and psychosocial outcomes for individuals undergoing cosmetic surgery, to address whether elective cosmetic procedures improve psychological...Full Text Available

2004-04-01

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41

One-year follow-up of the effects of sildenafil on pulmonary arterial hypertension and veno-occlusive disease

Individuals with male factor infertility resulting from idiopathic oligo-, astheno- or teratozoospermia are frequently offered IVF in an attempt to increase their chances of having a child. A concern remains whether these infertile males have an elevated risk of transmitting chromosomal abnormalities to their offspring. Sperm chromosomal complements from these men were assayed using the human sperm/hamster oocyte fusion system and fluorescence in situ hybridization (FISH) on sperm nuclei. For each of 5 infertile patients, 100 sperm karyotypes were analyzed and multicolour FISH analysis was performed on a minimum of 10,000 sperm nuclei for each chromosome-specific DNA probe for chromosomes 1 (pUC1.77), 12 (D12Z3), X (XC) and Y (DYZ3). As a group, the infertile patients showed increased frequencies of both numerical ({chi}{sup 2}=17.26, {proportional_to} <0.001) and total abnormalities ({chi}{sup 2}=7.78, {proportional_to} <0.01) relative to control donors when ...

1994-09-01

42

Scientific Electronic Library Online (English)

Abstract in english We hypothesized that chronic oral administration of the phosphodiesterase-5 inhibitor sildenafil could improve the exercise capacity and pulmonary hemodynamics in patients with pulmonary arterial hypertension (PAH) on the basis of previous short-term studies. We tested this hypothesis in 14 subjects with PAH, including seven patients with the idiopathic form and seven patients with atrial septal defects, but no other congenital heart abnormalities. Patients were subjected (more) to a 6-min walk test and dyspnea was graded according to the Borg scale. Pulmonary flow and pressures were measured by Doppler echocardiography. Patients were given sildenafil, 75 mg orally three times a day, and followed up for 1 year. Sildenafil therapy resulted in the following changes: increase in the 6-min walk distance from a median value of 387 m (range 0 to 484 m) to 462 m (range 408 to 588 m; P

2005-02-01

43

Citrat og nyresten

DEFF Research Database (Denmark)

Citrate is an important naturally occurring inhibitor of calcium stone formation in urine. Urinary citrate excretion was examined in 43 consecutive patients with recurrent idiopathic calcium nephrolithiasis and in 50 normal controls by a specific enzymatic technique. Hypocitraturia (<1.6 mmol/24h) was found in 14 (33%) stone formers compared to 6 (12%) normal controls (p = 0.03). Citrate excretion expressed as citrate-creatinine ratio in 24 hour urine samples was significantly lower in the stone formers than in the healthy controls (p = 0.03), and significantly lower in healthy men, compared to healthy females (p = 0.006). There was a great variability in urinary citrate levels in both groups, and a considerable overlap in the urinary citrate excretion between normal subjects and stone formers. Factors other than urinary citrate excretion must therefore be of importance in the pathophysiology of calcium stone formation. Citrate-calcium ratio in urine proved to ...

1993-01-01

44

Zoledronate to Preserve Bone Mineral Density

Validity of Cardiac Markers as Diagnostic and Prognostic Indicators of Complications in Patients undergoing Percutaneous Coronary Intervention

Phase II Randomized Study of the Effect of Zoledronate Versus Observation on Bone Mineral Density of the Lumbar Spine in Patients Undergoing Risk-Reducing Excision of Both Ovaries (GOG-0215). See the protocol summary.

45

Use of clopidogrel in the reduction of myocardial damage during percutaneous coronary intervention

ObjectivesThe aim of this study was to assess the diagnostic and prognostic value of heart-type fatty acid-binding protein (H-FABP) in elective percutaneous coronary intervention...Full Text Available

2010-04-01

46

Transplantation of allogeneic T cells alters iron homeostasis in NOD/SCID mice

It is estimated that approximately a quarter of patients undergoing coronary intervention may have significant post-procedural creatinine (CK)/creatinine kinase myocardial band (CK-MB) elevations and...Full Text Available

2009-01-01

47

Transcriptional coactivator PGC-1? promotes peroxisomal remodeling and biogenesis

Iron overload is common in patients undergoing allogeneic hematopoietic cell transplantation (HCT), but the mechanisms leading to overload are unknown. Here, we determined iron levels and the expression...Full Text Available

2009-02-19

48

Sex and Death: The Effects of Innate Immune Factors on the Sexual Reproduction of Malaria Parasites

Mitochondria and peroxisomes execute some analogous, nonredundant functions including fatty acid oxidation and detoxification of reactive oxygen species, and, in response to select metabolic cues, undergo...Full Text Available

2010-11-23

49

Reduced thermal sensitivity and Nav1.8 and TRPV1 channel expression in sensory neurons of aged mice

Malaria parasites must undergo a round of sexual reproduction in the blood meal of a mosquito vector to be transmitted between hosts. Developing a transmission-blocking intervention to prevent parasites...Full Text Available

2011-03-01

50

Rapid Modulation of Spinach Leaf Nitrate Reductase by Photosynthesis ¹

Sensory neurons in aging mammals undergo changes in anatomy, physiology and gene expression that correlate with reduced sensory perception. In this study we compared young and aged mice to identify...Full Text Available

2006-06-01

51

Quality-of-Life and Surgical Treatments for Rectal Cancer-a Longitudinal Analysis Using the California Cancer Registry

Assimilatory nitrate reductase activity (NRA) in crude spinach leaf (Spinacia oleracea) extracts undergoes rapid changes following fluctuations in photosynthesis brought about by changes...Full Text Available

1991-06-01

52

QOI10/477: The medCERTAIN Project: Rating and certification of Internet health information using medPICS

BackgroundHeterogeneous results for research investigating health-related quality of life (HRQL) in patients undergoing sphincter-ablating procedures for rectal cancer...Full Text Available

2010-08-01

53

Prostaglandin-induced Abortion: Assessment of Operative Complications and Early Morbidity

IntroductionHealth information on the Internet undergoes no quality control at the stage of production, thus its quality is highly variable, making it difficult...Full Text Available

54

Programmed cell death in castor bean endosperm is associated with the accumulation and release of a cysteine endopeptidase from ricinosomes

A total of 626 patients undergoing a prostaglandin-induced abortion, the majority in the second trimester, have been analysed for complications occurring during inpatient treatment. Of the last 155...Full Text Available

1974-12-21

55

Prevalence of Renal Artery and Kidney Abnormalities by Computed Tomography among Healthy Adults

The cells of the endosperm of castor bean seeds (Ricinus communis) undergo programmed cell death during germination, after their oil and protein reserves have been mobilized. Nuclear...Full Text Available

1999-11-23

56

Predictions for the outcome of rodent carcinogenicity bioassays: identification of trans-species carcinogens and noncarcinogens.

Background and objectives: Management of incidental renal artery and kidney abnormalities in patients undergoing computed tomography scans is a clinical challenge because their frequency in healthy...Full Text Available

2010-03-01

57

Post-operative telephone review is cost-effective and acceptable to patients

Thirty chemicals or substances currently undergoing long-term carcinogenicity bioassays in rodents have been used in a project to further evaluate methods and information that may have the capability...Full Text Available

1996-10-01

58

Physiologic Responses to Infrarenal Aortic Cross-Clamping during Laparoscopic or Conventional Vascular Surgery in Experimental Animal Model: Comparative Study

IntroductionPatients undergoing selective minor emergency and elective procedures are followed up by a nurse-led structured telephone review six weeks post-operatively in our hospital....Full Text Available

2010-05-01

59

P2Y₂ Nucleotide Receptor-Mediated Responses in Brain Cells

The aim of this study was to compare the hemodynamic and ventilatory effects of prolonged infrarenal aortic cross-clamping in pigs undergoing either laparotomy or laparoscopy. 18 pigs were used for...Full Text Available

2008-01-01

60

Outcome of early surgery after coronary angioplasty.

Acute inflammation is important for tissue repair; however, chronic inflammation contributes to neurodegeneration in Alzheimer’s disease (AD) and occurs when glial cells undergo prolonged...Full Text Available

2010-06-01

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61

On the spontaneous stochastic dynamics of a single gene: complexity of the molecular interplay at the promoter

Nineteen of 69 patients undergoing coronary angioplasty required immediate coronary surgery after the procedure. Six of these operations were planned as a result of angioplasty that failed without producing...Full Text Available

1986-03-01

62

Multiple-dose pharmacokinetics of amikacin and ceftazidime in critically ill patients with septic multiple-organ failure during intermittent hemofiltration.

BackgroundGene promoters can be in various epigenetic states and undergo interactions with many molecules in a highly transient, probabilistic and combinatorial way, resulting in...Full Text Available

63

Micturition in conscious rats with and without bladder outlet obstruction: role of spinal alpha 1-adrenoceptors.

The pharmacokinetic parameters of amikacin and ceftazidime were assessed in four patients undergoing hemofiltration for septic shock. The parameters were assessed during hemofiltration and in the interim...Full Text Available

1993-03-01

64

Medico-legal autopsy in postoperative hemodynamic collapse following coronary artery bypass surgery

1. In normal rats and rats with bladder hypertrophy secondary to outflow obstruction, undergoing continuous cytometry, we examined the responses to the selective alpha 1-adrenoceptor antagonist doxazosin...Full Text Available

1996-03-01

65

Markets and commercialization scenarios for emerging fuel cells in evolving electricity markets

Sudden unexpected postoperative hemodynamic collapse with a high mortality develops in 1–3% of patients undergoing coronary artery bypass surgery (CABG). The contribution of surgical graft complications...Full Text Available

2011-03-01

66

Management of nucleus loss into the vitreous: long term follow up in 63 patients

Electricity markets in the United States are undergoing unprecedented structural changes as a result of the confluence of regulatory, competitive, and technological forces. This paper introduces these structural changes and forces and discuss the implications, markets and commercialization scenarios for emerging fuel cells in evolving US electricity markets.

1996-12-31

67

Legionella tucsonensis sp. nov. isolated from a renal transplant recipient.

Background:The aim of present study is to determine the long-term results of patients who undergo pars plana vitrectomy after retained nucleus into the vitreous.Setting:Service...Full Text Available

2007-12-01

68

Iron Overload, Hematopoietic Cell Transplantation, and Graft-versus-Host Disease

A Legionella-like organism (strain 1087-AZ-H) was isolated from a pleural-fluid specimen from a renal transplant patient undergoing immunosuppressive therapy. Growth characteristics and gas-liquid chromatography...Full Text Available

1989-08-01

69

Intraoperative angioembolization in the management of pelvic-fracture related hemodynamic instability

Many patients who undergo hematopoietic cell transplantation (HCT) present with anemia and have received red blood cell transfusions before HCT. As a result, iron overload is frequent and appears...Full Text Available

2009-10-01

70

Impact of intraoperative lung-protective interventions in patients undergoing lung cancer surgery

BackgroundThis case series report discusses patients presenting with hemorrhage and hemodymanic compromise due to severe pelvic fractures and undergoing intraoperative angioembolization...Full Text Available

71

Heterogeneity of engrafted bone-lining cells after systemic and local transplantation

IntroductionIn lung cancer surgery, large tidal volume and elevated inspiratory pressure are known risk factors of acute lung (ALI). Mechanical ventilation with low tidal volume...Full Text Available

2009-01-01

72

Free radical mediated cell toxicity by redox cycling chemicals.

The outcome of various osteoprogenitor-cell transplantation protocols was assessed using Col1a1-GFP reporter transgenic mice. The model requires the recipient mice to undergo lethal total body irradiation...Full Text Available

2005-11-15

73

Expert Knowledge in a Joint Task Force Headquarters.

Free radical formation has been implicated in the toxicity of a wide range of xenobiotics. In recent years, particular interest has been paid to compounds which can undergo a one electron reduction...Full Text Available

1987-06-01

74

Experimental autoimmune encephalomyelitis mobilizes neural progenitors from the subventricular zone to undergo oligodendrogenesis in adult mice

Officers receive service-specific education and undergo experiences within their components that provide the expert knowledge that enables them to operate in their respective military departments. Given the Department of Defense (DoD) emphasis on service ...

2005-01-01

75

Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials

The destiny of the mitotically active cells of the subventricular zone (SVZ) in adult rodents is to migrate to the olfactory bulb, where they contribute to the replacement of granular and periglomerular...Full Text Available

2002-10-01

76

Development and Validation of the Convalescence And Recovery Evaluation (CARE) for Measuring Quality of Life after Surgery

SummaryBackgroundPatients undergoing dialysis have a substantially increased risk of cardiovascular mortality and morbidity. Although several trials have shown the...Full Text Available

2009-03-21

77

Correlates and Outcomes of Fatigue among Incident Dialysis Patients

PurposeTo develop a generic instrument for measuring short-term health status in the recovery period among patients undergoing abdominal and pelvic surgery.Full Text Available

2008-08-01

78

Coping with Test Pain, Discomfort, and Anxiety

Background & objectives: Fatigue is a debilitating symptom experienced by patients undergoing dialysis, but there is only limited information on its prevalence and its association with patient...Full Text Available

2009-11-01

79

Chest pain and angiographically normal coronary arteries. Implications for treatment.

... Search Help? Coping with Test Pain, Discomfort, and Anxiety Introduction | Be Prepared | Know Your Tests | Relax | Conclusion ... though they may feel some embarrassment, discomfort, or anxiety at the outset. If undergoing medical tests makes ...

80

Characterization of ?-Butyrolactone Autoregulatory Signaling Gene Homologs in the Angucyclinone Polyketide WS5995B Producer Streptomyces acidiscabies?

Approximately 20% to 30% of patients who undergo coronary arteriography for the evaluation of chest pain are found to have normal coronary arteries. These patients have a survival rate comparable to...Full Text Available

1993-01-01

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81

Changes in Skeletal Mineral in Patients on Prolonged Maintenance Dialysis

Organisms belonging to the genus Streptomyces produce numerous important secondary metabolites and undergo a sophisticated morphological differentiation program. In many instances these...Full Text Available

2009-08-01

82

Challenges of functional imaging research of pain in children

The measurement of bone loss in patients undergoing maintenance dialysis over a period of two and a half years is reported. The tendency to lose bone is a likely event in renal failure, but depends...Full Text Available

1973-12-01

83

Catalyzing Social Support for Breast Cancer Patients

Functional imaging has revolutionized the neurosciences. In the pain field it has dramatically altered our understanding of how the brain undergoes significant functional, anatomical and chemical changes...Full Text Available

84

Calcification of subcutaneously implanted type I collagen sponges. Effects of formaldehyde and glutaraldehyde pretreatments.

Social support is a critical, yet underutilized resource when undergoing cancer care. Underutilization occurs in two conditions: (a) when patients fail to seek out information, material assistance,...Full Text Available

2010-01-01

85

Bladder function after abdominoperineal resection of the rectum for anorectal cancer. Urodynamic investigation before and after operative in a consecutive series.

Although collagen-containing implants are widely used in various surgical applications, there has been relatively little attention paid to the possibility that this type of biomaterial may undergo pathologic...Full Text Available

1986-01-01

86

Aspirin and Clopidogrel Response Variability

In a consecutive series of 26 patients (10 men and 16 women) undergoing abdominoperineal resection of the rectum, cystometry and pressure-flow-EMG measurements were made preoperatively and three and...Full Text Available

1980-01-01

87

Appearance of beta-endorphin-like immunoreactivity in human ventricular cerebrospinal fluid upon analgesic electrical stimulation.

Antiplatelet resistance has been proposed as a possible mechanism to explain recurrent cardiovascular events in patients who have coronary artery disease and who are undergoing dual antiplatelet therapy....Full Text Available

2008-01-01

88

An evaluation of cerebrospinal fluid oligoclonal banding confirmed by immunofixation on agarose gel.

beta-Endorphin-like immunoreactivity in human ventricular cerebrospinal fluid was measured with a specific radioimmunoassay. The subjects were undergoing a surgical procedure for relief of chronic intractable...Full Text Available

1978-10-01

89

Alien mink predation induces prolonged declines in archipelago amphibians

The cerebrospinal fluid (CSF) from 115 consecutive patients undergoing diagnostic lumbar puncture or myelography was examined to determine the usefulness of immunofixation, following agarose gel electrophoresis,...Full Text Available

1983-06-01

90

ALTERATION OF THE PKC-MEDIATED SIGNALING PATHWAY FOR SMOOTH MUSCLE CONTRACTION IN OBSTRUCTION-INDUCED HYPERTROPHY OF THE URINARY BLADDER

Amphibians are undergoing enigmatic global declines variously attributed to a complex web of anthropogenic forces. Alien predators pose a fundamental threat to biodiversity generally that is predicted...Full Text Available

2006-05-22

91

Biopsy examination during the course of radiotherapy. Progress report. [DNA content of tumor cells in biopsy samples determined by microfluorometric or multiangle light-scatter spectrometry

Normal urinary bladder function requires contraction and relaxation of the detrusor smooth muscle (DSM). The DSM undergoes compensatory hypertrophy in response to partial bladder outlet obstruction...Full Text Available

2009-07-01

92

Prevalence and incidence of depressive and anxious symptoms in couples undergoing assisted reproductive treatment in an Italian infertility department

Studies begun during the first year of this project on biopsies from spontaneous tumors in dogs and from human patients undergoing radiotherapy treatment were continued. The results indicate that significant fractions of the spontaneous tumors in dogs and cervical carcinomas in patients undergoing radiotherapy have a DNA content higher than normal diploid cells. The higher DNA content in tumor cells permits distinguishing them from normal cells in the biopsy material with the aid of flow microfluorometric (FMF) instrumentation or multiangle light-scatter spectrometry.

1977-12-01

93

British Library Electronic Table of Contents (United Kingdom)

Objective: We have conducted a longitudinal observational study in order to evaluate the prevalence and the incidence of depressive and anxious symptoms in women and men seeking infertility treatment and to analyze associated factors or risk factors for these kinds of disorders. Study design: A total of 1000 consecutive couples that visited our center for the first time were asked to join this study. Depressive and anxious symptoms were assessed with self-rating Zung Depression Scale (ZDS) and Zung Anxiety Scale (ZAS) questionnaires. A second assessment was planned at the time of b HCG dosage (or at the moment of cycle suspension). A standard questionnaire was used to investigate socio-demographic information and the psychological aspects of couples undergoing in vitro fertilization (IVF) ...

2011-01-01

94

Effects of Valproic Acid on Organic Acid Metabolism in Children: A Metabolic Profiling Study

British Library Electronic Table of Contents (United Kingdom)

Young children are at increased risk for valproic acid (VPA) hepatotoxicity. Urinary organic acid profiles, as a surrogate of mitochondrial function, were obtained in children 1.9 to 17.3 years of age (n = 52) who were undergoing treatment with VPA for seizure disorders. Age-matched patients receiving treatment with carbamazepine (CBZ; n = 50) and healthy children not undergoing treatment (n = 22) served as controls. Age-related changes in organic acid profiles were observed in all three groups. Although the untreated and CBZ control groups were indistinguishable from each other with respect to the principal-component analysis (PCA) score plots of the subjects, a distinct boundary was apparent between the VPA and each of the control groups. Interindividual variability was observed in the V...

2011-01-01

95

Bilateral but not Unilateral Testicular Hypotrophy Predicts for Severe Impairment of Semen Quality in Men with Varicocele Undergoing Infertility Evaluation

British Library Electronic Table of Contents (United Kingdom)

ObjectivesVaricocele is a common cause of infertility, and varicocele-associated testicular hypotrophy has been described as a potential cause of decreased semen quality. We investigated the relationship between testicular hypotrophy and poor semen quality in infertile men with varicoceles. We hypothesized that bilateral hypotrophy is required before the semen quality is severely impaired.MethodsWe retrospectively identified consecutive patients with palpable varicoceles undergoing an infertility evaluation at a single academic center. Each patient was evaluated by the same clinician with history and physical examination. Testicular hypotrophy was defined as a size discrepancy of greater than 3 mL or an absolute size of less than 14 mL. Multivariate logistic regression analysis was used to...

2008-01-01

96

A Comparison of POSSUM and GPS Models in the Prediction of Post-operative Outcome in Patients Undergoing Oesophago-gastric Cancer Resection

British Library Electronic Table of Contents (United Kingdom)

Background There is some evidence that a patient?s pre-operative condition influences short-term and long-term post-operative outcomes. The aim of the present study is to compare the physiological and operative severity score for the enumeration of mortality and morbidity (POSSUM) and modified Glasgow prognostic score (mGPS) models in the prediction of post-operative outcome, both short term and long term, in patients undergoing resection of oesophago-gastric cancer. Patients and Methods Patients who underwent curative resection for oesophago-gastric cancer from January 2005 to May 2009 and who had data to score the POSSUM, P-POSSUM, O-POSSUM and mGPS models were included in the study. Observed morbidity and mortality rates were compared with predicted outcome in different risk groups. Bot...

2011-01-01

97

#left brace#311#right brace# Defects in ion-implanted silicon: The cause of transient diffusion, and a mechanism for dislocation formation

Pituitary disease in childhood: utility of magnetic resonance; Patologia hipofisaria en la edad pediatrica: unidad de la resonance magnetica

Ion implantation is used at several critical stages of Si integrated circuit manufacturing. The authors show how #left brace#311#right brace# defects arising after implantation are responsible for both enhanced dopant diffusion during annealing, and stable dislocations post-anneal. They observe #left brace#311#right brace# defects in the earliest stages of an anneal. They subsequently undergo rapid Ostwald ripening and evaporation. At low implant doses evaporation dominates, and they can quantitatively relate the interstitials emitted from these defects to the transient enhancement in diffusivity of dopants such as B and P. At higher doses Ostwald ripening is significant, and they observe the defects to undergo a series of unfaulting reactions to form both Frank loops and perfect dislocations. They demonstrate the ability to control both diffusion and dislocations by the addition of small amounts of carbon impurities.

1995-03-20

98

Disorders of brain development and phakomatosis

To assess the utility of magnetic resonance (MR) imaging in the study of pediatric patients with clinical suspicion of pituitary disease. We studied 18 patients aged 7 to 18 years.Fifteen had hormonal disturbances, two presented amenorrhea and 1 complained of headache, fever and symptoms of polyuria and polydipsia. All the patients were examined using a Siemens SP 42 1-Tesla MRI scanner. Sagittal and coronal T1-weighted spin-echo images were obtained; in addition T2-weighted spin-echo or fast spin-echo imaging was performed in ten cases and intravenous gadolinium was administered in nine. We found 9 patients with hypothalamic-pituitary dysgenesis, 2 with germinoma, 2 cases of pituitary hemosiderosis in patients with thalassemia, 2 cases of microadenoma, one abscess, one case of idiopathic central diabetes insipidus and one of Langerhans cell histiocytosis. MR enabled us to assess pituitary structural alterations in children with hypothalamic-pituitary hormone ...

2000-07-01

99

Assessment of bone formation and bone resorption in osteoporosis: a comparison between tetracycline-based iliac histomorphometry and whole body /sup 85/Sr kinetics

Full text: Disorders of brain development and phakomatosis are resulting from disturbed embryonic-foetal development One third of all major embryological anomalies involve CNS, and over 2000 different anomalies have been described. Anomalies of the brain often cause foetal and neonatal death, and mental and physical retardation in pediatric group. The majority of disorders of brain development and phakomatosis are idiopathic, and most of them are not hereditary or familial. Ultrasonography plays the important role in screening foetal and neonatal brain, but after closure of fontanels it is difficult to find the acoustic window. CT has limited contrast resolution, and disadvantage exposing infant to ionizing radiation. It is helpful to demonstrate the presence of calcifications. MR imaging has proved to be a diagnostic tool of major importance in children with disorders of brain development and phakomatosis. The excellent grey/white matter differentiation and ...

100

Use of platelet glycoprotein IIb/IIIa inhibitors in diabetics undergoing PCI for non-ST-segment elevation acute coronary syndromes: impact of clinical status and procedural characteristics

Bone formation and resorption have been measured in patients with idiopathic osteoporosis by histomorphometry of 7.5-mm trephine biopsies and in the whole body by 85Sr radiotracer methodology and calcium balances. The studies were synchronized and most were preceded by double in vivo tetracycline labeling. Correlations between histological and kinetic bone formation indices were better when better when based on the extent of double tetracycline labels than on measurements of osteoid by visible light microscopy. Correction of the kinetic data for long-term exchange, using 5 months' serial whole body counting of retained 85Sr, improved the fit of the kinetic to the histological data. A statistical analysis of the measurement uncertainties showed that the residual scatter in the best correlations (between exchange-corrected bone formation rates and double-labeled osteoid surface indices) could be attributed to measurement imprecision alone. The ...

1987-12-01

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101

Ternary aluminides LnPd[sub 2]Al with YPd[sub 2]Si-type structure

BackgroundThe most recent ESC guidelines for percutaneous coronary intervention (PCI) recommend the use of glycoprotein IIb/IIIa inhibitors (GPI) in high risk patients with non-ST-segment...Full Text Available

2010-06-01

102

Reversible conformational change in herpes simplex virus glycoprotein B with fusion-from-without activity is triggered by mildly acidic pH

Attempts to synthesize YPd[sub 2]Si-type representatives LnPd[sub 2]Al were successful only with Ln triple bond Ce, Pr, Nd. This orthorhombic structure (oP16; space group Pnma) is an ordered variant of the Fe[sub 3]C type. Only NdPd[sub 2]Al undergoes magnetic ordering above 2 K. (orig.)

1993-04-13

103

Radiological diagnosis of lesions of intervertebral discs

BackgroundThe pre-fusion form of the herpes simplex virus (HSV) fusion protein gB undergoes pH-triggered conformational change in vitro and during viral entry (Dollery...Full Text Available

104

Radiation doses and somatic risk to patients during cardiac radiological procedures

During their life, intervertebral discs undergo degenerative changes which need not necessarily become lesions. Conventional X-rays do not provide information on the condition of the intervertebral discs, so MRT or CT are recommended as primary techniques as they are non-invasive. Invasive methods like myelography and especially discography should not be used unless a case is highly problematic. In infants with pains in the back, MRT should be carried out as early as possible as there is nearly always an organic cause. (orig.)

2003-03-01

105

Point/counterpoint: dose-related issues in cardiac CT imaging

The radiation dose to a series of adult and paediatric patients undergoing cardiac catheterisations and adults having percutaneous transluminal coronary angioplasty has been measured/determined directly using lithium fluoride thermoluminescent dosemeters and indirectly using an air ionisation chamber which indicated exposure-area product. Somatic and genetic risks are estimated from the dosimetry results. It is suggested that the magnitude of the radiation hazard is negligible compared with other clinical hazards associated with these procedures. (author).

1986-01-01

106

British Library Electronic Table of Contents (United Kingdom)

This manuscript reviews some of the more controversial dose-related issues in cardiac CT imaging. Discussion covers the relative merits of cardiac CT versus MR, advantages and concerns regarding gated versus nongated cardiac CT and advantages and concerns regarding the use of breast shields in girls undergoing cardiac CT imaging.

2011-01-01

107

P2X1 receptor mobility and trafficking; regulation by receptor insertion and activation

Ocean waves: energy resource assessment

P2X1 receptors for ATP contribute to signalling in a variety of cell types and following stimulation undergo rapid desensitisation (within 1 s), and require ∼5 min to recover. In HEK293 cells...Full Text Available

2010-06-01

108

Loss of light charged particles by nuclear interactions in BaF[sub 2] crystals

The aim of this paper is to provide a general view of wave energy resource assessment. First, a review of the origin of waves and the transformation they undergo as they propagate towards the coast through waters of decreasing depth is presented. Following this, the wave and wave-energy parameters and the statistics required for resource characterization are described. The various types of wave data and their usefulness for the present purposes are summarised. A common methodology for assessment of the wave energy resource is developed. Finally, a general description of the global open ocean resource is presented.

2002-12-31

109

Identification of a nuclear-localized nuclease from wheat cells undergoing programmed cell death that is able to trigger DNA fragmentation and apoptotic morphology on nuclei from human cells

The nuclear interaction probability of light charged particles in BaF[sub 2] crystals has been studied as a function of the incident particle energy. Light charged particles were identified in charge and mass by measuring their magnetic rigidity and their time-of-flight. The percentage of particles undergoing nuclear interactions has been measured for particles of charge from Z=1 to Z=6 and the experimental data are compared with the results of a model calculation. (orig.)

1993-07-15

110

Genome-wide analysis reveals rapid and dynamic changes in miRNA and siRNA sequence and expression during ovule and fiber development in allotetraploid cotton (Gossypium hirsutum L.)

PCD (programmed cell death) in plants presents important morphological and biochemical differences compared with apoptosis in animal cells. This raises the question of whether PCD arose independently...Full Text Available

2006-08-01

111

Future research on transonic unsteady aerodynamics and its aeroelastic applications

BackgroundCotton fiber development undergoes rapid and dynamic changes in a single cell type, from fiber initiation, elongation, primary and secondary wall biosynthesis, to fiber...Full Text Available

2009-01-01

112

Environmentally-Induced Malignancies: An In Vivo Model to Evaluate the Health Impact of Chemicals in Mixed Waste

The workshop focused on strategies for promoting and developing engineering level transonic flutter prediction techniques. The technology of transonic aerodynamics is currently undergoing rapid development. Significant progress is being made to solve the inherently nonlinear equations describing unsteady motions of wings in transonic flow, while the availability of reliable and efficient computational methods will greatly enhance the ability to predict the aeroelastic behavior of modern aircraft operating under transonic flow conditions.

1987-08-01

113

Endocavitary radiotherapy of rectal tumours; Endokavitaer straalebehandling ved distale rectum tumorers

Occupational and environmental exposure to organic ligands, solvents, fuel hydrocarbons, and polychlorinated biphenyls are linked with increased risk of hematologic malignancies. DOE facilities and waste sites in the U.S. are contaminated with mixtures of potentially hazardous chemicals such as metals, organic ligands, solvents, fuel hydrocarbons, polychlorinated biphenyls and radioactive isotopes. A major goal of this project was to establish linkage between chemical/radiation exposure and induction of genomic damage in target populations with the capability to undergo transformation.

2001-05-04

114

Electrophilic addition of astatine

The authors describe their experience of endocavitary radiotherapy of adenomas and carcinomas of the lower rectum. The method is an alternative for patients who cannot undergo standard surgical procedure or do no want a permanent colostomy. This method is cheap, fast and causes little discomfort to the patients, gives reasonable long-term results and has low morbidity. 11 refs., 4 figs., 2 tabs.

1997-02-01

115

Developing Seeds of Ricinus communis L., When Detached and Maintained in an Atmosphere of High Relative Humidity, Switch to a Germinative Mode without the Requirement for Complete Desiccation

It has been shown for the first time that astatine is capable of undergoing addition reactions to unsaturated hydrocarbons. A new compound of astatine, viz., ethylene astatohydrin, has been obtained, and its retention numbers of squalane, Apiezon, and tricresyl phosphate have been found. The influence of various factors on the formation of ethylene astatohydrin has been studied. It has been concluded on the basis of the results obtained that the univalent cations of astatine in an acidic medium is protonated hypoastatous acid.

116

Current results from the Texas A and M electron beam ion source

Immature seeds of castor bean (Ricinus communis) removed from the capsule at 25 to 40 days after pollination (25-40 DAP) and placed in an atmosphere of high relative humidity undergo...Full Text Available

1989-06-01

117

Australian Studies in Europe and the Omnipresent Elephant

The electron beam ion source (EBIS) at Texas A and M University was constructed and is currently undergoing tests on the injection and transmission of the electron beam through the solenoid. Results of computer simulation of the electron beam are presented, as well as measurements of electron beam profiles using a pinhole beam analyzer.

118

DEFF Research Database (Denmark)

Australian Studies has to undergo a transformation from its overtly literary focus to a more interdisciplinary approach, if it is to have a viable future. Rather than seeing this as a moment of unproductive stalemate, the article argues for the advantages in developing such a new focus. Also the article considers the historical evolution of Australian Studies in Europe.

2009-01-01

119

AGB (asymptotic giant branch): Star evolution

A randomized trial of microdose leuprolide acetate protocol versus luteal phase ganirelix protocol in predicted poor responders

Asymptotic giant branch stars are red supergiant stars of low-to-intermediate mass. This class of stars is of particular interest because many of these stars can have nuclear processed material brought up repeatedly from the deep interior to the surface where it can be observed. A review of recent theoretical and observational work on stars undergoing the asymptotic giant branch phase is presented. 41 refs.

1987-01-01

120

British Library Electronic Table of Contents (United Kingdom)

We performed a randomized trial to compare IVF outcomes in 54 poor responder patients undergoing a microdose leuprolide acetate (LA) protocol or a GnRH antagonist protocol incorporating a luteal phase E2 patch and GnRH antagonist in the preceding menstrual cycle. Cancellation rates, number of oocytes retrieved, clinical pregnancy rates (PR), and ongoing PRs were similar between the two groups.

2011-01-01

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121

Routine upfront abciximab versus standard periprocedural therapy in patients undergoing primary percutaneous coronary intervention for cardiogenic shock: The PRAGUE-7 Study. An open randomized multicentre study

British Library Electronic Table of Contents (United Kingdom)

Background: The outcome of acute myocardial infarction (AMI) complicated with cardiogenic shock is poor. The aim of this study was to analyse, whether upfront abciximab administration could improve the outcomes of cardiogenic shock. Methods: This multicentre open trial randomized 80 patients with AMI complicated by cardiogenic shock expected to undergo primary PCI into group A (routine upfront-pre-procedural-abciximab bolus followed by 12-h abciximab infusion) and group B (standard therapy). The study primary objective was 30-day combined outcome (death/reinfarction/stroke/new severe renal failure). Results: PCI was technically successful in 90% (A) versus 87.5% (B) patients. Abciximab was used in 100% (A) versus 35% (B). The primary endpoint occurred in 17 group A patients (42.5%) and 11 ...

2011-01-01

122

Mean glandular doses for women undergoing mammographic breast screening in Oyo state, Nigeria

British Library Electronic Table of Contents (United Kingdom)

In this work, thermoluminescent dosimeters have been used to measure entrance surface doses (ESDs) of patients undergoing mammographic screening at the University College Hospital, Ibadan, Oyo state. The mean glandular doses (MGDs) were also calculated using the measured ESDs. The results showed that the ESDs ranged from 0.26mGy to 21.26mGy for the mediolateral oblique (MLO) views and 0.08mGy to 5.36mGy for the craniocaudal (CC) views. The calculated MGD ranged from 0.07mGy to 3.57mGy for the MLO views and 0.02mGy to 0.98mGy for the CC views. The possible reasons for the large variations in the individual ESD values and MGD values for both views are discussed using patients data, equipment specific data and the technical parameters used for the examinations. Comparison showed that the mean...

