h1n1v vaccine development: Topics by WorldWideScience.org

Advances in molecular biology: impact on rotavirus vaccine development.

Development of the Culture Influenza Vaccine

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Safety and immunogenicity of a vaccine bait containing ERA strain of attenuated rabies virus.

The first candidate rotavirus vaccine was a live attenuated oral vaccine made by the classical empirical method of serial passage of virus in tissue culture cells. Current tetravalent vaccine candidates that are in the final stages of efficacy testing in the United States were made by genetic reassortment. This article briefly highlights how advances in the basic understanding of the molecular biology of rotaviruses have facilitated vaccine development. New approaches for second-generation vaccines and improvements in vaccine efficacy based on further exploitation of the tools and knowledge of rotavirus molecular biology and pathogenesis are discussed. PMID:8752289

1996-09-01

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Isolation and Identification of Mycoplasmas

Ninety percent of foxes fed commercial ERA vaccine in a specially designed bait developed rabies serum neutralizing antibodies. The vaccine bait did not cause clinical signs of rabies when consumed...Full Text Available

1987-10-01

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The influence of MHC polymorphism on the selection of T-cell determinants of FMDV in cattle.

Isolation and Identification of Mycoplasmas, Development of Reliable Antigen for Mycoplasmas Detection and Oil-Based Vaccines

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Synchronous infection of SIV and HIV in vitro for virology, immunology, and vaccine-related studies

There is a quest for the development of a new generation of vaccines consisting of well-defined subunit antigens. For a number of practical reasons it is attractive to develop vaccines on the basis...Full Text Available

1995-01-01

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Current status of a hepatitis C vaccine: encouraging results but significant challenges ahead

The development of an HIV vaccine will require a more precise understanding of the immunological and virological underpinnings of HIV infection. Magnetofection, the process of magnetizing HIV...Full Text Available

2010-01-01

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T Cell Responses to the RTS,S/AS01_E and RTS,S/AS02_D Malaria Candidate Vaccines Administered According to Different Schedules to Ghanaian Children

Persistent hepatitis C virus (HCV) infection affects 170 million people worldwide. Acute HCV infection is often asymptomatic, but many infected individuals develop persistent infections that may lead to development of end-stage liver diseases, including liver cirrhosis and hepatocellular carcinoma. Thus, an HCV vaccine that could significantly lower the chronicity rate would have a major impact on the disease burden. Unfortunately, HCV is a highly mutable virus, and escape mutations can undermine vaccine-induced virus-specific immunity. Also, HCV exists as multiple genotypes, and so genotype-specific vaccines might be required to achieve broad protection. Finally, vaccine development has been hampered by the lack of a small animal model and cell culture systems, but these are currently being established. Despite these obstacles, several ...

2007-01-01

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BackgroundThe Plasmodium falciparum pre-erythrocytic stage candidate vaccine RTS,S is being developed for protection of young children against...Full Text Available

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Targeting vaccines to dendritic cells

...INFORMATION Diarrhoeal disease Food safety and foodborne illness Enterohaemorrhagic Escherichia coli (EHEC) Cholera WHO PROGRAMMES AND ACTIVITIES Child and Adolescent Health and Development (...FOS) Initiative for Vaccine Research (IVR) TECHNICAL INFORMATION Vaccine research: diarrhoeal diseases Cholera Water-related diseases Household water treatment and safe storage WHO Global Salm-Surv ...PUBLICATIONS Diarrhoea: child and adolescent health Diarrhoea: cholera RELATED TOPICS - Child health - Water - Food safety - Cholera - Travel - Breastfeeding ...

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Malnutrition, Gut-Microbial Interactions and Mucosal Immunity to Vaccines, 07 Nov 2011 - 11 Nov 2011, Le Meridien New Delhi, New Delhi, India - SciDe

Udgivelsesdato: 2002-Mar

2002-01-01

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Syndecan-Fc Hybrid Molecule as a Potent In Vitro Microbicidal Anti-HIV-1 Agent?

... A better understanding of the links between nutrients, the gut microbiome and the intestinal immune system is likely to pave the way to the development of innovative approaches that target activation of specific immunological pathways for promoting the hostrsquo;s gut defense. Such knowledge should positively impact on the development of vaccine formulations and intervention strategies for improved control of enteric infections in developing countries. Registration fees # The Registration Fee is $715.00 on and before September 7, 2011. # After September 7, 2011, the ...

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Regulatory compliance | Mott MacDonald

In the absence of a vaccine, there is an urgent need for the development of safe and effective topical microbicides to prevent the sexual transmission of human immunodeficiency virus type 1 (HIV-1)....Full Text Available

2010-07-01

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Peru-15, an improved live attenuated oral vaccine candidate for Vibrio cholerae O1.

...broad range of experience in designing and building research and development laboratories for products such as vaccines, blood and sera, biological products, medical devices, solid dosage forms , highly potent products and cytotoxic material. We also have experience in a range of modular laboratories for TSE research, ...

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Immunization of foxes by the intestinal route using an inactivated rabies vaccine.

Cholera vaccine candidate Peru-15 was derived from a Vibrio cholerae O1 El Tor Inaba strain by deleting the cholera toxin genetic element, introducing the gene encoding cholera toxin B subunit into recA, and screening for nonmotility. In a controlled study, Peru-15 (2 x 10(8) cfu) was administered to 11 volunteers. No vaccinee developed diarrhea, and 10 of 11 had > 4-fold rises in vibriocidal antibody titers. One month later, 5 vaccinees and 5 control volunteers were challenged with wild type V. cholerae O1. Four of 5 controls developed diarrhea (mean, 1.9 L). Two Peru-15 vaccinees developed diarrhea, 1 with < 0.3 L and 1 with approximately 1.0 L; this latter volunteer had not developed a significant vibriocidal immune response to vaccination. Peru-15 shows promise as a single-dose, oral cholera vaccine that is safe, immunogenic, and ...

1995-10-01

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Emulsified Nanoparticles Containing Inactivated Influenza Virus and CpG Oligodeoxynucleotides Critically Influences the Host Immune Responses in Mice

Approximately 30% of foxes given two doses of an inactivated rabies antigen delivered directly into the intestinal tract developed an immune response as measured by rabies serum neutralizing antibodies....Full Text Available

1989-01-01

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Dengue virus-specific murine T-lymphocyte proliferation: serotype specificity and response to recombinant viral proteins.

BackgroundAntigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy...Full Text Available

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Dengue virus protein recognition by virus-specific murine CD8+ cytotoxic T lymphocytes.

Definition of the T-lymphocyte responses to dengue viruses should aid in the development of safe and effective vaccines and help to explain the pathophysiology of dengue hemorrhagic fever and dengue...Full Text Available

1989-06-01

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Immunogenicity, efficacy, safety and effectiveness of pneumococcal conjugate vaccines (1998-2006)

The identification of the protein targets for dengue virus-specific T lymphocytes may be useful for planning the development of subunit vaccines against dengue. We studied the recognition by murine...Full Text Available

1993-02-01

19

British Library Electronic Table of Contents (United Kingdom)

In this paper we present an overview of the literature on efficacy and safety trials of the various pneumococcal conjugate vaccines on the market (PCV7) and in development (PCV9, PCV11 and allegedly PCV10 and PCV13), as well as of observations from post-licensure studies. Seven- (PCV7) and nine-valent PCV (PCV9) are reported to be sufficiently immunogenic after administration of a 3+1 schedule in infants in various RCTs. PncOMPC (PCV7 with a protein of N. meningitidis as a carrier) is less immunogenic, though this may have no repercussions for the protective efficacy against clinical disease. PCV7 is 82-97% efficacious against vaccine serotype (VT) IPD, 90% efficacious against (clinically diagnosed) pneumococcal pneumonia, and, like the 11-valent PCV, 57% efficacious against VT acute otiti...

2007-01-01

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An oral nervous necrosis virus vaccine using Vibrio anguillarum as an expression host provides early protection

British Library Electronic Table of Contents (United Kingdom)

Oral vaccination is the most desirable immunization method by which to prevent fish disease occurring at the early larval stage. We developed an Escherichia coli-based oral nervous necrosis virus (NNV) subunit vaccine and demonstrated its effectiveness in orange spotted grouper (Epinephelus coioides) fry. However, the incubation period was determined to be over 2weeks. To enhance the efficacy and shorten the incubation period, a safe and digestible biological adjuvant should be found. Vibrio anguillarum, a common marine bacterium with immune-stimulatory capability was selected as an expression host. An expression vector containing its heat shock protein 60 gene (groE) as an inducible promoter was constructed to express recombinant NNV coat protein as an antigen. The recombinant V. anguilla...

2011-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

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Design and Analysis of Vaccine Studies Questions of Analysis, Geometry & Algorithmics

Immunogenicity, efficacy, safety and effectiveness of pneumococcal conjugate vaccines (1998-2006).

Design and Analysis of Vaccine Studies

2010-01-01

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Vaccination against hepatitis A virus in French hemophilic children.

In this paper we present an overview of the literature on efficacy and safety trials of the various pneumococcal conjugate vaccines on the market (PCV7) and in development (PCV9, PCV11 and allegedly PCV10 and PCV13), as well as of observations from post-licensure studies. Seven- (PCV7) and nine-valent PCV (PCV9) are reported to be sufficiently immunogenic after administration of a 3+1 schedule in infants in various RCTs. PncOMPC (PCV7 with a protein of N. meningitidis as a carrier) is less immunogenic, though this may have no repercussions for the protective efficacy against clinical disease. PCV7 is 82-97% efficacious against vaccine serotype (VT) IPD, 90% efficacious against (clinically diagnosed) pneumococcal pneumonia, and, like the 11-valent PCV, 57% efficacious against VT acute otitis media. Naturally, it would be of paramount public health interest if the same levels of efficacy and effectiveness could be achieved ...

