UK PubMed Central (United Kingdom)

ObjectivesPericardial tamponade after cardiac surgery is difficult to diagnose, thereby rendering timing of rethoracotomy hard. We aimed at identifying factors predicting the outcome...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Audible noise from corona discharge had been identified as one of the most important factors in the design of conductor configurations for high-voltage transmission lines. 500 kV and above. Therefore this paper describes audible noise characteristics of 6 X 480 mm{sup 2} conductor bundle in KEPRI 765 kV Test Line and Corona Cage. Prediction formula for audible(corona) noise on a 765 kV Transmission Line was developed using this results. (author). 4 refs., 4 figs., 4 tabs.

Science.gov (United States)

OBJECTIVE To identify patients with gestational diabetes mellitus (GDM) who will need antenatal insulin treatment (AIT) by using a risk-prediction tool based on maternal clinical and biochemical characteristics at diagnosis. RESEARCH DESIGN AND METHODS Data from 3,009 women attending the Royal Prince Alfred Hospital GDM Clinic, Australia, between 1995 and 2010 were studied. A risk engine was developed from significant factors identified for AIT using a logistic regression model. RESULTS A total of 51% of GDM patients required AIT. Ethnicity, gestation at diagnosis, HbA(1c), fasting and 60-min glucose oral glucose tolerance test, BMI, and diabetes family history were significant independent determinants of AIT. Notably, only 9% of the attributable risk for AIT can be explained by the clinical factors studied. A modeled risk-scoring system was therefore a poor predictor of AIT. ...

British Library Electronic Table of Contents (United Kingdom)

Aim To better define the indications for adrenalectomy for adrenal metastasis we have analysed factors predicting survival in our institutional series. Methods A consecutive series of 30 patients undergoing adrenalectomy for metastasis (1996-2007), excluding patients with simultaneous ipsilateral renal cell carcinoma (RCC), was studied. Metastases were regarded as synchronous (6 mo), depending on the interval after primary surgery. Survival was calculated from time of adrenalectomy and factors influencing survival were identified. Results The tumour diagnoses were RCC n = 9, malignant melanoma n = 5, non-small-cell lung cancer n = 5, colorectal carcinoma n = 4, foregut carcinoid n = 2, adrenocortical carcinoma, breast cancer, hepatocellular carcinoma, urothelial c...

KoreaScience (Korea)

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Science.gov (United States)

To illustrate the implementation of a bottom-up approach to the study of culture in health disparities, this article describes the development of a cultural cancer screening scale (CCSS) using mixed methodologies. The aim was to identify cultural factors relevant to breast and cervical cancer screening, develop an instrument to assess them and examine its preliminary psychometric properties among Latin American (Latino) and non-Latino White (Anglo) women in Southern California. Seventy-eight Latino and Anglo women participated in semi-structured interviews, which were content coded based on Triandis' methods for the analysis of subjective culture. Based on the emerging cultural elements, items relevant to cancer screening were developed and pilot tested with 161 participants. After the instrument was refined, 314 Latino and Anglo women from various socioeconomic backgrounds completed the CCSS and data were factor analyzed ...

Energy Technology Data Exchange (ETDEWEB)

An overview of climatic factors and impact relative to river ice engineering and science is presented. An explanation of the fundamentals of climatic change is followed by a review of direct and indirect climatic influences that govern river ice breakup and related trends. Known responses of river ice to climatic change and potential future changes to ice breakup processes are described along with the probable ecological and socio-economic consequences of these changes. Changes in engineering approaches to accommodate the present ice regime and predicted changes in climatic variables that affect river ice processes and reduce the vulnerability of infrastructure and ecosystems to climatic change are examined. Future research on the links between river ice and stream ecology is suggested to identify ecological concerns that may result from changes in river ice regimes induced by climatic change. 60 refs., 3 figs.

UK PubMed Central (United Kingdom)

A fluid-phase immunoradiometric assay has been developed which identifies an antigen on the Factor VIII (antihemophilic factor) procoagulant protein. This sensitive and quantitative assay is not influenced...Full Text Available

UK PubMed Central (United Kingdom)

There are many methods to screen for abnormal amounts of proteinuria to identify patients at risk for progression of renal disease, but which method best predicts renal risk is unknown. Here, we analyzed...Full Text Available

International Nuclear Information System (INIS)

Purpose: To evaluate the outcomes of patients with Ewing's sarcoma family of tumors (ESFT) treated with modern radiotherapy techniques with MRI along with optimal chemotherapy. Methods and Materials: The records of all 60 patients with ESFT who received radiation to the primary site between 1990 and 2004 were reviewed. All patients received chemotherapy, including vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide. Radiation was used as the sole modality for local control in 31 patients and was given either before (n = 3) or after surgical resection (n = 26) in the remainder. All patients had MRI and CT scan-based treatment planning, and 43% received intensity-modulated radiation therapy. Radiation doses ranged from 30 Gy to 60 Gy (median, 51 Gy), and 35% received hyperfractionated radiotherapy. Results: Median age was 16 years (range, 2-40 years). Because of selection bias for radiotherapy, the majority of primary tumors were centrally located (72%): spine (n = 18), ...

UK PubMed Central (United Kingdom)

BackgroundAs long-term nursing home care is likely to increase with the aging of the population, identifying chronic medical conditions is of particular interest. Although need factors...Full Text Available

UK PubMed Central (United Kingdom)

Human epidermal growth factor receptor 2 (HER2) is one of the most important prognostic and predictive factors for breast cancer patients. Recently, serum HER2...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe aim of the present article was to evaluate whether angiogenic parameters as assessed by transvaginal color Doppler ultrasound (TVCD) may predict those prognostic factors...Full Text Available

UK PubMed Central (United Kingdom)

The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available

International Nuclear Information System (INIS)

The primary aim was to evaluate delayed contrast-enhanced MRI in depicting perineural spread of hilar cholangiocarcinoma (CCC) and consequently to determine the capability of MRI/MRCP for staging CCC. Fifteen patients that underwent MRI/MRCP and surgical treatment were retrospectively included. Two radiologists evaluated MR images to assess delayed periductal enhancement, extent of bile duct stenosis, liver parenchymal and vascular involvement and presence of liver atrophy. An agreement between delayed enhancement of the bile duct walls and perineural neoplastic spread showed a very good correlation factor (0.93). The overall accuracy in detecting biliary neoplastic invasion was higher for delayed T1-weighted images (93.3%) than for the MRCP images (80%), and T1-delayed image increased the MR accuracy in assessing the neoplastic resectability (p < 0.05). MRI correctly predicted vascular involvement in 73% and liver involvement in 80% of the ...

CERN Document Server

We combine a limited number of accurately measured transition frequencies in hydrogen and deuterium, recent quantum electrodynamics (QED) calculations, and, as an essential additional ingredient, a generalized least-squares analysis, to obtain precise and optimal predictions for hydrogen and deuterium transition frequencies. Some of the predicted transition frequencies have relative uncertainties more than an order of magnitude smaller than that of the g-factor of the electron, which was previously the most accurate prediction of QED.

British Library Electronic Table of Contents (United Kingdom)

Despite the proven utility of the Universal Soil Loss Equation (USLE) to predict soil rainfall erosion, it has limited precision in predicting soil loss in some soil series. Also, runoff is a factor in rainfall erosion and some models, such as the modified USLE (USLE-M), include runoff in predicting soil erosion. The soil erodibility factor is an essential component in both models and this may be affected by application of soil conditioners, such as polyacrylamide (PAM). The objectives of this study were to determine the effects of different rates of PAM (0, 1, 2, 4, and 6kgha-1) applied with sprinkler irrigation water, followed by two sprinkler irrigations with no PAM, on the erodibility of a loam soil under a rainfall simulator in a laboratory. The range of erodibility factor Ku obtained...

UK PubMed Central (United Kingdom)

Rodent models have been extensively utilized to identify putative human immunotoxicants; however, even when immunotoxicity is established, uncertainty remains whether the effects are predictive of human...Full Text Available

UK PubMed Central (United Kingdom)

Dopaminergic neurons of the ventral midbrain fire high frequency bursts when animals are presented with unexpected rewards, or stimuli that predict reward. To identify the afferents that can...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

In order to accurately assess the effectiveness of activated charcoal for the removal of radon from flowing air, a literature survey was performed to identify the models and relevant data that were available. It was found that by modifying the mathematical model of equilibrium stage theory used by Strong and Levins, the output rate of an activated charcoal filter exposed to a step function input in the radon rate at time zero with a given carrier gas flow velocity could be predicted. This paper outlines the modifications made to Strong and Levins's model and presents predictions for the filter output from the modified model.

UK PubMed Central (United Kingdom)

BackgroundInvasive Staphylococcus aureus infection is increasingly recognised as an important cause of serious sepsis across the developing world, with mortality...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundParents of chronically ill children are at risk for a lower Health Related Quality of Life (HRQoL). Insight in the dynamics of factors influencing parental HRQoL is necessary...Full Text Available

UK PubMed Central (United Kingdom)

The protozoan parasite Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical infection that affects millions of people in the Americas. Current chemotherapy...Full Text Available

Science.gov (United States)

This book chapter discusses sugarcane culture and history, describes arthropod biologies and injury, and identifies sugarcane pest management factors to consider for people interested in commercial sugarcane production. Arthropod groups include 10 orders and 40 families. Sugarcane pest management ...

UK PubMed Central (United Kingdom)

This study identified clinical (e.g., etiology) and demographic factors related to prosthesis use in persons with upper- and lower-limb amputation (ULA and LLA, respectively) and the effect...Full Text Available

UK PubMed Central (United Kingdom)

The purpose of this prospective cohort study was to identify factors that place a dairy cow with uncomplicated milk fever (MF) at significant risk of becoming an alert downer cow (ADC) and to verify...Full Text Available

UK PubMed Central (United Kingdom)

1. One hundred and thirty-two antidromically identified paraventricular (PV) and supraoptic (SO) neurones were studied during milk ejection evoked by the suckling of the young, in thirty-four lactating...Full Text Available

UK PubMed Central (United Kingdom)

Clostridium perfringens type A food poisoning is the second most commonly identified bacterial food-borne illness. Sporulation contributes to this disease in two ways: (i) most food-poisoning...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveThe purpose of this study is to identify the factors affecting the failure of trials (<50% pain reduction in pain for trial period) to improve success rate of spinal...Full Text Available

UK PubMed Central (United Kingdom)

Fifty-two isolates of Fusarium species were obtained from soybean seeds from various parts of Korea and identified as Fusarium oxysporum, F. moniliforme,...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The LAHET code system calculations and experimental results for proton interactions with an energy <50 MeV are compared. For these energies, the theories behind the LAHET models are not applicable. Three quantities compared are (a) the magnitude of the neutron yield generated through proton interactions, (b) the energy and angular distributions of the resultant neutrons, and (c) the residual nuclei produced by proton interactions (spallation products). The comparisons are for protons incident on iron and copper, except in the case of the energy and angular distributions, which are calculated only for iron. The neutron yields predicted by LAHET agree with published measurements to within 50% for both materials. For iron, the predicted energy and angular distributions agree to within a factor of 3. Finally, the predicted spallation product yields of both materials agree with measurements to within a ...

British Library Electronic Table of Contents (United Kingdom)

The aims of this study were to identify risk factors and evaluate the association with clinical outcomes of postoperative cardiac surgery-associated acute kidney injury (CSA-AKI). Data from 2488 consecutive adult patients were analyzed. Patients were classified as having CSA-AKI based on the risk, injury, failure, loss of kidney function, and end-stage kidney disease (RIFLE) criteria using peak postoperative creatinine in the postoperative intensive care unit (ICU). Multiple stepwise logistic regression analysis was used to identify independent risk factors for CSA-AKI. CSA-AKI occurred in 584 patients (23.5%). CSA-AKI patients had significantly longer aortic cross-clamp and cardiopulmonary bypass times. Furthermore, CSA-AKI patients had higher hospital mortality (5.5% vs 1.5%, PCopyright2...

DEFF Research Database (Denmark)

PURPOSE OF REVIEW: To review the recent literature on the prognostic value of biomarkers of liver fibrosis and impaired liver function in patients with chronic hepatitis C with or without HIV coinfection. RECENT FINDINGS: A combination of standard blood tests seems to be useful in identifying patients at risk of liver-related complications. Findings from studies investigating the validity of the Model for End-Stage Liver Disease (MELD) score in HIV-infected liver transplant candidates are conflicting. Two large studies of HIV/hepatitis C virus (HCV) coinfected patients have shown that plasma levels of the fibrosis marker hyaluronic acid are a strong predictor of clinical complications. A smaller study found hyaluronic acid and two other fibrosis tests, aspartate aminotransferase-to-platelet ratio index (APRI) and Fib-4, to be independent predictors of mortality when included in models with the MELD or the Child-Pugh-Turcotte scores. SUMMARY: Although the data are ...

Energy Technology Data Exchange (ETDEWEB)

A review of analytical design methods used for predicting reactor core flow and temperature distributions is presented with emphasis on LMFBR's. The paper also briefly describes and contrasts the methods used for LWR's. These methods are global analysis, subchannel analysis, distributed parameter, and hybrid analysis. The evolution of the local and subchannel analysis methods is presented. Data used for code validation are also presented. Current research and development needs are identified and discussed. Areas identified for future research and development include methods and expermental data for analysis of distorted bundles and natural convection. Methods that have been developed for predicting the safety performance of LMFBR's and LWR's are not within the scope of this paper.

British Library Electronic Table of Contents (United Kingdom)

Abstract This study presents a review of distributed model predictive control (DMPC) strategies followed by recent studies conducted by the authors on the robustness of these strategies to model errors and a summary of future challenges in this area. The review identifies three key challenges for the successful application of DMPC: (i) the selection of optimal control structure for DMPC; (ii) the choice of a suitable coordination strategy among the controllers; and (iii) the robustness of DMPC strategies to model errors. Then, the study summarises recent developments related to the robustness of unconstrained and constrained DMPC algorithms. For the unconstrained case, a methodology that is based on the calculation of a performance index is proposed to balance the trade-off between perform...

Energy Technology Data Exchange (ETDEWEB)

Decay sequences based on the 1/2/sup +/(660) proton orbital have been identified in /sup 171/Ta and /sup 177/Re based on spin, parity, and large alignment. This decay sequence is observed higher in energy than predicted in cranking calculations based on modified oscillator potentials. Similarly known 1/2/sup -/(541) decay sequences in these and other neighbouring isotopes are observed lower in energy than predicted. A reduction in the strength of the spin-orbit potential for protons is suggested as a solution to these problem.

