AIMSTo evaluate and compare the risk of specific safety outcomes in patients prescribed ibuprofen and paracetamol concomitantly with those in patients prescribed ibuprofen or paracetamol...Full Text Available
Lipase catalyzed esterification of therapeutic drugs to functional self-assembled monolayers (SAMs) on 316L stainless steel (SS) after assembly has been demonstrated. SAMs of 16-mercaptohexadecanoic acid (-COOH SAM) and 11-mercapto-1-undecanol (-OH SAM) were formed on 316L SS, and lipase catalysis was used to attach therapeutic drugs, perphenazine and ibuprofen, respectively, on these SAMs. The reaction was carried out in toluene at 60 degrees C for 5 h using Novozyme-435 as the biocatalyst. The FTIR spectra after surface modification of -OH SAMs showed the presence of the C=O stretching bands at 1745 cm(-1), which was absent in the FTIR spectra of -OH SAMs. Similarly, the FTIR spectra after the reaction of the -COOH SAM with perphenazine showed two peaks in the carbonyl region, a peak at 1764 cm(-1), which is the representative peak for the C=O stretching for esters. The second peak at 1681 cm(-1) is assigned to the C=O stretching of the ...
Tau is a microtubule-associated protein that promotes microtubule assembly and stability. In Alzheimer's disease and related tauopathies, tau fibrillizes and aggregates into neurofibrillary tangles. Recently, oleocanthal isolated from extra virgin olive oil was found to display non-steroidal anti-inflammatory activity similar to ibuprofen. Since our unpublished data indicates an inhibitory effect of oleocanthal on A? fibrillization, we reasoned that it might inhibit tau fibrillization as well. Herein we demonstrate that oleocanthal abrogates fibrillization of tau by locking tau into the naturally unfolded state. Using PHF6 consisting of the amino acid residues VQIVYK, a hexapeptide within the third repeat of tau that is essential for fibrillization, we show that oleocanthal forms an adduct with the lysine via initial Schiff base formation. Structure and function studies demonstrate that the two aldehyde groups of oleocanthal are required for ...
It was shown that the incorporation of "1"4C-linoleic acid in cerebrosides of normal and psoriatic human skin is different. In psoriatic epidermis and corium the turnover of this fatty acid is significantly elevated. It is suggested that in psoriasis the epidermal cell is not able to build up a regular carbohydrate sequences of lipids because the false carbohydrate chain activates the degradation of glycolipids and in compensating for the increased degradation raises the synthesis rate of glycolipids. (orig./MG).
Patent ductus arteriosus (PDA) affects approximately 31% of infants whose birth weight is between 501 and 1500 g. The ductus arteriosus is a blood vessel that allows blood to bypass the pulmonary vasculature...Full Text Available
The uptake and incorporation of (/sup 3/H)adenine as a measure of total microbial (bacteria and unicellular algae) nucleic acid synthesis depends on the validity of several assumptions. A unique characteristic of the (/sup 3/H)adenine method is the ability to measure the specific radioactivity (nCi pmol/sup -1/) of the immediate precursor pool of the adenine incorporated into nucleic acids. This measurement permits correction for isotope dilution when the added radiotracer mixes with exogenous pools of structurally related compounds before uptake and with endogenous pools after transport into the cells. The immediate precursors to (/sup 3/H)adenine incorporation into cellular RNA and DNA are ATP and dATP. Since the intracellular dATP pool is in isotopic equilibrium with the ATP pool, one can determine the specific radioactivity of both precursor pools by measuring that of the ...
Changes in RNA synthesis in liver nuclei were observed at different ages and after hypophysectomy and hormone replacement in female Sprague-Dawley rats. As determined by the incorporation of [3H]UMP...Full Text Available
The incorporation of [14C]phenylalanine and [1,6-14C]shikimic acid into tyrosine was investigated in the callus of Portulaca grandiflora, var. JR (L.). By inhibiting...Full Text Available
Penicillic acid-negative mutants were obtained from a color mutant derived from Penicillium cyclopium NRRL 1888 through N-methyl-N'-nitro-N-nitrosoguanidine treatment. One mutant (SK2N6) accumulated 6-methyl-1,2,4-benzenetriol, which was not previously known to be a metabolite of P. cyclopium, in addition to orsellinic acid and orcinol. The radioactivity of [1-"1"4C]acetic acid was rapidly incorporated into 6-methyl-1,2,4-benzenetriol in a culture of P. cyclopium SK2N6. Moreover, the radioactivity of ["1"4C]6-methyl-1,2,4-benzenetriol was efficiently incorporated into penicillic acid in a culture of P. cyclopium NRRL 1888. These data indicate that 6-methyl-1,2,4-benzenetriol is a precursor for penicillic acid biosynthesis. The results on the addition of 1,4-dihydroxy-6-methoxy-2-methylbenzene, 6-methoxy-2-methylbenzoquinone (1,4), and ...
To eliminate their classical brittleness and flexibility problems zein films were plasticized by incorporation of different phenolic acids (gallic acid (GA), p-hydroxy benzoic acid (HBA) or ferulic acids (FA)) or flavonoids (catechin (CAT), flavone (FLA) or quercetin (QU)). The use of GA, CAT, FA and HBA at 3 mg/cm2 eliminated the brittleness of films and gave highly flexible films showing elongations between 135% and 189%, while FLA and QU caused no considerable effect on film elongation. The films containing FA and HBA showed extreme swelling and lost their structural integrity when hydrated in distilled water. In contrast, CAT and GA containing films maintained their integrity following hydration. Most of the GA (up to 93%) and a considerable portion of CAT (up to 60%) in the films exis...
Techniques of chemical analysis, amino acid sequencing and autoradiography are being used to study the frequency of incorporation of normally noncoded amino acids into hemoglobins and seminal fluid proteins. We are studying, by the sequencing of radiolabeled proteins followed by the recovery of ["3H] isoleucine phenylthiohydantoin by high-performance liquid chromatography, the frequency at which normally noncoded isoleucine is incorporated into hemoglobin because of base-substitution mutations versus translational errors. Irradiation increases the isoleucine content of human hemoglobin and the frequency of substitution of isoleucine for specific amino acids in rabbit hemoglobin. Studies to date indicate that these techniques have been developed sufficiently for initial analysis of the potential of drugs and environmental pollutants to induce base-substitution mutations in mammalian ...
The chemical fixation of tritium in stearic acid followed by embedding the tritiated stearic acid into an epoxy resin proved to be a good method for permanent waste disposal of tritium gas. Tc-126 and Tc-136 hardener were used for this purpose. The polymerization temperature of the polymer products was found to be highly decreased by adding stearic acid and slightly decreased by adding stearic acid or by raising the temperature of the leachant medium and slightly decreased by irradiation. On the other hand, small improvement in the compressive strength of the polymer products was achieved by adding silica powder. The polymer product showed high flame points above 573 K although it contains stearic acid. DTA and TG analysis indicate that the thermal stability of polymer products containing stearic acid and silica powder is better than samples containing only ...
Hyaluronic acid (HA), a principal matrix molecule in many tissues, is present in high amounts in articular cartilage. HA contributes in unique ways to the physical behavior of the tissue, and has been shown to have beneficial effects on chondrocyte activity. The goal of this study was to incorporate graduated amounts of HA into type I collagen scaffolds for the control of chondrocyte-mediated contraction and chondrogenesis in vitro. The results demonstrated that the amount of contraction of HA/collagen scaffolds by adult canine articular chondrocytes increased with the HA content of the scaffolds. The greatest amount of chondrogenesis after two weeks was found in the scaffolds which had undergone the most contraction. HA can play a useful role in adjusting the mechanical behavior of tissue engineering scaffolds and chondrogenesis in chondrocyte-seeded scaffolds.
Polymer-coated magnetic nanoparticles (MNPs) have been prepared and used as an immobilization matrix for the fabrication of solid-state tris(2,2prime-bipyridyl)ruthenium(II) (Ru(bpy)32+) electrogenerated chemiluminescence (ECL) sensor. The pre-synthesized maghemite (g-Fe2O3) MNPs were coated with poly(3-thiopheneacetic acid) based on an oxidative polymerization method using KMnO4. The poly(3-thiopheneacetic acid)-coated MNPs have formed the clusters with average diameter of 200-500nm. The multilayer films of poly(3-thiopheneacetic acid)-coated MNPs were uniformly formed on the surface of a Pt electrode by an external magnet. The Ru(bpy)32+ was rapidly incorporated into the multilayer films within 5min through the electrostatic interaction between the Ru(bpy)32+ and the negatively charged c...
Acid mine drainage represents one of the most important environmental problem facing the mining industry. If the tailings contain sulphur, acid mine drainage will be generated as soon as the tailings are exposed to oxygen. In this paper, the authors discussed a technique for the storage of acid mine drainage generating tailings that delays and even eliminates the occurrence. It was suggested that tailings should be piled by incorporating, at regular intervals, compacted waste rock. Thermal convection and diffusion will prevent oxygen from reaching the tailings, and limit water circulation. The modelling of transfer processes (heat, water, oxygen) in a well known tailings dump, the Doyon Mine, was performed, and the results compared to the modelling where compacted waste rock had been incorporated at regular intervals. The results indicated that by remaining saturated, the layers ...
Glycosaminoglycans synthesized by cultured rabbit smooth muscle cells were isolated after incorporation of (/sup 3/H)-glucosamine into glycosaminoglycans in the presence or absence of 10% fetal bovine serum. Glycosaminoglycans were quantitated by two-dimensional electrophoresis after proteolytic digestion of the cell layers and media. The results show that the presence of serum has no effect on the chondroitin sulfate, heparan sulfate and dermatan sulfate content of the cell layers. The incorporation of (/sup 3/H)-glucosamine into hyaluronic acid of the cell layers was three times higher in the presence of serum. In the medium , the quantity of hyaluronic was two times higher in the presence of serum while the other glycosaminoglycans remained unchanged. The incorporation of (/sup 3/H)-glucosamine into hyaluronic acid was unaffected by the presence of serum. Specific proteoglycans ...
The analysis described demonstrates the use of benefit/cost sensitivity analysis in examining the wide range of potential damages and savings associated with converting oil-fired electric utility boilers to burn coal in Florida. This model, for the first time incorporates, in quantitative terms, environmental economic externalities into a benefit/cost ratio sensitivity analysis framework. Five different dose-response estimates of morbidity and mortality costs, property devaluation, and willing-to-pay estimates are used in combination with four acid rain dose-response models to estimate the net present worth of externality costs. The model estimates the net present worth of benefits by incorporating into a dynamic framework all relevant construction, O + M, and fuel costs of converting an electrical generation facility from using oil to coal. These benefits of fuel savings are then weighted against various combinations of ...
We present evidence that the role of tryptophan and other potential intermediates in the pathways that could lead to indole derivatives needs to be reexamined. Two lines of Lemna gibba...Full Text Available
N-doped TiO2 has been prepared by use of sol?gel systems containing titanium alkoxide, with nitric acid as the nitrogen source. The time needed for gelation of the systems was drastically reduced by ultrasonic irradiation. The peaks assigned to the nitrate and nitrous ions were observed by FT-IR measurement during the sol?gel reaction. The N-doping was confirmed by the observation of N?O peaks in the XPS spectrum of the sample heated at 400??C. The nitrate ion acted as an oxidizer of the ethanol solvent and titanium species. The TiO2 became doped with nitrogen oxide species as a result of reduction of nitrate ion incorporated into the dried gel samples. These results indicated that the added nitric acid was reduced during the sol?gel transition and heating process, and the resulting NO spe...
Abstract Flame retardants (FRs) are used for in protection against fire. Organic inorganic hybrids could become one of the most promising FR solution in the future. In this paper, the synthesis, the characterization and the use as FRs and filler of grafted titania and alumina with 2 chloroethylphosphonic acid are presented. These hybrids contain 3.8 3.24% P and have good flame retardance when they are incorporated into unsaturated polyester resins. Alumina treated with 2 chloroethylphosphonic acid performed better than titania. The advantage of this approach is the use of these hybrid materials as filler and FR, in the same time, and the increase in flame retardancy by synergistic effect between alumina phosphorus and chlorine, for unsaturated polyester resins. Copyright 2010 John Wiley & ...
The French strategy of high level radioactive aqueous waste management is an incorporation in glassy fission products containers. Therefore, nitric acid soluble organic reagents needed for minor actinides and lanthanides selective separation from fission product solutions have to be sufficiently removed to reach carbon concentrations compatible with calcinator working. Thus, the ability of reagents to be oxidized under concentration conditions with or without denitration becomes a criteria of selection and have been studied. Further, if not working, other operations like hot hydrogen peroxide oxidation, catalyzed or not, are investigated. Reagents involved in this work are mainly complexing products (N-(2-Hydroxyethyl) Ethylene-diamine-tri-acetic Acid), pH keeping reagents (carboxylic acids like citric, glycolic, tartaric and lactic acid) and alkaline species (Tetramethylammonium ...
Summary In this study, antimicrobial activity of zein films incorporated with partially purified lysozyme and disodium ethylenediaminetetraacetic acid (Na2EDTA) has been tested on selected pathogenic bacteria and refrigerated ground beef patties. The developed films containing 700-g-cm-2 lysozyme and 300-g-cm-2 Na2EDTA showed antimicrobial activity on Listeria monocytogenes, Escherichia coli O157:H7, and Salmonella typhimurium. The application of lysozyme and Na2EDTA incorporated zein films on beef patties significantly decreased total viable counts (TVC) and total coliform counts after 5-days of storage compared to those of control patties (P-2EDTA or Na2EDTA alone significantly slowed down the oxidative changes in patties during storage (P-P-2EDTA for active packaging of refrigerated mea...
Various MLM-type (M, medium-chain fatty acids; L, long-chain fatty acids) structured triacylglycerols were produced in pilot- or small-scale packed-bed reactors by lipase-catalyzed acidolysis. The incorporation and acyl migration of octanoic acid were measured by gas chromatography and Grignard degradation, and ranged from 39.0 to 48.7% and 0.6 to 9.3%, respectively. Quantitation of triacylglycerol molecular species was performed by ammonia negative ion chemical ionization (NICI) mass spectrometry (MS). The proportion of ACN (acyl carbon number) 34 species that contained one C-18 fatty acid and two C-8:0, in samples analyzed, varied from 12.5 to 23.2%. The selected regioisomers MLM and MML within the ACN 34 species group were quantified by NICI tandem MS (MS/MS) and were in the range of 97.1 to 98.4% and 1.6 to 2.9%, respectively. There was no correlation between the level of acyl ...
Selective removal of hexavalent chromium ions from aqueous solutions using a chitosan/gold nanoparticles composite film was demonstrated. Localized surface plasmon resonance (LSPR) was used to measure the interface stability and detect the incorporation of chromium ions over time. The effects of pH, ethylenediaminetetraacetic acid (EDTA), and various foreign ions such as trivalent chromium, sodium, calcium, phosphate, sulfate and chloride on the adsorption of hexavalent chromium were investigated. PMID:19381379
The usefulness of radioiodination via demetallation of aryltrimethylsilanes was demonstrated. The radioiodination reaction was found to be very rapid and the regiospecific incorporation of radioiodine could be carried out with high radiochemical yields and high radiospecific activity. {sup 125}I-Labeled dimethylaminoethyl iodophenoxyacetate derivatives (5a-e), dimethylaminoethyl iodophenoxyacetamide derivatives (7a-c), iodophenoxyethyl ethylenediamine derivatives (9,14) and an iodophenoxyethylpiperazine derivative (18) were efficiently synthesized from the corresponding aryltrimethylsilyl intermediates (4a-e, 6a-c, 8, 13, 17) by this method. (author).
The usefulness of radioiodination via demetallation of aryltrimethylsilanes was demonstrated. The radioiodination reaction was found to be very rapid and the regiospecific incorporation of radioiodine could be carried out with high radiochemical yields and high radiospecific activity. "1"2"5I-Labeled dimethylaminoethyl iodophenoxyacetate derivatives (5a-e), dimethylaminoethyl iodophenoxyacetamide derivatives (7a-c), iodophenoxyethyl ethylenediamine derivatives (9,14) and an iodophenoxyethylpiperazine derivative (18) were efficiently synthesized from the corresponding aryltrimethylsilyl intermediates (4a-e, 6a-c, 8, 13, 17) by this method. (author).
In this study, we investigated the kinetics of linoleic acid production via lipase-mediated hydrolysis of corn DDGS oil in a batch reactor with continuous mechanical agitation and developed a kinetic model that incorporated the product inhibition to study the complete hydrolysis. The model agreed very well with observed data; though situations with low enzyme dosage or low stirring rates were modeled successfully without product inhibition, actual product concentration in such situations was too low to exert any inhibitory effects. Increasing the enzyme concentration increased hydrolysis, and beyond certain enzyme concentrations, effects tended to fade away because of excessive enzyme desorption from the interface. An enzyme dosage within the range of 40-60KLU/L of oil dispersion could be ...
Internal amplification controls (IACs) were constructed for incorporation into real-time nucleic acid amplification assays for bovine polyomavirus, hepatitis A virus, hepatitis E virus, human adenovirus, human norovirus genogroup I, human norovirus genogroup II, murine norovirus and porcine adenovirus. The addition of optimised amounts of IAC into the assays did not affect the limits of detection for each specific target virus. A poorly performed extraction of viral nucleic acids was simulated, and the effectiveness of IACs in identifying failed assays was demonstrated. The IACs constructed in this study can be reliably used in their specific assays to provide a robust control that can be routinely applied in the analysis of foods for viruses.
Biodegradable helicoidal stent prototypes made up of layers of poly-L-lactic acid (PLLA) and poly(L-lactic-co-glycolic acid) (PLGA) polymers were fabricated by temperature conditioning the stents at different stages of fabrication. The process incorporated elastic memory, or self-expandability in the stent, which is desirable to minimize stent recoil. The collapse pressures of such stents were studied, with and without in vitro degradation. The effects of thickness and the composition of each layer on the collapse pressure were modeled using the simple series model. Results of the in vitro studies for over 3 months showed that collapse pressure of the stents depended mainly on the degradation and other side-effects brought about by the degradation of different polymer compositions. General...
Fe-sheathed MgB{sub 2} tapes with cheap stearic acid, Mg stearate and Zn stearate doping were prepared through the in situ powder-in-tube method. It is found that J{sub c}, H{sub irr} and H{sub c2} were significantly enhanced by doping. Compared to the pure tapes, J{sub c} for all the doped samples was improved by more than an order of magnitude in a high-field regime. At 4.2 K, the transport J{sub c} reached 2.02 x 10{sup 4} A cm{sup -2} at 10 T for the Zn stearate doped tapes and 3.72 x 10{sup 3} A cm{sup -2} at 14 T for the stearic acid doped samples, respectively. Moreover, at 20 K, H{sub irr} for the Zn stearate doped tape achieved 10 T, which is comparable to that of the commercial NbTi at 4.2 K. The improvement of J{sub c}-H properties in doped samples can be attributed to the increase of H{sub c2} resulting from the incorporation of C atoms into the MgB{sub 2} crystal lattice as well as a high density of ...
Prostaglandin E2 (PGE2) has been shown to increase the synthesis of hyaluronic acid in cultured fibroblasts by increasing the activity of hyaluronate synthetase, a group of plasma membrane-bound synthetic enzymes. We examined whether PGE2 also increased the activity of those enzyme systems involved in the synthesis of sulfated glycosaminoglycan in the human embryonic lung fibroblast. Exposure of cells to PGE2 resulted in dose-dependent increases in glucosamine incorporation into all sulfated glycosaminoglycan subtypes. PGE2 at 10(-7) mol/L increased total glycosaminoglycan per dish to 21.6 +/- 3.1 micrograms versus 12.0 +/- 2.5 micrograms in control untreated cultures. Stimulation of endogenous PGE2 production by bradykinin had a similar effect on glycosaminoglycan synthesis. To examine whether PGE2 affected sulfated glycosaminoglycan protein core production, cells were labeled with tritiated glucosamine in the presence of cycloheximide. Under ...
The authors investigated the effect of T-2 toxin on rat liver mitochondrial protein synthesis. Isolated rat liver mitochondria were supplemented with an S-100 supernatant from rat liver and an external ATP-generating system. An in-vitro assay employing cycloheximide, and inhibitor of cytoplasmic protein synthesis, and chloramphenicol, and inhibitor of mitochondrial protein synthesis, to distinguish mitochondrial protein synthesis from the cytoplasmic process. Amino acidincorporation into mitochondria was dependent on the concentration of mitochondria and was inhibited by chloramphenicol. The rate of uptake of tritium leucine into mitochondrial protein was unaffected by the addition of T-2 toxin and was not a rate-limiting step in incorporation. However, 0.02 micrograms/ml of T-2 toxin decreased the rate of protein synthesis inhibition correlated with the amount of T-2 toxin taken up by the mitochondria. While T-2 toxin is ...
Bone matrix gelatin, prepared by sequential chemical treatment including decalcification with 0.6 N hydrochloric acid [9], was used as an alloimplant for the treatment of benign bone tumours, tumorous conditions of bone, acetabular dysplasia, delayed union, traumatic bone defects and other disorders. The bone matrix gelatin implanted into bone defects was incorporated successfully in 98% of implantations, excluding cases of infection, tumour recurrence and recurrence of tumorous conditions. The material was also implanted into ten bone sites as an onlay but in five it was resorbed without new bone formation. The incorporation of the bone matrix gelatin into the recipient bed was completed from 6 to 33 months (average 14.9 months) after implantation. Wound infection complicated 5 of 165 implantations (3%) in previously uninfected sites. Low grade fever persisting after the tenth post-operative day (a probable sign of ...
A series of cation exchange membranes was produced by impregnating and coating both sides of a quartz web with a Nafion solution (1100 EW, 10%wt in water). Inert filler particles (SiO_2, ZrO_2 or TiO_2; 5-20%wt) were incorporated into the aqueous Nafion solution to produce robust, composite membranes. Ion-exchange capacity/equivalent weight, water take-up, thickness change on hydration and ionic and electrical conductivity were measured in 1 mol dm"-"3 sulfuric acid at 298 K. The TiO_2 filler significantly impacted on these properties, producing higher water take-up and increased conductivity. Such membranes may be beneficial for proton exchange membrane (PEM) fuel cell operation at low humidification. The PEM fuel cell performance of the composite membranes containing SiO_2 fillers was examined in a Ballard Mark 5E unit cell. While the use of composite membranes offers a cost reduction, the unit cell performance was reduced, in practice, due ...
A stratigraphic and geochemical study of alpine soils, which formed in later Pleistocene (late glacial) and Neoglacial deposits in the Wind River Mountains of western Wyoming, indicates that these soils are affected by air-fall in flux of inorganic pollutants. Arsenic, bromine and antimony appear to have been deposited in surface soils by incorporation of aeolian materials which were presumably transported by winds from industrial sources, including coal-burning operations. As vanadium was not found in surface soils at concentrations above site-specific background levels, oil-fired energy generating stations were not found to be significant sources of surface soil pollution in the region. Acid-rain effects were not observed in the soils. (author) 32 refs.; 2 figs.; 3 tabs.
A widely used veterinary antibiotic, tetracycline (TC), has been incorporated in Langmuir-Blodgett (LB) films of dipalmitoylphosphatidic acid (DPPA) by means of two different procedures: co-transfer and incubation in solution. The resulting structures were characterized by means of contact angle and ellipsometric measurements. The presence of the antibiotic in the phospholipid film was evidenced by means of UV-Vis electronic absorption and infrared vibrational spectroscopy. The two sets of measurements unambiguously indicated the presence of the drug in the LB layer films obtained with both methods, although incubation led to a smaller content of immobilized tetracycline. In both cases, the drug was found to reside in the hydrophilic portion of the layers due to specific interactions of the dimethylamino group of the molecule with the polar head groups of the phospholipid.
Wood plastic composites are prepared under radiation of "6"0Co gamma source with simul, a low grade wood of Bangladesh using a water soluble monomer acrylamide (AM) mixed with a swelling solvent methanol, water or methanol/water (1:1) at different compositions in the presence of a number of additives and co-additives such as NVP (N-vinylpyrrolidone), TPGDA (tripropylene glycol diacrylate), TMPTA (trimethylol propane triacrylate), sulfuric acid, urea and copper sulfate. Polymer loading (PL) and tensile strength (TS) of the composites are measured. The role of these additives on the composites is also discussed. It is observed that nitrogen-atom containing-materials like urea, NVP and AM produce composites with the highest mechanical strength, and incorporation of copper into this system provides additional property of protection and preservation of the composites against attacks by insects and microbes. (author).
Summaries are included of research contracts which expired prior to Dec. 31, 1960. The contracts were concerned with investigations of: electrophysiological responses of biological systems in nerve cells to irradiation with small doses of ionizing radiations; the mode of the protective action of certain sulfhydryl compounds against radiation effects on the synthesis of deoxyribonucleic acid, using tritium-labeled thymidine; development of a bubble chamber method of monitoring and dosimetry for Low fast neutron fluxes; effects of incorporated radioisotopes on the stability of genetic materials; interrelation of root and leaf absorption of radioisotopes in herbaceous plants; uptake of radioactive wastes by lowland rice from soils contaminated by irrigation water, and decontamination of the rice; and comparison between mutation rates induced by acute and chronic gamma irradiations. (B.O.G.)
