Lumbricus terrestris (Annelid, Oligocheta) is capable of cellular- and humoral-specific reactions against natural antigens. Is this earthworm able to elaborate a response of antibody type against a...Full Text Available
A complex network approach on a rough fracture is developed. In this manner, some hidden metric spaces (similarity measurements) between apertures profiles are set up and a general evolutionary network in two directions (in parallel and perpendicular to the shear direction) is constructed. Also, an algorithm (COmplex Networks on Apertures: CONA) is proposed in which evolving of a network is accomplished using preferential detachments and attachments of edges (based on a competition and game manner) while the number of nodes is fixed. Also, evolving of clustering coefficients and number of edges display similar patterns as well as are appeared in shear stress, hydraulic conductivity and dilation changes, which can be engaged to estimate shear strength distribution of asperities.
A new /sup 99m/Tc-phosphine-isocyanide complex with the general structure (/sup 99m/Tc (DEPE)/sub 2/(CNR)/sub 2/)/sup +/ has been synthesised and tested in animals and one human. In three animal species (rat, rabbit, dog), the complex is an efficient myocardial imaging agent, while in humans it remains in the blood pool. The complex is 100% protein bound in animals and humans, but whereas in humans it is attached to a 51.5 kdalton protein (probably prealbumin), in rabbits it appears to be bound to a larger macromolecule (M.W.>100 kdalton). The efficiency of the complex for blood pool labelling was tested in a human volunteer and compared with the standard in vivo red cell labelling technique with stannous pyrophosphate. A satisfactory radionuclide angiogram could be performed with less than 370 MBq of the complex. The count rate for the ...
Any molecule which has a hydrogen atom attached directly to oxygen or nitrogen is capable of hydrogen bonding. The molecular complexes formed by hydrogen have particularly attracted considerable attention to understand the nature of the bond. The hydrogen bonded complexes formed by acetonitrile with certain alcohols such as tertiary butyl alcohol, isoamyl alcohol, cyclohexyl alcohol, hexyl alcohol and diethylene glycol in benzene were studied. The dipole moments of 1:1 complexes of the above said systems were determined at 308K. The dipolar increments for these systems were computed from the bond angle data available from molecular orbital studies. All these studied systems show that polarization interaction dominates in all the complexes.
We investigate some aspects of the radiation damage mechanisms in biomolecules, focusing on the modelling of resonant fragmentation caused by the attachment of low-energy electrons (LEEs) initially ejected by biological tissues when exposed to ionizing radiation. Scattering equations are formulated within a symmetry-adapted, single-center expansion of both continuum and bound electrons, and the interaction forces are obtained from a combination of ab initio calculations and a nonempirical model of exchange and correlation effects developed in our group. We present total elastic scattering cross-sections and resonance features obtained for the equilibrium geometries of glycine, alanine, proline and valine. Our results at those geometries of the target molecules are briefly shown to qualitatively explain some of the fragmentation patterns obtained in experiments. We further carry out a one-dimensional (1D) modeling for the dynamics of intramolecular energy transfers ...
BackgroundMeasures of attachment style are often used to appraise social and emotional health. In developmental literature, the concept of attachment is used to explain...Full Text Available
"2"1"1At is one of the most promising radionuclides in #alpha#-radioimmunotherapy (#alpha#-RIT). Unfortunately, biomolecules labeled by direct electrophilic astatination are unstable due to the rapid loss of "2"1"1At under both in vitro and in vivo conditions. The present paper describes the results of our studies on attaching At"- to the rhodium(III) complex with thioether ligand: 1,5,9,13-etrathiacyclohexadecane-3,11-diol (16-S4-diol). Rh"3"+ was chosen as a moderately soft metal cation which should form very strong bonds with soft At"- anions, but first of all because of the kinetic inertness of low spin rhodium(III) d"6 complexes. The 16-S4-diol ligand was selected due to formation of stable complexes with Rh"3"+. The experiments related to optimization of the reaction conditions were performed with the "1"3"1I, basing on a chemical similarity of I"- to At"-. The experiments with "2"1"1At were then ...
Acetohydroxyacid synthase (AHAS; EC 2.2.1.6) is the first enzyme in the biosynthetic pathway of the branched-chain amino acids. It catalyzes the conversion of two molecules of pyruvate into 2-acetolactate or one molecule of pyruvate and one molecule of 2-ketobutyrate into 2-aceto-2-hydroxybutyrate. AHAS requires the cofactors thiamine diphosphate (ThDP), Mg{sup 2+} and FAD for activity. The herbicides that target this enzyme are effective in protecting a broad range of crops from weed species. However, resistance in the field is now a serious problem worldwide. To address this, two new sulfonylureas, monosulfuron and monosulfuron ester, have been developed as commercial herbicides in China. These molecules differ from the traditional sulfonylureas in that the heterocyclic ring attached to the nitrogen atom of the sulfonylurea bridge is monosubstituted rather than disubstituted. The structures of these compounds in complex with the catalytic ...
AbstractBackground: The dinitrofluorobenzene/dinitrosulfonic acid (DNFB/DNS) model was originally described as an experimental model of intestinal inflammation resembling human ulcerative colitis (UC). Due to the absence of acceptable UC experimental models for pharmacological preclinical assays, here we examine the immune response induced in this model. Methods: Balb/c mice were sensitized by skin application of DNFB on day 1, followed by an intrarectal challenge with DNS on day 5. We further expanded this model by administering a second DNS challenge on day 15. The features of colonic inflammation and immune response were evaluated. Results: The changes observed in colonic tissue corresponded, in comparison to the trinitrobenzene sulfonic acid (TNBS) colitis model, to a mild mucosal effe...
This paper describes the design and operating experience with a high performance control system tailored to the requirements of the SuperHILAC accelerator. A large number (20) of the latest 16-bit microcomputer boards are used in a parallel-distributed manner to get a high system bandwidth. Because of the high bandwidth, software costs and complexity are significantly reduced. The system by its very nature and design is easily upgraded and repaired. Dynamically assigned and labeled knobs, together with touch-panels, allow a flexible and efficient operator interface. An X-Y vector graphics system provides for display and labeling of real-time signals as well as general plotting functions. This control system allows attachment of a powerful auxiliary computer for scientific processing with access to accelerator parameters.
Cell surface glycosaminoglycans play important roles in cell adhesion and viral entry. Laboratory strains of two alphaviruses, Sindbis and Semliki Forest virus, have been shown to utilize heparan sulfate as an attachment receptor, whereas Ross River virus (RRV) does not significantly interact with it. However, a single amino acid substitution at residue 218 in the RRV E2 glycoprotein adapts the virus to heparan sulfate binding and expands the host range of the virus into chicken embryo fibroblasts. Structures of the RRV mutant, E2 N218R, and its complex with heparin were determined through the use of electron cryo-microscopy and image reconstruction methods. Heparin was found to bind at the distal end of the RRV spikes, in a region of the E2 glycoprotein that has been previously implicated in cell-receptor recognition and antibody binding.
We wanted to evaluate the usefulness of a new type of a complex expandable nitinol stent that was designed to reduce the stent's propensity to migration during the treatment of malignant gastroduodenal obstructions. Two types of expandable nitinol stent were constructed by weaving a single thread of 0.2mm nitinol wire in a tubular configuration: an uncovered stent 18mm in diameter and a covered stent 16mm in diameter. Both ends of the covered stent were fabricated by coaxially inserting the covered stent into the tubular uncovered stent and then attaching the two stents together with using nylon monofilament. Under fluoroscopic guidance, the stent was placed in 29 consecutive patients (20 men and 9 women, mean age: 65 years) who were suffering with malignant gastric outlet obstruction (n=20), duodenal obstruction (n=6) or combined obstruction (n=3). Clinical improvement was assessed by comparing the food intake capacity before and ...
The guiding mechanism is attached by a hinge (swivel) to the supporting frame, and the frame is equipped by hinges (swivels) with hydraulic or pneumatic cylinders mounted on its ends and is attached by hinges (swivels) to the coke ejector and guide respectively. This increases the productivity and efficiency of operating the system.
Enteric infections with attaching/effacing lesion-inducing bacterial pathogens are a worldwide health problem. A murine infection model with one such pathogen, Citrobacter rodentium,...Full Text Available
Plant surfaces covered with crystalline epicuticular waxes are known to be anti-adhesive, hardly wettable and preventing insect attachment. But there are insects that are capable of gluing their eggs...Full Text Available
We studied the dynamics of microbial communities attached to model aggregates (4-mm-diameter agar spheres) and the component processes of colonization, detachment, growth, and grazing mortality. Agar...Full Text Available
This study examined the hypothesis that solid surfaces may stimulate attached bacteria to produce exopolymers. Addition of sand to shake-flask cultures seemed to induce exopolymer synthesis by a number...Full Text Available
The All Union Scientific Research Institute of Drilling Techniques has developed the SH01-195 spindle deflector designed for use with the 195 millimeter turbodrill sections in place of the standard spindle. This spindle deflector is an axial support for the turbodrill, manufactured as a separate unit that attaches to the turbosections using the standard attachment configuration for series manufactured turbodrills, using the sub for attachment to the frame and a splined half coupling for attachment to the shaft. The spindle deflector itself consists of two parts connected by a curved sub through the frame and by a double hinge to the shaft. The hinge is isolated from axial forces by mounting radial support ball bearings above and below it.
Performance predictions have been made for attached-sunspace types of passively solar heated buildings. The predictions are based on hour-by-hour computer simulations using computer models developed in the framework of PASOLE, the Los Alamos Scientific Laboratory (LASL) passive solar energy simulation program. The models have been validated by detailed comparison with actual hourly temperature measurements taken in attached-sunspace test rooms at LASL.
The purpose of the invention is to improve adaptability of a compression shield to irregularities of a face. This goal is achieved in that a compressible shield is made in the form of a lattice of elastic transverse plates with grooves, elastic vertical elements installed in the grooves, and an elastic plate which is concave toward the face. The plate is located vertically in the middle of the shield. The compressible shield is attached by hinges to a deflector. Telescopic cross pieces are attached by hinges to the covering section of reinforcement, offering the possibility of longitudinal movement at the point of attachment.
Abstract- In our reply to M. H. van IJzendoorn and M. J. Bakermans-Kranenburg (this issue) and R. A. Thompson (this issue), we highlight 2 challenges that attachment researchers face today: (a) closing the gap between the developmental and social psychological traditions and (b) connecting attachment theory to the broader field of evolutionary psychology. We contend that an evolutionary life history approach can contribute to both goals and argue that attachment researchers should consider moving beyond some of Bowlby's original formulations in order to permit further advancement of the field. Finally, we review van IJzendoorn and Bakermans-Kranenburg's criticism of the hypothesis that sex differences in attachment arise in middle childhood; we conclude that the claim that the hypothesis h...
The synthesis, characterization of M"vO([CH_3CH_2N(CH_2CH_2S)_2](p-S-Ph-COOCH_2-CH_3)) (M:"9"9"mTc: I, Re: II) is presented in this work, where a pendant ester function is attached to the monothiolate ligand. Chemical structure of I is established after chromatographic comparison with II, synthesized in macroscopic amounts. Complex II is fully characterized by classical methods of analysis showing that the compound adopts a distorted trigonal bipyramidal configuration around the metal. The two sulfur atoms of the tridentate ligand and the oxo group form the basal plane, while the remaining nitrogen atom of the tridentate ligand and the sulfur atom of the monothiolate ligand occupy the apices of the bipyramid. In vitro challenge experiments with glutathione (GSH) in neutral aqueous medium demonstrate, that I suffers nucleophilic attack by GSH and thereby transformation to a more hydrophilic daughter metal compound. Formation of the latter ...
An improved labeling procedure for peptides attached to organometallic 99mTc(III) '4+1' mixed-ligand complexes in which the radiometal is coordinated by a tripodal tetradentate chelator 2,2',2''-nitrilotriethanethiol (NS3) and a monodentate isocyanide ligand is presented. The labeling procedure was evaluated by the synthesis of [99mTc(NS3)(L2-RGD)]. The containing radiopharmaceutically interesting RGD-peptide cyclo[Arg-Gly-Asp-D-Tyr-Lys] was modified with 4-isocyanobutanoic acid (L2) as linker conjugated to N6-Lys to get the monodentate ligand L2-RGD. The structural identity of the 99mTc-conjugate was confirmed by comparison to a Re reference compound. The Tc- and Re-conjugates had matching retention times under identical HPLC conditions. The 99mTc-labeling was performed in a novel one-step procedure using the eluate of a 99Mo/99mTc generator, NS3, the isocyanide modified peptide, SnCl2, Na2EDTA, mannitol and ascorbic acid in the reaction ...
Purpose: Antitumor activity of the dichloroplatinum(II)-histamine complexes labeled with I-125 or I-131 was investigated in a transplantable murine adenocarcinoma (MA) model. Methods: The tumor model was obtained in C3H/W female mice after subcutaneous inoculation of the tumor cells derived from the mice bearing a mammary tumor of spontaneous origin. Antitumor activities of the platinum-histamine complexes were investigated in three independent experiments, which differed in applied doses of preparations (PtCl{sub 2}Hist, PtCl{sub 2}[{sup 125}I]Hist, PtCl{sub 2}[{sup 131}I]Hist, PtCl{sub 2}Hist/PtCl{sub 2}[{sup 125}I]Hist and PtCl{sub 2}Hist/PtCl{sub 2}[{sup 131}I]Hist), treatment schedules as well as stages of the disease progress in the animals used. Experiment 1 included long-term, multidose treatment with low single doses (treatment duration 31-32 days; 8-10 doses of ca. 0.25{center_dot}MTD{sub Pt} each). Experiment 2 included short-term, ...
Ever-present water vapor and dust distort or block incoming radiations. ... were among the first scientific sensors to be attached to the earliest space rockets. ...
The central features of the mechanical cycle that drives the contraction of muscle are two translational steps: the working stroke, whereby an attached myosin crossbridge moves relative to the actin...Full Text Available
... one for each node, and an i/o queue to manage ... ecuted as if it came from a terminal attached to a ... In its default mode PC-NETSIM is stochastic, that is ...
Tobacco use has been recognized to be a significant risk factor for the development and progression of periodontal disease. Its use is associated with increased pocket depths, loss of periodontal attachment,...Full Text Available
The effects of low concentrations (10 nm or less) of indoleacetic acid and abscisic acid on the phytochrome-mediated attachment of barley root (Hordeum vulgare L., var. Compana)...Full Text Available
The force required to break the conidium-conidiophore attachment in Helminthosporium maydis was measured by centrifugation and by a small jet of air. The force which removed half the...Full Text Available
The aim of this project is to investigate the dependence of the cross sections for dissociative electron attachment to a molecule on the initial rovibrational state of the molecule. An enhancement of the cross section results in the enhancement of the rate of production of negative ion beams. Preliminary investigations reveal that for lithium dimers, Li/sub 2/, the peak attachment cross sections can increase by almost an order of magnitude if the molecule is initially vibrationally excited to the v = 1 level. Excitation to higher vibrational levels would result in further enhancement of the attachment rates. As part of present investigations, the cross sections for vibrational excitation of various molecules, using both resonant and nonresonant mechanisms is calculated.
Data were collected on 154 adoptive families with gay/lesbian and straight adoptive parents (154 parent respondents and 210 adolescent respondents). This study was principally interested in factors affecting adolescent attachment including parent sexual orientation, adolescent and parent life satisfaction, and parent level of relationship satisfaction with their adopted child as well as other key parent, child and adoption characteristics. The results suggest that higher level of adopted adolescent attachment to parents is not related to adoptive parent sexual orientation. Adolescent attachment to parents is related to adolescent life satisfaction; parent level of relationship satisfaction with their adopted child, number of placements prior to adoption, and adolescent's current age. Adole...
A design is proposed for forming the rear screen of a chamber firebox at the point of aerodynamic projection and a design for attaching the pipes of the aerodynamic projection using girders linked with the screen by hinges and movable connections.
The modification of polymers by radiation grafting has been utilized for several decades. The penetrability of gamma rays allows to modify the internal surfaces of porous materials retaining its mechanical properties. In recent years applications of these materials to obtain chromatographic supports and biocatalysts have been reported. In this work, we described the grafting of glycidyl methacrylate (GMA) onto a macroporous polysulfone polymer. Reproducible amount of grafting, from 10% to 60% was obtained by choosing favourable monomer concentration and gamma radiation doses from 6 kGy up. Afterwards, iminodiacetic acid (IDA) and amino phenyl arsine oxide (PAO) were covalently attached to the grafted polyGMA, in correspondence with the grafting degree. Later on, a recombinant histidin-patch thioredoxin protein (HP-rTrx) was immobilized onto this surface by two different ways, involving specific protein orientations. The first one involves an IDA-Ni{sup 2+} ...
Research at the interface between biomolecules and inorganic nanocrystals has resulted in a great number of new discoveries. In part this arises from the synergistic duality of the system: biomolecules may act as self-assembly agents for organizing inorganic nanocrystals into functional materials; alternatively, nanocrystals may act as microscopic or spectroscopic labels for elucidating the behavior of complex biomolecular systems. However, success in either of these functions relies heavily uponthe ability to control the conjugation and assembly processes.In the work presented here, we first design a branched DNA scaffold which allows hybridization of DNA-nanocrystal monoconjugates to form discrete assemblies. Importantly, the asymmetry of the branched scaffold allows the formation of asymmetric2assemblies of nanocrystals. In the context of a self-assembled device, this can be considered a step toward the ability to engineer functionally distinct inputs and ...
We describe the synthesis of metal-chelating polymers (MCPs) with four different pendant polyaminocarboxylate ligands (EDTA, DTPA, TTHA, DOTA) and an orthogonal end-group, either a fluorescein molecule or a bismaleimide linker for antibody attachment. Polymer characterization by a combination of (1)H NMR, UV/vis absorption measurements, and thermal gravimetric analysis (TGA) indicated that each chain of the fluorescein-terminated polymers contained one dye molecule. These polymer samples were loaded with three different types of lanthanide ions as well as palladium and platinum ions. The numbers of metal atoms per chain were determined by a combination of UV/vis and conventional ICP-MS measurements. The experiments with lanthanide ions demonstrated that a net anionic charge on the polymer is important for water solubility. These experiments also showed that at least one type of lanthanide ion (La(3+)) is capable of forming a bimetallic complex ...
A slurry intake device is proposed which contains an inlet sleeve, housing with grating installed with the discharge end in the zone of the slurry outlet, and hinged deflector. In order to conserve the clay mud, it is equipped with a tie rod and two-arm lever which is kinematically linked to the deflector and the grating. It is installed by hinges in relation to the housing and the latter is attached by hinges to the inlet sleeve. The deflector is arranged in the zone of slurry outlet. The device is distinguished by the fact that the deflector is equipped with a cantilever on which a fixable weight is attached.
A string sieve is proposed which includes a frame, a sifting surface made of string, a device for attaching the strings made in the form of rollers installed in staggered order and a tensing device attached to traverses. To improve the effectiveness of sifting by self cleaning of the sifting surface during operation, the rollers are installed on the traverses by means of a unit of hinges, whose elastic elements are made with varying rigidity.
There is a renewed interest in straight wing vertical axis wind turbines (SW-VAWT) which are usually installed on the roofs of high buildings in cities, urban areas and high mountain areas for independent electric power supply. SW-VAWTs have the advantages of simple design and low cost, as well as wind direction independence compared to the horizontal system. However, when SW-VAWTs are installed in cold regions, ice, snow and other attachments can affect its performance. In this study, clay was attached to the leading edge of the blade surface to determine how the performance of SW-VAWTs are affected by the mechanism of icing. Wind tunnel tests were used to study the rotational performance and power performance of the turbine blades. Icing prevention was also investigated. The attachment of clay on the leading edge of blade surface made the rotational performance of the SW-VAWT worse. The attachment of ...
This research proposes that the concept of emotional attachment, and specifically the independent constructs of psychological ownership and affective reaction, can help explain many of the endowment effect findings documented in the literature. We define these constructs and then test them across a set of nine studies in which we both replicate previous and generate new endowment effect findings, and then show that psychological ownership and affective reaction can mediate the effects. In doing so, we offer direct empirical support for the idea of emotional attachment as a driver of loss aversion while also providing practitioners and future endowment effect researchers with new insights about the psychological processes that underlie the endowment effect.
We investigate the limiting behavior of random tree growth in preferential attachment models. The tree stems from a root, and we add vertices to the system one-by-one at random, according to a rule which depends on the degree distribution of the already existing tree. The so-called weight function, in terms of which the rule of attachment is formulated, is such that each vertex in the tree can have at most K children. We define the concept of a certain random measure mu on the leaves of the limiting tree, which captures a global property of the tree growth in a natural way. We prove that the Hausdorff and the packing dimension of this limiting measure is equal and constant with probability one. Moreover, the local dimension of mu equals the Hausdorff dimension at mu-almost every point. We give an explicit formula for the dimension, given the rule of attachment.
OmpU porins are increasingly recognized as key determinants of pathogenic host Vibrio interactions. Although mechanisms remain incompletely understood, various species, including the...Full Text Available
The formation and maintenance of social bonds in adulthood is an essential component of human health. However studies investigating the underlying neurobiology of such behaviors have been scarce....Full Text Available
Most insects are thought to fly by creating a leading-edge vortex that remains attached to the wing as it translates through a stroke. In the species examined so far, stroke amplitude is large, and...Full Text Available
Adult meadow voles (Microtus pennsylvanicus) are solitary in the spring–summer reproductive season, but during winter months, females and males are socially tolerant...Full Text Available
A roller bearing hot box sensor utilizing a metallic temperature sensitive elongated wire element. The wire element contacts at temperatures in the range of about 125 F to about 225 F so that when the contraction movement of the wire is attached to a conn...
This report presents geologic considerations that are pertinent to the Remedial Action Plan for Slick Rock mill tailings. Topics covered include regional geology, site geology, geologic stability, and geologic suitability.
The phytochrome-mediated attachment of root tips of mung bean (Phaseolus aureus) and barley (Hordeum vulgare) to glass is affected by the prior exposure of hydrated...Full Text Available
Up-flow anaerobic attached-growth bioreactors filled with pre-treated coir fibres ...coir-fibre arranged in bottle-brush configuration bounded by a novel plastic binding technique ...-three anaerobic filter reactors in series -coir fibre as the bacteria growth media a sedimentation
The phytochrome-mediated attachment of mung bean (Phaseolus vulgaris L., var. Oklahoma 612) root tips on glass is quickly affected by indoleactic acid and abscisic acid at concentrations...Full Text Available
Candida albicans frequently causes superficial infections by invading and damaging epithelial cells, but may also cause systemic infections by...Full Text Available
The article describes the caregiving responsibility to provide food for chronically ill family members and the meanings attached to food and eating when ill created stress for family caregivers. The...Full Text Available
Merozoite surface proteins have been implicated in the initial attachment to the host red blood cell membrane that begins the process of invasion, an important step in the life cycle of the malaria...Full Text Available
A pneumatic device is in the form of a U-shaped frame, on which a prong is attached by using two pairs of levers. It also has a hydraulic or pneumatic cyclinder, whose rod is connected to one of the pairs of levers. All connections are hinges.
Hollow needles made of an electrically conducting material are attached by hinges in the openings of the perforated end of an insert in order to intensify heat and mass transfer. The free sections of the needles are placed outside the insert, and a wick is placed on the wall of the frame in the condensation area. The wick overlaps the inlet openings of the insert.
A preliminary chemical characterization is presented of phosphate-free aminolipids isolation from Chlorobium limicola f. thiosulfatophilum. The lipid contains no phosphorus, glycerol, sugar, ornithine, or lysine. Ultraviolet absorption and fluorescence spectra indicate that the amino moiety of the lipid is an aromatic heterocyclic compound. Infrared spectra indicate that the lipid is a secondary or tertiary amide, and gas chromatograhic analysis of the hydrolyzed lipid shows that for each 1100 g of lipid, 1 mol of myristic acid (C/sub 14:0/) is linked in an amide bond. Acid hydrolysis of the lipid yields two fluorescent substances, A (ninhydrine positive) and B (negative), in addition to myristic acid. Proton nuclear magnetic resonance (NMR) studies indicate that substance A contains a butyl groups attached to a conjugated ring carbon, two equivalent ethyl groups attached to one or two nitrogen atoms, and two downfield protons (8.4 ppm), ...
The formation of astatide-mercury complexes was investigated in aqueous solutions.The obtained complexes were examined by paper electrophoresis. It was found that Hg(OH)At and Hg(OH)I complexes were formed in neutral solution. The stability constants of the obtained complexes were determined by ion-exchange. The preliminary results indicate that the complex of mercury with astatide is much more stable than similar complexes with iodide. (author)
In October 1992, the US Department of Energy, Richland Field Office (RL) requested that Westinghouse Hanford Company (WHC) respond to a letter from EM-331 asking for completion of a survey of items in storage but not categorized as waste (Roberts 1992). The letter contained an attachment with instructions on how to fill out the attached form and what to exclude from the survey (Appendix A). This report is a summary of the information from the response issued to RL. This report primarily is for use in estimating future waste volumes that may have been overlooked because of the nature of their classification as material not categorized as waste (MNCAW) (i.e., not yet declared Waste).
Hitherto in this laboratory, ionization coefficients alpha and attachment coefficients #eta# have been determined from Townsend's discharge experiments by a curve-fitting method. However, the method proved to be laborious, Formulae have been derived in this paper to give value of alpha and #eta# as a function of Isubo, Isub1 and Isub2 where Isubo is the photoelectric current at a gap setting d and Isub2 the current at another gap setting 2 d. The values of alpha and #eta# obtained give currents in agreement to within 3% in the best cases with the observed currents.
We consider the problem of minimal (multiplicative) complexity of polynomial multiplication and multiplication in finite extensions of fields. For infinite fields minimal complexities are known [Winograd,...Full Text Available
The complex formation of zirconium with biphenyl mono- and biscatecholyazo derivatives has been studied spectrophotometrically. The composition of the complexes, form and charge of complex-forming zirconium ions have been established. A procedure is suggested for calculation of molar absorptivities and stability constants for each of the complexes formed simultaneously in the system. Possible complex formation schemes have been studied. The data obtained were used to develop a spectrophotometric method of determining zirconium in the presence of large amounts of copper.
Cyclotomic fast Fourier transforms (CFFTs) are efficient implementations of discrete Fourier transforms over finite fields, which have widespread applications in cryptography and error control codes. They are of great interest because of their low multiplicative and overall complexities. However, their advantages are shown by inspection in the literature, and there is no asymptotic computational complexity analysis for CFFTs. Their high additive complexity also incurs difficulties in hardware implementations. In this paper, we derive the bounds for the multiplicative and additive complexities of CFFTs, respectively. Our results confirm that CFFTs have the smallest multiplicative complexities among all known algorithms while their additive complexities render them asymptotically suboptimal. However, CFFTs remain valuable as they have the smallest overall ...
A spectrophotometric study has been made of the complex formation of vanadium (3) with arsenazo(1), arsenazo(3) and some monosubstituted derivatives of chromotropic acid and sulphanylamides. In acid medium vanadium (3) reacts with each of these reagents to produce a 1:1 complex. Optimum conditions of the complex formation was found. The effect of H"+ on the complex formation of vanadium (3) with chromotropic acid derivatives was established. It was found by the graphical method that the formation of the complex is accompanied by the elimination of one proton. Patterns were found of the influence of the nature of substituents in the organic compound on the ionization constants of acid groups and stability of complexes. Molar extinction coefficients, equilibrium constants of the formation reactions and instability constants for the complexes ...