2009-01-01

123

Femoral neck buttressing: a radiographic and histologic analysis

[Changes in ecological features of soils after controlled fires in forests defoliated by the Siberian moth in the southern taiga subzone of the Enise? Region, Siberia].

Objective. To examine the incidence, radiographic and histologic findings of medial femoral neck buttressing in a consecutive group of patients undergoing total hip arthroplasty.Design. Biomechanical parameters were evaluated on standard anteroposterior pelvic radiographs of 113 patients prior to hip replacement surgery. Demographic information on all patients was reviewed and histologic evaluation was performed on specimens obtained at the time of surgery.Results. The incidence of medial femoral neck buttressing was found to be 50% in a consecutive series of patients undergoing total hip arthroplasty. The incidence was slightly higher in women (56% vs 41%). Patients with buttressing had increased neck-shaft angles and smaller femoral neck diameters than were seen in patients without buttressing. Histologic evaluation demonstrated that the buttress resulted from deposition bone by the periosteum on the femoral neck in the absence of any ...

2000-10-01

124

Zephyr: A secure Internet process to streamline engineering

Data on the postfire dynamics of soil properties in the foci of Siberian moth population outbreaks are considered. It has been shown that controlled fires set in pest-defoliated forests result in the loss of approximately 75% of carbon and 50% of nitrogen from the forest litter through their emission into the atmosphere and in the enrichment of the upper soil horizons with potassium and phosphorus (this concerns both total and movable forms). Microbiological processes in the organogenic horizon undergo significant transformation, the density of microarthropods decreases, and the abundance of mites becomes hundreds of times lower. PMID:15354965

125

White dwarf evolution - Cradle-to-grave constraints via pulsation

Lawrence Livermore National Laboratory (LLNL) is implementing an Internet-based process pilot called `Zephyr` to streamline engineering and commerce using the Internet. Major benefits have accrued by using Zephyr in facilitating industrial collaboration, speeding the engineering development cycle, reducing procurement time, and lowering overall costs. Programs at LLNL are potentializing the efficiencies introduced since implementing Zephyr. Zephyr`s pilot functionality is undergoing full integration with Business Systems, Finance, and Vendors to support major programs at the Laboratory.

1998-05-12

126

Value of computed Tomography in re-staging patients undergoing second-look laparotomy for ovarian cancer

White dwarf evolution, particularly in the early phases, is not very strongly constrained by observation. Fortunately, white dwarfs undergo nonradial pulsation in three distinct regions of the H-R diagram. These pulsations provide accurate masses, surface compositional structure and rotation velocities, and help constrain other important physical properties. We demonstrate the application of the tools of stellar seismology to white dwarf evolution using the hot white dwarf star PG 1159-035 and the cool DAV (or ZZ Ceti) stars as examples. From pulsation studies, significant challenges to the theory of white dwarf evolution emerge. 44 refs.

1990-05-28

127

The European energy market and environmental considerations: Options for Norwegian industry

Twenty-five patients with ovarian carcinoma who had been operated and treated with chemotherapy underwent clinical examination and CT before reintervention (second-look laparotomy) to detect the presence of eventual recurrences. The prediction of recurrence based on CT and clinical findings was compared with the surgical findings at reintervention. CT proved to be more accurate than clinical examination in detecting recurrences; this was especially true for masses in the abdominal cavity, with the exception of small peritoneal nodules. The authors suggest the use of CT for staging the patients candidate to reintervention. This might help to avoid reintervantion in patients with persistent disease and to plan treatment.

1991-01-01

128

Structural Phase Transition in AuZn Alloys

The power industry is undergoing major changes. Deregulation and a competitive climate demand effective solutions. Costs and losses must be reduced, and overall efficiency must be raised. Industrial options connected to energy market and environmental considerations are discussed. Themes discussed in this paper are environmental challenges, the fuel factor, power plants in use today, the Norwegian power system, the European system, power exchange across borders, the transmission system, the future European system, and options for Norwegian industry. 27 figs.

1995-12-31

129

Results of thermal performance evaluation of the Owens-Illinois Sunpak liquid solar collector at indoor conditions

AuxZn1-x alloys undergo a shape memory martensitic transformation whose temperature and nature (continuous or discontinuous) is strongly composition dependent. Neutron diffraction experiments were performed on single crystals of x=50 and 52 to explore the structural changes occurring at the transition temperature. A transverse modulation with wavevector q0=(1/3,1/3,0) develops below the transition temperature, with no observable change in lattice parameter. However, the Bragg peak width shows a broadening suggesting an unresolved rhombohedral distortion similar to what has been observed in NiTi-Fe alloys.

2009-05-03

130

Prospective, observational study of the depth of anesthesia during oocyte retrieval using a total intravenous anesthetic technique and the Bispectral index monitor

This report provides test results on the thermal performance of an Owens-Illinois Sunpak liquid, evacuated tube, solar collector under simulated conditions. The test was conducted using the Marshall Space Flight Center Solar Simulator in accordance with the test requirements specified in ASHRAE 93-77 (Method of Testing to Determine the Thermal Performance of Solar Collectors) and the procedures contained in MTCP-FA-SHAC-400 (Procedure for Operation of the MSFC Solar Simulator Facility). The tests were performed on a module used on the early demonstration projects. A current production module is undergoing tests with results to be in a subsequent report.

1979-10-10

131

British Library Electronic Table of Contents (United Kingdom)

Fifty patients scheduled to undergo IVF received a standard anesthetic of fentanyl and propofol for induction, followed by propofol infusion, with Bispectral index values and modified Ramsey sedation scores recorded at 5-minute intervals for the duration of anesthesia care. Moderate sedation was found only transiently during the first 5-10 minutes of the oocyte retrieval, but thereafter the level of sedation increased, with deep sedation and general anesthesia measured in all patients as determined by both the Bispectral index scores and lack of response to painful stimulation.

2011-01-01

132

Phenomenological modeling of the stress-strain behaivor of ceramic matrix composites with application to stress analysis

Nitrogen oxides decreasing combustion method

A plane stress constitutive relation is developed for laminate composites undergoing matrix cracking and therefore displaying significant nonlinear stress-strain behavior. The constitutive relation is similar in some respects to a phenomenological theory of plasticity in that it is fit to data from uniaxial tests. The constitutive equations are specialized to brittle matrix composites (especially CMCs) in the form of cross-piles and quasi-isotropic laminates. Several problems involving stress redistribution at holes and notches due to nonlinear stress-strain behavior are investigated with the aid of the constitutive law.

1995-12-31

133

Nitrogen oxides decreasing combustion method

A nitrogen oxides decreasing combustion method comprising: mixing a fuel and air with each other; bringing the mixture obtained into contact with a packed catalyst; and adding a fresh supply of the fuel to the stream obtained to form a mixed gas and causing the mixed gas to undergo non-catalytic thermal combustion, characterized in that only a catalytic reaction or combustion occurs at the packed catalyst; the temperature of the packed catalyst is kept lower than the ignition temperature of the mixture; the adiabatic flame temperature which is reached by the non-catalytic thermal combustion of the mixed gas is lower than the temperature at which the nitrogen oxides occur. 39 figs.

1988-10-19

134

Low-energy fission of nuclei lighter than Hg

This patent describes a nitrogen oxides decreasing combustion method which comprises: a first step of mixing a fuel and air with each other; a second step of bringing the mixture obtained in the first step into contact with a packed catalyst such that only catalytic combustion occurs; and a third step of adding a fresh supply of the fuel to a stream obtained from the second step to form a mixed gas and causing the mixed gas to undergo non-catalytic thermal combustion. The temperature of the packed catalyst is lower than the ignition temperature of the mixture and the adiabatic flame temperature of the mixed gas is lower than a temperature at which the nitrogen oxides occur.

1988-03-22

135

Investigation of cause of cracking of high-strength 30HGSNA grade steel subjected to stresses and corrosive agents

The mass and energy distributions for low-energy p- and alpha-particle induced fission of "1"8"7","1"8"8Ir and "1"9"5Au and "3He-induced fission of sufficiently heated "1"8"8Ir and "1"9"4Au have been measured with use of fast spectrometer of complementary fragments. From Au to Ir, the shape of the mass distributions undergoes substantial changes related to specific dependence of the saddle shell corrections on A and Z fissioning nuclei. The results are compared with theoretical predictions.

136

Investigation of FP paths during hypothetical severe accident as a result of Small Break LOCA of WWER-1000 reactor type

It has been found out that 30HGSNA steel undergo cracking under action of stresses in aqueous solutions containing oxygen, while it show high resistance in deoxidated solutions. The purpose of such phenomena is the existence of sulfur inclusions in steel which are a centers of denting corrosion. That points acting as a stresses concentrators where pH factor decreases including hydrogen formation and its absorption in the metal. That mechanism is the main purpose of brittle steel cracking observed in oxygen rich solutions. (author).

1995-05-17

137

Infrared spectroscopy analysis of MgO-doped silicon nitride

Modelling the behaviour of fission product (FP) in a nuclear reactor coolant system (RCS) undergoing a hypothetical severe accident is an important step in the evaluation of radioactive release outside a nuclear power plant. This paper scrutinize Small Break LOCA sequence for WWER1000 reactor in order to investigate the possible paths for release of FP from fuel pallets to the reactor containment. Contemporaneous computer code for simulation of RCS will be use for the analysis. The results from analysis of fuel damage and release of FP trough the break of cold leg are present. (author)

2006-04-01

138

High pressure study of AlP: Transformation to a metallic NiAs phase

Silicon nitride hybrid ball bearings used in high temperature applications undergo mechanical and environmental degradation. To study the surface chemistry of silicon nitride, a CAChe{trademark} Worksystem* has been used to generate the clusters and corresponding transmission vibrational spectra of silicon nitride. In the present study, the effect of surface conditions on the surface chemistry and wear degradation of silicon nitride was evaluated. Infrared reflection spectroscopy (IRRS) used to determine molecular orientations shows a difference in reflectance spectra for fractured and as-received.

1997-12-31

139

Emission of photons by electrons and positrons passing through a thin single crystal

The crystal structure and optical reflectivity of AlP has been studied in a diamond anvil cell using energy dispersive x-ray diffraction to 43 GPa and micro-optical reflectance spectroscopy to 36 GPa. AlP undergoes a first order phase transformation from zincblende to a NiAs structure which exhibits metallic reflectivity in the near-infrared. The decrease in volume on transformation is 17%[plus minus]1%. The transformation is reversible but has large hysteresis. The equilibrium transformation pressure is 9.5[plus minus]5 GPa.

1994-12-01

140

Electron microscopy analysis of grain boundary structure and composition in superplastically deformed Al-Mg alloys

We consider the radiation of particles (electrons and positrons) undergoing planar channeling in a single crystal of small thickness L. We show that for Lapprox...pi..b/theta/sub L/, where b is the lattice constant and theta/sub L/ is the Lindhard angle, in addition to the principal maxima of spontaneous radiation of channeled particles in the spectrum there are additional interference maxima, and the positions of all maxima of the radiation intensity depend on L. We discuss the dependence of the intensity of radiation at various frequencies on the crystal thickness.

1984-07-01

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141

Effect of isopropyl alcohol on the surface localization and recombination of conduction-band electrons in Degussa P25 TiO_2. A pulse-radiolysis time-resolved microwave conductivity study

Evaluation of grain boundary composition and structure in superplastically deformed AA5083-based alloys (Al-4.5Mg-1.6Mn-0.2Zr) was carried out in a field-emission gun transmission electron microscope (FEG-TEM). During superplastic deformation at high homologous temperatures materials undergo extensive grain boundary sliding (GBS) which creates a flow of defects in the near-boundary region. Recent literature has shown that the grain-boundary composition in Al-Mg alloys is not necessarily the same as the matrix, and that these differences can have an effect on GBS.

1996-12-31

142

Bone geometry, biomechanics, and mineral content of the distal radius in uremic patients with severe hyperparathyroidism; Valutazione delle proprieta' geometriche, biomeccaniche e osteodensitometriche del radio ultradistale mediante tomografia computerizzata quantitativa periferica nei pazienti uremici affetti da iperparatiroidismo grave

Conduction-band electrons, formed by pulse radiolysis of Degussa P25 TiO_2 particles, have been monitored by time-resolved microwave conductivity and found to undergo equilibrium localization and eventual recombination at the particle surface. In the presence of isopropyl alcohol recombination is retarded due to surface hole scavenging. The particle bulk can then be pumped with mobile electrons, which survive for seconds.

143

Anesthetic considerations for nontransplant procedures in lung transplant patients

Bone integrity and mineral status were studied with a noninvasive method in uremic patients with severe secondary hyperparathyroidism undergoing maintenance hemodialysis. [Italian] Gli autori propongono un metodo non invasivo per studiare la densita' minerale e le caratteristiche geometriche e biomeccaniche dell'osso nei pazienti uremici affetti da iperparatiroidismo secondario grave.

1999-04-01

144

British Library Electronic Table of Contents (United Kingdom)

Lung transplantation has become an accepted option for many patients with end-stage pulmonary diseases. Anesthesia and surgery following lung transplantation may be required for various diseases that may affect both systemic organs and the transplanted graft. When a patient with a lung transplant undergoes surgery, there is the potential for interference with lung function, depending on the type of intervention and its anatomical site. Accurate preoperative evaluation, an understanding of the physiology of the transplanted lung, proper airway instrumentation, individualized management of intraoperative ventilation, and fluid balance are essential for a positive perioperative outcome.

2011-01-01

145

Improved detection of myocardial infarction with technetium-99m stannous pyrophosphate and serum MB creatine phosphokinase

Woven polydioxanone biodegradable stents: a new treatment option for benign and malignant oesophageal strictures

The relative sensitivity and combined value of myocardial technetium-99m stannous pyrophosphate imaging and determinations of serum MB creatine phosphokinase (the ''myocardial'' CPK isoenzyme) in detecting acute myocardial infarction were evaluated in 41 patients with suspected infarction and 23 patients recovering from cardiac surgery. In the patients with suspected infarction, myocardial infarction was confirmed in 25 and was consistently associated with increased serum MB CPK. Abnormal radionuclide images were obtained in 23 of 25 patients (92%)) with definite myocardial infarction and in 2 of 16 patients without confirmed infarction. Although the localization of infarction by imaging correlated well with the localization by electrocardiogram, infarct size estimated by imaging did not correlate well with estimates based on peak total serum CPK activity or serial changes in CPK activity. Serum MB CPK activity increased after cardiac surgery in 6 patients ...

146

Usefulness of routine laboratory parameters in the decision to treat refractory cardiac arrest with extracorporeal life support

We present our initial experience with a new biodegradable (BD) esophageal stent in two patients, one for a therapy-resistant benign esophageal stricture, and the other as a temporary measure during curative radiotherapy for oesophageal carcinoma. The BD stents need to be loaded into a conventional pull-back delivery system but are then placed in a standard fashion. Pre-dilatation should be avoided to reduce the risk of migration, however if migration occurs the stents can be left to dissolve in the stomach. The stents are radiolucent but easily identified on CT with minimal artefact and thus might even aid with radiotherapy planning. BD stents offer an exciting new strategy for therapy-resistant benign strictures as well as a supportive measure for oesophageal cancer undergoing non-surgical treatment. (orig.)

2010-05-01

147

British Library Electronic Table of Contents (United Kingdom)

Aim: To evaluate the usefulness of routine laboratory parameters in the decision to treat refractory cardiac arrest patients with extracorporeal life support (ECLS). Methods: Sixty-six adults with witnessed cardiac arrest of cardiac origin unrelated to poisoning or hypothermia undergoing cardiopulmonary resuscitation without return of spontaneous circulation (duration: 155min [120-180], median, [25-75%-percentiles]) were included in a prospective cohort-study. ECLS was implemented under cardiac massage, using a centrifugal pump connected to a hollow-fiber membrane-oxygenator, aiming to maintain ECLS flow >=2.5l/min and mean arterial pressure >=60mmHg. Results: Forty-seven of 66 patients died within 24h from multiorgan failure and massive capillary leak. Of 19/66 patients who survived >=24h...

2011-01-01

148

Unfolding analysis of the mature and unprocessed forms of Bacillus licheniformis ?-glutamyltranspeptidase

British Library Electronic Table of Contents (United Kingdom)

Bacillus licheniformis ?-glutamyltranspeptidase (BlGGT) undergoes an autocatalytic process to generate 44.9 and 21.7?kDa subunits; however, a mutant protein (T399A) loses completely the processing ability and mainly exists as a precursor. For a comprehensive understanding of their structural features, the biophysical properties of these two proteins were investigated by circular dichroism and fluorescence spectroscopy. Tryptophan fluorescence and circular dichroism spectra were nearly identical for BlGGT and T399A, but unfolding analyses revealed that these two proteins had a different sensitivity towards temperature- and guanidine hydrochloride (GdnHCl)-induced denaturation. BlGGT and the unprocessed T399A displayed T m values of 61.4?C and 68.1?C, respectively, and thermal unfolding of b...

2011-01-01

149

Trade curtailment schemes for the security control of the transmission network in a deregulated environment

Thyroid cancer stem cells

Due to deregulation, the electrical power industry is undergoing deep changes, moving towards an open market. Two kinds of parties are active in the new environment: the economical agents (producers, consumers, brokers) and the power system operator, the former interested in power exchanges and their economic value, the latter in bus injections and their threat to the security of the transmission network. The variables used to model the transmission network operation have to be meaningful to the power system operator as well as to the economical parties; the action rules followed by the power system operator to enforce network security have to be carefully designed to be equitable and non-discriminatory. In this paper, a modeling of the power exchanges is proposed in the form of multilateral trades, and some rules for the action of the power system operator are proposed and discussed. The results obtained on a simple study case are discussed. (Author)

2002-01-01

150

British Library Electronic Table of Contents (United Kingdom)

Thyroid cancer is the most frequently diagnosed endocrine cancer and causes more deaths than all other endocrine cancers combined. Research findings support the concept that a subpopulation of thyroid cancer cells displays properties characteristic of stem cells. These putative cancer-forming entities drive tumorigenesis as a result of their dual ability to undergo self-renewal and to differentiate into various types of cancer cells; they also mediate metastasis and are resistant to the effects of chemotherapy and radiation therapy. This Review discusses the cellular origin of thyroid cancer and the properties of the thyroid cancer stem cell niche. The article critically evaluates the methods used to identify molecular markers expressed by thyroid-cancer-initiating cells and outlines prosp...

2011-01-01

151

Thermoluminescent (Tl) dosimetry of slow-neutron fields at radiotherapy dose level

The silver catalyst process for converting methanol to formaldehyde - kinetic investigations

The dosimetry for radiotherapy involving neutrons is very complicated, owing to the complexity of secondary radiation components, whose contributions to the total absorbed dose have to be discriminated, owing to the different radiobiological effects. In order to separate thermal neutrons and photons, LiF dosimeters are mostly utilized. containing different percentage of Li, like as TLD-700, TLD-100 and TLD-600, but many problems arise. In the response of TLD-700 exposed to neutron-gamma mixed fields with high neutron flux, the contribution of thermal neutrons to the Tl emission is high. Moreover. TLD-100 and TLD-600 may undergo radiation damage, and great care has to be taken in order to obtain reliable results. Other TLDs showing lower sensitivity to neutrons are proposed and experimented for such high-flux neutron fields. The faced problems and various proposed solutions are here described. (Author)

2003-07-01

152

The effect of lidocaine, bupivacaine and ropivacaine in nasal packs on pain and hemorrhage after septoplasty

In pre-experiments a tubular reactor was checked whether it is suitable for kinetic measurement on the system of the silver-catalysed partial oxidation of methanol to formaldehyde. Detrimental effects of heat-transfer and mass-transfer on the experimental results were ruled out. Investigations on the characteristics of the reaction showed that it is possible to manipulate the composition of the product mixture by changing the inlet concentration of the reactants. A modified power-law model was established to describe the reaction kinetics. It considers the preadsorption step of oxygen on the catalysts surface and fits the experimental data quite well. During the rapid oxidation the catalysts surface undergoes a drastic change. It gets coarse and has an adsorption capacity of 11 m{sup 2}/g after being exposed to the reaction mixture. (orig.)

1998-12-31

153

British Library Electronic Table of Contents (United Kingdom)

We aimed to investigate the effects of local anesthetics soaked in Merocel nasal packs on hemorrhage and pain after septoplasty. The methodology includes a prospective double-blind study that was conducted in patients undergoing septoplasty because of nasal septal deviation. The study included 143 patients. The patients were divided into four groups. Each group received 1% lidocaine?+?0.000625% adrenalin, 0.375% ropivacaine, 0.25% bupivacaine as study groups or 0.9% sodium chloride as a control group in their Merocel packs postoperatively. The local anesthetics or sodium chloride were reapplied at the eighth postoperative hour. Each patient was given a questionnaire where verbal analog score and amount of postoperative hemorrhage was noted. The statistical analysis was performed using two ...

2011-01-01

154

Technical Standards for Wolsong Unit 1 Nuclear Power Plant

Synchrotron radiation from electron beams in plasma-focusing channels.

More than twenty years after commencing commercial operation in 1983, Wolsong Unit 1(W1- NPP), the first CANDU Pressurized Heavy Water Reactor (PHWR) in Korea, has been undergoing refurbishment. Safety analyses were required to evaluate the safety of W1-NPP because significant amount of equipment has been refurbished. To evaluate the effectiveness of W1-NPP after these upgrades, new safety analyses were performed using the same technical standards of Wolsong Units 2, 3, 4 (W234-NPP) for Design Basis Accidents (DBA). The refurbished W1- NPP is expected to be licensed for full power operation based on the verified safety analysis results that are obtained by using the upgraded computer codes and newly adopted technical standards of W234-NPP

2010-10-01

155

Studies of accelerated compact toruses

Spontaneous radiation emitted from relativistic electrons undergoing betatron motion in a plasma-focusing channel is analyzed, and applications to plasma wake-field accelerator experiments and to the ion-channel laser (ICL) are discussed. Important similarities and differences between a free electron laser (FEL) and an ICL are delineated. It is shown that the frequency of spontaneous radiation is a strong function of the betatron strength parameter a(beta), which plays a role similar to that of the wiggler strength parameter in a conventional FEL. For a(beta) > or approximately 1, radiation is emitted in numerous harmonics. Furthermore, a(beta) is proportional to the amplitude of the betatron orbit, which varies for every electron in the beam. The radiation spectrum emitted from an electron beam is calculated by averaging the single-electron spectrum over the electron distribution. This leads to a frequency broadening of the radiation spectrum, which places ...

2002-05-20

156

Structure formation and the origin of dark energy

In an earlier publication we considered acceleration of plasma rings (Compact Torus). Several possible accelerator configurations were suggested and the possibility of focusing the accelerated rings was discussed. In this paper we consider one scheme, acceleration of a ring between coaxial electrodes by a B/sub theta/ field as in a coaxial rail-gun. If the electrodes are conical, a ring accelerated towards the apex of the cone undergoes self-similar compression (focusing) during acceleration. Because the allowable acceleration force, F/sub a/ = kappaU/sub m//R where (kappa < 1), increases as R/sup -2/, the accelerating distance for conical electrodes is considerably shortened over that required for coaxial electrodes. In either case, however, since the accelerating flux can expand as the ring moves, most of the accelerating field energy can be converted into kinetic energy of the ring leading to high efficiency.

1983-01-04

157

Spike-train bifurcation scaling in two coupled chaotic neurons

Cosmological constant a.k.a. dark energy problem is considered to be one major challenge in modern cosmology. Here we present a model where large scale structure formation causes spatially-flat FRW universe to fragment into numerous `FRW islands' surrounded by vacuum. We show that this mechanism can explain the origin of dark energy as well as the late time cosmic acceleration. This explanation of dark energy does not require any exotic matter source nor an extremely fine-tuned cosmological constant. This explanation is given within classical general relativity and relies on the fact that our universe has been undergoing structure formation since its recent past.

2007-01-01

158

Somatic and genetic radiation exposure of the patient in digital subtraction angiography (DSA)

We investigate the variation of the out-of-phase periodic rhythm produced by two chaotic neurons {bold (}Hindmarsh-Rose neurons [J. L. Hindmarsh and R. M. Rose, Proc. R. Soc. London B {bold 221}, 87 (1984)]{bold )} coupled by electrical and reciprocally synaptic connections. The exploration of a two-parametric bifurcation diagram, as a function of the strength of the electrical and inhibitory coupling, reveals that the periodic rhythms associated to the limit cycles bounded by saddle-node bifurcations, undergo a strong variation as a function of small changes of electrical coupling. We found that there is a scaling law for the bifurcations of the limit cycles as a function of the strength of both couplings. From the functional point of view of this mixed typed of coupling, the small variation of electrical coupling provides a high sensitivity for period regulation inside the regime of out-of-phase synchronization. {copyright} {ital 1997} {ital The American Physical ...

1997-03-01

159

Smart pigs root out pipeline problems

The somatic and genetic radiation exposure of patients undergoing Digital Subtraction Angiography (DSA) and traditional Film Arteriography (FA) of cranial, cervical, thoracic and abdominal vascular territories are compared. The radiation doses absorbed within the critical organs - red bone marrow, lung, thyroid gland and female breast - and in the gonads were measured using an anthropomorphic Alderson phantom. A Somatic Dose Index was calculated in order to estimate the somatic radiation risk. The somatic radiation exposure depends upon the location of the critical organs with respect to the entrance site of the x-ray beam, and can be reduced by an appropriate choice of the angiographic projection. Under this condition, the radiation exposure of the patient during DSA can be lower than during FA. For renal DSA an a.p. projection, the use of an abdominal compression device and careful caudal shielding of the field are advocated. (orig.).

1986-01-01

160

Simultaneous Liver-Kidney Versus Liver Transplantation Alone in Patients with End-Stage Liver Disease and Kidney Dysfunction Not on Dialysis

In the world of pipeline maintenance, there are pigs and there are intelligent pigs. Intelligent pigs, when launched into a pipeline, carry instrumentation onboard which enables them to gather and record information about problems such as denting, corrosion, and cracking. More basic pigs, on the other hand, look after the routine internal maintenance chores such as cleaning and swabbing, or else perform operational duties such as batching different types of product along the line. The harsh environment in which pigs often operate is described. Aside from the mechanical shocks they undergo when passing welds, bends, and other fittings, they may have to contend with hostile conditions such as hydrogen sulfide environments. High pressure is another factor to consider. In crude oil lines, significant paraffin deposits also can cause problems if they affect the sensors ability to maintain good contact with the pipe wall. In spite of these considerations, increasing ...

1983-12-01

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161

British Library Electronic Table of Contents (United Kingdom)

BackgroundSince implementation of the Model for End-stage Liver Disease (MELD), the number of simultaneous liver-kidney transplantations (SLKT) has increased in the United States. However, predictors and survival benefit of SLKT compared to liver transplantation alone (LTA) are not well defined. MethodsOrgan Procurement and Transplantation Network data of patients with end-stage liver disease (ESLD) with estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2 who had not been on dialysis while on the waiting list and underwent liver transplantation between 2002 and 2008 were analyzed. To identify predictors of undergoing SLKT versus LTA, multiple logistic regression analysis was performed. Cox proportional hazards regression analysis was used to assess the association between...

2011-01-01

162

Security features of a nuclear material accounting system

Response to measles-mumps-rubella vaccine in children on dialysis.

The Los Alamos Nuclear Material Accounting and Safeguards System (MASS) is a near-real-time accountability system for bulk materials, discrete items, and material undergoing dynamic processing. MASS has evolved from an eighty-column card based process control system to a very sophisticated computer system. The security of the MASS computer system is provide through various access controls. There are two kinds of access control to be addressed. They are physical access control to the hardware which make up the system, and access control to the software. There are many features which provide a measure of security to the hardware that will be discussed. Access to the software is controlled by a security password. Access to various transaction activities in the system is controlled through the level of MASS user privilege. Details of MASS user privilege will be discussed.

1988-01-01

163

Real-time neutron scattering investigations of biological signal transduction dynamics

Ten children receiving maintenance dialysis were immunized with the standard dose of measles-mumps-rubella vaccine between 15 and 33 months of age. Immune responses to vaccination were determined using commercially available enzyme-linked immunosorbent assays for measles, mumps, and rubella viruses. Eight children responded to measles vaccine, 5 to mumps vaccine, 8 to rubella vaccine, and only 3 children to all three vaccines, compared with a seroconversion rate of over 90% to all three vaccines in healthy children (P less than 0.0001). We contend that the relatively poor immunocompetence of our dialysis patients explains their less than optimal vaccine response and suggest that children vaccinated while undergoing dialysis be tested to confirm serological evidence of immunity. PMID:1571219

1992-03-01

164

Real-time neutron scattering investigations of biological signal transduction dynamics

During their catalytic cycle, proteins involved in biological signal transduction undergo unexpectedly large conformational changes, which are at the core of their biological functioning. Until now it has been extremely difficult to obtain experimental insight into the nature of these conformational changes. Mathematical modeling and time-resolved X-ray crystallography have resulted in probable routes along which these conformational changes may take place, but so far this fundamental biological phenomenon has hardly been tackled experimentally. Here, we report on an attempt to observe structural changes in Photoactive Yellow Protein with time-resolved small-angle neutron scattering using diffractometer D22 at the high-flux reactor of the Institut Laue-Langevin, Grenoble, France.

2005-07-01

165

RADIONUCLIDE DATA PACKAGE FOR PERFORMANCE ASSESSMENT CALCULATIONS RELATED TO THE E-AREA LOW-LEVEL WASTE FACILITY AT THE SAVANNAH RIVER SITE.

During their catalytic cycle, proteins involved in biological signal transduction undergo unexpectedly large conformational changes, which are at the core of their biological functioning. Until now it has been extremely difficult to obtain experimental insight into the nature of these conformational changes. Mathematical modeling and time-resolved X-ray crystallography have resulted in probable routes along which these conformational changes may take place, but so far this fundamental biological phenomenon has hardly been tackled experimentally. Here, we report on an attempt to observe structural changes in Photoactive Yellow Protein with time-resolved small-angle neutron scattering using diffractometer D22 at the high-flux reactor of the Institut Laue-Langevin, Grenoble, France

2005-04-11

166

Protective effects of long term dietary restriction on swimming exercise-induced oxidative stress in the liver, heart and kidney of rat

The Savannah River Site disposes of low-level radioactive waste within on-site engineered disposal facilities. The Savannah River Site must demonstrate that these disposals meet the requirements of DOE Order 435 . 1 through a process known as performance assessment (PA). The objective of this document is to provide the radionuclide -specific data needed for the PA calculations . This work is part of an on-going program to periodically review and update existing PA work as new data becomes available. Revision of the E -Area Low-Level Waste Facility PA is currently underway. The number of radionuclides selected to undergo detailed analysis in the PA is determined by a screening process. The basis of this process is described. Radionuclide-specific data for half-lives, decay modes, daughters, dose conversion factors and groundwater concentration limits are presented with source references and methodologies.

2007-03-20

167

British Library Electronic Table of Contents (United Kingdom)

In this study, we evaluated the hypothesis that long term dietary restriction would have beneficial effects on the oxidative stress and antioxidant enzyme systems in liver, heart and kidney in adult male rats undergoing different intensities of swimming exercise. Sixty male, Sprague-Dawley rats were assigned as either dietary restricted on every other week day (DR) or fed ad libitum (AL) groups, and each group was further subdivided into sedentary, endurance swimming exercise training (submaximal exercise) and exhaustive swimming exercise (maximal exercise) groups. Animals in the submaximal exercise group swam 5 days/week for 8 weeks, while maximal exercise was performed as an acute bout of exercise. In parallel with the increase in the intensity of the exercise, the degree of lipid peroxi...

2007-01-01

168

Prognostic factors for survival after surgery for adrenal metastasis

British Library Electronic Table of Contents (United Kingdom)

Aim To better define the indications for adrenalectomy for adrenal metastasis we have analysed factors predicting survival in our institutional series. Methods A consecutive series of 30 patients undergoing adrenalectomy for metastasis (1996-2007), excluding patients with simultaneous ipsilateral renal cell carcinoma (RCC), was studied. Metastases were regarded as synchronous (6 mo), depending on the interval after primary surgery. Survival was calculated from time of adrenalectomy and factors influencing survival were identified. Results The tumour diagnoses were RCC n = 9, malignant melanoma n = 5, non-small-cell lung cancer n = 5, colorectal carcinoma n = 4, foregut carcinoid n = 2, adrenocortical carcinoma, breast cancer, hepatocellular carcinoma, urothelial c...

2010-01-01

169

Pretransplant Predictors and Posttransplant Sequels of Acute Kidney Injury after Allogeneic Stem Cell Transplantation

British Library Electronic Table of Contents (United Kingdom)

Acute kidney injury (AKI) is a common complication after allogeneic stem cell transplantation (SCT). Although various risk factors for AKI have been reported, the influence of pretransplant comorbidity on the incidence of AKI has not been well investigated. We performed a retrospective analysis of 207 consecutive patients undergoing myeloablative or nonmyeloablative SCT between 2001 and 2009, using the hematopoietic cell transplantation-specific comorbidity index (HCT-CI) as a representative of pretransplant comorbidities. According to Risk, Injury, Failure, Loss, and End-stage kidney disease (RIFLE) criteria, 158 patients (76.3%) developed AKI, and 92 patients (44.4%) developed severe AKI (RIFLE class I or class F) within 100 days after SCT. The cumulative incidence of severe AKI within 1...

2011-01-01

170

Pressure-induced structural transitions in multi-walled carbon nanotubes

British Library Electronic Table of Contents (United Kingdom)

We demonstrate a novel cross-sectional deformation, called the radial corrugation, of multi-walled carbon nanotubes (MWNTs) under hydrostatic pressure. Theoretical analyses based on the continuum elastic approximation have revealed that MWNTs consisting of more than ten concentric walls undergo elastic deformations at critical pressure Formula Not Shown , above which the circular shape of the cross-section becomes radially corrugated. Various corrugation modes have been observed by tuning the innermost tube diameter and the number of constituent walls, which is a direct consequence of the core-shell structure of MWNTs. Cross-sectional views of MWNT under high hydrostatic pressure: elliptic deformation with the mode index n = 2 (left), and radial corrugations with n = 5 (center), and n = 6 ...