Individual canine synovial villi were used to establish short-term synovial organ cultures. These villi incorporated /sup 3/H-glucosamine into highly-polymerized /sup 3/H-hyaluronic acid (/sup 3/H-HA), which was the only /sup 3/H-glycosaminoglycan identified in the culture medium. Some /sup 3/H-HA, and larger amounts of other /sup 3/H-glycosaminoglycans, were recovered from cultured tissues. Culture medium /sup 3/H-HA content was proportional to the surface area of cultured villi. Organ cultures of nonvillous synovium were compared with villi; nonvillous cultures synthesized less /sup 3/H-HA per mm2 of their synovial intimal surface than villi. These cultures complement cell culture techniques for in vitro studies of synovial lining cell function.
The distribution of /sup 35/S-sulfate and /sup 3/H-glucosamine in the angular region of the hamster was studied by light and electron microscopic autoradiography following intraperitoneal injection of these compounds to hamsters. Exposed silver grains of /sup 35/S-sulfate were concentrated in the trabecular meshwork, sclera, and cornea, and grains of /sup 3/H-glucosamine were localized in the trabecular region. The radioactivity of both isotopes was observed in the Golgi apparatuses of the endothelial cells of the angular aqueous plexus and the trabecular meshwork. The grains were noted over the entire cytoplasm, except for the nucleus, and then were incorporated into the amorphous substance and collagen fibers in the region adjacent to the angular aqueous sinus. These results suggest that endothelial cells in the angular region synthesize and secrete the sulfated glycosaminoglycans and hyaluronic acid.
The aims of the present work were to investigate possible compatibility between sodium zirconium phosphate (NZP) and Synroc titanate phases, to prepare NZP-based waste forms by hot-pressing rather than sintering, and to investigate the incorporation in NZP of (a) Cs/Sr as simulated heat-generating nuclides; (b) simulated actinides; and (c) simulated Purex waste. The NZP samples were prepared by methods similar to those used for Synroc. The precursor NZP phase was formed from tetrabutyl zirconate Zr(OC{sub 4}H{sub 9}){sub 4}, sodium nitrate, and 85% orthophosphoric acid. Simulated waste nitrate solutions were then mixed with the liquid precursor. After stir drying of the precursor, calcination was carried out at 700{degree}C to remove nitrates and organics.
A mass transfer model has been developed to describe the rate of absorption (or desorption) of H{sub 2}S and CO{sub 2} in aqueous blends of a tertiary and a secondary or a primary amine. The model is based on penetration theory, and all significant chemical reactions are incorporated in the model. The reactions are taken to be reversible, with reactions involving only a proton transfer considered to be at equilibrium. The particular amines studied in this research were methyldiethanolamine (MDEA), a tertiary amine, and diethanolamine (DEA), a secondary amine. Key physicochemical data needed in the model, such as diffusion coefficients, kinetic rate constants, and gas solubilities, were measured. Experimental absorption rates of CO{sub 2} and H{sub 2}S were measured in a model gas-liquid contacting device and were compared with model predictions. Experiments were carried out for single amine solutions (both MDEA and DEA) and for amine blends.
A rapid combustion unit (Baird and Tatlock) incorporating a combustion chamber provided with baffle plates for complete combustion of the sample without the use of a catalyst has been assembled in a glove box for the determination of carbon and hydrogen in actinide complexes. The unit has been modified employing a movable electric furnace and a proportional temperature controller, for decomposition of the sample at desired heating rates. The set-up was standardised employing various reference materials such as benzoic acid, acetanilide, sulphanilamide and 1-chloro 2:4 dinitrobenzene and the standard deviation in the measurements evaluated. It has also been used successfully for the determination of carbon in uranium carbide and carbon and hydrogen in some uranyl-#beta#-diketone-amine N-oxide complexes and in plutonium(IV) oxalate. (auth.).
A rapid combustion unit (Baird and Tatlock) incorporating a combustion chamber provided with baffle plates for complete combustion of the sample without the use of a catalyst has been assembled in a glove box for the determination of carbon and hydrogen in actinide complexes. The unit has been modified employing a movable electric furnace and a proportional temperature controller, for decomposition of the sample at desired heating rates. The set-up was standardised employing various reference materials such as benzoic acid, acetanilide, sulphanilamide and 1-chloro 2:4 dinitrobenzene and the standard deviation in the measurements evaluated. It has also been used successfully for the determination of carbon in uranium carbide and carbon and hydrogen in some uranyl-#beta#-diketone-amine N-oxide complexes and in plutonium(IV) oxalate. (auth.).
A new procedure for preparing an 211At-labeled radiopharmaceutical is suggested. The 211At? anion forms a strong bond with the Rh3+ cation incorporated in the complex with a thiother ligand, 1,5,9,13-tetrathiacyclohexadecane-3,11-diol (16-S4-diol). The reaction conditions are optimized with 131I as astatine analog. The complexes are studied by paper electrophoresis, ion exchange, and thin-layer chromatography. The kinetics of the addition of the 131I? anion to Rh(16-S4-diol) and the dependence of the yield of the forming complex 131I-Rh(16-S4-diol) on the temperature, solution acidity, and reactant concentrations are examined. Taking into account the results obtained, the complex 211At-Rh(16-S4-diol) is prepared by adding astatide (211 At?) to equivalent amounts of RhCl3 and the tetrathioe...
Glycosaminoglycan synthesis by two subpopulations of a mouse mammary tumor cell line was compared. The two sublines express distinctly different growth characteristics in vitro and in vivo which indicate differences in growth regulation. Newly made glycosaminoglycans were recovered from the culture media, the cell surfaces, and residual cellular material. The cell population which grows more aggressively in vivo (+SA subline, a subline that grows in soft agarose) incorporated about 8 times more (/sup 14/C)glucosamine per cell into total glycosaminoglycans than did the slower-growing population (-SA subline, which does not grow in soft agarose). Appropriate control experiments indicated that the apparent difference in rates of synthesis was not due to discrepancies in glucosamine uptake. The main residual cellular molecule labeled was heparan sulfate, but the predominant molecule at the cell surface and in the culture fluid was hyaluronic acid. ...
Functionalization of carbon nanotubes is very challenging for their applications. The paper here describes a new method to functionalize multi-walled carbon nanotubes (MWCNTs) as specific affinity adsorbents. MWCNTs were acid purified and pretreated with (3-aminopropyl)-triethoxysilane (APTES) in order to introduce abundant amino groups on the surface of MWCNTs. After the conversion of amino groups to carboxyl groups by succinic acid anhydride, MWCNTs were attached to protein A or aminodextran using 1-ethyl-3,3' (dimethylamion)-propylcarbodiimide as a biofunctional crosslinker. The incorporation of aminodextran as a spacer arm noticeably increased the binding capacity of the APTES-modified MWCNTs for protein A. The application of affinity MWCNTs for purification of immunoglobulin G was then evaluated. The affinity of MWCNTs with AMD spacer exhibited a high adsorption capacity of {approx}361 {mu}g IgG/mg MWCNT (wet ...
Cell-penetrating peptides (CPPs) are useful tools for the delivery of hydrophilic bioactive molecules, such as peptides, proteins, and oligonucleotides, across the cell membrane. To realize the delivery of therapeutic macromolecules by CPPs, the CPPs are required to show resistance to protease and no cytotoxicity. In order to produce potent non-toxic and protease-resistant CPPs with high cellular uptake, we designed an amphipathic helix peptide using ?-aminoisobutyric acid (Aib, U) and named it MAP(Aib). In the MAP(Aib) molecule, five Aib residues are aligned on the hydrophobic face of the helix and five lysine (K) residues are aligned on the hydrophilic face. MAP(Aib) showed potent resistance to trypsin and pronase compared with MAP, an amphipathic helix peptide formed by usual amino acids. Fluorescein-labeled MAP(Aib) efficiently traversed the A549 cell membrane, diffusing into the cytoplasm and slightly into the nucleus without exerting any ...
Magnetic particles have become very promising materials for drug delivery. However, preparation of magnetite particles with high surface area, biocompatibility, strong magnetic response, and suitable particle size still remains a major challenge. In this report, magnetite nanocrystal clusters with high surface areas were fabricated through a solvothermal process by introducing ammonium acetate as a porogen and trisodium citrate as a surface modification agent. The porosity, which was controlled by the reactant concentration, has been investigated in detail. The surface area of the nanocrystal clusters was as high as 141?m(2) g(-1) . Ibuprofen, as a model drug, was entrapped into the magnetite carriers. The interfacial interaction between the carboxylic groups on the drug molecules and the carboxylate groups on the carriers enhanced the loading efficiency. Low cytotoxicity in MCF-7 cell and in vitro constant drug release behavior combined with the high drug loading ...
{sup 14}C-Sugar uptake and incorporation into starch by slices of developing maize (Zea mays L.) endosperm were examined and compared with sugar uptake by maize endosperm-derived suspension cultures. Rates of sucrose, fructose, and D- and L-glucose uptake by slices were similar, whereas uptake rates for these sugars differed greatly in suspension cultures. Concentration dependence of sucrose, fructose, and D-glucose uptake was biphasic (consisting of linear plus saturable components) with suspension cultures but linear with slices. These and other differences suggest that endosperm slices are freely permeable to sugars. After diffusion into the slices, sugars were metabolized and incorporated into starch. Starch synthesis, but not sugar accumulation, was greatly reduced by 2.5 millimolar p-chloromercuribenzenesulfonic acid and 0.1 millimolar carbonyl cyanide m-chlorophenylhydrazone. Starch synthesis was dependent on kernel ...
The hypothesis of genetic defects in glycosaminoglycan (GAG) regulation among patients with insulin-dependent diabetes mellitus (IDDM) and nephropathy was assessed by studies in tissue cultures of fibroblasts obtained from 7 patients with normal urinary albumin excretion, 11 patients with diabetic nephropathy, and 6 nondiabetic control subjects. The incorporation of (2H) glucosamine and (35S) sulfate into hyaluronic acid (HA), chondroitin sulfate and dermatan sulfate (CS + DS), and heparan sulfate (HS) was measured in cells, matrix, and medium and related to micrograms of tissue protein. Large interindividual variations were seen in all three groups, and the incorporation of (3H) glucosamine into HA, CS + DS, and HS and (35S) sulfate into CS + DS and HS were not significantly different between the three groups. However, the fractional incorporation of (3H)glucosamine into HS was significantly reduced in ...
Reclamation of copper mine tailings in a cost effective, successful, and sustainable manner is an ongoing area of evaluation in the arid southwest. A study was initiated in September, 1996 near Hayden, Arizona to evaluate the use of municipal biosolids for reclaiming acidic copper mine tailings (pH of 2.5 to 4.0). The main objectives of the study were to (1) define an appropriate level of biosolids application for optimum plant growth, and (2) evaluate the effects of green waste and lime amendments. The experiment was a randomized complete block design with four biosolid rates of 20, 70, 100 and 135 dry tons/acre, three amendment treatments (none, green waste, and green waste plus lime); with three replications. Non-replicated controls (no treatment, green waste only and lime only) were included for comparison. Shortly after biosolids incorporation to a depth of 10--12 inches, composite soil samples (0--12 inches) of each plot were taken. ...
The primary objective of this task was to perform a variability study of the high activity waste (HAW) acidic feed to determine the impact of feed variability on the quality of the final grout and on the mixability of the salt solution into the dry powders. The HAW acidic feeds were processed through the neutralization/pH process, targeting a final pH of 12. These fluids were then blended with the dry materials to make the final waste forms. A secondary objective was to determine if elemental substitution for cost prohibitive or toxic elements in the simulant affects the mixing response, thus providing a more economical simulant for use in full scale tests. Though not an objective, the HAW simulant used in the full scale tests was also tested and compared to the results from this task. A statistically designed test matrix was developed based on the maximum molarity inputs used to make the acidic solutions. The maximum ...
...Department of Environmental Control to ASARCO Incorporated. (B) Amended Administrative...Department of Environmental Control to ASARCO Incorporated. (C) Second Amended...Department of Environmental Control to ASARCO Incorporated. (ii) Additional...
NMR spectroscopy combined with paramagnetic relaxation agents was used to study the positioning of the 40-residue Alzheimer Amyloid {beta}-peptide A{beta}(1-40) in SDS micelles. 5-Doxyl stearic acidincorporated into the micelle or Mn{sup 2+} ions in the aqueous solvent were used to determine the position of the peptide relative to the micelle geometry. In SDS solvent, the two {alpha}-helices induced in A{beta}(1-40), comprising residues 15-24, and 29-35, respectively, are surrounded by flexible unstructured regions. NMR signals from these unstructured regions are strongly attenuated in the presence of Mn{sup 2+} showing that these regions are positioned mostly outside the micelle. The central helix (residues 15-24) is significantly affected by 5-doxyl stearic acid however somewhat less for residues 16, 20, 22 and 23. This {alpha}-helix therefore resides in the SDS headgroup region with the face with residues 16, 20, 22 and ...
Assimilation and metabolism of /sup 14/CO/sub 2/ was compared to that of (U-/sup 14/C) sucrose in young grapefruit (ca 25 mm diameter) to determine their respective roles in fruit growth. Fixation of /sup 14/CO/sub 2/ by isolated fruit tissues during 10 min in light exceeded that in dark by 2- to 30-fold depending on tissue content of chlorophyll. Greatest apparent photosynthesis occurred in outer green peel, but green juice tissues assimilated more than did adjoining inner peel tissue. In the dark, juice tissues incorporated 2.5-fold more /sup 14/CO/sub 2/ than any other tissue. Neutral sugars accounted for a smaller proportion and organic acids, a greater proportion, of the /sup 14/C-assimilates in interior peel and juice tissues. These data suggest more extensive production of organic acids from /sup 14/CO/sub 2/ in tissues isolated from the fruit interior. In contrast, little difference among tissues was evident in ...
The inhibitory activity of chicken and crocodilian ovomacroglobulins against trypsin was measured before and after their incubation with methylamine. The result for crocodilian ovomacroglobulin showed that methylamine treatment destroyed half of its activity, in unique contrast to human alpha 2-macroglobulin and chicken ovomacroglobulin for which methylamine either destroys the inhibitory activity of the former completely or does not affect that of the latter at all. Free sulfhydryl groups of chicken and crocodilian ovomacroglobulins were titrated with 5,5'-dithiobis(2-nitrobenzoic acid) before and after incubation with trypsin. Prior to the incubation with trypsin the chicken and crocodilian proteins respectively had 0 and 1 titratable sulfhydryl per molecule of Mr 720,000. After treatment with trypsin the crocodilian protein had 3.5-4 titratable sulfhydryls, whereas there were no titratable sulfhydryls in the chicken protein. After denaturation of the ...
This paper reports on the Burning Plasma Experiment (BPX) which when operating at a toroidal field of 8.1 tesla and a plasma current of 10.6 megamps, requires peak power of 1235 megawatts and total pulse energy of over 21 gigajoules. These requirements are twice and over four times the corresponding figures for the Tokamak Fusion Test Reactor (TFTR), respectively. The design of the BPX power system has evolved, along with the tokamak, over a period of several years and has included studies of several alternative approaches. The reapplication of the existing TFTR power and energy facilities has been basic to all approaches. Among the new sources of pulse power and energy that have been considered are: direct utility grid pulsing, new flywheel units, and lead-acid storage batteries. The toroidal field power requirements are the greatest of the BPX subsystems and, fortunately, are sufficiently free of dynamics to allow the consideration of all approaches. Additional ...
Conditioned medium from Sertoli cells, prepared from testes of 20-day-old rats, contains component(s) that inhibit the incorporation of (3H)-thymidine into DNA of peritubular myoid cells (PMC) and inhibit the proliferation of PMC. These components are trypsin-resistant, heat-stable compounds having a molecular weight less than 30,000. The active inhibitory components in Sertoli cell conditioned medium are inactivated by treatment with heparinase, but not by treatment with hyaluronidase or chondroitin sulfate lyases. Addition of heparin or heparan sulfate results in inhibition of DNA synthesis by PMC in a dose-dependent manner, whereas other glycosaminoglycans (GAGs) examined (hyaluronic acid, keratan sulfate, and chondroitin sulfate) have no detectable effects. Heparin and heparan sulfate are unique among GAGs tested in inhibiting the characteristic multilayer growth pattern of PMC following the attainment of confluence in serum-rich medium. On ...
Artificial bone cements (BCs) based on poly(methyl methacrylate) (PMMA) powders and methyl methacrylate (MMA) liquid monomer also present in their formulation small amounts of other substances, including a chemical initiator compound and radiopaque agents. Because inadequate mixing of the recipe components during the manufacture of the bone cement may compromise the mechanical properties of the final pieces, new techniques to incorporate the fillers into the BC and their effect upon the mechanical properties of BC pieces were investigated in the present study. PMMA powder composites were produced in situ in the reaction vessel by addition of X-ray contrasts to the reacting MMA mixture. It is shown that this can lead to much better mechanical properties of test pieces, when compared to standard bone cement formulations, because enhanced dispersion of the radiopaque agents can be achieved. Moreover, it is shown that the addition of hydroxyapatite (HA) and acrylic ...
The nuclear pore complexes (NPCs) reversibly disassemble and reassemble during mitosis. Disassembly of the NPC is accompanied by phosphorylation of many nucleoporins although the function of this is not clear. It was previously shown that in the transmembrane nucleoporin gp210 a single serine residue at position 1880 is specifically phosphorylated during mitosis. Using amino acid substitution combined with live cell imaging, time-lapse microscopy and FRAP, we investigated the role of serine 1880 in binding of gp210 to the NPC in vivo. An alanine substitution mutant (S1880A) was significantly more dynamic at the NPC compared to the wild-type protein, suggesting that serine 1880 is important for binding of gp210 to the NPC. Moreover a glutamate substitution (S1880E) closely mimicking phosphorylated serine specifically interfered with incorporation of gp210 into the NPC and compromised its post-mitotic recruitment to the nuclear envelope of ...
The sucrose derivative 6'-deoxy-6'-(2-hydroxy-4-azido)benzamidosucrose (6'-HABS) was prepared from sucrose (via 6'-deoxy-6'-aminosucrose) and 4-amino-salicylic acid. 6'-HABS is a competitive inhibitor of sucrose influx into protoplasts from developing soybean cotyledons and of sucrose binding to membranes from the bacteria P. saccharophila. The Ki for inhibition in the soybean protoplasts was 75..mu..M. 6'-Deoxy-6'-(2-hydroxy-3-/sup 125/Iodo-4-azido)benzamidosucrose was prepared by lactoperoxidase iodination of 6'-HABS. Upon photolysis in the presence of membranes from P saccharophila, label from the photoprobe is incorporated into a sucrose inducible polypeptide of mass 84 KD in SDS-PAGE. The polypeptide is protected from labeling by the inclusion of sucrose in the photolysis mixture. Photolysis conditions which lead to specific labeling of the sucrose protectable ...
A 200 ft. tall stack, consisting of a concrete chimney with an independent acid proof brick liner built in the 1950`s, serving the Separations facility at the Savannah River Site (SRS), was evaluated for the performance category 3 (PC3) level of Natural Phenomena Hazards (NPH) effects. The inelastic energy absorption capacity of the concrete chimney was considered in the evaluation of the earthquake resistance, in particular, to compute the F{sub {mu}} factor. The calculated value of F{sub {mu}} exceeded 3.0, while the seismic demand for the PC3 level, using an F{sub {mu}} value of 1.5, was found to be less than the capacity of the concrete chimney. The capacity formulation of ACI 307 was modified to incorporate the effect of an after design opening on the tension side. There are considerable uncertainties in determining the earthquake resistance of the independent brick liner. The critical liner section, located at the bottom of the breeching ...
Dynamics and metabolism of sugars translocated into the fruit region were investigated in tomato using {sup 14}C-labelled compounds. The translocation substance in tomato is thought to be sucrose, but the amount of sucrose in its fruit is very small. Therefore, the degradation of sucrose in the fruit and its translocation to the fruit was investigated. The sucrose was digested into hexoses such as glucose, fructose, etc. and the degradation rate was considerably low. In the stage of thickening growth, sucrose was more extensively converted into other substances except for sugars compared with the coloring stage. Then, {sup 14}C-labelled fructose was given through its gynophore to investigate the degree of reproduction to sucrose. The fructose level in the fruit reached the platean by 48 hrs after the addition and gradually decreased. The radioactivities were detected in sugars, organic acids and other alcohol soluble substances, etc. These results suggest that the ...
Research highlights: #-># Morphological and chemical characterization at atomic scale of porous alumina layers anodised in ordered regimes. #-># Characterization based on the use of FEG-SEM, STEM-HAADF, STEM-EELS and STEM-X-EDS. #-># Nanoscale distribution of P-, C- and S-bearing species in the pore wall. - Abstract: Ordered porous alumina layers prepared by two-step anodising in phosphoric, oxalic and sulphuric acids have been characterized at sub-nanometer scale using electron microscopy techniques. FEG-SEM and STEM-HAADF images allowed estimating the pore size, cell wall and pore wall thicknesses of the layers. Nanoanalytical characterization has been performed by STEM-EELS and STEM-X-EDS. Detailed features of the spatial distribution of anions in the pore wall of the films have been obtained. Maximum concentration of P-species occurs, approximately, at the middle of the pore wall; adjacent to the pore for C-species, whereas the distribution of ...
The present study sought a biochemical explanation for retarded brain development in the heterozygous offspring of the phenylketonuric (PKU) mother. Two rat models of simulated maternal PKU, one induced by p-chloropheylalanine and phenylalanine and the other by phenylacetate, were employed in this investigation. Maternal PKU had no influence on cerebral concentrations of DNA, protein, and cholesterol, which were normal in the 2 d old pup. However, there was a noticeable disruption of the normal ganglioside pattern and a significant reduction of sialoglycoproteins. Concomitant with a delayed drop in the gangliosides Q/sub 1b/ and D_3, was a slower rise in M_1 and D/sub 1a/. At least 66% of sialoglycoproteins located on SDS-PAGE gel chromatograms, by radioactivity incorporated in vivo from radiolabeled N-acetylmannosamine and by ("3H) sialic acid released by neuraminidase from periodate-("3H) borohydride labeled glycoproteins, have mobilites of ...
The affinity label 8-((4-bromo-2,3-dioxobutyl)thio)adenosine 5{prime}-triphosphate (8-BDB-TA-5{prime}-TP) reacts covalently with rabbit muscle pyruvate kinase, incorporating 2 mol of reagent/mol of enzyme subunit upon complete inactivation. Protection against inactivation is provided by phosphoenolpyruvate, K{sup +}, and Mn{sup 2+} and only 1 mol of reagent/mol of subunit is incorporated. The authors have now identified the resultant modified residues. After reaction with 8-BDB-TA-5{prime}-TP at pH 7.0, modified enzyme was incubated with ({sup 3}H)NaBH{sub 4} to reduce the carbonyl groups of enzyme-bound 8-BDB-TA-5{prime}-TP and to introduce a radioactive tracer into the modified residues. Following carboxymethylation and digestion with trypsin, the radioactive peptides were separated on a phenylboronate agarose column followed by reverse-phase high-performance liquid chromatography in 0.1% trifluoroacetic acid with an ...
In this observational study, we compared erythrocyte membrane fatty acids in infants consuming formula supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA) with those consuming...Full Text Available
In ozonization of polyfunctional and humic acids in icy acetic acid the whole of organic carbon can turn into a soluble form. Mono - and dicarboxylic acids of normal structure were found in the products of ozonization.
The effect of low concentrations of nalidixic acid on ribonucleic acid (RNA) synthesis in Escherichia coli was examined. It was observed that RNA synthesis in exponentially growing...Full Text Available
The effects of low concentrations (10 nm or less) of indoleacetic acid and abscisic acid on the phytochrome-mediated attachment of barley root (Hordeum vulgare L., var. Compana)...Full Text Available
Relative densities and relative massic heat capacities have been measured for aqueous solutions of Y(ClO_4)_3, Yb(ClO_4)_3, Dy(ClO_4)_3, and Sm(ClO_4)_3 at T=(288.15,298.15,313.15, and 328.15) K and p=0.1 MPa. These measurements were made in the concentration range 0.01624#<=#m/(mol#centre dot#kg"-"1)#<=#0.41822 using a Sodev 02D Vibrating Tube Densimeter and a Picker Microflow Calorimeter, respectively. To counter the potential effects of hydrolysis, aqueous solutions of the investigated salts were acidified with perchloric acid. After correcting for the presence of the acid, the measured properties were used to calculate apparent molar volumes and apparent molar heat capacities for solutions of the perchlorate salts in water. The calculated apparent molar properties were modeled at each investigated temperature using Pitzer ion interaction equations to produce estimates of apparent molar volumes and heat capacities at infinite dilution. ...
