WorldWideScience
1

UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications  

Science.gov (United States)

Cytosine methylation in DNA is a major epigenetic signal, and plays a central role in propagating chromatin status during cell division. However the mechanistic links between DNA methylation and histone methylation are poorly understood. A multi-domain protein UHRF1 (ubiquitin-like, containing PHD and RING finger domains 1) is required for DNA CpG maintenance methylation at replication forks, and mouse UHRF1-null cells show enhanced susceptibility to DNA replication arrest and DNA damaging agents. Recent data demonstrated that the SET and RING associated (SRA) domain of UHRF1 binds hemimethylated CpG and flips 5-methylcytosine out of the DNA helix, whereas its tandom tudor domain and PHD domain bind the tail of histone H3 in a highly methylation sensitive manner. We hypothesize that UHRF1 brings the two components ...

2009-01-01

2

ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome  

Energy Technology Data Exchange (ETDEWEB)

ATR-X (alpha-thalassemia/mental retardation, X-linked) syndrome is a human congenital disorder that causes severe intellectual disabilities. Mutations in the ATRX gene, which encodes an ATP-dependent chromatin-remodeler, are responsible for the syndrome. Approximately 50% of the missense mutations in affected persons are clustered in a cysteine-rich domain termed ADD (ATRX-DNMT3-DNMT3L, ADD{sub ATRX}), whose function has remained elusive. Here we identify ADD{sub ATRX} as a previously unknown histone H3-binding module, whose binding is promoted by lysine 9 trimethylation (H3K9me3) but inhibited by lysine 4 trimethylation (H3K4me3). The cocrystal structure of ADD{sub ATRX} bound to H3{sub 1-15}K9me3 peptide reveals an atypical composite H3K9me3-binding pocket, ...

2011-07-19

3

A Role for Set1/MLL-Related Components in Epigenetic Regulation of the Caenorhabditis elegans Germ Line  

UK PubMed Central (United Kingdom)

The methylation of lysine 4 of Histone H3 (H3K4me) is an important component of epigenetic regulation. H3K4 methylation is a consequence of transcriptional activity, but also has been shown to contribute...Full Text Available

2011-03-01

4

Identification of a Novel Inhibitor of Coactivator-associated Arginine Methyltransferase 1 (CARM1)-mediated Methylation of Histone H3 Arg-17*  

UK PubMed Central (United Kingdom)

Methylation of the arginine residues of histones by methyltransferases has important consequences for chromatin structure and gene regulation; however, the molecular mechanism(s) of methyltransferase...Full Text Available

2010-03-05

5

UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications  

UK PubMed Central (United Kingdom)

Cytosine methylation in DNA is a major epigenetic signal, and plays a central role in propagating chromatin status during cell division. However the mechanistic links between DNA methylation...Full Text Available

2009-01-01

6

The oxygenation of [3-methyl-3H]desacetoxycephalosporin C [7beta-(5-D-aminadipamido)-3-methylceph-3-em-4-carboxylic acid] to [3-hydroxymethyl-3H]desacetylcephalosporin C by 2-oxoglutarate-linked dioxygenases from Acremonium chrysogenum and Streptomyces clavuligerus.  

UK PubMed Central (United Kingdom)

Cell-free extracts of Acremonium chrysogenum and Streptomyces clavuligerus oxidize the 3-methyl group of desacetoxycephalosporin C to a 3-hydroxymethyl group. The enzyme responsible for this reaction...Full Text Available

1978-09-01

7

49 CFR 173.193 - Bromoacetone, methyl bromide, chloropicrin and methyl bromide or methyl chloride mixtures, etc.  

Science.gov (United States)

...false Bromoacetone, methyl bromide, chloropicrin and methyl bromide or methyl chloride...193 Bromoacetone, methyl bromide, chloropicrin and methyl bromide or methyl chloride...b) Bromoacetone, methyl bromide, chloropicrin and methyl bromide mixtures,...

2010-10-01

8

Local chromatin structure of heterochromatin regulates repeatedDNA stability, nucleolus structure, and genome integrity  

Energy Technology Data Exchange (ETDEWEB)

Heterochromatin constitutes a significant portion of the genome in higher eukaryotes; approximately 30% in Drosophila and human. Heterochromatin contains a high repeat DNA content and a low density of protein-encoding genes. In contrast, euchromatin is composed mostly of unique sequences and contains the majority of single-copy genes. Genetic and cytological studies demonstrated that heterochromatin exhibits regulatory roles in chromosome organization, centromere function and telomere protection. As an epigenetically regulated structure, heterochromatin formation is not defined by any DNA sequence consensus. Heterochromatin is characterized by its association with nucleosomes containing methylated-lysine 9 of histone H3 (H3K9me), heterochromatin protein 1 (HP1) that binds H3K9me, and Su(var)3-9, which methylates ...

2007-05-05

9

Methionine kinetics in adult men: effects of dietary betaine on L-[2H3-methyl-1-13C]methionine  

International Nuclear Information System (INIS)

The effects of a daily 3-g supplement of betaine on kinetic aspects of L-[2H3-methyl-1-13C]methionine (MET) metabolism in healthy young adult men were explored. Four groups of four subjects each were given a control diet, based on an L-amino acid mixture supplying 29.5 and 21.9 mg.kg-1.d-1 of L-methionine and L-cystine for 4 d before the tracer study, conducted on day 5 during the fed state. Two groups received the control diet and two groups received the betaine supplement. Tracer was given intravenously (iv) or orally. The transmethylation rate of MET (TM), homocysteine remethylation (RM), and oxidation of methionine were estimated from plasma methionine labeling and 13C enrichment of expired air. RM tended to increase (P = 0.14) but the TM and methionine oxidation were significantly (P less than 0.05) higher after betaine supplementation when estimated with the oral tracer. No differences were detected with the ...

10

Isotope effects on the metabolism and pulmonary toxicity of butylated hydroxytoluene in mice by deuteration of the 4-methyl group  

Energy Technology Data Exchange (ETDEWEB)

A comparative test in mice for pulmonary toxicity between butylated hydroxytoluene (2,6-di-tert.-butyl-4-methylphenol, BHT) and 2,6-di-tert.-butyl-4-(alpha, alpha, alpha-2H3)methylphenol (BHT-d3) showed a significantly lower toxic potency of the latter. The rate of in vitro BHT metabolism to 2,6-di-tert.-butyl-4-methylene-2,5-cyclohexadienone (BHT-QM) was slowed by deuterating BHT in the 4-methyl group. On the other hand, the rate of in vitro metabolism to 2,6-di-tert.-butyl-4-hydroxy-4-methyl-2,5-cyclohexadienone (BHT-OH) was increased with the deuteration. A similar isotope effect of the deuterium substitution on the in vivo metabolic rates of BHT was observed. These observations support the concept that the lung damage caused by BHT is mediated by BHT-QM. The pulmonary toxicity of 2-tert.-butyl-4-ethylphenol (4-EP) and their deuterated analogs was also compared. 2-tert.-Butyl-4-(1,1-2H2)ethylphenol ...

1983-06-30

11

Synthetic enantiopure aziridinomitosenes: preparation, reactivity, and DNA alkylation studies.  

Science.gov (United States)

An enantiocontrolled route to aziridinomitosenes had been developed from l-serine methyl ester hydrochloride. The tetracyclic target ring system was assembled by an internal azomethine ylide cycloaddition reaction based on silver ion-assisted intramolecular oxazole alkylation and cyanide-induced ylide generation via a labile oxazoline intermediate (62 to 66). Other key steps include reductive detritylation of 26, methylation of the N-H aziridine 56, oxidation of the sensitive cyclohexenedione 68 to quinone 70, and carbamoylation using Fmoc-NCO. Although the aziridinomitosene tetracycle is sensitive, a range of protecting group manipulations and redox chemistry can be performed if suitable precautions are taken. A study of DNA alkylation by the first C-6,C-7-unsubstituted aziridinomitosene 11a has been carried out, and evidence for DNA cross-link formation involving nucleophilic addition to the quinone subunit is described. ...

2003-12-24

12

Methionine kinetics and balance at the 1985 FAO/WHO/UNU intake requirement in adult men studied with L-[2H3-methyl-1-13C]methionine as a tracer  

International Nuclear Information System (INIS)

The upper range of the requirement for methionine plus cystine in healthy adults was proposed in 1985 by FAO/WHO/UNU to be 13 mg.kg body wt-1.d-1. To explore the validity of this estimate, five healthy, young adult men were given for 7 d a diet based on an L-amino acid mixture supplying 13 mg methionine.kg-1.d-1 (87 mumol.kg-1.d-1) without cystine. Constant intravenous infusions of L-[2H3-methyl-1-13C]methionine were given on days 5 and 7 while subjects were in the fed and postabsorptive states, respectively. Estimates were made of methionine oxidation, and daily methionine balance was derived from the intake-oxidation data. For the five subjects, methionine balances were -0.9, +0.7, +3.5, -3.1, and -3.8 mg kg-1.d-1, or -6, +5, +23, -21, and -26 mumol.kg-1.d-1. These findings lead to the conclusion that the upper range of the requirement for methionine plus cystine probably exceeds 13 mg.kg-1.d-1 in healthy young adults. ...

13

Synthesis and crystal structure of a new open-framework iron phosphate (NH4)4Fe3(OH)2F2[H3(PO4)4]: Novel linear trimer of corner-sharing Fe(III) octahedra  

International Nuclear Information System (INIS)

A new iron phosphate (NH4)4Fe3(OH)2F2[H3(PO4)4] has been synthesized hydrothermally at HF concentrations from 0.5 to 1.2 mL. Single-crystal X-ray diffraction analysis reveals its three-dimensional open-framework structure (monoclinic, space group P21/n (No. 14), a=6.2614(13) A, b=9.844(2) A, c=14.271(3) A, ?=92.11(1)o, V=879.0(3) A3). This structure is built from isolated linear trimers of corner-sharing Fe(III) octahedra, which are linked by (PO4) groups to form ten-membered-ring channels along [1 0 0]. This isolated, linear trimer of corner-sharing Fe(III) octahedra, [(FeO4)3(OH)2F2], is new and adds to the diverse linkages of Fe polyhedra as secondary building units in iron phosphates. The trivalent iron at octahedral sites for the title compound has been confirmed by synchrotron Fe K-edge XANES spectra and magnetic measurements. Magnetic measurements also show that this compound exhibit a strong antiferromagnetic ...

2010-12-01

14

 

Wastenet

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16

Magnetization and magnetic susceptibilities of GdH_3, HoH_3, ErH_3 and YbH_3  

International Nuclear Information System (INIS)

The magnetic susceptibility of powdered samples of HoH_3, ErH_3, GdH_3 and YbH_3 have been measured in the temperature range from 4.2 to 1.2 K. Two broad, local maxima are observed in the variation of chi versus T for GdH_3, with maxima in (delta chi/delta T) versus T at 1.8 K and 3.3 K. The inverse susceptibilities for HoH_3 and ErH_3 both obey a Curie--Weiss law over a limited range (4.2 to 2.6 K and 4.2 to 2 K, respectively) with values for the Weiss constant of -4.25 K and -1.11 K, and effective moments of 8.6 and 7.7 Bohr magnetons, respectively. The susceptibility of YbH_3 is independent of temperature over the range investigated. High-field ...

1976-03-29

17

Dissociation dynamics of methylal  

Energy Technology Data Exchange (ETDEWEB)

The dissociation of methylal is investigated using mass spectrometry, combined with a pyrolytic radical source and femtosecond pump probe experiments. Based on preliminary results two reaction paths of methylal dissociation are proposed and discussed. (author) 4 fig., 3 refs.

1999-08-01

18

A new gene (alkB) of Escherichia coli that controls sensitivity to methyl methane sulfonate.  

UK PubMed Central (United Kingdom)

Seven mutants of Escherichia coli were isolated that are sensitive to methyl methane sulfonate but not to UV light. They exhibited decreased host cell reactivation capacity for methyl methane sulfonate-treated...Full Text Available

1983-03-01

19

Viscoelasticity of various gel films prepared from solvent-soluble constituents in coal; Sekitanchu no yobai kayoseibun kara sakuseishita shushu no gel maku no nendansei  

Energy Technology Data Exchange (ETDEWEB)

Viscoelasticity of gel films prepared from solvent-soluble constituents without ash of coal using the mixed solvent of carbon disulfide and N-methyl-2-pyrrolidinone (CS2-NMP) was measured to study the network structure of the constituents. In experiment, Upper Freeport coal and Zao Zhuang coal were used as specimens. Viscoelasticity of various gels with different weight fractions of solvent was measured by creep measurement under a fixed load and stress-strain analysis under variable loads. In the 2nd and 3rd creep measurements, although no large changes in elastic strain and viscoelastic strain were found, viscous strain gradually decreased with an increase in viscosity. In the case of small weight fraction of solvent, small viscous strain and viscoelastic strain were found, while slightly large elastic strain was found. It was thus suggested that this elastic strain is derived from not only physical cross-linked networks by coal-solvent ...

1996-10-28

20

Operation of a laboratory-scale tubular digester on pigery waste  

Energy Technology Data Exchange (ETDEWEB)

Three inclined tubular digesters of 13- to 15-litre volume were operated at temperatures between 20 and 30 degrees C with hydraulic retention times of 10-15 days on pig slurry of 10%, 5% and 2.5% Total Solids content. Tube inclination of 16-20 degrees gave no scumming problems. Solids were retained, giving improved gas yields when compared with literature values for conventional stirred digesters. Solids retention is affected by the size of the digester exit and appears to be greater with slurry of low solids content. There is a link between the movement of solids and gas along, and out of, the digester which can lead to unstable oscillating gas production. Tracer studies showed soluble components of the slurry mixed throughout the whole volume of the digester in 25% of the hydraulic retention time or less. Solids moved in well dispersed plug flow. Gas production (both intrinsic and after the addition of acetate) was most rapid in the central section of the ...

1986-01-01

21

Monovalent cation-induced structure of telomeric DNA: The G-quartet model  

Energy Technology Data Exchange (ETDEWEB)

We have investigated the structures formed by oligonucleotides composed of two or four repeats of the telomeric sequences from Oxytricha and Tetrahymena. The Oxytricha four-repeat molecule (d(T4G4)4 = Oxy-4) forms structures with increased electrophoretic mobility in nondenaturing gels containing Na+, K+, or Cs+, but not in gels containing Li+ or no added salt. Formation of the folded structure results in protection of a set of dG's from methylation by dimethyl sulfate. Efficient UV-induced cross-links are observed in Oxy-4 and the related sequence from Tetrahymena (d(T2G4)4 = Tet-4), and join thymidine residues in different repeats. Models proposed to account for these data involve G-quartets, hydrogen-bonded structures formed from four guanosine residues in a square-planar array. We propose that the G-quartet structure must be dealt with in vivo by the telomere replication machinery.

1989-12-01

22

Site-Specific Methylation of the Promoter Alters Deoxyribonucleic Acid-Protein Interactions and Prevents ...  

Science.gov (United States)

... and R. L. Momparler. DNA methylation of retinoic acid receptor beta in breast cancer and possible therapeutic role of ... ...

23

Methods in DNA methylation profiling  

UK PubMed Central (United Kingdom)

Metastable and somatically heritable patterns of DNA methylation provide an important level of genomic regulation. In this article, we review methods for analyzing these genome-wide epigenetic...Full Text Available

2009-12-01

24

Synthesis, characterization, and evaluation of a novel bifunctional chelating agent for the lead isotopes {sup 203}Pb and {sup 212}Pb  

Energy Technology Data Exchange (ETDEWEB)

Radioisotopes of Pb(II) have been of some interest in radioimmunotherapy and radioimmunoimaging (RII). However, the absence of a kinetically stable bifunctional chelating agent for Pb(II) has hampered its use for these applications. {sup 203}Pb (T{sub 1/2}=52.02 h) has application potential in RII, with a {gamma}-emission that is ideal for single photon emission computerized tomography, whereas {sup 212}Pb (T{sub 1/2}=10 h) is a source of highly cytotoxic {alpha}-particles via its decay to its {sup 212}Bi (T{sub 1/2}=60 min) daughter. The synthesis of the novel bifunctional chelating agent 2-(4-isothiocyanotobenzyl)-1,4,7,10-tetraaza-1,4,7,10-tetra-(2-carbamoyl methyl)-cyclododecane (4-NCS-Bz-TCMC) is reported herein. The Pb[TCMC]{sup 2+} complex was less labile to metal ion release than Pb[DOTA]{sup 2-} at pH 3.5 and below in isotopic exchange experiments. In addition to increased stability to Pb{sup 2+} ion release at low ...

2000-01-01

25

Synthesis, characterization, and evaluation of a novel bifunctional chelating agent for the lead isotopes "2"0"3Pb and "2"1"2Pb  

International Nuclear Information System (INIS)

Radioisotopes of Pb(II) have been of some interest in radioimmunotherapy and radioimmunoimaging (RII). However, the absence of a kinetically stable bifunctional chelating agent for Pb(II) has hampered its use for these applications. "2"0"3Pb (T_1_/_2=52.02 h) has application potential in RII, with a #gamma#-emission that is ideal for single photon emission computerized tomography, whereas "2"1"2Pb (T_1_/_2=10 h) is a source of highly cytotoxic #alpha#-particles via its decay to its "2"1"2Bi (T_1_/_2=60 min) daughter. The synthesis of the novel bifunctional chelating agent 2-(4-isothiocyanotobenzyl)-1,4,7,10-tetraaza-1,4,7,10-tetra-(2-carbamoyl methyl)-cyclododecane (4-NCS-Bz-TCMC) is reported herein. The Pb[TCMC]"2"+ complex was less labile to metal ion release than Pb[DOTA]"2"- at pH 3.5 and below in isotopic exchange experiments. In addition to increased stability to Pb"2"+ ion release at low pH, the bifunctional TCMC ...

2000-01-01

26

Free radicals in lysozyme reacted with peroxidizing methyl linoleate  

International Nuclear Information System (INIS)

... electron spin resonance gamma radiation lipids lyophilization lysozyme radicals

27

Polyadenylated H3 histone transcripts and H3 histone variants in alfalfa.  

UK PubMed Central (United Kingdom)

Histone H3 mRNAs were found in polyA(+) fractions of total RNA prepared from alfalfa plants, calli and somatic embryos. The sequence analysis of cDNAs revealed the presence of a polyA tail on independent...Full Text Available

1989-04-25

29

ras gene alterations in invasive and non-invasive rat bladder carcinomas induced by N-methyl-N-nitrosourea.  

UK PubMed Central (United Kingdom)

We have established a reliable method to induce invasive and non-invasive carcinomas in the heterotopically transplanted urinary bladder of rats by repeated injection of N-methyl-N-nitrosourea (MNU),...Full Text Available

1991-07-01

30

The fission yeast gene pmt1+ encodes a DNA methyltransferase homologue.  

UK PubMed Central (United Kingdom)

DNA methylation of cytosine residues is a widespread phenomenon and has been implicated in a number of biological processes in both prokaryotes and eukaryotes. This methylation occurs at the 5-position...Full Text Available

1995-01-25

31

Scintillation proximity assay for measurement of RNA methylation  

UK PubMed Central (United Kingdom)

Methylation of RNA by methyltransferases is a phylogenetically ubiquitous post-transcriptional modification that occurs most extensively in transfer RNA (tRNA) and ribosomal RNA (rRNA). Biochemical...Full Text Available

2009-03-01

32

Practical, Stereoselective Synthesis of Cecropia Juvenile Hormone  

UK PubMed Central (United Kingdom)

The high-yield, stereoselective conversion of geraniol (3,7-dimethyl-trans-2,6-octadien-1-ol) to the insect juvenile hormone, methyl 12,14-dihomojuvenate (methyl cis-10-epoxy-3,11-dimethyl-7-ethyl-trans,...Full Text Available

1971-06-01

33

Methanogen Diversity Evidenced by Molecular Characterization of Methyl Coenzyme M Reductase A (mcrA) Genes in Hydrothermal Sediments of the Guaymas Basin  

UK PubMed Central (United Kingdom)

The methanogenic community in hydrothermally active sediments of Guaymas Basin (Gulf of California, Mexico) was analyzed by PCR amplification, cloning, and sequencing of methyl coenzyme M reductase...Full Text Available

2005-08-01

34

Induction of bladder cancer in rats by fractionated intravesicular doses of N-methyl-N-nitrosourea.  

UK PubMed Central (United Kingdom)

Experiments were conducted to determine the dose response of rat bladder urothelium to a range of different single and fractionated intravesicular doses of the carcinogen, N-methyl-N-nitrosourea (MNU)....Full Text Available

1982-03-01

35

Identification and Functional Relevance of de novo DNA Methylation in Cancerous B-Cell Populations  

UK PubMed Central (United Kingdom)

Epigenetic remodeling is a hallmark of cancer, with the frequent acquisition of de novo DNA methylation in CpG islands. However, the functional relevance of de novo...Full Text Available

2010-03-01

36

An Arabidopsis thaliana methyltransferase capable of methylating farnesoic acid?  

UK PubMed Central (United Kingdom)

We previously reported the identification of a new family of plant methyltransferases (MTs), named the SABATH family, that use S-adenosyl-l-methionine (SAM) to methylate...Full Text Available

2006-04-15

37

Intermediates to ethylene glycol: carbonylation of formaldehyde catalyzed by Nafion solid perfluorosulfonic acid resin  

Energy Technology Data Exchange (ETDEWEB)

Details of a series of reactions for the production of ethylene glycol using a catalyst of Nafion solid perfluorosulfonic acid resin was detailed. The reactions included the carbonylation of formaldehyde and esterification and then hydrogenation of the product of the carbonylation, glycolic acid. Other preparations included in the work included methyl glycolate, acetylglycolic acid, methyl acetylglycolate, and methyl methoxyacetate.

1983-01-01

38

Gene expression profiles deciphering rice phenotypic variation between Nipponbare (Japonica) and 93-11 (Indica) during oxidative stress.  

Science.gov (United States)

Rice is a very important food staple that feeds more than half the world's population. Two major Asian cultivated rice (Oryza sativa L.) subspecies, japonica and indica, show significant phenotypic variation in their stress responses. However, the molecular mechanisms underlying this phenotypic variation are still largely unknown. A common link among different stresses is that they produce an oxidative burst and result in an increase of reactive oxygen species (ROS). In this study, methyl viologen (MV) as a ROS agent was applied to investigate the rice oxidative stress response. We observed that 93-11 (indica) seedlings exhibited leaf senescence with severe lesions under MV treatment compared to Nipponbare (japonica). Whole-genome microarray experiments were conducted, and 1,062 probe sets were identified with gene expression level polymorphisms between the two rice cultivars in addition to differential expression under MV treatment, which were ...

2010-01-08

39

Hypomethylation and induction of retinoic acid receptor beta 2 by concurrent action of adenosine analogues and natural compounds in breast cancer cells  

British Library Electronic Table of Contents (United Kingdom)

DNA methylation is considered as a potential cause of aberrations in regulation of gene expression during carcinogenesis. Therefore, changes in DNA methylation patterns may be targets for chemoprevention. In the present study, we investigated effects of all-trans retinoic acid (ATRA), vitamin D3, and resveratrol alone and in combination with adenosine analogues: 2-chloro-2'-deoxyadenosine (2CdA) and 9-beta-d-arabinosyl-2-fluoroadenine (F-ara-A), on methylation and expression of retinoic acid receptor beta 2 (RARbeta2) in MCF-7 and MDA-MB-231 breast cancer cell lines. Alterations in methylation and expression levels after treatment of cells with the tested compounds were evaluated by methylation-sensitive restriction analysis (MSRA) and real-time PCR, respectively. RARbeta2 promoter in the ...

2010-01-01

40

Headspace gas chromatographic method for determination of methyl bromide in food ingredients  

Energy Technology Data Exchange (ETDEWEB)

A headspace gas chromatographic (GC) method, which can be automated, has been developed for determination of methyl bromide. This method has been applied to wheat, flour, cocoa, and peanuts. Samples to be analyzed are placed in headspace sample vials, water is added, and the vials are sealed with Teflon-lined septa. After an appropriate equilibration time at 32 degrees C, the samples are analyzed within 10 h. A sample of the headspace is withdrawn and analyzed on a gas chromatograph equipped with an electron capture detector (ECD). Methyl bromide levels were quantitated by comparison of peak area with a standard. The standard was generated by adding a known amount of methyl bromide to a portion of the matrix being analyzed and which was known to be methyl bromide free. The detection limit of the method was 0.4 ppb. The coefficient of variation (CV) was 6.5% for wheat, 8.3% for flour, 3.3% for cocoa, and ...

1985-11-01

41

FALP studies of dissociative recombination: the intriguing case of the (H_3"+ + e) reaction  

International Nuclear Information System (INIS)

The primary purpose of this short paper is to present a brief report on what we believe is state-of-the-art regarding the measurements of the dissociative recombination coefficient for the important interstellar ion H_3"+ at and near to thermal energies. However, theory has consistently indicated that dissociative recombination of H_3"+ should be inefficient at low energies. We do not try to present a detailed historical development of this topic here, but we rather refer the reader to our very recent papers and those of others. (author).

1994-03-20

42

NATIONALAIIVISBRY COMMITTEE Ffltt AERONAUTICS - NASA Technical ...  

Science.gov (United States)

Watkins,. Charles. E. : Effect of Aspect. Ratio on the Air ...... Grover,. H. 3. ; Bishop,. S. M. ; and. Jackson,. L. R. : Fatigue. Strengths of Aircraft ...

44

Antigenic drift in influenza virus H3 hemagglutinin from 1968 to 1980: multiple evolutionary pathways and sequential amino acid changes at key antigenic sites.  

UK PubMed Central (United Kingdom)

Surveys of the antigenic properties of a wide range of variants of the H3N2 (Hong Kong) influenza virus subtype have revealed complex patterns of variants cocirculating during each of the main epidemic...Full Text Available

1983-10-01

45

An improved synthesis of [5'-"3H]-3'-azido-3'-deoxythymidine, tritiated Zidovudine  

International Nuclear Information System (INIS)

[5'-"3H]-3'-Azido-3'-deoxythymidine (3) was prepared at a specific activity of 14.0 Ci/mmol by a two-step synthetic sequence involving controlled oxidation of the unlabelled compound (1) to the 5'-aldehyde (2) followed by reduction with ["3H]-NaBH_4. Purification was performed by preparative TLC. The radiochemical purity was 99.2%. (author).

46

6-Methyl-1,2,4-benzenetriol, a new intermediate in penicillic acid biosynthesis in Penicillium cyclopium  

International Nuclear Information System (INIS)

Penicillic acid-negative mutants were obtained from a color mutant derived from Penicillium cyclopium NRRL 1888 through N-methyl-N'-nitro-N-nitrosoguanidine treatment. One mutant (SK2N6) accumulated 6-methyl-1,2,4-benzenetriol, which was not previously known to be a metabolite of P. cyclopium, in addition to orsellinic acid and orcinol. The radioactivity of [1-"1"4C]acetic acid was rapidly incorporated into 6-methyl-1,2,4-benzenetriol in a culture of P. cyclopium SK2N6. Moreover, the radioactivity of ["1"4C]6-methyl-1,2,4-benzenetriol was efficiently incorporated into penicillic acid in a culture of P. cyclopium NRRL 1888. These data indicate that 6-methyl-1,2,4-benzenetriol is a precursor for penicillic acid biosynthesis. The results on the addition of 1,4-dihydroxy-6-methoxy-2-methylbenzene, 6-methoxy-2-methylbenzoquinone (1,4), and 1-O-methylorcinol to a culture of P. cyclopium ...

47

NTC Information  

Science.gov (United States)

602-906-5555 Important Links Electronic Reading Room HazMat Mgrs Tools Satellite Network Security Procedures Staff Directory Links - Partners Restricted access BLM NTC INTRANET...

2011-10-15

48

Geothermal: Related Links  

Science.gov (United States)

GEOTHERMAL TECHNOLOGIES LEGACY COLLECTION - Related Links Geothermal Technologies Legacy Collection Help/FAQ | Site Map | Contact Us | Admin Log On Home/Basic Search About...

2011-08-19

49

Factors Linked to Bacterial Vaginosis in Nonpregnant Women  

UK PubMed Central (United Kingdom)

Objectives. The purposes of this study were to test the hypothesis that vaginal douching is linked to bacterial vaginosis in both symptomatic and asymptomatic women and to identify...Full Text Available

2001-10-01

50

Reaction pathways of the dissociation of methylal: A DFT study  

Energy Technology Data Exchange (ETDEWEB)

Schemata for modelling combustion processes do not yet include reaction rates for oxygenated fuels like methylal (DMM) which is considered as an additive or replacement for diesel due to its low sooting propensity. Density functional theory (DFT) studies of the possible reaction pathways for different dissociation steps of methylal are presented. Cleavage of a hydrogen bond to the methoxy group or the central carbon atom were simulated at the BLYP/6-311++G{sup **} level of theory. The results are compared to the experiment when dissociating and/or ionising DMM with femtosecond pulses. (author) 1 fig., 1 tab., 1 ref.

1999-08-01

51

Addition of methyl cellulose enema to double-contrast barium imaging of sigmoid diverticulosis  

Energy Technology Data Exchange (ETDEWEB)

Double-contrast barium enema has a reduced sensitivity in patients with severe sigmoid diverticulosis. Therefore a carboxy methyl cellulose enema was employed after the conventional double-contrast examination in 15 patients with sigmoid diverticulosis. A significant increase in lumen diameter and a superior removal of barium residue from the diverticulas facilitated the interpretation of the sigmoid loops. Conclusion: The addition of methyl cellulose enema to double-contrast barium imaging improves diagnostic imaging in diverticulosis by expanding the lumen and emptying the diverticulas. (orig.).

1997-01-01

52

The Combined Influence of Molecular Weight and Temperature on the ...  

Science.gov (United States)

[12] Kusy, R. P. and Turner, D. T.: Influence of molecular-weight ofpoly(methyl methacrylate)on fracture morphology in notched tension, Polymer. ...

53

Recycling of poly(methyl methacrylate) scrap in the styrene-methyl methacrylate copolymer cast sheet process  

British Library Electronic Table of Contents (United Kingdom)

Poly(methyl methacrylate), PMMA, scrap generated during the casting process for PMMA cast sheet is an industrial waste stream, which has a high impact on the PMMA production cost and environment. This paper presents an alternative way to reduce the processing cost of PMMA cast sheet and decrease industrial waste by using styrene (S) as a co-monomer with methyl methacrylate (MMA) monomer, in conjunction with recycling of PMMA scrap in the S-MMA copolymer cast sheet process. The influence of factors, such as the concentrations of S and PMMA scrap, on the preparation of S-MMA copolymer cast sheet mixed with PMMA scrap was investigated. The characterization of basic copolymer composition, the physical, and the mechanical properties of the final products were examined. The results show that it ...

2009-01-01

54

2011 Critical Use Exemption Nominations from the Phaseout of...  

Science.gov (United States)

transmitted to the Ozone Secretariat of the United Nations Environment Programme (UNEP) its sixth nomination for a critical use exemption (CUE) from the phaseout of methyl...

2011-02-08

56

A study of the distribution of schistosomicidal drug H-3-7505 in mice  

Energy Technology Data Exchange (ETDEWEB)

The authors have studied the distribution of H-3 labelled schistosomicidal drug in mice by autoradiography. The H-3-labelled substances were found in liver and kidney and in successfully decreasing amounts in brain, lung, heart, fat, testis, pancreas and spleen. In various cells the silver granules were present mainly in the cytoplasms but a few in the nucleus. After administration of this labelled schistosomicidal drug, the mice were killed and studied in groups successively at 4, 8, 24 hrs. No difference in the distribution of silver granules were observed. This fact indicated that, this drug was rapidly absorbed and highly concentrated with a long duration of reservation in liver. All of these favours the schistosomicidal effect of the drug. As this drug was highly concentrated in the cytoplasm of liver cells, that might provide a pathophysiologic basis for the explanation of jaundice in the clinical ...

1985-05-01

57

Structural Chemistry of Human SET Domain Protein Methyltransferases  

Science.gov (United States)

There are about fifty SET domain protein methyltransferases (PMTs) in the human genome, that transfer a methyl group from S-adenosyl-L-methionine (SAM) to substrate lysines on histone tails or other peptides. A number of structures in complex with cofactor, substrate, or inhibitors revealed the mechanisms of substrate recognition, methylation state specificity, and chemical inhibition. Based on these structures, we review the structural chemistry of SET domain PMTs, and propose general concepts towards the development of selective inhibitors.

2011-08-22

58

Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics  

UK PubMed Central (United Kingdom)

ObjectivesThe aim of this study was to comprehensively evaluate the antibacterial activity and MurE inhibition of a set of N-methyl-2-alkenyl-4-quinolones found...Full Text Available

2011-08-01

59

Insect-Induced Conifer Defense. White Pine Weevil and Methyl Jasmonate Induce Traumatic Resinosis, de Novo Formed Volatile Emissions, and Accumulation of Terpenoid Synthase and Putative Octadecanoid Pathway Transcripts in Sitka Spruce1[w  

UK PubMed Central (United Kingdom)

Stem-boring insects and methyl jasmonate (MeJA) are thought to induce similar complex chemical and anatomical defenses in conifers. To compare insect- and MeJA-induced terpenoid responses, we analyzed...Full Text Available

2005-01-01

60

Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs  

UK PubMed Central (United Kingdom)

The N1-methyl-Adenosine (m1A58) modification at the conserved nucleotide 58 in the TΨC loop is present in most eukaryotic tRNAs. In yeast, m1A58 modification...Full Text Available

2010-07-01

61

Comultiplication in link Floer homology and transversely non-simple links  

CERN Document Server

For a word w in the braid group on n-strands, we denote by T_w the corresponding transverse braid in the rotational symmetric tight contact structure on S^3. We exhibit a map on link Floer homology which sends the transverse invariant associated to T_{ws_i} to that associated to T_w, where s_i is one of the standard generators of B_n. This gives rise to a "comultiplication" map on link Floer homology. We use this to generate infinitely many new examples of prime topological link types which are not transversely simple.

2009-01-01

62

Bisulfite genomic sequencing of DNA from dried blood spot microvolume samples.  

