... Science: London, 1987; p. 237; (b) Ratner, MA; Shriver, D. F. Chem. ... 11. Lofton, EP; Thackeray, JW; Wrighton, MS J. ... (1) Dr. Harold H. Singerman (1) ...
We report the identification and characterization of a new Drosophila clock-regulated gene, takeout (to). to is a member of a novel...Full Text Available
Most codon indices used today are based on highly biased nonrandom usage of codons in coding regions. The background of a coding or noncoding DNA sequence, however, is fairly random, and can be characterized...Full Text Available
The adhesion of microorganisms onto materials surface mediated by extracellular polymeric substances (EPS) lead to an important modification of the metal-solution interface. The requirement of modern civilization with the heightened sense of environmental responsibilities and quality of life can be met by using some eco-friendly microbiocides with different spectra of activity. Some N{sub 2}O{sub 2} donor Schiff base compounds were synthesized and characterized by IR, NMR and ESR spectroscopy. These compounds were found effective in controlling the growth of biofilm of E. coli, Pseudomonas fluorescens and Thiobacillus thiooxidans on copper surface. The optimum concentration of these compounds are in the range of 1--10 ppm. Various electrochemical, microbiological and surface-analytical techniques were used to monitor the biofilm in the presence of microbiocides.
Previous studies have been conducted in gene expression profiling to identify groups of genes that characterize the colorectal carcinoma disease. Despite the success of previous attempts to identify...Full Text Available
ObjectivesMild Cognitive Impairment (MCI) case-finding criteria have low specificity in general population studies. The present study retrospectively identifies cases...Full Text Available
Environmental chemicals that function as estrogens have been suggested to be associated with an increase in disease and dysfunctions in animals and humans. To characterize chemicals that may act as...Full Text Available
Supercoiled double-stranded DNA molecules (plasmids) were isolated from plants infected with three laboratory strains of western aster yellows mycoplasma-like organism (AY-MLO) by using cesium chloride-ethidium...Full Text Available
Bacillus thuringiensis subsp. israelensis, which is used worldwide to control Aedes aegypti larvae, produces Cry11Aa and other toxins during...Full Text Available
BackgroundIn recent years, the sea anemone Nematostella vectensis has emerged as a critical model organism for comparative genomics and developmental biology. Although...Full Text Available
BackgroundIn chordates, retinoid metabolism is an important target of short-chain dehydrogenases/reductases (SDRs). It is not known whether SDRs play a role in retinoid...Full Text Available
BackgroundSchistosomiasis japonica remains a major public health problem in China. Its pathogen, Schistosoma japonicum has a complex life cycle and a unique repertoire...Full Text Available
AbstractMultiple HIV-1 subtypes and circulating recombinant forms (CRFs) are known to cocirculate in Africa. In West Africa, the high prevalence of CRF02_AG, and cocirculation of subtype...Full Text Available
Cryptococcus neoformans is a pathogenic yeast that often causes devastating meningoencephalitis in immunocompromised individuals. We have previously identified the C. neoformans...Full Text Available
Studies continued on organic tracers for use as hydrologic tracers as part of the Yucca Mountain Site Characterization project. This subject report for the quarter 01/01/93 through 03/31/93 discusses the following issues: project organization and responsibilities; quality assurance program; design control; procurement document control; instructions, procedures, and drawings; document control; control of purchased items and services; identification and control of items; control of processes; inspection; test control; control of measuring and test equipment; handling, storage, and shipping; inspection, test, and operating status; control of nonconforming items and conditions; corrective action; quality assurance records; audits; software quality assurance; and scientific investigation.
The primary objective of this study was to identify, characterize, and map the wetlands in the Bear Creek watershed. A preliminary wetland categorization system based on the Cowardin classification system (Cowardin et al. 1979) with additional site-specific topographic, vegetation, and disturbance characteristic modifiers was developed to characterize the type of wetlands that exist in the Bear Creek watershed. An additional objective was to detect possible relationships among site soils, hydrology, and the occurrence of wetlands in the watershed through a comparison of existing data with the field survey. Research needs are discussed in the context of wetland functions and values and regulatory requirements for wetland impact assessment and compensatory mitigation.
The data base for the form factors of the nucleon obtained from elastic ep scattering is discussed, as well as some recent developments in their calculation.
Degradation of cellulosics or starch in alkaline solution produces mostly organic acids which are monocarboxylic in nature. Seven of the organic acids have been identified as formic, acetic, glycolic, lactic, 2-hydroxybutyric, 2-hydroxyisobutyric and 2-hydroxyvaleric acids. In total, their yields amount to 41-46% of starting material weight.
With collaboration between chemistry, X-ray crystallography, and molecular modeling, we designed and synthesized a series of novel piperazine sulfonamide BACE1 inhibitors. Iterative exploration of the non-prime side and S2prime sub-pocket of the enzyme culminated in identification of an analog that potently lowers peripheral Ab40 in transgenic mice with a single subcutaneous dose.
Thlaspi caerulescens is a heavy metal hyperaccumulator plant species that is able to accumulate extremely high levels of zinc (Zn) and cadmium (Cd) in its shoots (30,000 μg...Full Text Available
Populations living close to high-voltage transmission lines often have residential magnetic field exposures in excess of 1 microT, and sometimes over 2 microT. Yet, populations studied in most epidemiologic...Full Text Available
An energy frontier or QCD Explorer ep and collider can be realized by colliding high-energy photons generated by Compton backscattered off a CLIC electron beam, at either 75 GeV or 1.5 TeV, with protons or ions stored in the LHC. In this study we discuss a performance optimization of this type of collider by tailoring the parameters of both CLIC and LHC. An estimate of the ultimately achievable luminosity is given.
Mycoreovirus 1 (MyRV1), a member of the Reoviridae family possessing a genome consisting of 11 dsRNA segments (S1–S11), and the prototype hypovirus (CHV1-EP713)...Full Text Available
Growth differentiation factor-9 (GDF-9), an oocyte-secreted member of the transforming growth factor β superfamily, progesterone receptor, cyclooxygenase 2 (Cox2; Ptgs2), and the EP2 prostaglandin...Full Text Available
Microstructure characterization is important for controlling the quality of laser welding. In the present work, a detailed microstructure characterization by transmission electron microscopy was carried out on the laser welding cast Ni-based superalloy K418 turbo disk and alloy steel 42CrMo shaft and an unambiguous identification of phases in the weldment was accomplished. It was found that there are {gamma}-FeCrNiC austenite solid solution dendrites as the matrix, (Nb, Ti) C type MC carbides, fine and dispersed Ni{sub 3} Al {gamma}' phase as well as Laves particles in the interdendritic region of the seam zone. A brief discussion was given for their existence based on both kinetic and thermodynamic principles.
Microstructure characterization is important for controlling the quality of laser welding. In the present work, a detailed microstructure characterization by transmission electron microscopy was carried out on the laser welding cast Ni-based superalloy K418 turbo disk and alloy steel 42CrMo shaft and an unambiguous identification of phases in the weldment was accomplished. It was found that there are #gamma#-FeCrNiC austenite solid solution dendrites as the matrix, (Nb, Ti) C type MC carbides, fine and dispersed Ni_3 Al #gamma#' phase as well as Laves particles in the interdendritic region of the seam zone. A brief discussion was given for their existence based on both kinetic and thermodynamic principles.
For many centuries paper was the main material for recording cultural achievements all over the world. Paper is mostly made from cellulose with small amounts of organic and inorganic additives, which allow its identification and characterization and may also contribute to its degradation. Prior to 1850, paper was made entirely from rags, using hemp, flax and cotton fibres. After this period, due to the enormous increase in demand, wood pulp began to be commonly used as raw material, resulting in rapid degradation of paper. Spectroscopic techniques represent one of the most powerful tools to investigate the constituents of paper documents in order to establish its identification and its state of degradation. This review describes the application of selected spectroscopic techniques used for paper characterization and conservation. The spectroscopic techniques that have been used and will be reviewed ...
Background: Differentiation between reactive, but morphologically atypical, mesothelial cells and adenocarcinoma in effusions can be problematic. Elaborate immunohistochemical...Full Text Available
The present status of theoretical description of deep-inelastic lepton-nucleon as well as large angle Bhabha scattering with account for radiative corrections in the leading and next-to-leading approximations are reviewed. Also considered is a build-up principle and physical programme of the photon-photon colliders
Radiation-and-thermal-combined degradation of ethylene-propylene rubber (EP rubber) and chlorosulfonated polyethylene (CSM) as cable insulating and jacketing materials were evaluated by accelerated aging tests and a method to assess the lifetime of these materials under practical application was studied. EP rubber and CSM of experimental formulation were degraded at accelerated rates, that are 50 [approx] 1000 times the degradation rate under a standard condition (1Gy/h, 50degC). The degradation was investigated by measuring the tensile properties. In the accelerated aging tests, rates of elongation decrease owing to degradation for both EP rubber and CSM were in proportion to increase in accelerated rate. Behaviors of elongation changes showed little difference with accelerated rate. EP rubber lifetime estimated from sequential aging test had a tendency to extend beyond that from simultaneous aging ...
Radiation-and-thermal-combined degradation of ethylene-propylene rubber (EP rubber) and chlorosulfonated polyethylene (CSM) as cable insulating and jacketing materials were evaluated by accelerated aging tests and a method to assess the lifetime of these materials under practical application was studied. EP rubber and CSM of experimental formulation were degraded at accelerated rates, that are 50 #approx# 1000 times the degradation rate under a standard condition (1Gy/h, 50degC). The degradation was investigated by measuring the tensile properties. In the accelerated aging tests, rates of elongation decrease owing to degradation for both EP rubber and CSM were in proportion to increase in accelerated rate. Behaviors of elongation changes showed little difference with accelerated rate. EP rubber lifetime estimated from sequential aging test had a tendency to extend beyond that from simultaneous aging ...
The adsorption of mercury vapor on particles was studied by using soot particles generated by incineration of sewage sludge (EP-ash) and activated carbon particles. Through the experiments, it was found that, at 298 K, the EP-ash has a fairly high adsorption capacity for mercury vapor in the order of 10/sup -6/g/g, which is between that of the ordinary soils and that of activated carbon particles. Furthermore, it was found that physical adsorption of mercury vapor on the studied particles at high temperature is described by Dubinin's equation. On the basis of the equation, it was shown that EP-ash physically adsorbs very little mercury at high temperature, and therefore, most mercury in the EP-ash is chemically adsorbed or contained in a form of mercury compounds. Nevertheless, the total amount of mercury contained in the particles is very little compared to the total mercury in the exhaust ...
Simple recursion formulas are derived for the multiplicities of the dominant weight vectors appearing in a class of irreducible highest weight representations of the indecomposable affine Kac-Moody algebras. This class is characterized by the appearance of exactly two distinct infinite sequences of dominant weight vectors. The general procedure used for the enumeration of these representations and for the derivation of the corresponding multiplicity formulas is that presented by Capps for the analysis of those irreducible representations containing exactly one such infinite sequence. This procedure includes the classification of representations in terms of congruence and the identification of Weyl orbits by the norm of the dominant weight. Some of the results presented have application to physical theories such as string field theories.
The atlas presents sequences of MRI sections parallel to the orbito-meatal plane in children from birth through the age of sixteen years. Each child was studied horizontally and sagitally and three-dimensional brain images were reconstructed to facilitate accurate identification of sulci and gyri. The images show crucial aspects of brain development such as the constancy of the brain stem and primitive brain from birth onward; the development of the telencephalon, characterized by deepening of sulci and growth of the cerebral cortex surface; and the different stages of white matter myelinization.
Steam generator tube denting is primarily caused by build-up of corrosion products at the tubesheet and the tube support plates. The mechanism of dent growth and the identification of tubes which should be removed from service have been studied. The practical outcome has been to prevent in-service tube leaks and to avoid unnecessary plugging of large numbers of tubes. A finite element study of tubesheet deformation (of pulled leaking tubes from reactors) was undertaken. Profilometry results for characterizing dents are given. Although several modifications have been made the high resolution profilometry system performance and the results obtained have proved satisfactory. (U.K.).
Nano-indentation has been used to assess the hardness of equiaxed grains of #alpha#-Ti as a function of orientation. Surface normals of these grains in metallographic sections were assessed using orientation imaging microscopy. Thin membranes of material from below a series of nano-indentations were excised by use of a dual-beam focused ion beam instrument. In this way, the dislocation substructures beneath individual indentations were characterized using transmission electron microscopy, permitting an identification of both statistically stored and geometrically necessary dislocations.
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in-place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional and multi-component seismic area is being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with extended-reach jetting lance and other ultra-short radius lateral technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil-in-place will result in additional oil production by primary and enhanced recovery processes.
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in-place, methods for improved completion efficiency and the suitability of waterflooding in Red River and Ratcliffe shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing three-dimensional and multi-component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with extended-reach jetting lance and other ultra-short-radius lateral technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil in place will result in additional oil recovery by primary and enhanced recovery ...
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in-place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional (3D) and multi-component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with short-lateral and horizontal drilling technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil-in-place will result in additional oil production by primary and enhanced recovery processes.
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in-place, methods for improved completion efficiency and the suitability of waterflooding in Red River and Ratcliffe shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing three-dimensional and multi-component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with extended-reach jetting lance and other ultra-short-radius lateral technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil in place will result in additional oil recovery by primary and enhanced recovery ...
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in- place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional (3D) and multi- component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with short- lateral and horizontal drilling technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil-in-place will result in additional oil production by primary and enhanced recovery processes.
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determination of oil-in-place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional (3D) is being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with short lateral and horizontal drilling technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil-in- place will result in additional oil production by primary and enhanced recovery processes.
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in- place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional (3-D) and multi-component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with short-lateral and horizontal drilling technologies. Improved completion efficiency, additional wells at closer spacing and better estimate of oil-in-place will result in additional oil production by primary and enhanced recovery processes.
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in- place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional (3-D) and multi- component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with short- lateral and horizontal drilling technologies. Improved completion efficiency, additional wells at closer spacing and better estimate of oil-in-place will result in additional oil production by primary and enhanced recovery processes.
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in-place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing three-dimensional is being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with short-lateral and horizontal drilling technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil-in-place will result in additional oil production by primary and enhanced recovery processes.
Background In chordates, retinoid metabolism is an important target of short-chain dehydrogenases/reductases (SDRs). It is not known whether SDRs play a role in retinoid metabolism of protostomes, such as Drosophila melanogaster. Methods Drosophila genome was searched for genes encoding proteins with ?50% identity to human retinol dehydrogenase 12 (RDH12). The corresponding proteins were expressed in Sf9 cells and biochemically characterized. Their phylogenetic relationships were analyzed using PHYLIP software. Results A total of six Drosophila SDR genes were identified. Five of these genes are clustered on chromosome 2 and one is located on chromosome X. The deduced proteins are 300 to 406 amino acids long and are associated with microsomal membranes. They recognize all-trans-retinaldehyd...
A comparative test in mice for pulmonary toxicity between butylated hydroxytoluene (2,6-di-tert.-butyl-4-methylphenol, BHT) and 2,6-di-tert.-butyl-4-(alpha, alpha, alpha-2H3)methylphenol (BHT-d3) showed a significantly lower toxic potency of the latter. The rate of in vitro BHT metabolism to 2,6-di-tert.-butyl-4-methylene-2,5-cyclohexadienone (BHT-QM) was slowed by deuterating BHT in the 4-methyl group. On the other hand, the rate of in vitro metabolism to 2,6-di-tert.-butyl-4-hydroxy-4-methyl-2,5-cyclohexadienone (BHT-OH) was increased with the deuteration. A similar isotope effect of the deuterium substitution on the in vivo metabolic rates of BHT was observed. These observations support the concept that the lung damage caused by BHT is mediated by BHT-QM. The pulmonary toxicity of 2-tert.-butyl-4-ethylphenol (4-EP) and their deuterated analogs was also compared. 2-tert.-Butyl-4-(1,1-2H2)ethylphenol (4-EP-d2) showed a significantly lower ...
This report describes the method of Allan variance and its application to the characterization of a Ring Laser Gyro`s (RLG) performance. Allan variance, a time domain analysis technique, is an accepted IEEE standard for gyro specifications. The method was initially developed by David Allan of the National Bureau of Standards to quantify the error statistics of a Cesium beam frequency standard employed as the US Frequency Standards in 1960`s. The method can, in general, be applied to analyze the error characteristics of any precision measurement instrument. The key attribute of the method is that it allows for a finer, easier characterization and identification of error sources and their contribution to the overall noise statistics. This report presents an overview of the method, explains the relationship between Allan variance and power spectral density distribution of underlying noise sources, describes the batch and ...
Recent technological developments have facilitated intensified searches for genetic markers under selection in nonmodel species. Here, we present an approach for the identification of candidate gene variation in nonmodel organisms. We report on the characterization of 82 single nucleotide polymorphisms (SNPs) and on the development of a specific genotyping assay for 30 SNPs in 18 candidate genes for growth and reproduction in Atlantic cod (Gadus morhua). These markers can be used for scanning natural populations for signatures of selection in both contemporary and archived historical samples, for example in retrospective studies assessing the effects of environmental changes, such as increasing temperatures, and selection imposed by high fishing pressure. Furthermore, these gene markers may be of interest to aquaculture, serving as a starting point for linking phenotypic traits important for productivity with genotypes and potentially be of use ...
The objectives of this study were to characterize the changes of VOC material emission profiles over time and develop a method to account for such changes in order to enhance a source identification technique that is based on the measurements of mixed air samples and the emission signatures of individual building materials determined by PTRMS. Source models, including powerlaw model, doubleexponential decay model and mechanistic diffusion model, were employed to track the change of individual material emission signatures by PTRMS over a ninemonth period. Samples of nine typical building materials were tested individually for nine months and later in combination to obtain actual mixture emissions. VOC emissions from each material were measured in a 50liter smallscale chamber. Chamber air was sampled by PTRMS over a 28day period to determine their emission rate decay characteristics as well as to establish the initial profile of emission ...
Radiation-and-thermal-combined degradation of some kinds of cable insulating and jacketing materials was evaluated by accelerated aging tests. Plasticized polyvinyl chloride (PVC), silicone rubber, crosslinked and non-crosslinked halogen-free flame-retardant polyolefins (NH-XLPO and NH-PO) and ethylene-propylene rubber (EP rubber) of experimental formulation were degraded at accelerated rates, that are 50-1000 times the degradation rate under standard conditions (e.g.; 1Gy/h, 50degC), and a method to assess the lifetime of these materials under standard conditions was studied. The degradation was investigated by measuring tensile properties. In the accelerated aging tests, rates of elongation decrease owing to degradation for these materials were in proportion to the increase in accelerated rate. The PVC lifetime estimated from sequential aging tests had a tendency to extend beyond that from simultaneous aging tests, while the lifetime of other materials estimated ...
Sparse learning has recently received increasing attention in many areas including machine learning, statistics, and applied mathematics. The mixed-norm regularization based on the L1/Lq norm with q > 1 is attractive in many applications of regression and classification in that it facilitates group sparsity in the model. The resulting optimization problem is, however, challenging to solve due to the structure of the L1/Lq -regularization. Existing work deals with special cases including q = 2,infinity, and they cannot be easily extended to the general case. In this paper, we propose an efficient algorithm based on the accelerated gradient method for solving the L1/Lq -regularized problem, which is applicable for all values of q larger than 1, thus significantly extending existing work. One key building block of the proposed algorithm is the L1/Lq -regularized Euclidean projection (EP1q). Our theoretical analysis reveals the key properties of ...
Kerf geometry, kerf wall features, and cutting front characteristics of an Abrasive Waterjet (AWJ) machined Graphite/Epoxy (Gr/Ep) laminate were studied. A macroscopic analyses suggests that geometrical features associated with AWJ machining of Gr/Ep laminates are influenced by three macro regions along the cutting depth. The presence of these regions, including initial damage at jet entry, smooth cutting, and rough cutting near the jet exit, depends on the operating conditions. Design of experiments and analysis of variance were used to determine the effect of cutting parameters on kerf characteristics and to develop empirical models for kerf profile and features of the three distinct macroscopic regions. Cutting front analysis revealed that the mechanisms of material removal in AWJ machining of Gr/Ep do not change over the jet penetration depth. In general, high quality uniform cuts may be obtained by minimizing initial ...
November 1989, marked the beginning of a new three-year cycle of DOE grant support, in connection with which the program underwent a major reorganization. This document presents the progress on the three objectives of the present program which are: to isolate by the technique of two-dimensional polyacrylamide gel electrophoresis (2-D PAGE), proteins of special interest because of the relative mutability of the corresponding gene, establish the identity of the protein, and, for selected proteins, move to a characterization of the corresponding gene; to develop a more efficient approach, based on 2-D PAGE, for the detection of variants in DNA, with special reference to the identification of mutations in the parents of the individual whose DNA is being examined; and, to continue an effective interface with the genetic studies on the children of atomic bomb survivors in Japan, with reference to both the planning and implementation of new studies at ...
Analytical methods developed to sample and characterize ambient organic aerosols often face the trade-off between long sampling times and the loss of detailed information regarding specific chemical species present. In the work presented here, high-time resolution ambient measurements (3.5 minutes) are achieved by using the Photoionization Aerosol Mass Spectrometer (PIAMS) in conjunction with the mini-Versatile Aerosol Concentration Enrichment System (m-VACES). Aerosol sampling took place for one week at State of Delaware Air Quality Monitoring Site in Wilmington, Delaware in June 2006. The soft, universal ionization scheme of PIAMS allows for identification of various chemical compounds by a signature ion, often the molecular ion. Meteorological data was used to link some species, such as...