Proposed future space-based beam weapons systems will most probably require an intense neutral particle beam for effective operation across geomagnetic field lines. Such neutral beams can most efficiently be obtained by stripping excess electrons from negative ion beams. The objective of this work is to study the process of dissociative attachment of electrons. Specifically, to measure the cross sections for polar dissociation and dissociative attachment for production of H(-). It is suspected that these dissociative attachment cross sections for the production of H(-) from alkali hydrides are large. The insight gained from this study will be extremely helpful in the fabrication of high current density H(-) beam sources for use in the production of intense neutral hydrogen beams. A selection of alkali hydride molecules will be investigated in order to determine the largest cross sections for the production of H(-) by ...
In this article, we present our consistent efforts to explore the dynamical pathways of the migration of electronic radiation by using ultrafast (picosecond/femtosecond time scales) F?rster resonance energy transfer (FRET) technique. The ultrafast non-radiative energy migration from an intrinsic donor fluorophore (Tryptophan, Trp214) present in domain IIA of a transporter protein human serum albumin (HSA) to various non-covalently/covalently attached organic/inorganic chromophores including photoporphyrin IX (PPIX), polyoxovanadate [V15As6O42(H2O)]-6 clusters (denoted as V15) and CdS quantum dots (QDs) has been explored. We have also used other covalently/non-covalently attached extrinsic fluorogenic donors (NPA, ANS) in order to exploit the dynamics of resonance energy migration of an enz...
Knighton et al. used a pulsed high pressure mass spectrometer to examine thermal electron detachment from C_6F_6"-. This technique had been used earlier for the measurement or detachment rate coefficients for azulene anions as a function of temperature. C_6F_6"- and c-C_4F_6"- have been studied by Datskos et al. using a pulsed drift tube. In our laboratory, we have used a flowing afterglow Langmuir probe (FALP) apparatus to measure the thermal electron detachment rate coefficient for c-C_4F_8"- ions at 375 K. We have also measured the electron attachment rate coefficient for c-C_4F_8 at 303 K and 375 K. (author).
In this paper the availability and properties of radioisotopes for both radioimmunodiagnosis (RAID) and radioimmunotherapy (RAIT) are discussed. Examples are provided for radioisotopes available via direct production in nuclear reactors and accelerators or as daughters obtained from radionuclide generator systems whose parents are either reactor or accelerator produced. Important factors which must be considered for the use of a particular radioisotope include availability, the physical half-life and decay properties, and chemical versatility for protein attachment. Although both direct'' and indirect'' methods are available for attachment of radioisotopes to antibodies, this broad field of research is not reviewed in detail. Practical issues related to the availability and use of a variety of radionuclides are described. 47 refs., 5 tabs.
We report synthesis, characterization and ion transport in polyether-based ionic melt electrolytes consisting of Li salts of low-basicity anions covalently attached to polyether oligomers. Purity of the materials was investigated by HPLC analysis and electrospray ionization mass spectrometry. The highest ionic conductivity of 7.1 x 10{sup -6} S/cm at 30 deg. C was obtained for the sample consisting of a lithium salt of an arylfluorosulfonimide anion attached to a polyether oligomer with an ethyleneoxide (EO) to lithium ratio of 12. The conductivity order of various ionic melts having different polyether chain lengths suggests that at higher EO:Li ratios the conductivity of the electrolytes at room temperature is determined in part by the amount of crystallization of the polyether portion of the ionic melt.
We report synthesis, characterization and ion transport in polyether-based ionic melt electrolytes consisting of Li salts of low-basicity anions covalently attached to polyether oligomers. Purity of the materials was investigated by HPLC analysis and electrospray ionization mass spectrometry. The highest ionic conductivity of 7.1 x 10-6 S/cm at 30 deg. C was obtained for the sample consisting of a lithium salt of an arylfluorosulfonimide anion attached to a polyether oligomer with an ethyleneoxide (EO) to lithium ratio of 12. The conductivity order of various ionic melts having different polyether chain lengths suggests that at higher EO:Li ratios the conductivity of the electrolytes at room temperature is determined in part by the amount of crystallization of the polyether portion of the ionic melt.
The foundation of a drill unit for cluster drilling of wells is proposed, which includes support, intermediate, and primary girders, forward and rear carts attached to them, railways and traction units. In order to improve operating reliability of the device during unloading on the cart during drilling and placement of the elevator and movement of the foundation within the area of the cluster of boreholes, it is equipped with controllable rods for connecting the carts to one another with the power component. Each of the power components is attached by hinges to a cart and intermediate girder, while the railways with parts are located on supporting girders. The forward carts are connected to the traction units. In order to reduce labor in moving the foundation to a new borehole of the cluster the foundation has brackets and temporary support. The power components have braces which are connected by hinges to them in the intermediate girders.
Dissociative electron capture to CCl_4 is studied by measuring the angular and velocity distribution of Cl"- ions produced in collisions with velocity selected K(np) Rydberg atoms. Analysis of the data using a Monte Carlo collision code that models the detailed kinematics of the reaction indicates that the lifetime of the CCl_4"- intermediate formed by Rydberg electron capture is 7.5 #+-# 2.5 ps and that, upon dissociation, only a small fraction of the excess energy of reaction appears as translational energy of the Cl"- and CCl_3 fragments. The present approach is one of the few experimental techniques yet devised that can probe the lifetimes of collisionally-produced excited states on a picosecond timescale, and demonstrates that Rydberg atoms provide a unique tool with which to investigate the dynamics of dissociative electron attachment. Measurements are being extended to additional species, including CFCl_3.
Forced harmonic vibration of a non-uniform elastic beam with attached dynamic vibration absorbers (DVA) is studied. Analytical approximation of the solution is obtained by the functional perturbation method (FPM). The problem has application to cutting tools operations where the resistance of the tool holder against regenerative chatter can be enhanced by optimizing the real part of the frequency response function (FRF). A test case of a beam with step-like heterogeneity and single DVA at the tip shows that the FPM solution is very accurate for up to ?40 percent deviation in both stiffness and mass density. Using the analytical results and Sims approach, optimal DVA tuning is found for each set of beam heterogeneity parameters by solving a set of nonlinear algebraic equations numer...
Halide complexes of astatine cations At"+ and AtO"+ were prepared and their rate of migration was measured. The complexes are of the type AtX_2"- and AtOX_2"- (X = Cl"-, Br"-, I"-). The bromo complexes, AtBr_2"- and AtOBr_2"-, have a higher stability than the chloro complexes. The hydrolysis in weakly alkaline solution of AtX_2"- resulted At"-, and that of AtOX_2"- AtO_2"-. (author).
BackgroundHigh complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation Entropy...Full Text Available
The CCR4-NOT complex is the main enzyme catalyzing the deadenylation of mRNA. We have investigated the composition of this complex in Drosophila melanogaster by immunoprecipitation...Full Text Available
Target of rapamycin (TOR) kinases control cell growth through two functionally distinct multiprotein complexes. TOR complex 1 (TORC1) controls temporal cell growth and is sensitive to rapamycin, whereas...Full Text Available
During the past 3 years, progress was made in elucidating the excited state structures of Pt(diimine)(dithiolate) complexes, while more recent efforts focused on the photochemistry of these complexes and electronic structure of other dithiolate systems. A carbonyl-Ir-maleonitrile dithiolate complex is also studied.
BackgroundIn this study we investigated the predictability of three thermodynamic quantities related to complex formation. As a model system we chose the host-guest complexes of...Full Text Available
Ligand exchange of hydrated metal complexes is common in chemical and biological systems. Using the ultrafast T-jump, we examined this process, specifically the transformation of aqua cobalt (II) complexes...Full Text Available
The Δ- and Λ-isomerism of octahedral metal complexes is employed as a source of chirality for inducing chiral nematic phases. By applying a wide range of chiral metal complexes as a...Full Text Available
Werner syndrome (WS) is a rare disorder characterized by the premature onset of several pathologies associated with aging. The gene responsible for WS codes for a RecQ-type DNA helicase and is believed...Full Text Available
This patent describes a system for controlling erosion of the slope between the waterline of a shoreline. The system comprises an elongated conduit; means to pivotably secure the conduit to the shoreline approximately at the waterline; a plurality of individual armor bags attached to the conduit; and means for filling all of the individual armor bags with a grout material whereby the armor bags when filled with the grout material will be positioned as a unit onto the slope below the waterline.
Monochromator stabilization (MOSTAB) is a feedback control system to stabilize an x-ray beam of synchrotron radiation. It applies a feedback voltage to a piezo electric transducer attached to a double-crystal monochromator. We developed MOSTAB modules and examined their performances using SPring-8 beamlines. The x-ray beam position stabilization using MOSTAB was realized simultaneously with the x-ray beam intensity stabilization. As an example of its application, we performed EXAFS measurement with MOSTAB. (author)
The nuclear power plants with WWER type reactors are characterized by horizontally situated steam generators (SG). During seismic event the horizontal and vertical ground accelerations induce fluid motion in directions of longitudinal and transversal axis. Resulting dynamic forces act on the SG attachment and could cause the failure of screws. In obvious PSA scenarios, these phenomena are classified as a indirect induced LOCA. In this paper the effects of transversal sloshing of fluid are analyzed.
A detailed definitive cost estimate is given for an ethanol/gasohol storage and blending terminal serving a planned distillery at a Louisiana sugar factory. Included are an analysis of the accuracy of the estimate, labor rates efficiency, materials and labor escalation, as well as detailed calculations for each account of the project. (LEW)
A piezoelectric biosensor substrate useful for immobilizing biomolecules in an oriented manner on the surface of a piezoelectric sensor has a ladder polymer of polyacrylonitrile. To make the substrate, a solution of an organic polymer, preferably polyacrylonitrile, is applied to the surface of a piezoelectric sensor. The organic polymer is modifying by heating the polymer in a controlled fashion in air such that a ladder polymer is produced which, in turn, forms the attachment point for the biomolecules comprising the piezoelectric biosensor. 3 figs.
The IAEA Department of Safeguards established a project in 1996 for the year 2000 (Y2K) conversion activities. This project covered assessment, conversion and testing of the software applications, instrument evaluation software, embedded systems and Personal Computer (PC) hardware attached to various equipment. Significant progress has been made in converting the applications and instruments to be year 2000 compliant. At the same time Member states have made an effort as well in converting the systems used jointly at the facilities
The effects of neuroactive steroids on the function of GABAA receptors were studied using cell-attached records of single channel activity recorded from HEK293 cells transfected with α1...Full Text Available
The objective of this project is the development of a new class of metalloporphyrin materials used as catalsyts for use in fuel cell applications. The metalloporphyrins are excellent candidates for use as catalysts at both the anode and cathode. The catalysts reduce oxygen in 1 M potassium hydroxide, as well as in 2 M sulfuric acid. Covalent attachment to carbon supports is being investigated. The computer-aided molecular design is an iterative process, in which experimental results feed back into the design of future catalysts.
The purpose of this invention is to assure operating reliability of a Mandrel head in tubes of various diameters. This goal is achieved in that it is equipped with movable expanding sectors, which are installed on a rigid conical plunger dye. It is also equipped with spring-loaded conical slides blocks which are installed on a shaft. The upper ends of the sectors of the sectorial head are attached by hinges to a rigid cone shaped plunger dye. The lower ends are installed with the possibility of interacting with the slide blocks.
This document, the Standards/Requirements Identification Document (S/RID) Phase 2 Assessment Report for the subject facility, represents the results of a Performance Assessment to determine whether procedures containing S/RID requirements are fully implemented by field personnel in the field. It contains a summary report and three attachments; an assessment schedule, performance objectives, and assessments for selected functional areas.
In this contribution we compare the electron scattering processes observed in pure O_2 clusters and mixed clusters like O_2/Ne, O_2/Ar and O_2/N_2. The overlap and positions of the potential curves of O_2 states show the different possible electron attachment processes and also explain the formation of O_2 in clusters. (author).
This is a patent for a device to increase compaction of the loaded batch in a coking chamber that assures a balanced compaction of the batch from the upper to the bottom layer. The leveling rod has a device on the external end that causes the rod to shift vertically and bring pressure on the material and the pressing attachment. Opposite the loading hoppers of the coking chambers there are guides that ensure the rod will be sunk perpendicularly into the loaded material.
A portable fiber optic detector that senses the presence of specific target chemicals by electrostatically attracting the target chemical to an aromatic compound coating on an optical fiber. Attaching the target chemical to the coated fiber reduces the fluorescence so that a photon sensing detector records the reduced light level and activates an appropriate alarm or indicator.
This report measured the rate of isothermal deposition of sub-micron particles of magnetite onto the surface of Alloy 800 at pH of 4.2-9.3 at Re=10,000 and a fluid temperature of 25C. Deposition is modelled as a two-step process, the transport of particles to the surface region followed by attachment to the surface.
Using an anti-receptor mAb that blocks the attachment of echovirus 7 and related viruses (echoviruses 13, 21, 29 and 33), we have isolated a complementary DNA clone that encodes the human decay-accelerating...Full Text Available
The paper contains a numerical evaluation of the expressions for the absorptive potential in heavy ion reactions given earlier. With a standard folding expression for the real part of the ion-ion potential general good agreement is found with experimental data for the angular distributions of elastic and inelastic scattering. Special interest is attached to the case of /sup 16/O + /sup 28/Si where the calculated imaginary potential is very small at low bombarding energies.
The paper contains a numerical evaluation of the expressions for the absorptive potential in heavy ion reactions given earlier. With a standard folding expression for the real part of the ion-ion potential general good agreement is found with experimental data for the angular distributions of elastic and inelastic scattering. Special interest is attached to the case of "1"6O + "2"8Si where the calculated imaginary potential is very small at low bombarding energies. (orig.).
Research is described in the development of organometallic reagents in which the boron was attached to a nonreactive organic or inorganic matrix such as polystyrene, silica, or alumina. We developed the synthesis of oxygen-15 labelled butanol, which has been found to be a valuable blood flow agent in humans. We have also developed a series of polymeric borane derivatives which were used to prepare nitrogen-13 labelled amines.
We used bovine intestinal organ culture to study infection by enterohemorrhagic Escherichia coli serogroups O157, O26, and O111. We show colonization and attaching and effacing lesion...Full Text Available
A concentrator which contains mirrors installed on a carrier frame by means of hinges is described. In order to improve the performance of a concentrator it contains a mechanism for controlling radiation density in a form of a screw attached to the carrier frame. It also contains a circular sliding coupling on the frame which has an annular groove with levers placed in it. The mirrors are connected to the sleeve by means of the levers, and the hinges are made cylindrical and have axes that are perpendicular to the axes of the screw.
The purpose of the invention is to simplify assembly and to reduce labor intensity. This is achieved by the fact that the assembly shaft is positioned in a hawser, while its wall which is turned towards the body of the installation is combined with the hawser wall, where a U shaped opening is made in the wall of the assembly shaft, along the edges of which there is a hermetically sealing device, while the bottom of the body of the offshore drilling rig is equipped with a rigid insert attached with the capability of adjoining it with the hermetically sealing device.
The Gordon Research Conference (GRC) on 2004 Gordon Research Conference on Reversible Associations in Structure & Molecular Biology was held at Four Points Sheraton, CA, 1/25-30/2004. The Conference was well attended with 82 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students.
In an effort to develop octahedral metal complexes as chemotherapeutic and diagnostic agents targeted to DNA, it is critical to optimize the properties of their cellular uptake. Appending d-octaarginine...Full Text Available
Platinum(II) complexes have been investigated in the hydration of alkynes. These catalysts offer improved regioselectivity over Hg(II) counterparts. 1 fig., 2 tabs.
The use of Chelex resin for the synthesis of radioactive lead complexes has been explored. The process involved immobilization of {sup 203}Pb on the resin and subsequent elution of complexed lead by chelating agents. {sup 203}Pb complexes derived from meso- and racemic dimercaptosuccinic acid (meso-DMSA, rac-DMSA) were prepared and assessed for stability in vitro.
The use of Chelex resin for the synthesis of radioactive lead complexes has been explored. The process involved immobilization of "2"0"3Pb on the resin and subsequent elution of complexed lead by chelating agents. "2"0"3Pb complexes derived from meso- and racemic dimercaptosuccinic acid (meso-DMSA, rac-DMSA) were prepared and assessed for stability in vitro.
Given a countable set X (usually taken to be the natural numbers or integers), an infinite permutation, \\pi, of X is a linear ordering of X. This paper investigates the combinatorial complexity of infinite permutations on the natural numbers associated with the image of uniformly recurrent aperiodic binary words under the letter doubling map. An upper bound for the complexity is found for general words, and a formula for the complexity is established for the Sturmian words and the Thue-Morse word.
Dithiolato-nickel complexes with multisulfur ligands derived from benzenehexathiolate have been synthesized. The properties of the monomeric and polymeric complexes have been characterized by ESR spectroscopic and magnetochemical data and by electrical conductivity measurements. The prepared complexes are paramagnetic and have characteristic absorptions between 800 and 1000 nm. (orig.).
The complexing of paramagnetic salts of molybdenum and tungsten with tri-tert-butylphenyl ester of 1,2-naphthoquinone-diazide-(2)-5-sulfochloride is studied by PMR and EPR methods. From the changes of half-widths of lines in PMR spectra and analysis of g-factor in EPR spectra, the kinetic and thermodynamic parameters of the complexing are determined, and the composition of the complexes formed is established, and the schemes of their formation are suggested.
This paper describes the search for new potential chemotherapeutic agents based on transition metal complexes with planar ligands. In this study, palladium polypyridyl complexes were synthesized and characterized by elemental analysis, NMR, UV-VIS and IR spectroscopies. The interaction of the complexes with DNA was also investigated by spectroscopic methods. All metal-to-ligand charge transfer (MLCT) bands of the palladium polypyridyl complexes exhibited hypochromism and red shift in the presence of DNA. The binding constant and viscosity data suggested that the complexes [PdCl{sub 2}(phen)] and [PdCl{sub 2}(phendiamine)] interact with DNA by electrostatic forces. Additionally, these complexes induced an important leishmanistatic effect on L. (L.) mexicana promastigotes at the final concentration of 10 {mu}mol L{sup -1} in 48 h. (author)
Spectrophotometric methods were used to investigate the properties of neptunium(VII), (VI), and (V) in silicate solution. The transition of cationic neptunium(VII) to anionic species in non-complexing environments proceeds in the range of ?? 5.5 to 7.5. In the presence of carbonate, this transition occurs at ?? 10.0 to 11.5 and in silicate solutions at ?? 10.5-12.0. These findings show that cationic neptunium(VII) forms complexes with both carbonate and silicate and that the silicate complex is stronger than that of the carbonate. The competition of complex formation reactions for neptunium(VI) with carbonate and silicate and on the known complex stability constant of NpO2(CO3)34- allowed the NpO2SiO3 complex stability constant, log ? = 16.5, to be estimated. Determination of the formation constant of Np(V) complexes with SiO32- was not ...
The work identifies the first lattice decoding solution that achieves, in the general outage-limited MIMO setting and in the high-rate and high-SNR limit, both a vanishing gap to the error-performance of the (DMT optimal) exact solution of preprocessed lattice decoding, as well as a computational complexity that is subexponential in the number of codeword bits. The proposed solution employs lattice reduction (LR)-aided regularized (lattice) sphere decoding and proper timeout policies. These performance and complexity guarantees hold for most MIMO scenarios, all reasonable fading statistics, all channel dimensions and all full-rate lattice codes. In sharp contrast to the above manageable complexity, the complexity of other standard preprocessed lattice decoding solutions is shown here to be extremely high. Specifically the work is first to quantify the complexity of these lattice ...
A number of amines can be employed for all volatile treatment (AVT) of steam generator (SG) systems of nuclear power reactors. These amines form complexes with Cu{sup 2+} and Ni{sup 2+} ions which come into water due to corrosion. The redox reactions of a number of Cu(II)-AVT amine complexes and the stability of the transient species formed have been studied by pulse radiolysis technique. Rate constants for the reaction of e{sub aq}{sup -} with a number of Cu(II)-amine complexes have been determined by following the decay of e{sub aq}{sup -} absorption. Stability of Cu(I)-amine complexes was studied by following the kinetics of the bleaching signal formed at the {lambda}{sub max} of the Cu(II) amine complex. Except for Cu(I)-triethanolamine complex all other Cu(I)-amine complexes were found to be stable. One-electron oxidation of Cu(II) ...
Modification of DNA and double-stranded deoxyoligonucleotides with antitumor 1,2-diamino-cyclohexanedinitroplatinum(II) (Pt-dach) complexes was investigated with the aid of physico-chemical methods and chemical probes of nucleic acid conformation. The three Pt-dach complexes were used which differed in isomeric forms of the dach non-leaving ligand-Pt(1R,2R-dach), Pt(1S,2S-dach) and Pt(1R,2S-dach) complexes. The latter complex has lower antitumor activity than the other two Pt-dach complexes. Pt(1R,2S-dach) complex exhibits the slowest kinetics of its binding to DNA and of the conversion of monofunctional binding to bifunctional lesions. The anomalously slow electrophoretic mobility of multimers of the platinated and ligated oligomers suggests that bifunctional binding of Pt-dach complexes to a d(GG) site within double-stranded ...
The thermodynamics of protonation and europium(III) complex formation with substituted methane diphosphonic acids have been reported recently. These ligands form strong complexes with europium in moderately acidic solutions ((H{sup +}) {ge} 0.1 M), conditions not conducive to complexation by most carboxylate and aminopolycarboxylate ligands. A correlation of log {beta} vs pK{sub a} values for phosphonate and carboxylate ligands is used to explore the effect of ligand structure on complex stability. 5 refs., 1 fig.
Carbalkoxylation of vinyl electrophiles was investigated using platinum complexes. This reaction occurs in two steps: (a) carbonyl insertion of {sigma}-vinyl Pt(II) halides and (b) alcoholysis of vinylic acyl Pt(II) complexes. Alcoholysis of vinylic acyl Pt(II) triflate complexes is investigated kinetically. Vinylic acyl Pt(II) complexes were isolated and characterized. 51 refs., 5 figs., 6 tabs.
The formation and stability constants of the [sup(99m)Tc]PM tetracycline have been investigated by the potentiometric method. The pK value of the complex formed was measured as pK = 5.49 +- 0.19. The spectrophotometric study has been performed on the formation of a complex of Sn(II) and TcO"4"- in the presence of PM Tetracycline. This study shows that Sn(II) forms with PMT a complex at a mole ratio of 1:1. The molar extinction coefficients of the Sn-PMT and [_9_9Tc]PMT complexes have been measured. (author).
Reaction of At(I) with triphenylphosphine, triethylphosphite and tri-n-octylphosphine oxide was investigated in ethanolic solution by means of electromigration. A cationic complex with triphenylphosphine was identified being stable at pH = 1,9 in the concentration range of the ligand between c = 10{sup -5} to 10{sup -3} M. At a higher ligand concentration and at pH>2, the reduction effect of phosphine is superimposed on the complex formation. Complex formation is confirmed by ligand exchange reactions with Br{sup -} and I{sup -}. A comparatively weak complex is formed by triethylphosphite and At(I). No compound is formed by tri-n-octylphosphine oxide and At(I). (orig.).
Reaction of At(I) with triphenylphosphine, triethylphosphite and tri-n-octylphosphine oxide was investigated in ethanolic solution by means of electromigration. A cationic complex with triphenylphosphine was identified being stable at pH = 1,9 in the concentration range of the ligand between c = 10"-"5 to 10"-"3 M. At a higher ligand concentration and at pH>2, the reduction effect of phosphine is superimposed on the complex formation. Complex formation is confirmed by ligand exchange reactions with Br"- and I"-. A comparatively weak complex is formed by triethylphosphite and At(I). No compound is formed by tri-n-octylphosphine oxide and At(I). (orig.).
Al, Ga and In complexing with methylthymol blue (H_6R) purified by gel filtration is studied. in the case of metal excess complexes with the ratio of components M:H_6R=2:1 with #lambda#=587(Al), 590(Ga) and 593 nm(In) appear. In the case of reacting agent excess complexes with the ratio of component 1:1 with #lambda#_m_a_x=480-490 (Al) and 480 nm(Ga, In) appear. The mechanism of complexing reactions is studied. Molar extinction coefficients and stability constants are calculated.
The heavy chain (HC) subunits of the bikunin proteins are covalently attached to a single chondroitin sulfate (CS) chain originating from bikunin and can be transferred to different hyaluronan (HA) molecules by TSG-6/HC2. In the present study, we demonstrate that HCs transferred to HA may function as HC donors in subsequent transfer reactions, and we show that the CS of bikunin may serve as an HC acceptor, analogous to HA. Our data suggest that TSG-6/HC2 link HCs randomly on the CS chain of bikunin, in contrast to the ordered attachment observed during the biosynthesis. Moreover, the results show that the transfer activity is indifferent to the new HC position, and the relocated HCs are thus prone to further TSG-6/HC2-induced transfer reactions. The data suggest that HCs may be transferred directly from HA to HA without the involvement of the bikunin CS chain. The results demonstrate reversibility of the interactions between HCs and ...
Probiotic agents, live microorganisms with beneficial effects for the host, may offer an alternative to conventional antimicrobials in the treatment and prevention of enteric infections. The probiotic agents Lactobacillus plantarum 299v and Lactobacillus rhamnosus GG quantitatively inhibited the adherence of an attaching and effacing pathogenic Escherichia coli to HT-29 intestinal epithelial cells but did not inhibit adherence to nonintestinal HEp-2 cells. HT-29 cells were grown under conditions that induced high levels of either MUC2 or MUC3 mRNA, but HEp-2 cells expressed only minimal levels of MUC2 and no MUC3 mRNA. Media enriched for MUC2 and MUC3 mucin were added exogenously to binding assays and were shown to be capable of inhibiting enteropathogen adherence to HEp-2 cells. Incubation of L. plantarum 299v with HT-29 cells increased MUC2 and MUC3 mRNA expression levels. From these in vitro studies, we propose the hypothesis that the ability of probiotic agents ...
This study aimed to reveal that severe disturbance of attachment relationship with primary care-giver can affect functional and anatomical brain development by measuring cerebral perfusion on "9"9"mTc-ECD brain SPECT and correlative MRI. We included 18 children aged 31 to 76 months who met the diagnostic criteria of RAD as defined in DSM-IV and ICD-10 and SSP and CARS. "9"9"mTc-ECD SPECT was performed using CERASPECT. MRI was performed in all patients. SPECT data were visually assessed. 15 of 18 children had abnormal perfusion on SPECT, revealing decreased perfusion of Lt.thalamus (7/15) and Rt.thalamus (3/15), and bilateral thalami (5/15). Perfusion of basal ganglia was decreased in 8 children. Decreased perfusion of Lt. parietal area was seen in 2. Whereas, all patients had normal MR findings. Perfusion abnormalities involving thalamus, BG in most children with RAD were found in this study. These results suggest that brain development of infant could be impeded ...