Three cDNAs, designated IIA3, IIA3v, and IIA4, coding for P450s in the CYP2A gene subfamily were isolated from a {lambda}gt11 library prepared from human hepatic mRNA. Only three nucleotide differences and a single amino acid difference, Leu{sup 160}{yields}His, were found between IIA3 and IIA3v, indicating that they are probably allelic variants. IIA4 displayed 94% amino acid similarity with IIA3 and IIA3v. The three cDNAs were inserted into vaccinia virus, and recombinant viruses were used to infect human hepatoma Hep G2 cells. Only IIA3 was able to produce an enzyme that had a reduced CO-bound spectrum with a {lambda}{sub max} at 450 nm. This expressed enzyme was able to carry out coumarin 7-hydroxylation and ethoxycoumarin O-deethylation. cDNA-expressed IIA3v and IIA4 failed to incorporate heme and were enzymatically inactive. Analysis of IIA proteins in human liver microsomes, using antibody against rat IIA2, revealed ...
Three cDNAs, designated IIA3, IIA3v, and IIA4, coding for P450s in the CYP2A gene subfamily were isolated from a #lambda#gt11 library prepared from human hepatic mRNA. Only three nucleotide differences and a single amino acid difference, Leu"1"6"0#->#His, were found between IIA3 and IIA3v, indicating that they are probably allelic variants. IIA4 displayed 94% amino acid similarity with IIA3 and IIA3v. The three cDNAs were inserted into vaccinia virus, and recombinant viruses were used to infect human hepatoma Hep G2 cells. Only IIA3 was able to produce an enzyme that had a reduced CO-bound spectrum with a #lambda#_m_a_x at 450 nm. This expressed enzyme was able to carry out coumarin 7-hydroxylation and ethoxycoumarin O-deethylation. cDNA-expressed IIA3v and IIA4 failed to incorporate heme and were enzymatically inactive. Analysis of IIA proteins in human liver microsomes, using antibody against rat IIA2, revealed two ...
The purpose of this study was to examine arachidonic acid (AA) metabolism and to characterize the type of adrenergic receptor (AR) involved in the production of the major metabolite of this fatty acid. ({sup 14}C)AA was incubated with GPT-rings and the radiolabelled products were extracted and separated by TLC method. The medium was also assayed for radiolabelled immunoreactive PG's (iPG's) and leukotrienes (LT) B4 and C4 by RIA or Enzyme immunoassay (EIA) after exposure to various AR agonists. ({sup 14}C)AA was incorporated into GPT-rings and metabolized mainly into iPGE2 and smaller amounts into PGF2{alpha}. Trace amounts of PGD2 and 6-keto-PGF1{alpha} but not LTB4 or LTC4 were detected by RIA and/or EIA. Incubation of GPT rings for 15 minutes with isoproterenol and salbutamol resulted in a significant increase of PGE2 synthesis (optimum conc: 10{sup {minus}7}, 10{sup {minus}7}M respectively). In ...
The purpose of this study was to examine arachidonic acid (AA) metabolism and to characterize the type of adrenergic receptor (AR) involved in the production of the major metabolite of this fatty acid. ["1"4C]AA was incubated with GPT-rings and the radiolabelled products were extracted and separated by TLC method. The medium was also assayed for radiolabelled immunoreactive PG's (iPG's) and leukotrienes (LT) B4 and C4 by RIA or Enzyme immunoassay (EIA) after exposure to various AR agonists. ["1"4C]AA was incorporated into GPT-rings and metabolized mainly into iPGE2 and smaller amounts into PGF2#alpha#. Trace amounts of PGD2 and 6-keto-PGF1#alpha# but not LTB4 or LTC4 were detected by RIA and/or EIA. Incubation of GPT rings for 15 minutes with isoproterenol and salbutamol resulted in a significant increase of PGE2 synthesis (optimum conc: 10"-"7, 10"-"7M respectively). In contrast, dobutamine, norepinephrine, phenylnephrine ...
Glycosaminoglycans (GAG) are believed to be important in the pathogenesis of atherosclerosis. We have previously demonstrated that areas of injured aorta that have been re-endothelialized accumulate increased amounts of lipid and GAG when compared to areas remaining de-endothelialized. We have now examined the net incorporation of labeled precursors into the individual GAG present in both re-endothelialized and de-endothelialized areas of rabbit aorta. Aortic tissue was examined at 2-3 and 10-14 weeks after a denuding injury by incubating tissue minces with (/sup 3/H)glucosamine and sodium (/sup 35/S)sulfate for 24 hr. Following incubation, the aortic GAG were isolated and assayed for uronic acid concentration and radioactivity. Results indicate that the total GAG concentration was significantly greater in the re-endothelialized as compared to de-endothelialized areas. The concentration in uninjured aorta was 9.01. The difference between the ...
A liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for the simultaneous determination of the 10 major components of Da-Cheng-Qi decoction (rhein, emodin, aloe-emodin, chrysophanol, rheochrysidin, naringin, naringenin, hesperidin, magnolol and honokiol) in dog plasma. Plasma samples were spiked with internal standard (ibuprofen), acidified with HCl and extracted twice by liquid-liquid extraction using ethyl acetate. Separation was performed on a YMC-Pack ODS-A C(18) column (5 microm, 150 mm x 4.6 mm) and a C(18) guard column (5 microm, 4.0 mm x 2.0 mm) with methanol-water (92:8, v/v) at a flow rate of 0.3 mL/min. The LC/MS system was operated under the multiple reaction monitoring mode using electrospray ionization in the negative ion mode. All analytes showed good linearity over a wide concentration range (r>0.99). The linear range of the calibration curves was 5000-19.53 ng/mL for rhein; 400-3.13 ng/mL for emodin; 800-3.13 ng/mL ...
Finely divided ash-containing coal is immersed in an aqueous solution of hydrochloric acid or citric acid, and acidic ammonium fluoride to cause the ash to react with the acid and the acidic ammonium fluoride, and the deashed coal is thereafter separated from the solution.
Using nitrogen-13 initial measurements have been made of rumen ammonia-nitrogen pool size and turnover, and rate of incorporation of ammonia into microbial protein. It is also feasible to measure the rate of incorporation of absorbed ammonia into urea and the appearance of label in saliva.
1. β-Hydroxy-β-methyl[3-14C]glutaryl-CoA is efficiently incorporated into rubber on incubation with Hevea brasiliensis latex, and the incorporation is diminished...Full Text Available
Ruthenium-106 administered to newborn rats and swine was incorporated into the epithelium of the lower small intestine and retained there for a few weeks after gavage; the stomach and small bowel of guinea pigs incorporated "1"0"6Ru but did not retain it.
The GLC analysis of carthamus tinctorius (safflower) yielded average hexane extracted oil content of 28% (25-30%); the oil contained high level of linoleic acid (74%). Monounsaturated fatty acid, oleic acid amounted 12.94%, while the saturated fatty acids like palmitic acid and stearic acid were 9.43 and 1.81%, respectively. Iodine value of linoleic acid was found to be 160:1 while its purity was 93.1%. (author)
... program incorporates the proven concepts of advanced distributed learning, modeling and simulation, and electronic digital libraries (Figure 1) to ...
... In 1982 an acousto-optic spectrum analyzer incorporated ... the OPTIMP is the optically controlled optical ... switch that changes the intensity reflectance ...
Decreased membrane rigidity is one of the characteristics of malignant cells, resulting in part from the desaturation of stearic acid into oleic acid. In this study we investigated the influence of...Full Text Available
AIM: To search the independent factors determining gastric juice acidity and to investigate the acidity of gastric juices in various benign and malignant upper gastrointestinal diseases.METHODS:...Full Text Available
Gastric acid hypersecretory states are a group of disorders characterized by basal hypersecretion of gastric acid and historically include a number of disorders associated with hypergastrinemia,...Full Text Available
Boric acid poisoning in 11 infants, occurring in the newborn nursery as a result of the accidental and inadvertent use of 2.5% boric acid in the preparation of the formulae, is reported. Five of the...Full Text Available
Uranium(VI)-salicylic acid system has been studied polarographically in perchloric acid medium. Varying concentrations of HClO/sub 4/ and salicylic acid have been used. The nature of the polarographic waves is irreversible.
A field experiment was conducted during the summer of 1988 to test the hypothesis that water deficit affects the abscisic acid (ABA) and indole acetic acid (IAA) concentrations in cotton (Gossypium...Full Text Available
The phytochrome-mediated attachment of mung bean (Phaseolus vulgaris L., var. Oklahoma 612) root tips on glass is quickly affected by indoleactic acid and abscisic acid at concentrations...Full Text Available
Dicarboxylic acids are prominent features of several diseases, including Reye's syndrome and inborn errors of mitochondrial and peroxisomal fatty acid oxidation. Moreover, dicarboxylic acids are potentially...Full Text Available
Amino acid transport was studied in membrane vesicles of the thermophilic anaerobic bacterium Clostridium fervidus. Neutral, acidic, and basic as well as aromatic amino acids were transported at 40...Full Text Available
Experiments were conducted to investigate indole-3-acetic acid (IAA) and abscisic acid (ABA) metabolism associated with postanthesis senescence of ovaries from nonpollinated muskmelon (Cucumis...Full Text Available
Statements about the dynamic processes of uptake, transport, and deposition of Ca and Mg in norway spruce and Scots pine are made in this paper. Concerning the storage of these elements it is shown that there are great differences in their functional importance in cell metabolism. There is evidence that the role of Mg in enzyme and protein metabolism is of far greater significance for the understanding of Mg-deficiency symptoms than its function as the central atom of the chlorophyll complexes. In regard to the transport and especially to the incorporation of Ca into the needles differences between species were evident, expressing the special status of pine among the gymnosperms. With increasing needle age an accumulation of Ca-oxalate crystals, which are physiologically inert, could be proved for the studied conifers. This was interpreted as a 'detoxication' from surplus Ca to hold constant the level of the physiologically active fraction. Accordingly, the low ...
One rationale proposals to increase the efficiency of PDT is to combine photo-sensitization with other treatment modalities, including modulation of arachidonic acid metabolism. In combine treatment we examined the effects of 48 h and 24 h pre-treatment of cells with 5- lipoxygenase inhibitor MK-886 prior to photoactivation of hypericin on cell cycle distribution and DNA synthesis. All parameters were examined 24 hours after hypericin activation. Pre-treatment of HT-29 with 5-lipoxygenase inhibitor MK-886 followed by PDT resulted in most significant effects on cell cycle perturbations. Administration of MK-886 alone as well as combination of low doses MK-886 with hypericin induced S phase accumulation. Increasing of MK-886 concentration induced massive changes in the cell cycle progression. Pre-treatment of HT-29 cells with MK-886 alone (15 #mu#M; - 48 h) caused accumulation of cells in S-phase (58 % in S-phase and 36 % in G_0/G_1 phase). However, after followed ...
We present the draft genome sequence and its analysis for Fusobacterium nucleatum sub spp. vincentii (FNV), and compare that genome with F. nucleatum ATCC 25586 (FN). A total of 441 FNV open reading frames (ORFs) with no orthologs in FN have been identified. Of these, 118 ORFs have no known function and are unique to FNV, whereas 323 ORFs have functional orthologs in other organisms. In addition to the excretion of butyrate, H2S and ammonia-like FN, FNV has the additional capability to excrete lactate and aminobutyrate. Unlike FN, FNV is likely to incorporate galactopyranose, galacturonate, and sialic acid into its O-antigen. It appears to transport ferrous iron by an anaerobic ferrous transporter. Genes for eukaryotic type serine/threonine kinase and phosphatase, transpeptidase E-transglycosylase Pbp1A are found in FNV but not in FN. Unique ABC transporters, cryptic phages, and three types of restriction-modification systems have been ...
As the last step of urinary acidification, the inner medullary collecting duct (IMCD) is thought to secrete protons into the tubular lumens by means of a H(+)-translocating adenosinetriphosphatase (H(+)-ATPase). However, recent studies have also shown the existence of Na(+)-H+ exchange activity in IMCD cells. Although the physiological function of the antiporter in IMCD cells is unknown, activation of Na(+)-H+ exchange in other cell-culture systems has been suggested to be closely associated with the process of cell growth. Thus presence of Na(+)-H+ exchange may relate to the growth phase of these cells. To examine intracellular pH (pHi) regulation in growing IMCD cells, we studied proton transport by Na(+)-dependent and Na(+)-independent mechanisms by microfluorimetry using the pHi-sensitive dye 2',7'-bis(carboxyethyl)-5,6-carboxyfluorescein acetoxymethyl ester (BCECF/AM). Actively growing cells, defined by (3H)thymidine incorporations, ...
Hepatic injury and regeneration of the liver are associated with activation of hepatic stellate cells (HSC). Fibroblast growth factors (FGFs) and their receptors are important regulators of repair in various tissues. HSC express FGFR3IIIc as well as FGFGR4 and different spliced FGFR1IIIc and FGFR2IIIc isoforms which differ in the presence or absence of the acid box and of the first Ig-like domain. Expression of FGF9, known to be capable to activate the HSC FGFR2/3-isoforms, was increased in HSC in liver slice cultures after exposition to carbon tetrachloride, as an acute liver injury model. FGF9 significantly stimulated 3-H thymidine incorporation of hepatocytes, but failed to induce DNA synthesis in HSC despite the fact that FGF9 induced a sustained activation of extracellular signal-related kinases (ERK) 1/2. FGF9 induced an increased phosphorylation of Tyr436 of the fibroblast growth factor receptor substrate (FRS) 2, while phosphorylation ...
Effective commercial liquid absorption technology currently applicable for CO{sub 2} capture from power plant flue gases uses a conventional chemical solvent, MEA(monoethanolamine), which was developed over 60 years ago as general non selective solvent to remove acid gases from natural gas streams. The application to CO{sub 2} capture from almost atmospheric pressure flue gases required modification of the technology on account of the oxygen content to incorporate inhibitors to resist solvent degradation and equipment corrosion, as well as upstream treatment of the flue gases to remove both SO{sub x} and NO{sub x} present. The solvent strength used by such processes is relatively low in comparison with high strength modern chemical solvents. The resultant effect is large equipment and high regeneration energy requirements which is a parasitic load on the power plant. Using current technology for CO{sub 2} capture from flue gas derived from ...
A Lurgi baseline study was requested by the DOE/GRI Operating Committee of the Joint Coal Gasification Program for the purpose of updating the economics of earlier Lurgi coal gasification plant studies for the production of substitute natural gas (SNG) based on commercially advanced technologies. The current study incorporates the recent experience with large size Lurgi plants in an effort to improve capital and operating costs of earlier plant designs. The present coal gasification study is based on a mine mouth plant producing 250 billion Btu (HHV) per day of SNG using the Lurgi dry bottom coal gasification technology. A Western subbituminous coal was designated as the plant food, obtained from the Rosebud seam at Colstrip, Montana. This study presents the detailed description of an integrated facility which utilizes coal, air, and water to produce 250 billion Btu (HHV) per day of SNG. The plant consists of coal handling and preparation, twenty-six Lurgi dry ...
A hyaluronic acid binding fraction was purified from the supernatant media of both 3T3 and murine sarcoma virus (MSV) transformed 3T3 cultures by hyaluronate and immunoaffinity chromatography. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis resolved the hyaluronate affinity-purified fraction into three major protein bands of estimated molecular weight (M/sub r,e/) 70K, 66K, and 56K which contained hyaluronate binding activity and which were termed hyaluronate binding proteins (HABP). Hyaluronate affinity chromatography combined with immunoaffinity chromatography, using antibody directed against the larger HABP, allowed a 20-fold purification of HABP. Fractions isolated from 3T3 supernatant medium also contained additional binding molecules in the molecular weight range of 20K. This material was present in vanishingly small amounts and was not detected with a silver stain or with (/sup 35/S)methionine label. The three protein species isolated by ...
Recently, in various production engineering of inorganic chemistry system, a large quantity of acids such as nitric acid and hydrocholoric acid have been used, the examples that acid and slats with high concentration are included in the sewer, treatment technique of acid-effluent in the sewer has been known as the diffusion-dialysis, acid-retardation using anion exchange resin. In this report, treatment and properties of acid-effluent recovery and effect of a coexisting slat by the diffusion-dialysis and acid retardation were compared. In the acid retardation, the concentration beyond the solution system can be recovered when the flow interval between waste acid and water was selected appropriately. In the diffusion-dialysis, it has a tendency that rate of recovery was low in the ...
The study to get some fundamental materials was carried out, aiming at the recovery of valuable components from red mud produced in the bauxite processing. Acid leaching of red mud was used to clarify the effect of leaching time, leaching temperature and acid concentration on the recovery. The used acids were hydrochloric acid, sulfuric acid and nitric acid of which concentrations were 1.45, 1.8 and 1.2mol-l; the temperature was 25, 40 and 60 centigrade; and the time was 1, 2, 4 and 8 hours. Al in red mud was leached by all acids, became the equilibrium after 10 minutes, and was independent og the temperature and the leaching rate was about 70%. When the acid concentration was raised to two time for sulfuric acid and hydrochloric acid, the leaching rate increased by 15%. Si ...
Stainless steel is pickled in pickling bath with the sulfuric acid and a mixture of hydrofluoric acid and nitric acid. Suitable equipment based on speedy and accurate chemical analysis for actual production lines has not been developed yet. The concentration of sulfuric acid can be analyzed by using the neutralization titration method. As a method of analyzing hydrofluoric acid in the mixed acid, the iron-acetylacetone complex discoloration absorbance method was adopted. For the concentration, of nitric acid, the method of subtracting the concentration of hydrofluoric acid from the total mixed acid amounts obtained by neutralization titration is adopted. Furthermore, the iron-salicylic acid complex absorbance method is adopted as a method of analyzing the iron content. By ...
Fourier-transform infrared (FTIR) spectroscopy was used to monitor amino acids, organic acids, and changes during ripening. Twelve Cheddar cheese samples were ripened for 73 days and samples were drawn periodically. Water-soluble fractions of samples were analyzed by gas chromatography (20 amino acids), liquid chromatography (three organic acids), and FTIR spectroscopy (4000-700 cm-1). Spectra were correlated with chromatographic data and ripening events and analyzed by multivariate statistics to develop prediction and classification models. Most models showed a good fit (correlation coefficient > or =0.89) and could predict the levels of amino acids and organic acids and age of the cheese in less than 20 min. Lactic acid, leucine, glutamic acid, asparagine, phenylalanine, and valine were ...
Our research in the general area of acid catalysis involves the characterization of solid acidity and the corresponding assessment of catalytic performance of acidic materials. Acid characterization studies are required to provide essential information about the type of acid site (i.e., Lewis versus Bronsted), the strength of the sites, and the mobility of molecules adsorbed on the acid sites. An accurate measure of acid strength is given by the heat of adsorption of a basic probe molecule on the acid site. A thermodynamic representation of the mobility of adsorbed species on these sites is given by the entropy of adsorption. Important techniques used in these acid site characterization studies include microcalorimetry, thermogravimetric measurements, temperature programmed desorption, infrared ...
The attenuation of gamma rays in some fatty acids, viz. formic acid (CH_2O_2), acetic acid (C_2H_4O_2), propionic acid (C_3H_6O_2), butyric acid (C_4H_8O_2), n-hexanoic acid (C_6H_1_2O_2), n-caprylic acid (C_8H_1_6O_2), lauric acid (C_1_2H_2_4O_2), myristic acid (C_1_4H_2_8O_2), palmitic acid (C_1_6H_3_2O_2), oleic acid (C_1_8H_3_4O_2) and stearic acid (C_1_8H_3_6O_2), has been measured at the photon energies 81, 356, 511, 662, 1173 and 1332 keV. Experimental values for the molar extinction coefficient, the effective atomic number and the electron density have been derived and compared with theoretical calculations. There is good agreement between experiment and theory.
Theoretical investigations of fatty acids as a phase change material (PCM) for energy storage system have been conducted in this study. The selected fatty acids were capric acid, lauric acid, myristic acid, palmitic acid and stearic acid. For the two-dimensional simulation model based on the enthalpy approach, calculations have been made for the melt fraction with conduction only. Glass, stainless steel, tin, aluminium mixed, aluminium and copper were used as heat exchanger materials in the numerical calculations. Theoretical results show that capric acid was found good compatibility with latent heat storage system. The large value of thermal conductivity of heat exchanger materials did not make significant contribution on the melt fraction. (author)
This research investigated the influence of stearic acid on the injection molding of alumina, by varying the concentration of stearic acid. The interaction between stearic acid and alumina was identified using transmission infrared spectroscopy, indicating stearic acid preferentially adsorbed onto the alumina powder surface. In addition to slightly modifying the intrinsic binder viscosity, stearic acid adsorbed onto the powder surface changed the flow behavior of the mixtures from dilatant flow to pseudoplastic flow at low temperatures. As a result, inhomogeneous distribution of binder in the injection-molded parts was minimized with increased stearic acid concentration. However, the possibility of forming bubbles in the mixtures arising from vaporization of stearic acid was enhanced. Additionally, the binder burnout temperature range was ...
Georgia Power`s primary boiler cleaning solvent in the past has been hydrochloric acid. Citric acid has recently been used on two boilers in an effort to move to a safer and more environmentally acceptable cleaning solvent. As with any change, there is a learning curve and the (new) cleaning process has to be proven with regard to process consistency and cleaning effectiveness. This paper describes our experiences with citric acid along with comparisons of past hydrochloric acid cleanings.
1. The fluorescent fatty acid probe 11-(dansylamino)undecanoic acid (DAUDA) binds with high affinity to bovine and human serum albumin (BSA and HSA) at three sites. 2. The Kd of the primary binding...Full Text Available
The influence of exogenous indole-3-acetic acid (IAA) and indole-3-butyric acid (IBA) on the internal levels of these auxins was studied during the first 4 days of adventitious root formation in cuttings...Full Text Available
A study to define the effectiveness limits of sulfamic acid and to discover other better stabilizers for Pu(III) is described. Ascorbic and isoascorbic acids, used in conjunction with sulfamic acid reduced Pu(IV) to stable Pu(III) in nitric acid. Aminoguanidine sulfate also retarded the oxidation of Pu(III) but did not reduce Pu(IV). (J.R.D.)
Four low activation alloy classes, two austenitic and two ferritic, have been incorporated into the MOTA-1B experiment in the FFTF reactor to provide an early assessment of the suitability of such alloys for reactor service.
It is an object of the present invention to provide an improved installation having a pressurized fluid circuit incorporating fluidic brakes for restricting fluid flow through a breach of the installation. (author).
As medical schools incorporate medical informatics into their curriculum the problems of implementation arise. Because there are no standards regarding a medical informatics curriculum, medical schools...Full Text Available
ObjectiveTo describe the development and assessment of monographs as an assignment to incorporate evidence-based medicine (EBM) and pharmacoeconomic principles into a third-year...Full Text Available
When autotrophically growing cultures of Chlorella are treated with levulinic acid, δ-aminolevulinic acid is excreted into the medium, providing a direct demonstration of α-aminolevulinic...Full Text Available
Bacterial hydroxy fatty acids and alpha-hydroxy fatty acids have been demonstrated in complex lipid extracts of subgingival plaque and gingival tissue. However, little is known about the relationship...Full Text Available
IntroductionAcute lung injury (ALI) may arise both after sepsis and non-septic inflammatory conditions and is often associated with the release of fatty acids, including oleic acid...Full Text Available
The mixture of lauric acid and capric acid is a potential latent heat storage material. However, its eutectic melting temperature is quite high for low-temperature thermal energy storage. Addition of naphthalene is proposed. The ternary system lauric acid-capric acid-naphthalene has been investigated by differential scanning calorimetry (DSC), visual polythermal and chromatography of gases. The phase diagram is of an incongruent eutectic type. The eutectic mixture contains 18.4mol% lauric acid, 63.1mol% capric acid and 18.5mol% naphthalene and melts at 13.3{sup o}C. The peritectic mixture contains 32.4mol% lauric acid, 48.2mol% capric acid and 19.4mol% naphthalene and peritectic temperature of 16.2{sup o}C. The incongruent compound was analysed to be CH{sub 3}(CH{sub 2}){sub 10}COOH.CH{sub 3}(CH{sub 2}){sub 8}COOH. The ...
The pharmacokinetics of fusidic acid and 3-ketofusidic acid were investigated in cholestatic and noncholestatic patients after intravenous administration of single and multiple doses of 500 mg of sodium...Full Text Available
The concentration of some organic acids in the atmosphere was determined using a wet effluent diffusion denuder-aerosol collector coupled with Ion Chromatography. Three organic acids and four inorganic anions were identified and quantified in the air sample, taken from the backyard of PSI. (author)
A process for the recovery of nitrilotriacetic acid values from solutions containing polyvalent metal complexes of nitrilotriacetic and the decomposition products thereof is described, the process being characterized by the addition to such solutions of sufficient strong acid to dissociate the complex under conditions to precipitate the nitrilotriacetic acid.
The present invention relates to a method of acidizing a subterranean formation or well bore employing an acidic solution containing a corrosion inhibitor composition comprising an inhibiting effective amount of an acetylenic alcohol, a quaternary ammonium compound, an aromatic hydrocarbon and an antimony compound.
