UK PubMed Central (United Kingdom)

A patient with Cushing's syndrome due to a nonresectable chromophobe adenoma underwent external irradiation of the hypothalamic-pituitary area. The signs of Cushing's syndrome ameliorated subsequently...Full Text Available

Science.gov (United States)

What genes are related to AEC syndrome? AEC syndrome is caused by mutations in the TP63 gene. This gene provides instructions for making a protein known as p63, which plays an...

Science.gov (United States)

Gun barrel vibrations lead to dispersion in the shot patterns. Thus, reducing these vibrations should lead to increased accuracy. Since the muzzle is the anti-node for all vibration modes and its vibrations have the greatest effect on shot dispersion, it ...

KoreaScience (Korea)

Full Text Available

Science.gov (United States)

No abstract available.

Science.gov (United States)

An almost linear optimization problem of importance in vibration isolation has been identified and algorithms were developed to minimize the forced vibrational response of structural systems. The constraints can be either displacements of accelerations. T...

UK PubMed Central (United Kingdom)

AIMS/BACKGROUND: This study was undertaken to document visual function and acuity in patients with Aicardi syndrome, and to determine whether there is any relation between ocular features of the syndrome...Full Text Available

UK PubMed Central (United Kingdom)

A previously unrecognized form of nystagmus associated with esotropia was described in the German literature by Adelstein and Cüppers in 1966 as the nystagmus blockage syndrome. Even though...Full Text Available

UK PubMed Central (United Kingdom)

Background/AimTo assess pathophysiology in irritable bowel syndrome (IBS).Methods122 IBS patients...Full Text Available

UK PubMed Central (United Kingdom)

The cause of the female urethral syndrome has previously been obscure, as it has been associated by definition with a lack of objective findings but a plethora of subjective complaints of retropubic...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Forced vibration experiment has been conducted for the reactor building of Sendai Unit 1 nuclear power plant. The beam vibrational behaviors of the outer shielding building and the internal concrete structure have been observed by using a 50 tf vibration for low frequency region, and a 10 tf vibration for high frequency region, respectively. The outline of the experimental methods, the data handling system and the major results of experiment are described. The experimental results were simulated by an analytical model. The proper vibrational frequency and the vibration modes obtained by the analysis were compared with those obtained by the experiment. By these comparisons, the adequacy of the analytical method employed for the design was confirmed.

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

Science.gov (United States)

In order to maintain a safe operation and availability of generating facilities, qualitative and quantitative assessment of piping vibration was performed vibration sources and damages of piping support was identified on the second piping system of Wolsun...

Science.gov (United States)

A standardized method of shock and vibration isolation for satellite tape recorders has been developed. Using readily avail- able components, the isolators ...

Energy Technology Data Exchange (ETDEWEB)

The objective of this study is to establish a construction plan for vibration analysis system of HANARO's rotating machinery. To achieve this purpose, as a first step, the references related to the vibration analysis system for the rotating machinery were investigated. In addition, to verify the possibility of condition monitoring of the pumps, vibration signals obtained from the vibration monitoring system were analyzed. The results show that using the accelerometers mounted on the bearing locations of the pumps can monitor the current status of the pump such as unbalance, misalignment, and bearing condition. Based on the results of this study, the construction plans for the vibration analysis system of HANARO have been established. The hardware of the vibration analysis system will be installed by the end of this year. It is expected that the ...

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Science.gov (United States)

... ULTRASONIC VIBRATION TO PORTLAND CEMENT-WATER PASTE REDUCES THE ULTIMATE COMPRESSIVE STRENGTH OF MORTARS ...

Science.gov (United States)

Not Available

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

International Nuclear Information System (INIS)

Forced vibration experiment has been conducted for the reactor building of Sendai Unit 1 nuclear power plant. The beam vibrational behaviors of the outer shielding building and the internal concrete structure have been observed by using a 50 tf vibration for low frequency region, and a 10 tf vibration for high frequency region, respectively. The outline of the experimental methods, the data handling system and the major results of experiment are described. The experimental results were simulated by an analytical model. The proper vibrational frequency and the vibration modes obtained by the analysis were compared with those obtained by the experiment. By these comparison, the adequacy of the analytical method employed for the design was confirmed. (Aoki, K.).

UK PubMed Central (United Kingdom)

Werner syndrome (WS) is characterized by premature onset of age-associated disorders and predisposition to cancer. The WS protein, WRN, encodes 3′ → 5′ DNA helicase and 3′...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe pathogenesis of visceral hypersensitivity, a characteristic pathophysiological feature of irritable bowel syndrome (IBS), remains elusive. Recent studies suggest a...Full Text Available

UK PubMed Central (United Kingdom)

Syndrome X is a combination or co-occurrence of several known cardiovascular risk factors (including central obesity, dyslipidemias, fatty liver disease, hyperinsulinemia, insulin resistance,...Full Text Available

UK PubMed Central (United Kingdom)

Patients with Alport syndrome progressively lose renal function as a result of defective type IV collagen in their glomerular basement membrane. In mice lacking the α3 chain of type IV collagen...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundIrritable bowel syndrome (IBS) and functional dyspepsia (FD) show considerable overlap and are both associated with psychiatric comorbidity. The present study aimed to...Full Text Available

UK PubMed Central (United Kingdom)

SummaryBackgroundQuality of life among women with irritable bowel syndrome may be affected by pelvic floor disorders.AimFull Text Available

UK PubMed Central (United Kingdom)

PurposeTo report unusual ocular manifestations of branchio-oculo-facial syndrome (BOFS) caused by a novel mutation in activating enhancer binding protein 2 alpha (TFAP2A).MethodsFull...Full Text Available

UK PubMed Central (United Kingdom)

AbstractA newly recognized syndrome, characterized by sudden death of farmed deer that are in good to excellent nutritional condition, with lesions of small intestinal mucosal hemorrhage...Full Text Available

UK PubMed Central (United Kingdom)

We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction...Full Text Available

UK PubMed Central (United Kingdom)

Werner Syndrome (WS) is an inherited disease characterized by premature onset of aging, increased cancer incidence, and genomic instability. The WS gene encodes a 1,432-amino acid polypeptide (WRN)...Full Text Available

UK PubMed Central (United Kingdom)

Thirteen fetuses (five twin, one triplet) were compromised by fetofetal transfusion syndrome in six pregnancies, five in the mid trimester, and one in the third trimester. This diagnosis, which was...Full Text Available

UK PubMed Central (United Kingdom)

At least implicitly, most clinical decisions represent an integration of disease and treatment-based risk assessments. Often, as is the case with acute coronary syndrome (ACS), these decisions need...Full Text Available

UK PubMed Central (United Kingdom)

Neurofibromatosis type 1 (NF-1) and tuberous sclerosis complex (TSC) are two familial syndromes known as phakomatoses that may be associated with endocrine tumors. These hereditary cutaneous...Full Text Available

UK PubMed Central (United Kingdom)

Objectives. We investigated increases in diarrheal illness detected through syndromic surveillance after a power outage in New York City on August 14, 2003.Methods....Full Text Available

UK PubMed Central (United Kingdom)

Antiplatelet agents are the cornerstone of treatment for patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). Clopidogrel, when added to aspirin, has demonstrated...Full Text Available

UK PubMed Central (United Kingdom)

Background & AimsData are conflicting on the benefit of selective serotonin reuptake inhibitors (SSRIs) for patients with irritable bowel syndrome (IBS);...Full Text Available

UK PubMed Central (United Kingdom)

This study was designed to identify the causes of the development of carpal tunnel syndrome (CTS) associated with end stage kidney disease (ESKD). A total of 112 patients with ESKD, 64 on hemodialysis...Full Text Available

Science.gov (United States)

... Attention Deficit Hyperactivity Disorder. In: Kurlan, R. (ed.) The Handbook of Tourette's Syndrome and Related Tic and Behavioral Disorders. ...

International Nuclear Information System (INIS)

Portuguese (Mar 1983). Brazil Furlanetto, RP Abucham Filho, J. Albertotti,

Science.gov (United States)

PMID:16912339

British Library Electronic Table of Contents (United Kingdom)

Background: Recent series describing the clinical presentation, response to therapy, and long-term outcome of Zollinger-Ellison syndrome are limited. Aims: To assess the clinical characteristics and long-term outcome of patients with Zollinger-Ellison syndrome. Methods: Over a 20-year period, patients with Zollinger-Ellison syndrome were enrolled in a prospective trial evaluating the efficacy of lansoprazole. Following dose stabilization, patients were followed on a 6-monthly basis with interval history, physical examination, endoscopy with gastric biopsies, gastric acid analysis and laboratory studies. Results: 72 patients (mean age 54+/-12 years, % male 58%, % Caucasian 69%) were prospectively enrolled. The clinical presentation was stereotypical for Zollinger-Ellison syndrome. Symptoms ...

Science.gov (United States)

This report is the final report on the seismic testing of reactor components conducted since 1977 with opening of the vibration laboratory at KAERI. In 1979, forced vibration testing of Wolsung-1 steam generator model using sine dwell and white nosie rand...

Science.gov (United States)

... The relatively large, low frequency multi-axis motions observed at the chest may be a contributor to discomfort in locomotive engineers. ...

International Nuclear Information System (INIS)

... excitation experimental data gamma radiation mev range 01-10 parity

International Nuclear Information System (INIS)

We consider a particle that is subject to a constant force and scatters inelastically on a vibrating periodically corrugated floor. At small friction and for small scatterers the dynamics is dominated by resonances forming spiral structures in phase space. These spiral modes lead to pronounced maxima and minima in the diffusion coefficient as a function of the vibration frequency, as is shown in computer simulations. Our theoretical predictions may be verified experimentally by studying transport of single granular particles on vibratory conveyors.

International Nuclear Information System (INIS)

Boron/aluminum skins and channels were used in the fabrication of a prototype honeycomb sandwich avionics shelf. The avionic shelves are stiffness-critical and must be vibration tolerant. In conjunction with the shelf mounting system, they must isolate the avionics equipment from the severe vibration of the primary and secondary structure nearby. Design rationale, fabrication procedures, vibration test criteria and test results are presented. (9 fig) (U.S.).

British Library Electronic Table of Contents (United Kingdom)

A 60-year-old male was bitten by a venomous snake (Vipera ammodytes) and gradually developed signs of an allergic reaction including generalized itching, generalized rash, and chest discomfort. This was followed by severe retrosternal pain with electrocardiographic evidence of an inferior myocardial ischemia progressing to acute myocardial infarction. Cardiac enzymes and troponin, serum tryptase, and histamine were elevated. Coronary arteriography showed normal coronary arteries. This is a characteristic type I variant of Kounis syndrome, which is the concurrence of acute coronary syndromes with conditions associated with mast cell activation including allergic or hypersensitivity reactions as well as anaphylactic or anaphylactoid reactions. This is the first report to show that viper bite...

