WorldWideScience
1

A Habitat-Based Model for the Spread of Hantavirus Between Reservoir and Spillover Species  

UK PubMed Central (United Kingdom)

New habitat-based models for spread of hantavirus are developed which account for interspecies interaction. Existing habitat-based models do not consider interspecies pathogen transmission,...Full Text Available

2009-10-21

3

The treatment of diabetic foot infections: focus on ertapenem  

UK PubMed Central (United Kingdom)

Clinically, 3 distinct stages of diabetic foot infection may be recognized: localized infection, spreading infection and severe infection. Each of these presentations may be complicated by osteomyelitis....Full Text Available

2009-01-01

4

Adherence with isoniazid for prevention of tuberculosis among HIV-infected adults in South Africa  

UK PubMed Central (United Kingdom)

BackgroundTuberculosis (TB) is the most common opportunistic infection in HIV-infected adults in developing countries. Isoniazid (INH) is recommended for treatment of latent TB infection,...Full Text Available

5

Exploring the patterns and causes of land use changes in south-west Sweden  

British Library Electronic Table of Contents (United Kingdom)

To study the causes of agricultural declines in south-west Sweden, a multi-proxy study including pollen analysis, bog surface wetness indicators and aeolian sediment influx reconstructions was carried out on the Store Mosse Bog, situated on the coastal plain of Halland. Patterns of agricultural changes during the past 6,000?years from this study were compared to one additional site on the coastal plain (Undarsmosse Bog) and to four sites in the forested upland region. First, we compared land use activity on the coastal plain and in upland regions of south-west Sweden. Three periods with reduced agricultural activities were observed, primarily in records from the coastal plain. Next, the causes for these declines were studied by comparing land use indicators in the pollen records from the S...

2011-01-01

6

Study of the Energy Efficiency of the Melting Unit at the Rockwool Company Mineral Wool Process in Skoevde, Sweden.  

Science.gov (United States)

The melting unit, consisting of a water-cooled cupola furnace, afterburner, heat exchanger, air preheater, consumes most of the supplied energy in the rockwool process. The report maps the energy flows and defines factors of merit according to thermodynam...

1979-01-01

7

Implementing a public web based GIS service for feedback of surveillance data on communicable diseases in Sweden  

UK PubMed Central (United Kingdom)

BackgroundSurveillance data allow for analysis, providing public health officials and policy-makers with a basis for long-term priorities and timely information on possible outbreaks...Full Text Available

8

Economic Assessment of the Negative Impacts of Ozone on Crop Yields and Forest Production. A Case Study of the Estate Oestads Saeteri in Southwestern Sweden  

Energy Technology Data Exchange (ETDEWEB)

Ground level ozone concentrations, in combination with the prevailing climate, at the estate Oestads Saeteri in southwestern Sweden were estimated to reduce the yield of wheat and potato ranging between 5% and 10%. Occasionally, in years with the highest ozone concentrations and/or climatic conditions favoring high rates of ozone uptake to the leaves, yield loss levels above 10% may occur. Based on simple extrapolation, these ozone-induced reductions of crop yields at Oestads Saeteri represent a potential total annual yield loss in Sweden in the range of 24.5 million Euro for wheat and 7.3 million Euro for potato, respectively. A simulation of forest growth at Oestads Saeteri predicted that prevailing mean ozone exposure during 1993-2003 had the potential to reduce forest growth by 2.2% and the economic return of forest production by 2.6%. Using this value for extrapolation to the national level, the potential annual economic loss for ...

2005-02-01

9

Asthma, rhinitis, and dermatitis in workers exposed to reactive dyes.  

UK PubMed Central (United Kingdom)

A survey was conducted at 15 textile plants with dyehouses in western Sweden. Employees with a history of work related rhinitis, asthma, or skin symptoms were offered a clinical and immunological investigation...Full Text Available

1993-01-01

10

Detection of aortoarterial graft infections by leukocyte scintigraphy  

Energy Technology Data Exchange (ETDEWEB)

Infections of aortoarterial prostheses are serious, difficult to detect, and difficult to treat. Scintigraphy with indium-111 labeled autologous leukocytes is an accurate noninvasive method of assessing the presence and extent of such an infection. In three cases of aorto-arterial bypass graft infections, the leukocyte study was successful in establishing the diagnosis and in assessing the extent of infection. Other noninvasive diagnostic techniques are useful, but all have serious limitations. The leukocyte study alone appears to be free of likely sources of error.

1983-09-01

11

Rb-Sr age of the Sundsta granite in the Western Pregothian tectonic mega-unit, south-western Sweden  

Energy Technology Data Exchange (ETDEWEB)

The Sundsta granite is a reddish, acidic granite, situated in the Western Pregothian mega-unit in Vaermland, south-western Sweden. Its Rb-Sr whole-rock age is 1566+-39 Ma with an initial ratio 0f 0.705 +-0.003. The region is dominated by grey, migmatized granitoids presumably belonging to the Aamaal-I group which has ages of 1650-1700 Ma. The marked difference in degree of migmatization between these two rock-units may indicate that the intrusion of the Sundsta granite post-dates the main migmatization phase of the Aamaal-I granitoid in this region.

1982-10-25

12

Marketing opportunity for industries/power plants -- the Swedish case  

Energy Technology Data Exchange (ETDEWEB)

This paper describes and analyses the new situation in the electricity market in Sweden and the attendant emergence of a unique marketing opportunity for industries and power plants to capitalize on bioenergy. This recent marketing opportunity, which is based on consumer demand, has come about through a number of recent institutional changes in Sweden that have drastically lowered the transaction costs associated with the purchase of green electricity, i.e. electricity generated in what is classified as an environmentally sound manner. This has created a functioning market for green electricity and products made using green electricity.

1996-12-31

13

Use of Cefoxitin, New Cephalosporin-Like Antibiotic, in the Treatment of Aerobic and Anaerobic Infections  

UK PubMed Central (United Kingdom)

Forty-two patients were treated with intravenous cefoxitin, a new cephamycin antibiotic. These patients had postoperative abdominal sepsis (26), intrathoracic infections (6), urinary tract infections...Full Text Available

1978-12-01

14

Theoretical Design of a Gene Therapy To Prevent AIDS but Not Human Immunodeficiency Virus Type 1 Infection  

UK PubMed Central (United Kingdom)

Recent reports confirm that, due to the presence of long-lived, latently infected cell populations, eradication of human immunodeficiency virus type 1 (HIV-1) from infected patients by using antiretroviral...Full Text Available

2003-09-01

15

The French national prospective cohort of patients co-infected with HIV and HCV (ANRS CO13 HEPAVIH): Early findings, 2006-2010  

UK PubMed Central (United Kingdom)

BackgroundIn France, it is estimated that 24% of HIV-infected patients are also infected with HCV. Longitudinal studies addressing clinical and public health questions related to...Full Text Available

16

Temporal trends in hepatitis B and C infection in family blood donors from interior Sindh, Pakistan  

UK PubMed Central (United Kingdom)

BackgroundHepatitis B (HBV) and C (HCV) infections are a serious global and national public health problem. Earlier studies have reported increasing rates of hepatitis infection...Full Text Available

17

Neonatal E. coli infection alters glial, cytokine, and neuronal gene expression in response to acute amphetamine in adolescent rats  

UK PubMed Central (United Kingdom)

Neonatal bacterial infection in rats alters the responses to a variety of subsequent challenges later in life. Here we explored the effects of neonatal bacterial infection on a subsequent drug...Full Text Available

2010-04-19

18

Misdiagnosed HIV infection in pregnant women: implications for clinical care.  

UK PubMed Central (United Kingdom)

Out of nearly 900 women in a research study of human immunodeficiency virus infection in pregnancy, 8 were subsequently found not to be infected. Misdiagnoses could have resulted from (a) laboratory...Full Text Available

1994-09-01

19

Impact of repeated four-monthly anthelmintic treatment on Plasmodium infection in preschool children: a double-blind placebo-controlled randomized trial  

UK PubMed Central (United Kingdom)

BackgroundHelminth infections can alter susceptibility to malaria. Studies need to determine whether or not deworming programs can impact on Plasmodium infections...Full Text Available

20

Genital HPV infection not a local but a regional infection: experience from a female teenage group.  

UK PubMed Central (United Kingdom)

OBJECTIVES--To investigate the prevalence of human papillomavirus (HPV) infections in a group of female teenagers, and to analyse to what extent HPV DNA was also detectable, in urethra and cervix samples...Full Text Available

1993-02-01

21

Evaluation of ceftriaxone and other antibiotics against Escherichia coli, Pseudomonas aeruginosa, and Streptococcus pneumoniae under in vitro conditions simulating those of serious infections.  

UK PubMed Central (United Kingdom)

In pursuit of an in vitro system capable of reliably predicting the activities of antibiotics in serious infections and in infections occurring in immunocompromised hosts, we evaluated the abilities...Full Text Available

1988-04-01

22

Diagnosis of Plasmodium falciparum infection using a solid-phase radioimmunoassay for the detection of malaria antigens  

UK PubMed Central (United Kingdom)

A serodiagnostic test has been developed for the detection of Plasmodium falciparum in infected blood. Using parasite antigens and infected red blood cells from in vitro...Full Text Available

1980-01-01

23

Characterization of antibodies mediating protection and cure of Trypanosoma musculi infection in mice.  

UK PubMed Central (United Kingdom)

Plasma samples were collected from mice infected with Trypanosoma musculi at different times postinfection and administered to naive recipient mice either before or during T. musculi infection. The...Full Text Available

1985-06-01

24

BK Virus and Human Cancer: Innocent until Proven Guilty  

UK PubMed Central (United Kingdom)

BK virus (BKV) is a polyomavirus that ubiquitously infects the human population. Following a typically subclinical primary infection, BKV establishes a lifelong persistent infection in the kidney...Full Text Available

2009-08-01

25

Activation of the alternate complement pathway in Staph. aureus infective endocarditis and its relationship to thrombocytopenia, coagulation abnormalities, and acute glomerulonephritis.  

UK PubMed Central (United Kingdom)

Twenty-four patients with infective endocarditis (IE) are described, fourteen with Staph. aureus and ten with other organisms. Despite the acute nature of the infection, ten of the fourteen with Staph....Full Text Available

1978-11-01

26

A Murine Model to Study the Antibacterial Effect of Copper on Infectivity of Salmonella Enterica Serovar Typhimurium  

UK PubMed Central (United Kingdom)

This study investigated the effect of copper as an antibacterial agent on the infectivity of Salmonella enterica serovar Typhimurium. Mice were infected orally with a standardized dose...Full Text Available

2011-01-01

27

Nosocomial Vaccinia Infection  

UK PubMed Central (United Kingdom)

Although hospital-associated spread of vaccinia has been reported in the past, there have been no recent reports. This paper describes hospital-associated spread of vaccinia virus infection, supplies...Full Text Available

1976-10-01

28

Legionella Pneumophila Transcriptome during Intracellular Multiplication in Human Macrophages  

UK PubMed Central (United Kingdom)

Legionella pneumophila is the causative agent of Legionnaires’ disease, an acute pulmonary infection. L. pneumophila is able to infect and multiply in both...Full Text Available

29

Efficacy of tilmicosin in the control of experimentally induced Actinobacillus pleuropneumoniae infection in swine  

UK PubMed Central (United Kingdom)

AbstractThe efficacy of tilmicosin administered in the feed to control Actinobacillus pleuropneumoniae infections in pigs was evaluated through a multisite, multitrial...Full Text Available

2004-01-01

30

Dyspepsia Symptoms and Helicobacter pylori Infection, Nakuru, Kenya  

UK PubMed Central (United Kingdom)

The prevalence of Helicobacter pylori infection was studied in 138 patients with dyspepsia in a hospital in Nakuru, Kenya, and in 138 asymptomatic sex- and age-matched controls from...Full Text Available

2003-09-01

31

Do pediatric emergency departments pose a risk of infection?  

UK PubMed Central (United Kingdom)

BackgroundThere is no data documenting the existence of a risk of infection transmission in ambulatory healthcare settings but concern remains. Our objective was to determine the...Full Text Available

32

Biology and outbreaks of Microdiprion pallipes (Hymenoptera; Diprionidae) in Sweden  

Energy Technology Data Exchange (ETDEWEB)

During outbreaks, Microdiprion pallipes (Fall.) is the most destructive of the pine sawflies in Sweden. Its distribution includes most provinces, but damaging outbreaks have until recently occurred only in two inland areas in northern Sweden. These areas are characterised by high elevation, a harsh climate, and slow tree growth. The four recorded outbreak periods showed a 10 year periodicity. Outside these areas, a lesser outbreak occurred in 1988 to 1990, on the east coast (province of Uppland). Outbreak patterns, life history variation, and mortality factors were studied. Factors that may explain the distribution of outbreaks and the population patterns were identified.Experimental and observational evidence on the potential of various factors to influence fecundity, dispersal, and survival was evaluated. In the outbreak areas, there were few major population factors. Parasitism by Rhorus substitutor (Thunb.) was the largest cause of larval ...

1994-01-01

34

Protein expression in white spot syndrome virus infected Penaeus monodon fabricius.  

Science.gov (United States)

White spot syndrome virus (WSSV) is the causative agent of the white spot disease of shrimp. Penaeus monodon were captured from Muttukadu Estuary in Chennai, India, transported to the laboratory and maintained in an aerated system with continuous water circulation-biofiltration. WSSV-free P. monodon were challenged by feeding them only once with WSSV-infected tissues of P. monodon. Cumulative mortality (100%) of the infected individuals was determined. Tissues from infected and uninfected shrimp such as muscles, hepatopancreas, heart, gills and eye tissues (100mg of each) and haemolymph (50 microl) were subjected to SDS-PAGE. In infected muscle tissue, six newly expressed proteins were detected. In infected haemolymph, four new proteins and three intensely expressed high molecular weight proteins were observed. Three intensely expressed high molecular weight proteins were detected ...

2005-06-01

37

ELECTRON MICROSCOPE STUDIES INTO THE ...  

Science.gov (United States)

ELECTRON MICROSCOPE STUDIES INTO THE MORPHOLOGY AND LOCALIZATION OF OMSK HEMORRHAGIC FEVER VIRUS IN INFECTED ...

1966-08-01

39

Antimicrobials in the Management of Post-Irradiation Infection  

Science.gov (United States)

... develops. An alternative approach is the use of non-absorbable antibiot- ics such as polymyxin, neomycin, and bacitracin. ...

2011-05-13

40

Upsetting categories? The consequences of pharmacogenomics for making knowledge-based reimbursement decisions in Sweden  

British Library Electronic Table of Contents (United Kingdom)

This paper contributes to an understanding of pharmacogenomics-in-the-making by foregrounding a regulatory setting in which these technologies must be situated: decision-making about pharmaceutical reimbursement. Health care assessment organizations have been introduced in many countries to systematically address the issue of health care coverage. Using the example of Sweden, the process of deciding reimbursement status is shown to hinge on the creation of stable and clinically feasible categories of patients, diseases and drug responses. Through a series of analogous examples concerning conventional pharmaceuticals, it is argued that current mechanisms for categorizing reimbursable drugs could be upset when pharmacogenomic advances provide a means of making patients more specific objects ...

2010-01-01

41

Natural remedy use in a prospective cohort of breast cancer patients in southern Sweden  

British Library Electronic Table of Contents (United Kingdom)

Abstract Background. Complementary and alternative medicine (CAM) use is common among breast cancer patients. Several CAM therapies may have negative side effects or interact with conventional therapies. We studied biologically based CAM use with and without vitamins/minerals in relation to patient and tumor characteristics as well as treatment in an ongoing prospective cohort of 855 primary breast cancer patients. Methods. Patients from two hospitals in southern Sweden were included. Pre-operative and follow-up questionnaires containing questions on food intake, lifestyle, and concomitant medications, including natural remedies, were completed up to five years postoperatively. Clinical information was obtained from clinical records and tumor characteristics from pathology reports. Results...

2011-01-01

42

Energy from waste: current progress in Sweden  

Energy Technology Data Exchange (ETDEWEB)

Considerable effort worldwide has been put into trying to find the best way to utilise the large amount of energy that we put into our dustbins every day. One of the problems encountered is that the waste collection systems tend to gather together in one place between 400 and 1000 t of the stuff everyday and since it is possible to extract rather more than 2 MW from each tonne, that is a lot of energy for which to find a market. In continental European cities, especially Germany, and Sweden with most of the population living in apartment blocks, and with colder winters than the UK, district heating provides a suitable market. With its milder winters, more diverse housing and cheap gas the UK is not such a fertile ground for district heating. But since the passing of the Energy Act in 1984, there is a steady market in electricity generation with the advantage that the purchase tariffs are published so that income can be accurately calculated.

1988-11-01

43

Cost-effectiveness of a barrier-strengthening moisturizing cream as maintenance therapy vs. no treatment after an initial steroid course in patients with atopic dermatitis in Sweden - with model applications for Denmark, Norway and Finland  

British Library Electronic Table of Contents (United Kingdom)

Abstract Background Atopic dermatitis (AD) affects health and quality of life and it has great impact on both health-care costs and costs to the society. Objectives The objective of this study was to develop a model to analyse the cost-effectiveness of a barrier-strengthening moisturizing cream as maintenance therapy compared with no treatment after initial treatment with betamethasone valerate in adult patients with AD in Sweden. A further aim was to apply a similar health-economic analysis for Denmark, Norway and Finland. Methods A Markov simulation model was developed including data from three sources: (i) efficacy data from a randomized controlled trial including patients with moderate AD treated with either a moisturizing cream or no treatment, (ii) resource utilization and quality of...

2010-01-01

44

Management of septic complications following modular endoprosthetic reconstruction of the proximal femur  

British Library Electronic Table of Contents (United Kingdom)

In a retrospective single-centre study 170 consecutive patients were included who received a Kotz modular prosthesis after resection of bone tumours of the proximal femur to evaluate the management of prosthetic infection. Infection occurred in 12 of 166 patients available for follow-up (six males; six females; mean age, 47?years; range, ten to 75?years) after a mean of 39?months (range, one to 166?months; infection rate, 7.2%). Mean follow-up was 54?months (range, four to 200?months). One patient died of septic shock. Two patients were treated by wound revision only. Treatment of infection in the remaining patients was one-stage revision in eight and hip disarticulation in one. Infection control by one-stage revision was achieved in five of eight patients; re-infection occurred in three p...

2011-01-01

45

Comparative profiling of the transcriptional response to soybean cyst nematode infection of soybean roots by deep sequencing  

British Library Electronic Table of Contents (United Kingdom)

To gain insight into the changes in the transcriptome of soybean roots during soybean cyst nematode (SCN) infection, we conducted genome-wide gene expression profiling using serial analysis of gene expression (SAGE) combined with Solexa sequencing. More than 3 million tags were generated from the SCN-infected and uninfected roots, and 366941 and 314591 clean UniTags were obtained from SCN-infected and uninfected samples, respectively. In the SCN-infected sample, 48249 UniTags represented 18114 reference genes. In the uninfected control, 46290 UniTags represented 19323 reference genes. Comparison of tag frequencies identified 1405 genes that were expressed at greater levels in SCN-infected roots than in uninfected roots, and 1191 genes that were expressed at lower levels. Quantitative real-...

2011-01-01

46

Sweden employs a multi venturi scrubber for containment venting  

Energy Technology Data Exchange (ETDEWEB)

The Filtra-MVSS for filtered venting of containment overpressure is a flexible system capable of covering a wide range of hypothetical design basis events for BWRs and PWRs. The system encompasses a number of special features, can be optimized for a specified decontamination factor, and can accommodate a wide range of off-gas flow rates.

1988-03-01

47

Resources | Environment Knowledge Hub  

Wastenet

...Korea 2008 NOx charges as feebate in Sweden Pilot Project on Solid Waste Management in Khulna City: Community Organisation and Management Plastic Bag ban in Dhaka City, Bangladesh Policies on Conservation of the DMZ District Ecosystem Ministry of Environment Republic of Korea 2007 Policies on Promoting Environmental Industries and International Cooperation ...

48

Research - Keyword Index  

Wastenet

...understanding sweden publication publication market publications publications inco publications library public-private partnerships publishing publishing platform pufafeed puglia pulmonary diseases pulp puma pumped hydro storage pumped storage plants purity purpose purpose-grown energy crops purposes pv pv added value pv cells pv crystalline cells pv organic and polymer cells pv research pv ...

49

Nuclear fuel cycle. V. 2  

International Nuclear Information System (INIS)

Nuclear fuel cycle information in some countries that develop, supply or use nuclear energy is presented. Data about Argentina, Australia, Belgium, Netherlands, Italy, Denmarmark, Norway, Sweden, Switzerland, Finland, Spain and India are included. The information is presented in a tree-like graphic way. (C.S.A.).

1979-06-08

50

Liability problems related to backfitting of nuclear installations in Eastern Europe  

Energy Technology Data Exchange (ETDEWEB)

The paper shortly recapitulates the background to and the importance of the principle of channeling of liability to the operator, contained in the international Conventions in the field of nuclear liability. It tries to outline the main problems involved in the process of backfitting in some more detail and to describe part of the work that has been done in Sweden and elsewhere to try to solve them. Finally, the paper contains some concluding remarks indicating that no entirely satisfactory solution to the problem is presently at hand. (orig./HP)

1995-12-31

51

Developing a regulatory performance assessment approach for geological disposal of spent nuclear fuel  

International Nuclear Information System (INIS)

To be able to carry out review functions regulatory authorities must be able to make critical evaluations of proponent's safety cases. In Sweden the Swedish Radiation Safety Authority aims to have in place its own suite of performance assessment tools. This paper looks at the role and application of a regulator's models to important features of current modelling in a proponent's performance assessment. (authors)

52

Coradia LIREX X 60 for Sweden; Coradia LIREX X 60 fuer Schweden  

Energy Technology Data Exchange (ETDEWEB)

The new power cars currently being built for commuter services in the Stockholm area have a number of innovative features. Manufacturer Alstom-LHB, who developed the vehicle based on experience gained with the LIREX experimental train, is also offering this model in continental Europe. (orig.)

2005-07-01

53

Aerosols Equipment in Sweden on Environmental Expert  

Wastenet

... Hale, Markku Kulmala, 373.43 EUR; 225.00 USD; 276.00 GBP... Light Scattering Media Optics Alexander A. Kokhanovsky 159.00 USD; 123.00 EUR; 103.50 GBP... More Journals » MAGAZINES & JOURNALS Water Policy - Official Journal of the World... Water Policy publishes reviews, research papers... ...

54

Visual Genome-Wide RNAi Screening to Identify Human Host Factors Required for Trypanosoma cruzi Infection  

UK PubMed Central (United Kingdom)

The protozoan parasite Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical infection that affects millions of people in the Americas. Current chemotherapy...Full Text Available

55

Transmitted drug resistance in nonsubtype B HIV-1 infection  

UK PubMed Central (United Kingdom)

HIV-1 nonsubtype B variants account for the majority of HIV infections worldwide. Drug resistance in individuals who have never undergone antiretroviral therapy can lead to early failure and...Full Text Available

2009-09-01

56

The urine dipstick test useful to rule out infections. A meta-analysis of the accuracy  

UK PubMed Central (United Kingdom)

BackgroundMany studies have evaluated the accuracy of dipstick tests as rapid detectors of bacteriuria and urinary tract infections (UTI). The lack of an adequate explanation for...Full Text Available

57

The paradox of using a 7 day antibacterial course to treat urinary tract infections in the community.  

UK PubMed Central (United Kingdom)

1. We have studied determinants of outcome of 7 day courses of treatment in 77 middle aged and elderly patients, in whom the general practitioner's diagnosis of urinary tract infections had been confirmed...Full Text Available

1988-10-01

58

The inhibition of staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection  

UK PubMed Central (United Kingdom)

Peri-prosthetic infections are notoriously difficult to treat as the biomaterial implant is ideal for bacterial adhesion and biofilm formation, resulting in decreased antibiotic sensitivity....Full Text Available

2008-12-01

59

Synergism between Prior Anisakis simplex Infections and Intake of NSAIDs, on the Risk of Upper Digestive Bleeding: A Case-Control Study  

UK PubMed Central (United Kingdom)

BackgroundThe aim of this study was to investigate the relationship between prior Anisakis infections and upper gastrointestinal bleeding (UGIB), and its interaction...Full Text Available

60

Synchronous infection of SIV and HIV in vitro for virology, immunology, and vaccine-related studies  

UK PubMed Central (United Kingdom)

The development of an HIV vaccine will require a more precise understanding of the immunological and virological underpinnings of HIV infection. Magnetofection, the process of magnetizing HIV...Full Text Available

2010-01-01

61

Sustaining reductions in catheter related bloodstream infections in Michigan intensive care units: observational study  

UK PubMed Central (United Kingdom)

Objectives To evaluate the extent to which intensive care units participating in the initial Keystone ICU project sustained reductions in rates of catheter related bloodstream infections.Design...Full Text Available

2010-01-01

62

Susceptibility of human primary neuronal cells to Xenotropic Murine Leukemia Virus-related (XMRV) virus infection  

UK PubMed Central (United Kingdom)

BackgroundXenotropic Murine Leukemia Virus-related (XMRV) virus is a recently identified mouse gammaretrovirus that has the ability to infect certain human cells. In this study,...Full Text Available

63

Substance P Signaling Contributes to Granuloma Formation in Taenia crassiceps Infection, a Murine Model of Cysticercosis  

UK PubMed Central (United Kingdom)

Cysticercosis is an infection with larval cysts of the cestode Taenia solium. Through pathways that are incompletely understood, dying parasites initiate a granulomatous reaction that,...Full Text Available

2010-01-01

64

Serum Prohepcidin Levels in Helicobacter Pylori Infected Patients with Iron Deficiency Anemia  

UK PubMed Central (United Kingdom)

Background/AimsHelicobacter pylori (H. pylori) infection appears to subvert the human iron regulatory mechanism and thus upregulates hepcidin, resulting...Full Text Available

2010-06-01

65

SAMHD1: a new insight into HIV-1 restriction in myeloid cells  

UK PubMed Central (United Kingdom)

Human myeloid-lineage cells are refractory to HIV-1 infection. The Vpx proteins from HIV-2 and sooty mangabey SIV render these cells permissive to HIV-1 infection through proteasomal degradation of...Full Text Available

66

Ross River Virus Transmission, Infection, and Disease: a Cross-Disciplinary Review  

UK PubMed Central (United Kingdom)

Ross River virus (RRV) is a fascinating, important arbovirus that is endemic and enzootic in Australia and Papua New Guinea and was epidemic in the South Pacific in 1979 and 1980. Infection with RRV...Full Text Available

2001-10-01

67

Results of a multicenter trial comparing imipenem/cilastatin to tobramycin/clindamycin for intra-abdominal infections.  

UK PubMed Central (United Kingdom)

We designed a multicenter study to compare tobramycin/clindamycin to imipenem/cilastatin for intra-abdominal infections. We included the Acute Physiology and Chronic Health Evaluation (APACHE II) index...Full Text Available

1990-11-01

68

Randomized Controlled Trials of Interventions to Prevent Sexually Transmitted Infections: Learning From the Past to Plan for the Future  

UK PubMed Central (United Kingdom)

Globally, sexually transmitted infections (STIs) represent a significant source of morbidity and disproportionately impact the health of women and children. The number of randomized controlled trials...Full Text Available

2010-04-01

69

Proteome-wide Anti-HCV and Anti-HIV Antibody Profiling for Predicting and Monitoring Response to HCV Treatment in HIV Co-infected Patients  

UK PubMed Central (United Kingdom)

We quantified antibody responses to the HCV proteome that are associated with sustained virologic response (SVR) in HIV/HCV co-infected patients treated with pegylated interferon and ribavirin....Full Text Available

2010-09-15

70

Prospective Memory in HIV-1 Infection  

UK PubMed Central (United Kingdom)

The cognitive deficits associated with HIV-1 infection are thought to primarily reflect neuropathophysiology within the fronto-striato-thalamo-cortical circuits. Prospective memory (ProM) is...Full Text Available

2006-05-01

71

Prevalence of Erectile Dysfunction in HTLV-1 Infected Patients and its Association with Overactive Bladder  

UK PubMed Central (United Kingdom)

ObjectiveTo determine the prevalence of erectile dysfunction (ED) in HTLV-I infected patients, and its association with overactive bladder (OB).Full Text Available

2010-05-01

72

Polyantigenic Interferon-? Responses Are Associated with Protection from TB among HIV-Infected Adults with Childhood BCG Immunization  

UK PubMed Central (United Kingdom)

BackgroundSurrogate immunologic markers for natural and vaccine-mediated protection against tuberculosis (TB) have not been identified.MethodsHIV-infected...Full Text Available

73

Patient-Care Practices Associated With an Increased Prevalence Of Hepatitis C Virus Infection among Chronic Hemodialysis Patients  

UK PubMed Central (United Kingdom)

ObjectiveTo identify patient-care practices related to an increased prevalence of hepatitis C virus (HCV) infection among chronic hemodialysis patients.Full Text Available

2011-05-01

74

Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity  

UK PubMed Central (United Kingdom)

BackgroundSeasonal influenza A infection affects a significant cohort of the global population annually, resulting in considerable morbidity and mortality. Therapeutic strategies...Full Text Available

2011-05-01

75

Multiplicity of Plasmodium falciparum infection in asymptomatic children in Senegal: relation to transmission, age and erythrocyte variants  

UK PubMed Central (United Kingdom)

BackgroundIndividuals living in malaria endemic areas generally harbour multiple parasite strains. Multiplicity of infection (MOI) can be an indicator of immune status. However,...Full Text Available

76

Multiple integration sites for Moloney murine leukemia virus in productively infected mouse fibroblasts.  

UK PubMed Central (United Kingdom)

The integration sites for viral DNA in cells infected with Moloney murine leukemia virus (M-MuLV) were studied by restriction endonuclease cleavage of cellular DNA followed by electrophoresis in agarose...Full Text Available

1979-06-01

77

Meningococcal infections in the Hamilton area during 1978.  

UK PubMed Central (United Kingdom)

During 1978 there was a marked increase in the number of patients with meningococcal infection in the Hamilton area. Of 21 patients admitted to St. Joseph's Hospital, Hamilton, two thirds were under...Full Text Available

1980-03-08

78

Mechanism of Host Defense Suppression Induced by Viral Infection: Mode of Action of Inosiplex as an Antiviral Agent  

UK PubMed Central (United Kingdom)

The mechanism of influenza virus (INFV)-induced immunosuppression and the mode of inosiplex action against INFV infection were studied. INFV suppressed both anti-lipopolysaccharide and anti-sheep erythrocyte...Full Text Available

1982-10-01

79

Listeria monocytogenes Infection Induces Prosurvival Metabolic Signaling in Macrophages?  

UK PubMed Central (United Kingdom)

Host cells use metabolic signaling through the LXRα nuclear receptor to defend against Listeria monocytogenes infection. 25-Hydroxycholesterol is a natural ligand of LXRs that...Full Text Available

2011-04-01

80

Lethal Silver-Haired Bat Rabies Virus Infection Can Be Prevented by Opening the Blood-Brain Barrier?  

