WorldWideScience
1

Safety culture development at Daya Bay NPP  

International Nuclear Information System (INIS)

From view on Organization Behavior theory, the concept, development and affecting factors of safety culture are introduced. The focuses are on the establishment, development and management practice for safety culture at Daya Bay NPP. A strong safety culture, also demonstrated, has contributed greatly to improving performance at Daya Bay

2001-12-01

2

Nuclear safety culture star-class assessment system based BP neural network  

International Nuclear Information System (INIS)

In order to build the safety culture for nuclear power industry, it is important to evaluate the safety culture scientifically. Considering the traits of safety culture in the nuclear power industry, 24 safety culture assessment indexes are established from 4 aspects such as Safety consciousness, Safety attitude, Safety action and Safety actuality by using the SMART criteria. Safety culture star-class assessment criterion is presented and safety culture star-class assessment system is developed by using Visual Basic 6.0 and BP neural network. The system has a better generalization ability, and it can show exactly which phase the safety ...

2007-02-01

3

Legal Analysis of the Korea Radioactive Waste Management Act in the aspect of IAEA Principles  

International Nuclear Information System (INIS)

According to the Principles of Radioactive Waste Management, the IAEA SAFETY SERIES NO-111-F, IAEA declared 9 doctrines. The IAEA advised a country that operates nuclear power plant to adopt the principles. As a member of the IAEA, Korea has also discussed about a unified policy and enacting law for radioactive waste management to follow the doctrines. This study analyzed the recently enacted Korea Radioactive Waste Management Act and verified whether the Act successfully follows the doctrine or not

2009-05-01

4

Resolving conflicting safety cultures  

International Nuclear Information System (INIS)

Several nuclear power plant sites have been wounded in the crossfire between two distinct corporate cultures. The traditional utility culture lies on one side and that of the nuclear navy on the other. The two corporate cultures lead to different perceptions of open-quotes safety culture.close quotes This clash of safety cultures obscures a very important point about nuclear plant operations: Safety depends on organizational learning. Organizational learning provides the foundation for a perception of safety culture that transcends the conflict between utility and nuclear navy cultures. Corporate culture may be defined as the knowledge, attitudes, and beliefs shared by employees of a given company. Safety ...

1993-06-20

5

Second international symposium on nuclear power plant life management. Book of extended synopses  

International Nuclear Information System (INIS)

The world's fleet of nuclear power plants is, on average, more than 20 years old. Even though the design life of a nuclear power plant is typically 30-40 years, it is quite feasible that many plants will be able to operate in excess of their design lives, provided that nuclear power plant engineers demonstrate by analysis, trending, equipment and system upgrades, increased vigilance, testing and ageing management that the plant will operate safely. In the operation of nuclear power plants, safety should be always the prime consideration. Plant operators and regulators must always ensure that plant safety is maintained, and where possible enhanced, during a plant's operating lifetime. Nuclear power plant life management (PLiM) has gained increased attention over the past decade, and effective ageing management of systems, structures and components (SSCs) is a key element in PLiM for the safe and reliable long term operation of nuclear power ...

2007-10-15

6

A study to develop the domestic functional requirements of the specific safety systems of CANDU  

Energy Technology Data Exchange (ETDEWEB)

The present research has been made to develop and review critically the functional requirements of the specific safety systems of CANDU such as SDS-1, SDS2, ECCS, and containment. Based on R documents for this, a systematic study was made to develop the domestic regulation statements. Also, the conventional laws are carefully reviewed to see the compatibility to CANDU. Also, the safety assessment method for CANDU was studied by reviewing C documents and recommendation of IAEA. Through the present works, the vague policy in the CANDU safety regulation is cleaning up in a systematic form and a new frame to measure the objective risk of nuclear power plants was developed.

2003-03-15

7

A study to develop the domestic functional requirements of the specific safety systems of CANDU  

Energy Technology Data Exchange (ETDEWEB)

The present research has been made to develop and review critically the functional requirements of the specific safety systems of CANDU such as SOS-1, SOS-2, ECCS and containment. Based on R documents for this, a systematic study was made to develop the domestic regulation statements. Also, the conventional laws are carefully reviewed to see the compatibility to CANDU. Also, the safety assessment method for CANDU was studied by reviewing C documents and recommendation of IAEA. Through the present works, the vague policy in the CANDU safety regulation is cleaning up in a systematic form and a new frame to measure the objective risk of nuclear power plants was developed.

2001-03-15

8

A structured approach to the assessment of the quality culture in nuclear installation  

International Nuclear Information System (INIS)

INSAG has emphasized that safety culture has two general components: the organizational framework and the attitude of the staff. To develop a structured approach to the assessment of safety culture, we propose that the highly formalized nature of nuclear power plant organizations be exploited. The prime coordinating mechanism of NPP organizations is the standardization of work processes, where a work process is defined as a standardized sequence of tasks designed to achieve a specific goal (an example is the maintenance work process). The predictable nature of work processes is exploited by the Work Process Analysis Model (WPAM) to conduct a systematic analysis that identifies the desirable characteristics of work processes and develops performance measures for their strengths and weaknesses. These can provide a set of tangible characteristics of a good safety ...

1995-04-01

9

Grading of quality assurance requirements  

International Nuclear Information System (INIS)

The present Manual provides guidance and illustrative examples for applying a method by which graded quality assurance requirements may be determined and adapted to the items and services of a nuclear power plant in conformance with the requirements of the IAEA Nuclear Safety Standards (NUSS) Code and Safety Guides on quality assurance. The Manual replaces the previous publication IAEA-TECDOC-303 on the same subject. Various methods of grading quality assurance are available in a number of Member States. During the development of the present Manual it was not considered practical to attempt to resolve the differences between those methods and it was preferred to identify and benefit from the good practices available in all the methods. The method presented in this Manual deals with the aspects of management, documentation, control, verification and administration which affect quality. 1 fig., 4 tabs.

10

Man-made disasters: A cross-national analysis  

British Library Electronic Table of Contents (United Kingdom)

This research investigates the impact of national culture and several institutional factors on the safety performance of society and establishes statistically significant relationships between those variables. As expected, the research results reveal that some cultural variables such as uncertainty avoidance, gender orientation and institutional variables such as the degree of law avoidance can directly influence the safety performance of the society. The findings also support the inverted u-curve (Safety Kuznet curve) hypothesis indicating even if we expect a negative trend at the beginning stage of industrialization, we can expect a positive trend in safety performance as their income level continues to improve beyond a certain point.

2011-01-01

11

Nuclear forensics support. Reference manual  

International Nuclear Information System (INIS)

Illicit trafficking of nuclear and other radioactive material has been an issue of concern since the first seizures in the early 1990s. By the end of 2004 Member States had confirmed 540 cases, while about another 500 remain unconfirmed. Most of the confirmed cases have a criminal dimension, even if they were not for known terrorist purposes. The attacks of September 2001 in the USA dramatically emphasized the requirement for the enhanced control and security of nuclear and other radioactive material. In response to a resolution by the IAEA General Conference in September 2002 the IAEA has adopted an integrated approach to protection against nuclear terrorism. This brings together IAEA activities concerned with the physical protection of nuclear material and nuclear installations, nuclear material accountancy, detection and response to illicit nuclear trafficking, the security and safety of radioactive ...

12

The Importance of Building and Enhancing Worldwide Industry Cooperation in the Areas of Radiological Protection, Waste Management and Decommissioning  

International Nuclear Information System (INIS)

The slow or stagnant rate of nuclear power generation development in many developed countries over the last two decades has resulted in a significant shortage in the population of mid-career nuclear industry professionals. This shortage is even more pronounced in some specific areas of expertise such as radiological protection, waste management and decommissioning. This situation has occurred at a time when the renaissance of nuclear power and the globalization of the nuclear industry are steadily gaining momentum and when the industry's involvement in international and national debates in these three fields of expertise (and the industry's impact on these debates) is of vital importance. This paper presents the World Nuclear Association (WNA) approach to building and enhancing worldwide industry cooperation in radiological protection, waste management and decommissioning, which is manifested through the activities of the two WNA working groups on radiological protection (RPWG) and on ...

13

Monitoring processes and measuring the effectiveness of the management system  

International Nuclear Information System (INIS)

This document presents the way which the 8th principle of the quality management system 'Process approach' is applied, the principle that is identified and used by international standard ISO 9000. In order to understand the evolution of the management system requirements, as used today in different activities namely, industry, services, and nuclear activities, the authors present an evolution of the quality concept and its traceability to different standards, applicable in time. There are described the requirements of ISO 9001 standard, that represents the most widely spread model for modern organization management and the IAEA concerns related to integration of the above standard requirements into the most recent safety IAEA standard 'The Management System for facilities and activities'. The IAEA Safety Standard GS-R-3 describes a management model considering both the evolution of ...

2009-10-12

14

Different aspects of safety in Nuclear Fuel Plant at Pitesti, Romania  

International Nuclear Information System (INIS)

Nuclear Fuel Plant (FCN) is a facility that produces fuel bundles of CANDU-6 type for the CANDU nuclear power plant. Only natural and depleted uranium in bulk and itemized form are present as nuclear materials in this facility. Uranium and wastes from the plant are handled, processed, treated and stored throughout the entire facility. The nuclear materials with natural and depleted uranium are entirely under nuclear safeguards. The amount of uranium present in the plant in different forms and activities together with zircaloy, beryllium and other hazardous substances, wastes, explosive materials at high temperatures, etc. lead to special measures undertaken by Nuclear Safety Department (DNS) to ensure nuclear safety. Different aspects of safety are continuously monitored in the plant: operational safety, industrial safety, radiological safety, labour ...

2009-10-12

15

ORNL results for Test Case 1 of the International Atomic Energy Agency`s research program on the safety assessment of Near-Surface Radioactive Waste Disposal Facilities  

Energy Technology Data Exchange (ETDEWEB)

The International Atomic Energy Agency (IAEA) started the Coordinated Research Program entitled ```The Safety Assessment of Near-Surface Radioactive Waste Disposal Facilities.`` The program is aimed at improving the confidence in the modeling results for safety assessments of waste disposal facilities. The program has been given the acronym NSARS (Near-Surface Radioactive Waste Disposal Safety Assessment Reliability Study) for ease of reference. The purpose of this report is to present the ORNL modeling results for the first test case (i.e., Test Case 1) of the IAEA NSARS program. Test Case 1 is based on near-surface disposal of radionuclides that are subsequently leached to a saturated-sand aquifer. Exposure to radionuclides results from use of a well screened in the aquifer and from intrusion into the repository. Two repository concepts were defined in Test Case 1: a simple earth ...

1993-07-01

16

Quantification of radionuclide transfer in terrestrial and freshwater environments for radiological assessments  

International Nuclear Information System (INIS)

For more than thirty years, the IAEA has published a set of documents aimed at the limitation of the radiation exposure of the population from various nuclear activities. In particular, in 1994 the IAEA published Technical Reports Series No. 364, Handbook of Parameter Values for the Prediction of Radionuclide Transfer in Temperate Environments. Over the years, it has proved to be a valuable reference for radioecologists, modellers and authorities in Member States, and has been quoted in numerous impact assessments. Technical Reports Series No. 364 was based on a review of available data up to the end of 1992. However, a number of high quality critical reviews have been produced in recent years for some of the transfer parameter values which merit consideration. Thus, it was assumed that there is sufficient new information available to warrant reconsideration of a significant proportion of the values given in Technical Reports Series No. 364 and ...

1993-04-05

17

A study for good regulation of the CANDU's in Korea  

Energy Technology Data Exchange (ETDEWEB)

The objective of project is to derive the policy recommendations to improve the efficiency of CANDU plants regulation. These policy recommendations will eventually contribute to the upgrading of Korean nuclear regulatory system and safety enhancement. During the second phase of this 2 years study, following research activities were done. Review the technical basis and framework of the new Canadian Regulation System and IAEA. Analysis on the interview of Wolsung operation staffs to identify important safety issues and regulation problems experienced at operation. Providing a plan of CANDU regulation system enhancement program.

2002-03-15

18

Report of the ASSET (Assessment of Safety Significant Events Team) mission to the Zaporozhe nuclear power plant in Ukraine 13-24 June 1994 Division of Nuclear Safety. Root cause analysis of operational events with a view to enhancing the prevention of incidents  

International Nuclear Information System (INIS)

The IAEA Assessment of Safety Significant Events Team (ASSET) report presents the results of an ASSET team's assessment of their investigation of the effectiveness of the plant for prevention of incidents since 1990 at Zaporozhe nuclear power plant. The results, conclusions and suggestions presented herein reflect the views of the ASSET experts. They are provided for consideration by the responsible authorities in Ukraine. The ASSET team's views presented in this report are based on visits to the plant, on review of documentation made available by the operating organization and on discussions with utility personnel. The report is intended to enhance operational safety at Zaporozhe by proposing improvements to the policy for the prevention of incidents at the plant. The report includes, as a usual practice, the official response of the operating organization as well as of the regulatory body to the ASSET recommendations. ...

2003-11-01

19

The Joint Convention on the Safety of Spent fuel Management and on the safety of Radioactive Waste Management: A UK Regulator's Perspective  

International Nuclear Information System (INIS)

The UK fully supports the objective of the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management to achieve and maintain a high level of safety worldwide in spent fuel and radioactive waste management, through the enhancement of national measures and international co-operation, including where appropriate, safety-related co-operation. The UK's Health and Safety Executive, through its Nuclear Safety Directorate (NSD), has been committed to the Convention since the initial negotiations to set up the Convention and provided the president of the first review meeting in 2003. It would be wrong of any nation to believe that they have all the best solutions to managing spent fuel and radioactive waste. The process of compiling reports for the Convention review meetings provides a structured process through which every ...

20

Sequential chemical treatment of radium species in TENORM waste sludge produced from oil and natural gas production  

British Library Electronic Table of Contents (United Kingdom)

This paper is dedicated to the treatment of sludge occurring in frame of the Egyptian produced from oil and gas production. The activity levels of three radium isotopes: Ra-226 (of U-series), Ra-228 and Ra-224 (of Th-series) in the solid TENORM waste (sludge) were first evaluated and followed by a sequential treatment for all radium species (fractions) presented in TENORM. The sequential treatment was carried out based on two approaches `A' and `B' using different chemical solutions. The results obtained indicate that the activity levels of all radium isotopes (Ra-226, Ra-228 and Ra-224) of the environmental interest in the TENORM waste sludge were elevated with regard to exemption levels established by IAEA [International Atomic Energy Agency (IAEA), International basic safety standards f...

2009-01-01

21

Safety performance indicators. Topical issues paper no. 5  

International Nuclear Information System (INIS)

Since its creation the nuclear industry has been struggling with the question of how safe is safe enough. Safety is a common goal to all involved in the design, operation and regulation of a nuclear installation. As a concept safety is not easy to define. However, there is a general understanding of what attributes a nuclear power plant should have in order to operate safely. The challenge lies in measuring the attributes. The new competitive open electricity market, in many countries throughout the world, is increasing the economic pressure on operators to lower operating costs without jeopardizing safety. Challenges are occurring at a rate that is unprecedented in the nuclear industry: competitiveness; downsizing; ageing; policy changes; reorganization; restructuring; mergers; globalization; and takeovers demand increasing attention to the management of safety. There are various means to measure ...

2001-09-03

22

Status and trends of nuclear technologies - Report of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO). Additional information (Companion CD-ROM)  

International Nuclear Information System (INIS)

The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was launched in the year 2000, based on a resolution by the IAEA General Conference (GC(44)/RES/21). INPRO intends to help to ensure that nuclear energy is available in the 21st century in a sustainable manner, and seeks to bring together all interested Member States, both technology holders and technology users, to consider, jointly, actions to achieve desired innovations. INPRO is taking care of the specific needs of developing countries. This IAEA publication is part of Phase 1 of INPRO. It intends to provide an overview on history, present situation and future perspectives of nuclear fuel cycle technologies. While this overview focuses on technical issues, nevertheless, the aspects of economics, environment, and safety and proliferation resistance are important background issues for this study. After a brief description about the INPRO ...

1991-01-01

23

Indicators of safety culture - selection and utilization of leading safety performance indicators  

International Nuclear Information System (INIS)

Safety indicators play a role in providing information on organizational performance, motivating people to work on safety and increasing organizational potential for safety. The aim of this report is to provide an overview on leading safety indicators in the domain of nuclear safety. The report explains the distinction between lead and lag indicators and proposes a framework of three types of safety performance indicators - feedback, monitor and drive indicators. Finally the report provides guidance for nuclear energy organizations for selecting and interpreting safety indicators. It proposes the use of safety culture as a leading safety performance indicator and offers an example list of potential indicators in all three categories. The report concludes that monitor and drive ...

2010-05-01

24

SSAC at Your Service: Promoting Co-operation Between IAEA and Finnish SSAC for Safeguards Implementation (Within the EU)  

International Nuclear Information System (INIS)

As the nuclear world is changing, the non-proliferation and safeguard systems have to change along the global development. Nuclear security as well as safety must be involved in all phases. Thus, modernization of thinking is a must. State system of accounting for and control of nuclear material (SSAC) is a basis, but now it is time to move ahead. Safeguards is not any more only to verify the declared nuclear materials but it is to inform the international safeguards society transparently but confidentially about the nuclear fuel cycle related activities and trade, and to confirm that there are no undeclared activities related to the nuclear fuel cycle in the states. Only strong SSAC with enhanced capabilities, activities and rights can meet the demand. The proliferation of nuclear weapons is a threat that also urges cooperation at all levels. International, regional and state systems must work closely together, and there is need and space for everyone. State ...

2010-11-01

25

CANDU licensing in Korea : status review and future requirements  

International Nuclear Information System (INIS)

The licensing status and procedures, regulatory framework, and current safety issues of CANDU type reactors, Wolsong units 2, 3 and 4 are examined. Licensing difficulties and lessons learned during the safety review of Wolsong 2, 3 and 4 and future requirements are also summarized. The review was conducted, not only to confirm the design adequacy with respect to the domestic atomic laws and regulatory requirements of the vendor country, Canada, but also to reflect into the design the lessons learned from the regulatory experiences of operating Wolsong I to enhance the safety as high as practically possible. Safety issues observed during the licensing review, such as containment integrity, fuel channel integrity, etc., are summarized. Several efforts have been conducted to harmonize the Canadian regulations with the Korean ones by establishing domestic regulatory positions and guidelines. For example, ...

1998-05-03

26

Integrated Safeguards proposal for Finland. Final report on Task FIN C 1264 of the Finnish Support Programme to IAEA Safeguards  

Energy Technology Data Exchange (ETDEWEB)

The IAEA has requested several member states to present their proposal of the application of the Integrated Safeguards (IS) system in their nuclear facilities. This report contains a IS proposal for Finland prepared under the Task FIN C 1264 of The Finnish Support Programme to IAEA Safeguards. The comprehensive safeguards system of the International Atomic Energy Agency (IAEA) has been one of the main tools in the fight against nuclear proliferation since the entry-into-force of the Nuclear Non-proliferation Treaty three decades ago. In the 1990s some of the inherent weaknesses of this so-called traditional safeguards system were revealed first in Iraq and then in North Korea. Therefore, the member states of the LAEA decided to give the Agency additional legal authority in order to make its control system more effective as well as more efficient than before. This was accomplished by the approval of the so-called Model ...

2000-08-01

27

Status of non-electric nuclear heat applications: Technology and safety  

International Nuclear Information System (INIS)

Nuclear energy plays an important role in electricity generation, producing 16% of the world's electricity at the beginning of 1999. It has proven to be safe, reliable, economical and has only a minimal impact on the environment. Most of the world's energy consumption, however, is in the form of heat. The market potential for nuclear heat was recognized early. Some of the first reactors were used for heat supply, e.g. Calder Hall (United Kingdom), Obninsk (Russian Federation), and Agesta (Sweden). Now, over 60 reactors are supplying heat for district heating, industrial processes and seawater desalination. But the nuclear option could be better deployed if it would provide a larger share of the heat market. In particular, seawater desalination using nuclear heat is of increasing interest to some IAEA Member States. In consideration of the growing experience being accumulated, the IAEA periodically reviews the progress and new developments in ...

28

The IAEA Code of Practice on quality assurance, and quality assurance requirements and practices in Member States  

International Nuclear Information System (INIS)

The IAEA Code of Practice on Quality Assurance for Safety in Nuclear Power Plants and the corresponding Safety Guides are reviewed and compared with quality assurance (QA) practices in the IAEA Member States. The QA requirements stipulated by the Code place on the nuclear power plant owner the responsibility to establish an overall QA programme for the plant. In selecting the QA programme level for specific activities, the Code allows of a flexible approach but does not specify gradation in programme requirements. The Code is placing the burden of quality-achieving and quality-assuring functions on the task-performing organizations, namely the designers, manufacturers, constructors and plant operators. The plant owner provides for the management of the overall QA programme, surveillance of activities and verifications of the effectiveness of the constituent programmes of all project participants through ...

29

Effects of cell culture conditions on antibody N-linked glycosylation-what affects high mannose 5 glycoform  

British Library Electronic Table of Contents (United Kingdom)

Abstract The glycosylation profile of therapeutic antibodies is routinely analyzed throughout development to monitor the impact of process parameters and to ensure consistency, efficacy, and safety for clinical and commercial batches of therapeutic products. In this study, unusually high levels of the mannose-5 (Man5) glycoform were observed during the early development of a therapeutic antibody produced from a Chinese hamster ovary (CHO) cell line, model cell line A. Follow up studies indicated that the antibody Man5 level was increased throughout the course of cell culture production as a result of increasing cell culture medium osmolality levels and extending culture duration. With model cell line A, Man5 glycosylation increased more than twofold from 12% to 28% in the fed-batch process...

2011-01-01

30

Lessons learned from accidents investigations  

International Nuclear Information System (INIS)

Accidents from three main practices: medical applications, industrial radiography and industrial irradiators are used to illustrate some common causes of accidents and the main lessons to be learned. A brief description of some of these accidents is given. Lessons learned from the described accidents are approached by subjects covering: safety culture, quality assurance, human factors, good engineering practice, defence in depth, security of sources, safety assessment and monitoring and verification compliance. (author)

1997-10-26

31

The Nuclear Safety Convention and French law  

Energy Technology Data Exchange (ETDEWEB)

French law should not be very affected when the NSC enters into force in France. This results from the fact that French law has already achieved most of the `work` to be done in the field of safety of nuclear installations as it integrated the concept of `safety culture` (i.e. high level of safety for nuclear installations) which is, actually, the main objective of this convention. The elaboration of this convention on safety of nuclear power plants took approximately 3 years. The success (i.e. adoption of the draft text by the Diplomatic Conference) was made possible because of the large technical consensus existing among experts in that field. This means that if we intend to do the same in the field of radioactive waste management, we have to get first a similar consensus on fundamental adequate principles. (orig./HP)

1995-12-31

32

Proceedings of a specialist meeting on regulatory approaches for the control of environmental residues containing naturally occurring radioactive material. Working material  

International Nuclear Information System (INIS)

Naturally occurring radionuclides are present in most material. The most common naturally occurring radionuclides in material are those of the uranium and thorium series and potassium-40. This material is commonly referred to as Naturally Occurring Radioactive Material (NORM). In some material the levels of naturally occurring radionuclides are significantly higher, to the extent that regulatory control may be required for radiation protection purposes. Regulation of NORM presents a range of new challenges for both regulators and operators. Unlike more traditional industries dealing with radionuclides, NORM industries have generally not had any radiological oversight and, for example, are not equipped for radiological monitoring. Some consumer goods containing NORM, which have not traditionally been considered as a radiological problem (such as some fertilizers), may require regulation and this may have social and economic consequences. The transport and disposal of NORM are also a ...

2002-09-23

33

Safety evaluation of Propionibacterium freudenreichii ET-3 culture.  

Science.gov (United States)

Propionibacterium freudenreichii ET-3 culture, a cell-free product of whey fermentation using P. freudenreichii ET-3 (7025), has been shown to promote the growth of Bifidobacteria through the action of 1,4-dihydroxy-2-naphthoic acid (DHNA), and therefore, has potential use in the food and supplement industries. Although currently used as a food ingredient in Japan, the safety of this novel ingredient has not been previously evaluated through traditional toxicity testing. Therefore, here we report the results of standard toxicological testing performed on P. freudenreichii ET-3 culture. In a 4-week oral toxicity study, administration of 6000mg/kg body weight/day P. freudenreichii ET-3 culture was without compound-related adverse effects on clinical signs, body weights, food consumption, ophthalmology, hematology, clinical chemistry, urinalysis, organ weights, and gross and microscopic findings in male ...

2011-03-22

34

CANDU 9 - the CANDU product to meet customer and regulator requirements now and in the future  

Energy Technology Data Exchange (ETDEWEB)

CANDU reactors developed under Canadian licensing regulations that placed the primary responsibility for safety on the licensee. The Atomic Energy Control Board (AECB), Canada's nuclear regulatory agency, state in their regulations what is expected in terms of safety performance so that designers are free to propose the best means of meeting this performance. This goal-oriented approach, besides encouraging innovation, allowed CANDU to be licensed in other jurisdictions. The latest design - the large, single unit, CANDU 9 - explicitly incorporates licensability in Canada through a formal AECB review of the design; lessons learned from licensing CANDU 6 in Asian countries, particularly with Wolsong 2, 3 and 4 in Korea, and more recently with Qinshan in China; utility requirements for modem evolutionary plants; and emerging international standards for safety, sponsored or issued by the IAEA. By ...

1998-07-01

35

CANDU 9 - the CANDU product to meet customer and regulator requirements now and in the future  

International Nuclear Information System (INIS)

CANDU reactors developed under Canadian licensing regulations that placed the primary responsibility for safety on the licensee. The Atomic Energy Control Board (AECB), Canada's nuclear regulatory agency, state in their regulations what is expected in terms of safety performance so that designers are free to propose the best means of meeting this performance. This goal-oriented approach, besides encouraging innovation, allowed CANDU to be licensed in other jurisdictions. The latest design - the large, single unit, CANDU 9 - explicitly incorporates licensability in Canada through a formal AECB review of the design; lessons learned from licensing CANDU 6 in Asian countries, particularly with Wolsong 2, 3 and 4 in Korea, and more recently with Qinshan in China; utility requirements for modem evolutionary plants; and emerging international standards for safety, sponsored or issued by the IAEA. By combining ...

1998-05-03

36

Report of the technical committee meeting 1997 annual workshop on ASSET experience and feedback  

International Nuclear Information System (INIS)

Papers and presentations were made by all participating countries and provided a wide range of perspectives on the use of the ASSET methodology. Generally, the views expressed were positive, however, there were comments on areas were the service could be improved or enhanced. The workshop was divided into three task groups to analyze the self-assessments conducted at Krsko NPP, Slovenia; Dukovany NPP, Czech Republic; and Balakovo NPP, Russian Federation. In addition, they were asked to comment on the recommendations on the ASSET service made by the Consultants' Meeting of 26-30 August 1996 on ''Performance of the IAEA programme on Operational Safety Services''. A presentation was made by Mr. B. Thomas to remind delegates of the ASSET methodologies, and Mr. V. Sivokon demonstrated the latest developments of computer software available for assisting in the plant Self-Assessment process. Refs, figs, tabs.

1997-06-24

38

Safe ageing management of nuclear power plants: An European synthesis  

International Nuclear Information System (INIS)

Ageing of nuclear power plants means evolution of material or equipment properties on one side, and evolution of personnel skill and procedure adequacy on the other side, both of which, after a certain time, may not be compatible with the required safety provisions, or with an economic operation of the plant. Repair or replacement of components, as well as change in service conditions for a better compatibility with component reduced capabilities can be used to mitigate ageing effects. The paper summarises the results of a study conducted in this field with the support of the European Commission. It presents: the synthesis of the work done under international auspices, and in the European context; the comparison of ageing management approaches used in several European countries with international recommendations; the summary of the various potential phenomena and their governing parameters, the methods of in-service ageing identification and possible mitigation ...

2002-11-04

39

Safety and immunogenicity of ERA strain of rabies virus propagated in a BHK-21 cell line.  

UK PubMed Central (United Kingdom)

The ERA strain of rabies virus was propagated in a baby hamster kidney cell line (BHK-21/C13). The viral titer was 10(1.8) tissue culture infective doses (TCID) higher than that of commercial ERA vaccine....Full Text Available

1989-10-01

40

Sequential chemical treatment of radium species in TENORM waste sludge produced from oil and natural gas production.  

Science.gov (United States)

This paper is dedicated to the treatment of sludge occurring in frame of the Egyptian produced from oil and gas production. The activity levels of three radium isotopes: Ra-226 (of U-series), Ra-228 and Ra-224 (of Th-series) in the solid TENORM waste (sludge) were first evaluated and followed by a sequential treatment for all radium species (fractions) presented in TENORM. The sequential treatment was carried out based on two approaches 'A' and 'B' using different chemical solutions. The results obtained indicate that the activity levels of all radium isotopes (Ra-226, Ra-228 and Ra-224) of the environmental interest in the TENORM waste sludge were elevated with regard to exemption levels established by IAEA [International Atomic Energy Agency (IAEA), International basic safety standards for the protection against ionizing radiation and for the safety of radiation sources. GOV/2715/Vienna, 1994]. Each ...

2008-04-18

41

Sequential chemical treatment of radium species in TENORM waste sludge produced from oil and natural gas production  

Energy Technology Data Exchange (ETDEWEB)

This paper is dedicated to the treatment of sludge occurring in frame of the Egyptian produced from oil and gas production. The activity levels of three radium isotopes: Ra-226 (of U-series), Ra-228 and Ra-224 (of Th-series) in the solid TENORM waste (sludge) were first evaluated and followed by a sequential treatment for all radium species (fractions) presented in TENORM. The sequential treatment was carried out based on two approaches 'A' and 'B' using different chemical solutions. The results obtained indicate that the activity levels of all radium isotopes (Ra-226, Ra-228 and Ra-224) of the environmental interest in the TENORM waste sludge were elevated with regard to exemption levels established by IAEA [International Atomic Energy Agency (IAEA), International basic safety standards for the protection against ionizing radiation and for the safety of radiation ...

2009-01-30

42

Roles of the operator and the safety services in nuclear power plant quality assurance  

International Nuclear Information System (INIS)

With regard to the operation of nuclear power plants, Electricite de France formally recognized in 1973 that it was necessary for safety reasons and economically acceptable to adopt organizational principles of quality assurance that would be applicable both to its own activities and to those of its suppliers. Generally speaking, the form and spirit of the quality assurance programme chosen is based largely on the Code of Practice No. 50-C-QA. In particular, the programme focuses on the flexible character of quality assurance requirements and stresses that in the final analysis product quality depends above all on those to whom the project has been assigned, because it is they who are responsible for meeting the quality objectives set. Ten years of experience with the suppliers of Electricite de France has shown that these suppliers, after some initial difficulty, have been able to adapt the application of quality assurance so as to achieve satisfactory quality as ...

43

International Atomic Energy Agency publications. Publications catalogue 2006 including full details of publications published in 2004-2005 and forthcoming in 2006 and a stocklist of publications published in 2002-2003  

International Nuclear Information System (INIS)

This Publications Catalogue lists all sales publications of the IAEA published in 2004, 2005 and forthcoming in 2006. Most IAEA publications are issued in English, some are also available in Arabic, Chinese, French, Russian or Spanish. This is indicated at the bottom of the book entry. A complete listing of all IAEA priced publications is available on the IAEA's web site: http://www.iaea.org/books

44

Development of quality assurance requirements as part of the regulatory framework in the United Kingdom  

International Nuclear Information System (INIS)

Within the United Kingdom, the regulatory body having responsibility for the licensing of nuclear installations is the Health and Safety Executive (HSE). The Nuclear Installations Inspectorate (NII) is that part of HSE which administers this function. Discussions on the applicability of quality assurance (QA) to licensed sites began in 1974, and an internal report was published in 1975. In parallel with work going on at the International Atomic Energy Agency (IAEA) to prepare Quality Assurance for Safety in Nuclear Power Plants: A Code of Practice, Safety Series No. 50-C-QA, NII published a second report in 1978 entitled A Guide to the Quality Assurance Programme for Nuclear Power Plants. In 1980, the construction of advanced gas cooled reactors at Heysham 2 and at Torness was licensed, and a condition was attached to the licences requiring the licensees to submit their QA arrangements to the NII for ...

1988-11-07

45

Concepts in radiation protection  

International Nuclear Information System (INIS)

This monograph provides basic notions and principles in dosimetry and radiation protection in compliance with two fundamental works: IAEA Safety Series No.115 - International Basic Safety Standards for Protection against Ionizing Radiation and for the Safety of Radiation Sources - and Publication no. 60 of International Commission on Radiological Protection. After the review of quantities and units necessary in radiation protection, the book presents the new values of dose limits as well as the values of 'radiation weighting factor', 'tissue weighting factor' and 'conversion factor intake-dose' (committed effective dose per unit intake) by ingestion and inhalation for 30 most important radionuclides. The new values of dose limits, lower than the old values, are a challenge for the radiation protection, especially of the 'public' where the dose limit diminished by a factor of five relative to the earlier ...