International Nuclear Information System (INIS)

Differential scattering experiments are reported for proton impact on N_2, CO, and NO in the energy range E/sub lab/=30--80 eV. The measurements include the range of very small scattering angles around 0"0 as well as the rainbow region. The vibrationally resolved energy-loss spectra show a relatively low vibrational inelasticity for all three systems. Differential cross sections, transition probabilities, and the mean vibrational energy transfer are presented. Rotational excitation is indicated by the broadening of the energy-loss peaks which is most significant for H"+--NO. The small-angle scattering data for vibrational excitation in CO show good agreement with the impact parameter theory using the known long-range interactions for this system.

Science.gov (United States)

A six-axis active vibration isolation system (AVIS) is designed by using the direct driven guide and ball contact mechanisms in order to have no cross-coupling between actuators. The point contact configuration gives an advantage of having an easy assembly of eight voice coil actuators to an upper and a base plate. A voice coil actuator is used since it can provide a large displacement and sufficient bandwidth required for vibration control. The AVIS is controlled considering the effect of flexible vibration mode in the upper plate and velocity sensor dynamics. A loop shaping technique and phase margin condition are applied to design a vibration controller. The performances of the AVIS are investigated in the frequency domain and finally validated by comparing with the passive isolation system. The scanning profiles of the specimen are compared together by using the atomic force microscope. The ...

International Nuclear Information System (INIS)

Larsen syndrome is an autosomal-dominant disorder characterized by multiple joint dislocations, vertebral anomalies and dysmorphic facies. Both autosomal-dominant and autosomal-recessive forms of the disorder have been proposed. Individuals with autosomal-dominant Larsen syndrome have characteristic ''cylindrical-shape'' thumbs caused by broad, shortened phalanges. Autosomal-dominant Larsen syndrome results from heterozygosity for mutations in filamin B, a cytoskeletal protein involved in multicellular processes. We report here a patient with a duplicated or accessory distal thumb phalanx and multiple large joint dislocations who was shown to be heterozygous for a filamin B mutation predicting the amino acid substitution G1691S. This adds a new radiographic finding, duplicated or accessory distal phalanx, to the radiographic abnormalities seen in this rare dominant disorder. (orig.)

International Nuclear Information System (INIS)

Portuguese 1984. p. 147. Brazil Accursio, WJ Vieira, JGH Kater, CE Chacra,

UK PubMed Central (United Kingdom)

ObjectiveNeuralgic amyotrophy (NA) is a distinct clinical syndrome that is characterized by the acute onset of shoulder and arm pain, weakness, and sensory loss. The purpose of this...Full Text Available

UK PubMed Central (United Kingdom)

Although the cause and development of most inflammatory and fibrotic interstitial lung diseases are unknown, both the antigenic stimuli and the immunopathogenic mechanisms that produce the syndrome...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundMutations that disrupt the conversion of prelamin A to mature lamin A cause the rare genetic disorder Hutchinson-Gilford progeria syndrome and a group of laminopathies....Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Aims.- To examine the relationships between depression, coronary artery disease, type 2 diabetes, metabolic syndrome and quality of life in Taiwanese adults from a cardiovascular department of a major hospital in Taiwan. Background.- Research suggests associations between depression, metabolic syndrome and quality of life. Despite this fact, few studies have investigated these relationships among Taiwanese. Design.- A cross-sectional descriptive correlational design was used to conduct this study. Methods.- A convenience sample of 140 adults participated in the study. Data were analysed with descriptive statistics, Pearson-s correlations, hierarchical regression and t-tests. Results.- Almost a half of the subjects (465%) had metabolic syndrome. The most common combination of metabolic synd...

UK PubMed Central (United Kingdom)

Prolonged disability is best understood as an illness that exists independently of the initiating disease. The disabled individual goes through predictable stages of disability before resolution occurs....Full Text Available

UK PubMed Central (United Kingdom)

Snakebite envenomation is an uncommon condition in the northern hemisphere, but requires high vigilance with regard to both the systemic effects of the venom and the locoregional impact on the soft...Full Text Available

UK PubMed Central (United Kingdom)

Hereditary hyperferritinemia cataract syndrome (HHCS) is a rare condition caused by mutations in the gene coding for the light chain of ferritin; it does not lead to iron overload, but it is associated...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Vibration signature analysis has been commonly used for the machine condition monitoring and the control of errors. However, it has been rarely employed for the analysis of the precision instruments such as an atomic force microscope (AFM). In this work, an AFM was used to collect vibration data from a sample positioning stage under different suspension and support conditions. Certain structural characteristics of the sample positioning stage show up as a result of the vibration signature analysis of the surface height images measured using an AFM. It is important to understand these vibration characteristics in order to reduce vibrational uncertainty, improve the damping and structural design, and to eliminate the imaging imperfections. The choice of method applied for vibration analysis may affect the results. Two methods, the data dependent systems (DDS) ...

Energy Technology Data Exchange (ETDEWEB)

We numerically constructed elementary phase-correct global quantum gates by using molecular electronic and vibrational states to encode two qubits and implement the Deutsch-Jozsa algorithm. The calculations were based on optimal control theory (OCT). The molecular species we chose were Na{sub 2} and Li{sub 2}. The electronic X{sup 1}{sigma}{sub g}{sup +} and A{sup 1}{sigma}{sub u}{sup +} states were taken as two orthonormalized energy levels of the electronic qubit. The vibrational qubits were those involved in these electronic states. The time duration of the optimized pulses with high fidelity was typically 500-900 fs, which reflects the wavepacket dynamics in electronically ground and excited states. When implementing the Deutsch-Jozsa algorithm by combining these elementary gates, we obtained a maximum probability 83.12% for Li{sub 2} molecule, which indicates that the electronic-vibrational qubits are worse than the ...

UK PubMed Central (United Kingdom)

Werner syndrome (WS) is a rare disorder characterized by the premature onset of several pathologies associated with aging. The gene responsible for WS codes for a RecQ-type DNA helicase and is believed...Full Text Available

International Nuclear Information System (INIS)

Klippel-Feil Syndrome (KFS) is a congenital anomaly characterized by a defect in the formation or segmentation of the cervical vertebrae. The clinical triad consists of short neck, low posterior hairline and limited neck movement. Multiple congenital anomalies have been associated with this disease. This is a case of KFS in a young girl along with situs inversus, which is an extremely rare association. Various systemic associations occurring in this multi-system disorder are also discussed. (author)

UK PubMed Central (United Kingdom)

Background:Acute Coronary Syndrome (ACS) can occur in patients with prior coronary artery bypass grafting (CABG). In the Gulf Registry of acute coronary events (Gulf RACE), we identified...Full Text Available

UK PubMed Central (United Kingdom)

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) remains an enigmatic medical condition. Creation of the (NIH) Chronic Prostatitis Collaborative Research Network (CPCRN) funded by...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This report describes development of an electronic system designed to reduce vibration generated by a cryocooler. The diminished vibration makes it practical to use the active cooler to extract heat from a portable gamma ray detector instrument. The system was developed for a Sunpower cryocooler with an integrated counterbalance mass. The overall momentum cancellation approach is also applicable to other similar cryocoolers. The cancellation system is an assembly of several components tailored to accomplish the required vibration reduction with minimum power consumption and volume. It is designed to be powered by a 18--32 Volt battery. Up to ten harmonics of the 58.65 Hz drive frequency are controlled. In addition to the vibration cancellation, the electronic system produces the drive signal for the cryocooler and regulates the cooler temperature. The system employs a sinusoidal drive to reduce the ...

International Nuclear Information System (INIS)

In the present study, a subcooled boiling loop with an annular flow on the electrically heated rod was used to make an experimental approach to investigate the effects of induced instability by the subcooled boiling on vibration of the rod in different subcooled conditions. The results show the intensive subcooled-boiling-induced vibration (SBIV) which is highly depend on dynamic force generated by fast vapor bubbles growth and collapse whilst they still attach to, or slide along, the heating surface at high loading heat fluxes. These behaviors were strongly influenced by the conditions of subcooling temperature, flow rate and linear power density. (author)

International Nuclear Information System (INIS)

By methods of vibrational (infrared, Raman) and PMR spectroscopy, crystallohydrate forms of monosubstituted uranyl orthophosphate have been examined. The vibrational frequencies of the groupings from the compounds were identified. The existence of non-equivalent H_2PO_4"--groups in the substances under investigation was ascertained. It has been suggested that one of them is a bridged group, and the other is the end group. A fragment of the VO_2(H_2PO_4)_2 hydrate structure is given, its main constituents being uranylphosphate chains. The analysis of water vibrations assumes coordination of one mole of H_2O in VO_2(H_2PO_4)_2:3H_2O to uranium, while two other molecules are only hydrogen-bonded with phosphate anions. Absorption within the region of 2100-2550 cm"-"1 is assigned to vibrations of O...H...O groupings.

Energy Technology Data Exchange (ETDEWEB)

There is a clear incentive, therefore, for early consideration of the measures required to meet noise and vibration standards. The platform or rig owner and the operator are jointly responsible for agreeing a noise and vibration control policy and approach at the conceptual design stage, and for then passing on their requirements to the engineering design teams. The engineering design teams and acoustic and vibration specialists for their part need to use all their skill and judgement to apply that policy to the intensely complex job of designing and fabricating topsides facilities. With these concerns as background, UEG started, and has nearly completed, a two-phase study to provide detailed guidance to project managers and designers to assist them to develop appropriate policy and procedures and to help them put those procedures into practice. This paper describes the development of UEG's study, its application ...

Science.gov (United States)

... being designed for projected Minotaur IV launch load environments, with design objectives of light weight, integrated vibration isolation, low shock ...

International Nuclear Information System (INIS)

Flow-induced vibration is an important concern to the designers of heat exchangers subjected to high flows of gases or liquids. Two-phase cross-flow occurs in industrial heat exchangers, such as nuclear steam generators, condensers, and boilers, etc. Under certain flow regimes and fluid velocities, the fluid forces result in tube vibration and damage due to fretting and fatigue. Prediction of these forces requires an understanding of the flow regimes found in heat exchanger tube bundles. Excessive vibrations under normal operating conditions can lead to tube failure. Relatively little information exists on two-phase vibration. This is not surprising as single-phase flow induced vibration; a simpler topic is not yet fully understood. Vibration in two-phase is much more complex because it depends upon two-phase flow regime, i.e. characteristics of two-phase ...

British Library Electronic Table of Contents (United Kingdom)

Abstract Sudden infant death syndrome (SIDS) is always a devastating and unexpected occurrence. SIDS is the leading cause of death in the first 6 months after birth in the industrialized world. Since the discovery in 1998 of long QT syndrome as an underlying substrate for SIDS, around 10-20% of SIDS cases have been proposed as being caused by genetic variants in either ion channel or ion channel-associated proteins. Until now, 10 cardiac channelopathy susceptibility genes have been found to be implicated in the pathogenesis of SIDS. Four of the genes encode cardiac ion channel a-subunits, 3 genes encode ion channel b-subunits, and 3 genes encode other channel-interacting proteins. All 10 genes have been associated with primary electrical heart diseases. SIDS may hereby be the initial sympt...