Science.gov (United States)

DNA methylation is an important event in epigenetic changes in cells, and a fundamental regulator of gene transcription. Bisulfite genomic sequencing is a powerful technique used in studies of DNA methylation. However, the established procedures often require relatively large amounts of DNA. In everyday practice, samples submitted for analysis might contain very small amounts of poor quality material, as is often the case with forensic stain samples. In this study, we assess a modified, more efficient method of bisulfite genomic sequencing. Genomic DNA extracted from 3-mm dried blood spots using QIAamp micro kit was treated with sodium bisulfite (using EpiTect kit). Subsequent methylation-specific PCR (MSP) followed by DNA sequencing displayed the differentially methylated region of imprinted gene SNRPN. Our results show that this new combination of efficient DNA extraction and bisulfite treatment ...

2011-07-01

63

Chronic Cocaine-Induced H3 Acetylation and Transcriptional Activation of CaMKII? in the Nucleus Accumbens Is Critical for Motivation for Drug Reinforcement  

UK PubMed Central (United Kingdom)

The regulation of gene expression in the brain reward regions is known to contribute to the pathogenesis and persistence of drug addiction. Increasing evidence suggests that the regulation of gene transcription...Full Text Available

2010-03-01

64

On-line partial discharge measurements and off-line dielectric spectroscopy measurements of six 115 kV XLPE cable systems  

Energy Technology Data Exchange (ETDEWEB)

This paper reported on a study in which partial discharge (PD) measurements were performed on 6 underground transmission cable circuits to determine the effectiveness of PD measurements on fluid fill cables. The cables were between 37 and 56 years old. PD activity was detected from the terminations of H11L and H3L Cable 2. However, for cables from H3L Basin TS to Mill Street junction, PD activity was detected originating from within the main cable insulation.

2009-07-01

65

The Gigabit Link Interface Board (GLIB), a flexible system for the evaluation and use of GBT-based optical links  

International Nuclear Information System (INIS)

The Gigabit Link Interface Board (GLIB) is an evaluation platform and an easy entry point for users of high speed optical links in high energy physics experiments. Its intended use ranges from optical link evaluation in the laboratory to control, triggering and data acquisition from remote modules in beam or irradiation tests. The GLIB is an FPGA-based Advanced Mezzanine Card (AMC) conceived to serve a small and simple system residing either inside a Micro Telecommunications Computing Architecture (?TCA) crate, or on a bench with a link to a PC. This paper presents the architecture of the GLIB, its features as well as examples of its use in different setups.

2010-11-01

66

Synthesis of C-11 iodoantipyrine for positron emission tomography  

Energy Technology Data Exchange (ETDEWEB)

We have developed a method for the synthesis of C-11 iodoantipyrine. Carbon-11-labeled methyl iodide, prepared from /sup 11/CO2, was used to methylate 3-methyl-1-phenyl-2-pyrazolin-5-one to form C-11 antipyrine. Following silica-gel column chromatography and iodination, radiochemical purity of the C-11 iodoantipyrine was more than 99.5%, with a 10% yield and a specific activity of 30 mCi/mumol. Preliminary animal studies showed complete cerebral extraction and local cerebral blood-flow values that were within 4.6% of those obtained using C-14 iodoantipyrine. The C-11 analog, with positron emission tomography, will facilitate local cerebral blood-flow studies in human subjects.

1981-06-01

67

Extraction of hafnium by 1-phenyl-3-methyl-4-benzoyl-5-pyralozone from aqueous-alcoholic solutions  

International Nuclear Information System (INIS)

Extraction of hafnium by 1-phenyl-3-methyl-4-benzoyl-5-pyrazolone (HL) in benzene, toluene, chloroform and tetrachloromethane from aqueous-alcoholic solutions of the formal acidity of 2M-HClO_4 was studied. Methyl, ethyl, n- and isopropyl, tert-butyl and allyl alcohol as well as ethylene glycol monomethyl ether and propylene glycol were used as organic components of the mixed aqueous-organic phase. Their presence in some cases resulted in a synergic increase in the distribution ratio of hafnium. The increase is interpreted using the results of a slope analysis and measurements of the alcohol distribution and the relative permittivity of the organic phase. It is suggested that HfL_4 molecules were solvated by alcohol molecules in the organic phase. At high alcohol concentration synergism changed into antagonism. This was caused by changes in the distribution of HL and its interaction with the alcohol in the organic phase. (author).

68

Combustion of jojoba methyl ester in an indirect injection diesel engine  

Energy Technology Data Exchange (ETDEWEB)

An experimental investigation has been carried out to examine for the first time the performance and combustion noise of an indirect injection diesel engine running with new fuel derived from pure jojoba oil, jojoba methyl ester, and its blends with gas oil. A Ricardo E6 compression swirl diesel engine was fully instrumented for the measurement of combustion pressure and its rise rate and other operating parameters. Test parameters included the percentage of jojoba methyl ester in the blend, engine speed, load, injection timing and engine compression ratio. Results showed that the new fuel derived from jojoba is generally comparable and a good replacement to gas oil in diesel engine at most engine operating conditions, in terms of performance parameters and combustion noise produced. (author)

2003-07-01

69

A study of methyl formate in astrochemical environments  

CERN Document Server

Several complex organic molecules are routinely detected in high abundances towards hot cores and hot corinos. For many of them, their paths of formation in space are uncertain, as gas phase reactions alone seem to be insufficient. In this paper, we investigate a possible solid-phase route of formation for methyl formate (HCOOCH3). We use a chemical model updated with recent results from an experiment where simulated grain surfaces were irradiated with 200 keV protons at 16 K, to simulate the effects of cosmic ray irradiation on grain surfaces. We find that this model may be sufficient to reproduce the observed methyl formate in dark clouds, but not that found in hot cores and corinos.

2011-01-01

70

A quantum theoretical study of reactions of methyldiazonium ion with DNA base pairs  

British Library Electronic Table of Contents (United Kingdom)

Methylation of the DNA bases in the Watson-Crick GC and AT base pairs by the methyldiazonium ion was investigated employing density functional and second order Moller-Plesset (MP2) perturbation theories. Methylation at the N3, N7 and O6 sites of guanine, N1, N3 and N7 sites of adenine, O2 and N3 sites of cytosine and the O2 and O4 sites of thymine were considered. The computed reactivities for methylation follow the order N7(guanine)>N3(adenine)>O6(guanine) which is in agreement with experiment. The base pairing in DNA is found to play a significant role with regard to reactivities of the different sites.

2011-01-01

71

X-linked nephrogenic diabetes insipidus mutations in North America and the Hopewell hypothesis.  

UK PubMed Central (United Kingdom)

In X-linked nephrogenic diabetes insipidus (NDI) the urine of male patients is not concentrated after the administration of the antidiuretic hormone arginine-vasopressin. This disease is due to mutations...Full Text Available

1993-09-01

72

Western Blot Analysis of Cereal Grain Prolamins Using an Antibody to Carboxyl-Linked Indoleacetic Acid  

UK PubMed Central (United Kingdom)

A monoclonal antibody raised against carboxyl-linked IAA was used in Western blot analysis of storage proteins from kernels of Avena sativa, Pennisetum americanum, Sorghum bicolor,...Full Text Available

1991-08-01

73

TELEMETRY LINK FOR Howard A. Baldwin and Robert W. - NASA ...  

Science.gov (United States)

Howard A. Baldwin and Robert W. Freyman. (NASA-CR-138152) TELEMERY LINK FOR AN. 574-2179 9 ..... Baldwin, H.A., "Long Range Radio Tracking of ...

74

Studies on Poly(propylene fumarate-co-caprolactone diol) Thermoset Composites towards the Development of Biodegradable Bone Fixation Devices  

UK PubMed Central (United Kingdom)

The effect of reinforcement in the cross-linked poly(propylene fumarate-co-caprolactone diol) thermoset composites based on Kevlar fibres and hydroxyapatite was studied. Cross-linked poly(propylene...Full Text Available

2009-01-01

75

Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia  

UK PubMed Central (United Kingdom)

Cilia are important cellular structures that have been implicated in a variety of signaling cascades. In this review, we discuss the current evidence for and against a link between cilia and both the...Full Text Available

2011-02-01

76

Self-Study Digital Library Courseware  

Science.gov (United States)

Tutorial on digital libraries. Site also contains links to other reference materials on digital libraries as well as links to courses on the subject. Keywords: Information Systems - Information Systems Applications, Information Storage and Retrieval, Database Management, multimedia

2001-12-01

77

RISK-XLR: A Microcomputer-Based Genetic Risk Program for X-Linked Recessive Traits  

UK PubMed Central (United Kingdom)

A computer program, RISK-XLR, which calculates genetic risk for carrier status of a Mendelian X-linked recessive condition has been written for the Macintosh series of microcomputers. The program,...Full Text Available

1987-11-04

78

Mechanism of cell death resulting from DNA interstrand cross-linking in mammalian cells  

UK PubMed Central (United Kingdom)

DNA interstrand cross-links (ICLs) are critical cytotoxic lesions produced by cancer chemotherapeutic agents such as the nitrogen mustards and platinum drugs; however, the exact mechanism of ICL-induced...Full Text Available

2011-08-01

79

Human Cloning  

Science.gov (United States)

... is known as "reproductive cloning." The Link to Stem Cell Research Stem cell research and research cloning are closely linked. Scientists in ... to arrive at a position on cloning and stem cell research. Many nations, including the UK, China, and South ...

80

Enzyme-Linked Immunosorbent Assay for Recombinant K39 Antigen in Diagnosis and Prognosis of Indian Visceral Leishmaniasis  

UK PubMed Central (United Kingdom)

The recombinant product (rK39) of the 39-amino-acid repeats encoded by a kinesin-like protein-encoding gene of Leishmania chagasi was evaluated by enzyme-linked immunosorbent assay...Full Text Available

2001-11-01

81

Effect of misonidazole pretreatment on nitrogen mustard-induced DNA cross-linking in mouse tissues in vivo.  

UK PubMed Central (United Kingdom)

In the present study we have used the alkaline elution technique to study the effect of misonidazole (MISO) on the initial amount of DNA cross-linking in various normal and neoplastic tissues of C3H...Full Text Available

1984-12-01

82

Determination of antibody response to influenza virus surface glycoproteins by kinetic enzyme-linked immunosorbent assay.  

UK PubMed Central (United Kingdom)

We modified an existing enzyme-linked immunosorbent assay (ELISA) to be able to use new spectrophotometers which can measure the rate of color development in microtiter wells. This new kinetic-based...Full Text Available

1988-10-01

83

Crassulacean Acid Metabolism and Epiphytism Linked to Adaptive Radiations in the Orchidaceae1[OA  

UK PubMed Central (United Kingdom)

Species of the large family Orchidaceae display a spectacular array of adaptations and rapid speciations that are linked to several innovative features, including specialized pollination syndromes,...Full Text Available

2009-04-01

84

Changes in Amide-Linked and Ester Indole-3-Acetic Acid in Cotton Fruiting Forms during Their Development  

UK PubMed Central (United Kingdom)

The concentration of free indoleacetic acid (IAA) is high in cotton (Gossypium hirsutum L.) fruiting forms before anthesis, but is low at and for a few days after anthesis. Amide-linked...Full Text Available

1989-03-01

85

BUBL LINK: Lung cancer  

Wastenet

...2 Resource type: documents Mesothelioma Information HON-code certified resource, covering the main aspects of asbestos exposure: diagnosis, diseases caused by asbestos, treatment options, prevention and legal options. Diagrams are included in articles, and links are provided to the references used. Also contains a listing of ...

86

Acne, dairy and cancer  

UK PubMed Central (United Kingdom)

A potent link to dairy seems to exist for three hormone-responsive glands. Acne, breast cancer and prostate cancer have all been linked epidemiologically to dairy intake. Although mechanisms postulated...Full Text Available

2009-01-01

87

metadata, images and captions. - The Gateway to Astronaut ...  

Science.gov (United States)

... the Zaire is not an efficient transportation link because of many rapids and falls to negotiate between Kinshasa and the port city of Matadi. ...

88

Wideband Modulation and Tuning of Semiconductor Lasers ...  

Science.gov (United States)

... Tunable semiconductor lasers are essential components for links employing optical frequency modulation (OFM) for enhanced dynamic range or ...

1996-07-01

89

The Sustainment Management Support Project  

Science.gov (United States)

... due to the evolving nature of the Strategy Maps and the changing priority roles, it was decided not to link the SMSP directly with any Strategic Plans. ...

2010-09-01

90

Orbiting transmitter and antenna for spaceborne communications at ELF/VLF to submerged submarines  

Science.gov (United States)

An orbital emplacement for the transmitter and the antenna of a communications link at ELF (30 to

1993-01-01

91

JFACC Afloat  

Science.gov (United States)

... 9 Integrated Battle Management System Data Link Architecture Common Mission Planring System MILSTAR and SATCOMs Common Aviation ...

1993-05-17

92

Congenital Adrenal Hyperplasia  

Medline Plus

... Resources and Links Kid's Newsletter Listserv's Grandparent's Newsletter Networking Personal Stories by Affected Kids & Adults (currently not ...

93

BUBL LINK Catalogue of Internet Resources  

Wastenet

...O | P | Q | R | S | T | U | V | W | X | Y | Z 230 Christianity: general resources ...com: Christianity: General Anno Domini: Jesus Through the Centuries Bible and Homosexuality Christian Theological Research Fellowship Papers Christianity Links and Resources Directory ...Good Digital Collections Lambert's Web Links MUNDUS New Testament Gateway Omnilist of Christian Starting Points Quartz Hill School of Theology Web Library Theology Online ...com: Christianity: General Offers original articles and features about Christianity in general plus annotated links to selected relevant Internet resources, compiled by ...

94

The effects of Al{sub 2}O{sub 3}-TiO{sub 2} coating in a diesel engine on performance and emission of corn oil methyl ester  

Energy Technology Data Exchange (ETDEWEB)

Today, as a result of increase in oil prices, limited fossil fuel resources, environmental consideration and global warming, the methyl ester fuels have been focused on alternative fuels. Methyl ester fuels can be used more efficiently in low heat rejection engines (LHR), in which the temperature of combustion chamber is increased by creating a thermal barrier. In this study, the piston, cylinder head, exhaust and inlet valves of a diesel engine were coated with the ceramic material Al{sub 2}O{sub 3}-TiO{sub 2} by the plasma spray method. Thus, a thermal barrier was provided for the parts of the combustion chamber with these coatings. The effects of corn oil methyl ester that produced by the transesterification method, and No. D2 fuels' performance and exhaust emissions' rate were studied by using equal in every respect coated and uncoated engines. Tests were performed on the uncoated engine, and then ...

2010-10-15

95

The biosynthesis of rubber from ?-hydroxy-?-methylglutaryl-coenzyme A in Hevea brasiliensis latex  

UK PubMed Central (United Kingdom)

1. β-Hydroxy-β-methyl[3-14C]glutaryl-CoA is efficiently incorporated into rubber on incubation with Hevea brasiliensis latex, and the incorporation is diminished...Full Text Available

1969-09-01

96

Synergism among BIOLF-62, phosphonoformate, and other antiherpetic compounds.  

UK PubMed Central (United Kingdom)

9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (BIOLF-62) is highly synergistic with either phosphonoformate or phosphonoacetate when used in combination against herpes simplex virus types 1 and...Full Text Available

1982-12-01

97

Surface structure recognized for covalent modification of the aspartate receptor in chemotaxis.  

UK PubMed Central (United Kingdom)

The aspartate receptor involved in chemotaxis is modified by methyl esterification at four distinct glutamate residues during the adaptive response of this receptor. To explain the high degree of specificity...Full Text Available

1986-09-01

98

Stable Isotope-Coded Quaternization for Comparative Quantification of Estrogen Metabolites by High-Performance Liquid Chromatography-Electrospray Ionization Mass Spectrometry  

UK PubMed Central (United Kingdom)

A fast and sensitive LC-ESI-MS method is described for the comparative quantification of 16 estrogen metabolites based on the derivatization of estrogens with a novel derivatizing reagent, N-methyl-nicotinic...Full Text Available

2008-07-15

99

Role of histone methylation and demethylation in adipogenesis and obesity  

UK PubMed Central (United Kingdom)

Adipocyte differentiation is a complex developmental process that involves the coordinated interplay of numerous transcription factors. PPARγ has emerged as a master regulator of adipogenesis...Full Text Available

2010-01-01

100

Removal of iodine species by concentrated nitric acid, (2)  

International Nuclear Information System (INIS)

One of the most effective removing processes of iodine species is what is called ''Iodox Process'', which contains oxidation and absorption of iodine species by highly concentrated nitric acid. The result of fundamental test with bubble column in this process had been reported. Present paper describes the fundamental experiment by the use of packed column. This experiment has been carried out to clear the effect of feed gas flow rate, nitric acid flow rate, nitric acid concentration, and methyl iodide concentration on removal efficiency of methyl iodide. The following results were obtained. The decontamination factor of methyl iodide (DF) increases exponentially with nitric acid concentration, which agrees with the result obtained by using the bubble column. The factor is in inverse proportion to feed gas flow rate, and is also almost independent of nitric acid flow rate and methyl iodide concentration. ...

1978-07-01

101

Regulation and Function of Escherichia coli Sugar Efflux Transporter A (SetA) during Glucose-Phosphate Stress?  

UK PubMed Central (United Kingdom)

Accumulation of certain nonmetabolizable sugar-phosphates (including α-methyl glucoside-6-phosphate) in Escherichia coli is growth inhibitory and elicits the glucose-phosphate...Full Text Available

2011-01-01

102

Prenatal cocaine reduces AMPA receptor synaptic expression through hyperphosphorylation of the synaptic anchoring protein GRIP  

UK PubMed Central (United Kingdom)

Prenatal cocaine exposure produces sustained neurobehavioral and brain synaptic changes closely resembling those of animals with defective alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic...Full Text Available

2009-05-13

103

Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index  

UK PubMed Central (United Kingdom)

The epigenome consists of non–sequence-based modifications, such as DNA methylation, that are heritable during cell division and that may affect normal phenotypes and predisposition...Full Text Available

2010-09-15

104

NOVEL EMBEDDED CERAMIC ELECTRODE SYSTEM TO ACTIVATE NANOSTRUCTURED TITANIUM DIOXIDE FOR DEGRADATION OF MTBE  

Science.gov (United States)

A novel reactor combining a flame-deposited nanostructured titanium dioxide film and a set of embedded ceramic electrodes was designed, developed and tested for degradation of methyl tert-butyl ether (MTBE) in water. On applying a voltage to the ceramic electrodes, a surface coro...

105

Methyl Jasmonate Induces Traumatic Resin Ducts, Terpenoid Resin Biosynthesis, and Terpenoid Accumulation in Developing Xylem of Norway Spruce Stems1  

UK PubMed Central (United Kingdom)

Norway spruce (Picea abies L. Karst) produces an oleoresin characterized by a diverse array of terpenoids, monoterpenoids, sesquiterpenoids, and diterpene resin acids that can protect...Full Text Available

2002-07-01

106

Isolation and identification of flavonoid (-)-4'-methyl-epigallocatechin of roots from Maytemus obtusifolia Mart. (Celastraceae)  

International Nuclear Information System (INIS)

Portuguese ... Orig. Title Isolamento e identificacao do flavonoide (-)-4'-metil-epigalocatequina das raizes de Maytenus obtusifolia Mart. (Celastraceae)

2006-05-19

107

Integrative Analysis of Epigenetic Modulation in Melanoma Cell Response to Decitabine: Clinical Implications  

UK PubMed Central (United Kingdom)

Decitabine, an epigenetic modifier that reactivates genes otherwise suppressed by DNA promoter methylation, is effective for some, but not all cancer patients, especially those with solid tumors. It...Full Text Available

108

Inhibition of lymphocyte-mediated cytolysis by 3-deazaadenosine: Evidence for a methylation reaction essential to cytolysis  

UK PubMed Central (United Kingdom)

3-Deazaadenosine (deazaAdo) inhibits lymphocyte-mediated cytolysis in vitro at micromolar concentrations and is potentiated markedly in this activity by L-homocysteine thiolactone....Full Text Available

1978-12-01

109

Influence of murine leukemia proviral integrations on development of N-methyl-N-nitrosourea-induced thymic lymphomas in AKR mice.  

UK PubMed Central (United Kingdom)

The AKR mouse strain is characterized by a high incidence of spontaneous thymic lymphoma that appears in older animals (greater than 6 months of age) and is associated with novel provirus integrations...Full Text Available

1991-11-01

110

Identification of novel DNA repair proteins via primary sequence, secondary structure, and homology  

UK PubMed Central (United Kingdom)

BackgroundDNA repair is the general term for the collection of critical mechanisms which repair many forms of DNA damage such as methylation or ionizing radiation. DNA repair has...Full Text Available

111

Effect of Inhibition of Acetoclastic Methanogenesis on Growth of Archaeal Populations in an Anoxic Model Environment  

UK PubMed Central (United Kingdom)

Methyl fluoride is frequently used to specifically inhibit acetoclastic methanogenesis, thus allowing determination of the relative contribution of acetate versus H2/CO2 to total...Full Text Available

2006-01-01

112

Dynamin-dependent NMDAR endocytosis during LTD and its dependence on synaptic state  

UK PubMed Central (United Kingdom)

BackgroundThe N-methyl-D-aspartate (NMDA)-type glutamate receptor expressed at excitatory glutamatergic synapses is required for learning and memory and is critical for normal brain...Full Text Available

113

Dual Beneficial Effects of (-)-Epigallocatechin-3-Gallate on Levodopa Methylation and Hippocampal Neurodegeneration: In Vitro and In Vivo Studies  

UK PubMed Central (United Kingdom)

BackgroundA combination of levodopa (L-DOPA) and carbidopa is the most commonly-used treatment for symptom management in Parkinson's disease. Studies have shown that concomitant...Full Text Available

114

DNA methylation and gene expression differences in children conceived in vitro or in vivo  

UK PubMed Central (United Kingdom)

Epidemiological data indicate that children conceived in vitro have a greater relative risk of low birth-weight, major and minor birth defects, and rare disorders involving imprinted...Full Text Available

2009-10-15

115

Copy Number Alterations and Methylation in Ewing's Sarcoma  

UK PubMed Central (United Kingdom)

Ewing's sarcoma is the second most common bone malignancy affecting children and young adults. The prognosis is especially poor in metastatic or relapsed disease. The cell of origin remains elusive,...Full Text Available

2011-01-01

116

Coordination of PAD4 and HDAC2 in the regulation of p53 target gene expression  

UK PubMed Central (United Kingdom)

Histone Arg methylation and Lys acetylation have been found to cooperatively regulate the expression of p53 target genes. Peptidylarginine deiminase 4 (PAD4) is an enzyme that citrullinates...Full Text Available

2010-05-27

117

Comparative pharmacokinetics of two prodrugs of zidovudine in rabbits: enhanced levels of zidovudine in brain tissue.  

UK PubMed Central (United Kingdom)

The pharmacokinetics of two prodrugs of zidovudine (AZT), 1,4-dihydro-1-methyl-3-[(pyridylcarbonyl)oxy] ester and isoleucinyl ester (DPAZT and IAZT, respectively), were investigated in a rabbit model...Full Text Available

1993-04-01

118

Cholinesterases from Plant Tissues  

UK PubMed Central (United Kingdom)

2-Isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine carboxylate methyl chloride (AMO-1618) inhibits the activity of a cholinesterase isolated from mung bean (Phaseolus aureus) roots...Full Text Available

1973-09-01

119

Calcium/Calmodulin-Dependent Protein Kinase II Mediates Hippocampal Glutamatergic Plasticity During Benzodiazepine Withdrawal  

UK PubMed Central (United Kingdom)

Benzodiazepine withdrawal anxiety is associated with potentiation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPAR) currents in hippocampal CA1 pyramidal...Full Text Available

2010-08-01

120

Blood leukocyte DNA hypomethylation and gastric cancer risk in a high-risk Polish population  

UK PubMed Central (United Kingdom)

Global hypomethylation has been shown to increase genome instability potentially leading to increased cancer risk. We determined whether global methylation in blood leukocyte DNA was associated...Full Text Available

2010-10-15

121

Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligand  

UK PubMed Central (United Kingdom)

We investigated the ability of N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide...Full Text Available

2004-08-01

122

No Slide Title - NASA  

Science.gov (United States)

Middleware deployed to help TCP performance over links with large ... Boeing Connex (Ku-Band); INMARSAT Swift 64; TrackNet" 2.0 (Ku-Band); G2.5/G3/G4. General ... Incremental deployment may be difficult; High Link budgets; Link Delay ...

123

Influence of wood extractives in the polymerization of methyl methacrylate by gamma irradiation  

International Nuclear Information System (INIS)

Those materials that can be extracted from pine or oak by ether, ethanol, methyl methacrylate (MMA), or benzene--alcohol all act as inhibitors in the #gamma# polymerization of MMA--wood composites. It was found that preirradiation of either the wood or of the wood--monomer combination reduces or eliminates the inhibitory effect. The most practical industrial solution to this problem is to increase the dose, thereby achieving high molecular polymer in the composite. However, the presence of a maximum in the molecular weight--dose curves means that each wood--monomer pair may have a different optimum dose.

1975-01-01

124

Improved synthesis of (/sup 15/N) 16-Doxyl stearic acid  

Energy Technology Data Exchange (ETDEWEB)

An improved method for the synthesis of (/sup 15/N) 16-Doxyl stearate, a fatty-acid spin label, is reported. The method requires only one mole of (/sup 15/N) 2-amino-2-methyl propanol per mole of methyl keto stearate with an overall yield of about 50%. In contrast, the previous method produced only 1-3% yield. The great improvement in yield was achieved mainly through the reduction of reaction volume which increases the reaction rate by the law of mass action.

1987-10-01

125

A comparative study on the carbon dioxide capture power between 30 wt% 2-amino-2-methyl-1-propanol and 30 wt% methyldiethanol amine aqueous solutions  

Energy Technology Data Exchange (ETDEWEB)

A comparative study has been performed to compare the 30 wt% of 2-amino-2-methyl-1-propanol (AMP) aqueous solution and 30 wt% of methyldiethanol amine (MDEA) aqueous solution to capture carbon dioxide contained in the flue gas stream. The equilibrium constants for each electrolyte reactions have been used to estimate the carbon dioxide absorption process. Henry's constants for each binary pairs between solute gases and solvent have been used to estimate solubility of the gas components.

2009-05-15

126

Third phase formation in the extraction of phosphotungstic acid by TBP in n-octane  

International Nuclear Information System (INIS)

The solvent extraction of 12-phosphotungstic acid, also known as 12-tungstophosphoric acid-H_3PW_1_2O_4_0, the so-called Keggin heteropolyacid - by 0.73 M (20%v/v) tri-n-butyl phosphate (TBP) in n-octane under conditions comparable to those used previously for the extraction of conventional inorganic mineral acids is described. A simplified phase diagram for the pentanary system comprised of H_3PW_1_2O_4_0, HNO_3, H_2O, TBP, and n-octane reveals an extremely low initial concentration of H_3PW_1_2O_4_0 (1.1 mM) at the LOC (limiting organic concentration) condition, far lower than the most effective third-phase-forming inorganic acid, namely HClO_4. The results from small-angle neutron scattering (SANS) indicate that the interparticle attraction energy - U(r) calculated through application of the Baxter sticky sphere model to the SANS data at the LOC condition - ...

2010-08-30

127

Chain radiation-chemical cross-linking of polyethylene under high pressures. [Gamma radiation  

Energy Technology Data Exchange (ETDEWEB)

Regularities in the radiation cross-linking of low-density polyethylene under various conditions of ..gamma..-irradiation were studied. It is shown that at the 0.5 GPa pressure and 450 K the gel formation is initiated at doses of about 1 kGy, i.e. at doses 10 times as low as compared to normal conditions. Abnormally high rate of radiation cross-linking at high temperature and high pressure is an evidence of changes in the mechanism of polyethylene, radiation cross-linking, i.e. of the process transition from nonchain to chain conditions. Decrease in the potential barriers of macroradical reactions with macromolecules is the most probable reason of change in the polymer cross-linking nature.

1984-01-01

128

An ultraviolet-inducible adenosine-adenosine cross-link reflects the catalytic structure of the Tetrahymena ribozyme  

Energy Technology Data Exchange (ETDEWEB)

When a shortened enzymatic version of the Tetrahymena self-splicing intervening sequence (IVS) RNA is placed under catalytic conditions and irradiated at 254 nm, a covalent cross-link forms with high efficiency. The position of the cross-link was mapped by using three independent methods: RNase H digestion, primer extension with reverse transcriptase, and partial hydrolysis of end-labeled RNA. The cross-link is chemically unusual in that it joins two adenosines, A57 and A95. Formation of this cross-link depends upon the identity and concentration of divalent cations present and upon heat-cool renaturation of the IVS in a manner that parallels conditions required for optimal catalytic activity. Furthermore, cross-linking requires the presence of sequences within the core structure, which is conserved among group I intervening sequences and necessary for catalytic activity. Together ...

1990-06-12

129

Probing the H"3 vertex in e"+e"-, #gamma#e, and #gamma##gamma# collisions for light and intermediate Higgs bosons  

International Nuclear Information System (INIS)

We study double Higgs boson production at future linear colliders while paying special attention to the option of high-energy and high-luminosity photon beams. The main purpose is to examine the feasibility of e"+e"-, #gamma#e, and #gamma##gamma# colliders in order to establish bounds on the value of triple Higgs coupling, which could be crucial for understanding a spontaneous breaking mechanism. We consider mainly those cases of light and intermediate Higgs bosons, including an analysis of the electroweak backgrounds. The mass range M_H#approx#M_Z is discussed separately. It is shown that for a light Higgs boson the H"3 coupling can be visible, even at a future linear e"+e"- collider at 500 GeV. For an intermediate Higgs boson, a collider with TeV energies is suitable for investigations. We estimate the bounds on the anomalous H"3 coupling which can be experimentally established at future linear ...

130

Molar extinction coefficients of some fatty acids  

International Nuclear Information System (INIS)

The attenuation of gamma rays in some fatty acids, viz. formic acid (CH_2O_2), acetic acid (C_2H_4O_2), propionic acid (C_3H_6O_2), butyric acid (C_4H_8O_2), n-hexanoic acid (C_6H_1_2O_2), n-caprylic acid (C_8H_1_6O_2), lauric acid (C_1_2H_2_4O_2), myristic acid (C_1_4H_2_8O_2), palmitic acid (C_1_6H_3_2O_2), oleic acid (C_1_8H_3_4O_2) and stearic acid (C_1_8H_3_6O_2), has been measured at the photon energies 81, 356, 511, 662, 1173 and 1332 keV. Experimental values for the molar extinction coefficient, the effective atomic number and the electron density have been derived and compared with theoretical calculations. There is good agreement between experiment and theory.

2002-10-01

131

Electrochemical and conversion electron Moessbauer study of corrosion induced by acid rain  

Energy Technology Data Exchange (ETDEWEB)

The passivation of low carbon steel was studied in aqueous solution of 0.5M Na[sub 2]SO[sub 4]+0.001M NaHSO[sub 3] (pH 3.5, 6.5 and 8.5) which can be considered as a model of acid rain. The used conversion electron Moessbauer spectroscopy (CEMS) with the complementary electrochemical investigations proved that the sulfite ions induce pitting corrosion at pH 3.5 and 6.5, while the measurements showed much weaker pitting at pH 8.5. The compositions and thicknesses of the passive films formed during the electrochemical treatments are determined from the CEM spectra. Only [gamma]-FeOOH was found on the surface of the samples at pH 6.5 and 8.5. Nevertheless, at pH 3.5 the sextet belonging to Fe[sub 3]C appears in the spectra, and also FeSO[sub 4].H[sub 2]O could be detected in low concentration. (orig.).

1993-04-01

132

A study of electrochemically-induced corrosion of low carbon steel in a medium modelling acid rain  

Energy Technology Data Exchange (ETDEWEB)

Complementary electrochemical, spectrophotometric and electron microsopic investigations were made in addition to the conversion electron Moessbauer spectroscopic (CEMS) measurements to learn more about the mechanism of corrosion of low carbon steel samples in aqueous sulfate and sulfite containing sulfate solutions (pH 3.5, 6.5 and 8.5). Passivation of iron in pure sulfate solution was studied in detail in earlier papers. In the present work, we used a solution containing both sulfate and sulfite anions to obtain more information about the effect of acid rain on low carbon steel samples. The compositions and thicknesses of the passive films formed due to the electrochemical treatments were determined from the CEM spectra. [gamma]-FeOOH was found in each case on the surface of the samples; nevertheless, at pH 3.5 the sextet belonging to Fe[sub 3]C appears in the CEM spectra, and also FeSO[sub 4] . H[sub ...

1994-11-01

133

A novel photodiode made of hybrid organic/inorganic nanocomposite  

International Nuclear Information System (INIS)

Novel hybrid organic/inorganic nanocomposites made of metal oxide and conjugated polymer nanocomposite and its application in bulk-heterojunction solar cells were studied. The composite was composed of different concentrations of strontium titanate (SrTiO_3) and polyaniline doped phosphoric acid. The optimum concentration of strontium titanate was found to be 0.2 v/v. An inorganic-organic photovoltaic device with a structure of Ag/Pani-H_3PO_4-SrTiO_3/Al has been fabricated. The ideality factor value of the diode was found to be 1.8. This n value of the diode implies a deviation from ideal junction behaviour. The barrier height #phi#_b value for the diode was found to be 0.56 eV. The Ag/Pani-H_3PO_4-SrTiO_3/Al diode shows a photovoltaic behaviour with a maximum open-circuit voltage V_o_c of 2.49 V, and short-circuit current I_s_c of 5.6 mA under light illumination #lambda# = 460 nm. The conversion ...

2009-08-07

134

Induction and use of sex linked lethal mutations in the pink bollworm  

International Nuclear Information System (INIS)

The sterile insect release technique can often be improved by removal of females before release. Rearing efficiencies can also be increased if removal of the females occurs at early developmental stages. In order to begin to develop genetic sexing strains for the pink bollworm, Pectinophora gossypiella (Saunders), it was necessary to determine the best dosage of radiation for induction of viable sex linked recessive lethal mutations and to see if stocks containing induced sex linked lethals could be maintained in culture. Sex linked recessive lethal mutations can be detected by distorted sex ratios in the progeny of treated adults. However, in the pink bollworm, highly distorted sex ratios are common even in the absence of induced mutations. Therefore, a visible sex linked trait, purple eye, was used as a marker for the untreated X-chromosomes in crosses. Thus, the presence of a recessive sex ...