Science.gov (United States)

Available from UMI in association with The British Library. Requires signed TDF. Design of time and correlation windows for non -parametric frequency response estimates. The thesis deals with problems that arise in the field of spectral analysis due to finite observations of input and output records. In particular, it is concerned with the method of applying time and correlation windows in spectral analysis procedures to obtain non-parametric frequency response estimates of open-loop time invariant systems. The thesis reviews and develops the sources of error that arise when frequency response techniques are applied directly to windowed records of input and output data to estimate the frequency response of open loop systems. Having identified the cause of these errors, methods of eliminating or reducing them are studied. The techniques introduced involve the use of differing time windows for the input and output data records. It is shown that windows can be ...

CERN Document Server

Simple, one-zone models for inhomogeneous chemical evolution of the Galactic halo are used to predict the number fraction of zero-metallicity, Population III stars, which currently is empirically estimated at < 4e-4. These analytic models minimize the number of free parameters, highlighting the most fundamental constraints on halo evolution. There are disagreements of at least an order of magnitude between observations and predictions in limiting cases for both homogeneous Simple Model and Simple Inhomogeneous Model (SIM). Hence, this demonstrates a quantitative, unambiguous discrepancy in the observed and expected fraction of Population III stars. We explore how the metallicity distribution of the parent enrichment events f(z_0) drives the SIM and predictions for the Population III fraction. The SIM shows that the previously-identified "high halo" and "low halo" populations are consistent with a ...

Energy Technology Data Exchange (ETDEWEB)

Both the KRW fluidized-bed gasifier and the transport gasifier case studies were used for this assessment. The transport technology is a high-velocity circulating fluidized-bed reactor currently under development by The M.W. Kellogg Company. In the earlier assessment, seven design concepts or cases were identified; a process design was developed; major equipment items were identified; estimates of capital cost, operation and maintenance cost, and cost of electricity were developed; reliability was predicted; and development issues were identified for six studies. Three of the most probable cases were further evaluated for a Greenfield assessment in this report to adequately determine all costs independent of facilities at Plant Wansley.

International Nuclear Information System (INIS)

One normally identifies the prediction of tachyons with a higher spin problem. We show that the same phenomenon also happens with certain spin-1/2 equations, in exactly the same circumstances. Furthermore, we prove that these equations also have the defect of possessing solutions with complex energies, even with the smallest external fields. The consequences of these results are analyzed.

British Library Electronic Table of Contents (United Kingdom)

Predicted by stochastic models and observed experimentally in a number of isomerization reactions, viscosity-induced solvent effects manifest themselves in a significant departure of the reaction rates from the values expected on the basis of transition state theory. These effects are well understood within the framework of stochastic models; however, the predictive power of such models is limited by the fact that their parameters are not readily available. Experiment and molecular dynamics (MD) simulations can provide such information and can serve as the testing grounds for various stochastic models. In real solvents, a change in viscosity is inevitably associated with variation of at least one of the three factors - temperature, pressure, or solvent identity, resulting in different solv...

International Nuclear Information System (INIS)

Aim of this study was to evaluate the sensitivity of virtual colonoscopy (CT colonography) in the identification of colorectal cancer and to define the limitations and the advantages of this imaging modality, as well as indications to the examination. It was examined prospectively 62 symptomatic patients aged 36 to 82 years (28 women and 34 men). All patients underwent both conventional and virtual colonoscopy on the same day; the conventional examination allowed exploration of the entire colon. Conventional colonoscopy identified 89 lesions 3-50 mm in diameter, namely 84 benign and 5 malignant lesions. No lesions were identified in 12 patients. CT colonography identified 52 of the 89 lesions, with 57.1% diagnostic accuracy. They were 11 false positives (82.5% positive predictive value and 52.2% specificity) and 37 false negatives (24.5% negative predictive value and 58.4% ...

British Library Electronic Table of Contents (United Kingdom)

An energy transfer and conversion model for high-temperature solar cavity receivers has been developed using the transport behaviour of solar radiation as described by the spectral radiative exchange factors. A Monte-Carlo ray-tracing method coupled with optical properties was adopted, to predict radiation characteristics of the solar collector system by calculating radiative exchange factors. A cavity receiver with a plano-convexo quartz window was proposed, based upon the directional characteristics of the focal flux and the redistribution effect of the quartz window. Parametric studies on the windowed receiver provided a more uniform flux distribution, higher efficiency and lower loss than the windowless receivers. The predicted results serve as a design reference for the solar receiver...

International Nuclear Information System (INIS)

Dryout predictions using a multi-flood model for the annular two-phase flow regime are compared against dryout data obtained for BWR condition. The multifluid model treats two-phase flow as composed of distinct fluid regions (fluids) and individual conservation equations are applied to each fluid. Dryout is assumed to occur when flow rate of one of the liquid films becomes zero. The factor is extended to cover dryout data for very short boiling lengths. The present study involves wide ranges in geometries, heat flux distributions, and fluid concentrations. The accuracy of dryout power prediction is found to be as good as that of empirical correlations. It is confirmed that within a single analytical framework, the model can handle various classes of dryout analyses whereas the existing equilibrium models cannot.

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study was to assess the utility of the Arabic translation of the Alcohol Use Disorders Identification Test (AUDIT) among a sample of male Muslim prisoners (N = 107) in Dubai, United Arab Emirates (UAE). Confirmatory factor analysis indicated a two-factor model to be the best fit of the data. Good internal reliability (a =.91) and predictive validity were also observed. While the limitations of the study are observed, these promising results suggest that the Arabic version of the AUDIT is a reliable and sound measure of alcohol use disorders among prisoners in the UAE.

Science.gov (United States)

The Predictive Capability Maturity Model (PCMM) is a new model that can be used to assess the level of maturity of computational modeling and simulation (M&S) efforts. The development of the model is based on both the authors experience and their analysis of similar investigations in the past. The perspective taken in this report is one of judging the usefulness of a predictive capability that relies on the numerical solution to partial differential equations to better inform and improve decision making. The review of past investigations, such as the Software Engineering Institute's Capability Maturity Model Integration and the National Aeronautics and Space Administration and Department of Defense Technology Readiness Levels, indicates that a more restricted, more interpretable method is needed to assess the maturity of an M&S effort. The PCMM addresses six contributing elements to M&S: (1) representation and geometric ...

Science.gov (United States)

We present a Poincare covariant Faddeev equation, which enables the simultaneous prediction of meson and baryon observables using the leading order in a truncation of the Dyson-Schwinger equations that can systematically be improved. The solution describes a nucleon's dressed-quark core. The evolution of the nucleon mass with current-quark mass is discussed. A nucleon-photon current, which can produce nucleon form factors with realistic Q{sup 2} evolution, is described. Axial-vector diquark correlations lead to a neutron Dirac form factor that is negative, with r{sub 1}{sup nu}>r{sub 1}{sup nd}. The proton electric-magnetic form factor ratio falls with increasing Q{sup 2}.

International Nuclear Information System (INIS)

"1"2"9I global distribution due to biogeochemical cycle in environment reservoirs has been studied. It is shown that during the operation of nuclear fuel cycle facilities and at a modern level of the decontamination factor the "1"2"9I concentration in some natural media (soil, the Earth biosphere, ocean mixing layer) will increase by 4-5 orders. Recommended gradual increase of the decontamnation factor in time for conserving the "1"2"9I concentration level not exceeding one order in comparison with modern one is given. At that to the end fof the centary the decontamination factor must be of an order of 1x10"4 in the case of "1"2"9I intake to the ocean mixing layer and of 1x10"5 in the case of its intake to the atmosphere.

Energy Technology Data Exchange (ETDEWEB)

We discuss the description of the proton structure function within the dipole factorization framework. We parameterize the forward dipole amplitude to account for saturation as predicted by the small-x QCD evolution equations. Contrarily to previous models, the saturation scale does not decrease when taking heavy quarks into account. We show that the same dipole amplitude also allows to reproduce diffractive data and exclusive vector meson production.

UK PubMed Central (United Kingdom)

Purpose:To report the preoperative best-corrected visual acuity (BCVA) and foveal thickness (FT) values that lead to a postoperative decimal BCVA of ≥1.0 after surgical removal...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Explicit analytical formulas are derived for the stress intensity factors at the tips of a main crack and of a microcrack for the two-dimensional case of a collinear microcrack. This configuration is used to derive an estimate of the toughness degradation due to microcracks linking up with an advancing main crack. The implications of this estimate for theoretical predictions of the toughening due to stress-induced microcracking are discussed.

British Library Electronic Table of Contents (United Kingdom)

Meningococcal disease is an infection caused by Neisseria meningitidis. Genetic factors contribute to host susceptibility and progression to disease, but the genes responsible for disease development are largely unknown. We report here a genome-wide association study for host susceptibility to meningococcal disease using 475 individuals with meningococcal disease (cases) and 4,703 population controls from the UK. We performed, in Western European and South European cohorts (consisting of 968 cases and 1,376 controls), two replication studies for the most significant SNPs. A cluster of complement factor SNPs replicated independently in both cohorts, including SNPs within complement factor H (CFH) (rs1065489 (p.936D

British Library Electronic Table of Contents (United Kingdom)

Erythroid differentiation regulator (Erdr1) was first discovered in mouse leukemia cell lines and functions as a stress-related survival factor. This study investigated whether Erdr1 regulates murine melanoma progression, as well as the mechanism involved in Erdr1-regulated metastasis. The expression of Erdr1 is negatively correlated with IL-18 expression, which has a pro-cancer effect in melanoma. To study the role of Erdr1 as an anti-cancer factor, cell migration, invasion, and proliferation were measured. Erdr1 overexpression markedly inhibited the level of cell migration, invasion, and proliferation in B16F10 cells in vitro. In addition, Erdr1 overexpression significantly suppressed melanoma lung colonization, metastasis, and tumor growth in vivo. To identify the factors involved in Er...

UK PubMed Central (United Kingdom)

BackgroundCoiled-coil domain containing 115 (Ccdc115) or coiled coil protein-1 (ccp1) was previously identified as a downstream gene of Fibroblast Growth Factor 2 (FGF2) highly expressed...Full Text Available

Environmental Research Database

DescriptionIron deficiency anaemia is a common problem and may be particularly important to certain groups of vegetarians. This project investigates isolating and identifying iron-binding constituents of meat digests using human Caco-2 cell lines. Stable isotope techniques used to test whether one or more of these compounds enhance iron absorpion in vivo and could therefore be added to vegetarian products to imporve iron nutrition.

British Library Electronic Table of Contents (United Kingdom)

Abstract The success of software projects is quite subjective in nature and is fettered by many risks, the perception of which varies from individual to individual and largely depends on the demographic characteristics of the executives and even the characteristics of the project. This study aims to identify and gauge the software risk dimensions and analyze the differences of perception among executives toward software risks. The contributions of this study untangle the issues underlying risks in the software industry and associates these issues with the perception of the -human- factor present in the industry.

UK PubMed Central (United Kingdom)

To understand how DEXD/H-box proteins recognize and interact with their cellular substrates, we have been studying Prp28p, a DEXD/H-box splicing factor required for switching the U1 snRNP with the U6...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The performance of more than 3,000 offshore platforms in the Gulf of Mexico was observed during the passage of Hurricane Andrew in August 1992. This event provided an opportunity to test the procedures used for platform analysis and design. A global bias was inferred for overall platform capacity and loads in the Andrew Joint Industry Project (JIP) Phase 1. It was predicted that the pile foundations of several platforms should have failed, but did not. These results indicated that the biases specific to foundation failure modes may be higher than those of jacket failure modes. The biases in predictions of foundation failure modes were therefore investigated further in this study. The work included capacity analysis and calibration of predictions with the observed behavior for 3 jacket platforms and 3 caissons using Bayesian updating. Bias factors for two foundation failure modes, lateral shear and ...

Science.gov (United States)

A series of studies conducted to identify the factors that block and unblock problem solving is described. Through the construction of an isomorph of the classic "water jar" problems developed by A. S. Luchins (1942) as a dynamic graphic micro-world, several factors involved in producing blocked states were identified. Subjects included 10 individuals and 10 pairs of subjects. By comparing the behavior of individuals tackling the "missionaries and cannibals" problem to that of pairs of subjects solving this problem, a study identified means by which problem solvers operating in a social context are able to overcome blocks that discourage individuals. These studies point to the importance of "reflection" (evaluation of problem-solving results) for flexible problem solving. This research suggests that teaching students to analyze what they have done will help them develop flexibility ...

Science.gov (United States)

This paper deals with the experimental identification and the validation of a non-parametric probabilistic approach allowing model uncertainties and data uncertainties to be taken into account in the numerical model developed to predict low- and medium-frequency dynamics of structures. The analysis is performed for a composite sandwich panel representing a complex dynamical system which is sufficiently simple to be completely described and which exhibits, not only data uncertainties, but above all model uncertainties. The dynamical identification is experimentally performed for eight panels. The experimental frequency response functions are used to identify the non-parametric probabilistic approach of model uncertainties. The prediction of the low- and medium-frequency dynamical responses obtained with the stochastic system is compared with the experimental measurements.

Energy Technology Data Exchange (ETDEWEB)

A detailed chemical kinetic reaction mechanism is developed to describe incineration of the chemical warfare nerve agent sarin (GB), based on commonly used principles of bond additivity and hierarchical reaction mechanisms. The mechanism is based on previous kinetic models of organophosphorus compounds such as TMP, DMMP and DIMP that are often used as surrogates to predict incineration of GB. Kinetic models of the three surrogates and GB are then used to predict their consumption in a perfectly stirred reactor fueled by natural gas to simulate incineration of these chemicals. Computed results indicate that DIMP is the only one of these surrogates that adequately describes combustion of GB under comparable conditions. The kinetic pathways responsible for these differences in reactivity are identified and discussed. The most important reaction in GB and DIMP that makes them more reactive than TMP or DMMP is found to be a ...

Energy Technology Data Exchange (ETDEWEB)

The purpose of this project was to compile a bibliography of references containing environmental transuranic radionuclide data. The authors intent was to identify those parameters affecting transuranic radionuclide transport that may be generic and those that may be dependent on chemical form and/or environmental conditions. An understanding of the unique characteristics and similarities between source terms and environmental conditions relative to transuranic radionuclide transport and cycling will provide the ability to assess and predict the long term impact on man and the environment. An additional goal of the literature review, was to extract the ranges of environmental transuranic radionuclide data from the identified references for inclusion in a data base. Related to source term, these ranges of data can be used to calculate the dose to man from the radionuclides, and to perform uncertainty analyses on these dose ...

British Library Electronic Table of Contents (United Kingdom)

An observational cohort study was conducted to compare the performance of the RIFLE (risk, injury, failure, loss and end-stage kidney disease), AKIN (acute kidney injury network) and conventional graded criteria to identify acute kidney injury (AKI) following SCT and to predict long-term mortality in 141 myeloablative allogeneic SCT (m-allo), 60 non-myeloablative allogeneic SCT (nm-allo) and 48 autologous SCT (auto) cases. The AKIN criteria had less ability to identify patients as having the lowest category, stage 1 (analogous to RIFLE risk): 33% (37%) in m-allo, 23% (32%) in nm-allo and 8.3% (16.7%) in auto. Cox regression showed that categories higher than the intermediate stage were independent predictors of mortality in all three definitions. The areas under receiver operating characte...

