WorldWideScience
1

Echocardiographic assessment and percutaneous closure of multiple atrial septal defects  

UK PubMed Central (United Kingdom)

Atrial septal defect closure is now routinely performed using a percutaneous approach under echocardiographic guidance. Centrally located, secundum defects are ideal for device closure but there is...Full Text Available

3

Correlation between N-Terminal Pro-Brain Natriuretic Peptide and Doppler Echocardiographic Parameters of Left Ventricular Filling Pressure in Atrial Fibrillation  

UK PubMed Central (United Kingdom)

BackgroundAtrial fibrillation (AF) is the most common cardiac arrhythmia with a population prevalence of about 1%. Natriuretic peptide level is elevated in patients with AF with...Full Text Available

2011-03-01

4

Accuracy of electrocardiographic and echocardiographic indices in predicting life threatening ventricular arrhythmias in patients operated for tetralogy of Fallot  

UK PubMed Central (United Kingdom)

OBJECTIVE—To validate the accuracy of the prognostic significance of non-invasive clinical diagnostic indices as predictors of sustained ventricular tachycardia (sVT) or fibrillation...Full Text Available

1999-06-01

5

How Do Police Respond to Stalking? An Examination of the Risk Management Strategies and Tactics Used in a Specialized Anti-Stalking Law Enforcement Unit  

British Library Electronic Table of Contents (United Kingdom)

How do police respond to and manage complaints of stalking? To answer this question, we conducted a 3-phase study. First, we reviewed the literature to identify risk management tactics used to combat stalking. Second, we asked a group of police officers to review those tactics for completeness and group them into categories reflecting more general risk management strategies. The result was 22 categories of strategies. Finally, we used qualitative methods to evaluate the files of 32 cases referred to the specialized anti-stalking unit of a metropolitan police department. We coded specific risk management tactics and strategies used by police. Results indicated that a median number of 19 specific tactics from 7 general strategies were used to manage risk. Also, the implementation of strategi...

2011-01-01

6

Reconceptualizing the Native/Nonnative Speaker Dichotomy  

British Library Electronic Table of Contents (United Kingdom)

This study reconceptualizes the native/nonnative dichotomy and provides a powerful lens to examine linguistic identities. In a study of 25 linguistically diverse teacher candidates in Canada, the respondents' native and nonnative self-ascription and self-assessed level of proficiency was juxtaposed with the judgment of their instructors. This process revealed that the native/nonnative dichotomy falls short in capturing the multifaceted nature of individuals' diverse linguistic identities and tends to misrepresent them. Within the specific social context under investigation, 6 linguistic categories that better represented the true linguistic identity of participants were identified. This inquiry reconceptualizes the controversial native/nonnative dichotomy by suggesting that linguistic iden...

2011-01-01

7

Adaptive System and Method for Responding to Computer ...  

Science.gov (United States)

Page 1. Adaptive system and method for responding to computer network security attacks Abstract A dynamic network security ...

2002-07-11

8

Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection.  

Science.gov (United States)

African bovine trypanosomiasis caused by Trypanosoma sp., is a major constraint on cattle productivity in sub-Saharan Africa. Some African Bos taurus breeds are highly tolerant of infection, but the potentially more productive Bos indicus zebu breeds are much more susceptible. Zebu cattle are well adapted for plowing and haulage, and increasing their tolerance of trypanosomiasis could have a major impact on crop cultivation as well as dairy and beef production. We used three strategies to obtain short lists of candidate genes within QTL that were previously shown to regulate response to infection. We analyzed the transcriptomes of trypanotolerant N'Dama and susceptible Boran cattle after infection with Trypanosoma congolense. We sequenced EST libraries from these two breeds to identify polymorphisms that might underlie previously identified quantitative trait loci (QTL), and we assessed QTL regions and candidate loci for evidence of selective ...

2011-05-18

9

Assessing aortic valve area in aortic stenosis by continuity equation: a novel approach using real-time three-dimensional echocardiography  

UK PubMed Central (United Kingdom)

AimsTwo-dimensional echocardiographic (2DE) continuity-equation derived aortic valve area (AVA) in aortic stenosis (AS) relies on non-simultaneous measurement of left ventricular...Full Text Available

2008-10-01

10

Clustering with Prototype Extraction for Census Data Analysis  

CERN Document Server

Not long ago primary census data became available to publicity. It opened qualitatively new perspectives not only for researchers in demography and sociology, but also for those people, who somehow face processes occurring in society. In this paper authors propose using Data Mining methods for searching hidden patterns in census data. A novel clustering-based technique is described as well. It allows determining factors which influence people behavior, in particular decision-making process (as an example, a decision whether to have a baby or not). Proposed technique is based on clustering a set of respondents, for whom a certain event have already happened (for instance, a baby was born), and discovering clusters' prototypes from a set of respondents, for whom this event hasn't occurred yet. By means of analyzing clusters' and their prototypes' characteristics it is possible to identify which factors influence the ...

2011-01-01

11

Finite element analysis of a scanning x-ray microscope micropositioning stage  

Energy Technology Data Exchange (ETDEWEB)

A micropositioning stage for use with an x-ray microscope has been developed to scan samples over a 100 {mu}m{times}100-{mu}m area with a resolution of 100 A. The stage employs flexure hinges driven by piezoelectric actuators to achieve this high positioning accuracy. Due to the severe geometry of the hinges, stresses and deflections are determined (via finite element methods) to ensure a credible design. Since the stage is to be used in a stepping capacity, natural frequencies are computed to identify resonant conditions which could potentially cause excessive deflections. The finite element models show that the stage responds like a discrete lumped-mass system for the lower modes, and a continuous system with flexural characteristics for the higher modes.

1992-01-01

12

Vigdor et al. respond  

Energy Technology Data Exchange (ETDEWEB)

Possible explanations are given for the observed asymmetry of the analyzing power in several (rho,..pi../sup -/) reactions.

1985-03-18

13

Monitoring the effect of chemotherapy in Ewing's sarcoma of bone with MR imaging  

International Nuclear Information System (INIS)

Magnetic resonance (MR) imaging was performed in 26 patients with Ewing's sarcoma of bone preceding and following neoadjuvant chemotherapy, to assess tumour response non-invasively prior to surgery. T1- and T2-weighted spin echo images were obtained. Changes including intra- and extramedullary signal intensities, tumour demarcation, tumour volume and the appearance of residual extramedullary tumour were compared with histophathology of the resected specimens. Reduction of tumour volume was significantly higher in good responders. Other single parameters did not correlated with histologic tumour response. However, when several MR parameters summarized in a classification system were combined, a positive correlation with histopathologic response was found. A limited decrease of tumour volume (<25 %) and/or residual soft tissue mass following chemotherapy correlated with a poor response. An inhomogeneous, well-defined cuff of abnormal tissue encircling the bone ...

14

ExternE - valuation of hydro power in Klippen. Final report; ExternE - vaerdering av vattenkraft i Klippen. Slutrapport  

Energy Technology Data Exchange (ETDEWEB)

ExternE is a pan{sub E}uropean project aimed at identifying and quantifying external effects from different energy production technologies around Europe. The Swedish implementation carried out case studies on a biomass plant, a coal plant and a hydro power plant. The conventional approach within the ExternE project is to estimate impacts for each priority pathway associated with the fuel cycle, and then economic methods to obtain estimates for the economic damage of each particular impact pathway. However, in the case of hydro power, it is generally not possible to estimate the most important impacts quantitatively. Therefore, a contingent valuation (CV) study was initiated. In a typical CV-study, a selection of individuals are asked to state their willingness to pay for a certain environmental improvement or to avoid an environmental damage. Welfare economic theory suggests that the well-being effects on people from a change from one situation to another can be ...

1998-08-01

15

The energy bank: Opening the door to the competitive market  

Energy Technology Data Exchange (ETDEWEB)

The UNITIL Companies have identified the need to undertake new economic development initiatives and to respond to an increasingly competitive energy marketplace. The economy of UNITIL`s service areas and New England generally have suffered from the perception that energy prices, and electricity prices in particular, are very high and non-competitive. However, opportunities now exist for more competitive priced electricity services to be made available to meet the needs of economic development. The introduction of Energy Bank{trademark} was designed to meet this objective through a competitively priced, market-based option for new or expanding industrial loads. The Energy Bank{trademark} is priced at about 5 cents/kWh, a rate 40% below the regional average industrial rate. As Energy Bank{trademark} grows, it will yield substantial benefits to all customers in UNITIL`s service areas, through increased local economic activity, reduced power costs ...

1996-03-01

16

Methods for preventing steam generator failure or degradation  

Energy Technology Data Exchange (ETDEWEB)

PWR steam generators have suffered from a variety of degradation phenomena. This paper identifies the corrosion-related defects and their probable causes and suggests approaches to correct and prevent corrosive activity. In the attempt to solve the degradation problems, research programs have concentrated on modifying materials, stresses, and the chemical environment in both new and operating steam generators. The following corrosion-related defects have been studied: tube wastage, denting, primary side (ID) intergranular stress corrosion cracking (IGSCC), OD-initiated intergranular attack (IGA), pitting, and corrosion fatigue. Plants affected by wastage have greatly reduced their problem by adopting an all volatile treatment (AVT). In the case of denting, a less aggressive chemical environment is recommended. Primary side IGSCC responds to temperature reduction, stress relief, and material improvements, while flushing and boric acid addition ...

1986-01-01

17

Methods for preventing steam generator failure or degradation  

International Nuclear Information System (INIS)

PWR steam generators have suffered from a variety of degradation phenomena. This paper identifies the corrosion-related defects and their probable causes and suggests approaches to correct and prevent corrosive activity. In the attempt to solve the degradation problems, research programs have concentrated on modifying materials, stresses, and the chemical environment in both new and operating steam generators. The following corrosion-related defects have been studied: tube wastage, denting, primary side (ID) intergranular stress corrosion cracking (IGSCC), OD-initiated intergranular attack (IGA), pitting, and corrosion fatigue. Plants affected by wastage have greatly reduced their problem by adopting an all volatile treatment (AVT). In the case of denting, a less aggressive chemical environment is recommended. Primary side IGSCC responds to temperature reduction, stress relief, and material improvements, while flushing and boric acid addition ...

18

Mechanical Engineering and Design of the LHC Phase II Collimators  

CERN Document Server

Phase II collimators will complement the existing system to improve the expected high RF impedance and limited efficiency of Phase I jaws. An international collaborative effort has been launched to identify novel advanced materials responding to the very challenging requirements of the new collimators. Complex numerical calculations simulating extreme conditions and experimental tests are in progress. In parallel, an innovative modular design concept of the jaw assembly is being developed to allow fitting in alternative materials, minimizing the thermally induced deformations, withstanding accidents and accepting high radiation doses. Phase II jaw assembly is made up of a molybdenum back-stiffener ensuring high geometrical stability and a modular jaw split in threes sectors. Each sector is equipped with a high-efficiency independent cooling circuit. Beam position monitors (BPM) are embedded in the jaws to fasten setup time and improve beam ...

2010-01-01

19

Conforth Ranch Wildlife Mitigation Feasibility Study, McNary, Oregon : Annual Report.  

Energy Technology Data Exchange (ETDEWEB)

The 2,860-acre Conforth Ranch near Umatilla, Oregon is being considered for acquisition and management to partially mitigate wildlife losses associated with McNary Hydroelectric Project. The Habitat Evaluation Procedures (HEP) estimated that management for wildlife would result in habitat unit gains of 519 for meadowlark, 420 for quail, 431 for mallard, 466 for Canada goose, 405 for mink, 49 for downy woodpecker, 172 for yellow warbler, and 34 for spotted sandpiper. This amounts to a total combined gain of 2,495 habitat units -- a 110 percent increase over the existing values for these species combined of 2,274 habitat units. Current water delivery costs, estimated at $50,000 per year, are expected to increase to $125,000 per year. A survey of local interest indicated a majority of respondents favored the concept with a minority opposed. No contaminants that would preclude the Fish and Wildlife Service from agreeing to accept the property were ...

1991-03-01

20

Chromosomal localization of the human retinoid X receptors  

Energy Technology Data Exchange (ETDEWEB)

The recently described retinoid X receptors (RXRs) respond to the novel retinoid 9-cis-retinoic acid and also serve as heterodimeric partners for the vitamin D, thyroid hormone, and retinoic acid receptors (VDR, TR, and RAR, respectively). In this work, the authors report high-resolution localization of the human RXR genes within cytogenetic bands and also within a standard reference map of cosmid DNA markers on human chromosomes. They have determined the location of the human RXR genes by pairwise hybridization of the RXR cosmids and reference markers, using fluorescence in situ hybridization. They localized (i) RXR[alpha] (RXRA) to chromosome 9 band q34.3; (ii) RXR[beta] (RXRB) to chromosome 6 band 21.3; and (iii) RXR[gamma] (RXRG) to chromosome 1 band q22-q23. Six retinoid-responsive transcription factors have been identified so far, including three retinoic acid receptors in addition to the three RXRs. Interestingly, each of these receptors ...

1994-04-01

21

Behavioral effects of exposure to the TEMPO high-power microwave system. Interim report, January-June 1987  

Energy Technology Data Exchange (ETDEWEB)

Safety standards for exposure to radiofrequency radiation must be based upon biologic consequences of exposure to such environments. Behavioral-based measures are considered to be the most-sensitive indices of biological effects. Current safety guidelines are based upon average power density and may not be relevant to the high-peak-power, short pulse width microwave radiation produced by newly developed high peak power microwave sources. The effects of exposure to high-peak-power radiation on reflexive responding and motor function in Fischer 344/N rats were assessed by measuring startle and general activity, and disruption of on-going performance of a rotarod task, respectively. The emitter used was the TEMPO repeat pulse axially extracted vircator. Exposure to single pulses resulted in significant startle responses. Exposure to 1 pps for 10 s produced significant alterations in baseline activity and marked disruption of performance of the rotarod task. The ...

1988-03-01

22

ST-segment changes after direct current external cardioversion for atrial fibrillation. Incidence, characteristics and predictive factors  

British Library Electronic Table of Contents (United Kingdom)

Background: Incidence, characteristics and predictive factors of transient ST-segment changes after DC shock are poorly known. Methods: 91 consecutive pts referred for external cardioversion of atrial fibrillation (AF) (61 men, 69+/-10yo) were prospectively included. The presence of ST elevation or depression was assessed on 12 lead-ECG immediately after the first DC shock. Correlations with DC shock characteristics (monophasic/biphasic and energy), clinical variables, echocardiographic parameters, biological parameters, medications, anesthesic drugs as well with morphological features were made. Results: 18 and 20 pts underwent 200J or 300J monophasic and 53 pts 200J biphasic DC shocks. We found an incidence of 48% for ST-segment changes: 35% for ST elevation and 13% for ST depression. ST...

2011-01-01

23

Prenatal diagnosis and perinatal management of left coronary artery to right atrium fistula.  

Science.gov (United States)

Serious complications due to coronary artery fistulae have been described. Most authors recommend early intervention at the time of diagnosis. We present a case of a fistula originating from a dilated left coronary artery and draining into the right atrium, which was diagnosed prenatally by color Doppler echocardiography. During pregnancy, the echocardiographic findings remained unchanged, and there were no signs of heart failure. After birth, the fistula was confirmed by angiography. Additionally, a persistent left superior vena cava draining into the coronary sinus and a very small ventricular septal defect were detected. The fistula was closed successfully by transcatheter coil embolization. At 17 months old the child was in good clinical condition. Prenatal diagnosis of coronary artery fistulae may be possible and may improve perinatal management and outcome. PMID:12047543

2002-06-01

24

SUPPLEMENTAL COLUMBIA RIVER PROTECTION ACTIVITIES AT THE DEPARTMENT OF ENERGY HANFORD SITE: 2006 TECHNICAL PEER REVIEW  

Energy Technology Data Exchange (ETDEWEB)

Prompted by a $10 million Congressional allocation to identify supplemental actions to protect the Columbia River from groundwater contamination beneath the Hanford Reservation, the U. S. Department of Energy (DOE) Environmental Management (EM) Office of Clean-up Technology identified twenty-three potential technical projects and then down-selected ten of these for further evaluation. An independent expert peer review was conducted for the ten down-selected proposals. The review panel consisted of twenty-three recognized subject matter experts that broadly represented academia, industry, and federal laboratories. Of the initial ten proposals reviewed, one was given unconditional support, six were given conditional support, and three were not supported as proposed. Three additional proposals were then submitted by DOE for review--these proposals were structured, in part, to respond to the initial round of technical peer ...

2006-12-20

25

Possible global environmental impacts of solid waste practices  

Energy Technology Data Exchange (ETDEWEB)

Pollutants resulting from the management of solid waste have been shown to affect the air, land, oceans, and waterways. In addition, solid wastes have other, more indirect impacts such as reduction in feedstocks of natural resources, because useful materials are disposed of rather than recycled. The objective of this study is to evaluate solid waste management practices that have negative implications on the global environment and develop recommendations for reducing such impacts. Recommendations identifying needed changes are identified that will reduce global impacts of solid waste practices in the future. The scope of this study includes the range of non-hazardous solid wastes produced within our society, including municipal solid waste (MSW) and industrial solid waste (ISW), as well as industry-specific wastes from activities such as construction, demolition, and landclearing. Most solid waste management decisions continue to be made and ...

1994-09-01

26

Teachers' perceptions of epilepsy.  

UK PubMed Central (United Kingdom)

A questionnaire survey undertaken among 142 schoolteachers in North Staffordshire revealed most of the respondents did not feel confident when teaching children who had epilepsy and a minority considered...Full Text Available

1992-12-01

27

Specialist clinics: a better way to care?  

UK PubMed Central (United Kingdom)

A questionnaire on the development of specialist clinics was distributed to the members of the Association of British Neurologists and completed by 104 members (85 consultants). Half of the respondents...Full Text Available

1992-03-01

28

Skin as an endocrine organ: implications for its function  

UK PubMed Central (United Kingdom)

Described as the body's largest organ, the skin is strategically located at the interface with the external environment where it has evolved to detect, integrate and respond to a diverse range...Full Text Available

2008-06-01

29

Rapidly adapting receptors in a rabbit model of mitral regurgitation  

UK PubMed Central (United Kingdom)

Unlike in normal rabbits, pulmonary rapidly adapting receptors (RARs) in rabbits with chronic mitral regurgitation (MR) do not respond to small changes in extravascular...Full Text Available

1999-12-15

30

Orthopedic Anesthesia in Haiti  

UK PubMed Central (United Kingdom)

Healthcare practitioners from around the world responded almost immediately in the aftermath of the 2010 earthquake in Haiti. This article reports on the efforts of an orthopedic trauma team in Haiti...Full Text Available

2011-01-01

31

NASA - NASA, National Academies Team On Space Exploration Vision  

Science.gov (United States)

Jul 15, 2004 ... Responding to the recommendations of the President's Commission on Implementation of United States Space Exploration Policy, NASA is teaming ...

32

Layout 1  

Wastenet

Competitiveness of the UK furniture manufacturing industry.2010 ...is clear from the study that the UK furniture manufacturing industry has responded to the challenge of ...Competitiveness of the UK furniture manufacturing industry.2010

33

Affective Distress and Amputation-Related Pain Among Older Men with Long-Term, Traumatic Limb Amputations  

British Library Electronic Table of Contents (United Kingdom)

Psychological distress and postamputation pain were investigated in a sample of 582 males with long-term limb amputations (mean time since amputation 639.3 months, standard deviation 166.1; range 240-784 months). Prevalence of significant depressive symptoms (Hospital Anxiety and Depression Scale [HADS]-D score?8) was 32.0%, and 34.0% of respondents met the screening criterion for clinical anxiety (HADS-A score?8). Nearly one quarter (24.6%) of respondents reported significant post-traumatic psychological stress symptoms (Impact of Event Scale scores?35). In total, 87.8% experienced either phantom or residual limb pain. Affective distress scores differed according to the respondents' type of pain experience. Respondents who experienced residual limb pain reported significantly hig...

2006-01-01

34

Telecommunications Network Plan  

International Nuclear Information System (INIS)

The Office of Civilian Radioactive Waste Management (OCRWM) must, among other things, be equipped to readily produce, file, store, access, retrieve, and transfer a wide variety of technical and institutional data and information. The data and information regularly produced by members of the OCRWM Program supports, and will continue to support, a wide range of program activities. Some of the more important of these information communication-related activities include: supporting the preparation, submittal, and review of a license application to the Nuclear Regulatory Commission (NRC) to authorize the construction of a geologic repository; responding to requests for information from parties affected by and/or interested in the program; and providing evidence of compliance with all relevant Federal, State, local, and Indian Tribe regulations, statutes, and/or treaties. The OCRWM Telecommunications Network Plan (TNP) is intended to identify, as ...

1997-10-07

35

Online grocery retailing: What do consumers think?  

DEFF Research Database (Denmark)

Purpose: To use the theory of planned behavior (TPB) as a theoretical framework to explore in depth the range of beliefs held by consumers about internet shopping in general and internet grocery shopping in particular. Design/methodology/approach: Seven focus group interviews, four in the United Kingdom and three in Denmark, were conducted among consumers with different degrees of experience with internet grocery shopping. This diversification of respondents was chosen to capture a broad range of the consumer beliefs that predict intentions to buy groceries online or not. The TPB framework was used to construct the interview guide that was followed in all focus groups. Findings: An unexpected result of the explorative study was that the seven groups consisting of more or less experienced internet shoppers differed only little in their pool of beliefs (outcome and control beliefs). Beliefs about internet grocery shopping, positive as well as negative, were ...

2005-01-01

36

Allowance trading under the Clean Air Act: Who should regulate, and when?  

Energy Technology Data Exchange (ETDEWEB)

The goal of this paper is to explore how compliance with the Clean Air Act Amendments of 1990 (CAAA), especially Title IV and emission trading under it, will affect the current relationship between state and federal regulation. It is difficult, with the limited experience we have had under Title IV, to be definitive about or to be a very strong advocate of too many policy positions. What may be most helpful at this point is to identify where the difficult issues in state/federal relations might arise; and then to explore ways in which tensions might be either avoided or resolved. One anticipated conclusion is that a traditional regulatory mindset could be very destructive if applied to this new area of oversight without due sensitivity to what Congress is trying to achieve in Title IV. That concern pervaded the early legislative debates; and it persists today. Title IV presents some unique challenges to state regulators and will require some creative solutions and ...

1993-07-01

37

A randomized trial of microdose leuprolide acetate protocol versus luteal phase ganirelix protocol in predicted poor responders  

British Library Electronic Table of Contents (United Kingdom)

We performed a randomized trial to compare IVF outcomes in 54 poor responder patients undergoing a microdose leuprolide acetate (LA) protocol or a GnRH antagonist protocol incorporating a luteal phase E2 patch and GnRH antagonist in the preceding menstrual cycle. Cancellation rates, number of oocytes retrieved, clinical pregnancy rates (PR), and ongoing PRs were similar between the two groups.

2011-01-01

38

Automated Critical Peak Pricing Field Tests: Program Descriptionand Results  

Energy Technology Data Exchange (ETDEWEB)

California utilities have been exploring the use of critical peak prices (CPP) to help reduce needle peaks in customer end-use loads. CPP is a form of price-responsive demand response (DR). Recent experience has shown that customers have limited knowledge of how to operate their facilities in order to reduce their electricity costs under CPP (Quantum 2004). While the lack of knowledge about how to develop and implement DR control strategies is a barrier to participation in DR programs like CPP, another barrier is the lack of automation of DR systems. During 2003 and 2004, the PIER Demand Response Research Center (DRRC) conducted a series of tests of fully automated electric demand response (Auto-DR) at 18 facilities. Overall, the average of the site-specific average coincident demand reductions was 8% from a variety of building types and facilities. Many electricity customers have suggested that automation will help them institutionalize their electric demand savings and improve their ...

2006-04-06

39

Virtual adult ears reveal the roles of acoustical factors and experience in auditory space map development  

UK PubMed Central (United Kingdom)

Auditory neurons in the superior colliculus (SC) respond preferentially to sounds from restricted directions to form a map of auditory space. The development of this representation is shaped...Full Text Available

2008-11-05

40

Trichoderma atroviride G-Protein ?-Subunit Gene tga1 Is Involved in Mycoparasitic Coiling and Conidiation  

UK PubMed Central (United Kingdom)

The soil fungus Trichoderma atroviride, a mycoparasite, responds to a number of external stimuli. In the presence of a fungal host, T. atroviride produces...Full Text Available

2002-08-01

41

Treatment of atypical depression with cognitive therapy or phenelzine: a double-blind, placebo-controlled trial.  

UK PubMed Central (United Kingdom)

Background: Patients with a typical depression are more likely to respond to monoamine oxidase inhibitors than to tricyclic antidepressants. They are frequently offered psychotherapy...Full Text Available

1999-05-01

42

Transcatheter stent implantation to treat aortic coarctation in infancy.  

UK PubMed Central (United Kingdom)

A ten week old girl who had previously undergone a palliative procedure for the hypoplastic left heart syndrome had unrelieved aortic coarctation that did not respond to standard balloon dilatation....Full Text Available

1993-01-01

43

Thermosensitive TRP channel pore turret is part of the temperature activation pathway  

UK PubMed Central (United Kingdom)

Temperature sensing is crucial for homeotherms, including human beings, to maintain a stable body core temperature and respond to the ambient environment. A group of exquisitely temperature-sensitive...Full Text Available

2010-04-13

44

The QseC Adrenergic Signaling Cascade in Enterohemorrhagic E. coli (EHEC)  

UK PubMed Central (United Kingdom)

The ability to respond to stress is at the core of an organism's survival. The hormones epinephrine and norepinephrine play a central role in stress responses in mammals, which require the synchronized...Full Text Available

2009-08-01

45

The Functional Role of Calcineurin in Hypertrophy, Regeneration, and Disorders of Skeletal Muscle  

UK PubMed Central (United Kingdom)

Skeletal muscle uses calcium as a second messenger to respond and adapt to environmental stimuli. Elevations in intracellular calcium levels activate calcineurin, a serine/threonine phosphatase, resulting...Full Text Available

2010-01-01

46

Teaching safe and effective prescribing in UK medical schools: a core curriculum for tomorrow's doctors  

UK PubMed Central (United Kingdom)

There is a pressing need for medical graduates to be fully prepared to take on the responsibilities of prescribing and to be able to respond to continual inevitable rapid changes in therapeutics. The...Full Text Available

2003-06-01

47

Synchrony between orientation-selective neurons is modulated during adaptation-induced plasticity in cat visual cortex  

UK PubMed Central (United Kingdom)

BackgroundVisual neurons respond essentially to luminance variations occurring within their receptive fields. In primary visual cortex, each neuron is a filter for stimulus features...Full Text Available

48

Responding to the Medical Malpractice Insurance Crisis: A National Risk Management Information System  

UK PubMed Central (United Kingdom)

In the process of forming a new medical malpractice reinsurance company, the authors analyzed thousands of medical malpractice cases, settlements, and verdicts. The evidence of those analyses indicated...Full Text Available

1987-11-04

49

Resistance to sexual assault: who resists and what happens?  

UK PubMed Central (United Kingdom)

To determine who resists sexual assault and what happens, data were examined from a probability sample of 3,132 adult community residents of Los Angeles, California. Seventy-five per cent of the respondents...Full Text Available

1989-01-01

50

Raiders of the Lost Bark: Orangutan Foraging Strategies in a Degraded Landscape  

UK PubMed Central (United Kingdom)

Deforestation is rapidly transforming primary forests across the tropics into human-dominated landscapes. Consequently, conservationists need to understand how different taxa respond and adapt to these...Full Text Available

51

Normal human B lymphocytes and mononuclear cells respond to the mitogenic and cytokine-stimulatory activities of Borrelia burgdorferi and its lipoprotein OspA.  

UK PubMed Central (United Kingdom)

Borrelia burgdorferi produces potent cell-activating molecules capable of stimulating polyclonal proliferation and immunoglobulin production by murine B lymphocytes and cytokine production by a variety...Full Text Available

1994-02-01

52

NASA/DOD Aerospace Knowledge Diffusion Research Project. Phase 2: Respondents Including Frequency Distributions.  

Science.gov (United States)

Phase 2 of the four phase NASA/DoD Aerospace Knowledge Diffusion Research Project was undertaken to study the transfer of scientific and technical information (STI) from government to the aerospace industry and the role of librarians and technical informa...

1991-01-01

53

Multivariate analyses reveal common and drug specific genetic influences on responses to four drugs of abuse  

UK PubMed Central (United Kingdom)

Vulnerability to abused drugs is influenced by multiple genes unique to each drug as well as to risk genes for polydrug abuse. If several inbred mouse strains respond to different drugs similarly,...Full Text Available

2008-11-01

54

Modulation of the human hair follicle pigmentary unit by corticotropin-releasing hormone and urocortin peptides  

UK PubMed Central (United Kingdom)

Human skin is a local source of corticotropin-releasing hormone (CRH) and expresses CRH and CRH receptors (CRH-R) at mRNA and protein levels. Epidermal melanocytes respond to CRH by induction...Full Text Available

2006-05-01

55

Modulation of leg muscle function in response to altered demand for body support and forward propulsion during walking  

UK PubMed Central (United Kingdom)

A number of studies have examined the functional roles of individual muscles during normal walking, but few studies have examined which are the primary muscles that respond to changes in external...Full Text Available

2009-05-11

56

Melanopsin-expressing retinal ganglion-cell photoreceptors: cellular diversity and role in pattern vision  

UK PubMed Central (United Kingdom)

Using the photopigment melanopsin, intrinsically photosensitive retinal ganglion cells (ipRGCs) respond directly to light to drive circadian clock resetting and pupillary constriction. We now...Full Text Available

2010-07-15

57

Life on the edge: carnivore body size variation is all over the place  

UK PubMed Central (United Kingdom)

Evolutionary biologists have long been fascinated by both the ways in which species respond to ecological conditions at the edges of their geographic ranges and the way that species' body sizes evolve...Full Text Available

2009-04-22

58

Labeled lines meet and talk: population coding of somatic sensations  

UK PubMed Central (United Kingdom)

The somatic sensory system responds to stimuli of distinct modalities, including touch, pain, itch, and temperature sensitivity. In the past century, great progress has been made in understanding the...Full Text Available

2010-11-01

59

Exceptional sensitivity of testicular germ cell tumour cell lines to the new anti-cancer agent, temozolomide.  

UK PubMed Central (United Kingdom)

Metastatic testicular germ cell tumours are cured in approximately 85% of patients using cisplatin-based combination chemotherapy. Patients who fail to respond have a poor prognosis, and there is a...Full Text Available

1995-05-01

60

Effect of a reminder video using a mobile phone on the retention of CPR and AED skills in lay responders.  

Science.gov (United States)

BACKGROUND: : Skills related to cardiopulmonary resuscitation (CPR) and automated external defibrillator (AED) use by lay responders decay rapidly after training, and efforts are required to maintain competence among trainees. We examined whether repeated viewing of a reminder video on a mobile phone would be an effective means of maintaining CPR and AED skills in lay responders. METHODS: : In a single-blind case-control study, 75 male students received training in CPR and AED use. They were allocated either to the control or to the video-reminded group, who received a memory card containing a video clip about CPR and AED use for their mobile phone, which they were repeatedly encouraged to watch by SMS text message. CPR and AED skills were assessed in scenario format by examiners immediately and 3 months after initial training. RESULTS: : Three months after initial training, the video-reminded group showed more accurate airway opening (PCPR ...

2011-09-26

61

Effect of NAD+ on Malate Oxidation in Intact Plant Mitochondria 1  

UK PubMed Central (United Kingdom)

Potato tuber mitochondria oxidizing malate respond to NAD+ addition with increased oxidation rates, whereas mung bean hypocotyl mitochondria do not. This is traced to a low endogenous content...Full Text Available

1980-08-01

62

Does It Matter What You Measure? Neighbourhood Effects in a Canadian Setting  

UK PubMed Central (United Kingdom)

Data from 8,032 Manitoba respondents to the 1996/97 Canadian National Population Health Survey were linked to the 1996 census to study whether measures of morbidity, both self-reported and objectively...Full Text Available

2010-08-01

63

Differential effects of the mottled yellow and pseudoagouti phenotypes on immunocompetence in Avy/a mice.  

UK PubMed Central (United Kingdom)

Whereas genetic factors are known to influence both susceptibility to carcinogens and the capacity to respond to specific antigenic stimuli, little is known regarding the influence of phenotype per...Full Text Available

1984-04-01

64

Dendritic Signals Command Firing Dynamics in a Mathematical Model of Cerebellar Purkinje Cells  

UK PubMed Central (United Kingdom)

AbstractDendrites of cerebellar Purkinje cells (PCs) respond to brief excitations from parallel fibers with lasting plateau depolarizations. It is unknown whether these plateaus are local...Full Text Available

2010-07-21

65

Delayed choice responding by pigeons when the correct response is not predictable from the sample stimulus.  