1987-11-16

135

Molar heat capacities for (2-methyl-2-butanol + heptane) mixtures and cyclopentanol at temperatures from (284 to 353) K  

International Nuclear Information System (INIS)

Isobaric specific heat capacities were measured for (2-methyl-2-butanol + heptane) mixtures and cyclopentanol within the temperature range from (284 to 353) K, and for 2-methyl-2-butanol in the (284 to 368) K temperature interval by means of a differential scanning calorimeter. The excess molar heat capacities were calculated from the experimental results. For the temperature range from (284 to 287) K, the excess molar heat capacity is S-shaped with negative values in the 2-methyl-2-butanol rich region and with small negative values at low alcohol concentrations at temperatures from (295 to 353) K. The excess molar heat capacities are positive for all compositions under test at temperatures from (288 to 294) K. The results are explained in terms of the influence of the molecular size and configuration of the alkanols on their self-association capability and of the change in molecular structure of the ...

2009-03-01

136

Node-Context Network Clustering using PARAFAC Tensor Decomposition  

CERN Document Server

We describe a clustering method for labeled link network (semantic graph) that can be used to group important nodes (highly connected nodes) with their relevant link's labels by using PARAFAC tensor decomposition. In this kind of network, the adjacency matrix can not be used to fully describe all information about the network structure. We have to expand the matrix into 3-way adjacency tensor, so that not only the information about to which nodes a node connects to but by which link's labels is also included. And by applying PARAFAC decomposition on this tensor, we get two lists, nodes and link's labels with scores attached to each node and labels, for each decomposition group. So clustering process to get the important nodes along with their relevant labels can be done simply by sorting the lists in decreasing order. To test the method, we construct labeled link network by using ...

2010-01-01

137

m0307466.imq  

Science.gov (United States)

7&vO BoXl &&td b?f09 `B"Bc ,.q~ G$)ED$O/ Kbwj6rNd CB7"l& KSeU jt#C G"U#V f*,njThh J$,H 3 R!!Z!"" +Jqf el\\V& bb?q~n dS:{ OX[1 HZxR j.$Cs 0B? ...

138

The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth  

UK PubMed Central (United Kingdom)

The Myc oncoprotein is a potent inducer of cell growth, cell cycle progression, and apoptosis. While many direct Myc target genes have been identified, the molecular determinants of Myc’s transcriptional...Full Text Available

2007-03-01

139

Sinterable powders  

International Nuclear Information System (INIS)

A description is given of sinterable powders and methods of producing sintered products using such powders. The powders consist of (a) a particulate ceramic material, e.g. SiC, having specified particle size and surface area; (b) a carbon source material, e.g. sugar or a phenol-formaldehyde resin; and (c) a residue from a solution of H3BO3, B2O3, or mixtures of these as sintering aid. (U.K.).

140

Novel inorganic hydrogen-bonded crystals with nonlinear optical properties  

International Nuclear Information System (INIS)

Four inorganic hydrogen-bonded crystals with second-order nonlinear properties have been discovered: K_4LiH_3(SO_4)_4, Na_2SeO_4#centre dot#H_2SeO_3#centre dot#H_2O, Cs_1_,_5Li_1_,_5H(SO_4)_2 and NH_4HSeO_4. (author)

2000-01-01

141

Direct interband dipole-transition selection rules for the O/sub h//sup 3/ space-group compounds  

Energy Technology Data Exchange (ETDEWEB)

The irreducible representations associated with states of dipole symmetry have been calculated for the space groups O/sub h//sup 3/, the space group with the correct symmetry for A-15 phase compounds. Also assembled are the character tables of the O/sub h/3 group. Thus all thedirect interband dipole-transition selection rules for A-15 compounds can easily be determined.

1983-07-01

142

Connectivity in the Astronomy Digital Library  

CERN Document Server

The Astrophysics Data System (ADS) provides an extensive system of links between the literature and other on-line information. Recently, the journals of the American Astronomical Society (AAS) and a group of NASA data centers have collaborated to provide more links between on-line data obtained by space missions and the on-line journals. Authors can now specify which data sets they have used in their article. This information is used by the participants to provide the links between the literature and the data. The ADS is available at: http://ads.harvard.edu

2006-01-01

143

Biodegradation in oils as a geological natural analogue  

International Nuclear Information System (INIS)

A synthesis of scientific knowledge about petroleum biodegradation linked to uranium mineralisation is firstly done. Then the genesis of Huemul Uranium ore deposit (Malargue Town, Mendoza Province) is discussed, where Uranium ore is linked only with one type of asphaltite (there are three other types) from an oil field close by. This asphaltite type would be an efficient natural geological barrier for Uranium migration and it could be linked to a particular kind of biodegradation. The authors think that the International Wonuc Conference would be a good opportunity to discuss a way for future investigations. (author)

144

BUBL LINK: Computer programming - visual basic  

Wastenet

...BUBL LINK: Computer programming - visual basic BUBL LINK Catalogue of Internet Resources Home | Search | Subject Menus | Countries ...O | P | Q | R | S | T | U | V | W | X | Y | Z Computer programming - visual basic Titles ... Author: Microsoft Subjects: computer programming - visual basic DeweyClass: 005.133 Resource type: software SearchVB....com Subjects: computer programming - visual basic DeweyClass: 005.133 Resource type: index VB Helper Tutorials ...

145

5 GHz 200 Mbit/s radio over polymer fibre link with envelope detection at 650 nm wavelength  

DEFF Research Database (Denmark)

All-optical envelope detection of a 5 GHz 200 Mbit/s modulated radio frequency signal is achieved using a 650 nm resonant cavity light emitting diode. Error-free transmission is achieved over a 50 m-long link of 1 mm diameter graded index polymer optical fibre (POF). The presented system has potential applications in low cost and low complexity short range wireless and wireline POF-based transmission links.

2008-01-01

146

2000 MW HVDC link between England and France  

Energy Technology Data Exchange (ETDEWEB)

The HVDC link across the English Channel, which was brought into service in 1986, has several innovative features. Techniques used in its construction together with recent developments have consolidated the viability of HVDC links for a variety of applications. Outlines the main features of the scheme, including the benefits of interconnecting the British and French 400 kV AC power systems; integration of the UK converter system to the 400 kV AC grid; the DC submarine cables; convertor equipment (particularly the UK installation); and future HVDC developments. 6 refs.

1987-03-01

147

Possible preparation of wood-plastic materials based on unsaturated polyester resins and methyl metacrylate, by radiation and chemical methods in combination  

Energy Technology Data Exchange (ETDEWEB)

The preparation of wood-plastic combinations (WPC) using combined methods for curing intermediate products and final products is described. In the first step, impregnated wood was irradiated using doses of 1 to 10 kGy in the presence of chemical initiators of polymerization. Thereafter, curing of this partly cured impregnating mixture was accomplished in the wood at elevated temperatures with the aid of chemical initiators of polymerization. Impregnation mixtures based on unsaturated polyester resins and methyl methacrylate, and the wood species European Beech (Fagus silvatica) and Black Alder (Alnus glutinosa) were used. The results indicate that this method of preparing WPC allows substantially lower radiation doses to be used, i.e., doses in the range of 1 to 2.5 kGy. These doses gelatinate the impregnation mixture in the wood so that the subsequent curing by chemical polymerization initiators proceeds without the impregnation mixture flowing out of the wood, ...

1982-04-01

148

Possible preparation of wood-plastic materials based on unsaturated polyester resins and methyl metacrylate, by radiation and chemical methods in combination  

International Nuclear Information System (INIS)

The preparation of wood-plastic combinations (WPC) using combined methods for curing intermediate products and final products is described. In the first step, impregnated wood was irradiated using doses of 1 to 10 kGy in the presence of chemical initiators of polymerization. Thereafter, curing of this partly cured impregnating mixture was accomplished in the wood at elevated temperatures with the aid of chemical initiators of polymerization. Impregnation mixtures based on unsaturated polyester resins and methyl methacrylate, and the wood species European Beech (Fagus silvatica) and Black Alder (Alnus glutinosa) were used. The results indicate that this method of preparing WPC allows substantially lower radiation doses to be used, i.e., doses in the range of 1 to 2.5 kGy. These doses gelatinate the impregnation mixture in the wood so that the subsequent curing by chemical polymerization initiators proceeds without the impregnation mixture flowing out of the wood, ...

1982-01-01

149

Oil palm empty fruit bunch (OPEFB) fiber reinforced PVC/ENR blend-electron beam irradiation  

Energy Technology Data Exchange (ETDEWEB)

The effect of irradiation on the tensile properties of oil palm empty fruit bunch (OPEFB) fiber reinforced poly(vinyl chloride)/epoxidized natural rubber (PVC/ENR) blends were studied. The composites were prepared by mixing the fiber and the PVC/ENR blend using HAAKE Rheomixer at 150 deg. C. The composites were then irradiated by using a 3.0 MeV electron beam machine at doses ranging from 0 to 100 kGy in air and room temperature. The tensile strength, Young's modulus, elongation at break and gel fraction of the composites were measured. Comparative studies were also made by using poly(methyl acrylate) grafted OPEFB fiber in the similar blend system. An increase in tensile strength, Young's modulus and gel fraction, with a concurrent reduction in the elongation at break (Eb) of the PVC/ENR/OPEFB composites were observed upon electron beam irradiation. Studies revealed that grafting of the OPEFB fiber with methyl acrylate did ...

2007-12-15

150

Modulation of gene expression in differentiating 3T3 - L1 preadipocytes  

Energy Technology Data Exchange (ETDEWEB)

3T3 - L1 cells can be induced to differentiate by exposing cell culture to a medium containing 3-isobutyl-1-methyl-xanthine together with insulin and dexamethasone. They have observed that oxalomalate (OMA) which inhibits aconitase thus blocking the citric cycle, also favours differentiation to adipocytes leading to fatty acids accumulation and increased synthesis of specific proteins. They compared the effects of 3-isobutyl-1-methyl-xanthine-insulin-dexamethasone and OMA on the steady-state levels of mRNA of c / EBP, H-ferritin and aconitase / IRE-BP. OMA does not affect the steady-state mRNA amount of C / EBP, H-ferritin and aconitase / IRE-BP but the 3-isobutyl-1-methyl-xanthine-insulin-dexamethasone mixture is able to induce a five-fold increase of mRNA levels for aconitase / IRE-BP. This is the first finding correlating iron metabolism to adipocyte differentiation. Further studies will clarify a possible role for the ...

1997-12-31

151

Methyl bromide and methyl chloride fluxes from temperate forest litter  

British Library Electronic Table of Contents (United Kingdom)

Methyl halide fluxes were measured from fine (nonwoody) litter samples at a temperate deciduous forest site in Scotland on 16 occasions over more than a year and at a coniferous forest site. The resulting mean (+-1 sd) CH3Br and CH3Cl fluxes were 4.1 +- 3.7 ng kg-1 h-1 and 0.98 +- 0.62 mg kg-1 h-1, respectively, for dry mass leaf litter and 5.7 +- 6.3 ng kg-1 h-1 and 0.47 +- 0.14 mg kg-1 h-1 for dry mass needle litter. Temporal variations of net fluxes from leaf litter were significantly greater than spatial variations suggesting seasonality in the fluxes. The mean CH3Cl/CH3Br mass ratio of fluxes was 200 (to 1 sig. fig.), an order of magnitude larger than the ratio of their estimated global turnovers. Temperate forest litter may be a moderate net source of CH3Cl globally but a negligible ...

2011-01-01

152

Kinetic aspects of the photolysis of in-station airborne methyl iodide  

International Nuclear Information System (INIS)

A method for converting organic iodides to elemental iodine would be advantageous in improving the performance of charcoal filters for the removal of radio iodines from reactor off gases. A photochemical method has been developed. The HAVCHM code was used to establish the relevant process time scales on a complete set of rate equations describing the primary and secondary reactions occurring in a plug-flow reactor containing low levels of elemental iodine and methyl iodide in air, which is irradiated by intense u.v. light. These simulations were used to justify the contraction of the complete set of reactions to the most significant elementary processes. The contracted set of rate equations are then solved analytically to render the concentration-time profiles of methyl iodide, total inorganic iodine and total oxidized organics, consistent with the achievement of a desirable radioiodine decontamination factor. For the short contact times ...

153

Investigation of enzymatic biodiesel production using ionic liquid as a co-solvent  

Energy Technology Data Exchange (ETDEWEB)

Ionic liquids can enhance the activity, selectivity, and stability of enzyme catalysts. Enzymes and ionic liquids as catalysts are seen as a more environmentally friendly technology than the use of traditional catalyst materials in biofuels production. This study investigated the lipase catalyzed esterification reaction for biodiesel production in the presence of the ionic liquid BMIM PF{sub 6}. Methyl acetate was used as the acyl acceptor. A titremetric assay was conducted to measure the activity of the lipase with various amounts of ionic liquid. Reaction parameters were investigated in order to determine their effects on biodiesel conversion. An 80 per cent overall methyl oleate biodiesel yield was successfully produced in the presence of the ionic liquid. The ionic liquid improved lipase activity as well as overall biodiesel yield. Results also showed that the addition of the ionic liquid facilitated the separation of ...

2010-04-15

154

Formation of methyl formate and other organic species in the warm-up phase of hot molecular cores  

CERN Document Server

Aims: The production of saturated organic molecules in hot cores and corinos is not well understood. The standard approach is to assume that, as temperatures heat up during star formation, methanol and other species evaporate from grain surfaces and undergo a warm gas-phase chemistry at 100 K or greater to produce species such as methyl formate, dimethyl ether, and others. But a series of laboratory results shows that protonated ions, typical precursors to final products in ion-molecule schemes, tend to fragment upon dissociative recombination with electrons rather than just ejecting a hydrogen atom. Moreover, the specific proposed reaction to produce protonated methyl formate is now known not to occur at all. Methods: We utilize a gas-grain chemical network to probe the chemistry of the relatively ignored stage of hot core evolution during which the protostar switches on and the temperature of the surrounding gas and dust rises from 10 K to ...

2006-01-01

155

Effect of processing on pirimiphos-methyl residues in stored peanuts  

International Nuclear Information System (INIS)

Peanut grains (1500g) were placed in a jute sack which was sprayed with "1"4C- pirimiphos-methyl [0-2-diethylamino-6-methylpyrimidin-4-yl-O, O-dimethylphosphorothiate, "1"4C-labelled in the 2-position of the pyrimidine ring]; total dose 5.55 MBq + 22.5 mg cold insecticide. As in practice, the sack was stored under local conditions for 36 weeks. The grain was crushed, dried at 50 deg. C for 2 hours and soxhlet extracted with chloroform-methanol (1:1). The crude oil was then subjected to sequential processes of alkali treatment, bleaching and deodorization. The initial residue concentration in the crude oil (5.66 ppm) was reduced to 4.50 ppm through alkali treatment and declined further to 3.78 ppm after bleaching. Deodorization removed a substantial amount of "1"4C-residues leaving 1.35 ppm in the refined oil. It may be concluded that simulated commercial processing of crude oil were capable of removing 76% of pirimiphos-methyl and/or products. ...

1995-08-01

156

Combustion of biodiesel fuel produced from hazelnut soapstock/waste sunflower oil mixture in a Diesel engine  

International Nuclear Information System (INIS)

Biodiesel is considered as an alternative fuel to Diesel fuel No. 2, which can be generally produced from different kinds of vegetable oils. Since the prices of edible vegetable oils are higher than that of Diesel fuel No. 2, waste vegetable oils and non-edible crude vegetable oils are preferred as potential low priced biodiesel sources. In addition, it is possible to use soapstock, a by-product of edible oil production, for cheap biodiesel production. In this study, a methyl ester biodiesel was produced from a hazelnut soapstock/waste sunflower oil mixture using methanol, sulphuric acid and sodium hydroxide in a two stage process. The effects of the methyl ester addition to Diesel No. 2 on the performance and emissions of a four cycle, four cylinder, turbocharged indirect injection (IDI) Diesel engine were examined at both full and partial loads. Experimental results showed that the hazelnut soapstock/waste sunflower oil ...

2005-03-01

157

link0303e.fm  

Wastenet

Producer: Acrobat Distiller 3.02 ...Volume 3 Number 3 28 July 1998 ...Volume 3 Number 3 27 July 1998 It is in this context that all countries,

158

Vitamins C and E to Prevent Complications of Pregnancy-Associated Hypertension  

UK PubMed Central (United Kingdom)

BackgroundOxidative stress has been proposed as a mechanism linking the poor placental perfusion characteristic of preeclampsia with the clinical manifestations of...Full Text Available

2010-04-08

159

USAID Health: Overview  

Science.gov (United States)

Careers Business / Policy USAID: From The American People - Link to USAID Home Page Health USAID's 50th Anniversary Health Overview » Overview Technical Areas Countries...

2011-08-28

160

U.S. Department of the Interior Library - Reference Sources on...  

Science.gov (United States)

and Vendors on the Web Bartleby.com "Great books online." Electronic Texts & Digital Libraries Links to the full text of books and other texts on the Web. Law and Politics...

2011-05-06

161

The influence of tertiary structural restraints on conformational transitions in superhelical DNA.  

UK PubMed Central (United Kingdom)

This paper examines theoretically the effects that restraints on the tertiary structure of a superhelical DNA domain exert on the energetics of linking and the onset of conformational transitions. The...Full Text Available

1987-12-10

162

The Effects of Magnesium on State 3 Respiration of Liver Mitochondria from Control and Cold-Acclimated Rats and Hamsters  

Science.gov (United States)

Increasing the Mg(2+) concentration results in a depression of succincoxidase-linked state 3

1978-01-01

163

The Current Status of Russian/CIS Communication Satellites  

Science.gov (United States)

... 4302, and to the Office of Management and Budget, Paper-work ... link coverage areas, so it is possible to receive your own ... mestic Ku-band satellite. ...

1994-09-01

164

Strategic Communication: A Department of Defense Approach  

Science.gov (United States)

... development of SC policy within DOD, because it describes the necessary link between DOD ... strategy convolutes USG efforts to develop SC policy. ...

2007-03-28

165

Spread spectrum acquisition and tracking performance for Shuttle communication links  

Science.gov (United States)

The spread spectrum acquisition and tracking performance for the Shuttle S-band and Ku-band communication links are analyzed and compared to test results. The S-band link requirements are more severe than those of the Ku-band links, hence, different despreader designs were developed for the two systems. The S-band despreader acquires pseudonoise code lock by examining all possible code phases in half chip steps while the Ku-band despreader acquires pseudonoise code lock by continuously sweeping a tau-jitter loop. Both despreaders employ a tau-jitter loop for code tracking. The code tracking performance is computed for the tau-jitter loop and compared to that of the more complex delay lock loop.

1978-01-01

166

Space Weather Prediction Center Education and Outreach  

Science.gov (United States)

Education resources dealing with solar-terrestrial physics, solar effects, solar radiation, etc. Includes links to short reference papers on subjects ... ...

167

Soybean Rust Economic Assessment  

Science.gov (United States)

& International Markets Bottom of Browse By Subject You are here: Home / Featuring / Soybean Rust Featuring Print this page Print | E-mail this link E-mail | Bookmark & Share...

2011-10-01

168

Sentence Processing: Linking Language to Motor Chains  

UK PubMed Central (United Kingdom)

A growing body of evidence in cognitive science and neuroscience points towards the existence of a deep interconnection between cognition, perception and action. According to this embodied perspective...Full Text Available

169

STS067-703D-090 Kinshasa ... - Earth from Space - Image Information  

Science.gov (United States)

... rivers of the world, the Zaire is not an efficient transportation link because of many rapids and falls to negotiate between Kinshasa and the port city of Matadi. ...

170

Public Health, Commissioned Corps  

Science.gov (United States)

may experience difficulty opening the Facebook page due to current HHS policy and network security that blocks access to the site. Site Map - Contact Us - Linking to USPHS.gov -...

2011-10-16

171

Predictors of Fat Stereotypes among 9-Year-Old Girls and Their Parents  

UK PubMed Central (United Kingdom)

ObjectiveTo assess familial links in fat stereotypes and predictors of stereotypes among girls and their parents.Research Methods and...Full Text Available

2004-01-01

172

Optimism and Physical Health: A Meta-analytic Review  

UK PubMed Central (United Kingdom)

BackgroundPrior research links optimism to physical health, but the strength of the association has not been systematically evaluated.PurposeFull Text Available

2009-06-01

173

Mangroves in the Gulf of California increase fishery yields  

UK PubMed Central (United Kingdom)

Mangroves are disappearing rapidly worldwide despite their well documented biodiversity and the ecosystem services they provide. Failure to link ecological processes and their societal benefits has...Full Text Available

2008-07-29

174

MST Division Work for Others  

Science.gov (United States)

[[pdf] Reference Guide for Proposals 07/09 [pdf] FY11 Overhead Rate Calculator (xls) DARPA Opportunities NIH Proposals (Leads & Subcontractors) [NIH Office] Related Links MST...

2011-08-27

175

Insulin therapy in critically ill patients  

UK PubMed Central (United Kingdom)

Hyperglycemia frequently occurs with acute medical illness, especially among patients with cardiovascular disease, and has been linked to increased morbidity and mortality in critically ill patients....Full Text Available

2010-01-01

176

If I Had - A Bruit In My Neck  

Medline Plus

... Pressure Monitoring Better Than Office-Based, Stressful Work Environment Increases Cardiovascular Risks, Diesel Exhaust Linked to COPD ...

177

INJECTABLE IN SITU CROSS-LINKING HYDROGELS FOR LOCAL ANTIFUNGAL THERAPY  

UK PubMed Central (United Kingdom)

Invasive fungal infections can be devastating, particularly in immunocompromised patients, and difficult to treat with systemic drugs. Furthermore, systemic administration of those medications...Full Text Available

2010-02-01

178

Health Topics beginning with A - National Institutes of Health...  

Science.gov (United States)

Skip Over Navigation Links U.S. Department of Health & Human Services National Institutes of Health NIH...Turning Discovery into Health For Employees Staff Directory En Español...

2011-08-26

179

Health Information Technology and Physician Career Satisfaction  

UK PubMed Central (United Kingdom)

PurposeHealth information technology (HIT) and physician career satisfaction are associated with higher-quality medical care. However, the link between HIT and physician...Full Text Available

180

GLAST Project Status - NASA  

Science.gov (United States)

Space Network Ku-band service. ... Completed GLAST mission schedule and budget assessment .... Utilize Ku band SN link (TDRSS) for science data return ...

181

Fronto-limbic Functioning in Children and Adolescents With and Without Autism  

UK PubMed Central (United Kingdom)

We used neuropsychological tasks to investigate integrity of brain circuits linking orbitofrontal cortex and amygdala (orbitofrontal-amygdala), and dorsolateral prefrontal cortex and hippocampus...Full Text Available

2008-01-15

182

Fatigue Is a Predictor for Cardiovascular Outcomes in Patients Undergoing Hemodialysis  

UK PubMed Central (United Kingdom)

Background and objectives: Despite potential significance of fatigue and its underlying components in the occurrence of cardiovascular diseases, epidemiologic data showing the link are virtually limited....Full Text Available

2010-04-01

183

Evaluating concentration estimation errors in ELISA microarray experiments  

UK PubMed Central (United Kingdom)

BackgroundEnzyme-linked immunosorbent assay (ELISA) is a standard immunoassay to estimate a protein's concentration in a sample. Deploying ELISA in a microarray format permits simultaneous...Full Text Available

184

Direct Detection Optical Intersatelllte Link at 220 Mbps Using ...  

Science.gov (United States)

on this technology has beenproposedas a payload on SpaceStation Freedom to be launched in the near future [1]. Direct detection 4-ary pulse position modula- ...

185

Deforestation in Mato Grosso, Brazil - NASA  

Science.gov (United States)

Deforestation in Mato Grosso, Brazil. atom_author. atom_name, Jesse Allen. atom_link. kml_href, http://earthobservatory.nasa.gov/Feeds/GoogleEarth/ ...

186

DefenseLINK News: Third Contingency Exercise Deployment ...  

Science.gov (United States)

... The contingency readiness exercises began in July when a company of soldiers from the Army's 82nd Airborne Division deployed to Haiti for an ...

187

DefenseLINK News: Proposed FMS to Egypt - High Mobility ...  

Science.gov (United States)

... The Government of Egypt has requested a possible sale of 239 High Mobility Multi-purpose Wheeled Vehicles (HMMWV), electronic test set, spare ...

188

DefenseLINK News: General and Flag Officer Assignments  

Science.gov (United States)

... Ward, William E. Brigadier General, Assistant Division Commander (Support), 82nd Airborne Division, Fort Bragg, North Carolina, Chief, Office of ...

189

DefenseLINK News: General Officer Assignments Announced ...  

Science.gov (United States)

... SMITH, EDWIN P. Assistant Division Commander, Commanding General, United States tbd Brigadier General 82nd Airborne Division, Fort Bragg ...

190

DefenseLINK News: General Officer Assignments  

Science.gov (United States)

... Ward, William E. Brigadier General, Assistant Division Commander (Support), 82nd Airborne Division, Fort Bragg, NC, Chief, Office of Military ...

191

DefenseLINK News: Flag and General Officer Assignments  

Science.gov (United States)

... Schmader, John R. Brigadier General, Assistant Division Commander (Operations), 82nd Airborne Division, Ft. Bragg, NC, ...

192

DefenseLINK News: Exercise Fairwinds begins Tuesday ...  

Science.gov (United States)

... This series of contingency readiness exercises began in July when a company of soldiers from the Army's 82nd Airborne Division deployed to Haiti ...

193

DefenseLINK News: DoD Selected Acquisition Report  

Science.gov (United States)

... Change $ -37.0. June 1996 (70 programs*) $ 707,771.1. *Excludes classified costs for the Air Force's MILSTAR program. As of ...

194

DefenseLINK News: Department of Army General Officer ...  

Science.gov (United States)

... Staff for Policy, Supreme Headquarters, Allied Powers ... Command/United States Forces Korea, Korea, Commander, Joint Task Force for Full ...

195

DefenseLINK News: Combined US- Australian Exercise ...  

Science.gov (United States)

... the USCINCPAC staff and the staff of the commander, US Seventh Fleet, as a designated Pacific Command Joint Task Force Headquarters, in crisis ...

196

DefenseLINK News: Brig Gen's for promotion to the grade of ...  

Science.gov (United States)

... Ground, Maryland 21005 Brigadier General Edwin P. Smith Assistant Division Commander 82nd Airborne Division Fort Bragg, North Carolina ...

197

CIVIL USES OF REMOTELY PILOTED AIRCRAFT' - NASA Technical Report ...  

Science.gov (United States)

to, an altitude of 5000 ft (1500 m) AGL and f4.ies tight circles. If link has ...... The learning-curve effect reflects the observable ...

198

BOOKMARKS:  

Wastenet

2. 1.3. 1.4. ...2.1. 2.2 . 2.3. ...2.4. 2.5. 2.6. 2.7.Global air temperature change Natural disasters linked to climate

199

A heating surface  

Energy Technology Data Exchange (ETDEWEB)

A design is proposed for forming the rear screen of a chamber firebox at the point of aerodynamic projection and a design for attaching the pipes of the aerodynamic projection using girders linked with the screen by hinges and movable connections.

1982-01-01

200

A Network Coding Approach to Loss Tomography  

CERN Document Server

Network tomography aims at inferring internal network characteristics based on measurements at the edge of the network. In loss tomography, in particular, the characteristic of interest is the loss rate of individual links. There is a significant body of work dedicated to this problem using multicast and/or unicast end-to-end probes. Independently, recent advances in network coding have shown that there are several advantages from allowing intermediate nodes to process and combine, in addition to just forward, packets. In this paper, we pose the problem of loss tomography in networks that have network coding capabilities. We design a framework for estimating link loss rates, which leverages network coding capabilities and we show that it improves several aspects of tomography, including the identifiability of links, the tradeoff between estimation accuracy and bandwidth efficiency, and the complexity of probe path ...

2010-01-01

201

--No Title--  

Science.gov (United States)

National Institutes of Health Mucosal Immunology and Microbiome Interest Group Search Go Search Skip Navigation Links SIGS > Mucosal Immunology and Microbiome Interest Group Skip...

2011-10-08

202

 

Wastenet

Pages 184-197: Understanding Personal Change in a Women’s Faith-Based Transitional Center/title link ...titleUnderstanding Personal Change in a Women’s Faith-Based Transitional Center/dc:title

203

Wood-polymer composites. Polymerization of methyl-metacrylate in Pinus strobus var. chiapensis wood by gamma radiation  

Energy Technology Data Exchange (ETDEWEB)

To obtain Pinus wood-plastic composites, wood samples were impregnated with methyl methacrylate and polymerized by the use of gamma rays from a /sup 60/Co at different dose exposure and total dose. The best percentage of polymerization was obtained with the exposure of 2.0 MR of gamma radiation. It was found that the impregnation and polymerization, determined by the density values along the samples were uniform. The density became 2.6 times higher in relation to the control samples. The storage of the impregnated wood samples showed losses of the monomer, even when wrapped with aluminum or polyethylene film. It is recommended that the wood samples should be irradiated soon after impregnation.

1984-12-01

204

Use of lanthanide shift reagents together with silver trifluoroacetate for quantitative analysis of mixtures of aromatic hydrocarbons  

Energy Technology Data Exchange (ETDEWEB)

The shifts induced by equimolar mixture of typical lanthanide shift reagent such as 2,2-dimethyl-6,6,7,7,8,8,8-heptafluoro-3,5-octadionato europium with silver trifluoroacetate in /sup 1/H NMR spectra of aromatic hydrocarbons have been used for analytical purposes; the NMR determination of m- and p-xylenes in mixtures has been chosen as an example. The use has been made of the difference between induced shifts of methyl group signals in the /sup 1/H NMR spectra of m- and p-xylenes. The magnitude of induced shifts of methyl groups signal in m-xylene is always larger than that of p-isomer, irrespective of contents of m- and p-xylenes in mixture.

1980-01-01

205

Spectroscopy and photophysics of mono methyl-substituted alloxazines  

Energy Technology Data Exchange (ETDEWEB)

Singlet-singlet and triplet-triplet absorption spectra of a series of methyl-alloxazines were calculated using the time-dependent density-functional theory approach and compared to experimental results. The B3LYP functional provides good correlation between experimental and theoretical results, given that solvent effects are disregarded in the present calculations. Substituent and solvent dependences of the lowest, closely spaced, n,{pi}* and {pi},{pi}* excited state energies are discussed, their order being of consequence in determining the non-radiative decay rates and thus emission quantum yields and lifetimes. The high quantum yields of singlet oxygen formation indicate that the triplet state is formed by efficient intersystem crossing from the first singlet excited state.

2004-05-31

206

Selective changes of retroelement expression in human prostate cancer  

British Library Electronic Table of Contents (United Kingdom)

Retroelements constitute a large part of the human genome. These sequences are mostly silenced in normal cells, but genome-wide DNA hypomethylation in cancers might lead to their re-expression. Whether this re-expression really occurs in human cancers is largely unkown. We therefore investigated expression and DNA methylation of several classes of retroelements in human prostate cancer tissues and cell lines by quantitative reverse transcription-polymerase chain reaction and pyrosequencing, respectively. The most striking finding was strong and generalized increased expression of the HERV-K_22q11.23 provirus in cancers, including de novo expression of a spliced accessory Np9 transcript in some tumors. In parallel, DNA methylation in the long terminal repeat (LTR) decreased. Conversely, HER...

2011-01-01

207

Selected cardiovascular and central properties of three lidocaine analogs.  

Science.gov (United States)

Three analogs of lidocaine (benzyl carbamyl, benzyl nitrile and methyl nitrile) were synthesized and examined for cardiovascular and central activity. The benzyl carbamyl analog was more potent than lidocaine in lowering blood pressure but possessed only slight local anesthetic, antiarrhythmic and CNS-depressant activity. At 40 mg/kg the benzyl nitrile derivative was superior to lidocaine in protecting against chloroform-induced arrhythmias. The methyl nitrile analog was less active than the benzyl nitrile analog in most parameters examined. The benzyl nitrile derivative and lidocaine had similar potencies on blood pressure depression, local anesthetic activity and ability to protect against calcium chloride-induced arrhythmias. Unlike the benzyl carbamyl derivative both lidocaine and the benzyl nitrile compounds appear to depress the cardiovascular system via a common mechanism. PMID:515167

1979-01-01

208

Process for filling tubular plates for lead batteries. Verfahren zum Fuellen von Rohrplatten fuer Bleiakkumulatoren  

Energy Technology Data Exchange (ETDEWEB)

The following method is proposed as a supplement to main patent 2419107, which deals with the filling of tubular plates surrounding the lead cores: the flat materials which are used to produce the jacket tubes are prepared before forming into jacket tubes by a film producing aqueous carboxy-methyl cellulose solution closing the pores. The preparation can be done by coating the flat material with a soluble foil. After pressing the paste in, the tubular plates are dried and after cooling are dipped into sulphuric acid with a specific gravity of 1.24 g/cm/sup 3/. The carboxy-methyl cellulose is dissolved and the permeability of the tube walls for electrolyte is restored after only 15 minutes.

1981-06-19

209

Molecular dynamics study of TiO2/poly(acrylic acid-co-methyl methacrylate) and Fe3O4/polystyrene composite latex particles prepared by heterocoagulation  

British Library Electronic Table of Contents (United Kingdom)

All-atom molecular dynamics simulations were used to study the morphology of polymer/inorganic composite particles prepared by heterocoagulation. The results were also compared to those of our previous study of the preparation of TiO2/poly(acrylic acid-co-methyl methacrylate) and Fe3O4/polystyrene composite particles. In the simulation system, polymer or inorganic particles were simulated by surface-charge-modified C60 or Na atoms. Through a combination of analysis of the radial distribution functions of charged atoms and snapshots of the equilibrated structure, three kinds of particle distributions were observed under different conditions. When the polymer and inorganic particles had opposite surface charges and their sizes were very different, the composite morphology showed a core-shell...