1996-01-01

46

Treatment for dismantled radioactive solid waste from the TRIGA Mark-2 and 3  

Energy Technology Data Exchange (ETDEWEB)

Radioactive wastes are generally classified into 3 type depending on their physical property: liquid, solid and gaseous type. State-of -the art concerning liquid waste treatment has already been published; KAERI/TR-1315/99. Solid wastes classification package and treatment method will be studied to effectively manage them during the practical decommissioning work. All of the spent fuel produced during the operation of the TRIGA Mark-2 and 3 have been transported to the US last year, 1998, according to the spent fuel management strategy set-up by the US government for the non-proliferation of nuclear energy. Solid wastes are mainly all equipment existing inside of the reactors, activated concrete among the bio-shielded concrete, pipes, pimps, resin filter and it's housings, heat-exchangers, liquid waste storage tanks, to radioactive waste storage treatment facilities and so on. Solid wastes are generally low-level. They are classified according to the national regulation and ...

1999-06-01

47

Management of long term radiological liabilities: Stewardship challenges  

International Nuclear Information System (INIS)

The IAEA attaches great importance to the dissemination of information that can assist Member States with the development, implementation, maintenance and continuous improvement of systems, programmes and activities that support the nuclear fuel cycle and nuclear applications, including management of the legacy of past practices and accidents. In this connection, the IAEA has initiated a comprehensive programme of work covering all aspects of environmental remediation: - Technical and non-technical factors, including costs, that influence environmental remediation strategies and pertinent decision making; - Site characterization techniques and strategies; - Assessment of remediation technologies; - Techniques and strategies for post-remediation compliance monitoring; - Special issues such as the remediation of sites with dispersed radioactive contamination or mixed contamination by hazardous and radioactive substances. Experience in Member ...

2006-01-01

48

Safety, Efficacy, and Performance of Implanted Recycled Cardiac Rhythm Management (CRM) Devices in Underprivileged Patients  

British Library Electronic Table of Contents (United Kingdom)

Introduction: Patients in underdeveloped nations have limited access to life-saving medical technology including cardiac rhythm management (CRM) devices. We evaluated alternative means to provide such technology to this patient population while assessing the safety and efficacy of such a practice. Methods: Patients in the United States with clinical indications for extraction of CRM devices were consented. Antemortem CRM devices were cleaned and sterilized following a protocol established at our institution. Surveillance in vitro cultures were performed for quality assurance. The functional status of pulse generators was tested with a pacing system analyzer to confirm at least 70% battery life. Most generators were transported, in person, to an implanting institution in Nicaragua. Recipien...

2011-01-01

49

A Review of the IAEA Vulnerability Assessment Level Scheme: Applicabiliy to DTRA and DOE Programs in the FSU  

Energy Technology Data Exchange (ETDEWEB)

The International Atomic Energy Agency (IAEA) plans to use the Common Criteria, as the tool for developing graded and measurable evaluation criteria for information technology (IT) in safeguards systems in facilities subject to IAEA inspection. In their draft paper [ITSECSES] the IAEA defines a three-tiered Vulnerability Assessment Level (VAL) scheme. Each increased VAL level (1-3) defines additional and more stringent security and security-related requirements for the system developer, the system evaluator (assessor or authenticator), and for the IAEA. When all parties meet all requirements for a particular VAL level, IAEA has a measurable degree of confidence in the secure and proper operation of an IT system.

2001-12-06

51

Influenza Vaccines  

International Science & Technology Center (ISTC)

Development of the Culture Influenza Vaccine

52

International symposium on nuclear security. Book of extended synopses  

International Nuclear Information System (INIS)

The International Symposium on Nuclear Security took place within a context of international acknowledgement that the threat of nuclear terrorism required dedicated action by the international community, States, industry and others. The Symposium dealt with those issues involved in protecting nuclear and other radioactive material from criminals. It also took place against a backdrop of renewed interest in nuclear technology: increased use of nuclear power, and increased use of radioactive isotopes in medicine and in industry. These are welcome developments, since nuclear energy and technology can indeed contribute to the technological and economic welfare of many countries, without compromising public health or the environment. In this context, security measures should not impede State programmes for peaceful use of nuclear technology. The symposium dealt with (1) the threat of nuclear terrorism and of other nuclear-related criminal acts; (2) international response and cooperation; ...

2003-11-05

53

AIDE: internal dosimetry software.  

Science.gov (United States)

AIDE (Activity and Internal Dose Estimates) is a software for calculating activities in compartments and committed doses due to occupational exposures, and for performing intake and dose estimates using bioassay data. It has been continuously developed and tested for more than 20 years. Its calculation core has been applied in several situations, like performing all dose estimates due to (137)Cs intakes, which occurred during the Goiania accident in 1987; performing quality assurance of the ICRP Task Group on Dose Calculations regarding calculations of activities in compartments and generation of dose coefficients for adults due to intakes by inhalation, ingestion and injection of several radionuclides; and producing the tables of activities in compartments and dose coefficients using the NCRP Wound Model for the NCRP report. It provides several capabilities like performing calculations using modified Human Respiratory Tract Model parameters for the mechanical transport, blood ...

2008-03-12

54

Regulation of red mud from the alumina industry in Australia  

International Nuclear Information System (INIS)

English 2005 p. 52-59 International Atomic Energy Agency (IAEA) Collier,

2002-09-23

55

FENDL multigroup libraries  

International Nuclear Information System (INIS)

Selected neutron reaction nuclear data libraries and photon-atomic interaction cross section libraries for elements of interest to the IAEA's program on Fusion Evaluated Nuclear Data Library (FENDL) have been processed into MATXSR format using the NJOY system on the VAX4000 computer of the IAEA. This document lists the resulting multigroup data libraries. All the multigroup data generated are available cost-free upon request from the IAEA Nuclear Data Section. (author). 9 refs.

56

Applied and fundamental aspects of plant cell, tissue, and organ culture  

CERN Document Server

Applied and fundamental aspects of plant cell, tissue, and organ culture

1977-01-01

58

Annual report on heavy water reactor fuel fabrication  

Energy Technology Data Exchange (ETDEWEB)

The CANDU-type nuclear fuel localization project started in 1981, and mass-production system completed in 1987 through the pilot scale demonstration of fuel manufacturing. Since the completion of the mass-production system, about 24,000 fuel bundles (450 ton-U) had been delivered to Wolsung Nuclear Power Plant by the end of 1992, according to the fuel supply contracts with KEPCO. The superiority of KAERI-made nuclear fuel has been demonstrated by having achieved the highest utilization factor in the world in 1992. In 1993, as contracted, 4,824 fuel bundles well fabricated and delivered to Wolsung Nuclear Power Plant. The process improvement, quality control, safety management, safeguards of nuclear materials and various kinds of audits have also been performed in the course for fuel manufacturing. Especially in 1993, the difficulties of the reduction of participating work-force were overcome by improving the manufacturing techniques, and raising the efficiency of ...

1994-03-01

59

Accident analysis in research reactors  

International Nuclear Information System (INIS)

Full text: Full text: The incomplete understanding of the complex mechanisms connected with the interaction between thermal-hydraulic and neutron kinetics still challenges the design and the operation of nuclear reactors and imposes the adoption of conservatism in the evaluation of safety limits. The recent availability of powerful computer and computational techniques together with the continuing increase in operational experience suggests the revisiting of those areas and the identification of design/operation requirements that can be relaxed. So far, almost all of the safety analyses of research reactors have been performed using conservative computational tools such as channel codes but, nowadays, the application of Best-Estimate (BE) methods constitutes a real necessity. The global aim of the current work is an attempt to apply the best-estimate system thermal-hydraulic code Relap5. For this purpose, the generic IAEA ...

2006-10-15

60

Competency build up, sustained performance enhancement of human resource through effective man power planning, training and proper safety culture and organizational climate  

International Nuclear Information System (INIS)

Human resource competence building and continued enhancement of performance is the most vital input for safe and reliable operations of a Nuclear Power Plant. Integrated planning leading to the decision of timely selection of optimum number of fresh people and deployment of experienced manpower with desired lead time is inevitable to achieve the above objective. For safe and reliable plant operation human performance analysis followed by suggestive measures to improve the same is needed. Corrective or strengthening input may be in terms of training, work environment, motivations, organizational culture and climate, leadership and prevailing environmental force and bio-rhythm of individuals with critical days are to be worked out The adequacy in training and development not only gives safe and reliable plant operations but results in greater employee satisfaction and self esteem as well. As of date, in the present vibrant global scenario, only the organization which ...

2006-11-13

61

Special Nevada report  

Energy Technology Data Exchange (ETDEWEB)

This report is submitted to Congress by the Secretary of the Air Force, the Secretary of the Navy, and the Secretary of the Interior pursuant to Section 6 of the Military Lands Withdrawal Act of 1986. It contains an analysis and evaluation of the effects on public health and safety resulting from DOD and Department of Energy (DOE) military and defense-related uses on withdrawn public lands in the State of Nevada and in airspace overlying the State. This report describes the cumulative impacts of those activities on public and private property in Nevada and on plants, fish and wildlife, cultural, historic, scientific, recreational, wilderness and other resources of the public lands of Nevada. An analysis and evaluation of possible measures to mitigate the cumulative effects of the withdrawal of lands and the use of airspace in Nevada for defense-related purposes was conducted, and those considered practical are listed.

1991-09-23

62

Plan for addressing issues relating to oil shale plant siting  

Energy Technology Data Exchange (ETDEWEB)

The Western Research Institute plan for addressing oil shale plant siting methodology calls for identifying the available resources such as oil shale, water, topography and transportation, and human resources. Restrictions on development are addressed: land ownership, land use, water rights, environment, socioeconomics, culture, health and safety, and other institutional restrictions. Descriptions of the technologies for development of oil shale resources are included. The impacts of oil shale development on the environment, socioeconomic structure, water availability, and other conditions are discussed. Finally, the Western Research Institute plan proposes to integrate these topics to develop a flow chart for oil shale plant siting. Western Research Institute has (1) identified relative topics for shale oil plant siting, (2) surveyed both published and unpublished information, and (3) identified data gaps and research needs. 910 refs., 3 ...

1987-09-01

63

Klickitat Cogeneration Project : Final Environmental Assessment.  

Energy Technology Data Exchange (ETDEWEB)

To meet BPA`s contractual obligation to supply electrical power to its customers, BPA proposes to acquire power generated by Klickitat Cogeneration Project. BPA has prepared an environmental assessment evaluating the proposed project. Based on the EA analysis, BPA`s proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 for the following reasons: (1)it will not have a significant impact land use, upland vegetation, wetlands, water quality, geology, soils, public health and safety, visual quality, historical and cultural resources, recreation and socioeconomics, and (2) impacts to fisheries, wildlife resources, air quality, and noise will be temporary, minor, or sufficiently offset by mitigation. Therefore, the preparation of an environmental impact statement is not required and BPA is issuing this FONSI (Finding of No ...

1994-09-01

64

Cross-Cultural Studies of Personality Traits and their Relevance to Psychiatry  

UK PubMed Central (United Kingdom)

AimsThis article provides a brief review of recent cross-cultural research on personality traits at both individual and culture levels, highlighting the relevance...Full Text Available

2006-01-01

65

Geographic Response Information Network : a new tool to manage community information for oil spill contingency planning and response operations  

Energy Technology Data Exchange (ETDEWEB)

This paper described the Geographic Response Information Network (GRIN) project which was launched to address some of the logistical challenges that often complicate oil spill and emergency response operations. The objective of the project was to develop a computer-based tool for incident logistics to organize maps and data related to oil spills, safety, public relations and basic community resources. In addition to its use for oil spill response planning, the data available can be useful for all-hazards emergency response planning. Early prototypes of the GRIN used PowerPoint slides to organize basic information about coastal communities in Alaska. With time, hyper text markup language (html) was used as the programming format because it can be more readily hyper-linked. Currently, GRIN is organized as a web page with the following 5 categories of information: general, liaison, public information, logistics and safety. There are several ...

2006-07-01

66

The Experience of Cooperation with IAEA new approach for Spent Fuel Transfer Campaign at CANDU Reactors  

Energy Technology Data Exchange (ETDEWEB)

It was agreed that both of the Republic Of Korea (ROK) and the International Atomic Energy Agency (IAEA) cooperate with the new approach using the Unattended Monitoring Systems (UMS), the mailbox declaration and the short notice inspections, which can decrease the agency inspection efforts and operator' s burden. As a result of the positive cooperation of ROK for applying new approach, the IAEA could accomplish a successful implementation of new safeguards approach during last transfer campaigns at Wolsung site. As of the end of Feb. 2007, the IAEA installed the UMS at Wolsung units 2, 3 and 4. The transfer campaigns at Wolsung units 2 and 4 are performing from April, 2007. The IAEA will install the UMS at Wolsung unit 1 by the end of 2007. Then agency will inspect all of transfer campaign at Wolsung units by using new approach with UMS, mailbox declaration and SNI. It is based on the SSAC full ...

2007-07-01

67

The Experience of Cooperation with IAEA new approach for Spent Fuel Transfer Campaign at CANDU Reactors  

International Nuclear Information System (INIS)

It was agreed that both of the Republic Of Korea (ROK) and the International Atomic Energy Agency (IAEA) cooperate with the new approach using the Unattended Monitoring Systems (UMS), the mailbox declaration and the short notice inspections, which can decrease the agency inspection efforts and operator' s burden. As a result of the positive cooperation of ROK for applying new approach, the IAEA could accomplish a successful implementation of new safeguards approach during last transfer campaigns at Wolsung site. As of the end of Feb. 2007, the IAEA installed the UMS at Wolsung units 2, 3 and 4. The transfer campaigns at Wolsung units 2 and 4 are performing from April, 2007. The IAEA will install the UMS at Wolsung unit 1 by the end of 2007. Then agency will inspect all of transfer campaign at Wolsung units by using new approach with UMS, mailbox declaration and SNI. It is based on the SSAC full ...

2007-05-10

68

The U.S. Support Program to IAEA Safeguards - How It Works  

Energy Technology Data Exchange (ETDEWEB)

The U.S. Support Program to International Atomic Energy Agency (IAEA) Safeguards (USSP) was established in 1977 to transfer US technology and expertise to assist the IAEA Department of Safeguards because its limited budget and scope would not allow for R&D activities and the procurement of specialized or customized equipment. Over the years, the USSP and the Department of Safeguards have worked together continuously to develop and improve processes for requesting, selecting, and managing projects that support the Safeguards verification mission. This paper will discuss the main USSP processes for accepting and processing Safeguards requests, and managing and reporting task progress.

2008-07-13

69

Factors Influencing the Tissue Culture and the Agrobacterium tumefaciens-Mediated Transformation of Hybrid Aspen and Poplar Clones  

UK PubMed Central (United Kingdom)

Tissue culture conditions and transformation have been established for both aspen and poplar. The use of previously described culture conditions resulted in shoot tip necrosis in the shoot cultures...Full Text Available

1990-07-01

71

A study on multi-cultural family wives adapting to Korean cuisine and dietary patterns  

UK PubMed Central (United Kingdom)

With the increase in multi-cultural families, Korea is seeing a rapid increase in immigrated housewives, who are closely related to food culture. However, studies for the diet of multi-cultural families,...Full Text Available

2010-10-01

73

The Status of Korea-IAEA Enhanced Cooperation on the Spent Fuel Transfer to Dry Storage in CANDU Reactors  

Energy Technology Data Exchange (ETDEWEB)

Based on the enhanced cooperation between Republic of Korea (ROK) and International Atomic Energy Agency (IAEA), IAEA installed new safeguards equipment (Unattended Monitoring System, UMS) at Wolsung unit 2 on January, 2005. The UMS was utilized in parallel with traditional human surveillance during the transfer campaign of Wolsung unit 2 (7 March - 22 July). Installation of UMS at all Wolsung units will be decided on the basis of the result of this test. The transfer campaign with UMS at Wolsung units 2 and 4 was started from September 1, 2006 at the same time. Implementation of UMS to the transfer campaign in Wolsung site will be considerably reduced the IAEA's inspection effort and burden of operator.

2006-07-01

74

The Status of Korea-IAEA Enhanced Cooperation on the Spent Fuel Transfer to Dry Storage in CANDU Reactors  

International Nuclear Information System (INIS)

Based on the enhanced cooperation between Republic of Korea (ROK) and International Atomic Energy Agency (IAEA), IAEA installed new safeguards equipment (Unattended Monitoring System, UMS) at Wolsung unit 2 on January, 2005. The UMS was utilized in parallel with traditional human surveillance during the transfer campaign of Wolsung unit 2 (7 March - 22 July). Installation of UMS at all Wolsung units will be decided on the basis of the result of this test. The transfer campaign with UMS at Wolsung units 2 and 4 was started from September 1, 2006 at the same time. Implementation of UMS to the transfer campaign in Wolsung site will be considerably reduced the IAEA's inspection effort and burden of operator.

2006-11-02

76

Nuclear Power Reactors in the World. 2009 Ed  

International Nuclear Information System (INIS)

This is the twenty-ninth edition of Reference Data Series No. 2, Nuclear Power Reactors in the World, which is published once per year, and presents the most recent reactor data available to the IAEA. It contains the following summarized information: - General information as of the end of 2008 on power reactors operating or under construction, and shut down; - Performance data on reactors operating in the Agency's Member States, as reported to the IAEA. The IAEA's Power Reactor Information System (PRIS) is a comprehensive data source on nuclear power reactors in the world. It includes specification and performance history data of operating reactors as well as reactors under construction or reactors being decommissioned. PRIS data are collected by the IAEA through the designated national correspondents of Member States

77

University of Central Lancashire - Facilities  

Wastenet

...specialised laboratories for pharmaceutics, tissue culture and molecular biology Excellent Laboratory Facilities Tissue Culture Facilities Molecular Biology Laboratory ...

80

Variations in humanized and defined culture conditions supporting derivation of new human embryonic stem cell lines  

DEFF Research Database (Denmark)

The evolution of "humanized" (i.e., free of animal sourced reagents) and ultimately chemically defined culture systems for human embryo stem cell (hESC) isolation and culture is of importance to improving their efficacy and safety in research and therapeutic applications. This can be achieved by integration of a multitude of individual approaches to replace or eliminate specific animal sourced reagents into a single comprehensive protocol. In the present study our objective was to integrate strategies obviating reliance on some of the most poorly defined and path-critical factors associated with hESC derivation, namely the use of animal immune compliment to isolate embryo inner cell mass, and animal sourced serum products and feeder cells to sustain hESC growth and attachment. As a result we report the derivation of six new hESC lines isolated by outgrowth from whole blastocysts on an extracellular matrix substrate of ...

2006-01-01

81

International workshop on 'in vitro' culture of forest tree species. Colloque international sur la culture 'in vitro' des essences forestieres  

Energy Technology Data Exchange (ETDEWEB)

Some 43 papers were presented in 4 sections: Organ and bud culture of tree species (24 papers); Cell suspension and callus culture of tree species (11); Culture of haploid tissue of tree species and production of wood homozygotes (3); and Isolation, culture and somatic fusion of protoplasts as a means of somatic hybridization and genetic engineering (5).

1983-01-01

82

RAAN Conference. Support of Nuclear Power. Opening talk  

International Nuclear Information System (INIS)

Nuclear power in Romania was initiated on the basis of CANDU reactor type technology, an option found to fulfill the requirements for a sustainable economic development, to support the electric energy demand of the country and to ensure the population and environment protection. The construction of the Cernavoda NPP was heavily based on the Romanian industry participation and basic and applied nuclear research national resources. The experience acquired from Cernavoda NPP Unit 1 will be fructified in the construction of Units 2-5 to be built. The Romanian Ministry of Education and Research implemented a nuclear national program for research and development taking into account the European Union requirements and recommendations, the cooperation with the IAEA - Vienna and the Romanian government policy on short and medium terms in the nuclear field. The research-development program targeted: the reactor physics and nuclear fuel management; the operation ...

2002-09-06

83

International Symposium on Nuclear Energy SIEN 2009. Nuclear Power - A New Challenge  

International Nuclear Information System (INIS)

The SIEN 2009 symposium organized by Romanian Nuclear Energy Association, AREN, in co-operation with Romanian Atomic Forum, ROMATOM, was primarily targeting the expert community involved in developing new nuclear power projects and implementing the National Nuclear Program. The symposium was also open as a discussion and information forum for scientists, engineers, technicians and students interested in scientific and technologic topics of Nuclear Power. It was structured in the following 6 sections: - Nuclear new builds and developments; - Operation, inspection and maintenance; - Increasing nuclear safety features; - Fuel cycle and decommissioning; - Public perception and confidence strengthening; - Environmental management. The symposium began with three plenary lectures dealing with: - Sustainable Nuclear Energy European Technology Platform; - Nuclear new-build; - Current issues of nuclear equipment standardization in Romania. A poster session of 5 presentations ...

2009-10-12

84

Implementation strategies and tools for condition based monitoring at nuclear power plants  

International Nuclear Information System (INIS)

There is now an acute need to optimize maintenance to improve both reliability and competitiveness of nuclear power plant operation. There is an increasing tendency to move from the preventive (time based) maintenance concept to one dependent on plant and component conditions. In this context, various on-line and off-line condition monitoring and diagnostics, nondestructive inspection techniques and surveillance are used. Component selection for condition based maintenance, parameter selection for monitoring condition, evaluation of condition monitoring results are issues influencing the effectiveness of condition based maintenance. All these selections of components and parameters to be monitored, monitoring and diagnostics techniques to be used, acceptance criteria and trending for condition evaluation, and the economic aspect of predictive maintenance and condition monitoring should be incorporated into an integrated, effective condition based maintenance programme, which is part of ...

2009-01-01

85

Criticality calculations of the fixed bed nuclear reactor  

Energy Technology Data Exchange (ETDEWEB)

The Fixed Bed Nuclear Reactor (FBNR) is a small 40 MWe reactor based on the Pressurized Water Reactor (PWR) technology. FBNR is an integrated primary circuit and simple in design. It has the characteristics of being small, modular, proliferation resistant, inherently safe and passively cooled reactor with reduced adverse environmental impact. It utilizes the fuel designed for high temperature reactors operating in a relatively low temperature of PWR environment The 15 mm diameter spherical fuel elements are made of TRISO type microspheres embedded in graphite and cladded by SiC. The coolant flow transfers them from the fuel chamber into the core and become fixed forming a suspended core. Any accident signal will cut off the power to the coolant pump causing a stop in the flow. This results in making the fuel elements fall out of the reactor core by the force of gravity and return into the fuel chamber where they are passively cooled under subcritical condition. Therefore, the ...

2007-07-01

86

Hyaluronate synthesis by synovial villi in organ culture. [Dogs  

Energy Technology Data Exchange (ETDEWEB)

Individual canine synovial villi were used to establish short-term synovial organ cultures. These villi incorporated /sup 3/H-glucosamine into highly-polymerized /sup 3/H-hyaluronic acid (/sup 3/H-HA), which was the only /sup 3/H-glycosaminoglycan identified in the culture medium. Some /sup 3/H-HA, and larger amounts of other /sup 3/H-glycosaminoglycans, were recovered from cultured tissues. Culture medium /sup 3/H-HA content was proportional to the surface area of cultured villi. Organ cultures of nonvillous synovium were compared with villi; nonvillous cultures synthesized less /sup 3/H-HA per mm2 of their synovial intimal surface than villi. These cultures complement cell culture techniques for in vitro studies of synovial lining cell function.

1983-06-01

87

The operating experience for Wolsung Unit 3 commissioning  

International Nuclear Information System (INIS)

This is a slide-based oral presentation given to the COG/IAEA: Fifth technical committee meeting on 'Exchange of operating experience of pressurized heavy water reactors' held in Mangalia, Romania on 7-10 September 1998. Since energization of Wolsung Unit 3 station service transformer on July 12, 1996 a line of initial test program was conducted as follows: 1. ILRT/SIT; 2. Pre-operational and Hot Functional testing with a Light Water and without Fuel in Systems; 3. Load D_2O in Moderator System; 4. Initial fuel loading; 5. Load D_2O in PHT System; 6. Hot Functional Testing with Heavy Water and Fuel in Systems; 7. Criticality and Low Power Physics Testing; 8. Power Ascension Test and, then finally, phase-D test; the plant acceptance test was accomplished after having a Mini-Overhaul to prepare for Commercial Operation. These documents contain not only both overall introduction of commissioning and the first TBN rolling and Synchronization test performed in Hot ...

1998-09-07

88

Secure data communication for safeguards implementation  

International Nuclear Information System (INIS)

Full text: Secure, reliable and cost-effective communications are becoming an increasingly important tool for safeguards verification. This trend began with the initiation of remote monitoring implementation, where secure and cost effective data communications were required both to satisfy the confidentiality requirements of Member States and in order to meet the rigorous data authenticity requirements which allow the International Atomic Energy Agency (IAEA) to draw credible and independent conclusions. In addition, the implementation of additional protocols and integrated safeguards increases the importance of information (obtained in the course of an inspection, visit, complementary access or design information verification) being analyzed and corroborated with other information sources stored at IAEA Headquarters or Regional Offices, often while the inspector is still on-site. This requires the capability of enabling the inspector, wherever ...

2006-10-16

89

Overview of IAEA year 2000 activities in the Department of Safeguards  

International Nuclear Information System (INIS)

The IAEA Department of Safeguards established a project in 1996 for the year 2000 (Y2K) conversion activities. This project covered assessment, conversion and testing of the software applications, instrument evaluation software, embedded systems and Personal Computer (PC) hardware attached to various equipment. Significant progress has been made in converting the applications and instruments to be year 2000 compliant. At the same time Member states have made an effort as well in converting the systems used jointly at the facilities

1999-02-01

90

Korea-IAEA Unattended Safeguards Approach on the Spent Fuel Transfer to Dry Storage in Wolsung NPP  

Energy Technology Data Exchange (ETDEWEB)

The field trial of an unattended monitoring system for SF transfer verification ended in June 2005. The system is aiming to improve the safeguards measures applied during SF transfers and reduce inspection effort currently required by the Operator, NNCA and the IAEA. They were reviewed based on its technical performance and other issues in this paper.

2006-07-01

91

Korea-IAEA Unattended Safeguards Approach on the Spent Fuel Transfer to Dry Storage in Wolsung NPP  

International Nuclear Information System (INIS)

The field trial of an unattended monitoring system for SF transfer verification ended in June 2005. The system is aiming to improve the safeguards measures applied during SF transfers and reduce inspection effort currently required by the Operator, NNCA and the IAEA. They were reviewed based on its technical performance and other issues in this paper.

2006-05-25

92

IAEA Nuclear Security Programme Combating Nuclear Terrorism  

International Nuclear Information System (INIS)

IAEA Plans of activities include, General Conference in September 2001 which reviewed activities relevant to preventing nuclear terrorism and proposed master plan. The Board of Governors approved new Nuclear Security Plan for the next four years. Three activity areas are; - needs assessment, analysis and coordination, prevention and detection and response.

2010-05-10

93

Hungarian experience in using the IAEA planning methodologies  

International Nuclear Information System (INIS)

The Hungarian Power Companies Ltd. has been using the IAEA planning methodologies since 1985 when it acquired the WASP model. Since then this model has been applied on a regular basis to determine the least cost expansion plan of the power generating system of the country. This report describes this experience as well as the application of the WASP model for other types of studies. (author).

1997-09-01

94

Technical support for nuclear regulatory activity and the Italian experience  

International Nuclear Information System (INIS)

Different cases exist in various countries regarding the institutional status, the organization and the technical resources of the Nuclear Regulatory Authority (NRA): there are NRAs having extended internal technical capability and others relying mostly on external technical support. Considering the research and development activities and the very broad range of technical matters on which the regulatory and licensing activity are based, the NRA can not rely only on internal resources, and generally there is the need of technical and scientific support together with enhanced international cooperation. The international cooperation and networking among NRAs, and their Technical Support Organizations (TSO), represents a fundamental way to maintain competence, capability and knowledge. Within the EU member states this is becoming more and more an institutional duty. In providing technical support for regulatory activity, the experience shows, from one side, the importance to have TSO with ...

2007-08-01

95
96

The highs and lows of water level : the vulnerability of coastal communities to water level change : final report on the C-CIARN Coastal Zone workshop  

Energy Technology Data Exchange (ETDEWEB)

The Coastal Zone Sector of the Canadian Climate Impact and Adaptation Research Network (C-CIARN) was established to address concerns regarding climate change in coastal areas. Coastal zones are sensitive to increases in air, sea and ground temperatures as well as to variations in sea level, precipitation, ice thickness, and storm intensity. This report presents the results of a workshop which focused on how coastal communities will be affected by climate induced water level changes, particularly sea-level rise on ocean coasts and decreasing lake levels in the Great Lakes. The workshop addressed issues such as the effects of changing water levels on coastal infrastructure, utilities, community development, and the implications of changing water levels to human safety, cultural resources, tourism, and insurance. The workshop reviewed the current state of understanding on water level fluctuations resulting from climate change. It also identified ...

2004-07-01

97

Practice and experience of radiation protection and optimization (ALARA) management system in Daya Bay NPP during the past 10 years  

International Nuclear Information System (INIS)

With the practice of 10 years safe operation, Daya Bay Nuclear Power Station has established and continuously improved the management system for radiation protection and optimization (ALARA) which contains 3 basic requirements: all workers are trained, all employees are engaged in totally, and work management is implemented for the whole process. At the same time, strong efforts have been made to build the 'infrastructure' as a platform for its effective operation. This article introduces the contents and characteristics of the system and basic experiences of its effective implementation. In order to implement the management system effectively, it is necessary for NPPs to strengthen the responsibility system for radiation protection and the leading role of the radiation protection personnel, especially the role of technical support and supervision during the work with high radiation risk, emphasize the organic combination and actively mutual action with the safe operation management ...

2004-05-01

98

Regulation of Embryo Dormancy by Manipulation of Abscisic Acid in Kernels and Associated Cob Tissue of Zea mays L. Cultured in Vitro1  

UK PubMed Central (United Kingdom)

Sectors of Zea mays cobs, with and without kernels were cultured in vitro in the presence and absence of fluridone. Cultured kernels, cob tissue, and embryos developed...Full Text Available

1989-09-01

99

Mass Culture of Subanguina picridis and Its Bioherbicidal Efficacy on Acroptilon repens  

UK PubMed Central (United Kingdom)

A Russian knapweed (Acroptilon repens) shoot culture system, initiated from shoot tip culture, was used to generate a source of host plant tissue for the rearing of the nematode Subanguina...Full Text Available

1993-03-01

100

Effects of pH, Temperature, and Nutrients on Propionate Degradation by a Methanogenic Enrichment Culture  

UK PubMed Central (United Kingdom)

Enrichment cultures were used to determine the conditions promoting fastest methanogenic propionate degradation and growth by adapting the cultures to various physical and chemical conditions and measuring...Full Text Available

1987-07-01

101

Effects of Protons and HZE Particles on Glutamate Transport in Astrocytes, Neurons and Mixed Cultures  

Science.gov (United States)

... ions. MATERIALS AND METHODS Cell Culture Culture of NT2/D1 cells was carried out as described previously (18, 19). NT2 cells were plated at a density of 2. ... ...

102

Cultural Variation in Vigilance and Precaution Themes.  

Science.gov (United States)

Determine the degree to which different precautionary themes are dominant in various target populations and how these themes are acquired. Assess cultural signals of potential danger: are there different kinds of potential danger in different cultures. Do...

2009-01-01

103

Comprehensive Analysis of Blood Culture Performed at Nine University Hospitals in Korea  

UK PubMed Central (United Kingdom)

BackgroundOptimal blood culture performance is critical for successful diagnosis and treatment of sepsis. To understand the status of blood culture, we investigated several aspects...Full Text Available

2011-04-01

104

Comparison of Indoor Mercury Vapor in Common Areas of Residential Buildings with Outdoor Levels in a Community Where Mercury Is Used for Cultural Purposes  

UK PubMed Central (United Kingdom)

Elemental mercury has been imbued with magical properties for millennia, and various cultures use elemental mercury in a variety of superstitious and cultural practices, raising health concerns for...Full Text Available

2006-01-01

105

IAEA and nuclear forensics  

International Nuclear Information System (INIS)

Nuclear forensics can provide information about the history, intended use and potentially the origin of nuclear or radioactive material. For these reasons, it is an important tool for improving nuclear security and combating illicit trafficking of nuclear and other radioactive materials. The IAEA is currently working on enhancing knowledge, techniques, procedures and cooperation in the field of nuclear forensics. Some of the work currently being undertaken by the IAEA includes the development of a five day training workshop on basic methods for radiological crime scene activities, to ensure adequate control of evidence, including for nuclear forensics purposes, a coordinated research project on the application of nuclear forensics in illicit trafficking, and a proposal for international cooperation with nuclear forensics databases and the development of guidelines for establishing databases. Nuclear forensics will continue to be an important ...

106

The Secretion of ?-Ecdysone by the Prothoracic Glands of Manduca sexta In Vitro  

UK PubMed Central (United Kingdom)

Prothoracic glands of tobacco hornworm larvae cultured in vitro secrete into the culture medium a substance which was active in ecdysone bioassays and determined to be ecdysone-like...Full Text Available

1974-03-01

107

Sugarcane Culture and Syrup Production.  

Science.gov (United States)

The publication gives the basic information needed by growers of syrup sugarcane. It includes descriptions of the sugarcane plant characteristics needed in syrup varieties, the best varieties, cultural requirements and practices, and the diseases and inse...