International Nuclear Information System (INIS)

The purpose of organization and management development activities in the commercial nuclear power industry is to foster high levels of power plant performance and safety through improved human performance. The NRC has been working to develop assessment tools to assay the effects of organizational factors on plant safety. The utility industry has been working on initiatives targeting individual accountability, the improvement of plant performance and the elimination of the items identified through the NRC assessment process. Organization and management activities do not focus on industry organizational charts, but on the personnel processes and dimensions (factors) that affect safety and economic performance. As individual terms these activities are often combined and referred to as organizational factors. As an area of study, organizational factors has become more prominent as the ...

Energy Technology Data Exchange (ETDEWEB)

The Flory model is applied to predict the isobaric expansion coefficients, {alpha}{sub P}, isentropic, {kappa}{sub S}, and isothermal, {kappa}{sub T}, compressibilities and speeds of sound, u, of the highly complex mixtures: hydroxyether + alkane, + dibutylether, + 1-butanol or + 2-methoxyethanol, 1-alkanol + alkane, and 1-alkanol + dibutylether. Predictions were obtained using the energetic parameter, {chi}{sub 12}, determined from values of excess enthalpies, H{sup E}, and from values of the excess isochoric internal energies, U{sub V}{sup E}, at equimolar composition. No meaningful differences exist between such predictions. Deviations between experimental and calculated values are lower than 2% for mixtures containing alkoxyethanols. Poorer results are obtained for 1-alkanol + dibutylether mixtures with deviations up to 5%. It is shown that predictions on {alpha}{sub P}, {kappa}{sub S}, {kappa}{sub ...

Energy Technology Data Exchange (ETDEWEB)

Predictions for E2, M1, and M4 transition rates and moments, together with examples of transition-charge densities, are presented for states of N = 50 nuclei. These predictions are based on one-body spectroscopic amplitudes obtained from the wave functions of a new N = 50 shell-model calculation which incorporates the 0f/sub 5/2/, 1p/sub 3/2/, 1p/sub 1/2/, and 0g/sub 9/2/ single-particle orbits and an empirically determined effective Hamiltonian for this space. The predictions are compared with experimental data, first in order to evaluate how well the model space, as applied by this Hamiltonian, accounts for observations, and then to assess the importance of configurations excluded from the model space and to determine the values of the operator renormalizations (effective charges and effective g factors) which optimally map the theoretical results onto the corresponding experimental values.

Energy Technology Data Exchange (ETDEWEB)

The predicted results of INDAC code were compared with measured {sup 3}H concentrations in air and pine-needle around the Wolsung site. The optimal sets of input data to INDAC were in addition selected by comparing the measured values with the predicted values of INDAC based on various conditions such as the release modes of effluents into the environment, the classification of wind classes, and the consideration of terrain. The predicted {sup 3}H concentrations in air and pine-needle were shown to have good agreement with measured values, although there are some limitations such as uncertainties in measured values, complex topology around the site, and the land-sea breeze effects. The assumption on the {sup 3}H behavior in vegetables or plants that the ratio of {sup 3}H concentration in plant water to {sup 3}H concentration in atmospheric water is 1/2 was shown to be conservative in terms of the audit calculation performed ...

International Nuclear Information System (INIS)

We summarize the predictions of different models for total #gamma##gamma# cross-sections. The experimentally observed rise of #sigma#_#gamma#_#gamma# with s radical _#gamma#_#gamma#, faster than that for #sigma#_p_-_b_a_r_p, #sigma#_#gamma#_p is in agreement with the predictions of the Eikonalized Minijet Models as opposed to those of the Regge-Pomeron models. We then show that a measurement of #sigma#_#gamma#_#gamma# with an accuracy of < or approx. 8-9% (6-7%) is necessary to distinguish among different Regge-Pomeron type models (the different parameterisations of the EMM models) and a precision of < or approx. 20% is required to distinguish the predictions of the EMMs and of those models which treat 'photon like a proton', for the energy range 300< s radical_#gamma#_#gamma# <500 GeV. We further show that the difference in model predictions for #sigma#_#gamma#_#gamma# of about a ...

Energy Technology Data Exchange (ETDEWEB)

To predict air quality properly at a given location, it is necessary to identify all emission sources that will have significant impact at that location. Furthermore, the atmospheric pollutants that are emitted by these sources must be identified and quantitatively characterized. Once the air-quality predictions have been made, it is desirable to have some historical air-quality data for comparison. An efficient means of obtaining this information is through the use of detailed emission inventories and an inventory of air-quality-monitoring stations. Therefore, as part of the Alberta Government/Industry Acid Deposition Research Program (ADRP), three comprehensive inventories have been developed, namely: a sulfur dioxide (SO/sub 2/) emission inventory, a nitrogen oxides (NOx) emission inventory, and an inventory of air-quality-monitoring stations. Volume 2, Design of the Emission Inventory, presents ...

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This report documents an analytical prediction of some of the characteristics which presently undiscovered faster-than-light sub-atomic particles (called tachyons) must possess if they are to exist without violating the Theory of Special Relativity. A brief review of necessary concepts from the Special Theory is included so that the reader might more readily understand the reasoning as it is developed. Necessary, but not all, characteristics of tachyons are then identified and presented. Finally, an interesting potential relationship between tachyons and anti-gravity is discussed.

Energy Technology Data Exchange (ETDEWEB)

Compact heat exchangers are being increasingly considered for condensation applications in the process, cryogenic, aerospace, power and refrigeration industries. In this paper, different configurations available for condensation applications are analyzed and the current state-of-the-knowledge for the design of compact condensers is evaluated. The key technical issues for the design and development of compact heat exchangers for condensation applications are analyzed and major advantages are identified. The experimental data and performance prediction methods reported in the literature are analyzed to evaluate the present design capabilities for different compact heat-exchanger configurations. The design flexibility is evaluated for the development of new condensation applications, including integration with other process equipment.

International Nuclear Information System (INIS)

The main objective of this paper is to identify conditions which affect public concern (either increase or decrease) and political acceptance for developing and implementing programmes for geologic disposal of long-lived radioactive waste. It also looks how citizens and relevant actors can be associated in the decision making process in such a way that their input is enriching the outcome towards a more socially robust and sustainable solution. Finally, it aims at learning from the interaction how to optimise risk management addressing needs and expectations of the public and of other relevant stakeholders. In order to meet these objectives, factors of relevance for societal acceptance conditions are identified, described and analysed. Subsequently these factors are looked for in the real world of nuclear waste management through cases in several countries. The analysis is conducted for six stages of a ...

Energy Technology Data Exchange (ETDEWEB)

In order to predict thermal hazards of high-energy materials, accurate kinetics constants must be determined. Predictions of thermal hazards for mixtures of high-energy materials require measurements on the mixtures, because interactions among components are common. A differential-scanning calorimeter (DSC) can be used to observe rate processes directly, and isothermal methods enable detection of mechanism changes. Rate-controlling processes will change as components of a mixture are depleted, and the correct depletion function must be identified for each specific stage of a complex process. A method for kinetics measurements on mixed explosives can be demonstrated with Composition B is an approximately 60/40 mixture of RDX and TNT, and is an important military explosive. Kinetics results indicate that the mator process is the decomposition of RDX in solution in TNT with a perturbation caused by interaction between the two ...

Energy Technology Data Exchange (ETDEWEB)

To significantly improve the simulation of climate by general circulation models (GCMs), systematic errors in representations of relevant processes must first be identified, and then reduced. This endeavor demands that the GCM parameterizations of unresolved processes, in particular, should be tested over a wide range of time scales, not just in climate simulations. Thus, a numerical weather prediction (NWP) methodology for evaluating model parameterizations and gaining insights into their behavior may prove useful, provided that suitable adaptations are made for implementation in climate GCMs. This method entails the generation of short-range weather forecasts by a realistically initialized climate GCM, and the application of six-hourly NWP analyses and observations of parameterized variables to evaluate these forecasts. The behavior of the parameterizations in such a weather-forecasting framework can provide insights on how these schemes ...

International Nuclear Information System (INIS)

With the preeminence of A-15 superconducting multifilamentary wires in magnet technology, it has become important to understand the thermodynamic factors influencing the formation of these compounds under solid-state reaction conditions. The six systems Nb--Sn, Nb--Ga, Nb--Ge, Nb--Al, V--Si, and V--Ga were prepared as single filament bronze wires and heat treated in an attempt to precipitate the appropriate A-15 compound. The compounds observed to form were categorized using a formation temperature ratio (stability index) based on the melting temperatures of the constituents which make up the single filament composites. This study has led to several predictions regarding the formation of A-15 compounds using a solid-state bronze diffusion technique. The results of experimentation based on these predictions are presented.

International Nuclear Information System (INIS)

A photoacoustic (PA) imaging system based on an ultrasonic Fresnel zone plate (FZP) transducer is developed for the purpose of imaging biological tissue. This FZP transducer has a two-zone negative zone plate piezoelectric material pattern, and an optical fibre is integrated with the transducer on the symmetric axis of the zone plates to deliver laser pulses to the sample. The focal characteristic of the FZP transducer is analysed by theoretical prediction and experimental measurement, and the measured results are in good agreement with the predicted results. The limited-field back-projection deconvolution algorithm combined with the coherence-factor weighting technique is used to reconstruct the optical absorption distribution. The experiments were performed with phantoms and the blood vessels of chicken embryo chorioallantoic membrane. The results demonstrate that PA imaging using the FZP transducer has the ability to ...

International Nuclear Information System (INIS)

Ageing of nuclear power plants means evolution of material or equipment properties on one side, and evolution of personnel skill and procedure adequacy on the other side, both of which, after a certain time, may not be compatible with the required safety provisions, or with an economic operation of the plant. Repair or replacement of components, as well as change in service conditions for a better compatibility with component reduced capabilities can be used to mitigate ageing effects. The paper summarises the results of a study conducted in this field with the support of the European Commission. It presents: the synthesis of the work done under international auspices, and in the European context; the comparison of ageing management approaches used in several European countries with international recommendations; the summary of the various potential phenomena and their governing parameters, the methods of in-service ageing identification and possible mitigation methods; illustrative ...

International Nuclear Information System (INIS)

The purpose of this experimental study is to investigate the micromechanical fatigue behavior, in terms of slip nature and preferential cracking sites, of a commercial #alpha#/#beta#-forged Ti-6Al-4V alloy. Electron backscattering diffraction is extensively used to identify the deformation (prismatic, basal, pyramidal slip) and crack formation modes activated by fatigue at the surface of several hundred primary #alpha# nodules. Some fatal crack formation sites are also characterized. Cracking in basal planes is identified as the most critical damage mode leading to fracture. An explanation is proposed which involves the resolved shear stress, taking into account the Schmid factor and the normal stress in relation to the elastic anisotropy of the #alpha#-phase. Finally, the spatial distribution of the secondary cracks is analyzed according to the crystallographic textures (macrozones) present on a mesoscopic scale in the ...

British Library Electronic Table of Contents (United Kingdom)

The dramatic increase in diagnostic rates of bipolar disorder in children and adolescents in the USA has led to an intense interest in the phenomenology of the disorder. Here we present data from a newly-developed instrument to assess episodic mania-like symptoms in youth in a large population-based sample (N?=?5326) using parent- and self-report. We found that a substantial proportion of children screened positive for having episodes of ?going high? and were at an increased risk for morbidity and impairment. Using factor analysis, we identified that episodic mania-like symptoms comprised two dimensions: An under-controlled dimension that was associated with significant impairment, and a low-risk exuberant dimension. Using latent class analysis, we identified a small group of children scor...

International Nuclear Information System (INIS)

The unsteady flow and heat transfer are simulated using LES and DNS for a channel with two angled ribs as a vee-shaped vortex generator to augment heat transfer. The vortex generators are attached on the bottom wall of the channel and their angles in respect to the main flow are between 10"o and 30"o. The Prandtl number is 0.71 and the Reynolds numbers based on the inflow velocity and the height of channel are from 200 to 2000. Based on the results of this work, the variations of the Nusselt number, pressure coefficient, bulk temperature, friction factor and Colburn factor with the Reynolds numbers and the incidence angles are provided. The relation between the key parameters of the velocity (friction factor f) and thermal (Colburn factor J) boundary layers is calculated for all cases and their values are compared with the predicted values by the Chilton-Colburn analogy. A ...

Energy Technology Data Exchange (ETDEWEB)

The goal of this project is to provide materials engineers, chemical engineers and plant operators with a software tool that will enable them to predict localized corrosion of process equipment including fabricated components as well as base alloys. For design and revamp purposes, the software predicts the occurrence of localized corrosion as a function of environment chemistry and assists the user in selecting the optimum alloy for a given environment. For the operation of existing plants, the software enables the users to predict the remaining life of equipment and help in scheduling maintenance activities. This project combined fundamental understanding of mechanisms of corrosion with focused experimental results to predict the corrosion of advanced, base or fabricated, alloys in real-world environments encountered in the chemical industry. At the heart of this approach is the development of models ...

International Nuclear Information System (INIS)

This is the first volume of a two-volume report. Volume 2 will be published at a later date. This report presents the results of a research project conducted by Brookhaven National Laboratory for the United States Nuclear Regulatory Commission, Office of Nuclear Regulatory Research. The purpose of the project was to develop a general methodology to be use in the assessment of the organizational factors which affect performance reliability (safety) in a nuclear power plant. The research described in this report includes the development of the Nuclear Organization and Management Analysis Concept (GNOMIC). This concept characterizes the organizational factors that impact safety performance in a nuclear power plant and identifies some methods for systematically measuring and analyzing the influence of these factors on safety performance. This report is divided into two parts; Part 1 presents an overview of ...

British Library Electronic Table of Contents (United Kingdom)

Soil erodibility (the K factor in the Universal Soil Loss Equation, USLE) is an important index to measure soil susceptibility to water erosion, and an essential parameter needed for soil erosion prediction. To evaluate the appropriateness of the nomograph and other methods for estimating the K factor for the USLE and to develop a relationship for soil erodibility estimation for Chinese soils, a set of soil erodibility values was calculated using soil loss data from natural runoff plots at 13 sites in eastern China. The definition of soil erodibility in relation to the USLE was strictly followed. Comparing these measured values to those estimated using the nomograph method, the method adopted for the EPIC model and the formula of Shirazi and Boersma, we found that all these estimated soil ...

Science.gov (United States)

Enhanced heat transfer in curved rectangular channels depends on at least two geometric factors, the radius of curvature of the duct and the aspect ratio, which is the width/depth ratio of the duct. In this work, an expression for optimum aspect ratio is derived mathematically from a correlation that includes both aspect ratio and bend curvature parameters. Enhancement factors are developed that show optimal, near-optimal, and nonoptimal aspect ratios for curved rectangular ducts. Predicted enhancements are within 25% of published literature results for individual designs, two of which show heat transfer enhancement of 200% over that of a straight duct with turbulent flow. The theoretical maximum enhancement is shown to be about 480% over a straight-duct, turbulent-flow situation. This is not achievable in practice, but near-optimal solutions are achievable, yielding enhancements on the order of 200--300%.