2010-01-01

210

Infrared spectroscopy of rovibrational transitions of methyl radicals (CH3, CD3) in solid parahydrogen  

British Library Electronic Table of Contents (United Kingdom)

The n3 and n4 vibrational transitions of CH3 and CD3 isolated in solid parahydrogen were studied by high-resolution infrared spectroscopy. The radicals were produced by in situ UV photolysis of methyl iodides trapped in solid parahydrogen. The observed spectra showed clear rotational fine structures, which were subjected to further splitting due to the electrostatic field of solid parahydrogen. The molecular constants and crystal field parameters of the radicals in solid parahydrogen were determined by analyzing the spectral structures of the n3 and n4 transitions of CD3 by the crystal field theory. The rotational constants of the CD3 radical were found to be only a few percent smaller than those in the gas phase. The determined crystal field parameters indicated significant quantum effect...

2011-01-01

211

Hydrogen-atom attack on methyl viologen in aqueous solution studied by pulse radiolysis  

International Nuclear Information System (INIS)

Using hydrogen at high pressures of up to 150 bar as an OH scavenger in aqueous MV"2"+ solutions (pH 1) it is possible to differentiate between two kinds of transient formed simultaneously by H-atom attack on methyl viologen. One of them is assigned to an H adduct on the N atom, MV"+H"+, with absorption bands identical to those of the radical cation, MV"+. The MV"+H"+ species deprotonates forming the long-lived radical cation, MV"+. The second type of transient produced is attributed to an H-adduct on the ring carbon, MV"2"+H, decaying by second-order kinetics. The formation of MV"+ by electron transfer from the propan-2-ol radical has been reinvestigated (pH 0 to 7); its absorption spectrum does not change in this pH range. Rate constants and molar extinction coefficients are presented. (U.K.).

1984-01-01

212

Epigenetic regulation of Myc on retinoic acid receptor beta and PDLIM4 in RWPE1 cells  

British Library Electronic Table of Contents (United Kingdom)

BACKGROUND Hypermethylation of CpG islands is a common epigenetic alteration associated with cancer. Tumor suppressor genes retinoic acid receptor beta (RARb) and PDLIM4 are hypermethylated and silenced in prostate cancer (PCa) tissues and PCa cell lines compared to normal prostate cells. METHODS In this study, a benign prostate epithelial cell line RWPE1 was used as a model to study the epigenetic regulation of Myc on the RARb and PDLIM4 promoters. Forced Myc overexpression inhibited the RARb and PDLIM4 expression. RESULTS Pyrosequencing study showed that Myc overexpression increased methylation in several CpG sites of both promoters. A DNA methylation inhibitor 5-aza-2prime-deoxycytidine reversed the epigenetic alteration effect of Myc on both RARb and PDLIM4. CONCLUSION The epigenetic r...

2009-01-01

213

Enhancement of PVC/ENR blend properties by poly(methyl acrylate) grafted oil palm empty fruit bunch fiber  

British Library Electronic Table of Contents (United Kingdom)

Effect of oil palm empty fruit bunch (OPEFB) fiber and poly(methyl acrylate) grafted OPEFB on several mechanical properties of poly(vinyl chloride)/epoxidized natural rubber (PVC/ENR) blends were studied. The composites were prepared by mixing the fiber and the PVC/ENR blends using HAKEE Rheomixer at the rotor speed of 50 rpm, mixing temperature 150degreeC, and mixing period of 20 min. The fiber loadings were varied from 0 to 30% and the effect of fiber content in the composites on their ultimate tensile strength (UTS), Youngs modulus, elongation at break, flexural modulus, hardness, and impact strength were determined. An increasing trend was observed in the Youngs modulus, flexural modulus, and hardness with the addition of grafted and ungrafted fiber to the PVC/ENR blends. However the i...

2008-01-01

214

Degradation of organophosphorus pesticides in wheat during cookie processing  

British Library Electronic Table of Contents (United Kingdom)

For investigating carryover of some organophosphorus pesticide residues in the cereal food chain from grain to consumer, a study was set up on wheat bran, flour and cookies, with and without bran. Special emphasis was given to malathion and chlorpyrifos-methyl residues in cookies for better protection of consumers. Pesticide-free wheat was placed in a small-scale model of a commercial storage vessel and treated with these pesticides. The residue levels of insecticides were determined in wheat, as well as in bran, flour and cookies produced from stored wheat at various time intervals during storage. A multiresidue analysis was performed using GC-NPD and GC-MS. Malathion and chlorpyrifos-methyl residue levels were higher than the maximum residue limits (MRLs) in wheat after 240days of storag...

2009-01-01

215

Chemical cotton stalk destruction for maintenance of host-free periods for the control of overwintering boll weevil in tropical and subtropical climates  

British Library Electronic Table of Contents (United Kingdom)

In the Lower Rio Grande Valley (LRGV) of Texas, cotton regrows and produces fruit from undestroyed stalks throughout the winter, and in spring weevils from such locations become a serious threat. The success of the boll weevil eradication program, which was reintroduced in the LRGV in 2005, will be dependent on thorough stalk destruction following harvest. However, adverse weather conditions and conservation tillage often impede immediate and complete stalk destruction using typical tool implements, and alternative stalk control methods are needed. This study provides an examination of the efficacy for cotton stalk destruction of different herbicides (thifensulfuron-methyl + tribenuron-methyl, dicamba-diolamine, 2,4-D-dimethylammonium, flumioxazin, 2,4-DB-dimethylammonium and carfentrazone...

2007-01-01

216

Characterization and effect of using cotton methyl ester as fuel in a LHR diesel engine  

International Nuclear Information System (INIS)

In the present study, surfaces of cylinder head, piston, exhaust and inlet valve of a four-stroke, direct injection, single cylinder diesel engine were coated with molybdenum (Mo) by plasma spray method. Thus, thermal barrier characteristic was brought to these parts. Variances in performance and emission values of cotton methyl ester and 2D fuel mixtures were studied in the ceramic coated and uncoated engines under the same running conditions. Performance (6.0% for specific fuel consumption) and emission values (up to 18.0% for CO, 8.0% for smoke density) of the test fuel were improved in the coated engine compared with the uncoated engine. NO_x increase (4.5%) with the increased temperatures expected in the coated engine.

2011-01-01

217

Blood gene expression markers to detect and distinguish target organ toxicity  

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study was to investigate whether the expression of specific genes in peripheral blood can be used as surrogate marker(s) to detect and distinguish target organ toxicity induced by chemicals in rats. Rats were intraperitoneally administered a single, acute dose of a well-established hepatotoxic (acetaminophen) or a neurotoxic (methyl parathion) chemical. Administration of acetaminophen (AP) in the rats resulted in hepatotoxicity as evidenced from elevated blood transaminase activities. Similarly, administration of methyl parathion (MP) resulted in neurotoxicity in the rats as evidenced from the inhibition of acetyl cholinesterase activity in their blood. Administration of either chemical also resulted in mild hematotoxicity in the rats. Microarray analysis of the global ...

2010-01-01

218

The EnviroLink Network - RTK Net  

Wastenet

... (last modified: 10/22/2002) Organizations Saratoga Foundation (last modified: 02/11/2003) Actions You Can Take Global Response (last modified: 05/10/2000) Organizations University of Pittsburgh Cancer Institute - Center for Environmental Oncology (last modified: 01/14/2005) Home | Site Map | About EnviroLink | Advanced Search | Suggest ...

219

On the spectral sequence from Khovanov homology to Heegaard Floer homology  

CERN Document Server

Ozsvath and Szabo show that there is a spectral sequence whose E^2 term is the reduced Khovanov homology of L, and which converges to the Heegaard Floer homology of the (orientation reversed) branched double cover of S^3 along L. We prove that the E^k term of this spectral sequence is an invariant of the link L when k>2. If L is a transverse link, then we show that Plamenevskaya's transverse invariant gives rise to a transverse invariant of L in each of these higher terms.

2008-01-01

220

High throughput protein fold identification by using experimental constraints derived from intramolecular cross-links and mass spectrometry  

UK PubMed Central (United Kingdom)

We have used intramolecular cross-linking, MS, and sequence threading to rapidly identify the fold of a model protein, bovine basic fibroblast growth factor (FGF)-2. Its tertiary structure was probed...Full Text Available

2000-05-23

221

Glutamine-linked and Non-consensus Asparagine-linked Oligosaccharides Present in Human Recombinant Antibodies Define Novel Protein Glycosylation Motifs  

UK PubMed Central (United Kingdom)

We report the presence of oligosaccharide structures on a glutamine residue present in the VL domain sequence of a recombinant human IgG2 molecule. Residue Gln-106, present in the QGT sequence...Full Text Available

2010-05-21

222

Effect of lifetime nutrition on ruminant carcass and meat quality  

Environmental Research Database

DescriptionThis application is a request for Bridge Link funds to support studies in order to develop a full proposal under the Link Sustainable Livestock Scheme in collaboration with Dr Nigel Scollan of IGER. The hypothesis being examined is that the poor performance of some ruminants is due to poor nutrition at strategic time points during the animal's development. The initial hypothesis will be tested in sheep and the results from this will be used to develop the full proposal. Excessive fat in ruminan [continued...

2006-01-31

223

Determination by enzyme-linked immunosorbent assay of immunoglobulin G (IgG), IgM, and IgA to Brucella melitensis major outer membrane proteins and whole-cell heat-killed antigens in sera of patients with brucellosis.  

UK PubMed Central (United Kingdom)

An enzyme-linked immunosorbent assay was used to compare Brucella melitensis major outer membrane proteins (MOMP) and whole-cell heat-killed antigens (HK) in measuring antibrucella immunoglobulin G...Full Text Available

1989-08-01

224

DNA adducts in peripheral blood lymphocytes from aluminum production plant workers determined by 32P-postlabeling and enzyme-linked immunosorbent assay.  

UK PubMed Central (United Kingdom)

32P-Postlabeling analysis and enzyme-linked immunosorbent assay (ELISA) have been used to detect DNA adducts in peripheral blood lymphocytes from primary aluminum production plant workers who were exposed...Full Text Available

1993-03-01

225

Comparison of indirect immunofluorescent-antibody assay, enzyme-linked immunosorbent assay, and Western immunoblot for the diagnosis of Lyme disease in dogs.  

UK PubMed Central (United Kingdom)

Enzyme-linked immunosorbent assay (ELISA), indirect immunofluorescent-antibody assay (IFA), and Western immunoblot were used to test serum samples from 128 dogs for the presence of antibody to Borrelia...Full Text Available

1990-01-01

226

Comparative analysis of the ATRX promoter and 5' regulatory region reveals conserved regulatory elements which are linked to roles in neurodevelopment, alpha-globin regulation and testicular function  

UK PubMed Central (United Kingdom)

BackgroundATRX is a tightly-regulated multifunctional protein with crucial roles in mammalian development. Mutations in the ATRX gene cause ATR-X syndrome, an X-linked...Full Text Available

227

Characterization of Auxin Conjugates in Arabidopsis. Low Steady-State Levels of Indole-3-Acetyl-Aspartate, Indole-3-Acetyl-Glutamate, and Indole-3-Acetyl-Glucose1  

UK PubMed Central (United Kingdom)

Amide-linked indole-3-acetic acid (IAA) conjugates constitute approximately 90% of the IAA pool in the dicot Arabidopsis, whereas ester-linked conjugates and free IAA account for approximately...Full Text Available

2000-06-01

228

Analysis of a manipulator in relation to collision between a link and an object  

British Library Electronic Table of Contents (United Kingdom)

In this article, equations of motion of a manipulator are derived after consideration of the characteristics of the driving source. By considering a collision between a link and an object, and considering the active motion to absorb the kinetic energy of the object, the trajectories for saving energy are calculated by the iterative dynamic programming (IDP) method. The dynamic characteristics of manipulator control based on the trajectory for saving energy are also analyzed theoretically and investigated experimentally.

2011-01-01

229

A legal-historical consideration of links between Canadian and South African racial policies  

British Library Electronic Table of Contents (United Kingdom)

Significant recent writings have suggested strong parallels and actual links between the historical legal architectures of Canadian Aboriginal policy and South African apartheid. This article's further probing of these claims shows them to be very doubtful. At the same time, some more limited legal parallels between the two systems shows the importance of undertaking further analysis of the transmission and exchange of legal ideas and norms within the Commonwealth order.

2010-01-01

230

PSDE/SAT-2: Communication system architecture study, executive summary  

Science.gov (United States)

The PSDE/SAT-2 multimission satellite designed to offer a flight opportunity to different experimental communication payloads and verify the feasibility of advanced space technologies is described. It was conceived for expriment in the framework of the European DRS (Data Relay Satellite) program thus providing intersatellite and interorbit communication links, but also experimental and preoperative services. Payloads include optical communication single access payload (LSA); S-Band single access payload; S-Band multiple access payload; land mobile experimental payload; navigation payload; 40/50 GHz communication payload; and millimeter wave propagation payload. The orbital slot and interference analysis identified a limited number of orbital positions for the mission interleaved between Eutelsat satellites (i.e., 14 deg 30 min E and 17 deg 30 min E). A coordination is required in Ku-Band with Eutelsat satellites and in Ka-Band with ITALSAT (Italy) and TOR-12 (USSR) ...

1988-01-01

231

The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors  

UK PubMed Central (United Kingdom)

A hallmark of several human cancers is loss of heterozygosity (LOH) of chromosome 17p13. The same chromosomal region is also frequently hypermethylated in cancer. Although loss of 17p13 has been often...Full Text Available

232

Synthesis and properties of N,N-dialkyl-P-phenylphosphonamidous iodides  

Energy Technology Data Exchange (ETDEWEB)

N,N-Dialkyl-P-phenylphosphonamidous iodides are formed in the reactions of phenylphosphonus diiodide with silylated secondary amines. N,N-Dialkyl-P-phenylphosphonamidous iodides react with electrophilic reagents (methyl iodide, benzenesulfonyl azide, and phenyl azide) by the usual schemes with the formation of alkylation and oxidative-imination products. Iodine catalyzes the disproportionation of morpholinophenylphosphinous iodide into dimorphomorpholinophenylphosphinous iodide with iodine are iododimorpholinophenylphosphonium triiodide and phenylphosphonous diiodide.

1987-01-20

233

Statistical mapping analysis of serotonin synthesis images generated in healthy volunteers using positron-emission tomography and alpha-[11C]methyl-L-tryptophan.  

UK PubMed Central (United Kingdom)

OBJECTIVES: To assess the suitability of analyzing functional images of brain serotonin (5-HT) synthesis with statistical parametric mapping (SPM), and to investigate further possible sex-related regional...Full Text Available

2000-09-01

234

Relationship between O6-alkylguanine-DNA alkyltransferase activity and N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation, transformation, and cytotoxicity in C3H/10T1/2 cells expressing exogenous alkyltransferase genes.  

UK PubMed Central (United Kingdom)

While a great deal of evidence has directly implicated the importance of O6-alkylation of guanine in the mutagenicity of alkylating agents, evidence demonstrating the oncogenic potential of this lesion...Full Text Available

1992-12-01

235

Preparation and radiolabeling of IBZM: a potential D-2 specific brain imaging agents for SPECT  

International Nuclear Information System (INIS)

In developing new receptor-site specific brain imaging agents labeled with I-123 for single photon emission computed tomography (SPECT), an analog of raclopride, 3-["1"2"5I]-iodo-N-[(1-ethyl-2-pyrrolidinyl)-methyl]-2-hydroxy-6-me-thoxy benzamide (IBZM), was prepared using a method similar to that reported for raclopride and its derivatives. (author).

236

NMR study of aluminium chloride and lithium tetrachloroaluminate solutions in a mixed solvent of thionylchloride-methylacetate  

International Nuclear Information System (INIS)

Lithium tetrachloroaluminate solutions in thionylchloride, methylacetate and their mixtures are studied by "7Li and "2"7Al NMR. It is found that introduction of methylacetate in the LiAlCl_4-SOCl_2 system results in a change of lithium tetrachloroaluminate formation constant. In the ternary system, Li"+ is solvated by methyl-acetate after complete destruction of tetrachloroaluminate anion. Refs. 9, figs. 2.

237

Methylation similarities of two CpG sites within exon 5 of human H19 between normal tissues and testicular germ cell tumours of adolescents and adults, without correlation with allelic and total level of expression.  

UK PubMed Central (United Kingdom)

Testicular germ cell tumours (TGCTs) of adolescents and adults morphologically mimic different stages of embryogenesis. Established cell lines of these cancers are used as informative models to study...Full Text Available

1997-01-01

238

Methanol, MTBE suppliers will likely keep up with rising demand  

Energy Technology Data Exchange (ETDEWEB)

A primary and basic question prevails in the methanol industry - What will be the global demand for methanol, for the expanded production of methyl tertiary butyl ether (MTBE), during the next few years This article attempts to answer the question by discussing the global market; supply and demand factors; the market in North America, Western Europe, Far East and Asia, South America, and other regions; and the uncertainties that remain.

1993-03-29

239

Effects of alpha-deuterium substitution on the mutagenicity of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)  

Energy Technology Data Exchange (ETDEWEB)

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a carcinogenic tobacco specific nitrosamine, can be converted to electrophilic diazohydroxide intermediates by metabolic hydroxylation of either the methylene carbon (carbon 4) or the methyl carbon attached to the nitrosamine group. To investigate the relative importance of these two processes in NNK mutagenesis, we synthesized 4,4-dideutero-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone((4,4,-D2)NNK) and 4-(trideuteromethylnitrosamino)-1-(3-pyridyl)-1-butanone ((CD3) NNK), and evaluated their mutagenic activities in Salmonella typhimurium tester strains. In the presence of Aroclor induced rat liver 9000 g supernatant, NNK and (4,4-D2)NNK had comparable mutagenic activities towards S. typhimurium TA 1535 and TA 100, but (CD3)NNK was inactive in both strains. These results suggest that hydroxylation of the methyl group of NNK is more important than hydroxylation of carbon 4 in its activation ...

1983-01-01

240

Detection of acute myocardial infarction in spontaneously hypertensive rats by /sup 99m/Tc-Pyrrolidino methyl tetracycline  

Energy Technology Data Exchange (ETDEWEB)

The myocardial infarct induced by isoproterenol in spontaneously hypertensive rats accumulates higher activities of /sup 99/sup(m)Tc-PM tetracycline compared with the cardiac infarct in normotensive rats caused by the same method. The isoproterenol model of the myocardial necrosis was induced in intact rats without opening the thorax and is a convenient method for experimental radioisotope studies.

1983-01-01

241

Coulomb Repulsion in Miniature Ion Mobility Spectrometry  

Energy Technology Data Exchange (ETDEWEB)

We have undertaken a study of ion mobility resolution in a miniature ion mobility spectrometer with a drift channel 1.7 mm in diameter and 35 mm in length. The device attained a maximum resolution of 14 in separating ions of NO, O{sub 2}, and methyl iodine. The ions were generated by pulses from a frequency-quadrupled Nd:YAG laser. Broadening due to Coulomb repulsion was modeled theoretically and shown experimentally to have a major effect on the resolution of the miniature device.

1999-08-08

242

Control of pyrethroid and DDT-resistant Anopheles gambiae by application of indoor residual spraying or mosquito nets treated with a long-lasting organophosphate insecticide, chlorpyrifos-methyl  

UK PubMed Central (United Kingdom)

BackgroundScaling up of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) with support from the Global Fund and President's Malaria Initiative is providing...Full Text Available

243

Characterization and properties of monoammine nitroimidazole complexes of platinum (PtCl sub 2 (NH sub 3 )(NO sub 2 Im)). Crystal and molecular structure of cis-Amminedichloro(1-((((2-hydroxyethyl)amino)carbonyl)methyl)-2-nitroimidazole)platinum(II)  

Energy Technology Data Exchange (ETDEWEB)

The characterization of monoammine(nitroimidazole)platinum(II) complexes of structure (PtCl{sub 2}(NH{sub 3})(NO{sub 2}Im)) (NO{sub 2}Im = 1-((((2-hydroxyethyl)amino)carbonyl)methyl)-2-nitroimidazole, Etanidazole (I), 1-(2-nitro-1-imidazolyl)-3-methoxy2-propanol, Misonidazole (II), and 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole, Metronidazole (III)) is reported. Both is cis and trans isomers may be isolated for II and III. The crystal structure of cis-amminedichloro(1-((((2-hydroxyethyl)amino)carbonyl)methyl)-2-nitroimidazole)platinum(II) has been determined by X-ray diffraction. The crystals are orthorhombic, space group Pnab with cell dimensions a = 14.867 (7) {angstrom}, b = 9.915 (5) {angstrom}, c = 19.015 (9) {angstrom}, and Z = 8. The structure was refined to R = 0.062 and R{sub w} = 0.052. Platinum has the expected square-planar coordination. The Pt-Cl bond trans to the nitroimidazole ligand is shorter (2.269 (3) ...

1991-11-27

244

A Facile One-Pot Expeditious Synthesis of Thiazolyl-pyrazolones  

British Library Electronic Table of Contents (United Kingdom)

A novel, one-pot, multicomponent synthesis of 4-arylidene-3-methyl-1-(4-arylthiazol-2-yl)-1H-pyrazol-5(4H)-ones is described using phenacyl bromides, thiosemicarbazide, ethylacetoacetate, and aryl aldehydes. This synthesis involves simultaneous formation of two heterocycles like thiazole and pyrazolone along with condensation of active methylene group by aldehydes via Knoevenagel reaction. The methodology is mild, efficient, and high yielding. GRAPHICAL ABSTRACT[image omitted

2011-01-01

245

Gas and stellar dynamics in NGC 1068. Probing the galactic gravitational potential  

CERN Document Server

We present Sauron 2D spectrography of the central 1.5 kpc of the nearby Sey2 galaxy NGC1068, encompassing the well-known NIR inner bar. We have successively disentangled the respective contributions of the ionized gas and stars, thus deriving their 2D distribution and kinematics. The [OIII] and Hbeta emission lines exhibit very different spatial distribution and kinematics, the latter following inner spiral arms with clumps associated with star formation. Strong inwards streaming motions are observed in both the Hbeta and [OIII] kinematics. The stellar kinematics also exhibit clear signatures of a non-axisymmetric tumbling potential, with a twist in both the velocity and h3 fields. We re-examined the long-slit data of Shapiro et al (2003) using pPXF: a strong decoupling of h3 is revealed, and the central decrease in h4 hinted in the Sauron data is confirmed. These data also suggest that NGC1068 is a ...

2006-01-01

246

Direct solar water splitting cell using water, WO3, Pt, and polymer electrolyte membrane  

British Library Electronic Table of Contents (United Kingdom)

A solar water splitting cell composed of WO3, Polymer Electrolyte Membrane (PEM) and Pt was constructed for producing hydrogen from deionized water in sunlight. Spectral responsivity measurements under various temperatures and bias voltages were conducted for the cell using the Incident Photon to Current Efficiency (IPCE) method. For comparison, a known WO3 Photo Electro Chemical (PEC) cell containing H3PO4 electrolyte, WO3/H3PO4/Pt, was tested using the same test method. The WO3/PEM-H2O/Pt cell showed better Quantum Efficiency (QE) performance compared to that obtained from the cell with the chemical electrolyte. For the first time, spectral responsivity of photo water splitting process without bias power was unveiled in the new WO3 cell, demonstrating the self-sustained photo electrolysi...

2009-01-01

247

Extraction of magnesium as the iodide by tributyl phosphate  

Science.gov (United States)

The extraction of magnesium by tributyl phosphate from KI solutions was investigated. With increasing KI and TBP concentrations, the extraction increased. The maximum extraction (82%) was attained at pH 4, and it did not decrease with a further pH increase. With decreasing pH, the extraction decreased because of HI extraction. The magnesium was extracted as the compound MgI/sub 2/ x 4TBP. Complexone III (at pH 3-4) does not affect the extraction of magnesium, which makes it possible to use it to mask other metals.

1987-08-20

248

Effect of pH on the pitting corrosion of austenitic stainless steel in chloride solution  

International Nuclear Information System (INIS)

This paper deals with the pitting corrosion of evaporators in the liquid - radwaste system of nuclear power stations. Corrosion testrs were conducted by the anodic polalization of specimen in the chloride solution. (1) The initiation of the pitting in SUS 304, SUS 316 stainless steels was inhibited by addition of NaOH and H_3BO_3, however, these addition had no effect on the pitting propagation. (2) Inconel 625 had the resitivity against the pitting initiation superior to that of stainless steels, but this was not necessarily in the case of the pitting propagation. (3) It is noticed for pitting prevention that the environmental and material effect on the pitting initiation differed from that on the pitting propagation. (author).

249

High-precision Penning-Trap measurements of light-ion masses  

International Nuclear Information System (INIS)

The UW-Penning Trap Mass Spectrometer (PTMs) is ideally suited for high precision measurements of atomic masses throughout the periodic table upon using highly-stripped ions. However, at the present time, this device has been applied extensively to the light elements ("1H, "2H, "3H, "3He, "4He, "1"2C, "1"3C, "1"4N, "1"6O) due to their fundamental importance. Atomic masses follow immediately from a comparison with some multiply-charged carbon ion, after correcting for the lost electrons and their corresponding binding energies. For instance, the most recent C"5"+/C"6"+ comparison yielded a discrepancy of -0.30(33) ppb, limited only by the magnetic field instability for a 40-h run. The initial emphasis on hydrogen has now produced a 1-ppb value for the proton's atomic mass and similar work with deuterium has yielded a 2.5-ppb value for the neutron's atomic mass. However, the most significant result is the ...

1993-04-12

250

Adsorption and dissociation of water on the (0001) surface of double hexagonal close packed americium  

International Nuclear Information System (INIS)

Ab initio total energy calculations within the framework of density functional theory have been performed for water molecule adsorption on the (0001) surface of double hexagonal packed americium using a full-potential all-electron linearized augmented plane wave plus local orbitals method (FP-L/APW+lo). Subsequent partial dissociation (OH+H) and complete dissociation (H+O+H) of the water molecule have been examined. The completely dissociated H+O+H configuration exhibit the strongest binding with the surface (3.35 eV), followed by partially dissociated species OH+H (2.23 eV), with all molecular H_2O configurations showing weak physisorption (0.366 eV). For molecular adsorptions, the flat lying orientation of the water molecule if found to be more favorable for majority of the cases. In the case of partial dissociation (OH+H), the vertical orientation of OH molecule with O facing the surface adsorbed at a h3 adsorption site and the H atom ...

2009-06-01

251

Magnetic resonance imaging of stents. Quantitative in vitro examination at 3 Tesla; Magnetresonanztomographie von Stents. Quantitative MR-Untersuchungen in vitro bei 3 Tesla  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study was to qualitatively and quantitatively study MR artifacts of various stents on the basis of in vitro experiments. We were particularly interested whether sequence type and orientation of the stent with respect to the static magnetic field influences the artifact. We examined 18 stents of different material (nitinol, stainless steel, cobalt alloy), different design of the stent meshes (AccuLink, OmniLink, DynaLink, Xact, Protoge, Wallstent Monorail), different diameter (5-10 mm) and different length (18-58 mm) with a turbo spin echo (TSE), a 2D-fast low angle shot (FLASH) and a 3D-FLASH sequence. The MR images were examined qualitatively with respect to possible artifacts. Furthermore we examined the MR data quantitatively: The contrast-noise-ratio (CNR) was determined both within the stent and outside (within the tube); based on these values we calculated the transparency factor P, furthermore we ...

2009-07-01

252

Understanding Japanese society through life after death  

British Library Electronic Table of Contents (United Kingdom)

In this article based on extensive ethnographic interviewing of eighty-six Japanese adults, I analyze the different ways in which they understand life after death, and consider the societal implications of their views. I examine senses of life after death as based in communion with departed family members as linked to practices of ancestor veneration and ideologies of Japaneseness. I consider heaven/hell or reincarnation as linked, through the idea of impartial judgment of the individual, to meritocracy and the examination system. I examine agnosticism and relativism in senses of life after death as linked to the idea that individual freedom of choice may exist in the next world if not necessarily within the constraints of this Japanese world. I examine disbelief in any realm beyond the gr...

2011-01-01

253

solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database  

UK PubMed Central (United Kingdom)

BackgroundA common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs requires...Full Text Available

254

Zn, Cu, Cd and Hg binding to metallothioneins in harbour porpoises Phocoena phocoena from the southern North Sea  

UK PubMed Central (United Kingdom)

BackgroundHarbour porpoises Phocoena phocoena from the southern North Sea are known to display high levels of Zn and Hg in their tissues linked to their nutritional...Full Text Available

255

Wnt3a Induces Myofibroblast Differentiation by Upregulating TGF-? Signaling Through SMAD2 in a ?-Catenin-Dependent Manner  

UK PubMed Central (United Kingdom)

Growing evidence suggests the Wnt family of secreted glycoproteins and their associated signaling pathways, linked to development, are recapitulated during wound repair and regeneration events. However,...Full Text Available

256

Variation in Nicotine Consumption in Inbred Mice Is Not Linked to Orosensory Ability  

UK PubMed Central (United Kingdom)

Genetic studies of nicotine addiction in mice have utilized the oral self-administration model. However, it is unclear if strain differences in nicotine consumption are influenced by variation in bitter...Full Text Available

2009-01-01

257

Use of Dimethyl Suberimidate, a Cross-Linking Reagent, in Studying the Subunit Structure of Oligomeric Proteins*  

UK PubMed Central (United Kingdom)

Amidination of aldolase, glyceraldehyde-3-phosphate dehydrogenase, tryptophan synthetase B protein, L-arabinose isomerase, and the catalytic subunit of E. coli aspartate transcarbamylase...Full Text Available

1970-07-01

258

Untreated Poor Vision: A Contributing Factor to Late-Life Dementia  

UK PubMed Central (United Kingdom)

Ophthalmologic abnormalities have been described in patients with dementia, but the extent to which poor vision and treatment for visual disorders affect cognitive decline is not well defined. Linked...Full Text Available

2010-03-15

259

Uneven dietary development: linking the policies and processes of globalization with the nutrition transition, obesity and diet-related chronic diseases  

UK PubMed Central (United Kingdom)

In a "nutrition transition", the consumption of foods high in fats and sweeteners is increasing throughout the developing world. The transition, implicated in the rapid rise of obesity and diet-related...Full Text Available

260

Underground cable: Best for cogeneration links  

Energy Technology Data Exchange (ETDEWEB)

This article addresses the connection of cogeneration plants to the utility system. The article provides examples for use in illustrating the problems that must be overcome and the solution chosen. These illustrations include high voltage utility connection, multiple connections to the utility at one location, and dealing with losses and obstructions.

1989-05-01

261

Two-site exchange revisited: a new method for extracting exchange parameters in biological systems.  

UK PubMed Central (United Kingdom)

A new analysis is presented which links real volume fractions, relaxation rates, and intracompartmental exchange rates directly with apparent volume fractions and relaxation rates obtained from biexponential...Full Text Available

1989-02-01

262

Two tandemly linked identical genes code for the glycosomal glyceraldehyde-phosphate dehydrogenase in Trypanosoma brucei.  

UK PubMed Central (United Kingdom)

Trypanosoma brucei contains two isoenzymes for glyceraldehyde-phosphate dehydrogenase (GAPDH); one enzyme resides in a microbody-like organelle, the glycosome, the other one is found in the cytosol....Full Text Available

1986-05-01

263

Tumor-Endothelial Interaction Links the CD44+/CD24- Phenotype with Poor Prognosis in Early-Stage Breast Cancer1  

UK PubMed Central (United Kingdom)

Materials and MethodsThe genomic effects of tumor-endothelial interactions in cancer are not yet well characterized. To study this interaction in breast...Full Text Available

2009-10-01

264

Trends in use of opioids for chronic non-cancer pain among individuals with mental health and substance use disorders: the TROUP study  

UK PubMed Central (United Kingdom)

ObjectivesUse of prescription opioids for chronic pain is increasing, as is abuse of these medications, though the nature of the link between these trends is unclear....Full Text Available

2010-01-01

265

Thermodynamic and structural analysis of microtubule assembly: the role of GTP hydrolysis.  

UK PubMed Central (United Kingdom)

Different models have been proposed that link the tubulin heterodimer nucleotide content and the role of GTP hydrolysis with microtubule assembly and dynamics. Here we compare the thermodynamics of...Full Text Available

1997-03-01

266

The selection and definition of targeted work-related conditions for surveillance under SENSOR.  

UK PubMed Central (United Kingdom)

Lists of reportable conditions and case definitions are important tools for epidemiologic surveillance. As part of an initiative to encourage occupational disease surveillance systems linked to intervention...Full Text Available

1989-12-01

267

The red-green visual pigment gene region in adrenoleukodystrophy.  

UK PubMed Central (United Kingdom)

Although recent data established that a specific very-long-chain fatty acyl-CoA synthetase is defective in X-linked adrenoleukodystrophy (ALD), the ALD gene is still unidentified. The ALD locus has...Full Text Available

1990-03-01

268

The Induction of APC with a Distinct Tolerogenic Phenotype via Contact-Dependent STAT3 Activation  

UK PubMed Central (United Kingdom)

BackgroundActivation of the signal transducer and activator of transcription 3 (STAT3) within antigen presenting cells (APCs) is linked to abnormal APCs differentiation and function....Full Text Available

269

The GLAST Science Support Center - NASA  

Science.gov (United States)

~4-5 times per day through a 40 Mbps Ku-band TDRSS link, while commands are uplinked on a 4 ..... During Phase 2 the budget will be ~$6M/year. Accounting ...

270

Temporal changes in key maternal and fetal factors affecting birth outcomes: A 32-year population-based study in an industrial city  

UK PubMed Central (United Kingdom)

BackgroundThe link between maternal factors and birth outcomes is well established. Substantial changes in society and medical care over time have influenced women's reproductive...Full Text Available

271

TABLE A: SPTR SITE SELECTION ANALYSIS LOCATION V ... - NASA  

Science.gov (United States)

OPERATE AT SOUTH POLE WINTER AMBIENTS, GIVEN THE PROJECT'S BUDGET AND TIME LINES . ... 17 MAXIMUM ELECTRICAL LENGHT CONSTRAINED BY Ku-BAND AT 50 FT. ... A MAXIMUM LENGTH OF 50 FEET HAS BEEN SPECIFIED BY THE SYSTEM LINK CALCULATIONS TO ...

