WorldWideScience

Sample records for himalayas selection potential

  1. Identification and bioactive potential of endophytic fungi isolated from selected plants of the Western Himalayas

    OpenAIRE

    Qadri, Masroor; Johri, Sarojini; Shah, Bhahwal A; Khajuria, Anamika; Sidiq, Tabasum; Lattoo, Surrinder K; Abdin, Malik Z.; Riyaz-Ul-Hassan, Syed

    2013-01-01

    This study was conducted to characterize and explore the endophytic fungi of selected plants from the Western Himalayas for their bioactive potential. A total of 72 strains of endophytic fungi were isolated and characterized morphologically as well as on the basis of ITS1-5.8S-ITS2 ribosomal gene sequence acquisition and analyses. The fungi represented 27 genera of which two belonged to Basidiomycota, each representing a single isolate, while the rest of the isolates comprised of Ascomycetous...

  2. Identification and bioactive potential of endophytic fungi isolated from selected plants of the Western Himalayas.

    Science.gov (United States)

    Qadri, Masroor; Johri, Sarojini; Shah, Bhahwal A; Khajuria, Anamika; Sidiq, Tabasum; Lattoo, Surrinder K; Abdin, Malik Z; Riyaz-Ul-Hassan, Syed

    2013-12-01

    This study was conducted to characterize and explore the endophytic fungi of selected plants from the Western Himalayas for their bioactive potential. A total of 72 strains of endophytic fungi were isolated and characterized morphologically as well as on the basis of ITS1-5.8S-ITS2 ribosomal gene sequence acquisition and analyses. The fungi represented 27 genera of which two belonged to Basidiomycota, each representing a single isolate, while the rest of the isolates comprised of Ascomycetous fungi. Among the isolated strains, ten isolates could not be assigned to a genus as they displayed a maximum sequence similarity of 95% or less with taxonomically characterized organisms. Among the host plants, the conifers, Cedrus deodara, Pinus roxburgii and Abies pindrow harbored the most diverse fungi, belonging to 13 different genera, which represented almost half of the total genera isolated. Several extracts prepared from the fermented broth of these fungi demonstrated strong bioactivity against E. coli and S. aureus with the lowest IC(50) of 18??g/ml obtained with the extract of Trichophaea abundans inhabiting Pinus sp. In comparison, extracts from only three endophytes were significantly inhibitory to Candida albicans, an important fungal pathogen. Further, 24 endophytes inhibited three or more phytopathogens by at least 50% in co-culture, among a panel of seven test organisms. Extracts from 17 fungi possessed immuno-modulatory activities with five of them showing significant immune suppression as demonstrated by the in vitro lymphocyte proliferation assay. This study is an important step towards tapping the endophytic fungal diversity from the Western Himalayas and assessing their bioactive potential. Further studies on the selected endophytes may lead to the isolation of novel natural products for use in medicine, industry and agriculture. PMID:23420270

  3. Permafrost in the Himalayas: specific characteristics, evolution vs. climate change and impacts on potential natural hazards

    Science.gov (United States)

    Fort, Monique

    2015-04-01

    Mountain environments are very sensitive to climate change, yet assessing the potential impacts of these changes is not easy because of the complexity and diversity of mountain systems. The Himalayan permafrost belt presents three main specificities: (1) it develops in a geodynamically active mountain, which means that the controlling factors are not only temperature but also seismo-tectonic activity; (2) due to the steepness of the southern flank of the Greater Himalaya and potential large scale rock failures, permafrost evidence manifests itself best in the inner valleys and on the northern, arid side of the Himalayas (elevations >4000m); (3) the east-west strike of the mountain range creates large spatial discontinuity in the "cold" belt, mostly related to precipitation nature and availability. Only limited studies have been carried to date, and there is no permanent "field laboratory", nor continuous records but a few local studies. Based on preliminary observations in the Nepal Himalayas (mostly in Mustang and Dolpo districts), and Indian Ladakh, we present the main features indicating the existence of permafrost (either continuous or discontinuous). Rock-glaciers are quite well represented, though their presence may be interpreted as a combined result from both ground ice and large rock collapse. The precise altitudinal zonation of permafrost belt (specifying potential permafrost, probable permafrost, observed permafrost belts) still requires careful investigations in selected areas. Several questions arise when considering the evolution of permafrost in a context of climate change, with its impacts on the development of potential natural hazards that may affect the mountain population. Firstly, permafrost degradation (ground ice melting) is a cause of mountain slope destabilization. When the steep catchments are developed in frost/water sensitive bedrock (shales and marls) and extend to high elevations (as observed in Mustang or Dolpo), it would supply more mass-wasting and debris-flow events and may directly threat the infrastructures recently built to unlock these remote areas. Secondly, acceleration of permafrost degradation might also affect the steepest rock walls (as in Khumbu, Manang and Mustang Himals) and cause rock avalanches that could impact nearby settlements, as suggested by relicts of past events. Lastly, ground ice is a hidden source of water in areas without permanent glacial ice. In a context of global warming this non-renewable resource would be depleted and no longer available for the population living in these areas, all the more as growing tourism activities are increasing the demand for water consumption that may conflicts with irrigated agricultural uses down valley. More in-situ observations and long-term monitoring studies should certainly be useful to understand climate trends hence permafrost evolution and their consequences in order to help mountain populations of the cold, arid Himalayas to adjust to progressive changes in their environmental conditions and resources.

  4. Hot springs and the geothermal energy potential of Jammu & Kashmir State, N.W. Himalaya, India

    Science.gov (United States)

    Craig, J.; Absar, A.; Bhat, G.; Cadel, G.; Hafiz, M.; Hakhoo, N.; Kashkari, R.; Moore, J.; Ricchiuto, T. E.; Thurow, J.; Thusu, B.

    2013-11-01

    India has an estimated geothermal power potential of 10,600 MWe, but this potential is entirely undeveloped at present. The 'Geothermal Atlas of India' prepared by the Geological Survey of India (GSI) in 1991 describes some 340 hot spring sites and identifies more than 300 sites with geothermal potential in at least seven key geothermal provinces throughout India. There are more than 20 hot spring sites in Jammu & Kashmir State, mainly in the Chenab Valley in the Lesser/Central Himalaya, the Kashmir Valley and in the High Himalaya region of Ladakh. At least three localities in the Ladakh region - Chamuthang and Puga in the Indus valley and Panamik in the Nubra Valley - are considered to have geothermal power generation potential of between 3 and > 20 MWe.

  5. Hazard Assessment of Glacial Lake Outburst Flood and Potential of ICTs for Coping: A Case of Eastern Himalaya of Nepal

    Science.gov (United States)

    Bhattarai, D. R.; Pradhananga, D.

    2014-12-01

    Alarming rate of retreat of glaciers and formation of glacial lakes in higher elevation of Nepal Himalaya has been reported to be related with the pronounced atmospheric temperature rise in the region. Glacier Lake Outburst Floods (GLOF) are the growing climate induced hazards in the Himalaya increasing the vulnerability of community living in the mountain valley, and the fragile ecosystem. This study tried to come up with the potential impacts from glacial lake outburst flood (GLOF) in highland of eastern region of Nepal and potential role of Information Communication Technologies (ICT) in coping. I analyzed the trend of climatic pattern (temperature and precipitation) of the Eastern Himalaya Region of Nepal available from Department of Hydrology and Meteorology (DHM), Government of Nepal, and also prepared the latest location map of the glacial lakes using google earth and ArcGIS application in the highland of the Kanchanjungha Conservation Area of the region. Tiptala glacial lake, located at an elevation of 4950 masl, within the conservation area, was selected for the GLOF hazard assessment. I used semi-structured questioner survey and key informants interviews in the community living below the lake in the highland of the study area in order to assess the potential hazard of GLOF. Analysis shows the increasing trend of atmospheric temperature in the region. With the varying sizes, 46 glacial lakes were located in the region, which covers over 2.57 sq. km in total. Though the larger portion of the downstream area of the Tiptala glacial lake fall in the remote location away from major residential area, few villages, major pasture lands for Yaks, foot trails, and several bridges across the Tamor River below the lake are in risk of GLOF. Poor access due to extreme geographical remoteness and capacity to afford the modern technologies in the community is seen as the major limiting factor to the knowledge and information about the climate change and related impacts. Modern ICTs has high potential to reduce the risk of climate related hazards in the remote area by information dissemination and awareness.

  6. Carbon Stock Potential of Oak and Pine Forests in Garhwal Region in Indian Central Himalayas

    Directory of Open Access Journals (Sweden)

    Nanda Nautiyal

    2013-05-01

    Full Text Available Oak (Quercus leucotichophora and pine (Pinus roxburghii are the two most dominant forest types occurring in Indian Central Himalayas. CO2 mitigation potential of these two forest types was observed in the present study. Carbon stock densities for AGTB, BB, LHG, DWS, AGSB and SOC were estimated and higher values were recorded in oak forest stands. Total carbon density estimated was 2420.54 Mg/ha for oak forest of Gopeshwar and 986.93 Mg/ha for pine forest of Nandprayag. CO2 mitigation potential of oak forest of Gopeshwar was recorded to be 8,713.94 CO2e and of pine forests 3552.95 CO2e.

  7. A Multidimensional Poverty Measure for the Hindu Kush–Himalayas, Applied to Selected Districts in Nepal

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    Jean-Yves Gerlitz

    2015-08-01

    Full Text Available Approximately 211 million people live in the Hindu Kush–Himalaya region. Although poverty levels in this region are high, there is a lack of cohesive information on the socioeconomic status of its populations that would enable decision-makers to understand different manifestations of poverty and design effective poverty alleviation programs. Hence, the International Centre for Integrated Mountain Development (ICIMOD, in consultation with international and regional partners, has developed the Multidimensional Poverty Measure for the Hindu Kush–Himalayas (MPM-HKH. This measure aims to identify and describe poor and vulnerable households across the Hindu Kush–Himalaya region—which is predominantly rural and mountainous and covers several of the world’s least developed countries—in a consistent manner. This article documents how the MPM-HKH was developed and demonstrates the utility of this approach, using Nepal as an example, by analyzing household survey data from 23 districts. The analysis gives important clues about differences in the intensity and composition of multidimensional poverty across these locations, which highlights the need for location-specific poverty alleviation strategies. The findings should help decision-makers to identify areas of intervention and choose the best measures to reduce poverty.

  8. Great earthquakes, seismicity gaps and potential for earthquake disaster along the Himalaya plate boundary

    Science.gov (United States)

    Khattri, K. N.

    1987-06-01

    Analysis of the space-time patterns of seismicity in the Himalaya plate boundary has established the existence of three seismic gaps: (1) The "Kashmir gap" lying west of the 1905 Kangra earthquake; (2) the "Central gap", situated between the 1905 Kangra and the 1934 Bihar earthquakes; (3) the "Assam gap" between the 1897 and 1950 Assam earthquakes. This study has shown that the above great earthquakes were preceded as well as followed by long periods (? 19 years) of decreased levels of seismic activity in the epicentral regions. Remarkable decrease in the seismicity following the year 1970 has been observed in the western half of the Central gap as well as in the Assam gap. Local seismic investigation in the Assam gap confirms this feature and the seismicity suggests the existence there of an asperity. The local seismic investigations in Garhwal Himalaya have shown that the small earthquakes are confined to the upper 6-8 km of the crust and may have strike-slip motions. These earthquakes occur in a region where teleseismically recorded events were few.

  9. Seedling growth and survival of selected wild edible fruit species of the Sikkim Himalaya, India

    Science.gov (United States)

    Sundriyal, Manju; Sundriyal, R. C.

    2005-07-01

    In the Sikkim Himalaya, an enormous variety of wild growing plants are exploited at large scale for collection of their edible parts, of which six most prominently utilized fruit species (viz., Baccaurea sapida, Diploknema butyracea, Elaeagnus latifolia, Eriolobus indica, Machilus edulis and Spondias axillaris) were investigated. The growth of nursery raised seedlings was measured at 3 month intervals until two years old in terms of absolute growth rate (AGR), relative growth rate (RGR), net assimilation rate (NAR), leaf area ratio (LAR), leaf weight ratio (LWR), stem weight ratio (SWR), root weight ratio (RWR) and root-shoot ratio (RSR). Spondias axillaris and Machilus edulis had the maximum AGR, RGR, LAR and SWR among all species. LWR was highest for B. sapida. RGR, LAR and LWR declined with the age of seedlings. RGR was negatively correlated with NAR, SWR, RWR and RSR, though it showed a positive relationship with LAR. For all species, seedlings attained significant sizes after one year of age, and showed reasonable survival after transplantation into the farmers' fields. It is expected that information on the growth behaviour of these species would be useful while they are adopted into agroforestry systems. It is suggested that these species should be multiplied at large scale and distributed to the local inhabitants to reduce pressure on them in natural stands as well as provide economic benefit to the subsistence farmers.

  10. Phytoremediation potential of Phragmites australis in Hokersar wetland - a Ramsar site of Kashmir Himalaya.

    Science.gov (United States)

    Ahmad, Syed Shakeel; Reshi, Zafar A; Shah, Manzoor A; Rashid, Irfan; Ara, Roshan; Andrabi, Syed M A

    2014-01-01

    Heavy metals are an important class of pollutants with both lethal and sublethal effects on organisms. Wetlands are cheap natural alternatives for removal of heavy metals from soils; however, wetland plants vary greatly in their degree of metal uptake. Hokersar wetland, a Ramsar site of Kashmir Himalaya, India is a game reserve of international importance that provides suitable habitat for resident birds and an excellent stopover point for migratory birds visiting from Palaearctic breeding grounds in Central Asia, China, N-Europe and Siberia. The toxicity of chronic dietary metal exposure in birds may have adverse reproductive effects which include decreased egg production, decreased hatchability, and increased hatchling mortality. Thus, the present study aimed to assess the heavy metal sequestration capability of one of the most common wetland plant species Phragmites australis in Hokersar wetland. The accumulation of the different elements was in order of Al > Mn > Ba > Zn > Cu > Pb > Mo > Co > Cr > Cd > Ni. Translocation factor, i.e. ratio of shoot to root metal concentration revealed that metals were largely retained in the roots of P. australis, thus reducing the supply of metals to avifauna and preventing their bio-accumulation. PMID:24933910

  11. Impact of Climate Change on Potential Distribution of Chinese Caterpillar Fungus (Ophiocordyceps sinensis) in Nepal Himalaya

    OpenAIRE

    Shrestha, Uttam Babu; Bawa, Kamaljit S.

    2014-01-01

    Climate change has already impacted ecosystems and species and substantial impacts of climate change in the future are expected. Species distribution modeling is widely used to map the current potential distribution of species as well as to model the impact of future climate change on distribution of species. Mapping current distribution is useful for conservation planning and understanding the change in distribution impacted by climate change is important for mitigation of future biodiversit...

  12. The potential drivers in forming avian biodiversity hotspots in the East Himalaya Mountains of Southwest China.

    Science.gov (United States)

    Lei, Fumin; Qu, Yanhua; Song, Gang; Alström, Per; Fjeldså, Jon

    2015-03-01

    Little has been published to describe or interpret Asian biodiversity hotspots, including those in the East Himalayan Mountains of Southwest China (HMSC), thus making necessary a review of the current knowledge. The Pliocene and Pleistocene geological and glacial histories of the Asian continent differ from those of Europe and North America, suggesting different mechanisms of speciation and extinction, and, thus, different responses to climate changes during the Quaternary glaciations. This short review summarizes potential drivers in shaping and maintaining high species richness and endemism of birds in the HMSC. The geographical location at the junction of different biogeographical realms, the wide range of habitats and climates along the extensive elevational range, the complex topography and the distinct geological history of this region have probably contributed to the evolution of an exceptionally species-rich and endemic-rich, specialized montane avian fauna. The Mountain systems in the HMSC may have provided refugia where species survived during the glacial periods and barriers for preventing species dispersal after the glacial periods. More studies are required to further test this refugia hypothesis by comparing more cold-tolerent and warm-tolerent species. PMID:25316284

  13. Exotic Lolium perenne Varieties: Their Forage Value and Soil Cover Potential in Himalayas Region

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    S. D. Ahmad

    2001-01-01

    Full Text Available Rawalakot lies under humid temperate region at the height of 5500 ft from the sea level. The area is hilly and soils are prone to heavy erosion due to the loss of vegetative cover. Winter frost and snow often kills the local forages and thus depriving the livestock from green herbage altogether. Seven varieties of Lolium perenne (perennial ryegrass from European and American germplasm were evaluated for their forage value and soil cover potential under Rawalakot conditions. All varieties compared were diploid (2n = 14. The comparison was based on plant height, fresh and dry matter yield, number of cuttings/ year and tillers plant-1. The variety VA88002 was found to be the best one in plant height and dry and fresh herbage yield followed by SERVO and APUS. When tiller number was compared, the variety APUS was found to be at the top followed by VA88001 and others. All varieties were of spreading nature with increasing persistence in following years and found to be suitable for cutting, grazing and soil conservation

  14. Detection of snow melt and freezing in Himalaya using OSCAT data

    Indian Academy of Sciences (India)

    Rajashree V Bothale; P V N Rao; C B S Dutt; V K Dadhwal

    2015-02-01

    A study of the snow cover melt and freeze using Ku band Oceansat scatterometer (OSCAT) HH polarised backscatter coefficient (0HH) for 2011 and 2012 is reported for the Himalayas, which contain the world’s largest reserve of ice and snow outside polar regions. The analysis shows spatial and temporal inter-annual variations in the onset of melt/freeze across four regions (Upper Himalaya, Western Himalaya, Central Himalaya, and Eastern Himalaya), nine elevation bands and four aspect zones. A threshold based on temperature–0HH relation and average 0HH for the months January–March was used for melt/freeze detection. When the three consecutive images (6 days) satisfied the threshold, the day of first image was selected as melt onset/freeze day. The average melt onset dates were found to be March 11 ± 11 days for Eastern Himalaya, April 3 ± 18 days for Central Himalaya, April 16 ± 27 days for Western Himalaya, and May 12 ± 18 days for Upper Himalaya. Similarly average freeze onset dates were found to be August 23 ± 27 days for Eastern Himalaya, September 08 ± 24 days for Central Himalaya, August 27 ± 11 days for Western Himalaya, and September 13 ± 11 days for Upper Himalaya. All the zones experienced the melt onset earlier by around 20 days in 2011 at elevation above 5000 m. All the zones experienced freeze earlier in 2012, with onset being 18, 19, 11, and 21 days earlier in Eastern, Central, Western, and Upper Himalaya, respectively.

  15. Ethnobotany in the Nepal Himalaya

    OpenAIRE

    Bussmann Rainer W; Kunwar Ripu M

    2008-01-01

    Abstract Background Indigenous knowledge has become recognized worldwide not only because of its intrinsic value but also because it has a potential instrumental value to science and conservation. In Nepal, the indigenous knowledge of useful and medicinal plants has roots in the remote past. Methods The present study reviews the indigenous knowledge and use of plant resources of the Nepal Himalayas along the altitudinal and longitudinal gradient. A total of 264 studies focusing on ethnobotany...

  16. Evolution of supra-glacial ponds on a debris-covered Chamlang South Glacier, Nepal Himalaya to a potentially dangerous glacial lake

    Science.gov (United States)

    Lamsal, D.; Sawagaki, T.; Watanabe, T.; Sakai, A.

    2013-12-01

    A number of moraine dammed glacial lakes have been developed in the Himalayan region since 1950s as a result of melting and retreat of debris-covered glaciers. Such glacial lakes sometimes produce devastating glacier lake outburst floods (GLOFs) which are often several times bigger than normal climatic floods. In Nepal Himalaya, about a score glacial lakes have been identified as ';potentially dangerous' largely relying on remote sensing image analyses. Chamlang South Glacier Lake in the Eastern Nepal Himalaya, which evolved from few tiny supra-glacial ponds in 1960s on debris-covered Chamlang South Glacier into a large glacial lake is one among them. Moreover, the lake has been repeatedly cited as a potentially dangerous lake for a glacial lake outburst flood (GLOF) and also regarded as one of the most highly prioritized critical lakes in Nepal Himalaya. However, detailed investigation of the lake either by field survey or remote sensing has not been carried out on Chamlang South Glacier/Glacier Lake hitherto. We carried out surface area and bathymetric mappings of the lake, detailed topographic mappings of moraine dam complex and surrounding of the glacial lake, and field assessment to examine the development of Chamlang South Glacier Lake, and to assess its prospect of GLOF and potential volume of water to be released from the lake in the event of dam breach. High-resolution Corona KH-4A and Advanced Land Observing Satellite (ALOS) PRISM stereo-data taken in 1964 and 2006 respectively were processed to generate digital terrain models (DTMs). Surface area of supra-glacial ponds in 1964 was 0.040 km2 which grew to 0.636 km2 by 1992 and reached 0.864 km2 by 2000 and virtually stopped expanding thereafter. Produced bathymetric map revealed the lake to be 87 m deep (maximum) and volume of water contained in the lake was calculated to be ~35.6 × 106 m3. Extensive surface lowering as high as 156.9 m, and average surface lowering by 2.2 m/year is found. All topographic and geomorphic conditions (e.g., position and condition of hanging glacier, precarious mountain slope surrounding the lake conducive to ice/glacier and rock falls, steep, high and fragile terminal moraine topography, high relative height between the lake bottom and stable ground at the foothill of terminal moraines, low-raised dam in dead-ice area adjacent to lake), and existence of seepage in end moraine complex favor the lake to be potentially dangerous. However, the lake has a wide dead-ice area between the lake and end moraine dam that most likely neutralize displacement waves produced in the event of snow/ice avalanche or rock fall into the lake. Nevertheless, there is likely to drain almost all water contained in the lake (~35.6 × 106 m3) if dam breach of Chamlang South Glacier Lake occurs. In a nutshell, prospect of GLOF from the lake is moderate; however, if moraine dam breaks, potential volume of water to be drained would apparently be high.

  17. Natural hazards versus climate change and their potential impacts in the dry, northern Himalayas: focus on the upper Kali Gandaki (Mustang District, Nepal)

    OpenAIRE

    Fort, Monique

    2014-01-01

    In the Himalayas, the consequences of climate change are a fairly debated issue, mainly questioning the availability of water resources to the lowland population. North of the monsoon Himalayas, a semi-arid, continental climate prevails and settlements rely economically mostly on irrigated crops, high altitude rangelands, trade and tourism. The upper Kali Gandaki (Mustang) is situated in this area, with sharp contrasts between valley bottoms (\\3,000 m) and high, glaciated peaks (up to [8,000 ...

  18. Potential theory—selected topics

    CERN Document Server

    Aikawwa, Hiroaki

    1996-01-01

    The first part of these lecture notes is an introduction to potential theory to prepare the reader for later parts, which can be used as the basis for a series of advanced lectures/seminars on potential theory/harmonic analysis. Topics covered in the book include minimal thinness, quasiadditivity of capacity, applications of singular integrals to potential theory, L(p)-capacity theory, fine limits of the Nagel-Stein boundary limit theorem and integrability of superharmonic functions. The notes are written for an audience familiar with the theory of integration, distributions and basic functional analysis.

  19. Export market potential for selected horticultural crops

    International Nuclear Information System (INIS)

    This paper examines the feasibility of utilising an irradiation plant to disinfest fresh fruit and vegetables destined for export markets. It examines the export market potential of selected crops with the prime view of estimating likely trends in export markets in the future. These trends will have a significant bearing on throughput levels, and hence on the economic viability of an ionising energy plant

  20. Electrode potential and selective ionic adsorption

    International Nuclear Information System (INIS)

    A simple description of the electrode potential based on the selective ionic adsorption is proposed. It is shown that if the adsorption-desorption coefficients entering in the Langmuir kinetic equation for the adsorption at the limiting surfaces are not identical, a difference of potential between the electrode and the bulk of the solution exists. In the case where the thickness of the sample is large with respect to the length of Debye, this difference of potential depends only on the adsorption-desorption coefficients and on the length of Debye of the ionic solution.

  1. Electrode potential and selective ionic adsorption

    Energy Technology Data Exchange (ETDEWEB)

    Alexe-Ionescu, A.L. [University Politehnica of Bucharest, Faculty of Applied Sciences, Splaiul Independentei 313, 060042 Bucharest (Romania); Dipartimento di Fisica, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino (Italy); Laboratory for Engineering of the Neuromuscular System, and Dipartimento di Elettronica, Corso Duca degli Abruzzi 24, 10129 Torino (Italy); Barbero, G. [Dipartimento di Fisica, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino (Italy)], E-mail: giovanni.barbero@polito.it; Merletti, R. [Laboratory for Engineering of the Neuromuscular System, and Dipartimento di Elettronica, Corso Duca degli Abruzzi 24, 10129 Torino (Italy)

    2009-04-27

    A simple description of the electrode potential based on the selective ionic adsorption is proposed. It is shown that if the adsorption-desorption coefficients entering in the Langmuir kinetic equation for the adsorption at the limiting surfaces are not identical, a difference of potential between the electrode and the bulk of the solution exists. In the case where the thickness of the sample is large with respect to the length of Debye, this difference of potential depends only on the adsorption-desorption coefficients and on the length of Debye of the ionic solution.

  2. Evolution of the Himalaya

    Science.gov (United States)

    Valdiya, K. S.

    1984-06-01

    The compression and attendant deformation of a thick and vast sedimentary prism formed since Early Riphean times on the northern continental margin of the Indian craton gave rise to the Himalaya mountains as a result of convergence and collision of the Indian and Asian plates. The oceanic trench-sediments, tectonically implanted with sea-floor material and intimately associated with calc-al-kaline volcanics in the narrow Sindhu-Tsangpo belt extending from Kohistan through Dras, Leh, Darchen (Mansarovar) to Shigatse and beyond, represent the subduction-island arc complex which developed south of the dynamic southern margin of the Asian continent and was welded to the colliding Indian plate during the late Eocene to Oligocene period. This complex is fringed to the north by a wide zone of Andean-type granitic bodies. The evolution of the Himalayan orogen is closely connected with the development of the present-day Andaman-Nicobar-Indonesia island arc-subduction system in the southeast and the Makran Ranges-Oman Trench in the southwest. The evolution of the Himalaya was accomplished in four major phases of tectonic upheaval during the late Cretaceous to Palaeocene (Karakoram phase), late Eocene to Oligocene (Malla Johar phase), middle Miocene to Pontian (Sirmurian phase), and late Pliocene to middle Pleistocene (Siwalik phase). While the Karakoram phase marks the convergence of continents and the Malla Johar phase represents the collision and subduction, it was during the Sirmurian upheaval that the main tectonic features developed and the Himalaya acquired its distinctive structural complexion

  3. Glacial lakes in the Indian Himalayas--from an area-wide glacial lake inventory to on-site and modeling based risk assessment of critical glacial lakes.

    Science.gov (United States)

    Worni, Raphael; Huggel, Christian; Stoffel, Markus

    2013-12-01

    Glacial lake hazards and glacial lake distributions are investigated in many glaciated regions of the world, but comparably little attention has been given to these topics in the Indian Himalayas. In this study we present a first area-wide glacial lake inventory, including a qualitative classification at 251 glacial lakes >0.01 km(2). Lakes were detected in the five states spanning the Indian Himalayas, and lake distribution pattern and lake characteristics were found to differ significantly between regions. Three glacial lakes, from different geographic and climatic regions within the Indian Himalayas were then selected for a detailed risk assessment. Lake outburst probability, potential outburst magnitudes and associated damage were evaluated on the basis of high-resolution satellite imagery, field assessments and through the use of a dynamic model. The glacial lakes analyzed in the states of Jammu and Kashmir and Himachal Pradesh were found to present moderate risks to downstream villages, whereas the lake in Sikkim severely threatens downstream locations. At the study site in Sikkim, a dam breach could trigger drainage of ca. 16×10(6)m(3) water and generate maximum lake discharge of nearly 7000 m(3) s(-). The identification of critical glacial lakes in the Indian Himalayas and the detailed risk assessments at three specific sites allow prioritizing further investigations and help in the definition of risk reduction actions. PMID:23218457

  4. Antioxidant, Hepatoprotective Potential and Chemical Profiling of Propolis Ethanolic Extract from Kashmir Himalaya Region Using UHPLC-DAD-QToF-MS

    Science.gov (United States)

    Wali, Adil F.; Avula, Bharathi; Ali, Zulfiqar; Khan, Ikhlas A.; Mushtaq, Ahlam; Rehman, Muneeb U.; Akbar, Seema; Masoodi, Mubashir Hussain

    2015-01-01

    The aim of this study was to examine hepatoprotective effect of ethanolic extract of propolis (KPEt) from Kashmir Himalaya against isoniazid and rifampicin (INH-RIF) induced liver damage in rats. Hepatic cellular injury was initiated by administration of INH-RIF combination (100?mg/kg) intraperitoneal (i.p.) injection for 14 days. We report the protective effects of KPEt against INH-RIF induced liver oxidative stress, inflammation, and enzymatic and nonenzymatic antioxidants. Oral administration of KPEt at both doses (200 and 400?mg/kg body weight) distinctly restricted all modulating oxidative liver injury markers and resulted in the attenuation of INH-RIF arbitrated damage. The free radical scavenging activity of KPEt was evaluated by DPPH, nitric oxide, and superoxide radical scavenging assay. The components present in KPEt identified by ultra high performance liquid chromatography diode array detector time of flight-mass spectroscopy (UHPLC-DAD-QToF-MS) were found to be flavonoids and phenolic acids. The protective efficacy of KPEt is possibly because of free radical scavenging and antioxidant property resulting from the presence of flavonoids and phenolic acids. PMID:26539487

  5. Methanogens at the top of the world: occurrence and potential activity of methanogens in newly deglaciated soils in high-altitude cold deserts in the Western Himalayas

    Directory of Open Access Journals (Sweden)

    RoeyAngel

    2013-12-01

    Full Text Available Methanogens typically occur in reduced anoxic environments. However, in recent studies it has been shown that many aerated upland soils, including desert soils also host active methanogens. Here we show that soil samples from high–altitude cold deserts in the western Himalayas (Ladakh, India produce CH4 after incubation as slurry under anoxic conditions at rates comparable to those of hot desert soils. Samples of matured soil from three different vegetation belts (arid, steppe, and subnival were compared with younger soils originating from frontal and lateral moraines of receding glaciers. While methanogenic rates were higher in the samples from matured soils, CH4 was also produced in the samples from the recently deglaciated moraines. In both young and matured soils, those covered by a biological soil crust (biocrust were more active than their bare counterparts. Isotopic analysis showed that in both cases CH4 was initially produced from H2/CO2 but later mostly from acetate. Analysis of the archaeal community in the in situ soil samples revealed a clear dominance of sequences related to Thaumarchaeota, while the methanogenic community comprised only a minor fraction of the archaeal community. Similar to other aerated soils, the methanogenic community was comprised almost solely of the genera Methanosarcina and Methanocella, and possibly also Methanobacterium in some cases. Nevertheless, approximately 103 gdw-1 soil methanogens were already present in the young moraine soil together with cyanobacteria. Our results demonstrate that Methanosarcina and Methanocella not only tolerate atmospheric oxygen but are also able to survive in these harsh cold environments. Their occurrence in newly deglaciated soils shows that they are early colonisers of desert soils, similar to cyanobacteria, and may play a role in the development of desert biocrusts.

  6. The role of glaciers in stream flow from the Nepal Himalaya

    OpenAIRE

    Alford, D; Armstrong, R.

    2010-01-01

    Recent concerns related to the potential impacts of the retreat of Himalayan glaciers on the hydrology of rivers originating in the catchment basins of the Himalaya have been accompanied by few analyses describing the role of glaciers in the hydrologic regime of these mountains. This is, at least in part, a result of the relative inaccessibility of the glaciers of the Himalaya, at altitudes generally between 4000–7000 m, and the extreme logistical difficulties of: 1) reaching the glaciers, an...

  7. Anticancer potential of selected Fallopia Adans species

    Science.gov (United States)

    OLARU, OCTAVIAN TUDOREL; VENABLES, LUANNE; VAN DE VENTER, MARYNA; NITULESCU, GEORGE MIHAI; MARGINA, DENISA; SPANDIDOS, DEMETRIOS A.; TSATSAKIS, ARISTIDIS M.

    2015-01-01

    The aim of the present study was to determine the anticancer potential of three species belonging to the Fallopia genus (Polygonaceae): Fallopia convolvulus (F. convolvulus, Fallopia dumetorum (F. dumetorum) and Fallopia aubertii (F. aubertii). For this purpose, crude extracts were obtained and characterized for their phenolic and flavonoid total content and examined for their anticancer activity on three tumor cell lines: breast cancer (MCF7), colon carcinoma (Caco-2) and cervical cancer (HeLa) cells. The cytotoxic potential of the three species was assessed by MTT assay, cell cycle analysis and by the evaluation of mitochondrial membrane potential (MMP). The acute toxicity of the extracts was evaluated using one in vitro cell model (Vero cells, an African Green monkey kidney cell line) and two invertebrate in vivo models (Daphnia magna and Artemia salina). The highest total phenolic and flavonoid content was found in the F. aubertii flower extracts. The cytotoxic effects of the extracts from F. aubertii and F. convolvulus on all three cell lines were examined at concentrations ranging from 3 to 300 µg/ml. G2/M cell cycle arrest was induced by all the extracts, and a significant increase in the subG1 cell population was observed. The hydroethanolic extract from the flowers of F. aubertii induced cell apoptosis more rapidly than the other extracts. The MMP indicates the involvement of the mitochondria in the induction of apoptosis. A positive correlation between the total phenolic content of the extracts and the IC50 values against the HeLa cells was also noted. None of the extracts exhibited significantly toxic effects. Considering the antitumor potential of F. aubertii and F. convolvulus, these two species may represent a good source of plant extracts with anticancer properties. PMID:26622671

  8. Prospects of Sustainable Livestock Farming in the Uttarakhand Himalaya, India

    OpenAIRE

    V. P. Sati; Singh, R.B.

    2010-01-01

    Livestock farming forms an integral part in the economy of the Uttarakhand Himalaya and plays an important role in the mixed crop farming system. In addition, high diversity in livestock composition is the characteristic features of the mainland of Uttarakhand. The state obtains high potential of milk production because of availability of fodder as a form of extensive grasslands, which are locally known as bugyals or kharaks and fodder trees. Livestock, other than milk production, are widely ...

  9. Lg attenuation tomographic models of Himalaya and southern Tibet

    Science.gov (United States)

    Singh, Chandrani; Mondal, Pushkar; Singh, Sagar; Mohanty, Debasis D.; Jaiswal, Namrata; Ravi Kumar, M.

    2015-11-01

    We investigate the Lg attenuation structure of the crust beneath the tectonically complex Himalaya and southern Tibet regions adopting a tomographic regionalization method. A total of 1671 earthquake waveforms registered at 38 seismic stations operated in the region are selected for the initial LgQ measurements using the standard two-station method. Q0 (1 Hz LgQ) values of 76 high quality interstation paths are finally considered as input for the tomographic inversion. The estimates of Q0 exhibit distinct variations in the crustal attenuation from north to south across the whole region. The zones of lowest Q0 values (attenuation and velocity structure reported for the region. We interpret the variations in the attenuation characteristics in terms of both the intrinsic and scattering contributions caused by thermal effects, presence of aqueous fluids as well as heterogeneities present below these seismically active regions. Our results are found to be comparable with the other parts of Himalaya and Tibet.

  10. Lithospheric Structure and Earthquakes beneath Kashmir Himalaya

    Science.gov (United States)

    Wanchoo, S. K.; Powali, D.; Sharma, S.; Mitra, S.; Priestley, K. F.; Gaur, V. K.

    2014-12-01

    Over the last two centuries, convergence between India and Tibet has outpaced the cumulative slip released through Himalayan earthquakes and have resulted in seismic gap across Kashmir Himalaya. Recent GPS geodetic data from Kashmir show that the ongoing convergence is accumulated as elastic strain within a ~200 km wide locked decollement and is sufficiently stressed to drive a magnitude 8 or greater event. Recently published focal mechanism of the mb 5.7 (2013) Kishtwar earthquake and hypocentral distribution of small-to-moderate seismicity for the past 60 years, showed that the down dip end of the locked decollement is currently active and could possibly be the site of initiation of a future great earthquake. In order to assess the seismic hazard in this Kashmir gap, we require a detailed knowledge of the lithospheric structure and use it to reliably locate active faults. A pilot seismological experiment, of nine broadband seismographs, have been deployed across the Kashmir Himalaya to achieve this goal. These stations are sited on the Siwalik Himalaya (AKNR, NGRT, SMVD, SUND and TAPN), the Lesser Himalaya (RAMN and UDHM) and the Higher Himalaya (BADR and PHAG), and straddle major Himalayan thrust zones. Most of these stations have recorded high quality broadband data for a year, which has been used to compute receiver functions and relocate local earthquakes. The Moho Ps is the strongest arrival on all the receiver functions, and highlights the base of the underthrusting Indian crust as a large impedance contrast boundary. Forward modeling of receiver functions show that the crustal thickness increases from ~40 km beneath the Siwalik Himalaya to ~48 km beneath the Lesser Himalaya and to ~52 km beneath the Higher Himalaya. The average crustal Vp/Vs points to a felsic Indian crust underthrusting the Kashmir Himalaya. Relocated local earthquakes cluster around the hypocenter of the Kishtwar earthquake and attests to the active downdip end of the locked decollement.

  11. Spatio-Temporal Patterns of Surface Irradiance in the Himalaya

    Science.gov (United States)

    Dobreva, I. D.; Bishop, M. P.

    2014-12-01

    Climate-glacier dynamics in the Himalaya are complex. Research indicates extreme local variability in glacier fluctuations and the presence of regional trends. The glaciers in the Karakoram Himalaya depart from world trends of glacier recession, as many are advancing or surging. Nevertheless, glacier sensitivity to climate change has yet to be quantitatively assessed given numerous controlling factors. We attempt to address part of the problem by evaluating the role of topography in explaining variations in surface irradiance. Specifically, we developed a spectral-based topographic solar radiation model that accounts for multi-scale topographic effects. We evaluate surface irradiance simulations over a multitude of glaciers across the Karakoram and Nepalese Himalaya and examine spatio-temporal patterns to determine which alpine glaciers are more susceptible to radiation forcing. Simulation results reveal that many Nepalese glaciers characterized by rapid downwasting, retreat and expanding proglacial lakes, exhibit relatively high-magnitude daily irradiance patterns spatially focused over the terminus region, while other glacier surface areas received less short-wave irradiance. These results were found to be associated with basin-scale relief conditions and topographic shielding. Altitudinal variation in glacier surface irradiance was found to increase during the later portion of the ablation season, as changes in solar geometry produce more cast shadows that protect glaciers given extreme relief. Topographic effects on surface irradiance vary significantly from glacier to glacier, demonstrating the important role of glacier and mountain geodynamics on glacier sensitivity to climate change. Spatial and altitudinal patterns, coupled with information regarding supraglacial debris distribution, depth and ice-flow velocities, may potentially explain glacier sensitivity to climate change and the local variability of glacier fluctuations in the Himalaya.

  12. Selective suppression of Eigen states with an absorptive delta potential

    International Nuclear Information System (INIS)

    Delta function potentials are used to explain short range elastic impurities and nature of the spectrum generated by the delta function potential embedded in a box and to construct model atomic systems interacting with the electromagnetic fields leading to multi photon absorption and ionization process. Similar study can be carried out in a nuclear system to analyze different properties of radioactive ions. The resonances generated when particle traverses across two delta potentials in one-dimension (ID) are studied. In this contribution, a novel feature is demonstrated that an absorptive delta potential suitably placed within a potential pocket can be used to selectively manipulate and suppress the resonances generated by the pocket

  13. Wind energy potential in selected areas in Jordan

    International Nuclear Information System (INIS)

    Highlights: ? This paper investigates the potential of producing wind power. ? Four locations are selected for wind power generation. ? The payback period is calculated and found reasonable. ? This study reveals that the total rated wind power that can be generated from the four selected wind farms is 136 MW. ? On the other hand, the expected total energy that can be produced from the four selected wind farms is 18.9 × 103 GW h. - Abstract: The present paper investigates the potential of wind energy in selected areas in Jordan. The aim of this work is to set up promising wind farms that are able to feed electricity to the Jordanian distribution authority with excellent percentage of clean energy. There are some particular locations in Jordan where the wind potential is very promising for economical electrical power generation. Four of these promising locations are investigated in this paper for the possibility of building and investing 100 MW wind turbine in each of these four locations. The environmental data needed to perform the present study are obtained from the local Meteorological department. The suggested wind turbines to be implemented in each of the four locations are selected from the international rating and specification catalogues of wind turbine manufacturers. This study reveals that the total rated wind power that can be generated from the four selected wind farms is 136 MW. On the other hand, the expected total energy that can be produced from the four selected wind farms is 18.9 × 103 GW h.

  14. Changes in Rongbuk lake and Imja lake in the Everest region of Himalaya

    Science.gov (United States)

    Chen, W.; Doko, T.; Liu, C.; Ichinose, T.; Fukui, H.; Feng, Q.; Gou, P.

    2014-12-01

    The Himalaya holds the world record in terms of range and elevation. It is one of the most extensively glacierized regions in the world except the Polar Regions. The Himalaya is a region sensitive to climate change. Changes in the glacial regime are indicators of global climate changes. Since the second half of the last century, most Himalayan glaciers have melted due to climate change. These changes directly affected the changes of glacial lakes in the Himalayan region due to the glacier retreat. New glacial lakes are formed, and a number of them have expanded in the Everest region of the Himalayas. This paper focuses on the two glacial lakes which are Imja Lake, located at the southern slope, and Rongbuk Lake, located at the northern slope in the Mt. Everest region, Himalaya to present the spatio-temporal changes from 1976 to 2008. Topographical conditions between two lakes were different (Kruskal-Wallis test, p Lake was located at 623 m higher than Imja Lake, and radiation of Rongbuk Lake was higher than the Imja Lake. Although size of Imja Lake was larger than the Rongbuk Lake in 2008, the growth speed of Rongbuk Lake was accelerating since 2000 and exceeds Imja Lake in 2000-2008. This trend of expansion of Rongbuk Lake is anticipated to be continued in the 21st century. Rongbuk Lake would be the biggest potential risk of glacial lake outburst flood (GLOF) at the Everest region of Himalaya in the future.

  15. Physiological and biochemical plasticity of Lepidium latifolium as 'sleeper weed' in Western Himalayas.

    Science.gov (United States)

    Bhat, Hilal A; Kaur, Tarandeep; Bhat, Rohini; Vyas, Dhiraj

    2016-03-01

    To understand the spread of native populations of Lepidium latifolium growing in different altitudes in Ladakh region of Western Himalayas, photosynthetic and fluorescence characteristics were evaluated in relation to their micro-environment. Three sites representing sparsely populated (SPS), moderately populated (MPS) and densely populated site (DPS) were selected. Results showed that the DPS had higher photosynthetic accumulation than MPS and SPS. The higher transpiration rate at DPS despite lower vapor pressure deficit and higher relative humidity suggest the regulation of its leaf temperature by evaporative cooling. Intrinsic soil parameters such as water holding capacity and nutrient availability also play crucial role in higher biomass here. The quantum efficiency of PSII photochemistry (Fv /Fm , non-photochemical quenching (NPQ), ΦPSII ) and light curve at various PPFDs suggests better light harvesting potential and light compensation point at DPS than the other two sites. Concomitantly, plants at SPS had significantly higher lipid peroxidation, suggesting a stressful environment, and higher induction of antioxidative enzymes. Metabolic content of reduced glutathione also suggests an efficient mechanism in DPS and MPS than SPS. High light intensities at MPS are managed by specialized contrive of carotenoid pigments and PsbS gene product. Large pool of violaxanthin and lutein plays an important role in this response. It is suggested that L. latifolium is present as 'sleeper weed' that has inherent biochemical plasticity involving multiple processes in Western Himalayas. Its potential spread is linked to site-specific micro-environment, whereby, it prefers flat valley bottoms with alluvial fills having high water availability, and has little or no altitudinal effect. PMID:26260637

  16. Determination of Half-wave Potentials of Selected Chlorophenols

    Scientific Electronic Library Online (English)

    M.O., Iwunze; B., Abel.

    2012-09-01

    Full Text Available Cyclic voltammetry was used in cetyltrimethylammonium bromide (CTAB) micellar solution to determine the half-wave potentials of selected chlorophenols, CPs. It is observed that all the electrochemical parameters of the studied CPs decrease with an increase in the number of chlorine atom(s) attached [...] to the parent compound. The mathematical relationship between the obtained E1/2 and the number of chlorine atoms in the parent compound is given. The formal potentials, E0', of the CPs are approximated from the obtained half-wave potentials.

  17. Microwave-dressed state-selective potentials for atom interferometry

    CERN Document Server

    Guarrera, V; Reichel, J; Rosenbusch, P

    2015-01-01

    We propose a novel and robust technique to realize a beam splitter for trapped Bose-Einstein condensates (BECs). The scheme relies on the possibility of producing different potentials simultaneously for two internal atomic states. The atoms are coherently transferred, via a Rabi coupling between the two long-lived internal states, from a single well potential to a double-well. We present numerical simulations supporting our proposal and confirming excellent efficiency and fidelity of the transfer process with realistic numbers for a BEC of $^{87}$Rb. We discuss the experimental implementation by suggesting state-selective microwave potentials as an ideal tool to be exploited for magnetically trapped atoms. The working principles of this technique are tested on our atom chip device which features an integrated coplanar micro-wave guide. In particular, the first realization of a double-well potential by using a microwave dressing field is reported. Experimental results are presented together with numerical simu...

  18. The duct selective volumetric receiver: potential for different selectivity strategies and stability issues

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Casals, X. [Universidad Pontificia Comillas-ICAI, Madrid (Spain). Dept. de Fluidos y Calor; Ajona, J.I. [Departamento de Energia Solar, Viessemann, Poligono Industrial San Marcos, Getafe (Spain)

    1999-07-01

    Recently much theoretical and experimental work has been conducted on volumetric receivers. However, not much attention has been paid to the possibilities of using different selectivity mechanisms to minimize radiation thermal losses, which are the main ones at high operating temperature. In this paper we present a duct volumetric receiver model and its results, which allow the evaluation of different selectivity strategies such as: conventional {epsilon}/{alpha}, geometry, frontal absorption and diffuse/specular reflection. We propose a new concept of selective volumetric receivers based on a solar-specular/infrared-diffuse radiative behaviour and evaluate its potential for efficiency improvement. In recent work on volumetric receivers based on simplified models, it has been concluded that the duct volumetric receiver is inherently unstable when working with high solar flux. We didn't find any unstable receiver behaviour even at very high solar fluxes, and conclude that a substantial potential for efficiency improvement exists if selectivity mechanisms are properly combined. (author)

  19. Measuring Mitochondrial Membrane Potential with a Tetraphenylphosphonium-Selective Electrode.

    Science.gov (United States)

    Moreno, António J; Santos, Dario L; Magalhães-Novais, Sílvia; Oliveira, Paulo J

    2015-01-01

    Mitochondrial bioenergetics is based on the generation of the protonmotive force by the electron transport chain. The protonmotive force is used by mitochondria for different critical aspects of its normal function, ranging from calcium accumulation to the synthesis of ATP. The transmembrane electric potential (??) is the major component of the protonmotive force and is also the main responsible for ATP synthesis by mitochondrial ATP synthase. Although several methods can be used to measure the ??, the use of the tetraphenylphosphonium cation (TPP(+) )-selective electrode is still a method of election due to its sensitivity. The method is based on the accumulation of TPP(+) by energized mitochondria, which develop a negative charge in the matrix due to the ejection of protons. This unit describes how to build a custom-made TPP(+) -selective electrode and how to establish the necessary set-up to follow ?? fluctuations in isolated mitochondrial fractions. © 2015 by John Wiley & Sons, Inc. PMID:26250398

  20. Ectomycorrhizal Diversity Associated with Cedrus deodara and Pinus wallichiana in the Kashmir Himalaya, India

    OpenAIRE

    Zahoor Ahmad Itoo; ZAFAR A. RESHI

    2014-01-01

    The present study was undertaken to document the ectomycorrhizal diversity associated with the Cedrus deodara and Pinus wallichiana in the Kashmir Himalaya, India. The extensive field surveys carried out in the Kashmir Himalaya at five study sites resulted in the collection and identification of 76 potential ectomycorrhizal fungal species associated with the Cedrus deodara and Pinus wallichiana. Maximum 32 number of species were found associated with Pinus wallichiana, 19 with Cedrus deodara ...

  1. The role of glaciers in stream flow from the Nepal Himalaya

    Directory of Open Access Journals (Sweden)

    D. Alford

    2010-04-01

    Full Text Available Recent concerns related to the potential impacts of the retreat of Himalayan glaciers on the hydrology of rivers originating in the catchment basins of the Himalaya have been accompanied by few analyses describing the role of glaciers in the hydrologic regime of these mountains. This is, at least in part, a result of the relative inaccessibility of the glaciers of the Himalaya, at altitudes generally between 4000–7000 m, and the extreme logistical difficulties of: 1 reaching the glaciers, and 2 conducting meaningful research once they have been reached. It is apparent that an alternative to traditional "Alpine" glaciology is required in the mountains of the Hindu Kush-Himalaya region. The objectives of the study discussed here have been to develop methodologies that will begin to quantify the role of complete glacier systems in the hydrologic regime of the Nepal Himalaya, and to develop estimates of the potential impact of a continued retreat of these glacier, based on the use of disaggregated low-altitude data bases, topography derived from satellite imagery, and simple process models of water and energy exchange in mountain regions.

    While the extent of mesoscale variability has not been established by studies to date, it is clear that the dominant control on the hydrologic regime of the tributaries to the Ganges Basin from the eastern Himalaya is the interaction between the summer monsoon and the 8000 m of topographic relief represented by the Himalayan wall. All the available evidence indicates that the gradient of specific runoff with altitude resulting from this interaction is moderately to strongly curvilinear, with maximum runoff occurring at mid-altitudes, and minima at the altitudinal extremes. At the upper minimum of this gradient, Himalayan glaciers exist in what has been characterized as an "arctic desert".

    The methodologies developed for this study involve the relationship between area-altitude distributions of catchment basins and glaciers, based on Shuttle Radar Topography Mission (SRTM3 data and water and energy exchange gradients. Based on these methodologies, it is estimated that the contribution of glacier annual melt water to annual stream flow into the Ganges Basin from the glacierized catchments of the Nepal Himalaya represents approximately 4% of the total annual stream flow volume of the rivers of Nepal, and thus, is a minor component of the annual flow of the Ganges River. The models developed for this study indicate that neither stream flow timing nor volume of the rivers flowing into the Ganges Basin from Nepal will be affected materially by a continued retreat of the glaciers of the Nepal Himalaya.

  2. Microwave-dressed state-selective potentials for atom interferometry

    Science.gov (United States)

    Guarrera, V.; Szmuk, R.; Reichel, J.; Rosenbusch, P.

    2015-08-01

    We propose a novel and robust technique to realize a beam splitter for trapped Bose-Einstein condensates (BECs). The scheme relies on the possibility of producing different potentials simultaneously for two internal atomic states. The atoms are coherently transferred, via a Rabi coupling between the two long-lived internal states, from a single well potential to a double-well. We present numerical simulations supporting our proposal and confirming excellent efficiency and fidelity of the transfer process with realistic numbers for a BEC of 87Rb. We discuss the experimental implementation by suggesting state-selective microwave (MW) potentials as an ideal tool to be exploited for magnetically trapped atoms. The working principles of this technique are tested on our atom chip device which features an integrated coplanar MW guide. In particular, the first realization of a double-well potential by using a MW dressing field is reported. Experimental results are presented together with numerical simulations, showing good agreement. Simultaneous and independent control on the external potentials is also demonstrated in the two Rubidium clock states. The transfer between the two states, featuring respectively a single and a double-well, is characterized and it is used to measure the energy spectrum of the atoms in the double-well. Our results show that the spatial overlap between the two states is crucial to ensure the functioning of the beamsplitter. Even though this condition could not be achieved in our current setup, the proposed technique can be realized with current state-of-the-art devices being particularly well suited for atom chip experiments. We anticipate applications in quantum enhanced interferometry.

  3. Global warming may lead to catastrophic floods in the Himalayas; Flomkatastrofe truer Himalaya

    Energy Technology Data Exchange (ETDEWEB)

    Tveitdal, Svein; Bjoerke, Aake

    2002-07-01

    In Nepal, data from 49 surveillance stations show that there has been a distinct temperature increase since the middle of the 1970s, the greatest changes being on the highest summits. When lakes overfill and beaches threaten to break down, this is a result of the global warming that melts the glaciers. The glaciers in Bhutan are observed to decrease by 30 - 40 metres per year, in some years as much as 100 metres. In the village of Tribeni an advanced warning system has been established to warn the 10 000 inhabitants of a potential flood from Lake Tsho Rolpa 108 km upstream. Research from the Himalayas also point to another serious threat. The melting threatens not only human lives, tourism, foot paths, roads, bridges and power stations. Since the mountains are the water towers of the world, filling rivers and lakes with water upon which all life depends, continued shrinking of the world's glaciers as is now observed will cause many rivers and fresh-water systems to dry out. Researchers from the UN Unep programme and International Centre for Integrated Mountain Development have registered at least 44 glacier lakes that are increasing so fast that they may cause outburst floods within five years. Similar investigations are being planned in India, Pakistan and China.

  4. Evolution of earthquake-triggered landslides in the Kashmir Himalaya, northern Pakistan

    Science.gov (United States)

    Khattak, G.A.; Owen, L.A.; Kamp, U.; Harp, E.L.

    2010-01-01

    The influence of the 08 October 2005 Kashmir earthquake and subsequent snow melt and monsoon rainfall on slope stability was evaluated using repeat photography in the Kashmir Himalaya of northern Pakistan. Sixty-eight landslide-affected locations were selected and photographed in November 2005, May/June 2006, June 2007, and August 2007 to evaluate all potential geomorphic changes. Eighty percent of the locations showed no or very little change, 11% of the locations showed a partial vegetation recovery on the slopes, while 9% showed an increase in the landslide area. All those locations that showed an increase in landsliding were located along rivers and/or roads. The small change in landslide extent is remarkable given that the region experienced one of the heaviest monsoon seasons in the last decade and is counter to earlier predictions of accelerated slope erosion by landsliding in the immediate years following the earthquake. Extensive fissures and ground cracks at many localities, however, still present a potential of future landsliding under wetter conditions. ?? 2009 Elsevier B.V. All rights reserved.

  5. CODA Q estimates for Kumaun Himalaya

    Indian Academy of Sciences (India)

    A Paul; S C Gupta; Charu C Pant

    2003-12-01

    Coda (c) estimates for the Kumaun Himalaya region have been obtained in high frequency range. Local earthquakes, recorded by a digital seismic network in the region, which fall in the epicentral distances range of 10 to 80km and with a local magnitude range of 1.4 to 2.8, have been used. The coda waves of 30 sec window length, filtered at seven frequency bands centered at 1.5, 3, 6, 9, 12, 18 and 24 Hz, have been analysed using the single backscattering model. The values of c estimates vary from 65 to 283 at 1.5 Hz to 2119 to 3279 at 24.0 Hz which showed that c is frequency dependent and its value increases as frequency increases. A frequency-dependent c relationship, c = (92 ± 4.73) (1.07 ± .023), is obtained for the region representing the average attenuation characteristics of seismic waves for Kumaun Himalaya region.

  6. Uranium and radon surveys in Siwalik Himalaya

    International Nuclear Information System (INIS)

    Integrated measurements of radon in subsurface soil and groundwater are being used for uranium exploration and earthquake prediction. It is well established that large scale mobilization of uranium and radium is carried out by Himalayan rivers which are major sources of radioactivity on the Indian ocean. Our laboratory has been engaged in uranium/thorium estimation and radon studies in the Siwalik Himalaya since 1980, using scintillometry, track-etch technique, surface barrier silicon-junction detectors and pulse ionisation counters (alpha-loggers). Fission track technique and alpha autoradiography is also used to reveal uranium anomalies in geological samples of the area. Siwalik vertebrate fossil bones from Saharanpur (U.P.), Naraiangarh (Haryana) and Nalagarh (H.P.) show anomalously high uranium content variation from 93.8 to 418 ppm which is a riddle for geochemists. The daily and long term variation of radon was monitored in Siwalik Himalaya since 1989 under a Department of Science and Technology (DST) sponsored project. The effect of meteorological parameters on radon emanation is also studied. Radon results are correlated by the gamma activity and in situ uranium content in the soil of the area. The maximum values of radon are recorded in Chhinjra, Rameda, Kasol and Samurkalan areas of Himachal Pradesh. Results indicate that there is a need to undertake epidemiological study correlating cancer risk with high radon values in the Siwalik Himalaya. (author)

  7. Accelerator mass spectrometry (AMS)-geological perspective and a case study from Ladakh Himalaya

    International Nuclear Information System (INIS)

    Accelerator Mass Spectrometry (AMS) is a recent addition to the conventional mass spectrometry and is based on measurement of cosmogenic radionuclides. It is a highly potential technique to understand a variety of geological problems particularly in geomorphology, paleoclimatology and ocean research and is in fact the only technique to precisely measure erosion rates, river incision rates, sedimentation rates and surface exposure ages. The paper briefly presents the geological perspectives of the AMS technique and some preliminary results from Ladakh Himalaya

  8. Arc parallel extension in Higher and Lesser Himalayas, evidence from western Arunachal Himalaya, India

    Indian Academy of Sciences (India)

    Sharmistha De Sarkar; George Mathew; Kanchan Pande

    2013-06-01

    The existence of E–W extensional features from northeast (NE) Himalaya is poorly documented. Our investigation in the western part of Arunachal Himalaya provides evidences of active Quaternary E–W arc-parallel extensional features in the Higher and Lesser Himalayas. They are represented by arcperpendicular normal faults and arc-parallel sinistral strike-slip faults. We discuss the occurrences of these arc-parallel extensional features in terms of oblique convergence and radial expansion models. The partitioning of stress due to oblique convergence is argued based on evidences of left-lateral slip in NEHimalaya, right-lateral slip in NW-Himalaya and absence of translation in the central part. The amount of arc-parallel extension in the hinterland regions is correlated to the amount of radial shortening in the foreland. The computation of arc-parallel extension in the NE Himalayan arc is carried out by defining a small-circle centered at 88° 39? \\pm 0.7?E longitude and 33° 40? \\pm 0.6?N latitude having a radius of 770.7 ± 15.1 km, for the segment between 92° 01? and 95° 16?E longitudes. The amount of arc-parallel extension estimated is ?110 km for the NE Himalayan segment. Our result agrees closely with the 104 km extension determined based on geodetically computed extension rate and age of initiation of rifting in southern Tibet.

  9. Study on the Swelling Potential of some Selected Rocks

    OpenAIRE

    Pettersen Skippervik, Catrine

    2014-01-01

    Weaknesses zones consisting of sheared and fractured rock mass have a swelling potential in the presence of clays rich in montmorillonite. When it comes to intact rocks there are questions regarding both the swelling potential and the main reasons for swelling in the different rock types. This is experienced in several projects, where swelling of intact rock has been different than what was expected. To better understand what is causing the behaviour of intact rock when exposed to water a com...

  10. Nature and timing of large landslides in the Himalaya and Transhimalaya of northern India

    Science.gov (United States)

    Dortch, Jason M.; Owen, Lewis A.; Haneberg, William C.; Caffee, Marc W.; Dietsch, Craig; Kamp, Ulrich

    2009-06-01

    Four large landslides, each with a debris volume >10 6 m 3, in the Himalaya and Transhimalaya of northern India were examined, mapped, and dated using 10Be terrestrial cosmogenic radionuclide surface exposure dating. The landslides date to 7.7±1.0 ka (Darcha), 7.9±0.8 ka (Patseo), 6.6±0.4 ka (Kelang Serai), and 8.5±0.5 ka (Chilam). Comparison of slip surface dips and physically reasonable angles of internal friction suggests that the landslides may have been triggered by increased pore water pressure, seismic shaking, or a combination of these two processes. However, the steepness of discontinuities in the Darcha rock-slope, suggests that it was more likely to have started as a consequence of gravitationally-induced buckling of planar slabs. Deglaciation of the region occurred more than 2000 years before the Darcha, Patseo, and Kelang Serai landslides; it is unlikely that glacial debuttressing was responsible for triggering the landslides. The four landslides, their causes, potential triggers and mechanisms, and their ages are compared to 12 previously dated large landslides in the region. Fourteen of the 16 dated landslides occurred during periods of intensified monsoons. Seismic shaking, however, cannot be ruled out as a mechanism for landslide initiation, because the Himalaya has experienced great earthquakes on centennial to millennial timescales. The average Holocene landscape lowering due to large landslides for the Lahul region, which contains the Darcha, Patseo, and Kelang Serai landslides, is ˜0.12 mm/yr. Previously published large-landslide landscape-lowering rates for the Himalaya differ significantly. Furthermore, regional glacial and fluvial denudation rates for the Himalaya are more than an order of magnitude greater. This difference highlights the lack of large-landslide data, lack of chronology, problems associated with single catchment/large landslide-based calculations, and the need for regional landscape-lowering determinations over a standardized time period.

  11. Black carbon aerosols over the Himalayas: direct and surface albedo forcing

    Directory of Open Access Journals (Sweden)

    Vijayakumar S. Nair

    2013-09-01

    Full Text Available Absorbing aerosols such as black carbon (BC or dust over high-altitude Himalayan regions have potential implications on the regional climate and hydrological cycle over South Asia. Making use of extensive measurements of atmospheric BC from several Himalayan stations, an assessment of radiative forcing due to direct and snow-albedo darkening is examined. Generally, BC concentration in the atmosphere peaks during pre-monsoon season over the Himalayas and the climatological mean of atmospheric BC over Hanle (western Himalayas, 4.5?km msl and Nepal Climate Observatory-Pyramid (central Himalayas, 5?km msl are 106±27?ng m?3 and 190±95?ng m?3, respectively. Based on the optical and physical properties of composite aerosols measured at Hanle, clear sky direct radiative forcing (DRF at the top of the atmosphere is estimated as 1.69?W m?2 over snow surface and ?1.54?W m?2 over sandy surface during pre-monsoon season. The estimated amount of BC in the snow varied from 117 to 1.7?µg kg?1 for wide range of dry deposition velocities (0.01–0.054?cm s?1 of BC, snow depth (2–10?cm and snow densities (195–512?kg m?3. Using a size-resolved wet scavenging parametrisation, the amount of BC on snow due to wet scavenging is estimated as 29?µg kg?1 for an accumulated snow depth of 27?cm. For the range of 10–200?µg kg?1 of BC in snow, the diurnally averaged forcing due to snow darkening has been found to vary from 0.87 to 10.2?W m?2 for fresh snow and from 2.6 to 28.1?W m?2 for the aged snow, which is significantly higher than the DRF. The direct and surface albedo radiative forcing could lead to significant warming over the Himalayas during pre-monsoon.

  12. Southwest-facing slopes control the formation of debris-covered glaciers in the Bhutan Himalaya

    Directory of Open Access Journals (Sweden)

    H. Nagai

    2013-04-01

    Full Text Available To understand the formation conditions of debris-covered glaciers, we examined the dimension and shape of debris-covered areas and potential debris-supply (PDS slopes of 208 glaciers in the Bhutan Himalaya. This was undertaken using satellite images with 2.5 m spatial resolution for manual delineation of debris-covered areas and PDS slopes. The most significant correlation exists between surface area of southwest-facing PDS slopes and debris-covered area. This result suggests that the southwest-facing PDS slopes supply the largest quantity of debris mantle. The shape of debris-covered areas is also an important variable quantitatively defined using a geometric index. Elongate or stripe-like debris-covered areas on north-flowing glaciers are common throughout the Bhutan Himalaya, associated with the small quantities of debris from north-facing PDS slopes. In contrast, south-flowing glaciers have large ablation zones, entirely covered by debris. Our findings suggest that this difference is caused by effective diurnal freeze–thaw cycles rather than seasonal freeze–thaw cycles, permafrost degradation, or snow avalanches. In terms of geographic setting, local topography also contributes to glacier debris supply and the proportion of debris cover on the studied glaciers is suppressed by the arid Tibetan climate, whereas the north-to-south asymmetric topography of the Bhutan Himalaya has less influence on the proportion of debris cover.

  13. Tree ring imprints of long-term changes in climate in western Himalaya, Indi

    Indian Academy of Sciences (India)

    R R Yadav

    2009-11-01

    Tree-ring analyses from semi-arid to arid regions in western Himalaya show immense potential for developing millennia long climate records. Millennium and longer ring-width chronologies of Himalayan pencil juniper (Juniperus polycarpos), Himalayan pencil cedar (Cedrus deodara) and Chilgoza pine (Pinus gerardiana) have been developed from different sites in western Himalaya. Studies conducted so far on various conifer species indicate strong precipitation signatures in ring-width measurement series. The paucity of weather records from stations close to tree-ring sampling sites poses difficulty in calibrating tree-ring data against climate data especially precipitation for its strong spatial variability in mountain regions. However, for the existence of strong coherence in temperature, even in data from distant stations, more robust temperature reconstructions representing regional and hemispheric signatures have been developed. Tree-ring records from the region indicate multi-century warm and cool anomalies consistent with the Medieval Warm Period and Little Ice Age anomalies. Significant relationships noted between mean premonsoon temperature over the western Himalaya and ENSO features endorse utility of climate records from western Himalayan region in understanding long-term climate variability and attribution of anthropogenic impact.

  14. A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential.

    OpenAIRE

    Goudet, C; Vilar, B; Courtiol, T; Deltheil, T; Bessiron, T; Brabet, I; Oueslati, N; Rigault, D; Bertrand, HO; McLean, H; Daniel, H.; Amalric, M.; Acher, F.; Pin, JP

    2012-01-01

    Metabotropic glutamate (mGlu) receptors are promising targets to treat numerous brain disorders. So far, allosteric modulators are the only subtype selective ligands, but pure agonists still have strong therapeutic potential. Here, we aimed at investigating the possibility of developing subtype-selective agonists by extending the glutamate-like structure to hit a nonconsensus binding area. We report the properties of the first mGlu4-selective orthosteric agonist, derived from a virtual screen...

  15. Regional Glacier Sensitivity to Climate Change in the Monsoonal Himalaya: Implications for Water Resources

    Science.gov (United States)

    Rupper, S.; Maurer, J. M.; Schaefer, J. M.; Tsering, K.; Rinzin, T.; Dorji, C.; Johnson, E. S.; Cook, E. R.

    2014-12-01

    The rapid retreat of many glaciers in the monsoonal Himalaya is of potential societal concern. However, the retreat pattern in the region has been very heterogeneous, likely due in part to the inherent heterogeneity of climate and glaciers within the region. Assessing the impacts of glacier change on water resources, hydroelectric power, and hazard potential requires a detailed understanding of this potentially complex spatial pattern of glacier sensitivity to climate change. Here we quantify glacier surface-mass balance and meltwater flux across the entire glacierized region of the Bhutanese watershed using a full surface-energy and -mass balance model validated with field data. We then test the sensitivity of the glaciers to climatic change and compare the results to a thirty-year record of glacier volume changes. Bhutan is chosen because it (1) sits in the bulls-eye of the monsoon, (2) has >600 glaciers that exhibit the extreme glacier heterogeneity typical of the Himalayas, and (3) faces many of the economic and hazard challenges associated with glacier changes in the Himalaya. Therefore, the methods and results from this study should be broadly applicable to other regions of the monsoonal Himalaya. Our modeling results show a complex spatial pattern of glacier sensitivity to changes in climate across the Bhutanese Himalaya. However, our results also show that 90% of the total meltwater flux, and that these glaciers are uniformly the glaciers most sensitive to changes in temperature (and less sensitive to other climate variables). We compare these results to a thirty-year record of glacier volume changes over the same region. In particular, we extract DEMs and orthorectified imagery from 1976 historical spy satellite images and 2006 ASTER images. DEM differencing shows that the glaciers that have changed most over the past thirty years also have the highest modeled temperature sensitivity. These results suggest that, despite the complex glacier heterogeneity in the region, the regional meltwater resources are controlled by a very small percentage of the glaciers, and that these glaciers are particularly vulnerable to changes in temperature.

  16. Potential of biomass fuel conservation in selected Asian countries

    International Nuclear Information System (INIS)

    The potential of savings in the biomass consumed for energy in seven Asian countries--China, India, Pakistan, Nepal, Philippines, Sri Lanka and Vietnam--is estimated, if the centuries-old traditional methods of biomass use are reconsidered and an efficient, rational use is implemented. The present pattern and share of biomass consumption of different traditional biomass energy devices are recorded. The efficiency of traditional technologies and that of improved ones--technologies which are practically applicable or already in use somewhere else--are compared and the potential of biomass savings is calculated. The total biomass saving potential in all seven countries together has been estimated at 322 million tons/year. (Author)

  17. A study of algal biomass potential in selected Canadian regions.

    Energy Technology Data Exchange (ETDEWEB)

    Passell, Howard David; Roach, Jesse Dillon; Klise, Geoffrey T.

    2011-11-01

    A dynamic assessment model has been developed for evaluating the potential algal biomass and extracted biocrude productivity and costs, using nutrient and water resources available from waste streams in four regions of Canada (western British Columbia, Alberta oil fields, southern Ontario, and Nova Scotia). The purpose of this model is to help identify optimal locations in Canada for algae cultivation and biofuel production. The model uses spatially referenced data across the four regions for nitrogen and phosphorous loads in municipal wastewaters, and CO{sub 2} in exhaust streams from a variety of large industrial sources. Other data inputs include land cover, and solar insolation. Model users can develop estimates of resource potential by manipulating model assumptions in a graphic user interface, and updated results are viewed in real time. Resource potential by location can be viewed in terms of biomass production potential, potential CO{sub 2} fixed, biocrude production potential, and area required. The cost of producing algal biomass can be estimated using an approximation of the distance to move CO{sub 2} and water to the desired land parcel and an estimation of capital and operating costs for a theoretical open pond facility. Preliminary results suggest that in most cases, the CO{sub 2} resource is plentiful compared to other necessary nutrients (especially nitrogen), and that siting and prospects for successful large-scale algae cultivation efforts in Canada will be driven by availability of those other nutrients and the efficiency with which they can be used and re-used. Cost curves based on optimal possible siting of an open pond system are shown. The cost of energy for maintaining optimal growth temperatures is not considered in this effort, and additional research in this area, which has not been well studied at these latitudes, will be important in refining the costs of algal biomass production. The model will be used by NRC-IMB Canada to identify promising locations for both demonstration and pilot-scale algal cultivation projects, including the production potential of using wastewater, and potential land use considerations.

  18. Genesis of early Cambrian phosphorite of Krol Belt, Lesser Himalaya

    Digital Repository Service at National Institute of Oceanography (India)

    Mazumdar, A.; Banerjee, D.M.

    Early Cambrian phosphogenesis in the lesser Himalaya is represented by a well-developed sequence of phosphorite, black shale and black chert with interbedded phosphatic dolomite in the Krol Belt. Prevalence of shallow marine depositional structures...

  19. Are northeast and western Himalayas earthquake dynamics better “organized” than Central Himalayas: An artificial neural network approach

    OpenAIRE

    R.K. Tiwari; S.Sri Lakshmi

    2007-01-01

    The Himalaya covering 20-38° N latitude and 70-98° E longitude, is one of the most seismo-tectonically active and vulnerable regions of the world. Visual inspection of the temporal earthquake frequency pattern of the Himalayas indicates the nature of the tectonic activity prevailing in this region. However, the quantification of this dynamical pattern is essential for constraining a model and characterizing the nature of earthquake dynamics in this region. We examine the temporal evolution of...

  20. A novel approach for the potential parameters selection of Peyrard-Bishop model

    Energy Technology Data Exchange (ETDEWEB)

    Behnia, S., E-mail: s.behnia@iaurmia.ac.i [Department of Physics, IAU, Orumieh Branch, Orumieh (Iran, Islamic Republic of); Panahi, M.; Mobaraki, A. [Department of Physics, IAU, Orumieh Branch, Orumieh (Iran, Islamic Republic of); Akhshani, A. [Department of Physics, IAU, Orumieh Branch, Orumieh (Iran, Islamic Republic of); School of Physics, Universiti Sains Malaysia, 11800 USM, Penang (Malaysia)

    2011-02-14

    The selection of the potential parameters is a very difficult question because the potentials entering the model are effective potentials. In this Letter, an approach for selecting potential parameters of the Peyrard-Bishop model by mean Lyapunov exponent is presented. Using the theory introduced by Shibata [H. Shibata, Physica A 264 (1999) 226] on the Peyrard-Bishop model shows that, the system is very sensitive to the parameters selection. The obtained results demonstrate that the best range for parameters are where the mean Lyapunov exponent has low values. Furthermore, there is a good correspondence between our results and other reports.

  1. A novel approach for the potential parameters selection of Peyrard-Bishop model

    International Nuclear Information System (INIS)

    The selection of the potential parameters is a very difficult question because the potentials entering the model are effective potentials. In this Letter, an approach for selecting potential parameters of the Peyrard-Bishop model by mean Lyapunov exponent is presented. Using the theory introduced by Shibata [H. Shibata, Physica A 264 (1999) 226] on the Peyrard-Bishop model shows that, the system is very sensitive to the parameters selection. The obtained results demonstrate that the best range for parameters are where the mean Lyapunov exponent has low values. Furthermore, there is a good correspondence between our results and other reports.

  2. Prospects of Sustainable Livestock Farming in the Uttarakhand Himalaya, India

    Directory of Open Access Journals (Sweden)

    V. P. Sati

    2010-01-01

    Full Text Available Livestock farming forms an integral part in the economy of the Uttarakhand Himalaya and plays an important role in the mixed crop farming system. In addition, high diversity in livestock composition is the characteristic features of the mainland of Uttarakhand. The state obtains high potential of milk production because of availability of fodder as a form of extensive grasslands, which are locally known as bugyals or kharaks and fodder trees. Livestock, other than milk production, are widely used for manure, plowing fields and transportation of goods. The availability of extensive grasslands and feasible climatic conditions manifest a way for sustainable livestock farming in Uttarakhand, particularly in the temperate zone between 1400 m and 2200 m, where production of milk is high. Valley regions are generally known for rearing of drought animals with low milk producing capacity. This paper aims to discuss on the prospects of sustainable livestock farming and to trace the temporal changes that took place over the past years in terms of livestock population, composition, and the governmental policies and planning for developing livestock sector. It draws implications on these experiences for livestock planners and policy-makers and raises several research issues related to livestock sector development.

  3. Global warming may lead to catastrophic floods in the Himalayas

    International Nuclear Information System (INIS)

    In Nepal, data from 49 surveillance stations show that there has been a distinct temperature increase since the middle of the 1970s, the greatest changes being on the highest summits. When lakes overfill and beaches threaten to break down, this is a result of the global warming that melts the glaciers. The glaciers in Bhutan are observed to decrease by 30 - 40 metres per year, in some years as much as 100 metres. In the village of Tribeni an advanced warning system has been established to warn the 10 000 inhabitants of a potential flood from Lake Tsho Rolpa 108 km upstream. Research from the Himalayas also point to another serious threat. The melting threatens not only human lives, tourism, foot paths, roads, bridges and power stations. Since the mountains are the water towers of the world, filling rivers and lakes with water upon which all life depends, continued shrinking of the world's glaciers as is now observed will cause many rivers and fresh-water systems to dry out. Researchers from the UN Unep programme and International Centre for Integrated Mountain Development have registered at least 44 glacier lakes that are increasing so fast that they may cause outburst floods within five years. Similar investigations are being planned in India, Pakistan and China

  4. Review - Origins and Migrations in the Extended Eastern Himalayas

    Directory of Open Access Journals (Sweden)

    Jack Hayes

    2013-12-01

    Full Text Available Review of: Toni Huber and Stuart Blackburn (eds. 2012. Origins and Migrations in the Extended Eastern Himalayas. Leiden: Brill. Volume 16 in Brill's Tibetan Studies Library, This multidisciplinary anthology draws from papers presented at the international conference "Origins and Migrations Among TibetoBurman-Speakers of the Extended Eastern Himalaya" held at Humboldt University, Berlin in 2008. This collection of articles contributes to discussions surrounding the nature of and questions surrounding data, hypotheses, and theories of origins and migration in the 'extended Eastern Himalaya'. This region includes the hill peoples and territory ranging from eastern Nepal to Arunachal Pradesh, Nagaland, upland Southeast Asia and southwest China. Although there is some thematic overlap among the fourteen essays, they are quite a diverse lot, critically examining local and regional history, theoretical and methodological issues writ large, myths and rituals, society and social narrative, language and linguistic relationships, identity formation, and local-state dynamics related to local ideas about origins and migration. This book is particularly useful for gaining a better understanding of the issues linked to topics and theories of identity in the Eastern Himalaya (and wider Himalaya region more broadly considering the core importance of 'origins' in any construction or reconstruction of identity among diverse and widely spread communities. Graduate students and specialists...

  5. An approach for estimating the breach probabilities of moraine-dammed lakes in the Chinese Himalayas using remote-sensing data

    Directory of Open Access Journals (Sweden)

    X. Wang

    2012-10-01

    Full Text Available To make first-order estimates of the probability of moraine-dammed lake outburst flood (MDLOF and prioritize the probabilities of breaching posed by potentially dangerous moraine-dammed lakes (PDMDLs in the Chinese Himalayas, an objective approach is presented. We first select five indicators to identify PDMDLs according to four predesigned criteria. The climatic background was regarded as the climatic precondition of the moraine-dam failure, and under different climatic preconditions, we distinguish the trigger mechanisms of MDLOFs and subdivide them into 17 possible breach modes, with each mode having three or four components; we combined the precondition, modes and components to construct a decision-making tree of moraine-dam failure. Conversion guidelines were established so as to quantify the probabilities of components of a breach mode employing the historic performance method combined with expert knowledge and experience. The region of the Chinese Himalayas was chosen as a study area where there have been frequent MDLOFs in recent decades. The results show that the breaching probabilities (P of 142 PDMDLs range from 0.037 to 0.345, and they can be further categorized as 43 lakes with very high breach probabilities (P ? 0.24, 47 lakes with high breach probabilities (0.18 ? P < 0.24, 24 lakes with mid-level breach probabilities (0.12 ? P < 0.18, 24 lakes with low breach probabilities (0.06 ? P < 0.12, and four lakes with very low breach probabilities (p < 0.06.

  6. Can grass phytoliths and indices be relied on during vegetation and climate interpretations in the eastern Himalayas? Studies from Darjeeling and Arunachal Pradesh, India

    Science.gov (United States)

    Biswas, Oindrila; Ghosh, Ruby; Paruya, Dipak Kumar; Mukherjee, Biswajit; Thapa, Kishore Kumar; Bera, Subir

    2016-02-01

    While documenting the vegetation response to climatic changes in mountains, the use of grass phytolith data relies on the ability of phytolith assemblages or indices to differentiate the elevationally stratified vegetation zones. To infer the potential and limitations of grass phytolith assemblages and indices to reconstruct vegetation vis-à-vis climate in the Himalayan mountain regions, we analyzed phytolith assemblages from 66 dominant grasses and 153 surface soils from four different forest types along the c. 130-4000 m a.s.l. elevation gradients in the Darjeeling and Arunachal Himalayas. Grass short cell phytolith assemblages from modern grasses show significant variability with rising elevation. To test the reliability of the above observation, phytoliths from the soil samples were subjected to linear discriminant analysis (DA). DA classified 85.3% and 92.3% of the sites to their correct forest zones in the Darjeeling and Arunachal Himalayas respectively. Relative abundance of bilobate, cross, short saddle, plateau saddle, rondel and trapeziform types allow discrimination of the phytolith assemblage along the elevation gradient. Canonical correspondence analysis (CCA) on the soil phytolith data further revealed their relationships with the climatic variables. Temperature and evapotranspiration were found to be the most influential for differential distribution of grass phytolith assemblages with rising elevation in the eastern Himalayas. We also tested the reliability of phytolith indices (Ic, Iph and Fs) for tracing the dominance of different grass subfamilies in the eastern Himalayas. Ic proved to be most reliable in discriminating C3/C4 grass along the elevation gradient while Iph and Fs proved to be less reliable. We observed that in the monsoon dominated eastern Himalayas, a little adjustment in Ic index may enhance the accuracy of interpretations. In future studies more precise identification of phytolith sub-types from additional sites in the eastern Himalayas may further improve our interpretations related to past climate condition.

