and antibody responses of rhesus macaques exposed to the human gammaretrovirus XMRV. J Virol. 2011 May ;85(9):4547-57. Epub 2011 Feb 16 . PubMed Your browsing activity is...
IntroductionHealth information on the Internet undergoes no quality control at the stage of production, thus its quality is highly variable, making it difficult...Full Text Available
MD, Chief, Division of Endocrinology, Diabetes and Metabolism, Trinitas Regional Medical Center, Elizabeth, NJ. Review provided by VeriMed Healthcare Network. Also reviewed...
Waermedurchgang, Blutzucker, Muskel- and Leberglykogen sowie auf die chemische Thermogenese juveniler Albino- ratten" .. Acta biol. med. germ., Vol. ...
She completed Northern Arizona University's post-baccalaureate program, and received her M.E.d from Arizona State University with a focus in cognitive ...
... time, sucrase activity, a marker of intestinal epithelium (Matsushita, 1983) was observed in epithelial cells with CdxA ... PubMed, CSAIshii, Y., K. Fukuda, H. Saiga, S. Matsushita, and S. Yasugi. 1997. E...
and antibody responses of rhesus macaques exposed to the human gammaretrovirus XMRV. J Virol. 2011 May ;85(9):4547-57. Epub 2011 Feb 16 . PubMed Surgical staging of early...
Jeltes, R., Burghardt, E., and Breman, J. (1971). Brit. J. industr. Med., 28, 96-99. Gas chromatographic determination of phosgene and dichloroacetylene in air. Phosgene and dichloroacetylene...Full Text Available
White, W. G., and Vickers, H. R. (1970).Brit. J. industr. Med.,27, 167-169. Diethyl thiourea as a cause of dermatitis in a car factory. Fifteen...Full Text Available
Crockford, G. W., Crowder, M., and Prestidge, S. P. (1972).Brit. J. industr. Med.,29, 378-386. A trace gas technique for measuring clothing microclimate...Full Text Available
In light of the recent rapid increase in the fossil fuel prices it is meaningful to evaluate the impact of these price changes in the economics of dual-purpose desalination projects producing electricity and fresh water simultaneously. The price of crude oil and LNG (Liquefied Natural Gas) has increased by about 200% and 100% during the past three or four years. The uranium price has also increased by nearly 500% during the same period. The purpose of this paper is to analyze and compare the economics of SMART (System-integrated Modular Advanced ReacTor) which is being developed as a small size PWR type and the LNG Combine Cycle coupled with MED (Multi-Effect Distillation) which are being acknowledged as promising energy sources for the future in Korea. The methods of analysis used in this paper are the lifetime leveled cost method for the power and water cost calculation and the power credit method for the total cost allocation. DEEP (Devaluation Economic ...
In light of the recent rapid increase in the fossil fuel prices it is meaningful to evaluate the impact of these price changes in the economics of dual-purpose desalination projects producing electricity and fresh water simultaneously. The price of crude oil and LNG (Liquefied Natural Gas) has increased by about 200% and 100% during the past three or four years. The uranium price has also increased by nearly 500% during the same period. The purpose of this paper is to analyze and compare the economics of SMART (System-integrated Modular Advanced ReacTor) which is being developed as a small size PWR type and the LNG Combine Cycle coupled with MED (Multi-Effect Distillation) which are being acknowledged as promising energy sources for the future in Korea. The methods of analysis used in this paper are the lifetime leveled cost method for the power and water cost calculation and the power credit method for the total cost allocation. DEEP (Devaluation Economic ...
Radiation doses to workers at the Manhattan Engineer District (MED) and US Atomic Energy Commission (AEC) sites due to external irradiation during 1940--1960 are reviewed. Categorized radiation dose data were available from AEC annual reports for some years. Annual individual radiation dose data for ten MED/AEC sites for all years were available from the US Department of Energy`s (DOE) Comprehensive Epidemiologic Data Resource (CEDR). These data are combined to produce an estimate of external collective dose equivalent to 172,000 person-rems (1720 person-Sv) for 1940--1960. During this period there were 41 overexposures, 19 criticality incidents, and 3 deaths due to acute radiation syndrome among several hundred thousand workers.