272

System Design and Applications of the Ultra Small ... - GLTRS - NASA  

Science.gov (United States)

The advanced technologies of Ka-Band systems such as high gain spot .... sometimes used based on link requirements for a specific application. .... received at NASA LeRC from a Ku-band satellite and retransmitted to the USAT at Ka-Band. .... and to the Office of Management and Budget, Paperwork Reduction Project ...

273

Stress Resistance and Longevity Are Not Directly Linked to Levels of Enzymatic Antioxidants in the Ponerine Ant Harpegnathos saltator  

UK PubMed Central (United Kingdom)

BackgroundThe molecular mechanisms of variations in individual longevity are not well understood, even though longevity can be increased substantially by means of diverse experimental...Full Text Available

274

Social media - Social media, The University of York  

Wastenet

...A directory of University social media accounts, including Facebook, Twitter and YouTube facebook, twitter, blog Social media - Social media, The ... Key: Facebook, Twitter, YouTube, Blog, LinkedIn, Flickr Missed you out? If you'd like to be included on this ...

275

Seasonal streamflow forecast: a GCM multi-model downscaling approach on Environmental Expert  

Wastenet

...Seasonal streamflow forecast: a GCM multi-model downscaling approach on Environmental Expert Bulletins Environmental Expert RSS Environmental Expert facebook Environmental Expert twitter Environmental Expert LinkedIn ...

276

Robust consensus clustering for identification of expressed genes linked to malignancy of human colorectal carcinoma  

UK PubMed Central (United Kingdom)

Previous studies have been conducted in gene expression profiling to identify groups of genes that characterize the colorectal carcinoma disease. Despite the success of previous attempts to identify...Full Text Available

277

Reproductive factors and risks of biliary tract cancers and stones: a population-based study in Shanghai, China  

UK PubMed Central (United Kingdom)

Background:Parity has been linked to gallbladder cancer and gallstones, but the effects of other reproductive factors are less clear.Methods:We examined...Full Text Available

2010-03-30

278

Rapid in vivo transport and catabolism of human apolipoprotein A-IV-1 and slower catabolism of the apoA-IV-2 isoprotein.  

UK PubMed Central (United Kingdom)

Apolipoprotein (apo) A-IV is a polymorphic, intestinally derived apolipoprotein that is genetically linked to and similar in structure to apoA-I, the major apolipoprotein in high density lipoproteins...Full Text Available

1993-08-01

279

Rainforest Portal Rainforest Conservation Links: Information/Maps  

Wastenet

... 12, 2007 | Rate It Distribution and Variety of Equatorial Rain Forest , The http://www.esd.ornl.gov/projects/qen/rainfo.html (3 votes) an in depth examination of ecological patterns in rainforests from the Oak Ridge National Laboratory Added: Mar. 17, 2001 ...

280

Quantitative and Qualitative Usage Data of an Internet-Based Asthma Monitoring Tool  

UK PubMed Central (United Kingdom)

Background In May 2000, AstraZeneca launched a Web service for asthma patients and health-care providers called LinkMedica, which includes an asthma diary for...Full Text Available

281

Physical Activity and Telomere Biology: Exploring the Link with Aging-Related Disease Prevention  

UK PubMed Central (United Kingdom)

Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans. Though these associations are well established, evidence...Full Text Available

282

Persistence of Free-Living Protozoan Communities across Rearing Cycles in Commercial Poultry Houses ?  

UK PubMed Central (United Kingdom)

The introduction and survival of zoonotic bacterial pathogens in poultry farming have been linked to bacterial association with free-living protozoa. To date, however, no information is available on...Full Text Available

2011-03-01

283

Perceived association between diagnostic and non-diagnostic cues of women's sexual interest: General Recognition Theory predictors of risk for sexual coercion  

UK PubMed Central (United Kingdom)

Young men's errors in sexual perception have been linked to sexual coercion. The current investigation sought to explicate the perceptual and decisional sources of these social perception errors,...Full Text Available

2010-01-01

284

Palindromic Sequence Plays a Critical Role in Human Foamy Virus Dimerization  

UK PubMed Central (United Kingdom)

The retroviral RNA genome is dimeric, consisting of two identical strands of RNA linked near their 5′ ends by a dimer linkage structure. Previously it was shown that human foamy virus (HFV)...Full Text Available

2001-04-01

285

PDP-1 Links the TGF-? and IIS Pathways to Regulate Longevity, Development, and Metabolism  

UK PubMed Central (United Kingdom)

The insulin/IGF-1 signaling (IIS) pathway is a conserved regulator of longevity, development, and metabolism. In Caenorhabditis elegans IIS involves activation of DAF-2 (insulin/IGF-1...Full Text Available

2011-04-01

286

Oxidative Stress and Longevity in Okinawa: An Investigation of Blood Lipid Peroxidation and Tocopherol in Okinawan Centenarians  

UK PubMed Central (United Kingdom)

Background. The Free Radical Theory of Aging mechanistically links oxidative stress to aging. Okinawa has among the world's longest-lived populations but oxidative stress in this...Full Text Available

2010-01-01

287

OF 2004-1095: Results of Electrical Resistivity Data Collected...  

Science.gov (United States)

Link to USGS home page Results of Electrical Resistivity Data Collected near the Town of Guernsey, Platte County, Wyoming By Robert R. McDougal, Jared D. Abraham, and Robert J....

2011-08-20

288

Nonlinear time-periodic models of the longitudinal flight dynamics of desert locusts Schistocerca gregaria  

UK PubMed Central (United Kingdom)

Previous studies of insect flight control have been statistical in approach, simply correlating wing kinematics with body kinematics or force production. Kinematics and forces are linked by Newtonian...Full Text Available

2005-06-22

289

Nonlinear response of superconductors to alternating fields and currents  

Science.gov (United States)

This report discusses the following topics on superconductivity: nonlinearities in hard superconductors such as surface impedance of a type II superconductimg half space and harmonic generation and intermodulation due to alternating transport currents; and nonlinearities in superconducting weak links such as harmonic generation by a long Josephson Junction in a superconducting slab.

1997-10-08

290

Neural injury following stroke: are Toll-like receptors the link between the immune system and the CNS?  

UK PubMed Central (United Kingdom)

The CNS can exhibit features of inflammation in response to injury, infection or disease, whereby resident cells generate inflammatory mediators, including cytokines, prostaglandins, free radicals and...Full Text Available

2010-08-01

291

Network information security in a phase III Integrated Academic Information Management System (IAIMS).  

UK PubMed Central (United Kingdom)

The developing Integrated Academic Information System (IAIMS) at Columbia-Presbyterian Medical Center provides data sharing links between two separate corporate entities, namely Columbia University...Full Text Available

1992-01-01

292

NAME=\\  

Wastenet

...links ensure all of our managed accommodation is easily accessible to both campus sites and our special student arrangement makes travelling on the Metro rapid transit system easily affordable. Our halls are comfortable and they are very reasonable. Download the rents table here Rents 2009-2010 Students living in ...

293

Myelin associated glycoprotein cross-linking triggers its partitioning into lipid rafts, specific signaling events and cytoskeletal rearrangements in oligodendrocytes  

UK PubMed Central (United Kingdom)

Myelin-associated glycoprotein (MAG) has been implicated in inhibition of nerve regeneration in the CNS. This results from interactions between MAG and the Nogo receptor and gangliosides on...Full Text Available

2004-02-01

294

Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila  

UK PubMed Central (United Kingdom)

Neuroblasts in the developing Drosophila CNS asymmetrically localize the cell fate determinants Numb and Prospero as well as prospero RNA to the basal cortex during...Full Text Available

1998-06-15

295

Microglial Fc Receptors Mediate Physiological Changes Resulting From Antibody Cross-Linking of Myelin Oligodendrocyte Glycoprotein  

UK PubMed Central (United Kingdom)

Antibodies to myelin oligodendrocyte glycoprotein (MOG) have been implicated in Multiple Sclerosis demyelination through activation of complement and/or macrophage-effector processes. We presented...Full Text Available

2008-05-30

296

Metabolism of the benzidine-based azo dye Direct Black 38 by human intestinal microbiota.  

UK PubMed Central (United Kingdom)

Benzidine-based azo dyes are proven mutagens and have been linked to bladder cancer. Previous studies have indicated that their initial reduction is the result of the azo reductase activity of the intestinal...Full Text Available

1985-07-01

297

Marine Geology and Earthquake Hazards of the San Pedro Shelf...  

Science.gov (United States)

125 Years of Science for America - 1879 to 2004 link to Western Coastal and Marine Geology website U.S. Geological Survey Professional Paper 1687 Marine Geology and Earthquake...

2011-08-20

298

Mapping Drug Physico-Chemical Features to Pathway Activity Reveals Molecular Networks Linked to Toxicity Outcome  

UK PubMed Central (United Kingdom)

The identification of predictive biomarkers is at the core of modern toxicology. So far, a number of approaches have been proposed. These rely on statistical inference of toxicity response from either...Full Text Available

299

Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance  

UK PubMed Central (United Kingdom)

Obesity and metabolic syndrome result from excess calorie intake and genetic predisposition and are mechanistically linked to type II diabetes and accelerated body aging; abnormal nutrient and insulin...Full Text Available

2010-07-27

300

Linking global warming to amphibian declines through its effects on female body condition and survivorship (PDF, 7 pp., ...  

Science.gov (United States)

There is general consensus that climate change has contributed to the observed decline, and extinction, of many amphibian species throughout the world. ... ...

301

Linking Gene Expression and Functional Network Data in Human Heart Failure  

UK PubMed Central (United Kingdom)

BackgroundGene expression profiling and the analysis of protein-protein interaction (PPI) networks may support the identification of disease bio-markers and potential drug targets....Full Text Available

302

Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies  

UK PubMed Central (United Kingdom)

Recently, genome-wide association studies (GWAS) have linked the human LIN28B locus to height and timing of menarche [1-Full Text Available

2010-07-01

303

Interaction between various polymerized human albumins and hepatitis B surface antigen.  

UK PubMed Central (United Kingdom)

A variety of albumin polymers were prepared and tested for binding with hepatitis B surface antigen (HBsAg): synthetic polymers cross-linked by either glutaraldehyde or carbodiimide; heat-aggregated...Full Text Available

1985-09-01

304

Influence of invertase activity and glycerol synthesis and retention on fermentation of media with a high sugar concentration by Saccharomyces cerevisiae.  

UK PubMed Central (United Kingdom)

In the past, the fermentation activity of Saccharomyces cerevisiae in substrates with a high concentration of sucrose (HSuc), such as sweet bread doughs, has been linked inversely to invertase activity...Full Text Available

1997-01-01

305

In vivo cartilage contact strains in patients with lateral ankle instability  

UK PubMed Central (United Kingdom)

Damage to the anterior talofibular ligament (ATFL) and cacaneofibular ligament (CFL) during ankle sprain may be linked to the development of osteoarthritis. Altered tibiotalar kinematics have...Full Text Available

2010-09-17

306

In vitro studies on the adjuvanticity of Brucella fractions.  

UK PubMed Central (United Kingdom)

Two Brucella fractions, the murein-linked fraction PI and the murein-free fraction SF, behave as in vitro adjuvants for primary anti-sheep erythrocyte responses: added to Mishell and Dutton-type cultures...Full Text Available

1982-11-01

307

In Vivo Reconstitution of ?-Secretase in Drosophila Results in Substrate Specificity?  

UK PubMed Central (United Kingdom)

The intramembrane aspartyl protease γ-secretase plays a fundamental role in several signaling pathways involved in cellular differentiation and has been linked with a variety of human diseases,...Full Text Available

2010-07-01

308

Imaging Alzheimer Pathology in Late-Life Depression With PET and Pittsburgh Compound-B  

UK PubMed Central (United Kingdom)

There is increasing evidence for an empiric link between late-life depression and Alzheimer disease (AD). The neuropathology of AD, previously only confirmed at autopsy, may now be detectable...Full Text Available

2008-01-01

309

Ichthyosis follicularis, alopecia, and photophobia (IFAP) syndrome  

UK PubMed Central (United Kingdom)

The IFAP syndrome is a rare X-linked genetic disorder reported in nearly 40 patients. It is characterized by the triad of Ichthyosis Follicularis, Alopecia, and Photophobia from birth. Other features...Full Text Available

310

Hepatitis B virus infection and primary hepatocellular carcinoma.  

UK PubMed Central (United Kingdom)

For many years, epidemiological studies have demonstrated a strong link between chronic hepatitis B virus (HBV) infection and the development of primary hepatocellular carcinoma (PHC). Other hepatocarcinogens...Full Text Available

1992-07-01

311

Geology of the Ocoee Whitewater Center, Cherokee National Forest  

Science.gov (United States)

World - USGS visual identity mark and link to main Web site at http://www.usgs.gov/ GEOLOGY OF THE OCOEE WHITEWATER CENTER, CHEROKEE NATIONAL FOREST Ocoee Whitewater Center logo...

2011-08-20

312

Genetic evidence of illegal trade in protected whales links Japan with the US and South Korea  

UK PubMed Central (United Kingdom)

We report on genetic identification of ‘whale meat’ purchased in sushi restaurants in Los Angeles, CA (USA) in October 2009 and in Seoul, South Korea in June and September 2009. Phylogenetic...Full Text Available

2010-10-23

313

G?i generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts  

UK PubMed Central (United Kingdom)

Drosophila neuroblasts divide asymmetrically by aligning their mitotic spindle with cortical cell polarity to generate distinct sibling cell types. Neuroblasts asymmetrically localize...Full Text Available

2007-09-04

314

Functional Enhancers at the Gene-Poor 8q24 Cancer-Linked Locus  

UK PubMed Central (United Kingdom)

Multiple discrete regions at 8q24 were recently shown to contain alleles that predispose to many cancers including prostate, breast, and colon. These regions are far from any annotated gene and their...Full Text Available

2009-08-01

315

Final report for the Pre-Freshman Enrichment Program (PREP)  

Energy Technology Data Exchange (ETDEWEB)

This project reflected cooperation across the disciplines in the physical sciences, engineering, mathematics and computer science. The University of the Pacific served as the center for this pre-college program. The idea was to use this link as a pilot program.

1998-03-01

316

FAQ: Earthquakes, Faults, Plate Tectonics, Earth Structure  

Science.gov (United States)

This frequently-asked-questions feature provides answers about earthquakes, faults, plate tectonics, and earth structure. Maps and diagrams are provided with some answers, and links to additional information and to related topics are included.

317

Exploding Bridgewire Electrical System Test Unit.  

Science.gov (United States)

The object of the test was to develop a method to field test the Exploding Bridgewire (EBW) System for proper functioning prior to use. Two basic designs were conceived and tested. The first design using a two element spark gap and a calibrated fuse link ...

1964-01-01

318

Evolution of DMY, a newly emergent male sex-determination gene of medaka fish.  

UK PubMed Central (United Kingdom)

The Japanese medaka fish Oryzias latipes has an XX/XY sex-determination system. The Y-linked sex-determination gene DMY is a duplicate of the autosomal gene DMRT1, which encodes a DM-domain-containing...Full Text Available

2004-04-01

319

Evidence of linkage disequilibrium in the Spanish polycystic kidney disease I population.  

UK PubMed Central (United Kingdom)

Forty-one Spanish families with polycystic kidney disease 1 (PKD1) were studied for evidence of linkage disequilibrium between the disease locus and six closely linked markers. Four of these loci--three...Full Text Available

1994-05-01

320

Evidence of an inflammatory-like response in non-normally pigmented tissues of two scleractinian corals  

UK PubMed Central (United Kingdom)

Increasing evidence of links between climate change, anthropogenic stress and coral disease underscores the importance of understanding the mechanisms by which reef-building corals resist infection...Full Text Available

2008-12-07

321

Evidence for increased in vitro recombination with insertion of human hepatitis B virus DNA.  

UK PubMed Central (United Kingdom)

Chromosomal translocation, deletion, and inversion/duplication directly linked to hepatitis B virus (HBV) DNA integration occur frequently in host DNA of human hepatocellular carcinomas. To test the...Full Text Available

1991-10-15

322

Estimating trace deposition time with circadian biomarkers: a prospective and versatile tool for crime scene reconstruction  

UK PubMed Central (United Kingdom)

Linking biological samples found at a crime scene with the actual crime event represents the most important aspect of forensic investigation, together with the identification of the sample donor. While...Full Text Available

2010-09-01

323

Engineering ligand-responsive RNA controllers in yeast through the assembly of RNase III tuning modules  

UK PubMed Central (United Kingdom)

The programming of cellular networks to achieve new biological functions depends on the development of genetic tools that link the presence of a molecular signal to gene-regulatory activity. Recently,...Full Text Available

2011-07-01

324

Elevated BMI Is Associated With Decreased Blood Flow in the Prefrontal Cortex Using SPECT Imaging in Healthy Adults  

UK PubMed Central (United Kingdom)

Obesity is a risk factor for stroke and neurodegenerative disease. Excess body fat has been linked to impaired glucose metabolism, insulin resistance, and impulsivity and may be a precursor to decline...Full Text Available

2011-05-01

325

Effects of a community mental health service on the practice and attitudes of general practitioners.  

UK PubMed Central (United Kingdom)

Recent years have seen closer links developing between general practitioners and mental health specialists. A study was undertaken in Manchester to determine the effects of a new community mental health...Full Text Available

1993-12-01

326

EcoEarth.Info Environment Links: Water/Rivers  

Wastenet

... 03, 2001 | Rate It Lake Superior Streams http://www.lakesuperiorstreams.org/ (1 vote) interactively examine real-time water quality data from 5 ...north shore Lake Superior trout streams and learn about other streams in the region, how they \\

327

Dynamic body weight and body composition changes in response to subordination stress  

UK PubMed Central (United Kingdom)

Social stress is prevalent in many facets of modern society. Epidemiological data suggest that stress is linked to the development of overweight, obesity and metabolic disease. Although there...Full Text Available

2007-07-24

328

Does It Matter What You Measure? Neighbourhood Effects in a Canadian Setting  

UK PubMed Central (United Kingdom)

Data from 8,032 Manitoba respondents to the 1996/97 Canadian National Population Health Survey were linked to the 1996 census to study whether measures of morbidity, both self-reported and objectively...Full Text Available

2010-08-01

329

Dirt Cheap and Without Prescription: How Susceptible are Young US Consumers to Purchasing Drugs From Rogue Internet Pharmacies?  

UK PubMed Central (United Kingdom)

BackgroundWebsites of many rogue sellers of medications are accessible through links in email spam messages or via web search engines. This study examined...Full Text Available

330

Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice  

UK PubMed Central (United Kingdom)

Uncoupling protein 2 (UCP2) maps to a region on distal mouse chromosome 7 that has been linked to the phenotypes of obesity and type II diabetes. We recently reported that UCP2 expression is increased...Full Text Available

1998-03-31

331

Detecting Retroviral Sequences in Chronic Fatigue Syndrome  

UK PubMed Central (United Kingdom)

XMRV or xenotropic murine leukemia virus-related retrovirus, a recently discovered retrovirus, has been linked to both prostate cancer and chronic fatigue syndrome (CFS). Recently, the teams of Drs....Full Text Available

332

Destructive effects of smoking on molecular and genetic factors of periodontal disease  

UK PubMed Central (United Kingdom)

Many epidemiological evidences have proven the association between smoking and periodontal disease. The causality can be further established by linking findings of traditional epidemiological studies...Full Text Available

333

Design of 240,000 orthogonal 25mer DNA barcode probes  

UK PubMed Central (United Kingdom)

DNA barcodes linked to genetic features greatly facilitate screening these features in pooled formats using microarray hybridization, and new tools are needed to design large sets of barcodes to allow...Full Text Available

2009-02-17

334

Depression and physical activity in a sample of nigerian adolescents: levels, relationships and predictors  

UK PubMed Central (United Kingdom)

BackgroundPhysical inactivity is related to many morbidities but the evidence of its link with depression in adolescents needs further investigation in view of the existing conflicting...Full Text Available

335

Deformed Wing Virus Implicated in Overwintering Honeybee Colony Losses ?  

UK PubMed Central (United Kingdom)

The worldwide decline in honeybee colonies during the past 50 years has often been linked to the spread of the parasitic mite Varroa destructor and its interaction with certain honeybee...Full Text Available

2009-11-01

336

DefenseLINK News: Fourth Haiti Contingency Exercise  

Science.gov (United States)

... exercise to Port Au Prince, Haiti, begins Friday, April 11, 1997, when a company-sized element from the Army's 82nd Airborne Division from Fort ...

337

Confusion after spine injury: cerebral fat embolism after traumatic rupture of a Tarlov cyst: Case report  

UK PubMed Central (United Kingdom)

BackgroundAcute low back pain is a very common symptom and reason for many medical consultations. In some unusual circumstances it could be linked to a rare aetiology.Case...Full Text Available

338

Comparison of Genotypes of Salmonella enterica Serovar Enteritidis Phage Type 30 and 9c Strains Isolated during Three Outbreaks Associated with Raw Almonds?  

UK PubMed Central (United Kingdom)

In 2000 to 2001, 2003 to 2004, and 2005 to 2006, three outbreaks of Salmonella enterica serovar Enteritidis were linked with the consumption of raw almonds. The S....Full Text Available

2010-06-01

339

Comparative Medicine - National Center for Research Resources...  

Science.gov (United States)

and Antibody Responses of Rhesus Macaques Exposed to the Human Gammaretrovirus XMRV external link, opens in new window J Virol. 2011 May;85(9):4547-57 Detection of CWD...

2011-10-15

340

Common Familial Colorectal Cancer Linked to Chromosome 7q31: a genome-wide analysis  

UK PubMed Central (United Kingdom)

Present investigations suggest that approximately 30% of colorectal cancer (CRC) cases arise on the basis of inherited factors. We hypothesize that the majority of inherited factors are moderately...Full Text Available

2008-11-01

341

Civil and Military Satellite Communications: A Systems ...  

Science.gov (United States)

... to-noise density than the uplink budget has (74.2 ... in heav:, point-to-point link applications with ... 11.7 Expanded bands allocated (Ku band) (500 MHz ...

1991-02-01

342

Chronic Fatigue: Can Natural Remedies Boost My Energy?  

Science.gov (United States)

... Question Chronic fatigue: Can natural remedies boost my energy? Are there any natural remedies that reduce chronic ... AN01764 ">Chronic fatigue: Can natural remedies boost my energy? Guidelines for sites linking to MayoClinic.com ...

343

Chemical complementation: A reaction-independent genetic assay for enzyme catalysis  

UK PubMed Central (United Kingdom)

A high-throughput assay for enzyme activity has been developed that is reaction independent. In this assay, a small-molecule yeast three-hybrid system is used to link enzyme catalysis to transcription...Full Text Available

2002-12-24

344

Cell resilience in species lifespans: a link to inflammation?  

UK PubMed Central (United Kingdom)

Species differences in lifespan have been attributed to cellular survival during various stressors, designated here as ‘cell resilience’. In primary fibroblast cultures, cell...Full Text Available

2010-08-01

345

Cancer Risk in Type 2 Diabetes Mellitus: Metabolic Links and Therapeutic Considerations  

UK PubMed Central (United Kingdom)

Type 2 diabetes mellitus (DM2) is increasing in incidence, creating worldwide public health concerns and impacting morbidity and mortality rates. An increasing number of studies have demonstrated shared...Full Text Available

2011-01-01

346

Calculations of physical and chemical reactions produced in irradiated water containing DNA  

Energy Technology Data Exchange (ETDEWEB)

Initial results obtained with a Monte Carlo computer program designed to link initial physical events in irradiated liquid water with subsequent chemical and biological events are presented. 10 refs., 4 figs., 3 tabs.

1985-01-01

347

CDC - Seasonal Influenza (Flu) - Questions and Answers - Guillain...  

Science.gov (United States)

Effectiveness Flu Shot Nasal Spray Vaccine (LAIV) Thimerosal Guillain-Barré Syndrome (GBS) Antiviral Drugs: Key Facts Antiviral Drugs: Q&A Antiviral Drug Resistance Links,...

2011-09-24

348

Biodiversity and body size are linked across metazoans  

UK PubMed Central (United Kingdom)

Body size variation across the Metazoa is immense, encompassing 17 orders of magnitude in biovolume. Factors driving this extreme diversification in size and the consequences of size variation for biological...Full Text Available

2009-06-22

349

Beverage patterns and trends among school-aged children in the US, 1989-2008  

UK PubMed Central (United Kingdom)

BackgroundHigh intake of sugar-sweetened beverages in childhood is linked to increased risk of obesity and type II diabetes later in life. Using three nationally representative surveys...Full Text Available

350

BUBL LINK: Vietnam  

Wastenet

... Author: Vets With A Mission Subjects: vietnam, vietnam war, warfare DeweyClass: 959.7043 Resource ... Subjects: vietnam, vietnam war DeweyClass: 959.7 Resource type: bibliography, index World Travel ...

351

BUBL LINK: Library organisations  

Wastenet

...6 Resource type: documents MmIT: Multimedia Information and Technology Group Group aiming to facilitate communication between CILIP members interested in multimedia developments in the library and information science field. Visits to places of interest like museums and archives are frequently organised, and an email discussion list ...

352

Association of Paraoxonase 1 (PON1) polymorphisms with osteoporotic fracture risk in postmenopausal Korean women  

UK PubMed Central (United Kingdom)

There is increasing evidence of a biochemical link between lipid oxidation and bone metabolism. Paraoxonase 1 (PON1) prevents the oxidation of low-density lipoprotein (LDL) and metabolizes biologically...Full Text Available

2011-02-28

353

Are Petals Sterile Stamens or Bracts? The Origin and Evolution of Petals in the Core Eudicots  

UK PubMed Central (United Kingdom)

BackgroundThe aim of this paper is to discuss the controversial origins of petals from tepals or stamens and the links between the morphological expression of petals and floral organ...Full Text Available

2007-09-01

354

Aquatic Resource Monitoring  

Wastenet

...research strategy and plans Aquatic resource monitoring research programs, EMAP and STAR grants Go To EMAP homepage Go To Top Bibliography References for survey designs, statistical analyses , program documentation, and monitoring reports. Reports, abstracts and links to electronic versions Go To Top Frequently Asked Questions ...

355

Antibody avidity in swine lymphocyte antigen-defined miniature pigs.  

UK PubMed Central (United Kingdom)

Antibody avidity to hen egg white lysozyme (HEWL) was measured by thiocyanate ion elution enzyme-linked immunosorbent assay (ELISA) in swine lymphocyte antigen (SLA) defined miniature pigs. Serum antibody...Full Text Available

1992-10-01

356

Anti-beta-endorphin immunoglobulin G in humans.  

UK PubMed Central (United Kingdom)

Human IgG specific for beta-endorphin was identified by enzyme-linked immunoabsorbent assay and isolated by affinity chromatography. From a sample of 27 subjects, three individuals with major depression...Full Text Available

1986-11-01

357

An Evaluation of the Value of Choice with Preschool Children  

UK PubMed Central (United Kingdom)

The current study examined the reinforcing effects of choosing among alternatives in a four-part evaluation. In the first study, initial-link responses in a concurrent-chains arrangement resulted in...Full Text Available

2006-01-01

358

Amastigote stage-specific monoclonal antibodies against Leishmania major.  

UK PubMed Central (United Kingdom)

Monoclonal antibodies were produced against gamma-irradiated amastigotes of Leishmania major. Five antibodies (T16 through T20) were selected which reacted in enzyme-linked immunoassays with the intracellular...Full Text Available

1989-12-01

359

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes  

UK PubMed Central (United Kingdom)

Acquired resistance to the action of insulin to stimulate glucose transport in skeletal muscle is associated with obesity and promotes the development of type 2 diabetes. In skeletal muscle,...Full Text Available

2008-05-01

360

Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis*  

UK PubMed Central (United Kingdom)

Adipocyte death has been reported in both obese humans and rodents. However, its role in metabolic disorders, including insulin resistance, hepatic steatosis, and inflammation associated with obesity...Full Text Available

2010-01-29

361

A cytochrome P450 terpenoid hydroxylase linked to the suppression of insect juvenile hormone synthesis  

UK PubMed Central (United Kingdom)

A cDNA encoding a cytochrome P450 enzyme was isolated from a cDNA library of the corpora allata (CA) from reproductively active Diploptera punctata cockroaches. This P450 from the endocrine...Full Text Available

1998-10-27

362

A Computerized Hospital to Physician Office Link Based on Readily Available Technology  

UK PubMed Central (United Kingdom)

Most hospitals today are quickly developing special programs and services that are designed to compete for physicians and patients, and ultimately fill unoccupied beds. In an attempt to attract physicians...Full Text Available

1989-11-08

363

1,3-Butadiene: linking metabolism, dosimetry, and mutation induction.  

UK PubMed Central (United Kingdom)

There is increasing concern for the potential adverse health effects of human exposures to chemical mixtures. To better understand the complex interactions of chemicals within a mixture, it is essential...Full Text Available

1994-11-01

364

Use of integrin-linked kinase to extend function of encapsulated pancreatic tissue  

Energy Technology Data Exchange (ETDEWEB)

We have studied the impact of overexpression of an intracellular signaling protein, integrin-linked kinase (ILK), on the survival and function of encapsulated islet tissue used for the treatment of type 1 diabetes. The dimensions of the encapsulated tissue can impact the stresses placed on the tissue and ILK overexpression shows the ability to extend function of dissociated cells as well as intact islets. These results suggest that lost cell-extracellular matrix interactions in cell encapsulation systems can lead to decreased insulin secretion and ILK signaling is a target to overcome this phenomenon. (communication)

2010-12-15

365

The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism  

DEFF Research Database (Denmark)

Several enzymes of the metabolic pathways responsible for metabolism of cytosolic ribonucleotides and deoxyribonucleotides are located in mitochondria. Studies described in this paper suggest dysfunction of the mitochondria to affect these metabolic pathways and limit the available levels of cytosolic ribonucleotides and deoxyribonucleotides, which in turn can result in aberrant RNA and DNA synthesis. Mitochondrial dysfunction has been linked to genomic instability, and it is possible that the limiting effect of mitochondrial dysfunction on the levels of nucleotides and resulting aberrant RNA and DNA synthesis in part can be responsible for this link. This paper summarizes the parts of the metabolic pathways responsible for nucleotide metabolism that can be affected by mitochondrial dysfunction.

2010-01-01

366

Noncommutative tori, Yang-Mills and string theory  

CERN Document Server

Noncommutative tori are among historically the oldest and by now the most developed examples of noncommutative spaces. Noncommutative Yang-Mills theory can be obtained from string theory. This connection led to a cross-fertilization of research in physics and mathematics on Yang-Mills theory on noncommutative tori. One important result stemming from that work is the link between T-duality in string theory and Morita equivalence of associative algebras. In this article we give an overview of the basic results in differential geometry of noncommutative tori. Yang-Mills theory on noncommutative tori, the duality induced by Morita equivalence and its link with the T-duality are discussed. Noncommutative Nahm transform for instantons is introduced.

2005-01-01

367

Networks of companies and branches in Poland  

CERN Document Server

In this study we consider relations between companies in Poland taking into account common branches they belong to. It is clear that companies belonging to the same branch compete for similar customers, so the market induces correlations between them. On the other hand two branches can be related by companies acting in both of them. To remove weak, accidental links we shall use a concept of threshold filtering for weighted networks where a link weight corresponds to a number of existing connections (common companies or branches) between a pair of nodes.

2006-01-01

368

BUBL LINK: Biblical studies  

Wastenet

...com: Christianity: General All-in-One Biblical Resources Search Anno Domini: Jesus Through the Centuries Bible and Homosexuality Bible Reading Fellowship Bible Society Bible ...of the New Testament Vine's Expository Dictionary of New Testament Words Virtual Christianity: Bibles Whole Bible Comments: bubl@bubl.ac.uk About....com: Christianity: General Offers original articles and features about Christianity in general plus annotated links to selected relevant Internet resources, compiled by ... Also includes a gallery of Christian images such as The Last Supper by Leonardo Da Vinci. Author: About....

369

A wrench for screwing and unscrewing lock connections  

Energy Technology Data Exchange (ETDEWEB)

A wrench is proposed for screwing and unscrewing lock connections, which includes a spring loaded base, a faceplate with low moment and high moment mechanisms and subassemblies for moving them. In order to increase the operational reliability, the wrench is equipped with uprights evenly disposed along the perimeter of the base with hinged suspensions for linking the base, the hinged suspension is made in the form of interconnected links for the upper and lower traverses with the hinges. One of the hinges is positioned between the upper traverse and the upright, while the other is located between the lower traverse and the base.

1983-01-01

370

A base for a drilling rig unit  

Energy Technology Data Exchange (ETDEWEB)

The purpose of the invention is to reduce the labor intensity of assembly and disassembly of a drilling rig with a large unit transport method. To achieve the cited goal, in the base of the drilling rig unit, which contains uprights with hinges, installed between the frame and the foundation support, where each of the hinges is linked by a flexible element with the frame, the frame and the foundation support are equipped with encircling elements installed with the capability of interacting with the flexible element, where the uprights are linked with the frame by means of hinges with the capability of locking and the uprights by means of the encircling and flexible elements are connected in pairs.

1983-01-01

371

The role and impact of rubber in poly(methyl methacrylate)/lithium triflate electrolyte  

British Library Electronic Table of Contents (United Kingdom)

In this research, new thin freestanding films of poly(methyl methacrylate) (PMMA)/50% epoxidised natural rubber (ENR 50) were doped with lithium triflate, LiCF3SO3 salt was prepared by a solvent casting method. The incorporation of ENR 50 is found to increase the conductivity of PMMA/LiCF3SO3 by two orders of magnitude at room temperature. The highest conductivity achieved was 5.09x10-5Scm-1 at room temperature when 60% of LiCF3SO3 salt was introduced into the PMMA blend containing 10% ENR 50. The formation of excessive hydrogen bonds and interchain crosslinking limit the performance of the blend at higher concentrations of ENR 50. The ionic conduction mechanisms in PMMA/ENR 50/LiCF3SO3 electrolytes obey the Arrhenius rule in which the ion transport in these materials is thermally assisted...