Experiments on manganese removal using an aerated granular filter with mean particle size of 3.68 mm and 5.21 mm anthracite were conducted at a filtration rate of 100 m d{sup -1}. Air, with a rate of 0 to 366 m d{sup -1}, was supplied through nozzles positioned 100 mm above the filter column bottom. From the experiments that were conducted, it was found that manganese removal is completed at a pH of 9.6 or above. In addition, the oxidation and removal rate of dissolved manganese were expressed as a first-order reaction. The smaller the filter media particles were, the higher the manganese removal efficiency was. The aeration rate of dissolved oxygen in raw water is sufficient for the manganese removal process. The manganese removal rate increased with time due to the catalytic effect of manganese dioxide (MnO{sub 2}) attached to the media. The x-ray diffraction analysis showed that the solids attached to the filter media were not crystalline ...
Macrofouling of cooling-water systems is one of the more significant and costly problems encountered in the nuclear power industry. Both marine and freshwater macroinvertebrates can be responsible for losses in plant availability because of plugged intakes and heat transfer equipment. There is a greater diversity of macrofouling organisms in marine waters than in fresh waters. Marine macrofouling organisms include barnacles, mollusks, bryozoans, and hydroids. Barnacles are crustaceans with feathery appendages, which allow them to attach to a variety of surfaces. They are a major cause of severe macrofouling because they can remain attached even after death. The major freshwater macrofouling organisms include the Asiatic Clam (Corbicula fluminea) and the newest freshwater macrofouler, the Zebra Mussel (Dreissena polymorpha). The introduction of the Zebra Mussel into the Great Lakes has created economic and ecological problems that will not ...
This patent describes a solar heater freeze protection valve apparatus comprising in combination: a valve housing; a remote sensor operatively connected to the valve housing from a remote position, the remote sensor including a bulb containing a liquid adapted to compress and expand with the temperature adjacent the bulb; a piston located in the valve body and slidable responsive to expansion and contraction of the liquid in the remote sensor; a first valve element located in the valve housing and attached to the valve piston for movement; a second valve element located in the valve housing and attached to the housing; a first valve seat in the second valve element forming an opening; a second valve seat positioned in a water passageway to allow the flow of fluid when the second valve element is in an open position and to cut off the flow of fluid when the second valve element is in a closed position. Liquid in a solar heater flows at ...
Abstract: We tested the effects on the early-stage wound healing of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanofiber matrices cultured with hair follicular cells. PHBV only, PHBV/collagen, and PHBV/gelatin at a 7/3 weight ratio were produced by electrospinning, and their in vitro cell culture and in vivo wound healing as biological dressings were examined. In cell attachment and growth on matrices, dermal sheath (DS) cells attached to hydrophilic PHBV/collagen and PHBV/gelatin faster than hydrophobic PHBV at the early incubation stage (up to 6 h). From 6- to 24-h incubation, PHBV/collagen showed the best results in cell culture. Furthermore, PHBV/collagen cocultured for 3-5 days with DS and epithelial outer root sheath (ORS) cells expressed more extracellular materials, such a...
Exercise training associated with robust conditioning can be useful for the study of molecular mechanisms underlying exercise-induced cardiac hypertrophy. A swimming apparatus is described to control training regimens in terms of duration, load, and frequency of exercise. Mice were submitted to 60- vs 90-min session/day, once vs twice a day, with 2 or 4% of the weight of the mouse or no workload attached to the tail, for 4 vs 6 weeks of exercise training. Blood pressure was unchanged in all groups while resting heart rate decreased in the trained groups (8-18%). Skeletal muscle citrate synthase activity, measured spectrophotometrically, increased (45-58%) only as a result of duration and frequency-controlled exercise training, indicating that endurance conditioning was obtained. In groups which received duration and endurance conditioning, cardiac weight (14-25%) and myocyte dimension (13-20%) increased. The best conditioning protocol to promote physiological ...
The growth kinetics constants and concentration of active attached biomass in an anaerobic fluidized bed which decomposes acetic, propionic and butyric acid were estimated. The mixture of above mentioned fatty acids was supplied to the fluidized bed in the range of hydraulic retention time (HRT) from 0.25 to 2 days. After the effluent reached in a steady state in quality, batch experiments were conducted separately with each fatty acid as a substrate in order to investigate the decomposition characteristics of each substrate by attached biomass. In order to estimate the parameter values of the growth kinetics of the bacteria, batch experiments were also conducted under the completely mixed condition using detached biomass from a support material. The changes of fatty acid concentrations with time were clearly expressed with the Monod growth model. Maximum specific substrate decomposition rates and saturation constants, and active biomass ...
Ammonia adsorption on the external surface of C_3_0B_1_5N_1_5 heterofullerene was studied using density functional calculations. Three models of the ammonia-attached C_3_0B_1_5N_1_5 together with the perfect model were optimized at the B3LYP/6-31G"* level. The optimization process reveals that dramatic influences occurred for the geometrical structure of C_3_0B_1_5N_1_5 after ammonia adsorption; the B atom relaxes outwardly and consequently the heterofullerene distorts from the spherical form in the adsorption sites. The chemical shielding (CS) tensors and nuclear quadrupole coupling constants of B and N nuclei were calculated at the B3LYP/6-311G"*"* level. Our calculations reveal that the B atom is chemically bonded to NH_3 molecule. The B atom in the NH_3-attached form has the largest chemical shielding isotropic (CSI) value among the other boron nuclei. The C_Q parameters of B nuclei at the interaction sites are significantly decreased after ...
Dissolved humic substances (humic and fulvic acids) occur in surface waters and groundwaters in concentrations ranging from less than 1 mg(C)/L to more than 100 mg(C)/L. Humic substances are strong complexing agents for many trace metals in the environment and are also capable of forming stable soluble complexes or chelates with radionuclides. Concentrations of humic materials as low as 1 mg(C)/L can produce a detectable increase in the mobility of some actinide elements by forming soluble complexes that inhibit sorption of the radionuclides onto rock materials. The stability of trace metal- or radionuclide-organic complexes is commonly measured by an empirically determined conditional stability constant (K'), which is based on the ratio of complexed metal (radionuclide) in solution to the product concentration of uncomplexed metal and humic complexant. ...
Infant mice were used to measure the amount of fluid accumulation (enterosorption) in the intestinal tract after oral inoculation of a porcine strain of enteropathogenic Escherichia coli (K88-+, Ent-+). Significant reduction in the amount of fluid found in the intestinal tract was observed if the mice were first inoculated with a K88-possessing, non-enterotoxigenic strain of E. coli. The protection provided is thought to be due to specific competition for attachment sites on cells of the small intestine. PMID:1095492
Generally, Hardening and irradiated brominating phenomena are occurred in the reactor vessel under operation conditions by atomic cavities and creation of impurity atoms which are led by high fast neutron flux. To assure the mechanical integrity of pressure vessel until the end of power plant life after monitoring the sample specimens on the vessel inside, a series of tests is performed over the retrieved surveillance capsule to examine the changes according to the plant operation in accordance with regulations. Monitoring surveillance capsules attached to neutron shield wall of outer core are consists of impact sample, tensile sample and temperature monitor
We show that to explain the growth of the citation network by preferential attachment (PA), one has to accept that individual nodes exhibit heterogeneous fitness values that decay with time. While previous PA-based models assumed either heterogeneity or decay in isolation, we propose a simple analytically treatable model that combines these two factors. Depending on the input assumptions, the resulting degree distribution shows an exponential, log-normal or power-law decay, which makes the model an apt candidate for modeling a wide range of real systems.
Describes performance of excavator teeth manufactured with a new hard alloy. The alloy was developed by the Donetskii Politeknicheskii Institute. Its composition consists of a high-chromium steel with a larger amount of titanium than serial alloy, and a nitrogen additive. Trial tests of new alloy teeth were carried out in the Severnyi and Vershinskii coal surface mines. The teeth were attached to EhRP, EhPG and EhR bucket wheel excavators. Abrasive wear of 129 experimental teeth and 134 serial teeth was compared for different excavation conditions. Test results are tabulated; advantages of the new experimental teeth are listed. 3 refs.
The purpose of-this planning guide is to present the process used to identify, document, and control PFP Stabilization and Deactivation Project interfaces. Revisions to this document will include, as attachments, the most recent version of the Project Interface Management List. A preliminary Interface Management List is included in Appendix A. This document is intended be a Project owned management tool. As such, this document will periodically require revisions resulting from improvements of the information, processes, and techniques as now described. For most revisions that suggest improved processes, PFP management approval is all that will be required.
Researchers are developing polymer-based coating systems to reduce scaling and corrosion of air-cooled condensers that use a geothermal fluid spray for heat transfer augmentation. These coating systems act as barriers to corrosion to protect aluminum fins and steel tubing; they are formulated to resist the strong attachment of scale. Field tests have been done to determine the corrosion and scaling issues related to brine spraying and a promising organometallic polymer has been evaluated in salt spray tests.
Purpose: To prevent evaporization stills against corrosion due to radioactive liquid wastes. Constitution: Microwaves are supplied from a microwave generator by way of a wave guide tube and through a microwave permeation window to the inside of an evaporatization still. A matching device is attached to the wave guide tube for transmitting the microwaves in order to match the impedance. When the microwaves are supplied to the inside of the evaporization still, radioactive liquid wastes supplied from a liquid feed port by way of a spray tower to the inside of the evaporization still is heated and evaporated by the induction heating of the microwaves. (Seki, T.).
A manipulator for checking the inside of a vertical, flange-shaped collector of a horizontal steam generator consists of a rotating mast with bearings at the top and bottom ends with a support that can be moved along the length of the mast for the checking system mountings. The support is propelled by a drive spindle placed parallel to the mast with its drive head bearing in the support and locked into a toothed rack attached to the mast. The checking system mountings are fitted in or on the walls of the support and are very close to the box-shaped support. Their retractable arms are hinged.
Scientists at JPL have developed chemical and biological techniques using microspheres filled with drugs, electron-opaque metals, or radioactive, fluorescent, magnetic or electrically charged materials to label specific groups of cells. Synthetic polymeric microspheres are coupled with specific antibodies to form reagents called immunomicrospheres, which can seek out and attach themselves to any specific group of cells. These cell-labeling techniques, therefore, open new avenues not only to the basic study of cells but also to the diagnosis and treatment of many diseases, including cancer.
An insulated letter drop plate comprises a back plate having an opening for the mail having two hinges at its upper part to attach a cover to; a frame for retaining a first insulation around its perimeter and around the opening; and suitable insulation. This back plate is also provided with an upper curved extension to cover and conceal said hinges. A cover is provided with two complementary hinges to be articulated with the first hinges on the back plate, and with a frame around the perimeter for the retention of a second insulation. A wire joins the first and second hinges, and a coil spring on the wire keeps the cover normally closed.
Large scale steam storage power generation, one of the new energy storage systems for the future of inflexible electric power sources consisting of nuclear and coal power plants has been studied on the subjects of the systems to be attached to coal and nuclear power units, of the definition of storage efficiency and of the vertical steam storage vessel technology. Steam storage power generation may be hopeful for its higher efficiency similarly defined as of pumped storage plants while high temperature heat storage and the internal structure of large vertical steam storage vessel (accumulator) need to be developed.
Large scale steam storage power generation, one of the new energy storage systems for the future of inflexible electric power sources consisting of nuclear and coal power plants has been studied on the subjects of the systems to be attached to coal and nuclear power units, of the definition of storage efficiency and of the vertical steam storage vessel technology. Steam storage power generation may be hopeful for its higher efficiency similarly defined as of pumped storage plants while high temperature heat storage and the internal structure of large vertical steam storage vessel (accumulator) need to be developed. (author).
In the present study, a subcooled boiling loop with an annular flow on the electrically heated rod was used to make an experimental approach to investigate the effects of induced instability by the subcooled boiling on vibration of the rod in different subcooled conditions. The results show the intensive subcooled-boiling-induced vibration (SBIV) which is highly depend on dynamic force generated by fast vapor bubbles growth and collapse whilst they still attach to, or slide along, the heating surface at high loading heat fluxes. These behaviors were strongly influenced by the conditions of subcooling temperature, flow rate and linear power density. (author)
The importance that must be attached to the phenomenon of stress corrosion cracking of austenitic alloys is emphasized. The relation between chemical composition of various alloys and their sensitivity to cracking is shown with particular reference to the behaviour of Alloy 800. The different effects of alkaline anc chloride environments are discussed. Studies are reported of the general corrosion of Alloy 800 and other alloys in an environment representative of the primary coolant of PWR reactors; and of the behaviour of various alloys (including Alloy 800) in the conditions envisaged for their use for steam generators with superheat up to about 550 deg.C. (U.K.).
It is important to accurately estimate the effects of strong earthquake motions on the basemat uplift behavior and structural responses for the seismic design of nuclear power plant buildings. In this paper, an analysis model which describes the soil part using the 3 dimensional FEM was proposed to be used when the ground contact ratio is low, and the validity of this model was confirmed. Furthermore, investigations using the model were carried out where the attaching force under the basemat was taken into account, in order to more realistically estimate the basemat uplift behavior. The effects in the case of the building being embedded were also investigated.
It is important to accurately estimate the effects of strong earthquake motions on the basemat uplift behavior and structural responses for the seismic design of nuclear power plant buildings. In this paper, an analysis model which describes the soil part using the 3 dimensional FEM was proposed to be used when the ground contact ratio is low, and the validity of this model was confirmed. Furthermore, investigations using the model were carried out where the attaching force under the basemat was taken into account, in order to more realistically estimate the basemat uplift behavior. The effects in the case of the building being embedded were also investigated.
An actuating mechanism of a mine combine is proposed. It includes a rotating platform in a vertical plane on which by hinges with the possibility of rotation parallel to the plane of the platform there are handles with cutting drums and a mechanism for extension of the handle which has hydraulic cylinders. With a decrease in load on the hinges of the handles from bending forces, on the platform between the front edge of the platform and the site of attachment of the handle hinges there are openings. Each handle has a support projection which is placed in this opening with the possibility of movement. A clamp plank is installed on it which covers the opening. The distance from the center of the projection support to the axis of the corresponding hinge is greater than the height of embedding of this hinge into the platform.
A sifter is proposed, which includes a frame, a sifting surface in the form of transverse grates, positioned on a hinge and lever mechanism, one of the axis of the hinges of which is connected with the frame and the other, with a movable frame, which is adjoined with the drive pushrod for changing the width of the slots between the grates. To increase the effectiveness of initial classification through periodic cleaning of the sifting surface, the hinge and lever mechanism is made in the form of a multiple parallelogram, while the grates are formed by one of the peripheral axes of the hinges of the parallelogram. The movable frame is installed with the capability of attachment to different axes of the parallelogram hinges. The frame is U shaped.
We have developed a new type personal dosemeter by using a B-10 doped silicon p-n junction detector with a polyethylene radiator and a polyethylene moderator. The purpose of this study was to develop a real time neutron dosemeter with a nearly flat response in the energy range from thermal to 15 MeV and low angular dependence to the incident neutron direction. The neutron response of the dosemeter was obtained with the Monte Carlo calculation and the monoenergetic neutron experiment in a free air field and also under a condition attached on a phantom.
To evaluate a dose conversion factor from the `Working Level of Month` (WLM) of radon to the absorbed dose (mGy), the quality of radon and its progeny was assessed, and exposures controlled for each deposition region were planed as follows: 1) exposure of radon gas to the entire respiratory tract, 2) exposure of `unattached` fractions to the upper respiratory tract, 3) exposure of `attached` fractions onto ultrafine particles to the deep lung, 4) exposure of `attached` fractions onto fine particles to the lower respiratory tract, 5) exposure of `attached` fractions onto coarse particles to the upper respiratory tract. In this preliminary study, a prototype exposure system of radon and its progeny for small rodents was designed. A whole body exposure chamber with a volume of about 0.5 m{sup 3} was used, which it held 20 rats. The aging and mixing chamber separated by the exposure chamber had a volume of about 1 m{sup 3}. As ...
A feasibility study test and 3 field trials were performed at Darlington NGS in 1996, 1999 and 2000 on ABB LP turbines. The scope of these trials was to commission in-situ automatic phased array systems capable to inspect blade roots and rotor steeples of L-0 and L-1 rows. GE disk-blade rim attachments were inspected at Bruce B nuclear station, in fall of 1999. The automated ultrasonic phased array technology is capable of high-speed rate and reliable detection and sizing. The capability demonstration was performed on mock-ups and reference blocks, using EDM notches. A custom built UT simulation software: Imagine 3D interfaces with SimScan to generates the spreadsheets/charts with target and probe coordinates and ultrasonic path and angles (refracted and skew) to hit the reference target. Examination of L-0 blade and rotor steeple grooves was performed with 2 phased array systems under networking. Data analysis was done in near-real time. Manual and automatic ...
The phosphate complexation of Np(V) is investigated in the pH range from 6.4 to 10.0 in 0.1 M NaClO_4 at 22#+-#2 C by absorption spectroscopy. The formation of two phosphate complexes is confirmed by spectroscopic speciation: NpO_2HPO"-_4 at 988.8 nm and NpO_2PO"2"-_4 at 993.6 nm with molar extinction coefficients of 251#+-#8 and 201#+-#11 1/mol cm, respectively. The complexation constants are determined to be log #beta# = 2.54#+-#0.02 for NpO_2HPO"-_4 and log #beta# = 6.33#+-#0.08 for NpO_2PO"2"-_4. The competition of the phosphate complexation with the carbonate complexation is demonstrated by speciation calculation under different geochemical conditions. (orig.).
Complex fluids have long posed a significant challenge in our ability to characterize and model fluid properties. Here, we consider complex fluids to be mixtures with many components that can differ significantly in polarity and polarizability. The penultimate complex fluid is crude oil, although many other fluids such as finished fuels are also highly complex. We have recently introduced a measurement strategy that can simplify these efforts and provides the added potential of linking chemical composition (i.e. analytical) information with physical property information. In addition to chemical characterization, the approach provides the ability to calculate thermodynamic and transport properties for such complex heterogeneous streams. The technique is based on the advanced distillation cu...
A variable gene delivery system has been developed based on conjugating chitosan to biotin through a functionalized poly(ethylene glycol) (PEG) spacer, which can be used to further bind different molecules on the outer layer of a polymer/DNA complex by streptavidin (SA)-biotin linkage. In this study, TAT-conjugated SA was used as the model molecule to prove the conjugation function of the prepared complex. In addition, low-molecular-weight poly(ethyleneimine) (PEI) was added into the polymer/DNA complex to increase the transfection efficiency. The results of the luciferase assay show that the transfection efficiency of the prepared complex was significantly correlated with the amount of PEI and was further enhanced when TAT was conjugated to the complex by SA-biotin linkage. Considered to have negligible cytotoxic effects, the variable gene delivery complex ...
Tuberous Sclerosis Complex (TSC) is a neurogenetic disorder caused by loss-of-function mutations in either the TSC1 or TSC2 genes and frequently results in...Full Text Available
The mini-chromosome maintenance proteins Mcm2–7 are essential for DNA replication. They are loaded onto replication origins during G1 phase of the cell cycle to form a pre-replication complex...Full Text Available
The effects of bovine α-globulin (BAG), bovine-ribonuclease serum albumin (BSA-RNase) and polyribonuclease (poly-RNase) complexes on the primary response of rodents to sheep erythrocytes have...Full Text Available
We have developed a method to extract and separate phytochelatins (PCs)—metal(loid) complexes using parallel metal(loid)-specific (inductively coupled plasma-mass spectrometry) and organic-specific...Full Text Available
Genetic defects in the dystrophin-associated protein complex (DAPC) are responsible for a variety of pathological conditions including muscular dystrophy, cardiomyopathy, and vasospasm. Conserved DAPC...Full Text Available
Platinum(II) complexes (1-4) with bidentate N,Nprime-ligands, O,Oprime-dialkyl esters (alkyl = ethyl, n-propyl, n-butyl and n-pentyl), of (S,S)-ethylenediamine-N,Nprime-di-2-(4-methyl)pentanoic acid were synthesized and characterized by IR, 1H NMR and 13C NMR spectroscopy and elemental analysis. DFT calculations were performed for the complexes and it was found that only one diastereoisomer could be formed. Cytotoxic activity of complexes 1-4 was determined against chronic lymphocytic leukemia cells (CLL) and compared to the activity of ligand precursors L12HCl-L42HCl and corresponding palladium(II) complexes, [PdCl2L] (L = L1-L4). The complexes were found to exhibit significantly higher antitumor activities than cisplatin on CLL cells. Cytotoxic effect of platinum(II) complexes on CLL cel...
We ran a comparative analysis of all patients for whom a positive culture of Mycobacterium tuberculosis complex was available between April 2004 and October 2005 and whose HIV serology...Full Text Available
We show here sodium ion cycling between complex I from Klebsiella pneumoniae and the F1F0 ATP synthase from Ilyobacter tartaricus in a reconstituted...Full Text Available
A general method is described to sequester peptides containing azides from complex peptide mixtures, aimed at facilitating mass spectrometric analysis to study different aspects of proteome...Full Text Available
Yeast Sir2 deacetylase is a component of the silent information regulator (SIR) complex encompassing Sir2/Sir3/Sir4. Sir2 is recruited to telomeres through Rap1, and this complex spreads into subtelomeric...Full Text Available
Resonance Raman spectra are reported for the organometallic phenyl-FeIII complexes of horse heart myoglobin. We observed the resonance enhancement of the ring vibrational modes of the bound phenyl group....Full Text Available
We use high-density single nucleotide polymorphism (SNP) genotyping microarrays to demonstrate the ability to accurately and robustly determine whether individuals are in a complex genomic DNA mixture....Full Text Available
The main aim of the present study was to evaluate potential of ternary complexation (comprising of drug, cyclodextrin and polymer) as an approach for taste masking. For this purpose famotidine with...Full Text Available
Rapamycin inhibits the mTOR (target of rapamycin) pathway and extends lifespan in multiple species. The tuberous sclerosis complex (TSC) protein is a negative regulator of mTOR. In humans, loss of the...Full Text Available
It has been discovered that iron(III) chloride complexes supported on activated charcoal oxidize phosphine under normal conditions. The process accelerates as the concentration of the chloride ions and the proton acid increases.
The article gives a brief description of the state of the nuclear power engineering in Ukraine and in the world as of today. There are basic organizational and practical actions on scientific and technical maintenance of the Ukraine nuclear power complex presented in the article.
The number of nuclear pore complexes (NPCs) in individual nuclei of the yeast Saccharomyces cerevisiae was determined by computer-aided reconstruction of entire nuclei from electron...Full Text Available
Endosomal sorting complexes required for transport (ESCRTs) are heteromeric protein complexes required for multivesicular body (MVB) morphogenesis. ESCRTs I, II, III and III-associated are ubiquitous...Full Text Available
A process for the recovery of nitrilotriacetic acid values from solutions containing polyvalent metal complexes of nitrilotriacetic and the decomposition products thereof is described, the process being characterized by the addition to such solutions of sufficient strong acid to dissociate the complex under conditions to precipitate the nitrilotriacetic acid.
Photosynthetic antenna complexes capture and concentrate solar radiation by transferring the excitation to the reaction center that stores energy from the photon in chemical bonds. This process occurs...Full Text Available
Sheep choroid plexus cells infected with visna virus produce intracytoplasmic viral ribonucleoprotein complexes with sedimentation values of 120S to 200S and buoyant densities of 1.29 to 1.32 g/cm3....Full Text Available
The bulky octahedral complex, Rh(bpy)2chrysi3+ (chrysi = 5, 6- chrysenequinone diimine), binds single base mismatches in a DNA duplex with micromolar binding affinities...Full Text Available
Major histocompatibility complex (MHC) genes are highly polymorphic components of the vertebrate immune system, which play a key role in pathogen resistance. MHC genes may also function as odour-related...Full Text Available
The Carassius auratus complex in natural populations includes diploid triploid and polyploidy individuals. Diploid individuals belong to the species Carassius auratus...Full Text Available
The genetic architecture of complex traits underlying physiology and disease in most organisms remains elusive. We still know little about the number of genes that underlie these traits, the magnitude...Full Text Available
The presence of DNA-anti-DNA complexes in sera from patients with systemic lupus erythematosus (SLE) was investigated by two new radioimmunoassays (RIA) developed for this purpose and by measuring the...Full Text Available
Metazoan life cycles can be complex in different ways. A number of diverse phenotypes and reproductive events can sequentially occur along the cycle, and at certain stages a variety of developmental...Full Text Available
Adopting the approach taken with New Caledonian crows (Corvus moneduloides), we present evidence of design complexity in one of the termite-fishing tools of chimpanzees (Pan...Full Text Available
Designer cellulosomes are precision-engineered multienzyme complexes in which the molecular architecture and enzyme content are exquisitely controlled. This system was used to examine enzyme cooperation...Full Text Available
We report a case of a female patient who was operated at the third relapse of an atrial myxoma caused by Carney complex. The difficult operation was performed without any complications despite extensive...Full Text Available
Endogenous immune complexes present in sera from 10 different patients with systemic lupus erythematosus (SLE) in an active phase were allowed to bind to Raji cells; the ability of intact complement...Full Text Available
BackgroundThe genomic organisation of the Major Histocompatibility Complex (MHC) varies greatly between different vertebrates. In mammals, the classical MHC consists of a large number...Full Text Available
The function of the hyolingual complex in three odontocete species was investigated to compare adaptations of divergent feeding strategies, suction and ram feeding. Pygmy and dwarf sperm whales, members...Full Text Available
MOM22 is a component of the protein import complex of the mitochondrial outer membrane of Neurospora crassa. Using the newly developed procedure of 'sheltered disruption', we created a heterokaryotic...Full Text Available
This paper is to report a case of multi-ruptured complex pseudoaneurysm confirmed by three-dimensional DSA. Under three-dimensional DSA guidance, the thrombin was injected into lumens in the attempt to cure the pseudoaneurysm. As the result was unsatisfactory, fibrin sealant was used to inject into the lumens again, and good curative effect was obtained. In clinical interventional practice, the incidence of pseudoaneurysm has been steadily increasing and the lesions have become more and more complex. In this paper the authors have discussed the diagnostic and therapeutic methods of complex pseudoaneurysm in order to provide clinical physicians with useful information. (authors)
The absorption, emission and magnetic circular dichroism spectra of the anionic complex (Cp_3Pr. NCS)"- were measured at room and low temperatures. On the basis of these spectra the electronic structure in the f-f range could be derived. The parameters of an empirical Hamiltonian were fitted to the experimentally determined crystal field splitting pattern. Compared with the previously examined neutral Cp_3 Pr.X complexes the quadratic crystal field parameter B_0"2 is considerably reduced.
The first preparation and characterization of the platinum (II) complexes containing five phosphorus ligands are reported herein. The complexes are represented by the formulae (Pt(PP/sub 3/)(P(OR)/sub 3/)Cl/sub 2/, where R = Me or Et, and (Pt(PP/sub 3/)(PEt/sub 3/))Cl/sub 2/. The /sup 31/P spectra of the complexes are presented. 10 references, 2 tables.
Three novel inosine-based dinuclear platinum complexes have been synthesized via a solid-phase strategy. In these compounds, the metal is linked both to the N-7 of the purine nucleus and to the terminal amine group of a hexylamine side chain installed on N-1. Cis- or trans- diamine as well as ethylenediamine ligands are coordinated to platinum along with a chloride. The synthesised complexes were tested against four different human tumor cell lines. One of these complexes proved to be more cytotoxic than cisplatin against the MCF7 cancer cell line in a short-term exposure assay.