  7. Geographic Information System (GIS) as a Decision Support Tool for Selecting Potential Landfill Sites

    OpenAIRE

    Amakihe, Emeka

    2011-01-01

    One of the growing potential problems of increased consumption is an escalation in the quantities of municipal solid wastes produced. Landfilling is now accepted as the most widely used method for environmentally safe disposal of solid waste. However, appropriate site selection for waste disposal is one of the major problems in waste management. Selection of suitable landfills can be extremely complex mainly due to the fact that the selection process involves many factors, criteria and regula...

  8. Catastrophic landslide deposits in the karakoram himalaya.

    Science.gov (United States)

    Hewitt, K

    1988-10-01

    In July 1986, three catastrophic landslides deposited about 20 x 10(6) cubic meters of debris on Bualtar Glacier in the Karakoram Himalaya. A sudden acceleration and superficial breakup of the glacier provided an opportunity to examine the fresh deposits in depth. Beneath a surface layer of large boulders, finer materials, mainly sand and silt, made up half of the total volume. The fine materials were formed during the rock avalanche from mostly intact, massive rock of the source zone. Velocity estimates suggest that this disaggregation occurred in less than 2 minutes. Coarse materials remained in bands of uniform lithology, but the fine materials had diffused throughout the landslides. A small amount of carbonate appears to have been calcined by frictional heating, presumably at the base of the initial sliding masses. These observations are relevant to understanding the mechanisms of catastrophic landslides. Other nearby rock avalanche deposits indicate that landslides are an important geomorphic process in the area and that they pose a continuing risk to human activity. PMID:17757632

  9. Changing glacial lakes and associated outburst floods risks in Nanda Devi Biosphere Reserve, Indian Himalaya

    Science.gov (United States)

    Mal, S.; Singh, R. B.

    2014-09-01

    Glacial lakes and associated outburst floods (GLOFs) have increased in the Himalayan region due to climate change during the last century that has led to huge losses to society. Therefore, the present study was undertaken to map glacial lakes, their increasing extent, and associated damage potential in Nanda Devi Biosphere Reserve (NDBR), Indian Himalaya. The glacial lakes were mapped on Landsat TM (3 November, 2009 and 6 November 2010) and Landsat MSS satellite images (15 November 1976 and 26 October 1979) to assess their changing area. Potential GLOFs sites have been identified and studied for their damage potentials using site characteristics and past occurrence of GLOFs. A total of 35 lakes were mapped, of which 14 lakes are located at more than 4500 m. The size and damage potentials of lakes have increased. Some lakes grew so much that they merged to form a big lake. All of these are potential GLOFs and can cause severe damage to society.

  10. Atmospheric brown clouds reach the Tibetan Plateau by crossing the Himalayas

    Directory of Open Access Journals (Sweden)

    Z. L. Lüthi

    2015-06-01

    Full Text Available The Himalayas and the Tibetan Plateau region (HTP, despite being a remote and sparsely populated area, is regularly exposed to polluted air masses with significant amounts of aerosols including black carbon. These dark, light-absorbing particles are known to exert a great melting potential on mountain cryospheric reservoirs through albedo reduction and radiative forcing. This study combines ground-based and satellite remote sensing data to identify a severe aerosol pollution episode observed simultaneously in central Tibet and on the southern side of the Himalayas during 13–19 March 2009 (pre-monsoon. Trajectory calculations based on the high-resolution numerical weather prediction model COSMO are used to locate the source regions and study the mechanisms of pollution transport in the complex topography of the HTP. We detail how polluted air masses from an atmospheric brown cloud (ABC over South Asia reach the Tibetan Plateau within a few days. Lifting and advection of polluted air masses over the great mountain range is enabled by a combination of synoptic-scale and local meteorological processes. During the days prior to the event, winds over the Indo-Gangetic Plain (IGP are generally weak at lower levels, allowing for accumulation of pollutants and thus the formation of ABCs. The subsequent passing of synoptic-scale troughs leads to southwesterly flow in the middle troposphere over northern and central India, carrying the polluted air masses across the Himalayas. As the IGP is known to be a hotspot of ABCs, the cross-Himalayan transport of polluted air masses may have serious implications for the cryosphere in the HTP and impact climate on regional to global scales. Since the current study focuses on one particularly strong pollution episode, quantifying the frequency and magnitude of similar events in a climatological study is required to assess the total impact.

  11. Atmospheric brown clouds reach the Tibetan Plateau by crossing the Himalayas

    Science.gov (United States)

    Lüthi, Z. L.; Škerlak, B.; Kim, S.-W.; Lauer, A.; Mues, A.; Rupakheti, M.; Kang, S.

    2014-11-01

    The Himalayas and the Tibetan Plateau region (HTP), despite being a remote and sparsely populated area, is regularly exposed to polluted air masses with significant amounts of aerosols including black carbon. These dark, light-absorbing particles are known to exert a great melting potential on mountain cryospheric reservoirs through albedo reduction and radiative forcing. This study combines the available yet sparse ground-based and satellite data to identify a severe aerosol pollution episode observed simultaneously in central Tibet and on the southern side of the Himalayas during 13-19 March 2009. We detail how polluted air masses such as an atmospheric brown cloud (ABC) over South Asia reached the Tibetan Plateau during this pre-monsoon case study. In order to address the mechanisms of pollution transport in the complex topography of the HTP, air-mass trajectories are calculated using hourly outputs from the high-resolution numerical weather prediction model COSMO. Cross-mountain pollution transport is found to occur to a large extent at elevated tropospheric levels other than just through major river valleys. Lifting and advection of polluted air masses over the great mountain range is enabled by a combination of synoptic and local meteorological settings. Winds over the Indo Gangetic Plain (IGP) are generally weak at lower levels during the event, allowing for accumulation of pollutants. The passing of synoptic-scale troughs leads to south-westerly flow in the middle troposphere over northern and central India. Thus, ABC can build up south of the Himalayas and get carried northwards across the mountain range and onto the Tibetan Plateau as the winds obtain a southerly component. Air masses from the ABC hot-spot of the IGP can reach the high glaciers, which may have serious implications for the cryosphere in the HTP region and for climate on regional to global scales.

  12. Atmospheric brown clouds reach the Tibetan Plateau by crossing the Himalayas

    Science.gov (United States)

    Lüthi, Z. L.; Škerlak, B.; Kim, S.-W.; Lauer, A.; Mues, A.; Rupakheti, M.; Kang, S.

    2015-06-01

    The Himalayas and the Tibetan Plateau region (HTP), despite being a remote and sparsely populated area, is regularly exposed to polluted air masses with significant amounts of aerosols including black carbon. These dark, light-absorbing particles are known to exert a great melting potential on mountain cryospheric reservoirs through albedo reduction and radiative forcing. This study combines ground-based and satellite remote sensing data to identify a severe aerosol pollution episode observed simultaneously in central Tibet and on the southern side of the Himalayas during 13-19 March 2009 (pre-monsoon). Trajectory calculations based on the high-resolution numerical weather prediction model COSMO are used to locate the source regions and study the mechanisms of pollution transport in the complex topography of the HTP. We detail how polluted air masses from an atmospheric brown cloud (ABC) over South Asia reach the Tibetan Plateau within a few days. Lifting and advection of polluted air masses over the great mountain range is enabled by a combination of synoptic-scale and local meteorological processes. During the days prior to the event, winds over the Indo-Gangetic Plain (IGP) are generally weak at lower levels, allowing for accumulation of pollutants and thus the formation of ABCs. The subsequent passing of synoptic-scale troughs leads to southwesterly flow in the middle troposphere over northern and central India, carrying the polluted air masses across the Himalayas. As the IGP is known to be a hotspot of ABCs, the cross-Himalayan transport of polluted air masses may have serious implications for the cryosphere in the HTP and impact climate on regional to global scales. Since the current study focuses on one particularly strong pollution episode, quantifying the frequency and magnitude of similar events in a climatological study is required to assess the total impact.

  13. Atmospheric brown clouds reach the Tibetan Plateau by crossing the Himalayas

    Directory of Open Access Journals (Sweden)

    Z. L. Lüthi

    2014-11-01

    Full Text Available The Himalayas and the Tibetan Plateau region (HTP, despite being a remote and sparsely populated area, is regularly exposed to polluted air masses with significant amounts of aerosols including black carbon. These dark, light-absorbing particles are known to exert a great melting potential on mountain cryospheric reservoirs through albedo reduction and radiative forcing. This study combines the available yet sparse ground-based and satellite data to identify a severe aerosol pollution episode observed simultaneously in central Tibet and on the southern side of the Himalayas during 13–19 March 2009. We detail how polluted air masses such as an atmospheric brown cloud (ABC over South Asia reached the Tibetan Plateau during this pre-monsoon case study. In order to address the mechanisms of pollution transport in the complex topography of the HTP, air-mass trajectories are calculated using hourly outputs from the high-resolution numerical weather prediction model COSMO. Cross-mountain pollution transport is found to occur to a large extent at elevated tropospheric levels other than just through major river valleys. Lifting and advection of polluted air masses over the great mountain range is enabled by a combination of synoptic and local meteorological settings. Winds over the Indo Gangetic Plain (IGP are generally weak at lower levels during the event, allowing for accumulation of pollutants. The passing of synoptic-scale troughs leads to south-westerly flow in the middle troposphere over northern and central India. Thus, ABC can build up south of the Himalayas and get carried northwards across the mountain range and onto the Tibetan Plateau as the winds obtain a southerly component. Air masses from the ABC hot-spot of the IGP can reach the high glaciers, which may have serious implications for the cryosphere in the HTP region and for climate on regional to global scales.

  14. A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential.

    Science.gov (United States)

    Goudet, Cyril; Vilar, Bruno; Courtiol, Tiphanie; Deltheil, Thierry; Bessiron, Thomas; Brabet, Isabelle; Oueslati, Nadia; Rigault, Delphine; Bertrand, Hugues-Olivier; McLean, Heather; Daniel, Hervé; Amalric, Marianne; Acher, Francine; Pin, Jean-Philippe

    2012-04-01

    Metabotropic glutamate (mGlu) receptors are promising targets to treat numerous brain disorders. So far, allosteric modulators are the only subtype selective ligands, but pure agonists still have strong therapeutic potential. Here, we aimed at investigating the possibility of developing subtype-selective agonists by extending the glutamate-like structure to hit a nonconsensus binding area. We report the properties of the first mGlu4-selective orthosteric agonist, derived from a virtual screening hit, LSP4-2022 using cell-based assays with recombinant mGlu receptors [EC(50): 0.11 ± 0.02, 11.6 ± 1.9, 29.2 ± 4.2 ?M (n>19) in calcium assays on mGlu4, mGlu7, and mGlu8 receptors, respectively, with no activity at the group I and -II mGlu receptors at 100 ?M]. LSP4-2022 inhibits neurotransmission in cerebellar slices from wild-type but not mGlu4 receptor-knockout mice. In vivo, it possesses antiparkinsonian properties after central or systemic administration in a haloperidol-induced catalepsy test, revealing its ability to cross the blood-brain barrier. Site-directed mutagenesis and molecular modeling was used to identify the LSP4-2022 binding site, revealing interaction with both the glutamate binding site and a variable pocket responsible for selectivity. These data reveal new approaches for developing selective, hydrophilic, and brain-penetrant mGlu receptor agonists, offering new possibilities to design original bioactive compounds with therapeutic potential. PMID:22223752

  15. Taxonomic status of Bupleurum (Apiaceae in outer hills of Kashmir Himalayas, India

    Directory of Open Access Journals (Sweden)

    B. L. Bhellum

    2012-01-01

    Full Text Available Introduction: The genus Bupleurum is perennial rhizomatous herbs, recognized by simple leaves,conspicuous bracts and bractlets, often shows a great deal of variation in morphological characteristics. The genus is well developed in temperate and alpine zones of Kashmir Himalayas and other lesser Himalayan ranges of Jammu and Kashmir State. A key to the species, brief description, flowering and fruiting periods are given. The approximate elevation, distribution of species in the region andillustrations of selected species are provided.Material and Methods: The present communication is based on the surveys conducted between 1990 and 2007. The speciemens were mounted on the herbarium sheets and studied in the laboratory with the help of floristic literature.Results: As many as 10 species of genus Bupleurum have been recognized, from the different climaticzones of outer hills of Kashmir Himalayas of Jammu and Kashmir State.Conclusion: The report is first of its kind being communicated from the State of Jammu and Kashmir. Ten species of Bupleurum are described.

  16. Phase associations and potential selective extraction methods for selected high-tech metals from ferromanganese nodules and crusts with siderophores

    International Nuclear Information System (INIS)

    Highlights: • Phase associations of metals in marine Fe–Mn nodules and crusts were determined. • Selective leaching experiments with siderophore desferrioxamine B were conducted. • Siderophores selectively mobilize high-tech metals associated with Fe carrier phases. • Base metal liberation including Fe and Mn is limited. • Siderophores have promising potential for application in ore processing industries. - Abstract: Deep-sea ferromanganese deposits contain a wide range of economically important metals. Ferromanganese crusts and nodules represent an important future resource, since they not only contain base metals such as Mn, Ni, Co, Cu and Zn, but are also enriched in critical or rare high-technology elements such as Li, Mo, Nb, W, the rare earth elements and yttrium (REY). These metals could be extracted from nodules and crusts as a by-product to the base metal production. However, there are no proper separation techniques available that selectively extract certain metals out of the carrier phases. By sequential leaching, we demonstrated that, except for Li, which is present in an easily soluble form, all other high-tech metals enriched in ferromanganese nodules and crusts are largely associated with the Fe-oxyhydroxide phases and only to subordinate extents with Mn-oxide phases. Based on this fact, we conducted selective leaching experiments with the Fe-specific organic ligand desferrioxamine-B, a naturally occurring and ubiquitous siderophore. We showed by leaching of ferromanganese nodules and crusts with desferrioxamine-B that a significant and selective extraction of high-tech metals such as Li, Mo, Zr, Hf and Ta is possible, while other elements like Fe and the base metals Mn, Ni, Cu, Co and Zn are not extracted to large extents. The set of selectively extracted elements can be extended to Nb and W if Mn and carbonate phases are stripped from the bulk nodule or crust prior to the siderophore leach by e.g. a sequential leaching technique. This combination of sequential leaches with a siderophore leach enhanced the extraction to 30–50% of each Mo, Nb, W and Ta from a mixed type Clarion-Clipperton Zone (CCZ) nodule and 40–80% from a diagenetic Peru Basin nodule, whilst only 5–10% Fe and even less Mn are extracted from the nodules. Li is extracted to about 60% from the CCZ nodule and a maximum of 80% Li is extracted from the Peru Basin nodule. Our pilot work on selective extraction of high-tech metals from marine ferromanganese nodules and crusts showed that specific metal-binding organic ligands may have promising potential in future processing technologies of these oxide deposits

  17. 76 FR 27342 - Central Utah Project Completion Act; Notice of Intent To Accept Proposals, Select a Potential...

    Science.gov (United States)

    2011-05-11

    ... to not purchase and/or market the power generated by the hydropower development or such a decision... making a selection of a potential lessee. Interior will give more favorable consideration to proposals... decision regarding selection of the potential lessee(s). The selected potential lessee(s) will have...

  18. Structural control on along-strike variation in the seismicity of the northwest Himalaya

    Science.gov (United States)

    Arora, B. R.; Gahalaut, V. K.; Kumar, Naresh

    2012-09-01

    An overview of seismicity along the northwest Himalaya exhibit along-strike segmentation intricately controlled by the subsurface topographic ridges on the underthrusting Indian Plate as well by rift and nappe structures in the overriding wedge of the Himalaya. The segmentation exists for thrust dominated large magnitude earthquakes (M > 6) seated on the active detachment beneath the Outer and Lesser Himalaya. Segmentation also prevails for moderate and small magnitude earthquakes concentrated in a narrow Himalaya Seismic Belt (HSB) straddling northern Lesser Himalaya and southern Higher Himalaya. Numerical calculations of stress distribution favour that the degree of seismicity in the HSB is a good proxy to the presence of mid-crustal ramp connecting the locked section of active detachment to aseismically slipping detachment beneath Higher Himalaya. Further, gap or diffused pattern in the concentrated seismicity in the HSB, in agreement with mapped high electrical conductive structure, suggests ramp structure may be absent where underthrusting Delhi-Hardwar Ridge interacts with the Himalaya arc. In the nappe dominated tectonics, the accommodation of the accumulating strains on the listric thrust faults, produces increased frequency of moderate magnitude earthquakes and thereby possibly influences stress level on the detachment. This may explain relatively less frequent occurrences of large earthquake in the Kangra-Chamba region compared to that in the Garhwal Himalaya. The low level seismicity in the Simla region may also be influenced by the active Kaurik Chango Rift in the Higher Himalaya, as the former casts a stress shadow on the latter.

  19. Level of soil water potential as a tolerance selection environment for peanut to drought stress

    OpenAIRE

    Riadi, Muhammad; Soetopo, Lita; Nur Basuki; Kasno, Astanto

    2011-01-01

    A research was undertaken to determine level of soil water potential as a tolerance selection environment for peanut to drought stress. Result was that of 33 characters measured, 12 ones were selected to be further analyzed. Those characters were grain weight, pod weight, skin weight-percentage, number of filled-pod, number of unfilled-pod, weight of 100-grain, whole-plant weight, shoot weight, shoot-based harvest index, biomass-based harvest index, relative plant growth rate a...

  20. Selected constants oxidation-reduction potentials of inorganic substances in aqueous solution

    CERN Document Server

    Charlot, G; Marchon, M J C

    2013-01-01

    Selected Constants: Oxidation-reduction Potentials of Inorganic Substances in Aqueous Solution presents tables that will aid chemists in finding the best or most probable value of the normal or formal oxidation-reduction potential of oxidation-reduction systems. The book first presents numerical calculations that show the degree of oxidation and real oxidation-reduction systems, including the value of the potential, temperature, nature and composition of the medium, and the method of determination used. The text then takes a look at the choice of data, as well as intensity/potential curves an

  1. Potential site selection for radioactive waste repository using GIS (Study area: Negeri Sembilan) - Phase 1

    International Nuclear Information System (INIS)

    The main purpose in this paper is to create the Geographic Information System (GIS) based analysis on the potential site area for near-surface radioactive waste repository in the state of Negeri Sembilan. There are several parameters should be considered related to the safety assessment in selecting the potential site. These parameters such as land-use, urban area, soil, rainfall, lithology, lineament, geomorphology, landslide potential, slope, elevation, hydrogeology and protected land need to be considered before choosing the site. In this phase, we only consider ten parameters for determining the potential suitable site. (author)

  2. Energy Planning in Selected European Regions - Methods for Evaluating the Potential of Renewable Energy Sources

    OpenAIRE

    Sliz-Szkliniarz, Beata

    2013-01-01

    Given their potentially positive impact on climate protection and the preservation of fossil resources, alternative energy sources have become increasingly important for the energy supply over the past years. However, the questions arises what economic and ecological impacts and potential conflicts over land use resources are associated with the promotion of renewable energy production. Using the examples of three selected European Regions in Poland, France and German, the dissertation discus...

  3. Are northeast and western Himalayas earthquake dynamics better "organized" than Central Himalayas: An artificial neural network approach

    Scientific Electronic Library Online (English)

    S., Sri Lakshmi; R. K., Tiwari.

    2007-03-01

    Full Text Available Los Himalayas entre los 20 y 38 grados de latitud N y los 70 a 98 grados de longitud E están entre las regiones más activas y vulnerables a los temblores en el mundo. Se examina la evolución de la sismicidad en el tiempo (M > 4) en los Himalayas centrales, occidentales y del Noreste para el interval [...] o de 1960-2003 utilizando el método de redes neuronales artificiales (ANN). El modelo de capas múltiples sirve para simular la frecuencia de sismos con una resolución mensual. Para el entrenamiento del ANN se utiliza un algoritmo de propagación en reversa con optimización de gradiente, y se generaliza el resultado con validación cruzada. Se concluye que las tres regiones se caracterizan por procesos que evolucionan en un plano multidimensional caótico similar a una dinámica auto-organizada. El sector central posee un coeficiente de correlación más bajo que las otras dos regiones, que parecen estar mejor "organizadas", lo que es consistente con la información geológica y tectónica disponible. Abstract in english The Himalaya covering 20-38° N latitude and 70-98° E longitude, is one of the most seismo-tectonically active and vulnerable regions of the world. Visual inspection of the temporal earthquake frequency pattern of the Himalayas indicates the nature of the tectonic activity prevailing in this region. [...] However, the quantification of this dynamical pattern is essential for constraining a model and characterizing the nature of earthquake dynamics in this region. We examine the temporal evolution of seismicity (M > 4) of the Central Himalaya (CH), Western Himalaya (WH) and Northeast Himalaya (NEH), for the period of 1960-2003 using artificial neural network (ANN) technique. We use a multilayer feedforward artificial neural network (ANN) model to simulate monthly resolution earthquake frequency time series for all three regions. The ANN is trained using a standard back-propagation algorithm with gradient decent optimization technique and then generalized through cross-validation. The results suggest that earthquake processes in all three regions evolved on a high dimensional chaotic plane akin to "self-organized" dynamical pattern. Earthquake processes of NEH and WH show a higher predictive correlation coefficient (50-55%) compared to the CH (30%), implying that the earthquake dynamics in the NEH and WH are better "organized" than in the CH region. The available tectonogeological observations support the model predictions.

  4. Seismotectonics of the Kangra region, Northwest Himalaya

    Science.gov (United States)

    Kumar, S.; Mahajan, A. K.

    2001-02-01

    The occurrence of major and moderate earthquakes having thrust and strike-slip mechanism along the longitudinal and transverse feature within the same seismogenic zone requires us to study the area in detail to infer the seismotectonics. The epicentral distribution of earthquakes >4.0 (mb) between Chamba and Sundernagar region shows the high rate of activity either north of Chamba, i.e. north of the Main Central Thrust (MCT) or north of Dharamsala in between the Panjal Thrust (PT) and MCT in the Dhauladhar Range. It is, however, surprising that all the moderate earthquakes that have triggered in the Kangra region have either been in the frontal belt along the transverse features or have followed the arcuate belt close to the Main Boundary Thrust (MBT). The spatio-temporal variation of the seismicity from 1973 to 2000 (>4.0 mb) reveals a migration trend between Chamba and Sundernagar. During the seventies and early eighties, the seismicity was concentrated in the Chamba region and in the late eighties and early nineties, the seismicity shifted around Dharamsala and later further north. In this arcuate tectonic belt of the Chamba-Sundernagar region, the foreland region has a characteristic tectonic setting. All the fault and fold structures in the Oligocene-Miocene and Neogene-Pliestocene sediments in the foreland region show relative movement in the area of transverse tectonics. The surface structures, i.e. thinning and thickening of the sediments, are controlled by the basement cofiguration controlled by the subduction process. The MBT and the PT are closely spaced and meet each other just northwest of Dharamsala. The width of the Lesser Himalaya in the Chamba-Sundernagar region is also much narrower as compared to the region in the east, in Garhwal Kumaun and western Nepal. This suggests that the convergence is taken up largely by underthrusting of the Lesser Himalayan formations along the PT. The occurrence of a moderate earthquake of magnitude 6.5 in 1978 and the 1986 Dharamsala earthquake along the SE-dipping and SW-dipping nodal planes within the NE-dipping thrust regime and displacement of the MBT and PT from 4 to 12 km reflects the active involvement of the NE-SW trending fault system in controlling the seismic behavior of the Kangra region. The microearthquake migration in time and space in the Chamba-Sundernagar region also reflects the time differential segmental collision behavior of the basement.

  5. Selection of optimal recording sites for limited lead body surface potential mapping: A sequential selection based approach

    Directory of Open Access Journals (Sweden)

    McCullagh Paul J

    2006-02-01

    Full Text Available Abstract Background In this study we propose the development of a new algorithm for selecting optimal recording sites for limited lead body surface potential mapping. The proposed algorithm differs from previously reported methods in that it is based upon a simple and intuitive data driven technique that does not make any presumptions about deterministic characteristics of the data. It uses a forward selection based search technique to find the best combination of electrocardiographic leads. Methods The study was conducted using a dataset consisting of body surface potential maps (BSPM recorded from 116 subjects which included 59 normals and 57 subjects exhibiting evidence of old Myocardial Infarction (MI. The performance of the algorithm was evaluated using spatial RMS voltage error and correlation coefficient to compare original and reconstructed map frames. Results In all, three configurations of the algorithm were evaluated and it was concluded that there was little difference in the performance of the various configurations. In addition to observing the performance of the selection algorithm, several lead subsets of 32 electrodes as chosen by the various configurations of the algorithm were evaluated. The rationale for choosing this number of recording sites was to allow comparison with a previous study that used a different algorithm, where 32 leads were deemed to provide an acceptable level of reconstruction performance. Conclusion It was observed that although the lead configurations suggested in this study were not identical to that suggested in the previous work, the systems did bear similar characteristics in that recording sites were chosen with greatest density in the precordial region.

  6. Acoustic Noise Alters Selective Attention Processes as Indicated by Direct Current (DC) Brain Potential Changes

    OpenAIRE

    Karin Trimmel; Julia Schätzer; Michael Trimmel

    2014-01-01

    Acoustic environmental noise, even of low to moderate intensity, is known to adversely affect information processing in animals and humans via attention mechanisms. In particular, facilitation and inhibition of information processing are basic functions of selective attention. Such mechanisms can be investigated by analyzing brain potentials under conditions of externally directed attention (intake of environmental information) versus internally directed attention (rejection of environmental ...

  7. In Vitro and Ex Vivo Selection Procedures for Identifying Potentially Therapeutic DNA and RNA Molecules

    Directory of Open Access Journals (Sweden)

    Soledad Marton

    2010-06-01

    Full Text Available It was only relatively recently discovered that nucleic acids participate in a variety of biological functions, besides the storage and transmission of genetic information. Quite apart from the nucleotide sequence, it is now clear that the structure of a nucleic acid plays an essential role in its functionality, enabling catalysis and specific binding reactions. In vitro selection and evolution strategies have been extremely useful in the analysis of functional RNA and DNA molecules, helping to expand our knowledge of their functional repertoire and to identify and optimize DNA and RNA molecules with potential therapeutic and diagnostic applications. The great progress made in this field has prompted the development of ex vivo methods for selecting functional nucleic acids in the cellular environment. This review summarizes the most important and most recent applications of in vitro and ex vivo selection strategies aimed at exploring the therapeutic potential of nucleic acids.

  8. Event-related brain potentials in selective listening to frequent and rare stimuli.

    Science.gov (United States)

    Alho, K; Lavikainen, J; Reinikainen, K; Sams, M; Näätänen, R

    1990-01-01

    Our previous event-related brain potential (ERP) results suggest that during selective listening, relevant stimuli are selected for further processing by comparing each stimulus to an "attentional trace," a neuronal representation of the physical features of the relevant stimuli that distinguish them from the irrelevant stimuli. This comparison process is reflected by the early component of the processing negativity (PN), which is largest and longest to the relevant stimuli (perfectly matching with the trace). In the present study, the subjects selectively listened to designated tone stimuli which randomly appeared among irrelevant tones of a different pitch. The probability of relevant stimuli in a block was varied. The processing negativity elicited by relevant stimuli was smaller the less frequent they were. The results support the attentional-trace theory of selective attention, which proposes that, in addition to active maintenance, the trace also depends on the rate of sensory reinforcement provided by the relevant stimuli. PMID:2339190

  9. Morphometric analysis of Suketi river basin, Himachal Himalaya, India

    Indian Academy of Sciences (India)

    Anil M Pophare; Umesh S Balpande

    2014-10-01

    Suketi river basin is located in the Mandi district of Himachal Pradesh, India. It encompasses a central inter-montane valley and surrounding mountainous terrain in the Lower Himachal Himalaya. Morphometric analysis of the Suketi river basin was carried out to study its drainage characteristics and overall groundwater resource potential. The entire Suketi river basin has been divided into five sub-basins based on the catchment areas of Suketi trunk stream and its major tributaries. Quantitative assessment of each sub-basin was carried out for its linear, areal, and relief aspects. The analysis reveals that the drainage network of the entire Suketi river basin constitutes a 7th order basin. Out of five sub-basins, Kansa khad sub-basin (KKSB), Gangli khad sub-basin (GKSB) and Ratti khad sub-basin (RKSB) are 5th order subbasins. The Dadour khad sub-basin (DKSB) is 6th order sub-basin, while Suketi trunk stream sub-basin (STSSB) is a 7th order sub-basin. The entire drainage basin area reflects late youth to early mature stage of development of the fluvial geomorphic cycle, which is dominated by rain and snow fed lower order streams. It has low stream frequency (Fs) and moderate drainage density (Dd) of 2.69 km/km2. Bifurcation ratios (Rb) of various stream orders indicate that streams up to 3rd order are surging through highly dissected mountainous terrain, which facilitates high overland flow and less recharge into the subsurface resulting in low groundwater potential in the zones of 1st, 2nd, and 3rd order streams of the Suketi river basin. The circulatory ratio (Rc) of 0.65 and elongation ratio (Re) of 0.80 show elongated nature of the Suketi river basin, while infiltration number (If) of 10.66 indicates dominance of relief features and low groundwater potential in the high altitude mountainous terrain. The asymmetry factor (Af) of Suketi river basin indicates that the palaeo-tectonic tilting, at drainage basin scale, was towards the downstream right side of the drainage basin. The slope map of Suketi river basin has been classified into three main zones, which delineate the runoff zone in the mountains, recharge zone in the transition zone between mountains and valley plane, and discharge zone in the plane areas of Balh valley.

  10. Cycles of Sediment Aggradation and Incision in the Western Sub-Himalaya

    Science.gov (United States)

    Dey, Saptarshi; Thiede, Rasmus; Bookhagen, Bodo; Strecker, Manfred

    2013-04-01

    The magnitude of sediment delivery from the Himalayan mountains to the foreland, is characterized by large fluctuations on different timescales. At the first order, these fluctuations are manifested by periods of sediment aggradation, associated with the formation of large alluvial fans during times of high sediment delivery and re-incision and remobilization during reduced sediment delivery. At longer timescale (106-107 yr) sediment delivery is controlled by tectonic processes, whereas at shorter timescales (103-105 yr) climatic fluctuations such as variations in monsoonal strength or Quaternary glacial and interglacial oscillations dictate sediment production and transport. However, detailed stratigraphic information and chronologies of Quaternary sediment aggradation and incision cycles within the Sub-Himalaya are lacking and the degree of variability in sediment delivery during these episodes has remained unclear. In this study, we investigate Quaternary sediments exposed within the Sub-Himalaya of the Kangra re-entrant to the west of the Beas river. Here, the outlets of the drainage basins provide an ideal location to analyze aggradation and re-incision of transiently-stored sediments. The sediment-source region for this area is the Dhauladhar range, in the Higher Himalaya, which has been uplifting since the Late Miocene, thus restricting the potential source region for Late Cenozoic sediments supplied to the foreland. Folded and faulted Siwalik sediments of the Sub-Himalaya have formed sediment-filled intramontane piggy-back basin and have been progressively excavated. Thus far, we document a prolonged sediment-aggradation period by a thick sequence of boulder conglomerates. Subsequent re-incision of this fill, has left atleast three distinct terrace levels, which are recognized regionally at elevations ~5-10m, 65±10m and 140±10m above the present-day riverbed. The composition of the fill unit is dominated by 60% granitic clasts and is therefore distinct from the regionally exposed Siwalik conglomerates (>65% quartzite). We interpret the provenance signal to mean that the exposed lithologies in the catchment most likely had changed from quartzite-rich Higher Himalayan cover units to unroofed granites between the time of deposition of the Upper Siwalik conglomerates and sedimentary basin fill. Preliminary river profile analyses and topographic profiles along the terrace surfaces revealed tilting of some of the older, higher terrace levels in certain sections towards the north-east when compared to the gradient of the present-day river, suggesting ongoing internal shortening within the Sub-Himalaya. DEM-based geomorphic analysis, surface exposure dating and burial dating of well-shielded sediments using cosmogenic nuclides are in progress. With the expected results, we anticipate to determine the chronology of terrace levels, determine deformation rates, reconstruct the fluvial incision history and ultimately the minimum sediment-flux rate in the study area.

  11. Considering Future Potential Regarding Structural Diversity in Selection of Forest Reserves

    Science.gov (United States)

    Lundström, Johanna; Öhman, Karin; Rönnqvist, Mikael; Gustafsson, Lena

    2016-01-01

    A rich structural diversity in forests promotes biodiversity. Forests are dynamic and therefore it is crucial to consider future structural potential when selecting reserves, to make robust conservation decisions. We analyzed forests in boreal Sweden based on 17,599 National Forest Inventory (NFI) plots with the main aim to understand how effectiveness of reserves depends on the time dimension in the selection process, specifically by considering future structural diversity. In the study both the economic value and future values of 15 structural variables were simulated during a 100 year period. To get a net present structural value (NPSV), a single value covering both current and future values, we used four discounting alternatives: (1) only considering present values, (2) giving equal importance to values in each of the 100 years within the planning horizon, (3) applying an annual discount rate considering the risk that values could be lost, and (4) only considering the values in year 100. The four alternatives were evaluated in a reserve selection model under budget-constrained and area-constrained selections. When selecting young forests higher structural richness could be reached at a quarter of the cost over almost twice the area in a budget-constrained selection compared to an area-constrained selection. Our results point to the importance of considering future structural diversity in the selection of forest reserves and not as is done currently to base the selection on existing values. Targeting future values increases structural diversity and implies a relatively lower cost. Further, our results show that a re-orientation from old to young forests would imply savings while offering a more extensive reserve network with high structural qualities in the future. However, caution must be raised against a drastic reorientation of the current old-forest strategy since remnants of ancient forests will need to be prioritized due to their role for disturbance-sensitive species. PMID:26866480

  12. Environmental change and challenge in the Himalaya. A historical perspective

    Directory of Open Access Journals (Sweden)

    Ives, Jack D.

    2012-05-01

    Full Text Available This overview, or retrospective, has two objectives. The first is to demonstrate how the principles of ‘mountain geoecology’ were applied in an attempt to counteract the political and socio-economic impacts of a major and misguided environmental orthodoxy-the Theory of Himalayan Environmental Degradation (henceforth to be referred to as the ‘Theory’. The second is to explore the difficulties of transferring the results of on-going scholarly mountain research into the public and political decision-making process. In this sense the paper should be regarded as a case study of the potentially serious effects of exaggerated and emotionally based responses to orthodoxies founded on assumptions and latter-day myths. A third objective, reserved for the companion paper in this issue, outlines the origins of mountain geoecology and explores how academic research influenced the inclusion of high level concern for mountain problems within AGENDA 21, one of the principal results of the 1992 UN Conference on Environment and Development (popularly known as the Rio Earth Summit and declaration of 2002 as the International Year of Mountains. The original environmental orthodoxy (the Theory has been eclipsed since the turn of the Millennium by a new populist alarm proposing that the current climate warming will cause all the Himalayan glaciers to disappear in the near future. From this it would follow that, as the glacier melt progresses, numerous large glacial lakes, forming as a consequence, would burst and the ensuing floods would annihilate many millions of people. Eventually, as the glaciers disappeared vital rivers, such as the Ganges and Brahmaputra, would wither to seasonal streams heralding further massive loss of life due to desertification and starvation. This current environmental alarm could be regarded as a present day parallel to the original Theory and will be examined in the final section of the paper. Between 1970 and about 1985 it was almost universal wisdom amongst scholars and development specialists, as well as conservationists, that the Himalaya were on the brink of environmental, and hence socio-economic and political collapse. This theme of gloom and doom was taken up avidly by journalists, politicians, and diplomats; it influenced the expenditure of large sums of aid and development money, and augmented periodic international confrontations. In concise terms, in the early 1970s an assumed approaching environmental disaster was perceived to be driven by relentless growth in the population of subsistence hill communities and their dependence on mountain forests for fuel, fodder, building materials, and conversion to agricultural land. The assumption of rapid and catastrophic deforestation of steep hillslopes under a monsoon climate (the World Bank predicted that there would be no accessible forest remaining in Nepal by the year 2000 led inexorably to a series of dependent assumptions: increasing soil erosion and worsening landslide incidence; accelerated flooding and siltation on the plains of Gangetic India and Bangladesh; social and political unrest, if not serious armed conflict – the notion of a world super-crisis, considering that the region in question contained about ten percent of the world’s entire human population and about thirty percent of its poorest. As will be emphasized later, none of this all-embracing construct was based on reliable evidence, but it was accepted world-wide as a given. It represents a prime example of the dangers associated with convenient adoption of environmental myths, or environmental orthodoxies, especially where the myth is a Western ‘scientific’ construct. I characterized it as The Theory of Himalayan Environmental Degradation (Ives, 1985.Esta perspectiva global, o retrospectiva, tiene dos objetivos. El primero es demostrar cómo se aplicaron los principios de la “geoecología de montaña” en un intento por contrarrestar los impactos políticos y socioeconómicos de una errónea ortodoxia ambiental, la Teoría de la Degradación Ambiental del Himalaya (en adelante referida como la “Teoría”. El segundo es explorar las dificultades para transferir los resultados de la investigación científica en montaña a los procesos públicos de decisión. En este sentido, el artículo debería ser contemplado como un estudio de caso de los efectos potencialmente serios de las exageradas respuestas a las ortodoxias basadas en suposiciones y mitos de última hora. Un tercer objetivo, reservado a otro trabajo publicado en este volumen, subraya los orígenes de la geoecología de montaña y explora cómo la investigación académica influyó en la incorporación de la preocupación por los problemas de la montaña en la AGENDA 21, uno de los principales resultados de la Conferencia de Naciones Unidas de 1992 sobre Medio Ambiente y Desarrollo (popularmente conocida como la Cumbre de Río, y la declaración de 2002 como el Año Internacional de las Montañas. La ortodoxia ambiental original (la Teoría ha sido eclipsada desde el cambio de milenio por una nueva alarma populista que propone que el actual calentamiento climático hará que todos los glaciares del Himalaya desaparezcan en un futuro próximo. De ahí puede deducirse que, a medida que la fusión glaciar progrese, numerosos lagos glaciares reventarían y las consiguientes avenidas aniquilarían a millones de personas. Eventualmente, tras la desaparición de los glaciares, algunos ríos fundamentales, como el Ganges y el Brahmaputra podrían convertirse en ríos estacionales ocasionando la pérdida masiva de vidas humanas debido a la desertificación y el hambre. Esta alarma ambiental podría ser vista como paralela a la Teoría original, y será examinada en la parte final de este artículo. Entre 1970 y 1985 se mantuvo la opinión entre los científicos y especialistas en desarrollo, así como entre los conservacionistas, de que el Himalaya estaba al borde del colapso ambiental, socioeconómico y político. Este pesimismo y predestinación fue adoptado ávidamente por periodistas, políticos y diplomáticos, e influyó en la dedicación de grandes sumas de dinero y ayudas. En pocas palabras, a comienzos de los años setenta se asumió la ocurrencia de un desastre ambiental determinado por el crecimiento demográfico de comunidades que dependían de los bosques de montaña para la obtención de energía, forraje, materiales de construcción y expansión de los terrenos agrícolas. La asunción de una rápida y catastrófica deforestación de laderas pendientes bajo clima monzónico (el Banco Mundial predijo que no habría bosques accesibles en Nepal hacia el año 2000 condujo inexorablemente a aceptar otras suposiciones: aumento de la erosión del suelo y acentuación de la incidencia de los deslizamientos; incremento de la magnitud y frecuencia de las avenidas y del transporte de sedimento en las llanuras del Ganges en India y Bangladesh; conflictividad social y política, cuando no serios conflictos armados, es decir, la noción de una supercrisis mundial, teniendo en cuenta que la región en cuestión contiene alrededor del 10 por ciento de la población mundial y alrededor de la tercera parte de los más pobres. Como se pone de relieve a continuación, ninguna de esas ideas se basaba en evidencias fiables, pero fueron aceptadas mundialmente como un hecho. Representan un ejemplo claro de los peligros asociados a la adopción de mitos u ortodoxias ambientales, especialmente donde el mito es una construcción “científica” del mundo occidental. Yo la definí como la Teoría de la Degradación Ambiental del Himalaya (Ives, 1985.

  13. Six hitherto unreported Basidiomycetic macrofungi from Kashmir Himalayas

    Directory of Open Access Journals (Sweden)

    MOHMAD YAQUB BHAT

    2011-07-01

    Full Text Available Pala SA, Wani AH, Bhat MY. 2011. Six hitherto unreported Basidiomycetic macrofungi from Kashmir Himalayas. Nusantara Bioscience 3: 92-97. The Kashmir valley located in the north extreme of the India lies between 33020’ and 34054’ N latitude and 730 55’ and 75035’ E longitude. The forests constituting more than 20% of the geographical area harbors diverse macrofungal species due to their wide variability in climate altitude and nature of species constituting them. The mushroom flora of the Kashmir Valley has not been documented completely until now. In this backdrop, a systematic survey for exploration and inventorization of macrofungal species of Western Kashmir Himalaya was undertaken during the year 2009-2010. During the study six species viz. Agrocybe molesta, Coprinus plicatilis, Inonotus hispidus, Paxillus involutus, Psathyrella candolleana and Russula fragilis were identified first time from the Kashmir.

  14. Northward genetic penetration across the Himalayas viewed from Sherpa people.

    Science.gov (United States)

    Kang, Longli; Wang, Chuan-Chao; Chen, Feng; Yao, Dali; Jin, Li; Li, Hui

    2016-01-01

    The Himalayas have been suggested as a natural barrier for human migrations, especially the northward dispersals from the Indian Subcontinent to Tibetan Plateau. However, although the majority of Sherpa have a Tibeto-Burman origin, considerable genetic components from Indian Subcontinent have been observed in Sherpa people living in Tibet. The western Y chromosomal haplogroups R1a1a-M17, J-M304, and F*-M89 comprise almost 17% of Sherpa paternal gene pool. In the maternal side, M5c2, M21d, and U from the west also count up to 8% of Sherpa people. Those lineages with South Asian origin indicate that the Himalayas have been permeable to bidirectional gene flow. PMID:24617465

  15. Integrated Natural Resource Management: Approaches and Lessons from the Himalaya

    Directory of Open Access Journals (Sweden)

    R. K. Maikhuri

    2002-01-01

    Full Text Available Losses of forest cover, biodiversity, agricultural productivity, and ecosystem services in the Himalayan mountain region are interlinked problems and threats to the sustainable livelihoods of 115 x 106 mountain people as well as the inhabitants of the adjoining Indo-gangetic plains. Until the 1970s, environmental conservation, food security, and rural economic development were treated as independent sectors. The poor outcomes of sector-oriented approaches catalyzed efforts to address environmental and socioeconomic problems concurrently. The identification of "key" natural resource management interventions is an important dimension of integrated management. Projects to rehabilitate the degraded lands that cover 40% of the Indian Himalaya could be key interventions provided that they address both socioeconomic and environmental concerns across spatial and temporal scales. However, projects of this type, e.g., investments in conifer plantations on degraded forest lands, have failed because their designs did not take into account the needs of local residents. This study illustrates a case of land rehabilitation in a small isolated village close to the alpine zone. Vital elements of this project strategy included identifying local perceptions and knowledge and involving the local people in the selection and implementation of the interventions needed to restore the land. Communities were found to be more concerned with the immediate economic benefits from bamboo and medicinal species than the long-term benefits of tree planting. The villagers eventually reached a consensus to plant broadleaved multipurpose trees in association with bamboo and medicinal species. Despite assurances that all the economic benefits from rehabilitation would go to the community, the people would not agree to voluntary labor, although they did absorb significant costs by providing social fencing, farmyard manure, and propagules from community forests. Households shared costs and benefits according to traditional norms. The economic benefits to the local people exceeded the rehabilitation cost over the 7-yr life of the project. There were significant on-site environmental benefits in terms of improvements in soil fertility, biodiversity, protective cover, and carbon sequestration, and off-site benefits from more productive use of labor, reduced pressure on protected areas, and the introduction of rare and threatened medicinal species onto private farmland.

  16. Ethnobotanical uses of Biofencing Plants in Himachal Pradesh, Northwest Himalaya

    OpenAIRE

    Pankaj Sharma3; Usha Devi

    2013-01-01

    The aim of this study is to document the traditional knowledge on the utilization of Biofencing plants of Himachal Pradesh, Northwest Himalaya. The study was imperative because of dearth in the data pertaining to Biofencing plants in the study areas. The whole study area was stratified into three zones and a widespread field survey and random sampling method was adopted to assess the live fencing diversity of the region. The region occupies total 61 species. 10 (trees), 45 (shrubs), 4 (herbs)...

  17. Fuelwood consumption pattern at different altitudes in Garhwal Himalaya

    International Nuclear Information System (INIS)

    We analyse firewood consumption along altitudinal gradient by households according to their socio-economic conditions in Garhwal Himalaya. Consumption of fuelwood was 789, 664, 518, and 544 kg/cap-yr and energy consumption for fuelwood collection was 41, 53, 52 and 80 x 103 kg/cap-yr, respectively, above 2000, for 1500-2000, 1000-1500, and 500-1000 m. Commercial fuel consumption constituted 0.6-4.5%. (author)

  18. Distribution Characteristics of the Tree Species in Central Himalaya, India

    OpenAIRE

    Geeta Kharkwal; Yaswant Singh Rawat; Yaspal Singh Pangtey

    2007-01-01

    A total of 257 tree species were recorded and studied for their pattern and altitudinal distribution in Central Himalaya. Relatively higher percentage (65%) of deciduous species was recorded. Distribution of tree species in this region is between <200-4200 m asl. However, maximum (60%) species were found either below or at around 1500 m asl altitudes may be due to overlapping of species. Lauraceae and Anacardiaceae are the dominant families in both forms. Species richness declines graduall...

  19. Treeline dynamics with climate change at the central Nepal Himalaya

    OpenAIRE

    Gaire, N. P.; Koirala, M.; D. R. Bhuju; H. P. Borgaonkar

    2014-01-01

    Treeline shifting in tandem with climate change has widely been reported from various parts of the world. In Nepal, several impacts of climate change on the physical environment have been observed, but study on the biological impacts is lacking. This dendrochronological study was carried out at the treeline in the high mountain slope of Kalchuman Lake (3750–4003 m a.s.l.) area of Manaslu Conservation Area in the central Nepal Himalaya to explore the impact of climate change ...

  20. Electrical resistivity imaging of seismically active frontal Himalaya

    International Nuclear Information System (INIS)

    Complete text of publication follows. Given the sensitivity of resistivity to rheology, magnetotelluric measurement are undertaken to study deep crustal electrical structures and their possible linkage to the space-depth distribution of seismicity. Magnetotelluric investigations at Thirty three sites along Bijnaur-Mallari profile cutting across major litho tectonic units of Himalaya starting from Indo Ganges plain, Siwalik, Lesser, Higher Himalaya to Tethys Himalaya. Observing the low solar activity during the survey period each site was occupied for five days. Longer occupancy allowed estimation of impedance tensor at periods greater than 500 sec at most of the stations. However at few stations electric field recordings were very noisy perhaps due to unbalanced power network of the region. This is reflected in larger error bars in estimated impedance tensors. Skewness and other dimensionality parameter indicate the validity of 2-D regional model. Robust impedance decomposition for the period band of 10 Hz- 1000 sec of eleven stations reveal that EM strike coincides with the geologic fabric. Considering regional strike EM field were decoupled in TE, TM mode and then inverted for frequency dependent conductivity distribution along the profile. The most conspicuous feature of the inverted resistivity section is the low resistivity zone at a shallow depth of 10 km beneath the Indo-Gangetic Plains that dips down at a low-angle and extends as a continuous plane right up to the northern limit of the profile. The geometry of this layer is correlated with the basement thrust separating the top of the under thrusting Indian Plate from the over-riding sedimentary wedge of lesser Himalaya. The paper will discuss the tectonic and rheological significance of the results of resistivity imaging using magnetotelluric method along the profile from Bijnaur to Mallari.

  1. Crossmodal effects of Guqin and piano music on selective attention: an event-related potential study.

    Science.gov (United States)

    Zhu, Weina; Zhang, Junjun; Ding, Xiaojun; Zhou, Changle; Ma, Yuanye; Xu, Dan

    2009-11-27

    To compare the effects of music from different cultural environments (Guqin: Chinese music; piano: Western music) on crossmodal selective attention, behavioral and event-related potential (ERP) data in a standard two-stimulus visual oddball task were recorded from Chinese subjects in three conditions: silence, Guqin music or piano music background. Visual task data were then compared with auditory task data collected previously. In contrast with the results of the auditory task, the early (N1) and late (P300) stages exhibited no differences between Guqin and piano backgrounds during the visual task. Taking our previous study and this study together, we can conclude that: although the cultural-familiar music influenced selective attention both in the early and late stages, these effects appeared only within a sensory modality (auditory) but not in cross-sensory modalities (visual). Thus, the musical cultural factor is more obvious in intramodal than in crossmodal selective attention. PMID:19766172

  2. Tectonic and polymetamorphic history of the Lesser Himalaya in central Nepal

    Science.gov (United States)

    Paudel, Lalu Prasad; Arita, Kazunori

    2000-04-01

    The Lesser Himalaya in central Nepal consists of Precambrian to early Paleozoic, low- to medium-grade metamorphic rocks of the Nawakot Complex, unconformably overlain by the Upper Carboniferous to Lower Miocene Tansen Group. It is divided tectonically into a Parautochthon, two thrust sheets (Thrust sheets I and II), and a wide shear zone (Main Central Thrust zone) from south to north by the Bari Gad-Kali Gandaki Fault, the Phalebas Thrust and the Lower Main Central Thrust, respectively. The Lesser Himalaya is overthrust by the Higher Himalaya along the Upper Main Central Thrust (UMCT). The Lesser Himalaya forms a foreland-propagating duplex structure, each tectonic unit being a horse bounded by imbricate faults. The UMCT and the Main Boundary Thrust are the roof and floor thrusts, respectively. The duplex is cut-off by an out-of-sequence fault. At least five phases of deformation (D 1-D 5) are recognized in the Lesser Himalaya, two of which (D 1 and D 2) belong to the pre-Himalayan (pre-Tertiary) orogeny. Petrographic, microprobe and illite crystallinity data show polymetamorphic evolution of the Lesser and Higher Himalayas in central Nepal. The Lesser Himalaya suffered a pre-Himalayan (probably early Paleozoic) anchizonal prograde metamorphism (M 0) and a Neohimalayan (syn- to post-UMCT) diagenetic to garnet grade prograde inverted metamorphism (M 2). The Higher Himalaya suffered an Eohimalayan (pre or early-UMCT) kyanite-grade prograde metamorphism (M 1) which was, in turn, overprinted by Neohimalayan (syn-UMCT) retrograde metamorphism (M 2). The isograd inversion from garnet zone in the Lesser Himalaya to kyanite zone in the Higher Himalaya is only apparent due to post-metamorphic thrusting along the UMCT. Both the Lesser and Higher Himalayas have undergone late-stage retrogression (M 3) during exhumation.

  3. Identifying Potential Clinical Syndromes of Hepatocellular Carcinoma Using PSO-Based Hierarchical Feature Selection Algorithm

    OpenAIRE

    Zhiwei Ji; Bing Wang

    2014-01-01

    Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Clinical symptoms attributable to HCC are usually absent, thus often miss the best therapeutic opportunities. Traditional Chinese Medicine (TCM) plays an active role in diagnosis and treatment of HCC. In this paper, we proposed a particle swarm optimization-based hierarchical feature selection (PSOHFS) model to infer potential syndromes for diagnosis of HCC. Firstly, the hierarchical feature representation is developed...

  4. Selection of potential probiotic lactic acid bacteria from fermented olives by in vitro tests

    OpenAIRE

    Argyri, Anthoula; Zoumpopoulou, Georgia; Karatzas, Kimon Andreas; Tsakalidou, Effie; Nychas, George John; Panagou, Efstathios; Tassou, Chrysoula

    2012-01-01

    The present study aims to evaluate the probiotic potential of lactic acid bacteria (LAB) isolated from naturally fermented olives and select candidates to be used as probiotic starters for the improvement of the traditional fermentation process and the production of newly added value functional foods. Seventy one (71) lactic acid bacterial strains (17 Leuconostoc mesenteroides, 1 Ln. pseudomesenteroides, 13 Lactobacillus plantarum, 37 Lb. pentosus, 1 Lb. paraplantarum, and 2 Lb. paracasei sub...

  5. Selection of potential autochthonous starter cultures from shalgam, a traditional Turkish lactic acid-fermented beverage

    OpenAIRE

    ERTEN, Hasan TANGÜLER Hüseyin

    2013-01-01

    The present study was done to select the potential autochthonous lactic acid bacteria (LAB) for the production of shalgam, which is a traditional Turkish lactic acid-fermented beverage. Eighteen LAB belonging to the genera Lactobacillus, Lactococcus, Pediococcus, and Leuconostoc isolated previously from shalgam samples produced in the university laboratory and by small- and large-scale producers in industry were used. Pasteurized black carrot juice was inoculated individually with these selec...

  6. Selection and characterization of potential probiotic bacteria for Litopenaeus stylirostris shrimp hatcheries in New Caledonia

    OpenAIRE

    Pham, Dominique; Ansquer, Dominique; Chevalier, Anne; Dauga, Clement; Peyramale, Aude; Wabete, Nelly; Labreuche, Yannick

    2014-01-01

    In New Caledonia, shrimp hatcheries are confronted with mass mortality in the larval stages, a phenomenon poorly understood as no specific causative agent has been identified. This has resulted in an excessive use of prophylactic antibiotics, although their adverse effects in aquaculture are notorious. The present work was thus aimed at selecting potential probiotic strains for penaeid hatcheries. From a pool of more than 400 marine bacterial isolates sampled from the local marine environ...

  7. Non-selective cation channels, transient receptor potential channels and ischemic stroke

    OpenAIRE

    Simard, J Marc; Tarasov, Kirill V; Gerzanich, Volodymyr

    2007-01-01

    Several pathways to neural cell death are involved in ischemic stroke, and all require monovalent or divalent cation influx, implicating non-selective cation (NC) channels. NC channels are also likely to be involved in the dysfunction of vascular endothelial cells that leads to formation of edema following cerebral ischemia. Two newly described NC channels have emerged as potential participants in ischemic stroke, the acid sensing ion channel (ASIC), and the sulfonylurea receptor-1 (SUR1)-reg...

  8. Evaluation of mitochondrial membrane potential using a computerized device with a tetraphenylphosphonium-selective electrode.

    Czech Academy of Sciences Publication Activity Database

    Labajová, A.; Vojtíšková, Alena; K?iváková, P.; Kofránek, J.; Drahota, Zden?k; Houšt?k, Josef

    2006-01-01

    Ro?. 353, ?. 1 (2006), s. 37-42. ISSN 0003-2697 R&D Projects: GA ?R(CZ) GD303/03/H065; GA ?R(CZ) GA303/06/1261 Grant ostatní: GA UK(CZ) 126/04/C; IGA MŠk(CZ) RP 394 Institutional research plan: CEZ:AV0Z50110509 Keywords : membrane potential * TPP-selective electrode Subject RIV: CE - Biochemistry Impact factor: 2.948, year: 2006

  9. Characterization of N200 and P300: Selected Studies of the Event-Related Potential

    OpenAIRE

    Patel, Salil H.; Azzam, Pierre N.

    2005-01-01

    The Event-Related Potential (ERP) is a time-locked measure of electrical activity of the cerebral surface representing a distinct phase of cortical processing. Two components of the ERP which bear special importance to stimulus evaluation, selective attention, and conscious discrimination in humans are the P300 positivity and N200 negativity, appearing 300 ms and 200 ms post-stimulus, respectively. With the rapid proliferation of high-density EEG methods, and interdisciplinary interest in its...

  10. Radon as an earthquake precursor in NW Himalayas, India

    Science.gov (United States)

    Kumar, Arvind; Singh, Surinder; Singh Bajwa, Bikramjit; Mahajan, Sandeep; Dhar, Sunil; Walia, Vivek

    2010-05-01

    The continuous soil gas radon and daily monitoring of radon concentration in water is carried out at Amritsar (Punjab), Kangra and Chamba Valleys of NW Himalayas India to study the correlation of radon anomalies in relation to seismic activities in the region. In this study, radon monitoring in soil was carried out by using barasol probe manufactured by Algade France whereas the radon content in water was recorded using RAD7 radon monitoring system of Durridge Company USA. The radon anomalies observed in the region have been correlated with the seismic events of M ? 2 recorded in NW Himalayas by Wadia Institute of Himalayas Geology Dehradoon and Indian Meteorological Department, New Delhi. The effect of meteorological parameters viz. temperature, pressure, wind velocity and rainfall on radon emission has been studied. The correlation coefficient between radon and meteorological parameters has been evaluated. The equation for the correction of these correlations to obtain a corrected radon concentration that shows less variability is derived. Empirical equations between earthquake magnitude, epicentral distance and precursor time have been examined and respective constants were determined

  11. Mass movement in the Himalaya: new insights and research directions

    Science.gov (United States)

    Shroder, John F.; Bishop, Michael P.

    1998-12-01

    Ongoing studies that relate tectonics to the processes at the surface of Earth show that many more sources of information about agents of shallow denudation, such as mass movement, are required to comprehend the long term erosion that leads to deep denudation over geologic time. Mass movement in the Himalaya is scale-dependent, from the massive extension of whole mountain ranges (gravity tectonics), through the sackung failure of single peaks, to the smallest slope failures. Generally, denudation of the Himalayan orogen begins with slope failure onto glaciers and into river valleys and continues by glacial and fluvial transport. The maximum size of stable slopes and mean angles of slope that are produced by these failures are complex and controlled by a variety of factors, including mass strength of the rocks, stress fields, angles of internal friction controlled by rock type, cohesion that includes the control of rock temperature, bulk unit weight of rock, and discontinuities. The processes of mass movement in the Himalaya have been described many times for the past two centuries. Recently, developments in a variety of fields have been introduced to assess the character of mass movement. Geomorphometry, remote sensing, digital elevation models, and geographic information system technology are revolutionizing the study of mass movement in the Himalaya.

  12. Projected hydrologic changes in monsoon-dominated Himalaya Mountain basins with changing climate and deforestation

    Science.gov (United States)

    Neupane, Ram P.; White, Joseph D.; Alexander, Sara E.

    2015-06-01

    In mountain headwaters, climate and land use changes affect short and long term site water budgets with resultant impacts on landslide risk, hydropower generation, and sustainable agriculture. To project hydrologic change associated with climate and land use changes in the Himalaya Mountains, we used the Soil and Water Assessment Tool (SWAT) calibrated for the Tamor and Seti River basins located at eastern and western margins of Nepal. Future climate change was modeled using averaged temperature and precipitation for 2080 derived from Special Report on Emission Scenarios (SRES) (B1, A1B and A2) of 16 global circulation models (GCMs). Land use change was modeled spatially and included expansion of (1) agricultural land, (2) grassland, and (3) human settlement area that were produced by considering existing land use with projected changes associated with viability of elevation and slope characteristics of the basins capable of supporting different land use type. From these simulations, higher annual stream discharge was found for all GCM-derived scenarios compared to a baseline simulation with maximum increases of 13 and 8% in SRES-A2 and SRES-A1B for the Tamor and Seti basins, respectively. On seasonal basis, we assessed higher precipitation during monsoon season in all scenarios that corresponded with higher stream discharge of 72 and 68% for Tamor and Seti basins, respectively. This effect appears to be geographically important with higher influence in the eastern Tamor basin potentially due to longer and stronger monsoonal period of that region. However, we projected minimal changes in stream discharge for the land use scenarios potentially due to higher water transmission to groundwater reservoirs associated with fractures of the Himalaya Mountains rather than changes in surface runoff. However, when combined the effects of climate and land use changes, discharge was moderately increased indicating counteracting mechanisms of hydrologic yield in these mountains. Better understanding of potential hydrologic response to climate and land use changes in these basins might be crucial for national and transnational water management.

  13. Satellite Remote Sensing of Snow/Ice Albedo over the Himalayas

    Science.gov (United States)

    Hsu, N. Christina; Gautam, Ritesh

    2012-01-01

    The Himalayan glaciers and snowpacks play an important role in the hydrological cycle over Asia. The seasonal snow melt from the Himalayan glaciers and snowpacks is one of the key elements to the livelihood of the downstream densely populated regions of South Asia. During the pre-monsoon season (April-May-June), South Asia not only experiences the reversal of the regional meridional tropospheric temperature gradient (i.e., the onset of the summer monsoon), but also is being bombarded by dry westerly airmass that transports mineral dust from various Southwest Asian desert and arid regions into the Indo-Gangetic Plains in northern India. Mixed with heavy anthropogenic pollution, mineral dust constitutes the bulk of regional aerosol loading and forms an extensive and vertically extended brown haze lapping against the southern slopes of the Himalayas. Episodic dust plumes are advected over the Himalayas, and are discernible in satellite imagery, resulting in dust-capped snow surface. Motivated by the potential implications of accelerated snowmelt, we examine the changes in radiative energetics induced by aerosol transport over the Himalayan snow cover by utilizing space borne observations. Our objective lies in the investigation of potential impacts of aerosol solar absorption on the Top-of-Atmosphere (TOA) spectral reflectivity and the broadband albedo, and hence the accelerated snowmelt, particularly in the western Himalayas. Lambertian Equivalent Reflectivity (LER) in the visible and near-infrared wavelengths, derived from Moderate Resolution Imaging Spectroradiometer radiances, is used to generate statistics for determining perturbation caused due to dust layer over snow surface in over ten years of continuous observations. Case studies indicate significant reduction of LER ranging from 5 to 8% in the 412-860nm spectra. Broadband flux observations, from the Clouds and the Earth's Radiant Energy System, are also used to investigate changes in shortwave TOA flux over dust-laden and dust-free snow covered regions. Additionally, spatio-temporal and intra-seasonal variations of LER, along with snow cover information, are used to characterize the seasonal melt pattern and thus to distinguish the outstanding aerosol-induced snowmelt signal. Results from this observational work are expected to provide better understanding of the radiative impact of aerosols over snow surface, especially its role in the Himalayan hydro-glacialogical variability.

  14. FOREST ECOSYSTEM DYNAMICS ASSESSMENT AND PREDICTIVE MODELLING IN EASTERN HIMALAYA

    Directory of Open Access Journals (Sweden)

    S. P. S. Kushwaha

    2012-09-01

    Full Text Available This study focused on the forest ecosystem dynamics assessment and predictive modelling deforestation and forest cover prediction in a part of north-eastern India i.e. forest areas along West Bengal, Bhutan, Arunachal Pradesh and Assam border in Eastern Himalaya using temporal satellite imagery of 1975, 1990 and 2009 and predicted forest cover for the period 2028 using Cellular Automata Markov Modedel (CAMM. The exercise highlighted large-scale deforestation in the study area during 1975–1990 as well as 1990–2009 forest cover vectors. A net loss of 2,334.28 km2 forest cover was noticed between 1975 and 2009, and with current rate of deforestation, a forest area of 4,563.34 km2 will be lost by 2028. The annual rate of deforestation worked out to be 0.35 and 0.78% during 1975–1990 and 1990–2009 respectively. Bamboo forest increased by 24.98% between 1975 and 2009 due to opening up of the forests. Forests in Kokrajhar, Barpeta, Darrang, Sonitpur, and Dhemaji districts in Assam were noticed to be worst-affected while Lower Subansiri, West and East Siang, Dibang Valley, Lohit and Changlang in Arunachal Pradesh were severely affected. Among different forest types, the maximum loss was seen in case of sal forest (37.97% between 1975 and 2009 and is expected to deplete further to 60.39% by 2028. The tropical moist deciduous forest was the next category, which decreased from 5,208.11 km2 to 3,447.28 (33.81% during same period with further chances of depletion to 2,288.81 km2 (56.05% by 2028. It noted progressive loss of forests in the study area between 1975 and 2009 through 1990 and predicted that, unless checked, the area is in for further depletion of the invaluable climax forests in the region, especially sal and moist deciduous forests. The exercise demonstrated high potential of remote sensing and geographic information system for forest ecosystem dynamics assessment and the efficacy of CAMM to predict the forest cover change.

  15. EVALUATION OF ANTIMICROBIAL PROPERTIES OF TERRESTRIAL ORCHIDS (COLLECTED FROM NORTHERN HIMALAYAS AGAINST CERTAIN HUMAN PATHOGENS

    Directory of Open Access Journals (Sweden)

    Amit Bharal*, Manila Kashyap, Vipan Kumar Sohpal and Jaspreet Kaur Sembi

    2014-05-01

    Full Text Available The four main varieties of orchids, collected from northern Himalayas (Tara devi and Chhrabra forests, Shimla, HP were evaluated for their antimicrobial activity against human pathogenic bacteria. The ethanol and methanol extracts of Cypripedium cordigerum and Malaxis acuminata were found to be highly active against both P.aeruginosa and S.aureus with minimal microbial static concentration (MIC in the range of 100mg/ml. These plants particularly demonstrated antimicrobial properties against Gram negative bacterial strains, which are responsible for severe opportunistic bacterial infection and are resistant to hospitalized infections. These orchid species may thus, be considered important tools in antibacterial strategies. It can be concluded that orchid family represent an untapped source of potentially useful antibacterial products and are worthy of further study.

  16. Connecting source and transport: Suspended sediments in the Nepal Himalayas

    Science.gov (United States)

    Andermann, Christoff; Crave, Alain; Gloaguen, Richard; Davy, Philippe; Bonnet, Stéphane

    2012-10-01

    Understanding the dynamics of sediment fluxes is a key issue to constrain modern erosion rates in mountain belts and determine the still debated level of control exerted by precipitation, topography and tectonics. The well defined monsoon seasonality in the Himalayas, together with active tectonics and strong relief provide an ideal environment to assess these possible interactions. For this purpose, we present a new compilation of daily suspended sediment data for 12 stations of the major rivers of the Nepal Himalayas. We analyze the relationships of sediment transport with daily river discharge and precipitation data as well as with morphometric parameters. We show that suspended sediment concentrations vary systematically through the seasons and asynchronously to river discharge displaying a hysteresis effect. This clockwise hysteresis effect disappears when suspended sediment fluxes are directly compared with direct storm discharge. Therefore we attribute the hysteresis effect to groundwater dilution rather than a sediment supply limitation. We infer a rating model to calculate erosion rates directly from long river discharge chronicles. We show that, when normalized by drainage area and mean sediment flux, all rivers exhibit the same trend. This similarity implies that all river basins have the same erosion behavior, independent of location, size and catchment characteristics. Erosion rates calculated from suspended sediment fluxes range between 0.1 and 2.8 mm/yr. The erosion rates of the three main basins of Nepal are in the range 0.9-1.5 mm/yr, Erosion rates in the Higher Himalayas are relatively low (Kali Gandaki), while in the Lesser Himalayas they range from 0.2 to 2 mm/yr. We propose that material transport in the rivers depends on hillslope sediment supply, which is, in turn, controlled by those rainfalls producing direct runoff. In other words, the rivers in the Nepal Himalayas are supply-limited and the hillsopes as a contributing source are transport-limited. We also show that erosion processes are not as much controlled by infrequently occurring extreme precipitation events, than by moderate ones with a high recurrence interval.

  17. Geomorphological evidences of post-LGM glacial advancements in the Himalaya: A study from Chorabari Glacier, Garhwal Himalaya, India

    Indian Academy of Sciences (India)

    Manish Mehta; Zahid Majeed; D P Dobhal; Pradeep Srivastava

    2012-02-01

    Field geomorphology and remote sensing data, supported by Optical Stimulated Luminescence (OSL) dating from the Mandakini river valley of the Garhwal Himalaya enabled identification of four major glacial events; Rambara Glacial Stage (RGS) (13 ± 2 ka), Ghindurpani Glacial Stage (GhGS) (9 ± 1 ka), Garuriya Glacial Stage (GGS) (7 ± 1 ka) and Kedarnath Glacial Stage (KGS) (5 ± 1 ka). RGS was the most extensive glaciation extending for ∼6 km down the valley from the present day snout and lowered to an altitude of 2800 m asl at Rambara covering around ∼31 km2 area of the Mandakini river valley. Compared to this, the other three glaciations (viz., GhGS, GGS and KGS) were of lower magnitudes terminating around ∼3000, ∼3300 and ∼3500 m asl, respectively. It was also observed that the mean equilibrium line altitude (ELA) during RGS was lowered to 4747 m asl compared to the present level of 5120 m asl. This implies an ELA depression of ∼373 m during the RGS which would correspond to a lowering of ∼2°C summer temperature during the RGS. The results are comparable to that of the adjacent western and central Himalaya implying a common forcing factor that we attribute to the insolation-driven monsoon precipitation in the western and central Himalaya.

  18. Mining for diagnostic information in body surface potential maps: A comparison of feature selection techniques

    Directory of Open Access Journals (Sweden)

    McCullagh Paul J

    2005-09-01

    Full Text Available Abstract Background In body surface potential mapping, increased spatial sampling is used to allow more accurate detection of a cardiac abnormality. Although diagnostically superior to more conventional electrocardiographic techniques, the perceived complexity of the Body Surface Potential Map (BSPM acquisition process has prohibited its acceptance in clinical practice. For this reason there is an interest in striking a compromise between the minimum number of electrocardiographic recording sites required to sample the maximum electrocardiographic information. Methods In the current study, several techniques widely used in the domains of data mining and knowledge discovery have been employed to mine for diagnostic information in 192 lead BSPMs. In particular, the Single Variable Classifier (SVC based filter and Sequential Forward Selection (SFS based wrapper approaches to feature selection have been implemented and evaluated. Using a set of recordings from 116 subjects, the diagnostic ability of subsets of 3, 6, 9, 12, 24 and 32 electrocardiographic recording sites have been evaluated based on their ability to correctly asses the presence or absence of Myocardial Infarction (MI. Results It was observed that the wrapper approach, using sequential forward selection and a 5 nearest neighbour classifier, was capable of choosing a set of 24 recording sites that could correctly classify 82.8% of BSPMs. Although the filter method performed slightly less favourably, the performance was comparable with a classification accuracy of 79.3%. In addition, experiments were conducted to show how (a features chosen using the wrapper approach were specific to the classifier used in the selection model, and (b lead subsets chosen were not necessarily unique. Conclusion It was concluded that both the filter and wrapper approaches adopted were suitable for guiding the choice of recording sites useful for determining the presence of MI. It should be noted however that in this study recording sites have been suggested on their ability to detect disease and such sites may not be optimal for estimating body surface potential distributions.

  19. Polymers of 1-vinyl-2-pyrrolidinone as potential vitreous substitutes: physical selection.

    Science.gov (United States)

    Hong, Y; Chirila, T V; Cuypers, M J; Constable, I J

    1996-10-01

    More than 300 polymers of 1-vinyl-2-pyrrolidinone (VP) were synthesized, subjected to hydration, and characterized with the aim to select the most suitable materials as potential artificial substitutes for the vitreous body of the eye. The materials include cross-linked homopolymers, uncross-linked copolymers of VP with 2-hydroxyethyl methacrylate (HEMA), and cross-linked copolymers VP/HEMA. Five different cross-linking agents, both hydrophobic and hydrophilic, were used in this study. The resulting hydrogels, with equilibrium water contents ranging between 66.5 and 99.1%, were first subjected to a selection based on their physical behavior during manipulation, after which only the transparent, viscoelastic gels were further considered. Subsequent injectability and visual acuity tests, as well as the evaluation of light transmission characteristics, reduced further the number of potential candidates for vitreous substitution to only thirteen hydrogels. An eliminatory strategy based on physical properties of the potential vitreous substitutes is essential in order to avoid unnecessary sacrifice of experimental animals for in vivo assessment. PMID:8913849

  20. A comparative study on the potential of oxygen release by roots of selected wetland plants

    Science.gov (United States)

    Yao, Fang; Shen, Gen-xiang; Li, Xue-lian; Li, Huai-zheng; Hu, Hong; Ni, Wu-zhong

    The capacity of root oxygen release by selected wetland plants pre-grown under both nutrient solution and artificial wastewater conditions were determined. The results indicated that the significant differences of root oxygen release by the tested wetland plants existed, and the biochemical process was the main source of root oxygen release as oxygen released by Vetiveria zizanioides L. Nash roots through biochemical process was contributed to 77% and 74% of total root oxygen release under nutrient solution conditions and artificial wastewater conditions, respectively, and that was 72% and 71% of total root oxygen release for Cyperus alternifolius L. It was found that the formation of root plaque with iron oxide was a function of root oxygen release as iron oxide concentration in root plaque was positively correlated to the potential of oxygen released by wetland plant roots with the regression coefficients as 0.874 *( p artificial wastewater conditions, which could be regarded as an important mechanism of wetland plants being tolerant to anoxia during wastewater treatment. It was suggested that the potential of root oxygen release could be used as a parameter for selecting wetland plants that can increase oxygen supply to soil or substrate of constructed wetlands and enhance nutrient transformation and removal, and V. zizanioides L. Nash with the highest potential of root oxygen release and higher tolerance to wastewater could be recommended to establish vegetated wetlands for treating nutrient-rich wastewater such as domestic wastewater.

  1. Acoustic noise alters selective attention processes as indicated by direct current (DC) brain potential changes.

    Science.gov (United States)

    Trimmel, Karin; Schätzer, Julia; Trimmel, Michael

    2014-01-01

    Acoustic environmental noise, even of low to moderate intensity, is known to adversely affect information processing in animals and humans via attention mechanisms. In particular, facilitation and inhibition of information processing are basic functions of selective attention. Such mechanisms can be investigated by analyzing brain potentials under conditions of externally directed attention (intake of environmental information) versus internally directed attention (rejection of environmental stimuli and focusing on memory/planning processes). This study investigated brain direct current (DC) potential shifts-which are discussed to represent different states of cortical activation-of tasks that require intake and rejection of environmental information under noise. It was hypothesized that without background noise rejection tasks would show more positive DC potential changes compared to intake tasks and that under noise both kinds of tasks would show positive DC shifts as an expression of cortical inhibition caused by noise. DC potential shifts during intake and rejection tasks were analyzed at 16 standard locations in 45 persons during irrelevant speech or white noise vs. control condition. Without noise, rejection tasks were associated with more positive DC potential changes compared to intake tasks. During background noise, however, this difference disappeared and both kinds of tasks led to positive DC shifts. Results suggest-besides some limitations-that noise modulates selective attention mechanisms by switching to an environmental information processing and noise rejection mode, which could represent a suggested "attention shift". Implications for fMRI studies as well as for public health in learning and performance environments including susceptible persons are discussed. PMID:25264675

  2. Acoustic Noise Alters Selective Attention Processes as Indicated by Direct Current (DC Brain Potential Changes

    Directory of Open Access Journals (Sweden)

    Karin Trimmel

    2014-09-01

    Full Text Available Acoustic environmental noise, even of low to moderate intensity, is known to adversely affect information processing in animals and humans via attention mechanisms. In particular, facilitation and inhibition of information processing are basic functions of selective attention. Such mechanisms can be investigated by analyzing brain potentials under conditions of externally directed attention (intake of environmental information versus internally directed attention (rejection of environmental stimuli and focusing on memory/planning processes. This study investigated brain direct current (DC potential shifts—which are discussed to represent different states of cortical activation—of tasks that require intake and rejection of environmental information under noise. It was hypothesized that without background noise rejection tasks would show more positive DC potential changes compared to intake tasks and that under noise both kinds of tasks would show positive DC shifts as an expression of cortical inhibition caused by noise. DC potential shifts during intake and rejection tasks were analyzed at 16 standard locations in 45 persons during irrelevant speech or white noise vs. control condition. Without noise, rejection tasks were associated with more positive DC potential changes compared to intake tasks. During background noise, however, this difference disappeared and both kinds of tasks led to positive DC shifts. Results suggest—besides some limitations—that noise modulates selective attention mechanisms by switching to an environmental information processing and noise rejection mode, which could represent a suggested “attention shift”. Implications for fMRI studies as well as for public health in learning and performance environments including susceptible persons are discussed.

  3. Dynamics in the quantum/classical limit based on selective use of the quantum potential

    Energy Technology Data Exchange (ETDEWEB)

    Garashchuk, Sophya, E-mail: garashchuk@sc.edu; Dell’Angelo, David; Rassolov, Vitaly A. [Department of Chemistry and Biochemistry, University of South Carolina, Columbia, South Carolina 29208 (United States)

    2014-12-21

    A classical limit of quantum dynamics can be defined by compensation of the quantum potential in the time-dependent Schrödinger equation. The quantum potential is a non-local quantity, defined in the trajectory-based form of the Schrödinger equation, due to Madelung, de Broglie, and Bohm, which formally generates the quantum-mechanical features in dynamics. Selective inclusion of the quantum potential for the degrees of freedom deemed “quantum,” defines a hybrid quantum/classical dynamics, appropriate for molecular systems comprised of light and heavy nuclei. The wavefunction is associated with all of the nuclei, and the Ehrenfest, or mean-field, averaging of the force acting on the classical degrees of freedom, typical of the mixed quantum/classical methods, is avoided. The hybrid approach is used to examine evolution of light/heavy systems in the harmonic and double-well potentials, using conventional grid-based and approximate quantum-trajectory time propagation. The approximate quantum force is defined on spatial domains, which removes unphysical coupling of the wavefunction fragments corresponding to distinct classical channels or configurations. The quantum potential, associated with the quantum particle, generates forces acting on both quantum and classical particles to describe the backreaction.

  4. Dynamics in the quantum/classical limit based on selective use of the quantum potential

    International Nuclear Information System (INIS)

    A classical limit of quantum dynamics can be defined by compensation of the quantum potential in the time-dependent Schrödinger equation. The quantum potential is a non-local quantity, defined in the trajectory-based form of the Schrödinger equation, due to Madelung, de Broglie, and Bohm, which formally generates the quantum-mechanical features in dynamics. Selective inclusion of the quantum potential for the degrees of freedom deemed “quantum,” defines a hybrid quantum/classical dynamics, appropriate for molecular systems comprised of light and heavy nuclei. The wavefunction is associated with all of the nuclei, and the Ehrenfest, or mean-field, averaging of the force acting on the classical degrees of freedom, typical of the mixed quantum/classical methods, is avoided. The hybrid approach is used to examine evolution of light/heavy systems in the harmonic and double-well potentials, using conventional grid-based and approximate quantum-trajectory time propagation. The approximate quantum force is defined on spatial domains, which removes unphysical coupling of the wavefunction fragments corresponding to distinct classical channels or configurations. The quantum potential, associated with the quantum particle, generates forces acting on both quantum and classical particles to describe the backreaction

  5. Second generation bioethanol potential from selected Malaysia's biodiversity biomasses: A review.

    Science.gov (United States)

    Aditiya, H B; Chong, W T; Mahlia, T M I; Sebayang, A H; Berawi, M A; Nur, Hadi

    2016-01-01

    Rising global temperature, worsening air quality and drastic declining of fossil fuel reserve are the inevitable phenomena from the disorganized energy management. Bioethanol is believed to clear out the effects as being an energy-derivable product sourced from renewable organic sources. Second generation bioethanol interests many researches from its unique source of inedible biomass, and this paper presents the potential of several selected biomasses from Malaysia case. As one of countries with rich biodiversity, Malaysia holds enormous potential in second generation bioethanol production from its various agricultural and forestry biomasses, which are the source of lignocellulosic and starch compounds. This paper reviews potentials of biomasses and potential ethanol yield from oil palm, paddy (rice), pineapple, banana and durian, as the common agricultural waste in the country but uncommon to be served as bioethanol feedstock, by calculating the theoretical conversion of cellulose, hemicellulose and starch components of the biomasses into bioethanol. Moreover, the potential of the biomasses as feedstock are discussed based on several reported works. PMID:26253329

  6. Facilitating the selection and creation of accurate interatomic potentials with robust tools and characterization

    Science.gov (United States)

    Trautt, Zachary T.; Tavazza, Francesca; Becker, Chandler A.

