WorldWideScience
3

Confocal Imaging of Biological Tissues Using Second Harmonic Generation  

Energy Technology Data Exchange (ETDEWEB)

A confocal microscopy imaging system was devised to selectively detect Second harmonic signals generated by biological tissues. Several types of biological tissues were examined using this imaging system, including human teeth, bovine blood vessels, and chicken skin. All these tissues generated strong second harmonic signals. There is considerable evidence that the source of these signals in tissue is collagen. Collagen, the predominant component of most tissues, is known to have second order nonlinear susceptibility. This technique may have diagnostic usefulness in pathophysiological conditions characterized by changes in collagen structure including malignant transformation of nevi, progression of diabetic complications, and abnormalities in wound healing.

2000-03-06

4

Quantitative cerebral blood flow with Optical Coherence Tomography  

UK PubMed Central (United Kingdom)

Absolute measurements of cerebral blood flow (CBF) are an important endpoint in studies of cerebral pathophysiology. Currently no accepted method exists for in vivo longitudinal...Full Text Available

2010-02-01

6

Neuronal regulation of cochlear blood flow in the guinea-pig.  

UK PubMed Central (United Kingdom)

1. Previous studies have shown that electrical stimulation (ES) of the guinea-pig cochlea causes a neurally mediated increase in cochlear blood flow (CBF). It is known that the centrifugal neuronal...Full Text Available

1994-11-01

8

Blood flow quantification with MRI using the phase mapping method. Moeglichkeiten und Grenzen der Blutflussquantifizierung peripherer arterieller Gefaesse mit der MRT unter Anwendung des Phase-Mapping-Verfahrens  

Energy Technology Data Exchange (ETDEWEB)

MRT is able to demonstrate arteries while MR angiography can quantify blood flow by a non-invasive method. In the present paper blood flow measurements were carried out in four selected cases on the basis of phase mapping. In 3 patients with lesions in the pelvis or thigh, angiography was performed in order to localise the stenosis or occlusion and this was followed by qantitative blood flow measurements. The results showed that angiography may not always provide all necessary information concerning a haemodynamically significant stenosis. The method may also be used for quantifying blood flow in the renal arteries and that it has significant advantages over the colour Doppler method. (orig.).

1992-08-01

9

Autoradiographic study of regional distribution of gastric mucosal blood flow  

Energy Technology Data Exchange (ETDEWEB)

Iodo(/sup 14/C)antipyrine autoradiography was used to measure gastric mucosal blood flow in anesthetized rats and to study regional distribution. Blood flows of 61 +/- 8 ml.100 g-1.min-1 (means +/- SE) in corpus and 84 +/- 9 ml.100 g-1.min-1 in antral mucosa compared well with previously reported measurements by hydrogen clearance. Blood flow in the crests of corpus mucosal folds was significantly higher than in the valleys between folds, indicating that the greater susceptibility of the former areas to acute injury, documented in several studies, is not associated with a perfusion defect in the resting stomach. Corpus mucosal blood flow was also higher in the side walls of the stomach than in the greater curvature region, and in distal than in proximal locations. No systematic regional variations within antral mucosa ...

1988-04-01

10

Blood velocity measurement in human conjunctival vessels  

UK PubMed Central (United Kingdom)

The bulbar conjunctiva is one of the few areas in which blood flow in the peripheral vasculature can be directly and noninvasively observed in the human. Although extensive literature exists describing...Full Text Available

1981-12-01

11

Effect of external pressure on intramuscular blood flow at rest and after running  

Energy Technology Data Exchange (ETDEWEB)

Local blood flow in the thigh was measured with /sup 133/Xe clearance technique in eight male distance runners after compression with a foam rubber compress and a standard elastic bandage. Two degrees of compression were tested, and an initial experiment with rested subjects was followed by a similar experiment immediately after running. Maximum compression exerted a cutaneous pressure of 85 (+/- 8) mm Hg and caused an immediate cessation of intra-muscular blood flow in the compressed area. Moderate compression gave a cutaneous pressure of 40 (+/- 5) mm Hg and resulted in a reduction of blood flow by approximately 50%. During compression, there were no significant differences in the blood flow of rested subjects compared to subjects immediately after running. In acute soft tissue injuries, a maximum compression bandage ...

1987-10-01

12

Dynamic Deformation and Recovery Response of Red Blood Cells to a Cyclically Reversing Shear Flow: Effects of Frequency of Cyclically Reversing Shear Flow and Shear Stress Level  

UK PubMed Central (United Kingdom)

Dynamic deformation and recovery responses of red blood cells (RBCs) to a cyclically reversing shear flow generated in a 30-μm clearance, with the peak shear stress of 53, 108,...Full Text Available

2006-09-01

13

Purinergic receptors in the splanchnic circulation  

UK PubMed Central (United Kingdom)

There is considerable evidence that purines are vasoactive molecules involved in the regulation of blood flow. Adenosine is a well known vasodilator that also acts as a modulator of the response to...Full Text Available

2008-09-01

14

Multi-Harmonic RF Control System for J-PARC RCS  

CERN Document Server

Multi-Harmonic RF Control System for J-PARC RCS

2003-01-01

15

Drug detection in breath: effects of pulmonary blood flow and cardiac output on propofol exhalation  

British Library Electronic Table of Contents (United Kingdom)

Breath analysis could offer a non-invasive means of intravenous drug monitoring if robust correlations between drug concentrations in breath and blood can be established. In this study, propofol blood and breath concentrations were determined in an animal model under varying physiological conditions. Propofol concentrations in breath were determined by means of two independently calibrated analytical methods: continuous, real-time proton transfer reaction mass spectrometry (PTR-MS) and discontinuous solid-phase micro-extraction coupled with gas chromatography mass spectrometry (SPME-GC-MS). Blood concentrations were determined by means of SPME-GC-MS. Effects of changes in pulmonary blood flow resulting in a decreased cardiac output (CO) and effects of dobutamine administration resulting in...

2011-01-01

16

Effects of the. cap alpha. -adrenoceptor antagonists phentolamine, phenoxybenzamine, and Idazoxan on sympathetic blood flow control in the periodontal ligament of the cat  

Energy Technology Data Exchange (ETDEWEB)

Blood flow changes in the periodontal ligament (PDL) were measured indirectly by monitoring the local clearance of /sup 125/I/sup -/ during electric sympathetic nerve stimulation or close intra-arterial infusions of either noradrenaline (NA) or adrenaline (ADR) before and after administration of phentolamine (PA), phenoxybenzamine (PBZ) or Idazoxan (RX). At the doses used in the present study, PA was the only antagonist that significantly reduced the blood flow decrease seen on activation of sympathetic fibers, although PBZ also reduced this response. Idazoxan, however, did not induce the consistent effect on blood flow decreases seen on sympathetic activation. All three ..cap alpha..-adrenoceptor antagonists almost abolished the effects of exogenously administered NA and ADR. The results suggest the presence of functional post-junctional adrenoceptors of both ...

1988-01-01

17

Flow-induced changes in pial artery compliance registered with a non-invasive method in rabbits  

British Library Electronic Table of Contents (United Kingdom)

Aim: This study was performed: 1) to assess the relationship between blood flow velocity in the internal carotid artery (CBFICA) and pial artery pulsation (cc-TQ) and 2) to evaluate flow-induced changes in pial artery compliance. Methods: Experiments were performed on 10 crossbred male rabbits. Heart rate (HR), blood pressure (BP), left ventricle ejection fraction (LVEF), CBFICA, the systolic-diastolic blood volume fraction in the brain circulation (CBFSDF) and cc-TQ were recorded after glucagon and acetazolamide administration. cc-TQ was measured with near-infrared transillumination back scattering sounding (NIR-T/BSS), LVEF and CBFSDF with gated scintigraphy and BP and CBFICA with electromagnetic pressure and flow transducers, respectively. Doses of drugs were chosen to exert a haemodyna...

2011-01-01

18

A critical study of poiseuille flow of couple stress fluid with applications to blood flow  

Science.gov (United States)

It is shown that the method used for comparing theoretical and experimental results is erroneous and the values of the couple stress parameters obtained for blood flow are incorrect. A method for determining the couple stress parameters is presented. The computational work in the improved method is considerably less. It is observed that both the couple stress parameters are functions of concentration. An empirical relation between concentration and the stress parameters is obtained. The shear viscosity and non-dimensional axial velocity are functions of concentration. Some uses of determining the values of the couple stress parameters are suggested.

1981-01-01

19

Technetium complexes as potential brain imaging agents  

International Nuclear Information System (INIS)

Single photon tomography using lipophilic tracers provides tomographic representations of regional blood flow. To penetrate a healthy blood-brain barrier requires that radiotracers either are fat-soluble or have an affinity for one of the selective blood-brain barrier transport systems. In recent years there has been an increasing interest to explore the ideal physical characteristics of "9"9"mTc for diagnostic problems of brain diseases. The development of radiopharmaceuticals for brain imaging including the intensively studied "9"9"mTc-propyleneamineoxime derivatives is discussed. (author).

20

Estimation of parameters affecting the uptake of sup(99m)Tc-methylenediphosphonate in rat femur with model simulation  

Energy Technology Data Exchange (ETDEWEB)

The uptake of sup(99m)Tc-methylenediphosphonate (MDP) in different parts of rat femur was simulated using a local three-space model for tracer transfer. The model consisted of bone blood, bone ECF-space and space for tracer deposition. The measured sup(99m)Tc-MDP concentration in the systemic blood and the local bone blood flow measured by /sup 131/I-macroaggregated albumin microspheres were used as input parameters. The measured blood flow values were 6.3, 3.1 and 15.3 ml/100 g/min for proximal, middle and distal femur, respectively. the model parameters that gave the best fit to measured sup(99m)Tc-MDP uptake curves in computer simulation showed that bone blood flow, volume of ECF-space, permeability surface area product and accretion constant from ECF-space to space for tracer deposition were highest in distal and ...

1985-01-01

21

Estimation of parameters affecting the uptake of sup(99m)Tc-methylenediphosphonate in rat femur with model simulation  

International Nuclear Information System (INIS)

The uptake of sup(99m)Tc-methylenediphosphonate (MDP) in different parts of rat femur was simulated using a local three-space model for tracer transfer. The model consisted of bone blood, bone ECF-space and space for tracer deposition. The measured sup(99m)Tc-MDP concentration in the systemic blood and the local bone blood flow measured by "1"3"1I-macroaggregated albumin microspheres were used as input parameters. The measured blood flow values were 6.3, 3.1 and 15.3 ml/100 g/min for proximal, middle and distal femur, respectively. the model parameters that gave the best fit to measured sup(99m)Tc-MDP uptake curves in computer simulation showed that bone blood flow, volume of ECF-space, permeability surface area product and accretion constant from ECF-space to space for tracer deposition were highest in distal and lowest ...

22

Redistribution of pulmonary blood flow impacts thermodilution-based extravascular lung water measurements in a model of acute lung injury  

UK PubMed Central (United Kingdom)

BackgroundStudies using transthoracic thermodilution have demonstrated increased extravascular lung water (EVLW) measurements attributed to progression of edema and...Full Text Available

2009-11-01

23

Radionuclide angiocardiography in the diagnosis of congenital heart disorders.  

UK PubMed Central (United Kingdom)

Radionuclide angiocardiography provides a noninvasive assessment of cardiac function and blood flow through the heart and lungs. During the past three years, this procedure has been used at the Duke...Full Text Available

1981-06-01

24

Properties of single nerve fibres that evoke blood flow changes in cat dental pulp  

UK PubMed Central (United Kingdom)

Single nerve fibres innervating tooth pulp were isolated from filaments dissected from the inferior alveolar nerve in 17 anaesthetized cats. The fibres were studied to determine whether electrical stimulation...Full Text Available

2002-08-01

25

Local inhibition of nitric oxide generation in man reduces blood flow in finger pulp but not in hand dorsum skin.  

UK PubMed Central (United Kingdom)

1. Nitric oxide generation is important in the regulation of resistance vessel tone. Until now, however, there has been no evidence of such a role for basal generation of nitric oxide in the skin microcirculation...Full Text Available

1996-01-15

26

JAMA Patient Page: Cardiopulmonary Resuscitation (CPR)  

Science.gov (United States)

... of the American Medical Association JAMA PATIENT PAGE Cardiopulmonary Resuscitation W hen the heart stops beating (cardiac arrest), ... circulation (blood flow) returns or is restored. Providing cardiopulmonary resuscitation ( CPR ) is a way to keep some circulation ...

27

Elevated BMI Is Associated With Decreased Blood Flow in the Prefrontal Cortex Using SPECT Imaging in Healthy Adults  

UK PubMed Central (United Kingdom)

Obesity is a risk factor for stroke and neurodegenerative disease. Excess body fat has been linked to impaired glucose metabolism, insulin resistance, and impulsivity and may be a precursor to decline...Full Text Available

2011-05-01

28

Doppler imaging using spectrally-encoded endoscopy  

UK PubMed Central (United Kingdom)

The capability to image tissue motion such as blood flow through an endoscope could have many applications in medicine. Spectrally encoded endoscopy (SEE) is a recently introduced technique...Full Text Available

2008-09-15

29

Blood Flow and Pressure Telemetry.  

Science.gov (United States)

The major emphasis of this past year's research effort toward characterizing the responses of the cardiovascular system of the military working dog has been to obtain renal hemodynamic information from dogs involved in various stages of obedience, scoutin...

1973-01-01

30

ADEPT - Abnormal Doppler Enteral Prescription Trial  

UK PubMed Central (United Kingdom)

BackgroundPregnancies complicated by abnormal umbilical artery Doppler blood flow patterns often result in the baby being born both preterm and growth-restricted. These babies are...Full Text Available

31

Diabetic patients have abnormal cerebral autoregulation during cardiopulmonary bypass  

Energy Technology Data Exchange (ETDEWEB)

We tested the hypothesis that insulin-dependent diabetic patients with coronary artery bypass graft surgery experience altered coupling of cerebral blood flow and oxygen consumption. In a study of 23 patients (11 diabetics and 12 age-matched controls), cerebral blood flow was measured using 133Xe clearance during nonpulsatile, alpha-stat blood gas managed cardiopulmonary bypass at the conditions of hypothermia and normothermia. In diabetic patients, the cerebral blood flow at 26.6 +/- 2.42 degrees C was 25.3 +/- 14.34 ml/100 g/min and at 36.9 +/- 0.58 degrees C it was 27.3 +/- 7.40 ml/100 g/min (p = NS). The control patients increased cerebral blood flow from 20.7 +/- 6.78 ml/100 g/min at 28.4 +/- 2.81 degrees C to 37.6 +/- 8.81 ml/100 g/min at 36.5 +/- 0.45 degrees C (p less than or equal to 0.005). ...

1990-11-01

32

Visualization of disturbed flow with spin-echo and cine MR imaging  

International Nuclear Information System (INIS)

MR images of steady and pulsatile disturbed flow, obtained with use of flow-compensated spin-echo (SE) and cine pulse sequences, revealed excellent flow visualization in three dimensions. Phantoms, built from molds of actual blood vessels, reproduced laminar, disturbed, or turbulent flow. Video recording (VR), performed under conditions equivalent to those of the MR experiments, showed separation zones identical to those seen on SE images. Pulsatile flow studies showed complex patterns of vortical flow on cine images and VR. Varying pulse sequence details changed contrast but not flow patterns. The validation of MR observations by VR has implications for clinical cine imaging and low abnormal signals observed on MR angiograms.

33

Mapping of local cerebral blood flow with stable xenon-enhanced CT and the curve-fitting method of analysis  

Energy Technology Data Exchange (ETDEWEB)

A noninvasive method is described for estimating local cerebral blood flow (LCBF) and local partition coefficients by means of computed tomographic scanning during inhalation of 30% stable xenon gas in oxygen. Time-dependent xenon concentrations in arterial blood and brain tissue during the wash-in and washout phases are used to calculate partition coefficients and LCBF values by means of a least-squares curve-fitting analysis. Control values for partition coefficient and LCBF obtained from control subjects with minor head trauma in the chronic stage were compatible with those in several past reports, and reproducibility was satisfactory. The theoretic grounds underlying this new method of curve-fitting analysis are discussed.

1988-07-01

34

Mapping of local cerebral blood flow with stable xenon-enhanced CT and the curve-fitting method of analysis  

International Nuclear Information System (INIS)

A noninvasive method is described for estimating local cerebral blood flow (LCBF) and local partition coefficients by means of computed tomographic scanning during inhalation of 30% stable xenon gas in oxygen. Time-dependent xenon concentrations in arterial blood and brain tissue during the wash-in and washout phases are used to calculate partition coefficients and LCBF values by means of a least-squares curve-fitting analysis. Control values for partition coefficient and LCBF obtained from control subjects with minor head trauma in the chronic stage were compatible with those in several past reports, and reproducibility was satisfactory. The theoretic grounds underlying this new method of curve-fitting analysis are discussed.

35

Isolation of fetal DNA from nucleated erythrocytes in maternal blood  

Energy Technology Data Exchange (ETDEWEB)

Fetal nucleated cells within maternal blood represent a potential source of fetal genes obtainable by venipuncture. The authors used monoclonal antibody against the transferrin receptor (TIR) to identify nucleated erythrocytes in the peripheral blood of pregnant women. Candidate fetal cells from 19 pregnancies were isolated by flow sorting at 12 1/2-17 weeks gestation. The DNA in these cells was amplified for a 222-base-pair (bp) sequence present on the short arm of the Y chromosome as proof that the cells were derived from the fetus. The amplified DNA was compared with standardized DNA concentrations. In the case of the female fetus, DNA prepared from samples at 32 weeks of gestation and cord blood at delivery also showed the presence of the Y chromosomal sequence, suggesting Y sequence mosaicism or translocation. In 10/12 cases where the 222-bp band was absent, the fetuses were female. Thus, they were ...

1990-05-01

36

Model of blood-brain transfer of oxygen explains nonlinear flow-metabolism coupling during stimulation of visual cortex.  

DEFF Research Database (Denmark)

The coupling between cerebral metabolic rate of oxygen (CMRO2) and blood flow (CBF) in response to visual stimulation was evaluated by means of a model of oxygen delivery. The model predicted a nonlinear relationship between stimulus-evoked changes of oxygen consumption and blood flow. The magnitude of the CMRO2/CBF ratio index (IO2) was used to indicate the degree of flow-metabolism coupling prevailing in specific areas of the brain during physiological stimulation. Therefore, the index provided a measure of the blood oxygenation level dependent (BOLD) magnetic resonance contrast. To evaluate the changes of IO2 in response to visual stimulation, the model was applied to the effect of a changing flicker rate of a visual stimulus on the magnitudes of CBF, CMRO2, and oxygen diffusion capacity, in the human brain. Positron emission tomography (PET) was used to ...

2000-01-01

37

Analysis of even harmonics generation in an isolated electric power system  

British Library Electronic Table of Contents (United Kingdom)

Harmonics bred from loads are mainly odd order because the current waveforms have half-wave symmetry. Since the even harmonics are negligibly small, they generally are not measured in electric power systems. However, even harmonics were measured at a 500/275/154 kV substation in Hokuriku Electric Power Company after a transmission line fault was corrected. The even harmonics caused malfunctions of protective digital relays because the relays used 4th harmonics at the input filter as the automatic supervisory signal. This paper describes mechanisms of generation of the even harmonics by comparing the measured waveforms with the ATP-EMTP simulation results. Analysis of these results has clearly shown that there are three different mechanisms of generation of even harmonics. The first mechani...

2009-01-01

38

Quantification of the local glucose utilization and local blood flow in the heart of the awake rat using the /sup 14/C-2-deoxyglucose and /sup 14/C-iodoantipyrine methods  

Science.gov (United States)

Local cardiac glucose utilization (LCarGU) was quantified in the rat heart according to the Sokoloff model and local cardiac blood flow (LCarBF) according to the /sup 14/C-iodoantipyrine method. For quantitative autoradiography calibration curves for heart slices were performed. They differed from the brain calibration curves by 8%. The lumped constant was 0.377 in isolated working hearts. LCarGU and LCarBF could then be quantified in awake rats. At different locations mean LCarGU of different hearts varied from 85 to 200 ..mu..moles/100g/min and mean LCarBF from 390 to 831 ml/100g/min. The ratio subendocardial/subepicardial glucose utilization or blood flow was not systematically different from 1. The results indicate that glucose can be an important fuel in the heart of the awake rat, although its contribution to overall metabolism varies from animal to animal.

1986-03-05

39

Hemodynamic characterization of chronic bile duct-ligated rats: effect of pentobarbital sodium  

International Nuclear Information System (INIS)

Systemic and splanchnic hemodynamics of the chronic bile duct-ligated rat were characterized by radioactive microspheres. Conscious and pentobarbital sodium-anesthetized, bile duct-ligated and sham-operated rats had cardiac output and regional organ blood flows determined. The conscious bile duct-ligated rat compared with the sham-operated showed a hyperdynamic circulation with an increased cardiac output and portal tributary blood flow. Pentobarbital sodium anesthesia induced marked hemodynamic changes in both sham-operated and bile duct-ligated rats. The latter group was especially sensitive to its effects; thus, comparison of cardiac output and portal tributary blood flow between anesthetized bile duct-ligated and sham-operated rats showed no significant differences. The authors conclude that the rat with cirrhosis due to chronic bile duct ligation is an ...

40

Evaluation of craniosynostosis surgery. Technetium-99m-HMPAO SPECT cerebral blood flow study in children with craniosynostosis  

International Nuclear Information System (INIS)

Premature fusion of multiple cranial sutures has been associated with increased intracranial pressure and the potential for mental impairment. Isolated craniosynostosis, however, is considered a benign condition primarily reconstructed for aesthetic purposes. A comparative analysis, to assess the differences between pre- and post operatory cerebral perfusion of patients who underwent surgery for simple cranisynostosis, was performed using single positron emission computed tomography ''SPECT'' Images. Cerebral blood flow studies were performed using "9"9"mTc-HMPAO SPECT in children with simple cranisynotoses. The subjects were 8 children with craniosynostosis (age, 2 months-9 years). Preoperative revealed regional hypovascularity in the cerebral hemisphere in 5 cases (62%). In 6 patients the cerebral blood flow normalized or increased after craniofacial reconstruction. We demonstrated the presence of ...

1998-09-01

41

Methodological study of hemodynamic analysis of lung mass by contrast enhanced dynamic CT  

Energy Technology Data Exchange (ETDEWEB)

We investigated a method of analyzing the hemodynamics of the lung mass by contrast enhanced dynamic computed tomography (dynamic CT) to determine the difference in vascular supply between the pulmonary artery and bronchial artery using an experimental model. Our experimental model consisted of two injectors connected to two tubes, representing the pulmonary artery and bronchial artery, which were further connected to a chamber representing the lung mass. Following infusion of contrast medium into each tube with some delay time, dynamic CT scans were performed to obtain time density curves of the two tubes and the chamber. Using the time-density curve of contrast passage, flow rates from the two tubes into the chamber were calculated by the curve fitting method. Calculated values correlated well with the adopted flow rates of fluid from the injectors (r=0.893) in the experiment. The results indicate our method of individually measuring ...

1996-06-01

42

Methodological study of hemodynamic analysis of lung mass by contrast enhanced dynamic CT  

International Nuclear Information System (INIS)

We investigated a method of analyzing the hemodynamics of the lung mass by contrast enhanced dynamic computed tomography (dynamic CT) to determine the difference in vascular supply between the pulmonary artery and bronchial artery using an experimental model. Our experimental model consisted of two injectors connected to two tubes, representing the pulmonary artery and bronchial artery, which were further connected to a chamber representing the lung mass. Following infusion of contrast medium into each tube with some delay time, dynamic CT scans were performed to obtain time density curves of the two tubes and the chamber. Using the time-density curve of contrast passage, flow rates from the two tubes into the chamber were calculated by the curve fitting method. Calculated values correlated well with the adopted flow rates of fluid from the injectors (r=0.893) in the experiment. The results indicate our method of individually measuring ...

43

Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism  

British Library Electronic Table of Contents (United Kingdom)

Translating experimental findings into clinically effective therapies is one of the major bottlenecks of modern medicine. As this has been particularly true for cerebrovascular research, attention has turned to the quality and validity of experimental cerebrovascular studies. We set out to assess the study design, statistical analyses, and reporting of cerebrovascular research. We assessed all original articles published in the Journal of Cerebral Blood Flow and Metabolism during the year 2008 against a checklist designed to capture the key attributes relating to study design, statistical analyses, and reporting. A total of 156 original publications were included (animal, in vitro, human). Few studies reported a primary research hypothesis, statement of purpose, or measures to safeguard in...

2011-01-01

44

Synthesis of C-11 iodoantipyrine for positron emission tomography  

Energy Technology Data Exchange (ETDEWEB)

We have developed a method for the synthesis of C-11 iodoantipyrine. Carbon-11-labeled methyl iodide, prepared from /sup 11/CO2, was used to methylate 3-methyl-1-phenyl-2-pyrazolin-5-one to form C-11 antipyrine. Following silica-gel column chromatography and iodination, radiochemical purity of the C-11 iodoantipyrine was more than 99.5%, with a 10% yield and a specific activity of 30 mCi/mumol. Preliminary animal studies showed complete cerebral extraction and local cerebral blood-flow values that were within 4.6% of those obtained using C-14 iodoantipyrine. The C-11 analog, with positron emission tomography, will facilitate local cerebral blood-flow studies in human subjects.

1981-06-01

45

Parametric study of pulsed thermal bumps in supersonic boundary layer  

British Library Electronic Table of Contents (United Kingdom)

A three-dimensional numerical study is performed to explore the effect of pulsed spanwise-periodic surface thermal perturbation (also denoted as thermal bump) in a Mach 1.5 flat plate laminar boundary layer. A high-resolution upwind-biased Roe method is used with the compressive Van Leer harmonic limiter on a suitably refined mesh. The dependence of flow stability characteristics on the variation of thermal bump geometry (shape and dimension) and pulsing properties (disturbance amplitude and frequency) is assessed. It is shown that the finite-span thermal bumps generate streamwise vortices. When the thermal bump is pulsed, vortex shedding is observed, and the streamwise vorticity grows with the downstream distance. Analysis of the integrated disturbance energy indicates that the streamwise...

2011-01-01

46

Harmonic decomposition of orbit data for multipole analysis  

Energy Technology Data Exchange (ETDEWEB)

This paper describes a simple analysis procedure that transforms a set of beamline orbit data into a set of harmonic orbits of first, second, and third order or higher. Each harmonic orbit can be studied individually to identify errors of the specific order with minimum interference from other orders. Effectively these are orbits caused by kicks, due to harmonic errors, propagated through linear lattice. Examples from accelerator study will be presented. The application and inherent limitations of this analysis procedure are discussed.

2005-05-01

47

Comparison of fluid-dynamic modeling of flow with velocity-encoded MR imaging  

International Nuclear Information System (INIS)

This paper develops a fluid dynamic model using finite difference methods characterizing flow in phantoms simulating in vivo conditions and to compare those results with velocity encoded MR images. The phantom consisted of 1-inch (2.5-cm) tubing with semicircular insert and fluid with viscosity, T1, and T2 comparable to blood. Numeric solutions to Navier-Stokes equations for this system were obtained using finite difference methods, with velocity input function of zero at walls and parabolic at both ends. In resulting color raster (CR) images, color temperature represented velocity value. In velocity-encoded MR images acquired under the same flow conditions, phase is proportional to average velocity during application of flow-encoding gradients. Because these gradients are applied along one direction per acquisition, magnitude and direction of velocity are obtained.

1990-11-25

48

Third harmonic lasing in a storage ring free-electron laser  

International Nuclear Information System (INIS)

We report the first experimental achievement of a storage ring free-electron laser (FEL) oscillation on the third harmonic in the near-infrared region. The FEL gain was evaluated as 0.029% per mA. The measured linewidth of the third-harmonic FEL was less than that of the fundamental FEL, and the measured pulse width of the third-harmonic FEL was wider than that of the fundamental FEL. A higher-harmonic FEL should be developed not only to enhance the wavelength region of the FEL but also to vary the characteristics of an FEL micropulse. (author)

2010-09-01

49

Evaluation of the hemodynamics of the femoral head compared with the ilium, femoral neck and femoral intertrochanteric region in healthy adults. Measurement with positron emission tomography (PET)  

International Nuclear Information System (INIS)

Non-traumatic osteonecrosis of the femoral head (ONF) is considered to be a disease that occurs primarily due to ischemia of the femoral head, while its etiology and pathology are not fully understood. It is therefore necessary to identify the characteristics of the hemodynamics of the femoral head. In this study, the hemodynamics in the ilium and proximal regions of the femur, including the femoral head, was investigated using positron emission tomography (PET). The subjects of this study consisted of 8 hip joints of four healthy male adults and 3 hip joints on the contralateral side of a femoral neck fracture, avulsion fracture of the greater trochanter and coxarthrosis (1 case each, all females) for a total of 11 hip joints of 7 subjects. The ages of the subjects ranged from 25 to 87 years (average age: 54 years). Blood flow was measured by means of the H_2"1"5O dynamic study method and blood volume was measured by means ...

2005-10-01

50

True aneurysm originating from the costocervical trunk: surgical excision for recurrence after successful proximal coil embolization.  

Science.gov (United States)

A rare, true aneurysm of a branch of the right subclavian artery is described. Transcatheter coil embolization of the feeder artery was successful in obliterating blood flow into the aneurysm and the mass reduced in size. However, the aneurysm reenlarged over the next week of follow-up due to development and enlargement of the collateral vascular network. Extirpation of the aneurysm was performed. Histopathological examination revealed a true aneurysm. PMID:11833847

2002-01-01

51

Boron in nuclear medicine: New synthetic approaches to PET and SPECT. Final report, May 1, 1986--April 30, 1996  

Energy Technology Data Exchange (ETDEWEB)

Research is described in the development of organometallic reagents in which the boron was attached to a nonreactive organic or inorganic matrix such as polystyrene, silica, or alumina. We developed the synthesis of oxygen-15 labelled butanol, which has been found to be a valuable blood flow agent in humans. We have also developed a series of polymeric borane derivatives which were used to prepare nitrogen-13 labelled amines.

1997-08-01

52

Atlas of nuclear medicine imaging  

Energy Technology Data Exchange (ETDEWEB)

An exhaustive compendium of normal and abnormal imaging is presented. The following systems and procedures are illustrated by over 2800 captioned illustrations: liver, spleen, and hepatobiliary imaging; perfusion and ventilation lung imaging; thyroid imaging; salivary gland imaging; bone imaging; brain imaging; radionuclide cisternography; blood flow studies; gallium imaging; nuclear cardiology; and renal imaging. Not included in the atlas are adrenal imaging procedures and emission computed tomography. (ERB)

1981-01-01

53

Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients  

UK PubMed Central (United Kingdom)

Anemia commonly affects critically ill patients. The causes are multifactorial and include acute blood loss, blood loss from diagnostic testing and blunted red blood cell production. Blood transfusions...Full Text Available

2008-01-01

54

CO_2 reactivity and heterogeneity of cerebral blood flow in ischemic, border zone, and normal cortex  

International Nuclear Information System (INIS)

Regional arterial CO2 tension (PaCO2) reactivity of cerebral blood flow (CBF) and the effect of PaCO2 on the spatial and temporal heterogeneity of CBF were investigated by using autoradiographically determined CBF in the rat middle cerebral artery occlusion model after a 2-h period under pentobarbital anesthesia to clarify the relation between PaCO2 reactivity, CBF heterogeneity, and the temporal cycling of CBF. PaCO2 was adjusted to one of four levels. CBF was determined in four cortical areas and white matter using the tissue fractionation of [14C]iodoantipyrine [( 14C]IAP) in combination with vessel mapping using in vivo 4% thioflavine S. Specific PaCO2 reactivity and CBF were normal in the nonischemic cortex, normal, although slightly depressed, in the border zone far from the ischemic core area, and depressed in the border zone adjacent to the ischemic core area (P less than 0.001) and the ischemic core (P less than 0.001). In normocapnic ...

55

Assessment of liver circulation by quantitative scintiangiography: Evaluation of the relative contribution of the hepatic arterial and portal venous blood flows to liver perfusion  

Energy Technology Data Exchange (ETDEWEB)

Quantitative hepatic scintiangiography was previously used for evaluating the relative contribution of hepatic arterial and portal venous blood flows to the hepatic circulation. The present study compares 3 different procedures (automatic and manual integration, and slope fitting methods) for analyzing the hepatic time activity curves obtained after bolus i.v. injection of 370 MBq /sup 99m/Tc-diethylentriaminopentacetic acid. Twenty five subjects were studied: Five controls, ten cirrhotics, and ten portal hypertensive patients previously submitted to side to side portacaval anastomosis. The correspondence between results given by the different methods was satisfactory only in shunted patients, and the reproducibility of computed parameters was quite poor for all procedures. Accordingly, none of the methods can be considered as supporting reliable quantitative pathophysiological evaluations. However, the hepatic arterial/portal venous ...

1989-04-01

56

Pioglitazone does not affect vascular or inflammatory responses after endotoxemia in humans.  

Science.gov (United States)

PPARgamma agonists have been proposed to exert more than metabolic benefits, particularly by anti-inflammatory mechanisms. We hypothesized that pioglitazone might modulate inflammatory and vascular responses to lipopolysaccharide (LPS). In a placebo-controlled parallel-group study in 18 healthy male subjects, the E. coli endotoxin model of inflammation (20 IU/kg i. v.) was employed to test the effect of 60 mg pioglitazone over nine days on inflammatory cytokines. Macrovascular function and microvascular blood flow were assessed by brachial artery ultrasound and retinal blood flow parameters, respectively. Pioglitazone increased brachial artery diameter by 5.6% but had no effect on other outcome parameters under resting conditions. LPS increased cytokine levels to peak concentrations of 91.3+/-22.5 ng/ml (IL-6), 261.4+/-60.0 ng/ml (TNFalpha), and 524.5+/-15.3 ng/ml (VCAM-1). The endotoxin caused ...