British Library Electronic Table of Contents (United Kingdom)

With the increase of cross-Strait economic activity, the interaction between Taiwanese business people and the Chinese government has gradually changed. As Taiwanese investment grew in volume, so did the number and frequency of contacts between the parties; a more institutionalised form regulating these contacts was established as a result. Nowadays Taiwanese businessmen have become an identifiable factor in Chinese governmental policy implementation; the process also has far-reaching implications. This paper argues that Taiwanese capital has become a Chinese governmental security asset and examines the importance of this factor when discussing conventional government/business interaction. This paper concludes that a superior national interest guides the warm welcome given by the Chinese g...

British Library Electronic Table of Contents (United Kingdom)

Objectives: Acupuncture has served as a major complementary and alternative therapy that supplements conventional medicine and is the subject of growing public interest. This study was conducted to estimate the usage rate of acupuncture as a supplemental treatment in acute ischaemic stroke patients and to identify factors associated with the choice to use this therapy. Methods: Using the registry of stroke patients admitted to an academic medical centre in Korea, the use of acupuncture therapy was recorded and analysed, along with the patients' socio-demographic characteristics, hospital access variables, risk factors for ischaemic stroke and clinical characteristics. The data were analysed using descriptive statistics, chi-square tests and multiple logistic regression analyses. Results: O...

British Library Electronic Table of Contents (United Kingdom)

Abstract Acid-treated cobia (Rachycentron canadum) skin was extracted in a retort (121C) to obtain retorted skin gelatin hydrolysates (RSGHs) containing antioxidant peptides with noticeable antioxidant properties. To improve the antioxidant activity of cobia RSGHs, five processing factors including alkali concentration, alkali pretreatment time, phosphoric acid concentration (PC), water/skin ratio (WS) and retorting time (RT) in RSGH production were screened using a fractional factorial design to identify critical factors. It indicated that PC, WS and RT had significant effects on ,-diphenyl--picrylhydrazyl (DPPH) scavenging by RSGHs. Subsequently, the optimization of PC, WS and RT on the DPPH scavenging of RSGHs was studied using a central composite design to collect data that resulted in...

Energy Technology Data Exchange (ETDEWEB)

The Nuclear Data Interface (NDI) code library and data formats are the standards for multigroup nuclear data at Los Alamos National Laboratory. NDI's analysis, design, implementation, testing, integration, and maintenance required a ten person-year and ongoing effort by the Nuclear Data Team. Their efforts provide a unique, contemporary experience in producing a standard component library. In reflection upon that experience at NDI's decennial, we have identified several factors critical to NDI's success: it addressed real problems with appropriate simplicity, it fully supported all users, it added extra value through the code to the raw nuclear data, and its team went the distance from analysis through maintenance. In this report we review these critical success factors and discuss their implications for future standardization projects.

British Library Electronic Table of Contents (United Kingdom)

The cAMP response element-binding protein (CREB) is a highly conserved transcription factor that integrates signaling through the cAMP-dependent protein kinase A (PKA) in many eukaryotes. PKA plays a critical role in Dictyostelium development but no CREB homologue has been identified in this system. Here we show that Dictyostelium utilizes a CREB-like protein, BzpF, to integrate PKA signaling during late development. bzpF^- mutants produce compromised spores, which are extremely unstable and germination defective. Previously, we have found that BzpF binds the canonical CRE motif in vitro. In this paper, we determined the DNA binding specificity of BzpF using protein binding microarray (PBM) and showed that the motif with the highest specificity is a CRE-like sequence. BzpF is necessary to ...

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The gas-solid reaction and breakthrough curves in the fixed-bed reactor are of great importance, and being influenced by a number of factors makes the prediction of these factors a difficult problem. In this study, the reaction rate between solid sorbents and hydrogen chloride gas at high temperature was first investigated. On the basis of a fixed-bed reactor, the experimental results were analyzed by the shrinking core model of diffusion and surface chemical reaction control. The results showed that reaction rates of two sorbents with hydrogen chloride gas were controlled by the combination of the surface chemical reaction and diffusion of product layers, and the reaction rates nearly keep constant within 15 h of the initial reaction period and then decrease gradually. The results of the breakthrough curves show that solid sorbents in the fixed-bed reactor are capable of reducing the HCl level to near-zero levels at ...

Energy Technology Data Exchange (ETDEWEB)

The results from a hot test, using authentic HLLW solution, of the CTH actinide separation process are reported. The process consists of three solvent extraction cycles for separation of actinides and technetium from reprocessing high level liquid waste, utilizing HDEHP, TBP, and HDEHP in sequence, and an optional step for sorption on inorganic ion exchangers of the fission product content in the process raffinate. In general the process worked according to predictions but a malfunctioning feed pump gave a 10% loss of Pu to one stream. The hot test indicating that U and Pu can be recovered with losses below 0.1% and Am, Cm with a loss below 0.2%. Np and Tc were difficult to follow because of the low activity of /sup 237/Np and because /sup 99/Tc is a pure beta emitter, but the results indicate that also these elements behaved according to predictions, i.e., that recoveries >= 99.8% for Np and >= 97% for Tc can be achieved. For the HLLW ...

Energy Technology Data Exchange (ETDEWEB)

This report presented an analysis of incidents gathered by the Canadian upstream oil and gas industry committee in relation to explosive atmospheres in wellbores, vessels, tanks, and piping systems. The aim of the report was to develop industry recommended practices for oil and gas industry fires and explosions. Two accident theory models were used to set out the relationships between hazards, defenses, and losses. Three levels of defenses were identified based on organizational, local workplace, and human factors. An organizational responsibility approach was used to examine the activities of key people with the system. Incidents were analyzed based on an expanded fire triangle used to identify fire and explosion hazards. The study showed that the ignition of hydrocarbons into the air was a factor in nearly 50 per cent of the incidents. A lack of understanding of liquid-hydrocarbon properties was ...

Science.gov (United States)

The effects of variable hardness, pH, alkalinity, humics, and suspended clay on the chemical speciation of copper and its toxicity to fathead minnow larvae in Lake Superior water were investigated. Two proposed methods (toxicity factors and chemical speciation) for predicting LC50 values in specific natural waters from laboratory toxicity data and the average site specific values of general water quality parameters were evaluated. The accuracy of the cupric ion-selective electrode in determining CU/sup +2/ activities in ambient and chemically altered Lake Superior water was also determined.

Science.gov (United States)

This paper reports that, to obtain better simulation results for a Canada deuterium uranium (CANDU) reactor operation, a new simulation method is developed that uses actual detector readings as a correction factor. Detector readings from a CANDU reactor are used to correct the calculated flux distribution during core calculation iterations. A suitable function is found to describe the relationship between the detector flux and the fluxes of mesh points around the detector. The new simulation method is tested by performing numerical calculations for the Wolsung reactor (a CANDU-600). The results show that the new method predicts the core state more accurately with fewer iterations.

British Library Electronic Table of Contents (United Kingdom)

In a study of hitchhiking or contaminating insect pests on international cargo aircraft at Miami International Airport from 1998 to 1999, it was found that contamination rates were greatest, 23%, on cargo flights from Central America and much lower, near 5%, on flights from all other regions. We reanalyzed the study data to test for associations between contaminated flights and factors such as season, cargo type, and time of departure (night or day), and developed probabilistic models for predicting insect pest arrivals by region and pest risk levels. Significant (P

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We investigate the quantum cosmology of spatially homogeneous models with compact spatial sections admitting a u(2) isometry algebra. The metric ansatz in these models is that of Bianchi type IX with two scale factors set to be equal. We apply the Hartle-Hawking no-boundary path integral prescription and find the semi-classical contributions to the wave function. Exact formulae are obtainable for certain contributions and otherwise the limits of large and small anisotropy (for the pure vacuum case) and large spatial volume or small anisotropy (for the case with a positive cosmological constant) are considered. For the pure vacuum case we find no rapidly oscillating semiclassical components in the wave function, and hence do not recover lorentzian space-time as a prediction of the no-boundary proposal. For the case with a cosmological constant the wave function does contain rapidly oscillating components and thus predicts ...

CERN Document Server

We examine the effect of a threshold bias on the power spectrum and the bispectrum in an ensemble of numerical simulations (Gaussian initial perturbations with power law spectra P(k) \\sim k^n, n=+1, 0, -1, -2) and compare our results with theoretical predictions. Our simulations are evolved sufficiently that on the scale where we apply the threshold the rms fluctuation has developed significantly into the nonlinear regime. Thus, predictions based on perturbation theory do not necessarily apply. Nevertheless, we find our results for the power spectrum, biased power simply amplified by a numerical factor, follow predicted trends, far beyond the regime where perturbation theory is expected to be valid. We find that the biased bispectrum continues to follow the so-called hierarchical form, with reduced three-point amplitude Q \\approx 1 in the strongly nonlinear regime, independent of initial spectrum. In ...

International Nuclear Information System (INIS)

Debris coolability in the lower plenum of the reactor pressure vessel is an important factor for evaluation of debris in-vessel retention. The debris coolability analysis module is developed for the accurate prediction of the safety margin of the present reactor vessels in a severe accident. The module calculates debris spreading and cooling through melting and solidification in combination with a temperature distribution and failure evaluation of the vessel wall. Debris spreading is solved by the explicit method on a quasi-three-dimensional scheme and debris coolability is solved on the basis of natural convection analysis. The calculation for spreading is compared with a water spreading experiment on the floor and the calculation for coolability is compared with a n-octadecane melting experiment in a rectangular vessel. The comparisons show capabilities for predictions of spearhead transportation in the debris spreading ...

British Library Electronic Table of Contents (United Kingdom)

The effective integration of technology into the teaching and learning of mathematics remains one of the critical challenges facing contemporary tertiary mathematics. This article reports on some significant findings of a wider study investigating the use of technology in undergraduate mathematics. It first discusses a taxonomy developed to describe and compare technology use within individual courses and departments that identifies a complex range of factors, summarized under six defining characteristics of an integrated technology mathematics curriculum (ITMC). An instrument for a simple comparison of technology use employing the elements of this taxonomy is provided. It then presents evidence gathered from an observational study of technology implementation at The University of Auckland...

Energy Technology Data Exchange (ETDEWEB)

Projected scenarios for the proposed Yucca Mountain repository include significant periods of time when high relative humidity atmospheres will be present, thus the reaction processes of interest will include those known to occur under these conditions. The ideal natural analog for the proposed Yucca Mountain repository would consist of natural borosilicate glasses exposed to expected repository conditions for thousands of years; however, the prospects for identifying such an analog are remote, but an important caveat for using natural analog studies is to relate the reaction processes in the analog to those in the system of interest, rather than a strict comparison of the glass compositions. In lieu of this, identifying natural glasses that have reacted via reaction processes expected in the repository is the most attractive option. The goal of this study is to quantify molecular water diffusion in the natural analogs obsidian and tektites. ...

International Nuclear Information System (INIS)

The International Atomic Energy Agency has initiated a co-ordinated research programme on implementation of base-isolation for nuclear structures. This paper discusses two areas relevant to modelling elastomeric base-isolators. These are the use of simplified models to predict the response of isolated structures to earthquake inputs and finite element analysis for calculating the stress distributions within the isolators. In the former, a curvilinear hysteretic model of the high damping natural rubber able to accommodate the stiffening of the rubber at large shear deflections is presented. Its predictions of structural accelerations and bearing displacement produced by design earthquakes and those above the design level are compared with those using a linear spring and dashpot model. A comparison has been made between two finite element analyses using MARC and ABAQUS of the force-deformation behaviour of a single disc of rubber bonded on both ...

International Nuclear Information System (INIS)

The response of MOS capacitors to low- and medium-energy x-ray irradiation is investigated as a function of gate material (TaSi or Al), oxide thickness, and electric field. Measured device response is compared with predictions based on discrete ordinates and Monte Carlo code simulations of dose enhancement effects, coupled with recent estimates of electron-hole recombination in MOS oxides. In comparisons of 10-keV x-ray and Co-60 irradiations of Al-gate MOS capacitors at an oxide electric field of 1 MV/cm, it is found that predictions and experiments agree to within better than 20 percent for oxide thicknesses ranging from 35 to 1060 nm. For capacitors having TaSi/Al gates, predictions and experiments agree to within better than 30 percent at 1 MV/cm, with the largest differences occurring for 35-nm gate oxides. At other electric fields, the disagreement between experiment and prediction increases ...

International Nuclear Information System (INIS)

Magnetically driven non-stationary acceleration of jets in active galactic nuclei results in the leading parts of the flow being accelerated to much higher Lorentz factors than in the case of steady-state acceleration with the same parameters. The higher Doppler-boosted parts of the flow may dominate the high-energy emission of blazar jets. We suggest that highly variable GeV and TeV emission in blazars is produced by the faster moving leading edges of highly magnetized non-stationary ejection blobs, while the radio data trace the slower-moving bulk flow. Thus, the radio and gamma-ray emission regions have different, but correlated, Doppler factors. High-energy emission is generated, typically within the optically thick core, in the outer parts of the broad-line emission region, avoiding the radiative drag on the faster parts of the flow. The radio emission should correlate with the gamma-ray emission, delayed with frequency-dependent time lag ...

Energy Technology Data Exchange (ETDEWEB)

The deactivation rate of a resid hydrotreating catalyst is determined by a complex set of factors involving both chemical and physical changes in the catalyst structure. The various chemical changes that are associated with resid conversion involve thermal and catalytic steps of relatively large molecular weight species with the overall rates significantly affected by mass transfer limitations. The deposition of coke and the variation in the effective promoter level by the accumulation of metals deposited from the resid are the principal factors governing deactivation. The relative importance of mass transfer restrictions on activity and catalyst deactivation can be observed in studies where the average pore diameter of the catalyst has been varied. Several models have been proposed to characterize the deactivation of resid hydroprocessing catalysts. In this paper, the authors discuss some accelerated aging tests with a relatively large pore ...

British Library Electronic Table of Contents (United Kingdom)

The levels of General Transcription Factor (TF) IIA were examined during mammalian brain development and in rat embryo fibroblasts and transformed cell lines. The large TFIIA subunit paralogues ab and t are largely produced in unsynchronized cell lines, yet only TFIIA ab is observed in a number of differentiated tissue extracts. Steady-state protein levels of the TFIIA t, ab, and g subunits were significantly reduced when human embryonal (ec) and hepatic carcinoma cell lines were stimulated to differentiate with either all-trans-retinoic acid (ATRA) or sodium butyrate. ATRA-treated NT2-ec cells required replating to induce a neuronal phenotype and loss of detectable TFIIA t and g proteins. High levels of TFIIA t, ab, and g and Sp factors were identified in extracts from human fetal and rat...