2006-12-04

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Influenza

Medline Plus

... a flu shot There is a new nasal spray version of the vaccine, and it contains weakened ... the LAIV (Live Attenuated Influenza Vaccine). The nasal-spray flu vaccine contains three different live but weakened ...

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CDC - Seasonal Influenza (Flu) - Q & A: 2007-08 Influenza (Flu...

PMID:7483502

1995-01-01

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CDC - Seasonal Influenza (Flu) - Q & A: 2006-07 Influenza (Flu...

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

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CDC - Seasonal Influenza (Flu) - Q & A about the 2010-2011 Flu...

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

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Response to measles-mumps-rubella vaccine in children on dialysis.

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

28

Construction and evaluation of a double mutant of Shigella flexneri as a candidate for oral vaccination against shigellosis.

Ten children receiving maintenance dialysis were immunized with the standard dose of measles-mumps-rubella vaccine between 15 and 33 months of age. Immune responses to vaccination were determined using commercially available enzyme-linked immunosorbent assays for measles, mumps, and rubella viruses. Eight children responded to measles vaccine, 5 to mumps vaccine, 8 to rubella vaccine, and only 3 children to all three vaccines, compared with a seroconversion rate of over 90% to all three vaccines in healthy children (P less than 0.0001). We contend that the relatively poor immunocompetence of our dialysis patients explains their less than optimal vaccine response and suggest that children vaccinated while undergoing dialysis be tested to confirm serological evidence of immunity. PMID:1571219

1992-03-01

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Review on the immunology of European sea bass Dicentrarchus labrax

Based on studies on the genetic and molecular basis of Shigella flexneri invasive properties, we have constructed and evaluated a double mutant of S. flexneri serotype 5 for utilization as a live attenuated oral vaccine against shigellosis. The first mutation, icsA, blocks intracellular spread of bacteria as well as cell-to-cell infection. It affects the capacity of the invasive pathogen to form large abscesses in epithelia. The second mutation, iuc, eliminates production of the siderophore aerobactin thus impairing growth of the bacterium within tissues. This double mutant, SC5700 appeared safe when administered intragastrically to macaque monkeys as three doses (5 x 10(10) c.f.u. each) at weekly intervals. Protection against a challenge by the wild type isolate (M90T) was observed 4 weeks after the last vaccine inoculation. Duration of carriage was considerably reduced as compared to the control group in which all animals had ...

1989-10-01

30

British Library Electronic Table of Contents (United Kingdom)

European sea bass (Dicentrarchus labrax L.) is a marine species of great economic importance, particularly in Mediterranean aquaculture. However, numerous pathogenic viruses, bacteria, fungi and parasites affect the species, causing various infectious diseases and thereby leading to the most heavy losses in aquaculture production of sea bass. In this respect, knowledge on molecular and genetic mechanisms of resistance to pathogens and specific features of immune response against various infectious agents should greatly benefit the development of effective vaccines and proper vaccination strategies in marker-assisted selection of fish resistant to a range of infections. To date, genetic knowledge on sea bass immune regulatory genes responsible for resistance to pathogens is relatively poor ...

2007-01-01

31

Intravaginal immunization using the recombinant HIV-1 clade-C trimeric envelope glycoprotein CN54gp140 formulated within lyophilized solid dosage forms

British Library Electronic Table of Contents (United Kingdom)

Vaccine-mediated prevention of primary HIV-1 infection at the heterosexual mucosal portal of entry may be facilitated by highly optimised formulations or drug delivery devices for intravaginal (i.vag) immunization. Previously we described hydroxyethylcellulose (HEC)-based rheologically structured gel vehicles (RSVs) for vaginal immunization of an HIV-1 vaccine candidate, a soluble recombinant trimeric HIV-1 clade-C envelope glycoprotein designated CN54gp140. Here we investigated the efficacy of lyophilized solid dosage formulations (LSDFs) for prolonging antigen stability and as i.vag delivery modalities. LSDFs were designed and developed that upon i.vag administration they would reconstitute with the imbibing of vaginal fluid to mucoadhesive, site-retentive semi-solids. Mice were immunize...

2011-01-01

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Murine antibody response to oral infection with live aroA recombinant Salmonella dublin vaccine strains expressing filamentous hemagglutinin antigen from Bordetella pertussis.

Population-based prevention of influenza in Dutch general practice.

Two plasmids which express either nearly intact or truncated filamentous hemagglutinin (FHA) from Bordetella pertussis and which are marked with a tetracycline resistance (Tcr) gene were transformed into Salmonella dublin SL1438, an aroA deletion mutant intended for use as an attenuated oral vaccine against salmonellosis. These S. dublin recombinants, when fed to mice, induced serum immunoglobulin, immunoglobulin M (IgM), and sometimes IgA antibody responses to FHA and S. dublin. In addition, IgA antibodies against FHA were found in gut wash fluids. S. dublin carrying pDB2300, a multicopy plasmid encoding truncated FHA protein, induced a better antibody response than did S. dublin carrying pDB2000, a low-copy-number plasmid encoding full-sized FHA. Administration of tetracycline to mice enhanced the stability of recombinant plasmids, and tetracycline-treated mice developed higher anti-FHA titers. Although neither strain examined is suitable for ...

1990-08-01

33

Novel Approach for Differential Diagnosis of HIV Infections in the Face of Vaccine-Generated Antibodies

BACKGROUND: Although the effectiveness of influenza vaccination in high-risk groups has been proven, vaccine coverage continues to be less than 50% in The Netherlands. To improve vaccination rates,...Full Text Available

1997-06-01

34

Contrasting Population Structures of the Genes Encoding Ten Leading Vaccine-Candidate Antigens of the Human Malaria Parasite, Plasmodium falciparum

SummaryBecause increasing numbers of HIV vaccine candidates are being tested globally, it is essential to differentiate vaccine-from virus-induced antibodies. Most of the currently...Full Text Available

2006-11-01

35

A semi-qualitative study of attitudes to vaccinating adolescents against human papillomavirus without parental consent

The extensive diversity of Plasmodium falciparum antigens is a major obstacle to a broadly effective malaria vaccine but population genetics has rarely been used to guide vaccine design....Full Text Available

36

Biotechnology developments in the livestock sector in developing countries.

BackgroundThe first vaccine to prevent human papillomavirus (HPV) and cervical cancer has been licensed, and in future, vaccination may be routinely offered to 10–14 year...Full Text Available

37

Novel Techniques and Their Wide Applications to Health Foods, Medical and Agricultural Biotechnology in Relation to Policy Making on Genetically Modified Crops and Foods

Global meat and milk consumption is exponentially increasing due to population growth, urbanization and changes in lifestyle in the developing world. This is an excellent opportunity for developing countries to improve the livestock sector by using technological advances. Biotechnology is one of the avenues for improved production in the "Livestock revolution". Biotechnology developments applied to livestock health, nutrition, breeding and reproduction are improving with a reasonable pace in developing countries. Simple bio-techniques such as artificial insemination have been well implemented in many parts of the developing world. However, advanced technologies including transgenic plant vaccines, marker assisted selection, solid state fermentation for the production of fibrolytic enzymes, transgenic fodders, embryo transfer and animal cloning are confined ...

2010-01-01

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Tat-Neutralizing Antibodies in Vaccinated Macaques

Selected applications of novel techniques in Agricultural Biotechnology, Health Food formulations and Medical Biotechnology are being reviewed with the aim of unraveling future developments and policy changes that are likely to open new markets for Biotechnology and prevent the shrinking or closing of existing ones. Amongst the selected novel techniques with applications in both Agricultural and Medical Biotechnology are: immobilized bacterial cells and enzymes, microencapsulation and liposome production, genetic manipulation of microorganisms, development of novel vaccines from plants, epigenomics of mammalian cells and organisms, and biocomputational tools for molecular modeling related to disease and Bioinformatics. Both fundamental and applied aspects of the emerging new techniques are being discussed in relation to their anticipated, marked impact on future markets and present policy changes that are needed for success ...

2004-01-01

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Safety and Immunogenicity of Novel Recombinant BCG and Modified Vaccinia Virus Ankara Vaccines in Neonate Rhesus Macaques ?

The human immunodeficiency virus Tat protein is essential for virus replication and is a candidate vaccine antigen. Macaques immunized with Tat or chemically modified Tat toxoid having the same clade...Full Text Available

2003-03-01

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Pathway to Licensure for Protective Antigen-based Anthrax Vaccines ...

Although major inroads into making antiretroviral therapy available in resource-poor countries have been made, there is an urgent need for an effective vaccine administered shortly after birth, which...Full Text Available

2010-08-01

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Mothers' concept of measles and attitudes towards the measles vaccine in Ile-Ife, Nigeria.

... Weiss, S., D. Kobiler, H. Levy, H. Marcus, A. Pass, N. Rothschild, and Z ... of Bacillus anthracis spores conferred by a protective antigen-based vaccine in rabbits ...