UK PubMed Central (United Kingdom)

Food-deprived pigeons were presented with a row of four response keys situated above a grain hopper aperture. At the start of a trial, three of four keys were randomly selected and illuminated white...Full Text Available

1982-01-01

66

Cytoplasmic Calcium Increases in Response to Changes in the Gravity Vector in Hypocotyls and Petioles of Arabidopsis Seedlings1  

UK PubMed Central (United Kingdom)

Plants respond to a large variety of environmental signals, including changes in the gravity vector (gravistimulation). In Arabidopsis (Arabidopsis thaliana) seedlings, gravistimulation...Full Text Available

2008-02-01

67

Comparing and Contrasting the Roles of AMPK and SIRT1 in Metabolic Tissues  

UK PubMed Central (United Kingdom)

The ability to adapt and respond to nutrients is an ancient cellular function, conserved from unicellular to the most complex multicellular organisms, including mammals. Mammals adapt to changes...Full Text Available

2008-12-01

68

Carrier-mediated Potassium Efflux Across the Cell Membrane of Red Beet  

UK PubMed Central (United Kingdom)

The flux ratio (influx/efflux) of K+ across the plasmalemma of beet cells at an external potassium concentration of 0.6 mm does not respond to changes of membrane potential in the...Full Text Available

1969-04-01

69

Astronaut Jeff Williams Answers Your Questions  

National Aeronautics and Space Administration (NASA)

Expedition 22 Commander Jeff Williams, aboard the International Space Station 220 miles above Earth, responds to questions posted on YouTube concerning the station's orientation, life in space and the recent butterfly experiment.

2010-03-10

70

Angular distribution of environmental radiation incident on humans; and reply  

International Nuclear Information System (INIS)

A brief letter attempts to justify the assumption in an earlier paper of an isotropic distribution of environmental gamma rays incident on humans. A second letter from the original authors responds to this in yet more detail. (UK).

71

MRI in the diagnosis of non-compacted ventricular Myocardium (NCVM) compared to echocardiography  

International Nuclear Information System (INIS)

Purpose: To report the detection of con-compacted ventricular myocardium (NVCM) with MRI compared to echocardiography in 8 patients. Material and methods: Non-compaction of the ventricular myocardium is a congenital disorder characterized by an altered structure of the myocardial wall resulting from an intrauterine arrest in endomyocardial embryogenesis. The morphological findings consist of a prominent meshwork of multiple myocardial trabeculations and deep intertrabecular recesses, communicating with the left ventricular cavity. 8 consecutive patients (mean age 7.3 years) with clinical and echocardiographic signs of NCVM were examined by MRI (1.5 T, Vision, Siemens) in short axis and 2- and 4-chamber views, using T_1-weighted TSE and Cine-GRE in 6 patients and true FISP sequences in 2 patients. MRI and echocardiography were evaluated for visibility, signs of NCVM and involvement of myocardial wall segments. Thickness was measured for non-compacted and compacted ...

2003-09-01

72

Psychological factors affecting public acceptance of nuclear energy. Comparative analysis focusing on regional characteristics and degree of knowledge  

International Nuclear Information System (INIS)

The purpose of this research is to clarify how psychological factors' impact on public acceptance of nuclear energy varies with where they live and their degree of knowledge. For this purpose, we carried out questionnaire survey about nuclear energy at three urban areas and two nuclear power plant siting areas. After collecting data, we applied factor analysis to the data, and found four factors which construct cognitive structure of nuclear energy. Using multiple regression analysis, we evaluated the impact of the four factors on two issues: the decision for or against nuclear policy and the reaction to nuclear power plant siting, and compared changes of the impact by where respondents live and their degree of knowledge. Consequently, we found that the impact of all four factors on the two issues varies with where respondents live. We also found that the impact of respondents' degree of knowledge to four factors varies ...

2003-12-01

73

Photobiology and photosynthesis  

British Library Electronic Table of Contents (United Kingdom)

To test the hypothesis that leaf level photosynthetic related traits might confer late successionals a competitive advantage over early successionals in low light growth conditions, steady photosynthetic assimilation and dynamic photosynthetic induction related traits were examined in low light grown seedlings with contrasting successional status. Compared with the early successionals, late successionals as a group significantly exhibited lower leaf gas exchange rates. While late successionals required a longer time to respond to simulated sunflecks, they had lower rates of induction losses after sunflecks. Such photosynthetic induction traits allowed late successionals to more effectively utilize subsequent sunflecks. It was observed that plants with lower gas exchange rates responded mor...

2011-01-01

74

Host plant odor extracts with strong effects on oviposition behavior in Papilio polyxenes  

British Library Electronic Table of Contents (United Kingdom)

Abstract Ovipositing females of the black swallowtail butterfly, Papilio polyxenes Fabricius (Lepidoptera: Papilionidae: Papilioninae), have an innate response to contact chemical cues, but it was not known how naive females would respond to volatile host plant chemicals. Naive and experienced females were tested in a free-flight experiment using model plants and volatile extracts from two hosts, carrot [Daucus carota L. (Apiaceae)] and poison hemlock [Conium maculatum L. (Apiaceae)], and one non-host, fava bean [Vicia faba L. (Fabaceae)]. Naive females responded to both host plant extracts with more approaches and landings than to non-host extracts, with poison hemlock receiving more responses than carrot. Females experienced with one of the two host plants also approached and landed freq...

2008-01-01

75

Energy value as a factor of agroforestry wood species selectivity in Akinyele and Ido local government areas of Oyo State, Nigeria  

British Library Electronic Table of Contents (United Kingdom)

Wood usage for cooking and heating is still very relevant in most developing countries especially those of sub-Saharan Africa and many parts of Asia. Therefore, sustainable means of generating it for this and other purposes are necessary bearing in mind the influence of indigenous knowledge/users perspective on any production method regarding success and sustenance. In conformity with this view, questionnaires were administered on 240 respondents in 8 rural communities of Akinyele and Ido Local Government Areas (LGAs) of Oyo State, Nigeria, to elicit information on species that can be used as fuelwood, preferred by the respondents for incorporation into and/or retention in agroforestry plots, out of which 179 (i.e. 75% of the total number of questionnaires administered) were successfully r...

2009-01-01

76

An empirical analysis of factors affecting adolescent attachment in adoptive families with homosexual and straight parents  

British Library Electronic Table of Contents (United Kingdom)

Data were collected on 154 adoptive families with gay/lesbian and straight adoptive parents (154 parent respondents and 210 adolescent respondents). This study was principally interested in factors affecting adolescent attachment including parent sexual orientation, adolescent and parent life satisfaction, and parent level of relationship satisfaction with their adopted child as well as other key parent, child and adoption characteristics. The results suggest that higher level of adopted adolescent attachment to parents is not related to adoptive parent sexual orientation. Adolescent attachment to parents is related to adolescent life satisfaction; parent level of relationship satisfaction with their adopted child, number of placements prior to adoption, and adolescent's current age. Adole...

2009-01-01

79

Uncertainty analysis of high altitude aircraft air mass zero solar cell calibration  

Energy Technology Data Exchange (ETDEWEB)

Recently the ISO standards organization has requested the PV community to establish AMO calibration methodologies for space solar cells. The PV community responded by organizing a series of workshops to review and recommend AMO calibration techniques. One of the activities of the workshop is to review the various calibration methodologies and conduct a comprehensive uncertainty analysis of each method. This paper outlines NASA`s methodology of AMO calibration using the high altitude aircraft method.

1997-12-31

80

The mGluR2 Positive Allosteric Modulator BINA Decreases Cocaine Self-Administration and Cue-Induced Cocaine-Seeking and Counteracts Cocaine-Induced Enhancement of Brain Reward Function in Rats  

UK PubMed Central (United Kingdom)

Metabotropic glutamate receptor 2/3 (mGluR2/3) agonists were shown previously to nonselectively decrease both cocaine- and food-maintained responding in rats. mGluR2 positive allosteric modulators (PAMs)...Full Text Available

2010-09-01

81

Questionnaire based survey of general population to assess their views about disclosure of cancer diagnosis and review of literature  

International Nuclear Information System (INIS)

Objective: To ascertain people's views regarding disclosure of cancer diagnosis and whether they would like to share this information with their family. The study also looked at whether if their parents were diagnosed to be suffering from cancer, would they like this information to be communicated to them. Results: The total number of persons surveyed were 520. Fifteen persons refused to participate in the survey, hence they were excluded and 505 respondents 299 male and 206 female were analyzed. Ages of the respondents were between 18 to 80 years. The study population belonged to different socio-economic groups in the society. Three hundred ninety-one (77.4%) responded positively that they would like to know if they ever suffer from cancer, while 112 (22.1%) said No and 2 (0.39%) said it doesn't matter. Three hundred seventeen (62.7%) wanted their family to be informed while 187 (37.%) said No and the attitude of 1 (0.19%) ...

2003-01-01

82

Pericardio-peritoneal drainage using a subcostal approach.  

Science.gov (United States)

A 56-year-old man admitted to our hospital for cardiac tamponade due to dilated cardiomyopathy did not respond to treatment by usual medical means or surgery. Pericardio-peritoneal drainage was conducted using a subcostal approach. Seven months later, the patient remains well and free of signs of pericardial tamponade. This method has proved to be safe and effective in patients with persistent massive pericardial effusion. PMID:10496067

1999-08-01

83

Nuclear energy - an option for Croatian sustainable development  

International Nuclear Information System (INIS)

The uncertainties of growth in Croatian future energy, particularly electricity demand, together with growing environmental considerations and protection constraints, are such that Croatia needs to have flexibility to respond by having the option of expanding the nuclear sector. The paper deals with nuclear energy as an option for croatian sustainable economic development. The conclusion is that there is a necessity for extended use of nuclear energy in Croatia because most certainly nuclear energy can provide energy necessary to sustain progress. (author).

1996-10-07

84

Nonhuman primates will not respond to turn off strong 60 Hz electric fields  

Energy Technology Data Exchange (ETDEWEB)

Using a set of six baboons (Papio cynocephalus), the authors conducted a series of seven experiments designed to evaluate the potentially aversive character of a 60 Hz electric field (EF). Initially, the subjects were trained, using food rewards as the reinforcer, to respond only when a cue light was illuminated. Next, an EF was presented along with the cue light; responses produced delivery of a food pellet and turned off both the cue light and the EF. Then, stimulus and reward conditions were varied. The authors determined that (1) presence of a strong EF does not affect operant responding for food rewards, (2) subjects will not respond at normal rates when the only reinforcer is termination of a strong EF, (3) presence of a strong EF can serve as a discriminative stimulus, (4) presence of a strong EF does not affect extinction of an appetite-motivated task, and (5) presentation of an EF can become a secondary reinforcer. ...

1995-12-31

85

NAME=\\  

Wastenet

... All rickettsial diseases respond to treatment with antibiotics such as doxycycline and tetracycline As of 10 May, the Government of South Africa has reported 186 confirmed cases of RVF in humans, including 18 deaths, in Free State Province, Eastern Cape Province, Northern Cape Province, Western Cape, and North West Province. RVF is a viral disease that primarily affects animals (such as cattle, buffalo, sheep, goats and camels). The disease can also affect humans. The main mode of transmission of RVF ...

86

Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor ?-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of ?-Catenin Signaling*  

UK PubMed Central (United Kingdom)

The capacity of bones to adjust their mass and architecture to withstand the loads of everyday activity derives from the ability of their resident cells to respond appropriately to the strains engendered....Full Text Available

2010-03-19

87

How can the EU respond to Kazakhstan'  

Wastenet

... The final strand is to invest in new infrastructure, supporting the growth of small and medium-sized businesses and developing new productive industries like pharmaceuticals, locomotive engineering and plastics. Having acted as an adviser to the government, I can see several reasons why the EU should welcome and support this model of economic development. The most important is that Kazakhstan's diversification and its determination to move production up the ...

88

Device for the inspection of curved pipes in steam raising units  

Energy Technology Data Exchange (ETDEWEB)

The chain of eddy current probes and a film cassette probe, which responds to radiation from a radio-active source in one of the heat exchanger pipes is examined. The probes are moved by nylon pipes on both ends of the chain through the pipe to be examined. The nylon pipes are bent off load. In this way the probes on the chain will adjust near to the plane of bending of the pipes to be tested.

1980-01-03

89

Depth profile of uncompensated spins in an exchange bias system  

Energy Technology Data Exchange (ETDEWEB)

We have used the unique spatial sensitivity of polarized neutron and soft x-ray beams in reflection geometry to measure the depth dependence of magnetization across the interface between a ferromagnet and antiferromagnet. The new uncompensated magnetization near the interface responds to applied field, while the uncompensated spins in the antiferromagnetic bulk are pinned, thus providing a means to establish exchange bias.

2005-05-17

90

Bullous pemphigoid after radiation therapy  

Energy Technology Data Exchange (ETDEWEB)

Electron beam therapy applied to a lymph node metastasis from a squamous cell carcinoma was followed by the development of histologically and immunologically typical bullous pemphigoid, the lesions being initially strictly confined to the irradiation area. This observation suggests that the bullous pemphigoid antigen may be altered or unmasked by electron beam radiotherapy, leading subsequently to the production of autoantibodies. The disease in this case effectively responded to the administration of tetracycline and niacinamide, a therapeutic regimen described recently.

1988-02-01

91

Beyond Boomer Meets NextGen: Examining Mentoring Practices among Pennsylvania Academic Librarians  

British Library Electronic Table of Contents (United Kingdom)

A survey to assess mentoring experiences and attitudes towards work of Pennsylvania academic librarians was conducted in September 2006 with questions concerning mentoring experiences, work experiences, and attitudes towards work. Results of the survey are analyzed for differences among those librarians responding, especially generational differences, and implications for professional associations when developing mentoring programs are discussed.

2011-01-01

92

A High Throughput Combinatorial Library Technique for Identifying Formalin-Sensitive Epitopes  

UK PubMed Central (United Kingdom)

We present a technique for identifying the amino acids responsible for a loss of immunoreactivity in response to treating an antigen with a chemical modifier. This is of particular interest...Full Text Available

2006-12-20

93

Ecological response of a multi-purpose river development project using macro-invertebrates richness and fish habitat value  

International Nuclear Information System (INIS)

It has been acknowledged that river morphology and hydrology have been intensively altered due to the anthropic demands in floodplain land use and management, flood protection, promotion of navigability or energy production. Rivers were transformed in water highways, having lost contact with their surrounding floodplain as well as the plethora of ecological processes and occupants once thriving in these ecotonal zones. The identification of this emerging threat of morphological and hydrological alteration on ecological integrity adds further complexity in the exploitation of hydrosystem resources. These resources are heavily coveted and guarded by different lobbies each having strategic views on future project development. Stakeholders may want to promote hydro-electricity, ecologists a natural reserve, communes may wish to have an increased flood protection and leisure promoters a nautical center. As a result, the proposition of a river development project is certain to face ...

2002-04-01

94

Valuing climate protection through willingness to pay for biomass ethanol  

Energy Technology Data Exchange (ETDEWEB)

This study uses a multi-part, split-sample contingent valuation method (CVM) and fair share (FS) survey to better understand the public's valuation of mitigating global climate change through its willingness to pay for biomass or 'cellulosic' ethanol. In addition to a basic CVM question, a related scenario was developed that asked half of the survey respondents to state their fair share cost to lessen a potential food shortage in the next decade, also through the expanded use of cellulosic ethanol. Three alternative biomass feedstocks were assessed: farming residues, forestry residues and paper mill wastes, and municipal solid wastes. Overall a slightly larger proportion of respondents were WTP extra for cellulosic ethanol in the basic CVM scenario than in the FS scenario, though no significant differences were found in the WTP for the different feedstocks. Bid curve lognormal regression results for the two models ...

2009-05-15

95

The treatment of chronic pain by epidural spinal cord stimulation--a 15 year follow up; present status.  

Science.gov (United States)

Pain is necessary for survival but chronic pain is disabling and causes significant health and economic problems. This study provides an understanding of the future for spinal cord stimulation. Stimulation by means of chronically implanted electrodes, was carried out in 200 patients with pain of varied benign organic etiology. In 177 of them, pain was confined to the failed back syndrome. Most patients were referred by a Pain Management Service. 226 epidural implants were used: 80 unipolar, 59 Resume, 12 bipolar, and 75 quadripolar. Patients were followed for periods of 6 months to 12 years, with a mean follow-up of 44 months. 84 patients (42%) were able to control their pain by stimulation alone, 22 patients (11%) needed occasional analgesic supplements along with their stimulation program. Pain secondary to failed back syndrome, multiple sclerosis, peripheral vascular disease, sympathetic dystrophy and diabetic neuropathy responded favorably. Pain due to cauda ...

1997-06-01

96

The requirement for sodium as a micronutrient by species having the c(4) dicarboxylic photosynthetic pathway.  

Science.gov (United States)

Six species having characteristics of plants with the C(4) dicarboxylic photosynthetic pathway, Echinochloa utilis L. Ohwi et Yabuno (Japanese millet), Cynodon dactylon L. (Bermuda grass), Kyllinga brevifolia Rottb., Amaranthus tricolor L. cv. Early splendour, Kochia childsii Hort., and Portulaca grandiflora Hook (rose moss), responded decisively to 0.1 milliequivalent per liter NaCl supplied to their culture solutions initially containing less than 0.08 microequivalent per liter Na. Chlorosis and necrosis occurred in leaves of plants not receiving sodium. Portulaca failed to set flower in the sodium-deficient cultures. Under similar conditions Poa pratensis L. (Kentucky blue grass) having characteristics of the C(3) photosynthetic pathway made normal growth and did not respond to the addition of sodium. It is concluded from these results and previously reported work that sodium is generally essential for species having the C(4) pathway but not ...

1972-05-01

97

The Requirement for Sodium as a Micronutrient by Species Having the C4 Dicarboxylic Photosynthetic Pathway  

Science.gov (United States)

Six species having characteristics of plants with the C4 dicarboxylic photosynthetic pathway, Echinochloa utilis L. Ohwi et Yabuno (Japanese millet), Cynodon dactylon L. (Bermuda grass), Kyllinga brevifolia Rottb., Amaranthus tricolor L. cv. Early splendour, Kochia childsii Hort., and Portulaca grandiflora Hook (rose moss), responded decisively to 0.1 milliequivalent per liter NaCl supplied to their culture solutions initially containing less than 0.08 microequivalent per liter Na. Chlorosis and necrosis occurred in leaves of plants not receiving sodium. Portulaca failed to set flower in the sodium-deficient cultures. Under similar conditions Poa pratensis L. (Kentucky blue grass) having characteristics of the C3 photosynthetic pathway made normal growth and did not respond to the addition of sodium. It is concluded from these results and previously reported work that sodium is generally essential for species having the C4 pathway but not for ...

1972-01-01

98

The 1992 Pacific Northwest Residential Energy Survey : Phase 1 (PNWRES92-I) : Book 12 : Non-Respondent Survey.  

Energy Technology Data Exchange (ETDEWEB)

This book constitutes a portion of the primary documentation for the 1992 Pacific Northwest Residential Energy Survey, Phase I. The complete 33-volume set of primary documentation provides information needed by energy analysts and interpreters with respect to planning, execution, data collection, and data management of the PNWRES92-I process. Thirty of these volumes are devoted to different ``views`` of the data themselves, with each view having a special purpose or interest as its focus. Analyses and interpretations of these data will be the subjects of forthcoming publications. Conducted during the late summer and fall months of 1992, PNWRES92-I had the over-arching goal of satisfying basic requirements for a variety of information about the stock of residential units in Bonneville`s service region. Surveys with a similar goal were conducted in 1979 and 1983. This volume contains a follow-up study of non-respondents to the original survey. The information is ...

1993-08-01

99

Responses to ammonium and nitrate additions by boreal plants and their natural enemies  

Energy Technology Data Exchange (ETDEWEB)

Separate effects of ammonium (NH{sub 4} {sup +}) and nitrate (NO{sub 3} {sup -}) on boreal forest understorey vegetation were investigated in an experiment where 12.5 and 50.0 kg nitrogen (N) ha{sup -1} year{sup -1} was added to 2 m{sup 2} sized plots during 4 years. The dwarf-shrubs dominating the plant community, Vaccinium myrtillus and V. vitis-idaea, took up little of the added N independent of the chemical form, and their growth did not respond to the N treatments. The grass Deschampsia flexuosa increased from the N additions and most so in response to NO{sub 3} {sup -}. Bryophytes took up predominately NH{sub 4} {sup +} and there was a negative correlation between moss N concentration and abundance. Plant pathogenic fungi increased from the N additions, but showed no differences in response to the two N forms. Because the relative contribution of NH{sub 4} {sup +} and NO{sub 3} {sup -} to the total N deposition on a regional scale can vary substantially, the ...

2006-05-15

100

Mutations in cyr1 and pat1 reveal pheromone-induced G1 arrest in the fission yeast Schizosaccharomyces pombe  

DEFF Research Database (Denmark)

Investigations into sexual differentiation and pheromone response in the fission yeast Schizosaccharomyces pombe are complicated by the need to first starve the cells of nitrogen. Most mating-related experiments are therefore performed on non-dividing cells. Here we overcome this problem by using two mutants that bypass the nutritional requirements and respond to the M-factor mating pheromone in rich medium. The first mutant lacks the cyr1 gene which encodes adenylate cyclase and these cells contain no measurable amounts of cAMP. When M-factor is added to a growing h+ cyr1- strain it causes a transient G1 arrest of cell division, transcription of mat1-Pm, and elongation of the cells to form shmoos. The second mutant contains the temperature-sensitive pat1-114 allele. At 30 degrees C this mutant was previously shown not only to bypass the nutritional signal but also to stop growing in a state derepressed for pheromone-controlled functions. We now report that an h+ ...

1994-01-01

101

Government response to public consultation. Offshore natural gas storage and liquefied natural gas import facilities  

Energy Technology Data Exchange (ETDEWEB)

As its indigenous gas supplies decline, the UK will need to import more gas. In November 2006, the Department of Trade and Industry issued a consultation on revising the consent regime for offshore gas storage and offshore liquefied natural gas unloading. A total of 27 responses had been received by the closing date of 16 February 2007 from a variety of interest parties including developers and their representative organisations, consultants, environmental organisations, maritime organisations, heritage organisations and other public bodies. This report presents the Government's response to the views expressed by these respondents. The majority of respondents supported the Government's proposals to put in place new legislation to permit offshore gas storage activities. Many believed new legislation was necessary to provide the legal certainty necessary ro encourage offshore development and investment in such developments. ...

2007-05-15

102

Evidence for divided automatic attention  

Scientific Electronic Library Online (English)

Abstract in english A long-standing debate in the literature is whether attention can form two or more independent spatial foci in addition to the well-known unique spatial focus. There is evidence that voluntary visual attention divides in space. The possibility that this also occurs for automatic visual attention was investigated here. Thirty-six female volunteers were tested. In each trial, a prime stimulus was presented in the left or right visual hemifield. This stimulus was characteriz (more) ed by the blinking of a superior, middle or inferior ring, the blinking of all these rings, or the blinking of the superior and inferior rings. A target stimulus to which the volunteer should respond with the same side hand or a target stimulus to which she should not respond was presented 100 ms later in a primed location, a location between two primed locations or a location in the contralateral hemifield. Reaction time to the positive target ...

2008-02-01

103

Effects of the cannabinoid antagonist SR141716 (rimonabant) and d-amphetamine on palatable food and food pellet intake in non-human primates  

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study was to determine if a cannabinoid CB1 receptor antagonist would selectively decrease consumption of highly palatable food in non-human primates. The CB1 receptor antagonist SR141716 (rimonabant; 0.12?1.0?mg/kg, i.m.) and the stimulant anorectic drug d-amphetamine (0.12?1.0?mg/kg, i.m.) were administered to non-food deprived baboons for the purpose of measuring the effect of each drug on consumption of the normal diet, and a large single meal of a high-carbohydrate candy. Four male and four female baboons had access to food 24?h each day, but they had to complete a two phase operant procedure in order to eat. Responding on one lever during a 30-min appetitive phase was required before animals could start a consumption phase, where responding on another lever led to...

2007-01-01

104

Changes in Sea-Level Pressure over South Korea Associated with High-Speed Solar Wind Events  

CERN Document Server

We explore a possibility that the daily sea-level pressure (SLP) over South Korea responds to the high-speed solar wind event. This is of interest in two aspects: First, if there is a statistical association this can be another piece of evidence showing that various meteorological observables indeed respond to variations in the interplanetary environment. Second, this can be a very crucial observational constraint since most models proposed so far are expected to preferentially work in higher latitude regions than the low latitude region studied here. We have examined daily solar wind speed ${\\rm V}$, daily SLP difference ${\\rm \\Delta SLP}$, and daily ${\\rm \\log(BV^{2})}$ using the superposed epoch analysis in which the key date is set such that the daily solar wind speed exceeds 800 ${\\rm kms^{-1}}$. We find that the daily ${\\rm \\Delta SLP}$ averaged out of 12 events reaches its peak at day +1 and gradually decreases back to its normal ...

2011-01-01

105

?Tasting and wasting?? behavior in non-human primates: Aberrant behavior or normal behavior in ?times of plenty??  

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study was to develop a foraging model that engenders large meals. Eight free-feeding baboons were first given periodic access to a chocolate sugar-coated candy (M & Ms?) and then a jelly sugar-coated candy (Skittles?). Baboons had access to food 24?h each day, but they had to complete a two-phase operant procedure in order to eat. Responding on one lever during a 30-min appetitive phase was required before animals could start a consumption phase, where responding on another lever led to food delivery, i.e., a meal. 3?days a week for 8 or 9?weeks baboons received candy during the first meal and then food pellets were available: a 2?month interval when only pellets were available separated periods of candy access. All baboons ate as much candy in the single candy meal as ...

2006-01-01

106

The Dynamic Analog Scale: A generic method for single-item measurement  

British Library Electronic Table of Contents (United Kingdom)

The Dynamic Analog Scale (DAS) is introduced as a technique for generating single-item measures of personality traits. The DAS is comprised of extensive trait definitions and an analog scale on which respondents simultaneously rate themselves and others. In two studies the Big Five personality traits were assessed with the DAS and compared to a multiple-item questionnaire that measured the same traits. Statistical analysis supported the validity of the DAS for predicting self-reported behavioral acts, drinking behaviors, affect, and religiosity in ways similar to the multiple-item questionnaire. Consistent with previous research, both studies supported the viability of measuring personality traits with single items.

2011-01-01

107

Some reflections on the network power plant interaction  

International Nuclear Information System (INIS)

The layout of the network with its frequency and transmission power control shows how the time behaviour of power plants and consumers determines the frequency curve during sudden power disturbances. As for switching processes in the network for the turbine, network operation entails loads due to shock-like disturbance functions to which one should not normally respond by switching off. The interception controllers are therefore adjusted via a simulation model by which the vibrations of the turbine rotor can be modelled in real time under different network loads. (GL).

1978-11-24

108

Solar energy receiver for a Stirling engine  

Energy Technology Data Exchange (ETDEWEB)

A solar energy receiver is described including a separable endless wall formed of a ceramic material having defined therein a cavity of a substantially cylindrical configuration for entrapping solar flux, and an acceptance aperture adapted to admit to the cavity a concentrated beam of solar energy, said wall being characterized by at least a pair of contiguously related segments separated by lines of cleavage intercepting said aperture, at least one of the segments being supported for pivotal displacement, and a thermal responsive actuator adapted to respond to excessive temperatures within the cavity for initiating pivotal displacement of said one segment, whereby thermal flux is permitted to escape from the cavity.

1980-12-02

109

Research on Nanosecond Pulse Corona Discharge Attenuation  

Science.gov (United States)

A line-to-plate reactor was set-up in the experimental study on the application of nanosecond pulsed corona discharge plasma technology in environmental pollution control. Investigation on the attenuation and distortion of the amplitude of the pulse wave front and the discharge image as well as the waveform along the corona wire was conducted. The results show that the wave front decreases sharply during the corona discharge along the corona wire. The higher the amplitude of the applied pulse is, the more the amplitude of the wave front decreased. The wave attenuation responds in a lower corona discharge inversely. To get a higher efficiency of the line-to-plate reactor a sharp attenuation of the corona has to be considered in practical design.

2007-12-01

110

NRC safety research in support of regulation, 1986  

Energy Technology Data Exchange (ETDEWEB)

This report is the second in a series of annual reports responding to congressional inquiries as to the utilization of nuclear regulatory research. NUREG-1175, ''NRC Safety Research in Support of Regulation,'' published in May 1986, reported major research accomplishments between about FY 1980 and FY 1985. This report narrates the accomplishments of FY 1986 and does not restate earlier accomplishments. Earlier research results are mentioned in the context of current results in the interest of continuity. Both the direct contributions to scientific and technical knowledge and their regulatory applications, when there has been a definite regulatory outcome during FY 1986, have been described.

1987-09-01

111

Modified-VSIMM algorithm with an application to the naval fire control technology  

British Library Electronic Table of Contents (United Kingdom)

A modified variable structure interacting multiple model (M-VSIMM) estimator for complex hybrid maneuver target tracking is presented. The M-VSIMM could potentially be applied to fire control systems (FCS) used on warships. Target model groups were designed using 3D dimensional dynamic target models. Optimal model group selection logic was proposed, contrary to the activation and termination logic in the original VSIMM. The system will respond faster with optimal model group selection logic. After performing simulations, the tracking performances of the Kalman, ?-?(-?), VDIE, IMM and M-VSIMM filters were compared under various maneuvering conditions.

2011-01-01

112

Material-not-categorized-as-waste survey for 1992  

Energy Technology Data Exchange (ETDEWEB)

In October 1992, the US Department of Energy, Richland Field Office (RL) requested that Westinghouse Hanford Company (WHC) respond to a letter from EM-331 asking for completion of a survey of items in storage but not categorized as waste (Roberts 1992). The letter contained an attachment with instructions on how to fill out the attached form and what to exclude from the survey (Appendix A). This report is a summary of the information from the response issued to RL. This report primarily is for use in estimating future waste volumes that may have been overlooked because of the nature of their classification as material not categorized as waste (MNCAW) (i.e., not yet declared Waste).

1993-07-01

113

Inhaled toluene produces pentobarbital-like discriminative stimulus effects in mice  

Science.gov (United States)

The abuse of volatile solvents may be due to their ability to produce an intoxication similar to that produced by classical central nervous system depressants such as the barbiturates and ethanol. To evaluate this hypothesis, mice were trained to discriminate pentobarbital from saline injections in a two-lever operant task. Stimulus generalization was examined following 20-min inhalation exposures to toluene (300-5400 ppm). In 8 of 10 subjects, pentobarbital-lever responding occurred following toluene exposure indicating an overlap in the discriminative stimulus properties of toluene and pentobarbital.

1985-10-07

114

Energy value as a factor of agroforestry wood species selectivity in Akinyele and Ido local government areas of Oyo State, Nigeria  

Energy Technology Data Exchange (ETDEWEB)

Wood usage for cooking and heating is still very relevant in most developing countries especially those of sub-Saharan Africa and many parts of Asia. Therefore, sustainable means of generating it for this and other purposes are necessary bearing in mind the influence of indigenous knowledge/users' perspective on any production method regarding success and sustenance. In conformity with this view, questionnaires were administered on 240 respondents in 8 rural communities of Akinyele and Ido Local Government Areas (LGAs) of Oyo State, Nigeria, to elicit information on species that can be used as fuelwood, preferred by the respondents for incorporation into and/or retention in agroforestry plots, out of which 179 (i.e. 75% of the total number of questionnaires administered) were successfully retrieved for statistical analyses. Twelve woody species namely: Annona senegalensis, Anogeissus leiocarpus, Bridelia ferruginea, Daniellia oliveri, ...

2009-10-15

115

Energy production: institutional and legislative scenario  

Energy Technology Data Exchange (ETDEWEB)

Brief comments are given on the evolution of the institutional nature of ENEL (Italian Electricity Board) as it relates to the framework of legislation for the nationalization of the utility in December, 1962. Special attention is given to the development of legislative criteria to allow the creation of a rate structure, in the case of autoproduction by industry, that would stimulate national economic growth. A discussion is also made of the changing role of ENEL as it responds to the planning objectives cited in the Italian National Energy Plan which calls for a more integrated effort by the regional governments and the Electricity Board in the management of natural resources.

1989-05-01

116

Autonomic Management of Maintenance Scheduling in Chord  

CERN Document Server

This paper experimentally evaluates the effects of applying autonomic management to the scheduling of maintenance operations in a deployed Chord network, for various membership churn and workload patterns. Two versions of an autonomic management policy were compared with a static configuration. The autonomic policies varied with respect to the aggressiveness with which they responded to peer access error rates and to wasted maintenance operations. In most experiments, significant improvements due to autonomic management were observed in the performance of routing operations and the quantity of data transmitted between network members. Of the autonomic policies, the more aggressive version gave slightly better results.