2008-05-21

57

2D modeling and preliminary in vitro investigation of a prototype high gradient magnetic separator for biomedical applications.  

Science.gov (United States)

High gradient magnetic separation (HGMS) of magnetic materials from fluids or waste products has many established industrial applications. However, there is currently no technology employing HGMS for ex-vivo biomedical applications, such as for the removal of magnetic drug- or toxin-loaded spheres from the human blood stream. Importantly, human HGMS applications require special design modifications as, in contrast to conventional use where magnetic elements are permanently imbedded within the separation chambers, medical separators need to avoid direct contact between the magnetic materials and blood to reduce the risk of blood clotting and to facilitate convenient and safe treatment access for many individuals. We describe and investigate the performance of a magnetic separator prototype designed for biomedical applications. First, the capture efficiency of a prototype HGMS separator unit consisting of a short tubing ...

2007-03-30

58

Global suppression of mitogen-activated ovine peripheral blood mononuclear cells by surface protein activity from Mycoplasma ovipneumoniae  

British Library Electronic Table of Contents (United Kingdom)

Mycoplasma ovipneumoniae is associated with chronic non-progressive pneumonia of sheep and goats. As with many other mycoplasmas involved in animal diseases, protective immune responses have not been achieved with vaccines, even though antibody responses can be obtained. This study focuses on characterizing the interaction of M. ovipneumoniae with ovine PBMC using carboxy-fluorescein-succinimidyl-ester (CFSE) loading and flow cytometry to measure lymphoid cell division. M. ovipneumoniae induced a strong in vitro polyclonal suppression of CD4^+, CD8^+, and B blood lymphocyte subsets. The suppressive activity could be destroyed by heating to 60^oC, and partially impaired by formalin and binary ethyleneimine treatment that abolished its viability. The activity resided on the surface-exposed m...

2010-01-01

59

Striatal dysfunction in attention deficit and hyperkinetic disorder  

Energy Technology Data Exchange (ETDEWEB)

We have previously reported that periventricular structures are hypoperfused in attention deficit and hyperactivity disorder (ADHD). This study has expanded the number of patients, who were divided into two groups: six patients with pure ADHD, and 13 patients with ADHD in combination with other neurologic symptoms. By using xenon 133 inhalation and emission tomography, the regional cerebral blood flow distribution was determined and compared with a control group. Striatal regions were found to be hypoperfused and, by inference, hypofunctional in both groups. This hypoperfusion was statistically significant in the right striatum in ADHD, and in both striatal regions in ADHD with other neuropsychologic and neurologic symptoms. The primary sensory and sensorimotor cortical regions were highly perfused. Methylphenidate increased flow to striatal and posterior periventricular regions, and tended to decrease ...

1989-01-01

60

Random walk function in the analysis of time-activity curves from dynamic radionuclide studies  

Energy Technology Data Exchange (ETDEWEB)

The random walk function is a mathematical function derived from studies of the mass transport and flow of diffusible materials through tubes. Approximations to the function were first used some time ago in the field of cardiac tracer dilution curves, but in the absence of rapid and reproducible curve fitting the method never became commonplace. The current study uses the latest curve-fitting techniques and shows how the method may be used with precision in the analysis of time-activity curves from dynamic oesophageal and blood flow studies. The physiological basis of the method is given and parameters obtained which relate to both the rate of flow and the local dispersion of the bolus.

1987-04-01

61

Nonlinear response of superconductors to alternating fields and currents  

Science.gov (United States)

This report discusses the following topics on superconductivity: nonlinearities in hard superconductors such as surface impedance of a type II superconductimg half space and harmonic generation and intermodulation due to alternating transport currents; and nonlinearities in superconducting weak links such as harmonic generation by a long Josephson Junction in a superconducting slab.

1997-10-08

62

Optimum plasma conditions for the efficient high-order harmonic generation in platinum plasma  

International Nuclear Information System (INIS)

We studied the optimum plasma conditions that are required for efficient high-order harmonic generation in platinum plume. Harmonics up to the 49th order (?=16.32 nm) are analyzed under various conditions of laser-plasma interaction. Time-resolved ultraviolet spectra of platinum plasma at both optimum and nonoptimum conditions of harmonic generation are presented. We calculated the ionization states of the plasma, free electron density, and singly charged ion density at different prepulse intensities and compared them with experimental results.

2007-06-01

63

Operating Manual for Single-Shot Autocorrelator  

Science.gov (United States)

... pulses by a 50/50 beamsplitter and recombined in space and in time inside a wafer of KDP crystal which generates a second harmonic of the ...

1993-01-01

65

INTERACTIONS OF COHERENT OPTICAL RADIATION WITH ...  

Science.gov (United States)

... and flashtube. Unfortunately, we had insufficient laser intensity to use the harmonic from a KDP crystal as a monitor. This ...

1964-08-31

67

Lupus  

Medline Plus

... diagnosed. A complete blood count (CBC), urinalysis, blood chemistries, and erythrocyte sedimentation rate (ESR) tests can provide ...

68

Spherical harmonic operator method of solving the transport equation in curvilinear coordinates. Application to #gamma#-theta geometry  

International Nuclear Information System (INIS)

An explicite PN solution of the multi-dimensional homogeneous neutron transport equation is given by expanding the angular flux into a series of geometry-independent spherical harmonics operators. An algorithm is developed for representing the spherical harmonic operators in orthogonal curvilinear coordinates. The general formulae are applied to two-dimensional spherical geometry; detailed P3 formulae are given. (orig.).

69

Second harmonic generation of copper-vapor pulsed laser radiation  

Energy Technology Data Exchange (ETDEWEB)

An experimental study of second harmonic generation in a copper-vapor pulsed laser with an ADP crystal is presented. The ratio of the conversion into the second harmonic is found to depend on the average power of the exciting radiation. The maximum conversion ratio was 8.5%. Thermal self-defocusing is the main obstacle to obtaining high average powers at the double frequency.

1980-08-01

70

Localisation of the neuropeptide PACAP and its receptors in the rat parathyroid and thyroid glands.  

Science.gov (United States)

PACAP (pituitary adenylate cyclase activating polypeptide) is widely distributed neuropeptide acting via three subtypes of receptors, PAC(1), VPAC(1) and VPAC(2). Here we examined the localisation and nature of PACAP-immunoreactive nerves in the rat thyroid and parathyroid glands and defined the distribution of PAC(1), VPAC(1) and VPAC(2) receptor mRNA's. In the parathyroid gland a large number of nerve fibres displaying PACAP-immunoreactivity were distributed beneath the capsule, around blood vessels and close to glandular cells. Most of the PACAP-nerves were sensory, since they co-stored CGRP (calcitonin-gene-related peptide) and were sensitive to capsaicin-treatment. mRNA's for PAC(1) and VPAC(2) receptors occurred in the parathyroid gland, mainly located in the glandular cells. In the thyroid gland PACAP-immunoreactive nerve fibres were associated with blood vessels, thyroid follicles and parafollicular C-cells. A high degree of ...

2010-12-19

71

Simultaneous assessment of left ventricular function from gated myocardial perfusion SPECT. Utility of QGS (Quantitative Gated SPECT) program  

International Nuclear Information System (INIS)

Quantitative gated SPECT (QGS) was evaluated in 7 normal volunteers and 31 patients with cardiac diseases. Adequate cut off value of a prefilter was 0.45. In phantom, the left ventricular volume value was 93.9% of determined value by 180-degree projection in L type and 98.8% by 360-degree projection in opposed type. In normal volunteers, LVEF measured by QGS program related to value by first pass method. As for functional map, regional EF and wall motion decreased at the septum side, and wall thickening at base side of heart. Good correlation was recognized (p<0.0001) between blood flow image and functional map (regional EF and wall thickening). In 20 cases of acute myocardial infarction, lesion was detected conspicuously in regional EF and wall motion. The accuracy of coronary arterial stenosis improved in functional map (regional EF 92%, wall motion 92% and wall thickening 88%). In particular, the accuracy of 3 rami lesion was 100% in ...

1998-08-01

72

Measurement of local cerebral blood flow by computerized tomography with inhalation of stable xenon and curve-fitting method  

Energy Technology Data Exchange (ETDEWEB)

Non-invasive methods are described for estimating local cerebal blood flows (LCBF) and local partition coefficients (Llambda) during inhalation of 30 % stable xenon gas (Xe) in oxygen during CT scanning. After the denitrogenation with pure oxygen breathing, 30 % Xe is inhaled for four minutes to minimize subanesthetic effects with a rubber facemask and the delivery system of Xe. Local time-..delta.. Hounsfield units curve during the Xe wash-in and wash-out phase is utilized in order to calculate Llambda and LCBF using a least squares curve fitting analysis. Calculated Llambda and LCBF with the new method manifested reasonable distribution between the grey and white matters, and reproducibility was excellent in our study. Several case studies of patients with cerebral infarction are presented to demonstrate the characterization of Llambda and LCBF patterns in various tissues and theoretical grounds underlying the new method of curve fitting ...

1988-07-01

73

Measurement of local cerebral blood flow by computerized tomography with inhalation of stable xenon and curve-fitting method  

International Nuclear Information System (INIS)

Non-invasive methods are described for estimating local cerebal blood flows (LCBF) and local partition coefficients (L#lambda#) during inhalation of 30 % stable xenon gas (Xe) in oxygen during CT scanning. After the denitrogenation with pure oxygen breathing, 30 % Xe is inhaled for four minutes to minimize subanesthetic effects with a rubber facemask and the delivery system of Xe. Local time-#DELTA# Hounsfield units curve during the Xe wash-in and wash-out phase is utilized in order to calculate L#lambda# and LCBF using a least squares curve fitting analysis. Calculated L#lambda# and LCBF with the new method manifested reasonable distribution between the grey and white matters, and reproducibility was excellent in our study. Several case studies of patients with cerebral infarction are presented to demonstrate the characterization of L#lambda# and LCBF patterns in various tissues and theoretical grounds underlying the new method of curve ...

74

FY1999 Meeting of The Society of Heating, Air-Conditioning and Sanitary Engineering of Japan. Thermal simulation I; 1999 nendo gakujutsu koenkai gaiyo. Onnetsu simulation 1  

Energy Technology Data Exchange (ETDEWEB)

E-35 reported the specific air flow analysis program using a CFSV model (including a human body model) to develop a high-accuracy evaluation simulator for heterogeneous thermal environment based on human thermal physiological conditions. E-36 reported development of the radiation heat transfer analysis module by using a numerical integral method to calculate shape factors. Radiation heat transfer characteristics every body part were clarified quantitatively by this module. E-37 reported the results on continuous measurement of physiological conditions and thermal environment factors every monitor under controlled indoor thermal environment, to collect measurement data necessary for improving the accuracy of a prediction program for human body temperatures. E-38 reported the study result on physiological reaction and subjective evaluation through an examinee experiment in a blood controlled region, to collect basic data for the above ...

1999-12-05

75

Cognitive performance correlates with cerebrovascular impairments in multi-infarct dementia  

International Nuclear Information System (INIS)

Cerebral blood flow (CBF) was measured by the "1"3"3Xe inhalation method in patients with multi-infarct dementia (MID, N = 26), Alzheimer's dementia (AD, N = 19), and among age-matched, neurologically normal, healthy volunteers (N = 26). Cognitive performance was assessed in all subjects using the Cognitive Capacity Screening Examination (CCSE). Cerebral vasomotor responses were calculated from differences in values of mean hemispheric gray matter blood flow (Delta CBF) measured during inhalation of 100% oxygen (hyperoxia) compared with CBF measured while breathing room air. Significant correlations were found between CCSE performance and vasomotor responsiveness in patients with MID (P less than .01), but not in patients with AD or in neurologically normal volunteers. Loss of vasomotor responsiveness is an indicator of cerebrovascular disease with rigidity and/or loss of reactivity of cerebral vessels, ...

76

Application of a beta microprobe for quantification of regional cerebral blood flow with {sup 15}O-water and PET in rhesus monkeys  

Energy Technology Data Exchange (ETDEWEB)

A beta microprobe was successfully applied to monitor arterial input function for quantification of regional cerebral blood flow (rCBF) in the monkey brain with {sup 15}O-water and positron emission tomography (PET). The sensitivity of the probe was approximately 0.83 to 1.67 cps/kBq/ml depending on the studies. A preliminary study was performed to find a suitable use and to evaluate the performance of the system and data analysis procedure. The results showed that dispersion correction of measured input function was unnecessary if microprobes were connected directly to the arterial catheter. Then multiple CBF measurements were done in three monkeys under anesthesia. Identical regions of interest were placed with the aid of magnetic resonance imaging (MRI) of each monkey and rCBF values were estimated. Estimated rCBFs were reproducible for several measurements. The mean CBF value for a pentobarbital anesthetized monkey was 46.0 ml/min/100 g ...

1998-02-01

77

A comparison with result of normalized image to different template image on statistical parametric mapping of ADHD children patients  

Energy Technology Data Exchange (ETDEWEB)

We studied 64 ADHD children patients group (4 {approx} 15 ys, mean age: 8 {+-} 2.6 ys. M/F: 52/12) and 12 normal group (6 {approx} 7 ys, mean age: 9.4 {+-} 3.4 ys, M/F: 8/4) of the brain had been used to analysis of blood flow between normal and ADHD group. For analysis of Children ADHD, we used 12 children's mean brain images and made Template image of SPM99 program. In crease of blood flow (P-value 0.05), the result of normalized images to Template image to offer from SPM99 program, showed significant cluster in inter-Hemispheric and occipital Lobe, in the case of normalized images to children template image, showed inter-hemispheric and parietal lobe.

2003-06-15

78

Visualization of right atrial appendix by Thallium-201 myocardial scintigraphy: concise communication  

Energy Technology Data Exchange (ETDEWEB)

The atrial myocardium has been barely visible with thallium-201 myocardial scintigraphy. This is probably related to the difference in size, distance from anterior chest wall, and small coronary blood flow of the atrium, compared with the ventricle. We have encountered eight cases of visualization of the right atrial appendix (RAA). The RAA was identified from multiple projections in all cases and sometimes confirmed by radionuclide angiocardiography. Evidence derived from ECG, chest radiographs, and cardiac catheterization, indicated that the most important factor in the visualization might be the displacement of the RAA to a more anterior position.

1980-10-01

79

PET/CT cardiology: an area whose boundaries are still out of sight  

International Nuclear Information System (INIS)

Positron emission tomography (PET) and X-ray computed tomography (CT) performed with PET/CT cameras allow us to obtain concurrently information on the presence and degree of alterations of myocardial perfusion and metabolism and on coronary arteries calcification. Furthermore, by gated myocardial perfusion studies, PET may provide crucial information on regional coronary blood flow reserve and endothelial dysfunction. A number of recent papers provide some insight on the potential of PET/CT in cardiology and in the assessment of various cardiovascular diseases including various types of vasculitis and metabolic diseases.

2006-05-01

80

Pseudospin symmetry and the relativistic harmonic oscillator  

CERN Document Server

A generalized relativistic harmonic oscillator for spin 1/2 particles is studied. The Dirac Hamiltonian contains a scalar, $S$, and a vector, $V$, quadratic potentials in the radial coordinate, as well as a tensor potential, $U$, linear in $r$. Setting either or both combinations $\\Sigma=S+V$ and $% \\Delta=V-S$ to zero, analytical solutions for bound states of the corresponding Dirac equations are found. The eigenenergies and wave functions are presented and particular cases are discussed, devoting a special attention to the non-relativistic limit and the case $\\Sigma=0$, for which pseudospin symmetry is exact. We also show that the case $U=\\Delta=0$ is the most natural generalization of the non-relativistic harmonic oscillator. The radial node structure of the Dirac spinor is studied for several combinations of harmonic oscillator potentials, and that study allows us to explain why nuclear intruder levels cannot be ...

2004-01-01

81

On the Approach to Spherical Harmonics by Maxwell, Thomson and Tait  

CERN Document Server

We present a unified self-consistent review of the approach to spherical harmonics developed in the second half of the 19th century by Maxwell and by Thomson and Tait. We remark how this spherical coordinate-free approach straightforwardly leads to physically very important results of the theory of solid and surface harmonics which become rather tedious to work out when using spherical coordinates and associated Legendre functions. These results include, among others, the addition theorem, spherical wave expansions, the construction of the standard set of normalized spherical harmonics, Y_lm - together with their rotational properties-, and recursion relations. We provide new proofs for Maxwell's theorem, the addition theorem and Hobson's theorem, respectively, using in the latter some elementary notions of the symbolic techniques proper of the theory of invariants. Also, we give an approach based on compact vector methods ...

2008-01-01

82

Regional spinal cord blood flow during local cooling  

Energy Technology Data Exchange (ETDEWEB)

We used the tissue distribution of ({sup 14}C)butanol to quantitate regional blood flow in the spinal cord (RSCBF) of pentobarbital-anesthetized, normothermic rats in which segmental local cooling pentobarbital-anesthetized, normothermic rats in which segmental local cooling of the spinal cord (to 25-28{degrees}C) at vertebral levels C4-C6 (n = 6) or T13-L1 (n = 6) was induced. Thirty minutes later, blood flow measurements were made at seven levels of the spinal cord and in the sciatic nerve trunks and biceps femoris muscles. Sham-cooled rats served as controls (n = 12). In control rats, RSCBF varied between 41.5 +/- 2.4 and 65.1 +/- 3.2 ml.min-1.100 g-1. Local cooling of the C4-C6 cord segment reduced RSCBF by 32%, from 65.1 +/- 3.2 to 44.4 +/- 3.5 ml.min-1.100 g-1 (P less than 0.01). Tissue vascular resistance (R) in the cooled C4-C6 segment was elevated versus control. There were no other changes in ...

1990-06-01

83

Magnetic resonance imaging of chronic aortic dissection  

International Nuclear Information System (INIS)

17 patients with chronic aortic dissection were examined by MRI. In 12 patients, comparison between gradient echo sequences and SE sequences was possible. Gradient echo sequences, unlike SE sequences, permitted evaluation of flow in the true and false lumen, reliable differentiation between thrombus and flowing blood and clear delination of the intimal flap. An additional comparison between transoesophageal ultrasound and MRT in 15 patients showed significant advantages in favour of MRI. In three patients MRI was able to detect more proximal origins of the dissection. Moreover, MRI allowed evaluation of the major aortic branches and their relation to the dissection; this was not possible with ultrasound. MRI plays an important role in the follow-up of chronic aortic dissections. (orig.).

84

Harmonics in power systems of ships with electrical propulsion drives. Comparison between different converters  

Energy Technology Data Exchange (ETDEWEB)

In this report the effects of harmonics in marine power systems is discussed and a comparison is given between the most typical converter types, including pulse width modulated drives, load commutated inverters and cycloconverters. The effect of harmonic distortion on the power system equipment and loads is first briefly discussed. Special attention is given to the circumstances in the low voltage distribution system, where general load equipment is connected. In addition to the total harmonic distortion the effect of voltage deviation to the supply quality is also considered. The origin of harmonics in the load currents of the three converter types is then considered. The differences between the converters are outlined, and the most typical spectra are presented. The possible means for reducing the harmonic distortion are also studied. The solutions considered are the increasing of ...

1996-11-01

85

Non-thermal atmospheric pressure HF plasma source: generation of nitric oxide and ozone for bio-medical applications  

International Nuclear Information System (INIS)

A new miniature high-frequency (HF) plasma source intended for bio-medical applications is studied using nitrogen/oxygen mixture at atmospheric pressure. This plasma source can be used as an element of a plasma source array for applications in dermatology and surgery. Nitric oxide and ozone which are produced in this plasma source are well-known agents for proliferation of the cells, inhalation therapy for newborn infants, disinfection of wounds and blood ozonation. Using optical emission spectroscopy, microphotography and numerical simulation, the gas temperature in the active plasma region and plasma parameters (electron density and electron distribution function) are determined for varied nitrogen/oxygen flows. The influence of the gas flows on the plasma conditions is studied. Ozone and nitric oxide concentrations in the effluent of the plasma source are measured using absorption spectroscopy and electro-chemical ...

2010-01-01

86

Hypercapnic normalization of BOLD fMRI: comparison across field strengths and pulse sequences.  

DEFF Research Database (Denmark)

The blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) signal response to neural stimulation is influenced by many factors that are unrelated to the stimulus. These factors are physiological, such as the resting venous cerebral blood volume (CBV(v)) and vessel size, as well as experimental, such as pulse sequence and static magnetic field strength (B(0)). Thus, it is difficult to compare task-induced fMRI signals across subjects, field strengths, and pulse sequences. This problem can be overcome by normalizing the neural activity-induced BOLD fMRI response by a global hypercapnia-induced BOLD signal. To demonstrate the effectiveness of the BOLD normalization approach, gradient-echo BOLD fMRI at 1.5, 4, and 7 T and spin-echo BOLD fMRI at 4 T were performed in human subjects. For neural stimulation, subjects performed sequential finger movements at 2 Hz, while for global stimulation, subjects breathed a 5% CO(2) ...

2004-01-01

90

Intensification of Harmonic Spontaneous Radiation with a Novel Undulator  

Science.gov (United States)

We have calculated the on-axis spectrum of spontaneous radiation emitted by an electron moving along a planar undulator that has a magnetic profile along the axis that approximates a square wave. (This could be obtained in practice by driving a ferromagnetic undulator into saturation by excessive current in the windings.) We find considerable enhancement of the harmonic radiation spectrum. We compare the harmonic power emitted by an electron moving through an undulator having a sine-wave field profile with the radiation emitted from an undulator having a square-wave profile; the latter is approximated by the first three Fourier components of the undulator magnetic field profile along the axial direction. Examples are computed for 40MeV electrons taking K < 1, for spontaneous radiation emitted along the axis of the system. The emission at harmonics f > 1 is greatly enhanced for the approximate square-wave magnetic ...

1998-11-01

91

{sup 99m}Tc-MDP scintigraphy of femoral head necrosis following femoral neck fracture  

Energy Technology Data Exchange (ETDEWEB)

Secondary ischemic necrosis of femoral head due to loss of blood supply following to femoral neck fracture is well known. The regional distribution of bone-seeking radiopharmaceuricals in the skeleton can depend on a number of factors, but bone blood flow is a major physiological determinant of regional skeletal uptake of Tc-99m polyphosphate and bone imaging may thus be used for the evaluation of vascularity of the femoral head. The authors made a comparative study of scintigraphic findings and operative findings of 28 cases of femoral neck fracture treated at Kyung Hee University Hospital from April 1980 to May 1984. The results were as follows: 1. In 16 cases of proven avascular necorsis of femoral head, scintigraphy showed absent or decreased activity in 14 cases (87.5%), while radiography showed increased density in 10 cases (62.5%). 2. In 12 cases of proven vital femoral head, scintigraphy showed increased activity in ...

1985-02-15

92

Urinary tract infection: diabetic women's strategies for prevention.  

Science.gov (United States)

Urinary tract infection (UTI) is a common problem in the female population. Women with diabetes mellitus are possibly at a higher risk. The usual medical therapy for UTI is antibiotic treatment. The aim of this study is to explore strategies employed by diabetic women for prevention and self-treatment of UTI. Forty-two women with diabetes mellitus who had experienced at least one episode of UTI in the last six months were included. Data collection included background information, questions about prevention and self-treatment strategies and a clinical examination to measure maximal urine flow, residual urine, a blood test evaluating diabetic control (HbA1c) and a urine test strip for determination of glucose, leucocytes, nitrite, blood, protein and pH. Thirty-five participants (83.3%) reported changes in daily routines like 'always keeping warm', 'increased fluid intake', 'good personal hygiene' as prevention strategies. ...

93

Opto-acoustic recanilization delivery system  

Energy Technology Data Exchange (ETDEWEB)

Fiber delivered laser pulses emulsify thrombus by mechanical stresses that include a combination of pressure, tension and shear stress. Laser radiation is delivered to the locality of a thrombus and the radiation is absorbed by blood, blood dot, or other present materials. The combination of a leading pressure wave and subsequent vapor bubble cause efficient, emulsification of thrombus. Operating the laser in a low average power mode alleviates potential thermal complications. The laser is operated in a high repetition rate mode to take advantage of ultrasound frequency effects of thrombus dissolution as well as to decrease the total procedure time. Specific parameter ranges for operation are described. The device includes optical fibers surrounding a lumen intended for flow of a cooling agent. The fibers may be arranged concentrically around the lumen to deliver radiation and heat over as large an area as possible. An ...

2002-01-01

94

Using ICCD as a fast optical switch to measure harmonic super-radiation from an optical klystron in a storage ring  

International Nuclear Information System (INIS)

An optical klystron is built in the 800 MeV electron storage ring at University of Science and Technology of China for harmonic super-radiation generation. In single bunch operation mode the repetition rate of the spontaneous radiation pulses is about 4.533 MHz, and the repetition rate of the seed laser pulses is about 3 Hz, while the radiation pulse duration is 300 ps. For measuring harmonic radiation a high on/off ratio ICCD is used as an optical switch to reject spontaneous radiation pulses of high repetition rate

2001-07-01

95

Characteristics of cosmic ray pole-equator anisotropy derived from spherical harmonic analysis of neutron monitor data  

International Nuclear Information System (INIS)

The spherical harmonic analysis of cosmic ray neutron data from the worldwide network neutron monitor stations during the years 1966 to 1969 was carried out. The second zonal harmonic component obtained from the analysis corresponds to the Pole-Equator anisotropy of the cosmic ray neutron intensity. Such an anisotropy makes a semiannual variation. In addition to this, it is shown that the Pole-Equator anisotropy makes a variation depending on the interplanetary magnetic field (IMF) sector polarities around the passages of the IMF sector boundary. A mechanism to interpret these results is also discussed.

1985-08-01

96

Safety in the forefront  

Energy Technology Data Exchange (ETDEWEB)

Safety in general and harmonization of International Maritime Organization rules on mobile offshore drilling rig operation in particular are discussed. The improvement of the industry's safety record is also discussed.

1985-02-01

97

Preliminary representation of world population by spherical harmonics.  

UK PubMed Central (United Kingdom)

The geographical arrangement of people on the surface of the earth is approximated by a mathematical equation of 361 terms. This is a convenient form for comparison with other distributions and for...Full Text Available

1992-07-15

99

Harmonized Tariff Schedule Codes Flagged with Prior Notice ...  

Science.gov (United States)

... 3004505040***, MEDICAMENTS, DOSED, VITAMINS, MULTIPLE, OTHER COMBINATIONS, FD3***. 3104100000**, CARNALLITE, SYLVITE AND OTHER CRUDE POTASSIUM SALTS, FD3**. ...

100

The usefulness of CBF brain SPECT in forensic medicine: the civil law codes cases. A description of four cases  

International Nuclear Information System (INIS)

The aim of this report was to assess the usefulness of cerebral blood flow (CBF) scanning utilising the SPECT technique in forensic medicine cases in the area of civil law cases. CBF SPECT scanning was performed in four patients utilising "9"9"mTc-ECD and a triple-head gammacamera. In the analysis both the asymmetry index and cerebellar normalisation were applied. Reference values were obtained by studying 30 healthy volunteers. In those cases CBF SPECT scanning played an important role in forensic argument. It influenced the sentence and the amount of financial compensation. CBF SPECT scanning may provide valuable information in forensic medicine argument in civil law cases, but only when taken together with psychometric tests and other neuroimaging methods (CT, MRI). The value of CBF SPECT scanning alone may be limited in judicial proceedings. (author)

101

SAR of Cu (II) Thiosemicarbazone Complexes as Hypoxic Imaging Agents: MM3 Analysis and Prediction of Biologic Properties  

British Library Electronic Table of Contents (United Kingdom)

Abstract Copper(II) bis(thiosemicarbazone) are very useful for blood flow and hypoxic imaging. The aim of this study was to identify structure-activity relationships (SARs) within a series of analogues with different substitution patterns in the ligands, in order to design improved hypoxia imaging agents and elucidate hypoxia selectivity mechanisms. Genetic algorithms (GAs) were used to develop specific copper metal-ligand force field parameters for the MM3 force-field calculations. These new parameters produced results in good agreement with experiment and previously reported copper metal-ligand parameters. A successful quantitative SAR (QSAR) for predicting the several classes of Cu(II)-chelating ligands was built using a training set of 21 Cu(II) complexes. The QSAR exhibited a correlat...

2010-01-01

102

Delaying the superficial inferior epigastric artery flap: A solution to the problem of the small calibre of the donor artery  

British Library Electronic Table of Contents (United Kingdom)

Background: Superficial inferior epigastric artery (SIEA) flap has a great advantage over other flaps of the area, that is, readily non-existent donor-site problems. The main reason why the SIEA flap has never been extensively used in breast reconstruction is the small diameter and variable anatomy of its donor artery. This study presents a possibility of enlarging the SIEA diameter using the delay-phenomenon mechanism. Methods: A prospective clinical study of 26 patients was undertaken. Prior to surgery, ultrasound examinations were performed, measuring the diameter of SIEA and the velocity of blood flow in SIEA. The ipsilateral deep inferior epigastric artery (DIEA) was then ligated in all patients who had a measurable SIEA preoperatively. Two weeks later, measurements were repeated. The...

2011-01-01

103

Adalimumab treatment in Crohn's disease does not induce early changes in regulatory T cells  

British Library Electronic Table of Contents (United Kingdom)

Abstract Objective. Anti-TNF-a antibodies has been suggested to modulate regulatory T cell (Treg) percentages in rheumatoid arthritis, but results from studies of Crohn's disease (CD) are conflicting. We investigated dynamic changes of circulating Tregs in CD during treatment with the anti-TNF-a-antibody adalimumab (Humira, Abbott Laboratories A/S, Emdrupvej 28C, DK-2100 Copenhagen). Material and methods. Blood samples from 26 CD patients were analysed using flow cytometry before and 1 and 26 weeks after initiation of adalimumab treatment to determine the percentage of Tregs among CD4++ T cells. Results. In spite of a significant decline in disease activity scores and biochemical markers of inflammation, during the first week of treatment, we did not observe early modulating effects of ada...

2011-01-01

104

Nuclear medicine progress report for quarter ending March 31, 1985  

Energy Technology Data Exchange (ETDEWEB)

Radioiodinated 15-(p-iodophenyl)-3,3-dimethylpentadecanoic acid (DMIPP) has been prepared as a new terminal iodophenyl-substituted fatty acid containing dimethyl-branching at the beta-position. Iodine-125-labeled DMIPP showed rapid, high myocardial uptake (min, mean % injected dose/g) in fasted rats (5, 4.67; 30, 5.06; 60, 4.79; 120, 4.37), and also exhibited high heart:blood ratios (min, ratio) 5, 3:1; 30, 12:1; 60, 12:1; 120, 13:1. These data demonstrate an unanticipated much longer myocardial residence time with DMIPP (+/sub 1/2/ 7-8 h) than observed with either the 3-monomethyl (BMIPP) analogue (+/sub 1/2/ 30-45 min) or the rapidly metabolized straight-chain (IPP) analogue (+/sub 1/2/ 10-15 min). The (/sup 123/I)DMIPP is thus an excellent candidate for clinical evaluation of regional fatty acid metabolism under conditions where the uptake of energy substrates can be assessed independent of regional blood delivery. Studies with the new ...

1985-07-01

105

Shaping pulses using frequency conversion with a modulated picosecond free electron laser  

Energy Technology Data Exchange (ETDEWEB)

Computer simulations and experiments indicate that we can shape the infrared picosecond pulses of the Mark III FEL in amplitude, frequency, and phase. Strongly modulated fundamental and second harmonic pulses have been generated by operating the Mark III FEL in the regime of strong sideband growth. In this paper, we present the results of simulations and experiments for second harmonic generation with fundamental inputs from 2 to 3 {mu}m.

1995-12-31

106

Real time closed orbit correction system  

Energy Technology Data Exchange (ETDEWEB)

We describe a global closed orbit feedback experiment, based upon a real time harmonic analysis of both the orbit movement and the correction magnetic fields. The feedback forces the coefficients of a few harmonics near the betatron tune to vanish, and significantly improves the global orbit stability. We present the results of the experiment in the UV ring using 4 detectors and 4 trims, in which maximum observed displacement was reduced by a factor of between 3 and 4. 4 refs., 3 figs.

1989-01-01

107

Nonlinear effect in vibroseis data; Vibroseis kiroku ni oite mitomerareru hisenkei koka  

Energy Technology Data Exchange (ETDEWEB)

This paper describes nonlinear effect recognized in Vibroseis data. Harmonics is a wave of frequency in integer factors generated in association with basic sweep vibrated by Vibroseis. Harmonics is generated because vibration in the vicinity of seismic source contains nonlinear terms. Seismic exploration using the reflection method often discusses propagation of seismic waves hypothesized as a linear phenomenon. Vibroseis data analysis, however, requires evaluation of the effect of the harmonics on accuracy. Vibroseis investigation measures may be taken by eliminating n-order harmonics by using the phase control method, and generating seismic source sweep in which the phase is shifted by 180/(n-1) each time in order to leave the basic sweep. Methods to increase the sweep length include a method to expel strain to a location outside the range of the subject travel time. Up-sweep (a sweep changing from ...

1997-05-27

108

Intensification of harmonic spontaneous radiation with a novel undulator  

International Nuclear Information System (INIS)

We have calculated the on-axis spectrum of spontaneous radiation emitted by an electron moving along a planar undulator that has a magnetic profile along the axis that approximates a square wave. (This could be obtained in practice by driving a ferromagnetic undulator into saturation by excessivecurrent in the windings.) We find considerable enhancement of the harmonic radiation spectrum. We compare the harmonic power emitted by an electron moving through an undulator having a sine-wave field profile with the radiation emitted from an undulator having a square-wave profile; the latter is approximated by the first three Fourier components of the undulator magnetic field profile along the axial direction. Examples are computed for 40MeV electrons taking K1 is greatly enhanced for the approximate square-wave magnetic profile: the ratio of the power emitted at f=5 by the square-wave undulator to that of the sine-wave undulator is about 15 (whereas ...