2009-01-01

171

Potential new approaches for the development of brain imaging agents for single-photon applications

Potential new approaches for the development of brain imaging agents for single-photon applications

This paper describes new strategies for the brain-specific delivery of radionuclides that can be used to evaluate regional cerebral perfusion by single photon imaging techniques. A description of several examples of interesting new strategies that have recently been reported is presented. A new approach at this institution for the brain-specific delivery of radioiodinated iodophenylalkyl-substituted dihyronicotinamide systems is described which shows good brain uptake and retention in preliminary studies in rats. Following transport into the brain these agents appear to undergo facile intracerebral oxidation to the quaternized analogues which do not recross the intact blood-brain barrier and so are effectively trapped in the brain. 49 refs., 9 figs., 1 tab.

1984-10-12

172

Noncentral extension of the $AdS_5 x S^5$ superalgebra supermultiplet of brane charges

The goals of this paper are to describe new strategies being pursued at several institutions for the brain-specific delivery of radionuclides that can be used to evaluate regional cerebral perfusion by single photon imaging techniques. A comprehensive review of the literature is beyond the scope of these proceedings and our goal is to, therefore, present a description of several examples of interesting new strategies that have recently been reported. In addition, the authors also describe a new approach being pursued at their institution for the brain-specific delivery of radioiodinated iodophenylaklyl-substituted dihydronicotiamide systems which shows good brain uptake and retention in preliminary studies in rats. Following transport into the brain these agents appear to undergo facile intracerebral oxidation to the quaternized analogues which do not cross the intact blood-brain-barrier and are effectively trapped in the brain.

173

NONLINEAR OPTICAL PHENOMENA: Nonlinear optical properties of colloidal silver nanoparticles produced by laser ablation in liquids

We propose an extension of the su(2,2|4) superalgebra to incorporate the F1/D1 string charges in type IIB string theory on the AdS_5 X S^5 background, or the electro-magnetic charges in the dual super Yang-Mills theory. With the charges introduced, the superalgebra inevitably undergoes a noncentral extension, as noted recently in [1]. After developing a group theoretical method of obtaining the noncentral extension, we show that the charges form a certain nonunitary representation of the original unextended superalgebra, subject to some constraints. We solve the constraints completely and show that, apart from the su(2,2|4) generators, there exist 899 complex brane charges in the extended algebra. Explicitly we present all the super-commutators among them.

2004-01-01

174

Multiple resonances and Coulomb blockade splitting in a quantum dot-DNA composite

The optical and nonlinear optical properties of colloidal solutions of silver obtained by laser ablation in water and ethanol are studied. It is shown that freshly prepared colloids experience a full or partial sedimentation by changing their nonlinear optical properties. Aqueous colloids undergo a partial sedimentation and their nonlinear optical absorption changes to nonlinear optical transmission. The obtained results are interpreted using the Drude model for metal particles taking the particle size into account and can be explained by the sedimentation of larger silver particles accompanied by the formation of a stable colloid containing silver nanoparticles with a tentatively silver oxide shell. The characteristic size of particles forming such a stable colloid is determined and its optical nonlinearity is estimated.

2004-07-01

175

British Library Electronic Table of Contents (United Kingdom)

Inspired by the recent realizations of quantum dot (QD)-DNA conjugation, we study the spectral density of a magnetic impurity coupled to a mesoscopic semiconducting host. Using a combination of exact diagonalization technique and an analytic approach, we demonstrate that various types of resonances occur according to the relative position of impurity levels (IL) with respect to the host levels (HL). While the usual Coulomb peaks appear when the IL lie inside a band gap, with IL approaching HL and hybridization activated, they shift nonlinearly with the repulsion strength and even undergo splitting for a strong hybridization. When IL merge into HL, multiple resonances of a comblike structure are found along with a parity effect.

2011-01-01

176

Moral Judgments Recruit Domain-General Valuation Mechanisms to Integrate Representations of Probability and Magnitude

British Library Electronic Table of Contents (United Kingdom)

Summary Many important moral decisions, particularly at the policy level, require the evaluation of choices involving outcomes of variable magnitude and probability. Many economic decisions involve the same problem. It is not known whether and to what extent these structurally isomorphic decisions rely on common neural mechanisms. Subjects undergoing fMRI evaluated the moral acceptability of sacrificing a single life to save a larger group of variable size and probability of dying without action. Paralleling research on economic decision making, the ventromedial prefrontal cortex and ventral striatum were specifically sensitive to the "expected moral value" of actions, i.e., the expected number of lives lost/saved. Likewise, the right anterior insula was specifically sensitive to outcome p...

2010-01-01

177

Moessbauer study of the firing process of the imitative ancient sky-blue Jun porcelain

Measurement of skin dose in primary irradiation of maxillary sinus carcinoma

Moessbauer spectra of the imitative ancient Jun porcelain indicate that the glaze and body materials contain Fe{sub 2}O{sub 3}, Fe{sub 3}O{sub 4} and structural iron. It is clear that during the firing process, the glaze undergoes dehydration, dehydroxylation, vitrification and recrystallization. The Fe{sup 2+} quadrupole splitting value of the paramagnetic peak of the body material is high even at low firing temperatures. For the body material, the distinction between dehydration and dehydroxylation is not clear. The changes of magnetism of the glaze and body materials in the firing process and the coloring mechanism of the sky-blue Jun porcelain are analyzed in the present paper. (orig.)

1994-11-01

178

Management of young onset colorectal cancer: divergent practice in the East of England

Subcutaneous involvement frequently occurs in maxillary sinus carcinoma. Radical resection does not include removal of the skin at risk. In standard postoperative wedge-pair treatment plans, the surface dose is dependent upon beam weighting, beam energy, and patient contour. Thermoluminescent dosimetry (TLD) measurements were performed to evaluate the surface dose of patients undergoing postoperative irradiation of maxillary sinus carcinoma following primary resection. When 60 Gy was delivered to isocenter with a 45 degrees wedge pair and 6 MV photons with 1 cm bolus, the subcutaneous tissues at risk received {approximately} 30 Gy. Based upon presented TLD measurements, supplemental electron beam therapy to the subcutaneous tissues if primarily involved should be considered.

1991-03-01

179

British Library Electronic Table of Contents (United Kingdom)

Abstract Aim- According to the revised Bethesda Guidelines, colorectal cancer (CRC) occurring under age 50-years should be screened to exclude Lynch syndrome. However, in current practice in East Anglia, tumour screening is initiated only after genetics referral, reserved for those with a strong pedigree. This study aimed to determine how many patients with young-onset CRC undergo tumour screening in hospitals in East Anglia. Method- A retrospective case notes review over 5-years in four hospitals was undertaken to determine what proportion of those with young-onset CRC underwent referral for tumour screening and to assess local practices in terms of patient counselling and management. Results- One hundred and twenty-two patients were included. There was an average yearly caseload of 6-9 p...

2011-01-01

180

Magnetic-field-induced phase transitions in Wigner molecules

Low-dose contrast protocol using the test bolus technique for 64-detector computed tomography coronary angiography

A theoretical analysis of formation and symmetry transformations is presented for Wigner molecules with N = 2,..., 20 electrons confined in quantum dots at high magnetic fields. Using the unrestricted Hartree-Fock method with the multicentre Gaussian basis, we have found that Wigner molecules with N {>=} 6 abruptly change their shape and symmetry with an associated jump in the first derivative of the ground-state energy, i.e. they undergo phase transitions. In particular, the phases of the Wigner molecules obtained just after emerging from the maximum-density droplet (MDD) phase possess a different symmetry from that formed at a high magnetic field. We show that the properties of the electron-electron interaction energy demonstrate very well both the breakdown of the MDD and the quasi-classical character of the Wigner molecule in the high magnetic field. Possible mechanisms of the MDD decay are discussed.

2003-06-25

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181

British Library Electronic Table of Contents (United Kingdom)

Purpose We evaluated low-contrast injection protocols for coronary computed tomography angiography (CTA) using a 64-detector scanner and the test bolus technique. Materials and methods We randomly assigned 60 patients undergoing coronary CTA to one of two contrast material (CM) injection protocols. For the lowcontrast dose protocol (Plow), the patients received injections of iohexol-350 [0.7 ml/kg body weight (BW)] during 9 s, and the test-bolus technique was used. Under the conventional protocol (Pconv), they received iohexol-350 (1.0 ml/kg BW) during 15 s, and bolus tracking was used. We compared the protocols for attenuation values in the ascending aorta and coronary arteries and for the amount of CM required. Results There was no significant difference in the mean CT attenuation of the...

2011-01-01

182

Ligand Tuning in Asymmetric Hydrovinylation of 1,3-Dienes. A Stereoselective Route to either Steroid-C20 (S) or -C20 (R) Derivatives

Interfacial ultrafine-grained structures on aluminum alloy 6061 joint and copper alloy 110 joint fabricated by magnetic pulse welding

1,3-Dienes derived from steroidal D-ring C17-ketones undergo Ni(II)-catalyzed hydrovinylation to give 1,2- or 1,4-addition of ethylene. Using finely tuned phosphoramidite ligands it is possible to synthesize either the C20 (R)- or the C20 (S)-derivatives without mutual contamination. The proportion of the 1,4-adduct, which is also formed stereoselectively, can be minimized by optimizing the reaction conditions. Since the two alkenes in the resultant dienes have differing steric demands for many potential reactions, and are ideally juxtaposed for further D-ring functionalization, these intermediates could be useful for the preparation of biologically important compounds such as vitamin D analogs and various antitumor steroidal glycosides.

2008-06-21

183

British Library Electronic Table of Contents (United Kingdom)

Magnetic pulse welding is a solid state impact welding process, similar to explosive welding, which produces metallurgical bond by oblique high-speed impact between two metal bodies. This violent impact removes the metal surface oxide layers and then joins the two atomic level clean metal surfaces together by the incidental compression pressure. The impact velocity is at 200?400?m/s and the being welded metal surface undergoes severe plastic deformation with strain rate in the order of 106?107?s?1. The ultrafine-grained structure was observed on the welded interface. This article studied two types of similar material lap joint interfaces and the base metals were aluminum alloy 6061 and copper alloy 110. Nano-indentation testing shows that the welded interfaces have significantly greater ha...

2010-01-01

184

Implications of the S-146 model for hideout and return in dented crevices

Idaho Explosives Detection System

As part of Steam Generators Owners Group Project S-146, ''Diffusion and Hideout in Crevices,'' experimental data were obtained on chloride salt hideout and return in a controlled-boiling INCON system containing three electrically heated, thermocouple instrumented tube-to-support-plate intersections. The support plate simulants had first been caused to undergo, in situ, denting-type corrosion to the extent that substantial tube deformation was observed. Then chloride hideout and return measurements were made, using sodium chloride as the impurity additive. Experimental results were fitted to an elementary model for the crevice and its associated transport processes. Details on the experimental work and a description of the data-fitting method are given in the final report, NP-2979, dated March 1983.

1985-03-01

185

Functionally defined substates within the human embryonic stem cell compartment.

The Idaho Explosives Detection System was developed at the Idaho National Laboratory (INL) to respond to threats imposed by delivery trucks potentially carrying explosives into military bases. A full-scale prototype system has been built and is currently undergoing testing. The system consists of two racks, one on each side of a subject vehicle. Each rack includes a neutron generator and an array of NaI detectors. The two neutron generators are pulsed and synchronized. A laptop computer controls the entire system. The control software is easily operable by minimally trained staff. The system was developed to detect explosives in a medium size truck within a 5-min measurement time. System performance was successfully demonstrated with explosives at the INL in June 2004 and at Andrews Air Force Base in July 2004.

2005-12-01

186

Human embryonic stem (ES) cells can undergo spontaneously differentiation in standard culture conditions, demonstrating that the undifferentiated state is relatively unstable. The heterogeneous expression of SSEA3 observed within human ES colonies, provides a means to examine undifferentiated stem cell substates. Through functional testing of single cells we have shown that undifferentiated ES cells can be segregated into functionally discrete subpopulations on the basis of SSEA3 expression: SSEA3(High), SSEA(Low) and SSEA3(Negative). Human ES subpopulations were found to be interconvertible, but they possess distinct properties when challenged to differentiate along the neural lineage. These data suggest that ES cells with pluripotent/self-renewal capacities can exhibit different responses to induction of differentiation. PMID:21763622

2011-05-11

187

FIRESET

Extremal behavior of a coupled continuous time random walk

FIRESET is a PC-based computer code which calculates current as a function of time for an RLC circuit containing up to fifteen series conductors which undergo rapid heating and subsequent explosion as a consequence of an electric current which passes through them. In its original form, the code was developed to model electrical waveforms measured when a large, typically 25.4 x 25.4 x 0.051-mm, aluminum foil was exploded using a capacitor bank with tens of kilojoules of stored energy. The code proved to be useful for this purpose, and it was recognized that it could also be used for modeling the electrical response of detonator bridgewires. In view of the increasing use of slapper detonators for DOD applications, we wish to make the latest version of the code, available to DOD laboratories and contractors for use in designing firing systems which employ slapper or exploding bridgewire detonators. This document provides instructions for the code.

1988-02-19

188

British Library Electronic Table of Contents (United Kingdom)

Coupled continuous time random walks (CTRWs) model normal and anomalous diffusion of random walkers by taking the sum of random jump lengths dependent on the random waiting times immediately preceding each jump. They are used to simulate diffusion-like processes in econophysics such as stock market fluctuations, where jumps represent financial market microstructure like log returns. In this and many other applications, the magnitude of the largest observations (e.g. a stock market crash) is of considerable importance in quantifying risk. We use a stochastic process called a coupled continuous time random maxima (CTRM) to determine the density governing the maximum jump length of a particle undergoing a CTRW. CTRM are similar to continuous time random walks but track maxima instead of sums....

2011-01-01

189

Evaluation of Capiox FX05 Oxygenator With an Integrated Arterial Filter on Trapping Gaseous Microemboli and Pressure Drop With Open and Closed Purge Line

British Library Electronic Table of Contents (United Kingdom)

Abstract Gaseous microemboli (GME) remain a challenge for cardiopulmonary bypass (CPB) because there is a positive correlation between microemboli exposure during CPB and postoperative neurological injury. Thus, minimizing the number of GME delivered to pediatric patients undergoing CPB procedures would lead to better clinical outcomes. In this study, we used a simulated CPB model to evaluate the effectiveness of capturing GME and the degree of membrane pressure drop for a new membrane oxygenator, Capiox Baby FX05 (Terumo Corporation, Tokyo, Japan), which has an integrated arterial filter with open and closed purge line. We used identical components in this study as our clinical CPB circuit. Three emboli detection and classification quantifier transducers were placed at prepump, preoxygena...

2010-01-01

190

Electron-phonon based local mode descriptions of displacive transformations

Effects of wildfires on environmental variability: a comparative analysis using different spectral indices, patch metrics and thematic resolutions

As a general approach to the problem of precursive behavior in alloys that undergo a displacive transformation, defect theories are becoming increasingly popular. However, the microscopic origin of the proposed defects is usually not considered. Yu and Anderson (1984) have argued that properties of strong-coupling superconductors, such as the A-15 compounds, imply a breakdown of Migdal's theorem (the adiabatic, or Born-Oppenheimer approximation for separation of electrons and phonons) in these systems. The electron-phonon coupling is so strong that it must be incorporated already in zeroth order. This is the basis for local phonon models, in which the electron-phonon coupling provides an effective double well potential for a localized group of atoms. The Yu-Anderson model and an analogous local Jahn-Teller model (Abell, 1983) are reviewed in connection with displacive transformations in strong-coupling alloys.

1986-01-01

191

British Library Electronic Table of Contents (United Kingdom)

Knowledge on environmental variability and how it is affected by disturbances is crucial for understanding patterns of biodiversity and determining adequate conservation strategies. The aim of this study is to assess environmental variability in patches undergoing post-fire vegetation recovery, identifying trends of change and their relevant drivers. We particularly evaluate: the value of three spectral indices derived from Landsat satellite data [Normalized Burn Ratio (NBR), Normalized Difference Vegetation Index (NDVI) and Wetness Component of the Tasseled Cap Transformation (TCW)] for describing secondary succession; the effectiveness of three metrics (diversity, evenness and richness) as indicators of patch variability; and how thematic resolution can affect the perception of environme...

2010-01-01

192

Economic assessment of combined cycle gas turbines in Australia Some effects of microeconomic reform and technological change

Drivers of Transfusion Decision Making and Quality of the Evidence in Orthopedic Surgery: A Systematic Review of the Literature

Australian electricity markets and natural gas markets are undergoing rapid reform. Choosing among electricity generation modes is a key issue. Such choices are affected by expectations about the future structure of these markets and future technologies, and how they affect costs and emissions. In the research reported in this paper, the MARKAL model of the Australian energy system is used to evaluate the competitive position of natural gas fired combined cycle gas turbines (CCGTs) in the energy sector as a whole. Competing in the sector are large-scale electricity generation technologies such as refurbished existing coal fired stations and advanced forms of coal fired generation. The modelling incorporates new data on electricity supply technologies and options.

2003-02-01

193

British Library Electronic Table of Contents (United Kingdom)

Reasons for variation in transfusion practice in orthopedic surgery are not well understood. This systematic review identified and appraised the quality of the literature in this area to assess the impact of factors associated with the use of allogeneic red blood cell (RBC) transfusion in orthopedic procedures. MEDLINE and EMBASE databases were searched for relevant English language publications. Articles containing a range of MeSH and text terms regarding ''blood transfusion,'' ''predictors,'' and ''multiple logistic regression'' were retrieved. Articles that focused on patients undergoing orthopedic procedures and that met prespecified inclusion criteria were appraised in terms of potential bias and the appropriateness of statistical approach. A total of 3641 citations were retrieved, an...

2011-01-01

194

Dosimetric considerations for patients with HIP prostheses undergoing pelvic irradiation. Report of the AAPM Radiation Therapy Committee Task Group 63

Diagnostic imaging in pregraduate integrated curricula; Radiologie in einem praegraduellen problembasiert-integrierten Medizincurriculum

This document is the report of a task group of the Radiation Therapy Committee of the AAPM and has been prepared primarily to advise hospital physicists involved in external beam treatment of patients with pelvic malignancies who have high atomic number (Z) hip prostheses. The purpose of the report is to make the radiation oncology community aware of the problems arising from the presence of these devices in the radiation beam, to quantify the dose perturbations they cause, and, finally, to provide recommendations for treatment planning and delivery. Some of the data and recommendations are also applicable to patients having implanted high-Z prosthetic devices such as pins, humeral head replacements. The scientific understanding and methodology of clinical dosimetry for these situations is still incomplete. This report is intended to reflect the current state of scientific understanding and technical methodology in clinical dosimetry for radiation oncology patients with high-Z hip ...

2003-06-01

195

Development of plasticity processing of magnesium alloys

Pregraduate medical curricula are currently undergoing a reform process that is moving away from a traditional discipline-related structure and towards problem-based integrated forms of teaching. Imaging sciences, with their inherently technical advances, are specifically influenced by the effects of paradigm shifts in medical education. The teaching of diagnostic radiology should be based on the definition of three core competencies: in vivo visualization of normal and abnormal morphology and function, diagnostic reasoning, and interventional treatment. On the basis of these goals, adequate teaching methods and e-learning tools should be implemented by focusing on case-based teaching. Teaching materials used in the fields of normal anatomy, pathology, and clinical diagnosis may help diagnostic radiology to play a central role in modern pregraduate curricula. (orig.)

2007-11-15

196

Detection of recurrence and the effect of transcatheter hepatic arterial embolization using lipiodol (Lp-TAE) assessed by the lipiodol accumulative pattern on CT

Recent developments on plastic forming technology of magnesium alloys are presented. Attempts have been undergoing with an aim at forming magnesium alloy parts at lower temperatures. It is believed that fine microstructure magnesium alloys usually have much higher plasticity at lower temperatures and even room temperatures. Extrusion is a method to form magnesium profile products and tube products, which is also one of the effective ways to make fine microstructure magnesium alloys. Superplasticity forming is another method to form high plasticity magnesium alloys. Hot forming of magnesium sheet parts is an important process to form magnesium products. Some developments related to above issues are discussed in the present paper. (orig.)

2003-07-01

197

Destructive spondyloarthropathy in hemodialysis patients. Report of four cases and prospective study

We evaluated the relation between the lipiodol accumulative pattern on CT 1 month after 1st Lp-TAE and the effect of Lp-TAE and recurrence of hepatocellular carcinoma (HCC) in 70 cases undergoing Lp-TAE twice. The lipiodol accumulative pattern on CT can be classified into four types (I: homogeneous, II: defect, III: inhomogeneous, IV: no or slight). In the type I, recurrence of the main tumor was 26.7%, daughter was 73.7%, suggesting a good effect of Lp-TAE. In the types II, III and IV, recurrence of the main tumor was seen in 66.7%, 83.3% and 83.3%, respectively, suggesting that the effect of Lp-TAE was worse according to the lipiodol accumulative pattern on CT. The lipiodol accumulative pattern on CT is useful for the detection of recurrence and assessment of the effect of Lp-TAE. (author).

1993-08-01

198

Design, synthesis and evaluation of 2-deoxy-2-iodovinyl-branched carbohydrates as potential brain imaging agents

A destructive spondyloarthropathy is reported in four patients undergoing maintenance hemodialysis for chronic renal disease. In a separate investigation a controlled, prospective radiographic study of the cervical spine revealed this spondyloarthropathy in 4 (15%) of 26 long-term dialysis patients. A single disk level was involved in three patients, and two disc levels were involved in one patient. This spondyloarthropathy correlated with the duration of dialysis but not with the radiographic evidence of renal osteodystrophy or severity of laboratory abnormalities associated with hyperparathyroidism. Three of these four patients also had discovertebral erosions or destruction involving the lumbar spine. Cervical spine flexion views revealed evidence of ligamentous laxity or instability in three (12%) dialysis patients, all with vertebral resorption and disc space narrowing. It is postulated that this instability may contribute to the development of cervical ...

1988-04-01

199

Design, synthesis and evaluation of 2-deoxy-2-iodovinyl-branched carbohydrates as potential brain imaging agents

Radioiodinated carbohydrates such as 2-deoxy-2-iodo-D-glucose and 3-deoxy-3-iodo-D-glucose undergo facile chemical or in vivo deiodination which precludes their use as radiotracers of glucose metabolism in tissues. To overcome the problems resulting from in vivo deiodination, we explored the concept of stabilizing radioiodide on a model carbohydrate, (E)-C-3-iodovinyl-D-allose (10) as an iodovinyl moiety. This agent did not exhibit brain specificity but showed low in vivo deiodination which demonstrated for the first time that radioiodide can be stabilized on a carbohydrate. The goal of this study was to develop a deoxy-branched carbohydrate with radioiodide stabilized as a vinyliodide with the objective of achieving high brain uptake. 10 refs., 1 fig., 1 tab.

2007-01-01

200

Design of a GaAs/Ge solar array for unmanned aerial vehicles

Radioiodinated carbohydrates such as 2-deoxy-2-iodo-D-glucose and 3-deoxy-3-iodo-D-glucose undergo facile chemical or in vivo deiodination which precludes their use as radiotracers of glucose metabolism in tissues. To overcome the problems resulting from in vivo deiodination, we explored the concept of stabilizing radioiodide on a model carbohydrate, (E)-C-3-iodovinyl-D-allose as an iodovinyl moiety. This agent did not exhibit brain specificity but showed low in vivo deiodination which demonstrated for the first time that radioiodide can be stabilized on a carbohydrate. The goal of this study was to develop a deoxy-branched carbohydrate with radioiodide stabilized as a vinyliodide with the objective of achieving high brain uptake. (author).

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201

Depression of calcium pump activity in renal cortex of vitamin D-deficient rats with secondary hyperparathyroidism

Unmanned Aerial Vehicles (UAV) are being proposed for many applications including surveillance, mapping and atmospheric studies. These applications require a lightweight, low speed, medium to long duration airplane. Due to the weight, speed, and altitude constraints imposed on such aircraft, solar array generated electric power is a viable alternative to air-breathing engines. Development of such aircraft is currently being funded under the Environmental Research Aircraft and Sensor Technology (ERAST) program. NASA Lewis Research Center (LeRC) is currently building a Solar Electric Airplane to demonstrate UAV technology. This aircraft utilizes high efficiency Applied Solar Energy Corporation (ASEC) GaAs/Ge space solar cells. The cells have been provided by the Air Force through the ManTech Office. Expected completion of the plane is early 1995, with the airplane currently undergoing flight testing using battery power.

1995-03-01

202

Depression of calcium pump activity in renal cortex of vitamin D-deficient rats with secondary hyperparathyroidism

To examine the hormonal regulation of the ATP-dependent Ca{sup 2+} pump in the kidneys, the ATP-dependent Ca{sup 2+} uptake by the basolateral membrane vesicles in the renal cortex was measured using radioactive calcium ({sup 45}Ca{sup 2+}) in rats with vitamin D deficiency or rats undergoing thyroparathyroidectomy. The V{sub max} of the Ca{sup 2+} pump activity was increased not only by administering calcitriol, but also by normalizing the serum calcium level in vitamin D-deficient rats. PTH suppressed the Ca{sup 2+} pump activity in normocalcemic vitamin D-deficient rats. Thyroparathyroidectomy did not affect the Ca{sup 2+} pump activity in the kidneys of normal rats. It was concluded that the ATP-dependent Ca{sup 2+} pump activity was depressed by secondary hyperparathyroidism in vitamin D-deficient rats. (author).

1990-01-01

203

Dense and diffuse gas in dynamically active clouds

To examine the hormonal regulation of the ATP-dependent Ca"2"+ pump in the kidneys, the ATP-dependent Ca"2"+ uptake by the basolateral membrane vesicles in the renal cortex was measured using radioactive calcium ("4"5Ca"2"+) in rats with vitamin D deficiency or rats undergoing thyroparathyroidectomy. The V_m_a_x of the Ca"2"+ pump activity was increased not only by administering calcitriol, but also by normalizing the serum calcium level in vitamin D-deficient rats. PTH suppressed the Ca"2"+ pump activity in normocalcemic vitamin D-deficient rats. Thyroparathyroidectomy did not affect the Ca"2"+ pump activity in the kidneys of normal rats. It was concluded that the ATP-dependent Ca"2"+ pump activity was depressed by secondary hyperparathyroidism in vitamin D-deficient rats. (author).

204

Comparison of Effectiveness and Safety of Ranolazine Versus Amiodarone for Preventing Atrial Fibrillation After Coronary Artery Bypass Grafting

We investigate the chemical and observational implications of repetitive transient dense core formation in molecular clouds. We allow a transient density fluctuation to form and disperse over a period of 1 Myr, tracing its chemical evolution. We then allow the same gas immediately to undergo further such formation and dispersion cycles. The chemistry of the dense gas in subsequent cycles is similar to that of the first, and a limit cycle is reached quickly (2 - 3 cycles). Enhancement of hydrocarbon abundances during a specific period of evolution is the strongest indicator of previous dynamical history. The molecular content of the diffuse background gas in the molecular cloud is expected to be strongly enhanced by the core formation and dispersion process. Such enhancement may remain for as long as 0.5 Myr. The frequency of repetitive core formation should strongly determine the level of background molecular enhancement. We also convolve the emission from a ...

2006-01-01

205

British Library Electronic Table of Contents (United Kingdom)

Atrial fibrillation (AF) is common after coronary artery bypass grafting (CABG) and increases the morbidity and cost. Amiodarone reduces AF after CABG. Ranolazine, an antianginal agent, also prolongs atrial refractoriness and inhibits after depolarizations and triggered activity; effects that could decrease AF after CABG. The present study compared amiodarone versus ranolazine for the prevention of AF after CABG. A retrospective cohort study of patients undergoing CABG at Aspirus Hospital from June 2008 to April 2010. The patients received either amiodarone (400 mg preoperatively followed by 200 mg twice daily for 10 to 14 days) or ranolazine (1,500 mg preoperatively followed by 1,000 mg twice daily for 10 to 14 days). The primary end point was any identified AF after CABG. A total of 393 ...

2011-01-01

206

Comparison of 25- and 23-gauge sutureless microincision vitrectomy surgery in the treatment of various vitreoretinal diseases

British Library Electronic Table of Contents (United Kingdom)

PurposeTo compare the effectiveness and safety of 25- and 23-gauge sutureless microincision vitrectomy surgery (MIVS) in the management of various vitreoretinal diseases.MethodsEighty-five consecutive patients undergoing sutureless vitrectomy during January to April 2008 were randomized to either 25- or 23-gauge MIVS. Data collected prospectively included best-corrected visual acuity (BCVA), operation time, postoperative visual recovery, postoperative anterior segment change, and complications.ResultsThe most common indications for MIVS were macular hole, macular pucker, vitreous haemorrhage, and diabetic traction retinal detachment. Mean operation times of the 25-gauge (n=38) and 23-gauge groups (n=47) were 33.68 and 34.47?min, respectively (P=0.942). Mean BCVA improved significantl...

2010-01-01

207

Chondrocytes and bone marrow-derived mesenchymal stem cells undergoing chondrogenesis in agarose hydrogels of solid and channelled architectures respond differentially to dynamic culture conditions

British Library Electronic Table of Contents (United Kingdom)

Abstract The objective of this study was to investigate how a combination of different scaffold architectures and rotational culture would influence the functional properties of thick cartilaginous tissues engineered using either chondrocytes or bone marrow-derived mesenchymal stem cells (BM-MSCs). Expanded porcine chondrocytes and BM-MSCs were suspended in 2% agarose and cast in custom-designed moulds to produce either regular solid or channelled construct cylinders. The study consisted of three seperate experimental arms. First, chondrocyte and BM-MSC constructs were cultured in free swelling conditions for 9 weeks. Second, constructs were subjected to rotational culture for a period of 3 weeks. Finally, BM-MSC-seeded constructs were subjected to delayed rotational culture, in which cons...

2011-01-01

208

Caburization kinetics of alloy-800 in liquid sodium at 550_0C

Association of area sociodemographic characteristics and capacity for treatment with disparities in colorectal cancer care and mortality

Preliminary observations on the isothermal carbon transfer in low-carbon Alloy-800 exposed in sodium with AISI-304 type of steel at 550_0 are reported. The alloy was found to undergo a carburization comparable or slightly lower than that observed for the AISI-304 stainless steel for carbon activities above 6 x 10 /sup -3/ at 550_0C, but was not found to decarburize below such a carbon activity value. In the examined range the chemical composition of the alloys does not affect the process out of the experimental uncertainty of measure. Conclusions concerning the effective diffusion for carbon in the alloy are formulated. Preliminary relationships were found for an empirical evaluation of the carburization of the Alloy-800 in sodium of known carbon activity.

209

British Library Electronic Table of Contents (United Kingdom)

AbstractBACKGROUND: Disparities in treatment and mortality for colorectal cancer (CRC) may reflect differences in access to specialized care or other characteristics of the area where an individual lives. METHODS: Surveillance, Epidemiology and End Results Program-Medicare data for seniors diagnosed with CRC were linked to area measures of the sociodemographic characteristics and the capacity of surgeons, medical oncologists, and radiation oncologists. Outcomes included receipt of stage-appropriate CRC care and mortality. RESULTS: After adjustment, blacks and Hispanics were less likely than whites to undergo surgery (odds ratio [OR] 0.57, 95% confidence interval (CI) 0.52-0.63 and OR 0.82, 95% CI 0.70-0.95, respectively). Individuals who lived in areas with the highest tertile of surgeon c...

2011-01-01

210

Aspects of selective oxidation and ammoxidation mechanisms over bismuth molybdate catalysts--2. Allyl alcohol as a probe for the allylic intermediate

Adsorption Kinetics of Surfactants at Fluid-Fluid Interfaces

Pulse reactor experiments were conducted on the reactions of unlabeled or deuterium- or oxygen-18-labeled allyl alcohols over molybdenum trioxide and various bismuth molybdates in the absence or presence of oxygen and ammonia. The allyl alcohol apparently adsorbed on oxidation sites to form acrolein via allyl molybdates, and on Broensted acid sites to form diallyl ether via an allyl carbonium ion. The bismuth enhanced ..cap alpha..-hydrogen abstraction, which was the rate-determining step in the oxidation. The product distributions provided evidence that the selective oxidation of propylene to acrolein proceeds via a m-allyl molybdate which collapses to an O o-allyl molybdate prior to the second hydrogen abstraction, and that the analogous N o-complex in ammoxidation undergoes two hydrogen abstractions to form acrylonitrile. Detailed reaction schemes are developed.

1980-05-01

211

A proof of concept study for a structure activity model for the toxicity of nanoparticles

We review a new theoretical approach to the kinetics of surfactant adsorption at fluid-fluid interfaces. It yields a more complete description of the kinetics both in the aqueous solution and at the interface, deriving all equations from a free-energy functional. It also provides a general method to calculate dynamic surface tensions. For non-ionic surfactants the results coincide with previous models. Common non-ionic surfactants are shown to undergo diffusion-limited adsorption, in agreement with experiments. Strong electrostatic interactions in salt-free ionic surfactant solutions are found to lead to kinetically limited adsorption. In this case the theory accounts for unusual experimental results which could not be understood using previous approaches. Added salt screens the electrostatic interactions and makes the ionic surfactant adsorption similar to the non-ionic case. The departure from the non-ionic behavior as the salt concentration is decreased is ...

1997-01-01

212

Environmental Research Database

ObjectivesThe development of novel formulations of nanoparticles in the nanotechnology industry and their increasing importance and use in industry means there is certainty of human environmental exposures in both the workplace and the general environment. The pulmonary route of exposure to airborne nanoparticles is a major one, as nanoparticles are handled in industry, escape from workplaces and products containing nanoparticles undergo attrition in the environment. There is a substantial problem for ris [continued...]DescriptionNanoparticles are extremely small particles, each individual particlel being less than one ten millionth of a metre in size. We are exposed to nanoparticles in busy streets as they are present in traffic exhaust produced from combustion of fuel and such nanoparticles are considered to be important in causing the harmful effects associated with exposure to air pollution. There are other situations where nanoparticles are found in the air, ...

2009-01-28

213

A novel accelerated oxidative stability screening method for pharmaceutical solids

British Library Electronic Table of Contents (United Kingdom)

Abstract Despite the fact that oxidation is the second most frequent degradation pathway for pharmaceuticals, means of evaluating the oxidative stability of pharmaceutical solids, especially effective stress testing, are still lacking. This paper describes a novel experimental method for peroxide-mediated oxidative stress testing on pharmaceutical solids. The method utilizes urea-hydrogen peroxide, a molecular complex that undergoes solid-state decomposition and releases hydrogen peroxide vapor at elevated temperatures (e.g., 30C), as a source of peroxide. The experimental setting for this method is simple, convenient, and can be operated routinely in most laboratories. The fundamental parameter of the system, that is, hydrogen peroxide vapor pressure, was determined using a modified spect...