Salicylic acid (SA) is an important component of systemic-acquired resistance in plants. It is synthesized from benzoic acid (BA) as part of the phenylpropanoid pathway. Benzaldehyde (BD), a potential...Full Text Available
Synthetic polypeptide antigens of L amino acids, although bearing repeating sequences, are thymus-dependent (L-TD), whereas the same polymers composed of D amino acids are thymus-independent (D-TI),...Full Text Available
The heat storage material consists of a mixture of oleic and stearic acids in which stearic acid is present to the extent of 30 percent to 90 percent by weight. In addition to this binary system, the invention is also directed to a ternary system in which diphenyl ether is present along with the stearic and oleic acids.
Little is known about the metabolic origin of petroselinic acid (18:1 delta 6cis), the principal fatty acid of the seed oil of most Umbelliferae, Araliaceae, and Garryaceae species. To examine the possibility...Full Text Available
Results of field applications of boric acid in the secondary coolant circuits of seven PWR units for the purpose of reducing the rate of corrosion denting are reported. Based on available data at the power plants considered in this study, it was not possible to support or refute the benefit of using boric acid secondary water treatment.
Sialic acids are structurally unique nine-carbon keto sugars occupying the interface between the host and commensal or pathogenic microorganisms. An important function of host sialic acid is to regulate...Full Text Available
Ammonium sulfate is produced from spent sulfuric acid from the production of alcohols. Certain mineral and organic impurities exist in the sulfuric acid that impair the quality of the ammonium sulfate. A detailed method for the chemical analysis for the impurities is presented.
Amino acid transport was studied in membranes of the peptidolytic, thermophilic, anaerobic bacterium Clostridium fervidus. Uptake of the negatively charged amino acid L-glutamate, the neutral amino...Full Text Available
Methods of acidizing a subterranean well formation, acidizing compositions, and sequestering additives for preventing the precipitation of metal compounds in the formation are described. Use of the methods and chemicals described should lead to improved formation permeability as compared to use of previous methods and chemicals. 12 claims.
A novel acidizing process is used to increase the permeability of carbonate rock cores in the laboratory and to remove drilling fluid damage from cores and wafers. Field results show the benefits of the technology as applied both to injector and producer wells.
The interaction of long-chain fatty acids with cells is important for their uptake and metabolism, as well as their involvement in signalling processes. The majority of long-chain fatty acids circulating...Full Text Available
To determine if medium and long chain fatty acids can be appropriately metabolized by species that normally produce 16 and 18 carbon fatty acids, homogenates of developing Cuphea wrightii, Carthamus...Full Text Available
The research has involved the characterization of catalyst acidity, [sup 2]D NMR studies of Bronsted acid sites, and kinetic, calorimetric, and spectroscopic studies of methylamine synthesis and related reactions over acid catalysts. Approach of this work was to explore quantitative correlations between factors that control the generation, type, strength, and catalytic properties of acid sites on zeolite catalysts. Microcalorimetry, thermogravimetric analysis, IR spectroscopy, and NMR spectroscopy have provided information about the nature and strength of acid sites in zeolites. This was vital in understanding the catalytic cycles involved in methylamine synthesis and related reactions over zeolite catalysts.
The rate of corrosion of hardened cement paste in solutions of nitric, hydrochloric, sulfuric, acetic and formic acids was compared. Corrosion in solutions of acetic and nitric acids with different concentrations was studied in more detail. The results made it possible to obtain the relationships expressing the influence of concentration and the time of action of acid solutions on the depth of corrosion. The rates of corrosion in nitric acid solutions during the first 3 years were about 2 to 4 times that in acetic acid solutions, depending on the concentration.
Intensive measurements of organic acids, inorganic acids, aldehydes and peroxyacetyl nitrate (PAN) in urban air were carried out at a Southern California smog receptor site, Glendora, CA, August 12-22, 1986. The objective of this project was to augment the data base regarding organic acids in urban air and to assess their role with emphasis on ambient levels, diurnal variations, phase distribution, emissions, in-situ formation and removal. The relative abundance of organic acids and inorganic acids was determined for the first time from simultaneous measurements carried out during this study.
The objective of the present study is to reveal thermal characteristic of microcapsulated lauric acid slurry in circular pipe. Test were performed with microcapsulated lauric acid slurry in a heating test section with a constant heat flux boundary condition. Local Nusselt number and the effective thermal capacity were measured. As the size of microcapsulated lauric acid were increased, local Nusselt number of microcapsulated lauric acid slurry were increased. The effective thermal capacity of microcapsulated lauric acid slurry was 0.5 times than it of water.
A method, based on anion exchange chromatography, is presented for the isolation of "1"3"9Ce after production by a proton-induced nuclear reaction on a thick praseodymium target. After bombardment the target is dissolved in nitric acid and "1"3"9Ce oxidised to the Ce(IV) oxidation state with bromic acid. "1"3"9Ce is then separated form the praseodymium by anion exchange chromatography on a Ag MP-1 resin column in a nitric acid - bromic acid mixture. "1"3"9Ce is sorbed onto the resin column and praseodymium eluted with the acid mixture. The bromic acid is washed out of the column with nitric acid and "1"3"9Ce finally eluted with dilute nitric acid containing sulphur dioxide.
... The phenol and cresylic acid stream is flashed in a thin film evaporator over a concentrated sulfuric acid mixture to remove pyridine type substances ...
Poly(ethylene terephthalate) (PET) powder from waste bottles was degraded at atmospheric pressure in 7--13 M nitric acid at 70--100 C for 72 h, to clarify the mechanism of a feed stock recycling process. Terephthalic acid (TPA) and ethylene glycol (EG) were produced by the acid-catalyzed heterogeneous hydrolysis of PET in nitric acid, and the resulting EG was simultaneously oxidized to oxalic acid. The kinetics of the hydrolysis of PET in nitric acid could be explained by a modified shrinking core model of chemical reaction control, in which the effective surface area is proportional to the degree of unreacted PET, affected by the deposition of the product TPA. The apparent rate constant was inversely proportional to particle size and to the concentration of the nitric acid. The activation energy of the reaction was 101.3 kJ/mol.
Erythrocytes serve as reservoirs for cis- and trans-epoxyeicosatrienoic acids (EETs). Incubation of rat red blood cells (RBCs) with cis- and...Full Text Available
Objective and sourcesWe reviewed the epidemiologic literature for PFOA.Data synthesisPerfluorooctanoic acid (PFOA) does not occur naturally but is...Full Text Available
Pathways of salicylic acid (SA) biosynthesis and metabolism in tobacco have been recently identified. SA, an endogenous regulator of disease resistance, is a product of phenylpropanoid metabolism formed...Full Text Available
Methods were developed for the separation of radioactively labeled carbohydrate components of proteoglycans by isocratic ion-moderated partition HPLC. Neutral sugars were separated after hydrolysis in trifluoroacetic acid with baseline separation between glucose, xylose, galactose, fucose, and mannose. N-Acetylneuraminic acid, N-acetylated hexosamines, glucose, galactose, and xylitol were likewise well separated from each other under isocratic elution conditions. Glucuronic acid, iduronic acid, and their lactones were separated after hydrolysis in formic acid and sulfuric acid. Glucosamine, galactosamine, galactosaminitol, and glucosaminitol were separated by HPLC on a cation exchanger with neutral buffer after hydrolysis in hydrochloric acid. THe separation techniques also proved useful in fractionation of exoglycosidase digests of O- and ...
Acidosis in the gastrointestinal tract can be both a physiological and pathological condition. While gastric acid serves digestion and protection from pathogens, pathological acidosis is associated...Full Text Available
...Systems by IPEX Enfield electrofusion acid waste systems give you the proven corrosion resistance of polypropylene, along with our patented, state-of-the-art electrofusion system....
Contrary to the electronic excitation induced phenomena of desorption and sputtering, we observed incorporation of oxygen in a thin Fe film during its irradiation with swift heavy ions. It is observed that the adsorbed oxygen diffuses in to the Fe film. The incorporation of oxygen and its diffusion in the bulk of the film is a manifestation of extremely large electronic energy deposition by the incident ions. It is shown that the experimentally observed high diffusivity of oxygen in Fe during irradiation is due to the existence of transient melt phase of Fe.
Reactive Magnetron Sputtering is a complex process and huge efforts are made addressing the understanding of its fundamental phenomena and the simulation of the deposition process by e.g. Particle in Cell/Monte Carlo (PIC/MC). One of the most uncertain parameters in this reactive sputtering process is the incorporation coefficient of the reactive gas in the growing layer, i.e. the real-time sticking coefficient during deposition. In this work, mass spectrometry is used to deliver more insights on this complex matter. Earlier, a method was developed to determine the incorporation coefficient of the reactive gas molecules in the growing metal film, using mass spectrometry combined with thin film analysis techniques (electron probe microanalysis and x-ray photoelectron spectroscopy). This method delivers a global, realistic incorporation coefficient which can be used in models for the reactive sputtering process. In this work, ...
A new separation process of saturated fatty acids (lauric acid-myristic acid) using crystallization from an aqueous ethanol solution has been examined. There were two vessels in this separation process: an extraction vessel and a crystallization vessel. The fatty acids in the aqueous phase were first extracted from their organic phase (melt) in the extraction vessel. The fatty acids in the aqueous phase were continuously introduced to the crystallization vessel, and then the fatty acids were crystallized there. The crystals of the fatty acids were collected continuously above the aqueous phase in the crystallization vessel. In this process, the yield and the purity of the crystals over time were measured, and it was found that the purity of lauric acid increased unsteadily up to 0.98 mole fraction of lauric ...
Inorganic acids are commonly used for surface cleaning and finishing of metals. The acids become unuseable due to contamination with metals or diluted and weakened. Diffusion dialysis has become a way to recover the useable acid and allow separation of the metals for recovery and sale to refineries. This technique is made possible by the use of membranes that are strong enough to withstand low ph and have long service life.
The thermodynamic characteristics of adsorption of sulfur-containing amino acids and their derivatives on the surface of graphitized thermal carbon black were calculated by the molecular statistical method. The parameters of the atom-atom potential function of intermolecular interaction between the S atom in amino acids and the graphite C atom were determined. It was shown that an intramolecular H-bond influenced the adsorption of amino acids on the surface of graphitized thermal carbon black.
The thermodynamic characteristics of adsorption of sulfur-containing amino acids and their derivatives on the surface of graphitized thermal carbon black were calculated by the molecular statistical method. The parameters of the atom-atom potential function of intermolecular interaction between the S atom in amino acids and the graphite C atom were determined. It was shown that an intramolecular H-bond influenced the adsorption of amino acids on the surface of graphitized thermal carbon black.
A hydrocarbon composition having a major portion of a hydrocarbon preferably a lubricating oil such as mineral oil and at least a friction-reducing amount usually 0.01 to 10 weight percent of an amine or amine derivative of a hydrocarbon-soluble polymerized fatty acid e.g. a dimeramine derived from a dicarboxylic acid containing at least 12 carbon atoms such as 9(10)-carboxy stearic acid has improved antifriction and flue economy properties.
Peroxisome proliferator activated receptor-{gamma} (PPAR{gamma}) regulates metabolic homeostasis and adipocyte differentiation, and it is activated by oxidized and nitrated fatty acids. Here we report the crystal structure of the PPAR{gamma} ligand binding domain bound to nitrated linoleic acid, a potent endogenous ligand of PPAR{gamma}. Structural and functional studies of receptor-ligand interactions reveal the molecular basis of PPAR{gamma} discrimination of various naturally occurring fatty acid derivatives.
Thermodynamic analysis of dissolution processes of tungsten minerals in citric acid solutions in the absence and in the presence of hydrochloric acid has been carried out by means of calculation of Gibbs energy of the chemical reactions. Kinetic characteristics, such as specific dissolution rates and activation energies, are determined. It is established that the dissolution reactions studied take place in kinetic region. A possibility of scheelite selective dissolution in the presence of other tungsten minerals is shown.
Details of a series of reactions for the production of ethylene glycol using a catalyst of Nafion solid perfluorosulfonic acid resin was detailed. The reactions included the carbonylation of formaldehyde and esterification and then hydrogenation of the product of the carbonylation, glycolic acid. Other preparations included in the work included methyl glycolate, acetylglycolic acid, methyl acetylglycolate, and methyl methoxyacetate.
This patent describes a catalyst comprising: (a) a non-zeolitic inorganic oxide matrix, and (b) an ultrastable Y-type crystalline zeolite, the ziolite having been pretreated by contacting the zeolite with a phosphorus compound selected from the group consisting of phosphoric acid, phosphorous acid, a salt of phosphoric acid, a salt of phosphorous acid, and mixtures thereof for a time sufficient to composite an effective amount of phosphorus with the zeolite.
A method for the chemical modification of the initial structure of humic acids by acylation with indole-3-acetic acid chloride was developed to increase the biological activity of preparations based on peat and lignite humic acids. The plant growth stimulating effect and the antibacterial activity of the synthesized humic preparations were studied.
In this study, the influences of cultivar on the phenolic composition and antioxidant properties of 15 different basil varieties was determined. Cultivar had a statistically significant effect on total phenolic levels (p<0.001) and anthocyanin concentrations (p<0.001). Analysis of individual phenolic acid levels by high-performance liquid chromatography showed substantial variations in the phenolic acid profiles among cultivars. Rosmarinic (p<0.001), chicoric (p=0.002) and caffeic (p=0.001) acid concentrations were affected by cultivar, although caftaric acid levels (p=0.083) were not. Nine of the cultivars in this study contained chicoric acid in higher concentrations than rosmarinic acid. These are the first basil cultivars that have been identified in which rosmarinic acid is not the do...
Quantitative determination of Broensted acid site concentrations in calcined H-mordenite and H-ZSM-5 by means of conductometric titration and infrared spectroscopy reveals that the concentration of Broensted acid sites present is lower than would be expected on the basis of the aluminum content. This discrepancy is attributed to dealumination and dehydroxylation processes occurring during calcination. A model is proposed according to which the degree of these processes strongly depends on the concentration of vicinal aluminum T sites in the zeolite: Broensted acid sites associated with these T sites are lost, and the remaining Broensted acidity is related to the concentration of the (remaining) isolated aluminum T sites. This model quantitatively correlates the experimentally determined concentration of Broensted acid sites with the concentration of isolated aluminum T sites. 33 ...
A process is described for the recovery of uranium values from phosphoric acid utilizing an alkyl pyrophosphoric acid (Appa) primary extractant. After extracting the uranium from the phosphoric acid, the appa extractant is deactivated by heating and the uranium values stripped into a phosphoric acid strip solution containing ferric ion as a salting agent. The uranium values may then be re-extracted directly from this stripping solution without adjustment of its concentration into a dialkyl phosphoric acid trialkyl phosphine oxide synergistic extractant from which a relatively pure yellow cake is precipitated. A new procedure for preparing the requisite appa primary extractants is also disclosed.
We tried to apply a quartz crystal as a sensor by using the resonant frequency and the resistance properties of quartz crystals. Four kinds of fatty acids that have the same head groups were coated on the surfaces of the quartz crystals, and the shift of the resonant frequency and the resistance were observed based on the lengths of the tail groups. Myristic acid (C{sub 14}), palmitic acid (C{sub 16}), stearic acid (C{sub 18}), and arachidic acid (C{sub 20}) were deposited on the surfaces of quartz crystals by using the Langmuir-Blodgett (LB) method. As a result, the resonant frequency change was more sensitive to high molecular-weight fatty acids than to low molecular-weight ones. We also observed the effect of temperature on stearic acid LB films, and the response properties of quartz crystals coated with stearic-acid ...
The ruthenium decontamination factor in Purex process falls quickly with recycles of TBP. So it is necessary to change the chemical states of RuNO complexes in order to improve DF_R_u in the uranium purification cycle. The retention of RuNO complexes in TBP-kerosenelaurohydroxamic acid is observed to be quite large in our previous work. Therefore, water-soluble short chain hydroxamic acid is used as complexing agent to decrease the distribution coefficient of Ru. Hydroxamic acid can transform RuNO complexes into in-extractable species by TBP-kerosene in certain conditions. The result of cascade experiment indicates that the ruthenium decontamination can be increased by a factor of 40-50. Acidity has more influence on the effect of pretreatment. The higher acidity is, the worse the effect will be. The pretreatment is first carried out in low acidic solution, then ...
Ethylen and, recently, butadiene can be epoxidized directly with oxygen and for the epoxidation of propylene, the use of heterogeneous transition metals and organic peroxides (Halcon-Process) is the major player. But, beside from those notable exceptions, all other epoxidations, including large ones like the epoxidation of plant oils as PVC-stabilizers (about 200.000 t/year), are carried out with peroxy acids. Because mcpba is far to expensive for most applications, short chain peracids like peracetic acid are used. Being much less stable than mcpba and thus risky handled in large amounts and high concentrations, these peroxy acids were preferably prepared in-situ. However, conventional in-situ formation of peracids has the serious drawback, that a strong acid is necessary to catalyze peroxy acid formation from the carboxylic acid and hydrogen peroxide. The ...
This study was undertaken to determine if a combined treatment (marinating in natural plant extracts or vacuum) with irradiation could have a synergistic effect, in order to prevent the lipid oxidation resulting in the development of undesirable flavours. The fresh chicken legs were irradiated at 0,3 and 5 kGy. The fatty acids composition of lipids was identified using gas liquid chromatography. The effect of irradiation treatment combined with a pre-treatment on the fatty acids composition was followed. The day after irradiation, ten panallists were asked to evaluate, using the instruction scaling, the overall appearance, the odor, the flavor and the overall acceptability of the samples. The major fatty acids identified in lipids were oleic acid, palmitic acid, palmitoleic acid and stearic acid. Pre-treatments have a significant effect on ...
The effects of pH on the calcium phosphate phase, of Tris and of amino acids, such as aspartic acid, glutamic acid, and serine on hydroxyapatite formation and morphology, were studied in double diffusion experiments. In this system, hydroxyapatite was only formed when the pH was around 7.4 or higher for the duration of the reaction. A decrease in pH resulted in the transformation of hydroxyapatite to octacalcium phosphate. Amino acids and Tris or the buffering capacity of Tris have an effect on the morphology of the synthetic hydroxyapatite. The presence of the additive results in spheres consisting of needles, blades or plates depending on the reaction system. PMID:12175941
In the prevention of atmospheric pollution by sulfur dioxide emissions from acid absorbers in contact process sulfuric acid plants in which the unconverted SO/sub 2/ is accumulated by adsorption in a zeolite adsorbent bed and desorbed back into the acid production system, it is found that ambient moist air, after partial dehydration in an acid scrubber is suitably used both to cool down and hot purge desorb the zeolite beds. In addition the pure water derived from the ambient air is advantageously used in the acid-making system.
This paper obtains the acidity spectra of modernites and SVK-zeolites from the heats of adsorption of NH/sub 3/ at 300 C and compares the catalytic activity of these zeolites with the cracking of n-octane and the isomerization of o-xylene. It is shown that the calculation of the specific catalytic activity of centers of different strengths by the method of regional rates allows one to predict the activity of the zeolites from the acidity spectra. It follows from the calculation that only the centers of Bronsted acidity are active towards cracking but that the centers of Lewis acidity are also active towards isomerization.
["1"4C]Cadaverine was applied to leaves of Lupinus polyphyllus, L. albus, L. angustifolius, L. perennis, L. mutabilis, L. pubescens, and L. hartwegii and it was preferentially incorporated into lupanine. In Lupinus arboreus sparteine was the main labelled alkaloid, in L. hispanicus it was lupanine. A pulse chase experiment with L. angustifolius and L. arboreus showed that the incorporation of cadaverine into lupanine and sparteine was transient with a maximum between 8 and 20 h. Only leaflets and chlorophyllous petioles showed active alkaloid biosynthesis, whereas no incorporation of cadaverine into lupanine was observed in roots. Using in vitro organ cultures of Lupinus polyphyllus, L. succulentus, L. subcarnosus, Cytisus scoparius and Laburnum anagyroides the inactivity of roots was confirmed. Therefore, the green aerial parts are the major site of alkaloid biosynthesis in lupins and in other legumes. (orig.).
X-ray photoelectron spectroscopy measurements indicate that the Ce{sup 3+} like fraction in {gamma}-Al{sub 2}O{sub 3} supported CeO{sub 2} can be decreased by the incorporation of La{sup 3+}. If La{sup 3+} is incorporated into the {gamma}-Al{sub 2}O{sub 3} before CeO{sub 2} is added, a higher CeO{sub 2} dispersion and a greater range of reversible reducibility of the CeO{sub 2} may also be obtained. These changes offer potential for improvement in the oxygen storage capacity provided by CeO{sub 2} in three-way catalysts. The actual effect of La{sup 3+} incorporation on the activity and durability of a Pt catalyst is assessed by a combination of temperature programmed reduction and flow reactor measurements.
This study presents a full cost approach to determine the levelized cost of energy (LCOE) of 14 electricity generation technologies. It encompasses costs incurred at all stages of the fuel cycle, including those that are traditionally omitted from economic evaluations of generation technologies. Incorporating these 'externalities' increases the likelihood of developing the most economical and sustainable power resource from a societal perspective. The following externalities are included in this analysis: damage from air pollution, energy security, transmission and distribution costs, and other environmental impacts. Incorporating externalities has a large impact on the LCOE and the relative attractiveness of electricity generation options. Results indicate that clean and efficient generation technologies are the most attractive when all options are examined using a full cost, levelized approach. (author)
The ultrafine fibers based on the composites of polyethylene terephthalate (PET) and a series of fatty acids, lauric acid (LA), myristic acid (MA), palmitic acid (PA), and stearic acid (SA), were prepared successfully via electrospinning as form-stable phase change materials (PCMs). The morphology and thermal properties of the composite fibers were studied by field emission scanning electron microscopy (FE-SEM) and differential scanning calorimetry (DSC), respectively. It was found that the average fiber diameter increased generally with the content of fatty acid (LA) in the LA/PET composite fibers. The fibers with the low mass ratio maintained cylindrical shape with smooth surface while the quality became worse when the mass ratio is too high (more than 100/100). Moreover, the latent heat of the composite fibers increased with the increase of LA content and the ...
An extruder used by kneading stearic acid (St acid) into it for the production of polystyrene for injection molding was studied. Most disadvantageous of kneading methods, melt-feed method, was applied because this method enables the utilization of existing facilities. St acid is discolored when the temperature surpasses 270{sup 0}C in nitrogen atmosphere, and the contact with metals intensifies the discoloring. The discoloring is more intensified by the contact with nitriding steel than with stainless steel. Residence time is 85 seconds, and even the contact with nitriding steel does not discolor ST acid when the temperature is lower than 270{sup 0}C. In the melt-feed method, when the die is in a bad shape, it brings about dead space at the tip of the die and St acid holds up there. When the kneading is in bad condition (St acid and polymer are hard to mix ...
In this study, two different humic acids extracted from England and China peat soil, as well as three purified products extracted from commercially available humic acids [Fluka (Fluka, Neu-Ulm, Germany, Alfa (Alfa Aesar, Ward Hill, USA) and Aldrich (Aldrich-Chemical Co, Gillingham-Dorset)] were obtained respectively with the modified IHSS (International humic substances society) procedure. The chemical and structural information of these humic acids were characterized by some techniques, such as elemental analysis, ultraviolet-visible spectroscopy (UV-Vis), Fourier transform infrared spectroscopy (FTIR) and electropotential titration. UV-Vis spectra, infrared spectra, values for elemental composition and the contents of carboxyls, phenolic hydroxyls and total acidities of these humic acids were acquired. It is indicated that all these humic acids are different ...
In-situ decontamination technologies were evaluated for their ability to: (1) reduce equipment contamination levels to allow either free release of the equipment or land disposal, (2) minimize residues generated by decontamination, and (3) generate residues that are compatible with existing disposal technologies. Six decontamination processes were selected. tested and compared to 4M nitric acid, a traditional decontamination agent: fluoroboric acid (HBF{sub 4}), nitric plus hydrofluoric acid, alkaline persulfate followed by citric acid plus oxalic acid, silver(II) plus sodium persulfate plus nitric acid, oxalic acid plus hydrogen peroxide plus hydrofluoric acid, and electropolishing using nitric acid electrolyte. The effectiveness of these solutions was tested using prepared 304 stainless steel ...
Corrosion in drilling and well stimulation is described in relation to acid corrosion inhibition, acid inhibitors, acetylenic inhibitors, synergistic blends, metallurgy, wellbore tubulars, coiled tubing, and high alloy tubular materials. Acidizing is a procedure for stimulating oil and gas wells. Factors that have an important influence on the reaction rate and the way in which acid reacts with rock include temperature, acid concentration, acid volume, injection velocity, acid viscosity, and fluid loss properties of the formation. The cost of drill pipe failures are $1 per fot of hole drilled, which is a significant fraction of the drilling cost. Steps in a test procedure are listed, as well as factors which determine the extent of acid corrosion in a given situation including acid type and strength, ...