1988-01-01

108

Culture of cells from beagles with bronchioloalveolar carcinoma  

International Nuclear Information System (INIS)

Cell cultures were prepared from lung tumors occurring in beagles following exposure to inhaled plutonium. Morphologic and growth characteristics of two of these cell lines are described.

1977-05-01

109

Culture and cooperation  

UK PubMed Central (United Kingdom)

Does the cultural background influence the success with which genetically unrelated individuals cooperate in social dilemma situations? In this paper, we provide an answer by analysing the data of Full Text Available

2010-09-12

110

CONSTRAINTS TO CRASSOSTREA ARIAKENSIS AQUACULTURE: SEASON AND METHOD OF CULTURE STRONGLY INFLUENCE SUCCESS OF GROW-OUT  

Science.gov (United States)

... of culture season and method on benefits of oyster aquaculture may be obtained without appreciable risk of unplanned ... ...

111

Reconsidering the site requirements for NPP on Olt River  

International Nuclear Information System (INIS)

Site studies for CANDU type NPP began in a careful manner since 1982 as a first part of the Nuclear Power Plant Romanian Program adopted by political and governmental authorities at the time. A team was charged to develop all packages of the necessary main studies. The first Romanian NPP CANDU 6 type reactor gone to erection on Cernavoda site, planned to have 5 units and, like Wolsong NPP, applied the same design for the nuclear island. For the BOP parts the ANSALDO-GE project was applied with a thorough concern about requirements raised by connection to NSP. The first mission of design and research multi-branch team was to adapt the NPP Cernavoda project having an open water cooling circuit 'once-through' to the new parameters of a close recirculation water cooling circuit. Also, the structural design was re-evaluated for the case of soft foundation strata instead of hard rock ones. The close recirculation water cooling circuit system was applied for PWR NPP type like in French or ...

2009-10-12

112

Proposal of procedures to prevent errors in radiotherapy based in learned lessons of accidental expositions; Proposta de procedimentos para evitar erros em radioterapia baseados em licoes aprendidas de exposicoes acidentais  

Energy Technology Data Exchange (ETDEWEB)

In order to consider some procedures to prevent errors in radiotherapy based in learned lessons of accidental expositions and in accordance with information contained in international reports elaborated by International Atomic Energy Agency (IAEA) and of the data base availability by the European group Radiation Oncology Safety Information System (ROSIS) on the events, a research of the occurred errors was performed. For the evaluation of the incidents a data base based in the ROSIS and added plus a parameter was created 'type of error'. All the stored data make possible the evaluation of the 839 incidents in terms of frequency of the type of error, the process of detention, the number of reached patients and the degree of severity. Of the 50 types of found errors, the type of error more frequently was 'incorrect treatment coordinate', confirmed with the data of literature and representing 28,96 por cent of ...

2007-07-01

113

Nuclear raw materials: Developing resources through technical co-operation  

International Nuclear Information System (INIS)

This article presents an overview of the IAEA's technical co-operation activities in the field of nuclear raw materials, particularly looking at recent developments and trends influencing future directions

1993-09-01

114

IAEA RESEARCH CONTRACTS. THIRD ANNUAL REPORT. Technical Reports Series No. 16  

Science.gov (United States)

Brief summaries of all final reports relating to contracts that were completed during 1962 are presented. 20 summaries are included. (P.C.H.)

1963-01-01

115

End user needs for enhanced IAEA Safeguards Information Management Capabilities  

International Nuclear Information System (INIS)

The International Atomic Energy Agency is undertaking a program for strengthening its safeguards on the recognition that safeguards must give assurance not only of the non-diversion of declared material or that declared facilities are not being misused, but also of the absence of any undeclared nuclear activities in States which have signed comprehensive safeguards agreements with the Agency. The IAEA has determined that the detection of undeclared nuclear activities and the creation of confidence in the continuing peaceful use of declared material and facilities is largely dependent on more information being made available to the Agency and on the capability of the Agency to make more effective use of this additional information, as well as existing information.

116

Development of radioimmunometric assays and kits for non-clinical applications. Proceedings of a final research coordination meeting  

International Nuclear Information System (INIS)

Immunoassays are versatile analytical techniques that had a leading role in various clinical applications, during the last four decades. The studies carried out by Rosalyn Yalow, Solomon Berson and Roger Ekins in the 1960s gave a breakthrough in the development of this novel analytical method. Sensitivity up to femtomolar concentrations, high specificity and universal application to different classes of molecular species made immunoassay a very useful tool in analytical investigation. The expertise acquired by immunochemists in producing antibodies against any antigen and the ability of radiochemists in labeling the antigens with "1"2"5I without affecting the active site are the two main factors responsible for the above development. There are concerns about the safety and health of humans due to the high-level contamination of environment by pesticides, industrial compounds and metals, anabolic steroids in milk and meat products, and presence of mycotoxins in food ...

2004-12-06

117

Radiation effects on the shoot tip culture of chrysanthemum  

International Nuclear Information System (INIS)

Japanese (Mar 1974). Japan Mabuchi, Toshio Kuwada, Hikaru . Kagawa Univ.,

120

Organizational Culture and Changes of Command  

Science.gov (United States)

... The OER Support Form and NCOER Counselling Worksheet provide a way to match individual and organizational goals. ...

1991-04-26

128

An efficient in vitro plantlet regeneration of Cryptocoryne wendtii and Cryptocoryne becketti through shoot tip culture  

British Library Electronic Table of Contents (United Kingdom)

An efficient micropropagation protocol was established for Cryptocoryne wendtii and Cryptocoryne becketti using shoot tips explants. Multiple shoots were induced from shoot tip explants of both species cultured on agar-gelled as well as liquid MS medium supplemented with 0.5?mg/L BA and 0.2?mg/L IBA (proliferation medium). The multiple shoots of both the species formed on agar-gelled as well as liquid medium were vigorously growing with well-developed roots and leaves after 4?weeks of culture. Highest number of multiple shoots was obtained from shoot tip explants of both the species cultured in liquid proliferation medium after 4?weeks of culture. The shoot tip explants of C. wendtii and C. becketti, that were cultured in liquid proliferation medium (2?weeks) followed by culturing on agar-...

2011-01-01

129

Propagation of jarrah (Eucalyptus marginata) by organ and tissue culture  

Energy Technology Data Exchange (ETDEWEB)

Micropropagation methods are described for the production of clonal lines from Eucalyptus marginata (jarrah) seedlings. Nodal explants from mature trees can also yield shoot cultures, but a high frequency of contamination occurs among such explants. Uncontaminated callus cultures can be produced from mature trees by culturing stamen filaments and shoots can subsequently be regenerated from this callus. The rooting percentage of shoot cultures from either nodes or stamen callus of mature trees is low compared with that from seedling explants. Considerable variation was observed between trees in the ability of stamen callus to regenerate shoots and in the frequency of rooting. (Refs. 27)

1982-01-01

130

From gene manipulation to forest establishment: shoot cultures of woody plants can be a central tool  

Energy Technology Data Exchange (ETDEWEB)

Establishing germplasm of woody plants in microculture as shoot cultures has proved to be an effective method of overcoming many of the obstacles in working with these crops. Shoot cultures eliminate the changes associated with seasonal growth cycles and phase change and put large plants into a more manageable form. Well-established shoot cultures are central to successful clonal propagation systems for forest trees as well as to genetic improvement based on the use of cellular techniques such as protoplast manipulation. The physiological basis as to why tissues from shoot cultures are so readily manipulated is not well understood.

1985-05-01

131

Convoluted cells as a marker for maternal cell contamination in CVS cultures  

DEFF Research Database (Denmark)

In order to identify cells of maternal origin in CVS cultures, tissue from 1st trimester abortions were cultivated and the cultures stained in situ for X-chromatin. Convoluted cells and maternal fibroblasts were found to be positive. By chromosome analysis of cultures from 105 diagnostic placenta biopsies, obtained by the transabdominal route, metaphases of maternal origin were found in nine cases. In eight of these cases colonies of convoluted cells were observed. We conclude that convoluted cells are of maternal origin and are a reliable marker for maternal cell contamination in CVS cultures.

1987-01-01

132

Traces of evidence. Nuclear forensics and illicit trafficking  

International Nuclear Information System (INIS)

An IAEA databank lists a number of reported cases of illicitly trafficked nuclear or other radioactive materials. Apart from the traditional concern with nuclear proliferation, the post September 11th public is now wary of a possible attack by terrorists with a nuclear or radiation dispersion device (RDD). Until now, the seized quantities have not been sufficient to manufacture a nuclear explosive device, but they might be enough to construct an RDD. Recognizing the latent global challenge to public health and safety, the G8 States (Japan, USA, Germany, France, UK, Italy, Canada, and Russia) have called for 'joint international efforts to identify and suppress illicit supply' of, and demand for, nuclear material and to deter potential traffickers. One measure gaining in significance is to identify seized material and trace it back to its origin the objective of an emerging science known as nuclear forensics. Repeatedly nuclear or other ...

2003-06-01

133

Safety in the forefront  

Energy Technology Data Exchange (ETDEWEB)

Safety in general and harmonization of International Maritime Organization rules on mobile offshore drilling rig operation in particular are discussed. The improvement of the industry's safety record is also discussed.

1985-02-01

134

Effectively managing nuclear risk through human performance improvement  

International Nuclear Information System (INIS)

Full text: The US commercial nuclear industry has just completed an outstanding decade of plant performance. Safety levels and electric production are at unprecedented high levels and continue to exceed even high industry goals. Nuclear energy continues to keep the highest priority on performance improvement programs and highly trained/qualified people that maintain its record setting safety and reliability of operations. While the industry has maintained a consistently high level of performance, the advent of deregulation and the consolidation of NPP ownership, as well as the current climate of concern about both rising energy costs and availability of power, has raised the standard for nuclear energy's level of competitiveness in today's market place. The resulting challenge is how to more effectively manage risk and improve performance even further in a generally high performing organization. Newer technology and more training by themselves ...

135

Culture-area relation in Axelrod's model for culture dissemination  

CERN Document Server

A salient facet of Axelrod's model for culture dissemination or social influence is the existence of many multicultural absorbing states. The dependence of the number $C$ of different, coexisting cultures on the size $A$ of the territory or, equivalently, on the number of agents -- the culture-area relation -- is investigated through extensive simulations. This relation exhibits a strong qualitative dependence on the two parameters of the model, namely, the number $F$ of culture features and the number $q$ of values that each feature can take on. We find that a non-monotonous culture-area relation, for which the number of cultures decreases when the area grows beyond a certain size, occurs for $q$ smaller than a threshold value $q_c = q_c (F)$ provided that $F \\geq 3$. In the limit of infinite area, this threshold value signals the onset of a discontinuous ...

2009-01-01

136

A cultural research approach to instrument development: the case of breast and cervical cancer screening among Latino and Anglo women.  

Science.gov (United States)

To illustrate the implementation of a bottom-up approach to the study of culture in health disparities, this article describes the development of a cultural cancer screening scale (CCSS) using mixed methodologies. The aim was to identify cultural factors relevant to breast and cervical cancer screening, develop an instrument to assess them and examine its preliminary psychometric properties among Latin American (Latino) and non-Latino White (Anglo) women in Southern California. Seventy-eight Latino and Anglo women participated in semi-structured interviews, which were content coded based on Triandis' methods for the analysis of subjective culture. Based on the emerging cultural elements, items relevant to cancer screening were developed and pilot tested with 161 participants. After the instrument was refined, 314 Latino and Anglo women from various socioeconomic backgrounds ...

2010-09-23

137

Implementation of integrated safeguards in Nuclear Fuel Plant at Pitesti, Romania  

International Nuclear Information System (INIS)

The nuclear activity was conducted for many years in Romania under Traditional Safeguards (TS) and has developed in good conditions the specific nuclear safeguards. Now there is a good opportunity to improve the performance and quality of the safeguards activity and at the same time to increase the accountancy and control of nuclear materials by passing to Integrated Safeguards (IS) implementation. The legal framework is the Law 100/2000 for ratification of the Protocol between Romania and International Atomic Energy Agency (IAEA), additional completion to the Agreement between the Socialist Republic of Romania Government and IAEA relating to safeguards. It is part of the Treaty on the non-proliferation of nuclear weapons published in the Official Gazette no. 3/31 January 1970, and the Additional Protocol published in the Official Gazette no. 295/ 29.06.2000. The first discussion about Integrated Safeguards (IS) between the Nuclear Fuel Plant ...

2009-10-12

142

NHTSA Contact Information | National Highway Traffic Safety Administra...  

Science.gov (United States)

Skip to Main Content Skip to Main Navigation National Highway Traffic Safety Administration Accessible menu--Sitemap Driving Safety Aggressive Driving Bicycles Child Safety...

2011-09-24

144

Is culture a determinant of financial development?  

British Library Electronic Table of Contents (United Kingdom)

This article investigates the missing link in the literature - whether informal institutions, or what is known as culture, can affect the level of financial development for a country? Our hypothesis stresses that the cultural dimensions of a country can have an impact on its financial set-up. We consider multiple dimensions of culture, identified in the literature by Tabellini (2008), to test our hypothesis. As culture evolves in the form of greater trust, control and other traits, individuals' attitudes towards financial market change, and they engage in greater financial transactions. This, in turn, leads to better financial development. Using quantile estimation technique for a cross section of 90 countries, we find that culture significantly influences the level of financial developmen...

2012-01-01

145

Cultural inheritance and diversification of diet in variable environments  

British Library Electronic Table of Contents (United Kingdom)

Both cultural inheritance and cultural diversification of diets may play an important role in animal evolution. Here we studied how diet innovation and cultural change relate to cultural inheritance in a changing environment. We did this by studying diet cultures in group foragers adapting to environmental change through learning, and the consequences this has for diet differentiation between groups. We used an individual-based model of `monkeys' that learn what to eat in a rich environment, and we changed resource species that are available in the environment. Relative to social influences on learning that arise spontaneously in groups, we found that more direct social learning, in the sense of observing another individual and copying what it eats, helps groups deal with high levels of en...

2009-01-01

146

Achievements and Perspectives of the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management  

International Nuclear Information System (INIS)

The Joint Convention on the Safety of Spent Fuel management and on the Safety of Radioactive Waste Management is the first legal instrument to directly address the safety of spent fuel and radioactive waste management on a global scale. The Joint Convention entered into force in 2001. This paper describes its process and its main achievements to date. The perspectives to establish of a Global Waste Safety Regime based on the Joint Convention are also discussed. (authors)

147

Non-standard natural circulation in primary circuit of VVR-440, behavior of horizontal steam generator in this regime  

Energy Technology Data Exchange (ETDEWEB)

Analyzing various SBLOCA with high pressure safety injection (HPSI) at VVER-440/213, we met a surprising phenomenon - a 'natural' circulation post SG heat transfer reversal. This is not usual, because normal natural circulation (NC) in primary circuit is connected with positive heat transfer at SG. If there is reverse heat transfer at SG (as soon as the break enthalpy outflow is sufficient for removal of reactor decay heat), it should obstruct any natural circulation. The question was, what is the driving force of this 'non-standard natural circulation'. After all we revealed that force - it is the density difference between the colder water in reactor downcomer (cold water from HPSI) and warmer water in inner reactor (lower plenum, core, upper plenum). This phenomenon could be confusing for operating personal, because there would be an opposite temperature difference at the loop than by normal natural circulation (under ...

2001-07-01

148

Non-standard natural circulation in primary circuit of VVR-440, behavior of horizontal steam generator in this regime  

International Nuclear Information System (INIS)

Analyzing various SBLOCA with high pressure safety injection (HPSI) at VVER-440/213, we met a surprising phenomenon - a 'natural' circulation post SG heat transfer reversal. This is not usual, because normal natural circulation (NC) in primary circuit is connected with positive heat transfer at SG. If there is reverse heat transfer at SG (as soon as the break enthalpy outflow is sufficient for removal of reactor decay heat), it should obstruct any natural circulation. The question was, what is the driving force of this 'non-standard natural circulation'. After all we revealed that force - it is the density difference between the colder water in reactor downcomer (cold water from HPSI) and warmer water in inner reactor (lower plenum, core, upper plenum). This phenomenon could be confusing for operating personal, because there would be an opposite temperature difference at the loop than by normal natural circulation (under non-standard NC conditions water is heated ...

2001-03-20

149

Training guidelines in non-destructive testing techniques. 2002 edition  

International Nuclear Information System (INIS)

Non-destructive testing (NDT) is a dynamic technology and progresses with time. Since the issuance of IAEA-TECDOC-628 in 1991, the technology has experienced numerous changes. Advancements in knowledge about the behaviour of materials have led to changes in the applicable NDT codes, standards and specifications. In addition, over the last ten years, as a result of extensive research and development activities worldwide, new NDT techniques and equipment have been developed which are accepted by engineering community. To accommodate the latest developments, modifications are required to training materials. The present publication is an updated version of IAEA-TECDOC-628. The modifications were made during an Advisory Group Meeting, held in Vienna from 25-29 June 2001. The content of the first edition of IAEA-TECDOC-628 has been revised based on the experience of the experts, as well as comments of the end-user industries. The ...

1986-09-21

150

The upgrade of nuclear material accounting system at KAERI  

International Nuclear Information System (INIS)

The agreement between the government of Republic Of Korea (ROK) and the IAEA for the application of safeguards was signed and entered into force in 1975. The Additional Protocol (AP) to the Safeguards Agreement between the ROK and the IAEA was signed in 1999 and entered into force on 19 February 2004. Also, Implementation of Integrated Safeguards (IS) was started on 1 July, 2008 after a draw of the broader conclusion. The IAEA provides 2 hours notification for Random Interim Inspection (RII) under IS. For RII, the facility has to prepare the inspection documents in a short time. Therefore, KAERI (Korea Atomic Energy Research Institute) developed a new computerized nuclear material accounting system named KASIS (KAERI Safeguards Information treatment System) to treat the data by on-line for RII. For the efficient IS implementation, KAERI has a plan to upgrade the system to reflect the accounting approaches or reporting ...

2010-10-01

151

Spent Fuel Transfer to Dry Storage Using Unattended Monitoring System  

Energy Technology Data Exchange (ETDEWEB)

There are 4 CANDU reactors at Wolsung site together with a spent fuel dry storage associated with unit 1. These CANDU reactors, classified as On-Load Reactor (OLR) for Safeguards application, change 16- 24 fuel bundles with fresh fuel in everyday. Especially, the spent fuel bundles are transferred from spent fuel bays to dry storage throughout a year because of the insufficient capacity of spent fuel pond. Safeguards inspectors verify the spent fuel transfer to meet safeguards purposes according to the safeguards criteria by means of inspector's presence during the transfer campaign. For the verification, 60-80 person-days of inspection (PDIs) are needed during approximately 3 months for each unit. In order to reduce the inspection effort and operators' burden, an Unattended Monitoring System (UMS) was designed and developed by the IAEA for the verification of spent fuel bundles transfers from wet storage to dry storage. Based on the enhanced ...

2009-05-15

152

Uptake and Intracellular Activity of Moxifloxacin in Human Neutrophils and Tissue-Cultured Epithelial Cells  

UK PubMed Central (United Kingdom)

The penetration by moxifloxacin of human neutrophils (polymorphonuclear leukocytes [PMN]) and tissue-cultured epithelial cells (McCoy cells) was evaluated by a fluorometric assay. At...Full Text Available

1999-01-01

153

Stimulation of albumin endocytosis by cationized ferritin in cultured aortic smooth muscle cells.  

UK PubMed Central (United Kingdom)

Anionic microdomains within the aortic smooth muscle cell (SMC) surface glycocalyx represent a potential barrier to the endocytosis of anionic plasma proteins. Cultured SMCs exposed briefly to cationized...Full Text Available

1985-12-01

154

Requirements for Extraction of Polyribosomes from Plant Callus Cultures 1  

UK PubMed Central (United Kingdom)

A procedure was developed to isolate polyribosomes from plant cell cultures. Tobacco callus extracted in 10 mm MgCl2, 80 mm KCl, 250 mm sucrose, and 140 mm...Full Text Available

1977-05-01

155

Reduction in the level of intracellular myo-inositol in cultured soybean (Glycine max) cells inhibits cell division.  

UK PubMed Central (United Kingdom)

Although myo-inositol is included in media for the successful growth of plant tissues, the actual requirement of most tissues, including soybean (Glycine max) callus in suspension culture, for myo-inositol...Full Text Available

1990-02-01

156

Propagation of human embryonic and induced pluripotent stem cells in an indirect co-culture system  

UK PubMed Central (United Kingdom)

We have developed and validated a microporous poly(ethylene terephthalate) membrane-based indirect co-culture system for human pluripotent stem cell (hPSC) propagation, which allows real-time...Full Text Available

2010-03-05

157

Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations  

UK PubMed Central (United Kingdom)

With the advent of subgenomic hepatitis C virus (HCV) replicons, studies of the intracellular steps of the viral replication cycle became possible. These RNAs are capable of self-amplification in cultured...Full Text Available

2009-06-01

158

Political Culture and the Nature of Political Participation in Egypt.  

Science.gov (United States)

This thesis analyzes Egyptian political culture and the directive effect which it has upon political development, elite recruitment and the nature of political participation. The pervasive nature of Islam and the centrality of kinship remain the basic fac...

1980-01-01

159

Nitrogen fixation in nitrate reductase-deficient mutants of cultured rhizobia.  

UK PubMed Central (United Kingdom)

Forty-eight mutants unable to reduce nitrate were isolated from "cowpea" Rhizobium sp. strain 32Hl and examined for nitrogenase activity in culture. All but two of the mutants had nitrogenase activity...Full Text Available

1977-02-01

160

Molecular and immunological comparison of human dihydropteridine reductase in liver, cultured fibroblasts and continuous lymphoid cells.  

UK PubMed Central (United Kingdom)

An antiserum was raised in a rabbit against highly purified human liver dihydropteridine reductase (EC 1.6.99.7). Dihydropteridine reductase from human liver, in human cultured fibroblasts and in continuous...Full Text Available

1981-07-01

161

Model for phase III autografts of epidermal cells cultured on a collagen-proteoglycan biomatrix.  

UK PubMed Central (United Kingdom)

The primary aim of this study was to develop a model system that uses epidermal cells (keratinocytes and accessory pigmented cells) cultured on a reconstituted basement membrane biomatrix for use in...Full Text Available

1989-10-01

162

Isolation of a bacterium resembling Pirellula species from primary tissue culture of the giant tiger prawn (Penaeus monodon).  

UK PubMed Central (United Kingdom)

During attempts to establish tissue cultures from hepatopancreas, heart, and hemolymph of the giant tiger prawn (Penaeus monodon), using a medium including penicillin, streptomycin, and amphotericin...Full Text Available

1991-11-01

163

Hanford Cultural Resources Laboratory annual report for fiscal year 1990  

Energy Technology Data Exchange (ETDEWEB)

The Hanford Cultural Resources Laboratory (HCRL) was established by the US Department of Energy Field Office, Richland (RL) in 1987 as part of Pacific Northwest Laboratory. The HCRL provides support for managing the archaeological, historical, and cultural resources of the Hanford Site, Washington, in a manner consistent with federal statutes and regulations. This report summarizes activities of the HCRL during fiscal year (FY) 1990. The HCRL responsibilities have been set forth in the Hanford Cultural Resources Management Plan (HCRMP) as a prioritized list of tasks. The task list guided cultural resources management activities during FY 1990 and is the outline for this report. In order, these tasks were to (1) conduct cultural resource reviews, (2) develop an archaeological resources protection plan, (3) monitor the condition of known archaeological sites, (4) plan a curation ...

1991-11-01

164

Growth temperature reversibly modulates the virulence of Legionella pneumophila.  

UK PubMed Central (United Kingdom)

In chemostat culture, the virulence of two strains of Legionella pneumophila was shown to be significantly (P < 0.05) reduced when the culture temperature was lowered from 37 to 24 degrees C....Full Text Available

1994-07-01

165

Effects of Cycling Temperatures on Fiber Metabolism in Cultured Cotton Ovules 1  

UK PubMed Central (United Kingdom)

The effects of temperature on rates of cellulose synthesis, respiration, and long-term glucose uptake were investigated using cultured cotton ovules (Gossypium hirsutum L. cv Acala...Full Text Available

1992-10-01

166

Discovering Networks of Perturbed Biological Processes in Hepatocyte Cultures  

UK PubMed Central (United Kingdom)

The liver plays a vital role in glucose homeostasis, the synthesis of bile acids and the detoxification of foreign substances. Liver culture systems are widely used to test adverse effects of drugs...Full Text Available

167

Degradation of the Ferric Chelate of EDTA by a Pure Culture of an Agrobacterium sp  

UK PubMed Central (United Kingdom)

A pure culture of an Agrobacterium sp. (deposited as ATCC 55002) that mineralizes the ferric chelate of EDTA (ferric-EDTA) was isolated by selective enrichment from a treatment facility...Full Text Available

1990-11-01

168

Cultural beliefs that may discourage breastfeeding among Lebanese women: a qualitative analysis  

UK PubMed Central (United Kingdom)

BackgroundAlthough the health benefits of breastfeeding are well established, early introduction of formula remains a common practice. Cultural beliefs and practices can have an...Full Text Available

169

Cultural and Contextual Influences on Parenting in Mexican American Families  

UK PubMed Central (United Kingdom)

Family stress theory can explain associations between contextual stressors and parenting. However, the theory has not been tested among Mexican Americans or expanded to include cultural-contextual...Full Text Available

2009-02-01

170

Cell-density-dependent Changes in the Metabolism of Chloronema Cell Cultures  

UK PubMed Central (United Kingdom)

In the growing chloronema cell suspension cultures of the moss Funaria hygrometrica Hedw., activities of several enzymes have been found to be cell-density-dependent. Cyclic nucleotide...Full Text Available

1979-07-01

171

The development of thyroid dose assessment software for nuclear or radiological emergency  

International Nuclear Information System (INIS)

Objective: To develop software for assessment of dose to thyroid gland in emergencies resulting in the release of radioiodine. Methods: Based on procedures for thyroid monitoring and dose assessment introduced in IAEA publications (IAEA-TECDOC-1092 and EPR-MEDICAL-2005), a software was developed with Visual Basic 6.0 program to computerized the methods of thyroid dose estimation. Results: The intake of radioiodine and committed equivalent dose to thyroid could be estimated rapidly and accurately with the present software. Conclusion: The present software provide a practical and rapid tool for estimating thyroid doses received in emergencies resulting in the release of radioiodine by emergency workers and members of public, which is necessary for recommendation of further actions. (authors)

2006-12-01

172

The assessment of soil conservation technologies for sustainable agricultural production. Report of the FAO/IAEA consultants meeting. Working material  

International Nuclear Information System (INIS)

A Consultants' Meeting on 'The assessment of soil conservation technologies for sustainable agricultural production' was held in Vienna at the IAEA Headquarters from May 28-30, 2001. The consultants' presentations reviewed recent advances in the use of fallout radionuclides to measure soil erosion as well as approaches and technologies applied for soil conservation worldwide. Also, activities and experiences of FAO and UNEP in the field of land degradation, soil conservation and related issues were presented. Based on the information provided by the Scientific Secretary, a full project proposal was prepared during the second part of the Consultants' Meeting. The consultants also provided recommendations on the formulation and implementation of a future CRP on the subject.

2001-05-28

173

Packing for food irradiation  

International Nuclear Information System (INIS)

Joint FAO/IAEA/WHO Expert Committee approved the use of radiation treatment of foods. Nowadays food packaging are mostly made of plastics, natural or synthetic, therefore effect of irradiation on these materials is crucial for packing engineering for food irradiation technology. By selecting the right polymer materials for food packaging it can be ensured that the critical elements of material and product performance are not compromised. When packaging materials are in contact with food at the time of irradiation that regulatory approvals sometimes apply. The review of the R-and-D and technical papers regarding material selection, testing and approval is presented in the report. The most information come from the USA where this subject is well elaborated, the International Atomic Energy Agency (IAEA) reports are reviewed as well. The report can be useful for scientists and food irradiation plants operators. (author)

174

Introduction of Member State Support Program (MSSP) of Korea  

International Nuclear Information System (INIS)

The demand of nuclear energy is sharply increasing to solve the energy and environment problems all over the world. The interest and support on the field of nuclear energy in Korea are enlarging as the acceptance of ordering nuclear power plant of UAE. The attention of safeguards is needed to maintain peaceful use of nuclear material and the nuclear nonproliferation as the increasing demand of nuclear energy. The International Atomic Energy Agency (IAEA) invests more in research and development to achieve the effective and efficient implementation of safeguards. Research and development (R and D) in safeguards approaches, procedures and techniques is essential to meeting the safeguards challenges of the future. The IAEA has conducted the R and D program through member state support program (MSSP) since 1977. The objective of this paper is to introduce the MSSP and policy of Korea on MSSP

2010-10-01

175

Energy and nuclear power planning study for Thailand  

International Nuclear Information System (INIS)

The present report describes the study conducted in co-operation with several agencies and organizations from Thailand and covers the energy and electricity requirements and the optimal expansion plans for the power generating system for this country up to year 2011. It is emphasized that the study was carried out by a team of experts from the Electricity Generating Authority of Thailand (EGAT), the National Economic and Social Development Board (NESDB), the National Energy Administration (NEA) and the Office of Atomic Energy for Peace (OAEP), who were fully responsible for all phases of the study, including the production of the present report. The IAEA's responsibility was to provide overall co-ordination and general guidance during the conduct of the study, as well as training and assistance in the implementation and use of the IAEA's computerized planning methodologies on the computer facilities of Thailand. Refs, figs and tabs.

2002-06-16

176

A computer program for rapid calculation of internal committed effective dose through inhalation and ingestion pathways under radiological emergency  

International Nuclear Information System (INIS)

Objective: To establish a computer program for rapid calculation of internal committed effective close through inhalation and ingestion pathways under radiological emergency. Methods: Visual Basic 6.0 is used to compile the generic procedures of internal committed effective dose by inhalation and ingestion in IAEA-TECDOC-1162, Generic Procedures for Assessment and Response during a Radiological Emergency. Results: The assessment methodology of internal committed effective dose by inhalation and ingestion under radiological emergency in the report IAEA-TECDOC-1162 can be coded into a computer program. Conclusions: This research provides a rapid method of assessment for internal committed effective dose by inhalation and ingestion under radiological emergency, and it may provide needed dosimetry data for treatment under emergency response. (authors)

2008-08-01

180

Methods to improve the fertility of poinsettia  

British Library Electronic Table of Contents (United Kingdom)

`Success' or `Red Splendor' plants propagated by shoot tip culture or embryogenesis had higher pollen germination than those propagated by cutting. All clones of `Pepride', `Peter Star' and `Nobel Star' propagated by cutting or by embryogenesis or shoot tip culture did not have viable pollen. `Peter Star' mutants through mutagenesis could recover pollen viability. When both parents were propagated by tissue culture, fruit set increased compared to when one or both parents were propagated by cuttings. Furthermore, the number of the harvested seeds doubled per pollination set, when the tissue culture parents were used instead of cutting-propagation plants.

2008-01-01

181

Educational research in Confucian cultural contexts: reflections on methodology  

British Library Electronic Table of Contents (United Kingdom)

This paper engages in a critical discussion of the key features delineated by the other authors in this Special Issue thus serving as an end-piece for the issue. In particular it touches on three significant concepts. Firstly, it reinforces the importance of context, particularly cultural context in the conduct of research in Confucian cultural settings. Second, as an illustration, it offers a critical perspective on the cultural assumptions that underpin the development of Chinese higher education. Finally, it concludes with some reflections on how other papers in this Special Issue contribute to our understanding of research in CHC contexts.

2011-01-01

182

Factors affecting public and political acceptance for the implementation of geological disposal  

International Nuclear Information System (INIS)

This publication identifies conditions which affect (either increase or decrease) public concern for and political acceptance of the development and implementation of programmes for geological disposal of long lived radioactive waste. It also looks at how interested citizens can be associated in the decision making process in such a way that their input enriches the outcome of a more socially robust and sustainable solution. The publication also considers how to optimize risk management, addressing the needs and expectations of the public and of other relevant stakeholders. Factors of relevance for societal acceptance conditions are identified for the different stages of a repository programme and implementation process, from policy development to the realization of the repository itself. Further, they are described and analysed through case studies from several countries, illustrating the added value of broadening the technical dimension with social dialogue and insight into value ...

2009-09-01

183

Evaluation of fungal bio burden and mycotoxins presence in irradiated samples of medicinal plants purchased from wholesale and retail market  

International Nuclear Information System (INIS)

This present study evaluated the effect of gamma radiation on the fungal survival in packed medicinal plants, purchased from wholesale and retail market, in different period (0 and 30 days) after the treatment. Five kind of medicinal plants (Peumus boldus, Camellia sinensis, Maytenus ilicifolia, Paullinia cupana and Cassia angustifolia), were collected from different cities of Sao Paulo State, and submitted to irradiation treatment using a 60Co source (type Gammacell 220) with doses of 5,0 kGy and 10 kGy and at dose rate of 3.0 kGy/h. Non-irradiated samples (control group) were used for fungal counts and serial dilutions from 10-1 to 10-6 of the samples were seeded in duplicates and plated using the surface culture method in Dichloran 18% Glycerol Agar (DG 18) and were counted after five days at 25 deg C. The control group revealed the presence of genera Aspergillus and Penicillium, which are known as toxigenic fungi and a few samples of control group were within ...