The Formerly Utilized Sites Remedial Action Program (FUSRAP) is to evaluate the radiological conditions at former MED-US AEC sites. Purpose of the Ocean FUSRAP program is to assess the feasibility of ocean disposal of FUSRAP waste which contains trace natural radioactive materials. This paper presents soil characterization information on the Middlesex, NJ, Sampling Plant site, and reports preliminary ocean dispersion calculations. (DLC)
A new type of impregnation jelly can be used instead of traditional oil may reduce the formation of cavities in marine high-voltage direct current cables. This provides a foundation for the development of cables with improved insulation and for higher power. This was a conclusion of the Norwegian ''EFFEKT''-project. Using the jelly reduces the size of the cavities substantially and no discharges seem to occur during formation, growth and collapse of cavities. It is also environmentally friendly, since there is no leakage of oil.
Abstract Objective: This study aims to gain an overview of hot topics related to research focused on Chinese herbal drugs by authors inside China and outside of China in the past 10 years. Methods: PubMed/MEDLINE was utilized in order to investigate and select research that was published on ?Chinese herbal drugs?? from 1998 to 2007, by authors located both inside and outside of China (MeSH terms were downloaded and ranked). MeSH terms that frequently appeared were identified and co-word analysis was carried out for two groups: (1) authors located in China, and (2) authors based outside of China, respectively. The hot topics concerning research into Chinese herbal drugs were concluded after cluster analysis and related document analysis. Results: For authors in the China group versus those ...
Abstract Introduction: The obstructed, infected kidney is a urological emergency. It has been accepted that the management of infected hydronephrosis secondary to ureteric stones is through prompt decompression of the collecting system. However, the optimal method of decompression has yet to be established. Materials and Methods: A PubMed and Medline search was performed of all English-language articles from 1960 using key words ?sepsis,?? ?urosepsis,?? ?obstruction,?? ?obstructive pyelonephritis,?? ?pyonephrosis,?? ?infection and hydronephrosis?? ?decompression,?? ?stent,?? ?nephrostomy,?? and ?management.?? The Cochrane database and National Institute for Clinical Effectiveness guidelines were searched using the terms ?sepsis,?? ?urosepsis,?? ?stent,?? ?nephrostomy,?? or ?obstruction.?? ...
Periureteral or subtrigonal injection of dextranomer/hyaluronic acid (Dx/HA) copolymer (Deflux, Q-Med, Uppsala, Sweden) is an increasingly common endoscopic treatment for vesicoureteral reflux. We report a confusing radiographic finding of bilateral calcified Dx/HA injections initially thought to represent bilateral distal ureteral stones in a boy who presented with intermittent periumbilical pain. Urologists, radiologists, and emergency room physicians should be aware of the potential for calcification of ureteral implants of Dx/HA, and of the potentially confusing radiographic images that may result. (orig.)
Receptor interacting protein 140 (RIP140) is a coregulator for numerous nuclear receptors and transcription factors and primarily exerts gene-repressive activities on various target genes. We previously identified a spectrum of posttranslational modifications on RIP140 that augment its property and biological activity. In T(3)-triggered biphasic regulation of cellular retinoic acid binding protein 1 (Crabp1) gene along the course of fibroblast-adipocyte differentiation, we found TRAP220(MED1) critical for T(3)-activated chromatin remodeling whereas RIP140 essential for T(3)-repressive chromatin remodeling of this gene promoter. In this current study, we aim to examine whether and how RIP140 replaces TRAP220(MED1) on the CrabpI promoter in differentiating adipocyte cultures. We find increasing recruitment of RIP140 to this promoter, with corresponding reduction in TRAP220(MED1) recruitment during the T(3)-repressive phase. ...
The spectre of exclusionary medical service provision, restricted clinic access and physician targeting in sectarian-divided Iraq underscores the crucial and timely need for qualitative research into the inter-relationship between conflict, identity and health. In response, this paper provides a critical ethnography of obstetric service provision and patient access during Shia-Sunni hostilities in Gilgit Town, capital of Pakistans Northern Areas (2005). I analyse how services were embedded in and constrained by sectarian affiliation in ways that detrimentally impacted Sunni women patients and hospital staff, resulting in profoundly diminished clinic access, reduced physician coverage and a higher observed incidence of maternal morbidity and mortality. The paper first situates obstetric med...