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Molecular characterization of a Chinese variant of the Flury-LEP strain

The attitude of Nigerian mothers, mainly Yoruba, towards measles vaccine and other aspects of prevention are influenced by different perceptions of the cause of measles. There is a significant correlation...Full Text Available

1982-09-01

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Indian vaccine innovation: the case of Shantha Biotechnics

The entire genome of rabies virus vaccine strain Flury-LEP-C, a Chinese variant of the rabies virus vaccine strain Flury-LEP, was sequenced. The overall length of the genome of Flury-LEP-C strain was...Full Text Available

44

Cryoglobinaemia in rabbits hyperimmunized with a polyvalent pneumococcal vaccine

BackgroundAlthough the World Health Organization had recommended that every child be vaccinated for Hepatitis B by the early 1980s, large multinational pharmaceutical companies held...Full Text Available

45

Correlates to Increased Lethality of Attenuated Venezuelan Encephalitis Virus Vaccine for Immunosuppressed Hamsters.

During the anamnestic response, the sera of four rabbits immunized with a polyvalent pneumococcal vaccine contained large amounts of cryoglobulins belonging to the G and M immunoglobulin classes. These...Full Text Available

1965-10-01

46

A viral vaccine encoding PSA induces antigen spreading to a common set of self proteins in prostate cancer patients

Splenectomy or pretreatment of adult hamsters with cyclophosphamide (Cytoxan) increased the lethality of the TC-83 vaccine strain of Venezuelan encephalitis virus (VEE), inoculated subcutaneously, from 12% for normal hamsters to 75 and 76% respectively. A...

1974-01-01

47

Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects

PurposeWe previously reported a randomized phase II clinical trial combining a poxvirus-based vaccine encoding PSA with radiotherapy in patients with localized prostate...Full Text Available

2010-08-01

48

Long-Term Specific Immune Responses Induced in Humans by a Human Immunodeficiency Virus Type 1 Lipopeptide Vaccine: Characterization of CD8⁺-T-Cell Epitopes Recognized

The effect of abatacept, a selective T-cell co-stimulation modulator, on vaccination has not been previously investigated. In this open-label, single-dose, randomized, parallel-group, controlled study,...Full Text Available

2007-01-01

49

Comparison of a multivalent viral vaccine program versus a univalent viral vaccine program on animal health, feedlot performance, and carcass characteristics of feedlot calves

We studied the effect of booster injections and the long-term immune response after injections of an anti-human immunodeficiency virus type 1 (HIV-1) lipopeptide vaccine. This vaccine was injected alone...Full Text Available

2003-10-01

50

Science and Technology Review July/August 2010

A field study was conducted under commercial feedlot conditions at 2 sites in western Canada to determine the relative effects of a univalent viral vaccine (MLV 1) program versus a multivalent viral...Full Text Available

2003-01-01

51

Methanogen community structure in the rumens of farmed sheep, cattle and red deer fed different diets

This issue has the following articles: (1) Deterrence with a Minimum Nuclear Stockpile - Commentary by Bruce T. Goodwin; (2) Enhancing Confidence in the Nation's Nuclear Stockpile - Livermore experts are participating in a national effort aimed at predicting how nuclear weapon materials and systems will likely change over time; (3) Narrowing Uncertainties - For climate modeling and many other fields, understanding uncertainty, or margin of error, is critical; (4) Insight into a Deadly Disease - Laboratory experiments reveal the pathogenesis of tularemia in host cells, bringing scientists closer to developing a vaccine for this debilitating disease. (5) Return to Rongelap - On the Rongelap Atoll, Livermore scientists are working to minimize radiological exposure for natives now living on or wishing to return to the islands.

2010-05-27

52

British Library Electronic Table of Contents (United Kingdom)

Abstract Development of inhibitors and vaccines that mitigate rumen-derived methane by targeting methanogens relies on knowledge of the methanogens present. We investigated the composition of archaeal communities in the rumens of farmed sheep (Ovis aries), cattle (Bos taurus) and red deer (Cervus elaphus) using denaturing gradient gel electrophoresis (DGGE) to generate fingerprints of archaeal 16S rRNA genes. The total archaeal communities were relatively constant across species and diets, and were less variable and less diverse than bacterial communities. There were diet- and ruminant-species-based differences in archaeal community structure, but the same dominant archaea were present in all rumens. These were members of three coherent clades: species related to Methanobrevibacter ruminan...

2011-01-01

53

Chloroquine for influenza prevention: a randomised, double-blind, placebo controlled trial

British Library Electronic Table of Contents (United Kingdom)

Background: Chloroquine has in-vitro activity against influenza and could be an ideal candidate for worldwide prevention of influenza in the period between onset of a pandemic with a virulent influenza strain and the development and widespread dissemination of an effective vaccine. We aimed to assess the efficacy of such an intervention. Methods: In this randomised, double-blind, placebo-controlled trial done at a single centre in Singapore, we randomly assigned (1:1) healthy adults to receive chloroquine phosphate (500 mg/day for 1 week, then once a week to complete 12 weeks) or matching placebo by use of a computer-generated randomisation list. Participants filled an online symptom diary every week, supplemented by daily diaries and self-administered nasal swabs when unwell. Haemagglutin...

2011-01-01

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The immunological era in melanoma treatment: new challenges for heat shock protein-based vaccine in the advanced disease

British Library Electronic Table of Contents (United Kingdom)

Introduction: Tumor-derived heat shock protein (HSP)-peptide complexes (HSPPCs) induced immunity against malignancies in preclinical trials, working across tumor types and bypassing the need to identify single immunogenic peptides. These results paved the way for the use of human gp96 obtained from autologous tumor samples as an anti-cancer vaccine. Areas covered: Autologous tumor-derived HSP gp96 peptide complex (HSPPC-96) vaccine is emerging as a tumor- and patient-specific cancer vaccine, with confirmed activity in several malignancies. It has been tested in Phase III clinical trials in advanced melanoma and kidney cancer with evidence for efficacy in patients with earlier stage disease. HSPPC-96-based vaccine demonstrated an excellent safety profile, thus emerging as a novel therapeuti...

2011-01-01

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The Case for Reactive Mass Oral Cholera Vaccinations

IntroductionThe outbreak of cholera in Zimbabwe intensified interest in the control and prevention of cholera. While there is agreement that safe water, sanitation, and personal...Full Text Available

56

Reversing B cell aging

Reporting Problems to FDA

Age-related alterations in the cellular composition of the B lineage are a major cause of the poor antibody response to vaccination and to infectious agents among the elderly population. The mechanisms...Full Text Available

57

Medline Plus

Enter Search terms A-Z Index Home Food Drugs Medical Devices Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Radiation-Emitting Products Tobacco ...

58

Health Information for Travelers to South Africa - Travelers...

Health Information for Travelers to Somalia - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) South Africa Regions Vaccinations News & Announcements Travel...

2011-08-28

59

Health Information for Travelers to Saudi Arabia - Travelers...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Somalia Regions Vaccinations News & Announcements Travel...

2011-08-28

60

Health Information for Travelers to Rwanda - Travelers' Health...

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2011-08-28

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Health Information for Travelers to Mozambique - Travelers' Health...

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Health Information for Travelers to Malawi - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Mozambique Regions Vaccinations News & Announcements Travel...

2011-08-28

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Health Information for Travelers to Kenya - Travelers' Health...

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2011-08-28

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Health Information for Travelers to Iran - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Kenya Regions Vaccinations News & Announcements Travel Notices...

2011-08-28

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Health Information for Travelers to Gabon - Travelers' Health...

please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Iran Regions Vaccinations News & Announcements Travel Notices Diseases Yellow Book Contents...

2011-09-04

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Health Information for Travelers to Ethiopia - Travelers' Health...

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Health Information for Travelers to Eritrea - Travelers' Health...

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2011-08-28

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Health Information for Travelers to Equatorial Guinea - Travelers...

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Health Information for Travelers to Djibouti - Travelers' Health...

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Health Information for Travelers to Democratic Republic of the...

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Health Information for Travelers to Antarctica - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Democratic Republic of the Congo Regions Vaccinations News &...

2011-08-28

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more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Antarctica Regions Vaccinations News & Announcements Travel...

2011-08-28

73

Diphtheria in Europe.

Controlling Endemic Cholera with Oral Vaccines

A letter of inquiry was sent to 21 countries in Europe to ascertain their experience of diphtheria during the last 20 years. An analysis of the 15 replies showed that all relied on childhood vaccination...Full Text Available

1984-12-01

74

Bioterrorism and Biocrimes: The Illicit Use of Biological Agents ...

BackgroundAlthough advances in rehydration therapy have made cholera a treatable disease with low case-fatality in settings with appropriate medical care, cholera continues...Full Text Available

2007-11-01

75

A multifactorial strategy of pain management is associated with less pain in scheduled vaccination of children. A study realized by family practitioners in 239 children aged 4-12 years old

... view on the utility of such attacks, see JH Rothschild, Tomorrow's Weapons ... Aum Shinrikyo may have had a stolen vaccine anthrax strain incapable ...

2001-02-01

76

British Library Electronic Table of Contents (United Kingdom)

Background and aims. The multiplicity of vaccine injections during childhood leads to iterative painful and stressful experiences which may lead in turn to anticipated pain and then possibly to a true needle phobia. We aimed at evaluating a multifactorial strategy of pain management combining pharmacological and non-pharmacological approaches during vaccination, as compared to usual care, in 4- to 12-year-old children. Methods. In all, 239 children were enroled by 25 family practitioners in an open-label study. After a pseudo-randomization, usual pain management (n = 132) was compared to a multifactorial strategy (n = 107) associating preliminary application of an anesthesic patch, preferential use of specified vaccines, child education by the parents and the doctor, parental accompaniment...