Carotenoids are highly beneficial for human nutrition and health because they provide essential nutrients and important antioxidants in our diets. However, many food crops, especially the major staple crops contain only trace to low amounts of carotenoids. Although significant progress has been made in developing food crops rich in carotenoids by altering the expression of carotenoid biosynthetic genes, in many cases it has proved to be difficult to reach the desired levels of carotenoid enrichment. The recent identification and characterization of a novel gene mutation in cauliflower reveals that creating a metabolic sink to sequester carotenoids is an important mechanism to control carotenoid accumulation in plants. The successful demonstration of increased carotenoid accumulation in ass...
Laser welding of AISI 904 L super austenitic stainless steel using a diffusion cooled slab 3.5kW CO2 laser and employing two different shielding gases, namely argon and helium, was carried out. The laser weld bead profile depends on various parameters such as beam power (BP), travel speed (TS) and focal position (FP) of the laser spot. These parameters have to be selected suitably to obtain the desirable output. The cross sectioned area of the bead profiles measured using an optical microscope to determine the bead width and depth of penetration. X-ray diffraction used for phase identification confirmed that the weld structure was fully austenitic and dendritic. Hardness was observed to increase in the weld bead with respect to the parent metal and it was related to the microstructural ref...
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in- place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional (3D) and multi-component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. Field demonstrations are in progress to collect data for evaluation of horizontal completions in both the Red River and Ratcliffe. A vertical well in the Red River will test attribute analysis of 3D seismic data for prediction of porosity development. Additional seismic acquisitions and interpretation are in progress for both the Ratcliffe and Red River. A water-injectivity test in a new horizontal completion in the Red Rive B zone ...
Keratinocyte growth factor receptor (KGFR) and fibroblast growth factor receptor (FGFR) 2c share identical amino acid sequences, except for a 46-amino acid domain in the extracellular region. Monoclonal antibodies (MAbs) specific to KGFR have not been reported nor are commercially available. In this study, we generated murine MAbs specific to KGFR in non-obese diabetic (NOD) mice using a modified Repeated Immunizations at Multiple Sites (RIMMS) technology. Stable cell lines expressing the full-length human KGFR or FGFR2c were produced to facilitate the identification of KGFR-specific MAbs. Following the initial screening of hybridoma clones with a fluorescence-based, confocal cell detection method and ELISA, KGFR-specific MAbs were selected and confirmed by flow cytometry and Western blot ...
A crack fault is one of the damage modes most frequently occurring in gears. Identifying different crack levels, especially for early cracks is a challenge in gear fault diagnosis. This paper aims to propose a method to classify the different levels of gear cracks automatically and reliably. In this method, feature parameters in time domain, specially designed for gear damage detection and in frequency domain are extracted to characterize the gear conditions. A two-stage feature selection and weighting technique (TFSWT) via Euclidean distance evaluation technique (EDET) is presented and adopted to select sensitive features and remove fault-unrelated features. A weighted K nearest neighbor (WKNN) classification algorithm is utilized to identify the gear crack levels. The gear crack experime...
This is a report of extraction and identification of 1-O-alkyl glycerol present in the dried leaves of Bauhinia scandens. Fifty percent aqueous ethanolic extract of the plant at room temperature was fractionated over petroleum ether and diethyl ether. The diethyl ether soluble fraction showed positive bioactivity in Brine Shrimp bioassay. Isolation and purification of the active principle was subsequently done from diethyl ether fraction. The diethyl ether fraction was separated into acidic and neutral part. The acid free fraction was screened to be positive in Brine Shrimp bioassay. The NMR spectra (in CDCl3) indicated the probability of its lipoidal nature. The total lipid fraction was resolved into neutral, glyco, and phospho-lipids by column chromatography. Only the neutral fraction sh...
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in- place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional and multi-component seismic area is being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with extended- reach jetting lance and other ultra-short radius lateral technologies. Improved completion efficiency, additional wells at closer spacings better estimates of oil-in-place will result in additional oil production by primary and enhanced recovery processes. ...
Our work is towards mechanistically understanding interactions of unsaturated bacterial biofilms and their extracellular polymeric substances (EPS) with actinide metals and metal surrogates under vadose zone conditions. Because metal contaminants in the vadose zone co-occur with organic pollutants, some of our work has included experiments with organic pollutants.
We discuss the search of excited leptons and quarks with spin 1/2 at #gamma##gamma# and at #gamma#e colliders. We show that #gamma##gamma# colliders have important advantages for the observation of excited leptons and quarks in comparison with ee, ep, and pp colliders discussed in previous papers. These collisions give a simple test for the chirality of the l"*l#gamma# transition. The anomalous magnetic moment of excited leptons can be observed when its value is not too small. (orig.).
Full text: Verification of the dose delivered to a patient during radiotherapy is an important quality assurance procedure, however this is rarely performed due to the extra time involved. Electronic portal images (EPIs) are currently acquired at many centres during radiotherapy treatment for positioning verification. These could be utilised for dose verification provided 1) an accurate prediction of the dose transmitted through the patient to the EPID can be produced for the patients' radiotherapy beams, and, 2) the EPID image can be converted to an accurate measured dose. Ideally, the radiotherapy planning system (RTPS) would be used to produce the predicted dose as part of the planning procedure. The aim of this project is to investigate whether the convolution-superposition model of the Pinnacle RTPS can accurately calculate dose transmitted through a patient and deposited in a phantom at a large source to surface distance. The dose transmitted through a uniform (patient) phantom ...
This topical report is a compilation of characterizations by different disciplines of the Red River Formation in the southwest portion of the Williston Basin and the oil reservoirs which it contains in an area which straddles the state line between North Dakota and South Dakota. Goals of the report are to increase understanding of the reservoir rocks, oil-in-place, heterogeneity, and methods for improved recovery. The report is divided by discipline into five major sections: (1) geology, (2) petrography-petrophysical, (3) engineering, (4) case studies and (5) geophysical. Interwoven in these sections are results from demonstration wells which were drilled or selected for special testing to evaluate important concepts for field development and enhanced recovery. The Red River study area has been successfully explored with two-dimensional (2D) seismic. Improved reservoir characterization utilizing 3-dimensional (3D) and has been investigated for ...
The possibility of gamma-absorption identification of the analyzed substance is considered. the basic provisions of the proposed method are concentrated on the example of carbohydrates and hydrocarbons. The above method is tested experimentally on polyethylenes and polystyrene
In recent years, Clostridium species have rapidly reemerged as human and animal pathogens. The detection and identification of pathogenic Clostridium species...Full Text Available
As adulterated and substituted Chinese medicinal materials are common in the market, therapeutic effectiveness of such materials cannot be guaranteed. Identification at species-, strain- and locality-levels,...Full Text Available
This thesis describes the analysis of the semileptonic decay D{sup 0} {yields} {bar K}{sup 0} {pi}{sup -} {mu}{sup +}{nu} using FOCUS data. FOCUS is a fixed target experiment at Fermilab that studies the physics of the charm quark. Particles containing charm are produced by photon-gluon fusion from the collision of a photon beam on a BeO target. The experiment is characterized by excellent vertex resolution and particle identification. The spectrometer consists of three systems for track reconstruction (two silicon systems and one multiwire proportional chamber system) and two magnets of opposite polarity. The polarity of the magnet is such that the events of e{sup +}e{sup -} pairs produced in the target (which constitutes the main background) travel through a central opening in the detectors without interactions. Particle momentum is measured from the deflection angle in the magnets. Three multicell Cerenkov counters are used for charged ...
The purpose of this project was to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in-place, and methods for improved completion efficiency. The investigations and demonstrations were focussed on Red River and Ratcliffe reservoirs in the Williston Basin within portions of Montana, North Dakota and South Dakota. Both of these formations have been successfully explored with conventional 2-dimensional (2D) seismic. Improved reservoir characterization utilizing 3-dimensional (3D) seismic was investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterizations were integrated with geological and engineering studies. The project tested lateral completion techniques, including high-pressure jetting lance technology and short-radius lateral drilling to enhance completion efficiency. Lateral completions should improve economics for both ...
The research for the development of flexible organic electronic devices (FEDs) is rapidly increasing worldwide, since FEDs will change radically several aspects of everyday life. Although there has been considerable progress in the area of flexible inorganic devices (a-Si or solution processed Si), there are numerous advances in the organic (semiconducting, conducting and insulating), inorganic and hybrid (organic-inorganic) materials that exhibit customized properties and stability, and in the synthesis and preparation methods, which are characterized by a significant amount of multidisciplinary efforts. Furthermore, the development and encapsulation of organic electronic devices onto flexible polymeric substrates by large-scale and low-cost roll-to-roll production processes will allow their market implementation in numerous application areas, including displays, lighting, photovoltaics, radio-frequency identification circuitry and chemical ...
Due to the large number of chemicals in commerce without adequate toxicity characterization data, coupled with an ineffective federal policy for chemical management in the United States, many states are grappling with the challenge to identify toxic chemicals that may pose a risk to human health and the environment. Specific populations (e.g., children, elderly) are particularly sensitive to these toxic chemicals. In 2008, the Children's Safe Product Act (CSPA) was passed in Washington State. The CSPA included specific requirements to identify High Priority Chemicals (HPCs) and Chemicals of High Concern to Children (CHCCs). To implement this legislation, a methodology was developed to identify HPCs from authoritative scientific and regulatory sources on the basis of toxicity criteria. Another set of chemicals of concern was then identified from authoritative sources, based on their potential exposure to children. Exposure potential was evaluated by identifying ...
The pharmacology of the alpha-2 adrenoceptor of the human adipocyte was improved by using some new alpha-2 antagonists from different chemical families (imidazolines, benzazepines and benzofuroquinolizines) in biological and binding assays. Moreover, investigations were also carried out to define the binding properties of a new imidazolinic antagonist, RX821002 (2-(2-methoxy-1,4-benzodioxan-2yl)-2-imidazoline), which could be a potential radioligand. (3H)RX821002 binding was very rapid and reversible. Saturation isotherms indicated that (3H)RX821002 labeled, with high affinity, a homogeneous population of noninteracting binding sites with a mean Kd of 0.98 +/- 0.05 nM (n = 6). The binding of (3H)RX821002 on the human fat cell alpha-2 adrenoceptor displayed a specificity which is strictly similar to that obtained with (3H)rauwolscine and which is classical for an alpha-2 A adrenoceptor. The binding parameters of (3H)RX821002 were compared with those obtained with the classical alpha-2 ...
This report documents the Mixed Waste Focus Area (MWFA)-sponsored Alternative Technology Workshop held in Salt Lake City, Utah, from January 24--27, 1995. The primary workshop goal was identifying potential applications for emerging technologies within the Options Analysis Team (OAT) ''wise'' configuration. Consistent with the scope of the OAT analysis, the review was limited to the Mixed Low-Level Waste (MLLW) fraction of DOE's mixed waste inventory. The Los Alamos team prepared workshop materials (databases and compilations) to be used as bases for participant review and recommendations. These materials derived from the Mixed Waste Inventory Report (MWIR) data base (May 1994), the Draft Site Treatment Plan (DSTP) data base, and the OAT treatment facility configuration of December 7, 1994. In reviewing workshop results, the reader should note several caveats regarding data limitations. Link-up of the MWIR and DSTP data bases, while representing the most comprehensive array of mixed ...
Abstract Bartonella are arthropod-borne, fastidious, Gram-negative, and aerobic bacilli distributed by fleas, lice, sand flies, and, possibly, ticks. The zoonotic Bartonella species, Bartonella henselae and Bartonella clarridgeiae, which are the causes of cat scratch disease and endocarditis in humans, have been reported from cats, cat fleas, and humans in Australia. However, to date, there has been no report of B. henselae or B. clarridgeiae in Australian wild animals and their ectoparasites. B. henselae and B. clarridgeiae were detected in fleas (Ctenocephalides felis) from red foxes (Vulpes vulpes), an introduced pest animal species in Australia, and only B. clarridgeiae was detected in blood from one red fox. Phylogenetic analysis of the ribosomal intergenic spacer region revealed that the B. henselae detected in the current study were related to B. henselae strain Houston-1, a major pathogenic strain in humans in Australia, and confirmed the genetic distinctness of B. ...
An updated listing of the vascular plants of the Hanford Site is provided, along with discussions of how humans may interact with local plants and have influenced the regional flora. Based on examinations of herbarium collections at the Westinghouse Hanford Company, Pacific Northwest Laboratory, Washington State University, and Brigham Young University, 590 vascular plant species have been identified on or near the Hanford Site. This is more than twice the number of species on previously published lists of Hanford Site vascular plants. A review of the plant species that are currently listed as endangered, threatened, sensitive, or otherwise of concern to the Washington State Natural Heritage Program and the Federal Fish and Wildlife Service is included. Color photographs of selected species are included to aid identification. Lists are provided of the Hanford Site plant species that could be used as food and medicinal sources and of those introduced to the region ...
Complex abdominal lesions include a variety of pathologies, such as septated, infected, and hemorrhagic cysts, abscesses, tumors, and fluid collections of different ethiology. These lesions present diagnostic difficulties with both Ultrasonography (US) and Computed Tomography (CT), since findings may not be present or, when present, are not specific. Keeping these limitations in mind, we evaluated 105 patients (111 abdominal lesions) with both US and CT in order to compare their adequacy in predicting the nature of the lesion. On the basis of US and CT results, complex abdominal lesions were divided in four classes: class I includes 43 cases in which both examinations gave the same contribution to the definition of the nature of the lesion, class II (14 lesions, mainly sperimentated cysts), in which US was superior to CT, class III includes 45 cases of hemorrhagic cysts, abscesses, fluid collections and, less frequently, cystic tumors; class IV includes 9 cases in which US and CT ...
Due to the fact that, the workers' behavior is characterized by its complexity and diversity, this issue has been seen as a great 'black box' in discussions regarding the Management Systems of SHE. Associated with this issue other arises: How conscious people? How to engage them with the process? How to improve the risk control? How to motivate the prevention? Most of these responses are discussed in the Social and Human Sciences for many years. However, it is necessary to closer the technical-operational knowledge and the human aspects, applying in the organizations' daily work, to make the working environment more safe. The purpose of this study, therefore, is examining the possibility of reducing accidents through the identification and treatment of deviations (unsafe acts and unsafe conditions), cause the whole accident, be it serious or not, begins with a small deviation. It was used as a reference tool, ...
Detailed investigations of geologic, geomorphic, and seismic conditions at the Bodo Canyon disposal site were conducted. The purpose of these investigations was basic site characterization and identification of potential geologic hazards that could affect long-term site stability. Subsequent engineering studies, such as analyses of hydrologic and liquefaction hazards, used the data developed in these studies. The geomorphic analysis was employed in the design of effective erosion protection. Studies of the regional and local seismotectonic setting, which included a detailed search for possible capable faults within a 65 kilometer radius of the site, provided the basis for seismic design parameters. The scope of work performed included the following: Compilation and analysis of previous published and unpublished geologic literature and maps; Review of historical and instrumental earthquake data; Review of site-specific subsurface geologic data, ...
The {sup 252}Cf-source-driven noise analysis method is a versatile measurements tool that has been applied to measurements for initial loading of reactors, quality assurance of reactor fuel elements, fuel processing facilities, fuel reprocessing facilities, fuel storage facilities, zero-power testing of reactors, verification of calculational methods, process monitoring, characterization of storage vaults, and nuclear weapons identification. This method`s broad range of application is due to the wide variety of time- and frequency domain signatures, each with unique properties, obtained from the measurement. The following parameters are obtained from this measurement: average detector count rates, detector multiplicities, detector autocorrelations, cross-correlation between detectors, detector autopower spectral densities, cross-power spectral densities between detectors, coherences, and ratios of spectral densities. All of these measured ...
Four proteins from NCBI cog1816, previously annotated as adenosine deaminases, have been subjected to structural and functional characterization. Pa0148 (Pseudomonas aeruginosa PAO1), AAur1117 (Arthrobacter aurescens TC1), Sgx9403e, and Sgx9403g have been purified and their substrate profiles determined. Adenosine is not a substrate for any of these enzymes. All of these proteins will deaminate adenine to produce hypoxanthine with k(cat)/K(m) values that exceed 10(5) M(-1) s(-1). These enzymes will also accept 6-chloropurine, 6-methoxypurine, N-6-methyladenine, and 2,6-diaminopurine as alternate substrates. X-ray structures of Pa0148 and AAur1117 have been determined and reveal nearly identical distorted (?/?)(8) barrels with a single zinc ion that is characteristic of members of the amidohydrolase superfamily. Structures of Pa0148 with adenine, 6-chloropurine, and hypoxanthine were also determined, thereby permitting identification of the ...
The objectives of the project were (i) to develop a combination iron oxide production and carbon sequestration plant that will use serpentine ores as the source of iron and the extraction tailings as the storage element for CO2 disposal, (ii) the identification of locations within the US where this process may be implemented and (iii) to create a standardized process to characterize the serpentine deposits in terms of carbon disposal capacity and iron and steel production capacity. The first objective was not accomplished. The research failed to identify a technique to accelerate direct aqueous mineral carbonation, the limiting step in the integration of steel production and carbon sequestration. Objective (ii) was accomplished. It was found that the sequestration potential of the ultramafic resource surfaces in the US and Puerto Rico is approximately 4,647 Gt of CO2 or over 500 years of current US production of CO2. Lastly, a computer model ...
The chicken extracellular matrix glycoprotein ES/130 is necessary for epithelial-mesenchymal transformation in the developing hear and is also expressed in noncardiac chicken tissues such as limb and notochord. We have identified hES, the human homology of chicken ES/130. Fluorescence in situ hybridization analysis (FISH) localizes hES to human chromosome 20p11.2-p12. FISH analyses of individuals with 20p12 deletions and affected by Alagille syndrome exclude hES as a candidate gene for this disorder. Reverse transcriptase-polymerase chain reaction studies reveal that hES is expressed in both fetal and adult human tissues and that hES expression in the left ventricle is increased in the failing adult heart. Further studies will evaluate how hES mutations may relate to congenital human cardiac and skeletal anomalies as well as cardiac remodeling in the adult. 16 refs., 2 figs.
A crack fault is one of the damage modes most frequently occurring in gears. Identifying different crack levels, especially for early cracks is a challenge in gear fault diagnosis. This paper aims to propose a method to classify the different levels of gear cracks automatically and reliably. In this method, feature parameters in time domain, specially designed for gear damage detection and in frequency domain are extracted to characterize the gear conditions. A two-stage feature selection and weighting technique (TFSWT) via Euclidean distance evaluation technique (EDET) is presented and adopted to select sensitive features and remove fault-unrelated features. A weighted K nearest neighbor (WKNN) classification algorithm is utilized to identify the gear crack levels. The gear crack experiments were conducted and the vibration signals were captured from the gears under different loads and motor speeds. The proposed method is applied to identifying the gear crack ...
Both the increased complexity of integrated circuits, resulting in six or more levels of integration, and the increasing use of flip-chip packaging have driven the development of integrated circuit (IC) failure analysis tools that can be applied to the backside of the chip. Among these new approaches are focused ion beam (FIB) tools and processes for performing chip edits/repairs from the die backside. This paper describes the use of backside FIB for a failure analysis application rather than for chip repair. Specifically, they used FIB technology to prepare an IC for inspection of voided metal interconnects (lines) and vias. Conventional FIB milling was combined with a super-enhanced gas assisted milling process that uses XeF{sub 2} for rapid removal of large volumes of bulk silicon. This combined approach allowed removal of the TiW underlayer from a large number of Ml lines simultaneously, enabling rapid localization and plan view imaging of voids in lines and vias with backscattered ...
This study effort was required as a preliminary step prior to initiation of field measurements of atmospheric dispersion in coastal regions. The Nuclear Regulatory Commission (NRC) is in the process of planning an extensive field measurement program to generate data which will serve as improved data bases for licensing decisions, confirmation of regulations, standards, and guides, and for site characterizations. The study being reported here is an effort directed to obtaining as much information as is possible from existing studies that is relevant toward NRC's objectives. For this study, reports covering research and meteorological measurements conducted for industrial purposes, utility needs, military objectives, and academic studies were obtained and critically reviewed in light of NRC's current data needs. This report provides an interpretation of the extent of existing usable information, an indication of the potential for tailoring existing ...
In supervising CANDU plant operation, Operations staff must routinely monitor plant status using information from several information systems. One key source of plant status information are the CRT displays at console workstations and panel locations. At Darlington, as at most CANDU plants, Operations staff have adopted a reference set of displays for use in monitoring during Full Power Steady State conditions. The display set employed was chosen from the available suite of displays, and operational experience has demonstrated that the current displays could be improved. For Outages, no reference display set has been defined, and for Upset conditions, the current Transient display set does not provide the information needed by operations staff, and consequently is not used. This paper describes the basis for and findings from a COG project [1] undertaken in 1997 to characterize monitoring practice and develop improvements to control room displays to better support ...
Autism is a pervasive developmental condition, characterized by impairments in non-verbal communication, social relationships and stereotypical patterns of behavior. A large body of evidence suggests that several aspects of face processing are impaired in autism, including anomalies in gaze processing, memory for facial identity and recognition of facial expressions of emotion. In search of neural markers of anomalous face processing in autism, much interest has focused on a network of brain regions that are implicated in social cognition and face processing. In this review, we will focus on three such regions, namely the STS for its role in processing gaze and facial movements, the FFA in face detection and identification and the amygdala in processing facial expressions of emotion. Much evidence suggests that a better understanding of the normal development of these specialized regions is essential for discovering the neural bases of face ...
The effects of atrial natriuretic peptide (ANP), oxytocin (OT) and vasopressin (AVP) on guanylate cyclase activity and cyclic GMP accumulation were examined, since these hormones appear to be intimately associated with blood pressure and intravascular volume homeostasis. ANP was found to increase cyclic GMP accumulation in ten cell culture systems, which were derived from blood vessels, adrenal cortex, kidney, lung, testes and mammary gland. ANP receptors were characterized in intact cultured cells using {sup 125}I-ANP{sub 8-33}. Specific {sup 125}I-ANP binding was saturable and of high affinity. Scratchard analysis of the binding data for all cell types exhibited a straight line, indicating that these cells possessed a single class of binding sites. Despite the presence of linear Scatchard plots, these studies demonstrated that cultured cells possess two functionally and physically distinct ANP-binding sites. Most of the ANP-binding sites in cultured cells have a ...