International Nuclear Information System (INIS)

It is shown that low-frequency elastic vibrations of near-surface planar defects cause high-frequency ultrasonic radiation in surrounding air. The frequency conversion mechanism is concerned with contact nonlinearity of the defect vibrations and provides efficient generation of air-coupled higher-order ultraharmonics, ultrasubharmonics, and combination frequencies. The nonlinear air-coupled ultrasonic emission is applied for location and high-resolution imaging of damage-induced defects in a variety of solid materials.

Energy Technology Data Exchange (ETDEWEB)

Fast Test Reactor core internal and peripheral components were assessed for flow-induced vibrational characteristics under scaled and simulated prototype flow conditions in the Hydraulic Core Mockup as an integral part of the Fast Test Reactor Vibration Program. The Hydraulic Core Mockup was an 0.285 geometric scale model of the Fast Test Reactor internals designed to simulate prototype vibrational and hydraulic characteristics. Using water to simulate sodium coolant, vibrational characteristics were measured and determined for selected model components over the scaled flow range of 36 to 110%. Additionally, in-situ shaker tests were conducted on selected Hydraulic Core Mockup outlet plenum components to establish modal characteristics. Most components exhibited resonant response at all test flow rates; however, the measured dynamic response was neither abnormal nor anomalously flow-rate dependent, and ...

Energy Technology Data Exchange (ETDEWEB)

This is a prompt report. These days the importance of acquiring knowledge about the structure from the lower crust down to the upper mantle is often discussed with reference taken to Hyogo-ken Nanbu Earthquake. The Hidaka collision belt where the lower crust is exposed on the surface is a rare phenomenon in the world and has been the subject of seismic survey. As a part of the survey, experiments are conducted by the use of vibrations produced by Vibroseis and dynamite sources. Every one of the shot records (20-second record) from the two types of vibration sources contains a clear echo in the vicinity of 16 seconds supposedly from a level deeper than 40 kilometers, not to mention reflections from shallow levels. Although some studies have to be conducted before the reflecting geological boundary (possibly the upper mantle) of the echo near the 16-second point can be identified, yet this is probably the reflection from the deepest level ever ...

UK PubMed Central (United Kingdom)

Atypical hemolytic uremic syndrome (aHUS) is a heterogeneous disease that is caused by defective complement regulation in over 50% of cases. Mutations have been identified in genes encoding both complement...Full Text Available

UK PubMed Central (United Kingdom)

Of 107 women investigated for frequency of micturition and dysuria, 21 had gonorrhoea, 14 chlamydial urethritis, eight an Escherichia coli urinary tract infection, 18 candidosis, 12 trichomoniasis,...Full Text Available

UK PubMed Central (United Kingdom)

A ten week old girl who had previously undergone a palliative procedure for the hypoplastic left heart syndrome had unrelieved aortic coarctation that did not respond to standard balloon dilatation....Full Text Available

UK PubMed Central (United Kingdom)

FRAXA is one of a number of fragile sites in human chromosomes that are induced by agents like fluorodeoxyuridine (FdU) that affect intracellular thymidylate levels. FRAXA coincides with a >200...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundCharacterizing infectious disease burden in Africa is important for prioritizing and targeting limited resources for curative and preventive services and monitoring the...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe study of small airway diseases such as post-transplant bronchiolitis obliterans syndrome (BOS) is hampered by the difficulty in assessing peripheral airway function...Full Text Available

UK PubMed Central (United Kingdom)

Excessive weight loss due to protein calorie malnutrition (PCM) is a significant problem in Nigerian children. This syndrome may be difficult to differentiate from the wasting disease caused by human...Full Text Available

UK PubMed Central (United Kingdom)

We have recently reported that progeroid Zmpste24^−/− mice, which exhibit multiple defects that phenocopy Hutchinson-Gilford progeria syndrome, show a profound dysregulation...Full Text Available

UK PubMed Central (United Kingdom)

Treatment of functional bowel disorders of irritable bowel-type (IBS) in children remains a difficult task because of a lack of drugs with low adverse event profile. We here report the results of a...Full Text Available

UK PubMed Central (United Kingdom)

Severe pericardial effusion is a rare complication of bacterial pneumonia and it usually disappears under medical treatment. Herein we report a case of a girl with a congenital immunodeficient syndrome...Full Text Available

UK PubMed Central (United Kingdom)

PURPOSE: To determine the frequency of ophthalmic abnormalities in patients with cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome) and T-cell lymphoma involving the skin and...Full Text Available

Science.gov (United States)

PMID:11835026

UK PubMed Central (United Kingdom)

Dysregulation of the alternative pathway of complement activation, caused by mutations or polymorphisms in the genes encoding factor H, membrane co-factor protein, factor I or factor B, is associated...Full Text Available

International Nuclear Information System (INIS)

A 30-year-old man with acquired immune deficiency syndrome (AIDS) and Kaposi's sarcoma had a palpable thyroid mass and cervical lymphadenopathy. Nuclear medicine and ultrasound scans revealed multiple thyroid nodules. Results of biopsy showed Kaposi's sarcoma metastatic to the thyroid.

UK PubMed Central (United Kingdom)

BackgroundWe have recently reported successful treatment of patients with chronic pain syndromes using human pooled intravenous immunoglobulin (IVIG) in a prospective, open-label...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis is a rare entity, sometimes referred to as Herlyn-Werner-Wunderlich syndrome (HWW). It usually presents after menarche with progressive pelvic pain, sometimes with regular menses, and a palpable mass due to hemihaematocolpos. The diagnosis is generally made only if the suspicion of this genitourinary syndrome is raised. To highlight the imaging diagnostic clues in this rare condition. We report on 11 adolescents with this condition. Sonography mostly allowed the correct diagnosis by showing uterovaginal duplication, haematocolpos or haematometrocolpos, and the absence of the ipsilateral kidney. MRI provided more detailed information regarding uterine morphology, the continuity with each vaginal channel (obstructed and nonobstructed), and the bloody nature of the contents. Early and accurate diagnosis of this syndrome is important so that adequate and ...

UK PubMed Central (United Kingdom)

Patients treated with bleomycin are at risk of developing the acute adult respiratory distress syndrome post-operatively. In a prospective study of 12 patients who had received bleomycin preoperatively...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundSeven genes involved in folate metabolism are located on chromosome 21. Previous studies have shown that folate deficiency may contribute to mental retardation in Down's...Full Text Available

UK PubMed Central (United Kingdom)

Carney-Stratakis syndrome, an inherited condition predisposing affected individuals to gastrointestinal stromal tumor (GIST) and paraganglioma, is caused by germline mutations in succinate dehydrogenase...Full Text Available

UK PubMed Central (United Kingdom)

The symptoms of two patients with bilateral cortical auditory lesions evolved from cortical deafness to other auditory syndromes: generalised auditory agnosia, amusia and/or pure word deafness, and...Full Text Available

UK PubMed Central (United Kingdom)

Shilajit has been used traditionally in folk medicine for treatment of a variety of disorders, including syndromes involving excessive complement activation. Extracts of Shilajit contain significant...Full Text Available

UK PubMed Central (United Kingdom)

IntroductionColonoscopic perforation is a rare but serious complication of colonoscopy. Factors known to increase the risk of perforation include colonic strictures, extensive diverticulosis,...Full Text Available

UK PubMed Central (United Kingdom)

Germ cell tumor development in humans has been proposed to be part of testicular dysgenesis syndrome (TDS), which manifests as undescended testes, sterility, hypospadias, and, in extreme cases,...Full Text Available

Science.gov (United States)

Effectiveness Flu Shot Nasal Spray Vaccine (LAIV) Thimerosal Guillain-Barré Syndrome (GBS) Antiviral Drugs: Key Facts Antiviral Drugs: Q&A Antiviral Drug Resistance Links,...

UK PubMed Central (United Kingdom)

Forty children with the fetal alcohol syndrome were identified in the west of Scotland. All were growth retarded and had abnormal facial features, and all those who were tested were found to have neurological...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundObesity is one of the principal causative factors involved in the development of metabolic syndrome. AMP-activated protein kinase (AMPK) is an energy sensor that regulates...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveThe goal of the study was to investigate the genetic and molecular basis of a novel syndrome of marked hyperglucagonemia and pancreatic α cell hyperplasia...Full Text Available

UK PubMed Central (United Kingdom)

The global acquired immunodeficiency syndrome (AIDS) pandemic is thought to have arisen by the transmission of human immunodeficiency virus (HIV-1)-like viruses from chimpanzees in southeastern...Full Text Available

Science.gov (United States)

Eliminating anterior tooth contact is paramount when treating combination syndrome. It is possible to do so through the use of linear occlusion with a non-interceptive arrangement and the bilateral fulcrum of protrusive stability. The presence of mandibular anterior teeth often complicates this procedure. When establishing the horizontal plane of occlusion, clinical circumstances often necessitate modifications; nevertheless, certain principles must be incorporated into the design of the prostheses. Clinical circumstances may dictate altering the approach but these principles must be maintained to eliminate anterior hyperfunction. PMID:15055634

Energy Technology Data Exchange (ETDEWEB)

Thirty-two patients with AIDS related complex (ARC) or acquired immunodeficiency syndrome (AIDS) underwent /sup 67/Ga scans as part of their evaluation. Three patterns of /sup 67/Ga biodistribution were found: lymph node uptake alone; diffuse pulmonary uptake; normal scan. Gallium-67 scans were useful in identifying clinically occult Pneumocystis carinii pneumonia in seven of 15 patients with ARC who were asymptomatic and had normal chest radiographs. Gallium scans are a useful ancillary procedure in the evaluation of patients with ARC or AIDS.

British Library Electronic Table of Contents (United Kingdom)

Visceral hypersensitivity is currently considered a key pathophysiological mechanism involved in pain perception in large subgroups of patients with functional gastrointestinal disorders, including irritable bowel syndrome (IBS). In IBS, visceral hypersensitivity has been described in 20%?90% of patients. The contribution of the central nervous system and psychological factors to visceral hypersensitivity in patients with IBS may be significant, although still debated. Peripheral factors have gained increasing attention following the recognition that infectious enteritis may trigger the development of persistent IBS symptoms, and the identification of mucosal immune, neural, endocrine, microbiological, and intestinal permeability abnormalities. Growing evidence suggests that these factors ...