2006-12-20

184

Developing effective professional bus driver health programs: An investigation of self-rated health.  

Science.gov (United States)

The health of professional bus drivers is a critical factor in their driving performance; any impairment may lead to undesired consequences. In an attempt to develop and prioritize health and wellness programs, this study investigates the factors significantly affecting the health conditions of professional bus drivers, as well as the strength of these factors. This study uses self-rated health as the examination measurement. This simple assessment is an inclusive measure of health status for judging health trajectory, and is highly associated with changes in functional ability, including perceived control over driving. This study evaluates driver responses of self-rated health with ordered response models that consider factors such as the driver reported health problems, physical and psychological conditions, demographic factors, driving experience, and working environment. Analysis of a sample of 785 drivers shows that age, body mass index, depression, daily working hours, perceived ...

2011-06-24

185

Beyond the Flatline  

British Library Electronic Table of Contents (United Kingdom)

Abstract High Post-Modernism with its understanding of the significance of the image anticipated the flattening of culture, first in advertising and the printed media, and more recently online. Sam Jacob of FAT speculates on architecture's relationship with the Internet, -a flatland of undifferentiated information-, and how Radical Post-Modernism might be best placed to resist the ubiquity of global culture while reanimating the social and cultural agenda of Modernism and Post-Modernism. Copyright 2011 John Wiley & Sons, Ltd.

2011-01-01

186

Thermokinetic investigation of effects of carbon source on petroleum bacterial growth  

Energy Technology Data Exchange (ETDEWEB)

The growth power-time curves of a strain of petroleum bacteria, B-2, in various kinds of cultures containing different kinds of carbon sources, glucose, n-tetradecane, n-hexadecane and n-octadecane, and different kinds of microemulsions have been determined by using a 2277 Thermal Activity Monitor. The curves showed a single peak for cultures containing a single carbon source, glucose, and two peaks for cultures containing two kinds of carbon sources, glucose and one of the n-alkanes. The first peak indicated that bacteria grew by consuming glucose and the second peak indicated that bacteria grew by consuming n-alkane. The curves were complex when the bacterium grows in a microemulsion culture. According to a kinetic equation of bacterial growth under limited conditions, the rate constants of bacterial growth were obtained. The results showed that the microemulsion culture was more ...

2002-02-07

187

P2Y receptors on astrocytes and microglia mediate opposite effects in astroglial proliferation  

British Library Electronic Table of Contents (United Kingdom)

Nucleotides released upon brain injury signal to astrocytes and microglia playing an important role in astrogliosis, but the participation of microglia in the purinergic modulation of astrogliosis is still unclear. Highly enriched astroglial cultures and co-cultures of astrocytes and microglia were used to investigate the influence of microglia in the modulation of astroglial proliferation mediated by nucleotides. In highly enriched astroglial cultures, adenosine-5?-triphosphate (ATP), adenosine 5?-O-(3-thio)-triphosphate (ATP?S), adenosine 5?-O-(3-thio)-diphosphate (ADP?S; 0.01?1?mM), and adenosine-5?-diphosphate (ADP; 0.1?1?mM) increased proliferation up to 382%, an effect abolished in co-cultures containing 8% of microglia. The loss of ATP proliferative effect in co-cultures is supporte...

2011-01-01

188

Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression  

British Library Electronic Table of Contents (United Kingdom)

Summary Cell senescence is a permanent growth arrest following extended proliferation. Cultured cancer cells including metastatic melanoma cells often appear immortal (proliferate indefinitely), while uncultured benign nevi (moles) show senescence markers. Here, with new explantation methods, we investigated which classes of primary pigmented lesions are typically immortal. Nevi yielded a few proliferating cells, consistent with most nevus cells being senescent. No nevus culture (0/28) appeared immortal. Some thin and thick melanoma cultures proved immortal under these conditions, but surprisingly few (4/37). All arrested cultures displayed three senescence markers in some cells: -galactosidase, nuclear p16, and heterochromatic foci/aggregates. However, melanoma cultures also showed featur...

2011-01-01

189

Importance of serum source for the in vitro replicative senescence of human bone marrow derived mesenchymal stem cells  

British Library Electronic Table of Contents (United Kingdom)

Abstract Human mesenchymal stem cells (hMSCs) may be used for therapeutic applications. Culture conditions such as the serum source may impact on cell quality and the onset of replicative senescence. We have examined the effect of culturing hMSCs in autologous serum (AS) versus fetal bovine serum (FBS) on factors involved in in vitro replicative senescence. hMSCs from four donors were cultured in 10% FBS or 10% AS until they reached senescence. Cells were harvested at early passage and near senescence to study factors known to be involved in cellular senescence. The number of population doublings till senescence was similar for cells cultured in FBS, but varied greatly for hMSCs cultured in AS. FBS cells accumulated in S phase of cell cycle. This could not be explained by increased express...

2011-01-01

190

Heightened awareness of a researcher's own culture through carrying out research on development cooperation  

British Library Electronic Table of Contents (United Kingdom)

In this paper I argue that when a researcher is a research instrument, it is likely that the researcher would develop a heightened awareness of his/her own cultural conditioning, especially in the case of cross-cultural studies. And that such awareness would make him/her realise that one's own cultural background may indeed have an influence on formulating his/her research methodology. The paper is based on my own research project on development cooperation between Japan and Cambodia, whereby I examined the perceptions of Cambodians and Japanese on what an appropriate power relationship between donors and recipients should be. At the outset of my research project, I paid little attention to my own cultural condition and the role it might play in my study, though I was aware that being Japa...

2011-01-01

191

Explant culture of gastrointestinal tissue: a review of methods and applications  

British Library Electronic Table of Contents (United Kingdom)

The gastrointestinal (GI) tract is an important target organ for the toxicity of xenobiotics. The toxic effects of xenobiotics on this complex, heterogeneous structure have been difficult to model in vitro and have traditionally been assessed in vivo. The explant culture of GI tissue offers an alternative approach. Historically, the organotypic culture of the GI tract proved far more challenging than the culture of other tissues, and it was not until the late 1960s that Browning and Trier described the means by which intestinal tissues could be successfully cultured. This breakthrough provided a tool researchers could utilise, and adapt, to investigate topics such as the pathogenesis of inflammatory intestinal diseases, the effect of growth factors and cytokines on intestinal proliferation...

2011-01-01

192

Chondrocytes and bone marrow-derived mesenchymal stem cells undergoing chondrogenesis in agarose hydrogels of solid and channelled architectures respond differentially to dynamic culture conditions  

British Library Electronic Table of Contents (United Kingdom)

Abstract The objective of this study was to investigate how a combination of different scaffold architectures and rotational culture would influence the functional properties of thick cartilaginous tissues engineered using either chondrocytes or bone marrow-derived mesenchymal stem cells (BM-MSCs). Expanded porcine chondrocytes and BM-MSCs were suspended in 2% agarose and cast in custom-designed moulds to produce either regular solid or channelled construct cylinders. The study consisted of three seperate experimental arms. First, chondrocyte and BM-MSC constructs were cultured in free swelling conditions for 9 weeks. Second, constructs were subjected to rotational culture for a period of 3 weeks. Finally, BM-MSC-seeded constructs were subjected to delayed rotational culture, in which cons...

2011-01-01

193

Characteristics of enriched cultures for bio-huff-`n`-puff tests at Jilin oil field  

Energy Technology Data Exchange (ETDEWEB)

Three enriched cultures (48, 15a, and 26a), selected from more than 80 soil and water samples, could grow anaerobically in the presence of crude oil at 30{degrees}C and could ferment molasses to gases and organic acids. Oil recovery by culture 48 in the laboratory model experiment was enhanced by 25.2% over the original reserves and by 53.7% over the residual reserves. Enriched culture 48 was composed of at least 4 species belonging to the genera Eubacterium, Fusobacterium, and Bacteroides. This enriched culture was used as inoculum for MEOR field trials at Jilin oil field with satisfactory results. The importance of the role of these isolates in EOR was confirmed by their presence and behavior in the fluids produced from the microbiologically treated reservoir.

1995-12-31

194

The computerized management for individual monitoring data in Daya Bay Nuclear Power Station  

International Nuclear Information System (INIS)

The authors report the individual monitoring data management system (IDOSE) at Daya Bay Nuclear Power Station. The components of the individual monitoring system, the design requirements of IDOSE, the characteristics and application of this computerized management system are mainly presented. Its application shows that IDOSE meets the requirements of the concerning occupational standards of the state and matches with the requirements of IAEA/ISOE.

195

Status of neutron cross sections for reactor dosimetry  

International Nuclear Information System (INIS)

The status of neutron activation cross sections for some threshold reactions important for reactor materials dosimetry is reviewed. An attempt is made to understand and explain discrepancies between integral and differential data, using recent available experimental results. The importance of standard and benchmark neutron fields for testing differential data for reactor dosimetry is emphasized and the Interlaboratory Reaction Rate (ILRR) program, as well as a similar program pursued by the IAEA, are briefly described.

1976-07-06

196

Quality assurance requirements in various codes and standards  

International Nuclear Information System (INIS)

The quality assurance requirements in various countries and according to various international codes and standards are presented, compared and critically discussed. Cases of developing countries are also discussed, and the use of IAEA code of practice and other codes for quality assurance in these countries is reviewed. Recommendations are made regarding the quality assurance system to be applied for Egypt's nuclear power plants.

197

IAEA advisory group meeting on basic and applied problems of nuclear level densities  

International Nuclear Information System (INIS)

Separate entries were made in the data base for 17 of the 19 papers included. Two papers were previously included in the data base. Workshop reports are included on (1) nuclear level density theories and nuclear model reaction cross-section calculations and (2) extraction of nuclear level density information from experimental data.

1983-04-11

198

IAEA advisory group meeting on basic and applied problems of nuclear level densities  

Energy Technology Data Exchange (ETDEWEB)

Separate entries were made in the data base for 17 of the 19 papers included. Two papers were previously included in the data base. Workshop reports are included on (1) nuclear level density theories and nuclear model reaction cross-section calculations and (2) extraction of nuclear level density information from experimental data. (WHK)

1983-06-01

199

IAEA Co-ordinated Research Program (CRP)  

International Nuclear Information System (INIS)

The Coordinated Research Project is a topical collection of research agreements and contracts. The research contracts are awarded with financial support of about 10-20% of the total contract cost. Among the activities of the project is the organization of consultant group meetings and workshops involving several international experts and representatives of users and developers of border radiation monitoring equipment. The project also supports in coordinating the development of equipment and techniques for up-to-date border monitoring and in establishing of a process for providing nuclear forensics support to member states

2010-05-19

200

Additional protocol between France, EURATOM and IAEA. 2001-2002 ordinary session. Project of law authorizing the ratification of the additional protocol to the agreement between France, the European Atomic Energy Community and the International Atomic Energy Agency relative to the application of warranties in France; Protocole additionnel entre la France, Euratom et l'AIEA. Session ordinaire de 2001-2002. Projet de loi autorisant la ratification du protocole additionnel a l'accord entre la France, la Communaute europeenne de l'energie atomique et l'Agence internationale de l'energie atomique relatif a l'application de garanties en France  

Energy Technology Data Exchange (ETDEWEB)

This additional protocol to the agreement between France, EURATOM and the IAEA aims at reinforcing the nuclear weapons non-proliferation regime. This protocol widens the field of competences of the IAEA with the supply of new information relative to: the civil nuclear cooperation between France and countries having no nuclear weapons in the domain of fuel cycle; the regular inspection of French nuclear facilities; the trade (import and export) of medium- or high-level radioactive wastes containing plutonium, highly enriched uranium or {sup 233}U, and the trade of some non-nuclear equipments or materials with countries having no nuclear weapons. The protocol defines also some practical dispositions relative to the delays and periodicity of controls, to the transmission of data, to the appointment of IAEA inspectors and their access to the facilities and sites considered. The list of the activities and equipments covered by ...

2002-07-01

201

Organ culture of mammalian skin and the effects of ultraviolet light and testosterone on melanocyte morphology and function  

Science.gov (United States)

Scrotal skin of black Long-Evans rats and human thigh skin were maintained in vitro as organ cultures for as long as 14 days, and examined histologically using the combined skin splitting and Dopa techniques. Selected rat skin cultures received testosterone in the culture medium and/or were irradiated with ultraviolet light (290 to 320 nm uvl). With increased time in culture, scrotal melanocytes round up and there is an increase in epidermal pigmentation. Human skin behaves similarly; after eight days in vitro human melanocytes also become rounded, but remain strongly Dopa-positive. Addition of exogenous testosterone to cultured rat skin maintains dendritic morphology of melanocytes, but cell body size is still reduced. uvl irradiation stimulates melanocytes in rat skin cultures, maintaining their dendritic morphology and increasing epidermal and dermal ...

1978-05-01

202

Influence of hormones and medium components on expression of dipyranocoumarins in cell suspension cultures of Calophyllum inophyllum L.  

British Library Electronic Table of Contents (United Kingdom)

Cell suspension cultures were initiated separately from leaf and nodal/internodal calluses for the study of influence of hormones and medium components on biomass growth and expression of dipyranocoumarins. Highest 6.2 times biomass was enhanced in suspension cultures of nodal/internodal callus supplemented with threefold total sulphate. Picloram 8.28mM along with BAP 8.88mM enhanced 295.05 times inophyllum A in suspension cultures of leaf callus whereas IBA 14.70mM along with BAP 4.44mM in suspension cultures of leaf callus enhanced 1065 times inophyllum B. IBA 4.90mM alone in suspension cultures of nodal/internodal callus enhanced maximum 616 times inophyllum C. Only IBA 9.80mM in suspension cultures of leaf callus enhanced 23.22 times inophyllum P. Variation in nitrate and sulphate had ...

2009-01-01

203

Sandia National Laboratories support of the Iraq Nuclear Facility Dismantlement and Disposal Program.  

Energy Technology Data Exchange (ETDEWEB)

Because of past military operations, lack of upkeep and looting there are now enormous radioactive waste problems in Iraq. These waste problems include destroyed nuclear facilities, uncharacterized radioactive wastes, liquid radioactive waste in underground tanks, wastes related to the production of yellow cake, sealed radioactive sources, activated metals and contaminated metals that must be constantly guarded. Iraq currently lacks the trained personnel, regulatory and physical infrastructure to safely and securely manage these facilities and wastes. In 2005 the International Atomic Energy Agency (IAEA) agreed to organize an international cooperative program to assist Iraq with these issues. Soon after, the Iraq Nuclear Facility Dismantlement and Disposal Program (the NDs Program) was initiated by the U.S. Department of State (DOS) to support the IAEA and assist the Government of Iraq (GOI) in eliminating the threats from poorly controlled ...

2009-03-01

204

Computerised, remote monitoring systems for underground coal mines  

Energy Technology Data Exchange (ETDEWEB)

This report presents a study on the use of computerised, continuous remote monitoring systems for fire and explosive atmosphere safety in underground coal mines. The effects of these systems on the safety level in mines are investigated, and the relationship between mine safety regulations and computerised, continuous, remote monitoring is analysed.

1983-03-01

205

Role and responsibilities of Technical Support Division (TSD) of National Nuclear Safety Department (NNSD) in licensing process  

International Nuclear Information System (INIS)

National Nuclear Safety Department is authorized by Infra (Iranian Nuclear Regulatory Authority) for issuing rules and regulation and conducting the licensing and supervisory process for nuclear facilities. The main responsibilities of the NNSD are conducted via five main division are, nuclear codes and standards, Nuclear Safety assessment, Authorization, Inspection and Enforcement and Technical Support. In this paper, the functions and responsibilities of TSD in enhancing nuclear safety are described. Examples of main tasks to support the Nuclear Safety assessment division regarding to technical calculations and research of safety issues in licensing documents are provided. (author)

2007-08-01

206

Survey of systems safety analysis methods and their application to nuclear waste management systems  

Energy Technology Data Exchange (ETDEWEB)

This report reviews system safety analysis methods and examines their application to nuclear waste management systems. The safety analysis methods examined include expert opinion, maximum credible accident approach, design basis accidents approach, hazard indices, preliminary hazards analysis, failure modes and effects analysis, fault trees, event trees, cause-consequence diagrams, G0 methodology, Markov modeling, and a general category of consequence analysis models. Previous and ongoing studies on the safety of waste management systems are discussed along with their limitations and potential improvements. The major safety methods and waste management safety related studies are surveyed. This survey provides information on what safety methods are available, what waste management safety areas have been analyzed, and what are potential areas ...

1981-11-01

208

Fire Safety Concerns in Space Operations - NASA Technical Reports ...  

Science.gov (United States)

familiarity fire triangle (i.e., fuel, oxidant, and ignition source) are excluded. It Is obvious that for the baseline safety goal for spacecraft this ...

209

Explosives - hazard management  

Energy Technology Data Exchange (ETDEWEB)

The management of risks of explosives are described. Administrative and procedural controls are considered. The safety management plan involves hazard identification, risk analysis, assessment and control. The current position of explosives safety is considered. 4 tabs.

1998-12-31

210

Comments on the NRC safety research program budget for fiscal year 1982  

Energy Technology Data Exchange (ETDEWEB)

Recommendations of the Advisory Committee on Reactor Safeguards are presented to the Commissioners for their consideration for FY 82 budget for the NRC safety research program.

1980-07-01

211

Comments on the NRC safety research program budget for Fiscal Year 1983  

Energy Technology Data Exchange (ETDEWEB)

Recommendations of the Advisory Committee on Reactor Safeguards are presented to the Commissioners for their consideration for FY 83 budget for the NRC safety research program.

1981-07-01

212

A bibliography of AECL publications on reactor safety  

International Nuclear Information System (INIS)

AECL Publications on Reactor Safety in CANDU Reactors are listed in this bibliography. The listing is chronological and the accompanying index is by subject. The bibliography will be brought up to date annually. (auth).

1995-05-08

213

Effects of cell concentrations on the survival and repopulation of haemopoietic stem cells in irradiated bone marrow cell culture in vitro  

Energy Technology Data Exchange (ETDEWEB)

Effects of cell concentrations on the survival and repopulation of haemopoietic stem cells after irradiation were studied in the long-term culture of mouse bone marrow cells in vitro. No difference was observed in the survival of the stem cells among cultures in which 0 - 10/sup 7/ cells were re-inoculated on the adherent cell colonies in the culture flask. Stem cells showed a significant proliferation within 1 week and the number of the stem cells exceeded the control in 3 weeks after irradiation in the cultures with less than 10/sup 6/ re-inoculated cells per flask. In contrast, there was a considerable delay in the onset of stem cell proliferation after irradiation in the culture with 10/sup 7/ cells per flask. Based on these results, a possibility that a stimulator of stem cell proliferation, released from irradiated stromal cells, is cancelled by an inhibitory factor produced ...

1981-12-01

214

The safety issues of medical robotics  

International Nuclear Information System (INIS)

In this paper, we put forward a systematic method to analyze, control and evaluate the safety issues of medical robotics. We created a safety model that consists of three axes to analyze safety factors. Software and hardware are the two material axes. The third axis is the policy that controls all phases of design, production, testing and application of the robot system. The policy was defined as hazard identification and safety insurance control (HISIC) that includes seven principles: definitions and requirements, hazard identification, safety insurance control, safety critical limits, monitoring and control, verification and validation, system log and documentation. HISIC was implemented in the development of a robot for urological applications that was known as URObot. The URObot is a universal robot with different modules adaptable for 3D ultrasound ...

2001-08-01

215

Context based inferences in research methodology: the role of culture in justifying knowledge claims  

British Library Electronic Table of Contents (United Kingdom)

Drawing on work in epistemology and the philosophy of science, this paper seeks to provide very general reasons for why a comparative perspective needs to be applied to the inferential procedures of research methodologies where these concern the issue of justifying knowledge claims. In particular, the paper explores the role of culture on a number of important patterns of reasoning that figure in inferential arguments in research methodologies. The patterns examined are induction, both enumerative and analytical, hypothetico-deductive reasoning, and abductive inference. In each case it is argued that substantive theories about the world, including cultures, significantly affect inferential procedures. Examples chosen to illustrate this in more detail mostly reflect the impact of Confucian ...

2011-01-01

216

Cell cultures are more sensitive than Saccharamoyces cervisiae tests for assessing the toxicity of aquatic pollutants  

Energy Technology Data Exchange (ETDEWEB)

Cultured fish and human cells have been used as bioassay systems for the evaluation of the toxicity of aquatic pollutants. Numerous assays using bacteria and yeast have also been used for such purposes. The authors report the toxicity of aquatic pollutants (Cd, Hg, and Ni), using cell culture systems and the yeast Saccharomyces cervisiae test. Cd, Hg, and Ni were chosen as model compounds of pollutants because the related toxicity is now fairly well established.

1988-07-01

217

To talk or not to talk: exploring culturally diverse patients' health information communication choices.  

Science.gov (United States)

As care shifts from institutional to home- and community-based settings, consumer health information technology (IT) must be designed to support patients' new health information management responsibilities. We developed and piloted a new methodology grounded in social network analysis and human factors engineering to explore two often overlooked aspects of this phenomenon: the task of health information communication with members of the social network and the context of culture. Such knowledge is necessary to inform the appropriate design of consumer health IT. We asked a culturally diverse sample of participants to describe what, to whom, why, and how they communicate health information and to provide direct feedback about the methodology. The methodology was acceptable to all participants and able to capture similarities and differences in their health information communication practices. Prior to the main study we will need to refine the ...

2010-11-13

218

The actin content of fibroblasts.  

UK PubMed Central (United Kingdom)

Cultures of chick skin fibroblasts were dissolved in solutions of sodium dodecyl sulphate, and their entire protein content was examined by gel electrophoresis. The most abundant species migrated in...Full Text Available

1975-05-01

219

The Structure of Plant Cell Walls  

UK PubMed Central (United Kingdom)

The molecular structure, chemical properties, and biological function of the xyloglucan polysaccharide isolated from cell walls of suspension-cultured sycamore (Acer pseudoplatanus)...Full Text Available

1973-01-01

220

The I3I Model; Identifying Cultural Determinants of Information ...  

Science.gov (United States)

... Information behavior in dynamic group work contexts: Interwoven situational awareness, dense social networks and contested collaboration in ...

2009-06-01

221

Production of Amylase in Liquid Culture by a Strain of Aspergillus oryzae  

UK PubMed Central (United Kingdom)

The effect of different media and pH on the formation of amylase by Aspergillus oryzae EI 212 is described. Depending upon the composition of the medium and growth...Full Text Available

1970-04-01

222

Novel Cytotoxic Vectors Based on Adeno-Associated Virus  

Wastenet

positive primary PymT breast cancer cells in primary co-cultured tumor tissue, suggesting target specificity of

223

Nineteen Cases of Plague in Arizona  

UK PubMed Central (United Kingdom)

We review the cases of 19 successfully treated plague patients, with emphasis on the clinical and epidemiologic features of the disease. Proper staining and culturing of bubo aspirates; prompt institution...Full Text Available

1985-05-01

224

Metamorphosis of Confucian Heritage Culture and the possibility of an Asian education research methodology  

British Library Electronic Table of Contents (United Kingdom)

This paper opens with a critical analysis of a paradox in contemporary educational research in and about Confucian Heritage Culture (CHC): the assumption that national boundaries coincide with those of a distinct and homogeneous culture, which consistently renders a rather homogenous set of educational phenomena, and collides against a more widely accepted discourse - culture transcends geographical frontiers and is ever evolving in character. It is claimed that this paradox is due to the fact that a thin conception of CHC competes neck-and-neck with a thick conception of it. This paper also addresses the possibility of an ad hoc education research methodology in and about CHC and its compliance issues regarding the mainstream Western research dynamics and philosophy of science. Confucian ...

2011-01-01

225

Invasive Species: State Resources - Colorado  

Science.gov (United States)

of Concern; Parks; Management; Monitoring Exotic and Invasive Species Northern Arizona University. Canyons, Cultures, and Environmental Change. Species of Concern; Contacts;...

2011-10-01

226

Hispanic Cultural Influences on Medical Practice  

UK PubMed Central (United Kingdom)

Because the proportion of Hispanic patients is increasing rapidly, most physicians are now coming into daily contact with Hispanics. In addition to obvious difficulty with oral communication, Hispanics...Full Text Available

1983-10-01

227

Filopodia  

UK PubMed Central (United Kingdom)

The processes of neuronal outgrowth and guidance have typically been studied in classic 2D cell culture systems that do not recapitulate topographical cues present in the in vivo extracellular matrix...Full Text Available

2011-07-01

228

Factors Influencing the Effectiveness of Swimming Pool Bactericides  

UK PubMed Central (United Kingdom)

Techniques for culturing, harvesting, and testing bacteria to evaluate bactericidal chemicals for swimming pools are described. Concentrations of 25, 50, and 100 mg of the chlorine stabilizer cyanuric...Full Text Available

1967-05-01

229

Experience of isolated sleep paralysis in clinical practice in Nigeria.  

UK PubMed Central (United Kingdom)

The supernatural fears associated with the experience of isolated sleep paralysis in the culture of developing countries is sometimes associated with the evolution of somatic symptoms of psychological...Full Text Available

1992-06-01

230

Evaluation of the microbiology of chronic ethmoid sinusitis.  

UK PubMed Central (United Kingdom)

In a prospective study, patients with the diagnosis of chronic ethmoid sinusitis were evaluated microbiologically by using biopsy specimens of the ethmoid sinus mucosa. Microbiology cultures were performed...Full Text Available

1991-11-01

231

Eukaryotic Diversity in an Anaerobic Aquifer Polluted with Landfill Leachate?  

UK PubMed Central (United Kingdom)

Eukaryotes may influence pollutant degradation processes in groundwater ecosystems by activities such as predation on bacteria and recycling of nutrients. Culture-independent community profiling and...Full Text Available

2008-07-01

233

Development and Reproduction of grape phylloxera on irradiated in vitro cultured rootstocks  

International Nuclear Information System (INIS)

The ability of a local strain of grape phylloxera to develop and reproduce on irradiated in vitro cultured rootstocks (Ru140, R99 and 3309C and one local variety 'Helwani' was determined. The results showed that there was great variation in developmental time and reproduction of phylloxera between irradiated and unirradiated in vitro cultured plants. Survival, number of eggs and mean developmental time were greatly reduced when phylloxera was reared on irradiated rootstocks. Based on the examined biological parameters of phylloxera, all tested rootstocks would be more resistant toward such destructive insect when they were irradiated. Thus, phylloxera resistance was enhanced when in vitro cultured plants were treated with low doses of gamma irradiation. (author)

234

Detection and Identification of Bacteria by Gas Chromatography1  

UK PubMed Central (United Kingdom)

Ether extracts of cultures of 29 strains representing 6 species of Bacillus, and of individual strains of Escherichia coli, Aerobacter aerogenes, and Pseudomonas...Full Text Available

1966-07-01

235

Cultures of Death and Politics of Corpse Supply  

UK PubMed Central (United Kingdom)

SummaryNineteenth-century Vienna is well known to medical historians as a leading centre of medical research and education, offering easy access to patients and corpses to students...Full Text Available

2008-01-01

236

Context, Culture, and Connection: Avoiding the Counter ...  

Science.gov (United States)

... Page 25. US Department of Defense, Joint Operation Planning and Execution System, Vol 1, Planning Policies and Procedures (CJCSM 3122.01A). ...

2008-04-23

237

Behavior of osteoblastic cells cultured on titanium and structured zirconia surfaces  

UK PubMed Central (United Kingdom)

BackgroundOsseointegration is crucial for the long-term success of dental implants and depends on the tissue reaction at the tissue-implant interface. Mechanical properties and biocompatibility...Full Text Available

238

Association between the number of blood cultures and appropriateness of care for suspected bacteremic urinary tract infection in the elderly  

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to evaluate the association between the number of blood cultures collected and the appropriateness of care for suspected bacteremic community-acquired urinary tract infection (UTI) in the elderly. We retrospectively evaluated the medical records of 129 patients with UTI >65?years old admitted to a large community-based training hospital in Japan from 1 January 2006 to 31 December 2009. We assessed the association between the number of blood cultures collected and the appropriateness of care received, as well as other factors. Two-thirds of the patients were women, and patients >85?years old accounted for 45.0% of the cases. Most of the organisms isolated from the urine and blood were Escherichia coli (65.4?67.0%). More than two blood cultures were collected ...

2011-01-01

239

Apoptosis at Inflection Point in Liquid Culture of Budding Yeasts  

UK PubMed Central (United Kingdom)

Budding yeasts are highly suitable for aging studies, because the number of bud scars (stage) proportionally correlates with age. Its maximum stages are known ...Full Text Available

240

Accumulation, Activity and Localization of Cell Cycle Regulatory Proteins and the Chloroplast Division Protein FtsZ in the Alga Scenedesmus quadricauda under Inhibition of Nuclear DNA Replication  

British Library Electronic Table of Contents (United Kingdom)

Synchronized cultures of the green alga Scenedesmus quadricauda were grown in the absence (untreated cultures) or in the presence (FdUrd-treated cultures) of 5-fluorodeoxyuridine, the specific inhibitor of nuclear DNA replication. The attainment of commitment points, at which the cells become committed to nuclear DNA replication, mitosis and cellular division, and the course of committed processes themselves were determined for cell cycle characterization. FdUrd-treated cultures showed nearly unaffected growth and attainment of the commitment points, while DNA replication(s), nuclear division(s) and protoplast fission(s) were blocked. Interestingly, the FdUrd-treated cells possessed a very high mitotic histone H1 kinase activity in the absence of any nuclear division(s). Compared with the ...

2008-01-01

241

A Preliminary Study on Dressing Patterns and Incidence of Candidiasis  

UK PubMed Central (United Kingdom)

The incidence of candidiasis in two groups of voluntary participants wearing tight and loose fitted dresses was investigated by both microscopic and cultural techniques for a period of two months....Full Text Available

1982-02-01

242

A Cultural Resources Survey Testing, and Geomorphic ...  

Science.gov (United States)

... Aerial photographs were provided by Mr. Grover P. ... Dr. Beverely J. Watkins conducted the records search and wrote the historic research. x,/ ...

1987-04-01

244

Thermal reactor safety  

International Nuclear Information System (INIS)

Information is presented concerning new trends in licensing; seismic considerations and system structural behavior; TMI-2 risk assessment and thermal hydraulics; statistical assessment of potential accidents and verification of computational methods; issues with respect to improved safety; human factors in nuclear power plant operation; diagnostics and activities in support of recovery; LOCA transient analysis; unresolved safety issues and other safety considerations; and fission product transport.

1990-09-01

245

Thermal reactor safety  

Energy Technology Data Exchange (ETDEWEB)

Information is presented concerning new trends in licensing; seismic considerations and system structural behavior; TMI-2 risk assessment and thermal hydraulics; statistical assessment of potential accidents and verification of computational methods; issues with respect to improved safety; human factors in nuclear power plant operation; diagnostics and activities in support of recovery; LOCA transient analysis; unresolved safety issues and other safety considerations; and fission product transport.

1980-06-01

246

Table of Contents  

British Library Electronic Table of Contents (United Kingdom)

Abstract Overall Numbers Small, But Study Finds SSRI Exposure, Autism Link Additional Drug Safety, Efficacy Data Needed for Pediatric Bipolar Disorder SGA Safety and Efficacy in Children and Adolescents Aripiprazole Safety and Tolerability for Irritability in Autism No Lisdexamfetamine Effect on Sleep Disturbances in Children With ADHD Sickle Cell Disease With Comorbid Depression Homeopathy in Psychiatry Manic Symptoms Induced by Marijuana in a Healthy Adolescent New Warnings Safety Labeling Changes

2011-01-01

248

Optimization of the availability-safety pair for propulsion boilers; Optimisation du couple, disponibilite - surete pour les chaufferies de propulsion  

Energy Technology Data Exchange (ETDEWEB)

The relations between nuclear energy availability and nuclear plant safety are analyzed in the particular cases of naval propulsion nuclear boilers (aircraft carriers, submarines): safety objectives, present and potential risk analysis, optimization of the availability-safety couple, at the design stage and during operation (procedural rules related to the boiler state, real time decisions). 6 fig., 1 tab.

1994-12-31

251

Integrated Safety Management System Phase I Verification for the Plutonium Finishing Plant (PFP) [VOL 1 & 2  

Energy Technology Data Exchange (ETDEWEB)

U.S. Department of Energy (DOE) Policy 450.4, Safety Management System Policy commits to institutionalizing an Integrated Safety Management System (ISMS) throughout the DOE complex as a means of accomplishing its missions safely. DOE Acquisition Regulation 970.5204-2 requires that contractors manage and perform work in accordance with a documented safety management system.

2000-01-10

253

Development of LMFBR safety testing in FFTF  

International Nuclear Information System (INIS)

The Fast Flux Test Facility (FFTF) will provide a prototypic test environment for advanced fuels and materials development within the U. S. LMFBR program. As a fast test reactor, the FFTF also provides a potentially unique capability for conduct of safety experimentation relevant to selected LMFBR safety issues associated with postulated core disruption events. The utility and feasibility of possible extension of FFTF testing into the area of safety research is being investigated. 5 fig.

1976-10-01

254

Design, fabrication, qualification and reliability of the major components of ''MONJU'' from a safety point of view  

International Nuclear Information System (INIS)

This paper will review code and standard and the safety related features of major components of Monju: Components of the Reactor Coolant Boundary; Components of the Reactor Shurdown Systems; Components of the Decay Heat Removal Systems; Components of the Engineered Safety Features; Other Safety Related Components. Their relationship to the system or plant function is emphasized, in reviewing these components.