Catalase is an important antioxidant protein which can protect organisms against various oxidative stresses by eliminating hydrogen peroxide. The catalase cDNA of Cristaria plicata@?cpCAT@? was cloned from the haemocytes using degenerate primers by the method of 3' and 5' rapid amplification of cDNA ends PCR. The gene is 4863 bp long and has a total of two introns and three exons. The precise size and location of the introns and exons have been determined. In addition the full-length cDNA of cpCAT contained 2618 bp, The cDNA contained a 5' untranslated region (UTR) of 136 nucleotides, the 3' UTR of 979 bp with a canonical polyadenylation signal sequence AATAAA and a polyA tail, and an open reading frame (ORF) of 1503 bp, encoding 501 amino acid residues with 56.86 kDa predicted molecular w...
Directed evolution of proteins depends on the production of molecular diversity by random mutagenesis. While a number of methods have been developed for introducing this diversity, the best ways to sample it are not always clear. Here we used simple statistics to analyse completeness and diversity in randomized libraries generated by oligonucleotide-directed mutagenesis, error-prone polymerase chain reaction (epPCR) and in vitro recombination of highly homologous sequences. For oligonucleotide-directed mutagenesis, we derive equations to estimate how complete a given library is expected to be and also to predict the size of library required to give a fixed probability of being 100% complete. We describe the statistical bases for computer programs which estimate the number of distinct variants represented in epPCR and shuffled libraries, dubbed PEDEL and DRIVeR, respectively. These programs allow the user to calculate (rather than guess) the ...
The contents of immunoreactive somatostatin (IR-SRIF) and ..beta..-endorphin (IR-..beta..-EP) in 12 brain regions were examined in rats exposed neonatally to propylthiouracil (PTU) through the mother's milk. Since the dose of PTU used in this study is lower than the usual dose employed to induce hypothyroidism, a milder form of neonatal hypothyroidism resulted. This conclusion is supported by the only mild subnormal growth of rats to adulthood and serum T/sub 4/ and T/sub 3/ concentrations in the normal range. Adult rats treated with PTU neonatally had significantly higher IR-SRIF contents in several brain regions compared to controls, whereas IR-..beta..-EP levels were not significantly different in most regions. The results indicate that even mild hypothyroidism during early postnatal development causes permanent impairment of brain function, which manifests itself in part by an altered brain content of IR-SRIF.
Lubricant additives have been known to affect rolling element bearing surface durability for many years. Tapered roller bearings were used in fatigue testing of lubricants formulated with gear oil type additive systems. These systems have sulfur- and phosphoruscontaining compounds used for gear protection as well as bearing lubrication. Several variations of a commercially available base additive formulation were tested having modified sulfur components. The variations represent a range of ''active'' extreme pressure (EP) chemistries. The bearing fatigue test results were compared with respect to EP formulation and test conditions. Inner ring near-surface material in selected test bearings was evaluated on two scales: the micrometer scale using optical metallography and the nanometer scale using transmission electron microscopy (TEM). Focused-ion beam (FIB) techniques were used for TEM specimen preparation. ...
Shewanella oneidensis MR-1 is a model environmental organism that possesses diverse respiratory capacities, including the ability to reduce soluble Cr(VI) to sparingly soluble, less toxic Cr(III). Effective bioremediation of Cr-contaminated sites requires knowledge of the molecular mechanisms and regulation of heavy metal resistance and biotransformation by dissimilatory metal-reducing bacteria. Towards this goal, our ERSP-funded work is focused on the identification and functional analysis of genes/proteins comprising the response pathways for chromate detoxification and/or reduction. Previous transcriptomic profiling and whole-cell proteomic analyses implicated the involvement of a functionally undefined DNA-binding response regulator (SO2426) and a putative azoreductase (SO3585) in the chromate stress response of MR-1. Here we describe a detailed functional analysis of SO2426 and SO3585 in order to begin to understand the role of these proteins in the cellular ...
A computerized corrosion measuring system (EG and G model 350 A) was used to study the influence of Cr, Mo, Ti, Nb and W on the pitting corrosion of nickel base alloys in 3% NaCl at 90"0C. The electrochemical parameters under investigation are the corrosion potential E_c_o_r_r, pitting potential E_p and protection potential E_p_p. The corrosion behaviour of nickel base alloys were studied by using pitting scan and potentiostatic techniques. Values of corrosion potential, pitting potential and protection potential were used for a ranking of alloys for corrosion resistance.
We discuss the search of excited leptons and quarks with spin 1/2 at {gamma}{gamma} and at {gamma}e colliders. We show that {gamma}{gamma} colliders have important advantages for the observation of excited leptons and quarks in comparison with ee, ep, and pp colliders discussed in previous papers. These collisions give a simple test for the chirality of the l{sup *}l{gamma} transition. The anomalous magnetic moment of excited leptons can be observed when its value is not too small. (orig.).
The fatigue properties of EP539LM alloy with an Al-Nb-Si fused slurry coating and a Co-Cr-Al-Y electron-beam coating are investigated experimentally in vacuum and in air at 900 C. It is found that the protective coatings reduce the fatigue life of the specimens both in vacuum and in air, with the electron-beam coating affecting the fatigue life of the alloy to a lesser degree than the fused slurry coating. The negative effect of the coatings on the fatigue life of the alloy is attributed largely to the properties of the coating material. 7 references.
The effective remediation of contaminated sites requires accurate identification of chemical distributions. A rapid sampling method using passive sampling devices (PSDs) can provide a thorough site assessment. We have been pursuing their application in terrestrial systems and have found that they increase the ease and speed of analysis, decrease solvent usage and overall cost, and minimize the transport of contaminated soils. Time and cost savings allow a higher sampling frequency than is generally the case using traditional methods. PSDs have been used in the field in soils of varying physical properties and have been successful in estimating soil concentrations ranging from 1 {mu}g/kg (parts per billion) to greater than 200 mg/kg (parts per million). They were also helpful in identifying hot spots within the sites. Passive sampling devices show extreme promise as an analytical tool to rapidly characterize contaminant distributions in soil. ...
The steroidogenic factor 1 (SF-1, also known as NR5A1) is a transcription factor belonging to the nuclear receptor superfamily. Whereas most of the members of this family have been extensively characterized, the therapeutic potential and pharmacology of SF-1 still remains elusive. Described here is the identification and characterization of selective inhibitory chemical probes of SF-1 by a rational ultra-high-throughput screening (uHTS) strategy. A set of 64,908 compounds from the National Institute of Health's Molecular Libraries Small Molecule Repository was screened in a transactivation cell-based assay employing a chimeric SF-1 construct. Two analogous isoquinolinones, ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-7-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate (SID7969543) and ethyl 2-[2-[2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate and (SID7970631), were identified as ...
The national remediation program in Croatia consists of three stages: (1) identification and characterization of radioactively contaminated sites; (2) preparing activities for restoration; and (3) physical restoration at selected (high-prioritized) sites. The program is coordinated by the APO and, in the first stage, performed by both national research institutes of Ruder Boskovi and Institute for Medical Research and Occupational Health. The program supervisors are Ministry of Health, Ministry of Economy (Department of Energy) and State Administration for Environmental Protection. There were more than thirty sites suspected to be radioactively contaminated in Croatia. They were classified into four contamination type groups: (1) dumps containing contaminated coal slag and ash; (2) dumps containing contaminated phosphates and phospho-gypsum resulting from fertilizers industry; (3) geothermal springs and gas/oil wells; and (4) sites containing ...
Populations living close to high-voltage transmission lines often have residential magnetic field exposures in excess of 1 [mu]T, and sometimes over 2 [mu]T. Yet, populations studied in most epidemiologic investigations of the association between residential magnetic field exposure and cancer typically have exposures below 1 [mu]T and frequently below 0.5 [mu]T. To improve statistical power and precision, it would be useful to compare high exposure populations with low exposure population. Toward this end, we have developed an automated method for identifying populations living near high-voltage transmissions lines. These populations likely have more highly exposed individuals that the population at large. The method uses a geographic information system (GIS) to superimpose digitized transmission line locations on U.S. Census block location data and then extract relevant demographic data. Analysis of data from a pilot study of the population residing within 100 m of a 29-km segment of ...
Available in abstract form only. Full text of publication follows: The application spectrum of X-ray and Gamma radiation is increasing exponentially in the area of diagnostic, nuclear medicine, food preservation, nuclear power plants and strategic utilities. To prevent the harmful effects of these radiations, shielding materials based on lead metal and its compounds are being used historically, which are toxic in nature. To protect environment it has become necessary to develop non-toxic lead free shielding materials. The use of titanium metal and its compounds as synthetic rock i.e. SYNROC are reported to be very effective non-toxic shielding materials for various applications. Red mud waste generated in aluminum producing industries possesses a unique mineralogical compositions containing fairly high quantity of titanium oxide and iron oxide useful for making non toxic shielding compositions and therefore red mud has been utilized for the first time in the world for making radiation ...
Full text: Based on experience with nuclear material confiscated in Hungary from illicit trafficking activities in the nineties it has been decided that traditional gamma-spectrometry should be complemented by destructive analytical techniques. The 17/1996 (I. 31.) Korm. Governmental Decree delegated the identification, categorization and characterization tasks to the Institute of Isotopes, Budapest. Routine gamma-spectrometric methods have been further developed aiming at the i) age (production date) determination of seized samples and complete (nondismountable) uranium-bearing items (such as fresh fuel bundles and fission chambers) by HRGS technique, ii) improvement of measurement accuracy and reliability. Starting in 2005 mass spectrometry (ICP-SFMS) and scanning electron microscopy have been implemented to characterize nuclear samples in more detail and to analyze environmental samples both for isotopic and elemental ...
The Energy Conversion and Storage Program applies chemistry and materials science principles to solve problems in (1) production of new synthetic fuels, (2) development of high-performance rechargeable batteries and fuel cells, (3) development of advanced thermochemical processes for energy conversion, (4) characterization of complex chemical processes, and (5) application of novel materials for energy conversion and transmission. Projects focus on transport-process principles, chemical kinetics, thermodynamics, separation processes, organic and physical chemistry, novel materials, and advanced methods of analysis. Electrochemistry research aims to develop advanced power systems for electric vehicle and stationary energy storage applications. Topics include identification of new electrochemical couples for advanced rechargeable batteries, improvements in battery and fuel-cell materials, and the establishment of engineering principles applicable ...
The Energy Conversion and Storage Program applies chemistry and materials science principles to solve problems in (1) production of new synthetic fuels, (2) development of high-performance rechargeable batteries and fuel cells, (3) development of advanced thermochemical processes for energy conversion, (4) characterization of complex chemical processes, and (5) application of novel materials for energy conversion and transmission. Projects focus on transport-process principles, chemical kinetics, thermodynamics, separation processes, organic and physical chemistry, novel materials, and advanced methods of analysis. Electrochemistry research aims to develop advanced power systems for electric vehicle and stationary energy storage applications. Topics include identification of new electrochemical couples for advanced rechargeable batteries, improvements in battery and fuel-cell materials, and the establishment of engineering principles applicable ...
Terminal-differential algorithm for identification of local nonhomogeneities in items under control is developed on the basis of measurements of X-ray or gamma-radiation weakening. The algorithm may be applied by developing radiation schemes of nondestructive control, identifying inadmissible inclusions in the object under study
Direct identification of group B streptococci from a selective broth medium was performed with the Phadebact streptococcus test to determine the feasibility of this technique for early detection of...Full Text Available
BACKGROUNDAdolescent peer group self-identification refers to adolescents’ affiliation with reputation-based peer groups such as “Goths” or...Full Text Available
Several efforts have been made to completely automate cephalometric analysis by automatic landmark search. However, accuracy obtained was worse than manual identification in every study. The analogue-to-digital...Full Text Available
For identification of genes responsible for varietal differences in flowering time and leaf morphological traits, we constructed a linkage map of Brassica rapa DNA markers including...Full Text Available
... Considering these observations, it is most likely that Brucela proteins involved in protective immunity will preferentially stimulate INF-g producing T ...
The cosmic antiparticle ring imaging Cherenkov experiment (CAPRICE) flew on a stratospheric balloon 8-9 August 1994 over northern Canada and collected data for more than 21 hours with less than 5 g/cm{sup 2} of residual atmosphere. The instrument includes a solid radiator RICH detector and an electromagnetic calorimeter for particle identification in the magnetic spectrometer. Preliminary antiproton and positron identification capabilities are presented.
Experiences with the model parameter identification of the excitation system (EXS) and the power system stabilizer (PSS) for Mingtan{number_sign}6 pumped storage generation unit of Taiwan Power System are presented in this paper. The input-output data corresponding to each block of the EXS and PSS were obtained when the finalization tests of this unit were performed. The generalized least squares (GLS) approach is introduced and employed to identify the desired parameters of the noisy excitation system and PSS models. In this method, the reduction technique of biased estimates due to the non-white (correlated) identification residual is also applied to improve the accuracy of identification. The results of the parameter estimation are satisfactory. The GLS parameter identification method using the measured data at finalization tests is then suggested from the viewpoint of economy and engineering.
Irradiation of EP-823 (16Cr12MoWsiVNbB) ferritic-martensitic steel with 7-MeV Ni++ ions and with 30- and 70-keV He+ ions at a temperature of 500?C was followed by an increase in the microhardness, which was due to both radiation point defects and changes in the phase composition and the dislocation structure of the steel. It was found that the dependence of the largest relative increase in the microhardness on the concentration of radiation-induced point defects in the near-surface region of the steel under irradiation with different ions correlated with an analogous dependence of the surface segregation of silicon and chromium.
The purpose of this study is to investigate the influence of tungsten carbide/carbon (WC/C) coating on the surface durability of casehardened steel gear. Two kinds of WC/C coatings were deposited on the ground gear pair made of chromium molybdenum steel with carburizing and quenching. One is the conventional WC/C coating, and the other is WC/C coating with about 1 ?m CrN interlayer. Here, the WC/C-coated test pinion and the WC/C-coated one with CrN interlayer are represented by WT and ST, respectively. Non-coated test pinion is represented by NT. The surface roughness along the tooth profile direction of WT and ST was almost the same as that of NT. A spur gear test was carried out with an IAE power circulating type gear test rig under EP gear oil lubricating condition. The fatal failure mo...
Measurements have been made of certain parameters relevant to the operation of electron-counting detectors. An experimental chamber consisting of a uniform-field drift tube and a coaxial proportional counter thas been employed to obtain data, at very low drift fields (E/p<0.02 V/cm Torr), on electron mobility and lifetimes in a range of gas mixtures. These mixtures included argon, methane, nitrogen and carbon dioxide. Measurements of single-electron spectra showed that, unexpectedly for the standard gas mixtures employed, useful departure from an exponential spectrum was not possible without the production of cathode secondaries. Although the present studies employed only the counter electrical signal the information obtained should be directly relevant to the operation of practical light-pulse systems. Examples of electron-counting spectra for soft X-rays are shown. (orig.).
Fetal exposure to phthalates may be associated with adverse reproductive effects, including cryptorchidism and decreased semen quality. Information about human placental transfer is needed to qualify the hypotheses. A dual recirculating placenta perfusion system to monitor concentrations of eight phthalate monoesters in fetal and maternal perfusates was established. In addition to perfusate background measures of phthalate monoesters, the concentrations in umbilical cord plasma and placenta tissue were measured. Monomethyl phthalate (mMP), monoethyl phthalate (mEP), monobutyl phthalate (mBP), and mono (2-ethyl-hexyl) phthalate (mEHP) were detected in both maternal and fetal perfusate, demonstrating a release of compounds from tissue or blood to perfusates. The distribution of compounds bet...
It has been recently suggested by Arkani-Hamed, Dimopoulos and Dvali that gravity may become strong at energies not far above the electroweak scale and thus remove the hierarchy problem. Such a scenario can be tested at both present and future accelerators since towers of Kaluza-Klein gravitons and associated scalar fields now play an important phenomenological role. In this paper we examine several processes for their sensitivity to a low scale for quantum gravity including deep inelastic ep scattering at DESY HERA, high precision low energy {nu}N scattering, Bhabha and Mo/ller scattering at linear colliders and both fermion and gluon pair production at {gamma}{gamma} colliders. {copyright} {ital 1999} {ital The American Physical Society}
It has been recently suggested by Arkani-Hamed, Dimopoulos and Dvali that gravity may become strong at energies not far above the electroweak scale and thus remove the hierarchy problem. Such a scenario can be tested at both present and future accelerators since towers of Kaluza-Klein gravitons and associated scalar fields now play an important phenomenological role. In this paper we examine several processes for their sensitivity to a low scale for quantum gravity including deep inelastic ep scattering at DESY HERA, high precision low energy #nu#N scattering, Bhabha and Mo/ller scattering at linear colliders and both fermion and gluon pair production at #gamma##gamma# colliders. copyright 1999 The American Physical Society
It has been recently suggested by Arkani-Hamed, Dimopoulos and Dvali that gravity may become strong at energies not far above the electroweak scale and thus remove the hierarchy problem. Such a scenario can be tested at both present and future accelerators since towers of Kaluza-Klein gravitons and associated scalar fields now play an important phenomenological role. In this paper we examine several processes for their sensitivity to a low scale for quantum gravity including deep inelastic ep scattering at HERA, high precision low energy #nu#N scattering, Bhabha and Moller scattering at linear colliders and fermion pair production at #gamma##gamma# colliders
It has been recently suggested by Arkani-Hamed, Dimopoulos and Dvali that gravity may become strong at energies not far above the electroweak scale and thus remove the hierarchy problem. Such a scenario can be tested at both present and future accelerators since towers of Kaluza-Klein gravitons and associated scalar fields now play an important phenomenological role. In this paper we examine several processes for their sensitivity to a low scale for quantum gravity including deep inelastic ep scattering at HERA, high precision low energy {nu}N scattering, Bhabha and Moller scattering at linear colliders and fermion pair production at {gamma}{gamma} colliders.
Deep inelastic {ital e}{sup {minus}}{ital p} scattering has been studied in both the charged current (CC) and neutral current (NC) reactions at momentum transfers squared {ital Q}{sup 2} above 400GeV{sup 2} using the ZEUS detector at the HERA {ital ep} collider. The CC and NC total cross sections, the NC to CC cross section ratio, and the differential cross sections {ital d}{sigma}/{ital dQ}{sup 2} are presented. From the {ital Q}{sup 2} dependence of the CC cross section, the mass term in the CC propagator is determined to be {ital M}{sub {ital W}}=76{plus_minus}16{plus_minus}13 GeV.
The phased field development of the Lion and Panthere fields, offshore the Ivory Coast, includes a small floating production, storage, and offloading (FPSO) tanker with minimal processing capability as an early oil production system (EPS). For the long-term production scheme, the FPSO will be replaced by a converted jack up mobile offshore production system (MOPS) with full process equipment. The development also includes guyed-caisson well platforms, pipeline export for natural gas to fuel an onshore power plant, and a floating storage and offloading (FSO) tanker for oil export. Pipeline export for oil is a future possibility. This array of innovative strategies and techniques seldom has been brought together in a single project. The paper describes the development plan, early oil, jack up MOPS, and transport and installation.
We compute the corrections from two-photon and {gamma}-Z exchange in parity-violating elastic electron-proton scattering, used to extract the strange form factors of the proton. We use a hadronic formalism that successfully reconciled the earlier discrepancy in the proton's electron to magnetic form factor ratio, suitably extended to the weak sector. Implementing realistic electroweak form factors, we find effects of the order 2%-3% at Q{sup 2} < or approx. 0.1 GeV{sup 2}, which are largest at backward angles and have a strong Q{sup 2} dependence at low Q{sup 2}. Two-boson contributions to the weak axial current are found to be enhanced at low Q{sup 2} and for forward angles. We provide corrections at kinematics relevant for recent and upcoming parity-violating experiments.
We report a search for small RNAs (sRNAs) in the low-GC, gram-positive human pathogen Streptococcus pneumoniae. Based on bioinformatic analyses by Livny et al. (J. Livny, A. Brencic, S. Lory, and M. K. Waldor, Nucleic Acids Res. 34:3484-3493, 2006), we tested 40 candidates by Northern blotting and confirmed the expression of nine new and one previously reported (CcnA) sRNAs in strain D39. CcnA is one of five redundant sRNAs reported by Halfmann et al. (A. Halfmann, M. Kovacs, R. Hakenbeck, and R. Bruckner, Mol. Microbiol. 66:110-126, 2007) that are positively controlled by the CiaR response regulator. We characterized 3 of these 14 sRNAs: Spd-sr17 (144 nucleotides [nt]; decreased in stationary phase), Spd-sr37 (80 nt; strongly expressed in all growth phases), and CcnA (93 nt; induced by competence stimulatory peptide). Spd-sr17 and CcnA likely fold into structures containing single-stranded regions between hairpin structures, whereas Spd-sr37 forms a base-paired ...
The identification and characterization of carbonaceous materials (CMs) that control hydrophobic organic chemical (HOC) sorption is essential to predict the fate and transport of HOCs in soils and sediments. The objectives of this paper are to determine the types of CMs that control HOC sorption in the oxidized and reduced zones of a glacially deposited groundwater sediment in central Illinois, with a special emphasis on the roles of kerogen and black carbon. After collection, the sediments were treated to obtain fractions of the sediment samples enriched in different types of CMs (e.g., humic acid, kerogen, black carbon), and selected fractions were subject to quantitative petrographic analysis. The original sediments and their enrichment fractions were evaluated for their ability to sorb trichloroethene (TCE), a common groundwater pollutant. Isotherm results and mass fractions of CM enrichments were used to calculate sorption contributions of ...