2010-01-01

117

A study on the response time characteristics related to shock control in the hydraulic system using the fluid device  

International Nuclear Information System (INIS)

Control of pressure transients in a hydraulic system may be important and necessary to avoid failures and to improve the efficiency of operation. Flow restricting devices can result in a decrease in the peak pressure, but may change the response time. The response time has an important effect on both operator and operator perceived smoothness. The response time should correspond to how fast a system responds to a given disturbance at the system boundary. Occasionally the appropriate response time is not easily determined. This study is on the response time characteristics in the hydraulic system studied for the control of response time.

2001-11-01

118

A study on reliability of electro-hydraulic governor control system for large steam turbine in power plant  

Energy Technology Data Exchange (ETDEWEB)

In this work, the right management procedure for hydraulic power oil will be discussed and suggested. A thermal power plant turbine should respond to the change of load status. However, to satisfy the frequency of alternating current, the revolution per minute should be kept constant. Therefore, by controlling the flow rate of the steam to the turbine, the governor satisfies the load variation without alternating the revolution per minutes of the turbine. To protect the governor, the hydraulic power unit should be managed carefully by controlling the quality and the flow rate of the oil.

2008-07-01

119

Social modeling in the transmission of suicidality.  

Science.gov (United States)

Evidence from twin, adoption, and family studies suggests that there is strong aggregation of suicidal behaviors in some families. By comparison, the role of social modeling through peers has yet to be convincingly established. This paper uses data from four large studies (the WHO/EURO Multicentre Study on Suicidal Behaviour, the WHO/SUPRE-MISS, the CASE study, and the Queensland Suicide Register) to compare the effects of exposure to fatal and nonfatal suicidal behavior in family members and nonfamilial associates on the subsequent suicidal behavior of male and female respondents of different ages. Across all studies, we found that prior suicidal behaviors among respondents' social groups were more important predictors of suicidal behavior in the respondents themselves than previous research had indicated. Community-based suicide attempters in the WHO SUPRE-MISS had higher rates of exposure to prior suicide in nonfamilial ...

2008-01-01

120

Repeated laboratory ozone exposures of volunteer Los Angeles residents: an apparent seasonal variation in response  

Energy Technology Data Exchange (ETDEWEB)

This study was intended to help explain individual differences in susceptibility to irritant effects of ozone (O3), by determining whether prior ambient O3 exposures and/or recent acute respiratory illness modified response to laboratory O3 exposures. Response was measured in terms of lung function changes and irritant symptoms. Initially, 59 adult volunteer Los Angeles area residents underwent screening exposures in spring, before the season of frequent high ambient O3 levels. Unusually responsive and nonresponsive individuals (N = 12 and 13 respectively) underwent followup exposures in autumn (late in the high-O3 season) and in winter (low-O3 season). All exposures were to 0.18 ppm O3 for 2 hr with intermittent heavy exercise at 31 degrees C and 35% relative humidity. Nonresponders tended to remain nonresponsive throughout. In fall, responders had lost much of their reactivity, as if they had adapted to summer ambient O3 exposures. They did not regain reactivity ...

1988-12-01

121

Medical treatment of nystagmus and ocular motor disorders.  

Science.gov (United States)

An increased compendium of drugs useful in ocular motor system dysfunction has expanded our capacity to treat selected ocular motility disorders. Adjunctive therapeutic modes (e.g., Fresnel prisms and orthoptic exercises) can also be beneficial. PAN and see-saw nystagmus can be treated with baclofen. Downbeat nystagmus may respond to clonazepam therapy, and prisms may help if the nystagmus can be modified with convergence. Congenital nystagmus may respond minimally to drugs (e.g., baclofen), but prisms or surgical procedures, or both, are still the primary treatment modalities. Innovar may be helpful in patients with severe, incapacitating vestibular disorders, and scopolamine alone or in combination with promethazine may be beneficial in patients with milder ambulatory acute peripheral vestibular disorders. Benign positional vertigo is best treated initially with positional exercises before drug therapy is instituted. Opsoclonus and ocular ...

1986-01-01

122

Illinois department of public health H1N1/A pandemic communications evaluation survey.  

Energy Technology Data Exchange (ETDEWEB)

Because of heightened media coverage, a 24-hour news cycle and the potential miscommunication of health messages across all levels of government during the onset of the H1N1 influenza outbreak in spring 2009, the Illinois Department of Public Health (IDPH) decided to evaluate its H1N1 influenza A communications system. IDPH wanted to confirm its disease information and instructions were helping stakeholders prepare for and respond to a novel influenza outbreak. In addition, the time commitment involved in preparing, issuing, monitoring, updating, and responding to H1N1 federal guidelines/updates and media stories became a heavy burden for IDPH staff. The process and results of the H1N1 messaging survey represent a best practice that other health departments and emergency management agencies can replicate to improve coordination efforts with stakeholder groups during both emergency preparedness and response phases. Importantly, the H1N1 survey ...

2010-09-16

125

Willingness to pay for energy-saving measures in residential buildings  

Energy Technology Data Exchange (ETDEWEB)

This paper uses a choice experiment to evaluate the consumers' willingness to pay for energy-saving measures in Switzerland's residential buildings. These measures include air renewal (ventilation) systems and insulation of windows and facades. Two groups of respondents consisting respectively of 163 apartment tenants and 142 house owners were asked to choose between their housing status quo and each one of the several hypothetical situations with different attributes and prices. The estimation method is based on a fixed-effects logit model. The results suggest that the benefits of the energy-saving attributes are significantly valued by the consumers. These benefits include both individual energy savings and environmental benefits as well as comfort benefits namely, thermal comfort, air quality and noise protection. (author)

2008-03-15

126

Viewpoint: Space System Negation in the Context of Space Policy and Law  

British Library Electronic Table of Contents (United Kingdom)

For 21st century warfare, space is the unquestioned new high ground for military operations. The United States (U.S.) has relied on satellites for significant support to military operations and activities since Desert Storm in 1991. Indeed, the U.S. enjoys an asymmetric advantage in modern warfare utilizing our space capabilities. States with interests hostile to the U.S. believe that the significant dependence on space assets by the U.S. military could become its "Achilles heel" in future combat operations. What are the legal and policy bases for the U.S. to respond to threats to space systems that provide support to our military forces? Should the U.S. rely on space arms control initiatives to ensure security in space? This Viewpoint analyzes the international space law regime and U.S. N...

2007-01-01

127

Upper limb dysfunction following selective neck dissection: A retrospective questionnaire study  

British Library Electronic Table of Contents (United Kingdom)

Background. To determine total upper limb function following selective neck dissection over a mean follow-up of 1.6 years. Methods. A retrospective questionnaire study in a tertiary head and neck surgical unit. One hundred forty-eight patients who underwent selective neck dissection for head and neck cancer from January 2000 to December 2005 were invited to participate. The main outcome measure was ipsilateral upper limb dysfunction as measured by the Disability of Arm, Shoulder and Hand (DASH) questionnaire. Results. Sixty-five patients responded to the invitation to join the study from 148 invited. Despite accessory nerve conserving surgery for all the selective neck dissections studied, 23% reported no upper limb dysfunction, 54% reported mild upper limb dysfunction, 15% reported modera...

2009-01-01

128

Undergraduate Instruction in Empirical Research Methods in Communication: Assessment and Recommendations  

British Library Electronic Table of Contents (United Kingdom)

This study assesses the current state of undergraduate instruction in empirical research methods in communication and offers recommendations for enhancing such instruction. Responses to an online questionnaire were received from 149 communication-related programs at four-year colleges and universities. Just over 85% of responding programs offered an empirical methods course. Although the course often covered both qualitative and quantitative methods, instruction was heavily slanted toward quantitative methods and topics common to both qualitative and quantitative inquiry. The empirical methods course was usually required for graduation, but it was typically not well integrated with the rest of the curriculum and taken late in students' undergraduate careers. Additional analyses examined st...

2011-01-01

129

The role of Multidetector CT in the evaluation of the left atrium and pulmonary veins anatomy before and after radio-frequency catheter ablation for atrial fibrillation. Preliminary results and work in progress.Technical note  

International Nuclear Information System (INIS)

Radio-frequency catheter ablation (RFCA) of the distal pulmonary veins is increasingly being used to treat recurrent or refractory atrial fibrillation that doesn't respond to pharmacologic therapy or cardioversion. Successful RFCA of atrial al fibrillation depends on the pre-procedural understanding of the complex anatomy of the distal pulmonary veins and the left atrium. Aim of this parer is to describe the technical main features that characterise the multidetector helical computed tomography in the evaluation of this anatomic region before and after RFCA procedure. The 3D post-processing techniques useful for pre-RFCA planning are straightforward.

130

South African consumers' opinions and consumption of soy and soy products  

British Library Electronic Table of Contents (United Kingdom)

Abstract Interest in soy foods has increased with consumer awareness of its health benefits, especially with soy-related ingredients being utilized as one of the major sources of high-protein fortification. The aim of the present study was to assess South African (SA) consumers' opinion of soy and soy products through different statements on consumption, taste, protein value and healthiness. The respondents (n = 3001) for this randomized cross-sectional study were randomly selected from metropolitan and rural areas in South Africa. Trained fieldworkers administered questionnaires by conducting face-to-face interviews. Fourteen statements from four sections of the questionnaire (consisting of 17 food-related topics in total), probing information on consumers' opinion on soy and soy products...

2009-01-01

131

Seductions of Risk and School Cyberspace  

Science.gov (United States)

Drawing upon the cultural risk perspective and writings on risk taking, this paper seeks to develop ideas relating to the effective use of school cyberspace. It is argued that some individuals respond to exaggerated, yet seductive, discourses of online risks by over-blocking, unreasonably restricting students' Internet activity. At the same time, there are sensible, even compelling, motivations for teachers as well as students to use the school Internet to engage in low-level risk taking, fostering excitement, identity construction and networked media literacy. Connecting these seductive pushes and pulls of risk it is ultimately maintained that the fostering of trust through open communication is key in overcoming over-blocking whilst allowing for greater educational gains, realised in part through certain types of low-level risk taking in school cyberspace.

2009-12-01

132

Roles and challenges of the health information management educator: a national HIM faculty survey.  

Science.gov (United States)

Health information technology initiatives created the framework for a national health information infrastructure that concomitantly fostered a need to build intellectual capacity within our current and future health information management (HIM) work force. Results from the 2008 HIM Educator Survey are discussed. Developed for voluntary electronic participation, the survey comprised a series of questions about educators' professional interests and responsibilities. Summary data from the 402 respondents are provided and highlight areas such as academic rank, teaching status, salary range, levels of interest in various issues, and use of virtual learning tools. Data from this survey provide insights into the concerns and challenges many HIM educators face in today's training institutions and suggest implications for future directions in work force training and professional development within the HIM field. PMID:19424453

2009-04-30

133

Response to measles-mumps-rubella vaccine in children on dialysis.  

Science.gov (United States)

Ten children receiving maintenance dialysis were immunized with the standard dose of measles-mumps-rubella vaccine between 15 and 33 months of age. Immune responses to vaccination were determined using commercially available enzyme-linked immunosorbent assays for measles, mumps, and rubella viruses. Eight children responded to measles vaccine, 5 to mumps vaccine, 8 to rubella vaccine, and only 3 children to all three vaccines, compared with a seroconversion rate of over 90% to all three vaccines in healthy children (P less than 0.0001). We contend that the relatively poor immunocompetence of our dialysis patients explains their less than optimal vaccine response and suggest that children vaccinated while undergoing dialysis be tested to confirm serological evidence of immunity. PMID:1571219

1992-03-01

134

Responding to diversity: the challenge of expanding basic education for young people in the south  

British Library Electronic Table of Contents (United Kingdom)

This article explores the extent to which and how non-formal education (NFE) contributes to the development of a more diversified basic education system and thus to the achievement of EFA. It outlines the current nature of NFE, the frameworks provided by the EFA movement, and the evolution of reflection, policies and practices in NFE in relation to basic education as a whole. Based on significant developments in various countries across the South, the article also discusses some key challenges that ministries of education and their partners need to face in moving towards relevant and equitable diversity in education. The article posits that, despite the many problems faced by NFE, there is justification for building on its experiences and integrating these within a larger policy and system...

2008-01-01

135

Researching ethnic minority students in a Chinese context: mixed methods design for cross cultural understandings  

British Library Electronic Table of Contents (United Kingdom)

Research on and with ethnic minority students is characterised by a growing international literature that privileges 'liberal multiculturalism' as a lens through which to understand their experiences, yet ethnic diversity is constructed and responded to in many societies that are not underpinned by liberal democratic values. In this paper we use Joppke's binary to show how researching ethnic minority students outside of a liberal democratic framework requires methodologies that enable researchers to see beyond the invisibility that is often attached to ethnic minorities. We show how invisibility (i.e. antidiscrimination) can also be further culturally constructed, confounding even more any broader multicultural project. We canvass four broad areas including the role of legally binding legi...

2011-01-01

136

Renewable Energy in Danish Municipalities - an Evaluation of The Planning Framework for Wind Power  

DEFF Research Database (Denmark)

Wind power is a maturing technology that in a number of countries is likely to contribute a major share to fully renewable energy systems. Denmark has a comparably long history of wind power development and is planning to continue expanding the existing capacity. If a large-scale penetration of wind power is to be achieved, an integrated framework is needed that can respond to the associated challenges. This paper argues for adopting an integrated macro perspective when evaluating and building frameworks to support wind power development. This macro perspective is applied to the case of Denmark, and more specifically to concrete wind power projects in the region of Northern Jutland. The results suggest although certain elements in the legislation have been improved, the feasibility of wind power projects cannot be guaranteed, and there is a tendency to exclude smaller turbines from the development.

2009-01-01

137

Real-time configuration changes of the ATLAS High Level Trigger  

CERN Document Server

The ATLAS High Level Trigger (HLT) is a distributed real-time software system that performs the final online selection of events produced during proton-proton collisions at the Large Hadron Collider (LHC). It is designed as a two-stage trigger and event filter running on a farm of commodity PC hardware. Currently the system consists of about 850 processing nodes and will be extended incrementally following the expected increase in luminosity of the LHC to about 2000 nodes. The event selection within the HLT applications is carried out by specialized reconstruction algorithms. The selection can be controlled via properties that are stored in a central database and are retrieved at the startup of the HLT processes, which then usually run continuously for many hours. To be able to respond to changes in the LHC beam conditions, it is essential that the algorithms can be re-configured without disrupting data taking while ensuring a consistent and reproducible ...

2010-01-01

138

Protoplanetary Disks of Binary Systems in Orion  

CERN Document Server

Dusty primordial disks surrounding young low-mass stars are revealing tracers of stellar and planetary formation. The evolution and lifetime of these disks define the boundary conditions of the mechanisms of planet formation. Stellar companions, however, can significantly change this evolution through their tidal interactions. Stellar evolution and planet formation in binaries have to respond to an environment of truncated, quickly disappearing disks--very different compared to an isolated star environment. In order to investigate details of the influence of binarity on circumstellar disk evolution, we obtained adaptive optics supported near-infrared imaging and spectroscopy of the individual components of 22 low-mass binaries in the well-known Orion Nebula Cluster. Brackett gamma emission, which we detect in several systems, is used as a tracer for the presence of an active accretion disk around each binary component. We find a low fraction of accreting binary ...

2010-01-01

139

Media Choice in Environmental Information Dissemination for Solid Waste Management among Policy Formulators and Implementors: A Case Study of Oyo State, Nigeria  

British Library Electronic Table of Contents (United Kingdom)

Environmental information has been described as central to the issues of solid waste management and disposal. This study investigated the availability and accessibility of environmental information to the solid waste policy formulators and implementors with regard to the media/channels used for disseminating environmental information to the public. A descriptive survey design was adopted for the study. A purposive sampling technique was used to select the sample and the method produced 205 respondents that consisted of 185 Policy Implementors and 20 Policy Formulators. A total of 147 cases were finally analyzed, which included 16 Policy Formulators (80% of total sample) and 131 Policy Implementors (71% of total sample). Data collected were analyzed using descriptive statistics such as perc...

2009-01-01

140

Male meadow voles respond differently to risk and intensity of sperm competition  

British Library Electronic Table of Contents (United Kingdom)

There are 2 models of male adjustment of sperm investment in the ejaculate in relation to sperm competition. The "risk model" predicts that as "risk" of sperm competition increases, sperm investment also increases. This prediction has been supported in many species, including mammals. The "intensity model" involves the number of competing males copulating with the same female and predicts that males will allocate the highest sperm investment at low sperm competition intensity (SCI) and then decreasing sperm investments as SCI increases. Two alternative outcomes are that sperm investment is unaffected by SCI and that sperm investment increases as SCI increases. There are studies supporting all 3 possible outcomes in relation to SCI but no data on mammals. The present paper presents the firs...

2006-01-01

141

Lugworm exclusion experiment: Responses by deposit feeding worms to biogenic habitat transformations  

British Library Electronic Table of Contents (United Kingdom)

On six 400 m2 plots over 3 years, we excluded the sessile subduction and conveyer-belt feeding polychaete Arenicola marina which generates a pit-and-mound topography at the sediment surface from intertidal sands near the island of Sylt, Germany. This experiment was used to test whether other abundant deposit feeding polychaetes (the discretely motile and surface feeding ragworm Nereis diversicolor and the subsurface-feeding, motile orbiniid polychaete Scoloplos cf. armiger) benefit from competitive release. Ragworms took advantage from the absence of lugworms. Presumably they responded to a more stable and nutritious surface layer at lugworm exclusion plots (relief from inhibitive bioturbation). Contrary to this, S. cf. armiger was negatively affected by the exclusion of A. marina. It may ...

2006-01-01

142

Layer- and cell-type-specific suprathreshold stimulus representation in rat primary somatosensory cortex  

British Library Electronic Table of Contents (United Kingdom)

Sensory stimuli are encoded differently across cortical layers and it is unknown how response characteristics relate to the morphological identity of responding cells. We therefore juxtasomally recorded action potential (AP) patterns from excitatory cells in layer (L) 2/3, L4, L5 and L6 of rat barrel cortex in response to a standard stimulus (e.g. repeated deflection of single whiskers in the caudal direction). Subsequent single-cell filling with biocytin allowed for post hoc identification of recorded cells. We report three major conclusions. First, sensory-evoked responses were layer- and cell-type-specific but always

2007-01-01

143

Impacts of increased fire frequency and aridity on eucalypt forest structure, biomass and composition in southwest Australia  

British Library Electronic Table of Contents (United Kingdom)

Water stress and fire disturbance can directly impact stand structure, biomass and composition by causing mortality and influencing competitive interactions among trees. However, open eucalypt forests of southwest Australia are highly resilient to fire and drought and may respond differently to increased fire frequency and aridity than forests dominated by non-eucalypt species. We measured the variation in stem density, basal area, stand biomass, sapwood area, leaf area and litterfall across 16 mixed jarrah (Eucalyptus marginata) and marri (Corymbia calophylla) forest stands along an aridity gradient in southwest Australia that had variable fire histories. Fire frequency was defined as the total number of fires over a ~30-year period and aridity as the ratio of potential evapotranspiration...

2009-01-01

144

Idaho Explosives Detection System  

Energy Technology Data Exchange (ETDEWEB)

The Idaho Explosives Detection System was developed at the Idaho National Laboratory (INL) to respond to threats imposed by delivery trucks potentially carrying explosives into military bases. A full-scale prototype system has been built and is currently undergoing testing. The system consists of two racks, one on each side of a subject vehicle. Each rack includes a neutron generator and an array of NaI detectors. The two neutron generators are pulsed and synchronized. A laptop computer controls the entire system. The control software is easily operable by minimally trained staff. The system was developed to detect explosives in a medium size truck within a 5-min measurement time. System performance was successfully demonstrated with explosives at the INL in June 2004 and at Andrews Air Force Base in July 2004.

2005-12-01

145

Hystersisters Online: Social Support and Social Comparison Among Hysterectomy Patients on the Internet  

British Library Electronic Table of Contents (United Kingdom)

Background: The Internet has become a popular source of health information for patients with a variety of medical concerns; however, research examining patient interactions on the Internet has been limited. Purpose: Four questions were examined in a survey study of hysterectomy patients who visited http://www.hystersisters.com: (a) Do hysterectomy patients use the support Web site because they perceive their proximal sources of social support to be inadequate? (b) What kinds of support do patients receive from the Web site? (c) What attributes characterize the "Hystersisters" that are perceived to be most helpful? (d) How do informational sources vary depending on the nature of the patient concern? Methods: Women (N = 137) responded to questions about social support, Web site use, and perc...

2006-01-01

146

Housing development finance through cooperative societies: The case of Ogbomoso, Nigeria  

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to investigate the contribution of cooperative societies to housing finance for the urban low income group in Ogbomoso, Oyo state of Nigeria. This is with a view to determine the effectiveness of the societies' lending as a means of solving the housing problem among the low income group in Nigeria. Design/methodology/approach - Questionnaires were administered to 120 members of eight societies of four cooperative unions selected through a random sampling technique. In total, 15 members who had benefited from the loan were surveyed in each of the societies. Data were analysed with the use of frequency distribution, percentage and measure of cooperators satisfaction index (CSI). Findings - The results showed that 52 per cent of responding members had fi...

2010-01-01

147

High-speed wide area, data intensive computing: A Ten Year Retrospective  

Energy Technology Data Exchange (ETDEWEB)

Modern scientific computing involves organizing, moving, visualizing, and analyzing massive amounts of data from around the world, as well as employing large-scale computation. The distributed systems that solve large-scale problems will always involve aggregating and scheduling many resources. Data must be located and staged, cache and network capacity must be available at the same time as computing capacity, etc. Every aspect of such a system is dynamic: locating and scheduling resources, adapting running application systems to availability and congestion in the middleware and infrastructure, responding to human interaction, etc. The technologies, the middleware services, and the architectures that are used to build useful high-speed, wide area distributed systems, constitute the field of data intensive computing. This paper explores some of the history and future directions of that field.

1998-05-01

148

Hazardous-waste disposal and the clinical laboratory. Final report, May-December 1989  

Energy Technology Data Exchange (ETDEWEB)

Negligent hazardous waste management has resulted in real threats to public health. The Federal Government has responded to the situation with laws and regulations aimed at the producers of hazardous waste, including clinical laboratories. The Resources Conservation and Recovery Act (RCRA) imposes controls on hazardous waste management through the Code of Federal Regulations (CFR). The Environmental Protection Agency (EPA) and the Department of Transportation (DOT) regulate these activities through 40 CFR and 49 CFR. Most clinical laboratories can operate satellite accumulation points and accumulate, store, transport, and dispose of waste in accordance with EPA and DOT regulations. Regulations pertaining to infectious waste, sure to affect many clinical laboratories, are being developed now by he EPA. The cradle to grave tracking system mandated by the Federal Government can be supplemented by state and local authorities and poses a significant regulatory challenge ...

1990-01-01

149

Expert judgement of uncertainties in modelling emergency actions after nuclear accidents  

Energy Technology Data Exchange (ETDEWEB)

Sheltering, evacuation and distribution of stable iodine tablets are considered to be major early emergency actions aiming at diminishing the consequences after a release of radioactive materials from nuclear power plants into the air. Whether in real situations emergency managers will act accordingly is hard to predict. Uncertainties associated with these decisions are termed 'volitional' uncertainties. These uncertainties, however, cannot be assessed by expert judgements as they express the decision at stake in an emergency situation. Uncertainties on the times to implement countermeasures and on the times for the general population to respond to these measures can be assessed by experts, as they represent 'lack-of-knowledge' uncertainties. This paper describes the difference in approach of both types of uncertainties and shows the results of expert judgements on the latter type of uncertainties in early emergency actions. Ten ...

2000-07-01

150

Evaluation of the non-formal forest education sector in the state of North Rhine-Westphalia, Germany: organisations, programmes and framework conditions  

British Library Electronic Table of Contents (United Kingdom)

Although a large number of different organisations offer various forest education programmes within Germany, specific information (i.e., sectoral and programme content and provision at a state level) is lacking. This study used a survey of all 61 forest education organisations (43 respondents) in the state of North Rhine-Westphalia, Germany, to evaluate its forest education sector, with a specific focus on the organisations, demand for its services, forest educational programmes and framework conditions. Input from expert interviews was also used to develop recommendations. The study indicates that, especially with children as the main target group, many non-formal programmes are offered to support the formal environmental education sector and to promote leisure activities in the forest. Y...

2011-01-01

151

Education qualification levels and school careers of unilateral versus bilateral hearing aid users  

British Library Electronic Table of Contents (United Kingdom)

Objective: Analyse the difference in school careers and secondary school qualification levels between unilateral hearing aid users and bilateral hearing aid users. Study design: Retrospective questionnaire study. Setting: Postal-based questionnaire. Participants: Names of adults known to have been fitted with unilateral or bilateral hearing aids during childhood were retrieved. This resulted in 292 names. Participants were selected using the following criteria: availability of the medical record, presence of bilateral hearing loss, completed secondary school education, normal IQ and a minimum aided word-recognition score of 70% at 10 years of age. The questionnaire was sent to 50 potential participants of whom 40 responded, resulting in two groups comprising 19 unilateral and 21 bilateral ...

2007-01-01

152

Differential facilitative and competitive effects of a dominant macrophyte in grazed subtropical wetlands  

British Library Electronic Table of Contents (United Kingdom)

Summary 1.-Plant-plant interactions fluctuate between competition and facilitation depending upon ecological conditions and species traits. Facilitative interactions are expected to increase in frequency via associational defences with increasing consumer pressure. The ability of species to cope with competition and/or ecological stressors may alter the outcome of plant-plant interactions. 2.-We conducted a transplant experiment to determine if native and non-native grasses and forbs respond similarly to interactions with Juncus effusus L., an unpalatable benefactor species, along a grazing intensity gradient in two contrasting pasture types: intensively managed and semi-natural. We expected competitive taller, erect species (grasses) and non-natives to obtain stronger facilitative effects...

2011-01-01

153

Contingency plan for the Lawrence Livermore National Laboratory's hazardous-waste operations  

Energy Technology Data Exchange (ETDEWEB)

The Lawrence Livermore National Laboratory (LLNL) has the necessary equipment and trained personnel to respond to a large number of hazardous material spills and fires or other emergencies resulting from these spills including injured personnel. This response capability is further expanded by the agreements that LLNL has with a number of outside response agencies. The Hazards Control Department at LLNL functions as the central point for coordinating the response of the equipment and personnel. Emergencies involving hazardous waste are also coordinated through the Hazards Control Department, but the equipment and personnel in the Toxic Waste Control Group would be activated for large volume waste pumpouts. Descriptions of response equipment, hazardous waste locations communication systems, and procedures for personnel involved in the emergency are provided.

1981-03-20

154

Consumer demand for 'green power' and energy efficiency  

Energy Technology Data Exchange (ETDEWEB)

This article examines reported willingness to pay for electric utility investments in renewable energy and energy efficiency resources using the results of Deliberative Polls conducted by electric utilities in Texas. Age, education, and salary tend to affect reported willingness to pay for utility investments in these resources. Intensive exposure to information about energy resource issues led to an increase in the number of respondents interested in paying a modest premium to support investments in both renewable energy resources and energy efficiency. However, average reported premiums actually declined following the Polls, as very high outlier responses moved to more reasonable values following the Polls. These results support the contention that informed dialogue about energy alternatives will result in broader interest in providing a modest level of support for these resources. (author)

2003-12-01

155

Chondrocytes and bone marrow-derived mesenchymal stem cells undergoing chondrogenesis in agarose hydrogels of solid and channelled architectures respond differentially to dynamic culture conditions  

British Library Electronic Table of Contents (United Kingdom)

Abstract The objective of this study was to investigate how a combination of different scaffold architectures and rotational culture would influence the functional properties of thick cartilaginous tissues engineered using either chondrocytes or bone marrow-derived mesenchymal stem cells (BM-MSCs). Expanded porcine chondrocytes and BM-MSCs were suspended in 2% agarose and cast in custom-designed moulds to produce either regular solid or channelled construct cylinders. The study consisted of three seperate experimental arms. First, chondrocyte and BM-MSC constructs were cultured in free swelling conditions for 9 weeks. Second, constructs were subjected to rotational culture for a period of 3 weeks. Finally, BM-MSC-seeded constructs were subjected to delayed rotational culture, in which cons...

2011-01-01

156

Changes in regulatory theory: Market-based pricing  

Energy Technology Data Exchange (ETDEWEB)

With the introduction of competition and diversification into retail utility services, rate-making methods are being rethought. Rates that are strictly cost-based may be too slow in responding to changes within the utility industry. And the advent of independent power production as a significant source of energy calls for greater flexibility in pricing of wholesale utility services as well. Various deregulation or reregulation plans have been formulated, including both price cap and price floor proposals. Some regulatory authorities have embraced market-based pricing over cost-based methods as the best solution to pricing problems. This article addresses Federal Energy Regulatory Commission response to market-based rates.

1990-11-08

157

Biological pest control  

Energy Technology Data Exchange (ETDEWEB)

For the purposes of energy forests, biological pest control should be interpreted as any method of using natural organisms or their products for the regulation of herbivores, below the economic threshold. The organisms include the energy forest crop species and natural enemies of pest herbivores. Examples are provided of three-trophic-level interactions, including some on willows and poplars. Bottom-up effects may be particularly strong in juvenile Salicaceae, which are used in energy forest production, because plants are growing vigorously, and many herbivores respond positively. Some major pests on willows and poplars appear to have weak top-down regulation, and they may be influenced most by bottom-up effects such as plant resistance through genetic variation, ontogenetic aging and physiological aging. Balancing the bottom-up and top-down forces in energy forests may be difficult in short-rotation crops, but harvesting may prove to be important as a control ...

1994-01-01

158

An introduction to climate change: a Canadian perspective  

Energy Technology Data Exchange (ETDEWEB)

Current scientific knowledge of climate change and its global impact is summarized in the first four chapters. The earth's natural climate, greenhouse gases, climate prediction models, and impact of a warmer world on natural terrestrial ecosystems, agricultural ecosystems, and coastal regions are discussed. The possible impacts on Canada are described in chapter five, which considers forests, agriculture, water resources, fisheries, coastal zones, transportation, human health and well being, energy production and use, and global security. Chapter six considers ways to respond to climate change. These include enhancing knowledge of climate change, working toward a consensus on the need for action, global political response, the Canadian response, and the role of the individual. 15 refs., 35 figs.

2005-10-15

159

An integrating dosimeter for pulsed radiation  

Science.gov (United States)

A Pulsed Radiation Dosimetry System designed to measure radiation produced by particle accelerators is described. The problems associated with total-dose measurement of irregular shaped pulses of ionizing radiation have been simplified. The system responds to extremely narrow pulses of charged particles or X-rays using a pin diode as the detector. Direct readout of dose in rads (Si) is displayed on a 3-1/2 digit digital panel meter. The system will operate in either the multiple-pulse or single-pulse mode. The multiple-pulse mode would be useful in monitoring or tuning a linear accelerator. In the single-pulse mode the system will automatically display total dose of a transient event in real time and hold that measurement indefinitely or until the next measurement is made. The system features an automatic reset in either mode.

1983-12-01

160

Adjustment of sperm allocation under high risk of sperm competition across taxa: a meta-analysis  

British Library Electronic Table of Contents (United Kingdom)

Abstract Sperm competition theory predicts that under high risk of sperm competition, males will increase the number of sperm that they allocate to a female. This prediction has been supported by some experimental studies but not by others. Here, I conducted a meta-analysis to determine whether the increase in sperm allocation under high risk of sperm competition is a generalized response across taxa. I collected data from 39 studies and 37 species. Across taxa, males under a high risk of sperm competition respond by increasing their sperm allocation (mean effect size-=-0.32). Number of offspring did not explain a significant portion of the variation in effect sizes. A traditional meta-analysis (i.e. without phylogenetic information) described the variation among effect sizes better than a...

2011-01-01

161

A report on the CCNA 2007 professional practice analysis.  

Science.gov (United States)

The purpose of this column is to present the results of the 2007 Professional Practice Analysis (PPA) of the field of nurse anesthesia, conducted by the Council on Certification of Nurse Anesthetists. The PPA used survey and rating scale methodologies to collect data regarding the relative emphasis of various aspects of the nurse anesthesia knowledge domain and competencies. A total of 3,805 survey responses were analyzed using the Rasch rating scale model, which aggregates and transforms ordinal (rating scale) responses into linear measures of relative importance and frequency. Summaries of respondent demographics and educational and professional background are provided, as well as descriptions of how the survey results are used to develop test specifications. The results of this analysis provide evidence for the content outline and test specifications (content percentages) and thus serve as a basis of content validation for the National Certification Examination. ...