2008-01-01

77

A Novel Multi-Antigen Virally Vectored Vaccine against Mycobacterium avium Subspecies paratuberculosis

Investigation of xenotropic murine leukemia virus-related virus (XMRV) in human and other cell lines.

BackgroundMycobacterium avium subspecies paratuberculosis causes systemic infection and chronic intestinal inflammation in many species including...Full Text Available

78

Concise review: expanding roles for hematopoietic cellular therapy and the blood transfusion services.

Xenotropic murine leukemia virus-related virus (XMRV) was discovered in human prostate tumors and later in some chronic fatigue syndrome (CFS) patients. However, subsequent studies have identified various sources of potential contamination with XMRV and other murine leukemia virus (MLV)-related sequences in test samples. Biological and nucleotide sequence analysis indicates that XMRV is distinct from known xenotropic MLVs and has a broad host range and cell tropism including human cells. Therefore, it is prudent to minimize the risk of human exposure to infection by evaluating XMRV contamination in cell lines handled in laboratory research and particularly those used in the manufacture of biological products. Nested DNA PCR assays were optimized for investigating XMRV gag and env sequences in various cell lines, which included MRC-5, Vero, HEK-293, MDCK, HeLa, and A549, that may be used in the development of some vaccines and other cell lines ...

2011-10-11

79

Preliminary Assessment of the Safety and Immunogenicity of a New CTX?-Negative, Hemagglutinin/Protease-Defective El Tor Strain as a Cholera Vaccine Candidate

Hematopoietic stem cells (HSCs) have remained at the forefront of stem cell research for the past 50 years, since the therapeutic potential of bone marrow transplantation was realized. Uniquely, among stem and progenitor cells, research progress has been made in parallel between the laboratory benchtop and hospital bedside during this period. Integral to this work has been the role of the transfusion medicine services in the collection, storage, and processing of HSCs. The next decade promises to bring further developments: with new fields of cellular therapies, stem cell vaccination, and stem cell drug testing opening up. This article summarizes exciting areas of research concerning the behavior and potential clinical applications of HSCs. For the purposes of clarity, we describe in turn the trafficking and transfer of HSCs; ex vivo expansion of HSC units from different sources; and finally, applications of specifically selected subsets of ...

2011-09-01

80

Potent immune responses and in vitro pro-inflammatory cytokine suppression by a novel adenovirus vaccine vector based on rare human serotype 28

Vibrio cholerae 638 (El Tor, Ogawa), a new CTXΦ-negative hemagglutinin/protease-defective strain that is a cholera vaccine candidate, was examined for safety and immunogenicity...Full Text Available

1999-02-01

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81

Molecular Characterization of a Haemaphysalis longicornis Tick Salivary Gland-Associated 29-Kilodalton Protein and Its Effect as a Vaccine against Tick Infestation in Rabbits

Adenovirus vaccine vectors derived from rare human serotypes have been shown to be less potent than serotype 5 (Ad5) at inducing immune responses to encoded antigens. To identify highly immunogenic...Full Text Available

2010-08-09

82

Efficacy of a heat inactivated hepatitis B vaccine in male homosexuals: outcome of a placebo controlled double blind trial.

The use of tick vaccines in mammalian hosts has been shown to be the most promising alternative tick control method to current use of acaricides, which suffers from a number of limitations. However,...Full Text Available

1999-04-01

83

Effects of 2 commercially-available 9-way killed vaccines on milk production and rectal temperature in Holstein-Friesian dairy cows.

The efficacy of a heat inactivated hepatitis B virus vaccine, containing 3 micrograms hepatitis B surface antigen (HBsAg), was studied in a high risk group of 800 susceptible homosexual men by a randomised...Full Text Available

1983-04-23

84

A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins

Veterinarians and farmers employing multivalent killed vaccines in lactating dairy cows have reported transient losses in milk production. Few studies have quantified this loss. In this report, effects...Full Text Available

2001-10-01

85

A Randomized Trial Assessing the Safety and Immunogenicity of AS01 and AS02 Adjuvanted RTS,S Malaria Vaccine Candidates in Children in Gabon

The Yellow Fever Vaccine 17D (YFV17D) has been used as a vector for the Lassa virus glycoprotein precursor (LASV-GPC) resulting in construction of YFV17D/LASV-GPC recombinant virus. The virus...Full Text Available

2006-02-20

86

Serological testing-An alternative to boosters?

BackgroundThe malaria vaccine candidate antigen RTS,S includes parts of the pre-erythrocytic stage circumsporozoite protein fused to the Hepatitis B surface antigen. Two Adjuvant...Full Text Available

87

British Library Electronic Table of Contents (United Kingdom)

The issue of the duration of immunity, particularly for the modified live viral components of veterinary vaccines, has been a significant part of the recent vaccination debate. One manufacturer has increased the recommended booster interval for these components to 3 years give name and another now states `up to 4 years' immunity.There remain many unanswered questions regarding this duration of immunity (DOI). Studies suitable for data sheet claims are time consuming and costly and can only be performed in laboratory dogs under tightly controlled conditions. Evidence from rabies serology testing in the UK shows that the response of individual animals to routine vaccination is highly variable. Much of the published field evidence on the persistence of antibody titres originates from North Am...

2006-01-01

88

Therapeutic Vaccination in Chronic Hepatitis B: Preclinical Studies in the Woodchuck

The hemoglobins of the trematodes Fasciola hepatica and Paramphistomum epiclitum: A molecular biological, physico-chemical, kinetic, and vaccination study

Recommended treatment of chronic hepatitis B with interferon-α and/or nucleos(t)ide analogues does not lead to a satisfactory result. Induction of HBV-specific T cells by therapeutic...Full Text Available

2010-01-01

89

Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs

The trematode Fasciola hepatica (Fa.he.) is a common parasite of human and livestock. The hemoglobin (Hb) of Fa.he., a potential immunogen, was chosen for characterization...Full Text Available

2008-10-01

90

Taking social relationships seriously: Lessons learned from the informed consent practices of a vaccine trial on the Kenyan Coast

BackgroundTrypanosoma cruzi, the etiologic agent of Chagas Disease, is a major vector borne health problem in Latin America and an emerging...Full Text Available

91

Strategies for the production of genetically identical monkeys by embryo splitting

AbstractIndividual informed consent is a key ethical obligation for clinical studies, but empirical studies show that key requirements are often not met. Common recommendations to strengthen...Full Text Available

2008-09-01

92

Serum Concentrations of Antibodies Against Vaccine Toxoids in Children Exposed Perinatally to Immunotoxicants

Genetically identical rhesus monkeys would have tremendous utility as models for the study of human disease and would be particularly valuable for vaccine trials and tissue transplantation studies where...Full Text Available

93

Rubella screening and vaccination program for US Air Force trainees: an analysis of findings.

BackgroundPolychlorinated biphenyls (PCBs) may cause immunotoxic effects, but the detailed dose–response relationship and possible vulnerable time windows of exposure are...Full Text Available

2010-10-01

94

Prevention of clinical coliform mastitis in dairy cows by a mutant Escherichia coli vaccine.

A preventive medicine program of rubella control for trainees at the Air Force Military Training Center, Lackland AFB, Texas, was begun in October 1977. Incoming trainees were screened for rubella susceptibility,...Full Text Available

1982-03-01

95

Polyantigenic Interferon-? Responses Are Associated with Protection from TB among HIV-Infected Adults with Childhood BCG Immunization

A prospective cohort study was undertaken in two commercial California dairies. The treatment group, 246 cows, received three doses of a whole cell bacterin of J5 Escherichia coli (mutant of E. coli...Full Text Available

1989-07-01

96

Poliomyelitis control in Israel, the West Bank and Gaza Strip: changing strategies with the goal of eradication in an endemic area.

BackgroundSurrogate immunologic markers for natural and vaccine-mediated protection against tuberculosis (TB) have not been identified.MethodsHIV-infected...Full Text Available

97

Plasminogen-¹²⁵I responses in dogs to a single injection of urokinase and typhoid vaccine and to vascular injury

Israel has faced the challenge presented by epidemic poliomyelitis by using different immunization strategies. In the 1950s, inactivated poliovirus vaccine (IPV) helped to reduce the total burden of...Full Text Available

1994-01-01

98

Peptide Nanoparticles as Novel Immunogens: Design and Analysis of a Prototypic Severe Acute Respiratory Syndrome Vaccine

In vivo plasminogen responses to various stimuli were studied. Plasminogen-¹²⁵I was prepared and used first for metabolic studies of plasminogen in control dogs. The average results were:...Full Text Available

1972-06-01

99

Passive immunity to feline leukemia: evaluation of immunity from dams naturally infected and experimentally vaccinated.

Severe acute respiratory syndrome (SARS) is an infectious disease caused by a novel coronavirus that cost nearly 800 lives. While there have been no recent outbreaks of the disease, the threat...Full Text Available

2009-01-01

100

LOUSE-BORNE BACTERIAL PATHOGENS IN LICE (PHTHIRAPTERA) OF RODENTS AND CATTLE FROM EGYPT

Antibodies against feline leukemia virus (FeLV) and the feline oncornavirus-associated cell membrane antigen (FOCMA) were transferred from pregnant cats to their suckling kittens. All of these kittens...Full Text Available

1977-04-01

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101

In vitro antigen-induced antibody responses to hepatitis B surface antigen in man. Kinetic and cellular requirements.