We present differential scanning calorimetry (DSC), X-ray diffractometry, in situ Moessbauer spectroscopy (MS), and transmission electron microscopy (TEM) studies in Metglas ribbons subjected to different heat treatments. The temperature evolution of the hyperfine field H_h_f(T) and the Curie temperature (T_c) of the amorphous phase are determined. The magnetic field originally present in the amorphous phase has a 'normal' behavior, in the sense that it can be described by the Weiss molecular field theory. The total angular momentum of the iron atoms turns out to be 5/2 and this implies Fe"3"+ in which the electronic spins are uncoupled. When the samples are maintained near T_c (#approx#673 K), three new magnetic phases are detected in the Moessbauer spectra, indicating an onset of a crystallization process well below the first crystallization temperature (T_X_1), as determined by DSC (#approx#820 K). The magnetic behavior of these phases is also described by universal Brillouin curves ...
Full text: A novel protocol based on electrospray ionization (ESI) multiple stage high capacity ion trap (HCT) mass spectrometry (MS) was developed for glycosphingolipidomic surveys. The method was optimized for detailed structural elucidation of human brain gangliosides and particularly applied to human hippocampus-associated structures. The multiple stage MS experiments allowed for a complete structural characterization of GM1 ganglioside species, which was achieved by elucidation of the oligosaccharide sequence, identification of the GM1 a structural isomer from the data upon sialic acid localization along the sugar backbone and determination of the d18:1/18:0 of fatty acid/sphingoid base composition of the ceramide moiety. The methodology developed here is of general practical applicability for glycolipids and represents a step forward in the implementation of the advanced and most modern MS methods in glycomics. Gangliosides are ...
The Chediak-Higashi syndrome (CHS) is a severe autosomal recessive condition, features of which are partial oculocutaneous albinism, increased susceptibility to infections, deficient natural killer cell activity, and the presence of large intracytoplasmic granulations in various cell types. Similar genetic disorders have been described in other species, including the beige mouse. On the basis of the hypothesis that the murine chromosome 13 region containing the beige locus was homologous to human chromosome 1, we have mapped the CHS locus to a 5-cM interval in chromosome segment 1q42.1-q42.2. The highest LOD score was obtained with the marker D1S235 (Z{sub max} = 5.38; {theta} = 0). Haplotype analysis enabled us to establish D1S2680 and D1S163, respectively, as the telomeric and the centromeric flanking markers. Multipoint linkage analysis confirms the localization of the CHS locus in this interval. Three YAC clones were found to cover the entire region in a contig established by YAC ...
Owing to exceptional biomolecule preservation, fossil avian eggshell has been used extensively in geochronology and palaeodietary studies. Here, we show, to our knowledge, for the first time that fossil eggshell is a previously unrecognized source of ancient DNA (aDNA). We describe the successful isolation and amplification of DNA from fossil eggshell up to 19 ka old. aDNA was successfully characterized from eggshell obtained from New Zealand (extinct moa and ducks), Madagascar (extinct elephant birds) and Australia (emu and owl). Our data demonstrate excellent preservation of the nucleic acids, evidenced by retrieval of both mitochondrial and nuclear DNA from many of the samples. Using confocal microscopy and quantitative PCR, this study critically evaluates approaches to maximize DNA recovery from powdered eggshell. Our quantitative PCR experiments also demonstrate that moa eggshell has approximately 125 times lower bacterial load than bone, making it a highly ...
Environmental regulatory requirements at both the state and federal level are constantly changing, making it difficult for industry and R ampersand D program managers to project future compliance requirements and costs. Even if a company is trying to keep abreast of various proposed regulatory initiatives, the number of possible combinations of initiatives that could occur in the future seems virtually limitless. Uncertainty associated with potential future environmental compliance requirements makes the identification and evaluation of future investment and R ampersand D opportunities exceedingly difficult, and makes the process of systematic strategic planning increasingly complex. This paper describes a methodology for accounting for uncertain future environmental compliance costs in a systematic, comprehensive manner. Through analysis of proposed initiatives for making future environmental requirements more stringent, forecasting the likelihood of occurrence ...
Human Reliability Analysis (HRA) is a very important part of Probabilistic Risk Analysis (PRA), and constant work is dedicated to improving methods, guidance and data in order to approach realism in the results as well as looking for ways to use these to reduce accident frequency at plants. Further, in order to advance in these areas, several HRA studies are being performed globally. Mexico has participated in the International HRA Empirical study with the objective of -benchmarking- HRA methods by comparing HRA predictions to actual crew performance in a simulator, as well as in the empirical study on a US nuclear power plant currently in progress. The focus of the first study was the development of an understanding of how methods are applied by various analysts, and characterize the methods for their capability to guide the analysts to identify potential human failures, and associated causes and performance shaping factors. The HRA benchmarking study has been ...
There are many methods for introducing random mutations into nucleic acid sequences. Previously, we described a suite of programmes for estimating the completeness and diversity of randomized DNA libraries generated by a number of these protocols. Our programmes suggested some empirical guidelines for library design; however, no information was provided regarding library diversity at the protein (rather than DNA) level. We have now updated our web server, enabling analysis of translated libraries constructed by site-saturation mutagenesis and error-prone PCR (epPCR). We introduce GLUE-Including Translation (GLUE-IT), which finds the expected amino acid completeness of libraries in which up to six codons have been independently varied (according to any user-specified randomization scheme). We provide two tools for assisting with experimental design: CodonCalculator, for assessing amino acids corresponding to given randomized codons; and AA-Calculator, for finding ...
DOI: http://dx.doi.org/10.1103/PhysRevC.78.045209 The helicity amplitudes of the electroexcitation of the Roper resonance are extracted for 1.7 < Q2 < 4.5 GeV2 from recent high precision JLab-CLAS cross section and longitudinally polarized beam asymmetry data for pi+ electroproduction on protons at W=1.15-1.69 GeV. The analysis is made using two approaches, dispersion relations and a unitary isobar model, which give consistent results. It is found that the transverse helicity amplitude A_{1/2} for the gamma* p -> N(1440)P11 transition, which is large and negative at Q2=0, becomes large and positive at Q2 ~ 2 GeV2, and then drops slowly with Q2. The longitudinal helicity amplitude S_{1/2}, which was previously found from CLAS ep -> eppi0,enpi+ data to be large and positive at Q2=0.4,0.65 GeV2, drops with Q2. Available model predictions for gamma* p -> N(1440)P11 allow us to conclude that these results provide strong evidence in favor of ...
In this thesis a study is made of the of voltage characteristics and reactive power control in the transmission network of the Electric Power Systems (EPS) with static compensators of VARs (SCVs). The necessity of voltage and reactive power control and the application of SCVs as a solution means for three representative operation stages of the EPS, considering balanced operation conditions and fundamental frequency is analyzed: Operation in the presence of incremental voltage changes, quasi-stationary operation or steady state and behavior at the occurrence of big disturbances. The application of SCVs to systems of integral transmission is in general a closed loop control system, reason why the analysis of the interaction of the system EPS-SCV is considered as an essential part of the voltage and reactive power control study. Firstly, the response analysis of the control loop is made for incremental voltage changes, ...
This report aims at presenting a view upon uncertainty analysis of phenomenological models with an emphasis on the identification and documentation of various types of uncertainties and assumptions in the modelling of the phenomena. In an uncertainty analysis, it is essential to include and document all unclear issues, in order to obtain a maximal coverage of unresolved issues. This holds independently on their nature or type of the issues. The classification of uncertainties is needed in the decomposition of the problem and it helps in the identification of means for uncertainty reduction. Further, an enhanced documentation serves to evaluate the applicability of the results to various risk-informed applications. (au)
Supplementing the collection of artificial neural network methodologies devised for monitoring energy producing installations, a general regression artificial neural network is proposed for the identification of the two-phase flow that occurs in the coolant channels of boiling water reactors. The utilization of a limited number of image features derived from radiography images affords the proposed approach with efficiency and non-invasiveness. Additionally, the application of counter-clustering to the input patterns prior to training accomplishes an 80% reduction in network size as well as in training and test time. Cross-validation tests confirm accurate on-line flow regime identification.
Supplementing the collection of artificial neural network methodologies devised for monitoring energy producing installations, a general regression artificial neural network is proposed for the identification of the two-phase flow that occurs in the coolant channels of boiling water reactors. The utilization of a limited number of image features derived from radiography images affords the proposed approach with efficiency and non-invasiveness. Additionally, the application of counter-clustering to the input patterns prior to training accomplishes an 80% reduction in network size as well as in training and test time. Cross-validation tests confirm accurate on-line flow regime identification.
The identification of individuals at risk for Alzheimer's disease (AD) is essential for the timely administration of treatment approaches aimed at slowing the onset or progression of the disease....Full Text Available
There is considerable evidence to suggest that the identification and treatment of dyslipidaemia will reduce the risk of premature CHD, i.e. before the age of 65. Diagnosis of the cause of raised plasma...Full Text Available
Impedance Noise Identification is an in-situ method of measuring battery impedance as a function of frequency using a random small signal noise excitation source. Through a series of auto- and cross-correlations and Fast Fourier Transforms, the battery complex impedance as a function of frequency can be determined. The results are similar to those measured under a lab-scale electrochemical impedance spectroscopy measurement. The lab-scale measurements have been shown to correlate well with resistance and power data that are typically used to ascertain the remaining life of a battery. To this end, the Impedance Noise Identification system is designed to acquire the same type of data as an on-board tool. A prototype system is now under development, and results are being compared to standardized measurement techniques such as electrochemical impedance spectroscopy. A brief description of the Impedance Noise Identification ...
Pork identification in four types of food products, which are sausages and the casings, bread and biscuits, using species-specific polymerase chain reaction (PCR) detection of a conserved region in the mitochondrial (mt) 12S ribosomal RNA (rRNA) gene was developed. Genomic DNA of the food products were successfully extracted except for the casing samples, where no genomic DNA was detected. The extracted genomic DNA was then subjected to PCR amplification targeting the specific regions of the 12S rRNA gene. The genomic DNA from the food products were found to be of good quality and produced clear PCR products on the amplification of 12S rRNA gene of 387 base pairs (bp) from pork species. The species-specific PCR identification yielded excellent results for identification of pork derivatives...
... a given ternary molten salt system under conditions which are greatly " different than the normal method of potentiometric titration, that is, high ...
Contractile vacuole complexes are critical components of cell volume regulation and have been shown to have other functional roles in several free-living protists....Full Text Available
ground strike hazards 3) Advancements in the initialization of numerical weather prediction models through better identification of deep convection 4) Improved routing of...
The management of risks of explosives are described. Administrative and procedural controls are considered. The safety management plan involves hazard identification, risk analysis, assessment and control. The current position of explosives safety is considered. 4 tabs.
Advances in modern neuroscience require the identification of principles that connect different levels of experimental analysis, from molecular mechanisms to explanations of cellular functions,...Full Text Available
The CKK-70 400/200 NN telephone exchange in the Nowa Ruda mine in Lower Silesia was used with the JAUL-CAMAC linear subscriber system. The CKK-70 telephone exchanges were supplied without a system for identification of calling subscribers at the ground surface. A modified identification system developed by the Nowa Ruda mine for identifying calling subscribers is evaluated. Its design is shown in 2 schemes and operation is discussed. The identification system was tested over 6 years. Tests showed it to be reliable and uncomplicated. The modified system for identification of calling subscribers adapted for conditions of underground coal mines has been tested in other mines (1 Maj, Piast, Knurow and Staszic). Recommendations for use of the modified system are made.
Ether extracts of cultures of 29 strains representing 6 species of Bacillus, and of individual strains of Escherichia coli, Aerobacter aerogenes, and Pseudomonas...Full Text Available
The main aim of DNA barcoding is to establish a shared community resource of DNA sequences that can be used for organismal identification and taxonomic clarification. This approach was successfully...Full Text Available
BackgroundFunction exertion of specific proteins are key factors in disease progression, thus the systematical identification of those specific proteins is a prerequisite to understand...Full Text Available
A method and apparatus for determining the condition of tissue or otherwise making chemical identifications includes exposing the sample to a light source, and using a synchronous luminescence system to produce a spectrum that can be analyzed for tissue condition.
Chemically reactive compounds in tissues can be monitored through their products of reaction with biomacromolecules. For the purpose of in vivo dose monitoring, hemoglobin (Hb) has been preferred to...Full Text Available
System identification refers to estimation of process parameters and is a necessity in control theory. Physical systems usually have varying parameters. For such processes, accurate identification is particularly important. Online identification schemes are also needed for designing adaptive controllers. Real processes are usually of fractional order as opposed to the ideal integral order models. In this paper, we propose a simple and elegant scheme of estimating the parameters for such a fractional order process. A population of process models is generated and updated by particle swarm optimization (PSO) technique, the fitness function being the sum of squared deviations from the actual set of observations. Results show that the proposed scheme offers a high degree of accuracy even when the observations are corrupted to a significant degree. Additional schemes to improve the accuracy still further are also proposed and ...
This report presents criteria for the identification and evaluation of fire hazards in nuclear power stations. The report presents criteria that are consistent with the existing regulatory approach in Canada, and outlines engineering tools and analytical techniques currently available to deterministically analyse fire. The criteria presented cover the topics which should be included in a fire hazard analysis and provide details of each topic so that the accuracy of an analysis may be evaluated.
Highlights of the meeting are briefly summarized in this paper. Most of the papers presented at the meeting dealt with remediation and pollution prevention practices. A major focus of the technical sessions was on the identification of pollution sources. Identification of exposures to specific chemicals with disease outcomes was also discussed. Other papers focused on ecological exposures and their effects on wildlife to identify the presence of contaminants. 4 refs.
such as public utilities, waste disposal sites, large energy dependent facilities including factories, institutions ( ...provides immediate identification of PCB wastes, informs company officials of any special handling or disposal techniques ...provides immediate identification of PCB wastes, informs company officials of any special handling or disposal techniques
This Standards/Requirements Identification Document (S/RID) sets forth the Environmental Safety and Health (ESH) standards/requirements for the Plutonium Finishing Plant (PFP). This S/RID is applicable to the appropriate life cycle phases of design, construction, operation, and preparation for decommissioning. These standards/requirements are adequate to ensure the protection of the health and safety of workers, the public, and the environment.
A new method of particle identification of heavy ions through the measurement of the Bragg curve centroid and particle energy has been developed using a gas ionization chamber with a resistive anode layer. Z-resolutions comparable to the conventional ..delta..E-E counter telescope could be rather easily attained.
A new method of particle identification of heavy ions through the measurement of the Bragg curve centroid and particle energy has been developed using a gas ionization chamber with a resistive anode layer. Z-resolutions comparable to the conventional #DELTA#E-E counter telescope could be rather easily attained. (orig.).
A new article identification method based on the measurement of Bragg-curve centroids using a gas-filled ionization chamber has been improved for detection of low-energy particles around 1 MeV per nucleon by introducing a nonuniform distribution of resistance on the anode electrode. Almost the same quality of Z-resolutions as in the conventional ..delta..E-E method could be obtained up to Z=19.
Projectilelike fragments following the 80 MeV /sup 16/O+/sup 27/Al reaction have been detected using a Bragg-curve spectroscopy ionization chamber (BCS-IC). The atomic number is deduced from the Bragg-peak amplitude. Nitrogen isotopes are clearly resolved using either range or energy loss data. This is the first application of the BCS method for complete ion identification in a heavy-ion-induced reaction.
Projectilelike fragments following the 80 MeV "1"6O+"2"7Al reaction have been detected using a Bragg-curve spectroscopy ionization chamber (BCS-IC). The atomic number is deduced from the Bragg-peak amplitude. Nitrogen isotopes are clearly resolved using either range or energy loss data. This is the first application of the BCS method for complete ion identification in a heavy-ion-induced reaction.
An improved hydrocarbon fuel is described selected from the group consisting of gasoline, diesel fuel, kerosene, jet fuel, No. 1 heating oil, and No. 2 heating oil containing a detectable amount of one or more fullerene additives therein serving as identification means for said fuel wherein said fullerenes are present in an amount insufficient to alter any of the combustion properties of the fuel.
This document, the Standards/Requirements Identification Document (S/RID) Phase I Assessment Report for the subject facility, represents the results of an Administrative Assessment to determine whether S/RID requirements are fully addressed by existing policies, plans or procedures. It contains; compliance status, remedial actions, and an implementing manuals report linking S/RID elements to requirement source to implementing manual and section.
The sensitivity and specificity of the MGIT TBc identification (TBc ID) test for Mycobacterium tuberculosis complex (MTC) detection in positive Bactec MGIT cultures were 95.2% and 99.2%, respectively. When MTC-positive results obtained from two additional molecular methods were included, the sensitivity of the MGIT TBc ID test was 85.4%, while that of culture was 95.7%. PMID:21450949
1-Naphthylphthalamic acid (NPA) is a specific inhibitor of polar auxin transport that blocks carrier-mediated auxin efflux from plant cells. To allow identification of the NPA receptor thought to be...Full Text Available
In this work a comprehensive metallophysical study was carried out for two aluminosilicide slip coatings of the systems Al-Si and Al-Nb-Si and an electron-beam Co-Cr-Al-Y coating on alloy EP-539 (17...19% Cr, 4...6% Co, 2.5...4% W, 4.5...6.5% Mo, 2...3% Ti, 3...4% Al, 1.4...2% Nb, balance Ni) after high-temperature testing. The protective properties of the coatings were evaluated from the results of laboratory tests for heat resistance at 1000/sup 0/C in the combustion products of diesel fuel with added sulfur at 970, 1000, and 1060/sup 0/C for 100 h and after full-scale tests for 150, 250, 400, and 700 h. Metallographic, hardness, x-ray, and micro x-ray studies of the coating were carried out. Layer-by-layer phase composition and the lattice spacing of the main phases were determined. X-ray analysis was carried out in an a DRON-1 diffractometer in copper K/sub ..-->../-radiation, and x-ray microanalysis was carried out in a MS-46 Cameca microanalyzer
Fetal exposure to phthalates may be associated with adverse reproductive effects, including cryptorchidism and decreased semen quality. Information about human placental transfer is needed to qualify the hypotheses. A dual recirculating placenta perfusion system to monitor concentrations of eight phthalate monoesters in fetal and maternal perfusates was established. In addition to perfusate background measures of phthalate monoesters, the concentrations in umbilical cord plasma and placenta tissue were measured. Monomethyl phthalate (mMP), monoethyl phthalate (mEP), monobutyl phthalate (mBP), and mono (2-ethyl-hexyl) phthalate (mEHP) were detected in both maternal and fetal perfusate, demonstrating a release of compounds from tissue or blood to perfusates. The distribution of compounds between perfusate, umbilical cord plasma, and tissue was in accordance with the physical-chemical properties of the compounds. Results from the present study of compounds residing in ...
A KEK-PS experiment E337 `Angular correlation of intermediate mass fragments emitted from the target multifragmentation reactions with 12 GeV protons` is an extension of the E288 performed a few years ago. The E288 revealed that the proton-induced target multifragmentation reactions at 12 GeV showed quite interesting phenomena such as 70 degree peaking angular distributions for intermediate mass fragments. In December, 1955, the test experiment with 12 GeV protons was started at KEK using this newly constructed counter array of 37 Bragg Curve Counters. The main production experiment was performed in April and May in 1996 after debugging the new counter system and DAQ system, as well as EP1-B beam line. Data with Au, Tm, Sm and Ag targets were successfully accumulated. The data are in the analysis stage, and several interesting features of high energy nuclear reactions have already been seen. (G.K.)
Differential cross sections for 201.5 MeV proton scattering form "8"8Sr were measured. From the analysis of the elastic data, no unique optical-model potential could be obtained, but the radial moments are well determined. In a macroscopic analysis of the collective states it turns out that if the optical potential and transition potential are chosen consistently, unambiguous potential deformation lengths can be obtained even though the optical potential is not unique. Taking into account the range and density dependence of the underlying effective interaction reliable neutron deformation lengths can be obtained. For inelastic transitions of various character microscopic distorted-wave calculations with a density-dependent interaction based on the Paris potential were performed. The nuclear structure was taken from one broken-pair calculations in a large model space, calibrated by (e,e') data. In general a good description is obtained for states with spins ranging from 2"+ to 10"-. ...
Semi-inclusive pi+ electroproduction on protons has been measured with the CLAS detector at Jefferson Lab. The measurement was performed on a liquid-hydrogen target using a 5.75 GeV electron beam. The complete five-fold differential cross sections were measured over a wide kinematic range in Q2, x, z, and pT and over the complete range of azimuthal angles, phi, enabling us to separate the different structure functions, H2+eps*H1, H3 and H4. Our measurements of H2 at low-x were found to be in fairly good agreement with pQCD calculations, suggesting a precocious factorization of the process. Indeed, the conventional f(x)*D(z) term can account for almost all of the observed cross section, even at small z. The measured xF-distributions are in qualitative agreement with high energy data, which suggests a surprising numerical similarity between the spectator diquark fragmentation in the present reaction and the anti-quark fragmentation measured in e+e- collisions. We ...
The reaction of the chelating ligands (obtained by the condensation of 2-hydroxy-1-naphthaldehyde with various primary amines) with [RuHCl(CO)(EPh3)2(B)] (where E=P; B=PPh3, py or pip: E=As; B=AsPh3) in benzene afforded new stable ruthenium(II) carbonyl complexes of the general formula [Ru(Cl)(CO)(EPh3)(B)(L)] (L=anion of bidentate Schiff bases). The structure of the new complexes was investigated using elemental analyses, spectral (FT-IR, UV-vis and 1H NMR) and electrochemical studies and is found to be octahedral. All the metal complexes exhibit characteristic MLCT absorption and luminescence bands in the visible region. The luminescence efficiency of the ruthenium(II) complexes was explained based on the ligand environment around the metal ion. These complexes catalyze oxidation of prim...