2009-06-01

162

A partnership approach to service needs assessment with family caregivers of an aging relative living at home: A qualitative analysis of the experiences of caregivers and practitioners  

British Library Electronic Table of Contents (United Kingdom)

Background: As the global population ages, support for family caregivers who provide the bulk of care to community-dwelling older people is becoming ever more important. However, in many countries, homecare-service practitioners currently do not follow a systematic approach to assessing and responding to caregiver needs. Objectives: The aim of this study was to explore the experiences of caregivers and practitioners who took part in a field test of the Family Caregivers Support Agreement (FCSA) tool, a modified version of the Carers Outcome Agreement Tool (COAT) initially developed as the result of an Anglo-Swedish study. Both the COAT and the FCSA are designed to facilitate partnerships between caregivers and practitioners so that needs assessment and subsequent support services are negot...

2010-01-01

163

1,3 Propanediol and its copolymers: Research, development and industrialization  

British Library Electronic Table of Contents (United Kingdom)

Abstract 1,3 Propanediol (PDO), is now taking the transition from a traditional specialty chemical to a commodity chemical . The market for PDO is growing rapidly as the technology develops. With the advancing PDO production technology, polytrimethylene terephthalate (PTT) as a new type of polyester has been applied in carpet and textile fibers, monofilaments, films, and nonwoven fabrics, and in the engineering thermoplastics area, because PTT has unique properties compared to other polymers such as polyethylene terephthalate (PET) and polybutylene terephthalate (PBT). Responding to the environmental and sustainability factors, one or two step fermentation technology for PDO production has attracted people's attention. A novel flexible process for PDO production by using aerobic fermentati...

2010-01-01

164

Robust consensus clustering for identification of expressed genes linked to malignancy of human colorectal carcinoma  

UK PubMed Central (United Kingdom)

Previous studies have been conducted in gene expression profiling to identify groups of genes that characterize the colorectal carcinoma disease. Despite the success of previous attempts to identify...Full Text Available

165

Multilevel support vector regression analysis to identify condition-specific regulatory networks  

UK PubMed Central (United Kingdom)

Motivation: The identification of gene regulatory modules is an important yet challenging problem in computational biology. While many computational methods have been proposed to identify...Full Text Available

2010-06-01

166

Light duty utility arm startup plan  

Energy Technology Data Exchange (ETDEWEB)

This plan details the methods and procedures necessary to ensure a safe transition in the operation of the Light Duty Utility Arm (LDUA) System. The steps identified here outline the work scope and identify responsibilities to complete startup, and turnover of the LDUA to Characterization Project Operations (CPO).

1998-09-01

167

Large-scale cross-species oncogenomics identifies candidate oncogenes and tumor suppressor genes  

UK PubMed Central (United Kingdom)

While genomic alterations identified in human tumors using techniques such as comparative genomic hybridisation (CGH) may be recurrent, they frequently encompass large regions, in some cases...Full Text Available

2010-02-01

168

Intelligent techniques applied in identifying fraudsters industrial consumers of electricity; Tecnicas inteligentes aplicadas na identificacao de consumidores industriais fraudadores de energia eletrica  

Energy Technology Data Exchange (ETDEWEB)

The development of a computational intelligent tools based on neural network to identify commercial losses or fraud (theft energy), considering information from a database electric utility, is presented.

2009-07-01

169

How and when can one identify hadronic molecules in the baryon spectrum  

Energy Technology Data Exchange (ETDEWEB)

A method to identify hadronic molecules in the particle spectrum is reviewed and the conditions for its applicability discussed. Special emphasis is put on the discussion of molecule candidates in the baryon spectrum. (orig.)

2008-03-15

170

Contingency Space Analysis: An Alternative Method for Identifying Contingent Relations from Observational Data  

UK PubMed Central (United Kingdom)

Descriptive assessment methods have been used in applied settings to identify consequences for problem behavior, thereby aiding in the design of effective treatment programs. Consensus has not been...Full Text Available

2008-01-01

171

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer  

UK PubMed Central (United Kingdom)

Cancers are highly heterogeneous and contain many passenger and driver mutations. To functionally identify tumor suppressor genes relevant to human cancer, we compiled pools of short harpin...Full Text Available

2008-11-28

172

A DNA transposon-based approach to validate oncogenic mutations in the mouse  

UK PubMed Central (United Kingdom)

Large-scale cancer genome projects will soon be able to sequence many cancer genomes to comprehensively identify genetic changes in human cancer. Genome-wide association studies have also identified...Full Text Available

2008-12-16

173

45 CFR 162.404 - Compliance dates of the implementation of the standard unique health identifier for health care...  

Science.gov (United States)

...dates of the implementation of the standard unique health identifier for health care providers. 162.404 Section 162.404 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATIVE DATA...

2010-10-01

174

The DIVAD Archaeological Project  

Science.gov (United States)

... Like other surveys in the Hueco Bolson (Carmichael 1983; Whalen 1977, 1978), the BLM survey identified large concentrations of Pueblo period ...

2011-05-14

175

DIGITAL LIBRARIES: IMPACT ON SCIENCE ... - MUSPIN - NASA  

Science.gov (United States)

digital libraries, which was identified as a national challenge in the Information ... The linkages between the many digital libraries and information services are ...

176

Cartridge Cases  

Science.gov (United States)

... reverse aeb 9 nescesmsy amI identify by block number) Provides procedures for evaluating metal, consumable, and combustible cartridge cases. ...

1980-10-21

177

Aviation Maintenance Safety Articles, January/February 1990  

Science.gov (United States)

... These are abnormal and an indication of NAVAIRINST 13340.3 identifies these laboratories a possible breakdown in the fuel-handling equip- ...

1990-02-01

178

Industrial waste and pollution in Mongolia  

Energy Technology Data Exchange (ETDEWEB)

This paper very briefly outlines hazardous waste management issues, including regulations, in Mongolia. Air, water, and soil pollutants are identified and placed in context with climatic, social, and economic circumstances. The primary need identified is technology for the collection and disposal of solid wastes. Municipal waste problems include rapid urbanization and lack of sanitary landfills. Industrial wastes of concern are identified from the mining and leather industries. 4 refs., 2 tabs.

1996-12-31

179

MRI in the diagnosis of non-compacted ventricular Myocardium (NCVM) compared to echocardiography; MR-Tomographie in der morphologischen Darstellung der isolierten non-compaction des linksventrikulaeren Myokards (NCVM)  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To report the detection of con-compacted ventricular myocardium (NVCM) with MRI compared to echocardiography in 8 patients. Material and methods: Non-compaction of the ventricular myocardium is a congenital disorder characterized by an altered structure of the myocardial wall resulting from an intrauterine arrest in endomyocardial embryogenesis. The morphological findings consist of a prominent meshwork of multiple myocardial trabeculations and deep intertrabecular recesses, communicating with the left ventricular cavity. 8 consecutive patients (mean age 7.3 years) with clinical and echocardiographic signs of NCVM were examined by MRI (1.5 T, Vision, Siemens) in short axis and 2- and 4-chamber views, using T{sub 1}-weighted TSE and Cine-GRE in 6 patients and true FISP sequences in 2 patients. MRI and echocardiography were evaluated for visibility, signs of NCVM and involvement of myocardial wall segments. Thickness was measured for non-compacted and ...

2003-09-01

180

Use of sting-response techniques for simulate diagnostics in human esophagus; Uso de tecnicas estimulo-respuesta para simular diagnosticos en esofago humano  

Energy Technology Data Exchange (ETDEWEB)

In this work a study of simulation of the gamma graphic studies that are carried out in human esophagus in the Dept. of Nuclear Medicine of the 'Celestino Hernandez Robau Hospital of Santa Clara is presented. For the investigation tubular reactors were used and sting-response techniques with radioactive tracer of Technetium 99 metastable to a concentration of 1 mCi and several flows were applied. The distribution curves of residences times were obtained, those that respond to an equation of the type: Y = A + B exp (- exp((x-C)/D)) - ((x-C/D)+1). They were also carried out, optimizations studies of the doses of the radioactive to give to the patients from 1 mCi (that is the one used in studies) up to 0,5 mCi, and the influences on the obtained distributions of residence time were analyzed. It was confirmed the possibility to lower the doses with clear information of the signal. It was also carried out a simulation of the attenuation of the radiations that ...

2003-07-01

181

Teachers' Perception and Perceived Contributions towards the Success of the Universal Basic Education (UBE) Programme  

Science.gov (United States)

Grassroots education is imperative if economic development is to be actualized. Therefore, it becomes necessary to study the primary school teachers' perception of the Universal Basic Education (UBE). This study attempted to find out the primary school teachers' perception of the Universal Basic Education (UBE) programme and their perceived contribution towards the success of the programme. It further examined how favorable perception towards the scheme could be a catalyst in the successful implementation of the UBE. To accomplish this task, two research questions and a hypothesis were raised to guide the study. The opinion of one hundred and eighteen (118) teachers, out of four hundred and forty-seven teachers (447) that constituted the population of the teachers in Esan West Public Primary Schools was obtained. The respondents were randomly selected. The questionnaire was used for data collection. A 1-4 Likert-type scale ranging from Strongly Agreed to Strongly ...

2008-06-01

182

Survey of Radiation Protection Education and Training in Finland in 2003  

Energy Technology Data Exchange (ETDEWEB)

The current state and need for radiation protection training in Finland have been surveyed by the Radiation and Nuclear Safety Authority STUK. The survey sought to determine whether the current requirements for radiation protection training had been met, and to promote radiation protection training. Details of the scope and quality of present radiation protection training were requested from all educational institutes and organizations providing radiation protection training. The survey covered both basic and further training, special training of radiation safety officers, and supplementary training. The questionnaire was sent to 77 educational organization units, 66 per cent of which responded. Radiation workers and radiation safety officers were asked about radiation protection knowledge and needs for additional training. The questionnaire was sent to 880 radiation users and 170 radiation safety officers, 70 per cent of whom responded. The ...

2004-07-01

183

Pathogenesis of trypanosome infections in cattle  

International Nuclear Information System (INIS)

The potential application of radioisotopes are not discussed in this review of trypanosome pathogenesis in cattle. Initially, structural changes in the lymphoid system are characterized by marked proliferation and germinal centre formation, whereas in long-standing infections the lymphoid organs become depleted. These changes appear associated with immunodepression. Anaemia dominates the clinical disease syndrome in bovine trypanosomiasis. It develops with the onset of parasitaemia and is largely haemolytic, resulting from increased red blood cell destruction by phagocytosis. Several factors may be involved in this process including haemolysins produced by the trypanosome, immunological mechanisms, fever, disseminated intravascular coagulation and an expanded and active mononuclear phagocytic system. During this phase of the disease, cattle respond well to chemotherapy. However, in later phases of the disease, when trypanosomes cannot be detected, the anaemia ...

1979-05-11

184

Global positioning automatic vehicle location system  

Energy Technology Data Exchange (ETDEWEB)

Los Alamos National Laboratory (LANL) is a unique facility covering over 43 square miles. The Emergency Management and Response Office (EM&R) is required to respond, provide Incident Command (IC), and coordination for all Laboratory emergencies. This requires IC`s and support staff to respond to the actual scene of the incident. Since the IC is under numerous constraints and stress, the office wanted the capability of locating the EM&R vehicles on an electronic map. An automated vehicle location (AVL) system was required for the additional safety of the emergency response personal. The requirements for the AVL system include total automatic tracking and low cost. After careful consideration, it was determined that the most efficient and cost effective system would be based on packet radio technology as the transmission media. The location is determined by the Department of Defense Global Positioning System (GPS). The system that was ...

1997-03-01

185

Ewing's sarcoma treatment in Scandinavia 1984-1990. Ten-year results of the Scandinavian sarcoma group protocol SSGIV  

International Nuclear Information System (INIS)

A report on the long-term follow up of the first cooperative Scandinavian Sarcoma Group study in Ewing's sarcoma of bone is presented. Fifty-two previously untreated patients entered the study between 1984 and 1990. Half of the tumors were located in the extremities and one quarter in the pelvis. The combined modality treatment consisted of 5 cycles of chemotherapy - including vincristine, methotrexate, doxorubicin, cyclophosphamide, bleomycin and dactinomycin. The first two cycles were followed by local resection or amputation in 35 patients and by radiotherapy alone in 17 patients. When surgery was not performed, was incomplete or yielded poor margins radiotherapy was given at a dose of 40-60 Gy. Local tumor relapses developed in 10 patients and in all but one patient were accompanied by metastatic disease. Five patients had metastasis at diagnosis and distant metastases developed after primary treatment in 27 patients after a median of 14 months. The median follow-up time for the 20 ...

186

Community-based oil spill response in Alaska  

Energy Technology Data Exchange (ETDEWEB)

The Prince William Sound Regional Citizen's Advisory Council and the Cook Inlet Regional Citizen's Advisory Council are independent, non profit organizations formed in 1989 following the Exxon Valdez oil spill to promote the concept of community-based oil spill response (COSR) in their respective regions. COSR involves local citizens in responding to oil spilled in waters they rely upon for income, recreation and subsistence. The 2 advisory councils recently held a Community Oil Spill Response Forum to review the status of existing COSR teams and to share information about past and future COSR-related efforts. The meeting served as an information exchange process about regulatory programs, COSR variations in communities and harbors, training, and personnel issues. Key groups attending the forum were harbor masters, Alaska Department of Environmental Conservation, United States Coast Guard, existing COSR teams, oil response organizations, local ...

2006-07-01

187

Nuclear emergencies and behavior of the people: a challenge  

International Nuclear Information System (INIS)

Full text: The IRSN has been organizing enquiries with the French population about risk and risk perception for a long time. In 2002, a collaboration between the IRSN in France and the SCK.CEN in Belgium has been set-up to simultaneously (November 2002) organise this poll in both countries. In each country, a representative sample of the population (over 1000 participants per country) has been consulted by Computer Aided Personal Interviews of about 30 minutes with the professional help of commercial companies: BVA in France and Research International in Belgium. The enquiry yields a broad spectrum of interesting data; here only the results relevant for the emergency context will be presented. One should be aware that these data were collected in a 'normal' period; important differences in behaviour may occur given a serious crisis. A first finding is that more than half of the respondents are convinced that an accident as severe as the Chernobyl disaster may ...

2003-10-03

188

Technical area status report for chemical/physical treatment. Volume 2, Appendices  

Energy Technology Data Exchange (ETDEWEB)

These Appendices describe various technologies that may be applicable to the Mixed Waste Treatment Plant (MWTP) Chemical/Physical Treatment System (CPTS). These technologies were identified by the CPTS Technical Support Group (TSG) as potentially applicable to a variety of separation, volume reduction, and decontamination requirements. The purpose was to identify all available and developing technologies, and their characteristics, for subsequent evaluation for specific requirements identified for the CPTS. However, the technologies described herein are not necessarily all inclusive, nor are they necessarily all applicable.

1993-08-01

189

Nuclear fuel assembly identification using computer vision  

Science.gov (United States)

This report describes an improved method of remotely identifying irradiated nuclear fuel assemblies. The method uses existing in-cell TV cameras to input an image of the notch-coded top of the fuel assemblies into a computer vision system, which then produces the identifying number for that assembly. This system replaces systems that use either a mechanical mechanism to feel the notches or use human operators to locate notches visually. The system was developed for identifying fuel assemblies from the Fast Flux Test Facility (FFTF) and the Clinch River Breeder Reactor, but could be used for other reactor assembly identification, as appropriate.

1985-11-01

190

MEG studies of human vision: Retinotopic organization of V1  

Energy Technology Data Exchange (ETDEWEB)

A primary goal of noninvasive studies of human vision is to identify and characterize multiple visual areas in the human brain analogous to those identified in studies of nonhuman primates. By combining functional MEG measurements with images of individual anatomy derived from MRI, the authors hope to determine the location and arrangement of multiple visual areas in human cortex and to probe their functional significance. The authors have identified several different visual areas thus far which appear to be topographically organized. This paper focuses on the retinotopic characterization of the primary visual area (V1) in humans.

1993-12-31

191

sUAS Presentation 26June08.ppt  

Science.gov (United States)

Jun 26, 2008 ... NAVAIRINST 13034.1C. ACC/ARC/ NAT IPT/EDT ENGINEERING. OWNER. FLEET. REQUIREMENT. IDENTIFIED. PROGRAM INITIATED ...

192

Timber Compartment Boundary  

Science.gov (United States)

Timber Compartment Boundary This data set identifies the 90 timber compartment boundaries in a 200 square-mile study ... Kawishiwi Ranger Districts, Superior National ...

194

The early phase change Gene in Maize  

UK PubMed Central (United Kingdom)

Recessive mutations of the early phase change (epc) gene in maize affect several aspects of plant development. These mutations were identified initially because of...Full Text Available

2002-01-01

195

The Physical Attractiveness of Electronic Physician Notes  

UK PubMed Central (United Kingdom)

Though notes in electronic medical record systems (EMRs) have advantages, they are often criticized for their unattractive and unprofessional appearance. We sought to identify notes regarded by physicians...Full Text Available

2010-01-01

196

The I3I Model; Identifying Cultural Determinants of Information ...  

Science.gov (United States)

... Information behavior in dynamic group work contexts: Interwoven situational awareness, dense social networks and contested collaboration in ...

2009-06-01

197

The Financial War on Terrorism: Grading US Strategy for ...  

Science.gov (United States)

... that operated in Pakistan, Dubai, and throughout the Middle East ... identifies 'funds' as one of eight major terrorist ... techniques, and procedures (TTP). ...

2006-04-15

198

Survey of non-prescribed use of antibiotics for children in an urban community in Mongolia  

UK PubMed Central (United Kingdom)

AbstractObjectiveTo estimate the prevalence and identify the determinants of non-prescription use of antibiotics for children in Mongolia.MethodsA...Full Text Available

2010-12-01

199

Social, Clinical and Microbiological Differential Characteristics of Tuberculosis among Immigrants in Spain  

UK PubMed Central (United Kingdom)

BackgroundTo identify the differential tuberculosis (TB) characteristics within the immigrant population with respect to natives in Spain.Methodology/Principal...Full Text Available

200

Science and technology for industrial ecology  

Energy Technology Data Exchange (ETDEWEB)

This paper first discusses the challenge offered by natural and anthropogenic systems in all of their complexity and then indicates some areas of research in which specific scientific and technological needs are identifiable.

1996-07-10

201

Role of Orvosi Hetilap in the development of Hungarian gastroenterology  

UK PubMed Central (United Kingdom)

AIM: To analyze the contribution of Orvosi Hetilap (Hungarian Medical Journal) to the field of gastroenterology.METHODS: All issues of the journal between 1857 and 2008 and identified...Full Text Available

2010-05-14

202

Report of the Geostatistical Analysis of High Resolution ...  

Science.gov (United States)

... The variogram analysis of the high resolution imagery has shown that although more spatial scales have been identified than from the SPOT image ...

1998-05-01

203

Plasmid-Determined Copper Resistance in Pseudomonas syringae from Impatiens  

UK PubMed Central (United Kingdom)

A strain of Pseudomonas syringae was recently identified as the cause of a new foliar blight of impatiens. The bacterium was resistant to copper compounds, which are used on a variety...Full Text Available

1990-01-01

204

Physiologic changes during growth and development.  

UK PubMed Central (United Kingdom)

To express growth-related changes in physiologic or other functions in forms usable for kinetic modeling, we are interested in identifying regular relationships that take the form of simple mathematical...Full Text Available

1994-12-01

205

Patient persistence with first-line antiglaucomatous monotherapy  

UK PubMed Central (United Kingdom)

PurposeTo identify the extent of persistence (period of time of continuous therapy with the drug prescribed) of glaucoma patients treated with prostaglandins (latanoprost, bimatoprost,...Full Text Available

2010-01-01

206

Optimization for Vibration Isolation.  

Science.gov (United States)

An almost linear optimization problem of importance in vibration isolation has been identified and algorithms were developed to minimize the forced vibrational response of structural systems. The constraints can be either displacements of accelerations. T...

1983-01-01

207

Mutations in RNA Binding Protein Gene Cause Familial Dilated Cardiomyopathy  

UK PubMed Central (United Kingdom)

ObjectivesWe sought to identify a novel gene for dilated cardiomyopathy (DCM).BackgroundDCM is a heritable, genetically...Full Text Available

2009-09-01

208

Medical Conditions of Nursing Home Admissions  

UK PubMed Central (United Kingdom)

BackgroundAs long-term nursing home care is likely to increase with the aging of the population, identifying chronic medical conditions is of particular interest. Although need factors...Full Text Available

209

Measurement methods for human exposure analysis.  

UK PubMed Central (United Kingdom)

The general methods used to complete measurements of human exposures are identified and illustrations are provided for the cases of indirect and direct methods used for exposure analysis. The application...Full Text Available

1995-04-01

211

Factors Linked to Bacterial Vaginosis in Nonpregnant Women  

UK PubMed Central (United Kingdom)

Objectives. The purposes of this study were to test the hypothesis that vaginal douching is linked to bacterial vaginosis in both symptomatic and asymptomatic women and to identify...Full Text Available

2001-10-01

212

Facilities evaluation report  

Energy Technology Data Exchange (ETDEWEB)

The Buried Waste Integrated Demonstration (BWID) is a program of the Department of Energy (DOE) Office of Technology Development whose mission is to evaluate different new and existing technologies and determine how well they address DOE community waste remediation problems. Twenty-three Technical Task Plans (TTPs) have been identified to support this mission during FY-92; 10 of these have identified some support requirements when demonstrations take place. Section 1 of this report describes the tasks supported by BWID, determines if a technical demonstration is proposed, and if so, identifies the support requirements requested by the TTP Principal Investigators. Section 2 of this report is an evaluation identifying facility characteristics of existing Idaho National Engineering Laboratory (INEL) facilities that may be considered for use in BWID technology demonstration activities.

1992-04-01

213

Coping Strategies of Family Members of Hospitalized Psychiatric Patients  

UK PubMed Central (United Kingdom)

This exploratory research paper investigated the coping strategies of families of hospitalized psychiatric patients and identified their positive and negative coping strategies. In this paper, the coping...Full Text Available

2011-01-01

214

Computer Vision Hardware System for Automating Rough Mills of Furniture Plants  

Science.gov (United States)

... company. To automate this initial cutup requires a computer vision system that can locate and identify surface defects ... ...

215

Characterization of a mycovirus associated with the brown discoloration of edible mushroom, Flammulina velutipes  

UK PubMed Central (United Kingdom)

BackgroundA mycovirus previously identified in brown discolored fruiting bodies of the cultivated mushroom Flammulina velutipes was characterized. We tentatively...Full Text Available

216

Cartridge Cases.  

Science.gov (United States)

This report provides procedures for evaluating metal, consumable, and combustible cartridge cases. It identifies supporting tests, facilities, and equipment required. Subtests include weapon and ammunition preparation, initial inspection, ammunition chara...

1980-01-01

217

Biosynthesis and metabolism of salicylic acid.  

UK PubMed Central (United Kingdom)

Pathways of salicylic acid (SA) biosynthesis and metabolism in tobacco have been recently identified. SA, an endogenous regulator of disease resistance, is a product of phenylpropanoid metabolism formed...Full Text Available

1995-05-09

218

Biogenesis of the Protein Storage Vacuole Crystalloid  

UK PubMed Central (United Kingdom)

We identify new organelles associated with the vacuolar system in plant cells. These organelles are defined biochemically by their internal content of three integral membrane proteins: a chimeric reporter...Full Text Available

2000-08-21

219

Alpha-toxin of Staphylococcus aureus.  

UK PubMed Central (United Kingdom)

Alpha-toxin, the major cytotoxic agent elaborated by Staphylococcus aureus, was the first bacterial exotoxin to be identified as a pore former. The protein is secreted as a single-chain, water-soluble...Full Text Available

1991-12-01

220

49 CFR 130.11 - Communication requirements.  

Science.gov (United States)

...identified as oil when the shipment document accurately describes the material as: aviation fuel, diesel fuel, fuel oil, gasoline, jet fuel, kerosene, motor fuel, or...

2010-10-01

221

Turbocharger for micro-cars; Keijidoshayo turbocharger  

Energy Technology Data Exchange (ETDEWEB)

This paper explains technologies for turbo chargers used in light cars. Light car engine turbo chargers have been given various improvements responding to needs of the market. Since ball bearings have less mechanical loss than sliding bearings, and enhances greatly the turbo efficiency, they are used in some high performance engines of light cars. While the conventional ball bearing has used high hardness bearing steel, the new standard cars started using ceramic ball. The currently used light car gasoline engines are divided into two kinds, serial three-cylinder type and serial four-cylinder type, either having merits and demerits. The new twin entry turbo developed by IHI arranges divided exhaust gas ports above and below to simplify the manifold shape, and realizes smooth flow by twisting the exhaust gas flow path inside the turbine housing. This makes the dynamic pressure of the exhaust gas more effectively utilized, enhancing the boost pressure and torque. ...

2000-05-20

222

Transforming growth factor-b induces nerve growth factor expression in pancreatic stellate cells by activation of the ALK-5 pathway  

British Library Electronic Table of Contents (United Kingdom)

Nerve growth factor (NGF), a survival factor for neurons enforces pain by sensitizing nociceptors. Also in the pancreas, NGF was associated with pain and it can stimulate the proliferation of pancreatic cancer cells. Hepatic stellate cells (HSC) respond to NGF with apoptosis. Transforming growth factor (TGF)-b, one of the strongest pro-fibrogenic activators of pancreatic stellate cells (PSC) induced NGF and its two receptors in an immortalized human cell line (ihPSC) and primary rat PSC (prPSC) as determined by RT-PCR, western blot, and immunofluorescence. In contrast to HSC, PSC expressed both NGF receptors, although p75NTR expression was weak in prPSC. In contrast to ihPSC TGF-b activated both Smad signaling cascades in prPSC. NGF secretion was diminished by the activin-like kinase (ALK)...

2009-01-01

223

The first placebo-controlled trial of a special butterbur root extract for the prevention of migraine: reanalysis of efficacy criteria.  

Science.gov (United States)

This is an independent reanalysis of a randomised, placebo-controlled parallel-group study on the efficacy and tolerability of a special butterbur root extract (Petadolex) for the prophylaxis of migraine. The original protocol and analysis had a number of major shortcomings. In order to follow regulatory requirements, an independent reanalysis of the original data was performed. Following a 4-week baseline phase, 33 patients were randomised to treatment with two capsules 25 mg butterbur twice a day and 27 to placebo. The mean attack frequency per month decreased from 3.4 at baseline to 1.8 after 3 months (p = 0.0024) in the verum group and from 2.9 to 2.6 in the placebo group (n.s.). The responder rate (improvement of migraine frequency > or =50%) was 45% in the verum group and 15% in the placebo group. Butterbur was well tolerated. This small trial indicates that butterbur may be effective in the prophylaxis of migraine. PMID:14752215

2004-01-28

224

Somatostatin receptor scintigraphy might be useful for detecting skeleton abnormalities in patients with multiple myeloma and plasmacytoma  

International Nuclear Information System (INIS)

Somatostatin receptor expression has been demonstrated on a number of plasma cell lines. Therefore, we questioned whether somatostatin receptor scintigraphy (SRS) can be used to demonstrate in vivo multiple myeloma (MM) activity. SRS was performed in newly diagnosed (n = 9) or relapsing (n = 18) MM patients or in patients with localized plasmacytoma (n = 2). The results were compared with radiographic findings. A positive SRS was demonstrated in 44% of the newly diagnosed patients, in 83% of the relapsed patients and in both patients with plasmacytoma. The SRS findings corresponded with radiographic abnormalities in 40% of the patients. However, in relapsed patients 60% demonstrated increased SRS uptake in areas without new radiographic abnormalities. The positive SRS corresponded with histologically proven disease activity and responded upon treatment. Moreover, immunohistochemical staining of MM material demonstrated concordant somatostatin receptor sst3 staining ...

2010-01-01

225

Salivary cortisol assessment in the evaluation of hypothalamic-pituitary-adrenal function  

International Nuclear Information System (INIS)

A simple, short and sensitive direct radio-immunoassay technique for the determination of salivary cortisol concentration was employed to assess saliva as a medium for evaluating cortisol response during endocrine testing in 9 controls and 40 patients. Results in controls suggested that an adequate salivary cortisol response to insulin hypoglycaemia was an increase of 150% above the basal value with a minimum peak of 15 nmol/l. Thirty-three patients were classified as being either good or poor responders to insulin hypoglycaemia on the basis of criteria for plasma cortisol levels. When the defined salivary cortisol response was used for assessment, all 33 patients were correctly categorized into the same response groups. The salivary cortisol response to intramuscular tetracosactin in 3 patients and an intravenous dexamethasone infusion in 4 patients confirmed the value of saliva as an assay medium. These studies show that the salivary cortisol response parallels ...

1984-05-01

226

Safety significance of ATR passive safety response attributes  

International Nuclear Information System (INIS)

The Advanced Test Reactor (ATR) at the Idaho National Engineering Laboratory was designed with some passive safety response attributes which contribute to the safety of the facility. The three passive safety attributes being evaluated in the paper are: 1) In-core and in-vessel natural convection cooling, 2) a passive heat sink capability of the ATR primary coolant system (PCS) for the transfer of decay power from the uninsulated piping to the confinement, and 3) gravity feed of emergency coolant makeup. The safety significance of the ATR passive safety response attributes is that the reactor can passively respond to most transients, given a reactor scram, to provide adequate decay power removal and a significant time for operator action should the normal active heat removal systems and their backup systems both fail. The ATR Interim Level 1 Probabilistic Risk Assessment (PRA) models and results were used to evaluate the significance to ATR fuel damage frequency (or ...

1990-03-01

227

Responses to comments received on the draft final report of the Secretary of Energy Advisory Board Task Force on Radioactive Waste Management  

Energy Technology Data Exchange (ETDEWEB)

The Task Force solicited comments on its Draft Final Report from a variety of sources. Letters were sent to over 400 individuals who had expressed interest in the interest in the Department`s radioactive waste, management programs, a notice was placed in the Federal Register, the morning session of the January 1993 meeting of the full Secretary of Energy Advisory Board was given over to discussion of the draft, and Task Force members and staff presented the effort at several professional meetings. Altogether 32 written comments were received. They are reproduced here, followed in each case by the Task Force`s response to specific suggestions made to improve the draft. (The panel did not respond to comments that simply reflected policy preferences or that praised the group`s effort.) With one exception, those specific suggestions are highlighted and given a letter designation from {open_quotes}A{close_quotes} to {open_quotes}Z{close_quotes}. The Task Force`s ...

1994-10-01

228

Report of the US Nuclear Regulatory Commission Piping Review Committee. Volume 3. Evaluation of potential for pipe breaks  

Energy Technology Data Exchange (ETDEWEB)

The Executive Director for Operations (EDO) in establishing the Piping Review Committee concurred in its overall scope that included an evaluation of the potential for pipe breaks. The Pipe Break Task Group has responded to this directive. This report summarizes a review of regulatory documents and contains the Task Group's recommendations for application of the leak-before-break (LBB) approach to the NRC licensing process. The LBB approach means the application of fracture mechanics technology to demonstrate that high energy fluid piping is very unlikely to experience double-ended ruptures or their equivalent as longitudinal or diagonal splits. The Task Group's reommendations and discussion are founded on current and ongoing NRC staff actions as presented in Section 3.0 of this report. Additional more detailed comments and discussion are presented in Section 5.0 and in Appendices A and B. The obvious issues are the reexamination of the large pipe ...

1984-11-01

229

Rapid Responding Palladium-Silver Surface Modified Microsensor for Hydrogen  

Science.gov (United States)

Most palladium thin film based hydrogen gas sensors have response and recovery times that are too long to make them useful in vehicular and stationary gas leak detection applications. In contrast, a palladium-silver thin film based microcantilever (MC) hydrogen gas microsensor is reported herein with near ideal response characteristics for use in these hydrogen economy related applications. Specifically, 3-10 second response and recovery times have been measured for these sensors in contrast to previous sensor response measurements of several to tens of minutes using Pd thin film and MC based sensing techniques. The much reduced response times observed in the present study are attributed to a wet chemical Pd-Ag thin film deposition technique and a gas conditioning protocol that produces a highly nanostructured, porous film that rapidly adsorbs and desorbs H2, allowing rapid equilibration with the H2 concentration in the surrounding air. The wet chemical process and gas phase ...

2010-01-01

230

Prognosis of non-small cell lung cancer with brain metastases and the clinical role of cranial irradiation  

Energy Technology Data Exchange (ETDEWEB)

Prognosis of 95 consecutive patients with non-small cell lung cancer with brain metastases were evaluated. Three factors, therapy for brain metastases, general performance status (PS) and distant metastases to other organs had significant impact on survival. Among these 3 factors, PS was independent from the other 2 factors. Significant correlation was present, however, between therapy and other organ metastases, and few patients with brain and other distant metastases received aggressive treatment for brain metastases. Cranial irradiation had significant impact on survival even in those patients with brain and other distant metastases. Cranial irradiation also reduced death from brain metastases in responders. Our results indicate that there are several subgroups with different prognosis in patients with non-small cell lung cancer with brain metastases, therefore the most beneficial treatment modality should be selected for each group of patients. (author).