... interactive surfaces and interfaces, and 3) the more complex a ... carbonate or calcium phosphate with a thin interface ... diameter) for nerve prosthesis. ...
The phase transition is a performance measure of the sparsity-undersampling tradeoff in compressed sensing (CS). This letter reports, for the first time, the existence of an exact phase transition for the $\\ell_1$ minimization approach to the complex valued CS problem. This discovery is not only a complementary result to the known phase transition of the real valued CS but also shows considerable superiority of the phase transition of complex valued CS over that of the real valued CS. The results are obtained by extending the recently developed ONE-L1 algorithms to complex valued CS and applying their optimal and iterative solutions to empirically evaluate the phase transition.
This Waste Management Plan functions as a management and planning tool for managing waste streams generated as a result of operations at the Idaho CERCLA Disposal Facility (ICDF) Complex. The waste management activities described in this plan support the selected remedy presented in the Waste Area Group 3, Operable Unit 3-13 Final Record of Decision for the operation of the Idaho CERCLA Disposal Facility Complex. This plan identifies the types of waste that are anticipated during operations at the Idaho CERCLA Disposal Facility Complex. In addition, this plan presents management strategies and disposition for these anticipated waste streams.
Consideration is given to results of investigation into thorium complexing with morin (H_2Mor) in extraction systems containing different carboxylic acids as well as different salt background. The obtained data enabled to suggest the method of photometric determination of thorium in the form of Th(HMor)_2Benz_2 different-ligand complex (where Benz-anion of benzilic acid) with 0.25 #mu#g/ml detection limit.
Modern microprocessor-based relays for the protection of the various power system components such as generators, transformers, feeders, and high voltage transmission lines are becoming more sophisticated as increasingly more complex functions and capabilities can be included in the microprocessor. With this increasing complexity, and the increasing complexity of the power system itself, there is even more value in testing the suitability of relaying equipment for the intended applications. This paper reviews the testing philosophy, experience, and capabilities developed at Ontario Hydro over more than 25 years of testing protective relays.
Using the PMR method the interaction of zirconium and hafnium tetrachlorides with tri.tet.butylphenyl ester of 1,2- naphthoquinonediazide (2)-5-sulfonic acid is studied. The formation of MCl/sub 4/xNQD complexes is established, the equilibrium constants and thermodynamic parameters of complexing reaction are determined. The presence of rapid ligand exchange, proceeding according to associative mechanism, is detected. The rate constants and activation energies of the exchange reaction are calculated.
Using the PMR method the interaction of zirconium and hafnium tetrachlorides with tri.tet.butylphenyl ester of 1,2- naphthoquinonediazide (2)-5-sulfonic acid is studied. The formation of MCl_4xNQD complexes is established, the equilibrium constants and thermodynamic parameters of complexing reaction are determined. The presence of rapid ligand exchange, proceeding according to associative mechanism, is detected. The rate constants and activation energies of the exchange reaction are calculated.
Stability constants for uranium-tetracycline complexes were determined by the method of average number of ligands, the method of limiting values, the method of two parameters and the method of weighted least squares. Solvent extraction technique was used to obtain experimental data. (author). 10 refs.; 5 figs.
During the past 3 years, progress was made in elucidating the excited state structures of Pt(diimine)(dithiolate) complexes, while more recent efforts focused on the photochemistry of these complexes and electronic structure of other dithiolate systems. A carbonyl-Ir-maleonitrile dithiolate complex is also studied.
FT-IR spectrum of fulvic acid from wheathered coal of Gongxian is determined using second derivative spectroscopy and the spectroscopic resolution is enhanced. Moreover, FT-IR spectra of the complexes of fulvic acid with Ca"2"+, Ba"2"+, Cu"2"+, Pb"2"+ and UO_2"2"+ under different pH are determined and the nature of the coordination of these complexes is discussed.
The complex formation of astatine(I) cation with diethylene triamine pentaacetic acid (DTPA) and characterization of the complexes were investigated by electromigration in free electrolytes and by gel-chromatography on Sephadex G 25. The conjugation procedure for the production of At-DTPA conjugated polyclonal antibodies is described. (author) 15 refs.; 2 figs.
The complex aspects of high energy physics work are briefly described, and approaches to managing them are discussed. Management of software and data are covered. For managing complexity in experimental physics, the choice of building or buying processor systems is addressed and the issues of compatibility and standardization are discussed. (LEW)
Amphiphilic pincer palladium complexes bearing hydrophilic and hydrophobic side chains on the planar NCN palladium pincer backbone were designed and prepared via the ligand introduction route. The complexes self-assembled under aqueous conditions to form vesicles with bilayer membranes containing palladium species. The catalytic activity of the vesicles in the Miyaura-Michael reaction in water was investigated. PMID:21837316
Conductivity and Hall effect measurements were made in dark and IR-photoexcited p-type ZnTe samples between 77 and 300 K. Acceptor vacancy complexes of activation energies 0.09-0.1 eV were found to be present in the photoexcited samples. Different possible scattering mobilities were considered for both samples to explain the observed hole mobility. In the photoexcited sample a scattering mobility due to vacancy complexes was suggested for the first time to explain the results. The scattering centres were associated with native vacancy complexes segregated at the dislocations sites. The expression for the complex scattering mobility has been deduced using the curve fitting method to be {mu}{sub C}=(6.6x10{sup -11})T{sup 5} e{sup 725/T}. (orig.).
Based on the X-ray crystallographic data of Tc-complexes for brain imaging agents, geometry optimizations in vacuo of TcO-BAT, TcO-MAMA, TcO-L, L-ECD, TcN-BAT and TcN-L, L-ECD complexes are performed with Hartree-Fock method and LANL 2 DZ basis set of G98W program. Then solvation free energy for each Tc-complex mentioned above in water is calculated by polarizable continuum method (PCM) including models of CPCM and IEFPCM. The results show that solvation free energy of Tc-complex is not only an indicator of lipophilicity but also one of the important factors that influence the brain uptake
Complex numbers are an intrinsic part of the mathematical formalism of quantum theory and are perhaps its most characteristic feature. In this article, we show that the complex nature of the quantum formalism can be derived directly from the assumption that a pair of real numbers is associated with each sequence of measurement outcomes, with the probability of this sequence being a real-valued function of this number pair. By making use of elementary symmetry conditions, and without assuming that these real number pairs have any other algebraic structure, we show that these pairs must be manipulated according to the rules of complex arithmetic. We demonstrate that these complex numbers combine according to Feynman's sum and product rules, with the modulus-squared yielding the probability of a sequence of outcomes.
Scandium reacts with 4-(2-pyridylazo)resorcinol in the presence of monocarboxylic acids (X) to form mixed-ligand complexes with a Sc:PAR:x ratio of 1:2:2. The chemical nature of this interaction has been established, and the extraction of these mixed-ligand complexes has also been investigated; stability constants and molar extinction coefficients have been calculated. The values of the latter decrease in the order CH_3COOH > CH_2ClCOOH > CCl_3COOH. The formation and extraction of mixed-ligand complexes in Sc-PAR-HX systems make it possible to increase the sensitivity and selectivity of scandium determination in comparison with the use of the Sc-PAR mono-ligand complex.
Complex I (NADH:ubiquinone oxidoreductase) is the largest enzyme of the mitochondrial respiratory chain. Compared to its bacterial counterpart which encompasses 14-17 subunits, mitochondrial complex I has almost tripled its subunit composition during evolution of eukaryotes, by recruitment of so-called accessory subunits, part of them being specific to distinct evolutionary lineages. The increasing availability of numerous broadly sampled eukaryotic genomes now enables the reconstruction of the evolutionary history of this large protein complex. Here, a combination of profile-based sequence comparisons and basic structural properties analyses at the protein level enabled to pinpoint homology relationships between complex I subunits from fungi, mammals or green plants, previously identified...
Lebers hereditary optic neuropathy (LHON), the most frequent mitochondrial disorder, is mostly due to three mitochondrial DNA (mtDNA) mutations in respiratory chain complex I subunit genes: 3460/ND1, 11778/ND4 and 14484/ND6. Despite considerable clinical evidences, a genetic modifying role of the mtDNA haplogroup background in the clinical expression of LHON remains experimentally unproven. We investigated the effect of mtDNA haplogroups on the assembly of oxidative phosphorylation (OXPHOS) complexes in transmitochondrial hybrids (cybrids) harboring the three common LHON mutations. The steady-state levels of respiratory chain complexes appeared normal in mutant cybrids. However, an accumulation of low molecular weight subcomplexes suggested a complex I assembly/stability defect, which was ...
Since the elucidation of the structure of double helical DNA, the construction of small molecules that recognize and react at specific DNA sites has been an area of considerable interest. In particular, the study of transition metal complexes that bind DNA with specificity has been a burgeoning field. This growth has been due in large part to the useful properties of metal complexes, which possess a wide array of photophysical properties and allow for the modular assembly of an ensemble of recognition elements. Here we review recent experiments in our laboratory aimed at the design and study of octahedral metal complexes that bind DNA non-covalently and target reactions to specific sites. Emphasis is placed both on the variety of methods employed to confer site-specificity and upon the many applications for these complexes. Particular attention is given to the family of complexes ...
Since the elucidation of the structure of double helical DNA, the construction of small molecules that recognize and react at specific DNA sites has been an area of considerable interest. In particular, the study of transition metal complexes that bind DNA with specificity has been a burgeoning field. This growth has been due in large part to the useful properties of metal complexes, which possess a wide array of photophysical attributes and allow for the modular assembly of an ensemble of recognition elements. Here we review recent experiments in our laboratory aimed at the design and study of octahedral metal complexes that bind DNA non-covalently and target reactions to specific sites. Emphasis is placed both on the variety of methods employed to confer site-specificity and upon the many applications for these complexes. Particular attention is given to the family of complexes ...
An inclusion complex between imazalil (IMZ), a selected fungicide, and cyclomaltoheptaose (beta-cyclodextrin, betaCD) was obtained using supercritical fluid carbon dioxide. The best preparation conditions were determined, and the inclusion complex was investigated by means of 1H NMR spectroscopy in aqueous solution and 13C CPMAS NMR spectroscopy in the solid state. Information on the geometry of the betaCD/IMZ complex was obtained from ROESY spectroscopy, while the dynamics of the inclusion complex in the kilohertz range was obtained from the proton spin-lattice relaxation times in the rotating frame, T(1rho) (1H). PMID:14553984
Two transition metal ions (Cu^2^+ and Co^2^+) and two rare earth metal ions (Ce^3^+ and La^3^+) were used as the assisted metal ions, respectively to prepare the transition metal and rare metal assisted Fe bimetallic amidoximated polyacrylonitrile (AO-PAN) fiber complexes. And their coordination configuration and visible light adsorption properties were examined by coordination number determination and UV-vis-DRS. Then the catalytic performance of these complexes was evaluated as the heterogeneous Fenton catalysts in Rhodamine B degradation by changing the nature and dosage of the assisted ions added. The results indicated that the incorporation of the assisted metal ions led to Fe bimetallic AO-PAN complexes with the more unsaturated configurations than Fe monometallic AO-PAN complex due ...
Absorption spectra of the visible I_2 band of I_2 complexes with Et_2O, Et_2S, and Et_2Se in heptane have been measured up to 3300 bar at 25"0C. The equilibrium constants and volume changes accompanying complex formation, the molar extinction coefficients and the absorption maxima have been estimated. The volume changes were found comparable with those estimated from the X-ray data of the I_2 complexes in the crystalline state. The enhancement of the molar extinction coefficient and the blue shift of the visible I_2 band with increasing pressure have been established. The results suggest a decrease in the bond distance between an n-donor and I_2, compared with the spectroscopic properties of the I_2 complex at 1 bar. The decrease has been estimated as 0.008 nm with increasing pressure up to 3300 bar. (author).
The availability of dimeric Pt(I) complexes with bridging bis(diphenylphosphino)methane ligands, (L--L')/sup n+/, presents an opportunity to study the physical properties and reactivity of metal-metal bonds as a function of the ligand trans to it with a minimum of competing variables. Several interesting trends of Pt-P coupling constants with the Pt-L and Pt-Pt bond lengths in Pt(I) dimers, (L--L')/sup n+/, and structurally related Pt(II) complexes are reported here. The data indicate that the Pt-P coupling constants continue to be sensitive indicators of not only the structure and stereochemistry of platinum phosphine complexes but also the electronic and steric influences of the ligand in such complexes, 23 references, 1 figure, 4 tables.
A-posteriori probability (APP) receivers operating over multiple-input, multiple-output channels provide enhanced performance at the cost of increased complexity. However, employing full APP processing over favorable transmission environments, where less efficient approaches may already provide the required performance at a reduced complexity, results in waste of resources (e.g, processing energy/power). Therefore, for slowly varying channel statistics, substantial complexity savings can be achieved by simple adaptive schemes which perform performance tracking and adjust the complexity of the soft output sphere decoder by adaptively setting the related log-likelihood ratio (LLR) clipping value.
Dust particles in a plasma are charged negatively and are subject to various types of forces, including a drag force by plasma particles and a force due to the collective nature of a plasma. Dust particles are found in a sheath in laboratories balanced by the gravitational force and the electric force, while dust particles in space are ubiquitous, including planetary magnetospheres and interstellar space. Because of the novel nature of a complex system involving plasma particles and dust particles in a collective way, the dusty plasma is often called a complex plasma. The complex plasma is characterized by two distinctly different scales in time and in space. The plasma with electrons, ions and neutrals is characterized by the collective motion with a fast time scale and a short wavelength, while the dust particles move in a slow time scale and a long spatial scale. Some fundamental aspects of a complex ...
A new procedure for preparing an 211At-labeled radiopharmaceutical is suggested. The 211At? anion forms a strong bond with the Rh3+ cation incorporated in the complex with a thiother ligand, 1,5,9,13-tetrathiacyclohexadecane-3,11-diol (16-S4-diol). The reaction conditions are optimized with 131I as astatine analog. The complexes are studied by paper electrophoresis, ion exchange, and thin-layer chromatography. The kinetics of the addition of the 131I? anion to Rh(16-S4-diol) and the dependence of the yield of the forming complex 131I-Rh(16-S4-diol) on the temperature, solution acidity, and reactant concentrations are examined. Taking into account the results obtained, the complex 211At-Rh(16-S4-diol) is prepared by adding astatide (211 At?) to equivalent amounts of RhCl3 and the tetrathioe...
New tetradentate N(2)O(2) donor Schiff bases and their mononuclear Co(II), Ni(II), Cu(II), and Pd(II) complexes were synthesized and characterized extensively by IR, (1)H-, (13)C-NMR, mass, ESR, conductivity measurements, elemental and thermal analysis. Specifically the magnetic and electronic spectral measurements demonstrate the octahedral structures of cobalt(II), nickel(II) complexes and square planar geometries of copper(II), palladium(II) complexes. All the ligands and complexes were screened for their in vitro antibacterial activity against two gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus) and two gram-negative bacteria (Escherichia coli, Klebsiella pneumonia). In this study, Pd(II) complexes exhibited potent antibacterial activity against B. subtilis, S. aureus whereas other metal complexes also exerted good activity towards all ...
New oxomolybdenum(V) complexes MoOClL (where LH/sub 2/ = Schiff base) derived from ethanolamine and salicylaldehyde, 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, 5-nitrosalicylaldehyde, 3-ethoxysalicylaldehyde and 2-hydroxy-1-naphthaldehyde have been synthesized and characterised by elemental analyses, conductance, molecular weight, I.R. and electronic spectra and magnetic measurements. The Schiff bases behave as dibasic tridentate ONO donor ligands. The complexes are non-electrolytes and dimers. The complexes exhibit subnormal magnetic moments and are involved in antiferromagnetic exchange with S = 0 ground state. The complexes exhibit electronic spectral bands at ca. 13000 and ca. 17000 cm/sup -1/ due to the transitions dsub(xy)- > dsub(xz,yz) (/sup 2/B/sub 2/- > /sup 2/E) and dsub(xy)- > dsub(x2-y2) (/sup 2/B/sub 2/- > /sup 2/B/sub 1/), respectively. The ..nu..(Mo = O) frequency of ...
New oxomolybdenum(V) complexes MoOClL (where LH_2 = Schiff base) derived from ethanolamine and salicylaldehyde, 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, 5-nitrosalicylaldehyde, 3-ethoxysalicylaldehyde and 2-hydroxy-1-naphthaldehyde have been synthesized and characterised by elemental analyses, conductance, molecular weight, i.r. and electronic spectra and magnetic measurements. The Schiff bases behave as dibasic tridentate ONO donor ligands. The complexes are non-electrolytes and dimers. The complexes exhibit subnormal magnetic moments and are involved in antiferromagnetic exchange with S = 0 ground state. The complexes exhibit electronic spectral bands at ca. 13000 and ca. 17000 cm"-"1 due to the transitions dsub(xy)->dsub(xz,yz) ("2B_2->"2E) and dsub(xy)->dsub(x2-y2) ("2B_2->"2B_1), respectively. The #nu#(Mo=O) frequency of the complexes is observed in the ...
Absorption spectra of the CT bands of I_2 complexes with Et_2O, Et_2S, and Et_2Se in heptane have been measured up to 4400 bar at 25"0C. The equilibrium constants and the volume changes accompanying complex formation, and the molar extinction coefficients and absorption maxima have been estimated. The volume changes were comparable with those estimated by the visible I_2 bands and by the X-ray data of the I_2 complexes in the crystalline state. In the CT bands of Et_2S-I_2 and Et_2Se-I_2 complexes inversion of shift from red to blue has been observed with increasing pressure though the CT band of Et_2O-I_2 complex shifted only through red. This inversion appears to be characteristic of the strong CT complex. Enhancement of the molar extinction coefficient of the CT band has been found with increasing pressure suggesting enhancement of the CT interaction between ...
No-carrier-added astatine radionuclides produced in the {sup 7}Li-irradiated lead matrix were separated from bulk lead nitrate target by complexing At with insulin, followed by dialysis. The method offers simultaneous separation of At from lead as well as its complexation with insulin. The At-insulin complex might be a potential radiopharmaceutical in the treatment of hepatocellular carcinoma. The stability of At-insulin complex was checked by dialysis against deionized water and Ringer lactate (RL) solution. It has been found that the half-life of At-insulin complex is about {approx}12 h, when dialyzed against deionized water and is only 6 h, when dialyzed against RL solution having the same composition as blood serum. The 6 h half-life of this Insulin-At complex is perfect for killing cancer cells from external cell surfaces as the half-life of internalization ...
No-carrier-added astatine radionuclides produced in the "7Li-irradiated lead matrix were separated from bulk lead nitrate target by complexing At with insulin, followed by dialysis. The method offers simultaneous separation of At from lead as well as its complexation with insulin. The At-insulin complex might be a potential radiopharmaceutical in the treatment of hepatocellular carcinoma. The stability of At-insulin complex was checked by dialysis against deionized water and Ringer lactate (RL) solution. It has been found that the half-life of At-insulin complex is about #approx#12 h, when dialyzed against deionized water and is only 6 h, when dialyzed against RL solution having the same composition as blood serum. The 6 h half-life of this Insulin-At complex is perfect for killing cancer cells from external cell surfaces as the half-life of internalization of ...
A new method of administration of an opioid was recently registered: fentanyl transdermal (brand name: Durogesic), intended particularly for the indication range 'pain in cancer'. Fentanyl is lipid-soluble so that deposition in the skin takes place and the biological half-life is approximately 20 hours after removal of the plaster. It is safe to start on a basis of an equianalgesic conversion of 100:1 in relation to oral morphine, although this may entail some risk of fentanyl under dosage. The dose adjustment time is 12-24 hours before a constant fentanyl level is reached; therefore, after attaching the first sticking plaster, the original morphine dose should be continued for another 12 hours. In addition, the patient may, if necessary, be given supplementary morphine preferably as a short-acting drug. There seems to be no clear indication for transdermal fentanyl either in neuropathic pain or in chronic benign pain. PMID:9221362
The multiple responses of fishes to changes in dissolved oxygen saturations have been studied widely in the laboratory. In contrast only few studies have included field observations. The objective of the present study was to evaluate the performance of a novel acoustic dissolved oxygen transmitter for field biotelemetry. The results demonstrated that the output of the transmitter was unaffected by three different temperatures (10 to 30 degrees C) and described the dissolved oxygen saturation with high accuracy (r(2) > 0.99) over the entire range of 0 to 191% saturation. The response time (>= 90% of end value) of the transmitter was 12 s both in terms of decreasing (100 to 0%) and increasing (0 to 100%) oxygen saturations. When externally attached to fishes the present findings support the use of the transmitter for reliable dissolved oxygen measurements on individuals living in environments that may change both temporally and spatially with regard to ambient ...
Measurements of the retention of /sup 47/Ca and of /sup 203/Pb were made following their administration by intravenous injection. Translocation to bone was measured by ..gamma.. counting the feet of subjects. Uptake by bone of /sup 203/Pb was comparatively slow and extrapolation to the whole skeleton indicated that 20% of the dose has been taken up within 20 days. By time, a similar fraction of the dose has been excreted in urine. Uptake by bone of /sup 47/Ca was about 1.5-2 times the amount excreted in urine. Both the uptake by bone, and its excretion in urine, were more rapid than that of /sup 203/Pb due to the greater attachment of the latter to red blood cells. However, the plasma clearance rate for Pb, like that of Sr, was greater than that of Ca.
A catalytic converter of a ceramic monolith honeycomb substrate, coated with a washcoat of catalyst and attached to a natural gas/diesel dual fuel engine was simulated and studied experimentally. The paper describes the application of one-dimensional finite element model for the transient and steady state operation. Laminar flow was approximated using a dispersed plug flow model, and chemical kinetics were simulated using LHHW (Langmuir/ Hinshelwood/ Hougan/ Watson) type expressions. Simulation results were compared with experimental results for heating and cooling cycles which resulted from speed and load changes on the engine. The comparison showed a maximum difference between the two sets of emission levels of about 10 per cent, showing that the one-dimensional model is acceptable model for this dual fuel engine converter combination. 50 refs., 3 tabs., 13 figs.
This paper presents an innovative way in which university education can help pre-service teachers become better problem-solvers. The central idea is to use the ?Technology Fair?? as a means for promoting pre-service teachers pedagogical content knowledge about technological problem solving skills. This innovation is supported with results from a study carried out in autumn 2004. The purpose of the study was to investigate the influence of a procedure of working with primary school children to complete and present a technology fair project, on the educational value and meanings attached to problem solving skills by pre-service teachers. Pre-tests, mid-test and post-tests were administered to the pre-service teachers before, during, and after the preparation of the technology fair, respectiv...
In this study, the shear viscosities of wood?plastic composites (WPC)/supercritical CO2 (sc-CO2) solutions at different die temperatures and sc-CO2 contents were measured by a slit die attached on a single-screw extrusion system. A theoretical model based on the Carreau-Yasuda model and Arrhenius equation was then developed to describe the shear-thinning behavior of the WPC/sc-CO2 solution. This model was incorporated into a finite element method software, POLYFLOW, to simulate the pressure and velocity field of WPC/sc-CO2 solution flowing through a foaming die. Based on the simulation results, the pressure drop rate and the location of the supersaturation point were estimated to investigate the cell nucleation. The saturation pressure of sc-CO2 in WPC was determined by a magnetic suspensi...
The effects of vibration isolation of the new type of mechanical damper applied to a single-degree-of-freedom system and a simple beam are discussed numerically and experimentally. The damper is composed of a ball screw, a flywheel and centrifugal brakes, and possesses nonlinear characteristics. The Continuous System Simulation Language is used for the digital simulations of the nonlinear vibration systems. The results may be summarized as follows: (1) The damper is effective for suppressing the amplitude of the single-degree-of-freedom system as well as of the beam at the point of attachment of the damper, at the resonances. (2) The damper approaches a snubber for smaller values of lead L of the ball screw (or larger values of moment of inertia J of the flywheel), and acts like a damper whose damping force is proportional to the square of the velocity for larger values of L (or smaller values of J). (author).
A renewed interest in chemical fractionation of soil organic matter (SOM) originates from the premise that it enables to isolate labile SOM from SOM protected through mineral binding and recalcitrant SOM. Both selective removal of labile non-bound SOM through oxidation or hydrolysis as well as selective removal of minerals and attached SOM are often applied. Molecular-level SOM characterization by means of temperature resolved Pyrolysis-Field Ionization Mass Spectroscopy analysis (Py-FIMS) was used here as an approach to obtain insight into the fate of SOM upon wet chemical treatment with regard to composition and thermal stability. The applied sequential chemical treatment with 6% NaOCl and 10% HF yielded similar sizes in stable SOM fractions between sandy semi-native heathland and cultiv...
An experimental and modelling study was performed for a reverse flow catalytic converter attached to a natural gas/diesel dual fuel engine. The catalytic converter had a segmented ceramic monolith honeycomb substrate and a catalytic washcoat containing a predominantly palladium catalyst. A one-dimensional single channel model was used to simulate the operation of the converter. The kinetics of the CO and methane oxidation followed first-order behaviour. The activation energy for the oxidation of methane showed a change with temperature, dropping from a value of 129 to 35 kJ/mol at a temperature of 874 K. The reverse flow converter was able to achieve high reactor temperature under conditions of low inlet gas temperature, provided that the initial reactor temperature was sufficiently high. (author)
Research on and with ethnic minority students is characterised by a growing international literature that privileges 'liberal multiculturalism' as a lens through which to understand their experiences, yet ethnic diversity is constructed and responded to in many societies that are not underpinned by liberal democratic values. In this paper we use Joppke's binary to show how researching ethnic minority students outside of a liberal democratic framework requires methodologies that enable researchers to see beyond the invisibility that is often attached to ethnic minorities. We show how invisibility (i.e. antidiscrimination) can also be further culturally constructed, confounding even more any broader multicultural project. We canvass four broad areas including the role of legally binding legi...
A relocatable storage magazine apparatus for storing and retrieving explosives and ordnance and for partially containing and attenuating the blast, conflagration and flying debris from an accidental explosion is described comprising: (a) a container having an access hole; (b) a debris trap attached to the container, the debris trap communicating with said container via the access hole, said debris trap having vent holes for venting the pressure of an explosion from said debris trap to the atmosphere; (c) means for covering said access hole; (d) means for suspending explosives and ordnance from the covering means; (e) means for entering the storage magazine to store and retrieve explosives and ordnance; (f) means for retaining said covering means in a position above the access hole wherein said explosives and ordnance are accessible from the entering means.