The authors studied the resolution of racemic glycidol through esterification with butyric acid catalyzed by porcine pancreatic lipase in organic media. A screening of seven solvents (log P values between 0.49 and 3.0, P being the n-octanol-water partition coefficient of the solvent) showed that neither log P nor the logarithm of the molar solubility of water in the solvent provides good correlations between enantioselectivity and the properties of the organic media. Chloroform was one of the best solvents as regards the enantiometic purity (e.p.) of the ester produced. In this solvent, the optimum temperature for the reaction was determined to be 35C. The enzyme exhibited maximum activity at a water content of 13 [plus minus] 2% (w/w). The enantiomeric purity obtained was 83 [plus minus] 2% of (S)-glycidol butyrate and did not depend on the alcohol concentration or the enzyme water content for values of these parameters up to 200 mM and 25% (w/w), respectively. ...
Oil and gas companies operate in many countries around the world. Their exploration and production (E&P) operations generate many kinds of waste that must be carefully and appropriately managed. Some of these wastes are inherently part of the E&P process; examples are drilling wastes and produced water. Other wastes are generic industrial wastes that are not unique to E&P activities, such as painting wastes and scrap metal. Still other wastes are associated with the presence of workers at the site; these include trash, food waste, and laundry wash water. In some host countries, mature environmental regulatory programs are in place that provide for various waste management options on the basis of the characteristics of the wastes and the environmental settings of the sites. In other countries, the waste management requirements and authorized options are stringent, even though the infrastructure to meet the requirements may not be available yet. In some cases, ...
The ep{yields}e'p{rho}{sup 0} reaction has been measured using the 5.754 GeV electron beam of Jefferson Lab and the CLAS detector. This represents the largest ever set of data for this reaction in the valence region. Integrated and differential cross-sections are presented. The W, Q{sup 2} and t dependences of the cross-section are compared to theoretical calculations based on the t-channel meson-exchange Regge theory, on the one hand, and on quark handbag diagrams related to Generalized Parton Distributions (GPDs) on the other hand. The Regge approach can describe at the {approx}30% level most of the features of the present data while the two GPD calculations that are presented in this article which succesfully reproduce the high-energy data strongly underestimate the present data. The question is then raised whether this discrepancy originates from an incomplete or inexact way of modelling the GPDs or the associated hard scattering amplitude or whether ...
In this review, we show how advances in the theory of magnetic pseudodifferential operators (magnetic $\\Psi$DO) can be put to good use in space-adiabatic perturbation theory (SAPT). As a particular example, we extend results of [PST03] to a more general class of magnetic fields: we consider a single particle moving in a periodic potential which is subjectd to a weak and slowly-varying electromagnetic field. In addition to the semiclassical parameter $\\eps \\ll 1$ which quantifies the separation of spatial scales, we explore the influence of additional parameters that allow us to selectively switch off the magnetic field. We find that even in the case of magnetic fields with components in $C_b^{\\infty}(\\R^d)$, e. g. for constant magnetic fields, the results of Panati, Spohn and Teufel hold, i.e. to each isolated family of Bloch bands, there exists an associated almost invariant subspace of $L^2(\\R^d)$ and an effective hamiltonian which generates the dynamics ...
A simple analytical/numerical model has been developed for computing the evolution, over periods of up to a few hours, of the current and temperature profile in the upper layer of the ocean. The model is based upon conservation laws for heat and momentum, and employs an eddy diffusion parameterisation which is dependent on both the wind speed and the wind stress applied at the sea surface. Other parameters such as the bulk-skin surface temperature difference and CO$_2$ flux are determined by application of the Molecular Oceanic Boundary Layer Model (MOBLAM) of Schluessel and Soloviev. A similar model, for the current profile only, predicts a temporary increase in wave breaking intensity and decrease in wave height under conditions where the wind speed increases suddenly, such as, for example, during gusts and squalls. The model results are compared with measurements from the lagrangian Skin Depth Experimental Profiler (SkinDeEP) surface profiling instrument made ...
The 2- and 8-azido trimer 5'-triphosphate photoprobes of 2-5A have been enzymatically synthesized from [#gamma#-"3"2P]2-azidoATP and [#alpha#-"3"2P]8-azidoAPT by 2-5A synthetase from rabbit reticulocyte lysates. Identification and structural determination of the 2- and 8-azido adenylate trimer 5'-triphosphates were accomplished by enzymatic hydrolyses with T2 RNase, snake venom phosphodiesterase, and bacterial alkaline phosphatase. Hydrolysis products were identified by HPLC and PEI-cellulose TLC analyses. The 8-azido photoprobe of 2-5A displaces p_3A_4["3"2P]pCp from RNase L with affinity equivalent to p_3A_3. The 8-azido photoprobe also activates RNase L to hydrolyze poly(U)["3"2P]pCp 50% at 7 /times/ 10/sup /minus/9/ M in core-cellulose assays. The 2- and 8-azido photoprobes and authentic p_3A_3 activate RNase L to cleave 28S and 18S rRNA to specific cleavage products at 10/sup /minus/9/ M in rRNA cleavage assays. The nucleotide binding site(s) of RNase L and/or ...
On the basis of cylindrical roller thrust bearings it was systematically examined to what extent PVD-coatings are able to take over the function of EP/AW-additives. The bearings were tested under heavy-duty conditions in order to distinguish very fast the efficiency of different coating-substrate-systems. Several coatings were tested for their ability to protect an un-coated counterpart. So just the washers of the roller bearings were coated, the rollers stayed un-coated. Four Me-C:H-coatings showed the best performance and fulfilled the required criterion for roller bearings in the boundary friction: low loss of mass and hardly surface deviation. Material carryover from the carbonaceous coating to the 100Cr6 steel surface was developed by the Me-C:H-coatings during the tests. This mechanism was able to protect the un-coated rollers. Closer investigations were done with an ESMA analysis (electron beam micro range analysis) on ZrC{sub g}-coatings. It could be seen, ...
We report on a recent search for {bar {nu}}{sub e} appearance from stopped {pi}{sup +} {yields} {mu}{sup +}{nu}{sub {mu}} and {mu}{sup +} {yields} e{sup +}{nu}{sub e}{bar {nu}}{sub {mu}} decay made by the LAMPF experiment E645. The appearance of {bar {nu}}{sub e} may occur from {bar {nu}}{sub {mu}} {yields} {bar {nu}}{sub e}, {nu}{sub e} {yields} {bar {nu}}{sub eL}, or {nu}{sub {mu}} {yields} {bar {nu}}{sub eL} oscillations. Appearance may also occur from rare {mu}{sup +} {yields} e{sup +}{bar {nu}}{sub e}{nu}{sub {mu}} decay, which is allowed by a multiplicative lepton charge conservation law. The neutrino energies range from E{sub {nu}} = 0 to 52.8MeV. The neutrino detector, which is located 26.1 meters from the neutrino source, consists of a segmented liquid scintillator and proportional drift tube central detector surrounded by both active and passive shielding. The central detector detects {bar {nu}}{sub e} through the {bar {nu}}{sub e}p {yields} ne{sup +} ...
The purposes of this report are (1) to perform a Verification and Validation (V and V) test for the VIPEX(Vital-area Identification Package EXpert) software and (2) to improve a software quality through the V and V test. The VIPEX was developed in Korea Atomic Energy Research Institute (KAERI) for the Vital Area Identification (VAI) of nuclear power plants. The version of the VIPEX which was distributed is 3.2.0.0. The VIPEX was revised based on the first V and V test and the second V and V test was performed. We have performed the following tasks for the V and V test on Windows XP and VISTA operating systems: ? Testing basic functions including fault tree editing ? Testing all kind of functions ? Research for update from Visual BASIC 6.0 to Visual BASIC 2008
This paper deals with the experimental identification and the validation of a non-parametric probabilistic approach allowing model uncertainties and data uncertainties to be taken into account in the numerical model developed to predict low- and medium-frequency dynamics of structures. The analysis is performed for a composite sandwich panel representing a complex dynamical system which is sufficiently simple to be completely described and which exhibits, not only data uncertainties, but above all model uncertainties. The dynamical identification is experimentally performed for eight panels. The experimental frequency response functions are used to identify the non-parametric probabilistic approach of model uncertainties. The prediction of the low- and medium-frequency dynamical responses obtained with the stochastic system is compared with the experimental measurements.
This paper presents a dynamic displacement influence line method for moving load identification on bridge. The finite element model of Poyang Lake continuous truss bridge-train systems is established and the dispersed modal shapes are acquired by modal analysis. Multi-axle moving train loads are identified with simulated annealing genetic algorithm by minimizing the errors between the measured displacements and the reconstructed displacements from the identified moving loads. In the identification process, the dynamic displacement influence line technique is used to calculate the time history displacement responses of the bridge to avoid solving equations of motion of the bridge repetitively. Several important parameters of the bridge-train system are discussed to investigate their effects...
This contribution deals with identification of fractional-order dynamical systems. System identification, which refers to estimation of process parameters, is a necessity in control theory. Real processes are usually of fractional order as opposed to the ideal integral order models. A simple and elegant scheme of estimating the parameters for such a fractional order process is proposed. This method employs fractional calculus theory to find equations relating the parameters that are to be estimated, and then estimates the process parameters after solving the simultaneous equations. The said simultaneous equations are generated and updated using particle swarm optimization (PSO) technique, the fitness function being the sum of squared deviations from the actual set of observations. The data used for the calculations are intentionally corrupted to simulate real-life conditions. Results show that the proposed scheme offers a very high degree of ...
BackgroundA common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs requires...Full Text Available
Alkylphenols are widely used as plastic additives and surfactants. We report the identification of an alkylphenol, nonylphenol, as an estrogenic substance released from plastic centrifuge tubes. This...Full Text Available
Objective:The identification of biological markers in order to assess different aspects of COPD is an area of growing interest. The objective of this study was to investigate whether...Full Text Available
BackgroundStrategies to accurately identify the occurrence of specific health care events in administrative data is central to many quality improvement and research efforts. Many...Full Text Available
Oligonucleotide DNA probes complementary to the hypervariable region of the 16S rRNA of Bacteroides forsythus were tested for their specificity and sensitivity against reference and clinical isolates...Full Text Available
In proteomics, one-dimensional (1D) SDS-PAGE is widely used for protein fractionation prior to mass spectrometric analysis to enhance dynamic range of analysis and to improve identification...Full Text Available
Rhizobium leguminosarum, biovar viceae, strain RCC1001 contains two glutamine synthetase activities, GSI and GSII. We report here the identification of glnA, the structural gene for GSI. A 2 kb fragment...Full Text Available
This note is about three interesting 15th and 16th century sightings of comets in Kashmiri chronicles. We provide reasons for their identification as the 1468 S1, 1531 (Halley's), and 1533 M1 comets.
BackgroundAKXD recombinant inbred strains of mice have proven to be very useful in the identification of potential oncogenes and tumor suppressors involved in the development of...Full Text Available
Accompanying rapid developments in hepatic surgery, the number of surgeries and identifications of histological types of primary hepatic space-occupying lesions (PHSOLs) have increased dramatically....Full Text Available
Sparganosis is a rare parasitic infection affecting various organs, including the central nervous system, especially the lumbar epidural space. This report describes the identification of disease and...Full Text Available
MIL-STD-129. N. 5/15/97. Standard Practice for Military Marking. MIL-STD-130. K. 1/15/00. Identification Marking of U.S. Military Property. MIL-STD-2073-1 ...
The aspirin esterase activity of human plasma is due to butyrylcholinesterase and albumin. Our goal was to identify the amino acid residues involved in the aspirin esterase activity of albumin....Full Text Available
Genomic disorders are conditions that result from DNA rearrangements, such as deletions or duplications. The identification of the dosage-sensitive gene(s) within the rearranged genomic interval is...Full Text Available
The past decade has seen rapid advances in the identification of associations between candidate genes and a range of common multifactorial disorders. This paper evaluates public attitudes towards the...Full Text Available
BackgroundTissue microarray (TMA) data are commonly used to validate the prognostic accuracy of tumor markers. For example, breast cancer TMA data have led to the identification...Full Text Available
Standard Practice for Military Marking. MIL-STD-130. K. 1/15/00. Identification Marking of U.S. Military Property. MIL-STD-2073-1 D. Notice 1. 12/15/99. 05/10/ 02 ...
Thirty chemicals or substances currently undergoing long-term carcinogenicity bioassays in rodents have been used in a project to further evaluate methods and information that may have the capability...Full Text Available
Skin sensitization is the most commonly reported occupational illness, causing much suffering to a wide range of people. Identification and labeling of environmental allergens is urgently required to...Full Text Available
BackgroundIdentification of urinary biomarkers for detection of bladder cancer recurrence would be beneficial to minimize the frequency of cystoscopy. Our objective was to determine...Full Text Available
The genus of filamentous cyanobacteria, Lyngbya, has been found to be a rich source of bioactive metabolites. However, identification of such compounds from Lyngbya...Full Text Available
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor survival. The identification of therapeutic targets is essential to improving outcomes. Previous studies found that expression...Full Text Available
Experience with visual objects leads to later improvements in identification speed and accuracy (“repetition priming”), but generally leads to reductions in neural activity in single-cell...Full Text Available
BackgroundThe lack of adequate randomized clinical trials (RCT) has hindered identification of new therapies that are safe and effective for patients with primary focal segmental...Full Text Available
OBJECTIVE—Identification of arterial genes and pathways altered in obesity and diabetes.RESEARCH DESIGN AND METHODS—Aortic gene expression profiles of...Full Text Available
Mycobacterium tuberculosis is the etiologic agent of tuberculosis and can be accurately detected by laboratories using commercial genetic tests. Nontuberculosis mycobacteria (NTM) causing other mycobacterioses...Full Text Available
Motivation: The identification of gene regulatory modules is an important yet challenging problem in computational biology. While many computational methods have been proposed to identify...Full Text Available
BackgroundThe binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitopes...Full Text Available
Genes of the S100 fused-type protein (SFTP) family are clustered within the epidermal differentiation complex and encode essential components that maintain epithelial homeostasis and barrier functions....Full Text Available
BackgroundIdentification of global livestock diversity hotspots and their importance in diversity maintenance is essential for making global conservation efforts. We screened 52...Full Text Available
BackgroundNeuropeptide Y is a key neurotransmitter of the central nervous system which plays a vital role in the feed energy homeostasis in mammals. Mutations in the regulatory and...Full Text Available
The identification of predictive biomarkers is at the core of modern toxicology. So far, a number of approaches have been proposed. These rely on statistical inference of toxicity response from either...Full Text Available
A novel approach to the Bragg curve spectroscopy is utilized to construct a charged particle detector which makes fragment elemental identification and energy measurement possible. The advantage of the construction includes good timing and spectroscopic properties with a very low energy threshold. ((orig.))
BackgroundGene expression profiling and the analysis of protein-protein interaction (PPI) networks may support the identification of disease bio-markers and potential drug targets....Full Text Available
Portuguese ... Orig. Title Isolamento e identificacao do flavonoide (-)-4'-metil-epigalocatequina das raizes de Maytenus obtusifolia Mart. (Celastraceae)
A light-sensitive vitamin B12 derivative has been extracted from the adult cestode, Spirometra mansonoides. This corrinoid was identified as the cobamide coenzyme, adenosylcobalamin, by its chromatographic, chemical, and spectral properties. PMID:1003284
The identification and validation of biomarkers for diagnosing Alzheimer's disease (AD) and other forms of dementia are increasingly important. To date, ELISA measurement of β-amyloid(1–42),...Full Text Available
Simian retroperitoneal fibromatosis (RF) is a vascular fibroproliferative neoplasm which has many morphological and histological similarities to human Kaposi's sarcoma (KS). Like epidemic KS in AIDS...Full Text Available
Francisella tularensis is a highly infectious bacterium causing the zoonotic disease tularaemia. During its infectious cycle, F. tularensis is not only exposed to the...Full Text Available
Various methods to analyse the effect of a non-isotherme water injection on the pressure evolution during a test on a double geothermal well are investigated. Then, several types of injection test are simulated with experimental data to examine the condit...
Understanding the interactions between herpesviruses and their host cells and also the interactions between neoplastically transformed cells and the host immune system is fundamental to understanding...Full Text Available
Isogenic strains containing insertional disruptions of 10 Haemophilus influenzae Rd genes were investigated for their effects on the susceptibility of the organism to various classes...Full Text Available
The plasmid pE194 (3.7 kilobases) is capable of integrating into the genome of the bacterial host Bacillus subtilis in the absence of the major homology-dependent RecE recombination system. Multiple...Full Text Available
IntroductionThe murine air pouch is a bursa-like space that resembles the human synovial membrane. Injection of monosodium urate (MSU) crystals into the pouch elicits an acute inflammatory...Full Text Available
BackgroundDNA repair is the general term for the collection of critical mechanisms which repair many forms of DNA damage such as methylation or ionizing radiation. DNA repair has...Full Text Available
Auxin modulates diverse plant developmental pathways through direct transcriptional regulation and cooperative signaling with other plant hormones. Genetic and biochemical approaches have clarified...Full Text Available
BackgroundMastitis in dairy cattle results from infection of mammary tissue by a range of micro-organisms but principally coliform bacteria and Gram positive bacteria such as Staphylococcus...Full Text Available
Over 200 mutations in the retina specific member of the ATP-binding cassette transporter super-family (ABCA4) have been associated with a diverse group of human retinal diseases....Full Text Available
Random forest (RF) analysis of genetic data does not require specification of the mode of inheritance, and provides measures of variable importance that incorporate interaction effects. In this paper...Full Text Available
BackgroundRecently, the discovery of copy number variation (CNV) led researchers to think that there are more variations of genomic DNA than initially believed. Moreover, a certain...Full Text Available
Neuropilin-1 (NRP1) acts as a co-receptor for class 3 semaphorins and vascular endothelial growth factor and is an attractive angiogenesis target for cancer therapy. In addition to the transmembrane...Full Text Available
BackgroundGene regulation is a key mechanism in higher eukaryotic cellular processes. One of the major challenges in gene regulation studies is to identify regulators affecting the...Full Text Available
Stem cells of the human prostate gland have not yet been identified utilizing a structural biomarker. We have discovered a new prostatic epithelial cell phenotype-expressing cytokeratin 6a (Ck6a+...Full Text Available
A mutation in a new gene, molR, prevented the synthesis in Escherichia coli of molybdoenzymes, including the two formate dehydrogenase isoenzymes, nitrate reductase and trimethylamine-N-oxide reductase....Full Text Available
Skeletal formation is an essential and intricately regulated part of vertebrate development. Humans and mice deficient in Growth and Differentiation Factor 6 (Gdf6) have numerous...Full Text Available
Methylation of the arginine residues of histones by methyltransferases has important consequences for chromatin structure and gene regulation; however, the molecular mechanism(s) of methyltransferase...Full Text Available
Using a genetic screen we have identified two chromosomal genes, cusRS (ylcA ybcZ), from Escherichia coli K-12 that encode a two-component, signal...Full Text Available
Background and AimsSulfonylurea (SU) herbicides are used extensively in cereal–livestock farming zones as effective and cheap herbicides with useful levels of residual activity....Full Text Available
A duplication of the polypurine tract (PPT) at the center of the human immunodeficiency virus type 1 (HIV-1) genome (the cPPT) has been shown to prime a separate plus-strand initiation and to result...Full Text Available
Speech and language disorders are some of the most common referral reasons to child development centers accounting for approximately 40% of cases. Stuttering is a disorder in which involuntary...Full Text Available
The Carassius auratus complex in natural populations includes diploid triploid and polyploidy individuals. Diploid individuals belong to the species Carassius auratus...Full Text Available
Calorie restriction (CR) induces a metabolic shift towards mitochondrial respiration; however, molecular mechanisms underlying CR remain unclear. Recent studies suggest that CR-induced mitochondrial...Full Text Available
The definition of “minor” veins in leaves is arbitrary and of uncertain biological significance. Generally, the term refers to the smallest vein classes in the leaf, believed to function...Full Text Available
Telomerase, a ribonucleoprotein enzyme that maintains telomere length, is crucial for cellular immortalization and cancer progression. Telomerase activity is attributed primarily to the expression of...Full Text Available
Osteoblasts are the primary cells responsible for bone formation. They also support osteoclast formation from bone marrow precursors in response to osteotropic factors by inducing receptor activator...Full Text Available
... The basal markers CK5, alpha 6 integrin (CD49f), CD44, and p63 were strongly expressed by the majority of sphere-forming cells. ... p63 p63 PSCA ...
The Moloney murine leukemia virus (MMLV) belongs to the Retroviridae family of enveloped viruses, which is known to acquire minute amounts of host cellular proteins both on the surface...Full Text Available
Bortezomib/PS-341/Velcade, a proteasome inhibitor, is widely used to treat multiple myeloma. While several mechanisms of the cytotoxicity of the drug were proposed, the actual mechanism remains elusive....Full Text Available
Acute myocardial infarction (AMI) is a common cause of death for which effective treatments are available provided that diagnosis is rapid. The current diagnostic gold standards are circulating cardiac...Full Text Available
CTX-M extended-spectrum β-lactamases (ESBLs) are increasingly prevalent worldwide among Escherichia coli bacteria, mostly in community-acquired urinary tract infections. Finding...Full Text Available
CTX-M-14 β-lactamase was identified in a stool isolate of Shigella sonnei and in blood isolates of Escherichia coli (one isolate) and Klebsiella pneumoniae...Full Text Available
BackgroundASCL1 role in pancreatic endocrine tumourigenesis has not been established. Recently it was suggested that ASCL1 negatively controls expression of the...Full Text Available
Aiming at the non-stationary characteristics of differential pressure fluctuation signals of gas-liquid two-phase flow, and the slow convergence of learning and liability of dropping into local minima for BP neural networks, flow regime identification method based on Singular Value Decomposition (SVD) and Least Square Support Vector Machine (LS-SVM) is presented. First of all, the Empirical Mode Decomposition (EMD) method is used to decompose the differential pressure fluctuation signals of gas-liquid two-phase flow into a number of stationary Intrinsic Mode Functions (IMFs) components from which the initial feature vector matrix is formed. By applying the singular vale decomposition technique to the initial feature vector matrixes, the singular values are obtained. Finally, the singular values serve as the flow regime characteristic vector to be LS-SVM classifier and flow regimes are identified by the output of the classifier. The ...