1990-10-01

231

Operational performance of generator condition monitors; Comparison of heated and unheated ion chambers  

Energy Technology Data Exchange (ETDEWEB)

This paper reports on the generator condition monitor (GCM) developed in an attempt to detect overheating inside large turbine generators. As part of a broader study on rotating machinery diagnostics, generator condition monitors were evaluated under field conditions in a 550 MW turbogenerator. Small 100 W resistors coated with insulating paints and varnishes were mounted inside the generator to simulate insulation overheating. The GCM responded very rapidly to an overheating event, typically within two minutes, even for hot spots as small s 10 cm{sup 2}. Similarly the aerosols produced on overheating were found extremely short lived, decaying within two to three minutes after overheating was discontinued. Use of heated ion chambers was found to desensitize the GCM regardless of the nature of the overheated insulation and in some cases would altogether prevent the GCM from reaching the 50% pre-set alarm level commonly used on GCMs.

1990-06-01

232

Monitoring challenges and innovative ideas  

Energy Technology Data Exchange (ETDEWEB)

Monitoring programs are difficult to design even when they focus on specific problems. Ecosystems are complex, and it is often impossible to predetermine what aspects of system structure or dynamics will respond to a specific insult. It is equally difficult to interpret whether a response is a stabilizing compensatory mechanism or a real loss of capacity to maintain the ecosystem. The problems are compounded in a broad monitoring program designed to assess ecosystem health'' at regional and continental scales. It is challenging in the extreme to monitor ecosystem response, at any scale, to past insults as well as an unknown future array of impacts. The present paper will examine some of the fundamental issues and challenges raised by large-scale monitoring efforts. The challenges will serve as a framework and as an excuse to discuss several important topics in more detail. Following the discussion of challenges, we suggest some basic innovations ...

1990-01-01

233

Middle school integrated science, mathematics and technology curriculum. Final report, September 30, 1991--December 31, 1993  

Energy Technology Data Exchange (ETDEWEB)

The Project ``Middle School Integrated Science, Mathematics and Technology Curriculum`` had two goals: (1) to survey the literature of energy education; and (2) to develop a theme for a possible integrated middle school energy based curriculum. We aimed to respond to the challenge of developing thematic integrated curricula as advocated by the NSTA, AAAS and other organizations analyzing the future of American science and mathematics education. The survey of middle school energy curriculum materials has been completed. A list of the resources surveyed are included in this report. Though many energy based curriculum materials have been produced, none of them appears to be broadly disseminated throughout the country. Some energy based curriculum materials are far less well developed than others. We found that an integrated set of modular materials concerning the energy based theme of light and optics does not now exist. If they were developed, they could be broadly ...

1994-03-01

234

Male mammals respond to a risk of sperm competition conveyed by odours of conspecific males  

Science.gov (United States)

Sperm competition occurs when a female copulates with two or more males and the sperm of those males compete within the female's reproductive tract to fertilize her eggs. The frequent occurrence of sperm competition has forced males of many species to develop different strategies to overcome the sperm of competing males. A prevalent strategy is for males to increase their sperm investment (total number of sperm allocated by a male to a particular female) after detecting a risk of sperm competition. It has been shown that the proportion of sperm that one male contributes to the sperm pool of a female is correlated with the proportion of offspring sired by that male. Therefore, by increasing his sperm investment a male may bias a potential sperm competition in his favour. Here we show that male meadow voles, Microtus pennsylvanicus, increase their sperm investment when they mate in the presence of another male's odours. Such an increase in sperm investment does not occur by augmenting ...

2004-09-01

235

Long-term effects of prenatal x-ray of human females: reproductive experience  

Energy Technology Data Exchange (ETDEWEB)

A cohort of singleton black human females exposed to diagnostic x-ray in utero and controls matched by parity, hospital of birth and birthdate have been followed to ages 25 to 30 years in Baltimore, Maryland. The search for possible effects of prenatal irradiation has focused on health, growth, development, and reproductive experience of exposed and control women. This paper reports findings related to reproductive experience. From an original data set of 1458 matched exposed-control pairs of women, questionnaire responses were received from 1109 exposed and 1124 control women including 852 each from pairs in which both the exposed and control woman responded. After careful search for alternative explanations of the findings, the authors concluded that females exposed in utero to low doses of x-ray (probably 1 to 5 rads) had significant increases in their rates of early onset of menses, births at age 15 years or less, numbers of living children, stillbirths, and ...

1981-09-01

236

Lessons from the private sector on performance-based management  

Energy Technology Data Exchange (ETDEWEB)

Implementation of the Government Performance and Results Act of 1993 (GPRA) has provided a unique challenge for Federal Agencies, such as the Department of Energy (DOE) Office of Waste Management (OWM). While performance measurement, as required by GPRA, is new to Federal Agencies, private industry has applied it at all organizational levels to better manage their operations for some time. There has been significant discussion about how the private sector uses performance measures, but there have been very few empirical studies systematically examining their use. To gather information on comparable private industry practices, waste management industry firms were surveyed through questionnaires and follow-on interviews. Questionnaires were sent to 75 waste management firms throughout the United States and Canada. Twenty-four percent of the firms responded to the questionnaire and participated in the follow-on interviews. The questionnaires were typically completed ...

1996-03-01

237

Intra-day and regime-switching dynamics in electricity price formation  

Energy Technology Data Exchange (ETDEWEB)

This paper analyses the complex, non-linear effects of spot price drivers in wholesale electricity markets: their intra-day dynamics and transient irregularities. The context is the UK market, after the reforms introduced in March 2001, analysed with an original set of price drivers reflecting economic, technical, strategic, risk, behavioural and market design effects. Models are estimated separately as daily time-series of the 48 half-hourly trading periods. All coefficients exhibit substantial intra-day variation, relating to the heterogeneity of operating plants and market design aspects. This reveals a market responding to economic fundamentals and plant operating properties, with learning and emergent financial characteristics, as well as some strategic manipulation of capacity, most effectively exercised by the more flexible plants. Using regime-switching parameters, the effects of capacity margin and inter-day capacity adjustment are elucidated, suggesting ...

2008-07-15

238

International technical working group cooperation to counter illicit nuclear trafficking  

International Nuclear Information System (INIS)

The Nuclear Smuggling International Technical Working Group (ITWG) is an international group of nuclear forensic experts that cooperate to deter the illicit trafficking of nuclear materials. The objective of the ITWG is to provide a common approach and effective technical solutions to governments who request assistance in nuclear forensics. The ITWG was chartered in 1996 and since that time more than 28 nations and organizations have participated in 9 international meetings and 2 analytical round-robin trials. Soon after its founding the ITWG adopted a general framework to guide nuclear forensics investigations that includes recommendations for nuclear crime scene security and analysis, the best application of radioanalytical methods, the conduct of traditional forensic analysis of contaminated materials, and effective data analysis to interpret the history of seized nuclear materials. This approach has been adopted by many nations as they respond to incidents of ...

2004-10-01

239

Hyaluronic acid production by irradiated human synovial fibroblasts  

International Nuclear Information System (INIS)

Radioactive particles as well as x irradiation from an external source has been used in the treatment of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. In order to clarify effects of ionizing irradiation on synovial cells, radioactive gold ("1"9"8Au) and yttrium ("9"0Y) were added to fibroblast cultures derived from human synovial membranes. Other cultures were irradiated by a Picker x-ray machine. Fibroblast growth and hyaluronic acid production were measured. Radioactive gold and yttrium particles induced a significant increase of hyaluronic acid synthesis rate (pg/cell/day) and inhibited fibroblast growth. Fibroblasts continued to overproduce hyaluronic acid and to show growth inhibition 3 weeks after irradiation with radioactive gold. Hydrocortisone inhibited hyaluronic acid overproduction induced by radioactive gold. Overproduction of hyaluronic acid induced by the x-ray machine was inhibited by hydrocortisone, actinomycin-D, and cycloheximide. Fibroblasts ...

1977-01-01

240

Historical on the Norm Related to the CO{sub 2} Emission Integrated in the Protocol of Kyoto; Historico sobre la Normativa Relacionada con las Emisiones de CO{sub 2} Integrado en el Protocolo de Kyoto  

Energy Technology Data Exchange (ETDEWEB)

The United Nations Framework Convention on Climate Change (UNFCCC) was approved in 1992 to respond to the worl-wide concern about the warming of the planet. The primary target was the stabilization of the concentration of greenhouse gases in the atmosphere, in an attempt to reduce to the minimum the degradation of the environment caused by humans. By virtue of the Convention, the Parts2 are committed to reach their objectives in the reduction of the emissions. A Conference of the Parts was stablished to promote the effective application of the Convention. The third Conference of the Parts, celebrated in Kyoto (Japan, 1997) approved, by consensus, the denominated Kyoto Protocol, in which 39 developed countries and countries with economies in transition were committed to reduce their emissions of greenhouse gases between years 2008 and 2012 in a 5.2 global percent with respect to the 1990 levels. Three {sup f}lexibility mechanisms{sup w}ere stablished to help the ...

2006-07-01

241

HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY  

Energy Technology Data Exchange (ETDEWEB)

FIU-HCET participated in an ICT meeting at Mound during the second week of December and presented a brief videotape of the testing of the Robotic Climber technology. During this meeting, FIU-HCET proposed the TechXtract technology for possible testing at Mound and agreed to develop a five-page proposal for review by team members. FIU-HCET provided assistance to Bartlett Inc. and General Lasertronics Corporation in developing a proposal for a Program Opportunity Notice (PON). The proposal was submitted by these companies on January 5, 1999. The search for new equipment dismantlement technologies is continuing. The following vendors have responded to requests for demonstration: LUMONICS, Laser Solutions technology; CRYO-BEAM, Cryogenic cutting technology; Waterjet Technology Association, Waterjet Cutting technology; and DIAJET, Waterjet Cutting technology. Based on the tasks done in FY98, FIU-HCET is working closely with Numatec Hanford Corporation (NHC) and Pacific ...

1999-01-31

242

Graduate Quantum Mechanics Reform  

CERN Document Server

We address four main areas in which graduate quantum mechanics education in the U.S. can be improved: course content; textbook; teaching methods; and assessment tools. We report on a three year longitudinal study at the Colorado School of Mines using innovations in all four of these areas. In particular, we have modified the content of the course to reflect progress in the field in the last 50 years, use modern textbooks that include such content, incorporate a variety of teaching techniques based on physics education research, and used a variety of assessment tools to study the effectiveness of these reforms. We present a new assessment tool, the Graduate Quantum Mechanics Conceptual Survey, and further testing of a previously developed assessment tool, the Quantum Mechanics Conceptual Survey (QMCS). We find that graduate students respond well to research-based techniques that have previously been tested mainly in introductory courses, and that they learn a great ...

2008-01-01

243

From Unconscious to Conscious Inclusion: Meeting Special Education Needs in West China  

Science.gov (United States)

The authors map the route undertaken by the Project Management Office of the Gansu Basic Education Project (GBEP) in Gansu Province, China, in instituting measures to ensure good learning opportunities for children with special educational needs within the four poor counties benefiting from this DFID supported project. The main purpose of GBEP has been to increase enrolment and retention in these poor, minority areas so as to achieve universal basic education. As general enrolment increased so did that of pupils with special needs, the educational needs of which the schools began responding to in an unconscious way. However, at the start there was little understanding at the classroom and management levels of how to ensure access to learning as well as access to school. The authors map out the road to change and the methods undertaken to change practice at various management and classroom levels so as to enable schools to provide more adequately for these children. ...

2007-08-01

244

Finite element analysis of stresses associated with transformations in magnesia partially stabilized zirconia  

Energy Technology Data Exchange (ETDEWEB)

Anisotropy finite element analysis was performed to study stresses associated with the tetragonal precipitates and the tetragonal to monoclinic transformation in MgO partially stabilized zirconia. Stresses were assumed to be caused by the lattice misfits between the product phase and the parent phase. In the finite element calculations, the tetragonal and monoclinic precipitates were assumed to be lenticular in shape, and the anisotropic elastic constants of the cubic, tetragonal and monoclinic phases were considered. The purpose of this paper is to obtain some knowledge about how stresses respond when the microstructure is changed, and how stress fields affect microstructure development. The finite element results show that increasing a{sub t}/a{sub c} and decreasing c{sub t}/a{sub c} can create a favorable stress field to reduce the growth rate of tetragonal precipitates during the heat treatment. Stresses associated with the single tetragonal precipitate in an ...

1999-11-30

245

Fat phobia: measuring, understanding, and changing anti-fat attitudes.  

Science.gov (United States)

We examined fat phobia, defined as a pathological fear of fatness, by constructing the Fat Phobia Scale, determining its reliability and validity, examining correlates of fat phobia, and using a treatment approach designed to decrease fat phobia. Study 1 describes the development of the Fat Phobia Scale, a 50-item, modified 5-point semantic differential scale. Subjects (974 females and 117 males) completed the scale; factor analysis yielded six factors. Respondents who are average weight, female, younger, have more than a high school education, or are nonmedical professionals are more likely to have fat phobic attitudes. Study 2 examines fat phobic attitudes of women (N = 40) who had negative feelings about their bodies. Subjects completed the Fat Phobia Scale before and after a treatment approach designed to reduce their feelings of responsibility for fatness. Total scores on the Fat Phobia Scale and scores on all six factors decreased significantly, indicating a ...

1993-12-01

246

Factors affecting actions of ethanol on GABA-activated chloride channels  

International Nuclear Information System (INIS)

Effects of ethanol in vitro on membrane vesicles were evaluated by monitoring "3"6Cl"- influx. Different assay parameters were tested to determine increased or decreased action of ethanol on GABA-activated chloride channels. The ability of 30 mM ethanol to augment "3"6Cl"- flux was seen at 0 degree C, in the absence of GABA, and at 34 degree C in the presence of GABA, using two different assay procedures. Picrotoxin blocked the direct effects of ethanol suggesting GABA_a involvement. Endogenous GABA in the medium surrounding the microsacs was assayed at different temperatures both in the presence and absence of GABA and ethanol. The direct effect of ethanol did not appear to involve the action of endogenous GABA. In addition to temperature effects on the assay, time of membrane storage also influenced ethanol action. Microsacs stored on ice for 2 hours or more lost their ability to respond to ethanol but not to GABA, pentobarbital or flunitrazepam. When these drugs ...

247

Exploring research of factors affecting public acceptance of nuclear energy. Result of a survey at Suginami ward, Tokyo  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this research is to clarify how psychological factor's impact on public acceptance of nuclear energy varies with people's degree of knowledge. For this purpose, we carried out questionnaire survey about nuclear energy at Suginami ward, Tokyo. After collecting data, we applied factor analysis to the data, and found 4 factors: Trust in the Authorities, Superiority of Nuclear Power Generation, Benefit for Nuclear Power Plants' Siting Areas, and Risk Perception about Nuclear Technology. In addition, using multiple regression analysis, we evaluated the impact of the 4 factors on 2 issues: the decision for or against nuclear policy and the reaction to nuclear power plant siting. Consequently, we found the change of impact of all 4 factors on the 2 issues. Especially, the impact of the 4 factors to the reaction to nuclear power plant siting was drastically changed by respondent's degree of knowledge. (author)

2003-03-01

248

Exploring research of factors affecting public acceptance of nuclear energy. Result of a survey at Suginami ward, Tokyo  

International Nuclear Information System (INIS)

The purpose of this research is to clarify how psychological factor's impact on public acceptance of nuclear energy varies with people's degree of knowledge. For this purpose, we carried out questionnaire survey about nuclear energy at Suginami ward, Tokyo. After collecting data, we applied factor analysis to the data, and found 4 factors: Trust in the Authorities, Superiority of Nuclear Power Generation, Benefit for Nuclear Power Plants' Siting Areas, and Risk Perception about Nuclear Technology. In addition, using multiple regression analysis, we evaluated the impact of the 4 factors on 2 issues: the decision for or against nuclear policy and the reaction to nuclear power plant siting. Consequently, we found the change of impact of all 4 factors on the 2 issues. Especially, the impact of the 4 factors to the reaction to nuclear power plant siting was drastically changed by respondent's degree of knowledge. (author)

2003-03-01

249

Expert overseer for mass spectrometer system  

Energy Technology Data Exchange (ETDEWEB)

This patent describes an expert overseer for the operation and real-time management of a mass spectrometer and associated laboratory equipment. The overseer is a computer-based expert diagnostic system implemented on a computer separate from the dedicated computer used to control the mass spectrometer and produce the analysis results. An interface links the overseer to components of the mass spectrometer, components of the laboratory support system, and the dedicated control computer. Periodically, the overseer polls these devices and as well as itself. These data are fed into an expert portion of the system for real-time evaluation. A knowledge base used for the evaluation includes both heuristic rules and precise operation parameters. The overseer also compares current readings to a long-term database to detect any developing trends using a combination of statistical and heuristic rules to evaluate the results. The overseer has the capability to alert lab personnel whenever ...

1991-06-18

250

Expert overseer for mass spectrometer system  

International Nuclear Information System (INIS)

This patent describes an expert overseer for the operation and real-time management of a mass spectrometer and associated laboratory equipment. The overseer is a computer-based expert diagnostic system implemented on a computer separate from the dedicated computer used to control the mass spectrometer and produce the analysis results. An interface links the overseer to components of the mass spectrometer, components of the laboratory support system, and the dedicated control computer. Periodically, the overseer polls these devices and as well as itself. These data are fed into an expert portion of the system for real-time evaluation. A knowledge base used for the evaluation includes both heuristic rules and precise operation parameters. The overseer also compares current readings to a long-term database to detect any developing trends using a combination of statistical and heuristic rules to evaluate the results. The overseer has the capability to alert lab personnel whenever ...

1989-04-04

251

Evaluation of heavy-metal ion toxicity in fish cells using a combined stress protein and cytotoxicity assay  

Energy Technology Data Exchange (ETDEWEB)

All organisms, from bacteria and yeast to humans, respond to physical and chemical stressors by increasing the synthesis of a small group of cellular stress proteins.'' The authors have developed a simple in vitro system for quickly screening environmentally relevant stressors to detect stress-induced proteins that are good candidates for biomarkers. Polyacrylamide gel electrophoresis was used to detect stressor-induced, concentration-dependent changes in cellular stress protein levels in two fish cell culture systems, whereas simultaneous in vitro neutral red uptake cytotoxicity assays measured the stressors effect on cellular physiology. There was a direct concentration-dependent relationship between sublethal cytotoxic effects and the increases in stress protein levels. Increases of 50 to 200% were detected in stress proteins from desert topminnow, Poeciliopsis lucida, hepatoma-derived cell cultures exposed to cadmium or copper. Three proteins ...

1994-08-01

252

Estimates of the width of the wetting zone along a fracture subjected to an episodic infiltration event in variably saturated, densely welded tuff  

Energy Technology Data Exchange (ETDEWEB)

A central issue to be addressed within the Nevada Nuclear Waste Storage Investigations (NNWSI) is the role which fractures will play as the variably saturated, fractured rock mass surrounding the waste package responds to heating, cooling, and episodic infiltration events. Understanding the role of fractures during such events will, in part, depend on our ability to make geophysical measurements of perturbations in the moisture distribution in the vicinity of fractures. In this study we first examine the details of the perturbation in the moisture distribution in and around a fracture subjected to an episodic infiltration event, and then integrate that behavior over the scale at which moisture measurements are likely to be made during the Engineered Barrier Design Test of the NNWSI project. To model this system we use the TOUGH hydrothermal code and fracture and matrix properties considered relevant to the welded ash flow tuff found in the Topopah Spring member at ...

1988-05-31

253

Epigenomic disruption: the effects of early developmental exposures.  

Science.gov (United States)

Through DNA methylation, histone modifications, and small regulatory RNAs the epigenome systematically controls gene expression during development, both in utero and throughout life. The epigenome is also a very reactive system; its labile nature allows it to sense and respond to environmental perturbations to ensure survival during fetal growth. This pliability can lead to aberrant epigenetic modifications that persist into later life and induce numerous disease states. Endocrine-disrupting compounds (EDCs) are ubiquitous chemicals that interfere with growth and development. Several EDCs also interfere with epigenetic programming. The investigation of the epigenotoxic effects of bisphenol A (BPA), an EDC used in the production of plastics and resins, has further raised concern over the impact of EDCs on the epigenome. Using the Agouti viable yellow (A(vy)) mouse model, dietary BPA exposure was shown to hypomethylate both the A(vy) and the Cabp(IAP) metastable ...

2010-10-01

254

Direct electrochemistry of catalase at amine-functionalized graphene/gold nanoparticles composite film for hydrogen peroxide sensor  

International Nuclear Information System (INIS)

Direct electrochemistry and electrocatalysis of catalase (Cat) was studied based on a nano-composite film consisting of amine functionalized graphene and gold nanoparticles (AuNPs) modified glassy carbon electrode. Graphene was synthesized chemically by Hummers and Offeman method and then was functionalized with amino groups via chemical modification of carboxyl groups introduced on the graphene surface. The nano-composite film showed an obvious promotion of the direct electron transfer between Cat and the underlying electrode, which attributed to the synergistic effect of graphene-NH2 and AuNPs. The resultant bioelectrode retained its biocatalytic activity and offered fast and sensitive H2O2 quantification. Under the optimized experimental conditions, hydrogen peroxide was detected in the concentration range from 0.3 to 600 ?M with a detection limit of 50 nM at S/N = 3. The biosensor exhibited some advantages, such as short time respond (2 s), high sensitivity ...

2011-02-28

255

Dialysis and contrast media  

Energy Technology Data Exchange (ETDEWEB)

In a previous survey we revealed uncertainty among responders about (a) whether or not to perform hemodialysis in patients with severely reduced renal function who had received contrast medium; and (b) when to perform hemodialysis in patients on regular treatment with hemodialysis or continuous ambulatory dialysis who received contrast medium. Therefore, the Contrast Media Safety Committee of The European Society of Urogenital Radiology decided to review the literature and to issue guidelines. The committee performed a Medline search. Based on this, a report and guidelines were prepared. The report was discussed at the Ninth European Symposium on Urogenital Radiology in Genoa, Italy. Hemodialysis and peritoneal dialysis safely remove both iodinated and gadolinium-based contrast media. The effectiveness of hemodialysis depends on many factors including blood and dialysate flow rate, permeability of dialysis membrane, duration of hemodialysis and molecular size, ...

2002-12-01

256

Development, dimensions, reliability and validity of the novel Manchester COPD fatigue scale  

DEFF Research Database (Denmark)

INTRODUCTION: Fatigue is a prominent symptom in chronic obstructive pulmonary disease (COPD) and it has distinctive features; however, there is a need for a robust scale to measure fatigue in COPD. METHODS: At baseline, 122 patients with COPD (forced expiratory volume in 1 s (FEV(1)) 52%, women 38%, mean age 66 years) completed a pilot fatigue scale covering a pool of 57 items and underwent a range of tests, including indicators of mood and a short general fatigue questionnaire. All patients responded to the 57-item scale and it was readministered to a subset of 30 patients. The pilot scale was first subjected to constructive validated shortening steps and then to a principal components analysis. RESULTS: The Manchester COPD fatigue scale (MCFS) consists of 27 items, loading into three dimensions: physical, cognitive and psychosocial fatigue. Internal consistency (Cronbach's alpha = 0.97) and test-retest repeatability (r = 0.97, por=16 scores in the Center for ...

2009-01-01

257

Development of the Cooper-Bessemer CleanBurn gas-diesel (dual-fuel) engine  

Energy Technology Data Exchange (ETDEWEB)

NO[sub x] emission legislation requirements for large-bore internal combustion engines have required engine manufacturers to continue to develop and improve techniques for exhaust emission reduction. This paper describes the development of the Cooper-Bessemer Clean Burn gas-diesel (dual-fuel) engine that results in NO[sub x] reductions of up to 92 percent as compared with an uncontrolled gas-diesel engine. Historically, the gas-diesel and diesel engine combustion systems have not responded to similar techniques of NO[sub x] reduction that have been successful on straight spark-ignited natural gas burning engines. NO[sub x] levels of a nominal 1.0 g/BHP-h, equal to the spark-ignited natural gas fueled engine, have been achieved for the gas-diesel and are described. In addition, the higher opacity exhaust plume characteristic of gas-diesel combustion is significantly reduced or eliminated. This achievement is considered to be a major breakthrough, and the concept can ...

1992-07-01

258

Developing, financing and managing merchant (independent) power plants  

Energy Technology Data Exchange (ETDEWEB)

Deregulation and restructuring changes in the electric power industry have provided opportunities to build new power plants. These power plants, however, will not enjoy long-term power purchase agreements with the utilities they serve, but will have to respond to the market. This is where the term `merchant plant` originates. Calpine Corp. presented its reasons for believing that now is the best time to be building new merchant plants based on modern natural gas-fired, combined-cycle power plants. Among those reasons are: (1) construction of new nuclear power plants has been rejected by people on both sides of the border, (2) attempts to promote alternative energy sources such as solar, wind and biomass have not added significant generation capacity and are not likely to do so in the near future because of their high cost, and (3) coal-fired plants are also facing environmental challenges. For all these reasons, modern natural gas-fired, combined-cycle power plants ...

1998-08-01

259

Departure from ICRP-60 in Canadian radiation protection regulations  

International Nuclear Information System (INIS)

The Atomic Energy Control Board (AECB), Canada's nuclear regulatory authority, is preparing new regulations based on ICRP-60. The proposed regulations have some features which are different from ICRP-60, e.g., the limit for pregnant workers was set at a higher level than that proposed in ICRP-60. The AECB, through its consultative process, received many responses from female staff in nuclear medicine. The concern was that it would be very difficult to prove compliance with such low doses, particularly for internal doses. There was an additional concern that hospital administrators would respond to the reduction of the current pregnant worker limit from 10 mSv to the ICRP-60 recommended value of 2 mSv by discriminating against hiring women. A new proposal for the dose limit for pregnant workers has been made which will limit the dose to the mother by means of a combining formula that will take both external and internal doses into account. (author).

260

Conocimiento de Transmision de SIDA y Percepcion Hacia los Ninos con SIDA en el Salon de Clases de los Maestros de Educacion Especial (Knowledge of AIDS Transmission and Special Education Teachers' Attitudes towards Children with AIDS in the Classroom).  

Science.gov (United States)

This Spanish-language master's thesis presents a study which measured special education teachers' knowledge of AIDS (Acquired Immune Deficiency Syndrome) virus transmission and their attitudes toward children with AIDS in schools. Attitudes were then related to social variables such as sex, teacher's age, and knowing someone with AIDS. A survey of 101 Oswego County, New York, special education teachers found that 52 percent had a moderate knowledge about AIDS transmission, and 48 percent of respondents had a positive perception of children with AIDS. Findings also indicated that teachers had received effective training and information about AIDS; teachers seemed to feel insecure about applying that knowledge to particular situations of possible risk; knowing people with AIDS provoked negative or inadequate perceptions of that population; and age, sex, and teaching experience were not related to teachers' perceptions or AIDS knowledge. Several recommendations are ...

1993-12-01

261

Coastal flow in the northwest Gulf of Alaska: The Kenai Current  

Energy Technology Data Exchange (ETDEWEB)

Recent data from the northwest Gulf of Alaska reveal a coastal current which flows westward along the Kenai Peninsula (mainly within 30 km of shore), enters Shelifof Strait, and exits to the southwest of Kodiak Island. This flow, which we call the Kenai Current, has a large seasonal variation in baroclinic transport and maximum surface speed; transport is typically about 0.3 x 10/sup 6/ m/sup 3//s but exceeds 1.0 x 10/sup 6/ m/sup 3//s in fall, with concurrent speed increases from 15--30 cm/s to over 100 cm/s. The coastal flow is clearly distinct from the offshore Alaskan Stream; its seasonal signal is mainly related to a cross-shelf pressure gradient, which responds to an annual hydrological cycle. Current records from Shelikof Srait substantiante the presence of an annual signal and indicate that wind forcing has maximum effect from December through February, but it does not appear to augment flow at other times.

1980-11-20

262

Bioscavenger for protection from toxicity of organophosphorus compounds.  

Science.gov (United States)

Current antidotal regimens for organophosphorus compound (OP) poisoning consist of a combination of pretreatment with a spontaneously reactivating AChE inhibitor such as pyridostigmine bromide, and postexposure therapy with anticholinergic drugs such as atropine sulfate and oximes such as 2-PAM chloride (Gray, 1984). Although these antidotal regimens are effective in preventing lethality of animals from OP poisoning, they do not prevent postexposure incapacitation, convulsions, performance deficits, or, in many cases, permanent brain damage (Dunn and Sidell, 1989). These problems stimulated the development of enzyme bioscavengers as a pretreatment to sequester highly toxic OPs before they reach their physiological targets. Several studies over the last two decades have demonstrated that exogenously administered human serum butyrylcholinesterase (Hu BChE) can be used successfully as a safe, efficacious, and single prophylactic treatment to counteract the toxicity of OPs. It also has ...

2006-01-01

263

Behavioral effects of microwaves  

Energy Technology Data Exchange (ETDEWEB)

Microwaves can produce sensations of warmth and sound in humans. In other species, they also can serve as cues, they may be avoided, and they can disrupt ongoing behavior. These actions appear to be due to heat produced by energy absorption. The rate of absorption depends on the microwave parameters and the electrical and geometric properties of the subject. We therefore, cannot predict the human response to microwaves based on data from other animals without appropriate scaling considerations. At low levels of exposure, microwaves can produce changes in behavior without large, or even measureable, changes in body temperature. Thermoregulatory behavior may respond to those low levels of heat, and thereby affect other behavior occurring concurrently. There are no data that demonstrate that behavioral effects of microwaves depend on any mechanism other than reactions to heat. Our interpretation of whether a reported behavioral effect indicates that microwaves may be ...

1980-01-01

264

BEATRIX-II: In situ tritium test  

Energy Technology Data Exchange (ETDEWEB)

The BEATRIX-II irradiation experiment is an in-situ tritium release experiment being carried out in the Fast Flux Test Facility (FFTF) reactor to evaluate the tritium release characteristics of fusion solid breeder materials. A sophisticated tritium gas handling system has been developed to continuously monitor the tritium recovery from the specimens and facilitate tritium removal from the experiment's sweep gas flow stream. The in-situ recovery experiment accommodates two different in-reactor specimen canisters with individual gas streams and temperature monitoring/control. Ionization chambers have been specifically designed to respond to the rapid changes in the tritium release rate at the anticipated tritium concentrations. Two ceramic electrolysis cells have proved effective in reducing the moisture in the gas streams to hydrogen/tritium. A tritium getter system, capable of reducing the tritium level by a factor greater than 4000, is used to reduce the ...

1990-01-01

265

Assimilation and Segregation of Imperial Subjects: "Educating" the Colonised during the 1910-1945 Japanese Colonial Rule of Korea  

Science.gov (United States)

This study looks at how education policies in colonial Korea changed over time in order to accommodate the needs of the colonial authorities during the period of Japanese colonial rule in Korea (1910-1945). The colonial experience can be divided into four different periods according to the four Educational Ordinances issued in 1911, 1922, 1938, and 1943 by the colonial government with each period corresponding to a historic event or context. The constitutive relevance of colonial discourse for an understanding of education can be found in the gradual transformation of the education sector in Korea under colonial rule. It is evident that Japanese colonial policy was inherently contradictory in principle and in practice. On the one hand it sought the assimilation of the Koreans, while on the other it maintained its discriminatory and exploitative practices. Such contradiction was obvious within the colonial education system. As the principal instrument of assimilation, education was ...

2010-12-01

266

An artificial neural network for directional comparison relaying of transmission lines  

Energy Technology Data Exchange (ETDEWEB)

Distance protection, differential protection and directional comparison schemes are presently used for protecting transmission lines. Directional comparison relays are set to respond to faults in the protection zone without intentional time delay and are, therefore, used where high-speed fault clearing is needed. Artificial Neural Networks (ANNs) can handle most situations which cannot be defined sufficiently for finding a deterministic solution. The design and testing of an ANN for directional comparison protection of transmission lines are presented in this paper. Training patterns were generated using voltage and current samples for faults at various locations along a transmission line. The faults were simulated using an electromagnetic transient program and a sample three-phase power system. The performance of the proposed discriminator was checked using data simulated for testing and the fault data recorded from 240 kV and 500 kV lines. Some of the test ...