1999-07-01

109

Effects of clove (Caryophyllus aromaticus L.) on the labeling of blood constituents with technetium-99m and on the morphology of red blood cells  

Energy Technology Data Exchange (ETDEWEB)

Clove (Caryophyllus aromaticus L.) has been used for clinical procedures. Blood constituents labeled with technetium-99m (99mTc) are used in nuclear medicine. The aim of this work was to evaluate the effects of clove extract on the labeling blood constituents with 99mTc and on the morphology of red blood cells. Blood samples were incubated with clove, stannous chloride and 99mTc. Plasma, blood cells, insoluble fractions of plasma and blood cells were separated. The radioactivity was counted and percentage of radioactivity (%ATI) to each blood fraction was calculated. The shape and morphometric parameter (perimeter/area ratio) were evaluated. Clove extract altered significantly (p<0.05) the %ATI of blood constituents and the shape of red blood cells without modifying the perimeter/area ratio. ...

2007-09-15

110

Check-Up America: Know Your Risk, Lower Your Risk for Diabetes and Heart Disease  

Medline Plus

... Cholesterol High Blood Glucose High Blood Pressure Overweight Physical Activity Small Steps for Your Health Smoking Age, ... blood pressure, unhealthy cholesterol, and high blood glucose. Physical Activity Staying active helps manage your blood glucose, ...

111

The effect of EC-IC bypass surgery on resting cerebral blood flow and cerebrovascular reserve capacity studied with stable Xe-CT and acetazolamide test  

International Nuclear Information System (INIS)

Cerebral blood flow (CBF) and cerebrovascular reserve capacity (CRC) were measured by stable xenon computerized tomography (Xe-CT) and acetazolamide test in 15 patients with cerebrovascular disease before and after extracranial-intracranial (EC-IC) bypass surgery for minor stroke, reversible ischemic neurological deficit or transient ischemic attack. All had angiographically shown occlusive lesions of the major arterial trunk. In the present series, global analysis showed that the bypass did not increase the resting rCBF, but did increase the rCRC. We divided the patients into four groups according to the preoperative resting rCBF and rCRC. All 3 patients with normal resting rCBF and reduced rCRC showed postoperative improvement of rCRC. Of 6 patients with reduced CBF and reduced CRC, three had postoperative increase in resting CBF and four had increased CRC. One of two patients with reduced CBF and normal CRC showed only an increase in CRC. We ...

112

Intestinal circulation during inhalation anesthesia  

Energy Technology Data Exchange (ETDEWEB)

This study was designed to evaluate the influence of inhalational agents on the intestinal circulation in an isolated loop preparation. Sixty dogs were studied, using three intestinal segments from each dog. Selected intestinal segments were pumped with aortic blood at a constant pressure of 100 mmHg. A mixture of /sub 86/Rb and 9-microns spheres labeled with /sup 141/Ce was injected into the arterial cannula supplying the intestinal loop, while mesenteric venous blood was collected for activity counting. A very strong and significant correlation was found between rubidium clearance and microsphere entrapment (r = 0.97, P less than 0.0001). Nitrous oxide anesthesia was accompanied by a higher vascular resistance (VR), lower flow (F), rubidium clearance (Cl-Rb), and microspheres entrapment (Cl-Sph) than pentobarbital anesthesia, indicating that the vascular bed in the intestinal segment was constricted and ...

1985-04-01

113

Intestinal circulation during inhalation anesthesia  

International Nuclear Information System (INIS)

This study was designed to evaluate the influence of inhalational agents on the intestinal circulation in an isolated loop preparation. Sixty dogs were studied, using three intestinal segments from each dog. Selected intestinal segments were pumped with aortic blood at a constant pressure of 100 mmHg. A mixture of _8_6Rb and 9-microns spheres labeled with "1"4"1Ce was injected into the arterial cannula supplying the intestinal loop, while mesenteric venous blood was collected for activity counting. A very strong and significant correlation was found between rubidium clearance and microsphere entrapment (r = 0.97, P less than 0.0001). Nitrous oxide anesthesia was accompanied by a higher vascular resistance (VR), lower flow (F), rubidium clearance (Cl-Rb), and microspheres entrapment (Cl-Sph) than pentobarbital anesthesia, indicating that the vascular bed in the intestinal segment was constricted and flow ...

114

Development of regional cerebral blood flow during childhood studied with Iodine-123-IMP SPECT  

International Nuclear Information System (INIS)

Regional cerebral blood flow (rCBF) was assessed with single photon emission computed tomography (SPECT), "1"2"3I-N-isopropyl-iodoamphetamine ("1"2"3I-IMP), and the Table-Look-Up method in 51 children (27 boys, 24 girls) considered neurologically normal and aged 1 month to 15 years (mean age, 4 years 1 month; standard deviation (SD) 3 years 11 months) divided into seven age groups. The rCBF was measured in cortical regions, the cerebellum, thalamus, and the head of the caudate nucleus. Curves for reference values and standard deviations were defined for each region. The rCBF rapidly increased until 2 years of age, reaching maximum values during the third to fifth periods (2 to 10 years of age) in each region. The rCBFs then decreased, reaching adult levels at 10 to 15 years of age. The rCBF reached maximum values later in the frontal region than in other regions. The rCBF during the early period increased most prominently in the occipital ...

2006-06-01

115

Characteristics of meningioma scintigraphy with multiple brain imaging agents  

International Nuclear Information System (INIS)

Purpose: To clarify the characteristics of meningioma scintigraphy with multiple brain imaging agents and to evaluate their roles in diagnosis of meningiomas. Methods: Blood flow, "9"9"mTc-ECD, "9"9"mTc-DTPA, and/or "9"9"mTc-MIBI brain imagings were performed in 21 patients with meningiomas (3 malignant, 18 benign) proved by surgery and pathology. CT/MRI examinations were also made within one month. Characteristics of meningioma images were analyzed and uptake ratios were calculated. Results: In 16 of 20 patients, increased radioactivity during the arterial phase in the blood flow image was seen. Concave round or oval defects with smooth contour in the cerebral cortex were observed in 17 of 19 patients with "9"9"mTc-ECD, depression of frontoparietal cortex was found in one case and no abnormality in the other. A homogeneous accumulation of radioactivity in area corresponding to the defect in ...

1998-08-01

116

Cerebral blood flow measurement using stable xenon CT with very short inhalation times  

Energy Technology Data Exchange (ETDEWEB)

A noninvasive, simplified method using inhalation of stable xenon (Xe{sup s}) and computed tomographic (CT) scanning to estimate regional cerebral blood flow (rCBF) and regional partition coefficient (r{lambda}) is described. Twenty-four patients with cerebrovascular occlusive disease and six volunteer controls inhaled 30% Xe{sup s} and 70% oxygen for 180 seconds and exhaled for 144 seconds during serial CT scanning without denitrogenation. The end-tidal Xe{sup s} concentration was continuously monitored with a thermoconductivity analyzer to determine the build-up range (A value) and build-up rate constant (K value) for arteries with the curve fitting method. The time-CT number (Hounsfield unit) curve for cerebral tissue during the Xe{sup s} washin and washout phases was used to calculate r{lambda} and rCBF using least squares curve fitting analysis. The resultant r{lambda} and rCBF map demonstrated a reliable distribution between the gray and ...

1991-02-01

117

Cerebral blood flow measurement using stable xenon CT with very short inhalation times  

International Nuclear Information System (INIS)

A noninvasive, simplified method using inhalation of stable xenon (Xe"s) and computed tomographic (CT) scanning to estimate regional cerebral blood flow (rCBF) and regional partition coefficient (r#lambda#) is described. Twenty-four patients with cerebrovascular occlusive disease and six volunteer controls inhaled 30% Xe"s and 70% oxygen for 180 seconds and exhaled for 144 seconds during serial CT scanning without denitrogenation. The end-tidal Xe"s concentration was continuously monitored with a thermoconductivity analyzer to determine the build-up range (A value) and build-up rate constant (K value) for arteries with the curve fitting method. The time-CT number (Hounsfield unit) curve for cerebral tissue during the Xe"s washin and washout phases was used to calculate r#lambda# and rCBF using least squares curve fitting analysis. The resultant r#lambda# and rCBF map demonstrated a reliable distribution between the gray and white matter, and ...

118

A study of relative regional cerebral blood flow using N-isopropyl-p-["1"2"5I]-iodoamphetamine ("1"2"5I-IMP) in carbon monoxide exposed rats  

International Nuclear Information System (INIS)

The influence of carbon monoxide (CO) exposure on regional cerebral blood flow (r-CBF) in rat brain was studied using autoradiography and "1"2"5I-IMP. Fuji computed radiography (FCR) was used to obtain improved autoradiograms in this study. R-CBF was determined in a relative measure by calculating hippocampus/cortex and putamen/cortex ratios of RI accumulation from the autoradiogram using a densitometer. Comparison of autoradiograms with pathological findings in the area of the hippocampus and putamen yield the following results. In the animals that were exposed to 6400 ppm or 10000 ppm of CO for 30 minutes, and then were followed up for 2 weeks without further exposure, r-CBF was decreased but no pathological changes occurred. In the animals that were exposed to 6400 ppm or 10000 ppm of CO, and then were followed up for 4 weeks without further exposure, pathological changes appeared. In animals exposed to 3200 ppm of CO, the r-CBF tended to ...

119

A study of relative regional cerebral blood flow using N-isopropyl-p-( sup 125 I)-iodoamphetamine ( sup 125 I-IMP) in carbon monoxide exposed rats  

Energy Technology Data Exchange (ETDEWEB)

The influence of carbon monoxide (CO) exposure on regional cerebral blood flow (r-CBF) in rat brain was studied using autoradiography and {sup 125}I-IMP. Fuji computed radiography (FCR) was used to obtain improved autoradiograms in this study. R-CBF was determined in a relative measure by calculating hippocampus/cortex and putamen/cortex ratios of RI accumulation from the autoradiogram using a densitometer. Comparison of autoradiograms with pathological findings in the area of the hippocampus and putamen yield the following results. In the animals that were exposed to 6400 ppm or 10000 ppm of CO for 30 minutes, and then were followed up for 2 weeks without further exposure, r-CBF was decreased but no pathological changes occurred. In the animals that were exposed to 6400 ppm or 10000 ppm of CO, and then were followed up for 4 weeks without further exposure, pathological changes appeared. In animals exposed to 3200 ppm of CO, the r-CBF tended to ...

1990-11-01

120

What will keep the lights on in Ontario: Responses to a policy short-circuit  

Energy Technology Data Exchange (ETDEWEB)

Ontario's electricity industry restructuring program is reviewed, with a view to identify the reasons behind the failure of deregulation which was expected to create competition, to stabilize, or even reduce, prices to consumers, and attract serious private sector investment for the construction of new generating capacity. The report painstakingly reviews the series of events which resulted in a steep rise in electricity rates during the summer of 2002, immediately after deregulation came into effect, which led to freezing retail electricity rates and related charges by the then Conservative provincial government, and the reversal of that decision by the newly-elected Liberal government in the fall of 2003, and plans to bring back retail hydro rates that reflect the cost of production. The authors provide a discussion of policy options and a series of recommendations that are expected to create incentives to reduce and shift demand, encourage the use of more energy-efficient ...

2003-12-01

121

Should fresh blood be recommended for intensive care patients?  

UK PubMed Central (United Kingdom)

Fresh blood has many potential advantages over older blood, but there is no evidence that these properties translate into clinical benefit for intensive care patients. The observational multicenter...Full Text Available

2010-01-01

122

New versus old blood - the debate continues  

UK PubMed Central (United Kingdom)

Since the inception of blood banking, refinements in laboratory processes have allowed for progressively longer storage times of red blood cells. Whilst advantageous for the logistics of stock management,...Full Text Available

2010-01-01

123

Differential control of systolic and diastolic blood pressure in blacks with essential hypertension.  

UK PubMed Central (United Kingdom)

OBJECTIVE: The risk of cardiovascular and renal diseases has been shown to be higher for systolic blood pressure than diastolic blood pressure. The aim of this study was to assess the differential control...Full Text Available

2004-03-01

124

Contribution to the radionuclide x-ray fluorescence analysis of human blood and plasma  

International Nuclear Information System (INIS)

A photon-induced x-ray fluorescence method allowing the simultaneous determination of iron, copper, zinc, bromine and rubidium in human blood and blood plasma samples is described. The method is reliable and has a good sensitivity for a wide range of elements. (author).

1986-04-01

125

Comprehensive Analysis of Blood Culture Performed at Nine University Hospitals in Korea  

UK PubMed Central (United Kingdom)

BackgroundOptimal blood culture performance is critical for successful diagnosis and treatment of sepsis. To understand the status of blood culture, we investigated several aspects...Full Text Available

2011-04-01

126

Blood pressure and blood lead concentration in bus drivers  

Energy Technology Data Exchange (ETDEWEB)

San Francisco bus drivers have an increased prevalence of hypertension. This study examined relationships between blood lead concentration and blood pressure in 342 drivers. The analysis reported in this study was limited to subjects not on treatment for hypertension (n = 288). Systolic and diastolic pressure varied from 102 to 173 mm Hg and from 61 to 105 mm Hg, respectively. The blood lead concentration varied from 2 to 15 ..mu..g/dL. The relationship between blood pressure and the logarithm of blood lead concentration was examined using multiple regression analysis. Covariates included age, body mass index, sex, race, and caffeine intake. The largest regression coefficient relating systolic blood pressure and blood lead concentration was 1.8 mm Hg/ln (..mu..g/dL). The coefficient for diastolic blood pressure was 2.5 ...

1988-06-01

127

Bioethics of the refusal of blood by Jehovah's Witnesses: Part 2. A novel approach based on rational non-interventional paternalism.  

UK PubMed Central (United Kingdom)

Most physicians dealing with Jehovah's Witnesses (JWs) who refuse blood-based treatment are uncertain as to any obligation to educate patients where it concerns the JW blood doctrine itself. They often...Full Text Available

1998-10-01

128

Applications and Experience with PCR-Based Assays to Predict Blood Group Antigens  

UK PubMed Central (United Kingdom)

SummaryDNA-based tests are increasingly being used to predict a blood group phenotype. This is possible because genes encoding 29 of the 30 blood group systems have been cloned and sequenced,...Full Text Available

2009-01-01

129

Relationship of blood lead to blood pressure in a longitudinal study of working men  

Energy Technology Data Exchange (ETDEWEB)

The relationship of lead exposure to blood pressure has been examined in a longitudinal study of a cohort of 89 Boston, Massachusetts, policemen. At the baseline examination, subjects had a blood lead determination and three consecutive blood pressure measurements. Triplicate blood pressure measurements were also taken at years 3, 4, and 5. Multivariate analysis revealed that, after correction for previous systolic blood pressure, body mass index, age, and smoking, a high level of blood lead was a significant predictor of subsequent elevation of systolic pressure. Bootstrap simulations of these models provided supporting evidence for the observed associations. These data suggest that lead exposure can significantly affect systolic pressure.

1986-05-01

130

Prolonged Blood Storage Does Not Effect Survival in an Animal Model of Hemorrhagic Shock  

British Library Electronic Table of Contents (United Kingdom)

Summary Background: Red blood cell (RBC) transfusion in hemorrhagic shock is life saving. However, several clinical trials have shown that blood transfusion in the critically ill patient might be associated with adverse outcomes. Furthermore, an association between prolonged blood storage and adverse effects of RBC transfusion has been postulated. The aim of this study is to examine the effect of blood storage time on resuscitation outcome, in an animal model of hemorrhagic shock. Methods: 20 Wistar rats were phlebotomized in order to induce reversible hemorrhagic shock. Half of them were resuscitated with blood stored for a short period of time (4 days), and the other ones were resuscitated with blood stored for a prolonged time (14 days). Blood samples for hemoglobin, pH, lactate, bicarb...

2011-01-01

131

PIXE analysis of chinese chicken-blood stone  

Energy Technology Data Exchange (ETDEWEB)

This paper reports the chemical compositions of chicken-blood stone Ji Xue Shi measured by Proton Induced X-ray Emission (PIXE). The experimental result show that for the red portion of chicken-blood stone, the concentration of Hg is as high as 20 wt%, and the concentration of S can be above 10 wt%. For the non-red portion the main chemical compositions are Al{sub 2}O{sub 3} and SiO{sub 2}. The obtained chemical compositions are close to those of kaolinite for Balin chicken-blood stone, and of pyrophyllite for Changhua chicken-blood stone, respectively. So far many Changhua chicken-blood stones and Balin chicken-blood stones were found in China, the PIXE method can be used to explore the provenance of available chicken-blood stones. (author)

1999-07-01

132

Hydrolysis of cis- and trans-Epoxyeicosatrienoic Acids by Rat Red Blood Cells  

UK PubMed Central (United Kingdom)

Erythrocytes serve as reservoirs for cis- and trans-epoxyeicosatrienoic acids (EETs). Incubation of rat red blood cells (RBCs) with cis- and...Full Text Available

2008-07-01

133

Characteristics of compounds that cross the blood-brain barrier  

UK PubMed Central (United Kingdom)

Substances cross the blood-brain barrier (BBB) by a variety of mechanisms. These include transmembrane diffusion, saturable transporters, adsorptive endocytosis, and the extracellular pathways. Here,...Full Text Available

134

Autologous blood pleurodesis: A good choice in patients with persistent air leak  

UK PubMed Central (United Kingdom)

AIM:The study compares the efficiency, side effects and complications of autologous blood pleurodesis with talcum powder and tetracycline.MATERIALS...Full Text Available

2009-10-01

135

Investigation by physical methods of the possible role of telomeres in DNA in aging process  

CERN Document Server

The interaction energies between the different types of bases of a single strand of DNA molecule have been calculated. Using these original values of energies the harmonic behavior of a number of base patterns of DNA has been studied. In view of the great interest aroused by the discovery of the role of the telomere segment of the DNA in the replication process and its possible link with the aging process, we have investigated, with simple models, the harmonic behavior of the telomeric pattern of bases as well as the thermodynamic response in the biological system. With these results a conclusion on the probable role of the telomeric pattern on aging has also been drawn. Here the calculated values of harmonic frequencies of the telomeric pattern of bases and of other possible patterns show that the telomeric pattern is associated with the highest vibrational frequency among all patterns of base combinations at the ...

2003-01-01

136

Utility activities that create power quality problems  

Energy Technology Data Exchange (ETDEWEB)

Power quality problems are caused by activities normal to utility operations such as maintenance outages and capacitor switching or events that are abnormal such as lightning strikes and equipment failures. Disconnection and reconnection of transmission lines and transformers can cause switching surges, and are more severe on extra high voltage transmission lines than high voltage lines. Capacitor switching can cause transients and harmonics that may affect sensitive equipment, and are the source of 3rd, 5th, 7th and 9th harmonics in the hundreds of hertz ranges. Overload, sudden loss of generating capacity and transmission line faults are typical problems affecting system stability. Fault interruptions and reclosings can cause surges in the distribution system, and lightning strikes may cause voltage surges or dips due to arrester sparkover. Blackouts, brownouts, voltage fluctuations, travelling wave overvoltages, capacitor restrikes, ...

1992-02-01

137

Pion-induced fission  

Energy Technology Data Exchange (ETDEWEB)

The A(..pi../sup +/,/sup 3/He)B reaction near threshold is studied in a model where the pion is absorbed by an /sup 4/He constituent of the target nucleus. The predictions of this model using harmonic oscillator cluster wave functions agree semi-quantitatively with the experimental data on the inverse reaction.

1982-03-10

138

NSF/Tokyo Report: MITI's Polymer Project  

Science.gov (United States)

... Highly-Functional Materials" was launched in JFY1996 under the New Materials field. This project was ... Bio-mimetic materials" (1) Advanced stimuli responsive materials (2) Harmonized molecular materials ...

139

Efficient Second Harmonic Conversion of Broadband High ...  

Science.gov (United States)

... Rev. Lett., vol. 42, no. 24, pp. 1625-1628, June 1979. 3 ... Trans. Plasma Science, vol. PS-10, no. 1, pp. 55-58, March 1982. ...

1989-06-23

140

Effects of introducing low-frequency harmonics in the perception of vocoded telephone speech1  

UK PubMed Central (United Kingdom)

Several studies have demonstrated that telephone use presents a challenge for most cochlear implant (CI) users, and this is attributed mainly to the narrow bandwidth (300–3400 Hz) introduced...Full Text Available

2010-09-01

141

Discrimination of Schroeder-Phase Harmonic Complexes by Normal-Hearing and Cochlear-Implant Listeners  

UK PubMed Central (United Kingdom)

The temporal fine structure (TFS) of sound contributes significantly to the perception of music and speech in noise. The evaluation of new strategies to improve TFS delivery in cochlear implants (CIs)...Full Text Available

2008-03-01

142

In-vivo blood velocity and velocity gradient profiles downstream of stented and stentless aortic heart valves  

DEFF Research Database (Denmark)

BACKGROUND AND AIM OF THE STUDY: Abnormal flow conditions across aortic bioprosthetic valves may result in degenerative processes. Thus, it is important to implant biological valve prostheses with velocity profiles similar to those of native valves. The study aim was to compare blood velocity and velocity gradient profiles downstream of stented and stentless aortic valves implanted in pigs, and in native porcine valves. METHODS: Stented valve prostheses (Mitroflow, n = 7) or stentless valve prostheses (Solo, n = 5 or Toronto SPV, n = 7) were implanted into pigs; the native valve was retained in eight animals. After weaning the animals from cardiopulmonary bypass, cardiac magnetic resonance imaging was performed to determine the blood velocities and velocity gradient profiles. RESULTS: The native valves had a significantly lower peakvelocity (92 +/- 26 cm/s) than the artificial valves (Solo: 247 +/- 107 cm/s; Toronto: 252 ...

2010-01-01

143

Nonlinear vibrations and chaos in electrostatic torsional actuators  

British Library Electronic Table of Contents (United Kingdom)

Electrostatic torsional micro-mirrors have wide spread use in different industries for diverse purposes. This paper investigates the development of superharmonics and chaotic responses in electrostatic torsional micro-mirrors near the pull-in condition. Appearance of nonlinear phenomena is investigated in models accounting for and disregarding the coupling of torsional and flexural deflections. Analysis of the system response to step and harmonic excitation reveals the appearance of DC and AC symmetry breaking. Increasing the amplitude of harmonic excitation, the response in the form of distinct superharmonics changes to a broad band response, where there is loss of periodicity and the response becomes chaotic. Accounting for flexural deflections in coupled model reduces the voltage thresh...

2011-01-01

144

Multi-megajoule Nd: glass fusion laser design  

Energy Technology Data Exchange (ETDEWEB)

New technologies make multi-megajoule glass lasers economically feasible. Laser architectures using harmonic switchout, target plane holographic injection, phase conjugation, continuous apodization and higher amplifier efficiencies have been devised. A plan for a multi-megajoule laser which can be built for an acceptable cost relies on manufacturing economies of scale and the demonstration of the new technologies presented here. These include continuous pour glass production, rapid harmonic crystal growth, switching of large blocks of power using larger capcaitors packed more economically and by using large identical parts counts.

1986-04-04

145

Harmonic oscillator representation in the theory of scattering and nuclear reactions  

Energy Technology Data Exchange (ETDEWEB)

The following questions, concerning the application of the harmonic oscillator representation (HOR) in the theory of scattering and reactions, are discussed: the formulation of the scattering theory in HOR; exact solutions of the free motion Schroedinger equation in HOR; separable expansion of the short range potentials and the calculation of the phase shifts; `isolated states` as generalization of the Wigner-von Neumann bound states embedded in continuum; a nuclear coupled channel problem in HOR; and the description of true three body scattering in HOR. As an illustration the soft dipole mode in the (11)Li nucleus is considered in a frame of the (9)Li+n+n cluster model taking into account three body continuum effects.

1995-01-01

146

Free electron laser seeded by ir laser driven high-order harmonic generation  

International Nuclear Information System (INIS)

Coherent x-ray production by a seeded free electron laser (FEL) is important for next generation synchrotron light sources. The authors examine the feasibility and features of FEL emission seeded by a high-order harmonic generation (HHG) of an infrared laser. In addition to the intrinsic FEL chirp, the longitudinal profile and spectral bandwidth of the HHG seed are modified significantly by the FEL interaction well before saturation. This smears out the original attosecond pulselet structure. The authors introduce criteria for this smearing effect on the pulselet and the stretching effect on the entire pulse. They discuss the noise issue in such a seeded FEL.

2007-01-08

147

Analysis of the reactive power consumption and the harmonics in the network by the non-linear electrical loads  

Energy Technology Data Exchange (ETDEWEB)

The non linear electrical loads can give rise to a number of disturbances in electrical power networks. Among them, the high consumption of relative power is to be noted and so is the several harmonic components which may be injected in the industry system and very often in the utility system. So, by using appropriate technical considerations, as well as measurements in typical special electrical loads, such negative effects are analyzed and ways of minimizing them are suggested. (author) 3 refs., 11 figs., 6 tabs.

1994-12-31

148

Practical application of a simplified vitamin B_1_2 radioassay  

International Nuclear Information System (INIS)

... blood serum patients radioimmunoassay sampling tracer techniques isotope

155

The present state of nuclear medicine practice in Japan; A report of the 3rd nationwide survey in 1992  

Energy Technology Data Exchange (ETDEWEB)

The Subcommittee for Surveillance of Nuclear Medicine Practice has implemented a survey for actual nuclear medicine practice in Japan every 5 years. This article reports on the third survey implemented during a one-month period in June 1992. Questionnaires were sent to all 1256 facilities employing radiopharmaceuticals in routine practice, and 1162 (92.5%) answered. In vivo nuclear medicine examinations per day were performed in 6600 cases. SPECT accounted for 19.4%, as compared with 7.1% in the 1987 survey. According to organs, the frequency of examination for the cerebrospinal region was 3.2 and 2.2 times higher than that in the 1982 and 1987 surveys, respectively, whereas for the thyroid gland it was 0.6-fold and 0.7-fold that of these surveys. The proportion of bone scintigraphy was the highest (24.5%), followed by tumor scintigraphy (14.1%) and myocardial scintigraphy (11.9%). The frequency of myocardial and cerebral blood flow ...

1993-09-01

156

New technetium-99m radiopharmaceuticals for brain imaging  

International Nuclear Information System (INIS)

Radiopharmaceuticals for brain imaging are used for the detection of ischemia, tumours and dementia associatied with disorders of the blood flow in the brain. The current radiopharmaceuticals for brain imaging have various limitations: 2-(F-18)fluoro-2-deoxyglucose (F-18-FDG) has a very short half-life. The physical properties of di-#beta#-(piperidinoethyl)-(Se-75)selenide (Se-75-PIPSE) and di-#beta#-(morpholinoethyl)-(Se-75)-selenide (Se-75-MOSE) are not ideal. Thallium-201 diethyldithricarbamate (T1-201-DDC) has unfavourable nuclidic characteristics, limited availability, a long half-life and high cost. I-123 in N-isopropyl-p-iodoamphetamine (I-123-IMP) and N,N,N'-trimethyl-N'-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine (I-123-HIPDM) are not freely available and are expensive. N-13-labelled ammonia has a very short half-life. Technetium-99m hexamethylpropyleneamineoxime (Tc-99m-HM-PAO) is unstable both in vitro and in vivo and has a ...

1988-08-01

157

Natriuretic peptides in vascular physiology and pathology.  

Science.gov (United States)

Four major natriuretic peptides have been isolated: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP), and Dendroaspis-type natriuretic peptide (DNP). Natriuretic peptides play an important role in the regulation of cardiovascular homeostasis maintaining blood pressure and extracellular fluid volume. The classical endocrine effects of natriuretic peptides to modulate fluid and electrolyte balance and vascular smooth muscle tone are complemented by autocrine and paracrine actions that include regulation of coronary blood flow and, therefore, myocardial perfusion; modulation of proliferative responses during myocardial and vascular remodeling; and cytoprotective anti-ischemic effects. The actions of natriuretic peptides are mediated by the specific binding of these peptides to three cell surface receptors: type A natriuretic peptide receptor (NPR-A), type B natriuretic peptide ...

2008-01-01

158

Removal rate of ( sup 3 H)hyaluronan injected subcutaneously in rabbits  

Energy Technology Data Exchange (ETDEWEB)

Hyaluronan is an important constituent of the extracellular matrix in skin, and recent studies suggest that there is a pool of easily removable (free) hyaluronan drained by lymph. The removal rate of free hyaluronan in skin was measured from the elimination of ({sup 3}H)hyaluronan, injected subcutaneously in 13 rabbits. The removal of radioactivity was determined from appearance of {sup 3}H in plasma. During the first 24 h after injection, 10-87% of the tracer entered blood, less in injectates with high concentrations of hyaluronan. The removal was monoexponential with a half-life of 0.5-1 day when concentration of hyaluronan was 5 mg/ml or less. When hyaluronan concentration was 10 mg/ml or higher, the removal was slow for about 24 h and then became similar to that in experiments with low hyaluronan concentration. Free hyaluronan at physiological concentrations is thus turned over with the same rate as serum albumin, supporting the concept that hyaluronan is ...

1990-08-01

159

Radiotracer study of the preatomization behavior of lead in the graphite furnace  

Energy Technology Data Exchange (ETDEWEB)

The behavior of lead in the graphite furnace during the individual steps of the temperature program was investigated by means of /sup 203/Pb as a radiotracer. The matrix systems include HCl and HNO/sub 3/ solutions, 1% NaCl solution, blood, serum, urine, and the solid samples bovine liver and orchard leaves. Without matrix modificaton, a pyrolysis temperature of up to 500/sup 0/C can be used for all samples. Significant stabilization effects can be achieved in the preatomization steps by using NH/sub 4/H/sub 2/PO/sub 4/ and ammonia as matrix modifiers and by addition of hydrogen to the flowing argon gas. It was found that the use of a L'vov platform also helps to eliminate the matrix effects. With respect to lead stabilization and elimination of matrix effects, optimum experimental conditions are achieved by simultaneous use of a L'vov platform and NH/sub 4/H/sub 2/PO/sub 4/ as the matrix modifier. 34 references, 5 figures, 1 ...

1985-01-01

160

Radiotracer study of the preatomization behavior of lead in the graphite furnace  

International Nuclear Information System (INIS)

The behavior of lead in the graphite furnace during the individual steps of the temperature program was investigated by means of "2"0"3Pb as a radiotracer. The matrix systems include HCl and HNO_3 solutions, 1% NaCl solution, blood, serum, urine, and the solid samples bovine liver and orchard leaves. Without matrix modificaton, a pyrolysis temperature of up to 500"0C can be used for all samples. Significant stabilization effects can be achieved in the preatomization steps by using NH_4H_2PO_4 and ammonia as matrix modifiers and by addition of hydrogen to the flowing argon gas. It was found that the use of a L'vov platform also helps to eliminate the matrix effects. With respect to lead stabilization and elimination of matrix effects, optimum experimental conditions are achieved by simultaneous use of a L'vov platform and NH_4H_2PO_4 as the matrix modifier. 34 references, 5 figures, 1 table.

161

Radiopharmaceuticals for the imaging of functional abnormalities of the developing brain  

International Nuclear Information System (INIS)

The measurement of physiological parameters in man is possible with the help of positron emission tomography (PET) and radiopharmaceuticals labeled with short lived positron emitters as C 11, N 13, O 15 and F 18. With the use of this substances it is possible to make a tomographic map defining regional metabolic parameters in normal and diseased brain. This technique has therefore also be named 'in vivo autoradiography'. The possibility of applying C 11 or F 18 labeled deoxyglucose with PET for detecting regional and local changes in cerebral metabolic rate of glucose in brain development in children of 5 days to 1 year of age is discussed. Beyond this a relationship between cerebral metabolic rate of glucose, cerebral blood flow and cerebral metabolic rate of oxygen by use of this technique after inhalation of O 15 and C 11-labeled CO_2 is shown. Attention is drawn to the application of C 11-methyl-spiperone and PET to visualize dopamine ...

162

Radiohalogen-labeled imaging agents. 3. Compounds for measurement of brain blood flow by emission tomography  

Energy Technology Data Exchange (ETDEWEB)

The radioiodine-labeled amines currently available as brain-imaging agents, based on our previous work and that of others, are prepared either by exchange labeling or by direct iodination of a protected intermediate. The intrinsic slowness of these processes limits their potential for use with the positron-emitting 122I, as it has a half-life of only 3.6 min. This isotope has advantages of a low dose to the patient and availability from a generator containing the parent 20-h 122Xe. To develop a radiopharmaceutical in which 122I could be utilized, we prepared a number of secondary and tertiary amines (maintaining the 2,5-dimethoxy substitution pattern which allows direct iodination at the 4-position) with 131I. The organ distributions of these compounds were studied, and the best properties were found in the N,N-dimethyl homologue (2,5-dimethoxy-N,N-dimethyl-4-iodoamphetamine). This compound was successfully synthesized in a matter of seconds, with a chemical yield and radioactive ...

1984-08-01

163

Radiohalogen-labeled imaging agents. 3. Compounds for measurement of brain blood flow by emission tomography  

International Nuclear Information System (INIS)

The radioiodine-labeled amines currently available as brain-imaging agents, based on our previous work and that of others, are prepared either by exchange labeling or by direct iodination of a protected intermediate. The intrinsic slowness of these processes limits their potential for use with the positron-emitting 122I, as it has a half-life of only 3.6 min. This isotope has advantages of a low dose to the patient and availability from a generator containing the parent 20-h 122Xe. To develop a radiopharmaceutical in which 122I could be utilized, we prepared a number of secondary and tertiary amines (maintaining the 2,5-dimethoxy substitution pattern which allows direct iodination at the 4-position) with 131I. The organ distributions of these compounds were studied, and the best properties were found in the N,N-dimethyl homologue (2,5-dimethoxy-N,N-dimethyl-4-iodoamphetamine). This compound was successfully synthesized in a matter of seconds, with a chemical yield and radioactive ...