Energy Technology Data Exchange (ETDEWEB)

Attacks by herbivorous insects reduce biomass production in willow plantations. The long-term goal of our research is to develop sustainable plant protection against these insect pests. Two lines of research are pursued. The first concentrates on identifying factors involved in the regulation of leaf-eating beetles. These insects vary in density among plantations, sometimes reaching outbreak levels resulting in complete defoliation. Mortality factors of eggs and larvae in plantations with low and high beetle densities have been investigated. The importance of plant resistance has also been investigated. The second line of research considers the mechanisms behind an earlier demonstrated resistance in certain willow clones against a gall midge. By using molecular techniques we have searched for markers of resistance. Promising results have been found concerning so called PR proteins; in particular chitinase seems to be ...

International Nuclear Information System (INIS)

Many assays for oncogenic transformation have been developed ranging from those in established rodent cell lines where morphological alteration is scored, to those in human cells growing in nude mice where tumor invasiveness is scored. In general, systems that are most quantitaive are also the least relevant in terms of human carcinogenesis and human risk estimation. The development of cell culture systems has made it possible to assess at the cellular level the oncogenic potential of a variety of chemical, physical and viral agents. Cell culture systems afford the opportunity to identify factors and conditions that may prevent or enhance cellular transformation by radiation and chemicals. Permissive and protective factors in radiation-induced transformation include thyroid hormone and the tumor promoter TPA that increase the transformation incidence for a given dose of radiation, and retinoids, selenium, vitamin E, and ...

International Nuclear Information System (INIS)

Intracapsular femoral neck fractures remain unsolved fractures even after improvement in techniques of diagnosis and internal fixation. Individuals who sustain displaced femoral neck fractures are at high risk of developing avascular necrosis and non-union. Although several methods for predicting the viability of femoral head have been reported, they are not effective or widely used because of unreliability, potential complications and technical difficulties. Dynamic MRI was introduced in the recent past as a simple, non-invasive technique to predict the femoral head viability after the femoral neck fractures. In this study role of dynamic MRI was studied in 30 patients with 31 intracapsular femoral neck fractures. Fractures were divided in to three types according to dynamic curve patterns on MRI evaluation and were followed up for 6 months to 2 years to observe the final outcome. Sensitivity, Specificity and the Accuracy of dynamic MRI in ...

Energy Technology Data Exchange (ETDEWEB)

An overview is provided of an evolving atomistic and kinetic model of semiconductor growth that unifies the main features of strain relaxation in low and high lattice misfit heteroepitaxy. The model reveals a kinetic pathway for dislocation formation during growth with little or no energy cost at low misfits, thus providing a way out of the longstanding dilemma of too high dislocation nucleation energies predicted by classical theories of the equilibrium behavior of a fixed number of particles at low misfits. The essential kinetic process underlying the model are identified on the basis of comparison of the predictions of kinetic Monte-Carlo simulations of growth with real-time or in-situ data obtained in such experiments as reflection high-energy electron diffraction (RHEED) and scanning probe microscopy (SPM). Relative significance of these atomistic kinetic processes is shown to naturally lead to strain relaxation via ...

International Nuclear Information System (INIS)

An uncertainty decrease is an very important issue for enhancing risk-informed (RI) activities worldwide. Especially, a relatively large uncertainty in a level-2 (L2) PSA risk compared with level-1 internal PSA risk has been a bottleneck problem in the RI application to the extent of a severe accident management. According to the ASME PRA standard in which sources of an uncertainty to capture a category-II RI (= Option 2) capability are listed, an uncertainty analysis which identifies the key sources of an uncertainty and includes sensitivity studies for dominant contributors to LERF (Large Early Release Frequency) needs to be provided. To solve these problems, USNRC have developed the 'SPAR-LERF' model related to the L2 RI application and 'L2 uncertainty assessment and improvement' work is being taken as a main PSA2 topic of the SARNET (Severe Accident Research Network of Excellence) program in Europe by OECD/NEA. Domestically, a mid/long-term R and D is being ...

Energy Technology Data Exchange (ETDEWEB)

The giant resonance region in several nuclei in A {>=} 90 have been re-measured using 240 MeV {alpha} particle scattering with a detector provides that both horizontal and vertical angles. Slice analyses with multipole fits were performed and strength due to both low and high energy components of the isoscalar giant dipole resonance (ISGDR) was identified. E1 strengths for the high energy component corresponding to 70{+-}15%,68{+-}15% and 67{+-}14% of the isoscalar E1 energy-weighted sum rule were identified, with centroid energies of 26.3{+-}0.6 MeV, 24.7{+-}0.6 MeV and 21.7{+-}0.6 MeV for {sup 90}Zr, {sup 144}Sm and {sup 208}Pb, respectively. The centroid of the high energy component of the strength distribution is in closer agreement with the microscopic prediction generated using compressibilities obtained from the isoscalar giant monopole resonance data.

CERN Document Server

Most of the presently identified exoplanets have masses similar to that of Jupiter and therefore are assumed to be gaseous objects. With the ever-increasing interest in discovering lower-mass planets, several of the so-called super-Earths (i.e., with masses in the interval 1 M_earth < M < 10 M_earth), which are predicted to be rocky, have already been found. Here we report the possible discovery of a planet around the M-type star GJ 436 with a minimum mass of 4.8+/-0.6 M_earth and a true mass of ~5 M_earth, which makes it the least massive planet around a main-sequence star found to date. In contrast with other discoveries, the planet is identified from its perturbations on an inner Neptune-mass transiting planet (GJ 436b), by pumping eccentricity and producing secular variations in the orbital inclination. Analysis of published radial velocity measurements indeed reveals a significant signal corresponding to an ...

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

International Nuclear Information System (INIS)

Transmission nuclear resonance fluorescence measurements were made on targets consisting of Pb and depleted U with total areal densities near 86g/cm"2. The "2"3"8U content in the targets varied from 0% to 8.5% (atom fraction). The experiment demonstrates the capability of using transmission measurements as a non-destructive technique to identify and quantify the presence of an isotope in samples with thicknesses comparable to the average thickness of a nuclear fuel assembly. The experimental data also appear to demonstrate the process of notch refilling with a predictable intensity. Comparison of measured spectra to previous backscatter "2"3"8U measurements indicates general agreement in observed excited states. Evidence of two new "2"3"8U excited states and possibly a third state have also been observed.

Energy Technology Data Exchange (ETDEWEB)

Progress in the worldwide capability of predicting the convective energy loss from solar central receivers is reviewed. The significant advances in the past three years have been in experimental areas. Baseline measurements of the convective heat transfer from large high-temperature surfaces, e.g., a flat plate and a cubical cavity, have been completed and empirical correlations have been obtained. Theoretical modeling activities have not kept pace with the experimental advances, however. Currently, the primary theoretical emphasis is the development and testing of turbulence models suitable for buoyant flows. Three major needs have been identified: the measurement of convective energy losses from operating solar central receivers; the continued development of theoretical models in spite of the relatively slow progress to date; and the quantification of the effects of atmospheric turbulence.

British Library Electronic Table of Contents (United Kingdom)

Climex climate-matching and inferential-modelling was used to examine the naturalisation potential of genetically modified and non-transgenic Upland Cotton (Gossypium hirsutum variety hirsutum) in Australia north of latitude 22degreeS. The Climate-Match (CM) function was used to identify locations in north-east Australia where climate matches (CM Index>0.7) the experimental sites of Eastick [Eastick, R., 2002. The Potential Weediness of Transgenic Cotton in Northern Australia. Northern Territory Department of Business, Industry and Resource Development Technical Bulletin No. 305 (Internet resource: http://cotton.pi.csiro.au/Assets/PDFFiles/TB3051.pdf)] in north-west Australia. Most of Australia north of 22degreeS had climate matching one or more of the sites of Eastick (2002), locations wh...

Energy Technology Data Exchange (ETDEWEB)

The prospects for the low-aspect-ratio (A) tokamak to fulfill the requirements of viable fusion power plants are considered relative to the present status in data and modeling. Desirable physics and design features for an attractive Blanket Test Facility and power reactors are estimated for low-A tokamaks based on calculations improved with the latest data from small pioneering experiments. While these experiments have confirmed some of the recent predictions for low-A, they also identify the remaining issues that require verification before reliable projections can be made for these deuterium-tritium applications. The results show that the low-A regime of small size, modest field, and high current offers a path complementary to the standard and high A tokamaks in developing the full potential of fusion power.

Energy Technology Data Exchange (ETDEWEB)

During the present project the mechanisms of generation of low frequency noise (LFN) for upwind rotors has been investigated. A 3.6 MW turbine has been simulated with a noise prediction model from NASA in US. Running the model on this turbine a number of important turbine design parameters with influence on the LFN have been identified as well as other parameters not linked to the turbine design. Of important parameters can be mentioned 1) rotor rotational speed, 2) blade/tower clearance, 3) rotor configuration - upwind/downwind, 4) unsteadiness/turbulence in inflow. Further, the directivity characteristics of LFN has been computed as well as reduction in noise as function of distance from the turbine. In general low levels of LFN has been computed for the upwind rotor in standard configuration. (au)

British Library Electronic Table of Contents (United Kingdom)

Abstract: The cane toad (Bufo marinus), a large, toxic, American anuran, was introduced to Australia in 1935. Populations of many of Australia's reptiles (snakes, varanid lizards, crocodiles) and carnivorous mammals (dasyurid marsupials) have declined because these predators are killed by the toad's powerful toxins. In contrast to these well-studied species, little is known about the cane toads impacts on Australian birds. We reviewed published and unpublished data on behavioral interactions between Australian avian predators and cane toads and collated distributional and dietary information to identify avian taxa potentially at risk from cane toad invasion. Cane toads are sympatric with 172 frog-eating bird species in Australia, and an additional 8 bird species overlap with the predicted ...

British Library Electronic Table of Contents (United Kingdom)

In most current recommender systems, the goal to accurately predict what people want leads to the tendency to recommend popular items, which is less helpful in revealing user?s personality, especially to new users. In this paper, we propose a heuristic music recommendation method for niche market by focusing on how to identify user?s personality as soon as possible. Instead of trying to improve algorithm's performance on new users by recommending the most popular items, we work on how to make them ?familiar? with the system earlier. The method is more suitable for brand-new users, and gives a hint to solve the cold start problem. In real applications it is better to combine it with a traditional approach.

Energy Technology Data Exchange (ETDEWEB)

For 170 years, scientists have attempted to explain why consistent temporal patterns of death are observed among individuals within populations. Historical efforts to identify a {open_quotes}law of mortality{close_quotes} from these patterns ended in 1935 when it was declared that such a law did not exist. These empirical tests for a law of mortality were constructed using mortality curves based on all causes of death. We predicted that patterns of mortality consistent with the historical concept of a law would be revealed if mortality curves for species were constructed using only senescent causes of death. Using data on senescent mortality for laboratory animals and humans, we demonstrate that patterns of mortality overlap when compared on a biologically comparable time scale. These results are consistent with the existence of a law of mortality following sexual maturity as asserted by Benjamin Gompertz and Raymond Pearl. The societal, ...

Energy Technology Data Exchange (ETDEWEB)

Spiral orbit tribometry friction tests performed on Ni-rich Ni55Ti45 titanium ball bearings indicate that this alloy is a promising candidate for future aerospace bearing applications. Microstructural characterization of the bearing specimens was performed using transmission electron microscopy and energy dispersive spectroscopy, with NiTi, Ni4Ti3, Ni3Ti, and Ni2Ti4Ox phases identified within the microstructure of the alloy. Density functional theory was applied to predict the electronic structure of the NixTiy phases, including the band structure and site projected density of states. Ultraviolet photoemission spectroscopy was used to verify the density of states results from the density functional theory calculations, with good agreement observed between experiment and theory.

Energy Technology Data Exchange (ETDEWEB)

A comprehensive review was conducted of primary helium coolant chemistry data, based on current and past operating histories of helium-cooled, high-temperature reactors (HTGRs), including the Fort St. Vrain (FSV) HTGR. A reference observed FSV reactor coolant environment was identified. Further, a slightly drier expected FSV coolant chemistry was predicted for reactor operation at 100% of full power. The expected environment was compared with helium test environments used in the US, United Kingdom, Germany, France, and Japan. Based on a comprehensive review and analysis of mechanical property data reported for Alloy 800 tested in controlled-impurity helium environments (and in air when appropriate for comparison), an assessment was made of the effect of FSV expected helium chemistry on material properties of alloy 800, with emphasis on design properties of the Alloy 800 material utilized in the FSV steam generators.

Science.gov (United States)

This paper focuses on a factorial-based design strategy. The approach provides an efficient and statistically reliable means for assessing the influence of multivariable effects. It is applied to the detection and evaluation of damage in impacted composite sandwich panels. The experimental results obtained from this test strategy are utilized to form an empirical response function. The resulting polynomial relates damage area to residual compression strength at values of independent variables for which testing did not occur. The response function also identifies nonlinear interaction effects of key variabes that cannot be easily ascertained by traditional single-variable test strategies. Independent variables evaluated include core thickness, number of face sheet plys and impact energy. The methodology presented allows the designer to predict with more confidence the damage tolerance of a composite material component, and the analyst to more ...

Energy Technology Data Exchange (ETDEWEB)

Calculating work-function modifications for flat-lying conjugated molecules on extended metal surfaces using density functional theory (DFT) is an extremely resource intensive task. This prevents fast screening of new molecules for their potential to optimize metal work functions for good electron or hole injection in organic electronic devices. We present a semi-classical model, which avoids that problem. This is achieved by identifying the dominant processes occurring at the interface between metal and adsorbate in the pinning-regime, which are then parameterizing their description using band-structure DFT calculations for a small training set With the resulting interdependent equations at hand, only simple gas-phase calculations are needed to predict the work-function changes induced by new molecules. The model is tested for ten molecules on three different metal surfaces, where it shows excellent agreement with photoelectron spectroscopy ...

Energy Technology Data Exchange (ETDEWEB)

As the penetration of wind energy continues to increase around the world, with a trend towards large utility-scale wind farms (greater than 100 MW), effective wind energy forecasting will become increasingly important. Previous work by GH has estimated the trading benefit of high quality short-term forecasting to be EUR 7/MWh. Depending on market conditions, for a 100 MW wind farm with a capacity factor of 30%, this equates to an estimated annual trading benefit of up to EUR 1.8m. To date, a number of studies have focused on the mathematical modelling techniques for forecasting the production from wind farms, looking predominantly at the task of predicting the meteorological conditions at the site. This paper focuses on the final stage of the forecasting process, conversion from a meteorological forecast to a power production forecast. This challenge is particularly significant for utility-scale wind farms. The main body of research in ...