The Operation Technical Specifications is a document that is attached to the Operation License of a nuclear power station and its are applicable since the first load of fuel begins in the reactor core. This document is normative and with its application it is assured the safe operation of the nuclear power station. For the case of the Laguna Verde Nucleo electric Central this is documented in the Condition No. 5 of the License of Operation. Any modification to the ETOs is subject to the evaluation by part of the regulator organism. This work describes the regulator frame and the evaluation process of the Improved Technical Specifications on the part of the regulator organism. It is also indicated the implementation process of the improved ETOs and the main characteristics and benefits that are obtained of these processes to maintain the safety of the nuclear power stations. (Author)
A biodegradable polylactic acid (PLA)/poly(glycolide-co-lactide) copolymer (PLGA) membrane with polyglycolic acid (PGA) mesh was prepared to aid the effective regeneration of defective periodontal tissues. The microporous membrane used in this study consists of biodegradable polymers, and seems to have a structure to provide appropriate properties for periodontal tissue regeneration. Based on the albumin permeation test, it is known that the biodegradable membrane exhibits the suitable permeability of nutrients. The membrane maintained its physical integrity for 6-8 weeks, which could be sufficient to retain space in the periodontal pocket. Cell attachment and cytotoxicity tests were performed with respect to the evaluation of biocompatibility of the membrane. As a result, the membrane did not show any cytotoxicity. The safety and therapeutic efficacies of the biodegradable membranes were confirmed in animal tests.
Photoelectron resonance capture ionization (PERCI) is a soft and sensitive ionization method, based on the attachment of low-energy (<1 eV) photoelectrons to organic analyte molecules. PERCI has been developed in our laboratory for the real-time analysis of organic particles by mass spectrometry, and is employed here to monitor the heterogeneous reaction of ozone with oleic acid. Simplified identification of the reaction products is possible as a result of the soft nature of PERCI, giving predominantly the [M--H](-) ions. The major particle-phase products are identified as: 1-nonanal, nonanoic acid, 9-oxononanoic acid, and azelaic acid, consistent with proposed mechanisms. New insight into this well-studied heterogeneous reaction is gained as additional minor particle-phase products, consistent with the Criegee mechanism, are readily detected. PMID:15468105
Periphyton is typically a heterogeneous assemblage of filamentous and single celled photoautotrophic and heterotrophic micoorganisms suspended in a mucopolysaccharide matrix which they produce. By definition, the assemblage is attached to a substratum such as rock, sediment, or plant in an aquatic environment. Microtechniques with high spatial and temporal resolution are required to define metabolic interactions among the heterotrophic and autotrophic constituents, and between periphyton and its environment. This study used oxygen sensitive microelectrodes with tip diameters of < 30 m to investigate the effects of photosynthesis and respiration on the oxygen dynamics of several diverse periphyton communities both in situ and in laboratory microcosms. A novel flow-through system that utilized TSP radiotracer and that permitted manipulation of the velocity, flushing rate, and oxygen concentration of overlying water was developed to investigate the role of ...
Here, a general approach for the preparation of reduced graphite oxide (rGO)-silver nanocomposite has been investigated. Graphite oxide (GO) sheets are used as the nanoscale substrates for the formation of rGO-silver composite. GO sheets and Ag ions can be reduced at the same time, under a mild condition using l-ascorbic acid (l-AA) as reducing agent. This simple approach should find practical applications in the production of rGO-silver nanocomposite. The SEM analysis indicates that the silver particles are dispersed on graphene sheets. Raman signals of rGO in the composite are increased by the attached silver nanoparticles, displaying surface-enhanced Raman scattering activity. The degree of enhancement can be adjusted by varying the quantity of silver nanoparticles in the composite. In ...
This study was focused on the possibility to inactivate main food pathogens, their spores and biofilms on the surface of packaging material polyolefine by Na-chlorophyllin (Na-Chl)-based photosensitization and to compare efficiency of this treatment with conventional antimicrobials. Data indicate that Bacillus cereus and Listeria monocytogenes were effectively inactivated (7 log) by Na-Chl (7.5x10-7M)-based photosensitization in vitro and on the surface of packaging. Meanwhile to achieve adequate inactivation of thermo-resistant strains, spores or biofilms the higher Na-Chl concentration and longer illumination times had to be used. Comparison of different surface decontamination treatments reveal that photosensitization is much more effective against B. cereus and L. monocytogenes attache...
Lipophilic tertiary amines attached to cylcopentadienyl technetium-99m tricarbonyl (cytectrene) have been prepared with high radiochemical yield and purity. Biodistribution studies in mice showed that [{sup 99m}Tc]-cytectrenes, containing in their structure an N-methylpiperidine, were accumulated in the brain up to 2.8% of injected dose with high brain-to-blood ratios at 15 min p.i. They therefore indicate some potential as brain imaging agents. It has to be pointed out that the N-methylpiperidine ester showed similar biological behaviour as the keto derivatives. This indicates that the conversion to polar metabolite(s) via hydrolysis of the ester group - as described for [{sup 99m}Tc]-ECD -is not essential for brain retention. (Author).
Lipophilic tertiary amines attached to cylcopentadienyl technetium-99m tricarbonyl (cytectrene) have been prepared with high radiochemical yield and purity. Biodistribution studies in mice showed that ["9"9"mTc]-cytectrenes, containing in their structure an N-methylpiperidine, were accumulated in the brain up to 2.8% of injected dose with high brain-to-blood ratios at 15 min p.i. They therefore indicate some potential as brain imaging agents. It has to be pointed out that the N-methylpiperidine ester showed similar biological behaviour as the keto derivatives. This indicates that the conversion to polar metabolite(s) via hydrolysis of the ester group - as described for ["9"9"mTc]-ECD -is not essential for brain retention. (Author).
Nano photonic materials are synthetically manufactured crystals at the nano scale with the target of creating a microstructure with a special electro-magnetic periodicity. Such nano photonic materials have the ability to control light propagation and thus are capable of creating photonic bandgaps in the frequency domain. We propose using nano photonic crystals as sensors to detect microdamage in composite materials. We demonstrate using a simulation model that a nano photonic sensor attached to a composite bar experiences a significant change in its bandgap profile when damage is induced in the composite bar. The model predicts the frequency response of the nano photonic sensor using the transfer matrix method. A damage metric to evaluate the change in the frequency response is developed. Successful developments of nano photonic sensors allow damage identification at scales not attainable using current sensing technologies.
Abstract Aims: To develop a new nano composite of multi walled carbon nanotubes (MWNTs) with enhanced antimicrobial activity. Methods and Results: A novel antimicrobial nanocomposite [MWNT epilson polylysine (MEPs)] was synthesized via covalent attachment of epilson polylysine on MWNTs with hexamethylene diisocyanate (HDI) as the coupling agent. UV visible spectra and Fourier transform infrared spectra (FT IR) investigations indicate that MEPs is stable, with epilson polylysine leaching effectively eliminated. When compared to MWNTs, the new nano composite MEPs exhibits enhanced antimicrobial activities. In 20 mg l 1 suspensions, significant increases of 72 1, 64 5 and 69% against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus can be observed. The deposited film of MEPs...
A miniature x-ray source utilizing a hot filament cathode. The source has a millimeter scale size and is capable of producing broad spectrum x-ray emission over a wide range of x-ray energies. The miniature source consists of a compact vacuum tube assembly containing the hot filament cathode, an anode, a high voltage feedthru for delivering high voltage to the cathode, a getter for maintaining high vacuum, a connector for initial vacuum pump down and crimp-off, and a high voltage connection for attaching a compact high voltage cable to the high voltage feedthru. At least a portion of the vacuum tube wall is fabricated from highly x-ray transparent materials, such as sapphire, diamond, or boron nitride.
A metal spray apparatus is provided with a supersonic nozzle. Molten metal is injected into a gas stream flowing through the nozzle under pressure. By varying the pressure of the injected metal, the droplet can be made in various selected sizes with each selected size having a high degree of size uniformity. A unique one piece graphite heater provides easily controlled uniformity of temperature in the nozzle and an attached tundish which holds the pressurized molten metal. A unique U-shaped gas heater provides extremely hot inlet gas temperatures to the nozzle. A particularly useful application of the spray apparatus is coating of threads of a fastener with a shape memory alloy. This permits a fastener to be easily inserted and removed but provides for a secure locking of the fastener in high temperature environments.
SR proteins are essential splicing factors whose function is controlled by multi-site phosphorylation of a C-terminal domain rich in arginine-serine repeats (RS domain). The protein kinase SRPK1 has been shown to polyphosphorylate the N-terminal portion of the RS domain (RS1) of the SR protein ASF/SF2, a modification that promotes nuclear entry of this splicing factor and engagement in splicing function. Later, dephosphorylation is required for maturation of the spliceosome and other RNA processing steps. While phosphates are attached to RS1 in a sequential manner by SRPK1, little is known about how they are removed. To investigate factors that control dephosphorylation, we monitored region-specific mapping of phosphorylation sites in ASF/SF2 as a function of the protein phosphatase PP1. W...
Our understanding of prenatal behavior has been significantly advanced by techniques for direct observation and manipulation of unanesthetized, behaving rodent fetuses with intact umbilical connections to the mother. These techniques involve brief administration of an inhalant anesthesic, enabling spinal transection of the rat or mouse dam, after which procedures can continue with unanesthetized dams and fetuses. Because anesthetics administered to the mother can cross the placental barrier, it is possible that fetuses are anesthetized to varying degrees. We compared in perinatal rats the effects of prenatal maternal exposure to two inhalant anesthetics: ether and isoflurane. Fewer spontaneous fetal movements and first postpartum nipple attachments were observed following maternal exposure...
Bags of explosive are loaded rapidly into deep wellbores by suspending a rigid positioning tube partway into the wellbore, and loading the bags into the tube, the bags being prevented from dropping through the open bottom end of the tube by a cord attached to the lowermost bag and secured at the upper end of the tube when the tube-suspending cable is in tension by a cordsecuring/releasing means, E.G., a pivotable bar having a hook on one end. When the bag-laden tube is lowered to the bottom of the wellbore, or to a column of bags previously placed therein, the tension on the cable is relaxed and the cord is released, allowing the positioning tube thereafter to be raised to the surface for re-use, leaving the cord and bags in the wellbore. Freedom of the bag-supporting cord to move with respect to the positioning tube when the latter is raised to the surface is assured by threading the cord through plastic tubing mounted to the wall of the positioning tube and ...
This report, which summarizes the result of preliminary conceptual design activities during Phase 1, follows the format of safety analysis report. The purpose of publishing this report is to gather all of the design information developed so far in a systematic way so that KALIMER designers have a common source of the consistent design information necessary for their future design activities. This report will be revised and updated as design changes occur and more detailed design specification is developed during Phase 2. Chapter 1 describes the KALIMER Project. Chapter 2 includes the top level design requirements of KALIMER and general plant description. Chapter 3 summarizes the design of structures, components, equipment and systems. Specific systems and safety analysis results are described in the remaining chapters. Appendix on the HCDA evaluation is attached at the end of this report.
Eu3+ ions are anchored on TiO2 matrix by coupling with 2,2'-bipyridyl 4,4'-dicarboxylic acid. Five different luminescence centers are observed for TiO2|2,2'-bipyridyl 4,4'-dicarboxylic acid|Eu3+ electrodes due to electron transitions between d and f orbitals. Photo-luminescence of TiO2|2,2'-bipyridyl 4,4'-dicarboxylic acid|Eu3+ electrodes is increased by attaching 2-thenoyltrifluoroacetone to Eu3+ ions. Immersion of TiO2|2,2'-bipyridyl 4,4'-dicarboxylic acid|Eu3+|2-thenoyltrifluoroacetone electrodes in propylsulfide is found to be further increased intensities of luminescence bands by a factor of three.
This study was focused on the possibility to inactivate thermosensitive Listeria monocytogenes ATCL3C 7644 and thermoresistant 56 Ly strain by Na-Chlorophyllin (Na-Chl)-based photosensitization in vitro and on the surface of packaging. Comparative analysis of antimicrobial efficiency of photosensitization with conventional surface cleaning was performed. Data indicate that both Listeria strains, after incubation with Na-Chl and following illumination (l=400nm, 20mWcm-2), were inactivated by 7 log in vitro. This treatment cleaned both Listeria strains from packaging surfaces. Comparative analysis indicates that washing with water diminishes pathogens by less than 1 log, 200ppm Na-hypochlorite by 1.7 log, Na-Chl-based photosensitization by 4.5 log. Listeria biofilms were totally removed from...
The following is the optimized pulsed laser deposition (PLD) procedure by which we prepared the final samples that were sent to LLNL. These samples are epitaxial multilayer structures of Si/YSZ/CeO/NSMO, where the abbreviations are explained in the following table. In this heterostructure, YSZ serves as a buffer layer to prevent deleterious chemical reactions, and also serves to de-oxygenate the amorphous SiO{sub 2} layer to generate a crystalline template for epitaxy. CeO and BTO serve as template layers to minimize the effects of thermal and lattice mismatch strains, respectively. More details on the buffer and template layer scheme are included in the manuscript [Yong et al., 2008] attached to this report.
IntroductionMost clinical studies on the outcome of apical surgery concentrate on periapical healing based on radiographic and clinical characteristics (signs and symptoms). This study focuses on long-term changes in periodontal parameters after apical surgery. MethodsPeriodontal parameters (ie, probing depth [PD], level of gingival margin [GM], and calculated clinical attachment level [CAL]) were collected at baseline and at 1 and 5 years after apical surgery. Changes in PD, GM, and CAL were calculated over time and were also evaluated in relation to patient-, tooth-, and treatment-related covariables. ResultsOne hundred eighty-six of 242 initially identified teeth could be evaluated. Significant changes in GM and CAL were observed at facial sites during the first year after surgery (mean...
We report on the fabrication of nanomechanical devices for shuttling of electrons from one electrode to another. Each device consists of a 20 nm diameter gold nanoparticle embedded within the gap between two gold electrodes. In two different kinds of shuttle-junctions the nanoparticle is attached to the electrodes through either (i) a single layer of 1,8-octanedithiol or (ii) a multilayer of 1-octanethiol molecules. The thiol layers play the role of 'damped springs', such that when a sufficient voltage bias is applied to the junction, the nanoparticle is expected to start oscillating and thereby transferring electrons from one electrode to the other. For both kinds of shuttle-junctions we observed an abrupt increase in the transmitted current above a threshold voltage, which can be attributed to a transition from the stationary to the oscillating regime. The threshold voltage was found to be lower for single-layer shuttle-junctions.
A novel method to control the mixed-mode bending (MMB) specimen is presented. By maintaining a constant opening, or Mode 1, displacement rate, stable delamination growth is achieved for all mixed-mode ratios. A constant-opening displacement rate is achieved by attaching a second displacement transducer to the hinges of the specimen. The test machine is then controlled externally by the second displacement transducer. By achieving stable delamination growth and monitoring the opening displacement, an experimental compliance calibration may be derived for the Modes 1 and 2 parts. This new approach to control the test and determine the experimental compliance calibration, overcomes the potential inaccuracies of the previously used beam theory expressions to determine compliance and to separate the modal values of G.
Experiments of highly subcooled nucleate pool boiling of FC-72 with dissolved air were studied both in short-term microgravity condition utilizing the drop tower Beijing and in normal gravity conditions. The bubble behavior and heat transfer of air-dissolved FC-72 on a small scale silicon chip (10 ? 10 ? 0.5?mm3) were obtained at the bulk liquid subcooling of 41?K and nominal pressure of 102?kPa. The boiling heat transfer performance in low heat flux region in microgravity is similar to that in normal gravity condition, while vapor bubbles increase in size but little coalescence occurs among bubbles, and then forms a large bubble remains attached to the heater surface during the whole microgravity period. Thermocapillary convection may be an important mechanism of boiling heat transfer in ...
Heart cells from the clam Ruditapes decussatus were routinely cultured with a high level of reproducibility in sea water based medium. Three cell types attached to the plastic after 2?days and could be maintained in vitro for at least 1?month: epithelial-like cells, round cells and fibroblastic cells. Fibroblastic cells were identified as functional cardiomyocytes due to their spontaneous beating, their ultrastructural characteristics and their reactivity with antibodies against sarcomeric ?-actinin, sarcomeric tropomyosin, myosin and troponin T-C. Patch clamp measurements allowed the identification of ionic currents characteristic of cardiomyocytes: a delayed potassium current (I K?slow) strongly suppressed (95%) by tetraethylammonium (1?mM), a fast inactivating potassium current (I K?fas...
Electron simulated desorption of anions from CFCl_3 and CF_2Cl_2 condensed on an Au substrate is studied in the energy range 0-15 eV. The negative fragments are recorded mass spectro metrically as the function of the incident electron energy. Below 10 eV we observe anion desorption via pronounced resonance profiles which are characteristic for dissociative electron attachment (DA) while the continuous rise of the signal at higher energies accounts for dipolar dissociation (DD) and processes involving secondary electrons from the metallic substrate. For both compounds F"- and Cl"- are the only fragment anions we could observe. (author).
The invention is a mechanism for retaining an electrical transmission line. In one embodiment of the invention it is a system for retaining an electrical transmission line within downhole components. The invention allows a transmission line to be attached to the internal diameter of drilling components that have a substantially uniform drilling diameter. In accordance with one aspect of the invention, the system includes a plurality of downhole components, such as sections of pipe in a drill string, drill collars, heavy weight drill pipe, and jars. The system also includes a coaxial cable running between the first and second end of a drill pipe, the coaxial cable having a conductive tube and a conductive core within it. The invention allows the electrical transmission line to withstand the tension and compression of drill pipe during routine drilling cycles.
Sandia Laboratories, as part of its investigation of the Darrieus Vertical Axis Wind Turbine (VAWT), has been involved recently in an economic assessment of the concept. The class of VAWT's investigated use curved, fixed-pitch blades of constant section rigidly attached to a vertical rotating tower. Qualitatively, the main advantages of the VAWT over more conventional, propeller-type machines are the elimination of yaw controls, the placement of mechanical equipment at ground level, its amenability to simple, low-cost blade fabrication techniques, and aerodynamic stall characteristics which eliminate the need for active pitch control devices. The main disadvantages relative to modern propeller machines are a somewhat lower aerodynamic efficiency (about 10% lower), the limited ability of the rotor to self-start, and generally lower rotor operating RPM's, which leads to higher torque capacity requirements for the drive train.
The class of vertical axis wind turbines (VAWT) investigated use curved, fixed-pitch blades of constant section rigidly attached to a vertical rotating tower. Qualitatively, the main advantages of the VAWT over more conventional, propeller-type machines are the elimination of yaw controls, the placement of mechanical equipment at ground level, its amenability to simple, low-cost blade fabrication techniques, and aerodynamic stall characteristics which eliminate the need for active pitch control devices. The main disadvantages relative to modern propeller machines are a somewhat lower aerodynamic efficiency (about 10 percent lower), the limited ability of the rotor to self-start, and generally lower rotor operating RPM's, which leads to higher torque capacity requirements for the drive train.
Disorder on the string theory landscape may significantly affect dynamics of eternal inflation leading to the possibility for some vacua on the landscape to become dynamically preferable over others. We systematically study effects of a generic disorder on the landscape starting by identifying a sector with built-in disorder -- a set of de Sitter vacua corresponding to compactifications of the Type IIB string theory on Calabi-Yau manifolds with a number of warped Klebanov-Strassler throats attached randomly to the bulk part of the Calabi-Yau. Further, we derive continuum limit of the vacuum dynamics equations on the landscape. Using methods of dynamical renormalization group we determine the late time behavior of the probability distribution for an observer to measure a given value of the cosmological constant. We find the diffusion of the probability distribution to significantly slow down in sectors of the landscape where the number of nearest neighboring vacua ...
This document includes the following topics: Background; Data Collection; Scope/Applicability of the Proposed Regulation; Description of the Industry; Industry Subcategorization; Pollutants of Concern for the Centralized Waste Treatment Industry; Pollutants Selected for Regulation; Wastewater Treatment Technologies; Regulatory Options Considered and Selected for Basis of Regulation; Long-Term Averages, Variability Factors, and Limitations and Standards; Cost of Treatment Technologies; Pollutant Loading and Removal Estimates; Non-Water Quality Impacts; Implementation; Analytical Methods and Baseline Values; List of Definitions; List of Acronyms; Appendix A--Pollutant Groups; Appendix B--Listing of Characerization Data From Non-Hazardous Oils Facilities; Appendix C--Listing of Daily Influent and Effluent Measuements; Appendix D--Facility-Specific Compliance Costs; Appendix E--Attachements to Chapter 10; and Appendix F--Listing of Pollutants of Concern and Cas ...
Photoelectron resonance capture ionization aerosol mass spectrometry (PERCI-AMS) has been applied to the analysis of proxies for marine aerosols with and without ozone; proxies used were mixed oleic acid-amino acid particles. The mechanism of ion formation for serine (104 m/z), glutamic acid (146 m/z), and phenylalanine (164 m/z) was dissociative electron attachment. This corresponds to loss of the hydrogen atom only, allowing for straightforward identification of the free amino acids. No ozonolysis products for the free amino acids were observed, even at high concentrations of ozone (500 ppm for 19 s). The direct detection of a novel gas-phase hydrated anion, [serine + H2O-H]-, is described. These preliminary results suggest that PERCI-AMS may provide an effective, simple and direct onlin...
A decontamination washer for working dresses using liquid and supercritical carbon dioxide were designed and manufactured. The size of reactor for decontamination and solidification is about 16 liter. The system is a closed one with recycling ability of carbon dioxide. The efficiency of recycling of carbon dioxide and that of separation of solutes in carbon dioxide were checked. They met all the design goals. A remote control system of the carbon dioxide flow was set in a control panel. The manufactured decontamination washer was brought to Wolsung nuclear power plants, and installed to check the efficiency of decontamination and the feasibility of usage in nuclear power plants. The elimination of radioactive oil from the contaminated dresses were very high. However, the decontamination factor was lower than the design goal value. It's due to the low removal rate of radioactive particles attached on the dresses.
In eukaryotes, accurate chromosome segregation during mitosis and meiosis is coordinated by kinetochores, which are unique chromosomal sites for microtubule attachment. Centromeres specify the kinetochore formation sites on individual chromosomes, and are epigenetically marked by the assembly of nucleosomes containing the centromere-specific histone H3 variant, CENP-A. Although the underlying mechanism is unclear, centromere inheritance is probably dictated by the architecture of the centromeric nucleosome. Here we report the crystal structure of the human centromeric nucleosome containing CENP-A and its cognate ?-satellite DNA derivative (147 base pairs). In the human CENP-A nucleosome, the DNA is wrapped around the histone octamer, consisting of two each of histones H2A, H2B, H4 and CENP...
In 16 female patients wick colpourethrocystography was performed directly successively with large-size films as well as medium-size films (intensifier fluorography). The area exposure products were measured by a dosemeter closely attached to the diaphragm and separately for radiography and fluorography, resp. Surface doses as well as organ doses were calculated according to Rosenstein. The average radiatin doses of the active bone marrow were 6.03 mGy for examination with large-size films and 1.27 mGy for fluorography; the average gonadal doses were 7.45 mGy and 1.56 mGy, resp. The portion of fluoroscopy in radiation exposure amounted to 14.8% in large-size film examination, but was 74.0% in medium-size examination. Thus the comparative results revealed a significant reduction of the patient's radiation dose by application of intensifier fluorography in colpourethrocystography.
We have colocalized elastin and fibrillin-1 with perlecan in extracellular matrix of tensional and weight-bearing connective tissues. Elastin and fibrillin-1 were identified as prominent components of paraspinal blood vessels, and posterior longitudinal ligament in the human fetal spine and outer annulus fibrosus of the fetal intervertebral disc. We also colocalized perlecan with a synovial elastic basal lamina, where the attached synovial cells were observed to produce perlecan. Elastin, fibrillin-1 and perlecan were co-localized in the intima and media of small blood vessels in the synovium and in human fetal paraspinal blood vessels. Elastic fibers were observed at the insertion point of the anterior cruciate ligament to bone in the ovine stifle joint where they colocalized with perleca...
The moment analysis of pulse responses was applied to a biological activated carbon (BAC) bed to evaluate the microbial activity. Glucose and activated carbon fiber (ACF) were employed in experiments as a model tracer and an activated carbon respectively. No significant difference in biodegradation rates of glucose by microorganisms attached on different solid supports such as activated carbon inactivated carbon and glass fibers was observed. However, higher microbial activity was obtained from microorganisms supported on the ACF in terms of the apparent degradation of total organic including metabolic byproducts by microorganisms, since part of the metabolic byproducts was irreversibly deposited onto the ACF. 11 refs., 6 figs.
The use of dendrimers for preparing chemically sensitive interfaces for detecting volatile organic compounds (VOCs) using surface acoustic wave (SAW) device transducers is described. Specifically, the synthesis of the dendrimers and the means by which they are affixed to SAW devices is discussed, followed by a detailed spectroscopic analysis of the surface-confined dendrimers and a discussion of their interaction with different VOCs. Most of these preliminary experiments focus on dendrimer surface modification using benzoylchloride, which leads to phenyl terminal groups linked to the dendrimer via amide groups. The results of this study lead us to conclude that dendrimers: (1) provide general specificity towards classes of functional groups and are therefore suitable for array-based sensing schemes; (2) are intermediate in structure between monolayers and polymers and exhibit the desirable properties of both; (3) can be straightforwardly attached to the surfaces of ...
This paper describes progress in several projects related to biomass power. These include switchgrass conversion development; switchgrass gasification development; production activities including soil studies, carbon studies, switchgrass production economics, watershed impacts, and prairie lands bio-products; information and education; and geographical information system. Attachments describe switchgrass co-firing test; switchgrass production in Iowa; cooperative agreements with ISU; Rathbun Lake watershed project; newspaper articles and information publications; Secretary of Agriculture Glickman`s visit; integration of technical aspects of switchgrass production in Iowa; and evaluation of an integrated biomass gasification/fuel cell power plant.
Algorithms for the authentication of byte sequences are described. The algorithms are designed to authenticate data in the Storage, Retrieval, Analysis, and Display (SRAD) Test Data Archive of the Radiation Effects and Testing Directorate (9100) at Sandia National Laboratories, and may be used in similar situations where authentication of stored data is required. The algorithms use a well-known error detection method called the Cyclic Redundancy Check (CRC). When a byte sequence is authenticated and stored, CRC bytes are generated and attached to the end of the sequence. When the authenticated data is retrieved, the authentication check consists of processing the entire sequence, including the CRC bytes, and checking for a remainder of zero. The error detection properties of the CRC are extensive and result in a reliable authentication of SRAD data.
Canadian-based Anderson Group Company has developed an innovative round baler for harvesting a large variety of woody biomass. The baler was initially developed in 2005 in collaboration with the University Laval and Agriculture and Agri-Food Canada. The third generation BIOBALER{sup TM} is currently built, engineered and commercialized by Anderson. It can produce up to 40 bales/hr in short rotations woody crops such as willow and hybrid poplar. The unit can harvest brushes up to 125 mm in diameter. A standard tractor can pull the BIOBALER in fallow or abandoned land, under power transmission lines, and between planted trees. The patented BIOBALER includes a mulcher head attachment, a choice of long or short swivel tongue, a fixed chamber and an undercarriage frame.
We have developed a playmate robot system for playing the rock-paper-scissors game with humans. The playmate robot recognizes the hand motions of a human using image processing without attaching any additional units to the human. The playmate robot system consists of three parts: a game management part, a hand motion recognition part, and a robot hand control part. The system functions as follows. (1) Before the game is played, the game management part decides on the motion of the robot hand from amongst rock, paper, and scissors. After the game is played, the robot develops a reaction using speech and facial expressions depending on the result of the game. (2) The hand motion recognition part recognizes the hand motion of the human. It does not use any additional units on the human?s body...