    2015-10-01

    The Materials Genome Initiative seeks to significantly decrease the cost and time of development and integration of new materials. Within the domain of atomistic simulations, several roadblocks stand in the way of reaching this goal. While the NIST Interatomic Potentials Repository hosts numerous interatomic potentials (force fields), researchers cannot immediately determine the best choice(s) for their use case. Researchers developing new potentials, specifically those in restricted environments, lack a comprehensive portfolio of efficient tools capable of calculating and archiving the properties of their potentials. This paper elucidates one solution to these problems, which uses Python-based scripts that are suitable for rapid property evaluation and human knowledge transfer. Calculation results are visible on the repository website, which reduces the time required to select an interatomic potential for a specific use case. Furthermore, property evaluation scripts are being integrated with modern platforms to improve discoverability and access of materials property data. To demonstrate these scripts and features, we will discuss the automation of stacking fault energy calculations and their application to additional elements. While the calculation methodology was developed previously, we are using it here as a case study in simulation automation and property calculations. We demonstrate how the use of Python scripts allows for rapid calculation in a more easily managed way where the calculations can be modified, and the results presented in user-friendly and concise ways. Additionally, the methods can be incorporated into other efforts, such as openKIM.

  7. Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies.

    Science.gov (United States)

    Penna-Coutinho, Julia; Cortopassi, Wilian Augusto; Oliveira, Aline Alves; França, Tanos Celmar Costa; Krettli, Antoniana Ursine

    2011-01-01

    The Plasmodium falciparum lactate dehydrogenase enzyme (PfLDH) has been considered as a potential molecular target for antimalarials due to this parasite's dependence on glycolysis for energy production. Because the LDH enzymes found in P. vivax, P. malariae and P. ovale (pLDH) all exhibit ?90% identity to PfLDH, it would be desirable to have new anti-pLDH drugs, particularly ones that are effective against P. falciparum, the most virulent species of human malaria. Our present work used docking studies to select potential inhibitors of pLDH, which were then tested for antimalarial activity against P. falciparum in vitro and P. berghei malaria in mice. A virtual screening in DrugBank for analogs of NADH (an essential cofactor to pLDH) and computational studies were undertaken, and the potential binding of the selected compounds to the PfLDH active site was analyzed using Molegro Virtual Docker software. Fifty compounds were selected based on their similarity to NADH. The compounds with the best binding energies (itraconazole, atorvastatin and posaconazole) were tested against P. falciparum chloroquine-resistant blood parasites. All three compounds proved to be active in two immunoenzymatic assays performed in parallel using monoclonals specific to PfLDH or a histidine rich protein (HRP2). The IC(50) values for each drug in both tests were similar, were lowest for posaconazole (<5 µM) and were 40- and 100-fold less active than chloroquine. The compounds reduced P. berghei parasitemia in treated mice, in comparison to untreated controls; itraconazole was the least active compound. The results of these activity trials confirmed that molecular docking studies are an important strategy for discovering new antimalarial drugs. This approach is more practical and less expensive than discovering novel compounds that require studies on human toxicology, since these compounds are already commercially available and thus approved for human use. PMID:21779323

  8. Selection of phosphorus solubilizing bacteria with biocontrol potential for growth in phosphorus rich animal bone charcoal

    OpenAIRE

    Postma, J.; Nijhuis, E.H.; Sommeus, E.

    2010-01-01

    Bacteria with the ability to solubilize phosphorus (P) and to improve plant health were selected and tested for growth and survival in P-rich animal bone charcoal (ABC). ABC is suggested to be suitable as a carrier for biocontrol agents, offering them a protected niche as well as delivering phosphate to plants, meanwhile re-using P from waste of the food chain. Ninety-seven bacterial isolates from different soils were tested for their potential to dissolve P from ABC. Of these isolates, 60% s...

  9. Identification of Highly Potent and Selective ?-Glucosidase Inhibitors with Antiglycation Potential, Isolated from Rhododendron arboreum

    Directory of Open Access Journals (Sweden)

    Rabia Raza

    2015-01-01

    Full Text Available This study explored antidiabetic potential of eight known pure compounds, isolated from the bark of Rhododendron arboreum. Invitro studies of these compounds against ? and ?-glucosidases revealed them as very potent and selective inhibitors of ?-glucosidase. Compound 7 (3-O-acetylursolic acid was found to be the most potent inhibitor of ?-glucosidase with 3.3±0.1µM IC 50 value which was many folds higher than standard inhibitor acarbose. Antiglycation studies of compounds showed that all compounds were also very active antiglycation agents. The studied biological properties of these compounds suggest that they are therapeutically interesting and important tools for treatment of diabetes.

  10. Artificial hyperglycemia as a factor potentiating selectively an anti-tumoral radiation effect

    International Nuclear Information System (INIS)

    An important peculiarity of tumoral cells is their ability for intensive glycolysis. Potential biochemical mechanisms of this phenomenon are considered in the review. A tumoral process is closely connected with the changes in glucose metabolism in an organism. Therefore artificial hyperglycemia (AH) can be an instrument for intervention into tumoral cell energetics. Many experimental data show an increase of glucose consumption at AH. Long-term AH causes a reduction of tumor pH. Various view points on AH antitumoral effect mechanism are considered. Data on changes in a sound organism in case of long-term AH are given. It has been found that AH does not cause irreversible changes on the part of organs and systems of the organism. Experimental data on a possibility of using short-term hyperglycemia as a factor selectively potentiating antitumoral radiation effect are considered

  11. Framing hydropower as green energy: assessing drivers, risks and tensions in the Eastern Himalayas

    Science.gov (United States)

    Ahlers, R.; Budds, J.; Joshi, D.; Merme, V.; Zwarteveen, M.

    2015-04-01

    The culturally and ecologically diverse region of the Eastern Himalayas is the target of ambitious hydropower development plans. Policy discourses at national and international levels position this development as synergistically positive: it combines the production of clean energy to fuel economic growth at regional and national levels with initiatives to lift poor mountain communities out of poverty. Different from hydropower development in the 20th century in which development agencies and banks were important players, contemporary initiatives importantly rely on the involvement of private actors, with a prominent role of the private finance sector. This implies that hydropower development is not only financially viable but also understood as highly profitable. This paper examines the new development of hydropower in the Eastern Himalayas of Nepal and India. It questions its framing as green energy, interrogates its links with climate change, and examines its potential for investment and capital accumulation. To do this, we also review the evidence on the extent to which its construction and operation may modify existing hydrogeological processes and ecosystems, as well as its impacts on the livelihoods of diverse groups of people that depend on these. The paper concludes that hydropower development in the region is characterized by inherent contentions and uncertainties, refuting the idea that dams constitute development projects whose impacts can be simply predicted, controlled and mitigated. Indeed, in a highly complex geological, ecological, cultural and political context that is widely regarded to be especially vulnerable to the effects of climate change, hydropower as a development strategy makes for a toxic cocktail.

  12. Framing hydropower as green energy: assessing drivers, risks and tensions in the Eastern Himalayas

    Directory of Open Access Journals (Sweden)

    R. Ahlers

    2014-11-01

    Full Text Available The culturally and ecologically diverse region of the Eastern Himalayas is the target of ambitious hydropower development plans. Policy discourses at national and international levels position this development as synergistically positive: it combines the production of clean energy to fuel economic growth at regional and national levels with initiatives to lift poor mountain communities out of poverty. Different from hydropower development in the 20th century in which development agencies and banks were important players, contemporary initiatives importantly rely on the involvement of private actors, with a prominent role of the private finance sector. This implies that hydropower development is not only financially viable but also understood as highly profitable. This paper examines the new development of hydropower in the Eastern Himalaya of Nepal and India. It questions its framing as green energy, interrogates its links with climate change, and examines its potential for investment and capital accumulation. To do this, we also review the evidence on the extent to which its construction and operation may modify existing hydrogeological processes and ecosystems, as well as its impacts on the livelihoods of diverse groups of people that depend on these. The paper concludes that hydropower development in the region is characterised by inherent contentions and uncertainties, refuting the idea that dams constitute development projects whose impacts can be simply predicted, controlled and mitigated. Indeed, in a highly complex geological, ecological, cultural and political context that is widely regarded to be especially vulnerable to the effects of climate change, hydropower as a development strategy makes for a toxic cocktail.

  13. Altitudinal variation of soil organic carbon stocks in temperate forests of Kashmir Himalayas, India.

    Science.gov (United States)

    Ahmad Dar, Javid; Somaiah, Sundarapandian

    2015-02-01

    Soil organic carbon stocks were measured at three depths (0-10, 10-20, and 20-30 cm) in seven altitudes dominated by different forest types viz. Populus deltoides, 1550-1800 m; Juglans regia, 1800-2000 m; Cedrus deodara, 2050-2300 m; Pinus wallichiana, 2000-2300 m; mixed type, 2200-2400 m; Abies pindrow, 2300-2800 m; and Betula utilis, 2800-3200 m in temperate mountains of Kashmir Himalayas. The mean range of soil organic carbon (SOC) stocks varied from 39.07 to 91.39 Mg C ha(-1) in J. regia and B. utilis forests at 0-30 cm depth, respectively. Among the forest types, the lowest mean range of SOC at three depths (0-10, 10-20, and 20-30 cm) was observed in J. regia (18.55, 11.31, and 8.91 Mg C ha(-1), respectively) forest type, and the highest was observed in B. utilis (54.10, 21.68, and 15.60 Mg C ha(-1), respectively) forest type. SOC stocks showed significantly (R (2)?=?0.67, P?=?0.001) an increasing trend with increase in altitude. On average, the percentages of SOC at 0-10-, 10-20-, and 20-30-cm depths were 53.2, 26.5, and 20.3 %, respectively. Bulk density increased significantly with increase in soil depth and decreased with increase in altitude. Our results suggest that SOC stocks in temperate forests of Kashmir Himalaya vary greatly with forest type and altitude. The present study reveals that SOC stocks increased with increase in altitude at high mountainous regions. Climate change in these high mountainous regions will alter the carbon sequestration potential, which would affect the global carbon cycle. PMID:25619695

  14. Decoupling of long-term exhumation and short-term erosion rates in the Sikkim Himalaya

    Science.gov (United States)

    Abrahami, Rachel; van der Beek, Peter; Huyghe, Pascale; Hardwick, Elisabeth; Carcaillet, Julien

    2016-01-01

    Understanding the relative strengths of tectonic and climatic forcing on erosion at different spatial and temporal scales is important to understand the evolution of orogenic topography. To address this question, we quantified exhumation rates at geological timescales and erosion rates at millennial timescales in modern river sands from 10 sub-catchments of the Tista River drainage basin in the Sikkim Himalaya (northeast India) using detrital apatite fission-track thermochronology and cosmogenic 10Be analyses, respectively. We compare these rates to several potential geomorphic or climatic forcing parameters. Our results show that millennial erosion rates are generally higher and spatially more variable than long-term exhumation rates in Sikkim. They also show strongly contrasting spatial patterns, suggesting that the processes controlling these rates are decoupled. At geological timescales, exhumation rates decrease from south to north, with rates up to 1.2 ± 0.6 mm/yr recorded in southwest Sikkim and as low as 0.5 ± 0.2 mm/yr in the northernmost catchment. Long-term exhumation rates do not correlate with any geomorphic or climatic parameter. We suggest they are tectonically controlled: high rates in southwest Sikkim may be linked to the building of the Lesser Himalaya Rangit Duplex, whereas low rates in north Sikkim are consistent with cessation of extensional exhumation along the South Tibetan Detachment after 13 Ma. The highest apparent erosion rates recorded by cosmogenic nuclides (˜5 mm/yr) occur in catchments spanning the Main Central Thrust Zone, but these appear to be strongly influenced by recent landsliding. High millennial erosion rates (1-2 mm/yr) also occur in north Sikkim and may be climatically driven through strong glacial inheritance of the landscape, as attested by high channel-steepness values close to the maximum extent of glaciers during the Last Glacial Maximum. In contrast, variations in rainfall rate do not seem to strongly influence either millennial erosion or long-term exhumation rates in Sikkim.

  15. ABCG2 is a selectable marker for enhanced multilineage differentiation potential in periodontal ligament stem cells.

    Science.gov (United States)

    Szepesi, Áron; Matula, Zsolt; Szigeti, Anna; Várady, György; Szabó, Gyula; Uher, Ferenc; Sarkadi, Balázs; Német, Katalin

    2015-01-15

    Periodontal ligament stem cells (PDLSCs) provide an important source for tissue regeneration and may become especially useful in the formation of osteogenic seeds. PDLSCs can be cultured, expanded, and differentiated in vitro; thus, they may be applied in the long-term treatment of the defects in the dental regions. Here we studied numerous potential markers allowing the selection of human PDLSCs with a maximum differentiation potential. We followed the expression of the ATP-binding cassette subfamily G member 2 (ABCG2) membrane transporter protein and isolated ABCG2-expressing cells by using a monoclonal antibody, recognizing the transporter at the cell surface in intact cells. The expression of the ABCG2 protein, corresponding to the so-called side-population phenotype in various tissue-derived stem cells, was found to be a useful marker for the selection of PDLSCs with enhanced osteogenic, chondrogenic, and adipogenic differentiation. These findings may have important applications in achieving efficient dental tissue regeneration by using stem cells from extracted teeth. PMID:25101689

  16. Winter wheat hull (husk) is a valuable source for tricin, a potential selective cytotoxic agent.

    Science.gov (United States)

    Moheb, Amira; Grondin, Melanie; Ibrahim, Ragai K; Roy, René; Sarhan, Fathey

    2013-06-01

    The flavone, tricin (5,7,4'-trihydroxy-3',5'-dimethoxyflavone) has great potential as an anticancer agent, due to its specific chemopreventive activity. In spite of these characteristics, its use in preclinical studies is still limited, mainly because of its limited availability and high production cost. Tricin is found mainly in cereal grains, such as wheat, rice, barley, oat and maize. However, its concentration in these plants is not sufficient for commercial use. To find a reliable, rich source of tricin, we investigated its distribution in different parts of wheat (Triticum aestivum) and designed an efficient method for its isolation and purification. The highest amount (770 ± 157 mg/kg dry weight) was found in the husks of winter wheat. This concentration is one of the highest in any plant species and is considered as a cheap source of natural tricin. The purified wheat husks tricin was found to be a selective potent inhibitor of two cancer cell lines of liver and pancreas, while having no side effects on normal cells. This selective action suggests that tricin could be considered as a potential candidate for pre-clinical trials as a chemopreventive agent. In addition, fibre-rich crude wheat husk could be used as a natural chemopreventive agent in food supplement. PMID:23411198

  17. The Limits of Extrusion in the Western Himalaya

    Science.gov (United States)

    Zhang, K.; Webb, A. G.; Donaldson, D.; Johnson, S.; Elorriaga, T.

    2014-12-01

    Himalayan orogenesis is commonly explained by 1) extrusion models, involving expulsion of high-grade rocks southwards from beneath Tibet and up towards the High Himalayan orographic front, and/or 2) duplexing models, involving accretion of thrust horses from the downgoing Indian plate to the over-riding orogenic wedge. Most extrusion models predict exhumation and erosion of upper-amphibolite facies metamorphic rocks between the Main Central thrust (MCT) and a structurally higher normal fault, and therefore can be tested by determining if such high grade rocks occur between the MCT and the Indus-Yalu suture to the north. Prior qualitative studies suggest that such rocks are missing across the east Ladakh / Chamba and Kashmir regions of the western Himalaya. Here we present new quantitative and semi-quantitative results that document low peak metamorphic temperatures along a northeast-trending transect across the east Ladakh / Chamba Himalaya. We performed illite crystallinity (IC) and quartz grain boundary analyses to determine metamorphic and deformation temperatures, respectively. Calibrated IC values of structurally high samples range from 0.25 to 0.54, indicating temperatures of ~100 ?C to ~300 ?C. In structurally lower, muscovite +/- biotite-bearing meta-pelitic and meta-psammitic rocks, quartz grain boundaries show bulging recrystallization fabrics, corresponding to deformation temperatures of <~450 ?C. Local exceptions occur along the southeast margin of the study region near a dome, where quartz sub-grain rotation fabrics indicate deformation temperatures between ~450 ?C and ~550 ?C. Our results, combined with similar IC values to the north from Girard et al. [2001, Clay Minerals v. 36, p. 237-247], demonstrate that a continuous strip of <~450 ?C rocks extends from the MCT to the Indus-Yalu suture here. Therefore the predictions of extrusion models are not met in this portion of the Himalaya; we present alternative duplexing models.

  18. Precipitation in the Karakoram-Himalaya: a CMIP5 view

    Science.gov (United States)

    Palazzi, Elisa; von Hardenberg, Jost; Terzago, Silvia; Provenzale, Antonello

    2015-07-01

    This work analyzes the properties of precipitation in the Hindu-Kush Karakoram Himalaya region as simulated by thirty-two state-of-the-art global climate models participating in the Coupled Model Intercomparison Project phase 5 (CMIP5). We separately consider the Hindu-Kush Karakoram (HKK) in the west and the Himalaya in the east. These two regions are characterized by different precipitation climatologies, which are associated with different circulation patterns. Historical model simulations are compared with the Climate Research Unit (CRU) and Global Precipitation Climatology Centre (GPCC) precipitation data in the period 1901-2005. Future precipitation is analyzed for the two representative concentration pathways (RCP) RCP 4.5 and RCP 8.5 scenarios. We find that the multi-model ensemble mean and most individual models exhibit a wet bias with respect to CRU and GPCC observations in both regions and for all seasons. The models differ greatly in the seasonal climatology of precipitation which they reproduce in the HKK. The CMIP5 models predict wetter future conditions in the Himalaya in summer, with a gradual precipitation increase throughout the 21st century. Wetter summer future conditions are also predicted by most models in the RCP 8.5 scenario for the HKK, while on average no significant change can be detected in winter precipitation for both regions. In general, no single model (or group of models) emerges as that providing the best results for all the statistics considered, and the large spread in the behavior of individual models suggests to consider multi-model ensemble means with extreme care.

  19. The crustal structure of the western Himalayas and Tibet

    Science.gov (United States)

    Gilligan, Amy; Priestley, Keith F.; Roecker, Steven W.; Levin, Vadim; Rai, S. S.

    2015-05-01

    We present new, high-resolution, shear velocity models for the western Himalayas and West Tibet from the joint inversion of P receiver functions recorded using seismic stations from four arrays in this region and fundamental mode Rayleigh wave group velocity maps from 5-70 s covering Central and Southern Asia. The Tibetan Plateau is a key locality in understanding large-scale continental dynamics. A large number of investigations has examined the structure and processes in eastern Tibet; however, western Tibet remains relatively understudied. Previous studies in this region indicate that the western part of the Tibetan Plateau is not a simple extension of the eastern part. The areas covered by these arrays include the Karakoram and Altan-Tagh faults, and major terrane boundaries in West Tibet and the Himalayas. The arrays used include broadband data collected by the West Tibet Array, a U.S.-China deployment on the western side of the Tibetan Plateau between 2007 and 2011. We use the shear wave velocity models to obtain estimates of Moho depth. The Moho is deep (68-84 km) throughout West Tibet. We do not observe significant steps within the Moho beneath West Tibet. A large step in Moho depth is observed at the Altyn-Tagh fault, where Moho depths are 20-30 km shallower to the north of the fault compared to those to the south. Beneath the Lhasa Terrane and Tethyan Himalayas, we observe a low-velocity zone in the midcrust. This feature is not interrupted by the Karakoram Fault, suggesting that the Karakoram Fault does not cut through the entire crust.

  20. Interannual Variability of Snow Water Equivalent (SWE) over Western Himalayas

    Science.gov (United States)

    Tiwari, Sarita; Kar, Sarat C.; Bhatla, R.

    2015-08-01

    Considering the importance of snow and glaciers in the Himalayas for understanding the water cycle and for water resource management of the rivers originating from the Himalayan, interannual variability of snow accumulation process over Himalayas and surrounding region has been studied using snow water equivalent (SWE) data. Remote sensing data from National Snow and Ice Data Centre have been used. These data have been compared against ground (in situ) observations of SWE measured at several gauge stations in the Indian part of the Satluj River basin. Accumulated SWE from remote sensing data and ground observations in the Satluj River basin have good and significant correlation. These data have also been compared against the Climate Forecast System Reanalysis and the European Centre for Medium Range Weather Forecast reanalysis-Interim (ERA-I). Upper air and surface data from the reanalyses have also been used to examine the atmospheric conditions when snowfall occurs and snow accumulates for the season. In this study, it is found that there is large interannual variation in SWE over western Himalayas and Satluj River basin (domain of interest). During excess years of snowfall, strong westerly winds are observed at 500 hPa over India. In wind anomaly, a cyclonic circulation is seen over northern parts of India with a deep trough along Pakistan, Rajasthan and Gujarat region. As a consequence of this trough, a moisture convergence zone is established in the region leading to more amount of snowfall. At the same time, during excess snow accumulation years, the air temperature from the surface to 500 hPa is colder than other years enabling the fallen snow to accumulate through the season.

  1. Phenotypic variation and water selection potential in the stem structure of invasive alligator weed

    Science.gov (United States)

    Du, Leshan; Yang, Beifen; Guan, Wenbin; Li, Junmin

    2016-02-01

    The morphological and anatomical characteristics of stems have been found to be related to drought resistance in plants. Testing the phenotypic selection of water availability on stem anatomical traits would be useful for exploring the evolutionary potential of the stem in response to water availability. To test the phenotypic variation of the stem anatomical traits of an invasive plant in response to water availability, we collected a total of 320 individuals of Alternanthera philoxeroides from 16 populations from terrestrial and aquatic habitats in 8 plots in China and then analyzed the variation, differentiation, plasticity and selection potential of water availability on the stem anatomical traits. We found that except for the thickness of the cortex, all of the examined phenotypic parameters of the A. philoxeroides stem were significantly and positively correlated with soil water availability. The phenotypic differentiation coefficient for all of the anatomical structural parameters indicated that most of the variation existed between habitats within the same plot, whereas there was little variation among plots or among individuals within the same habitat except for variation in the thickness of the cortex. A significant phenotypic plasticity response to water availability was found for all of the anatomical traits of A. philoxeroides stem except for the thickness of the cortex. The associations between fitness and some of the anatomical traits, such as the stem diameter, the cortex area-to-stem area ratio, the pith cavity area-to-stem area ratio and the density of vascular bundles, differed with heterogeneous water availability. In both the aquatic and terrestrial habitats, no significant directional selection gradient was found for the stem diameter, the cortex area-to-stem area ratio or the density of vascular bundles. These results indicated that the anatomical structure of the A. philoxeroides stem may play an important role in the adaptation to changes in water availability.

  2. The Large-Bodied hominoids of the Himalayas

    Directory of Open Access Journals (Sweden)

    Michael Trachtengerts

    2012-11-01

    Full Text Available The review of available data concerning to large-bodied hominoids detected in the Himalayas is presented. They are mainly footprints (photographs by E.Shipton and M.Ward, P.Bordet, F.Smythe, and A.Woodridge and also narration of one remote observation. It is shown that on the whole these data reveal basic features of the undefined creature, most probably humanlike primate, and allow describing it as a separate species. One of its features is unusual four-toed foot with two strong toes and two small toes. A taxonomic name for this hominoid is proposed ¾ Homo pardigitatus sp. nov. ("That has paired toes".

  3. Genetic parameters for predicted methane production and potential for reducing enteric emissions through genomic selection.

    Science.gov (United States)

    Haas, Y de; Windig, J J; Calus, M P L; Dijkstra, J; Haan, M de; Bannink, A; Veerkamp, R F

    2011-12-01

    Mitigation of enteric methane (CH?) emission in ruminants has become an important area of research because accumulation of CH? is linked to global warming. Nutritional and microbial opportunities to reduce CH? emissions have been extensively researched, but little is known about using natural variation to breed animals with lower CH? yield. Measuring CH? emission rates directly from animals is difficult and hinders direct selection on reduced CH? emission. However, improvements can be made through selection on associated traits (e.g., residual feed intake, RFI) or through selection on CH? predicted from feed intake and diet composition. The objective was to establish phenotypic and genetic variation in predicted CH? output, and to determine the potential of genetics to reduce methane emissions in dairy cattle. Experimental data were used and records on daily feed intake, weekly body weights, and weekly milk production were available from 548 heifers. Residual feed intake (MJ/d) is the difference between net energy intake and calculated net energy requirements for maintenance as a function of body weight and for fat- and protein-corrected milk production. Predicted methane emission (PME; g/d) is 6% of gross energy intake (Intergovernmental Panel on Climate Change methodology) corrected for energy content of methane (55.65 kJ/g). The estimated heritabilities for PME and RFI were 0.35 and 0.40, respectively. The positive genetic correlation between RFI and PME indicated that cows with lower RFI have lower PME (estimates ranging from 0.18 to 0.84). Hence, it is possible to decrease the methane production of a cow by selecting more-efficient cows, and the genetic variation suggests that reductions in the order of 11 to 26% in 10 yr are theoretically possible, and could be even higher in a genomic selection program. However, several uncertainties are discussed; for example, the lack of true methane measurements (and the key assumption that methane produced per unit feed is not affected by RFI level), as well as the limitations of predicting the biological consequences of selection. To overcome these limitations, an international effort is required to bring together data on feed intake and methane emissions of dairy cows. PMID:22118100

  4. Attenuation Characteristics of Body-Waves for the Bilaspur Region of Himachal Lesser Himalaya

    Science.gov (United States)

    Vandana; Kumar, Ashwani; Gupta, S. C.

    2015-06-01

    The attenuation characteristics around Bilaspur region of the Himachal Lesser Himalaya have been estimated adopting extended-coda-normalization method, and using a data set of 41 local events (0.5 < M L ? 2.9) that occurred in the region from May 2013 to March 2014. The frequency-dependent relations governing the quality factors of P-waves (Q ? ) and S-waves (Q ? ) in the frequency range from 1.5 to 24 Hz are: (Q ? ) = (43 ± 4) f 1.30±0.04 and Q ? = (79 ± 6) f 1.25±0.02. The average estimates of (Q ? ) and (Q ? ) are found to vary from 71 and 125 at 1.5 Hz to 2901 and 4243 at 24 Hz, respectively. The (Q ? ) and (Q ? ) estimates are compared to the similar estimates obtained for the other seismically active regions of the Himalaya. It is found that for the various Himalayan regions, the (Q ? ) estimates at 1 Hz vary between 22 (for the Kumaon Himalaya) and 97 (for the northwest Himalaya), whereas (Q ? ) estimates range between 63 (for the Garhwal Himalaya) and 127 (for the northwest Himalaya). For the Bilaspur region, the (Q ? )/(Q ? ) ratio is greater than unity and varies between 1.84 and 1.45 in the frequency range from 1 to 24 Hz. The region-specific attenuation relations can be adopted for estimating earthquake source parameters, simulating strong ground motion and assessing seismic hazard for the Bilaspur region of Himachal Lesser Himalaya.

  5. Function-selective domain architecture plasticity potentials in eukaryotic genome evolution.

    Science.gov (United States)

    Linkeviciute, Viktorija; Rackham, Owen J L; Gough, Julian; Oates, Matt E; Fang, Hai

    2015-12-01

    To help evaluate how protein function impacts on genome evolution, we introduce a new concept of 'architecture plasticity potential' - the capacity to form distinct domain architectures - both for an individual domain, or more generally for a set of domains grouped by shared function. We devise a scoring metric to measure the plasticity potential for these domain sets, and evaluate how function has changed over time for different species. Applying this metric to a phylogenetic tree of eukaryotic genomes, we find that the involvement of each function is not random but highly selective. For certain lineages there is strong bias for evolution to involve domains related to certain functions. In general eukaryotic genomes, particularly animals, expand complex functional activities such as signalling and regulation, but at the cost of reducing metabolic processes. We also observe differential evolution of transcriptional regulation and a unique evolutionary role of channel regulators; crucially this is only observable in terms of the architecture plasticity potential. Our findings provide a new layer of information to understand the significance of function in eukaryotic genome evolution. A web search tool, available at http://supfam.org/Pevo, offers a wide spectrum of options for exploring functional importance in eukaryotic genome evolution. PMID:25980317

  6. Phenological attributes of Angelica glauca and A. archangelica expressed at two different climatic zones in Western Himalaya

    Directory of Open Access Journals (Sweden)

    Rajiv K. Vashistha

    2010-01-01

    Full Text Available Angelica glauca Edgew. and A. archangelica Linn., are high value medicinal and aromatic plants of the Himalaya. The present study examined phenological attributes of these species under cultivation at two different climatic zones in Western Himalaya, Uttarakhand, India. Plants of both species were cultivated in Tungnath (TN, an alpine zone (3600 m asl and in Pothivasa (PV, a temperate zone (2200 m asl. The results showed that the commencement and completion periods of phenophases, viz., growth initiation, vegetative phase, flowering, fruiting and senescence in both species varied greatly between the climatic zones. However, this variation was negligible between the species. It indicates that there is a need to develop location specific strategy for cultivation and management of the selected species. Further, the information will be highly helpful in determining appropriate time of cultivation practices, viz., seed sowing to harvesting of these species. Based on the corresponding life cycle of these species, it was also concluded that both the species can be cultivated in similar climatic conditions. Overall, the study will help in understanding adaptation features and planning strategies for successful cultivation and effective conservation management of these species.

  7. Implications of recent levelling observations for Tehri and other high dams in the Himalaya

    International Nuclear Information System (INIS)

    Seismic hazards around the Tehri and other existing and proposed high dams in the Himalaya are a matter of concern to many people. The magnitude and dimensions of the problem appear to increase with every new set of geophysical and geological data gathered from the Himalaya. But the flexibility and readiness of the people involved to improve their designs for the dams transparently in the light of the evolving perceptions about seismic hazards is not evident to us at least. In this article the evidence for an aspect of seismic hazards in the Himalaya is buttressed. (author). 44 refs., 3 figs

  8. Potential of Radiotelescopes for Atmospheric Line Observations: I. Observation Principles and Transmission Curves for Selected Sites

    CERN Document Server

    Schneider, Nicola; Baron, Philippe

    2009-01-01

    Existing and planned radiotelescopes working in the millimetre (mm) and sub-millimetre wavelengths range provide the possibility to be used for atmospheric line observations. To scrutinize this potential, we outline the differences and similarities in technical equipment and observing techniques between ground-based aeronomy mm-wave radiometers and radiotelescopes. Comprehensive tables summarizing the technical characteristics of existing and future (sub)-mm radiotelescopes are given. The advantages and disadvantages using radiotelescopes for atmospheric line observations are discussed. In view of the importance of exploring the sub-mm and far-infrared wavelengths range for astronomical observations and atmospheric sciences, we present model calculations of the atmospheric transmission for selected telescope sites (DOME-C/Antarctica, ALMA/Chajnantor, JCMT and CSO on Mauna Kea/Hawaii, KOSMA/Swiss Alpes) for frequencies between 0 and 2000 GHz (0 to 150 micron) and typical atmospheric conditions using the forwar...

  9. Growth and Yield Potential of Nine Selected Genotypes of Sweet Potato

    Directory of Open Access Journals (Sweden)

    M. J. Islam

    2002-01-01

    Full Text Available The growth and yield potential of nine selected genotypes of sweet potato was studied. Length and weight of vines per plant, number of main stems per plant, number and weight of tubers per plant and weight, length, diameter and dry matter content of tuber varied significantly among the genotypes. The genotypes SP3 gave the highest yield 47.59 t ha -1 followed by SP4 (42.82 t ha -1, SP16 (36.15 t ha -1 and SP1 (35.89 t ha -1. Tuber yield had significant and positive correlation with length and weight of vines per plant, number and weight of tubers per plant, average weight of tuber and diameter of tuber. Considering the associations into direct and indirect effects, weight of tubers per plant followed by average weight of tuber and number of tubers per plant found to contribute to the higher yield.

  10. Selective uptake of porphyrins within experimental atheromatous plaques: Potential for laser photodynamic therapy

    International Nuclear Information System (INIS)

    The authors investigated the selective uptake of various porphyrins atheromatous plaques. Grass and microscopic examination of atherosclorotic rabbit aortas under ultraviolet light 48 hours after porphyrin administration disclosed porphyrin fluorescence exclusively on the plaques. As judged from the fluorescence emission, the order of affinity of the porphyrins for plaque is as follows: photofrin II (PF II) > hematoporphyrin derivative (HPD) > tetrasulfonatophenyl porphyrin (TPPS) ? hydroxyethylvinyldeuteroporphyrin (HVD), hematoporphyrin (HP). The potential application of intravascular irradiation of plaques labeled with porphyrins in the treatment of atheroma can be investigated using the animal model. Matching the irradiation light wave length to the porphyrin absorption peak allows specific effects to be directed to the plaque without damaging the normal vessel wall

  11. Soil-gas radon as seismotectonic indicator in Garhwal Himalaya.

    Science.gov (United States)

    Ramola, R C; Prasad, Yogesh; Prasad, Ganesh; Kumar, Sushil; Choubey, V M

    2008-10-01

    Research on earthquake-related radon monitoring has received enormous attention recently. Anomalous behaviour of radon in soil and groundwater can be used as a reliable precursor for an impending earthquake. While earthquake prediction may not yet be possible, earthquake prediction research has greatly increased our understanding of earthquake source mechanisms, the structural complexities of fault zones, and the earthquake recurrence interval, expected at a given location. This paper presents some results of continuous monitoring of radon in soil-gas in Garhwal Himalaya, India. Daily soil-gas radon monitoring with seismic activity and meteorological parameters were performed in the same laboratory system, located at H.N.B. Garhwal University Campus, Tehri Garhwal, India. Radon anomalies along with meteorological parameters were found to be statistically significant for the seismic events within the magnitudes M2.0-M6.0 and epicentral distances of 16-250 km from the monitoring station. The frequent positive and negative anomalies with constant environmental perturbation indicate the opening and closing of micro cracks within the volume of dilatancy by strain energy. The spike-like and sharp peak anomalies were recorded before, during and after earthquakes occurred in the area. The variations in radon concentrations in soil-gas are found to be correlated with seismic activities in the Garhwal Himalaya. The correlation between radon level and meteorological parameters is also discussed. PMID:18502650

  12. Spatiotemporal Perturbations of Pore fluid Pressure in Kumaon Himalayas

    Science.gov (United States)

    Mannu, U.; Nandan, S.

    2012-12-01

    Convergence of Indian and Eurasian Plate induces significant seismic activity in the regions around the plate boundaries and pose a serious seismic risk to population living around Himalayas. As important as this area is; the studies relating to seismic risk evaluation has been limited and severely inadequate. Advent of newer techniques and the seismic deployment done by National Geophysical Research Institute during 2004 and 2008 for collection of high quality data enables us to study the stress and pore fluid pressure state and rate changes in space and time to assess the seismic risk. Many studies have predicated the occurrence of earthquake sequences on overpressurized fluids which lead to the failure of the faults. Knowledge about pore fluid pressure at hypocentral depths can provide critical insights in to risk evaluation as pore fluid pressure and triggering of events are closely related. The methodology of Focal Mechanism Tomography developed by Terakawa Toshiko (2010) enables us to map a three dimensional distribution of pore fluid pressure. The scheme has been shown to exhibit good reliability in previous studies and has been applied to many seismically active regions. We make use of this methodology to study the spatiotemporal changes in pore fluid pressure at hypocentral depths in Kumaon Himalaya region. We analyzed well constrained 785 shallow events (Depthblack stars) which were analyzed to give focal mechanism for further analysis. The blue triangles represent the stations which were deployed during the period 2004-2008 for collection of this data.

  13. Potential of vetiver (vetiveria zizanioides l.) grass in removing selected pahs from diesel contaminated soil

    International Nuclear Information System (INIS)

    Phytoremediation has been renowned as an encouraging technology for the remediation of polycyclic aromatic hydrocarbon (PAH)-contaminated soils, little is known about how plant species behave during the process of PAH phytoremediation. Therefore, the aim of this study was to investigate the effectiveness of vetiver (Vetiveria zizanioides L.) plant in PAH phytoremediation and extraction potential of Vetiveria zizanioides for selected PAHs from the diesel contaminated soil. The field soil samples were spiked with varying concentrations (0.5% and 1%) of diesel and used for pot experiment which was conducted in greenhouse. Vetiver grass was used as experimental plant. Physico-chemical analysis of soil was performed before and after the experiment. Concentration of selected PAHs i.e. phenanthrene, pyrene and benzo(a)pyrene in soil was determined using HPLC. Plant parameters such as root/shoot length and dry mass were compared after harvest. Concentrations of PAHs were also determined in plant material and in soils after harvesting. Result showed that initial concentration of phenanthrene was significantly different from final concentration in treatments in which soil was spiked with diesel. Initial and final concentration of pyrene in soil was also significantly different from each other in two treatments in which soil was spiked with 1% diesel. Pyrene concentration was significantly different in roots and shoots of plants while benzo(a)pyrene concentration in treatments in which soil was spiked with diesel was also significantly different from roots and shoots. Phenanthrene was less extracted by the plant in all the treatments and it was present in higher concentration in soil as compared to plant. Our results indicate that vetiver grass has effectively removed PAHs from soil consequently a significantly higher root and shoot uptake of PAHs was observed than control treatments. Study concludes Vetiveria zizanioides as potentially promising plant specie for the removal of PAHs from diesel contaminated soil. (author)

  14. Identifying potential clinical syndromes of hepatocellular carcinoma using PSO-based hierarchical feature selection algorithm.

    Science.gov (United States)

    Ji, Zhiwei; Wang, Bing

    2014-01-01

    Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Clinical symptoms attributable to HCC are usually absent, thus often miss the best therapeutic opportunities. Traditional Chinese Medicine (TCM) plays an active role in diagnosis and treatment of HCC. In this paper, we proposed a particle swarm optimization-based hierarchical feature selection (PSOHFS) model to infer potential syndromes for diagnosis of HCC. Firstly, the hierarchical feature representation is developed by a three-layer tree. The clinical symptoms and positive score of patient are leaf nodes and root in the tree, respectively, while each syndrome feature on the middle layer is extracted from a group of symptoms. Secondly, an improved PSO-based algorithm is applied in a new reduced feature space to search an optimal syndrome subset. Based on the result of feature selection, the causal relationships of symptoms and syndromes are inferred via Bayesian networks. In our experiment, 147 symptoms were aggregated into 27 groups and 27 syndrome features were extracted. The proposed approach discovered 24 syndromes which obviously improved the diagnosis accuracy. Finally, the Bayesian approach was applied to represent the causal relationships both at symptom and syndrome levels. The results show that our computational model can facilitate the clinical diagnosis of HCC. PMID:24745007

  15. Beyond EICA: understanding post-establishment evolution requires a broader evaluation of potential selection pressures

    Directory of Open Access Journals (Sweden)

    Joshua Atwood

    2011-10-01

    Full Text Available Research on post-establishment evolution in nonnative plant populations has focused almost exclusively on testing the Evolution of Increased Competitive Ability (EICA hypothesis, which posits that the lack of specialized herbivores in the invaded range drives evolution in nonnative plant populations. Fifteen years of conflicting EICA test results suggest that selection pressures other than specialized herbivory are important in driving post-establishment evolution in invasive species. Alternative hypotheses, such as the Evolution of Reduced Competitive Ability (ERCA hypothesis, have been proposed but have received little attention or testing. We argue that the lack of consensus across studies that test EICA may be due in part to the lack of consistent definitions and varying experimental design parameters, and that future research in this field would benefit from new methodological considerations. We examined previous work evaluating post-establishment evolution and evaluated the range of study systems and design parameters used in testing the EICA hypothesis. Our goal was to identify where different uses of ecological terms and different study parameters have hindered consensus and to suggest a path forward to move beyond EICA in post-establishment evolution studies. We incorporated these methods into a design framework that will increase data harmony across future studies and will facilitate examinations of any potential selection pressure driving evolution in the invaded range.

  16. Unveiling the metabolic potential of two soil-derived microbial consortia selected on wheat straw.

    Science.gov (United States)

    Jiménez, Diego Javier; Chaves-Moreno, Diego; van Elsas, Jan Dirk

    2015-01-01

    Based on the premise that plant biomass can be efficiently degraded by mixed microbial cultures and/or enzymes, we here applied a targeted metagenomics-based approach to explore the metabolic potential of two forest soil-derived lignocellulolytic microbial consortia, denoted RWS and TWS (bred on wheat straw). Using the metagenomes of three selected batches of two experimental systems, about 1.2?Gb of sequence was generated. Comparative analyses revealed an overrepresentation of predicted carbohydrate transporters (ABC, TonB and phosphotransferases), two-component sensing systems and ?-glucosidases/galactosidases in the two consortia as compared to the forest soil inoculum. Additionally, "profiling" of carbohydrate-active enzymes showed significant enrichments of several genes encoding glycosyl hydrolases of families GH2, GH43, GH92 and GH95. Sequence analyses revealed these to be most strongly affiliated to genes present on the genomes of Sphingobacterium, Bacteroides, Flavobacterium and Pedobacter spp. Assembly of the RWS and TWS metagenomes generated 16,536 and 15,902 contigs of ?10?Kb, respectively. Thirteen contigs, containing 39 glycosyl hydrolase genes, constitute novel (hemi)cellulose utilization loci with affiliation to sequences primarily found in the Bacteroidetes. Overall, this study provides deep insight in the plant polysaccharide degrading capabilities of microbial consortia bred from forest soil, highlighting their biotechnological potential. PMID:26343383

  17. Objective selection of EEG late potentials through residual dependence estimation of independent components.

    Science.gov (United States)

    Milanesi, M; James, C J; Martini, N; Menicucci, D; Gemignani, A; Ghelarducci, B; Landini, L

    2009-08-01

    This paper presents a novel method to objectively select electroencephalographic (EEG) cortical sources estimated by independent component analysis (ICA) in event-related potential (ERP) studies. A proximity measure based on mutual information is employed to estimate residual dependences of the components that are then hierarchically clustered based on these residual dependences. Next, the properties of each group of components are evaluated at each level of the hierarchical tree by two indices that aim to assess both cluster tightness and physiological reliability through a template matching process. These two indices are combined in three different approaches to bring to light the hierarchical structure of the cluster organizations. Our method is tested on a set of experiments with the purpose of enhancing late positive ERPs elicited by emotional picture stimuli. Results suggest that the best way to look for physiologically plausible late positive potential (LPP) sources is to explore in depth the tightness of those clusters that, taken together, best resemble the template. According to our results, after brain sources clustering, LPPs are always identified more accurately than from ensemble-averaged raw data. Since the late components of an ERP involve the same associative areas, regardless of the modality of stimulation or specific tasks administered, the proposed method can be simply adapted to other ERP studies, and extended from psychophysiological studies to pathological or sport training evaluation support. PMID:19550025

  18. Antimicrobial potential of immobilized Lactococcus lactis subsp. lactis ATCC 11454 against selected bacteria.

    Science.gov (United States)

    Millette, M; Smoragiewicz, W; Lacroix, M

    2004-06-01

    Immobilization of living cells of lactic acid bacteria could be an alternative or complementary method of immobilizing organic acids and bacteriocins and inhibit undesirable bacteria in foods. This study evaluated the inhibition potential of immobilized Lactococcus lactis subsp. lactis ATCC 11454 on selected bacteria by a modified method of the agar spot test. L. lactis was immobilized in calcium alginate (1 to 2%)-whey protein concentrate (0 and 1%) beads. The antimicrobial potential of immobilized L. lactis was evaluated in microbiological media against pathogenic bacteria (Escherichia coli, Salmonella, and Staphylococcus aureus) or Pseudomonas putida, a natural meat contaminant, and against seven gram-positive bacteria used as indicator strains. Results obtained in this study indicated that immobilized L. lactis inhibited the growth of S. aureus, Enterococcus faecalis, Enterococcus faecium, Lactobacillus curvatus, Lactobacillus sakei, Kocuria varians, and Pediococcus acidilactici. Only 4 h of incubation at 35 degrees C resulted in a clear inhibition zone around the beads that increased with time. With the addition of 10 mM of a chelating agent (EDTA) to the media, results showed growth inhibition of E. coli; however, P. putida and Salmonella Typhi were unaffected by this treatment. These results indicate that immobilized lactic acid bacteria strains can be successfully used to produce nisin and inhibit bacterial growth in semisolid synthetic media. PMID:15222547

  19. In vitro selection of bacteria with potential for use as probiotics in marine shrimp culture

    Directory of Open Access Journals (Sweden)

    Felipe do Nascimento Vieira

    2013-08-01

    Full Text Available The objective of this work was to isolate strains of lactic acid bacteria with probiotic potential from the digestive tract of marine shrimp (Litopenaeus vannamei, and to carry out in vitro selection based on multiple characters. The ideotype (ideal proposed strain was defined by the highest averages for the traits maximum growth velocity, final count of viable cells, and inhibition halo against nine freshwater and marine pathogens, and by the lowest averages for the traits duplication time and resistance of strains to NaCl (1.5 and 3%, pH (6, 8, and 9, and biliary salts (5%. Mahalanobis distance (D² was estimated among the evaluated strains, and the best ones were those with the shortest distances to the ideotype. Ten bacterial strains were isolated and biochemically identified as Lactobacillus plantarum (3, L. brevis (3, Weissella confusa (2, Lactococcus lactis (1, and L. delbrueckii (1. Lactobacillus plantarum strains showed a wide spectrum of action and the largest inhibition halos against pathogens, both Gram-positive and negative, high growth rate, and tolerance to all evaluated parameters. In relation to ideotype, L. plantarum showed the lowest Mahalanobis (D² distance, followed by the strains of W. confusa, L. brevis, L. lactis, and L. delbrueckii. Among the analyzed bacterial strains, those of Lactobacillus plantarum have the greatest potential for use as a probiotic for marine shrimp.

  20. Objective selection of EEG late potentials through residual dependence estimation of independent components

    International Nuclear Information System (INIS)

    This paper presents a novel method to objectively select electroencephalographic (EEG) cortical sources estimated by independent component analysis (ICA) in event-related potential (ERP) studies. A proximity measure based on mutual information is employed to estimate residual dependences of the components that are then hierarchically clustered based on these residual dependences. Next, the properties of each group of components are evaluated at each level of the hierarchical tree by two indices that aim to assess both cluster tightness and physiological reliability through a template matching process. These two indices are combined in three different approaches to bring to light the hierarchical structure of the cluster organizations. Our method is tested on a set of experiments with the purpose of enhancing late positive ERPs elicited by emotional picture stimuli. Results suggest that the best way to look for physiologically plausible late positive potential (LPP) sources is to explore in depth the tightness of those clusters that, taken together, best resemble the template. According to our results, after brain sources clustering, LPPs are always identified more accurately than from ensemble-averaged raw data. Since the late components of an ERP involve the same associative areas, regardless of the modality of stimulation or specific tasks administered, the proposed method can be simply adapted to other ERP studies, and extended from psychophysiological studies to pathological or sport training evaluation support

  1. Characterization of the diversity of mycosporine-like amino acids in lichens from high altitude region of Himalaya.

    Science.gov (United States)

    Shukla, Vertika; Kumari, Rupender; Patel, Davendra K; Upreti, Dalip K

    2016-01-01

    Lichens are tolerant to a number of environmental variables including high-intensity solar radiations, which is mainly due to the presence of chemical substances in the thallus. Especially, cyanobacterial lichens synthesize a unique class of chemical substances known as mycosporine-like amino acids (MAAs) the primary characteristic of which is strong ultraviolet (UV) absorption between 300 and 360 nm. In view of its UV-protecting potential, the applicability of mass spectral fragmentation using electrospray ionization tandem mass spectrometric analysis for the characterization of MAAs in lichen samples was explored. MAA compounds were characterized in four cyanobacteria-containing lichen species belonging to genus Peltigera, Stereocaulon and Lobaria. Among them, Peltigera and Lobaria are true cyanobacteria containing lichens (cyanolichens) while Stereocaulon is a tripartite lichen, as it contains both green algae (in the thallus) and cyanobacteria (in the cephalodia), collected from higher altitudes of Himalaya (Tungnath-Chopta in Garhwal Himalaya, 3432 m) from an exposed locality experiencing high light intensity. Mass spectral data of distinctive fragmentation pattern revealed that all the four species have good diversity of MAA compounds, especially Lobaria retigera was found to be enriched with highest diversity of oxo and imino MAAs. Overall, different numbers of oxo and imino MAA compounds were detected in the remaining lichen species. Good diversity of imino MAAs has ecological significance which is required to be investigated further. Moreover, the impressive diversity characterized in each lichen species suggests that lichens should be thoroughly studied for their MAAs contents. PMID:26286672

  2. Screening of CHP Potential at Federal Sites in Select Regions of the U.S.

    Energy Technology Data Exchange (ETDEWEB)

    Energy Nexus Group, . .

    2002-02-25

    Combined Cooling Heat and Power (CHP) is a master term for onsite power generation technologies that sequentially produce electrical or mechanical energy and useful thermal energy. Some form of CHP has existed for more than 100 years and it is now achieving a greater level of acceptance due to an increasing need for reliable power service and energy cost management. Capturing and using the heat produced as a byproduct of generating electricity from fuel sources increases the usable energy that can be obtained from the original fuel source. CHP technologies have the potential to reduce energy consumption through increased efficiency--decreasing energy bills as well as pollution. The EPA recognizes CHP as a potent climate change mitigation measure. The U.S. Department of Energy (D.O.E.) Federal Energy Management Program (FEMP) is assisting Federal agencies to realize their energy efficiency goals. CHP is an efficiency measure that is receiving growing attention because of its sizable potential to provide efficiency, environmental, and reliability benefits. CHP therefore benefits the host facility, the electric infrastructure, and the U.S. society as a whole. This report and study seeks to make a preliminary inquiry into near term CHP opportunities for federal facilities in selected U.S. regions. It offers to help focus the attention of policy makers and energy facility managers on good candidate facilities for CHP. First, a ranked list of high potential individual sites is identified. Then, several classes of federal facilities are identified for the multiple opportunities they offer as a class. Recommendations are then offered for appropriate next steps for the evaluation and cost effective implementation of CHP. This study was designed to ultimately rank federal facilities in terms of their potential to take advantage of CHP economic and external savings in the near term. In order to best serve the purposes of this study, projections have been expressed in terms of sizing CHP to thermal and electrical estimates. The table below is a summary of findings of CHP potential for those federal facilities that chose to participate in the screening process. The study focused on three U.S. regions: California, Texas, and New York/New England. All federal facilities in these three regions with reported building space greater than 100,000 square feet were initial targets to contact and offer CHP screening services. Ranking criteria were developed to screen sites for near term CHP potential. The potential site list was pared down for a variety of reasons including site- specific and agency wide decisions not to participate, desk audit assessments, and untraceable contact information. The results are based upon the voluntary participation of those sites we were able to contact, so they reflect a fraction of the total potential CHP opportunities at federal government facilities.

  3. Carbon and oxygen isotope changes in Siwalik soils from Nepal Himalaya

    International Nuclear Information System (INIS)

    Siwalik sediments of lower Himalayas are derived from the erosion of the rocks from higher reaches and deposited in the foreland basin. These group of sediments are formed over the time span of last ?20 Ma

  4. A Probabilistic Estimate of the Most Perceptible Earthquake Magnitudes in the NW Himalaya and Adjoining Regions

    Science.gov (United States)

    Yadav, R. B. S.; Koravos, G. Ch.; Tsapanos, T. M.; Vougiouka, G. E.

    2015-02-01

    NW Himalaya and its neighboring region (25°-40°N and 65°-85°E) is one of the most seismically hazardous regions in the Indian subcontinent, a region that has historically experienced large to great damaging earthquakes. In the present study, the most perceptible earthquake magnitudes, M p, are estimated for intensity I = VII, horizontal peak ground acceleration a = 300 cm/s2 and horizontal peak ground velocity v = 10 cm/s in 28 seismogenic zones using the two earthquake recurrence models of Kijko and Sellevoll (Bulletin of the Seismological Society of America 82(1):120-134 1992 ) and Gumbel's third asymptotic distribution of extremes (GIII). Both methods deal with maximum magnitudes. The earthquake perceptibility is calculated by combining earthquake recurrence models with ground motion attenuation relations at a particular level of intensity, acceleration and velocity. The estimated results reveal that the values of M p for velocity v = 10 cm/s show higher estimates than corresponding values for intensity I = VII and acceleration a = 300 cm/s2. It is also observed that differences in perceptible magnitudes calculated by the Kijko-Sellevoll method and GIII statistics show significantly high values, up to 0.7, 0.6 and 1.7 for intensity, acceleration and velocity, respectively, revealing the importance of earthquake recurrence model selection. The estimated most perceptible earthquake magnitudes, M p, in the present study vary from M W 5.1 to 7.7 in the entire zone of the study area. Results of perceptible magnitudes are also represented in the form of spatial maps in 28 seismogenic zones for the aforementioned threshold levels of intensity, acceleration and velocity, estimated from two recurrence models. The spatial maps show that the Quetta of Pakistan, the Hindukush-Pamir Himalaya, the Caucasus mountain belt and the Himalayan frontal thrust belt (Kashmir-Kangra-Uttarkashi-Chamoli regions) exhibit higher values of the most perceptible earthquake magnitudes ( M W > 6.0). These spatially-distributed values indicate good agreement with high seismic hazard zones in previously published hazard maps based on seismicity, maximum expected earthquake magnitudes during specific time intervals and maximum expected acceleration. These maps have useful implications in preparing earthquake selection criteria for the anti-seismic design of non-critical structures in the study region.

  5. Conflicting selection on diaspore traits limits the evolutionary potential of seed dispersal by ants.

    Science.gov (United States)

    Manzaneda, Antonio J; Rey, P J; Alcántara, J M

    2009-07-01

    Conflicts of selection on diaspore traits throughout the dispersal cycle can limit the evolutionary consequences of seed dispersal. However, these conflicts have never been investigated in directed dispersal systems. We explored conflicts of selection through life stages of dispersal in the myrmecochorous herb Helleborus foetidus. Seeds are subject to two contrasting partial selective scenarios. Undispersed seeds are subject to positive directional selection on seed size characters, whereas seeds dispersed are subject to stabilizing selection for size. In both scenarios, seedling establishment determined the magnitude and direction of selection. This does not reflect ant preferences for seed size. However, total selection still depends largely on ant activity, as ants control the relative importance of each selective scenario. We advocate the use of analytical approaches combining multiplicative fitness and microenvironment-specific selection to more realistically estimate the realized selection on traits functional during several life stages. This approach may be extended to any organism dispersing offspring to different environments. PMID:19460082

  6. High altitude survival: conflicts between pastoralism and wildlife in the Trans-Himalaya

    OpenAIRE

    MISHRA, C

    2001-01-01

    Keywords : Pastoralism, agriculture, wildlife, Himalaya, competition, bharal, yak, livestock, snow leopard, wolf, herbivore, ungulate, resource, rangeland, steppe, mountainHow harmonious is the coexistence between pastoralism and wildlife? This thesis is a response to repeated calls for a better understanding of pastoralism and its impacts on wildlife in India. Based on studies in the high altitude rangelands of the Trans-Himalaya that have a grazing history of over three millennia, I attempt...

  7. Medicinal flora and ethnoecological knowledge in the Naran Valley, Western Himalaya, Pakistan

    OpenAIRE

    Khan Shujaul M; Page Sue; Ahmad Habib; Shaheen Hamayun; Ullah Zahid; Ahmad Mushtaq; Harper David M

    2013-01-01

    Abstract Background Mountain ecosystems all over the world support a high biological diversity and provide home and services to some 12% of the global human population, who use their traditional ecological knowledge to utilise local natural resources. The Himalayas are the world's youngest, highest and largest mountain range and support a high plant biodiversity. In this remote mountainous region of the Himalaya, people depend upon local plant resources to supply a range of goods and services...

  8. A general definition of the heritable variation that determines the potential of a population to respond to selection.

    Science.gov (United States)

    Bijma, Piter

    2011-12-01

    Genetic selection is a major force shaping life on earth. In classical genetic theory, response to selection is the product of the strength of selection and the additive genetic variance in a trait. The additive genetic variance reflects a population's intrinsic potential to respond to selection. The ordinary additive genetic variance, however, ignores the social organization of life. With social interactions among individuals, individual trait values may depend on genes in others, a phenomenon known as indirect genetic effects. Models accounting for indirect genetic effects, however, lack a general definition of heritable variation. Here I propose a general definition of the heritable variation that determines the potential of a population to respond to selection. This generalizes the concept of heritable variance to any inheritance model and level of organization. The result shows that heritable variance determining potential response to selection is the variance among individuals in the heritable quantity that determines the population mean trait value, rather than the usual additive genetic component of phenotypic variance. It follows, therefore, that heritable variance may exceed phenotypic variance among individuals, which is impossible in classical theory. This work also provides a measure of the utilization of heritable variation for response to selection and integrates two well-known models of maternal genetic effects. The result shows that relatedness between the focal individual and the individuals affecting its fitness is a key determinant of the utilization of heritable variance for response to selection. PMID:21926298

  9. Selective oxidation of methionine residues in apolipoprotein A-I and its potential biological consequences

    International Nuclear Information System (INIS)

    The earliest stages of HDL oxidation are accompanied by the oxidation of specific Met residues in apolipoprotein AI and AII and the formation of Met sulfoxides (Met(O)) has been proposed to play a significant role in the reduction and hence detoxification of lipid hydroperoxides associated with HDL. Oxidation of HDL may generally decrease the anti-atherogenic properties of this lipoprotein, although both, the inhibition and the enhancement of cholesterol removal from cells has been reported for different types of oxidation. In light of these findings we have investigated the secondary structure, lipid affinity, LCAT activation and cholesterol-efflux promoting properties of native and selectively oxidized apo A-I(apo A-I+32, containing Met(O) at Metl12 and Metl48) in purified or reconstituted forms. Data obtained by circular dichroism revealed that selective oxidation of Met residues 112 and 148 does not alter alpha helicity of the protein in solution, indicating that this oxidation is not sufficient to influence significantly this type of secondary structure of apo A-I in its 'lipid-free' form. The lipid affinity of native apo A-I and apo A-I+32 was determined as the rate of clearance of DMPC multilamellar to small unilamellar vesicles. Compared with the native protein, apo A-I+32 induced a 2-3 fold faster rate of clearance, suggesting that the increased hydrophilicity due Met(O) increased the rate for protein-lipid interactions. Met residues 112 and 148 reside in the hydrophobic faces of helices 5 and 7, and both these regions have been suggested to be important for both, LCAT activation and cholesterol efflux. Kinetic experiments have revealed that the affinity for LCAT is comparable for HDL reconstituted with either apo A-I or apo A-I+32. Efflux of [3H]-cholesterol from lipid-laden human monocytederived macrophages to isolated apolipoproteins was enhanced for apo A-I+32 compared with apo A-I, consistent with the DMPC clearance data. Together these findings suggest that selective oxidation of Met residues of apo A-I may enhance rather than diminish known antiatherogenic activities of the apolipoprotein. Thus, our results are consistent with the overall hypothesis that detoxification of lipid hydroperoxides by Met residues of apo A-I is potentially antiatherogenic

  10. Cloud-Aerosol Drivers of Reflective Roof and Solar Power Potential Benefits Across Selected Indian Cities

    Science.gov (United States)

    Millstein, D.; Fischer, M. L.

    2013-12-01

    Application of reflective roof surfaces is an adaptive strategy for sustainable warm-climate human environments that can improve human comfort for un-conditioned buildings, energy consumption for conditioned buildings, the urban heat island effect, and potentially net radiation absorbed by the earth. Here, we evaluate the (1) potential radiative benefits of installing cool roofs and (2) incoming surface radiation available for solar power generation across selected Indian cities using a combination of satellite data (MODIS and MERRA) and a radiative transfer model (RRTMG). The radiative transfer model was run multiple times at each time step and location in order to separate the effects of clouds and aerosols on top of the atmosphere outgoing shortwave radiation reflected from roofs and on bottom of the atmosphere incoming shortwave radiation available for solar power generation. Modeled downwelling shortwave radiation at the surface was first validated against measurements obtained from urban rooftops during the 9-month (June, 2011-March, 2012) a joint Indian-US Ganges Valley Aerosol Experiment (GVAX) campaign. Results show that model bias at two Indian cities, Nainital (-4.2% average midday bias) and Pantnagar (0.5% average midday bias) was small compared to the radiative benefit obtained from a typical increase in surface reflectance (e.g., 0.3-0.6). Although both cities are located in the northern state of Uttarakhand, differences in terrain type, pollution burdens and cloudiness allow for validation of the model across a wide range of conditions. For example, Nainital is located in complex terrain at an altitude of ~2,000 meters near the Himalayan Mountains while Pantnagar is located in a flat plain at an altitude of ~300 meters. Pantnagar had a larger aerosol burden than Nainital as the average aerosol optical depth at Pantnagar (0.47) was larger than Nainital (0.33). Nainital was cloudier, with clouds observed on 62% of the days during the validation period while clouds were observed in Pantnagar on only 47% of the days. We then extend the model analysis to major Indian cities including New Delhi, Mumbai, Kolkata, and Bangalore. Preliminary results indicate that total (anthropogenic and natural) aerosols reduce the additional top of the atmosphere outgoing radiation from the installation of reflective roofs by an average of 45-110 W m-2 at midday, with the high end of the range set at New Dehli and the low end of the range set at Nainital. Similarly, aerosols reduce total incoming surface radiation by 61-150 W m-2, hence reducing potential solar power generation by up to 25% at some locations depending on the utilization of direct vs. diffuse solar energy. Ongoing analysis will evaluate inter-annual trends and variation in cloud and aerosol effects along with spatial variation across each selected city, and 1st order estimates of the potential improvements to radiative benefit and solar power generation from improvements to air quality. The authors note that the methods employed in this work to estimate radiative benefits from air quality changes assume constant cloud fields and do not account for any aerosol-cloud indirect effects or effects from land-use change (i.e. increased surface albedo from wide-scale adoption of reflective roofs).

  11. Characteristics of potential gasifier fuels in selected regions of the Lake Victoria Basin

    Scientific Electronic Library Online (English)

    Geoffrey O., Mosiori; Charles O., Onindo; Paul, Mugabi; Susan B., Tumwebaze; Samuel, Bagabo; Rukundo B., Johnson.

    2015-06-01

    Full Text Available All countries in the Lake Victoria Basin depend mostly on hydroelectric power for the provision of energy. Gasification technology has a high potential for reducing biomass energy consumption whilst increasing access to modern energy services. The key aspect for the failure of gasification operation [...] s in the Lake Victoria Basin is inadequate adaptation of gasification equipment to fuel characteristics, lack of fuel specification and inappropriate material choice. We therefore investigated the thermo-chemical characterisation of six biomass fuels, namely Pinus caribaea, Calitris robusta, Cupressus lusitanica, Eucalyptus grandis, Pinus patula and sugarcane bagasse from selected regions of the Lake Victoria Basin. Ultimate analysis was done using a Flash 2000 elemental analyser. Moisture content, ash content and volatile matter were determined in oven and muffle furnaces while heating values were determined using a Gallenkamp calorimeter. The mean percentage levels obtained indicate that all six biomass fuels had a mean range for nitrogen of 0.07±0.2-0.25±0.07%, for carbon of 40.45±0.61-48.88±0.29%, for hydrogen of 4.32±0.13-5.59±0.18% and for oxygen of 43.41±1.58-51.1±0.64%. Moisture content ranged between 25.74±1.54% and 56.69±0.52%, ash content between 0.38±0.02% and 2.94±0.14%, volatile matter between 74.68±0.49% and 82.71±0.19% and fixed carbon between 14.35±0.33% and 24.74±0.27%. Heating values ranged between 16.95±0.10 MJ/kg and 19.48±0.42 MJ/kg. The results suggest that all six biomass fuels are potential biomass gasification materials.

  12. Screening of different Fusarium species to select potential species for the synthesis of silver nanoparticles

    Scientific Electronic Library Online (English)

    Swapnil C., Gaikwad; Sonal S., Birla; Avinash P., Ingle; Aniket K., Gade; Priscyla D., Marcato; Mahendra, Rai; Nelson, Duran.

    2013-12-01

    Full Text Available Onze diferentes espécies de Fusarium foram isoladas a partir de vários materiais vegetais infectados e selecionados para escolher uma espécie potencialmente importante para a síntese de nanopartículas de prata. Todos os isolados foram identificados com base nas características de cultivo e microscóp [...] icas usando as chaves de identificação de Fusarium. Para a confirmação e identificação preliminar dos isolados de espécies de Fusarium, a análise BLAST on-line foi utilizada. Das espécies isoladas onze mostraram a capacidade para a síntese de nanopartículas de prata. A síntese de nanopartículas de prata foi confirmada por espectroscopia de UV-Vis que monstrou um pico característico em torno de 420 nm. Além disso, a confirmação da síntese de nanopartículas de prata foi realizada utilizando a análise de rastreamento de nanoparticulas (nanoparticle tracking analysis-NTA), medidas de potencial zeta, espectroscopia de correlação de fótons (PCS), difratometria de raios X de pó (XRD), e microscopia eletrônica de transmissão (TEM). As menores nanopartículas de prata foram sintetizadas por F. oxysporum (3-25 nm), enquanto as maiores foram obtidas com F. solani (3-50 nm). Abstract in english Eleven different Fusarium species were isolated from various infected plant materials and screened to select a potential species for the synthesis of silver nanoparticles. All the isolates were identified on the basis of cultural and microscopic characteristics using Fusarium identification keys. Fo [...] r the confirmation of preliminary identified isolates of Fusarium species, online BLAST analysis was carried out. All the eleven species demonstrated the ability for synthesis of silver nanoparticles. This was confirmed by UV-Vis spectroscopy, which gave characteristic peak around 420 nm. Further confirmation of silver nanoparticles was carried out using nanoparticles tracking analysis (NTA), zeta potential, photon correlation spectroscopy (PCS), powder X-ray diffractometry (XRD) and transmission electron microscopy (TEM). The smallest size of silver nanoparticles was synthesized by F. oxysporum (3-25 nm) and largest size silver nanoparticles were synthesized by F. solani (3-50 nm).

  13. Pre-selecting potential sites for a low and intermediate level waste repository in Mexico

    International Nuclear Information System (INIS)

    The storage in surface or shallow depths is viable for radioactive waste of low and intermediate level which contains short half life radionuclide that will decay to insignificant radioactive levels in some decades and some long half life radionuclide but at very low concentrations. The site selection process for construction of radioactive waste storage facilities, that presents and adequate stability in long term, and predictable performance in future and the capacity to meet all the operational requirements, is one of the main tasks that challenge the agencies for waste disposition. Different regions of Mexican Republic have been investigated in order to satisfy basic criteria related with some subjects physiographic, geologic, geohydrologic s, tectonics and seismic, as well as other factors as population density. An analysis of the existing information provides reason to expect that the Central region could host a repository for low and intermediate level waste. One of the most promising sites for a surface-type repository is situated in this region. The analysis of the preliminary results from the investigations performed at this site, described in this paper, confirmed its potential suitability: the site has geological and geotechnical features suitable for a repository. (Author)

  14. Application of an artificial neural network model for selection of potential lung cancer biomarkers.

    Science.gov (United States)

    Ligor, Tomasz; Pater, Łukasz; Buszewski, Bogusław

    2015-06-01

    Determination of volatile organic compounds (VOCs) in the exhaled breath samples of lung cancer patients and healthy controls was carried out by SPME-GC/MS (solid phase microextraction- gas chromatography combined with mass spectrometry) analyses. In order to compensate for the volatile exogenous contaminants, ambient air blank samples were also collected and analyzed. We recruited a total of 123 patients with biopsy-confirmed lung cancer and 361 healthy controls to find the potential lung cancer biomarkers. Automatic peak deconvolution and identification were performed using chromatographic data processing software (AMDIS with NIST database). All of the VOCs sample data operation, storage and management were performed using the SQL (structured query language) relational database. The selected eight VOCs could be possible biomarker candidates. In cross-validation on test data sensitivity was 63.5% and specificity 72.4% AUC 0.65. The low performance of the model has been mainly due to overfitting and the exogenous VOCs that exist in breath. The dedicated software implementing a multilayer neural network using a genetic algorithm for training was built. Further work is needed to confirm the performance of the created experimental model. PMID:25944812

  15. Selection of a mineral binder with potentialities for the stabilization/solidification of aluminum metal

    International Nuclear Information System (INIS)

    Highlights: • Binders capable of reducing the pore solution pH compared with Portland cements are reviewed. • The binders are then tested against aluminum corrosion. • Corrosion of aluminum metal is minimal with magnesium phosphate cement. • The H2 release can be reduced still further by adding LiNO3 to the mixing solution. • Electrochemical characterizations show that aluminum tends to a passive state. - Abstract: In a strongly alkaline medium, such as that encountered in conventional cementitious materials based on Portland cement, aluminum metal is corroded, with continued production of hydrogen. In order to develop a mineral matrix having enhanced compatibility with aluminum, a literature review was first undertaken to identify binders capable of reducing the pore solution pH compared with Portland cement. An experimental study was then carried out to measure the hydrogen production resulting from corrosion of aluminum metal rods encapsulated in the different selected cement pastes. The best results were achieved with magnesium phosphate cement, which released very little hydrogen over the duration of the study. This production could be reduced still further by adding a corrosion inhibitor (lithium nitrate) to the mixing solution. Open circuit potential measurement and Electrochemical Impedance Spectroscopy of aluminum electrode encapsulated in two pastes based on Portland cement and magnesium phosphate cement showed different redox behaviors. In the Portland cement paste, the electrochemical data confirmed the corrosion of aluminum whereas this latter tended to a passive state in the magnesium phosphate binder

  16. Electrophysiological localization of distinct calcium potentials at selective somatodendritic sites in the substantia nigra

    DEFF Research Database (Denmark)

    Hounsgaard, J; Nedergaard, S

    1992-01-01

    The dendrites of dopaminergic neurons in the substantia nigra play a pivotal role in the neurochemical homeostasis of the nucleus. It is conceivable therefore that the cell body and dendrites of these nigral neurons possess distinct and independent electro-responsive features. By means of differential polarization through applied electric fields, the cell body and dendrites have been activated in effective isolation during intracellular recordings from pars compacta neurons in the substantia nigra in vitro. In one class of neurons, which discharge in a "phasic" fashion and are located in the rostral substantia nigra, the dendrites are shown to be the origin of classic low-threshold and high-threshold type calcium potentials: indeed the high-threshold conductance appears to be exclusively dendritic. By contrast, in a second, more caudally located cell type, which discharges rhythmically, a high-threshold calcium spike is located principally in the cell body. The differential localization of these calcium conductances in sub-populations of neurons is likely to determine the functions for the calcium responses in each type of neuron, and moreover highlight the dendrites as dynamic and selective components in the physiology of the substantia nigra. The presence, for example, of the high-threshold calcium conductance in the dendrites of only one class of neuron suggests that this sub-population plays a prominent role in non-classical phenomena of dendritic release of a variety of chemical mediators.

  17. PRODUCTION POTENTIALS AND THE PHYSICOCHEMICAL COMPOSITION OF SELECTED DUCK STRAINS: A MINI REVIEW

    Directory of Open Access Journals (Sweden)

    FREDERICK ADZITEY

    2012-01-01

    Full Text Available Physicochemical composition of meat is an important factor in human nutrition and contributes to the choice of food by mankind. In recent times humans are much conscious of the health benefits of what they consume. Emphasize on the consumption of balance diets have been given much attention. The consumption of organic foods, vegetables, fruits, foods high in fibre, foods of animal origin with less fat and cholesterol are among the food stuffs being upheld. Poultry meat, eggs and products are widely consumed worldwide without much religious restrictions. The high consumption of poultry meat is partly due to it ease for preparing different dishes and the development of a wide range of processed ready-to-eat meals incorporated with chicken as a major protein source. Poultry meat (white meat is known to be healthier than red meat probably due to its low calorie and lipid contents. Duck meat is comparable to that of chicken despite being red meat and it is a close alternative source of protein and other nutrients for humans. Duck meat is high in protein, iron, selenium and niacin; and lower in calories compared to many cuts of beef. This mini-review reports on the production potentials of ducks and the physicochemical composition of selected duck strains. It also reports on world duck population.

  18. Selection of a mineral binder with potentialities for the stabilization/solidification of aluminum metal

    Energy Technology Data Exchange (ETDEWEB)

    Cau Dit Coumes, C., E-mail: celine.cau-dit-coumes@cea.fr [Commissariat à l’Energie Atomique et aux Energies Alternatives, CEA/DEN/MAR/DTCD/SPDE, BP17171, 30207 Bagnols-sur-Cèze cedex (France); Lambertin, D.; Lahalle, H.; Antonucci, P. [Commissariat à l’Energie Atomique et aux Energies Alternatives, CEA/DEN/MAR/DTCD/SPDE, BP17171, 30207 Bagnols-sur-Cèze cedex (France); Cannes, C.; Delpech, S. [Institut de Physique Nucléaire, CNRS, Univ. Paris-Sud 11, 91406 Orsay Cedex (France)

    2014-10-15

    Highlights: • Binders capable of reducing the pore solution pH compared with Portland cements are reviewed. • The binders are then tested against aluminum corrosion. • Corrosion of aluminum metal is minimal with magnesium phosphate cement. • The H{sub 2} release can be reduced still further by adding LiNO{sub 3} to the mixing solution. • Electrochemical characterizations show that aluminum tends to a passive state. - Abstract: In a strongly alkaline medium, such as that encountered in conventional cementitious materials based on Portland cement, aluminum metal is corroded, with continued production of hydrogen. In order to develop a mineral matrix having enhanced compatibility with aluminum, a literature review was first undertaken to identify binders capable of reducing the pore solution pH compared with Portland cement. An experimental study was then carried out to measure the hydrogen production resulting from corrosion of aluminum metal rods encapsulated in the different selected cement pastes. The best results were achieved with magnesium phosphate cement, which released very little hydrogen over the duration of the study. This production could be reduced still further by adding a corrosion inhibitor (lithium nitrate) to the mixing solution. Open circuit potential measurement and Electrochemical Impedance Spectroscopy of aluminum electrode encapsulated in two pastes based on Portland cement and magnesium phosphate cement showed different redox behaviors. In the Portland cement paste, the electrochemical data confirmed the corrosion of aluminum whereas this latter tended to a passive state in the magnesium phosphate binder.

  19. Selection of a mineral binder with potentialities for the stabilization/solidification of aluminum metal

    Science.gov (United States)

    Cau Dit Coumes, C.; Lambertin, D.; Lahalle, H.; Antonucci, P.; Cannes, C.; Delpech, S.

    2014-10-01

    In a strongly alkaline medium, such as that encountered in conventional cementitious materials based on Portland cement, aluminum metal is corroded, with continued production of hydrogen. In order to develop a mineral matrix having enhanced compatibility with aluminum, a literature review was first undertaken to identify binders capable of reducing the pore solution pH compared with Portland cement. An experimental study was then carried out to measure the hydrogen production resulting from corrosion of aluminum metal rods encapsulated in the different selected cement pastes. The best results were achieved with magnesium phosphate cement, which released very little hydrogen over the duration of the study. This production could be reduced still further by adding a corrosion inhibitor (lithium nitrate) to the mixing solution. Open circuit potential measurement and Electrochemical Impedance Spectroscopy of aluminum electrode encapsulated in two pastes based on Portland cement and magnesium phosphate cement showed different redox behaviors. In the Portland cement paste, the electrochemical data confirmed the corrosion of aluminum whereas this latter tended to a passive state in the magnesium phosphate binder.

  20. Quantifying sources, transport, deposition, and radiative forcing of black carbon over the Himalayas and Tibetan Plateau

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Rudong; Wang, Hailong; Qian, Yun; Rasch, Philip J.; Easter, Richard C.; Ma, Po-Lun; Singh, Balwinder; Huang, Jianping; Fu, Qiang

    2015-01-01

    Black carbon (BC)particles over the Himalayas and Tibetan Plateau (HTP), both airborne and those deposited on snow, have been shown to affect snowmelt and glacier retreat. Since BC over the HTP may originate from a variety of geographical regions and emission sectors, it is essential to quantify the source-receptor relationships of BC in order to understand the contributions of natural and anthropogenic emissions and provide guidance for potential mitigation actions. In this study, we use the Community Atmosphere Model version 5 (CAM5) with a newly developed source tagging technique, nudged towards the MERRA meteorological reanalysis, to characterize the fate of BC particles emitted from various geographical regions and sectors. Evaluated against observations over the HTP and surrounding regions, the model simulation shows a good agreement in the seasonal variation of the near-surface airborne BC concentrations, providing confidence to use this modeling framework for characterizing BC source- receptor relationships. Our analysis shows that the relative contributions from different geographical regions and source sectors depend on seasons and the locations in the HTP. The largest contribution to annual mean BC burden and surface deposition in the entire HTP region is from biofuel and biomass (BB) emissions in South Asia, followed by fossil fuel (FF) emissions from South Asia, then FF from East Asia. The same roles hold for all the seasonal means except for the summer when East Asia FF becomes more important. For finer receptor regions of interest, South Asia BB and FF have the largest impact on BC in Himalayas and Central Tibetan Plateau, while East Asia FF and BB contribute the most to Northeast Plateau in all seasons and Southeast Plateau in the summer. Central Asia and Middle East FF emissions have relatively more important contributions to BC reaching Northwest Plateau, especially in the summer. Although the HTP local emissions only contribute about 10% of BC in the HTP, this contribution is extremely sensitive to changes in the local emissions. Lastly, we show that the annual mean radiative forcing (0.42 W m-2) due to BC in snow outweighs the BC dimming effect-0.3 W m-2)at the surface over the HTP, although the mean BC-in- snow forcing is likely overestimated. We find strong seasonal and sub -region variation with a peak value of 5W m-2 in the spring over Northwest Plateau. The annual mean dust-in-snow forcing is comparable to that of BC over the entire HTP but significantly larger than BC over the North east Plateau. Such a large forcing of BC in snow is sufficient to cause earlier snow melting and potentially contribute to the acceleration of glacier retreat

  1. Quantifying sources, transport, deposition, and radiative forcing of black carbon over the Himalayas and Tibetan Plateau

    Science.gov (United States)

    Zhang, R.; Wang, H.; Qian, Y.; Rasch, P. J.; Easter, R. C.; Ma, P.-L.; Singh, B.; Huang, J.; Fu, Q.