2006-01-01

372

Synthesis, crystal structure and spectroscopic studies of copper(II) complex of C-meso-1,5,8,12-tetramethyl-1,4,8,11-tetraazacyclotetradecane  

British Library Electronic Table of Contents (United Kingdom)

Copper(II) complex coordinated with cyclam-type macrocyclic tetramine, C-meso-1,5,8,12-tetramethyl-1,4,8,11-tetraazacyclotetradecane (2Cdmc) has been synthesized and characterized by single crystal X-ray crystallographic analysis and UV?Vis absorption spectra. Solved molecular structure of [Cu(2Cdmc)(H2O)]Cl2?2H2O (1) revealed that macrocyclic ligand 2Cdmc was in the most stable trans-III structure, but the C-methyl groups of 2Cdmc adopted energetically unfavorable axial configuration (C-axial). This complex 1 is the second example of complex of cyclam-type tetramine with only axially oriented C-methyl groups. This complex adopted five-coordinated square-pyramidal geometry with one water molecule occupying one of the two apical sites. Network of hydrogen bonds involving counter anions (Cl?...

2011-01-01

373

Synthesis of model compounds for coal liquefaction research. Quarterly report No. 1, June 21, 1990--September 20, 1990  

Science.gov (United States)

The objectives of this project are to develop feasible synthetic routes to produce (1) 4(4`-hydroxy-5`,6`,7`,8`-tetrahydro-l`-naphthylmethyl )- 6-methyldibenzothiophene, and (2) a 1-hydroxynaphthalene-benzothiophene polymer. Our experimental work during this quarter concentrated on. As several possible synthetic routes to the target molecule, 4(4`-hydroxy-5`,6`,7`,8`-tetrahydro- l`-naphthylmethyl )-6-methyldibenzothiophene. We tried synthesizing the intermediates for our first method, in which we couple a metalated 4-methyldibenzothiophene with 4-formyl-5,6,7,8-tetrahydro-1-naphthol. We found that we could easily metalate dibenzothiophene, and then add a methyl group to the 4-position to give 4-methyldibenzothiophene in greater than 80% yield by using t-butyllithium in tetrahydropyran followed by dimethylsulfate. However, adding the second metal to the desired 4` position using the same method was more difficult, and instead the reaction occurred on the ...

1990-11-02

374

Studies of initial stage in coal liquefaction. Effect of decomposition of oxygen-functional groups on coal liquefaction; Ekika hanno no shoki katei ni kansuru kenkyu. 3. Gansanso kannoki no bunkai kyodo to ekika hanno eno eikyo  

Energy Technology Data Exchange (ETDEWEB)

Pretreatment of brown coal in oil was conducted using 1-methyl naphthalene or mixture of tetralin and 1-methyl naphthalene as solvent at temperatures ranging from 300 to 430{degree}C under nitrogen atmosphere. Effects of the solvent properties on the structural change of oxygen-functional groups (OFG) and coal liquefaction were investigated by means of quantitative analysis of OFG and solid state {sup 13}C-NMR measurement. When hydrogen transfer from solvent was insufficient, it was suggested that brown coal molecules loose their hydrogen to be aromatized. While, at lower temperatures ranging from 300 to 350{degree}C, hydrogen contained in brown coal molecules was consumed for the stabilization of pyrolytic radicals, and the deterioration of liquefaction was not observed. When hydrogen transfer from solvent was insufficient at higher temperatures above 400{degree}C in nitrogen atmosphere during pretreatment in oil, crosslinking like benzofuran ...

1996-10-28

375

Stereospecific ligands and their complexes. Part VII. Synthesis, characterization and in vitro antitumoral activity of platinum(II) complexes with O,Oprime-dialkyl esters of (S,S)-ethylenediamine-N,Nprime-di-2-(4-methyl)pentanoic acid  

British Library Electronic Table of Contents (United Kingdom)

Platinum(II) complexes (1-4) with bidentate N,Nprime-ligands, O,Oprime-dialkyl esters (alkyl = ethyl, n-propyl, n-butyl and n-pentyl), of (S,S)-ethylenediamine-N,Nprime-di-2-(4-methyl)pentanoic acid were synthesized and characterized by IR, 1H NMR and 13C NMR spectroscopy and elemental analysis. DFT calculations were performed for the complexes and it was found that only one diastereoisomer could be formed. Cytotoxic activity of complexes 1-4 was determined against chronic lymphocytic leukemia cells (CLL) and compared to the activity of ligand precursors L12HCl-L42HCl and corresponding palladium(II) complexes, [PdCl2L] (L = L1-L4). The complexes were found to exhibit significantly higher antitumor activities than cisplatin on CLL cells. Cytotoxic effect of platinum(II) complexes on CLL cel...

2011-01-01

376

Radionuclear estimation with {sup 99m}Tc-N-pyridoxyl-5-methyl-tryptophan (PMT) scintigraphy of recurrent hepatocellular carcinoma after non-surgical treatment  

Energy Technology Data Exchange (ETDEWEB)

{sup 99m}Tc-N-pyridoxyl-5-methyl-tryptophan (PMT) scintigraphy, which exhibits highly specific for the diagnosis of primary hepatocellular carcinoma (HCC), was performed for recurrent HCC following non-surgical treatment. Eighty-four patients (total 351 examinations) were selected for the study. The ability of PMT scintigraphy to diagnose recurrent HCC after treatment was compared with that of computed tomography, ultrasonography and angiography. The results showed that sixty-three (75%) of 84 cases demonstrated positive findings during our follow-up period, most of the tumors initially showing positive findings remained PMT positive when they recurred and PMT studies shortly after treatment demonstrated wider tracer uptake rather than the actual tumor area. In conclusion, PMT scintigraphy for patients with HCC after non-surgical treatment exhibited high accuracy in identifying viable HCC only for tumors indicating positive findings. (author)

1997-10-01

377

Radiolytic stabilization of poly(methyl methacrylate) using commercial additives; Estabilizacao radiolitica do poli(metacrilato de metila) usando aditivos comerciais  

Energy Technology Data Exchange (ETDEWEB)

Poly(methyl methacrylate), PMMA, Acrigel, a Brazilian polymer, is used in the manufacture of medical supplies sterelizable by ionizing radiation. However, when PMMA is gamma-irradiated it undergoes main chain scissions, which promote molecular degradation causing reduction in its mechanical properties. Therefore, radiolytic of PMMA is important for it to become commercially radiosterizable. In this work some commercial additives, originally used in photo-and thermo-oxidate stabilization of polymers, were tested. Only two additives, type HALS (Hindered Amine Light Stabilizer), denoted Scavenger, showed a good protective quality. The investigation of radiation-induced main scissions was carried out by viscosimetric method. The most effective additive, added to the polymer system at 0.3 w/w%, promotes a great molecular radioprotection of 93%. That means a reduction of G-value (scissions/100 eV) from 0.611 to 0.053. In addition, the glassy transition temperature (T{sub ...

2000-04-01

378

Production of bone cement composites: effect of fillers, co-monomer and particles properties  

International Nuclear Information System (INIS)

Artificial bone cements (BCs) based on poly(methyl methacrylate) (PMMA) powders and methyl methacrylate (MMA) liquid monomer also present in their formulation small amounts of other substances, including a chemical initiator compound and radiopaque agents. Because inadequate mixing of the recipe components during the manufacture of the bone cement may compromise the mechanical properties of the final pieces, new techniques to incorporate the fillers into the BC and their effect upon the mechanical properties of BC pieces were investigated in the present study. PMMA powder composites were produced in situ in the reaction vessel by addition of X-ray contrasts to the reacting MMA mixture. It is shown that this can lead to much better mechanical properties of test pieces, when compared to standard bone cement formulations, because enhanced dispersion of the radiopaque agents can be achieved. Moreover, it is shown that the addition of hydroxyapatite ...

379

Preparation of new proton exchange membrane based on self-assembly of poly(styrene-co-styrene sulfonic acid)-b-poly(methyl methacrylate)/poly(vinylidene fluoride) blend  

Energy Technology Data Exchange (ETDEWEB)

Amphiphilic block copolymers are synthesized by sulfonation of poly(styrene-b-methyl methacrylate) (PS-b-PMMA) using acetyl sulfate, and are blended with poly(vinylidene fluoride) (PVDF) to prepare a new proton exchange membrane, in which PMMA is miscible with PVDF. The morphology and the transport properties of the membranes are investigated as functions of the degree of sulfonation as well as the blend ratio. Notable transition of phase-separated morphology is observed as the PVDF content of the blend is increased. Both the proton conductivity and the ion-exchange capacity (IEC) of the membrane increase with increasing the degree of sulfonation of PS-b-PMMA, and they are also enhanced as the phase-separated domains of blend membrane are well-ordered. Unlike the Nafion membrane, the proton conductivity of the blend membrane increases up to 90 C, indicating the blend membrane shows better thermal stability than the Nafion membrane. (author)

2009-03-01

380

Preliminary study on the thermal conductivity and flammability of WPC based on some tropical woods  

Energy Technology Data Exchange (ETDEWEB)

Selected local woods and their wood-polymer combinations or composites (WPC) were tested for their thermal conductivity and their fire resistance. WPC were prepared by polymerizing monomers ''in situ'' in oven dried woods by gamma radiation. The monomers included acrylonitrile (AN), 60% styrene-40% acrylonitrile (STAN), methyl methacrylate (MMA), 95% methyl methacrylate-5% dioxane (MD), and vinylidene chloride (VDC). A reduction in thermal conductivity was exhibited by all the composites prepared. W-PAN showed the greatest reduction in thermal conductivity and W-PSTAN in general showed the least. An explanation is suggested for this behaviour. The polymers PMMA and PMD were found to enhance flammability of the woods while PVDC, PAN, and PSTAN imparted fire resistance to the woods. Of the six local woods studied, Ramin-and-Keruing-polymer composites showed the highest flammable tendencies obtained. The ...

1985-01-01

381

New Lactone and Xanthone Derivatives Produced by a Mangrove Endophytic Fungus Phoma sp. SK3RW1M from the South China Sea  

British Library Electronic Table of Contents (United Kingdom)

A new lactone, 1,8-dihydroxy-10-methoxy-3-methyldibenzo[b,e]oxepine-6,11-dione (1), and two new xanthones, 1-hydroxy-8-(hydroxymethyl)-6-methoxy-3-methyl-9H-xanthen-9-one (2) and 1-hydroxy-8-(hydroxymethyl)-3-methoxy-6-methyl-9H-xanthen-9-one (3), were isolated from a mangrove endophytic fungus Phoma sp. SK3RW1M collected from the South China Sea. This is the first report on xanthone derivatives isolated as secondary metabolites from Phoma species. Their structures were elucidated by spectroscopic methods, mainly 1D- and 2D-NMR techniques, and the structure of compound 2 was confirmed by X-ray crystallography. Cytotoxicity assays showed that compounds 1-3 were inactive against KB and KBv200 cells.

2010-01-01

382

Method for preparing drilling solutions that are resistant in Zechstein deposits  

Energy Technology Data Exchange (ETDEWEB)

The patent is for a method of preparing drilling muds that are notable for their chemical resistance to Zechstein deposits, especially to magnesium, carbonate and carboxylic acid ions. To achieve chemical resistance of the drilling mud to Zechstein deposits, it is suggested to saturate them with salt (the amount of added salt depends on the absorption properties of the solution), and then to process them with caustic soda or potassium oxide hydrate and lime in proportions that would cause filtrate alkalinity not to exceed 0.5. For example, to prepare drilling solution to bore through mediums containing magnesium salts, potassium salts, rock salt, anhydrate, dolomite, limestone, red salt clay: add 340 kg potassium chloride into 1 m/sup 3/ drilling solution with weighed bentonic clay, 10 kg. ferro-chromate lignosulfite, 7 kg. unslaked lime, 2 kg. sodium hydroxide, 5 kg. carboxy-methyl-cellulose, 5 kg. carboxy-methyl-hydroxylethyl-cellulose, 50 ...

1980-05-31

383

Manufacture of wood/plastic composites by radiation  

International Nuclear Information System (INIS)

The manufacture and use of wood/plastic composite (WPC) as an example of wood matrix and wood sawdust/plastic composites (SDP) as an example of plastic matrix are reviewed. The raw material for WPC are mostly vinyl monomers, particularly methyl methacrylate and styrene. The reaction in WPC polymerization is radical polymerization. Researches on the radiation sources mostly resulted in gamma-ray. Electron beam can be applied only to thin products. The future use of WPC may be for furnitures, sporting goods, decorative parts and the like. Vital study on the reduction of manufacturing costs is required, for example, the improvement of reaction and the adoption of continuous process must be considered. The raw materials for SDP are wood sawdust, vinyl monomer (mostly methyl methacrylate) and resins. Electron beam accelerators are the most preferable radiation source because of its high efficiency and safe operation. SDP shows good forming property. ...

1976-01-01

384

Epigenomic disruption: the effects of early developmental exposures.  

Science.gov (United States)

Through DNA methylation, histone modifications, and small regulatory RNAs the epigenome systematically controls gene expression during development, both in utero and throughout life. The epigenome is also a very reactive system; its labile nature allows it to sense and respond to environmental perturbations to ensure survival during fetal growth. This pliability can lead to aberrant epigenetic modifications that persist into later life and induce numerous disease states. Endocrine-disrupting compounds (EDCs) are ubiquitous chemicals that interfere with growth and development. Several EDCs also interfere with epigenetic programming. The investigation of the epigenotoxic effects of bisphenol A (BPA), an EDC used in the production of plastics and resins, has further raised concern over the impact of EDCs on the epigenome. Using the Agouti viable yellow (A(vy)) mouse model, dietary BPA exposure was shown to hypomethylate both the A(vy) and the Cabp(IAP) metastable ...

2010-10-01

385

Endonuclease IV of Escherichia coli is induced by paraquat  

International Nuclear Information System (INIS)

The addition of paraquat (methyl viologen) to a growing culture of Escherichia coli K-12 led within 1 hr to a 10- to 20-fold increase in the level of endonuclease IV, a DNase for apurinic/apyrimidinic sites. The induction was blocked by chloramphenicol. Increases of 3-fold or more were also seen with plumbagin, menadione, and phenazine methosulfate. H_2O_2 produced no more than a 2-fold increase in endonuclease IV activity. The following agents had no significant effect: streptonigrin, nitrofurantoin, tert-butyl hydroperoxide, #gamma# rays, 260-nm UV radiation, methyl methanesulfonate, mitomycin C, and ascorbate. Paraquat, plumbagin, menadione, and phenazine methosulfate are known to generate superoxide radical anions via redox cycling in vivo. A mutant lacking superoxide dismutase was unusually sensitive to induction by paraquat. In addition, endonuclease IV could be induced by merely growing the mutant in pure O_2. The levels of endonuclease ...

386

Dihydroxybenzene/benzoquinone-containing polymers: organic redox polymers  

Energy Technology Data Exchange (ETDEWEB)

Polymers containing hydroquinone, catechol or their corresponding benzoquinones are a special class of redox polymers. Three pathways of their syntheses are possible: condensation polymerization of suitable monomers, addition polymerization of vinyl monomers containing redox moiety, and chemical attachment of redox unit onto pre-made polymeric matrix. A range of functionalized matrices have been employed such as polyethers, polyesters, polycarbonates, polyurethanes, polyamides and others. Protection of their phenolic functionality has conducted to chemically interesting redox polymer precursors. The presence of a redox moiety coupled with the extant functionalization of the polymer matrix makes the materials very valuable, of wide properties and consequently of vast applicability. For instance, in the oil field, some polymers such as carboxy-methyl-cellulose (CMC) are often applied as to bring about a viscosity improvement and therefore to facilitate the oil ...

2000-08-01

387

Cluster-assisted multiple ionization of methyl iodide by a nanosecond laser: Influence of laser intensity on the kinetic energy and peak profile of multicharged ions  

International Nuclear Information System (INIS)

The dependences of kinetic energies and peak profiles of multicharged ions of I "q"+ (q = 2-3) and C"2"+ on the laser intensity have been studied in detail by time-of-flight mass spectrometry, those multicharged ions are produced by irradiation of methyl iodide cluster beam with a nanosecond 532 nm Nd-YAG laser. Our experiments show that the kinetic energies released of multicharged ions increase linearly with the laser intensity in the range of 3 x 10"9-2 x 10"1"1 W/cm"2. The peaks of multicharged ions are split to forward ions and backward ions, and the ratio of the backward ions to forward ions decreases exponentially with laser intensity. The decreasing of backward ions is probably due to Coulomb scattering by the heavier I"+ ions when they turn around through the laser focus point. The linear dependence of kinetic energy of multicharged ions on laser intensity is interpreted by the ionization mechanism, in which the laser induced inverse bremsstrahlung heating ...

2006-03-20

388

Characterization of 3-["1"2"3I]iodo-L-#alpha#-methyl tyrosine (["1"2"3I]IMT) transport into human Ewing's sarcoma cells in vitro  

International Nuclear Information System (INIS)

3-["1"2"3I]Iodo-L-#alpha#-methyl tyrosine (["1"2"3I]IMT) scintigraphy of extracranial malignant tumors has been described, but little is known about the transport systems involved in ["1"2"3I]IMT uptake into extracranial tumor cells. Here, the precise kinetics of ["1"2"3I]IMT transport into human Ewing's sarcoma cells (VH-64) was determined. The apparent Michaelis constant was of high affinity value (K_m=41.7#+-#3.9 #mu#M) and maximum transport velocity amounted to V_m_a_x=20.7#+-#0.6 nmol#centre dot#mg protein"-"1#centre dot#10 min"-"1. Inhibition experiments revealed the predominance of ["1"2"3I]IMT uptake via sodium-independent system L.

2001-02-01

389

Analysis of forward mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in the bacteriophage P22 mnt repressor gene  

Energy Technology Data Exchange (ETDEWEB)

We describe the isolation and genetic characterization of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced mutations in the phage P22 mnt repressor gene cloned in plasmid pBR322. Mutations in the mnt repressor gene or its operator on this plasmid, pPY98, confer a tetracycline resistance phenotype, whereas the wild-type plasmid confers tetracycline sensitivity. Cells carrying pPY98 were briefly exposed to MNNG to give 20 to 40% survival and a 50- to 100-fold increase in tetracycline-resistant cells. DNA sequence analysis showed that 29 to 30 MNNG-induced mutations were GC-to-AT transitions and one was an AT-to-GC transition. About 80% of the mutations are in three hotspots. This mutation spectrum is consistent with the proposed mechanism of mutagenic action of MNNG, which involves mispairing of an alkylated base, O/sup 6/-methylguanine. The mnt gene may be a useful target for determining mutagenic specificity at the nucleotide level because (i) forward ...

1986-04-01

390

An overview of PETC`s gas-to-liquids technology R&D Program  

Energy Technology Data Exchange (ETDEWEB)

The overall goal of the Gas-to-Liquids Program at the U.S. Department of Energy`s Pittsburgh Energy Technology Center (PETC) is to develop technologies for the production of hydrocarbon fuels and premium chemicals from light alkane gases. PETC`s current Gas-to-Liquids Program comprises the development of four primary advanced conversion technologies, namely, partial oxidation, oxidative coupling, oxyhydrochlorination, and novel conversion processes. Based on the current state of development, it can be concluded that, in the near future, one or more of these technologies will reach proof-of-concept demonstration. Oxyhydrochlorination is the most advanced direct conversion technology, and the synthesis of lower cost methyl chloride from natural gas would impact several commercial technologies that utilize methyl chloride as an intermediate to high value products. Technology development for the partial oxidation of methane to synthesis gas using ...

1995-04-01

391

Wood-plastic composites with high toughness and dimensional stability  

International Nuclear Information System (INIS)

Using acrylic-group containing isocyanates together with methyl methacrylate as impregnating mixture and gamma rays for curing wood-plastic composites have been produced, which show high-dimensional stability and toughness (low brittleness) compared to commonly used wood-plastics. The syntheses of proper acrylic-group containing isocyanates are as well described as the properties of the produced composites, made from maple wood. Also the direct use of the initial compounds, necessary for the syntheses, resulted in products of similar properties. These wood-plastic composites are to be suggested for the production of high-class products, e.g. wood-wind instruments. (author).

1982-10-01

392

Two new paeciloxocins from a mangrove endophytic fungus Paecilomyces sp.  

British Library Electronic Table of Contents (United Kingdom)

Paeciloxocins A and B (2-(1-hydroxy-3-methylbutyl)- and 2-(1-acetoxy-3-methylbutyl)- 11-hydroxy-9-methyl-1-methoxy-5H,7H-dibenzo[b,g]-1,5-dioxocin-5-ones), viz., two new metabolites, were isolated from the mangrove fungus Paecilomyces sp. collected from the Taiwan Strait. Their structures were elucidated by spectral methods. Paeciloxocin A exhibited strong cytotoxicity against the hepG2 cell line.

2010-01-01

393

Sound absorption of tropical woods and their radiation-induced composites  

International Nuclear Information System (INIS)

This is a preliminary study on the sound absorption properties of two tropical hardwoods, Light Red Meranti and Ramin, and their wood-polymer composites. Sound absorption is measured using a standing wave apparatus. The samples are of one thickness (7 mm) and cut longitudinally. Wood-polymer composites are made by impregnating the samples with methyl methacrylate which is polymerized in situ through #gamma#-irradiation. Both woods and their composites are better sound absorbers at higher sound frequencies. With partial impregnation, the absorption coefficients are improved upon particularly in the region between 1-3 kHz. (author).

1988-01-01

394

Resistance of radiation-induced tropical wood-polymer composites to fungal degradation  

Energy Technology Data Exchange (ETDEWEB)

The resistance of six tropical hardwoods to fungal degradation by two wild-type strains of Phanerochaete chrysosporium Burdsall was investigated using vermiculite burial and wood-block weight loss techniques. Radiation-induced wood-polymer composites (WPC), based on two hardwoods Ramin and Rubberwood with methyl methacrylate, were prepared, and samples were also exposed to the wood-rotting fungus. A significant improvement in resistance to fungal decay was observed in the WPC. Scanning-electron micrographs of the two woods and their composites after fungal degradation are presented and discussed.

1987-01-01

395

Microbuckling compression failure of a radiation-induced wood/polymer composite  

Energy Technology Data Exchange (ETDEWEB)

A wood/polymer composite was produced by impregnating Ramin wood with methyl methacrylate monomer and subsequently polymerizing it by gamma irradiation. To assess the improvement in compression strength of the wood caused by the polymer impregnation, a microbuckling compression failure mechanism was used to model the compression failure of the composite. Such a mechanism was found to predict a linear relationship between the compression strength and the percentage polymer impregnation (by weight). Uniaxial compression test results at 45({plus minus}5)% and 90({plus minus}5)% relative humidity levels, after being statistically analysed, showed that such a linear relationship was valid for up to 100% polymer impregnation. (author).

1990-01-01

396

Microbuckling compression failure of a radiation-induced wood/polymer composite  

International Nuclear Information System (INIS)

A wood/polymer composite was produced by impregnating Ramin wood with methyl methacrylate monomer and subsequently polymerizing it by gamma irradiation. To assess the improvement in compression strength of the wood caused by the polymer impregnation, a microbuckling compression failure mechanism was used to model the compression failure of the composite. Such a mechanism was found to predict a linear relationship between the compression strength and the percentage polymer impregnation (by weight). Uniaxial compression test results at 45(#+-#5)% and 90(#+-#5)% relative humidity levels, after being statistically analysed, showed that such a linear relationship was valid for up to 100% polymer impregnation. (author).

1990-01-01

397

Mechanism of biodegradation of paraquat by Lipomyces starkeyi  

Energy Technology Data Exchange (ETDEWEB)

The biodegradation of ring-/sup 14/C- and methyl-/sup 14/C-labeled paraquat by the soil yeast Lipomyces starkeyi was studied in vitro. It was found that the degradation of paraquat (acting as a sole source of culture nitrogen) resulted in the accumulation in the extracellular medium of radiolabeled acetic acid. The culture also evolved radiolabeled CO/sub 2/. The results suggest that the degradation of paraquat by L. starkeyi is associated with the integrity of the cell wall and that disruption or removal of the wall results in a complete loss of degradative capability. A mechanism for the degradation of paraquat by this organism is postulated.

1985-05-01

398

Mechanism of biodegradation of paraquat by Lipomyces starkeyi  

International Nuclear Information System (INIS)

The biodegradation of ring-"1"4C- and methyl-"1"4C-labeled paraquat by the soil yeast Lipomyces starkeyi was studied in vitro. It was found that the degradation of paraquat (acting as a sole source of culture nitrogen) resulted in the accumulation in the extracellular medium of radiolabeled acetic acid. The culture also evolved radiolabeled CO_2. The results suggest that the degradation of paraquat by L. starkeyi is associated with the integrity of the cell wall and that disruption or removal of the wall results in a complete loss of degradative capability. A mechanism for the degradation of paraquat by this organism is postulated.

399

Long non-coding RNAs in nervous system function and disease  

British Library Electronic Table of Contents (United Kingdom)

Central nervous system (CNS) development, homeostasis, stress responses, and plasticity are all mediated by epigenetic mechanisms that modulate gene expression and promote selective deployment of functional gene networks in response to complex profiles of interoceptive and environmental signals. Thus, not surprisingly, disruptions of these epigenetic processes are implicated in the pathogenesis of a spectrum of neurological and psychiatric diseases. Epigenetic mechanisms involve chromatin remodeling by relatively generic complexes that catalyze DNA methylation and various types of histone modifications. There is increasing evidence that these complexes are directed to their sites of action by long non-protein-coding RNAs (lncRNAs), of which there are tens if not hundreds of thousands speci...

2010-01-01

400

Effect of additives in the positive active mass of lead batteries. Zur Wirkung von Zusaetzen in der positiven Aktivmasse des Bleiakkumulators  

Energy Technology Data Exchange (ETDEWEB)

In order to improve the capacity and service life of cathodes, the effect of carboxy-methyl cellulose, soot, silica gel and fibres was examined. Structural tests and electrical and electro-chemical measurements are used for this. The additives can affect crystallization in the manufacturing stage of the electrodes and can increase the storage capacity for water and the electronic conductivity. They act to stabilize the mass in cyclic operation. Soot additive has little effect on the properties of the electrode, but the other substances increase the service life or the use of the mass. (LU).

1984-01-01

401

Development of superconducting cryo-electron microscope and its applications  

International Nuclear Information System (INIS)

Recently, a superconducting cryo-electron microscope in which specimens are cooled to the liquid helium temperature (4.2 K) has been developed. The main components and functional features of this new microscope are reported together with application data on polyethylene, poly (4-methyl-1-pentene), valonia cellulose, rock salt, ice crystallites and ceramic superconductor. The resistance to electron radiation damage, of beam-sensitive specimens including polymers has been increased more than ten times. Thus, the microscope has made it possible to take high resolution images and to analyze the crystal-structure of micro-areas. (orig.).

1988-01-01

402

Complexing of ruthenium during sorption by a graft copolymer of a polyacrylonitrile fiber with poly-2-methvl-5-vinylpyridine (PAN-MVP)  

Energy Technology Data Exchange (ETDEWEB)

This paper studies the sorption of chlorine complexes of ruthenium (IV) on the graft copolymer of a polyacrylonitrile fiber with poly-2-methyl-5-vinylpyridine (PAN-MVP). The composition of the fiber is illustrated. It is shown that sorption of chlorine complexes of ruthenium (IV) from acid solutions by a pyridine fiber sorbent takes place according to an anion-exchange mechanism and is due to the formation of compounds of the diamine type (Ru(RPy)/sub 2/Cl/sub 4/).

1985-05-20

403

Chemical constituents of Galianthe brasiliensis (Spreng.) E.L.Cabral and Bacigalupo (Rubiaceae)  

International Nuclear Information System (INIS)

This paper describes the chemical constituents isolated from aerial parts of the plant Galianthe brasiliensis. From a methanol extract, the iridoid glycosides asperuloside, deacetylasperuloside, mixture of Z- and E-6-O-p-coumaroylscandoside methyl ester, the triterpene ursolic acid and the steroids stigmasterol, campesterol, b-sitosterol and 3-O-b-glucopyranosyl sitosterol were isolated. The structures of the natural products were identified on the basis of spectral data, including 2D NMR experiments. The antiproliferative properties of the crude methanolic extract were investigated against a series of nine human cancer cell lines. (author)

404

Synthesis and PET imaging of the benzodiazepine receptor tracer [N-methyl-"1"1C]iomazenil  

International Nuclear Information System (INIS)

The central benzodiazepine receptor tracer [N-methyl-"1"1C]iomazenil (Ro 16-0154) was synthesized by alkylation of the desmethyl precursor noriomazenil with ["1"1C]methyl iodide. The ["1"1C]CH_3I (prepared by reduction of ["1"1C]CO_2 with LiAlH_4 followed by reaction with HI) was reacted with noriomazenil inN,N -dimethylformamide and Bu_4N"+OH"- for 1 min at 80 deg. C and purified by HPLC (C_1_8, 34% CH_3CN/H_2O, 7 mL/min). The product was obtained with synthesis time 35 #+-# 5 min (mean #+-# SD, n = 7), radiochemical yield (EOB) 36 #+-# 16%, radiochemical purity 99 #+-# 1%, and specific activity 5100 #+-# 2800 mCi/#mu#mol. Absorbed radiation doses were calculated from previously acquired human biodistribution data. The urinary bladder wall received the highest dose (0.099 mGy/MBq) for 4.8 h voiding interval and the effective dose equivalent was 0.015 mSv/MBq. After i.v. injection of ["1"1C]iomazenil in an adult baboon or healthy human ...

1995-07-01

405

Fluoride complexes of Pt(II) as nucleophiles: activity of PtCl/sub 4//sup 2 -/, PtCl/sub 3/(H/sub 2/O)/sup -/, and PtCl/sub 3/(C/sub 2/H/sub 4/)/sup -/ anions in the oxidative addition of methyl iodide  

Energy Technology Data Exchange (ETDEWEB)

The kinetics of the oxidative addition of CH/sub 3/I to platinum(II) complexes in aqueous solutions of K/sub 2/PtCl/sub 4/ and KPtCl/sub 3/(C/sub 2/H/sub 4/) have been studied by PMR and GLC. The second-order rate constants for the PtCl/sub 3/(H/sub 2/O)/sup -/ and PtCl/sub 4//sup 2 -/ particles are equal to 400 exp(-2.7 x 10/sup 3//T) and 3.18 x 10/sup 10/ exp(-9.2 x 10/sup 3//T) mole/sup -1/ x liter x sec/sup -1/, respectively. The introduction of a ..pi..-acceptor ligand, viz. ethylene, into the coordination sphere of platinum(II) results in a sharp drop in the rate, probably due to a decrease in the electron density on the platinum atom. According to the PMR data, the product of the oxidative addition of CH/sub 3/I to Zeise's salt is a methyl complex of platinum(IV), is identical to the complex obtained by reacting methyl iodide with K/sub 2/PtCL/sub 4/, and does not contain an olefin.

1987-05-01

406

Computerized tomography-guided neurolytic splanchnic nerve block  

International Nuclear Information System (INIS)

Computerized tomography-guided neurolytic splanchnic nerve block is a technique for relieving abdominal cancer pain; the goal is the alcoholic neurolytic interruption of the sensitive structures in retroperitoneal space. Computerized tomography yields accurate anatomical detailing and the course for needle placement and alcohol spread. January, 1993, to July, 1996, twenty-one bilateral splanchnic nerve blocks were performed through the posterior access. Forty-eight hours after alcoholism. 14 patients (66%) had complete pain regression; 52% of the patients needed no analgesics for 6 to 54 days and only 9 patients (42%) needed another low opioid therapy. Complications included hypotension and diarrhea in all cases. One had a cardiac arrest and diet 8 days after the procedure. There were no other complications. The whole procedure usually lasted 60 min (range: 45 to 90 min). Splanchnic nerve neurolysis is a useful treatment in the patients with severe chronic abdominal pain. It is used as ...

1997-01-01

407

An Arabidopsis thaliana methyltransferase Capable of Methylating Farnesoic Acid  

Energy Technology Data Exchange (ETDEWEB)

We previously reported the identification of a new family of plant methyltransferases (MTs), named the SABATH family, that use S-adenosyl-l-methionine (SAM) to methylate a carboxyl moiety or a nitrogen-containing functional group on a diverse array of plant compounds. The Arabidopsis genome alone contains 24 distinct SABATH genes. To identify the catalytic specificities of members of this protein family in Arabidopsis, we screened recombinantly expressed and purified enzymes with a large number of potential substrates. Here, we report that the Arabidopsis thaliana gene At3g44860 encodes a protein with high catalytic specificity towards farnesoic acid (FA). Under steady-state conditions, this farnesoic acid carboxyl methyltransferase (FAMT) exhibits K{sub M} values of 41 and 71 {mu}M for FA and SAM, respectively. A three-dimensional model of FAMT constructed based upon similarity to the experimentally determined structure of Clarkia breweri salicylic acid ...

2006-01-01

408

3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro.  

Science.gov (United States)

The goal of the present work was to determine the impact of N3-methyladenine (3-mA), an important lesion generated by many environmental agents and anticancer drugs, on in vivo DNA replication and in vitro RNA transcription. Due to 3-mA chemical instability, the stable isostere 3-methyl-3-deazaadenine (3-m-c(3)A) was site specifically positioned into an oligodeoxynucleotide. The oligomer was, then incorporated into a vector system that is rapidly converted to ssDNA inside yeast cells and requires DNA replication opposite the lesion for plasmid clonal selection. For control purposes, an adenine or a stable apurinic/apyrimidinic (AP)-lesion was placed at the same site. The presence of each lesion in the oligonucleotide was confirmed by MALDI-TOF analysis. Plasmids were then transfected into yeast cells. While the AP-site dramatically reduced plasmid replication in all strains, the 3-m-c(3)A had a slight effect in the rad30 background which significantly increased ...