... were erroneous. The oriental rat flea, Xenopsylla cheopis Rothschild, is considered to be the primary vector of ... laboratory and production of Weigl's exanthematous typhus vaccine. In Maintenance of hum...

102

Improvement of a Dendritic Cell-Based Therapeutic Cancer Vaccine with Components of Toxoplasma gondii?

In this report we define the parameters of the human immune response after immunization with hepatitis B vaccine. 2 wk after booster immunization, there is significant spontaneous secretion of antibody...Full Text Available

1984-10-01

103

Genomic Expression Libraries for the Identification of Cross-Reactive Orthopoxvirus Antigens

The use of dendritic cells (DCs) as a cellular adjuvant is a promising approach to the immunotherapy of cancer. It has previously been demonstrated that DCs pulsed ex vivo with Toxoplasma gondii...Full Text Available

2009-10-01

104

Genomic Content of Bordetella pertussis Clinical Isolates Circulating in Areas of Intensive Children Vaccination

Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young non-vaccinated persons have renewed interest in this zoonotic disease. Usually causing...Full Text Available

105

Evaluation of Two Homologous Proline-Rich Proteins of Coccidioides posadasii as Candidate Vaccines against Coccidioidomycosis?

BackgroundThe objective of the study was to analyse the evolution of Bordetella pertussis population and the influence of herd immunity in different areas of the...Full Text Available

106

CDC - Seasonal Influenza (Flu) - Questions and Answers - Guillain...

Evaluation of the protective efficacy of recombinant T-cell-reactive proteins of Coccidioides posadasii in a murine model of coccidioidomycosis has led to the discovery of potential...Full Text Available

2007-12-01

107

CDC - Malaria - Malaria Worldwide - How Can Malaria Cases and...

Effectiveness Flu Shot Nasal Spray Vaccine (LAIV) Thimerosal Guillain-Barré Syndrome (GBS) Antiviral Drugs: Key Facts Antiviral Drugs: Q&A Antiviral Drug Resistance Links,...

2011-09-24

108

Auditing the Management of Vaccine-Preventable Disease Outbreaks: The Need for a Tool

vaccination card during trial enrollment at the KEMRI/CDC site in Kenya. (Alan Rubin, KEMRI) KEMRI Clinical Officer Paul Ogai reviews a prospective participant's...

2011-09-24

109

Immunological correlates for protection against intranasal challenge of Bacillus anthracis spores conferred by a protective antigen-based vaccine in rabbits.

Public health activities, especially infectious disease control, depend on effective teamwork. We present the results of a pilot audit questionnaire aimed at assessing the quality of public health services...Full Text Available

110

Genetic control of immune response to pseudorabies and atrophic rhinitis vaccines: II. Comparison of additive direct and maternal genetic effects.

Correlates between immunological parameters and protection against Bacillus anthracis infection in animals vaccinated with protective antigen (PA)-based vaccines could provide surrogate markers to evaluate the putative protective efficiency of immunization in humans. In previous studies we demonstrated that neutralizing antibody levels serve as correlates for protection in guinea pigs (S. Reuveny et al., Infect. Immun. 69:2888-2893, 2001; H. Marcus et al., Infect. Immun. 72:3471-3477, 2004). In this study we evaluated similar correlates for protection by active and passive immunization of New Zealand White rabbits. Full immunization and partial immunization were achieved by single and multiple injections of standard and diluted doses of a PA-based vaccine. Passive immunization was carried out by injection of immune sera from rabbits vaccinated with PA-based vaccine prior to ...

2006-01-01

111

Serotypes and susceptibilities of paediatric clinical isolates of Streptococcus pneumoniae in Crete, Greece, before and after the heptavalent pneumococcal conjugate vaccine.

Data from 52 litters farrowed in two seasons of a cross-fostering experiment were analyzed to estimate variances and covariances for additive direct and maternal genetic effects on immune response to pseudorabies virus and B. bronchiseptica vaccine. Twenty purebred boars and 44 sows of the Duroc, Landrace and Yorkshire breeds were used. Immune response was measured after vaccine challenge. A modified-live pseudorabies (PR) vaccine was administered to piglets at 28 d of age; response was measured by log2 serum neutralization titers at 56 d. An inactivated B. bronchiseptica bacterin was administered at 28, 42 and 112 d. Antibody levels were measured relative to positive and negative controls at 28, 56 and 119 d by using an enzyme-linked immunosorbent assay (ELISA). Results from this study for heritability were .18 +/- .09 for PR titer and .15 +/- .07 and .52 +/- .15 for 56- and 119-d ELISA values, respectively. The ...

1987-02-01

112

Cochrane Review: Polysaccharide vaccines for preventing serogroup A meningococcal meningitis

All Streptococcus pneumoniae strains isolated from paediatric clinical samples at Heraklion University General Hospital in the 10-year period 2000-2009 were tested for serotype and susceptibility to antimicrobials. Among a total of 258 strains, 159 were isolated in the 5-year period 2000-2004, before the introduction of the heptavalent pneumococcal conjugate vaccine (PCV7), and 99 in the post-PCV7 5-year period 2005-2009. The prevalence of PCV7-included serotypes decreased in the post-PCV7 period (p?=?0.0002), but an increase was observed for serotypes 7F (p?=?0.002) and 19A (p?=?0.004). Pan-susceptibility rates and susceptibility to cotrimoxazole increased in the post-PCV7 period (p?=?0.01 and p?=?0.008, respectively), but serotype 19A emerged as a contributor to multi-resistance (p?=?0.007). PCV7 was followed by decreased S. pneumoniae resistance and prevalence of vaccine-related serotypes but increased prevalence of serotypes 7F and 19A. ...

2010-07-10

113

British Library Electronic Table of Contents (United Kingdom)

AbstractBackground Randomised controlled trials (RCTs) in the 1970s and early 1980s showed the polysaccharide serogroup A vaccine (SgAV) prevented serogroup A meningococcal meningitis (SGAMM). Subsequent non-RCTs suggested significant variations in the age-specific duration of protection among children. Objectives To determine the protective effect, duration of protection, age-specific effects and the effect of booster doses in children of the SgAV against SGAMM. Search strategy We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2010, issue 2) which contains the Acute Respiratory Infections Group's Specialised Register, MEDLINE (January 1950 to May Week 3, 2010) and EMBASE (January 1974 to May 2010). Selection criteria We included RCTs. Non-RCTs ...

2011-01-01

114

Translation products of pre-S(1), pre-S(2) regions and the S gene of hepatitis B virus: susceptibility of their antigenic activities to treatment with heat, urea formalin or pepsin

Serum and salivary responses to oral tetravalent reassortant rotavirus vaccine in newborns.

Hepatitis B subviral particles, purified from plasma of asymptomatic carriers seropositive for hepatitis B e antigen, were treated with various conditions reported for the processing of vaccines. Thereafter,...Full Text Available

1986-12-01

115

Safety and immunogenicity of ERA strain of rabies virus propagated in a BHK-21 cell line.

Serum and salivary responses of 95 infants to either a standard (4 x 10(4) plaque-forming units (PFU), 47 neonates) or a high dose (4 x 10(5) PFU, 48 neonates) of tetravalent reassortant rhesus rotavirus...Full Text Available

1993-05-01

116

Recruitment of intestinal CD45RA+ and CD45RC+ cells induced by a candidate oral vaccine against porcine post-weaning colibacillosis.

The ERA strain of rabies virus was propagated in a baby hamster kidney cell line (BHK-21/C13). The viral titer was 10(1.8) tissue culture infective doses (TCID) higher than that of commercial ERA vaccine....Full Text Available

1989-10-01

117

Invasiveness and persistence of Salmonella enteritidis, Salmonella typhimurium, and a genetically defined S. enteritidis aroA strain in young chickens.

To assess the influence of a live attenuated oral vaccine against porcine post-weaning colibacillosis (PWC) induced by enterotoxigenic Escherichia coli (ETEC) on mucosal lymphoid cell CD45 isoforms expression, experimental group of weaned pigs (n=6) was immunized orally with F4ac+ non-ETEC strain (day 0) and challenged with F4ac+ ETEC strain 7 days latter. Non-immunized ETEC-infected pigs (n=6) served as control. All pigs were killed on post-challenge day 7. The small intestine was excised for isolation of jejunal lamina propria (JLP) and ileal Peyer's patch (IPP) lymphocytes and immunohistochemical studies. The results obtained by immunophenotyping of isolated cells show that the proportion of CD45RA+ and CD45RC+ JLP, but not IPP, cells were higher in the non-ETEC-immunized ETEC-infected pigs versus non-immunized infected. Additionally, while CD45RA+ JLP cells increased only slightly, the expression of CD45RC isoform on the JLP cells was significantly higher ...

2002-07-01

118

Interferon-? expressed by a rabies virus-based HIV-1 vaccine vector serves as a molecular adjuvant and decreases pathogenicity

Newly hatched chicks were dosed orally with a Salmonella typhimurium wild-type strain, an S. enteritidis wild-type strain, and a genetically defined S. enteritidis aroA vaccine candidate, strain CVL30....Full Text Available

1994-11-01

119

Induction of Antibody Responses to African Horse Sickness Virus (AHSV) in Ponies after Vaccination with Recombinant Modified Vaccinia Ankara (MVA)

Type I interferon is important in anti-viral responses and in coordinating the innate immune response. Here we explore the use of interferon-β to adjuvant the response to a rabies virus...Full Text Available

2008-12-20

120

Helper T-Cell Epitopes Encoded by the Babesia bigemina rap-1 Gene Family in the Constant and Variant Domains Are Conserved among Parasite Strains

BackgroundAfrican horse sickness virus (AHSV) causes a non-contagious, infectious disease in equids, with mortality rates that can exceed 90% in susceptible horse populations....Full Text Available

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121

Differential Specificity and Immunogenicity of Adenovirus Type 5 Neutralizing Antibodies Elicited by Natural Infection or Immunization?