164

MRI of congenital heart disease in childhood  

International Nuclear Information System (INIS)

MRI provides a non-invasive diagnostic tool complementing echocardiography on one hand, and showing advantages over echocardiography, on the other hand, especially after corrective procedures. The multiple different MRI sequences need to be adapted to examinations of children and patients with congenital heart disease (CHD), and can be used to detect morphologic changes, blood-flow in the heart and thoracic vessels and diastolic or systolic function of myocardium. Several factors determine the success of the examination of a complex congenital heart disease or a postoperative situs. Pediatric radiologists and radiologists experienced in congenital heart diseases have to work in close cooperation. Echocardiography should be performed before MRI. The results of prior examinations and the clinical history of the patients, including possible palliative or reconstructive operations, must be available before MRI to guide the planning of the examination. With a systematic ...

2004-02-01

165

Lipiodol-CT findings of hepatocellular carcinoma: Correlation with lipiodol accumulation pattern and serum AFP  

Energy Technology Data Exchange (ETDEWEB)

Early diagnosis of hepatocellular carcinoma (hepatoma) along with surgical resection is the most appropriate therapeutic modality. For this purpose, there have been many reports concerning the diagnostic value of Lipiodol-CT scan. The authors selected 45 patients with hepatoma during the period of Feb.1986 to Jan. 1988 who received a conventional CT scan, hepatic angiography and a Lipiodol-CT scan. The results were as follows: 1. There was no statistical significant between serum AFP level and mass size, morphology and amount of necrosis. 2. Tumor necrosis was observed in a single massive and multinodular type when the tumor size exceeded 5 cm. 3. Pattern II on Lipiodol-CT, homogenous accumulation of Lipiodol except for the area of inner necrosis, was most frequently demonstrated, which means that a tumor mass with hypervascularity and increased blood flow will attract Lipiodol better. 4. Lipiodol-CT was superior to conventional CT in detecting ...

1989-12-15

166

Intersociety energy conversion engineering conference, 20th, Miami Beach, FL, August 18-23, 1985, Proceedings. Volumes 1, 2, and 3  

International Nuclear Information System (INIS)

Topics related to aerospace power are discussed, taking into account trends and issues of military space power systems technology, space station power system advanced development, the application and use of nuclear power for future spacecraft, the current status of advanced solar array technology development, the application of a parabolic trough concentrator to space station power needs, life test results of the Intelsat-V nickel-cadmium battery, and metal hydride hydrogen storage in nickel hydrogen batteries. Other subjects explored are concerned with alternative fuels, biomass energy, biomedical power, coal gasification, electric power cycles, and electric propulsion. Attention is given to an advanced terrestrial vehicle electric propulsion systems assessment, fuel cells as electric propulsion power plants, a sinewave synthesis for high efficiency dc-ac conversion, steam desulfurization of coal, leadless transfer of energy into the body to power implanted blood ...

1985-08-18

167

Dialysis and contrast media  

Energy Technology Data Exchange (ETDEWEB)

In a previous survey we revealed uncertainty among responders about (a) whether or not to perform hemodialysis in patients with severely reduced renal function who had received contrast medium; and (b) when to perform hemodialysis in patients on regular treatment with hemodialysis or continuous ambulatory dialysis who received contrast medium. Therefore, the Contrast Media Safety Committee of The European Society of Urogenital Radiology decided to review the literature and to issue guidelines. The committee performed a Medline search. Based on this, a report and guidelines were prepared. The report was discussed at the Ninth European Symposium on Urogenital Radiology in Genoa, Italy. Hemodialysis and peritoneal dialysis safely remove both iodinated and gadolinium-based contrast media. The effectiveness of hemodialysis depends on many factors including blood and dialysate flow rate, permeability of dialysis membrane, duration of hemodialysis and ...

2002-12-01

168

Clinical usefulness of Thallium-201 chloride scintigraphy for evaluation of oral malignant tumors. Relationship between retention index, histological type and tumor involvement  

Energy Technology Data Exchange (ETDEWEB)

In this report we assessed retrospectively the usefulness of Thallium-201 chloride scintigraphy for diagnosing malignant tumors of the maxillofacial region. Thallium-201 chloride scintigraphy was performed on 74 patients with malignant tumors and 8 patients with benign tumors, and a retention index was calculated from the early and delayed scintigrams (delayed accumulation ratio/ early accumulation ratio). This retention index depended on the blood flow of tumors and the affinity of tumors with Thallium-201 chloride. The retention index was large for malignant tumors (avg.: 1.05) and small for benign tumors (avg.: 0.78). Concerning the degree of malignancy (the histological type and the degree of tumor involvement), the retention index was higher in highly malignant tumors (1.20 for poorly-differentiated tumors and 1.19 for aggressive-involvement-type tumors) and lower for tumors of low malignancy (1.02 for well-differentiated tumors and 0.98 ...

1999-09-01

169

Brain imaging agents: synthesis and characterization of (N-piperidinylethyl) hexamethyl diaminodithiolate oxo technetium(V) complexes  

Energy Technology Data Exchange (ETDEWEB)

Two sup(99m)Tc complexes of (N-piperidinylethyl) hexamethyl diaminodithiol (NEP-DADT) have shown high brain uptake in rodents and lower primates. One of these sup(99m)Tc complexes has given positive images of the brain in man which are qualitatively related to regional brain blood flow (rCBF). In order to determine the structure of these sup(99m)Tc products, the corresponding /sup 99/Tc(NEP-DADT) complexes were prepared and characterized by HPLC, TLC, fast-atom-bombardment mass spectrometry (FAB MS) and other analytical techniques. These results indicate that the two /sup 99/Tc (NEP-DADT) complexes are syn and anti isomers (i.e. one isomer has the N-piperdinylethyl side chain located syn to the technetium oxo core while the other has this side chain located anti to the technetium oxo core).

1987-01-01

170

Brain imaging agents: synthesis and characterization of (N-piperidinylethyl) hexamethyl diaminodithiolate oxo technetium(V) complexes  

International Nuclear Information System (INIS)

Two sup(99m)Tc complexes of (N-piperidinylethyl) hexamethyl diaminodithiol (NEP-DADT) have shown high brain uptake in rodents and lower primates. One of these sup(99m)Tc complexes has given positive images of the brain in man which are qualitatively related to regional brain blood flow (rCBF). In order to determine the structure of these sup(99m)Tc products, the corresponding "9"9Tc(NEP-DADT) complexes were prepared and characterized by HPLC, TLC, fast-atom-bombardment mass spectrometry (FAB MS) and other analytical techniques. These results indicate that the two "9"9Tc (NEP-DADT) complexes are syn and anti isomers (i.e. one isomer has the N-piperdinylethyl side chain located syn to the technetium oxo core while the other has this side chain located anti to the technetium oxo core). (author).

171

Analysis of the quantitative structure activity relationship of technetium-99m-labeled diaminedithiol (DADT) and propyleneamineoxime (PAO) brain blood flow analogues  

Energy Technology Data Exchange (ETDEWEB)

In the search for new brain imaging agents for use with single photon emission computed tomography (SPECT), quantitative structure activity relationship (QSAR) analysis of the correlations between initial brain uptake and physicochemical parameters like lipophilicity, log P, molecular weight, log MW and log U/D (undissociated/dissociated), of the {sup 99m}Tc-DADT (diaminedithiol) complexes and {sup 99m}Tc-PAO (propyleneaminoxime) complexes have been analyzed. High correlations are found for both the {sup 99m}Tc-DADT complexes (r = 0.94) and for the {sup 99m}Tc-PAO complexes (r = 0.83) which are significant at 99.9 and 99.5 percentile level, respectively. These results will help the further design of better ligands for {sup 99m}Tc in brain imaging. (author).

1991-01-01

172

Non-selective cervical and cerebral three-dimensional rotational angiography  

International Nuclear Information System (INIS)

To evaluate the usefulness of three-dimensional (3D) rotational angiography, cervical carotid or cerebral angiography was done without catheterizing the branches of the thoracic aorta. A 5-Fr pig-tail type catheter was passed into the ascending aorta via the radial artery or the femoral artery. Optimal carotid angiogram views were obtained using approximately 45 ml of contrast medium at a flow rate of 15 ml/sec. Optimal cerebral angiogram views were obtained using approximately 70 ml of contrast medium at a flow rate of 20 ml/sec. The contrast medium concentration was 300 to 350 mgI/ml. A satisfactory view could be obtained in 5 of 8 (63%) cases on cervical carotid 3D angiography and in 8 of 14 (57%) cases on cerebral 3D angiography. In all cases, no complications were noted. This method offers the advantages of requiring a relatively short procedure time and a decrease in radiation exposure. Further studies are needed to determine the optimal ...

2007-09-01

173

The LW blood group glycoprotein is homologous to intercellular adhesion molecules.  

UK PubMed Central (United Kingdom)

The LW blood group antigens reside on a 42-kDa erythrocyte membrane glycoprotein that was purified by immunoaffinity and partially sequenced. From this information, a specific PCR-amplified DNA fragment...Full Text Available

1994-06-07

174

Study on effectiveness of transfusion program in thalassemia major patients receiving multiple blood transfusions at a transfusion centre in Western India  

UK PubMed Central (United Kingdom)

Background:Children suffering from beta-thalassemia major require repeated blood transfusions which may be associated with dangers like iron overload and contraction of...Full Text Available

2010-07-01

175

Statistical methods for the blood beryllium lymphocyte proliferation test.  

UK PubMed Central (United Kingdom)

The blood beryllium lymphocyte proliferation test (BeLPT) is a modification of the standard lymphocyte proliferation test that is used to identify persons who may have chronic beryllium disease. A major...Full Text Available

1996-10-01

176

Reduction in blood pressure with a low sodium, high potassium, high magnesium salt in older subjects with mild to moderate hypertension.  

UK PubMed Central (United Kingdom)

OBJECTIVE--To examine the effect of a reduced sodium and increased potassium and magnesium intake on blood pressure. DESIGN--Randomised double blind placebo controlled trial. SETTING--General population...Full Text Available

1994-08-13

177

Neurobehavioral Deficits and Increased Blood Pressure in School-Age Children Prenatally Exposed to Pesticides  

UK PubMed Central (United Kingdom)

BackgroundThe long-term neurotoxicity risks caused by prenatal exposures to pesticides are unclear, but a previous pilot study of Ecuadorian school children suggested that blood...Full Text Available

2010-06-01

178

Near-infrared spectroscopy technique to evaluate the effects of red blood cell transfusion on tissue oxygenation  

UK PubMed Central (United Kingdom)

IntroductionThe aim of this study was to evaluate the effects of red blood cell (RBC) transfusions on muscle tissue oxygenation, oxygen metabolism and microvascular reactivity in...Full Text Available

2009-01-01

179

Mapping strain exerted on blood vessel walls using deuterium double-quantum-filtered MRI  

UK PubMed Central (United Kingdom)

A technique is described for displaying distinct tissue layers of large blood vessel walls as well as measuring their mechanical strain. The technique is based on deuterium double-quantum-filtered (DQF)...Full Text Available

1998-04-14

180

Lethal Silver-Haired Bat Rabies Virus Infection Can Be Prevented by Opening the Blood-Brain Barrier?  

UK PubMed Central (United Kingdom)

Silver-haired bat rabies virus (SHBRV) infection induces a strong virus-specific immune response in the periphery of the host, but death is common due to the failure to open the blood-brain barrier...Full Text Available

2007-08-01

181

Insulin increases glucose transfer across the blood-brain barrier in man.  

UK PubMed Central (United Kingdom)

The influence of insulin on unidirectional flux of glucose across the blood-brain barrier and on net uptake of glucose by the brain was investigated in seven fasting patients. The unidirectional extraction,...Full Text Available

1981-03-01

183

In vitro assay for curative activity in blood of mice infected with Trypanosoma musculi.  

UK PubMed Central (United Kingdom)

An in vitro assay for curative antibody present in plasma of mice cured of Trypanosoma musculi is described. The assay involves the addition of plasma to a sample of infected blood, followed by hourly...Full Text Available

1986-08-01

184

Ibuprofen lysine (NeoProfen) for the treatment of patent ductus arteriosus  

UK PubMed Central (United Kingdom)

Patent ductus arteriosus (PDA) affects approximately 31% of infants whose birth weight is between 501 and 1500 g. The ductus arteriosus is a blood vessel that allows blood to bypass the pulmonary vasculature...Full Text Available

2007-01-01

185

Hypertension Outcomes Through Blood Pressure Monitoring and Evaluation by Pharmacists (HOME Study)  

UK PubMed Central (United Kingdom)

ObjectiveTo evaluate the effectiveness of a community pharmacist–based home blood pressure (BP) monitoring program.DesignTrial of a high-intensity...Full Text Available

2005-12-01

186

Hepatitis B antigen and antibody in the blood of prostitutes visiting an outpatient venereology department in Rotterdam.  

UK PubMed Central (United Kingdom)

We took blood samples from 128 prostitutes visiting the outpatient venereology department of the University Hospital, Rotterdam-Dijkzigt to test for the presence of hepatitis B surface antigen (HBsAg)...Full Text Available

1984-10-01

187

Gynura procumbens Merr. decreases blood pressure in rats by vasodilatation via inhibition of calcium channels  

UK PubMed Central (United Kingdom)

INTRODUCTION:Gynura procumbens has been shown to decrease blood pressure via inhibition of the angiotensin‐converting enzyme. However, other mechanisms that...Full Text Available

2011-01-01

188

Evidence for Diversity in Transcriptional Profiles of Single Hematopoietic Stem Cells  

UK PubMed Central (United Kingdom)

Hematopoietic stem cells replenish all the cells of the blood throughout the lifetime of an animal. Although thousands of stem cells reside in the bone marrow, only a few contribute to blood production...Full Text Available

2006-09-01

189

Effects of Sodium Pentobarbital Anesthesia and Leukocytosis on 'Escherichia coli' Mortality in Dog Blood 'In vitro'.  

Science.gov (United States)

Data reveal that sodium pentobarbital anesthesia does not depress glucose uptake of neutrophils stimulated by the addition of live E. coli. E. coli viability was reduced equally in blood obtained before and after sodium pentobarbital anesthesia. Pre- and ...

1978-01-01

190

Effect of oral contraceptives on blood pressure and on plasma renin, renin substrate, and corticosteroids  

UK PubMed Central (United Kingdom)

A rise in blood pressure associated with oral contraceptives is well established but the frequency with which it develops is not known. Early results from a controlled long-term prospective study have...Full Text Available

1969-01-01

191

Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries  

UK PubMed Central (United Kingdom)

IntroductionIn critically ill patients the relationship between the storage age of red blood cells (RBCs) transfused and outcomes are controversial. To determine if duration of RBC...Full Text Available

2009-01-01

192

Dried blood spots as a source of anti-malarial antibodies for epidemiological studies  

UK PubMed Central (United Kingdom)

BackgroundBlood spots collected onto filter paper are an established and convenient source of antibodies for serological diagnosis and epidemiological surveys. Although recommendations...Full Text Available

193

Distribution of lead-203 in human peripheral blood in vitro.  

UK PubMed Central (United Kingdom)

In-vitro experiments using 203Pb were performed to identify the lead binding components in human peripheral blood. The distribution of lead in plasma, in the red cell membrane, and within the red cell...Full Text Available

1980-02-01

194

Diagnostic comparison of malaria infection in peripheral blood, placental blood and placental biopsies in Cameroonian parturient women  

UK PubMed Central (United Kingdom)

BackgroundIn sub-Saharan Africa, Plasmodium falciparum malaria in pregnancy presents an enormous diagnostic challenge. The epidemiological and clinical relevance...Full Text Available

195

Diagnosis of Plasmodium falciparum infection using a solid-phase radioimmunoassay for the detection of malaria antigens  

UK PubMed Central (United Kingdom)

A serodiagnostic test has been developed for the detection of Plasmodium falciparum in infected blood. Using parasite antigens and infected red blood cells from in vitro...Full Text Available

1980-01-01

196

Comparison of deferral rates using a computerized versus written blood donor questionnaire: a randomized, cross-over study [ISRCTN84429599  

UK PubMed Central (United Kingdom)

BackgroundSelf-administered computer-assisted blood donor screening strategies may elicit more accurate responses and improve the screening process.MethodsRandomized...Full Text Available

197

Blood leukocyte DNA hypomethylation and gastric cancer risk in a high-risk Polish population  

UK PubMed Central (United Kingdom)

Global hypomethylation has been shown to increase genome instability potentially leading to increased cancer risk. We determined whether global methylation in blood leukocyte DNA was associated...Full Text Available

2010-10-15

198

Blood leucocyte count in the human fetus.  

UK PubMed Central (United Kingdom)

Total and differential leucocyte counts were measured in cord blood samples obtained by cordocentesis (n = 316) or at elective caesarean section (n = 11) from normal fetuses of between 18 and 40 weeks'...Full Text Available

1992-04-01

199

Blood Storage Duration and Biochemical Recurrence of Cancer After Radical Prostatectomy  

UK PubMed Central (United Kingdom)

OBJECTIVE: To test the hypothesis that perioperative transfusion of allogeneic and autologous red blood cells (RBCs) stored for a prolonged period speeds biochemical recurrence of prostate cancer...Full Text Available

2011-02-01

200

Blood Group A Antigen Is a Coreceptor in Plasmodium falciparum Rosetting  

UK PubMed Central (United Kingdom)

The malaria parasite Plasmodium falciparum utilizes molecules present on the surface of uninfected red blood cells (RBC) for rosette formation, and a dependency on ABO antigens has...Full Text Available

2000-05-01

201

Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study  

UK PubMed Central (United Kingdom)

IntroductionTransfusion is a common treatment in pediatric intensive care units (PICUs). Studies in adults suggest that prolonged storage of red blood cell units is associated with...Full Text Available

2010-01-01

202

An unusual clinical case of haemoptysis in spontaneous pneumothorax: blood clots within emphysematous bulla  

UK PubMed Central (United Kingdom)

We report an unusual case of spontaneous haemopneumothorax associated with haemoptysis due to blood clots within emphysematous bulla in a 42-year-old man. Haemoptysis disappeared after surgery.

203

Ameliorative Potential of Quercetin Against Paracetamol-induced Oxidative Stress in Mice Blood  

UK PubMed Central (United Kingdom)

The aim of the present study was to evaluate the ameliorative potential of quercetin (QC) against paracetamol (PCM)-induced oxidative stress and biochemical alterations in mice blood. A total of 36...Full Text Available

2011-07-01

204

ABO blood group phenotypes influence parity specific immunity to Plasmodium falciparum malaria in Malawian women  

UK PubMed Central (United Kingdom)

BackgroundBlood group O has been significantly associated with increased placental malaria infection in primiparae and reduced risk of infection in multiparae in the Gambia, an area...Full Text Available

205

ABO blood group and the risk of placental malaria in sub-Saharan Africa  

UK PubMed Central (United Kingdom)

BackgroundIn malarious areas of the world, a higher proportion of the population has blood group O than in non-malarious areas. This is probably due to a survival advantage conferred...Full Text Available

206

A new resorbable device for ligation of blood vessels - A pilot study  

UK PubMed Central (United Kingdom)

BackgroundDuring surgery, controlled haemostasis to prevent blood loss is vital for a successful outcome. It can be difficult to ligate vessels located deep in the abdomen. A device...Full Text Available

207

A Novel Mouse Model of Red Blood Cell Storage and Post-Transfusion in Vivo Survival  

UK PubMed Central (United Kingdom)

BackgroundStorage of RBCs is necessary for an adequate blood supply. However, reports have identified potential negative sequelae of transfusing stored RBCs. An animal...Full Text Available

2009-08-01

208

Dependence of Energy Thresholds on Laser Radiation Wavelength in Initiation of Heavy Metal Azides  

CERN Document Server

The behavior of silver and lead azides (scaly and threadlike crystals, and compacted powders) in initiation of explosive decomposition by laser pulsed radiation has been investigated. Initiation energy thresholds in irradiation at wavelengths of 1064 nm, 532 nm, 354.7 nm, 266 nm corresponding to four laser radiation harmonics have been measured. Samples both uncovered and covered with a transparent dielectric (a quartz plate) with the compressive force of up to 0.5GPa were initiated. In the transparent spectral region (the first and second laser harmonics) of the heavy metal azide matrix the effect of covering the sample surface with a plate on initiation energy threshold was insignificant, whereas, in the region of bandgap absorption (the fourth harmonic) strong dependence of the initiation threshold on whether the surface under irradiation is uncovered or covered. The results obtained have been considered with the account ...

2010-01-01

209

Critical assessment of the Schroedinger picture of quantum mechanics  

Energy Technology Data Exchange (ETDEWEB)

We provide an example in which the Heisenberg and the Schroedinger pictures of quantum mechanics give different results, thus confirming the statement of P.A.M. Dirac that the two pictures may lead to inequivalent results. We consider a one-dimensional nonrelativistic charged harmonic oscillator (frequency {omega}{sub 0} and mass m), and take into account the action of the radiation reaction and the vacuum electromagnetic forces on the charged oscillator. We show that the Heisenberg picture gives the correct value, {Dirac_h}{omega}{sub 0}/2, for the ground state energy of the harmonic oscillator in both cases of classical and quantized vacuum fields. In the case of the Schroedinger picture, considering classical vacuum fields, and using a simple calculation for the classical radiation reaction force that is valid in the limit of large mass (mc{sup 2} >> {Dirac_h}{omega}{sub 0}), we obtain the value {Dirac_h}{omega}{sub 0} for the ...

2002-12-16

210

Tracer studies with carrier-free lead-203  

International Nuclear Information System (INIS)

... blood cells in vitro in vivo injection intake lead 203 man renal clearance uptake

1972-07-30

211

Massage Therapy  

Medline Plus

... Massage therapy can help the body release certain chemicals. These chemicals help us relax, improve blood circulation and get ...

213

Blood plasma concentration of somatomedin-C in patients with Cushing Syndrome  

International Nuclear Information System (INIS)

Portuguese 1984. p. 127. Brazil Giannella Neto, D. Santomauro, ATMG

1984-10-27

215

Significance of tests for HBeAg and anti-HBe in HBsAg positive blood donors.  

UK PubMed Central (United Kingdom)

A sensitive radioimmunoassay method for HBeAg and anti-HBe allowed 98.4% of HBsAg positive blood donors to be classified. HBeAg was more prevalent in blood donors under 30 years of age and anti-HBe...Full Text Available

1980-11-01

216

Clinical application of stable xenon CT-CBF studies without denitrogenation  

Energy Technology Data Exchange (ETDEWEB)

Noninvasive and simplified methods for estimating regional cerebral blood flow (CBF) and regional partition coefficient ({lambda}) using the inhalation of stable xenon (Xe{sup s}) and computed tomographic (CT) scanning are described. Thirty percent Xe{sup s} in 70% oxygen was inhaled for 240 seconds and exhaled for 160 seconds during serial CT scanning without denitrogenation in 26 patients with cerebrovascular diseases and four volunteer controls. During the investigation, the end-tidal Xe{sup s} concentration was continuously monitored with a thermoconductivity analyzer to determine the build-up range (A value) and build-up rate constant (K value) of the artery by the curve fitting method. Calculated A and K values were corrected by the following formulae reported previously: for patients aged 0-20 years, A{sub e} = 0.75A{sub a} + 2.15, K{sub e} = 0.67K{sub a} + 0.69; 21-40 years, A{sub e} = 0.56A{sub a} + 3.24, K{sub e} = 0.38K{sub a} + ...

1990-08-01

217

Clinical application of stable xenon CT-CBF studies without denitrogenation  

International Nuclear Information System (INIS)

Noninvasive and simplified methods for estimating regional cerebral blood flow (CBF) and regional partition coefficient (#lambda#) using the inhalation of stable xenon (Xe"s) and computed tomographic (CT) scanning are described. Thirty percent Xe"s in 70% oxygen was inhaled for 240 seconds and exhaled for 160 seconds during serial CT scanning without denitrogenation in 26 patients with cerebrovascular diseases and four volunteer controls. During the investigation, the end-tidal Xe"s concentration was continuously monitored with a thermoconductivity analyzer to determine the build-up range (A value) and build-up rate constant (K value) of the artery by the curve fitting method. Calculated A and K values were corrected by the following formulae reported previously: for patients aged 0-20 years, A_e = 0.75A_a + 2.15, K_e = 0.67K_a + 0.69; 21-40 years, A_e = 0.56A_a + 3.24, K_e = 0.38K_a + 1.12; 41-60 years, A_e = 0.91A_a + 1.95, K_e = 0.38K_a + ...

218

VLF wave stimulation by pulsed electron beams injected from the space shuttle  

International Nuclear Information System (INIS)

Among the investigations conducted on the space shuttle flight STS 3 March 1982 was an experiment in which a 1-keV, 100-mA electron gun was pulsed at 3.25 and 4.87 kHz. The resultant waves were measured with a broadband plasma wave receiver. At the time of flight the experimental setup was unique in that the electron beam was square wave modulated and that the shuttle offered relatively long times for in situ measurements of the ionospheric plasma response to the VLF pulsing sequences. In addition to electromagnetic response at the pulsing frequencies the waves exhibited various spectral harmonics as well as the unexpected occurrence of satellite lines around those harmonics. Both phenomena occurred with a variety of different characteristics for different pulsing sequences.

219

Saturation of relativistic Weibel instability and the formation of stationary current sheets in collisionless plasma  

International Nuclear Information System (INIS)

We have studied the features of formation and the possible stationary structures of a self-consistent magnetic field in a relativistic collisionless plasma, which are characteristic of a simple geometry of the Weibel instability that is well known in the nonrelativistic case. The universal condition is established, the growth rate is determined, and the criteria of saturation of the Weibel instability are analyzed for a broad class of anisotropic particle distribution functions (for definiteness, in application to an electron-positron plasma). A nonlinear equation of the Grad-Shafranov type describing the potential current structures is derived and its solutions are analytically studied. Special attention is paid to spatially harmonic, nonlinear current configurations with parameters determined by the properties of the initial homogeneous plasma subject to the Weibel instability. It is demonstrated that the magnetic field energy density in the obtained solutions ...

2008-12-01

220

Predicting moisture state of timber members in a continuously varying climate  

British Library Electronic Table of Contents (United Kingdom)

A prerequisite for a sensible estimate of moisture induced stresses in timber members is an accurate prediction of the members' moisture states during their service life. There are, however, an infinite number of possible moisture states for an arbitrary timber member in a natural varying climate. The naturally varying humidity is possible to describe as harmonic cycles, with different periods, superimposed. This work presents realizations of envelop curves over the possible moisture states in a timber member for some carefully chosen harmonic humidity variations. The calculations, on which the realizations were made, are based on a fully coupled transport model including a model for the influential sorption hysteresis of wood. A format containing required information suitable for assessin...

2011-01-01

221

Pharmaceutical applications of non-linear imaging  

British Library Electronic Table of Contents (United Kingdom)

Non-linear optics encompasses a range of optical phenomena, including two- and three-photon fluorescence, second harmonic generation (SHG), sum frequency generation (SFG), difference frequency generation (DFG), third harmonic generation (THG), coherent anti-Stokes Raman scattering (CARS), and stimulated Raman scattering (SRS). The combined advantages of using these phenomena for imaging complex pharmaceutical systems include chemical and structural specificities, high optical spatial and temporal resolutions, no requirement for labels, and the ability to image in an aqueous environment. These features make such imaging well suited for a wide range of pharmaceutical and biopharmaceutical investigations, including material and dosage form characterisation, dosage form digestion and drug rele...

2011-01-01

222

Irreversible Performance of a Quantum Harmonic Heat Engine  

CERN Document Server

The unavoidable irreversible losses of power in a heat engine are found to be of quantum origin. Following thermodynamic tradition a model quantum heat engine operating by the Otto cycle is analyzed. The working medium of the model is composed of an ensemble of harmonic oscillators. A link is established between the quantum observables and thermodynamical variables based on the concept of canonical invariance. These quantum variables are sufficient to determine the state of the system and with it all thermodynamical variables. Conditions for optimal work, power and entropy production show that maximum power is a compromise between the quasistatic limit of adiabatic following on the compression and expansion branches and a sudden limit of very short time allocation to these branches. At high temperatures and quasistatic operating conditions the efficiency at maximum power coincides with the endoreversible result. The optimal compression ratio varies from the square ...

2006-01-01

223

High-gain harmonic generation free electron laser seeded by few-cycle laser  

International Nuclear Information System (INIS)

Tunable output wavelength is an important character of a free electron laser (FEL). As generally understood, to alter the wavelength of a high-gain harmonic generation (HGHG) FEL laser, the seed laser must be tunable. A few-cycle, high intensity laser obtained by optical compression usually has pretty broad bandwidth in the spectral domain, which can be used as the seed laser of a HGHG and may open the possibility to approach a HGHG scheme with fully tunable wavelength. In this paper, a HGHG FEL seeded by a few-cycle laser is theoretically discussed and numerically investigated. A few-cycle seed laser significantly influences HGHG FEL performance, especially in output wavelength tuning. For a HGHG FEL seeded by a 4-cycle 786 nm laser, output wavelength tunability range up to 14.9% of the central wavelength 262 nm is observed by adjusting the resonant condition.

2008-06-07

224

Development of the SSC (Superconducting Super Collider) trim coil beam tube assembly  

Energy Technology Data Exchange (ETDEWEB)

The Superconducting Super Collider uses approx. =9600 dipole magnets. The magnets have been carefully designed to exhibit minimal magnetic field harmonics. However, because of superconductor magnetization effects, iron saturation and conductor/coil positioning errors, certain harmonic errors are possible and must be corrected by use of multipole correctors called trim coils. For the most efficient use of axial space in the magnet, and lowest possible current, a distributed internal correction coil design is planned. The trim coil assembly is secured to the beam tube, a uhv tube with special strength, size, conductivity and vacuum. The report details the SSC trim coil/beam tube assembly specifications, history, and ongoing development.

1987-01-01

225

Cluster models of light nuclei and the method of hyperspherical harmonics: Successes and challenges  

International Nuclear Information System (INIS)

Hyperspherical-harmonics method to investigate the lightest nuclei having three-cluster structure is discussed together with recent experiments. Properties of bound states and methods to explore three-body continuum are presented. The challenges created by large neutron excess and halo phenomena are highlighted. Astrophysical aspects of the "7Li + n "#-># "8Li + #gamma# reaction and the solar-boron-neutrinos problem are analyzed. Three-cluster structure of highly excited states in "8Be is shown to be responsible for extreme isospin mixing. Progress in studies of "6He- and "1"1Li-induced inclusive and exclusive nuclear reactions is demonstrated, providing information on the nature of continuum structures of Borromean nuclei.

2009-08-01

226

A fast multipole transformation for global climate calculations  

Energy Technology Data Exchange (ETDEWEB)

A fast multipole transformation is adapted to the evaluation of summations that occur in global climate calculations when transforming between spatial and spherical harmonic representations. For each summation, the timing of the fast multipole transformation scales linearly with the number of latitude gridpoints, but the timing for direct evaluations scales quadratically. In spite of a larger computational overhead, this scaling advantage renders the fast multipole method faster than direct evaluation for transformations involving greater than approximately 300 to 500 gridpoints. Convergence of the fast multipole transformation is accurate to machine precision. As the resolution in global climate calculations continues to increase, an increasingly large fraction of the computational work involves the transformation between spatial and spherical harmonic representations. The fast multipole transformation offers a significant reduction in ...

1996-01-01

227

Reynolds Number Effects in Transonic Flow  

Science.gov (United States)

... of drag measurements with the AGARD Nozzle Afterbody ... are discussed separately from flows with a ... bubbles introduce typical flow phenomena that ...

1988-12-01

228

Flow Control  

Science.gov (United States)

... 65th AGARD Fluid Dynamics Symposium, Madrid, Spain, October ... of research programs on flow control ... separation, and delta wing flows formed the ...

1991-04-30

229

PROBE FOR FLOW PASSAGE INSPECTION  

J-STORE (Japan)

Full Text Available

2007-05-11

230

On Issues Concerning Flow Separation and Vortical Flows in Three ...  

Science.gov (United States)

impflrtant to the understanding of complex vortical flows. ... tions like the slender wing, flow separations are controlled in the s,. ...... 10, AGARD LS-121, Dec. ...

232

Industrial-process control valves Part2 : Flow capacity Section Four : Inherent flow characteristics and rangeability  

CERN Document Server

Industrial-process control valves Part2 : Flow capacity Section Four : Inherent flow characteristics and rangeability

1989-01-01

234

Importance of the Adrenal Gland Blood Supply During Laparoscopic Subtotal Adrenalectomy  

British Library Electronic Table of Contents (United Kingdom)

Abstract Introduction: Laparoscopic subtotal adrenalectomy (LSA) has emerged as a treatment option in the management of certain adrenal pathologies. After LSA, a satisfactory blood supply to the adrenal remnant is vital to preserve steroid function. The aim of this study was to review the adrenal blood supply with relevance to LSA. Materials and Methods: The adrenal blood supply was examined in three ways: 1) a review of six previous cadaver studies looking at adrenal blood supply; 2) a review of our 164 consecutive laparoscopic adrenalectomies (LAs) (January 1999?January 2009); the details of the main adrenal veins and variants had been prospectively recorded; and 3) dissection of 4 cadaver specimens (macroscopic and histologic examination was performed). Results: The six cadaver studies ...