1982-07-01

255

Cold Vacuum Drying (CVD) Facility Technical Safety Requirements  

Energy Technology Data Exchange (ETDEWEB)

The Technical Safety Requirements (TSRs) for the Cold Vacuum Drying Facility define acceptable conditions, safe boundaries, bases thereof, and management or administrative controls required to ensure safe operation. Controls required for public safety, significant defense-in-depth, significant worker safety, and for maintaining radiological and toxicological consequences below risk evaluation guidelines are included.

1999-12-16

256

The Waste Management Plan integration into Decommissioning Plan of the WWR-S research reactor from Romania  

International Nuclear Information System (INIS)

The paper presents the progress of the Radioactive Waste Management Plan which accompanies the Decommissioning Plan for research reactor WWR-S located in Magurele, Ilfov, near Bucharest, Romania. The new variant of the Decommissioning Plan was elaborated taking into account the IAEA recommendation concerning radioactive waste management. A new feasibility study for WWR-S decommissioning was also developed. The preferred safe management strategy for radioactive wastes produced by reactor decommissioning is outlined. The strategy must account for reactor decommissioning, as well as rehabilitation of the existing Radioactive Waste Treatment Plant and the upgrade of the Radioactive Waste Disposal Facility at Baita-Bihor. Furthermore, the final rehabilitation of the laboratories and reusing of cleaned reactor building is envisaged. An inventory of each type of radioactive waste is presented. The proposed waste management strategy is selected in accordance with the ...

2008-05-28

257

Status of IAEA CRP on Study of Process-Losses in Separation Processes in Partitioning and Transmutation Systems in View of Minimizing Long-Term Environmental Impacts  

Science.gov (United States)

Coordinated Research Project (CRP) was initiated in 2002 by IAEA to enable Member States in developing methodologies for reducing radio-toxic discharge to the environment from nuclear fuel cycle activities and in paving the way for sustainability of nuclear energy. In the past three Research Coordination Meetings (RCM), the following areas of research were examined upon: (1)Basic studies to compare dry partitioning process with aqueous partitioning process; (2)Defining proliferation resistance attributes of partitioning processes; (3) Advanced characterization methods for actinides for measuring the possible material holdup;( 4)Minimization of actinides losses in the waste fraction from the partitioning process;(5)Establishment of separation criteria of partitioning process to minimize environmental impact; and (6)Defining environmental impact associated with partitioning processes. The final TECDOC is currently being prepared to summarize the activities of this ...

2007-07-01

258

Pollution in the Gulf: Monitoring the marine environment  

International Nuclear Information System (INIS)

More than 2 years after the Gulf conflict, scientists are continuing to keep a close watch on marine pollution stemming from the war. Following the conflict in early 1991, major concern was raised worldwide when an estimated four to eight million barrels of crude oil were directly released into the Persian Gulf from the Sea Island terminal in Kuwait. Such amounts clearly made it the largest oil spill in history. The catastrophe was exacerbated when Kuwaiti oil fields were ignited. The magnitude of the pollution, and the types of toxic contaminants involved, led to a worldwide response through the United Nations system. An inter-agency plan of action was developed quickly. As one of its steps, the co-ordinating agency - the United Nations Environment Programme (UNEP) - asked the IAEA's Marine Environment Laboratory (MEL) in Monaco to help make a preliminary assessment of the situation. The Laboratory's main goal in initial surveys was to map the extent and general ...

259

Physical aspects of quality assurance in radiotherapy: A protocol for quality control  

International Nuclear Information System (INIS)

In consistency with the increasing requests from Member States for establishing radiotherapy programmes, an IAEA Technical Co-operation project was initiated in Latin America aimed at improving the physical aspects (as a complement to the clinical issues) of quality assurance in radiotherapy; this ARCAL XXX project (RLA/6/032) was classified as a Model Project of the IAEA. Among the important outcomes of the project were (i) the training of a considerable number of medical physicists in hospitals of the region, (ii) the development of a protocol for quality control procedures, and (iii) the organization of quality audit site visits (to the participant countries) where the implementation in hospitals of the developed quality control procedures is verified. The present publication is the protocol for quality control of the physical aspects of radiotherapy. It contains detailed procedures on what should be measured by a medical physicist in a ...

2009-06-21

260

Elemental investigation of Syrian medicinal plants using PIXE analysis  

Energy Technology Data Exchange (ETDEWEB)

Particle induced X-ray emission (PIXE) technique has been employed to perform elemental analysis of K, Ca, Mn, Fe, Cu, Zn, Br and Sr for Syrian medicinal plants used traditionally to enhance the body immunity. Plant samples were prepared in a simple dried base. The results were verified by comparing with those obtained from both IAEA-359 and IAEA-V10 reference materials. Relative standard deviations are mostly within {+-}5-10% suggest good precision. A correlation between the elemental content in each medicinal plant with its traditional remedial usage has been proposed. Both K and Ca are found to be the major elements in the samples. Fe, Mn and Zn have been detected in good levels in most of these plants clarifying their possible contribution to keep the body immune system in good condition. The contribution of the elements in these plants to the dietary recommended intakes (DRI) has been evaluated. Advantages and limitations of PIXE ...

2010-09-15

261

Challenges in validating the sterilisation dose for processed human amniotic membranes  

Energy Technology Data Exchange (ETDEWEB)

Most of the tissue banks in the Asia Pacific region have been using ionising radiation at 25 kGy to sterilise human tissues for save clinical usage. Under tissue banking quality system, any dose employed for sterilisation has to be validated and the validation exercise has to be a part of quality document. Tissue grafts, unlike medical items, are not produced in large number per each processing batch and tissues relatively have a different microbial population. A Code of Practice established by the International Atomic Energy Agency (IAEA) in 2004 offers several validation methods using smaller number of samples compared to ISO 11137 (1995), which is meant for medical products. The methods emphasise on bioburden determination, followed by sterility test on samples after they were exposed to verification dose for attaining of sterility assurance level (SAL) of 10{sup -1}. This paper describes our experience in using the IAEA Code of Practice in ...

2007-11-15

262

Break Nodalization Influence to IAEA-SPE-4 Test Simulation  

International Nuclear Information System (INIS)

A small break LOCA event simulation with no high pressure injection system available, known as International Atomic Energy Agency Standard Problem Exercise no. 4 (IAEA-SPE-4), was performed on the PMK-2 integral test facility in Budapest in 1993. This paper analyses the response of the PMK-2 facility, a model of VVER-440 nuclear power plant, using the latest released version MOD3.2.1.2 of the RELAP5 thermal-hydraulic code. After several years of the SPE-4 experiment analyses, many problems have emerged and been studied. Main goal of the present analyses was to study the main influencing parameters for adequate modelling of the hexagonal core channel with 19-rod bundle and phenomena during the core uncovery. Some influencing parameters have been identified, mostly on the primary side, but some also on the secondary side. This is exact simulation of main coolant pump coast down, hydro-accumulators water temperature and connections to the primary system. Some concern ...

1998-06-15

263

Role of FFTF in assessing structural feedbacks and inherent safety of LMR's  

International Nuclear Information System (INIS)

The possibility of developing reactor designs with inherent safety characteristics sufficient to provide walk away safety is receiving additional emphasis in the LMR program. A key element in this effort is the recognition that LMR's possess safety characteristics above and beyond those employed in past safety review processes. Some of these additional safety characteristics are due to reactivity feedback effects caused by small structural movements during hypothetical severe design transients. The effects of these characteristics upon the behavior of the FFTF under such transients has been assessed and is discussed in this paper. The paper also presents a preliminary test matrix which might allow experimental verification of the structural reactivity feedback effects. Such experimental verification should be very useful to innovative designers seeking to optimize inherent ...

1985-07-01

264

Role of FFTF in assessing structural feedbacks and inherent safety of LMR's  

International Nuclear Information System (INIS)

The possibility of developing reactor designs with inherent safety characteristics sufficient to provide ''walk away'' safety is receiving additional emphasis in the LMR program. A key element in this effort is the recognition that LMR's possess safety characteristics above and beyond those employed in past safety review processes. Some of these additional safety characteristics are due to reactivity feedback effects caused by small structural movements during hypothetical severe design transients. The effect of these characteristics upon the behavior of the FFTF under such transients has been assessed and is discussed in this paper. The paper also presents a preliminary test matrix which might allow experimental verification of the structural reactivity feedback effects. Such experimental verification should be very useful to innovative designers seeking to optimize inherent ...

1985-04-21

265

Hot Cell Facility (HCF) Safety Analysis Report  

Energy Technology Data Exchange (ETDEWEB)

This Safety Analysis Report (SAR) is prepared in compliance with the requirements of DOE Order 5480.23, Nuclear Safety Analysis Reports, and has been written to the format and content guide of DOE-STD-3009-94 Preparation Guide for U. S. Department of Energy Nonreactor Nuclear Safety Analysis Reports. The Hot Cell Facility is a Hazard Category 2 nonreactor nuclear facility, and is operated by Sandia National Laboratories for the Department of Energy. This SAR provides a description of the HCF and its operations, an assessment of the hazards and potential accidents which may occur in the facility. The potential consequences and likelihood of these accidents are analyzed and described. Using the process and criteria described in DOE-STD-3009-94, safety-related structures, systems and components are identified, and the important safety functions of each SSC are described. Additionally, ...

2000-11-01

266

Development of Reliability Data Management System (RDMS) for safety systems of PHWR type plants  

International Nuclear Information System (INIS)

The Reliability Data Management System (RDMS) for safety systems of PHWR type plants has been developed and utilized in the reliability analysis of the special safety systems of Wolsong Unit 1 with plant overhaul period lengthened. The RDMS is developed for the periodic efficient reliability analysis of the safety systems of Wolsong Unit 1. In addition, this system provides the function of analyzing the effects on safety system unavailability if the test period of a test procedure changes as well as the function of optimizing the test periods of safety-related test procedures. The RDMS can be utilized in handling the requests of the regulatory institute actively with regard to the reliability validation of safety systems.

1999-10-01

267

Development and application of technology-neutral safety requirements for the regulation of new nuclear power reactors  

International Nuclear Information System (INIS)

This paper explores the current trends in development of technology-neutral safety requirements to be used in the regulation of future nuclear power reactors and the role of the quantitative safety goals in the design of reactor safety systems. Establishing the requirements concerning the reliability of safety functions rather than on particular systems employed to achieve the functions, as well as the use of the recommendations of the International Commission on Radiological Protection (ICRP) on protection against potential exposure could form the basis of a technology-neutral framework for safety requirements on new reactor designs. Also it could contribute to international harmonisation of nuclear safety assessment practices as part of the licensing processes for future nuclear power plants. (author)

2009-10-12

268

Use of stable isotopes in developing countries: safe markers for nutrition regime study  

International Nuclear Information System (INIS)

Possible use of stable radioisotopes in studies on nutrition and medicine problems that may be used in investigations of babies, children, pregnant women is shown. Attention is paid to behaviour of limited number of elements: hydrogen, carbon, nitrogen, oxygen. The IAEA plans implementation of a new coordinated research program on use of stable isotopes for studying nutrition problems and related diseases. The program emphasis will be placed on protein metabolism measurements and estimation of energy consumption in control population groups in developing countries.

269

Self-consistent electric field effect on electron transport of ECH plasmas  

Energy Technology Data Exchange (ETDEWEB)

An algorithm is proposed which treats the ECH generated potential in a self-consistent way, by extending the Monte-Carlo Fokker-Planck method used by Murakami [S. Murakami et al., Proc. 17th IAEA Fusion Energy Conference, Yokohama, 1998 (International Atomic Energy Agency, Vienna, in press), paper CN-69/TH2/1]. The additional physics is expected to influence the transport of both thermal and suprathermal electrons in a helical toroidal system. (author)

1999-02-01

270

Production of "9"9Tc"m radiopharmaceuticals for brain, heart and kidney imaging. Final report of a co-ordinated research programme 1991-1994  

International Nuclear Information System (INIS)

The report contains highlights of the achievements of the IAEA Co-ordinated Research programme on Evaluation on the Use of Bulk Reagents for the Production of "9"9Tc_m Radiopharmaceutical and Kits, the participants' summary reports (Argentina, Chile, Greece, India, Indonesia, Japan, Malaysia, Portugal, Russian Federation, Thailand, Uruguay, United States of America), recommended product protocols for five compounds and the participants' recommendations regarding continued support and further directions of co-ordinated research work. Refs, 6 figs, 8 tabs, 6 schemes.

1990-06-24

271

Potential vulnerabilities of nuclear fuel cycle facilities to the year 2000 (Y2K) issue and measures to address them  

International Nuclear Information System (INIS)

The exchange of information and experience among Member Sates is an essential component of the IAEA action plan for addressing the Year 2000 problem. The objective is to enable Member States to identify any gaps in their own conversion programmes, benefit form the experience of others in developing remedial actions and establish the basis for future action to solve remaining problems. Experts in Year 2000 issues particularly those related to digital equipment prepared this report dealing with nuclear fuel cycle facilities

1993-04-18

272

IAEA Coordinated Research Project: Updated decay data library for actinides  

Energy Technology Data Exchange (ETDEWEB)

Recommended nuclear decay data for specific actinides are important in fuel-cycle studies for thermal and fast reactors and inventory studies for safeguards. Therefore, a programme of work was initiated in 2005 to improve the actinide decay data library of the International Atomic Energy Agency through the efforts of a Coordinated Research Project (CRP). The proposed contents of the new database are described, including the agreement to include additional actinides and a significant number of natural decay chain radionuclides. This work is on-going, and is estimated for completion in 2009/10.

2008-06-15

273

Human dietary intakes of trace elements: A global literature survey mainly for the period 1970-1991: 1. Data listings and sources of information  

International Nuclear Information System (INIS)

A database has been compiled on human dietary intakes of trace elements by populations groups living in various countries. The main sources of information used were (1) publications in the open scientific literature, and (2) data submitted to the IAEA in response to a questionnaire. The database contains 1,758 intake values covering 35 elements and 47 countries. In this report the data are listed in various ways to facilitate identification of intake values for any specified country, element and population group. 4 refs, 5 tabs.

274

6. Sample preparation for determining pollutants in components of the environment  

International Nuclear Information System (INIS)

Examples are given of reference materials for radionuclide X-ray fluorescence analysis (RXFA) of the environment processed by the National Bureau of Standards and the IAEA. Methods are described used for preparing standard materials for RXFA. For determining air pollutants the sample is prepared by dry or wet mineralization. Water samples have to be preserved prior to analysis. Insoluble components are separated by filtration or centrifugation. Biological materials must be dehydrated and homogenized. Samples of soil, sludges, sediments and solid wastes will sometimes have to be converted into a solution in some cases a leachate will have to be obtained. (ES).

1983-12-01

275

Performance Testing Methodology for Safety-Critical Programmable Logic Controller  

International Nuclear Information System (INIS)

The Programmable Logic Controller (PLC) for use in Nuclear Power Plant safety-related applications is being developed and tested first time in Korea. This safety-related PLC is being developed with requirements of regulatory guideline and industry standards for safety system. To test that the quality of the developed PLC is sufficient to be used in safety critical system, document review and various product testings were performed over the development documents for S/W, H/W, and V/V. This paper provides the performance testing methodology and its effectiveness for PLC platform conducted by KOPEC

2009-05-01

276

NRC safety research in support of regulation--FY 1989  

Energy Technology Data Exchange (ETDEWEB)

This report, the fifth in a series of annual reports, was prepared in response to congressional inquiries concerning how nuclear regulatory research is used. It summarizes the accomplishments of the Office of Nuclear Regulatory Research during FY 1989. The goal of this office is to ensure that safety-related research provides the technical bases for rulemaking and for related decisions in support of NRC licensing and inspection activities. This research is necessary to make certain that the regulations that are imposed on licensees provide an adequate margin of safety so as to protect the health and safety of the public. This report describes both the direct contributions to scientific and technical knowledge with regard to nuclear safety and their regulatory applications.

1990-04-01

277

NRC safety research in support of regulation, FY 1991. Volume 6  

Energy Technology Data Exchange (ETDEWEB)

This report, the seventh in a series of annual reports, was prepared in response to congressional inquiries concerning how nuclear regulatory research is used. It summarizes the accomplishments of the Office of Nuclear Regulatory Research during FY 1991. The goal of this office is to ensure that safety-related research provides the technical bases for rulemaking and for related decisions in support of NRC licensing and inspection activities. This research is necessary to make certain that the regulations that are imposed on licensees provide an adequate margin of safety so as to protect the health and safety of the public. This report describes both the direct contributions to scientific and technical knowledge with regard to nuclear safety and their regulatory applications.

1992-04-01

278

NRC safety research in support of regulation, FY 1991  

Energy Technology Data Exchange (ETDEWEB)

This report, the seventh in a series of annual reports, was prepared in response to congressional inquiries concerning how nuclear regulatory research is used. It summarizes the accomplishments of the Office of Nuclear Regulatory Research during FY 1991. The goal of this office is to ensure that safety-related research provides the technical bases for rulemaking and for related decisions in support of NRC licensing and inspection activities. This research is necessary to make certain that the regulations that are imposed on licensees provide an adequate margin of safety so as to protect the health and safety of the public. This report describes both the direct contributions to scientific and technical knowledge with regard to nuclear safety and their regulatory applications.

1992-04-01

279

NRC safety research in support of regulation, FY 1990  

Energy Technology Data Exchange (ETDEWEB)

This report, the sixth in a series of annual reports, was prepared in response to congressional inquiries concerning how nuclear regulatory research is used. It summarizes the accomplishments of the Office of Nuclear Regulatory Research during FY 1990. The goal of this office is to ensure that safety-related research provides the technical bases for rulemaking and for related decisions in support of NRC licensing and inspection activities. This research is necessary to make certain that the regulations that are imposed on licensees provide an adequate margin of safety so as to protect the health and safety of the public. This report describes both the direct contributions to scientific and technical knowledge with regard to nuclear safety and their regulatory applications.

1991-04-01

280

NRC safety research in support of regulation, 1988  

Energy Technology Data Exchange (ETDEWEB)

This report, the fourth in a series of annual reports, was prepared in response to Congressional inquiries concerning how nuclear regulatory research is used. It summarizes the accomplishments of the Office of Nuclear Regulatory Research during 1988. The goal of this office is to ensure that safety-related research provides the technical bases for rulemaking and for related decisions in support of NRC licensing and inspection activities. This research is necessary to make certain that the regulations that are imposed on licensees provide an adequate margin of safety so as to protect the health and safety of the public. This report describes both the direct contributions to scientific and technical knowledge with regard to nuclear safety and their regulatory applications.

1989-05-01

281

Development of safety function assessment trees for pressurized heavy water reactor LP/SD operations  

Energy Technology Data Exchange (ETDEWEB)

The objective of Configuration Risk Management Program(CRMP) is to maintain the safety level by assuring the defense-in-depth of nuclear power plant while the configurations are changed during plant operations, especially for the LP/SD. Such a safety purpose can be achieved by establishing the risk monitoring programs with both quantitative and qualitative features. Generally, the quantitative risk evaluation models, i.e., PRA models are used for the risk evaluation during full power operation, and the qualitative risk evaluation models such as safety function assessment trees are used. Through this study, safety function assessment trees were developed.

2003-10-01

282

The Waste Isolation Pilot Plant: A Success Story with International Cooperation  

Energy Technology Data Exchange (ETDEWEB)

The U.S. Department of Energy (DOE) Carlsbad Field Office (CBFO) administers and operates the Waste Isolation Pilot Plant (WIPP) site, which hosts a deep geologic repository for safe disposal of U.S. defense-related TRU waste and is located 42 kilometers (km) east of Carlsbad, New Mexico. CBFO also manages the National Transuranic Waste Program (NTP), which oversees TRU waste management from generation to disposal. The WIPP began receiving waste in March 1999. In some areas of broad international interest, the CBFO has developed a leading expertise through its 25-year WIPP repository and TRU waste characterization activities. In addition to participating in relevant and beneficial experiments, the CBFO will provide the international community convenient access to this information by sponsoring and hosting symposia and workshops on relevant topics and by participation in international waste management organizations and topical meetings. In recognition of the successes at WIPP, the Inter ...

2002-02-26

283

Tissue culture process for the clonal production of loblolly pine plantlets  

Energy Technology Data Exchange (ETDEWEB)

A tissue culture process, organogenesis, is described which involves the stepwise production of a shoot apex, which grows to have leaves and stem and finally roots, culminating in the production of a complete plant. The production and subsequent development of numerous adventitious shoots, preferably from adult tree tissues offers the greatest potential for commercial cloned plantlet production. The process describes these steps for Pinus taeda, the loblolly pine. (Refs. 25).

1981-02-01

284

The Isolation and Characterization of d-Glucose 6-Phosphate Cycloaldolase (NAD-Dependent) from Acer pseudoplatanus L. Cell Cultures  

UK PubMed Central (United Kingdom)

A soluble enzyme system from suspension cultures of Acer pseudoplatanus L. converts d-glucose 6-phosphate to myoinositol. A Mg2+-dependent phosphatase, present in...Full Text Available

1971-09-01

285

Regulation of Indole-3-Acetic Acid Biosynthetic Pathways in Carrot Cell Cultures 1  

UK PubMed Central (United Kingdom)

2,4-Dichlorophenoxyacetic acid (2,4-D) promotes the accumulation of tryptophan-derived indole-3-acetic acid (IAA) in carrot cell cultures during callus proliferation by a biosynthetic pathway that is...Full Text Available

1992-11-01

286

Plant cell engineering: current research, application and future prospects  

International Nuclear Information System (INIS)

This paper reviewed the current status of basic research in plant cell engineering, highlighted the application of embryo culture, double haploid (DH) technology, protoplast culture and somatic hybridization, somaclonal variation, rapid propagation, and bio-products production of plant-origin, and t he prospects. (authors)

2008-10-01

287

Inhibitory effect of transforming growth factor-. beta. (TGF-. beta. ) on insulin-like growth factor 1 (IGF-1)-induced proliferation and differentiation in primary cultures of pig preadipocytes  

Energy Technology Data Exchange (ETDEWEB)

The influence of serum, IGF-1 and TGF-{beta} on the differentiation of preadipocytes was examined in primary cultures of porcine adipose tissue cells. In serum-supplemented or serum-free, IGF-1 (1 and 10 nM) had no effect on total cell number. However, IGF-1 (10nM) increased adipocyte number only in serum-supplemented (1% pig serum) cultures, whereas TGF-{beta} (15 pm) reduced the adipocyte number in the presence and absence of IGF-1. Replication of preadipocytes was analyzed with a ({sup 3}H) thymidine assay. Preadipocyte proliferation (cpm in adipocyte fraction) was increased by IGF-1 (10nM) only in cultures containing pig serum. TGF-{beta} had no effect on preadipocyte proliferation specifically, but slightly increased total ({sup 3}H) thymidine incorporation in cultures with serum. Glycerol phosphate dehydrogenase (GPDH) specific activity was decreased by adding TGF-{beta} to serum-free ...

1990-02-26

288

Inhibitory effect of transforming growth factor-#beta# (TGF-#beta#) on insulin-like growth factor 1 (IGF-1)-induced proliferation and differentiation in primary cultures of pig preadipocytes  

International Nuclear Information System (INIS)

The influence of serum, IGF-1 and TGF-#beta# on the differentiation of preadipocytes was examined in primary cultures of porcine adipose tissue cells. In serum-supplemented or serum-free, IGF-1 (1 and 10 nM) had no effect on total cell number. However, IGF-1 (10nM) increased adipocyte number only in serum-supplemented (1% pig serum) cultures, whereas TGF-#beta# (15 pm) reduced the adipocyte number in the presence and absence of IGF-1. Replication of preadipocytes was analyzed with a ["3H] thymidine assay. Preadipocyte proliferation (cpm in adipocyte fraction) was increased by IGF-1 (10nM) only in cultures containing pig serum. TGF-#beta# had no effect on preadipocyte proliferation specifically, but slightly increased total ["3H] thymidine incorporation in cultures with serum. Glycerol phosphate dehydrogenase (GPDH) specific activity was decreased by adding TGF-#beta# to serum-free ...

1991-04-21

289

Evaluation of the Bactec MGIT 960 system in combination with the MGIT TBc identification test for detection of Mycobacterium tuberculosis complex in respiratory specimens.  

Science.gov (United States)

The sensitivity and specificity of the MGIT TBc identification (TBc ID) test for Mycobacterium tuberculosis complex (MTC) detection in positive Bactec MGIT cultures were 95.2% and 99.2%, respectively. When MTC-positive results obtained from two additional molecular methods were included, the sensitivity of the MGIT TBc ID test was 85.4%, while that of culture was 95.7%. PMID:21450949

2011-03-30

290

Effect of Elicitation and Changes in Extracellular pH on the Cytoplasmic and Vacuolar pH of Suspension-Cultured Soybean Cells 1  

UK PubMed Central (United Kingdom)

We have employed both 31P nuclear magnetic resonance spectroscopy and two intracellular fluorescent pH indicator dyes to monitor the pH of the vacuole and cytoplasm of suspension-cultured...Full Text Available

1992-02-01

291

Control mechanisms operating for lipid biosynthesis differ in oil-palm (Elaeis guineensis Jacq.) and olive (Olea europaea L.) callus cultures.  

UK PubMed Central (United Kingdom)

As a prelude to detailed flux control analysis of lipid synthesis in plants, we have examined the latter in tissue cultures from two important oil crops, olive (Olea europaea L.) and oil palm (Elaeis...Full Text Available

2002-06-01

292

Soil less culture; I sistemi di coltivazione senza suolo  

Energy Technology Data Exchange (ETDEWEB)

The paper gives a general view of techniques and systems related to soil less culture developed in the last years (on substrate in beg; NFT; Ebb-Flood, aeroponic,..) taking into account their management and problems (water quality, control of plant nutrition and irrigation; substrates; pathological aspects,..). The evolution, now in progress, of soil less culture from open to closed system as a way to realized an environmental friendly growing system, is considered. When plants are grown with open cycle techniques a large amount of waste solution, with an a high content of nutrients, are discharged in soil and water. Furthermore, they need an extra-utilization of water and fertilizers. Another aspect is the utilization of low cost substrates, which can be reused for more than one cultural cycle without negative effects on yield, and also finally discharged without negative effects on the environment. The development of soil ...

1996-01-01

293

Identification of culturable and originally non-culturable endophytic bacteria isolated from shoot tip cultures of banana cv. Grand Naine  

British Library Electronic Table of Contents (United Kingdom)

In this article we describe the identification of endophytic bacteria belonging to three groups isolated from shoot tip cultures of banana cv. Grand Naine in a recent study (Thomas et?al. 2008) based on partial 16S rRNA gene sequence homology analysis. The first group included banana stocks that displayed obvious colony growth on MS based tissue culture medium during the first in?vitro passage. The second group constituted stocks that were tissue index-negative for cultivable bacteria initially but turned index-positive after a few to several (4?8) in?vitro passages while the third group formed one sub-stock that turned index-positive after about 18 passages. The organisms belonged to about 20 different genera comprising of ?, ?, ?-proteobacteria, Gram-positive firmicutes and actinobacteri...

2008-01-01

294

Atrial natriuretic peptide receptor heterogeneity and effects on cyclic GMP accumulation  

Energy Technology Data Exchange (ETDEWEB)

The effects of atrial natriuretic peptide (ANP), oxytocin (OT) and vasopressin (AVP) on guanylate cyclase activity and cyclic GMP accumulation were examined, since these hormones appear to be intimately associated with blood pressure and intravascular volume homeostasis. ANP was found to increase cyclic GMP accumulation in ten cell culture systems, which were derived from blood vessels, adrenal cortex, kidney, lung, testes and mammary gland. ANP receptors were characterized in intact cultured cells using {sup 125}I-ANP{sub 8-33}. Specific {sup 125}I-ANP binding was saturable and of high affinity. Scratchard analysis of the binding data for all cell types exhibited a straight line, indicating that these cells possessed a single class of binding sites. Despite the presence of linear Scatchard plots, these studies demonstrated that cultured cells possess two functionally and physically distinct ANP-binding sites. Most of the ...

1988-01-01

295

Safety significance of ATR passive safety response attributes  

International Nuclear Information System (INIS)

The Advanced Test Reactor (ATR) at the Idaho National Engineering Laboratory was designed with some passive safety response attributes which contribute to the safety of the facility. The three passive safety attributes being evaluated in the paper are: 1) In-core and in-vessel natural convection cooling, 2) a passive heat sink capability of the ATR primary coolant system (PCS) for the transfer of decay power from the uninsulated piping to the confinement, and 3) gravity feed of emergency coolant makeup. The safety significance of the ATR passive safety response attributes is that the reactor can passively respond to most transients, given a reactor scram, to provide adequate decay power removal and a significant time for operator action should the normal active heat removal systems and their backup systems both fail. The ATR Interim Level 1 Probabilistic Risk Assessment (PRA) models ...

1990-03-01

296

The WHO patient safety curriculum guide for medical schools.  

Science.gov (United States)

BACKGROUND: The urgent need for patient safety education for healthcare students has been recognised by many accreditation bodies, but to date there has been sporadic attention to undergraduate/graduate medical programmes. Medical students themselves have identified quality and safety of care as an important area of instruction; as future doctors and healthcare leaders, they must be prepared to practise safe healthcare. Medical education has yet to fully embrace patient safety concepts and principles into existing medical curricula. Universities are continuing to produce graduate doctors lacking in the patient safety knowledge, skills and behaviours thought necessary to deliver safe care. A significant challenge is that patient safety is still a relatively new concept and area of study; thus, many medical educators are unfamiliar with the literature and unsure how to integrate ...

2010-12-01

297

Republished paper: The WHO patient safety curriculum guide for medical schools.  

Science.gov (United States)

BACKGROUND: The urgent need for patient safety education for healthcare students has been recognised by many accreditation bodies, but to date there has been sporadic attention to undergraduate/graduate medical programmes. Medical students themselves have identified quality and safety of care as an important area of instruction; as future doctors and healthcare leaders, they must be prepared to practise safe healthcare. Medical education has yet to fully embrace patient safety concepts and principles into existing medical curricula. Universities are continuing to produce graduate doctors lacking in the patient safety knowledge, skills and behaviours thought necessary to deliver safe care. A significant challenge is that patient safety is still a relatively new concept and area of study; thus, many medical educators are unfamiliar with the literature and unsure how to integrate ...

2011-04-01

298

Research and development on next generation reactor (phase I)  

Energy Technology Data Exchange (ETDEWEB)

The objective of the study is to improve the volume of nuclear power plant which adopts passive safety system concept. The passive safety system reactor is characterized by excellent safety and reliability. But the volume of NSSS (Nuclear Steam Supply System) of the passive safety system reactor is so small that it should be upgraded for commercial operation. For volume upgrade, detailed analyses are performed as follows; core design, hydraulics, design and mechnical structures, and safety analysis. In addition to above analysis, some investigations must be supplied as follows: power density vs. DNB margin decrease, outlet temperature vs. EPRI-URD, additional tests for upgraded reactor, dynamic analysis of mechanical vibration according to expanded reactor vessel and expanded in-core structures, and Merit loss of passive safety system reactor according to design ...

1994-10-01

299

Health, Safety, and Environment Division: Annual progress report 1987  

Energy Technology Data Exchange (ETDEWEB)

The primary responsibility of the Health, Safety, and Environment (HSE) Division at the Los Alamos National Laboratory is to provide comprehensive occupational health and safety programs, waste processing, and environment protection. These activities are designed to protect the worker, the public, and the environment. Many disciplines are required to meet the responsibilities, including radiation protection, industrial hygiene, safety, occupational medicine, environmental science, epidemiology, and waste management. New and challenging health and safety problems arise occasionally from the diverse research and development work of the Laboratory. Research programs in HSE Division often stem from these applied needs. These programs continue but are also extended, as needed to study specific problems for the Department of Energy and to help develop better occupational health and safety ...

1988-04-01

300

Decree of the Czechoslovak Atomic Energy Commission No. 436/1990 on quality assurance of selected facilities with respect to nuclear safety of nuclear facilities  

International Nuclear Information System (INIS)

The Decree specifies basic quality assurance requirements applicable to machines, their parts and materials, civil engineering structures, means for automated control of technological processes including hardware and software, and electricity supply systems related to nuclear safety of nuclear facilities, and stipulates binding procedures for the implementation of technical and organizational provisions associated with the quality of selected equipment to ensure nuclear safety of nuclear facilities. Safety classes are defined for selected equipment. Requirements laid on safety assurance documentation are specified, and requirements placed on safety assurance programmes, their preparation, finalization and approval are defined. Quality assurance requirements are also specified with respect to the designing, manufacture, construction, operation, repair, modification and ...

1995-02-01

301

DOE explosives safety manual  

Energy Technology Data Exchange (ETDEWEB)

The Department of Energy (DOE) policy requires that all DOE activities be conducted in a manner that protects the safety of the public and provides a safe and healthful workplace for employees. DOE has also prescribed that all personnel be protected in any explosives operation undertaken. The level of safety provided shall be at least equivalent to that of the best industrial practice. The risk of death or serious injury shall be limited to the lowest practicable minimum. DOE and contractors shall continually review their explosives operations with the aim of achieving further refinements and improvements in safety practices and protective features. This manual describes the Department's explosive safety requirements applicable to operations involving the development, testing, handling, and processing of explosives or assemblies containing explosives. It is intended to reflect the ...