1997-12-31

267

An argument for the chicken embryo as a model for the developmental toxicological effects of the polyhalogenated aromatic hydrocarbons (PHAHs)  

Energy Technology Data Exchange (ETDEWEB)

This article will present the argument that the chicken embryo is especially appropriate as an animal model for studying the mechanism of the developmental toxicological effects of the polyhalogenated aromatic hydrocarbons (PHAHs). The PHAHs are a group of toxicologically related compounds including, in part, the polychlorinated dibenzodioxins, dibenzofurans and biphenyls. The chicken (Gallus gallus) embryo is relatively sensitive to the toxicological effects of the PHAHs being approximately two orders of magnitude more sensitive than the mature bird. The chicken embryo has been used to demonstrate general toxicological teratogeneicity, hepatotoxicity and neurotoxicity. Many of these effects, or analogous effects, have also been observed in mammals and fish. Thus, most animals appear to respond to the PHAHs with a similar toxicological profile, indicating that many of the biomarkers used for the PHAHs are valid across a number of species, including the chicken. ...

1996-12-31

268

Adaptation of oral streptococci to low pH.  

Science.gov (United States)

The strategies employed by oral streptococci to resist the inimical influences of acidification reflect the diverse and dynamic niches of the human mouth. All of the oral streptococci are capable of rapid degradation of sugar to acidic end-products. As a result, the pH value of their immediate environment can plummet to levels where glycolysis and growth cease. At this point, the approaches for survival in acid separate the organisms. Streptococcus mutans, for example, relies on its F-ATPase, to protect itself from acidification by pumping protons out of the cells. S. salivarius responds by degrading urea to ammonia and S. sanguis produces ammonia by arginolysis. The mechanisms by which these organisms regulate their particular escape route are now being explored experimentally. The picture that emerges is that the acid-adaptive regulatory mechanisms of the oral streptococci differ markedly from those employed by Gram-negative bacteria. What remains to be ...

2000-01-01

269

A proposal for prevention of acute radiation hazard and social panic regarding orphan sources in Japan  

International Nuclear Information System (INIS)

To respond to an increase of social problems concerning orphan sources in Japan, a working group was formed in the Japan Health Physics Society. In this working group, we investigated how to prevent acute radiation hazard or social panic regarding orphan sources in scrap metal and detection system for orphan sources brought into scrap yards before recycle. For detection system in a scrap yard we conducted an experiment on detectability of monitoring instrument using a radiation source mixed in scrap metal on a truck. The result showed that it was not easy to detect even a high-level source if it was shielded by scrap metal. We also estimated detection limits for radioactive materials in scrap metal by calculation that was validated with experimental data. We summarized present status about orphan sources in Japan and proposed a categorization of orphan sources according to dose rates to deal with unknown sources in a scrap yard. Our report includes some proposals ...

2002-10-20

270

A new direct calculation method of response matrices using a Monte Carlo calculation  

Energy Technology Data Exchange (ETDEWEB)

A novel direct calculation method of response matrices on heterogeneous lattices by using the Monte Carlo method is proposed. These direct response matrices (DRMs) can be used in core calculations in place of the conventional homogenized lattice constants. The DRMs are formalized by four sub response matrices (sub-RMs) in order to respond to a core eigenvalue, k; thus the DRMs can be re-evaluated on each outer iteration in the core calculations. The sub-RMs can be evaluated by analyzing each neutron's trajectory from ordinary lattice calculations with the Monte Carlo code. Since these sub-RMs are calculated directly under an actual complex assembly geometry, i,e., without a homogenization process, intra-assembly heterogeneous effects can be reflected on global partial current balance calculations. With using two of the sub-RMs, which deal with neutron production probabilities for each fuel pin, and the obtained partial current balance, pin-wise neutron ...

1999-10-01

271

A dynamic model of a locomotive diesel engine and electrohydraulic governor  

Energy Technology Data Exchange (ETDEWEB)

As part of a comprehensive simulation of a prototype locomotive propulsion system, a detailed model has been developed which predicts the dynamic response of an experimental 2-stroke, turbocharged and intercooled diesel engine. Engine fueling and brake torque are computed from regression equations derived from an extensive data base. Corrections are applied to the calculated steady-state torque to account for dynamic deviations of in-cylinder trapped air-fuel ratio from the steady-state value. The engine simulation accurately represents the operation of the turbo-charger, which is gear-driven at low turbocharger speeds, and freewheels through an overrunning clutch when exhaust energy accelerates the turbocharger beyond its geared speed. Engine fueling level, ie, rack, is determined from a dynamic simulation of an electrohydraulic governor which responds to the difference between the desired and the actual engine speeds. The governor representation includes (1) ...

1988-01-01

272

A clinician's guide to surgical fires. How they occur, how to prevent them, how to put them out.  

Science.gov (United States)

Surgical fires--fires that occur on or in a surgical patient--are a rare but devastating complication of surgical procedures. They can happen during almost any kind of operation and can have dire consequences for both the patient and the hospital. The risk of surgical fires can be minimized as long as everyone on the surgical team understands how fires start and what to do when they occur. It's important to recognize the interaction among ignition sources, oxidizers, and fuels--the three sides of the classic fire triangle. What's more, staff members need to be alert to "hidden" fire risks, such as unsuspected oxygen-enriched atmospheres and less-than-obvious fuels. They also need to be drilled in the correct steps for responding to fires. In this guide, we describe the elements of surgical fires, including the types of equipment and materials that make up each side of the fire triangle. Through a series of case histories, we illustrate the many ways in which fires ...

2003-01-01

273

A New Landscape: Opportunities and Pitfalls for Universities Expanding in the Persian Gulf  

Science.gov (United States)

Dozens of universities--primarily from the United States, United Kingdom, and Australia--are eyeing the Gulf region as a largely untapped reservoir of academic potential and economic opportunity. During the last few years, UAE states like Dubai, Abu Dhabi, Qatar, and Ras al Khaymah have spent billions to entice top universities. And many colleges are responding--examples include New York University's campus in Abu Dhabi; Michigan State University's school in Dubai; and big names like Cornell, Northwestern, and Carnegie Mellon that have set up shop in Qatar. Typically, Western universities begin their foray into the Gulf by teaming with local investors. The colleges oversee the academic infrastructure while the investors front all operational costs. The partnerships are complicated. Some investors are mining the UAE's educational zeal for profit. In other cases, schools join forces with the region's numerous royal families, who are mostly interested in furthering ...

2008-12-01

274

A CANDU utility perspective on using world experience to manage Alloy 800 SG tube degradation  

Energy Technology Data Exchange (ETDEWEB)

In response to European operating experience regarding Alloy 800 steam generator (SG) tube cracking, New Brunswick Power Nuclear (NBPN) recognized two important shortcomings in the industry SG technical support framework. First, information exchange networks between utilities with Alloy 800 SG tubing should be strengthened. Second and more importantly, there is a need for consistent industry guidance for Alloy 800 SG tubing degradation management, supported by clear technical bases. It is NBPN's perspective that this guidance can be improved immediately using the extensive amount of laboratory and field data that is available for Alloys 600, 690, and 800, and EPRI methodology developed to predict the performance of Alloy 690. NBPN has initiated the development of a performance-based inspection plan. This effort is based on demonstrated improvement factors for Alloy 800, defined by the EPRI approach, and described in this paper. This approach is expected to assist utilities ...

2007-07-01

275

A CANDU utility perspective on using world experience to manage Alloy 800 SG tube degradation  

International Nuclear Information System (INIS)

In response to European operating experience regarding Alloy 800 steam generator (SG) tube cracking, New Brunswick Power Nuclear (NBPN) recognized two important shortcomings in the industry SG technical support framework. First, information exchange networks between utilities with Alloy 800 SG tubing should be strengthened. Second and more importantly, there is a need for consistent industry guidance for Alloy 800 SG tubing degradation management, supported by clear technical bases. It is NBPN's perspective that this guidance can be improved immediately using the extensive amount of laboratory and field data that is available for Alloys 600, 690, and 800, and EPRI methodology developed to predict the performance of Alloy 690. NBPN has initiated the development of a performance-based inspection plan. This effort is based on demonstrated improvement factors for Alloy 800, defined by the EPRI approach, and described in this paper. This approach is expected to assist utilities ...

2007-08-19

276

Watching Systems in graphs: an extension of Identifying Codes  

CERN Document Server

We introduce the notion of watching systems in graphs, which is a generalization of that of identifying codes. We give some basic properties of watching systems, an upper bound on the minimum size of a watching system, and results on the graphs which achieve this bound; we also study the cases of the paths and cycles, and give complexity results.

2010-01-01

277

Sources of toxicity and exposure information for identifying chemicals of high concern to children  

International Nuclear Information System (INIS)

Due to the large number of chemicals in commerce without adequate toxicity characterization data, coupled with an ineffective federal policy for chemical management in the United States, many states are grappling with the challenge to identify toxic chemicals that may pose a risk to human health and the environment. Specific populations (e.g., children, elderly) are particularly sensitive to these toxic chemicals. In 2008, the Children's Safe Product Act (CSPA) was passed in Washington State. The CSPA included specific requirements to identify High Priority Chemicals (HPCs) and Chemicals of High Concern to Children (CHCCs). To implement this legislation, a methodology was developed to identify HPCs from authoritative scientific and regulatory sources on the basis of toxicity criteria. Another set of chemicals of concern was then identified from authoritative sources, based on their potential exposure to ...

2010-11-01

278

Molecular cloning of the N-terminus of GTBP  

Energy Technology Data Exchange (ETDEWEB)

Defects in mismatch repair genes cause the genetic instability characteristic of hereditary nonpolyposis colorectal cancer and a subset of sporadic colon tumors. The newest member of the mismatch repair gene family, GTBP, has recently been identified as a partial cDNA. Here, we describe the isolation of its 5{prime} terminus, allowing definition of the entire coding region. Several polymorphisms within the 5{prime} end were identified and are presented. 13 refs., 1 fig.

1996-02-01

279

Identifying the Key Weaknesses in Network Security at Colleges.  

Science.gov (United States)

A new study identifies and ranks the 10 security gaps responsible for most outsider attacks on college computer networks. The list is intended to help campus system administrators establish priorities as they work to increase security. One network security expert urges that institutions utilize multiple security layers. (DB)

1999-12-01

280

Identification of unusual Campylobacter-like isolates from poultry products as Helicobacter pullorum  

DEFF Research Database (Denmark)

Twenty-six unclassified Campylobacter-like strains previously isolated from 15 chicken carcasses and caecal contents, together with two more strains isolated from chicken faeces on a different occasion, were identified as Helicobacter pullorum using various phenotypic identification methods. API Campy identification kits and a 16-test identification scheme developed for campylobacters failed to identify these bacteria, or identified them as Campylobacter spp. Eighteen strains (including the two isolated on a different occasion) were chosen for examination using a more comprehensive probabilistic identification scheme. Using this method, 14 of the 18 strains were identified as H. pullorum with ID scores > 95%; two strains were also identified as H. pullorum with lower ID scores. Of the remaining two strains, one was not identified with this scheme and the ...

1998-01-01

281

Epidemiological and clinical features of 1,149 persons with Lyme disease identified by laboratory-based surveillance in Connecticut.  

UK PubMed Central (United Kingdom)

Laboratory-based surveillance of Lyme disease in Connecticut during 1984 and 1985 identified 3,098 persons with suspected Lyme disease; 1,149 were defined as cases. Lyme disease incidence in Connecticut...Full Text Available

1989-05-01

282

Design study of copper toroidal field coils with bow shaping, demountable sliding joints, and active liquid-nitrogen cooling  

International Nuclear Information System (INIS)

The motivation for this design study has been to identify magnet designs for useful magnetic fusion experiments which minimize capital cost. Some possibly useful novel design features have been identified. 5 refs., 6 figs., 3 tabs.

1996-06-16

283

CFCC radiant burner assessment. Final report, April 1, 1992--July 31, 1994  

Energy Technology Data Exchange (ETDEWEB)

The objective of this work was to identify methods of improving the performance of gas-fired radiant burners through the use of Continuous Fiber Ceramic Composites (CFCCs). Methods have been identified to improve the price and performance characteristics of the porous surface burner. Results are described.

1994-11-01

284

Resource Management plan for the Oak Ridge Reservation. Volume 28, Wetlands on the Oak Ridge Reservation  

Energy Technology Data Exchange (ETDEWEB)

A survey of wetlands on the Oak Ridge Reservation (ORR) was conducted in 1990. Wetlands occurring on ORR were identified using National Wetlands Inventory (NWI) maps and field surveys. More than 120 sites were visited and 90 wetlands were identified. Wetland types on ORR included emergent communities in shallow embayments on reservoirs, emergent and aquatic communities in ponds, forested wetland on low ground along major creeks, and wet meadows and marshes associated with streams and seeps. Vascular plant species occurring on sites visited were inventoried, and 57 species were added to the checklist of vascular plants on ORR. Three species listed as rare in Tennessee were discovered on ORR during the wetlands survey. The survey provided an intensive ground truth of the wetlands identified by NWI and offered an indication of wetlands that the NWI remote sensing techniques did not detect.

1991-12-01

285

Resource Management plan for the Oak Ridge Reservation  

Energy Technology Data Exchange (ETDEWEB)

A survey of wetlands on the Oak Ridge Reservation (ORR) was conducted in 1990. Wetlands occurring on ORR were identified using National Wetlands Inventory (NWI) maps and field surveys. More than 120 sites were visited and 90 wetlands were identified. Wetland types on ORR included emergent communities in shallow embayments on reservoirs, emergent and aquatic communities in ponds, forested wetland on low ground along major creeks, and wet meadows and marshes associated with streams and seeps. Vascular plant species occurring on sites visited were inventoried, and 57 species were added to the checklist of vascular plants on ORR. Three species listed as rare in Tennessee were discovered on ORR during the wetlands survey. The survey provided an intensive ground truth of the wetlands identified by NWI and offered an indication of wetlands that the NWI remote sensing techniques did not detect.

1991-12-01

286

Plan for addressing issues relating to oil shale plant siting  

Energy Technology Data Exchange (ETDEWEB)

The Western Research Institute plan for addressing oil shale plant siting methodology calls for identifying the available resources such as oil shale, water, topography and transportation, and human resources. Restrictions on development are addressed: land ownership, land use, water rights, environment, socioeconomics, culture, health and safety, and other institutional restrictions. Descriptions of the technologies for development of oil shale resources are included. The impacts of oil shale development on the environment, socioeconomic structure, water availability, and other conditions are discussed. Finally, the Western Research Institute plan proposes to integrate these topics to develop a flow chart for oil shale plant siting. Western Research Institute has (1) identified relative topics for shale oil plant siting, (2) surveyed both published and unpublished information, and (3) identified data gaps and research ...

1987-09-01

287

Identification of optimum sites for power system stabilizer applications  

Energy Technology Data Exchange (ETDEWEB)

Many existing methods of identifying the optimum sites for installing power system stabilizers (PSSs) in multi-machine systems are restricted to the sequential PSS application, which considers the enhancement of damping of just one critical electromechanical mode at a time; the eigenstructure analysis of the open-loop system, which does not take the control matrix (i.e., the B matrix in the linearized model x = Ax + Bu for power systems) into consideration. This paper presents a method of identifying the optimum sites for installing power system stabilizers. The advantages of this method are: it can identify the optimum sites for installing PSSs so that several electrochemical modes are damped out simultaneously; it takes both the eigenstructure of the open-loop system and the control matrix into consideration.

1990-11-01

288

Environmental analysis of endocrine disrupting effects from hydrocarbon contaminants in the ecosystem. 1997 annual progress report  

Energy Technology Data Exchange (ETDEWEB)

'The overall objective of the basic research grant is to characterize the potential of common hydrocarbon contaminants in ecosystems to act as endocrine disruptors. The three major lines of research include (1) a biotechnology based screening system to identify potential hormone mimics and antagonists; (2) an animal screening system to identify biomarkers of endocrine effects. and (3) a literature review to identify compounds at a variety of DOE sites that need to be examined for endocrine disrupting effects. By relating results obtained from this research project to contamination problems at various DOE sites. CBR will provide data and information on endocrine disrupting contaminants to DOE for consideration in risk analyses for determining clean-up levels and priorities needed at the sites.'

1997-01-01

289

DNA barcoding as a tool for species identification in three forensic wildlife cases in South Africa  

British Library Electronic Table of Contents (United Kingdom)

Poaching of wildlife animals for subsistence and commercial purposes has lead to population declines in Africa. In forensic cases, a need exists to identify the species of origin of carcasses, meat or blood. In the study presented here, the mitochondrial COI gene was sequenced to determine the species of unknown samples in three suspect South African forensic wildlife cases. In two cases the unknown samples were identified as originating from domestic cattle (Bos taurus) and in the third case the sample was identified as common reedbuck (Redunca arundinum). This is the first report of the COI sequence of common reedbuck. The study highlights the need for accurate wildlife reference material from each country in order to convict wildlife cases.

2011-01-01

290

Assessment of coal gasification/hot gas cleanup based advanced gas turbine systems: Greenfield assessment. Final report  

Energy Technology Data Exchange (ETDEWEB)

Both the KRW fluidized-bed gasifier and the transport gasifier case studies were used for this assessment. The transport technology is a high-velocity circulating fluidized-bed reactor currently under development by The M.W. Kellogg Company. In the earlier assessment, seven design concepts or cases were identified; a process design was developed; major equipment items were identified; estimates of capital cost, operation and maintenance cost, and cost of electricity were developed; reliability was predicted; and development issues were identified for six studies. Three of the most probable cases were further evaluated for a Greenfield assessment in this report to adequately determine all costs independent of facilities at Plant Wansley.

1991-12-01

291

Assessment of coal gasification/hot gas cleanup based advanced gas turbine systems: Greenfield assessment  

Energy Technology Data Exchange (ETDEWEB)

Both the KRW fluidized-bed gasifier and the transport gasifier case studies were used for this assessment. The transport technology is a high-velocity circulating fluidized-bed reactor currently under development by The M.W. Kellogg Company. In the earlier assessment, seven design concepts or cases were identified; a process design was developed; major equipment items were identified; estimates of capital cost, operation and maintenance cost, and cost of electricity were developed; reliability was predicted; and development issues were identified for six studies. Three of the most probable cases were further evaluated for a Greenfield assessment in this report to adequately determine all costs independent of facilities at Plant Wansley.

1991-12-01

292

Application of remote sensing to identify coalfires in the Raniganj Coalbelt, India  

British Library Electronic Table of Contents (United Kingdom)

Raniganj and Jharia regions together have been for long the single largest coal supplier in India, now contributing about a quarter of the total output in the country. Numerous reasons such as improper mining techniques and policy, as well as unauthorized mining caused surface and subsurface coalfires in these areas. These coalfires burn millions of tonnes of valuable coal resources, creating severe environmental problems and posing enormous operational difficulties of mining. After first use of remote sensing as a tool to identify coalfires in 1960s, with the time, the efficiency of remote sensing to identify and monitoring coalfires has been well established by several researchers. With the knowledge of local geological setting and density sliced surface temperature image the spatial dis...

2006-01-01

293

Analysis of organic acids in the pyrohydrolysis distillate of (U,Pu) mixed carbide fuel by ion chromatography  

International Nuclear Information System (INIS)

The study reports the identification of different organic acids that are formed during the pyrohydrolysis of mixed carbide of uranium and plutonium using ion chromatography (IC). The identification of organic acids present in the pyrohydrolysis distillate is required to carry out interference free analysis of Cl and F. The study describes three stage isocratic separations with NaOH eluents having concentrations 2 mM, 10 mM and 50 mM respectively in order to separate and identify both aliphatic and aromatic acids. The present investigation identified formic, acetic, propionic, butyric, tartaric and oxalic acids in the distillate, however, aromatic acids could not be identified. (author)

2011-02-22

294

An evaluation of the UK skills base for toxicologists and ecotoxicologists, with focus on current and future requirements, particularly with regard to the skills required for hazard assessment of chemical substances including nanomaterials  

Environmental Research Database

Objectives1. To establish the present capacity and capability across all the sectors within the UK for - a) Undertaking research in the areas of toxicology and ecotoxicology and environmental hazard and risk assessment work on chemical subtances including emerging containments (e.g. enginerred nanomaterials); and b) Applying these skills in the policy and regulatory context. 2) The range of chemicals involved should include pharmaceutical and medical products, crop protection agents, biocides, vet [continued...]DescriptionThe aim of this project is to identify the current status of the scientific community, areas of expertise, and identify the gaps in skills, knowledge or recruitment. The project will use a questionnaire approach to obtain this information for all sectors of the business community. The analysis will identify the gaps in provision, and areas where investment is needed in future training and/or recruitment.

2009-01-15

295

misty somites, a maternal effect gene identified by transposon-mediated insertional mutagenesis in zebrafish that is essential for the somite boundary maintenance  

UK PubMed Central (United Kingdom)

Somite boundary formation is crucial for segmentation of vertebrate somites and vertebrae and skeletal muscle morphogenesis. Previously, we developed a Tol2 transposon-mediated...Full Text Available

2008-04-15

296

aHUS caused by complement dysregulation: new therapies on the horizon  

UK PubMed Central (United Kingdom)

Atypical hemolytic uremic syndrome (aHUS) is a heterogeneous disease that is caused by defective complement regulation in over 50% of cases. Mutations have been identified in genes encoding both complement...Full Text Available

2011-01-01

297

Workshop to identify critical windows of exposure for children's health: neurobehavioral work group summary.  

UK PubMed Central (United Kingdom)

This paper summarizes the deliberations of a work group charged with addressing specific questions relevant to risk estimation in developmental neurotoxicology. We focused on eight questions. a) Does...Full Text Available

2000-06-01

298

Visual Genome-Wide RNAi Screening to Identify Human Host Factors Required for Trypanosoma cruzi Infection  

UK PubMed Central (United Kingdom)

The protozoan parasite Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical infection that affects millions of people in the Americas. Current chemotherapy...Full Text Available

299

Variable Pathogenicity Determines Individual Lifespan in Caenorhabditis elegans  

UK PubMed Central (United Kingdom)

A common property of aging in all animals is that chronologically and genetically identical individuals age at different rates. To unveil mechanisms that influence aging variability, we identified markers...Full Text Available

2011-04-01

300

Validation of the treatment identification strategy of the HEDIS addiction quality measures: concordance with medical record review  

UK PubMed Central (United Kingdom)

BackgroundStrategies to accurately identify the occurrence of specific health care events in administrative data is central to many quality improvement and research efforts. Many...Full Text Available

301

Using microarrays to identify positional candidate genes for QTL: the case study of ACTH response in pigs  

UK PubMed Central (United Kingdom)

BackgroundMicroarray studies can supplement QTL studies by suggesting potential candidate genes in the QTL regions, which by themselves are too large to provide a limited selection...Full Text Available

302

Using Regulatory and Epistatic Networks to Extend the Findings of a Genome Scan: Identifying the Gene Drivers of Pigmentation in Merino Sheep  

UK PubMed Central (United Kingdom)

Extending genome wide association analysis by the inclusion of gene expression data may assist in the dissection of complex traits. We examined piebald, a pigmentation phenotype in both human and Merino...Full Text Available

303

Use of solid state nuclear track detectors for radon concentration measurements indoors  

International Nuclear Information System (INIS)

An indoor radioactive survey is being conducted in an Italian district. Preliminary results identified a zone with significant radioactive levels, in which a new specific survey has been planned. In this paper attention is dedicated mainly to radon measurement technique and results.

304

Uptake of injected 125I-ricin by rat liver in vivo. Subcellular distribution and characterization of the internalized ligand.  

UK PubMed Central (United Kingdom)

Subcellular-fractionation techniques were used to characterize the endocytic pathway followed by ricin in rat liver in vivo and tentatively identify the site(s) at which the ricin interchain disulphide...Full Text Available

1992-05-15

305

Tumor-derived extracellular mutations of PTPRT/PTP? are deficient in cell adhesion  

UK PubMed Central (United Kingdom)

Receptor protein tyrosine phosphatase T (PTPRT/PTPρ) is frequently mutated in human cancers including colon, lung, gastric and skin cancers. More than half of the identified tumor-derived...Full Text Available

2008-07-01

306

Treatment with Selective Serotonin Reuptake Inhibitors and Mirtapazine Results in Differential Brain Activation by Visual Erotic Stimuli in Patients with Major Depressive Disorder  

UK PubMed Central (United Kingdom)

ObjectiveThe objective of this study was to identify patterns of brain activation elicited by erotic visual stimuli in patients treated with either Selective Serotonin Reuptake Inhibitors...Full Text Available

2009-06-01

307

Trauma service cost: the real story.  

UK PubMed Central (United Kingdom)

OBJECTIVE: The objective was to define and characterize the costs associated with trauma care at a level I trauma center. Once the costs were identified, attending physician-led teams were designed...Full Text Available

1998-05-01

308

The feasibility of using pattern recognition software to measure the influence of computer use on the consultation  

UK PubMed Central (United Kingdom)

BackgroundA key feature of a good general practice consultation is that it is patient-centred. A number of verbal and non-verbal behaviours have been identified as important to establish...Full Text Available

309

The Relationship between Leishmaniasis and AIDS: the Second 10 Years  

UK PubMed Central (United Kingdom)

Summary: To date, most Leishmania and human immunodeficiency virus (HIV) coinfection cases reported to WHO come from Southern Europe. Up to the year 2001, nearly 2,000 cases of coinfection were identified,...Full Text Available

2008-04-01

310

The Mitochondrial Isovaleryl-Coenzyme A Dehydrogenase of Arabidopsis Oxidizes Intermediates of Leucine and Valine Catabolism1  

UK PubMed Central (United Kingdom)

We recently identified a cDNA encoding a putative isovaleryl-coenzyme A (CoA) dehydrogenase in Arabidopsis (AtIVD). In animals, this homotetrameric enzyme is located in mitochondria and catalyzes the...Full Text Available

2001-06-01

311

The Challenge of Basic Education for All.  

Science.gov (United States)

Clarifies the concept of universal basic education. Highlights the need for performance criteria and ways to measure literacy attainment. Identifies issues related to improving primary education, seeing adult literacy as its necessary complement. Underscores the substantial resources required to achieve universal basic education. (CH)

1988-12-01

312

The Arabidopsis ref2 Mutant Is Defective in the Gene Encoding CYP83A1 and Shows Both Phenylpropanoid and Glucosinolate Phenotypes  

UK PubMed Central (United Kingdom)

The Arabidopsis ref2 mutant was identified in a screen for plants having altered fluorescence under UV light. Characterization of the ref2 mutants showed that they...Full Text Available

2003-01-01

313

The Anopheles gambiae glutathione transferase supergene family: annotation, phylogeny and expression profiles  

UK PubMed Central (United Kingdom)

BackgroundTwenty-eight genes putatively encoding cytosolic glutathione transferases have been identified in the Anopheles gambiae genome. We manually annotated these...Full Text Available

314

Terminal-differential algorithm for identification of local non homogeneity in article  

International Nuclear Information System (INIS)

Terminal-differential algorithm for identification of local nonhomogeneities in items under control is developed on the basis of measurements of X-ray or gamma-radiation weakening. The algorithm may be applied by developing radiation schemes of nondestructive control, identifying inadmissible inclusions in the object under study

315

Tachyons and the instability of physical systems  

International Nuclear Information System (INIS)

The problem on the ratio between the instability of physical systems and tachyons is discussed. It is shown that the tachyons participation in the real physical process of the system rearranging does not contradict any principles. It is noted that the tachyons constitute the most significant element of the systems, identifying the instability relative to the phase transition into the stable state.

316

Syk Tyrosine Kinase Acts as a Pancreatic Adenocarcinoma Tumor Suppressor by Regulating Cellular Growth and Invasion  

UK PubMed Central (United Kingdom)

We have identified the nonreceptor tyrosine kinase syk as a marker of differentiation/tumor suppressor in pancreatic ductal adenocarcinoma (PDAC). Syk expression is lost in poorly differentiated PDAC...Full Text Available

2009-12-01

317

Swift Science Center - HEASARC - NASA  

Science.gov (United States)

Apr 20, 2009 ... "YY" is the 2-digit filter identifier .... In our example you can see a point- like optical/UV source in each of the filters at the ... The "sigma" paramter gives the detection threshold in terms of Gaussian sigma. ...

318

Susceptibility of human primary neuronal cells to Xenotropic Murine Leukemia Virus-related (XMRV) virus infection  

UK PubMed Central (United Kingdom)

BackgroundXenotropic Murine Leukemia Virus-related (XMRV) virus is a recently identified mouse gammaretrovirus that has the ability to infect certain human cells. In this study,...Full Text Available

319

Survival of HIV-Infected Adolescents on Antiretroviral Therapy in Uganda: Findings from a Nationally Representative Cohort in Uganda  

UK PubMed Central (United Kingdom)

BackgroundAdolescents have been identified as a high-risk group for poor adherence to and defaulting from combination antiretroviral therapy (cART) care. However, data on outcomes...Full Text Available

320

Surfactant protein A, an innate immune factor, is expressed in the vaginal mucosa and is present in vaginal lavage fluid  

UK PubMed Central (United Kingdom)

Surfactant protein A (SP-A), first identified as a component of the lung surfactant system, is now recognized to be an important contributor to host defence mechanisms. SP-A can facilitate phagocytosis...Full Text Available

2004-01-01

321

Sugarcane pests and their management  

Science.gov (United States)

This book chapter discusses sugarcane culture and history, describes arthropod biologies and injury, and identifies sugarcane pest management factors to consider for people interested in commercial sugarcane production. Arthropod groups include 10 orders and 40 families. Sugarcane pest management ...

322

Study on the transient piping vibration of power plant. Secondary piping system of Wolsung 1 unit.  

Science.gov (United States)

In order to maintain a safe operation and availability of generating facilities, qualitative and quantitative assessment of piping vibration was performed vibration sources and damages of piping support was identified on the second piping system of Wolsun...

1996-01-01

323

Statistical methods for the blood beryllium lymphocyte proliferation test.  

UK PubMed Central (United Kingdom)

The blood beryllium lymphocyte proliferation test (BeLPT) is a modification of the standard lymphocyte proliferation test that is used to identify persons who may have chronic beryllium disease. A major...Full Text Available

1996-10-01

324

Some design considerations for solar-powered aircraft  

Energy Technology Data Exchange (ETDEWEB)

Performance and operating characteristics are presented for a solar powered aircraft intended to remain aloft for long periods. The critical technologies which limit the performance are identified. By using the techniques presented, the effects of variation in the system parameters are studied. Practical design consideration are discussed.

1980-06-01

325

Sequential Molecular and Cellular Events during Neoplastic Progression: A Mouse Syngeneic Ovarian Cancer Model1  

UK PubMed Central (United Kingdom)

AbstractStudies performed to identify early events of ovarian cancer and to establish molecular markers to support early detection and development of chemopreventive regimens have been...Full Text Available

2005-10-01

326

Self-Medication: Initial Treatments Used by Patients Seen in an Ophthalmologic Emergency Room  

UK PubMed Central (United Kingdom)

OJECTIVEThis study seeks to identify practices of self-medication in the treatment of ocular emergencies. We examine patients’ use of both homemade preparations and manufactured...Full Text Available

2009-08-01

327

Selection of Inhibitor-Resistant Viral Potassium Channels Identifies a Selectivity Filter Site that Affects Barium and Amantadine Block  

UK PubMed Central (United Kingdom)

BackgroundUnderstanding the interactions between ion channels and blockers remains an important goal that has implications for delineating the basic mechanisms of ion channel function...Full Text Available

328

Retrospective identification and characterization of mild cognitive impairment from a prospective population cohort  

UK PubMed Central (United Kingdom)

ObjectivesMild Cognitive Impairment (MCI) case-finding criteria have low specificity in general population studies. The present study retrospectively identifies cases...Full Text Available

2010-08-01

329

Retention, Learning by Doing, and Performance in Emergency Medical Services  

UK PubMed Central (United Kingdom)

ObjectivesTo examine the strength of the volume–outcome relationship among paramedics, a group of providers that has not been previously studied in this context. By identifying...Full Text Available

2009-06-01

330

Repeated tumor oximetry to identify therapeutic window during metronomic cyclophosphamide treatment of 9L gliomas  

UK PubMed Central (United Kingdom)

Malignant gliomas are aggressive and angiogenic tumors with high VEGF content. Consequently, approaches such as metronomic chemotherapy, which have an antiangiogenic effect, are being investigated....Full Text Available

2011-07-01

331

Renewable energy and the ODA energy efficient strategy  

Energy Technology Data Exchange (ETDEWEB)

The energy strategy of the UK Overseas Development Administration is outlined with specific emphasis on energy efficiency and renewable energies. Based on 29 case studies concerning projects and programmes in both developed and developing countries, critical success factors for renewable energy projects are identified. UK)

1995-12-31

332

Reduced thermal sensitivity and Nav1.8 and TRPV1 channel expression in sensory neurons of aged mice  

UK PubMed Central (United Kingdom)

Sensory neurons in aging mammals undergo changes in anatomy, physiology and gene expression that correlate with reduced sensory perception. In this study we compared young and aged mice to identify...Full Text Available

2006-06-01

333

Reduced Accumulation of ABA during Water Stress in a Molybdenum Cofactor Mutant of Barley 1  

UK PubMed Central (United Kingdom)

A barley (Hordeum vulgare L.) mutant (Az34) has been identified with low basal levels of abscisic acid (ABA) and with reduced capacity for producing ABA in response to water stress....Full Text Available

1989-06-01

334

Reaction of human albumin with aspirin in vitro: mass spectrometric identification of acetylated lysines 199, 402, 519, and 545  

UK PubMed Central (United Kingdom)

The aspirin esterase activity of human plasma is due to butyrylcholinesterase and albumin. Our goal was to identify the amino acid residues involved in the aspirin esterase activity of albumin....Full Text Available

2010-03-01

335

Radiographic monitoring of incidental abdominal aortic aneurysms: a retrospective population-based cohort study  

UK PubMed Central (United Kingdom)

BackgroundAn abdominal aortic aneurysm (AAA) that is identified when the abdomen is imaged for some other reason is known as an incidental AAA. No population-based studies have...Full Text Available

336

Queensland resources of black coal, December 1988  

Energy Technology Data Exchange (ETDEWEB)

This assessment of Queensland's resources of black coal has been prepared by the Coal and Oil Shale Resources Assessment and Development Subprogram, Queensland Department of Mines, in accordance with the 'Code for Reporting of Identified Coal Resources and Reserves'.