British Library Electronic Table of Contents (United Kingdom)

Environmental tobacco smoke (ETS), containing the developmental neurotoxicant, nicotine, is a prevalent component of indoor air pollution. Despite a strong association with active maternal smoking and sudden infant death syndrome (SIDS), information on the risk of SIDS due to prenatal and postnatal ETS exposure is relatively inconsistent. This literature review begins with a discussion and critique of existing epidemiologic data pertaining to ETS and SIDS. It then explores the biologic plausibility of this association, with comparison of the known association between active maternal smoking and SIDS, by examining metabolic and placental transfer issues associated with nicotine, and the biologic responses and mechanisms that may follow exposure to nicotine. Evidence indicates that prenatal ...

International Nuclear Information System (INIS)

Crystalline Pd_9Si_2 possesses an orthorhombic structure (Pnma) that is characterized by augmented triangular prismatic coordination of the silicon atoms such as that which occurs in several metal-rich transition-metal silicides. Recent neutron diffraction results for deuterium solution in this crystalline phase have indicated that deuterium occupies only one type of interstice, i.e., a Pd-defined pyramidal site in a four-fold position situated on a quadrilateral face of an empty triangular prism. The vibrational dynamics of both H and D located at this site were investigated by neutron vibrational spectroscopy. The low-temperature density of states (DOS) of H in Pd_9Si_2H_0_._2_5 indicates three well-defined optic vibrations located at 49.4, 67.2 and 75.5 meV. The lowest-energy feature is assigned to the normal-mode vibration perpendicular to the pyramidal base and the two higher-energy features are ...

British Library Electronic Table of Contents (United Kingdom)

The generalized demodulation time-frequency analysis is a novel signal processing method, which is particularly suitable for the processing of multi-component amplitude-modulated and frequency-modulated (AM-FM) signals as it can decompose a multi-component signal into a set of single-component signals whose instantaneous frequencies own physical meaning. While fault occurs in gear, the vibration signals measured from gearbox would exactly display AM-FM characteristics. Therefore, targeting the modulation feature of gear vibration signal in run-ups and run-downs, a fault diagnosis method in which generalized demodulation time-frequency analysis and envelope order spectrum technique are combined is put forward and applied to the transient analysis of gear vibration signal. Firstly the multi-...

International Nuclear Information System (INIS)

A series of Model Tests of Embedment Effect on Reactor Buildings has been carried out by the Nuclear Power Engineering Corporation (NUPEC), under the sponsorship of the Ministry of International Trade and Industry (MITI) of Japan. Sinusoidal forced vibration tests were carried out on three types of large-scale models to study the embedment effect on dynamic soil-structure interaction. The differences in the resonance curves and the impedance functions were discussed in relation to the vibration characteristics of the respective structures. The embedment effects on the structural responses vary according to the stiffness of the structure. The responses of the structures can be evaluated by the Axisymmetric FEM analyses. (author)

Energy Technology Data Exchange (ETDEWEB)

In order to suppress resonance vibrations of a rotor-shaft of rotating machinery, a rotor-shaft system elastically supported by ball bearings which are installed in electromagnetic actuators are proposed and the design method of some compensatory circuits in the controller to control the electromagnetic actuators in the system are explained. These actuators are controlled by the analog PID (proportional, integral, and derivative) controller. The compensation for nonlinearity of electromagnetic force, the negative stiffness of electromagnet, and the time lag of the coil current are discussed and the effective control circuits are proposed. The rotor-shaft system is replaced by the equivalent two-degree-of-freedom system and both impulse and frequency responses are numerically simulated for several parameters of PD-controller gain. By applying the principle of dynamic absorbers, optimum parameters are calculated. The gains of the control circuit are adjusted to give ...

British Library Electronic Table of Contents (United Kingdom)

Varying load can cause changes in a measured gearbox vibration signal. However, conventional techniques for fault diagnosis are based on the assumption that changes in vibration signal are only caused by deterioration of the gearbox. There is a need to develop a technique to provide accurate state indicator of gearbox under fluctuating load conditions. This paper presents an approach to gear fault diagnosis based on complex Morlet continuous wavelet transform under this condition. Gear motion residual signal, which represents the departure of time synchronously averaged signal from the average tooth-meshing vibration, is analyzed as source data due to its lower sensitiveness to the alternating load condition. A fault growth parameter based on the amplitude of wavelet transform is proposed ...

Energy Technology Data Exchange (ETDEWEB)

In this experiment, a beam incident from an oblique direction is reflected by a spherical lens toward the direction of incidence. When the surface of a matter is vibrated by elastic waves, the spherical lens comes into a translation motion that accompanies the vibration. It follows accordingly that the vibration on the surface of the matter may be detected by sensing the spherical lens travelling speed. Three components of the vibration may be determined if beams are focused at one spot from three directions. Detection of the S-wave component by LDV (laser Doppler vibrometer) discloses the complicated wave field in a heterogeneous material, and this physical model experiment may be utilized in various fields of study. For instance, information about problems that may surface in the field work may be collected beforehand in a physical model experiment for developing an S-wave-aided probing method. For ...

UK PubMed Central (United Kingdom)

Despite prolonged scientific efforts to unravel the hydration structures of ions in water, many open questions remain, in particular concerning the existences and structures of ion clusters in 1∶1...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Interference between the crossover leg of the Reactor Coolant System(RCS) and the Pipe Whip Restraints(PWR) has brought a degradation issue of the integrity of the Reactor Coolant System in Westinghouse type Nuclear Power Plants(NPPs) of Korea. According to the gap inspection carried out during planned overhaul (year 2000), interference between the crossover leg and the PWR was found in each RCS loop. This plant has had the high vibration problem on the RC pump 'B'. The reason for the high vibration in the RC pump 'B' had been massively surveyed and it was found that the crossover leg of RCS contacted with the PWR in hot condition. Since the contact between the crossover leg and the PWR changes the dynamic characteristics of the piping system for the RCS, this is considered as one reason for the high vibration. And a possibility of overstress on the crossover leg due to the contact with ...

Science.gov (United States)

Page 1. Page 2. Page 3. Page 4. Page 5. Page 6. Page 7. Page 8. Page 9. Page 10. Page 11. Page 12. Page 13. Page 14. Page 15. Page 16. Page ...

Science.gov (United States)

Varying load can cause changes in a measured gearbox vibration signal. However, conventional techniques for fault diagnosis are based on the assumption that changes in vibration signal are only caused by deterioration of the gearbox. There is a need to develop a technique to provide accurate state indicator of gearbox under fluctuating load conditions. This paper presents an approach to gear fault diagnosis based on complex Morlet continuous wavelet transform under this condition. Gear motion residual signal, which represents the departure of time synchronously averaged signal from the average tooth-meshing vibration, is analyzed as source data due to its lower sensitiveness to the alternating load condition. A fault growth parameter based on the amplitude of wavelet transform is proposed to evaluate gear fault advancement quantitatively. We found that this parameter is insensitive to varying load and can correctly indicate ...

International Nuclear Information System (INIS)

The puborectalis syndrome is a defecation disorder supported by the nonrelaxation of puborectalis sling with consequent dyschezia. They report on a series of 98 patients submitted to clinical examination, defecography, anorectal manometry, electromyography and intestinal transit time studies. The main symptoms of puborectalis syndrome in their patients were incomplete defecation (89 %) and intermittent evacuation (63 %); 28 % of patients turned to finger defecation. In all patients, defecography showed an abnormal increase in puborectalis impression on the posterior anorectal wall, reduced anorectal angle opening under straining (mean value: 113 deg) and prolonged expulsion time with barium pooling in the ampulla (mean evacuation time: 38 seconds). Such anorectal abnormalities as rectal mucosal prolapse (47 cases) and anterior rectocele (36 cases) were also associated. In 33 of 98 patients (34 % of cases), sling assessment by bidigital ...

Science.gov (United States)

An exact solution method for the free vibration problem of thin circular cylindrical shells is presented. The differential equations of motion are solved directly with the use of simple Fourier series as the modal displacement functions. Stokes' transformation is exploited to obtain correct series expressions for the derivatives of the Fourier series. From this method an explicit expression of the exact frequency equation can be obtained for any kind of boundary conditions. The accuracy of the present method is checked against available data. The proposed method is then used to find the modal characteristics of the thermal liner of the Fast Test Reactor (FTR). The numerical results obtained are compared with finite element method solutions. (auth)

Energy Technology Data Exchange (ETDEWEB)

A device is presented with handle containing hinges and work support arm, a flexible pin with supports and extra weights. The flexible pin is equipped with cantilevered sergments and weights. The bracket hinges on the handle are perpendicular to the axis of the flexible pin. To reduce handle vibration during drilling hard rock, the handle and brackets are joined to allow relative movement on the surface perpendicular to the hinges of the work support arm. The handle is joined to the work support arm parallel to the sides and the work support arm has holes to accomodate this. Elastic bushings are located between the lateral sides of the work support arm where it is joined to the handle.

International Nuclear Information System (INIS)

Monitoring and diagnostic systems are of main importance for a safe and efficient operation of nuclear power plants. The author describes new developments with respect to vibration monitoring with a functional extension in the time domain for den secondary circuit, the development of a local system for the surveillance of rotating machines, the structure-borne sound monitoring with improvement of event analysis, esp. the loose part locating, leakage monitoring with a complete system for humidity measurement, and the development of a common platform for all monitoring and diagnostic systems, that allows an efficient access for comparison and cross references.

Energy Technology Data Exchange (ETDEWEB)

17 papers are presented. Topics covered include: the POG system - a new concept in the use of ANFO; demolition of a motorway bridge; presplit and smooth blasting; VIBReX - a predictive code for assessing the effect of blast design on ground vibration; ground vibrations from blasting; digital seismographs; human response to blasting and the effects on planning conditions; landform construction by restoration blasting; use of small diameter explosives; efficient priming; safety management in the explosives industry; and the law on packaging of explosives. Two papers have been abstracted separately.

International Nuclear Information System (INIS)

A dispersion interferometer based on CO2 laser for measurements of plasma line density in the gas dynamic trap (GDT) experiment has been developed with sensitivity el>min ? 1.1013 cm-2, temporal resolution ?50 ns. The main advantages of the interferometer are compactness and low sensitivity to vibrations. The interferometer does not require specific vibration isolation structure and can be mounted directly on the working chamber of the plasma device. The above mentioned advantages have been successfully demonstrated in the Gas Dynamic Trap experiments.

CERN Document Server

A discrete time control algorithm using the damped least squares is introduced for acceleration and energy exchange controls in nonlinear vibrating systems. It is shown that the damping constant of least squares and sampling time step of the controller must be inversely related to insure that vanishing the time step has little effect on the results. The algorithm is illustrated on two linearly coupled Duffing oscillators near the 1:1 internal resonance. In particular, it is shown that varying the dissipation ratio of one of the two oscillators can significantly suppress the nonlinear beat phenomenon.