The flexible, insulated, single strand cables are electrically connected with a cylindrical polar tip (PN) by means of cylindrical and conical shafts for the polar tips, which enter the faces of the divided, multiwire strand, clamped by tension half couplings. The flat ends of the polar tips being joined are positioned in two concentric mandrel bushings, an internal fixed one and an external, axially movable bushing (PV). The internal bushing is rigidly attached to the end of the left polar tip and equipped with three or four rounded, radial openings, whose diameter is determined by the external diameter of the locking device hinges (ShF) of the connecting couplings. The right polar tip is equipped with an annular channel of trapezoidal section into which the locking device hinges enter. The external movable bushing on the right side has a conical turning and on the left, a cylindrical into which the cylindrical spring which holds the movable bushing in the extreme ...
In 2008 the German National Analysis Facility (NAF) at DESY was established. It is attached to and builds on top of DESY Grid infrastructure. The facility is designed to provide the best possible analysis infrastructure for high energy particle physics of the ATLAS, CMS, LHCb and ILC experiments. The Grid and local infrastructure of the NAF is reviewed with a focus on the ATLAS part. Both parts include large scale storage and a batch system. Emphasis is put on ATLAS specific customisation and utilisation of the NAF. This refers not only to the NAF components but also to the di erent components of the ATLAS analysis framework. Experience from operating and supporting ATLAS users on the NAF is presented in this paper. The ATLAS usage of the di erent components are shown including some typical use cases of user analysis. Finally, the question is addressed, if the design of the NAF meets the ATLAS expectations for effcient data analysis in the era of LHC data taking.
Technetium-99m was previously shown to form a stable, neutral and lipopholic complex with propylene amine oxime, PnAO. This Tc-99m-PnAO complex was shown to efficiently extracted by normal brain. However, it is not sufficiently retained in the brain to image its cerebral distribution using convertional SPECT (single-photon emission computerized tomography) instrumentation. A number of derivatives of PnAO have been synthesized and their technetium-99m complexes have been biologically evaluated. A number of these have been shown to have high brain uptake without exhibiting the rapid cerebral clearance that was observed with Tc-99m-PnAO. To better understand the chemistry of these potential brain imaging agents, a number of technetium-99 complexes of derivatives of PnAO have been synthesized and characterized. Substituents on the tetradentate amine oxime backbone were varied to probe the effect(s) of these ...
The method of proton magnetic resonance (PMR) has been used to study the mechanism of reaction of complexing of paramagnetic Pr/sup 3 +/ ion with ethylenediaminetetra acetic acid (EDTA). The influence of medium acidity (pH5-12), EDTA/Pr ratio varying from 1 to 50, Pr/sup 3 +/ ion concentration (from 5x10/sup -3/ to 3x10/sup -1/ g-ion/l) and temperature (8-98 deg C) on chemical shifts and broadening of signals of EDTA molecule protons is investigated. Data on ratio of components, coordination and stability of forming complexes are obtained. The existence of two types of complexes with the Pr/EDTA ratio equal to 1:1 and 1:2 has been found. Equimolecular complex (1:1) is stable all over the studied temperature interval in contrast to the complex 1:2 for which at 50 deg C fast extrasphere exchange (Pr EDTA)EDTA * + EDTA/sup 0/ reversible (PrEDTA)EDTA/sup 0/ + EDTA * is observed, while ...
Several dioxomolybdenum(VI) complexes of the schiff bases derived from salicylaldehyde, 2-hydroxy-1-naphthaldehyde, o-hydroxyacetophenone or pyridoxal and o-aminobenzylalcohol, o-aminophenol, o-hydroxybenzylamine, o-hydroxy(methylbenzyl)amine or 3-amino-2-naphthoic acid have been synthesized and characterized by elemental analysis, electrical conductance, molecular weight, IR and electronic spectral and magnetic susceptibility measurements. The schiff bases behave as dibasic, tridentate ligands and coordinate through ONO donor system forming complexes of the type MoO_2L.X (where LH_2=schiff base, X=H_2O or Ch_3OH). The compounds MoO_2L.Ch_3OH react with 2,2'-dipyridyl to form heterochelates of the type MoO_2L.dipyridyl. The complexes are non-electrolytes, monomers, diamagnetic and possess a cis-MoO_2 structure. The complexes exhibit a ligand-to-metal charge-transfer transition around 25000 cm"-"1. The ...
The reaction of the chelating ligands (obtained by the condensation of 2-hydroxy-1-naphthaldehyde with various primary amines) with [RuHCl(CO)(EPh3)2(B)] (where E=P; B=PPh3, py or pip: E=As; B=AsPh3) in benzene afforded new stable ruthenium(II) carbonyl complexes of the general formula [Ru(Cl)(CO)(EPh3)(B)(L)] (L=anion of bidentate Schiff bases). The structure of the new complexes was investigated using elemental analyses, spectral (FT-IR, UV-vis and 1H NMR) and electrochemical studies and is found to be octahedral. All the metal complexes exhibit characteristic MLCT absorption and luminescence bands in the visible region. The luminescence efficiency of the ruthenium(II) complexes was explained based on the ligand environment around the metal ion. These complexes catalyze oxidation of prim...
Antitumor platinum(II) complexes derived from N-alkyl-propanediamine differing in the length of their carbon chain (C8, C10, C12 and C14) were incorporated in liposomes and the cytotoxic activity of these formulations was evaluated against tumor (A{sub 549}, MDA-MB-231, B16-F1 and B16-F10) and non-tumor (BHK-21 and CHO) cell lines. Stable and monodisperse liposome suspensions incorporating the platinum complexes were obtained from the lipid composition consisting of distearoyl-sn-glycero-3-phosphocholine, cholesterol and 1,2-distearoyl-sn-glycero- 3-phosphoethanolamine-N-(methoxy(polyethylene glycol)-2000) at 5:3:0.3 molar ratio. The entrapment efficiency (EE%) of the platinum complexes in liposomes increased with the carbon chain length. EE% was higher than 80% in C12- and C14-derivatives. The effect of liposome encapsulation on the cytotoxic activity of the complexes was found to depend on the carbon ...
Extraction of copper-, nickel-, zinc- and cadmium complexes with 4-(2 pyridilazo)-resorcin (PAR) is studied in the presence of 2-aminopyridine (Am). Maximum optical densities of the extracts are attained at pH=7.5-8.0; 6.0-7.0; 6.5-7.0 and 7.0-8.0, respectively. The ratio of components in the complexes extractable by chloroform was defined by the method of isomolar series and equilibrium shift. It is established that nickel and copper are extracted to the organic phase as the NiAm(PAR)_2 and CuAmPAR complexes, and, in the case of zinc and cadmium, complexes of different composition are extracted, for example Zn(Am)_2PAR and ZnAm(PAR)_2. The light absorption spectra are studied and molar extinction coefficients of complex extracts are determined at lambdasub(max). It is shown that the general low of light absorption is observed within a sufficiently wide range of concentrations for ...
Let $M$ be a complex manifold of complex dimension $n+k$. We say that the functions $u_1,...s,u_k$ and the vector fields $\\xi_1,...,\\xi_k$ on $M$ form a \\emph{complex gradient system} if $\\xi_1,...,\\xi_k,J\\xi_1,...,J\\xi_k$ are linearly independent at each point $p\\in M$ and generate an integrable distribution of $TM$ of dimension $2k$ and $du_\\alpha(\\xi_\\beta)=0$, $\\d^c\\u_\\alpha(\\xi_\\beta)=\\delta_{\\alpha\\beta}$ for $\\alpha,\\beta=1,...,k$. We prove a Cauchy theorem for such complex gradient systems with initial data along a $\\CR-$submanifold of type $(\\CRdim,\\CRcodim)$. We also give a complete local characterization for the complex gradient systems which are \\emph{holomorphic} and \\emph{abelian}, which means that the vector fields $\\xi_\\alpha^c=\\xi_\\alpha-J\\xi_\\beta$, $\\alpha=1,...,k$ are holomorphic and satisfy $[\\xi_alpha^c,\\bar{\\xi_\\beta^c}]=0$ ...
Chelating tendencies of several biologically important compounds viz. glycocyamine (GCN: N-amidino-aminoethanoic acid) taurine (TRN: 2-aminoethanesulphonic acid) and pyridoxal [PDL: 3-hydroxy-5-(hydroxymethyl)-2-methyl-pyridine-4-carbaldehyde] have been examined by pH-metric titration technique in their binary complex formation with copper(II) and uranyl(VI) ions. The work has further been extended to investigating the ternary complex formation involving 2.2'-bipyridine. 1,10-phenanthroline or nitrilotriacetic acid as a primary and TRN and PDL as secondary ligands. All the experiments were carried out at 25"0C and at an ionic strength of 0.1M (NaCl0_4) in aqueous or 50% (v/v) aqueous-ethanol medium according to the suitability of the experimental conditions. Stabilities of ternary complexes as compared to those of the corresponding binary complexes of the secondary ligands have also been discussed. ...
We studied a novel universal spectrochemical series of six-coordinated octahedral 3d transition metal complexes, which can be used for any combination of central metal atom and ligand molecules. A two dimensional spectrochemical series could be used to estimate the ligand field splitting energy of not only known compounds but also the unknown compounds. Therefore, it should be possible to control the physical properties, such as the electronic and magnetic properties and the optical phenomena of octahedral transition metal complexes by modifying the ligand field splitting. PMID:19378561
Advanced techniques for focused-ion-beam (FIB) device modification have been developed for complex, multistep modifications to circuitry on planar chip technology. Applying gas-assisted etching (GAE) techniques for high-aspect-ratio milling and the selective milling of both conductive and insulating films enhances process latitude. Localized ion-beam-induced deposition of an insulating film provides reconstructive capability in previously modified areas. The application of both techniques for complex device modification on VSLI devices fabricated with CMOS process technology is reviewed. (UK).
A few metal complexes of isatin-isonicotinoylhydrazone with Ni(II), Cr(III), Co(II), Cu(II), Zn(II) and Cd(II) have been prepared and characterized on the basis of elemental analyses, infrared and electronic spectra as well as "1H NMR spectra, conductivity and magnetic measurements. In view of the results obtained, it has been found that two molecules of isatin-isonicotinoylhydrazone are chelated to the central metal ion as bis-uninegative ONO tridentate ligand forming non-electrolytic octahedral metal complexes. (author)
Of the radionuclides with physical properties most suited for use with monoclonal antibody for tumor imaging or therapy, few are more available or desirable than Pb-203, 212 and Bi-212. Yet no clinical studies have as yet been possible solely due to the lability in vivo of known complexes. We now report that bismuth complexes of the ligands p-SCN-Bz-DOTA and p-SCN-Bz-trans-cyclohexylDTPA are effective at protecting Bi-206 from release when linked to immunoproteins. Practicable, efficient ligand syntheses will be reported. Initial studies reveal that antibody is labeled efficiently with radiolead DOTA complexes. Preliminary studies indicate stability in vivo.
The Conawapa-Winnipeg Power Transmission Complex includes five interrelated transmission and conversion facilities. This booklet describes work done on the upgrade of the southern receiver system, one component of the complex. The southern receiver system is composed of a network of high voltage transmission lines and station facilities. The booklet includes a description of the upgrade, the project setting, short and long-term effects and impact management, and the next steps to be taken in the process, including the regulatory process and public consultation.
In order to increase the sensitivity of photometric determination of tungsten and to find forms with high molar extinction coefficients, mixed-ligand complexes of tungsten with antipyrine and trihydroxyfluorone have been studied. The molar extinction coefficients have been determined for chloride associates of mixed-ligand complexes containing different trioxyfluorones: phenylfluorone, salicylflourone, p-bromphenylfluorone, anthrafluorone, dioxyfluorescein, and dioxyfluoroscein ethylate (DOFE). An associate formed by DOFE has the maximum molar extinction coefficient. It has been used for photometric determination of microgram amounts of tungsten impurity in vanadyl sulphate.
Central nervous system (CNS) development, homeostasis, stress responses, and plasticity are all mediated by epigenetic mechanisms that modulate gene expression and promote selective deployment of functional gene networks in response to complex profiles of interoceptive and environmental signals. Thus, not surprisingly, disruptions of these epigenetic processes are implicated in the pathogenesis of a spectrum of neurological and psychiatric diseases. Epigenetic mechanisms involve chromatin remodeling by relatively generic complexes that catalyze DNA methylation and various types of histone modifications. There is increasing evidence that these complexes are directed to their sites of action by long non-protein-coding RNAs (lncRNAs), of which there are tens if not hundreds of thousands speci...
Several new complexes of isomeric schiff bases derived from salicylaldehyde and o-hydroxybenzylamine/o-aminobenzyl-alcohol with Pr(III), Nd(III), Sm(III), Gd(III), Tb(III), and Dy(III) have been synthesized and characterized by elemental analysis, molar conductance, IR, electronic spectra and magnetic susceptibility measurements. The schiff bases behave as monobasic tridentate ONO donor and dibasic tridentate ONO donor ligands and form complexes of the type Ln(LH)L. (author). 12 refs.
This Addendum to the Facility Safety Plan (FSP) 360 Complex describes the safety requirements for the safe conduct of all biohazardous research operations in all buildings within the 360 complex program areas. These requirements include all the responsibilities and authorities of building personnel, operational hazards, and environmental concerns and their controls. In addition, this Addendum prescribes facility-specific training requirements and emergency controls, as well as maintenance and quality assurance requirements for ES&H-related building systems.
The mechanistic aspects of electrochemical reductions of U"V"IO_2(acac)_2dmso(acac=acetylacetonate, dmso=dimethyl sulfoxide) complex with bidentate ligand(acac) in DMSO were investigated by using cyclic voltammetry, normal pulse voltammetry, and spectrophotometer equipped with an optical transparent thin layer electrode cell. It is concluded that the uranyl complexes with bidentate ligands at the equatorial plane form stable U(V) complexes by the electrochemical reduction and that their molar extinction coefficients in the visible region are very small. (J.P.N.).
This paper is concerned with the determination of a unique scaling parameter in complex scaling analysis and with accurate calculation of dynamics resonances. In the preceding paper we have presented a theoretical analysis and provided a formalism for dynamical resonance calculations. In this paper we present accurate numerical results for two non-trivial dynamical processes, namely, models of diatomic molecular predissociation and of barrier potential scattering for resonances. The results presented in this paper confirm our theoretical analysis, remove a theoretical ambiguity on determination of the complex scaling parameter, and provide an improved understanding for dynamical resonance calculations in rigged Hilbert space.
This paper studies the sorption of chlorine complexes of ruthenium (IV) on the graft copolymer of a polyacrylonitrile fiber with poly-2-methyl-5-vinylpyridine (PAN-MVP). The composition of the fiber is illustrated. It is shown that sorption of chlorine complexes of ruthenium (IV) from acid solutions by a pyridine fiber sorbent takes place according to an anion-exchange mechanism and is due to the formation of compounds of the diamine type (Ru(RPy)/sub 2/Cl/sub 4/).
The US Department of Energy is conducting cleanup operations at the Weldon Spring site, St. Charles, Missouri, that will include development of a 77-ha (191-acre) soil borrow area. Eight wetlands, including riverine and palustrine emergent wetland types and totaling 0.9 ha (2.2 acres), will be eliminated during excavation of the borrow area. A 23-ha (57-acre) wetland/shorebird complex will be created at the Busch Conservation Area. The complex will include 2 ha (5 acres) of palustrine emergent wetland as mitigation for wetland losses in the borrow area.
Main results are summarised for a project carried out with the aim of increasing the knowledge of relations between handling characeristics and properties such as moisture content, particle size and shape etc. Handling characteristics that were studied: angle of repose, friction between fuel and different surfaces, the fuel`s tendency to bridge across openings, and its freezing characteristics. Some forty solid biomass fuels were studied, mainly wood fuels, with particle sized from 1 to 200 mm. New methods were developed for measurement of bridging across openings and freezing characeristics. The angle of repose varied between 25 and 55 deg. The particle shape had a significant influence, a high ratio of length/thickness gave a high angle of repose. When the fuel moisture content was increased the angle of repose first increased, then decreased, and finally increased again. The particle size had no influence. The friction depended more on the surface than on the fuel properties. ...
The DOE-Idaho Operations Office (DOE-ID) has prepared an environmental assessment (EA) on the replacement of the Idaho National Engineering Laboratory Health Physics Instrumentation Laboratory at the Idaho National Engineering Laboratory (INEL). The purpose of this project is to replace the existing Health Physics Instrumentation Laboratory (HPIL) with a new facility to provide a safe environment for maintaining and calibrating radiation detection instruments used at the Idaho National Engineering Laboratory. The existing HPIL facility provides portable health physics monitoring instrumentation and direct reading dosimetry procurement, maintenance and calibration of radiation detection instruments, and research and development support-services to the INEL and others. However, the existing facility was not originally designed for laboratory activities and does not provide an adequate, safe environment for calibration activities. The EA examined the potential environmental impacts of the ...
Microorganisms associated with fractured basalt core were compared to those suspended in groundwater pumped from the same well in the eastern Snake River Plain Aquifer (Idaho, USA). Two wells influenced to different degrees by a mixed-waste plume in the fractured basalt aquifer were examined. In one well, an array of dialysis cells filled with either deionized water or crushed basalt was equilibrated to compare the microorganisms collected in this fashion with those from core and groundwater samples collected in a traditional manner from the same well. Analyses were performed to characterize these samples and to provide a basis for comparison. These included total cell counts by microscopy; total biomass by phospholipid fatty acid analysis; enumerations of viable aerobic heterotrophs, groups of putative aerobic co-metabolic TCE-degraders and aerobic H2-oxidizing bacteria; mineralization of 14C- labeled acetate; and enrichments for dissimilatory iron-reducing bacteria. The 16S rDNA ...
The Richland Operations Office (RL) and Office of River Protection (ORP) are pleased to issue the attached Pollution Prevention Progress Report. We have just met the most aggressive waste reduction and A recycling goals to date and are publishing this report to recognize A the site's progress, and to ensure it will sustain success beyond 1 Fiscal Year 2000. This report was designed to inform the been made by RL and ORP in Waste Minimization (WMin) and Pollution Prevention (P2). RL, ORP and their contractors are committed to protecting the environment, and we reiterate pollution prevention should continue to be at the forefront of the environmental cleanup and research efforts. As you read the attached report, we believe you will see a clear demonstration of RL and ORP's outstanding performance as it has been responsible and accountable to the nation, its employees, and the community in which we live and work. commitment that ...
ObjectivesThe objective of this meeting will be to interface the two ends of the particulate flow spectrum - those working to understand the fundamentals of granular flows and those attempting to control particulate flows in an industrial setting - to develop solutions to the complex problems presented by dense granular flows. We will aim~%~~%~to provide a forum for the interface between practical users of particulate technology and the developers of theories for understanding granular flow;~%~to present [continued...]DescriptionIn practical situations such as those met in industry where segregation and mixing are important, understanding particulate flows is complex due to the presence of polydispersity, anisotropy and complex grain morphology. In attempting to model such systems, many of these features are generally ignored, except perhaps through empirical parameter fitting. Developing a theory to ...
The formation, migration and agglomeration in silicon of fluorine-vacancy complexes have been monitored by single-detector Doppler broadening spectroscopy. After electronics engineers found that fluorine ion implantation effectively eliminated the transient-enhanced diffusion of dopants in the creation of ultra-shallow junctions, a vital step in the further miniaturization of device structures, positron beams have played a pivotal role in providing an insight into the mechanisms underlying this phenomenon, being able to detect FV complexes in implanted and annealed samples. Secondary Ion Mass Spectrometry has provided complementary information on fluorine concentrations so that the nature of the F{sub m}V{sub n} complexes can be further assessed. New results on Si and SiGe structures are presented.
In multi-organisational contexts, scenario building has been used to engage stakeholders in a critical discussion on issues of mutual importance, and to gain their support with regards to possible future responses. A review of existing literature suggests that much has been written regarding the process of scenario development and the benefits of the process, but the detailed analysis of scenario building outcomes, which encompass a large number of issues and their complex interconnections, has not been made explicit for studying and enhancing understanding of a complex societal problem. This paper presents a systematic method for analysing such complex outcomes in order to facilitate reflective thinking on important issues within the wider context for policy development. The method was em...
BackgroundFeature selection is an important pre-processing task in the analysis of complex data. Selecting an appropriate subset of features can improve classification or clustering...Full Text Available
BackgroundCharacterization of the innate immune repertoire of extant cnidarians is of both fundamental and applied interest - it not only provides insights into the basic immunological...Full Text Available
The analysis of complex fluids such as crude oils, fuels, vegetable oils and mixed waste streams poses significant challenges arising primarily from the multiplicity of components, the different properties of the components (polarity, polarizability, etc.) and matrix properties. We have recently introduced an analytical strategy that simplifies many of these analyses, and provides the added potential of linking compositional information with physical property information. This aspect can be used to facilitate equation of state development for the complex fluids. In addition to chemical characterization, the approach provides the ability to calculate thermodynamic properties for such complex heterogeneous streams. The technique is based on the advanced distillation curve (ADC) metrology, wh...
Humans, like other animals, are exposed to a continuous stream of signals, which are dynamic, multimodal, extended, and time varying in nature. This complex input space must be transduced and sampled...Full Text Available
Despite a complex cascade of cellular events to reconstruct the damaged extracellular matrix, ligament healing results in a mechanically inferior scarred ligament. During normal healing, granulation...Full Text Available
In response to stress, cells start transcriptional and transcription-independent programs that can lead to adaptation or death. Here, we show that multiple inducers of autophagy, including nutrient...Full Text Available
Some acylhydrazine derived ONO donor Schiff bases and their Co(II) and Ni(II) complexes have been prepared having the same metal ion (cation) but different anions. These synthesized metal(II) complexes have been characterized on the basis of their elemental analyses, magnetic moment, molar conductance, and IR and electronic spectral data. All of the Schiff base ligands function as tridentates and the deprotonated enolic form is preferred for coordination. In order to evaluate the effect of anions on the bactericidal activity, these synthesized complexes, in comparison to the uncomplexed Schiff bases have been screened against bacterial species., Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa and the results are reported. PMID:18475936
One approach in the design of neutral oxotechnetium complexes is based on the simultaneous substitution of a tridentate dianionic ligand and a monodentate monoanionic coligand on a [Tc(V)O]"+"3 precursor. Following this ''mixed ligand'' concept, a novel "9"9"mTc complex with N,N-bis(2-mercaptoethyl)-N'N'-diethylethylenediamine as ligand and 1-octanethiol as coligand is prepared and evaluated as potential brain radiopharmaceutical. Preparation of the complex at tracer level was accomplished by using "9"9"mTc-glucoheptonate as precursor. The substitution was optimized and a coligand/ligand ratio of 5 was selected. Under this conditions the labeling yield was over 80% and a major product (with radiochemical purity > 80%) was isolated by HPLC methods and used for biological evaluation. Chemical characterization at carrier level was developed using the corresponding rhenium complex as structural model. ...
The dimercaptosuccinic acid metronidazole ester (DMSAMe) was synthesized and radiolabeled with 99mTc to form the 99mTc-DMSAMe complex in high yield. The radiochemical purity of the 99mTc-DMSAMe complex was over 90%, as measured by TLC and by HPLC, without any notable decomposition at room temperature over a period of 6?h. Its partition coefficient indicated that it was a lipophilic complex. The tumor cell experiment and the biodistribution in mice bearing S 180 tumor showed that the 99mTc-DMSAMe complex had a certain hypoxic selectivity and accumulated in the tumor with high uptake and good retention. The tumor/blood and tumor/muscle ratios increased with time, suggesting it would be a possible tumor hypoxia imaging agent.
Interaction of W(6) with sulphonaphtholazoresorcinol (SNAR) in aqueous solution has been studied. Tungsten is determined in the form of sulphonaphtholazoresorcinate by extraction with higher alcohols. The optimum conditions for the formation of a complex of W with SNAR in aqueous solution are as follows: a 10-fold excess of SNAR, concentration of HCl 1-1.5N, ethanol content 5-10 vol.%, time of formation of the complex 30 min. A component ratio for the complex has been established in the case of aqueous solution and extract; molar extinction coefficients are 0.9x10"4 and 1.7x10"4, respectively. The formation constant for the complex being extracted is 2.2x10"2"3. A method has been developed for determination of microgram quantities of W in a vanadium specimen.
Prokaryotic genomes can be annotated based on their structural, operational, and functional properties. These annotations provide the pivotal scaffold for understanding cellular functions on a genome-scale,...Full Text Available
This review focusses on spin crossover complexes with octahedral metal ions which are bound to a tetraazamacrocyclic ligand and additionally either to two monodentate ligands or to one bidentate ligand. Macrocyclic ligands with a sufficiently large ring size prefer to coordinate to metal ions in an equatorial fashion yielding trans-octahedral coordination environments. In contrast, twelve-membered tetraazamacrocycles with high steric rigidity, such as 2,11-diaza[3.3](2,6)pyridinophanes or 2,11-dithia[3.3](2,6)pyridinophane, are prone to form cis-octahedral complexes. While the electronic and the steric properties of the coordinated tetraazamacrocycle in trans-octahedral complexes are very likely responsible for the paucity of observed spin transitions, the cis-octahedral coordination mode ...
Bisaminoethanethiol (BAT) ligands with various gem-dimethyl and amide groups were prepared, and the corresponding neutral Tc-99m complexes were prepared and evaluated for their relative stabilities by ligand-exchange reactions. It was demonstrated that technetium complexes containing gem-dimethyl substituents have higher lipophilicities, whereas those with an amide group possess greater stability, which enhances ligand-exchange reaction. The most interesting observation was that the brain uptake in rats is not determined only by lipophilicity. Apparently, Tc-99m complexes with an amide functional group display lower brain uptakes in rats compared to those without an amide group. The brain uptake was strongly influenced by substituents on the BAT ligand. These factors are critically important and should be taken into consideration when designing Tc-99m-labeled agents for CNS receptor imaging.
A rapid and highly reproducible chromatographic technique has been developed for analysis and purification of complex mixtures of oligoribonucleotides. The method utilizes a column of microparticulate...Full Text Available
ConspectusSelf-assembly allows for the preparation of highly complex molecular and supramolecular systems from relatively simple starting materials. Typically, self-assembled...Full Text Available
This paper first discusses the challenge offered by natural and anthropogenic systems in all of their complexity and then indicates some areas of research in which specific scientific and technological needs are identifiable.
RFID technology is gaining adoption on an increasing scale for tracking and monitoring purposes. Wide deployments of RFID devices will soon generate an unprecedented volume of data. Emerging applications require the RFID data to be filtered and correlated for complex pattern detection and transformed to events that provide meaningful, actionable information to end applications. In this work, we design and develop SASE, a com-plex event processing system that performs such data-information transformation over real-time streams. We design a complex event language for specifying application logic for such transformation, devise new query processing techniques to effi-ciently implement the language, and develop a comprehensive system that collects, cleans, and processes RFID data for deliv-ery of relevant, timely information as well as storing necessary data for future querying. We demonstrate an initial prototype of SASE ...
... stenosis. It looks from the transesophageal and the 3-D echo that most of the problem is really ... posterior leaflet, which you can see on the 3-D echo image is a major source. The anterior ...