2010-01-01

235

Association between the number of blood cultures and appropriateness of care for suspected bacteremic urinary tract infection in the elderly  

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to evaluate the association between the number of blood cultures collected and the appropriateness of care for suspected bacteremic community-acquired urinary tract infection (UTI) in the elderly. We retrospectively evaluated the medical records of 129 patients with UTI >65?years old admitted to a large community-based training hospital in Japan from 1 January 2006 to 31 December 2009. We assessed the association between the number of blood cultures collected and the appropriateness of care received, as well as other factors. Two-thirds of the patients were women, and patients >85?years old accounted for 45.0% of the cases. Most of the organisms isolated from the urine and blood were Escherichia coli (65.4?67.0%). More than two blood cultures were collected ...

2011-01-01

236

Lyophilized human whole blood for internal and external quality assurance of lead in blood assays  

Energy Technology Data Exchange (ETDEWEB)

Lyophilized human whole blood control material containing lead was prepared for internal and external quality assurance to evaluate and improve the analytical performance of lead. The samples were prepared in four different concentrations from outdated human whole blood stabilized with glucose and a citrate/phosphate buffer and provided under clean room conditions to avoid contamination. The lyophilized samples are easy to reconstitute with water. The materials were evaluated according to a statistical model. The lead concentrations in the specimens are close to blood lead levels usually following environmental and industrial exposure, particular in occupational health to the control of lead exposure at work regulations. The materials are available to the commercial as well as the scientific community. The Danish External Quality Assessment Scheme (DEQAS) for lead in blood is intended to complement the ...

1990-10-01

237

Transverse velocity modulator and generator schemes based on non-collinear radiation and electron beams  

International Nuclear Information System (INIS)

New non-collinear schemes are suggested for transverse velocity modulation of electron beams and for the generation of coherent spontaneous radiation by these transversely modulated beams. It is shown that due to the non-collinearity some orders of magnitude enhancement can be achieved for the coherent spontaneous radiation (CSR) power at both the fundamental and harmonic frequencies.

2000-05-01

238

The triaxial motion in Mo isotopes  

Energy Technology Data Exchange (ETDEWEB)

The nuclear shapes of transitional Mo isotopes are calculated by means of a model based on the cranking approximation and the Strutinksy method. The recent experimental results of the high-spin spectroscopy and lifetime measurement of [sup 87]Mo are studied in detail and explained by the evolution of the [gamma]-deformation with the quasiparticle configurations. The shape calculations with the modified-harmonic-oscillator potential give a critical neutron number N [>=] 47 for the spherical shape of the Mo isotopes. (orig.)

1993-11-22

239

The triaxial motion in Mo isotopes  

International Nuclear Information System (INIS)

The nuclear shapes of transitional Mo isotopes are calculated by means of a model based on the cranking approximation and the Strutinksy method. The recent experimental results of the high-spin spectroscopy and lifetime measurement of "8"7Mo are studied in detail and explained by the evolution of the #gamma#-deformation with the quasiparticle configurations. The shape calculations with the modified-harmonic-oscillator potential give a critical neutron number N #>=# 47 for the spherical shape of the Mo isotopes. (orig.).

240

Spontaneous radiation decay of weakly bound system in externa field  

International Nuclear Information System (INIS)

A new channel of nonlinear ionization of quantum system in a strong laser field is discussed. The probability of spontaneous radiation decay from the ground state in a short-range potential to the final Volkov wave function, is calculated by the first order of the perturbation theory. It is shown that this process at high intensities of the laser field will be comparable with the high harmonic generation. (orig.)

2001-02-01

241

P3 flux from anisotropic point source  

International Nuclear Information System (INIS)

One-velocity angular flux of a neutron field generated by a polarly anisotropic point source in an infinite homogeneous region is calculated in P3 approximation, using the spherical harmonics operator formalism adapted to two-dimensional spherical geometry. The problem is reduced to simple algebraic equations. For weak absorption and linearly anisotropic scattering, the solution is given in closed form. (orig.).

242

Optical second-harmonic generation in III-V semiconductors: Detailed formulation and computational results  

Science.gov (United States)

In an earlier paper (Phys. Rev. Lett. 66, 41 (1991)), we calculated both the dielectric constant ({epsilon}{sub {infinity}}) and the nonlinear optical susceptibilities for second-harmonic generation ({chi}{sup (2)}) in the static limit for AlP, AlAs, GaP, and GaAs in the local-density approximation with and without a self-energy correction in the form of a scissors operator,'' including local-field effects. In this paper, we expand our presentation of this calculation. Agreement with experiment to within 15% for the nonlinear susceptibility is demonstrated where experiments are available (GaP and GaAs); the dielectric constants are in no worse than 4% agreement with experiment. The virtual hole'' contributions are reformulated to avoid large numerical cancellations in the case of near degeneracies. The virtual electron'' terms dominate over the virtual hole'' terms by about one order of ...

1991-12-15

243

Nuclear level densities in self-consistent field approximation  

International Nuclear Information System (INIS)

The effect of two-body nature of the nuclear shell model potential on the recent numerical calculations of the nuclear level density has been examined. For the two most widely used single particle energy level schemes based on harmonic oscillator and Woods-Saxon potential, this effect is shown to significantly modify the excitation energy dependence of the level densities. (author).

1976-01-01

244

Monitoring interfacial dynamics by pulsed laser techniques. [Annual report  

Energy Technology Data Exchange (ETDEWEB)

Goal was developing optical methods for study of dynamic processes at the electrode/electrolyte interface. In the past year, optical second harmonic generation was used for time-resolved measurements of thallium deposition on Cu(111). The studies of carrier dynamics in photo-excited materials have involved both steady-state and picosecond time-resolved luminescence measurements following photoexcitation of the semiconductor material.

1992-12-31

245

Imaging Three Dimensional Two-Particle Correlations for Heavy-Ion Reaction Studies  

Energy Technology Data Exchange (ETDEWEB)

The authors report an extension of the source imaging method for analyzing three-dimensional sources from three-dimensional correlations. The technique consists of expanding the correlation data and the underlying source function in spherical harmonics and inverting the resulting system of one-dimensional integral equations. With this strategy, they can image the source function quickly, even with the extremely large data sets common in three-dimensional analyses.

2005-06-27

246

Higher harmonics of spontaneous radiation of ultrarelativistic channeled particles  

International Nuclear Information System (INIS)

The case of spontaneous radiation of channeled ultrarelativistic particles is considered when the dipolarity condition is not satisfied. The change of the particle longitudinal velocity affecting the maximum radiation frequency is included. The angular and frequency characteristics of the radiation for superhigh energies are studied for the first time. It is shown that there is an optimum energy at which the radiation density is maximum. The influence of the angle at which electrons enter a crystal and of the beam divergence on the radiation is investigated. The problem of quasichanneled particle radiation and also the radiation in axis-plane transitions are considered. (author).

1980-06-01

247

Feynman integrals and difference equations  

Energy Technology Data Exchange (ETDEWEB)

We report on the calculation of multi-loop Feynman integrals for single-scale problems by means of difference equations in Mellin space. The solution to these difference equations in terms of harmonic sums can be constructed algorithmically over difference fields, the so-called {pi}{sigma}{sup *}-fields. We test the implementation of the Mathematica package Sigma on examples from recent higher order perturbative calculations in Quantum Chromodynamics. (orig.)

2007-09-15

248

Coherent oscillator radiation  

International Nuclear Information System (INIS)

Coherent oscillator radiation is considered. A comparison is made with classical particle radiation with gauss distribution. Decay probability for coherent state in spontaneous radiation is estimated. The method suggested for describing harmonic oscillator allows to separate the effect of classical field radiation from quantum description of particle state within the framework of a self-consistent quantum mechanical problem.

1982-04-01

249

CRC handbook of laser science and technology. Volume 3. Optical materials, Part 1 - Nonlinear optical properties/radiation damage  

Energy Technology Data Exchange (ETDEWEB)

This book examines the nonlinear optical properties of laser materials. The physical radiation effects on laser materials are also considered. Topics considered include: nonlinear optical properties; nonlinear and harmonic generation materials; two-photon absorption; nonlinear refractive index; stimulated Raman scattering; radiation damage; crystals; and glasses.

1986-01-01

251

Flow deflector for nuclear fuel element assemblies  

International Nuclear Information System (INIS)

... coolants departure nucleate boiling fluid flow fluidic control devices fuel

252

Sudden infant death syndrome and placental disorders: the thyroid-selenium link.  

Science.gov (United States)

Placental insufficiency, inducing hypoxia-ischaemia, is considered a major cause of neuronal injury and impaired post natal development. Placental insufficiency alters the metabolism of arachidonic acid and its oxidation products. Premature labour and low-birth-weight infants are associated with reduced intrauterine blood-flow and infections of the reproductive tract. Thyroidal activity is depressed in undernutrition (placental insufficiency). Premature infants require extra vitamin C for normal tyrosine metabolism (tyrosine is the thyroxine precursor). Among the symptoms indicating infantile cretinism, which appear during 3-5 months of age are: delayed union of skull bones, torpid behaviour, slow feeding, cyanosis during feeding, excessive sleepiness, enlarged tongue, umbilical herniation, flabby musculature, short stature and delayed development. These symptoms have all been described in low-birth-weight infants and sudden infant death syndrome victims by various ...

1997-04-01

253

Mechanism of sup(99m)Tc-methylene diphosphonate (sup(99m)Tc-MDP) localization in experimental studies of bone tumors. Microautoradiography method  

Energy Technology Data Exchange (ETDEWEB)

(Materials and Methods) (I) VX/sub 2/ carcinoma was transplanted to the rabbit tibia, sup(99m)Tc-MDP was intravenously injected when bone destruction was radiologically seen. Preoperative scintigraphs, postoperative one of the resected tibia and fibra and scintigraphs of sliced tumor were compared with each other. Tissue fragments were collected from the sliced tumor, and RI was measured to compare concentration rates at different parts together with histological investigations. (II) Tetracycline was given to the rabbit of Experiment (I) to compare with the concentration of sup(99m)Tc-MDP. (III) Microautoradiography method was done on the experimental animals for investigation of the concentration of sup(99m)Tc-MDP. (Results) (I) Localization of sup(99m)Tc-MDP was increased at the sites of tumorous bone formation, of reactive bone formation at tumor edges, and of cartilage calcification, with little concentration at tumor cells or necrotic tissue. (II) Deposition sites of tetracycline ...

1981-12-01

254

In vitro atrazine-exposure inhibits human natural killer cell lytic granule release  

International Nuclear Information System (INIS)

The herbicide atrazine is a known immunotoxicant and an inhibitor of human natural killer (NK) cell lytic function. The precise changes in NK cell lytic function following atrazine exposure have not been fully elucidated. The current study identifies the point at which atrazine exerts its affect on the stepwise process of human NK cell-mediated lyses of the K562 target cell line. Using intracellular staining of human peripheral blood lymphocytes, it was determined that a 24-h in vitro exposure to atrazine did not decrease the level of NK cell lytic proteins granzyme A, granzyme B or perforin. Thus, it was hypothesized that atrazine exposure was inhibiting the ability of the NK cells to bind to the target cell and subsequently inhibit the release of lytic protein from the NK cell. To test this hypothesis, flow cytometry and fluorescent microscopy were employed to analyze NK cell-target cell co-cultures following atrazine exposure. These assays ...

2007-06-01

255

High-resolution brain SPECT imaging in attention deficit hyperactivity disorder children without comorbidity: quantitative analysis using statistical parametric mapping(SPM)  

Energy Technology Data Exchange (ETDEWEB)

We examined the abnormalities of regional cerebral blood flow(rCBF) in children with attention deficit hyperactivity disorder(ADHD) without comorbidity using statistical parametric mapping(SPM) method. We used the patients with not compatible to DSM-IV diagnostic criteria of ADHD and normal rCBF pattern in visual analysis as normal control children. Tc-99m ECD brain SPECT was performed on 75 patients (M:F=64:11, 10.0{+-}2.5y) with the DSM-IV diagnostic criteria of ADHD and 13 normal control children (M:F=9:4, 10.3{+-}4.1y). Using SPM method, we compared patient group's SPECT images with those of 13 control subjects and measured the extent of the area with significant hypoperfusion(p<0.01) in predefined 34 cerebral regions. Only on area of left temporal lobe showed significant hypoperfusion in ADHD patients without comorbidity (n=75) compared with control subjects(n=13). (n=75, p<0.01, extent threshold=16). rCBF of left ...

2002-07-01

256

Extracranial-intracranial bypass surgery utilizing homologous arterial grafts irradiated with high voltage cathode rays. Experimental study and clinical application  

Energy Technology Data Exchange (ETDEWEB)

Homologous and heterologous arterial segments were implanted in Fisher rats subcutaneously for the purpose of examining the antibody titer of the recipients' serum after implantation by means of the immune-adherence hemagglutination method. The antibody titer after implantation both of homologous and heterologous grafts decreased to 1/8 by 2.0 million (M) rads irradiation of high voltage cathode rays. The results suggested that high voltage cathode ray irradiation was not enough for heterologous graft to suppress its tissue reaction. Homografts taken from dogs 3 or 6 hours after sacrifice were irradiated with 2.0 M rads and transplanted in canine carotid artery using the technic of end-to-end anastomosis. Angiograms 6 months after operation revealed excellent patency rate in all the grafts of 28 dogs. furthermore, findings of the grafts from 1 week to 5 years after operation on scanning and transmission electron microscopies were evaluated. Clinical application of bypass ...

1982-06-01

257

Extracranial-intracranial bypass surgery utilizing homologous arterial grafts irradiated with high voltage cathode rays  

International Nuclear Information System (INIS)

Homologous and heterologous arterial segments were implanted in Fisher rats subcutaneously for the purpose of examining the antibody titer of the recipients' serum after implantation by means of the immune-adherence hemagglutination method. The antibody titer after implantation both of homologous and heterologous grafts decreased to 1/8 by 2.0 million (M) rads irradiation of high voltage cathode rays. The results suggested that high voltage cathode ray irradiation was not enough for heterologous graft to suppress its tissue reaction. Homografts taken from dogs 3 or 6 hours after sacrifice were irradiated with 2.0 M rads and transplanted in canine carotid artery using the technic of end-to-end anastomosis. Angiograms 6 months after operation revealed excellent patency rate in all the grafts of 28 dogs. furthermore, findings of the grafts from 1 week to 5 years after operation on scanning and transmission electron microscopies were evaluated. Clinical application of bypass surgery from ...

1982-01-01

258

Effects of exogenous norepinephrine on the spatial distribution of cardiac MIBG accumulation. Comparison with myocardial blood flow  

International Nuclear Information System (INIS)

Male rats were injected intravenously for 15 min with physiological saline (as control) (0.05 #mu#g/kg/min) or norepinephrine (NE) (0.1 #mu#g/kg/min) followed by 740 kBq of MIBG. Rats were injected for more 30 min (early stage group) and for more 4 hr (late stage group) with physiological saline or NE. Five MBq of "9"9"mTc-tetrofosmin (TF) was administered instead of MIBG in another group. The heart was isolated and uptake of MIBG or TF of right ventricle, apex, and left ventricle (divided into 8 parts) was measured. In control group, MIBG uptake of apex was significantly lower than that of lateral wall in both early and late groups. In NE group, MIBG uptake showed a tendency to decrease in both early and late groups. Compared with control group, the uptake of anterior wall in late group decreased significantly at NE 0.1 #mu#/kg/min. The TF uptake in control group was not different in each part. In NE group, the TF uptake of right ventricle decreased significantly compared with that of ...

1998-06-01

259

Effects of chronic swimming training on cardiac sarcolemmal function and composition.  

Science.gov (United States)

Cardiac contractile function is dependent on the integrity and function of the sarcolemmal membrane. Swimming exercise training is known to increase cardiac contractile performance. The purpose of the present study was to examine whether a swimming exercise program would alter sarcolemmal enzyme activity, ion flux, and composition in rat hearts. After approximately 11 wk of exercise training, cardiac myosin and actomyosin Ca2+-adenosinetriphosphatase (ATPase) activity was significantly higher in exercised rat hearts than in sedentary control rat hearts. Glycogen content was increased in plantaris and gastrocnemius muscles from exercised animals as was succinic dehydrogenase activity in gastrocnemius muscle of exercised rats in comparison to sedentary rat preparations. Sarcolemmal vesicles were isolated from hearts of exercise-trained and control rats. Sarcolemmal Na+-K+-ATPase and K+-p-nitrophenylphosphatase activities, Na+-Ca2+ exchange, and passive Ca2+ binding did not differ between ...

1989-04-01

260

Raman and SERS recognition of ?-carotene and haemoglobin fingerprints in human whole blood.  

Science.gov (United States)

The present work reports on Raman and Surface Enhanced Raman Scattering (SERS) vibrational fingerprints of ?-carotene and haemoglobin in fresh whole blood (i.e. right after blood test) with different laser excitations, i.e. visible (514 nm) and near-infrared (NIR, 785 nm). The use of colloidal silver nanoparticles significantly increases the Raman signal, thus providing a clear SERS spectrum of blood. The collected spectra have been examined and marker bands of ?-carotene and of the haem prosthetic group of haemoglobin have been found. In particular, the fundamental features of ?-carotene (514 nm excitation), blood proteins and haem molecules (785 nm excitation) were recognized and assigned. Moreover haemoglobin SERS signals can be identified and related with its oxygenation state (oxy-haemoglobin). The data reported show the prospects of Raman and SERS techniques to detect important bio-molecules in a ...

2011-03-26

261

Microgravity two-phase flow regime modeling  

Energy Technology Data Exchange (ETDEWEB)

A flow pattern or flow regime is the characteristics spatial distribution of the phases of fluid in a duct. Since heat transfer and pressure drop are dependent on the characteristic distribution of the phases, it is necessary to describe flow patterns in an appropriate manner so that a hydrodynamic or heat transfer theory applicable to that pattern can be chosen. The objective of the present analysis is to create a flow regime map based on physical modeling of vapor/liquid interaction phenomena in a microgravity environment. In the present work, four basic flow patterns are defined: dispersed flow, stratified flow, slug flow, and annular flow. Fluid properties, liquid and vapor flow rates, and pipe size were chosen as the principal parameters. It is assumed that a transition from ...

1987-01-01

262

Progress in developing a portable blood irradiator for medical applications  

International Nuclear Information System (INIS)

This year was spent in perfecting details of the new design blood irradiator, i.e., having male fittings made for shunt insertion and in acquiring preliminary biological data on its effectiveness. Fabrication of units was slowed by an unanticipated reaction of the resin with the steel injection mold, by occasional thrombogenic flaws in the blood interface layer, by thrombus formation at the points of connection to the shunt and by nonavailability of a reactor for activating the "1"6"9Tm to "1"7"0Tm. The remaining unsolved problem is that of thrombus formation at the connectors.

1977-05-01

263

Multielement XRF-analysis of blood from patients with dilated cardiomyopathy  

International Nuclear Information System (INIS)

Radionuclide x-ray fluorescence analysis was used for the determination of Fe, Zn, Br and Rb levels in whole blood from dilated cardiomyopathy patients and from a control group. The XRF-system consisted of a radionuclide source "1"0"9Cd, a semiconductor Si/Li detector connected to a multichannel analyzer. Fe content in blood of patients was significantly lower than that of the control. Zn content showed no deviation from normal range. Values for Br and Rb in patients highly exceed the range reported for them. (author) 4 tabs.; 9 refs.

1991-03-01

264

Idiopathic renal hematuria in a military working dog.  

Science.gov (United States)

A 1.5-year-old male Belgian Malinosis Military Working Dog presented with a 1-month history of intermittent hematuria. Diagnostic ultrasound and contrast radiography demonstrated large blood clots in the urinary bladder and a filling defect in the right renal pelvis. At surgery, clotted blood was present in the right ureter and bladder. Following right nephrectomy, the dog returned to training. One month later, elevations in urea nitrogen and creatinine were noted. Hematuria recurred at 3 months and the dog was found dead in its kennel. Necropsy showed a blood-filled left renal pelvis and ureter. PMID:1454185

1992-10-01

265

Effects of carbocalcitonin treatment on PAGET's disease assessed by quantitative bone scintigraphy  

International Nuclear Information System (INIS)

Sixteen patients with PAGET's disease of bone underwent quantitative bone scintigraphy with "9"9"mTc-MDP before and after a long-term treatment with carbocalcitonin, a synthetic analogue of eel calcitonin. The radionuclide study consisted in the blood pool and bone uptake measurement and in the bone avidity calculation (bone uptake - blood pool ratio). In our patients, a significant decrease in bone uptake and bone avidity was found, whereas the blood pool remained statistically unchanged. This behaviour could be accounted for the shift of the compact bone to a lamellar pattern. (orig.).

266

Effects of carbocalcitonin treatment on PAGET's disease assessed by quantitative bone scintigraphy  

Energy Technology Data Exchange (ETDEWEB)

Sixteen patients with PAGET's disease of bone underwent quantitative bone scintigraphy with /sup 99m/Tc-MDP before and after a long-term treatment with carbocalcitonin, a synthetic analogue of eel calcitonin. The radionuclide study consisted in the blood pool and bone uptake measurement and in the bone avidity calculation (bone uptake - blood pool ratio). In our patients, a significant decrease in bone uptake and bone avidity was found, whereas the blood pool remained statistically unchanged. This behaviour could be accounted for the shift of the compact bone to a lamellar pattern.

1988-06-01

267

Uptake and Retention of Adenine Moiety by Stored Human ...  

Science.gov (United States)

... Accession Number : AD0749455. Title : Uptake and Retention of Adenine Moiety by Stored Human Red Blood Cells. Descriptive Note : Interim rept.,. ...

1972-06-30

268

Titration of diphtheria and tetanus antitoxins in sera of low titre  

UK PubMed Central (United Kingdom)

Available methods for titrating diphtheria and tetanus antitoxin at low concentrations in human or animal blood are surveyed, with special attention to the amount of serum required for the test....Full Text Available

1971-01-01

269

The respiratory tract and the environment.  

UK PubMed Central (United Kingdom)

The primary determinants of pulmonary disease are environmental. The same thinness and delicacy of the air-blood barrier which allows rapid exchange of oxygen and carbon dioxide also reduce its effectiveness...Full Text Available

1977-10-01

270

TIGER in Antarctica - Q&A - Misc. Antarctic Topics - NASA  

Science.gov (United States)

Jan 5, 2004 ... Even if dinosaurs were cold-blooded, in the Mesozoic Era (when dinosaurs roamed the Earth), Antarctica was warm enough to have them. ...

273

Reporting Problems to FDA  

Medline Plus

Enter Search terms A-Z Index Home Food Drugs Medical Devices Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Radiation-Emitting Products Tobacco ...

275

Nutcracker Phenomenon and Nutcracker Syndrome  

UK PubMed Central (United Kingdom)

Nutcracker phenomenon refers to compression of the left renal vein, most commonly between the aorta and the superior mesenteric artery, with impaired blood outflow often accompanied by distention...Full Text Available

2010-06-01

276

Mesenchymal stem cell transplantation for diffuse alveolar hemorrhage in SLE  

British Library Electronic Table of Contents (United Kingdom)

Background. A 19-year-old girl was diagnosed with systemic lupus erythematosus, based on findings of arthritis, malar rash, positive antinuclear antibody test and high levels of antibodies to double-stranded DNA. Two months after diagnosis, the patient presented with a sudden drop in blood hemoglobin level. Several days later, she developed bloody sputum, rapidly progressive dyspnea and hypoxemia. High-resolution CT showed diffuse alveolar infiltrates in both lung fields.Investigations. Physical examination, complete blood count, erythrocyte sedimentation rate, urinalysis, 24-h urine protein excretion, fecal occult blood test, d-dimer test, acid hemolysis test, activated partial thromboplastin time and prothrombin time, direct and indirect Coombs tests, bone marrow smear, arterial blood ga...

2010-01-01

278

If I Had - A Family Member with Metabolic Syndrome  

Medline Plus

... elevated blood sugar levels, but not full-blown diabetes. What are the keys to preventing the disease? ... been well studied, in a study called The Diabetes Prevention Program, in several thousand people with this ...

280

Endothelial von Willebrand factor regulates angiogenesis  

UK PubMed Central (United Kingdom)

The regulation of blood vessel formation is of fundamental importance to many physiological processes, and angiogenesis is a major area for novel therapeutic approaches to diseases from ischemia to...Full Text Available

2011-01-20

282

Density Gradients for Isolation of Mononuclear Blood Cells for ...  

Science.gov (United States)

... to-continuum X-ray intensity ratio [5]. For ence in the means [7]. In addition, washing samples on thin films, the characteristic X- lymphocytes in NH ...

2011-05-15

283

Circulating Skeletal Stem Cells  

UK PubMed Central (United Kingdom)

We report the isolation of adherent, clonogenic, fibroblast-like cells with osteogenic and adipogenic potential from the blood of four mammalian species. These cells phenotypically resemble but are...Full Text Available

2001-05-28

284

Cholinesterase for Prophylactics of Poisoning by Organophosphorous Inhibitors  

International Science & Technology Center (ISTC)

The Production of Highly Active Human Blood Plasma Butyrylcholinesterase Preparation by Gene Engineering Methods to Create Protective Means against Poisoning by Organophosphorous Cholinesterase Inhibitors

285

Characteristics of transplacental lead transfer in rat dams and fetuses  

International Nuclear Information System (INIS)

This study was designed to quantitate the dose resulting from lead exposure during the critical periods of brain development during gestation by determining: (1) if blood lead concentration in rat dams is affected by pregnancy status or duration of lead exposure, (2) if lead concentration in fetuses is associated with the duration of dam exposure, (3) the rates of lead absorption and elimination in pregnant and nonpregnant dams; and (4) the effect that prebreeding exposure on lead kinetics in the dam and upon fetus blood lead concentrations. The results of experiments in which the dams' drinking water contained 50 mg/L lead indicate blood lead levels (after normalizing by water consumption on a body weight basis) of pregnant rats are significantly higher than blood lead levels of non-pregnant rats. Statistical differences in blood lead levels were observed by day 15 of gestation and ...

286

Blood gene expression markers to detect and distinguish target organ toxicity  

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study was to investigate whether the expression of specific genes in peripheral blood can be used as surrogate marker(s) to detect and distinguish target organ toxicity induced by chemicals in rats. Rats were intraperitoneally administered a single, acute dose of a well-established hepatotoxic (acetaminophen) or a neurotoxic (methyl parathion) chemical. Administration of acetaminophen (AP) in the rats resulted in hepatotoxicity as evidenced from elevated blood transaminase activities. Similarly, administration of methyl parathion (MP) resulted in neurotoxicity in the rats as evidenced from the inhibition of acetyl cholinesterase activity in their blood. Administration of either chemical also resulted in mild hematotoxicity in the rats. Microarray analysis of the global ...

2010-01-01

287

Antihypertensive Agents in Hemodialysis Patients: A Current Perspective  

UK PubMed Central (United Kingdom)

Hypertension affects most hemodialysis patients and is often poorly controlled. Adequate control of blood pressure is difficult with conventional hemodialysis alone but is important to improve...Full Text Available

2010-05-01

288

A search for the epidemic typhus agent in Ethiopian ticks*  

UK PubMed Central (United Kingdom)

The presence of antibodies to Rickettsia prowazeki in domestic animals from several parts of Africa, and the isolation of this rickettsia from the blood of goats and sheep and from...Full Text Available

1973-01-01

289

7 1 Will Technology, Incorporated X - Marshall Space Flight Center ...  

Science.gov (United States)

reemployment, retirement (CSRS and FERS) severance pay, benefits, ... Advance Sick Leave Program, Military Leave, leave for blood donation, Sick Leave for ...

290

Two-phase flow regime observations in a vertical hexagonal flow channel with and without a finned fuel bundle  

International Nuclear Information System (INIS)

Previous flow regime studies have been for horizontal, vertical, and inclined pipe flow. As such, only a few studies have been performed on bundle geometries. The present paper examines the flow regimes for a vertical hexagonal flow channel with and without a finned fuel bundle. This type of a 36 finned rod hexagonal fuel bundle in parallel hexagonal flow channels is used in a MAPLE (Multi- purpose Applied Physics Lattice Experimental) type nuclear reactor. An experiment apparatus was designed consisting of the flow channel, inlet plenum and an air-water separator. The inlet plenum is used to provide a uniform mixture of air and water before entering the hexagonal flow channel. A turbine flow meter is used to determine the water flow rate. The turbine flow meter is calibrated for ...

1990-12-10

291

Multiphase flow calculation software  

Energy Technology Data Exchange (ETDEWEB)

Multiphase flow calculation software and computer-readable media carrying computer executable instructions for calculating liquid and gas phase mass flow rates of high void fraction multiphase flows. The multiphase flow calculation software employs various given, or experimentally determined, parameters in conjunction with a plurality of pressure differentials of a multiphase flow, preferably supplied by a differential pressure flowmeter or the like, to determine liquid and gas phase mass flow rates of the high void fraction multiphase flows. Embodiments of the multiphase flow calculation software are suitable for use in a variety of applications, including real-time management and control of an object system.

2003-04-15

292

Hydrodynamics of swirling flow in a circular tube with sudden increase in cross-section and of the flow through a Borda mouthpiece  

Energy Technology Data Exchange (ETDEWEB)

By applying the mass, momentum, and angular momentum conservation laws and the maximum flow rate principle to swirling, effectively inviscid, incompressible flows in a circular tube with a sudden expansion and the direct-flow and reversed-flow Borda mouthpieces the dependence of the flow rate coefficient and mechanical energy losses on the radius ratio and nondimensional circulation is obtained. Several calculating approaches with potential and helical motion are introduced and investigated. In the case of helical motion, as the swirl decreases the axial core of the flow is found to close with a sudden change of the flow parameters.

1994-11-01

293

Wind Tunnel Flow Quality and Data Accuracy Requirements  

Science.gov (United States)

... tests, one often encounters, for instance, separated flows with large ... It is suspected that the flow-quality criteria given in AGARD Report No. ...

1982-11-01

294

Simulation of ground-water flow in the basin-fill aquifer of the Tularosa Basin, south-central New Mexico, ...  

Science.gov (United States)

... percent by interbasin ground-water flow into the Hueco Bolson, and 2 percent by flow into creeks and ... ...

295

RESEARCH ON FLOW SEPARATION IN WESTERN EUROPE  

Science.gov (United States)

... Separation," AGARD,Rept 272, April 1960, ... Leading Edge Effect on Supersonic Boundary Layer Flow." ... of Gas Injection in Separated Flows." TCEA, ...

1963-07-01

296

Perfect and Incompressible Fluid Flow in Turbomachines.  

Science.gov (United States)

A method for calculating flow through an airfoil cascade drawn on a surface of revolution is discussed. The three-dimensional flow was assumed to be represented by part-channels of varying width. The basic equations are the equation of continuity and the ...

1974-01-01

297

Large Eddy Simulation of Supersonic Turbulent Flow in ...  

Science.gov (United States)

... AGARD AR-319, Volume 2. Knight, D., Zhou ... a Turbulent Boundary Layer in a Supersonic Flow. ... of Development of Separated Flows in Compression ...

2001-08-01

298

Free Shear Layers, Base Pressure and Bluff-Body Drag  

Science.gov (United States)

... In: Separated Flows, AGARD CP No. ... on thin wings in two-dimensional incompressible flow. ... fields in the region of separating and reattaching flows. ...

1993-12-10

299

Control of Flow Separation Using Adaptive Airfoils  

Science.gov (United States)

... been demonstrated in steady compressible flows. ... steady Compressible Flow on an Oscillating Airfoil ... of Oscillating Airfoils", AGARD-CP-552, Aug. ...

1997-01-01

300

Calculation and Measurement of Transonic Flows over ...  

Science.gov (United States)

... including those with rear separation, ... flows ibout airfoils." AIAA Paper 'Jo 97-0419, 1987). ... "Effects of streamline curvature on turbulent flow." AGARD ...

1988-10-01

301

Asymmetric Vortex Flow Over Circular Cones  

Science.gov (United States)

... Calculations of asymmetric separated flow past circular ... in Missile Aerodynamics, AGARD CP 336 ... three-dimensional vortex flows in aerodynamics. ...

1991-03-01

302

Application of Synthetic Jets to Reduce Stator Flow Separation in a ...  

Science.gov (United States)

Surface pressure measurements at mid span indicate that flow separation begins near ..... Turbomachinery Flows, AGARD Propulsion Energetics Panel, 1998. ...

303

A Simple Model of Vortex Flow Past a Slender Elliptic Cone at ...  

Science.gov (United States)

... Calculations of asymmetric separated flow past circular ... in Missile Aerodynamics, AGARD-CP-336 ... Marconi Asymmetric separated flows about sharp ...

1990-09-01

304

Two-phase flow studies  

Energy Technology Data Exchange (ETDEWEB)

The two-phase flow program is directed at understanding the hydrodynamics of two-phase flows. The two-phase flow regime is characterized by a series of flow patterns that are designated as bubble, slug, churn, and annular flow. Churn flow has received very little scientific attention. This lack of attention cannot be justified because calculations predict that the churn flow pattern will exist over a substantial portion of the two-phase flow zone in producing geothermal wells. The University of Houston is experimentally investigating the dynamics of churn flow and is measuring the holdup over the full range of flow space for which churn flow exists. These experiments are being conducted in an air/water vertical two-phase flow loop. Brown ...

1983-12-01

305

Thermodynamics, lattice stability and defect structure of strontium silicides via first-principles calculations  

International Nuclear Information System (INIS)

The thermodynamics of the Sr-Si system is of fundamental importance for the understanding of eutectic modification of Al-Si alloys. At the same time, strontium silicides have recently been found to have potential applications in electronic devices. Renewed research efforts have led to a re-evaluation of the phase equilibria in this system, resulting in the discovery of previously undetected stable intermetallic compounds. In this work, we investigate the finite temperature thermodynamic properties of the stable (and metastable) Sr-Si intermetallics. The vibrational properties of the intermetallic compounds are calculated within harmonic theory, with quasi-harmonic corrections to account for the effects of thermal expansion. The total free energies of the compounds are computed considering vibrational and electronic contributions, as well as weak anharmonic corrections. The ground state of the system is predicted and compared to previous ...