UK PubMed Central (United Kingdom)

Silver-haired bat rabies virus (SHBRV) infection induces a strong virus-specific immune response in the periphery of the host, but death is common due to the failure to open the blood-brain barrier...Full Text Available

2007-08-01

81

Inhibition of HIV-1 Infection in Ex Vivo Cervical Tissue Model of Human Vagina by Palmitic Acid; Implications for a Microbicide Development  

UK PubMed Central (United Kingdom)

BackgroundApproximately 80% of all new HIV-1 infections are acquired through sexual contact. Currently, there is no clinically approved microbicide, indicating a clear and...Full Text Available

82

Influence of parasite strain on chemotherapy of murine infections with schistosomiasis mansoni  

UK PubMed Central (United Kingdom)

The effectiveness of chemotherapy in human schistosomiasis varies from one area to another, and limited data from experimentally infected animals suggest inherent differences in the susceptibility...Full Text Available

1971-01-01

83

Infective arthritis secondary to bladder outflow obstruction.  

UK PubMed Central (United Kingdom)

We describe two cases of septic arthritis occurring in association with lower urinary tract infection in elderly men. In both cases the organism isolated from both the joint and the urine was Staphylococcus...Full Text Available

1990-12-01

84

Infection dynamics and clinical manifestations following experimental inoculation of gilts at 90 days of gestation with a low dose of porcine reproductive and respiratory syndrome virus  

UK PubMed Central (United Kingdom)

Understanding the dynamics of porcine reproductive and respiratory syndrome virus (PRRSV) vertical transmission is important to enhance the accuracy of monitoring protocols for endemically infected...Full Text Available

2009-10-01

85

Individual Predisposition, Household Clustering and Risk Factors for Human Infection with Ascaris lumbricoides: New Epidemiological Insights  

UK PubMed Central (United Kingdom)

BackgroundMuch of our current understanding of the epidemiology of Ascaris lumbricoides infections in humans has been acquired by analyzing worm count data. These...Full Text Available

86

Increased prevalence of Borrelia burgdorferi infections in Bernese Mountain Dogs: a possible breed predisposition  

UK PubMed Central (United Kingdom)

BackgroundGlomerulonephritis in dogs has been associated with B. burgdorferi infections. In Bernese Mountain Dogs with glomerulonephritis antibodies against B....Full Text Available

87

In vitro assay for curative activity in blood of mice infected with Trypanosoma musculi.  

UK PubMed Central (United Kingdom)

An in vitro assay for curative antibody present in plasma of mice cured of Trypanosoma musculi is described. The assay involves the addition of plasma to a sample of infected blood, followed by hourly...Full Text Available

1986-08-01

88

Impact of Long-Term Treatment with Ivermectin on the Prevalence and Intensity of Soil-Transmitted Helminth Infections  

UK PubMed Central (United Kingdom)

BackgroundControl of soil-transmitted helminth (STH) infections relies on the periodic and long-term administration of anthelmintic drugs to high-risk groups, particularly school-age...Full Text Available

89

Identification of immune genes and proteins involved in the response of bovine mammary tissue to Staphylococcus aureus infection  

UK PubMed Central (United Kingdom)

BackgroundMastitis in dairy cattle results from infection of mammary tissue by a range of micro-organisms but principally coliform bacteria and Gram positive bacteria such as Staphylococcus...Full Text Available

90

IL-6-Dependent Mucosal Protection Prevents Establishment of a Microbial Niche for Attaching/Effacing Lesion-Forming Enteric Bacterial Pathogens1  

UK PubMed Central (United Kingdom)

Enteric infections with attaching/effacing lesion-inducing bacterial pathogens are a worldwide health problem. A murine infection model with one such pathogen, Citrobacter rodentium,...Full Text Available

2008-05-15

91

Human papillomavirus infection in Beijing, People's Republic of China: a population-based study  

UK PubMed Central (United Kingdom)

Background:No recent data exist on human papillomavirus (HPV) infection in Beijing, People's Republic of China.Materials and methodWe interviewed...Full Text Available

2009-11-03

92

Human papillomavirus infection and anal carcinoma. Retrospective analysis by in situ hybridization and the polymerase chain reaction.  

UK PubMed Central (United Kingdom)

To examine the association of human papillomavirus (HPV) infection with anal squamous cell carcinoma, the authors applied the highly sensitive polymerase chain reaction (PCR) and in situ hybridization...Full Text Available

1992-06-01

93

Hepatitis B virus infection and primary hepatocellular carcinoma.  

UK PubMed Central (United Kingdom)

For many years, epidemiological studies have demonstrated a strong link between chronic hepatitis B virus (HBV) infection and the development of primary hepatocellular carcinoma (PHC). Other hepatocarcinogens...Full Text Available

1992-07-01

94

Hepatitis B virus infection among different sex and age groups in Pakistani Punjab  

UK PubMed Central (United Kingdom)

BackgroundHepatitis B virus (HBV) infection is a serious health problem in the developing countries including Pakistan. Various risk factors are responsible for the spread of this...Full Text Available

95

Genetic Polymorphism of Cancer Susceptibility Genes and HPV Infection in Cervical Carcinogenesis  

UK PubMed Central (United Kingdom)

It is widely accepted that specific human papillomavirus (HPV) types are the central etiologic agent of cervical carcinogenesis. However, a number of infected women do not develop invasive lesions,...Full Text Available

96

From Attachment to Damage: Defined Genes of Candida albicans Mediate Adhesion, Invasion and Damage during Interaction with Oral Epithelial Cells  

UK PubMed Central (United Kingdom)

Candida albicans frequently causes superficial infections by invading and damaging epithelial cells, but may also cause systemic infections by...Full Text Available

97

Experimental infection of Foxes with European bat Lyssaviruses type-1 and 2  

UK PubMed Central (United Kingdom)

BackgroundSince 1954, there have been in excess of 800 cases of rabies as a result of European Bat Lyssaviruses types 1 and 2 (EBLV-1, EBLV-2) infection, mainly...Full Text Available

98

Enhancing Patient Safety by Reducing Healthcare-Associated Infections: The Role of Discovery and Dissemination  

UK PubMed Central (United Kingdom)

Healthcare-associated infections (HAIs) take a major human toll on society and reduce public confidence in the healthcare system. The current convergence of scientific, public, and legislative...Full Text Available

2010-02-01

99

Effects of bovine leukemia virus infection on production and reproduction in dairy cattle.  

UK PubMed Central (United Kingdom)

The purpose of this study was to determine the effects of bovine leukemia virus (BLV) infection on production, reproduction and longevity in dairy cattle. The study population was a commercial Holstein...Full Text Available

1992-10-01

100

Disruption of Putative Regulatory Loci in Listeria monocytogenes Demonstrates a Significant Role for Fur and PerR in Virulence  

UK PubMed Central (United Kingdom)

The ability to adapt to adverse environmental conditions encountered in food and during host infection is a sine qua non for a successful Listeria monocytogenes infection. This ability...Full Text Available

2004-02-01

101

Desmozoon lepeophtherii n. gen., n. sp., (Microsporidia: Enterocytozoonidae) infecting the salmon louse Lepeophtheirus salmonis (Copepoda: Caligidae)  

UK PubMed Central (United Kingdom)

BackgroundA microsporidian was previously reported to infect the crustacean parasite, Lepeophtheirus salmonis (Krøyer, 1837) (Copepoda, Caligidae), on farmed...Full Text Available

102

Decreased respiratory quotient in relation to resting energy expenditure in HIV-infected and non-infected subjects  

UK PubMed Central (United Kingdom)

The purpose of this study was to evaluate the relationship of respiratory quotient (RQ), a surrogate marker of substrate oxidation, as well as body composition and dietary intake to resting...Full Text Available

2009-05-01

103

Conventional Linear versus Purse-string Skin Closure after Loop Ileostomy Reversal: Comparison of Wound Infection Rates and Operative Outcomes  

UK PubMed Central (United Kingdom)

PurposeWound infection after an ileostomy reversal is a common problem. To reduce wound-related complications, purse-string skin closure was introduced as an alternative to conventional...Full Text Available

2011-04-01

104

Control of intestinal parasitic infections in Seychelles: a comprehensive and sustainable approach.  

UK PubMed Central (United Kingdom)

Intestinal parasitic infections have been perceived as a public health problem in Seychelles for decades. A comprehensive strategy to reduce morbidity and, in the long term, transmission of intestinal...Full Text Available

1996-01-01

105

Comparison of a Commercial Multiplex Real-Time PCR to the Cell Cytotoxicity Neutralization Assay for Diagnosis of Clostridium difficile Infections?  

UK PubMed Central (United Kingdom)

A commercial multiplex real-time PCR assay (Cepheid Xpert C. difficile assay) for the diagnosis of Clostridium difficile infection was evaluated. The sensitivity and...Full Text Available

2009-11-01

106

Circulating Matrix Metalloproteinases in Infective Endocarditis: A Possible Marker of the Embolic Risk  

UK PubMed Central (United Kingdom)

BackgroundEmbolic events (EE) in infective endocarditis (IE) are caused by fragmentation of vegetations or valvular tissue. Vegetation length is considered to be the most potent...Full Text Available

107

Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil  

UK PubMed Central (United Kingdom)

In world Helminthes infections are the most widespread of all the infections in humans. The morbidity due to parasitic diseases has been increasing in our population. The gastrointestinal helminthes...Full Text Available

2010-05-01

108

Chlamydial urethral infection in Teheran. A study of male patients attending an STD clinic.  

UK PubMed Central (United Kingdom)

The prevalence of chlamydial infection of the urethra was studied in 172 consecutive male patients attending a sexually transmitted disease clinic in Teheran. Chlamydia trachomatis was isolated in 8.8%...Full Text Available

1982-12-01

109

Characterization of the Molecular Mechanism of Defective Interfering RNA-Mediated Symptom Attenuation in Tombusvirus-Infected Plants  

UK PubMed Central (United Kingdom)

Different tombusviruses were able to support the replication of either homologous or heterologous defective interfering (DI) RNAs, and those infected plants usually developed typical attenuated symptoms....Full Text Available

1998-07-01

110

CTX-M ?-Lactamases in Escherichia coli from Community-acquired Urinary Tract Infections, Cambodia  

UK PubMed Central (United Kingdom)

Despite the recent global spread of CTX-M β-lactamases in Escherichia coli isolates from community-acquired urinary tract infections (CA-UTIs), their dissemination has been...Full Text Available

2009-05-01

111

Bone Disease in HIV Infection: A Practical Review and Recommendations for HIV Care Providers  

UK PubMed Central (United Kingdom)

Low bone mineral density (BMD) is prevalent in human immunodeficiency virus (HIV)–infected subjects. Initiation of antiretroviral therapy is associated with a 2%–6% decrease...Full Text Available

2010-10-15

112

Asymptomatic gonorrhoea and chlamydial infection in rural Tanzanian men.  

UK PubMed Central (United Kingdom)

OBJECTIVE: To measure the prevalence of urethritis due to Neisseria gonorrhoeae and Chlamydial infection trachomatis in rural Tanzanian men DESIGN: About 500 men aged 15-54 years were selected from...Full Text Available

1996-02-03

113

Association of Nasophyaryngeal Bacterial Colonization during Upper Respiratory Tract Infection and the Development of Acute Otitis Media  

UK PubMed Central (United Kingdom)

Acute Otitis Media occurs mostly after upper respiratory tract infection; the causative bacteria are those colonized in the nasopharynx. We studied 709 URI episodes and found that children with...Full Text Available

2008-02-15

114

Association between skin diseases and severe bacterial infections in children: case-control study  

UK PubMed Central (United Kingdom)

BackgroundSepsis or bacteraemia, however rare, is a significant cause of high mortality and serious complications in children. In previous studies skin disease or skin infections...Full Text Available

115

Association between bacterial vaginosis or chlamydial infection and miscarriage before 16 weeks' gestation: prospective community based cohort study  

UK PubMed Central (United Kingdom)

ObjectivesTo assess whether bacterial vaginosis or chlamydial infection before 10 weeks' gestation is associated with miscarriage before 16 weeks.DesignProspective...Full Text Available

2002-12-07

116

Aspirin Treatment of Mice Infected with Trypanosoma cruzi and Implications for the Pathogenesis of Chagas Disease  

UK PubMed Central (United Kingdom)

Chagas disease, caused by infection with Trypanosoma cruzi, is an important cause of cardiovascular disease. It is increasingly clear that parasite-derived prostaglandins potently modulate...Full Text Available

117

Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing).  

UK PubMed Central (United Kingdom)

The mammalian reoviruses have provided a valuable model for studying the pathogenesis of viral infections of the central nervous system (CNS). We have used this model to study the effect of antibody...Full Text Available

1988-12-01

118

Accumulation of Plasmodium berghei-Infected Red Blood Cells in the Brain Is Crucial for the Development of Cerebral Malaria in Mice?  

UK PubMed Central (United Kingdom)

Cerebral malaria is the most severe complication of human infection with Plasmodium falciparum. It was shown that Plasmodium berghei ANKA-induced cerebral malaria was...Full Text Available

2010-09-01

119

ABO blood group phenotypes influence parity specific immunity to Plasmodium falciparum malaria in Malawian women  

UK PubMed Central (United Kingdom)

BackgroundBlood group O has been significantly associated with increased placental malaria infection in primiparae and reduced risk of infection in multiparae in the Gambia, an area...Full Text Available

120

A population pharmacokinetic meta-analysis of maraviroc in healthy volunteers and asymptomatic HIV-infected subjects  

UK PubMed Central (United Kingdom)

AimsTo develop a population pharmacokinetic model for maraviroc, a noncompetitive CCR5 antagonist, after oral administration of tablets to healthy volunteers and asymptomatic HIV-infected...Full Text Available

2008-04-01

121

A Simple, Versatile and Sensitive Cell-Based Assay for Prions from Various Species  

UK PubMed Central (United Kingdom)

Detection and quantification of prion infectivity is a crucial step for various fundamental and applied aspects of prion research. Identification of cell lines highly sensitive to prion infection led...Full Text Available

122

Neuroinflammation and brain infections: Historical context and current perspectives  

British Library Electronic Table of Contents (United Kingdom)

An overview of current concepts on neuroinflammation and on the dialogue between neurons and non-neuronal cells in three important infections of the central nervous systems (rabies, cerebral malaria, and human African trypanosomiasis or sleeping sickness) is here presented. Large numbers of cases affected by these diseases are currently reported. In the context of an issue dedicated to Camillo Golgi, historical notes on seminal discoveries on these diseases are also presented. Neuroinflammation is currently closely associated with pathogenetic mechanisms of chronic neurodegenerative diseases. Neuroinflammatory signaling in brain infections is instead relatively neglected in the neuroscience community, despite the fact that the above infections provide paradigmatic examples of alterations o...

2011-01-01

123

Evidence-Based Drainage of Infected Hydronephrosis Secondary to Ureteric Calculi  

British Library Electronic Table of Contents (United Kingdom)

Abstract Introduction: The obstructed, infected kidney is a urological emergency. It has been accepted that the management of infected hydronephrosis secondary to ureteric stones is through prompt decompression of the collecting system. However, the optimal method of decompression has yet to be established. Materials and Methods: A PubMed and Medline search was performed of all English-language articles from 1960 using key words ?sepsis,?? ?urosepsis,?? ?obstruction,?? ?obstructive pyelonephritis,?? ?pyonephrosis,?? ?infection and hydronephrosis?? ?decompression,?? ?stent,?? ?nephrostomy,?? and ?management.?? The Cochrane database and National Institute for Clinical Effectiveness guidelines were searched using the terms ?sepsis,?? ?urosepsis,?? ?stent,?? ?nephrostomy,?? or ?obstruction.?? ...

2010-01-01

125

Viral suppression of multiple escape mutants by de novo CD8+ T cell responses in a human immunodeficiency virus-1 Infected elite suppressor  

UK PubMed Central (United Kingdom)

Elite suppressors or controllers (ES) are HIV-1 infected patients who maintain undetectable viral loads without treatment. While HLA-B*57-positive ES are usually infected with virus that is unmutated...Full Text Available

126

The Effect of Circumcision of HIV-Infected Men on Human Papillomavirus Infection in Female Partners: Analyses Using Data from a Randomized Trial in Rakai, Uganda  

UK PubMed Central (United Kingdom)

BackgroundMale circumcision (MC) reduces high-risk human papillomavirus (HR-HPV) in HIV-uninfected men and their female partners. We assessed whether MC of HIV-infected...Full Text Available

2011-08-01

127

The Changing Face of Pediatric Respiratory Tract Infections: How Human Metapneumovirus and Human Bocavirus Fit into the Overall Etiology of Respiratory Tract Infections in Young Children  

UK PubMed Central (United Kingdom)

Lower respiratory tract infections are one of the leading causes of morbidity and mortality in children worldwide. Recent technological advances in the field of molecular biology have allowed virologists...Full Text Available

2010-12-01

128

Staphylococcus aureus Enterotoxin D Is Secreted in Milk and Stimulates Specific Antibody Responses in Cows in the Course of Experimental Intramammary Infection  

UK PubMed Central (United Kingdom)

An enterotoxin D (SED)-producing strain of Staphylococcus aureus was used to infect one mammary gland of each of 17 lactating dairy cows. All glands became infected and shed bacteria...Full Text Available

2006-06-01

129

Malaria and other vector-borne infection surveillance in the U.S. Department of Defense Armed Forces Health Surveillance Center-Global Emerging Infections Surveillance program: review of 2009 accomplishments  

UK PubMed Central (United Kingdom)

Vector-borne infections (VBI) are defined as infectious diseases transmitted by the bite or mechanical transfer of arthropod vectors. They constitute a significant proportion of the global infectious...Full Text Available

130

Differential Changes in Heat Shock Protein-, Lipoarabinomannan-, and Purified Protein Derivative-Specific Immunoglobulin G1 and G2 Isotype Responses during Bovine Mycobacterium avium subsp. paratuberculosis Infection  

UK PubMed Central (United Kingdom)

Bovine paratuberculosis is caused by infection of young calves with Mycobacterium avium subsp. paratuberculosis. In some of the chronically infected cows the long asymptomatic...Full Text Available

2001-03-01

131

Both the Fas Ligand and Inducible Nitric Oxide Synthase Are Needed for Control of Parasite Replication within Lesions in Mice Infected with Leishmania major whereas the Contribution of Tumor Necrosis Factor Is Minimal  

UK PubMed Central (United Kingdom)

Following infection with the protozoan parasite Leishmania major, C57BL/6 mice develop a small lesion that heals spontaneously. Resistance to infection is associated with the development...Full Text Available

2003-09-01

132

Toll-like receptor 2 polymorphism and gram-positive bacterial infections after liver transplantation  

British Library Electronic Table of Contents (United Kingdom)

Abstract Toll-like receptor 2 (TLR2) is an immune sensor for gram-positive bacterial cell wall components. Single-nucleotide polymorphisms (SNPs) in the TLR2 gene that impair its function may, therefore, influence the risk and outcomes of gram-positive bacterial infections. In a cohort of 694 liver transplant recipients, we assessed the TLR2 SNP that is translated into an amino acid substitution of arginine for glutamine at position 753 (R753Q), and we found that its presence was associated with the clinical characteristics and outcomes of gram-positive bacterial infections. The proportions of patients with the TLR2 R753Q SNP did not significantly differ between those with gram-positive bacterial infections and those without gram-positive bacterial infections (9.6% versus 9.6%, P = 0.999)....

2011-01-01

133

The genetics and evolution of obligate reproductive parasitism in Trichogramma pretiosum infected with parthenogenesis-inducing Wolbachia  

British Library Electronic Table of Contents (United Kingdom)

Parthenogenesis-inducing (PI) Wolbachia belong to a class of intracellular symbionts that distort the offspring sex ratio of their hosts toward a female bias. In many PI Wolbachia-infected species sex ratio distortion has reached its ultimate expression-fixation of infection and all-female populations. This is only possible with thelytokous PI symbionts as they provide an alternative form of reproduction and remove the requirement for males and sexual reproduction. Many populations fixed for PI Wolbachia infection have lost the ability to reproduce sexually, even when cured of the infection. We examine one such population in the species Trichogramma pretiosum. Through a series of backcrossing experiments with an uninfected Trichogramma pretiosum population we were able to show that the gen...

2011-01-01

134

PREVENTION OF INFECTION IN PATIENTS WITH CHRONIC KIDNEY DISEASE PART III: SURVEILLANCE AND AUDITING IN A RENAL CARE ENVIRONMENT  

British Library Electronic Table of Contents (United Kingdom)

Summary This third paper, in a three-part CE series on the preventions of infection in patients with chronic kidney disease, focuses on surveillance and auditing of healthcare-associated infections within the renal care environment. The last decade has seen an increased awareness of the threat to patient safety from healthcare-associated infection (HCAI) and the emergence of multi-drug resistance organisms. Effective HCAI prevention strategies include adequate governance structures, access to expert advice, adherence to standard and transmission-based precautions, minimising the use of invasive medical devices, and surveillance. Surveillance data can be collected using outcome (e.g. infection) and/or process (e.g. hand hygiene compliance audit) measures. Establishing a surveillance program...

2011-01-01

135

Mannose-binding lectin codon 54 gene polymorphism in relation to risk of nosocomial invasive fungal infection in preterm neonates in the neonatal intensive care unit  

British Library Electronic Table of Contents (United Kingdom)

Objective. Preterm neonates are susceptible to infection due to a combination of sub-optimal immunity and increased exposure to invasive organisms. Invasive fungal infections are associated with significant morbidity and mortality among preterm infants cared for in the neonatal intensive care unit (NICU). Mannose-binding lectin (MBL) is a component of the innate immune system, which may be especially important in the neonatal setting. The objective of this study was to investigate the presence of any association between MBL gene polymorphism and nosocomial invasive fungal infection in preterm neonates. Methods. Codon 54 (B allele) polymorphism in exon 1 of the MBL gene was investigated in 31 patients diagnosed as nosocomial invasive fungal infection and 30 control preterm neonates. Results...

2011-01-01

136

Herpesvirus saimiri infection of rhesus macaques: A model for acute rhadinovirus-induced t-cell transformation and oncogenesis  

British Library Electronic Table of Contents (United Kingdom)

Abstract Herpesvirus saimiri (HVS) causes acute lymphoma and leukemia upon experimental infection of various monkey species. HVS strain C488 is also capable of transforming human T-lymphocytes to stable growth in culture. The most susceptible species for oncogenesis are New World primates, in particular the cottontop tamarin (Saguinus oedipus). However, Old World monkeys such as macaques are the most used animal model for the close-to-human situation. The limited data on HVS infection in Old World monkeys prompted us to investigate susceptibility to infection and disease induction by HVS in macaques. After having established that rhesus macaques can be infected productively, and that rhesus T-cells can be transformed in vivo by HVS, we observed induction of lymphoma in all inoculated anima...

2011-01-01

137

Experimental bovine trypanosomiasis. Changes in serum immunoglobulins, complement and complement components in infected animals.  

Science.gov (United States)

In three calves experimentally infected with Trypanosoma congolense the amounts of IgG1 and IgG2 were little changed and similar to those of normal animals. IgM increased in amount early in the infection and the amount of the increase appeared related to the parasite burden. The amounts of IgA and IgE were both much decreased and this also appeared related to the numbers of parasites in the blood. There was a decrease in the amounts of total haemolytic complement and complement components C1, C1q and C3 in the infected calves. Furthermore the amounts of properdin fluctuated with the cyclical changes in numbers of T. congolense parasites in the individual calves. No significant change in the amount of C8 was observed. It is considered that activation of both the alternative and the classical complement pathways occurs in trypanosome infected animals but that neither pathway goes to its terminal stages.

1978-11-01

138

Anti-Infection Dip Suggestions for the Coloplast Titan Inflatable Penile Prosthesis in the Era of the Infection Retardant Coated Implant  

British Library Electronic Table of Contents (United Kingdom)

Abstract Introduction.- Infection is the worst complication seen with inflatable penile prosthesis (IPP). Both the American Medical Systems (AMS) and Coloplast IPP have infection retardant coatings. AMS is coated at the factory with rifampicin and minocycline (InhibiZone). The Coloplast IPP has a hydrophilic coating covalently bonded to its components that will absorb any aqueous solution before implantation and provides increased surface lubricity to decrease bacterial adherence. Aim.- We tested several antibiotic dips comparing zones of inhibition (ZOI) against five commonly infecting bacteria with coated Coloplast implants. Results were compared with those ZOI created with strips of an AMS IPP precoated with InhibiZone. Methods.- Pieces of sterile Coloplast Titan IPP were dipped in (i) ...

2011-01-01

139

Infected nonunion of the long bones.  

Science.gov (United States)

BACKGROUND: Although definitions vary, infected nonunion has been defined as a state of failure of union and persistence of infection at the fracture site for 6 to 8 months.>). Infected nonunions of the supracondylar region of the femur are uncommon and are mostly due to a severe open fracture with extensive comminution and segmental bone loss or after internal fixation of a comminuted closed fracture. Associated factors include exposed bone devoid of vascularized periosteal coverage for more than 6 weeks, purulent discharge, a positive bacteriological culture from the depth of the wound, and histologic evidence of necrotic bone containing empty lacunae. Soft-tissue loss with multiple sinuses, osteomyelitis, osteopenia, complex deformities with limb-length inequality, stiffness of the adjacent joint, polybacterial multidrug-resistant infection, and smoking all complicate treatment and recovery. ...

2007-08-01

140

The Swedish dilemma - Nuclear energy v. the environment  

Energy Technology Data Exchange (ETDEWEB)

A phaseout of nuclear power in Sweden is supposed to be accomplished by year 2010. This study is an economic analysis of the questions that are parts of the nuclear dilemma. Even though the economic questions are in focus, the important environmental, health and safety questions are also treated. The basic argument is that Sweden should choose an energy system that allows its citizens to maximize their consumption in a long-term perspective. Consumption is here given a meaning that includes elements outside the market, such as environmental, health and safety aspects valued in a reasonable way. Considerations must also be given to international aspects like global environment, a free and open system of trade and the value of a stable set of rules and proprietary rights. The study compares the economic pros and cons of different energy systems within this general frame. A detailed model of the Swedish energy and power sectors was developed for ...

1995-11-01

141

Public involvement in the siting of contentious facilities; Lessons from the radioactive waste repository siting programmes in Canada and the United States, with special reference to the Swedish repository siting process  

Energy Technology Data Exchange (ETDEWEB)

This report describes the conclusion of a two-part programme, begun in 1994 with the overall aim of assisting in the development of an acceptable public participation strategy for use in Sweden for the siting of contentious facilities, with particular reference to the ongoing siting programme for a deep repository for spent nuclear fuel. The first part of the work programme, a global review of siting practice, was reported as SSI Rapport 94-15, in November 1994. This recommended further detailed studies of at least two individual programmes, which have now been carried out in Canada and the United States, and are reported on here. They involved face to face meetings with many of the main stake holders in the two programmes and enabled valuable insight to be gained into the potential problems associated with increased public participation, as well as identifying good practice where it exists. The lessons learned have then been applied to the evolving repository ...

1997-08-01

142

(Packaging regulations for chemical explosives)  

Energy Technology Data Exchange (ETDEWEB)

The purpose of the trip was to visit Nobel Chemicals in Sweden and to confer with the Department of Transportation personnel in Sweden and in England on the technical and regulatory problems in the bulk shipping of the high explosives RDX and HMX. It is customary in the United States (US) to add isopropyl alcohol to the bulk shipment of water-wet high explosives RDX and HMX. The explosives are packed in cloth bags which are placed in plastic-lined fiber drums. The addition of alcohol presumably prevents mildewing of cloth bags and freezing of the wet explosives in cold weather. In Europe, however, these explosives are shipped in polyethylene-lined fiber drums with not less than 15% water only, even in cold weather. Water-wet frozen explosives have not proved to be any more sensitive than its unfrozen counterpart and no mildew problem has been encountered. It looks promising that the US Department of Transportation regulations can be changed to ...

1988-02-17

143

Comparative analysis of budded virus infectivity of Bombyx mandarina and B. mori nucleopolyhedroviruses.  

Science.gov (United States)

Bombyx mandarina nucleopolyhedrovirus (BomaNPV) is a variant of Bombyx mori nucleopolyhedrovirus (BmNPV). BomaNPV S1 strain has been reported to be significantly less virulent than the BmNPV T3 strain via the oral infection route in B. mori larvae, but other features of S1 including budded virus (BV) infectivity and virus propagation in cultured cells are still unknown. In this study, we compared BV infectivity of S1 and T3 in B. mori larvae and cultured cells. Larval bioassays by intrahemocoelic BV injection revealed that the median lethal dose of S1's BV was approximately three times lower than that of T3. In addition, S1 produced more BVs and occlusion bodies (OBs) in the hemolymph of B. mori larvae compared with T3. Furthermore, we observed that the locomotion was enhanced earlier and the median lethal time was shorter in S1-infected larvae compared with those in T3-infected ...

2011-05-22

144

Uncertainties of radionuclide migration parameter values obtained from in-situ tracer experiments  

International Nuclear Information System (INIS)

One of the key issues in safety assessment of high-level nuclear waste disposal is evaluating the effects of uncertainty inherent in radionuclide migration parameter values. In this paper, radionuclide transport parameter values and error variances (uncertainties) from in-situ tracer experiments, carried out in a single fracture at the Aespoe Hard Rock Laboratory (HRL) in Sweden, are identified by solving the inverse problem in a framework of the maximum likelihood theory. From the results, it is found that the parameter value uncertainty caused by a conceptual model of radionuclide migration is greater than that caused by a fluctuation in the observed breakthrough curve data. (author)

2005-10-03

145

Report of study group 7.1: natural gas in competition with electric power in industrial applications  

Energy Technology Data Exchange (ETDEWEB)

This report consists of three sections. The first section is a brief general overview of all the issues that impact the competition between natural gas and electricity in industrial applications. The second section of this report focus on the all the marketing issues and provides detail analysis of the status of these issues in Europe, Japan and United States. The third section of this report is a detail review of the current status of the competition between gas technologies and electro-technologies, it also make recommendation for developing new gas technologies. The fourth section is a contribution from M. Pettersson and S. Stenstroem, Sweden, on infrared dryers. (authors)

2000-07-01

146

Radon measurements in dwellings using activated charcoal  

Energy Technology Data Exchange (ETDEWEB)

In Sweden there is a demand for a method of measuring radon in dwellings with high accuracy and at a low cost. A method of determining radon concentration (Bq.m/sup -3/) in dwellings has been developed at the Swedish National Testing Institute. A plastic canister containing activated charcoal has been tested in a radon chamber (volume 20 m/sup 3/) to determine the effects of relative humidity, temperature and exposure time. The activated charcoal in the canister adsorbs radon from the air surrounding the canister. The radon concentration is determined by counting the gamma rays from the decay of radon and daughters. The theory and preliminary results from calibrations and field measurements are reported.

1984-01-01

147

Organisation of care for Swedish patients with an implantable cardioverter defibrillator, a national survey  

British Library Electronic Table of Contents (United Kingdom)

Aim.- To describe the clinical aspects of implantable cardioverter defibrillators care in Sweden with focus on organisation, the role and education of nurses, patient information and education and areas in need of improvement. Background.- Implantable cardioverter defibrillators implantations have developed rapidly in recent years and are now an established arrhythmia treatment. The expanding indication for implantable cardioverter defibrillators implantation demands new competencies and resources in the implantable cardioverter defibrillators team members. Methods.- Participants were recruited among physicians and nurses in all of the hospitals implanting implantable cardioverter defibrillators (n-=-16). Data were collected by a questionnaire. Additionally, all written educational materia...