    2015-06-01

    Black carbon (BC) particles over the Himalayas and Tibetan Plateau (HTP), both airborne and those deposited on snow, have been shown to affect snowmelt and glacier retreat. Since BC over the HTP may originate from a variety of geographical regions and emission sectors, it is essential to quantify the source-receptor relationships of BC in order to understand the contributions of natural and anthropogenic emissions and provide guidance for potential mitigation actions. In this study, we use the Community Atmosphere Model version 5 (CAM5) with a newly developed source-tagging technique, nudged towards the MERRA meteorological reanalysis, to characterize the fate of BC particles emitted from various geographical regions and sectors. Evaluated against observations over the HTP and surrounding regions, the model simulation shows a good agreement in the seasonal variation in the near-surface airborne BC concentrations, providing confidence to use this modeling framework for characterizing BC source-receptor relationships. Our analysis shows that the relative contributions from different geographical regions and source sectors depend on season and location in the HTP. The largest contribution to annual mean BC burden and surface deposition in the entire HTP region is from biofuel and biomass (BB) emissions in South Asia, followed by fossil fuel (FF) emissions from South Asia, then FF from East Asia. The same roles hold for all the seasonal means except for the summer, when East Asia FF becomes more important. For finer receptor regions of interest, South Asia BB and FF have the largest impact on BC in the Himalayas and central Tibetan Plateau, while East Asia FF and BB contribute the most to the northeast plateau in all seasons and southeast plateau in the summer. Central Asia and Middle East FF emissions have relatively more important contributions to BC reaching the northwest plateau, especially in the summer. Although local emissions only contribute about 10% of BC in the HTP, this contribution is extremely sensitive to local emission changes. Lastly, we show that the annual mean radiative forcing (0.42 W m-2) due to BC in snow outweighs the BC dimming effect (-0.3 W m-2) at the surface over the HTP. We also find strong seasonal and spatial variation with a peak value of 5 W m-2 in the spring over the northwest plateau. Such a large forcing of BC in snow is sufficient to cause earlier snow melting and potentially contribute to the acceleration of glacier retreat.

  2. The Himalayas: barrier and conduit for gene flow.

    Science.gov (United States)

    Gayden, Tenzin; Perez, Annabel; Persad, Patrice J; Bukhari, Areej; Chennakrishnaiah, Shilpa; Simms, Tanya; Maloney, Trisha; Rodriguez, Kristina; Herrera, Rene J

    2013-06-01

    The Himalayan mountain range is strategically located at the crossroads of the major cultural centers in Asia, the Middle East and Europe. Although previous Y-chromosome studies indicate that the Himalayas served as a natural barrier for gene flow from the south to the Tibetan plateau, this region is believed to have played an important role as a corridor for human migrations between East and West Eurasia along the ancient Silk Road. To evaluate the effects of the Himalayan mountain range in shaping the maternal lineages of populations residing on either side of the cordillera, we analyzed mitochondrial DNA variation in 344 samples from three Nepalese collections (Newar, Kathmandu and Tamang) and a general population of Tibet. Our results revealed a predominantly East Asian-specific component in Tibet and Tamang, whereas Newar and Kathmandu are both characterized by a combination of East and South Central Asian lineages. Interestingly, Newar and Kathmandu harbor several deep-rooted Indian lineages, including M2, R5, and U2, whose coalescent times from this study (U2, >40 kya) and previous reports (M2 and R5, >50 kya) suggest that Nepal was inhabited during the initial peopling of South Central Asia. Comparisons with our previous Y-chromosome data indicate sex-biased migrations in Tamang and a founder effect and/or genetic drift in Tamang and Newar. Altogether, our results confirm that while the Himalayas acted as a geographic barrier for human movement from the Indian subcontinent to the Tibetan highland, it also served as a conduit for gene flow between Central and East Asia. PMID:23580401

  3. Solar Radiation Patterns and Glaciers in the Western Himalaya

    Science.gov (United States)

    Dobreva, I. D.; Bishop, M. P.

    2013-12-01

    Glacier dynamics in the Himalaya are poorly understood, in part due to variations in topography and climate. It is well known that solar radiation is the dominant surface-energy component governing ablation, although the spatio-temporal patterns of surface irradiance have not been thoroughly investigated given modeling limitations and topographic variations including altitude, relief, and topographic shielding. Glaciation and topographic conditions may greatly influence supraglacial characteristics and glacial dynamics. Consequently, our research objectives were to develop a GIS-based solar radiation model that accounts for Earth's orbital, spectral, atmospheric and topographic dependencies, in order to examine the spatio-temporal surface irradiance patterns on glaciers in the western Himalaya. We specifically compared irradiance patterns to supraglacial characteristics and ice-flow velocity fields. Shuttle Radar Mapping Mission (SRTM) 90 m data were used to compute geomorphometric parameters that were input into the solar radiation model. Simulations results for 2013 were produced for the summer ablation season. Direct irradiance, diffuse-skylight, and total irradiance variations were compared and related to glacier altitude profiles of ice velocity and land-surface topographic parameters. Velocity and surface information were derived from analyses of ASTER satellite data. Results indicate that the direct irradiance significantly varies across the surface of glaciers given local topography and meso-scale relief conditions. Furthermore, the magnitude of the diffuse-skylight irradiance varies with altitude and as a result, glaciers in different topographic settings receive different amounts of surface irradiance. Spatio-temporal irradiance patterns appear to be related to glacier surface conditions including supraglacial lakes, and are spatially coincident with ice-flow velocity conditions on some glaciers. Collectively, our results demonstrate that glacier sensitivity to climate change is also locally controlled by numerous multi-scale topographic parameters.

  4. Automated tube potential selection for standard chest and abdominal CT in follow-up patients with testicular cancer: comparison with fixed tube potential

    International Nuclear Information System (INIS)

    To evaluate prospectively, in patients with testicular cancer, the radiation dose-saving potential and image quality of contrast-enhanced chest and abdominal CT with automated tube potential selection. Forty consecutive patients with testicular cancer underwent contrast-enhanced arterio-venous chest and portal-venous abdominal CT with automated tube potential selection (protocol B; tube potential 80-140 kVp), which is based on the attenuation of the CT topogram. All had a first CT at 120 kVp (protocol A) using the same 64-section CT machine and similar settings. Image quality was assessed; dose information (CTDIvol) was noted. Image noise and attenuation in the liver and spleen were significantly higher for protocol B (P vol was significantly lower for protocol B compared to protocol A (reduction by 12%, P < 0.01). In patients with testicular cancer, radiation dose of chest and abdominal CT can be reduced with automated tube potential selection, while image quality is preserved. (orig.)

  5. Selected extracellular microRNA as potential biomarkers of multiple sclerosis activity--preliminary study.

    Science.gov (United States)

    Kacperska, Magdalena Justyna; Jastrzebski, Karol; Tomasik, Bartlomiej; Walenczak, Jakub; Konarska-Krol, Maria; Glabinski, Andrzej

    2015-05-01

    Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS). Four distinct disease courses are known, although approximately 90% of patients are diagnosed with the relapsing-remitting form (RRMS). The name "multiple sclerosis" pertains to the underlying pathology: the presence of demyelinating plaques in the CNS, in particular in the periventricular region, corpus callosum, cervical spine, and the cerebellum. There are ongoing efforts to discover biomarkers that would allow for an unequivocal diagnosis, assess the activity of inflammatory and neurodegenerative processes, or warn of disease progression. At present, small noncoding RNA particles-microRNA (miRNA, miR) seem to be particularly noteworthy, as they take part in posttranscriptional regulation of expression of various genes. Changes in composition as well as function of miRNA found in body fluids of MS patients are subjects of research, in the hope they prove accurate markers of MS activity. This preliminary study aims to evaluate the expression of selected extracellular microRNA particles (miRNA-let-7a, miRNA-92a, miRNA-684a) in patients experiencing MS relapse and remission, with healthy volunteers serving as a control group and to evaluate the correlation between miRNA expression and selected clinical parameters of those patients. Thirty-seven patients suffering from MS formed two examined groups: 20 patients undergoing relapse and 17 in remission. Thirty healthy volunteers formed the control group. All patients who were subjects to peripheral blood sampling had been hospitalized in the Department of Neurology and Stroke(1). Four milliliters of venous whole blood had been collected into EDTA tubes. The basis for the selection of the three particular miRNA investigated in this study (miRNA-let-7a, miRNA-92a, miRNA-684a) was a preliminary bioinformatic analysis of data compiled from several medical databases, including Ovid MEDLINE®, Embase, Cochrane Database of Systematic Reviews (CDSR), miRWalk, and miRBase. The isolation of extracellular microRNA from plasma was carried out using miRNeasy Mini Kit (Qiagen) reagents. The reverse transcription was carried out with TaqMan® MicroRNA Reverse Transcription Kit (Applied Biosystems), as per manufacturers' instructions. Standard microRNA TaqMan® tests (Applied Biosystems) were used for miRNA quantification. The qPCR were performed on a 7900 HT Fast Real-Time PCR System (Applied Biosystems) and analyzed using Sequence Detection System 2.3 software. In addition, all patients at the Department of Neurology and Stroke undergo a routine complete blood count with differential. The main objective of this study was to evaluate the expression of selected microRNA (has-miR-let-7a, miR-92a, and miR-648a) in the plasma of patients with MS during a relapse as well as in remission and attempt to correlate the acquired data with clinically relevant parameters of the disease. Finding such correlations may potentially lead to the use of miRNA as a biomarker of MS, which could help diagnose the disease and assess its severity and the efficacy of treatment. The difference in the expression of has-miR-let-7a in the remission group and the control group was statistically significant (p?=?0.002). Similarly, the expression of miRNA-648a in patients in remission was significantly different from the expression in the control group (p?=?0.02). Analysis of the correlation between the expression of miRNA-92a and the severity of the disease as measured by the EDSS scale in patients undergoing relapse showed significant negative linear correlation (r?=?-0.54, p?=?0.01). Higher miR-648a expression correlated with more frequent flare-ups in the joint group of patients in remission and relapse (p?=?0.03). This study is one of the few that demonstrate significantly changed expression of selected extracellular miRNA in plasma of MS patients and correlate those findings with clinical parameters. These observations may suggest that some miRNA subsets may be potential biomarkers for M

  6. Brief Communication: Contending estimates of early 21st century glacier mass balance over the Pamir-Karakoram-Himalaya

    Directory of Open Access Journals (Sweden)

    A. Kääb

    2014-11-01

    Full Text Available We present glacier thickness changes over the entire Pamir-Karakoram-Himalaya arc based on ICESat satellite altimetry data for 2003–2008. The strongest thinning (?1 is observed for the East Nyainqêntanglha Shan. Conversely, glaciers of the West Kunlun Shan are slightly gaining volume, and Pamir and Karakoram seem to be on the western edge of an anomaly rather than its centre. For the Ganges, Indus and Brahmaputra basins, the glacier mass change reaches ?22 ± 3 Gt yr?1, about 10% of the current glacier contribution to sea-level rise. For selected catchments over the study area we estimate glacier imbalance contributions to river runoff from a few percent to far over 10%. We highlight the importance of C-band penetration for studies based on the SRTM elevation model. To the very east and west of our study area, this penetration seems to be of larger magnitude and variability than previously assumed.

  7. Soil quality index as affected by different cropping systems in northwestern Himalayas.

    Science.gov (United States)

    Sofi, J A; Bhat, A G; Kirmai, N A; Wani, J A; Lone, Aabid H; Ganie, Mumtaz A; Dar, G I H

    2016-03-01

    Soil quality assessment provides a tool for evaluating the sustainability of soils under different crop cafeterias. Our objective was to develop the soil quality index for evaluating the soil quality indicators under different cropping systems in northwest Himalaya-India. Composite soil samples were taken from the study area from different cropping systems which include T1 (forest soil control), T2 (rice-oilseed, lower belts), T3 (rice-oilseed, higher belts), T4 (rice-oats), T5 (rice-fallow), T6 (maize-oats), T7 (maize-peas), T8 (apple), T9 (apple-beans), and T10 (apple-maize). Physical, chemical, and biological soil indicators were determined, and it was found that soil enzyme activities involved in nutrient cycling were significantly higher in forest soils, which were reflected in higher levels of available pool of nutrients. Carbon stocks were found significantly higher in forest soil which was translated in improved soil physical condition. Principal component analysis (PCA) was performed to reduce multidimensionality of data followed by scoring by homothetic transformation of the selected indicators. Pearson's interclass correlation was performed to avoid redundancy, and highly correlated variables were not retained. Inclusion of legumes in the apple orchard floor recorded highest soil quality rating across the treatments. Cereal-based cropping systems were found in lower soil quality rating; however, the incorporation of peas in the system improved soil health. PMID:26875075

  8. Interactions of biotic and abiotic environmental factors in an ectomycorrhizal symbiosis, and the potential for selection mosaics

    OpenAIRE

    Hoeksema Jason D; Piculell Bridget J; Thompson John N

    2008-01-01

    Abstract Background Geographic selection mosaics, in which species exert different evolutionary impacts on each other in different environments, may drive diversification in coevolving species. We studied the potential for geographic selection mosaics in plant-mycorrhizal interactions by testing whether the interaction between bishop pine (Pinus muricata D. Don) and one of its common ectomycorrhizal fungi (Rhizopogon occidentalis Zeller and Dodge) varies in outcome, when different combination...

  9. (110)-exposed gold nanocoral electrode as low onset potential selective glucose sensor.

    Science.gov (United States)

    Cheng, Ta-Ming; Huang, Ting-Kai; Lin, Huang-Kai; Tung, Sze-Ping; Chen, Yu-Liang; Lee, Chi-Young; Chiu, Hsin-Tien

    2010-10-01

    A straightforward electrochemical deposition process was developed to grow gold nanostructures, including nanocoral, nanothorn, branched belt, and nanoparticle, on carbon electrodes by reducing HAuCl4 under constant potentials in mixtures containing CTAC and/or NaNO3. Among the nanostructures, the quasi-one-dimensional nanocoral electrode showed the highest surface area. Because of this, it provided excellent electrochemical performances in cyclic voltammetric (CV) studies for kinetic-controlled enzyme-free glucose oxidation reactions. In amperometric studies carried out at 0.200 V in PBS (pH 7.40, 0.100 M), the nanocoral electrode showed the highest anodic current response. It also offered the greatest sensitivity, 22.6 ?AmM(-1)cm(-2), an extended linear range, 5.00×10(-2) mM to 3.00×10(1) mM, and a low detection limit, 1.00×10(1) ?m among the electrodes investigated in this study. In addition, the glucose oxidation by the nanocoral electrode started at -0.280 V, more negative than the one of using a commercial Au electrode as the working electrode. This is attributed to the presence of exposed Au (110) surfaces on the electrode. The feature was applied to oxidize glucose selectively in the presence of ascorbic acid (AA) and uric acid (UA), common interferences found in physiological analytes. With an applied voltage at -0.100 V, the AA oxidation (started at -0.080 V) can be avoided while the glucose oxidation still provides a significant response. PMID:20822135

  10. Genetic variation in a host-parasite association: potential for coevolution and frequency-dependent selection.

    Science.gov (United States)

    Carius, H J; Little, T J; Ebert, D

    2001-06-01

    Models of host-parasite coevolution assume the presence of genetic variation for host resistance and parasite infectivity, as well as genotype-specific interactions. We used the freshwater crustacean Daphnia magna and its bacterial microparasite Pasteuria ramosa to study genetic variation for host susceptibility and parasite infectivity within each of two populations. We sought to answer the following questions: Do host clones differ in their susceptibility to parasite isolates? Do parasite isolates differ in their ability to infect different host clones? Are there host clone-parasite isolate interactions? The analysis revealed considerable variation in both host resistance and parasite infectivity. There were significant host clone-parasite isolate interactions, such that there was no single host clone that was superior to all other clones in the resistance to every parasite isolate. Likewise, there was no parasite isolate that was superior to all other isolates in infectivity to every host clone. This form of host clone-parasite isolate interaction indicates the potential for coevolution based on frequency-dependent selection. Infection success of original host clone-parasite isolate combinations (i.e., those combinations that were isolated together) was significantly higher than infection success of novel host clone-parasite isolate combinations (i.e., those combinations that were created in the laboratory). This finding is consistent with the idea that parasites track specific host genotypes under natural conditions. In addition, correspondence analysis revealed that some host clones, although distinguishable with neutral genetic markers, were susceptible to the same set of parasite isolates and thus probably shared resistance genes. PMID:11475049

  11. Selective isolation and differentiation of a stromal population of human embryonic stem cells with osteogenic potential

    DEFF Research Database (Denmark)

    Harkness, Linda M; Mahmood, Amer

    2011-01-01

    The derivation of osteogenic cells from human embryonic stem cells (hESC) has been hampered by the absence of easy and reproducible protocols. hESC grown in feeder-free conditions, often show a sub population of fibroblast-like, stromal cells growing between the colonies. Thus, we examined the possibility that these cells represent a population of stromal (mesenchymal) stem cells (hESC-stromal). Two in house derived hES cell lines (Odense3 and KMEB3) as well as an externally derived cell line (Hues8) were transitioned to feeder-free conditions. A sub population of fibroblast-like cells established between the hESC colonies were isolated by selective adherence to hyaluronic acid-coated plates (100?g/ml) and were characterized using a combination of FACS analysis and staining. The cells were CD44(+), CD29(+), CD73(+), CD166(+), CD146(+), and CD105(+); and, Oct4(-), CD34(-), CD45(-) and CXCR4(-). When cultured in osteogenic differentiation media, up regulation of osteoblastic lineage markers (DLX5, MSX2, RUNX2, SPARC, ALP, COL1a1, BGLAP, IBSP, DCN, LOX-L4) and production of in vitro mineralized matrix was detected. hESC-stromal cells loaded on a carrier and implanted either subcutaneously or in a critical size calvarial defect in immune deficient mice for 10weeks, resulted in new bone formation and partial repair of the calvarial defect. In conclusion, hESC-stromal can be isolated from hESC cultures and represent a good source for obtaining cells with osteogenic differentiation potential suitable for regenerative medicine protocols.

  12. Narcissus and Leadership Potential:The measurement and implications of narcissism in leadership selection processes

    OpenAIRE

    Gimsø, Christian Enger

    2014-01-01

    Incorporating theoretical and empirical work from the literature on narcissism, it is postulated that narcissism poses a particular risk in leader selection settings. By appearing confident, charismatic, intelligent, and with a high self-esteem and authority, narcissists will slip through normal selection processes by resembling an implicit image of a prototypical leader for those that select and hire them. In three independent, yet connected studies, the role played by trait narcissism i...

  13. Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies

    DEFF Research Database (Denmark)

    Bennacef, Idriss; Salinas, Cristian A; Bonasera, Thomas A; Gunn, Roger N; Audrain, Hélène; Jakobsen, Steen; Nabulsi, Nabeel; Weinzimmer, David; Carson, Richard E; Huang, Yiyun; Holmes, Ian; Micheli, Fabrizio; Heidbreder, Christian; Gentile, Gabriella; Rossi, Tino; Laruelle, Marc

    2009-01-01

    Compound 1 is a potent and selective antagonist of the dopamine D(3) receptor. With the aim of developing a carbon-11 labeled ligand for the dopamine D(3) receptor, 1 was selected as a potential PET probe. [(11)C]1 was obtained by palladium catalyzed cross coupling using [(11)C]cyanide and 4 with a specific activity of 55.5+/-25.9GBq/micromol (1.5+/-0.7Ci/micromol). [(11)C]1 was tested in porcine and non-human primate models to assess its potential as a radioligand for PET imaging of the dopamin...

  14. Spatial prediction of landslide susceptibility in parts of Garhwal Himalaya, India, using the weight of evidence modelling.

    Science.gov (United States)

    Guri, Pardeep Kumar; Ray, P K Champati; Patel, Ramesh Chandra

    2015-06-01

    Garhwal Himalaya in northern India has emerged as one of the most prominent hot spots of landslide occurrences in the Himalaya mainly due to geological causes related to mountain building processes, steep topography and frequent occurrences of extreme precipitation events. As this region has many pilgrimage and tourist centres, it is visited by hundreds of thousands of people every year, and in the recent past, there has been rapid development to provide adequate roads and building infrastructure. Additionally, attempts are also made to harness hydropower by constructing tunnels, dams and reservoirs and thus altering vulnerable slopes at many places. As a result, the overall risk due to landslide hazards has increased many folds and, therefore, an attempt was made to assess landslide susceptibility using 'Weights of Evidence (WofE)', a well-known bivariate statistical modelling technique implemented in a much improved way using remote sensing and Geographic Information System. This methodology has dual advantage as it demonstrates how to derive critical parameters related to geology, geomorphology, slope, land use and most importantly temporal landslide distribution in one of the data scarce region of the world. Secondly, it allows to experiment with various combination of parameters to assess their cumulative effect on landslides. In total, 15 parameters related to geology, geomorphology, terrain, hydrology and anthropogenic factors and 2 different landslide inventories (prior to 2007 and 2008-2011) were prepared from high-resolution Indian remote sensing satellite data (Cartosat-1 and Resourcesat-1) and were validated by field investigation. Several combinations of parameters were carried out using WofE modelling, and finally using best combination of eight parameters, 76.5 % of overall landslides were predicted in 24 % of the total area susceptible to landslide occurrences. The study has highlighted that using such methodology landslide susceptibility assessment can be carried out in vast stretches of Himalaya in short time in order to assess the impact of development as well as climate change/variability. The resultant map can play a critical role in selecting areas for remedial measures for slope stabilisation as well planning for future development of the region. PMID:25944750

  15. Environmental impact assessment of mountain tourism in developing regions: A study in Ladakh, Indian Himalaya

    International Nuclear Information System (INIS)

    Mountain tourism in developing countries is becoming a growing environmental concern due to extreme seasonality, lack of suitable infrastructures and planning, and interference with fragile ecosystems and protected areas. This paper presents a study devoted to assess the adverse environmental impacts of tourism, and in particular of trekking-related activities, in Ladakh, Indian Himalaya. The proposed approach is based on the use of Geographical Information System (GIS) modeling and remote sensing imageries to cope with the lack of data that affect the region. First, stressors associated with trekking, and environmental receptors potentially affected were identified. Subsequently, a baseline study on stressors (trail use, waste dumping, camping, pack animal grazing and off-road driving) and receptors (soil, water, wildlife, vegetation) was conducted through field work, data collection, and data processing supported by GIS. Finally, impacts were modeled by considering the intensity of the stressors, and the vulnerability and the value of the receptors. The results were spatially aggregated into watershed units, and combined to generate composite impact maps. The study concluded that the most affected watersheds are located in the central and southeastern part of Ladakh, along some of the most visited trails and within the Hemis and the Tsokar Tsomoriri National parks. The main objective of the study was to understand patterns of tourism-induced environmental degradation, so as to support mitigation interventions, as well as the development of suitable tourism policies.

  16. Spatial Coupling Among Landslides, Geological Structures, Cataclinal Slopes, and Fluvial Knick Zones in Nepal Himalayas

    Science.gov (United States)

    Ojha, T. P.; DeCelles, P. G.

    2014-12-01

    This work aims to identify potential landslide hazard zones in the event of heavy precipitation and seismic activity by examining spatial relationships among existing landslides, earthquake epicenters, fault zones, cataclinal (dip) slopes, anaclinal (escarp) slopes, and river steepness index in the Nepal Himalaya. In order to understand this relationship we have mapped existing landslides on Google Earth images and ESRI base maps, assembled high-resolution digital topographic data by digitizing Nepal Government published topographic maps, and gathered geological data from detailed field mapping and compilation of published geological maps. Slope angle and aspect, and dip direction and angle were extracted from GIS-based digital topographical and geological datasets to develop the new slope maps with cataclinal (dip) and anaclinal (escarp) slope distributions. Longitudinal river profiles were also extracted from high resolution DEM's derived from manually digitized contours. The slope maps with cataclinal and anaclinal slope distributions, earthquake epicenters, major geological structures, longitudinal river profiles, and landslide inventories were visualized in ESRI ArcMap 10.2 to examine the spatial correlation among landslides, fault zones, cataclinal slopes and river steepness index. We have found that landslides are spatially correlated with cataclinal slopes and fluvial knick zones with high steepness index in certain thrust boundaries. The main finding of this work is that the topographic slope threshold alone is a crude measure of landslide susceptibility. The analysis of slope using the geometric relationship among topography and geological bedding is crucial for determining landslide susceptibility in the Himalayan region.

  17. Evolution and outburst risk analysis of moraine-dammed lakes in the central Chinese Himalaya

    Science.gov (United States)

    Shijin, Wang; Shitai, Jiao

    2015-04-01

    The recent evolution and outburst risk of two typical moraine-dammed lakes, Galong and Gangxi, central Chinese Himalaya, are analyzed using topographic maps from 1974 and Landsat satellite imagery acquired in 1988, 2000 and 2014. The datasets show the areas of Galong and Gangxi lakes increasing at rates of 0.45 and 0.34 km2/year during the period 1974-2014, an expansion of 501% and 107%, respectively, in the past 41 years, while the areas of the parent glaciers, Reqiang and Jipucong decreased by 44.22% and 37.76%, respectively. The accelerating retreat of the glaciers not only reflects their generally negative mass balance but is consistent with the rapid expansion of the moraine-dammed lakes. When acted upon by external forces such as earthquakes, heavy rainfall, rapid melting of glaciers and dead ice, and snow/ice/rock avalanches, these lakes can become extremely dangerous, easily forming outburst mudslides, which can potentially spread to the Poiqu river basin and develop into cross-border (China and Nepal) GLOF disasters. Therefore, there is an urgent need to strengthen integrated risk management of glacial lake outburst disasters with multiple objectives and modes.

  18. Evolution and outburst risk analysis of moraine-dammed lakes in the central Chinese Himalaya

    Indian Academy of Sciences (India)

    Wang Shijin; Jiao Shitai

    2015-04-01

    The recent evolution and outburst risk of two typical moraine-dammed lakes, Galong and Gangxi, central Chinese Himalaya, are analyzed using topographic maps from 1974 and Landsat satellite imagery acquired in 1988, 2000 and 2014. The datasets show the areas of Galong and Gangxi lakes increasing at rates of 0.45 and 0.34 km2/year during the period 1974–2014, an expansion of 501% and 107%, respectively, in the past 41 years, while the areas of the parent glaciers, Reqiang and Jipucong decreased by 44.22% and 37.76%, respectively. The accelerating retreat of the glaciers not only reflects their generally negative mass balance but is consistent with the rapid expansion of the moraine-dammed lakes. When acted upon by external forces such as earthquakes, heavy rainfall, rapid melting of glaciers and dead ice, and snow/ice/rock avalanches, these lakes can become extremely dangerous, easily forming outburst mudslides, which can potentially spread to the Poiqu river basin and develop into cross-border (China and Nepal) GLOF disasters. Therefore, there is an urgent need to strengthen integrated risk management of glacial lake outburst disasters with multiple objectives and modes.

  19. Determination of heavy metal pollution in soils from selected potentially contaminated sites in Tema

    International Nuclear Information System (INIS)

    The objective of the study was to assess the concentration and determine the level of pollution by harmful heavy metals in soils from selected potentially contaminated sites in Tema. The metals of interest include; mercury, lead, cadmium, cobalt zinc, arsenic, nickel, copper and chromium. A total of forty seven (47) samples comprising thirty eight sub-samples (38) and nine (9) composite samples were collected from nine (9) different locations. These included playgrounds, steel processing factories, used Lead Acid Battery (ULAB) recycling plant, mechanic workshops and the municipal waste disposal site. The samples were prepared after which the elemental concentrations were determined using energy dispersive X-ray fluorescence (EDXRF) with a secondary target excitation arrangement (5.9 keV). The analysis of the samples yielded the following mean heavy metal concentrations in mg/kg: 424.38 (Cr); 408.68 (Ni); 14427 (Cu); 4129.87 (Zn); 1580.68 (As); 647.48 (Hg); 73361.51 (Pb) and 1176.16 (Co). The mean concentrations of heavy metals in the soils were in the following order Pb>Zn>As>Co>Cu>Hg>Cr>Ni. Mercury was detected at only two of the sites. The average heavy metals in the soils from the sites were generally high since most of them exceeded the optimum and action values of the New Dutch List. The Enrichment Factor (EF) ratios show that the enrichment of the elements in the soils ranged from deficiently to extremely highly enriched. The contamination factor show that the contamination by the heavy metals were low at some of the sites and very high at others. The geoaccumulation indices indicated that the playground (PG) has not been contaminated by any of the metals, C8 is contaminated strongly by mercury only and the contamination at the remaining sites varied from moderately contaminated to extremely contaminated by the metals. The Igeo also indicated that the elements accounting for extreme contamination are lead, arsenic, copper, zinc mercury and chromium. Lead accounted for the most contamination. The Pollution Load Index (PLI) rated Gravita as the mot contaminated of the sites and the Play ground the least contaminated. The pollution load indices indicated that two (2) out of the nine sites in the study were uncontaminated by the heavy metals (PLISS>WD>AFL>TS>L19>C8>PG. (au)

  20. Glacial Lake Outburst Flood Risk in the Poiqu/Bhote Koshi/Sun Koshi River Basin in the Central Himalayas

    Directory of Open Access Journals (Sweden)

    Narendra Raj Khanal

    2015-11-01

    Full Text Available The Himalayas have experienced several glacial lake outburst floods (GLOFs, and the risk of GLOFs is now increasing in the context of global warming. Poiqu watershed in the Tibet Autonomous Region, China, also known as the Bhote Koshi and Sun Koshi downstream in Nepal, has been identified as highly prone to GLOFs. This study explored the distribution of and changes in glacial lakes, past GLOFs and the resulting losses, risk from potential future GLOFs, and risk reduction initiatives within the watershed. A relationship was established between lake area and volume of lake water based on data from 33 lakes surveyed within the Hindu Kush Himalayan region, and the maximum possible discharge was estimated using this and other previously developed empirical equations. We recommend different strategies to reduce GLOF risk and highlight the need for a glacial lake monitoring and early-warning system. We also recommend strong regional cooperation, especially on issues related to transboundary rivers.

  1. Refrigeration Playbook: Natural Refrigerants; Selecting and Designing Energy-Efficient Commercial Refrigeration Systems That Use Low Global Warming Potential Refrigerants

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Caleb [CTA Architects Engineers, Boise, ID (United States); Reis, Chuck [CTA Architects Engineers, Boise, ID (United States); Nelson, Eric [CTA Architects Engineers, Boise, ID (United States); Armer, James [CTA Architects Engineers, Boise, ID (United States); Arthur, Rob [CTA Architects Engineers, Boise, ID (United States); Heath, Richard [CTA Architects Engineers, Boise, ID (United States); Rono, James [CTA Architects Engineers, Boise, ID (United States); Hirsch, Adam [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Doebber, Ian [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2015-03-01

    This report provides guidance for selecting and designing energy efficient commercial refrigeration systems using low global warming potential refrigerants. Refrigeration systems are generally the largest energy end use in a supermarket type building, often accounting for more than half of a building's energy consumption.

  2. Potential Mobility Among Career Teachers in New York City's Middle Schools: The Relationship Between Selected Occupational Characteristics, Expectations and Attitudes.

    Science.gov (United States)

    Castiglione, Lawrence V.

    To determine the relationship between selected occupational characteristics and attitudes of New York City middle-school teachers and their potential mobility within the system, a 33-item questionnaire was distributed to all teachers in a random sample of 12 junior high schools and four middle schools. The questionnaire was designed to obtain data…

  3. Plant operator selection system for evaluating employment candidates' potential for success in electric power plant operations positions

    International Nuclear Information System (INIS)

    The Plant Operator Selection System is a battery of tests and questionnaires that can be administered to job candidates in less than three hours. Various components of the battery measure what a job candidate has accomplished in previous educational and work situations, how well a candidate compares with others on a number of important aptitudes or abilities, and whether or not a candidate possesses the kind of personal stability required in power plant operations positions. A job candidate's answers to the tests and questionnaires of the Plant Operator Selection System are scored and converted to an OVERALL POTENTIAL INDEX. Values of the OVERALL POTENTIAL INDEX [OPI] range between 0 and 15. Candidates with high OPI values are much more likely to become effective and successful plant operators than candidates with low OPI values. It is possible to estimate the financial advantages to a company of using the Plant Operator Selection System in evaluating candidates for plant operations jobs

  4. Precipitation and snow cover in the Himalaya: from reanalysis to regional climate simulations

    Directory of Open Access Journals (Sweden)

    M. Ménégoz

    2013-10-01

    Full Text Available We applied a Regional Climate Model (RCM to simulate precipitation and snow cover over the Himalaya, between March 2000 and December 2002. Due to its higher resolution, our model simulates a more realistic spatial variability of wind and precipitation than those of the reanalysis of the European Centre of Medium range Weather Forecast (ECMWF used as lateral boundaries. In this region, we found very large discrepancies between the estimations of precipitation provided by reanalysis, rain gauges networks, satellite observations, and our RCM simulation. Our model clearly underestimates precipitation at the foothills of the Himalaya and in its eastern part. However, our simulation provides a first estimation of liquid and solid precipitation in high altitude areas, where satellite and rain gauge networks are not very reliable. During the two years of simulation, our model resembles the snow cover extent and duration quite accurately in these areas. Both snow accumulation and snow cover duration differ widely along the Himalaya: snowfall can occur during the whole year in western Himalaya, due to both summer monsoon and mid-latitude low pressure systems bringing moisture into this region. In Central Himalaya and on the Tibetan Plateau, a much more marked dry season occurs from October to March. Snow cover does not have a pronounced seasonal cycle in these regions, since it depends both on the quite variable duration of the monsoon and on the rare but possible occurrence of snowfall during the extra-monsoon period.

  5. Seismotectonics and crustal stress field in the Kumaon-Garhwal Himalaya

    Science.gov (United States)

    Mahesh, P.; Gupta, Sandeep; Saikia, Utpal; Rai, S. S.

    2015-08-01

    We present fault plane solutions of 94 well located small-to-moderate sized (1.5 ? ML ? 5.4) earthquakes, which occurred in the Kumaon-Garhwal Himalaya during 2005-2008, using P-wave polarity and body wave amplitudes. These earthquakes show a mixture of thrust, normal and strike-slip type mechanism, with a majority of thrust type. Most of the thrust earthquakes occur at a depth of 8-22 km in the Main Central Thrust (MCT) zone and the Lower Himalaya. The spatial distribution of these earthquakes suggest that the strain resulting from the ongoing collision of the Indian plate with the Eurasian plate is being consumed by thrust fault movement mainly on the north dipping Munsiari Thrust and south dipping Tons Thrust. The strike-slip earthquakes are mainly observed in the Lower Himalaya as well as around the Munsiari region in the MCT zone. The normal earthquakes are also observed in different parts of the Kumaon-Garhwal Himalaya and the Gangetic plain. Their occurrence is attributed to the local structure(s) as well as the flexure of the Indian plate. Stress tensor inversion of the calculated fault plane solutions indicates that the maximum compressive stress in the Gangetic plain is N-S directed and near vertical; whereas in the Kumaon-Garhwal Himalaya, it is near horizontal and NNE-SSW directed, and correlating with the prevailing stress condition due to northward movement of Indian plate.

  6. Depositional environment and provenance of Middle Siwalik sediments in Tista valley, Darjiling District, Eastern Himalaya, India

    Indian Academy of Sciences (India)

    Abhik Kundu; Abdul Matin; Malay Mukul

    2012-02-01

    The frontal part of the active, wedge-shaped Indo-Eurasian collision boundary is defined by the Himalayan fold-and-thrust belt whose foreland basin accumulated sediments that eventually became part of the thrust belt and is presently exposed as the sedimentary rocks of the Siwalik Group. The rocks of the Siwalik Group have been extensively studied in the western and Nepal Himalaya and have been divided into the Lower, Middle and Upper Subgroups. In the Darjiling–Sikkim Himalaya, the Upper Siwalik sequence is not exposed and the Middle Siwalik Subgroup exposed in the Tista river valley of Darjiling Himalaya preserves a ∼325 m thick sequence of sandstone, conglomerate and shale. The Middle Siwalik section has been repeated by a number of north dipping thrusts. The sedimentary facies and facies associations within the lithostratigraphic column of the Middle Siwalik rocks show temporal repetition of sedimentary facies associations suggesting oscillation between proximal-, mid- and distal fan setups within a palaeo-alluvial fan depositional environment similar to the depositional setup of the Siwalik sediments in other parts of the Himalaya. These oscillations are probably due to a combination of foreland-ward movement of Himalayan thrusts, climatic variations and mountain-ward shift of fanapex due to erosion. The Middle Siwalik sediments were derived from Higher- and Lesser Himalayan rocks. Mineral characteristics and modal analysis suggest that sedimentation occurred in humid climatic conditions similar to the moist humid climate of the present day Eastern Himalaya.

  7. Saving the Cryosphere in the Arctic and the Himalayas: Mitigation of Short Lived Climate Pollutants

    Science.gov (United States)

    Ramanathan, V.

    2012-12-01

    Observations reveal that the polar warming is hastened by the pole ward retreat of the extra-tropical storm track clouds and the sea-ice albedo feedback. The cloud systems associated with the storm tracks are the dominant radiative cooling cloud systems in the planet and their retreat adds more solar energy to the extra-tropical oceans. This is further amplified by the observed reduction in the arctic albedo due to the retreat of the sea-ice. Complicating this situation is the darkening of the arctic cryosphere by black carbon deposition. Over the Himalayas on the other hand, the thermo dynamical feedback involving water vapor amplifies surface warming over the elevated regions of Himalayas-Tibet by factors ranging from1 .5 to 2. This elevated warming is further amplified by black carbon in two distinctly different ways: First absorption of solar radiation in the atmosphere by black carbon has been shown to warm the layers above 5 km by as much as the warming due to CO2. Next, long range transport of black carbon, leads to deposition of black carbon over the bright snow and ice darkens them and enhances the absorption of intense tropical solar radiation over the Himalayas. After summarizing recent observations over the arctic and the Himalayas, we will show how mitigation of the four short lived climate pollutants (methane, black carbon, ozone and HFCs) can significantly slow down the arctic warming and the large warming observed over the elevated regions of the Himalayas-Tibet.

  8. Carbon allocation, sequestration and carbon dioxide mitigation under plantation forests of north western Himalaya, India

    Directory of Open Access Journals (Sweden)

    Bandana Devi

    2013-07-01

    Full Text Available The organic carbon and soils of the world comprise bulk of the terrestrial carbon and serve as amajorsink and source of atmospheric carbon. Increasing atmospheric concentrations of green house gases may be mitigated by increasing carbon sequestration in vegetation and soil. The study attempted to estimate biomass production and carbon sequestration potential of different plantation ecosystems in north western Himalaya, India. Biomass, carbon density of biomass, soil, detritus, carbon sequestration and CO2 mitigation potential were studied underdifferent plantation forest ecosystems comprising of eight different tree species viz. Quercus leucotrichophora, Pinus roxburghii, Acacia catechu, Acacia mollissima, Albizia procera, Alnus nitida, Eucalyptus tereticornis and Ulmus villosa. Above (185.57 ? 48.99 tha-1 and below ground (42.47 ? 10.38 tha-1 biomass was maximum in Ulmus villosa. The vegetation carbon density was maxium in Albizia procera (118.37 ? 1.49 tha-1 and minimum (36.50 ? 9.87 tha-1 in Acacia catechu. Soil carbon density was maximum (219.86? 10.34 tha-1 in Alnus nitida, and minimum (170.83? 20.60 tha-1in Pinus roxburghii. Detritus was higher in Pinus roxburghii (6.79 ? 2.0 tha-1. Carbon sequestration (7.91? 3.4 tha-1 and CO2 mitigation potential (29.09 ? 12.78 tha-1 was maximum in Ulmus villosa. Pearson correlation matrix revealed significant positive relationship of ecosystem carbon with plantation biomass, soil carbon and CO2 mitigation potential. With the emerging threat of climate change, such assessment of forest and soil carbon inventory would allow to devise best land management and policy decisions forsustainable management of fragile hilly ecosystem. 

  9. Carbon allocation, sequestration and carbon dioxide mitigation under plantation forests of north western Himalaya, India

    Directory of Open Access Journals (Sweden)

    Bandana Devi

    2013-05-01

    Full Text Available The organic carbon and soils of the world comprise bulk of the terrestrial carbon and serve as a major sink and source of atmospheric carbon. Increasing atmospheric concentrations of green house gases may be mitigated by increasing carbon sequestration in vegetation and soil. The study attempted to estimate biomass production and carbon sequestration potential of different plantation ecosystems in north western Himalaya, India. Biomass, carbon density of biomass, soil, detritus, carbon sequestration and CO2 mitigation potential were studied under different plantation forest ecosystems comprising of eight different tree species: Quercus leucotrichophora, Pinus roxburghii, Acacia catechu, Acacia mollissima, Albizia procera, Alnusnitida, Eucalyptus tereticornis and Ulmus villosa. Above (185.57±48.99tha-1 and below ground (42.47±10.38 tha-1 biomass was maximum in Ulmus villosa. The vegetation carbon density was maxium in Albizia procera(118.37±1.49 tha-1 and minimum (36.50±9.87 tha-1 in Acacia catechu. Soil carbon density was maximum (219.86±10.34 tha-1 in Alnus nitida, and minimum (170.83±20.60 tha-1 in Pinus roxburghii. Detritus was higher in Pinus roxburghii (6.79±2.0 tha-1. Carbon sequestration (7.91±3.4 tha-1 and CO2 mitigation potential (29.09±12.78 tha-1 was maximum in Ulmus villosa. Pearson correlation matrix revealed significant positive relationship of ecosystem carbon with plantation biomass, soil carbon and CO2 mitigation potential. With the emerging threat of climate change, such assessment of forest and soil carbon inventory would allow to devise best land management and policy decisions for sustainable management of fragile hilly ecosystem.

  10. Anthocyanin production as a potential visual selection marker during plant transformation

    OpenAIRE

    Kortstee, A.J.; Khan, S. A.; Helderman, C.M.; Trindade, L.M.; WU, Y.; Visser, R.G.F.; Brendolise, C.; Allan, A C; Schouten, H J; Jacobsen, E.

    2011-01-01

    A mutant allele of the transcription factor gene MYB10 from apple induces anthocyanin production throughout the plant. This gene, including its upstream promoter, gene coding region and terminator sequence, was introduced into apple, strawberry and potato plants to determine whether it could be used as a visible selectable marker for plant transformation as an alternative to chemically selectable markers, such as kanamycin resistance. After transformation, red coloured calli, red shoots and r...

  11. Alteraciones musculares en montañistas que ascendieron a Los Himalayas

    Scientific Electronic Library Online (English)

    SH, Torres; HJ, Finol; A, Brito; H, Rivera.

    2002-01-01

    Full Text Available El ascenso a los Montes Himalayas de un grupo de escaladores venezolanos permitió la obtención de muestras de músculo esquelético dos meses antes y un mes después de la expedición, con el objeto de estudiar los cambios producidos por la altura. Se tomó biopsia del músculo quadriceps femoris con la a [...] guja de Bergström en 5 sujetos dos meses antes, y en 4 sujetos un mes después de realizada la expedición. Las muestras fueron procesadas para estudio histoquímico con el objeto de clasificar los tipos de fibras musculares mediante la reacción de la adenosina trifosfatasa miofibrilar; los capilares se evidenciaron con la reacción de la a-amilasa-PAS. Además se estudió la ultraestructura con microscopía electrónica de transmisión. Se encontró que los sujetos cuyo músculo estaba en mejores condiciones alcanzaron la meta de 7.100 metros de altura. Estos sujetos presentaron posteriormente daño muscular segmentario marcado, en forma de atrofia muscular, daño capilar e infiltración de macrófagos. No hubo modificación en la proporción de los tipos de fibras. Se concluye que la actuación depende del estado previo del músculo y que la hipoxia, el esfuerzo muscular y el frío combinados, producen lesiones musculares segmentarias que persisten al menos por un mes. Abstract in english Skeletal muscle needle biopsies were obtained from quadriceps femoris muscle in five venezuelan climbers, two months before, and in four of the subjects, one month after an expedition to the Himalayas Mountains. In the samples, fibre types were determined by the miofibrillar adenosin triphosphatase [...] reaction, and capillaries were stained with the a-amylase-PAS reaction. Part of each sample was processed for ultrastructural study. The climbers performance was related to the previous state of the muscle. The three subjects that reached the goal of 7100 m altitude were those with normal of slightly altered muscles in the biopsy before the expedition. One month after the descent, muscle showed segmental alterations manifested as atrophy, capillary damage and infiltration of macrophages. No change was found in muscle fibre proportions. It is concluded that performance of the climbers depends on the previous state of skeletal muscle, and that the combined effect of altitude, exercise and cold produced segmental damage in skeletal muscle.

  12. Integration of Classification Tree Analyses and Spatial Metrics to Assess Changes in Supraglacial Lakes in the Karakoram Himalaya

    Science.gov (United States)

    Bulley, H. N.; Bishop, M. P.; Shroder, J. F.; Haritashya, U. K.

    2007-12-01

    Alpine glacier responses to climate chnage reveal increases in retreat with corresponding increases in production of glacier melt water and development of supraglacial lakes. The rate of occurrence and spatial extent of lakes in the Himalaya are difficult to determine because current spectral-based image analysis of glacier surfaces are limited through anisotropic reflectance and lack of high quality digital elevation models. Additionally, the limitations of multivariate classification algorithms to adequately segregate glacier features in satellite imagery have led to an increased interest in non-parametric methods, such as classification and regression trees. Our objectives are to demonstrate the utility of a semi-automated approach that integrates classification- tree-based image segmentation and object-oriented analysis to differentiate supraglacial lakes from glacier debris, ice cliffs, lateral and medial moraines. The classification-tree process involves a binary, recursive, partitioning non-parametric method that can account for non-linear relationships. We used 2002 and 2004 ASTER VNIR and SWIR imagery to assess the Baltoro Glacier in the Karakoram Himalaya. Other input variables include the normalized difference water index (NDWI), ratio images, Moran's I image, and fractal dimension. The classification tree was used to generate initial image segments and it was particularly effective in differentiating glacier features. The object-oriented analysis included the use of shape and spatial metrics to refine the classification-tree output. Classification-tree results show that NDWI is the most important single variable for characterizing the glacier-surface features, followed by NIR/IR ratio, IR band, and IR/Red ratio variables. Lake features extracted from both images show there were 142 lakes in 2002 as compared to 188 lakes in 2004. In general, there was a significant increase in planimetric area from 2002 to 2004, and we documented the formation of 46 new lakes. It appears that lake-size increments occur mostly in the lower part of the ablation zone, whereas most of the new lakes are formed in the upper part of the ablation zone. The classification-tree outputs are intuitive and the data-derived thresholds eliminate commonly subjective visual determination of threshold values. Semi-automated methods thus have the potential of eliminating laborious visual multi-temporal analysis of glacier-surface change, thereby producing consistent and replicable results needed to assess the trends of alpine-glacier response to climate change in the Himalaya.

  13. Forest resource use pattern in Kedarnath wildlife sanctuary and its fringe areas (a case study from Western Himalaya, India)

    International Nuclear Information System (INIS)

    The rural population of Himalaya has been strongly dependent on the forest resources for their livelihood for generations. The present study, carried out at three different altitudes of Kedarnath Wildlife Sanctuary (KWLS), explored forest resource-use patterns to understand rural peoples' dependency on the adjacent forests. A total of six forests were selected and the seven dependent villages were surveyed for the study of forest resource use patterns in relation to their socioeconomic status. Average fuelwood and fodder consumption were found to be 2.42 kg/capita/day and 43.96 kg/household/day respectively which was higher than the earlier reported values. Average fuelwood consumption by temporary dhaba (roadside refreshment establishments) owners (52.5 kg/dhaba/day) is much higher than the permanent villagers. Average cultivated land per family was less than 1 ha (0.56 ha). Inaccessibility of the area and deprived socio-economic status of the locals are largely responsible for the total dependency of the local inhabitants on nearby forests for fuelwood, fodder and other life supporting demands. Extensive farming of fuelwood trees on less used, barren land and establishment of fodder banks could be the alternative to bridge the gap between the demand and supply. Active participation of local people is mandatory for the conservation of these forests. - Highlights: • We studied energy consumption at different altitudes in Western Himalaya of India. • On an average, fuelwood and fodder consumption is 2.42 kg/capita/day and 43.96 kg/household/day respectively. • Maximum fuelwood (3.24 kg/capita/day) at higher and fodder consumption (1800 kg/household/day) at middle altitudes was recorded. • Dhabas (roadside refreshment establishments) consume much more fuelwood as compared to the permanent villagers (P<0.000, t-test). • Fuelwood consumption showed significant negative relationship with LPG (?0.87) and kerosene oil (?0.89)

  14. A comparative study of daytime-based methane emission from two wetlands of Nepal Himalaya

    Science.gov (United States)

    Zhu, Dan; Wu, Ning; Bhattarai, Nabin; Oli, Krishna Prasad; Tsering, Kuenzang; Rawat, Gopal Singh; Chen, Huai; Yang, Gang; He, Yinxin; Joshi, Srijana; Rana, Pradyumna; Ismail, Muhammad

    2015-04-01

    Natural wetlands constitute one of the major sources of methane emission to the atmosphere. Data on methane emission from wetlands on southern slopes of the Himalaya (SSH) have not been reported so far. Such data are very valuable for filling the gap and generating the whole emission patterns at regional or even global scale. We selected two wetlands at different altitudinal locations in Nepal, i.e. Beeshazar Lake (286 m a.s.l.) and Dhaap Lake (2089 m a.s.l.), to monitor the daytime methane emissions in monsoon season and dry season separately. Daytime methane emission varied between monsoon and dry seasons and also across different plant communities. The daytime methane emission variations were stronger in dry season than in monsoon season. The source/sink strengths of the two selected plant communities in each wetland were significantly different, presenting the strong spatial variation of methane emission within wetland. The methane emissions recorded in monsoon season were significantly higher (7.74 ± 6.49 mg CH4 m-2 h-1 and 1.00 ± 1.23 mg CH4 m-2 h-1 in low and high altitude wetlands, respectively) than those in dry season (1.84 ± 4.57 mg CH4 m-2 h-1 and 0.27 ± 0.71 mg CH4 m-2 h-1 in low and high altitude wetlands, respectively). Methane emissions from the low altitude wetland were significantly higher than those from the high altitude wetland in both of the seasons. Plant community height, standing water depth and soil temperature correlated to the methane emission from wetlands in this region.

  15. Ground state potential energy surfaces around selected atoms from resonant inelastic x-ray scattering

    Science.gov (United States)

    Schreck, Simon; Pietzsch, Annette; Kennedy, Brian; Såthe, Conny; Miedema, Piter S.; Techert, Simone; Strocov, Vladimir N.; Schmitt, Thorsten; Hennies, Franz; Rubensson, Jan-Erik; Föhlisch, Alexander

    2016-01-01

    Thermally driven chemistry as well as materials’ functionality are determined by the potential energy surface of a systems electronic ground state. This makes the potential energy surface a central and powerful concept in physics, chemistry and materials science. However, direct experimental access to the potential energy surface locally around atomic centers and to its long-range structure are lacking. Here we demonstrate how sub-natural linewidth resonant inelastic soft x-ray scattering at vibrational resolution is utilized to determine ground state potential energy surfaces locally and detect long-range changes of the potentials that are driven by local modifications. We show how the general concept is applicable not only to small isolated molecules such as O2 but also to strongly interacting systems such as the hydrogen bond network in liquid water. The weak perturbation to the potential energy surface through hydrogen bonding is observed as a trend towards softening of the ground state potential around the coordinating atom. The instrumental developments in high resolution resonant inelastic soft x-ray scattering are currently accelerating and will enable broad application of the presented approach. With this multidimensional potential energy surfaces that characterize collective phenomena such as (bio)molecular function or high-temperature superconductivity will become accessible in near future.

  16. Ethnobotanical uses of Biofencing Plants in Himachal Pradesh, Northwest Himalaya

    Directory of Open Access Journals (Sweden)

    Pankaj Sharma

    2013-01-01

    Full Text Available The aim of this study is to document the traditional knowledge on the utilization of Biofencing plants of Himachal Pradesh, Northwest Himalaya. The study was imperative because of dearth in the data pertaining to Biofencing plants in the study areas. The whole study area was stratified into three zones and a widespread field survey and random sampling method was adopted to assess the live fencing diversity of the region. The region occupies total 61 species. 10 (trees, 45 (shrubs, 4 (herbs and 2 were climbers. These belong to the 25 families. Rosaceae, Fabaceae, Berberidaceae, Elaeagnaceae and Euphorbiaceae are dominant families. Among genera, Berberis and Rosa are dominant. Of the total, 55 species are medicinally important and among these 20% are used for stomach disorders; 17% (skin complaints, 14% (asthma, 11% (fever and joint pains, 3% (aphrodisiac and snake bite, 1% (anticancerous and nerve disorders. Ethnobotanical assessment showed that 33 of the recorded species are used as fuel, 20 (edible, 8 (fodder and 4 (fiber and ornamental. This traditional knowledge of Biofencing plants contributes to the conservation of biodiversity and provides resource of economic and ecological interest and also decreasing the pressure on forests. So there is need to encourage the practice of using plant species for fencing in this region.

  17. Three hitherto unreported macro-fungi from Kashmir Himalaya

    International Nuclear Information System (INIS)

    The Himalayan state, Jammu and Kashmir due to its climate ranging from tropical deciduous forests to temperate and coniferous forests provides congenial habitat for the growth of diverse macro fungal species which in turn gives it the status of 'hub' of macro-fungal species. The macro fungal species richness of the state is directly related to its expansive forest communities and diverse weather patterns, but all the regions of the state have not been extensively surveyed till now. In this backdrop, a systematic survey for exploration and inventorization of macro fungal species of Western Kashmir Himalaya was undertaken during the year 2009 and 2010, which in turn resulted identification of the three species viz., Thelephora caryophyllea (Schaeff.) Pers., Coltricia cinnamomea (Pers.) Murr., and Guepinia helvelloides Fr. as new reports from the Kashmir. These species were identified on the basis of macro and microscopic characters and also the aid of taxonomic keys, field manuals, mushroom herbaria and help from expert taxonomists in the related field was taken into account. (author)

  18. Survey of radon and thoron in homes of Indian Himalaya.

    Science.gov (United States)

    Ramola, Rakesh Chand

    2011-07-01

    Measurements of radon, thoron and their progeny were carried out in some houses from Garhwal and Kumaun Himalayas of India using a LR-115 plastic track detector. The measurements were made in various residential houses of the area at a height of 2.5 m above the ground level using a twin chamber radon dosemeter, which can record the values of radon, thoron and their progeny separately. The concentrations of radon and thoron in these homes were found to vary from 11 to 191 and 1 to 156 Bq m(-3), respectively. The equilibrium factor between radon and progeny varies from 0.02 to 0.90, with an average of 0.26 for the region. The resulting dose rate due to radon, thoron and their decay products was found to vary from 0.02 to 0.84 ?Sv h(-1) with an arithmetic mean of 0.27 ?Sv h(-1). A detailed analysis of the distribution of radon, thoron and their decay products inside a house is also reported. The observed dose rates due to radon, thoron and progeny were found somewhat higher but well below the international recommendations. PMID:21486831

  19. Seismic slip deficit in the Kashmir Himalaya from GPS observations

    Science.gov (United States)

    Schiffman, Celia; Bali, Bikram Singh; Szeliga, Walter; Bilham, Roger

    2013-11-01

    measurements in Kashmir Himalaya reveal range-normal convergence of 11 ± 1 mm/yr with dextral shear of 5 ± 1 mm/yr. The transition from a fully locked 170 km wide décollement to the unrestrained descending Indian plate occurs at ~25 km depth over an ~23 km wide transition zone. The convergence rate is consistent with the lower bounds of geological estimates for the Main Frontal Thrust, Riasi, and Balapora fault systems, on which no surface slip has been reported in the past millennium. Of the 14 damaging Kashmir earthquakes since 1123, none may have exceeded Mw = 7.6. Therefore, either a seismic moment deficit equivalent to a Mw ? 8.7 earthquake exists or the historical earthquake magnitudes have been underestimated. Alternatively, these earthquakes have occurred on reverse faults in the Kashmir Valley, and the décollement has been recently inactive. Although this can reconcile the inferred and theoretical moment release, it is quantitatively inconsistent with observed fault slip in Kashmir.

  20. Tectonic evolution of Kashmir basin in northwest Himalayas

    Science.gov (United States)

    Alam, Akhtar; Ahmad, Shabir; Bhat, M. Sultan; Ahmad, Bashir

    2015-06-01

    Geomorphology has long been recognised as a key to evaluate the interplay between tectonics and landscape geometry in the regions of active deformation. We use geomorphic signatures at varied spatial scales interpreted from SRTM-DEM/Landsat-ETM data, supplemented with field observations to review the tectonic evolution of Kashmir basin in northwest Himalayas. Geomorphic evidence is persuasive of a credible NNW-SSE trending dextral strike-slip structure (central Kashmir Fault - CKF), with the strike length of ~ 165 km, stretched centrally over the NNW-SSE length of the Kashmir basin. As a result of the strike-slip motion and subsequent erosion, significant deformation has taken place along the CKF. In addition, broad geomorphic architecture of the basin reveals typical pull-apart characteristics. Hence, we deduce that the Kashmir basin has evolved as a pull-apart Quaternary sediment depression owing to the deformation along the central Kashmir Fault. The spatial distribution pattern of seismic events (NEIC-catalogue, 1973-2013) and GPS measurements (published), collectively substantiate our geomorphic interpretations.

  1. The mammalian fauna from the Central Himalaya, Nepal

    Directory of Open Access Journals (Sweden)

    Hem Bahadur Katuwal

    2013-07-01

    Full Text Available Nepal harbors unique mammalian fauna, but it is poorly studied at higher elevation. Mammalian fauna were recorded in Manaslu Conservation Area, Dudhkunda and Dudhkoshi valley of Solukhumbu district and Kanchenjunga Conservation Area of Nepal during March 2011 to April 2013 along the trail and the study plots from 700m to 4400m a.s.l. Semi-structured interviews were made with local people to understand their behavior and habitats. Altogether, 29 mammalian fauna were recorded. Five species were recorded new for the areas. Overall, Carnivore species (nine were encountered more, followed by species of the order Cetartiodactyla (seven. The highest number of mammalian fauna (18 was identified from Manaslu Conservation Area whereas the least (11 from Dudhkunda and Dudhkoshi valley. Human wildlife conflict was frequent with Himalayan Goral (Naemorhedus goral, Barking Deer (Muntiacus vaginalis, Himalayan Tahr (Hemitragus jemlahicus, Rhesus Macaque (Macaca mulatta, Nepal Grey Langur (Semnopithecus schistaceus and Himalayan Black Bear (Ursus thibetanus for crop depredation in these areas. Although mammalian research started a long time ago, scenario of comprehensive research is not satisfactory in the Central Himalaya, Nepal.

  2. Monsoon variability in the Himalayas under the condition of global warming

    International Nuclear Information System (INIS)

    An ice core-drilling program was carried out at the accumulation area of Dasuopu glacier (28deg23'N, 85deg43'E, 7100 m a.s.l.) in the central Himalayas in 1997. The ice core was analyzed continuously for stable isotopes (δ18O), and major ions throughout the core. Cycles indicated by δ18O, cations were identified and counted as seasonal fluctuations as annual increment from maximum to maximum values. Reconstructed 300-year annual net accumulation (water equivalent) from the core, with a good correlation to Indian monsoon, reflects a major precipitation trend in the central Himalayas. The accumulation trend, separated from the time series, shows a strong negative correlation to Northern Hemisphere temperature. Generally, as northern hemisphere temperature increases 0.1degC, the accumulation decreases about 80 mm, reflecting monsoon rainfall in the central Himalayas has decreased over the past decades in the condition of global warming. (author)

  3. Evaluation of oenological potential on clonal selections of cv. Cabernet Sauvignon from Chile

    Directory of Open Access Journals (Sweden)

    Ceppi de Lecco C.

    2014-01-01

    Full Text Available 13 clonal selections of cv Cabernet Sauvignon, established in Nancagua VI Region, Chile (34.39?°S?71.17?°W. The genetic identity of the vines was confirmed by ampelography and microsatellite markers (SSR. Evaluations in the 2012–2013 season include: performance, analytical and sensorial parameters on the wines made by microvinification. The results were statistically analyzed with the Statgraphics Plus program and multiple comparison test of Tukey at 95% confidence level. Sensorially, the wines were evaluated by a panel of 12 experts. The results were likewise analyzed by testing principal components (PCA with covariance matrix without rotation. In the season studied the selection 108 highlighted with a high yield (kg/plant, in the composition of the wine selections generally highlighted for contents of total polyphenols and anthocyanins over average. The results show typical sensory characteristics of wines from that grape variety, and it was possible to group the selections by their attributes (PCA with cherry red wines at different intensities, but without significant differences, with fruity and vegetal aromas, interesting complex flavors and with structured tannins.

  4. Survey on basic knowledge about exposure and potential environmental and health risks for selected nanomaterials

    DEFF Research Database (Denmark)

    Mikkelsen, Sonja Hagen; Hansen, Erik; Christensen, Trine Boe; Baun, Anders; Hansen, Steffen Foss; Binderup, Mona-Lise

    Based on a literature review this report provides a general description as well as an environmental and health profile of 7 nanomaterials. The examined nanomaterials are selected because of expected high use or specific environmental and health properties. Fullerenes, iron, silver, nanoclay and...... other nanomaterials were identified, there are areas where there may be reason for attention and thus need for more knowledge....

  5. Mexican rice borer (Lepidoptera: Crambidae) oviposition site selection stimuli on sugarcane, and potential field applications

    Science.gov (United States)

    The Mexican rice borer, Eoreuma loftini (Dyar), a key pest of sugarcane and rice in Texas that has recently invaded Louisiana, has not been successfully controlled using chemical insecticides or biological control agents. This greenhouse-based study examined selected sugarcane leaf characteristics,...

  6. Potential influence of selection criteria on the demographic composition of students in an Australian medical school

    Directory of Open Access Journals (Sweden)

    Puddey Ian B

    2011-11-01

    Full Text Available Abstract Background Prior to 1999 students entering our MBBS course were selected on academic performance alone. We have now evaluated the impact on the demographics of subsequent cohorts of our standard entry students (those entering directly from high school of the addition to the selection process of an aptitude test (UMAT, a highly structured interview and a rural incentive program. Methods Students entering from 1985 to 1998, selected on academic performance alone (N = 1402, were compared to those from 1999 to 2011, selected on the basis of a combination of academic performance, interview score, and UMAT score together with the progressive introduction of a rural special entry pathway (N = 1437. Results Males decreased from 57% to 45% of the cohort, students of NE or SE Asian origin decreased from 30% to 13%, students born in Oceania increased from 52% to 69%, students of rural origin from 5% to 21% and those from independent high schools from 56% to 66%. The proportion of students from high schools with relative socio-educational disadvantage remained unchanged at approximately 10%. The changes reflect in part increasing numbers of female and independent high school applicants and the increasing rural quota. However, they were also associated with higher interview scores in females vs males and lower interview scores in those of NE and SE Asian origin compared to those born in Oceania or the UK. Total UMAT scores were unrelated to gender or region of origin. Conclusions The revised selection processes had no impact on student representation from schools with relative socio-educational disadvantage. However, the introduction of special entry quotas for students of rural origin and a structured interview, but not an aptitude test, were associated with a change in gender balance and ethnicity of students in an Australian undergraduate MBBS course.

  7. Antioxidant potential of selected supplements in vitro and the problem of its extrapolation for in vivo

    OpenAIRE

    Julija Ogrin Papić; Borut Poljšak

    2012-01-01

    Introduction: antioxidants, free radicals and oxidative stress have been studied extensively for quite some time but their role in diseases and their prevention has not been clearly determined. Because commercialantioxidants do not need to pass clinical tests in order to be sold over the counter we have decided to test the antioxidant potential of different commercial preparations with the antioxidative properties.Methods: pH, rH and oxidant-reduction potential of different preparations in aq...

  8. Differentiating between rain, snow, and glacier contributions to river discharge in the western Himalaya using remote-sensing data and distributed hydrological modeling

    Science.gov (United States)

    Wulf, Hendrik; Bookhagen, Bodo; Scherler, Dirk

    2016-02-01

    Rivers draining the southern Himalaya provide most of the water supply for the densely populated Indo-Gangetic plains. Despite the importance of water resources in light of climate change, the relative contributions of rainfall, snow and glacier melt to discharge are not well understood, due to the scarcity of ground-based data in this complex terrain. Here, we quantify discharge sources in the Sutlej Valley, western Himalaya, from 2000 to 2012 with a distributed hydrological model that is based on daily, ground-calibrated remote-sensing observation. Based on the consistently good model performance, we analyzed the spatiotemporal distribution of hydrologic components and quantified their contribution to river discharge. Our results indicate that the Sutlej River's annual discharge at the mountain front is sourced to 55% by effective rainfall (rainfall reduced by evapotranspiration), 35% by snow melt and 10% by glacier melt. In the high-elevation orogenic interior glacial runoff contributes ?30% to annual river discharge. These glacier melt contributions are especially important during years with substantially reduced rainfall and snowmelt runoff, as during 2004, to compensate for low river discharge and ensure sustained water supply and hydropower generation. In 2004, discharge of the Sutlej River totaled only half the maximum annual discharge; with 17.3% being sourced by glacier melt. Our findings underscore the importance of calibrating remote-sensing data with ground-based data to constrain hydrological models with reasonable accuracy. For instance, we found that TRMM (Tropical Rainfall Measuring Mission) product 3B42 V7 systematically overestimates rainfall in arid regions of our study area by a factor of up to 5. By quantifying the spatiotemporal distribution of water resources we provide an important assessment of the potential impact of global warming on river discharge in the western Himalaya. Given the near-global coverage of the utilized remote-sensing datasets this hydrological modeling approach can be readily transferred to other data-sparse regions.

  9. Predicting paleoelevation of Tibet and the Himalaya from ? 18O vs. altitude gradients in meteoric water across the Nepal Himalaya

    Science.gov (United States)

    Garzione, Carmala N.; Quade, Jay; DeCelles, Peter G.; English, Nathan B.

    2000-11-01

    The ? 18O value of meteoric water varies with elevation, providing a means to reconstruct paleoelevation if the ? 18O values of paleowater are known. In this study, we determined the ? 18O values of water (? 18O mw) from small tributaries along the Seti River and Kali Gandaki in the Nepal Himalaya. We found that ? 18O mw values decrease with increasing altitude for both transects. ? 18O mw vs. altitude along the Kali Gandaki in west-central Nepal fit a second order polynomial curve, consistent with increasing depletion of 18O with increasing elevation, as predicted by a Rayleigh-type fractionation process. This modern ? 18O mw vs. altitude relationship can be used to constrain paleoelevation from the ? 18O values of Miocene-Pliocene carbonate (? 18O c) deposited in the Thakkhola graben in the southern Tibetan Plateau. Paleoelevations of 3800±480 m to 5900±350 are predicted for the older Tetang Formation and 4500±430 m to 6300±330 m for the younger Thakkhola Formation. These paleoelevation estimates suggest that by ˜11 Ma the southern Tibetan Plateau was at a similar elevation to modern.

  10. Host Selection of Potential West Nile Virus Vectors in Puerto Barrios, Guatemala, 2007

    Science.gov (United States)

    Kading, Rebekah C.; Reiche, Ana Silvia Gonzalez; Morales-Betoulle, Maria Eugenia; Komar, Nicholas

    2013-01-01

    The selection of vertebrate hosts by Culex mosquitoes relative to West Nile virus (WNV) transmission in neotropical countries such as Guatemala is not described. This study determined the feeding patterns of Cx. quinquefasciatus and Cx. nigripalpus and estimated the relative contribution of two common and frequently infected wild bird species, Turdus grayi and Quiscalus mexicanus, to WNV transmission. Engorged mosquitoes were collected from rural and urban habitats after the dry and wet seasons in the Department of Izabal in 2007. Host selection by Cx. nigripalpus varied significantly between urban and rural habitats. Both Cx. quinquefasciatus and Cx. nigripalpus fed predominantly on chickens and other domestic animals. Blood meals from wild birds were rare, accounting for 1.1% of blood meals identified from Cx. quinquefasciatus and 6.5% of blood meals from Cx. nigripalpus. Transmission of WNV by these two mosquito species may be dampened by extensive feeding on reservoir-incompetent hosts. PMID:23208881

  11. Therapeutic potential of functional selectivity in the treatment of heart failure

    DEFF Research Database (Denmark)

    Christensen, Gitte Lund; Aplin, Mark; Hansen, Jakob Lerche

    2010-01-01

    Adrenergic and angiotensin receptors are prominent targets in pharmacological alleviation of cardiac remodeling and heart failure, but their use is associated with cardiodepressant side effects. Recent advances in our understanding of seven transmembrane receptor signaling show that it is possible to design ligands with "functional selectivity," acting as agonists on certain signaling pathways while antagonizing others. This represents a major pharmaceutical opportunity to separate desired from ...

  12. Beyond EICA : understanding post-establishment evolution requires a broader evaluation of potential selection pressures

    OpenAIRE

    Joshua Atwood; Laura Meyerson

    2011-01-01

    Research on post-establishment evolution in nonnative plant populations has focused almost exclusively on testing the Evolution of Increased Competitive Ability (EICA) hypothesis, which posits that the lack of specialized herbivores in the invaded range drives evolution in nonnative plant populations. Fifteen years of conflicting EICA test results suggest that selection pressures other than specialized herbivory are important in driving post-establishment evolution in invasive species. Altern...

  13. Maternal use of selective serotonin reuptake inhibitors and risk of miscarriage - assessing potential biases

    DEFF Research Database (Denmark)

    Johansen, Rie Laurine Rosenthal; Mortensen, Laust Hvas; Andersen, Anne-Marie Nybo; Hansen, Anne Vinkel; Strandberg-Larsen, Katrine

    2015-01-01

    BACKGROUND: The use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy has been associated with miscarriage, but the association may be biased by maternal mental illness, lifestyle and exposure misclassification. METHODS: A register study on all pregnancies in Denmark between 1996 and 2009 was conducted using individualised data from the Danish National Patient Register, the Medical Birth Register, the Danish Psychiatric Central Register, the Danish National Prescription databas...

  14. Potential of Selective Estrogen Receptor Modulators as Treatments and Preventives of Breast Cancer

    OpenAIRE

    PENG, JING; Sengupta, Surojeet; Jordan, V. Craig

    2009-01-01

    Estrogen plays vital roles in human health and diseases. Estrogen mediates its actions almost entirely by binding to estrogen receptors (ER), alpha and beta which further function as transcription factors. Selective estrogen receptor modulators (SERMs) are synthetic molecules which bind to ER and can modulate its transcriptional capabilities in different ways in diverse estrogen target tissues. Tamoxifen, the prototypical SERM, is extensively used for targeted therapy of ER positive breast ca...

  15. Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies

    DEFF Research Database (Denmark)

    Bennacef, Idriss; Salinas, Cristian A

    2009-01-01

    Compound 1 is a potent and selective antagonist of the dopamine D(3) receptor. With the aim of developing a carbon-11 labeled ligand for the dopamine D(3) receptor, 1 was selected as a potential PET probe. [(11)C]1 was obtained by palladium catalyzed cross coupling using [(11)C]cyanide and 4 with a specific activity of 55.5+/-25.9GBq/micromol (1.5+/-0.7Ci/micromol). [(11)C]1 was tested in porcine and non-human primate models to assess its potential as a radioligand for PET imaging of the dopamine D(3) receptor. We conclude that in both species and despite appropriate in vitro properties, [(11)C]1 does not show any specific signal for the dopamine D(3) receptor.

  16. Potential Selective Responding in a Parent Questionnaire Study of Post-Institutionalized Children.

    Science.gov (United States)

    Hawk, Brandi N; Wright, Amanda; Julian, Megan M; Rosas, Johana M; Merz, Emily C; McCall, Robert B

    2013-01-01

    Selective responding bias, though under-researched, is of particular concern in the study of post-institutionalized children because many studies rely on mailed questionnaires and response rates are often low. The current study addresses the impact of selective responding in a single wave of data collection and in a multi-wave study. Participants were 121 parents from a larger four-wave study of post-institutionalized children, identified as Never Responders, Previous Responders (but not to the current wave), or Wave 4 Responders. Parents were telephoned and asked about their adopted child's family, school, peer, and behavioral adjustment. The children (47% male) ranged in age from 2 to 20 years (M = 10.79, SD = 4.59) and had been adopted between 5 and 54 months of age (M = 15.49, SD = 9.94). There were no differences in parent ratings of adjustment for a single wave of data collection; however, participants who never responded reported poorer family and peer adjustment than those who had responded to at least one wave of data collection. Within a single wave of data collection, there was no evidence that selective responding contributes much bias. Over a multi-wave study, however, results may under-represent adjustment difficulties, especially with family and friends. PMID:23710124

  17. Canola Cake as a Potential Substrate for Proteolytic Enzymes Production by a Selected Strain of Aspergillus oryzae: Selection of Process Conditions and Product Characterization.

    Science.gov (United States)

    Freitas, Adriana C; Castro, Ruann J S; Fontenele, Maria A; Egito, Antonio S; Farinas, Cristiane S; Pinto, Gustavo A S

    2013-12-25

    Oil cakes have excellent nutritional value and offer considerable potential for use in biotechnological processes that employ solid-state fermentation (SSF) for the production of high value products. This work evaluates the feasibility of using canola cake as a substrate for protease production by a selected strain of Aspergillus oryzae cultivated under SSF. The influences of the following process parameters were considered: initial substrate moisture content, incubation temperature, inoculum size, and pH of the buffer used for protease extraction and activity analysis. Maximum protease activity was obtained after cultivating Aspergillus oryzae CCBP 001 at 20°C, using an inoculum size of 10(7)?spores/g in canola cake medium moistened with 40?mL of water to 100?g of cake. Cultivation and extraction under selected conditions increased protease activity 5.8-fold, compared to the initial conditions. Zymogram analysis of the enzymatic extract showed that the protease molecular weights varied between 31 and 200?kDa. The concentrated protease extract induced clotting of casein in 5?min. The results demonstrate the potential application of canola cake for protease production under SSF and contribute to the technological advances needed to increase the efficiency of processes designed to add value to agroindustrial wastes. PMID:24455400

  18. Canola Cake as a Potential Substrate for Proteolytic Enzymes Production by a Selected Strain of Aspergillus oryzae: Selection of Process Conditions and Product Characterization

    Science.gov (United States)

    Freitas, Adriana C.; Castro, Ruann J. S.; Fontenele, Maria A.; Egito, Antonio S.; Farinas, Cristiane S.; Pinto, Gustavo A. S.

    2013-01-01

    Oil cakes have excellent nutritional value and offer considerable potential for use in biotechnological processes that employ solid-state fermentation (SSF) for the production of high value products. This work evaluates the feasibility of using canola cake as a substrate for protease production by a selected strain of Aspergillus oryzae cultivated under SSF. The influences of the following process parameters were considered: initial substrate moisture content, incubation temperature, inoculum size, and pH of the buffer used for protease extraction and activity analysis. Maximum protease activity was obtained after cultivating Aspergillus oryzae CCBP 001 at 20°C, using an inoculum size of 107?spores/g in canola cake medium moistened with 40?mL of water to 100?g of cake. Cultivation and extraction under selected conditions increased protease activity 5.8-fold, compared to the initial conditions. Zymogram analysis of the enzymatic extract showed that the protease molecular weights varied between 31 and 200?kDa. The concentrated protease extract induced clotting of casein in 5?min. The results demonstrate the potential application of canola cake for protease production under SSF and contribute to the technological advances needed to increase the efficiency of processes designed to add value to agroindustrial wastes. PMID:24455400

  19. Bone-sparing and anti-inflammatory potential of the novel selective glucocorticoid receptor modulator, compound A

    OpenAIRE

    Thiele, Sylvia

    2013-01-01

    Rheumatoid arthritis (RA) is a common chronic inflammatory disease that affects about 1% of the Western population. Glucocorticoids (GC) are widely used for the treatment of RA and other immune-mediated diseases, such as asthma, but their use is associated with adverse effects on bone metabolism. Because of that, new selective GC receptor (GR) agonists (SEGRAs) with the potential for an improved risk/benefit profile have been developed. Compound A (CpdA) is a novel SEGRA, which showed an impr...

  20. Interactions of biotic and abiotic environmental factors in an ectomycorrhizal symbiosis, and the potential for selection mosaics

    Directory of Open Access Journals (Sweden)

    Hoeksema Jason D

    2008-05-01

    Full Text Available Abstract Background Geographic selection mosaics, in which species exert different evolutionary impacts on each other in different environments, may drive diversification in coevolving species. We studied the potential for geographic selection mosaics in plant-mycorrhizal interactions by testing whether the interaction between bishop pine (Pinus muricata D. Don and one of its common ectomycorrhizal fungi (Rhizopogon occidentalis Zeller and Dodge varies in outcome, when different combinations of plant and fungal genotypes are tested under a range of different abiotic and biotic conditions. Results We used a 2 × 2 × 2 × 2 factorial experiment to test the main and interactive effects of plant lineage (two maternal seed families, fungal lineage (two spore collections, soil type (lab mix or field soil, and non-mycorrhizal microbes (with or without on the performance of plants and fungi. Ecological outcomes, as assessed by plant and fungal performance, varied widely across experimental environments, including interactions between plant or fungal lineages and soil environmental factors. Conclusion These results show the potential for selection mosaics in plant-mycorrhizal interactions, and indicate that these interactions are likely to coevolve in different ways in different environments, even when initially the genotypes of the interacting species are the same across all environments. Hence, selection mosaics may be equally as effective as genetic differences among populations in driving divergent coevolution among populations of interacting species.

  1. Free ion selective radionuclide extraction (FISRE) and the targeting potential of theranostic radio-complexes

    International Nuclear Information System (INIS)

    The present paper briefly discusses molecular targeting, receptors, and distribution, all set in the context of the use of radiolabelled and chelated peptides in peptide receptor scintigraphy (PRS) and peptide radionuclide therapy (PRRT). The discussion further addresses the potential of compartmental modelling as a tool in optimization approaches for targeting complexes. The latter point is illustrated by the use of FISRE-methods and clinical data on 177Lu-DOTA-Tyr3-octreotate in a preliminary modelling trial, to show the principal relevance of various complex properties for targeting characteristics in optimization exercises. The results indicate that improving the complex dynamic stability may mimic improved complex targeting potential. (author)

  2. YIELD POTENTIAL OF SELECTED MEDICINAL HERBS AT THREE PLANT SPACINGS IN NEW MEXICO

    Science.gov (United States)

    Field studies were conducted to determine the production potential of echinacea (Echinacea purpurea), valerian (Valeriana officinalis), mullein (Verbascum thapsus) and yerba mansa (Anemopsis californica) medicinal herbs at two sites in New Mexico. Las Cruces, N.M. is at an elevation of 1,186 m and h...