The biological accumulation of heavy metals and cesium, strontium, and uranium in plants is discussed. The role of nutrient deficiencies and foliar treatments of manganese and iron compounds is described.
A nodulation plasmid, pRtr-514a, of molecular size 180 megadaltons (Mdal) was identified in Rhizobium trifolii strain NZP514. This plasmid was absent in both spontaneous and heat-cured Nod- derivatives...Full Text Available
BackgroundThe hard clam, Mercenaria mercenaria, has been affected by severe mortality episodes associated with the protistan parasite QPX (Quahog Parasite Unknown)...Full Text Available
OBJECTIVE:To evaluate the profile of osteoporosis treatment among patients hospitalized due to hip fractures at a tertiary-level university hospital. To compare the impact of hospitalization...Full Text Available
Epigenetic remodeling is a hallmark of cancer, with the frequent acquisition of de novo DNA methylation in CpG islands. However, the functional relevance of de novo...Full Text Available
The hyaluronic acid capsule of Streptococcus uberis has been implicated in conferring resistance to phagocytosis by bovine neutrophils. Construction of a bank of random insertion mutants...Full Text Available
A synthetic strategy for constructing ionic hydrogen-bonded materials by combining perhalometallate anions with cations able to serve as hydrogen bond donors is presented. The approach is based on identification...Full Text Available
The identification of host cell factors for virus replication holds great promise for the development of new anti-viral therapies. Recently, high-throughput screening methods have emerged as...Full Text Available
Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young non-vaccinated persons have renewed interest in this zoonotic disease. Usually causing...Full Text Available
The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available
We report on genetic identification of ‘whale meat’ purchased in sushi restaurants in Los Angeles, CA (USA) in October 2009 and in Seoul, South Korea in June and September 2009. Phylogenetic...Full Text Available
We present an algorithm to identify individual neural spikes observed on high-density multi-electrode arrays (MEAs). Our method can distinguish large numbers of distinct neural units, even when spikes...Full Text Available
Linking biological samples found at a crime scene with the actual crime event represents the most important aspect of forensic investigation, together with the identification of the sample donor. While...Full Text Available
The development of chromatin immunoprecipitation methods coupled with DNA microarray (ChIP-chip) technology has enabled genome-wide identification of cis-DNA regulatory elements to which transcription...Full Text Available
The contents of the report include: Identification, documentation and delineation of coastal migratory bird habitat; and an annotated bibliography of literature on Alaska Water Birds.
We classified microorganisms from the clinical laboratory by using information provided by the Gram stain and antibiotic sensitivity profiles obtained with the Bauer-Kirby technique. Approximately 4,000...Full Text Available
Humans are remarkably adept at identifying individuals by the sound of their voice, a behavior supported by the nervous system’s ability to integrate information from voice and speech...Full Text Available
The most important developments in gaseous detectors at LNL are reviewed. Some aspects of timing, pulse height and position resolutions of avalanche counters are reported. The experimental work on heavy-ion identification by Bragg curve spectroscopy is summarized.
Molecular genetic analysis of Borrelia burgdorferi, the cause of Lyme disease, has been hampered by the absence of any means of efficient generation, identification, and complementation...Full Text Available
Denaturing high-performance liquid chromatography (DHPLC) has been used extensively to detect genetic variation. We used this method to detect and identify Yersinia pestis KIM5 ciprofloxacin-resistant...Full Text Available
Several Bartonella species have now been implicated as human pathogens. The recovery of these fastidious organisms in the clinical microbiology laboratory remains difficult, and current...Full Text Available
Real-time PCR has the potential to streamline detection and identification of Cryptosporidium spp. in human clinical samples. In the present...Full Text Available
The identification of the protein targets for dengue virus-specific T lymphocytes may be useful for planning the development of subunit vaccines against dengue. We studied the recognition by murine...Full Text Available
BackgroundOncidium spp. produce commercially important orchid cut flowers. However, they are amenable to intergeneric and inter-specific crossing making phylogenetic...Full Text Available
Secretariat of the Basel Convention United Nations Office at Geneva ...such as public utilities, waste disposal sites, large energy dependent facilities including factories, institutions (hospitals, ...it provides immediate identification of PCB wastes, informs company officials of any special handling or disposal techniques
We previously reported the identification of a new family of plant methyltransferases (MTs), named the SABATH family, that use S-adenosyl-l-methionine (SAM) to methylate...Full Text Available
Feb 19, 2009 ... Standard Practice for Military Marking. MIL-STD-130. K. 1/15/00. Identification Marking of U.S. Military Property. MIL-STD-2073-1. D. Notice 1 ...
The authors extend the Fermilab formalism for heavy quarks to develop an {Omicron}(a{sup 2}) improved relativistic action. They discuss their construction of the action, including the identification of redundant operators and the calculation of the improvement coefficients.
The identification of MHC class II restricted peptide epitopes is an important goal in immunological research. A number of computational tools have been developed for this purpose, but there is a lack...Full Text Available
Detection and quantification of prion infectivity is a crucial step for various fundamental and applied aspects of prion research. Identification of cell lines highly sensitive to prion infection led...Full Text Available
...Amendments to Sections 8-2:704 (Use of Certain Fuel Oils Forbidden), 8-2:705 (Use of Certain Coal Forbidden...and Nitrogen Oxides. Section 801(Sulfur Content of Fuel Oils), subsection 801.1 Section 802(Sulfur...
...Department of Environmental Control to ASARCO Incorporated. (B) Amended Administrative...Department of Environmental Control to ASARCO Incorporated. (C) Second Amended...Department of Environmental Control to ASARCO Incorporated. (ii) Additional...
...analysis for all of the stacks except the ASARCO stacks. (i) Incorporation by reference...1985 (except for materials pertaining to ASARCO), and January 28, 1986 (except for meterials pertaining to ASARCO and Appendix A). (19) On...
The purpose of this report is to describe the sampling approaches, modifications made to the 100 Area and 300 Area component of the RCBRA Sampling and Analysis Plan, summarize validation efforts, and provide sample identification numbers.
This report summarises nearly 20 biosphere reports and gives a synthesis of the work performed within the SR-Site Biosphere project, i.e. the biosphere part of SR-Site. SR-Site Biosphere provides the main project with dose conversion factors (LDFs), given a unit release rate, for calculation of human doses under different release scenarios, and assesses if a potential release from the repository would have detrimental effects on the environment. The intention of this report is to give sufficient details for an overview of methods, results and major conclusions, with references to the biosphere reports where methods, data and results are presented and discussed in detail. The philosophy of the biosphere assessment was to make estimations of the radiological risk for humans and the environment as realistic as possible, based on the knowledge of present-day conditions at Forsmark and the past and expected future development of the site. This was achieved by using the best available ...
Venomous mammals are rare, and their venoms have not been characterized. We have purified and characterized the blarina toxin (BLTX), a lethal mammalian venom with a tissue kallikrein-like activity...Full Text Available
The purpose of this study was to assess the utility of the Arabic translation of the Alcohol Use Disorders Identification Test (AUDIT) among a sample of male Muslim prisoners (N = 107) in Dubai, United Arab Emirates (UAE). Confirmatory factor analysis indicated a two-factor model to be the best fit of the data. Good internal reliability (a =.91) and predictive validity were also observed. While the limitations of the study are observed, these promising results suggest that the Arabic version of the AUDIT is a reliable and sound measure of alcohol use disorders among prisoners in the UAE.
The basic approach to radioactive labeling techniques in hemoglobin identification consists of mixing 14C labeled normal carrier globin with 3H labeled unknown globin and carrying out the subsequent separations and purifications looking at the distribution of 3H and 14C radioactivity. This technique was devised to ascertain the amino acid substitution in Hb Indianapolis and was instrumental in solving the structure of Hb Vicksburg. It was also useful in determining the purity of gamma-chains from cultures of human and baboon erythroid progenitors. Another use of this technique would be in identifying aberrant peaks of radioactivity in chain separation chromatograms, such as ''pre-peaks''.
This report describes an improved method of remotely identifying irradiated nuclear fuel assemblies. The method uses existing in-cell TV cameras to input an image of the notch-coded top of the fuel assemblies into a computer vision system, which then produces the identifying number for that assembly. This system replaces systems that use either a mechanical mechanism to feel the notches or use human operators to locate notches visually. The system was developed for identifying fuel assemblies from the Fast Flux Test Facility (FFTF) and the Clinch River Breeder Reactor, but could be used for other reactor assembly identification, as appropriate.
A multiple sampling dE/dx counter using a multiwire proportional chamber equipped with catbode pads was constructed for the multiple detection of dE/dx values along a particle trajectory. For low-energy particles this counter was proved to be useful as a Bragg-curve detector. At relativistic energies around E=14.6 GeV/nucleon good particle identification was obtained by cathode pad signals as well as anode signals for the range of projectile fragments from Z=1 (minimum ionization) up to a beam charge of Z=14. (orig.).
Twenty-six unclassified Campylobacter-like strains previously isolated from 15 chicken carcasses and caecal contents, together with two more strains isolated from chicken faeces on a different occasion, were identified as Helicobacter pullorum using various phenotypic identification methods. API Campy identification kits and a 16-test identification scheme developed for campylobacters failed to identify these bacteria, or identified them as Campylobacter spp. Eighteen strains (including the two isolated on a different occasion) were chosen for examination using a more comprehensive probabilistic identification scheme. Using this method, 14 of the 18 strains were identified as H. pullorum with ID scores > 95%; two strains were also identified as H. pullorum with lower ID scores. Of the remaining two strains, one was not identified with this scheme and the other was misidentified to the H, acinonyx ...
Evidence for the presence of undecaprenol in the unsaponifiable lipid of Lactobacillus plantarum (N.C.I.B. 6376) is presented. Characterization of the compound was based mainly on...Full Text Available
Robert A. Martock. Cleveland State University, Cleveland, Ohio. Synthesis and Structural Characterization of a. Novel Indium Mercapto Derivative. [Clln(SCH. 2 ...
Recent molecular characterizations of Cryptosporidium parasites make it possible to differentiate the human-pathogenic Cryptosporidium parasites from those that do...Full Text Available
This paper describes attempts to isolate and characterize glycosaminoglycan (GAG)-binding molecules on the surface of lymphocytes and lymphoma cell lines and relate their expression to splenic and lymph...Full Text Available
BackgroundA mycovirus previously identified in brown discolored fruiting bodies of the cultivated mushroom Flammulina velutipes was characterized. We tentatively...Full Text Available
The objectives of this project are to detect and characterize fractures in a naturally fractured tight gas reservoir, using surface seismic methods, borehole imaging logs, and in-situ stress field data. Further, the project aims to evaluate the various seismic methods as to their effectiveness in characterizing the fractures, and to formulate the optimum employment of the seismic methods as regards fracture characterization.
Gastric stromal tumors are an ill-defined group of lesions arising from muscle wall cells and characterized by extremely variable biological patterns. Thanks to modern immunohistochemical and ultrastructural techniques, four main classes of these lesions have been identified, namely: (1) tumors with differentiation toward smooth muscle cells; (2) tumors with differentiation toward neural elements; (3) tumors with differentiation toward neural elements; (3) tumors with dual differentiation toward either cell type. It was investigated the yield of CT in diagnosing and characterizing gastric stromal tumors. It was retrospectively reviewed the CT findings of 38 patients (15 men and 23 women; mean age 51 years) with pathologically proven gastric stromal tumors, namely 31 of myoid origin, 4 of neural origin, 2 with both muscle and neural differentiation, 1 lacking differentiation with either cell type. The myoid tumors involved gastric fundus in 9/13 ...
This thesis presents measurements of inelastic photoproduction and electroproduction of J/{psi} mesons in ep scattering at HERA. The data was collected by the H1 detector during the HERA II running and corresponds to an integrated luminosity of L {approx} 166 pb{sup -1} in the photoproduction analysis and L {approx} 315 pb{sup -1} in the electroproduction analysis. In both analyses the elasticity of the J/{psi} meson is restricted to a medium range of 0.3 {<=} z {<=} 0.9. The kinematic range of the photoproduction analysis is defined by Q{sup 2} {approx} 0 GeV{sup 2}, 60 {<=}W{sub {gamma}}{sub p}{<=} 240 GeV and P{sub {tau}}{sub ,{psi}}{>=} 1 GeV{sup 2}, whereas the electroproduction analysis is restricted to 3.6 {<=} Q{sup 2} {<=} 100 GeV{sup 2}, 50 {<=}W{sub {gamma}}{sub p}{<=} 225 GeV, and P{sup *}{sub {tau}}{sub ,} {sub {psi}} {>=} 1 GeV. Here P{sup *}{sub {tau}}{sub ,} {sub {psi}} denotes ...
Skin sensitization is the most commonly reported occupational illness, causing much suffering to a wide range of people. Identification and labeling of environmental allergens is urgently required to protect people from skin sensitization. The guinea pig maximization test (GPMT) and murine local lymph node assay (LLNA) are the two most important in vivo models for identification of skin sensitizers. In order to reduce the number of animal tests, quantitative structure-activity relationships (QSARs) are strongly encouraged in the assessment of skin sensitization of chemicals. This paper has investigated the skin sensitization potential of 162 compounds with LLNA results and 92 compounds with GPMT results using a support vector machine. A particle swarm optimization algorithm was implemented for feature selection from a large number of molecular descriptors calculated by Dragon. For the LLNA data set, the classification accuracies are 95.37% and ...
A heavy ion gas detector system consisting of a Bragg-curve spectroscopy ionization chamber for particle identification and a multiwire proportional chamber as position sensitive fast trigger device is described. The Bragg IC has been tested with several beams up to Z=36 to investigate some aspects of the BCS method. Results are reported on energy resolution and linearity, Z resolving power and mass sensitivity. The energy resolution is well below 1%. The Bragg-peak amplitude is fairly independent of the energy in a wide energy range and single elements are identified up to Z=38 with a resolving power Z/..delta..Zproportional50-80. Isotope identification by range measurement is limited by the straggling in the ionization process and the mass resolving power is M/..delta..Mproportional20-26 for S and Si isotopes. The MWPC allows subnanosecond time resolution and position identification along the in-plane coordinate within ...
A heavy ion gas detector system consisting of a Bragg-curve spectroscopy ionization chamber for particle identification and a multiwire proportional chamber as position sensitive fast trigger device is described. The Bragg IC has been tested with several beams up to Z=36 to investigate some aspects of the BCS method. Results are reported on energy resolution and linearity, Z resolving power and mass sensitivity. The energy resolution is well below 1%. The Bragg-peak amplitude is fairly independent of the energy in a wide energy range and single elements are identified up to Z=38 with a resolving power Z/#DELTA#Zproportional50-80. Isotope identification by range measurement is limited by the straggling in the ionization process and the mass resolving power is M/#DELTA#Mproportional20-26 for S and Si isotopes. The MWPC allows subnanosecond time resolution and position identification along the in-plane coordinate within +-0.5 ...
To increase further the accuracy of flow regime and considering the non-stationary characteristics of differential pressure fluctuation signals of gas-liquid two-phase flow, the flow regime identification method based on recurrence quantification analysis (RQA) and multi-sensor data fusion techniques is put forward. First of all, the recurrence quantification analysis method is used to extract the nonlinear feature parameters of the differential pressure fluctuation signals of gas-liquid two-phase flow, and data fusion of feature layer is conducted by QRA feature parameters of differential pressure signals of three pressure measure intervals, and composes the fusion feature vectors. The fused characteristic vector are input into the support vector machine for identify flow regime. The identification results for four typical flow regimes of air-water two-phase flow in horizontal pipe has shown that the reliability of the ...
Lanthanum halide (LaBr_3:Ce) scintillators offer significantly better resolution (< 3% at 662 keV) relative to NaI(Tl) and have recently become commercially available in sizes large enough for the handheld, Radio-Isotope Identification Device (RIID) market. Drawbacks to lanthanum halide detectors, however, include internal radioactivity contributing to spectral counts, and a low-energy response which can cause detector resolution to be worse than that of NaI(Tl) below 100 keV. To study the potential of this new material for RIIDs we performed a series of measurements comparing a 1.5 x 1.5-inch LaBr_3:Ce detector with an Exploranium GR-135 RIID, which contains a 1.5 x 2.2-inch NaI(Tl) detector. Measurements were taken for short timeframes, as typifies RIID usage. Measurements included examples of naturally occurring radioactive material (NORM), typically found in cargo, and special nuclear materials. Some measurements were non-contact, involving short distances ...
With steam generator check testing, the numerous types of defect not only have to be detected reliably but also to be identified correctly and classified according to depth. A priori, no signals are provided by the physical eddy-current mechanism, i.e. the disturbance of an excited eddy-current field by a defect, which will allow unambiguous identification and classification of the defects. The task, therefore, consists in designing the eddy-current method in terms of measurement technology in such a way as to obtain useful detection, identification and classification by a translation of the signals as simple and as save as possible. Internal through-flow wils and internal rotating probes were examined for their suitability to fulfill this three-pronged task with steam generator inspection.
With steam generator check testing, the numerous types of defect not only have to be detected reliably but also to be identified correctly and classified according to depth. A priori, no signals are provided by the physical eddy-current mechanism, i.e. the disturbance of an excited eddy-current field by a defect, which will allow unambiguous identification and classification of the defects. The task, therefore, consists in designing the eddy-current method in terms of measurement technology in such a way as to obtain useful detection, identification and classification by a translation of the signals as simple and as save as possible. Internal through-flow wils and internal rotating probes were examined for their suitability to fulfill this three-pronged task with steam generator inspection. (orig./RW).
Physicians are exercising their responsibility as healers in their efforts to prevent nuclear war. Death for Hiroshima survivors was experienced in four stages: the immediate impact of destruction, the acute impact of radiation, delayed radiation effects, and later identification as an atomic bomb survivor. Each phase had its physical and psychological impacts and negates Hiroshima as a model for rational behavior despite those who claim survival is possible for those who are prepared. The psychic effects of modern nuclear, chemical, and germ warfare need to be challenged with a symbolization of life and immortality. Studies of psychological reactions to the terror children felt during practice air-raid drills indicate that the fears can be surpressed and re-emerge in adult life as a linking of death with collective annihilation. Other themes which emerge are feelings of impermanence, craziness, identification with the bomb, and a double ...
Polyethylene pipes and connections are being widely used in treated water distribution services. Migration of low molecular weight compounds from the polyethylene into the water can change its final quality. This paper is about the concentrations and identification of the migration compounds found in treated water after staying in contact with low and high-density polyethylene. Identification and quantification were carried out using CLSA (Closed Loop Stripping Analysis) extraction technique and gas chromatography coupled to mass spectrometry (HRGC/HRMS). (Author) 12 refs.
This report describes all time and frequency analysis parameters measured with the new Nuclear Weapons Identification System (NWIS) processor with three input channels: (1) the {sup 252}Cf source ionization chamber; (2) a detection channel; and (3) a second detection channel for active measurements. An intuitive and physical description of the various functions is given as well as a brief mathematical description and a brief description of how the data are acquired. If the full five channel capability is used, the number of functions increases in number but not in type. The parameters provided by this new NWIS processor can be divided into two general classes: time analysis signatures including multiplicities and frequency analysis signatures. Data from measurements with an 18.75 kg highly enriched uranium (93.2 wt%, {sup 235}U) metal casting for storage are presented to illustrate the various time and frequency analysis parameters.
This report describes all time and frequency analysis parameters measured with the new Nuclear Weapons Identification System (NWIS) processor with three input channels: (1) the 252Cf source ionization chamber (2) a detection channel; and (3) a second detection channel for active measurements. An intuitive and physical description of the various functions is given as well as a brief mathematical description and a brief description of how the data are acquired. If the fill five channel capability is used, the number of functions increases in number but not in type. The parameters provided by this new NWIS processor can be divided into two general classes: time analysis signatures including multiplicities and frequency analysis signatures. Data from measurements with an 18.75 kg highly enriched uranium (93.2 wt 0/0, 235U) metai casting for storage are presented to illustrate the various time and frequency analysis parameters.
A time-of-flight (TOF) spectrometer has been constructed at the JAERI 20 MV tandem accelerator facility. A position-sensitive start detector, which consists of a thin carbon foil, microchannel plates and a resistive plate, was developed for the TOF measurements through the spectrometer. The time and position resolutions obtained were 120 ps and 0.3 mm for ..cap alpha.. particles from /sup 241/Am, respectively. A two-dimensional position-sensitive detector was also developed to measure the solid angle of the spectrometer and the maximum solid angle obtained was 9.5 msr. As a particle detector a Bragg curve ionization chamber was developed. From the Bragg curves of heavy ions in the detector, energies, ranges and Bragg curve peaks were measured and used for particle identification. The resolving power Z/..delta..Z of the atomic number was about 50.
The identification of the unknown parameters of the Duffing's mechanical system, based on an algebraic approach, is presented. This approach is fast, accurate, and simple to numerically implement. Also, the method, combined with a suitable invariant filter, can became robust against high frequency output measurement noises. Our method uses the availability of one measurable output and produces an exact formula for the unknown parameters, which may be realized in terms of iterated convolutions. First, we show that the Duffing's system parameters are linearly identifiable with respect to the position variable, then we obtain a linear system where the unknowns are the unavailable parameters. Suitable algebraic operations on the output differential equations makes the identification schema independent of the unavailable initial conditions of the underlying nonlinear dynamical system.
A novel non-invasive approach to the on-line identification of BWR two-phase flow regimes is investigated. The proposed approach receives neutron radiography images of coolant flow recordings as its input and performs feature extraction on each image via simple and directly computable statistical operators. The extracted features are subsequently used as inputs to an ensemble of self-organizing maps whose outputs demonstrate swift and accurate classification of each image into its corresponding flow regime. The novelty of the approach lies in the use of the self-organizing map which generates the different classes by itself, according to feature similarity of the corresponding images; this contrasts traditional artificial neural networks where the user has to define both the number of distinct classes as well as to supply separate training vectors for each class.