2011-01-01

148

Dextranomer/hyaluronic acid copolymer (Deflux) implants mimicking distal ureteral calculi on CT  

Energy Technology Data Exchange (ETDEWEB)

Periureteral or subtrigonal injection of dextranomer/hyaluronic acid (Dx/HA) copolymer (Deflux, Q-Med, Uppsala, Sweden) is an increasingly common endoscopic treatment for vesicoureteral reflux. We report a confusing radiographic finding of bilateral calcified Dx/HA injections initially thought to represent bilateral distal ureteral stones in a boy who presented with intermittent periumbilical pain. Urologists, radiologists, and emergency room physicians should be aware of the potential for calcification of ureteral implants of Dx/HA, and of the potentially confusing radiographic images that may result. (orig.)

2008-01-15

149

Between academization and good craftmanship. The physiotherapists' ambition to professionalize in the light of the conductive education challenge  

British Library Electronic Table of Contents (United Kingdom)

During the 1990s, a debate took place in Sweden concerning Conductive Education. Proponents of this method focused their critique on the role and methods of physiotherapists but this profession was not active in the debate. Instead, the medical profession came out as defenders of habilitation services and methods. Departing from sociology of the professions, our objective in this article is to analyze the physiotherapists' silence in relation to the profession's position and its relation to the medical profession. The analysis is based on data from interviews with members of habilitation teams and other key persons, and on documents. The relative silence of physiotherapists is found to be related to both interprofessional factors (the subordination under the medical profession paired with ...

2011-01-01

150

Emissions to air in Sweden: sulphur dioxide, nitrogen oxides, carbon dioxide, methane, nitrous oxide, carbon monoxide and volatile organic compounds, 1999  

International Nuclear Information System (INIS)

The method for calculating emissions to air has been revised, which has led to adjustments. Because of this, emissions in 1999 cannot yet be compared with previous years. Emissions in 1990 - 1998 are being recalculated now using the new method and are expected to be ready during 2001. Emissions to air of carbon dioxide (CO_2) in Sweden was 56.58 million tonnes in 1999, not including emissions from biofuels and international bunkers. The major sources of CO_2 emissions are the combustion of fossil fuels and the use of fuels for mobile sources. Total emissions to air of sulphur dioxide (SO_2) and nitrogen oxides (NO_x, counted as NO_2) in Sweden was 66 000 and 263 000 tonnes respectively in 1999. International bunkers are not included. The major source of SO_2 emissions is combustion of fossil fuels. Road traffic is the major source of NO_x emissions. Emissions to air of methane (CH_4), nitrous oxide (N_2O), carbon monoxide (CO) and volatile ...

2000-11-01

151

Viruses and thyroiditis: an update  

UK PubMed Central (United Kingdom)

Viral infections are frequently cited as a major environmental factor involved in subacute thyroiditis and autoimmune thyroid diseases This review examines the data related to the role of viruses in...Full Text Available

152

Trimethoprim sulphamethoxazole in neonatal Flavobacterium meningosepticum infection.  

UK PubMed Central (United Kingdom)

During an outbreak of Flavobacterium meningosepticum septicaemia in a neonatal intensive care unit 9 infants were treated with intravenous trimethoprim sulphamethoxazole. Bacteriological cure was achieved...Full Text Available

1984-06-01

153

Tobacco-induced alterations to Porphyromonas gingivalis-host interactions  

UK PubMed Central (United Kingdom)

SUMMARYSmokers are more susceptible than non-smokers to persistent infection by Porphyromonas gingivalis, a causative agent of periodontitis. Patients who smoke...Full Text Available

2009-05-01

154

Rifampin Combination Therapy for Nonmycobacterial Infections  

UK PubMed Central (United Kingdom)

Summary: The increasing emergence of antimicrobial-resistant organisms, especially methicillin-resistant Staphylococcus aureus (MRSA), has resulted in the increased...Full Text Available

2010-01-01

155

Reduction in incidence of deep sternal wound infections: Random or real?  

British Library Electronic Table of Contents (United Kingdom)

Objective Comorbidities predisposing cardiac surgical patients toward deep sternal wound infection, such as diabetes and obesity, are rising in the United States. Longitudinal analysis of risk factors, morbidity, and mortality was performed to assessed effects of these health trends on deep sternal wound infection rates. Methods In this retrospective analysis of all median sternotomies performed at a single institution from 1991 through 2006, demographic and surgical characteristics were identified from a prospective database. The cohort was separated into periods from 1992 through 2001 and 2002 through 2006 to identify longitudinal trends in risk factors for deep sternal wound infection. Univariate and matched multivariable analyses were performed. Results Overall, study population had in...

2010-01-01

156

Recurrent corneal ulceration in presence of synthetic microfibrils  

UK PubMed Central (United Kingdom)

Recurrence of microbial keratitis in the presence of protozoal infection is very rare and infrequently reported unless predisposing factors are present. The association of recurrent microbial keratitis...Full Text Available

2011-01-01

157

Probiotic-Induced Priming of Innate Immunity to Protect Against Rotaviral Infection  

British Library Electronic Table of Contents (United Kingdom)

Understanding of probiotic-induced regulatory gene expression and networking is critical to further explore their roles in controlling infection. Transcriptional profile of selected innate immune genes in primary bovine intestinal epithelial cells was assessed over a time course of incubation with the probiotic Lactobacillus plantarum 299v. Based on gene expression results, a time point was chosen to prime epithelial cells with the probiotic prior to infection with rotavirus. Plaque assays and genomic analysis provided the basis for establishing the efficacy of probiotics in preventing a rotaviral infection. Plaque assays revealed that the probiotic is capable of decreasing (at least by 100-fold) the levels of live virus when the cells were primed with the probiotic. Results from gene expr...

2010-01-01

158

Prevalence-Dependent Costs of Parasite Virulence  

UK PubMed Central (United Kingdom)

Costs of parasitism are commonly measured by comparing the performance of infected groups of individuals to that of uninfected control groups. This measure potentially underestimates the cost of parasitism...Full Text Available

2005-08-01

159

Phylogenomic analyses of malaria parasites and evolution of their exported proteins  

UK PubMed Central (United Kingdom)

BackgroundPlasmodium falciparum is the most malignant agent of human malaria. It belongs to the taxon Laverania, which includes other ape-infecting Plasmodium...Full Text Available

160

Photorhabdus luminescens genes induced upon insect infection  

UK PubMed Central (United Kingdom)

BackgroundPhotorhabdus luminescens is a Gram-negative luminescent enterobacterium and a symbiote to soil nematodes belonging to the species Heterorhabditis...Full Text Available

161

PHENOTYPIC MODIFICATION OF ROACH (RUTILUS RUTILUS L.) INFECTED WITH LIGULA INTESTINALIS L. (CESTODA: PSEUDOPHYLLIDEA)  

Science.gov (United States)

... growth hormone-like factor from plerocercoids of the tapeworm Spirometra mansonoides is a multifunctional protein. In Parasites and pathogens: ... ...

162

Non-toxigenic Clostridium sordellii: Clinical and microbiological features of a case of cholangitis-associated bacteremia  

British Library Electronic Table of Contents (United Kingdom)

Toxigenic Clostridium sordellii strains are increasingly recognized to cause highly lethal infections in humans that are typified by a toxic shock syndrome (TSS). Two glucosylating toxins, lethal toxin (TcsL) and hemorrhagic toxin (TcsH) are believed to be important in the pathogenesis of TSS. While non-toxigenic strains of C. sordellii demonstrate reduced cytotoxicity in vitro and lower virulence in animal models of infection, there are few data regarding their behavior in humans. Here we report a non-TSS C. sordellii infection in the context of a polymicrobial bacterial cholangitis. The C. sordellii strain associated with this infection did not carry either the TcsL-encoding tcsL gene or the tcsH gene for TcsH. In addition, the strain was neither cytotoxic in vitro nor lethal in a murine...

2011-01-01

163

Microbiologic Evaluation of Patients from Missouri with Erythema Migrans  

UK PubMed Central (United Kingdom)

BackgroundBorrelia lonestari infects Amblyomma americanum, the tick species that is the most common cause of tick bites in southeast...Full Text Available

2005-02-01

164

Isoprinosine augmentation of phytohemagglutinin-induced lymphocyte proliferation.  

UK PubMed Central (United Kingdom)

The need for agents designed to modify immune response in the treatment of patients with viral infection, immunodeficiency, or cancer prompted the present study on the mechanisms of action of isoprinosine,...Full Text Available

1976-02-01

165

Intestinal parasitic infections and urbanization.  

UK PubMed Central (United Kingdom)

About a third of the population in the cities of developing countries live in slums and shanty towns. By the year 2000 it is estimated that this number will grow to 2200 million, and by 2025 about 57%...Full Text Available

1993-01-01

166

In Vitro Toxicity of Silver Nanoparticles in Human Lung ...  

Science.gov (United States)

... The MTT assay indicates cell viability through a yellow to purple ... besiegers were said to have catapulted plague infected corpses into the city of ...

2009-03-01

167

INJECTABLE IN SITU CROSS-LINKING HYDROGELS FOR LOCAL ANTIFUNGAL THERAPY  

UK PubMed Central (United Kingdom)

Invasive fungal infections can be devastating, particularly in immunocompromised patients, and difficult to treat with systemic drugs. Furthermore, systemic administration of those medications...Full Text Available

2010-02-01

168

Epidemiology, prevention and control of legionellosis: memorandum from a WHO meeting.  

UK PubMed Central (United Kingdom)

This Memorandum describes the following aspects of legionellosis: clinical presentations of legionella infection, general epidemiology (including nosocomial outbreaks and travel-associated legionnaires'...Full Text Available

1990-01-01

169

Current problems of perinatal Chlamydia trachomatis infections  

UK PubMed Central (United Kingdom)

Chlamydia trachomatis has been recognized as a pathogen of trachoma, nongonococcal urethritis, salpingitis, endocervicitis, pelvic inflammatory disease, inclusion conjunctivitis of...Full Text Available

170

Cowper's syringocele: an analysis of 15 consecutive cases.  

UK PubMed Central (United Kingdom)

Cystic dilatation of Cowper's gland ducts (Cowper's syringocele) is uncommon in children and is frequently asymptomatic, but it may cause urinary infection, haematuria, dysuria, and obstructive voiding...Full Text Available

1996-07-01

171

Clinical, virological and immunological responses in Danish HIV patients receiving raltegravir as part of a salvage regimen  

DEFF Research Database (Denmark)

Raltegravir is the first integrase inhibitor approved for treatment of HIV-infected patients harboring multiresistant viruses.

2010-01-01

172

Clinical significance of coagulase-negative staphylococci.  

UK PubMed Central (United Kingdom)

Although coagulase-negative staphylococci (C-NS) have been implicated in certain human infections, they are generally regarded as contaminants, and their clinical significance is questioned. To assess...Full Text Available

1982-08-01

173

Bacterial vaginosis and other asymptomatic vaginal infections in pregnancy.  

Science.gov (United States)

Preterm birth is a common cause of neonatal morbidity and mortality. Many asymptomatic genital infections have been associated with preterm birth, but attempts to determine a causal relationship between specific infections and preterm birth have been disappointing. Treatment trials of specific infections have generally failed to show a positive effect, and in some trials have shown a deleterious effect. Although there is a strong association between the presence of bacterial vaginosis and Trichomonas vaginalis in pregnancy and preterm birth, randomized treatment trials have failed to show a benefit of treatment of these organisms. Treatment of asymptomatic bacterial vaginosis or T. vaginalis to prevent preterm birth is not warranted. PMID:12112946

2001-08-01

174

Application of chloropicrin to Douglas-fir stumps to control laminated ...  

Science.gov (United States)

Sep 1, 2011 ... Title: Application of chloropicrin to Douglas-fir stumps to control laminated root rot does not affect infection or growth of regeneration 16 growing ...

176

A prospective randomised open label study to evaluate the potential of a new silver alginate/carboxymethylcellulose antimicrobial wound dressing to promote wound healing  

British Library Electronic Table of Contents (United Kingdom)

The aim of this study was to observe both the clinical signs and symptoms of wounds at risk of infection, that is critically colonised (biofilm infected) and antimicrobial-performance of an ionic silver alginate/carboxymethylcellulose (SACMC) dressing, in comparison with a non silver calcium alginate fibre (AF) dressing, on chronic venous leg and pressure ulcers. Thirty-six patients with venous or pressure ulcers, considered clinically to be critically colonised (biofilm infected), were randomly chosen to receive either an SACMC dressing or a non silver calcium AF dressing. The efficacy of each wound dressing was evaluated over a 4-week period. The primary study endpoints were prevention of infection and progression to wound healing. The SACMC group showed a statistically significant (P = ...

2010-01-01

177

A Novel Multi-Antigen Virally Vectored Vaccine against Mycobacterium avium Subspecies paratuberculosis  

UK PubMed Central (United Kingdom)

BackgroundMycobacterium avium subspecies paratuberculosis causes systemic infection and chronic intestinal inflammation in many species including...Full Text Available

178

The bovine immune response to Brucella abortus I. A water soluble antigen precipitated by sera of some naturally infected cattle.  

UK PubMed Central (United Kingdom)

Selected sera from cattle naturally infected with Brucella abortus precipitate water soluble antigens extracted by sonication from B. abortus. One of these antigens resembles antigen E (Baughn and Freeman)...Full Text Available

1977-04-01

179

Syncope as a probable side effect to combination antiretroviral therapy initiated during primary HIV-1 infection  

DEFF Research Database (Denmark)

A previously healthy young man experienced several episodes of syncope while being treated with tenofovir, emtricitabine and nevirapine initiated during primary HIV-1 infection. Symptoms disappeared after discontinuation of antiretroviral therapy and we suggest that syncope may be a side effect to one of the three antiretroviral drugs that has not been described previously.

2008-01-01

180

Ribose metabolism and nucleic acid synthesis in normal and glucose-6-phosphate dehydrogenase-deficient human erythrocytes infected with Plasmodium falciparum.  

UK PubMed Central (United Kingdom)

The metabolism of pentose-phosphate was investigated in Plasmodium falciparum-infected normal and glucose-6-phosphate dehydrogenase (G6PD)-deficient human red blood cells in vitro. 5'-Phosphoribosyl-1-pyrophosphate...Full Text Available

1986-04-01

181

Quantitation of transcribing native simian virus 40 minichromosomes extracted from CV1 cells late in infection.  

UK PubMed Central (United Kingdom)

Simian virus 40 transcriptional complexes could be extracted from CV1 cells late in infection and separated from the bulk of inactive viral chromatin. Sucrose gradient sedimentation, cesium sulfate...Full Text Available

1981-04-01

182

Primitive hematopoietic cells resist HIV-1 infection via p21Waf1/Cip1/Sdi1  

UK PubMed Central (United Kingdom)

Hematopoietic stem cells are resistant to HIV-1 infection. Here, we report a novel mechanism by which the cyclin-dependent kinase inhibitor (CKI) p21Waf1/Cip1/Sdi1 (p21), a known regulator...Full Text Available

2007-02-01

183

Practical approach to the loss of smell  

Energy Technology Data Exchange (ETDEWEB)

Loss of the sense of smell can be easily confirmed in any physician's office by having the patient try to identify various odors. The etiology of anosmia can be extremely varied, including nasopharyngeal disorders such as rhinitis and tumors; neurologic conditions such as head trauma, neoplasms, vascular lesions and infections of the central nervous system; viral infections; familial and congenital disorders; drugs; industrial exposure; endocrine diseases, and several other disorders. The prognosis of anosmia is guarded, and its treatment depends on the etiology.

1982-09-01

184

Lytic HSV-1 infection induces the multifunctional transcription factor Early Growth Response-1 (EGR-1) in rabbit corneal cells  

UK PubMed Central (United Kingdom)

BackgroundHerpes simplex virus type-1 (HSV-1) infections can cause a number of diseases ranging from simple cold sores to dangerous keratitis and lethal encephalitis. The interaction...Full Text Available

185

Live Brucella spp. fail to induce tumor necrosis factor alpha excretion upon infection of U937-derived phagocytes.  

UK PubMed Central (United Kingdom)

Tumor necrosis factor alpha (TNF-alpha) plays a central role in activation of first-line defenses of a host against foreign organisms. To determine whether Brucella infection modulated TNF-alpha production,...Full Text Available

1994-12-01

186

Intestinal helminths infection of rats (Ratus norvegicus) in the Belgrade area (Serbia): the effect of sex, age and habitat.  

Science.gov (United States)

SUMMARY: Gastrointestinal helminths of Norway rat (Rattus norvegicus) from the Belgrade area were studied as a part of a wider ecological research of rats in Serbia (data on the distribution, population ecology, economic and epizoothiological-epidemiological importance, and density control). Rats were captured from May 2005 to July 2009 at both urban and suburban-rural sites. Of a total of 302 trapped rats 48% were males and 52% females, with 36.5% and 38.8% of juvenile-subadult individuals, per sex respectively. Intestinal helminth infection was noted in 68.5% of rats, with a higher prevalence in male hosts and in adult individuals. Higher numbers of infected juveniles-subadults were noted in suburban-rural habitats, while an opposite tendency was noted in adult rats. Seven helminth species were recovered, of which five were nematode (Heterakis spumosa, Nippostrongylus brasiliensis, Capillaria sp., Trichuris muns and Syphacia muris) and two ...

2011-05-01

187

Interaction of ?V?3 and ?V?6 Integrins with Human Parechovirus 1?  

UK PubMed Central (United Kingdom)

Human parechovirus (HPEV) infections are very common in early childhood and can be severe in neonates. It has been shown that integrins are important for cellular infectivity of HPEV1 through experiments...Full Text Available

2010-09-01

188

Infection disclosure in the injecting dyads of Hungarian and Lithuanian injecting drug users who self-reported being infected with hepatitis C virus or human immunodeficiency virus.  

Science.gov (United States)

The aim of this study was to assess the prevalence and correlates of disclosure to network members of being hepatitis C virus (HCV)- or human immunodeficiency virus (HIV)-infected among injecting dyads of infected injection drug users (IDUs) in Budapest, Hungary and Vilnius, Lithuania,. Multivariate generalized estimating equations (GEE) were used to assess associations. Very strong infection disclosure norms exist in Hungary, and HCV disclosure was associated with using drugs and having sex within the dyad. Non-ethnic Russian IDUs in Lithuania were more likely to disclose HCV infection to non-Roma, emotionally close and HCV-infected network members, and to those with whom they shared cookers, filters, drug solutions or rinse water or got used syringes from, and if they had fewer non-IDU or IDU network members. Ethnic Russian Lithuanian IDUs were more likely to disclose HCV if they ...

2010-09-15

189

Indirect hemagglutination employing enterobacterial common antigen and Yersinia somatic antigen: a technique to differentiate brucellosis from infections involving cross-reacting Yersinia enterocolitica.  

UK PubMed Central (United Kingdom)

The existence of enterobacterial common antigen in Yersinia enterocolitica and its absence in Brucella abortus were utilized in an attempt to provide a method to distinguish Brucella infections from...Full Text Available

1980-02-01

190

Hypothyroidism in Noninterferon Treated-HCV Infected Individuals Is Associated with Abnormalities in the Regulation of Th17 Cells  

UK PubMed Central (United Kingdom)

HCV-Ag-specific TH17 cells secrete IL17, a cytokine involved in autoimmune diseases and regulated by IL10 and TGF-b. 5–12% of patients with chronic HCV infection have hypothyroidism. We evaluated...Full Text Available

2010-01-01

191

Evolutionary Constraints Acting on DDX3X Protein Potentially Interferes with Rev-Mediated Nuclear Export of HIV-1 RNA  

UK PubMed Central (United Kingdom)

Differential host-pathogen interactions direct viral replication in infected cells. In HIV-1 infected cells, nuclear export of viral RNA transcripts into cellular cytoplasm is governed by interaction...Full Text Available

192

Evolution of Hepatitis B Virus in a Chronic HBV-Infected Patient over 2 Years  

UK PubMed Central (United Kingdom)

Mutations in full-length HBV isolates obtained from a chronic HBV-infected patient were evaluated at three time points: 1 day, 6 months, and 31 months. While 5 nucleotides variation, and an 18 bp...Full Text Available

2011-01-01

193

Dissecting toxin immunity in virus-infected killer yeast uncovers an intrinsic strategy of self-protection  

UK PubMed Central (United Kingdom)

Toxin-secreting “killer” yeasts were initially identified >40 years ago in Saccharomyces cerevisiae strains infected with a double-stranded RNA “killer”...Full Text Available

2006-03-07

194

Detecting Sugarcane yellow leaf virus infection in asymptomatic leaves with hyperspectral remote sensing and associated leaf pigment analysis  

Science.gov (United States)

Sugarcane yellow leaf caused by Sugarcane yellow leaf virus (ScYLV) does not produce visual symptoms in most susceptible plants until late in the growing season. An experiment was conducted to determine if leaf reflectance and pigment analysis could be used to determine ScYLV infection prior to sym...

195

Dengue Plaque Reduction Neutralization Test (PRNT) in Primary and Secondary Dengue Virus Infections: How Alterations in Assay Conditions Impact Performance  

UK PubMed Central (United Kingdom)

Dengue virus (DENV) infection is a worsening global health problem. The plaque reduction neutralization test (PRNT) is currently considered to be the “gold standard” to characterize...Full Text Available

2009-11-01

196

Cerebral sparganosis. Case report.  

Science.gov (United States)

The tapeworm Spirometra mansonoides infects man worldwide, particularly in Asian countries. Rarely, the central nervous system is involved; such a case is presented here. In the total of 12 reported cases, including the case described, the worm presented clinically as a mass suspicious for neoplasm or chronic abscess cavity. Surgical removal was invariably curative in each case. Although infrequent, the possibility of tapeworm infection should be entertained in the evaluation of intracranial masses in patients who have visited exotic locales. PMID:2191089

1990-07-01

197

Association between Handling of Pet Treats and Infection with Salmonella enterica Serotype Newport Expressing the AmpC ?-Lactamase, CMY-2  

UK PubMed Central (United Kingdom)

Resistance to the extended-spectrum cephalosporins can occur in Salmonella species via the production of extended-spectrum and AmpC β-lactamases. We describe human infections...Full Text Available

2003-10-01

198

??+ T-Lymphocyte Cytotoxicity against Envelope-Expressing Target Cells Is Unique to the Alymphocytic State of Bovine Leukemia Virus Infection in the Natural Host  

UK PubMed Central (United Kingdom)

Bovine leukemia virus (BLV) is a complex B-lymphotrophic retrovirus of cattle and the causative agent of enzootic bovine leukosis. Serum antibody in infected animals does not correlate with protection...Full Text Available

2000-09-01

199

Position of nuclear-medical techniques for evaluation of loosened total hip endroprostheses  

Energy Technology Data Exchange (ETDEWEB)

For diagnosis of loosening or infection after implantation of a single-side or double-side total hip endoprosthesis 59 patients being in pain were investigated by a combination of bone scan (Technetium-99m DPD) and leucocyte scan (Indium-111 labelled leucocytes). The correlation between clinical results and scintigraphic findings revealed: bone scintigraphy detects loosening of prostheses with 95% sensitivity (45/47); bone scintigraphy excludes an instable prosthesis with 89% specificity (3/27). 45% of the loosened prostheses revealed an infection (21/47): leucocyte scintigraphy could detect 17 correct positive. Three leucocyte scans of 53 prostheses without clinical signs of infection were false positive. Therefore, leucocyte scintigraphy had a sensitivity of 91% and a specificity of 94% for detecting infection. Bone scintigraphy can detect loosening of prostheses with 93% accuracy, Indium-111 labelled ...

1985-10-01

200

In vivo hypermutation of xenotropic murine leukemia virus-related virus DNA in peripheral blood mononuclear cells of rhesus macaque by APOBEC3 proteins.  

Science.gov (United States)

The gammaretrovirus, xenotropic murine leukemia virus-related virus (XMRV), replicates to high titers in some human cell lines and is able to infect non-human primates. To determine whether APOBEC3 (A3) proteins restrict XMRV infections in a non-human primate model, we sequenced proviral DNA from peripheral blood mononuclear cells of XMRV-infected rhesus macaques. Hypermutation characteristic of A3DE, A3F and A3G activities was observed in the XMRV proviral sequences in vivo. Furthermore, expression of rhesus A3DE, A3F, or A3G in human cells inhibited XMRV infection and caused hypermutation of XMRV DNA. These studies show that some rhesus A3 isoforms are highly effective against XMRV in the blood of a non-human primate model of infection and in cultured human cells. PMID:21982221

2011-10-01

201

Human T-cell lymphotropic virus type III infection of the central nervous system: a preliminary in situ analysis  

Energy Technology Data Exchange (ETDEWEB)

Patients with acquired immunodeficiency syndrome (AIDS) are subject to a spectrum of central nervous system (CNS) disorders. Recent evidence implicates the human T-cell lymphotropic virus type III (HTLV-III) in the pathogenesis of some of these illnesses, although the cells infected by the virus have yet to be identified. Using in situ hybridization, the authors examined brain tissue from two patients with AIDS encephalopathy for the presence of HTLV-III RNA. In both cases, viral RNA was detected and concentrated in, though not limited to, the white matter. The CNS cells most frequently infected included macrophages, pleomorphic microglia, and multinucleated giant cells. Less frequently, cells morphologically consistent with astrocytes, oligodendroglia, and rarely neurons were also infected. The findings strengthen the association of HTLV-III with the pathogenesis of AIDS encephalopathy. In situ hybridization can be applied ...

1986-11-07

202

A prospective randomised open label study to evaluate the potential of a new silver alginate/carboxymethylcellulose antimicrobial wound dressing to promote wound healing.  

Science.gov (United States)

The aim of this study was to observe both the clinical signs and symptoms of wounds at risk of infection, that is critically colonised (biofilm infected) and antimicrobial-performance of an ionic silver alginate/carboxymethylcellulose (SACMC) dressing, in comparison with a non silver calcium alginate fibre (AF) dressing, on chronic venous leg and pressure ulcers. Thirty-six patients with venous or pressure ulcers, considered clinically to be critically colonised (biofilm infected), were randomly chosen to receive either an SACMC dressing or a non silver calcium AF dressing. The efficacy of each wound dressing was evaluated over a 4-week period. The primary study endpoints were prevention of infection and progression to wound healing. The SACMC group showed a statistically significant (P = 0.017) improvement to healing as indicated by a reduction in the surface area of the wound, over the 4-week study ...

2010-05-31

203

Hybrid Combined Cycles with Biomass and Waste Fired Bottoming Cycle - a Literature Study  

Energy Technology Data Exchange (ETDEWEB)

Biomass is one of the main natural resources in Sweden. The present low-CO{sub 2} emission characteristics of the Swedish electricity production system (hydro and nuclear) can be retained only by expansion of biofuel applications for energy purposes. Domestic Swedish biomass resources are vast and renewable, but not infinite. They must be utilized as efficiently as possible, in order to make sure that they meet the conditions for sustainability in the future. Application of efficient power generation cycles at low costs is essential for meeting this challenge. This applies also to municipal solid waste incineration with energy extraction, which should be preferred to its dumping in landfills. Hybrid dual-fuel combined cycle units are a simple and affordable way to increase the electric efficiency of biofuel energy utilization, without big investments, uncertainties or loss of reliability arising from complicated technologies. Configurations of such power cycles are ...

2002-02-01

204

Where the sun does not shine: Is sunshine protective against melanoma of the vulva?  

British Library Electronic Table of Contents (United Kingdom)

Intermittent sun exposure and sunburn are strong predictors of cutaneous malignant melanoma (CMM). On the other hand, melanomas may arise also in non-sun-exposed areas such as the vulva. However, little is known about a possible relationship between sun exposure and vulvar melanoma. Temporal and latitudinal dependencies of the incidence rates of vulvar melanoma were studied in comparison with those of CMM among Caucasians in Sweden, East Germany, USA and Victoria (Australia). The ratios of vulvar melanoma incidence rates to those of CMM tend to decrease with increasing CMM rates. The incidence rates of CMM have increased with time until recently, while those of vulvar melanoma have either decreased or remain constant. In USA vulvar melanoma incidence rates seem to increase from south to no...

2010-01-01

205

Understanding consumption-related sucralose emissions - A conceptual approach combining substance-flow analysis with sampling analysis  

British Library Electronic Table of Contents (United Kingdom)

This paper explores the potential of combining substance-flow modelling with water and wastewater sampling to trace consumption-related substances emitted through the urban wastewater. The method is exemplified on sucralose. Sucralose is a chemical sweetener that is 600 times sweeter than sucrose and has been on the European market since 2004. As a food additive, sucralose has recently increased in usage in a number of foods, such as soft drinks, dairy products, candy and several dietary products. In a field campaign, sucralose concentrations were measured in the inflow and outflow of the local wastewater treatment plant in Linkoping, Sweden, as well as upstream and downstream of the receiving stream and in Lake Roxen. This allows the loads emitted from the city to be estimated. A method c...

2010-01-01

206

Temperature profiles from rotational Raman lidar: parameter for the interpretation of PSC composition  

Energy Technology Data Exchange (ETDEWEB)

The depletion of stratospheric ozone is caused by chlorine species formed in heterogeneous processes on the surfaces of polar stratospheric cloud (PSC) particles. For studying local PSC formation processes in the Arctic a temperature lidar receiver was developed that makes use of the rotational Raman method, the only lidar technique for measuring atmospheric temperature profiles not perturbed by the presence of aerosols or cloud particles. The receiver was implemented in the mobile GKSS Raman lidar and transferred to Esrange (67.9 N, 21.1 E) near Kiruna in northern Sweden in winter 1997/98. Temperature data measured between January 22 and February 6, 1998, are presented and compared to model data analyzed by the European centre for medium-range weather forecast. Local temperature profiles are studied in three cases of type-Ib PSCs. This type is characterized by a low depolarization ratio. (orig.)

1999-07-01

207

Psychological test performance in foundry workers exposed to low levels of manganese  

Energy Technology Data Exchange (ETDEWEB)

A sample of 30 manganese-exposed foundry workers from two Swedish plants were examined with a partly computerized psychological test battery, comprised of 10 performance tests. Performance of the manganese-exposed workers was compared to that of a matched control group of 60 workers. Matching criteria were age, geographical area, type of work, and the results on a test of verbal comprehension. Performance of the exposed workers was inferior to that of the control group on tests of simple reaction time, digit span, and finger tapping. No correlations were found between performance and the present manganese exposure levels or the number of years employed in manganese work. The results seem to indicate that the present exposure standards for manganese, in Sweden 2.5 mg/m3 and in most other countries 5 mg/m3, are not sufficient to protect workers from negative effects on performance capacity.

1990-11-01

208

Overview of nuclear power plant equipment qualification issues and practices  

International Nuclear Information System (INIS)

This report presents a view of and commentary on the current status of equipment qualification (EQ) in nuclear industries of the major western nations. The introductory chapters discuss the concepts of EQ, the elements of EQ process and highlight some of the key issues in EQ. A brief review of industry practices and some of the prevalent industrial standards is presented, followed by an overview of current regulatory positions in the USA, France, Germany and Sweden. A summary and commentary on the latest research findings on issues relating to accident simulation, to aging simulation and some special topics related to EQ, has been contributed by Franklin Research Centre of Philadelphia. The last part of the report deals with equipment qualification in Canada and gives recommendations on EQ for new plants as well as currently operational CANDU nuclear power plants.