2011-06-14

409

Performance following a 500-675 rad neutron pulse. Report for June 1981-January 1984  

Energy Technology Data Exchange (ETDEWEB)

A three-light, three-lever discrete avoidance behavioral task was initiated to study the effects of a 500-675 rad neutron pulse upon performance. Eight primates performed the task for 4 h(3.5 h postexposure) on exposure day and for 4 h on each of 3 d postexposure. For the exposure day, five subjects had a decrease in correct responses, seven had increased reaction times, and six experienced productive emesis within 3.5 hours postexposure. Although the performance degradations were not severe, these data suggest that the performance of time critical tasks could be significantly impaired.

1985-06-01

410

Extraction of rare earths by carbonic acids melts  

Energy Technology Data Exchange (ETDEWEB)

Extraction of rare earths (La, Ce, Pr, Eu, Gd, Er, Yb) from nitrate solutions by melts of carboxylic acids of the C/sub 17/-C/sub 20/ fraction and stearic acid with paraffin, depending on the temperature (60-90 deg), phase contact time and their volume ratio (O:B from 1:5 up to 1:100), pH of the aqueous phase (2-6), rare earth concentration (10/sup -6/-10/sup -3/ m) is studied. It is shown that in the whole concentration range investigated rare earths are extracted quantitatively into the carboxylic acid melt of C/sub 17/-C/sub 20/ fraction at the equilibrium value of pH>=3.8, while into the melt of 0.1 M stearic acid in paraffin at pH>=4.5.

1980-10-01

411

Extraction of americium of different oxidation states in two-phase aqueous system based on polyethylene glycol  

International Nuclear Information System (INIS)

Americium extraction in different oxidation states in two-phase aqueous system based on polyethylene glycol is investigated. Conditions for quantitative extraction of americium (3) and americium (5) from ammonium sulfate solutions within pH=3-5 interval in the presence of arsenazo 3 are found. Composition of the produced americium complexes with reagent is determined; americium (3) interacts with arsenazo 3 in ammonium sulfate solutions with the formation of MeR and Me_2R composition complexes. Absorption spectrum characteristics of americium (3) and- (5) complexes with arsenazo 3 in ammonium sulfate solutions and extracts based polyethylene glycol aqueous solutions are given. Molar extinction coefficients of americium complexes with arsenazo (3) in these solutions are determined.

1987-01-01

412

Enzymatic solubilization of a pectinaceous dietary fiber fraction from potato pulp: Optimization of the fiber extraction process  

British Library Electronic Table of Contents (United Kingdom)

Upgrading of potato pulp, a byproduct stream from industrial manufacture of potato starch, is important for the continued economic competitiveness of the potato starch industry. The major part of potato pulp consists of the tuber plant cell wall material which is particularly rich in galactan branched rhamnogalacturonan I type pectin. In the work reported here, the release of high-molecular weight pectinaceous dietary fiber polysaccharides from starch free potato pulp was accomplished by use of a multicomponent pectinase preparation from Aspergillus aculeatus (Viscozyme L). The enzyme reaction conditions for the solubilization were optimized via a surface response design to be addition of 0.27% Viscozyme L by weight of potato pulp substrate dry matter, 1h treatment at pH 3.5, 62.5degreeC. ...

2009-01-01

413

Crystal structure of the human centromeric nucleosome containing CENP-A  

British Library Electronic Table of Contents (United Kingdom)

In eukaryotes, accurate chromosome segregation during mitosis and meiosis is coordinated by kinetochores, which are unique chromosomal sites for microtubule attachment. Centromeres specify the kinetochore formation sites on individual chromosomes, and are epigenetically marked by the assembly of nucleosomes containing the centromere-specific histone H3 variant, CENP-A. Although the underlying mechanism is unclear, centromere inheritance is probably dictated by the architecture of the centromeric nucleosome. Here we report the crystal structure of the human centromeric nucleosome containing CENP-A and its cognate ?-satellite DNA derivative (147 base pairs). In the human CENP-A nucleosome, the DNA is wrapped around the histone octamer, consisting of two each of histones H2A, H2B, H4 and CENP...

2011-01-01

414

A comparison of thermal maturity parameters between freely extracted hydrocarbons (Bitumen I) and a second extract (Bitumen II) from within the kerogen matrix of Permian and Triassic sedimentary rocks  

British Library Electronic Table of Contents (United Kingdom)

In this study we compared various maturity dependent aromatic, steroid and triterpenoid hydrocarbon ratios in bitumens that are freely extractable from sedimentary rocks (Bitumen I) with those in second extracts that comprised hydrocarbons closely associated with the kerogen/mineral matrix (Bitumen II). Bitumen II was released through kerogen isolation and demineralisation using HCl and HF/H3BO3. The samples studied, although of similar age, come from different localities. They represent a range of facies and two kerogen types (II and III), and all were deposited under marine conditions. The results show that the more stable b isomers of methylnaphthalene (MN) and methylphenanthrene (MP) are relatively more abundant in Bitumen II. The difference between the methylnaphthalene ratio (MNR) of...

2010-01-01

415

New facility design and work method for the quantitative fit testing laboratory. Master's thesis  

Energy Technology Data Exchange (ETDEWEB)

The United States Air Force School of Aerospace Medicine (USAFSAM) tests the quantitative fit of masks which are worn by military personnel during nuclear, biological, and chemical warfare. Subjects are placed in a Dynatech-Frontier Fit Testing Chamber, salt air is fed into the chamber, and samples of air are drawn from the mask and the chamber. The ratio of salt air outside the mask to salt air inside the mask is called the quantitative fit factor. A motion-time study was conducted to evaluate the efficiency of the layout and work method presently used in the laboratory. A link analysis was done to determine equipment priorities, and the link data and design guidelines were used to develop three proposed laboratory designs. The proposals were evaluated by projecting the time and motion efficiency, and the energy expended working in each design. Also evaluated were the lengths of the equipment links for each proposal, and ...

1989-05-01

416

Nature inspired artificial intelligence based adaptive traffic flow distribution in computer network  

CERN Document Server

Because of the stochastic nature of traffic requirement matrix, it is very difficult to get the optimal traffic distribution to minimize the delay even with adaptive routing protocol in a fixed connection network where capacity already defined for each link. Hence there is a requirement to define such a method, which could generate the optimal solution very quickly and efficiently. This paper presenting a new concept to provide the adaptive optimal traffic distribution for dynamic condition of traffic matrix using nature based intelligence methods. With the defined load and fixed capacity of links, average delay for packet has minimized with various variations of evolutionary programming and particle swarm optimization. Comparative study has given over their performance in terms of converging speed. Universal approximation capability, the key feature of feed forward neural network has applied to predict the flow distribution on each ...

2010-01-01

417

Large-scale structure of a nation-wide production network  

CERN Document Server

Production in economy is a set of firms' activities as suppliers and customers; a firm buys goods from other firms, puts added-values and sells products to others in a giant network of production. Empirical study has been lacking despite of the fact that the structure of production network is important to understand and make models for many aspects of dynamics in economy. We study a nation-wide production network comprising a million of firms and millions of supplier-customer links by using recent statistical methods developed in physics. We show in the empirical analysis scale-free degree distribution, disassortativity, correlation of degree to firm-size, and community structure having sectoral and regional modules. Since suppliers usually provide credit to their customers, who supply to theirs in turn, each link is actually a creditor-debtor relation. We also study chains of failures or bankruptcies that take place along those ...

2008-01-01

418

Difference Antenna Selection and Power Allocation for Wireless Cognitive Systems  

CERN Document Server

In this paper, we propose an antenna selection method in a wireless cognitive radio (CR) system, namely difference selection, whereby a single transmit antenna is selected at the secondary transmitter out of $M$ possible antennas such that the weighted difference between the channel gains of the data link and the interference link is maximized. We analyze mutual information and outage probability of the secondary transmission in a CR system with difference antenna selection, and propose a method of optimizing these performance metrics of the secondary data link subject to practical constraints on the peak secondary transmit power and the average interference power as seen by the primary receiver. The optimization is performed over two parameters: the peak secondary transmit power and the difference selection weight $\\delta\\in [0, 1]$. We show that, difference selection using the optimized parameters determined by the ...

2010-01-01

419

Chemical source identifications for natural resource injury/damage assessments and site assessments  

International Nuclear Information System (INIS)

Current regulations guiding technical aspects of natural resource damage assessments combine source, exposure pathway, resource injury, and monetary damage components. In order to associate any observed injury to the uncontrolled release of chemicals (e.g. oil spills, contaminated sediments, in-place toxics, etc.), it is important to link the chemical ''release'' to the injured resource. In complex environmental settings where multiple sources of similar chemicals are combined, multicomponent chemical methods must be used to link the release to the environmental distribution of chemicals. Three examples of the utility of multicomponent organic chemical analyses linked to comprehensive and representative sampling strategies will be discussed--the Shell Martinez Refinery oil spill, the Exxon Valdez oil spill, and a contaminated sediment assessment. These NRDA-based source identifications are based on use of polycyclic ...

1993-11-14

420

Volcanoscope: Scoping study for increasing resilience to hazards in volcanic regions  

Environmental Research Database

ObjectivesProject VOLCANOSCOPE will evaluate strategies (1) for applying existing and new forecasting models to volcanic eruptions, and (2) for identifying methods to improve how forecasts are communicated effectively to vulnerable communities. To link forecasting and communication, the interdisciplinary study will assess how to engage all stakeholders - from monitoring scientists, through emergency agencies, to vulnerable communities - to optimize the understanding of forecasts among different end users. [continued...]DescriptionProject VOLCANOSCOPE will evaluate strategies (1) for applying existing and new forecasting models to volcanic eruptions, and (2) for identifying methods to improve how forecasts are communicated effectively to vulnerable communities. To link forecasting and communication, the interdisciplinary study will assess how to engage all stakeholders - from monitoring scientists, through emergency agencies, to vulnerable ...

2011-01-05

421

The structure of molecular clouds - III. A link between cloud structure and star formation mode  

British Library Electronic Table of Contents (United Kingdom)

Abstract We analyse extinction maps of nearby giant molecular clouds to forge a link between driving processes of turbulence and modes of star formation. Our investigation focuses on cloud structure in the column density range above the self-shielding threshold of 1-mag AV and below the star formation threshold - the regime in which turbulence is expected to dominate. We identify clouds with shallow mass distributions as cluster forming. Clouds that form stars in a less clustered or isolated mode show a steeper mass distribution. Structure functions prove inadequate to distinguish between clouds of different star formation mode. They may, however, suggest that the turbulence in the average cloud is governed by solenoidal forcing. The same is found using the -variance analysis which also in...

2011-01-01

422

The preparation of polyurethane foam combined with pH-sensitive alginate/bentonite hydrogel for wound dressings  

British Library Electronic Table of Contents (United Kingdom)

Polyurethane (PU) foam was combined with protein drug-loaded pH-sensitive alginate-bentonite hydrogel for wound dressings. Alginate is a linear copolymer composed of 1?4-linked ?-D-mannuronic acid (M) and its c-5-epimer ?-Lguluronic acid (G). The amount of (M) and (G) and their sequential distribution are varied depending on the alginate source. Soluble sodium alginate can become a hydrogel when cross-linked with divalent cations and has widespread applications in the food, drink, pharmaceutical and bioengineering industries. Recently, it has been also proposed as a biomaterial for drug delivery systems. Bentonites are the natural inorganic polymers consisting of a large proportion of expandable clay minerals with a three-layer structure such as montmorillonite, beidellite, nontronite, etc...

2011-01-01

423

TUNABLE FIBER FABRY-PEROT FILTER FOR OPTICAL CARRIER-SUPPRESSION AND SINGLE-SIDEBAND MODULATION IN RADIO OVER FIBER LINKS  

British Library Electronic Table of Contents (United Kingdom)

A novel method of simultaneous realization of optical carrier-suppression and single-sideband modulation using fiber Fabry-Perot tunable filter is presented. In order to enhance transmission performance of radio over fiber links, we use a fiber Fabry-Perot tunable filter to filter out one sideband as well as suppress the optical carrier power. The results demonstrate 20.5dB and 14.2dB improvement in the signal noise ratios when 18GHz and 10GHz microwave signals carrying 5Mbit/s quadrature-phase-shift-keyed (QPSK) format data is transmitted over 35 km single mode fiber, respectively.

2006-01-01

424

Symbiotic N2 fixation by legumes growing in pots. 2. Uptake of VN-labelled NO3 , C2H2 reduction and H2 evolution by Trifolium subterraneum L. , Medicago truncatula Gaertn. and Acacia dealbata Link  

Energy Technology Data Exchange (ETDEWEB)

The objectives of this study were to estimate symbiotic nitrogen fixation by two common pasture legumes, Trifolium subterraneum L. and Medicago truncatula Gaertn., and an Australian native legume, Acacia dealbata Link, growing in pots using an indirect isotopic method. This method was also used to calibrate the C2H2 reduction assay of the intact plants. In addition, hydrogen evolution was measured in an attempt to explain the variations in C2H2:N2 ratios between the species. 25 refs.; 1 figure; 4 tabs.

1983-01-01

425

Supporting Children-s Social and Emotional Well-being: Does -Having a Say- Matter?  

British Library Electronic Table of Contents (United Kingdom)

This article argues the importance of ensuring initiatives aimed at improving children-s social and emotional well-being are based on sound participatory principles. The discussion posits links between the recognition of children, dialogic approaches to participation, changing conceptualisations of children and childhood, and children-s well-being. It explores these links in light of one particular initiative, Seasons for Growth (Graham, 1996, 2002, Seasons for Growth; Loss and Grief Education Program. MacKillop Foundation), an education programme built around emerging evidence that giving children a voice assists them to adapt to family change. The paper concludes with insights into what is involved when we locate notions of -having a say- as a key element in promoting children-s well-bei...

2011-01-01

426

References | Radiation Protection | US EPA  

Wastenet

...References | Radiation Protection | US EPA This page provides links to the reference material on EPA's Radiation Protection Web site. U.S. EPA/...OAR/ORIA/Radiation Protection Division Jump to main content. Radiation Protection Contact Us Search: All EPA This Area You are here: EPA Home ... Radiation Protection References PageName Technical Users General Public Reporters Librarians Students/Teachers PROGRAMS TOPICS REFERENCES References The Reference Section provides general material that support the ...other sections of EPA's Radiation Protection Web site. You will find links within the information to related pages throughout the Radiation Protection , EPA ...

427

Processing and characterization of chitosan microspheres to be used as templates for layer-by-layer assembly  

British Library Electronic Table of Contents (United Kingdom)

Chitosan (Ch) microspheres have been developed by precipitation method, cross-linked with glutaraldehyde and used as a template for layer-by-layer (LBL) deposition of two natural polyelectrolytes. Using a LBL methodology, Ch microspheres were alternately coated with hyaluronic acid (HA) and Ch under mild conditions. The roughness of the Ch-based crosslinked microspheres was characterized by atomic force microscopy (AFM). Morphological characterization was performed by environmental scanning electron microscopy (ESEM), scanning electron microscopy (SEM) and stereolight microscopy. The swelling behaviour of the microspheres demonstrated that the ones with more bilayers presented the highest water uptake and the uncoated cross-linked Ch microspheres showed the lowest uptake capability. Micros...

2010-01-01

428

On the relationship between exchange rates and equity returns: A new approach  

British Library Electronic Table of Contents (United Kingdom)

This paper employs a new approach in order to investigate the underlying relationship between stock markets and exchange rates. Current approaches suggest that the relative equity market performance of two countries is linked to their exchange rate. In contrast, this study proposes an alternative approach where one global variable - global equity market returns - is believed to have an effect on exchange rates, with the relative interest rate level of a currency determining the sign of the relationship. Our empirical findings suggest that exchange rates and global stock market returns are strongly linked. The value of currencies with higher interest rates is positively related with global equity returns, whereas the value of currencies with lower interest rates is negatively related with g...

2011-01-01

429

Modelling the work flow of a nuclear waste management program  

Energy Technology Data Exchange (ETDEWEB)

In this paper we describe a modelling project to improve a nuclear waste management program in charge of the creation of a new system for the permanent disposal of nuclear waste. SADT (Structural Analysis and Design Technique) is used in order to provide a work-flow description of the functions to be performed by the waste management program. This description is then translated into a number of Coloured Petri Nets (CPN or CP-nets) corresponding to different program functions where additional behavioural inscriptions provide basis for simulation. Each of these CP-nets is simulated to produce timed event charts that are useful for understanding the behaviour of the program functions under different scenarios. Then all the CPN models are linked together to form a single stand-alone application that is useful for validating the interaction and cooperation between the different program functions. A technique for linking executable CPN models is ...

1997-03-01

430

MPS [More Power Submarine] cables could be MIND [Mass Impregnated Non-Draining Cable] blowing for 1200 MW links  

Energy Technology Data Exchange (ETDEWEB)

ABB High Voltage Cables AB started the MPS (More Power Submarine cables) project in 1993 with a view to exploring new technology opportunities. The goal is to design and type test a submarine HVDC cable for a capacity of 1200 MW at 600 kV. On the day before ABB announced its success in winning the contract for the world`s largest ever submarine HVDC link project for the gigantic Bakun project in Malaysia, ABB Power Systems described progress to date at a symposium in Karlskrona. The proceedings included a test demonstration on an extruded cable which eventually broke down at a stress of over 935 kV -not in the insulation itself but in the end terminations. The electric field was in excess of 200 kV/mm which is higher than ever before reported. (UK)

1996-07-01

431

Human cDNA mapping using fluorescence in situ hybridization  

Energy Technology Data Exchange (ETDEWEB)

Genetic mapping is approached using the techniques of high resolution fluorescence in situ hybridization (FISH). This technology and the results of its application are designed to rapidly generate whole genome as tool box of expressed sequence to speed the identification of human disease genes. The results of this study are intended to dovetail with and to link the results of existing technologies for creating backbone YAC and genetic maps. In the first eight months, this approach generated 60--80% of the expressed sequence map, the remainder expected to be derived through more long-term, labor-intensive, regional chromosomal gene searches or sequencing. The laboratory has made significant progress in the set-up phase, in mapping fetal and adult brain and other cDNAs, in testing a model system for directly linking genetic and physical maps using FISH with small fragments, in setting up a database, and in establishing the validity and throughput ...

1993-03-04

432

FB-Line resin testing final report  

Energy Technology Data Exchange (ETDEWEB)

The Dowex 50W-X8 and 50W-Xl2 resin samples are both strong acid cation materials in the hydrogen form. Each material has a water retention capacity characteristic of its respective marketed degree of cross-linking. Dowex 21K gives confirmatory responses to tests for a strong anion exchange resin in the nitrate form. All three resins have the manufacturer's specified ionic type and form, and the Dowex 50W resins have characteristic water retention capacities. These tests conclude that the ion exchange resins in use in FB-Line meet the approved safety document criteria for cross-linking, ionic form, and resin type.

1992-01-23

433

FB-Line resin testing final report  

Energy Technology Data Exchange (ETDEWEB)

The Dowex 50W-X8 and 50W-Xl2 resin samples are both strong acid cation materials in the hydrogen form. Each material has a water retention capacity characteristic of its respective marketed degree of cross-linking. Dowex 21K gives confirmatory responses to tests for a strong anion exchange resin in the nitrate form. All three resins have the manufacturer`s specified ionic type and form, and the Dowex 50W resins have characteristic water retention capacities. These tests conclude that the ion exchange resins in use in FB-Line meet the approved safety document criteria for cross-linking, ionic form, and resin type.

1992-01-23

434

Deterministic Factors of Stock Networks based on Cross-correlation in Financial Market  

CERN Document Server

The stock market has been known to form homogeneous stock groups with a higher correlation among different stocks according to common economic factors that influence individual stocks. We investigate the role of common economic factors in the market in the formation of stock networks, using the arbitrage pricing model reflecting essential properties of common economic factors. We find that the degree of consistency between real and model stock networks increases as additional common economic factors are incorporated into our model. Furthermore, we find that individual stocks with a large number of links to other stocks in a network are more highly correlated with common economic factors than those with a small number of links. This suggests that common economic factors in the stock market can be understood in terms of deterministic factors.

2007-01-01

435

Association study of SNAP25 and schizophrenia in Irish family and case-control samples  

British Library Electronic Table of Contents (United Kingdom)

SNAP25 occurs on chromosome 20p12.2, which has been linked to schizophrenia in some samples, and recently linked to latent classes of psychotic illness in our sample. SNAP25 is crucial to synaptic functioning, may be involved in axonal growth and dendritic sprouting, and its expression may be decreased in schizophrenia. We genotyped 18 haplotype-tagging SNPs in SNAP25 in a sample of 270 Irish high-density families. Single marker and haplotype analyses were performed in FBAT and PDT. We adjusted for multiple testing by computing q values. Association was followed up in an independent sample of 657 cases and 411 controls. We tested for allelic effects on the clinical phenotype by using the method of sequential addition and 5 factor-derived scores of the OPCRIT. Nine of 18 SNPs had P values <...

2010-01-01

436

Solution conformations of CaCl sub 2 and Ca(NO sub 3 ) sub 2 complexes of chiral tetramethyl 18-crown-6 macrocycles: A 1D and 2D sup 1 H and sup 13 C NMR investigation  

Energy Technology Data Exchange (ETDEWEB)

One- and two-dimensional NMR techniques have been used to investigate the solution structures of (2S,6S,11S,15S)-2,6,11,15-tetramethyl-1,4,7,10,13,16-hexaoxacyclooctadecane (I) and (2R,3R,11R,12R)-2,3,11,12-tetramethyl-1,4,7,10,13,16-hexaoxyacyclooctadecane (II) macrocycle complexes of CaCl{sub 2} and Ca(NO{sub 3}){sub 2} in CDCl{sub 3}. Previous chiroptical studies of these and similar crown complexes by circularly polarized luminescence (CPL), total luminescence (TL), and circular dichroism (CD) spectroscopy have shown that the macrocycle asymmetric carbons in these complexes constrain the ring such that the sense of the ring twist in the S chiral ring complexes is opposite to that in the R chiral ring complexes. These studies have also shown that there is an added chirality element in the di- and trivalent (alkaline earth and lanthanide metal, respectively) nitrate complexes of I and II associated with the twist of the nitrate anions relative to one another as they sterically ...

1989-10-04

437

Developments of PET radioligands for NMDA receptors  

International Nuclear Information System (INIS)

Aim: There has been a great demand for developments of the radioligands to visualize the N-methyl-D-aspartate (NMDA) receptors by PET/SPECT. We have recently synthesized two C-11 labeled antagonists for the glycine-binding site on NMDA receptors. The aim of this work is to examine for their in vitro and in vivo binding characteristics, and to evaluate their potentials as PET radioligands for the NMDA receptors. Materials and methods: Two C-11 labeled 4-hydroxy-2-quinolones (1 and 2) were synthesized by conventional methylation of the corresponding phenols with ["1"1C]methyl iodide. In vitro and ex vivo quantitative autoradiographs with imaging plate, as well as animal PET, were employed in order to evaluate their in vitro and in vivo binding to the NMDA receptors. Results: The compound 1 showed the specific binding to rat brain slices with higher localization in the hippocampus and cerebral cortex than in the cerebellum. ...

2002-09-01

438

Two-step template-free route for synthesis of TiO2 hollow spheres  

British Library Electronic Table of Contents (United Kingdom)

The TiO2 hollow microspheres were prepared by microwave-assisted solvothermal treatment without template. The morphology and the phase of TiO2 hollow microspheres were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), high resolution transmission electron microscopy (HR-TEM), and BET surface areas. The results show that the particles have hollow structures and the shell was covered by nanocrystals and have higher specific surface area. The possible formation mechanism of hollow TiO2 spherical structures has simply been proposed. The activity was evaluated by the photocatalytic degradation of methyl orange (MO). The results show that the particles having specific surface area show higher photocatalytic activity. It can be attribute to the doped ...

2011-01-01

439

Two dimensional NMR and NMR relaxation studies of coal structure  

Energy Technology Data Exchange (ETDEWEB)

This report covers the progress made on the title project for the project period. Four major areas of inquiry are being pursued. Advanced solid state NMR methods are being developed to assay the distribution of the various important functional groups that determine the reactivity of coals. Special attention is being paid to methods that are compatible with the very high magic angle sample spinning rates needed for operation at the high magnetic field strengths available today. Polarization inversion methods utilizing the difference in heat capacities of small groups of spins are particularly promising. Methods combining proton-proton spin diffusion with [sup 13]C CPMAS readout are being developed to determine the connectivity of functional groups in coals in a high sensitivity relay type of experiment. Additional work is aimed at delineating the role of methyl group rotation in the proton NMR relaxation behavior of coals.

1992-11-25

440

The separation of "2"0"3Pb from a thallium target  

International Nuclear Information System (INIS)

"2"0"3Pb, an ideal radionuclide for toxicological studies, can be artificially produced by bombardment of a thallium target but due to the extreme toxicity of thallium the lead has to be separated completely from the thallium. A single step method is here described consisting of removing the thallium from a dilute acid chloride solution using a continuous ethyl ether extraction. Essentially all of the thallium and almost none of the lead is removed in a 3-hr extraction. Because the ether is recycled, only about 30 ml are needed. If other contaminants are introduced from the bombardment and its subsequent manipulations, an additional step is used in which the lead is extracted from an iodide solution with methyl isopropyl keton. (U.K.).

441

Tertiary-Butanol: A toxicological review  

British Library Electronic Table of Contents (United Kingdom)

Tert-Butanol is an important intermediate in industrial chemical synthesis, particularly of fuel oxygenates. Human exposure to tert-butanol may occur following fuel oxygenate metabolism or biodegradation. It is poorly absorbed through skin, but is rapidly absorbed upon inhalation or ingestion and distributed to tissues throughout the body. Elimination from blood is slower and the half-life increases with dose. It is largely metabolised by oxidation via 2-methyl-1,2-propanediol to 2-hydroxyisobutyrate, the dominant urinary metabolites. Conjugations also occur and acetone may be found in urine at high doses. The single-dose systemic toxicity of tert-butanol is low, but it is irritant to skin and eyes; high oral doses produce ataxia and hypoactivity and repeated exposure can induce dependence...

2010-01-01

442

Targeting the kynurenine pathway as a potential strategy to prevent and treat Alzheimer's disease  

British Library Electronic Table of Contents (United Kingdom)

Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the elderly accounting for the vast majority of dementia. Recently, many studies have implicated the role of inflammatory response, especially neuroinflammatory response in the development and progression of AD. However, the underlying mechanism of how inflammatory response induces AD is unknown. Kynurenine pathway is a major route of the amino acid tryptophan catabolism, resulting in the production of nicotine adenine dinucleotide and other neuroactive intermediates: quinolinic acid (QA) and kynurenic acid (KA). QA exerts different toxic effects, including over-activation of N-methyl-d-aspartate (NMDA) receptor and excitotoxicity, synaptic dysfunction and neuronal death. On the other hand, KA is identified as the only...

2011-01-01

443

Synthesis of N-(3-azido-4-chlorophenyl)-N'-["3H-methyl] thiourea, an efficient photoaffinity probe for the urea carrier  

International Nuclear Information System (INIS)

Starting from commercial 4-chloro-3-nitroaniline, through a 5 step synthesis, 3-azido-4-chlorophenylisothiocyanate was prepared and reacted with ["3H]-methylamine. The latter was obtained by three methods: (i) ["3H]-LiA1T_4 reduction of benzylcarbamate gave rise to ["3H]-methylamine (S.A.: > 70 Ci/mmol). (ii) Catalytic reduction of HCN with "3H_2 lead to ["3H]-CH_3NH_2 (S.A.: 0.7 Ci/mmol). (III) Schmidt rearrangement of ["3H]-sodium acetate gave ["3H]-CH_3NH_2 (S.A.: 29 Ci/mmol). (author).

444

Synthesis and characterization of conducting polymer composite (PAn/TiO{sup 2}) for cathode material in rechargeable battery  

Energy Technology Data Exchange (ETDEWEB)

This paper deals with the preparation and characterization of polyaniline/TiO{sub 2} composite by XRD, UV-VIS spectra, TGA/DTA and FTIR. The composite is used as a cathode material for rechargeable battery comprising of zinc container as the anode, cellulose acetate as the separator and polyvinyl sulfate and carboxy methyl cellulose as the solid polymer electrolytes (SPE). By using the PAn/TiO{sub 2} composite as the cathode material, the cylindrical AA type rechargeable battery was fabricated and the following output was observed. The open circuit voltage (OCV) is 1.4 V and current is 250 mA to 1.0 A, 50 recharge cycles, power density is 350 A h/kg and power efficiency is 70%.

2003-02-01

445

Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases)  

British Library Electronic Table of Contents (United Kingdom)

Reactive blue 2 (RB-2) had been characterized as a relatively potent ectonucleoside triphosphate diphosphohydrolase (E-NTPDase) inhibitor with some selectivity for NTPDase3. In search for the pharmacophore and to analyze structure-activity relationships we synthesized a series of truncated derivatives and analogs of RB-2, including 1-amino-2-sulfo-4-ar(alk)ylaminoanthraquinones, 1-amino-2-methyl-4-arylaminoanthraquinones, 1-amino-4-bromoanthraquinone 2-sulfonic acid esters and sulfonamides, and bis-(1-amino-4-bromoanthraquinone) sulfonamides, and investigated them in preparations of rat NTPDase1, 2, and 3 using a capillary electrophoresis assay. Several 1-amino-2-sulfo-4-ar(alk)ylaminoanthraquinone derivatives inhibited E-NTPDases in a concentration-dependent manner. The 2-sulfonate group ...

2009-01-01

446

Structure and antimicrobial activity relationship of quaternary N-alkyl chitosan derivatives against some plant pathogens  

British Library Electronic Table of Contents (United Kingdom)

In the present work, quaternary chitosans as water-soluble compounds were prepared based on three-step process. Schiff bases were firstly synthesized by the reaction between the amino groups of chitosan with aliphatic aldehydes followed by a reduction with sodium borohydride (NaBH4) to form N-(alkyl) chitosans. N,N,N-(dimethyl alkyl) chitosans were then obtained by a reaction of chitosan containing N-butyl, N-pentyl, N-hexyl, N-heptyl, and N-octyl substituents with methyl iodide. The compounds were characterized using IR and NMR spectroscopy. Subsequent experiments were conducted to test their antimicrobial activities against the most economic plant pathogenic bacteria of crown gall disease Agrobacterium tumefaciens, soft mold disease Erwinia carotovora, fungi of grey mold Botrytis cinerea...

2010-01-01

447

Silica Polyamine Composites: New Supramolecular Materials for Cation and Anion Recovery and Remediation  

British Library Electronic Table of Contents (United Kingdom)

Summary: The surface coverage of amorphous silica gels used in the synthesis of silica polyamine composites has been investigated by 29Si NMR. By diluting the polyamine anchor silane, chloropropyl trichlorosilane, with methyl trichlorosilane it was found that surface coverage could be markedly improved for a range of amine polymers after grafting to the silica surface. The commensurate decrease in the number of anchor points and increase in the number of free amines results in an increase in metal capacity and/or an improvement in capture kinetics. Solid state CPMAS-13C NMR has been employed to investigate the structure and metal ion binding of a series of these composite materials. It is reported that the highly branched polymer, poly(ethyleneimine) (PEI) exhibits much broader 13C NMR res...

2006-01-01

448

Sheep prefer clean forage over forage contaminated with military explosives TNT, RDX and HMX  

British Library Electronic Table of Contents (United Kingdom)

The common military explosives 2-methyl-1,3,5-trinitrobenzene (TNT), 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) and 1,3,5,7-tetranitro-1,3,5,7-tetrazocane (HMX) are distributed in many military training areas, and are thus encountered by grazing animals. The aim of this study was to examine small ruminant's intake of forage contaminated with explosives. An indoor, experimental setup was used to determine if contamination of forage by these compounds affected intake by sheep. The results clearly demonstrate that contamination by any of the three explosives reduced forage intake in sheep; in order of increasing avoidance: RDX

2011-01-01

449

Resonance Raman and photophysical studies of transition metal complexes in solution and entrapped in zeolites  

Science.gov (United States)

We have obtained convincing evidence for localization of the optical electron on a single-ring fragment of a chelated bipyridine-like'' ligand (ie., pyridylpyrazine or 4-Methyl-bipyridine). In addition we have completed studies of Ru(bipyrazine){sub 3}{sup 2+} in aqueous sulfuric acid (0--98% by weight) and find clear evidence for sequential addition of six-protons to the six peripheral nitrogen atoms. Studies of zeolite-entrapped complexes are continuing and a series of homo- and heteroleptic complexes have been prepared and characterized. Finally, the synthesis of zeolite-entrapped metallophthalocyanines has now been developed and the copper and cobalt analogues synthesized. The characterization of these materials is now in progress.

1992-03-31

450

Research on the preparation of coal water fuel (CWF) from Banko coal, south Sumatera  

Energy Technology Data Exchange (ETDEWEB)

Studies of CWF preparation at laboratory scale have been carried out using the type and amount of additives and coal content as process variables. Other factors such as particle size, time and rate of stirring were kept constant. CWF with 45 wt% of dry solids, heating value of 5,475 BTU/lb, and stable without the evidence of sedimentation for 9 weeks have been obtained using carboxy methyl cellulose (CMC) as the additive. Low coal content and low heating value can be increased by hydrothermal process on the elevated temperature and pressure. By this process, CWF with dry solid of 55 wt% and a heating value of 7,125 BTU/lb could be obtained. 6 refs., 8 figs., 2 tabs.

1994-01-01

451

Preparation and photocatalytic property of pyrochlore Bi2Ti2O7 and (Bi, La) 2Ti2O7 films  

British Library Electronic Table of Contents (United Kingdom)

Dopant-free Bi2Ti2O7 thin films with pyrochlore structure and La-doped bismuth titanate thin films have been fabricated by means of chemical solution decomposition, and characterized by X-ray diffraction, atomic force microscopy, scanning electron microscopy and UV?Vis spectrophotometry in this study. Their photocatalytic activities have been evaluated by photodegrading methyl orange solution, and the optimum processing parameters for the highest photocatalytic activity have been found. Moreover, the effects of La-doping on the phase transformation and the photocalalytic activity have been studied. It has been deduced from the experiment result that substituted La3+ ions can act as a stabilizer of Aurivillus phase BLT and a grain?growth inhibitor in BLT thin films.