  3. FAMACHA©: A potential tool for targeted selective treatment of chronic fasciolosis in sheep.

    Science.gov (United States)

    Olah, Sophie; van Wyk, Jan A; Wall, Richard; Morgan, Eric R

    2015-09-15

    The liver fluke Fasciola hepatica causes considerable damage to the health, welfare and productivity of ruminants in temperate areas, and its control is challenged by anthelmintic resistance. Targeted selective treatment (TST) is an increasingly established strategy for preserving anthelmintic efficacy in grazing livestock, yet no practical indicators are available to target individuals for treatment against fluke infection. This paper evaluates the FAMACHA(©) system, a colour chart for the non-invasive detection of anaemia in small ruminants, for this purpose. FAMACHA(©) scores were collected from 288 sheep prior to slaughter during the winter period, when fluke infections were largely mature, and condemned livers were recovered and adult flukes extracted. Average FAMACHA(©) score was significantly higher (=paler conjunctivae) in animals whose livers were condemned (3.6, n=62) than in those whose livers were not condemned (2.1). The number of adult flukes recovered ranged from 2 to 485, and was positively correlated with FAMACHA(©) score (r(2)=0.54, p<0.001). Packed cell volume was correlated negatively with both FAMACHA(©) score (n=240, r=0.23, p<0.001) and fluke number (r=0.24, p<0.001). Nematode faecal egg count (FEC) did not correlate with FAMACHA(©) score, and selective treatment of individual sheep with FAMACHA(©) scores above 2 or 3 would have preserved between 27 and 100% of nematodes in refugia on the basis of FEC, depending on group and the threshold used for treatment. FAMACHA(©) holds promise as a tool for selective treatment of sheep against adult F. hepatica, in support of refugia-based control of fluke and nematode infections, and further field evaluation is warranted. PMID:26223154

  4. Disease burden of fuelwood combustion pollutants in rural households of the Himalayas, India

    Directory of Open Access Journals (Sweden)

    Rajiv Pandey

    2012-03-01

    Full Text Available

    Background: household biomass combustion for cooking purposes produces pollutants. Exposure to these pollutants has various adverse health impacts and is a major contributor to global disease burden. However, a precise estimate of the burden attributable to biomass combustion at the local level is not available in different parts of the world, therefore restricting policymakers’ ability to develop targeted actions against the health hazards. a study was conducted in the rural Himalayas to generate information about disease burden, with the purpose of aiding the development of strategies to improve public health.
    Methods: exposure level, population exposed and other relevant data regarding fuel-wood use, were collected through questionnaire survey from 102 randomly selected households spread in 46 villages in a two phase cluster random sampling design study during 2008 – 09. the burden of disease for acute Lower respiratory Infection (aLrI, chronic obstructive Pulmonary disease (coPd and Lung cancer were estimated as per fuel-based approach of WHo guidelines for rural hilly households, using fuel- wood for cooking.
    Results: households, primarily dependent on fuel-wood for fuel, had disability adjusted life years (daLYs lost and deaths that were much higher than the national status. The incidence of disease burden was 2 909 daLYs lost, with a share of 1 987 for aLrI in children "up to" 5 years age, 730 for coPd and 192 for Lung cancer in adults more than 30 years old, respectively.
    This result has implications for policy makers when deciding on an effective exposure reduction strategy and describes the risks connected between these health hazards and the health outcome of inhabitants exposed to them. The paper also discusses the intervention strategies for “addressing” the issues relevant to fuel-wood generated exposure.

  5. Genetic diversity of selected genes that are potentially economically important in feral sheep of New Zealand

    OpenAIRE

    Sedcole J Richard; Forrest Rachel H; Merrick Norma; Fang Qian; Zhou Huitong; Abbott Johanna; McKenzie Grant W; Hickford Jonathan G

    2010-01-01

    Abstract Background Feral sheep are considered to be a source of genetic variation that has been lost from their domestic counterparts through selection. Methods This study investigates variation in the genes KRTAP1-1, KRT33, ADRB3 and DQA2 in Merino-like feral sheep populations from New Zealand and its offshore islands. These genes have previously been shown to influence wool, lamb survival and animal health. Results All the genes were polymorphic, but no new allele was identified in the fer...

  6. Genetic diversity of selected genes that are potentially economically important in feral sheep of New Zealand

    Directory of Open Access Journals (Sweden)

    Sedcole J Richard

    2010-12-01

    Full Text Available Abstract Background Feral sheep are considered to be a source of genetic variation that has been lost from their domestic counterparts through selection. Methods This study investigates variation in the genes KRTAP1-1, KRT33, ADRB3 and DQA2 in Merino-like feral sheep populations from New Zealand and its offshore islands. These genes have previously been shown to influence wool, lamb survival and animal health. Results All the genes were polymorphic, but no new allele was identified in the feral populations. In some of these populations, allele frequencies differed from those observed in commercial Merino sheep and other breeds found in New Zealand. Heterozygosity levels were comparable to those observed in other studies on feral sheep. Our results suggest that some of the feral populations may have been either inbred or outbred over the duration of their apparent isolation. Conclusion The variation described here allows us to draw some conclusions about the likely genetic origin of the populations and selective pressures that may have acted upon them, but they do not appear to be a source of new genetic material, at least for these four genes.

  7. Potential of Mean Force Calculations for Ion Selectivity in a Cyclic Peptide Nanotube

    International Nuclear Information System (INIS)

    Ion selectivity in a simple cyclic peptide nanotube, composed of four cyclo[-(D-Ala-Glu-D-Ala-Gln)2-] units, is investigated by calculating the PMF profiles of Na+, K+, and Cl. ions permeating through the peptide nanotube in water. The final PMF profiles of the ions obtained from the umbrella sampling (US) method show an excellent agreement with those from the thermodynamic integration (TI) method. The PMF profiles of Na+ and K+ display free energy wells while the PMF curve of Cl- features free energy barriers, indicating the selectivity of the cyclic peptide nanotube to cations. Decomposition of the total mean force into the contribution from each component in the system is also accomplished by using the TI method. The mean force decomposition profiles of Na+ and K+ demonstrate that the dehydration free energy barriers by water molecules near the channel entrance and inside the channel are completely compensated for by attractive electrostatic interactions between the cations and carbonyl oxygens in the nanotube. In the case of Cl-, the dehydration free energy barriers are not eliminated by an interaction between the anion and the peptide nanotube, leading to the high free energy barriers in the PMF profile. Calculations of the coordination numbers of the ions with oxygen atoms pertaining to either water molecules or carbonyl groups in the peptide nanotube reveal that the stabilization of the cations in the midplane regions of the nanotube arises from the favorable interaction of the cations with the negatively charged carbonyl oxygens

  8. Fluoxetine potentiation of methylphenidate-induced neuropeptide expression in the striatum occurs selectively in direct pathway (striatonigral) neurons.

    Science.gov (United States)

    Van Waes, Vincent; Carr, Betsy; Beverley, Joel A; Steiner, Heinz

    2012-09-01

    Concomitant therapies combining psychostimulants such as methylphenidate and selective serotonin reuptake inhibitors (SSRIs) are used to treat several mental disorders, including attention-deficit hyperactivity disorder/depression comorbidity. The neurobiological consequences of these drug combinations are poorly understood. Methylphenidate alone induces gene regulation that mimics partly effects of cocaine, consistent with some addiction liability. We previously showed that the SSRI fluoxetine potentiates methylphenidate-induced gene regulation in the striatum. The present study investigated which striatal output pathways are affected by the methylphenidate + fluoxetine combination, by assessing effects on pathway-specific neuropeptide markers. Results demonstrate that fluoxetine (5 mg/kg) potentiates methylphenidate (5 mg/kg)-induced expression of substance P and dynorphin, markers for direct pathway neurons. In contrast, no drug effects on the indirect pathway marker enkephalin were found. Because methylphenidate alone has minimal effects on dynorphin, the potentiation of dynorphin induction represents a more cocaine-like effect for the drug combination. On the other hand, the lack of an effect on enkephalin suggests a greater selectivity for the direct pathway compared with psychostimulants such as cocaine. Overall, the fluoxetine potentiation of gene regulation by methylphenidate occurs preferentially in sensorimotor striatal circuits, similar to other addictive psychostimulants. These results suggest that SSRIs may enhance the addiction liability of methylphenidate. PMID:22738672

  9. Treeline dynamics with climate change at Central Nepal Himalaya

    Science.gov (United States)

    Gaire, N. P.; Koirala, M.; Bhuju, D. R.; Borgaonkar, H. P.

    2013-10-01

    Global climate change has multidimensional impacts with several biological fingerprints, and treeline shifting in tandem with climate change is a widely observed phenomenon in various parts of the world. In Nepal several impacts of climate change on physical environments have been observed. However, studies on the biological impacts are lacking. This dendrochronological study was carried out at the treeline ecotone (3750-4003 m a.s.l.) in the Kalchuman Lake (Kal Tal) area of the Manaslu Conservation Area in central Nepal Himalaya with the aim to study the dynamic impact of climate change at the treeline. The study provides an insight into regeneration and treeline dynamics over the past 200 yr. Two belt transect plots (size: 20 m wide, >250 m long) were laid covering forest line, treeline as well as tree species Abies spectabilis and Betula utilis was done and their tree-cores were collected. Stand character and age distribution revealed an occurrence of more matured B. utilis (max. age 198 yr old) compared to A. spectabilis (max. age 160 yr). A. spectabilis contained an overwhelmingly high population (89%) of younger plants (climate change and much wider differences anticipated in their population status as climate continues to cha spectabilis correlated negatively with the mean monthly temperature of May-August of the current year and with September of the previous year. The regeneration of A. spectabilis, on the other hand, was positively related with May-August precipitation and January-April temperature of the current year. The reconstructed average summer temperature (May-August) using tree ring data revealed alternate period of cool and warm period with warming in the 2nd half of the 20th century. Further palynological and geochronological studies of sediments of the Kalchuman Lake would advance our understanding of past climatic trends and dynamics of the associated treeline and vegetation in the area.

  10. Distribution of the Late-Quaternary deformation in Northwestern Himalaya

    Science.gov (United States)

    Vassallo, R.; Mugnier, J.-L.; Vignon, V.; Malik, M. A.; Jayangondaperumal, R.; Srivastava, P.; Jouanne, F.; Carcaillet, J.

    2015-02-01

    Three main Cenozoic thrusts at the front of Northwestern Himalaya have accommodated most of the India-Eurasia convergence across the belt over the last million years and produced the present relief. Their recent tectonic activity is poorly known because of the long period of inaccessibility of the Jammu and Kashmir state, and because the latest and only large earthquake recorded in the region occurred in 1555 AD. We show where the deformation is localized during the Late-Quaternary, and determine shortening rates across the structures by analyzing the geometry and chronology of geomorphic markers. The Main Boundary Thrust in this region ceased moving at least ?30 ka ago. On the contrary, the more external Medlicott-Wadia Thrust and Main Frontal Thrust, both merging at depth on the sub-flat detachment of the Main Himalayan Thrust, exhibit hectometric-scale deformations accumulated during the last thousands of years. The total shortening rate absorbed by these faults over the last 14-24 ka is between 13.2 and 27.2 mm/yr (11.2 ± 3.8 and 9.0 ± 3.2 mm /yr, respectively). Part of this deformation may be associated to the geometry of the Chenab reentrant, which could generate an extra oblique component. However, the lower bound of our shortening rates is consistent with previously determined geodetic rates. Active deformation on these structures follows an in-sequence/out-of-sequence pattern, with breaking of both ramps being possible for earthquakes triggered on the main detachment.

  11. Phytochemical diversity of Murraya koenigii (L.) Spreng. from Western Himalaya.

    Science.gov (United States)

    Verma, Ram S; Chauhan, Amit; Padalia, Rajendra C; Jat, Sanjeev K; Thul, Sanjog; Sundaresan, Velusamy

    2013-04-01

    Murraya koenigii (L.) Spreng. (Rutaceae), commonly known as 'curry leaf tree', is a popular spice and condiment of India. To explore the diversity of the essential-oil yield and aroma profile of curry leaf, growing wild in foot and mid hills of north India, 58 populations were collected during spring season. M. koenigii populations were found to grow up to an altitude of 1487?m in north India. Comparative results showed considerable variations in the essential-oil yield and composition. The essential-oil yield varied from 0.14 to 0.80% in shade-dried leaves of different populations of M. koenigii. Analysis of the essential oils by GC and GC/MS, and the subsequent classification by statistical analysis resulted in four clusters with significant variations in their terpenoid composition. Major components of the essential oils of investigated populations were ?-pinene (2; 4.5-71.5%), sabinene (3; <0.05-66.1%), (E)-caryophyllene (11; 1.6-18.0%), ?-pinene (4; <0.05-13.6%), terpinen-4-ol (9; 0.0-8.4%), ?-terpinene (8; 0.2-7.4%), limonene (7; 1.1-5.5%), ?-terpinene (6; 0.0-4.5%), (E)-nerolidol (14; 0.0-4.1%), ?-humulene (12; 0.6-3.5%), ?-thujene (1; 0.0-2.5%), ?-elemene (10; 0.2-2.4%), ?-selinene (13; 0.2-2.3%), and myrcene (5; 0.5-2.1%). Comparison of the present results with those in earlier reports revealed new chemotypes of M. koenigii in investigated populations from Western Himalaya. The present study documents M. koenigii populations having higher amounts of sabinene (3; up to 66.1%) for the first time. PMID:23576349

  12. Global Warming, Climate Change and Glacier Retreat of Nepal Himalayas

    Science.gov (United States)

    Shrestha, S.; Hisaki, Y.

    2007-12-01

    Global average air temperature near the earth surface rose 0.74¡¾0.18¨¬C during the twentieth century. The Intergovernmental Panel on Climate Change (IPCC) concludes that observed increased globally averaged temperatures since mid-twentieth century is very likely due to the observed increment in anthropogenic greenhouse gas concentrations, which leads to warming of the surface and lower atmosphere by increasing the greenhouse effect. Climate models referred by IPCC project that global surface temperature are likely to be increase by 1.1 to 6.4¨¬C between 1990 and 2100. An increase in global temperature is expected to cause other changes including glacier retreat, sea level rise, increase intensity of extreme weather events and change in the pattern of precipitation, etc. The Nepal Himalaya revealed 3,252 glaciers and 2,323 lakes, which are 3,500 m above the sea level. They cover an area of 5,323 km2 with an estimated ice reserve of 481 km3. The average temperature in Nepal is rising by 0.5¨¬C per decade, and because of this reason, big glacial lakes in the country are at high risk of flooding from glacial lake bursts, which would have an adverse effect, such as huge loss of life and property. Nepal is facing a disturbance in mountain climate, flash floods, cloudbursts, erratic weather patterns and so on. The death of number of people due to floods and landslides is increasing annually. It is reported that more than 164 people already died because of floods and landslides during the current year, 2007 rainy season. Nepal does emit negligible greenhouse gases compare to developed and industrialized countries, however, country and people are facing the consequences of actions of other developed and industrialized countries. Study shows the¡¡disasters in current years and possible hazards in future due to the probable causes of global warming and recommends some suggestions for controlling of green house gases emission.

  13. Potential of selected lactic acid bacteria to produce food compatible antifungal metabolites.

    Science.gov (United States)

    De Muynck, Cassandra; Leroy, Annelies I J; De Maeseneire, Sofie; Arnaut, Filip; Soetaert, Wim; Vandamme, Erick J

    2004-01-01

    The aim of this study was to assess the potential of lactic acid bacteria to inhibit the outgrowth of some common food-spoiling fungi. Culture supernatants of 17 Lactic acid bacterial strains as well as of three commercial probiotic cultures were evaluated for antifungal activity using an agar-diffusion method. The method parameters were chosen in order to reveal compounds for potential use in food (bio)preservation. Thirteen strains showed antifungal activity of which five strains were very promising: Lactobacillus acidophilus LMG 9433, L. amylovorus DSM 20532, L. brevis LMG 6906, L. coryniformis subsp. coryniformis LMG 9196 and L. plantarum LMG 6907. Four of these five strains were further examined; it was found that the produced antifungal metabolites were pH-dependent. The exact chemical nature of these substances has not been revealed yet. PMID:15646380

  14. Active prey selection in two pelagic copepods feeding on potentially toxic and non-toxic dinoflagellates

    DEFF Research Database (Denmark)

    Schultz, Mette; Kiørboe, Thomas

    2009-01-01

    Grazing on two red tide dinoflagellates, the potentially toxic Karenia mikimotoi and the non-toxic Gyrodinium instriatum, was examined in two species of marine copepods, Pseudocalanus elongatus and Temora longicornis. Both copepods cleared K. mikimotoi at rates that were a little lower but comparable to those at which they cleared the slightly larger G. instriatum when the two dinoflagellates were offered separately. However, when feeding on mixtures of the two prey species, the clearance rates ...

  15. Psychopathy-Related Differences in Selective Attention Are Captured by an Early Event-Related Potential

    OpenAIRE

    Baskin–Sommers, Arielle; Curtin, John J.; Li, Wen; Newman, Joseph P.

    2011-01-01

    According to the response modulation model, the poorly regulated behavior of psychopathic individuals reflects a problem reallocating attention to process peripheral information while engaged in goal-directed behavior (Patterson & Newman, 1993). We evaluated this tenet using male prisoners and an early event-related potential component (P140) to index attentional processing. In all task conditions, participants viewed and categorized letter stimuli that could also be used to predict electric ...

  16. The method of assessment of solar potential for selected area with use Geographical Information Systems

    Directory of Open Access Journals (Sweden)

    Netzel P.

    2012-10-01

    Full Text Available This paper describes a method for analyse the spatial distribution of solar energy potential based on calculated solar irradiation with use of GIS (Geographical Information System. Program GIS GRASS gives opportunity to create spatial distribution of solar radiation which is taking into account such important elements like: terrain, atmosphere, pollutants, water and aerosol in atmosphere, clouds. The use of GIS GRASS module – named r.sun gives opportunity to generate spatial distribution of solar radiation on Lower Silesia (south – west part of Poland. In this work the analyse of solar potential to obtain hot water in the individual household were done. This analyse was based on the amount of total solar radiation monthly sums generated by r.sun module. Spatial distribution of solar potential was used to classify the Lower Silesia region in terms of work efficiency solar installations. It is very usefully because it gives people information about the date of the return of the funds invested in the purchase of the solar collectors.

  17. Sensitive and selective determination of molybdenum by flow injection chemiluminescence method combined with controlled potential electrolysis technique

    International Nuclear Information System (INIS)

    A sensitive and selective flow injection chemiluminescence (CL) method combined with controlled potential electrolysis technique was described for the determination of molybdenum. The method is based on the chemiluminescence reaction of luminol with unstable molybdenum(III) in alkaline solution. The molybdenum(III) was on-line reduced from molybdenum(VI) via controlled potential electrolysis technique using a homemade flow-through carbon electrolytic cell at the potential of -0.6 V (versus Ag/AgCl). The method allows the determination of molybdenum in the 5.0x10-10 to 5.0x10-7 g ml-1 range with a limit of detection (3?) of 5x10-11 g ml-1 molybdenum. The relative standard deviation is 2.6% for the 1.0x10-9 g ml-1 molybdenum solution in 11 repeated measurements. This method was successfully applied to the determination of molybdenum in water samples

  18. Quantitative genetics of sugarcane : III. Potential for sucrose selection in Saccharum spontaneum.

    Science.gov (United States)

    Brown, A H; Daniels, J; Latter, B D; Krishnamurthi, M

    1969-01-01

    1. A project has been initiated to explore the possibilities of selection for higher levels of sucrose storage in the wild species S. spontaneum, using a representative sample of parental clones under conditions of natural crossing. 2. The aim of the programme is the development of superior clones to represent the wild species in conventional breeding programmes, which involve repeated backcrossing to S. officinarum. 3. An analysis of the first generation following the intercrossing of 21 parental types without emasculation, has demonstrated extensive genetic variability within and between progeny groups for fibre, sucrose, reducing sugars and yield grade. 4. Fibre and sucrose percent fresh weight are characters of high repeatability (0.4-0.6), and show little evidence of non-additive genetic effects. Individual plant performance for these characters can therefore be taken as a satisfactory basis for selection in this material. 5. The average degree of self-fertilization occurring under conditions of natural crossing has been estimated to be 0.69±.13, based on analyses of the quantitative genetic data for fibre and sucrose percent fresh weight. 6. The within-family genetic variance observed is of the order of five times that expected if the parental clones were homozygous. Much of the genetic variability induced within-families is therefore due to self-fertilization of heterozygous parental material, though the exact proportion cannot be deduced from the present data. 7. The initial response to selection for increased sucrose percent fresh weight is predicted to be of the order of 50% of the population mean. Comparable responses in subsequent cycles of the programme appear to be possible, provided an adequate degree of outcrossing can be achieved by controlled pollination techniques. 8. The genetic correlations between sucrose and other characters of importance are favourable to the objectives of the breeder, or else of a low order. There is no general relationship between the somatic chromosome number of the parental clones and the mean sucrose level of their progeny. PMID:24435287

  19. Potential productivity and yield gap of selected crops in the rainfed regions of India, Thailand, and Vietnam

    Directory of Open Access Journals (Sweden)

    Piara Singh

    2006-08-01

    Full Text Available ICRISAT's intervention in the project improving management of natural resources for sustainable rainfed agriculture funded by the Asian Development Bank aims to increase the productivity and sustainability of the medium and high water-holding capacity soils in the intermediate rainfall ecoregion of India, Thailand, and Vietnam. This study examined the potential yield and yield gap of selected crops predominantly grown in the target regions where the project is operational. We used the CROPGRO-soybean model to determine the potential yield and yield gap of soybean crop for several locations in India. For northeastern Thailand and northern Vietnam we compared the experimental yields with the farmers' current yields in the region to estimate the yield gaps. It has been estimated that for several locations in India the soybean yield gap ranged from 19% to 65% of potential yield. For northeastern Thailand the yield gap for paddy rice, upland rice, maize, and soybean ranged from 11% to 67% of their respective potential yields. In northern Vietnam the farmers' maize yields were two-third of the potential yield; however, groundnut and soybean have a yield gap of 40 to 60% of potential yield. Various constraints limiting crop yields in these regions have been highlighted. It is suggested that location-specific integrated approaches would be needed to bridge the yield gap of the predominant crops grown in the target regions.

  20. Visual encoding and fixation target selection in free viewing: presaccadic brain potentials

    Directory of Open Access Journals (Sweden)

    Andrey R Nikolaev

    2013-06-01

    Full Text Available In scrutinizing a scene, the eyes alternate between fixations and saccades. During a fixation, two component processes can be distinguished: visual encoding and selection of the next fixation target. We aimed to distinguish the neural correlates of these processes in the electrical brain activity prior to a saccade onset. Participants viewed color photographs of natural scenes, in preparation for a change detection task. Then, for each participant and each scene we computed an image heat map, with temperature representing the duration and density of fixations. The temperature difference between the start and end points of saccades was taken as a measure of the expected task-relevance of the information concentrated in specific regions of a scene. Visual encoding was evaluated according to whether subsequent change was correctly detected. Saccades with larger temperature difference were more likely to be followed by correct detection than ones with smaller temperature differences. The amplitude of presaccadic activity over anterior brain areas was larger for correct detection than for detection failure. This difference was observed for short “scrutinizing” but not for long “explorative” saccades, suggesting that presaccadic activity reflects top-down saccade guidance. Thus, successful encoding requires local scanning of scene regions which are expected to be task-relevant. Next, we evaluated fixation target selection. Saccades “moving up” in temperature were preceded by presaccadic activity of higher amplitude than those “moving down”. This finding suggests that presaccadic activity reflects attention deployed to the following fixation location. Our findings illustrate how presaccadic activity can elucidate concurrent brain processes related to the immediate goal of planning the next saccade and the larger-scale goal of constructing a robust representation of the visual scene.

  1. Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling

    Directory of Open Access Journals (Sweden)

    Wikberg Jarl ES

    2005-03-01

    Full Text Available Abstract Background Proteochemometrics is a new methodology that allows prediction of protein function directly from real interaction measurement data without the need of 3D structure information. Several reported proteochemometric models of ligand-receptor interactions have already yielded significant insights into various forms of bio-molecular interactions. The proteochemometric models are multivariate regression models that predict binding affinity for a particular combination of features of the ligand and protein. Although proteochemometric models have already offered interesting results in various studies, no detailed statistical evaluation of their average predictive power has been performed. In particular, variable subset selection performed to date has always relied on using all available examples, a situation also encountered in microarray gene expression data analysis. Results A methodology for an unbiased evaluation of the predictive power of proteochemometric models was implemented and results from applying it to two of the largest proteochemometric data sets yet reported are presented. A double cross-validation loop procedure is used to estimate the expected performance of a given design method. The unbiased performance estimates (P2 obtained for the data sets that we consider confirm that properly designed single proteochemometric models have useful predictive power, but that a standard design based on cross validation may yield models with quite limited performance. The results also show that different commercial software packages employed for the design of proteochemometric models may yield very different and therefore misleading performance estimates. In addition, the differences in the models obtained in the double CV loop indicate that detailed chemical interpretation of a single proteochemometric model is uncertain when data sets are small. Conclusion The double CV loop employed offer unbiased performance estimates about a given proteochemometric modelling procedure, making it possible to identify cases where the proteochemometric design does not result in useful predictive models. Chemical interpretations of single proteochemometric models are uncertain and should instead be based on all the models selected in the double CV loop employed here.

  2. Relation between methanogenic archaea and methane production potential in selected natural wetland ecosystems across China

    Directory of Open Access Journals (Sweden)

    D. Y. Liu

    2011-02-01

    Full Text Available Methane (CH4 emissions from natural wetland ecosystems exhibit large spatial variability at regional, national, and global levels related to temperature, water table, plant type and methanogenic archaea etc. To understand the underlying factors that induce spatial differences in CH4 emissions, and the relationship between the population of methanogenic archaea and CH4 production potential in natural wetlands around China, we measured the CH4 production potential and the abundance of methanogenic archaea in vertical soil profiles sampled from the Poyang wetland in the subtropical zone, the Hongze wetland in the warm temperate zone, the Sanjiang marsh in the cold temperate zone, and the Ruoergai peatland in the Qinghai-Tibetan Plateau in the alpine climate zone. The top soil layer had the highest population of methanogens (1.07–8.29 × 109 cells g?1 soil in all wetlands except the Ruoergai peatland and exhibited the maximum CH4 production potential measured at the mean in situ summer temperature. There is a significant logarithmic correlation between the abundance of methanogenic archaea and the soil organic carbon (R2 = 0.72, P < 0.001, n = 13 and between the abundance of methanogenic archaea and the total nitrogen concentrations (R2 = 0.76, P < 0.001, n = 13 in wetland soils. This indicates that the amount of soil organic carbon may affect the population of methanogens in wetland ecosystems. While the CH4 production potential is not significantly related to methanogen population (R2 = 0.01, P > 0.05, n = 13, it is related to the dissolved organic carbon concentration (R2 = 0.31, P = 0.05, n = 13. This suggests that the methanogen population might be not an effective index for predicting the CH4 production in wetland ecosystems. The CH4 production rate of the top soil layer increases with increasing latitude, from 273.64 ?g CH4 kg?1 soil d?1 in the Poyang wetland to 664.59 ?g CH4 kg?1 soil d?1 in the Carex lasiocarpa marsh of the Sanjiang Plain. We conclude that CH4 production potential in the freshwater wetlands of Eastern China is mainly affected by the supply of methanogenic substrates rather than temperature; in contrast, low summer temperatures at high elevations in the Ruoergai peatland of the Qinghai–Tibetan Plateau result in the presence of dominant species of methanogens with low CH4 production potential, which in turn suppresses CH4 production.

  3. Effect of midazolam on the auditory event-related potential: measures of selective attention.

    Science.gov (United States)

    Reinsel, R A; Veselis, R A; Heino, R; Miodownik, S; Alagesan, R; Bedford, R F

    1991-11-01

    To elucidate the delayed effects of midazolam, we assessed electrophysiologic and motor responses by measuring auditory event-related potentials and a button-press reaction time response in 10 normal volunteers (aged 25-36 yr). Fifty minutes after intravenous infusion of 0.07 mg/kg of midazolam, subjects were mildly sedated, oriented, and readily responsive to verbal commands. To obtain ERPs, frequent tones (85%: 1000 Hz) and rare tones (15%: 2500 Hz) were presented at intervals of 1.5 s. Electroencephalographic signals were collected from FZ, CZ, and PZ for 1000 ms after stimulus presentation until 40 artifact-free rare-tone responses were obtained (average time, 6 min). Peak-to-peak amplitudes and latencies for N2, P3, and the subsequent negative slow wave (N3) were averaged within condition and were analyzed by repeated measures analysis of variance. After midazolam infusion, there was a 50% decrease in amplitude of P3 in response to target tones (P less than 0.006), whereas N3 latency increased by 40 ms (P less than 0.05). Event-related potential amplitudes were still significantly larger to rare (target) stimuli (P less than 0.003) after midazolam infusion. Although reaction time increased by 70 ms (P = 0.031), performance accuracy remained unchanged. Self-ratings of sleepiness and concentration show that a significant sedation effect was still present 50 min after infusion. Although routine clinical examination may be normal, full recovery from the effects of a typical intravenous dose of midazolam requires more than 50 min. The potential for adverse drug interaction, particularly with narcotics, is still present at this time. PMID:1952143

  4. Antimalarial Activity of Potential Inhibitors of Plasmodium falciparum Lactate Dehydrogenase Enzyme Selected by Docking Studies

    OpenAIRE

    Penna-Coutinho, Julia; Cortopassi, Wilian Augusto; Oliveira, Aline Alves; França, Tanos Celmar Costa; Krettli, Antoniana Ursine

    2011-01-01

    The Plasmodium falciparum lactate dehydrogenase enzyme (PfLDH) has been considered as a potential molecular target for antimalarials due to this parasite's dependence on glycolysis for energy production. Because the LDH enzymes found in P. vivax, P. malariae and P. ovale (pLDH) all exhibit ?90% identity to PfLDH, it would be desirable to have new anti-pLDH drugs, particularly ones that are effective against P. falciparum, the most virulent species of human malaria. Our present work used docki...

  5. Carbon storage and sequestration potential of selected tree species in India

    OpenAIRE

    Kaul, M.; Mohren, G. M. J.; Dadhwal, V.K.

    2010-01-01

    A dynamic growth model (CO2FIX) was used for estimating the carbon sequestration potential of sal (Shorea Robusta Gaertn. f.), Eucalyptus (Eucalyptus Tereticornis Sm.), poplar (Populus Deltoides Marsh), and teak (Tectona Grandis Linn. f.) forests in India. The results indicate that long-term total carbon storage ranges from 101 to 156 Mg C?ha?1, with the largest carbon stock in the living biomass of long rotation sal forests (82 Mg C?ha?1). The net annual carbon sequestration rates were achie...

  6. Petrography, geochemistry and regional significance of crystalline klippen in the Garhwal Lesser Himalaya, India

    Indian Academy of Sciences (India)

    R Islam; S K Ghosh; S Vyshnavi; Y P Sundriya

    2011-06-01

    Uphalda gneisses (UG) is a crystalline klippe located near Srinagar in Garhwal Himalaya. These gneisses are compared with Debguru porphyroids (DP) (? Ramgarh group) of Garhwal–Kumaun Himalaya and Baragaon mylonitic gneisses (BMG) of Himachal Himalaya. Petrographic study reveals that the deformation of UG was initiated at higher temperature (above 350°C) and continued till lowering of temperature and deformation led to the mylonitization. Geochemically, these granitic gneisses (UG, DP and BMG) exhibit similar composition. Features such as high molecular A/CNK value (< 1), presence of normative corundum and absence of normative diopside, enhanced Rb/Sr, Rb/Zr ratios, enrichment of Th and containing rounded zircons support their crustally-derived S-type granitic nature. The linear plot in major oxides is interpreted in terms of fractional crystallization processes. Mantle normalized multi-element spider diagram of UG illustrates depletion of Ba, Nb, Sr, P and Ti and enrichment of Th and show similarities with DP and BMG. Similarities were observed in lithology, petrographic characters and chemical composition of UG, DP, BMG and Ulleri augen gneisses (Nepal). Comparison with the rocks of Higher Himalayan crystallines (? Vaikrita), suggests that these rocks (UG) are not transported from Higher Himalaya as understood earlier. This study however proposes that, these gneissic bodies represent an older basement occurring as a tectonic sliver which emplaced within the cover sequence as wedges at different structural levels. This is a regional phenomena observed throughout the Lesser Himalayan region.

  7. Radon/helium studies for earthquake prediction N-W Himalaya

    International Nuclear Information System (INIS)

    The paper presents the preliminary data of radon monitoring stated in the Himalayan orogenic belt. Radon anomalies are correlated with microseismic activity in the N-W Himalaya. The He/Rn ratio will be used as a predictive tool for earthquakes

  8. Recruitment of hornbill-dispersed trees in hunted and logged forests of the Indian Eastern Himalaya.

    Science.gov (United States)

    Sethi, Pia; Howe, Henry F

    2009-06-01

    Hunting of hornbills by tribal communities is widespread in logged foothill forests of the Indian Eastern Himalaya. We investigated whether the decline of hornbills has affected the dispersal and recruitment of 3 large-seeded tree species. We hypothesized that 2 low-fecundity tree species, Chisocheton paniculatus and Dysoxylum binectariferum (Meliaceae) bearing arillate fruits, are more dispersal limited than a prolifically fruiting drupaceous tree Polyalthia simiarum (Annonaceae), which has potential dispersers other than hornbills. We estimated the abundance of large avian frugivores during the fruiting season along transects in 2 protected and 2 disturbed forests. We compared recruitment of the tree species near (<10 m) and far (10-40 m) from parent trees at protected and disturbed sites. Median abundance of Great (Buceros bicornis), Wreathed (Aceros undulatus), and Oriental Pied Hornbills (Anthracoceros albirostris) were significantly lower in disturbed forests, but sites did not differ in abundances of the Mountain Imperial Pigeon (Ducula badia). Overall, tree species showed more severely depressed recruitment of seedlings (77% fewer) and juveniles (69% fewer) in disturbed than in protected forests. In disturbed forests, 93% fewer seedlings of C. paniculatus were beyond parental crowns, and a high number of all seedlings (42%) accumulated directly under reproductive adults. In contrast, D. binectariferum and P. simiarum were recruitment rather than dispersal limited, with fewer dispersed seedlings surviving in disturbed than in protected forests. Results are consistent with the idea that disturbance disrupts mutualisms between hornbills and some large-seeded food plants, with the caveat that role redundancy within even small and specialized disperser assemblages renders other tree species less vulnerable to loss of regular dispersal agents. PMID:19220369

  9. Sporadic, rainfall triggered landslides and debris flows in the monsoon, Nepal Himalaya

    Science.gov (United States)

    Fort, Monique; Etienne, Cossart; Alexis, Conte; Natacha, Gribenski; Gilles, Arnaud-Fassetta

    2010-05-01

    Small river catchments play a major role in the overall denudation of the Himalayas, because they may generate extreme, geomorphic events. We characterize their potential impacts on the morphology and functioning of trunk rivers, and indirectly on infrastructure and settlements located along the valley floor. Our study case, the Ghatte Khola, is an intermittent tributary of the Kali Gandaki (Western Nepal) affected by occasional debris flow events. The cause of the debris flows is a persistent planar slide zone (dip slope) that is reactivated by pre- or monsoon heavy rainfall on the upper, forested catchment. As a result, the narrow valley of the upstream part of the tributary is temporary clogged by slide masses, until sudden, landslide outburst floods occur. Downstream, where the channel is entrenched across a 5-8 m thick debris fan, the functioning of successive debris flows cause bank erosion and stream channel widening. At the junction with the Kali Gandaki, the flows may aggrade debris volumes large enough to dam the Kali Gandaki for a few hours and cause the level of this major river to rise more than 5 m upstream. During the last 40 years, pulsed aggradations transferred erosion point to the opposite (left bank) side of the Kali Gandaki. This ephemeral, yet threatening behaviour of the stream, occurs every two or three years, according to field investigations (geomorphic mapping, sediment analysis) and interviews of villagers. We present various scenarios simulated using the SAGA-GIS cellular automata combined with a Digital Elevation Model. We discuss the available rainfall intensity-duration thresholds susceptible to trigger Himalayan landslides. Our study suggests that such high-magnitude/low-frequency events are very efficient to foster sediment fluxes and create temporary sediment storages in Himalayan valleys, a fact that is to be considered prior to any new settlement and road design in a country where infrastructures are rapidly developing.

  10. Volatile organic compounds over Eastern Himalaya, India: temporal variation and source characterization using Positive Matrix Factorization

    Directory of Open Access Journals (Sweden)

    C. Sarkar

    2014-12-01

    Full Text Available A first ever study on the characterization of volatile organic compounds (VOCs has been made over a Himalayan high altitude station in India. A total of 18 VOCs (mono aromatics-BTEX (benzene, toluene, ethylbenzene, xylene, non-BTEX substituted aromatics and halocarbon have been measured over Darjeeling (27.01° N, 88.15° E, 2200 m a.s.l. in the eastern Himalaya in India during the period of July 2011–June 2012. The annual average concentration of the sum of 18 target VOCs (TVOC was 376.3 ± 857.2 ?g m?3. Monoaromatics had the highest contribution (72% followed by other substituted aromatics (22% and halocarbon (6% compounds. Toluene was the most abundant VOC in the atmosphere of Darjeeling with the contribution of ~37% to TVOC followed by benzene (~21%, ethylbenzene (~9% and xylenes (~6%. TVOC concentrations were highest during the postmonsoon season with minimum solar radiation and lowest during the premonsoon season with maximum solar radiation. Anthropogenic activities related mainly to tourists like diesel and gasoline emissions, biomass and coal burning, use of solvent and solid waste emissions were almost equal in both the seasons. Seasonal variation in TVOCs over Darjeeling was mainly governed by the incoming solar radiation rather than the emission sources. Source apportionment study using Positive Matrix Factorization (PMF model indicated that major fraction of (~60% TVOC were contributed by diesel and gasoline exhausts followed by solvent evaporation (18% and other sources. Diesel exhaust was also found to have the maximum potential in tropospheric ozone formation. The atmospheric loading of BTEX over Darjeeling was found to be comparable with several Indian metro cities and much higher than other cities around the world.

  11. Patterns of paternity skew among polyandrous social insects : what can they tell us about the potential for sexual selection?

    DEFF Research Database (Denmark)

    Jaffé, Rodolfo; Garcia-Gonzalez, Francisco

    2012-01-01

    Monogamy results in high genetic relatedness among offspring and thus it is generally assumed to be favored by kin selection. Female multiple mating (polyandry) has nevertheless evolved several times in the social Hymenoptera (ants, bees, and wasps), and a substantial amount of work has been conducted to understand its costs and benefits. Relatedness and inclusive fitness benefits are, however, not only influenced by queen mating frequency but also by paternity skew, which is a quantitative measure of paternity biases among the offspring of polyandrous females. We performed a large-scale phylogenetic analysis of paternity skew across polyandrous social Hymenoptera. We found a general and significant negative association between paternity frequency and paternity skew. High paternity skew, which increases relatedness among colony members and thus maximizes inclusive fitness gains, characterized species with low paternity frequency. However, species with highly polyandrous queens had low paternity skew, with paternity equalized among potential sires. Equal paternity shares among fathers are expected to maximize fitness benefits derived from genetic diversity among offspring. We discuss the potential for postcopulatory sexual selection to influence patterns of paternity in social insects, and suggest that sexual selection may have played a key, yet overlooked role in social evolution.

  12. Topical capsaicin selectively attenuates heat pain and A delta fiber-mediated laser-evoked potentials.

    Science.gov (United States)

    Beydoun, A; Dyke, D B; Morrow, T J; Casey, K L

    1996-01-01

    Cutaneous stimulation with CO2 laser pulses activates A delta of nociceptive afferents and evokes late cerebral potentials (LEPs), the amplitude of which correlates parametrically with the perceived magnitude estimation of laser pulses. Capsaicin is known to desensitize the nociceptive terminals of C fibers. In this double-blind, vehicle-controlled experiment, we tested the hypothesis that topical capsaicin would inactivate A delta afferents and lead to an attenuation of the LEPs. Subjects applied capsaicin cream to the dorsum of one hand and vehicle cream to the other 3 times daily for a period of 5 weeks. At weekly intervals before starting, during administration and after discontinuation of capsaicin, LEPs were recorded and psychophysical thresholds and magnitude estimation for several sensory modalities were determined. The results of this study showed that topical capsaicin significantly and reversibly decreased the magnitude estimation of suprathreshold heat pain, laser pulses and amplitude of the LEPs. There was no statistically significant difference in light touch, deep pain and mechanical pain detection thresholds between the capsaicin- and vehicle-treated hands. It indicated that topical capsaicin caused a definite functional and reversible inactivation of A delta nociceptive afferent transmission. The decline in the magnitude estimation of laser pulses concomitantly with the attenuation of LEP amplitudes supports the hypothesis that some A delta afferents mediate noxious heat in humans. These findings demonstrate the usefulness of LEP in the physiological evaluation of nociceptive pathways and its potential usefulness in objectively documenting the effect of pharmacological treatment on pain perception. PMID:8826506

  13. Potentials of selected metal alloys in sea water at elevated temperatures

    International Nuclear Information System (INIS)

    Sixteen metal alloys were studied in aerated sea water at temperatures up to 2000C, and five of these were further studied in deaerated sea water in the same temperature range. Galvanic series are reported for temperatures of 30, 100, 160, and 2000C in an autoclave, and for a trough at ambient conditions. The general effect of increased temperature in both aerated and deaerated sea water was to increase the electronegativity of most metals, and to reduce the spread between the median potential values. At 2000C, the metals merged into two groupings: aluminum and zinc being the most active, other metals were appreciably less negative. In contrast to other metals, zinc and carbon steel showed a tendency toward nobility at higher temperatures. Very small differences were found between the galvanic potentials of most metals in deaerated sea water as compared with these metals in aerated sea water. Titanium appeared to be the exception, being more active in deaerated sea water above 1200C

  14. Phytoremediation potential of selected plants for nitrate and phosphorus from ground water.

    Science.gov (United States)

    Sundaralingam, T; Gnanavelrajah, N

    2014-01-01

    The phytoremediation potential of three aquatic plants namely, water lettuce (Pistia stratioes), water hyacinth (Eichhornia crassipes), and water spinach (Ipomoea aquatica) for nitrate N and phosphorus from nutrient treated ground water was assessed. A total of twelve treatment combinations including four levels of nitrate (expressed as nitrate N 0, 20, 40, and 60 mg/l) and three levels of phosphorus (0, 20, and 40 mg/l) were treated for the total volume of 1 and 20 liters of water respectively, for Pistia stratiotes and Eichhornia crassipes. For Ipomoea aquatica ten treatment combinations with five levels of nitrate N (0, 10, 20, 40, and 50 mg/l) and two levels of phosphorus (0 and 5 mg/l) were treated to 3 liters of water. The design used was a two factor factorial with three replicates. Water was analyzed at weekly interval for nitrate N and phosphorus. Pistia stratiotes, Eichhornia crassipes and Ipomoea aquatica had the potential to remove nitrate N between 61.5-91.8%, 40-63.5%, and 29.3-75% during the period of six, three and three and weeks, respectively. In addition, 90-99%, 75-97.2%, and 75-83.3% of phosphorus was removed from water by Pistia stratiotes, Eichhornia crassipes and Ipomoea aquatica respectively, during the same period. PMID:24912224

  15. Energy performance contracting - energy saving potential of selected energy conservation measures (ECM)

    Energy Technology Data Exchange (ETDEWEB)

    Johansson, M. (Dansk Energi Analyse A/S, Frederiksberg (Denmark)); Langkilde, G.; Olesen, Bjarne W. (Technical Univ. of Denmark, ICIEE, Kgs. Lyngby (Denmark)); Moerck, O. (Cenergia Energy Consultants, Herlev (Denmark)); Sundman, O. (DONG Energy, Copenhagen (Denmark)); Engelund Thomsen, K. (Aalborg Univ., SBi, Hoersholm (Denmark))

    2008-09-15

    This report has been developed under the research project 'Etablering af grundlag for energitjenester i Danmark' (project number: ENS-33031-0185) under the Danish research programme - EFP. The objective of this project has been to contribute to the utilisation of the large potential for energy conservations in the building sector within the public, industry and service sectors through the development of a better basis for decision making for both the Energy Service Companies (ESCOes) and the building owners. The EU directive on Energy Service Contracting points at the buildings as the area where the biggest potential market for energy services and energy efficiency improvements are. The EFP-project has two parts: (1) A Danish part and (2) participation in the international cooperation project 'Holistic Assesment Tool-Kit on Energy Efficient Retrofit Measures for Government Buildings (EnERGo)', Annex 46 under the IEA R and D program 'Energy Conservation In Buildings And Community Systems' (ECBCS). This report describes the Danish contributions to the IEA projects subtask B, which has a primary objective to develop a database of energy conservation measures (ECM) with descriptions and performance characteristics of these. (au)

  16. Potential and limitations of multidecadal satellite soil moisture observations for selected climate model evaluation studies

    Directory of Open Access Journals (Sweden)

    A. Loew

    2013-09-01

    Full Text Available Soil moisture is an essential climate variable (ECV of major importance for land–atmosphere interactions and global hydrology. An appropriate representation of soil moisture dynamics in global climate models is therefore important. Recently, a first multidecadal, observation-based soil moisture dataset has become available that provides information on soil moisture dynamics from satellite observations (ECVSM, essential climate variable soil moisture. The present study investigates the potential and limitations of this new dataset for several applications in climate model evaluation. We compare soil moisture data from satellite observations, reanalysis and simulations from a state-of-the-art land surface model and analyze relationships between soil moisture and precipitation anomalies in the different dataset. Other potential applications like model parameter optimization or model initialization are not investigated in the present study. In a detailed regional study, we show that ECVSM is capable to capture well the interannual and intraannual soil moisture and precipitation dynamics in the Sahelian region. Current deficits of the new dataset are critically discussed and summarized at the end of the paper to provide guidance for an appropriate usage of the ECVSM dataset for climate studies.

  17. SOIL CARBON DYNAMICS AND GLOBAL WARMING POTENTIAL OF SELECTED SOIL SERIES AND LANDUSE CATEGORIES

    Directory of Open Access Journals (Sweden)

    Feba Merin Chacko

    2014-03-01

    Full Text Available Land use conversion is usually accompanied by a decline in soil organic carbon. This work is aimed to determine the soil organic carbon affected by the multiple land use in a particular soil series. The study was conducted in Ustic Haplohumults soil series of Kottayam district of Kerala including land uses like Cropland, Wetland, Agricultural land, Homestead and Mixed vegetation land. Change in land use induced significant losses of soil and particulate organic carbon. The maximum SOC content (7.39% was observed in abandoned paddy field which is nearly 89% more than the lowest values of 0.76% recorded from the Homestead soil. Soil carbon sequestration potential of different land uses varies on spatial and temporal basis along with the interplay of environmental externalities. Potential for CO2 production and global warming of various soils was in accordance with C mineralization and this explains the role and capacity of various land use under consideration to store and release carbon. In the present study it was found that the soils of coconut plantation serve as a better system in terms of maximum SOC storage and minimum carbon emission. The present study reveals the significance and importance of specific land use category which is optimal for particular soil series towards soil carbon storage.

  18. Do Himalayan glaciers defy global warming? Case studies from NW Himalaya, India

    Science.gov (United States)

    Ganjoo, R. K.

    2009-12-01

    The Himalaya is influenced by two major climatic systems that are mid-latitude Westerlies and South Asia Indian Monsoon. The east and south slopes of Himalaya are greatly influenced by the monsoon, whereas the north and west ranges, e.g. Karakorum, have a supply of moisture by mid-latitude Westerlies. The greatest concentration of glaciers occurs in Karakorum Mountains and the western Himalaya which have the longest glaciers outside the polar regions. There is important contrast in the seasonal relationship between precipitation and ablation along the Himalaya. Ladakh and Zanskar hold special geographical significance for the study of climate change, if any. Both the areas lie far away from the effect of South West Indian Monsoon (SWIM) that has largely been identified as the moisture carrier for rest of Himalaya. The moisture laden SWIM bring down the precipitation in the form of snow in most of Himalaya that nourishes the glaciers. On the contrary, the Himalaya in Leh and Zanskar region receive a major contribution of snow through Westerlies during the winter season. Hence, the depletion or growth of glaciers of Leh and Zanskar is related to the weakening or strengthening of Westerlies. The field and satellite imageries study of secular movement of terminus of Durung Drung glacier, Kangriz glacier and Siachen glacier does not reveal any significant retreat. The degeneration of snout could be due to several reasons, such as basin geomorphology, location of glacier on active fault, asynchronous behavior of feeders of the glacier, etc. However, the climate analysis of the area does not point any major change that has affected the health of the glacier in last decade or so.Precipitation in Upper Indus Basin (UIB)is concentrated in winter and spring months that provides principal source for accumulation of UIB glaciers. The climatic data for past four decades of UIB suggest that mean and minimum summer temperatures show cooling and large increase in diurnal temperature range.Reduction in the summer temperatures and positive trend in winter precipitation has resulted in reduced ablation and increased accumulation of Karakorum glaciers. The processes has translated in the expansion and thickening of glaciers that is much contrary to the accepted model of global warming and high glacier melting.

  19. Selection and Characterization of Single Chain Antibody Fragments Specific for Hsp90 as a Potential Cancer Targeting Molecule

    Directory of Open Access Journals (Sweden)

    Edyta Petters

    2015-08-01

    Full Text Available Heat shock proteins play an essential role in facilitating malignant transformation and they have been recognized as important factors in human cancers. One of the key elements of the molecular chaperones machinery is Hsp90 and it has recently become a target for anticancer therapeutic approaches. The potential and importance of Hsp90-directed agents becomes apparent when one realizes that disruption of Hsp90 function may influence over 200 oncogenic client proteins. Here, we described the selection and characterization of Hsp90-specific antibody fragments from commercially available Tomlinson I and J phage display libraries. The affinities of Hsp90-binding scFv variants were measured using SPR method. Then, based on the best clone selected, we performed the affinity maturation procedure and obtained valuable Hsp90-specific clones. The selected binders were expressed and applied for immunostaining, ELISA and SPR analysis using model cancer cell lines. All performed experiments confirmed the ability of selected antibodies to interact with the Hsp90. Therefore, the presented Hsp90-specific scFv, might be a starting point for the development of a novel antibody-based strategy targeting cancer.

  20. A simple electrochemical method for the rapid estimation of antioxidant potentials of some selected medicinal plants.

    Science.gov (United States)

    Amidi, Salimeh; Mojab, Faraz; Bayandori Moghaddam, Abdolmajid; Tabib, Kimia; Kobarfard, Farzad

    2012-01-01

    Clinical and Epidemiological studies have shown that a diet rich in fruits and vegetables is associated with a decreased risk of cardiovascular diseases, cancers and other related disorders. These beneficial health effects have been attributed in part to the presence of antioxidants in dietary plants. Therefore screening for antioxidant properties of plant extracts has been one of the interests of scientists in this field. Different screening methods have been reported for the evaluation of antioxidant properties of plant extracts in the literature. In the present research a rapid screening method has been introduced based on cyclic voltammetry for antioxidant screening of some selected medicinal plant extracts. CYCLIC VOLTAMMETRY OF METHANOLIC EXTRACTS OF SEVEN MEDICINAL PLANTS: Buxus hyrcana, Rumex crispus, Achillea millefolium, Zataria multiflora, Ginkgo biloba, Lippia citriodora and Heptaptera anisoptera was carried out at different scan rates. Based on the interpretation of voltammograms, Rumex crispus, Achillea millefolium and Ginkgo biloba showed higher antioxidant capability than the others while Lippia citriodora contained the highest amount of antioxidants. Cyclic voltammetry is expected to be a simple method for screening antioxidants and estimating the antioxidant activity of foods and medicinal plants. PMID:25317192

  1. Virulence potential of Enterococcus gallinarum strains isolated from selected Nigerian traditional fermented foods

    Directory of Open Access Journals (Sweden)

    IYABO C. OLADIPO

    2014-08-01

    Full Text Available Five Enterococcus isolates from some Nigerian traditional fermented foods were identified as Enterococcus gallinarum by using phenotypic and genotypic tests. Safety properties such as antibiotic susceptibility, virulence gene detection, haemolysin, gelatinase and bacteriocin production were determined using standard methods. There was no resistance to clinically relevant antibiotics. Virulence gene for collagen binding antigen and aggregation substance were detected in 60% of the E. gallinarum strains; while surface adhesin was detected in 20%, but none of the strains had cytolysin activator and gelatinase. Phenotype characterizations of the E. gallinarum isolates indicated that none of the isolates produced haemolysin and gelatinase. Enterococcus gallinarum C103 and U82 had no antimicrobial activity against all the selected bacteria pathogens while E. gallinarum W184, T71 and W21 were active against some of the indicator bacteria pathogens. Only E. gallinarum T71 and W21 showed broad spectra of antimicrobial activity. Combination of virulence factors did not appear in these food isolates. Therefore, these strains particularly the two strains with high spectra of antimicrobial activity could be exploited as functional starters in foods.

  2. Potential of Selective Estrogen Receptor Modulators as Treatments and Preventives of Breast Cancer

    Science.gov (United States)

    Peng, Jing; Sengupta, Surojeet; Jordan, V Craig

    2013-01-01

    Estrogen plays vital roles in human health and diseases. Estrogen mediates its actions almost entirely by binding to estrogen receptors (ER), alpha and beta which further function as transcription factors. Selective estrogen receptor modulators (SERMs) are synthetic molecules which bind to ER and can modulate its transcriptional capabilities in different ways in diverse estrogen target tissues. Tamoxifen, the prototypical SERM, is extensively used for targeted therapy of ER positive breast cancers and is also approved as the first chemo-preventive agent for lowering breast cancer incidence in high risk women. The therapeutic and preventive efficacy of tamoxifen was initially proven by series of experiments in the laboratory which laid the foundation of its clinical use. Unfortunately, use of tamoxifen is associated with de-novo and acquired resistance and some undesirable side effects. The molecular study of the resistance provides an opportunity to precisely understand the mechanism of SERM action which may further help in designing new and improved SERMs. Recent clinical studies reveal that another SERM, raloxifene, which is primarily used to treat post-menopausal osteoporosis, is as efficient as tamoxifen in preventing breast cancers with fewer side effects. Overall, these findings open a new horizon for SERMs as a class of drug which not only can be used for therapeutic and preventive purposes of breast cancers but also for various other diseases and disorders. Major efforts are therefore directed to make new SERMs with a better therapeutic profile and fewer side effects. PMID:19519291

  3. Latency change estimation for evoked potentials via frequency selective adaptive phase spectrum analyzer.

    Science.gov (United States)

    Kong, X; Qiu, T

    1999-08-01

    This paper addresses the problem of detecting and estimating latency changes in evoked potentials (EP's). EP's have been widely used to quantify neurological system properties. Transient and time-varying changes in latency may indicate impending neurological injury. Traditional time averaging and correlation methods for EP latency estimation are inefficient under low signal-to-noise ratio (SNR) and/or strong periodic interference conditions. This paper proposes an adaptive phase spectral time delay estimation method to detect and estimate the time-varying latency changes when both the SNR and the signal-to-interference ratio (SIR) are low. A theoretical analysis and computer simulation demonstrate that the proposed method can track the time-varying latency changes effectively and accurately when both the SNR and the SIR are as low as -5 dB. The method is also suitable for real time detection and estimation of the latency changes. PMID:10431466

  4. Investigation of therapeutic potentials of some selected medicinal plants using neutron activation analysis

    International Nuclear Information System (INIS)

    Series of attempts were made to investigate concentrations of trace elements and their therapeutic properties in various medicinal plants. In this study, samples of some commonly used plants were collected from Bauchi State, Nigeria. They includes leaves of azadirachta indica (neem), Moringa Oleifera (moringa), jatropha curcas (purgin Nut), guiera senegalensis (custard apple) and anogeissus leiocarpus (African birch). These samples were analyzed for their trace elements contents with both short and long irradiation protocols of Instrumental Neutron Activation Analysis (INAA) at Nigerian Research Reactor-1 (NIRR-1) of Ahmadu Bello University, Zaria, Nigeria. The level of trace elements found varies from one sample to another, with some reported at hundreds of mg/Kg dry weight. The results have been compared with the available literature data. The presence of these trace elements indicates promising potentials of these plants for relief of certain ailments

  5. Investigation of therapeutic potentials of some selected medicinal plants using neutron activation analysis

    Science.gov (United States)

    Abubakar, Sani; Usman, Ahmed Rufa'i.; Isa, Nasiru Fage; Khandaker, Mayeen Uddin; Abubakar, Nuraddeen

    2015-04-01

    Series of attempts were made to investigate concentrations of trace elements and their therapeutic properties in various medicinal plants. In this study, samples of some commonly used plants were collected from Bauchi State, Nigeria. They includes leaves of azadirachta indica (neem), Moringa Oleifera (moringa), jatropha curcas (purgin Nut), guiera senegalensis (custard apple) and anogeissus leiocarpus (African birch). These samples were analyzed for their trace elements contents with both short and long irradiation protocols of Instrumental Neutron Activation Analysis (INAA) at Nigerian Research Reactor-1 (NIRR-1) of Ahmadu Bello University, Zaria, Nigeria. The level of trace elements found varies from one sample to another, with some reported at hundreds of mg/Kg dry weight. The results have been compared with the available literature data. The presence of these trace elements indicates promising potentials of these plants for relief of certain ailments.

  6. Investigation of therapeutic potentials of some selected medicinal plants using neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Abubakar, Sani; Isa, Nasiru Fage [Bayero University, Kano Nigeria (Nigeria); Usman, Ahmed Rufa’i [University of Malaya, Kuala Lumpur (Malaysia); Umaru Musa Yar’adua University, Katsina Nigeria (Nigeria); Khandaker, Mayeen Uddin [University of Malaya, Kuala Lumpur (Malaysia); Abubakar, Nuraddeen [Center for Energy Research and Training, Ahmadu Bello University, Zaria Nigeria (Nigeria)

    2015-04-24

    Series of attempts were made to investigate concentrations of trace elements and their therapeutic properties in various medicinal plants. In this study, samples of some commonly used plants were collected from Bauchi State, Nigeria. They includes leaves of azadirachta indica (neem), Moringa Oleifera (moringa), jatropha curcas (purgin Nut), guiera senegalensis (custard apple) and anogeissus leiocarpus (African birch). These samples were analyzed for their trace elements contents with both short and long irradiation protocols of Instrumental Neutron Activation Analysis (INAA) at Nigerian Research Reactor-1 (NIRR-1) of Ahmadu Bello University, Zaria, Nigeria. The level of trace elements found varies from one sample to another, with some reported at hundreds of mg/Kg dry weight. The results have been compared with the available literature data. The presence of these trace elements indicates promising potentials of these plants for relief of certain ailments.

  7. Selection and evaluation of potential burnable absorbers incorporated into modified TRISO particles

    Energy Technology Data Exchange (ETDEWEB)

    Washington, J., E-mail: jwashing@mines.edu; King, J., E-mail: kingjc@mines.edu; Shayer, Z., E-mail: zshayer@mines.edu

    2014-10-15

    Graphical abstract: - Highlights: • We evaluate possible burnable absorbers for modified TRISO fuels. • We model modified TRISO particle performance in MCNPX. • Modified particles decrease reactivity swing and increase reactor lifetime. • Modified particles generally result in negative thermal feedback. - Abstract: The quadruple isotropic (QUADRISO) particle concept modifies tri-structural-isotropic (TRISO) particles to add a layer of burnable absorber next to the fuel kernel. Previous studies have evaluated QUADRISO fuel particle designs for the transmutation of neptunium and plutonium, as a modification to the plutonium–thorium fuel cycle, and for excess reactivity management. This study screens the available nuclear isotope database to identify potential burnable absorbers for incorporation into modified TRISO fuel particles in a representative Very High-Temperature Reactor (VHTR). Based on this screening, eleven potential burnable absorbers are tested as QUADRISO burnable absorber layers, in either oxide or carbide forms. The addition of a burnable absorber layer to the TRISO fuel resulted in an increase in reactor operational lifetime in all cases considered in the present work when compared to a reactor with the same excess reactivity without burnable absorbers. The B{sub 4}C, CdO and Gd{sub 2}O{sub 3} cases resulted in the greatest operational lifetime, for the same initial excess reactivity, and the addition of these burnable absorbers to TRISO fuel particles decreased the magnitude of the excess reactivity change over the reactor lifetime when compared to the unmodified TRISO case. Thermal cross-section effects in QUADRISO particles generally result in excess reactivity decreasing with increasing temperature.

  8. Selection and evaluation of potential burnable absorbers incorporated into modified TRISO particles

    International Nuclear Information System (INIS)

    Graphical abstract: - Highlights: • We evaluate possible burnable absorbers for modified TRISO fuels. • We model modified TRISO particle performance in MCNPX. • Modified particles decrease reactivity swing and increase reactor lifetime. • Modified particles generally result in negative thermal feedback. - Abstract: The quadruple isotropic (QUADRISO) particle concept modifies tri-structural-isotropic (TRISO) particles to add a layer of burnable absorber next to the fuel kernel. Previous studies have evaluated QUADRISO fuel particle designs for the transmutation of neptunium and plutonium, as a modification to the plutonium–thorium fuel cycle, and for excess reactivity management. This study screens the available nuclear isotope database to identify potential burnable absorbers for incorporation into modified TRISO fuel particles in a representative Very High-Temperature Reactor (VHTR). Based on this screening, eleven potential burnable absorbers are tested as QUADRISO burnable absorber layers, in either oxide or carbide forms. The addition of a burnable absorber layer to the TRISO fuel resulted in an increase in reactor operational lifetime in all cases considered in the present work when compared to a reactor with the same excess reactivity without burnable absorbers. The B4C, CdO and Gd2O3 cases resulted in the greatest operational lifetime, for the same initial excess reactivity, and the addition of these burnable absorbers to TRISO fuel particles decreased the magnitude of the excess reactivity change over the reactor lifetime when compared to the unmodified TRISO case. Thermal cross-section effects in QUADRISO particles generally result in excess reactivity decreasing with increasing temperature

  9. The potential of nano-and microparticles for the selective complexation and separation of metal ions/radionuclides

    International Nuclear Information System (INIS)

    Nano- and microparticles for the selective complexation of metal ions and especially radionuclides on their surface are presented. Beside several applications of such magnetic and non-magnetic particles in the fields of bio-medicine, diagnostics, molecular biology, bio-inorganic chemistry and catalysis a high potential exists for the complexation of radionuclides from nuclear wastewater on particle surfaces. The magnetic properties of nano- and microparticles allow the fast magnetic separation of radionuclides from the radioactive liquid waste stream, for example. The removal of radionuclides from strongly acidic wastes requires a high stability of the particles in combination with the protection of the incorporated iron oxide. The covalent binding of selective chelators allows the fractionation of different types of radionuclides regarding the special needs of nuclear waste treatment. (author)

  10. Mountain range specific analog weather forecast model for northwest Himalaya in India

    Indian Academy of Sciences (India)

    D Singh; A Ganju

    2008-10-01

    Mountain range speci?c analog weather forecast model is developed utilizing surface weather observations of reference stations in each mountain range in northwest Himalaya (NW-Himalaya).The model searches past similar cases from historical dataset of reference observatory in each mountain range based on current situation.The searched past similar cases of each mountain range are used to draw weather forecast for that mountain range in operational weather forecasting mode, three days in advance.The developed analog weather forecast model is tested with the independent dataset of more than 717 days (542 days for Pir Panjal range in HP)of the past 4 winters (2003 –2004 to 2006 –2007).Independent test results are reasonably good and suggest that there is some possibility of forecasting weather in operational weather forecasting mode employing analog method over different mountain ranges in NW-Himalaya.Signi?cant difference in overall accuracy of the model is found for prediction of snow day and no-snow day over different mountain ranges, when weather is predicted under snow day and no-snow day weather forecast categories respectively.In the same mountain range,signi ?cant difference is also found in overall accuracy of the model for prediction of snow day and no-snow day for different areas.This can be attributed to their geographical position and topographical differences.The analog weather forecast model performs better than persistence and climatological forecast for day-1 predictions for all the mountain ranges except Karakoram range in NW-Himalaya.The developed analog weather forecast model may help as a guidance tool for forecasting weather in operational weather forecasting mode in different mountain ranges in NW-Himalaya.

  11. Phylogeography of microbial phototrophs in the dry valleys of the high Himalayas and Antarctica.

    Science.gov (United States)

    Schmidt, S K; Lynch, R C; King, A J; Karki, D; Robeson, M S; Nagy, L; Williams, M W; Mitter, M S; Freeman, K R

    2011-03-01

    High-elevation valleys in dry areas of the Himalayas are among the most extreme, yet least explored environments on Earth. These barren, rocky valleys are subjected to year-round temperature fluctuations across the freezing point and very low availability of water and nutrients, causing previous workers to hypothesize that no photoautotrophic life (primary producers) exists in these locations. However, there has been no work using modern biogeochemical or culture-independent molecular methods to test the hypothesis that photoautotrophs are absent from high Himalayan soil systems. Here, we show that although microbial biomass levels are as low as those of the Dry Valleys of Antarctica, there are abundant microbial photoautotrophs, displaying unexpected phylogenetic diversity, in barren soils from just below the permanent ice line of the central Himalayas. Furthermore, we discovered that one of the dominant algal clades from the high Himalayas also contains the dominant algae in culture-independent surveys of both soil and ice samples from the Dry Valleys of Antarctica, revealing an unexpected link between these environmentally similar but geographically very distant systems. Phylogenetic and biogeographic analyses demonstrated that although this algal clade is globally distributed to other high-altitude and high-latitude soils, it shows significant genetic isolation by geographical distance patterns, indicating local adaptation and perhaps speciation in each region. Our results are the first to demonstrate the remarkable similarities of microbial life of arid soils of Antarctica and the high Himalayas. Our findings are a starting point for future comparative studies of the dry valleys of the Himalayas and Antarctica that will yield new insights into the cold and dry limits to life on Earth. PMID:20826485

  12. Evaluation of antifungal potential of selected medicinal plants against human pathogenic fungi

    Directory of Open Access Journals (Sweden)

    Hayat Sakander

    2015-01-01

    Full Text Available Context: Evaluation of medicinal plants used in traditional medicine lead to novel bioactive compounds with antifungal activity that could be exploited as therapeutic agents. Aims: The aim was to screen selected medicinal plants for antifungal activity against three important human pathogenic fungi and to identify the broad group of phytochemicals responsible for the activity. Materials and Methods: A total of 8 medicinal plants were screened for antifungal activity against three human pathogenic fungi. Aqueous and the solvent extracts of the plant materials were prepared by polarity based solvent extraction. Antifungal activity was tested by well and disc diffusion methods. Minimum inhibitory concentration (MIC of the active extract was determined by micro-broth dilution technique. Phytochemical analysis of the active extract was done. Statistical Analysis Used: The results were statistically analysed by One-Way analysis of variance with Post-hoc Tukey?s B test at P < 0.05 using the? Software SPSS version 20 (IBM Corp. Armonk, NY Released 2011. Results: Significant antifungal activity was observed in the aqueous extracts of the fruits of Terminalia chebula (47.75 mm against Microsporum gypseum and the mesocarp of Persea americana (40.5 mm against Microsporum canis. Candida albicans was inhibited by the ethyl acetate (20 mm and aqueous extracts (16 mm of T. chebula fruits and aqueous extract of the seeds of Syzygium jambos (16 mm. The aqueous extract of mesocarp of P. americana showed lowest MIC value (312.5 ?g/ml against M. canis and M. gypseum. Phytochemical analysis of the active extracts revealed the presence of phenols, tannins, alkaloids and flavonoids. Conclusions: The study validates the use of the plants in the treatment of fungal infections and has provided important leads for the discovery of new plant-based antifungal agents.

  13. Utilization of the Potentials of Selected Microorganisms as Biocontrol and Biofertilizer for Enhanced Crop Improvement

    Directory of Open Access Journals (Sweden)

    E.O. Oyekanmi

    2008-01-01

    Full Text Available Some selected microorganisms isolated from rhizosphere of crops, were screened for their abilities to enhance crop growth and suppress plant parasitic nematodes; in screenhouse experiments. Two promising hybrids of soybean genotypes: TGx 1448-2E (medium duration and TGx 1485-1D (early maturing and a high yielding hybrid of maize genotype Oba Super 1 were used. Microorganisms assessed included the fungi: Trichoderma pseudokoningii, Trichoderma viride, Paecilomyces lilacinus, Aspergillus niger, Glomus mosseae and the rhizobacteria Pseudomonas fluorescens and Pseudomonas putida. One thousand juveniles of Meloidogyne incognita were applied to soybean, while five thousand Pratylenchus zeae (juveniles and adults were applied to maize. Fungal spores and rhizobacteria cells approximately 2.5x106 mL-1 concentration were applied per plant, for maize experiment. For soybean experiment, Bradyrhizobium japonicum (106 cells, Trichoderma pseudokoningii (6.8x106 spores and G. mosseae (200 spores were inoculated per plant. The effect of microorganism`s application was compared with a nematicide (carbofuran treatment, untreated control and a nematode only control. The parameters measured were nematode density, root damage due to plant parasitic nematode infection, relative leaf chlorophyll content and plant growth parameters. The inoculated beneficial microorganisms in most cases significantly (p?0.05 reduced the nematode density across the treatments in test crops by up to 79.6% and improved plant growth by up to 46.0%, when treatments performances were compared across treatments. Most of the beneficial microorganisms assessed have prospects of enhancing nematode management through nematode density reduction and improving crop production.

  14. Maternal use of selective serotonin reuptake inhibitors and risk of miscarriage - assessing potential biases

    DEFF Research Database (Denmark)

    Johansen, Rie Laurine Rosenthal; Mortensen, Laust Hvas

    2015-01-01

    BACKGROUND: The use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy has been associated with miscarriage, but the association may be biased by maternal mental illness, lifestyle and exposure misclassification. METHODS: A register study on all pregnancies in Denmark between 1996 and 2009 was conducted using individualised data from the Danish National Patient Register, the Medical Birth Register, the Danish Psychiatric Central Register, the Danish National Prescription database and the Danish National Birth Cohort (DNBC). RESULTS: A total of 1?191164 pregnancies were included in the study, of which 98275 also participated in the DNBC. Pregnancies exposed to SSRIs during or before pregnancy were more likely than unexposed pregnancies to result in first trimester miscarriage, hazard rate (HR)=1.08 [95% confidence interval (CI) 1.04, 1.13] and HR=1.26 [95% CI 1.16, 1.37], respectively. No difference was observed for second trimester miscarriage. SSRI-exposed pregnancies without a maternal depression/anxiety diagnosis from a psychiatric department were less likely to result in first trimester miscarriage than unexposed pregnancies with a diagnosis, HR=0.85 [95% CI 0.76, 0.95]. SSRI-exposed pregnancies were characterised by an unhealthier maternal lifestyle and mental health profile than unexposed pregnancies, whereas no convincing differences were observed between pregnancies exposed to SSRIs during versus before pregnancy. Substantial disagreement was found between prescriptions and self-reported use of SSRIs, but it did not affect the estimated hazard ratios. CONCLUSION: Confounding by indication and lifestyle in pregnancy may explain the association between SSRI use and miscarriage.

  15. Simple, Single Step Potential Measurement for the Determination of the Ultimate Detection Limit of Ion Selective Electrodes.

    Czech Academy of Sciences Publication Activity Database

    Bereczki, R.; Takács, B.; Gyurcsányi, R. E.; Tóth, K.; Nagy, G.; Langmaier, Jan; Lindner, E.

    2006-01-01

    Ro?. 18, 13-14 (2006), s. 1245-1253. ISSN 1040-0397 Grant ostatní: National Science Foundation Grants(XE) 0202207; National Science Foundation Grants(XE) 0335228; Hungarian Scientific Foundation(HU) F037977; Hungarian Scientific Foundation(HU) M041969; Hungarian Scientific Foundation(HU) T46403; Hungarian Scientific Foundation(HU) OM/PAL-112/2003; Hungarian Scientific Foundation(HU) OTKA-NSF 46146 Institutional research plan: CEZ:AV0Z40400503 Keywords : carrier based ion-selective electrodes * potential difference measurement * response range * detection limit Subject RIV: CG - Electrochemistry Impact factor: 2.444, year: 2006

  16. A fuzzy AHP based approach for selecting potential recovery facilities in a closed-loop supply chain

    Science.gov (United States)

    Nukala, Satish; Gupta, Surendra M.

    2005-11-01

    In this paper, we employ fuzzy AHP methodology for selecting potential recovery facilities in a closed-loop supply chain. This methodology utilizes triangular fuzzy numbers for pair-wise comparisons and the extent analysis method for the synthetic extent value of the fuzzy pair-wise comparisons and principle of comparison of fuzzy numbers to derive the weight vectors to address the criticism traditional AHP often faces due to its unbalanced scale of judgments and inability to handle inherent uncertainty in carrying out pair-wise comparisons. A numerical example is considered to illustrate the methodology.

  17. Energy regulation in China: Objective selection, potential assessment and responsibility sharing by partial frontier analysis

    International Nuclear Information System (INIS)

    To cope with the excessive growth of energy consumption, the Chinese government has been trying to strengthen the energy regulation system by introducing new initiatives that aim at controlling the total amount of energy consumption. A partial frontier analysis is performed in this paper to make a comparative assessment of the combinations of possible energy conservation objectives, new constraints and regulation strategies. According to the characteristics of the coordination of existing regulation structure and the optimality of regulation strategy, four scenarios are constructed and regional responsibilities are reasonably divided by fully considering the production technology in the economy. The relative importance of output objectives and the total amount controlling is compared and the impacts on the regional economy caused by the changes of regulation strategy are also evaluated for updating regulation policy. - Highlights: • New initiatives to control the total amount of energy consumption are evaluated. • Twenty-four regulation strategies and four scenarios are designed and compared. • Crucial regions for each sector and regional potential are identified. • The national goals of energy abatement are decomposed into regional responsibilities. • The changes of regulation strategy are evaluated for updating regulation policy

  18. Photogrammetry and Its Potential Application in Medical Science on the Basis of Selected Literature.

    Science.gov (United States)

    Ey-Chmielewska, Halina; Chru?ciel-Nogalska, Ma?gorzata; Fr?czak, Bogumi?a

    2015-01-01

    Photogrammetry is a science and technology which allows quantitative traits to be determined, i.e. the reproduction of object shapes, sizes and positions on the basis of their photographs. Images can be recorded in a wide range of wavelengths of electromagnetic radiation. The most common is the visible range, but near- and medium-infrared, thermal infrared, microwaves and X-rays are also used. The importance of photogrammetry has increased with the development of computer software. Digital image processing and real-time measurement have allowed the automation of many complex manufacturing processes. Photogrammetry has been widely used in many areas, especially in geodesy and cartography. In medicine, this method is used for measuring the widely understood human body for the planning and monitoring of therapeutic treatment and its results. Digital images obtained from optical-electronic sensors combined with computer technology have the potential of objective measurement thanks to the remote nature of the data acquisition, with no contact with the measured object and with high accuracy. Photogrammetry also allows the adoption of common standards for archiving and processing patient data. PMID:26469121

  19. Phytotoxicity of biosolids and screening of selected plant species with potential for mercury phytoextraction.

    Science.gov (United States)

    Lomonte, Cristina; Doronila, Augustine I; Gregory, David; Baker, Alan J M; Kolev, Spas D

    2010-01-15

    Mercury contaminated stockpiles of biosolids (3.5-8.4 mg kg(-1) Hg) from Melbourne Water's Western Treatment Plant (MW-WTP) were investigated to evaluate the possibility for their phytoremediation. Nine plant species (Atriplex codonocarpa, Atriplex semibaccata, Austrodanthonia caespitosa, Brassica juncea, Brassica napus, Gypsophila paniculata, Sorghum bicolor, Themeda triandra and Trifolium subterraneum) were screened for phytoextraction potential in Hg-contaminated biosolids from MW-WTP. In addition, the same plant species were germinated and grown in two other substrates (i.e. potting mix and potting mix spiked with mercury(II)). Growth measurements and the mercury uptake for all three substrates were compared. Some plant species grown in potting mix spiked with mercury(II) grew more vigorously than in the other two substrates and showed higher levels of sulphur in their tissues. These results suggested that the mercury stress activated defence mechanisms and it was hypothesised that this was the likely reason for the enhanced production of sulphur compounds in the plant species studied which stimulated their growth. Some species did not grow in biosolids because of the combined effect of high mercury toxicity and high salt content. Atriplex conodocarpa and Australodanthonia caespitose proved to be the most suitable candidates for mercury phytoextraction because of their ability to translocate mercury from roots to the above-ground tissues. PMID:19775810

  20. Potential Selection of Arbuscular Mycorrhizal Fungi (AMF Indigenous Ultisols through the Production of Glomalin

    Directory of Open Access Journals (Sweden)

    Amrizal Saidi

    2014-09-01

    Full Text Available The arbuscular mycorrhizal fungi ( AMF with plants able to increase the capacity of plants to absorb nutrients and water from the soil. Recently, research was indicated that AMF hyphae containing glomalin as a glycoprotein that serves to unify the dispersed soil particles. The content of glomalin in soil is positively correlated with soil aggre- gate stability. The research potential of AMF species indigenous of Ultisol Darmasraya District of West Sumatra and glomalin production in experimental pots of sterile sand medium has been carried out. The purpose of this study was to determine the diversity of AMF species on Ultisol and to seeking indigenous AMF isolates that had the best glomalin production capability. AMF spores were isolated and identified from the rhizosphere soil of corn in Ultisol. AMF species that had been identified experimentally were tested in culture medium pot of sand and zeolite (w / w 1:1 using corn crops. The results found nine of the AMF species indigenous of Ultisol Darmasraya, namely Acaulospora scrobiculata, Glomus etunicatum, Glomus luteum, Glomus mosseae, Glomus verruculosum, Glomus versiforme, Scutellospora gregaria, Scutellospora heterogama and Gigaspora sp. AMF species that showed better colonization ability in corn was G. luteum, G. verruculosum and G. versiforme. All three species produced glomalin significantly higher than the other species, i.e. 1.29 mg g-1; 1.17 mg g-1; 1.15 mg g-1, respectively.

  1. Probiotic potential of selected lactic acid bacteria strains isolated from Brazilian kefir grains.

    Science.gov (United States)

    Leite, A M O; Miguel, M A L; Peixoto, R S; Ruas-Madiedo, P; Paschoalin, V M F; Mayo, B; Delgado, S

    2015-06-01

    A total of 34 lactic acid bacteria isolates from 4 different Brazilian kefir grains were identified and characterized among a group of 150 isolates, using the ability to tolerate acidic pH and resistance to bile salts as restrictive criteria for probiotic potential. All isolates were identified by amplified ribosomal DNA restriction analysis and 16S rDNA sequencing of representative amplicons. Eighteen isolates belonged to the species Leuconostoc mesenteroides, 11 to Lactococcus lactis (of which 8 belonged to subspecies cremoris and 3 to subspecies lactis), and 5 to Lactobacillus paracasei. To exclude replicates, a molecular typing analysis was performed by combining repetitive extragenic palindromic-PCR and random amplification of polymorphic DNA techniques. Considering a threshold of 90% similarity, 32 different strains were considered. All strains showed some antagonistic activity against 4 model food pathogens. In addition, 3 Lc. lactis strains and 1 Lb. paracasei produced bacteriocin-like inhibitory substances against at least 2 indicator organisms. Moreover, 1 Lc. lactis and 2 Lb. paracasei presented good total antioxidative activity. None of these strains showed undesirable enzymatic or hemolytic activities, while proving susceptible or intrinsically resistant to a series of clinically relevant antibiotics. The Lb. paracasei strain MRS59 showed a level of adhesion to human Caco-2 epithelial cells comparable with that observed for Lactobacillus rhamnosus GG. Taken together, these properties allow the MRS59 strain to be considered a promising probiotic candidate. PMID:25841972

  2. Selection of potential cold water marine species for testing of oil dispersants, and chemically dispersed oil

    Energy Technology Data Exchange (ETDEWEB)

    Perkins, R.A. [Alaska Univ., Fairbanks, AK (United States). Dept. of Civil and Environmental Engineering

    2000-07-01

    A study regarding marine species for toxicity testing for Alaska conditions was presented and the potential adverse impacts of a large marine oil spill in cold water were discussed with the objective to determine if the spill should be treated by the use of oil dispersants. Without dispersion, the oil can pollute marine epifauna and can deposit on beaches. The decision to apply dispersants to a marine oil spill requires knowledge of the toxicity of the undispersed oil to pelagic marine life occurring via natural dispersion as opposed to the toxicity of the oil-dispersant mixture. Most standard toxicity tests apply to warm water species. This paper discussed the need to have a standard test species relevant to Alaska waters for toxicity testing. In this study, toxicity testing was done according to the methods of the Chemical Response to Oil Spills : Ecological Effects Research Forum (CROSERF). The testing included capturing adult species in the winter and holding them until larval hatching. Toxicity testing was completed in a narrow time frame before hatching ceased. Many chemical samples were tested. Topsmelt, urchins, shellfish, mysids, copepods, pink salmon fry, and tidepool sculpin were considered by the author to be the most useful for certain types of toxicity testing. 29 refs.