1984-05-15

209

Influence of weather on the behaviour of outdoor-wintered beef cattle in Scandinavia  

British Library Electronic Table of Contents (United Kingdom)

The aim of the present investigation was to study the effect of weather and available protection on the behaviour of outdoor-wintered beef cattle (Bos taurus). A herd of 78-85 cattle head was studied during four winter months in the Southwest of Sweden. Protection was offered by coniferous forest situated on and around the 12ha pasture, which we divided into protection categories. During 240h we observed 10 cows and 10 heifers as focal animals (each 3h/month) during day time and adjusted observation times to the altitude of the sun. Close to the animals and at an unprotected spot of the pasture we measured temperature, wind speed and solar radiation and combined these variables to a single measure called Wind Chill Temperature (WCT). During observations the animals were in the forest in 12...

2011-01-01

210

Geochemical modelling of acidification and recovery in forest soils and runoff waters  

Energy Technology Data Exchange (ETDEWEB)

The Model of Acidification of Groundwaters in Catchments (MAGIC) was used to simulate the impact of acidifying deposition and future recovery at the Gaardsjoen Covered Catchment Experiment, at a number of hypothetical stations defined by statistical variation of the Gaardsjoen data and at 20 forest monitoring sites in Southern Sweden. For the future predictions a decrease of sulphur deposition of more than 70% was assumed. This assumption is based on a full implementation of the agreements made under the second sulphur protocol from 1994. The modelled impact of reduced deposition on the soils and on the runoff waters was discussed. To complement the discussion on long-term trends in future run-off chemistry, data from Gaardsjoen has been used to asses the risk for short-term acid runoff episodes 26 refs, 23 figs, 7 tabs

1999-01-01

211

European wood pellet market integration - A study of the residential sector  

International Nuclear Information System (INIS)

The integration of European energy markets is a key goal of EU energy policy, and has also been the focal point of many scientific studies in recent years. International markets for coal, oil, natural gas and electricity have previously been investigated in order to determine the extent of the respective markets. This study enhances this field of research to bioenergy markets. Price series data and time series econometrics are used to determine whether residential sector wood pellet markets of Austria, Germany and Sweden are integrated. The results of the econometric tests show that the German and Austrian markets can be considered to be integrated, whereas the Swedish market is separate from the other two countries. Although increased internationalization of wood pellet markets is likely to contribute to European price convergence and market integration, this process is far from completed. (author)

2011-01-01

212

Effective dose equivalent concept in radiopharmaceutical dosimetry  

Energy Technology Data Exchange (ETDEWEB)

The Effective Dose Equivalent Concept defined by the International Commission on Radiological Protection in 1977 considers the risk from irradiation including both hereditary and somatic effects. This paper will deal with the definition of a concept for somatic effects only, the somatically significant dose equivalent. This is defined as the dose equivalent which if received by every member of the population, would be expected to produce the same total somatic injury to the population as does the actual dose equivalent received by various individuals. The somatically effective dose equivalent for a particular radiopharmaceutical is the weighted sum of the average dose equivalent to various organs. The dose equivalent to various organs can be derived from an extended MIRD formalism also considering the rest of body excluding the source volumes and the re iden e times in total body and the target organs. Examples are given for the calculation of somatically effective dose equivalent for ...

1981-06-01

213

Effective dose equivalent concept in radiopharmaceutical dosimetry  

International Nuclear Information System (INIS)

The Effective Dose Equivalent Concept defined by the International Commission on Radiological Protection in 1977 considers the risk from irradiation including both hereditary and somatic effects. This paper will deal with the definition of a concept for somatic effects only, the somatically significant dose equivalent. This is defined as the dose equivalent which if received by every member of the population, would be expected to produce the same total somatic injury to the population as does the actual dose equivalent received by various individuals. The somatically effective dose equivalent for a particular radiopharmaceutical is the weighted sum of the average dose equivalent to various organs. The dose equivalent to various organs can be derived from an extended MIRD formalism also considering the rest of body excluding the source volumes and the re iden e times in total body and the target organs. Examples are given for the calculation of somatically effective dose equivalent for ...

214

Downscaling of GCM forecasts to streamflow over Scandinavia  

DEFF Research Database (Denmark)

A seasonal forecasting technique to produce probabilistic and deterministic streamflow forecasts for 23 basins in Norway and northern Sweden is developed in this work. Large scale circulation and moisture fields, forecasted by the ECHAM4.5 model 4 months in advance, are used to forecast spring flows. The technique includes model output statistics (MOS) based on a non-linear Neural Network (NN) approach. Results show that streamflow forecasts from Global Circulation Model (GCM) predictions, for the Scandinavia region are viable and highest skill values were found for basins located in south-western Norway. The physical interpretation of the forecasting skill is that stations close to the Norwegian coast are directly exposed to prevailing winds from the Atlantic ocean, which constitute the principal source of predictive information from the atmosphere on the seasonal timescale.

2008-01-01

215

Comparison of selected approaches to finance renewable energy projects in European countries  

International Nuclear Information System (INIS)

A large number of proven technical solutions exists for the use of renewable energies. However, their dissemination is still too slow to meet the political goal of substituting for 8-15% of the primary energy demand in the European Union by the year 2010. Even renewable energy systems (RES) with an economic potential are only partly exploited. The FIRE research project financed partly in the JOULE program analyses and compares the means of financing RES in Austria, Denmark, Germany, the Netherlands, Spain, Sweden and the United Kingdom to put forward best practice recommendations so that renewable energy depolyments will occur at a faster rate. FIRE addresses to politicians, to potential investors and to project-developers. (orig./RHM)

216

Comparative activity of tigecycline and tetracycline on Gram-negative and Gram-positive bacteria revealed by a multicentre study in four North European countries  

British Library Electronic Table of Contents (United Kingdom)

Abstract Background: This study involves a multicentre surveillance of tigecycline and tetracycline activity against Gram-negative and Gram-positive bacteria from primary care centres (PCCs), general hospital wards (GHWs) and intensive care units (ICUs) in Denmark (n == 9), Finland (n == 10), Norway (n == 7) and Sweden (n == 19). Methods: The hospitals were each asked to test 30 consecutive Gram-positive and 30 Gram-negative clinical isolates. Supportive information accompanying each isolate included the study centre, ward level (PCC, GHW, or ICU), patient identification and source of the isolate. Minimum inhibitory concentrations (MICs) for tetracycline and tigecycline were determined with the Etest. Results: The isolates collected comprised 1610 Gram-negative and 1767 Gram-positive clini...

2011-01-01

217

Biofuels for electricity and heating - obstacles for increased utilization  

International Nuclear Information System (INIS)

The aim of this report is to describe the present situation regarding biomass utilization in small power plants, 0.5 - 20 MW fuel power. Also discussed are the most important technical, economical and environmental conditions which may prevent a fast expansion of small biomass fueled power plants for generation of district heating in smaller networks and also for electric power generation. Biofuels means a reduction of the net emission of carbon dioxide, but emission of other compounds are not very well known for this size of power plants. There are only a few biofueled power plants in Sweden and only a couple with less than 20 MW power supplied. New concepts are under development but not much have been achieved during the most recent years. 25 refs, 10 figs, 9 tabs.

218

Increased Prevalence of Albuminuria in HIV-Infected Adults with Diabetes  

Science.gov (United States)

ObjectiveHIV and type 2 diabetes are known risk factors for albuminuria, but no previous reports have characterized albuminuria in HIV-infected patients with diabetes.Research Design and MethodsWe performed a cross-sectional study including 73 HIV-infected adults with type 2 diabetes, 82 HIV-infected non-diabetics, and 61 diabetic control subjects without HIV. Serum creatinine >1.5 mg/dL was exclusionary. Albuminuria was defined as urinary albumin/creatinine ratio >30 mg/g.ResultsThe prevalence of albuminuria was significantly increased among HIV-infected diabetics (34% vs. 13% of HIV non-diabetic vs. 16% diabetic control, p?=?0.005). HIV status and diabetes remained significant predictors of albuminuria after adjusting for age, race, BMI, and blood pressure. Albumin/creatinine ratio correlated significantly with HIV viral load (r?=?0.28, p?=?0.0005) and HIV-infected subjects ...

2011-09-13

219

Targeted integration of baboon endogenous virus in the BEVI locus on human chromosome 6.  

Science.gov (United States)

The infection of cultured human cells with baboon endogenous virus (BEV) frequently leads to an association of viral DNA with a specific genetic locus (termed BEVI, for baboon endogenous virus infection) on chromosome 6. Restriction endonuclease digestion of DNA from BEV-infected human cells and their derived somatic cell clones frequently revealed a common cellular DNA sequence in the proximity of one of the junctions between cellular DNA and the integrated virus. We propose that a short cellular DNA sequence, repeated on chromosome 6 and separated by unique DNA sequences, presents a high-affinity target for the integration of BEV in human cells. PMID:6401843

1983-01-13

220

Susceptibility to invasive bacterial infections in children with sickle cell disease  

British Library Electronic Table of Contents (United Kingdom)

Individuals with sickle cell disease (SCD) demonstrate an increased susceptibility to invasive bacterial infections (IBI). The most common organisms causing IBI are Streptococcus pneumoniae, nontyphi Salmonella species and Haemophilus influenzae type b (Hib). IBI are the most common causes of death in children below 5 years of age with SCD. Increased susceptibility to IBI is because of several factors including dysfunctional antibody production and opsonophagocytosis as well as defective splenic clearance. Early diagnosis of Hib and pneumococcal infections combined with antibiotic prophylaxis and immunization programs, could lead to significant improvements in mortality, especially in Africa. Pediatr Blood Cancer. 2010;55:401-406. Copyright 2010 Wiley-Liss, Inc.

2010-01-01

221

Selective vulnerability of dorsal root ganglia neurons in experimental rabies after peripheral inoculation of CVS-11 in adult mice  

British Library Electronic Table of Contents (United Kingdom)

The involvement of dorsal root ganglia was studied in an in vivo model of experimental rabies virus infection using the challenge virus standard (CVS-11) strain. Dorsal root ganglia neurons infected with CVS in vitro show prolonged survival and few morphological changes, and are commonly used to study the infection. It has been established that after peripheral inoculation of mice with CVS the brain and spinal cord show relatively few neurodegenerative changes, but detailed studies of pathological changes in dorsal root ganglia have not previously been performed in this in vivo experimental model. In this study, adult ICR mice were inoculated in the right hindlimb footpad with CVS. Spinal cords and dorsal root ganglia were evaluated at serial time points for histopathological and ultrastru...

2009-01-01

222

Randomised, placebo-controlled trial to evaluate co-trimoxazole to reduce mortality and morbidity in HIV-infected post-natal women in Zambia (TOPAZ)  

British Library Electronic Table of Contents (United Kingdom)

Summary Objective- To evaluate the role of prophylactic trimethoprim-sulfamethoxazole (co-trimoxazole) antibacterial prophylaxis in reducing morbidity and mortality in HIV-infected post-natal women in southern Africa. Methods- Double-blind placebo-controlled trial. HIV-infected women with WHO stage 2 or 3 HIV disease who had recently delivered in the Department of Obstetrics and Gynaecology at the University Teaching Hospital, Lusaka, Zambia were randomised to receive daily co-trimoxazole (cotox) or matched placebo daily for the duration of the trial. Participants were followed up for a minimum of 1-year. Primary outcome measures were mortality from any cause or hospital admission and serious adverse events. Results- Of 600 women randomised, follow-up information was available from 355 (18...

2011-01-01

223

Prevalence and Incidence of HCV Infection among Vietnam Heroin Users with Recent Onset of Injection  

British Library Electronic Table of Contents (United Kingdom)

HCV infection continues to spread at an alarming rate among IDU populations. The available evidence suggests that HCV is acquired relatively quickly following onset of injection. However, there are few prospective studies of HCV acquisition, particularly among IDU populations in resource-poor settings. A sample of young male heroin injectors with recent onset of injection (<4?years) was recruited in Hanoi, Vietnam for a prospective assessment of the early course of injection (n?=?179). Both behavioral and biological assessments (including detailed retrospective assessment of injection initiation) were conducted at baseline and repeated at 6-month intervals for a period of 16?months. Variables associated with HCV infection (p value?p value?=?0.0005). In multivariate logistic regression anal...

2010-01-01

224

Outcome of peripherally inserted central venous catheters in surgical and medical neonates  

British Library Electronic Table of Contents (United Kingdom)

Background/Purpose: Peripherally inserted central venous catheters (PICCs) are commonly used for neonatal vascular access. The aim of this study was to look at PICC line complication rates and possible predictors of PICC infection in a neonatal intensive care unit. Method: This was a prospective study of 226 neonates who had PICCs on our neonatal intensive care unit between January 2006 and June 2009. Complete data was available on 218 neonates who had 294 PICC lines. Criteria for catheter-related sepsis was positive blood cultures (peripheral/central) and/or a positive catheter tip culture after removal in the presence of a clinical suspicion of line sepsis. Results: Of 218 neonates, 132 (169 lines) were medical, and 86 (125 lines) were surgical. Our PICC line infection rate was 17 infect...

2011-01-01

225

Epidemic spreading with nonlinear infectivity in weighted scale-free networks  

CERN Document Server

In this paper, we investigate the epidemic spreading for SIR model in weighted scale-free networks with nonlinear infectivity, where the transmission rate in our analytical model is weighted. Concretely, we introduce the infectivity exponent $\\alpha$ and the weight exponent $\\beta$ into the analytical SIR model, then examine the combination effects of $\\alpha$ and $\\beta$ on the epidemic threshold and phase transition. We show that one can adjust the values of $\\alpha$ and $\\beta$ to rebuild the epidemic threshold to a finite value, and it is observed that the steady epidemic prevalence $R$ grows in an exponential form in the early stage, then follows hierarchical dynamics. Furthermore, we find $\\alpha$ is more sensitive than $\\beta$ in the transformation of the epidemic threshold and epidemic prevalence, which might deliver some useful information or new insights in the epidemic spreading and the correlative immunization schemes.

2009-01-01

226

Effect of host nutrition on immunity and local immune response of rabbits to Obeliscoides cuniculi  

International Nuclear Information System (INIS)

In a series of experiments carried out on young and adult rabbits the effect of isocaloric low protein diets containing 4% or 8% protein compared with a diet containing 21% protein on Obeliscoides cuniculi infection was studied. The pathogenesis, resistance and local immunity were assessed after single infections with 10,000 larvae or reinfection with 5000 larvae. Live weight gain was reduced in young and adult rabbits fed the low protein diets, but the establishment of parasites was not substantially influenced by protein deprivation. However, development of worms in the histotrophic phase and parasite fecundity were impaired in association with the low protein diet. Moreover, mild anaemia as well as changes in the mucosal immune response as a result of infection were related to the level of dietary protein. (author). 30 refs, 6 figs, 5 tabs.

1987-05-11

227

Changing Treatment Paradigms Hepatitis C Virus in HIV-Infected Patients  

British Library Electronic Table of Contents (United Kingdom)

The evaluation of hepatic histology and treatment of hepatitis C virus (HCV)/HIV-coinfected patients is rapidly changing. HCV has become an important cause of mortality in HIV-infected patients. Consequently, assessment of liver histology in all coinfected patients is particularly important. The evaluation of hepatic histology is shifting from reliance on the liver biopsy toward noninvasive modalities. Additionally, the importance of HCV-associated morbidity and mortality in HIV-infected patients has prompted increasing numbers of these patients to be HCV treatment candidates. Prospective trials in coinfected patients have reported lower sustained virologic responses compared to HCV-monoinfected patients. Consequently, the numbers of coinfected nonresponders to pegylated interferon/ribavir...

2007-01-01

228

Benign lymphoepithelial lesion of the parotid gland in AIDS patients: CT characteristics  

International Nuclear Information System (INIS)

Contrast agent-enhanced CT scans in nine male patients with histologically proved benign lymphoepithelial lesions of the perotid gland were reviewed. All scans showed cystic-appearing masses with peripheral rim enhancement corresponding to the macroscopic appearance of the lesion. Five patients were seropositive for human immunodeficiency virus (HIV) infection or had infections seen in acquired immunodeficiency syndrome. Three patients were members of high-risk groups. Only one patient had symptoms of the SICCA syndrome. Once a rare cause of parotid gland enlargement, benign lymphoepithelial lesions have recently been seen with increasing frequency in patients with HIV infection. Although the CT appearance is not pathognomic, correlation results of aspiration cytology and with clinical history can lead to a preoperative diagnosis of a benign lymphoepithelial lesion.

229

A Hypothesis: Supplementation with Mushroom-Derived Active Compound Modulates Immunity and Increases Survival in Response to Influenza Virus (H1N1) Infection.  

Science.gov (United States)

We hypothesize that the mushroom-derived active compound may be a potential strategy for increasing survival in response to influenza virus (H1N1) infection through the stimulation of host innate immune response. The validity of the hypothesis can be tested by immune response to influenza infection as seen through survival percentage, virus clearance, weight loss, natural killer cell cytotoxicity, Tumor Necrosis Factor-? (TNF-?) and Interferon-gamma (IFN-?) levels, lytic efficiency in the spleens of mice and inducible nitric oxide synthase mRNA expressions in RAW 264.7 murine macrophage cells. The hypothesis may improve people's quality of life, reduce the medical cost of our healthcare system and eliminate people's fears of influenza outbreak. PMID:21660092

2011-03-20

230

New trends in electricity pricing in Sweden from a utility perspective  

Energy Technology Data Exchange (ETDEWEB)

Sweden is facing a re-structured electricity market beginning January 1, 1996, implying full competition in the purchasing and selling of electricity. The transmission and distribution of electricity will remain as a franchised monopoly and this business has to be strictly separated from the electricity trading. In the monopolistic environment, pricing of electricity has been based on more or less relevant costs and a resonable rate of return. The energy charges have reflected the system short range marginal costs while the demand and fixed charges have been adapted to give a total cost level corresponding to the system average cost. Tariffs of this type, known as time-of-use tariffs, have stimulated peak shaving during peak load (high cost hours) and valley filling during low load (low cost hours), increasing the load factor. Restructuring will influence the pricing in several ways. Pricing of transmission and distribution services will be based on costs and will ...

1996-03-01

231

Emissions to air in Sweden of sulphur dioxide, nitrogen oxides and carbon dioxide in 1995; Utslaepp till luft i Sverige av svaveldioxid, kvaeveoxider och koldioxid, 1995  

Energy Technology Data Exchange (ETDEWEB)

In this report statistical data are presented on a national level on emissions to air in Sweden in 1995 of sulphur dioxide (SO{sub 2}), nitrogen oxides (NO{sub x}, counted as NO{sub 2}) and carbon dioxide (CO{sub 2}). Corresponding data for 1980 and 1994 are presented as a comparison. For CO{sub 2} data for 1990 and 1994 are presented as a comparison. The total amount of SO{sub 2}-emissions to air in 1995 were 94 000 tons, which means a decrease by 3 percent since 1994. The total amount of NO{sub x}-emissions to air were 362 000 tons, a 3 percent decrease since 1993. The total amount of CO{sub 2}-emissions to air were 63 200 000 tons, an increase by 7 percent compared with 1990. Differentiated data are given for various sources of emissions, i.e. combustion of fuels, industrial processes and mobile sources. Further data are presented on emission of SO{sub 2} and NO{sub x} from combustion, separately for electricity and heat production. The total amount of SO{sub 2} ...

1996-12-01

232

An environmentally sustainable transport system in Sweden. A scenario study  

Energy Technology Data Exchange (ETDEWEB)

This is a short version of a scenario study concerning the possibilities to reach an Environmentally Sustainable Transport system in Sweden in a perspective of 30 years. The aim of the scenario study has been to describe one of several possible paths from today`s transport system to an environmentally adopted one. However, this does not imply that the task is to predict how such a transformation can be accomplished. The aim is rather to illustrate what such transformation require in the form of political decisions. The transformation of the transport system in to an environmentally adopted one, is primarily treated as a political problem, and a political perspective has accordingly been chosen for the study. In this English version of the scenario, the carbon dioxide problem is used to illuminate the many conflicts in goals and other problem that will attend an environmental adoption of the Swedish transport system, and to highlight the analytical points of ...

1997-02-01

233

50 Hz - electromagnetic fields. Regulations concerning non-ionizing radiation; 50 Hz-Magnetfelder. Gesetzgeberische Moeglichkeiten auf dem Gebiet der nichtionisierenden Strahlung und Handlungsprogramme in Schweden  

Energy Technology Data Exchange (ETDEWEB)

As a central supervision authority the National Electrical Safety Board (Elsaekerhetsverket) has the main responsibility for the safety of high voltage power lines and other power electric equipment. It is therefore also responsible for questions concerning the effects of power frequency magnetic fields on the environment. According to the rules it is not allowed to draw overhead power lines with a voltage exceeding 1000 V above buildings. Their minimum distance to buildings must not be below 5 m. For regions comprised by rural development plans the directions prescribe a minimum distance of 10 m between buildings and high voltage transmission lines with a voltage of 55 kV or more. The publication of two large epidemiological studies about exposure to magnetic fields and cancer in Sweden in autumn 1992 has brought magnetic fields problems to general notice again. A statement on health risks form electromagnetic fields was issued by SSI in January 1993. SSI and ...

1993-06-01

234

Zoonoses-With Friends Like This, Who Needs Enemies?  

UK PubMed Central (United Kingdom)

Zoonoses are infections that are spread from animals to humans. Most often, humans are “dead-end” hosts, meaning that there is no subsequent human-to-human transmission. If one considers...Full Text Available

2008-01-01

235

Variant influenza virus hemagglutinin that induces fusion at elevated pH.  

UK PubMed Central (United Kingdom)

The hemagglutinin (HA) glycoprotein of influenza virus performs two critical roles during infection: it binds virus to cell surface sialic acids, and under mildly acidic conditions it induces fusion...Full Text Available

1986-02-01

236

Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans  

UK PubMed Central (United Kingdom)

Bloodstream infection by highly antibiotic-resistant bacteria, such as vancomycin-resistant Enterococcus (VRE), is a growing clinical problem that increasingly defies medical intervention....Full Text Available

2010-12-01

237

Value of individual household water supplies in the maintenance phase of a schistosomiasis control programme in Saint Lucia, after chemotherapy*  

UK PubMed Central (United Kingdom)

Between 1970 and 1975, the incidence of new Schistosoma mansoni infections was reduced in 5 villages after each household was provided with its individual water supply and community...Full Text Available

1982-01-01

238

Validation of Cultivation and PCR Methods for Diagnosis of Lyme Neuroborreliosis?  

UK PubMed Central (United Kingdom)

Borrelial infection may manifest with a wide range of clinical signs, and in many cases, microbiological findings are essential for a proper diagnosis. This study included 48 patients with a working...Full Text Available

2008-10-01

239

Urinary tract infection in children.  

UK PubMed Central (United Kingdom)

During 1968-77, 572 consecutive children with one or more positive urine cultures who were referred by their family doctors to one paediatric surgical outpatient clinic were investigated and prospectively...Full Text Available

1984-08-04

240

Urethral syndrome in women attending a clinic for sexually transmitted diseases.  

UK PubMed Central (United Kingdom)

Of 107 women investigated for frequency of micturition and dysuria, 21 had gonorrhoea, 14 chlamydial urethritis, eight an Escherichia coli urinary tract infection, 18 candidosis, 12 trichomoniasis,...Full Text Available

1983-06-01

241

Transmission of Salmonella mbandaka to cattle from contaminated feed.  

UK PubMed Central (United Kingdom)

Salmonella mbandaka was isolated from cattle on three dairy farms. The duration of infection was less than four weeks and none of the animals became clinically ill. The animals had all consumed a diet...Full Text Available

1982-04-01

242

Transcriptional mapping of the 3' end of the bovine syncytial virus genome.  

UK PubMed Central (United Kingdom)

The bovine syncytial virus, a member of the retroviral subfamily Spumavirinae, causes a persistent, asymptomatic infection in cattle. Nucleotide sequence analysis of the viral genome revealed two overlapping...Full Text Available

1994-02-01

243

Tinea nigra by Hortaea werneckii, a report of 22 cases from Mexico  

UK PubMed Central (United Kingdom)

Tinea nigra is a superficial mycosis caused by Hortaea werneckii. It is an infrequent asymptomatic infection that affects human palms and soles, and is mostly observed in tropical...Full Text Available

2008-01-01

244

Tick-Borne Relapsing Fever in British Columbia, Canada: First Isolation of Borrelia hermsii  

UK PubMed Central (United Kingdom)

The spirochete that causes tick-borne relapsing fever, Borrelia hermsii, was isolated in pure culture during 1995 and 1996 from three acutely ill human patients infected in southern...Full Text Available

1998-12-01

245

The relationships of salmonellae from infected broiler flocks, transport crates or processing plants to contamination of eviscerated carcases.  

UK PubMed Central (United Kingdom)

Three flocks raised for broiler or roaster performance tests were studied to determine the incidence and sources of salmonellae during the growing period, transport and processing and to relate these...Full Text Available

1982-07-01

246

The protozoan parasite Theileria annulata alters the differentiation state of the infected macrophage and suppresses musculoaponeurotic fibrosarcoma oncogene (MAF) transcription factors  

UK PubMed Central (United Kingdom)

AbstractThe tick-borne protozoan parasite Theileria annulata causes a debilitating disease of cattle called Tropical Theileriosis. The parasite predominantly invades...Full Text Available

2009-08-01

247

The Influence of Abacavir and Other Antiretroviral Agents on Virologic Response to Hepatitis C Virus Therapy Among Antiretroviral-Treated HIV-Infected Patients  

UK PubMed Central (United Kingdom)

BackgroundIt remains unclear if certain antiretroviral medications, particularly abacavir, compromise response to hepatitis C virus (HCV) therapy. Such data can inform...Full Text Available

2010-01-01

248

The Case for Selection at CCR5-?32  

UK PubMed Central (United Kingdom)

The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Δ32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested...Full Text Available

2005-11-01

249

The Blind NasoTracheal Aspiration Method Is Not a Useful Tool for Pathogen Detection of Pneumonia in Children  

UK PubMed Central (United Kingdom)

BackgroundAcute lower respiratory infection (ALRI) is a major cause of hospitalization for children in China, while the etiological diagnosis of ALRI remains a challenge. This study...Full Text Available

250

Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs  

UK PubMed Central (United Kingdom)

BackgroundTrypanosoma cruzi, the etiologic agent of Chagas Disease, is a major vector borne health problem in Latin America and an emerging...Full Text Available

251

Temporal Correlations between Tick Abundance and Prevalence of Ticks Infected with Borrelia burgdorferi and Increasing Incidence of Lyme Disease  

UK PubMed Central (United Kingdom)

The abundance of host-seeking Ixodes scapularis nymphs, the principal vector for the Lyme disease agent, Borrelia burgdorferi, in Old Lyme, Lyme, and East Haddam, Connecticut,...Full Text Available

1998-05-01

252

Survival of HIV-Infected Adolescents on Antiretroviral Therapy in Uganda: Findings from a Nationally Representative Cohort in Uganda  

UK PubMed Central (United Kingdom)

BackgroundAdolescents have been identified as a high-risk group for poor adherence to and defaulting from combination antiretroviral therapy (cART) care. However, data on outcomes...Full Text Available

253

Sugarcane Rust Inoculations  

Science.gov (United States)

Sugarcane rusts, brown (caused by Puccinia melanocephala) and orange (caused by P. kuehnii), are agronomically important diseases in Florida. Cultivar resistance is the best means of managing these diseases. Unfortunately, natural infection of brown rust is not always efficient in determining resist...

254

Sternal plate fixation for sternal wound reconstruction: initial experience (Retrospective study)  

UK PubMed Central (United Kingdom)

BackgroundMedian sternotomy infection and bony nonunion are two commonly described complications which occur in 0.4 - 5.1% of cardiac procedures. Although relatively infrequent,...Full Text Available

255

Spatial Re-Establishment Dynamics of Local Populations of Vectors of Chagas Disease  

UK PubMed Central (United Kingdom)

BackgroundPrevention of Chagas disease depends mainly on control of the insect vectors that transmit infection. Unfortunately, the vectors have been resurgent in some areas. It is...Full Text Available

256

Sparganosis in the Lumbar Spine : Report of Two Cases and Review of the Literature  

UK PubMed Central (United Kingdom)

Sparganosis is a rare parasitic infection affecting various organs, including the central nervous system, especially the lumbar epidural space. This report describes the identification of disease and...Full Text Available

2011-04-01

257

Some characteristics of a secreted chlamydial antigen recognized by IgG from C. trachomatis patient sera.  

UK PubMed Central (United Kingdom)

Chlamydia trachomatis serovars release a glycolipid antigen (GLXA) into the culture supernatant during the infective cycle. This antigen is recognized by IgG isolated from humans with a natural chlamydial...Full Text Available

1989-12-01

258

Significant asymptomatic bacteriuria among Nigerian type 2 diabetics.  

UK PubMed Central (United Kingdom)

Significant asymptomatic bacteriuria is a risk factor for symptomatic urinary infection and septicemia among predisposed individuals such as diabetics. We investigated the pattern of asymptomatic bacteriuria...Full Text Available

2003-05-01

259

Serratia odorifera biogroup 1 causing an invasive human infection.  

UK PubMed Central (United Kingdom)

Serratia odorifera biogroup 1 was isolated from the blood and urine of an alcoholic male with cirrhosis and signs of septic shock. The organism is rarely reported to occur in clinical specimens. This...Full Text Available

1988-06-01

260

Seroprevalence of HIV-1 and HIV-2 infection among children diagnosed with protein-calorie malnutrition in Nigeria.  

UK PubMed Central (United Kingdom)

Excessive weight loss due to protein calorie malnutrition (PCM) is a significant problem in Nigerian children. This syndrome may be difficult to differentiate from the wasting disease caused by human...Full Text Available

1993-04-01

261

Selective Degradation of Newly Synthesized Nonmessenger Simian Virus 40 Transcripts  

UK PubMed Central (United Kingdom)

By pretreating simian virus 40-infected BSC-1 cells with glucosamine, [3H]uridine labeling of both cellular and viral RNA can be halted instantaneously by addition of cold uridine. We have...Full Text Available

1978-11-01

262

Scaling up prevention programmes to reduce the sexual transmission of HIV in China  

UK PubMed Central (United Kingdom)

Background Since 2007, sex has been the major mode of HIV transmission in China, accounting for 75% of new infections in 2009. Reducing sexual transmission is a major challenge for China...Full Text Available

2010-12-01

263

Roxithromycin compared with erythromycin against genitourinary chlamydial infections.  