Among important candidates for babesial vaccines are apical complex proteins, including rhoptry-associated protein 1 (RAP-1) from Babesia bovis and B. bigemina, which...Full Text Available

1998-04-01

122

A progress for the health of south countries. The solar refrigerator; Un progres pour la sante dans les pays du Sud. Le refrigerateur solaire

A recent clinical trial of a T-cell-based AIDS vaccine delivered with recombinant adenovirus type 5 (rAd5) vectors showed no efficacy in lowering viral load and was associated with increased risk of...Full Text Available

2010-01-01

123

Efficient mitigation strategies for epidemics in rural regions

In order to conserve vaccines in hot countries a solar refrigerator has been made by a French university. It is a photothermal refrigerator without batteries. It uses two gases: ammonia and calcium chloride. The refrigerator is autonomous and can work eleven days without sun. (N.C.)

1998-05-01

124

Clinical aspects of Marburg hemorrhagic fever

Containing an epidemic at its origin is the most desirable mitigation. Epidemics have often originated in rural areas, with rural communities among the first affected. Disease dynamics in rural regions have received limited attention, and results of general studies cannot be directly applied since population densities and human mobility factors are very different in rural regions from those in cities. We create a network model of a rural community in Kansas, USA, by collecting data on the contact patterns and computing rates of contact among a sampled population. We model the impact of different mitigation strategies detecting closely connected groups of people and frequently visited locations. Within those groups and locations, we compare the effectiveness of random and targeted vaccinations using a Susceptible-Exposed-Infected-Recovered compartmental model on the contact network. Our simulations show that the targeted vaccinations of only 10% ...

2010-01-01

125

British Library Electronic Table of Contents (United Kingdom)

Marburg virus belongs to the genus Marburgvirus in the family Filoviridae and causes a severe hemorrhagic fever, known as Marburg hemorrhagic fever (MHF), in both humans and nonhuman primates. Similar to the more widely known Ebola hemorrhagic fever, MHF is characterized by systemic viral replication, immunosuppression and abnormal inflammatory responses. These pathological features of the disease contribute to a number of systemic dysfunctions including hemorrhages, edema, coagulation abnormalities and, ultimately, multiorgan failure and shock, often resulting in death. A detailed understanding of the pathological processes that lead to this devastating disease remains elusive, a fact that contributes to the lack of licensed vaccines or effective therapeutics. This article will review the...

2011-01-01

126

Low cytotoxicity effect of dendrosome as an efficient carrier for rotavirus VP2 gene transferring into a human lung cell line

British Library Electronic Table of Contents (United Kingdom)

The efficiency of dendrosome (a gene porter) was assessed in transferring recombinant human rotavirus VP2 cDNA into A549, a human lung cell line. After gene transferring, transmission electron microscopy showed core-like particles (CLPs) formation in the transfected cells both with dendrosome and lipofectamine porters. In addition, western blotting analysis showed that the expression of VP2 gene was almost equal in the dendrosome and lipofectamine-transfected cells. Also, the cytotoxicity studies revealed that dendrosome had a lower cytotoxicity than lipofectamine. Therefore, our study may introduce dendrosome as a possible carrier for gene transferring into the human lung cell line, especially, for intranasally administration of DNA vaccines.

2009-01-01

127

Global suppression of mitogen-activated ovine peripheral blood mononuclear cells by surface protein activity from Mycoplasma ovipneumoniae

British Library Electronic Table of Contents (United Kingdom)

Mycoplasma ovipneumoniae is associated with chronic non-progressive pneumonia of sheep and goats. As with many other mycoplasmas involved in animal diseases, protective immune responses have not been achieved with vaccines, even though antibody responses can be obtained. This study focuses on characterizing the interaction of M. ovipneumoniae with ovine PBMC using carboxy-fluorescein-succinimidyl-ester (CFSE) loading and flow cytometry to measure lymphoid cell division. M. ovipneumoniae induced a strong in vitro polyclonal suppression of CD4^+, CD8^+, and B blood lymphocyte subsets. The suppressive activity could be destroyed by heating to 60^oC, and partially impaired by formalin and binary ethyleneimine treatment that abolished its viability. The activity resided on the surface-exposed m...

2010-01-01

128

Estimates of quantitative genetic parameters of immunological traits in the chicken.

Diphtheria toxoid conformation in the context of its nanoencapsulation within liposomal particles sandwiched by chitosan

Three in vivo assays were used to measure the immunocompetence of chickens in two generations of a selection experiment. The obtained data were used to estimate the variance components for sire and dam for antibody production to Pasteurella multocida and Mycoplasma gallisepticum vaccines, for T-cell-mediated immunity evaluated by a phytohemagglutinin wing web assay, and for clearance of foreign particles from the circulatory system. Heritabilities of and genetic correlations among these immunological traits were calculated from the sire variance components. Heritability estimates of the immunological traits based on the sire component of variance ranged from .06 to .53, and genetic correlations among immunological traits were generally negative. PMID:1956847

1991-10-01

129

British Library Electronic Table of Contents (United Kingdom)

Chitosan (a?-(1-4)-amino-2-deoxy-b?-D-glucan) is a deacetylated form of chitin, a polysaccharide from crustacean shells. Its unique characteristics, such as positive charge, biodegradability, biocompatibility, nontoxicity, and rigid structure, make this macromolecule ideal for an oral vaccine delivery system. We prepared reverse-phase evaporation vesicles (REVs) sandwiched by chitosan (Chi) and polyvinylic alcohol (PVA). However, in this method, there are still some problems to be circumvented related to protein stabilization. During the inverted micelle phase of protein nanoencapsulation, hydrophobic interfaces are expanded, leading to interfacial adsorption, followed by protein unfolding and aggregation. Here, spectroscopic and immunological techniques were used to ascertain the effects ...

2011-01-01

130

Complete genome sequences of Brucella melitensis strains M28 and M5-90, with different virulence backgrounds.

Antigenic characterization of phocine distemper virus causing mass mortality in 2002 and its relationship to other morbilliviruses

Brucella melitensis is a Gram-negative coccobacillus bacteria belonging to the Alphaproteobacteria subclass. It is an important zoonotic pathogen that causes brucellosis, a disease affecting sheep, cattle, and sometimes humans. The B. melitensis strain M5-90, a live attenuated vaccine cultured from the B. melitensis virulent strain M28, has been an effective tool to control brucellosis in goats and sheep in China. Here we report the complete genome sequences of B. melitensis M28 and M5-90, strains with different virulence backgrounds, which will serve as a valuable reference for future studies. PMID:21478357

2011-04-08

131

British Library Electronic Table of Contents (United Kingdom)

Summary The antigenic relationship between the phocine distemper virus (PDV) strain causing the epidemic in 2002 and the PDV strain of 1988, canine distemper virus from two dogs and one marten, and one measles virus strain was investigated in vivo and in vitro using monospecific polyclonal and monoclonal antibodies directed against five different proteins of canine or phocine distemper virus (N, P, M, F, H). Epitopic mapping revealed no difference between the PDV strains causing the epidemics in 1988 or 2002. However, the use of these antibodies allowed discrimination between different morbilliviruses including a vaccine strain of canine distemper virus. The major differences among the investigated morbilliviruses were found in the H protein.

2007-01-01

132

SC Development Programme

Rhipicephalus sanguineus: vector of a new spotted fever group rickettsia in the United States.

SC Development Programme

1967-01-01

133

Protective efficiency of dendrosomes as novel nano-sized adjuvants for DNA vaccination against birch pollen allergy

A rickettsia related to but distinct from the spotted fever agent, Rickettsia rickettsii, has been detected in 167 (18.9%) of 884 Rhipicephalus sanguineus taken off dogs in central and northern Mississippi. The organisms could readily be isolated in male meadow voles (Microtus pennsylvanicus), where it produced massive infections in the tissues of tunica vaginalis. It was practically nonpathogenic for male guinea pigs, although inoculation of these animals with infected tunica vaginalis of voles afforded in 30 of 38 instances solid immunity to challenge with virulent R. rickettsii. The Rhipicephalus rickettsia grew well in monolayers of chicken embryo fibroblast, Vero, mouse L, and HeLa cells. Cytopathogenic effects were minimal unless large concentrations of rickettsiae were used as inocula. It also could be established in embryonated hen eggs but only after injection of massive doses of L cell-propagated organisms. Serological tests (complement fixation, microagglutination and/or ...

1975-07-01

134

British Library Electronic Table of Contents (United Kingdom)

We evaluated the use of a novel gene porter (Den123-a nontoxic self-assembled dendritic spheroidal nanoparticle made of biodegradable monomers), aiming to enhance and improve the desired immune response in protection from allergy. Footpad DNA immunization in Balb/c mice was done three times using the Bet v 1a gene with or without Den123 with 2-week intervals followed by sensitization with rBetv1 (5mg) in alum twice in a weekly interval. Different doses of pCMV-Betv1 were used (10mg and 100mg). The protective role of different formulations was evaluated by measuring the IgG1, IgG2a and IgE antibody production, cytokine release of isolated splenocytes and b-hexosaminidase release from the RBL cells. Higher and increasing ratios of IgG2a/IgG1 were seen in mice which received plasmids in combi...