Lipase catalyzed esterification reactions between lactic acid and several fatty acids have been studied. Difficulties arise in esterifying lactic acid because of the potential for this substance to act both as an acyl donor and as a nucleophile. These difficulties were minimized via strategies which greatly increased the yield of the desired ester. Use of the companion fatty acid in excess with respect to lactic acid in an apolar solvent (n-hexane) in which the lactic is not completely dissolved has been employed to minimize the potential for lactic acid to act as an acyl donor in a self-polymerization reaction.Beneficial and sinergistic effects of both silica gel and molecular sieves on conversion to the desired product are described. However, careful control of the amount of molecular sieves used is required. This fact is a consequence of two opposing effects ...
The aims of investigation were to follow the Sr transport in the food chain from the flora to the fauna and humans, and its dependence on the geological origin og the plant site, industrial emissions, the age and site of plants, the part of plant used for nutrition and the strontium content in the drinking water, to determine the Sr intake of humans with the help of the duplicate method, and to estimate the apparent absorption rate and balance of strontium depending on of the form of diet (mixed or ovolactovegetarian), sex, season, age, region (geological origin of the living space) and method of intake measurement (duplicate or basket method). Strontium, an ultra trace element widespread in the earth's crust, is not essential and only mildly toxic for plants, animals and man according to current knowledge. The biological essentiality of Sr has not been investigated yet. Amoeba species living in sea water use Sr for the formation of their skeleton instead of Ca. There have been no Sr ...
Incorporating Environmentally Conscious Materials Selection in CAD System Narito Shibaike, Matsushita Electric, Japan ...Ikeda, Matsushita Erectric H.Ishida, INAX Y.Ishikawa, Japan Techno-Economics ...Tsuchiya*, Matsushita Electric Com- ponents Y.Tsuchiya*, Society of Japanese Value
Uracil appears in DNA as a result of cytosine deamination and by incorporation from the dUTP pool. As potentially mutagenic and deleterious for cell regulation, uracil must be removed from DNA....Full Text Available
This short paper (abstract) describes the characteristics and performances of prototypes of ultra-thin lithium micro-batteries (thickness < 0.2 mm) which can be incorporated into microelectronic circuits. (J.S.)
ObjectiveTo refine the CT prediction of emphysema by comparing histology and CT for specific regions of lung. To incorporate both regional lung density measured by CT and cluster...Full Text Available
Chest compression-only (CC-only) is now incorporated in the Norwegian protocol for dispatch guided CPR (cardiopulmonary resuscitation) in cardiac arrest of presumed cardiac aetiology.We present...Full Text Available
Natural abundance 13C solid-state nuclear magnetic resonance spectroscopy was used to investigate the effect of the incorporation of cholesterol on the dynamics of dimyristoylphosphatidylcholine (DMPC)...Full Text Available
Adaptive radiation therapy (ART) is the incorporation of daily images in the radiotherapy treatment process so that the treatment plan can be evaluated and modified to maximize the amount of radiation...Full Text Available
Middle segment pancreatectomy (MSP) is a new operation where the advantages of parenchymal preservation are counterbalanced by a high postoperative complication rate and unease among surgeons with adopting...Full Text Available
The article reviews the Rothschild First Interim Report on the future of the British Coal Industry and British Coal Corporation. The report incorporates work undertaken by the Joint Working Groups set up with British Coal. The article points out various errors in the report and criticizes its conclusions.
ObjectiveTo develop consistent variable names and a common database structure for the data elements in the International Spinal Cord Injury (SCI) Data Sets.Full Text Available
Activation-induced cytidine deaminase (AID) protein initiates Ig gene mutation by deaminating cytosines, converting them into uracils. Excision of AID-induced uracils by uracil-N-glycosylase...Full Text Available
User acceptance of a computer system depends on a number of factors, including broad social and professional concerns regarding the system's impact on the work environment. This observation is especially...Full Text Available
Electronic personal health records (ePHRs) can potentially maximize access and coordination of health information and improve patient/clinician collaboration, patient self-management, and health outcomes....Full Text Available
Mist eliminators for flue gas desulphurisation units remove liquid droplets entrained in the flue gas leaving the SO/sub 2/-absorber vessels. The commercial designs currently available are described.
Random forest (RF) analysis of genetic data does not require specification of the mode of inheritance, and provides measures of variable importance that incorporate interaction effects. In this paper...Full Text Available
Although humans vary in their response to chemicals, comprehensive measures of susceptibility have generally not been incorporated into human risk assessment. The U.S. EPA dose-response-based risk assessments...Full Text Available
Recently, the Tri-Party Agreement (TPA) among the State of Washington Department of Ecology, U.S. Department of Energy (DOE) and the US Environmental Protection Agency (EPA) for the cleanup of the Hanford Site was renegotiated. The revised agreement specifies vitrification as the encapsulation technology for low level waste (LLW). A demonstration, testing, and evaluation program underway at Westinghouse Hanford Company to identify the best overall melter-system technology available for vitrification of Hanford Site LLW to meet the TPA milestones. Phase I is a {open_quotes}proof of principle{close_quotes} test to demonstrate that a melter system can process a simulated highly alkaline, high nitrate/nitrite content aqueous LLW feed into a glass product of consistent quality. Seven melter vendors were selected for the Phase I evaluation: joule-heated melters from GTS Duratek, Incorporated (GDI); Envitco, Incorporated (EVI); Penberthy Electomelt, ...
The formation of the nicotinamide adenine dinucleotide phosphate-dependent formate dehydrogenase in Clostridium thermoaceticum is stimulated by the presence of molybdate and selenite...Full Text Available
In response to reports that the contamination of food can occur during the on-farm primary phase of food production, we report data that describes a possible cost-effective intervention measure. The...Full Text Available
The results of clinical trials conducted in Europe and North America have been incorporated into treatment strategies for breast cancer in Japan. Despite the use of similar treatment regimens, why has...Full Text Available
BackgroundThis is a preliminary report of an ongoing prospective bimodality lung cancer surveillance trial for high‐risk patients. Bimodality surveillance incorporates autofluorescence...Full Text Available
Manganous chloride and Congo red incorporated into blotting paper discs have been used to differentiate gonococci from meningococci. The new technique is simple and reliable; the materials for the test...Full Text Available
Incorporation of clinical decision support (CDS) capabilities is required to realize the greatest benefits from computerized provider order entry (CPOE) systems. Discussions at a conference on CDS in...Full Text Available
...analysis for all of the stacks except the ASARCO stacks. (i) Incorporation by reference...1985 (except for materials pertaining to ASARCO), and January 28, 1986 (except for meterials pertaining to ASARCO and Appendix A). (19) On...
...specifications of ASTM Grade 1 or Grade 2 fuel oils in ASTM Method D396-04, Standard Specification for Fuel Oils (incorporated by reference, see...ASTM Grade 4, Grade 5, or Grade 6 fuel oils in ASTM Method D396-04,...
The role of natural enemies in the regulation of populations is one of the major questions facing population ecologists. Simplification have led to two theoretical ways of incorporating the role of natural enemies in single ecological models: diffusion models and patch-type models. The predictions of the models are different because of the way variability is incorporated. Three equations are presented for diffusion models and one for patch models. Since the two types of models apply at different combinations of spatial and temporal scales, the right model(s) to choose for a particular study requires careful assessment. A continuing dialogue between experimentalists and theoreticians will lead to a better understanding of natural systems such as those that occur in biological control.
The extraction of Am(III) and Eu(III) has been investigated using mixtures of synthesized aromatic dithiophosphinic acids (R_2PSSH) and tributylphosphate (TBP), trioctylphosphine oxide (TOPO) or tributylphosphine oxide (TBPO) in toluene from nitric acid (0.01-1.5 mol l"-"1). There was no detectable extraction when R_2PSSHs were used alone as extractants for either Am(III) or Eu(III) (D_A_m_,_E_u<10"-"4) under the experimental conditions used in this study. High separation factors (D_A_m/D_E_u>20) with D_A_m>1 were achieved in the nitric acid range 0.1-1 moll"-"1 by means of a synergistic mixture of bischlorodithiophosphinic acid with TBP, TOPO or TBPO. (orig.)
This work describes a three-step pre-treatment route for processing spent commercial Ni Mo/Al_2O_3 catalysts. Extraction of soluble coke with n-hexane and/or leaching of foulant elements with oxalic acid were performed before burning insoluble coke under air. Oxidized catalysts were leached with 9 mol L"-"1 sulfuric acid. Iron was the only foulant element partially leached by oxalic acid. The amount of insoluble matter in sulfuric acid was drastically reduced when iron and/or soluble coke were previously removed. Losses of active phase metals (Ni, Mo) during leaching with oxalic acid were compensated by the increase of their recovery in the sulfuric acid leachate. (author)
The mixture of 65 mol% capric acid and 35 mol% lauric acid (C-L acid) is a potential latent heat storage material. However, its melting temperature of 18.0 {sup o}C is quite high for low-temperature thermal energy storage. Addition of pentadecane, with a melting point of 9.9 {sup o}C, is proposed. The thermal characteristics of the combination of the C-L acid with pentadecane (CL:P) in different volume ratio are investigated employing the DSC analysis. The actual thermal performance of each CL:P combination is further determined from their radial and axial temperature distribution employing a fabricated thermal storage capsule. The 90:10 CL:P combination manifests an improvement in the melting characteristic of the C-L acid.(author)
Background/Aims Serum free fatty acid (FFA) composition and abnormal fatty acid metabolism have been implicated in the pathogenesis of nonalcoholic steatohepatitis (NASH). Therefore, we determined if the serum FFA composition can provide accurate diagnosis of NASH. Methods We compared fasting serum FFA compositions in 20 patients with simple steatosis to those in 77 patients with NASH, including 65 patients with early-stage NASH. Results By univariate analysis, the proportions of serum free myristic acid (P?=?0.002) and palmitoleic acid (P?=?0.033) and the stearoyl CoA desaturase (SCD)-1 index (P?=?0.047) were significantly elevated in NASH patients in comparison to patients with simple steatosis. Only the serum free myristic acid proportion was significantly elevated in the early-stage NA...
Isopropyl chloroacetate has been synthesized by esterification of chloroacetic acid and isopropanol, using lanthanum dodecyl sulfate (LDDS) as the catalyst. Various factors that affected the esterification have been investigated, such as reaction time, different water-carrying agent and the amount of catalyst. Under the condition of 1.2/1 molar ratio of isopropanol to chloroacetic acid, 1.0% catalyst (molar percent of chloroacetic acid), 2.5 h reaction time, 5 mL cyclohexane as water-carrying agent and reflux temperature, the esterification conversion of isopropyl chloroacetate reaches 98.3%. The catalytic activity of LDDS is almost equal to that of a Bronsted acid. LDDS, as one kind of water-tolerant Lewis acid, is an excellent catalyst compared to the traditional Lewis acid. (author)
Field-grown snap bean plants were treated with simulated acidic rain applied either alone or in combination with ambient rain and the effects on growth and yield were determined. In plots where ambient rain was excluded, a retractable canopy was activated to shield the crop. Four levels of acidity at pH values of 5.0, 4.2, 3.4 and 2.6 were applied in four replicate treatments and the experiment was conducted in two successive years (1981 and 1982). In plots that received only simulated rain, yield was not adversely affected by acidic rain; in 1981, a positive linear relationship was present between acidity of simulated rain and yield, but in 1981, no effect was found. In contrast, in plots that received both simulated and ambient rain, a negative linear relationship between acidity in simulated rain and yield was observed in both years.
Using the infrared spectroscopy method, we have studied the effect of thermal dehydration (under vacuum and in air) and treatment with water vapor on the acid centers of very high silicon zeolites of the ZSM type. We have shown that dehydration under vacuum and in air completely and irreversibly removes the OH groups at 1120/sup 0/K, while treatment with water vapor removes these groups at 770/sup 0/K. The Lewis acid centers of dehydrated zeolites (represented by two types of centers) are more heat-stable than the Bronsted acid centers, but the vapor treatment at 1020/sup 0/K leads to the disappearance of the Lewis acid centers. In this work, we discuss the reasons for destruction of the acid centers of the zeolites under different treatment conditions.
Photoelectron resonance capture ionization aerosol mass spectrometry (PERCI-AMS) has been applied to the analysis of proxies for marine aerosols with and without ozone; proxies used were mixed oleic acid-amino acid particles. The mechanism of ion formation for serine (104 m/z), glutamic acid (146 m/z), and phenylalanine (164 m/z) was dissociative electron attachment. This corresponds to loss of the hydrogen atom only, allowing for straightforward identification of the free amino acids. No ozonolysis products for the free amino acids were observed, even at high concentrations of ozone (500 ppm for 19 s). The direct detection of a novel gas-phase hydrated anion, [serine + H2O-H]-, is described. These preliminary results suggest that PERCI-AMS may provide an effective, simple and direct onlin...
The study reports the identification of different organic acids that are formed during the pyrohydrolysis of mixed carbide of uranium and plutonium using ion chromatography (IC). The identification of organic acids present in the pyrohydrolysis distillate is required to carry out interference free analysis of Cl and F. The study describes three stage isocratic separations with NaOH eluents having concentrations 2 mM, 10 mM and 50 mM respectively in order to separate and identify both aliphatic and aromatic acids. The present investigation identified formic, acetic, propionic, butyric, tartaric and oxalic acids in the distillate, however, aromatic acids could not be identified. (author)
Mung bean seedlings inoculated with Enterobacter asburiae PSI3, a gluconic acid-producing rhizosphere isolate, enhanced plant growth in the presence of phytotoxic levels of Cd2+ in gnotobiotic pot experiments as compared to the uninoculated Cd-treated plants. Addition of organic acids to Cd-stressed seedlings promoted root elongation. Hematoxylin competition assays showed that organic acids could displace Cd2+ from the Cd2+: hematoxylin complex in the same order of effectiveness as was found for restoration of root net elongation viz. oxalate?>?malate?>?succinate while gluconate was effective at higher concentrations. Root associated Cd2+, assessed by hematoxylin staining of roots was found to be reduced when roots were treated with organic acid. Cd stress increased antioxidant enzymes suc...
The hemagglutinin (HA) glycoprotein of influenza virus performs two critical roles during infection: it binds virus to cell surface sialic acids, and under mildly acidic conditions it induces fusion...Full Text Available
Abstract:- This study was undertaken to investigate the antimicrobial effect of organic acids against-Escherichia coli-O157:H7,-Salmonella-Typhimurium, and-Listeria monocytogenes-on whole red organic apples and lettuce. Several studies have been conducted to evaluate organic acids as sanitizers. However, no studies have compared antimicrobial effects of various organic acids on organic fresh produce, including evaluation of color changes of produce. Apples and lettuce were inoculated with a cocktail of 3 strains each of 3 foodborne pathogens provided above and treated with 1% and 2% organic acids (propionic, acetic, lactic, malic, and citric acid) for 0, 0.5, 1, 5, and 10 min. With increasing treatment time and acid concentration, organic acid treatments showed significant reduction compar...
We have investigated the transport of tritiated indole-3-acetic acid (IAA) in intact, red light-grown maize (Zea mays) coleoptiles during gravitropic induction and the subsequent development...Full Text Available
Toxicity and potential carcinogenicity studies of boric acid were investigated in mice to verify in a second rodent species that this was a noncarcinogenic chemical. Earlier chronic studies in rats...Full Text Available
By isomorphous replacement of silicon by phosphorus the authors have synthesized crystalline aluminosilicophosphates with structures of the zeolites type A and faujasite. They determine the adsorption capacity of specimens treated at 575-1275/sup 0/K. They show that the thermal stability and acid resistance of aluminosilicophosphates depend on the quantity of phosphorus in their structure.
The purpose of this study is to determine the thermal reliability of stearic acid, palmitic acid, myristic acid and lauric acid as latent heat energy storage materials with respect to various numbers of thermal cycles. The fatty acids, as phase change materials (PCMs), of industrial grade (purity between 90% and 97%) were subjected to accelerated thermal cycle tests. The differential scanning calorimetry (DSC) analysis technique was applied to the PCMs after 0, 120, 560, 850 and 1200 melt/freeze cycles in order to measure the melting temperatures and the latent heats of fusion of the PCMs. The DSC results indicated that the change in melting temperature for the PCMs was in the range of 0.07-7.87 {sup o}C, and the change in latent heat of fusion was -1.0% to -27.7%, except for stearic acid between 560 and 1200 melt/freeze cycles. However, the decrease in the ...
The purpose of this study is to determine the thermal reliability of stearic acid, palmitic acid, myristic acid and lauric acid as latent heat energy storage materials with respect to various numbers of thermal cycles. The fatty acids, as phase change materials (PCMs), of industrial grade (purity between 90% and 97%) were subjected to accelerated thermal cycle tests. The differential scanning calorimetry (DSC) analysis technique was applied to the PCMs after 0, 120, 560, 850 and 1200 melt/freeze cycles in order to measure the melting temperatures and the latent heats of fusion of the PCMs. The DSC results indicated that the change in melting temperature for the PCMs was in the range of 0.07-7.87 deg. C, and the change in latent heat of fusion was -1.0% to -27.7%, except for stearic acid between 560 and 1200 melt/freeze cycles. However, the decrease in the latent ...
We have previously reported the construction and characterization of an autonomously replicating plasmid in Trypanosoma brucei. In this plasmid the procyclic acidic repetitive protein (PARP) gene promoter...Full Text Available
Deuterated lipoxygenase and cyclooxygenase derivatives of eicosatetraenoic acid (arachidonic acid) and their metabolites are indispensable tools for organic trace analysis, biomedical studies, and mechanistic investigations on the corresponding endogenous (unlabelled) eicosanoids. Methods for the preparation of deuterated eicosanoids are reviewed.
The objective of this research was to determine the role of acidic ribosomal protein (ARP) phosphorylation in translation. Ribosomes (Rbs) from germinated maize (Zea mays L.) axes had...Full Text Available
1. The uptake and esterification to trigylceride of oleic acid in micellar form was studied in rat intestine in vitro. Sacs of the upper half of the everted intestine taken from bile...Full Text Available
Fatty acid biomarker analysis coupled with gas chromatography-isotope ratio mass spectrometry was used to confirm the presence of methanotrophic and thiotrophic bacterial endosymbionts in the tissues...Full Text Available
The pharmacological effects of a series of fatty acid-choline esters have been studied on the isolated rabbit heart, the isolated guinea-pig ileum and the rat stomach. The effect changed with increasing...Full Text Available
Amino acid transport in membrane vesicles of Bacillus stearothermophilus was studied. A relatively high concentration of sodium ions is needed for uptake of L-alanine (Kt = 1.0 mM) and L-leucine (Kt...Full Text Available
Summary of recent advances (abstract)Nucleic acid-based nanotechnology has always been perceived as novel, but has begun to move from theoretical demonstrations to practical applications....Full Text Available
Serum protein and lipid concentrations as well as the serum protein binding of propranolol, diazepam and phenytoin were measured in normal weight and obese volunteers. Concentrations of alpha 1-acid...Full Text Available
Phosphatidic acid (PA) is postulated to have both structural and signaling functions during membrane dynamics in animal cells. In this study, we show that before a critical time period during rhabdomere...Full Text Available
Radionuclide X-ray fluorescence analysis was used for the determination of iron, calcium, potassium, copper, manganese and zinc in waste water from the production process of citric acid.
Radionuclide X-ray fluorescence analysis was used for the determination of iron, calcium, potassium, copper, manganese and zinc in waste water from the production process of citric acid. (author).
Some of most used indicators in marine ecology are nucleic acid-derived indices. They can be divided by target levels in three groups: 1) at the organism level as ecophysiologic indicators, indicators...Full Text Available
Minoxidil induces hair growth in male pattern baldness and prolongs the anagen phase. All-trans retinoic acid (ATRA) has been reported to act synergistically with minoxidil in vivo:...Full Text Available
The ultraviolet photoelectron spectra of benzoic acid and 20 of its derivatives are presented. The low-energy regions of these spectra are deconvoluted and assigned using chemical substitution effects. 5 figures, 3 tables.
Mycolic acids are key cell wall components for the survival, pathogenicity, and antibiotic resistance of the human tubercle bacillus. Although it was thought that Mycobacterium tuberculosis...Full Text Available
Evidence is presented that phorbic acid is formed in the latex producing cell system, rather than in photosynthetic or chlorophyll-free tissues of Euphorbia resinifera Berg. When a...Full Text Available
ObjectiveThe primary objective of this study was to assess whether pentagastrin-induced panic symptoms are associated with release of free fatty acids (FFAs) in a manner that could...Full Text Available
Some strains of Bradyrhizobium japonicum have the ability to catabolize indole-3-acetic acid (IAA). Examination of this catabolism in strain 110 by in vivo experiments has revealed an enzymatic activity...Full Text Available
Methylosulfonomonas methylovora M2 is an unusual gram-negative methylotrophic bacterium that can grow on methanesulfonic acid (MSA) as the sole source of carbon and energy. Oxidation...Full Text Available
When 2,2-dimethyl 3-(2'-naphthyl 6'-hydroxy) pentanoic acid, an artificial estrogen of the allenolic acid group, was added to an exponential-phase growth culture of Neurospora crassa (in Horowitz medium),...Full Text Available
Method for inhibiting the formation of foulants on petrochemical equipment which involves adding to the petrochemical, during processing, a composition comprising a thiodipropionate and either a dialkyl acid phosphate ester or a dialkyl acid phosphite ester.
In this work, coals of various ranks were dissolved in an acid melange. With the use of IR spectroscopy, it was found that the mechanism of coal dissolution consists in the grafting of polar groups to the peripheral benzene rings of graphite-like systems.
In the presence of electrochemical energy, several branched-chain neutral and acidic amino acids were found to accumulate in membrane vesicles of Bacillus stearothermophilus. The membrane vesicles contained...Full Text Available
Leucoplasts were isolated from the endosperm of developing castor (Ricinis communis) endosperm using a discontinuous Percoll gradient. The rate of fatty acid synthesis was highest...Full Text Available
An interactive system for computer analysis of nucleic acid and protein sequences has been developed for the Los Alamos DNA Sequence Database. It provides a convenient way to search or verify various...Full Text Available
Evidence is presented for a distinctive type of hippocampal synaptic modification [previously described for a molluscan gamma-aminobutyric acid (GABA) synapse after paired pre- and postsynaptic excitation]:...Full Text Available
BackgroundLead poisoning affects many organs in the body. Lead inhibits δ-aminolevulinic acid dehydratase (ALAD), an enzyme with two co-dominantly expressed alleles, ALAD1...Full Text Available
The corrosion behavior of Ta, Ti, and Zr in inorganic acids, bases, chlorides and miscellaneous salts, waters and gases, and organic acids and miscellaneous organic chemicals is summarized. (W.L.H)
The main function of white adipose tissue is to store nutrient energy in the form of triglycerides. The mechanism by which free fatty acids (FFA) move into and out of the adipocyte has not been resolved....Full Text Available
The inhibitory effects of indole-3-acetic acid (IAA) and 1-aminocyclopropane-1-carboxylic acid (ACC) on elongation growth of pea (Pisum sativum L.) seedling roots were investigated...Full Text Available
We characterized the biosynthesis of indole-3-acetic acid by the mycoherbicide Colletotrichum gloeosporioides f. sp. aeschynomene. Auxin production was tryptophan dependent....Full Text Available
The concentration of indoleacetic acid (IAA) in plant tissues is regulated, in part, by its rate of decarboxylation. However, the commonly used in vitro assays for IAA oxidase may not...Full Text Available
The hyaluronic acid capsule of Streptococcus uberis has been implicated in conferring resistance to phagocytosis by bovine neutrophils. Construction of a bank of random insertion mutants...Full Text Available
The comparative analysis of plant hormones was undertaken on a 1-naphthaleneacetic acid tolerant mutant and normal tobacco (Nicotiana tabacum cv Xanthi) plantlets. The mutant plantlet...Full Text Available
Hereditary hypouricemia may result from mutations in the renal tubular uric acid transporter URAT1. Whether mutation of other uric acid transporters produces a similar phenotype is unknown. We studied...Full Text Available
We describe a non-isotopic, semi-automated method for large-scale multiplex analysis of nucleic acid sequences, using the cystic fibrosis transmembrane regulator (CFTR) gene as an example. Products...Full Text Available
Data from exposure of experimental animals and human subjects to sulfuric acid presents a consistent picture of its toxicology. Effects on airway resistance in asthmatic subjects were well predicted...Full Text Available
Air pollution measurements were conducted over a 1-year period in 24 North American communities participating in a respiratory health study. Ozone, particle strong acidity, sulfate, and mass (PM10 and...Full Text Available
The changes in conjugated indole-3-acetic acid (IAA) levels compared to the levels of free IAA have been analyzed during the development of bean (Phaseolus vulgaris L.) seed using quantitative...Full Text Available
Effects of MgCl2 and free fatty acids (FFA) on galactolipid:galactolipid galactosyltransferase (GGGT) and UDP-galactose: 1,2-diacylglycerol galactosyltransferase (UDGT) in chloroplast envelope...Full Text Available
A monensin-sensitive ruminal peptostreptococcus was able to grow rapidly (growth rate of 0.5/h) on an enzymatic hydrolysate of casein, but less than 23% of the amino acid nitrogen was ever utilized....Full Text Available
Geometric (HOMA) and magnetic (NICS) indices of aromaticity were estimated for aromatic rings of amino acids and nucleobases. Cartesian coordinates were taken directly either from PDB files deposited...Full Text Available
BackgroundDiurnal fluctuation of bile acid (BA) concentrations in the enterohepatic system of mammals has been known for a long time. Recently, BAs have been recognized as signaling...Full Text Available
A stain of 0.1% toluidine blue in a 1.0% aqueous solution of triethylene glycol followed by decolorization with acid-alcohol resulted in mycobacteria retaining the stain (violet), whereas non-acid-fast...Full Text Available
Retinoic acid inducible gene I (RIG-I) is a pattern recognition receptor (PRR) responsible for detection of nucleic acids from pathogens in the cytoplasm of infected cells and induction of type I interferon...Full Text Available
Attention has shifted from the treatment of colorectal cancer (CRC) to chemoprevention using aspirin and folic acid as agents capable of preventing the onset of colon cancer. However, no sensitive...Full Text Available
Cited are the results of physico-chemical studies and industrial tests of a copolymer of methacrylic acid and diethylammonium salt, used for limiting the influx of stratum waters into a well.