UK PubMed Central (United Kingdom)

The efficacy and safety of roxithromycin 300 mg once a day was compared with that of erythromycin 500 mg twice a day, both for seven days, in a double blind study of 281 patients (188 men, 93 women)...Full Text Available

1989-01-01

264

Role of Group A Streptococcal Virulence Factors in Adherence to Keratinocytes  

UK PubMed Central (United Kingdom)

To evaluate the role of putative group A streptococcal virulence factors in the initiation of skin infections, we compared the adherence of a wild-type M49-protein skin-associated strain to that of...Full Text Available

2000-03-01

265

Rifampin pharmacokinetics in children, with and without human immunodeficiency virus infection, hospitalized for the management of severe forms of tuberculosis  

UK PubMed Central (United Kingdom)

BackgroundRifampin is a key drug in antituberculosis chemotherapy because it rapidly kills the majority of bacilli in tuberculosis lesions, prevents relapse and thus enables 6-month...Full Text Available

266

Regulation of DAF-16-mediated Innate Immunity in Caenorhabditis elegans*  

UK PubMed Central (United Kingdom)

Activation of the innate immune system results in a rapid microbicidal response against microorganisms, which needs to be fine-tuned because uncontrolled immune responses can lead to infection and cancer,...Full Text Available

2009-12-18

267

Recurrent miscarriage and variant alleles of mannose binding lectin, tumour necrosis factor and lymphotoxin ? genes  

UK PubMed Central (United Kingdom)

Variant alleles of the mannose binding lectin (MBL) gene are associated with increased susceptibility to infection and polymorphisms of tumour necrosis factor and lymphotoxin alpha genes (TNF, LTA)...Full Text Available

2001-12-01

268

Recent changes in the epidemiology and management of extended-spectrum ?-lactamase-producing Enterobacteriaceae  

UK PubMed Central (United Kingdom)

Since 2000, Escherichia coli producing CTX-M enzymes (especially CTX-M-15) have emerged worldwide as important causes of community-onset urinary tract and blood stream infections due...Full Text Available

269

Rapid, sensitive detection of Mycoplasma pneumoniae in simulated clinical specimens by DNA amplification.  

UK PubMed Central (United Kingdom)

The polymerase chain reaction (PCR) was investigated as a means of diagnosing Mycoplasma pneumoniae infections. The target DNA sequence was a 375-bp segment of the P1 virulence protein. This DNA segment...Full Text Available

1992-12-01

270

Randomized placebo-controlled trial on azithromycin to reduce the morbidity of bronchiolitis in Indigenous Australian infants: rationale and protocol  

UK PubMed Central (United Kingdom)

BackgroundAcute lower respiratory infections are the commonest cause of morbidity and potentially preventable mortality in Indigenous infants. Infancy is also a critical time for...Full Text Available

271

Radial keratoneuritis as a presenting sign in acanthamoeba keratitis.  

Science.gov (United States)

The visual outcomes of Acanthamoeba keratitis, a rare cause of corneal infection, can be devastating. This paper reports two contact lens wearers with severe pain and photophobia who presented to the emergency room. Biomicroscopy revealed radial keratoneuritis in both individuals. Tissue culture on a nonnutrient agar plate with Escherichia coli overlay resulted in a heavy growth of Acanthamoeba. The inpatient treatment included 0.02% polyhexamethylene biguanide, chlorhexidine, neomycin/polymyxin B/bacitracin (Neosporin), and oral fluconazole, which successfully controlled the corneal infection and improvement in the best corrected visual acuity in both patients. Infection did not recur during the 12-month follow-up period. Acanthamoeba keratitis can present as radial keratoneuritis, mimicking other common corneal infections resulting in diagnostic and treatment delays. Early diagnosis and prudent ...

2011-07-01

272

Pseudomonas aeruginosa selective adherence to and entry into human endothelial cells.  

UK PubMed Central (United Kingdom)

The pathogenesis of Pseudomonas aeruginosa disseminated infections depends on bacterial interaction with blood vessels. We have hypothesized that in order to traverse the endothelial barrier, bacteria...Full Text Available

1994-12-01

273

Prevalence of sexually transmissible pathogens in semen from asymptomatic male infertility patients with and without leukocytospermia  

UK PubMed Central (United Kingdom)

ObjectiveTo determine the prevalence of pathogens that cause sexually transmitted infections (STIs) in semen from asymptomatic male infertility patients with and...Full Text Available

2007-05-01

274

Prevalence and Characterization of Human Shigella Infections in Henan Province, China, in 2006 ?  

UK PubMed Central (United Kingdom)

In 2006, 3,531 fecal samples were collected from patients with diarrhea in Henan Province, China. A total of 467 (13.2%) Shigella strains were isolated and serotyped. Seventy-one...Full Text Available

2011-01-01

275

Pregravid BMI is associated with dietary restraint and psychosocial factors during pregnancy1  

UK PubMed Central (United Kingdom)

The objective was to investigate the association of pregravid weight status, dietary restraint and psychosocial factors during pregnancy. We used data from the Pregnancy, Infection and Nutrition...Full Text Available

2009-03-01

276

Pharmacokinetics and bioavailability of intravenous-to-oral enoxacin in elderly patients with complicated urinary tract infections.  

UK PubMed Central (United Kingdom)

The pharmacokinetics of oral fluoroquinolone antibiotics in normal volunteers have been studied extensively; however, limited patient data exist. Enoxacin steady-state pharmacokinetics and bioavailability...Full Text Available

1990-10-01

277

Phaeoisaria clematidis as a Cause of Keratomycosis  

UK PubMed Central (United Kingdom)

We report the first case of human infection by Phaeoisaria clematidis. This fungus caused a corneal ulcer in a Brazilian man who had previously suffered an eye injury. Diagnosis was...Full Text Available

2000-06-01

278

Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis  

UK PubMed Central (United Kingdom)

BackgroundThe long latent stage seen in syphilis, followed by chronic central nervous system infection and inflammation, can be explained by the persistence of atypical cystic and...Full Text Available

279

Persistence in herpes simplex virus infections.  

UK PubMed Central (United Kingdom)

Diseases of man caused by the virus of herpes simplex fall into two broad categories. The primary disease occurs only once in any individual's life and is caused by transmission of virus from an already...Full Text Available

1978-09-01

280

Pathogenesis of the Human Opportunistic Pathogen Pseudomonas aeruginosa PA14 in Arabidopsis1  

UK PubMed Central (United Kingdom)

The human opportunistic pathogen Pseudomonas aeruginosa strain PA14 is a multihost pathogen that can infect Arabidopsis. We found that PA14 pathogenesis in Arabidopsis involves the...Full Text Available

2000-12-01

281

Passive immunity to feline leukemia: evaluation of immunity from dams naturally infected and experimentally vaccinated.  

UK PubMed Central (United Kingdom)

Antibodies against feline leukemia virus (FeLV) and the feline oncornavirus-associated cell membrane antigen (FOCMA) were transferred from pregnant cats to their suckling kittens. All of these kittens...Full Text Available

1977-04-01

282

Outbreak of Infection with a Multiresistant Klebsiella pneumoniae Strain Associated with Contaminated Roll Boards in Operating Rooms  

UK PubMed Central (United Kingdom)

An outbreak with a multiresistant Klebsiella pneumoniae (MRKP) strain among seven patients admitted to the adult intensive care unit (ICU) of a regional teaching hospital in The Netherlands...Full Text Available

2005-10-01

283

Oral manifestations of HIV infection in children and adults receiving highly active anti-retroviral therapy [HAART] in Dar es Salaam, Tanzania  

UK PubMed Central (United Kingdom)

BackgroundThe aim of the study was to compare the prevalence and types of HIV-related oral lesions between children and adult Tanzanian patients on HAART with those not on HAART...Full Text Available

284

Novel Human Erythrovirus Associated with Transient Aplastic Anemia  

UK PubMed Central (United Kingdom)

Erythrovirus (formerly parvovirus) B19 causes a wide range of diseases in humans, including anemia due to aplastic crisis. Diagnosis of B19 infection relies on serology and the detection of viral DNA...Full Text Available

1999-08-01

285

Novel Approach for Differential Diagnosis of HIV Infections in the Face of Vaccine-Generated Antibodies  

UK PubMed Central (United Kingdom)

SummaryBecause increasing numbers of HIV vaccine candidates are being tested globally, it is essential to differentiate vaccine-from virus-induced antibodies. Most of the currently...Full Text Available

2006-11-01

286

Neural injury following stroke: are Toll-like receptors the link between the immune system and the CNS?  

UK PubMed Central (United Kingdom)

The CNS can exhibit features of inflammation in response to injury, infection or disease, whereby resident cells generate inflammatory mediators, including cytokines, prostaglandins, free radicals and...Full Text Available

2010-08-01

287

Mycobacterium tuberculosis Chaperonin 10 Is Secreted in the Macrophage Phagosome: Is Secretion Due to Dissociation and Adoption of a Partially Helical Structure at the Membrane?  

UK PubMed Central (United Kingdom)

To confirm that Mycobacterium tuberculosis chaperonin 10 (Cpn10) is secreted outside the live bacillus, infected macrophages were examined by electron microscopy. This revealed that...Full Text Available

2003-07-01

288

Mutant ?-Synuclein Overexpression Mediates Early Proinflammatory Activity  

UK PubMed Central (United Kingdom)

Microglia provide immune surveillance for the brain through both the removal of cellular debris and protection against infection by microorganisms and “foreign” molecules. Upon...Full Text Available

2009-10-01

289

Multidrug resistant Kluyvera ascorbata septicemia in an adult patient: a case report  

UK PubMed Central (United Kingdom)

IntroductionKluyvera ascorbata has become increasingly significant due to its potential to cause a wide range of infections, as well as its ability to transfer gene...Full Text Available

290

Morules in endometrial carcinoma and benign endometrial lesions differ from squamous differentiation tissue and are not infected with human papillomavirus  

UK PubMed Central (United Kingdom)

Background: Squamous differentiation/squamous metaplasia is often associated with endometrial adenocarcinoma and benign lesions, such as endometrial hyperplasia and chronic endometritis....Full Text Available

2004-09-01

291

Molecular Mechanistic Insights into the Endothelial Receptor Mediated Cytoadherence of Plasmodium falciparum-Infected Erythrocytes  

UK PubMed Central (United Kingdom)

Cytoadherence or sequestration is essential for the pathogenesis of the most virulent human malaria species, Plasmodium falciparum (P. falciparum). Similar to leukocyte-endothelium...Full Text Available

292

Molecular Evidence of Bartonella Infection in Domestic Dogs from Algeria, North Africa, by Polymerase Chain Reaction (PCR)  

UK PubMed Central (United Kingdom)

Bartonella species are being recognized as important bacterial human and canine pathogens, and are associated with multiple arthropod vectors. Bartonella DNA extracted...Full Text Available

2010-08-05

293

Molecular Epidemiology of Escherichia coli Producing Extended-Spectrum ?-Lactamases Isolated in Rome, Italy?  

UK PubMed Central (United Kingdom)

Escherichia coli strains producing extended-spectrum β-lactamases (ESBLs) are a major problem in many different hospitals worldwide, causing outbreaks as well as sporadic infections....Full Text Available

2008-01-01

294

Media reporting of tenofovir trials in Cambodia and Cameroon  

UK PubMed Central (United Kingdom)

BackgroundTwo planned trials of pre-exposure prophylaxis tenofovir in Cambodia and Cameroon to prevent HIV infection in high-risk populations were closed due to activist pressure...Full Text Available

295

Macrophage induction of T-suppressor cells in pesticide-exposed and protozoan-infected mice.  

UK PubMed Central (United Kingdom)

The use of infectious pathogens has allowed the detection of the development of synergism between pathogens and ubiquitous environmental chemical contaminants. This synergism has been demonstrated to...Full Text Available

1982-02-01

296

Liver Flukes: the Malady Neglected  

UK PubMed Central (United Kingdom)

Liver fluke disease is a chronic parasitic inflammatory disease of the bile ducts. Infection occurs through ingestion of fluke-infested, fresh-water raw fish. The most well-known species that cause...Full Text Available

2011-05-01

297

Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS  

UK PubMed Central (United Kingdom)

BackgroundHuman immunodeficiency virus type 1 (HIV-1) infection frequently causes neurologic disease, which is the result of viral replication and activation of macrophages and microglia...Full Text Available

298

Isolation of gram-positive rods that resemble but are clearly distinct from Actinomyces pyogenes from mixed wound infections.  

UK PubMed Central (United Kingdom)

Beginning in 1990, gram-positive rods resembling Actinomyces pyogenes were found with increasing frequency in mixed cultures from various infectious processes, most of them from patients with otitis,...Full Text Available

1993-05-01

299

Isolation of Mycoplasma pneumoniae from the human urogenital tract.  

UK PubMed Central (United Kingdom)

Mycoplasma pneumoniae is a common etiologic agent of lower respiratory tract infections in humans. However, it has been reported previously that the organism has occasionally been isolated from sites...Full Text Available

1995-11-01

300

Intragenomic conflict in populations infected by Parthenogenesis Inducing Wolbachia ends with irreversible loss of sexual reproduction  

UK PubMed Central (United Kingdom)

BackgroundThe maternally inherited, bacterial symbiont, parthenogenesis inducing (PI) Wolbachia, causes females in some haplodiploid insects to produce daughters...Full Text Available

301

Intracellular ribonucleoprotein complexes of visna virus are infectious.  

UK PubMed Central (United Kingdom)

Sheep choroid plexus cells infected with visna virus produce intracytoplasmic viral ribonucleoprotein complexes with sedimentation values of 120S to 200S and buoyant densities of 1.29 to 1.32 g/cm3....Full Text Available

1982-06-01

302

Interactions of Antibiotics and Methanolic Crude Extracts of Afzelia Africana (Smith.) Against Drug Resistance Bacterial Isolates  

UK PubMed Central (United Kingdom)

Infection due to multidrug resistance pathogens is difficult to manage due to bacterial virulence factors and because of a relatively limited choice of antimicrobial agents. Thus, it is imperative to...Full Text Available

303

Inflammatory Bowel Disease in Children, an Evolving Problem in Kuwait  

UK PubMed Central (United Kingdom)

Background/Aims:Inflammatory bowel disease (IBD) was previously thought a rare disease among children in Kuwait since most diarrhea cases were attributed to infections....Full Text Available

2011-09-01

304

Infection of Dendritic Cells by a ?2-Herpesvirus Induces Functional Modulation1  

UK PubMed Central (United Kingdom)

The murine γ-herpesvirus-68 (γHV68) establishes viral latency in dendritic cells (DCs). In the present study, we examined the specific consequences...Full Text Available

2005-09-01

305

Infected foot ulcers in male and female diabetic patients: a clinico-bioinformative study  

UK PubMed Central (United Kingdom)

BackgroundThe study aimed at (i) characterizing the mode of transmission of blaCTX-M and blaTEM-1 among extended-spectrum-β-lactamase...Full Text Available

306

Increased prevalence of antibodies to enteropathogenic Yersinia enterocolitica virulence proteins in relatives of patients with autoimmune thyroid disease  

UK PubMed Central (United Kingdom)

Infections have been implicated in the pathogenesis of a number of autoimmune diseases, and Yersinia enterocolitica (YE) might play a role in the development of autoimmune thyroid disease...Full Text Available

2003-05-01

307

Inactivation and Heat Stabilization of Poliovirus by 2-Thiouracil 1  

UK PubMed Central (United Kingdom)

Treatment of poliovirus Type I with 10−3m 2-thiouracil (2-TU) resulted in the inactivation of greater than 90% of the virus infectivity and stabilization of approximately...Full Text Available

1967-08-01

308

In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators  

UK PubMed Central (United Kingdom)

African trypanosomes exert significant morbidity and mortality in man and livestock. Only a few drugs are available for the treatment of trypanosome infections and therefore, the development of new...Full Text Available

309

Impact of Plasmodium falciparum infection on the frequency of moderate to severe anaemia in children below 10 years of age in Gabon  

UK PubMed Central (United Kingdom)

BackgroundImproving the understanding of childhood malarial anaemia may help in the design of appropriate management strategies.MethodsA...Full Text Available

310

Immune activation and IL-12 production during acute/early HIV infection in the absence and presence of highly active, antiretroviral therapy  

UK PubMed Central (United Kingdom)

Suppressed IL-12 production and maladaptive immune activation, both of which are ameliorated by successful highly active antiretroviral therapy (HAART), are thought to play important roles in the immunopathogenesis...Full Text Available

2008-12-01

311

Illthrift in Suckling Lambs Secondary to Umbilical Infections and Possible Implication of Cryptosporidiosis as a Risk Factor  

UK PubMed Central (United Kingdom)

Illthrift was observed in 20/60 lambs aged 40–45 days in a dairy sheep flock in Greece. Cryptosporidiosis had been diagnosed and successfully treated with halofuginone lactate a month earlier....Full Text Available

312

Identification of CTX-M-Type Extended-Spectrum-?-Lactamase Genes Using Real-Time PCR and Pyrosequencing?  

UK PubMed Central (United Kingdom)

CTX-M extended-spectrum β-lactamases (ESBLs) are increasingly prevalent worldwide among Escherichia coli bacteria, mostly in community-acquired urinary tract infections. Finding...Full Text Available

2007-01-01

313

Identification and characterization of plasmids from the western aster yellows mycoplasmalike organism.  

UK PubMed Central (United Kingdom)

Supercoiled double-stranded DNA molecules (plasmids) were isolated from plants infected with three laboratory strains of western aster yellows mycoplasma-like organism (AY-MLO) by using cesium chloride-ethidium...Full Text Available

1990-03-01

314

Identification and Characterization of CPS1 as a Hyaluronic Acid Synthase Contributing to the Pathogenesis of Cryptococcus neoformans Infection?  

UK PubMed Central (United Kingdom)

Cryptococcus neoformans is a pathogenic yeast that often causes devastating meningoencephalitis in immunocompromised individuals. We have previously identified the C. neoformans...Full Text Available

2007-08-01

315

INFLUENCE OF PERCEIVED SECONDARY STIGMA AND FAMILY ON THE RESPONSE TO HIV INFECTION AMONG INJECTION DRUG USERS IN VIETNAM  

UK PubMed Central (United Kingdom)

The full impact of secondary stigma (stigma directed at family) on an HIV-positive individual is unknown. This qualitative research explores perceptions of secondary stigma in the Vietnamese...Full Text Available

2010-12-01

316

Human spumaretrovirus-related sequences in the DNA of leukocytes from patients with Graves disease.  

UK PubMed Central (United Kingdom)

Viruses, and more particularly retroviruses, have been postulated to play a role in the pathogenesis of autoimmune diseases. In a search for spumaretrovirus infection markers, we screened a group of...Full Text Available

1992-11-01

317

Human bone matrix gelatin as a clinical alloimplant. A retrospective review of 160 cases.  

Science.gov (United States)

Bone matrix gelatin, prepared by sequential chemical treatment including decalcification with 0.6 N hydrochloric acid [9], was used as an alloimplant for the treatment of benign bone tumours, tumorous conditions of bone, acetabular dysplasia, delayed union, traumatic bone defects and other disorders. The bone matrix gelatin implanted into bone defects was incorporated successfully in 98% of implantations, excluding cases of infection, tumour recurrence and recurrence of tumorous conditions. The material was also implanted into ten bone sites as an onlay but in five it was resorbed without new bone formation. The incorporation of the bone matrix gelatin into the recipient bed was completed from 6 to 33 months (average 14.9 months) after implantation. Wound infection complicated 5 of 165 implantations (3%) in previously uninfected sites. Low grade fever persisting after the tenth post-operative day (a probable sign of immunological reaction) ...

1985-01-01

318

Helicobacter pylori infection, oncogenic pathways and epigenetic mechanisms in gastric carcinogenesis  

UK PubMed Central (United Kingdom)

Chronic colonization of the human stomach by Helicobacter pylori, a Gram-negative bacterium, is the major cause of chronic gastritis, peptic ulcers and gastric cancer. Recent...Full Text Available

2010-05-01

319

HIV prevention in prisons and jails: obstacles and opportunities.  

UK PubMed Central (United Kingdom)

High rates of human immunodeficiency virus (HIV) infection among jail and prison inmates suggest that HIV prevention efforts should focus on incarcerated populations. Overcrowding, the high prevalence...Full Text Available

1994-09-01

320

Gonorrhoea in men: clinical and diagnostic aspects.  

UK PubMed Central (United Kingdom)

AIM: To review the features of gonococcal infection in men in the 1990s. METHODS: A retrospective study of all men with gonorrhoea presenting to an inner city department of genitourinary medicine in...Full Text Available

1996-12-01

321

Genomic Expression Libraries for the Identification of Cross-Reactive Orthopoxvirus Antigens  

UK PubMed Central (United Kingdom)

Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young non-vaccinated persons have renewed interest in this zoonotic disease. Usually causing...Full Text Available

322

Genetic studies of fertility and pathogenicity in Magnaporthe grisea (Pyricularia oryzae)  

Energy Technology Data Exchange (ETDEWEB)

Crosses between field isolates of Magnaporthe grisea (anamorph, Pyricularia oryzae Cav. and Pyricularia grisea) have led to the development of fertile laboratory strains that infect goosegrass and/or weeping lovegrass. These strains may now be utilized in a rigorous genetic analysis of host species specificity and general pathogenicity. Attempts to improve the fertility of rice pathogens for the goal of undertaking a genetic analysis of host cultivar specificity have so far been unsuccessful. Crosses between M. grisea strains that infect rice, goosegrass or weeping lovegrass demonstrate that host species specificity differences between field isolates of this fungus in some cases have a complete genetic basis, and in other cases have a simple genetic basis. Crosses between a field isolate of the pathogen that infects weeping lovegrass and a field isolate that infects goosegrass have resulted in the ...

1984-01-01

323

Genetic heterogeneity in human T-cell leukemia/lymphoma virus type II.  

UK PubMed Central (United Kingdom)

DNA from the peripheral blood mononuclear cells of 17 different individuals infected with human T-cell lymphoma/leukemia virus type II (HTLV-II) was successfully amplified by the polymerase chain reaction...Full Text Available

1993-03-01

324

Genetic Evidence for Inhibition of Bacterial Division Protein FtsZ by Berberine  

UK PubMed Central (United Kingdom)

BackgroundBerberine is a plant alkaloid that is widely used as an anti-infective in traditional medicine. Escherichia coli exposed to berberine form filaments, suggesting...Full Text Available

325

Genetic Diversity in Blastomyces dermatitidis: Implications for PCR Detection in Clinical and Environmental Samples  

UK PubMed Central (United Kingdom)

SummaryBlastomycosis is a serious and potentially fatal infection by the thermally dimorphic fungus Blastomyces dermatitidis. PCR assays targeting the BAD-1 virulence...Full Text Available

2010-03-01

326

Gallium Disrupts Iron Uptake by Intracellular and Extracellular Francisella Strains and Exhibits Therapeutic Efficacy in a Murine Pulmonary Infection Model ?  

UK PubMed Central (United Kingdom)

Francisella tularensis requires iron (Fe) for growth, but the biologic sources of Fe for this organism are largely unknown. We found that Francisella sp. growing in...Full Text Available

2010-01-01

327

GROWTH REGULATION IN ROUS SARCOMA VIRUS INFECTED CHICKEN EMBRYO FIBROBLASTS: THE ROLE OF THE src GENE  

Energy Technology Data Exchange (ETDEWEB)

We report here a study of the mechanisms leading to loss of growth control in chicken embryo fibroblasts transformed by Rous sarcoma virus (RSV). We have been particularly concerned with the role of the src gene in this process, and have used RSV mutants temperature sensitive (ts) for transformation to investigate the nature of the growth regulatory lesion. The two principal findings were (1) the stationary phase of the cell cycle (G{sub 1}) in chick embryo fibroblasts seems to have two distinct regulatory compartments (using the terminology of Brooks et al. we refer to these as 'Q' and 'A' states). When rendered stationary at 41.5 C by serum deprivation, normal cells enter a Q state, but cells infected with the ts-mutant occupy an A state. (2) Whereas normal cells can occupy either state depending on culture conditions, the ts-infected cells, at 41.5 C, do not seem to enter Q even though a known src gene ...

1980-07-01

328

Fungal Infection in Patients with Serpiginous Choroiditis or Acute Zonal Occult Outer Retinopathy?  

UK PubMed Central (United Kingdom)

The etiologies of a number of retinopathies, including serpiginous choroiditis and acute zonal occult outer retinopathy (AZOOR), remain uncertain. Recently, we provided evidence that AZOOR is caused...Full Text Available

2008-01-01

329

Fluorescence amplified fragment length polymorphism for subtyping of genotypes of Acanthamoeba isolated from patients with keratitis  

UK PubMed Central (United Kingdom)

Background & objectives:Acanthamoeba keratitis (AK) is a painful and vision-threatening ocular infection. The differentiation of Acanthamoeba...Full Text Available

2011-01-01

330

Flock infection and transport as sources of salmonellae in broiler chickens and carcasses.  

UK PubMed Central (United Kingdom)

Cultural monitoring was used to determine the incidence and sources of salmonellae in a 4160-bird broiler flock raised on litter in 32 pens. Twenty-five of the pens remained apparently free of salmonellae...Full Text Available

1980-07-01

331

Five year prospective study of plasma renin activity and blood pressure in patients with longstanding reflux nephropathy.  

UK PubMed Central (United Kingdom)

Eight of 100 normotensive children who had pyelonephritic scarring secondary to urinary infection and vesicoureteric reflux were found in an earlier study to have increased plasma renin activity (PRA)....Full Text Available

1987-07-01

332

First Culture Isolation of Borrelia lonestari, Putative Agent of Southern Tick-Associated Rash Illness  

UK PubMed Central (United Kingdom)

Southern tick-associated rash illness (STARI) is a Lyme disease-like infection described in patients in the southeastern and south-central United States, where classic Lyme disease is relatively rare....Full Text Available

2004-03-01

333

Field application of a colorimetric method of assaying chloroquine and desethylchloroquine in urine  

UK PubMed Central (United Kingdom)

In a study in western Kenya of malaria-infected adult women who had been treated with chloroquine, we compared the level of chloroquine and its principal metabolite, desethylchloroquine, in urine,...Full Text Available

1988-01-01

334

Factors Predicting and Reducing Mortality in Patients with Invasive Staphylococcus aureus Disease in a Developing Country  

UK PubMed Central (United Kingdom)

BackgroundInvasive Staphylococcus aureus infection is increasingly recognised as an important cause of serious sepsis across the developing world, with mortality...Full Text Available

335

Expression of SV40 virus large T antigen by recombinant adenoviruses activates proliferation of corneal endothelium in vitro.  

UK PubMed Central (United Kingdom)

Infection with the Ad5-SVR4 virus was used to introduce the large T antigen encoding region of the SV40 virus into bovine and human corneal endothelial cells. Expression of large T antigen occurred...Full Text Available

1993-04-01

336

Experimental avian paramyxovirus serotype-3 infection in chickens and turkeys  

UK PubMed Central (United Kingdom)

Avian paramyxoviruses (APMV) are divided into nine serotypes. Newcastle disease virus (APMV-1) is the most extensively characterized, while relatively little information is available for the other APMV...Full Text Available

2010-09-01

337

Exotic Small Mammals as Potential Reservoirs of Zoonotic Bartonella spp.  

UK PubMed Central (United Kingdom)

To evaluate the risk for emerging human infections caused by zoonotic Bartonella spp. from exotic small mammals, we investigated the prevalence of Bartonella spp. in...Full Text Available

2009-04-01

338

Evidence of an inflammatory-like response in non-normally pigmented tissues of two scleractinian corals  

UK PubMed Central (United Kingdom)

Increasing evidence of links between climate change, anthropogenic stress and coral disease underscores the importance of understanding the mechanisms by which reef-building corals resist infection...Full Text Available

2008-12-07

339

Evaluation of two commercial jet nebulisers and three compressors for the nebulisation of antibiotics.  

UK PubMed Central (United Kingdom)

Nebulised antibiotics have been shown to be beneficial in the treatment of lung infections in cystic fibrosis. Studies on the efficiency of nebuliser systems are constantly required in view of the large...Full Text Available

1994-10-01

340

Evaluation of the OptiMAL Test for Rapid Diagnosis of Plasmodium vivax and Plasmodium falciparum Malaria  

UK PubMed Central (United Kingdom)

The development of rapid and specific diagnostic tests to identify individuals infected with malaria is of paramount importance in efforts to control the severe public health impact of this disease....Full Text Available

1998-01-01

341

Entry and release of transmissible gastroenteritis coronavirus are restricted to apical surfaces of polarized epithelial cells.  

UK PubMed Central (United Kingdom)

The transmissible gastroenteritis coronavirus (TGEV) infects the epithelial cells of the intestinal tract of pigs, resulting in a high mortality rate in piglets. This study shows the interaction of...Full Text Available

1994-12-01

342

Elucidation of the Pharmacokinetic/Pharmacodynamic Determinant of Colistin Activity against Pseudomonas aeruginosa in Murine Thigh and Lung Infection Models?  

UK PubMed Central (United Kingdom)

Colistin is increasingly used as last-line therapy against Gram-negative pathogens. The pharmacokinetic (PK)/pharmacodynamic (PD) index that best correlates with the efficacy of colistin remains undefined....Full Text Available

2010-03-01

343

Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus  

UK PubMed Central (United Kingdom)

One-third of botanical remedies from southern Italy are used to treat skin and soft tissue infection (SSTI). Staphylococcus aureus, a common cause of SSTI, has generated increasing...Full Text Available

2008-08-13

344

Effect of precalving intramammary treatment with pirlimycin in nulliparous Holstein heifers  

UK PubMed Central (United Kingdom)

A clinical trial was conducted to determine whether prepartum intramammary pirlimycin reduces the proportion of nulliparous heifers with intramammary infection (IMI) during early lactation and improves...Full Text Available

2007-10-01

345

Effect of clindamycin on neutrophil killing of gram-negative periodontal bacteria.  

UK PubMed Central (United Kingdom)

Periodontal diseases are infections of the tissues supporting the dentition. Recognition that relatively specific microfloras are associated with distinct clinical forms of periodontal disease has prompted...Full Text Available

1988-10-01

346

Effect of a mixture of micronutrients, but not of bovine colostrum concentrate, on immune function parameters in healthy volunteers: a randomized placebo-controlled study  

UK PubMed Central (United Kingdom)

BackgroundSupplementation of nutritional deficiencies helps to improve immune function and resistance to infections in malnourished subjects. However, the suggested benefits of dietary...Full Text Available

347

Diterpene Biosynthesis in Maize Seedlings in Response to Fungal Infection 1  

UK PubMed Central (United Kingdom)

A cell-free system which catalyzes the biosynthesis of terpene hydrocarbons when supplemented with mevalonate, Mn2+, and ATP was prepared from the scutellum-embryonic axis region of maize...Full Text Available

1979-09-01

348

Distribution Frequency of Pathogenic Bacteria Isolated from Cutaneus Leishmaniasis Lesions  

UK PubMed Central (United Kingdom)

Cutaneous leishmaniasis (CL) is a parasitic disease characterized by single or multiple ulcerations. Secondary bacterial infections are one of the complications that can increase the tissue destruction...Full Text Available

2008-09-01

349

Differential recognition of viral RNA by RIG-I  

UK PubMed Central (United Kingdom)

Retinoic acid inducible gene I (RIG-I) is a pattern recognition receptor (PRR) responsible for detection of nucleic acids from pathogens in the cytoplasm of infected cells and induction of type I interferon...Full Text Available

2011-03-01

350

Diagnostic comparison of malaria infection in peripheral blood, placental blood and placental biopsies in Cameroonian parturient women  

UK PubMed Central (United Kingdom)

BackgroundIn sub-Saharan Africa, Plasmodium falciparum malaria in pregnancy presents an enormous diagnostic challenge. The epidemiological and clinical relevance...Full Text Available

351

Determinants of antiviral treatment initiation in a hepatitis C-infected population benefiting from universal health care coverage  

UK PubMed Central (United Kingdom)

BACKGROUND AND AIMS:In view of increasing therapeutic efficacy, the delivery of hepatitis C virus (HCV) antiviral treatment is expected to increase. Yet practical experience reveals...Full Text Available

2007-06-01

352

Detection of hepatitis B virus DNA among accepted blood donors in Nanjing, China  

UK PubMed Central (United Kingdom)

BackgroundPosttransfusion hepatitis B virus (HBV) infection still occurs although its incidence has been substantially reduced since the introduction of screening of hepatitis B...Full Text Available

353

Detection of Sub-Clinical CWD Infection in Conventional Test-Negative Deer Long after Oral Exposure to Urine and Feces from CWD+ Deer  

UK PubMed Central (United Kingdom)

BackgroundChronic wasting disease (CWD) of cervids is a prion disease distinguished by high levels of transmissibility, wherein bodily fluids and excretions are thought to play an...Full Text Available

354

Defining and measuring the costs of the HIV epidemic to business firms.  