Biopharmaceutical R&D complexes are major emission sources of volatile organic compounds (VOCs), which may pose potential health risks for staff on site and residents nearby. In this paper health risk assessments were performed for the VOCs in the ambient air of a typical biopharmaceutical R&D complex in China. Results showed halogenated and alkyl compounds were dominant components among 24 major VOCs from 9 selected sampling sites, inside or around the complex. The principal component analysis (PCA) indicated VOCs were generated predominantly from the biopharmaceutical research activities (factor 1 (F1), 71.6%) and traffic vehicles (factor 2 (F2), 15.4%), which were confirmed by contour maps of five selected VOCs (benzene, toluene, chlorobenzene, methylene chloride and n-hexane) simulated...
Partial words are sequences over a finite alphabet that may contain wildcard symbols, called holes, which match or are compatible with all letters; partial words without holes are said to be full words (or simply words). Given an infinite partial word w, the number of distinct full words over the alphabet that are compatible with factors of w of length n, called subwords of w, refers to a measure of complexity of infinite partial words so-called subword complexity. This measure is of particular interest because we can construct partial words with subword complexities not achievable by full words. In this paper, we consider the notion of recurrence over infinite partial words, that is, we study whether all of the finite subwords of a given infinite partial word appear infinitely often, and we establish connections between subword complexity and recurrence in this more general framework.
The recent acceleration of effort to elucidate and explore the coordination chemistry of technetium has been prompted mainly by the need for a new generation of radiotracers in nuclear medicine, preferentially for tomograhic studies. Current approaches and their limitations in designing "9"9"mTc complexes capable of penetrating cell membranes of the target organs, and remaining there sufficiently long, are reviewed. With the predominance of Tc(V) oxo compounds, especially for brain imaging agents, new N4 and N2S2 coordinate complexes have been developed by shifting from bidentate to tetradentate ligands with a variable side chain or other adjustable reactivity. The search for myocardial imaging agents has focused on a variety of mixed ligand complexes of Tc(III) and most promising [Tc(CNR)_6]"+ complexes of Tc(I). 64 refs. (author).
... Those functions are fundamental routines to build a power model for more complex circuits or functional blocks. ... 21 of 54 6. Memory Power Model ...
Age-associated changes within an individual are inherently complex and occur at multiple levels of organismal function. The overall decline in function of various tissues is known to play a...Full Text Available
This paper studies the analytical application of europium (III)-morin complex which is formed in alkaline medium and has an intense color. The extent of europium extraction was determined by adding to the extract a morin solution in isoamyl alcohol in a 50-100-fold excess with respect to europium. The dependence of the optical density of the extracts on the ph in the system europium (III)-morin-water-organic solvent for different excesses of the reagent is shown: this indicates formation of two extractable complexes, one being dominant in the pH range 4-7, the other at pH greater than or equal to 8.5. The extraction of the europium (III)-morin complex from alkaline solution is used for direct extraction-photometric determination of europium(III) in compounds of elements having amphoteric properties or forming amines (Zns, Mo0/sub 3/).
Although many studies have examined the performance of animals in detecting a frequency change in a sequence of tones, few have measured animals' discrimination of the fundamental frequency...Full Text Available
The polyene antibiotic Amphotericin B (AMB) is one of the first therapeutic agents to be marketed commercially as nanosized formulations in which the drug is associated with lipids as liposomes or complexes....Full Text Available
Synergism has been observed during inhibiting initiated oxidation of styrene or tetralin by organic phosphites in the presence of complex compounds of some transition metals. The results are given of non-additive intensification of antioxidative activity of triphenylphosphite (TPP) and tri-(4-methyl-6-tert.-- butyl)-phenyl-phosphite (TMBP) in the process of initiated oxidation of styrene or tetralin with addition of acetylacetonates of cobalt and vanadyl. During styrene oxidation, inhibition of the reaction with chelate complex of vanadyl is weakened considerably when phosphite is added into the reaction system. During tetralin oxidation, postcatalytic (or branched) oxidation is observed only for large concentration of vanadyl complex. Addition of TPP to above complex sharply increases the induction period. When the induction period is completed, oxidation of tetralin follows the mechanism of usual, ...
impflrtant to the understanding of complex vortical flows. ... tions like the slender wing, flow separations are controlled in the s,. ...... 10, AGARD LS-121, Dec. ...
Formation of the complex of the univalent astatine cation with nitrilotriacetic acid (AtL)[sup 2-] and its stability constant (lgK[sub 1]=8.97(4), 25degC, [mu]=0.1) have been found experimentally for the first time. The complex is stable in perchlorate solutions in presence of 5 . 10[sup -3] mol . l[sup -1] of the oxidizer Na[sub 2]S[sub 2]O[sub 8] in the interval 4[<=]pH[<=]8.5. The complex is supposed to be destroyed in weak alkaline solutions by reduction of astatine to astatide. The deprotonation constant of hypoastatic acid pK[sub dp]=5.23(9) was found to be lower than determined previously. The investigation was carried out by the method of ion electrophoresis in free electrolyte solutions. (orig.).
Formation of the complex of the univalent astatine cation with nitrilotriacetic acid (AtL)"2"- and its stability constant (lgK_1=8.97(4), 25degC, #mu#=0.1) have been found experimentally for the first time. The complex is stable in perchlorate solutions in presence of 5 . 10"-"3 mol . l"-"1 of the oxidizer Na_2S_2O_8 in the interval 4#<=#pH#<=#8.5. The complex is supposed to be destroyed in weak alkaline solutions by reduction of astatine to astatide. The deprotonation constant of hypoastatic acid pK_d_p=5.23(9) was found to be lower than determined previously. The investigation was carried out by the method of ion electrophoresis in free electrolyte solutions. (orig.).
Negative frequency has a physical meaning, the complete description of a frequency signal is a rotating complex signal, in complete description, positive frequency signal exp(iwt) and negative frequency signal exp(-iwt) is two distinguishable and independent frequency signals. Because the real-carrier modulation and demodulation do not distinguish positive and negative frequency, so half of the spectrum resources and signal energy are wasted. The complex-carrier modulation uses the distinguishable positive frequency signal exp(iwt) and negative frequency signal exp(-iwt) as the carrier signals, they can carry different information, so the spectrum resources is full used, the complex-carrier demodulation does not lose signal energy, so the spectrum efficiency is improved.
The EXAFS spectra of the platinum(III) complexes Pt/sub 4/(OAc)/sub 10/(OH)/sub 2/ (I) and Pt/sub 4/ (OAc)/sub 4/(OH)/sub 8/(H/sub 2/O)/sub 2/ (II) have been investigated. It has been found by a curve-fitting method and with the aid of Fourier transformations that the shortest Pt-Pt distances are 2.61 A in complex I and 2.36 and 2.6 A in II. The values of the bond lengths obtained are consistent with the molecular structures proposed for complexes I and II, which contain skeletons of four platinum atoms in the form of a square or a rectangle, as well as with the known literature data on the lengths of Pt-Pt bonds in Pt(III) complexes.
As a new composition of matter, alkali metal or ammonium or tetraalkylammonium diazidoperfluorophthalocyanatoferrate. Other embodiments of the invention comprise compositions wherein the metal of the coordination complex is cobalt, manganese and chromium.
The basic biology of the menstrual cycle is a complex, coordinated sequence of events involving the hypothalamus, anterior pituitary, ovary, and endometrium. The menstrual cycle with all its...Full Text Available
Models can be useful at many different levels when considering complex issues such as biological control of mosquitoes. At an early stage, exploratory models are valuable in exploring the characteristics...Full Text Available
There is considerable interest in the use of silicon devices as qubits for quantum computing. The existence of nuclear spin in a silicon isotope and the complex band structure of silicon are unfavourable for this application of silicon devices. (viewpoint)
A study was made of the kinetics of L-(/sup 3/H)quinuclidinyl benzilate binding with membrane-bound muscarine cholinoreceptors from the rat brain. Determination was made of the rate constants of this process, and constants as a function of ligand concentration was investigated, indicating that there is a complex mechanism of interaction of antagonists with muscarine receptor. With up to 3.5 nM concentrations of L-(/sup 3/H)quinuclidinyl benzilate, the binding reaction occurs in two stages: rapid equilibrated binding is followed by a slow process of conformational isomerization of the receptor-ligand complex. At higher ligand concentrations, there is additional drastic increase in constant of rate of ligand binding a new plateau is reached. Such dependence of rate constant on ligand concentration is indicative of the cooperative nature of interaction between antagonists and muscarine receptors. This is possible if there are in the receptor ...
... Advances in Complex Systems ( ACS) 413 (413) 2001-2011 Springer Advances in Data Analysis and Classification 59 (59) 2008-2011 Advances in Management Advances In Management ...
Much progress has been made in understanding the complex pharmacokinetics of trichloroethylene (TCE). Qualitatively, it is clear that TCE is metabolized to multiple metabolites either locally or into...Full Text Available
Luminescent transition metal complexes are enjoying a growing interest because of their ubiquitous applications in, e.g., the fields of material science, sensors and (biomedical) diagnostics, and iridium(III) and ruthenium(II) complexes are among the best studied. Due to their long-living excited states, these complexes can have a strong interaction with dioxygen, resulting in luminescence quenching. This oxygen quenching might be regarded as an unwanted effect in luminescence imaging, but, on the other hand, it can be exploited for diagnostic and therapeutic applications as well. After a theoretical introduction concerning the dioxygen quenching mechanism and the parameters involved, in the second part of this review we focus on the possibility of tailoring this quenching by modifying sel...
... a given ternary molten salt system under conditions which are greatly " different than the normal method of potentiometric titration, that is, high ...
Contractile vacuole complexes are critical components of cell volume regulation and have been shown to have other functional roles in several free-living protists....Full Text Available
... 1768 1475 360 to 3400 ... The TSC provided an independent assessment of SA based on ... Complexity of Situation Degree of complication (number of ...
Motivation: DNA sequences can be represented by sequences of four symbols, but it is often useful to convert the symbols into real or complex numbers for further analysis. Several mapping...Full Text Available
This communication reports the formation of complex Langmuir monolayer at the air-water interface by charge transfer types of interaction with the water soluble N-cetyl Formula Not Shown -trimethyl ammonium bromide (CTAB) molecules doped with rosebengal (RB), with the stearic acid (SA) molecules of a preformed SA Langmuir monolayer. The reaction kinetics of the formation of RB-CTAB-SA complex monolayer was monitored by observing the increase in surface pressure with time while the barrier was kept fixed. Completion of interaction kinetics was confirmed by FTIR study. This complex Langmuir films at the air-water interface was transferred onto solid substrates at a desired surface pressure to form multilayered Langmuir-Blodgett films. Spectroscopic characterizations reveal some molecular lev...
... USS Cole, on 9 October 2000, in Aden, Yemen, killing ... and complex interior, it can be attacked by a ... Though there has not been an attack on this ...
and the implications for massive star evolution. In recent years, the complex nature of the circumstellar regions of evolved massive stars has become apparent. ...
Americium extraction in different oxidation states in two-phase aqueous system based on polyethylene glycol is investigated. Conditions for quantitative extraction of americium (3) and americium (5) from ammonium sulfate solutions within pH=3-5 interval in the presence of arsenazo 3 are found. Composition of the produced americium complexes with reagent is determined; americium (3) interacts with arsenazo 3 in ammonium sulfate solutions with the formation of MeR and Me_2R composition complexes. Absorption spectrum characteristics of americium (3) and- (5) complexes with arsenazo 3 in ammonium sulfate solutions and extracts based polyethylene glycol aqueous solutions are given. Molar extinction coefficients of americium complexes with arsenazo (3) in these solutions are determined.
Periodontitis is an infectious process characterized by inflammation affecting the supporting structures of the teeth. Porphyromonas gingivalis is a major oral bacterial species implicated...Full Text Available
The DN-tracking method is used to prove the existence of a closed trajectory in a quadratic system of ordinary differential equations in three dimensions.
Purpose.There is a paucity of neuron replacement studies for retinal ganglion cells. Given the complex phenotype of these neurons, replacement of ganglion cells may be impossible....Full Text Available
New nanofibers containing poly(vinyl pyrrolidone)-iodine complex (PVP-iodine) were obtained by electrospinning in order to prepare materials suitable for wound dressings. Different approaches were used: a one-step method based on electrospinning of PVP-iodine or poly(ethylene oxide)/PVP-iodine solutions and a three-step method based on electrospinning of PVP or poly(ethylene oxide)/PVP mixed solutions followed by photo-mediated crosslinking of the obtained nanofibers and subsequent complexation with iodine. The average diameters of the fibers were in the range 150-470nm depending on the composition and on the applied field strength (AFS) and increased with increasing the amount of PEO in the spinning solutions. Higher AFS resulted in greater fiber diameter and in size distribution broadeni...
With the spread of chloroquine resistant Plasmodium falciparum the control of malaria has become increasingly complex. In recent years, particular concern has arisen over how best to prevent malaria...Full Text Available
The economics of medical computer networks are presented in context with the patient care and administrative goals of medical networks. Design alternatives and network topologies are discussed with...Full Text Available
The present work focuses on investigations of a highly selective ligand for Am(III)/Ln(III) separation: bis-triazinyl-pyridine (BTP). By means of nano-electro-spray mass spectrometry, complex formation of BTP with selected elements of the lanthanide series is investigated. We show that the diluent drastically influences complex speciation. Measurements obtained in the extraction-relevant diluent 1-octanol show the occurrence of Ln(BTP){sub i} (i 1-3) species in different relative abundances, depending on the lanthanide used. Here, the relative abundances of the Ln(BTP){sub 3} complexes correlate with the distribution ratios for extraction to the organic phase of the respective lanthanide. (authors)
The evolution of these new ion-exchange resins hinges upon an understanding of the chemistry of actinide metal complexes as they exist in solution and when interacting with the cationic sites. Molecular modeling of electrostatic interactions between the metal complex and the cationic substrate is used to help visualize uptake mechanisms and, eventually, to predict optimized coordination sites. Thus, these new materials integrate the fields of ion-specific chelation and ion-exchange technology. Synthesized resins contain cationic sites designed to facilitate the uptake of plutonium nitrato complexes from high-nitrate solutions, and they exhibit distribution coefficients that are up to 10 times higher than those observed for commercial resins. Additionally, some new resins show surprisingly large Kd`s for anionic complexes of Am(III) and U(VI).
Abstract Hydrogen bonding interactions between amino acids and nucleic acid bases constitute the most important interactions responsible for the specificity of protein binding. In this study, complexes formed by hydrogen bonding interactions between cysteine and thymine have been studied by density functional theory. The relevant geometries, energies, and IR characteristics of hydrogen bonds (H-bonds) have been systematically investigated. The quantum theory of atoms in molecule and natural bond orbital analysis have also been applied to understand the nature of the hydrogen bonding interactions in complexes. More than 10 kinds of H-bonds including intra- and intermolecular H-bonds have been found in complexes. Most of intermolecular H-bonds involve O (or N) atom as H-acceptor, whereas the...
Systemic lupus erythematosus (SLE) persists as a chronic inflammatory autoimmune disease and is characterized by the production of autoantibodies and immune complexes that affects multiple organs....Full Text Available
Governments are increasingly concerned to compare the quality and effectiveness of healthcare interventions but find this a complex matter. Crude hospital statistics can be dangerously misleading and...Full Text Available
"Machines of all kinds depend on complex software to keep them operating safely. But how reliable is the software - and how can we be sure it is reliable?" (4 pages)
Aging can be defined as a progressive decline in physiological efficiency regulated by an extremely complex multifactorial process. The genetic makeup of an individual appears to dictate this rate...Full Text Available
Summary of recent advancesA family of small molecules called ascarosides act as pheromones to control multiple behaviors in the nematode Caenorhabditis elegans....Full Text Available
The hair follicle develops from the primitive embryonic epidermis as a result of complex epithelial-mesenchymal interactions. The full follicle, consisting of epithelial cylinders under control of a...Full Text Available
Carboxylesterases (CE) are ubiquitous enzymes that hydrolyze numerous ester-containing xenobiotics, including complex molecules, such as the anticancer drugs irinotecan (CPT-11) and capecitabine...Full Text Available
In several respects the dorsal thalamus of Trichosurus presents a level of organizational complexity considerably in advance of that seen in Didelphis. In particular, such features as the lamination...Full Text Available
We propose a combined experimental (Atomic Force Microscopy) and theoretical study of the structural and dynamical properties of nucleosomes. In contrast to biochemical approaches, this method allows to determine simultaneously the DNA complexed length distribution and nucleosome position in various contexts. First, we show that differences in the nucleo-proteic structure observed between conventional H2A and H2A.Bbd variant nucleosomes induce quantitative changes in the in the length distribution of DNA complexed with histones. Then, the sliding action of remodeling complex SWI/SNF is characterized through the evolution of the nucleosome position and wrapped DNA length mapping. Using a linear energetic model for the distribution of DNA complexed length, we extract the net wrapping energy of DNA onto the histone octamer, and compare it to previous studies.
BackgroundMultilevelness is a defining characteristic of complex systems. For example, in the intestinal tissue the epithelial lining is organized into crypts that are maintained...Full Text Available
The monoanionic bidentate Schiff base, N-(phenolyl)-benzaldimine (HL), has been employed to synthesize a new vanadium(IV) complex of general composition [VO(L)2] (where L = O, N donor of Schiff base). The ligand and complex have been fully characterized by elemental analyses, molar conductance data, FT-IR, 1H- and 13C-NMR, and UV-Vis spectroscopies. Oxidation of alcohols to their corresponding aldehydes and ketones was conducted by this complex catalyst using Oxone as oxidant under biphasic reaction conditions (CH2Cl2/H2O) and tetra-n-butylammonium bromide as phase transfer agent under air at room temperature.
A conserved multi-subunit complex (MybMuvB, MMB), regulates transcriptional activity of many different target genes in Drosophila somatic cells. A paralogous complex, tMAC, controls...Full Text Available
The use of 2-pyridinealdoxime (paoH)/N,N′-donor ligand (L-L) “blend” in cobalt chemistry has afforded two cationic mononuclear cobalt(III) complexes of the general type [Co(pao)2(L-L)]+,...Full Text Available
The palladium(II) and platinum(II)complexes(where, (M(L){sub 2}X{sub 2}), M=Pd(II), Pt(II); L=isoxazole (isox), 3, 5-dimethylisoxazole(3, 5-diMeisox), 3-methyl, 5-phenylisoxazole(3-Me, 5-Ph-isox), and 4-amino-3, 5-di-methylisoxazole (4-ADI); X=Cl, Br) with isoxazole and its derivatives were investigated on antitumor activity by MM2 and EHMO calculation. Because for all the complexes the {sigma}MO energy level (E{sub {sigma}}{sub (M-X)} between d{sub x}{sup 2}{sub -y}{sup 2} orbital of central metal and p{sub x} orbital of halogen atom is less than {sigma}MO energy level E{sub {sigma}}{sub (M-N)} between d{sub x}{sup 2}{sub -y}{sup 2} orbital of central metal and p{sub x} orbital of N atom, without exception. And judging, from the lower E{sub {sigma}}{sub (M-X)} value in trans, the bonding strength was found to be weaker in trans isomer than in cis. For the Pd(II) and Pt(II) complexes which have planar ligands, it was shown ...
Model phosphate-metal solvation complexes have been studied by ab-initio self-consistent-field techniques. The complexes studied include (RO)2PO2-(R = H or CH3) with Li+, Na+, K+, Be++, Mg++, Ca++,...Full Text Available
A new bimetallic complex [HNEt3][Cuq2IEu(hfac)3] (q^- = 8-hydroxyquinolinato, hfac^- = hexafluoroacetylacetonate) was prepared simply with only one step and characterized. Upon excitation of the organic ligand q^-, the sensitized europium luminescence was achieved.
The resistance to microbe damages of aqueous solutions of cutting fluids (SOZh), which contain dual and more complex mixtures of known compounds, is studied. Lauric acid, myristic and tridecanic acid give microbic resistance to the compositions of synthetic cutting fluids. A complexing of the compositions as a rule does not support precisely expressed effects of synergism or antagonism.
Eilatin-containing ruthenium complexes bind to a broad range of different nucleic acids including: calf thymus (CT) DNA, tRNAPhe, polymeric RNAs and DNAs, and viral RNAs including the HIV-1...Full Text Available
Hepatitis C virus NS3-4A is a membrane-bound enzyme complex that exhibits serine protease, RNA helicase, and RNA-stimulated ATPase activities. This enzyme complex is essential for viral genome replication...Full Text Available
RNA interference (RNAi) is an effective tool for studying gene function in oocytes, but no studies have targeted somatic cells of primary cultured cumulus cell-oocyte complexes (COCs). This...Full Text Available
Some acylhydrazine derived ONO donor Schiff bases and their Co(II) and Ni(II) complexes have been prepared having the same metal ion (cation) but different anions. These synthesized metal(II)...Full Text Available
Full text: HMPAO, a butane monoxime derivative of propylene amine and ECD, ethyl cysteinate dimer, are currently being used as brain imaging agents. In an effort to develop new radiopharmaceuticals for imaging brain, we have synthesized amine and imine derivatives of ethyl cysteinate with butane monoxime, optimized labelling procedure with "9"9"mTc and studied the in vivo behaviour of their "9"9"mTc complexes. Imine derivative of ethyl cysteinate with butane monoxime was synthesized by refluxing equimolar amounts of butane monoxime and ethyl cystinate in dry benzene for 3 hours. The product was purified over silica with 10% ethyl acetate in chloroform as eluent. Amine derivative was prepared by reducing the imine derivative with sodium borohydride. The ligands were characterized by NMR spectroscopy and were found to be pure. The ligands were labelled with "9"9"mTc using stannous chloride as reducing agent. The complexes were characterized by ...
MMP, a linear alpha 1 leads to 4 linked polymer of 3-O-methylmannose, regulates the fatty acid synthetase from Mycobacterium smegmatis by forming stoichiometric complexes with the long-chain acyl-CoA...Full Text Available
An examination is made of the structure of the North Saremboyskiy oil field and productive lower Devonian deposits of well 15. Based on detailed lithological studies, as well as investigation of filtering-capacitance properties of rocks, the complex structure of the carbonate deposits and the dominant development of complex type collectors is indicated.
One normally identifies the prediction of tachyons with a higher spin problem. We show that the same phenomenon also happens with certain spin-1/2 equations, in exactly the same circumstances. Furthermore, we prove that these equations also have the defect of possessing solutions with complex energies, even with the smallest external fields. The consequences of these results are analyzed.
The second in a series of flights to assemble the Japanese segment of the International Space Station saw the mammoth Kibo module delivered to the complex complements of Discovery and its crew on the STS-124 mission. Kibo, the Japanese word for u201chopeu201d would house dozens of experiments and serve as a platform for external payloads brought to the complex on subsequent Shuttle flights and the Japanese u201cKounotoriu201d H-2 Transfer Vehicle cargo ship.
Molybdenum dioxo bis acetylacetonate shows a retention of about 31% for both "9"9Mo and "1"0"1Mo, with reactor irradiations at ambient temperature. But its radiolytic stability and resistance to hydrolysis are too low for application to "9"9Mo enrichment. The molybdenum (II) carboxylates and the arene molybdenum (O)tricaronyls show high retentions. These complexes are also air and water sensitive in solution. (orig.).
This thesis contains the candidate's original work on excitonic structure and energy transfer dynamics of two bacterial antenna complexes as studied using spectral hole-burning spectroscopy. The general introduction is divided into two chapters (1 and 2). Chapter 1 provides background material on photosynthesis and bacterial antenna complexes with emphasis on the two bacterial antenna systems related to the thesis research. Chapter 2 reviews the underlying principles and mechanism of persistent nonphotochemical hole-burning (NPHB) spectroscopy. Relevant energy transfer theories are also discussed. Chapters 3 and 4 are papers by the candidate that have been published. Chapter 3 describes the application of NPHB spectroscopy to the Fenna-Matthews-Olson (FMO) complex from the green sulfur bacterium Prosthecochloris aestuarii; emphasis is on determination of the low energy vibrational structure that is important for ...
The annual production of phosphate rock, on the order of about 30-40 million tons yearly, represents several million pounds of uranium. The present invention provides a process of purifying uranium tetrafluoride hydrate to produce a uranium (VI) peroxide product meeting 'yellow cake' standards using a double precipitation procedure. A fluoride complexing agent is used in the precipitation.
French ... Title Synthese d'agregats metalliques par radiolyse de solutions aqueuses de sels simples ou complexes. Etude par M. E. du greffage des agregats sur membranes de carbone.
Dianionic tridentate, O, N, S, Schiff bases derived from salicylaldehyde and 2-mercapto-amines react with Tc(V) gluconate to form radiochemically pure neutral Tc chelates. The existence of lipophilic Tc complexes could be proved by high voltage electrophoresis, thin layer chromatography and octanol/water partition coefficients. 11 refs.
Dianionic tridentate, O, N, S Schiff bases derived from salicylaldehyde and 2-mercapto-amines react with Tc(V) gluconate to form radiochemically pure neutral Tc chelates. The existence of lipophilic Tc complexes could be proved by high voltage electrophoresis, thin layer chromatography and octanol/water partition coefficients. (author).
Anionic complexes of transition metals were stabilized in aqueous solutions containing high concentrations of various short-chain quaternary ammonium salts. Compounds with longer paraffin chains were effective in much less concentrated solution. Complex ions were detected spectrophotometrically. FeCl/sub 4//sup -/, which is usually formed in concentrated HCl, was the predominant Fe(III) complex in 30 m choline chloride containing only 0.12 M HCl. A yellow transitory Tc(VII) chloro-addition intermediate, formed in the reduction of TcO/sub 4//sup -/ by concentrated HCl, was stabilized when the solution also contained 25 m choline chloride. Its spectrum, as well as the isolation of an already known Tc(VII) bipyridyl complex, is reported. Concentrated organic electrolytes also stabilized Tc(V) oxide halides against disproportionation and Tc(IV) hexahalides against hydrolysis. Halochromates of Cr(VI) were ...
A review of main issues in diagnosing, complex treatment and prognosis of Ewing's sarcoma is presented. Current trend in chemotherapy, radiotherapy and surgery of the disease is discussed. Unfavourable prognosis is attributed to the systematic character of the disease, necessitating a complex therapeutic approach. Attempts to make an optimal combination of the three therapeutic methods in order to improve survival and reduce the rate of post-treatment complications are analyzed. 37 refs., 4 tabs. (author).
The sensitivity and specificity of the MGIT TBc identification (TBc ID) test for Mycobacterium tuberculosis complex (MTC) detection in positive Bactec MGIT cultures were 95.2% and 99.2%, respectively. When MTC-positive results obtained from two additional molecular methods were included, the sensitivity of the MGIT TBc ID test was 85.4%, while that of culture was 95.7%. PMID:21450949
Results of americium-242m and americium-242 preparation by irradiating initial americium-241 at a reactor in the form of a diphtalocyanine complex are presented. The enrichment coefficient, equalling 10, has been obtained using the extraction method of recoil atom separation from the parent isotope. Application of the chromatographic column with Dowex-50 permits to increase the enrichment coefficient of isotopes upto 24.6.
Americium 242m and americium 242 were prepared by reactor irradiation of americium 241 as its diphthalocyanine complex. The product atoms were extracted from the parent isotope at an enrichment factor of 10. A Dowex 50 chromatographic column raised the factor to 24.6.