2011-01-01

214

Mean glandular doses for women undergoing mammographic breast screening in Oyo state, Nigeria

Mean glandular doses for women undergoing mammographic breast screening in Oyo state, Nigeria

In this work, thermoluminescent dosimeters have been used to measure entrance surface doses (ESDs) of patients undergoing mammographic screening at the University College Hospital, Ibadan, Oyo state. The mean glandular doses (MGDs) were also calculated using the measured ESDs. The results showed that the ESDs ranged from 0.26 mGy to 21.26 mGy for the mediolateral oblique (MLO) views and 0.08 mGy to 5.36 mGy for the craniocaudal (CC) views. The calculated MGD ranged from 0.07 mGy to 3.57 mGy for the MLO views and 0.02 mGy to 0.98 mGy for the CC views. The possible reasons for the large variations in the individual ESD values and MGD values for both views are discussed using patients' data, equipment specific data and the technical parameters used for the examinations. Comparison showed that the mean ESD values and MGD values reported in this work are below published values. The mean of the calculated MGD values is also found to be lower than the recommended ...

2009-11-15

215

Decay of "1"7"7T_a composite nucleus. Comparison of excitation functions for the reaction residues occurring in "1"2C + "1"6"5H_0 and "1"4N + "1"6"3D_y reactions

In this work, thermoluminescent dosimeters have been used to measure entrance surface doses (ESDs) of patients undergoing mammographic screening at the University College Hospital, Ibadan, Oyo state. The mean glandular doses (MGDs) were also calculated using the measured ESDs. The results showed that the ESDs ranged from 0.26 mGy to 21.26 mGy for the mediolateral oblique (MLO) views and 0.08 mGy to 5.36 mGy for the craniocaudal (CC) views. The calculated MGD ranged from 0.07 mGy to 3.57 mGy for the MLO views and 0.02 mGy to 0.98 mGy for the CC views. The possible reasons for the large variations in the individual ESD values and MGD values for both views are discussed using patients' data, equipment specific data and the technical parameters used for the examinations. Comparison showed that the mean ESD values and MGD values reported in this work are below published values. The mean of the calculated MGD values is also found to be lower than the recommended guidance ...

2009-11-01

216

Characterization of monocyte differentiation-inducing (MDI) factors derived from human fetal membrane chorion cells undergoing apoptosis after influenza virus infection.

The experimental has been performed with a view to studying complete and incomplete fusion in "1"4N + "1"6"3D_y system below 7 MeV/nucleon. The excitation functions for several reactions have been measured using the activation technique and compared with the theoretical predictions based on statistical models. The codes ALICE-91 and CASCADE used earlier for the analysis of excitation functions in case of "1"2C + "1"6"5H_0 system have been used here also with the same set of input parameters. It has been observed that the theoretical calculations do not match with the experimental excitation functions well but the overall shape of the excitation function is reproduced satisfactorily. The composite nucleus ("1"7"7T_a) formed in this ("1"4N + "1"6"3D_y) case is the same as the one formed in "1"2C + "1"6"5H_0 system studied earlier. Measured excitation functions for the same decay channels in the two cases (i.e. "1"2C + "1"6"5H_0 and "1"4N + "1"6"3D_y) have been compared. A comparison of ...

2002-10-01

217

Zinc air battery development for electric vehicles. Final report

Influenza virus infection during pregnancy has been implicated as one of cause of premature delivery, abortion and stillbirth. We have reported that cultured human fetal membrane chorion cells undergoing apoptosis by influenza virus infection secrete unidentified heat-stable monocyte differentiation-inducing (MDI) factors. In this study, cellular, biological and immunochemical characteristics of MDI factors were investigated using human monocytic leukemia THP-1 cells by nitroblue tetrazolium reduction and cell adhesion assays. The treatment of THP-1 cells with culture supernatants from the influenza virus-infected chorion cells induced the nitroblue tetrazolium reduction ability, which was inhibited by the addition of superoxide dismutase and diphenyleneiodonium chloride, an inhibitor for reduced nicotinamide adenine dinucleotide phosphate oxidase. The phenomenon was also observed in human peripheral blood monocytes and histiocytic leukemia U937 cells, but not in ...

2006-06-06

218

Zinc air battery development for electric vehicles

This report summarizes the results of research conducted during the sixteen month continuation of a program to develop rechargeable zinc-air batteries for electric vehicles. The zinc-air technology under development incorporates a metal foam substrate for the zinc electrode, with flow of electrolyte through the foam during battery operation. In this ``soluble`` zinc electrode the zincate discharge product dissolves completely in the electrolyte stream. Cycle testing at Lawrence Berkeley Laboratory, where the electrode was invented, and at MATSI showed that this approach avoids the zinc electrode shape change phenomenon. Further, electrolyte flow has been shown to be necessary to achieve significant cycle life (> 25 cycles) in this open system. Without it, water loss through the oxygen electrode results in high-resistance failure of the cell. The Phase I program, which focused entirely on the zinc electrode, elucidated the conditions necessary to increase electrode capacity from 75 ...

1991-07-01

219

Viscoplasticity of elastomeric materials: experimental facts and constitutive modelling

This report summarizes the results of research conducted during the sixteen month continuation of a program to develop rechargeable zinc-air batteries for electric vehicles. The zinc-air technology under development incorporates a metal foam substrate for the zinc electrode, with flow of electrolyte through the foam during battery operation. In this soluble'' zinc electrode the zincate discharge product dissolves completely in the electrolyte stream. Cycle testing at Lawrence Berkeley Laboratory, where the electrode was invented, and at MATSI showed that this approach avoids the zinc electrode shape change phenomenon. Further, electrolyte flow has been shown to be necessary to achieve significant cycle life (> 25 cycles) in this open system. Without it, water loss through the oxygen electrode results in high-resistance failure of the cell. The Phase I program, which focused entirely on the zinc electrode, elucidated the conditions necessary to increase electrode ...

1991-07-01

220

Virtual colonoscopy (CT colonography) in the identification of colorectal cancer. A prospective study in symptomatic patients

A characteristic of filled elastomers is their ability to undergo very large deformations without damaging their internal structure. The material behaviour is mainly elastic, however, elastomers show hysteresis effects leading to damping properties, which are quite important as regards their applications in various fields of mechanical engineering.A series of experiments (tension, torsion and combinations of both) was carried out on cylindrical bars made of a carbon-black filled rubber mixture. In addition to a pronounced nonlinear rate-dependence, relaxation and viscosity properties are observed as being influenced by the process histories.The behaviour of elastomeric materials is modelled on the basis of a free energy function and evolution equations for additional internal variables. Incorporating or disregarding the very small rate-independent hysteresis, the constitutive modelling may be classified under viscoplasticity or viscoelasticity. The constitutive ...

2001-03-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

221

Variability and spectral modeling of the hard X-ray emission of GX 339-4 in a bright low/hard state

Aim of this study was to evaluate the sensitivity of virtual colonoscopy (CT colonography) in the identification of colorectal cancer and to define the limitations and the advantages of this imaging modality, as well as indications to the examination. It was examined prospectively 62 symptomatic patients aged 36 to 82 years (28 women and 34 men). All patients underwent both conventional and virtual colonoscopy on the same day; the conventional examination allowed exploration of the entire colon. Conventional colonoscopy identified 89 lesions 3-50 mm in diameter, namely 84 benign and 5 malignant lesions. No lesions were identified in 12 patients. CT colonography identified 52 of the 89 lesions, with 57.1% diagnostic accuracy. They were 11 false positives (82.5% positive predictive value and 52.2% specificity) and 37 false negatives (24.5% negative predictive value and 58.4% sensitivity). Sensitivity was significantly higher (85.7%) for polyps #>=# 1 cm. Virtual colonoscopy is an ...

2000-06-01

222

V/sub 2/O/sub 5/-P/sub 2/O/sub 5/ glasses as cathode for lithium secondary battery

We study the high-energy emission of the Galactic black hole candidate GX 339-4 using INTEGRAL/SPI and simultaneous RXTE/PCA data. By the end of January 2007, when it reached its peak luminosity in hard X-rays, the source was in a bright hard state. The SPI data from this period show a good signal to noise ratio, allowing a detailed study of the spectral energy distribution up to several hundred keV. As a main result, we report on the detection of a variable hard spectral feature (>150 keV) which represents a significant excess with respect to the cutoff power law shape of the spectrum. The SPI data suggest that the intensity of this feature is positively correlated with the 25 - 50 keV luminosity of the source and the associated variability time scale is shorter than 7 hours. The simultaneous PCA data, however, show no significant change in the spectral shape, indicating that the source is not undergoing a canonical state transition. We analyzed the broad band ...

2010-01-01

223

Uptake and utilization of nutrients by developing kernels of Zea mays L

During past two decades, the importance of rechargeable lithium cells has been emphasized and a large variety of materials has been discovered and evaluated for use as reversible cathodes and electrolytes. Materials that undergo intercalation or topochemical reactions with lithium have been investigated as candidates for cathodes in nonaqueous secondary lithium cells (1). Recent interest in researching cathode active materials has mainly focussed on crystalline transition metal chalcogenides. On the other hand, electrochemical behaviors of several amorphous materials have been reported, for example MoS/sub 2/,MoS/sub 3/,V/sub 2/S/sub 5/ (2) and LiV/sub 3/O/sub 8/ (3). However, no successful cycling behavior has been obtained except for MoS/sub 2/ in the amorphous state. This paper reports electrochemical data on rechargeable vanadate glasses in the system V/sub 2/O/sub 5/-P/sub 2/O/sub 5/.

1985-02-01

224

Uncovering camouflage: amygdala activation predicts long-term memory of induced perceptual insight.

The mechanisms involved in amino acid and sugar uptake by developing maize kernels were investigated. In the pedicel region of maize kernel, the site of nutrient unloading from phloem terminals, amino acids are accumulated in considerable amounts and undergo significant interconversion. A wide spectrum of enzymatic activities involved in the metabolism of amino acids is observed in these tissues. Subsequently, amino acids are taken up by the endosperm tissue in processes which require energy and the presence of carrier proteins. Conversely, no evidence was found that energy and carriers are involved in sugar uptake. This process of sugar uptake is not inhibited by metabolic inhibitors and shows nonsaturable kinetics, but the uptake is pH-dependent. L-glucose is taken up at a significantly reduced rate in comparison to D-glucose uptake. Based on analysis of radioactivity distribution among sugar fractions after incubations of kernels with radiolabeled D-glucose, it ...

1987-01-01

225

Title of paper: the induction of P-53 independent programmed cell death (apoptosis) with ionizing radiation and 5-fluorouracil (5-FU) in the HT-29 human colon carcinoma cell line

What brain mechanisms underlie learning of new knowledge from single events? We studied encoding in long-term memory of a unique type of one-shot experience, induced perceptual insight. While undergoing an fMRI brain scan, participants viewed degraded images of real-world pictures where the underlying objects were hard to recognize ("camouflage"), followed by brief exposures to the original images ("solution"), which led to induced insight ("Aha!"). A week later, the participants' memory was tested; a solution image was classified as "remembered" if detailed perceptual knowledge was elicited from the camouflage image alone. During encoding, subsequently remembered images were associated with higher activity in midlevel visual cortex and medial frontal cortex, but most pronouncedly, in the amygdala, whose activity could be used to predict which solutions will remain in long-term memory. Our findings extend the known roles of amygdala in memory to include promotion ...

2011-03-10

226

The tunneling universe in scalar-tensor theory with matter

Purpose/Objective: The role of programmed cell death (apoptosis) as a cellular response to cancer therapy such as radiation or chemotherapy is the subject of much study, and manipulation of the apoptotic response in tumor cells may be valuable in the treatment of a variety of cancers. Both p53 dependent and independent apoptotic pathways have been identified; p53 is mutated in at least 50 % of human cancers and a majority of radiation resistant tumors contain p53 mutations. This study is designed to examine the induction of programmed cell death in a human colon carcinoma cell line that possesses two mutated p53 alleles. Ionizing radiation alone, or in combination with the chemotherapeutic drug 5-fluorouracil (5-FU), were used to elicit the apoptotic response. This study will focus on whether these treatments can induce a significant apoptotic response in cells that have mutated p53 alleles. Materials and Methods: HT-29 cells were assessed for clonogenic survival after being plated at ...

1996-09-01

227

The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding

In this paper, the wavefunction of the universe with a tunneling boundary condition is considered in the context of the Brans-Dicke-type scalar-tensor theory with matter. The matter may be interpreted as a D-particle (or D0-brane) in string theory when the Brans-Dicke parameter {omega} is -1. We study two simple examples. The first example, the {gamma}=0 (matter) case, has a scale factor duality even if the low energy string action is coupled to matter. The universe undergoes quantum transition from super-inflationary (pre-big-bang) to deflationary (post-big-bang) phase. We calculate the transition rate by solving the Wheeler-DeWitt equation and find that it is non-vanishing. The two phases are disconnected classically. The second example is the {gamma}=1/3(radiation) case. With the help of earlier work this matter can be identified with a D0-brane in string theory. In this case, due to the absence of the scale factor duality and the complicated relations between ...

2007-10-21

228

The role of succinylcholine in the prevention of the obturator nerve reflex during transurethral resection of bladder tumors

Myostatin is a member of the transforming growth factor-{beta} (TGF-{beta}) family and a strong negative regulator of muscle growth. Here, we present the crystal structure of myostatin in complex with the antagonist follistatin 288 (Fst288). We find that the prehelix region of myostatin very closely resembles that of TGF-{beta} class members and that this region alone can be swapped into activin A to confer signalling through the non-canonical type I receptor Alk5. Furthermore, the N-terminal domain of Fst288 undergoes conformational rearrangements to bind myostatin and likely acts as a site of specificity for the antagonist. In addition, a unique continuous electropositive surface is created when myostatin binds Fst288, which significantly increases the affinity for heparin. This translates into stronger interactions with the cell surface and enhanced myostatin degradation in the presence of either Fst288 or Fst315. Overall, we have identified several ...

2009-09-29

229

The influence of the nature of the metal on the performance of cerium oxide supported catalysts in the partial oxidation of ethanol

Objective was to present our 8 year experience in the prevention of the obturator nerve reflex during transurethral resection of bladder tumors. This study was performed in Ataturk University Hospital between 1999 and 2007. We retrospectively reviewed the records of 89 patients with inferolateral bladder tumors, who underwent transurethral resection under epidural or general anesthesia and requested obturator nerve reflex inhibition. Epidural anesthesia was administered to 57 patients, while the remaining 32 patients underwent general anesthesia via mask; and succinylcholine was administered prior to resection. Of the 57 patients received epidural anesthesia, 18 were diagnosed as inferolateral bladder tumors during endoscopy and had to undergo general anesthesia. Obturator nerve block was attempted preoperatively in 39 patients. However, a nerve identification failure, hematoma and 4 obturator nerve reflex events, despite the block, were observed and these patients ...

230

The Outermost Ejecta of Type Ia Supernovae

This work studied the effect of the nature of the metal on the performance of Co/CeO{sub 2}, Pd/CeO{sub 2} and Pt/CeO{sub 2} catalysts in the partial oxidation of ethanol. Infrared spectroscopy of adsorbed ethanol and temperature programmed desorption of ethanol were performed in order to establish the reaction mechanism. Catalytic experiments revealed that the product distribution is strongly affected by the nature of the metal. Acetaldehyde was practically the only product formed on a Co/CeO{sub 2} catalyst while methane was also produced on Pt/CeO{sub 2} and Pd/CeO{sub 2} catalysts. These results were explained through a reaction mechanism proposed by the characterization techniques. Co/CeO{sub 2} and Pt/CeO{sub 2} catalysts show mainly ethoxy species at room temperature whereas acetate species is mainly formed on the Pd/CeO{sub 2} catalyst. The ethoxy species can undergo further dehydrogenation and desorb as acetaldehyde. This effect is more significant with ...

2005-12-01

231

Systematic implicit solvent coarse-graining of bilayer membranes: lipid and phase transferability of the force field

The properties of the highest velocity ejecta of normal Type Ia supernovae (SNe Ia) are studied via models of very early optical spectra of 6 SNe. At epochs earlier than 1 week before maximum, SNe with a rapidly evolving Si II 6355 line velocity (HVG) have a larger photospheric velocity than SNe with a slowly evolving Si II 6355 line velocity (LVG). Since the two groups have comparable luminosities, the temperature at the photosphere is higher in LVG SNe. This explains the different overall spectral appearance of HVG and LVG SNe. However, the variation of the Ca II and Si II absorptions at the highest velocities (v >~ 20,000 km/s) suggests that additional factors, such as asphericity or different abundances in the progenitor white dwarf, affect the outermost layers. The C II 6578 line is marginally detected in 3 LVG SNe, suggesting that LVG undergo less intense burning. The carbon mass fraction is small, only less than 0.01 near the photosphere, so that he mass ...

2007-01-01

232

Sucrose transport into stalk tissue of sugarcane

We study the lipid and phase transferability of our recently developed systematically coarse-grained solvent-free membrane model. The force field was explicitly parameterized to describe a fluid 1-palmitoyl-2-oleoyl-phosphatidylcholine (POPC) bilayer at 310 K with correct structure and area per lipid, while gaining at least three orders of magnitude in computational efficiency (see Wang and Deserno 2010 J. Phys. Chem. B 114 11207-20). Here, we show that exchanging CG tails, without any subsequent re-parameterization, creates reliable models of 1,2-dioleoylphosphatidylcholine (DOPC) and 1,2-dipalmitoylphosphatidylcholine (DPPC) lipids in terms of structure and area per lipid. Furthermore, all CG lipids undergo a liquid-gel transition upon cooling, with characteristics like those observed in experiments and all-atom simulations during phase transformation. These studies suggest a promising transferability of our force field parameters to different lipid species and ...

2010-09-01

233

Structure and magnetic properties of RE_4CoCd and RE_4RhCd (RE = Tb, Dy, Ho)

The productivity of higher plants is, in part, dependent on transport of photosynthate from source to sink (in sugarcane, stalk) and upon its assimilation in cells of the sink tissue. In sugarcane, sucrose has been reported to undergo hydrolysis in the apoplast before uptake into the storage parenchyma, whereas recently, sucrose was reported to be taken up intact. This work was based on lack of randomization of ({sup 14}C)fructosyl sucrose accumulated after feeding tissue slices with this sugar. In this report, we present evidence from slices of stalk tissue that sucrose is taken up intact via a carrier-mediated, energy-dependent process. The evidence includes: (1) uptake of fluorosucrose, an analog of sucrose not subject to hydrolysis by invertase; (2) little or no randomization of ({sup 14}C) fructosyl sucrose taken up; (3) the presence of a saturable as well as a linear component of sucrose uptake; and (4) inhibition of both the saturable and linear components ...

1990-05-01

234

Ship of challenges: Braced for perfect storms, icebergs and oilfield hazards

New rare earth metal rich cadmium compounds RE_4CoCd and RE_4RhCd (RE = Tb, Dy, Ho) were prepared by high-frequency melting of the elements in sealed tantalum tubes. The samples were studied by x-ray powder and single-crystal diffraction. All the compounds crystallize with Gd_4RhIn-type structure, with space group F4-bar3m. The structures are built up from rigid three-dimensional networks of condensed, cobalt (rhodium) centred trigonal RE_6 prisms. The voids left by these networks are filled by Cd_4 cluster units and the coordination number 14 polyhedra of the RE1 atoms. The terbium and dysprosium compounds in both series undergo antiferromagnetic ordering, whereas the holmium compounds exhibit ferromagnetic ordering. The magnetic ordering in these compounds is characterized by broad peaks around the transition temperatures. The results of detailed crystallographic investigations and preliminary magnetic and specific heat studies are presented and discussed in this ...

2007-02-21

235

Self-Interacting Dark Matter Halos and the Gravothermal Catastrophe

More details about the construction of the Terra Nova floating production, storage and offloading (FPSO) vessel are provided. The vessel was built in the Daewoo shipyard in South Korea, and is now undergoing final fitting at Bull Arm, near St. John's, Newfoundland. When complete, the vessel will operate 350 km offshore, southeast of St. John's. It is 291 metres long and 45.5 metres wide and has a capacity of 960,000 barrels of oil. Although the FPSO will hold less than half of the last giant supertanker which sailed for Irving Oil, it has a crew of 81, four times the size of the supertanker, reflecting the technical uniqueness of the vessel and the intense pre-occupation with safety associated with the combination of winds, ice, waves, and shallow water around the Grand Banks. Also described is the alliance system of partnership between the oil companies and the main contractors. The deal stipulates that if the project ran over its budget, the oil ...

2001-08-06

236

Selective absorption of ultraviolet laser energy by human atherosclerotic plaque treated with tetracycline

We study the evolution of an isolated, spherical halo of self-interacting dark matter (SIDM) in the gravothermal fluid formalism. We show that the thermal relaxation time, $t_r$, of a SIDM halo with a central density and velocity dispersion of a typical dwarf galaxy is significantly shorter than its age. We find a self-similar solution for the evolution of a SIDM halo in the limit where the mean free path between collisions, $\\lambda$, is everywhere longer than the gravitational scale height, $H$. Typical halos formed in this long mean free path regime relax to a quasistationary gravothermal density profile characterized by a nearly homogeneous core and a power-law halo where $\\rho \\propto r^{-2.19}$. We solve the more general time-dependent problem and show that the contracting core evolves to sufficiently high density that $\\lambda$ inevitably becomes smaller than $H$ in the innermost region. The core undergoes secular collapse to a singular state (the ...

2002-01-01

237

Secondary cell with orthorhombic alkali metal/manganese oxide phase active cathode material

Tetracycline is an antibiotic that absorbs ultraviolet light at 355 nm and preferentially binds to atherosclerotic plaque both in vitro and in vivo. Tetracycline-treated human cadaveric aorta was compared with untreated aorta using several techniques: absorptive spectrophotometry; and tissue uptake of radiolabeled tetracycline, which showed 4-fold greater uptake by atheroma than by normal vessel. In addition, intravenous tetracycline administered to patients undergoing vascular surgery demonstrated characteristic fluorescence in surgically excised diseased arteries. Because of tetracycline's unique properties, the authors exposed tetracycline-treated and untreated aorta to ultraviolet laser radiation at a wavelength of 355 nm. They found enhanced ablation of tetracycline-treated atheroma compared with untreated atheroma. The plaque ablation caused by ultraviolet laser radiation was twice as extensive in tetracycline-treated vs nontreated plaque. This study ...

1985-05-01

238

Radiolytic stabilization of poly(methyl methacrylate) using commercial additives; Estabilizacao radiolitica do poli(metacrilato de metila) usando aditivos comerciais

An alkali metal manganese oxide secondary cell is disclosed which can provide a high rate of discharge, good cycling capabilities, good stability of the cathode material, high specific energy (energy per unit of weight) and high energy density (energy per unit volume). The active material in the anode is an alkali metal and the active material in the cathode comprises an orthorhombic alkali metal manganese oxide which undergoes intercalation and deintercalation without a change in phase, resulting in a substantially linear change in voltage with change in the state of charge of the cell. The active material in the cathode is an orthorhombic structure having the formula M.sub.x Z.sub.y Mn.sub.(1-y) O.sub.2, where M is an alkali metal; Z is a metal capable of substituting for manganese in the orthorhombic structure such as iron, cobalt or titanium; x ranges from about 0.2 in the fully charged state to about 0.75 in the fully discharged state, and y ranges from 0 to ...

1996-01-01

239

Radioisotope space power generator annual report for the period October 1, 1976-September 30, 1978

Poly(methyl methacrylate), PMMA, Acrigel, a Brazilian polymer, is used in the manufacture of medical supplies sterelizable by ionizing radiation. However, when PMMA is gamma-irradiated it undergoes main chain scissions, which promote molecular degradation causing reduction in its mechanical properties. Therefore, radiolytic of PMMA is important for it to become commercially radiosterizable. In this work some commercial additives, originally used in photo-and thermo-oxidate stabilization of polymers, were tested. Only two additives, type HALS (Hindered Amine Light Stabilizer), denoted Scavenger, showed a good protective quality. The investigation of radiation-induced main scissions was carried out by viscosimetric method. The most effective additive, added to the polymer system at 0.3 w/w%, promotes a great molecular radioprotection of 93%. That means a reduction of G-value (scissions/100 eV) from 0.611 to 0.053. In addition, the glassy transition temperature (T{sub ...

2000-04-01

240

Radioadapted chicken embryo cells: challenge specificity and alterations in higher-order DNA structure

Techniques for fabricating P-type (Cu,Ag)/sub 2/Se with mesh-type bonds have been developed and are being evaluated for long-term use. In addition, methods for reducing vapor suppression by the use of coatings and/or baffling continue to show gains. The N-type alloy Gd/sub 2/Se/sub 3/ has been shown to be thermally unstable. It undergoes a sluggish cubic-to-orthorhombic phase change below 1000/sup 0/C, with an accompanying degradation in mechanical and thermoelectric properties. Fabrication studies conducted with the (Bi,Sb)/sub 2/(Se,Te)/sub 3/ alloys showed these materials to be sensitive to oxygen contamination if reproducible properties are to be obtained. Preparation of powdered material by explosive techniques was investigated. This technique appears to be useful in preparing homogeneous -325 mesh material, but it does not yield a useful amount of submicron-size powder.

1980-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

241

Proton spin lattice relaxation studies in lithium ammonium sulfate LiNH_4SO_4

Radioadapted chicken embryo cells (X-irradiation in ovo with 10 cGy at the 14th day of development with priming periods of 24 h) were treated in vitro by challenge doses of 14 different DNA- and/or chromatin-interactive agents, including X-rays. A decrease in the cellular damage, as measured by scheduled DNA synthesis, was only observed with X-irradiation. Sedimentation of nucleoids as well as viscosity of alkaline lysates from ethidium bromide (0.35-400 {mu}g/ml)-, vovobiocin (125-1800 {mu}g/ml)-, and hyperthermia (30 min at 43 and 45 )-treated cells suggest a higher tendency of radioadapted cells to undergo positive DNA supercoiling. When DNA from adapted and non-adapted chicken embryo cells was used as substrate, neither its digestion by DNase I nor the inhibition of DNase I activity by various DNA-interactive agents was changed in primed cells. From the previous investigations as well as from the present results it is concluded that an increase of tightening of ...

1996-03-01

242

Production, transport and injection of a cold non-magnetized electron beam for the recirculating linac

Lithium ammonium sulfate (LAS) undergoes a phase transition at Tsub(c1) = 459.5deg K from a paraelectric phase (phase 1) to a ferroelectric phase (phase II) and again at Tsub(c2) = 283deg K to a polar ferroelastic phase (phase III). Proton spin lattice relaxation investigations in the temperature range 480-77deg K at 10 MHz show discontinuous changes in Tsub(1) at the transition temperatures, indicating first order phase transitions. The absence of the slow motion region (#omega#sub(not)tausub(not)>>1) shows that the ammonium ions are reorienting fast enough to keep the resonance absorption line narrow down to liquid nitrogen temperatures. The possibility of a second minimum and a low activation energy, Esub(a) = 2.659 kcal/mole, in phase III suggest the possibility of tunnelling of the protons at low temperatures. The nature of the transitions have been discussed in the light of the available literature. The unusually high activation energy, Esub(a) = 17.845 ...

1978-12-31

243

Phloem loading: an integrated approach

A new foilless diode with a non-magnetically immersed cathode was recently designed and built for the Sandia Recirculating Linear Accelerator (RLA). Because there is also no radial component of electric field at the cathode, the electron beam starts almost parallel and is matched to a solenoidal transport system with minimum increase in divergence and radius. The electrode emission surface is specified by an area covered with felt which undergoes explosive electron emission at low electrical field stresses (60 kV/cm). The 1.7 MV, 4.8-kA produced beam is transported 1.5 meters to the injection region of the racetrack via a system of solenoids and focusing coils. The maximum transverse velocity component at injection point (1.5 m downstream from the cathode surface) is #beta# perpendicular = 0.03 and the radius r = 2.8 cm which give a quite small beam emittance #epsilon# = 0.08 rad-cm. Three- dimensional numerical simulations suggest that tangential injection into ...

1989-06-01

244

Oxide growth on aluminium alloys in the presence of ammonium fluoborate

This study focuses on the regulation of sucrose transport across the plasmalemma. Initially, we re-examined the use of leaf discs to study the kinetics of phloem loading using Allium cepa leaves. All tissues exhibited the same linear plus saturable profile as Beta vulgaris, except fructose uptake into the inner parenchyma and bundle-sheath cells; in this case the response was linear. These results indicate that all tissues of the leaf retrieve exogenous sucrose such that kinetics from leaf discs cannot be taken to represent phloem loading per se. We continued our study by investigating the influence of internal sugars on sugar transport across the plasmalemma. We found that if internal sugars were manipulated by heat-girdling techniques or DCMU treatment there was no appreciable change in sucrose influx. However, longer term heat-girdling decreased sucrose uptake. These data indicate that carbohydrate partitioning among the chloroplast, cytosol, and vacuole modulates cytosolic sugar ...

1986-01-01

245

Optimization of maintenance programme at Daya Bay Nuclear Power Station based on RCM analysis results

The aim of this study as to determine the mechanisms involved in using ammonium fluoborate as a reducing atmosphere when preheating a high magnesium content aluminium alloy. Rutherford Backscattering (RBS) has been the major technique used in the analysis of samples, it revealed significant reduction in both the diffusion of magnesium to the surface and the calculated oxide thickness in the presence of NH{sub 4}BF{sub 4}. At temperatures above 500 deg C in air, SEM images revealed depressions and voids due to incipient melting at various stages, around the grain boundaries. Grain boundaries effectively acted as pipes aiding the diffusion of magnesium to the surface. These results have been verified through compositional analysis with both RBS and auger electron spectroscopy (AES). Results from NH{sub 4}BF{sub 4} atmosphere preheat conditions showed significant improvements. It was verified experimentally that above 500 deg C , AA5182 alloys undergo incipient ...

1996-12-31

246

Numerical testing of hypotheses for the recent thinning and acceleration of Greenland outlet glaciers

This paper begins with an introduction to Guangdong Daya Bay Nuclear Power Station (GNPS) and gives a simple introduction to the operations and maintenance documentation system at GNPS. It then will review the maintenance program guidelines base and the associated problems prior to the application of reliability centered maintenance (RCM). How RCM was implemented at GNPS, how the results of RCM analysis were used to optimize the maintenance program and test program, and what is the interface between RCM and the existing maintenance program will be shown. Next, it will show the successful implementation of RCM at GNPS resulted in the following changes: A new understanding of equipment failure challenges operations and maintenance beliefs, maintenance concepts undergo a large change, maintenance program and periodic testing program are continuously modified and optimized, new on-condition maintenance technologies are introduced, non-productive scheduled overhauls are ...

2003-12-01

247

Environmental Research Database

ObjectivesThe overall scientific aim of this project is, through development of an appropriate numerical modelling tool, to identify and investigate the mechanisms that control the current observed rapid thinning and acceleration of Greenland outlet glaciers and to investigate their likely future behaviour in the context of climate warming. This aim is addressed through the four major specific objectives below. These objectives build on each and therefore the order of priority is driven by the order in wh [continued...]DescriptionCurrently, the Greenland ice sheet is undergoing rapid changes in the coastal regions which have been attributed to a general warming trend to the regions climate over the last decade. Several of the narrow and fast flowing outlet glaciers that drain the ice sheet into the sea are observed to have accelerated their flow and thinned. For instance, Jakobshavn Isbrae on the West coast of Greenland has almost doubled its speed since 2000 from ...

2008-01-31

248

Microstructural Coarsening during Thermomechanical Fatigue and Annealing of Micro Flip-Chip Solder Joints

Magnetic resonance imaging: early detection of central nervous system involvement in acquired immunodeficiency syndrome (AIDS)

Microstructural evolution due to thermal effects was studied in micro solder joints (55 {+-} 5 {micro}m). The composition of the Sn/Pb solder studied was found to be hypereutectic with a tin content of 65--70 wt%.This was determined by Energy Dispersive X-ray analysis and confirmed with quantitative stereology. The quantitative stereological value of the surface-to-volume ratio was used to characterize and compare the coarsening during thermal cycling from 0--160 C to the coarsening during annealing at 160 C. The initial coarsening of the annealed samples was more rapid than the cycled samples, but tapered off as time to the one-half as expected. Because the substrates to which the solder was bonded have different thermal expansion coefficients, the cycled samples experienced a mechanical strain with thermal cycling. The low-strain cycled samples had a 2.8% strain imposed on the solder and failed by 1,000 cycles, despite undergoing less coarsening than the annealed ...

1998-12-01

249

Magnetic resonance imaging in patients with heart valve prostheses

Central Nervous System (CNS) involvement, whether primary by the Human Immunodeficiency Virus - HIV - itself, or secondary (toxoplasmosis or lymphoma) is remarkably frequent in AIDS, in 40 to 70% of cases, depending upon the author. In order to study the natural history of this illness, a cohort of 25 asymptomatic seropositive patients have been established. Every 6 months these patients undergo biological and clinical examinations, as well as Magnetic Resonance brain scans. After two examinations at a 6 month's interval, the first results are reported. Out of these 25 cases, 9 present anomalies: One patient with diffuse cerebral atrophy and 8 others with high signal intensity areas on T2 weighted sequences, like those of the Multiple Sclerosis. No relationship could be demonstrated between the existence of these lesions and various criteria such as age, sex, risk factors and T4 cells count. The nature of these lesions is not lear. They certainly indicate early ...

250

Kinetics of complexing activation by the magnesium ion on green crab (Scylla serrata) alkaline phosphatase.

Artifical valve prostheses are often regarded as a contraindication for magnetic resonance imaging (MRI), although preliminary in vitro studies suggested, that patients with these metallic implants might safely undergo MR examination. This study reports on the experience with a group of 89 patients with 100 heart valve prostheses who were examined by spin-echo MR and gradient-echo MR. MR examination was performed in all patients without complications. The spin-echo sequence showed advantages in the depiction of anatomical structures like paravalvular abcesses. Anatomical structures adjacent to the artificial valve were clearly visivle and the metal components of the valves showes no or only small artifacts. Artifacts were accentuated when using gradient-echo sequences. Gradient-echo sequences provided valuable information regarding the presence of valvular insufficiency. Physiological valvular regurgitation was easy to differentiate from pathological paravalvular ...