UK PubMed Central (United Kingdom)

Most published estimates of the costs of the epidemic of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) have been developed from the societal perspective,...Full Text Available

1994-05-01

355

Defective hepatitis B virus particles are generated by packaging and reverse transcription of spliced viral RNAs in vivo.  

UK PubMed Central (United Kingdom)

Generation of replicative defective viruses is frequently observed during viral infections. We now report that encapsidation and reverse transcription of spliced viral RNA is an additional mechanism...Full Text Available

1991-10-01

356

Current status of a hepatitis C vaccine: encouraging results but significant challenges ahead  

DEFF Research Database (Denmark)

Persistent hepatitis C virus (HCV) infection affects 170 million people worldwide. Acute HCV infection is often asymptomatic, but many infected individuals develop persistent infections that may lead to development of end-stage liver diseases, including liver cirrhosis and hepatocellular carcinoma. Thus, an HCV vaccine that could significantly lower the chronicity rate would have a major impact on the disease burden. Unfortunately, HCV is a highly mutable virus, and escape mutations can undermine vaccine-induced virus-specific immunity. Also, HCV exists as multiple genotypes, and so genotype-specific vaccines might be required to achieve broad protection. Finally, vaccine development has been hampered by the lack of a small animal model and cell culture systems, but these are currently being established. Despite these obstacles, several vaccine candidates tested in the chimpanzee HCV model have shown ...

2007-01-01

357

Coping with crowds: Density-dependent disease resistance in desert locusts  

UK PubMed Central (United Kingdom)

Parasite transmission generally exhibits some form of positive density dependence. Thus, as population density increases, so too does the per capita risk of becoming infected. Under...Full Text Available

2002-04-16

358

Consequences of unlocking the cardiac myosin molecule in human myocarditis and cardiomyopathies  

UK PubMed Central (United Kingdom)

Myocarditis, often initiated by viral infection, may progress to autoimmune inflammatory heart disease, dilated cardiomyopathy and heart failure. Although cardiac myosin is a dominant autoantigen...Full Text Available

2008-09-01

359

Complexes of hepatitis B surface antigen and immunoglobulin M in the sera of patients with hepatitis B virus infection.  

UK PubMed Central (United Kingdom)

Hepatitis B surface antigen (HBsAg) bound to immunoglobulin M (IgM) was detected in sera of HBsAg carriers by a radioimmunoassay based on selective absorption of the immunoglobulin on a solid phase...Full Text Available

1983-09-01

360

Complement Factor H-Related Proteins CFHR2 and CFHR5 Represent Novel Ligands for the Infection-Associated CRASP Proteins of Borrelia burgdorferi  

UK PubMed Central (United Kingdom)

BackgroundOne virulence property of Borrelia burgdorferi is its resistance to innate immunity, in particular to complement-mediated killing. Serum-resistant B....Full Text Available

361

Comparison of geographical strains of Schistosoma mansoni in the rhesus monkey*  

UK PubMed Central (United Kingdom)

Rhesus monkeys were infected with strains of Schistosoma mansoni from Puerto Rico, St Lucia, Brazil, and Tanzania. Monkeys were killed 11-14 weeks after exposure to 600-650 cercariae....Full Text Available

1972-01-01

362

Comparison of geographical strains of Schistosoma mansoni in the mouse*  

UK PubMed Central (United Kingdom)

Mice were killed 7, 11, 19, and 27 weeks after infection with strains of Schistosoma mansoni from Puerto Rico, Brazil, St Lucia, and Tanzania. The percentage recovery of adult worms...Full Text Available

1972-01-01

363

Comparison of azlocillin, ceftizoxime, cefoxitin, and amikacin alone and in combination against Pseudomonas aeruginosa in a neutropenic-site rabbit model.  

UK PubMed Central (United Kingdom)

The efficacy of beta-lactam antibiotics and amikacin alone and in various combinations against Pseudomonas aeruginosa was studied in a rabbit model simulating a closed-space infection in a locally neutropenic...Full Text Available

1984-05-01

364

Comparative analysis of differentially expressed genes in normal and white spot syndrome virus infected Penaeus monodon  

UK PubMed Central (United Kingdom)

BackgroundWhite spot syndrome (WSS) is a viral disease that affects most of the commercially important shrimps and causes serious economic losses to the shrimp farming industry worldwide....Full Text Available

365

Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria  

UK PubMed Central (United Kingdom)

There is growing epidemiological and molecular evidence that ABO blood group affects host susceptibility to severe Plasmodium falciparum infection. The high frequency of common...Full Text Available

2008-02-15

366

Clostridium difficile is not associated with outbreaks of viral gastroenteritis in the elderly in the Netherlands  

UK PubMed Central (United Kingdom)

The coincidental increase in norovirus outbreaks and Clostridium difficile infection (CDI) raised the question of whether these events could be related, e.g. by enhancing spread by...Full Text Available

2010-06-01

367

Clinical perspective on aztreonam lysine for inhalation in patients with cystic fibrosis  

UK PubMed Central (United Kingdom)

Progressive obstructive lung disease is a characteristic component of cystic fibrosis (CF). It is the pulmonary manifestations, including obstruction and endobronchial infection, which directly contribute...Full Text Available

368

Chlamydia trachomatis Load at Matched Anatomic Sites: Implications for Screening Strategies?  

UK PubMed Central (United Kingdom)

Urethral and endocervical swabs and self-collected vaginal swabs (SCVSs) and urine specimens are all used as samples for diagnosis of urogenital infection with Chlamydia trachomatis....Full Text Available

2007-05-01

369

Characterization of the 5'-terminal cap structures of early simian virus 40 mRNA.  

UK PubMed Central (United Kingdom)

Early simian virus 40-specific mRNA was isolated from lytically infected and stably transformed cells and analyzed with respect to the 5'-terminal cap content. An analogous diversity of capped structures...Full Text Available

1980-09-01

370

Characterization of a fatty acid and retinol binding protein orthologue from the hookworm Ancylostoma ceylanicum?  

UK PubMed Central (United Kingdom)

Hookworms, bloodfeeding intestinal nematodes, infect nearly one billion people in resource limited countries and are a leading cause of anemia and malnutrition. Like other nematodes, hookworms...Full Text Available

2009-12-01

371

Breast cancer and human papillomavirus infection: No evidence of HPV etiology of breast cancer in Indian women  

UK PubMed Central (United Kingdom)

BackgroundTwo clinically relevant high-risk HPV (HR-HPV) types 16 and 18 are etiologically associated with the development of cervical carcinoma and are also reported to be present...Full Text Available

372

Breaking the 1000-gene barrier for Mimivirus using ultra-deep genome and transcriptome sequencing  

UK PubMed Central (United Kingdom)

BackgroundMimivirus, a giant dsDNA virus infecting Acanthamoeba, is the prototype of the mimiviridae family, the latest addition to the family of the nucleocytoplasmic...Full Text Available

373

Bacterial lipopolysaccharide induces an endocrine switch from prostaglandin F2? to prostaglandin E2 in bovine endometrium  

UK PubMed Central (United Kingdom)

Escherichia coli infection of the endometrium causes uterine disease after parturition and is associated with prolonged luteal phases of the ovarian cycle in cattle. Termination...Full Text Available

2009-04-01

374

Bacterial infections in suspected cutaneous leishmaniasis lesions.  

UK PubMed Central (United Kingdom)

In Iran, microscopic examination of skin scrapings from 2202 individuals with clinically diagnosed cutaneous leishmaniasis (CL) lesions revealed the presence of amastigotes in 1123 cases (51.0%). Bacteriological...Full Text Available

1990-01-01

375

Bacteraemia during prostatectomy and other transurethral operations: influence of timing of antibiotic administration.  

UK PubMed Central (United Kingdom)

The relation between the timing of prophylactic antibiotic administration and the occurrence of bacteraemia during transurethral operations was studied in 112 patients whose urine was infected before...Full Text Available

1984-06-01

376

Apoptosis induced by parasitic diseases  

UK PubMed Central (United Kingdom)

Fatalities caused by parasitic infections often occur as a result of tissue injury that results from a form of host-cell death known as apoptosis. However, instead of being pathogenic, parasite-induced...Full Text Available

377

Antiviral Inhibition of Enveloped Virus Release by Tetherin/BST-2: Action and Counteraction  

UK PubMed Central (United Kingdom)

Tetherin (BST2/CD317) has been recently recognized as a potent interferon-induced antiviral molecule that inhibits the release of diverse mammalian enveloped virus particles from infected cells. By...Full Text Available

378

Antimalarial activities and subacute toxicity of RC-12, a 4-amino-substituted pyrocatechol.  

UK PubMed Central (United Kingdom)

RC-12 [1,2-dimethoxy-4-(bis-diethylaminoethyl)-amino-5-bromobenzene] was evaluated for prophylactic, radical curative, and suppressive activities against infections with Plasmodium cynomolgi and subacute...Full Text Available

1985-11-01

379

Anti-Apoptotic Genes in the Survival of Monocytic Cells During Infection  

UK PubMed Central (United Kingdom)

Macrophages are cells of the immune system that protect organisms against invading pathogens by fulfilling critical roles in innate and adaptive immunity and inflammation. They originate from circulating...Full Text Available

2009-08-01

380

Antagonist HIV-1 Gag Peptides Induce Structural Changes in HLA B8  

UK PubMed Central (United Kingdom)

In the cellular immune response, recognition by CTL-TCRs of viral antigens presented as peptides by HLA class I molecules, triggers destruction of the virally infected cell (Townsend, A.R.M., J. Rothbard,...Full Text Available

1996-12-01

381

Age-Stratified Bayesian Analysis To Estimate Sensitivity and Specificity of Four Diagnostic Tests for Detection of Cryptosporidium Oocysts in Neonatal Calves?  

UK PubMed Central (United Kingdom)

There is no gold standard diagnostic test for the detection of bovine cryptosporidiosis. Infection is usually highest in 2-week-old calves, and these calves also excrete high numbers of oocysts. These...Full Text Available

2011-01-01

382

Absence of detectable xenotropic murine leukemia virus-related virus in plasma or peripheral blood mononuclear cells of human immunodeficiency virus Type 1-infected blood donors or individuals in Africa  

British Library Electronic Table of Contents (United Kingdom)

BACKGROUND: Since the identification of xenotropic murine leukemia virus-related virus (XMRV) in prostate cancer patients in 2006 and in chronic fatigue syndrome patients in 2009, conflicting findings have been reported regarding its etiologic role in human diseases and prevalence in general populations. In this study, we screened both plasma and peripheral blood mononuclear cells (PBMNCs) collected in Africa from blood donors and human immunodeficiency virus Type 1 (HIV-1)-infected individuals to gain evidence of XMRV infection in this geographic region. STUDY DESIGN AND METHODS: A total of 199 plasma samples, 19 PBMNC samples, and 50 culture supernatants from PBMNCs of blood donors from Cameroon found to be infected with HIV-1 and HIV-1 patients from Uganda were screened for XMRV infecti...

2011-01-01

383

A small RNA promotes siderophore production through transcriptional and metabolic remodeling  

UK PubMed Central (United Kingdom)

Siderophores are essential factors for iron (Fe) acquisition in bacteria during colonization and infection of eukaryotic hosts, which restrain iron access through iron-binding protein, such as lactoferrin...Full Text Available

2010-08-24

384

A report of clinical trial conducted on Toto ointment and soap products.  

UK PubMed Central (United Kingdom)

OBJECTIVE: The efficacy of Toto ointment and soap on common skin disorders was tested. METHODOLOGY: A cohort of Nigerians with common skin conditions such as fungal and bacterial skin infections, scabies,...Full Text Available

2003-01-01

385

A cross-sectional study of Tritrichomonas foetus infection among healthy cats at shows in Norway  

UK PubMed Central (United Kingdom)

BackgroundIn recent years, the protozoan Tritrichomonas foetus has been recognised as an important cause of chronic large-bowel diarrhoea in purebred cats in many...Full Text Available

386

A Strong Case for Viral Genetic Factors in HIV Virulence  

UK PubMed Central (United Kingdom)

HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four...Full Text Available

387

A Serological Survey of Sera from Domestic Animals on Easter Island  

UK PubMed Central (United Kingdom)

Animals' sera collected on Easter Island from December 1964 to February 1965 were tested by appropriate methods for the presence of antibodies to various infections. These included, ornithosis, Q-fever,...Full Text Available

1968-04-01

388

A Rapid Murine Coma and Behavior Scale for Quantitative Assessment of Murine Cerebral Malaria  

UK PubMed Central (United Kingdom)

BackgroundCerebral malaria (CM) is a neurological syndrome that includes coma and seizures following malaria parasite infection. The pathophysiology is not fully understood and cannot...Full Text Available

389

A Point Mutation in a Domain of Gamma Interferon Receptor 1 Provokes Severe Immunodeficiency  

UK PubMed Central (United Kingdom)

Gamma interferon (IFN-γ) and the cellular responses induced by it are essential for controlling mycobacterial infections. Most patients bearing an IFN-γ receptor ligand-binding chain...Full Text Available

2001-01-01

390

A Dominant Role for the Immunoproteasome in CD8+ T Cell Responses to Murine Cytomegalovirus  

UK PubMed Central (United Kingdom)

Murine cytomegalovirus (MCMV) is an important animal model of human cytomegalovirus (HCMV), a β-Herpesvirus that infects the majority of the world's population and causes disease in neonates...Full Text Available

391

A Case of Neurocysticercosis in Entire Spinal Level  

UK PubMed Central (United Kingdom)

Cysticercosis is the most common parasitic infection affecting the central nervous system. Spinal neurocysticercosis (NCC) is very rare compared with intracranial NCC and requires more aggressive management...Full Text Available

2010-10-01

392

The Immunity-related GTPase Irgm3 Relieves Endoplasmic Reticulum Stress Response during Coxsackievirus B3 Infection via a PI3K/Akt Dependent Pathway.  

Science.gov (United States)

The IRG protein Irgm3 preserves cell survival during coxsackievirus B3 (CVB3) infection. However, the molecular mechanisms are not clear. Here, we examined the effect of Irgm3 expression on ER stress triggered by pharmacological agents or CVB3 infection. In Tet-On/Irgm3 HeLa cells, Irgm3 expression suppressed either chemical- or CVB3-induced upregulation of glucose-regulated protein78. Further, Irgm3 strongly inhibited the activation of both the PERK and ATF6 pathways of ER stress responses, which further led to the diminished phosphorylation of eIF2?, reduced cleavage/activation of transcription factor SREBP1 and attenuated induction of proapoptotic genes CHOP and GADD34. These data were further supported by experiments using Irgm3 knockout mouse embryonic fibroblasts, in which the ER stress induced by CVB3 was not relieved due to the lack of Irgm3 expression. In addition, the tunicamycin-triggered ER stress promoted the subsequent CVB3 ...

2011-10-10

393

Characterization of monocyte differentiation-inducing (MDI) factors derived from human fetal membrane chorion cells undergoing apoptosis after influenza virus infection.  

Science.gov (United States)

Influenza virus infection during pregnancy has been implicated as one of cause of premature delivery, abortion and stillbirth. We have reported that cultured human fetal membrane chorion cells undergoing apoptosis by influenza virus infection secrete unidentified heat-stable monocyte differentiation-inducing (MDI) factors. In this study, cellular, biological and immunochemical characteristics of MDI factors were investigated using human monocytic leukemia THP-1 cells by nitroblue tetrazolium reduction and cell adhesion assays. The treatment of THP-1 cells with culture supernatants from the influenza virus-infected chorion cells induced the nitroblue tetrazolium reduction ability, which was inhibited by the addition of superoxide dismutase and diphenyleneiodonium chloride, an inhibitor for reduced nicotinamide adenine dinucleotide phosphate oxidase. The phenomenon was also observed in human peripheral blood monocytes and ...

2006-06-06

394

The dosimetric verification of a pencil beam based treatment planning system  

International Nuclear Information System (INIS)

A new three-dimensional treatment planning system (TPS) based on convolution/superposition algorithms (TMS-Radix from HELAX AB, Uppsala, Sweden) was recently installed at the University Hospital in Lund. The purpose of the present study was to design a quality assurance and acceptance testing programme to meet the specific characteristics of this convolution model. The model is based on parametrization of a non-measurable quantity - the polyenergetic pencil beam. However, the verification of the treatment planning model is still dependent on numerous comparisons of measured depth-doses and dose profiles. The test programme was divided in two basic parts: (i) model implementation and beam data consistency and (ii) model performance and limitations in special situations. The first part was scheduled for all photon beam qualities available before they could be used for clinical treatment planning. The second part was performed for selected energies only. The results ...

395

Technological advances and applications of geothermal energy pile foundations and their feasibility in Australia  

Energy Technology Data Exchange (ETDEWEB)

Geothermal energy pile foundations are an alternative energy source for heating and cooling needs. Utilising this source of energy has great potential due to the environmental, economic and social benefits. This paper looks at an extensive amount of literature on the technology behind the system including the overall process, primary considerations for each of the main components including latest developments as well as design implications such as the integration of ground energy systems into structural piles of buildings. Environmental considerations including performance-dependent parameters of the subsurface are described. Main parameters include thermal conductivity, thermal diffusivity, specific heat capacity and moisture content. Temperature and groundwater effects are also discussed and design considerations are provided. Mathematical models are available to aid in the design of these systems but there are various other issues and complex parameters that need to be considered ...

2010-12-15

396

Substance Flow Analyses of Organic Pollutants in Stockholm  

International Nuclear Information System (INIS)

This paper summarizes substance flow analyses for four organic substances in the City of Stockholm, Sweden: diethylhexyl phthalate (DEHP), alkylphenolethoxylates (APEO), polybrominated diphenylethers (PBDE) and chlorinated paraffins (CP). The results indicate that the stocks of APEO, PBDE and CP all are approximately 200-250 tonnes, whereas the DEHP stock is two orders of magnitude larger. Emissions can be linked to imported consumer goods such as electronics (PBDE) and textiles (APEO), and to construction materials (DEHP, CP). For several of the substances considerable amounts remain in the technosphere for a long time, even after use of the substance in new products has been eliminated. For example, the use of DEHP as plasticizer for PVC plastics in cables and floorings has more or less been phased-out, but still these applications make up a stock of some 20,000 tonnes (85% of the total DEHP stock in Stockholm) and emit 28 tonnes of DEHP annually (93% of overall ...

2008-12-01

397

Status of non-electric nuclear heat applications: Technology and safety  

International Nuclear Information System (INIS)

Nuclear energy plays an important role in electricity generation, producing 16% of the world's electricity at the beginning of 1999. It has proven to be safe, reliable, economical and has only a minimal impact on the environment. Most of the world's energy consumption, however, is in the form of heat. The market potential for nuclear heat was recognized early. Some of the first reactors were used for heat supply, e.g. Calder Hall (United Kingdom), Obninsk (Russian Federation), and Agesta (Sweden). Now, over 60 reactors are supplying heat for district heating, industrial processes and seawater desalination. But the nuclear option could be better deployed if it would provide a larger share of the heat market. In particular, seawater desalination using nuclear heat is of increasing interest to some IAEA Member States. In consideration of the growing experience being accumulated, the IAEA periodically reviews the progress and new developments in the field of nuclear ...

398

Recent developments in the way forward for alternative methods: Formation of national consensus platforms in Europe  

Science.gov (United States)

Ecopa, the European Consensus Platform on 3R-Alternatives, is an international not-for-profit organization that wants to stimulate the development of 3R-alternatives, increase awareness among the public, scientists and regulatory bodies, and help their implementation into the different national legislations. This is done by networking and bringing together National Consensus Platforms on 3R-alternatives. Consensus means that all parties concerned are represented, namely, animal welfare, industry, academia, and governmental institutions. Actually, 14 Member State Platforms exist. Fully complying with the criteria, set by ecopa, are the platforms of Austria, Belgium, the Czech Republic, Finland, Germany, Italy, the Netherlands, Spain, Sweden, Switzerland, and the United Kingdom. Under development are the platforms of Denmark, Norway, and Poland. To reach its goals, ecopa uses conventional scientific tools such as workshops and meetings but it also makes ...

2005-09-01

399

Medium term evaluation of meteorological conditions, power performance and loads on the first Swedish offshore wind farm at Bockstigen  

Energy Technology Data Exchange (ETDEWEB)

The first offshore wind farm in Sweden; Bockstigen, consists of five 500 kW stall controlled wind turbines on mono pile foundations. The main objectives of the technical evaluation are to verify the original design assumptions made for a load carrying mono pile and bedrock, investigate offshore power production versus onshore ditto as well as to determine park effects and analyse meteorological multi-mast statistics which serve as reference data to a newly developed computer code for offshore wind energy potential mapping. The 'main' measurement system has continuously been acquiring data at 1 and 20 Hz/channel since the summer of 1998. A 40 m meteorological mast was built within the wind farm in the summer of 1999 in order to acquire relatively undisturbed wind speed data from 'free' sectors as well as to enable wake measurements. The mono pile and tower of one of the turbines are equipped with strain gauges at several depths ...

2001-12-01

400

Emission characterization of an alcohol/diesel-pilot fueled compression-ignition engine and its heavy-duty diesel counterpart. Final report, August 1980-August 1981  

Energy Technology Data Exchange (ETDEWEB)

This report describes results from emissions testing of a prototype diesel engine, developed by Volvo Truck Corporation of Sweden, which uses pilot injection of diesel fuel for compression ignition of alcohol fuel injection for main combustion. In addition to this dual-fuel engine, emission testing was also conducted on a heavy-duty diesel engine of similar design. Both engines were tested over the 1979 13-mode FTP, or shorter versions of this modal test, and over the 1984 Transient FTP as well as an experimental bus cycle. The dual-fuel engine was characterized with methanol, ethanol and ethanol with 30 percent water (wt %). An oxidation catalyst was also used with methanol and ethanol. Emission characterization included regulated emissions (HC, CO, and NOX) along with total particulate, unburned alcohols, individual hydrocarbons, aldehydes, phenols, and odor. The particulate matter was characterized in terms of particle size distribution, sulfate content, C, H, ...

1981-08-01

401

Divergent views on a possible nuclear waste repository in the community: Social aspects of decision making  

Energy Technology Data Exchange (ETDEWEB)

The paper summarizes the results obtained in two interview studies conducted in the communities of Storuman and Malaa in northern Sweden, 1995 and 1997. It highlights the similarities and differences with respect to the public participation and decision processes which preceded the respective referenda in the two communities. The presentation includes the arguments used by proponents and opponents, the changes over time, as well as the time frame and the information involved in the processes. It is concluded e.g. that local cultures, life-styles, knowledge of similar events, and the time for and management of the participation process are important and salient factors in the resulting social dynamics. Factors of possibly more fundamental importance were also discerned, however, including overall attitude to and valuation of nuclear power, perceptions of development, solidarity, power and power distribution in relation to current as well as future situations. It is ...

1999-12-01

402

Consumer choice and suggested price for pork as influenced by its appearance, taste and information concerning country of origin and organic pig production  

DEFF Research Database (Denmark)

Reactions of consumers to the appearance and taste of pork with and without information concerning outdoor production of pigs were tested in France, Denmark, Sweden and UK. Consumers in all four countries focussed on colour and fatness rather than marbling and drip to make their choice. Almost half of the British and Danish preferred the paler and the French the darker pork. Most people preferred the leaner pork. When information was provided in the form of labels, the vast majority of consumers preferred the pork labelled as originating from their own country as opposed to 'imported' and that labelled as pork from pigs 'raised outside' as opposed to 'inside'. There was no difference in the taste of grilled pork from indoor and outdoor production systems but pork labelled 'home produced' or 'outdoor' were more appreciated. Consumers' willingness to pay varied widely and was higher for those consumers who found more of the characteristics they sought. Consumers ...

2005-01-01

403

Beam Test of a Prototype Detector Array for the PoGO Astronomical Hard X-Ray/Soft Gamma-Ray Polarimeter  

CERN Document Server

Polarization measurements in the X-ray and gamma-ray energy range can provide crucial information on massive compact objects such as black holes and neutron stars. The Polarized Gamma-ray Observer (PoGO) is a new balloon-borne instrument designed to measure polarization from astrophysical objects in the 30-100 keV range, under development by an international collaboration with members from United States, Japan, Sweden and France. To examine PoGO's capability, a beam test of a simplified prototype detector array was conducted at the Argonne National Laboratory Advanced Photon Source. The detector array consisted of seven plastic scintillators, and was irradiated by polarized photon beams at 60, 73, and 83 keV. The data showed a clear polarization signal, with a measured modulation factor of $0.42 \\pm 0.01$. This was successfully reproduced at the 10% level by the computer simulation package Geant4 after modifications to its implementation of polarized ...

2005-01-01

404

Automatic Gamma-Scanning System for Measurement of Residual Heat in Spent Nuclear Fuel  

International Nuclear Information System (INIS)

In Sweden, spent nuclear fuel will be encapsulated and placed in a deep geological repository. In this procedure, reliable and accurate spent fuel data such as discharge burnup, cooling time and residual heat must be available. The gamma scanning method was proposed in earlier work as a fast and reliable method for the experimental determination of such spent fuel data. This thesis is focused on the recent achievements in the development of a pilot gamma scanning system and its application in measuring spent fuel residual heat. The achievements include the development of dedicated spectroscopic data-acquisition and analysis software and the use of a specially designed calorimeter for calibrating the gamma scanning system. The pilot system is described, including an evaluation of the performance of the spectrum analysis software. Also described are the gamma-scanning measurements on 31 spent PWR fuel assemblies performed using the pilot system. The results obtained ...

405

Automatic Gamma-Scanning System for Measurement of Residual Heat in Spent Nuclear Fuel  

Energy Technology Data Exchange (ETDEWEB)

In Sweden, spent nuclear fuel will be encapsulated and placed in a deep geological repository. In this procedure, reliable and accurate spent fuel data such as discharge burnup, cooling time and residual heat must be available. The gamma scanning method was proposed in earlier work as a fast and reliable method for the experimental determination of such spent fuel data. This thesis is focused on the recent achievements in the development of a pilot gamma scanning system and its application in measuring spent fuel residual heat. The achievements include the development of dedicated spectroscopic data-acquisition and analysis software and the use of a specially designed calorimeter for calibrating the gamma scanning system. The pilot system is described, including an evaluation of the performance of the spectrum analysis software. Also described are the gamma-scanning measurements on 31 spent PWR fuel assemblies performed using the pilot system. The results obtained ...

2007-03-15

406

Analysis of international efforts in energy research and development  

Energy Technology Data Exchange (ETDEWEB)

Research and experimental development comprise innovative and creative work undertaken systematically to increase the stock of knowledge of science, engineering, and society. This knowledge reserve is used to improve living conditions and standards, including economic growth. Research and development (R&D) expenditures are useful measures of the scale and direction of technological innovation within a country, industry, or scientific field. Administrators concerned with economic growth and performance rely on R&D statistics as one possible type of indicator of technological change. R&D statistics are an essential tool in many government programs and evaluations (OECD 1993). The objective of the analysis was to identify and evaluate R&D funding sources, levels, and trends in the energy sectors of selected industrialized countries (Australia, Belgium, Canada, Denmark, Finland, France, Germany, Italy, Japan, Netherlands, Norway, Sweden, Switzerland, ...

1995-09-01

407

A food basket investigation during the autumn of 1994; Matkorgsundersoekning hoesten 1994  

Energy Technology Data Exchange (ETDEWEB)

During the autumn of 1994 an investigation of foodstuffs has been accomplished to assess the average intake of {sup 137}Cs by the Swedish population due to the Chernobyl accident. A standardized food basket has been collected from two grocers in 10 localities, of which the majority came from areas with the highest fallout. The estimated maximum intake of {sup 137}Cs was 815 Bq/year in the inland of the county of Vaesterbotten. The population weighted average intake for the fallout affected counties was 435 Bq/year. The rest of the county received an intake of 235 Bq/year. The population weighted average of the intake for the whole county was estimated to 274 Bq/year. From this intake the calculated body burden would be 1.3 Bq/kg for the average citizen. Whole-body measurements of a sample of the population gave 2.0 Bq/kg. A plausible explanation would be that 40% of the intake of {sup 137}Cs can have its origin from the 10% of the consumption of foodstuffs that are home produced or ...

1995-10-01

408

Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection.  

Science.gov (United States)

African bovine trypanosomiasis caused by Trypanosoma sp., is a major constraint on cattle productivity in sub-Saharan Africa. Some African Bos taurus breeds are highly tolerant of infection, but the potentially more productive Bos indicus zebu breeds are much more susceptible. Zebu cattle are well adapted for plowing and haulage, and increasing their tolerance of trypanosomiasis could have a major impact on crop cultivation as well as dairy and beef production. We used three strategies to obtain short lists of candidate genes within QTL that were previously shown to regulate response to infection. We analyzed the transcriptomes of trypanotolerant N'Dama and susceptible Boran cattle after infection with Trypanosoma congolense. We sequenced EST libraries from these two breeds to identify polymorphisms that might underlie previously identified quantitative trait loci (QTL), and we assessed QTL regions and candidate loci for ...

2011-05-18

409

Annual Report 1999. Electric power in Sweden  

Energy Technology Data Exchange (ETDEWEB)

Barsebaeck 1 was closed on 30 November 1999. Barsebaeck's output of approximately 4 TWh per year will primarily be replaced by imports from coal-fired plants in Denmark and Germany. During the year, the closure of Swedish fossil-fired condensing power stations continued. With that, over 3,000 MW of peak-load power has been shut down during recent years. Consequently, situations entailing shortages of power can arise. On the deregulated electricity market, it is only the system operators that have a satisfactory overview of the overall electricity balance. The Swedish Power Association has thus lobbied the government as regards the need to elucidate Svenska Kraftnaet's responsibility. In a governmental decision from December, Svenska Kraftnaet was given the task of, among other things, monitoring the available capacity during peak loads and developing market instruments that can contribute to safeguarding the availability of power during peak loads. Svenska Kraftnaet ...

2000-07-15

410

[Urinary infection in geriatric short stay: value of urinary strips].  