In children and adolescents the Second Generation Antipsychotics (SGAs) represent the class of psychotropic drugs whose use has grown more significantly in recent years: they are primarily used for treatment of patients with disruptive behavior disorders, mood disorders and pervasive developmental disorders or mental retardation. In order to compare the efficacy and tolerability of antipsychotics against placebo or each other, a systematic Medline/PubMed search for randomized, double blind studies on SGA in patients younger than 18years of age at enrolment, was conducted. Papers on schizophrenia, discussed in another article of this specific issue, were excluded by the efficacy analysis. A set of standard efficacy and safety indices, such as treatment effect sizes (ES), the Numbers Needed ...
Summary Objective To find out whether there was over-reporting of SARS patients in mainland China in view of the relatively low case fatality ratio in mainland China, in comparison with other affected countries and areas. Methods We searched PubMed for all SARS antibody detection papers (in English or Chinese language) using the keywords `SARS' and `antibody'. Then the resulting articles were further read through to select the SARS detection results using ELISA methods of serum samples collected at least 1 month after disease onset. A multi-level logistic regression was applied to test for possible differences in the proportions positive between locations of the study. Results A total of 48 studies were identified, including 39 from mainland China and nine from elsewhere (Hong Kong, Taiwan...
Objective This report investigates epidemiologically whether exposure to silica is associated with lung cancer risks in individuals without silicosis. Methods We searched the PubMed reference data base from 1966 through 1/2007 for reports of lung cancer in silica-exposed persons without and with silicosis. To explore heterogeneity between studies, a multi-stage strategy was employed. First, fixed-effect summaries (FES) and corresponding 95% confidence intervals (CI) for various combinations of studies were calculated, weighting individual results by their precision. The homogeneity of the contributing results was examined using ?2 statistics. Where there was evidence of substantial heterogeneity, the CI around the FES was increased to take account of the between-study variability. Random-e...
The potential association between xenotropic murine leukaemia virus-related gammaretrovirus (XMRV) and prostate cancer (PCa) has been documented since 2006. It is important for furthering our understanding of the biological mechanisms of PCa to ascertain whether this association is causal. To summarize the available information on the epidemiological and laboratory findings of the association, we conducted a literature search of the PubMed electronic database (from March 2006 to February 2011) to identify relevant published studies that examined the association between XMRV and PCa. Although several studies showed the positive association between XMRV and PCa, more recent studies did not support this conclusion. The positive findings might be due to contamination of human samples. Further ...
Bimaxillary protrusion is prevalent among Asians and anterior segmental osteotomies are commonly used for its surgical correction. The objective of this study was to evaluate the soft tissue changes resulting from anterior segmental osteotomies. The electronic databases PubMed, Scopus and ISI Web of knowledge were searched for potentially eligible studies using a set of predetermined keywords. Full texts meeting the inclusion criteria were retrieved and their references were manually searched for additional relevant articles. The study details and outcome data of these reports were extracted using spreadsheets for comparison. The methodological quality of each study was assessed. Eleven studies met the inclusion criteria. Lateral cephalometry was used in all studies. A reduction of the lab...
Conformationally constrained analogue synthesis was undertaken to aid in pharmacophore mapping and 3D-QSAR analysis of nitrobenzylmercaptopurine riboside (NBMPR) congeners as equilibriative nucleoside transporter 1 (ENT1) inhibitors. In our previous study [J. Med. Chem. 2003, 46, 831-837], novel regioisomeric nitro-1,2,3,4-tetrahydroisoquinoline conformationally constrained analogues of NBMPR were synthesized and evaluated as ENT1 ligands. 7-NO2-1,2,3,4-Tetrahydroisoquino-2-yl purine riboside was identified as the analogue with the nitro group in the best orientation at the NBMPR binding site of ENT1. In the present study, further conformational constraining was introduced by synthesizing 5prime-O,8-cyclo derivatives. The flow cytometrically determined binding affinities indicated that the...