A liquid chromatography/tandem mass spectrometric (LC/MS/MS) assay was developed for the quantitative determination of salirasib (S-trans, trans-farnesylthiosalicylic acid,...Full Text Available
The desorption of uranium from the granular titanium-activated carbon composite adsorbent (concentration of uranium: 25.5 mg/l-Ad), which adsorbed uranium from natural sea water, was examined by the column process with acidic eluent at room temperature. The column operation was able to be carried out without destruction of the granular adsorbent by the generation of the carbon dioxide, and free from disturbance of the eluent flow by precipitate of calcium sulfate dihydrate with sulfuric acid eluent. The amount of acid consumption by the adsorbent was 0.87 eq/l-Ad. The alkaline earth metals were eluted in the range of elution volume below 2l/l-Ad, whereas uranium, iron, and titanium were eluted above 2l/l-Ad. Therefore, uranium was separable from the alkaline earth metals which were adsorbed in the most quantity in the adsorbent. In the range of elution volume 2 to 12l/l-Ad, the percentage of desorbed uranium and the ...
The three-dimensional structure of the human adenovirus-2 proteinase complexed with its 11 amino acid cofactor, pVIc, was determined at 2.6 A resolution by X-ray crystallographic analysis. The fold...Full Text Available
Ripening of `Tydeman's Early' apples (Malus sylvestris L.) assessed by the occurrence of the respiratory climacteric was delayed by succinic acid 2,2-dimethyl hydrazide (B-9) but not...Full Text Available
Conjugated linoleic acid (CLA) has been the subject of extensive investigation regarding its possible benefits on a variety of human diseases. In some animal studies, CLA has been shown to have a beneficial...Full Text Available
A nucleic acid extraction system that can handle small numbers of specimens with a short test turnaround time and short hands-on time is desirable for emergent testing. We performed a comparative validation...Full Text Available
This paper presents a series of structural modifications of soybean oils for lubricant. The reaction was monitored and products were confirmed by NMR and FTIR. The structural modification is carried out in four stages, (1) synthesis of soybean oil isooctyl ester from soybean oil; (2) synthesis of epoxy-soybean oil isooctyl ester from soybean oil isooctyl ester; (3) synthesis of hydroxylated products from epoxy soybean oil isooctyl ester with fatty acid; (4) esterification of the hydroxylated product with anhydride. Rheological behaviour of the products was measured. Pour points of the products (3) were observed as low as -24 C (lauric acid) and -15 C (isooctanoic acid) respectively. When the hydroxyl groups in the products were esterified with and acid anhydride, the pour points were became higher, which were -21 C (lauric acid) and -6 C (isooctanoic acid) ...
Partial digestion of polygalacturonic acid with polygalacturonase isolated from Rhizopus stolonifer produces a mixture of α-1,4-d-galacturonide oligomers which act...Full Text Available
The concentration of free indoleacetic acid (IAA) is high in cotton (Gossypium hirsutum L.) fruiting forms before anthesis, but is low at and for a few days after anthesis. Amide-linked...Full Text Available
Zinc modulates the activity of glutamic acid decarboxylase, the rate limiting enzyme in the synthesis of gamma-aminobutyric acid (GABA), which is a major inhibitory neurotransmitter. Low cerebrospinal...Full Text Available
Behavioral responses to labellar stimulation with 19 L-amino acids were predicted on the basis of electrophysiological responses of largest labellar hairs. With the exceptions alanine, aspartic...Full Text Available
The digestion of water-extracted bark of Terminalia alata nepalensis, T. arjuna, and T. bellerica with 20% H/sub 2/SO/sub 4/ at 100 degrees resulted in the isolation of oxalic acid in 12-21% yield. The technique is not complicated and requires simple equipment.
An assay to measure the rate of enzymatic formation of 3-methylindole (3MI) from indoleacetic acid (IAA) in Lactobacillus sp. strain 11201 was developed. The reaction mixture contained 50 micrograms...Full Text Available
We used tryptophan auxotrophs of the dicot Arabidopsis thaliana (wall cress) to determine whether tryptophan has the capacity to serve as a precursor to the auxin, indole-3-acetic acid (IAA). Quantitative...Full Text Available
Anionic peroxidase from tomato (Lycopersicon esculentum) fruit oxidized indoleacetic acid (IAA) slowly in the presence of Mn2+ and dichlorophenol in acetate buffers. The...Full Text Available
Amino acids labelled with dimethylaminoazobenzenesulphonyl chloride can be separated by reversed-phase high-pressure liquid chromatography and detected in the visible region (436 nm). All 19 naturally...Full Text Available
This patent describes a delayed acrylamide containing polymer crosslinker having stability in an aqueous solution at high temperatures. It comprises: a combination of an aldehyde and a salicylic acid derivative selected from salicylamide and acetysalicylic acid.
The aim of this work was to study acute alterations of the enterohepatic recirculation (EHR) of bile acids 3 days after an 8-Gy radiation exposure in vivo in the rat by a washout technique. Using this technique in association with HPLC analysis, the EHR of the major individual bile acids was determined in control and irradiated animals. Ex vivo ileal taurocholate absorption was also studied in Ussing chambers. Major hepatic enzyme activities involved in bile acid synthesis were also measured. Measurements of bile acid intestinal content and intestinal absorption efficiency calculation from washout showed reduced intestinal absorption with significant differences from one bile acid to another: absorption of taurocholate and tauromuricholate was decreased, whereas absorption of the more hydrophobic taurochenodeoxycholate was increased, suggesting that intestinal passive diffusion was ...
The flacca tomato (Lycopersicon esculentum) mutant displays a wilty phenotype as a result of abscisic acid (ABA) deficiency. The Mo cofactor (MoCo)-containing aldehyde...Full Text Available
Interfacial tension at the aqueous solution of di-2-ethylhexylphosphoric acid or its copper salts/water solutions has been measured by the drop volume method.
Besides ethanol, acetic acid is produced in naturally fermenting sweet resources and is a significant environmental stress for fruit-breeding Drosophila populations and species. Although not related...Full Text Available
Realization of Pharmacological Tests, Development of the Specifications and Technical Documentation and Registration in the Russian Federation of Medical Products as Soluble Tablets of Acetylsalicylic Acid/Calcium Carbonate in Two Dosages Intended for use as Medical Products Smoothing, Febrifugal and Antiaggregation Action and Development of Technology of Tableting the Above-Stated Preparations
Low concentrations of sugars altered the sensitivity of seed germination to inhibition by exogenous abscisic acid (ABA). Germination of wild-type and ABA-insensitive (abi) Arabidopsis...Full Text Available
4-methylumbelliferone (4-MU) is a hyaluronic acid (HA) synthesis inhibitor with anticancer properties; the mechanism of its anticancer effects is unknown. We evaluated the effects of 4-MU on...Full Text Available
1. An acid ninhydrin reagent was found to react specifically in forming a pink product (Emax. 560mμ) with cysteine. 2. The method was highly sensitive for the determination...Full Text Available
We show that the expression of an indole-3-acetic acid (IAA)-modified protein from bean seed, IAP1, is correlated to the developmental period of rapid growth during seed development. Moreover, this...Full Text Available
The thermodynamics of protonation and europium(III) complex formation with substituted methane diphosphonic acids have been reported recently. These ligands form strong complexes with europium in moderately acidic solutions ((H{sup +}) {ge} 0.1 M), conditions not conducive to complexation by most carboxylate and aminopolycarboxylate ligands. A correlation of log {beta} vs pK{sub a} values for phosphonate and carboxylate ligands is used to explore the effect of ligand structure on complex stability. 5 refs., 1 fig.
The solvent extraction of europium(III) into solutions of thenoyltrifluoroacetone and benzoic acid in cyclohexane, carbon tetrachloride, benzene, chloroform, pentachloroethane, and tetrachloroethane has been measured at 25/sup 0/ C. It has been found that the extracted species involve two types of adducts, EuA/sub 3/HB and EuA/sub 3/ . 2HB where A denotes the TTA anion and HB the benzoic acid monomer. The magnitude of the adduct formation constants in different solvents has been correlated with the dimerization constants of benzoic acid in the solvents. 2 figures, 2 tables.
Makeup water is distilled internally in an amine gas treating unit by adding it to the reclaimer used to process a slipstream of lean amine from the stripper.
The production of oil by retorting shale and other hydrocarbonaceous and lignocellulosic solid materials is facilitated by retorting in the presence of steam and acetic acid.
Zeolite Y is the active component of most commercial cracking catalysts. Interaction of H[sub 3]PO[sub 4] with extraframework aluminum of ultra-stable zeolite (USY) leads to the formation of different types of aluminum phosphates, while there is no indication of the formation of SAPO zeotype structures. The total acidity of USY slightly decreases upon the H[sub 3]PO[sub 4] treatment, while the maximum in the distribution of acid strength is shifted to milder acidities. Dealumination of the zeolite and creation of POH sites associated with AIPO[sub 4] are responsible for the modifications observed. 37 refs., 8 figs., 3 tabs.
Acid fluids in geothermal reservoirs are rare. Their occurrence in geothermal systems associated with recent volcanism (Tatun Sumikawa, Miravalles) probably indicates that the geotherml reservoir fluid was derived from volcanic fluid incompletely neutralized by reaction with feldspars and micas. Superheated steam containing HCl (Larderello, The Geysers) forms acid where it condenses or mixes with liquid at moderate temperatures (325 deg. C). Cryptoacidity occurs at Los Humeros where HCl acidity is formed and neutralized without reaching the surface. (author). 28 refs, 9 figs, 2 tabs.
Using low-temperature adsorbed dihydrogen and carbon monoxide as molecular probes, the dehydroxylation of the hydrogen forms of the zeolites Y, and ZSM-5 has been studied. The high stability of the high-silica zeolites to dealumination and their difference from faujasites has been established as being due not only to the strength of their Broensted acid sites but also to the nature of their Lewis acid sites. The chemical properties of the Lewis acid sites and their possible role in catalytic reactions are discussed.
A fuel composition comprising a liquid hydrocarbon fuel and a detergent amount of the product of reaction between a polyamine and a stearic acid is described.
We investigated the effects of additives to the etching solution of 1 M hydrochloric acid on the electrochemical etching behavior for aluminum electrolytic capacitors, using scanning and transmission electron microscopy, and AC impedance spectroscopy. For the addition of 1 M sulfuric acid or 5% ethylene glycol to the hydrochloric acid solution, the distribution of etch tunnels was more uniform with high density of etch pits compared with that without addition. The highest specific surface area was obtained from the electrolyte with 5% ethylene glycol additive. The correlation of internal morphologies of etched foils with impedance parameters was interpreted by impedance techniques.
The authors investigated the influence of tartaric acid, which possesses complex-forming properties. In order to establish the optimum system of possible refinement of tellurium, the authors study the kinetics of both the cathodic and the anodic processes. The investigation of processes of discharging-ionization of tellurium from nitric acid electrolytes in the presence of tartrate ions showed the possibility of preparing a nitric-tartaric acid electrolyte which can be used for commercial purposes and from which a high-purity raffinate was obtained from technical tellurium.
Nitrogens, Sulfurs, Isotopes, and Hydrocarbons Gases Elements Ions and Inorganic Acids Organic Compounds Co-eluting Organics Hopanes, Cholestanes, and Sterols Pesticides,...
The presence of an amino acid other than aspartic acid at position 57 of the HLA-DQ beta chain (non-Asp-57) is highly associated with susceptibility to insulin-dependent diabetes mellitus (IDDM), whereas...Full Text Available
Degradation of cellulosics or starch in alkaline solution produces mostly organic acids which are monocarboxylic in nature. Seven of the organic acids have been identified as formic, acetic, glycolic, lactic, 2-hydroxybutyric, 2-hydroxyisobutyric and 2-hydroxyvaleric acids. In total, their yields amount to 41-46% of starting material weight.
Azobenzene dyes are effective inhibitors for austenitic 304 L and 316 L stainless steel corrosion in high acidic medium up to 7N. A good efficiency is obtained from weight loss and electrochemical Rsub(p) measurements in hydrochloric acid, while no inhibition is observed in sulfuric solutions. Transformation from the primarily azobenzene to other compounds give rise to enhanced protection of steel samples, and probable structures of the inhibiting species are proposed in view of our results.
Azobenzene dyes are effective inhibitors for austenitic 304 L and 316 L stainless steel corrosion in high acidic medium up to 7N. A good efficiency is obtained from weight loss and electrochemical Rsub(p) measurements in hydrochloric acid, while no inhibition is observed in sulfuric solutions. Transformation from the primarily azobenzene to other compounds give rise to enhanced protection of steel samples, and probable structures of the inhibiting species are proposed in view of our results.
Gas contaminated with at least one noxious component, such as SO/sub 2/, HF or NOx, is scrubbed with a clear, calcium-containing, initially-basic washing liquid which also comprises the anion of a strong inorganic acid, that of a polybasic carboxylic acid and, optionally, that of a monobasic carboxylic acid. Apparatus is provided for scrubbing the gas, oxidizing produced calcium bisulfite to calcium sulfate, separating out and removing solids, and recirculating clarified liquid for scrubbing contaminated gas.
In vitro rooting response and indole-3-acetic acid (IAA) levels were examined in two genetically related dwarfing apple (Malus pumila Mill) rootstocks. M.26 and M.9...Full Text Available
2,4-Dichlorophenoxyacetic acid (2,4-D) promotes the accumulation of tryptophan-derived indole-3-acetic acid (IAA) in carrot cell cultures during callus proliferation by a biosynthetic pathway that is...Full Text Available
Mutual influence of phosphorus and carbon on the tendency to integranular corrosion (IGC) of tempered austenitic stainless steels in boiling solutions of 65% HNO_3 and 27% of HNO_3+40 g/l Cr"6"+ was investigated. It is ascertained that under the action of carbon additions susceptibility of phosphorus-containing steels to IGC increases considerably in pure nitric acid and decreases in nitric acid containing the oxidant. Possible reasons for the effects observed are discussed.
A method is described for increasing pressure in geologic oil-bearing structures by gas production due to microbial activity. There is added to an oil-bearing structure an anaerobic micro-organism (Methanobacterium termoautotroficum), a culture medium and formic acid. The formic acid is converted to carbon dioxide and methane gases resulting in increased pressure in the structures. Methanobacterium termoautotroficum cannot split formic acid into CO/sub 2/ and H/sub 2/ but it can produce methane from these 2 gases. 4 claims.
Temperature-dependent (5-42 degrees C) 13C NMR spectra of albumin complexes with 90% isotopically substituted [1-13C]decanoic acids (3 mol of fatty acid per mol of albumin) showed a single peak at greater...Full Text Available
This paper presents the experimental measurements of the transmittivity of commercial grade stearic acid. The effects of temperature and thickness on transmittance have been studied. The study indicates that the effect of temperature on the transmittance of stearic acid in the liquid phase is not significant. However, it is highly dependent on temperature during the solidification process. Because of its low thermal conductivity and high transmittivity, it can be used as a transparent insulating material. (Author)
Interactions of myristic acid with bovine serum albumin were studied by 13C NMR spectroscopy at 50.3 MHz using 90% isotopically substituted [1-13C]-, [3-13C]-, and [14-13C]myristic acids, either individually...Full Text Available
The emission of methane (1.3 mmol of CH4 m−2 day−1), precursors of methanogenesis, and the methanogenic microorganisms of acidic bog peat (pH 4.4) from...Full Text Available
Isotope ratios of cellulose and cellulose nitrate from aquatic Crassulacean acid metabolism (CAM) and non-CAM plants were determined. Cellulose oxygen istope ratios for all plants that grew together...Full Text Available
FT-IR spectrum of fulvic acid from wheathered coal of Gongxian is determined using second derivative spectroscopy and the spectroscopic resolution is enhanced. Moreover, FT-IR spectra of the complexes of fulvic acid with Ca"2"+, Ba"2"+, Cu"2"+, Pb"2"+ and UO_2"2"+ under different pH are determined and the nature of the coordination of these complexes is discussed.
Contents: Lead smelter operations generating SO2 and particulate; Sulfuric acid plant technology; Lead smelters with sulfuric acid plant SO2 control; Sulfuric acid plant operation with lead sinter machine problems and solutions; SO2 control for ASARCO lea...
Exogenous [14C]indole-3-acetic acid (IAA) is conjugated in citrus (Citrus sinensis) leaf tissues to one major substance which has been identified as indole-3-acetylaspartic...Full Text Available
By means of ESCA the composition and the thickness of passive films formed on austenitic stainless steels were investigated after the attack of nitric acid at various temperatures and acid concentrations. The outermost layers of the oxide film consist of SiO_2, then a layer rich of Cr-oxid follows, containing also some Mo in the four- and sixvalent state. Ni does not contribute to the oxide film. Cr is also enriched in the metal just below the oxide film. (orig.).
The report describes the site specific changes required to convert an existing lime FGD system to a limestone system enhanced by dibasic acid (DBA) or adipic acid, and the costs of making such a change. In 1982-83, pilot plant tests were conducted at the R. D. Green Station of Bi...
The NucliSens easyMAG and BioRot 9604 automated nucleic acid extraction systems were evaluated and compared with the manual QIAamp (Qiagen) extraction method for their abilities to extract nucleic acid...Full Text Available
Clavulanic acid, Z-(2R,5R)-3-(β-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0] heptane-2-carboxylic acid, has been shown to be an effective inhibitor of the β-lactamases of the...Full Text Available
Fatty acid biosynthesis from Na[1-14C]acetate was characterized in plastids isolated from primary roots of 7-day-old germinating pea (Pisum sativum L.) seeds. Fatty acid...Full Text Available
Fatty acid biosynthesis is crucial for all living cells. In contrast to higher organisms, bacteria use a type II fatty acid synthase (FAS II) composed of a series of individual proteins, making...Full Text Available
Acidic constituents in crude oil are associated with the formation of stable emulsions during production and present a challenge for efficient oil recovery and processing. Acid molecules, including naphthenic acids and acidic sulfur in crude oil cause corrosion in refineries and pipelines. Naphthenic acids are also significant because of their surface activity and marginal water solubility, so that they may leach to wastewaters and cause adverse environmental effects. Acidic components of oil are not limited to carboxylic acids but also molecules that contain sulfur and nitrogen. As such, an improved understanding of the chemistry and physics of petroleum at the molecular level is needed in order to understand the range of problems associated with acidic oil components and to design better solutions. The applications of ...
A simple procedure is described for preparing {sup 125}I-labelling hyluronan of high molecular weight. The reducing terminal group of hyaluronic acid was derivatized with tyramine through the formation of a Schiff base which was subsequently reduced with sodium cyanoborohydride. By radioiodination of the aromatic ring, {sup 125}I-labelled hyaluronic acid was obtained in high yield (40%) and high specific activity, 555 GBq/mmol (15 Ci/mmol). (Author).
1-Naphthylphthalamic acid (NPA) is a specific inhibitor of polar auxin transport that blocks carrier-mediated auxin efflux from plant cells. To allow identification of the NPA receptor thought to be...Full Text Available
The treatment of peat with the solutions of phosphoric, citric, and oxalic acids in concentrations of 10???4 and 10???2 mol/l at solid phase to liquid ratios of 1: 2.5 and 1: 5 increased the absorption of ammonia by 6.4???39.7%. The absorption of ammonia was higher than the concentration of doping ion-exchange groups by a factor of 5???2000. With the use of EPR and IR spectroscopy, it was found that this phenomenon was caused by the transformation of polyconjugation systems as a result of the interaction of acids with the organic matrix of peat by a macrocoordination mechanism, which also improved the technological characteristics of the resulting sorbents. The absence of the destruction of organic matter with the use of low concentrations of weak acids makes it possible to use these sorbe...
A novel microcapsule adsorbent for separation of uranium from phosphoric acid solutions was developed by immobilizing the di(2-ethylhexyl) phosphoric acid-?trioctyl phosphine oxide extractants in the polymeric matrix of calcium alginate. Physical characterization of the microcapsules was accomplished by scanning electron microscopy and thermogravimetric techniques. Equilibrium experiments revealed that both ion exchange and solvent extraction mechanisms were involved in the adsorption of Formula Not Shown ions, but the latter prevailed in a wider range of acid concentration. According to the results of kinetics study, at low acidity level, the rate controlling step was slow chemical reaction of Formula Not Shown ions with the microdroplets of extractant, whereas it changed to intraparticle...
The invention is regeneration and recirculation of nitrogen oxides in the exhaust gas of a nitric acid plant without using any material current and heat energy other than that generated in the process of producing nitric acid. Nitrogen oxide is recovered by at least two adsorbers each containing an acid resistant zeolite molecular sieve and operating in an alternate heat cycle; adsorption occurring at 20-40 degrees C and regeneration at 300-350 degrees C. The hot gas exiting from the oxidation U used in the production of nitric acid is used to regenerate the adsorbers and the nitrogen oxides set free during the said regeneration are introduced into the main feed stream of the nitric acid plant. In the final stage of the regeneration the adsorbers are cooled by rinsing them with exhaust gas or air at a temperature of 20-40 degrees C.
This work reports phase equilibrium measurements for the ternary systems linoleic (acid+CO2+ethanol) and (linolenic acid+CO2+ethanol). The fatty acids present in the ternary systems were selected based on composition of banana peel oil extracted by supercritical CO2 at 20MPa and 313K. The motivation of this research relies on the fact that these unsaturated fatty acids are recognized to play an important role in lowering blood pressure and serum cholesterol and because they are present in high concentrations in banana peel extract. Besides that, equilibrium data of these compounds are scarce in literature. The phase equilibrium experiments were performed using a high-pressure variable-volume view cell over the temperature range of (303 to 343)K and pressures up to 19MPa. For both systems, ...
A kinetic study of the degradation by ozone of eight phenolic acids present in wastewaters from olive oil mills has been performed by using a competition kinetic method. The selected phenolic acids are: caffeic, p-coumaric, syringic, vanillic, 3,4,5-trimethoxybenzoic, veratric, p-hydroxy-benzoic, and protocatechuic. The influence of the operating variables (temperature, pH, and ozone partial pressure in the gas stream) is established, and the stoichiometric ratios for the individual direct reactions between ozone and each acid are determined. Once the reaction rate constants are evaluated, they are correlated as a function of temperature and pH into kinetic expressions which are provided for every phenolic acid. The global process occurs in the fast and pseudo-first-order kinetic regime of absorption, a condition required by the competition model to be used.
Desulphurization of gasoline and kerosene was carried out using organic and inorganic oxidants. Among the organic oxidants used were hydrogen peroxide in combination with acetic acid, formic acid, benzoic acid and butyric acid, while inorganic oxidants used included potassium permanganate and sodium perchlorate. The oxidation of each petroleum oil was carried out in two steps; the first step consisted of oxidation of the feed at moderate temperature and atmospheric pressure while in the second step, the oxidized mixture was extracted with azeotropic mixture of acetonitrile-water. A maximum desulphurization has occurred with NaClO4 and hydrogen peroxide and acetic acid, which are 68% and 61%, respectively in case of gasoline and 66% and 63%, respectively in case of kerosene oil. The FTIR st...
A central composite design was employed to optimize the extraction of pectin with citric acid. The independent variables were citric acid concentration (0.086-2.91% w/v) and extraction time (17-102min). The combined effect of these variables on the degree of esterification was investigated. Results have shown that the generated regression models adequately explained the data variation and significantly represented the actual relationship between the independent variables and the responses. Besides that, the citric acid concentration was the most important factor to affect the degree of esterification, as it exerted a significant influence on the dependent variable. Lower citric acid concentration increased the pectin degree of esterification. The surface response showed the relationships b...