Speech perception integrates auditory and visual information. This is evidenced by the McGurk illusion where seeing the talking face influences the auditory phonetic percept and by the audiovisual detection advantage where seeing the talking face influences the detectability of the acoustic speech signal. Here, we show that identification of phonetic content and detection can be dissociated as speech-specific and non-specific audiovisual integration effects. To this end, we employed synthetically modified stimuli, sine wave speech (SWS), which is an impoverished speech signal that only observers informed of its speech-like nature recognize as speech. While the McGurk illusion only occurred for informed observers, the audiovisual detection advantage occurred for na?ve observers as well. Thi...
There is a need for earlier and more accurate cancer diagnostics as well as new targets for cancer immunotherapy. To this end, it is important to identify sets of tumour antigens specific for different cancer forms. Several methods that identify potential tumour antigens in an arrayed and high-throughput format have been developed during the last years of SEREX (serological identification of antigens by recombinant expression cloning) related research. Such techniques may hold the potential to describe the complete immunogenic part of the cancer proteome, also called the cancer immunoproteome.We have developed a powerful platform for automated serological high-throughput filter screening of tumour cDNA libraries. The screening format of this method is 18,000 single cDNAs clones, which is s...
The Lesch-Nyhan (LN) syndrome is a severe X chromosome-linked disease that results from a deficiency of the purine salvage enzyme hypoxanthine phosphoribosyltransferase (HPRT). The mutations leading to the disease are heterogeneous and frequently arise as de novo events. The authors have identified nucleotide alterations in 15 independently arising HPRT-deficiency cases by direct DNA sequencing of in vitro amplified HPRT cDNA. They also demonstrate that the direct DNA sequence analysis can be automated, further simplifying the detection of new mutations at this locus. The mutations include DNA base substitutions, small DNA deletions, a single DNA base insertion, and errors in RNA splicing. The application of these procedures allows DNA diagnosis and carrier identification by the direct detection of the mutant alleles within individual families affected by LN.
In vibration control field, magneto-rheological (MR) fluid dampers are semi-active control devices that have recently begun to receive more attention. This paper presents a black-box model (BBM) for identification of a MR fluid damper and its application to vibrating control systems using that damper with self-sensing behavior. A model named ''black-box'' is a simple direct modeling method which is designed for a typical MR fluid damper using the self-tuning fuzzy technique. The characteristics of the researched damper are directly estimated through a fuzzy mapping system. In order to improve the accuracy of the proposed model, the back propagation algorithm and gradient descent method were used to train the fuzzy parameters to minimize the model error function. Consequently, the BBM with ...
The problem of electrical parameters identification in complex systems, and in particular in electric railway traction systems, is considered. Parameters are determined by an indirect approach: only the terminal variables (voltages and currents and, impedance and admittance, which can be readily calculated) are measured and the per-unit-length electrical parameters are determined using a multiconductor transmission line model of the track section under test. It will be shown that some parameters cannot be measured directly, that they are not constant with frequency and that they may depend on other external conditions. An indirect method for parameters identification is proposed through an adaptive algorithm (AA), so that the calculated terminal variables match the measured ones. The AA is...
An improved singular value decomposition method of gear fault identification based on Hilbert-Huang transform was proposed to overcome the problem of reconstructing a feature matrix of singular value decomposition. The method includes three steps. First, the instantaneous frequency and amplitude matrices were acquired by Hilbert-Huang transform from faulted gear signals. Second, after the matrices were decomposed by singular value decomposition, the defined distances of singular value vectors and the optimal threshold of the distance for classification were calculated. Third, the fault characteristics of a gearbox were identified and classified by the threshold of the distances. The result demonstrates that the proposed method effectively identifies the gear fault and can realize an automa...
Experience with the identification and tuning of exciter constants for a generating unit as the Second Nuclear Power Plant of Taiwan Power Company is reported. Field test is first performed on the excitation system with the generator open-circuited. Since the field test results differ from the computer simulation results using manufacturer`s constants, the authors first modify the manufacturer`s constants based on their previous experience to reach a preliminary set of parameters for the excitation system. Then a hybrid nonlinear simulation-sensitivity matrix method is developed to further refine the excitation system parameters. The exciter constants are tuned in order to give better dynamic response before a power system stabilizer is applied to the generator. Field tests are then performed in order to compare the dynamic response of the generator without and with power system stabilizer.
Experience with the identification and tuning of exciter constants for a generating unit as the Second Nuclear Power Plant of Taiwan Power Company is reported. Field test is first performed on the excitation system with the generator open-circuited. Since the field test results differ from the computer simulation results using manufacturer's constants, the authors first modify the manufacturer's constants based on their previous experience to reach a preliminary set of parameters for the excitation system. Then a hybrid nonlinear simulation-sensitivity matrix method is developed to further refine the excitation system parameters. The exciter constants are tuned in order to give better dynamic response before a power system stabilizer is applied to the generator. Field tests are then performed in order to compare the dynamic response of the generator without and with power system stabilizer.
The study reports the identification of different organic acids that are formed during the pyrohydrolysis of mixed carbide of uranium and plutonium using ion chromatography (IC). The identification of organic acids present in the pyrohydrolysis distillate is required to carry out interference free analysis of Cl and F. The study describes three stage isocratic separations with NaOH eluents having concentrations 2 mM, 10 mM and 50 mM respectively in order to separate and identify both aliphatic and aromatic acids. The present investigation identified formic, acetic, propionic, butyric, tartaric and oxalic acids in the distillate, however, aromatic acids could not be identified. (author)
A simple electromagnetic transport system was constructed to identify very rare positrons produced in a powerful laser beam interaction with a target. Testing experiments were carried out with CO[sub 2]-laser (10[sup 12] W/cm[sup 2]) beam pulses ([tau] = 50 ns, f = 0.01 Hz) focused on the copper target, as well as with a 96 MeV alpha-particle beam irradiated carbon target. The results showed that the developed system could be effectively used for positron identification and evaluation of their energy by means of a time-of-flight method. The computerized system to deal with this problem, together with others related to the power laser beam interaction with targets, has been constructed. (orig.).
The PVSCAN is an instrument designed to characterize silicon solar cell materials and devices. It performs a host of measurements that yield spatial maps of dislocation density, grain distribution, reflectance, and photoresponses from near-junction and the bulk of a solar cell.
Subcellular-fractionation techniques were used to characterize the endocytic pathway followed by ricin in rat liver in vivo and tentatively identify the site(s) at which the ricin interchain disulphide...Full Text Available
This work describes the synthesis and characterization of novel thermoresponsive highly-branched polyamidoamine-polyethylene glycol-poly (D, L-lactide) (PAMAM-PEG-PDLLA) core-shell nanoparticles....Full Text Available
The characterization of the single-chain protein in Chinese-cobra (Naja naja atra) blood serum, which yields strong specific protection against the venom of the same snake, is reported. The protein,...Full Text Available
BackgroundHepatitis A virus (HAV) strains detected in environmental and clinical samples were analysed to characterize the genotypes of HAV circulating in Greece. Fifty (50) sewage...Full Text Available
This paper describes a system for fast mass spectrometric characterization of high-temperature outgassing measurements and measuring the total quantity of gas evolved for boron nitride. 2 references, 1 figure, 2 tables.
We describe here seven cases (from five kindreds) of Anderson's disease, which is characterized by diarrhea, steatorrhea, hypobetalipoproteinemia with low levels of cholesterol, triglycerides, and phospholipids,...Full Text Available
The functional gene and three intronless pseudogenes for human triosephosphate isomerase were isolated from a recombinant DNA library and characterized in detail. The functional gene spans 3.5 kilobase...Full Text Available
We have cloned and characterized the entire DNA polymerase gene and flanking regions from Kaposi's sarcoma-associated herpesvirus (KSHV) and two closely related macaque homologs of KSHV, retroperitoneal...Full Text Available
Bi-U mixed oxides were synthesized by two methods and characterized by X-ray diffraction and X-ray photoelectron spectroscopy. The samples were tested for the catalytic oxidation of carbon monoxide by oxygen. A stepwise redox mechanism consistent with the kinetic results is proposed. (orig.).
The abstracts of all the presentations (1 plenary session, 2 keynotes, 52 oral communications, 496 posters) of the thematic session 1: 'catalyst preparation and characterization' are gathered in the CD-Rom of the conference. The main application described concerns the petroleum industry. (O.M.)
Context: Mild primary hyperparathyroidism (PHPT) is characterized by asymptomatic hypercalcemia, most commonly in the absence of classical signs and symptoms. Hence, there is need to characterize...Full Text Available
... The SMSP makes predictions based on historical precipitation data, precipitation ... are characterized by relatively large areas of strategic interest. ...
In accordance with the requirements of Section 113 (b) (3) of the Nuclear Waste Policy Act of 1982, as amended (NWPA), the US Department of Energy (DOE) has prepared this report on the progress of site characterization activities at Yucca Mountain, Nevada, for the period October 1, 1990, through March 31, 1991. This report is the fourth in a series of reports that are issued at intervals of approximately six months during site characterization. The report covers a number of initiatives to improve the effectiveness of the site characterization program, and covers continued efforts related to preparatory activities, Study Plans, and performance assessment.
Total dose irradiation effects on a VDMOS developed at Institute of Microelectronics, CAS were investigated, particularly the electric parameter changes under different bias conditions. It was found that the breakdown voltage degradation by the irradiation depended mainly on the drain bias, whereas the threshold voltage degradation depended mainly on the gate bias. Thus, an innovative and effective method to domestic VDMOS total dose ionization characterization is that threshold voltage radiation hardening characterization should be tested on gate bias condition, and the breakdown voltage radiation hardening characterization, be tested on the drain bias. (authors)
The objective of this animation is to develop a QTL mapping population for locating and characterizing the genes responsible for resistance to tan spot disease of wheat.
The paper provides a brief description of the fuel characterization for Fast Breeder Test Reactor (FBTR) and Prototype Fast Breeder Reactor (PFBR). The development and characterization of mechanical properties of Alloy D9 clad and wrapper tubes are discussed. The problems associated with fusion welding of Alloy D9 are outlined. Non-destructive characterization of cladding tubes by optimum encircling eddy current probes, on-line and off-line neural network methods is presented. Both the on-line and off-line neural network methods could readily detect and size defects specified by the designers
... Abstract : The beater additive process for manufacturing combustible cartridge cases is superior to the solvent resin, post-impregnation process. ...
This report provides analytical results for groundwater collected during four characterization-sampling rounds conducted at well R-22 from March 2001 through March 2002. Characterization well R-22 was sampled from March 6 through 13, 2001; June 19 through 26, 2001; November 30 through December 10, 2001; and February 27 through March 7, 2002. The goal of the characterization efforts was to assess the hydrochemistry and to determine whether or not contaminants are present in the regional aquifer in the vicinity of the well. A geochemical evaluation of the analytical results for the well is also presented in this report.
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and dioxin-like compounds are widely encountered toxic substances suspected of interfering with the endocrine systems of humans and wildlife,...Full Text Available
This article describes the preparation of 5-nitroisatin and of 5-chloroisatin from isonitrosoacetanilide in a single step, using readily available and inexpensive reagents. These reactions require around 90 minutes and may be carried out as an undergraduate experiment, providing an opportunity to discuss the electrophilic aromatic substitution mechanism, as well as spectroscopic techniques for product identification. (author)
Abstract in english This report deals with the identification of samples of nematodes recovered from Tropidurus nanuzae Rodrigues, 1981, with the description of a new species, and is a part of a major study on helminth parasites of reptiles in Brazil, taking into account previous data on this subject. The main approach is that referring to the first occurrence of subulurid nematodes in a reptilian host, since they have been assigned previously to birds and mammals.
This paper dealt with the identification of possible damaging mechanism of the collector of the WWER 440 steam generator, cracking of primary collectors, corrosion damage of the protective coat of the primary collector circumferential weld, cracking of breathing space in the region of blinding effect by corrosion and strain, leaking of disassembling joint of the primary collector lid and with the integrity of heat exchanging tubes.
Giving many examples, the contribution shows how pump operators may influence the life, efficiency and overall cost of their pumps. Further, it is shown that both the detection of unfavourable or non-optimal operating conditions and the identification of causes necessitate extensive knowledge and experience. (orig.)
The feasibility was studied of the application of radionuclide X-ray fluorescence analysis to the identification and determination of chemical elements in the air. A description of the method is presented, the main stages of the analysis are discussed (sample preparation and standards, selection of radioactive radiation sources, geometry of measurement and evaluation of results). The method is illustrated on the determination of elements Fe, Cu, Zn, Br, and Pb in air samples taken in the city of Prague. (author) 2 tabs., 2 figs., 14 refs.
We compute the potential for localized closed string tachyons in bosonic string theory on the orbifold C/Z{sub 4} using level-truncated closed string field theory. The critical points of the potential exhibit features which agree with their conjectured identification as lower-order orbifolds. However this case also raises some questions regarding the quantitative predictions associated with these conjectures. (author)
A 13.1-kb DNA fragment carrying Pseudomonas denitrificans cob genes has been sequenced. The nucleotide sequence and genetic analysis revealed that this fragment contained five different cob genes named...Full Text Available
BackgroundPlasmid encoded blaCTX-M enzymes represent an important sub-group of class A β-lactamases causing the ESBL phenotype which is increasingly...Full Text Available
An (Awassi × Merino) × Merino backcross family of 172 ewes was used to map quantitative trait loci (QTL) for different milk production traits on a framework map of 200 loci across all...Full Text Available
The long-range correlation properties in the hourly time variability of geochemical signals measured in a 70 m depth well at Triponzo (Umbria region), are investigated by the detrended fluctuation analysis (DFA). DFA is a data processing method that allows for the detection of scaling behaviors in observational time series even in the presence of non-stationarities. The procedure adopted has allowed for the unambiguous identification of possible correlations among the recorded signals and local earthquakes.
The bibliography contains citations concerning Federal and state laws and management programs for the protection and use of inland wetlands. Utilization of wetlands to control highway runoff and community wastewater is discussed. Wetlands protection programs, restoration projects, resource planning, and wetlands identification methods are cited. References to coastal and salt water wetlands are not included in this bibliography. (Contains 250 citations and includes a subject term index and title list.)
...Identification - ETI Food & Biobased Research (WUR) Freudenthal Institute - FIsme (UU) Holst Centre IKM Engineering Ltd Information Retrieval and Information Systems (KUN) Information Systems - INS Information Technology Group (WUR) Institute for Computing and Information Sciences - ICIS (KUN) Institute of Health Policy and Management (EUR) ...
The etching method developed made it possible to observe under the microscope the finest components of the anatomical structure of coal-forming plants. The dependence of the effectiveness of etching of tissues on the concentrations of geopolymers (protocellulose and protolignin) in them was found. The study of tissues of this kind by the methods of local analysis (for example, X-ray microanalysis) allowed us to obtain the characteristics of the above geopolymers and to use them for the identification of the primary biochemical composition of fossil organic matter.
Hydrology and hydrogeochemical are auxiliary techniques to valid conceptual hydrogeology an recharge models. Stable isotopes from water trace sources and path flow and Tritium indicates age. This paper is about the use of D 18, D2H y 3H to study the aquifer system on Bajo Cauca antioqueno.
Objectives1) To establish a protocol for transfection of immortalised type I cells with SiRNA and its effect on cell viability; 2) To optimise silencing of genes involved in endocystosis using SiRNA and confirm successful transfection with western blotting; 3) To investigate the effect of gene silencing on uptake of flourescently-labelled latex nanoparticles.DescriptionTo investigate the mechanisms of particle uptake.
PCD (programmed cell death) in plants presents important morphological and biochemical differences compared with apoptosis in animal cells. This raises the question of whether PCD arose independently...Full Text Available
The sequence and cytological location of five Anopheles gambiae glutathione S-transferase (GST) genes are described. Three of these genes, aggst1-8, aggst1-9 and aggst1-10, belong to the insect class...Full Text Available
We have identified another Drosophila GTP-binding protein (G protein) alpha subunit, dGq alpha-3. Transcripts encoding dGq alpha-3 are derived from alternative splicing of the dGq alpha locus previously...Full Text Available
BackgroundThe Ras and Notch signaling pathways are frequently activated during development to control many diverse cellular processes and are often dysregulated during tumorigenesis....Full Text Available
Chemical contamination can be one of the more common problems encountered when performing trace-level analysis regardless of the analytical technique. Minimizing or eliminating background interferences...Full Text Available
Elements Ti, Mn, Fe, Ni, Cu, Zn, Pb, Br, Rb and Sr were determined by the method of radionuclide X-ray fluorescence analysis with semiconductor detection in samples of Taraxacum officinale from various localities of Bratislava. The dependence of their content on the source and the degree of the air pollution was found out.
Elements Ti, Mn, Fe, Ni, Cu, Zn, Pb, Br, Rb and Sr were determined by the method of radionuclide X-ray fluorescence analysis with semiconductor detection in samples of Taraxacum officinale from various localities of Bratislava. The dependence of their content on the source and the degree of the air pollution was found out. (author).
The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Document (S/RID) is contained in multiple volumes. This document (Volume 2) presents the standards and requirements for the following sections: Quality Assurance, Training and Qualification, Emergency Planning and Preparedness, and Construction.
We have used intramolecular cross-linking, MS, and sequence threading to rapidly identify the fold of a model protein, bovine basic fibroblast growth factor (FGF)-2. Its tertiary structure was probed...Full Text Available
This document, the Standards/Requirements Identification Document (S/RID) Phase 2 Assessment Report for the subject facility, represents the results of a Performance Assessment to determine whether procedures containing S/RID requirements are fully implemented by field personnel in the field. It contains a summary report and three attachments; an assessment schedule, performance objectives, and assessments for selected functional areas.
Cutaneous T-cell lymphoma is typically a clonal neoplasm of epidermotropic CD4+ T-lymphocytes that includes the entity mycosis fungoides (MF). After identification of patients with recurrent MF treated...Full Text Available
Nondestructive inspection of carbon fibre-reinforced plastics (CRFP) using eddy current methods is based not only on the conductivity of the fibres. High frequencies (up to 10 MHz) give access to capacitive effects reflecting properties of the matrix. The paper presents a method using rotating eddy current probes to measure the anisotropic electrical properties. Potential applications of this method are the structural identification of laminates and the estimating of its degradation. (orig.)
The obtained results in presently study demonstrate that the feasibility of the detection of the sentry ganglion in cervix uterine cancer using a boarding by laparoscopic via, being necessary the use of twice labelled as much with patent blue and radioisotope (colloid of labelled rhenium with "9"9"mTc, total dose of 3 MCi) to achieve the identification of the ganglion. (Author)
The intention of the research carried out was to develop photovoltaic driven solar heating systems applied for drying of medicinal plants in remote areas. Identification of hybrid photovoltaic - photothermal systems was done and discussion of technical features and applicability of such systems in agriculture is presented. Detail technical specification of PV powered medicinal plants solar dryer and cost effectiveness parameters are given. Operational and economic results obtained during testing of the dryer are promising. (orig.) 4 refs.
Preparation of the clinician to work in multicultural contexts involves the identification of a range of skills, knowledge and values. The field of narrative medicine as well as an increased understanding of the dynamics of interpreting are areas which can add considerably to clinical effectiveness. The paper outlines some cornerstones of narrative medicine and their potential application to the field of speech-language pathology and audiology. PMID:12037426
DNA from 48 hr germinated rice embryos was cut with restriction endonuclease Bam H1 and cloned to the Bam H1 site on plasmid pBR 322. The clones containing recombinant DNA were selected by their sensitivity to tetracycline and resistance to ampicillin. Using /sup 32/P-labelled rice embryos tRNA as a probe two clones were identified to contain tRNA genes by colony hybridization.
The operation principle, construction and characteristics of the Bragg curve spectroscopy detector (BCS detector) are described. The electric field of the BCS detector is parallel to the particle trajectories. The detector was tested by 8.78 MeV and 6.02 MeV #alpha# particles from a ThC-ThC's source. The energy resolutions are 1.5% and 2.6% respectively for two groups of #alpha# particles, and the charge resolution is 2.7%. Further test experiments with heavy ions will be arranged.
In this paper a phenomenological analysis of the sintering kinetics of alumina powder compacts with different proportions of small and large particles has been made. A phenomenological approach enables definition of functional connections between parameters characteristic of a certain material and the sintering time. A phenomenological equation is defined, which can be used to describe the densification process of alumina during isothermal sintering. Its parameters enable identification of the dominant diffusion mechanism. (orig.)
A dual-rate self-tuning control technique, in which the system identification and control calculation are performed separately, is proposed in this paper. This greatly increases the control rate. A self-tuning power system stabilizer (DSPSS) making use of this technique is developed and implemented using multi-micro-computers. Simulation and experimental results with DSPSS show that the increase in the control rate can considerably improve the system performance.
Described herein is an optical probe (120) for use in characterizing surface defects in wafers, such as semiconductor wafers. The optical probe (120) detects laser light reflected from the surface (124) of the wafer (106) within various ranges of angles. Characteristics of defects in the surface (124) of the wafer (106) are determined based on the amount of reflected laser light detected in each of the ranges of angles. Additionally, a wafer characterization system (100) is described that includes the described optical probe (120).
This study reports on the physical-chemical behaviour of swelling di-octahedral clays (smectites) and their interaction with aqueous solutions and bacteria (Shewanella putrefaciens). Experimental results are presented for compacted clays, hydrated under confined volume conditions, using a new type of reaction-cell (the 'wet-cell' of Warr and Hoffman, 2004) that was designed for in situ X-ray diffraction (XRD) measurement. For comparison, dispersed clay systems were studied using standard batch solutions subjected to varying degrees of agitation. The combination of time-dependent in situ XRD measurements with gravimetric measurements and calculated diffraction patterns using the CALCMIX software (Plancon and Drits, 1999) allowed to successful quantification of the dynamics of water uptake and storage. This analytical procedure combined with published water vapour adsorption data enabled determination of the abundance of structured water layers, developed in the ...