The emission of air pollutants from road vehicles is the most significant source of air pollution in towns. The chemical composition of these pollutive substances is dependent on the fuel, the type of vehicle and the character of the traffic system. The pollution concentration was measured, (nitrogen oxides and carbon monoxide) in relation to each type of vehicle, in four streets in the Copenhagen area. The system of measurement used was the ''Operational Street Pollution Model'' (OSPM). Results are presented in the form of tables and charts. (AB) 11 refs.
Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobehavioral disorder afflicting adults worldwide. This article is an update on the evidence supporting medications for adult ADHD, with particular emphasis on cardiovascular implications. Relevant clinical literature was sought using PubMed searches, with an emphasis on new reports from April 2009 to April 2011. This review describes the efficacy and general tolerability of stimulant and nonstimulant medications for adults with ADHD as seen in contemporary clinical trials. Cardiovascular response to medications for ADHD is primarily seen in heart rate and blood pressure elevations, while less is known about the etiology of rare cardiovascular events or long-term sequelae. Further research is indicated to delineate clinical an...
Context. We present a multi-wavelength, high-resolution observational survey of the young binary system Haro 6-10 (GV Tau, IRAS 04263+2426), which is harbouring one of the few known infrared companions. Aims. The primary goal of this project is to determine the physical and geometrical properties of the circumstellar and circumbinary material in the Haro 6-10 system. Methods. High-resolution optical (HST/WFPC2) and near-infrared (VLT/NACO) images in different bands were analysed to investigate the large-scale structures of the material around the binary.Mid-infrared interferometry (VLTI/MIDI) and spectroscopy (TIMMI2 at the 3.6m ESO telescope) were carried out to determine the structure and optical depth of the circumstellar material around the individual components. Results. The multi-wavelength observations suggest that both components of the binary system Haro 6-10 are embedded in a common envelope. The measured extinction indicates a dust composition of the envelope similar to that ...
Objective: To review data on efficacy and safety of second-generation antipsychotics (SGAs) in children and adolescents with psychotic and bipolar spectrum disorders. Methods: Medline/PubMed/Google Scholar search for studies comparing efficacy and/or tolerability: (i) between two or more SGAs; (ii) between SGAs and placebo; and (iii) between at least one SGA and one first-generation antipsychotic (FGA). The review focused on three major side-effect clusters: 1. body weight, body mass index, and cardiometabolic parameters, 2. prolactin levels, and 3. neuromotor side effects. Results: In total, 34 studies with 2719 children and adolescents were included. Studies lasted between 3weeks and 12months, with most studies (79.4%) lasting 3months or less. Nine studies (n=788) were conducted in patie...
Chemical-looping combustion (CLC), has previously been studied as a method for separating CO{sub 2} during combustion of gaseous fuels. In this project the possibility to apply this process for direct use of solid fuels has been investigated. The following has been accomplished: A 10 kW reactor system for CLC with solid fuels has been designed and built. Tests with solid fuel and metal oxid particles in a laboratory reactor show that it is possible to oxidize solid fuels with metal oxide particles in cyclic testing, thus giving proof of basic concept. They also show how the reaction rate is affected by temperature, steam concentration etc., and, most important of all, that the rates of reaction are realistic. Tests with metal oxide materials available at low costs have been successful. Chemical-looping combustion with solid fuels has a potential to achieve very low costs for separation of CO{sub 2}, below 10 Euro/ton CO{sub 2}. In summary the studies of metal oxides and tests with ...
Burner for feeding a solid and a liquid or gaseous fuel to a kiln comprises a central supply pipe for liquid or gas surrounded concentrically by a first pipe providing an annular passage through which primary air is supplied. Concentrically surrounding that pipe is a second pipe providing an annular channel for supply of solid fuel in carrier air stream. The outlet end of the first concentric pipe is closed by a plate fixed mounted at the pipe end and providing multiple nozzles having their axes parallel to the burner axis. The surface of the plate facing the burning zone provides a divergence opening for the central pipe while the inner surface is formed with helical teeth. These are engaged by complementary teeth mounted on the end of the central pipe which is rotatable and biased by springs so that the teeth are in engagement. Rotation of the pipe causes relative axial motion of the teeth to create tangential slots for admission of primary air into the central pipe. The second ...