2009-09-18

306

String Junctions and Holographic Interfaces  

CERN Document Server

In this paper we study half-BPS type IIB supergravity solutions with multiple $AdS_3\\times S^3\\times M_4$ asymptotic regions, where $M_4$ is either $T^4$ or $K_3$. These solutions were first constructed in [1] and have geometries given by the warped product of $AdS_2 \\times S^2 \\times M_4 $ over $\\Sigma$, where $\\Sigma$ is a Riemann surface. We show that the holographic boundary has the structure of a star graph, i.e. $n$ half-lines joined at a point. The attractor mechanism and the relation of the solutions to junctions of self-dual strings in six-dimensional supergravity are discussed. The solutions of [1] are constructed introducing two meromorphic and two harmonic functions defined on $\\Sigma$. We focus our analysis on solutions corresponding to junctions of three different conformal field theories and show that the conditions for having a solution charged only under Ramond-Ramond three-form fields reduce to relations involving the positions of the poles ...

2010-01-01

307

Nonlinear pulse evolution in seeded free-electron laser amplifiers and in free-electron laser cascades  

International Nuclear Information System (INIS)

The advances in laser technology have made available very short and intense laser pulses which can be used to seed a high-gain single-pass free-electron laser (FEL) amplifier. With these seed pulses, a regime of the FEL interaction where the radiation evolution is simultaneously dominated by nonlinear effects (saturation) and time-dependent effects (slippage) can be explored. This regime is characterized by the propagation of a solitary wavelike pulse where the power of the optical wave grows quadratically with time, its pulse length decreases and the spectral bandwidth increases. We analyze the interplay between the field and particle dynamics of this propagation regime which was studied before and termed super-radiance. Furthermore we analyze the properties of the strong higher-order harmonic emission from this wave and its behavior when propagating in a cascade FEL. The super-radiant pulse is indeed capable of passing through the stages of a cascade FEL and to ...

2005-08-15

308

Interim cryo-cooler/detector report  

Energy Technology Data Exchange (ETDEWEB)

This report describes development of an electronic system designed to reduce vibration generated by a cryocooler. The diminished vibration makes it practical to use the active cooler to extract heat from a portable gamma ray detector instrument. The system was developed for a Sunpower cryocooler with an integrated counterbalance mass. The overall momentum cancellation approach is also applicable to other similar cryocoolers. The cancellation system is an assembly of several components tailored to accomplish the required vibration reduction with minimum power consumption and volume. It is designed to be powered by a 18--32 Volt battery. Up to ten harmonics of the 58.65 Hz drive frequency are controlled. In addition to the vibration cancellation, the electronic system produces the drive signal for the cryocooler and regulates the cooler temperature. The system employs a sinusoidal drive to reduce the amount of higher harmonic vibration. A digital ...

1995-04-19

309

High-efficiency RF suppression circuit for fluorescent lamp inverters using charge pump and partial smoothinf capacitors; Chagi ponpu shiki korikiritsu bubun heikatsu hoshiki wo mochiita keikoto inbatayo kochoha teigen kairo  

Energy Technology Data Exchange (ETDEWEB)

A highly efficiency partial smoothing method is proposed to be used for inverters for 40W class household fluorescent inverters. In this system, the input current from the commercial AC power source is accumulated in a capacitor with comparatively small capacity as the electric charge, and then the lamp circuit is driven by the inverter utilizing the charging voltage of the capacitor and the charging voltage of the separately prepared partial smoothing capacitor. By this method, the RF harmonic components in the supply current can be decreased to improve the power factor with no complicated feedback controlling device. In addition, comparatively small capacity coils and capacitors can be used. The structure of the circuit and the operation of this proposed method are described, and the operational characteristic of the prototype circuit and the result of analysis are shown. Furthermore, problems and improving method of the actual circuit are investigated by an ...

1997-06-20

310

Gauge invariant perturbation theory in spatially homogeneous cosmology  

International Nuclear Information System (INIS)

The perturbations of the L.R.S. class A spatially homogeneous spacetimes are treated using Hamiltonian methods in conjunction with techniques from the theory of Lie group harmonic analysis. These latter techniques lead to a simple way of handling any set of tensor equations on these background spacetimes which has the same symmetry group as the space-time metric. Once this approach is developed, the Hamiltonian formulation is used to recover in a clean way the Bonanos equations for the perturbations of the perfect fluid models of the class of spacetimes under consideration. The conserved quantities associated with the four-dimensional symmetry group are evaluated and their role in the linearized Hamiltonian dynamics is discussed. The time-dependent linear canonical transformation of the linearized vacuum gravitational phase space adapted to Moncrief's gauge invariant decomposition is described in general for these models and evaluated explicitly for a class of ...

311

Development of quality assurance requirements - an international comparison  

International Nuclear Information System (INIS)

Total quality management strategy and the worldwide introduction of the DIN/ISO 9000 (EN 29 000) series of standards have given new impetus to traditional quality assurance. The most important change must surely be seen in the holistic approach of total quality management and its strict orientation towards customer requirements and satisfaction. International codes and standards for the nuclear industry will also have to be brought into line as part of the process of harmonizing quality assurance system standards. One possible approach is simply to specify a supplementary 'delta' of nuclear-specific requirements to be appended to the broad range of conventional requirements. It is a particular feature of quality-assured procedures in Germany that product and/or component related quality requirements and quality verifications are defined in the specifications of the architect engineer so that full implementation of the requirements from the design phase through to ...

312

Crystal growth, structural and optical characterization of a semi-organic single crystal for frequency conversion applications  

International Nuclear Information System (INIS)

Single crystals of semi-organic L-histidine hydrobromide have been grown by slow evaporation technique from a mixture of L-histidine and hydrobromic acid in aqueous solution at ambient temperature. From high-resolution X-ray diffraction analysis, the crystalline perfection of the grown crystal has been studied. Single crystal X-ray diffraction analyses, Nuclear Magnetic Resonance spectral analysis, Thermo-Gravimetry (TG), Differential Thermal Analysis (DTA) and hardness test have been employed to characterize the as-grown crystals. The UV cutoff wavelength of the grown crystal is below 300 nm and has a wide transparency window, which is suitable for second harmonic generation of laser in the blue region. Nonlinear optical characteristics have been studied using Q switched Nd:YAG laser (#lambda#=1064 nm). The second harmonic generation conversion efficiency of the grown crystals confirms their suitability for frequency conversion applications.

2010-12-15

313

The lateral hypothalamus as integrator of metabolic and environmental needs: From electrical self-stimulation to opto-genetics  

British Library Electronic Table of Contents (United Kingdom)

As one of the evolutionary oldest parts of the brain, the diencephalon evolved to harmonize changing environmental conditions with the internal state for survival of the individual and the species. The pioneering work of physiologists and psychologists around the middle of the last century clearly demonstrated that the hypothalamus is crucial for the display of motivated behaviors, culminating in the discovery of electrical self-stimulation behavior and providing the first neurological hint accounting for the concepts of reinforcement and reward. Here we review recent progress in understanding the role of the lateral hypothalamic area in the control of ingestive behavior and the regulation of energy balance. With its vast array of interoceptive and exteroceptive afferent inputs and its equ...

2011-01-01

314

Target identification of buried coated objects  

Scientific Electronic Library Online (English)

Abstract in english We consider the three dimensional electromagnetic inverse scattering problem of determining information about a buried coated object from a knowledge of the electric and magnetic fields measured on the surface of the earth corresponding to time harmonic electric dipoles as incident fields. We assume that the buried object is a perfect conductor that is (possibly) partially coated by a thin dielectric layer. No a priori assumption is made on the extent of the coating, i.e. (more) the object can be fully coated, partially coated or not coated at all. We present an algorithm based on the linear sampling method and reciprocity gap functional for reconstructing the shape of the scattering obstacle together with an estimate of the surface impedance of the coating.

2006-01-01

315

Polarized proton acceleration at the Brookhaven AGS  

Energy Technology Data Exchange (ETDEWEB)

At the conclusion of polarized proton commissioning in February 1986, protons with an average polarization of 45%, momentum of 21.7 GeV/c, and intensity of 2 x 10/sup 10/ protons per pulse, were extracted to an external polarimeter at the Brookhaven AGS. In order to maintain this polarization, five intrinsic and nearly forty imperfection depolarizing resonances had to be corrected. An apparent interaction between imperfection and intrinsic resonances occurring at very nearly the same energy was observed and the correction of imperfection resonances using ''beat'' magnetic harmonics discovered in the previous AGS commissioning run was further confirmed.

1986-01-01

316

Measurement of low-energy laser pulse duration in femtosecond range  

International Nuclear Information System (INIS)

Measurements of low-energy (#approx#10"- "1"0 J) femtosecond laser pulse durations have been carried out on the basis of second-order autocorrelation function analysis. The scheme of non collinear second harmonic generation realized in KDP crystal has been used for increasing of the measurement contrast and accuracy. Proposed scheme can be used for measurements in wide enough ranges of laser pulse durations (from tens femto seconds to hundreds picoseconds) and energies. (authors)

317

Magnetic fluctuation measurement in Sino United Spherical Tokamak plasma  

International Nuclear Information System (INIS)

To investigate the magnetic fluctuations and for further transport study, the poloidal and radial magnetic field measurement is conducted on the Sino United Spherical Tokamak (SUNIST). Auto-power spectral density indicates that the magnetic fluctuation energy mainly concentrates in the frequency region lower than 10 kHz. The magnetic field oscillations, which are characterized by harmonic frequencies of 40 kHz, are observed in the scrape-off layer; by contrast, in the plasma core, the magnetic fluctuations are of Gaussian type. The time-frequency profiles show that the poloidal magnetic fluctuations are temporally intermittent. The autocorrelation calculation indicates that the fluctuations in decorrelation time vary between the core and the edge. (authors)

2007-07-01

318

Generalized Tonnetze  

British Library Electronic Table of Contents (United Kingdom)

We study a generalization of the classical Riemannian Tonnetz to N-tone equally tempered scales (for all N) and arbitrary triads. We classify all the spaces that result. The torus turns out to be the most common possibility, especially as N grows. Other spaces include 2-simplices, tetrahedra boundaries, and the harmonic strip (in both its cylinder and Mobius band variants). The final and most exotic space we find is something we call a 'circle of tetrahedra boundaries'. These are the Tonnetze for spaces of triads which contain a tritone. They are closely related to Peck's Klein bottle Tonnetz.

2011-01-01

319

Electromagnetic characterization of superconducting radio-frequency cavities for gw detection  

International Nuclear Information System (INIS)

The electromagnetic properties of a prototype gravitational wave detector, based on two coupled superconducting microwave cavities, were tested. The radio-frequency (rf) detection system was carefully analysed. With the use of piezoelectric crystals small harmonic displacements of the cavity walls were induced and the parametric conversion of the electromagnetic field inside the cavities explored. Experimental results of bandwidth and sensitivity of the parametric converter versus stored energy and voltage applied to the piezoelectric crystal are reported. A rf control loop, developed to stabilize phase changes on signal paths, gave a 125 dBc rejection of the drive mode on a time scale of 1 h.

2004-03-07

320

A preliminary design for a one GHz NMR spectrometer magnet  

International Nuclear Information System (INIS)

The authors have performed a preliminary design for a persistent GHz NMR magnet at 23.5 T and 1.8 K operating conditions. In this paper the authors shall address the issues of realistic conductor selection, the coil design, the magnetic and mechanical analysis of the coil, and the required field uniformity. In addition, they shall describe the GHz magnet cryostat with a practical 1.8 K J-T refrigerator system. Finally vibration isolation system and field shield design and its associated field harmonics will be analyzed.

1993-09-20

321

Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma  

UK PubMed Central (United Kingdom)

The management of CNS tumors is limited by the blood-brain barrier (BBB), a vascular interface that restricts the passage of most molecules from the blood into the brain. Here we show that phage particles...Full Text Available

2011-01-04

322

Limiting-dilution analysis of T cells extracted from solid human lung tissue: comparison of precursor frequencies for proliferative responses and lymphokine production between lung and blood T cells from individual donors.  

UK PubMed Central (United Kingdom)

This study evaluates the frequency and functions of immunocompetent T cells at the clonal level in solid human lung tissue versus peripheral blood. Enzymatic digestion of slices of histologically normal...Full Text Available

1988-08-01

323

Iodine-123-labeled pH shift brain-imaging agents  

International Nuclear Information System (INIS)

HIPDM is an "1"2"3I-labeled agent with a distribution in brain reflecting regional perfusion. This compound is neutral and lipid soluble at blood pH and freely crosses the blood-brain barrier. At the lower pH in brain, it picks up a hydrogen ion and becomes positively charged. In this form the molecule is not lipid soluble and it is trapped in brain.

1982-05-03

324

Evaluation of Dry Chemicals by Photoacoustic Imaging  

Science.gov (United States)

In this study, an apparatus suitable to photoacoustic (PA) imaging to measure blood-analysis and urinalysis is fabricated and its measurement scheme has been established for the first time. The PA imaging of urinalysis test strip, blood sugar test strip, and cholesterol test strip is performed. A calibration curve of PA measurement is obtained for a urine test strip. The detectivity is better than that obtained by an eye-measurement.

1992-10-01

325

Effects of different concentrations of Maytenus ilicifolia (Espinheira Santa) on labelling of red blood cells and blood proteins with Technetium-99m  

International Nuclear Information System (INIS)

The use of natural products in all over the world has been increased in Brazil as well as in other countries. Maytenus ilicifolia is commonly used in popular medicine. The labeling of red blood cells (RBC) with technetium-99m ("9"9"m Tc) have been for many studies in nuclear medicine. This labeling procedure depends on a reducing agent and stannous chloride is normally used. Here, we investigate if the extract of Maytenus ilicifolia is capable to alter the labeling of RBC and blood proteins with "9"9"m Tc. Blood samples were incubated with Maytenus ilicifolia. Stannous chloride solution and Tc-99m were. Blood was centrifuged and plasma (P) and blood cells (C) were isolated. Samples of P or C were precipitated with trichloroacetic acid, centrifuged and IF and IF were separated. The percentage of radioactivity (% ATI) in C, IF-P and IF-C was calculated. The %ATI in decreased in C from ...

326

Effects of Pentobarbital Anesthesia on Survival, 'Escherichia coli' Clearance, Glucose and Leukocyte Concentration in Dogs Subjected to LD100. 'Escherichia coli'.  

Science.gov (United States)

This study was conducted to determine the effects of sodium pentobarbital anesthesia on survival of the dog, leukocyte response, E. coli clearance from the peripheral blood and blood glucose concentration in the leukocytotic endotoxin pre-injected canine ...

1978-01-01

327

DNA adducts in peripheral blood lymphocytes from aluminum production plant workers determined by 32P-postlabeling and enzyme-linked immunosorbent assay.  

UK PubMed Central (United Kingdom)

32P-Postlabeling analysis and enzyme-linked immunosorbent assay (ELISA) have been used to detect DNA adducts in peripheral blood lymphocytes from primary aluminum production plant workers who were exposed...Full Text Available

1993-03-01

328

Circulation and migration of small blood lymphocytes in the rat. I. Kinetics of lymphocyte circulation in the lymphoid organs.  

UK PubMed Central (United Kingdom)

Seventy male Wistar rats were the recipients of labeled small lymphocytes (1.5 X 10(7) each) collected from the peripheral blood of syngeneic donors. The migrating labeled lymphocytes were traced in...Full Text Available

1978-12-01

329

Chronic fatigue syndrome, XMRV and blood safety  

British Library Electronic Table of Contents (United Kingdom)

In the past few months, there has been public discussion relating to a new perspective on blood safety and specifically upon measures to prevent or discourage donation by individuals with a diagnosis of myalgic encephalopathy-chronic fatigue syndrome. This reflects an intriguing interplay between science, public health and public concern and illustrates some of the difficulties of making decisions in the face of uncertainty and inadequate information.

2011-01-01

330

Blood EPA and DHA Independently Predict All-Cause Mortality in Patients with Stable Coronary Heart Disease. The Heart and Soul Study  

UK PubMed Central (United Kingdom)

BackgroundOmega-3 fatty acid (n-3 FA) blood levels and intakes have been inversely associated with risk for sudden cardiac death, but their relationship with all-cause...Full Text Available

2010-07-01

331

A pre-clinical model of double versus single unit unrelated cord blood transplantation  

UK PubMed Central (United Kingdom)

Cord blood transplantation (CBT) with units containing total nucleated cell (TNC) dose >2.5×107/kg is associated with improved engraftment and decreased transplant-related...Full Text Available

2010-08-01

332

The hydroclimatology of the United States during El Nino/Southern Oscillation  

Energy Technology Data Exchange (ETDEWEB)

Palmer Drought Severity Index (PDSI) monthly data are analyzed, building on a previous study that investigated the influence of the El Nino/Southern Oscillation (ENSO) on US streamflow. Harmonic analysis is performed using data from 1,035 selected climatological stations, allowing observation of the biennial tendency in climate data. With the middle twelve months defined as the El Nino year (0), an idealized first harmonic fit to a 24-month ENSO composite is computed for each station. By plotting the first harmonic vectors of each station, regions of similar, or coherent, response are identified. The regions identified using PDSI data represent wet conditions in the Gulf of Mexico (Gm1 and GM2) and central (C) US, and dry conditions in the Pacific northwest (PNW) and northeast (NE) US. The PNW region exhibits the strongest interrelationship between ENSO and extreme drought events. Comparing PDSI data results with other ...

1995-12-31

333

Measurement of characteristics of an infrared free-electron laser with the L-band at Osaka University  

Energy Technology Data Exchange (ETDEWEB)

Free-electron laser (FEL) experiments have been conducted with the 38-MeV L-band electron linac at the Institute of Scientific and Industrial Research, Osaka University. It is a 1.3 GHz RF linac with a thermoionic gun, and equipped with two 12th and one 6th sub-harmonic prebunchers for producing the high-intensity single-bunch beam with a charge up to 67 nC/bunch. For oscillation experiments of FEL, the gun is replaced with that with a smaller cathode area in order to reduce the emittance of the beam. The normalized emittance has been measured to be 200 {pi} mm-mrad. The linac is operated in the long-pulse mode and one of the 12th sub-harmonic bunchers and the 6th sub-harmonic buncher are operated, so that the time duration of the macropulse is 4 {mu}s and the spacing between micropulses is 9.2 ns. The length of the micropulse is 30-40 ps and the charge in each micropulse is 2 nC. The electron beam from the linac is ...

1995-12-31

334

Is the Short Distance Scale a Result of a Problem with the LMC Photometric Zero Point?  

Energy Technology Data Exchange (ETDEWEB)

I present a promising route to harmonize distance measurements based on clump giants and RR Lyrae stars. This is achieved by comparing the brightness of these distance indicators in three environments: the solar neighborhood, Galactic bulge and Large Magellanic Cloud (LMC). As a result of harmonizing the distance scales in the solar neighborhood and Baade's Window, I derive the new absolute magnitude of RR Lyrae stars, M{sub v}(RR) at [Fe/H] = -1.6 (0.59 {+-} 0.05, 0.70 {+-} 0.05). Being somewhat brighter than the statistical parallax solution, but fainter than typical results of the main sequence fitting to Hipparcos data, these values of M{sub V}(RR) favor intermediate or old ages of globular clusters. Harmonizing the distance scales in the LMC and Baade's Window, I show that the most likely distance modulus to the LMC, {mu}{sub LMC} is in the range 18.24 - 18.44. The Hubble constant of about 70 km/s/Mpc ...

2004-03-29

342

Influence of iron deficiency in the radiopharmaceutical behavior of red blood cells labeled with "9"9"mTc("9"9"mTC-RBC)  

International Nuclear Information System (INIS)

Full text: Red blood cells (RBCs) labeled with "9"9"mTc are commonly used in the evaluation of cardiac function, gastrointestinal tract bleeding, red blood cell volume or splenic sequestration. Generally stannous ion is used as reducing agent. A proposed mechanism is that once the stannous ion (Sn) and the pertechnetate ("9"9"mTc) reach the interior of the RBC, the radionuclide is mainly house in the #beta#-chain of hemoglobin. The aim of this study was to determine if hemoglobin content reduction, an indicator of iron deficiency anemia, could affect the efficiency of RBC labeling and the biological distribution of this radiopharmaceutical. We studied 30 rats fed for 3 weeks after weaning with diets with iron contents of 6.5 ppm (group A), 18 ppm (group B) and 100 ppm (control). For all groups, the labeling yields were always higher than 97%; the percentage of radioactivity was mostly founded in blood with almost negligible ...

2005-11-09

343

Absence of detectable xenotropic murine leukemia virus-related virus in plasma or peripheral blood mononuclear cells of human immunodeficiency virus Type 1-infected blood donors or individuals in Africa  

British Library Electronic Table of Contents (United Kingdom)

BACKGROUND: Since the identification of xenotropic murine leukemia virus-related virus (XMRV) in prostate cancer patients in 2006 and in chronic fatigue syndrome patients in 2009, conflicting findings have been reported regarding its etiologic role in human diseases and prevalence in general populations. In this study, we screened both plasma and peripheral blood mononuclear cells (PBMNCs) collected in Africa from blood donors and human immunodeficiency virus Type 1 (HIV-1)-infected individuals to gain evidence of XMRV infection in this geographic region. STUDY DESIGN AND METHODS: A total of 199 plasma samples, 19 PBMNC samples, and 50 culture supernatants from PBMNCs of blood donors from Cameroon found to be infected with HIV-1 and HIV-1 patients from Uganda were screened for XMRV infecti...

2011-01-01

344

Theoretical and Experimental Investigation of Flamespreading ...  

Science.gov (United States)

... CHANNELS, TWO PHASE FLOW, WAVES, IGNITERS, GAS FLOW, HOWITZERS, CARTRIDGE CASES, COMBUSTIBLE CARTRIDGE CASES. ...

1986-02-01

345

Special Course on Three-Dimensional Supersonic ...  

Science.gov (United States)

... Dynamics Panel Executive AGARD 7 rue ... 4 AXIAL FLOW IN CORNERS AT SUPERSONIC ... AND HYPERSONIC FLOWS INCLUDING SEPARATION ...

1990-01-01

346

LAMINAR SEPARATION IN SUPERSONIC AND ...  

Science.gov (United States)

... Agard Report 272,1960 ... and reattached subsonic turbulent flows obtained downstream ... of flow separations due to deflected control surfaces. ...

1966-09-30

347

Diaphragm Rupture Effects on an Expanding Flow in a Tube.  

Science.gov (United States)

... The fundamental problem of diaphragm rupture was studied experimentally to determine the effects on an expanding flow in an evacuated tube. ...

1972-08-01

348

Application of neutron radiography to visualization of multiphase flows  

Energy Technology Data Exchange (ETDEWEB)

Visualizations by real-time neutron radiography are demonstrated of various flow patterns of nitrogen gas-water two-phase flow in a stainless-steel tube, water inverted annular flow in a stainless-steel tube, flashing flow in an aluminium nozzle and fluidized bed in aluminium tube and vessels. Photographs every 1/60 s are presented by an image processing method to show the dynamic behaviours of the various flow patterns. It is shown that this visualization method can be applied efficiently to multiphase flow researches and will be applicable to multiphase flows in industrial machines. (author).

1990-04-01

349

Application of neutron radiography to visualization of multiphase flows  

International Nuclear Information System (INIS)

Visualizations by real-time neutron radiography are demonstrated of various flow patterns of nitrogen gas-water two-phase flow in a stainless-steel tube, water inverted annular flow in a stainless-steel tube, flashing flow in an aluminium nozzle and fluidized bed in aluminium tube and vessels. Photographs every 1/60 s are presented by an image processing method to show the dynamic behaviours of the various flow patterns. It is shown that this visualization method can be applied efficiently to multiphase flow researches and will be applicable to multiphase flows in industrial machines. (author).

1990-01-01

350

Interfacial Area and Interfacial Transfer in Two-Phase Flow Systems (Volume IV. Chapters 15-19)  

Energy Technology Data Exchange (ETDEWEB)

Experiments were performed on horizontal air-water bubbly two-phase flow, axial flow, stratified wavy flow, and annular flow. Theoretical studies were also undertaken on interfacial parameters for a horizontal two-phase flow.

2003-03-15

351

Investigation of large amplitude stratified waves in a CANDU-type 37 rod nuclear fuel channel by a real-time neutron radiography technique  

Energy Technology Data Exchange (ETDEWEB)

A Real-Time Neutron Radiography (RTNR) system is used to determine two-phase flow parameters for a horizontal co-current two-phase flow channel with a CANDU-type 37 rod bundle. Image processing techniques are applied to visualize the two-phase flow, and to determine flow regime, cross-sectional averaged void fraction, time averaged void fraction, and void distribution. The experimentally determined flow regime map disagrees with existing flow regime models developed for the CANDU-type rod bundles. A new flow regime is observed and designated Large Amplitude Stratified Wavy flow. The results show that the LASW flow regime may be due to a combination of undeveloped flow phenomena, boundary conditions, and circumferential cross flow occurring in the bundle. The ...

1997-12-31

352

Investigation of large amplitude stratified waves in a CANDU-type 37 rod nuclear fuel channel by a real-time neutron radiography technique  

Energy Technology Data Exchange (ETDEWEB)

A real-time neutron radiography (RTNR) system is used to determine two-phase flow parameters for a horizontal co-current two-phase flow channel with a cylindrical 37 rod bundle. Image processing techniques are applied to visualize the two-phase flow, and to determine flow regime, cross-sectional averaged void fraction, time averaged void fraction, and void distribution. The experimentally determined flow regime map disagrees with existing flow regime models developed for the cylindrical rod bundles. A new flow regime is observed and designated large amplitude stratified wavy (LASW) flow. The results show that the LASW flow regime may be due to a combination of undeveloped flow phenomena, boundary conditions, and circumferential cross flow occuring in the ...

2000-08-01

353

Investigation of large amplitude stratified waves in a CANDU-type 37 rod nuclear fuel channel by a real-time neutron radiography technique  

International Nuclear Information System (INIS)

A Real-Time Neutron Radiography (RTNR) system is used to determine two-phase flow parameters for a horizontal co-current two-phase flow channel with a CANDU-type 37 rod bundle. Image processing techniques are applied to visualize the two-phase flow, and to determine flow regime, cross-sectional averaged void fraction, time averaged void fraction, and void distribution. The experimentally determined flow regime map disagrees with existing flow regime models developed for the CANDU-type rod bundles. A new flow regime is observed and designated Large Amplitude Stratified Wavy flow. The results show that the LASW flow regime may be due to a combination of undeveloped flow phenomena, boundary conditions, and circumferential cross flow occurring in the bundle. The ...

1997-10-04

354

Flow regime transfer conditions for two-phase flow in a fracture  

Energy Technology Data Exchange (ETDEWEB)

Between 25 and 30 percent of total known petroleum reserves are contained within oil-laden fractured reservoirs where the dominant flow path is through the fractures. Economic oil recoveries from fractured reservoirs depend on a better understanding of the flow in fractures and networks of fractures. However, the flow of heavy oil and water, and particularly the flow regime map for two-phase immiscible flow has received less attention in contrast with gas-liquid flow in fractures. This paper discussed the use of flow pattern observations in a Hele-Shaw cell to generate two-phase flow regime maps. The paper investigated the effect of fracture gap and fluid viscosities on flow regimes. A correlation based on different flow and fracture properties was developed to define ...

2010-07-01

355

Flow visualization II Proceedings of the Second International Symposium, Bochum, West Germany, September 9-12, 1980  

Energy Technology Data Exchange (ETDEWEB)

Applications, techniques, instrumentation, and interpretation of flow visualization are discussed. Methods of using flow visualization for the examination of combustion in furnaces, heat transfer with heat exchangers, and in fluid engines are explored, along with flow visualization in food processing, steel-casting, and process engineering. Further attention is given to pipe and channel flow, flow separation in laminar flow and around oscillating airfoils, wakes and vortices, supersonic flow and shock waves, and stratified flow and oceanography. The visualization of boundary layers is considered for various conditions, and applications for multiphase flow, rheology, and medical problems are detailed. Oil film, dry-surface coating, chemical, fluorescent, and minituft methods are presented, as well as ...

1982-01-01

356

Development of ultrasonic measurement technique for the determination of vertical two-phase flow pattern  

Energy Technology Data Exchange (ETDEWEB)

In the present study, a new measurement technique which uses a ultrasonic transmission signals in order to determine the vertical two phase flow pattern even under high pressure condition. The ultrasonic measurement system developed in the present study not only provides the measurement functions required for the determination of vertical two phase flow pattern but also makes the real time determination possible. The developed ultrasonic measurement system accurately determined the various vertical two phase flow patterns such as bubbly, slug, churn, annular flow etc. In addition to the determination of flow patterns, qualitative informations for each flow pattern can be obtained, which include void fraction in bubbly flow, length of slug bubble and liquid tail characteristics in slug flow, and stable or transient ...

2002-03-01

357

A two-phase flow regime map for a MAPLE-type nuclear research reactor fuel channel: Effect of hexagonal finned bundle  

Energy Technology Data Exchange (ETDEWEB)

A two-phase flow regime map is developed experimentally and theoretically for a vertical hexagonal flow channel with and without a 36-finned rod hexagonal bundle. This type of flow channel is of interest to MAPLE-type nuclear research reactors. The flow regime maps are determined by visual observations and observation of waveforms shown by a capacitance-type void fraction meter. The experimental results show that the inclusion of the finned hexagonal bundle shifts the flow regime transition boundaries toward higher water flow rates. Existing flow regime maps based on pipe flow require slight modifications when applied to the hexagonal flow channel with and without a MAPLE-type finned hexagonal bundle. The proposed theoretical model agrees well with experimental results.

1997-05-01

358

A two-phase flow regime map for a MAPLE-type nuclear research reactor fuel channel: Effect of hexagonal finned bundle  

International Nuclear Information System (INIS)

A two-phase flow regime map is developed experimentally and theoretically for a vertical hexagonal flow channel with and without a 36-finned rod hexagonal bundle. This type of flow channel is of interest to MAPLE-type nuclear research reactors. The flow regime maps are determined by visual observations and observation of waveforms shown by a capacitance-type void fraction meter. The experimental results show that the inclusion of the finned hexagonal bundle shifts the flow regime transition boundaries toward higher water flow rates. Existing flow regime maps based on pipe flow require slight modifications when applied to the hexagonal flow channel with and without a MAPLE-type finned hexagonal bundle. The proposed theoretical model agrees well with experimental results.

1997-01-01

359

An Experimental study on a Method of Computing Minimum flow rate  

International Nuclear Information System (INIS)

Many pump reliability problems in the Nuclear Power Plants (NPPs) are being attributed to the operation of the pump at flow rates well below its best efficiency point(BEP). Generally, the manufacturer and the user try to avert such problems by specifying a minimum flow, below which the pump should not be operated. Pump minimum flow usually involves two considerations. The first consideration is normally termed the 'thermal minimum flow', which is that flow required to prevent the fluid inside the pump from reaching saturation conditions. The other consideration is often referred to as 'mechanical minimum flow', which is that flow required to prevent mechanical damage. However, the criteria for specifying such a minimum flow are not clearly understood by all parties concerned. Also various factor and information for ...

2009-10-01

360

Molecular identification of blood source animals from black flies (Diptera: Simuliidae) collected in the alpine regions of Japan  

British Library Electronic Table of Contents (United Kingdom)

One of vector-borne avian protozoa, Leucocytozoon lovati, has been found in the Japanese rock ptarmigans (Lagopus mutus japonicus), the endangered bird species distributed in the alpine regions in Japan. Vector arthropod species of L. lovati has also been estimated as Simuliidae black flies distributed in the same habitat of the host bird, however, possible blood meals of the black flies were not identified yet. To reveal host animals of black flies, we estimated the blood resources by using molecular techniques. Black flies were collected at Mt. Chogatake, one of the alpine regions of Japan in which Japanese rock ptarmigans live in June 2005. The analyzed 144 specimens were morphologically identified into five species including Simulium japonicum (n?=?87), Prosimulium hirtipes (n?=?48), P...

2010-01-01

361

In vivo distribution and excretion studies and in vitro blood studies on the kinetics of lead-203 in beagle dogs  

International Nuclear Information System (INIS)

Studies on the kinetics of the distribution of lead-203 in body fluids have been carried out in vitro, and in animal studies using beagle dogs. In vitro, the distribution of carrier free lead-203 between plasma and cells of canine blood at 37"0C was measured after the addition of isotope. In animal studies, activity in plasma was measured for about 150 hours, and activity in blood cells, urine and feces measured for about 400 hours after exposure to lead-203. Linear compartmental models for distribution of the isotope are presented for both in vitro and in vivo experimental systems. The models contain compartments for both untransformed lead, for isotope added in saline or citric acid, and transformed lead, as obtained by lead-203 incubation in plasma.

362

Effects of various maillard reaction products on in vitro starch hydrolysis and blood glucose responses in mice  

British Library Electronic Table of Contents (United Kingdom)

Abstract This study investigated the effects of Maillard reaction products (MRPs) on in vitro starch hydrolysis, and in vivo blood glucose responses in mice. Four MRPs of various dextrose equivalents were prepared by heating a mixture of hydrolyzed rice starch and glycine at 200C for 4-min. The starch hydrolysis rates of gelatinized rice starch (GRS) decreased as the browning reaction of added MRPs increased. The hydrolysis kinetic constants of the GRS with 5% MRPs were relatively lower than that of GRS without MRPs. Blood glucose responses showed similar tendencies to the in vitro starch hydrolysis results. The activity of digestive enzymes was inhibited by the MRPs. The relative crystallinity of all MRPs (29.9-60.1%) appeared to have higher values than GRS (15.1%). The samples heated to ...