Energy Technology Data Exchange (ETDEWEB)

The five thermal-hydraulic concepts chosen for conceptual study of advanced PWR systems have been studied as follows: (1) Critical Heat Flux in passive PWR Conditions: review of previous works (various of correlations, analysis of parametric trends) on CHF, assessment and improvement of CHF prediction models for round tubes, development of the prediction model on bundle CHF with considering the correction factor calculated from the tube data base, design and construction of the intermediate-pressure CHF experimental loop, extension of CHF data base by performing the experiments at low-flow, and low-quality conditions (2) Passive Cooling Concepts for Concrete Containment Systems: Selection of the external condenser by comparing and reviewing between passive cooling concepts for concrete containment system concepts, survey and review of previous studies (theoretical mechanism of condensation heat transfer and effect of ...

Energy Technology Data Exchange (ETDEWEB)

The problem of buried steelwork in cargo hold insulation has been investigated by several using empirical methods. These efforts have resulted in correction factors that serve as a useful aid in the complex task of estimating the K-value of a ship`s cargo holds for the correct dimensioning of the refrigeration plant. Today, the advent of the digital computer has established numerical methods of analysis as a common working tool among practicing engineers. For estimating the flow in cases of buried steelwork that cannot be handled by correction factors, this is an effective approach. This study is an analytical/numerical investigation of the effect that buried steelworks have on the heat leakage across cargo hold walls. It aims at providing enlightenment on the physical significance of the parameters influencing the problem and developing practically simple methods for predicting the heat leakage across the hold walls. The ...

Science.gov (United States)

Background: Accountability demands are increasingly pushing school leaders to explore more data and do more sophisticated analyses. Data-driven decision making (DDDM) has become an emerging field of practice for school leadership and a central focus of education policy and practice. Purpose: This study examined principals' DDDM practices and identified the factors influencing DDDM using the theoretical frame of information use environments. Participants: Participants were 183 public high school principals in a Midwestern state. Research Design: The research design was cross-sectional survey research. Data Collection and Analysis: Survey instruments were developed and administered to principals. Structural equation modeling was conducted to determine what factors significantly affect principals' DDDM practices in different leadership dimensions. Findings: Principals used data more frequently in instructional and organization ...

International Nuclear Information System (INIS)

Up to the present, the generic values of the Common cause failure (CCF) event parameters have been used in most PSA projects for the Korean NPPs. However, the CCF analysis should be performed with plant specific information to meet Category II of the ASME PRA Standard. Therefore, we estimated the Alpha factor parameters of the emergency diesel generator (EDG) for Ulchin Unit 3 by using the International Common-Cause Failure data Exchange (ICDE) database. The ICDE database provides the member countries with only the information needed for an estimation of the CCF parameters. The Ulchin Unit A3, pressurized water reactor, has two onsite EDGs and one alternate AC (AAC) diesel generator. The onsite EDGs of Unit 3 and 4 and the AAC are manufactured by the same company, but they are designed differently. The estimation procedure of the Alpha factor used in this study follows the approach of the NUREG/CR-5485. Since we did not find any qualitative ...

International Nuclear Information System (INIS)

This publication identifies conditions which affect (either increase or decrease) public concern for and political acceptance of the development and implementation of programmes for geological disposal of long lived radioactive waste. It also looks at how interested citizens can be associated in the decision making process in such a way that their input enriches the outcome of a more socially robust and sustainable solution. The publication also considers how to optimize risk management, addressing the needs and expectations of the public and of other relevant stakeholders. Factors of relevance for societal acceptance conditions are identified for the different stages of a repository programme and implementation process, from policy development to the realization of the repository itself. Further, they are described and analysed through case studies from several countries, illustrating the added value of broadening the ...

Energy Technology Data Exchange (ETDEWEB)

In the development of the man-made island siting technology of nuclear power plants, assessing the stability of the seawall against large ocean waves and earthquakes is indispensable. Concerning with the seismic stability of the seawall, prediction of the deformation like sliding and settlement of the seawall during earthquake including the armour units in front of the caisson becomes important factor. For this purpose, the authors have developed the two-dimensional DEM-FEM coupled analysis method (SEAWALL-2D) to predict the deformation of the seawall covered with the armour units during earthquake. In this method, movements of the armour units are calculated in DEM analysis part and deformation of the caisson, rubble moundsand seabed and back fill are calculated in FEM analysis part taking the nonlinearity of the soil materials based on the effective stress into account. Numerical simulations of dynamic centrifuge model ...

CERN Document Server

Empirical birthrate estimates for pulsar binaries depend on the fraction of sky subtended by the pulsar beam: the pulsar beaming fraction. This fraction depends on both the pulsar's opening angle and the misalignment angle between its spin and magnetic axes. Previous estimates use the average value for only two pulsars, i.e. PSRs B1913+16 and B1534+12. We explore how birthrate predictions depend on assumptions about opening angle and alignment, using empirically-motivated distributions to define an effective beaming correction factor, f_{b,eff}. For most known pulsars, we expect f_{b,eff} to be less than 6. We also calculate f_{b,eff} for PSRs J0737-3039A and J1141-6545, applying the currently available constraints for their beam geometry. Our median posterior birthrate predictions for tight PSR-NS binaries, wide PSR-NS binaries, and tight PSR-WD binaries are 89/Myr, 0.84/Myr, and 34/Myr, respectively. For pulsars with spin ...

International Nuclear Information System (INIS)

This paper presents an overview of issues related to surface water contamination arising from uranium mining activities in the Alligator Rivers Region (ARR) of northern Australia, and a program of research and monitoring that must assess the potential and actual effects on ecosystem and human health. The program of assessing effects on aquatic ecosystems involves a four-tiered approach including the derivation of local water quality guideline trigger values, direct toxicity assessment of mine waters prior to their release, creekside or in situ monitoring for early warning of adverse effects during mine water release, and longer-term monitoring of macroinvertebrate and fish communities. Bioaccumulation in aquatic biota is also assessed, and is an issue of importance not only to ecosystem health, but also to the health of local Aboriginal people. The aquatic animals they consume represent potential sources of radiological dose, and as a result, a major component of the program to assess ...

Energy Technology Data Exchange (ETDEWEB)

This report describes the results of EPRI Program S404-28, titled Experimental Modeling of Eddy Current Response'', conducted by the Westinghouse Science and Technology Center (STC). The Westinghouse STC demonstrates that its mercury modeling technique provides an unique bridge between steam generator eddy current field inspection conditions and predictions obtained using recently developed analytical models. The mercury modeling technique was used systematically to explore factors which contribute to primary water stress corrosion cracking (PWSCC) sizing inaccuracy, including probe design, coil excitation frequency, crack length, and crack morphology. Two new proposed techniques for inverting crack lengths from eddy current data are compared with the technique commonly used in field data analysis for PWSCC. The performance of uniform field eddy current probes is compared with the performance of pancake coil probe designs, and ...

Science.gov (United States)

The Process Waste Treatment Plant (PWTP) at the Oak Ridge National Laboratory is designed to remove radioactive contaminants, principally {sup 90}Sr, from process wastewater. Planned upgrades to the PWTP will use chabazite zeolite columns. Pilot-scale studies have shown that mass transfer zone lengths increase from 10 to about 30 cm as the superficial velocity increases from 5.5 to 22 cm/min. Calculations with a multicomponent equilibrium model showed that the distribution coefficient for strontium remains essentially constant over the process conditions, suggesting that a simple kinetic model (the Rosen long-bed solution) should adequately represent breakthrough behavior. Using a distribution coefficient of 4.87 L/g predicted by the equilibrium model, good agreement was found between experimental breakthrough curves and those calculated with the Rosen solution. This model allows prediction of bed depths and cycle times necessary to achieve the ...

Science.gov (United States)

This article provides an historical look at how programs and practices for students with emotional or behavior disorders (E/BD) have been evaluated since 1964, leading to a codified, although not universally recognized, set of recommendations for evaluating best practices for students with E/BD set out by The Peacock Hill Working Group (1991). The authors contend that, in addition to the programmatic features of best practice, the addition of the quality indicators and standards for research in special education add a critical dimension for examining the quality of the scientific research of identified best practices. Taken together, these set of recommendations and quality indicators represent the state of the art in program evaluation for best practice and programs for students with E/BD. The goal of this article is to outline the current recommendations and apply them to current behavior intervention practices to identify how well the field ...

Energy Technology Data Exchange (ETDEWEB)

This report summarizes the major features of the advisory tool `TUNDTEMP`, developed to act as a decision support in the continuous steel casting process. `TUNDTEMP` provides a means to predict abnormal phenomena of temperature origin in the casting that may be difficult to foresee in practical situations. The heart of the system is a semi-empirical calculation model that yields an estimate of the evolution of the tundish temperature of the liquid steel on the basis of a few important casting factors. The user interface of the system is to a large extent based on the visual presentation of the simulated results. The system also contains an optional rule based mechanism that provides assistance in the result interpretation and, if wished, linguistically formulates action recommendations. A separate program has been built for the tuning of the calculation model and for maintenance of the system. At the end of the report, the different tuning ...

British Library Electronic Table of Contents (United Kingdom)

The long-term health consequences of war service remain unclear, despite burgeoning scientific interest. A longitudinal cohort study of a random sample of Australian Vietnam veterans was designed to assess veterans' postwar physical and mental health 36 years after the war (2005-2006) and to examine its relation to Army service, combat, and post-traumatic stress disorder (PTSD) assessed 14 years previously (1990-1993). Prevalences in veterans (n = 450) were compared with those in the Australian general population. Veterans' Army service and data from the first assessments were evaluated using multivariate logistic regression prediction modeling. Veterans' general health and some health risk factors were poorer and medical consultation rates were higher than Australian population expectatio...

International Nuclear Information System (INIS)

High-K states in the region of 177Lu have been studied using multi-nucleon transfer reactions with 136Xe beams and Gammasphere. Results include identification of the predicted 5-quasiparticle K#pi# = 39/2 - isomer in 177Lu, a 7-quasiparticle K#pi# = 49/2 + isomer in 179Ta with an anomalously fast decay, and numerous other examples in a range of Yb close to stability. The results are discussed in the context of the expectations for multi-quasiparticle states near Z = 72 and the factors which may both govern isomer formation and also give an insight into K-purity, specifically chance degeneracies, and statistical mixing above the yrast line.

Energy Technology Data Exchange (ETDEWEB)

An assessment was undertaken of the risk of liver cancer in the USA associated with aflatoxin ingestion from peanuts. Both laboratory-animal data and epidemiological data collected from the scientific literature and several prominent mathematical extrapolation techniques were used. Risk estimates differed by a factor of greater than 1000 when the extrapolated results of three selected animal studies were analysed. Dose-response data for the male Fischer rat, the most sensitive mammalian species studied, produced an estimate of 158 cases of liver cancer per year in the USA at current levels of aflatoxin exposure. An estimate of 58 annual cases was predicted on the basis of epidemiological data of populations in Africa and Thailand.

Science.gov (United States)

This study examined the psychometric properties of the Anti-fat Attitudes Scale (AFAS), a 5-item instrument developed by the authors to measure negative attitudes toward overweight individuals. A total of 4 studies were conducted among Canadian adolescents (n = 1,452) and university students (n = 424). Results suggested that the AFAS possessed a unidimensional factor structure and satisfactory reliability for both men and women. As predicted, men obtained higher scores than women on the AFAS, and antifat attitudes were positively associated with authoritarianism, homonegativity, and political conservatism. Participants who were overweight had lower scores on the AFAS than participants who were thin or average weight. Responses on the AFAS did not appear to be contaminated by social desirability bias. PMID:10457760

British Library Electronic Table of Contents (United Kingdom)

We present an innovative approach to estimating residential irrigation water demand for a large metropolitan area using GIS data, weather station data, and a water budget modeling approach commonly used by plant scientists and landscape management professionals. An important question addressed by our study is how a growing urban forest affects the overall irrigation water demand of a semiarid metropolitan area. To estimate the amount of water required by residential landscaping, we consider water demand to be a function of the areal extent of residential landscaping (i.e. tree/shrub or turf grass), the water-loss rate for different landscaping types, the efficiency with which the landscape is irrigated, and local climatic factors (i.e. reference evapotranspiration and precipitation). We es...

CERN Document Server

We study 1-loop effects for massless Dirac fields in two spatial dimensions, coupled to homogeneous electromagnetic backgrounds, both at zero and at finite temperature and density. In the case of a purely magnetic field, we analyze the relationship between the invariance of the theory under large gauge transformations, the appearance of Chern-Simons terms and of different Berry's phases. In the case of a purely electric background field, we show that the effective Lagrangian is independent of the chemical potential and of the temperature. More interesting: we show that the minimal conductivity, as predicted by the quantum field theory, is the right multiple of the conductivity quantum and is, thus, consistent with the value measured for graphene, with no extra factor of pi in the denominator.

Energy Technology Data Exchange (ETDEWEB)

M-shell X-ray production cross sections for the light rare-earth elements of {sup 68}Er, {sup 7}Yb and {sup 71}Lu have been measured for incident {sup 4}He{sup +} ions in the energy range from 0.75 to 6 MeV. The measured X-ray production cross sections are compared to the predictions of the First Born approximation, the ECPSSR theory and the ECUSAR theory. A comparison of the ytterbium M-shell X-ray production cross sections with these theories is made for two different sets of fluorescence yields and Coster-Kronig factors that are further modified for multiple ionization.

International Nuclear Information System (INIS)

Measurements are made on the principal magnetic susceptibilities and anisotropies of praseodymium selenate octahydrate single crystals in the temperature range 90 to 300 K. Although the effective magnetic moment is close to the free ion value, the anisotropy is quite high at room temperature. A least sequares fit of the Curie-Weiss law to the observed average susceptibility yields -36.5 K as the paramagnetic Curie temperature. An analysis of the results with a crystal field (CF) of D_4 symmetry, explains the observed results quite well. The CF and the spin-orbit interaction matrix is block diagonalized in the complete 33 dimensional basis of the "3H term in order to obtain the Stark energies and their eigenstates. Intermediate coupling effects are also considered. The ground state being a singlet, the g-factors are absent. Some predictions on the electronic heat capacity and the electronic quadrupole splitting are made in the light of the ...

Energy Technology Data Exchange (ETDEWEB)

The role of shear in determining the ideal MHD stability properties of tokamaks is discussed. In particular, we assess the effects of low shear within the plasma upon pressure-driven modes. The standard ballooning theory is shown to break down, as the shear is reduced and the growth rate is shown to be an oscillatory function of n, the toroidal mode number, treated as a continuous parameter. The oscillations are shown to depend on both the pressure and safety-factor profiles. When the shear is sufficiently weak, the oscillations can result in bands of unstable n values which are present even when the standard ballooning theory predicts complete stability. These instabilities are named ''infernal modes.'' The occurrence of these instabilities at integer n is shown to be a sensitive function of q-axis, raising the possibility of a sharp onset as plasma parameters evolve. 20 refs., 31 figs.