251

Iron Aluminide Hot Gas Filters

As with mammalian enzymes, green crab (Scylla serrata) alkaline phosphatase can be activated by Mg2+ through a time-dependent course. The activation is mainly a Vmax effect. Tsou's method was used to study the kinetic course of activation. The results show that the enzyme was activated by a complexing scheme that had not been previously identified: the enzyme first reversibly and quickly binds Mg2+ and then undergoes a slow reversible course to activation, with a relatively high activation energy (78 +/- 4 kJ/mol) and a slow conformational change. The activation reaction is a single molecule reaction, and the apparent activation rate constant is independent of Mg2+ concentration if the concentration is sufficiently high. The microscopic rate constants of activation and the association constant were determined from the measurements. The proposed scheme may also be applied to the Mg2+ activation mechanism for mammalian enzyme, to explain why the activation rate is ...

2001-01-01

252

Iodixanol in cerebral computed tomography: a randomized, double-blind, phase-III, parallel study with iodixanol and iohexol

Currently, high temperature filter systems are in the demonstration phase with the first commercial scale hot filter systems being installed on integrated gasification combined cycle (IGCC) and pressurized fluid bed combustion cycle (PBFC) systems (70 MW). They are dependent on the development of durable and economic high temperature filter systems. These filters are mostly ceramic tubes or candles. Ceramic filter durability has not been high. Failure is usually attributed to mechanical or thermal shock: they can also undergo significant changes due to service conditions. The overall objective of this project is to commercialize weldable, crack resistant filters which will provide several years service in advanced power processes. The specific objectives of this project are to develop corrosion resistant alloys and manufacturing processes to make Iron Aluminide filter media, and to use a ``short term`` exposure apparatus supported by other tests to identify the ...

1996-12-31

253

Interaction of tetravalent plutonium and zirconium with citric acid in nitric acid solutions

Iodixanol is a new nonionic dimer, isotonic with blood at all clinically relevant concentrations. Iodixanol (270 mg I/ml) was compared in a double-blind, randomized, parallel-group, phase-III study to the monomeric nonionic iohexol (300 mg I/ml) for evaluation of safety, tolerability and radiographic efficacy during cerebral CT. One hundred adult patients scheduled to undergo contrast-enhanced cerebral CT were randomly allocated to receive either iodixanol or iohexol. All completed the trial. Safety was evaluated by recording discomfort and other adverse events, tolerance by assessing intensity and incidence of discomfort. Radiographic efficacy was assessed from the diagnostic information and the radiographic density. No serious adverse events occurred. One patient (2 %) in the iodixanol group and one patient (2 %) in the iohexol group experienced a transient reddening at the neck and lower neck-line, respectively. Both contrast agents were well tolerated. One ...

1999-09-01

254

Influence of sigma-phase formation on the localized corrosion behavior of a duplex stainless steel

The interaction of Pu(IV) and Zr(IV) with citric acid in nitric acid solutions (C/sub HNO/sub 3// greater than 0.1 M) of lithium nitrate was studied by the distribution method in the interval of nitrate ion concentrations from 1 to 6 g-eq/liter. A 40 percent solution of TBP in decane was used as the extraction reagent. It was established that within the range of concentrations studied, complex compounds of plutonium and zirconium are formed: PuHCit/sup 2 +/ and ZrH/sub 2/Cit/sup 3 +/. The concentration equilibrium constants of the reactions of formation of these compounds retain a constant value at constant ionic strength and undergo substantial variation when the total concentration of the nitrate ion in solution is varied. The values of the effective equilibrium constants, calculated considering the change in the activity coefficient of the hydrogen ion, retain a constant value within a wide range of nitrate ion concentrations. It was shown that the effectiveness ...

1975-01-01

255

In-situ and post-irradiation fatigue properties of the ferritic-martensitic steel Manet at T=250 C

Because of their austenitic-ferritic microstructures, duplex stainless steels offer a good combination of mechanical and corrosion resistance properties. However, heat treatments can lower the mechanical strength of these stainless steels as well as render them susceptible to intergranular corrosion (IGC) and pitting corrosion. In this study, a low-carbon (0.02%) duplex stainless steel is subjected to various heat treatments at 450 to 950 C for 30 min to 10 h. The heat-treated samples than undergo ASTM IGC and pitting corrosion tests, and the results are correlated with the microstructures obtained after each heat treatment. In the absence of Cr_2_3C_6 precipitation, #sigma#-phase precipitates render this duplex stainless steel susceptible to IGC and pitting corrosion. Even submicroscopic #sigma#-phase precipitates are deleterious for IGC resistance. Longer-duration heat treatments (at 750 to 850 C) induce chromium diffusion to replenish the chromium-depleted ...

1996-01-01

256

Hydrogen isotope effects in hydride transfer reactions of formaldehyde and glyoxal

Strain controlled fatigue experiments on the modified ferritic-martensitic 12% Cr-steel Manet have been performed during, after and without irradiation. Continuous push-pull cycling of the hollow fatigue specimens with a cycle ratio R=-1, an axial strain rate of 8.10{sup -4} s{sup -1} and total strain ranges {Delta}{epsilon}{sub t} between 0.42% and 1.0% has been applied in vacuum (5.10{sup -3} Pa) at T=250 C. For the irradiation, a 104 MeV {alpha}-particle beam was used. Compared to unirradiated specimens, in-beam specimens undergo irradiation hardening at an advanced fatigue/implantation stage. Post-irradiation specimens show significantly higher total stress amplitudes and reduced fatigue lives. TEM investigations of in-beam and post-irradiation specimens reveal helium bubbles with different diameters on internal surfaces and in the matrix. (orig.).

1996-10-01

257

High-pressure Raman study on CeO{sub 2} nanospheres self-assembled by 5 nm CeO{sub 2} nanoparticles

In the presence of hydroxyl anion, both formaldehyde and glyoxal are known to undergo rearrangements involving intermolecular and intramolecular hydride transfer (the Cannizzaro and Benzilic acid rearrangements respectively). The authors report ab initio SCF-MO calculations of the transition state geometries, the activation barriers, and the hydrogen isotope effects for these two reactions. The structure of the transition state for the rection involving formaldehyde is usually basis set dependent, becoming more linear and symmetrical as the basis set size increases. In contrast, the analogous transition state for the glyoxal reaction involves a highly non-linear hydride transfer. They find the isotope effects to be quite low for the Cannizzaro reaction, and significantly larger for the non-linear benzilic acid rection, in apparent contradiction to Westheimer's suggestion the isotope effects reach a maximum for linear hydrogen transfers. Since this hypothesis does ...

1987-04-01

258

CeO{sub 2} undergoes a first-order phase transition from fluorite to {alpha}-PbCl{sub 2}-type structure under high pressure. To evaluate the changes in physical properties of CeO{sub 2} nanomaterials as the particle size decreasing, high-pressure Raman study under quasi-hydrostatic condition has been performed on CeO{sub 2} nanospheres self-assembled by 5 nm CeO{sub 2} nanoparticles at room temperature. Surprisingly, as the pressure elevate to 34 GPa, the CeO{sub 2} nanospheres still retain the cubic fluorite-type structure, indicating the sample is more stable than the bulk counterpart. Whereas, previous high-pressure studies show the phase transition at 22.3/26.5 GPa for 12 nm CeO{sub 2} nanoparticles, which is less stable than the bulk materials. The enhancement of phase stability might be attributed to the increase of surface energy of CeO{sub 2} nanospheres as the size of the building units decrease. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. ...

2011-05-15

259

British Library Electronic Table of Contents (United Kingdom)

This study was performed to assess the possibility that patient age may independently affect improvements in health-related quality of life following percutaneous coronary intervention. One hundred five patients undergoing elective percutaneous coronary intervention at a single tertiary referral center between January 10, 2001 and January 6, 2002 were enrolled and prospectively evaluated. Health-related quality of life was assessed before and 1 year following percutaneous coronary intervention using Short Form-12 and the Seattle Angina Questionnaire. For the purpose of analysis, patients were divided according to age (younger than 60, 60-70, and older than 70 years). One hundred patients (95%) completed both questionnaires. Baseline characteristics among the age groups were similar in terms of gender, cardiac risk factors, and procedural details. All health-related quality-of-life indices demonstrated improvements with at least four variables in each group ...

260

Percutaneous coronary revascularisation [PCR] improves angina and health related quality of life [HRQOL] compared to standard medical therapy. It is unknown whether PCR has the same benefits for patients with a history of CABG. Over a period of 5?years, we assessed HRQOL of patients undergoing PCR using Part 1 of the Nottingham Health Profile [NHP] at baseline 3, 12 and 24?months. We compared HRQOL after PCR in 255 patients with CABG to 2680 without. There were more males [81.1% v 69.6% p?=?0.002] and older patients [mean age 60.1?years v. 58.0 p?=?0.03] in CABG group. Perceived HRQOL improved at 24?months for pain, energy and emotional reaction but the improvement was less in the CABG group. However, mean NHP scores at 24?months for those with CABG had returned to baseline levels for slee...

2011-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

261

Hanford facility dangerous waste permit application, general information portion

Formation of methyl formate and other organic species in the warm-up phase of hot molecular cores

The `Hanford Facility Dangerous Waste Permit Application` is considered to be a single application organized into a General Information Portion (this document, DOE/RL-91-28) and a Unit- Specific Portion. The scope of the General Information Portion includes information that could be used to discuss operating units, units undergoing closure, or units being dispositioned through other options. Documentation included in the General Information Portion is broader in nature and could be used by multiple treatment, storage, and/or disposal units. A checklist indicating where information is contained in the General Information Portion, in relation to the Washington State Department of Ecology guidance documentation, is located in the Contents Section. The intent of the General Information Portion is: (1) to provide an overview of the Hanford Facility; and (2) to assist in streamlining efforts associated with treatment, storage, and/or disposal unit-specific Part B permit ...

1996-07-29

262

Focal lesions in external auditory canal: computed tomography images

Aims: The production of saturated organic molecules in hot cores and corinos is not well understood. The standard approach is to assume that, as temperatures heat up during star formation, methanol and other species evaporate from grain surfaces and undergo a warm gas-phase chemistry at 100 K or greater to produce species such as methyl formate, dimethyl ether, and others. But a series of laboratory results shows that protonated ions, typical precursors to final products in ion-molecule schemes, tend to fragment upon dissociative recombination with electrons rather than just ejecting a hydrogen atom. Moreover, the specific proposed reaction to produce protonated methyl formate is now known not to occur at all. Methods: We utilize a gas-grain chemical network to probe the chemistry of the relatively ignored stage of hot core evolution during which the protostar switches on and the temperature of the surrounding gas and dust rises from 10 K to over 100 K. During this ...

2006-01-01

263

Facial osteomyelitis as complication of chronic sinusitis in hemophiliac-AIDS patients - scintigraphic evaluation with technetium-99m-MDP and Gallium-67; Osteomielitis da face como complicacao de sinusite cronica em hemofilicos aideticos - avaliacao cintilografica com {sup 99m} Tc-MDP e {sup 67} Ga

To analyze and review the most common focal lesions of the external auditory canal (EAC), describing the computed tomography (CT) findings. The CT images of EAC were reviewed in a series of 167 patients. Abnormal findings were recorded in 13 cases. The CT images were correlated with otoscopic and/or intraoperative findings. There were four cases of osteoma (one located outside the EAC); all of which were treated surgically, as was the one case of exostosis. Six patients presented debris in EAC, coinciding with clinical evidence of external otitis. There were two cholesteatomas derived from EAC, one of them secondary to survery to treat osteoma. On patient was diagnosed as having a basal cell carcinoma of the ear, extending to EAC, but refused to undergo surgery. Five patients presented small triangular laminae of dense bone arising from the upper wall of the EAC which were defined as abnormal variants of the fusion of the temporal squamous epithelium to the ...

264

Explosions of chaotic sets

In the paper six cases of facial osteomyelitis as a complication of chronic sinusitis in hemophiliac-AIDS patients are reported. Osteomyelitis was suggested by an increasing of erythrocyte sedimentation rate. The diagnosis was confirmed by a positive {sup 99m} Tc MDP scintigraphy. The patients were submitted to clinical treatment. The erythrocyte sedimentation rate and 67-gallium citrate scans were used in the follow-up of the therapy. Three patients had negative gallium after three weeks of organism-specific antibiotic therapy; in two patients the gallium scintigraphy remained positive. One patient did not undergo the radionuclide scan for this clinical conditions. These results suggest that MDP scans showed higher sensitivity and specificity in detection of bone disease in chronic sinusitis. Gallium scans appeared to be valuable tool in the follow-up of the infection. There are no reports in the literature of osteomyelitis as a complication of chronic sinusitis ...

1997-01-01

265

Exploring the mechanism of radiation-enhanced hepatocellular carcinoma cell invasion by swept source optical coherence tomography

Large-scale invariant sets such as chaotic attractors undergo bifurcations as a parameter is varied. These bifurcations include sudden changes in the size and/or type of the set. An explosion is a bifurcation in which new recurrent points suddenly appear at a non-zero distance from any pre-existing recurrent points. We discuss the following. In a generic one-parameter family of dissipative invertible maps of the plane there are only four known mechanisms through which an explosion can occur: (1) a saddle-node bifurcation isolated from other recurrent points, (2) a saddle-node bifurcation embedded in the set of recurrent points, (3) outer homoclinic tangencies, and (4) outer heteroclinic tangencies. (The term ``outer tangency'' refers to a particular configuration of the stable and unstable manifolds at tangency.) In particular, we examine different types of tangencies of stable and unstable manifolds from orbits of pre-existing invariant sets. This leads to a ...

2000-09-01

266

Effects of freeze-thaw cycles on the performance of soft materials used in soil covers with capillary barrier; Effets des cycles de gel-degel sur la performance des materiaux meubles utilises dans les couvertures a effets de barriere capillaire

Ionizing radiation is a standard treatment for various human solid tumors. However, several clinical studies showed that a significant proportion of patients undergoing radiotherapy for hepatocellular carcinoma (HCC) develop intrahepatic and extrahepatic metastasis. Understanding of radiation-induced cancer cell invasiveness and behavior is essential and of great important for developing suitable treatment strategies to contain cancer spread. Therefore, in this study we evaluated the effectiveness of using swept source optical coherence tomography (SS-OCT) to monitor the enhancement of HCC cell invasiveness by radiation. SS-OCT images were acquired and recorded to obtain three-dimensional data sets per four hours in 48 hours after irradiating HepG2 cells with 7.5 Gy. The cell migration behavior in three-dimensional tissue models was quantified from images of radiation-induced and sham-irradiated cells.

2011-02-01

267

Effect of paraquat on microsomal lipid peroxidation in vitro and in vivo. [Rats, rabbits, man, mice

Freezing and thaw have an effect on soils, and the effect of the freeze-thaw cycle on soil covers used in the control of acid mine drainage was discussed in this poster presentation. The purpose of soil covers in cases involving acid mine drainage (AMD) is to reduce the exposure of tailings to oxygen which cause AMD. The effect of this freezing-thaw cycle on soft materials used in soil covers with capillary effect was studied. Some laboratory experiments were conducted to evaluate the properties of the moisture retention layer. The preliminary results were presented. The results indicated that the freeze-thaw cycle might affect the performance of soil covers in the long term, depending on the type of materials selected. Further research is undergoing. 26 figs.

2000-07-01

268

Dynamic interpretation of organic-matter maturation and evolution of oil-generative window

Rat lung and liver microsomes did not undergo lipid peroxidation in the absence of iron when incubated with NADPH and concentrations of paraquat ranging from 10/sup -7/ to 10/sup -2/ M. Paraquat also did not stimulate rat liver and lung microsomal peroxidation induced by added iron and NADPH, and was inhibitory at concentrations above 10 ..mu..M. Similarly, no stimulation of peroxidation was produced by paraquat in rabbit or human lung microsomes; however, under similar conditions, paraquat enhanced NADPH/iron-dependent peroxidation in mouse lung and liver microsomes obtained from rats sacrificed at 12, 18, and 24 hr following a lethal dose of paraquat (50 mg/kg, ip), there was no loss of vitamin E or increase in susceptibility to in vitro peroxidation which would be expected if lipid peroxidation had occurred in vivo although extensive lung damage developed during this time period. These results indicate that paraquat does not cause pulmonary toxicity by ...

1980-01-01

269

Direct measurement of the alpha-epsilon transition stress and kinetics for shocked iron

Two phases are recognized in the maturation of organic matter and evolution of the oil-generative window (OGW): (a) a basinal subsidence phase during which potential source rocks undergo burial through a static initial OGW, and maturation is due essentially to increasing temperature with depth, and (b) a postsubsidence phase during which the OGW moves vertically upward through the static sedimentary fill, and maturation is due to time effects. Only the final shallow position of OGW can be defined by geochemical indices of maturity. The hydrocarbon generation sequence progresses from bottom to top, beginning with the lighter hydrocarbons (or even thermogenic gas) at the initial OGW at depth, followed by progressively heavier hydrocarbons as the OGW moves vertically upward. This dynamic model of hydrocarbon generation permits modeling of past positions of OGW relative to basin evolution through interpretation of oil-genesis nomographs. It also provides genetic ...

1984-08-01

270

Conversion of a plasma enhanced chemical vapor deposited silicon-carbon-nitride thin film at ultra-low temperature by oxygen plasma

Iron undergoes a polymorphic phase transformation from alpha phase (bcc) to the epsilon phase (hcp) when compressed to stresses exceeding 13 CPa. Bccause the epsilon phase is denser than the alpha phase, a single shock wave is unstable and breaks up into an elastic wave, a plastic wave, and a phase transition wave. Examination of this structured wave coupled with various phase transformation models has been used to indirectly examine the transition kinetics. Recently, multimillion atom simulations (molecular dynamics) have been used to examine the shock-induced transition in single crystal iron illustrating an orientation dependence of the transition stress, mechanisms, and kinetics. The objective of the current work was to perform plate impact experiments to examine the shock-response of polycrystalline and single crystal iron with nanosecond resolution for impact stresses spanning the {alpha} - {epsilon} transition. The current data reveal an orientation ...

2009-01-01

271

Combining anatomy and function: the path to true image fusion

In this work we present an ultra-low temperature method for the oxidation of an amorphous silicon-carbide-nitride (SiCN) material. The SiCN is deposited on silicon substrates by plasma enhanced chemical vapor deposition using CH{sub 4}, SiH{sub 4}, and N{sub 2} chemistry. The physical and chemical properties are characterized for the as-deposited SiCN and post-oxidized films are discussed. The SiCN film is exposed to oxygen plasma, where it undergoes a chemical transformation into a binary SiO{sub 2} material system. A 1.7 nm/min oxidation rate is typical for this process and compares favorably to oxidation methods utilizing much higher temperatures. The substrate temperature remains extremely low throughout the oxidation process, T{sub s} < 200 deg. C. Changes in film stress, optical constants, film thickness, surface roughness, and film density are measured. Chemical analysis by X-ray photoelectron spectroscopy is reported for both the as-deposited and ...

2008-01-30

272

Combined peritoneography and computerized tomography for evaluating abdominal complications in patients undergoing continuous peritoneal dialysis

Modern imaging technologies visualize different aspects of disease in a non-invasive way. Considerable progress has been made in the fusion of images from different imaging modalities using software approaches. One goal of fusion software is to align anatomical and functional images and allow improved spatial localization of abnormalities. The resulting correlation of the anatomical and functional images may clarify the nature of the abnormality and help diagnose or stage the underlying disease. Whereas successful image fusion software has been developed for the brain, only limited success has been achieved for image alignment in other parts of the body. The development and current status of alternative approaches are presented. Dual-modality imaging is described with devices where two modalities are combined and mounted in a single gantry. The use of existing scanner technology ensures that no compromises are made in the clinical efficacy of either the anatomical or functional imaging ...

2001-10-01

273

Combination adjuvant chemotherapy with oxaliplatin, 5-fluorouracil and leucovorin after liver transplantation for hepatocellular carcinoma: a preliminary open-label study

Continuous ambulatory peritoneal dialysis (CAPD) is a generally well-tolerated treatment. However, some patients exhibit such complications as to prevent the continuation of treatment. Peritonitis is the major problem, but the continuation of treatment may also be undermined by different complications, such as peritoneal leakage, hernia, catheter malfunctioning, and scrotal-penile edema; a careful investigation of the patient is always needed in such cases. From November 1985 to February 1990, we examined 20 patients, who had presented with different types of complications in the course of dialysis. Peritoneography demonstrated 3 cases of abdominal hernias, 2 cases of patency of the peritoneal-vaginal duct, and 2 cases of catheter obstruction. Peritoneal CT allowed the identification of leakage in 3 patients, while the combined use of the two techniques showed adhesions or pathologic peritoneal recesses in 7 cases. In 3 patients normal patterns were observed. Peritoneography, ...

1985-11-01

274

British Library Electronic Table of Contents (United Kingdom)

Summary The purpose of this study was to evaluate the efficacy of postoperative adjuvant chemotherapy with FOLFOX regimen on the outcome after LT for HCC patients who did not meet the Milan criteria. Ninety-five consecutive HCC patients with liver cirrhosis undergoing LT were enrolled. Fifty-eight who did not meet the Milan criteria were randomized to open-label treatment with or without adjuvant chemotherapy after LT (n?=?29/group). The FOLFOX chemotherapy protocol comprised 3-week cycles of oxaliplatin 100?mg/m2 on day 1, leucovorin (calcium folinate, CF) 200?mg/m2 on day 1 followed by 3-day, and 5-fluorouracil (5-FU) 2000?mg/m2 as a 48-h continuous infusion, for up to six courses in the 1st year after transplantation. Median survival was extended by 4.57?months by combination chemothera...

2011-01-01

275

Carburization and tensile behavior of alloy 800 in liquid sodium

Carburization and tensile behavior of Alloy 800 in liquid sodium

The carbon transfer has been analyzed in the Alloy 800/sodium/stainless steel system by determining the carbon-uptake of Alloy 800 foils, which were exposed in liquid sodium of known carburizing potential. Under equilibrium condistions between 650 and 550_0C the measured total carbon concentrations in the Alloy 800 tabs were found to be roughly related to the carbon activities of the sodium environment by the equation already stated for the 18 Cr-8/10 Ni stainless steels, extrapolated to the chemical composition of the Ni-rich austenitic alloy. However the Alloy 800 was not found to undergo any decarburization in low-carbon activity environments. The carbon diffusion kinetics was determined as a function of temperature, it was found to be similar to that reported for the AISI-304 type of steel. The effects of sodium exposure on microstructural and mechanical properties of several Alloy 800 heats were examined at 550_0C as a function of the active carbon ...

276

CT-Expo - a novel program for dose evaluation in CT

The carbon transfer has been analyzed in the Alloy 800/sodium/stainless steel system by determining the carbon-uptake of Alloy 800 foils, which were exposed in liquid sodium of known carburizing potential. Under equilibrium conditions between 650 and 550/sup 0/C the measured total carbon concentrations in the Alloy 800 tabs were found to be roughly related to the carbon activities of the sodium environment by the equation already stated for the 18 Cr-8/10 Ni stainless steels, extrapolated to the chemical composition of the Ni-rich austenitic alloy. However the Alloy 800 was not found to undergo any decarburization in low-carbon activity environments. The carbon diffusion kinetics was determined as a function of temperature, it was found to be similar to that reported for the AISI-304 type of steel. The effects of sodium exposure on microstructural and mechanical properties of several Alloy 800 heats were examined at 550/sup 0/C as a function of the active carbon ...

1983-05-01

277

CO{sub 2} trading systems undergo quiet experimentation

CT-Expo is a novel MS Excel application for assessing the radiation doses delivered to patients undergoing CT examinations, based on computational methods that were used to analyze the data collected in the German survey on CT practice in 1999. The program enables the calculation of all dose quantities of practical value, such as axial dose free-in-air, weighted CTDI, dose-length product, effective dose and uterine dose. In contrast to existing programs for CT dose assessment, CT-Expo offers a number of unique features, such as gender-specific dose calculation for all age groups (adults, children, newborns), applicability to all existing scanner models including correction of scanner-specific influences, and the possibility of comparison with the results from the German CT survey on CT practice. Three different application modules offer free and standardized dose calculations as well as a comprehensive benchmarking section including guidance on dose optimization. ...

2002-12-01

278

Binary Pseudo-random Grating Standard for Calibration of Surface Profilometers

Issues regarding the development of mechanisms to reduce greenhouse gas emissions in the electricity sector are discussed. Environmental groups have proposed mechanisms such as carbon taxes. Three other mechanisms have also been proposed under the Framework Convention on Climate Change (FCCC). These include the Clean Development Mechanism, Joint Implementation and carbon trading. A pilot emission reduction trading project began in Ontario in 1996 as an initiative to control smog and ozone in the southern provincial airshed. Substances of interest include NO{sub x}, volatile organic compounds (VOCs), SO{sub x}, carbon monoxide and other greenhouse gases. Ontario Hydro alone has conducted 10 trades, five with companies in the U.S., two of those for carbon emissions. An analysis of the pilot trade deals will provide an idea of the value of this mechanism. In addition to details of the trades, this article also addresses concerns regarding the degree to which any country should be allowed ...

1999-02-01

279

Atelectasis on pediatric chest CT: comparison of sedation techniques

We suggest and describe the use of a binary pseudo-random (BPR) grating as a standard test surface for measurement of the modulation transfer function (MTF) of interferometric microscopes. Knowledge of the MTF of a microscope is absolutely necessary to convert the measured height distribution of a surface undergoing metrology into an accurate power spectral density (PSD) distribution. For an'ideal' microscope with an MTF function independent of spatial frequency out to the Nyquist frequency of the detector array with zero response at higher spatial frequencies, a BPR grating would produce a flat 1D PSD spectrum, independent of spatial frequency. For a'real' instrument, the MTF is found as the square root of the ratio of the PSD spectrum measured with the BPR grating to the'ideal,' spatial frequency independent, PSD spectrum. We present the results from a measurement of the MTF of MicromapTM-570 interferometric ...

2008-01-16

280

Assessment of the role of oxygen and mitochondria in heat shock induction of radiation and thermal resistance in Saccharomyces cerevisiae

Background. A change in practice at our institution resulted in increased use of anesthesia for CT scan of the chest in children who required sedation. Objective. To determine whether there is a difference in the frequency or severity of pulmonary atelectasis on CT scan in children sedated by anesthesiologists compared with children sedated by radiologists using intravenous pentobarbital. Materials and methods. Retrospective blinded review of 60 CT scans of the chest performed in 41 children. Forty-one studies in children sedated by radiologists (median age 29 months) were compared with 19 studies in children sedated by anesthesiologists (median age 25 months). Results. Atelectasis sufficient to obscure pulmonary metastases was shown in 5 of 41 (12 %) radiology sedations and 13 of 19 (68 %) anesthesiology sedations (P < 0.01). Higher grades of atelectasis were recorded in children under anesthesia (P < 0.01). Conclusion. Atelectasis is more frequent and more severe in children ...

1999-07-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

281

Analytical model for the dynamic resistivity of electrically-exploded conductors

In response to a heat shock, the yeast Saccharomyces cerevisiae undergoes a large increase in its resistance to heat and, by the induction of its recombinational DNA repair capacity, a corresponding increase in resistance to radiation. Yeast which lack mitochondrial DNA, mitochondria-controlled protein synthetic apparatus, aerobic respiration, and electron transport (rho/sup 0/ strain) were used to assess the role of O/sub 2/, mitochondria, and oxidative processes controlled by mitochondria in the induction of these resistances. We have found that rho/sup 0/ yeast grown and heat shocked in either the presence or absence of O/sub 2/ are capable of developing both radiation and heat resistance. We conclude that neither the stress signal nor its cellular consequences of induced heat and radiation resistance are directly dependent on O/sub 2/, mitochondrial DNA, or mitochondria-controlled protein synthetic or oxidative processes.

1983-10-01

282

An investigation of the production of thin films of some materials which undergo phase transitions for optical applications

A detailed model for the dynamic resistivity of an exploding conductor presents many difficulties. An electrically-exploded conductor undergoes significant hydrodynamic expansion as it is heated. Resistivity is a function of both the temperature and density of a conductor and realistic models for resistivity over the range of parameter space experienced by an exploding conductor are quite complex. See for example, the model of Lee and More (1984). Calculation of the hydrodynamic expansion of the conductor during and subsequent to the explosion is likewise dependent on detailed knowledge of the equation of state for the conductor in a range where few experimental data exist. A further complication is the strong magnetic field which couples the hydrodynamic expansion to the currents flowing in the expanding material. In spite of the difficulties, progress is being made on detailed modeling of fuses and exploding conductors (Lidemuth and co-workers, 1985). A simpler ...

1986-10-10

283

Adaptive response of the chicken embryo to low doses of x-irradiation

The aim of this work was to study the possibility of producing a fast switching optical thin film device to react to laser radiation in the visible/near infrared region of the spectrum. The switching mechanism was to be thermally driven. A computer program was written to enable the effects of changes of the refractive index of a component of a multilayer thin film stack to be modelled. Attempts to use the phase transition in vanadium dioxide were unsuccessful because, in the spectral region of interest, the 'open-state' absorption was too great. A class of materials known as 'the bronzes' was identified as being potentially useful. Attempts were made to produce thin films of bronze compounds of vanadium, tungsten and molybdenum by the techniques of conventional thermal evaporation and laser ablation for further studies. The former technique appeared to suffer from problems of decomposition of the source material. The latter technique showed greater promise although loss of oxygen was a ...

1995-01-01

284

A quantitative structural analysis of the low temperature phase of lithium-7

Chicken embryos were x-irradiated in ovo with 5-30 cGy (=priming dose) at the 13th-15th day of development. After 3-48 h, brain- and liver-cell suspensions were x-irradiated in vitro with (challenge) doses of 4-32 Gy. Significantly less radiation damage was observed when the radiation response was measured by scheduled DNA synthesis, nucleoid sedimentation and viscosity of alkaline cell lysates 12-36 h after the priming exposure. In vivo, pre-irradiation with 10 cGy enhanced regeneration as evidenced by the DNA content of chicken embryo brain and liver 24 h following a challenge dose of 4 Gy. From nucleoid sedimentation analyses in brain and liver cells immediately after irradiation with 16 Gy and after a 30-min repair period in the presence of aphidicolin, dideoxythymidine and 3-aminobenzamide or in the absence of these DNA repair inhibitors, it is concluded that a reduction of the initial radiation damage is the dominant mechanism of the ``radio-adaptive`` response of the chicken ...

1995-08-01

285

A prospective study of 100 roboticallyassisted laparoscopic adrenalectomies

Calculations in "7Li have been carried out for the differential coherent elastic scattering cross-section of thermal neutrons at a fixed scattering angle #theta#_0(148"o) and varying the energy of incident neutrons (or corresponding d-spacings). The results are reported, as variations of the ratio #SIGMA#_0"c"o"h (#theta#_0, d)/#SIGMA#_0"c"o"h (#theta#_0) with d-spacing, at atmospheric pressure and at two temperatures, 80 and 20 K. The calculations at 80 K correspond to BCC lithium whereas at 20 K all the possible crystallographic structures of polytype lithium (BCC, 9R, HCP and FCC) were considered. On comparing our results with the time-of-flight (TOF) measurements of Berliner et al. (Physical Review, B40, 12086, 1989) we find that up to 80 K lithium-7 does not undergo any martenistic transformation whereas the structural state at 20 K can be described by the co-existence of the original BCC phase with 9R, HCP and FCC closed packed structures. A quantitative ...

286

British Library Electronic Table of Contents (United Kingdom)

We evaluated robotically assisted laparoscopic adrenalectomy (RLA) in a prospective study of 100 consecutive patients (60 women and 40 men) undergoing unilateral adrenalectomy at the University Hospital. The median age was 59 (24?82) years and BMI 27.6 (17.1?40.9) kg/m2. Preoperative diagnoses were Conn?s syndrome 30%, pheochromocytoma 23%, Cushing syndrome 27% and non-functional tumor 20%. The median tumor size was 53 (10?106) mm. The majority of the 7% of the patients who were converted to open surgery were in the early phase after the introduction of the technique. The BMI of the patients who were converted to open surgery was significantly higher, 31.5 (range 25.3?37.8) compared to, 27.5 (range 17.1?40.9) in patients without conversion (P?=?0.047). The median weight of the tumor was 51...

2011-01-01

287

A Glance into the Future of Human Computer Interaction

Decay of {sup 177}T{sub a} composite nucleus. Comparison of excitation functions for the reaction residues occurring in {sup 12}C + {sup 165}H{sub 0} and {sup 14}N + {sup 163}D{sub y} reactions

Computers have a direct impact on our lives nowadays. Human's interaction with the computer has modified with the passage of time as improvement in technology occurred the better the human computer interaction became. Today we are facilitated by the operating system that has reduced all the complexity of hardware and we undergo our computation in a very convenient way irrespective of the process occurring at the hardware level. Though the human computer interaction has improved but it's not done yet. If we come to the future the computer's role in our lives would be a lot more rather our life would be of the artificial intelligence. In our future the biggest resource would be component of time and wasting time for a key board entry or a mouse input would be unbearable so the need would be of the computer interaction environment that along with the complexity reduction also minimizes the time wastage in the human computer interaction. Accordingly in our future the ...

2011-01-01

288

Utilizing the right mix of environmental cleanup technologies

The experimental has been performed with a view to studying complete and incomplete fusion in {sup 14}N + {sup 163}D{sub y} system below 7 MeV/nucleon. The excitation functions for several reactions have been measured using the activation technique and compared with the theoretical predictions based on statistical models. The codes ALICE-91 and CASCADE used earlier for the analysis of excitation functions in case of {sup 12}C + {sup 165}H{sub 0} system have been used here also with the same set of input parameters. It has been observed that the theoretical calculations do not match with the experimental excitation functions well but the overall shape of the excitation function is reproduced satisfactorily. The composite nucleus ({sup 177}T{sub a}) formed in this ({sup 14}N + {sup 163}D{sub y}) case is the same as the one formed in {sup 12}C + {sup 165}H{sub 0} system studied earlier. Measured excitation functions for the same decay channels in the two cases (i.e. {sup 12}C + {sup ...