2011-01-01

363

Colocalization in vivo and association in vitro of perlecan and elastin  

British Library Electronic Table of Contents (United Kingdom)

We have colocalized elastin and fibrillin-1 with perlecan in extracellular matrix of tensional and weight-bearing connective tissues. Elastin and fibrillin-1 were identified as prominent components of paraspinal blood vessels, and posterior longitudinal ligament in the human fetal spine and outer annulus fibrosus of the fetal intervertebral disc. We also colocalized perlecan with a synovial elastic basal lamina, where the attached synovial cells were observed to produce perlecan. Elastin, fibrillin-1 and perlecan were co-localized in the intima and media of small blood vessels in the synovium and in human fetal paraspinal blood vessels. Elastic fibers were observed at the insertion point of the anterior cruciate ligament to bone in the ovine stifle joint where they colocalized with perleca...

2011-01-01

364

Analysis of cerebrospinal fluid from chronic fatigue syndrome patients for multiple human ubiquitous viruses and xenotropic murine leukemia-related virus  

British Library Electronic Table of Contents (United Kingdom)

Abstract Recent reports showed many patients with chronic fatigue syndrome (CFS) harbor a retrovirus, xenotropic murine leukemia-related virus (XMRV), in blood; other studies could not replicate this finding. A useful next step would be to examine cerebrospinal fluid, because in some patients CFS is thought to be a brain disorder. Finding a microbe in the central nervous system would have greater significance than in blood because of the integrity of the blood-brain barrier. We examined cerebrospinal fluid from 43 CFS patients using polymerase chain reaction techniques, but did not find XMRV or multiple other common viruses, suggesting that exploration of other causes or pathogenetic mechanisms is warranted. Ann Neurol 2011;

2011-01-01

365

Turbulent break-off flows  

Energy Technology Data Exchange (ETDEWEB)

Different calculated models are presented for turbulent break-off flows and their classification, reflecting the sequence of historical development. The study was done based on equations of viscous liquid of the Navier-Stokes type with development of special phenomenological models of turbulence which take into consideration real properties of the break-off flows based on simpler models of flow presented in the work. In order to calculate two-dimensional turbulent flows, a method of viscous-nonviscous interaction is used. It employs numerical solutions for nonviscous flow and integrated methods of calculating the dissipative region. This method can be extended for calculating the transonic break-off flows, and also break-off in an incompressible fluid when there is cavitation.

1982-01-01

366

Comparative study of three dimensional numerical simulations of particle dispersion in a turbulent air flow  

International Nuclear Information System (INIS)

This paper describes the study of particles' dispersion in an isotropic turbulent flow. The particle's motion and the turbulent flow characteristics are calculated independently. While the particles' displacement is computed by the author's code, the flow is simulated with a commercial code : PowerFLOW. The particles and the flow are coupled through the relative velocity component of the aerodynamic force. When the simulated flow is turbulent, a turbulence regeneration model is used in order to get the flow instantaneous velocity. Validation of the method is done by comparing the particles' dispersion obtained with experimental results from literature and with the results calculated by FLUENT. Good accordance is found between numerical studies and experimental results. However, comparison between results of PowerFLOW ...

2004-05-09

367

Visualization of liquid metal two-phase flow by a real time neutron radiography system  

Energy Technology Data Exchange (ETDEWEB)

In order to understand the detail transient two-phase flow structure, more advanced two-phase flow instrumentation is required. One advanced technique for flow visualization is real-time neutron radiography. Reconstruction method of visualized radiographic image of liquid metal two-phase flow generated by the real-time neutron radiography system is proposed in this paper. Image processing techniques for noise reduction and image enhancement are discussed in detail. (author).

1995-11-01

368

Visualization of liquid metal two-phase flow by a real time neutron radiography system  

International Nuclear Information System (INIS)

In order to understand the detail transient two-phase flow structure, more advanced two-phase flow instrumentation is required. One advanced technique for flow visualization is real-time neutron radiography. Reconstruction method of visualized radiographic image of liquid metal two-phase flow generated by the real-time neutron radiography system is proposed in this paper. Image processing techniques for noise reduction and image enhancement are discussed in detail. (author).

1995-01-01

369

Mixed convection flows in a channel with a vortex generator  

Science.gov (United States)

This paper presents a numerical investigation of laminar flows and heat transfer in a horizontal rectangular channel whose top and bottom plates have been punched out in the form of a delta wing. The flow structure with respect to the generation, transport, and stability of vortices in laminar horizontal channel flows with combined forced and free convection are reported. To include free convection, Boussinesq approximation of the buoyancy is used and the flow medium is treated as incompressible.

1989-01-01

370

Gas-liquid two-phase flow patterns in parallel channels for fuel cells  

Energy Technology Data Exchange (ETDEWEB)

Two-phase flow in horizontal parallel channels has been experimentally investigated under fuel cell related operating conditions. Pronounced hysteresis is observed in the pressure drop versus flow characteristic curve when starting from either flooded or dry conditions. When gas is introduced into channels initially filled with water (flooded initial condition), both gas and liquid tend to flow predominantly in one channel at low gas or liquid flow velocities. As the gas flow velocity increases, even distribution of gas and liquid flow in both channels is observed, accompanied with a sudden decrease in the pressure drop. On the other hand, even gas and liquid flow distribution between both channels is found at comparatively lower gas flow velocities when starting with dry-gas flow conditions with ...

2008-09-01

371

var gene transcription and PfEMP1 expression in the rosetting and cytoadhesive Plasmodium falciparum clone FCR3S1.2  

UK PubMed Central (United Kingdom)

BackgroundThe pathogenicity of Plasmodium falciparum is in part due to the ability of the parasitized red blood cell (pRBC) to adhere to intra-vascular host cell...Full Text Available

372

What Parents Should Know about Medical Radiation Safety in Interventional Radiology  

Science.gov (United States)

... Amount Background Radiation Blood vessel central line, PICC (peripherally inserted central catheter) or port placement, simple 0.4 mSv ...

373

Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis.  

UK PubMed Central (United Kingdom)

Vascular permeability factor (VPF) is an Mr 40-kD protein that has been purified from the conditioned medium of guinea pig line 10 tumor cells grown in vitro, and increases fluid permeability from blood...Full Text Available

1989-11-01

374

Transport into retina measured by short vascular perfusion in the rat.  

UK PubMed Central (United Kingdom)

1. The short duration cerebrovascular perfusion method for measuring permeability of the blood-brain barrier has been adapted to measuring transport into the retina. 2. The method has been characterized...Full Text Available

1993-10-01

375

Tight Blood Glucose Control Is Renoprotective in Critically Ill Patients  

UK PubMed Central (United Kingdom)

Two large, prospective, randomized, controlled trials have shown a beneficial effect of intensive insulin therapy (IIT) on the kidney function of critically ill patients. The data from these trials...Full Text Available

2008-03-01

376

The Blood-Brain Barrier and Microvascular Water Exchange in Alzheimer's Disease  

UK PubMed Central (United Kingdom)

Alzheimer's disease (AD) is the most common form of dementia in the elderly. Although traditionally considered a disease of neurofibrillary tangles and amyloid plaques, structural and functional changes...Full Text Available

2011-01-01

377

Temporal trends in hepatitis B and C infection in family blood donors from interior Sindh, Pakistan  

UK PubMed Central (United Kingdom)

BackgroundHepatitis B (HBV) and C (HCV) infections are a serious global and national public health problem. Earlier studies have reported increasing rates of hepatitis infection...Full Text Available

378

Telomeric DNA in normal and leukemic blood cells.  

UK PubMed Central (United Kingdom)

We studied telomeric DNA in leukemic cells as well as in normal T cells, B cells, monocytes, polymorphonuclear leukocytes, and bone marrow hematopoietic progenitor cells. No marked differences were...Full Text Available

1995-03-01

379

THE ROLE OF SALIVA IN TICK FEEDING  

UK PubMed Central (United Kingdom)

When attempting to feed on their hosts, ticks face the problem of host hemostasis (the vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or pain and thus...Full Text Available

380

Strategies for initial management of hypertension  

UK PubMed Central (United Kingdom)

High blood pressure (BP) is a major public health problem in India and its prevalence is rapidly increasing among urban and rural populations. Reducing systolic and diastolic BP can decrease cardiovascular...Full Text Available

2010-11-01

381

Spontaneous expression of the interleukin 2 receptor gene and presence of functional interleukin 2 receptors on T lymphocytes in the blood of individuals with active pulmonary sarcoidosis.  

UK PubMed Central (United Kingdom)

Current concepts of the pathogenesis of sarcoidosis suggest that the expanded numbers of activated T-helper/inducer cells at sites of disease activity result, at least in part, from their proliferation...Full Text Available

1988-09-01

382

Significance of arming, potentiating and blocking factors as correlates the tumour-host interaction in the hamster SV40 system.  

UK PubMed Central (United Kingdom)

The study of blocking factors requires in vitro assay of cell mediated immunity that parallels the in vivo response. By microcytotoxicity testing, progressor and immune peripheral blood lymphocytes...Full Text Available

1975-12-01

383

Sex and Death: The Effects of Innate Immune Factors on the Sexual Reproduction of Malaria Parasites  

UK PubMed Central (United Kingdom)

Malaria parasites must undergo a round of sexual reproduction in the blood meal of a mosquito vector to be transmitted between hosts. Developing a transmission-blocking intervention to prevent parasites...Full Text Available

2011-03-01

384

Serum hepcidin as a diagnostic test of iron deficiency in premenopausal female blood donors  

UK PubMed Central (United Kingdom)

BackgroundCurrently used indicators of iron status have limitations. Hepcidin, a key regulator of iron metabolism, is reduced in iron deficiency. We sought to determine the properties...Full Text Available

2011-08-01

385

Serratia odorifera biogroup 1 causing an invasive human infection.  

UK PubMed Central (United Kingdom)

Serratia odorifera biogroup 1 was isolated from the blood and urine of an alcoholic male with cirrhosis and signs of septic shock. The organism is rarely reported to occur in clinical specimens. This...Full Text Available

1988-06-01

386

Seasonal Protein Changes Support Rapid Energy Production in Hibernator Brainstem  

UK PubMed Central (United Kingdom)

During the torpor phase of mammalian hibernation when core body temperature is near 4°C, the autonomic system continues to maintain respiration, blood pressure and heartbeat despite...Full Text Available

2010-04-01

387

Review: Interventional radiology in peripheral vascular disease  

UK PubMed Central (United Kingdom)

Peripheral vascular diseases (PVD) are referred to as diseases affecting the blood vessels other than the heart and the brain. Interventional endovascular treatment whenever feasible has become the...Full Text Available

2008-05-01

388

Regulatory compliance | Mott MacDonald  

Wastenet

...broad range of experience in designing and building research and development laboratories for products such as vaccines, blood and sera, biological products, medical devices, solid dosage forms , highly potent products and cytotoxic material. We also have experience in a range of modular laboratories for TSE research, ...

389

Recent changes in the epidemiology and management of extended-spectrum ?-lactamase-producing Enterobacteriaceae  

UK PubMed Central (United Kingdom)

Since 2000, Escherichia coli producing CTX-M enzymes (especially CTX-M-15) have emerged worldwide as important causes of community-onset urinary tract and blood stream infections due...Full Text Available

390

Purification, characterization and binding interactions of the Chinese-cobra (Naja naja atra) serum antitoxic protein CSAP.  

UK PubMed Central (United Kingdom)

The characterization of the single-chain protein in Chinese-cobra (Naja naja atra) blood serum, which yields strong specific protection against the venom of the same snake, is reported. The protein,...Full Text Available

1993-07-15

391

Pseudomonas aeruginosa selective adherence to and entry into human endothelial cells.  

UK PubMed Central (United Kingdom)

The pathogenesis of Pseudomonas aeruginosa disseminated infections depends on bacterial interaction with blood vessels. We have hypothesized that in order to traverse the endothelial barrier, bacteria...Full Text Available

1994-12-01

392

Presence of preactivated T cells in hemodialyzed patients: their possible role in altered immunity.  

UK PubMed Central (United Kingdom)

Interleukin 2 (IL-2) and B-cell growth factors I and II (BCGF I and BCGF II) are lymphokines produced by T cells that play a major role in T- and B-cell cooperation. Peripheral blood lymphocytes from...Full Text Available

1986-10-01

393

Predictors of healthcare professionals' intention and behaviour to encourage physical activity in patients with cardiovascular risk factors  

UK PubMed Central (United Kingdom)

BackgroundHealthcare professionals can play a crucial role in optimizing the health status of patients with cardiovascular risk factors (abdominal obesity, high blood pressure, low...Full Text Available

394

Population genetic analysis of large sequence polymorphisms in Plasmodium falciparum blood-stage antigens  

UK PubMed Central (United Kingdom)

Plasmodium falciparum, the causative agent of human malaria, invades host erythrocytes using several proteins on the surface of the invasive merozoite, which have been proposed...Full Text Available

2010-03-01

395

Polymorphisms in the p53 gene in thyroid tumours and blood samples of children from areas in Belarus  

International Nuclear Information System (INIS)

We present changes in the p53 gene in a group of 70 thyroid tumours and 40 blood samples obtained from children from Belarus. Three thyroid tumours show a polymorphism in exon 6 (codon 213) and 5 tumours show a polymorphism in intron 6, 37 bp upstream to the 5'-end of exon 7. Only one patient has a mutation in exon 7 (codon 258) resulting in an amino acid substitution in the protein p53. The distribution of polymorphisms in the 40 blood samples was as follows: three patients had a polymorphism in exon 6 and two persons had a polymorphism in intron 6. One polymorphism in intron 6 was also found in the group of 30 healthy children from Belarus. The fact that the differences in the sequence in p53 found in the tumours was also seen in the blood of these patients demonstrates that they are polymorphisms not induced by radiation exposure. It is difficult to conclude, if the polymorphisms found by us could be associated with the ...

396

Phenotypic and functional immaturity of human umbilical cord blood T lymphocytes.  

UK PubMed Central (United Kingdom)

Successful implementation of bone marrow transplantation for hematopoietic reconstitution is limited by the lack of suitably HLA-matched donors and by the occurrence of graft-versus-host disease that...Full Text Available

1992-11-01

397

PROGRESS AND PROBLEMS IN THE APPLICATION OF FOCUSED ULTRASOUND FOR BLOOD-BRAIN BARRIER DISRUPTION  

UK PubMed Central (United Kingdom)

Advances in neuroscience have resulted in the development of new diagnostic and therapeutic agents for potential use in the central nervous system (CNS). However, the ability to deliver the...Full Text Available

2008-08-01

398

Oxidative Stress and Longevity in Okinawa: An Investigation of Blood Lipid Peroxidation and Tocopherol in Okinawan Centenarians  

UK PubMed Central (United Kingdom)

Background. The Free Radical Theory of Aging mechanistically links oxidative stress to aging. Okinawa has among the world's longest-lived populations but oxidative stress in this...Full Text Available

2010-01-01

399

NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1  

UK PubMed Central (United Kingdom)

Endothelial cells and mural cells (smooth muscle cells, pericytes, or fibroblasts) are known to communicate with one another. Their interactions not only serve to support fully functional blood...Full Text Available

2009-02-27

400

MRI features of epidural extramedullary hematopoiesis  

Energy Technology Data Exchange (ETDEWEB)

A case of {beta}-thalassemia intermedia with spinal cord compression due to extramedullary hematopoiesis, which was successfully treated by blood transfusion, is presented. Emphasis was made on the MRI appearance of extramedullary hematopoiesis on different pulse sequences. The theories that aimed to explain the involvement of the epidural space by extramedullary hematopoiesis are discussed.

2000-07-01

401

Loss of red cell chemokine scavenging promotes transfusion-related lung inflammation  

UK PubMed Central (United Kingdom)

Red cell transfusions are associated with the development of acute lung injury in the critically ill. Recent evidence suggests that storage induced alterations of the red blood cell (RBC) collectively...Full Text Available

2009-01-29

402

Lead and calcium distributions in blood, plasma, and milk of the lactating mouse  

Energy Technology Data Exchange (ETDEWEB)

Although it has been established that lead is transferred in milk from mother to suckling offspring, the physiological processes and parameters involved are not well understood. Single i.v. doses (0.2 mg/kg) or p.o. doses (2 mg/kg) of radiolabeled lead were administered to lactating and nonlactating female mice, and lead concentrations in blood, plasma, and milk were determined during a 21-day period. Large differences in lead elimination were observed between lactating and nonlactation mice. A significant fraction (25%) of the initial maternal dose (absorbed dose) was transferred to the suckling pups. The ratio of lead concentration in milk to lead concentration in plasma was found to be nearly constant over time. However, the milk-to-blood concentration ratios decreased during the same period. Furthermore, the concentration of lead in milk exceeded the plasma concentration by a factor of approximately 25, indicating that there is a ...

1980-01-01

403

Iron Overload, Hematopoietic Cell Transplantation, and Graft-versus-Host Disease  

UK PubMed Central (United Kingdom)

Many patients who undergo hematopoietic cell transplantation (HCT) present with anemia and have received red blood cell transfusions before HCT. As a result, iron overload is frequent and appears...Full Text Available

2009-10-01

404

Interictal Functional Connectivity of Human Epileptic Networks Assessed by Intracerebral EEG and BOLD Signal Fluctuations  

UK PubMed Central (United Kingdom)

In this study, we aimed to demonstrate whether spontaneous fluctuations in the blood oxygen level dependent (BOLD) signal derived from resting state functional magnetic resonance imaging (fMRI) reflect...Full Text Available

405

Increased Production and Expression of Tissue Thromboplastin-Like Procoagulant Activity In Vitro by Allogeneically Stimulated Human Leukocytes  

UK PubMed Central (United Kingdom)

Intravascular coagulation, thrombosis, and fibrin deposition often produce tissue damage in allogeneic inflammatory reactions such as allograft rejection. The mechanisms which initiate blood clotting...Full Text Available

1978-09-01

407

Impairment of brain endothelial glucose transporter by methamphetamine causes blood-brain barrier dysfunction  

UK PubMed Central (United Kingdom)

BackgroundMethamphetamine (METH), an addictive psycho-stimulant drug with euphoric effect is known to cause neurotoxicity due to oxidative stress, dopamine accumulation and glial...Full Text Available

408

Identification of CTX-M-14 Extended-Spectrum ?-Lactamase in Clinical Isolates of Shigella sonnei, Escherichia coli, and Klebsiella pneumoniae in Korea  

UK PubMed Central (United Kingdom)

CTX-M-14 β-lactamase was identified in a stool isolate of Shigella sonnei and in blood isolates of Escherichia coli (one isolate) and Klebsiella pneumoniae...Full Text Available

2001-10-01

409

Gingival crevicular fluid levels of clindamycin compared with its minimal inhibitory concentrations for periodontal bacteria.  

UK PubMed Central (United Kingdom)

Clindamycin concentrations in gingival crevicular fluid and in blood were determined over a 7-h period and were related to the minimal inhibitory concentrations of this agent for 340 bacterial strains...Full Text Available

1981-05-01

410

Genetic heterogeneity in human T-cell leukemia/lymphoma virus type II.  

UK PubMed Central (United Kingdom)

DNA from the peripheral blood mononuclear cells of 17 different individuals infected with human T-cell lymphoma/leukemia virus type II (HTLV-II) was successfully amplified by the polymerase chain reaction...Full Text Available

1993-03-01

411

Five year prospective study of plasma renin activity and blood pressure in patients with longstanding reflux nephropathy.  

UK PubMed Central (United Kingdom)

Eight of 100 normotensive children who had pyelonephritic scarring secondary to urinary infection and vesicoureteric reflux were found in an earlier study to have increased plasma renin activity (PRA)....Full Text Available

1987-07-01

412

Evaluation of cefoxitin nephrotoxicity in experimentally induced renal failure.  

UK PubMed Central (United Kingdom)

The nephrotoxicity of cefoxitin was studied in a rat model of impaired renal function. Two levels of renal impairment were produced: "moderate," with blood urea concentrations of 100 to 150 mg/100 ml...Full Text Available

1981-01-01

413

Evaluation of Systemic Markers Related To Anemia of Chronic Disease in the Peripheral Blood of Smokers and Non-Smokers with Chronic Periodontitis  

UK PubMed Central (United Kingdom)

ObjectivesThe aim of this study was to investigate the effect of cigarette smoking on clinical parameters and signs anemia of chronic disease in chronic periodontitis patients.Full Text Available

2008-04-01

414

Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes  

UK PubMed Central (United Kingdom)

Bitter orange (Citrus aurantium) extract is widely used in dietary supplements for weight management and sports performance. Its primary protoalkaloid is p-synephrine....Full Text Available

415

Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials  

UK PubMed Central (United Kingdom)

SummaryBackgroundPatients undergoing dialysis have a substantially increased risk of cardiovascular mortality and morbidity. Although several trials have shown the...Full Text Available

2009-03-21

416

Effect of lead on erythrocyte membranes.  

UK PubMed Central (United Kingdom)

The effect of blood lead on erythrocyte membrane proteins was studied in 28 workers from a scrap lead refining factory and in 18 controls working in railway construction. Sodium dodecyl sulphate-polyacrylamide...Full Text Available

1983-05-01

417

Effect of early bursectomy on germinal centre and immunoglobulin production in chickens.  

UK PubMed Central (United Kingdom)

Chickens were bursectomized in ovo on days 18, 19 or 20 of incubation or within 6 h of hatch and immunized at day 28 after hatch by an intravenous injection of sheep red blood cells (SRBC). The immune...Full Text Available

1977-11-01

418

Effect of Breast Milk Lead on Infant Blood Lead Levels at 1 Month of Age  

UK PubMed Central (United Kingdom)

Nursing infants may be exposed to lead from breast milk, but relatively few data exist with which to evaluate and quantify this relationship. This route of exposure constitutes a potential infant hazard...Full Text Available

2004-10-01

419

Donor deferral due to anemia: A tertiary care center-based study  

UK PubMed Central (United Kingdom)

Background:The minimum hemoglobin cutoff for blood donation in India is 12.5 gm% for both male and female donors and the minimum donation interval is 3 months. Donation...Full Text Available

2011-01-01

420

Detection of hepatitis B virus DNA among accepted blood donors in Nanjing, China  

UK PubMed Central (United Kingdom)

BackgroundPosttransfusion hepatitis B virus (HBV) infection still occurs although its incidence has been substantially reduced since the introduction of screening of hepatitis B...Full Text Available

421

Detection of Streptococcus mutans Genomic DNA in Human DNA Samples Extracted from Saliva and Blood  

UK PubMed Central (United Kingdom)

Caries is a multifactorial disease, and studies aiming to unravel the factors modulating its etiology must consider all known predisposing factors. One major factor is bacterial colonization,...Full Text Available

2011-01-01

422

Deletion of the Plasmodium falciparum Merozoite Surface Protein 7 Gene Impairs Parasite Invasion of Erythrocytes?  

UK PubMed Central (United Kingdom)

Merozoite surface proteins have been implicated in the initial attachment to the host red blood cell membrane that begins the process of invasion, an important step in the life cycle of the malaria...Full Text Available

2008-12-01

423

D2-40, Podoplanin, and CD31 as a Prognostic Predictor in Invasive Ductal Carcinomas of the Breast  

UK PubMed Central (United Kingdom)

PurposeDistant metastasis and recurrence are major prognostic factors associated with breast cancer. Both lymphovascular invasion (LVI) and blood vessel invasion (BVI) are important...Full Text Available

2011-06-01

424

Cross-sectional measures and modelled estimates of blood alcohol levels in UK nightlife and their relationships with drinking behaviours and observed signs of inebriation  

UK PubMed Central (United Kingdom)

BackgroundManagement of nightlife in UK cities focuses on creating safe places for individuals to drink. Little is known about intoxication levels as measuring total alcohol consumption...Full Text Available

425

Convective burn from use of hairdryer for heel warming prior to the heel prick test - a case report  

UK PubMed Central (United Kingdom)

BackgroundBlood sampling through heel lancing is the most common invasive painful procedure performed on newborn infants.Case PresentationWe report...Full Text Available

426

Convection-enhanced Delivery of Free Gadolinium with the Recombinant Immunotoxin MR1-1  

UK PubMed Central (United Kingdom)

PurposeA major obstacle in glioblastoma (GBM) therapy is the restrictive nature of the blood-brain barrier (BBB). Convection-enhanced delivery (CED) is a novel method...Full Text Available

2010-05-01

427

Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria  

UK PubMed Central (United Kingdom)

There is growing epidemiological and molecular evidence that ABO blood group affects host susceptibility to severe Plasmodium falciparum infection. The high frequency of common...Full Text Available

2008-02-15

428

Clinical review: Patency of the circuit in continuous renal replacement therapy  

UK PubMed Central (United Kingdom)

Premature circuit clotting is a major problem in daily practice of continuous renal replacement therapy (CRRT), increasing blood loss, workload, and costs. Early clotting is related to bioincompatibility,...Full Text Available

2007-01-01

429

Chromium and manganese levels in biological samples of normal and night blindness children of age groups (3-7) and (8-12) years.  

Science.gov (United States)

This study was designed to compare the levels of chromium (Cr) and manganese (Mn) in scalp hair, blood, and urine of night blindness in children age ranged (3-7) and (8-12) years of both genders, comparing them to sex- and age-matched controls. A microwave-assisted wet acid digestion procedure, was developed as a sample pretreatment, for the determination of Cr and Mn in biological samples of night blindness children. The proposed method was validated by using conventional wet digestion and certified reference samples of hair, blood and urine. The digests of all biological samples were analyzed for Cr and Mn by electrothermal atomic absorption spectrometry. The results indicated significantly higher levels of Cr, whilst low level of Mn in the biological samples (blood and scalp hair) of male and female night blindness children, compared with control subjects of both genders. These data present guidance to clinicians and ...

2010-09-21

430

Characterization of an oligopeptide chemoattractant receptor on human blood monocytes using a new radioligand  

Energy Technology Data Exchange (ETDEWEB)

The study of chemoattractant receptors on human monocytes had been limited by the lack of a radioligand suitable for use with the small numbers of cells routinely available from human donors. A new synthetic oligopeptide radioligand f(/sup 35/S)Met-leu-phe, with a higher specific radioactivity than was available with the tritiated compound, was used to characterize a chemoattractant receptor on freshly isolated human blood monocytes. These cells bind f(/sup 35/)met-leu-phe with a dissociation constant (KD) of 30.2 +/- 5.6 nM and contain 84,000 +/- 11,300 receptors per cell. f(/sup 35/)met-leu-phe does not bind specifically to blood lymphocytes. The specificity of the oligopeptide receptor on monocytes is indistinguishable from the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes. Using f(/sup 35/)met-leu-phe, it will now be feasible to study the chemotactic peptide receptor on small numbers of partially purified ...

1984-03-01

431

Characteristics relevant to cardiovascular disease among adults of African and Indian origin in Guyana  

UK PubMed Central (United Kingdom)

Characteristics relevant to cardiovascular disease, including anthropometry, arterial blood pressure, serum cholesterol levels, chest radiography and electrocardiography, were investigated in a survey...Full Text Available

1970-01-01

432

Calcium - blood test: MedlinePlus Medical Encyclopedia  

Science.gov (United States)

Names Ca+2; Serum calcium; Ca++ References Wysolmerski JJ, Insogna KL. The parathyroid glands, hypercalcemia, and hypocalcemia. In: Goldman L, Ausiello D, eds. Cecil...

2011-08-30

433

Breakdown of the Blood-Brain Barrier during Tick-Borne Encephalitis in Mice Is Not Dependent on CD8+ T-Cells  

UK PubMed Central (United Kingdom)

Tick-borne encephalitis (TBE) virus causes severe encephalitis with serious sequelae in humans. The disease is characterized by fever and debilitating encephalitis that can progress to chronic illness...Full Text Available

434

Automation in urinalysis: evaluation of three urine test strip analysers  

UK PubMed Central (United Kingdom)

A clinical laboratory evaluation was conducted on the Clinitek Auto 2000, the Super Aution Analyzer and the Urotron RL9 for the determination of glucose, protein, pH, blood, ketone-bodies and bilirubin....Full Text Available

1988-01-01

435

Association of Thyroid Hormone Concentrations with Levels of Organochlorine Compounds in Cord Blood of Neonates  

UK PubMed Central (United Kingdom)

BackgroundThyroid hormones are important regulators of brain development. During critical periods of development, even transient disorders in thyroid hormone availability may lead...Full Text Available

2007-12-01

436

Arsenic-Associated Oxidative Stress, Inflammation, and Immune Disruption in Human Placenta and Cord Blood  

UK PubMed Central (United Kingdom)

BackgroundArsenic (As) exposure during pregnancy induces oxidative stress and increases the risk of fetal loss and low birth weight.ObjectivesIn...Full Text Available

2011-02-01

437

Antisense imaging of gene expression in the brain in vivo  

UK PubMed Central (United Kingdom)

Antisense radiopharmaceuticals could be used to image gene expression in the brain in vivo, should these polar molecules be made transportable through the blood–brain barrier....Full Text Available

2000-12-19

438

Antihemostatic molecules from saliva of blood-feeding arthropods.  

Science.gov (United States)

The ability to feed on vertebrate blood has evolved many times in various arthropod clades. Each time this trait evolves, novel solutions to the problem posed by vertebrate hemostasis are generated. Consequently, saliva of blood-feeding arthropods has proven to be a rich source of antihemostatic molecules. Vasodilators include nitrophorins (nitric oxide storage and transport heme proteins), a variety of peptides that mimic endogenous vasodilatory neuropeptides, and proteins that catabolize or sequester endogenous vasoconstrictors. A variety of platelet aggregation inhibitors antagonize platelet responses to wound-generated signals, including ADP, thrombin, and collagen. Anticoagulants disrupt elements of both the intrinsic and extrinsic pathways. Molecular approaches (termed 'sialomics') to characterize the full inventory of mRNAs transcribed in salivary glands have revealed a surprising level of complexity within a single species. Multiple ...

2005-01-01

439

An 802.11 Wireless Blood Pulse-Oximetry System for Medical Response to Disasters  

UK PubMed Central (United Kingdom)

In a mass casualty situation, medical personnel at the disaster site and other field treatment settings may need to monitor the vital signs of hundreds of seriously injured patients with minimal staffing....Full Text Available

2005-01-01

440

Addressing the Question of the Effect of RBC Storage on Clinical Outcomes: The Red Cell Storage Duration Study (RECESS) (Section 7)  

UK PubMed Central (United Kingdom)

The question of whether storage of red blood cells (RBCs) alters their capacity to deliver oxygen and affects patient outcomes remains in a state of clinical equipoise. Studies of the changes...Full Text Available

2010-08-01

441

Adaptive Thresholding for Improving Sensitivity in Single-Trial Simultaneous EEG/fMRI  

UK PubMed Central (United Kingdom)

A common approach used to fuse simultaneously recorded EEG and fMRI is to correlate trial-by-trial variability in the EEG, or variability of components derived therefrom, with the blood oxygenation...Full Text Available

442

Activation of peripheral blood mononuclear cells in bronchoalveolar lavage fluid from patients with sarcoidosis: visualisation of single cell activation products.  

UK PubMed Central (United Kingdom)

BACKGROUND--Interstitial lung diseases are characterised by the recruitment of mononuclear cells to disease sites where maturation occurs and activation products, including lysozyme (LZM), are released....Full Text Available

1994-11-01

443

Accumulation of Plasmodium berghei-Infected Red Blood Cells in the Brain Is Crucial for the Development of Cerebral Malaria in Mice?  

UK PubMed Central (United Kingdom)

Cerebral malaria is the most severe complication of human infection with Plasmodium falciparum. It was shown that Plasmodium berghei ANKA-induced cerebral malaria was...Full Text Available

2010-09-01

444

A study of membrane protein defects and alpha hemoglobin chains of red blood cells in human beta thalassemia  

International Nuclear Information System (INIS)

The soluble pool of alpha hemoglobin chains present in blood or bone marrow cells was measured with a new affinity method using a specific probe, beta A hemoglobin chain labeled with ["3H]N-ethylmaleimide. This pool of soluble alpha chains was 0.067 #+-# 0.017% of hemoglobin in blood of normal adult, 0.11 #+-# 0.03% in heterozygous beta thalassemia and ranged from 0.26 to 1.30% in homozygous beta thalassemia intermedia. This elevated pool of soluble alpha chains observed in human beta thalassemia intermedia decreased 33-fold from a value of 10% of total hemoglobin in bone marrow cells to 0.3% in the most dense red blood cells. The amount of insoluble alpha chains was measured by using the polyacrylamide gel electrophoresis in urea and Triton X-100. In beta thalassemia intermedia the amount of insoluble alpha chains was correlated with the decreased spectrin content of red cell membrane and was associated with a decrease in ...

445

A polyacetylene compound from herbal medicine regulates genes associated with thrombosis in endothelial cells  

UK PubMed Central (United Kingdom)

From Toki-shakuyaku-san, an herbal formulation for “cleansing stagnated blood,” a key gene regulatory compound was purified and identified through a screening based on DNA microarray...Full Text Available

2007-12-15

446

A mathematical/physiological model of parathyroid hormone secretion in response to blood-ionized calcium lowering in vivo.  

DEFF Research Database (Denmark)

The aim of the present study was to test a mathematical model of the biochemical processes in the parathyroid glands responsible for the secretion of parathyroid hormone resulting from extracellular calcium reduction. A double exponential curve described the parathyroid hormone secretion induced by rapid lowering of blood-ionized calcium in humans with normal as well as abnormal parathyroid tissue. Our data show that it was possible to establish a simple mathematical model of the parathyroid hormone response to blood-ionized calcium lowering, sufficient to fit experimental data obtained from patients with abnormal and normal parathyroid tissue. The fitted parameters showed no significant differences between patients with insulin-dependent diabetes mellitus and controls. In primary hyperparathyroidism, the parathyroid hormone production and steady-state transport across the cell membrane were increased, probably due to the larger amount of ...