International Nuclear Information System (INIS)

The Level 1 probabilistic safety assessment (PSA) for Wolsong(WS) 2/3/4 nuclear power plant(NPPs) in design stage is performed using the methodologies being equivalent to PWR PSA. Accident sequence evaluation program (ASEF) human reliability analysis (HRA) procedure and technique for human error rate prediction (THERP) are used in HRA of WS 2/3/4 NPPs PSA. The purpose of this paper is to introduce the procedure and methodology of HRA in WS 2/3/4 NPPs PSA. Also, this paper describes the interim results of importance analysis for human actions modeled in WS 2/3/4 PSA and the findings and recommendations of administrative control of secondary control area from the view of human factors.

British Library Electronic Table of Contents (United Kingdom)

Intrinsic spherical aberrations of electron lenses have been the major resolution limiting factor in electron microscopes for several decades. While effective correctors have recently been implemented, an alternative to correct these aberrations is to circumvent them by scaling down lens dimensions by several orders of magnitude. We have fabricated electrostatic lenses exhibiting one micrometer diameter apertures and evaluated their beam forming properties against predictions from numerical ray tracing simulations. It turns out that it is routinely possible to shape a paraxial low-energy electron beam by such micron-sized lenses. Beam profiles have been measured both at a distant detector as well as in a plane close to the lens. It is shown that the lens can form a parallel beam extending ...

British Library Electronic Table of Contents (United Kingdom)

Temperature variations due to climate changes are a major cause of movements in a concrete structure, both in the longitudinal and transversal directions and between different parts of the structure. If these movements are restrained, stresses will be induced which may contribute to cracking. The movements are caused by complex interactions of several factors such as solar radiation, air temperature, long-wave heat radiation and wind speed. To predict the varying thermal conditions in a concrete structure a finite element model has been used. A validation of the model has been performed using field measurements in a concrete slab together with climate data from the Swedish Meteorological and Hydrological Institute to be able to use the model for simulations over long time periods and for s...

Energy Technology Data Exchange (ETDEWEB)

Ecosystems worldwide are experiencing unprecedented nitrogen enrichment through fertilization and pollution. While longterm ecological consequences are difficult to predict, it seems that plants and animals adapted to nitrogen-limited environments are at particular risk from these changes. This report summarizes the limited body of literature which addresses this important topic. From a herbivoreAes perspective, fertilization increases the nutritional quality of host plant tissues. In some cases fertilization has lead to decreased production of defensive compounds. How this affects populations of insects is unclear because fertilization affects not only herbivores but their natural enemies. This report outlines how fertilization affects tree processes such as growth, photosynthesis, and production of defensive compounds. The many factors that affect insect repsonse to fertilization and the difficulties in assessing how fertilization affects ...

British Library Electronic Table of Contents (United Kingdom)

We investigated the magnet field dependence of the X-ray pulse height and the critical current of a Ti/Au bilayer TES micro-calorimeter. The pulse height was strongly affected by the magnetic field intensity applied perpendicularly to the TES surface. We found that the critical current at zero temperature, I c0, decreased by a factor of two by applying a magnet field of ?10??T. Our data are consistent with a TES sensitivity proportional to (I/I c0)?2/3, as predicted by the Ginzburg-Landau theory. This fact implies that the shape of the R?T curve of the TES is partly determined by the critical current of the superconductor. In order to make our TES microcalorimeters less sensitive to the external magnetic field, we fabricated devices equipped with on-chip magnetic shielding. One device has ...

British Library Electronic Table of Contents (United Kingdom)

Abstract Routinely used prognostic factors fail to predict clinical outcome in a significant proportion of breast cancer patients, implying that they can not detect some important biological characteristics. Chromosomal changes have been described in breast carcinomas for many years but their significance is not clear. We compared chromosomal changes with clinico-pathological characteristics and clinical outcome in 203 breast cancer patients with a follow-up of 9-18 years. Combining data from classical cytogenetics and flow cytometry revealed chromosomal abnormalities in 142 cases (70%). Of these, 51 (35.9%) contained two or more cytogenetically abnormal clones. Polyclonality was significantly associated with poor breast-cancer-specific survival (P = 0.03) within 5 years, independent of tu...

CERN Document Server

A possibility of geophysical measurements using the large scale laser interferometrical gravitational wave antenna is discussed. An interferometer with suspended mirrors can be used as a gradiometer measuring variations of an angle between gravity force vectors acting on the spatially separated suspensions. We analyze restrictions imposed by the atmospheric noises on feasibility of such measurements. Two models of the atmosphere are invoked: a quiet atmosphere with a hydrostatic coupling of pressure and density and a dynamic model of moving region of the density anomaly (cyclone). Both models lead to similar conclusions up to numerical factors. Besides the hydrostatic approximation, we use a model of turbulent atmosphere with the pressure fluctuation spectrum f^{-7/3} to explore the Newtonian noise in a higher frequency domain (up to 10 Hz) predicting the gravitational noise background for modern gravitational wave detectors. Our estimates show ...

British Library Electronic Table of Contents (United Kingdom)

Orientation in the environment can draw on a variety of cognitive strategies. We asked 634 healthy volunteers to perform a comprehensive battery administered through an internet website (www.gettinglost.ca), testing different orientation strategies in virtual environments to determine the effect of age and gender upon these skills. Older participants (46-67years of age) performed worse than younger participants (18-30 or 31-45years of age) in all orientation skills assessed, including landmark recognition, integration of body-centered information, forming association between landmarks and body turns, and the formation and use of a cognitive map. Among all tests, however, the ability to form cognitive maps resulted to be the significant factor best at predicting the individuals' age group. ...

Energy Technology Data Exchange (ETDEWEB)

This paper discusses a database of information collected and organized during the past eight years from 2,000 producing oil wells in the United States, all of which have been treated with special applications techniques developed to improve the effectiveness of MEOR technology. The database, believed to be the first of its kind, has been generated for the purpose of statistically evaluating the effectiveness and economics of the MEOR process in a wide variety of oil reservoir environments, and is a tool that can be used to improve the predictability of treatment response. The information in the database has also been evaluated to determine which, if any, reservoir characteristics are dominant factors in determining the applicability of MEOR.

CERN Document Server

The adjoint of an ocean general circulation model is used as a tool for investigating the causes of changes in ENSO SST indices. We identify adjoint Kelvin and Rossby waves in the sensitivities to sea level and wind stress at earlier times, which can be traced back for more than a year through western and weak eastern boundary reflections. Depending on the thermocline depth the first and second baroclinic modes are excited. The sensitivities to the heat flux and SST are local and decay in about a month. The sensitivities to the fluxes are converted into the influence of SST using the adjoint of a statistical atmosphere model. Focusing on SST perturbations in the index region itself, we recover, up to a scale factor, the delayed oscillator concept.

British Library Electronic Table of Contents (United Kingdom)

Purpose To evaluate disease failure patterns and overall survival (OS) of women with triple-negative (TN) breast cancer who underwent breast-conserving therapy (BCT) and to understand the relationship of TN tumors with other prognostic factors. Patients and Methods The Surveillance, Epidemiology, and End Results (SEER) registry identified 562 women diagnosed and/or treated with unilateral invasive breast cancer during 2003?2004 at three Emory hospitals. After medical record review, 193 eligible women, with all tumor types, received BCT. Primary endpoints (local, regional, and distant recurrences) and secondary endpoint (OS) were evaluated using chi-square tests and Cox proportional hazards models. Results Of the 193 women, 33 (17.1%) had TN tumors and 160 (82.9%) had non-TN tumors. Patient...

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A real-time orbit feedback system has been implemented at the Advanced Photon Source in order to meet the stringent orbit stability requirements. The system reduces global orbit motion below 30Hz by a factor of four to below 5{micro}m rms horizontally and 2{micro}m rms vertically. This paper focuses on dynamic orbit stability and describes the all-digital orbit feedback system that has been implemented at the APS. Implementation of the global orbit feedback system is described and its latest performance is presented. Ultimately, the system will provide local feedback at each x-ray source point using installed photon BPMs to measure x-ray beam position and angle directly. Technical challenges associated with local feedback and with dynamics of the associated corrector magnets are described. The unique diagnostic capabilities provided by the APS system are discussed with reference to their use in identifying sources of the underlying orbit ...

Energy Technology Data Exchange (ETDEWEB)

A stable power system stabilizer (PSS) based on the inverse dynamics of the controlled system using an artificial neural network (ANN) is suggested to enhance the dynamic performances of a power system. First, an output feedback control law is driven with some conditions satisfied, which guarantees the internal stability and robustness against the asymptotically stable external disturbances. Then the control law is implemented using the inverse dynamics of the controlled plant. The inverse dynamics of the controlled plant is identified by an ANN, inverse dynamics neural network (IDNN), off-line. The pole-shifting technique and a scaling factor are introduced for the control system to meet the conditions for internal stability and robustness. The proposed controller is applied to a typical single-machine infinite-bus power system. Simulation results under various operation conditions are given which show that the proposed controller damps the ...

Energy Technology Data Exchange (ETDEWEB)

The AdS/CFT correspondence is a powerful tool to study the properties of conformal QCD at strong coupling in terms of a higher dimensional dual gravity theory. The power-law falloff of scattering amplitudes in the non-perturbative regime and calculable hadron spectra follow from holographic models dual to QCD with conformal behavior at short distances and confinement at large distances. String modes and fluctuations about the AdS background are identified with QCD degrees of freedom and orbital excitations at the AdS boundary limit. A description of form factors in space and time-like regions and the behavior of light-front wave functions can also be understood in terms of a dual gravity description in the interior of AdS.

British Library Electronic Table of Contents (United Kingdom)

BackgroundPeritoneal metastasis occurs in up to 30% of patients with gastric cancer. The aim of this experimental study is to develop and validate a novel ex vivo model of the human peritoneum to better identify factors involved in the development of peritoneal metastasis in order to improve its management and prognosis. MethodsPeritoneal discs harvested from hernia sacs obtained at inguinal hernia surgery were suspended in media using Teflon rings. Viability of the tissue was investigated using MTS assay, light and scanning electron microscopy (LM and SEM) over 72 h. To assess validity of the model, phenotypic changes in tumor cells were investigated. Changes in matrix metalloproteinases (MMP)-2 and -9 activities in HGC and AGS gastric adenocarcinoma cells after co-culture were investigat...

British Library Electronic Table of Contents (United Kingdom)

Objective:- To review the rate of inadvertent cystotomy during laparoscopic hysterectomy performed by the Sydney West Advanced Pelvic Surgery Unit (SWAPS). To compare this rate with other published data. To identify the risk factors for bladder injury at laparoscopic hysterectomy and to review the management and outcome following such injury. Method:- This was a retrospective observational study. All hysterectomies where the SWAPS clinical fellow was involved were included. The study period was from January 2001 to June 2009. Simple statistical formulae were used to analyse data in this study. Results:- There were 1223 hysterectomies performed during this period. Eighty-one percent of these were performed laparoscopically. There were 14 (1.1%) bladder injuries reported during this period. ...

British Library Electronic Table of Contents (United Kingdom)

Histone deacetylase (HDAC) inhibitors have been actively exploited as potential anticancer agents. To identify gene targets of HDAC inhibitors, we found that HDAC inhibitors such as sodium butyrate, scriptaid, apicidin and oxamflatin induced the expression of 15-hydroxyprostaglandin dehydrogenase (15-PGDH), a potential cyclooxygenase-2 (COX-2) antagonist and tumor suppressor, in a time and concentration dependent manner in A549 and H1435 lung adenocarcinoma cells. Detailed analyses indicated that HDAC inhibitors activated the 15-PGDH promoter-luciferase reporter construct in transfected A549 cells. A representative HDAC inhibitor, scriptaid, and its negative structural analog control, nullscript, were further evaluated at the chromatin level. Scriptaid but not nullscript induced a signific...

British Library Electronic Table of Contents (United Kingdom)

Reasons for variation in transfusion practice in orthopedic surgery are not well understood. This systematic review identified and appraised the quality of the literature in this area to assess the impact of factors associated with the use of allogeneic red blood cell (RBC) transfusion in orthopedic procedures. MEDLINE and EMBASE databases were searched for relevant English language publications. Articles containing a range of MeSH and text terms regarding ''blood transfusion,'' ''predictors,'' and ''multiple logistic regression'' were retrieved. Articles that focused on patients undergoing orthopedic procedures and that met prespecified inclusion criteria were appraised in terms of potential bias and the appropriateness of statistical approach. A total of 3641 citations were retrieved, an...

British Library Electronic Table of Contents (United Kingdom)

In this investigation, a forward osmosis (FO) dewatering process is evaluated as an alternative for dewatering orange peel press liquor. The press liquor is concentrated by removing water via osmosis into a concentrated ''draw solution'' across a polymeric cellulose acetate membrane. For this investigation, the draw solution consisted of sodium chloride at two different concentrations (2M and 4M). These draw solutions were used to concentrate synthetic press liquor. Concentration factors up to 3.7 resulted when using a 4M NaCl draw solution and the synthetic press liquor. Also during this investigation, fouling behavior was observed and the mechanisms of fouling elucidated through a systematic approach. This approach identified the key components of the press liquor that were primarily res...

Energy Technology Data Exchange (ETDEWEB)

The analysis is submitted in support of the effluent limitations guidelines and standards for the Coastal Oil and Gas Industry. The report analyzes the cost-effectiveness of 10 regulatory options organized by three wastestreams. The document compares the total annualized cost incurred for each of the regulatory options within each wastestream to the corresponding effectiveness of that option in reducing the discharge of pollutants. Section Two discusses the cost-effectiveness methodology used and identifies the pollutants included in the analysis, presenting their toxic weighting factors and removal efficiencies. Section Three presents the results of the analysis. In Section Four, the cost-effectiveness values are compared to cost-effectiveness values for other promulgated rules. Appendix A presents data on pollutants, pollutant removals, annualized costs, and other, more detailed information.

British Library Electronic Table of Contents (United Kingdom)

Mammary glands are special tissue characterized by proliferation of the epithelium, during puberty and pregnancy and by programmed cell death, during involution. In this study, apoptosis was identified by TUNEL staining and then related to cell proliferation, as determined by Ki-67 staining. The apoptotic index was at its highest at 8 days of involution, whereas the proliferation index was at its highest during lactation. Caspase-3 was immunolocalised only in mast cells and along the basal membrane in the mammary tissue at -10 days from lambing, 150 days of lactation and at 8 days of involution. This finding could indicate that caspase-3 is not involved in sheep mammary gland apoptosis, but that other proteins - such as apoptosis inducing factor (AIF) - can trigger apoptosis, through the m...