1991-10-01

302

The role of acid incubation in rapid immobilization of hydrogen-producing culture in anaerobic upflow column reactors  

Energy Technology Data Exchange (ETDEWEB)

An approach of acidification was examined on formation of hydrogen-producing granules and biofilms in upflow column-shaped reactors. The reactors were fed with synthetic glucose wastewater and operated at 37 C and pH 5.5. The acclimated anaerobic culture was inoculated in four reactors designated R1, R2, R3 and R4, with R3 and R4 filled with granular activated carbon as support medium. To unveil the roles of acidification, microbial culture in R2 and R3 was subject to an acid incubation for 24 h by shifting the culture pH from 5.5 to 2.0. The experimental results suggested that the acidification substantially accelerated microbial granulation, but not biofilm formation. Microbial activities were inhibited by the acid incubation for about 78 h, resulting in the retarded formation of biofilms of the acidified culture. Reducing culture pH resulted in improvement in cell surface ...

2008-10-15

303

Safety of pull-type and introducer percutaneous endoscopic gastrostomy tubes in oncology patients: a retrospective analysis  

UK PubMed Central (United Kingdom)

BackgroundPercutaneous endoscopic gastrostomy (PEG) allows long-term tube feeding. Safety of pull-type and introducer PEG placement in oncology patients with head/neck or oesophageal...Full Text Available

304

Safety during the monitoring of diabetic patients: trial teaching course on health professionals and diabetics - SEGUDIAB study  

UK PubMed Central (United Kingdom)

BackgroundSafety for diabetic patients means providing the most suitable treatment for each type of diabetic in order to improve monitoring and to prevent the adverse effects of...Full Text Available

305

Relationship of pharmacokinetics and drug distribution in tissue to increased safety of amphotericin B colloidal dispersion in dogs.  

UK PubMed Central (United Kingdom)

The safety, pharmacokinetics, and distribution in tissue of an amphotericin B (AmB)-cholesteryl sulfate colloidal dispersion (ABCD) were compared with those of micellar amphotericin B-deoxycholate (m-AmB)....Full Text Available

1992-02-01

306

Plutonium Finishing Plant safety evaluation report  

Energy Technology Data Exchange (ETDEWEB)

The Plutonium Finishing Plant (PFP) previously known as the Plutonium Process and Storage Facility, or Z-Plant, was built and put into operation in 1949. Since 1949 PFP has been used for various processing missions, including plutonium purification, oxide production, metal production, parts fabrication, plutonium recovery, and the recovery of americium (Am-241). The PFP has also been used for receipt and large scale storage of plutonium scrap and product materials. The PFP Final Safety Analysis Report (FSAR) was prepared by WHC to document the hazards associated with the facility, present safety analyses of potential accident scenarios, and demonstrate the adequacy of safety class structures, systems, and components (SSCs) and operational safety requirements (OSRs) necessary to eliminate, control, or mitigate the identified hazards. Documented in this Safety Evaluation Report (SER) ...

1995-01-01

307

Performance Assessment of Wolsung Unit 2 Safety Grade Pumps using In-Service Test  

Energy Technology Data Exchange (ETDEWEB)

Nuclear power plant has several safety features and each safety feature is based on the operation of pumps and valves. Therefore, it is an essential basis for the safety of nuclear power plant to keep operational readiness of pumps and valves by In-Service Test (IST). According to Ministry of Education, Science and Technology (MEST) Bulletin 2008-14, the safety functioned pumps and valves of all nuclear power plants of Korea Hydro and Nuclear Power Co. Ltd.(KHNP) have been tested to verify their performance of safety function. Each safety grade pump has own design requirement and should be tested to identify whether it could meet the requirement. Design requirements and test references of all safety grade pumps of Wolsung Nuclear Power Plant Unit 2 (Wolsung Unit 2) were examined in this study. And the results of the performance test of the ...

2008-10-15

308

Performance Assessment of Wolsung Unit 2 Safety Grade Pumps using In-Service Test  

International Nuclear Information System (INIS)

Nuclear power plant has several safety features and each safety feature is based on the operation of pumps and valves. Therefore, it is an essential basis for the safety of nuclear power plant to keep operational readiness of pumps and valves by In-Service Test (IST). According to Ministry of Education, Science and Technology (MEST) Bulletin 2008-14, the safety functioned pumps and valves of all nuclear power plants of Korea Hydro and Nuclear Power Co. Ltd.(KHNP) have been tested to verify their performance of safety function. Each safety grade pump has own design requirement and should be tested to identify whether it could meet the requirement. Design requirements and test references of all safety grade pumps of Wolsung Nuclear Power Plant Unit 2 (Wolsung Unit 2) were examined in this study. And the results of the performance test of the ...

2008-10-01

309

OPERATION CASTLE. Radiological Safety. Volume 2.  

Science.gov (United States)

This report is designed to cover the overall Operation Castle radiological safety matters from the viewpoint of those issues of direct concern to Headquarters, Joint Task Force Seven. It was written for the express purpose of assisting in the development ...

1985-01-01

310

OPERATION CASTLE. Radiological Safety. Volume 1.  

Science.gov (United States)

This report is designed to cover the overall Operation Castle radiological safety matters from the viewpoint of those issues of direct concern to Headquarters, Joint Task Force Seven. It was written for the express purpose of assisting in the development ...

1985-01-01

311

Nuclear Regulatory Commission issuances, June 1984. Volume 19, No. 6  

Energy Technology Data Exchange (ETDEWEB)

This report includes the issuances received during the specified period from the Commission, the Atomic Safety and Licensing Appeal Boards, the Atomic Safety and Licensing Boards, the Administrative Law Judge, the Directors' Decisions, and the Denials of Petitions for Rulemaking.

1984-06-01

312

Nuclear Regulatory Commission issuances  

Energy Technology Data Exchange (ETDEWEB)

This report includes the issuances received during the specified period from the Commission (CLI), the Atomic Safety and Licensing Appeal Boards (ALAB), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM).

1982-02-01

313

Nuclear Regulatory Commission Issuances  

Energy Technology Data Exchange (ETDEWEB)

This report includes the issuances received during the specified period from the Commission (CLl), the Atomic Safety and Licensing Appeal Boards (ALAB), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judge (ALJ), The Directors' Decisions (DD), and the Denials of Petitions For Rulemaking (DPRM).

1982-06-01

314

Nonclinical Safety Profile of Telbivudine, a Novel Potent Antiviral Agent for Treatment of Hepatitis B?  

UK PubMed Central (United Kingdom)

Telbivudine is a novel nucleoside drug recently approved for the treatment of patients with chronic hepatitis B. Its nonclinical safety was evaluated in a comprehensive program of studies, including...Full Text Available

2008-07-01

315

Investigation of the radiological safety concerns and medical history of the late Joseph T. Harding, former employee of the Paducah Gaseous Diffusion Plant  

Energy Technology Data Exchange (ETDEWEB)

An ex-employee's claims that inadequate enforcement of radiation safety regulations allowed excess radiation exposure thereby causing his deteriorating health was not substantiated by a thorough investigation.

1981-03-01

316

Introduction and summary of the 13th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies.  

UK PubMed Central (United Kingdom)

A workshop on alternative toxicological testing methodologies was convened by the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC) 26-31 January 1997 in Ispra, Italy,...Full Text Available

1998-04-01

317

FEMA Media Library: Fire Safety  

Science.gov (United States)

Install. Inspect. Protect. Smoke Alarm Campaign Video 10/28/2009 | 04:09 Cooking_4 Cooking Fire Safety: Watch What You Heat 10/26/2007 | 01:40 Cooking_3 Cooking Fire...

2011-08-20

318

Evaluation of the Sida Support to the Global Safety Partnership.  

Science.gov (United States)

The Global Road Safety Partnership (GRSP) is a global partnership of business, civil society and government working for sustained reduction of road accidents in developing and transition countries. GRSP, which started operations in 1999, has a global secr...

2004-01-01

319

Efficacy and safety of vigabatrin in the long-term treatment of refractory epilepsy  

UK PubMed Central (United Kingdom)

1 The long term safety and efficacy of vigabatrin has been studied in 254 patients with refractory epilepsy (82% with partial seizures) in 23 different clinics in eight European countries....Full Text Available

1989-01-01

320

Efficacy and safety of livwin (polyherbal formulation) in patients with acute viral hepatitis: A randomized double-blind placebo-controlled clinical trial  

UK PubMed Central (United Kingdom)

Objectives:The study was planned to evaluate the efficacy and safety of Livwin (polyherbal formulation) in acute viral hepatitis.Materials...Full Text Available

2010-10-01

321

Efficacy and safety of Ayurvedic medicines: Recommending equivalence trial design and proposing safety index  

UK PubMed Central (United Kingdom)

Ayurvedic drugs have begun to be evaluated in controlled clinical trials. The trials, often placebo controlled, are usually designed to demonstrate superiority. Though the results have been usually...Full Text Available

2010-07-01

322

Concomitant use of ibuprofen and paracetamol and the risk of major clinical safety outcomes  

UK PubMed Central (United Kingdom)

AIMSTo evaluate and compare the risk of specific safety outcomes in patients prescribed ibuprofen and paracetamol concomitantly with those in patients prescribed ibuprofen or paracetamol...Full Text Available

2010-09-01

323

Cardiovascular Safety of Degarelix: Results From a 12-Month, Comparative, Randomized, Open Label, Parallel Group Phase III Trial in Patients With Prostate Cancer  

UK PubMed Central (United Kingdom)

PurposeWe assessed the cardiovascular safety profile of degarelix, a new gonadotropin-releasing hormone antagonist.Materials...Full Text Available

2010-12-01

324

Challenges for Lithuania: Ignalina NPP Early Closure  

International Nuclear Information System (INIS)

As a condition of accession into the European Union (EU), Lithuania is committed to the closure and decommissioning of Ignalina NPP comprising two RBMK-1500 reactor units (Fig. 1). It was agreed in a special protocol to the Accession Treaty that, in return for adequate EU financial assistance, Unit 1 would be closed before 2005 and Unit 2 by the end of 2009. The first unit was duly shut down on December 31, 2004. Lithuania, which has borders with Russia (Kaliningrad territory), Poland, Latvia and Belarus, spent fifty years as part of the Soviet Union and was deeply integrated into its economy and electrical infrastructure. At the break-up of the USSR, Lithuania inherited electricity generating capacity designed to supply the north-west region including ownership of Ignalina NPP located in the north-east of the country. Ignalina NPP Unit 1 was commissioned in 1983, Unit 2 in 1987; the planned lifespan of each unit was 30 years. Construction of a third unit was started but never ...

2008-01-01

325

Studies on the appearance of skeletal anomalies in red porgy: effect of culture intensiveness, feeding habits and nutritional quality of live preys  

British Library Electronic Table of Contents (United Kingdom)

Summary Despite the great interest of red porgy as a new species for Mediterranean aquaculture, its commercial production is constrained by the high incidence of skeletal deformities occurring in this species under culture conditions. Several studies have been conducted to better understand the origin of these anomalies in this species, using different system intensiveness, rotifers enrichment products or rotifers docosahexaenoic acid content. The first study showed that culture intensification increased the number of fish with an extra vertebrae, what was probably related to the different nutritional quality of live preys employed in each treatment, since water temperature, salinity and genetic background were identical for the different batches of fish studied. Total incidence of skeleta...

2010-01-01

326

Social involvement and development as a response to the campus student culture  

British Library Electronic Table of Contents (United Kingdom)

Given the widely accepted notion of whole person education in Confucian societies such as Hong Kong, Mainland China and Singapore, it is surprising that research literature originated in these societies pays little attention to how students learn and develop through out-of-class experiences at university. There is little research evidence on how the prevailing culture among student social communities (residential halls and student societies/clubs) influences students? social involvement and development. This paper examines 42 Chinese students? social experiences and development during their freshman year at a Hong Kong university. The majority of them were intensively involved in out-of-class activities. Their active social involvement was both a response to the culture of student communit...

2011-01-01

327

Rapamycin (sirolimus) protects against hypoxic damage in primary heart cultures via Na^+/Ca^2^+ exchanger activation  

British Library Electronic Table of Contents (United Kingdom)

Aims: Rapamycin (sirolimus) is an antibiotic that inhibits protein synthesis through mammalian targeting of rapamycin (mTOR) signaling, and is used as an immunosuppressant in the treatment of organ rejection in transplant recipients. Rapamycin confers preconditioning-like protection against ischemic-reperfusion injury in isolated mouse heart cultures. Our aim was to further define the role of rapamycin in intracellular Ca^2^+ homeostasis and to investigate the mechanism by which rapamycin protects cardiomyocytes from hypoxic damage. Main methods: We demonstrate here that rapamycin protects rat heart cultures from hypoxic-reoxygenation (H/R) damage, as revealed by assays of lactate dehydrogenase (LDH) and creatine kinase (CK) leakage to the medium, by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-d...

2011-01-01

328

Politics, guanxi and the search for objectivity: the intricacies of conducting educational research in Chinese contexts  

British Library Electronic Table of Contents (United Kingdom)

This article discusses how history, the cultural setting, and the political-ideological contexts may influence educational research in China. It seeks to demonstrate a dichotomy between official and popular discourses, and argues that there is a need for the researcher to understand and interpret the language style used in various interview settings and research publications in China. Further, it is contended that ideology and cultural influences push towards a 'virtuous' or socially acceptable understanding of reality. These ideological and cultural norms may also affect official research data and statistics. Further, the article seeks to demonstrate that for a researcher in China (whether Chinese or not) it is important to cultivate and make use of guanxi (connections), at the same time ...

2011-01-01

329

Patterns of proliferation and differentiation of irradiated haemopoietic stem cells cultured on normal 'stromal' cell colonies in vitro  

Energy Technology Data Exchange (ETDEWEB)

Experiments were designed to elucidate whether or not the irradiated bone marrow cells receive any stimulation for the self-replication and differentiation from normal 'stromal' cell colonies in the bone marrow cell culture in vitro. When irradiated or unirradiated bone marrow cells were overlaid on the normal adherent cell colonies, the proliferation of haemopoietic stem cells was supported, the degree of the stimulation depending on the starting cellular concentration. There was, however, no significant changes in the concentration of either CFUs or CFUc regardless of the dose of irradiation on the bone marrow cells overlaid. This was a great contrast to the dose-dependent decrease of CFUs or CFUc within the culture in which both the stem cells and stromal cells were simultaneously irradiated. These results suggest that the balance of self-replication and differentiation of the haemopoietic stem cells is affected only when ...

1981-09-01

330

Lecturas neobarrocas del Espejo de paciencia y reconceptualizaciones de la naci?n: Jos? Lezama Lima, Cintio Vitier y Severo Sarduy  

British Library Electronic Table of Contents (United Kingdom)

This article examines the successive reinterpretations of one of Cuba?s foundational texts, namely the Espejo de paciencia (?Model of Patience??, 1608) by Silvestre de Balboa, as a baroque poem. The revalorization of the baroque by twentieth-century Cuban authors and critics has been explained as a consequence of the erasure of indigenous cultures and the subsequent imposition of a metropolitan culture. In this sense, the baroque is supposed to be paradigmatic for ?roots thinking?? about nation-building and culture. The readings of Balboa?s poem by neo-baroque writers such as Jos? Lezama Lima, Cintio Vitier and Severo Sarduy, however, put forward a transhistorical vision of the baroque and Cubanhood as an eternal and immutable phenomenon or, alternatively, a reading that privileges the tec...

2010-01-01

331

Environmental, scanning electron and optical microscope image analysis software for determining volume and occupied area of solid-state fermentation fungal cultures  

British Library Electronic Table of Contents (United Kingdom)

Abstract Here we propose a software for the estimation of the occupied area and volume of fungal cultures. This software was developed using a Matlab platform and allows analysis of high-definition images from optical, electronic or atomic force microscopes. In a first step, a single hypha grown on potato dextrose agar was monitored using optical microscopy to estimate the change in occupied area and volume. Weight measurements were carried out to compare them with the estimated volume, revealing a slight difference of less than 1.5%. Similarly, samples from two different solid-state fermentation cultures were analyzed using images from a scanning electron microscope (SEM) and an environmental SEM (ESEM). Occupied area and volume were calculated for both samples, and the results obtained w...

2011-01-01

332

Developing defined culture systems for human pluripotent stem cells  

British Library Electronic Table of Contents (United Kingdom)

Human pluripotent stem cells hold promising potential in many therapeutics applications including regenerative medicine and drug discovery. Over the past three decades, embryonic stem cell research has illustrated that embryonic stem cells possess two important and distinct properties: the ability to continuously self-renew and the ability to differentiate into all specialized cell types. In this article, we will discuss the continuing evolution of human pluripotent stem cell culture by examining requirements needed for the maintenance of self-renewal in vitro. We will also elaborate on the future direction of the field toward generating a robust and completely defined culture system, which has brought forth collaborations amongst biologists and engineers. As human pluripotent stem cell re...

2011-01-01

333

Coloring of cultured pearls by gamma-rays irradiation  

International Nuclear Information System (INIS)

Changing cream pearls into bluish-grey by #gamma# ray irradiation is a technique in coloring of pearls. Irradiated pearls are similar in color to cultured blue pearls. The pearl layers hardly change their color but the nuclei change into dark brown by irradiation. Visible light (500 - 700 nm) penetrating the pearl layer is absorbed by dark brown nucleus. The intensity of reflecting light between 400 and 500 nm at pearl surface, therefore, becomes stronger than that between 500 and 700 nm; therefore color of irradiated pearls look bluish-grey. The density of bluish-grey color increases with increasing absorbed doses, but their luster at surface diminishes owing to the deterioration of the pearl layer by prolonged irradiation; high doses irradiation should be avoided. Irradiated pearls show no substantial fading of their color in a year and the rate of the fading is found to be lower than that for cultured blue pearls. (author).

334

Cell culture and gene transcription effects of copper sulfate on Chinese hamster ovary cells  

British Library Electronic Table of Contents (United Kingdom)

Abstract This study reports the effects of varying concentrations of copper sulfate on the metabolic and gene transcriptional profile of a recombinant Chinese hamster ovary (CHO) cell line producing an immunoglobulin G (IgG)-fusion protein (B0). Addition of 50 M copper sulfate significantly decreased lactate accumulation in the cultures while increasing viable cell density and protein titer. These changes could be seen from day 6 and became increasingly evident with culture duration. Reducing the copper sulfate concentration to 5 M retained all the above beneficial effects, but with the added benefit of reduced levels of the aggregated form of the B0 protein. To profile the cellular changes due to copper sulfate addition at the transcriptional level, Affymetrix CHO microarrays were used to...

2011-01-01

335

Biological and morphological characterization of human neonatal fibroblast cell culture B-HNF-1  

British Library Electronic Table of Contents (United Kingdom)

In the present study, human neonatal fibroblasts were isolated from a two-month-old human male. The purpose of the present investigation was the analysis of the morphology (light and transmission electron microscopy), karyotype and growth characteristics of the human neonatal fibroblast cell culture B-HNF-1. Moreover, STR typing and mitochondrial DNA amplification and sequencing was also performed. Analysis of chromosomes count showed that B-HNF-1 cell culture is diploid and has normal male karyotype 46, XY, which was stable during cultivation. The transmission electron microscopy demonstrated the ultra-structure of the B-HNF-1 cells; they have typical morphological features of proteosynthesis-active cells. Large number of fibroblasts bearing different shapes and surface characteristics ad...

2010-01-01

336

A cultural model of household energy consumption  

International Nuclear Information System (INIS)

In this paper, we consider the development of demand-side research, from an early interest in conservation behavior to a later focus on physical, economic, psychological and social models of energy consumption. Unfortunately, none of these models account satisfactorily for measured energy consumption in the residential sector. Growing interest in the end-uses of energy (e.g. in support of load forecasting, demand-side management and least-cost utility planning), increasing international studies of energy use, and continuing work in the energy and lifestyles research tradition now support an emerging cultural perspective on household energy use. The ecological foundations of the cultural model and its applications in energy research are discussed, along with some of the analytic consequences of this approach. (author).

337

Thermodynamic Stable Metal Compositions  

International Science & Technology Center (ISTC)

Thermodynamic Stable Metal Compositions for Improvement of an Operational Safety of Constructional Materials under Conditions of Multifactor Loadings of an Aggressive Environment

338

Thermal-hydraulic testing on a Mitsubishi simplified PWR  

Energy Technology Data Exchange (ETDEWEB)

Mitsubishi is now developing a new Pressurized water reactor (PWR), the Mitsubishi simplified PWR (MS-PWR), which has the innovative features of hybrid safety systems (an optimum combination of passive and active systems) and cooling by horizontal steam generators. In order to confirm the feasibility of the Mitsubishi hybrid safety system, various kinds of safety analyses are performed for loss-of-coolant accident events. In parallel to these safety analysis efforts, the following thermal-hydraulic tests are to be performed: (1) thermal-hydraulic test of a horizontal steam generator; (2) integrated thermal-hydraulic test using a simulation loop for the innovative MS-PWR (SLIM).

1993-01-01

340

Safety analysis and justification for modification of auxiliary feed-water system in Daya Bay Nuclear Power Plant  

International Nuclear Information System (INIS)

The major feed-water line break accident is re-analyzed, which is based on Guangdong Daya Bay nuclear power station final safety analysis report, to justify the impacts of the decreasing of auxiliary feed-water flow rate on the safety margin in Daya Bay. The results showed that the accident analysis can meet the demands of acceptance criteria with the auxiliary feed-water flowrate decreasing from 45 m"3/h to 41.8 m"3/h, and enough safety margin is still retained

2002-06-01

341

Podcast: Viruses and Cooking  

Science.gov (United States)

The Podcast: Viruses and Cooking is a segment of the Web Seminar: Teaching Science with Food Safety , April 27 2010. The podcast is 14 minutes 11

1900-01-01

342

Paul Scherrer Institute Scientific Report 2000. Volume IV: Nuclear Energy and Safety  

Energy Technology Data Exchange (ETDEWEB)

Nuclear energy related research in Switzerland is concentrated at PSI's Nuclear Energy and Safety Research Department (NES). The activities of the department are concentrated on three main domains of: Safety and related problems of operating plants; safety features of future reactor and fuel cycles; waste management. Comprehensive assessments of energy systems are carried out in cooperation with PSI's General Energy Research Department. Many of the programs are part of collaborations with universities, industry, or international organisations. Progress in 2000 in these topical areas is described in this report. A list of scientific publications in 2000 is also provided.

2001-03-01

343

PNNL FY2005 DOE Voluntary Protection Program (VPP) Program Evaluation  

Energy Technology Data Exchange (ETDEWEB)

This document reports the results of the FY 2005 PNNL VPP Program Evaluation, which is a self-assessment of the operational and programmatic performance of the Laboratory related to worker safety and health. The report was compiled by a team of worker representatives and safety professionals who evaluated the Laboratory's worker safety and health programs on the basis of DOE-VPP criteria. The principle elements of DOE's VPP program are: Management Leadership, Employee Involvement, Worksite Analysis, Hazard Prevention and Control, and Safety and Health Training.

2005-01-31

344

Ecologically clean prophylactic food addition from eatable mushroom  

International Nuclear Information System (INIS)

... Safety Institute, GRS, Cologne (Germany) INIS-UA--089 456 p. APPLIED LIFE

2001-04-18

345

Aviation Maintenance Safety Articles, January/February 1990  

Science.gov (United States)

... These are abnormal and an indication of NAVAIRINST 13340.3 identifies these laboratories a possible breakdown in the fuel-handling equip- ...

1990-02-01

346

An overview of FFTF [Fast Flux Test Facility] contributions to Liquid Metal Reactor Safety  

International Nuclear Information System (INIS)

The Fast Flux Test Facility has provided a very useful framework for testing the advances in Liquid Metal Reactor Safety Technology. During the licensing phase, the switch from a nonmechanistic bounding technique to the mechanistic approach was developed and implemented. During the operational phase, the consideration of new tests and core configurations led to use of the anticipated-transients-without-scram approach for beyond design basis events and the move towards passive safety. The future role of the Fast Flux Test Facility may involve additional passive safety and waste transmutation tests. 26 refs.

1990-11-11

347

Safety analysis and license of rod drop time issue at Daya Bay Nuclear Power Plant  

International Nuclear Information System (INIS)

The rod drop time event of the Daya Bay Nuclear Power Plant is caused by the malfunction of the guide tube developed by Framatome. Three temporary solutions were implemented successively and the long term solution was found in the process of searching for the root cause. The different solutions and the root cause are introduced. The safety analysis and license of the solutions are mainly discussed. Experiences and lessons are drawn by summarizing the important items related to nuclear safety.

348

Review and evaluation of the Nuclear Regulatory Commission safety research program for Fiscal Year 1983. Report to the Congress  

Energy Technology Data Exchange (ETDEWEB)

Public Law 95-209 includes a requirement that the Advisory Committee on Reactor Safeguards submit an annual report to Congress on the safety research program of the Nuclear Regulatory Commission. This report presents the results of the ACRS review and evaluation of the NRC safety research program for Fiscal Year 1983. The report contains a number of comments and recommendations.

1982-02-01

349

Review and evaluation of the Nuclear Regulatory Commission safety research program for Fiscal Year 1982. Report to the Congress  

Energy Technology Data Exchange (ETDEWEB)

Public Law 95-209 includes a requirement that the Advisory Committee on Reactor Safeguards submit an annual report to Congress on the safety research program of the Nuclear Regulatory Commission. This report presents the results of the ACRS review and evaluation of the NRC safety research program for Fiscal Year 1982. The report contains a number of comments and recommendations.

1981-02-01

350

Resolution of key safety-related issues in FFTF regulatory review  

International Nuclear Information System (INIS)

The FFTF is an ERDA facility which does not require licensing, but a technical review by NRC is required by ERDA policy. Safety issues which were not fully resolved in the course of the review for construction authorization have been the subject of continuing review since mid-1973. These issues included HCDA energetics, design fallback provisions for additional safety margins, piping integrity, and natural circulation core cooling.

351

Reload safety analysis checklist of Daya Bay Nuclear Power Plant  

International Nuclear Information System (INIS)

The safety analysis checklist scope and the criteria of key parameters needed to be checked for Daya bay reload cycles are introduced. The INCORE code package was used for the safety evaluation of Daya bay unit 2 cycle 2. The method and the contents can not only be applicable for Daya Bay reload cycles but also for Qinshan 600 MW and Qinshan 300 MW reload cycles.

352

Quality assurance requirements for the computer software and safety analyses  

International Nuclear Information System (INIS)

The requirements are given as placed on the development, procurement, maintenance, and application of software for the creation or processing of data during the design, construction, operation, repair, maintenance and safety-related upgrading of nuclear power plants. The verification and validation processes are highlighted, and the requirements put on the software documentation are outlined. The general quality assurance principles applied to safety analyses are characterized. (J.B.). 1 ref.

353

Operation Castle. Radiological Safety. Volume 2. Final report  

Science.gov (United States)

This report is designed to cover the overall Operation Castle radiological safety matters from the viewpoint of those issues of direct concern to Headquarters, Joint Task Force Seven. It was written for the express purpose of assisting in the development of future radiological safety plans by presenting detailed discussion of the problems and solutions arising during Operation Castle.

1985-09-01

354

Operation Castle. Radiological Safety. Volume 1. Final report  

Science.gov (United States)

This report is designed to cover the overall Operation Castle radiological safety matters from the viewpoint of those issues of direct concern to Headquarters, Joint Task Force Seven. It was written for the express purpose of assisting in the development of future radiological safety plans by presenting detailed discussion of the problems and solutions arising during Operation Castle. Included is a discussion of fallout forecasting techniques.

1985-09-01

355

Health physics, safety and medical services report for 1989  

Energy Technology Data Exchange (ETDEWEB)

The Health Physics, Safety and Medical Services Report for Harwell Laboratory for 1989 includes data on the monitoring of the working environment, personnel monitoring, radiological incidents, disposal of radioactive waste and protection of the public. Work on emergency planning, non-radiological health and safety, occupational hygiene, operations support is also discussed. Finally the medical services available and the medical examinations performed are described. (UK).

1990-09-01

356

200 Area Interim Storage Area Technical Safety Requirements  

Energy Technology Data Exchange (ETDEWEB)

The 200 Area Interim Storage Area Technical Safety Requirements define administrative controls and design features required to ensure safe operation during receipt and storage of canisters containing spent nuclear fuel. This document is based on the 200 Area Interim Storage Area, Annex D, Final Safety Analysis Report which contains information specific to the 200 Area Interim Storage Area.

2000-03-15

357

Zinc release from thapsigargin/IP3-sensitive stores in cultured cortical neurons  

UK PubMed Central (United Kingdom)

BackgroundChanges in ionic concentration have a fundamental effect on numerous physiological processes. For example, IP3-gated thapsigargin sensitive intracellular calcium...Full Text Available

358

Why do men marry and why do they stray?  

UK PubMed Central (United Kingdom)

Humans are quite unusual compared to other great apes in that reproduction typically takes place within long-term, iteroparous pairings—social arrangements that have been culturally reified...Full Text Available

2007-07-07

359

Use of microarray technology to assess the time course of liver stress response after confinement exposure in gilthead sea bream (Sparus aurata L.)  

UK PubMed Central (United Kingdom)

BackgroundSelection programs for growth and stress traits in cultured fish are fundamental to the improvement of aquaculture production. The gilthead sea bream (Sparus aurata)...Full Text Available

360

Use of an alkaline phosphatase-labeled synthetic oligonucleotide probe for detection of Campylobacter jejuni and Campylobacter coli.  

UK PubMed Central (United Kingdom)

A commercially available synthetic nucleic acid probe (SNAP) conjugated to alkaline phosphatase was compared with standard culture techniques for detecting Campylobacter species. The SNAP was able to...Full Text Available

1990-07-01

361

Use of Forward Genetics to Discover Novel Regulators of NF-?B  

UK PubMed Central (United Kingdom)

Forward and reverse genetic experiments have both played important roles in revealing critical aspects of mammalian signal transduction pathways in cell culture experiments. Only recently have we begun...Full Text Available

2010-06-01

362

Urinary tract infection in children.  

UK PubMed Central (United Kingdom)

During 1968-77, 572 consecutive children with one or more positive urine cultures who were referred by their family doctors to one paediatric surgical outpatient clinic were investigated and prospectively...Full Text Available

1984-08-04

363

Tissue-engineered product: allogeneic cultured dermal substitute composed of spongy collagen with fibroblasts.  

Science.gov (United States)

Recently, various types of allogeneic skin substitutes including cultured epidermal substitute (CES), cultured dermal substitute (CDS), and cultured skin substitute (CSS), which are composed of keratinocytes and/or fibroblasts as the cellular component(s), have been used as biological wound dressings. In our study, the allogeneic CDS was prepared by plating fibroblasts on a spongy collagen. The clinical evaluation was conducted using fresh or cryopreserved allogeneic CDS. In 145 of our clinical cases, 95% (138/145) of various wounds were evaluated as achieving good or excellent results, including 96% (22/23) of deep dermal burns (DDB) and dermal burns (DB), 100% (53/53) of partial-thickness donor wounds, 91% (21/23) of traumatic skin defects, 100% (5/5) of pressure ulcers, 82% (9/11) of chronic skin ulcers, 100% (6/6) of coverage for debrided DB, and 92% (22/24) of coverage for autologous meshed graft. The results obtained ...

2001-03-01

364

Tick-Borne Relapsing Fever in British Columbia, Canada: First Isolation of Borrelia hermsii  

UK PubMed Central (United Kingdom)

The spirochete that causes tick-borne relapsing fever, Borrelia hermsii, was isolated in pure culture during 1995 and 1996 from three acutely ill human patients infected in southern...Full Text Available

1998-12-01

365

Three-dimensional culture models of mammary gland  

UK PubMed Central (United Kingdom)

The mammary gland is a complex tissue comprised of a branching network of ducts embedded within an adipocyte-rich stroma. The ductal epithelium is a bi-layer of luminal and myoepithelial cells, the...Full Text Available

2009-04-01

366

The protective antigens of equine herpesvirus type 1.  

UK PubMed Central (United Kingdom)

Equine herpesvirus type 1 was cultivated in swine testis cell cultures and partially purified by differential centrifugation and centrifugation in a linear sucrose density gradient. The viral envelope...Full Text Available

1978-04-01

367

The Biosynthesis of ?-Aminolevulinic Acid in Chlorella1  

UK PubMed Central (United Kingdom)

When autotrophically growing cultures of Chlorella are treated with levulinic acid, δ-aminolevulinic acid is excreted into the medium, providing a direct demonstration of α-aminolevulinic...Full Text Available

1970-04-01

368

Sugarcane pests and their management  

Science.gov (United States)

This book chapter discusses sugarcane culture and history, describes arthropod biologies and injury, and identifies sugarcane pest management factors to consider for people interested in commercial sugarcane production. Arthropod groups include 10 orders and 40 families. Sugarcane pest management ...

369

Successful establishment of primary small airway cell cultures in human lung transplantation  

UK PubMed Central (United Kingdom)

BackgroundThe study of small airway diseases such as post-transplant bronchiolitis obliterans syndrome (BOS) is hampered by the difficulty in assessing peripheral airway function...Full Text Available

2009-01-01

370

Stabilization of lignin peroxidases in white rot fungi by tryptophan.  