Americium 242m and americium 242 were prepared by reactor irradiation of americium 241 as its diphthalocyanine complex. The product atoms were extracted from the parent isotope at an enrichment factor of 10. A Dowex 50 chromatographic column raised the factor to 24.6.
The structure of a fragment of the germanium complex compound (GCC) with oxyethylidenediphosphonic acid and the adsorption properties of GCC films with respect to the vapors of water and some other organic liquids have been studied. The electric conductivity of GCC films has been investigated, and its mechanism has been explained.
A synergistic effect exists when benzotriazole (BTAH) and iodide ions are used together to prevent the corrosion of copper in sulfuric acid. The nature of this effect has been studied systematically by using electrochemical techniques and X-ray photoelectron spectroscopy. The synergistic effect is due largely to the formation of a film of Cu(IBTA) complex and is probably polymeric in nature. This new complex film greatly depresses copper dissolution.
Computing Networks (CNs) are defined. These are used to generalize neural and swarm architectures, namely artificial neural networks, ant colony optimization, and particle swarm optimization. The description of these architectures as CNs allows their comparison, distinguishing which properties enable them to perform complex computations and exhibit complex cognitive abilities. In this context, the most relevant characteristics of CNs are the existence multiple dynamical and functional scales.
We analyze large diffusion-limited aggregates and uncover a {ital discrete} scaling invariance in their inner structure, which can be quantified by the introduction of a set of {ital complex} fractal dimensions. We provide a theoretical framework and prediction of their values based on renormalization group theory and a previous wavelet analysis. {copyright} {ital 1996 The American Physical Society.}
Nitrogen-fixing microbial populations in a Douglas fir forest on the western slope of the Oregon Cascade Mountain Range were analyzed. The complexity of the nifH gene pool (nifH...Full Text Available
The structures of bromocopper(II) complexes in methanolic (M1, M2, M3, M4), ethanolic (E), and aqueous (H) solutions were determined by the analyses of the Cu K- and Br K-edge EXAFS spectra using a curve-fitting method. The molar concentrations of Cu and Br in these solutions prepared by CuBr_2 and LiBr are 0.996 and 1.992 (M1), 1.015 and 5.381 (M2), 0.493 and 4.525 (M3), 0.260 and 4.073 (M4), 1.031 and 4.313 (E), and 0.982 and 5.426 (H). In M1 solution the interatomic distances for the Cu-O_e_q, Br_e_q-Cu, and Br_e_q-O_e_q (_e_q = equatorial) were 2.00A, 2.35A, and 3.15A respectively, and the Br_e_q-Cu-O_e_q angle was estimated as about 92 deg. Therefore, trans-dibromo bis(methanol)copper(II) complex with a slightly distorted planar structure was proposed to be dominant complex species in M1 solution. The interatomic distances in M2, M3, M4 and E solutions were 2.37A and 3.45A (average) for the Br_e_q-Cu and Br_e_q-Br_e_q ...
The great medieval settlement of Angkor in Cambodia [9th–16th centuries Common Era (CE)] has for many years been understood as a “hydraulic city,” an urban complex defined, sustained,...Full Text Available
By treatment of ?-substituted acetylacetone derivatives with boron trifluoride etherate a series of earlier unknown boron difluoride complexes is obtained. The series includes binuclear complexes containing boron in the chelate fragment connected via sulfur or selenium atom. Gas chromatographic and spectral characteristics of the obtained compounds were investigated. By means of chromato-mass spectrometry their reaction with hydrazine in acidic and alkaline media was studied
The bioenergetic capacity of skeletal muscle in a 17-year-old patient with a severe defect in complex III of the electron transport chain has been examined by 31P NMR measurements of the molar ratio...Full Text Available
Bis(imido) uranium(VI) trans- and cis-dichalcogenate complexes with the general formula U(NtBu)2(EAr)2(OPPh3)2 (EAr = O-2-tBuC6H4, SPh, SePh, TePh) and U(NtBu)2(EAr)2(R2bpy) (EAr = SPh, SePh, TePh) (R2bpy = 4,4'-disubstituted-2,2'-bipyridyl, R = Me, tBu) have been prepared. This family of complexes includes the first reported monodentate selenolate and tellurolate complexes of uranium(VI). Density functional theory calculations show that covalent interactions in the U-E bond increase in the trans-dichalcogenate series U(NtBu)2(EAr)2(OPPh3)2 as the size of the chalcogenate donor increases and that both 5f and 6d orbital participation is important in the M-E bonds of U-S, U-Se, and U-Te complexes.
The Schiff base ligand, 4-isopropylbenzaldehyde[N-(3-oxo-3,4-dihydro-2-quinoxalinyl)hydrazone] (Ipbh), the 1:1 condensation product of 4-isopropylbenzaldehyde and 2-hydroxy-3-hydrazinoquinoxiline, has been synthesized and characterized by X-ray crystallography. A series of complexes of Ipbh with Nickel(II), viz., [Ni(Ipbh)2]Cl2 (1), [Ni(Ipbh)2]Br2 (2), [Ni(Ipbh)2]I2 (3), [Ni(Ipbh)2(CH3OH)2](NO3)2(CH3OH)2 (4) and [Ni(Ipbh)2ClO4]ClO4 (5) have been synthesized. All the complexes were characterized by elemental analysis, molar conductivity, CHN analysis, spectroscopic studies, magnetic susceptibility measurements and TG/DTA methods. The solid-state structure of the complex 4 was established by single crystal X-ray crystallography. In all the complexes, Ipbh acts as a bidentate NO chelating age...
Copper(II) complex coordinated with cyclam-type macrocyclic tetramine, C-meso-1,5,8,12-tetramethyl-1,4,8,11-tetraazacyclotetradecane (2Cdmc) has been synthesized and characterized by single crystal X-ray crystallographic analysis and UV?Vis absorption spectra. Solved molecular structure of [Cu(2Cdmc)(H2O)]Cl2?2H2O (1) revealed that macrocyclic ligand 2Cdmc was in the most stable trans-III structure, but the C-methyl groups of 2Cdmc adopted energetically unfavorable axial configuration (C-axial). This complex 1 is the second example of complex of cyclam-type tetramine with only axially oriented C-methyl groups. This complex adopted five-coordinated square-pyramidal geometry with one water molecule occupying one of the two apical sites. Network of hydrogen bonds involving counter anions (Cl?...
Reaction between [V^I^VO(acac)2] and the ONN donor Schiff base Hpydx-aepy (I) (Hpydx-aepy=Schiff base obtained by the condensation of pyridoxal and 2-aminoethylpyridine) resulted in the formation of a complex [V^I^VO(acac)(pydx-aepy)] (1). Addition of aqueous 30% H2O2 to 1 yields the poor stable oxidoperoxidovanadium(V) complex [V^VO(O2)(pydx-aepy)] (2). Its formation has also been demonstrated in solution by treating 1 with H2O2 in methanol. Reaction of vanadium exchanged zeolite-Y with I in methanol followed by aerial oxidation gave zeolite-Y encapsulated dioxidovanadium(V) complex, abbreviated as [V^VO2(pydx-aepy)]-Y (4). The crystal and molecular structure of 1 has been determined, confirming the ONN binding mode of the ligand. The encapsulated complex [V^VO2(pydx-aepy)]-Y (4) catalyse...
A series of (diamine)isopropylidenmalonatoplatinum(II) complexes and the oxidation products, (diamine)Pt(OOC){sub 2}C=C(CH{sub 3}){sub 2}(X){sub 2}, (diamine=ethylenediamine(en), 1,2-diaminopropan(dap), N-methylethylenediamine(men); X=OH, OCOCH{sub 3}, OCOCF{sub 3}), have been prepared, and their interaction with guanosine-5'-monophosphate (5'-GMP) have been examined by means of {sup 1}H NMR spectroscopy. The present platinum(II) complexes have shown to interact with 5'-GMP through N7 coordination in two consecutive steps in a similar way as with cisplatin, but no interaction between the present platinum(IV) complexes and 5'-GMP was observed. However, in the presence of ascorbic acid, the platinum(IV) complexes have been found to interest with 5'-GMP with the reation rate depending on their reduction rate.
Novel complexes of the type (Pt(DACH)(N-R-iminodiacetate)), wherein DACH represents (R,S)- and (R,R)-1,2 diaminocyclohexane and R represents /minus/Me, /minus/EtOH, and /minus/CH/sub 2/Ph groups, have been prepared, purified, and characterized by spectroscopic techniques (/sup 1/H, /sup 13/C, and /sup 195/Pt NMR;MS(FAB);IR) and by the measurement of selected physical properties (pH, pK/sub a/, conductivity, and molecular weights). The data are consistent with the formation of two diastereomeric complexes in unequal proportions in which the N-R-iminodiacetate ligand appears to be bonded as a pseudofacial tridentate chelate. One are of the ligand forms a stable five-membered-ring O,N-chelate while the other arm appears to be involved in ion-pair formation (zwitterion-like) involving the carboxylate anion and the formally positive Pt(II) central metal atom. It has been demonstrated indirectly that an active impurity was present in predictably ...
New Schiff base derivatives (L1 and L2) were prepared by the condensation of 2-hydroxy-3-methoxybenzaldehyde (o-vanillin) and 3-hydroxy-4-methoxybenzaldehyde (iso-vanillin) with 5-methylfurfurylamine. Two new complexes [Ni(L1)2] and [Cu(L1)2] have been synthesized with bidentate NO donor Schiff base ligand (L1). The Ni(II) and Cu(II) atoms in each complex are four coordinated in a square planar geometry. Schiff bases (L1 and L2) and complexes [Ni(L1)2] and [Cu(L1)2] were characterized by elemental analyses, FT-IR, UV-vis, mass and 1H, 13C NMR spectroscopies. The crystal structures of the ligand (L2) and complexes [Ni(L1)2] and [Cu(L1)2] have also been determined by using X-ray crystallographic technique.
New dioxouranium (VI) complexes of Schiff bases derived from orthaminophenol and salicylaldehyde, 5,6-benzosalicyladehyde, orthohydroxyacetophenone, orthohydroxybenzophenone, acetoacetanilide and benzoylacetanilide have been prepared and characterized by elemental analysis, conductance, molecular weight, infrared, electronic spectra and magnetic susceptibility measurements. The schiff bases behave as ONO donor tridentate dibasic ligands. Two types of complexes, viz. UO_2L.CH_3OH and UO_2L_2 (where LH_2 schiff base) have been synthesized. The comlexes are monomers, nonelectrolytes and diamagnetic. The #nu#(C=N), #nu#(C-O) (phenolic), #nu#(C-O)(CH_3OH) and the ligands. The #nu#sub(as)(O = U =0) occurs in the range 885-940 cm"-"1 and U-O bond length lies in the 1.72-1.74 A range. The 1:1 complexes are six-cordinated and 1:2 complexes are eight coordinated. (author).
The complex ghost introduced previously by the present author is studied from a standpoint whether its effects are observable by experiments or not. According to the theory of complex ghost the scattering cross section of two real particles shows some particular properties. It has a kind of resonance peak at a certain energy which does not conform to the Breit-Wigner formula. It has also a peak for a certain energy transfer, if there exist tachyons. The tachyon is a kind of ghost and is allowed to exist in the theory. Using these properties the complex ghosts are expected to be detected by experiments. The recently observed resonance psi(3.1) is supposed to be the complex ghost of photon, since they have the same quantum numbers. If it is assumed, some properties of the resonance known by experiments are explained naturally to a certain extent. Along the same line it is not unnatural to expect that the ...
Platinum complexes play an important role in the development of anticancer drugs. Their cytotoxicity can be influenced by the nature of the leaving ligands, due to the hydrolysis reaction that occurs prior to the binding of the platinum complex to DNA. Also, non-leaving groups such as lipophilic diamines may affect cellular uptake. In this work, we describe the synthesis of platinum(II) complexes having oxalato and long chain aliphatic N-alkyl ethylenediamines as ligands. The products were characterized by elemental analyses, infrared spectroscopy and {sup 1}H, {sup 13}C and {sup 195}Pt NMR spectroscopy. Biological activity was assessed against tumor cell lines (A{sub 549}, B16-F1, B16-F10, MDA-MB-231) and non-tumor cell lines (BHK-21 and CHO). The length of the carbon chain affects the cytotoxicity and the oxalato complexes were less cytotoxic than the respective chloride-containing analogues. (author)
The ruthenium decontamination factor in Purex process falls quickly with recycles of TBP. So it is necessary to change the chemical states of RuNO complexes in order to improve DF_R_u in the uranium purification cycle. The retention of RuNO complexes in TBP-kerosenelaurohydroxamic acid is observed to be quite large in our previous work. Therefore, water-soluble short chain hydroxamic acid is used as complexing agent to decrease the distribution coefficient of Ru. Hydroxamic acid can transform RuNO complexes into in-extractable species by TBP-kerosene in certain conditions. The result of cascade experiment indicates that the ruthenium decontamination can be increased by a factor of 40-50. Acidity has more influence on the effect of pretreatment. The higher acidity is, the worse the effect will be. The pretreatment is first carried out in low acidic solution, then extractive acidity is increased. In this ...
Two sup(99m)Tc complexes of (N-piperidinylethyl) hexamethyl diaminodithiol (NEP-DADT) have shown high brain uptake in rodents and lower primates. One of these sup(99m)Tc complexes has given positive images of the brain in man which are qualitatively related to regional brain blood flow (rCBF). In order to determine the structure of these sup(99m)Tc products, the corresponding /sup 99/Tc(NEP-DADT) complexes were prepared and characterized by HPLC, TLC, fast-atom-bombardment mass spectrometry (FAB MS) and other analytical techniques. These results indicate that the two /sup 99/Tc (NEP-DADT) complexes are syn and anti isomers (i.e. one isomer has the N-piperdinylethyl side chain located syn to the technetium oxo core while the other has this side chain located anti to the technetium oxo core).
Two sup(99m)Tc complexes of (N-piperidinylethyl) hexamethyl diaminodithiol (NEP-DADT) have shown high brain uptake in rodents and lower primates. One of these sup(99m)Tc complexes has given positive images of the brain in man which are qualitatively related to regional brain blood flow (rCBF). In order to determine the structure of these sup(99m)Tc products, the corresponding "9"9Tc(NEP-DADT) complexes were prepared and characterized by HPLC, TLC, fast-atom-bombardment mass spectrometry (FAB MS) and other analytical techniques. These results indicate that the two "9"9Tc (NEP-DADT) complexes are syn and anti isomers (i.e. one isomer has the N-piperdinylethyl side chain located syn to the technetium oxo core while the other has this side chain located anti to the technetium oxo core). (author).
Paper describes a new procedure to synthesize a pharmaceutical containing "2"1"1At. "2"1"1At"- anion was found to bind strongly with Rh"3"+ cation complexing with a thio-ether ligand - 1,5,9,13-tetratiacyclohexadecane-3,11-diol (16-S4-diol). One made use of "1"3"1I isotope to seek for the optimal conditions of the reaction. The derived complexes were studied by means of the paper electrophoresis, the ion exchange, the surface chromatography. One studied the kinetics of "1"3"1I"- anion binding with Rh(16-S4-diol), the dependence of the yield of "1"3"1I-Rh(16-S4-diol) forming complex on the temperature. the acidity of the reaction mixture and the concentration of the reagents. On the basis of the determined conditions of the synthesis one prepared "2"1"1At-Rh(16-S4-diol) complex by more astatide ("2"1"1At"-) to the equivalent amounts of RhCl_3 and tetra-thio-ether (16-S4-diol). One studied its behaviour
One- and two-dimensional NMR techniques have been used to investigate the solution structures of (2S,6S,11S,15S)-2,6,11,15-tetramethyl-1,4,7,10,13,16-hexaoxacyclooctadecane (I) and (2R,3R,11R,12R)-2,3,11,12-tetramethyl-1,4,7,10,13,16-hexaoxyacyclooctadecane (II) macrocycle complexes of CaCl{sub 2} and Ca(NO{sub 3}){sub 2} in CDCl{sub 3}. Previous chiroptical studies of these and similar crown complexes by circularly polarized luminescence (CPL), total luminescence (TL), and circular dichroism (CD) spectroscopy have shown that the macrocycle asymmetric carbons in these complexes constrain the ring such that the sense of the ring twist in the S chiral ring complexes is opposite to that in the R chiral ring complexes. These studies have also shown that there is an added chirality element in the di- and trivalent (alkaline earth and lanthanide metal, respectively) nitrate ...
The grant in question, DE-FG03-94ER75954, was awarded to Insights El Paso Science Museum to build key exhibits. These exhibits helped the Museum fulfill its mission to ``promote curiosity and stimulate interest by exploratory, entertaining, exciting, and participatory learning in a broad range of scientific disciplines to persons of all ages regionally and internationally.`` There are several current Board of Directors members who also were Board members during the grant period and who helped construct some of the exhibits. Through speaking with them and reviewing minutes of Board meetings during 1994, it has been determined that seven of the ten proposed exhibits were constructed, with an eighth exhibit constructed as an alternative. Photos of seven of the exhibits and preliminary sketches of some are attached. Following is a list of the constructed exhibits: Hot or Cold, Give and Take, Conduction, Convection, Sources of Energy, Wind Generator, Solar Tracker, and ...
Transmission electron microscope (TEM) specimens are today routinely prepared using focussed ion beam (FIB) instruments. Specifically, the lift-out method has become an increasingly popular technique and involves removing thin cross-sections from site-specific locations and transferring them to a TEM grid. This lift-out process can either be performed ex situ or in situ. The latter is mainly carried out on combined dual-beam FIB and scanning electron microscope (SEM) systems whereas conventional single-beam instruments often are limited to the traditional ex situ method. It is nevertheless desirable to enhance the capabilities of existing single-beam instruments to allow for in situ lift-out preparation to be performed since this technique offers a number of advantages over the older ex situ method. A single-beam FIB instrument was therefore modified to incorporate an in situ micromanipulator fitted with a tungsten needle, which can be attached to a cut-out FIB ...
A study examined the concept of interpersonal communication competence in order to construct a more refined instrument than those currently used to measure competence. Using 70 items drawn from several existing measures of competence, 660 volunteer subjects from undergraduate communication courses at a large midwestern university provided their conception of adept and inept communicators, defined respectively as the best and worst communicators they know. Direct and multiple step-wise discriminant analyses were performed to determine the extent to which these items best discriminated between subjects' conceptions of adept and inept communicators, and to determine which of the 70 items best discriminated between these conceptions. Canonical discriminant functions revealed that the subjects clearly distinguished between adept and inept communicators. Classification results revealed that nearly 97% of the cases were classified correctly. Results of the multiple step-wise discriminant ...
This work showed the formation of phospholipid vesicle coating on inorganic sericite surface with characterization by combining electron microscopy of FE-SEM, TEM, AFM, and qualitatively evaluated the coated phospholipid vesicle by XPS as a function of etching time. The possibility of phospholipid vesicle mobility on the surface was restrained by the chelation effect of magnesium cation. The stabilization properties of phospholipid vesicles on sericite surface were demonstrated by the various concentration of magnesium cation. The presence of magnesium was found to have a much more pronounced influence on the lipid deposition process. The Mg cation plays an important role for attaching the phospholipids with optimum concentration of 7 mM. Totally, the phospholipid vesicles coating on inorganic powder could be useful for bio-related fields such as cosmetics and drug delivery system as the key functional compounds. We hope this basic result lead to a general and ...
One of the main objectives of the Finnish Research Programme on Climate Change (SILMU) has been to assess the possible impacts of future changes in climate due to the enhanced greenhouse effect on natural systems and human activities in Finland. In order to address this objective, it was first necessary to specify the types of climate changes to be expected in the Finnish region. Estimates of future climate are conventionally obtained using numerical models, which simulate the evolution of the future climate in response to radiative forcing due to changes in the composition of the atmosphere (i.e. of greenhouse gases and aerosols). However, there are large uncertainties in the model estimates because current knowledge and understanding of atmospheric processes remains incomplete. Since accurate predictions of climate change are not available, an alternative approach is to develop scenarios. These are plausible projections which reflect the best estimates to the future conditions but at ...
We report the radiation exposure dose received by the anesthesiologist and nurse in the orthopaedic operating room, when a fluoroscopic image intensifier is in use. This study was done in 12 femoral neck fracture operations performed from January to May 1995. Radiation was monitored with the MYDOSE MINIX PDM 107 made by Aloka Co. which were attached in front and behind the nurse's lead apron, in front of the lead apron of the anesthesiologist. The average imaging time was 9.78 min. The average radiation dose in front of the anesthesiologist is lead apron was 2.08#mu#SV, and in front and behind the nurse's lead apron were 5.67#mu#SV, 0.08#mu#SV respectively. This study and review of the literature indicate that the operating room anesthesiologist and nurse receive a lower exposure than the orthopaedist. We can disregard the problem of radiation exposure to the anesthesiologist and nurse during an orthopaedic operation when they wear lead aprons and stand far from ...
Focused ion beam (FIB) irradiation of a thin Ni_2Si layer deposited on a Si substrate was carried out and studied using an in-situ transmission electron microscope (in-situ TEM). Square areas on sides of 4 by 4 and 9 by 9 microm were patterned at room temperature with a 25 keV Ga"+-FIB attached to the TEM. The structural changes of the films indicate a uniform milling, sputtering of the Ni_2Si layer and the damage introducing to the Si substrate. Annealing at 673 K results in the change of the Ni_2Si layer into an epitaxial NiSi_2 layer outside the FIB irradiated area, but several precipitates appear around the treated area. Precipitates was analyzed by energy dispersive X-ray spectroscopy (EDS). Larger amount of Ni than the surrounding matrix was found in precipitates. Selected area diffraction (SAD) patterns of the precipitates and the corresponding dark field images imply the formation of a Ni rich silicide. The relation between the FIB tail and the ...
A thermoluminescence (TL) sheet and its spatial readout system for in vivo measurement of spatial dose distribution around sources has been newly developed for intracavitary high dose-rate radiation therapy. The TL sheet (40 cm x 50 cm x 200 {mu}m), which is composed of teflon mixed with BaSO{sub 4} (Eu doped) powder, has a linear response with a very wide dynamic range from at least 0.002 cGy to 5000 cGy for {sup 60}Co sources. Phantom test of the TL sheet readout system demonstrated that absorbed dose with TL sheet and that with ionization chamber as standard dosimeter agreed well. For clinical application, TL sheet was attached on an applicator of intracavitary radiation therapy for rectal cancer. After irradiation with high dose-rate {sup 60}Co sources, the in vivo dose distribution on the surface of the rectum was determined. The TL sheet was suggested to provide a convenient means of measuring the dose distribution around {sup 60}Co sources in intracavitary ...
Forty cases of Ewing's sarcoma of various sites had attended the Department of Radiotherapy at the Wanless Hospital and the Miraj Medical Centre, attached to the Government Medical College, Miraj, Maharashtra, from January, 1970 through December, 1979. There were 28 male patients and 12 female patients in the series with a male to female ratio of 2.3:1. The youngest patient in the series was a female of 6 years of age with the tumour in the scapula and the oldest patient was a 32-year-old male with a lesion in the metacarpal bone. Sixty per cent of the cases were seen in the second decade. The average age of the patients was 13.5 years. The bones of the lower extremities were most commonly involved with the highest number (35 per cent) of the cases occurring in the femur. Involvement of the bones of the right side of the body was almost equal to that of the left side. Swelling over the site of the lesion and pain over the swelling were the most common complaints ...
Purpose: To effectively cool the reactor core in a steam atmosphere by upwardly directing several of spray nozzles attached to a ring header thereby increasing the flying distance of the spray. Constitution: Ring headers in two upper and lower stages are disposed above the outer circumference of a reactor core and each of the ring headers is mounted with spray nozzles. Among the spray nozzles, at least several nozzles mounted to the ring header at the lower stage are directed such that the center axis for each of the nozzle is raised above the horizontal axis and other several nozzles are mounted with the nozzle center axis directed downwardly from the horizontal axis. Accordingly, even if collapsing phenomenon occurs in the jetting stream due to the condensation in the steams that forms the operation atmosphere of the reactor core spray cooling device, a sufficient amount of emergency cooling water can be distributed over the entire reactor core region since the ...
This paper presents direct measurements of the aerodynamic forces on the wing of a free-flying, insect-like ornithopter that was modeled on a hawk moth (Manduca sexta). A micro differential pressure sensor was fabricated with micro electro mechanical systems (MEMS) technology and attached to the wing of the ornithopter. The sensor chip was less than 0.1% of the wing area. The mass of the sensor chip was 2.0 mg, which was less than 1% of the wing mass. Thus, the sensor was both small and light in comparison with the wing, resulting in a measurement system that had a minimal impact on the aerodynamics of the wing. With this sensor, the 'pressure coefficient' of the ornithopter wing was measured during both steady airflow and actual free flight. The maximum pressure coefficient observed for steady airflow conditions was 1.4 at an angle of attack of 30"0. In flapping flight, the coefficient was around 2.0 for angles of attack that ranged from 25"0 to 40"0. Therefore, a ...
This project is concerned with the structure and function of the unique antenna system found in the green photosynthetic bacteria. The antenna system in these organisms is contained within a vesicle known as a chlorosome, which is attached to the cytoplasmic side of the cell membrane. Additional antenna pigments and reaction centers are contained in integral membrane proteins. Energy absorbed by the bacteriochlorophyll c (BChl c) pigments in the chlorosome is transferred via a ``baseplate`` array of BChl a antenna pigments into the membrane and to the reaction center. This system is similar in some respects to the phycobilisome antenna system found in cyanobacteria and some types of algae, in that a membrane-associated structure absorbs light and transfers it to the membrane where conversion to chemical energy takes place. However, the overall structure, the type of pigments utilized and the nature of the proteins in these two types of membrane-associated antenna ...
This paper presents a novel organization of switch capacitor charge pump circuits based on voltage doubler structures. Each voltage doubler takes a DC input and outputs a doubled DC voltage. By cascading voltage doublers the output voltage increases up to 2 times. A two-phase voltage doubler and a multiphase voltage doubler structures are discussed and design considerations are presented. A simulator working in the Q-V realm was used for simplified circuit level simulation. In order to evaluate the power delivered by a charge pump, a resistive load is attached to the output of the charge pump and an equivalent capacitance is evaluated. To avoid the short circuit during switching, a clock pair generator is used to achieve multi-phase non-overlapping clock pairs. This paper also identifies optimum loading conditions for different configurations of the charge pumps. The proposed charge-pump circuit is designed and simulated by SPICE with TSMC 0.35-#mu#m CMOS ...
The social work literature is replete with studies evaluating social workers' direct practice interventions, but strikingly few have assessed how well social workers are faring in the political arena. This study tests a major theoretical model, the civic voluntarism model, developed to explain why some citizens become involved in politics, whereas others do not. The study sample consisted of 396 randomly selected social workers licensed in 11 states, all of whom completed a 25-minute telephone survey. Social workers were surveyed to determine the role of the following variables in explaining social workers' political activity levels--resources needed to participate, psychological engagement, and attachment to recruitment networks. The results indicate that the civic voluntarism model was significant and accounted for 42 percent of the variance. The strongest predictors of social workers' political activity were NASW membership and political interest. This study ...