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The effects of reservoir layering and gravity segregation on nonisothermal injection and falloff tests are investigated. Results show that layering does not affect injection or falloff data if all the layers are permeable and accept fluids from the wellbore. In such cases, the average permeability, skin factor, and distance to the thermal front can be calculated using the techniques developed for homogeneous reservoirs. Special considerations have to be taken for cases where several layers are impermeable or are permeable but do not accept fluids of the well face. In the first case (impermeable layers), knowledge of the total thickness of the permeable layers is required for the existing techniques to be applied successfully. In the second case, the existing techniques cannot be applied, but characteristic responses from injection and falloff test are seen; therefore, this case can be identified easily. 13 refs., 8 figs.

Science.gov (United States)

A new algorithm for the design of decentralized output feedback stabilizers for large-scale electric power systems is presented in this paper. In the proposed approach, the generators which are most effective for stabilizer applications are first identified by using participation factors. Then an efficient algorithm based on decentralized pole assignment is proposed for the determination of the parameters of the power system stabilizers which, due to the difficulty associated with the communication among the geographically dispersed generating stations in a large power system, are essentially decentralized compensators using local generator outputs as their feedback signals. The proposed method is computationally efficient and can be applied to any large-scale system. The simplicity and effectiveness of the proposed method are demonstrated by an example of stabilizer design for a practical power system.

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It is necessary to identify those measurable soil parameters which dictate the severity of the corrosion problem for coated irons and steels. When this is done, meaningful accelerated aging tests can be designed to validate the reduced corrosion rate for the planned coating. The following discussion introduces the important concepts and measurement parameters in the (a) design of accelerated aging tests, and (b) evaluation of the planned installation site for corrosion potential. Certain combinations of soil oxidation reduction potential (ORP) or electric potential (Eh), acidity (pH), fertilizer, water table, and soil hydraulic conductivity can result in severe corrosion of buried steel/iron vessels. If there are power lines nearby, additional loss of vessel material to the soil will occur. These factors are discussed.

British Library Electronic Table of Contents (United Kingdom)

BACKGROUND: Glyphosate resistance has been confirmed in 58 populations of Lolium rigidum (Gaud.), a major weed of crops in southern Australia. Extensive use of glyphosate in conjunction with minimal soil disturbance has been identified as high risk for resistance to that herbicide. Land managers need a simple method for rapid assessment of the risk of resistance occurring as a result of past and proposed future management practices. Modelled on risk assessment nomographs, a simple calculator for indicating the risk of evolved glyphosate resistance in L. rigidum is described.RESULTS: The calculator uses the generations since first use and the frequency of use of glyphosate in combination with historical cultivation levels as critical factors for determining the risk of glyphosate resistance...

International Nuclear Information System (INIS)

The RADionuclide Transport, Removal, And Dose (RAD-TRAD) code is designed for U.S. Nuclear Regulatory Commission (USNRC) use to calculate the radiological consequences to the off-site population and to control room operators following a design-basis accident at light water reactor (LWR) power plants. This code utilizes updated reactor accident source terms published in draft NUREG-1465. The code will track the transport of radionuclides as they are released from the reactor pressure vessel, travel through the primary containment and other buildings, and are released to the environment. As the radioactive material is transported through the primary containment and other buildings, credit for several removal mechanisms may be taken, including sprays, suppression pools, overlying pools, filters, and natural deposition. Simple models are available for these different removal mechanisms that use, as input, information about the conditions in the plant and predict either ...

CERN Document Server

We present a fully relativistic formalism for describing neutrino-induced $\\Delta$-mediated single-pion production from nuclei. We assess the ambiguities stemming from the $\\Delta$ interactions. Variations in the cross sections of over 10% are observed, depending on whether or not magnetic-dipole dominance is assumed to extract the vector form factors. These uncertainties have a direct impact on the accuracy with which the axial-vector form factors can be extracted. Different predictions for $C_5^A(Q^2)$ induce up to 40-50% effects on the $\\Delta$-production cross sections. To describe the nucleus, we turn to a relativistic plane-wave impulse approximation (RPWIA) using realistic bound-state wave functions derived in the Hartree approximation to the $\\sigma$-$\\omega$ Walecka model. For neutrino energies larger than 1 GeV, we show that a relativistic Fermi-gas model with appropriate binding-energy correction produces ...

International Nuclear Information System (INIS)

The studies of forced jet augmentation of natural convection heat transfer are introduced. It investigates experimentally mixed convection and heat transfer augmentation by forced jets in a large rectangular enclosure with a vertical cooling surface. The experiment is designed to measure the key parameters governing the heat transfer augmentation by a forced jet, and to investigate the effects of geometric factors, including the jet diameter, jet injection orientation, interior structures, and enclosure aspect ratio, on conditions simulating those of actual passive containment cooling systems and scales approaching those of actual containment buildings or compartments. The tests that cover a variety of injection modes will contribute to reveal the nature of mixing and stratification phenomena under accident conditions to a new generation of inherently safe reactors. With similarity considerations on governing equations, the heat transfer of mixed convection can be ...

International Nuclear Information System (INIS)

DF (decontamination factor) of two types of air filter was investigated against "1"9"8Au aerosol particles with AMAD (activity median aerodynamic diameter) = 1.2 #mu#m and #sigma#g (geometric standard deviation) = 2.0. One of the filters, SO filter, is HEPA (high efficiency particulate air) filter media with 46 mm#phi#, and the other is HE-40T (cellulose-glass fiber filter for dust sampling) filter media with 40 mm#phi#. DF of the SO filter was found to be over 5 x 10"4 at air flow rate of 1 l/min. And DF of HE-40 T filter was determined to be 94#+-#4 at the same airflow rate. In the multistage HE-40 T filter system, DF decreased at each succeeding stage. It was confirmed by numerical simulation that the decrease of DF was not inconsistent with the decrease of collection performance in each successive filter. It was also confirmed that DF could be predicted by the numerical simulaiton, if particle penetration function of filter and size ...

Energy Technology Data Exchange (ETDEWEB)

This document is the final report for Cooperative Agreement DE-FC26-04NT42314, 'Kinetics Study of Mercury Reactions in FGD Liquors'. The project was co-funded by the U.S. DOE National Energy Technology Laboratory and EPRI. The objective of the project has been to determine the mechanisms and kinetics of the aqueous reactions of mercury absorbed by wet flue gas desulfurization (FGD) systems, and develop a kinetics model to predict mercury reactions in wet FGD systems. The model may be used to determine optimum wet FGD design and operating conditions to maximize mercury capture in wet FGD systems. Initially, a series of bench-top, liquid-phase reactor tests were conducted and mercury species concentrations were measured by UV/visible light spectroscopy to determine reactant and byproduct concentrations over time. Other measurement methods, such as atomic absorption, were used to measure concentrations of vapor-phase elemental mercury, that cannot be ...

Energy Technology Data Exchange (ETDEWEB)

Mechanistic models of aerosol decontamination by an overlying water pool during core debris/concrete interactions and spray removal of aerosols from a Mark I drywell atmosphere are developed. Eighteen uncertain features of the pool decontamination model and 19 uncertain features of the model for the rate coefficient of spray removal of aerosols are identified. Ranges for values of parameters that characterize these uncertain features of the models are established. Probability density functions for values within these ranges are assigned according to a set of rules. A Monte Carlo uncertainty analysis of the decontamination factor produced by water pools 30 and 50 cm deep and subcooled 0--70 K is performed. An uncertainty analysis for the rate constant of spray removal of aerosols is done for water fluxes of 0.25, 0.01, and 0.001 cm{sup 3} H{sub 2}O/cm{sup 2}-s and decontamination factors of 1.1, 2, 3.3, 10, 100, and 1000.

Energy Technology Data Exchange (ETDEWEB)

This study reviews past assessments of world oil, natural gas, and oil-shale resources. It identifies the methods used in making these assessments (historical statistics, geological analogy, engineering, and probabilistic), the geographical coverage, the time horizons, and the major assumptions about such factors as discovery rates, and recovery factor. The period covered extends from the end of World War II to the end of 1980. Conclusions are presented on the current state of knowledge and understanding concerning each of these three hydrocarbon resources. Regarding world oil resources, an assumed consensus on 2000 billion barrels ultimately recoverable is, in fact, only weakly supported. Close examination of its component parts reveals widespread disagreement. World natural gas resources are even less well understood. And it is premature to venture a meaningful assessment of world oil-shale resources. Thus, our knowledge ...

Science.gov (United States)

Endoreduplication represents a cell cycle variant during which multiple rounds of DNA replication occur without subsequent chromosome separation and cytokinesis, resulting into a cellular increase of the DNA content. Although the DNA ploidy level of cells is controlled by external stimuli such as light, currently limited knowledge is available on how environmental signals regulate the endoreduplication cycle at the molecular level. Previously, we have demonstrated that the conversion from the mitotic cell cycle into an endoreduplication cycle is mediated by the atypical E2F transcription factor DEL1 that operates as a repressor of endocycle onset. Here, we identified DEL1 as a transcriptional target of the classical E2Fb and E2Fc transcription factors that antagonistically control DEL1 transcript levels through competition for a single E2F cis-acting binding site. Correspondingly with the reported opposite effect of light ...

Science.gov (United States)

The Drosophila melanogaster tissue-specific transcription factor NTF-1 was originally identified in vitro as a protein that could bind to and activate transcription from the Dopa decarboxylase (Ddc) gene. A structure-function analysis of NTF-1 led to the identification of a discrete amino-terminal activation domain. Here, we report that an NTF-1 mutant lacking the activation domain acts as a trans-dominant inhibitor of NTF-1 activation in tissue culture cells by forming inactive heterodimers with the full-length protein. Ectopically expressing this dominant-negative protein or the full-length protein in developing Drosophila embryos leads to dire developmental consequences. Overexpressing the trans-dominant NTF-1 leads to lethality, while overexpressing full-length NTF-1 results in both lethality and morphogenetic defects. Our results suggest that both the activity and the regulation of NTF-1 are critical for viability and proper development of ...

Energy Technology Data Exchange (ETDEWEB)

The US Environmental Protection Agency (EPA) conducted a cost-effectiveness (CE) analysis to estimate the incremental cost of complying with the proposed effluent limitation guidelines (ELGs) for the coastal oil and gas industry (EPA 1995a). EPA`s CE analysis calculates the pounds of each pollutant that would be removed if the chosen discharge option is selected. In 1993, EPA issued final ELGs for the offshore oil and gas industry and published an offshore CE analysis. The chemical characteristics of produced water from the offshore region are essentially the same as those of produced water from the coastal region. It was surprising, therefore, that EPA chose a much longer list of pollutants and generally stricter weighting factors for the coastal CE analysis. This report reviews the data, assumptions, and analyses used in EPA`s coastal CE analysis and identifies alternate data, assumptions, and analyses that could lead to significantly ...

Science.gov (United States)

As part of the Wisconsin road weather safety initiative, the objective of this study is to assess the effects of rainfall on the severity of single-vehicle crashes on Wisconsin interstate highways utilizing polychotomous response models. Weather-related factors considered in this study include estimated rainfall intensity for 15 min prior to a crash occurrence, water film depth, temperature, wind speed/direction, stopping sight distance and deficiency of car-following distance at the crash moment. For locations with unknown weather information, data were interpolated using the inverse squared distance method. Non-weather factors such as road geometrics, traffic conditions, collision types, vehicle types, and driver and temporal attributes were also considered. Two types of polychotomous response models were compared: ordinal logistic and sequential logistic regressions. The sequential logistic regression was tested with forward and backward ...

International Nuclear Information System (INIS)

Epidermal growth factor receptor (EGFR) gene alterations have been found in human lung cancers. However, there is no information on the factors inducing EGFR mutations. In rodents, K-ras mutations are frequently found in many lung carcinogenesis models, but hitherto, Egfr mutations have not been reported. Their presence was therefore investigated in representative lung carcinogenesis models with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), N-nitrosobis(2-hydroxypropyl)amine (BHP), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MelQx) and ethyl carbamate (urethane), as well as X-ray irradiation. With the chemical carcinogenesis models, no mutations were detected in Egfr, which is in clear contrast to the high rates observed in either codon 12 or 61 of K-ras (21/23 of the lung tumors induced with NNK, 4/5 with MelQx, 1/4 with urethane and 7/18 with BHP). However, in the X-ray-induced lung tumors, Egfr mutations with amino acid ...

Science.gov (United States)

Context: The Balanced Budget Act (BBA) of 1997 allowed some rural hospitals meeting certain requirements to convert to Critical Access Hospitals (CAHs) and changed their Medicare reimbursement from prospective to cost-based. Some subsequent CAH-related laws reduced restrictions and increased payments, and the number of CAHs grew rapidly. Purpose: To examine factors related to hospitals' decisions to convert and time to CAH conversion. Methods: Eighty-nine rural hospitals in Iowa were characterized and observed from 1998 to 2005. Cox proportional hazards models were used to identify the determinants of time to CAH conversion. Findings: T-test and one-covariate Cox regression indicated that, in 1998, Iowa rural hospitals with more staffed beds, discharges, and acute inpatient days, higher operating margin, lower skilled swing bed days relative to acute days, and located in relatively high density counties were more likely to convert later or not ...

Energy Technology Data Exchange (ETDEWEB)

Objective: To retrospectively evaluate the results of conservative therapy using escorpal iodine-125 (model 6711, Amershan) plaque for brachytherapy of choroidal melanoma. Materials And Methods: We evaluated 49 patients with choroidal melanoma treated at 'Hospital do Cancer', Sao Paulo, Brazil, from March 2001 to January 2003. The following clinical parameters were analyzed and correlated with local control and survival rate: gender, age, lesion dimension, treatment duration, as well as doses in apex and base of the tumors. Results: The maximum diameter and height of the base of the tumors treated were 17 mm and 12 mm, respectively. Doses at those points ranged from 213 to 463 Gy (median: 347 Gy) and 51 to 250 Gy (median: 91 Gy), respectively. The actuarial rates of ocular preservation, disease free survival and ocular preservation in 2-years were 96%, 93.5% and 96.3%, respectively. A tumor height < 6 mm was the only predictive ...

Energy Technology Data Exchange (ETDEWEB)

A prediction of delayed neutron yields for actinides which are important in the nuclear energy field is given. The prediction is based on a correlation related to a suggested cluster structure of the nucleus. (author).

Energy Technology Data Exchange (ETDEWEB)

This progress report consists of an article, the abstract of which follows, and apparently the references and vita from a proposal. A review of perturbation diagnostics applied to microwave resonant cavity discharges is presented. The classical microwave perturbation technique examines the shift in the resonant frequency and cavity quality factor of the resonant cavity caused by low electron density discharges. However, modifications presented here allow the analysis to be applied to discharges with electron densities beyond the limit predicted by perturbation theory. An {open_quote}exact{close_quote} perturbation analysis is presented which models the discharge as a separate dielectric, thereby removing the restrictions on electron density imposed by the classical technique. The {open_quote}exact{close_quote} method also uses measurements of the shifts in the resonant conditions of the cavity. Thirdly, an electromagnetic analysis is presented ...