UK PubMed Central (United Kingdom)

Supplementation of various cultures of white rot fungi with tryptophan was found to have a large stimulatory effect on lignin peroxidase activity levels. This enhancement was greater than that observed...Full Text Available

1997-07-01

371

Stability of Trichomonas vaginalis DNA in Urine Specimens?  

UK PubMed Central (United Kingdom)

Trichomonas vaginalis is an important pathogen in both men and women. Culture is considered the diagnostic gold standard, although studies have shown that PCR is more sensitive than...Full Text Available

2008-05-01

372

Spoligotype Profile of Mycobacterium tuberculosis Complex Strains from HIV-Positive and -Negative Patients in Nigeria: a Comparative Analysis ?  

UK PubMed Central (United Kingdom)

We ran a comparative analysis of all patients for whom a positive culture of Mycobacterium tuberculosis complex was available between April 2004 and October 2005 and whose HIV serology...Full Text Available

2011-01-01

373

Sources of salmonellae in an uninfected commercially-processed broiler flock.  

UK PubMed Central (United Kingdom)

Cultural monitoring was used to study the incidence and sources of salmonellae in a 4160 bird broiler flock during the growing period, transport and processing in a commercial plant. No salmonellae...Full Text Available

1980-07-01

374

Some characteristics of a secreted chlamydial antigen recognized by IgG from C. trachomatis patient sera.  

UK PubMed Central (United Kingdom)

Chlamydia trachomatis serovars release a glycolipid antigen (GLXA) into the culture supernatant during the infective cycle. This antigen is recognized by IgG isolated from humans with a natural chlamydial...Full Text Available

1989-12-01

375

Self-management among Patients Living with Diabetes in the United States Virgin Islands  

UK PubMed Central (United Kingdom)

The United States Virgin Islands (USVI) is facing a diabetes epidemic similar to the one on the U.S. mainland, yet little is known regarding the cultural context relevant to self-management...Full Text Available

2011-01-01

376

Secretion of alpha-hemolysin by bovine mammary isolates of Staphylococcus aureus.  

UK PubMed Central (United Kingdom)

A total of 262 strains of Staphylococcus aureus isolated from the mammary gland of dairy cows were examined for the production of alpha-hemolysin. Strains were cultured in a liquid medium of casein...Full Text Available

1992-07-01

377

Role-Reversal Exercise with Deaf Strong Hospital to Teach Communication Competency and Cultural Awareness  

UK PubMed Central (United Kingdom)

ObjectiveTo implement a role-reversal exercise to increase first-year pharmacy students' awareness of communication barriers in the health care setting, especially for deaf and hard-of-hearing...Full Text Available

2011-04-11

378

Response to a trial of physician-based inpatient order entry.  

UK PubMed Central (United Kingdom)

Our group has developed a physician-operated inpatient order-entry system (BICS-OE). Mindful of the problems inherent in bringing a radical cultural change such as this to the hospital, we conducted...Full Text Available

1993-01-01

379

Real-time monitoring of circadian clock oscillations in primary cultures of mammalian cells using Tol2 transposon-mediated gene transfer strategy  

UK PubMed Central (United Kingdom)

BackgroundThe circadian rhythm in mammals is orchestrated by a central pacemaker in the brain, but most peripheral tissues contain their own intrinsic circadian oscillators. The...Full Text Available

380

Pyogenic Spondylodiscitis after Percutaneous Endoscopic Lumbar Discectomy  

UK PubMed Central (United Kingdom)

We reviewed 9 cases of pyogenic spondylodiscitis following percutaneous endoscopic lumbar discectomy (PELD). Microbiologic cultures revealed 6 causative organisms. Five patients were managed conservatively...Full Text Available

2010-11-01

381

Purification and properties of an endo-1,4-beta-glucanase from Clostridium josui.  

UK PubMed Central (United Kingdom)

An enzyme active against carboxymethyl cellulose (CMC) was purified from the stationary-phase-culture supernatant of Clostridium josui grown in a medium containing ball-milled cellulose. The purification...Full Text Available

1989-07-01

382

Psychometric Properties of the KPAS in Diverse Ethnic Groups of Midlife Women  

UK PubMed Central (United Kingdom)

Although the Kaiser Physical Activity Survey (KPAS) was a potential instrument for cross cultural research of midlife women, little information is available on its reliability and validity among...Full Text Available

2009-12-01

383

Proteome of human colon cancer stem cells: A comparative analysis  

UK PubMed Central (United Kingdom)

AIM: To isolate and identify the biological characteristics of human colon cancer stem cells (SW1116 cells) and further study their proteome.METHODS: SW1116 cells were isolated and cultured with...Full Text Available

2011-03-14

384

Production of placental alkaline phosphatase (PLAP) and PLAP-like material by epithelial germ cell and non-germ cell tumours in vitro.  

UK PubMed Central (United Kingdom)

Placental and placental-like alkaline phosphatase (PLAP) levels in the culture media of 87 cell lines of neoplastic and 'normal' origin were measured by a conventional immunosorbent enzymatic assay...Full Text Available

1994-02-01

385

Production of a cellulolytic enzyme system in mixed-culture solid-state fermentation of soybean hulls supplemented with wheat bran  

British Library Electronic Table of Contents (United Kingdom)

Solid-state fermentation of soybean hulls supplemented with wheat bran using a co-culture of Trichoderma reesei and Aspergillus oryzae was performed. Three parameters - initial moisture content, incubation temperature, and initial pH - were optimized in culture flasks using response surface methodology. Parameter optimization was carried out with respect to filter paper activity and b-glucosidase activity in the culture. Temperature of 30^oC, pH of 5, and moisture content of 70% were found to be optimum. Optimized parameters were used for laboratory scale-up in static tray fermenters. The maximum filter paper activity of 10.7FPU/g-ds and b-glucosidase of 10.7IU/g-ds were obtained after 96-h incubation period in static tray fermenters in agreement with optimized activities at shake flask le...

2010-01-01

386

Product toxicity and cometabolic competitive inhibition modeling of chloroform and trichloroethylene transformation by methanotrophic resting cells.  

UK PubMed Central (United Kingdom)

The rate and capacity for chloroform (CF) and trichloroethylene (TCE) transformation by a mixed methanotrophic culture of resting cells (no exogenous energy source) and formate-fed cells were measured....Full Text Available

1991-04-01

387

Plasmid Transfer between Bacillus thuringiensis subsp. israelensis Strains in Laboratory Culture, River Water, and Dipteran Larvae  

UK PubMed Central (United Kingdom)

Plasmid transfer between strains of Bacillus thuringiensis subsp. israelensis was studied under a range of environmentally relevant laboratory conditions in vitro,...Full Text Available

2001-01-01

388

Phytochelatin Synthesis and Glutathione Levels in Response to Heavy Metals in Tomato Cells 1  

UK PubMed Central (United Kingdom)

Cell suspension cultures of tomato, Lycopersicon esculentum Mill. cv VFNT-Cherry, produce phytochelatins (poly[γ-glutamylcysteinyl]glycines) when exposed to cadmium. The synthesis...Full Text Available

1987-12-01

389

Ordered Assembly of the Adhesive and Electrochemical Connections within Newly Formed Intercalated Disks in Primary Cultures of Adult Rat Cardiomyocytes  

UK PubMed Central (United Kingdom)

The intercalated disk (ID) is a complex structure that electromechanically couples adjoining cardiac myocytes into a functional syncitium. The integrity of the disk is essential for normal cardiac function,...Full Text Available

2010-01-01

390

Oil palm (Elaeis guineensis Jacq.) tissue culture ESTs: Identifying genes associated with callogenesis and embryogenesis  

UK PubMed Central (United Kingdom)

BackgroundOil palm (Elaeis guineensis Jacq.) is one of the most important oil bearing crops in the world. However, genetic improvement of oil palm through conventional...Full Text Available

391

Naturally occurring double-stranded RNA and immune responses. Effects on plaque-forming cells and antibody formation.  

UK PubMed Central (United Kingdom)

A highly purified preparation of double-stranded RNA, obtained from virus-like particles in Penicillium cultures, was found to affert humoral immune responses in mice differentially depending on its...Full Text Available

1975-03-01

392

Mortality, Recruitment and Change of Desert Tree Populations in a Hyper-Arid Environment  

UK PubMed Central (United Kingdom)

BackgroundLong-term vegetation changes in hyper-arid areas have long been neglected. Mortality, recruitment and change in populations of the ecologically and culturally important...Full Text Available

393

Modeling the emergence of universality in color naming patterns  

UK PubMed Central (United Kingdom)

The empirical evidence that human color categorization exhibits some universal patterns beyond superficial discrepancies across different cultures is a major breakthrough in cognitive science. As observed...Full Text Available

2010-02-09

394

Microbial transformation of artificial estrogens of the allenolic group.  

UK PubMed Central (United Kingdom)

When 2,2-dimethyl 3-(2'-naphthyl 6'-hydroxy) pentanoic acid, an artificial estrogen of the allenolic acid group, was added to an exponential-phase growth culture of Neurospora crassa (in Horowitz medium),...Full Text Available

1975-06-01

395

Mesophyll Cell Protoplasts of Potato  

UK PubMed Central (United Kingdom)

Mesophyll cell protoplasts were isolated from potato (Solanum tuberosum L. cv. Russet Burbank) leaves and induced to proliferate in culture. Protoplast division was observed only among...Full Text Available

1977-08-01

396

Medical disclosure and refugees. Telling bad news to Ethiopian patients.  

UK PubMed Central (United Kingdom)

The strong value in American medical practice placed on the disclosure of terminal illness conflicts with the cultural beliefs of many recent refugees and immigrants to the United States, who often...Full Text Available

1992-09-01

397

Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines  

UK PubMed Central (United Kingdom)

IntroductionNormal and neoplastic breast tissues are comprised of heterogeneous populations of epithelial cells exhibiting various degrees of maturation and differentiation. While...Full Text Available

2010-01-01

398

Mapping the Spatiotemporal Dynamics of Calcium Signaling in Cellular Neural Networks Using Optical Flow  

UK PubMed Central (United Kingdom)

An optical flow gradient algorithm was applied to spontaneously forming networks of neurons and glia in culture imaged by fluorescence optical microscopy in order to map functional calcium signaling...Full Text Available

2010-08-01

399

Light and Dark Controls of Nitrate Reduction in Wheat (Triticum aestivum L.) Protoplasts 1  

UK PubMed Central (United Kingdom)

Protoplasts were isolated from the leaves of nitrate-cultured wheat (Triticum aestivum L. var. Frederick) seedlings. When incubated in the dark, protoplasts accumulated nitrite under...Full Text Available

1982-02-01

400

Isolation of gram-positive rods that resemble but are clearly distinct from Actinomyces pyogenes from mixed wound infections.  

UK PubMed Central (United Kingdom)

Beginning in 1990, gram-positive rods resembling Actinomyces pyogenes were found with increasing frequency in mixed cultures from various infectious processes, most of them from patients with otitis,...Full Text Available

1993-05-01

401

Isolation and Characterization of an H2-Oxidizing Thermophilic Methanogen  

UK PubMed Central (United Kingdom)

A thermophilic methanogen was isolated from enrichment cultures originally inoculated with sludge from an anaerobic kelp digester (55°C). This isolate exhibited a temperature optimum of 55 to...Full Text Available

1983-01-01

402

Intra- and extracellular calcium modulates stereocilia stiffness on chick cochlear hair cells.  

UK PubMed Central (United Kingdom)

Segments of the chick basilar papilla were isolated and maintained in culture medium. The sensory hair bundle of individual hair cells was observed with light microscopy and stimulated with a water...Full Text Available

1994-02-01

403

Interface of culture, insecurity and HIV and AIDS: Lessons from displaced communities in Pader District, Northern Uganda  

UK PubMed Central (United Kingdom)

BackgroundNorthern Uganda unlike other rural regions has registered high HIV prevalence rates comparable to those of urbanized Kampala and the central region. This could be due to...Full Text Available

404

Inoculation of Scytalidium thermophilum in Button Mushroom Compost and Its Effect on Yield  

UK PubMed Central (United Kingdom)

Scytalidium thermophilum isolates in culture, as well as the endogenous strain(s) in mushroom compost, were inactivated at 70°C. This temperature was used to pasteurize composts...Full Text Available

1994-09-01

405

Increase of unsaturated fatty acids under high pressure in a deep-sea bacterium; Shinkai kara bunrisareta taiatsusei biseibutsu DSS12 kabu no baiyo ondo, baiyo atsuryoku to kintai shibosan sosei no henka  

Energy Technology Data Exchange (ETDEWEB)

A cellular membrane exchanges substances into and from the cell and protects the cell interior by maintaining semi-fluidity rather than be being solid. It is known that microorganisms maintain the fluidity in correspondence with varying environmental temperatures by changing and adjusting the composition of fatty acids which constitute the cellular membrane lipids. As part of the studies to elucidate the pressure withstanding mechanism in deep-sea bacteria, this paper investigates what variations the fatty acid composition, which constitutes cellular membranes of the DSS12 strain, a pressure withstanding bacterium growing well under either normal pressure or high pressures, will show under different culturing temperatures and pressures. Culture under low temperatures and culture under high pressures increase content of unsaturated fatty acids including icosapentanoic acid. Culture under high ...

1997-03-01

406

In vitro studies on the adjuvanticity of Brucella fractions.  

UK PubMed Central (United Kingdom)

Two Brucella fractions, the murein-linked fraction PI and the murein-free fraction SF, behave as in vitro adjuvants for primary anti-sheep erythrocyte responses: added to Mishell and Dutton-type cultures...Full Text Available

1982-11-01

407

Immunoquantitative Real-Time PCR for Detection and Quantification of Staphylococcus aureus Enterotoxin B in Foods  

UK PubMed Central (United Kingdom)

A real-time immunoquantitative PCR (iqPCR) method for detection of Staphylococcus aureus enterotoxin B (SEB) was developed and evaluated using both pure cultures and foods. The assay...Full Text Available

2006-10-01

408

Immunolocalization of phospho-S6 kinases: a new way to detect mitosis in tissue sections and in cell culture  

UK PubMed Central (United Kingdom)

During a study on the mTor pathway in the rat kidney we observed a striking increase of the phosphorylation of the S6 kinase in mitosis. In cryostat sections of perfusion-fixed tissue mitotic cells...Full Text Available

2007-02-01

409

Hexadecane mineralization in oxygen-controlled sediment-seawater cultivations with autochthonous microorganisms.  

UK PubMed Central (United Kingdom)

Laboratory studies investigated the influence of dissolved oxygen tension (DOT) on microbial degradation of hexadecane in cultures with sediment-seawater suspensions. With a fermentor system, it was...Full Text Available

1992-09-01

410

H-1152 Effects on Intraocular Pressure and Trabecular Meshwork Morphology of Rat Eyes  

UK PubMed Central (United Kingdom)

AbstractPurposeThe aim of this study was to elucidate the effects of the Rho-kinase inhibitor, H-1152, on cultured human trabecular meshwork (HTM) cells, TM morphology,...Full Text Available

2008-08-01

411

Guided Cell Migration on Microtextured Substrates with Variable Local Density and Anisotropy  

UK PubMed Central (United Kingdom)

This work reports the design of and experimentation with a topographically patterned cell culture substrate of variable local density and anisotropy as a facile and efficient platform to guide...Full Text Available

2009-02-06

412

Germline mutagenesis mediated by Sleeping Beauty transposon system in mice  

UK PubMed Central (United Kingdom)

Following the descovery of its transposition activity in mammalian culture systems, the Sleeping Beauty (SB) transposon has since been applied to achieve germline mutagenesis in mice....Full Text Available

2007-01-01

413

Genome-Wide Transcriptional Response of Chemostat-Cultured Escherichia coli to Zinc  

UK PubMed Central (United Kingdom)

Zinc is an essential trace metal ion for growth, but an excess of Zn is toxic and microorganisms express diverse resistance mechanisms. To understand global bacterial responses to excess Zn, we conducted...Full Text Available

2005-02-01

414

Gendered Technoculture: Sex, Lies, Videotape & Cyberspace  

Science.gov (United States)

What happens in the matrix of gender, technology, representation, and culture? This class will explore the theoretical issues raised within this matrix. We will also make sense of the theories through practical experiences with technologies like computers and cameras.

2004-02-01

415

Flow Cytometry of Human Primary Epidermal and Follicular Keratinocytes  

UK PubMed Central (United Kingdom)

Objective: The aim of this study was to characterize using flow cytometry cultured human primary keratinocytes isolated from the epidermis and hair follicles by different methods. Methods:...Full Text Available

416

Flock infection and transport as sources of salmonellae in broiler chickens and carcasses.  

UK PubMed Central (United Kingdom)

Cultural monitoring was used to determine the incidence and sources of salmonellae in a 4160-bird broiler flock raised on litter in 32 pens. Twenty-five of the pens remained apparently free of salmonellae...Full Text Available

1980-07-01

417

First Culture Isolation of Borrelia lonestari, Putative Agent of Southern Tick-Associated Rash Illness  

UK PubMed Central (United Kingdom)

Southern tick-associated rash illness (STARI) is a Lyme disease-like infection described in patients in the southeastern and south-central United States, where classic Lyme disease is relatively rare....Full Text Available

2004-03-01

418

Evidence that cell surface heparan sulfate is involved in the high affinity thrombin binding to cultured porcine aortic endothelial cells.  

UK PubMed Central (United Kingdom)

It has been postulated that thrombin binds to endothelial cells through, at least in part, cell surface glycosaminoglycans such as heparan sulfate, which could serve as antithrombin cofactor on the...Full Text Available

1985-04-01

419

Evidence That Two Major Replicons Comprise the Genome of Staphylococcus Aureus.  

Science.gov (United States)

In Staphylococcus aureus, a pronounced shift in position of the acriflavin resistance locus was observed when gene order was determined by marker frequency analysis of cells of various ages. In young cells (2-hour culture), acriflavin resistance was mappe...

1967-01-01

420

Evaluation of the Widal tube agglutination test for the diagnosis of typhoid fever among children admitted to a rural hdospital in Tanzania and a comparison with previous studies  

UK PubMed Central (United Kingdom)

BackgroundThe diagnosis of typhoid fever is confirmed by culture of Salmonella enterica serotype Typhi (S. typhi). However, a more rapid, simpler,...Full Text Available

421

Epidermal keratinocytes do not activate peripheral T-cells: interleukin-10 as a possible regulator  

UK PubMed Central (United Kingdom)

The immunogenicity of allogeneic cultured human epidermal keratinocytes (cHEKs) has been studied in several models with contradictory results. We studied human T-cell activation in an in vitro...Full Text Available

2008-11-01

422

Enzyme amplified immunoassay: a novel technique applied to direct detection of Chlamydia trachomatis in clinical specimens.  

UK PubMed Central (United Kingdom)

Endocervical swabs from 212 women and urethral swabs from 100 men were tested by the routine methods for McCoy cell culture and simultaneously by a novel enzyme amplified immunoassay test to detect...Full Text Available

1985-10-01

423

Endometrial biopsy in Holstein-Friesian dairy cows. III. Bacteriological analysis and correlations with histological findings.  

UK PubMed Central (United Kingdom)

This study examines the results of bacterial culture from 159 endometrial biopsy samples from 97 commercial dairy cows and correlations between bacteriological and histological findings. Bacteria were...Full Text Available

1991-04-01

424

Effect of pH and Temperature on Denitrification Gene Expression and Activity in Pseudomonas mandelii?  

UK PubMed Central (United Kingdom)

Pseudomonas mandelii liquid cultures were studied to determine the effect of pH and temperature on denitrification gene expression, which was quantified by quantitative reverse transcription-PCR....Full Text Available

2009-06-01

425

Development of rat CA1 neurones in acute Versus organotypic slices: role of experience in synaptic morphology and activity  

UK PubMed Central (United Kingdom)

Despite their wide use, the physiological relevance of organotypic slices remains controversial. Such cultures are prepared at 5 days postnatal. Although some local circuitry remains intact, they develop...Full Text Available

2003-07-01

426

Detection of cellular responses to toxicants by dielectrophoresis  

UK PubMed Central (United Kingdom)

The dielectrophoretic (DEP) crossover method has been applied to the detection of cell responses to toxicants. Time and dose responses of the human cultured leukemia (HL-60) line were measured...Full Text Available

2002-08-31

427

Detection of Unculturable Bacteria in Periodontal Health and Disease by PCR  

UK PubMed Central (United Kingdom)

Recently developed molecular methods have made it possible to characterize mixed microflora in their entirety, including the substantial numbers of bacteria which do not grow on artificial culture media....Full Text Available

1999-05-01

428

Detection of Chlamydia trachomatis in genital swabs: comparison of commercial and in house amplification methods with culture  

UK PubMed Central (United Kingdom)

AIMS: To evaluate the sensitivity of the Roche Cobas, Roche Amplicor plate kit, ligase chain reaction (LCR), and an in house polymerase chain reaction (PCR) by titration of purified elementary bodies...Full Text Available

1998-08-01

429

Detection and enumeration of toxin-producing Pasteurella multocida with a colony-blot assay.  

UK PubMed Central (United Kingdom)

Colonies of toxin-producing Pasteurella multocida were detected with peroxidase-labeled monoclonal antibodies by a membrane assay. Examination of the specificity of the assay with 29 P. multocida cultures...Full Text Available

1991-07-01

430

Decolorization of reactive dyes by mixed cultures isolated from textile effluent under anaerobic conditions  

British Library Electronic Table of Contents (United Kingdom)

In the present study mixed cultures that could grew in the molasses media were isolated from textile dye effluent and its decolorization activity was studied in a batch system under anaerobic conditions, in order to determine the optimal conditions required for the highest decolorization activity. The optimum pH value for decolorization was determined as 8 for all the dyes tested. In the experiment with pH 8 dye decolorizations by mixed cultures were investigated at about 96.2-1031.3mgl-1 initial dye concentrations. The highest dye removal rates of mixed cultures were 94.9% for Reactive Red RB, 91.0% for Reactive Black B and 63.6% for Remazol Blue at 953.2, 864.9 and 1031.3mgl-1 initial dye concentrations respectively within 24h incubation period. When the Reactive Red RB was used, approxi...

2006-01-01

431

Cytoplasmic heat shock granules are formed from precursor particles and are associated with a specific set of mRNAs.  

UK PubMed Central (United Kingdom)

In heat-shocked tomato cell cultures, cytoplasmic heat shock granules (HSGs) are tightly associated with a specific subset of mRNAs coding mainly for the untranslated control proteins. This messenger...Full Text Available

1989-03-01

432

Cytokinins and Flower Bud Formation in Vitro in Tobacco  

UK PubMed Central (United Kingdom)

Explants from flower stalks of Nicotiana tabacum L. were cultured on different cytokinins to induce flower bud formation. All cytokinins tested except zeatin and zeatin-riboside induced...Full Text Available

1990-03-01

433

Cytochrome c-d regulates developmental apoptosis in the Drosophila retina  

UK PubMed Central (United Kingdom)

The role of cytochrome c (Cyt c) in caspase activation has largely been established from mammalian cell-culture studies, but much remains to be learned about its physiological...Full Text Available

2006-09-01

434

Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator  

UK PubMed Central (United Kingdom)

Curcumin is a natural product currently in human clinical trials for a variety of neoplastic, preneoplastic, and inflammatory conditions. We previously observed that, in cultured cells, curcumin exhibits...Full Text Available

2009-01-08

435

Corticosteroid can alter antigen expression on alveolar macrophages.  

UK PubMed Central (United Kingdom)

Normal healthy volunteers underwent broncho-alveolar lavage and the cells obtained were cultured for 24 h and 48 h, either alone or in the presence of the corticosteroid, Budesonide. Cell differentials...Full Text Available

1991-09-01

436

Comparative Transcriptional and Genomic Analysis of Plasmodium falciparum Field Isolates  

UK PubMed Central (United Kingdom)

Mechanisms for differential regulation of gene expression may underlie much of the phenotypic variation and adaptability of malaria parasites. Here we describe transcriptional variation among culture-adapted...Full Text Available

2009-10-01

437

Cloning and expression of the gene for the Avi-3 antigen of Mycobacterium avium and mapping of its epitopes.  

UK PubMed Central (United Kingdom)

The Avi-3 antigen, which is found only in Mycobacterium avium culture sonic extracts, is species specific and results in strong skin test activity in guinea pigs sensitized with heat-killed M. avium....Full Text Available

1992-03-01

438

Charge compensation for NADPH oxidase activity in microglia in rat brain slices does not involve a proton current  

UK PubMed Central (United Kingdom)

The membrane properties of isolated cultured microglia have been extensively studied but it is important to understand their properties in situ, where they protect the brain against...Full Text Available

2008-09-01

439

Characterization of Cytokinin and Adenine Transport in Arabidopsis Cell Cultures1[OA  

UK PubMed Central (United Kingdom)

Cytokinins are distributed through the vascular system and trigger responses of target cells via receptor-mediated signal transduction. Perception and transduction of the signal can occur at the plasma...Full Text Available

2008-12-01

440

Cell resilience in species lifespans: a link to inflammation?  

UK PubMed Central (United Kingdom)

Species differences in lifespan have been attributed to cellular survival during various stressors, designated here as ‘cell resilience’. In primary fibroblast cultures, cell...Full Text Available

2010-08-01

441

Biosynthetic Pathway of Insect Juvenile Hormone III in Cell Suspension Cultures of the Sedge Cyperus iria1  

UK PubMed Central (United Kingdom)

In most insect species, juvenile hormones regulate critical physiological processes such as metamorphosis and reproduction. In insects, these sesquiterpenoids are synthesized by retrocerebral endocrine...Full Text Available

2001-10-01

442

Biological, Life Course, and Cross-Cultural Studies All point Toward the Value of Dimensional and Developmental Ratings in the Classification of Psychosis  

UK PubMed Central (United Kingdom)

The diagnostic criteria for schizophrenia in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV1)...Full Text Available

2007-07-01

443

Biological Response Modifier Activity of an Exopolysaccharide from Paenibacillus jamilae CP-7  

UK PubMed Central (United Kingdom)

An extracellular polysaccharide was purified from culture supernatants of Paenibacillus jamilae CP-7, a gram-positive bacillus that was isolated from compost prepared with olive mill...Full Text Available

2001-07-01

444

Attachment Stimulates Exopolysaccharide Synthesis by a Bacterium  

UK PubMed Central (United Kingdom)

This study examined the hypothesis that solid surfaces may stimulate attached bacteria to produce exopolymers. Addition of sand to shake-flask cultures seemed to induce exopolymer synthesis by a number...Full Text Available

1993-10-01

445

Apoptosis of human seminoma cells upon disruption of their microenvironment.  

UK PubMed Central (United Kingdom)

One of the main obstacles encountered when trying to culture human seminoma (SE) cells in vitro is massive degeneration of the tumour cells. We investigated whether dissociation of tumour tissue, to...Full Text Available

1996-05-01

446

Albumin interacts specifically with a 60-kDa microvascular endothelial glycoprotein.  

UK PubMed Central (United Kingdom)

Confluent monolayers of microvascular endothelial cells, derived from the rat epididymal fat pad and grown in culture, were radioiodinated by using the lactoper-oxidase method. Their radioiodinated...Full Text Available

1988-09-01

447

A proteomic study of cMyc improvement of CHO culture  

UK PubMed Central (United Kingdom)

BackgroundThe biopharmaceutical industry requires cell lines to have an optimal proliferation rate and a high integral viable cell number resulting in a maximum volumetric recombinant...Full Text Available

448

A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells  

UK PubMed Central (United Kingdom)

Cultured mouse or human embryonic stem (ES) cells provide access to all of the genes required to elaborate the fundamental components and physiological systems of a mammalian cell. Chemical or insertional...Full Text Available

2009-04-01

449

A convenient and sensitive allergy test: IgE crosslinking-induced luciferase expression in cultured mast cells  

UK PubMed Central (United Kingdom)

BackgroundFor the detection of allergen-specific IgE in sera, solid-phase IgE-binding assays like the CAP test are commonly used. Although such immunochemical methods are very sensitive,...Full Text Available

2010-10-01

450

A Nitrate Reductase-less Variant Isolated from Suspension Cultures of Datura innoxia (Mill.) 1  

UK PubMed Central (United Kingdom)

A comparative study has been carried out of the growth of two lines of Datura innoxia (Mill.) cells, designated DI-6 and NR1, their resistance to chlorate, and their ability to assimilate...Full Text Available

1980-10-01

451

3D Hepatic Cultures Simultaneously Maintain Primary Hepatocyte and Liver Sinusoidal Endothelial Cell Phenotypes  

UK PubMed Central (United Kingdom)

Developing in vitro engineered hepatic tissues that exhibit stable phenotype is a major challenge in the field of hepatic tissue engineering. However, the rapid dedifferentiation of...Full Text Available

452

XML schema for atomic and molecular data. Summary report of consultants' meeting  

International Nuclear Information System (INIS)

Advanced developments in computer technologies offer exciting opportunities for new distribution tools and applications in various fields of physics. The convenient and reliable exchange of data is clearly an important component of such applications. Therefore, in 2003, the A+M Data Unit initiated within the collaborative efforts of the DCN (Data Centre Network) a new standard for atomic, molecular and particle surface interaction data exchange (AM'PSI) based on XML (eXtensible Markup Language). A working group composed of staff from the IAEA, NIST, ORNL and Observatoire Paris-Meudon meets biannually to discuss progress made on the XML schema, and to foresee new developments and actions to be taken to promote this standard for AM/PSI data exchange. (author)

2007-12-06

453

Radiation technology, radiation technics and technological dosimetry in the Institute of Isotopes of the Hungarian Academy of Sciences. 1966-1981  

Energy Technology Data Exchange (ETDEWEB)

Pilot-plant irradiation began in Hungary in 1969 with the construction of a high-activity multi-purpose /sup 60/Co facility. Technologies for radiation sterilization, food handling, plastics irradiation as well as chemical dosimetry, semiconductor instrumental dosimetry, computer-based construction and control methods have been developed. Our chlorobenzene dose-meter system is used in Hungary and abroad; as a result of an IAEA-organized dosimetric intercomparison the system was adopted as a reference system. The institute has developed into a basic institute for the reconstruction and re-load of old ..gamma..-facilities as well as it serves for the planning, construction and launching of new ones in Hungary.

1982-01-01

454

Nuclear forensics  

International Nuclear Information System (INIS)

Increasing threat by terrorists for a possible nuclear attack is particularly alarming in recent years. The likelihood of such an event is highly uncertain but cannot be ruled out. The consequence of such an event would be highly disastrous and the implications could be far-reaching both socially and politically. It is feared that significant amount of nuclear weapons materials may be kept under poor security. Therefore, there is a greater demand with utmost priority to curb nuclear terrorism by adapting proper security measures. One of the most important measures is to stop illicit trafficking of nuclear materials which are the source of building nuclear explosive devices. According to the IAEA illicit trafficking database (ITDB) report, a total number of 252 incidents were reported in 2006, of which 150 occurred in 2006 and the remaining 102 had taken place prior to that year, mainly in 2005

2010-11-15

455

Nuclear forensic investigations with a focus on plutonium  

International Nuclear Information System (INIS)

Since the beginning of the 1990s when the first seizures of nuclear material were reported, the IAEA has recorded over 200 cases of illicit trafficking of nuclear materials. Despite the decreasing frequency of nuclear material seizures, particularly the ones involving weapons-grade material, the issue continues to attract public attention and is a reason for concern due to the hazard associated with such materials. Once illicitly trafficked nuclear material has been intercepted, the questions of its intended use and origin are to be addressed. Especially the origin is of prime importance in order to close the gaps and improve the physical protection at the sites where the theft or diversion occurred. To answer these questions, a dedicated nuclear forensics methodology has been developed. In this paper an overview is given on the methodologies used, on the past and on-going developments and on the experience gathered. Some selected examples shall illustrate the ...

2007-10-11

456

IAEA RESEARCH CONTRACTS FIRST ANNUAL REPORT. Technical reports Series No. 4  

Science.gov (United States)

Summaries are included of research contracts which expired prior to Dec. 31, 1960. The contracts were concerned with investigations of: electrophysiological responses of biological systems in nerve cells to irradiation with small doses of ionizing radiations; the mode of the protective action of certain sulfhydryl compounds against radiation effects on the synthesis of deoxyribonucleic acid, using tritium-labeled thymidine; development of a bubble chamber method of monitoring and dosimetry for Low fast neutron fluxes; effects of incorporated radioisotopes on the stability of genetic materials; interrelation of root and leaf absorption of radioisotopes in herbaceous plants; uptake of radioactive wastes by lowland rice from soils contaminated by irrigation water, and decontamination of the rice; and comparison between mutation rates induced by acute and chronic gamma irradiations. (B.O.G.)

1961-01-01

457

Guidebook on design, construction and operation of pilot plants for uranium ore processing  

International Nuclear Information System (INIS)

The design, construction and operation of a pilot plant are often important stages in the development of a project for the production of uranium concentrates. Since building and operating a pilot plant is very costly and may not always be required, it is important that such a plant be built only after several prerequisites have been met. The main purpose of this guidebook is to discuss the objectives of a pilot plant and its proper role in the overall project. Given the wide range of conditions under which a pilot plant may be designed and operated, it is not possible to provide specific details. Instead, this book discusses the rationale for a pilot plant and provides guidelines with suggested solutions for a variety of problems that may be encountered. This guidebook is part of a series of Technical Reports on uranium ore processing being prepared by the IAEA's Division of Nuclear Fuel Cycle and Waste Management. 42 refs, 7 figs, 3 tabs.