Acca sellowiana has commercial potential because of the quality and the unique flavor of its fruit. Conservation of natural populations and management of breeding programmes would benefit from the availability of molecular markers that could be used to characterize levels and distribution of genetic variability. Thus, 13 microsatellite markers were developed from an enriched genomic library of A. sellowiana. They were characterized using 40 samples. The expected and observed heterozygosities ranged from 0.513 to 0.913 and from 0.200 to 0.889, respectively. These are the first microsatellite loci characterized from A. sellowiana that will contribute to improve researches on the genetic conservation, characterization and breeding. PMID:21586063
The Measurements and Characterization Branch actively supports the advancement of DOE/NREL goals for the development and implementation of the solar photovoltaic (PV) technology. The primary focus of the laboratories is to provide state-of-the-art analytical capabilities for materials and device characterization and fabrication. The branch houses a comprehensive facility that Is capable of providing information on the full range of PV components. A major objective of the branch is to aggressively pursue collaborative research with other government laboratories, universities, and industrial firms for the advancement of Pv technologies. Members of the branch disseminate research findings to the technical community in publications and presentations. The Measurements and Characterization Branch encompasses seven coordinated research groups, providing integrated research and development that covers all aspects of photovoltaic ...
SummaryIntended Outputs: Identification and evaluation, using participatory approaches, of demand management options:*Technical*Allocative and market based*Impact on target beneficiariesSupporting measures required when introducing water demand management options above:*Extension services & training*Water licences/rights*Institutional changes*Legal measures and regulation*Education*Support in diversifying to less water demanding activities*S [continued...]ObjectivesIdentification of the most appropriate demand management strategies for ground water abstraction, where aquifiers are being over-exploited, ensuring sustainable livelihoods of the vulnerable and poor are safeguarded. Poverty reduction strategies for areas where groundwater is being over-exploited.DescriptionProject Background: Groundwater is the principal source of both irrigation and domestic water supplies in many arid and semi-arid countries. However, many of these countries ...
Aim of this study was to evaluate the sensitivity of virtual colonoscopy (CT colonography) in the identification of colorectal cancer and to define the limitations and the advantages of this imaging modality, as well as indications to the examination. It was examined prospectively 62 symptomatic patients aged 36 to 82 years (28 women and 34 men). All patients underwent both conventional and virtual colonoscopy on the same day; the conventional examination allowed exploration of the entire colon. Conventional colonoscopy identified 89 lesions 3-50 mm in diameter, namely 84 benign and 5 malignant lesions. No lesions were identified in 12 patients. CT colonography identified 52 of the 89 lesions, with 57.1% diagnostic accuracy. They were 11 false positives (82.5% positive predictive value and 52.2% specificity) and 37 false negatives (24.5% negative predictive value and 58.4% sensitivity). Sensitivity was significantly higher (85.7%) for polyps #>=# 1 cm. Virtual ...
In this paper, we put forward a systematic method to analyze, control and evaluate the safety issues of medical robotics. We created a safety model that consists of three axes to analyze safety factors. Software and hardware are the two material axes. The third axis is the policy that controls all phases of design, production, testing and application of the robot system. The policy was defined as hazard identification and safety insurance control (HISIC) that includes seven principles: definitions and requirements, hazard identification, safety insurance control, safety critical limits, monitoring and control, verification and validation, system log and documentation. HISIC was implemented in the development of a robot for urological applications that was known as URObot. The URObot is a universal robot with different modules adaptable for 3D ultrasound image-guided interstitial laser coagulation, radiation seed implantation, laser resection, ...
Surface compositional changes in GaAs due to RF plasmas of different gases have been investigated by XPS and etch rates were measured using AFM. Angular Resolved XPS (ARXPS) was also employed for depth analysis of the composition of the surface layers. An important role in this study was determination of oxide thickness using XPS data. The study of surface - plasma interaction was undertaken by correlating results of surface analysis with plasma diagnosis. Different experiments were designed to accurately measure the BEs associated with the Ga 3d, Ga 2p sub 3 sub / sub 2 and LMM peaks using XPS analysis and propose identification in terms of the oxides of GaAs. Along with GaAs wafers, some reference compounds such as metallic Ga and Ga sub 2 O sub 3 powder were used. A separate study aiming the identification of the GaAs surface oxides formed on the GaAs surface during and after plasma processing was undertaken. Surface compositional changes ...
Union Oil Company drilled four geothermal test wells in the Cove Fort-Sulphurdale KGRA between 1975 and 1979. A fairly complete suite of well logs were recorded for the three deeper holes, and these data are presented as composite well log plots in this report. The composite well log plots have facilitated the interpretation of limestone, dolomite, sandstone, quartz-monzonite, serpentine, and volcanic lithologies and the identification of numerous fractures. This has been especially helpful because of the extensive lost circulaton zones and poor cuttings recovery. Intraformational flow was identified by a fluid migration-temperature tracer log at depth in CFSU 31-33. Well log crossplots were computed to assist in lithologic identification and the determination of physical properties for specific depth intervals in a given hole. The presence of hydrous minerals sometimes results in neutron porosity somewhat higher than the true nonfracture ...
This report describes the sampling and chemical analyses of smoke gas components for combustion performed in the SP Industry Calorimeter, where continuous measurements of oxygen, carbon dioxide and carbon monoxide are an integrated part of the Calorimeter system. On-line measurements of nitrogen oxides and total amounts of unburnt hydrocarbons were performed. Hydrogen cyanide, hydrogen chloride and ammonia in the smoke were sampled and absorbed in impinger bottles and subsequently analyzed using wet chemical techniques. An adsorbent sampling system was designed to allow the identification and quantitative analysis of individual organic compounds in the smoke. Gas chromatography was utilized with a mass spectrometric detector for the identification and a FID for quantification of the total amounts as well as individual components. A procedure for cleaning the smoke gas duct in between the combustion experiments was designed and found to be ...
AMS is a particle detector designed to perform high precision measurements of the cosmic rays fluxes with the main goals of searching for anti-nuclei, as remnants of primordial anti-matter, and of measuring the faintest components of the cosmic flux, anti- protons, positrons and high energy photons. To fulfill the requirements of large acceptance, long exposure time and excellent particle identification needed to achieve the intended results, AMS will operate in space as an attached payload to the International Space Station (ISS), being the first full featured particle physics experiment to operate in the Earth orbit. The AMS-02 accurate measurements of cosmic-ray nuclei, protons, antiprotons, electrons and positrons will be completed by high energy gamma rays detection. The experiment will detect gamma-rays, either by reconstructing e+e? pairs generated by photons converted upstream the tracker (conversion mode), or based on direct ...
A multivariate adaptive power system stabilizer is proposed. The advantages of using coordinated governor and excitation control are discussed, and the problems associated with constant parameter power system stabilizers (CPSS) are highlighted. The proposed multi-input multi-output (MIMO) power system stabilizer can coordinate the governor and excitation control and can overcome the problems associated with CPSS in power system stabilization. Selective multivariable state modelling, identification and control methods are investigated and the MIMO least squares technique with variable forgetting factor is used for system identification, guaranteeing good parameter tracking after a disturbance. Two multivariable self-tuning algorithms are investigated, the generalized minimum variance control and pole-shifting control algorithms. The multivariable self-searching pole-shifting algorithm is developed. Models of a single machine connected to an ...
Seven types of shellfish were irradiated by gamma ray at doses of 0, 3 and 6 kGy. Pulse photo-stimulated luminescence (PPSL) and thermoluminescence (TL) methods were employed to detect the radiation treatment. The screening of irradiation was carried out by the PPSL method followed by identification using the TL technique. Most of the irradiated shellfish were screened out correctly and only a few showed photon counts a bit higher than the lower threshold value by much lower than the upper threshold value. The TL method was employed using minerals isolated from all the control and irradiated shellfish samples by density gradient treatment. Three parameters, integrated intensities of first glow curves (TL1), ratios of first to that of second glow curves (TL1/TL2), and the shapes of maxima of first glow curves, were utilized for the identification of gamma ray treatment of shellfish. (author)
In this article we describe the identification of endophytic bacteria belonging to three groups isolated from shoot tip cultures of banana cv. Grand Naine in a recent study (Thomas et?al. 2008) based on partial 16S rRNA gene sequence homology analysis. The first group included banana stocks that displayed obvious colony growth on MS based tissue culture medium during the first in?vitro passage. The second group constituted stocks that were tissue index-negative for cultivable bacteria initially but turned index-positive after a few to several (4?8) in?vitro passages while the third group formed one sub-stock that turned index-positive after about 18 passages. The organisms belonged to about 20 different genera comprising of ?, ?, ?-proteobacteria, Gram-positive firmicutes and actinobacteri...
This Current Year Work Plan presents a detailed description of the activities to be performed by the Joint Integration Office during FY87. It breaks down the activities into two major work areas: Program Management and Program Analysis. Program Management is performed by the JIO by providing technical planning and guidance for the development of advanced TRU waste management capabilities. This includes equipment/facility design, engineering, construction, and operations. These functions are integrated to allow transition from interim storage to final disposition. JIO tasks include program requirements identification, long-range technical planning, budget development, program planning document preparation, task guidance, task monitoring, information gathering and task reporting to DOE, interfacing with other agencies and DOE lead programs, integrating public involvement with program efforts, and preparation of program status reports for DOE. Program Analysis is ...
I present here a review of past and present multi-disciplinary research of the Pittsburgh Computational AstroStatistics (PiCA) group. This group is dedicated to developing fast and efficient statistical algorithms for analysing huge astronomical data sources. I begin with a short review of multi-resolutional kd-trees which are the building blocks for many of our algorithms. For example, quick range queries and fast n-point correlation functions. I will present new results from the use of Mixture Models (Connolly et al. 2000) in density estimation of multi-color data from the Sloan Digital Sky Survey (SDSS). Specifically, the selection of quasars and the automated identification of X-ray sources. I will also present a brief overview of the False Discovery Rate (FDR) procedure (Miller et al. 2001a) and show how it has been used in the detection of ``Baryon Wiggles'' in the local galaxy power spectrum and source identification in radio data. ...
A broad range of persistent organic pollutants (POPs) and selected heavy metals has been analysed in sediment cores of North-East Germany. The pollutants analysed include polychlorinated dioxins and furans (PCDD/Fs), polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), several pesticides (DDT, HCH, CBz) and its metabolites as well as selected heavy metals. The sediment cores were sampled at five locations, reflecting a range of anthropogenic influences and background contamination: Arkona Basin (AK) representing a remote marine site, Lake Bugsin (BS) a background location only with atmospheric deposition, Lake Quenz (QS) close to the industrial city of Brandenburg, Teltowkanal (TK) in the suburban-industrial zone of Berlin and Lake White (WS) in the centre of Berlin. The age of the lower part of the AK, BS and TK cores were dated at 100-150 years. Results of selected pollutants (PCDD/Fs) have been presented earlier, focussing on the depth profile and the pollutant ...
Current regulations guiding technical aspects of natural resource damage assessments combine source, exposure pathway, resource injury, and monetary damage components. In order to associate any observed injury to the uncontrolled release of chemicals (e.g. oil spills, contaminated sediments, in-place toxics, etc.), it is important to link the chemical ''release'' to the injured resource. In complex environmental settings where multiple sources of similar chemicals are combined, multicomponent chemical methods must be used to link the release to the environmental distribution of chemicals. Three examples of the utility of multicomponent organic chemical analyses linked to comprehensive and representative sampling strategies will be discussed--the Shell Martinez Refinery oil spill, the Exxon Valdez oil spill, and a contaminated sediment assessment. These NRDA-based source identifications are based on use of polycyclic aromatic hydrocarbons, nitrogen and ...
Pulmonary tumors in children are rare. Nevertheless, there are besides malign primary neoplasms and metastases also some benign tumors that the radiologist should know. The identification of some tumors is difficult, since some of them may mimic pulmonary inflammation. The first diagnostic tool is chest radiography. After that, a CT with contrastmedium should be performed, if possible a multislice-CT (MSCT). Identification of mediastinal structures is best with MRI. (orig.) [German] Tumoren der Lunge sind im Kindesalter selten. Trotzdem finden sich neben den malignen primaeren und sekundaeren Raumforderungen auch im Kindesalter immer wieder benigne Tumoren, die der Radiologe kennen sollte. Eine eindeutige Identifizierung kann schwierig sein, da z. B. entzuendliche Infiltrate vorgetaeuscht werden koennen. Die primaere Untersuchungsmethode ist das konventionelle Thoraxroentgen. Die weitere Diagnostik muss mit der Computertomographie, nach ...
The automotive paints could be generally differentiated by color, layer sequence and chemistry of the paint layers comprising each of the topcoat and the primer system. The successful identification of hit-and-run a and traffic accidental vehicles from evidential paint fragments is greatly facilitated with a comprehensive laboratory collection of reference paint samples and the technique for direct analysis without sample preparation. The Pyrolysis-Gas Chromatography(PGC) is a precise and reliable method for performing both quantitative and qualitative analysis of polymeric materials and forensic samples. Our Forensic Laboratory is conducting the examination and identification of 73 reference paint samples; 4 colors of each domestic automotive make that is poplar in Korea, by Curie Point Pyrolyzer(JHP-3) and GC with capillary column(ultra alloy-5). This method can be used not only to compare paint traces with their suspected sources, but also ...
We review recent development in separations and mass spectrometric instrumentation for sensitive and high-throughput proteomic analyses. These efforts have been primarily focused on the development of high-efficiency (separation peak capacity of ~103) nanoscale liquid chromatography (nanoLC; e.g., flow rates extending down to ~20 nL/min at optimal separation linear velocities through narrow packed capillaries) in combination with advanced mass spectrometry (MS), including high sensitivity and high resolution Fourier transform ion cyclotron resonance (FTICR) MS. This technology enables MS analysis of low nanogram-level proteomic samples (i.e., nanoscale proteomics) with individual protein identification sensitivity at the low zeptomole-level. The resultant protein measurement dynamic range can reach 106 for nanogram-sized proteomic samples, while more abundant proteins can be detected from complex sub-picogram size proteome samples. The average proteome ...
We have developed a Bragg curve counter (BCC) equipped with an active cathode to extend the energy acceptance to lower energies than for a conventional BCC to measure differential cross-sections of fragment production reactions induced by tens of MeV protons. The signal from the active cathode providing the timing signal of fragment incidence and the time difference signal between the cathode and anode gives information on the fragment range in the BCC on the basis of electron drift time. Utilization of the range information made possible identification of fragments less than 0.5 MeV/u that is lower than the identification threshold of a conventional BCC technique. After investigations on fundamental properties of a newly constructed BCC using heavy ion beams and alpha-particles, this method was applied successfully to a fragment production measurement for 70 MeV proton-induced reactions on carbon. With this technique, the energy threshold of ...
During the phases of separation, treatment, conditioning and storage of radioactive waste, destructive and nondestructive methods for their characterization are needed. In order to satisfy this necessity, in the frame of the National Program of Research and Development, the 'Laboratory for characterization of spent nuclear fuel and high/medium level radioactive waste- LABORAD' was created. The purpose of the project was to accredit the analysis methods available in the laboratory, and also to develop new methods for the characterization of the radioactive waste. A special attention was paid to the high-level radioactive waste and spent nuclear fuel characterization that require special facilities for handling. These facilities (e.g. hot cells, remote handlers, transport container) are already available in our institute. Experimental results and performances obtained during validation of the methods are ...
The Department of Energy`s Office of Technology Development initiated an Integrated Demonstration Program at the Savannah River Site in 1989. The objective of this program is to develop, demonstrate, and evaluate innovative technologies that can improve present-day environmental restoration methods. The Integrated Demonstration Program at SRS is entitled ``Cleanup of Organics in Soils and Groundwater at Non-Arid Sites.`` New technologies in the areas of drilling, characterization, monitoring, and remediation are being demonstrated and evaluated for their technical performance and cost effectiveness in comparison with baseline technologies. Present site characterization and monitoring methods are costly, time-consuming, overly invasive, and often imprecise. Better technologies are required to accurately describe the subsurface geophysical and geochemical features of a site and the nature and extent of contamination. More efficient, nonintrusive ...
A basic problem in gravitational physics is the resolution of spacetime singularities where general relativity breaks down. The simplest such singularities are conical singularities arising from orbifold identifications of flat space, and the most challenging are spacelike singularities inside black holes (and in cosmology). Topology changing processes also require evolution through classically singular spacetimes. I briefly review how a phase of closed string tachyon condensate replaces, and helps to resolve, basic singularities of each of these types. Finally I discuss some interesting features of singularities arising in the small volume limit of compact negatively curved spaces and the emerging zoology of spacelike singularities.
The SRP Baseline Hydrogeologic Investigation was implemented for the purpose of updating and improving the knowledge and understanding of the hydrogeologic systems underlying the SRP site. Phase III, which is discussed in this report, includes the drilling of 7 deep coreholes (sites P-24 through P-30) and the installation of 53 observation wells ranging in depth from approximately 50 ft to more than 970 ft below the ground surface. In addition to the collection of geologic cores for lithologic and stratigraphic study, samples were also collected for the determination of physical characteristics of the sediments and for the identification of microorganisms.
The following are reported: colorimetric determination of Ti in Cr, decontamination of metals by anodic dissolution, computer code for x-ray peak identification, gel-permeation chromatography of CoRezyn 1664 polyester resin, infrared monitoring of gases and vapors, particle size analysis of dusts, nondestructive analysis of Oralloy for removable alpha contamination, dissolution (digestion) of high-fired oxides, assay of U in a Pu-U alloy, measurement of oxide thickness on Pu metal by x-ray diffraction, analysis of precipitated Pu peroxide, differentiation of Dowex SBR and 11 resins, and determination of Pu solubility in simulated lung fluid.
The purpose of-this planning guide is to present the process used to identify, document, and control PFP Stabilization and Deactivation Project interfaces. Revisions to this document will include, as attachments, the most recent version of the Project Interface Management List. A preliminary Interface Management List is included in Appendix A. This document is intended be a Project owned management tool. As such, this document will periodically require revisions resulting from improvements of the information, processes, and techniques as now described. For most revisions that suggest improved processes, PFP management approval is all that will be required.
This paper presents the eigenvalue control strategy which utilizes an adaptive power system stabilizer for the decentralized control of damping and frequency of electromechanical oscillations in power systems. The control procedure includes the complete identification of the decoupled subsystem model in real-time from local measurements only and the assignment of its estimated electromechanical eigenvalue by the change of stabilizer parameters. The robustness and efficiency of the proposed adaptive controller to enhance overall system stability are illustrated in several examples, including the three-machine power system model.
This bibliography contains citations concerning Federal and state laws and management programs for the protection and use of inland wetlands. Utilization of wetlands to control highway runoff and community waste water is discussed. Wetlands protection programs, restoration projects, resource planning, and wetlands identification methods are cited. References to coastal and salt-water wetlands are excluded from this bibliography. (This updated bibliography contains 219 citations, 37 of which are new entries to the previous edition.)
This report presents an overview of research activity currently being funded by the US Department of Energy (DOE) on solid wastes from coal gasification, coal liquefaction, and oil shale technologies, Projects conducted in the DOE energy technology centers and national laboratories, and in cooperative projects with other government agencies, private industry, and universities are developing the basic and applied technology and data on which present and future fuel-conversion and utilization processes depend. The report identifies data gaps and recommends research needs where warranted.
A database has been compiled on human dietary intakes of trace elements by populations groups living in various countries. The main sources of information used were (1) publications in the open scientific literature, and (2) data submitted to the IAEA in response to a questionnaire. The database contains 1,758 intake values covering 35 elements and 47 countries. In this report the data are listed in various ways to facilitate identification of intake values for any specified country, element and population group. 4 refs, 5 tabs.
In the quest to understand the ultimate nature of WIMPs, we propose the use of a hybrid detection technique: cylinders filled with liquefied noble gasses, acting as targets, are immersed inside a tank of Gd-doped ultra-pure water that provides an active and efficient veto against neutrons. The evaluation of the background rejection capabilities and physics potential of this instrument have been carried out through a full GEANT4 simulation, assuming the detector will be located at the Canfranc underground laboratory (in the Spanish Pyrenees). Our results compare very favourably with existing or planned experiments in the field. This technique is scalable and will allow to reach target masses of few tonnes in the next future.
Source-term codes to predict the release of radionuclides from nuclear waste packages have been developed and implemented worldwide. A survey and initial comparison of the attributes and capabilities of 13 international source-term codes was recently completed. This preliminary analysis focused on comparison of transport factors/processes and solution methods. This initial comparison is a necessary first step in a properly-conceived, systematic benchmarking of source-term codes. Advantages of such a comparison include assurance of the mathematical correctness of implemented models, comparison and quantification of variances introduced by different types of simplifications, and identification and quantification of the impact of near-field processes.
Sufficient discussion of the elements of the leasing and permitting programs is included to place the information developed in proper context. A table and process flow diagram developed previously which outline the steps in the non-competitive leasing process, is reprinted. Computer printout profiles are presented on 195 identifiable areas in the following states: Arizona, California, Colorado, Idaho, Montana, Nevada, New Mexico, Oregon, Utah, Washington, and Wyoming. Sufficient information on the boundaries of these areas is contained in the report to permit identification of their general location on any map of the appropriate state which shows township and range locations.
With the mentioned method to analyse O-tyrosine with HPLC/fluorescence-detection, the irradiation of chicken meat can be determined in a simple and fast way. The formation of o-tyrosine is proportional to the applied dose but because it is also depending on the applied dose rate and the temperature during the irradiation, it is not possible to control the irradiation dose. Since unirradiated chicken can contain little amounts of o-tyrosine and to confirm some results, a second method is needed. Together with one of the other mentioned methods (analysis of the volatiles or esr-spectroscopy) it is possible to recognize irradiated chicken with a high security. (author).