International Nuclear Information System (INIS)

The survival time of golden hamsters (Mesocricetus auratus) after whole-body "6"0Co-#gamma#-irradiation in the range of 600 to 200 000 rad was investigated. The two plateaus of the dose-survival curve which correspond to bone marrow and gastrointestinal death are similar to those of other species such as mice, rats and mongolian gerbils. A new plateau occurring 40-57 hours after doses of 30 000-60 000 rad, where there is a little reduction in survival time, has been found. It is in addition to the well recognized central nervous system (CNS) syndrome. This plateau is observed only in golden hamsters, presumably because of their relatively high resistance to CNS syndrome. Experiments involving partial body irradiation of the animals indicate that the target is in the cephalic one-third of abdomen. The new segment may well indicate a new type of acute somatic radiation injury different from the well known bone marrow, gastrointestinal and CNS ...

British Library Electronic Table of Contents (United Kingdom)

Objective To investigate the impact on life quality of women with traumatic and non-traumatic origin fibromyalgia syndrome [FMS]. Method Women affected with FMS were selected and divided into two groups: those with traumatic origin FMS [Group 1] and those with non-traumatic origin FMS [Group 2]. A standard question form was used for the research, as well as the fibromyalgia impact questionnaire [FIQ] for evaluation of life quality. Results Seventy-two patients, 34 for Group 1 and 38 for Group 2 were analyzed. The main triggering symptoms were divorce [23.5 percent of cases] and death in the family [23.5 percent of cases]. In addition to diffuse pain, the main symptoms presented were poor sleep quality, weariness, and paresthesia, with no difference between the groups; migraine had a greate...

British Library Electronic Table of Contents (United Kingdom)

Abstract Aims: The aim of this study was to examine whether metabolic syndrome (MS) is associated with periodontitis in a representative sample of Korean adults, who were involved in the Fourth Korea National Health and Nutrition Examination Survey (KNHANES). Materials and Methods: A total of 7178 subjects over the age of 19 years who participated in KNHANES were examined. MS was defined as the definition proposed by the National Cholesterol Education Program Adult Treatment Panel III and the abdominal obesity cut-off line based on Korean Society for the Study of Obesity. The periodontal status was assessed by the Community Periodontal Index. Multivariate logistic regression analysis was carried out adjusting for the sociodemographics, oral health behaviours and status, and health behaviou...

British Library Electronic Table of Contents (United Kingdom)

BACKGROUNDLifestyle modifications are successfully employed to treat obese and overweight women with polycystic ovary syndrome (PCOS). The aims of the current pilot study were (i) to compare the efficacy on reproductive functions of a structured exercise training (SET) programme with a diet programme in obese PCOS patients and (ii) to study their clinical, hormonal and metabolic effects to elucidate potentially different mechanisms of action.METHODSForty obese PCOS patients with anovulatory infertility underwent a SET programme (SET group, n = 20) and a hypocaloric hyperproteic diet (diet group, n = 20). Clinical, hormonal and metabolic data were assessed at baseline, and at 12- and 24-week follow-ups. Primary endpoint was cumulative pregnancy rate.RESULTSThe two groups had similar demogra...

British Library Electronic Table of Contents (United Kingdom)

We investigated the presence of XMRV in a cohort of Quebec patients with chronic fatigue syndrome (CFS). DNA was purified from activated peripheral blood mononuclear cells (PBMCs) and PCR was used to detect XMRV gag and env in 72 patients. Anti-XMRV antibodies were searched in sera of 62 patients by Western blot analysis. Attempts to detect XMRV antigens was made, using immunofluorescence with Gag anti-p30 antiserum on activated PBMC from 50 patients. Plasma viremia was measured by RT-PCR on 9 subjects. Finally, detection of infectious virus in 113 CFS subjects was made by co-culture of PHA+IL-2 activated PBMC with human LNCaP carcinoma cells, and by infecting the same susceptible cells with plasma, using a reverse transcriptase (RT) assay as a readout in both experiments. No detection of ...

Science.gov (United States)

From May, 1999 to August, 2006, we performed laparoscopic diagnosis and treatment for 103 cases of impalpable testes. Among those we found 5 cases of male pseudohermaphroditism of different etiologies. Three males presented by impalpable testes with ambiguous genitalia and 2 females presented by primary amenorrhea. All of them have 46-XY normal male chromosomal pattern. In the first 3 cases, the etiology was complete gonadal dysgenesis, and 2 cases with persistent Mullerian syndrome. Timed gonadectomy for the first case and laparoscopic orchiopexy for the other 2 cases were performed. For the other 2 female cases, the etiology was complete androgen insensitivity syndrome and laparoscopic bilateral orchiectomy was performed for both of them. All the procedures were done without complications with satisfactory results. PMID:18319558

Energy Technology Data Exchange (ETDEWEB)

The Lesch-Nyhan (LN) syndrome is a severe X chromosome-linked disease that results from a deficiency of the purine salvage enzyme hypoxanthine phosphoribosyltransferase (HPRT). The mutations leading to the disease are heterogeneous and frequently arise as de novo events. The authors have identified nucleotide alterations in 15 independently arising HPRT-deficiency cases by direct DNA sequencing of in vitro amplified HPRT cDNA. They also demonstrate that the direct DNA sequence analysis can be automated, further simplifying the detection of new mutations at this locus. The mutations include DNA base substitutions, small DNA deletions, a single DNA base insertion, and errors in RNA splicing. The application of these procedures allows DNA diagnosis and carrier identification by the direct detection of the mutant alleles within individual families affected by LN.

British Library Electronic Table of Contents (United Kingdom)

ObjectiveTo address the characteristics of hearing loss in patients with Turner syndrome (TS), we evaluated hearing levels of patients with TS and analyzed causative factors.Study designThirty-three patients with TS (8 to 40 years of age) were studied through the use of audiological measurements, and causative factors were explored.ResultsTwenty cases (35 of 66 ears tested) showed high-frequency (8 kHz) sensory neural hearing loss (HFQ-SNHL). Fifteen cases (26 ears) and 15 cases (24 ears) of the impaired 20 cases were unresponsive to distortion-product otoacoustic emissions and transient-evoked otoacoustic emissions, respectively. HFQ-SNHL showed little relation to the history of middle ear infection and puberty, although middle ear infections were seen in 11 of the 20 cases. The hearing t...

British Library Electronic Table of Contents (United Kingdom)

Abstract Hereditary primary hyperparathyroidism (HPT) may develop as a solitary endocrinopathy (FIHP) or as part of multiple endocrine neoplasia Type 1, multiple endocrine neoplasia Type 2A, or hereditary HPT-jaw tumor syndrome. Inactivating germline mutations of the tumor suppressor gene CDC73 account for 14 and 50% of all FIHP and HPT-JT patients, respectively, and have also been found in almost 20% of apparently sporadic parathyroid carcinoma patients. Although more than 60 independent germline mutations have been described, to date no rearrangement affecting the CDC73 locus has been identified. By means of multiplex-PCR we found a large germline deletion affecting the whole gene in a two-generation HPT-JT family. Subsequently array-CGH and specific PCR analysis determined that the muta...

British Library Electronic Table of Contents (United Kingdom)

Immune thrombocytopenic purpura (ITP), Guillain-Barre syndrome (GBS), and Hashimotos thyroiditis (HT) are autoimmune disorders caused by impaired self-tolerance mechanisms triggered by interaction between genetic and environmental factors. ITP is an immune-mediated destruction of platelets resulting in mucocutaneous bleeding, GBS is an ascending motor paralysis caused by an inflammatory demyelination of peripheral nerves, and HT is characterized by autoimmune-mediated destruction of the thyroid gland. The concurrent development of ITP and GBS has only rarely been reported in the literature, and GBS itself rarely occurs with other autoimmune disorders. We present a 21 year-old patient with known Hashimotos hypothyroidism that simultaneously developed GBS and ITP after an upper respiratory t...

International Nuclear Information System (INIS)

Contrast agent-enhanced CT scans in nine male patients with histologically proved benign lymphoepithelial lesions of the perotid gland were reviewed. All scans showed cystic-appearing masses with peripheral rim enhancement corresponding to the macroscopic appearance of the lesion. Five patients were seropositive for human immunodeficiency virus (HIV) infection or had infections seen in acquired immunodeficiency syndrome. Three patients were members of high-risk groups. Only one patient had symptoms of the SICCA syndrome. Once a rare cause of parotid gland enlargement, benign lymphoepithelial lesions have recently been seen with increasing frequency in patients with HIV infection. Although the CT appearance is not pathognomic, correlation results of aspiration cytology and with clinical history can lead to a preoperative diagnosis of a benign lymphoepithelial lesion.

Energy Technology Data Exchange (ETDEWEB)

The human mitochondrial DNA (mtDNA) is a closed circular, 16,569-bp double-stranded DNA, encoding 13 genes whose protein products are subunits of the oxidative phosphorylation system required for synthesis of most of the ATP consumed by eukaryotic cells. Point mutations of the mtDNA that cause multi-tissue, loss-of-energy syndromes, called mitochondrial encephalomyopathies (e.g., MERRF and MELAS), have been identified. In addition, large-scale deletions of the human mtDNA have been identified and are the molecular bases for the neonatal and adolescent onset loss-of-energy syndromes Pearson and Kearns-Sayer, respectively. 5 refs., 1 fig.

Science.gov (United States)

The work reported in this paper is focused on an effective and efficient solution, namely Smart Isolation Mount for Army Guns (SIMAG), to the weapon stabilization and fire control issues facing US Army guns. SIMAG is composed of the optimum integration of two innovative technologies. Vibration Control by Confinement and smart senor/actuator/active control systems. The combined approach may also be applied to a gun barrel to reduce its undesired vibratory motions excited by external and internal disturbances, such as gun firing action. SIMAG reconfigures the distribution and propagation of excess vibration energy and confines vibrations to certain non-critical regions or modes within a structure. Concentrated passive, active, or smart damping elements or cancellation techniques may be applied to more effectively dissipate or cancel the trapped vibrations and to prevent build up in the assembly. As the ...

International Nuclear Information System (INIS)

The utility of recording Raman spectroscopy under liquid nitrogen, a technique we call Raman Under Nitrogen (RUN), is demonstrated for ferrocene, uranocene and thorocene. Using RUN, low temperature (liquid nitrogen cooled) Raman spectra for these compounds exhibit higher resolution than previous studies and new vibrational features are reported. The first Raman spectra of crystalline uranocene at 77 K are reported using excitation from argon (5145 ) and krypton (6764 ) ion lasers. The spectra obtained showed bands corresponding to vibrational transitions at 212, 236, 259, 379, 753, 897, 1500, and 3042 cm-1 , assigned to ring-metal-ring stretching, ring-metal tilting, out-of-plane CCC bending, in-plane CCC bending, ring-breathing, C-H bending, CC stretching and CH stretching, respectively. The assigned vibrational bands are compared to those of uranocene in THF and thorocene. All vibrational frequencies ...