The purpose of the project is to further develop a Danish natural gas reformer system including optimisation of subsystems and the overall system consisting of a natural gas reformer and fuel cell CHP generator. This will contribute to the evaluation of to what extend Denmark shall develop small reformer units for PEM fuel Cells. In the project a reformer system with a high degree of automatic control has been build that fulfils the CHP requirements to operation time, dynamics etc. This work, with a FP05 reformer unit, has given valuable results concerning the possibilities and limitations of the reformer technology for CHP usage. It is important that the reformer and fuel cell units are designed with matching yields to optimise efficiency, turn-down start-up time etc. The burner that delivers heat for the steam reaction shall be able to use natural gas as fuel. This gives the possibility of using existing burner technology. In addition this will improve the efficiency since it will ...
Inferior vena cava (IVC) obstruction is a well-described clinical entity. Most IVC obstructions from malignant neoplasms are a direct result of tumor compression [Oviedo J, Cerda S. Vascular invasion by hepatocellular carcinoma. Arch Pathol Lab Med 2001;125: 454-5; Furui S, Sawada S, et al. Gianturco stent placement in malignant caval obstruction: analysis of factors for predicting the outcome. Radiology 1995;195:147-52; Fletcher WS, Lakin PC, et al. Results of treatment of inferior vena cava syndrome with expandable metallic stents. Arch Surg 1998;133:935-8]. The symptoms of IVC obstruction include progressive ascites, scrotal edema and lower body edema. These constellations of symptoms are described as IVC syndrome and are devastating to a patient with end-stage cancer. We describe a palliative therapy utilizing Luminexx nitinol self-expanding stents to treat intracaval hepatoma thrombus obstructing the IVC. The procedure is rapidly performed, technically ...
A new leaf-sequencing approach has been developed that is designed to reduce the number of required beam segments for step-and-shoot intensity modulated radiation therapy (IMRT). This approach to leaf sequencing is called continuous-intensity-map-optimization (CIMO). Using a simulated annealing algorithm, CIMO seeks to minimize differences between the optimized and sequenced intensity maps. Two distinguishing features of the CIMO algorithm are (1) CIMO does not require that each optimized intensity map be clustered into discrete levels and (2) CIMO is not rule-based but rather simultaneously optimizes both the aperture shapes and weights. To test the CIMO algorithm, ten IMRT patient cases were selected (four head-and-neck, two pancreas, two prostate, one brain, and one pelvis). For each case, the optimized intensity maps were extracted from the Pinnacle"3 treatment planning system. The CIMO algorithm was applied, and the optimized aperture shapes and weights were loaded back into ...
The project aim is to model the hybrid plant at Vaesthamnsverket in Helsingborg using artificial neural networks (ANN) and integrating the ANN models, for online condition monitoring and thermoeconomic optimization, at Vaesthamnsverket. The definition of a hybrid plant is that it uses more than one fuel, in this case a natural gas fuelled gas turbine with heat recovery steam generator (HRSG) and a biomass fuelled steam boiler with steam turbine. The project is a continuation of previous projects where ANN training was done with operational data from the plant. The ANN models have, if required, been updated to better suit the purpose of this project. The thermoeconomic optimization takes into account current electricity prices, taxes, fuel prices etc. and calculates the current production cost along with the 'predicted' production cost. The tool also has a built in feature of predicting when a compressor wash is economically beneficial. The user interface is developed ...
An add-on multileaf collimator for electrons (eMLC) has been developed that provides computer-controlled beam collimation and isocentric dose delivery. The design parameters result from the design study by Gauer et al (2006 Phys. Med. Biol. 51 5987-6003) and were configured such that a compact and light-weight eMLC with motorized leaves can be industrially manufactured and stably mounted on a conventional linear accelerator. In the present study, the efficiency of an initial computer-controlled prototype was examined according to the design goals and the performance of energy- and intensity-modulated treatment techniques. This study concentrates on the attachment and gantry stability as well as the dosimetric characteristics of central-axis and off-axis dose, field size dependence, collimator scatter, field abutment, radiation leakage and the setting of the accelerator jaws. To provide isocentric irradiation, the eMLC can be placed either 16 or 28 cm above the ...