2006-01-01

135

Hepatitis B immunization coverage and risk behaviour among Danish travellers Are immunization strategies based on single journey itineraries rational?

GAMMA GLOBULIN METABOLISM IN RABBITS DURING THE ANAMNESTIC RESPONSE.

OBJECTIVES: The authors examine the rationale and efficacy of pre-travel hepatitis B immunization strategies based on itinerary and presumed on-travel risk behaviour. METHODS: A large survey among 26,640 Danes survey provided data on journey lengths and destinations, immunization coverage, risk behaviour and knowledge. RESULTS: The estimated cumulative lifetime stay in endemic areas outside Europe is 4.3 months. The majority of risk situations are involuntary and unforeseeable. The majority of risk situations occur on short-term journeys. 5% nonimmune and 5% short-term travellers experienced at least one risk situation such as injections/operations/tattoos on their journey. The level of knowledge of hepatitis A and B is low. CONCLUSIONS: The rationale and efficacy of current immunization strategies are challenged. Based on the results presented here and the availability of vaccines with long-lasting coverage, the authors find that recommendations of immunization ...

2009-01-01

136

An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial

1. Gamma globulin metabolism and distribution were studied employing rabbit gamma globulin (RGG)I(131) 24 times in 13 control rabbits. Similar studies were performed before and during the ananmestic response in 4 rabbits previously sensitized with a polyvalent pneumococcal vaccine. 2. During the ananmestic response, gamma-globulin levels increased from 1.0 to 6.0 gm/100 ml, and the gamma-globulin pool increased from 0.7 to 4.7 gm/kg. There was no change in the intravascular-extravascular partition of gamma globulin. 3. Gamma globulin degradation increased from 0.06 to 0.33 gm/kg/day during the 28 days of the immunization period while gamma globulin synthesis increased even further to average 0.47 gm/kg/day. Following the attainment of elevated gamma globulin levels the fractional rate of RGG-I(131) turnover increased from 8.0 to 12.5 per cent/day. 4. No differences were noted in the metabolism of homologous or autologous gamma globulin regardless of the allotypic ...

1964-04-01

137

British Library Electronic Table of Contents (United Kingdom)

Summary Background Treatment of localised renal cell carcinoma consists of partial or radical nephrectomy. A substantial proportion of patients are at risk for recurrence because no effective adjuvant therapy exists. We investigated the use of an autologous, tumour-derived heat-shock protein (glycoprotein 96)-peptide complex (HSPPC-96; vitespen) as adjuvant treatment in patients at high risk of recurrence after resection of locally advanced renal cell carcinoma. Methods In this open-label trial, patients were randomly assigned to receive either vitespen (n=409) or observation alone (n=409) after nephrectomy. Randomisation was done in a one to one ratio by a computer-generated pseudo-random number generator, with a block size of four, and was stratified by performance score, lymph node stat...

2008-01-01

138

Software Development Tools Service

CERN Multimedia

Software Development Tools Service

1999-01-01

139

Software Development Tools Service

CERN Multimedia

Software Development Tools Service

1998-01-01

140

Software Development Tools Service

CERN Multimedia

Software Development Tools Service

1997-01-01

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141

A single amino acid substitution (R441A) in the receptor-binding domain of SARS coronavirus spike protein disrupts the antigenic structure and binding activity

Cryo-Optical Test Bed Development

The spike (S) protein of severe acute respiratory syndrome coronavirus (SARS-CoV) has two major functions: interacting with the receptor to mediate virus entry and inducing protective immunity. Coincidently, the receptor-binding domain (RBD, residues 318-510) of SAR-CoV S protein is a major antigenic site to induce neutralizing antibodies. Here, we used RBD-Fc, a fusion protein containing the RBD and human IgG1 Fc, as a model in the studies and found that a single amino acid substitution in the RBD (R441A) could abolish the immunogenicity of RBD to induce neutralizing antibodies in immunized mice and rabbits. With a panel of anti-RBD mAbs as probes, we observed that R441A substitution was able to disrupt the majority of neutralizing epitopes in the RBD, suggesting that this residue is critical for the antigenic structure responsible for inducing protective immune responses. We also demonstrated that the RBD-Fc bearing R441A mutation could not bind to soluble and cell-associated ...

2006-05-26

142

Indian Academy of Sciences (India)

Jan 22, 2004 ... Training and Professional Development Leadership Development Program. GSFC Leadership Development Program Positions. Cryo-Optical ...

143

Bioline International

- technology moving forward with new developments ...

144

Altering Sexual Development in Arabidopsis

Technology and Policy for Sustainable Development

Full Text Available

1998-06-01

145

Teacher Professional Continuum

The development of short-sea shipping will be fostered by the deployment of tracking and tracing systems,

146

Organizational structure and technology transfer

... efforts in developing and testing prototype materials or tools and Full Development Projects to ...

147

Magnetic forming coil design and development summary report

... administrative procedures developing countries economic development nuclear

1982-11-01

148

Estimating The Cost Of Developing Software

Magnetic forming coil design and development

1964-01-01

149

CZT Detector and HXI Development at CASS/UCSD

Software Cost Estimation Model program, SOFTCOST, developed to provide consistent automated

1991-01-01

150

Energy research and development. Ninety-Third Congress, First Session, December 1, 1973

CZT Detector and HXI Development at CASS/UCSD

2006-01-01

151

Instructional Materials Development Program

The Committee on Interior and Insular Affairs issued the report on a bill to establish a national program for research, development, and demonstration in fuels and energy and for the coordination and financial supplementation of Federal energy research and development; to establish development corporations to demonstrate technologies for shale oil development, advanced power cycle development, geothermal steam development, and coal liquefaction and gasification development; to authorize and direct the Secretary of the Interior to make mineral resources of the public lands available for the development conporations. Comments from governmental agencies on the bill are published. (MCW)

1973-01-01

152

Course and Curriculum Development Program, Evaluation Report

... Materials Development Program TECHNOLOGY EDUCATION INSTRUCTIONAL MATERIALS Elementary - High School ... of technology education materials through its Instructional Materials Development (IMD) program. The ...

153

The development of contemporary chiropractic education in Denmark: an exploratory study

... grants to adopt or adapt courses and materials developed by CCD projects at other institutions, and ... to adopt or adapt CCD-developed courses and materials. -iv- Accomplishments The CCD program has ...

154

Surface Decontamination by Solution

Udgivelsesdato: 2008-Oct

2008-01-01

155

Development of Technology for Metal Surface Decontamination in Aqueous Solutions

156

Safe climate

Review of the appropriateness of international assessment tools for a developing country

and develop markets for soy alternatives, such as lupins.14

157

CSIR Research Space (South Africa)

Full Text Available

158

Rap Signaling in Normal Lymphocyte Development and Leukemia Genesis

Molecular Genetics of Emericella nidulans Sexual Development

Full Text Available

2009-04-01

159

Lessons from Developing an Annotated Corpus of Patient Histories

Full Text Available

2009-09-01

160

Frequency Controlled Electric Drives

Full Text Available

2008-06-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

161

Effects of Licorice on Embryonic and Fetal Development in Rats

Development of Frequency Controlled Electric Drives

162

Development of the National Ecological Observatory Network (NEON)

Full Text Available

2005-12-01

163

Development of sup 203 Pb as a new label for monoclonal antibodies

Full Text Available

2007-02-01

164

Development of a Cost Effective Radio Communication System for UAS

Brief item.

1989-01-01

165

Development of Storage Management System for Small Dams

Full Text Available

2008-06-01

166

Development of Ceramic Body using Waste Celadon

Full Text Available

2005-05-01

167

Developing a national patient safety education framework for Australia.

Full Text Available

2009-11-01

168

Biological Surface-Active Substance

PMID:17142595

2006-12-01

169

Probabilistic Simulation for Nanocomposite Characterization Developed and Included in the Computer Code ICAN/JAVA

Development of biological preparation with surfactant activity

170

Hydrothermal industrialization electric-power systems development. Final report

A unique mechanistic method has been developed at the NASA Glenn Research Center to

2008-01-01

171

Electron-induced luminescence and x-ray spectrometer development: progress report

The nature of hydrothermal resources, their associated temperatures, geographic locations, and developable capacity are described. The parties involved in development, required activities and phases of development, regulatory and permitting requirements, environmental considerations, and time required to complete development activities ae examined in detail. These activities are put in proper perspective by detailing development costs. A profile of the geothermal industry is presented by detailing the participants and their operating characteristics. The current development status of geothermal energy in the US is detailed. The work on market penetration is summarized briefly. Detailed development information is presented for 56 high temperature sites. (MHR)

1982-03-01

172

Development of a Colony of Germfree Hamsters as a ...

The progress in the development of a surface analysis tool based on the excitation of characteristic

2003-01-01

173

Development of QTL Mapping Populations

... Accession Number : ADA021166. Title : Development of a Colony of Germfree Hamsters as a Biomedical Resource. Descriptive Note : Final rept. ...

1976-01-07

174

DEVELOPMENT OF A MANUFACTURING PROCESS AND ...

The objective of this animation is to develop a QTL mapping population for locating and characterizing the genes responsible for resistance to tan spot disease of wheat.

175

Development Application - Terra Nova Development - Supplement B to the Application

... This work was based upon previously successful development of combustible cartridge cases, at Illinois Institute of Technology Research Institute ...