UK PubMed Central (United Kingdom)

Background and ObjectivesClopidogrel resistance or low-responsiveness may be associated with recurrent atherothrombotic events after drug-eluting stent (DES) implantation. We prospectively...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundUsing a transcriptional profiling approach, we recently identified myeloid-related protein-8/14 (MRP-8/14) to be expressed by platelets during acute MI....Full Text Available

UK PubMed Central (United Kingdom)

To evaluate the reactivity of the recombinant proteins expressed in Escherichia coli strain BL21(DE3), a Western blot assay was performed by using a panel of 78 serum samples obtained,...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Inferior vena cava (IVC) obstruction is a well-described clinical entity. Most IVC obstructions from malignant neoplasms are a direct result of tumor compression [Oviedo J, Cerda S. Vascular invasion by hepatocellular carcinoma. Arch Pathol Lab Med 2001;125: 454-5; Furui S, Sawada S, et al. Gianturco stent placement in malignant caval obstruction: analysis of factors for predicting the outcome. Radiology 1995;195:147-52; Fletcher WS, Lakin PC, et al. Results of treatment of inferior vena cava syndrome with expandable metallic stents. Arch Surg 1998;133:935-8]. The symptoms of IVC obstruction include progressive ascites, scrotal edema and lower body edema. These constellations of symptoms are described as IVC syndrome and are devastating to a patient with end-stage cancer. We describe a palliative therapy utilizing Luminexx nitinol self-expanding stents to treat intracaval hepatoma thrombus obstructing the IVC. The procedure is rapidly ...

UK PubMed Central (United Kingdom)

BackgroundATRX is a tightly-regulated multifunctional protein with crucial roles in mammalian development. Mutations in the ATRX gene cause ATR-X syndrome, an X-linked...Full Text Available

UK PubMed Central (United Kingdom)

The most common cutaneous T-cell lymphomas (CTCLs) – mycosis fungoides (MF) and Sézary Syndrome – are characterised by the presence of clonally expanded, skin-homing helper-memory...Full Text Available

UK PubMed Central (United Kingdom)

AimsTo evaluate the associations of myocardial infarction (MI) and major bleeding with 1-year mortality. Both MI and major bleeding predict 1-year mortality in patients presenting...Full Text Available

International Nuclear Information System (INIS)

Patients with heterotaxy syndrome often have complex cardiac and extracardiac anomalies requiring further detailed diagnostic evaluation. They often present severe cardiac failure early in life. Newer radiological modalities in the form of spiral computed tomography (CT) and three-dimensional reconstruction of spiral CT allow clear definition of the anatomy of these anomalies. A 59-year-old woman was diagnosed with polysplenia and multiple anomalies in an abdominal ultrasonography (US) during a control medical examination due to a trivial dietary mistake. She was then referred to our institution for further examination of these anomalies and an additional thoraco-abdominal computed tomography (CT) examination. The patient was totally asymptomatic at the time of admission. There was no significant past history and no abnormal laboratory data. We performed abdominal, pelvic and thoracic CT examinations using Somatom Siemens Emotion scanner. Non-enhanced sections were ...

Energy Technology Data Exchange (ETDEWEB)

This paper reports the results of an investigation into the vibration of functionally graded cylindrical shells with flowing fluid, embedded in an elastic medium, under mechanical and thermal loads. By considering rotary inertia, the first-order shear deformation theory (FSDT) and the fluid velocity potential, the dynamic equation of functionally graded cylindrical shells with flowing fluid is derived. Here, heat conduction equation along the thickness of the shell is applied to determine the temperature distribution and material properties are assumed to be graded distribution along the thickness direction according to a power-law in terms of the volume fractions of the constituents. The equations of eigenvalue problem are obtained by using a modal expansion method. In numerical examples, effects of material composition, thermal loading, static axial loading, flow velocity, medium stiffness and shell geometry parameters on the free vibration ...

Energy Technology Data Exchange (ETDEWEB)

The structure and vibrational properties of high voltage cathode materials, namely LiNi{sub 1-y}CO{sub y}VO{sub 4} solid solution with (0{<=}y{<=}1), have been studied using X-ray diffraction, Raman scattering and FTIR measurements. Rietveld refinements show that LiNi{sub 1-y}Co{sub y}VO{sub 4} vanadates belong to the inverse spinel structure with Fd3m(O{sup 7}{sub h}) space group. Analysis of Raman spectra has been carried out in the molecular approximation using a local environment model including VO{sub 4} tetrahedra, (Ni, Co)O{sub 6} and LiO{sub 6} octahedra as vibrational local units. (orig.)

Energy Technology Data Exchange (ETDEWEB)

The Schroedinger equation for nuclear quadruple surface vibrations is linearized with the consequence that a new spin degree of freedom appears in the wave function of the linearized equation. This spin is called collective spin and has a value of 3/2. The linearized Schroedinger equation for quadrupole vibrations is used for the description of certain collective aspects of even-odd {sup 187,189,191}Ir nuclei which have a spin 3/2 in their ground state. As a potential we use the {gamma}-soft collective potential of the neighboring even-even nuclei, which is inserted into the linearized Schroedinger equation via a scalar coupling. This leads to a collective spin-dependent fine structure splitting of the energy levels governed by a collective SO(5) spin-orbit coupling and a correction to the kinetic energy. Further, we consider explicitly spin-dependent potentials which effectively describe the interaction of the valence nucleon with the core of ...

International Nuclear Information System (INIS)

Isomers have been populated in "2"4"6Cm and "2"5"2No with quantum numbers K"#pi#=8"-, which decay through K"#pi#=2"- rotational bands built on octupole vibrational states. For N=150 isotones with (even) atomic number Z=94-102, the K"#pi#=8"- and 2"- states have remarkably stable energies, indicating neutron excitations. An exception is a singular minimum in the 2"- energy at Z=98, due to the additional role of proton configurations. The nearly constant energies, in isotones spanning an 18% increase in Coulomb energy near the Coulomb limit, provide a test for theory. The two-quasiparticle K"#pi#=8"- energies are described with single-particle energies given by the Woods-Saxon potential and the K"#pi#=2"- vibrational energies by quasiparticle random-phase approximation calculations. Ramifications for self-consistent mean-field theory are discussed.

International Nuclear Information System (INIS)

Conventional methods for reducing vibration in engineering designs (i.e. by stiffening or detuning) may be undesirable or inadequate in conditions where size or weight must be minimized or where complex vibration spectra exist. Alloys which combine high damping capacity with good mechanical properties can provide attractive technical and economic solutions to problems involving seismic, shock and vibration isolation. To meet these trends, we have developed a new high damping Fe-17%Mn alloy. Also, the alloy has advantages of good mechanical properties and is more economical than any other known damping alloys (a quarter the cost of non-ferrous damping alloy). Thus, the high damping Fe-17%Mn alloy can be widely applied to household appliances, automobiles, industrial facilities and power plant components with its excellent damping capacity (SDC, 30%) and mechanical property (T.S. 700 MPa). It is the purpose of this paper to ...

British Library Electronic Table of Contents (United Kingdom)

In this study, wood samples were exposed to light irradiations (direct sunlight, xenon lamp, mercury vapour lamp) and thermal treatments were carried out in dry- and in humid conditions at 90degreeC. One part of the samples was covered by an aluminium plate during light irradiation. The samples under the aluminium plate also suffered considerable chemical changes, monitored by infrared technique and colour measurement. The sunlight produced greater colour change under the aluminium plate than the artificial light sources. During light irradiation, the carbonyl band having two maximum at 1700 and 1746cm-1 increased and the peak of the aromatic skeletal vibration arising from lignin (1510cm-1) decreased together with the guaiacyl vibrations at 1275cm-1. There was absorption decrease at 1174c...

International Nuclear Information System (INIS)

The effects of vibration isolation of the new type of mechanical damper applied to a single-degree-of-freedom system and a simple beam are discussed numerically and experimentally. The damper is composed of a ball screw, a flywheel and centrifugal brakes, and possesses nonlinear characteristics. The Continuous System Simulation Language is used for the digital simulations of the nonlinear vibration systems. The results may be summarized as follows: (1) The damper is effective for suppressing the amplitude of the single-degree-of-freedom system as well as of the beam at the point of attachment of the damper, at the resonances. (2) The damper approaches a snubber for smaller values of lead L of the ball screw (or larger values of moment of inertia J of the flywheel), and acts like a damper whose damping force is proportional to the square of the velocity for larger values of L (or smaller values of J). (author).

International Nuclear Information System (INIS)

The linearized collective Schroedinger equation for nuclear quadrupole surface vibrations incorporates a new spin degree of freeedom with a spin value of 3/2. We use this equation to describe the low energy spectrum of certain even-odd Ir nuclei which have a spin 3/2 in their ground state. For that purpose we explicitly introduce collective spin-dependent potentials which simulate the interaction of the valence nucleon with the core. The linearized Schroedinger equation is transformed into an effective Schroedinger equation with collective spin-dependent potentials. Already collective spin-orbit couplings of SO(3) and SO(5) type are sufficient to reproduce the lowest excited states of even-odd Ir nuclei. (orig.).

CERN Document Server

An effect of laser-cooling of water was observed for the first time with a temperature decrease dT = -2.2 K after irradiation of liquid water surface by a powerful Ar-Xe pulse laser with a pulse energy of about 1 J and wavelength L = 1.73, 2.63 and 2.65 um. The discovered effect can apparently be ascribed to the optical excitation of vibrational states of H2O molecules followed by an endothermic consolidation of chemically active excited molecules into a quasi-stable cluster-like structure. The measured time dependences of the cooling effect show that a typical life time of the new state of water amounts to hours. It has also been shown that the life time of the excited vibrational molecular states due to a radiation trapping effect can be estimated to at least hundreds of seconds.

Energy Technology Data Exchange (ETDEWEB)

This paper reports that fluidelastic instability is the most important vibration excitation mechanism for heat exchanger tube bundles subjected to cross-flow. Most of the available data on this topic have been reviewed from the perspective of the designer. Uniform definitions of critical flow velocity for instability, damping, natural frequency and hydrodynamic mass were used. Nearly 300 data points were assembled. The authors found that only data from experiments where all tubes are free to vibrate are valid form a design point of view. In liquids, fluid damping is important and should be considered in the formulation of fluidelastic instability. From a practical design point of view, we conclude that fluidelastic instability may be expressed simply in term of dimensionless flow velocity and dimensionless mass-damping. There is no advantage in considering more sophisticated models at this time. Practical design guidelines are discussed.