1997-01-01

447

A biological standard for measurement of blood coagulation factor VIII activity  

UK PubMed Central (United Kingdom)

Because of the instability of Factor VIII (antihaemophilic factor) in plasma in vitro, and since evidence has accumulated that the level of activity varies significantly between samples...Full Text Available

1971-01-01

448

29 CFR 1926.62 - Lead.  

Science.gov (United States)

...retardation, behavioral disorders or...blood. (3) Health protection goals...protecting your health. You are strongly...an independent analysis. The two...impairment of health. One of...although most cases of lead-induced...in the form of behavioral...

2010-07-01

449

Placental transfer of 14C-hexoprenaline. [Rabbits  

Energy Technology Data Exchange (ETDEWEB)

The placental transfer of a single intravenous injection of 14C-hexoprenaline was studied in eight pregnant New Zealand white rabbits. Maternal and fetal blood was sampled intermittently for 60 minutes after the injection. An initial rapid decrease in the levels of 14C-hexoprenaline in maternal blood was followed by a second slower phase, whereas fetal levels remained insignificant. The conclusion, therefore, is that the rapid improvement in fetal heart rate after the administration of a single maternal intravenous injection of hexoprenaline in the treatment of fetal distress is due to the action on the uterus and/or on maternal cardiovascular function, and not to direct stimulation of the fetus.

1982-02-01

450

Placental transfer of 14C-hexoprenaline  

International Nuclear Information System (INIS)

The placental transfer of a single intravenous injection of 14C-hexoprenaline was studied in eight pregnant New Zealand white rabbits. Maternal and fetal blood was sampled intermittently for 60 minutes after the injection. An initial rapid decrease in the levels of 14C-hexoprenaline in maternal blood was followed by a second slower phase, whereas fetal levels remained insignificant. The conclusion, therefore, is that the rapid improvement in fetal heart rate after the administration of a single maternal intravenous injection of hexoprenaline in the treatment of fetal distress is due to the action on the uterus and/or on maternal cardiovascular function, and not to direct stimulation of the fetus.

1982-02-01

451

Action of radiation on biosynthesis of hemoglobin and some of its electrophoretic fractions  

International Nuclear Information System (INIS)

Biosynthesis of hemoglobin and some of its electrophoretic fractions in red cells of peripheral blood and spleen of irradiated (650 R) rats has been studied. Hemoglobin synthesis is found to be most drastically inhibited in the first and second fractions on the first and eighth days after irradiation and in the fifth and sixth fractions on the eighth day (less expressed). The synthesis is restored on the twelfth day, the process under study proceeding more slowly in the above-mentioned fractions than in others. In the course of radiation sickness, the biosynthesis of certain hemoglobin fractions varies differently in the hemoglobin-synthesizing cells of peripheral blood than in the cells of spleenic erythroid series.

452

In vivo distribution and excretion studies and in vitro blood studies on the kinetics of lead-203 in beagle dogs. [Thesis  

Energy Technology Data Exchange (ETDEWEB)

The distribution of carrier free lead-203 between plasma and cells of canine blood in vitro was measured. Activity in the plasma decreased to less than 5% of the initial blood activity during the first 15 min and then exponentially with a half time of 160 min. Incubation in cell free plasma before addition to whole blood transformed the isotope, decreasing the amount subsequently associated with cells. In animal studies, activity was measured in plasma, blood cells, urine, and feces after exposure to lead-203. In one group, the animals were exposed by intravenous injection of dilute citric acid solutions of isotope. In a second group, carrier free isotope which had been transformed by incubation in plasma was injected intravenously. The kinetics of the distribution of the isotope differed between the two experimental groups. After injection of the transformed lead, the lead-203 content of the ...

1980-01-01

453

Five year prospective study of plasma renin activity and blood pressure in patients with longstanding reflux nephropathy.  

Science.gov (United States)

Eight of 100 normotensive children who had pyelonephritic scarring secondary to urinary infection and vesicoureteric reflux were found in an earlier study to have increased plasma renin activity (PRA). Because the risk of these patients becoming hypertensive is between 10% and 20% and because renin activity may play a part in the pathogenesis of the hypertension, PRA and blood pressure were studied in 98 of the original group after five years of follow up. Two patients could not be traced, and other factors that might influence blood pressure or PRA led us to exclude 13 others, 10 of whom were girls taking oral hormonal contraceptives. Increased PRA was found in 11 of the remaining 85 patients but not in five of the eight patients with increased PRA in the first study. Of eight children identified as hypertensive in the follow up study, only three had had increased PRA five years previously. In normal children PRA decreases with age. In the ...

1987-07-01

454

de Haas--van Alphen effect and Fermi surface of lutetium  

International Nuclear Information System (INIS)

We report de Haas--van Alphen measurements of the Fermi surface of lutetium at temperatures down to 0.3 K and in fields up to 150 kG in the (1010) and (1120) planes. Lutetium, having a filled 4f shell, serves as a nonmagnetic prototype of the structurally similar (hcp), trivalent, heavy rare-earth elements from Gd to Tm. The fact that no complete frequency branches were observed indicates that there are no closed pieces of the Fermi surface. We observed all but one orbit predicted by relativistic augmented-plane-wave calculations of Keeton and Loucks and by recent spin-orbit--linearized-augmented-plane-wave calculations of Tibbetts and Harmon. The data support a geometry similar to that of yttrium, and in good qualitative agreement with energy-band theory.

455

The high-density regime of kinetic-dominated loop quantum cosmology  

CERN Document Server

We study the dynamics of states perturbatively expanded about a harmonic system of loop quantum cosmology, exhibiting a bounce. In particular, the evolution equations for the first and second order moments of the system are analyzed. These moments back-react on the trajectories of the expectation values of the state and hence alter the energy density at the bounce. This analysis is performed for isotropic loop quantum cosmology coupled to a scalar field with a small but non-zero constant potential, hence in a regime in which the kinetic energy of matter dominates. Analytic restrictions on the existence of dynamical coherent states and the meaning of semi-classicality within these systems are discussed. A numerical investigation of the trajectories of states that remain semi-classical across the bounce demonstrates that, at least for such states, the bounce persists and that its properties are similar to the standard case, in which the moments of the states are ...

2010-01-01

456

The electron cyclotron absorption diagnostic for the JET pumped divertor plasma  

International Nuclear Information System (INIS)

We present the design of a diagnostic system to measure electron cyclotron absorption at the second harmonic E-mode resonance in the JET pumped divertor plasma. The diagnostic will measure transmission as a function of frequency along one or more sightlines from which the spatial profile of the n_eT_e product will be deduced. The divertor is briefly described, and the electron cyclotron resonance physics relevant to this measurement is reviewed. The problems of measuring transmission using an oversized transmission system are discussed and the chosen measurement technique, a swept frequency interferometer using a coherent radiation source, is described. A prototype of the instrument has been assembled to test the measurement technique. Some data demonstrating the instrument's characteristics are presented. The nonresonant losses, which may affect the interpretation of the measurement, are also discussed. (orig.).

1993-03-01

457

Synchrotron radiation from electron beams in plasma-focusing channels.  

Science.gov (United States)

Spontaneous radiation emitted from relativistic electrons undergoing betatron motion in a plasma-focusing channel is analyzed, and applications to plasma wake-field accelerator experiments and to the ion-channel laser (ICL) are discussed. Important similarities and differences between a free electron laser (FEL) and an ICL are delineated. It is shown that the frequency of spontaneous radiation is a strong function of the betatron strength parameter a(beta), which plays a role similar to that of the wiggler strength parameter in a conventional FEL. For a(beta) > or approximately 1, radiation is emitted in numerous harmonics. Furthermore, a(beta) is proportional to the amplitude of the betatron orbit, which varies for every electron in the beam. The radiation spectrum emitted from an electron beam is calculated by averaging the single-electron spectrum over the electron distribution. This leads to a frequency broadening of the radiation spectrum, which places ...

2002-05-20

458

Serial Intravascular Ultrasound Analysis of the Impact of Myocardial Bridge on Neointimal Proliferation After Coronary Stenting in Patients with Acute Myocardial Infarction  

British Library Electronic Table of Contents (United Kingdom)

Background: Mechanisms underlying the association between myocardial bridge (MB)-stenting and in-stent restenosis (ISR) are still unclear. Objective: To assess the impact of MB on ISR using intravascular ultrasound (IVUS). Methods: In the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial, 100 left anterior descending artery (LAD) culprit lesions (79 treated with paclitaxel-eluting stents [PES] and 21 treated with bare metal stents) were imaged with serial IVUS immediately postprocedure and at 13 months. Results: At baseline the LAD stent extended into the MB segment beyond the culprit lesion in seven patients (MB-stent group). In the remaining 93 patients the LAD stent was implanted only in the culprit lesion without extending into t...

2010-01-01

459

Perturbations of Schwarzschild Black Holes in Chern-Simons Modified Gravity  

CERN Document Server

We study perturbations of a Schwarzschild black hole in Chern-Simons modified gravity. We begin by showing that Birkhoff's theorem holds for a wide family of Chern-Simons coupling functions, a scalar field present in the theory that controls the strength of the Chern-Simons correction to the Einstein-Hilbert action. After decomposing the perturbations in spherical harmonics, we study the linearized modified field equations and find that axial and polar modes are coupled, in contrast to general relativity. The divergence of the modified equations leads to the Pontryagin constraint, which forces the vanishing of the Cunningham-Price-Moncrief master function associated with axial modes. We analyze the structure of these equations and find that the appearance of the Pontryagin constraint yields an overconstrained system that does not allow for generic black hole oscillations. We illustrate this situation by studying the case characterized by a canonical choice of the ...

2007-01-01

460

Los Alamos Advanced Free-Electron Laser  

Energy Technology Data Exchange (ETDEWEB)

At Los Alamos, we are building a free-electron laser (FEL) for industrial, medical, and research applications. This FEL, which will incorporate many of the new technologies developed over the last decade, will be compact in size, robust, and user-friendly. Electrons produced by a photocathode will be accelerated to 20 MeV by a high-brightness accelerator and transported using permanent-magnet quadrupoles and dipoles. They will form an electron beam with an excellent instantaneous beam quality of 10 {pi} mm mrad in transverse emittance and 0.3% in energy spread at a peak current up to 300 A. Including operation at higher harmonics, the laser wavelength extends form 3.7 {mu}m to 0.4 {mu}m. In this paper, we will describe the project and the programs to date. 10 refs., 10 figs., 1 tab.

1991-01-01

461

Locally resonant acoustic metamaterials with 2D anisotropic effective mass density  

British Library Electronic Table of Contents (United Kingdom)

A two-dimensional (2D) lattice model with anisotropic resonant microstructures is found to provide an anisotropic band gap structure. A 2D continuum with anisotropic effective mass density is introduced to represent this lattice system. Two methods are proposed to derive the equivalent continuum. In the first method, the effective mass density of the equivalent continuum is obtained by matching the dispersion relations for harmonic waves propagating in the principal directions. The second approach employs an approximate estimation of the effective mass density by volume-averaging an effective mass that represents the resonant microstructure. For both equivalent continuum models, the effective mass density is frequency-dependent and may become negative in certain frequency ranges. Subsequen...

2011-01-01

462

Language and Music in the Musician Brain  

British Library Electronic Table of Contents (United Kingdom)

Abstract Results of numerous experiments conducted over the past 15-years by using behavioural as well as brain imaging methods have shown that musical expertise influences brain anatomy, brain functions and behaviour. The musician- brain is thus considered as a very good model of brain plasticity. Moreover, many results have demonstrated that musical expertise not only impacts on music processing but also on several aspects of speech processing including lexical pitch, sentence intonation and the metric structure of words. Conversely, recent results indicated that linguistic expertise with tone or quantity languages such as Mandarin Chinese, Thai, Finnish and Japanese, influences the processing of harmonic tones and musical intervals. We discuss possible interpretations of these findings ...

2011-01-01

463

Infrared (IR) vs x-ray power generation in the SLAC Linac Coherent Light Source (LCLS)  

Energy Technology Data Exchange (ETDEWEB)

The LCLS, a Free-Electron Laser (FEL) designed for operation at a first harmonic energy of 300 eV ({lambda} {congruent} 40{Angstrom}) in the Self-Amplified Spontaneous Emission (SASE) regime, will utilize electron bunches compressed down to durations of <0.5ps, or lengths of <150 {mu}. It is natural to inquire whether coherent radiation of this (and longer) wavelength will constitute a significant component of the total coherent output of the FEL. In this paper a determination of a simple upper bound on the IR that can be generated by the compressed bunches is outlines. Under the assumed operating parameters of the LCLS undulator, it is shown that that IR component of the coherent output should be strongly dominated by the x-ray component.

1993-05-01

464

High Tc superconducting magnetic multivibrators for fluxgate magnetic-field sensors  

Science.gov (United States)

Sensitive and quick-response nonlinear inductance characteristics are found for high Tc superconducting (YBa/sub 2/Cu/sub 3/O/sub 7-chi/) disk cores at 77K in which soft magnetic BH hysteresis loops are observed. Various quick response magnetic devices such as modulators, amplifiers and sensors are built using these cores. The magnetizing frequency can be set to more than 20 MHz, which is difficult for conventional ferromagnetic bulk materials such as Permalloy amorphous alloys and ferrite. New quick-response fluxgate type magnetic-field sensors are made using ac and dc voltage sources. The former is used for second-harmonic type sensors, while the latter is for voltage-output multivibrator type sensors. Stable and quick-response sensor characteristics were obtained for two-core type multivibrators.

1989-09-01

465

Gravity-wave insights to Bianchi type-IX universes  

Energy Technology Data Exchange (ETDEWEB)

Every Bianchi type-IX universe can be interpreted as a closed Friedmann universe on which is superimposed circularly polarized gravitational waves with the longest wavelength that will fit into a closed universe. In this paper, I give a new derivation of this result based on the concept of homogeneous tensor fields on the three-sphere. Every homogeneous symmetric traceless tensor field is shown to be a longest-wavelength three-sphere harmonic. Contrary to previous authors, I show that the wavelength of these gravitational waves is one-half the circumference of the universe. In order to maintain homogeneity, the gravitational waves must all have the same polarization. There are five longest-wavelength modes for each polarization. This interpretation is an {ital exact} description that is valid for every Bianchi type-IX universe---it is in no way limited to first-order perturbations of a Friedmann universe.

1991-10-15

466

Frequency mixing crystal  

Energy Technology Data Exchange (ETDEWEB)

In a laser system for converting infrared laser light waves to visible light comprising a source of infrared laser light waves and means of harmoic generation associated therewith for production of light waves at integral multiples of the frequency of the original wave, the improvement of said means of harmonic generation comprising a crystal having the chemical formula X.sub.2 Y(NO.sub.3).sub.5 .multidot.2 nZ.sub.2 o wherein X is selected from the group consisting of Li, Na, K, Rb, Cs, and Tl; Y is selected from the group consisting of Sc, Y, La, Ce, Nd, Pr, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Al, Ga, and In; Z is selected from the group consisting of H and D; and n ranges from 0 to 4.

1992-01-01

467

Free-electron laser driven by the LBNL laser-plasma accelerator  

Energy Technology Data Exchange (ETDEWEB)

A design of a compact free-electron laser (FEL), generating ultra-fast, high-peak flux, XUV pulses is presented. The FEL is driven by ahigh-current, 0.5 GeV electron beam from the Lawrence Berkeley National Laboratory (LBNL) laser-plasma accelerator, whose active acceleration length is only a few centimeters. The proposed ultra-fast source (~;;10 fs) would be intrinsically temporally synchronized to the drive laser pulse, enabling pump-probe studies in ultra-fast science. Owing to the high current (>10 kA) of the laser-plasma-accelerated electron beams, saturated output fluxes are potentially greater than 10^13 photons/pulse. Devices based both on self-amplified spontaneous emission and high-harmonic generated input seeds, to reduce undulator length and fluctuations, are considered.

2008-08-04

468

Electron cyclotron current drive at {omega} approx. = {omega}{sub c} with X-mode launched from the low field side  

Energy Technology Data Exchange (ETDEWEB)

The electron cyclotron resonance layer in a tokamak, {omega}={omega}{sub c}(r), is not accessible by the extraordinary wave from the low field side, because it is shielded by a cutoff layer. However, a X-mode launched with a nonzero toroidal angle propagates at the cutoff parallel to the magnetic field and has a circular polarization. Therefore it can already at the cutoff layer interact efficiency with electrons via the Doppler shifted resonance. The driven current can be substantially higher than that driven by the second harmonic X-mode. The applicability of this current drive scheme is limited to rather low values of {omega}{sub p}{sup 2}/{omega}{sub c}{sup 2}, but may be of interest for high magnetic field devices. (author)

2000-02-01

469

Effects of velocity-dependent force on the magnetic form factors of odd-Z  

International Nuclear Information System (INIS)

We investigate the effects of the velocity-dependent force on the magnetic form factors and magnetic moments of odd-Z nuclei. The form factors are calculated with the harmonic-oscillator wavefunctions. It is found that the contributions of the velocity-dependent force manifest themselves in the very large momentum transfer region (q?4 fm-1). In the low and medium q region the contributions of the velocity-dependent force are very small compared with those without this force. However, in the high-q region the contributions of the velocity-dependent force are larger than the normal form factors. The diffraction structures beyond the existing experimental data are found after the contributions of the velocity-dependent force are included. The formula of the correction to the single particle magnetic moment due to the velocity-dependent force is reproduced exactly in the long-wavelength limit (q=0) of the M1 form factor. (authors)

2008-03-01

470

Double plasma mirror for ultrahigh temporal contrast ultra-intense laser pulses  

International Nuclear Information System (INIS)

We present and characterize a very efficient optical device that employs the plasma mirror technique to increase the contrast of high-power laser systems. Contrast improvements higher than 104 with 50% transmission are shown to be routinely achieved on a typical 10 TW laser system when the pulse is reflected on two consecutive plasma mirrors. Used at the end of the laser system, this double plasma mirror preserves the spatial profile of the initial beam, is unaffected by shot-to-shot fluctuations, and is suitable for most high peak power laser systems. We use the generation of high-order harmonics as an effective test for the contrast improvement produced by the double plasma mirrors. (authors)

471

Couple stress fluid improve rub-impact rotor-bearing system - Nonlinear dynamic analysis  

British Library Electronic Table of Contents (United Kingdom)

This study performs a dynamic analysis of the rub-impact rotor supported by two couple stress fluid film journal bearings. The strong nonlinear couple stress fluid film force, nonlinear rub-impact force and nonlinear suspension (hard spring) are presented and coupled together in this study. The displacements in the horizontal and vertical directions are considered for various non-dimensional speed ratios. The numerical results show that the dynamic behaviors of the system vary with the dimensionless speed ratios, the dimensionless unbalance parameters and the dimensionless parameter, l*. Inclusive of the periodic, sub-harmonic, quasi-periodic and chaotic motions are found in this analysis. The results of this study contribute to a further understanding of the nonlinear dynamics of a rotor-...

2010-01-01

472

Construction of the maximal solution of Backus? problem in geodesy and geomagnetism  

British Library Electronic Table of Contents (United Kingdom)

The (simplified) Backus? Problem (BP) consists in finding a harmonic function u on the domain exterior to the three dimensional unit sphere S, such that u tends to zero at infinity and the norm of the gradient of u takes prescribed values g on S. Except for a change of sign, the solution is not unique in general. However, there is uniqueness of solutions in the class of functions with the additional property that the radial component of the gradient of u on S is nonpositive. This is the geodetically relevant case. If a solution u with this property exists, then u is the maximal solution of the problem (and -u the minimal one). In this paper we propose a method of successive approximations to get this particular solution of BP and prove the convergence for functions g close to a constant fu...

2011-01-01

473

Chatter resistance of non-uniform turning bars with attached dynamic absorbers—Analytical approach  

British Library Electronic Table of Contents (United Kingdom)

Forced harmonic vibration of a non-uniform elastic beam with attached dynamic vibration absorbers (DVA) is studied. Analytical approximation of the solution is obtained by the functional perturbation method (FPM). The problem has application to cutting tools operations where the resistance of the tool holder against regenerative chatter can be enhanced by optimizing the real part of the frequency response function (FRF). A test case of a beam with step-like heterogeneity and single DVA at the tip shows that the FPM solution is very accurate for up to ?40 percent deviation in both stiffness and mass density. Using the analytical results and Sims approach, optimal DVA tuning is found for each set of beam heterogeneity parameters by solving a set of nonlinear algebraic equations numer...

2010-01-01

474

Atomic density functions: atomic physics calculations analyzed with methods from quantum chemistry  

CERN Document Server

This contribution reviews a selection of findings on atomic density functions and discusses ways for reading chemical information from them. First an expression for the density function for atoms in the multi-configuration Hartree--Fock scheme is established. The spherical harmonic content of the density function and ways to restore the spherical symmetry in a general open-shell case are treated. The evaluation of the density function is illustrated in a few examples. In the second part of the paper, atomic density functions are analyzed using quantum similarity measures. The comparison of atomic density functions is shown to be useful to obtain physical and chemical information. Finally, concepts from information theory are introduced and adopted for the comparison of density functions. In particular, based on the Kullback--Leibler form, a functional is constructed that reveals the periodicity in Mendeleev's table. Finally a quantum similarity measure is ...

2011-01-01

475

A unified framework for biological evolution and stochastic quantization  

CERN Document Server

We investigate the profound relation between the equations of biological evolution and quantum mechanics by writing a biologically inspired equation for the stochastic dynamics of an ensemble of particles. Interesting behavior is observed which is related to a new type of stochastic quantization. We find that the probability distribution of the ensemble of particles can be decomposed into eigenfunctions associated to a discrete spectrum of eigenvalues. In absence of interactions between the particles, the out-of-equilibrium dynamics asymptotically relaxes towards the fundamental state. This phenomenon can be related with the Fisher theorem in biology. On the contrary, in presence of scattering processes the evolution reaches a steady state in which the distribution of the ensemble of particles is characterized by a Bose-Einstein statistics. In order to show a concrete example of this stochastic quantization we have solved explicitly the case in which the potential energy has the ...

2010-01-01

476

The effect of flow-hole structure and water chemistry on scale adhesion at the leading edge of a flow hole in a heat exchanger  

International Nuclear Information System (INIS)

In the heat exchangers of power plants, scale deposition may occur, especially at the leading edge of contraction. The growth of scale can lead to an increase in pressure and cause oscillation of the water level. In our previous study, the dependence of flow on contraction geometry was analyzed numerically and empirically. It was shown that the contraction ratio of hydraulic diameter of the flow path contributed greatly to the difference in pressure drop and turbulent kinetic energy at the leading edge of the flow path. In this study, the effect of contraction geometry and flow rate on scale adhesion was studied in AVT chemistry at 270degC using a high-velocity scale-adhesion test loop. The differential pressure and the amount of scale deposited due to scale adhesion at the leading edge of the flow path increased more in a quatrefoil-type flow path than in ...

1999-05-01

477

Principles of room air flow; Grundlagen der Raumluftstroemung  

Energy Technology Data Exchange (ETDEWEB)

The following subjects are dealt with: physics of indoor air flow, flow in individual rooms, exchange of air and pollution between individual building zones and with the outside world, thermal coupling with the building shell, thermal comfort and air quality, evaluation of the ventilation. figs., tabs., refs.

1994-12-31

478

N89-20139 - NASA Technical Report Server (NTRS)  

Science.gov (United States)

REAL ENGINE FLOW SIMULATION. 4 C D - 8 5 - 1 6 9 6 4. FIGURE 2. - COMPLEX FLOW PHENOMENA IN A TURBINE PASSAGE,. SEE TABLE I FOR DESCRIPTION OF NUMBERED FLOW ...

479

Multidimensional two-phase flow regime distribution in a PWR downcomer during an LBLOCA refill phase  

Energy Technology Data Exchange (ETDEWEB)

The multidimensional countercurrent two-phase flow regimes that occur in a pressurized-water reactor (PWR) vessel downcomer during the refill phase of a large-break loss-of-coolant accident are studied using a transparent 1/10 scale model of a PWR vessel. The various flow regimes and their distribution in the downcomer have been identified and mapped for a range of air-water flooding experiments. The two-phase flow patterns that are identified in the downcomer included various types of film flows, droplet flows, countercurrent churn flows and cocurrent flows depending on the flooding condition. Through observation of the two-phase flow dynamics it was deduced that the physical mechanisms associated with the flooding processes could be separated into a liquid entrainment process and a film flow ...

1994-09-01

480

Multidimensional two-phase flow regime distribution in a PWR downcomer during an LBLOCA refill phase  

International Nuclear Information System (INIS)

The multidimensional countercurrent two-phase flow regimes that occur in a pressurized-water reactor (PWR) vessel downcomer during the refill phase of a large-break loss-of-coolant accident are studied using a transparent 1/10 scale model of a PWR vessel. The various flow regimes and their distribution in the downcomer have been identified and mapped for a range of air-water flooding experiments. The two-phase flow patterns that are identified in the downcomer included various types of film flows, droplet flows, countercurrent churn flows and cocurrent flows depending on the flooding condition. Through observation of the two-phase flow dynamics it was deduced that the physical mechanisms associated with the flooding processes could be separated into a liquid entrainment process and a film flow ...

1993-10-01

481

Flow regime transition criteria for upward two-phase flow in vertical tubes  

Energy Technology Data Exchange (ETDEWEB)

Traditional two-phase flow-regime criteria based on the gas and liquid superficial velocities may not be suitable to the analyses of rapid transient or entrance flows by the two-fluid model. Under these conditions, it is postulated that direct geometrical parameters such as the void fraction are conceptually simpler and therefore more reliable parameters to be used in flow-regime criteria than the traditional parameters. From this point of view, new flow-regime criteria for upward gas-liquid flow in vertical tubes have been developed considering the mechanisms of flow-regime transitions. These new criteria can be compared to existing criteria and experimental data under steady-state and fully developed flow conditions by using relative velocity correlations. The criteria showed reasonable agreements with the existing data for atmospheric ...

1984-05-01

482

Flow regime transition criteria for upward two-phase flow in vertical tubes  

International Nuclear Information System (INIS)

Traditional two-phase flow-regime criteria based on the gas and liquid superficial velocities may not be suitable to the analyses of rapid transient or entrance flows by the two-fluid model. Under these conditions, it is postulated that direct geometrical parameters such as the void fraction are conceptually simpler and therefore more reliable parameters to be used in flow-regime criteria than the traditional parameters. From this point of view, new flow-regime criteria for upward gas-liquid flow in vertical tubes have been developed considering the mechanisms of flow-regime transitions. These new criteria can be compared to existing criteria and experimental data under steady-state and fully developed flow conditions by using relative velocity correlations. The criteria showed reasonable agreements with the existing data for atmospheric ...

1984-01-01

483

Cross sectional early mitral flow velocity profiles from colour Doppler.  

UK PubMed Central (United Kingdom)

Instantaneous cross sectional flow velocity profiles from early mitral flow in 10 healthy men were constructed by time interpolation of the velocity data from each point in sequentially delayed two...Full Text Available

1989-09-01

484

Chaotic system of two-phase flow in a small, horizontal, rectangular channel.  

Science.gov (United States)

Various measurement tools that are used in chaos theory were applied to analyze two-phase pressure signals with the objective of identifying and interpreting flow pattern transitions for two-phase flows in a small, horizontal rectangular channel. These me...

1995-01-01

485

An investigation into flow regimes for two-phase helium flow  

Energy Technology Data Exchange (ETDEWEB)

The Tevatron accelerator at Fermilab incorporates long two-phase helium passages. During magnet design, the generalized flow map of Baker was used to predict homogeneous flow. Longer than expected magnet time constants led to this investigation. The importance of predicting the flow regime has been amplified with the advent of non-horizontal accelerator designs. A test setup was constructed at Fermilab to investigate two-phase helium flow regimes for conditions practical in accelerator designs. The setup consisted of a standard Tevatron satellite refrigerator, subcooling dewar, heater, 35 m long transfer line, and a specialized end box. A knife blade on the midplane of the transfer line diverted the flow from the upper and lower halves of the pipe to separate vessels in the end box. The amount of liquid above and below the plane was measured at various total mass ...

1987-10-01

486

Airfoil Computation at High Angles of Attack, Inviscid and Viscous ...  

Science.gov (United States)

shown of inviscid shocked flow with and without separation and shock-free flow with separation. An Euler solu- tion with ... THE existence of flow separation and recirculation is ..... Solutions for AGARD Test Cases," NASA TM, to be published. ...

487

Pulsating stochastic flows accompanying microwave filament/supersonic shock layer interaction  

British Library Electronic Table of Contents (United Kingdom)

The details of pulsating stochastic flows accompanying the interaction of a microwave filament (regarded as a heated rarefied channel) and an aerodynamic body in supersonic flow are examined numerically using the Euler equations. Symmetrical and asymmetrical filament locations relative to the aerodynamic body are considered. The flowfields are characterized by large scale pulsations and small scale stochastic fluctuations. The mechanisms of the formation of these flow structures are discussed. Two qualitatively different kinds of flowfields are observed depending on the magnitude of the filament radius, with domination of the pulsations of flow parameters or stochastic phenomena. Flow instabilities inherent to the problems under interest are described. The problems are considered in both p...

2011-01-01

488

Plasma flow measurement using directional Langmuir probe under weakly ion-magnetized conditions  

Energy Technology Data Exchange (ETDEWEB)

It is both experimentally and theoretically demonstrated that ion flow velocity at an arbitrary angle with respect to the magnetic field can be measured with a directional Langmuir probe. Based on the symmetry argument, we show that the effect of magnetic field on directional probe current is exactly canceled in determining the ion flow velocity, and obtain the generalized relation between flow velocity and directional probe currents valid for any flowing direction. The absolute value of the flow velocity is determined by an in situ calibration method of the probe. The applicability limit of the present method to a strongly ion-magnetized plasma is experimentally examined. (author)

2000-07-01

489

Phenomenological modeling of two-phase flow for LWRs. I. Experimental study of hydrodynamics of inverted annular flow. II. Simulation study of hot leg U-bend two-phase flow  

International Nuclear Information System (INIS)

In FY 1984 three specific tasks which are all related to not-well-understood two-phase phenomena of importance to LWR accidents have been identified under the program. These three tasks are: (1) inverted annular flow experiments and modeling; (2) hot leg U-bend two-phase flow simulation study; and (3) development and evaluation of two-phase flow scaling criteria. Some of the important results obtained under Tasks (1) and (2) are reported in this paper.

1984-10-23

490

Mixed convection flow in a horizontal rectangular channel subjected to a horizontal thermal gradient  

British Library Electronic Table of Contents (United Kingdom)

This paper deals with a mixed convection water flow in a horizontal rectangular duct, uniformly heated from one lateral vertical wall and thermally insulated elsewhere. The supplied heat flux induces a secondary flow, which structure is constituted of one longitudinal roll in the considered aspect ratio (??=?1.9), embedded into a return flow of possibly large stream wise extension (up to twenty channel heights). Such situation induces helicoidal trajectories for the fluid flow particles, which contributes to a heat transfer enhancement compared to purely forced convection flow.

2011-01-01

491

Mixed convection flow in a horizontal rectangular channel subjected to a horizontal thermal gradient  

Science.gov (United States)

This paper deals with a mixed convection water flow in a horizontal rectangular duct, uniformly heated from one lateral vertical wall and thermally insulated elsewhere. The supplied heat flux induces a secondary flow, which structure is constituted of one longitudinal roll in the considered aspect ratio (? = 1.9), embedded into a return flow of possibly large stream wise extension (up to twenty channel heights). Such situation induces helicoidal trajectories for the fluid flow particles, which contributes to a heat transfer enhancement compared to purely forced convection flow.

2011-04-01

492

The S407, S409, and S410 Airfoils  

Science.gov (United States)

... 14(a)), a short laminar separation bubble is evident on the ... Natural Laminar Flow and Laminar Flow Control, RW Barnwell and MY ... AGARD CP No. ...

2010-08-01

493

TECHNICAL REPORT - NASA Technical Reports Server  

Science.gov (United States)

VORTEX VALVE FLOW CHARACTERISTICS. 49. VENTED VORTEX VALVE. 50. VORTEX DIVERTER VALVE- ... 46 AND VORTEX MIXING VALVE FLOW CHARACTERISTICS ...

494

Gallbladder function and dynamics of bile flow in asymptomatic gallstone disease  

UK PubMed Central (United Kingdom)

AIM: To investigate the effects of gallbladder stones on motor functions of the gallbladder and the dynamics of bile flow in asymptomatic gallstone disease.METHODS: Quantitative hepatobiliary...Full Text Available

2009-06-14

495

GENERATION OF TURBULENCE IN COUETTE FLOW ...  

Science.gov (United States)

... lated Reynolds number for separation is too small. Now ... lol (1959). 6.) F.Schultz-Grunow On stability of Couette flow, AGARD- ...

1962-03-01

496

Effect of Reynolds Number and Periodic Unsteady Wake Flow ...  

Science.gov (United States)

verse pressure gradient, makes it susceptible to flow separation, ...... AGARD, Lecture Series LS-167. [25] Eifler, J., 1975, Zur Frage der freien ...

497

Demonstration of Separation Delay With Glow ... - GLTRS - NASA  

Science.gov (United States)

flow over the suction surface of a modern low- ..... the flow because of its proximity to the separation point ..... Pressure Turbines, AGARD Lecture Series 167, ...

498

Active Dynamic Flow Control Studies on Rotor Blades  

Science.gov (United States)

... of the cycle shows that the separation area ea. ... with suitable flow solvers based on the Reynolds ... AGARD 75th Fluid Dynamics Panel Meeting and ...

2001-06-01

499

//s /~7 - NASA CR-  

Science.gov (United States)

Valve Flow Characteristics. 3-68. 3-40. Valve Operating Current Vs. Temperature ...... VALVE FLOW CHARACTERISTICS. Acceptance Test 4/29/74. SINs 002 & 004 ...