2002-10-01

289

Utilization of lightweight materials made from coal gasification slags. Quaterly report, March 1, 1997--May 30, 1997

The Savannah River Site (SRS) is a 310-square-mile United States Department of Energy nuclear facility located along the Savannah River near Aiken, South Carolina. During operations, which started in 1951, hazardous substances (chemicals and radionuclides) were released to the environment. The releases occurred as a result of inadvertent spills and waste disposal in unlined pits and basins which was common practice before environmental regulations existed. The hazardous substances have migrated to the vadose zone and groundwater in many areas of the SRS, resulting in 515 waste units that are required by environmental regulations, to undergo characterization and, if needed, remediation. In the initial years of the SRS environmental cleanup program (early 1990's), the focus was to use common technologies (such as pump and treat, air stripping, excavation and removal) that actively and tangibly removed contamination. Exclusive use of these technologies required ...

2007-09-02

290

Use of sanitary sewers as wastewater pre-treatment systems

The integrated-gasification combined-cycle (IGCC) process is an emerging technology that utilizes coal for power generation and production of chemical feedstocks. However, the process generates large amounts of solid waste, consisting of vitrified ash (slag) and some unconverted carbon. In previous projects, Praxis investigated the utilization of {open_quotes}as-generated{close_quotes} slags for a wide variety of applications in road construction, cement and concrete production, agricultural applications, and as a landfill material. From these studies, we found that it would be extremely difficult for {open_quotes}as-generated{close_quotes} slag to find large-scale acceptance in the marketplace even at no cost because the materials it could replace were abundantly available at very low cost. It was further determined that the unconverted carbon, or char, in the slag is detrimental to its utilization as sand or fine aggregate. It became apparent that a more promising approach would be ...

1998-12-31

291

U. S. Navy shipboard-generated plastic-waste pilot-recycling program. Research and development report, Apr 90-Jan 91

As wastewater travels through a sewer system it undergoes changes in composition. The changes in composition may be caused by chemical, physical and/or biological processes. At present engineers do not take into consideration the impacts of these processes on the wastewater quality when designing wastewater treatment systems. However, the impact of these processes on the chemical oxygen demand, biochemical oxygen demand, nitrogen and phosphorus content of the wastewater can be significant. In the case of the biological processes, microorganisms present in the water as it travels through the sewer system are similar to those found in an activated sludge process. Given that the microorganism population and the hydraulic retention time often resembles that of an activated sludge process, it would seem only reasonable to look further into the possibility of using sewers as wastewater treatment systems. Furthermore, the plug flow regime of a sanitary sewer is inherently ...

1998-12-31

292

Tunable far infrared laser spectroscopy of Van der Waals molecules in a planar supersonic jet expansion

From April 1990 through January 1991, the feasibility of recycling Navy shipboard-generated plastic wastes was explored. Normally, plastic wastes are source separated aboard Navy ships and retained for shoreside disposal in accordance with new fleet requirements implementing MARPOL Annex V that prohibits the discharge of plastics at sea. Over 23,000 pounds of shipboard plastic wastes from USS Lexington (AVT 16) and ships from the Norfolk Naval Base were recycled into park benches, picnic tables and carstops that have been distributed back to the Navy bases for use. Navy shipboard plastics must undergo sorting prior to recycling because Navy plastic waste contains large quantities of composite plastic items (e.g., plastic/paper) that are not easily recyclable. Recycling food-contaminated plastics is not practical due to sanitation problems encountered during handling. However, certain items have good resale value if separated by resin type and color (e.g., sonobuoy ...

1991-03-01

293

Tilt-a-Worlds: Effects of High Rates of Obliquity Change on the Habitability of Extrasolar Planets

The gas phase high resolution spectroscopic study of weakly bound clusters can provide the information necessary to develop an intermolecular potential energy surface. This surface can then be used to better understand condensed phases. In this work, a tunable far infrared laser spectrometer is used to study weakly bound dimers produced in the newly developed continuous planar supersonic jet expansion apparatus. The water dimer is an extensively studied hydrogen bonded dimer. It undergoes several tunneling motions which result in splittings and perturbations of the rovibrational energy levels. A review is presented of much of the experimental and theoretical work done on water dimer, including a description of the combined fit of all the high resolution spectroscopic results by Coudert and Hougen. Also included is a discussion of the measurement of the K = 1 lower {yields} K = 2 lower band performed using the tunable far infrared laser/planar jet apparatus. The ...

1990-12-01

294

The thorny path linking cellular senescence to organismalaging

We explore the impact of obliquity variations on planetary habitability in hypothetical systems with high mutual inclination. For the hypothetical systems, we restrict our exploration to systems consisting of a solar-mass star, an Earth-mass planet at 1 AU, and 1 or 2 giant planets. We verify that these systems are stable for 108 years with N-body simulations. We then calculate the obliquity variations induced by the orbital architecture on the Earth-mass planets. We find that in some cases the spin axes can rotate through 360 degrees in as little as 10,000 years (John is that right? Can you look through the systems and find the most extreme case of obliquity variation?) Next, we run energy balance models (EBM) on the terrestrial planets to assess surface temperature and ice coverage on the planets' oceans. Finally, we explore differences in the outer edge of the habitable zone for planets with rapid obliquity variations. We run EBM simulations for a range of values for the semi-major ...

2011-01-01

295

The clinical application of positron emission tomography to colorectal cancer management

Half a century is fast approaching since Hayflick and colleagues formally described the limited ability of normal human cells to proliferate in culture (Hayflick and Moorhead, 1961). This finding--that normal somatic cells, in contrast to cancer cells, cannot divide indefinitely--challenged the prevailing idea that cells from mortal multicellular organisms were intrinsically ''immortal'' (Carrell, 1912). It also spawned two hypotheses, essential elements of which persist today. The first held that the restricted proliferation of normal cells, now termed cellular senescence, suppresses cancer (Hayflick, 1965; Sager, 1991; Campisi, 2001). The second hypothesis, as explained in the article by Lorenzini et al., suggested that the limited proliferation of cells in culture recapitulated aspects of organismal aging (Hayflick, 1965; Martin, 1993). How well have these hypotheses weathered the ensuing decades? Before answering this question, we first consider ...

2005-08-09

296

The association of asymptomatic bacterial vaginosis with upper genital tract infection.

Colerectal cancer (CRC) is the second commonest cancer in the Western World. Successful treatment relies significantly on accurate detection and staging of primary disease as well as the early identification of the presence and extent of recurrence. Morphological imaging techniques, particularly computed tomography (CT), are well established and widely available to carry out these tasks in addition to predicting and monitoring response to therapy. This review analyses the current inadequacies for imaging CRC and critically assesses the potential role of functional imaging with positron emission tomography (PET). It was reviewed the current literature, to use the experience from the firs 1000 PET studies carried out at the institution and the perspective of surgical colleagues. It was found little evidence for the use of 2-["1"8F]fluoro-2-deoxy-D-glucose (FDG)-PET for screening asymptomatic individuals and current modalities appear better suited for detection of symptomatic primary CRC. ...

2001-09-01

297

The Tropical East Pacific as a Laboratory for Tropical Cyclones

Objective: To determine whether asymptomatic bacterial vaginosis (BV) is associated with upper genital tract inflammation or bacterial colonization.Methods: Fifty nonpregnant women with intact uteri who planned to undergo gynecologic surgery and had no recent symptoms of vaginal infection were enrolled. We obtained a vaginal swab for Gram stain, endocervical swab for chlamydia and gonorrhea DNA probe testing, and Pipelle endometrial biopsy for aerobic and anaerobic cultures and histology. We correlated surgical findings and histology of available surgical specimens with the microbiologic results. The diagnosis of BV was made according to Speigel's criteria. Bacteria isolated from the uterus were classified as high virulence versus low virulence. Contingency tables were analyzed using the chi-square or Fisher Exact tests.Results: Twenty-one of 50 patients had BV on Gram stain, 3 had intermediate BV, and 3 had unreadable slides. Eleven patients had histologic ...

1998-07-01

298

The Differentially Expressed Genes by Radiotherapy in the Patients with Uterine Cervix Cancer

The summertime tropical cyclogenesis rate per unit area in the eastern Pacific ocean is arguably higher than in any other location in the world. Many if not most of these cyclones form from African easterly waves which cross Central America into the Pacific. Of order 25% of these waves intensify into cyclones. A significant fraction of east Pacific tropical cyclones undergoes landfall on the Mexican coast. Those which do not, generally dissipate over cold ocean waters north of the east Pacific intertropical convergence zone, often not far from land. The layer of warm ocean water which supports the development of east Pacific cyclones is unusually shallow and is structured by anticyclonic vortices which form by various processes and propagate slowly to the west. These vortices locally deepen the oceanic mixed layer and support stronger convection than their surroundings, possibly promoting cyclogenesis and cyclone intensification. Cyclones in turn have an ...

2007-05-01

299

Thallium-technetium subtraction parathyroid imaging in patients having previous parathyroid surgery

Purpose : To detect differentially expressed genes in the patients with uterine cervical cancer during the radiation therapy. Materials and Methods : In patients with biopsy proven uterine cervical cancer, we took a tumor tissue just before radiation therapy and at 40 minutes after external irradiation of 1.8 Gy. Total RNAs isolated from non-irradiated and irradiated tumor tissue samples were analyzed using the differential-display reverse transcription-polymerase chain reaction (DDRT-PCR). Complementary DNA (cDNA) fragments corresponding to differentially expressed messenger RNAs(mRNAs) were eluted, and cloned. The differential expression of the corresponding mRNAs was confirmed by reverse northern blot. Differentially expressed cDNA bands were sequenced. Nucleotide sequence data were analyzed in the Gene Bank and EMBL databases via the BLAST network server to identify homologies to known genes or cDNA fragments. Expression pattern of down-regulated clone was examined using RT-PCR in ...

2001-12-15

300

Temperature-induced fusion of small unilamellar vesicles formed from saturated long-chain lecithins and diheptanoylphosphatidylcholine

Parathyroid imaging based on the principle of differential uptakes of Tc-99m and T1-201 in the anterior neck to localize parathyroid (PT) disease has been reported with widely varying results. To evaluate the usefulness of this method, we have performed PT imaging on 47 patients prior to exploratory surgery for PT disease. Using pinhole collimation and digital acquisition, a 50k count image of the thyroid was obtained 20 minutes after injection of 1mCi99m Tc-pertechnetate. Then a lmCi dose of Tl-201 chloride was injected and a series of images acquired for 30 minutes at 30 sec/image. Raw data was spatially filtered and normalized by summing sufficient T1-201 images to equal the Tc-99m image scale of maximum cts/pixel. Image subtraction (Tl-Tc) gave the final PT image. Of 10 pts who had previous neck exploration, all had PT pathology accurately localized by preoperative scanning (7=single adenoma, 2=single hyperplastic gland, 1=two hyperplastic glands). In two causes distant ectopic ...

1985-06-02

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

301

Telomerase-immortalized non-malignant human prostate epithelial cells retain the properties of multipotent stem cells

Small unilamellar vesicles which form when gel-state long-chain phosphatidylcholines are mixed with micellar short-chain lecithins undergo an increase in size as the long-chain species melts to its liquid-crystalline form. Analysis of the vesicle population with quasi-elastic light scattering shows that the particle size increases from 90-A radius to greater than 5000-A radius. Resonance energy transfer experiments show total mixing of lipid probes with unlabeled vesicles only when the Tm of the long-chain phosphatidylcholine is exceeded. This implies that the large size change represents a fusion process. Aqueous compartments are also mixed during this transition. 31P NMR analysis of the vesicle mixtures above the phase transition shows a great degree of heterogeneity with large unilamellar particles coexisting with oligo- and multilamellar structures. Upon cooling the vesicles below the Tm, the original size distribution (e.g., small unilamellar vesicles) is ...

1989-10-03

302

Synthesis, structural characterization, and performance evaluation of resorcinol-formaldehyde (R-F) ion-exchange resin

Understanding prostate stem cells may provide insight into the origin of prostate cancer. Primary cells have been cultured from human prostate tissue but they usually survive only 15-20 population doublings before undergoing senescence. We report here that RC-170N/h/clone 7 cells, a clonal cell line from hTERT-immortalized primary non-malignant tissue-derived human prostate epithelial cell line (RC170N/h), retain multipotent stem cell properties. The RC-170N/h/clone 7 cells expressed a human embryonic stem cell marker, Oct-4, and potential prostate epithelial stem cell markers, CD133, integrin #alpha#2#beta#1"h"i and CD44. The RC-170N/h/clone 7 cells proliferated in KGM and Dulbecco's Modified Eagle Medium with 10% fetal bovine serum and 5 #mu#g/ml insulin (DMEM + 10% FBS + Ins.) medium, and differentiated into epithelial stem cells that expressed epithelial cell markers, including CK5/14, CD44, p63 and cytokeratin 18 (CK18); as well as the mesenchymal cell ...

2008-01-01

303

Supramolecular Structures for Photochemical Energy Conversion

The 177 underground storage tanks at the DOE's Hanford Site contain an estimated 180 million tons of high-level radioactive wastes. It is desirable to remove and concentrate the highly radioactive fraction of the tank wastes for vitrification. Resorcinol-formaldehyde (R-F) resin, an organic ion-exchange resin with high selectivity and capacity for the cesium ion, which is a candidate ion-exchange material for use in remediation of tank wastes. The report includes information on the structure/function analysis of R-F resin and the synthetic factors that affect performance of the resin. CS-100, a commercially available phenol-formaldehyde (P-F) resin, and currently the baseline ion-exchanger for removal of cesium ion at Hanford, is compared with the R-F resin. The primary structural unit of the R-F resin was determined to consist of a 1,2,3,4-tetrasubstituted resorcinol ring unit while CS-100, was composed mainly of a 1,2,4-trisubstituted ring. CS-100 shows the presence of phenoxy-ether ...

2004-09-10

304

Structural, morphological and surface chemical features of Al{sub 2}O{sub 3} catalyst supports stabilized with CeO{sub 2}

OAK B188 The goal of this project is to mimic the energy transduction processes by which photosynthetic organisms harvest sunlight and convert it to forms of energy that are more easily used and stored. The results may lead to new technologies for solar energy harvesting based on the natural photosynthetic process. They may also enrich our understanding and control of photosynthesis in living organisms, and lead to methods for increasing natural biomass production, carbon dioxide removal, and oxygen generation. In our work to date, we have learned how to make synthetic antenna and reaction center molecules that absorb light and undergo photoinduced electron transfer to generate long-lived, energetic charge-separated states. We have assembled a prototype system in which artificial reaction centers are inserted into liposomes (artificial cell-like constructs), where they carry out light-driven transmembrane translocation of hydrogen ions to generate proton motive ...

2003-08-26

305

Steroidal hydrocarbons of the Kishenehn Formation, northwest Montana

Two families of CeO{sub 2}/Al{sub 2}O{sub 3} (ACE) catalyst supports, containing 3 and 20 % wt CeO{sub 2} respectively, have been examined and compared with the pure oxides CeO{sub 2} and (transition-phase) Al{sub 2}O{sub 3}. Structural data indicate that, also in the presence of CeO{sub 2}, the Al{sub 2}O{sub 3} support undergoes all phase transitions at the usual temperatures. Electron micrographs show that particles morphology and crystals size are mainly imposed by the Al{sub 2}O{sub 3} support. The porosimetric texture indicates a more pronounced meso-porosity in the ACE systems than in pure Al{sub 2}O{sub 3}, especially in the case of low CeO{sub 2} loadings. FTIR spectra and volumetric/calorimetric data of the adsorption of CO at {approx}300 K show that the surface Lewis acidity of aluminas is severely modified by the presence of CeO{sub 2}: the overall CO uptake is increased, there is the formation of one additional family of Lewis acid sites (Ce{sup 4+} ...

1995-12-31

306

The Oligocene Kishenehn Formation of northwest Montana and southeast British Columbia consists of fluvial and lacustrine sediments (marlstones, lignites and oil shales) deposited in an elongate, intermontane half-graben. The petroleum source rock potential and steroidal hydrocarbon distribution of selected shales of the Kishenehn Formation were examined. Several steroidal hydrocarbon series were documented, including 4-desmethylsteranes, 4-methylsteranes, sterenes, diasterenes, spirosterenes, C-ring monoaromatic steroids and B-ring monoaromatic anthrasteroids. Non-steroid hydrocarbons present include hopenes, ..beta beta..-hopanes, moretanes, perylene, botryococcane, a series of alkylcyclohexanes, and a fused-ring aromatic tentatively identified as a tetrahydrochrysene. Source rock analysis indicates that the Kishenehn Formation possesses excellent petroleum source potential. Conventional thermal maturity parameters, as well as maturity parameters derived from molecular parameters ...

1987-01-01

307

Should coronary angiography be the gold standard? A study correlating thallium myocardial scintigraphy, translesional pressure gradient and percent stenosis

Purpose: To conduct a retrospective analysis within a large university teaching hospital, comparing outcomes between patients receiving either radical surgery or radiotherapy as curative treatment for bladder cancer. Patients and Methods: Between March 1996 and December 2000, 169 patients were treated radically for muscle-invasive bladder cancer. Data were collected from patient notes. Statistical analyses were performed using Kaplan-Meier methods and Cox proportional hazards regression analysis to compare radiotherapy and surgical outcome data. Results: There was no difference in overall, cause-specific, and distant recurrence-free survival at 5 years between the two groups, despite the radiotherapy group being older (median age, 75.3 years vs. 68.2 years). There were 31 local bladder recurrences in the radiotherapy group (24 solitary), but there was no significant difference in distant recurrence-free survival. In a more recent (2002-2006) cohort, the median age of radiotherapy ...

2008-02-01

308

Session 1: Geothermal Pumping Systems and Two-Phase Flow Studies

Coronary angiography provides anatomical information whereas thellium myocardial scintigraphy measures resistive tissue perfusion. Because of this fundamental difference. The authors question the validity of using coronary angiography as the gold standard to judge thellium myocardial scintigraphy. The authors studied 20 patients undergoing elective percutaneous coronary angioplasty who fulfilled the following criteria: (1) history of chest pain; (2) angiographically significant single vessel disease (>50% stenosis); (3) no prior myocardial infarction. All patients underwent maximal exercise thallium single photon emission computed tomography (T1-SPECT). Tl-SPECT was scored visually according to a 0 to 3 scale (0=absent uptake; 1=markedly decreased uptake; 2=minimally decreased uptake; 3=normal uptake). Translesional gradient and percent stenosis were measured before and after angioplasty. The authors found that significant linear relationship exists between ...

1985-06-02

309

Role of E-cadherin in the induction of apoptosis of HPV16-positive CaSki cervical cancer cells during multicellular tumor spheroid formation.

Improvements in electric submersible pumping systems have resulted in a demonstrated downhole running life of one year for low horsepower units operating in 180 C brine. The implementation of a prototype pressurized lubrication system to prevent brine intrusion and loss of lubricating oil from the motor and protector sections has been successfully tested. Second generation pressurized lubrication systems have been designed and fabricated and will be utilized in downhole production pumping tests during FY84. Pumping system lifetime is currently limited by available power cable designs that are degraded by high-temperature brine. A prototype metal-sheathed power cable has been designed and fabricated and is currently undergoing destructive and nondestructive laboratory testing. This cable design has the potential for eliminating brine intrusion into the power delivery system through the use of a hermatically sealed cable from the surface to the downhole motor. The ...

1983-12-01

310

Reactive biomolecular divergence in genetically altered yeast cells and isolated mitochondria as measured by biocavity laser spectroscopy : a rapid diagnostic method for studying cellular responses to stress and disease.

Multicellular tumor spheroids (MCTS) are three dimensional cell culture systems induced by suspension culture. MCTS are widely used in cancer research because of their similarity to solid tumors. CaSki cells are derived from a metastatic cervical cancer containing human papillomavirus 16 (HPV16). Cell death of CaSki cells in MCTS has been previously reported, and our model is used to better characterize the mechanisms of cell death of HPV16-positive keratinocytes. In this study, we found that apoptosis of CaSki cells was induced by suspension culture along with the formation of MCTS after 24 h of incubation. In suspended CaSki cells, monoclonal antibodies blocking E-cadherin function inhibited MCTS formation and suppressed suspension-induced apoptosis in a dose-dependent manner. Western blot for E-cadherin detected upregulation of the authentic 120 kDa band from MCTS of CaSki cells as well as a shorter 100 kDa band. Addition of EGF, whose receptor is known to form a complex with ...

2008-01-01

311

Radiolytic stabilization of industrial poly(methyl methacrylate); Estabilizacao radiolitica do poli(metacrilato de metila) industrial

We report an analysis of four strains of baker's yeast (Saccharomyces cerevisiae) using biocavity laser spectroscopy. The four strains are grouped in two pairs (wild type and altered), in which one strain differs genetically at a single locus, affecting mitochondrial function. In one pair, the wild-type rho+ and a rho0 strain differ by complete removal of mitochondrial DNA (mtDNA). In the second pair, the wild-type rho+ and a rho- strain differ by knock-out of the nuclear gene encoding Cox4, an essential subunit of cytochrome c oxidase. The biocavity laser is used to measure the biophysical optic parameter Deltalambda, a laser wavelength shift relating to the optical density of cell or mitochondria that uniquely reflects its size and biomolecular composition. As such, Deltalambda is a powerful parameter that rapidly interrogates the biomolecular state of single cells and mitochondria. Wild-type cells and mitochondria produce Gaussian-like distributions with a single peak. In ...

2006-12-01

312

Radioguided occult lesion localization versus wire-guided localization for non-palpable breast lesions: randomized controlled trial

Poly(methyl methacrylate), PMMA, Acrigel, a Brazilian polymer, is used in the manufacture of medical supplies sterilisable by ionizing radiation. However, when PMMA is gamma-irradiated it undergoes main chain scissions, which promote molecular degradation causing reduction in its physical properties. Therefore, radiolytic stabilization of PMMA is important for to become it commercially radio sterilisable. In this work we investigated the radiolytic stabilization of PMMA by using HALS (Hindered Amine Light Stabilizer) additive, commercially used for photo and thermo oxidative stabilization of polymers. The investigation of the radiation-induced main chain scissions was carried out by viscometric method. The additive added to the polymer system at 0.3 % w/w promotes a molecular radioprotection of 61%. That means a reduction of G value (scissions/100 eV) from 2.6 to 1.0. In addition, the glassy transition temperature (Tg) of PMMA (no additive), significantly changed ...

2005-03-15

313

Scientific Electronic Library Online (English)

Abstract in english AIM: This prospective randomized clinical study was conducted to compare radioguided occult lesion localization (ROLL) with wire-guided localization to evaluate optimum localization techniques for non-palpable breast lesions. METHODS: A total of 108 patients who were undergoing an excisional biopsy for non-palpable breast lesions requiring pathologic diagnosis were randomly assigned to the ROLL group (n = 56) and wire-guided localization group (n = 52). In the study, pati (more) ents' characteristics, radiological abnormalities, radiological technique of localization, localization time, operation time, weight of the excised specimen, clearance margins, pathological diagnosis and perioperative complications were assessed. RESULTS: There were no differences between the two groups in terms of age, radiological abnormalities and localization technique (p = non-significant for all). ROLL techniques resulted in 100% retrieval of the lesions; for the ...

2011-01-01

314

Prospective benefit and effect of lipiodol marking in hepatocellular carcinoma; Moeglicher Nutzen und Auswirkung einer Lipiodolmarkierung auf die Histologie beim hepatozellulaeren Karzinom

Prompt fission neutron energy spectra induced by fast neutrons

Purpose: To assess the benefit and the effect of intraarterial lipiodol application on histological analysis of patients suspected of having HCC. To determine whether lipiodol marking leads to a better biopsy result and how lipiodol or a transarterial chemoembolization influences the histological diagnosis. Materials and Methods: Two groups of patients were examined. Group A included 14 patients highly suspected of having an HCC which had previously been unsuccessfully biopsied. A transarterial embolization with lipiodol was performed in these patients to mark intrahepatic tumors which could not otherwise be defined in unenhanced CT. A biopsy was then repeated. Group B included 22 patients undergoing therapy using transarterial chemoembolization (TACE). A biopsy was performed to support the diagnosis of a multifocal HCC before changing the therapy. Results: The transversal diameters of the biopsied tumors were similar in both groups (A: 22 mm; B: 21 mm). The length ...

2005-10-01

315

Prognostic factors in the treatment of Ewing's sarcoma

Prompt fission neutron energy spectra for "2"3"5U and "2"3"9Pu have been measured for fission neutron energies greater than the energy of the incident neutrons inducing fission. The measurements were undertaken to investigate the shape dependence of the fission neutron spectra upon both the incident neutron energy and the mass of the nucleus undergoing fission. Measurements were made for both nuclides at incident neutron energies of 0.50, 1.50, 2.50 and 3.50 MeV. The data are presented either as relative yields or as ratios of measured spectra to that of "2"3"5U at 0.50 MeV. Incident neutrons were produced by the "7Li(p,n)"7Be reaction using a pulsed, bunched proton beam from the 5.5 MV Van de Graaff accelerator at the University of Massachusetts Lowell Radiation Laboratory. Fission neutrons were detected by a thin liquid scintillator with good time resolution capabilities. Neutron energies were determined by time-of-flight techniques with pulse-shape ...

316

Products of the Benzene + O(3P) Reaction

From 1981 up to February 1985, a total of 93 protocol patients entered the study CESS 81. The protocol recommended an initial 18-week period of polychemotherapy (VACA) followed by local therapy and two additional cycles of chemotherapy. Local therapy consisted either of radical surgery or of incomplete resection plus postoperative irradiation with 36 Gy or of radiotherapy alone (46 and 60 Gy). Centrally located lesions were always irradiated with 60 Gy. This article summarizes the data after 5 years. Data of 93 patients were analysed in October 1986 after a median follow-up of 37 months. The projected 5-year survival is 50%. The relapse rate was 42%, distant relapses occurred in 19%, local (plus distant) relapses in 23%. Most of the relapses occurred during the first 3 years of observation. Failure rate was high in patients undergoing irradiation alone (44%). Initial tumour mass (> 100 ml) and histopathologic response to initial chemotherapy were identified as ...

317

Postremediation monitoring program baseline assessment report, Lower East Fork Poplar Creek, Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

The gas-phase reaction of benzene with O(3P) is of considerable interest for modeling of aromatic oxidation, and also because there exist fundamental questions concerning the prominence of intersystem crossing in the reaction. While its overall rate constant has been studied extensively, there are still significant uncertainties in the product distribution. The reaction proceeds mainly through the addition of the O atom to benzene, forming an initial triplet diradical adduct, which can either dissociate to form the phenoxy radical and H atom, or undergo intersystem crossing onto a singlet surface, followed by a multiplicity of internal isomerizations, leading to several possible reaction products. In this work, we examined the product branching ratios of the reaction between benzene and O(3P) over the temperature range of 300 to 1000 K and pressure range of 1 to 10 Torr. The reactions were initiated by pulsed-laser photolysis of NO2 in the presence of benzene and ...

2009-12-21

318

Physical mechanisms of transient enhanced dopant diffusion in ion-implanted silicon

Lower East Fork Poplar Creek (LEFPC) and its floodplain are contaminated with mercury (Hg) from ongoing and historical releases from the US Department of Energy (DOE) Oak Ridge Y-12 Plant. A remedial investigation and feasibility study of LEFPC resulted in the signing of a Record of Decision (ROD) in August 1995. In response to the ROD, soil contaminated with mercury above 400 mg/kg was removed from two sites in LEFPC and the floodplain during a recently completed remedial action (RA). The Postremediation Monitoring Program (PMP) outlined in the LEFPC Monitoring Plan was envisioned to occur in two phases: (1) a baseline assessment prior to remediation and (2) postremediation monitoring. The current report summarizes the results of the baseline assessment of soil, water, biota, and groundwater usage in LEFPC and its floodplain conducted in 1995 and 1996 by personnel of the Oak Ridge National Laboratory Biological Monitoring and Abatement Program (BMAP). This report also includes some ...

1998-04-01

319

Physical mechanisms of transient enhanced dopant diffusion in ion-implanted silicon

Implanted B and P dopants in Si exhibit transient enhanced diffusion (TED) during annealing which arises from the excess interstitials generated by the implant. In order to study the mechanisms of TED, transmission electron microscopy measurements of implantation damage were combined with B diffusion experiments using doping marker structures grown by molecular-beam epitaxy (MBE). Damage from nonamorphizing Si implants at doses ranging from 5{times}10{sup 12} to 1{times}10{sup 14}/cm{sup 2} evolves into a distribution of {l_brace}311{r_brace} interstitial agglomerates during the initial annealing stages at 670{endash}815{degree}C. The excess interstitial concentration contained in these defects roughly equals the implanted ion dose, an observation that is corroborated by atomistic Monte Carlo simulations of implantation and annealing processes. The injection of interstitials from the damage region involves the dissolution of {l_brace}311{r_brace} defects during Ostwald ripening with an ...

1997-05-01

320

Performance and exhaust emission characteristics of direct-injection diesel engine when operating on shale oil

Implanted B and P dopants in Si exhibit transient enhanced diffusion (TED) during annealing which arises from the excess interstitials generated by the implant. In order to study the mechanisms of TED, transmission electron microscopy measurements of implantation damage were combined with B diffusion experiments using doping marker structures grown by molecular-beam epitaxy (MBE). Damage from nonamorphizing Si implants at doses ranging from 5x10"1"2 to 1x10"1"4/cm"2 evolves into a distribution of #left brace#311#right brace# interstitial agglomerates during the initial annealing stages at 670 endash 815 degree C. The excess interstitial concentration contained in these defects roughly equals the implanted ion dose, an observation that is corroborated by atomistic Monte Carlo simulations of implantation and annealing processes. The injection of interstitials from the damage region involves the dissolution of #left brace#311#right brace# defects during Ostwald ripening with an activation ...

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

321

Noninvasive assessment of skin iron content in hemodialysis patients. An index of parenchymal tissue iron content

This article presents the comparative bench testing results of a naturally aspirated, four stroke, four cylinder, water cooled, direct injection Diesel engine when running on diesel fuel and shale oil that is produced in Estonia from local oil shale. The purpose of this research is to investigate the possibility of practical usage of the shale oil as the alternative fuel for a high speed Diesel engine as well as to evaluate the combustion efficiency, brake specific fuel consumption, emission composition changes and the smoke opacity of the exhausts. Test results show that when fuelling a fully loaded engine with shale oil, the brake specific fuel consumption at the maximum torque and rated power is correspondingly higher by 12.3% and 20.4%. However, the brake thermal efficiencies do not differ widely and their maximum values remain equal to 0.36-0.37 for Diesel fuel and 0.32-0.33 for shale oil. The total nitrogen oxide emissions from the shale oil at engine partial loads remain ...

2005-01-01

322

Non-seminomatous testicular germ cell tumours. Preliminary analysis of ongoing trials in the DATECA study

Iron overload has been described in patients undergoing chronic hemodialysis. The present study was undertaken to evaluate a rapid, noninvasive method for determination of skin iron by the technique of diagnostic x-ray spectrometry (DXS). Thirty-five patients receiving chronic hemodialysis treatment entered the study and were compared with 25 normal controls. Since pathological skin iron deposition occurs mainly at the dermal-epidermal junction in the basal cells of the epidermis, measurements were made in the thenar eminence representing mainly epidermal tissue (FeE), and in the forearm representative mainly of dermis (FeD). The mean +/- SD FeE iron concentrations were equivalent to 14.5 +/- 8.8 and 18.2 +/- 10.2 parts per million wet weight tissue (ppm) and both were significantly higher than in normal controls in which they averaged 9.2 +/- 2.5 ppm (P less than 0.005) and 10.2 +/- 3.2 ppm (P less than 0.001), respectively. There was significant positive ...

1988-07-01

323

Non-seminomatous testicular germ cell tumours

This report deals with the preliminary results of trials in the DATECA project with stage I, II and III patients with non-seminomatous germ cell tumours. Stage 1 patients were randomized between infradiaphragmatic irradiation and observation. No significant difference in recurrence rates has been observed as yet. Eighteen of 95 patients had recurrence with a median time to relapse of 3 months. Fifteen patients achieved complete remission after treatment by combination chemotherapy while 3 patients are still undergoing treatment. Stage II patients received 6 series of cis-platinum, bleomycin, and vinblastine. The patients were initially randomized to receive chemotherapy alone versus chemotherapy plus irradiation. Irradiation led to increased toxicity and decreased doses of the antineoplastic drugs. Fifty-one patients were studied. The overall complete remission rate was 89 per cent including 7 patients who achieved complete remission after secondary surgery. Three ...

1984-01-01

324

Nephrogenic systemic fibrosis after application of gadolinium-based contrast agents - a status paper; Nephrogene systemische Fibrose nach Anwendung gadoliniumhaltiger Kontrastmittel - ein Statuspapier zum aktuellen Stand des Wissens

This report deals with the preliminary results of trials in the DATECA project with stage I, II and III patients with non-seminomatous germ cell tumours. Stage 1 patients were randomized between infradiaphragmatic irradiation and observation. No significant difference in recurrence rates has been observed as yet. Eighteen of 95 patients had recurrence with a median time to relapse of 3 months. Fifteen patients achieved complete remission after treatment by combiantion chemotherapy while 3 patients are still undergoing treatment. Stage II patients received 6 series of cis-platinum, bleomycin, and vinblastine. The patients were initially randomized to receive chemotherapy alone versus chemotherapy plus irradiation. Irradiation led to increased toxicity and decreased doses of the antineoplastic drugs. Fifty-one patients were studied. The overall complete remission rate was 89 per cent including 7 patients who achieved complete remission after secondary surgery. Three ...

1984-01-01

325

Multiphase treatment of ODTX in HMX spheres

Recently the association of a rare disease named ''nephrogenic systemic fibrosis'' (NSF) with the administration of gadolinium-containing contrast media, especially gadodiamide (Omniscan, GE-Healthcare), was described. NSF is a scleroderma-like disease characterised by widespread tissue fibrosis. Until now, NSF cases were observed only in patients with kidney disease. Almost all patients were suffering from chronic renal insufficiency, 90 % of them required renal replacement therapy. The true incidence of the disease is unknown. First retrospective analyses of selected collectives of patients with end-stage renal disease showed 2 - 5 % cases of NSF after administration of Gadolinium-containing contrast agents with an odds ratio of 20 - 50 in comparison to non-exposed controls. NSF is a serious adverse reaction, which may result in severe disabilities and even death. Therefore all radiologists applying gadolinium-based contrast agents should be ...