International Nuclear Information System (INIS)

The research and development of a new type of high damping rubber damper for high rise buildings/structures to mitigate earthquake or wind-induced structural response is described in this paper. The static tests were carried out to investigate restoring force characteristics using scale model of high damping rubber damper. The repetitive tests and the temperature dependency tests were carried out to investigate variance of performance of energy absorption. It is confirmed that the damping force characteristics of the damper can be considered as that of linear viscous damping and the damper sufficiently dissipates energy for vibrations of mm order to that of generating 200% shear strain. The design methods, based on assuming linear viscous damping for the damper, has been developed. The designed values such as stiffness and damping coefficient of the damper agree well with the experimental results. (author)

British Library Electronic Table of Contents (United Kingdom)

In this study, a new type of thin, compact, and light weighed diaphragm micro-pump has been successfully developed to actuate liquid by the vibration of a diaphragm. The micro-diaphragm pump with two valves is fabricated in an aluminum case by using highly accurate CNC machine, and the cross-section dimension is 28?mm??5?mm. Both valves and diaphragm are manufactured from PDMS. The amplitude of vibration by a piezoelectric device produces an oscillating flow and alters the chamber volume by the curvature change of a diaphragm. Several experimental set-ups for performance tests in a single micro-diaphragm pump, isothermal flow open system, and a closed liquid cooling system are designed and implemented. The performance of a one-side actuating micro-diaphragm pump is affected by the design ...

British Library Electronic Table of Contents (United Kingdom)

Forced harmonic vibration of a non-uniform elastic beam with attached dynamic vibration absorbers (DVA) is studied. Analytical approximation of the solution is obtained by the functional perturbation method (FPM). The problem has application to cutting tools operations where the resistance of the tool holder against regenerative chatter can be enhanced by optimizing the real part of the frequency response function (FRF). A test case of a beam with step-like heterogeneity and single DVA at the tip shows that the FPM solution is very accurate for up to ?40 percent deviation in both stiffness and mass density. Using the analytical results and Sims approach, optimal DVA tuning is found for each set of beam heterogeneity parameters by solving a set of nonlinear algebraic equations numer...

British Library Electronic Table of Contents (United Kingdom)

A joint experimental and theoretical analyses based on the grounds of DFT anharmonic potential and the use of a variational method allow us to revisit and assign the gas phase spectra of vinylarsine in the mid-IR area until 6300cm-1. Several weak and very weak bands corresponding to overtones and combinations are newly observed and assigned in complement to the fundamental bands.

British Library Electronic Table of Contents (United Kingdom)

The work is devoted to a microscopic analysis of the reactive capacity of chitin. An algorithm for modeling the deacetylation reaction in a monomeric unit of chitin is described. The reaction coordinate and the potential energy surface topography are determined taking into account the electron-vibrational interaction and low-symmetry perturbations within Jahn-Teller theory. Based on this algorithm, the topological modeling of the deacetylation process is performed for the first time and a mechanism of the biological activity of chitosan is proposed.

Science.gov (United States)

Sandwich panels have a very high stiffness to weight ratio, which makes them particularly useful in the aerospace industry where carbon fibre reinforced plastics and lightweight honeycomb cores are being used in the construction of floor panels, fairings and intake barrel panels. In the latter case, the geometry of the panels can be considered doubly curved. This paper presents an introduction to an ongoing study investigating the dynamic response prediction of acoustically excited composite sandwich panels which have double curvature. The final objective is to assess and hopefully produce an up to date set of acoustic fatigue design guidelines for this type of structure. The free vibration of doubly curved composite honeycomb sandwich panels is investigated here, both experimentally and theoretically, the latter using a commerically available finite element package. The design and manufacture of three test panels is covered before presenting experimental results ...

Science.gov (United States)

Silicone-rubber washers function as damping and articulating elements in cast-aluminum spacers that separate bundle subconductors in each phase of extra-high-voltage transmission lines. Spacer/dampers are located every 3 ft. along transmission lines on Canada's first operational 500 and 735 kV system.

Science.gov (United States)

Attention is given to recent research on gear fault diagnostic techniques. A mathematic model for vibration signals of defective gears is presented. Novel methods of gear fault diagnosis, such as zoom complex envelope analysis, wideband demodulation techniques, bispectrum analysis, correlation spectrum analysis, and maximum entropy spectrum analysis, are demonstrated. The wide-band demodulation technique is found to exhibit a high SNR. Bispectrum and correlation spectrum are excellent for some mechanical fault forms.

UK PubMed Central (United Kingdom)

In this work we study the temperature dependence of the Soret band lineshape of the carbonmonoxy derivatives of sperm whale myoglobin, human hemoglobin, and its isolated alpha and beta subunits. To...Full Text Available

International Nuclear Information System (INIS)

It is maintained that special features of FFTF make it an ideal system to test sodium boiling detection techniques by acoustic/neutronic methods and to test the response of acoustic/neutronic sensors to vibrations. It is shown that accumulated research results indicate that such tests in FFTF are feasible, predictable, promising and safe. (author).

International Nuclear Information System (INIS)

The essential difference as well as the apparent identity between the triaxial-rotor model and the gamma-vibrational model have been discussed. From the gamma decay mode, the [19/2"-]_1 states of the j = 11/2"- family in "1"8"7Ir and "1"8"9Ir have been identified as the K = j + 4 states, the presence of which contradicts the particle plus triaxial-rotor model. (author).

International Nuclear Information System (INIS)

Nanocrystalline materials can exhibit properties which are considerably different from their coarse-grained counterparts, making them unique for basic or applied research and also very promising for potential applications. The topics which are addressed in the present paper are magnetic properties and magnetic correlations on the nanometer scale, mechanical properties, in particular the influence of grain boundaries on the elastic and plastic behaviour, and vibration models of grain boundary atoms in nanostructured materials. (author)

Energy Technology Data Exchange (ETDEWEB)

This report continues the studies of simplified methods, of magnetic diagnostics in application to TCA/BR tokamak. Here we study the accuracy of known formula for {beta}{sub 1} + l{sub 1}/2 determination from the poloidal magnetic field asymmetry. Errors of the diamagnetic measurements due to vibrations of the vacuum vessel are also considered. (author). 3 refs., 1 fig., 1 tab.

International Nuclear Information System (INIS)

The governor model is extended to include the asymmetric shape of nuclei which allows a simultaneous analysis of the data for both the ground state and the #gamma#-vibrational bands in deformed even-even nuclei. The rotationally invariant core is assumed to be a spheroid with an axis of symmetry parallel to the axis of rotation. The calculations are carried out under the assumption of no stretching. The static #gamma#-deformation results are compared with the VMI(ARM) and Krutov values, and the calculated energies are in good agreement with the experimental data.

Science.gov (United States)

An analysis of the diagnosis of loading and service dependability of a rail-mounted excavator used in surface lignite mining is described. Wheel power vibrations in electric motor bearings and electric motor input bearings to the gearbox were measured in situ, in horizontal, vertical, and axial directions. The data were analyzed using a mathematical relationship. The results are presented in a loading diagram that shows the deterioration and the acceptable lower bound of machine conditions over time. Work is continuing. 5 refs., 1 fig.

Energy Technology Data Exchange (ETDEWEB)

Machine condition monitoring (MCM) has the capability to predict equipment maintenance needs which can reduce forced down-time and facilitate the avoidance of catastrophic failures and the consequential secondary damage. It can be used to allow confident deferral of routine maintenance, and improve equipment performance, availability, reliability and safety. In order to capitalize on the potential benefits of MCM directed toward power transformers two types of vibration tests were conducted on transformers owned and operated by Cargill Inc. and IES Utilities at the Bridgeport corn plant in Eddyville, Iowa. These tests involved collecting vibration signals from the transformer tank walls during transformer energization at no-load and during steady state operation at various loads. These vibration signals were then used to detect deterioration of internal mechanical integrity. Both types of tests conducted on the transformers ...

Science.gov (United States)

Pain is necessary for survival but chronic pain is disabling and causes significant health and economic problems. This study provides an understanding of the future for spinal cord stimulation. Stimulation by means of chronically implanted electrodes, was carried out in 200 patients with pain of varied benign organic etiology. In 177 of them, pain was confined to the failed back syndrome. Most patients were referred by a Pain Management Service. 226 epidural implants were used: 80 unipolar, 59 Resume, 12 bipolar, and 75 quadripolar. Patients were followed for periods of 6 months to 12 years, with a mean follow-up of 44 months. 84 patients (42%) were able to control their pain by stimulation alone, 22 patients (11%) needed occasional analgesic supplements along with their stimulation program. Pain secondary to failed back syndrome, multiple sclerosis, peripheral vascular disease, sympathetic dystrophy and diabetic neuropathy responded favorably. ...

Science.gov (United States)

We performed histological examination of 69 samples of Acropora sp. manifesting different types of tissue loss (Acropora White Syndrome-AWS) from Hawaii, Johnston Atoll and American Samoa between 2002 and 2006. Gross lesions of tissue loss were observed and classified as diffuse acute, diffuse subacute, and focal to multifocal acute to subacute. Corals with acute tissue loss manifested microscopic evidence of necrosis sometimes associated with ciliates, helminths, fungi, algae, sponges, or cyanobacteria whereas those with subacute tissue loss manifested mainly wound repair. Gross lesions of AWS have multiple different changes at the microscopic level some of which involve various microorganisms and metazoa. Elucidating this disease will require, among other things, monitoring lesions over time to determine the pathogenesis of AWS and the potential role of tissue-associated microorganisms in the genesis of tissue loss. Attempts to experimentally induce AWS should ...

Energy Technology Data Exchange (ETDEWEB)

Central nervous system (CNS) manifestations in acquired immunodeficiency syndrome (AIDS) patients are an early and common feature. The spectrum of AIDS-related CNS diseases are encephalitis caused by the human immunodeficiency virus(HIV) itself, opportunistic infection, infarct and malignancy. We experienced two cases of CNS involvement in AIDS and they were serologically diagnosed as HIV encephalitis and CNS toxoplasmosis, respectively. In the case of the HIV encephalitis patient, brain MRI showed a non-enhancing lesion with high signal intensity on T2WI and low signal on T1WI and there was no mass effect on the right frontal lobe, periventricular white matter, splenium of the corpus callosum or bilateral basal ganglia. In the other case of CNS toxoplasmosis, MR showed multiple nodular and rim enhanced mass lesions in the right basal ganglia, thalamus and periventricular white matter, which were of low signal intensity on T1WI and of high intensity on T2WI. We ...

Energy Technology Data Exchange (ETDEWEB)

The effectiveness of Noveko's antimicrobial filter was evaluated after 16 months of exposure to commercial swine production. The experiment involved the use of a scaled model of a commercial swine facility consisting of 2 small chambers connected by a duct containing the filters. A 5 kg naive pig was placed in the reception chamber for a period of 6 hours after aerosolization with porcine reproductive and respiratory syndrome virus (PRRSV). Blood samples from pigs were collected before and after aerosolization to test for the presence of PRRSV RNA. Only blood samples were tested for PRRSV antibodies by IDEXX 2XR ELISA. None of the 9 pigs tested were found to be infected. The study showed that the technology used to integrate the antimicrobial agent into the filter fibers allows the filter combination to withstand extreme weather and endure commercial swine production for at least 16 months, and can maintain its effectiveness to avoid airborne transmission ...