1989-01-01

337

Quality assessment of reporting of randomization, allocation concealment, and blinding in traditional chinese medicine RCTs: A review of 3159 RCTs identified from 260 systematic reviews  

UK PubMed Central (United Kingdom)

BackgroundRandomized controlled trials (RCTs) which are of poor quality tend to exaggerate the effect estimate and lead to wrong or misleading conclusions. The aim of this study...Full Text Available

338

Psychology and health: contributions of psychology to the improvement of health and health care  

UK PubMed Central (United Kingdom)

Psychology as both a science and a profession has been closely identified with other disciplines in the broad field of health since the turn of the present century. Recent advances in health care have...Full Text Available

1987-01-01

339

Proteomic approach with LCMS-IT-TOF identified an increase of Rab33B after transient focal cerebral ischemia in mice  

UK PubMed Central (United Kingdom)

BackgroundSeveral proteins are known to be markedly expressed in the brain during cerebral ischemia; however, the changes in protein profiles within the ischemic brain after an ischemic...Full Text Available

340

Proteome of human colon cancer stem cells: A comparative analysis  

UK PubMed Central (United Kingdom)

AIM: To isolate and identify the biological characteristics of human colon cancer stem cells (SW1116 cells) and further study their proteome.METHODS: SW1116 cells were isolated and cultured with...Full Text Available

2011-03-14

341

Prosthesis use in persons with lower- and upper-limb amputation  

UK PubMed Central (United Kingdom)

This study identified clinical (e.g., etiology) and demographic factors related to prosthesis use in persons with upper- and lower-limb amputation (ULA and LLA, respectively) and the effect...Full Text Available

2008-01-01

342

Proline Betaine Accumulation and Metabolism in Alfalfa Plants under Sodium Chloride Stress. Exploring Its Compartmentalization in Nodules1  

UK PubMed Central (United Kingdom)

The osmoprotectant Pro betaine is the main betaine identified in alfalfa (Medicago sativa). We have investigated the long-term responses of nodulated alfalfa plants to salt stress,...Full Text Available

2004-07-01

343

Progesterone for the prevention of preterm birth: indications, when to initiate, efficacy and safety  

UK PubMed Central (United Kingdom)

Preterm birth is the leading cause of neonatal mortality and morbidity and long-term disability of non-anomalous infants. Previous studies have identified a prior early spontaneous preterm birth as...Full Text Available

2009-01-01

344

Predictors of disability in a longitudinal sample of patients with rheumatoid arthritis.  

UK PubMed Central (United Kingdom)

Information from the Health Assessment Questionnaire (HAQ) is used to identify which variables measured in 1981 successfully predict the severity of disease in 1989 and the eight year change in severity...Full Text Available

1992-05-01

345

Predictors for presence and abundance of small mammals in households of villages endemic for commensal rodent plague in Yunnan Province, China  

UK PubMed Central (United Kingdom)

BackgroundNinety-one rodent plague epidemics have occurred in Lianghe county, Yunnan Province, China, between 1990 and 2006. This study aimed to identify predictors for the presence...Full Text Available

346

Predicting outcome of rethoracotomy for suspected pericardial tamponade following cardio-thoracic surgery in the intensive care unit  

UK PubMed Central (United Kingdom)

ObjectivesPericardial tamponade after cardiac surgery is difficult to diagnose, thereby rendering timing of rethoracotomy hard. We aimed at identifying factors predicting the outcome...Full Text Available

347

Potentially Inappropriate Prescribing of Benzodiazepines for Older Adults and Risk of Falls During a Hospital Stay: A Descriptive Study  

UK PubMed Central (United Kingdom)

Background:Falls have been identified as a potential adverse event associated with the administration of psychotropic medications to older patients.Objective:The...Full Text Available

2009-07-01

348

Polyantigenic Interferon-? Responses Are Associated with Protection from TB among HIV-Infected Adults with Childhood BCG Immunization  

UK PubMed Central (United Kingdom)

BackgroundSurrogate immunologic markers for natural and vaccine-mediated protection against tuberculosis (TB) have not been identified.MethodsHIV-infected...Full Text Available

349

Phosphorylated PmrA Interacts with the Promoter Region of ugd in Salmonella enterica Serovar Typhimurium  

UK PubMed Central (United Kingdom)

The Salmonella PmrA-PmrB system controls the expression of genes necessary for polymyxin B resistance. Four loci were previously identified as part of the regulon, and interaction of...Full Text Available

2000-07-01

350

Patient-Care Practices Associated With an Increased Prevalence Of Hepatitis C Virus Infection among Chronic Hemodialysis Patients  

UK PubMed Central (United Kingdom)

ObjectiveTo identify patient-care practices related to an increased prevalence of hepatitis C virus (HCV) infection among chronic hemodialysis patients.Full Text Available

2011-05-01

351

Past, present, and future of mutagens in cooked foods.  

UK PubMed Central (United Kingdom)

Mutation assay with Salmonella typhimurium enabled us to detect various types of mutagens in cooked foods. A series of mutagenic heterocyclic amines has been isolated and identified in broiled fish...Full Text Available

1986-08-01

352

Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques.  

UK PubMed Central (United Kingdom)

In an earlier report, we used differential cloning to identify genes that might be critical in controlling arterial neointima formation (Giachelli, C., N. Bae, D. Lombardi, M. Majesky, and S. Schwartz....Full Text Available

1993-10-01

353

Online quasi-continuous measurement of organic acids in the atmosphere  

Energy Technology Data Exchange (ETDEWEB)

The concentration of some organic acids in the atmosphere was determined using a wet effluent diffusion denuder-aerosol collector coupled with Ion Chromatography. Three organic acids and four inorganic anions were identified and quantified in the air sample, taken from the backyard of PSI. (author)

2002-03-01

354

Oil palm (Elaeis guineensis Jacq.) tissue culture ESTs: Identifying genes associated with callogenesis and embryogenesis  

UK PubMed Central (United Kingdom)

BackgroundOil palm (Elaeis guineensis Jacq.) is one of the most important oil bearing crops in the world. However, genetic improvement of oil palm through conventional...Full Text Available

355

Nuclear Organization and Dynamics of 7SK RNA in Regulating Gene Expression  

UK PubMed Central (United Kingdom)

Noncoding RNAs play important roles in various aspects of gene regulation. We have identified 7SK RNA to be enriched in nuclear speckles or interchromatin granule clusters (IGCs), a subnuclear domain...Full Text Available

2010-12-01

356

Novel high-throughput screening system for identifying STAT3-SH2 antagonists  

International Nuclear Information System (INIS)

Constitutive activation of the oncogenic transcription factor STAT3 frequently occurs in various human malignancies. STAT3 activation involves dimerization via intermolecular pTyr-SH2 interaction. Thus, antagonizing this interaction is a feasible approach to inhibit STAT3 activation for cancer therapy. In order to identify selective STAT3 inhibitors, we developed a biochemical HTS system based on AlphaScreen technology, which measures the abilities of test compounds to antagonize pTyr-SH2 interactions. We screened our chemical libraries using this system and identified 5,15-diphenylporphyrin (5,15-DPP) as a selective STAT3-SH2 antagonist. Selective inhibition of STAT3 nuclear translocation and DNA biding activity was observed in cells treated with 5,15-DPP. IL-6-dependent dimerization of STAT3, c-myc promoter binding and c-myc protein expression were all suppressed by 5,15-DPP, whereas no decrement in either expression or phosphorylation level ...

2009-03-13

357

Nitric Oxide Emissions from Soybean Leaves during in Vivo Nitrate Reductase Assays 1  

UK PubMed Central (United Kingdom)

Recent work identified acetaldehyde oxime as the predominant product purged by inert gases from anaerobic in vivo nitrate reductase (NR) assays of soybean (Glycine max...Full Text Available

1987-09-01

358

Mutation analysis of 272 Spanish families affected by autosomal recessive retinitis pigmentosa using a genotyping microarray  

UK PubMed Central (United Kingdom)

PurposeRetinitis pigmentosa (RP) is a genetically heterogeneous disorder characterized by progressive loss of vision. The aim of this study was to identify the causative mutations...Full Text Available

359

Mutation Spectrum of EYS in Spanish Patients with Autosomal Recessive Retinitis Pigmentosa  

UK PubMed Central (United Kingdom)

Retinitis pigmentosa (RP) is a heterogeneous group of inherited retinal dystrophies characterised ultimately by the loss of photoreceptor cells. We have recently identified a new gene (EYS) encoding...Full Text Available

2010-11-01

360

Multicenter Case-Control Study on Restless Legs Syndrome in Multiple Sclerosis: the REMS Study  

UK PubMed Central (United Kingdom)

Study objectives:To verify the existence of a symptomatic form of restless legs syndrome (RLS) secondary to multiple sclerosis (MS) and to identify possible associated risk factors.Design:Prospective,...Full Text Available

2008-07-01

361

Morphology of inhibitory and excitatory interneurons in superficial laminae of the rat dorsal horn  

UK PubMed Central (United Kingdom)

If we are to stand any chance of understanding the circuitry of the superficial dorsal horn, it is imperative that we can identify which classes of interneuron are excitatory and which are inhibitory....Full Text Available

2007-10-15

362

Monitoring the Simultaneous Presentation of Spatialized Speech Signals in a Virtual Acoustic Environment.  

Science.gov (United States)

The effect of spatial auditory information on a listener's ability to detect, identify, and monitor multiple simultaneous speech signals was evaluated using virtual audio technology. Factorial combinations of three variables - the number of localized spee...

1998-01-01

363

Monitoring of NK-Cell Immunotherapy using non-invasive Imaging Modalities  

UK PubMed Central (United Kingdom)

Cancer immunotherapies can be guided by cellular imaging techniques, which can identify the presence or absence of immune-cell accumulation in the tumor tissue in-vivo and in real time. This...Full Text Available

2010-08-01

364

Molecular cloning and nucleotide sequence of the beta-lytic protease gene from Achromobacter lyticus.  

UK PubMed Central (United Kingdom)

Two bacteriolytic enzymes secreted by Achromobacter lyticus M497-1 were purified and identified as being very similar (considering their amino acid composition and N-terminal sequence) to alpha- and...Full Text Available

1990-11-01

365

Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T cell responses to Cryptococcus neoformans  

UK PubMed Central (United Kingdom)

The fungus Cryptococcus neoformans is a major cause of morbidity and mortality in patients with impaired CD4+ T cell function, particularly those with AIDS. To identify...Full Text Available

2001-08-28

366

Misclassification of Patients with Spinocerebellar Ataxia as Having Psychogenic Postural Instability Based on Computerized Dynamic Posturography  

UK PubMed Central (United Kingdom)

Specific criteria have been developed based on computerized dynamic posturography (CDP) to assist clinicians in identifying patients with psychogenic balance problems (Cyr and Cevette, Full Text Available

367

Milk fever and alert downer cows: Does hypophosphatemia affect the treatment response?  

UK PubMed Central (United Kingdom)

The purpose of this prospective cohort study was to identify factors that place a dairy cow with uncomplicated milk fever (MF) at significant risk of becoming an alert downer cow (ADC) and to verify...Full Text Available

2007-05-01

368

Microsoft Word - ~4679716.doc  

Wastenet

UNEP will provide in the first CPR quarterly report of 2011 the financial statements for 2010. ...for assessing and rating programme performance UNEP to work with the CPR to identify better ways of streamlining reporting requirements ...in 2011 to achieve the ratios requested by the CPR dependent on receipt of contributions originally planned for the

369

Measurement of Sexual Functioning After Spinal Cord Injury: Preferred Instruments  

UK PubMed Central (United Kingdom)

Background/Objective:To determine the utility of certain instruments to assess sexuality and fertility after SCI, an expert panel identified key areas to study and evaluated...Full Text Available

2009-06-01

370

Mapping neuropeptide expression by mass spectrometry in single dissected identified neurons from the dorsal ganglion of the nematode Ascaris suum  

UK PubMed Central (United Kingdom)

We have developed a method for dissecting single neurons from the nematode Ascaris suum, in order to determine their peptide content by mass spectrometry (MS). In this paper,...Full Text Available

2010-07-21

371

Manganese  

Science.gov (United States)

Sources of manganese are identified. Uptake and distribution of manganese in plants and man are discussed, and the role of manganese in metabolism is described. The epidemiology of manganese toxicity is outlined, permissible air concentrations are listed, and the symptoms of manganese toxicity and deficiency are described. 555 references, 32 tables.

1973-01-01

372

MFR, a Putative Receptor Mediating the Fusion of Macrophages  

UK PubMed Central (United Kingdom)

We had previously identified a macrophage surface protein whose expression is highly induced, transient, and specific, as it is restricted to actively fusing macrophages in vitro and in vivo. This protein...Full Text Available

1998-11-01

373

Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage Fc?RI, Fc?RIII, and Fc?RIV  

UK PubMed Central (United Kingdom)

Despite the demonstrated clinical efficacy of CD20 monoclonal antibody (mAb) for lymphoma therapy, the in vivo mechanisms of tumor depletion remain controversial and variable. To identify the molecular...Full Text Available

2008-08-15

374

Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies  

UK PubMed Central (United Kingdom)

Recently, genome-wide association studies (GWAS) have linked the human LIN28B locus to height and timing of menarche [1-Full Text Available

2010-07-01

375

Light-Dependent Regulation of Cyanobacterial Phytochrome Expression  

UK PubMed Central (United Kingdom)

A histidine kinase protein (Cph1) with sequence homology and spectral characteristics very similar to those of the plant phytochrome has been recently identified in the cyanobacterium Synechocystis...Full Text Available

2000-01-01

376

Life history plasticity after attaining a dietary threshold for reproduction is associated with protein storage in flesh flies  

UK PubMed Central (United Kingdom)

SummaryBody condition affects the timing and magnitude of life history transitions. Therefore, identifying proximate mechanisms...Full Text Available

2008-12-01

377

Lameness, Activity Time-Budgets, and Estrus Expression in Dairy Cattle  

UK PubMed Central (United Kingdom)

The aim of the present study was to identify specific behavioral patterns that contribute to diminished estrus expression in lame cows. Behavioral scan and focal sampling were used to examine...Full Text Available

2008-12-01

378

Laboratory Evaluation of Base Materials for Neutralization of the Contaminated Aquifer at the F-Area Seepage Basins  

Energy Technology Data Exchange (ETDEWEB)

Laboratory studies were performed to support field-testing of base injection into the F-Area Seepage Basins groundwater. The general purpose of these experiments is to provide information to guide the test of base injection and to identify potential adverse effects.

2001-09-11

379

Isolation of caprine arthritis encephalitis virus from goats in Mexico.  

UK PubMed Central (United Kingdom)

A lentivirus was isolated from 2 goats in Mexico that were seropositive to caprine arthritis encephalitis virus (CAEV) by the agar gel immunodiffusion (AGID) test. The lentivirus was identified as CAEV...Full Text Available

1999-07-01

380

Isolation and identification of a cobamide coenzyme from the tapeworm Spirometra mansonoides.  

Science.gov (United States)

A light-sensitive vitamin B12 derivative has been extracted from the adult cestode, Spirometra mansonoides. This corrinoid was identified as the cobamide coenzyme, adenosylcobalamin, by its chromatographic, chemical, and spectral properties. PMID:1003284

1976-12-01

381

In Vivo RNAi Screening Identifies Regulators of Actin Dynamics as Key Determinants of Lymphoma Progression  

UK PubMed Central (United Kingdom)

Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic...Full Text Available

2009-10-01

382

Improving Knowledge and Attitudes towards Depression: a controlled trial among Chinese medical students  

UK PubMed Central (United Kingdom)

BackgroundEstablishing an evidence-based method of improving knowledge and attitudes concerning depression has been identified as a priority in Chinese medical education. The purpose...Full Text Available

383

Immunoradiometric measurement of the factor VIII procoagulant antigen.  

UK PubMed Central (United Kingdom)

A fluid-phase immunoradiometric assay has been developed which identifies an antigen on the Factor VIII (antihemophilic factor) procoagulant protein. This sensitive and quantitative assay is not influenced...Full Text Available

1978-11-01

384

Identifying related L1 retrotransposons by analyzing 3' transduced sequences  

UK PubMed Central (United Kingdom)

BackgroundA large fraction of the human genome is attributable to L1 retrotransposon sequences. Not only do L1s themselves make up a significant portion of the genome, but L1-encoded...Full Text Available

2003-01-01

385

Identifying barriers to Papanicolaou smear screening in Korean women: Korean National Health and Nutrition Examination Survey 2005  

UK PubMed Central (United Kingdom)

ObjectiveThis study was conducted to provide a nationwide analysis on barriers to cervical cancer screening in Korea.MethodsData used for this study...Full Text Available

2010-06-01

386

Identifying and validating biomarkers for Alzheimer's disease  

UK PubMed Central (United Kingdom)

The identification and validation of biomarkers for diagnosing Alzheimer's disease (AD) and other forms of dementia are increasingly important. To date, ELISA measurement of β-amyloid(1–42),...Full Text Available

2011-01-01

387

Identification of cell cycle-related regulatory motifs using a kernel canonical correlation analysis  

UK PubMed Central (United Kingdom)

BackgroundGene regulation is a key mechanism in higher eukaryotic cellular processes. One of the major challenges in gene regulation studies is to identify regulators affecting the...Full Text Available

388

Identification of a stem cell candidate in the normal human prostate gland  

UK PubMed Central (United Kingdom)

Stem cells of the human prostate gland have not yet been identified utilizing a structural biomarker. We have discovered a new prostatic epithelial cell phenotype-expressing cytokeratin 6a (Ck6a+...Full Text Available

2005-03-01

389

Identification of a Copper-Responsive Two-Component System on the Chromosome of Escherichia coli K-12  

UK PubMed Central (United Kingdom)

Using a genetic screen we have identified two chromosomal genes, cusRS (ylcA ybcZ), from Escherichia coli K-12 that encode a two-component, signal...Full Text Available

2000-10-01

390

Identification of CTX-M-14 Extended-Spectrum ?-Lactamase in Clinical Isolates of Shigella sonnei, Escherichia coli, and Klebsiella pneumoniae in Korea  

UK PubMed Central (United Kingdom)

CTX-M-14 β-lactamase was identified in a stool isolate of Shigella sonnei and in blood isolates of Escherichia coli (one isolate) and Klebsiella pneumoniae...Full Text Available

2001-10-01

391

Identification and mobilization by cointegrate formation of a nodulation plasmid in Rhizobium trifolii.  

UK PubMed Central (United Kingdom)

A nodulation plasmid, pRtr-514a, of molecular size 180 megadaltons (Mdal) was identified in Rhizobium trifolii strain NZP514. This plasmid was absent in both spontaneous and heat-cured Nod- derivatives...Full Text Available

1982-07-01

392

Identification and Characterization of CPS1 as a Hyaluronic Acid Synthase Contributing to the Pathogenesis of Cryptococcus neoformans Infection?  

UK PubMed Central (United Kingdom)

Cryptococcus neoformans is a pathogenic yeast that often causes devastating meningoencephalitis in immunocompromised individuals. We have previously identified the C. neoformans...Full Text Available

2007-08-01

393

High-Risk Populations Identified in Childhood Cancer Survivor Study Investigations: Implications for Risk-Based Surveillance  

UK PubMed Central (United Kingdom)

Childhood cancer survivors often experience complications related to cancer and its treatment that may adversely affect quality of life and increase the risk of premature death. The purpose of this...Full Text Available

2009-05-10

394

High affinity of lead for fetal haemoglobin.  

UK PubMed Central (United Kingdom)

In-vitro experiments using 203Pb were performed to identify lead-binding components in human haemoglobin. Sephadex A-50 ion-exchange chromatography of haemolysate showed that different types of haemoglobin...Full Text Available

1980-08-01

395

Heterogeneous catalytic alcoholysis of benzonitrile  

Energy Technology Data Exchange (ETDEWEB)

The authors investigate the possibility of the direct heterogeneous catalytic synthesis of ethylbenzoate from benzonitrile. The catalysts tested were oxides of aluminium, titanium, and vanadium. The main conversion product detected chromatographically was ethylbenzoate; benzaldehyde, benzamide, and benzanilide were also identified. Aluminium oxide was found to be the most effective catalyst.

1986-04-01

396

Heritability of Measures of Kidney Disease Among Zuni Indians: The Zuni Kidney Project  

UK PubMed Central (United Kingdom)

BackgroundThe long-term goal of the GKDZI (Genetics of Kidney Disease in Zuni Indians) Study is to identify genes, environmental factors, and genetic-environmental...Full Text Available

2010-08-01

397

Hepatic stellate cells and parasite-induced liver fibrosis  

UK PubMed Central (United Kingdom)

Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important...Full Text Available

398

Health professionals rarely record history of complementary and alternative medicines  

UK PubMed Central (United Kingdom)

AimsTo identify the completeness of documentation of Complementary And Alternative Medicine (CAM) use in hospital medical records of patients before and after an education programme.Full Text Available

2005-02-01

399

Half-trek criterion for generic identifiability of linear structural equation models  

CERN Document Server

A linear structural equation model relates random variables of interest and corresponding Gaussian noise terms via a linear equation system. Each such model can be represented by a mixed graph in which directed edges encode the linear equations, and bidirected edges indicate possible correlations among noise terms. We study parameter identifiability in these models, that is, we ask for conditions that ensure that the edge coefficients and correlations appearing in a linear structural equation model can be uniquely recovered from the covariance matrix of the associated normal distribution. We treat the case of generic identifiability, where unique recovery is possible for almost every choice of parameters. We give a new graphical criterion that is sufficient for generic identifiability. It improves criteria from prior work and does not require the directed part of the graph to be acyclic. We also develop a related necessary ...

2011-01-01

400

HIV prevention for South African youth: which interventions work? A systematic review of current evidence  

UK PubMed Central (United Kingdom)

BackgroundIn South Africa, HIV prevalence among youth aged 15-24 is among the world's highest. Given the urgent need to identify effective HIV prevention approaches, this review...Full Text Available

401

Granite Countertops and Radiation | Radiation Protection | US EPA  

Wastenet

... Top of page Testing Radiation coming from granite countertops results from natural radioactive material in the granite. Identifying the presence and concentration of radioactive elements in granite requires expensive and sophisticated portable instruments or laboratory equipment. These instruments and equipment require proper calibration, and interpretation of ...

402

Genome-Wide Identification and Evolutionary Analysis of the Animal Specific ETS Transcription Factor Family  

UK PubMed Central (United Kingdom)

The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available

403

Genetic architecture of voluntary exercise in an advanced intercross line of mice  

UK PubMed Central (United Kingdom)

Exercise is essential for health, yet the amount, duration, and intensity that individuals engage in are strikingly variable, even under prescription. Our focus was to identify the locations and effects...Full Text Available

2010-07-01

404

Gene-gene and gene-environment interactions: new insights into the prevention, detection and management of coronary artery disease  

UK PubMed Central (United Kingdom)

Despite the recent success of genome-wide association studies (GWASs) in identifying loci consistently associated with coronary artery disease (CAD), a large proportion of the genetic components of...Full Text Available

405

Fast, Scalable, Bayesian Spike Identification for Multi-Electrode Arrays  

UK PubMed Central (United Kingdom)

We present an algorithm to identify individual neural spikes observed on high-density multi-electrode arrays (MEAs). Our method can distinguish large numbers of distinct neural units, even when spikes...Full Text Available

406

Factors governing the periodic activation of supraoptic and paraventricular neurosecretory cells during suckling in the rat.  

UK PubMed Central (United Kingdom)

1. One hundred and thirty-two antidromically identified paraventricular (PV) and supraoptic (SO) neurones were studied during milk ejection evoked by the suckling of the young, in thirty-four lactating...Full Text Available

1975-09-01

407

Expression and purification of a functional human hepatitis B virus polymerase  

UK PubMed Central (United Kingdom)

AIM: To identify a method for efficient large-scale purification of functional hepatitis B virus polymerase (HBV-Pol) without addition of cellular factors.METHODS: Full-length HBV-Pol (843 amino...Full Text Available

2010-12-07

408

Expression and Trans-Specific Polymorphism of Self-Incompatibility RNases in Coffea (Rubiaceae)  

UK PubMed Central (United Kingdom)

Self-incompatibility (SI) is widespread in the angiosperms, but identifying the biochemical components of SI mechanisms has proven to be difficult in most lineages. Coffea (coffee;...Full Text Available

409

Exome sequencing identifies GRIN2A as frequently mutated in melanoma  

UK PubMed Central (United Kingdom)

The incidence of melanoma is increasing more than any other cancer, and knowledge of its genetic alterations is limited. To systematically analyze such alterations, we performed whole-exome...Full Text Available

2011-05-01

410

Evaluation of the OptiMAL Test for Rapid Diagnosis of Plasmodium vivax and Plasmodium falciparum Malaria  

UK PubMed Central (United Kingdom)

The development of rapid and specific diagnostic tests to identify individuals infected with malaria is of paramount importance in efforts to control the severe public health impact of this disease....Full Text Available

1998-01-01

411

Evaluation of Acyl Coenzyme A Oxidase (Aox) Isozyme Function in the n-Alkane-Assimilating Yeast Yarrowia lipolytica  

UK PubMed Central (United Kingdom)

We have identified five acyl coenzyme A (CoA) oxidase isozymes (Aox1 through Aox5) in the n-alkane-assimilating yeast Yarrowia lipolytica, encoded by the POX1...Full Text Available

1999-09-01

412

Evaluating the Involvement of Alternative Sigma Factors SigF and SigG in Clostridium perfringens Sporulation and Enterotoxin Synthesis?  

UK PubMed Central (United Kingdom)

Clostridium perfringens type A food poisoning is the second most commonly identified bacterial food-borne illness. Sporulation contributes to this disease in two ways: (i) most food-poisoning...Full Text Available

2010-10-01

413

Establishment of an Immunoglobulin M Antibody-Forming Cell Response Model for Characterizing Immunotoxicity in Primary Human B Cells  

UK PubMed Central (United Kingdom)

Rodent models have been extensively utilized to identify putative human immunotoxicants; however, even when immunotoxicity is established, uncertainty remains whether the effects are predictive of human...Full Text Available

2009-12-01

414

Energy Performance Contracting for New Buildings  

Wastenet

situ by isolating portions of the building envelope and performing tests .MAXIMUM ALLOWED LOAD ...and shall identify commissioning team members who will perform testing and prepare documentation.The commissioning agent may be

415

Employing Kirkpatrick's Evaluation Framework to Determine the Effectiveness of Health Information Management Courses and Programs  

UK PubMed Central (United Kingdom)

Evaluation of the impact and effectiveness of courses is necessary so that strengths and weaknesses can be identified and improvements made. This article uses Kirkpatrick's evaluation framework to present...Full Text Available

416

Distribution of lead-203 in human peripheral blood in vitro.  

UK PubMed Central (United Kingdom)

In-vitro experiments using 203Pb were performed to identify the lead binding components in human peripheral blood. The distribution of lead in plasma, in the red cell membrane, and within the red cell...Full Text Available

1980-02-01

417

Differential neural contributions to native- and foreign-language talker identification  

UK PubMed Central (United Kingdom)

Humans are remarkably adept at identifying individuals by the sound of their voice, a behavior supported by the nervous system’s ability to integrate information from voice and speech...Full Text Available

2009-12-01

418

Developing IT Infrastructure for Rural Hospitals: A Case Study of Benefits and Challenges of Hospital-to-Hospital Partnerships  

UK PubMed Central (United Kingdom)

This article presents a study identifying benefits and challenges of a novel hospital-to-hospital information technology (IT) outsourcing partnership (HHP). The partnership is an innovative response...Full Text Available

2008-07-01

419

Detection and Identification of Ciprofloxacin-Resistant Yersinia pestis by Denaturing High-Performance Liquid Chromatography  

UK PubMed Central (United Kingdom)

Denaturing high-performance liquid chromatography (DHPLC) has been used extensively to detect genetic variation. We used this method to detect and identify Yersinia pestis KIM5 ciprofloxacin-resistant...Full Text Available

2003-07-01

420

Delineating Bacteriostatic and Bactericidal Targets in Mycobacteria Using IPTG Inducible Antisense Expression  

UK PubMed Central (United Kingdom)

In order to identify novel high value antibacterial targets it is desirable to delineate whether the inactivation of the target enzyme will lead to bacterial death or stasis. This knowledge is particularly...Full Text Available

421

Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulence  

UK PubMed Central (United Kingdom)

The Gram-negative bacterium Francisella tularensis is the causative agent of tularemia. Interest in this zoonotic pathogen has increased due to its classification as a category A agent...Full Text Available

2006-08-22

422

Deep Desulfurization of Diesel Oil and Crude Oils by a Newly Isolated Rhodococcus erythropolis Strain  

UK PubMed Central (United Kingdom)

The soil-isolated strain XP was identified as Rhodococcus erythropolis. R. erythropolis XP could efficiently desulfurize benzonaphthothiophene, a complicated model sulfur compound that...Full Text Available

2006-01-01

423

DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase  

UK PubMed Central (United Kingdom)

CDC7 is an essential gene required for DNA replication in Saccharomyces cerevisiae. Cdc7p homologs have recently been identified in vertebrates, but their role in DNA...Full Text Available

1999-03-16

424

DECOMP: A PDB decomposition tool on the web  

UK PubMed Central (United Kingdom)

The protein databank (PDB) contains high quality structural data for computational structural biology investigations. We have earlier described a fast tool (the decomp_pdb tool) for identifying and...Full Text Available

425

Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies.  

UK PubMed Central (United Kingdom)

The authors have recently identified a new cytokeratin (CK) polypeptide, CK 20, whose expression is almost entirely confined to the gastric and intestinal epithelium, urothelium, and Merkel cells. Seven...Full Text Available

1992-02-01

426

Coryneform bacteria in infectious diseases: clinical and laboratory aspects.  

UK PubMed Central (United Kingdom)

Coryneform isolates from clinical specimens frequently cannot be identified by either reference laboratories or research laboratories. Many of these organisms are skin flora that belong to a large number...Full Text Available

1990-07-01

427

Confirmation of human Campylobacter concisus isolates misidentified as Campylobacter mucosalis and suggestions for improved differentiation between the two species.  

UK PubMed Central (United Kingdom)

A strain from human diarrhea originally identified as Campylobacter mucosalis (NCTC 12408) was examined by using 64 phenotypic characters. The similarity of this strain to 297 isolates of Campylobacter,...Full Text Available

1994-09-01

428

Comparison of Different Measures of Urinary Protein Excretion for Prediction of Renal Events  

UK PubMed Central (United Kingdom)

There are many methods to screen for abnormal amounts of proteinuria to identify patients at risk for progression of renal disease, but which method best predicts renal risk is unknown. Here, we analyzed...Full Text Available

2010-08-01

429

Comparative analysis of cis-regulation following stroke and seizures in subspaces of conserved eigensystems  

UK PubMed Central (United Kingdom)

BackgroundIt is often desirable to separate effects of different regulators on gene expression, or to identify effects of the same regulator across several systems. Here, we focus...Full Text Available

430

Coal to liquids technology (Overview - Research)  

Wastenet

... After completing a review into direct coal liquefaction research carried out in Australia and internationally, CSIRO has identified potential new science and technology developments that may improve the cost and viability of CTL in a greenhouse gas-constrained environment. We are conducting research to: determine the optimum ...

431

Clinical Correlates to Laboratory Measures for use in Non-Contact Anterior Cruciate Ligament Injury Risk Prediction Algorithm  

UK PubMed Central (United Kingdom)

BackgroundProspective measures of high knee abduction moment during landing identify female athletes at high risk for non-contact anterior cruciate ligament injury....Full Text Available

2010-08-01

432

Climate Change, Genetics or Human Choice: Why Were the Shells of Mankind's Earliest Ornament Larger in the Pleistocene Than in the Holocene?  