Science.gov (United States)

The blinded study of CBUE (cytobacteriological urine examination) test strips was carried out in 100 patients (65 women, 35 men), mean age 85.52 +/- 6.28 years, admitted for a short stay in a geriatrics department. Urinary infection was present in 19% of the cases. Typical clinical signs (pollakiuria, dysuria, hematuria, burning upon voiding) were rare, less than 10%. General signs, such as deterioration of general status (65% of the cases) and loss of autonomy (53% of the cases), on the other hand, were predominant and their relatively unspecific nature required a reliable screening test for urinary infection. Good results of sensitivity (89.5%), specificity (98.7%), and the leukocytes/nitrites values, confirmed the validity of the urine test strip in hospitalized elderly patients. In addition, the negative predictive value of the combination leukocytes and nitrites (90.8%) would have prevented 71 samples from being sent to the laboratory for ...

1997-01-01

411

Role of the Yersinia pestis Ail Protein in Preventing a Protective Polymorphonuclear Leukocyte Response During Bubonic Plague.  

Science.gov (United States)

The ability of Yersinia pestis to forestall the mammalian innate immune response is a fundamental aspect of plague pathogenesis. In this study, we examined the effect of Ail, a 17-kDa outer membrane protein that protects Y. pestis against complement-mediated lysis, on bubonic plague pathogenesis in mice and rats. The Y. pestis ail mutant was attenuated for virulence in both rodent models. The attenuation was greater in rats than in mice, which correlates with the ability of normal rat serum, but not mouse serum, to kill ail-negative Y. pestis in vitro. Intradermal infection with the ail mutant resulted in an atypical, subacute form of bubonic plague associated with extensive recruitment of polymorphonuclear leukocytes (PMN or neutrophils) to the site of infection in the draining lymph node and the formation of large purulent abscesses that contained the bacteria. Systemic spread and mortality were greatly attenuated, however, and a productive ...

2011-10-01

412

Regulation of macrophage accessory cell activity by mycobacteria. I. Ia expression in normal and irradiated mice infected with Mycobacterium mycroti  

International Nuclear Information System (INIS)

CBA/Ca mice were infected by either the intravenous or intraperitoneal route with Mycobacterium microti and the subsequent changes in local macrophage populations examined. Following infection, the number of macrophages increased and they showed greater expression of both MHC Class II molecules. This response was not dependent on viability of the mycobacteria, in contrast to reports with other microorganisms such as Listeria. Studies in sublethally irradiated mice indicated that persistent antigen could give rise to a response after a period of host recovery which was radiation dose dependent. This procedure also highlighted differences in the regulation of different murine class II antigens in vivo, as seen by delayed re-expression of I-E antigens. Macrophage accessory cell function, as assessed by an in vitro T cell proliferation assay, correlated with Ia expression after fixation, but not after indomethacin treatment; this highlights the ...

413

Predominant and common cause of urinary tract infection(s) in sukkur city  

International Nuclear Information System (INIS)

To examine and evaluate the predominant and common etiologic agent(s) of urinary tract infection (UTI) in Sukkur city and to determine their current antibiotic susceptibility/resistance trends. Nine hundred sixty six patients out of 1430 abnormal urine reports (showing significant abnormalities such as protein, pus, red cells) were asked to give second sample. The urine samples were examined by both urine test strip (Combur 10 Test, Roche) and microscopically (wet preparation) followed by culture and sensitivity. The culture sensitivity was done on urine samples of which bacterial numbers were estimated as more than 105CFU. The study was conducted at Safeway Diagnostic and Research Laboratory Sukkur and the Department of Microbiology, Shah Abdul Latif University Khairpur, Sindh from March 2001 to March 2003. Eight hundred fifty-two (88.2%) showed Escherichia spp followed by Klebsiella spp (6.9%) and proteus spp (4.9%). These showed 95%, 90%, 90% sensitivity to ...

2001-03-01

414

Ixodes ricinus: vector of a hitherto undescribed spotted fever group agent in Switzerland.  

Science.gov (United States)

A tick/rickettsial survey in various parts of Switzerland revealed the presence of a new, hitherto undescribed spotted fever group rickettsia ("Swiss agent") in up to 11.7% of I. ricinus collected off vegetation. Infection in ticks was found to be generalized with rickettsiae developing intracellularly and occasionally also intranuclearly. As a result of massive growth in ovarial tissues, including the germinative cells, the rate of transovarial and filial infection was 100%. The "Swiss agent" appears to be nonpathogenic for guinea pigs, domestic rabbits, and Swiss mice, but in male meadow voles (Microtus pennsylvanicus) it produces a microscopically detectable infection in the tunica vaginalis. The rickettsia grows well in tissue culture systems including chick embryo fibroblast, Vero, and vole tissue cells, when inoculated via yolk sac into 5-day-old hens' eggs, it kills 100% of the embryos after 5 to 7 days. Antigenic ...

1979-12-01

415

Characteristic findings of pediatric inpatients with pandemic (H1N1) 2009 virus infection among severe and nonsevere illnesses  

British Library Electronic Table of Contents (United Kingdom)

We analyzed the clinical features of inpatients at a Japanese pediatric department who were infected with pandemic (H1N1) 2009 virus. Study participants included 46 children hospitalized from July 2009 to January 2010. Infection with the virus was confirmed using real-time reverse transcriptase polymerase chain reaction (RT-PCR). The epidemic month was October 2009; 34 patients were boys, and median age was 7?years. Pandemic influenza-associated respiratory diseases included pneumonia (n?=?42), bronchitis (n?=?3), and pharyngitis (n?=?1). The median time from onset to admission was 3?days. Children were divided into those with severe (n?=?32) versus nonsevere illnesses (n?=?14) according to Japanese guidelines. Significant features in the severe group were younger age, previous asthmatic a...

2011-01-01

416

A versatile and potentially general approach to the targeting of specific cell types by retroviruses: Application to the infection of human cells by means of major histocompatibility complex class I and class II antigens by mouse ecotropic murine leukemia virus-derived viruses  

Energy Technology Data Exchange (ETDEWEB)

A technique for delivering genes carried by recombinant retroviruses into specific cell types could have numerous applications in oncology, developmental biology, and gene therapy. As a first step toward this remote goal the authors designed a procedure allowing in vitro cell targeting by retroviruses. Biotinylated antibodies against the viral envelope protein on one side, and against specific cell membrane markers on the other side, were bridged by streptavidin and used to link the virus to the host. The method was successfully used to infect human cells with ecotropic murine retroviruses by means of major histocompatibility complex class I and class II antigens and appears easily adaptable to other cell, membrane markers. Moreover, the sequential protocol they design, although allowing infection of human cells, requires less stringent safety constraints than would handling of amphotropic virus stocks.

1989-12-01

417

[Dysspermia due to inflammation. The evaluation of sperm cultures].  

Science.gov (United States)

The study evaluates 160 cases of positive spermioculture taken from 522 sterile individuals examined by the authors at the Couple Sterility Outpatient unit in Department A of the Institute of Gynecology and Obstetrics at Turin University during the period between January 1984 and December 1993. The germs responsible for infection were assayed in order to evaluate the strains which showed the highest incidence every year. Whereas there was no significant change in the absolute number of cases of sterility over the period, the number of cases caused by infection increased significantly during the second five-year period. It was found that the germs predominantly implicated in the genesis of male sterility formed part of the so-called mixed flora group, responsible in women for syndromes of often asymptomatic bacterial vaginosis which are not identified and consequently not treated. PMID:8559444

418

Use of flow cytometry to compare the antimicrobial efficacy of silver-containing wound dressings against planktonic Staphylococcus aureus and Pseudomonas aeruginosa  

British Library Electronic Table of Contents (United Kingdom)

Abstract Silver-impregnated wound dressings continue to be routinely used for the management of infected wounds, or wounds that are at risk of becoming infected. The ability of antimicrobials that have been incorporated into wound dressings to kill microorganisms within the dressing requires appropriate evaluation using in vitro models. In vitro models that have been exploited for this purpose have included the corrected zone of inhibition and the log reduction assay. However, these and other related culturable-based assays are purported to have poor correlation with the overall microbicidal barrier activity of an antimicrobial wound dressing. This is because culturable-based methods only retrospectively indicate bacterial cell death and do not take into account viable but nonculturable st...

2011-01-01

419

Toxicity and gross pathology of ivermectin bath treatment in sea bream Sparus aurata, L.  

British Library Electronic Table of Contents (United Kingdom)

The isopod parasite Ceratothoa oestroides becomes hard to eradicate in intensive fish rearing systems and in addition to causing weight loss in adult fish it causes mortalities in larval and juveniles stages of sea bass and sea bream. Faced with the fast emergence of this infection in Adriatic finfish facilities, an effective compound had to be tested for bath treatment. Ivermectin was chosen for this purpose on the basis of extensive practice in northern European countries which used ivermectin administered in food with good results in treatment of Lepeophtheirus sp. and Caligus sp. infections. For determination of toxicity of ivermectin, a short-term toxicity bioassay on 40-day-old sea bream, Sparus aurata, L., was conducted, following FAO and UNEP procedures for methodology in aquatic t...

2006-01-01

420

Quantitation of infectious myonecrosis virus in different tissues of naturally infected Pacific white shrimp, Litopenaeus vannamei, using real-time PCR with SYBR Green chemistry  

British Library Electronic Table of Contents (United Kingdom)

The Pacific white shrimp, Litopenaeus vannamei, is the most important shrimp species in volume in world aquaculture. However, in recent decades, outbreaks of diseases, especially viral diseases, have led to significant economic losses, threatening the sustainability of shrimp farming worldwide. In 2004, Brazilian shrimp farming was seriously affected by a new disease caused by the Infectious myonecrosis virus (IMNV). Thus, disease control based on rapid and sensitive pathogen detection methods has become a priority. In this study, a specific quantitation method for IMNV was developed using real-time PCR with SYBR Green chemistry and viral load of the principal target tissues of chronically infected animals was quantified. The quantitative analysis revealed that mean viral load ranged from ...

2011-01-01

421

Omental pedicle flap used to treat a bronchopleural fistula after diaphragma--pericardio-pleuropneumonectomy.  

Science.gov (United States)

In a 47-year-old male patient a bronchopleural fistula was apparent 22 days after extended right-sided diaphragma-pericardio-pleuro-pneumonectomy for pleuramesothelioma. The thoracic cavity was infected. Rethoracotomy was performed and the fistula was closed using an omental pedicle flap. The bronchial stump became tight and the cavity fluid became sterile. No abdominal complications were seen. The patient died 8 months later from malignant pericardial infiltration. The ability of greater omentum to revascularize ischemic tissue, to absorb fluid and to resist local infection is proved and used in several subspecialities of surgery. Nevertheless the use of the greater omentum in the management of bronchopleural fistula has been rarely published. The reported case shows that the closure of a large bronchopleural fistula is possible by using the attributes of the omental tissue. PMID:2264043

1990-10-01

422

Isolation and molecular identification of small ruminant mycoplasmas in Jordan  

British Library Electronic Table of Contents (United Kingdom)

Mycoplasma infections of small ruminants are known to exist in the Mediterranean region, Asia, Africa and cause significant economic impacts but little is known of the Mycoplasma spp. in sheep and goats in the Middle East. During the period of 2002-2003, 104 flocks of local sheep and goats (17 sheep, 27 goat and 60 mixed flocks) were surveyed for the occurrence of mycoplasma infections in Northern Jordan. The clinical signs seen in the studied flocks were, to varying degrees, mastitis in sheep and goats, arthritis, mainly in kids, and pneumonia in both sheep and goats of most age groups. Small ruminant farms were sampled and pooled milk samples and nasal swabs were collected for culture and isolation of mycoplasma. Mycoplasmas were isolated from 17 (26%) of the 62 milk samples and 12 (3.9%...

2006-01-01

423

Inhibitory effect of ?/?-carrageenan from red alga Tichocarpus crinitus on the development of a potato virus X infection in leaves of Datura stramonium L.  

British Library Electronic Table of Contents (United Kingdom)

The effect of ?/?-carrageenan from red alda Tichocarpus crinitus on the development of a potato virus X (PVX) infection in the leaves of Datura stramonium L. has been studied. The treatment of leaves with carrageenan stimulates a protein synthesis in the cells, causing an increase in the size of nucleoli and in the number of mitochondria and membranes of the rough endoplasmic reticulum. At the same time, such treatment slightly stimulates lytic processes, causing an increase in the number of smooth endoplasmic reticulum cisternae, dictyosomes, and cytoplasmic vacuoles and the formation of cytoplasmic electron-transparent zones. The carrageenan-induced stimulation of lytic processes results in the destruction of viral particles and can be considered as one of the defense mechanisms, prevent...

2010-01-01

424

Inhibition of prepenetration processes of the powdery mildew Golovinomyces orontii on host inflorescence stems is reduced in the Arabidopsis cuticular mutant cer3 but not in cer1  

British Library Electronic Table of Contents (United Kingdom)

The obligate biotrophic fungus Golovinomyces orontii causes powdery mildew (PM) disease on its host Arabidopsis thaliana. Most research on the G. orontii?Arabidopsis pathosystem uses rosette leaves as experimental materials, so little is known about the behavior of G. orontii on other Arabidopsis organs. We thus conducted microscopic analyses of the PM infection process on leaves, stems, fruits and roots of Arabidopsis. Adaxial and abaxial surfaces of mature rosette leaves supported G. orontii infection, but growth was somewhat suppressed on cauline leaves. Prepenetration processes (germination and appressorium formation) were strongly inhibited on stems, fruits and roots. To test the effect of alterations in the Arabidopsis cuticle on the inhibition of prepenetration processes on stems, w...

2011-01-01

425

Hepatitis B and C in dialysis units in Iran: Changing the epidemiology  

British Library Electronic Table of Contents (United Kingdom)

Abstract Hepatitis B (HBV) and C (HCV) viruses are the most important infections transmitted by the parenteral route in patients receiving maintenance dialysis. The prevalence varies markedly from country to country. The aim of this study is to review the efficacy of the strategies to reduce the incidence of these infections and the trend of results in Iran. As a routine, all hemodialysis patients in Iran have biannual blood samples for assessment of serum HBSAg, HBS Abs, and HCV Abs. The data are collected in the Ministry of Health. For statistical analysis, prevalence, and incidence were calculated. There is an increasing prevalence/incidence of end-stage renal disease (ESRD) in Iran, from 238/49.9 pmp in 2000 to 357/63.8 pmp in 2006. The prevalence of positive HBSAg and HCV Abs decrease...

2008-01-01

426

Hearing loss in Turner syndrome  

British Library Electronic Table of Contents (United Kingdom)

ObjectiveTo address the characteristics of hearing loss in patients with Turner syndrome (TS), we evaluated hearing levels of patients with TS and analyzed causative factors.Study designThirty-three patients with TS (8 to 40 years of age) were studied through the use of audiological measurements, and causative factors were explored.ResultsTwenty cases (35 of 66 ears tested) showed high-frequency (8 kHz) sensory neural hearing loss (HFQ-SNHL). Fifteen cases (26 ears) and 15 cases (24 ears) of the impaired 20 cases were unresponsive to distortion-product otoacoustic emissions and transient-evoked otoacoustic emissions, respectively. HFQ-SNHL showed little relation to the history of middle ear infection and puberty, although middle ear infections were seen in 11 of the 20 cases. The hearing t...

2006-01-01

427

Ergosterol analyses of oil palm seedlings and plants infected with Ganoderma  

British Library Electronic Table of Contents (United Kingdom)

Basal stem rot of oil palm (OP) by Ganoderma boninense is of major economic concern and it is the predominant disease of OP in SE Asia. Also, other plantation crops are affected by Ganoderma. The early detection of symptoms is crucial for control, although effective methods remain elusive. Ergosterol is the principal sterol of fungi and plays an essential role in the cell membrane and other cellular constituents. The analysis of ergosterol is useful for fungal detection in solid plant substrates. The present report compares ergosterol concentration in sound and decayed OP seedlings and mature plants using HPLC with diode array detection. The disease of OP requires to be considered as a white rot process where fungal biomass will increase from a low to high level as the infection progresses...

2011-01-01

428

Effect of an Ostertagia ostertagi infection on the transcriptional stability of housekeeping genes in the bovine abomasum  

British Library Electronic Table of Contents (United Kingdom)

Quantitative Real-Time PCR (qRT-PCR) is a widely used tool to study host responses against parasites. A crucial step in the gene quantification process is the normalization of the expression data against stable housekeeping genes (HKGs). However, in recent years, several reports have showed that the transcriptional levels of such HKGs can change dramatically, especially when cellular changes appear in the tissues investigated. The aim of the current study was to assess the variability of 11 putative HKGs in bovine abomasal tissue during an infection with the parasitic nematode Ostertagia ostertagi. Gene transcription levels of selected potential HKGs were measured by qRT-PCR and the expression stabilities evaluated using geNorm, NormFinder, and The Mann-Whitney-U test. The analysis showed ...

2011-01-01

429

Comparison of fluorescence in situ hybridisation using peptide nucleic acid probes, Gram stain/acridine orange leukocyte cytospin and differential time to positivity methods for detection of catheter related bloodstream infection in patients after haematopoietic stem cell transplantation  

British Library Electronic Table of Contents (United Kingdom)

Abstract In 46 febrile neutropenic patients who had undergone haematopoietic stem cell transplantation, the fluorescence in situ hybridisation using peptide nucleic acid probes (PNA FISH), Gram stain/acridine orange leukocyte cytospin (Gram/AOLC), and differential time to positivity (DTP) methods were performed for detection of catheter related bloodstream infections (CRBSIs). As compared with the DTP method (which detected 11 patients with CRBSI), the PNA FISH and the Gram/AOLC methods detected ten of 11 CRBSI patients, resulting in a sensitivity, specificity, negative predictive value and positive predictive value of 91%, 100%, 97% and 100%, respectively, for the PNA FISH method as well as for the Gram/AOLC method.

2010-01-01

430

Causes of morbidity among HIV-infected children on antiretroviral therapy in primary care facilities in Lusaka, Zambia  

British Library Electronic Table of Contents (United Kingdom)

Summary Objectives To describe the pattern of incident illness in children after initiation of antiretroviral therapy (ART) in a large public health sector programme in Lusaka, Zambia. Methods Systematic chart review to retrospectively extract data from medical records of children (i.e. <15 years) initiating ART in the Lusaka, Zambia public sector. Incident conditions were listed separately and then grouped according to broad categories. Predictors for incident diagnoses were determined using univariate and multivariable analysis. Results Between May 2004 and June 2006, 1705 HIV-infected children initiated ART. Of these, 1235 (72%) had their medical records reviewed. Median age at ART initiation was 77 months and 554 (45%) were females. Eight hundred and forty-one (68%) children had an inc...

2009-01-01

431

Cats and goat whey associated with Toxoplasma gondii infection in pigs.  

Science.gov (United States)

In organic livestock production systems, farm-management factors are thought to play an important role in the on-farm prevalence of Toxoplasma gondii. Serological results and the results of an HACCP analysis were combined to determine important risk factors for the prevalence of this protozoan parasite. Mathematical analysis demonstrated that feeding goat whey to pigs and the presence of a high number of cats were positively correlated to T. gondii seroprevalence in pigs. Not covering roughage and the farmers' assumption that pigs can come into contact with cat feces also showed a positive relationship. In order to decrease the risk of T. gondii infecting their pigs, farmers should limit the access and number of cats on their farms and refrain from feeding goat whey to their pigs. PMID:16989566

2006-01-01

432

Bortezomib induces apoptosis in T lymphoma cells and natural killer lymphoma cells independent of Epstein-Barr virus infection  

British Library Electronic Table of Contents (United Kingdom)

Abstract Epstein-Barr virus (EBV), which infects not only B cells, but also T cells and natural killer (NK) cells, is associated with multiple lymphoid malignancies. Recently, the proteasome inhibitor bortezomib was reported to induce apoptosis of EBV-transformed B cells. We evaluated the killing effect of this proteasome inhibitor on EBV-associated T lymphoma cells and NK lymphoma cells. First, we found that bortezomib treatment decreased the viability of multiple T and NK cell lines. No significant difference was observed between EBV-positive and EBV-negative cell lines. The decreased viability in response to bortezomib treatment was abrogated by a pan-caspase inhibitor. The induction of apoptosis was confirmed by flow cytometric assessment of annexin V staining. Additionally, cleavage o...

2011-01-01

433

Association between the number of blood cultures and appropriateness of care for suspected bacteremic urinary tract infection in the elderly  

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to evaluate the association between the number of blood cultures collected and the appropriateness of care for suspected bacteremic community-acquired urinary tract infection (UTI) in the elderly. We retrospectively evaluated the medical records of 129 patients with UTI >65?years old admitted to a large community-based training hospital in Japan from 1 January 2006 to 31 December 2009. We assessed the association between the number of blood cultures collected and the appropriateness of care received, as well as other factors. Two-thirds of the patients were women, and patients >85?years old accounted for 45.0% of the cases. Most of the organisms isolated from the urine and blood were Escherichia coli (65.4?67.0%). More than two blood cultures were collected ...

2011-01-01

434

Application of a leukocyte and nitrite urine test strip to the management of children with neurogenic bladder.  

Science.gov (United States)

A urine leukocyte count of > or = 50/mm3 together with a bacterial count of > or = 10(5) colony-forming units (CFUs) per milliliter was used to define significant infection in 160 children with neurogenic bladder and evaluate the leukocyte and nitrite components of the Chemstrip 9 test. A Chemstrip 9 leukocyte reading of or = 500 leukocytes together with a positive nitrite reaction occurred in 18 children and had a sensitivity of 40% with a 100% positive predictive value for infection. Other combinations of Chemstrip 9 leukocyte and nitrite reactions were unhelpful or of uncertain value. Selection of up to three specimens from each patient increased the number of samples to 360 and provided general confirmation of the above conclusions. Nitrofurantoin may reduce the sensitivity of the nitrite strip reaction. PMID:8359003

1993-07-01

435

Adoptive immunotherapy with virus-specific T cells  

British Library Electronic Table of Contents (United Kingdom)

Viral infections are still common causes of morbidity and mortality in immunosuppressed patients after allogeneic hematopoietic stem cell transplantation. Infections caused by virus such as cytomegalovirus, adenovirus and Epstein-Barr virus are well-known. In addition, several other viruses such as polyomavirus and human herpesvirus 6 have been recently reported to be causes of significant complications. As the delay in recovery of virus-specific cellular immune response after transplant is associated with viral reactivation and viral disease, adoptive immunotherapy to restore virus-specific cellular immunity is an attractive option. Recent clinical trials showed the safety and effectiveness of adoptive immunotherapy against viral diseases. In this review, we summarize the current status o...

2011-01-01

436

Wild-type p53 is not a negative regulator of simian virus 40 DNA replication in infected monkey cells.  

UK PubMed Central (United Kingdom)

To analyze the proposed growth-inhibitory function of wild-type p53, we compared simian virus 40 (SV40) DNA replication in primary rhesus monkey kidney (PRK) cells, which express wild-type p53, and...Full Text Available

1993-02-01

437

Understanding feline heartworm infection: disease, diagnosis, and treatment.  

Science.gov (United States)

Feline heartworm disease is a very different clinical entity from canine heartworm disease. In cats, the arrival and death of immature heartworms in the pulmonary arteries can cause coughing and dyspnea as early as 3 months postinfection. Adult heartworms suppress the function of pulmonary intravascular macrophages and thus reduce clinical disease in chronic feline heartworm infection. Approximately 80% of asymptomatic cats self-cure. Median survival time for symptomatic cats is 1.5 years, or 4 years if only cats living beyond the day of presentation are considered. Aberrant worm migration is more frequent than it is in dogs, and sudden death can occur with no prior clinical signs. The bacterial endosymbiont Wolbachia likely contributes to the inflammatory pathology of heartworm disease, but its role is not yet fully clear. Unfortunately, the diagnosis, treatment, and management of feline heartworm disease are far from simple. Antemortem diagnosis is hampered by ...

2010-11-01

438

Tissue tropism and neuroinvasion of West Nile virus do not differ for two mouse strains with different survival rates  

UK PubMed Central (United Kingdom)

West Nile virus (WNV) is a mosquito-borne flavivirus that infects the central nervous system of humans and other animals. In this study, we found that C3H/HeN (C3H) mice exhibited a higher morbidity...Full Text Available

2007-11-25

439

Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia  

UK PubMed Central (United Kingdom)

Chronic HTLV-I (human T cell lymphotropic virus type I) infection may cause adult T cell leukemia/lymphoma (ATL), a disease with dismal long-term prognosis. The HTLV-I transactivator, Tax, initiates...Full Text Available

2010-12-20

440

The Complete Genome Sequence of Yersinia pseudotuberculosis IP31758, the Causative Agent of Far East Scarlet-Like Fever  

UK PubMed Central (United Kingdom)

The first reported Far East scarlet-like fever (FESLF) epidemic swept the Pacific coastal region of Russia in the late 1950s. Symptoms of the severe infection included erythematous skin rash and desquamation,...Full Text Available

2007-08-01

441

Telavancin versus Standard Therapy for Treatment of Complicated Skin and Skin Structure Infections Caused by Gram-Positive Bacteria: FAST 2 Study  

UK PubMed Central (United Kingdom)

Telavancin is a bactericidal lipoglycopeptide with a multifunctional mechanism of action. We conducted a randomized, double blind, active-control phase II trial. Patients ≥18 years of age with...Full Text Available

2006-03-01

442

Susceptibility of the human retrovirus XMRV to antiretroviral inhibitors  

Science.gov (United States)

BackgroundXMRV (xenotropic murine leukemia virus-related virus) is the first known example of an exogenous gammaretrovirus that can infect humans. A limited number of reports suggest that XMRV is intrinsically resistant to many of the antiretroviral drugs used to treat HIV-1 infection, but is sensitive to a small subset of these inhibitors. In the present study, we used a novel marker transfer assay to directly compare the antiviral drug sensitivities of XMRV and HIV-1 under identical conditions in the same host cell type.ResultsWe extend the findings of previous studies by showing that, in addition to AZT and tenofovir, XMRV and HIV-1 are equally sensitive to AZddA (3'-azido-2',3'-dideoxyadenosine), AZddG (3'-azido-2',3'-dideoxyguanosine) and adefovir. These results indicate that specific 3'-azido or acyclic nucleoside analog inhibitors of HIV-1 reverse transcriptase (RT) also block XMRV infection with comparable efficacy ...

2010-08-31

443

Salmonella enterica Serovar Typhimurium Expressing a Chromosomally Integrated Copy of the Bacillus anthracis Protective Antigen Gene Protects Mice against an Anthrax Spore Challenge  

UK PubMed Central (United Kingdom)

Protective immunity against infection with Bacillus anthracis is almost entirely based on a response to the protective antigen (PA), the binding moiety for the two other toxin components....Full Text Available

2003-07-01

444

Safety and immunogenicity of ERA strain of rabies virus propagated in a BHK-21 cell line.  

UK PubMed Central (United Kingdom)

The ERA strain of rabies virus was propagated in a baby hamster kidney cell line (BHK-21/C13). The viral titer was 10(1.8) tissue culture infective doses (TCID) higher than that of commercial ERA vaccine....Full Text Available

1989-10-01

445

SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques  

UK PubMed Central (United Kingdom)

BackgroundHIV infection causes a qualitative and quantitative loss of CD4+ T cell immunity. The institution of anti-retroviral therapy (ART) restores CD4+ T...Full Text Available

446

Presence of the CYP2B6 516G> T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients  

UK PubMed Central (United Kingdom)

BackgroundThe 516G > T polymorphism in exon 4 of the CYP2B6 gene has been associated with increased plasma Efavirenz (EFV) concentrations. EFV concentrations...Full Text Available

447

Patterns of soil-transmitted helminth infection and impact of four-monthly albendazole treatments in preschool children from semi-urban communities in Nigeria: a double-blind placebo-controlled randomised trial  

UK PubMed Central (United Kingdom)

BackgroundChildren aged between one and five years are particularly vulnerable to disease caused by soil-transmitted helminths (STH). Periodic deworming has been shown to improve...Full Text Available

448

PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial  

UK PubMed Central (United Kingdom)

SummaryBackgroundInnovative prevention strategies for HIV-1 transmission are urgently needed. PRO2000 vaginal gel was efficacious against HIV-1 transmission in studies...Full Text Available

2010-10-16

449

Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice.  

UK PubMed Central (United Kingdom)

We have recently shown that viable Borrelia burgdorferi organisms induce a chronic infection associated with arthritis and carditis in severe combined immunodeficiency (scid) mice but not in immunocompetent...Full Text Available

1990-05-01

450

Monoclonal antibodies define genus-specific, species-specific, and cross-reactive epitopes of the chlamydial 60-kilodalton heat shock protein (hsp60): specific immunodetection and purification of chlamydial hsp60.  

UK PubMed Central (United Kingdom)

Ocular and urogenital tract infections with Chlamydia trachomatis can progress to chronic inflammatory diseases that produce blindness and tubal infertility. The pathophysiology of these chronic disease...Full Text Available

1992-06-01

451

Microbicides Development Programme: design of a phase III trial to measure the efficacy of the vaginal microbicide PRO 2000/5 for HIV prevention  

UK PubMed Central (United Kingdom)

BackgroundWith 2.5 million new HIV infections per year, effective preventive methods against HIV are urgently needed, especially in sub-Saharan Africa. MDP301 is an ongoing trial...Full Text Available

452

Mapping of TH1 helper T-cell epitopes on major secreted mycobacterial antigen 85A in mice infected with live Mycobacterium bovis BCG.  

UK PubMed Central (United Kingdom)

TH1 cytokine secretion was examined in response to synthetic peptides of the 85A component of the major secreted, fibronectin-binding antigen 85 complex from Mycobacterium tuberculosis in seven different...Full Text Available

1994-02-01

453

Maggot Therapy Takes Us Back to the Future of Wound Care: New and Improved Maggot Therapy for the 21st Century  

UK PubMed Central (United Kingdom)

In the 21st century, eighty years after William Baer presented his groundbreaking work treating bone and soft tissue infections with live maggots, thousands of therapists around the globe have rediscovered...Full Text Available

454

Local and systemic antibody response to bovine respiratory syncytial virus infection and reinfection in calves with and without maternal antibodies.  

UK PubMed Central (United Kingdom)

Enzyme-linked immunosorbent assays for the detection of immunoglobulin M (IgM), IgA, IgG1, and IgG2 antibodies against bovine respiratory syncytial virus (BRSV) were used to measure antibody responses...Full Text Available

1987-06-01

455

Intrahepatic cholangiocarcinoma presenting as liver abscess: report of two cases  

International Nuclear Information System (INIS)

Intrahepatic cholangiocarcinoma is the second most common primary malignant hepatic neoplasm. We describe two cases of intrahepatic cholangiocarcinoma which initially presented as liver abscess both clinically and radiologically. Mucin-hypersecretion from the tumor cells and extensive necrosis or secondary bacterial infection was responsible for the radiologic appearance of a liver abscess.=20

1998-10-01

456

Insecticide Treated Camouflage Sceening Reduces Sand Fly Numbers in Leishmania-Endemic Regions in Kenya  

Science.gov (United States)

Current U.S. military operations in deserts face persistent threats from sand flies that transmit human Leishmania. In this study we investigated the efficacy of artificial barriers treated with residual insecticide to potentially reduce the risk of human infection from leishmaniasis by reducing the...