Science.gov (United States)

Stem cell research has important implications for medicine. The source of stem cells influences their therapeutic potential, with stem cells derived from early-stage embryos remaining the most versatile. Somatic cell nuclear transfer (SCNT), a source of embryonic stem cells, allows for understandings about disease development and, more importantly, the ability to yield embryonic stem cell lines that are genetically matched to the somatic cell donor. However, SCNT requires women to donate eggs, which involves injection of ovulation-inducing hormones and egg retrieval through laparoscopy or transvaginal needle aspiration. Risks from this procedure are fiercely debated, most notably risk of ovarian hyperstimulation syndrome (OHSS). This review examines risk of OHSS resulting from oocyte donation. We conclude that risk posed by OHSS in egg donation is not significant enough to warrant undue concern, and much of this can be eliminated when proper precautions are taken. ...

International Nuclear Information System (INIS)

Full text: Chemical-technology approaches allowing to intensification the prevention processes of gas hydrates formation at motion of gas-liquid stream of natural gas in system natural gas well - gas wire have been worked up. Technological regimes of treatment of gas stream have been determined. Linear correlation dependences inhibitor electrolytes contained hydrated ions with different ion radii and charges of subgroups of alkali elements with one - type electron configuration were obtained. Important physico-chemical parameters of electrolytes have been determined: activity; coefficients of activity, viscosity, diffusion; density; heat capacity; heat conductivity; surface tension and freezing-point. The features of continuous influence of inhibitory factors on process of gas flow at low temperatures and relatively high pressure differences ?P have been studied by using of technological installation modulating the system natural gas well - gas wire. The dependences of gas quantity ...

International Nuclear Information System (INIS)

Radioimmunoassay of serum myoglobin was done in 53 patients with polymyositis syndromes and other conditions. Serum myoglobin values in 33 healthy subjects ranged from 4 to 77 [mean 33.3 +/- 19.8 (SD)] ng/ml. Fifty percent of polymyositis patients had elevated serum myoglobin levels (greater than 80 ng/ml). Serum myoglobin values in polymyositis patients fluctuated more sensitively than CPK and GOT. Combined estimation of myoglobin and CPK offers advantages for the detection of muscle injury and the prediction of disease exacerbation.

Science.gov (United States)

Spinal cord stimulation (SCS) is frequently used for relief of chronic benign pain resistant to conservative therapies. Clinical practice suggests, at least in patients with failed back surgery syndrome (FBSS), the possibility that SCS significantly improves motor performances. We present here the case of a 41-years-old female patient with FBSS, who showed a clear improvement in muscle strength after SCS, persisting at 6-months follow-up. We speculate that the electrical stimulation of posterior columns could potentiate the caudal, segmental spinal reflexes resulting in a facilitation of motoneurons activation. PMID:16175150

International Nuclear Information System (INIS)

Computerized tomography of the adrenal glands was performed in 10 patients with Cushing's syndrome using a G.E. 8800 CT/T Body Scanner. The tomographic findings of unilateral adrenal masses in 4 patients were confirmed by surgery. In the remaining 6 patients, computerized tomography did not identify any masses, and both glands were well visualized and showed normal shape. In these patients, measurement of the adrenal glands revealed both normal (n=1) and enlarged glands (n=5). The findings of adrenalectomy (n=4) or transphenoidal surgery and follow-up (n=2) established the diagnosis of adrenal phyperplasia in all patients. (Author).

Energy Technology Data Exchange (ETDEWEB)

During the past 10 years, five infants with Kasabach-Merritt syndrome (K-M) receiving radiation therapy were reported. We investigated whether radiation therapy for K-M was useful and what the unfavorable factors of K-M were. During the past 10 years, we have treated five infants with K-M. The syndrome occurred at ages ranging from birth to 4 months. The incidence of female to male ratio was 3:2. Among 5 cases, the site of hemangioma was as follows; shoulder, anterior chest wall, lower abdominal wall, face and neck and inguinal site. All 5 cases received medication to control the coagulopathy including prednisone and blood transfusion at first. Because the platelet count and the bleeding tendency did not improve in any case, these cases received radiation therapy. Total dose ranged from 5 to 10 Gy and fraction-size ranged from 0.5 to 1.75 Gy. Irradiation session was 2 or 3 times per week. In 5 cases, 4 cases showed cure of bleeding tendency and ...

International Nuclear Information System (INIS)

Fuel assemblies in a reactor pressure vessel are disposed in a reactor core shroud. The own weight of the fuel assembly is supported by a reactor core support plate, and is supported, for the horizontal direction, by an upper lattice plate and the reactor core support plate. A support portion for the upper portion of the fuel assembly is disposed above the fuel assembly, and a support portion for the support portion described above is joined to a shroud head by welding. The support portion for the upper portion of the fuel assembly has a network-like portion which absorbs and disperses rising force which exerted on the fuel assembly when the fuel assembly is risen by seismic forces. The rising force exerted on the fuel assembly absorbed by the network-like portion is effectively transferred to the shroud head by the support portion. With such a constitution, rising of the fuel assembly can be prevented against the seismic vibrations having prominent vertical ...

Science.gov (United States)

The work reported in this paper addresses the problem of structure-borne sound transmission between vibrating sources and ribbed-plate receiver structures. Vibrating sources, such as pumps, motors, fans, etc., transmit vibro-acoustic power, causing noise complaints by occupants in cars, trains, aircraft, buildings and/or material fatigue and damage. The transmission process is complicated in that sources transmit power through several contacts and by up to six components of excitation at each contact. The structure-borne sound power is a function of source activity, source mobility and receiver mobility, and all three quantities must be known to some degree. For non-homogeneous receiver structures, such as thin-plate cavity constructions or lightweight framed constructions, the sheathing plates are typically fastened to the framing members using bolts, screws or spot-welded joints. Hence the resulting system is a point-connected ribbed plate ...

Science.gov (United States)

The fault signature can be revealed by vibration analysis in machine fault detection and diagnosis. Empirical mode decomposition (EMD) is a self-adaptive method that can decompose a vibration signal into informative intrinsic mode functions (IMFs). This paper addresses the improvement of the weakness of the traditional EMD algorithm and presents a new midpoint-based EMD method for effective fault signature analysis of a rotating machine. In the proposed method, geometrical midpoints of successive extrema are employed to estimate the local mean of an analyzed signal. Signal decomposition is then self-adaptively performed to achieve IMFs through removal of the midpoint-based local means. The representative IMF containing fault information is selected for identifying the fault signature. The effectiveness of the proposed method was verified by means of simulation and an application to gear fault diagnosis. Results indicated that the midpoint-based ...

International Nuclear Information System (INIS)

The objective of this work is the measurement of two-phase flow parameters to support development of constitutive relationships for the HANARO/MAPLE type finned fuel using Real-Time Neutron Radiography (RTNR). A single element finned Fuel Element Simulator was used with R134a Freon flow. To observe the effect of a spacer device on void distribution, single pin tests were performed with and without a spacer. By analyzing the RTNR images using image processing, the effects of the spacer on the time-averaged and instantaneous void fraction distributions were studied. For the experimental results without a spacer, the time-averaged local void distribution is radially asymmetric and the degree of void fluctuation increases with a decreasing frequency along the heated channel, where the observed asymmetry may be caused by flow induced vibration. For the experimental results with a spacer, the spacer clearly limits any significant vibration and the ...

Energy Technology Data Exchange (ETDEWEB)

In machine condition monitoring many fault-related vibration signals are highly non-stationary. Time-frequency representations comprise the natural signal-processing tool traditionally used for representing such non-stationary signals. The methods used in this analysis are based on the second order statistics of a signal. This paper discusses the use of higher order time frequency methods in the context of a condition monitoring application. The paper outlines the two classes of higher order representations: the L-Wigner distribution and the sliced Wigner higher order distribution. The use of higher order distributions introduces the possibility of non-oscillating cross-terms, a problem not encountered in conventional bilinear time-frequency methods. Techniques for reducing these cross-terms are presented. The paper compares the performance of bilinear and higher order time-frequency methods using synthetic data and vibration signals measured ...

International Nuclear Information System (INIS)

The measurement of two-phase flow parameters for development of constitutive relationships for the HANARO/MAPLE type finned fuel using Real-Time Neutron Radiography (RTNR) is discussed in this paper. A single element finned Fuel Element Simulator (FES) was used with Freon 134a as the working fluid. To observe the effect of a spacer device on void distribution, single pin tests were performed with and without a spacer present. By analyzing the RTNR images using image processing, the effects of the spacer on the time-averaged and instantaneous void fraction distribution were studied. For the experimental results without a spacer, the time-averaged local void distribution is radially asymmetric and the degree of void fluctuation increases with a decreasing frequency along the heated channel, where the observed asymmetry may be caused by flow induced vibration. For the experimental results with a spacer, the spacer clearly limits any significant ...

Energy Technology Data Exchange (ETDEWEB)

Youngkwang Unit 3,4 and Ulchin Unit 3 and 4 have had problem of the KSNP Steam Generator due to a severe fretting wear on the tube. In particular, the wears were localized and concentrated in the upper part of U-bend of the Central Cavity region. At the upper tube bundle Central Cavity, the fluid flow velocities and void fraction are very high, because the steam is made by high heat transfer at secondary region. Also, this region is affected easily by fretting wear due to it's unsupported span is longer than another regions. The fretting wear is assumed to be result of Flow-Induced Vibration (F. I. V), which can occur by many mechanisms. EFDP was added to UCN 5,6 for prevent fretting wear by the SEC LCC and DSHIC, a company of design and manufacture of the steam generator, respectively. In order to evaluate the efficacy of EFDP, ANSYS and ATHOS-3 Code were used. From sensitivity analysis and calculation results, Density and Velocity into the Central Cavity ...

Science.gov (United States)

The acid site distribution over large ZSM-5 crystals was analyzed using FTIR microscopy. Results of the analysis of the OH-stretching vibrations and of vibrations of pyridine adsorbed on Bronsted and Lewis acid sites were found to be in good agreement. The resolution which can be obtained using this novel technique is about 10-20 [mu]m. This limits the application to large crystals as analyzed in this study. Comparison of the results of IR microscopy with aluminum distributions obtained by electron microprobe analysis revealed that IR microscopy cannot resolve inhomogeneities on a scale smaller than the above-state limits. The results of both methods on a larger scale, however, are in very good agreement. Using a combination of both techniques, it is possible to obtain a clearer picture of the distribution of acid sites in large zeolite crystals, where electron microprobing gives the higher resolution, and IR microscopy allows the determination ...