This patent describes a method of reducing the hydrogen sulfide level in streams containing hydrogen sulfide at concentrations from about 2 ppm up to about 1,000 ppm. It comprises reacting the hydrogen sulfide with an unsaturated hydrocarbon in the presence of an acidic solid catalyst selected from the group consisting of polymeric sulfonic acid resins, solid polyphosphoric acid, supported sulfuric acid, supported boric acid, silica-aluminas, clays, faujasite, mordenite, and L, omega, X or Y zeolites at mercaptan-forming concentrations, and recovering a stream having a reduced hydrogen sulfide concentration and containing no more than 5 ppm hydrogen sulfide.
The kinetics of the solubilization of lauric acid, palmitic acid, stearic acid, and monopalmitin have been studied in detergent solutions as a function of concentration, temperature, and fluid flow. The detergents used were sodium dodecyl sulfate (an anionic surfactant), decyltrimethylammonium bromide (a cationic surfactant), sodium taurocholate (a trihydroxy bile salt), sodium taurodeoxycholate (a dihydroxy bile salt), and triton X-100 (a nonionic surfactant). At low temperature, solubilization can be described by a five-step mechanism is which micelle desorption and diffusion are rate controlling. At temperatures above the fatty acid penetration temperature, solubilization is governed by formation of a liquid crystalline phase at the fatty acid-detergent solution interface.
Interaction of periodic and iodic acids with propyoneamide in aqueous solutions at 25 deg C has been studied. In the system iodic acid-propyoneamide-water formation of two compounds of the composition 6C_2H_5CONH_2#centre dot#HIO_3 and C_5H_5CONH_2#centre dot#HIO_3 is ascertained, for which concentrational boundaries of formation, density, melting points are determined. The system periodic acid-propyoneamide-water is referred to the simple eutonic type. By the method of IR spectroscopy it has been shown that oxygen atom of amide carbonyl group is the centre of propyoneamide protonation by iodic acid.
Summary Fruit vinegar can be obtained biologically from the fermentation of fruit wine using species of the genera Acetobacter. However, the productivity of vinegar is generally low because of the inhibition by substrate ethanol and product acetic acid. In this research, the yield of acetic acid, as well as the cell growth, in hawthorn vinegar fermentation was enhanced using beer for seed preparation. The higher yield of acetic acid of AC2005 was because of the higher alcohol dehydrogenase and aldehyde dehydrogenase activities caused by using beer for seed preparation. Furthermore, Acetobacter pasteurianus AC2005 showed acid stability during the fed batch fermentation of hawthorn vinegar.
Extraction of rare earths (La, Ce, Pr, Eu, Gd, Er, Yb) from nitrate solutions by melts of carboxylic acids of the C/sub 17/-C/sub 20/ fraction and stearic acid with paraffin, depending on the temperature (60-90 deg), phase contact time and their volume ratio (O:B from 1:5 up to 1:100), pH of the aqueous phase (2-6), rare earth concentration (10/sup -6/-10/sup -3/ m) is studied. It is shown that in the whole concentration range investigated rare earths are extracted quantitatively into the carboxylic acid melt of C/sub 17/-C/sub 20/ fraction at the equilibrium value of pH>=3.8, while into the melt of 0.1 M stearic acid in paraffin at pH>=4.5.
Young children are at increased risk for valproic acid (VPA) hepatotoxicity. Urinary organic acid profiles, as a surrogate of mitochondrial function, were obtained in children 1.9 to 17.3 years of age (n = 52) who were undergoing treatment with VPA for seizure disorders. Age-matched patients receiving treatment with carbamazepine (CBZ; n = 50) and healthy children not undergoing treatment (n = 22) served as controls. Age-related changes in organic acid profiles were observed in all three groups. Although the untreated and CBZ control groups were indistinguishable from each other with respect to the principal-component analysis (PCA) score plots of the subjects, a distinct boundary was apparent between the VPA and each of the control groups. Interindividual variability was observed in the V...
An Ultra-Low-Carbon 19% Cr-11% Ni Stainless Steels used in nuclear fuel reprocessing plants where highly corrosion resistance in nitric acid is required has been developed. This steel has optimized the chemistry composition to decrease inclusions and deformation-induced martensitic transformation. The formation of deformation-induced martensite has the potential danger of accelerating corrosion in nitric acid. In this paper, effects of cold reduction and martensitic transformation on corrosion resistance of Ultra-Low-Carbon Stainless Steels in nitric acid are discussed. The developed steel showed excellent corrosion resistance during long-term exposure to nitric acid. (author).
A red basil cell line (T2b) rich in rosmarinic acid (RA) was selected for the stable production of anthocyanins (ACs) in the dark. Cell suspension cultures were subjected to mechanical stress through increased agitation (switch from 90 to 150rpm) to determine the relationship between AC and RA accumulation. Cell extracts were analyzed by HPLC and LC-MS, and the resulting data were processed with multivariate statistical analysis. MS and MS/MS spectra facilitated the putative annotation of several complex cyanidin-based ACs, which were esterified with coumaric acid and, in some cases, also with malonic acid. It was also possible to identify various RA-related molecules, some caffeic and coumaric acid derivatives and some flavanones. Mechanical stress increased the total AC and RA contents, ...
Abstract NorUDCA (24 norursodeoxycholic acid), the C23 homolog of ursodeoxycholic acid (UDCA), showed remarkable therapeutic effects in cholestatic Mdr2 (Abcb4) (multidrug resistance protein 2/ATP binding cassette b4) knockout mice with sclerosing/fibrosing cholangitis. In contrast to UDCA, norUDCA is inefficiently conjugated in human and rodent liver, and conjugation has been discussed as a key step for the anticholestatic action of UDCA in cholestasis. We compared the choleretic, anticholestatic, and antiapoptotic properties of unconjugated and taurine conjugated UDCA (C24) and norUDCA (C23) in isolated perfused rat liver (IPRL) and in natrium/taurocholate cotransporting polypeptide (Ntcp) transfected human hepatoma (HepG2) cells. Taurolithocholic acid (TLCA) was used to induce a predomi...
A spectrophotometric study has been made of the complex formation of vanadium (3) with arsenazo(1), arsenazo(3) and some monosubstituted derivatives of chromotropic acid and sulphanylamides. In acid medium vanadium (3) reacts with each of these reagents to produce a 1:1 complex. Optimum conditions of the complex formation was found. The effect of H"+ on the complex formation of vanadium (3) with chromotropic acid derivatives was established. It was found by the graphical method that the formation of the complex is accompanied by the elimination of one proton. Patterns were found of the influence of the nature of substituents in the organic compound on the ionization constants of acid groups and stability of complexes. Molar extinction coefficients, equilibrium constants of the formation reactions and instability constants for the complexes were calculated. The structure of complexes was suggested. ...
The authors investigate the corrosion and anodic behavior of steels 12Kh18N10T, 08Kh21N6M2T, and 06KhN28MDT, nickel, and molybdenum in 10-40% naturally aerated solutions of H/sub 2/TiF/sub 6/ at 20 and 50 degrees C. The authors found that in solutions of fluotitanic acid, as also in tetrafluoroboric and hydrofluoric acids, the most stable alloys are chromium-nickel-molybdenum alloy of type 06KhN28MDT and (for acid concentrations above 20%) copper-nickel-alloys of the monel metal type. Steels 12Kh18N10T and 08Kh21N6M2T can be used in acid concentrations of less than 10% and temperatures up to 20 degrees C with anodic protection.
The authors investigate the corrosion and anodic behavior of steels 12Kh18N10T, 08Kh21N6M2T, and 06KhN28MDT, nickel, and molybdenum in 10-40% naturally aerated solutions of H_2TiF_6 at 20 and 50 degrees C. The authors found that in solutions of fluotitanic acid, as also in tetrafluoroboric and hydrofluoric acids, the most stable alloys are chromium-nickel-molybdenum alloy of type 06KhN28MDT and (for acid concentrations above 20%) copper-nickel-alloys of the monel metal type. Steels 12Kh18N10T and 08Kh21N6M2T can be used in acid concentrations of less than 10% and temperatures up to 20 degrees C with anodic protection.
An oxidative method for enriching the content of humic acids in a mined lignite from Umbria (central Italy) is described. A mild oxidation using H{sub 2}O{sub 2} in an alkaline medium was successful in increasing the percentage of lignite-derived humidifed carbon from 5.77% to 33.67%. The newly formed humic acids showed a higher number of oxygen-bearing functional groups, a lower carbon/oxygen ratio and a higher absorbance ratio at 465 and 665 nm (E{sub 4}/E{sub 6}) in diluted solution compared to the native lignite-derived humic acids. A high E{sub 4}/E{sub 6} ratio indicated less condensation of the aromatic nucleus and a lower molecular weight in comparison to the lignite-derived native humic acids.
In vitro cytocompatibility and cellular interactions of lauric acid and dextran-coated magnetite nanoparticles were evaluated with two different cell lines (mouse fibroblast and human cervical carcinoma). Lauric acid-coated magnetite nanoparticles were less cytocompatible than dextran-coated magnetite nanoparticles and cellular uptake of lauric acid-coated magnetic nanoparticles was more than that of dextran-coated magnetite nanoparticles. Lesser cytocompatibility and higher uptake of lauric acid-coated magnetite nanoparticles as compared to dextran-coated magnetic nanoparticles may be due to different cellular interactions by coating material. Thus, coating plays an important role in modulation of biocompatibility and cellular interaction of magnetic nanoparticles.
In vitro cytocompatibility and cellular interactions of lauric acid and dextran-coated magnetite nanoparticles were evaluated with two different cell lines (mouse fibroblast and human cervical carcinoma). Lauric acid-coated magnetite nanoparticles were less cytocompatible than dextran-coated magnetite nanoparticles and cellular uptake of lauric acid-coated magnetic nanoparticles was more than that of dextran-coated magnetite nanoparticles. Lesser cytocompatibility and higher uptake of lauric acid-coated magnetite nanoparticles as compared to dextran-coated magnetic nanoparticles may be due to different cellular interactions by coating material. Thus, coating plays an important role in modulation of biocompatibility and cellular interaction of magnetic nanoparticles.
The verification test program on zinc injection applicability to Japanese BWRs was started in 1997. Laboratory tests using high temperature water loops under BWR reactor water conditions are in progress. This paper is an interim report on results obtained so far. Co-58 and Zn-65 were simultaneously used in the Co radioactivity buildup test to evaluate zinc injection suppression effects towards cobalt deposition on pre-oxidized stainless steel. The following results were obtained. The Co deposition was suppressed effectively by Zn injection, even when there was a pre-oxide film. For the test piping that had the pre-oxide film formed under the NWC (normal water chemistry) condition, when soaked under the HWC (hydrogen water chemistry) condition a large amount of Co-58 was taken into a small part of the inner layer. The distribution ratio of Co-58 in the inner layer and outer layer of the oxide film was almost the same for both the pre-oxidized test piping and the non pre-oxidized test ...
The retina consists of many kinds of central nervous cells, and some cells contain fatty acids such as palmitic acid, stearic acid and oleic acid. Time-of-flight secondary ion mass spectrometry (TOF-SIMS) has a possibility to detect kinds and quantity of materials in relation to the cell or tissue. We applied TOF-SIMS to detect the palmitic acid, stearic acid and oleic acid in the visual cell of the rat retina. We used 4- and 18-month-old normal Wistar Kyoto rats. After pentobarbital anesthesia, the eyes were enucleated, and immediately put into liquid nitrogen without any fixation and then cut into semithin sections (10 {mu}m) with a cryo-ultramicrotome, and laid it on a silicon wafer plate and air-dried. Ion images were detected with TOF-SIMS. Positive ion images were examined with a Ga{sup +} source at an acceleration voltage of 15 keV. ...
Project RPS116, ''Implementation of Boric Acid in the Field,'' was designed to demonstrate that a selected steam generator boric acid treatment is effective in arresting the progressing of denting in an operating steam generator. The PWR nuclear steam generators chosen for the testing were those at the Indian Point Unit 3 nuclear site. Hydrogen monitoring measurements and eddy current examinations had indicated that the Indian Point Unit 3, Series 44 steam generators had already reached an advanced stage of denting and tube support plate ligament discontinuities were observed. The objective of the boric acid treatment was to reduce the rate of denting by attempting to reproduce in the field the positive results achieved with boric acid in laboratory-simulated denting tests. Laboratory testing has indicated that implementation of a four day low power (25% power) boric acid soak with ...
The effects of the structure of a carboxylic acid on the processes of oxidation and reduction of iron ions in irradiated aqueous solutions were directly observed during irradiation. The solutions contained the mono- or dicarboxylic acid, H/sub 2/SO/sub 4/, Fe(NH/sub 4/)/sub 2/(SO/sub 4/)/sub 2/ and O/sub 2/. Th e ferrous oxidation was rather independent of the acid and its concentration, but the reduction of ferric was possible in the presence of formic, oxalic, or valeric acid only. The radical formed from the valeric acid acts similar to those formed from hydrocarbons. The G-values of oxidation and reduction of the iron ions were established. The molar extinction coefficients for oxalic and malonic complexes of ferric ions were determined. (auth)
Three dispersants (stearic acid, oleic acid, and poly-(12-hydroxystearic acid)) are compared for their ability to produce low-viscosity suspensions of zirconia in kerosene. Rheological measurements and sediment packing density measurements show that poly(12-hydroxystearic acid) is a better dispersant than stearic acid or oleic acid; this is explained in terms of the longer tail of the poly-(12-hydroxystearic acid) surfactant molecule. The amount of dispersant can be optimized to reduce viscosity and yield point of the suspension, and to eliminate thixotropic hysteresis. The use of a dispersion medium of lower viscosity than the dispersant makes it easy to detect when complete monolayer coverage has been achieved. The loss of pseudoplasticity, brought about by a higher degree of deflocculation, can be recovered by increasing the volume ...
A cellular membrane exchanges substances into and from the cell and protects the cell interior by maintaining semi-fluidity rather than be being solid. It is known that microorganisms maintain the fluidity in correspondence with varying environmental temperatures by changing and adjusting the composition of fatty acids which constitute the cellular membrane lipids. As part of the studies to elucidate the pressure withstanding mechanism in deep-sea bacteria, this paper investigates what variations the fatty acid composition, which constitutes cellular membranes of the DSS12 strain, a pressure withstanding bacterium growing well under either normal pressure or high pressures, will show under different culturing temperatures and pressures. Culture under low temperatures and culture under high pressures increase content of unsaturated fatty acids including icosapentanoic acid. Culture under high ...
The software package VIBA-lab1, which incorporates PIXE and RBS energy spectra simulation has now been extended to include the simulation of elemental maps from 3D structures. VIBA-lab1 allows the user to define a wide variety of experimental parameters, e.g. energy and species of incident ions, excitation and detection geometry, etc. When the relevant experimental parameters as well as target composition are defined, the program can then simulate the corresponding PIXE and RBS spectra. VIBA-LAB2 has been written with applications in nuclear microscopy in mind. A set of drag-and-drop tools has been incorporated to allow the user to define a three-dimensional sample object of mixed elemental composition. PIXE energy spectra simulations are then carried out on pixel-by-pixel basis and the corresponding intensity distributions or elemental maps can be computed. Several simulated intensity distributions for some 3D objects are demonstrated, and ...
Following tuber excision from the mother plant sucrose synthase activity fell from 3,120 to 960 nmol/g.f. wt./h within 7 days and starch synthesis ({sup 14}C sucrose incorporated into isolated discs) from 23 to 7 nmol/g.f. wt./h. While the maximum catalytic activity of sucrose synthase was more than sufficient to account for the observed rate of starch synthesis a maximum of 27% of sucrose incorporated by discs was converted into starch within 3 h. This compared with 80% conversion of {sup 14}C glucose incorporated. Tuber excision also reduced the rate of starch biosynthesis with glucose as a substrate (from 206 to 64 nmol/g.f. wt./h). The activities of UDPG-pyrophosphorylase, PPi-PFK, ATP-PFK, starch synthase and hexokinase (glucose or fructose substrates) were unaffected by tuber removal. ADPG pyrophosphorylase activity was reduced from 8,000 to 4,500 nmol/g.f. wt./h. Preliminary experiments indicate that the decline in ...
Fluorine is known to have a beneficial role for the B diffusion reduction in preamorphized Si, and is promising for the realization of ultra-shallow junctions. Thus, we studied the F incorporation in Si during the solid phase epitaxy (SPE) process, pointing out the effects of the implanted F energy and fluence and the role played by the possible presence of dopants. The incorporation of fluorine proceeds by F segregation at the amorphous-crystalline interface, with a kinetics driven by the SPE rate. In fact, the quicker the SPE rate, the higher is the F fluence retained. Moreover, we demonstrated that F incorporated in Si layers does not appreciably affect the Is emission from spatially separated end-of-range (EOR) defects. The modification, induced by the presence of F, of the point defect density (Is and Vs) was also studied by means of B and Sb spike layers, used as local markers for Is and Vs, respectively. We showed ...
Advanced proteomic research efforts involving areas such as systems biology or biomarker discovery are enabled by the use of high level informatics tools that allow the effective analysis of large quantities of differing types of data originating from various studies. Performing such analyses on a large scale is not feasible without a computational platform that performs data processing and management tasks. Such a platform must be able to provide high-throughput operation while having sufficient flexibility to accommodate evolving data analysis tools and methodologies. The Proteomics Research Information Storage and Management System (PRISM) provides a platform that serves the needs of the accurate mass and time tag approach developed at PNNL. PRISM incorporates a diverse set of analysis tools and allows a wide range of operations to be incorporated by using a state machine that is accessible to independent, distributed computational nodes. ...
This paper proposes a new pattern recognition system employing optical joint transform correlation (JTC) technique which offers a great number of advantages over similar digital techniques, including very fast operation, simple architecture and capability of updating the reference image in real time. The proposed JTC technique incorporates a synthetic discriminant function (SDF) of the target image estimated from different training images to make the pattern recognition performance invariant to noise and distortion. It then involves four different phase-shifted versions of the same target SDF reference image, which are individually joint transform correlated with the given input scene. When the correlation signals are combined, it produces a single cross-correlation peak corresponding to each potential target present in the given input scene. The proposed technique also includes a fringe-adjusted filter to generate a delta-like correlation peak with high ...
A study was made of the actions of the excitant neurotoxin, kainic acid, on the uptake and the release of D-(2,3-3H)aspartate (D-ASP) in slices of guinea pig cerebral neocortex and striatum. The slices took up D-ASP, reaching concentrations of the amino acid in the tissue which were 14-23 times that in the medium. Subsequently, electrical stimulation of the slices evoked a Ca2+-dependent release of a portion of the D-ASP. Kainic acid (10(-5)-10(-3) M) produced a dose-dependent inhibition of D-ASP uptake. The electrically evoked release of D-ASP was increased 1.6-2.0 fold by 10(-5) and 10(-4)M kainic acid. The kainate-enlarged release was Ca2+-dependent. Dihydrokainic acid, an analogue of kainic acid with little excitatory or toxic action, did not increase D-ASP release but depressed D-ASP uptake. Attempts were made to block the action of kainic ...
We report the influence of a small quantity of Cl[sub 2], which enhanced the selectivity of silicon-selective epitaxial growth (Si-SEG) in UHV-CVD using Si[sub 2]H[sub 6], on both the epitaxial growth rate and the B-doping properties for each Si and Si[sub 1-x]Ge[sub x] film. The small quantity of Cl[sub 2] inhibited the Si, Ge and B incorporation, while the selectivity was enhanced. However, it was found, in the case of Si[sub 1-x]Ge[sub x]-SEG using Cl[sub 2], that the reduction ratio of both the growth rate and the B incorporation were smaller than those of Si-SEG with the selectivity still more enhanced. (orig.)
Abstract Ecosystem processes function at many scales, and capturing these processes is a challenge for ecosystem models. Nevertheless, it is a necessary step for considering many management issues pertaining to shelf and coastal systems. In this paper, we explore one method of modeling large areas with a focus at a range of scales. We develop an ecosystem model that can be used for strategic management decision support by modeling the waters off southeastern Australia using a polygon telescoping approach, which incorporates fine-scale detail at the coastal zone, increasing in scale to a very coarse scale in the offshore areas. This telescoping technique is a useful tool for incorporating a wide range of habitats at different scales into a single model.
The growth and properties of Si{sub 1{minus}y}C{sub y} and Si{sub 1{minus}x{minus}y}Ge{sub x}C{sub y} alloys pseudomorphically strained on Si(001) will be reviewed. Although the bulk solubility of carbon in silicon is small, epitaxial layers with more than 1 at.% C can be fabricated. The relation between substitutional and interstitial carbon incorporation will be presented. Substitutionally incorporated C atoms allow strain manipulation, including the growth of strain-free or inversely strained Si{sub 1{minus}x{minus}y}Ge{sub x}C{sub y} layers. The mechanical properties, microscopic structure, thermal stability, as well as the influence of C atoms on band structure will be discussed.
Two relativistic approaches are considered to evaluate the quasielastic double-differential and integrated neutrino-nucleus cross sections. One, based on the relativistic impulse approximation, relies on the microscopic description of nuclear dynamics using relativistic mean field theory, and incorporates a description of the final-state interactions. The second is based on the superscaling behavior exhibited by electron scattering data and its applicability, due to the universal character of the scaling function, to the analysis of neutrino scattering reactions. The role played by the vector meson-exchange currents in the two-particle two-hole sector is also incorporated and the results obtained are compared with the recent data for neutrinos measured by the MiniBooNE Collaboration.
The goal of this research program is to determine whether pulsed laser deposition is an effective alternative method for growing TiCN thin films. Pulsed laser deposition (PLD) is chosen because of its well-documented capability for growing uniform, stoichiometric films in ultra-high vacuum or gaseous environments. Processing of thin films by PLD is also achieved at relatively low temperatures compared with CVD processing. Given these attributes, the primary objectives in this article are to determine whether nitrogen may be readily incorporated into films resulting from the laser-ablation of TiC in an N{sub 2} environment, determine what effect nitrogen has on mechanical properties, and determine whether nitrogen incorporation is strongly influenced by processes unrelated to laser deposition (e.g., thermally-activated surface reactions).
Abstract Preparation of antibacterial alginate films incorporating extruded white ginseng (EWG) extracts was attempted. The antibacterial effect of EWG extract on six selected food pathogenic bacteria was compared with the effect of red ginseng (RG) and white ginseng (WG) extracts. The EWG was processed in a twin-screw extruder with feed moisture of 20% and barrel temperature of 115 and 130C. The data obtained by agar diffusion assay demonstrated that the film containing 1-g/mL of EWG at barrel temperatures of 115 (EWG-115) and 130C (EWG-130) exhibited stronger antibacterial activity against the four strains of bacteria than the other extracts RG and WG. All films sampled showed reduction in bacteria cell counts (log cycle) compared with the control. After 24-h of incubation, Pseudomonas a...
Microgel-clay composite particles were prepared by one-step surfactant-free precipitation polymerization. Laponite nanoparticles present in the reaction mixture become encapsulated during the microgel formation process. Microgel-clay composites based on poly(N-vinylcaprolactam-co-acetoacetoxyethyl methacrylate) containing different amount of incorporated clay nanoparticles were synthesized. The clay content was varied from 2 wt% to 18 wt%. The extremely high incorporation efficiency of the clay nanoparticles into microgels was detected. The size of the hybrid microgels was decreased from 700 nm to 100 nm by increase of the clay concentration in the reaction mixture. Obtained hybrid microgels exhibit negative surface charge and excellent colloidal stability. Microgel-clay composite particle...
It has been demonstrated that, by incorporating a thin #approx#20 nm Si_1_-_yC_y (with y as low as 0.1%) layer at the deep indium implant end-of-range (EOR) region, the EOR defects and enhanced diffusion behavior associated with indium implant can be eliminated. The Si_1_-_yC_y layer was grown epitaxially followed by a silicon epitaxy cap of 60 nm. Indium implantations were performed at 1x10"1"4 cm"-"2 at 115 keV followed by spike annealing at 1050 deg. C. The experimentally observed EOR defect and enhanced diffusion elimination are explained based on the undersaturation of implantation-induced silicon interstitials with the presence of substitutional carbon at the Si_1_-_yC_y layer.
Cavity ringdown spectroscopy (CRDS) with continuous-wave (cw) laser excitation has added high frequency resolution to the ability of CRDS being used for the absolute quantification of trace-level species present in many chemical processes. Cavity dithering technique has easily resolved the problem of resonant coupling of a cw laser light into a high-finesse cavity. The present study addresses the potential uncertainty involved in such cw-CRDS techniques incorporating the cavity mirror motion, i.e., the doppler frequency shift of a probe light inside the cavity. In the high-resolution spectroscopic work of megahertz-accuracy, even the influence of intracavity doppler effect may become significant.
Google's Android is a comprehensive software framework for mobile communication devices (i.e., smartphones, PDAs). The Android framework includes an operating system, middleware and a set of key applications. The incorporation of integrated access services to the Internet on such mobile devices, however, increases their exposure to damages inflicted by various types of malware. This paper provides a comprehensive security assessment of the Android framework and the security mechanisms incorporated into it. A methodological qualitative risk analysis that we conducted identifies the high-risk threats to the framework and any potential danger to information or to the system resulting from vulnerabilities that have been uncovered and exploited. Our review of current academic and commercial solutions in the area of smartphone security yields a list of applied and recommended defense mechanisms for hardening mobile devices in general and the Android ...