2007-06-15

326

Metal Nanoparticles Preparation In Supercritical Carbon Dioxide Solutions

What will be discussed in this report represents a framework upon which multiphase and other real physical effects can be built. Chemical models of increasing complexity are envisioned and this methodology can provide a tool for evaluating new ideas against known experimental data. The recent work to be reported here addresses the multiphase issue of temperature deviation between phases undergoing chemical and heat transport processes. Modeling of the LLNL ODTX experiment will be performed with FLUENT, a commercially available computational fluid dynamics (CFD) code. FLUENT solves flows in 2D or 3D in Cartesian, cylindrical, or general curvilinear coordinates, with steady-state of fully time-dependent analysis. Multiphase flows in which two or more continuous phases are present can be solved with arbitrary volumetric sources of heat, mass, momentum, and chemical species applied through user-defined FORTRAN subroutines. FLUENT models these of phenomena by solving ...

1997-12-22

327

Mapping Strain in Nanocrystalline Nitinol: an X-ray Diffraction Method (SULI paper)

The novel optical, electronic, and/or magnetic properties of metal and semiconductor nanoparticles have resulted in extensive research on new methods for their preparation. An ideal preparation method would allow the particle size, size distribution, crystallinity, and particle shape to be easily controlled, and would be applicable to a wide variety of material systems. Numerous preparation methods have been reported, each with its inherent advantages and disadvantages; however, an ideal method has yet to emerge. The most widely applied methods for nanoparticle preparation include the sonochemical reduction of organometallic reagents,(1&2) the solvothermal method of Alivisatos,(3) reactions in microemulsions,(4-6) the polyol method (reduction by alcohols),(7-9) and the use of polymer and solgel materials as hosts.(10-13) In addition to these methods, there are a variety of methods that take advantage of the unique properties of a supercritical fluid.(14&15) Through simple ...

2004-04-01

328

Magnetic properties of Ni/sub 100-2x/Mn/sub x/Sb/sub x/-alloys (5less than or equal toxless than or equal to50) - solid and liquid state

Understanding the mechanical properties of biomedical devices is critical in predicting and preventing their failure in the body. Such knowledge is essential, for example, in the design of biomedical stents, which must undergo repeated strain over their ten year lifetimes without breaking. Computational models are used to predict mechanical response of a device, but these models are not complete; there are significant deviations from the predictions, especially when devices are subjected to repeated multi-axial loads. Improving these models requires comparisons with actual measurements of strained nitinol. Local measurements of the full strain tensor can be made using X-ray diffraction techniques, but they are currently limited to materials whose grain size is larger than the X-ray beam size or require several diffraction patterns produced by rotation of the sample. Nitinol stents are nanocrystalline, with grains smaller than any available X-ray beam. We present a ...

2006-01-04

329

Magnetic excitations in R_2PdSi_3 studied by inelastic neutron scattering

Magnetothermal measurements up to 1600 K have been made on alloys in the ternary Ni-Mn-Sb system with a constant ratio Mn/Sb=1/1, to which belong the two ferromagnetic Heusler phases Ni/sub 2/MnSb with L2/sub 1/ structure and NiMnSb with C1/sub b/ structure. The susceptibility-temperature curves show the constitution of the vertical section. At high temperatures the susceptibilities obey a Curie-Weiss law. In the solid state the effective magneton number decreases with increasing Mn concentration from 4.9 (Ni/sub 2/MnSb) to 3.8 (NiMnSb). Simultaneously, on the transition from Ni/sub 2/MnSb to NiMnSb there is a strong increase of the susceptibility and of the Curie temperature from 292 to 686 K. In the heterogeneous range between 10 and 20 at.% Mn another phase part appears which is ferromagnetic at room temperature. By a heat treatment it undergoes a distinct development. In the liquid phase, the alloys can be characterized by an extended Curie-Weiss law. Between ...

1989-02-01

330

Magnetic braking of collapsing interstellar clouds

R_2PdSi_3 compounds have been found to exhibit rich magnetic phenomena arising from the interplay between RKKY interaction, crystal electric field effects and geometric frustration due to the derived hexagonal AlB_2 structure. The observed crystallographic superstructure further complicates the CEF level scheme. Inelastic neutron scattering measurements on single crystals of Tm_2PdSi_3 and Er_2PdSi_3 have been performed at the cold triple axis spectrometer PANDA in FRM-II. Both compounds order antiferromagnetically at T_N=7 K and 2.1 K respectively; Er_2PdSi_3 undergoes a second phase transition at T_2=2 K. Several low lying CEF excitations (below 10 meV) were observed. The intensity of the lowest excitation show strong directional dependence (in HK0 plane for Er_2PdSi_3 and in HHL plane for Tm_2PdSi_3), from which the details of the transitional matrix could be deduced. Measurements in magnetic fields up to 13 T show Zeeman splitting of the CEF excitations. In ...

2009-03-22

331

Lifetime measurements of singlet ungerade states in isotopic molecular nitrogen

The purpose of this investigation is to show that resource to anisotropic compression along a magnetic field is not a necessary condition for star formation within large collapsing interstellar gas clouds. Although such a scenario would certainly eliminate the magnetic field and angular momentum problems associated with isotropically collapsing clouds, it is believed there is sufficient observational theoretical evidence to warrant the present study of magnetically braked, isotropically collapsing gas clouds. It is not attempted to disprove the hypothesis of anisotropic compression, but to offer instead, a reasonable alternative. Angular momentum transfer from magnetically braked, cool interstellar gas clouds of 10"2, 10"3 and 10"4 times the mass of the sun is examined. Magnetic torques acting on a contracting, rotating cloud, permeated by a frozen-in magnetic field coupling the cloud to the galactic field of the surrounding interstellar medium, produce kinks in the galactic field ...

332

Isoprenylation is required for the processing of the lamin A precursor

Full text: In the upper layers of the Earth's atmosphere, molecular nitrogen absorbs the extreme ultraviolet (XUV) solar radiation. The absorption is associated with dipole-allowed excitation of states of singlet ungerade symmetry ("1#SIGMA#"+_u and "1#PI#_u), which are known to undergo predissociation due to coupling with a mainfold of "1#PI#_u states. We determined new N_2 isotopic lifetimes of many "1#SIGMA#"+_u and "1#PI#_u states via line broadening measurements in the frequency domain. Ultrahigh resolution XUV + UV ionization spectra were recorded (bandwidth #approx# 250 MHz, resolving power 10"7), from which the natural linewidth, i.e. lifetime, was determined. These lifetimes provide new information about the predissociation of the singlet ungerade states in N_2. Tunable narrowband XUV radiation was produced by successively pulsed amplification of cw dye laser radiation, frequency doubling the pulsed visible laser beam into the UV and frequency tripling the ...

2004-07-19

333

Iodixanol in cerebral computed tomography: a randomized, double-blind, phase-III, parallel study with iodixanol and iohexol

The nuclear lamina proteins, prelamin A, lamin B, and a 70-kD lamina-associated protein, are posttranslationally modified by a metabolite derived from mevalonate. This modification can be inhibited by treatment with (3-R,S)-3-fluoromevalonate, demonstrating that it is isoprenoid in nature. We have examined the association between isoprenoid metabolism and processing of the lamin A precursor in human and hamster cells. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevinolin (lovastatin) specifically depletes endogenous isoprenoid pools and inhibits the conversion of prelamin A to lamin A. Prelamin A processing is also blocked by mevalonate starvation of Mev-1, a CHO cell line auxotrophic for mevalonate. Moreover, inhibition of prelamin A processing by mevinolin treatment is rapidly reversed by the addition of exogenous mevalonate. Processing of prelamin A is, therefore, dependent on isoprenoid metabolism. Analysis of the conversion of prelamin A to lamin A by two ...

1990-05-01

334

Investigating the formation mechanism of soot-like materials present in blast furnace coke samples

Iodixanol is a new nonionic dimer, isotonic with blood at all clinically relevant concentrations. Iodixanol (270 mg I/ml) was compared in a double-blind, randomized, parallel-group, phase-III study to the monomeric nonionic iohexol (300 mg I/ml) for evaluation of safety, tolerability and radiographic efficacy during cerebral CT. One hundred adult patients scheduled to undergo contrast-enhanced cerebral CT were randomly allocated to receive either iodixanol or iohexol. All completed the trial. Safety was evaluated by recording discomfort and other adverse events, tolerance by assessing intensity and incidence of discomfort. Radiographic efficacy was assessed from the diagnostic information and the radiographic density. No serious adverse events occurred. One patient (2 %) in the iodixanol group and one patient (2 %) in the iohexol group experienced a transient reddening at the neck and lower neck-line, respectively. Both contrast agents were well tolerated. One ...

1999-09-01

335

Inverse Bloch-oscillator: Strong Thz-photocurrent resonances at the Bloch frequency

An attempt to gain an understanding of the formation mechanism of these 'soot-like' materials has been made by means of tracing the changes in the molecular-mass distribution and molecular structure of the NMP-extractable materials from an injectant coal as well as its partially gasified chars and its pyrolytic tars. Variations in the SEC chromatograms provide clues about changes in the apparent molecular-mass distributions of these NMP extracts. Results suggest that the build-up of 'soot-like' materials follows from the secondary reactions of tars evolved from the injectant coal. The likely secondary-reaction pathways have been probed by collating structural information on these NMP extracts. The time-resolved 13-16 and 22-25 min elution fractions from the SEC column have been characterized using UV fluorescence (UV F) spectroscopy. Greater concentrations of larger aromatic ring systems are found present in samples formed under conditions appearing ...

2008-09-15

336

Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat

We have observed resonant changes in the current-voltage characteristics of miniband semiconductor superlattices when the Bloch frequency is resonant with a terahertz field and its harmonics: the inverse Bloch oscillator effect. The resonant feature consists of a peak in the current which grows with increasing laser intensity accompanied by a decrease of the current at the low bias side. The peak position moves linearly with the laser frequency. When the intensity is increased further the first peak starts to decrease and a second peak at about twice the voltage of the first peak is observed due to a two photon resonance. At the highest intensities we observe up to a four photon resonance. A superlattice is expected to show negative differential conductance due to the strong nonparabolicity of the miniband. In this situation the carriers should undergo Bloch oscillations with a frequency {omega}{sub B} = eEd/h. Transient Bloch oscillations of photo excited carriers ...

1995-12-31

337

Hydrogen embrittlement, revisited by in situ electrochemical nanoindentation

Paraquat (1,1'-dimethyl-4,4'-bipyridinium) is a widely used herbicide known to induce skin toxicity. This is thought to be due to oxidative stress resulting from the generation of cytotoxic reactive oxygen intermediates (ROI) during paraquat redox cycling. The skin contains a diverse array of antioxidant enzymes which protect against oxidative stress including superoxide dismutase (SOD), catalase, glutathione peroxidase-1 (GPx-1), heme oxygenase-1 (HO-1), metallothionein-2 (MT-2), and glutathione-S-transferases (GST). In the present studies we compared paraquat redox cycling in primary cultures of undifferentiated and differentiated mouse keratinocytes and determined if this was associated with oxidative stress and altered expression of antioxidant enzymes. We found that paraquat readily undergoes redox cycling in both undifferentiated and differentiated keratinocytes, generating superoxide anion and hydrogen peroxide as well as increased protein oxidation which ...

2008-09-15

338

High-mobility group box 1 release and redox regulation accompany regeneration and remodeling of skeletal muscle.

The fine scale mechanical probing capability of NI-AFM was used to examine hydrogen interaction with plasticity. To realize this, an electrochemical three electrode setup was incorporated into the NI-AFM. The developed ECNI-AFM is capable of performing nanoindentation as well as imaging surfaces inside electrolytes. The developed ECNI-AFM setup was used to examine the effect of cathodically charged hydrogen on dislocation nucleation in pure metals and alloys. It was shown that hydrogen reduces the pop-in load in all of the tested materials except Cu. The reduced pop-in load can be interpreted as the HELP mechanism. Classical dislocation theory was used to model the homogeneous dislocation nucleation and it was shown that H reduces the activation energy for dislocation nucleation in H sensitive metals which are not undergoing a phase transformation. The activation energy for dislocation nucleation is related to the material specific parameters; shear modulus {mu}, ...

2007-07-01

339

High strain rate properties of composites

Abstract High-mobility group box 1 (HMGB1), a damage-associated molecular pattern (DAMP) molecules, favors tissue regeneration via recruitment and activation of leukocytes and stem cells. Here we demonstrate, in a model of acute sterile muscle injury, that regeneration is accompanied by active reactive oxygen species (ROS) production counterbalanced and overcome by the generation of antioxidant moieties. Mitochondria are initially responsible for ROS formation. However, they undergo rapid disruption with almost complete disappearance. Twenty-four hours after injury, we observed a strong induction of MURF1 and atrogin-1 ubiquitin ligases, key signals in activation of the proteasome system and induction of muscle atrophy. At later time points, ROS generation is maintained by nonmitochondrial sources. The antioxidant response occurs in both regenerating fibers and leukocytes that express high levels of free thiols and antioxidant enzymes, such as superoxide dismutase ...

2011-05-09

340

Polymer matrix composites are presently used in many fields due to their excellent mechanical properties such as high specific strength and stiffness. However, not much is known of these composites' response to impact loading, which usually occurs at strain rates much higher than the strain rates used to measure the quasi-static mechanical properties of materials. The use of static properties in the study of structures that undergo dynamic loading can produce excessive design weight or cause unexplained and untimely failure. The studies included in this dissertation provide the results of Split Hopkinson Pressure Bar experiments to determine the ultimate compressive strength and strain of composites at high strain rates. Most researchers are using specimens with different dimensions and geometry. For this reason, it is difficult to compare results of tests done by different people. Herein, the Split Hopkinson Pressure Bar facility at the University of Delaware is ...

1998-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

341

Getting gas to shore

Fundamental studies of coal liquefaction

Calls for containers to transport compressed natural gas, and a ship or barge to house some 200 employees in the Terra Nova offshore oilfield while the oil field's floating production, storage and offloading (FPSO) system is undergoing a major overhaul, are attracting attention on Canada's east coast offshore oilpatch. The FPSO is located offshore, 350 km east of St. John's, Newfoundland. Petro-Canada, operators of the FPSO anticipate that by having all required personnel nearby, the total shutdown time for the overhaul could be minimized. The CNG container was designed by Trans Ocean Gas Inc. in response to an invitation by Husky Oil and Petro-Canada, the White Rose field partners. Trans Ocean Gas strongly believes that CNG will become the technology of choice for getting natural gas ashore and to markets from stranded hydrocarbon pools in Atlantic Canada and the rest of the world where pipeline systems would be too expensive to build ...

2004-10-01

342

Functions of mammalian Cdc7 kinase in initiation/monitoring of DNA replication and development

The authors have examined the pyrolysis of Argonne samples of Wyodak and Illinois No. 6 coal in argon, undecane, Tetralin, and water. The effects of the pyrolysis on individual particles of coal were monitored visually in a cell with diamond windows capable of operation to temperature and pressures in excess of 500{degrees}C and 3000 psi. The changes in the particles from ambient to 460{degrees}C were recorded in real time on video tape, and images were then taken from the tape record and analyzed. The study showed that in argon both coals developed tars at 350{degrees}-370{degrees}C. The tars then quickly evaporated, leaving core particles remarkably similar in size and shape to the initial particles. These observations suggest that coal does not melt nor become fully liquid when heated. Nor does the softened coal undergo crosslinking to generate coke. Rather the simple loss of volatiles leaves behind the core residue as coke. Contrary to the common view, there ...

1995-01-01

343

Functional Characterization of Melanocyte Stem Cells in Hair Follicles.

Cdc7 kinase plays an essential role in firing of replication origins by phosphorylating components of the replication complexes. Cdc7 kinase has also been implicated in S phase checkpoint signaling downstream of the ATR and Chk1 kinases. Inactivation of Cdc7 in yeast results in arrest of cell growth with 1C DNA content after completion of the ongoing DNA replication. In contrast, conditional inactivation of Cdc7 in undifferentiated mouse embryonic stem (ES) cells leads to growth arrest with rapid cessation of DNA synthesis, suggesting requirement of Cdc7 functions for continuation of ongoing DNA synthesis. Furthermore, loss of Cdc7 function induces recombinational repair (nuclear Rad51 foci) and G2/M checkpoint responses (inhibition of Cdc2 kinase). Eventually, p53 becomes highly activated and the cells undergo massive p53-dependent apoptosis. Thus, defective origin activation in mammalian cells can generate DNA replication checkpoint signals. Efficient removal of ...

2003-11-27

344

Fatigue behavior of Alloy 690 and Alloy 800 SG tubing at temperatures up to 330{sup o}C in very high cycle fatigue regime

In mice, coat pigmentation requires a stem cell (SC) system in which the survival, proliferation, and differentiation of melanocytes (MCs) are regulated by microenvironments in hair follicles (HFs). In vitro systems are required to analyze the behavior of single melanocyte stem cells (MCSCs) and their potential to form SC systems in vivo. We describe here an experimental system for the isolation, self-renewal, and differentiation of MCSCs, as well as an in vivo reconstitution assay for assessing their potential. Using Dct(tm1(Cre)Bee)/CAG-CAT-GFP mice, we show that, in the presence of stem cell factor and basic fibroblast growth factor and the XB2 feeder cell line, purified MCSCs can undergo clonogenic proliferation, resulting in c-Kit(low) side scatter(low) cells. In culture, these cells maintain their capacity to differentiate and reconstitute an MCSC system in HFs. As these cells are present in the upper part of the HF near the bulge region, express only low ...

2011-07-14

345

Fatigue behavior of Alloy 690 and Alloy 800 SG tubing at temperatures up to 330"oC in very high cycle fatigue regime

During the service in nuclear power plants, steam generator (SG) tubing will suffer from a vibration with a frequency from 30-40 Hz. This means that SG tubing will undergo a very high cycle fatigue process during the design life time (25 years=about 3x10{sup 10}cycles). The material degradation and the very high cycle fatigue life of SG tubing materials due to the vibration are therefore of concern. In this investigation, the fatigue properties of Alloy 690 and Alloy 800 SG tubing in the very high cycle fatigue regime (higher than 10{sup 7} cycles) and strain controlled fatigue at temperatures up to 330{sup o}C have been investigated. The fatigue properties of SG tubing of Alloy 690 are comparable to that of wrought material. The strain controlled fatigue properties of Alloy 690 and Alloy 800 are slightly better at 288{sup o}C than at room temperature (RT). At the stress near the fatigue endurance, the influence of temperature on the high cycle fatigue properties ...

2007-07-01

346

Experimental and clinical studies on the usefulness and assessment of the angiographic images processed by a digital radiography system (FCR: Fuji Computed Tomography)

During the service in nuclear power plants, steam generator (SG) tubing will suffer from a vibration with a frequency from 30-40 Hz. This means that SG tubing will undergo a very high cycle fatigue process during the design life time (25 years=about 3x10"1"0cycles). The material degradation and the very high cycle fatigue life of SG tubing materials due to the vibration are therefore of concern. In this investigation, the fatigue properties of Alloy 690 and Alloy 800 SG tubing in the very high cycle fatigue regime (higher than 10"7 cycles) and strain controlled fatigue at temperatures up to 330"oC have been investigated. The fatigue properties of SG tubing of Alloy 690 are comparable to that of wrought material. The strain controlled fatigue properties of Alloy 690 and Alloy 800 are slightly better at 288"oC than at room temperature (RT). At the stress near the fatigue endurance, the influence of temperature on the high cycle fatigue properties of Alloy 690 is ...

2007-08-19

347

Experimental and clinical studies on the usefulness and assessment of the angiographic images processed by a digital radiography system (FCR: Fuji Computed Tomography)

The purpose of this study was to assess experimentally and clinically the usefulness of Fuji Computed Radiography (FCR) in angiographic examinations. FCR had a spatial resolution with much lower X-ray exposure doses, although the resolution of FCR was generally inferior to conventional films. When a contrast medium of 1% iodine concentration was used, FCR pinpointed a mass 1.5 mm in diameter; and conventional film could detect a mass 2.2 mm in diameter. The contrast of iodine in FCR examinations was stable. A high sensitivity of imaging plate allowed a wide range of visualization. In 148 selective angiographic examinatinons for 138 patients, FCR-subtraction images were superior to conventional film angiography for contrast resolution; it had a high sensitivity in detecting areas, such as the mediastimun and left lobe of the liver, and tumor stains in capillary phase. The capability of FCR arteriogram was as good as film arteriogram even with a half concentration of contrast medium and ...

1989-06-01

348

Electric utilities in 2007

The purpose of this study was to assess experimentally and clinically the usefulness of Fuji Computed Radiography (FCR) in angiographic examinations. FCR had a spatial resolution with much lower X-ray exposure doses, although the resolution of FCR was generally inferior to conventional films. When a contrast medium of 1% iodine concentration was used, FCR pinpointed a mass 1.5 mm in diameter; and conventional film could detect a mass 2.2 mm in diameter. The contrast of iodine in FCR examinations was stable. A high sensitivity of imaging plate allowed a wide range of visualization. In 148 selective angiographic examinatinons for 138 patients, FCR-subtraction images were superior to conventional film angiography for contrast resolution; it had a high sensitivity in detecting areas, such as the mediastimun and left lobe of the liver, and tumor stains in capillary phase. The capability of FCR arteriogram was as good as film arteriogram even with a half concentration of contrast medium and ...

1989-01-01

349

Effects of postoperative adjuvant chemotherapy and radiotherapy on ovarian function in women undergoing treatment for soft tissue sarcoma

A century ago--in the year J.J. Thomson discovered the electron--electricity, gas and traction companies battled for markets, and corrupt city councils demanded their fair share of the take. One tycoon became so disgusted with the confusion and dishonesty that he decided to bribe the legislature to set up an honest, state-run regulatory agency that would bring order to chaos. But he was found out. The scandal set back the cause of regulation until 1907, the year in which the electric washing machine and the vacuum cleaner were invented. By then, electricity sales had septupled from 1897 levels, and three states had established utility regulation. In the coming decade, 1997 to 2007, the utility business could undergo similar dramatic change, but it will move toward less regulation and more competition during a period of slow growth. Management will have to work harder to achieve success, however, because much of the profits will have to come not from a growing ...

1998-10-01

350

Effects of postoperative adjuvant chemotherapy and radiotherapy on ovarian function in women undergoing treatment for soft tissue sarcoma

Ovarian function was evaluated in 11 women 16 to 43 years of age at treatment who received doxorubicin, cyclophosphamide, and high doses of methotrexate with or without radiotherapy in adjuvant therapy of soft tissue sarcoma. Five women (16-33 yr old) who received chemotherapy alone or combined with radiotherapy only at sites distant from the ovaries (chest wall, thigh, and leg) had minimal menstrual irregularities or temporary cessation of menses during therapy; cyclic menses returned promptly after therapy. Gonadotropin levels (expressed as means +/- SD) (follicle-stimulating hormone (FSH), 10 +/- 15 mlU/ml; luteinizing hormone (LH), 10 +/- 4 mlU/ml) and 17 ..beta..-estradiol (E/sub 2/) levels (means +/- SD, 208 +/- 147 pg/ml) were normal. By contrast, 4 older women (ages 36-43 yr) who received similar treatment developd persistent amenorrhea with postmenopausal levels of gonadotropin (FSH, 109 +/- 29 mlU/ml; LH, 72 +/- 19 mlU/ml) and E/sub 2/ (19 +/- 8 pg/ml). Two additional women ...

1981-12-01

351

Effects of acid mine drainage on a headwater stream ecosystem in Colorado

Ovarian function was evaluated in 11 women 16 to 43 years of age at treatment who received doxorubicin, cyclophosphamide, and high doses of methotrexate with or without radiotherapy in adjuvant therapy of soft tissue sarcoma. Five women (16-33 yr old) who received chemotherapy alone or combined with radiotherapy only at sites distant from the ovaries (chest wall, thigh, and leg) had minimal menstrual irregularities or temporary cessation of menses during therapy; cyclic menses returned promptly after therapy. Gonadotropin levels (expressed as means +/- SD (follicle-stimulating hormone (FSH), 10 +/- 5 mlU/ml; luteinizing hormone (LH), 10 +/- 4 mlU/ml) and 17 beta-estradiol (E2) levels (means +/- SD, 208 +/- 147 pg/ml) were normal. By contrast, 4 older women (ages 36-43 yr) who received similar treatment developed persistent amenorrhea with postmenopausal levels of gonadotropin (FSH, 108 +/- 29 mlU/ml; LH, 72 +/- 19 mlU/ml) and E2 (19 +/- 8 pg/ml). Two additional women (ages 21 and 39 ...

1981-12-01

352

Effective dose estimation in whole-body multislice CT in paediatric trauma patients

The ecological effects of acid mine drainage were investigated during the summer of 1993 on St. Kevin Gulch, a headwater stream near Leadville, Colorado. The stream currently receives acidic water from an abandoned mine. The pH downstream of the mine is between 3.5 and 4.5, and several metals exceed concentrations toxic to aquatic organisms. Zinc is present at especially high concentrations (1 to 10 mg/L) Furthermore, the stream bottom is covered with a thick layer of iron hydroxide precipitates. Effects on stream biota have been dramatic. Aquatic flora in the affected reach is limited to a green filamentous alga, Ulothrix subtilissima. Macroinvertebrate densities are significantly lower in the affected reach (mean = 99 indiv/m"2; SD = 88 indiv/M"2) compared to an upstream (pristine) reference reach (mean = 1,735 indiv/m"2; SD = 652 indiv/M"2). Functional processes were also studied in the stream. Net primary production (NPP) was measured during midday with recirculating chambers. ...

353

Double-blind trial of the efficacy of pentoxifylline vs thalidomide for the treatment of type II reaction in leprosy

The number of multislice CT (MSCT) scans performed in polytraumatized children has increased rapidly. There is growing concern regarding the radiation dose in MSCT and its long-term consequences, especially in children. To determine the effective dose to polytraumatized children who undergo whole-body MSCT. A total of 51 traumatized children aged 0-16 years underwent a polytrauma protocol CT scan between November 2004 and August 2006 at our institution. The effective dose was calculated retrospectively by a computer program (CT-Expo 1.5, Hannover, Germany). The mean effective dose was 20.8 mSv (range 8.6-48.9 mSv, SD{+-}7.9 mSv). There was no statistically significant difference in the effective dose between male and female patients. Whole-body MSCT is a superior diagnostic tool in polytraumatized children with 20.8 mSv per patient being a justified mean effective dose. In a potentially life-threatening situation whole-body MSCT provides the clinicians with ...

2009-03-15

354

Scientific Electronic Library Online (English)

Abstract in english Type II reaction in leprosy, or erythema nodosum leprosum (ENL), is often characterized by severe clinical symptoms together with nerve function impairment leading to permanent disabilities. Thalidomide has been shown to be a highly effective drug for the treatment of ENL. It is, however, contraindicated for women of childbearing age due to its teratogenicity. On the other hand, pentoxifylline, used to treat hypercoagulable states, is not teratogenic and, like thalidomide (more) , can inhibit the synthesis of tumor necrosis factor-a and other cytokines. In the present randomized double-blind clinical study we compared the effectiveness of orally administered pentoxifylline vs thalidomide in treating type II reaction in 44 patients. Daily doses of 300 mg thalidomide or 1.2 g pentoxifylline were administered for 30 days to multibacillary leprosy patients undergoing type II reaction. Randomly chosen patients were included in the study before, ...

2007-02-01

355

Digital atlas of fetal brain MRI

Diagnostic imaging of Thorotrast associated cholangiocarcinoma and mixed hepatocellular and cholangiocellular carcinoma

Fetal MRI can be performed in the second and third trimesters. During this time, the fetal brain undergoes profound structural changes. Interpretation of appropriate development might require comparison with normal age-based models. Consultation of a hard-copy atlas is limited by the inability to compare multiple ages simultaneously. To provide images of normal fetal brains from weeks 18 through 37 in a digital format that can be reviewed interactively. This will facilitate recognition of abnormal brain development. T2-W images for the atlas were obtained from fetal MR studies of normal brains scanned for other indications from 2005 to 2007. Images were oriented in standard axial, coronal and sagittal projections, with laterality established by situs. Gestational age was determined by last menstrual period, earliest US measurements and sonogram performed on the same day as the MR. The software program used for viewing the atlas, written in C, permits linked ...

2010-02-01

356

Determination of the helium diffusion coefficient in nuclear waste storage ceramics by a nuclear reaction analysis method

Computed tomography would be a better method to detect and characterize a Thorotrast-induced liver tumour. The selective opacification of the RES by Thorotrast creates an intrinsic opacification of the liver similar in effect to contrast agents being evaluated for liver CT, such as ethoioidized oil emulsion. The computed tomographic appearance of Thorotrast-associated cholangiocarcinoma is usually a large, inhomogenous mass composed of disordered area of tissue of high density due to Thorotrast deposits, and of very low density. Thorotrast-induced cholangiocarcinoma originates in the peripheral biliary tree suprounding the highest mean concentration of Thorotrast deposition, so that visible soft tissue masses in the higher density spots in the liver are not produced in the early stage. The tendency for the opacity of the liver to decrease slowly with time and result in an uneven trabeculation and high density spots suggests that small tumors may be difficult to detect againist such an ...

357

Dendroaspis natriuretic peptide and the designer natriuretic peptide, CD-NP, are resistant to proteolytic inactivation.

Host matrices for actinide immobilisation will undergo the formation of large helium quantities due to alpha decay. Helium diffusion rate has to be known in order to predict the long-term behaviour of the material, and particularly, the influence of helium accumulation on mechanical properties. A nuclear reaction analysis method, namely the "3He(d, p)"4He reaction, has been used to analyse the evolution of "3He profiles after ion implantations at 1 and 3 MeV in two materials, monoclinic ZrO_2 (as a test material) and Ca_9Nd(PO_4)_5(SiO_4)F_1_._5(OH)_0_._5 britholite (envisaged for Am and Pu long-term storage). Two data processing methods are used: the classical excitation curve (proton yields versus deuteron energy) and second, the proton energy spectrum for a given deuteron energy. The characteristics of the "3He profiles (depth, width) obtained by both methods are compared to SRIM estimations. Their evolution during subsequent annealings allows an estimation of ...

2002-06-01

358

Daily cone-beam computed tomography used to determine tumour shrinkage and localisation in lung cancer patients

Designer natriuretic peptides (NPs) represent an active area of drug development. In canine and human studies, the designer natriuretic peptide CD-NP demonstrated more desirable therapeutic potential than recombinant B-type NP (BNP), which is known as nesiritide and is approved for treatment of acute decompensated heart failure. However, why CD-NP is more effective than BNP is not known. We previously reported that CD-NP is a poorer activator of human guanylyl cyclase-A (GC-A) and a better activator of human guanylyl cyclase-B than BNP. Here, guanylyl cyclase bioassays were used to compare the susceptibility of CD-NP verses ANP, BNP, CNP and DNP to inactivation by human kidney membranes. The half time (t(1/2)) for CD-NP inactivation was increased by factors of 13, 3 and 4 compared to ANP, BNP and CNP, respectively, when measured in the same assay. Surprisingly, DNP failed to undergo complete inactivation and was the most degradation resistant of the peptides ...

2011-04-01

359

Current Status on Stress Diagnostic Kit and Detection Technology

Purpose/Objective. Daily Cone-beam computed tomography (CBCT) in room imaging is used to determine tumour shrinkage during a full radiotherapy (RT) course. In addition, relative interfractional tumour and lymph node motion is determined for each RT fraction. Material and methods. From November 2009 to March 2010, 20 consecutive lung cancer patients (14 NSCLC, 6 SCLC) were followed with daily CBCT during RT. The gross tumour volume for lung tumour (GTV-t) was visible in all daily CBCT scans and was delineated at the beginning, at the tenth and the 20th fraction, and at the end of treatment. Whenever visible, the gross tumour volume for lymph nodes (GTV-n) was also delineated. The GTV-t and GTV-n volumes were determined. All patients were setup according to an online bony anatomy match. Retrospectively, matching based on the internal target volume (ITV), the GTV-t or the GTV-n was performed. Results. In eight patients, we observed a significant GTV-t shrinkage (15-40%) from the planning ...

2010-10-15

360

Creep and fatigue of alloy 800 in helium

The accurate measurement of a stress level is one of the most important issues in a stress diagnosis and its measurement could be of great value in clinical medicine. Stress has a potent effect on the spirit and physical condition of an individual. There are various methods available for its measurement. Some of the commonly used techniques for the diagnosis of a stress level include analysis of the body fluids, questionnaire assessments, psychophysiological evaluations and by determining heart rate variability (HRV) of subjects. However, the existing diagnostic methods have several defects like, a low sensitivity, inaccuracy and long of operation time. In this report, we present a diagnostic technology to detect a stress level which is the origin of various diseases. This method can be of great help in providing an early diagnosis through a biosensor and might play a vital role in preventing diseases like hypochondria and hypertension. Majority of the human population is exposed to ...

2008-06-15

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361

Correlating microstructure and thermal transport of irradiated SiC

Proposals for use of Alloy 800 as a H.T.R. boiler material have prompted studies of its creep and high temperature fatigue properties in impure helium with comparative tests in air. In impure helium, as expected in a H.T.R., reactions of potential importance are selective oxidation (of chromium, aluminium and titanium) and possibly carburisation from carbon monoxide or methane. In air, general oxidation will occur, possibly accompanied by nitridation. The effects of these reactions will depend on specimen geometry and the nature of the deformation. Two important possibilities are: (i) that environment affects the structure and properties of a surface zone of material undegoing uniform deformation (this may modify creep rate and crack nucleation); and (ii) that environment affects behaviour of a small region (e.g. at the root of a notch or ahead of a crack) in a specimen undergoing non-uniform deformation (this will modify crack growth and hence rupture life or ...

362

Concurrent Chemoradiotherapy in Resected Extrahepatic Cholangiocarcinoma

Full text of publication follows: The effect of neutron irradiation on the thermal conductivity of silicon carbide can be dramatic depending on the irradiation temperature and fluence the material is subjected to, and may be a critical factor defining it's use in fusion systems. Historically there have been several papers describing the effect of neutron irradiation on thermal conductivity degradation of SiC, predominately in the low to intermediate temperature ranges. Practically all of this work has been at temperatures lower than the application temperature for SiC being considered by the conceptual fusion reactors. This paper provides new data on the thermal conductivity of high quality CVD silicon carbide irradiated in a range of doses and temperature spanning the proposed fusion reactor temperature range. Specifically, an irradiation was carried out from fractions milli-dpa to approximately 8 dpa in the HFIR with irradiation temperatures ranging from 80-1600 deg. C. Results of ...