  3. The potential use of an alternative fluid for SFR intermediate loops: selection and first design

    International Nuclear Information System (INIS)

    Among the Generation IV systems, Sodium Fast Reactors (SFR) are promising and benefit of considerable technological experience, but improvements are researched on safety approach and capital cost reduction. One of the main problems to be solved by the standard SFR design is the proper management of the risk of leakage between the intermediate circuit filled with sodium and the energy conversion system using a water Rankine cycle. This risk requires notably an early detection of water leakage to prevent a water-sodium reaction. One innovative solution to this problem is the replacement of the sodium in the secondary loops by an alternative liquid fluid, less reactive with water. This alternative fluid might also allow innovative designs, e.g. intermediate heat exchanger and steam generator grouped in the same component. CEA, Areva NP and EdF have formed a working group in order to evaluate different 'alternative fluids' that might replace sodium. A first selection retained seven fluids on the bases of 'required properties' as: large operating range (low melting point, high boiling point ...), fluid cost and availability, acceptable corrosion at SFR working temperature. These are three bismuth alloys, two nitrate salts, one hydroxide melt and sodium with nanoparticles. Then, it was decided to evaluate these fluids through a multi- criteria analysis in order to point advantages and drawbacks of each fluid and to compare them with sodium. Lack of knowledge, impact on materials, design, working conditions and reactor availability should be emphasized by this analysis, in order to provide sound arguments for a research program on one or two most promising fluids. A global note is given to each fluid by evaluating them with respect to 'grand criteria', weighted differently according to their importance. The grand criteria were: thermal properties, reactivity with structures, reactivity with other fluids (air, water, sodium), chemistry control (including tritium management), safety and waste management, inspection maintenance and repair (ISI and R), impact on components and circuits, availability and cost, level of use. The impact on reactor availability and manageability and the level of knowledge on each fluid were estimated through the former criteria and introduced in the final evaluation as main criteria. The aim of this paper is to present the method of evaluation, the results obtained and the choice that have been made. The impact on design and operation are enhanced for the most promising fluids. It was found that sodium remains the most interesting intermediate fluid. However, Lead Bismuth Eutectic and sodium with nanoparticles also presents some interests and should be further evaluated. (author)

  4. Mediatorless N(2) incorporated diamond nanowire electrode for selective detection of NADH at stable low oxidation potential.

    Science.gov (United States)

    Shalini, Jayakumar; Sankaran, Kamatchi Jothiramalingam; Chen, Huang-Chin; Lee, Chi-Young; Tai, Nyan-Hwa; Lin, I-Nan

    2014-02-21

    The electrocatalytic properties of a N2 incorporated diamond nanowire (N-DNW) unmodified electrode towards the oxidation of nicotinamide adenine dinucleotide (NADH) was critically evaluated. The electrochemical behavior of the N-DNW unmodified electrode was examined and compared with that of boron-doped diamond, glassy carbon electrode, and graphite electrodes. The N-DNW electrode had high selectivity and high sensitivity for the differential pulse voltammetric detection of NADH in the presence of ascorbic acid at the lower and stable oxidation potential. Moreover, it exhibited strong stability after prolonged usage. The oxidation peak potential at the N-DNW electrode remained unchanged even after exposure to the solution, followed by washing, drying, and storage in laboratory air for 20 days, with minimization of surface contamination. Therefore, the N-DNW unmodified electrode shows promise for the detection of NADH and is attractive for use in a dehydrogenase based biosensor and other analytical applications. PMID:24352298

  5. Treeline dynamics with climate change at Central Nepal Himalaya

    Directory of Open Access Journals (Sweden)

    N. P. Gaire

    2013-10-01

    Full Text Available Global climate change has multidimensional impacts with several biological fingerprints, and treeline shifting in tandem with climate change is a widely observed phenomenon in various parts of the world. In Nepal several impacts of climate change on physical environments have been observed. However, studies on the biological impacts are lacking. This dendrochronological study was carried out at the treeline ecotone (3750–4003 m a.s.l. in the Kalchuman Lake (Kal Tal area of the Manaslu Conservation Area in central Nepal Himalaya with the aim to study the dynamic impact of climate change at the treeline. The study provides an insight into regeneration and treeline dynamics over the past 200 yr. Two belt transect plots (size: 20 m wide, >250 m long were laid covering forest line, treeline as well as tree species Abies spectabilis and Betula utilis was done and their tree-cores were collected. Stand character and age distribution revealed an occurrence of more matured B. utilis (max. age 198 yr old compared to A. spectabilis (max. age 160 yr. A. spectabilis contained an overwhelmingly high population (89% of younger plants (A. spectabilis at the rate of 2.61 m yr?1 since 1850 AD. The upper distribution limit of B. utilis was found stagnant in the past few decades. An increment in plant density as well as upward shifting in the studied treeline ecotones was observed. Thus, two species presented species-specific responses to climate change and much wider differences anticipated in their population status as climate continues to cha spectabilis correlated negatively with the mean monthly temperature of May–August of the current year and with September of the previous year. The regeneration of A. spectabilis, on the other hand, was positively related with May–August precipitation and January–April temperature of the current year. The reconstructed average summer temperature (May–August using tree ring data revealed alternate period of cool and warm period with warming in the 2nd half of the 20th century. Further palynological and geochronological studies of sediments of the Kalchuman Lake would advance our understanding of past climatic trends and dynamics of the associated treeline and vegetation in the area.

  6. Potential Sources for Lipid Soluble Food Colorants from Selected Malaysian Traditional Vegetables

    International Nuclear Information System (INIS)

    Colour is one important characteristic to food products as it dictates consumers first perception on the foods flavour and quality. In the current food industry, most of the colorants used were derived from synthetic sources. However, due to negative health impacts of the synthetic colorants, the urgency to find natural colorants and impose it to food products is of great importance. In this study, a group of plant pigments which are potentially introduced as natural food colorants were quantified from 24 species of local traditional vegetables (ulam), characterized as neoxanthin, violaxanthin, lutein, zeaxanthin, β-cryptoxanthine, α-carotene and β-carotene by using HPLC. It was shown that Sauropus androgynous contained the highest amount of neoxanthin, violaxanthin and β-cryptoxanthine at 142.40±3.57, 28.06±0.65 and 0.07±0.00 mg/ g dry weight (DW), respectively. In contrast, highest content of lutein and α-carotene were observed in Centella asiatica at 16.53±0.97 and 2.14±0.12 mg/ g DW, accordingly. Meanwhile, Piper sarmentosum contained the highest zeaxanthin level (123.45±12.3 mg/ g DW) and Oenanthe javanica has the largest amount of β-carotene (3.09±0.06 mg/ g DW). The extracted yellow-to-red lipid soluble pigments can be further developed into commercial food colorant to replace the synthetic colorants in the market thus improving social awareness towards natural products as well as strengthening the national economy. (author)

  7. Mobility of trace elements from selected Australian fly ashes and its potential impact on aquatic ecosystems

    Energy Technology Data Exchange (ETDEWEB)

    Jerzy Jankowski; Colin R. Ward; David French; Sarah Groves [University of New South Wales, Sydney, NSW (Australia). School of Biological, Co-operative Research Centre for Coal in Sustainable Development, Earth and Environmental Sciences

    2006-01-01

    Batch leaching tests have been performed on fly ashes collected from four Australian power stations fuelled by chemically different coals. Two acidic and two alkaline fly ashes were subjected to long-term (144 h) leaching tests, and the behaviour of As, B, Mo and Se was investigated to obtain data on their potential for mobilisation during fly ash-water interactions. All four elements are mobile under different conditions and over different leaching times. The concentrations of these elements released in leaching solutions with initial pH values of 4, 7 and 10 were used to assess the influence of pH conditions on element mobility from the acidic and alkaline fly ashes. The most mobile of the four elements leached were Mo from alkaline fly ashes and B from acidic fly ashes. Arsenic concentration increased with time in leachate solutions from acidic and alkaline fly ashes; however, in solutions in contact with alkaline fly ashes the As concentration, after reaching a maximum, later decreased with time. Selenium mobility shows a similar pattern to that of As, with similar leaching concentrations. Boron has the highest relative mobility of all four elements. A process possibly responsible for the decrease in concentration of B, As and Se in alkaline leaching solutions is the formation of ettringite. Equilibrium between the solid phase (ash) and the leaching solution was not reached in any of the leaching experiments. The pH of the leaching solution is the key factor affecting the mobility of these trace elements in these fly ashes. 50 refs., 9 figs., 4 tabs.

  8. The Potential Use of an Alternative Fluid for SFR Intermediate Loops: Selection and First Design

    International Nuclear Information System (INIS)

    Among the Generation IV systems, Sodium Fast Reactors (SFR) are promising and benefit of considerable technological experience, but improvements are researched on safety approach and capital cost reduction. One of the main problems to be solved by the standard SFR design is the proper management of the risk of leakage between the intermediate circuit filled with sodium and the energy conversion system using a water Rankine cycle. This risk requires notably an early detection of water leakage to prevent a water-sodium reaction, and adequate draining and pressure resistant components to mitigate the reaction consequences. One can think also to suppress this risk by replacing the sodium in the secondary loops by an alternative fluid, less reactive with water. This alternative fluid might also allow innovative designs, e.g. Intermediate Heat eXchanger (IHX) and Steam Generator Unit (SGU) grouped in the same component. CEA, AREVA and EDF have formed a working group in order to evaluate different 'alternative fluids' that might replace sodium. A first selection retained seven fluids on the bases of 'required properties' as: large operating range (low melting point, high boiling point ...), fluid cost and availability, acceptable corrosion at SFR working temperature. These are three bismuth alloys, two nitrate salts, one molten hydroxide and sodium with nanoparticles. Then, it was decided to evaluate these fluids through a multi-criteria analysis in order to point out advantages and drawbacks of each fluid and to compare them with sodium. Lack of knowledge, impact on materials, design, working conditions and reactor availability should be emphasized by this analysis, in order to provide sound arguments for a research program on one or two most promising fluids. A global note is given to each fluid by evaluating them with respect to 'major criteria', weighted differently according to their importance. The major criteria were: thermal properties, reactivity with structures, reactivity with other fluids (air, water, sodium), chemistry control (including tritium management), safety and waste management, In Service Inspection and Repair (ISI and R), impact on components and circuits, availability and cost, level of use. The impact on reactor availability and manageability and the level of knowledge on each fluid were estimated through the former criteria and introduced in the final evaluation as main criteria. The aim of this paper is to present the method of evaluation, the results obtained and the choice that have been made. The impact on design and operation are enhanced for the most promising fluids. It was found that sodium remains the most interesting intermediate fluid regarding all the criteria, and despite its reaction with water. Lead Bismuth Eutectic presents some interests and should be further evaluated. It is however clear that this fluid raises a number of issues, such as corrosion of steel, which would request to lower operating temperature, or to find new materials and then lengthy R and D. (author)

  9. 137Cs in recent tsunami deposits - a potential tracer of selective tsunami sediment entrainment?

    Science.gov (United States)

    Spiske, M.; Bahlburg, H.; Suckow, A.

    2012-12-01

    The tsunami of 27 February, 2010 affected a 600 km long stretch of the central Chilean coastline. We documented the tsunami deposits 4 months after the event in 2010 and two years later in 2012. The broad coastal plain at La Trinchera was inundated ca. 430 m inland and up to 8 m above sea level. A ca. 10 cm thick layer of tsunami sand was deposited on top of marsh sediments. A comparison of this layer in 2010 and 2012 reveals a change in the relative mineral composition and related grain size. In 2010 the layer consisted of 90-93% heavy minerals, 1-4% quartz, 2-3% organics and 1-3% feldspar. In 2012 the relative abundances changed to 63-76% heavy minerals, 10-12% quartz, 16-20% organics and 5-7% feldspar, as a result of the erosion of parts of the finer grained heavy minerals. Furthermore, the thickness decreased to ca. 8 cm. The concentration of the artificial radionuclide 137Cs was recorded using high-resolution gamma-spectrometry. Especially in the northern hemisphere, 137Cs is a tracer for radioactive fallout emitted mainly during nuclear tests in the 1950s to 1960s, peaking around 1963, or nuclear bombing and accidents. In contrast, Cs-concentrations in the southern hemisphere are about four times lower (sediments is higher compared to marine deposits due to Cs-dilution in sea water. For recent (younger than ca. 60 years) onshore tsunami sediments, a mixed Cs-signal is expected because a tsunami can entrain sediments from different depositional environments and different stratigraphic age levels. At La Trinchera, gamma-spectrometry revealed a 137Cs-content of 0.5 Bq/kg for the lower ca. 5 cm of the tsunami layer. The 137Cs-concentration of the upper 5 cm was below the detection limit of 0.1 Bq/kg. Even though the tsunami layer appears to be structureless, the Cs-content may help to distinguish between two distinctive depositional units within the layer. We suggest that the lower part represents reworked onshore deposits with higher Cs-concentrations compared to the upper part that may be composed of material from mainly marine sources. The sediments constituting the upper part of the tsunami deposit may have been stored in shallow marine environments for more than ca. 60 years. Hence, they do not exhibit 137Cs and were not affected by later Cs-fallout because the nuclides were diluted in the sea water. Two transport scenarios for the 2010 Chile tsunami at La Trinchera seem to be possible: 1) The head of an individual onshore flowing wave of the tsunami wave train picked up both beach sand and onshore sediments, whereas the tail entrained shallow marine sediments. As the front of the wave decelerated during its inland flow, these sediments with high Cs-contents were deposited first. Subsequently, marine sediments without a detectable Cs-content reached the shore with some time delay and were then deposited on top. 2) Assuming that a tsunami consists of several waves with different magnitudes, it is possible that an earlier, less energetic wave, entrained sediments onshore, mixed and deposited them. A later, more energetic wave was then able to entrain marine sediments and deposit them on top. Whichever scenario might be more realistic, the Cs-signal may help to document selective, time-dependent erosion and deposition during tsunami inundation.

  10. Predicting Monsoonal-Driven Stream Discharge and Sediment Yield in Himalaya Mountain Basins with Changing Climate and Deforestation

    Science.gov (United States)

    Neupane, R. P.; White, J. D.

    2014-12-01

    Short and long term effects of site water availability impacts the spectrum of management outcomes including landslide risk, hydropower generation, and sustainable agriculture in mountain systems heavily influenced by climate and land use changes. Climate change and land use may predominantly affect the hydrologic cycle of mountain basins as soil precipitation interception is affected by land cover. Using the Soil and Water Assessment Tool, we estimated stream discharge and sediment yield associated with climate and land use changes for two Himalaya basins located at eastern and western margins of Nepal that included drainages of the Tamor and Seti Rivers. Future climate change was modeled using average output of temperature and precipitation changes derived from Special Report on Emission Scenarios (B1, A1B & A2) of 16 global circulation models for 2080 as meteorological inputs into SWAT. Land use change was modeled spatially and included 1) deforestation, 2) expansion of agricultural land, and 3) increased human settlement that were produced by considering current land use with projected changes associated with viability of elevation and slope characteristics of the basins capable of supporting different land use types. We found higher annual stream discharge in all GCM-derived scenarios compared to the baseline with maximum increases of 13 and 8% in SRES-A2 and SRES-A1B for the Tamor and Seti basins, respectively. With 7% of original forest land removed, sediment yield for Tamor basin was estimated to be 65% higher, but increased to 124% for the SRES-B1 scenario. For the Seti basin, 4% deforestation yielded 33% more sediment for the SRES-A1B scenario. Our results indicated that combined effects of future, intensified monsoon rainfall with deforestation lead to dramatic potential for increased stream discharge and sediment yield as rainfall on steep slopes with thin exposed soils increases surface runoff and soil erosion in the Himalayas. This effect appears to be geographically important with higher influence in the eastern Tamor basin potentially due to longer and stronger monsoonal period of that area. Future slope stability and sediment deposition in downstream reservoirs are important future potential vulnerabilities for these basins of which land management plays an important mediating role.

  11. A method for selecting potential geosites. The case of glacial geosites in the Chablais area (French and Swiss Prealps)

    Science.gov (United States)

    Perret, Amandine; Reynard, Emmanuel

    2014-05-01

    Since 2009, an Interreg IVA project (123 Chablais), dealing with the promotion of natural and cultural heritage in the Chablais area, has been developed. It is linked to the creation of the Chablais Geopark. In a context of development of smart forms of tourism, the objective was to develop a strategy promoting the glacial heritage to a wide public in an area where the glaciers have almost disappeared. The recognition of specific places as geoheritage is the result of a double process: a scientific one, based on more or less sophisticated methods, and a social one, that is the acknowledgment by the society. One of the first scientific tasks is to produce a list of "potential geosites" that will be assessed in more details. However, this selection is often a weak point of inventories. It often seems like a "black box" without any transparency. In this project (123 Chablais) we carried out an inventory of glacial geosites, using the method developed by Reynard et al. (2007, 2012). However, a method has been created to enlighten the selection process, and to enhance choices in geoheritage management. As it was not possible to consider all sites in the Chablais area, a mixed selection approach was developed, halfway between completeness and specificity (Martin, 2012). The first step was the creation of a list of "points of interest", established using different sources: literature review, fieldwork and use of GIS to cross information. A selection was then performed according to two criteria: correspondence with a glacial stage (time axis) and belonging to a type of forms (spatial axis). Finally, selected sites aimed at providing a representative overview of the regional glacial witnesses. Therefore, representative sites of the regional geology were selected as well as sites presenting regional peculiarities Temporal and spatial attributes were given to the 101 points of interest identified. From a temporal point of view, this inventory aimed at presenting the main stages of the glacial retreat since the Last Glacial Maximum. From a spatial point of view, the objective was to show the different types of glacial remnants, but also some landforms related to deglaciation processes. Finally, 32 glacial and associated geosites were selected. Each geosite was submitted to a full evaluation process, including basis information, description, explanation of morphogenesis and an evaluation of values assigned to geosites. This assessment, first qualitative, provided valuable information concerning their intrinsic interest and their management. A numerical evaluation was also assessed to classify geosites and define an order of priority for their touristic promotion. It is worth to be noted that each selected points of interest can in fact be qualified as a geosite, using a clear method of selection. In this study, the numerical evaluation is not a mean to select geosites but a way to rank one geosite to another. Some geosites can be abandoned if intrinsic values are too low. Despite a well-defined protocol, the subjectivity and authors' choices are part of the selection process and inventory. This fact is certainly not a weakness. It must be considered whenever such inventory is made. Reference Martin, S. (2012). Valoriser le géopatrimoine par la médiation indirecte et la visualisation des objets géomorphologiques (Thèse de doctorat). Université de Lausanne, Lausanne. Reynard E., Fontana G., Kozlik L., Scapozza C. (2007). A method for assessing the scientific and additional values of geomorphosites, Geographica Helvetica, 62(3), 148-158. Reynard, E., Perret, A., Grangier, L., & Kozlik, L. (2012). Methodological approach for the assessment, protection, promotion and management of geoheritage. EGU General Assembly, Vienna.

  12. [Selection and purification potential evaluation of woody plant in vertical flow constructed wetlands in the subtropical area].

    Science.gov (United States)

    Chen, Yong-Hua; Wu, Xiao-Fu; Hao, Jun; Chen, Ming-Li; Zhu, Guang-Yu

    2014-02-01

    In order to solve the problem that wetland herbaceous plants tend to die during winter in subtropics areas, selection and purification potential evaluation experiments were carried out by introducing into the constructed wetlands 16 species of woody wetland plants. Cluster analysis was performed by including the morphological characteristics, physiological characteristics, as well as nitrogen and phosphorus accumulation of the woody wetland plants. The results indicated that there were significant differences among the tested woody plants in their survival rate, height increase, root length increase and vigor, Chlorophyll content, Superoxide dismutase, Malonaldehyde, Proline, Peroxidase, biomass, average concentration and accumulation of nitrogen and phosphorus. Based on the established evaluation system, the tested plants were clustered into 3 groups. The plants in the 1st group possessing high purification potentials are Nerium oleander and Hibiscus syriacus. Those in the 2nd group possessing moderate purification potentials are Trachycarpus fortune, Llex latifolia Thunb., Gardenia jasminoides, Serissa foetida and Ilex crenatacv Convexa. And those in the 3rd group with low purification potentials are Jasminum udiflorum, Hedera helix, Ligustrum vicaryi, Ligustrum lucidum, Buxus sempervives, Murraya paniculata, Osmanthus fragrans, Mahoniafortune and Photinia serrulata. PMID:24812951

  13. Potential Response to Selection of HSP70 as a Component of Innate Immunity in the Abalone Haliotis rufescens

    Science.gov (United States)

    Brokordt, Katherina B.; González, Roxana C.; Farías, William J.; Winkler, Federico M.

    2015-01-01

    Assessing components of the immune system may reflect disease resistance. In some invertebrates, heat shock proteins (HSPs) are immune effectors and have been described as potent activators of the innate immune response. Several diseases have become a threat to abalone farming worldwide; therefore, increasing disease resistance is considered to be a long-term goal for breeding programs. A trait will respond to selection only if it is determined partially by additive genetic variation. The aim of this study was to estimate the heritability (h2) and the additive genetic coefficient of variation (CVA) of HSP70 as a component of innate immunity of the abalone Haliotis rufescens, in order to assess its potential response to selection. These genetic components were estimated for the variations in the intracellular (in haemocytes) and extracellular (serum) protein levels of HSP70 in response to an immunostimulant agent in 60 full-sib families of H. rufescens. Levels of HSP70 were measured twice in the same individuals, first when they were young and again when they were pre-harvest adults, to estimate the repeatability (R), the h2 and the potential response to selection of these traits at these life stages. High HSP70 levels were observed in abalones subjected to immunostimulation in both the intracellular and extracellular haemolymph fractions. This is the first time that changes in serum levels of HSP70 have been reported in response to an immune challenge in molluscs. HSP70 levels in both fractions and at both ages showed low h2 and R, with values that were not significantly different from zero. However, HSP70 induced levels had a CVA of 13.3–16.2% in young adults and of 2.7–8.1% in pre-harvest adults. Thus, despite its low h2, HSP70 synthesis in response to an immune challenge in red abalone has the potential to evolve through selection because of its large phenotypic variation and the presence of additive genetic variance, especially in young animals. PMID:26529324

  14. Marker-assisted selection as a potential tool for genetic improvement in developing countries: debating the issues

    International Nuclear Information System (INIS)

    Marker-assisted selection (MAS) is a complementary technology, for use in conjunction with more established conventional methods of genetic selection, for plant and animal improvement. It has generated a good deal of expectations, many of which have yet to be realized. Although documentation is limited, the current impact of MAS on products delivered to farmers seems small. While the future possibilities and potential impacts of MAS are considerable, there are also obstacles to its use, particularly in developing countries. Principal among these are issues relating to current high costs of the technology and its appropriateness, given that publicly funded agricultural research in many developing countries is suboptimal and development priorities do not necessarily include genetic improvement programmes. Other potential obstacles to the uptake of MAS in developing countries include limited infrastructure, the absence of conventional selection and breeding programmes, poor private sector involvement and lack of research on specific crops of importance in developing countries. Intellectual property rights may also be an important constraint to development and uptake of MAS in the developing world. It is hoped that through partnerships between developing and developed country institutions and individuals, including public-private sector collaboration, MAS costs can be reduced, resources pooled and shared and capacity developed. With the assistance of the Consultative Group on International Agricultural Research (CGIAR) and international organizations such as FAO, developing countries can benefit more from MAS. These were some of the outcomes of a moderated e-mail conference, entitled 'Molecular Marker- Assisted Selection as a Potential Tool for Genetic Improvement of Crops, Forest Trees, Livestock and Fish in Developing Countries', that FAO hosted at the end of 2003. During the four-week conference, 627 people subscribed and 85 messages were posted, about 60 percent coming from people living in developing countries. Most messages (88 percent) came from people working in research centres (national or international) or universities. The remainder came from people working as independent consultants or from farmer organizations, government agencies, non-governmental organizations (NGOs) or United Nations (UN) organizations. (author)

  15. Violation of the electric dipole selection rules in indirect multiphoton excitation of image potential states on Ag(100)

    International Nuclear Information System (INIS)

    Full text: Photoemission from image potential states (IPS) on Ag(100) is investigated using angle resolved multiphoton photoemission induced by 150 fs laser pulses. For the first time we demonstrate that IPS populated by indirect transitions can be observed with light polarized parallel to the plane of incidence and light polarized normal to the plane of incidence. The latter is a process normally forbidden by the dipole transition selection rules. These findings are related to the creation of a hot electron population. This interpretation is supported by the reduction of the IPS electron effective mass, about 6%, when measured by indirect multiphoton population, followed by one- photon photoemission. The change of the effective mass is attributed to the interaction, with momentum exchange, between the non-equilibrium electron population in the bulk and the IPS. As a result of the momentum exchange the electronic excitations are not restricted anymore by the polarization selection rules. In the figure, panel A, photoemission spectra at hv = 4.28 eV in s and p polarization are shown. The inset represents a schematic energy level diagram at k parallel 0 of Ag(100) surface states, showing a direct one-photon population, two-photon photoemission via the n=1 IPS. In panel B, the spectra at hv 3.14 eV in s and p polarization are shown. In this case a direct population would be forbidden by dipole selection rules in s polarization, hence a indirect mechanism must be invoked

  16. Discovery of potential and selective COX-1 inhibitory leads using pharmacophore modelling, in silico screening and in vitro evaluation.

    Science.gov (United States)

    Balaji, Bhaskar; Hariharan, Sivaram; Shah, Darshit B; Ramanathan, Muthiah

    2014-10-30

    Cyclooxygenase -1 (COX-1) selective inhibitors are anticipated to be potential therapeutic agents for thrombosis, tumorigenesis, atherosclerosis, neuroprotection, and oxidative stress. In this study, a 3D-QSAR pharmacophore model was developed for potent and selective COX-1 inhibition based on 44 compounds from four different scaffolds using Phase, Schrödinger. One (hydrogen-bond) acceptor, one hydrophobic, and two aromatic sites (AHRR) contribute to COX-1 inhibitory activity. Test and decoy sets were used to corroborate the best hypothesis and the validated hypothesis was used to screen the SPECS database. The resultant hits were filtered by standard precision (SP) and extra precision (XP) modes of docking using Glide, Schrödinger which yielded five hits. Free energy calculations were carried out to quantify the affinity differences of the hits towards COX enzymes. These five hits were subjected to in vitro COX (ovine) inhibitory activity studies. The hits displayed potent COX-1 inhibitory activity and good selectivity versus COX-2 enzyme. The compounds also protected the nitric oxide (NO) induced cell death mediated by COX-1 in mouse macrophages cell line. Hence, we hypothesize that these compounds could be promising leads for the design of superior COX-1 inhibitors and insights gained from further exploration of the same could provide pertinent clues for the treatment of the conditions mentioned above. PMID:25203777

  17. Climate Past and Present: A Study on Glaciology of Himalayas in India

    Science.gov (United States)

    Shanmuganandan, S.

    2003-04-01

    Glaciers are moving bodies of ice and snow, which are normally present above the snow line. Glaciers and ice sheets are hundreds to more than one thousand meters thick and change significantly only over decades. On these longer time scales they can influence atmospheric circulation and global sea levels. Glaciers play an important role in maintaining ecosystem stability as they act as buffers and regulate the runoff water supply from high mountains to the plains during both dry and wet spells. The present study is an attempt to analyze the Climate of the Past and Present of the Himalayas with reference to study the glaciology. The study also attempted to use the remote sensed data to explore the past and present situation of glaciology of the Himalayas. Since mountain glaciology of Himalayas played a vital role and stand as an example to explore the possibility of the climate change that occurred from the past to the present and also to determine the status in the future. The Study was based on the secondary and primary data collected from available sources and also collected from various published records to document the evidences for the same. It was observed that the Himalayan glaciers account for about 70% of the world’s non-polar glaciers and affect the lives of millions of people in several countries: China, India, Pakistan, Afghanistan, Nepal and Bangladesh. Their runoff feeds two of the oldest rivers in the world, the Indus and the Ganges, whose tributaries carry precious water for 500 million people on the northern Indian plains. Most of the glaciers in the Himalayas are of a summer-accumulation type, that is major accumulation and ablation take place simultaneously during summer (Fujita et. al, 1997). The glaciers of the Himalayas include some of the longest outside the Polar Regions and reached their largest extent during the end of the last ice age (more than 20,000 years ago). The evidence of these large ice masses can be seen in 'U' shaped valleys, which characterize much of the higher Himalayas. On the basis of their mode of occurrence and dimensions, glaciers have broadly been classified into three categories: valley glaciers, piedmont glaciers and continental glaciers. Himalayan glaciers fall in the category of valley glaciers. It has been estimated that an area of about 32,000 sq. km is under permanent cover of ice and snow in the Himalayas (Negi, 1991). This amounts to about 17% of the total geographical area of the Himalayas. Higher concentration of glaciers in the Himalayas lie in the regions with the highest mountain peaks, that is, Nanga Parbat, Nun Kun, Kinner Kailash, Nanda Devi, Nanda Kot, Annapurna, Mt. Everest, Makalu and Kanchanjunga. There are a number of small, medium and large size glaciers in the Himalayan ranges with typical landform features. Some of the famous and important ones include Baltoro glacier, Gangotari glacier, Gasherbrum glacier, Siachen glacier, Kanchanjunga glacier and Hispar glacier. Of these, the Siachen glacier is the most well known, on account of its strategic significance in the South Asian region. Glaciers are dynamic in nature; they grow and shrink in response to changing climate. During the Pleistocene era (2 million years ago) glaciers occupied about 30% of the total area of the earth as against 10% at present.

  18. 5-Chlorodeoxycytidine when coadministered with modulators of pyrimidine metabolism is an effective and potentially tumor-selective in vivo radiosensitizer

    International Nuclear Information System (INIS)

    5-Chlorodeoxycytidine, a halogenated pyrimidine nucleoside analog, was coadministered with several modulators of pyrimidine metabolism, in order to achieve tumor selective radiosensitization in murine tumor models. The modulators were tetrahydrouridine (an inhibitor of cytidine deaminase), PALA (an inhibitor of aspartate transcarbamylase), 5-fluorodeoxycytidine (which acts to inhibit thymidylate synthetase, and also produces single and double strand breaks in DNA, through incorporation of FdUTP and dUTP into DNA, and subsequent repair) and 5-benzylacyclourindine (an inhibitor of uridine phosphorylase). Several experimental approaches were utilized to determine the extent of tumor radiosensitization and selectivity. Studies measuring the levels of the various metabolites of CldC one hour following CldC administration with or without the various modulators of metabolism showed that it is possible to selectively generate CldU and CldUMP in the tumor compared to normal tissues. DNA incorporation studies measuring the extent of substitution of CldU (derived from CldC) for thymidine also demonstrated the potential for tumor selectivity. Incorporation positively correlated with the levels of cytidine deaminase and dCMP deaminase (two enzymes involved in the metabolism of CldC) in a particular tissue. The levels of these enzymes have been reported to be elevated in many human malignancies. Two model systems were used to assay tumor radiosensitization. The optimum CldC treatment protocol (with tetrahydrouridine, PALA, and 5-fluorodeoxycytidine) yielded a two-fold dose enhancement ratio with the RIF-1 tumor model irradiated in vivo (cell survival was assayed via clonogenic assay). Utilizing the Lewis lung carcinoma model and measuring tumor growth over time, tumor growth was completely arrested for six days following irradiation, with the CldC protocol

  19. Sensitive and selective determination of molybdenum by flow injection chemiluminescence method combined with controlled potential electrolysis technique

    Energy Technology Data Exchange (ETDEWEB)

    Du Jianxiu; Li Jianjun; Yang Lingjuan; Lu Jiuru

    2003-04-03

    A sensitive and selective flow injection chemiluminescence (CL) method combined with controlled potential electrolysis technique was described for the determination of molybdenum. The method is based on the chemiluminescence reaction of luminol with unstable molybdenum(III) in alkaline solution. The molybdenum(III) was on-line reduced from molybdenum(VI) via controlled potential electrolysis technique using a homemade flow-through carbon electrolytic cell at the potential of -0.6 V (versus Ag/AgCl). The method allows the determination of molybdenum in the 5.0x10{sup -10} to 5.0x10{sup -7} g ml{sup -1} range with a limit of detection (3{sigma}) of 5x10{sup -11} g ml{sup -1} molybdenum. The relative standard deviation is 2.6% for the 1.0x10{sup -9} g ml{sup -1} molybdenum solution in 11 repeated measurements. This method was successfully applied to the determination of molybdenum in water samples.

  20. Characterizing the impacts of water resources infrastructure, humans, and hydrologic nonstationarity on changes in flood risk across the Himalaya region

    Science.gov (United States)

    Tullos, D. D.

    2014-12-01

    As flood control infrastructure reaches its design life, and climate change, population growth, and urban migration increase flood risk, the historical paradigm of store-then-release floodwaters behind rigid infrastructure is of decreasing physical and socioeconomic value. Instead, a new paradigm of sustainable flood management is emerging, which can be framed in the context of three elements that can contribute to and/or mitigate flood risk: 1) water resources infrastructure, 2) policies and socioeconomics, and 3) changing climates and land use. In this presentation, I present the results of analysis on the role of these three elements in contributing to flood risk of the Sutlej River (India) and the Koshi River (Nepal) basins for six historical flood events. The Himalaya region was selected based on the a) increasing intensity of monsoonal rains, b) increasing prevalence of glacial lake outburst floods, c) water resources management that achieves short-term development goals but lacks long-term sustainability, and d) other socio-economic, environmental, and geopolitical factors. I develop and apply a flood risk management framework that is based on metrics for characterizing the losses associated with the three elements contributing to major floods in the Himalaya region. Derived from a variety of data sources, results highlight how, across different hydrogeologic settings and various flood magnitudes, the largest influences on high flood losses are associated with inflexible water resources infrastructure and inappropriate development and flood management policies. Particularly for the most destructive events, which are generally associated with landslides and other natural hazards in this region, the effectiveness of some types of traditional and inflexible flood management infrastructure, including large dams and levees, is limited. As opposed to the probability of a particular flood event, findings illustrate the importance of the damages side of the flood risk equation, which is often the most controllable but disregarded element of flood risk management. In addition, results lead to a hypothesized matrix of appropriate flood management strategies for the types of flood events that occur in the hydrogeology and cultural settings of high mountain areas and the lowlands to which they drain.

  1. Geomorphic impacts, age and significance of two giant landslide dams in the Nepal Himalayas: Ringmo-Phoksundo (Dolpo District) and Dhampu-Chhoya (Mustang District).

    Science.gov (United States)

    Fort, Monique; Braucher, Regis; Bourlès, Didier; Guillou, Valery; Nath Rimal, Lila; Gribenski, Natacha; Cossart, Etienne

    2014-05-01

    Large catastrophic slope failures have recently retained much attention in the northern dry Himalayas (1). They play a prominent role in the denudation history of active orogens at a wide range of spatial and time scales (2), and they impact durably landforms and process evolution in upstream catchments. Their occurrence mostly results from three different potential triggers: earthquakes, post-glacial debuttressing, and permafrost melting. We focus on two examples of giant rock slope failures that occurred across and north of the Higher Himalaya of Nepal and assess their respective influence on the regional, geomorphic evolution. The Ringmo rockslide (4.5 km3) results from the collapse of a mountain wall (5148 m) cut into palaeozoic dolomites of the Tethysian Himalayas. It caused the damming of the Suli Gad River at the origin of the Phoksumdo Lake (3600 m asl). The presence of glacial till at the very base of the sequence suggests the rockslide event is post-glacial, a field assumption confirmed by cosmogenic dating. Two consistent 36Cl ages of 20,885 ±1675 argue for a single, massive event of paraglacial origin that fits well with the last chronologies available on the Last Glacial Maximum in the Nepal Himalaya. The persistence of the Phoksumdo Lake is due to its dam stability (i.e. high lime content of landslide components) and to low sediment flux from the arid, upper Suli Gad catchment. The Dhampu-Chhoya rock avalanche (about 1 km3, area extent 10 km2) was derived from the northward failure of the Kaiku ridge, uphold by north-dipping, upper crystallines of the Higher Himalaya. It dammed the Kali Gandaki River, with complex interactions with the Late Pleistocene ice tongues derived from the Dhaulagiri (8167 m) and Nilgiris (7061 m) peaks. Both the rock avalanche and glaciers controlled the existence and level of the "Marpha Lake" (lacustrine deposits up to Kagbeni). Again, consistent 10Be ages of 29,680 ± 1015 ka obtained from two large blocks (>1000 m3) suggest a single event, in full agreement with other 10Be dates obtained by a different team from the same site (3). This latter event occurred during glaciation, and was likely triggered in connection with the North Himalayan Fault and/or Thakkhola fault activity. Post-landslide dam evolution includes rapid dissection of lacustrine deposits (4), yet the braided pattern of the Kali Gandaki evidence the delay in headward erosion caused by landslide dam persistence. References: (1) Hewitt K., 2009. Catastrophic rock slope failures and late Quaternary developments in the Nanga Parbat-Haramosh Massif, Upper Indus basin, northern Pakistan. Quaternary Science Reviews, 28, 1055-1069; (2) Korup, O., Clague, J.J., 2009. Natural hazards, extreme events, and mountain topography. Quaternary Science Reviews 28, 977-990; (3) Zech R., Zech M, Kubik P.W., Kharki K., Zech W. (2009). Deglaciation and landscape history around Annapurna, Nepal, based on 10Be surface exposure dating, Quaternary Science Reviews, v. 28(11-12), pp.1106-1118; (4) Fort M., Cossart E. (2013) Erosion assessment in the middle Kali Gandaki (Nepal): A sediment budget approach. Journal of Nepal Geological Society, Vol. 46, pp. 25-40.

  2. Land use changes in Himalaya and their impacts on environment, society and economy: A study of the Lake Region in Kumaon Himalaya, India

    Science.gov (United States)

    Tiwari, Prakash

    2008-11-01

    The traditional resource use structure in Himalaya has transformed considerably during the recent past, mainly owing to the growth of population and the resultant increased demand of natural resources in the region. This transformation in resource use practices is particularly significant in the densely populated tracts of Himalaya. As a result, cultivated land, forests, pastures and rangelands have been deteriorated and depleted steadily and significantly leading to their conversion into degraded and non-productive lands. These rapid land use changes have not only disrupted the fragile ecological equilibrium in the mountains through indiscriminate deforestation, degradation of land resources and disruption of the hydrological cycle, but also have significant and irreversible adverse impacts on the rural economy, society, livelihood and life quality of mountain communities. It has been observed that the agricultural production has declined, water sources are drying up fast due to decreased ground water recharge and a large number of villages are facing enormous deficit of critical resources, such as food, fodder, firewood and water, mainly due to unabated deforestation. As a result, the rural people, particularly the women, have to travel considerably long distances to collect fodder and firewood and to fetching water. It is therefore highly imperative to evolve a comprehensive and integrated land use framework for the conservation of the biophysical environment and sustainable development of natural resources in Himalaya. The land use policy would help local communities in making use of their natural resources scientifically and judiciously, and thus help in the conservation of the biophysical environment and in the increasing of the productivity of natural resources. The study indicates that conservation of forests and other critical natural resources through community participation, generation of alternative means of livelihood, and employment in rural areas can help increase rural income as well as restore ecosystem services.

  3. The role of spatial selective attention in working memory for locations: evidence from event-related potentials.

    Science.gov (United States)

    Awh, E; Anllo-Vento, L; Hillyard, S A

    2000-09-01

    We investigated the hypothesis that the covert focusing of spatial attention mediates the on-line maintenance of location information in spatial working memory. During the delay period of a spatial working-memory task, behaviorally irrelevant probe stimuli were flashed at both memorized and nonmemorized locations. Multichannel recordings of event-related potentials (ERPs) were used to assess visual processing of the probes at the different locations. Consistent with the hypothesis of attention-based rehearsal, early ERP components were enlarged in response to probes that appeared at memorized locations. These visual modulations were similar in latency and topography to those observed after explicit manipulations of spatial selective attention in a parallel experimental condition that employed an identical stimulus display. PMID:11054925

  4. Genetic Issues of Some of the Non Metallic Minerals in Lesser Himalaya

    Directory of Open Access Journals (Sweden)

    R. Sharma

    2010-10-01

    Full Text Available A brief account of the representative and workable industrial minerals namely magnesite, talc and barite in Lesser Himalaya, is presented here emphasizing their genesis. Deposits of magnesite and talc are found associated with Neoproterozoic, plateform type, shelf-slope limestone-dolomite host rocks from inner Lesser Himalayan sequences. Field, textural, geochemical signatures and fluid inclusions trapped in dolomite and magnesite reveal within basin processes, in an increased burial- diagenetic environment responsible for formation of magnesite replacing dolomite. Talc is formed at the expense of magnesite and silica, and with limited dolomite involvement at transition conditions from diagenetic to metamorphism. Barite deposit is hosted within Neoproterozoic Nagthat quartzite rocks of outer Lesser Himalaya, wherein its textures, fluid inclusion, sulfur and strontium isotopic studies helped in genetic understanding.

  5. Role of vegetation in modulating denudation and topography across the Himalaya

    Science.gov (United States)

    Olen, Stephanie; Bookhagen, Bodo; Strecker, Manfred

    2015-04-01

    Studies of Himalayan denudation, to date, have primarily focused on the effects of lithology, tectonic activity, and climate in shaping landscape and controlling denudation rates. Climate can impact denudation not only through increased precipitation, runoff, or glaciation, but also via its role in controlling vegetation cover. Since the classical study of Langbein and Schumm [1958] emphasizing the role of vegetation cover in determining erosional efficiency, theoretical and plot-scale studies have highlighted the role of vegetation on surface processes [Collins et al., 2004; Istanbulluoglu and Bras, 2005; Collins and Bras, 2010; Carretier et al., 2013; Jeffery et al., 2014]. Vegetation cover and density vary considerably in the Himalaya, both across and along strike. Across strike, vegetation transitions from dense forest and agriculturally-used plots in the Lesser Himalaya to sparse alpine and arid, virtually non-vegetated regions at high elevation and in the rain shadow north of the Higher Himalaya peaks. Along-strike vegetation densities also differ significantly and show a pronounced E-W gradient. To quantify the along-strike vegetation gradient, we use 14 years of MODIS 13C1 enhanced vegetation index (EVI) data to calculate mean annual, summer (MJJASO), and winter (NDJFMA) for the entire Himalaya. Additionally, we calculate a differential EVI that compares summer versus winter vegetation density (MJJASO/NDJFMA). A decrease in vegetation density is observed from east to west, with the greatest difference in winter vegetation cover (225% higher in the eastern than western Himalaya). In contrast, differential EVI is higher in the western Himalaya, increasing 170% from east to west. To evaluate the effect of vegetation on denudation and landscape evolution, we combine the 14-year EVI data, topographic analysis, and a compilation of >100 published and unpublished 10-Be terrestrial cosmogenic nuclide (TCN) catchment-mean denudation rates from across the Himalaya [Godard et al., 2014; Portenga et al., 2014; Scherler et al., 2014; Olen et al., submitted]. We calculate the relationship between various topographic metrics (e.g. mean basin slope, normalized channel steepness [ksn]) and the TCN catchment-mean denudation of non-glaciated fluvial watersheds from previously published and submitted studies. The variation in vegetation density between study sites correlates with the relationship between topography and denudation in each region. In sparsely vegetated areas, denudation increases in a rapid, non-linear fashion as topographic metrics such as the normalized channel steepness (ksn) or mean basin hillslope increase. Where vegetation cover is denser, the relationship between denudation and topography becomes increasingly linear, such that lower denudation rates are maintained as hillslopes and channels steepen. Additionally, more sparsely vegetated regions appear to reach a maximum steepness lower than that observed in densely vegetated regions. We therefore observe a negative correlation between increasing annual, summer, and winter EVI and the power-law exponent p of the relationship denudation ? (topographic metric)p; and a positive correlation between p and differential EVI. In contrast to recent studies arguing that Himalayan denudation is primarily forced by tectonics, our study emphasizes how vegetation density, as a climatic agent, modulates erosional style and landscape development along strike across the Himalaya. Carretier, S., et al. (2013), Slope and climate variability control of erosion in the Andes of central Chile, Geology, 41(2), 195-198. Collins, D. B. G., and R. L. Bras (2010), Climatic and ecological controls of equilibrium drainage density, relief, and channel concavity in dry lands, Water Resources Research, 46(4), W04508. Collins, D. B. G., R. L. Bras, and G. E. Tucker (2004), Modeling the effects of vegetation-erosion coupling on landscape evolution, Journal of Geophysical Research: Earth Surface, 109(F3), F03004. Godard, V., D. L. Bourlés, F. Spinabella, D. W. Burbank, B. Bookhagen, G. B. F

  6. Comaparison of late pleistocene glacier extensions along a meridian Himalaya transect by geomorphological and pedological methods

    Science.gov (United States)

    Wagner, M.

    2009-04-01

    There is still a controverse discussion on Late Pleistocene glacier extensions for many parts of the Himalaya. Besides differing geomorphological results, more recent pedological relative datings of moraines delivered further inconsistent findings. For a meridian Himalaya transect along the Kali Gandaki a detailed field review of these different glaciogeomorphological reconstructions has been carried out, supplemented by new equilibrium line altitude (ELA) calculations. In a second step these findings have been used as benchmark to explore the options and limits of pedological relative dating of glacigene accumulations in the Higher Himalaya. A review of the already existing glaciogeomorphological results clearly appoved the more extended glaciation and the detailed relative chronology found in Kuhle (1982), while the more restricted glaciation view advanded by Fort (2000) is the result of foulty and missing geomorphological interpretations. To reconstruct former ELA depressions within the very steep and highly dynamic landforms of the Himalaya, „Toe-To-Summit-Altitude-Methods" (TSAM) are most adequate. Only the upper and lower glacier margin need to be known, which can be identified quite certain even for pre-existing glacier extensions. The method Kuhle is proved to provide the most suitable results, because the strong influence of the valley topography and the degree of debris cover on the position of the ELA within the vertical extension of the glacier can be simulated by the „factor of snowline deviation" (FSD). Maximum ELA depressions of 1300 to 1500 m can be observed for the south-face of the Higher Himalaya as well as for the arid north-face and the Inner Himalaya. The extreme topographical changeover arising from the inflow of the former glaciers from the tributary valleys into the wide and flat valley bottoms lead to little uncertainness, but the relative chronology of the glacier stages can certainly be derived. Most of the granulometric weathering indices are inapplicable as relative dating methods because of the typically high textural variability within till deposits. On the other hand around the central mountain range crossing section of the Kali Gandaki most of the pedochemical weathering indices mirror the relative chronology of deglaciation correctly, since comparable soil development conditions can be found. Thereby not only a differentiation between the High-, Late-, and Neoglacial is possible, but also within the Late Glacial. North of the Himalaya main range, only a few very certain pedochemical relative dating methods are applicable as a consequence of the drier climatic conditions. South of the Higher Himalaya variations of the parent material and the for the southern slope typical characteristics, e.g., a high degree of relief energy, precipitation, and anthropogenic use, preclude a reliable deduction of the relative age of the glacigenic accumulations from the soil age, since a required undisturbed soil development and primary form conservation of the accumulations, is nearly impossible.

  7. Photographic Key for the Microhistological Identification of Some Plants of Indian Trans-Himalaya

    Directory of Open Access Journals (Sweden)

    Tanveer AHMED

    2015-06-01

    Full Text Available Microhistology techniques have been used in many studies regarding food habits of herbivores. The absence of detailed reference materials and time consumed in creating reference plant materials for a particular study species and area hampers an understanding and extensive use of the technique. On the other hand, the use of direct sighting procedure of animals to study the dietary spectrum of herbivores is interrupted by tough terrain and harsh climatic condition in the Trans-Himalaya. The current study provides a photographic key for identification of 38 plants species belonging to 35 genera and 21 families. Structures such as types of stomata, trichomes and epidermal cells are discussed for different species of plants collected from Kargil, Ladakh. The given information is expected to help researchers working on feeding ecology of mammals in the Indian Trans-Himalaya.

  8. Distribution and Potential Mobility of Selected Heavy Metals in a Fluvial Environment Under the Influence of Tanneries

    Directory of Open Access Journals (Sweden)

    Rodrigues M. L. K.

    2013-04-01

    Full Text Available In this study we evaluated the occurrence of heavy metals in a fluvial environment under the influence of tanneries – the Cadeia and Feitoria rivers basin (RS, south Brazil, highlighting the distribution and potential mobility of the selected elements. Every three months, over one year-period, selected heavy metals and ancillary parameters were analyzed in water and sediment samples taken at ten sites along the rivers. Water analyses followed APHA recommendations, and sediment analyses were based on methods from USEPA (SW846 and European Community (BCR sequential extraction. The determinations were performed by ICP/OES, except for Hg (CV/ETA. Statistical factor analysis was applied to water and sediment data sets, in order to obtain a synthesis of the environmental diagnosis. The results revealed that water quality decreased along the rivers, and mainly on the dry period (January, showing the influence of tannery plants vicinity and flow variations. Except for Fe, Al, and eventually Mn, heavy metal contents in water were in agreement with Brazilian standards. Concerning sediments, Al, Cu, Fe, Ni, Mn, Ti, and Zn concentrations appeared to reflect the base levels, while Cr and Hg were enriched in the deposits from the lower part of the basin. The partition of heavy metals among the sediment geochemical phases showed higher mobility of Mn along the sampling sites, followed by Cr in the lower reach of the basin, most affected by tanneries. Since Cr was predominantly associated to the oxidizable fraction, its potential mobilization from contaminated sediments would be associated to redox conditions. The detection of Hg in the tissue of a bottom-fish species indicated that the environmental conditions are apparently favoring the remobilization of this metal from contaminated sediments.

  9. Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies

    Indian Academy of Sciences (India)

    N. Johns; B. H. Tan; M. Macmillan; T. S. Solheim; J. A. Ross; V. E. Baracos; S. Damaraju; K. C. H. Fearon

    2014-12-01

    Cancer cachexia is a complex and multifactorial disease. Evolving definitions highlight the fact that a diverse range of biological processes contribute to cancer cachexia. Part of the variation in who will and who will not develop cancer cachexia may be genetically determined. As new definitions, classifications and biological targets continue to evolve, there is a need for reappraisal of the literature for future candidate association studies. This review summarizes genes identified or implicated as well as putative candidate genes contributing to cachexia, identified through diverse technology platforms and model systems to further guide association studies. A systematic search covering 1986–2012 was performed for potential candidate genes / genetic polymorphisms relating to cancer cachexia. All candidate genes were reviewed for functional polymorphisms or clinically significant polymorphisms associated with cachexia using the OMIM and GeneRIF databases. Pathway analysis software was used to reveal possible network associations between genes. Functionality of SNPs/genes was explored based on published literature, algorithms for detecting putative deleterious SNPs and interrogating the database for expression of quantitative trait loci (eQTLs). A total of 154 genes associated with cancer cachexia were identified and explored for functional polymorphisms. Of these 154 genes, 119 had a combined total of 281 polymorphisms with functional and/or clinical significance in terms of cachexia associated with them. Of these, 80 polymorphisms (in 51 genes) were replicated in more than one study with 24 polymorphisms found to influence two or more hallmarks of cachexia (i.e., inflammation, loss of fat mass and/or lean mass and reduced survival). Selection of candidate genes and polymorphisms is a key element of multigene study design. The present study provides a contemporary basis to select genes and/or polymorphisms for further association studies in cancer cachexia, and to develop their potential as susceptibility biomarkers of cachexia.

  10. Monitoring of High Mountain Glaciers in the Vicinity of Everest (Himalaya) using Remote Sensing Capability

    Science.gov (United States)

    Thakuri, S.; Salerno, F.; Bolch, T.; Smiraglia, C.; Tartari, G.

    2014-12-01

    Himalayan glaciers are of crucial interest due to their role in the cryospheric system and hydrology. This contribution examines glacier changes between 1960s and 2013 using satellite data. The study is focused in 3 basins in Nepal: Upper Sun Koshi (USKB; 2850 km2), Dudh Koshi (DKB; 3720 km2), and Tamor (TB; 5875 km2). We observed an overall glacier surface loss of 0.19 ± 0.26 % a-1 (146.1 to 136.9 km2) in SKB for 1975-2013 period; 0.27 ± 0.06 % a-1 (404.6 to 351.8 km2) in the DKB for 1962-2011, and 8.4% (0.25 ± 0.29 % a-1; 610.9 to 559.3 km2) in the TB for 1975-2009 period. In the DKB, we observed an upward shift of snow-line altitude (?SLA) by more than 180 m, a terminus retreat of on average ~ 400 m, and an increase of 17.6 ± 3.1% in debris coverage between 1962 and 2011. Moreover, we observed that (i) glaciers with increased debris cover have experienced a reduced termini retreat; (ii) negative mass balances (i.e., ?SLA) induce increases of debris coverage; (iii) slight, but statistically insignificant acceleration of the surface area loss since early 1990s; but a significant loss for the largest glaciers (>10 km2) that have accumulation zones at higher elevations and along the preferable south-north direction of the monsoon; (iv) a significant ?SLA; moreover, the largest glaciers present median ?SLA that are nearly double than that of the smallest; this finding leads to a hypothesis that these glaciers are shrinking, not only due to warming temperatures, but also as a result of decreasing precipitation due to a weakening Asian monsoons registered over the last few decades. Furthermore, we present first results on the geodetic glacier mass and velocity changes of selected glaciers, and climatic trends. In fact, less accumulation due to the observed decrease of precipitation should cause lower glacier flow velocity until to the ice stagnation of tongues as observed by other previous studies in the region. Finally, we compared our findings with other studies in the high mountain Asia and conclude that the shrinkage of these glaciers are less than that of western and eastern Himalaya, and southern and eastern Tibetan Plateau. The location in higher elevations have likely reduced the impact of warming on these glaciers, but have not been excluded from a relentlessly continuous and slow recession process over the past 50 yrs.

  11. Potential social, institutional, and environmental impacts of selected energy-conservation measures in two Washington communities. [Seattle and Yakima

    Energy Technology Data Exchange (ETDEWEB)

    Edelson, E.; Olsen, M.

    1980-03-01

    The likely environmental, social, and institutional impacts of selected energy-conservation measures in two communities in Washington state are reported. The five conservation measures investigated in this study were: (1) retrofitting existing buildings; (2) district heating and Integrated Community Energy Systems (ICES); (3) small automobiles and vehicle redesign; (4) land-use and housing modifications; and (5) electric-utility rate reform. Twenty potential impact areas were selected for analysis. These areas were divided into five categories of environmental impacts, economic impacts, community impacts, personal impacts, and overall quality of life in the community. The research was conducted in Seattle and Yakima, Washington. In each location, about two dozen public officials and business, labor, and community leaders were interviewed. Their diverse views are summarized. The Seattle respondents saw energy conservation as a highly desirable policy with a number of temporary, transitional problems arising as energy-conservation measures were implemented. Yakima respondents, in contrast, did not expect to encounter many serious energy problems in the foreseeable future and consequently viewed energy conservation as a relatively minor community concern. Moreover, they anticipated that many conservation measures, if implemented by the government, would encounter either apathy or resistance in their community. Two broad generalizations can bedrawn from these interviews: (1) energy conservation will basically be beneficial for the natural environment and our society; and (2) if energy conservation does become a dominant thrust in our society, it could stimulate and reinforce a much broader process of fundamental social change. (LCL)

  12. Origin and radiative forcing of black carbon transported to the Himalayas and Tibetan Plateau

    Directory of Open Access Journals (Sweden)

    M. Kopacz

    2010-09-01

    Full Text Available The remote and high elevation regions of central Asia are influenced by black carbon (BC emissions from a variety of locations. BC deposition contributes to melting of glaciers and questions exist, of both scientific and policy interest, as to the origin of the BC reaching the glaciers. We use the adjoint of the GEOS-Chem model to identify the location from which BC arriving at a variety of locations in the Himalayas and Tibetan Plateau originates. We then calculate its direct and snow-albedo radiative forcing. We analyze the seasonal variation in the origin of BC using an adjoint sensitivity analysis, which provides a detailed map of the location of emissions that directly contribute to black carbon concentrations at receptor locations. We find that emissions from northern India and central China contribute the majority of BC to the Himalayas, although the precise location varies with season. The Tibetan Plateau receives most BC from western and central China, as well as from India, Nepal, the Middle East, Pakistan and other countries. The magnitude of contribution from each region varies with season and receptor location. We find that sources as varied as African biomass burning and Middle Eastern fossil fuel combustion can significantly contribute to the BC reaching the Himalayas and Tibetan Plateau. We compute radiative forcing in the snow-covered regions and estimate the forcing due to the BC induced snow-albedo effect at about 5–15 W m?2 within the region, an order of magnitude larger than radiative forcing due to the direct effect, and with significant seasonal variation in the northern Tibetan Plateau. Radiative forcing from reduced snow albedo accelerates glacier melting. Our analysis can help inform mitigation efforts to slow the rate of glacial melt by identifying regions that make the largest contributions to BC deposition in the Himalayas and Tibetan Plateau.

  13. Mechanisms and timescales of felsic magma segregation, ascent and emplacement in the Himalaya

    OpenAIRE

    B. Scaillet; Searle, MP

    2006-01-01

    We combine field, petrological, geochemical and experimental observations to evaluate the timescales of compaction-driven and shear-assisted melt extraction and ascent in the Himalaya. The results show that melt migration via compaction and channelling is inescapable and operates on timescales of less than 1 million years and possibly as short as 0.1 million years. Field and petrological data show that such a fast and efficient melt transfer results from a combination of favourable factors, i...

  14. Seasonal precipitation, river discharge, and sediment flux in the western Himalaya

    OpenAIRE

    Wulf, Hendrik

    2011-01-01

    Rainfall, snow-, and glacial melt throughout the Himalaya control river discharge, which is vital for maintaining agriculture, drinking water and hydropower generation. However, the spatiotemporal contribution of these discharge components to Himalayan rivers is not well understood, mainly because of the scarcity of ground-based observations. Consequently, there is also little known about the triggers and sources of peak sediment flux events, which account for extensive hydropower reservoir f...

  15. Pictorial keys for predominant Bactrocera and Dacus fruit flies (Diptera: Tephritidae) of north western Himalaya

    OpenAIRE

    C. S. Prabhakar; Pankaj Sood; Mehta, P. K.

    2012-01-01

    A pictorial key for 13 species of fruit flies under 2 genera namely Bactrocera and Dacus of subfamily Dacinae (Diptera: Tephritidae) is presented in this paper based on actual photographs of fruit flies collected from north western Himalaya of India during 2009-2010. Among these, Bactrocera diversa (Coquillett), Bactrocera scutellaris (Bezzi), Bactrocera tau (Walker), Bactrocera cucurbitae (Coquillett), Bactrocera zonata (Saunders), Bactrocera correcta (Bezzi), Bactrocera dorsalis (Hendel), B...

  16. Hydrological response to climate change in a glacierized catchment in the Himalayas

    OpenAIRE

    Immerzeel, Walter W.; van Beek, L. P. H.; M. Konz; Shrestha, A. B.; Bierkens, M.F.P.

    2011-01-01

    The analysis of climate change impact on the hydrology of high altitude glacierized catchments in the Himalayas is complex due to the high variability in climate, lack of data, large uncertainties in climate change projection and uncertainty about the response of glaciers. Therefore a high resolution combined cryospheric hydrological model was developed and calibrated that explicitly simulates glacier evolution and all major hydrological processes. The model was used to assess the future deve...

  17. Seasonal succession of crustacean zooplankton in Wular Lake of the Kashmir Himalaya

    OpenAIRE

    Shah Javaid Ahmad; Pandit Ashok Kumar

    2013-01-01

    The present study was undertaken on Wular Lake, a Ramsar Site in Kashmir Himalaya, to study the seasonal succession of crustacean zooplankton from September 2010 to August 2011. A total of 42 crustacean taxa belonging to Cladocera (23), Copepoda (16) and Ostracoda (3) were identified at five different sampling sites. Among the crustaceans, Cladocera was numerically the most dominant group at sites III, IV and V, followed by Copepoda at sites I and II. On an average basis total crustacea...

  18. Study of attenuation mechanism for Garwhal–Kumaun Himalayas from analysis of coda of local earthquakes

    OpenAIRE

    Mukhopadhyay, S.; Department of Earth Sciences, IIT Roorkee, Roorkee, Uttaranchal 247667, India; Sharma, J.; 70/11-A, Purvawali Ganesh Chowk, Roorkee-247667, India; Del Pezzo, E.; Istituto Nazionale di Geofisica e Vulcanologia, Sezione OV, Napoli, Italia; Kumar, N.; Wadia Institute of Himalayan Geology, General Mahadeo Singh Road, Dehradun-248001, India

    2010-01-01

    The relative contribution of intrinsic (Q?1 i ) and scattering (Q?1 s ) attenuation to seismic wave attenuation was estimated for the Garwhal–Kumaun Himalayas using Multiple Lapse Time Window Analysis (MLTWA) method under the assumption of isotropic scattering. Local earthquake data recorded by an array operated by Wadia Institute of Himalayan Geology (WIHG), India was used for this purpose. It is observed that scattering attenuation primarily contributes to seismic wave att...

  19. Structure and Function of Shisham Forests in Central Himalaya, India: Dry Matter Dynamics

    OpenAIRE

    LODHIYAL, NEELU; LODHIYAL, L. S.; Pangtey, Y. P. S.

    2002-01-01

    The biomass and net primary productivity (NPP) of 5? to 15?year?old Shisham (Dalbergia sissoo Roxb.) forests growing in central Himalaya were estimated. Allometric equations were developed for all above? and below?ground components of trees and shrubs for each stand. Understorey forest floor biomass and litter fall were also estimated in forest stands. The biomass (dry matter), forest floor biomass (standing crop litter), tree litter fall and NPP of trees and shrubs increased with increasi...

  20. Assessment, prevention and mitigation of landslide hazard in the Lesser Himalaya of Himachal Pradesh

    Directory of Open Access Journals (Sweden)

    Patra Punyatoya

    2015-09-01

    Full Text Available Landslides are destructive geological processes that have globally caused deaths and destruction to property worth billion dollars. Landslide occurrences are widespread and prolific in India covering more than 15 per cent of the total area. These are mostly concentrated in the Himalayan belt, parts of Meghalaya Plateau, Nilgiri Hills, Western and Eastern Ghats. The slope failure in the hilly terrain is due to geological processes and events. The frequency and magnitude of slope failure also increased due to anthropogenic activities such as road construction, deforestation and urban expansion. Keeping all these problems in mind research focuses on the Lesser Himalaya of Himachal Himalaya as it falls under very high risk zone in case of landslides and comprise of three objectives. They are: a to analyse the spatial pattern of landslides in the Lesser Himalaya, b to assess the causes of landslides vulnerability in the study region and c to suggests some preventive measures to mitigate landslides. In this work an attempt has been made to collect data on landslides incidences and damage from the secondary sources like Geological Survey of India, Building Material and Technology Promotion council from Ministry of Urban Affairs. The methodologies adopted for data analysis are simple tabulations, bar diagrams, statistical and mapping techniques to represent the Landslide vulnerability of the Lesser Himalaya. The analysis of the study reveals that there is increase in the number of landslides. The spatial pattern of landslide shows linear patterns, viz. along roads, rivers or lineaments/ faults. Besides, heavy rainfall, floods and earthquakes enhance the vulnerability condition. The landslides may be part and parcel of the Himalayan landscape, but they can be mitigated by some suitable measures. Few methods of landslide prevention in the study region have been suggested.

  1. High Mountain Melt-Down:Local Perceptions of Global Warming in the Andes and Himalayas

    OpenAIRE

    Lamadrid, Armando José

    2008-01-01

    Present scientific knowledge about global warming affirms that ice and snow packs in the high mountains of the world are melting at increasing rates (see IPCC 2007 and UNEP 2007). Melting glaciers and receding snowlines jeopardize seasonal stream and river systems in arid regions of the world and threaten the livelihood of farmers who utilize the meltwater for irrigation. This study contrasts two case studies in the Himalayas of Nepal and the Central Andes of Perú to gauge the impacts of thes...

  2. Treeline and vegetation dynamics in response to environmental changes in Nepal, the central Himalaya

    OpenAIRE

    Shrestha, Krishna Babu

    2013-01-01

    Aims: To describe and evaluate patterns of vegetation response to ongoing environmental changes across climate-limited (alpine treeline ecotone) and humanmodified (temperate Himalayan oak forests) ecosystems in Nepal, central Himalaya.

    Methods: I used dendroclimatological techniques to examine spatial and temporal changes in tree growth responses (paper I) and recruitment patterns (paper II) to climatic variability across a dry ...

  3. Responses of Montane Forest to Climate Variability in the Central Himalayas of Nepal

    OpenAIRE

    Janardan Mainali; John All; Pramod Kumar Jha; Dinesh Raj Bhuju

    2015-01-01

    Climate changes are having dramatic ecological impacts in mid- to high-latitude mountain ranges where growth conditions are limited by climatic variables such as duration of growing season, moisture, and ambient temperature. We document patterns of forest vegetative response for 5 major alpine forest communities to current climate variability in the central Himalayas of Nepal to provide a baseline for assessment of future changes, as well as offer some insight into the trajectory of these cha...

  4. Black Carbon Flux Across the Himalaya through the Kali Gandaki Valley in Nepal

    Science.gov (United States)

    Dhungel, S.; Panday, A. K.; Mahata, K. S.

    2013-12-01

    Significant increases in black carbon concentration have been observed in the recent years over the Indo-Gangetic plain, the foothills of the Himalaya, as well as the high Himalaya and the Tibetan Plateau. The concentration of increased black carbon can be significantly correlated to the albedo effect and the warming of atmosphere at high altitudes due to the deposition of black carbon in the snow clad mountains. It is hypothesized that this deposition contributes to increased melting of Himalayan glaciers and snowfields. Satellite images show increasing amounts of aerosol haze over the Indo-Gangetic plains which penetrate into the Himalayan valleys. But how does it reach the high altitude of the Himalayan cryosphere? To date, mechanisms of transport upwind of the valley from the Indo-Gangetic plains up to the Himalaya have not been thoroughly investigated. We hypothesize that wind systems in the deep river valleys that cut across the Himalaya, such as the Arun valley and Kali Gandaki valley, serve as important pathways for pollutant transport. In 2010 the University of Virginia, in collaboration with ICIMOD and Nepal Wireless, established an atmospheric research station in Jomsom, Nepal (28.78N, 83.42E, 2900 m.a.s.l.). The station is equipped to measure black carbon (BC), carbon monoxide (CO), and ozone concentrations. It also has an automated weather station, a filter sampler, and a NASA Aeronet Sunphotometer. Here we use our observations in Jomsom to present an estimate of the annual flux of black carbon from the Indo-Gangetic plains to the Tibetan Plateau through the Kali Gandaki valley. In this way, we gain insight into the significance of deep valleys and their role as pathways for pollutant transport.

  5. Biodiversity Conservation through Traditional Beliefs System: A Case Study from Kumaon Himalayas, India

    OpenAIRE

    Singh, Harsh; Tariq HUSAIN; Priyanka AGNIHOTRI; Puran Chandra PANDE; Iqbal, Mudassar

    2012-01-01

    The present study was carried out in Malay Nath sacred grove of Kumaon Himalaya, India, in appreciation of its role in biodiversity conservation. The whole grove is dedicated to the local deity “Malay Nath”, and showing semi-temperate type vegetation of the region. Rituals and cultural beliefs of the local peoples of Kumaon are plays significant role in conserving biodiversity. The study aimed at the documentation and inventory of the sacred grove, its phytodiversity, threats and conservatio...

  6. Sustainability Perspectives of Development in Leh District (Ladakh, Indian Trans-Himalaya): an Assessment

    OpenAIRE

    PELLICIARDI, VLADIMIRO

    2012-01-01

    This thesis deals with a human inhabited territory in the Indian Trans-Himalaya: the Leh District, in Ladakh, at a “crossroad of high Asia”, geographically classified “cold desert”. For many centuries the local population has led a self-reliant existence mainly based upon subsistence agriculture, pastoralism and caravan trade. Modernization, due to governmental programs, and the progressive opening to external influence and resources – i.e. globalization – characterize the current development...

  7. Probing orographic controls in the Himalayas during the monsoon using satellite imagery

    OpenAIRE

    Barros, A. P.; Kim, G; Williams, E; Nesbitt, S W

    2004-01-01

    The linkages between the space-time variability of observed clouds, rainfall, large-circulation patterns and topography in northern India and the Himalayas were investigated using remote sensing data. The research purpose was to test the hypothesis that cloudiness patterns are dynamic tracers of rainstorms, and therefore their temporal and spatial evolution can be used as a proxy of the spatial and temporal organization of precipitation and precipitation processes in the Himalayan range duri...

  8. Similarities and differences of aerosol optical properties between southern and northern slopes of the Himalayas

    OpenAIRE

    Xu, C; Ma, Y. M.; Yang, K; Zhu, Z. K.; Wang, J. M.; P. M. Amatya; Zhao, L.

    2013-01-01

    The Himalayas is located at the southern edge of the Tibetan Plateau, and it acts as a natural barrier for the transport of atmospheric aerosols, e.g. from the polluted regions of South Asia to the main body of the Tibetan Plateau. In this study, we investigate the seasonal and diurnal variations of aerosol optical properties measured at the three Aerosol Robotic Network (AERONET) sites over the southern (Pokhara station and EVK2-CNR station in Nepal) and northern (Qomolangma (Mt. Everes...

  9. Precipitation and snow cover in the Himalaya: from reanalysis to regional climate simulations

    OpenAIRE

    Ménégoz, M.; Gallée, H.; Jacobi, H. W.

    2013-01-01

    We applied a Regional Climate Model (RCM) to simulate precipitation and snow cover over the Himalaya, between March 2000 to December 2002. Due to its higher resolution, our model simulates a more realistic spatial variability of wind and precipitation than those of the reanalysis used as boundary conditions. In this region, we found very large discrepancies between the estimations of precipitation provided by reanalysis, rain gauges networks, satellite observations, and our RCM simulat...

  10. ECOLOGICAL STATUS AND IMPACT OF DISTURBANCE IN AN ALPINE PASTURE OF GARHWAL HIMALAYA, INDIA

    OpenAIRE

    MANOJ DHAULAKHANDI; GOVIND S. RAJWAR; MUNESH KUMAR

    2010-01-01

    The alpine area in Garhwal Himalaya is highly fragile and is known for its beautiful flora and fauna. The study area was located just below the Gangotri glacier which is the origin of Bhagirathi, a holy river of India. Pilgrimage, tourism, adventure activities and mules are the factors responsible for causing disturbance in this area. There is a remarkable variation in the values of diversity, species richness, dominance, density IVI and biomass production at Bhojbasa Protected (BP) and Bhojb...

  11. EVALUATION OF ANTIMICROBIAL PROPERTIES OF TERRESTRIAL ORCHIDS (COLLECTED FROM NORTHERN HIMALAYAS) AGAINST CERTAIN HUMAN PATHOGENS

    OpenAIRE

    Amit Bharal*, Manila Kashyap, Vipan Kumar Sohpal and Jaspreet Kaur Sembi

    2014-01-01

    The four main varieties of orchids, collected from northern Himalayas (Tara devi and Chhrabra forests, Shimla, HP) were evaluated for their antimicrobial activity against human pathogenic bacteria. The ethanol and methanol extracts of Cypripedium cordigerum and Malaxis acuminata were found to be highly active against both P.aeruginosa and S.aureus with minimal microbial static concentration (MIC) in the range of 100mg/ml. These plants particularly demonstrated antimicrobial properties against...

  12. Taxonomic status of Bupleurum (Apiaceae) in outer hills of Kashmir Himalayas, India

    OpenAIRE

    B. L. Bhellum

    2012-01-01

    Introduction: The genus Bupleurum is perennial rhizomatous herbs, recognized by simple leaves,conspicuous bracts and bractlets, often shows a great deal of variation in morphological characteristics. The genus is well developed in temperate and alpine zones of Kashmir Himalayas and other lesser Himalayan ranges of Jammu and Kashmir State. A key to the species, brief description, flowering and fruiting periods are given. The approximate elevation, distribution of species in the region andillus...

  13. Longest time series of glacier mass changes in the Himalaya based on stereo imagery

    OpenAIRE

    Bolch, T.; Pieczonka, T; Benn, D.I.

    2010-01-01

    Mass loss of Himalayan glaciers has wide-ranging consequences such as declining water resources, sea level rise and an increasing risk of glacial lake outburst floods (GLOFs). The assessment of the regional and global impact of glacier changes in the Himalaya is, however, hampered by a lack of mass balance data for most of the range. Multi-temporal digital terrain models (DTMs) allow glacier mass balance to be calculated since the availabi...

  14. Phylogeography of microbial phototrophs in the dry valleys of the high Himalayas and Antarctica

    OpenAIRE

    Schmidt, S K; Lynch, R. C.; King, A. J.; Karki, D.; Robeson, M. S.; L. NAGY; Williams, M. W.; Mitter, M. S.; Freeman, K. R.

    2010-01-01

    High-elevation valleys in dry areas of the Himalayas are among the most extreme, yet least explored environments on Earth. These barren, rocky valleys are subjected to year-round temperature fluctuations across the freezing point and very low availability of water and nutrients, causing previous workers to hypothesize that no photoautotrophic life (primary producers) exists in these locations. However, there has been no work using modern biogeochemical or culture-independent molecular methods...

  15. Origin and radiative forcing of black carbon transported to the Himalayas and Tibetan Plateau

    Directory of Open Access Journals (Sweden)

    M. Kopacz

    2011-03-01

    Full Text Available The remote and high elevation regions of central Asia are influenced by black carbon (BC emissions from a variety of locations. BC deposition contributes to melting of glaciers and questions exist, of both scientific and policy interest, as to the origin of the BC reaching the glaciers. We use the adjoint of the GEOS-Chem model to identify the location from which BC arriving at a variety of locations in the Himalayas and Tibetan Plateau originates. We then calculate its direct and snow-albedo radiative forcing. We analyze the seasonal variation in the origin of BC using an adjoint sensitivity analysis, which provides a detailed map of the location of emissions that directly contribute to black carbon concentrations at receptor locations. We find that emissions from northern India and central China contribute the majority of BC to the Himalayas, although the precise location varies with season. The Tibetan Plateau receives most BC from western and central China, as well as from India, Nepal, the Middle East, Pakistan and other countries. The magnitude of contribution from each region varies with season and receptor location. We find that sources as varied as African biomass burning and Middle Eastern fossil fuel combustion can significantly contribute to the BC reaching the Himalayas and Tibetan Plateau. We compute radiative forcing in the snow-covered regions and find the forcing due to the BC induced snow-albedo effect to vary from 5–15 W m−2 within the region, an order of magnitude larger than radiative forcing due to the direct effect, and with significant seasonal variation in the northern Tibetan Plateau. Radiative forcing from reduced snow albedo likely accelerates glacier melting. Our analysis may help inform mitigation efforts to slow the rate of glacial melt by identifying regions that make the largest contributions to BC deposition in the Himalayas and Tibetan Plateau.

  16. Seasonal precipitation, river discharge, and sediment flux in the western Himalaya

    OpenAIRE

    Wulf, Hendrik

    2012-01-01

    Rainfall, snow-, and glacial melt throughout the Himalaya control river discharge, which is vital for maintaining agriculture, drinking water and hydropower generation. However, the spatiotemporal contribution of these discharge components to Himalayan rivers is not well understood, mainly because of the scarcity of ground-based observations. Consequently, there is also little known about the triggers and sources of peak sediment flux events, which account for extensive hydropower reservoir f...

  17. Glacial Lake Expansion in the Central Himalayas By Landsat Images, 1990-2010

    Science.gov (United States)

    Nie, Y.; Liu, Q.; Liu, S.

    2014-12-01

    Glacial lake outburst flood (GLOF) is a serious hazard in high, mountainous regions. In the Himalayas, catastrophic risks of GLOFs have increased in recent years because most Himalayan glaciers have experienced remarkable downwasting under a warming climate. However, current knowledge about the distribution and recent changes in glacial lakes within the central Himalaya mountain range is still limited. Here, we conducted a systematic investigation of the glacial lakes within the entire central Himalaya range by using an object-oriented image processing method based on the Landsat Thematic Mapper (TM) or Enhanced Thematic Mapper (ETM) images from 1990 to 2010. We extracted the lake boundaries for four time points (1990, 2000, 2005 and 2010) and used a time series inspection method combined with a consistent spatial resolution of Landsat images that consistently revealed lake expansion. Our results show that the glacial lakes expanded rapidly by 17.11% from 1990 to 2010. The pre-existing, larger glacial lakes, rather than the newly formed lakes, contributed most to the areal expansion. The greatest expansions occurred at the altitudinal zones between 4800 m and 5600 m at the north side of the main Himalayan range and between 4500 m and 5600 m at the south side, respectively. Based on the expansion rate, area and type of glacial lakes, we identified 67 rapidly expanding glacial lakes in the central Himalayan region that need to be closely monitored in the future. The warming and increasing amounts of light-absorbing constituents of snow and ice could have accelerated the melting that directly affected the glacial lake expansion. Across the main central Himalayas, glacial lakes at the north side show more remarkable expansion than those at the south side. An effective monitoring and warning system for critical glacial lakes is urgently needed.

  18. Permutations of Rajput identity in the West Himalayas, c. 1790-1840

    OpenAIRE

    Moran, Arik; Dr David Washbrook

    2010-01-01

    ?The sustained interaction of local elites and British administrators in the West Himalayas over the decades that surrounded the early colonial encounter (c. 1790-1840) saw the emergence of a distinctly new understanding of communal identity among the leaders of the region. This eventful period saw the mountain ('Pahari') kingdoms transform from fragmented, autonomous polities on the fringes of the Indian subcontinent to subjects of indigenous (Nepali, Sikh) and, ultimately,...

  19. One Dimensional Reference velocity model and precise locations of earthquake hypocenters in the Central Himalaya

    Science.gov (United States)

    Rai, S. S.; Perugu, M.; Krishnavajjhala, S.; Paul, A.; Parimi, R.; Gupta, S.; Gaur, V. K.

    2011-12-01

    We report a well constrained velocity model of the Central (Kumaon-Garhwal) Himalaya, based on a rigorous analysis of over 5,000 seismograms generated at 50 digital broadband seismic stations in the region between April 2005 and June 2008. These include data from 385 local earthquakes with azimuth gaps of less than 180°, each of which had a minimum of 7P and 5S phase readings. This velocity model was then used to map the locations of 1150 earthquakes of magnitude between 1 and 5, that occurred in the region during the recording period.A majority of these occur in the upper 20 km of the crust and form a 50 km wide band along the surface trace of the Main Central Thrust, as first shown by Gaur et al.(1984). However, we also find another parallel band of earthquakes about 70 km to its southwest, and a significant number both in the Tethys Himalaya and within the flexed crust of the under-thrusting Indian plate beneath the Ganga basin, notably along an arc-normal band through Chamoli which has witnessed two moderate earthquakes (of magnitude more than 5 ) over the past dozen years. Furthermore, unlike the reported absence of seismicity (Monsalve et al. 2006) in the lower crust of Nepal Himalaya, and its reappearance in the shallow mantle, the Central Himalayan crust is found to be seismically active throughout, with no event reliably recorded in the shallow mantle of this region during the epoch of our seismic recording.