The Goldstone-Brueckner perturbation theory is extended to incorporate in a simple way correlations associated with large amplitude collective motions in nuclei. The new energy expansion making use of non-orthogonal vacua still allows to remove the divergences originating from the hard-core of the bare interaction. This is done through the definition of a new Brueckner matrix summing generalized Brueckner ladders. At the lowest-order, this formalism motivates variational calculations beyond the mean-field such as the Generator Coordinate Method (GCM) and the Projected Mean-Field Method from a perturbative point of view for the first time. Going to higher orders amounts to incorporate diabatic effects in the GCM and to extend the projection technique from product states to well-defined correlated states.
Three different guidelines define the methods to be used for the quantification of exposures due to the incorporation of radionuclides. The adoption of the Euratom-directive into German law requires the adaptation of these guidelines. With this process, the experiences with the practical application of these regulations must be taken into account. (orig.) [Deutsch] Die Ermittlung der Koerperdosis durch inkorporierte Radionuklide ist in drei Richtlinien des Bundesministeriums fuer Umwelt, Naturschutz und Reaktorsicherheit (BMU) geregelt. Die Umsetzung der Euratom-Direktive in deutsches Recht erfordert die Anpassung dieser Richtlinien. Dabei muessen die bisherigen Erfahrungen mit diesen Richtlinien beruecksichtigt werden. (orig.)
The concept of antimicrobial packaging has received great attention because of its potential to enhance food safety. Several studies have explored its applications and effectiveness to suppress pathogenic microorganisms. However, few studies have analyzed the alterations caused in the engineering properties of food-packaging polymers after the incorporation of antimicrobials. Such information is very important to understand the feasibility of producing antimicrobial packaging films on the industrial scale. This review explores the work done so far to evaluate how the incorporation of antimicrobial substances affects the properties of food-packaging systems. This article also emphasizes diffusion studies on antimicrobial substances through packaging films and the analytical solutions used t...
We have investigated the effect of manganese (Mn) doping on properties of nanosized biphasic calcium phosphate powders and their dense bodies. Manganese levels of 0.6, 1.3, 1.9, 4.3, 7.0 and 11.9at.% were successfully incorporated into biphasic calcium phosphate via a sol-gel route. The prepared powders were calcined at temperatures of 500-1200^oC. The X-ray diffraction analysis revealed that a mix phase comprising of hydroxyapatite and @b-tricalcium phosphate were present, however the content of each phases in the structure was affected by the Mn content. The studies found that the largest portion of @b-tricalcium phosphate was detected at 4.3at.% Mn doping. The incorporation of Mn has also greatly increased the crystallinity of the biphasic calcium phosphate powder due to progressive den...
The physical and antioxidant properties of alginate biodegradable film incorporating white, red and extruded white ginseng extracts were investigated. No differences in moisture contents of all alginate film samples were noticeable (p>0.05) except those film samples incorporated without ginseng extract, which had the highest moisture content. The addition of ginseng extract to alginate film decreased tensile strength and elastic modulus (p<0.05) but increased the percent elongation at break. The presence of extracts did not significantly affect the water vapor permeability of the film samples. Alginate film containing extruded white ginseng extract at a barrel temperature of 130degreeC presented the highest (61.12%) free-radical scavenging activity against the 2,2-diphenyl-1-picryhydrazyl ...
The final report for a Laboratory Directed Research and Development project entitled, ``Capturing Recrystallization of Metals in a Multiscale Materials Model'' is presented. In this project, deformation and recrystallization processes have been followed experimentally and theoretically in order to incorporate essential mechanisms from the defect (dislocation) and grain size length scales. A nonlinear rotational gradient theory has been developed which enables the incorporation of microstructural parameters. The evolution of these parameters during deformation and recrystallization has been characterized qualitatively and quantitatively, applying various electron optic techniques ranging over several length scales. The theoretical and experimental framework developed is general. It has been exemplified by an application to recrystallization in single crystals and bicrystals of aluminum. The recrystallization process has been ...
With the rapid growth of Information and Communication Technology, Electronic commerce is now acting as a new means of carrying out business transactions through electronic means such as Internet environment. To avoid the complexities associated with the digital cash and electronic cash, consumers and vendors are looking for credit card payments on the Internet as one possible time-tested alternative. This gave rise of the on-line payment processing using a third-party verification; which is not suitable for the developing countries in most of the cases because of the excessive costs associated with it for maintenance and establishment of an online third-party processor. As a remedy of this problem, in this paper, we have proposed a framework for easy security incorporation in credit card based electronic payment system without the use of an on-line third- party processor; which tends to be low cost and effective for the developing countries.
Nowadays there are many sun-protection cosmetics incorporating organic or inorganic UV filters as active ingredients. Chemically stable inorganic sunscreen agents, usually metal oxides, are widely employed in high-SPF (sun protection factor) products. Titanium dioxide is one of the most frequently used inorganic UV filters. It has been used as a pigment for a long period of cosmetic history. With the development of micronization techniques, it has become possible to incorporate titanium dioxide in sunscreen formulations without the previous whitening effect, and hence its use in cosmetics has become an important research topic. However, there are very few works related to quantitation of titanium dioxide in sunscreen products. In this research, we analysed the amounts of titanium dioxide i...
It has been previously stated that the minimum physiological recommendations for the indispensable amino acids in health adults, as proposed by FAO/WHO/UNU in 1985, are far too low, except for the methionine. An amino acid stable isotopic kinetic study was conducted to seek further experimental support to this hypothesis. Twenty healthy young men received an l-amino acid based diet, supplying 140 mg N.kg"-"1.d"-"1, patterned on egg protein for 1 week, then for 3 weeks either i) a pattern based on current international recommendations (FAO diet, n=7), ii) a the tentative Laboratory of Human Nutrition of the Massachusetts Institute of Technology, new amino acid recommendation pattern (MIT diet, n=7) or iii) again the egg hen pattern (EGG diet, n=6). All subjects were again studied for one final, consecutive week of the egg diet. At the end of the initial week, at the first and third week with the three ...
Fatty acids such as stearic acid (SA), palmitic acid (PA), myristic acid (MA), and lauric acid (LA) are promising phase change materials (PCMs) for latent heat thermal energy storage (LHTES) applications, but high cost is the most drawback which limits the utility area of them in thermal energy storage. The use of fatty acids as form-stable PCM will increase their feasibilities in practical LHTES applications due to reduced cost of the energy storage system. In this regard, a series of fatty acid/poly(methyl methacrylate) (PMMA) blends, SA/PMMA, PA/PMMA, MA/PMMA, and LA/PMMA were prepared as new kinds of form-stable PCMs by encapsulation of fatty acids into PMMA which acts as supporting material. The blends were prepared at different mass fractions of fatty acids (50, 60, 70, 80, and 90% w/w) to ...
Simple hydroxamic acids have been shown to have useful applications in an Advanced Purex process for the reprocessing of irradiated nuclear fuel. They are especially suited to the separation of neptunium (IV) from uranium (VI) by the selective formation of a hydrophilic complex with Np(IV). U(VI) extraction in to 30% tributyl phosphate is unaffected. However, they have also been shown to be very fast reducing agents for Np(VI). The timescales of the reduction have been defined under a range of typical Purex Process conditions although the accurate determination of the reaction kinetics was not possible due to the rapidity of the reaction. U(VI) was shown not to be reduced. Therefore, Np(VI) can be efficiently reductively stripped when solvent phase (30% tributyl phosphate in odourless kerosene) solutions of Np(VI) and U(VI) are contacted with aqueous phase hydroxamic acid solutions. The slow reduction of plutonium (IV) to Pu(III) has also been ...
The effect of neutralizing cations on the secondary reactions of the primary products from CO hydrogenation over ion-exchanged zeolite-supported Ru catalysts was investigated using zeolites with different alkali cations (Li/sup +/, Na/sup +/, K/sup +/, Rb/sup +/, Cs/sup +/). The transformation of olefins (propylene and butene) on the zeolites without the metal, under conditions similar to those used for CO hydrogenation, was also studied in order to understand the effect of the various constituents of the support, i.e., the Broensted acid sites generated during catalyst preparation and the alkali cations, on possible secondary reactions of the primary olefinic products. It was established that secondary acid-catalyzed reactions of these primary products can play a major role in shaping product selectivity during CO hydrogenation over zeolite-supported catalysts. Depending on the concentration and the strength of the acid ...
One of the most effective removing processes of iodine species is what is called ''Iodox Process'', which contains oxidation and absorption of iodine species by highly concentrated nitric acid. The result of fundamental test with bubble column in this process had been reported. Present paper describes the fundamental experiment by the use of packed column. This experiment has been carried out to clear the effect of feed gas flow rate, nitric acid flow rate, nitric acid concentration, and methyl iodide concentration on removal efficiency of methyl iodide. The following results were obtained. The decontamination factor of methyl iodide (DF) increases exponentially with nitric acid concentration, which agrees with the result obtained by using the bubble column. The factor is in inverse proportion to feed gas flow rate, and is also almost independent of nitric acid flow rate and methyl ...
Recent progress in the metallic conducting Langmuir-Blodgett (LB) films built from TTF derivative and fatty acids is reported. A simple LB method of transferring the mixed Langmuir (L) film of BEDO-TTF (BO) and stearic acid (SA) onto substrates provided metallic conducting LB films. A homogeneous L film formation on the water surface observed by Brewster angle microscope (BAM) is an essential factor for the well-ordered LB films. In the L film, the carboxylate group of fatty acid forms anion layer bringing about a spontaneous formation of mixed valence state (MVS) of BO layer. Similar spontaneous formation was also found in the molecular combination of nonoxygen-substituted donor of EDT-TTF and octadecanesulfonic acid (OS). This type of reaction would be useful for obtaining conducting LB films. For the LB films of BEDO-TTF and stearic acid, we found a negative transverse ...
Radioactive particles as well as x irradiation from an external source has been used in the treatment of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. In order to clarify effects of ionizing irradiation on synovial cells, radioactive gold ("1"9"8Au) and yttrium ("9"0Y) were added to fibroblast cultures derived from human synovial membranes. Other cultures were irradiated by a Picker x-ray machine. Fibroblast growth and hyaluronic acid production were measured. Radioactive gold and yttrium particles induced a significant increase of hyaluronic acid synthesis rate (pg/cell/day) and inhibited fibroblast growth. Fibroblasts continued to overproduce hyaluronic acid and to show growth inhibition 3 weeks after irradiation with radioactive gold. Hydrocortisone inhibited hyaluronic acid overproduction induced by radioactive gold. Overproduction of hyaluronic acid induced ...
Homology analyses of the protein sequences of chicken liver and rat mammary gland fatty acid synthases were carried out. The amino acid sequences of the chicken and rat enzymes are 67% identical. If conservative substitutions are allowed, 78% of the amino acids are matched. A region of low homologies exists between the functional domains, in particular around amino acid residues 1059-1264 of the chicken enzyme. Homologies between the active sites of chicken and rat and of chicken and yeast enzymes have been analyzed by an alignment method. A high degree of homology exists between the active sites of the chicken and rat enzymes. However, the chicken and yeast enzymes show a lower degree of homology. The DADPH-binding dinucleotide folds of the {beta}-ketoacyl reductase and the enoyl reductase sites were identified by comparison with a known consensus sequence for the DADP- and FAD-binding dinucleotide ...
A procedure for the determination of carboxylic acids (benzoic and C{sub 8}-C{sub 16} aliphatic acids) in oxidised engine oils is described. It is based on a simple and selective derivatisation of the acids with a fluorescent label 9-anthracene-methanol followed by reverse-phase separation on an ODS column with a water-acetonitrile-tetrahydrofuran (20:40:40 by volume) mobile phase and post-column reaction with bis(2,4-dinitrophenyl) oxalate and hydrogen peroxide. The chemiluminiscence emission from the reaction was monitored using a lamina flow-through detector. Analysis of oxidised oils showed that although there was quenching of chemiluminiscence emission by the oil matrix, the acids could be determined over the range 0-0.4% (m/v) in the oil with a detection limit of 0.013% (m/v) (130 pmol on-column with a 20 {mu}l injection) for lauric acid. 8 figs., 2 tabs., 17 refs.
We report biological changes at several UK Acid Waters Monitoring Network lakes and streams that are spatially consistent with the recovery of water chemistry induced by reductions in acid deposition. These include trends toward more acid-sensitive epilithic diatom and macroinvertebrate assemblages, an increasing proportional abundance of macroinvertebrate predators, an increasing occurrence of acid-sensitive aquatic macrophyte species, and the recent appearance of juvenile (<1 year old) brown trout in some of the more acidic flowing waters. Changes are often shown to be directly linked to annual variations in acidity. Although indicative of biological improvement in response to improving water chemistry, 'recovery' in most cases is modest and very gradual. While specific ecological recovery endpoints are uncertain, it is likely that physical and biotic ...
A method of treating bitumina and allied substances of asphaltose character includes heating the material to be treated with up to 25% of its weight of a substance of the group consisting of vegetable and animal oils and fats and fatty acids. The resulting material is heated to a temperature of about 250/sup 0/C under sufficient pressure to prevent the material escape of sulfur dioxide from the reaction mixture in the presence of a substance of the group consisting of inorganic acids of sulfur containing at least 4 oxygen atoms and their anhydrides. The heating is continued until there is no free acid left in the reaction mass.
This paper presents the results of experimental study carried out to know whether the salicylic acid used as an additive during the precipitation of zirconium using ammonium hydroxide solution goes into the filtrate, remains in the hydrated zirconia or gets distributed between the both under the ambient conditions of precipitation. Keeping its simplicity and amenability to adopt on a routine basis, spectrophotometric method has been chosen for the purpose among the many methods available and the problems associated in determining salicylic acid in the presence of zirconium and the medial measures to circumvent the same have been brought out in detail. (author)
The thermodynamic framework that was developed in a previous work [Vrachnos et al. Ind. Eng. Chem. Res. 2004, 43, 2798] for the description of chemical and vapor-liquid equilibria of carbon dioxide, hydrogen sulfide, and their mixtures in aqueous methyldiethanolamine (MDEA) solutions is revised and extended in this study to the absorption of carbon dioxide into aqueous monoethanolamine (MEA) solutions and aqueous MDEA-MEA blends. The results of the model are compared with experimental data taken from the literature. Very satisfactory predictions of acidic gas vapor-liquid equilibrium over MDEA, MEA, and their blends at various concentrations, acidic gas loadings, and temperatures are obtained.
The chemical separation of carrier-free "2"0"3Pb following deuterium bombardment of a "2"0"3Tl target is described. Coprecipitation from strontium sulphate was used to separate the "2"0"3Pb from a solution of the thallium target in sulphuric acid. The SrSO_4 precipitate was filtered, washed and dissolved in hydrochloric acid, from which "2"0"3Pb was again separated by precipitation on sodium chloride from a strongly acid solution. Advantages of the system are discussed and optimum conditions given. (U.K.).
Sulfuric acid hydrogen peroxide mixtures (SPM) are commonly used in the semiconductor industry to remove organic contaminants from wafer surfaces. This viscous solution is very difficult to rinse off water surfaces. Various rinsing conditions were tested and the resulting residual acid left on the water surface was measured. Particle growth resulting from incomplete rinse is correlated with the amount of sulfur on the wafer surface measured by Time of Flight Secondary Ion Mass Spectroscopy (TOF-SIMS). The amount of sulfur on the wafer structure after the rinse step is strongly affected by the wafer film type and contact angle prior to the SPM clean.
Recovery of uranium by ion-exchange processes from impure acid leach liquors is described, which produce a concentrated and pure eluate employing 10% sulphuric acid elution. In situations where resin is loaded to 45 g/ltr or more the acid consumption at ambient temperature is less than 4 kg of H_2SO_4 per kilogram of U_3O_8. Precipitation with an alkali such as ammonia or magnesia produces a yellow cake of high purity. (author).
The chemical separation of carrier-free /sup 203/Pb following deuterium bombardment of a /sup 203/Tl target is described. Coprecipitation from strontium sulphate was used to separate the /sup 203/Pb from a solution of the thallium target in sulphuric acid. The SrSO/sub 4/ precipitate was filtered, washed and dissolved in hydrochloric acid, from which /sup 203/Pb was again separated by precipitation on sodium chloride from a strongly acid solution. Advantages of the system are discussed and optimum conditions given.
An improved process is disclosed for reducing the water content of coal containing bound water by releasing at least a portion of the bound water by maintaining the coal at a temperature from about 220/sup 0/ to about 500/sup 0/ F. in the presence of water at a pressure sufficient to maintain at least portion of the water in a liquid phase for a time sufficient to release at least a portion of the bound water wherein the improvement comprises contacting the coal during such treatment with an active material selected from the group consisting of carboxylic organic acids containing up to about 6 carbon atoms, phenol, phenolic acids and inorganic acids.
Locked nucleic acid (LNA) is a nucleic acid analogue containing one or more LNA nucleotide monomers with a bicyclic furanose unit locked in an RNA mimicking sugar conformation. This conformational restriction results in unprecedented hybridization affinity towards complementary single stranded RNA and thus, makes LNA uniquely suited for mimicking RNA structures and sequence specific targeting of RNA in vitro or in vivo. The focus of this paper is on LNAantisense, LNA-modified siRNA (siLNA), and detection and analysis of microRNAs by LNA-modified oligonucleotide probes.
A short-chain neurotoxin Pseudechis australis a (toxin Pa a) was isolated from the venom of an Australian elapid snake Pseudechis australis (king brown snake) by sequential chromatography on CM-cellulose, Sephadex G-50 and CM-cellulose columns. Toxin Pa a has an LD50 (intravenous) value of 76 micrograms/kg body wt. in mice and consists of 62 amino acid residues. The amino acid sequence of Pa a shows considerable homology with those of short-chain neurotoxins of elapid snakes, especially of true sea snakes. PMID:4091794
A proposed inhibitor for steel corrosion in hydrochloric acid consists essentially of 0.5% of an inhibitor called BA-6, 0.25-0.5% of 1-hexynol-3, and about 0.02% of potassium iodide (calculated on the amount of acid). The inhibitor DA-6 is produced by condensing benzylamine with utrotropine. 1-Hexynol-3, secondary alcohol, is obtained from butyraldehyde and acetylene in the presence of caustic potash. The increase of potassium iodide concentration from 0.02-0.1% increases the protective action of the inhibitor. Hexynol, dipropargyl ester, and potassium iodide must be introduced in HC1 before injection of the latter into the well.
In this research a sol-gel auto-combustion route has been proposed to synthesize strontium hexaferrite nanopowder, using metal nitrates, ammonia as pH adjusting agent, n-decyltrimethylammonium bromide as a cationic surfactant and different fuels such as citric acid, glycine, acetylacetone and oxalic acid. The formation temperature of strontium hexaferrite and its crystallite size in presence of different fuels were compared together. The results showed the lowest formation temperature as well as the smallest crystallite size in the presence of citric acid as 900degreeC and 37.3nm respectively.
SiSiC is one of selected materials for the thermal chemical hydrogen production IS (Iodine-Sulfur) process at JAERI. SiSiC was tested in boiling sulfuric acid for 1000 hours. The obtained results showed the following facts. The transverse strength was not changed by sulfuric corrosion, high temperature oxidation and oxidation. Silica scale formed on SiSiC by sulfate corrosion and high temperature oxidation had corrosion resistance in boiling sulfuric acid. Bilayer structure of silica scale produced by high temperature oxidation was not affected by sulfate corrosion. (S.Y.).
This patent describes an aqueous clay containing drilling fluid having present in an amount sufficient to reduce fluid loss of the drilling fluid, a copolymer of (1) from about 80% to about 98% by weight of acrylic acid and (2) from about 2% to about 20% by weight of itaconic acid. The copolymer has a weight average molecular weight of between about 50,000 to about 1,000,000, being in its free acid or partially or completely neutralized salt form and being at least water dispersible.
Purpose - The purpose of this paper is to evaluate the corrosion inhibition potential of mangrove (Rhizopora apiculata) tannin in hydrochloric acid medium on copper with the view of developing a natural corrosion inhibitor. Design/methodology/approach - The mangrove tannin was extracted from the mangrove bark and its anticorrosion potential was studied by weight loss, electrochemical and scanning electron microscopy (SEM) analysis. Findings - It has been found that the mangrove tannin effectively inhibits the corrosion on copper metal in hydrochloric acid solution. The results of the electrochemical and weight loss methods showed that the inhibition efficiency of mangrove tannin increases with increasing its concentration. Inhibition is achieved through the adsorption of tannin molecules o...
Magnetic fluids (MFs), prepared by chemical co-precipitation followed by double layer steric and electrostatic (combined) stabilization of magnetite nanoparticles dispersed in water, are presented. Several combinations of surfactants with different chain lengths (lauric acid (LA), myristic acid (MA), oleic acid (OA) and dodecyl-benzene-sulphonic acid (DBS)) were used, such as LA+LA, MA+MA, LA+DBS, MA+DBS, OA+DBS, OA+OA and DBS+DBS. Static light scattering, transmission electron microscopy, small angle neutron scattering, magnetic and magneto-rheological measurements revealed that MFs with MA+MA or LA+LA biocompatible double layer covered magnetite nanoparticles are the most stable colloidal systems among the investigated samples, and thus suitable for biomedical applications.
The present study includes thermal stability of some fatty acids as phase change materials (PCMs). The selected fatty acids were stearic, palmitic, myristic and lauric acid with melting temperatures between 40-63{sup o}C and industrial-grade with 90-95% purity. Latent heat storage capacity and phase transition temperature of the PCMs were determined by Differential Scanning Calorimetry (DSC) technique as a function of after repeated thermal cycles such as 40, 410, 700 and 910. The present work also comprises the investigation of corrosion resistance of some construction materials to the fatty acids over a long period. The containment materials tested were stainless steel (SS 304 L), carbon steel (steel C20), aluminium (Al) and copper (Cu). Gravimetric analysis as mass loss (mg/cm{sup 2}), corrosion rate (mg/day) and a microscopic or metallographic investigation were performed for corrosion tests after ...
A simple method is presented for the separation of lead-203 from copper-backed thallium cyclotron targets. The procedure involves cation-exchange chromatography in hydrochloric acid and hydrochloric acid-acetone mixtures. Further purification involves anion-exchange chromatography in nitric acid-hydrobromic acid mixtures. A cation-exchange column containing 3.0 g of resin can handle as much as 15 g of thallium and 160 mg of copper. An anion-exchange column containing 3.0 g of resin can separate lead from up to 200 mg of thallium and 10 mg of copper. Separations are extremely sharp and less than 0.1 ..mu..g of thallium and less than 0.1 ..mu..g of copper remain in the lead-203 fraction.
A simple method is presented for the separation of lead-203 from copper-backed thallium cyclotron targets. The procedure involves cation-exchange chromatography in hydrochloric acid and hydrochloric acid-acetone mixtures. Further purification involves anion-exchange chromatography in nitric acid-hydrobromic acid mixtures. A cation-exchange column containing 3.0 g of resin can handle as much as 15 g of thallium and 160 mg of copper. An anion-exchange column containing 3.0 g of resin can separate lead from up to 200 mg of thallium and 10 mg of copper. Separations are extremely sharp and less than 0.1 #mu#g of thallium and less than 0.1 #mu#g of copper remain in the lead-203 fraction. (author).
Recent evidence indicates that the evolution of ultrasonic hearing in echolocating bats and cetaceans has involved adaptive amino acid replacements in the cochlear gene prestin. A substantial...Full Text Available
Cuphea, a relatively unknown plant outside the scientific community, might someday provide valuable oils for manufacturing soaps, detergents, surfactants, and lubricants, and may have medical, nutritional and dietetic applications as well. Unique properties of oils found in its seed make cuphea a potentially valuable new crop for the USA. Its seeds contain large quantities of medium-chain fatty acids such as lauric acid, which is used in manufacturing soaps and detergents. Other medium-chain fatty acids in cuphea can be used for clinical treatment of rare human ailments associated with fat absorption. New uses for the fatty acids in the seed may be developed and economic conditions may change, making the crop more or less valuable.
Histamine and the histamine receptors are important regulators of a plethora of biological processes, including immediate hypersensitivity reactions and acid secretion in the stomach. In these...Full Text Available
Culturing human prostate PC-3 cells for 4, 24, or 72 h in the presence of 5,8,11,14-eicosatetraynoic acid (ETYA), an inhibitor of arachidonic acid metabolism and cholesterol biosynthesis, markedly altered the morphology and reduced the number of mitochondria in the treated cells. Using quantitative electron microscopic morphometry, we documented changes in the number, form, area, matrix density, and integrity of the cristae and limiting membranes of mitochondria in cells cultured with ETYA. The inhibition of cholesterol synthesis or the substitution of ETYA for polyunsaturated fatty acids in the inner membrane may participate in the disruption of the mitochondria, which resembles the morphologic sequelae of oxidative stress. If sufficiently extensive, these changes could contribute to the inhibition of cellular proliferation by ETYA.