2007-12-10

363

Composition, structure and evolution of neutron stars with kaon condensates

Purpose: Extrahepatic cholangiocarcinoma is a rare malignancy. Despite radical resection, survival remains poor, with high rates of local and distant failure. To clarify the role of radiotherapy with chemotherapy, we performed a retrospective analysis of resected patients who had undergone chemoradiotherapy. Methods and Materials: A total of 45 patients (13 with proximal and 32 with distal disease) underwent resection plus radiotherapy (median dose, 50.4 Gy). All but 1 patient received concurrent fluoropyrimidine-based chemotherapy. The median follow-up was 30 months for all patients and 40 months for survivors. Results: Of the 45 patients, 33 underwent adjuvant radiotherapy, and 12 were treated neoadjuvantly. The 5-year actuarial overall survival, disease-free survival, metastasis-free survival, and locoregional control rates were 33%, 37%, 42%, and 78%, respectively. The median survival was 34 months. No patient died perioperatively. Patient age #<=#60 years and perineural ...

2009-01-01

364

Combination of admixtures to improve the robustness of high-volume fly ash concrete in hot weather[ACI SP-239

We investigate the possibility of kaon condensation in the dense interior of neutron stars through the s-wave interaction of kaons with nucleons. We include nucleon-nucleon interactions by using simple parametrizations of realistic forces, and include electrons and muons in #beta#-equilibrium. The equation of state above the condensate threshold is derived in the mean field approximation. The conditions under which kaon condensed cores undergo a transition to quark matter containing strange quarks are also established.The critical density for kaon condensation lies in the range (2.3-5.0)#rho#_0, where #rho#_0=0.16 fm"-"3 is the equilibrium density of nuclear matter. The critical density depends largely on the value of the strangeness content of the proton, the size of which is controversial. For too large a value of the strangeness content, matter with a kaon condensate is not sufficiently stiff to support the lower limit of 1.44 M_o_e_d_o_t for a neutron star. ...

365

Can simulation measurements be used to predict the irradiated lung volume in the tangential fields in patients treated for breast cancer

A precise admixtures system is needed when using high-volume fly ash concrete as fresh concrete occasionally undergoes rapid slump loss after mixing, which can cause problems with casting, pumping and finishing of the concrete in hot weather. This paper provided details of a study conducted to implement high-volume fly ash concrete technology in India. Different families of admixtures were investigated to determine their water reduction capacities. A set-retarding admixture was used in some of the concrete mixtures in order to determine its efficacy. An Indian Portland cement was used to create a total of 22 different concrete mixtures. Four different fly ashes were used to replace portions of the concrete. The slump of the fresh concrete mixture was monitored for 2 to 3 hours. Unit weight and temperature of the concrete was measured. Specimens were cast in steel moulds in order to determine the compressive strength and unit weight of the hardened concrete. The ...

2006-07-01

366

Asymptomatic cholelithiasis: is cholecystectomy really needed? A critical reappraisal 15 years after the introduction of laparoscopic cholecystectomy.

A simple method of estimating the amount of lung irradiated in patients with breast cancer would be of use in minimizing lung complications. To determine whether simple measurements taken at the time of simulation can be used to predict the lung volume in the radiation field, we performed CT scans as part of treatment planning in 40 cases undergoing radiotherapy for breast cancer. Parameters measured from simulator films included: (a) the perpendicular distance from the posterior tangential field edge to the posterior part of the anterior chest wall at the center of the field (CLD); (b) the maximum perpendicular distance from the posterior tangential field edge to the posterior part of the anterior chest wall (MLD); and (c) the length of lung (L) as measured at the posterior tangential field edge on the simulator film. CT scans of the chest were performed with the patient in the treatment position with 1 cm slice intervals, covering lung apex to base. The ...

1990-01-01

367

An analysis on the mid-latitude scintillation and coherence frequency bandwidth using transionospheric VHF signals

Asymptomatic cholelithiasis is increasingly diagnosed today, mainly as a result of the widespread use of abdominal ultrasonography for the evaluation of patients for unrelated or vague abdominal complaints. About 10-20% of people in most western countries have gallstones, and among them 50-70% are asymptomatic at the time of diagnosis. Asymptomatic gallstone disease has a benign natural course; the progression of asymptomatic to symptomatic disease is relatively low, ranging from 10-25%. The majority of patients rarely develop gallstone-related complications without first having at least one episode of biliary pain ("colic"). In the prelaparoscopy era, (open) cholecystectomy was generally performed for symptomatic disease. The minimally invasive laparoscopic cholecystectomy refueled the discussion about the optimal management of asymptomatic cholelithiasis. Despite some controversy, most authors agree that the vast majority of subjects should be managed by observation alone (expectant ...

2007-03-28

368

Acid/base and hydrogen bonding effects on the proton-coupled electron transfer of quinones and hydroquinones in acetonitrile: Mechanistic investigation by voltammetry, "1H NMR and computation

An analysis was perfonned on the mid-latitude scintillation and coherence frequency bandwidth (Fcoh) using transionospheric VHF signal data. The data include 1062 events spanning from November 1997 to June 2002. Each event records FORTE satellite received VHF signals from LAPP located at Los Alamos, New Mexico. Fcohs were derived to study scintillation characteristics on diurnal and seasonal variations, as well as changes due to solar and geomagnetic activities. Comparisons to the VHFIUHF coherence frequency bandwidth studies previously reported at equatorial and mid-latitude regions are made using a 4th power frequency dependence relationship. Furthennore, a wideband ionospheric scintillation model, WBMOD, was used to estimate Fcohs and compared with our VHF Fcoh values. Our analysis indicates mid-latitude scintillation characteristics that are not previously revealed. At the VHF bottom frequency range (3035 MHz), distinguished smaller Fcohs are found in time period from sunset to ...

2008-01-01

369

A zwitterionic silylene as reactive intermediate and its unusual dimerization to an N-heterobicyclic disilane.

This report seeks to address the role of hydrogen bonding with Bronsted acids and bases in proton-coupled electron transfer (PCET) as it pertains to concerted or stepwise pathways of quinone (Q) and hydroquinone (QH_2) electrochemistry. This study was performed using a series of techniques that included cyclic voltammetry (CV), digital simulations, computational chemistry and "1H NMR. Hydrogen bonding was inferred by a decrease in diffusion coefficient (D) values measured using a pulsed gradient echo- (PGE-) "1H NMR technique. Changes of 40.8% and 37.9% in D values were only noted after the addition of two equivalents of acetate to 1,4-hydroquinone (1,4-QH_2) and catechol (1,2-QH_2), respectively. In contrast, the D values for the addition of selected amines (pyridine, N,N-diisopropylethylamine and triethylamine) changed only 3.2% on average. Quantum mechanical calculations were conducted to determine the pK_a of all quinoid species to serve as a starting point for the determination of ...

2010-09-01

370

A study on the mineral density of the lumbar vertebral bone in children of metabolic disorders and control using single energy quantitative CT

A way to synthesize the transient zwitterionic silylene L'Si: 8 {L'=CH[(C=CH(2))CMe(N(tBu))(2)]} and achieve its facile dimerization to the remarkable N-heterobicyclic disilane 8(2) is described. At first, employing the beta-diketiminate ligand L [L=CH(CMeN(tBu))(2)], both starting materials LH (2) and its N-lithium salt LLi (3) can react with SiBr(4) to yield the silylene precursor L'SiBr(2) (4) by silicon-induced C-H activation at an exocyclic methyl group on the backbone of the ligand. Compound 4 reacts with SiBr(4) above room temperature to afford the unexpected terminal CH(SiBr(3))-substituted dibromosilane 6 along with the unique tricyclic trisilane 7. Reduction of 4 with KC(8) at 0 degrees C furnishes the novel N-heterobicyclic disilane 8(2), which is a formal dimer of the desired zwitterionic silylene L'Si: (8). It has been reasoned that compound 8(2) may results from [4+1] cycloaddition of two molecules of 8 to give the transient dimer 8(2)', which subsequently ...

2009-08-01

371

A study of polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs) and polychlorinated biphenyls (PCBs) in the livestock waste compost of Hong Kong, PR China

A cross sectional study on the mineral density of the 3rd lumbar vertebral trabecular bone was carried out in 123 children less than 15 years old, comprising 44 controls, and 79 patients affected with conditions which are at risk for developing metabolic derangement of skeletal bone (34 patients taking antiepileptic drugs (AED), 29 undergoing glucocorticoid (GC) therapy and 16 bedridden patients), by using quantitative computed tomography (QCT) with a CaCO{sub 3} phantom. Serum Ca and alkaline-phosphatase (Alp) levels were measured at the time of QCT examinations in all. The results obtained were as follows: The QCT values in the control children showed neither age dependency nor a sexual difference before puberty. The QCT values in each group showed significant difference with one another; the control group>the AED group>the GC group>the bedridden group (p<0.05{approx}0.005). The serum Ca levels in each pathology group were significantly lower than ...

1991-06-01

372

What is the best contrast injection protocol for 64-row multi-detector cardiac computed tomography?

Composting is one of the waste disposal methods adopted for disposal of livestock waste in Hong Kong. The composting livestock waste normally undergoes 6-8 weeks fermentation, followed by 16-20 weeks maturation. The matured compost is sold as soil conditioner in the local market. In 2006, feedstock material and a time-series of compost samples were collected throughout the fermentation and maturation process from the Sha Ling Composting Plant in the New Territories. The feedstock material and compost samples were analyzed for contents of three unintentional persistent organic pollutants (POPs), i.e. dioxins/furans, dioxin-like PCBs and total PCBs. These POPs are unintentionally produced by-products of chemical industrial processes and combustion processes. Selected heavy metals were also analyzed, which served as conservative tracers to determine potential mass loss during the composting process. Levels of contamination by these POPs were found to be low in the ...

2008-07-01

373

Uptake of radiolabeled ions in normal and ischemia-damaged brain

Objective: To determine the optimal contrast injection protocol for 64-MDCT coronary angiography. Materials and methods: One hundred and fifty consecutive patients scheduled to undergo retrospectively electrocardiographically gated 64-MDCT. Each 30 patients were assigned to use a different contrast protocol: group 1: uniphasic protocol (contrast injection without saline flush); group 2: biphasic protocol (contrast injection with saline flush); group 3A, 3B and 3C: triphasic protocol (contrast media + different saline diluted contrast media + saline flush). Image quality scores and artifacts were compared and evaluated on both transaxial and three-dimensional coronary artery images among each contrast protocol. Results: Among the triphasic protocol groups, group 3A (30%:70% contrast media-saline mixture was used in second phase) used the least contrast media and had the least frequency of streak artifacts, but there were no significant differences in coronary artery ...

2010-08-01

374

Transport in a toroidally confined pure electron plasma

The regional concentrations of nine radiochemicals were measured in rat brain after induction of cerebral ischemia to identify tracers concentrated by brain undergoing selective neuronal necrosis. Transient (30 minute) forebrain ischemia was produced in the rat; 24 hours after cerebral recirculation the radiochemicals were injected intravenously and allowed to circulate for 5 hours. The brain concentrations of the radiochemicals in dissected regions were determined by scintillation counting. Forebrain ischemia of this nature will produce extensive injury to striatal neurons but will spare the great majority of neocortical neurons at 24 hours. The regional concentrations of these radiochemicals varied considerably in both control and ischemic animals. In postischemic animals, 4 radionuclides (/sup 63/Ni, /sup 99/TcO/sub 4/, /sup 22/Na, and (/sup 3/H)tetracycline) were concentrated in the irreversibly damaged striatum in amounts ranging from 1.4 to 2.4 times greater ...

1986-05-01

375

Transcutaneous oximetry compared to ankle-brachial-index measurement in the evaluation of percutaneous transluminal angioplasty

O close-quote Neil and Smith [T.M. O close-quote Neil and R.A. Smith, Phys. Plasmas 1, 8 (1994)] have argued that a pure electron plasma can be confined stably in a toroidal magnetic field configuration. This paper shows that the toroidal curvature of the magnetic field of necessity causes slow cross-field transport. The transport mechanism is similar to magnetic pumping and may be understood by considering a single flux tube of plasma. As the flux tube of plasma undergoes poloidal ExB drift rotation about the center of the plasma, the length of the flux tube and the magnetic field strength within the flux tube oscillate, and this produces corresponding oscillations in T_p_a_r_a_l_l_e_l and T_p_e_r_p_e_n_d_i_c_u_l_a_r. The collisional relaxation of T_p_a_r_a_l_l_e_l toward T_p_e_r_p_e_n_d_i_c_u_l_a_r produces a slow dissipation of electrostatic energy into heat and a consequent expansion (cross-field transport) of the plasma. In the limit where the cross section of ...

376

The Prognostic Significance of p53, Bcl-2, Cytokeratin 20 and Ki-67 in Primary Superficial Papillary Transitional Bladder Carcinoma

Objective: To investigate transcutaneous oximetry as parameter of the microcirculation is correlated to ankle-brachial-index as parameter of the macrocirculation after peripheral angioplasty procedures. Design: Prospective study. Materials and methods: 60 patients suffering from intermittent claudication were scheduled for angioplasty treatment. 45 patients were considered as eligible for angioplasty after angiographic evaluation, 15 patients underwent angiography only. Transcutaneous oximetry measurements were performed before the procedure, at the end of intervention, 24 h as well as 2 and 4 weeks after percutaneous transluminal angioplasty. Ankle-brachial-indices were obtained before intervention, 24 h as well as 2 and 4 weeks later. Results: Ankle-brachial-indices increased significantly at 24 h after angioplasty in patients being treated with angioplasty. Transcutaneous oximetry values dropped significantly at the end of the procedure and returned close to the baseline levels at 2 ...

2007-11-01

377

Scaling of the distribution function and the critical exponents near the point of a marginal stability under the Vlasov-Poisson equations

Identification of factors that determine individual patient risk for recurrence and progression in superficial papillary carcinoma of the bladder is a subject of extensive research as it would be a major outcome in patient management. It has been well recognized that traditional prognostic markers as tumor grade and stage are not accurate enough in predicting biological behavior. A large number of markers have been investigated as potential prognostic factors and relatively few can help in predicting outcome. Material and Methods: Forty-nine cases undergoing complete transurethral resection for primary superficial papillary transitional cell carcinoma were subjected to clinicopathologic evaluation as well as immunohistochemical staining for p53, bcl-2, cytokeratin 20 and Ki-67. The CAS-200 image analyzer was used to estimate the Ki-67 labeling index. Results: Recurrence was observed in 19 cases (38.8%) and progression in 7 cases (14.3%) with a median followup of 49 ...

2003-03-01

378

Radiological diagnosis of lesions of intervertebral discs; Radiologische Diagnostik von Bandscheibenlaesionen

A model system, described by the consistent Vlasov-Poisson equations under periodical boundary conditions, has been studied numerically near the point of a marginal stability. The power laws, typical for a system, undergoing a second-order phase transition, hold in a vicinity of the critical point: (i) A {proportional_to} -{theta}{sup {beta}}, {beta}=1.907{+-}0.006 for {theta} {<=} 0, where A is the saturated amplitude of the marginally-stable mode; (ii) {chi} {proportional_to} {theta}{sup -{gamma}} as {theta} {yields} 0, {gamma}={gamma}{sub -}=1.020{+-}0.008 for {theta} < 0, and {gamma}={gamma}{sub +}=0.995{+-}0.020 for {theta} > 0, where {chi}={partial_derivative}A/{partial_derivative}F{sub 1} at F{sub 1} {yields} 0 is the susceptibility to external drive of the strain F{sub 1}; (iii) at {theta}=0 the system responds to external drive as A {proportional_to} F{sub 1}{sup 1/{delta}}, and {delta}=1.544{+-}0.002. {theta}=(<v{sup ...

2000-08-01

379

Primary malignant lymphoma of the brain; Primaere maligne Lymphome des Gehirns

During their life, intervertebral discs undergo degenerative changes which need not necessarily become lesions. Conventional X-rays do not provide information on the condition of the intervertebral discs, so MRT or CT are recommended as primary techniques as they are non-invasive. Invasive methods like myelography and especially discography should not be used unless a case is highly problematic. In infants with pains in the back, MRT should be carried out as early as possible as there is nearly always an organic cause. (orig.) [German] Die Bandscheibe ist im Laufe des Lebens degenerativen Veraenderungen unterworfen, die klinisch zu Beschwerden fuehren koennen, aber nicht fuehren muessen. Konventionlle Roentgenaufnahmen lassen zwar die Hoehenminderung des Bandscheibenfachs und begleitende knoecherne Veraenderungen erkennen, nicht aber den Zustand der Bandscheibe selbst. Die Beurteilung der Bandscheibe und des Knochens gelingt mit der CT, die parallel zum ...

2003-03-01

380

Ozone removal by green building materials

Primary malignant lymphoma of the brain is a disease of unknown etiology, which is increasing in incidence and has an unfavorable prognosis. Despite the lack of specific changes on CT or MRI in most cases, these procedures may typically facilitate the diagnosis: A focal-enhancing mass with subependymal spread on CT or MRI and hyperattenuation on nonenhanced CT are the most reliable features in the diagnosis of primary malignant lymphoma of the brain. Peritumoral edema and mass effect are usually not prominent features. On unenhanced CT scans they usually appear homogeneously isodense to mildly hyperdense relative to the gray matter. On MRI these tumors are slightly hypointense on T1-weighted images and slightly hpyerintense on PD- and T2-weighted images relative to the gray matter. On CT and MRI enhancement is usually homogeneous. Contrast-enhanced MRI, with its multiplanar capability, lack of bone-induced artifacts, and high-contrast resolution, is likely to reveal subependymal spread ...

1997-01-01

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381

Modified nickel based standard brazing filler metals for units under corrosive loads; Modifizierte Nickelbasisstandardlote fuer korrosiv belastete Bauteile

Interest in finding out passive ways to keep the variation in the indoor climate within the comfort zone is gaining in popularity. One possible solution is the use of the moisture-buffering property of materials. In this study, the effects of the ventilation system and moisture-buffering properties of the building fabric on the stability of the indoor temperature and humidity are analysed by means of long-term field measurements. Indoor climate measurements were carried out in 170 detached houses (248 rooms). Temperature and relative humidity were measured continuously in bedrooms and living rooms at one-hour intervals over a one-year period. In general, it may be concluded that in this study, the ventilation had a greater effect on the indoor climate than the properties of the building fabric. The dampening effect of hygroscopic materials was remarkably less in the field measurements than it was in simulations in different studies. This indicates that completely non-hygroscopic and ...

2009-08-15

382

Mechanodynamical analysis of nickel-titanium alloys for orthodontics application; Analise mecanodinamica de ligas de niquel-titanio para aplicacao ortodontica

Nickel-based alloys are presently used as brazing filler metals for components which undergo mechanical stress in corrosive conditions, f. e. heat exchangers. When soldering chrome containing steel parts with nickel based brazing filler metals additionally containing boron and silicon a reaction of chrome and boron can occur. This evolution of chromium borides, depositing on grain boundaries, causes a lack of chrome in the steel part. A drop of the chrome content in the parts below 13 % leads to a loss of corrosion resistance. It is possible to change the microstructure of brazing joints by modification with chromium and molybdenum. Continuous brittle phases could be successfully avoided with this modification. Furthermore it could be shown that the choice of additives, the heating respectively cooling rate and the brazing temperature have important influence on the microstructure evolution and therefore on the mechanical and corrosive properties of joints. ...

2008-01-15

383

MRI in postoperative assessment of univentricular heart disease: correlation with echocardiography and angiography; MRT in der postoperativen Diagnostik bei funktionell univentrikulaerem Herz: Korrelation zu Echokardiographie und Kardangiographie

Nickel-titanium alloys may coexist in more than one crystalline structure. There is a high temperature phase, austenite, and a low temperature phase, martensite. The metallurgical basis for the superelasticity and the shape memory effect relies in the ability of these alloys to transform easily from one phase to another. There are three essential factors for the orthodontist to understand nickel-titanium alloys behaviour: stress; deflection; and temperature. These three factors are related to each other by the stress-deflection, stress-temperature and deflection-temperature diagrams. This work was undertaken with the objective to analyse commercial nickel-titanium alloys for orthodontics application, using the dynamical mechanical analyser - DMA. Four NiTi 0,017 X 0,025'' archwires were studied. The archwires were Copper NiTi 35 deg C (Ormco), Neo Sentalloy F200 (GAC), Nitinol Superelastic (Unitek) and NiTi (GAC). The different mechanodynamical properties such as ...

2002-07-01

384

Genes involved in immortalization of human mammary cells

Purpose: To determine the value of MRI in the postoperativ evaluation of a singular ventricle compared to echocardiography and cardiac catheterization. Materials and methods: Thirty-one patients (range: 6 months to 30 years) with a functional single ventricle following palliative corrective operations. Five patients had a Blalock-Taussig-Shunt, 8 patients a Glenn-Anastomosis and 18 a cavopulmonary shunt (6 with classic Fontan-Circulation, 12 with modified cavopulmonary anastomosis). The results in terms of postoperative morphologic changes were compared to percutaneous echocardiography (31/31) and cardiac catheterization (6/31). Results: Echocardiography, which was performed on all patients, could not visualize the entire length of the tunnel, the Glenn-Anastomosis or the central pulmonary arteries in 70% of the patients due to an inadequate acoustic window. MRI was able to show the entire tunnel in 11/12 patients and the central pulmonary arteries in 30/31 patients. The exact anatomy ...

2002-12-01

385

Energy optimal synthesis of perodic motions in multibody systems; Energieoptimale Synthese periodischer Arbeitsbewegungen in Mehrkoerpersystemen

Breast cancer progression is characterized by inappropriate cell growth. Normal cells cease growth after a limited number of cell divisions--a process called cellular senescence-while tumor cells may acquire the ability to proliferate indefinitely (immortality). Inappropriate expression of specific oncogenes in a key cellular signaling pathway (Ras, Raf) can promote tumorigenicity in immortal cells, while causing finite lifespan cells to undergo a rapid senescence-like arrest. We have studied when in the course of transformation of cultured human mammary epithelial cells (HMEC), the response to overexpressed oncogenic Raf changes from being tumor-suppressive to tumor enhancing, and what are the molecular underpinnings of this response. Our data indicate: (1) HMEC acquire the ability to maintain growth in the presence of oncogenic Raf not simply as a consequence of overcoming senescence, but as a result of a newly discovered step in the process of immortal ...

2001-09-27

386

Carbon-carbon bond formation in cationic aryl-olefin-platinum (II) complexes

In robotics inverse dynamics is a standard control concept for highly nonlinear multibody systems. It is shown, however, that inverse dynamics results in a high energy demand. Therefore, linear energy efficient state feedback controllers are designed in a way that a performance index representing the energy consumption is minimized. At the same time inequality constraints such as control error and limited input variables have to be met. For the control design an analytical solution by pole placement is presented as well as a numerical controller optimization. This control design includes small motions in the neighborhood of the operating point. Then, linear controllers are tested with respect to control error and energy consumption when undergoing large displacement motion. It is shown that linear state feedback can only save energy if large control errors are accepted. Therefore, nonlinear systems are optimized as a whole by implementation of springs as local ...

2006-07-01

387

CT-Expo - a novel program for dose evaluation in CT; CT-Expo - ein neuartiges Programm zur Dosisevaluierung in der CT

Cationic five-coordinate [Pt(3-R{sup 1}-4-R{sup 2}-C{sub 6}H{sub 3})(MeCN) (6-Me-py-2-CH=NPh)(C{sub 2}H{sub 4})]{sup +} complexes (R{sup 1}, R{sup 2} = H, Me, OMe) undergo an unexpected rearrangement at 0{degrees}C in chloroform solution, affording, after treatment with aqueous LiCl, the neutral four-coordinate species [Pt(2-Et-4-R{sup 1}-5-R{sup 2}-C{sub 6}H{sub 2})Cl(6-Me-py-1-CH=NPh)]. Pt-C{sub aryl} bond breaking and making is involved in the whole process, resulting in a 1,2-shift of the platinum atom to an adjacent position of the benzene ring. The same compound is obtained, together with products deriving from a typical insertion, when an equimolar amount of ethylene is added to a chloroform solution of [Pt(3-R{sub 1}-4-R{sup 2}-C{sub 6}H{sub 3})(MeCN)(6-Me-py-2-CH=NPh)]{sup +} at 0{degrees}C. When higher ethylene/Pt ratios are used, only five-coordinate [Pt(3-R{sup 1}-4-R{sup 2}-C{sub 6}H{sub 3}CH{sub 2}CH{sub 2})Cl(6-Me-py-2-CH{double_bond}NPh)(C{sub ...

1992-11-01

388

BULGE n AND B/T IN HIGH-MASS GALAXIES: CONSTRAINTS ON THE ORIGIN OF BULGES IN HIERARCHICAL MODELS

CT-Expo is a novel MS Excel application for assessing the radiation doses delivered to patients undergoing CT examinations, based on computational methods that were used to analyze the data collected in the German survey on CT practice in 1999. The program enables the calculation of all dose quantities of practical value, such as axial dose free-in-air, weighted CTDI, dose-length product, effective dose and uterine dose. In contrast to existing programs for CT dose assessment, CT-Expo offers a number of unique features, such as gender-specific dose calculation for all age groups (adults, children, newborns), applicability to all existing scanner models including correction of scanner-specific influences, and the possibility of comparison with the results from the German CT survey on CT practice. Three different application modules offer free and standardized dose calculations as well as a comprehensive benchmarking section including guidance on dose optimization. ...

2002-12-01

389

A dinuclear Ni(I) system having a diradical Ni2N2 diamond core resting state: synthetic, structural, spectroscopic elucidation, and reductive bond splitting reactions.

We use the bulge Sersic index n and bulge-to-total mass ratio (B/T) to explore the fundamental question of how bulges form. We perform two-dimensional bulge-disk-bar decomposition on H-band images of 143 bright, high-mass (M _* #>=# 1.0 x 10"1"0 M _s_u_n) low-to-moderately inclined (i < 70"0) spirals. Our results are as follows. (1) Our H-band bar fraction (#approx#58%) is consistent with that from ellipse fits. (2) 70% of the stellar mass is in disks, 10% in bars, and 20% in bulges. (3) A large fraction (#approx#69%) of bright spirals have B/T#<=# 0.2, and #approx#76% have low n #<=# 2 bulges. These bulges exist in barred and unbarred galaxies across a wide range of Hubble types. (4) About 65% (68%) of bright spirals with n #<=# 2 (B/T #<=# 0.2) bulges host bars, suggesting a possible link between bars and bulges. (5) We compare the results with predictions from a set of #LAMBDA#CDM models. In the models, a high-mass spiral can have a bulge with a present-day low ...

2009-05-01

390

Virtual colonoscopy (CT colonography) in the identification of colorectal cancer. A prospective study in symptomatic patients; Impiego dell'endoscopia virtuale con Tomografia Computerizzata nell'identificazione delle neoplasie colorettali. Studio prospettivo in pazienti sintomatici

One-electron reduction of the square-planar nickel precursor (PNP)NiCl ( 1) (PNP (-) = N[2-P(CHMe 2) 2-4-methylphenyl] 2) with KC 8 effects ligand reorganization of the pincer ligand to assemble a Ni(I) dimer, [Ni(mu 2-PNP)] 2 ( 2), containing a Ni 2N 2 core structure, as inferred by its solid-state X-ray structure. Solution magnetization measurements are consistent with a paramagnetic Ni(I) system likely undergoing a monomer dimer equilibrium. The room-temperature and 4 K solid-state X-band electron paramagnetic resonance (EPR) spectra display anisotropic signals. Low-temperature solid-state X-band EPR data at 4 K reveal rhombic values g z = 1.980(4), g x = 2. 380(4), and g y = 2.225(4), as well as a forbidden signal at g = 4.24 for the Delta M S = 2 half field transition, in accord with 2 having two weakly interacting metal centers. Utilizing an S = 1 model, full spin Hamiltonian simulation of the low-temperature EPR spectrum on the solid sample was achieved by ...

2008-10-15

391

In-vitro radioimmunoassay of prostate specific antigen (PSA) for the screening and management of prostate cancer in Lebanon

Aim of this study was to evaluate the sensitivity of virtual colonoscopy (CT colonography) in the identification of colorectal cancer and to define the limitations and the advantages of this imaging modality, as well as indications to the examination. It was examined prospectively 62 symptomatic patients aged 36 to 82 years (28 women and 34 men). All patients underwent both conventional and virtual colonoscopy on the same day; the conventional examination allowed exploration of the entire colon. Conventional colonoscopy identified 89 lesions 3-50 mm in diameter, namely 84 benign and 5 malignant lesions. No lesions were identified in 12 patients. CT colonography identified 52 of the 89 lesions, with 57.1% diagnostic accuracy. They were 11 false positives (82.5% positive predictive value and 52.2% specificity) and 37 false negatives (24.5% negative predictive value and 58.4% sensitivity). Sensitivity was significantly higher (85.7%) for polyps {>=} 1 cm. Virtual colonoscopy is an ...

2000-06-01

392

Behaviour of heat resistant power plant steels undergoing variable long term loading conditions

Full text: Immunoassays for prostate-specific antigen (PSA) are used to detect early-stage prostate cancer, monitor disease progress, and evaluate therapeutic response. At least two forms of PSA, free PSA (F-PSA) and PSA complexed to alpha-1 anti-chymotrypsin (PSA-ACT) are detected by commercial PSA assays. The fraction of F-PSA is shown to be smaller in patients with untreated prostate cancer than in patients with benign prostate hyperplasia (BPH). Thus, combined measurements of both total and free PSA are used for a better discrimination between BPH and prostate cancer. Detection of PSA for screening of prostate cancer has been a subject of debate for many years. The reason of this debate is mainly because screening for prostate cancer is not cost-effective, as was shown by studies undertaken in Europe and United States. In Lebanon, no previous programs of screening for prostate cancer were done and so the incidence of this cancer is not known. Recently, the cancer registry in ...

2004-01-01

393

A study of flow boiling phenomena using real time neutron radiography

High temperature components of power plants are in many cases subjected to variable loading conditions such as cyclic creep or strain cycling. Therefore the cyclic behaviour of important heat resistant steels has been investigated under stress control and to a smaller extent under strain control. The behaviour under cyclic creep rupture conditions was determined in long term experiments covering a wide range of loading conditions. This behaviour can be described with the modified life fraction rule and a factor concept of relative life for single stage cycles and additionally with a multistep hypothesis for multi-stage cycles. The description can be adapted to estimate the life consumption under service type random conditions. The strain cycling behaviour was investigated in regard to the conditions of the heated surface of large components. To simulate this type of loading and to generate long term creep fatigue data, a service type strain cycle was developed. Anisothermal and ...

2000-01-01

394

A multidisciplinary study investigating radiotherapy in Ewing's sarcoma: end results of POG no. 8346

The operation and safety of both fossil-fuel and nuclear power stations depend on adequate cooling of the thermal source involved. This is usually accomplished using liquid coolants that are forced through the high temperature regions by a pumping system; this fluid then transports the thermal energy to another section of the power station. However, fluids that undergo boiling during this process create vapor that can be detrimental, and influence safe operation of other system components. The behavior of this vapor, or void, as it is generated and transported through the system is critical in predicting the operational and safety performance. This study uses two advanced penetrating radiation techniques, Real Time Neutron Radiography (RTNR), and High Speed X-Ray Tomography (HS-XCT), to examine void generation and transport behavior in a flow boiling system. The geometries studied were tube side flow boiling in a cylindrical configuration, and a similar flow ...

1346-01-01

395

A multi-disciplinary study investigating radiotherapy in Ewing's sarcoma - a final report of POG 8346

Purpose: To determine if involved field radiation (IF) is equivalent to standard whole bone radiation (SF) in local tumor control; to establish patterns of failure following treatment; and to determine response, event-free survival (EFS), and overall survival rates from multidisciplinary therapy in Ewing's sarcoma. Methods and Materials: Between 1983 and 1988, 184 children with Ewing's sarcoma were enrolled onto Pediatric Oncology Group 8346 (POG 8346). A total of 178 (97%) met eligibility criteria; 6 had pathology other than Ewing's sarcoma. Induction chemotherapy of cyclophosphamide/doxorubicin (adriamycin )(C/A) x 12 weeks was followed by local treatment either surgery or radiation therapy and C/A, dactinomycin, and vincristine for 50 weeks. Resection was advised for patients with small primary tumors if accomplished without functional loss. Forty patients were randomized to receive SF, whole bone radiation to 39.6 Gy plus a 16.2 Gy boost (total 55.8 Gy) or IF to 55.8 Gy, and the ...

1998-08-01

396

STRUCTURE AND FORMATION OF ELLIPTICAL AND SPHEROIDAL GALAXIES

Purpose: To determine if involved field radiation (IF) is equivalent to standard whole bone radiation (SF) in local tumor control; to establish patterns of failure following treatment; and to determine response, event free (EFS) and overall survival rates from multi-disciplinary therapy in Ewing's Sarcoma (ES). Materials and Methods: Between 1983 and 1988, 184 children with ES were enrolled onto POG 8346. 178 (97%) met eligibility criteria; 6 had non-ES pathology. Induction treatment of Cyclophosphamide/Adriamycin (C/A) x 12 weeks was followed by local treatment either surgery or radiation therapy (XRT) and C/A, Dactinomycin and Vincristine for 50 weeks. Resection was advised for patients with small primary tumors if accomplished without functional loss. 40 patients were randomized to receive SF, whole bone XRT to 39.6 Gy plus a 16.2 Gy boost (total 55.8 Gy) or IF to 55.8 Gy while 84 were assigned to IF XRT. Results: Of 179 eligible patients, 141 (79%) had localized disease and 37 ...

397

Helical CT of traumatic injuries of the thoracic aorta; Applicazioni della Tomografia Computerizzata spirale nello studio delle lesioni traumatiche dell'aorta toracica

New surface photometry of all known elliptical galaxies in the Virgo cluster is combined with published data to derive composite profiles of brightness, ellipticity, position angle, isophote shape, and color over large radius ranges. These provide enough leverage to show that Sersic log I #propor to# r "1"/"n functions fit the brightness profiles I(r) of nearly all ellipticals remarkably well over large dynamic ranges. Therefore, we can confidently identify departures from these profiles that are diagnostic of galaxy formation. Two kinds of departures are seen at small radii. All 10 of our ellipticals with total absolute magnitudes M_V_T #<=# -21.66 have cuspy cores-"missing light"-at small radii. Cores are well known and naturally scoured by binary black holes (BHs) formed in dissipationless ("dry") mergers. All 17 ellipticals with -21.54 #<=# M_V_T #<=# -15.53 do not have cores. We find a new distinct component in these galaxies: all coreless ellipticals in our sample have ...

2009-05-01

398