458

Exclusion, exemption and clearance in the mining and minerals industry - A review of the concepts from a South African perspective  

International Nuclear Information System (INIS)

The risks from mining and processing of ores is reviewed on a generic basis with particular reference to some of the confusions which can arise due to lack of consistency or common logic in the use of exclusion, exemption and clearance. The difference in exclusion and exemption are challenged by comparing doses received in high background radiation areas and the doses received from a mining practice. The common principle of risk to the human species is not applied consistently. The differences between IAEA recommendations and local regulatory conditions are compared, and the use of exemption levels as clearance levels is considered. A case study on management of mine tailings is presented with special focus on the use of clearance levels. In all areas of review the interpretation of regulation is subject to confusion resulting from inconsistencies which can distort free market economics. (author).

1997-05-06

459

Co-ordinated research programme on isotope-aided studies of the bioavailability of iron and zinc from human diets. Report of the second research co-ordination meeting, Hyderabad, India, 16-20 November 1992  

International Nuclear Information System (INIS)

The Co-ordinated Research Programme (CRP) on ''Isotope-Aided Studies on the Bioavailability of Iron and Zinc from Human Diets'' was initiated by the IAEA in 1990, and presently encompasses participating institutes in 11 countries. A summary of the discussions that took place during thr second Research Co-ordination Meeting held in Hyderabad, India, between 16-20 November 1992, is given in this report together with 12 working papers (progress reports) presented by individual participants. A separate abstract was prepared for each of these papers. Refs, figs and tabs.

1992-11-16

460

Calculation model testing for the case of rcs hot collector rupture inside the horizontal steam generator of VVER-440 NPP  

Energy Technology Data Exchange (ETDEWEB)

The calculations presented are based on RELAP5/MOD2-3 input for VVER 440/213 Bohunice NPP, developed within the framework of IAEA TC Project by an international team of specialists from CSFR, Hungary, Bulgaria and Poland. Project activities were condentrated on input data refinement and testing. Several cases were calculated using the latest version of RELAP5/MOD2 provided by RMA, Albuquerque to investigate some modelling assumptions, such as break location, geometrical representation of secondary circuit piping as well as the effect of deactivation of the signal controlling the SG isolation valves. (2 refs., 21 figs., 2 tabs.).

1993-12-31

461

Calculation model testing for the case of rcs hot collector rupture inside the horizontal steam generator of VVER-440 NPP  

International Nuclear Information System (INIS)

The calculations presented are based on RELAP5/MOD2-3 input for VVER 440/213 Bohunice NPP, developed within the framework of IAEA TC Project by an international team of specialists from CSFR, Hungary, Bulgaria and Poland. Project activities were condentrated on input data refinement and testing. Several cases were calculated using the latest version of RELAP5/MOD2 provided by RMA, Albuquerque to investigate some modelling assumptions, such as break location, geometrical representation of secondary circuit piping as well as the effect of deactivation of the signal controlling the SG isolation valves. (2 refs., 21 figs., 2 tabs.).

1992-09-29

462

An analysis strategy for safeguards use of optical satellite imagery  

International Nuclear Information System (INIS)

This paper outlines conceptual framework for safeguards remote sensing, and suggests a strategy for overcoming the challenges to full exploitation of all types of optical satellite imagery. Since the introduction of commercial open-source high-resolution satellite imagery in 1999, it has become an important tool for verification of declarations, baseline mapping, detection and monitoring of changes and investigation of undeclared activities. Its use is still relatively restricted, but there is a growing demand for wider satellite reconnaissance support, and the Satellite Image Analysis Unit (SIAU) has recently been expanded in response. For a number of reasons, IAEA safeguards use of satellite imagery is largely based on visual interpretation by experienced image analysts of high-resolution monochromatic imagery to monitor and characterize buildings and structures on safeguards sites. The very wide range of remote sensing capabilities could be more fully exploited. ...

2006-10-16

463

An MS-DOS-based program for analyzing plutonium gamma-ray spectra  

Energy Technology Data Exchange (ETDEWEB)

A plutonium gamma-ray analysis system that operates on MS-DOS-based computers has been developed for the International Atomic Energy Agency (IAEA) to perform in-field analysis of plutonium gamma-ray spectra for plutonium isotopics. The program titled IAEAPU consists of three separate applications: a data-transfer application for transferring spectral data from a CICERO multichannel analyzer to a binary data file, a data-analysis application to analyze plutonium gamma-ray spectra, for plutonium isotopic ratios and weight percents of total plutonium, and a data-quality assurance application to check spectral data for proper data-acquisition setup and performance. Volume 3 contains the software listings for these applications.

1989-09-07

464

Uptake and translocation of {sup 137}Cs by Houttuynia cordata (in water culture)  

Energy Technology Data Exchange (ETDEWEB)

The water culture experiment of Houttuynia cordata of the medicinal plant was carried out, and basic study on {sup 137}Cs accumulation characteristic and internal circulation in H. cordata in the fruiting stage was investigated since the flowering season. H. cordata accumulated 80% of {sup 137}Cs absorbed unlike K to the root, rhizome, terminal bud of the underground part for the rhizome reproduction. {sup 137}Cs content to the young leaf, spike, involucre increased in the flowering season. Thereafter, {sup 137}Cs was recirculated to the developing organs in second generations such as the rhizome and bud. (author)

2001-08-01

465

The Integration of Energy Efficiency, Renewable Energy, DemandResponse and Climate Change: Challenges and Opportunities for Evaluatorsand Planners  

Energy Technology Data Exchange (ETDEWEB)

This paper explores the feasibility of integrating energyefficiency program evaluation with the emerging need for the evaluationof programs from different "energy cultures" (demand response, renewableenergy, and climate change). The paper reviews key features andinformation needs of the energy cultures and critically reviews theopportunities and challenges associated with integrating these withenergy efficiency program evaluation. There is a need to integrate thedifferent policy arenas where energy efficiency, demand response, andclimate change programs are developed, and there are positive signs thatthis integration is starting to occur.

2007-05-29

466

Research, Preservation, and Education: An Introduction to Various Heritage Centers, Organizations, and Projects  

British Library Electronic Table of Contents (United Kingdom)

This forum showcases the work of a variety of different heritage-based centers, organizations, and projects dedicated to research, education, and preservation of tangible and intangible forms of cultural heritage. The descriptions of these centers demonstrate the diversity of heritage work being done today. The centers and projects described in the forum vary in their contexts, missions, and outcomes. Highlighted in the forum are preservation organizations, university-based heritage centers, and a global collaborative cultural heritage project. Each organization in the forum provides information about their missions and goals, their approaches or methods to heritage work, and a brief description of some of their initiatives.

2011-01-01

467

Propagation of jarrah (Eucalyptus marginata) by organ and tissue culture  

Energy Technology Data Exchange (ETDEWEB)

Methods are described for the production of callus and subsequent shoot and root induction and multiplication using stamen filaments, nodes of young stems of mature trees or cotyledon petioles. A high frequency of contamination occurred using nodal sections from mature trees, whereas up to 100% sterility was obtained with cotyledons and stamens. The rooting % of shoot cultures from nodes or stamen callus was low compared with that of shoots from seedling callus. Considerable variation was observed between clones from different trees in their ability to produce shoots and roots. 27 references

1982-01-01

468

Mechanism of biodegradation of paraquat by Lipomyces starkeyi  

Energy Technology Data Exchange (ETDEWEB)

The biodegradation of ring-/sup 14/C- and methyl-/sup 14/C-labeled paraquat by the soil yeast Lipomyces starkeyi was studied in vitro. It was found that the degradation of paraquat (acting as a sole source of culture nitrogen) resulted in the accumulation in the extracellular medium of radiolabeled acetic acid. The culture also evolved radiolabeled CO/sub 2/. The results suggest that the degradation of paraquat by L. starkeyi is associated with the integrity of the cell wall and that disruption or removal of the wall results in a complete loss of degradative capability. A mechanism for the degradation of paraquat by this organism is postulated.

1985-05-01

469

Mechanism of biodegradation of paraquat by Lipomyces starkeyi  

International Nuclear Information System (INIS)

The biodegradation of ring-"1"4C- and methyl-"1"4C-labeled paraquat by the soil yeast Lipomyces starkeyi was studied in vitro. It was found that the degradation of paraquat (acting as a sole source of culture nitrogen) resulted in the accumulation in the extracellular medium of radiolabeled acetic acid. The culture also evolved radiolabeled CO_2. The results suggest that the degradation of paraquat by L. starkeyi is associated with the integrity of the cell wall and that disruption or removal of the wall results in a complete loss of degradative capability. A mechanism for the degradation of paraquat by this organism is postulated.

470

In vitro study of plutonium in macrophages  

International Nuclear Information System (INIS)

An in vitro system for studying Pu uptake by, and removal from, macrophages was developed to provide data for the actinide therapy program. We have shown that "2"3"9PuO_2 particle uptake in vitro resembles the process in vivo with respect to the intracellular localization of phagocytized particles. At the end of 7 days of culture of Pu-loaded cells, 54% of the cells were viable even though 71% of the cells in the culture initially contained enough "2"3"9PuO_2 to deliver more than 53 intracellular #alpha#-disintegrations.

1977-05-01

471

Determination of the cell and mucous distribution in the airways of the lung  

International Nuclear Information System (INIS)

Models of the human airways have played a major role in evaluating the health effects of inhaled radionuclides. While models such as those of Weibel (1963) provide data necessary for characterizing deposition of aerosol, they have not characterized the cells at risks in the airspaces. Given the advancements in techniques and study of cell cultures exposed to ionizing radiation there is a need to extrapolate between the simple structures of cell culture systems and the complex architecture of the human airways. The preliminary data in this paper provide a complete characterization of the size and number of cells in the airways and represents a significant advance in our study of the health consequences of exposure to inhaled radionuclides. 26 refs., 2 figs., 4 tabs.

1991-01-01

472

Positive safety features of US nuclear reactors: technical lessons confirmed at Chernobyl. Hearing before the Subcommittee on Energy Research and Production of the Committee on Science and Technology, US House of Representatives, Ninety-Ninth Congress, Second Session, May 14, 1986, No. 138  

Science.gov (United States)

Dr. Rudolf Schulten of West Germany and expert witnesses from national laboratories, utilities, and the nuclear industry testified on reactor safety issues as they relate to the Chernobyl accident and public concern that modern technology has not paid enough attention to public safety. Each of the witnesses contributed safety-related information based on what has been learned from the Soviet incident. Particular focus went to similarities and differences between the Chernobyl and US reactors in safety design and engineering and to the environmental effects of the accident. The N reactor near Richland and a commercial reactor at Fort St. Vrain, Colorado are the only two operating graphite reactors, but neither is a boiling water reactor.

1986-01-01

473

Positive safety features of US nuclear reactors: technical lessons confirmed at Chernobyl. Hearing before the Subcommittee on Energy Research and Production of the Committee on Science and Technology, US House of Representatives, Ninety-Ninth Congress, Second Session, May 14, 1986, No. 138  

International Nuclear Information System (INIS)

Dr. Rudolf Schulten of West Germany and expert witnesses from national laboratories, utilities, and the nuclear industry testified on reactor safety issues as they relate to the Chernobyl accident and public concern that modern technology has not paid enough attention to public safety. Each of the witnesses contributed safety-related information based on what has been learned from the Soviet incident. Particular focus went to similarities and differences between the Chernobyl and US reactors in safety design and engineering and to the environmental effects of the accident. The N reactor near Richland and a commercial reactor at Fort St. Vrain, Colorado are the only two operating graphite reactors, but neither is a boiling water reactor.

474

Implementing 10 CFR Part 830 Subpart B at WIPP  

Energy Technology Data Exchange (ETDEWEB)

Implementation of Title 10 Code of Federal Regulations Part 830, Subpart B Nuclear Safety Management (1) was accomplished at the Waste Isolation Pilot Plant (WIPP) in a timely and efficient manner. The primary reason the transition went smoothly was that the existing safety analysis was relatively new, initially developed in 1995, and written in accordance with the safe harbor document DOE-STD-3009 (2). The WIPP Safety Analysis Report (SAR) (3) is kept up-to-date with the unreviewed safety question (USQ) process and thorough oversight and input provided by DOE-Carlsbad Field Office (CBFO) documented in the annual safety evaluation report (SER) process.

2002-02-26

475

Gas-cooled fast reactor safety - and overview and status of the U.S. program  

International Nuclear Information System (INIS)

In the revised GCFR Safety Program Plan a quantitative risk limit line has been adopted to establish requirements for the safety related functions and systems. The risk limit line is derived from an interpretation of NRC established licensing requirements, including those for LMFBR's. Multiple barriers to the progression of accident sequences are defined in the form of six Lines of Protection (LOPs). LOPs-1 to 3 are dedicated to accident prevention and represent the normal operating systems, the dedicated safety systems and the inherent design features, respectively. LOPs-4 to 6 are dedicated to the mitigation of core melt accident consequences and include in-vessel accident containment, secondary containment integrity and radiological attenuation, respectively. Cumulative frequency limits and consequence limits are established for each LOP. Design features associated with each LOP are described and the results of ...

1981-01-01

476

Draft Regulatory Rule-making for On-line Maintenance of Nuclear Power Plants  

International Nuclear Information System (INIS)

Internationally, on-line maintenance (OLM) of nuclear power plants under the operation is prevailed to enhance nuclear safety and economics. In recent years, Korea Hydro and Nuclear Power Co. Ltd. (KHNP) is eager to apply OLM. Ministry of Education, Science and Technology (MEST) has established the related technology development program as an item of 'Overall Planning on Nuclear Safety(2010-2014)' through acceptance to the request of KHNP in 2009. OLM is defined as maintenance that is performed with the main generator connected to the grid. In other words, it means a preventive maintenance to be implemented during the allowable outage time (AOT) with ignoring inoperability of safety-related equipment listed in the technical specifications. The Korea Institute of Nuclear Safety (KINS) is developing the assessment technology of safety concerns for OLM under the auspices of MEST. Draft ...

2010-10-01

477

Tests for the diagnosis of Clostridium difficile infection: the next generation.  

Science.gov (United States)

Clostridium difficile (C. difficile) causes 25-30% of cases of antibiotic associated diarrhea and most cases of pseudomembranous colitis. Patients presenting with diarrhea after hospitalization for 3 or more days should be tested for C. difficile. There are many options available for testing, each of which has inherent advantages and disadvantages. Most laboratories perform toxin testing using an enzyme immunoassay method. In general these tests have sensitivities ranging from 60 to 70% and specificities of 98%. When using these methods, symptomatic patients with negative tests should be tested by another more sensitive method. Until recently, cell culture cytotoxicity neutralization assays (CCNAs) were considered the gold standard in the U.S. A two-step algorithm using an EIA for glutamate dehydrogenase detection followed by testing positives using CCNA, offered an improved alternative until the availability of molecular assays. Although early studies that ...

2011-03-03

478

Regulation of sulfated glycosaminoglycan production by prostaglandin E2 in cultured lung fibroblasts  

Energy Technology Data Exchange (ETDEWEB)

Prostaglandin E2 (PGE2) has been shown to increase the synthesis of hyaluronic acid in cultured fibroblasts by increasing the activity of hyaluronate synthetase, a group of plasma membrane-bound synthetic enzymes. We examined whether PGE2 also increased the activity of those enzyme systems involved in the synthesis of sulfated glycosaminoglycan in the human embryonic lung fibroblast. Exposure of cells to PGE2 resulted in dose-dependent increases in glucosamine incorporation into all sulfated glycosaminoglycan subtypes. PGE2 at 10(-7) mol/L increased total glycosaminoglycan per dish to 21.6 +/- 3.1 micrograms versus 12.0 +/- 2.5 micrograms in control untreated cultures. Stimulation of endogenous PGE2 production by bradykinin had a similar effect on glycosaminoglycan synthesis. To examine whether PGE2 affected sulfated glycosaminoglycan protein core production, cells were labeled with tritiated glucosamine in the presence of cycloheximide. Under ...

1989-08-01

479

Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations  

Science.gov (United States)

With the advent of subgenomic hepatitis C virus (HCV) replicons, studies of the intracellular steps of the viral replication cycle became possible. These RNAs are capable of self-amplification in cultured human hepatoma cells, but save for the genotype 2a isolate JFH-1, efficient replication of these HCV RNAs requires replication enhancing mutations (REMs), previously also called cell culture adaptive mutations. These mutations cluster primarily in the central region of non-structural protein 5A (NS5A), but may also reside in the NS3 helicase domain or at a distinct position in NS4B. Most efficient replication has been achieved by combining REMs residing in NS3 with distinct REMs located in NS4B or NS5A. However, in spite of efficient replication of HCV genomes containing such mutations, they do not support production of infectious virus particles. By using the genotype 1b isolate Con1, in this study we show that REMs interfere with HCV ...

2009-06-12

480

Human Mammary Luminal Epithelial Cells Contain Progenitors to Myoepithelial Cells  

Energy Technology Data Exchange (ETDEWEB)

The origin of the epithelial and myoepithelial cells in the human breast has not been delineated. In this study we have addressed whether luminal epithelial cells and myoepithelial cells are vertically connected, i.e., whether one is the precursor for the other. We used a primary culture assay allowing preservation of basic phenotypic traits of luminal epithelial and myoepithelial cells in culture. The two cell types were then separated immunomagnetically using antibodies directed against lineage-specific cell surface antigens into at best 100% purity. The cellular identity was ascertained by cytochemistry, immunoblotting, and 2-D gel electrophoresis. Luminal epithelial cells were identified by strong expression of cytokeratins 18 and 19 while myoepithelial cells were recognized by expression of vimentin and {alpha}-smooth muscle actin. We used a previously devised culture medium (CDM4) that allows vigorous expansion of ...

1999-02-01

481

Growth-related variations in the glycosaminoglycan synthesis of ultraviolet light-induced murine cutaneous fibrosarcoma cells  

Energy Technology Data Exchange (ETDEWEB)

Glycosaminoglycan synthesis was studied in cell populations of ultraviolet light-induced murine cutaneous fibrosarcoma cells under conditions of varying growth rates in vitro. After labeling with the precursors, /sup 3/H-glucosamine and /sup 35/SO/sub 4/, sulfated glycosaminoglycans recoverable by direct proteolysis of the culture monolayers increased approximately 5-fold on a per cell basis from sparsely populated, exponential cell cultures (greater than 85% of cells in S, G2, or M phases) to stationary cultures inhibited by high cell density (greater than 50% of cells in G1). Within this cell surface-associated material, the relative ratio of heparan sulfate to the chondroitin sulfates was approximately 60/40% under conditions of exponential growth; in the growth-arrested cultures, the reverse ratio was found. The substratum attached material, obtained from the flask surface after ethyl glycol ...

1985-08-01

482

Summary of the report of the Senior Committee on Environmental, Safety, and Economic Aspects of Magnetic Fusion Energy  

Energy Technology Data Exchange (ETDEWEB)

The Senior Committee on Environmental, Safety, and Economic Aspects of Magnetic Fusion Energy (ESECOM) has assessed magnetic fusion energy's prospects for providing energy with economic, environmental, and safety characteristics that would be attractive compared with other energy sources (mainly fission) available in the year 2015 and beyond. ESECOM gives particular attention to the interaction of environmental, safety, and economic characteristics of a variety of magnetic fusion reactors, and compares them with a variety of fission cases. Eight fusion cases, two fusion-fission hybrid cases, and four fission cases are examined, using consistent economic and safety models. These models permit exploration of the environmental, safety, and economic potential of fusion concepts using a wide range of possible materials choices, power densities, power conversion schemes, and fuel ...

1987-09-10

483

Safety analysis practices for the dense storage of RBMK spent fuel and improved technology for the long term storage of spent fuel in water pools  

International Nuclear Information System (INIS)

The paper discusses the safety problems connected with the conversion to dense storage of RBMK-1000 spent fuel in reactor cooling pools and independent storage facilities. Recourse to dense storage has been made for a number of reasons, among which are the absence of spent fuel shipments from the nuclear power plant site, prolongation of storage time and a partial change in storage conditions. Increasing the storage density per unit volume of the storage facility and turning to new technical procedures (as against the basic design) call for further investigation of safety problems. The safety assessment of the dense storage mode includes: (1) Selecting a list of initiating events for design basis and unforeseeable accidents; (2) Assessing dense storage safety under normal as well as design basis accident conditions; (3) Safety analysis and development of measures to compensate for ...

1995-08-01

484

DOE explosives safety manual  

Energy Technology Data Exchange (ETDEWEB)

The Department of Energy (DOE) policy requires that all activities be conducted in a manner that protects the safety of the public and provides a safe and healthful workplace for employees. DOE has also prescribed that all personnel be protected in any explosives operation undertaken. The level of safety provided shall be at least equivalent to that of the best industrial practice. The risk of death or serious injury shall be limited to the lowest practicable minimum. DOE and contractors shall continually review their explosives operations with the aim of achieving further refinements and improvements in safety practices and protective features. This manual describes the Department's explosive safety requirements applicable to operations involving the development, testing, handling, and processing of explosives or assemblies containing explosives. It is intended to reflect the state-of-the-art ...

1990-05-01

485

The role of networking for nuclear education  

International Nuclear Information System (INIS)

Nuclear knowledge is the basis for almost all nuclear activities, and education and training are the most fundamental means to transfer knowledge from one generation to the next. Understanding means and trends in knowledge transfer through education and training thus deserves a closer examination. In the past years, a number of trends and questions in nuclear knowledge, education and training have emerged. With declining student enrolment numbers and a general stagnation of the use of nuclear power in some of the IAEA's Member States, the issue of a slow erosion of the knowledge base and the possibility of loosing knowledge has become increasingly important, in particular if seen against the background of a possible renaissance of nuclear power in the future. In other Member States, an expansion of nuclear power is expected, with a corresponding need for human resources. As a result, in many Member States education and training of the next generation and succession ...

2004-10-01

486

Future needs and requirements for AMS "1"4C standards and reference materials  

International Nuclear Information System (INIS)

"1"4C measurement uses a number of standards and reference materials with different properties. Historically the absolute calibration of "1"4C measurement was tied to 1890 wood, through the 'primary' standard of NBS-OxI (produced by the National Bureau of Standards, now NIST - National Institute of Standards and technology) subsequently replaced by NBS-OxII. These are both internationally calibrated and certified materials, whose "1"4C activities are known absolutely. A second tier of materials, often called secondary standards or reference materials, and including internationally recognised materials such as ANU-sucrose (now also IAEA-C6), Chinese - sucrose and the IAEA C1-C6 series, augmented by additional oxalic acid samples are also used routinely. The activity of these materials has been estimated from large numbers of measurements made by many laboratories. Recently, further natural materials from the Third and Fourth International ...

2004-08-01

487

PSA methodology including new design, operational and safety factors, 'Level of recognition of phenomena with a presumed dominant influence upon operational safety' (failures of conventional as well as non-conventional passive components, dependent failures, influence of operator, fires and external threats, digital control, organizational factors)  

International Nuclear Information System (INIS)

The document represents a specific type of discussion of existing methodologies for the creation and application of probabilistic safety assessment (PSA) in light of the EUR document summarizing requirements placed by Western European NPP operators on the future design of nuclear power plants. A partial goal of this discussion consists in mapping, from the PSA point of view, those selected design, operational and/or safety factors of future NPPs that may be entirely new or, at least, newly addressed. Therefore, the terms of reference for this stage were formulated as follows: Assess current level of knowledge and procedures in the analysis of factors and phenomena with a dominant influence upon operational safety of new generation reactors, especially in the following areas: (1) Phenomenology of failure types and mechanisms and reliability of conventional passive safety system components; (2) ...

488

Regulatory view of the close-out of the uranium ore mine Zirovski Vrh  

International Nuclear Information System (INIS)

The production of the uranium mine Zirovski Vrh ceased in 1990. The main remaining problem of the remadiation are mine and mill tailings. The uranium mine Zirovski Vrh has one mill tailings site Borst and one waste pile Jazbec. According to the Act on protection against ionising radiation and nuclear safety which was adopted by the Parliament in 2002, they are classified as radiation facilities. Slovenian Nuclear Safety Administration (SNSA) is authorised for issuing a mandatory consent to mining work. The SNSA prepared the initial proposal of content of the safety report for the mine waste pile Jazbec. In 2005, according to the detailed content of this document, the public company Zirovski Vrh Ltd prepared the safety report which was examined by an authorised expert for radiation and nuclear safety. After a careful revision of the safety evaluation report, the ...

2005-09-05

489

Regulatory requirements for design of safety related computer based control Systems in Indian PHWRs: case study of DPHS-PCS for TAPP-3 and 4  

International Nuclear Information System (INIS)

Computer based control systems for safety related applications in nuclear power plants have to meet not only the functional, performance and interface requirements, they in addition, have to meet regulatory requirements like enhanced reliability, safety and security and should provide fault tolerance, diagnostics and self-supervision. The control system architecture, hardware design and software design should meet requirements as specified in design code and guides of AERB. The Dual Processor Hot Standby Process Control System (DPHS-PCS) for TAPP-3 and 4 is a safety related (Class- IB) system. DPHS-PCS regulates PHT pressure, Pressuriser pressure, Pressuriser level, Bleed condenser pressure, Bleed condenser level and Steam generator pressure. The performance, reliability and safety requirements of this control system are met by employing a fault tolerant computer configuration developed for this purpose ...

2005-03-01

490

Optimal inspection and replacement periods of the safety system in Wolsung Nuclear Power Plant Unit 1 with an optimized cost perspective  

Energy Technology Data Exchange (ETDEWEB)

In this work, a model for determining the optimal inspection and replacement periods of the safety system in Wolsung Nuclear Power Plant Unit 1 is developed, which is to minimize economic loss caused by inadvertent trip and the system failure. This model uses cost benefit analysis method and the part for optimal inspection period considers the human error. The model is based on three factors as follows: (i) The cumulative failure distribution function of the safety system, (ii) The probability that the safety system does not operate due to failure of the system or human error when the safety system is needed at an emergency condition and (iii) The average probability that the reactor is tripped due to the failure of system components or human error. The model then is applied to evaluate the safety system in Wolsung Nuclear Power Plant Unit 1. The optimal replacement periods which ...

1996-01-01

491

Improving safety and quality: how can education help?  

Science.gov (United States)

National efforts to improve the quality and safety of health care present challenges for medical education and training. Today's doctors need to be skilled communicators who know how to identify, prevent and manage adverse events and near misses, how to use evidence and information, how to work safely in a team, how to practise ethically, and how to be workplace teachers and learners. These competencies (knowledge, skills and attitudes) are set out in the National Patient Safety Education Framework (NPSF) of the Australian Council for Safety and Quality in Health Care. The NPSF is designed to help medical schools, vocational colleges, health organisations and private practitioners develop curricula to enable health professionals to work safely. The NPSF describes what doctors (depending on their level of knowledge and experience) can do to demonstrate competencies in a range of quality and safety ...

2006-05-15

492

Foundations  

Energy Technology Data Exchange (ETDEWEB)

This Health and Safety (HSE) document offers technical information on the design of foundations for supports in offshore installations, and relates particularly to the North Sea. It is based largely on guidance offered earlier in Section 20 of the Fourth Edition of the Health and Safety Executive's 'Offshore Installations; Guidance on Design, Construction and Certification', which was withdrawn in 1998. The document contains a general section on foundations and the rest of the document comprises sections on: (a) piled foundations (planning, problems, pile make-up, steel stresses, design of pile foundations, axial pile capacity, factors of safety for piled foundations, load-deflection of piles, and piles for tethered buoyant structures); (b) foundations for gravity structures (foundation types, loads and reactions during installation, operating loads and reactions, foundation problems, cyclic load ...

2002-07-01

493

Definition and means of maintaining the criticality detectors and alarms portion of the PFP safety envelope  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this document is to provide the definition and means of maintaining the Safety Envelope (SE) related to the Criticality Alarm System (CAS). This document provides amplification of the Limiting Condition for Operation (LCO) described in the Plutonium Finishing Plant (PFP) Operational Safety Requirements (OSR), WHC-SD-CP-OSR-010, Rev. 0, 1994, Section 3.1.2, Criticality Detectors and Alarms. This document, with its appendices, provides the following: (1) System functional requirements for determining system operability (Section 3); (2) A list of annotated system block diagrams which indicate the safety envelope boundaries (Appendix C); (3) A list of the Safety Class 1 and 2 Safety Envelope (SC-1/2 SE) equipment for input into the Master Component Index (Appendix B); (4) Functional requirements for individual SC-1/2 SE components, including appropriate setpoints and ...

1997-05-13

494

Characteristics of safety critical organizations . work psychological perspective  

International Nuclear Information System (INIS)

This book deals with organizations that operate in high hazard industries, such as the nuclear power, aviation, oil and chemical industry organisations. The society puts a great strain on these organisations to rigorously manage the risks inherent in the technology they use and the products they produce. In this book, an organisational psychology view is taken to analyse what are the typical challenges of daily work in these environments. The analysis is based on a literature review about human and organisational factors in safety critical industries, and on the interviews of Finnish safety experts and safety managers from four different companies. In addition to this, personnel interviews conducted in the Finnish nuclear power plants are utilised. The authors come up with eight themes that seem to be common organizational challenges cross the industries. These include e.g. how does the personnel understand the risks and ...

495

Regulation of lipoprotein lipase in primary cultures of isolated human adipocytes  

Energy Technology Data Exchange (ETDEWEB)

To study the regulation of adipose tissue lipoprotein lipase (LPL) in human adipocytes, omental adipose tissue was obtained from healthy subjects and digested in collagenase. The isolated adipocytes thus obtained were suspended in Medium 199 and cultured at 37 degrees C. Cell viability was demonstrated in adipocytes cultured for up to 72 h by constancy of cell number, cell size, trypan-blue exclusion, and specific /sup 125/I-insulin binding. In addition, chloroquine induced an increase in cell-associated /sup 125/I-insulin at 24, 48, and 72 h after preparation. Thus, isolated adipocytes retained their ability to bind, internalize, and degrade insulin. LPL was measured as activity secreted into the culture medium (CM), released from cells by heparin (HR), and extracted from cell digests. A broad range of heparin concentrations produced a prompt release of LPL from a rapidly replenishable pool of cellular activity. When cells ...

1985-01-01

496

Production of Shiga-like toxins by Escherichia coli O157:H7 can be influenced by the neuroendocrine hormone norepinephrine.  

Science.gov (United States)

To examine whether the neuroendocrine hormone norepinephrine may influence the production of the Shiga-like toxins (SLTs), several Escherichia coli O157:H7 clinical isolates were grown in the presence or absence of norepinephrine. An in vitro culture system consisting of low (<1500 colony-forming units/ml) initial concentrations of inocula into a serum-based medium was used to more closely approximate in vivo conditions. The growth of all isolates was increased several logs in the presence of norepinephrine, as compared with the growth in controls, during a 24-hour growth period. Controls included additional dextrose as well as the use of the norepinephrine metabolite normetanephrine, which contains one more methyl group than norepinephrine and hence would serve as a better energy source for growth if the effect were solely nutritionally mediated. During the 24 hours of growth, the production of cell-associated SLT-I on a protein-equivalent basis was shown to be ...

1996-10-01

497

Effect of temperature on the development of Steinernema carpocapsae and Steinernema feltiae (Nematoda: Rhabditida) in liquid culture.  

Science.gov (United States)

For commercial use of the entomopathogenic nematodes Steinernema carpocapsae and Steinernema feltiae in biological control of insect pests, they are produced in liquid culture on artificial media pre-incubated with their symbiotic bacteria Xenorhabdus nematophila and Xenorhabdus bovienii, respectively. After 1 day of the bacterial culture, nematode dauer juveniles (DJs) are inoculated, which recover development. The adult nematodes produce DJ offspring, which are harvested and can be sprayed. This study determined optimal temperatures to obtain high DJ progeny within a short process time. Temperatures assessed were 23 degrees C, 25 degrees C, 27 degrees C, and 29 degrees C for S. carpocapsae and 20 degrees C, 23 degrees C, 25 degrees C, and 27 degrees C for S. feltiae. The recovery of inoculated DJs was hardly affected and was reduced only in S. carpocapsae at 29 degrees C. The fecundity (eggs in uterus) in S. carpocapsae reached a maximum at ...

2009-05-20

498

Cultured epidermal allografts as biological wound dressings.  

Science.gov (United States)

Recent advances in cell culture technology permit the generation of large stratified epithelial sheets appropriate for wound coverage. Autografts (sheets prepared from the patient's own skin) have proven life-saving in the treatment of large third-degree burns and have been successfully employed in the management of chronic ulcers. Allografts (sheets prepared from the skin of an unrelated donor) have also been used. In our experience, cultured allografts derived from neonatal foreskin provide a potent stimulus to healing in a variety of partial thickness wounds. Their application is a simple outpatient procedure which involves no discomfort for the patient. In contrast to autografting, no biopsy is necessary and use of cultured allogenic cells permits immediate grafts availability and possibility of stockpiling and preserving grafts for future use. Preparation of epithelial sheets suitable for grafting is also faster and ...

1991-01-01