  20. Water level changes of high altitude lakes in Himalaya–Karakoram from ICESat altimetry

    Indian Academy of Sciences (India)

    Priyeshu Srivastava; Rakesh Bhambri; Prashant Kawishwar; D P Dobhal

    2013-12-01

    Himalaya–Karakoram (H–K) region hosts large number of high altitude lakes but are poorly gauged by in-situ water level monitoring method due to tough terrain conditions and poor accessibility. After the campaigns of ICESat during 2003–2009, now it is possible to achieve lake levels at decimetre accuracy. Therefore, in present study, high altitude lake levels were observed using ICESat/GLAS altimetry in H–K between 2003 and 2009 to generate baseline information. The study reveals that out of 13 lakes, 10 lakes show increasing trend of water levels at different rate (mean rate 0.173 m/y) whereas three lakes unveiled decreasing trend (mean rate ?0.056 m/y). Out of five freshwater lakes, four lakes show an increasing trend of their level (mean rate 0.084 m/y) whereas comparatively six salt lakes (out of seven salt lakes) exhibited ?3 times higher mean rate of lake level increase (0.233 m/y). These observed lake level rise can be attributed to the increased melt runoffs (i.e., seasonal snow and glacier melts) owing to the enhanced mean annual and seasonal air temperature during past decade in north-western (NW) Himalaya. Further, varied behaviours of lake level rises in inter- and intra-basins suggest that the local climatic fluctuations play prominent role along with regional and global climate in complex geographical system of NW Himalaya.

  1. Tree ring inferred summer temperature variations over the last millennium in western Himalaya, India

    Energy Technology Data Exchange (ETDEWEB)

    Yadav, Ram Ratan [Birbal Sahni Institute of Palaeobotany, Lucknow (India); Braeuning, Achim [University of Erlangen-Nuremberg, Institute of Geography, Erlangen (Germany); Singh, Jayendra [University Greifswald, Ecosystem Dynamics, Institute of Botany and Landscape Ecology, Greifswald (Germany)

    2011-04-15

    We report the first millennium-long reconstruction of mean summer (May-June-July-August) temperature extending back to AD 940 derived from tree-ring width data of Himalayan pencil juniper (Juniperus polycarpos C. Koch) from the monsoon-shadow zone in the western Himalaya, India. Centennial-scale variations in the reconstruction reveal periods of protracted warmth encompassing the 11-15th centuries. A decreasing trend in mean summer temperature occurred since the 15th century with the 18-19th centuries being the coldest interval of the last millennium, coinciding with the expansion of glaciers in the western Himalaya. Since the late 19th century summer temperatures increased again. However, current warming may be underestimated due to a weakening in tree growth-temperature relationship noticeable in the latter part of the 20th century. Mean summer temperature over the western Himalaya shows a positive correlation with summer monsoon intensity over north central India. Low-frequency variations in mean summer temperature anomalies over northwestern India are consistent with tree-ring inferred aridity in western North America. These far-distance linkages reported here for the first time underscore the utility of long-term temperature records from the western Himalayan region in understanding global-scale climatic patterns. (orig.)

  2. Topographic position of large slope failures revealed by excess topography in the Himalaya-Karakoram Ranges

    Science.gov (United States)

    Blöthe, Jan; Korup, Oliver; Schwanghart, Wolfgang

    2015-04-01

    Large slope failures (defined here as affecting >0.1 km² in planform area) substantially contribute to denuding hillslopes, thereby limiting the growth of topographic relief in active mountain belts produced by tectonic uplift and fluvial or glacial incision. The region around Nanga Parbat, situated in the Himalaya-Karakoram ranges (HKR), has been shown to exhibit one of the largest clusters of large scale slope failure known. However, a thorough analysis of the pattern of landslides in the wider region, let alone an inventory of large slope failure is lacking. We take this as a motivation to create a landslide inventory covering the upper Indus catchment located in the HKR of NW India and N Pakistan. Our data set contains 492 large landslides that we compiled from published studies and mapping from remote sensing imagery. Using an empirical volume-area scaling approach we estimate the total landslide volume at >250 km³. This is more than thousand times the contemporary annual sediment load in the Indus River. We analyse the distribution of these landslides with respect to the regional hypsometry, contemporary glacier cover, and the distribution of rock glaciers. We further introduce excess topography ZE, which quantifies the vertical column of rock material above a hypothetical failure plane, as a first-order metric of potentially unstable rock slopes. We find that large bedrock landslides in the HKR preferentially detach near or from below the study area's median elevation, while glaciers and rock glaciers occupy higher elevations almost exclusively. This picture is supported by the distribution of excess topography ZE that peaks along major fluvial and glacial inner gorges, which is where the majority of large rock-slope failures occur. Our analysis suggests a hitherto unrecognised vertical layering of denudation processes, with landslides chiefly operating below the median elevation, whereas mass transport in higher elevations seems to be dominated by glaciers and rock glaciers, or high-frequency low-magnitude failure (<<0.1 km2). Whatever causes this pattern, the distinct position of excess topography ZE and large bedrock landsliding challenge the notion of widespread threshold hillslopes in the HKR. We therefore conclude that hillslope adjustment to fluvial and glacial incision along inner gorges through large-scale rock-slope failures is protracted and far from exhausted.

  3. Relative importance of fluvial and glacial erosion in shaping the Chandra Valley, western Himalaya, India

    Science.gov (United States)

    Eugster, Patricia; Thiede, Rasmus C.; Scherler, Dirk; Codilean, Alexandru T.; Strecker, Manfred

    2013-04-01

    Although glaciers are often believed to be the principal erosional agents and the cause for increasing the relief of mountain belts, quantifying their contribution to long-term erosion and exhumation is challenging. This is particularly true for the Himalaya, where present-day ice coverage is relatively high, but evidence for extensive glaciations in the past more limited, presumably due to high erosion rates that quickly remove the depositional and geomorphic evidence of glacial impacts. Previous work indicates that the Chandra Valley, in the headwaters of the Chenab River, was strongly glaciated during the Quaternary. In addition, existing thermochronological data suggest a large change in exhumation rates along the valley. This change spatially corresponds to a major fluvial knickpoint, the joining of several large glaciers, a lithological break, and a steep precipitation gradient. In this study we determine spatial and temporal variations in valley incision through fluvial and glacial erosion on different timescales by using cosmogenic radionuclide (CRN) dating of glacially-carved and striated surfaces, various low-temperature thermochronometers, and morphometric analysis. Knickzones are found at elevations of ~3900 m asl along several tributaries of the Chandra/Chenab valleys and other valleys throughout Lahul, potentially indicating a causal relationship with glacial processes. Our field observations and preliminary CRN data suggest major glacial occupation of the Chandra Valley, particularly by the Bara Shigri Glacier, prior to 14 ka. Our data also confirm former CRN measurements in that area. We hypothesize that these observations coincide with the glacially carved surface of the valley, which indicates a minimum altitude of ~4100 m asl for glaciation in the lower Chandra Valley. Here, glacial carving has been the first-order erosional agent during the Quaternary. Furthermore, published AFT cooling ages are young below an elevation of 4100 m asl and increase strongly in the upper part of the valley above this elevation and the observed knickpoints, suggesting slower erosional exhumation in the more arid upper Chandra Valley. The ultimate goal of this study is to better understand the regional erosion pattern within the Chandra Valley, and to possibly determine whether glaciers influenced by local conditions (tectonics, climate), impede or accelerate erosion.

  4. Geochemical characterization of supraglacial debris via in situ and optical remote sensing methods: a case study in Khumbu Himalaya, Nepal

    Directory of Open Access Journals (Sweden)

    K. A. Casey

    2012-01-01

    Full Text Available Surface glacier debris samples and field spectra were collected from the ablation zones of Nepal Himalaya Ngozumpa and Khumbu glaciers in November and December 2009. Geochemical and mineral compositions of supraglacial debris were determined by X-ray diffraction and X-ray fluorescence spectroscopy. This composition data was used as ground truth in evaluating field spectra and satellite supraglacial debris composition and mapping methods. Satellite remote sensing methods for characterizing glacial surface debris include visible to thermal infrared hyper- and multispectral reflectance and emission signature identification, semi-quantitative mineral abundance indicies and spectral image composites. Satellite derived supraglacial debris mineral maps displayed the predominance of layered silicates, hydroxyl-bearing and calcite minerals on Khumbu Himalayan glaciers. Supraglacial mineral maps compared with satellite thermal data revealed correlations between glacier surface composition and glacier surface temperature. Glacier velocity displacement fields and shortwave, thermal infrared false color composites indicated the magnitude of mass flux at glacier confluences. The supraglacial debris mapping methods presented in this study can be used on a broader scale to improve, supplement and potentially reduce errors associated with glacier debris radiative property, composition, areal extent and mass flux quantifications.

  5. Great paleoearthquakes of the central Himalaya and their implications for seismotectonic models and seismic hazard assessment

    Science.gov (United States)

    Yule, D.; Lave, J.; Kumar, S.; Wesnousky, S.

    2007-12-01

    A growing body of paleoseismic data collected from more than ten sites in Nepal and India has documented large coseismic displacements at the thrust front (Main Frontal thrust (MFT)). Three great earthquakes have been identified: in ~A.D. 1410 centered north of Delhi, in A.D. 1505 centered in far-western Nepal, and in ~A.D. 1100 centered in eastern Nepal. It is noteworthy that wherever exposures of the MFT have been studied estimates of surface slip are consistently large; with a range of 9-26 m. Historic accounts of the 1505 earthquake describe strong shaking across a 600-km-long stretch of the central Himalaya. A magnitude for this event is estimated to be >Mw 8.5 based on the maximum extent of felt strong shaking, the 100 km width of the locked portion of the basal detachment, and an average slip of 10-15 m. Though no historic accounts exist for the ~1410 and ~1100 earthquakes, the similarity between their surface expression and the 1505 rupture suggests that these events may have been equally large. These surface-rupturing earthquakes are distinctly different from a host of blind thrust events (Mw 7.5-8.4) that dominate the historic record since A.D. 1505. Both blind and emergent earthquakes are presumed to rupture the basal detachment and release interseismic strain that accumulates near the base of the High Himalaya and carry it to the thrust front where Holocene shortening occurs at rates of 15-22 mm/yr. Whereas the surface-rupturing earthquakes clearly deform the thrust front, survey data from the region affected by the 1906 Dehra Dun earthquake suggest that blind events contribute negligible, if any, deformation to the frontal structures. The factors controlling whether or not surface rupture occurs on the MFT remain unconstrained, but the current data seem to suggest that >Mw 8.5 surface-rutpuring earthquakes are the primary contributors to the shortening observed at the thrust front. It is sobering to consider that the 'Big One' has not struck the Himalaya in over 500 years and that Mw 7.5-8.4 earthquakes are the 'moderate' earthquakes'. Further study to constrain the lateral extent and recurrence of the great paleoearthquakes of the central Himalaya is critical to answer important questions about the Himalaya earthquake cycle and the seismic hazard facing the rapidly urbanizing population of the region.

  6. Interpretation of observed ground level changes due to the 1905 Kangra earthquake, Northwest Himalaya

    Science.gov (United States)

    Chander, Ramesh

    1988-06-01

    The Kangra earthquake of 1905 in the Northwest Himalaya was the first Indian earthquake for which coseismic ground elevation changes were measured through repeat precision levelling. The levelling Une from Saharanpur to Mussoorie via Dehra Dun was situated near the southeastern extremity of the NW-SE trending meizoseismal area. Maximum uplift of 14.3 cm was measured at a bench mark in Dehra Dun. Some details of the levelling data having been published recently, data for eight bench marks were considered for interpretation in this study. In principle, these are sufficient for us to estimate eight parameters of a rectangular rupture buried in a homogeneous Poisson solid. But because of some uncertainties regarding the bench mark positions and also the relatively small amounts of uplift measured at the bench marks, we have preferred to use the data as a means to check the reasonableness of rupture models proposed on other grounds rather than to propose a new model independently. The observed elevation changes are not in accord with the view that the Kangra earthquake was caused by a single 100 km long rupture along the Shahpur-Mandi sector of the Northwest Himalaya. However, the data can be explained if, in addition, a second smaller rupture extending on either side of the levelling Une near Dehra Dun is assumed. The data can also be explained if the rupture during the earthquake had (1) a length of 280 km parallel to the general strike of the Himalaya from around Kangra up to a short distance (about 10-15 km) northwest of the levelling Une near Dehra Dun, (2) a breadth of 80 km perpendicular to the strike of the Himalaya, (3) a northeasterly dip of about 5°, and (4) a depth of 10-15 km along its SW edge. Finally, the elevation data rule out any role for the Main Boundary Thrust in the occurrence of the Kangra earthquake. This major tectonic feature demarcating the geological boundary between the outer and the lesser Himalaya thus appears to be unimportant in the current seismotectonics of the region and the subduction of the Indian lithospheric plate under the mountains.

  7. Lower Paleozoic Continuity of the East Gondwanan Margin and Implications for Interpretation of Tectonostratigraphic Zones of the Himalaya

    Science.gov (United States)

    Myrow, P.; Hughes, N.; Fanning, C. M.; Banerjee, D.; Dipietro, J. A.

    2009-12-01

    Qualitative and quantitative study of the tectonic and erosional history of the Himalayan orogen requires knowledge of the geology prior to major unroofing. Our studies of sedimentary successions in the Lesser (LH) and Tethyan Himalaya (TH)support depositional and stratigraphic continuity of the lower Paleozoic Indian Gondwanan margin across the various lithotectonic zones of the Himalaya, and along strike, from beyond the western Himalayan syntaxis in Pakistan, to Arunachal Pradesh, adjacent to the eastern syntaxis. Across-strike continuity is supported by (1) the presence of a distinctive Cambrian-Permian unconformity in the Salt Range (south of the Main Boundary Thrust), LH of India, and northern Tethyan part of Pakistan, and (2) correlative Neoproterozoic diamictite units in both the TH and LH. In addition, lithofacies changes support northward deepening across the northern Indian margin from the LH to the TH. Cambrian rocks extended south of the MBT in the Salt Range of Pakistan and are also exposed on cratonic India, south of the Himalayan Frontal Thrust in the Marwar basin of Rajasthan. Correlations indicate that the Neoproterozoic-Cambrian blanket extended far onto the Indian craton, just as on other paleocontinents at this time. Along-strike stratigraphic relationships also support the existence this extensive blanket, from which the outer Lesser Himalaya is a remnant. Similarities in stratigraphic successions, depositional ages, and geochemical deposits (e.g., phosphate) of the LH and TH between the central Himalaya and Pakistan, as well as correlative Neoproterozoic carbonate in Arunachal Pradesh (Buxa Formation), indicate that this blanket extended from west of the western syntax of the Himalaya across to the eastern syntaxis. Detrital zircon age spectra from Cambrian and Ordovician samples across the ancient northern Indian Himalayan margin show uniform signatures that include age ranges from Archean to Ordovician, with dominant of 1.3-0.9 Ga, ~0.7-0.54 Ga, and ~ 0.5 Ga peaks. New detrital zircon age data are presented for three Cambrian deposits: (1) the Tethyan Cambrian Tanawal Formation from the Peshwar Basin, Pakistan, north of the P-K Fault (=MCT), (2) cratonic Indian strata of the Tunklian Sandstone of Rajasthan, and (3) the Quartzite Formation of the Pele La Group of the Black Mountains of Bhutan. The detrital age spectra of these samples match those from Cambrian deposits across the central Himalaya. Thus, these new detrital spectra, in combination with stratigraphic data, demonstrate the continuity of lowermost Paleozoic strata along and across the Himalaya. Such continuity requires similar stratigraphic architecture in the LH, TH, and Greater Himalaya prior to Cenezoic deformation, and requires considerable removal of Neoproterozoic through Cambrian strata from the Lesser Himalaya during Himalayan uplift.

  8. Contemporary deformation in the Kashmir-Himachal, Garhwal and Kumaon Himalaya: significant insights from 1995-2008 GPS time series

    Science.gov (United States)

    Jade, Sridevi; Mukul, Malay; Gaur, V. K.; Kumar, Kireet; Shrungeshwar, T. S.; Satyal, G. S.; Dumka, Rakesh Kumar; Jagannathan, Saigeetha; Ananda, M. B.; Kumar, P. Dileep; Banerjee, Souvik

    2014-06-01

    We present new insights on the time-averaged surface velocities, convergence and extension rates along arc-normal transects in Kumaon, Garhwal and Kashmir-Himachal regions in the Indian Himalaya from 13 years of high-precision Global Positioning System (GPS) time series (1995-2008) derived from GPS data at 14 GPS permanent and 42 campaign stations between and . The GPS surface horizontal velocities vary significantly from the Higher to Lesser Himalaya and are of the order of 30 to 48 mm/year NE in ITRF 2005 reference frame, and 17 to 2 mm/year SW in an India fixed reference frame indicating that this region is accommodating less than 2 cm/year of the India-Eurasia plate motion (). The total arc-normal shortening varies between along the different transects of the northwest Himalayan wedge, between the Indo-Tsangpo suture to the north and the Indo-Gangetic foreland to the south indicating high strain accumulation in the Himalayan wedge. This convergence is being accommodated differentially along the arc-normal transects; in Lesser Himalaya and 3-4 mm/year in Higher Himalaya south of South Tibetan Detachment. Most of the convergence in the Lesser Himalaya of Garhwal and Kumaon is being accommodated just south of the Main Central Thrust fault trace, indicating high strain accumulation in this region which is also consistent with the high seismic activity in this region. In addition, for the first time an arc-normal extension of has also been observed in the Tethyan Himalaya of Kumaon. Inverse modeling of GPS-derived surface deformation rates in Garhwal and Kumaon Himalaya using a single dislocation indicate that the Main Himalayan Thrust is locked from the surface to a depth of over a width of 110 km with associated slip rate of . These results indicate that the arc-normal rates in the Northwest Himalaya have a complex deformation pattern involving both convergence and extension, and rigorous seismo-tectonic models in the Himalaya are necessary to account for this pattern. In addition, the results also gave an estimate of co-seismic and post-seismic motion associated with the 1999 Chamoli earthquake, which is modeled to derive the slip and geometry of the rupture plane.

  9. Analysis of wind speed data and wind energy potential in three selected locations in south-east Nigeria

    Energy Technology Data Exchange (ETDEWEB)

    Oyedepo, Sunday O. [Covenant Univ., Ota, Ogun State (Nigeria). Mechanical Engineering Dept.; Adaramola, Muyiwa S. [Norwegian Univ. of Science and Technology, Trondheim (Norway). Dept. of Energy and Process Engineering; Paul, Sunday S. [Manitoba Univ., Winnipeg, MB (Canada). Dept. of Mechanical and Manufacturing Engineering

    2012-07-01

    In this study, the wind speed characteristics and energy potential in selected three locations in south eastern part of Nigeria were investigated using wind speed data that span between 24 and 37 years measured at 10m height. It was shown that the annual mean wind speed at height of 10 m for Enugu, Owerri, and Onitsha are 5.42 m/s, 3.36 m/s, and 3.59 m/s, respectively, while the annual mean power densities are, respectively, 96.98 W/m2, 23.23 W/m2 and 28.34 W/m{sup 2}. It was further shown that the mean annual value of the most probable wind speed are 5.47m/s, 3.72m/s and 3.50m/s for Enugu, Owerri and Onitsha, respectively, while the respective annual value of the wind speed carrying maximum energy 6.48m/s, 4.33m/s, and 3.90m/s.The performance of selected commercial wind turbine models (with rated power between 50kW and 1000kW) designed for electricity generation and a windmill (rated power of 0.36kW) for water pumping located in these sites were examined.The annual energy output and capacity factor for these turbines as well as the water produced by the windmill were determined. The minimum required design parameters for a wind turbine to be a viable option for electricity generation in each location are also suggested. (orig.)

  10. Potential Roles of the Interaction Between Model V1 Neurons with Orientation-Selective and Non-selective Surround Inhibition in Contour Detection

    Directory of Open Access Journals (Sweden)

    Kai-Fu Yang

    2015-06-01

    Full Text Available Both the neurons with orientation-selective and with non-selective surround inhibition have been observed in the primary visual cortex (V1 of primates and cats. Though the inhibition coming from the surround region (named as non-classical receptive field, nCRF has been considered playing critical role in visual perception, the specific role of orientation-selective and non-selective inhibition in the task of contour detection is less known. To clarify above question, we first carried out computational analysis of the contour detection performance of V1 neurons with different types of surround inhibition, on the basis of which we then proposed two integrated models to evaluate their role in this specific perceptual task by combining the two types of surround inhibition with two different ways. The two models were evaluated with synthetic images and a set of challenging natural images, and the results show that both of the integrated models outperform the typical models with orientation-selective or non-selective inhibition alone. The findings of this study suggest that V1 neurons with different types of center-surround interaction work in cooperative and adaptive ways at least when extracting organized structures from cluttered natural scenes. This work is expected to inspire efficient phenomenological models for engineering applications in field of computational machine-vision.

  11. The potential influence of far-infrared emission lines on the selection of high-redshift galaxies

    CERN Document Server

    Smail, Ian; Ivison, R J; Ibar, E

    2011-01-01

    We investigate whether strong molecular and atomic emission lines at far-infrared wavelengths can influence the identification and derived properties of galaxies selected from broad-band, far-infrared or submillimetre observations. Several of these lines, e.g. [CII]158um, have been found to be very bright in some high-redshift galaxies, with fluxes of >0.1-1% of the total far-infrared luminosity, and may be even brighter in certain populations at high redshifts. At redshifts where these lines fall in instrument pass-bands they can significantly increase the broad-band flux measurements. We estimate that the contributions from line emission could boost the apparent broad-band flux by >20-40% in the Herschel and SCUBA-2 bands. Combined with the steep source counts in the submillimetre and far-infrared bands, line contamination has potentially significant consequences for the properties of sources detected in flux-limited continuum surveys, biasing the derived redshift distributions and bolometric luminosities. ...

  12. Informing Selection of Nanomaterial Concentrations for ToxCast In Vitro Testing based on Occupational Exposure Potential

    Science.gov (United States)

    Little justification is generally provided for selection of in vitro assay testing concentrations for engineered nanomaterials (ENMs). Selection of concentration levels for hazard evaluation based on real-world exposure scenarios is desirable. We reviewed published ENM concentr...

  13. Darkening of the mid-Himalaya glaciers since 2000 and the potential causes

    International Nuclear Information System (INIS)

    Himalayan glaciers are a vital water source for people in the high regions of Asia. Their complete melting would be a crisis for approximately 1 billion people. Albedo is one of the key parameters that affect the energy balance of the snow and ice surfaces. Since 2000, albedos have been retrieved from satellite data for eleven representative Himalayan glaciers. It was found that most of the glaciers showed declining trends in the albedo of their upper areas, indicating that they have generally become darker in the past decade. A simulation case study in conjunction with in situ measurements showed that light-absorbing constituents (e.g., black carbon and dust) could be partly responsible for this phenomenon during late springtime; the background regional warming could also be responsible. The current surface radiation absorption in Himalayan glaciers could lead to significant melting, causing most of them to be in danger of rapid mass loss. (letter)

  14. Characterization and Metal Detoxification Potential of Moderately Thermophilic Bacillus cereus from Geothermal Springs of Himalaya

    Scientific Electronic Library Online (English)

    Aslam Khan, Ghalib; Muhammad, Yasin; Muhammad, Faisal.

    2014-07-01

    Full Text Available Two thermophilic Bacillus cereus strains (B. cereus-TA2 and B. cereus-TA4) used in the present study were isolated from the geothermal spring of Hunza valley, Gilgit, Pakistan. They showed the ability to withstand and grow at high temperature (85°C). Both these strains could resist multiple metals ( [...] copper, cadmium, mercury, manganese, zinc, arsenic, chromium and selenium). Strain B. cereus-TA4 reduced Cr (VI) at pH 5.0 to 9.0 but maximum reduction (83%) was observed at pH 7.0 after 48 h when initially supplied with 200 µg mL-1 of K2CrO4. Lower initial concentrations such as 100 µg mL-1 supported higher reduction (90 to 95%) than that of high concentration such as 500 µg mL-1 (20 to 30%). Both the strains reduced nearly 70% of Se (IV) after 48 h of growth at pH 7.0 when initially supplied with 200 µg mL-1 of Na2SeO3. The optimum temperature for maximum Se (IV) reduction was 45°C for both the strains.

  15. DNA barcoding of Rhododendron (Ericaceae), the largest Chinese plant genus in biodiversity hotspots of the Himalaya-Hengduan Mountains.

    Science.gov (United States)

    Yan, Li-Jun; Liu, Jie; Möller, Michael; Zhang, Lin; Zhang, Xue-Mei; Li, De-Zhu; Gao, Lian-Ming

    2015-07-01

    The Himalaya-Hengduan Mountains encompass two global biodiversity hotspots with high levels of biodiversity and endemism. This area is one of the diversification centres of the genus Rhododendron, which is recognized as one of the most taxonomically challenging plant taxa due to recent adaptive radiations and rampant hybridization. In this study, four DNA barcodes were evaluated on 531 samples representing 173 species of seven sections of four subgenera in Rhododendron, with a high sampling density from the Himalaya-Hengduan Mountains employing three analytical methods. The varied approaches (nj, pwg and blast) had different species identification powers with blast performing best. With the pwg analysis, the discrimination rates for single barcodes varied from 12.21% to 25.19% with ITS biodiversity for the large genus Rhododendron in the biodiversity hotspots of the Himalaya-Hengduan Mountains. PMID:25469426

  16. Studies of the in vitro anticancer, antimicrobial and antioxidant potentials of selected Yemeni medicinal plants from the island Soqotra

    Directory of Open Access Journals (Sweden)

    Bednarski Patrick J

    2009-03-01

    Full Text Available Abstract Background Recent years have witnessed that there is a revival of interest in drug discovery from medicinal plants for the maintenance of health in all parts of the world. The aim of this work was to investigate 26 plants belonging to 17 families collected from a unique place in Yemen (Soqotra Island for their in vitro anticancer, antimicrobial and antioxidant activities. Methods The 26 plants were extracted with methanol and hot water to yield 52 extracts. Evaluation for in vitro anticancer activity was done against three human cancer cell lines (A-427, 5637 and MCF-7 by using an established microtiter plate assay based on cellular staining with crystal violet. Antimicrobial activity was tested against three Gram-positive bacteria, two Gram-negative bacteria, one yeast species and three multiresistant Staphylococcus strains by using an agar diffusion method and the determination of MIC against three Gram-positive bacteria with the broth micro-dilution assay. Antioxidant activity was investigated by measuring the scavenging activity of the DPPH radical. Moreover, a phytochemical screening of the methanolic extracts was done. Results Notable cancer cell growth inhibition was observed for extracts from Ballochia atro-virgata, Eureiandra balfourii and Hypoestes pubescens, with IC50 values ranging between 0.8 and 8.2 ?g/ml. The methanol extracts of Acanthospermum hispidum, Boswellia dioscorides, Boswellia socotrana, Commiphora ornifolia and Euphorbia socotrana also showed noticeable antiproliferative potency with IC50 values Acacia pennivenia, Boswellia dioscorides, Boswellia socotrana, Commiphora ornifolia, Euclea divinorum, Euphorbia socotrana, Leucas samhaensis, Leucas virgata, Rhus thyrsiflora, and Teucrium sokotranum with inhibition zones > 15 mm and MIC values ? 250 ?g/ml. In addition, the methanolic extracts of Acacia pennivenia, Boswellia dioscorides, Boswellia socotrana and Commiphora ornifolia showed good antioxidant potential at low concentrations (more than 80% at 50 ?g/ml. Conclusion Our results show once again that medicinal plants can be promising sources of natural products with potential anticancer, antimicrobial and antioxidative activity. The results will guide the selection of some plant species for further pharmacological and phytochemical investigations.

  17. Selection of lactic acid bacteria from Brazilian kefir grains for potential use as starter or probiotic cultures.

    Science.gov (United States)

    Zanirati, Débora Ferreira; Abatemarco, Mário; Sandes, Sávio Henrique de Cicco; Nicoli, Jacques Robert; Nunes, Álvaro Cantini; Neumann, Elisabeth

    2015-04-01

    Brazilian kefir is a homemade fermented beverage that is obtained by incubating milk or a brown sugar solution with kefir grains that contribute their different microbiological compositions. It is highly important to isolate and characterize microorganisms from Brazilian kefir grains to obtain starter cultures for the industrial production of a standardized commercial kefir. Thus, the present study aimed to isolate lactic acid bacteria from eight kefir grains that were propagated in milk or sugar solutions from five different locations in Brazil and to select Lactobacillus isolates based on desirable in vitro probiotic properties. One hundred eight isolates from both substrates were identified by amplified ribosomal DNA restriction analysis and/or 16S rRNA gene sequencing and were determined to belong to the following 11 species from the genera: Lactococcus, Leuconostoc, Lactobacillus (L.), and Oenococcus. Leuconostoc mesenteroides, Lactobacillus kefiri, and Lactobacillus kefiranofaciens were isolated only from milk grains, whereas Lactobacillus perolens, Lactobacillus parafarraginis, Lactobacillus diolivorans, and Oenococcus oeni were isolated exclusively from sugar water grains. When the microbial compositions of four kefir grains were evaluated with culture-independent analyses, L. kefiranofaciens was observed to predominant in milk grains, whereas Lactobacillus hilgardii was most abundant in sugar water kefir. Unfortunately, L. hilgardii was not isolated from any grain, although this bacteria was detected with a culture-independent methodology. Fifty-two isolated Lactobacilli were tested for gastric juice and bile salt tolerance, antagonism against pathogens, antimicrobial resistance, and surface hydrophobicity. Three Lactobacillus strains (L. kefiranofaciens 8U, L. diolivorans 1Z, and Lactobacillus casei 17U) could be classified as potential probiotics. In conclusion, several lactic acid bacteria that could be used in combination with yeasts as starter cultures for both milk kefir and sugar water kefir were characterized, and the functional properties of several of the lactobacilli isolated from the kefir grains were suggestive of their possible use as probiotics in both kefir and other dairy products. PMID:25542841

  18. Contrasting response of glacierized catchments in the Central Himalaya and the Central Andes to climate change

    Science.gov (United States)

    Ragettli, Silvan; Pellicciotti, Francesca; Immerzeel, Walter

    2015-04-01

    The Andes of South America and the Himalaya in high-mountain Asia are two regions where advanced simulation models are of vital importance to anticipate the impacts of climate change on water resources. The two mountain systems hold the largest ice masses outside the polar regions. Major rivers originate here and downstream regions are densely populated. In the long run, glacier recession generates concerns about the sustainability of summer runoff. This study benefits from recent efforts of carefully planned short-term field experiments in two headwater catchments in the Central Andes of Chile and in the Central Himalaya in Nepal. The two study catchments contrast in terms of their climate and in the characteristics of their glaciers. A systematic approach is developed, built upon the available local data, to reduce the predictive uncertainty of a state-of-the-art glacio-hydrological model used for the projection of 21st century glacier changes and catchment runoff. The in-situ data are used for model development and step-wise, multivariate parameter calibration. Catchment runoff and remotely sensed MODIS and Landsat snow cover are used for model validation. The glacio-hydrological model simulates the water cycle with a high temporal (hourly time steps) and spatial (100 m grid cells) resolution and accounts for processes typical of both regions like glacier melt under debris cover or mass redistribution through avalanching. Future projections are based on the outputs of twelve stochastically downscaled global climate models for two emission scenarios (RCP 4.5 and RCP 8.5). This is one of the first truly intercomparative modeling studies at the catchment scale across mountain regions of the world to assess and compare future changes in glaciers and snow cover and associated impacts on streamflow production. Both catchments will experience significant glacier mass loss throughout the twenty-first century. However, the trajectories of simulated future runoff and total melt from glaciers differ fundamentally. In the Langtang region in the Central Himalaya, the model results indicate increasing catchment runoff until mid-century and then either slowly declining or constant runoff depending on the climate scenario. In the Juncal region in the Central Andes catchment runoff starts to decline sharply after 2031-2040, so that annual river runoff may decrease by up to 60% until the end of the century. While in the Juncal region the seasonality of runoff may change dramatically, due to less snow- and glacier melt during the summer, the seasonality of runoff in the Central Himalaya will be essentially unaffected by climate change. Differences in catchment response are explained by differences in climate change projections (as precipitation is projected to increase in the Central Himalaya but to decrease in the Central Andes), but also by the differences in glacier characteristics and glacier evolution. Meltwater production of glaciers in Juncal is already on a decline under the present climate. In Langtang, in contrast, the rate of glacier area decrease at lower elevations is exceeded by the rate of additional glacier area at high elevations contributing to melt in a warming climate. As a consequence of this, annual icemelt in the Central Himalaya will reach its peak not before mid-century.

  19. Medieval pulse of great earthquakes in the central Himalaya: Viewing past activities on the frontal thrust

    Science.gov (United States)

    Rajendran, C. P.; John, Biju; Rajendran, Kusala

    2015-03-01

    The Himalaya has experienced three great earthquakes during the last century—1934 Nepal-Bihar, 1950 Upper Assam, and arguably the 1905 Kangra. Focus here is on the central Himalayan segment between the 1905 and the 1934 ruptures, where previous studies have identified a great earthquake between thirteenth and sixteenth centuries. Historical data suggest damaging earthquakes in A.D. 1255, 1344, 1505, 1803, and 1833, although their sources and magnitudes remain debated. We present new evidence for a great earthquake from a trench across the base of a 13 m high scarp near Ramnagar at the Himalayan Frontal Thrust. The section exposed four south verging fault strands and a backthrust offsetting a broad spectrum of lithounits, including colluvial deposits. Age data suggest that the last great earthquake in the central Himalaya most likely occurred between A.D. 1259 and 1433. While evidence for this rupture is unmistakable, the stratigraphic clues imply an earlier event, which can most tentatively be placed between A.D. 1050 and 1250. The postulated existence of this earlier event, however, requires further validation. If the two-earthquake scenario is realistic, then the successive ruptures may have occurred in close intervals and were sourced on adjacent segments that overlapped at the trench site. Rupture(s) identified in the trench closely correlate with two damaging earthquakes of 1255 and 1344 reported from Nepal. The present study suggests that the frontal thrust in central Himalaya may have remained seismically inactive during the last ~700 years. Considering this long elapsed time, a great earthquake may be due in the region.

  20. Recent temperature trends at mountain stations on the southern slope of the central Himalayas

    Indian Academy of Sciences (India)

    Dambaru Ballab Kattel; Tandong Yao

    2013-02-01

    Insufficient long-term in situ observations and complex topographic conditions pose major problems in quantifying the magnitude of climatic trends in mountainous regions such as Nepal. Presented here is three decades (1980–2009) of data on annual maximum, minimum and average temperature trends from 13 mountain stations on the southern slope of the central Himalayas. The stations are located at elevations between 1304 and 2566 m above sea level and with varied topography. Spatial analyses of the average temperature trend show warming in most of the stations. The magnitude of warming is higher for maximum temperatures, while minimum temperatures exhibit larger variability such as positive, negative or no change. These results are consistent with patterns reported in some parts of the Indian subcontinent and Upper Indus Basin, but different from conditions on the Tibetan Plateau (China), where the warming of minimum temperatures is more prominent than that of the maximum temperatures. From the temporal variations, a dramatic increase in temperature is observed in the latest decade, particularly in the average and maximum temperatures. The results from the cumulative sum chart analyses suggest that the thermal regime shifted in 1997. The dramatic enhancement of average temperature in the last decade is strongly consistent with the result of contemporary studies of the surrounding regions, where warming is attributed to an increase in anthropogenic greenhouse gases. However, as in the western Himalayas and the Upper Indus Basin, the mountain stations on the southern slope of the central Himalayas show variability in temperature trends, particularly for the minimum temperature. This inhomogeneous trend is likely ascribed to the differences in topography and microclimatic regime of the observed stations.

  1. Constraints on the tectonic and landscape evolution of the Bhutan Himalaya from thermochronometry

    Science.gov (United States)

    Adams, B. A.; Hodges, K. V.; Whipple, K. X.; Ehlers, T. A.; Soest, M. C.; Wartho, J.

    2015-06-01

    The observed geomorphology and calculated thermal histories of the Bhutan Himalaya provide an excellent platform to test ideas regarding the influence of tectonics and climate on the evolution of a convergent mountain range. However, little consensus has been reached regarding the late Cenozoic history of the Bhutan Himalaya. Some researchers have argued that observed geologic relationships show slowing deformation rates, such that the range is decaying from a geomorphic perspective, while others see the range as growing and steepening. We suggest that a better understanding is possible through the integrated interpretation of geomorphic and thermochronometric data from the comparison of predictions from models of landscape evolution and thermal-kinematic models of orogenic systems. New thermochronometric data throughout Bhutan are most consistent with a significant decrease in erosion rates, from 2 to 3 km/Ma down to 0.1-0.3 km/Ma, around 6-4 Ma. We interpret this pattern as a decrease in rock uplift rates due to the activation of contractional structures of the Shillong Plateau, an uplifted region approximately 100 km south of Bhutan. However, low-relief, fluvial landscapes throughout the Bhutanese hinterland record a late pulse of surface uplift likely due to a recent increase in rock uplift rates. Constraints from our youngest thermochronometers suggest that this increase in rock uplift and surface uplift occurred within the last 1.75 Ma. These results imply that the dynamics of the Bhutan Himalaya and Shillong Plateau have been linked during the late Cenozoic, with structural elements of both regions active in variable ways and times over that interval.

  2. Comparison of EIGEN 6C and EGM 2008 gravity field models via Marussi tensor computed for selected areas of the Earth

    Science.gov (United States)

    Klokocnik, J.; Kostelecky, J.; Sebera, J.; Bezdek, A.

    2012-04-01

    We compare two modern gravity field models, both combined from satellite and terrestrial data. EIGEN 6C comprises already GOCE data while EGM 2008 has only GRACE data. We compare the models via the gravity disturbances and components of the Marussi tensor of the second derivatives of the disturbing potential, namely Tzz. We selected areas where the differences may be interesting or even critical, e.g., in the arctic and antarctic areas (no terrestrial gravity data in Antarctic and only GRACE in EGM 2008). Other studied areas are Himalaya and similar large mountain belts where quality of the terrestrial data may be lower, and further localities, with the impact craters. The resolution of EIGEN 6C is about half of that of EGM 2008, so it is very interesting to watch what details can be achieved for specific areas with EIGEN 6C.

  3. Metabolic responses during initial days of altitude acclimatization in the Eastern Himalayas

    Science.gov (United States)

    Basu, C. K.; Gautam, R. K.; Sharma, R. P.; Kumar, H.; Tomar, O. S.; Sawhney, R. C.; Selvamurthy, W.

    1996-09-01

    The study was carried out on 16 men (aged 20 30 years) to evaluate daily metabolic responses during the early phase of altitude acclimatization at moderate altitudes between 3100 and 4200 m in the Eastern Himalayas. Resting (R) and submaximal exercise (E) oxygen consumption (| VO2) at 100 W at sea level (SL) were 3.25 (SEM 0.15) and 20.31 (SEM 0.77) ml/kg per min respectively. On day 1 at 3110 m both R and E | VO2 decreased ( Pacclimatization to a mid-altitude of 3445 m can be safely avoided where rapid ascent to higher altitude is required.

  4. Hinterland tectonics and drainage evolution recorded by foreland basin archives: the Neogene Siwaliks of the Himalaya

    Science.gov (United States)

    Huyghe, Pascale; van der Beek, Peter; Matthias, Bernet; Catherine, Chauvel; Jean-Louis, Mugnier; Laurent, Husson; François, Chirouze

    2014-05-01

    Provenance analysis and detrital thermochronology of detrital synorogenic sediments, derived from erosion of mountain belts and deposited in surrounding sedimentary basins, are well-established methods to examine the exhumation history of convergent zones, tectonic activity and the associated evolution of the drainage network. We have conducted multidisciplinary studies on magnetostratigraphically dated sections throughout the Neogene Siwalik foreland basin of the Himalayan belt since more than 10 years. Sr, Nd and Hf isotopes are used as provenance indicators, providing information on the nature and size of catchment basins and their evolution through time in response to tectonics. Detrital zircon and apatite thermochronology provides constraints on exhumation rates in the hinterland of the Himalaya and the deformation of the Sub-Himalayan foreland basin. Throughout the Himalaya, detrital zircons from the Siwaliks generally show three age peaks: two static peaks (i.e., displaying constant peak ages through time), and a moving peak. The latter shows a constant lag time of ~4 m.y. corresponding to source-area exhumation rates on the order of 1.8 km/my, while the two static peaks respectively reveal a major 15-20 Ma exhumation event in the belt, the significance of which is still debated, and inheritance of pre-Himalayan ages that indicate recycling of Tethyan sediments. Therefore, our ZFT results suggest that the exhumation dynamics are broadly similar throughout the Himalaya since at least 13 m.y, as also shown by the Bengal Fan detrital sediment record. We relate this switch in tectonic regime to the destabilization of the Himalayan wedge that is rendered overcritical as a response to the transience of dynamic topography caused by the deforming underlying Indian slab. Nonetheless, in detail, the timing of thrusting in the Siwalik domain is delayed by about 1 my eastward as demonstrated by both structural and apatite fission-track data, suggesting overall eastward propagation of the main faults. The evolution of the sedimentary provenance can be explained by overall forward propagation of deformation in the Himalayan fold-thrust belt. In both the eastern and western syntaxes, it also shows stability of the major drainage systems of the Yarlung-Brahmaputra and Indus, respectively, suggesting that hinterland river incision kept pace with uplift of the syntaxes during the Neogene. Drainage reorganization may take place in the foreland basin because of thin-skinned tectonics but did not significantly affect sediment routing and the contribution of different sources of the upper catchment to the overall sediment budget. In contrast, major rivers in the Central Himalaya (such as the Kali Gandaki or the Karnali) could have been affected by changes in their upper catchment.

  5. Joint spatial variability of aerosol, clouds and rainfall in the Himalayas from satellite data

    Directory of Open Access Journals (Sweden)

    P. Shrestha

    2010-09-01

    Full Text Available Satellite-based precipitation, Aerosol Optical Depth (AOD, Cloud Optical Depth (COD, and Aerosol Index (AI data were used to characterize the linkages among landform and the intra-annual variability of aerosols, cloudiness and rainfall in the Himalayas using empirical orthogonal function (EOF analysis. The first modes of AOD and AI show the presence of two branches of dust aerosol: over the Indus river basin and the Thar desert with a sharp west-east gradient parallel to the southern slopes of the Himalayas – the Southern Branch; and the second against the slopes of the Tian Shan and over the Takla Makan desert in the Tibetan Plateau-the Northern branch. The third EOF mode of AOD accounts for about 7% of overall variance of AOD. It is attached to the foothills of the Himalayas east of the Aravalli range peaking in April-May-June followed by a sharp decrease in July during the first active phase of the monsoon. The first and second EOF modes of COD and precipitation show consistent patterns against the central and eastern Himalayas and along the ocean-land boundaries in western India and the Bay of Bengal. The break in cloudiness and rainfall between the winter and the monsoon seasons is captured well by the second EOF mode of COD and rainfall concurrent with the aerosol build up mode (April–May over the region depicted by the third mode of AOD. The results show that the Aravalli range separates the two different modes of aerosol variability over northern India with dust aerosols to the west and polluted mixed aerosols to the east consistent with its role in regional circulation and precipitations patterns as per Barros et al. (2004 and Chiao and Barros (2007. SVD analysis between rainfall, COD and AOD showed a pattern of aerosol loading (resembling EOF3 of MODIS AOD extending from 80° E~90° E that peaks during the winter and pre-monsoon seasons and decays abruptly during the monsoon: the regions of aerosol buildup during the pre-monsoon season and the areas of high rainfall/cloudiness during the monsoon are collocated and have opposite signs suggesting aerosol-cloud-rainfall interaction. It is proposed that the third EOF of AOD maps the area where aerosol-cloud-rainfall interactions play an important role in the regional hydro-climatology.

  6. Village Level Disaster Risk Management through Participatory Learning and Action (PLA) at Uttarakhand Himalaya, India

    OpenAIRE

    Abhinav Walia and Indrajit Pal

    2013-01-01

    Participatory Leaning and Action (PLA) approach was exercised in the village Jardhar situated on the foot hills of Himalaya above 1550 meters above the sea level, lying between Latitude 30° 32:25’ -30 ° 34.08′N and Longitude 78°34.’-78°36′E. The total population of this village is around 1484. Rationale behind this study is to empower the rural communities and to follow the bottom up approach for the development of a village level disaster management plan. As w...

  7. Crustal melt granites and migmatites along the Himalaya: melt source, segregation, transport and granite emplacement mechanisms

    OpenAIRE

    Searle, MP; Cottle, JM; Streule, MJ; Waters, DJ

    2010-01-01

    India-Asia collision resulted in crustal thickening and shortening, metamorphism and partial melting along the 2200 km-long Himalayan range. In the core of the Greater Himalaya, widespread in situ partial melting in sillimanite+K-feldspar gneisses resulted in formation of migmatites and Ms+Bt+Grt+Tur±Crd±Sil leucogranites, mainly by muscovite dehydration melting. Melting occurred at shallow depths (4-6 kbar; 15-20 km depth) in the middle crust, but not in the lower crust. 87Sr/ 86Sr ratios of...

  8. FAIR FESTIVAL AND THERE RELIGIOUS BELIEF IN HIMACHAL HIMALAYA - A STUDY OF BUDI DIWALI OF NIRMAND

    OpenAIRE

    Hiramani Kashyap

    2014-01-01

    Himachal Pradesh is also known as the land of god and goddess. It is situated in lap of western Himalaya and full of natural and cultural beauty. Budi Diwali fair is held on Maghar Amawasya for three days in Village Nirmand of Kullu district. It is associated with the battle of Mahabharta which is said to have started on that day. It is also associated to commemorate the killing of two demons Dano and Asur, who resided at Nirmand in the form of snake. It starts with a brief re...

  9. Origin and radiative forcing of black carbon transported to the Himalayas and Tibetan Plateau

    OpenAIRE

    Kopacz, M.; Mauzerall, D. L.; J. Wang(Institute of High Energy Physics, Chinese Academy of Sciences, Beijing); Leibensperger, E.M.; Henze, D.K; Singh, K.

    2010-01-01

    The remote and high elevation regions of central Asia are influenced by black carbon (BC) emissions from a variety of locations. BC deposition contributes to melting of glaciers and questions exist, of both scientific and policy interest, as to the origin of the BC reaching the glaciers. We use the adjoint of the GEOS-Chem model to identify the location from which BC arriving at a variety of locations in the Himalayas and Tibetan Plateau originates. We then calculate its direct and snow-albed...

  10. Medicinal flora and ethnoecological knowledge in the Naran Valley, Western Himalaya, Pakistan

    Directory of Open Access Journals (Sweden)

    Khan Shujaul M

    2013-01-01

    Full Text Available Abstract Background Mountain ecosystems all over the world support a high biological diversity and provide home and services to some 12% of the global human population, who use their traditional ecological knowledge to utilise local natural resources. The Himalayas are the world's youngest, highest and largest mountain range and support a high plant biodiversity. In this remote mountainous region of the Himalaya, people depend upon local plant resources to supply a range of goods and services, including grazing for livestock and medicinal supplies for themselves. Due to their remote location, harsh climate, rough terrain and topography, many areas within this region still remain poorly known for its floristic diversity, plant species distribution and vegetation ecosystem service. Methods The Naran valley in the north-western Pakistan is among such valleys and occupies a distinctive geographical location on the edge of the Western Himalaya range, close to the Hindu Kush range to the west and the Karakorum Mountains to the north. It is also located on climatic and geological divides, which further add to its botanical interest. In the present project 120 informants were interviewed at 12 main localities along the 60 km long valley. This paper focuses on assessment of medicinal plant species valued by local communities using their traditional knowledge. Results Results revealed that 101 species belonging to 52 families (51.5% of the total plants were used for 97 prominent therapeutic purposes. The largest number of ailments cured with medicinal plants were associated with the digestive system (32.76% responses followed by those associated with the respiratory and urinary systems (13.72% and 9.13% respectively. The ailments associated with the blood circulatory and reproductive systems and the skin were 7.37%, 7.04% and 7.03%, respectively. The results also indicate that whole plants were used in 54% of recipes followed by rhizomes (21%, fruits (9.5% and roots (5.5%. Conclusion Our findings demonstrate the range of ecosystem services that are provided by the vegetation and assess how utilisation of plants will impact on future resource sustainability. The study not only contributes to an improved understanding of traditional ethno-ecological knowledge amongst the peoples of the Western Himalaya but also identifies priorities at species and habitat level for local and regional plant conservation strategies.

  11. Impact of Different Land Use Management on Soil Enzyme Activities and Bacterial Genetic Fingerprints of North-Western Himalayas

    Directory of Open Access Journals (Sweden)

    Raj Deo Singh

    2014-12-01

    Full Text Available Land uses has significant impact on soil biological properties that incessantly intimates the soil quality change and are assessed by soil microbial and biochemical indicators, as they are highly sensitive to change in environment. The purpose of this study was to investigate the impact of land use on soil enzyme activities and gene diversity in selected location of Northwestern Himalayas, India. Nine different land use system of similar soil type at depth 0-15 cm were analyzed for soil enzymes (Dehydrogenase, Acid Phosphatase, Alkaline Phosphatase, Nitrate Reductase, Arylsulphatase, and Phytase and genetic fingerprints (Randomly Amplified Polymorphic DNA analysis. The land use systems investigated are Oak (Quercus incana, Deodar (Cedrus deodara, Pine (Pinus roxburghii trees, Apple orchids and crop based systems in uplands and valleys. All the soil enzymes were significantly higher in forest ecosystem followed by organic farm and conventional maize-wheat farm soil. The principal component analysis (PCA of nine different land use systems based on soil enzymes shows significant variation in data and all the long-term agricultural lands were segregated together. However maize-wheat and organic farm are group together in the PCA plot. Hierarchical clustering by wards method of soil enzymes clusters the deodar forest soil, oak forest soil and organic farming in one cluster and segregates remaining land use system in another. RAPD analysis showed high polymorphism between samples and similarity indexing using unweighted pair-group method with arithmetic averages resulted in four clusters. Land use showed significantly negative impact on soil enzymes and genetic fingerprints in long-term agricultural lands as compared to natural forest ecosystem and organic farming as reveal by RAPD assisted marker.

  12. Selectivity in the potentiation of antibacterial activity of ?-peptide/?-peptoid peptidomimetics and antimicrobial peptides by human blood plasma

    DEFF Research Database (Denmark)

    Hein-Kristensen, Line; Knapp, Kolja M.; Franzyk, Henrik; Gram, Lone

    2013-01-01

    activity. Plasma potentiation was not mediated by an LL-37 analogue, lysozyme or hydrogen peroxide; however, plasma potentiation of activity was abolished when the complement system was heat-inactivated. Time-course experiments indicated that potentiation was due to plasma-mediated effects on bacterial...

  13. Event-Related Potentials (ERPs) in Second Language Research: A Brief Introduction to the Technique, a Selected Review, and an Invitation to Reconsider Critical Periods in L2

    Science.gov (United States)

    Steinhauer, Karsten

    2014-01-01

    This article provides a selective overview of recent event-related brain potential (ERP) studies in L2 morpho-syntax, demonstrating that the ERP evidence supporting the critical period hypothesis (CPH) may be less compelling than previously thought. The article starts with a general introduction to ERP methodology and language-related ERP profiles…

  14. Potential Signals of Natural Selection in the Top Risk Loci for Coronary Artery Disease: 9p21 and 10q11

    Science.gov (United States)

    Zanetti, Daniela; Carreras-Torres, Robert; Esteban, Esther

    2015-01-01

    Background Coronary artery disease (CAD) is a complex disease and the leading cause of death in the world. Populations of different ancestry do not always share the same risk markers. Natural selective processes may be the cause of some of the population differences detected for specific risk mutations. Objective In this study, 384 single nucleotide polymorphisms (SNPs) located in four genomic regions associated with CAD (1p13, 1q41, 9p21 and 10q11) are analysed in a set of 19 populations from Europe, Middle East and North Africa and also in Asian and African samples from the 1000 Genomes Project. The aim of this survey is to explore for the first time whether the genetic variability in these genomic regions is better explained by demography or by natural selection. Results The results indicate significant differences in the structure of genetic variation and in the LD patterns among populations that probably explain the population disparities found in markers of susceptibility to CAD. Conclusions The results are consistent with potential signature of positive selection in the 9p21 region and of balancing selection in the 9p21 and 10q11. Specifically, in Europe three CAD risk markers in the 9p21 region (rs9632884, rs1537371 and rs1333042) show consistent signals of positive selection. The results of this study are consistent with a potential selective role of CAD in the configuration of genetic diversity in current human populations. PMID:26252781

  15. The Discovery of Potentially Selective Human Neuronal Nitric Oxide Synthase (nNOS Inhibitors: A Combination of Pharmacophore Modelling, CoMFA, Virtual Screening and Molecular Docking Studies

    Directory of Open Access Journals (Sweden)

    Guanhong Xu

    2014-05-01

    Full Text Available Neuronal nitric oxide synthase (nNOS plays an important role in neurotransmission and smooth muscle relaxation. Selective inhibition of nNOS over its other isozymes is highly desirable for the treatment of neurodegenerative diseases to avoid undesirable effects. In this study, we present a workflow for the identification and prioritization of compounds as potentially selective human nNOS inhibitors. Three-dimensional pharmacophore models were constructed based on a set of known nNOS inhibitors. The pharmacophore models were evaluated by Pareto surface and CoMFA (Comparative Molecular Field Analysis analyses. The best pharmacophore model, which included 7 pharmacophore features, was used as a search query in the SPECS database (SPECS®, Delft, The Netherlands. The hit compounds were further filtered by scoring and docking. Ten hits were identified as potential selective nNOS inhibitors.

  16. Selected constants oxydo-reduction potentials tables of constants and numerical data affiliated to the International Union of Pure and Applied Chemistry, v.8

    CERN Document Server

    Charlot, G

    2013-01-01

    Selected Constants: Oxydo-Reduction Potentials contains Tables of the most probable value of the normal oxidation-reduction potential, or of the formal or apparent potential, of a given oxidation-reduction system. This book is prepared under the sponsorship of the Commission on Electrochemical Data of the Section of Analytical Chemistry of the International Union of Pure and Applied Chemistry. It is included in a general program of the Section of Analytical Chemistry. Entry items are classified in alphabetical order. This book will be of value to specialized and non-specialized chemists, teach

  17. Chemical composition and biological effects of Artemisia maritima and Artemisia nilagirica essential oils from wild plant of Western Himalaya

    Science.gov (United States)

    Artemisia species possess pharmacological properties that are used for medical purposes worldwide. In this paper, the essential oils from the aerial parts of A. nilagirica and A. maritima from the western Indian Himalaya region are described. The main compounds analyzed by simultaneous GC/MS and GC/...

  18. Reorientation of lineation in the Central Crystalline Zone, Munsiari–Milam area of the Kumaun Greater Himalaya

    Indian Academy of Sciences (India)

    A K Verma; A R Bhattacharya

    2015-03-01

    During large scale ductile shear deformation, linear features of the rocks tend to be reoriented towards the direction of bulk shear. This is demonstrated in a crustal scale shear zone of the Himalaya, the Main Central Thrust (MCT), typically exposed in the Munsiari–Milam area of eastern Kumaun Greater Himalaya. Along the MCT, the crystalline rocks of the Greater Himalaya are thrust over the younger sedimentary belt of the Lesser Himalaya. In the study area, the scatter of lineation orientation in the vicinity of the MCT has been observed to drastically reduce within 27° in a zone of about 18 km (about 13 km in the crystalline rocks and about 5 km in the sedimentary rocks). Beyond this zone, the scatter is very high, up to 70° or more. The low scatter of lineation orientation around the MCT could be related to the strong ductile shear deformation associated with the movement along this thrust due to which the linear features got reoriented towards the direction of bulk shear. Away from this zone, ductile shearing had negligible or no effect on the rocks and, therefore, the scatter of lineation remains very high.

  19. Identification and conservation of important plant areas (IPAS) for the distribution of medicinal, aromatic and economic plants in the Hindukush-Himalaya mountain range

    International Nuclear Information System (INIS)

    Study on the identification of Important Plant Areas (IPAs) was conducted in seven valleys of Hindukush-Himalayas mountainous ranges of Pakistan during 2005 and 2006. The principal aim of the study is to search new avenues for the conservation and sustainable utilization of threatened medicinal and economic plants and their habitats in IPAs. IPAs are sites of tremendous ecological and economic values that still exist in the world and are being managed on specific sites to study wild plant diversity. Several of such plants are used in the traditional medicines that are being used since the dawn of history to provide basic healthcare to people the world over. According to WHO, 80% of the human population of Africa still use medicinal plants in their primary healthcare. The popularity of herbal drugs is on the constant rise in many developed countries of the world, while in developing countries like Pakistan; medicinal plants contribute significantly to the income sources of people living in remote areas. Keeping such importance in view, the World Health Organization (WHO) launched a global vision in the form of 'Global Strategy for Plant Conservation' having various targets and mile stones. Target 5 of the strategy required for the global integration of the herbal medicine in health care system with proper identification of medicinal plants and the conservation of sites where such plants are found naturally, as its basic elements. In order to contribute to the specified target, WHO advised the relevant institutions to develop research plans and conservation programmes that are focused on the Global strategy in general and target 5 in specific. While complementing the appeal and contributing to its vision, a study was conducted in various eco-systems of the Pakistan's Hindukush-Himalayas region, identifying Important Plant Areas (IPAs) for their subsequent conservation and uses for scientific purposes. Site selection for the study was based on: 1). Exceptional vegetation richness for the representative bio-geographic zone; 2). Presence of naturally occurring medicinal herbs with species of global or regional concern, and (3). Threatened habitats that are supporting plant species of medicinal and economic values. Apart from various values of the selected sites such as their scientific and economic importance, the selected sites had a treasure of indigenous knowledge related to the wise uses and conservation of medicinal plants. The study also focused on exploring the complex natural interactions between plants and other organisms; their dependence under various environmental parameters; traditional knowledge of the local inhabitants; and the significance of the landscape to Conserve such plants on long-term basis. (author)

  20. Phenotypic differentiation of Barilius bendelisis (Cypriniformes: Cyprinidae in four rivers from Central Indian Himalaya

    Directory of Open Access Journals (Sweden)

    Javaid Iqbal Mir

    2015-03-01

    Full Text Available Barilius bendelisis, commonly known as Indian Hill Trout is an upland water fish of South East Asia. It belongs to the family Cyprinidae and dwells in shallow, clear and cold water. In this study, the intraspecific variation of Barilius bendelisis, on the basis of morphometric characters, was investigated. Altogether, 402 specimens were collected from four rivers in the Central Indian Himalaya. A truss network was constructed by interconnecting 12 landmarks to yield 30 distance variables that were extracted from digital images of specimens using tpsDig2 and PAST software. Allometric transformed truss measurements were subjected to univariate analysis of variance, factor analysis and discriminant analysis. All variables exhibited significant differences between the populations. Altogether 88% of the specimens were classified into their original populations (81.98% under a ‘leave-one-out’ procedure. With factor analysis measurements of the head region, the middle portion and the caudal region had high loadings on the first and second axis. The results indicated that B. bendelisis has significant phenotypic heterogeneity between the geographically isolated regions of Central Indian Himalaya. We hypothesize that the marked interspecific variation in B. bendelisis is the result of local ecological conditions.

  1. Diet of Threatened Pheasant Species in Himalayas, India – A Faecal Analysis Approach

    Directory of Open Access Journals (Sweden)

    Mohammad Shah Hussain

    2013-06-01

    Full Text Available The aim of this paper is to determine diet composition of threatened pheasant species i.e. Satyr Tragopan Tragopan satyra, Himalayan Monal Lophophorus impejanus, Kaleej Lophura leucomelana and Koklass Pucrasia macrolopha in their native forest which was never studied earlier. A study was conducted in the Kumaon region of western Himalaya for two years by collecting dropping material. Faeces were identified through direct sighting of defecating species. The diet items of each pheasant species mainly comprised plant materials followed by invertebrates and grit. A significant difference was observed in consuming food items by all pheasant species. Monal emerged as a specialist feeder on plants which were not eaten by other species. The Satyr and Koklass were more similar in terms of diet composition in both seasons while Kaleej and Monal were least similar, only invertebrates and grit were common in the diet of these species. No significant difference was observed in diet composition in different seasons of all pheasant species. The results expected to provide valuable information for the management of these pheasants in Himalayas.

  2. Elemental and individual particle analysis of atmospheric aerosols from high Himalayas.

    Science.gov (United States)

    Cong, Zhiyuan; Kang, Shichang; Dong, Shuping; Liu, Xiande; Qin, Dahe

    2010-01-01

    Atmospheric aerosols were collected during the scientific expedition to Mt. Qomolangma (Everest) in May-June, 2005. The elemental concentrations of the aerosols were determined by inductively coupled plasma mass spectrometry. This yielded data for the concentration of 14 elements: Na, Mg, Al, K, Ca, Ti, V, Cr, Mn, Fe, Ni, Cu, Zn, and Pb. The mean elemental concentrations were generally comparable with those from central Asia and the Arctic, while much higher than those from Antarctic. Size, morphology, and chemical composition of 900 individual aerosol particles were determined by scanning electron microscopy and energy-dispersive X-ray microanalysis. Based on morphology and elemental composition, the particles were clustered into eight groups: soot (8%), tar ball (3%), alumosilicates/silica (55%), calcium sulfate (16%), Ca/Mg carbonate (2%), Fe/Ti-rich particles (3%), Pb-rich particles (1%), and biological particles (12%). The sampling site, located at 6,520 m in the Himalayas, is particularly remote and located at high altitude. Nonetheless, high aerosol enrichment factors for copper, chromium, lead, nickel, vanadium, and zinc all suggest the influence of long-range transported pollution, while enrichment in calcium and the presence of alumino-silicates in individual particle analyses indicates a distinct mineral dust influence. The backward air mass trajectories showed that the northwestern part of India may contribute to the atmospheric aerosol in the central high Himalayas. PMID:19083111

  3. The melting Himalayas: cascading effects of climate change on water, biodiversity, and livelihoods.

    Science.gov (United States)

    Xu, Jianchu; Grumbine, R Edward; Shrestha, Arun; Eriksson, Mats; Yang, Xuefei; Wang, Yun; Wilkes, Andreas

    2009-06-01

    The Greater Himalayas hold the largest mass of ice outside polar regions and are the source of the 10 largest rivers in Asia. Rapid reduction in the volume of Himalayan glaciers due to climate change is occurring. The cascading effects of rising temperatures and loss of ice and snow in the region are affecting, for example, water availability (amounts, seasonality), biodiversity (endemic species, predator-prey relations), ecosystem boundary shifts (tree-line movements, high-elevation ecosystem changes), and global feedbacks (monsoonal shifts, loss of soil carbon). Climate change will also have environmental and social impacts that will likely increase uncertainty in water supplies and agricultural production for human populations across Asia. A common understanding of climate change needs to be developed through regional and local-scale research so that mitigation and adaptation strategies can be identified and implemented. The challenges brought about by climate change in the Greater Himalayas can only be addressed through increased regional collaboration in scientific research and policy making. PMID:22748090

  4. Recent atmospheric dust deposition in an ombrotrophic peat bog from the Himalaya

    International Nuclear Information System (INIS)

    Ombrotrophic peat bogs, are important natural archives for records of atmospheric pollution by heavy metals. As continental geochemical archives in exclusively recording past atmospheric deposition, they have the unique advantage of a wide global distribution relative to ice cores. Mean annual depositional fluxes of these elements across the peat bog surface are mainly controlled by the atmospheric concentration and total rainfall. To characterize historical trends in the extent and sources of environmental pollution, a peat core from the Pinder Valley (30.05°N, 79.93°E) in the Himalaya was collected. 210Pb and 137Cs radionuclides, with well-define fallout records are used for dating the past 150 years of peat accumulation. Beyond this, 14C AMS dating was used for dating the core. The activities of radionuclides were measured using High Purity Germanium Gamma detector and the concentrations of refractory lithogenic (AI, Ca, Fe, Mn, V and Ti) and trace elements (Pb, Cu, Zn, Co, Ni, Mo, Cr, Sr and Ba) using ICP-MS. In this study, the historical records obtained from the peat bog from the Himalaya extending up to 5000 years show evidence for rising anthropogenic inputs of trace metals to the remote high altitude atmosphere since 1970s, resulting largely from fossil fuel consumption, non-ferrous metal production, coal-powered electricity generation and fertilizer use. Geochemistry of peat and the analysis of past environmental changes will be presented. (author)

  5. A CERN flag is set to wave up in the Himalayas

    CERN Multimedia

    Roberto Cantoni

    2010-01-01

    On 18 October, Hubert Reymond, from the Industrial Controls and Engineering group of the EN Department, will be leaving to Nepal with a CERN flag in his backpack. He will place it at the highest point of his trek across the Annapurna mountains in the Himalayas, Thorong La pass, at 5,416 m above sea level.   A view of the Annapurna mountains (source: www.flickr.com/minutesalone) “Is there any official CERN flag I can carry with me during my trek through Nepal?” Some days ago, the Press Office was confronted with this unusual (but see box) question from Hubert Reymond. From 18 October to 10 November, Reymond, who works as an industrial computing engineer in the EN Department, will be trekking across the 55 km-long Annapurna massif in the Himalayas, whose highest point lies at 8,091 m (making it the 10th-highest summit in the world). The area is well-known to trekkers from around the world, as it includes several world-class circuits, including the Annapurna circuit which Reym...

  6. Radon and thoron monitoring in the environment of Kumaun Himalayas: survey and outcomes

    Energy Technology Data Exchange (ETDEWEB)

    Ramola, R.C. E-mail: rcramola@sancharnet.in; Negi, M.S.; Choubey, V.M

    2005-07-01

    Monitoring of radon, thoron and their daughter products was carried out in houses of Kumaun Himalaya, India using LR-115 plastic track detectors. The measurements were made in residential houses from June 1999 to May 2000 at a height of 2.5 m from ground level using a twin chamber radon dosimeter. The twin chamber radon dosimeter can record the values of radon, thoron and their decay products separately. Maximum and minimum indoor radon and thoron concentrations were evaluated and activity concentrations of radon and thoron daughters were estimated. The resulting dose rates due to radon, thoron and their decay products varied from 0.04 to 1.89 {mu}Sv/h. A detailed analysis of the distribution of radon, thoron and their decay products inside the house is also reported. The observed dose rates inside the houses of Kumaun Himalaya were found to be lower than the ICRP recommended value of 200 Bq/m{sup 3} and thus are within safe limits.

  7. Radon and thoron monitoring in the environment of Kumaun Himalayas: survey and outcomes.

    Science.gov (United States)

    Ramola, R C; Negi, M S; Choubey, V M

    2005-01-01

    Monitoring of radon, thoron and their daughter products was carried out in houses of Kumaun Himalaya, India using LR-115 plastic track detectors. The measurements were made in residential houses from June 1999 to May 2000 at a height of 2.5 m from ground level using a twin chamber radon dosimeter. The twin chamber radon dosimeter can record the values of radon, thoron and their decay products separately. Maximum and minimum indoor radon and thoron concentrations were evaluated and activity concentrations of radon and thoron daughters were estimated. The resulting dose rates due to radon, thoron and their decay products varied from 0.04 to 1.89 microSv/h. A detailed analysis of the distribution of radon, thoron and their decay products inside the house is also reported. The observed dose rates inside the houses of Kumaun Himalaya were found to be lower than the ICRP recommended value of 200 Bq/m3 and thus are within safe limits. PMID:15571877

  8. Kashmir Basin Fault and its tectonic significance in NW Himalaya, Jammu and Kashmir, India

    Science.gov (United States)

    Shah, A. A.

    2015-10-01

    The Kashmir Basin Fault is located in the Jammu and Kashmir region of Kashmir Basin in NW Himalaya, India. It is a classic example of an out-of-sequence thrust faulting and is tectonically active as observed from multiple geological evidences. Its geomorphology, structure and lateral extent indicate significant accommodation of stress since long, which is further supported by the absence of a large earthquake in this region. It seems this fault is actively accommodating some portion of the total India-Eurasia convergence, apart from two well-recognised active structures the Medlicott-Wadia Thrust and the Main Frontal Thrust, which are referred in Vassallo et al. (Earth Planet Sci Lett 411:241-252, 2015). This requires its quantification and inclusion into slip distribution scheme of NW Himalaya. Therefore, it should be explored extensively because this internal out-of-sequence thrust could serve major seismic hazard in KB, repeating a situation similar to Muzaffarabad earthquake of Northern Pakistan in 2005.

  9. Seismic properties of naturally deformed quartzites of the Alaknanda valley, Garhwal Himalaya, India

    Indian Academy of Sciences (India)

    Ruchika Sharma Tandon; Vikram Gupta; Koushik Sen

    2015-08-01

    The present contribution summarizes the results of a study focusing on the influence of quartz microstructures on the seismic wave velocities in the quartzites of the Garhwal Himalaya. Quartzites being monomineralic were chosen for the present study so as to nullify the effect of other mineral constituents on the seismic velocity. Samples were collected from different tectonic settings of the Higher and Lesser Himalayas which are separated from one another by the major tectonic zone ‘Main Central Thrust’ (MCT). These are mainly Pandukeshwar quartzite, Tapovan quartzite and Berinag quartzite. The samples of Berinag quartzite were collected from near the klippen and the thrust, termed as Alaknanda Thrust. The vast differences in microstructures and associated seismic wave velocities have been noted in different quartzites. It has also been observed that quartzites of the MCT zone and Alaknanda Thrust have higher seismic velocities. This is because of their coarse-grained nature of the rocks as evidenced by the strong positive relation between seismic velocities and grain area. The coarsening is either due to the operation of grain boundary migration and grain area reduction process or high aspect ratio/shape preferred orientation. The quartzites located around Nandprayag Klippen have undergone static recrystallization and exhibit the lowest seismic wave velocities.

  10. Southern limits of major earthquake ruptures along the Himalaya between longitudes 75° and 90°E

    Science.gov (United States)

    Chander, Ramesh

    1989-12-01

    The ruptures responsible for major earthquakes along the Himalayan Convergent Plate Margin (HCPM) occur in a strikewise oriented zone of frictional failure and relative slip in a buried detachment along the upper surface of the Indian Shield rocks subducting under the Himalaya. The southern limit of the rupture zone is a geotectonic lineament whose geographic location is important in assessing risk due to earthquakes. A major part of this article is taken up in arguing that the available macroseismic and instrumental evidence for the 1934 Bihar-Nepal earthquake is consistent with the view that the rupture which caused it occurred in the detachment mostly under the Lesser Himalaya northward from the vicinity of the surface trace of the Main Boundary Thrust (MBT). Since a similar location has been inferred by others for the 1905 Kangra earthquake rupture, a basis arises for postulating that, over more than half of the length of the HCPM between 75% and 90° E longitudes, the ruptures responsible for major earthquakes lie in the detachment with their southern limits geographically similarly close to the surface trace of the MBT. This includes the nearly 700 km long seismic gap between the 1905 and 1934 ruptures.

  11. Glacier surface velocity estimation using SAR interferometry technique applying ascending and descending passes in Himalayas

    Science.gov (United States)

    Kumar, V.; Venkataramana, G.; Høgda, K. A.

    2011-08-01

    In this study ascending and descending passes interferometric synthetic aperture radar (InSAR) techniques are used for glacier surface velocity estimation in the Himalaya. Single-track interferometric measurements are sensitive to only a single component of the three dimensional (3-D) velocity vectors. European Remote Sensing satellites (ERS-1/2) tandem mission data in ascending and descending tracks provide an opportunity to resolve the three velocity components under the assumption that glacier flow is parallel to its surface. Using the surface slope as an essential input in this technique the velocity pattern of Siachen glacier in Himalaya has been modelled. Glaciers in the Himalayan region maintain excellent coherence of SAR return signals in one-day temporal difference. As a result we could obtain spatially continuous surface velocity field with a precision of fraction of radar wavelength. The results covering the main course of glacier are analysed in terms of spatial and temporal variations. A maximum velocity of 43 cm/day has been observed in the upper middle portion of the glacier. This technique has been found accurate for monitoring the flow rates in this region, suggesting that routine monitoring of diurnal movement Himalayan glaciers would be immensely useful in the present day context of climate change.

  12. Use of objective analysis to estimate winter temperature and precipitation at different stations over western Himalaya

    Indian Academy of Sciences (India)

    Jagdish Chandra Joshi; Ashwagosha Ganju

    2010-10-01

    Temperature and fresh snow are essential inputs in an avalanche forecasting model.Without these parameters,prediction of avalanche occurrence for a region would be very difficult.In the complex terrain of Himalaya,nonavailability of snow and meteorological data of the remote locations during snow storms in the winter is a common occurrence.In view of this persistent problem present study estimates maximum temperature,minimum temperature,ambient temperature and precipitation intensity on different regions of Indian western Himalaya by using similar parameters of the neighbouring regions.The location at which parameters are required and its neighbouring locations should all fall in the same snow climatic zone.Initial step to estimate the parameters at a location,is to shift the parameters of neighbouring regions at a reference height corresponding to the altitude of the location at which parameters are to be estimated.The parameters at this reference height are then spatially interpolated by using Barnes objective analysis.The parameters estimated on different locations are compared with the observed one and the Root Mean Square Errors (RMSE)of the observed and estimated values of the parameters are discussed for the winters of 2007 –2008.

  13. Observed linear trend in few surface weather elements over the Northwest Himalayas (NWH) during winter season

    Indian Academy of Sciences (India)

    Dan Singh; Vikas Sharma; Vikas Juyal

    2015-04-01

    Linear trends in few surface weather variables such as air temperatures (maximum temperature, minimum temperature), snow and rainy days, snowfall and rainfall amounts, rainfall contribution to seasonal total precipitation amount, seasonal snow cover depth and snow cover days (duration) are examined from winter-time observations at 11 stations located over the Northwest Himalayas (NWH). This study indicates that snowfall tends to show a decline in this region, while the rainfall tends to increase during the winter months. Seasonal snow cover depth and seasonal snow cover days also tend to show a decline over the NWH. Decrease in seasonal snow cover depth and duration have reduced the winter period in terms of availability of seasonal snow cover over the NWH during the last 2–3 decades. Other surface weather variables also exhibited significant temporal changes in recent decades. Observed trends in temperature and precipitation over the NWH in recent decades are also supported by long data series of temperature over the western Himalayas (WH), north mountain India (NMI) rainfall data and reanalysis products.

  14. Wintertime land surface characteristics in climatic simulations over the western Himalayas

    Indian Academy of Sciences (India)

    A P Dimri

    2012-04-01

    Wintertime regional climate studies over the western Himalayas with ICTP-RegCM3 simulations through 22 years has shown systematic biases in precipitation and temperature fields. The model simulated precipitation shows systematically wet bias. In surface temperature simulations, positive and negative biases of 2°–4°C occurred. Experiment without (CONT) and with subBATS (SUB) shows that later scheme performs better, especially for precipitation. Apart from the role of topography and model internal variability, land surface characteristics also have profound impact on these climatic variables. Therefore, in the present study, impacts of land surface characteristics are investigated through cool/wet and warm/dry winter climate by CONT and SUB simulations to assess systematic biases. Since SUB experiment uses detailed land-use classification, systematic positive biases in temperature over higher elevation peaks are markedly reduced. The change has shown reduced excessive precipitation as well. Most of the surface characteristics show that major interplay between topography and western disturbances (WDs) takes place along the foothills rather than over the higher peaks of the western Himalayas.

  15. Longest time series of glacier mass changes in the Himalaya based on stereo imagery

    Directory of Open Access Journals (Sweden)

    T. Bolch

    2010-12-01

    Full Text Available Mass loss of Himalayan glaciers has wide-ranging consequences such as declining water resources, sea level rise and an increasing risk of glacial lake outburst floods (GLOFs. The assessment of the regional and global impact of glacier changes in the Himalaya is, however, hampered by a lack of mass balance data for most of the range. Multi-temporal digital terrain models (DTMs allow glacier mass balance to be calculated since the availability of stereo imagery. Here we present the longest time series of mass changes in the Himalaya and show the high value of early stereo spy imagery such as Corona (years 1962 and 1970 aerial images and recent high resolution satellite data (Cartosat-1 to calculate a time series of glacier changes south of Mt. Everest, Nepal. We reveal that the glaciers are significantly losing mass with an increasing rate since at least ~1970, despite thick debris cover. The specific mass loss is 0.32 ± 0.08 m w.e. a?1, however, not higher than the global average. The spatial patterns of surface lowering can be explained by variations in debris-cover thickness, glacier velocity, and ice melt due to exposed ice cliffs and ponds.

  16. Longest time series of glacier mass changes in the Himalaya based on stereo imagery

    Science.gov (United States)

    Bolch, T.; Pieczonka, T.; Benn, D. I.

    2010-12-01

    Mass loss of Himalayan glaciers has wide-ranging consequences such as declining water resources, sea level rise and an increasing risk of glacial lake outburst floods (GLOFs). The assessment of the regional and global impact of glacier changes in the Himalaya is, however, hampered by a lack of mass balance data for most of the range. Multi-temporal digital terrain models (DTMs) allow glacier mass balance to be calculated since the availability of stereo imagery. Here we present the longest time series of mass changes in the Himalaya and show the high value of early stereo spy imagery such as Corona (years 1962 and 1970) aerial images and recent high resolution satellite data (Cartosat-1) to calculate a time series of glacier changes south of Mt. Everest, Nepal. We reveal that the glaciers are significantly losing mass with an increasing rate since at least ~1970, despite thick debris cover. The specific mass loss is 0.32 ± 0.08 m w.e. a-1, however, not higher than the global average. The spatial patterns of surface lowering can be explained by variations in debris-cover thickness, glacier velocity, and ice melt due to exposed ice cliffs and ponds.

  17. Surface characteristics of debris-covered glacier tongues in the Khumbu Himalaya derived from remote sensing texture analysis

    Science.gov (United States)

    Racoviteanu, Adina; Arnaud, Yves; Nicholson, Lindsay

    2013-04-01

    The delineation of debris-covered glaciers remains a challenge in optical remote sensing, due to the similarity of the spectral signature of debris-covered ice to surrounding lateral moraines, making it difficult to apply standard semi-automated algorithms commonly used for clean ice delineation. Furthermore, supraglacial debris exhibits considerable spatial variability in its characteristics such as debris cover thickness, particle size, thermal resistance and thermal conductivity. These properties are needed in order to map the extent of debris cover and to estimate ice melt under the debris cover or at the surface. In this study we evaluate the potential of texture analysis for detecting surface characteristics of debris-cover glacier tongues in the Khumbu Himalaya, using Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) and high-resolution Ikonos data. We focus on mapping supra-glacier lakes and exposed ice walls using texture analysis algorithms such as grey-level co-occurrence measures (GLCM), filtering, image segmentation, and particle boundaries. We compare the performance of various existing commercial software suitable for texture analysis such as ERDAS Objective, Aphelion, as well as public domain image display and analysis software used originally for medical analysis, notably Image SXM and ImageJ. Preliminary results based on geostatistics and GLCM measures show differences in surface roughness of debris cover when compared to surrounding ice-free moraines. We expand on these results and aim at developing a quasi-automated algorithm for extracting surface features, which will be used as input in an energy balance model for estimating melting under debris cover as well as surface ice melt.

  18. Heterogeneous Status of Glacial Terminal-Contacted Lakes in Himalayas Due to Different Geomorphology and Glacier Characters

    Science.gov (United States)

    Liu, Q.; Nie, Y.; Liu, S.