457

Increased renal corticomedullary FDG activity in a patient of NHL-malignant or benign?  

International Nuclear Information System (INIS)

Authors describe diagnostic dilemma of differentiating pyelonephritis with lymphomatous involvement of kidney in a known case of lymphoma. FDG uptake pattern was non-discriminatory and pyelonephritis diagnosed retrospectively on follow up study. Authors emphasize the importance of recognition of features and subtle clues of infection evident on CT component of PET-CT. (author)

458

Hyperphosphorylation of the Rotavirus NSP5 Protein Is Independent of Serine 67 or NSP2, and the Intrinsic Insolubility of NSP5 Is Regulated by Cellular Phosphatases  

UK PubMed Central (United Kingdom)

The NSP5 protein is required for viroplasm formation during rotavirus infection and is hyperphosphorylated into 32- to 35-kDa isoforms. Earlier studies reported that NSP5 is not hyperphosphorylated...Full Text Available

2006-02-01

459

Histopathological and immunohistochemical findings of 20 autopsy cases with 2009 H1N1 virus infection.  

Science.gov (United States)

Twenty autopsy cases with 2009 pandemic influenza A (2009 H1N1) virus infection, performed between August 2009 and February 2010, were histopathologically analyzed. Hematoxylin-eosin staining, immunohistochemistry for type A influenza nucleoprotein antigen, and real-time reverse transcription-PCR assay for viral RNA were performed on formalin-fixed and paraffin-embedded specimens. In addition, the D222G amino acid substitution in influenza virus hemagglutinin, which binds to specific cell receptors, was analyzed in formalin-fixed and paraffin-embedded trachea and lung sections by direct sequencing of PCR-amplified products. There were several histopathological patterns in the lung according to the most remarkable findings in each case: acute diffuse alveolar damage (DAD) with a hyaline membrane (four cases), organized DAD (one case), acute massive intra-alveolar edema with variable degrees of hemorrhage (three cases), neutrophilic bronchopneumonia (five cases) and ...

2011-08-26

460

Genetic Characteristics, Coreceptor Usage Potential and Evolution of Nigerian HIV-1 Subtype G and CRF02_AG Isolates  

UK PubMed Central (United Kingdom)

HIV-1 CRF02_AG and subtype G (HIV-1G) account for most HIV infections in Nigeria, but their evolutionary trends have not been well documented. To better elucidate the dynamics of the epidemic in Nigeria...Full Text Available

461

Fungal Parasites of the Potato Cyst Nematode Globodera rostochiensis: Isolation and Reinfection.  

Science.gov (United States)

Fungal parasitism of eggs of the potato cyst nematode Globodera rostochiensis was Cladosporium cladosporoides did not infect eggs. No chitinase activity was found in these fungi, but protease activity was recorded in all. Growth of the fungi in cysts did not influence the number of physiologically disordered eggs. PMID:19287764

1990-10-01

462

Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers.  

UK PubMed Central (United Kingdom)

Although human T-cell lymphotropic virus type I (HTLV-I) is the etiologic agent of adult T-cell leukemia/lymphoma (ATL), the role of viral gene expression in the progression to and maintenance of the...Full Text Available

1992-04-01

463

Establishment of stable Huh-7 cell lines expressing various hepatitis C virus genotype 3a protein: an in-vitro testing system for novel anti-HCV drugs  

UK PubMed Central (United Kingdom)

BackgroundHepatitis C virus (HCV) infection is the leading cause of chronic hepatitis which progresses to hepatocellular carcinoma (HCC) afflicting > 170 million people worldwide....Full Text Available

464

Efficacy of the Carbocyclic 2?-Deoxyguanosine Nucleoside BMS-200475 in the Woodchuck Model of Hepatitis B Virus Infection  

UK PubMed Central (United Kingdom)

Daily oral treatment with the cyclopentyl 2′-deoxyguanosine nucleoside BMS-200475 at doses ranging from 0.02 to 0.5 mg/kg of body weight for 1 to 3 months effectively reduced the level of woodchuck...Full Text Available

1998-12-01

465

Duck Egg-Drop Syndrome Caused by BYD Virus, a New Tembusu-Related Flavivirus  

UK PubMed Central (United Kingdom)

Since April 2010, a severe outbreak of duck viral infection, with egg drop, feed uptake decline and ovary-oviduct disease, has spread around the major duck-producing regions in China. A new virus, named...Full Text Available

466

Differential Specificity and Immunogenicity of Adenovirus Type 5 Neutralizing Antibodies Elicited by Natural Infection or Immunization?  

UK PubMed Central (United Kingdom)

A recent clinical trial of a T-cell-based AIDS vaccine delivered with recombinant adenovirus type 5 (rAd5) vectors showed no efficacy in lowering viral load and was associated with increased risk of...Full Text Available

2010-01-01

467

Cutaneous manifestations in brucellosis.  

Science.gov (United States)

Brucellosis is a common worldwide zoonotic disease. Cutaneous manifestations are not specific and affect 1-14% of patients with brucellosis. Here, we describe 49-year-old female with fever and a diffuse maculopapular rash due to Brucella melitensis infection. Histopathology of skin biopsy revealed leukocytoclastic vasculitis; positive blood cultures for B. melitensis established the diagnosis of brucellosis. We provide a review of the relevant literature. PMID:21772606

2011-05-01

468

Comparison of prevalence, viral load, physical status and expression of human papillomavirus-16, -18 and -58 in esophageal and cervical cancer: a case-control study  

UK PubMed Central (United Kingdom)

BackgroundHuman papillomavirus (HPV) infection is a major risk factor for the development of nearly all cases of cervical cancer worldwide. The presence of HPV DNA in cases of esophageal...Full Text Available

469

Chimeric Matrix Proteins Encoded by Defective Proviruses with Large Internal Deletions in Human T-Cell Leukemia Virus Type 1-Infected Humans  

UK PubMed Central (United Kingdom)

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other diseases....Full Text Available

2000-05-01

470

Campylobacter jejuni, C. coli, and C. lari naturally present in Leghorn laying hens and the antibiotic resistance profiles of these organisms  

Science.gov (United States)

Campylobacter spp. are present in the intestinal tract and internal tissues of broiler breeder and broiler chickens. Campylobacter spp. are known to cause acute bacterial gastroenteritis in humans and raw poultry products have been implicated as a significant source of these infections. The object...

471

CD5 Is Dissociated from the B-Cell Receptor in B Cells from Bovine Leukemia Virus-Infected, Persistently Lymphocytotic Cattle: Consequences to B-Cell Receptor-Mediated Apoptosis  

UK PubMed Central (United Kingdom)

Bovine leukemia virus (BLV), a retrovirus related to human T-cell leukemia virus types 1 and 2, can induce persistent nonneoplastic expansion of the CD5+ B-cell population, termed...Full Text Available

2001-02-01

472

Analysis of the transcript encoding the latent Epstein-Barr virus nuclear antigen I: a potentially polycistronic message generated by long-range splicing of several exons.  

UK PubMed Central (United Kingdom)

The Epstein-Barr virus nuclear antigen (EBNA I) present in latently infected cells is encoded in a 2-kilobase exon contained in the BamHI K viral genomic fragment. This exon is, however, found within...Full Text Available

1985-12-01

473

Analysis of the mdr-1 Gene in Patients Co-Infected with Onchocerca volvulus and Loa loa Who Experienced a Post-Ivermectin Serious Adverse Event  

UK PubMed Central (United Kingdom)

Ivermectin (IVM) is exceptionally safe in humans, and is used for mass treatment of onchocerciasis and lymphatic filariasis. However, cases of encephalopathy, sometimes fatal, have been reported in...Full Text Available

2010-07-01

474

Adherence of Enterohemorrhagic Escherichia coli O157, O26, and O111 Strains to Bovine Intestinal Explants Ex Vivo?  

UK PubMed Central (United Kingdom)

We used bovine intestinal organ culture to study infection by enterohemorrhagic Escherichia coli serogroups O157, O26, and O111. We show colonization and attaching and effacing lesion...Full Text Available

2007-05-01

475

A single-stranded gap in human immunodeficiency virus unintegrated linear DNA defined by a central copy of the polypurine tract.  

UK PubMed Central (United Kingdom)

The structure of unintegrated human immunodeficiency virus type 1 (HIV-1) DNA from acutely infected human lymphoid cells was analyzed by nuclease S1 cleavage. We observed a unique, discrete single-stranded...Full Text Available

1991-05-01

476

Nature and distribution of mucosal lesions associated with enteropathogenic and enterohemorrhagic Escherichia coli in piglets and the role of plasmid-mediated factors.  

Science.gov (United States)

Bacterial attachment-effacement (att-eff) is emerging as an important virulence characteristic common to both enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC). The contribution of the plasmid-encoded EPEC adherence factor to the production of mucosal lesions and diarrhea was investigated in gnotobiotic piglets. Bacterial att-aff in the intestinal mucosa of piglets infected with plasmid-cured EPEC strain E2348/69 (O127) was indistinguishable from that in piglets infected with the parent strain, but the distribution of lesions was different; it occurred in the small intestines of 6 of 7 piglets infected with the parent strain compared with only 2 of 11 (P = 0.006) infected with the plasmid-cured strain. Plasmid-encoded factors in EPEC and EHEC strains did not appear to contribute to bacterial competition with normal gut microflora. Of 13 strains belonging to five EPEC ...

1989-04-01

477

Valuing future citizens' values regarding risk  

Energy Technology Data Exchange (ETDEWEB)

Valuing present citizen's values regarding the risks they face is an important aspect of risk assessment and risk acceptability. Conferences like VALDOR are held for this reason. Governments like Sweden have national referendums on various risk-prone enterprises. The results of these referendums can determine the future of these programs. In the United States, when guidelines are set for determining acceptable levels of risk, the relevant federal agencies are often required to provide a comment period regarding proposed guidelines in order to ascertain the judgments, including the weights place on certain values, of individual members of society as well as stakeholder groups. After the comment period ends, the agency decides on the acceptable level of risk, taking into account the comments from present citizens. Do we also have a duty to value the not-yet-existing values of future citizens, especially if the risks created by the activities of present ...

2006-09-15

478

Using the /phi/resund experimental data to evaluate the ARAC emergency response models  

Energy Technology Data Exchange (ETDEWEB)

A series of meteorological and tracer experiments, was conducted during May and June 1984 over the 20-km wide /O/resund strait between Denmark and Sweden for the purpose of studying atmospheric dispersion processes over cold water and warm land surfaces and providing the data needed to evaluate meso-scale models in a coastal environment. In concert with these objectives the data from these experiments have been used as part of a continuing effort to evaluate the capability of the three-dimensional MATHEW/ADPIC (M/A) atmospheric dispersion models to simulate pollutant transport and diffusion characteristics of the atmospheric during a wide variety of meteorological conditions. Since previous studies have focused primarily on M/A model evaluations over rolling and complex terrain at inland sites, the /O/resund experiments provide a unique opportunity to evaluate the models in a coastal environment. The M/A models are used by the Atmospheric Release Advisory ...

1988-07-01

479

The utilization of non-destructive method for in-service inspections in nuclear power components  

International Nuclear Information System (INIS)

To ensure safe and reliable power production nuclear power plants must be operated at high level. Non destructive in-service inspections are inseparable part of the effort. Non destructive in-service inspections are essential on the ground of degradation mechanisms existence in nuclear power components. Degradation processes are constituent of operation of each industrial installation including nuclear power plants. Mission of non-destructive testing is degradation detection, closer characterization of its parameters (dimensions) and to supply as much information as possible to nuclear power plant operator. Eddy current testing method can be assigned to surface - volumetric methods. Method enables inspection of electrically conductive materials. It is particularly suitable for inspection of non-ferromagnetic materials like austenitic stainless steel and brass. The method is used for detection of stress corrosion cracking, pitting corrosion or surface corrosion. The method experienced ...

2006-01-01

480

Sump Pool Flow Simulation during Fill-up Phase of LOCA Using on CFD for OPR1000 Plant  

Energy Technology Data Exchange (ETDEWEB)

During LOCA (Loss of Coolant Accident) in design bases accident (DBA), emergency core coolant supplements form a recirculation sump and cooled core and containment. When the double ended guillotine Break (DEGB) at the hot leg near steam generator, due to the jet impingement discharge flow, the debris could be potentially generated at pipe or wall nearby steam generator and be transported to the recirculation sump. Therefore, the debris, such as insulations and paint chips, could be accumulated and be clogged in the recirculation sump screen. If debris is blocked the sump strainer, the pressure drop is increased at the screen so as to increase the pressure loss of ECCS (Emergency Core Cooling System) pump NPSH (Net positive suction head). It is potentially influenced to decrease the long-term cooling capability of the recirculation sump. The recirculation sump screen clogging accident has happened in BWR of USA and Sweden. Considering the important to safety, US NRC ...

2009-10-15

481

SR 97 - Alternative models project. Discrete fracture network modelling for performance assessment of Aberg  

Energy Technology Data Exchange (ETDEWEB)

As part of studies into the siting of a deep repository for nuclear waste, Swedish Nuclear Fuel and Waste Management Company (SKB) has commissioned the Alternative Models Project (AMP). The AMP is a comparison of three alternative modeling approaches for geosphere performance assessment for a single hypothetical site. The hypothetical site, arbitrarily named Aberg is based on parameters from the Aespoe Hard Rock Laboratory in southern Sweden. The Aberg model domain, boundary conditions and canister locations are defined as a common reference case to facilitate comparisons between approaches. This report presents the results of a discrete fracture pathways analysis of the Aberg site, within the context of the SR 97 performance assessment exercise. The Aberg discrete fracture network (DFN) site model is based on consensus Aberg parameters related to the Aespoe HRL site. Discrete fracture pathways are identified from canister locations in a prototype repository design ...

1999-08-01

482

Review of wood fuel from early thinning and plantation cleaning in the Netherlands  

International Nuclear Information System (INIS)

Discussions regarding the use of wood fuels for commercial energy production in the Netherlands began in the 1990's. The main reasons for using wood fuel are: the political demand for using renewable energy, the need to reduce CO_2 emissions, and the lack of markets for surplus timber. Only 10 % of the area of Holland is forested. Therefore, early thinning and cleaning are important management tools for improving growth and producing better quality timber. The energy potential from early thinning and plantation cleaning could be between 400 000 and 570 000 dry tons annually. The Netherlands has not experience in harvesting energy wood. However, through the International Energy Agency/Bioenergy Agreement, knowledge gained in other countries, especially Denmark, Sweden and Finland, is being transferred to Holland. In 1996, there have been made field tests with Danish equipment. Although there are few technical barriers to wood fuel in the Netherlands, the economics ...

483

Radiosurgery for metastatic brain tumors  

International Nuclear Information System (INIS)

Stereotactic radiosurgery (SRS) precisely delivers high-dose radiation to a small target (usually less than 3-4 cm in diameter), in a single session with steep dose-fall, employing various radiation methods. SRS provides good tumor control for small brain metastases from various primary cancers, with minimal untoward effects on surrounding normal brain. This excellent tumor control prevents neurological death and maintains good activity of daily life. Although surgery with whole-brain radiation therapy (WBRT) remains an important option for patients with a solitary brain metastasis, SRS with or without WBRT should be considered in patients with a limited number of small tumors and a good prognosis. Many reports, as well as both retrospective and prospective reviews, have shown WBRT before or after SRS to improve local control and reduce new distant lesion emergence. However, upfront WBRT does not improve survival. There are two major delivery techniques, Gamma Knife (GK; Elekta AB, ...

2009-08-01

484

Preliminary studies of tunnel interface response modeling using test data from underground storage facilities.  

Energy Technology Data Exchange (ETDEWEB)

In attempting to detect and map out underground facilities, whether they be large-scale hardened deeply-buried targets (HDBT's) or small-scale tunnels for clandestine border or perimeter crossing, seismic imaging using reflections from the tunnel interface has been seen as one of the better ways to both detect and delineate tunnels from the surface. The large seismic impedance contrast at the tunnel/rock boundary should provide a strong, distinguishable seismic response, but in practice, such strong indicators are often lacking. One explanation for the lack of a good seismic reflection at such a strong contrast boundary is that the damage caused by the tunneling itself creates a zone of altered seismic properties that significantly changes the nature of this boundary. This report examines existing geomechanical data that define the extent of an excavation damage zone around underground tunnels, and the potential impact on rock properties such as P-wave and S-wave velocities. ...

2010-11-01

485

Microclimatic models. Estimation of components of the energy balance over land surfaces  

Energy Technology Data Exchange (ETDEWEB)

Climates at regional scale are strongly dependent on the interaction between atmosphere and its lower boundary, the oceans and the land surface mosaic. Land surfaces influence climate through their albedo, and the aerodynamic roughness, the processes of the biosphere and many soil hydrological properties; all these factors vary considerably geographically. Land surfaces receive a certain portion of the solar irradiance depending on the cloudiness, atmospheric transparency and surface albedo. Short-wave solar irradiance is the source of the heat energy exchange at the earth`s surface and also regulates many biological processes, e.g. photosynthesis. Methods for estimating solar irradiance, atmospheric transparency and surface albedo were reviewed during the course of this project. The solar energy at earth`s surface is consumed for heating the soil and the lower atmosphere. Where moisture is available, evaporation is one of the key components of the surface energy balance, because the ...

1996-12-31

486

Influence of fuel additives on performance of direct-injection diesel engine and exhaust emissions when operating on shale oil  

Energy Technology Data Exchange (ETDEWEB)

The article presents the comparative bench testing results of a naturally aspirated four stroke, four cylinder, water cooled, direct injection Diesel engine when running on shale oil that has been treated with multi-functional fuel additives. The purpose of the research is to evaluate the effectiveness of the fuel additives Marisol FT (Sweden) and SO-2E (Estonia) as well as to verify their ability to increase energy conversion and reduce brake specific fuel consumption, contamination and smoke opacity of the exhausts when fuelling the Diesel engine with shale oil. Test results show that application of these additives could be a very efficient means to improve diesel engine performance on shale oil, especially when operating at the light load range. The brake specific fuel consumption at light loads and speeds of 1400-2000 min{sup -1} reduces by 18.3-11.0% due to the application of the Marisol FT. The additive SO-2E proves to produce nearly the same effect. The ...

2005-07-01

487

IEA HPP Annex 29 - ground-source heat pumps overcoming technical and market barriers. Status report Norway  

International Nuclear Information System (INIS)

Norway is a member of Annex 29, 'Ground-Source Heat Pump Systems Overcoming Technical and Market Barriers' (2004-2006), organized under the umbrella of the International Energy Agency (IEA) and the IEA Heat Pump Programme (HPP). The 7 participating countries are Austria (Operating Agent), Canada, Japan, Norway, Spain, Sweden and the USA. The Norwegian participation is financed by ENOVA SF, and SINTEF Energy Research is responsible for planning and carrying out the Norwegian activities. This report provides a status for ground-source heat pump (GSHP) systems in Norway with regard to state-of-the-art technology, installation examples, geological data, costs and market opportunities. A Norwegian Internet home page for ground-source heat pump systems (www.energy.sintef.no/prosjekt/Annex29) is also presented. GSHP systems in Norway are classified as direct systems (groundwater and soil/ground) and indirect closed-loop systems (vertical-rock and horizontal-soil/ground). ...

488

Green nanotechnology in Nordic Construction: Eco-innovation strategies and Dynamics in Nordic Window Value Chains  

DEFF Research Database (Denmark)

This project analyzes Nordic trends in the development and industrial uptake of green nanotechno-logy in construction. The project applies an evolutionary economic perspective in analyzing the innovation dynamics and firm strategies in the window value chains in three Nordic countries, Denmark, Finland and Sweden. Hence the project investigates two pervasive parallel market trends: The emergence of the green market and the emergence of nanotechnology. The analysis investigates how a traditional economic sector such as the construction sector reacts to such major trends. Conclusions are multiple, but among the most important are: Eco-innovation has become the perhaps most important driver for innovation in the construction sector. Search into eco-innovative business opportunities is intense among all companies along the three analyzed Nordic window chains. While we generally find a low uptake of nanotechnology in the construction sector in the Nordic countries we do ...

2010-01-01

489

Grain boundary corrosion of copper canister material  

Energy Technology Data Exchange (ETDEWEB)

The proposed design for a final repository for spent fuel and other long-lived residues in Sweden is based on the multi-barrier principle. The waste will be encapsulated in sealed cylindrical canisters, which will then be placed in granite bedrock and surrounded by compacted bentonite clay. The canister design is based on a thick cast inner container fitted inside a corrosion-resistant copper canister. During fabrication of the outer copper canisters there will be some unavoidable grain growth in the welded areas. As grains grow they will tend to concentrate impurities within the copper at the new grain boundaries. The work described in this report was undertaken to determine whether there is any possibility of enhanced corrosion at grain boundaries within the copper canister. The potential for grain boundary corrosion was investigated by exposing copper specimens, which had undergone different heat treatments and hence had different grain sizes, to aerated ...

2001-03-01

490

Energy in Asia. An Outline of Some Strategic Energy Issues in Asia  

Energy Technology Data Exchange (ETDEWEB)

The Asian countries are expected to generate 45% of the world energy consumption and Japan is the absolutely greatest consumer in Asia, but China is the country that will be most important as a new consumer on the world energy markets. China, like India and later possibly even Japan try to change to natural gas as a source of energy as much as possible. This is causing a competition about the resources that can be reached by pipelines for gas, which in practice means those in Russia and Central Asia. Russia is trying to control the gas in Central Asia. The competition is also increasing about oil. China is becoming heavily dependent on Muslim countries in the Middle East and Central Asia. This also leads to an effort to increase the safety along the sea lanes, which may collide with the interests of other countries. Territorial conflicts with gas and oil as underlying elements exist in Asia. USA is a player on the energy market, who is using military means as well, but it is possible ...

2003-01-01

491

Dosimetry audit on the accuracy of 192Ir brachytherapy source strength determinations in Sweden  

Energy Technology Data Exchange (ETDEWEB)

The absorbed dose delivered to the patient in brachytherapy is directly proportional to the source strength in terms of the reference air-kerma rate (RAKR). Verification of this quantity by the hospitals is widely recognized as an important part of a quality assurance program. An external audit was performed on behalf of the Secondary Standard Dosimetry Laboratory at the Swedish Radiation Protection Authority (SSI). The aim was to investigate how accurately the source-strength in 192Ir brachytherapy is determined at Swedish hospitals. The SSI reference well-type ion chamber and calibrated equipment were used to measure the RAKR of an 192Ir source in each of the 14 Swedish afterloading units. Comparisons with values determined by vendors and hospitals were made. Agreement in values of RAKR as determined by SSI, hospitals and vendors were in all cases within the +-3% uncertainty (at a coverage factor of k=2), typically guaranteed by the vendors. The good agreement reflects the robustness ...

2007-11-15

492

Contamination profiles of short-chain polychlorinated n-alkanes in foodstuff samples from Japan  

Energy Technology Data Exchange (ETDEWEB)

Polychlorinated n-alkanes (PCAs) are group of chemicals manufactured by chlorination of liquid n-paraffin or paraffin wax that contain 30 to 70% chlorine by weight. Large amounts of PCAs are widely used as plasticizers for vinyl chloride, lubricants, paints, and flame retardants and number of other industrial applications. Annual global production of PCAs is approximately 300 kilo tones, with a majority having medium-carbon-chain (C14-C19) length. According to the investigation made by Kagaku Kogyo Nippon-Sha, the annual consumption of PCAs in Japan was about 83,000 tons in between 1986-2001. Short-carbon-chain (C10-C13) has been placed on the Priority Substance List under Canadian Environmental Protection Act and on the Environmental Protection Agency Toxic Release Inventory in the USA due to its potential to act as tumor promoters in mammals. Data on environment levels of PCAs is meager, nevertheless, PCAs have been measured at relatively high concentrations in biota from ...

2004-09-15

493

Combined distiller waste utilisation and combustion gases desulphurisation method. The case study of soda-ash industry  

Energy Technology Data Exchange (ETDEWEB)

In this paper, a concept of technology that can be helpful for lowering the negative influence of the synthetic (based on the Solvay process) soda ash plant on the natural environment is presented. We describe the desulphurisation of combustion gases from the factory's power plant, which is based on their absorption in the overflow of distiller waste. The excess of lime milk, which is added in the process of ammonia regeneration from filter liquor, results in a strong alkalinity of distiller waste. The high pH of distiller waste favours absorption of acidic combustion gases. The laboratory-scale tests showed about 80% efficiency of the desulphurisation process. The suspension samples we obtained consist mainly of CaCO{sub 3}. We suggest using the obtained solid phase as an adsorbent-insert in Fluidised Bed Combustion technology (FBC). Based on raw material prices, production costs, and average sell prices of the product, economic analysis of innovation was executed. Profits ...

2007-09-15

494

Boiling water reactors, pressurized water reactors, supercritical water reactors; Reacteurs a eau bouillante, a eau pressurisee, ou a eau supercritique  

Energy Technology Data Exchange (ETDEWEB)

This article gives an account of the recent development of light water reactors new concepts in the world. Different projects are being studied. The CE80+ from Combustion Engineering (CE) is a 1350 MWe-PWR-type reactor whose primary circuit is confined in a spherical metallic containment. This reactor was certified by NRC (national regulatory commission) in mid-1996. The APWR (advanced pressurized water reactor) is developed by MHI (Mitsubishi heavy industries) in a collaboration with Westinghouse, this PWR-type reactor fitted with 4 loops derived from the SP90 model that was developed by Westinghouse during the eighties. 2 units of ABWR (advanced boiling water reactor) were commissioned in Japan in 1996 and 1997, ABWR was certified by NRC in mid-1996. The BWR90+ is developed by ABB-atom (Sweden) and it represents a cautious advanced version of the BWR75. Passive reactors are reactors that rely only on potential energy (compressed gas, gravitational flow or ...

2001-07-01

495

A model for the calculation of vent clearing transients in pressure suppression systems  

International Nuclear Information System (INIS)

For the layout of a pressure suppression system of a light water cooled reactor (boiling water reactor) it is important to know the time dependent behavior of the vent clearing transient after a loss-of-coolant accident for two main reasons: time of the end of the vent clearing transient influences strongly the pressure and temperature maxima in the drywell and wetwell. Time-dependent behavior of the vent clearing transient influences pressure loads in the condensation pool of the wetwell and therefore pressure induced stresses to the structure. The time-dependent behavior of the water masses in the vent pipes and wetwell are described by the basic equations for a nonstationary incompressible friction flow: momentum equation, continuity equation and a correlation for the variation of the state of the gas volume in the wetwell above the water level. After many algebraic operations and integrations along the flow path, a single ordinary nonlinear differential equation for the variations ...

1975-09-01

496

Replication-defective vectors of reticuloendotheliosis virus transduce exogenous genes into somatic stem cells of the unincubated chicken embryo  

Energy Technology Data Exchange (ETDEWEB)

Replication-defective vectors derived from reticuloendotheliosis virus were used to transduce exogenous genes into early somatic stem cells of the chicken embryo. One of these vectors transduced and expressed the chicken growth hormone coding sequence. The helper cell line, C3, was used to generate stocks of vector containing about 10/sup 4/ transducing units per ml. Injection of 5- to 20-..mu..l volumes of vector directly beneath the blastoderm of unincubated chicken embryos led to infection of somatic stem cells. Infected embryos and adults contained unrearranged integrated proviral DNAs. Embryos expressed the transduced chicken growth hormone gene and contained high levels of serum growth hormone. Blood, brain, muscle, testis, and semen contained from individuals injected as embryos contained vector DNA. Replication-defective vectors of the reticuloendotheliosis virus transduced exogenous genes into chicken embryonic stem cells in vivo.

1989-06-01

497

Percutaneous drainage of abdominal abcess  

Energy Technology Data Exchange (ETDEWEB)

The mortality in undrained abdominal abscesses is high with a mortality rate ranging between 45 and 100%. The outcome in abdominal abscesses, however, has improved due to advances in image guided percutaneous interventional techniques. The main indications for the catheter drainage include treatment or palliation of sepsis associated with an infected fluid collection, and alleviation of the symptoms that may be caused by fluid collections by virtue of their size, like pancreatic pseudocele or lymphocele. The single liver abscesses may be drained with ultrasound guidance only, whereas the multiple abscesses usually require computed tomography (CT) guidance and placement of multiple catheters. The pancreatic abscesses are generally drained routinely and urgently. Non-infected pancreatic pseudocysts may be simply observed unless they are symptomatic or cause problems such as pain or obstruction of the biliary or the gastrointestinal tract. ...

2002-09-01

498

Magnetic resonance imaging: early detection of central nervous system involvement in acquired immunodeficiency syndrome (AIDS)  

International Nuclear Information System (INIS)

Central Nervous System (CNS) involvement, whether primary by the Human Immunodeficiency Virus - HIV - itself, or secondary (toxoplasmosis or lymphoma) is remarkably frequent in AIDS, in 40 to 70% of cases, depending upon the author. In order to study the natural history of this illness, a cohort of 25 asymptomatic seropositive patients have been established. Every 6 months these patients undergo biological and clinical examinations, as well as Magnetic Resonance brain scans. After two examinations at a 6 month's interval, the first results are reported. Out of these 25 cases, 9 present anomalies: One patient with diffuse cerebral atrophy and 8 others with high signal intensity areas on T2 weighted sequences, like those of the Multiple Sclerosis. No relationship could be demonstrated between the existence of these lesions and various criteria such as age, sex, risk factors and T4 cells count. The nature of these lesions is not lear. They certainly indicate early involvement of the CNS ...

499

Assessment of vesical-ureteral reflux in transplant patients using radionuclide cystography; Exploration scintigraphique des reflux vesico-renaux chez les patients transplantes renaux  

Energy Technology Data Exchange (ETDEWEB)

Direct radionuclide cystography is known to be sensitive and safe in children with suspected vesical-ureteral reflux. In this study we have investigated the utility of direct radionuclide cystography in renal transplant recipients with a recent history of pyelonephritis or recurrent urinary infections. Direct radionuclide cystography is a simple test, however it requires a rigorous methodology in order to obtain images during fill-in as well as during voiding in both men and women. The images must be interpreted using a rigorous image display methodology. Twenty-eight radionuclide cystographies were performed in 17 patients. Among the 17 tests performed for the initial diagnosis of reflux , 12 were positive. Four patients with positive results and four patients with negative results were also investigated by radiologic cystography. Similar results were obtained in those patients. Nine scintigraphies were done after treatment by surgery or teflon injection ; six of ...

1995-12-31

500

Argentinian doctors accused of spreading AIDS.  

Science.gov (United States)

The provincial ministry of health has taken over a dialysis center in La Plata, Argentina, following the discovery that at least 20 of the clinic's 34 regular patients have been infected with the human immunodeficiency virus (HIV). Catheters of the clinic's dialysis machines were found to be contaminated with HIV. The 5 physicians associated with the Centro Modelo de Dialisis have been discharged for negligence. 20 of the regular patients also contracted hepatitis C. Argentinian law stipulates that filters for the same patient must be changed after 4 times and prohibits the use of the same vessel to administer medication to more than 1 patient. Testimony from nurses at the La Plata clinic revealed that filters were reused for several patients and basic sanitary procedures were not followed. In 1990, 33 kidney disease patients at a dialysis center in Cordoba became infected with HIV and it was discovered that filters had been used up to 8 ...

1993-09-01