UK PubMed Central (United Kingdom)

BackgroundThe southern African tick shell, Nassarius kraussianus (Dunker, 1846), has been identified as being the earliest known ornamental object used by human...Full Text Available

433

Characterization of Two Unique Cholesterol-Rich Lipid Particles Isolated from Human Atherosclerotic Lesions  

UK PubMed Central (United Kingdom)

The authors' laboratory, using histochemicalmethods, previously identified two types of cholesterol-containing lipid particles in the extracellular spaces of human atherosclerotic lesions, one particle...Full Text Available

1990-01-01

434

Chaotic system of two-phase flow in a small, horizontal, rectangular channel.  

Science.gov (United States)

Various measurement tools that are used in chaos theory were applied to analyze two-phase pressure signals with the objective of identifying and interpreting flow pattern transitions for two-phase flows in a small, horizontal rectangular channel. These me...

1995-01-01

435

Central gating of fly optomotor response  

UK PubMed Central (United Kingdom)

We study the integration of multisensory and central input at the level of an identified fly motoneuron, the ventral cervical nerve motoneuron (VCNM) cell, which controls head movements of the animal....Full Text Available

2010-11-16

436

Carpal Tunnel Syndrome and Peripheral Polyneuropathy in Patients with End Stage Kidney Disease  

UK PubMed Central (United Kingdom)

This study was designed to identify the causes of the development of carpal tunnel syndrome (CTS) associated with end stage kidney disease (ESKD). A total of 112 patients with ESKD, 64 on hemodialysis...Full Text Available

2011-09-01

437

Cancer in young people in the north of England, 1968-85: analysis by census wards.  

UK PubMed Central (United Kingdom)

OBJECTIVE--To determine whether the seeming excess of childhood leukaemia and lymphoma identified in Seascale, Cumbria, UK, remains unusual when put into a wider context. DESIGN--Analysis of cancer...Full Text Available

1993-04-01

438

CD133 Positive Embryonal Rhabdomyosarcoma Stem-Like Cell Population Is Enriched in Rhabdospheres  

UK PubMed Central (United Kingdom)

Cancer stem cells (CSCs) have been identified in a number of solid tumors, but not yet in rhabdomyosarcoma (RMS), the most frequently occurring soft tissue tumor in childhood. Hence, the aim of this...Full Text Available

439

Burnout sensitivity of power MOSFETs operating in a switching converter  

International Nuclear Information System (INIS)

Heavy ion tests of a switching converter using power MOSFETs have allowed us to identify the main parameters which affect the burnout sensitivity of these components. The differences between static and dynamic conditions are clarified in this paper. (author). 7 refs., 16 figs., 3 tabs.

440

Brain transcriptomic analysis in paper wasps identifies genes associated with behaviour across social insect lineages  

UK PubMed Central (United Kingdom)

Comparative sociogenomics has the potential to provide important insights into how social behaviour evolved. We examined brain gene expression profiles of the primitively eusocial wasp Polistes...Full Text Available

2010-07-22

441

Boron Tolerance in Barley Is Mediated by Efflux of Boron from the Roots1  

UK PubMed Central (United Kingdom)

Many plants are known to reduce the toxic effects of high soil boron (B) by reducing uptake of B, but no mechanism for limiting uptake has previously been identified. The B-tolerant cultivar of barley...Full Text Available

2004-10-01

442

Biomarkers Signal Contaminant Effects on the Organs of English Sole (Parophrys vetulus) from Puget Sound  

UK PubMed Central (United Kingdom)

Fish living in contaminated environments accumulate toxic chemicals in their tissues. Biomarkers are needed to identify the resulting health effects, particularly focusing on early changes at a subcellular...Full Text Available

2006-06-01

443

Biochemical analysis of PIFTC3, the Trypanosoma brucei ortholog of nematode DYF-13, reveals interactions with established and putative intraflagellar transport components  

UK PubMed Central (United Kingdom)

DYF-13, originally identified in C. elegans within a collection of dye-filling chemosensory mutants, is one of several proteins that have been classified as putatively involved...Full Text Available

2010-10-01

444

Biobank resources for future patient care: developments, principles and concepts  

UK PubMed Central (United Kingdom)

The aim of the overview is to give a perspective of global biobank development is given in a view of positioning biobanking as a key resource for healthcare to identify new potential markers that can...Full Text Available

445

Bacterial response to siderophore and quorum-sensing chemical signals in the seawater microbial community  

UK PubMed Central (United Kingdom)

BackgroundOceans are iron-deficient and nutrient-poor environments. These conditions impart limitations on our understanding of and our ability to identify microorganisms from the...Full Text Available

446

Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells  

UK PubMed Central (United Kingdom)

The CD1 family of proteins binds self and foreign glycolipids for presentation to CD1-restricted T cells. To identify previously uncharacterized active CD1 ligands, especially those of microbial origin,...Full Text Available

2005-02-01

447

Bacterial Competition for Human Nasal Cavity Colonization: Role of Staphylococcal agr Alleles  

UK PubMed Central (United Kingdom)

We examined the bacterial aerobic nasal flora of 216 healthy volunteers to identify potential competitive interactions among different species, with special emphasis on the influence of staphylococcal...Full Text Available

2003-01-01

448

Autophosphorylation Within the Atg1 Activation Loop Is Required for Both Kinase Activity and the Induction of Autophagy in Saccharomyces cerevisiae  

UK PubMed Central (United Kingdom)

Autophagy is an evolutionarily conserved degradative pathway that has been implicated in a number of physiological events important for human health. This process was originally identified as a response...Full Text Available

2010-07-01

449

Associations between dairy production indices and lipoarabinomannan enzyme-immunoassay results for paratuberculosis.  

UK PubMed Central (United Kingdom)

Data from an epidemiological study in Ontario, involving 304 dairy herds, were used to identify associations between selected production indices and lipoarabinomannan antigen serological test results...Full Text Available

1991-10-01

450

Association of serum markers with improvement in clinical response measures after treatment with golimumab in patients with active rheumatoid arthritis despite receiving methotrexate: results from the GO-FORWARD study  

UK PubMed Central (United Kingdom)

IntroductionThe goal of this study was to identify serum markers that are modulated by treatment with golimumab with or without methotrexate (MTX) and are associated with clinical...Full Text Available

2010-01-01

451

Army energy plan. Technical report  

Science.gov (United States)

The Plan identifies the Army's organization, goals, objectives, and policies with respect to energy. It projects energy consumption and costs to the year 2000 and summarizes the programs required to support the long range goals. A summary of current and needed energy related legislation is included. (Author)

1978-02-24

452

Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-?B-dependent iNOS and proinflammatory cytokines production  

UK PubMed Central (United Kingdom)

Background and purpose:Glycyrrhizae radix has been widely used as a cytoprotective, plant-derived medicine. We have identified a flavanoid, liquiritigenin, as an...Full Text Available

2008-05-01

453

Anti-beta-endorphin immunoglobulin G in humans.  

UK PubMed Central (United Kingdom)

Human IgG specific for beta-endorphin was identified by enzyme-linked immunoabsorbent assay and isolated by affinity chromatography. From a sample of 27 subjects, three individuals with major depression...Full Text Available

1986-11-01

454

Antagonistic Gcn5-Hda1 interactions revealed by mutations to the Anaphase Promoting Complex in yeast  

UK PubMed Central (United Kingdom)

BackgroundHistone post-translational modifications are critical for gene expression and cell viability. A broad spectrum of histone lysine residues have been identified in yeast...Full Text Available

455

Analysis of target cell susceptibility as a basis for the development of a chemoprotective strategy against benzene-induced hematotoxicities.  

UK PubMed Central (United Kingdom)

A goal of our research is to identify biochemical factors that underlie the susceptibility of bone marrow cell populations to benzene metabolites so as to develop a mechanistically based chemoprotective...Full Text Available

1996-12-01

456

Analysis of Failed Spinal Cord Stimulation Trials in the Treatment of Intractable Chronic Pain  

UK PubMed Central (United Kingdom)

ObjectiveThe purpose of this study is to identify the factors affecting the failure of trials (<50% pain reduction in pain for trial period) to improve success rate of spinal...Full Text Available

2008-02-01

457

An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer  

UK PubMed Central (United Kingdom)

BackgroundGenomics has substantially changed our approach to cancer research. Gene expression profiling, for example, has been utilized to delineate subtypes of cancer, and facilitated...Full Text Available

458

An Intrinsic Neuronal Oscillator Underlies Dopaminergic Neuron Bursting  

UK PubMed Central (United Kingdom)

Dopaminergic neurons of the ventral midbrain fire high frequency bursts when animals are presented with unexpected rewards, or stimuli that predict reward. To identify the afferents that can...Full Text Available

2009-12-16

459

Amazon.com: Customer Reviews: Womenomics: Write Your Own Rules for Success  

Wastenet

...Own Rules for Success (Hardcover) The authors have rightly identified that there is a growing demand for, trend towards, and interest in guidance for creating flexible working arrangements. However, for $27.99, you can secure more concrete advice on reaching your \\

460

Alcohol and the fetus in the west of Scotland.  

UK PubMed Central (United Kingdom)

Forty children with the fetal alcohol syndrome were identified in the west of Scotland. All were growth retarded and had abnormal facial features, and all those who were tested were found to have neurological...Full Text Available

1983-07-02

461

Accuracy of Contacts Calculated from 3D Images of Occlusal Surfaces  

UK PubMed Central (United Kingdom)

ObjectiveCompare occlusal contacts calculated from 3D virtual models created from clinical records to contacts identified clinically using shimstock and transillumination.Full Text Available

2007-06-01

462

ATG12 Conjugation to ATG3 Regulates Mitochondrial Homeostasis and Cell Death  

UK PubMed Central (United Kingdom)

SUMMARYATG12, an ubiquitin-like modifier required for macroautophagy, has a single known conjugation target, another autophagy regulator called ATG5. Here, we identify ATG3 as...Full Text Available

2010-08-20

463

A polyacetylene compound from herbal medicine regulates genes associated with thrombosis in endothelial cells  

UK PubMed Central (United Kingdom)

From Toki-shakuyaku-san, an herbal formulation for “cleansing stagnated blood,” a key gene regulatory compound was purified and identified through a screening based on DNA microarray...Full Text Available

2007-12-15

464

A new VCAN/versican splice acceptor site mutation in a French Wagner family associated with vascular and inflammatory ocular features  

UK PubMed Central (United Kingdom)

PurposeTo detail the highly variable ocular phenotypes of a French family affected with an autosomal dominantly inherited vitreoretinopathy and to identify the disease gene.MethodsSixteen...Full Text Available

465

A Web-based Interface for Communication of Data between the Clinical and Research Environments without Revealing Identifying Information  

UK PubMed Central (United Kingdom)

Recent health care policies and regulations have impacted the manner in which patient data – especially protected health information (PHI) – are handled in both the clinical...Full Text Available

2007-06-01

466

A Novel Mouse Model of Red Blood Cell Storage and Post-Transfusion in Vivo Survival  

UK PubMed Central (United Kingdom)

BackgroundStorage of RBCs is necessary for an adequate blood supply. However, reports have identified potential negative sequelae of transfusing stored RBCs. An animal...Full Text Available

2009-08-01

467

A NEW APPROACH TO UNDERSTANDING THE MOLECULAR MECHANISMS THROUGH WHICH ESTROGENS AFFECT COGNITION  

UK PubMed Central (United Kingdom)

Traditional approaches to the study of hormones and cognition have been primarily observational or correlational in nature. Because this work does not permit causal relationships to be identified,...Full Text Available

2010-10-01

468

A Humanin Derivative Reduces Amyloid Beta Accumulation and Ameliorates Memory Deficit in Triple Transgenic Mice  

UK PubMed Central (United Kingdom)

Humanin (HN), a 24-residue peptide, was identified as a novel neuroprotective factor and shows anti-cell death activity against a wide spectrum of Alzheimer's disease (AD)-related cytotoxicities, including...Full Text Available

469

A Hemorrhagic Factor (Apicidin) Produced by Toxic Fusarium Isolates from Soybean Seeds  

UK PubMed Central (United Kingdom)

Fifty-two isolates of Fusarium species were obtained from soybean seeds from various parts of Korea and identified as Fusarium oxysporum, F. moniliforme,...Full Text Available

1999-01-01

470

A Disordered Eating Response Team's Effect on Nutrition Practices in College Athletes  

UK PubMed Central (United Kingdom)

The disordered eating response team developed a protocol for assessment and intervention for athletes who are identified as at risk for disordered eating. Team members included the team physician,...Full Text Available

1995-10-01

471

A Cytogenetic Abnormality and Rare Coding Variants Identify ABCA13 as a Candidate Gene in Schizophrenia, Bipolar Disorder, and Depression  

UK PubMed Central (United Kingdom)

Schizophrenia and bipolar disorder are leading causes of morbidity across all populations, with heritability estimates of ∼80% indicating a substantial genetic component. Population genetics...Full Text Available

2009-12-11

472

A Computer Vision System for Automated Grading of Rough Hardwood Lumber Using a Knowledge-Based Approach  

Science.gov (United States)

... in this paper is aimed at developing a computer vision system that will be used to automatically grade rough hardwood lumber. The purpose of the computer vision system is to locate and identify grading def...

473

A Comparison of intra-oral digital imaging modalities: Charged Couple Device versus Storage Phosphor Plate  

UK PubMed Central (United Kingdom)

BackgroundThis in vitro study was conducted to compare the accuracy of two digital image receptors in identifying the location of tip of a fine endodontic file and radiographic apex...Full Text Available

2010-11-01

474

45 CFR 1175.110 - Self-evaluation.  

Science.gov (United States)

...shall, until three years following the completion of the self-evaluation, maintain on file and make available for public inspections: (1) A description of areas examined and any problems identified, and (2) A description of any...

2010-10-01

475

1H-NMR-Based Metabolomic Profiling of CSF in Early Amyotrophic Lateral Sclerosis  

UK PubMed Central (United Kingdom)

BackgroundPathophysiological mechanisms involved in amyotrophic lateral sclerosis (ALS) are complex and none has identified reliable markers useful in routine patient evaluation....Full Text Available

476

Waste Sampling and Characterization Facility (WSCF). Maintenance Implementation Plan  

Energy Technology Data Exchange (ETDEWEB)

This Maintenance Implementation Plan has been developed for maintenance functions associated with the Waste Sampling and Characterization Facility (WSCF). This plan is developed from the guidelines presented by Department of Energy (DOE) Order 4330.4A, Maintenance Management Program (DOE 1990), Chapter II. The objective of this plan is to provide baseline information for establishing and identifying WHC conformance programs and policies applicable to implementation of DOE order 4330.4A guidelines. In addition, this maintenance plan identifies the actions necessary to develop a cost-effective and efficient maintenance program at WSCF.

1993-07-01

477

Theory and method for selection of power system stabilizer location  

Energy Technology Data Exchange (ETDEWEB)

A new approach for the selection of best PSS locations in multimachine power systems is proposed in this paper. Study shows that the right-eigenvector measures the activity of state variables and the left-eigenvector measures the control effect of control signals. Based on the right and left eigenvector the concept of sensitivity of PSS effect (SPE) is presented and used to identify the best PSS locations. The proposed method is used to identify the best PSS location in a 13-machine system to increase the damping of an interarea mode. The time-domain simulation results confirm that the prediction of best PSS location by SPE method is correct and accurate.

1991-03-01

478

RAPID DAMAGE ASSESSMENT FROM HIGH RESOLUTION IMAGERY  

Energy Technology Data Exchange (ETDEWEB)

Disaster impact modeling and analysis uses huge volumes of image data that are produced immediately following a natural or an anthropogenic disaster event. Rapid damage assessment is the key to time critical decision support in disaster management to better utilize available response resources and accelerate recovery and relief efforts. But exploiting huge volumes of high resolution image data for identifying damaged areas with robust consistency in near real time is a challenging task. In this paper, we present an automated image analysis technique to identify areas of structural damage from high resolution optical satellite data using features based on image content.

2008-07-01

479

Patient isolation in chronic benign pain.  

Science.gov (United States)

Over the years, nurses, doctors and scientists have sought ways of assessing the impact of pain on patients. While many of the instruments devised have been extremely useful in identifying the nature and intensity of pain, defining the effect it has on people's lives and perceptions has proved much more problematic. Based on the work she carried out with patients suffering from chronic benign pain, Karen Rose explores one aspect of these effects--the feeling of isolation. By using a four-step anthropological approach to identify the impact of pain, she argues, nurses can arrive at a realistic and accurate assessment of how patients are coping. PMID:7947167

480

Opportunities for coal liquefaction research in British Columbia  

Energy Technology Data Exchange (ETDEWEB)

This paper presents the results of a study commissioned by the British Columbia Science Council to identify opportunities for liquefaction of B.C. coals and to recommend effective approaches to the development of a research program on coal conversion. Contains reviews of British Columbia coal resources to identify prospective candidates for conversion to liquid fuels; of the state of the art in the various processes for the conversion of coal to liquid fuels with particular emphasis on those processes most relevant to British Columbia applications; and of research opportunities in British Columbia for the development of coal liquefaction technology. (16 refs.)

1980-05-01

481

Lack of awareness of symptoms in people with dementia: the structural and functional basis  

British Library Electronic Table of Contents (United Kingdom)

AbstractObjective To review studies investigating the brain correlates of unawareness of cognitive and behavioural symptoms in people with dementia. Design A detailed search of the literature was conducted to include all the peer-reviewed studies published in English aimed at identifying the structural or functional brain correspondents of unawareness in dementia patients. Their results were interpreted in relation to the methodological differences in terms of type of dementia studied, the protocol adopted to measure lack of awareness, the imaging techniques employed, the experimental designs and statistical analyses performed. Results Eighteen studies undertaken to explore the functional and structural correlates of unawareness of cognitive symptoms in dementia were identified. Although t...

2011-01-01

482

How the Energy and Water Development Appropriations Act of 1993 has impacted the constitutional dynamics of federal wetlands delineation and regulation  

Energy Technology Data Exchange (ETDEWEB)

A reliable source of specific criteria for recognizing a wetland, as defined for regulatory purposes would be valuable. In 1987 the Army Corps of Engineers developed a technical manual for identifying wetlands (1987 Wetlands Manual). An interagency manual (1989 Wetlands Manual) was later developed. This manual has been used to identify wetlands according to three evidentiary factors: vegetation, hydrology, and soil. This paper addresses the development of criteria to delineate wetlands, and describes some of the logic used by federal courts to uphold the limited constitutional use of the 1989 Wetlands Manual.

1995-12-31

483

Hazard Evaluation for the Saltwell Chempump and a Saltwell Centrifugal Pump Design using Service Water for Lubrication and Cooling  

Energy Technology Data Exchange (ETDEWEB)

This report documents results of a preliminary hazard analysis (PHA) covering the existing Crane Chempump and the new salt well pumping design. Three hazardous conditions were identified for the Chempump and ten hazardous conditions were identified for the new salt well pump design. This report also presents the results of the control decision/allocation process. A backflow preventer and associated limiting condition for operation were assigned to one hazardous condition with the new design.

2000-11-16

484

Effect of the size of an artificial neural network used as pattern identifier  

Energy Technology Data Exchange (ETDEWEB)

A novel way to extract relevant parameters associated with the outgoing ions from nuclear reactions, obtained by digitizing the signals provided by a Bragg curve spectrometer (BCS) is presented. This allowed the implementation of a more thorough pulse-shape analysis. Due to the complexity of this task, it was required to take advantage of new and more powerful computational paradigms. This was fulfilled using a back-propagation artificial neural network (ANN) as a pattern identifier. Over training of ANNs is a common problem during the training stage. In the performance of the ANN there is a compromise between its size and the size of the training set. Here, this effect will be illustrated in relation to the problem of Bragg Curve (BC) identification. (Author)

2003-07-01

485

Cost-time management: A powerful tool in a new application - cleaning up the weapons complex  

International Nuclear Information System (INIS)

Westinghouse Electric Corporation is aggressively applying cost-time management to bolster timely, cost-effective cleanup and waste management activities at sites it manages for the U.S. Department of Energy (DOE). Cost-time management is a diagnostic technique which is applicable to virtually any process. It identifies opportunities to reduce cycle-times and costs. When applied to cleanup and waste management at DOE facilities, cost-time profile analysis helps identify actions to improve productivity and quality. Moreover, by reducing cycle-times and costs, it achieves significant savings to taxpayers. (author)

1992-03-01

486

Competencies of Employment Specialists for Effective Job Development  

British Library Electronic Table of Contents (United Kingdom)

A scant body of literature addresses competencies needed for successful job development. This study aimed to identify competencies needed for this role. In this analysis, we observed employment specialists identified as successful in helping consumers obtain employment perform job development duties. We supplemented observations with interviews. Employment specialists possessed competencies in six domains: time management, advocacy, building partnerships with consumers, working as part of a team, face-to-face communication, and networking. The conceptual framework derived from this study can inform supported employment supervisors and researchers about the competencies that can strengthen supported employment teams.

2011-01-01

487

Yeast allosteric chorismate mutase is locked in the activated state by a single amino acid substitution  

International Nuclear Information System (INIS)

Chorismate mutase, a branch-point enzyme in the aromatic amino acid pathway of Saccharomyces cerevisiae, and also a mutant chorismate mutase with a single amino acid substitution in the C-terminal part of the protein have been purified approximately 20-fold and 64-fold from overproducing strains, respectively. The wild-type enzyme is activated by tryptophan and subject to feedback inhibition by tyrosine, whereas the mutant enzyme does not respond to activation by tryptophan nor inhibition by tyrosine. Both enzymes are dimers consisting of two identical subunits of M_r 30,000, each one capable of binding one substrate and one activator molecule. Each subunit of the wild-type enzyme also binds one inhibitor molecule, whereas the mutant enzyme lost this ability. The enzyme reaction was observed by "1H NMR and shows a direct and irreversible conversion of chorismate to prephenate without the accumulation of any enzyme-free intermediates. The kinetic data of the ...

488

Validation of immune function testing during a 4-week oral toxicity study with FK506.  

Science.gov (United States)

Assessment of the immune system's capability to respond to antigens with the generation of specific antibodies, whilst under the influence of a test article, is required in toxicity tests according to the European guideline for repeated dose toxicity testing of medicinal products. The purpose of this study in rats was to validate methodology for the determination of Keyhole Limpet Haemocyanin (KLH)-specific antibodies under the influence of an immunologically active compound. The immunosuppressant FK506, commercially available as Prograf, was administered orally (gavage) to five rats per sex per group at dosages of 0.5mg/kg per day or 3mg/kg per day, for a period of 4 weeks. On days 14 and 22, KLH was administered subcutaneously, with an adjuvant (AluGel), to the two treated groups and a control (i.e. without FK506 treatment) approximately 1h following administration of FK506. Terminal investigations included haematology parameters, titration of KLH-specific ...

2004-04-01

489

Pyridoxine dependent epilepsy and antiquitin deficiency Clinical and molecular characteristics and recommendations for diagnosis, treatment and follow-up.  

Science.gov (United States)

Antiquitin (ATQ) deficiency is the main cause of pyridoxine dependent epilepsy characterized by early onset epileptic encephalopathy responsive to large dosages of pyridoxine. Despite seizure control most patients have intellectual disability. Folinic acid responsive seizures (FARS) are genetically identical to ATQ deficiency. ATQ functions as an aldehyde dehydrogenase (ALDH7A1) in the lysine degradation pathway. Its deficiency results in accumulation of ?-aminoadipic semialdehyde (AASA), piperideine-6-carboxylate (P6C) and pipecolic acid, which serve as diagnostic markers in urine, plasma, and CSF. To interrupt seizures a dose of 100mg of pyridoxine-HCl is given intravenously, or orally/enterally with 30mg/kg/day. First administration may result in respiratory arrest in responders, and thus treatment should be performed with support of respiratory management. To make sure that late and masked response is not missed, treatment with oral/enteral pyridoxine should be ...

2011-05-24

490

Proliferation and differentiation of brown adipocytes from interstitial cells during cold acclimation  

Energy Technology Data Exchange (ETDEWEB)

The mechanisms of brown adipocyte proliferation and differentiation during cold acclimation (and/or adaptation to hyperphagia) have been studied by quantitative photonic radioautography. (/sup 3/H)thymidine was injected to warm-acclimated (25/sup 0/C) rats and to animals exposed to 5/sup 0/C for 2 days. Samples of interscapular brown adipose tissue were collected for quantitative analysis of mitotic frequencies at various periods of time (4 h-15 days) after the injection of (/sup 3/H)thymidine, the rats being maintained at the temperatures to which they were initially exposed. It was found that cold exposure for 2 days markedly enhanced mitotic activity in endothelial cells, interstitial cells, and brown preadipocytes rather than in fully differentiated brown adipocytes. The total tissue labeling index (percent of labeled nuclei) increased approx.70 times over control values. The authors now report that cellular labeling progressively increased in mature brown adipocytes during cold ...

1986-06-01

491

Performance of SPNDs used in control and safety systems  

International Nuclear Information System (INIS)

Large sized reactor such as 540 MWe Pressurised Heavy Water Reactor (PHWR) requires continuous in core monitoring of local flux in order to provide effective control and protection. About 198 self powered neutron detectors (SPNDs) of the straight individually replaceable type are distributed in the reactor core. For purposes of reactor regulation, 42 prompt responding cobalt SPNDs called zone control detectors (ZCDs) are housed in vertical flux units (VFUs) and these are uniformly distributed in 14 power zones. The in core detectors used for spatial control by ZCCs do not accurately represent average zone power as they sense the flux over a small volume. Flux mapping system (FMS) comprising of 102 vanadium SPNDs in 26 VFUs, provide accurate measure of neutron flux, even though they have slow response to change in neutron flux levels. For reactor protection system-1 (RPS-1), 36 cobalt SPNDs are placed in VFUs and become part of core overpower protection system-1 ...

2006-11-13

492

Molecular mechanisms of the epithelial transport of toxic metal ions, particularly mercury, cadmium, lead, arsenic, zinc, and copper. Progress report, January 1, 1979-December 31, 1979  

International Nuclear Information System (INIS)

The mechanism of lead transport is presented, and especially the particular similarities or dissimilarities between lead and calcium in this process. The absorption of these metals was determined cockerels, raised on a commercial diet or on a specified diet, using in vivo ligated loop procedure. The dose administered into the loop contained 0.5 #mu#Ci "2"0"3Pb (and/or 0.1 #mu#Ci "4"7Ca), and 0.01 mM lead acetate (and/or mM CaCl_2) in 0.5 ml 0.15 M NaCl,pH 6.5. It was shown that lead is rapidly taken up by the mucosal tissue, and slowly transferred into the body, whereas less calcium is retained by the tissue and the transfer of calcium is many times as effective as that for lead. They appear to respond in a similar manner to a low calcium intake and vitamin D treatment. Increasing luminal stable lead concentration significantly reduced the percentage of radiolead significantly reduced the percentage of radiolead absorbed, but did not affect the absorption of ...

493

Influence of lipolysis on the mobilization of 2,4,5,2'4',5'-hexachlorobiphenyl from adipocytes in vitro  

Energy Technology Data Exchange (ETDEWEB)

Epididymal adipocytes, isolated from rats pretreated with (/sup 14/C)-2,4,5,2',4',5'-hexachlorobiphenyl (6-CB), were utilized to examine the relationship between the mobilization of lipid and 6-CB and to determine whether 6-CB was differentially associated with subcellular organelles over time as has been demonstrated for newly synthesized lipid. Lipolysis, depleted approximately 1% of total cellular triacylglycerols (TG) regardless of time from treatment with 6-CB. The percentage of cellular 6-CB released from adipocytes to incubation buffer infranatants was not correlated with the magnitude of lipolysis produced over the 50-min incubation period; nor was the percentage of 6-CB released to the buffers correlated with the length of the incubation period, regardless of the presence of ISO. Although adipocytes responded similarly to lipolytic stimuli independent of time (days) since 6-CB treatment, significant decreases were found in the ...

1987-01-01

494

Experiences with the operation of a battery energy storage plant for frequency and output control and provision of immediate reserve capacities; Erfahrungen mit Betrieb einer Batteriespeicheranlage zur Frequenz-Leistungs-Regelung und Bereitstellung von Sofortreserveleistung  

Energy Technology Data Exchange (ETDEWEB)

In 1986, following comprehensive preliminary studies, a 17 MW battery energy storage plant was set up in the insular power supply system of Berlin (West) for the purpose of frequency and output control and provision of immediate reserve capacities. The present paper reports on the initial task, and the dimensioning and construction of this large-scale demonstration as well as the costs entailed in this. It also relates the experiences gained with the operation of the battery energy storage plant in its function as a fast-responding control unit and gives an account of its economic efficiency. Recent studies on the economic efficiency of the plant in conditions as they exist in the present interconnected power supply system are presented. Finally the author reports on the experiences gained with individual plant components, i.e., battery, battery periphery, and power converter and quantifies the cost of plant operation, maintenance, and servicing. (orig./HW) ...

1996-12-31

495

Enhancement of efficacy of process water monitors in detecting heavy water leak in steam generator blow down lines  

International Nuclear Information System (INIS)

The Steam Generator (SG) serves as an interface between primary and secondary cycle in Pressurized Heavy Water Reactor (PHWR). Failure of steam generator tubes result in leaking of active heavy water in the secondary closed loop. In Tarapur Atomic Power Station-3 and 4 (TAPS- 3 and 4), Scintillator detectors are provided to detect on line heavy water leakages in SG and moderator heat exchangers by monitoring Nitrogen-16 (16N) and Oxygen-19 (19O) activities. Efficacy of detection of these activities at designed detector position on SG blow down line in presence of background radiation field is analysed theoretically. The count rate of 19O and 16N estimated at the detector position inside Reactor Building (RB) shows that detectors only respond to very high leak rates due to presence of high ambient radiation level even though sensitivity is appreciably good. For detector position in RB in the accessible areas and out side the RE containment, the travel time for the ...

2006-11-13

496

Development of operators' mental model acquisition system (2). Integration of knowledge representation about normal and abnormal plant states  

Energy Technology Data Exchange (ETDEWEB)

This report discusses a representation scheme of device failures anticipated in nuclear power plant, to describe related knowledge in a computer software. Coping ability covering a wide range of physical events is desired in plant operators and maintenance staffs, but it is impractical to give them a set of experience to cover the all possible events in the education/training curriculum. However, in case that their knowledge of plant design and of generally-known physical principles are enforced, their ability of cause identification and of appropriate responding actions against inexperienced events are expected to be enhanced, by combining the basic engineering and physical knowledge. Most of the anomalies anticipated in nuclear power plants are initiated as an incipient failure in some auxiliary equipment initially affecting only within the relative subsystem and hiding from the central control room, and then are propagated to deviate process parameters in the ...

1999-03-01

497

Collaborative and situated learning on the web ? how can teacher education theoretically and practically respond to changing demands and roles of teachers? : A Research based on case studies of online second language learning in ?communities of practice?  

DEFF Research Database (Denmark)

The background for this paper is a growing interest during the past decade in Denmark in the concepts of ?situated learning?, ?social theory of learning? and ?learning in communities of practice? developed by the American social anthropologist Jean Lave and the Californian Research Scientist Etienne Wenger. The work by Jean Lave from 1988 (Lave, 1988) based on anthropological field studies in Brazil and Liberia as well as later works by Lave & Wenger (Lave and Wenger, 1991; Chaiklin and Lave, 1993; Wenger, 1998; Wenger, McDermott, R. and W. Snyder, 2002) on situated learning and social learning theory have provoked considerable response in anthropological studies, in learning theories as well asin considerations about practical implementation of concepts like ?lifelong learning? in Denmark in recent decades. The European concept of ?lifelong learning? has had a big impact on educational thinking, including teacher education. In addition to this, IT has been playing a continuously ...

2006-01-01

498

Analysis of efficacy of process water monitors in detecting heavy water leak in steam generator blow down lines  

International Nuclear Information System (INIS)

The Steam Generator (SG) serves as an interface between primary and secondary cycle in Pressurized Heavy Water Reactor (PHWR). Failure of steam generator tubes result in leaking of active heavy water in the secondary closed loop. In Tarapur Atomic Power Station-3 and 4 (TAPS- 3 and 4), Scintillator detectors are provided to detect on line heavy water leakages in SG and moderator heat exchangers by monitoring Nitrogen-16 ("1"6N) and Oxygen-19 ("1"90) activities. Efficacy of detection of these activities at designed detector position on SG blow down line in presence of background radiation field is analysed theoretically. The count rate of "1"9O and "1"6N estimated at the detector position inside Reactor Building (RB) shows that detectors only respond to very high leak rates due to presence of high background even though sensitivity is appreciably good. For detector position out side the RB containment, the travel time for the feed water becomes very long resulting ...

2005-11-23