    2014-12-01

    Widespread expanding of glacial lakes around the Himalayas, which has led (or will lead) to hazard risks in their downstream valleys due to the potential glacial outburst flood (GLOF), has been widely reported during the past decades. Among all type of glacial lakes, those lakes contacted with the terminals of modern glaciers are generally found experienced most remarkable area increases. That is mostly due to the coupled processes, such as calving, between the lake growths and ice tongue retreats. Thermal absorption and convection of lake water are important for calving at the ice cliff or sub-marine melting under the supra-ponded water bodies. Currently, many larger moraine dammed lakes, e. g., Imja Tsho (Nepal) and Longbasaba Lake (China), are observed undergoing remarkable growths and synchronically with the rapid ice margin collapses due to calving. Some newly formed and rapidly growing supraglacial lakes are also identified on the debris-covered region of Himalayan glaciers, e. g., the Rongbuk Glacier (China), Ngozumpa Glacier (Nepal) and Thorthormi Glacier (Butan), which are speculated to experience accelerated expanding in the near future and finally developing as bigger terminal-calving lakes. However, not all such lake-glacier systems present the same scenes. After experienced the phases of rapid lake growth and terminal retreat, despite the contacting and calving still existing, the positions of the calving lines may be balanced by the positive advances of the ice tongue. We have observed several lakes with stagnation of growth or even shrinkage in lake area as the advance of the calving ice margin. The heterogeneous status of these ice-contacted glacial lakes are mainly due to the different local geomorphology (e. g., slope, lake-basin shape and valley aspect) and glacier characters (e. g., debris cover, velocity and mass balance). These related factors are important for both the prediction of lake and glacier changes and the evaluation of GLOF hazards in the future.

  19. Stress tolerance and genetic variability of phosphate-solubilizing fluorescent Pseudomonas from the cold deserts of the trans-Himalayas.

    Science.gov (United States)

    Vyas, Pratibha; Rahi, Praveen; Gulati, Arvind

    2009-08-01

    Nineteen efficient phosphate-solubilizing fluorescent Pseudomonas from the cold deserts of the trans-Himalayas were screened for stress tolerance against temperature, alkalinity, salinity, calcium salts, and desiccation. Phylogenetic analysis based on 16S rRNA gene sequencing placed these bacteria under three groups with fourteen strains in Group I including Pseudomonas trivialis and P. poae, two strains in Group II together with Pseudomonas kilonensis and P. corrugata, and three strains in Group III along with Pseudomonas jessenii and P. moraviensis. Genetic diversity assessed by ERIC and BOX-PCR revealed variability among strains belonging to the same phylogenetic groups. Cluster analysis based on the growth characteristics under regimes of different stress levels placed the strains into three distinct clusters displaying no correlation to their phylogenetic groups. Stress-tolerant strains differed in the level of decline in phosphate solubilization under increasing intensity of various stress parameters. The highest decrease occurred with 5% CaCO(3,) followed by 2.5% CaCO(3), pH 11, 5% NaCl, temperature of 37 degrees C, 40% PEG, 5% CaSO(4), 2.5% NaCl, 2.5% CaSO(4), pH 9 and temperature of 15 degrees C. Two strains belonging to Phylogenetic Group I exhibited higher phosphate solubilization at lower temperature. The results revealed that stress-tolerance ability was not limited to any particular phylogenetic group. Knowledge about the genetic variants of phosphate-solubilizing fluorescent Pseudomonas with potential for tolerance to desiccation, alkalinity, temperature, and salinity could be useful in understanding their ecological role under stressful environments of low phosphate availability. PMID:19319589

  20. Determination of Q ?( f) in Different Parts of Kumaon Himalaya from the Inversion of Spectral Acceleration Data

    Science.gov (United States)

    Joshi, A.; Kumar, P.; Mohanty, M.; Bansal, A. R.; Dimri, V. P.; Chadha, R. K.

    2012-10-01

    This paper presents the results of a modified two-step inversion algorithm approach to find S wave quality factor Q ?( f) given by J oshi (Bull Seis Soc Am 96:2165-2180, 2006). Seismic moment is calculated from the source displacement spectra of the S wave using both horizontal components. Average value of seismic moment computed from two horizontal components recorded at several stations is used as an input to the first part of inversion together with the spectra of S phase in the acceleration record. Several values of the corner frequency have been selected iteratively and are used as inputs to the inversion algorithm. Solution corresponding to minimum root mean square error (RMSE) is used for obtaining the final estimate of Q ?( f) relation. The estimates of seismic moment, corner frequency and Q ?( f) from the first part of inversion are further used for obtaining the residual of theoretical and observed source spectra which are treated as site amplification terms. The acceleration record corrected for the site amplification term is used for determination of seismic moment from source spectra by using Q ?( f) obtained from first part of inversion. Corrected acceleration record and new estimate of seismic moment are used as inputs to the second part of the inversion scheme which is similar to the first part except for use of input data. The final outcome from this part of inversion is a new Q ?( f) relation together with known values of seismic moment and corner frequency of each input. The process of two-step inversion is repeated for this new estimate of seismic moment and goes on until minimum RMSE is obtained which gives final estimate of Q ?( f) at each station and corner frequency of input events. The Pithoragarh district in the state of Uttarakhand in India lies in the border region of India and Nepal and is part of the seismically active Kumaon Himalaya zone. A network of eight strong motion recorders has been installed in this region since March, 2006. In this study we have analyzed data from 18 local events recorded between March, 2006 and October, 2010 at various stations. These events have been located using HYPO71 and data has been used to obtain frequency-dependent shear-wave attenuation. The Q ?( f) at each station is calculated by using both the north-south (NS) and east-west (EW) components of acceleration records as inputs to the developed inversion algorithm. The average Q ?( f) values obtained from Q ?( f) values at different stations from both NS and EW components have been used to compute a regional average relationship for the Pithoragarh region of Kumaon Himalaya of form Q ?( f) = (29 ± 1.2) f (1.1 ± 0.06).

  1. Plants of the Cerrado naturally selected by grazing sheep may have potential for inhibiting development of Haemonchus contortus larva.

    Science.gov (United States)

    Morais-Costa, Franciellen; Soares, Ana Cláudia Maia; Bastos, Gabriela Almeida; Nunes, Yule Roberta Ferreira; Geraseev, Luciana Castro; Braga, Fernão Castro; Dos Santos Lima, Walter; Duarte, Eduardo Robson

    2015-10-01

    Plant species naturally selected by sheep grazing in the Cerrado region of Brazil were assessed in vitro for activity against Haemonchus contortus. One year of observations showed the plant families in the region exhibiting greatest richness to be Fabaceae, Rubiaceae, Malpighiaceae, Bignoniaceae, Myrtaceae, and Annonaceae. Nine species commonly selected by grazing sheep showed variation in the selectivity index with respect to the dry and rainy seasons. Coproculture was conducted in five replicates of 11 treatments: ivermectin, distilled water, or dehydrated leaves of nine selected plant species administered at 333.3 mg g(-1) fecal culture. The dried powder of Piptadenia viridiflora and Ximenia americana leaves significantly reduced the number of infective larvae compared to the distilled water control. These species showed efficacy of over 85 % despite low concentrations of proanthocyanidin. High-performance liquid chromatography analyses of extracts of these plants showed major peaks of UV spectra characteristic of flavonoids. Those naturally selected plant species with high antihelminthic efficacy show promise for use in diet as an alternative control of H. contortus in sheep. PMID:26085457

  2. A retinoid X receptor (RXR)-selective retinoid reveals that RXR-α is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands

    International Nuclear Information System (INIS)

    Certain lipids have been shown to be ligands for a subgroup of the nuclear hormone receptor superfamily known as the peroxisome proliferator-activated receptors (PPARs). Ligands for these transcription factors have been used in experimental cancer therapies. PPARs heterodimerize and bind DNA with retinoid X receptors (RXRs), which have homology to other members of the nuclear receptor superfamily. Retinoids have been found to be effective in treating many types of cancer. However, many breast cancers become resistant to the chemotherapeutic effects of these drugs. Recently, RXR-selective ligands were discovered that inhibited proliferation of all-trans retinoic acid resistant breast cancer cells in vitro and caused regression of the disease in animal models. There are few published studies on the efficacy of combined therapy using PPAR and RXR ligands for breast cancer prevention or treatment. We determined the effects of selective PPAR and RXR ligands on established human breast cancer cell lines in vitro. PPAR-α and PPAR-γ ligands induced apoptotic and antiproliferative responses in human breast cancer cell lines, respectively, which were associated with specific changes in gene expression. These responses were potentiated by the RXR-selective ligand AGN194204. Interestingly, RXR-α-overexpressing retinoic acid resistant breast cancer cell lines were more sensitive to the effects of the RXR-selective compound. RXR-selective retinoids can potentiate the antiproliferative and apoptotic responses of breast cancer cell lines to PPAR ligands

  3. CD5 is A potential selecting ligand for B-cell surface immunoglobulin: a possible role in maintenance and selective expansion of normal and malignant B cells.

    Science.gov (United States)

    Pospisil, R; Silverman, G J; Marti, G E; Aruffo, A; Bowen, M A; Mage, R G

    2000-01-01

    Although the function of CD5 on B cells is unknown, previous studies suggested that CD5 interaction with V(H) framework regions of surface immunoglobulins (Igs) may contribute to survival and expansion of B cells. Here we used B-chronic lymphocytic leukemia (B-CLL) cells and transformed B-cell lines from normal and B-CLL patients to study CD5-Ig interactions. Immobilized Ig binds and permits isolation of CD5 from lysates of CD5-expressing cell lines. Immunoglobulins or Fab fragments of different V(H) families varied in their effectiveness as inhibitors of anti-CD5 staining of CLL cells, appendix and tonsil tissue sections. Human Ig also binds to purified recombinant CD5. We show here for the first time that the unconventional Ig-CD5 interaction maps to the extracellular CD5-D2 domain whereas conventional epitopes recognized by anti-CD5 antibodies are localized in the D1 domain of CD5. We propose that interactions of VH framework regions with CD5 as a ligand may maintain, select or expand normal, autoimmune or transformed B cells and also contribute to skewing of the normal V(H) repertoire. PMID:10674908

  4. The b-spacing values of white micas and their metamorphic implications in the Lesser Himalaya, central Nepal

    Science.gov (United States)

    Paudel, Lalu Prasad; Arita, Kazunori

    2006-06-01

    The Lesser Himalaya in central Nepal exposes a very wide section (>80 km) of very low- to low-grade metamorphic rocks. Metamorphic data from these rocks are relatively rare because of fine-grained nature of the rocks and lack of suitable assemblage for themobarometric calculations. In the present study, b-spacing measurements and compositional analyses were carried out on white micas in very low- to low-grade metapelites collected along the Kali Gandaki river valley and Tansen-Pokhara road sections to determine evidence of polymetamorphism and P-T conditions of metamorphism. The study showed that the Lesser Himalaya experienced at least two metamorphic events, one prior to the Upper Main Central Thrust (Upper MCT) activity (pre-Himalayan? or M 0) and the other during the Upper MCT activity (Neohimalayan or M 2). The M 0 produced celadonite-rich white micas defining the S 1(=S 0) foliation which pre-dates the Upper MCT event. The M 0 white micas were partially or completely re-equilibrated during M 2. The white micas recrystallized during M 2 are relatively celadonite-poor and define S 2 foliation. The M 2 was of an intermediate-P type (Barrovian-type) in the south of the Phalebas Thrust while it was of relatively high-T type in the north near the Upper MCT. The geothermal gradient varied from 22 °C km -1 in the south to 26 °C km -1 in the north. The northward increase in geothermal gradient is thought to be due to the heat transfer from hot Higher Himalaya or shear heating along the Upper MCT as suggested by Le Fort [Le Fort, P., 1975. Himalaya, the collided range: present knowledge of the continental arc. American Journal of Science 275A, 1-44. Arita, K., 1983. Origin of the inverted metamorphism of the Lower Himalayas, central Nepal. Tectonophysics 95, 43-60].

  5. Transport of sediments in Himalaya-Karakorum and its influence on hydropower plants; Sedimenttransportprozesse im Himalaya-Karakorum und ihre Bedeutung fuer Wasserkraftanlagen

    Energy Technology Data Exchange (ETDEWEB)

    Palt, S.M.

    2001-07-01

    In the present study the sediment transport processes in alpine mountain areas and their impact on hydropower development projects are investigated. The aim of the present work is to contribute to the understanding of the transport process system, which is characterized by high magnitude-low frequency - events, to ensure an appropriate layout of high head hydropower projects in mountain regions. The sediment transport in large areas in the macro scale is triggered by natural hazards, such as earthquakes, rock slides, earth movements, debris flows, glacial lake outbursts and floods. The basic principle of complex transport processes in this scale is described and explained on the example of the Himalaya-Karakorum-region. The sediment transport process in the smaller scale, so called meso scale, is investigated by means of extensive field measurements at river reaches of 16 different mountain rivers of a 80000 km{sup 2} large project area. The measurements include topographic survey works and measurements of discharge, bed load and suspended load. Since the conditions of mountain rivers in terms of size of bed material as well as available flow velocities can be considered as extreme, an appropriate bed load sampler named B-69 was developed, constructed and used in the field. Moreover the hydraulic as well as the sedimentological efficiency of the sampler was tested in the laboratory tests. Due to the nice performance of the bed load sampler B-69 at high flow velocities it might be useful for flood conditions in gravel-bed rivers in other parts of the world as well. Based on the results of the study the parameter of the river slope can be considered as the most important one for the characteristics of the morphology, the flow conditions, the bed stability as well as the bed load transport in steep mountain rivers. With increasing slope morphological structures in the longitudinal direction will develop from flat bed conditions. The so called step-pool-systems consist of a cascade of staircase local falls. Their distance in-between the falls as well as their height difference at the steps is strongly depending on the river slope. (orig.) [German] Die vorliegende Arbeit beschaeftigt sich mit den Sedimenttransportprozessen in alpinen Gebirgsregionen und deren Auswirkungen auf Wasserkraftanlagen. Ziel der Arbeit ist es, zum Verstaendnis des natuerlichen Sedimenttransportes mit der fuer Gebirgsregionen typischen Charakteristik von 'High Magnitude-Low Frequency - Prozessen' beizutragen, um eine den Transportverhaeltnissen geeignete Auslegung von geplanten Wasserkraftanlagen zu finden. Am Beispiel der Gebirgsregion des Himalaya-Karakorums werden die komplexen Transportvorgaenge im grossraeumigen Raum des Makromassstabes erlaeutert. Dabei wird auf die Massentransporte eingegangen, die durch Naturgefahren wie Erdbeben, Felsgleitungen, Erdrutsche, Muren, Gletscherbrueche und Hochwaesser ausgeloest werden. Der Schwerpunkt der Arbeit liegt in der Durchfuehrung von umfangreichen Naturmessungen im untergeordneten Raum des Mesomassstabes im Bereich von einzelnen Flussabschnitten. Die Naturmessungen umfassen morphologische und topographische Aufnahmen, Abfliessmessungen, Geschiebe- sowie Schwebstoffmessungen an 16 Gebirgsfluessen eines insgesamt 80000 km{sup 2} grossen Projektgebietes im Himalaya-Karakorum. Aufgrund der extremen Verhaeltnisse der Gebirgsfluesse der Region hinsichtlich vorhandener Korngroesse des Bettmaterials sowie die Groessenordnung der Fliessgeschwindigkeiten wurde fuer die Untersuchungen eigens der mobile Geschiebesammler B-69 entwickelt, gebaut und auf seine hydraulische und sedimentologische Effizienz hin geprueft. Der Einsatz des B-69 hat sich im Feld bewaehrt und ist fuer weitere Anwendungen bei Hochwasserereignissen in kiesfuehrenden Fluessen geeignet. Als massgebender Parameter zur Beschreibung der Morphologie, der Stroemung, der Sohlenstabilitaet und des Geschiebetransportes von Gebirgsfluessen im Mesomassstab konnte das Gefaelle I festgestellt werden. Das Gefaelle ist bestimmend fuer die Ausbildung d

  6. Selection of candidate container materials for the conceptual waste package design for a potential high level nuclear waste repository at Yucca Mountain

    Energy Technology Data Exchange (ETDEWEB)

    Van Konynenburg, R.A.; Halsey, W.G.; McCright, R.D.; Clarke, W.L. Jr. [Lawrence Livermore National Lab., CA (United States); Gdowski, G.E. [KMI, Inc., Albuquerque, NM (United States)

    1993-02-01

    Preliminary selection criteria have been developed, peer-reviewed, and applied to a field of 41 candidate materials to choose three alloys for further consideration during the advanced conceptual design phase of waste package development for a potential high level nuclear waste repository at Yucca Mountain, Nevada. These three alloys are titanium grade 12, Alloy C-4, and Alloy 825. These selections are specific to the particular conceptual design outlined in the Site Characterization Plan. Other design concepts that may be considered in the advanced conceptual design phase may favor other materials choices.

  7. Lack of Abuse Potential in a Highly Selective Dopamine D3 Agonist, PF-592,379, in Drug Self-Administration and Drug Discrimination in Rats

    OpenAIRE

    Collins, Gregory T; Butler, Paul; Wayman, Chris; Ratcliffe, Sian; Gupta, Paul; Oberhofer, Geoffrey; Caine, S. Barak

    2012-01-01

    Dopamine D3-preferring agonists are commonly used to treat Parkinson’s disease and restless leg syndrome; however, laboratory animal studies suggest that they may possess a moderate abuse potential. These studies aimed to compare the highly-selective, full D3 agonist PF-592,379 to that of the less selective D3 agonist 7-OH-DPAT, and the indirect dopamine agonist cocaine in drug self-administration and discrimination assays. Although rats readily acquired high rates of fixed ratio (FR)1 respon...

  8. Selection of candidate container materials for the conceptual waste package design for a potential high level nuclear waste repository at Yucca Mountain

    International Nuclear Information System (INIS)

    Preliminary selection criteria have been developed, peer-reviewed, and applied to a field of 41 candidate materials to choose three alloys for further consideration during the advanced conceptual design phase of waste package development for a potential high level nuclear waste repository at Yucca Mountain, Nevada. These three alloys are titanium grade 12, Alloy C-4, and Alloy 825. These selections are specific to the particular conceptual design outlined in the Site Characterization Plan. Other design concepts that may be considered in the advanced conceptual design phase may favor other materials choices

  9. AN ANALYSIS OF MARKET POTENTIAL ANALYSIS TOWARDS SMALL CAR SEGMENT WITH SPECIAL REFERENCE TO SELECTED CITIES IN TAMILNADU

    Directory of Open Access Journals (Sweden)

    V.SUBRAMANIAN

    2013-01-01

    Full Text Available In recent years small segment cars became more popular due to its low price and its attractive features. In Indian market the small segment cars have more welcome from all the parts of India. This research was carried to found the market potential to the small car industry in India For this study the structured questionnaire was carried and the study concluded with the 600 respondents. It shows that market potential for the small car segment in Indian consumers overwhelm and Indian customers are the potential buyers to the small car segment.

  10. Fluoxetine potentiation of methylphenidate-induced neuropeptide expression in the striatum occurs selectively in direct pathway (striatonigral) neurons

    OpenAIRE

    Vincent VAN WAES; Carr, Betsy; Beverley, Joel A.; Steiner, Heinz

    2012-01-01

    Concomitant therapies combining psychostimulants such as methylphenidate and selective serotonin reuptake inhibitors (SSRIs) are used to treat several mental disorders, including attention-deficit hyperactivity disorder/depression comorbidity. The neurobiological consequences of these drug combinations are poorly understood. Methylphenidate alone induces gene regulation that mimics partly effects of cocaine, consistent with some addiction liability. We previously showed that the SSRI fluoxeti...

  11. Potential Impact of Multi-Walled Carbon Nanotubes Exposure to the Seedling Stage of Selected Plant Species

    OpenAIRE

    Parvin Begum; Refi Ikhtiari; Bunshi Fugetsu

    2014-01-01

    Phytotoxicity is a significant consideration in understanding the potential environmental impact of nanoparticles. Abundant experimental data have shown that multi-walled carbon nanotubes (MWNTs) are toxic to plants, but the potential impacts of exposure remain unclear. The objective of the present study was to evaluate possible phytotoxicity of MWNTs at 0, 20, 200, 1000, and 2000 mg/L with red spinach, lettuce, rice, cucumber, chili, lady’s finger, and soybean, based on root and shoot growt...

  12. Macro Invertebrate Community from Sonamarg Streams of Kashmir Himalaya

    Directory of Open Access Journals (Sweden)

    A.R. Yousuf

    2011-01-01

    Full Text Available This study analyses a macroinvertebrate community survey for River Sindh and its tributary including Baltal, Yashmarg, Sonamarg and Thajwas Grar considering the extreme hydrological conditions linked with the seasonal low-flow period typical for some streams in this area. This study attempts to provide an overview of the macro invertebrate assemblages and physico-chemical variables of the River Sindh and its important tributary. Four study sites were selected from the River Sindh and its tributary including Baltal, Yashmarg, Sonamarg and Thajwas Grar for studying the ecological distribution of Macroinvertebrate assemblages. Totally, 33 taxa of macroinvertebrates were recorded from the two streams belonging to Mollusca-3 (Gastropoda-2 and Bivalvia-1, Annelida-1 and Arthropoda-29 (Insecta-29. Among insects Ephemeroptera (7, Trichoptera (6 and Diptera (13 dominated. Except Yashmrag all sites were found devoid of annelids while as the mollusks were found absent at Sonamarg. Highest values of Shannon Weiner Index were found at Yashmarg (2.42 and lowest at Sonamarg (1.99 while as highest and lowest Sorensen?s similarity coefficient were found between Baltal/Thajwas Grar (0.68 and Yashmarg/Thajwas Grar (0.39, respectively. A perusal of the data on physico-chemical characteristics showed that these streams were hard water type with high dissolved oxygen content. The ionic composition of the stream waters revealed the predominance of bicarbonate and calcium. Insecta dominated both qualitatively as well as quantitatively and the study revealed that the substrate compositions dominated by gravel, pebble and leaf litters are primary determinants of the invertebrate community structure recording maximum species diversity and abundance. Sample locations impacted by Amarnath yatris pilgrimage comparatively reflected slightly higher increase in nutrients than Thajwas Grar almost devoid of pilgrimage effect.

  13. Modelling glacier change in the Everest region, Nepal Himalaya

    Directory of Open Access Journals (Sweden)

    J. M. Shea

    2014-10-01

    Full Text Available In this study, we apply a glacier mass balance and ice redistribution model to simulate historical and future glacier change in the Everest region of Nepal. High-resolution temperature and precipitation fields derived from gridded APHRODITE data, and validated against independent station observations from the EVK2CNR network, are used to drive the historical model from 1961 to 2007. The model is calibrated against geodetically derived estimates of net glacier mass change from 1992 to 2008, termini position of four large glaciers at the end of the calibration period, average velocities observed on selected debris-covered glaciers, and total glacierized area. We integrate field-based observations of glacier mass balance and ice thickness with remotely-sensed observations of decadal glacier change to validate the model. Between 1961 and 2007, the mean modelled volume change over the Dudh Kosi basin is −6.4 ± 1.5 km3, a decrease of 15.6% from the original estimated ice volume in 1961. Modelled glacier area change between 1961 and 2007 is −101.0 ± 11.4 km2, a decrease of approximately 20% from the initial extent. Scenarios of future climate change, based on CMIP5 RCP4.5 and RCP8.5 end members, suggest that glaciers in the Everest region will continue to lose mass through the 21st century. Glaciers in the basin are concentrated between 5000 and 6000 m of elevation, and are thus expected to be sensitive to changes in temperature and equilibrium line altitude (ELA. Glacier volume reductions between −35 to −62% are possible by 2050, and sustained temperature increases to 2100 may result in total glacier volume losses of between −73 and −96%.

  14. Phenological attributes of Angelica glauca and A. archangelica expressed at two different climatic zones in Western Himalaya

    OpenAIRE

    Rajiv K. Vashistha; Jitendra S. Butola; B.P. Nautiyal; M.C. Nautiyal

    2010-01-01

    Angelica glauca Edgew. and A. archangelica Linn., are high value medicinal and aromatic plants of the Himalaya. The present study examined phenological attributes of these species under cultivation at two different climatic zones in Western Himalaya, Uttarakhand, India. Plants of both species were cultivated in Tungnath (TN), an alpine zone (3600 m asl) and in Pothivasa (PV), a temperate zone (2200 m asl). The results showed that the commencement and completion periods of phenophases, viz., g...

  15. Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins

    International Nuclear Information System (INIS)

    Nuclear reprogramming is critical for animal cloning and stem cell creation through nuclear transfer, which requires extensive remodeling of chromosomal architecture involving dramatic changes in chromatin-binding proteins. To understand the mechanism of nuclear reprogramming, it is critical to identify chromatin-binding factors specify the reprogramming process. In this report, we have developed a high-throughput selection method, based on T7 phage display and chromatin immunoprecipitation, to isolate chromatin-binding factors expressed in mouse embryonic stem cells using primary mouse embryonic fibroblast chromatin. Seven chromatin-binding proteins have been isolated by this method. We have also isolated several chromatin-binding proteins involved in hepatocyte differentiation. Our method provides a powerful tool to rapidly and selectively identify chromatin-binding proteins. The method can be used to study epigenetic modification of chromatin during nuclear reprogramming, cell differentiation, and transdifferentiation

  16. Polyphase (Miocene-Pleistocene?) slip on the South Tibetan Fault system in the Dhaulagiri Himalaya

    Science.gov (United States)

    McDermott, J. A.; Hodges, K.; van Soest, M. C.

    2009-12-01

    The major detachments of the South Tibetan fault system (STFS) define a physiographic transition that can be traced along most of the length of the Himalayan orogen. The STFS has been assigned an Early-Middle Miocene initiation age, but recent geomorphic, structural and thermochronologic studies suggest that extensional deformation may have continued into the Pliocene and even Pleistocene epochs along some strands. Our recent work in the Kali Gandaki and Myagdi valleys of central Nepal (28°30'N-28°40'N; 83°20'E-83°45'E) adds to the mounting evidence for young STFS displacement. . The previously unmapped “Larjung detachment” is a low-angle (~15-20°), north-dipping structure that crops out within Cambrian(?) greenschist-facies calc-silicate rocks of Tibetan Sedimentary Sequence in the Dhaulagiri Himalaya. This detachment is roughly 2 kilometers structurally above and less steeply dipping than the previously mapped basal structure of the STFS in the region, the Annapurna detachment (AD). Our observations in the Kali Gandaki and Myagdi valleys reveal that the Larjung detachment expresses as a 1- to 10-m thick, brittle-ductile, shear zone. In the Myagdi valley, ductile fabrics indicate oblique slip on this structure in the direction N62°E, with normal and dextral components. On the basis of structural similarities, we link the Larjung detachment to the Machhapuchhare detachment in the Modi Khola drainage and the Phu detachment in the Marsyandi drainage farther east in the Annapurna Himalaya. We have collected a suite of samples in both the Kali Gandaki and Myagdi valleys for low-temperature thermochronometry aimed at constraining the ages of various strands of the STFS in the Dhaulagiri Himalaya. Preliminary (U-Th)/He dating of single crystals of zircon and apatite below the Larjung detachment exhibit consistently young cooling ages (<3.4 Ma). We found no statistically significant evidence of a distinctive age discontinuity across the AD, implying that the amount of Quaternary slip on that structure documented by Hurtado et al. (2001) was too small to be expressed as a thermochronologic discontinuity. On the other hand, one apatite (U-Th)/He date obtained thus far from the hanging wall of the Larjung detachment (12.26±0.49 Ma (2SE)) is significantly older than all sample dates from its footwall. Hurtado et al. (2001) GSA Bulletin, v. 113, p. 222

  17. High resolution maping of the crustal architecture by ambient noise tomography in the North Western Himalaya

    Science.gov (United States)

    Kumar, N.; Aoudia, A.; Hazarika, D.; Yadav, D. K.

    2014-12-01

    A sizeable mid-crustal low velocity layer is mapped beneath the North-Western (NW) Himalaya and clear evidence for a decollement plane is reported. We performed ambient noise tomography for the NW Himalaya region using data of 31 broadband seismic stations. The ray paths sample the Himalayan region, the south Tibetan detachment zone and the Indo-Tsangpo suture zone, therefore covering the boundary regions of Indian and Eurasian plates to the South of the Karakoram fault. This part of the Himalayan region has witnessed devastating earthquakes such as Kashmir earthquake of 2005 and Kangra earthquake of 1905 along with many strong events. Rayleigh and Love waves data is utilized to extract dispersion curves for more than 500 paths for each wave. The spatial regional difference for group velocities are mapped for the periods in the range 4-40 sec, however most of the data are for period lower than 30 sec. The 2D tomography maps of fundamental mode highlight high lateral variations that may account for sub-surface tectonic deformation and variable crustal thicknesses. Larger variations are depicted for high period Rayleigh waves rather than Love waves and this mainly for the paths passing close to India-Tibet tectonic boundary. This study based on latest data gives new detail of sub-surface structural setup of the western part of Himalaya highlighting a low velocity mid-crustal layer characterized by an absence of lower crustal seismicity below decollment plane . A clear discontinuity within the physical properties mimics a possible decollement plane that could transfer sizeable earthquakes. Specifically a minimum value of Rayleigh wave velocity close to the decollement zone is reported and may likely correspond to mineral anisotropy while its existence to the lower part can be due to partial melting as per previous finding. The influence of Moho on the dispersion data suggests that this discontinuity is dipping towards north. However in the northern part close to India-Tibet plate tectonic boundary the Moho should be deeper than the efficiency of available data.

  18. Glacier dynamics of the Pamir-Karakoram-Himalaya region over the last 40 years

    Science.gov (United States)

    Gourmelen, N.; Dehecq, A.; Trouvé, E.

    2014-12-01

    Climate warming over the 20th century has caused drastic changes in mountain glaciers globally, and of the Himalayan glaciers in particular. The stakes are high; glaciers and ice caps are the largest contributor to the increase in the mass of the world's oceans, and the Himalayas play a key role in the hydrology of the region, impacting on the economy, food safety and flood risk. Partial monitoring of the Himalayan glaciers has revealed a mixed picture; while many of the Himalayan glaciers are retreating, in some cases locally stable or advancing glaciers in this region have also been observed. But recent controversies have highlighted the need to understand the glaciers dynamic and its relationship with climate change in the region. Earth Observation provides a mean for global and long-term monitoring of mountain glaciers' dynamics. In the frame of the Dragon program, a partnership between the European Space Agency (ESA) and the Chinese Center for Earth Observation (NRSCC), we begun a monitoring program aimed at quantifying multidecadal changes in glaciers' flow at the scale of the entire Himalayas and Karakoram from a 40 years' archive of Earth Observation. Ultimately, the provision of a global and time-sensitive glaciers velocity product will help to understand the evolution of the Himalayan glaciers in lights of glaciological (e.g. presence of debris-cover, surges, proglacial lakes) and climatic conditions. Here we present a region-wide analysis of annual and seasonnal glacier flow velocity covering the Pamir-Karakoram-Himalaya region obtained from the analysis of the entire archive of Landsat data. Over 90% of the ice-covered regions, as defined by the Randolph Glacier Inventory, are measured, with precision on the retrieved velocity of the order of 2 m/yr. We show that the first order temporal evolution of glacier flow mirrors the pattern of glacier mass balance. We observe a general decrease of ice velocity in regions of known ice mass loss, and a more complex patterns consisting of mixed acceleration and decrease of ice velocity in regions that are known to be affected by stable mass balance and surge-like behavior.

  19. Proposed nuclear weapons nonproliferation policy concerning foreign research reactor spent nuclear fuel: Appendix D, selection and evaluation of potential ports of entry. Volume 2

    International Nuclear Information System (INIS)

    This is an appendix to a draft Environmental Impact Statement (EIS) on a proposed nuclear weapons nonproliferation policy concerning foreign research reactor spent nuclear fuel. This appendix describes the process used by the Department of Energy in selecting the potential ports of entry analyzed in this EIS. In addition the appendix provides the basic information required to evaluate ports and port activities, and the potential environmental impacts (incident-free and accidents) associated with the receipt and handling of foreign research reactor spent nuclear fuel from vessels to intermodal transport in ports

  20. Early Auditory Evoked Potential Is Modulated by Selective Attention and Related to Individual Differences in Visual Working Memory Capacity

    OpenAIRE

    Giuliano, Ryan J.; Karns, Christina M.; Neville, Helen J.; Hillyard, Steven A

    2014-01-01

    A growing body of research suggests that the predictive power of working memory (WM) capacity for measures of intellectual aptitude is due to the ability to control attention and select relevant information. Crucially, attentional mechanisms implicated in controlling access to WM are assumed to be domain-general, yet reports of enhanced attentional abilities in individuals with larger WM capacities are primarily within the visual domain. Here, we directly test the link between WM capacity and...

  1. Selectivity in the potentiation of antibacterial activity of ?-peptide/?-peptoid peptidomimetics and antimicrobial peptides by human blood plasma

    DEFF Research Database (Denmark)

    Hein-Kristensen, Line; Knapp, Kolja M.

    2013-01-01

    Antimicrobial peptides (AMPs) are promising leads for novel antibiotics; however, their activity is often compromised under physiological conditions. The purpose of this study was to determine the activity of alpha-peptide/beta-peptoid peptidomimetics and AMPs against Escherichia coli and Staphylococcus aureus in the presence of human blood-derived matrices and immune effectors. The minimum inhibitory concentration (MIC) of two peptidomimetics against E. coli decreased by up to one order of magnitude when determined in 50% blood plasma as compared to MHB media. The MIC of a membrane-active AMP, LL-I/3, also decreased, whereas two intracellularly acting AMPs were not potentiated by plasma. Blood serum had no effect on activity against E. coli and neither matrix had an effect on activity against S. aureus. Unexpectedly, physiological concentrations of human serum albumin did not influence activity. Plasma potentiation was not mediated by an LL-37 analogue, lysozyme or hydrogen peroxide; however, plasma potentiation of activity was abolished when the complement system was heat-inactivated. Time-course experiments indicated that potentiation was due to plasma-mediated effects on bacterial cells prior to activities of peptidomimetics. The unexpected enhancement of antibacterial activity of peptidomimetics and AMPs under physiological conditions significantly increases the therapeutic potential of these compounds. (C) 2013 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

  2. Bio-active glass air-abrasion has the potential to remove resin composite restorative material selectively

    International Nuclear Information System (INIS)

    The aims of this study were to assess: (a) the chemistry, morphology and bioactivity of bio-active glass (BAG) air-abrasive powder, (b) the effect of three air-abrasion operating parameters: air pressure, powder flow rate (PFR) and the abrasive powder itself, on the selective removal of resin composite and (c) the required “time taken”. BAG abrasive particles were characterised using scanning electron microscopy-energy dispersive X-ray spectrometry (SEM-EDX) and Fourier-transform infrared spectroscopy (FTIR). Standardised resin composite restorations created within an enamel analogue block (Macor™) in vitro, were removed using air-abrasion undersimulated clinical conditions. 90 standardised cavities were scanned before and after resin composite removal using laser profilometry and the volume of the resulting 3D images calculated. Multilevel linear model was used to identify the significant factors affecting Macor™ removal. BAG powder removed resin composite more selectively than conventional air-abrasion alumina powder using the same operating parameters (p < 0.001) and the effect of altering the unit's operating parameters was significant (p < 0.001). In conclusion, BAG powder is more efficient than alumina in the selective removal of resin composite particularly under specific operating parameters, and therefore may be recommended clinically as a method of preserving sound enamel structure when repairing and removing defective resin composite restorations.

  3. Bio-active glass air-abrasion has the potential to remove resin composite restorative material selectively

    Energy Technology Data Exchange (ETDEWEB)

    Milly, Hussam [Biomaterials, Biomimetics and Biophotonics Research Group, Kings College London Dental Institute at Guy' s Hospital, King' s Health Partners, London (United Kingdom); Andiappan, Manoharan [Unit of Dental Public Health, Kings College London Dental Institute at Guy' s Hospital, King' s Health Partners, London (United Kingdom); Thompson, Ian [Biomaterials, Biomimetics and Biophotonics Research Group, Kings College London Dental Institute at Guy' s Hospital, King' s Health Partners, London (United Kingdom); Banerjee, Avijit, E-mail: avijit.banerjee@kcl.ac.uk [Biomaterials, Biomimetics and Biophotonics Research Group, Kings College London Dental Institute at Guy' s Hospital, King' s Health Partners, London (United Kingdom); Unit of Conservative Dentistry, King' s College London Dental Institute at Guy' s Hospital, King' s Health Partners, London (United Kingdom)

    2014-06-01

    The aims of this study were to assess: (a) the chemistry, morphology and bioactivity of bio-active glass (BAG) air-abrasive powder, (b) the effect of three air-abrasion operating parameters: air pressure, powder flow rate (PFR) and the abrasive powder itself, on the selective removal of resin composite and (c) the required “time taken”. BAG abrasive particles were characterised using scanning electron microscopy-energy dispersive X-ray spectrometry (SEM-EDX) and Fourier-transform infrared spectroscopy (FTIR). Standardised resin composite restorations created within an enamel analogue block (Macor™) in vitro, were removed using air-abrasion undersimulated clinical conditions. 90 standardised cavities were scanned before and after resin composite removal using laser profilometry and the volume of the resulting 3D images calculated. Multilevel linear model was used to identify the significant factors affecting Macor™ removal. BAG powder removed resin composite more selectively than conventional air-abrasion alumina powder using the same operating parameters (p < 0.001) and the effect of altering the unit's operating parameters was significant (p < 0.001). In conclusion, BAG powder is more efficient than alumina in the selective removal of resin composite particularly under specific operating parameters, and therefore may be recommended clinically as a method of preserving sound enamel structure when repairing and removing defective resin composite restorations.

  4. Early auditory evoked potential is modulated by selective attention and related to individual differences in visual working memory capacity.

    Science.gov (United States)

    Giuliano, Ryan J; Karns, Christina M; Neville, Helen J; Hillyard, Steven A

    2014-12-01

    A growing body of research suggests that the predictive power of working memory (WM) capacity for measures of intellectual aptitude is due to the ability to control attention and select relevant information. Crucially, attentional mechanisms implicated in controlling access to WM are assumed to be domain-general, yet reports of enhanced attentional abilities in individuals with larger WM capacities are primarily within the visual domain. Here, we directly test the link between WM capacity and early attentional gating across sensory domains, hypothesizing that measures of visual WM capacity should predict an individual's capacity to allocate auditory selective attention. To address this question, auditory ERPs were recorded in a linguistic dichotic listening task, and individual differences in ERP modulations by attention were correlated with estimates of WM capacity obtained in a separate visual change detection task. Auditory selective attention enhanced ERP amplitudes at an early latency (ca. 70-90 msec), with larger P1 components elicited by linguistic probes embedded in an attended narrative. Moreover, this effect was associated with greater individual estimates of visual WM capacity. These findings support the view that domain-general attentional control mechanisms underlie the wide variation of WM capacity across individuals. PMID:25000526

  5. Low- and intermediate level radioactive waste from Risoe, Denmark. Location studies for potential disposal areas. Report no. 1. Data, maps, models and methods used for selection of potential areas

    Energy Technology Data Exchange (ETDEWEB)

    Gravesen, P.; Nilsson, B.; Schack Pedersen, S.A.; Binderup, M.

    2011-07-01

    The low and intermediate level radioactive waste from Risoe (the nuclear reactor buildings plus different types of material from the research periods) and radioactive waste from hospitals and research institutes have to be stored in a final disposal in Denmark for at least 300 years. The Minister for Health and Prevention presented the background and decision plan for the Danish Parliament in January 2009. All political parties agreed on the plan. The investigation of geological deposits as potential waste disposals for high radioactive waste from nuclear power plants has earlier focused on deep seated salt deposits and basement rocks. Nevertheless, the Tertiary clays were mapped as well. In the present study, the salt diapirs and the salt deposits are not included. The present report briefly describes the existing data collections (including databases, maps and models), that are used during the work of selection of ca. 20 potentially suitable areas. Most of the information is stored in GEUS databases: Location of boreholes, borehole data, rock sediment and ground water compounds, maps, geophysical data and much more, but information is also collected from other institutions. The methods are described in more details (chapter 6) and this description is the direct background for the selection process, the characterisation of the 20 areas and for the final selection of the 2 or 3 most potential sites. (LN)

  6. Looking for pre-selected multiword units in an untagged corpus of written Italian: maximizing the potential of the search program DBT

    OpenAIRE

    Cignoni, Laura; Coffey, S

    1995-01-01

    In the course of research being carried out in the field of bilingual phraseology, the Italian Reference Corpus (IRC) was used as a potential source of contextualized examples for previously selected multiword units. In all, about 2000 items were looked for. These included both multiword lexical units and complete utterances. Before discussing the search program used and search techniques employed, it should be pointed out that the IRC is an untagged corpus. The user has no automatic help of ...

  7. Mutual recognition of parental and F1 lymphocytes. Selective abrogation of cytotoxic potential of F1 lymphocytes by parental lymphocytes

    OpenAIRE

    1980-01-01

    Four different combinations of F1 hybrid mice [(C57BL/10 X B10.A)F1, (C57BL/10 X B10.BR)F1, B6D2F1, and AKD2F1] were injected intravenously with spleen cells from parental strains. The T-cell-mediated cytotoxic potential of spleen cells from the injected F1 mice was assessed from 4 to 21 d later by in vitro sensitization with trinitrophenyl-modified parental or syngeneic F1 spleen cells (TNP-self) or with allogeneic spleen cells. The cytotoxic potential of the F1 mice to TNP-self as well as t...

  8. Anti-trypanosomal Activity of Potential Inhibitors of Trypanosoma brucei Glycolytic Pathway Enzymes Selected by Docking Studies

    Directory of Open Access Journals (Sweden)

    Clarisse Musanabaganwa

    2014-12-01

    Full Text Available Human African trypanosomiasis (HAT, a potentially fatal protozoan infection caused by tsetse-fl mediated transmission of Trypanosoma brucei (T. Brucei, is largely recognized as a neglected disease. The repertoire of drugs that is effective against the infection is limited and all drugs have several drawbacks including high level of toxicity, diffiult administration regimens, and the resurgence of resistance. At present the biology of the parasite is well studied and a number of technologies are now available which can aid in the identifiation of potential drug targets. This review identifies putative inhibitors of trypanosomal glycolytic enzymes.

  9. Surrogate species selection for assessing potential adverse environmental impacts of genetically engineered plants on non-target organisms

    Science.gov (United States)

    Most regulatory authorities require that developers of genetically engineered insect-resistant (GEIR) crops evaluate the potential for these crops to have adverse impacts on valued non-target organisms (NTOs), i.e., organisms not intended to be controlled by the trait. In many cases, impacts to NTOs...

  10. Selectable markers with potential activity against insects, plus other insect-oriented strategies for mycotoxin reduction in Midwest corn

    Science.gov (United States)

    Reduction of insect damage has the potential to greatly reduce the levels of mycotoxins in corn, as studies with Bt corn have shown. However, the large number of insect species involved necessitates the development of comprehensive insect control to most effectively utilize this strategy. One stra...

  11. Folate Conjugated Cellulose Nanocrystals Potentiate Irreversible Electroporation-induced Cytotoxicity for the Selective Treatment of Cancer Cells.

    Science.gov (United States)

    Colacino, Katelyn R; Arena, Christopher B; Dong, Shuping; Roman, Maren; Davalos, Rafael V; Lee, Yong W

    2015-12-01

    Cellulose nanocrystals are rod-shaped, crystalline nanoparticles that have shown prom-ise in a number of industrial applications for their unique chemical and physical properties. However, investigations of their abilities in the biomedical field are limited. The goal of this study is to show the potential use of folic acid-conjugated cellulose nanocrystals in the potentiation of irreversible electroporation-induced cell death in folate receptor (FR)-positive cancers. We optimized key pulse parameters including pulse duration, intensity, and incubation time with nanoparticles prior to electroporation. FR-positive cancer cells, KB and MDA-MB-468, were preincubated with cellulose nanocrystals (CNCs) conjugated with the targeting molecule folic acid (FA), 10 and 20 min respectively, prior to application of the optimized pulse electric field (PEF), 600 and 500 V/cm respectively. We have shown cellulose nanocrystals' ability to potentiate a new technique for tumor ablation, irreversible electroporation. Pre-incubation with FA-conjugated CNCs (CNC-FA) has shown a significant increase in cytotoxicity induced by irreversible electroporation in FR-positive cancer cells, KB and MDA-MB-468. Non-targeted CNCs (CNC-COOH) did not potentiate IRE when preincubated at the same parameters as previously stated in these cell types. In addition, CNC-FA did not potentiate irreversible electroporation-induced cytotoxicity in a FR-negative cancer cell type, A549. Without changing irreversible electroporation parameters it is possible to increase the cytotoxic effect on FR-positive cancer cells by exploiting the specific binding of FA to the FR, while not causing further damage to FR-negative tissue. PMID:24750004

  12. Potential Impact of Preoperative Magnetic Resonance Imaging of the Breast on Patient Selection for Accelerated Partial Breast Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Kuehr, Marietta, E-mail: marietta.kuehr@ukb.uni-bonn.de [Department of Obstetrics and Gynecology and Center of Integrated Oncology, University of Bonn, Bonn (Germany); Wolfgarten, Matthias; Stoelzle, Marco [Department of Obstetrics and Gynecology and Center of Integrated Oncology, University of Bonn, Bonn (Germany); Leutner, Claudia [Department of Radiology, Center of Integrated Oncology, University of Bonn, Bonn (Germany); Hoeller, Tobias [Department of Medical Statistics and Epidemiology, University of Bonn, Bonn (Germany); Schrading, Simone; Kuhl, Christiane; Schild, Hans [Department of Radiology, Center of Integrated Oncology, University of Bonn, Bonn (Germany); Kuhn, Walther; Braun, Michael [Department of Obstetrics and Gynecology and Center of Integrated Oncology, University of Bonn, Bonn (Germany)

    2011-11-15

    Purpose: Accelerated partial breast irradiation (APBI) after breast-conserving therapy is currently under investigation in prospective randomized studies. Multifocality and multicentricity are exclusion criteria for APBI. Preoperative breast magnetic resonance imaging (MRI) can detect ipsilateral and contralateral invasive tumor foci or ductal carcinoma in situ in addition to conventional diagnostic methods (clinical examination, mammography, and ultrasonography). The objective of this retrospective study was to evaluate the impact of preoperative MRI on patient selection for APBI. Methods and Materials: From 2002 to 2007, a total of 579 consecutive, nonselected patients with newly diagnosed early-stage breast cancer received preoperative breast MRI in addition to conventional imaging studies at the Bonn University Breast Cancer Center. In retrospect, 113 patients would have met the criteria for APBI using conventional imaging workup (clinical tumor size {<=}3 cm; negative axillary lymph node status; unifocal disease; no evidence of distant metastases; no invasive lobular carcinoma, ductal and lobular carcinoma in situ, or Paget's disease). We analyzed the amount of additional ipsilateral and contralateral tumor foci detected by MRI. Results: MRI detected additional tumor foci in 8.8% of patients eligible for APBI (11 tumor foci in 10 of 113 patients), either ipsilateral (n = 7, 6.2%) or contralateral (n = 4, 3.5%). In 1 patient, MRI helped detect additional tumor focus both ipsilaterally and contralaterally. Conclusions: Preoperative breast MRI is able to identify additional tumor foci in a clinically relevant number of cases in this highly selected group of patients with low-risk disease and may be useful in selecting patients for APBI.

  13. Historical Perspective on How and Why Switchgrass was Selected as a "Model" High-Potential Energy Crop

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Lynn L [ORNL

    2007-11-01

    A review of several publications of the Biofuels Feedstock Development Program, and final reports from the herbaceous crop screening trials suggests that there were several technical and non-technical factors that influenced the decision to focus on one herbaceous "model" crop species. The screening trials funded by the U.S. Department of Energy in the late 1980's to early 1990's assessed a wide range of about 34 species with trials being conducted on a wide range of soil types in 31 different sites spread over seven states in crop producing regions of the U.S. While several species, including sorghums, reed canarygrass and other crops, were identified as having merit for further development, the majority of institutions involved in the herbaceous species screening studies identified switchgrass as having high priority for further development. Six of the seven institutions included switchgrass among the species recommended for further development in their region and all institutions recommended that perennial grasses be given high research priority. Reasons for the selection of switchgrass included the demonstration of relatively high, reliable productivity across a wide geographical range, suitability for marginal quality land, low water and nutrient requirements, and positive environmental attributes. Economic and environmental assessments by Oak Ridge National Laboratory's Biofuels Feedstock Development Program staff together with the screening project results, and funding limitations lead to making the decision to further develop only switchgrass as a "model" or "prototype" species in about 1990. This paper describes the conditions under which the herbaceous species were screened, summarizes results from those trials, discusses the various factors which influenced the selection of switchgrass, and provides a brief evaluation of switchgrass with respect to criteria that should be considered when selecting and developing a crop for biofuels and bioproducts.

  14. Late Cenozoic exhumation and timing of the deformation front of the Kashmir Himalayas from U-Th/(He) thermochronometry

    Science.gov (United States)

    Gavillot, Y. G.; Meigs, A.; Stockli, D. F.; Malik, M. M.

    2013-12-01

    Apatite and zircon (U-Th)/He cooling ages are used to quantify the recent exhumation pattern associated with fault activity across the Kashmir Himalayas. Here we present data from thirty samples, totaling of 74 individual single-grain apatite and zircon dated aliquots. Cooling age data were collected from (1) molasse sediments of the Murree and Siwalik Formations from structures in the Sub-Himalayan belt (deformed foreland) and from (2) metasediments and plutonic rocks exhumed in the 'hinterland'. Structures of the Sub-Himalayan belt include the Suruin-Mastgarh anticline (SMA) at the deformation front, equivalent to the Himalayan Frontal thrust (HFT), and emergent local faults to the north (e.g. the Riasi thrust (RT)). In the hinterland, the Main Boundary (MBT) and Main Central (MCT) thrust sheets bound the Sub-Himalayan belt to the north. Apatite (U-Th)/He (AHe) cooling ages for the molasses sediments are consistently younger than the sediment age indicating that Sub-Himalayan belt samples are reset. Mean cooling age data based on the single grain populations from each sample ranges from ~1-10 Ma. Single grain and mean age probability density plots reveal a period of rapid cooling and exhumation between 1.8-2.75 Ma throughout the Sub-Himalaya. Distributed deformation associated with northward underthrusting along the MHT, and the onset of folding related to the SMA explains the regional exhumation of the Sub-Himalaya after ~2.75 Ma. Four samples from the hinterland MBT and MCT thrust sheets yield AHe cooling ages between ~5-21 Ma. Three of the samples have cooling ages between 4.7-7.2 Ma, likely coeval with activity of the MBT. Zircon (U-Th)/He (ZHe) samples from the hinterland are younger than the ages of the metasedimentary or plutonic source rocks. Most sample ages from the Sub-Himalaya are older or the same to the depositional age and are therefore detrital. Probability density plots of hinterland ZHe data show a pronounced spike in cooling between 16-21 Ma, with the same age cluster from the Sub-Himalayan samples, a period where MCT motion is well documented throughout the Himalaya. Cooling patterns across the Kashmir Himalayas thus suggest that distributed rather than localized break-forward deformation characterizes fault related exhumation for the Himalayan orogenic wedge development after ~20 Ma.

  15. Earthquake Risk Analysis and Science for Peace in Western/ Kashmir Himalayas - A Road Map for Transnational Subsurface Earth Imaging

    Science.gov (United States)

    Tandon, K.

    2006-12-01

    In light of immense human tragedy caused by the Kashmir earthquake of October 8, 2005, there is a need for transnational science for the assessment of future earthquake risks and understanding continental dynamics within the Western and Kashmir Himalayas. One can approach such a test to our society through understanding what causes these earthquakes in Kashmir in the first place in a rigorous manner and also try to determine how often do they happen in Western/ Kashmir Himalayas. Geophysical measurements (passive source, active source seismology, magnetotelluric measurements, Ground Penetrating Radar (GPR)) are imaging techniques for earth's deeper as well as shallow structure. When such imaging techniques are used on scales of earth's crust and beyond (~30 km to 100 km) and also on near the surface (~10 to100 meters) of the earth, it helps us understand both the processes for the origin and frequency of the earthquakes. Here, I will only concentrate on a road map for planning regional reflection seismology (active source seismology) surveys within the context of National Science Foundation (NSF) led Science for Peace Initiative primarily involving USA, India, and Pakistan. The proposal here is to initiate shallow and deep active source surveys in mega-population cities in Punjab and adjoining areas in Western Himalayas on either side of the political boundaries of India and Pakistan as separate ventures for first few years but a start for future collaboration. Once the core scientific teams are formed involving Indian, Pakistani, American, and scientists from other nations too, then the Indus Kohistan Seismic Zone in the Kashmir Himalayas should be the target for detailed geophysical and geological investigations. The idea presented here was first formed for the NSF sponsored International Karakoram-Kashmir Workshop that was supposed to be held in Islamabad (Pakistan), May 2006 with around 100 invitees from 10 nations for forming joint scientific initiatives. However, due to security concerns by the Government of Pakistan, the meeting was postponed at the 11th hour. Such political constraints invariably become the most dominant factor whether such bold endeavors can even be initiated, and the first order business is to convince the policy makers and scientists from India, Pakistan, USA, and other countries at all possible forums including AGU, the need and urgency for such transnational initiatives. The broader impacts are science and earthquake risk analysis in Western/ Kashmir Himalayas, lay framework for long-term policy decisions for earthquake hazards in Himalayas, and instrument for peace initiative.

  16. Similarities and differences of aerosol optical properties between southern and northern slopes of the Himalayas

    Directory of Open Access Journals (Sweden)

    C. Xu

    2013-08-01

    Full Text Available The Himalayas is located at the southern edge of the Tibetan Plateau, and it acts as a natural barrier for the transport of atmospheric aerosols, e.g. from the polluted regions of South Asia to the main body of the Tibetan Plateau. In this study, we investigate the seasonal and diurnal variations of aerosol optical properties measured at the three Aerosol Robotic Network (AERONET sites over the southern (Pokhara station and EVK2-CNR station in Nepal and northern (Qomolangma (Mt. Everest station for Atmospheric and Environmental Observation and Research, Chinese Academy of Sciences (QOMS_CAS in Tibet, China slopes of the Himalayas. While observations at QOMS_CAS and EVK2-CNR can generally be representative of a remote background atmosphere, Pokhara is an urban site with much higher aerosol load due to the influence of local anthropogenic activities. The annual mean of aerosol optical depth (AOD during the investigated period was 0.06 at QOMS_CAS, 0.04 at EVK2-CNR and 0.51 at Pokhara, respectively. Seasonal variations of aerosols are profoundly affected by large scale atmospheric circulation. Vegetation fires, peaking during April in the Himalayan region and northern India, contribute to a growing fine mode AOD at 500 nm at the three stations. Dust transported to these sites results in an increase of coarse mode AOD during the monsoon season at the three sites. Meanwhile, coarse mode AOD at EVK2-CNR is higher than QOMS_CAS from July to September, indicating the Himalayas blocks the coarse particles carried by the southwest winds. The precipitation scavenging effect is obvious at Pokhara, which can significantly reduce the aerosol load during the monsoon season. Unlike the seasonal variations, diurnal variations are mainly influenced by meso-scale systems and local topography. In general, precipitation can lead to a decrease of the aerosol load and the average particle size at each station. AOD changes in a short time with the emission rate near the emission source at Pokhara, while does not at the other two stations in remote regions. AOD increases during daytime due to the valley winds at EVK2-CNR, while this diurnal variation of AOD is absent at the other two stations. The surface heating influences the local convection, which further controls the vertical aerosol exchange and the diffusion rate of pollutions to the surrounding areas. The Himalayas blocks most of the coarse particles across the mountains. Fine and coarse mode particles are mixed to make atmospheric composition more complex on the southern slope in spring, which leads to the greater inter-annual difference in diurnal cycles of Ångström exponent (AE at EVK2-CNR than that at QOMS_CAS.

  17. Variations of the crustal thickness in Nepal Himalayas based on tomographic inversion of regional earthquake data

    Directory of Open Access Journals (Sweden)

    I. Koulakov

    2014-10-01

    Full Text Available We estimate variations of the crustal thickness beneath the Nepal Himalayas based on tomographic inversion of regional earthquake data. We have obtained a low-velocity anomaly in the upper part of the model down to depths of 40 to 80 km and proposed that the lower limit of this anomaly represents variations of the Moho depth. This statement was supported by results of synthetic modeling. The obtained variations of crustal thickness match fairly well with the free-air gravity anomalies: thinner crust patterns correspond to lower gravity values and vice versa. There is also some correlation with magnetic field: higher magnetic values correspond to the major areas of thicker crust. We propose that elevated magnetic values can be associated with more rigid segments of the incoming Indian crust which cause more compression in the thrust zone and leads to stronger crustal thickening.

  18. Direct evidence for a steep geotherm under conditions of rapid denudation, Western Himalaya, Pakistan

    Science.gov (United States)

    Winslow, David M.; Zeitler, Peter K.; Page Chamberlain, C.; Hollister, Lincoln S.

    1994-12-01

    Recent fluid-inclusion and 40Ar/39Ar cooling-age data show that currently exposed basement rocks in the Raikhot glacier valley of the Nanga Parbat-Haramosh massif, Pakistan Himalaya, were at temperatures of 350 ± 50 °C at depths of 6 ± 2 km (hydrostatic pressure correction). These data imply the presence of a steep thermal gradient in the upper crust at 1 Ma (29-100 °C/km) and denudation rates over the past 1.0 m.y. of 3-6 mm/yr, providing independent corroboration of previous estimates of rapid denudation at Nanga Parbat (4.5 mm/yr over 3.3 m.y.). Our data provide direct documentation of near-surface compaction of isotherms under conditions of rapid denudation, a result that has long been supported by thermal modeling.

  19. Population genetic study of Fagopyrum tataricum from Western Himalaya using ISSR markers.

    Science.gov (United States)

    Kishore, Garima; Pandey, Anjana; Dobhal, Rajendra; Gupta, Sanjay

    2013-10-01

    Inter-simple sequence repeat (ISSR) markers were used to analyze genetic diversity and relatedness of 15 germplasms of Fagopyrum tataricum. Samples representing 75 individuals were collected from a range of altitudes in the Western Himalaya. The 13 ISSR primers revealed 98.1% polymorphism among populations, whereas average polymorphism was extremely low (2.18%) within populations. The coefficient of population differentiation was 0.9750, with limited gene flow (N m) of 0.0128. The average PIC value of the ISSR markers was high (0.812), with a marker ratio of 0.65 and marker index of 6.66. The genetic diversity of F. tataricum significantly correlated with altitude and gene diversity, Shannon's index, and the percentage of polymorphic bands. The genetic diversity among populations showed broad genetic base and provided a developmental strategy for crop improvement. PMID:23743875

  20. Radon variations in an active landslide zone from Himalaya: A preliminary study

    International Nuclear Information System (INIS)

    The radon concentration was measured in soil and water samples from an active landslide zone in the Garhwal Himalaya. The landslide is compound in nature i.e. slump in the crown portion and debris slide in the lower part. The measured radon concentration varies from 3.1 to 18.3 Bq/l in water whereas in soil/debris samples it varies from 2.3 to 12.2 kBq/m3. The crown portion (upper portion) show higher radon values in comparison to distal portion. The higher radon concentration in crown portion may be because of the failure plane of landslide associated with high fracturing and crushing whereas, increased porosity of debris of slide does not allow radon to accumulate in soil and water in the lower portion. (author)

  1. Pictorial keys for predominant Bactrocera and Dacus fruit flies (Diptera: Tephritidae of north western Himalaya

    Directory of Open Access Journals (Sweden)

    C. S. Prabhakar

    2012-09-01

    Full Text Available A pictorial key for 13 species of fruit flies under 2 genera namely Bactrocera and Dacus of subfamily Dacinae (Diptera: Tephritidae is presented in this paper based on actual photographs of fruit flies collected from north western Himalaya of India during 2009-2010. Among these, Bactrocera diversa (Coquillett, Bactrocera scutellaris (Bezzi, Bactrocera tau (Walker, Bactrocera cucurbitae (Coquillett, Bactrocera zonata (Saunders, Bactrocera correcta (Bezzi, Bactrocera dorsalis (Hendel, Bactrocera latifrons (Hendel and Dacus ciliatus Loew are the pests of agricultural and horticultural ecosystems. Bactrocera latifrons, Bactrocera nigrofemoralis White and Tsuruta, Dacus longicornis Wiedemann and Dacus sphaeroidalis (Bezzi are the new records from the region of which host range has yet to be investigated. The pictorial keysdeveloped for these species will help the researchers for their easy and accurate identification.

  2. Repeated catastrophic valley infill following medieval earthquakes in the Nepal Himalaya.

    Science.gov (United States)

    Schwanghart, Wolfgang; Bernhardt, Anne; Stolle, Amelie; Hoelzmann, Philipp; Adhikari, Basanta R; Andermann, Christoff; Tofelde, Stefanie; Merchel, Silke; Rugel, Georg; Fort, Monique; Korup, Oliver

    2016-01-01

    Geomorphic footprints of past large Himalayan earthquakes are elusive, although they are urgently needed for gauging and predicting recovery times of seismically perturbed mountain landscapes. We present evidence of catastrophic valley infill following at least three medieval earthquakes in the Nepal Himalaya. Radiocarbon dates from peat beds, plant macrofossils, and humic silts in fine-grained tributary sediments near Pokhara, Nepal's second-largest city, match the timing of nearby M > 8 earthquakes in ~1100, 1255, and 1344 C.E. The upstream dip of tributary valley fills and x-ray fluorescence spectrometry of their provenance rule out local sources. Instead, geomorphic and sedimentary evidence is consistent with catastrophic fluvial aggradation and debris flows that had plugged several tributaries with tens of meters of calcareous sediment from a Higher Himalayan source >60 kilometers away. PMID:26676354

  3. Seismicity of Doon Valley, North West Himalaya, India: A Fractal Approach

    Science.gov (United States)

    Dimri, V. P.; Prakash, M. Ravi; Chamoli, A.

    2009-04-01

    Doon valley experienced severe tremors of Kangra earthquake (1905), the Uttarkashi earthquake (1991) and Chamoli earthquake (1999). The area falls in a tectonically active zone of the western sub-Himalaya with a complex geotectonic set up. In the present study, fractal analysis is carried out to understand the seismicity of the region using spatial distribution of earthquakes of the region and LANDSAT imageries of active lineament and drainage pattern of the area. The fractal dimension values for the lineament and drainage systems of the area are estimated as 1.63 and 1.82 respectively, which are close to the fractal Dimension (D2=1.73) of the epicentral distribution of earthquakes of the area. The analysis is described in terms of seismicity (b=1.19) for a tectonically active region.

  4. Radon anomalies and their correlation with microseismicity in N-W Himalaya

    International Nuclear Information System (INIS)

    Evidence for radon anomalies in soil-gas and groundwater as earthquake precursor phenomenon is recorded in Kangra and Chamba valleys of Himachal Pradesh, India based on micro-seismicity trends in N-W Himalaya. Radon monitoring is being carried out at Palampur, Jawalamukhi, Dalhousie and Chamba stations using emanometry for discrete measurements and alpha-logger technique for continuous recording of time-series radon data from June 1996 to September 1997. Radon anomalies in both type of data are correlated with some of the micro-earthquakes recorded during the time-window by the seismographic network of Indian Meteorological Department (IMD). A critical analysis is made of radon data to find confidence level and sensitivity of each recording station

  5. Evidence of Right Lateral Strike-slip Active Fault in Kangra Valley, NW Himalaya, India

    Science.gov (United States)

    Malik, J. N.; Sahoo, S.; Okumura, K.; Mohanty, A.; Naik, S. P.

    2013-12-01

    Kangra valley located in Himachal Pradesh, NW Himalaya falls under meizoseismal zone of 1905 Kangra earthquake (Mw=7.8). Till date no surface rupture has been reported, however few studies suggest that probable rupture along Jawalamukhi Thrust (JMT) located at south of Kangra valley. In present study we report newly identified right lateral strike-slip active fault trace striking WNW-ESE, named as 'Kangra Valley Fault'. The fault has displaced young alluvial fan surface and fluvial terrace in Kangra Valley. High resolution CARTOSAT - 1 data and CORONA photo interpretation revealed prominent offset of streams, alluvial fan surfaces and fluvial terraces. Ground Penetrating Radar (GPR) survey and trenches excavated across 1 m high fault scarp also revealed occurrence of paleo-earthquake during recent historic period. We have been able to trace this fault for a distance of ~40 km. Further result will play a vital role towards seismic hazard evaluation of this area.

  6. Seasonal succession of crustacean zooplankton in Wular Lake of the Kashmir Himalaya

    Directory of Open Access Journals (Sweden)

    Shah Javaid Ahmad

    2013-01-01

    Full Text Available The present study was undertaken on Wular Lake, a Ramsar Site in Kashmir Himalaya, to study the seasonal succession of crustacean zooplankton from September 2010 to August 2011. A total of 42 crustacean taxa belonging to Cladocera (23, Copepoda (16 and Ostracoda (3 were identified at five different sampling sites. Among the crustaceans, Cladocera was numerically the most dominant group at sites III, IV and V, followed by Copepoda at sites I and II. On an average basis total crustacean density ranged from 416 ind./l in winter to 1567.6 ind./l in summer. On the basis of Sorensen’s similarity index, study sites IV and V showed close similarity (88.13%.

  7. Tibetan garnet records early Eocene initiation of thickening in the Himalaya

    DEFF Research Database (Denmark)

    Smit, Matthijs Arjen; Hacker, Bradley

    2014-01-01

    Tectonic reconstructions of the Himalayan orogeny depend on the age at which crustal thickening commenced. To investigate this age, we analyzed garnet from middle crustal rocks exposed in the north Himalayan Mabja and Kangmar gneiss domes of Tibet using Lu-Hf geochronology. Garnet yielded Lu-Hf ages of 54–52 Ma in Mabja and 51–49 Ma in Kangmar samples. On the basis of microstructural and major element and rare earth element zoning observations, the Lu-Hf ages are interpreted as recording garnet growth during contractional deformation in the middle crust at 54.3 ± 0.6 Ma, followed by variable recrystallization during subsequent high-temperature ductile extension. The new Lu-Hf ages are the first to confirm that crustal thickening and contraction in the Tibetan Himalaya was broadly synchronous with the early Eocene collision between Greater India and the Eurasian plate

  8. Variations of the crustal thickness in Nepal Himalayas based on tomographic inversion of regional earthquake data

    Science.gov (United States)

    Koulakov, I.; Maksotova, G.; Mukhopadhyay, S.; Raoof, J.; Kayal, J. R.; Jakovlev, A.; Vasilevsky, A.

    2015-02-01

    We estimate variations of the crustal thickness beneath the Nepal Himalayas based on tomographic inversion of regional earthquake data. We have obtained a low-velocity anomaly in the upper part of the model down to depths of 40 to 80 km and proposed that the lower limit of this anomaly represents variations of the Moho depth. This statement was supported by results of synthetic modeling. The obtained variations of crustal thickness match fairly well with the free-air gravity anomalies: thinner crust patterns correspond to lower gravity values and vice versa. There is also some correlation with magnetic field: higher magnetic values correspond to the major areas of thicker crust. We propose that elevated magnetic values can be associated with more rigid segments of the incoming Indian crust which cause more compression in the thrust zone and lead to stronger crustal thickening.

  9. Rb-Sr geochronology of the rocks of the Himalayas, Eastern Nepal, (2)

    International Nuclear Information System (INIS)

    Rb-Sr isotopic measurements are made on the Makalu granite, which is one of leucocratic granite occurring sporadically in the high range of the Himalayas. The granite is intruded between the Himalayan gneiss and the Tethyan sediments. In this study, Rb-Sr analyses have been made on both whole rock and small sliced rock. The Rb-Sr isotopic analytical results on whole rock of the Makalu granite define the age of 92.7 +- 9.4 m.y. The analytical results on small slabs suggest that Sr isotopic redistribution occurred after the intrusion of the granite. The initial 87Sr/86Sr ratio of the Makalu granite is 0.7433 +- 0.0019 and is remarkably high. Such high ratio indicates that the granite originated from the remelting or partial remelting of old crustal materials such as Himalayan gneiss. (author)

  10. Rb-Sr ages of the biotite and muscovite of the Himalayas, eastern Nepal

    International Nuclear Information System (INIS)

    Rb-Sr ages of biotite from the southern flank of Mt. Everest, eastern Nepal, range from 14.1 to 1.3 m.y., the youngest biotite coexists with muscovite of 7.3 m.y. These different ages for different samples reflect the difference in cooling history related to the uplift of the Himalayas. The biotite ages decrease with increasing distance from the high mountain range, suggesting that the high range, i.e., the northern area, was uplifted earlier than the southern area. The relationship between the ages and altitutes of sampling sites indicates that the uplift rate of the northern area was 0.60 mm/yr. (author)

  11. Relative importance of fluvial and glacial erosion in shaping the Chandra Valley, western Himalaya, India

    Science.gov (United States)

    Eugster, P.; Scherler, D.; Thiede, R. C.; Codilean, A.; Strecker, M. R.

    2013-12-01

    In deeply incised, high-elevation orogens, such as the Himalaya, it is challenging to quantify the contribution of glaciers to long-term erosion and exhumation due to vigorous fluvial erosion and mass wasting. This is especially true for the humid sectors of the orogen. In the Himalaya, the majority of studies has been conducted in internal arid sectors of the orogen, where present-day ice coverage is low and glacial landforms and deposits are well preserved. The Chandra Valley of the greater Lahul area (NW-Himalaya), situated between the southern front of the range (bulk precipitation during summer) and the more arid Trans-Himalaya to the north (most precipitation during winter) is sensitive to fluctuations of the Indian Summer Monsoon and the Westerlies. In this region we intend to determine spatial and temporal variations in valley incision through fluvial and glacial erosion on different timescales by combining information obtained from cosmogenic radionuclide (CRN) dating of glacially-carved and striated surfaces, low-temperature thermochronometers, field mapping and morphometric analysis. A prominent feature in the upper Chandra Valley, also the headwater region of the Chenab River, is a large knickpoint in the present-day channel profile of the Chandra/Chenab River at an elevation of ~3900 m asl. This knickpoint spatially coincides with (1) a pronounced change in AFT ages along the course of the valley; (2) the joining of a tributary where one of the largest glaciers in the entire area is found; (3) a significant lithological break; and (4) a steep climatic gradient that accompanies the northward turn of the valley. Further knickpoints were found in tributary valleys of the Chandra Valley at approximately the same elevation of ~3900 m asl. Our field observations and preliminary CRN data suggest extensive glacial coverage of the upper Chandra Valley. Based on field evidence the minimum ice thicknesses for the main trunk glacier in the Chandra Valley must have been at least 700 m above the present-day valley bottom until ~15 ka. Our data confirm previous glacial chronological work in this area that also proposed that deglaciation of the Chandra Valley must have been rapid and accomplished within 15 ka, but additionally shows that the late glacial ice cover in the upper Chandra was more extensive than previously thought and also reached the Spiti Valley. Combining all preliminary results and observations, we hypothesize that glacial carving has been the first-order erosional agent during the Quaternary of all regions in Lahul above an elevation of 4100 m asl. Apatite fission-track ages suggest slower erosional exhumation in the more arid upper Chandra Valley. In this context a former blocking of the valley by the Bara Shigri glacier is possible and glacial processes may have outpaced fluvial erosion in the upper part of the Chandra Valley.

  12. FAIR FESTIVAL AND THERE RELIGIOUS BELIEF IN HIMACHAL HIMALAYA - A STUDY OF BUDI DIWALI OF NIRMAND

    Directory of Open Access Journals (Sweden)

    Hiramani Kashyap

    2014-06-01

    Full Text Available Himachal Pradesh is also known as the land of god and goddess. It is situated in lap of western Himalaya and full of natural and cultural beauty. Budi Diwali fair is held on Maghar Amawasya for three days in Village Nirmand of Kullu district. It is associated with the battle of Mahabharta which is said to have started on that day. It is also associated to commemorate the killing of two demons Dano and Asur, who resided at Nirmand in the form of snake. It starts with a brief recital of Mahabharta and story of Raja Bali through folk songs. Present study is based on that how this Budi Diwali fair is celebrated, what are the religious beliefs behind it and why this is important to celebrate in Nirmand area.

  13. Meiotic studies in some species of tribe Cichorieae (Asteraceae) from Western Himalayas.

    Science.gov (United States)

    Gupta, Raghbir Chand; Goyal, Henna; Singh, Vijay; Goel, Rajesh Kumar

    2014-01-01

    The present paper deals with meiotic studies in 15 species belonging to 6 genera of the tribe Cichorieae from various localities of Western Himalayas. The chromosome number has been reported for the first time in Hieracium crocatum (2n = 10) and Lactuca lessertiana (2n = 2x = 16). Further, intraspecific variability has been reported for the first time in H. umbellatum (2n = 2x = 10 and 2n = 6x = 54), Tragopogon dubius (2n = 2x = 14 and 2n = 4x = 28), and T. gracilis (2n = 2x = 14). The chromosome report of 2n = 2x = 10 in Youngia tenuifolia is made for the first time in India. Maximum numbers of the populations show laggards, chromosome stickiness, and cytomixis from early prophase to telophase-II, leading to the formation of aneuploid cells or meiocytes with double chromosome number. Such meiotic abnormalities produce unreduced pollen grains and the reduced pollen viability. PMID:25489603

  14. Increased late Pleistocene erosion rates during fluvial aggradation in the Garhwal Himalaya, northern India

    Science.gov (United States)

    Scherler, Dirk; Bookhagen, Bodo; Wulf, Hendrik; Preusser, Frank; Strecker, Manfred R.

    2015-10-01

    The response of surface processes to climatic forcing is fundamental for understanding the impacts of climate change on landscape evolution. In the Himalaya, most large rivers feature prominent fill terraces that record an imbalance between sediment supply and transport capacity, presumably due to past fluctuations in monsoon precipitation and/or effects of glaciation at high elevation. Here, we present volume estimates, chronological constraints, and 10Be-derived paleo-erosion rates from a prominent valley fill in the Yamuna catchment, Garhwal Himalaya, to elucidate the coupled response of rivers and hillslopes to Pleistocene climate change. Although precise age control is complicated due to methodological problems, the new data support formation of the valley fill during the late Pleistocene and its incision during the Holocene. We interpret this timing to indicate that changes in discharge and river-transport capacity were major controls. Compared to the present day, late Pleistocene hillslope erosion rates were higher by a factor of ∼2-4, but appear to have decreased during valley aggradation. The higher late Pleistocene erosion rates are largely unrelated to glacial erosion and could be explained by enhanced sediment production on steep hillslopes due to increased periglacial activity that declined as temperatures increased. Alternatively, erosion rates that decrease during valley aggradation are also consistent with reduced landsliding from threshold hillslopes as a result of rising base levels. In that case, the similarity of paleo-erosion rates near the end of the aggradation period with modern erosion rates might imply that channels and hillslopes are not yet fully coupled everywhere and that present-day hillslope erosion rates may underrepresent long-term incision rates.

  15. Geomorphological features of active tectonics and ongoing seismicity of northeastern Kumaun Himalaya, Uttarakhand, India

    Indian Academy of Sciences (India)

    Vivekanand Pathak; Charu C Pant; Gopal Singh Darmwal

    2015-08-01

    The northeastern part of Kumaun Lesser Himalaya, Uttarakhand, India, lying between the rupture zones of 1905, Kangra and 1934, Bihar–Nepal earthquakes and known as ‘central seismic gap’ is a segment of an active fault known to produce significant earthquakes and has not slipped in an unusually long time when compared to other segments. The studied section forms a part of this seismic gap and is seismically an active segment of the Himalayan arc, as compared to the remaining part of the Kumaun Lesser Himalaya and it is evident by active geomorphological features and seismicity data. The geomorphological features of various river valley transects suggest that the region had a history of tectonic rejuvenation which is testified by the deposition of various levels of terraces and their relative uplift, shifting and ponding of river channels, uplifted potholes, triangular facets on fault planes, fault scarps, etc. Further, the seismic data of five-station digital telemetered seismic network along with two stand alone systems show the distribution of earthquakes in or along the analyzed fault transects. It is observed that the microseismic earthquakes (magnitude 1.0–3.0) frequently occur in the region and hypocenters of these earthquakes are confined to shallow depths (10–20 km), with low stress drop values (1.0–10 bar) and higher peak ground velocity (PGV). The cluster of events is observed in the region, sandwiched between the Berinag Thrust (BT) in south and Main Central Thrust (MCT) in north. The occurrences of shallow focus earthquakes and the surface deformational features in the different river valley transect indicates that the region is undergoing neotectonic rejuvenation. In absence of chronology of the deposits it is difficult to relate it with extant seismicity, but from the geomorphic and seismic observations it may be concluded that the region is still tectonically active. The information would be very important in identifying the areas of hazard prone and also planning and designing of the socio-economic projects.

  16. Eocene to Oligocene retrogression and recrystallization of the Stak eclogite in northwest Himalaya

    Science.gov (United States)

    Kouketsu, Yui; Hattori, Kéiko; Guillot, Stéphane; Rayner, Nicole

    2016-01-01

    Highly retrogressed eclogite is present in the Stak massif located on the northern edge of the Indian continental margin in northern Pakistan. Garnet in foliated samples contains omphacite inclusions (Xjd = 0.33-0.40) and quartz inclusions and latter retain Raman spectroscopic evidence for high residual pressures up to 0.52 GPa. These garnet grains do not show apparent compositional zoning. By contrast, one sample contains euhedral grains of garnet with quartz inclusions that show residual pressures as low as 0.25 GPa. These garnet grains do not contain omphacite inclusions, and show different compositional zoning compared to the omphacite-bearing garnet. The metamorphic condition of this sample was estimated to be 1.0-1.4 GPa/650-710 °C using residual pressure values of quartz inclusions in garnets and the garnet-clinopyroxene geothermometer. The U-Pb ages of zircon grains range from 158 to 28 Ma with a cluster between at ca. 32 Ma, which is younger than that of the peak ultrahigh-pressure metamorphic ages of eclogitic massifs in the northwestern Himalaya, e.g. Kaghan and Tso Morari. We suggest that the retrogressed eclogitic rocks in the Stak massif were heated by nearby Nanga Parbat Haramosh massif at ca. 32 Ma, subsequent to peak eclogite facies conditions. During this heating, part of the eclogite was largely recrystallized to form euhedral garnet grains. These results suggest that the Stak massif resided at a lower crustal depth while other ultrahigh-pressure massifs were exhumed in western Himalaya.

  17. Long-term hydroclimatic variability in monsoon shadow zone of western Himalaya, India

    Energy Technology Data Exchange (ETDEWEB)

    Yadav, Ram R. [Birbal Sahni Institute of Palaeobotany, Lucknow (India)

    2011-04-15

    Tree-ring-width data of Himalayan cedar [Cedrus deodara (Roxb.) G. Don] from 11 homogeneous moisture stressed sites in the monsoon shadow zone of the western Himalaya were used to develop a mean chronology extending back to ad 1353. The chronology developed using Regional Curve Standardization method is the first from the Himalayan region of India showing centennial-scale variations. The calibration of ring-width chronology with instrumental precipitation data available from stations close to the tree ring sampling sites showed strong, direct relationship with March-April-May-June (MAMJ) precipitation. This strong relationship was used to supplement the instrumental precipitation data back to ad 1410. The precipitation reconstruction showed extended period of drought in fifteenth and sixteenth centuries. Increasingly pluvial conditions were recorded since eighteenth century, with the highest precipitation in the early part of the nineteenth century. The decreasing trend in reconstructed precipitation in the last decade of t