2008-01-01

452

Preparation and applications of wood-polyester composites  

International Nuclear Information System (INIS)

Optimum processing parameters were searched for the pilot-scale production of wood-polyester composites by irradiation of resin-impregnated wood material. The radiation initiation of the following systems were examined in wood and without wood matrix: methyl methacrylate, mixture of styrene and acrylonitryle, and their combination with unsaturated polyester. In the most cases the over-all rate of the complete polymerization process in wood matrix is proportional to the square root of the initiation rate. The parameters of the radiation technology of wood-polyester composites have been determined, using 260 TBq (7 kCi) "6"0Co radiation source. A pilot plant has been constructed using an underwater irradiation system of 1.85 PBq (50 kCi) "6"0Co. The successful production rate of 200 kg wood-polyester composite per day, as well as the application tests have demonstrated the technical feasibility of this new structural material. (author).

1982-01-01

453

Preparation and applications of novel fluoroalkyl end-capped vinyltrimethoxysilane oligomer/hydroxyapatite nanocomposites  

British Library Electronic Table of Contents (United Kingdom)

Novel fluoroalkyl end-capped vinyltrimethoxysilane oligomer/hydroxyapatite (HAp) nanocomposites were prepared by the reaction of calcium nitrate tetrahydrate and phosphoric acid in the presence of the corresponding oligomer. These fluorinated oligomer/HAp composites thus obtained are nanometer size-controlled fine particles (83-173 nm), and were found to exhibit good dispersibility in methanol, ethanol, and isopropyl alcohol. These fluorinated HAp nanocomposites were applied to the surface modification of glass and poly(methyl methacrylate) (PMMA) to exhibit good hydro- and oleophobic characteristics imparted by fluorine on their surface. In addition, the surface structural changes of the modified polyethylene terephtalate and PMMA films treated with these fluorinated nanocomposites before...

2009-01-01

454

Possible preparation of wood-plastic composites based on unsaturated polyester resins and styrene by radiation and chemical methods in combination  

Energy Technology Data Exchange (ETDEWEB)

Using the radiation chemical method it is possible to prepare wood-plastic composites using doses of 1 to 2.5 kGy. The impregnation mixture in the wood gelatinates and subsequent curing using chemical initiators takes place without outflow of the mixture from the wood and without formation of incrustations. The basic components of the impregnation mixtures used were unsaturated polyester resins; styrene or methyl methacrylate was used as the thinner. The proven initiator of polymerization was 2,2'-azobisisobutyronitrile. The technology is described of wood impregnation and radiation or chemical curing. The effects were monitored of viscosity, temperature, radiation dose and the concentrations of the individual components of the impregnation mixtures and initiators of polymerization on the process of the preparation of wood-plastic composites.

1983-06-01

455

Polymeric nanosponges as an alternative carrier for improved retention of econazole nitrate onto the skin through topical hydrogel formulation  

British Library Electronic Table of Contents (United Kingdom)

The present study was carried out to exploit the feasibility of using polymeric nanosponges as an alternative carrier for targeting econazole nitrate (EN) to the skin through topical hydrogel formulation. Nanosponges prepared by emulsion solvent diffusion method were evaluated for various physicochemical parameters and in vitro drug release. The nanosponges of EN were discrete free flowing nanosized particles with perforated orange peel like morphology as visualized by SEM. The nanosponge formulated using PVA:EC (3:2) displayed highest in vitro release after 12 ?h in phosphate buffer (pH 6.8) that fitted matrix model. Selected nanosponge was formulated as Carbopol 934 NF hydrogel using varying concentrations of permeation enhancers propylene glycol and N-methyl-2-pyrrolidone. The EN nanosp...

2011-01-01

456

Physical properties of wood-polymer composites prepared by an electron beam accelerator  

Energy Technology Data Exchange (ETDEWEB)

The dual characteristics in the performance of polymers in wood-polymer composites systems have been pursued with regard to the resolution of mechanical anisotropy of wood and the improvement in dimensional stability. The objective of the present study is to pursue the polymerization mechanism in wood under electron beam irradiation and the temperature dependence of polymer-wood interactions induced at various levels of higher order structure of wood in order to understand the polymer performance. Veneers used in the study were of rotary-cut beech (Fagus crenata Blume) 0.65 mm thick. All samples were oven-dried in vacuo at 80/sup 0/C for 30 hr. The monomers used in the study were methyl methacrylate, styrene, acrylic acid, acrylonitrile, and unsaturated polyester. Experimental details are given. Results are given and discussed.

1981-01-01

457

Photoelectron resonance capture ionization mass spectrometry of fatty acids in olive oil  

British Library Electronic Table of Contents (United Kingdom)

Photoelectron resonance capture ionization (PERCI) mass spectrometry has been developed for the direct online analysis of organics, including lipids. Analysis is conducted without the need for sample preparation or chemical derivatization such as methylation, foregoing the use of harmful or toxic chemicals. PERCI is currently being adapted towards the analysis of edible oils. Herein, as a proof of principle of the simplicity and potential utility of this method towards the analysis of edible oils, we present the analysis of the prevalent fatty acids (FA) in Tuscan extra-virgin olive oil along with triolein and linolenic acid (LNA) standards. Ionization of olive oil results in little fragmentation of the prevalent FA, which are measured as their molecular ions, [FA-H]-. The relative concent...

2006-01-01

458

One-electron redox reactions of pyrazolin-5-ones. A pulse radiolysis study of antipyrine and analogues  

Energy Technology Data Exchange (ETDEWEB)

One-electron oxidation of several derivatives of pyrazolin-5-one, including the drug antipyrine, were studied by pulse radiolysis of aqueous solutions. All the compounds were found to be oxidized by Br2 rapidly but considerably more slowly by weaker oxidants, such as peroxyl radicals. From redox equilibria using p-methoxyphenol and N,N,N',N'-tetramethyl-p-phenylenediamine as reference compounds, the one-electron oxidation potentials of the methyl-substituted 2-pyrazolin-5-ones were found to be in the range of 0.32-0.39 V versus normal hydrogen electrode. The relevance of these findings to the properties of the drug nafazatrom is discussed. Antipyrine was found to have a much higher oxidation potential, estimated as 1.2-1.5 V, which is rationalized on the basis of the phenyl substitution and lack of resonance stabilization of the radical cation.

1985-10-01

459

On synergism in inhibition of liquidphase oxidation of styrene and tetralin by organic phosphites and transition eleement acetylacetonates  

International Nuclear Information System (INIS)

Synergism has been observed during inhibiting initiated oxidation of styrene or tetralin by organic phosphites in the presence of complex compounds of some transition metals. The results are given of non-additive intensification of antioxidative activity of triphenylphosphite (TPP) and tri-(4-methyl-6-tert.-- butyl)-phenyl-phosphite (TMBP) in the process of initiated oxidation of styrene or tetralin with addition of acetylacetonates of cobalt and vanadyl. During styrene oxidation, inhibition of the reaction with chelate complex of vanadyl is weakened considerably when phosphite is added into the reaction system. During tetralin oxidation, postcatalytic (or branched) oxidation is observed only for large concentration of vanadyl complex. Addition of TPP to above complex sharply increases the induction period. When the induction period is completed, oxidation of tetralin follows the mechanism of usual, i.e. initiated, reaction.

460

Molecular marks for epigenetic identification of developmental and cancer stem cells  

British Library Electronic Table of Contents (United Kingdom)

Epigenetic regulations of genes by reversible methylation of DNA (at the carbon-5 of cytosine) and numerous reversible modifications of histones play important roles in normal physiology and development, and epigenetic deregulations are associated with developmental disorders and various disease states, including cancer. Stem cells have the capacity to self-renew indefinitely. Similar to stem cells, some malignant cells have the capacity to divide indefinitely and are referred to as cancer stem cells. In recent times, direct correlation between epigenetic modifications and reprogramming of stem cell and cancer stem cell is emerging. Major discoveries were made with investigations on reprogramming gene products, also known as master regulators of totipotency and inducer of pluoripotency, na...

2011-01-01

461

Jump in the air gasification rate of potassium-doped cellulosic chars  

Energy Technology Data Exchange (ETDEWEB)

Chars prepared from potassium-exchanged carboxy methyl cellulose at several heat treatment temperatures (HTTs) were gasified in air isothermally at selected gasification temperatures (GTs) in the range 633-893 K to investigate the catalytic effectiveness of potassium species. The chars displayed a noticeable jump in gasification rate at a particular gasification temperature (called jump temperature, T{sub j}). The magnitude of jump was much less than that reported for copper and nickel catalysis, but comparable with that for calcium catalysis. Increase in HTT caused a decrease in the jump temperature of chars in contrast with the increase observed in copper, nickel and calcium catalysis; also the magnitude of jump did not decrease, but remained unaltered, on increasing HTT. The different behavior of potassium catalysis is correlated to a change in the chemical state of potassium at higher HTT. The results reveal the dependence of jump phenomenon on chemical state ...

2010-12-15

462

Ionically conductive thin polymer films prepared by plasma polymerization. Pt. 7. Preparation and characterization of solid polymer electrolyte having fixed carboxylic acid groups with single mobile species  

Energy Technology Data Exchange (ETDEWEB)

Ultra-thin, uniform, pinhole-free solid polymer electrolyte films having a fixed carboxylic ester group of approximately 1 {mu}m thickness were prepared by polymerization of methyl acrylate and tris(2-methoxyethoxy)vinylsilane in a glow discharge plasma. The carboxylic ester group of the plasma polymer were transformed to lithium carboxylate groups by treatment with lithium iodide. This process give a single lithium ion conductive film. These solid polymer electrolyte films showed ionic conductivities of the order of 10{sup -8} S cm{sup -1} (10{sup 4} {omega} cm{sup 2} resistance per unit area) at room temperature. (orig.).

1990-08-01

463

Ionically conductive thin polymer films prepared by plasma polymerization  

International Nuclear Information System (INIS)

Ultrathin solid polymer electrolyte membranes containing sulfonic ester groups were prepared by polymerization of methyl benzenesulfonate and octamethylcyclotetrasiloxane in a glow discharge plasma. The sulfonic ester groups of the plasma polymer were transformed to lithium sulfonate groups by treatment with lithium iodide. Hybridization of this plasma polymer containing the lithium sulfonate groups with poly(ethylene oxide) (average Mw 300) resulted in the formation of a single lithium ion conductive film. The hybrid polymer electrolyte films were about 1 #mu#m thick, pinhole-free, adherent to various substrates, and showed ionic conductivities at 60 degrees C of the order of 10"- "6 S cm"- "1 (10"2 #OMEGA# cm"2 resistance per unit area of as-prepared solid polymer electrolyte). This material shows promise for electrochemical applications such as all solid-state lithium batteries, sensors, and electrochemical display devices.

464

Imaging hypoxia in vivo by controlling the electrochemistry of copper radionuclide complexes  

British Library Electronic Table of Contents (United Kingdom)

Tissue hypoxia is a feature of cancer, heart disease and stroke, and imaging it may become clinically important. Copper-ATSM (ATSMH2 = 2,3-butanedione bis(N-methyl)thiosemicarb-azone), labelled with 60Cu, 62Cu or 64Cu, is selectively taken up in hypoxic cells in vitro and in vivo by a bioreductive mechanism, and is a prototype hypoxia imaging agent amenable to improvement. In vitro studies with several differently alkylated analogues of CuATSM show that hypoxia selectivity is a general property of complexes with two alkyl groups at the diketone backbone, offering a range of pharmacokinetic properties while retaining hypoxia selectivity. This pharmacokinetic control affords a route to development of second-generation hypoxia imaging agents with optimized properties for different clinical ap...

2007-01-01

465

Hepatitis C virus core upregulates the methylation status of the RASSF1A promoter through regulation of SMYD3 in hilar cholangiocarcinoma cells  

British Library Electronic Table of Contents (United Kingdom)

Increasing evidence has been accumulated indicating the important role of epigenetic regulation in tumor genesis. Previously, we observed that the transfection of hepatitis C virus core (HCVc) protein led to malignant transformation in normal biliary cells, and that tumor suppressor gene RASSF1A was downregulated in many hilar cholangiocarcinoma patients by hypermethylation in the promoter region. In the present study, we found SET and MYND domain-containing protein 3 (SMYD3), a novel histone methyltransferase, was overexpressed in cholangiocarcinoma patients especially in those with HCV infection. Transfection of HCVc into hilar cholangiocarcinoma cell lines QBC939 and FRH0201 could upregulate the expression of SMYD3 and promote cell growth, which was consistent with the results of our cl...

2011-01-01

466

Heat capacities of the mixtures of ionic liquids with acetonitrile  

International Nuclear Information System (INIS)

Isobaric specific heat capacities were measured for {1-hexyl-3-methylimidazolium tetrafluoroborate (HMIMBF4) + acetonitrile (MeCN)} and {1-methyl-3-octylimidazolium tetrafluoroborate (OMIMBF4) + acetonitrile} within the whole range of composition and temperatures from (283.15 to 323.15) K. The excess molar heat capacities were calculated from the experimental results and satisfactorily fitted to Redlich-Kister type polynomials for several selected temperatures. Negative deviations from the additivity of molar heat capacities were observed within the whole composition range of (HMIBMF4 + MeCN) and (OMIMBF4 + MeCN). The results obtained have been interpreted in terms of interactions between ionic liquids and acetonitrile.

2010-02-01

467

Green synthesis of iron nanoparticles and their application as a Fenton-like catalyst for the degradation of aqueous cationic and anionic dyes  

British Library Electronic Table of Contents (United Kingdom)

Iron nanoparticles were produced using extracts of green tea leaves (GT-Fe NPs). The materials were characterized using TEM, SEM/EDX, XPS, XRD, and FTIR techniques and were shown to contain mainly iron oxide and iron oxohydroxide. The obtained nanoparticles were then utilized as a Fenton-like catalyst for decolorization of aqueous solutions containing methylene blue (MB) and methyl orange (MO) dyes. The related experiments investigated the removal kinetics and the effect of concentration for both MB and MO. The concentrations of dyes in aqueous solution were monitored using ultraviolet-visible (UV-vis) spectroscopy. The results indicated fast removal of the dyes with the kinetic data of MB following a second order removal rate, while those of MO were closer to a first order removal rate. T...

2011-01-01

468

Global status of commercialization of and developments on international trade in irradiated food  

Science.gov (United States)

National and international organizations have paid particular attention to the use of food irradiation as a method to reduce postharvest food losses, to ensure hygienic quality of foods-especially those of animal origin, and to overcome certain non-tariff barriers to trade for the following reasons: (1) The increasingly strict standards for quality and quarantine in food trade. (2) The increasingly restrictions and prohibitions of fumigants of food for health or environmental reasons. (3) The increasing awareness of foodborne diseases in both advanced and developing countries. (4) The high postharvest losses of foods in developing countries. (5) The increase liberalization of food trade after GATT Uruguay Round, and the need to maintain or increase export of food and agricultural commodities and to be competitive in the world market. Irradiated foods have been commercialized since 1973 when the first potato irradiator was established at the Shihoro Agricultural Cooperative, Hokkaido, ...

1996-09-01

469

Flavonols and an oxychromonol from Piliostigma reticulatum  

British Library Electronic Table of Contents (United Kingdom)

The leaf extract from the plant Piliostigma reticulatum was found to exhibit antimicrobial activity against some bacteria and fungi such as Staphylococcus aureus (NCTC 6571), Escherichia coli (NCTC 10418), Bacillus subtilis (NCTC 8236), Proteus vulgaris (NCTC 4175), Aspergillus niger (ATCC 10578) and Candida albicans (ATCC 10231). Upon investigation of the chemical constituents present in the leaf extract, a total of seven compounds were isolated and their structures were unambiguously established by spectroscopic methods including HR-MS and NMR spectrometry. Four of the isolated compounds were novel, namely 6-C-methyl-2-p-hydroxyphenyloxychromonol (piliostigmol), 1, 6,8-di-C-methylquercetin-3,3prime,7-trimethyl ether, 2, 6,8-di-C-methylquercetin-3,3prime-dimethyl ether, 3 and 3prime,6,8,-...

2008-01-01

470

Facilitated Proton Transfer by a Novel 2-Aminothiazole Derivative Across the Water/1,2-Dichloroethane Interface  

British Library Electronic Table of Contents (United Kingdom)

The behavior of proton transfer facilitated by a novel thiazole derivative, N-methyl-4-(4-phenoxyphenyl)thiazol-2-amine (MPPT), across the water/1,2-dichloroethane (1,2-DCE) interface was investigated electrochemically. The ionic partition diagram for MPPT was obtained from interpretation of the cyclic voltammograms. The apparent partition coefficient of MPPT was evaluated by the shaking-flask method under experimental conditions, while that for the protonated form of MPPT was calculated from its transfer potential obtained from the ionic partition diagram. It was suggested that the mechanism for transfer of MPPT across the water/1,2-DCE) interface depends on the pH of the aqueous phase. The parameters of the facilitated proton transfer across the water/1,2-DCE interface were evaluated as ...

2011-01-01

471

Exploring the potential energy surface for proton transfer in acetylacetone  

Energy Technology Data Exchange (ETDEWEB)

The portion of the potential energy surface (PES) of acetylacetone relevant for the intramolecular proton transfer reaction is studied using ab initio and DFT methods. The best estimate of the barrier governing proton transfer was found to be 3.4 kcal mol{sup -1} at the MP4(FC)/6-311 + G(2d,2p)//MP2(FC)/6-311 + G(2d,2p) level of theory. Six stationary points on the PES were characterized as well as the reaction paths connecting these points. Special attention paid to the pathway of intramolecular proton transfer reveals that the internal rotation of the methyl group adjacent to the carbonyl group and the proton transfer reaction are consecutive processes.

2004-11-15

472

Excess and deviation properties for the binary mixtures of methylcyclohexane with benzene, toluene, p-xylene, mesitylene, and anisole at T = (298.15, 303.15, and 308.15) K  

International Nuclear Information System (INIS)

Experimental data on density, viscosity, and refractive index at T = (298.15, 303.15, and 308.15) K, while speed of sound values at T = 298.15 K are presented for the binary mixtures of (methylcyclohexane + benzene), methylbenzene (toluene), 1,4-dimethylbenzene (p-xylene), 1,3,5-trimethylbenzene (mesitylene), and methoxybenzene (anisole). From these data of density, viscosity, and refractive index, the excess molar volume, the deviations in viscosity, molar refraction, speed of sound, and isentropic compressibility have been calculated. The computed values have been fitted to Redlich-Kister polynomial equation to derive the coefficients and estimate the standard errors. Variations in the calculated excess quantities for these mixtures have been studied in terms of molecular interactions between the component liquids and the effects of methyl and methoxy group substitution on benzene ring.

2006-12-01

473

Estimation of dietary intake of ochratoxin A from liquorice confectionery  

British Library Electronic Table of Contents (United Kingdom)

Ochratoxin A (OTA) was analyzed from 44 liquorice confectionery samples using immunoaffinity cleanup and liquid chromatography coupled with fluorescence detection. The presence of OTA was confirmed by methyl-ester derivatization. Liquorice confectionery samples were purchased from different retail outlets and supermarkets in Spain during 2007-2008, 16 of hard candies and 28 of soft candies. The incidence of OTA varied between 75% and 39% and mean ranged from 2.96 to 0.34mg/kg for hard and soft candies, respectively. Assuming a total mean value of 1.29mgOTA/kg sweet and a consumption of about 1.2g liquorice sweets per day, an OTA weekly uptake of 11ng was obtained, or, based on a total body weight of 30kg for a child consuming these sweets regularly, a weekly intake of 0.37ng/kg body weight...

2009-01-01

474

Electrochemical impedance of electrolyte/electrode interfaces of lithium-ion rechargeable batteries  

Energy Technology Data Exchange (ETDEWEB)

It is well known that a protective film is formed on the graphite negative electrode in ethylene carbonate (EC) electrolyte solution. This film is lithium-ion conductive and protects the decomposition of the electrolyte solution. In the present paper, the electrode/electrolyte interfaces in lithium-ion rechargeable batteries were characterized by three-dimensional complex impedance plots, whose axes are real, imaginary parts and time. The film resistance R {sub sei} and charge transfer resistance R {sub ct} were determined for negative electrodes in EC/ethyl methyl carbonate (EMC) electrolyte solution, and the formation mechanisms of the interfacial film were discussed. Furthermore, the contributions of vinylene carbonate and ethylene sulfite, which are added into the electrolyte solution for the film formation, were investigated.

2006-01-20

475

Electrochemical impedance of electrolyte/electrode interfaces of lithium-ion rechargeable batteries  

International Nuclear Information System (INIS)

It is well known that a protective film is formed on the graphite negative electrode in ethylene carbonate (EC) electrolyte solution. This film is lithium-ion conductive and protects the decomposition of the electrolyte solution. In the present paper, the electrode/electrolyte interfaces in lithium-ion rechargeable batteries were characterized by three-dimensional complex impedance plots, whose axes are real, imaginary parts and time. The film resistance R _s_e_i and charge transfer resistance R _c_t were determined for negative electrodes in EC/ethyl methyl carbonate (EMC) electrolyte solution, and the formation mechanisms of the interfacial film were discussed. Furthermore, the contributions of vinylene carbonate and ethylene sulfite, which are added into the electrolyte solution for the film formation, were investigated.

2006-01-20

476

Determination of some minor and trace elements in iron ores by ion exchange chromatography, spectrophotometry and atomic absorption spectrometry  

International Nuclear Information System (INIS)

A method is described for determination of aluminium, cadmium, cobalt, chromium, copper, calcium, magnesium, sodium, potassium, manganese, nickel, lead, strontium, zinc, titanium and vanadium in iron ore. After dissolution, a 1 gram sample of iron ore is applied to a column of AGI-X8 anion exchange resin (chloride form), in 100 ml of 7M HCl. Aluminium, chromium, calcium, magnesium, sodium, potassium, manganese, nickel, lead, strontium, titanium and vanadium are eluted with 7M HCl; iron, copper and cobalt are eluted with 0.5M HCl; cadmium and zinc are eluted with 2M HNO_3. Iron is subsequently removed from copper and cobalt by a solvent extraction with methyl isobutyl ketone. The elements are determined in the eluates by atomic absorption spectrometry, except for titanium and vanadium, which are determined spectrophotometrically.

477

Creep-characteristics of a tropical wood-polymer composite  

Energy Technology Data Exchange (ETDEWEB)

Wood polymer composite (WPC) specimens were produced by impregnating a tropical wood with methyl methacrylate and subsequently polymerised by ..gamma..-irradiation. Beam specimens of varying weight percentages of polymer were then subjected to a three point bend creep test under a constant load condition, for 250, 300 and 350 N. A Norton-Bailey (power law) mathematical model was used to describe the creep behavior, with the creep components determined by a nonlinear regression analysis. Significant creep improvements were obtained from the composite specimens as compared to the untreated wood specimens. Results indicated that maximum creep resistance is obtained when the amount of polymer loading exceeded 30%. An interfacial interaction between the polymer and the wood cell wall was used to account for the behavior of the increase in the creep resistance.

1987-01-01

478

Covalent modification of fused silica capillaries with quaternized polyamines to achieve robust and stable anodic electroosmotic flow  

British Library Electronic Table of Contents (United Kingdom)

Synthetic chemistry originally developed for the manufacture of chemically stable silica polyamine composites was adapted for the modification of fused silica capillaries for application in CE. Polyethyleneimine (PEI) and polyallylamine (PAA) were covalently bonded to the interior surface of fused silica capillaries utilizing 3-chloropropyltrichlorosilane (CPTCS) or 3-glycidoxypropyl-trimethoxysilane (GPTMS) to anchor the polymers to the surface. The surface-bound polymers were subsequently quaternized using methyl iodide (MeI). The resulting modified capillaries were studied using CE, and were shown to provide reproducible, stable, and robust anodic EOF throughout the pH range of 2-10. Surface modifications utilizing CPTCS could be rinsed with up to 6 M HCL or 1 M NaOH without significant...

2009-01-01

479

Cleanliness of small precision swabs  

Energy Technology Data Exchange (ETDEWEB)

Small swabs are often dampened with a solvent when used to clean surfaces. Cotton swabs of the type sold in drug stores contain stearic acid, probably used as a lubricant during manufacture of the swab. Such swabs, dampened with a solvent and used to clean a surface, will leave a film of stearic acid on the surface. Several kinds of swabs are sold for industrial use, and some are described as suitable for use in clean room manufacturing. Nine different swabs, some cotton and some urethane foam, were extracted with isopropyl alcohol, CFC 113 (Freon TF or Genesolv D), or mixture of CFC 113 and methyl alcohol. After evaporation of the solvent, from 0.5 to 3.8 mg of an oil or grease remained. For critical applications, swabs should be washed with solvent before use.

1992-02-01

480

Chemical constituents of Galianthe brasiliensis (Spreng.) E.L.Cabral and Bacigalupo (Rubiaceae); Constituintes quimicos de Galianthe brasiliensis (Rubiaceae)  

Energy Technology Data Exchange (ETDEWEB)

The paper describes the chemical constituents isolated from aerial parts of the plant Galianthe brasiliensis. From a methanol extract, the iridoid glycosides asperuloside, deacetylasperuloside, mixture of Z- and E-6-O-p-coumaroylscandoside methyl ester, the triterpene ursolic acid and the steroids stigmasterol, campesterol, b-sitosterol and 3-O-b-glucopyranosyl sitosterol were isolated. The structures of the natural products were identified on the basis of spectral data, including 2D NMR experiments. The antiproliferative properties of the crude methanolic extract were investigated against a series of nine human cancer cell lines. (author)

2006-05-15

481

Carnation Fusarium wilt suppression in four composts  

British Library Electronic Table of Contents (United Kingdom)

Fusarium wilt is now a major disease of carnation crops worldwide. Methyl bromide, which is used to remedy it, is environmentally unsafe. An alternative approach integrated into biological control is to grow crops in suppressive media. Suppressiveness of seven plant growth media to Fusarium oxysporum f. sp. dianthi was evaluated in bioassays with carnation (Dianthus cariophyllus) cv. Medea. These media were: (1) grape marc compost, (2) cork compost, (3) olive oil husk + cotton gin trash composted and mixed with rice husk, (4) spent mushroom compost mixed with peat, (5) coir fibre, (6) light peat and (7) vermiculite. In order to look for carnation Fusarium wilt suppressiveness indicators, growth medium pH and ?-glucosidase activity were evaluated. Furthermore, F. oxysporum populations were ...

2009-01-01

482

Tachyons and magnetic monopoles in the De Sitter universe  

International Nuclear Information System (INIS)

The author examines the place of tachyons and magnetic monopoles in the 'projective relativity' theory, which is based on the De Sitter universe and which has special relativity as a limiting case. A link with a generalized form of Maxwell's equations is examined in detail, the connection being through the rotation group R_5. (W.D.L.).

483

Slurry intake device  

Energy Technology Data Exchange (ETDEWEB)

A slurry intake device is proposed which contains an inlet sleeve, housing with grating installed with the discharge end in the zone of the slurry outlet, and hinged deflector. In order to conserve the clay mud, it is equipped with a tie rod and two-arm lever which is kinematically linked to the deflector and the grating. It is installed by hinges in relation to the housing and the latter is attached by hinges to the inlet sleeve. The deflector is arranged in the zone of slurry outlet. The device is distinguished by the fact that the deflector is equipped with a cantilever on which a fixable weight is attached.

1982-01-01

484

Serum Globotriaosylceramide Assay as a Screening Test for Fabry Disease in Patients with ESRD on Maintenance Dialysis in Korea  

UK PubMed Central (United Kingdom)

Background/AimsFabry disease is an X-linked recessive and progressive disease caused by α-galactosidase A (α-GaL A) deficiency. We sought to assess the prevalence...Full Text Available

2010-12-01

485

Religious groups have too much freedom to discriminate | Evan Harris | Comment is free | guardian.co.uk  

Wastenet

... Wanting to help a charity is commendable but the main focus of generosity should be the people in front of you, not your choice of spiritual overlord - especially so if the group is being funded with money from taxpayers. Recommend? (44) Report abuse | Link ...

486

Reconnaissance technique for radon risk classification of foundation soils  

Energy Technology Data Exchange (ETDEWEB)

Infiltration of radon from the ground is usually the primary source of indoor radon pollution. A uniform method for radon risk classification of foundation soils based on soil-gas radon concentration measurements and on the determination of soil porosity, permeability and structure was proposed in 1990. Results of assessment of some areas in Czechoslovakia, containing more than 5000 radon concentration measurements, demonstrate the utility of the technique and confirm the link between geology and radon potential of the soil. (author)

1992-07-01

487

Radiation hardening of optical fiber links by photobleaching with light of shorter wavelength  

International Nuclear Information System (INIS)

The influence of additionally injected short-wavelength photobleaching light on the radiation hardness of Ge-doped graded index fibers working at 1,300 nm wavelength is investigated. Predictions are complicated by the fact that more efficient shortwave bleaching light experiences higher radiation-induced loss. Promising results are found for low fiber temperatures (approx-lt -50 C) and bleaching light of about 835 nm wavelength.

1995-09-18

488

Preparation and Characterization of Fe3O4/CdTe Magnetic/Fluorescent Nanocomposites and their Applications in Immuno-labeling and Fluorescent Imaging of Cancer Cells  

UK PubMed Central (United Kingdom)

The synthesis of a new kind of magnetic, fluorescent multifunctional nanoparticles (~30 nm in diameter) was demonstrated, where multiple fluorescent CdTe quantum dots (QDs) are covalently linked...Full Text Available

2010-01-19

489

Possible stellar evolutionary link to black holes  

Science.gov (United States)

The suggestion has been made that stars with collapsing iron cores may be unable to explode, and hence may generate black holes. The situation when the collapsing core is rotating and magnetized is investigated and it is tentatively concluded that these effects make the situation even more conducive to the formation of black holes. (auth)

1973-10-01

490

Pathways to equity in mathematics education: how life experiences impact researcher positionality  

British Library Electronic Table of Contents (United Kingdom)

This study examined the life histories of a group of emerging scholars in the field of mathematics education who identify themselves as having a particular interest in and concern for issues of equity and diversity. Experiences of being the "other," "bearing witness" to "othering experiences," and "orienting experiences" in relation to issues of equity proved to be prominent themes in participants' life histories. These experiences were then linked to the positionality that these scholars now have in relation to their research in mathematics education.

2011-01-01

491

Improvement in loosening equipment  

Energy Technology Data Exchange (ETDEWEB)

The loosening equipment consists of a base machine and four-link suspension mechanism which is a cross frame with loosening gear connected to the base machine by universal hinges. In order to improve the reliability of the machine, the drive of transverse shifting in the cross frame is made of symmetrically arranged, shock-absorbing, hydraulic cylinders which are connected by additional universal hinges to the base machine and the lower pull rods. The design of the loosening machine guarantees its reliable operation on soil with significant quantity of hard inclusions.

1982-01-01

492

Improved control of fuel crushing in coal-fired power stations  

Energy Technology Data Exchange (ETDEWEB)

With the frequent load changes to which a hard coal power station is subjected in the middle and peak load range, great demands are linked with the transient behaviour of the steam generator. Due to the serial connection of the crusher and boiler, the strongly delaying transient behaviour of the crusher compounds entirely with the transient behaviour of the steam generator. Therefore, a suggestion is to be made here as to the improvement of the dynamics of the crusher.

1988-01-01

493

Evaluating and improving the operating reliability of the units of sucker rod well pumps  

Energy Technology Data Exchange (ETDEWEB)

The theory of reliability is used to develop statistical field data on malfunctions of units of sucker rod well pumps (UShSN). The indices of reliability of the UShSN are applied for establishment of the cause-effect links between the operating factors. Dependences of operating time on the depth of suspension of the pumps, mode of pumping out, degree of flooding of the oil, and twisting of the shafts are established for conditions of specific fields. The obtained relationships can be used in selecting and optimizing the work of the UShSN.

1982-01-01

494

Effects of Short-Term Treadmill Exercise Training or Growth Hormone Supplementation on Diastolic Function and Exercise Tolerance in Old Rats  

UK PubMed Central (United Kingdom)

Whether the lusitropic potential of short-term exercise in aged rats is linked to an augmentation in the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and an alteration in the...Full Text Available

2008-09-01

495

Effective fracture toughness of microcracked materials  

Energy Technology Data Exchange (ETDEWEB)

Explicit analytical formulas are derived for the stress intensity factors at the tips of a main crack and of a microcrack for the two-dimensional case of a collinear microcrack. This configuration is used to derive an estimate of the toughness degradation due to microcracks linking up with an advancing main crack. The implications of this estimate for theoretical predictions of the toughening due to stress-induced microcracking are discussed.

1986-03-01

496

EcoEarth.Info Environment Links: Ocean/Information  

Wastenet

... 01, 2009 | Rate It Marine Technology Society https://www.mtsociety.org/home.aspx emphasizes the importance of marine technology as it applies to global issues, encourages marine technology education and facilitates the use of marine technology in managing marine resources Added: Mar. 11, 2010 |...

497

Development of species-specific enzyme-linked immunosorbent assay for diagnosis of Johne's disease in cattle.  

UK PubMed Central (United Kingdom)

The previously described (M. De Kesel, P. Gilot, M.-C. Misonne, M. Coene, and C. Cocito, J. Clin. Microbiol., 31:947-954, 1993) a362 recombinant polypeptide of Mycobacterium paratuberculosis was used...Full Text Available

1994-05-01

498

Conservation of B class gene expression in the second whorl of a basal grass and outgroups links the origin of lodicules and petals  

UK PubMed Central (United Kingdom)

Studies of flower development in core eudicot species have established a central role for B class MADS-box genes in specifying petal and stamen identities. Similarly in maize and rice, B class genes...Full Text Available

2007-01-16

499

Assimilation of Remote Sensing Data into Shelf Sea Hydrodynamic Models  

Environmental Research Database

DescriptionRemote sensing of the sea surface from satellites in near-polar orbits has contributed greatly to our understanding of the links between physical and biological processes in marine systems. However most of this progress has been made in open oceanic waters or major upwelling areas, and many unresolved problems are encountered in coastal regions and shelf seas. In these optically complex waters, quantitative remote sensing requires a more sophisticated interpretation strategy than that implemente [continued...