1968-05-01

176

Coal development potential in Pakistan

Supplement B to the Terra Nova Development Application provides a description of the floating production storage and offloading (FPSO) vessel system selected for the development, a summary of the reasons for selecting the system, and the impact of this selection on the Development Plan, the Benefits Plan, the Environmental Impact Statement and the Socio-Economic Impact Statement. There is also a description of the contractor alliance approach to be used in the Terra Nova Development. Refs., tabs., figs.

1997-02-01

177

Practical MRI atlas of neonatal brain development

A total of 48 papers were presented, and covered the following topics: the current situation in Pakistan with respect to development and utilization of coal resources; the policies that have been responsible for the development and utilization of coal resources in Pakistan; coal development and utilization in other developing nations e.g. Indonesia, Greece, Philippines, China, Thailand and Haiti; and technological developments in coal exploration; extraction, handling, transport and utilization which could accelerate future development of Pakistan's coal resources. Specific subjects covered include the use of coal in the cement industry of Pakistan; the production of briquettes for domestic use, development and training of personnel for the coal industry; and sources of finance for coal development projects. ...

1986-01-01

178

Water Deficit and Spatial Pattern of Leaf Development. Variability in Responses Can Be Simulated Using a Simple Model of Leaf Development1

This book is an anatomical reference for cranial magnetic resonance imaging (MRI) studies in neonates and infants. It contains 122 clear, sharp MRI scans and drawings showing changes in the normal appearance of the brain and skull during development. Sections of the atlas depict the major processes of maturation: brain myelination, development of the corpus callosum, development of the cranial bone marrow, and iron deposition in the brain. High-quality scans illustrate how these changes appear on magnetic resonance images during various stages of development.

179

Using the Java language to develop computer based patient records for use on the Internet.

We analyzed the effect of short-term water deficits at different periods of sunflower (Helianthus annuus L.) leaf development on the spatial and temporal patterns of tissue expansion...Full Text Available

1999-02-01

180

Sex and Hormonal Variations in the Development of At-level Allodynia In a Rat Chronic Spinal Cord Injury Model

The development of the Java Programming Language by Sun Microsystems has provided a new tool for the development of Internet based applications. Our preliminary work has shown how Java can be used to...Full Text Available

1996-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

181

Sandia microelectronics development

The development of central neuropathic pain varies among patients with spinal cord injury (SCI). The factors contributing to the development and perpetuation of segmental pain (at-level allodynia)...Full Text Available

2010-06-25

182

Safety culture development at Daya Bay NPP

An overview of the operations of Sandia`s Microelectronics Development Lab (MDL) is to develop radiation hardened IC, but techniques used for IC processing have been applied to a variety of related technologies such as micromechanics, smart sensors, and packaging.

1997-02-01

183

Renewable energy and the ODA energy efficient strategy

From view on Organization Behavior theory, the concept, development and affecting factors of safety culture are introduced. The focuses are on the establishment, development and management practice for safety culture at Daya Bay NPP. A strong safety culture, also demonstrated, has contributed greatly to improving performance at Daya Bay

2001-12-01

184

Recent Developments in Coal Liquefaction at the Wilsonville Advanced Coal Liquefaction Research and Development Facility.

The energy strategy of the UK Overseas Development Administration is outlined with specific emphasis on energy efficiency and renewable energies. Based on 29 case studies concerning projects and programmes in both developed and developing countries, critical success factors for renewable energy projects are identified. UK)

1995-12-31

185

Effect of Surgical Alteration of the Rat Gastrointestinal Tract On the Growth and Development of Hymenolepis Diminuta

The results of the two most recently completed runs at the Wilsonville Advanced Coal Liquefaction Research and Development Facility are presented. In Run 255, initial screening of operating conditions for the liquefaction of a Texas lignite was completed....

1991-01-01

186

The ''Complex Reality'' of Research Capacity Development in Mathematics Education in Southern African Development Community Countries

... Gastrointestinal Tract On the Growth and Development of Hymenolepis DiminutaKerry L. Dwinell, Paul Bass, Gordon L. Telford, ... central (CNS) nervous systems in the development of Hymenolepis diminuta usi...

187

Traumatic retinal detachment.

This paper explores how an aid-funded Ph.D.-programme in mathematics education instituted in some Southern African Development Community countries measures up to issues related to research capacity development projects. The research capacity development programme is described and reflected against mutual benefit, relevance, sustainability and prioritization of the location of project funding expenditure--some of the constructs in the discourse on research capacity development initiatives. It is found that the benefits of the programme are indeed mutual; the outcomes regarding relevance and sustainability are more uncertain and the location of expenditure of the funding is not overtly in favour of the donor country.

2005-11-01

188

The mammalian oocyte orchestrates the rate of ovarian follicular development

Seventy-seven patients developed retinal breaks following an episode of ocular contusion, and 65 (84.4%) of these developed rhegmatogenous retinal detachment. Surgical treatment successfully restored...Full Text Available

1991-01-01

189

The Development of a Dental Diagnostic Terminology

The development of both the mammalian oocyte and the somatic cell compartments of the ovarian follicle is highly coordinated; this coordination ensures that the ovulated oocyte is ready to undergo fertilization...Full Text Available

2002-03-05

190

Symbiotic regulation of plant growth, development and reproduction

There is no commonly accepted standardized terminology for oral diagnoses. The purpose of this article is to report the development of a standardized dental diagnostic terminology by a work...Full Text Available

2011-01-01

191

Strategic Communication: A Department of Defense Approach

The growth and development of rice (Oryzae sativa) seedlings was shown to be regulated epigenetically by a fungal endophyte. In contrast to un-inoculated (nonsymbiotic) plants, endophyte...Full Text Available

2009-03-01

192

R/V Laurence M. Gould LMG0303 - Development of a luminescence - NASA

... development of SC policy within DOD, because it describes the necessary link between DOD ... strategy convolutes USG efforts to develop SC policy. ...

2007-03-28

193

Probiotic Bacteria as Biological Control Agents in Aquaculture

R/V Laurence M. Gould LMG0303 - Development of a luminescence dating capability for Antarctic glaciomarine sediments: Tests of signal zeroing at the ...

194

Meeting the resistance problem

There is an urgent need in aquaculture to develop microbial control strategies, since disease outbreaks are recognized as important constraints to aquaculture production and trade and since the development...Full Text Available

2000-12-01

195

In Defense of Change Processes

Because resistance to new insecticides may develop rapidly and cross resistance is often encountered, even between insecticides of different classes, there is a continual demand for the development...Full Text Available

1963-01-01

196

Hypothyroidism Enhances Tumor Invasiveness and Metastasis Development

Nativist and constructivist approaches to the study of development share a common emphasis on characterizing beginning and end states in development. This focus has highlighted the question...Full Text Available

2008-01-01

197

High-Temperature Solar Cell Development - GLTRS - NASA

BackgroundWhereas there is increasing evidence that loss of expression and/or function of the thyroid hormone receptors (TRs) could result in a selective advantage for tumor development,...Full Text Available

198

Environmental estrogens alter early development in Xenopus laevis.

High-Temperature Solar Cell Development. Geoffrey A. Landis,. NASA John Glenn Research Center. 21000 Brookpark Road, Cleveland, OH 44135. Danielle ...

199

Electron-induced luminescence and x-ray spectrometer development

A growing number of environmental toxicants found in pesticides, herbicides, and industrial solvents are believed to have deleterious effects on development by disrupting hormone-sensitive processes....Full Text Available

2003-04-01

200

Development of grid-connected photovoltaic systems

Jan 22, 2011 ... dc.description.abstract, The progress in the development of a surface analysis tool based on the excitation of characteristic luminescence ...

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

201

Development of a universal plate-agglutination test for detecting Haemophilus parasuis

The activities and the policy in the Netherlands regarding the development of the title systems since 1990 are briefly outlined, focusing on the use of PV-systems in buildings. 5 figs., 1 tab.

202

Development of a Long-Range Gliding Underwater Vehicle ...

Due to the serovar diversity in Haemophilus (H.) parasuis, it is difficult to develop a universal serological method for detection of this pathogen....Full Text Available

2010-12-01

203

Development of a FeCoNb Alloy to be used in Eddy Current ...

... investigates the convergence of three main areas of UUV development; mission ... with an improved low-cost embedded-system robot controller, to ...

2008-09-01

204

Development of High Field Dipole and High Current Pulse Power Supply for Compact Proton Synchrotron

... Accession Number : ADD336001. Title : Development of a FeCoNb Alloy to be used in Eddy Current Probes for Testing Ferromagnetic Tubes,. ...

205

Development of Grade API X80 Pipeline Steel Plates ...

Development of High Field Dipole and High Current Pulse Power Supply for Compact Proton Synchrotron

2003-01-01

206

Develop Magnetic Coil Design and Manufacturing Capability.

... Accession Number : ADD130998. Title : Development of Grade API X80 Pipeline Steel Plates Produced by Controlled Rolling,. Corporate Author : ...

207

Course, Curriculum, and Laboratory Improvement (CCLI)

... design, and manufacturing knowledge have been acquired and used to develop an 'in-house' capability for the fabrication of magnetic forming coils ...

1974-11-01

208

Copper deficiency alters the neurochemical profile of developing rat brain

... teaching and learning; Creating learning materials and teaching strategies; Developing faculty ... achieve educational innovations. Educational Materials Development (EMD): A project under the former ...

209

Advanced Technological Education Program: 1999 Awards and Activities

Copper deficiency is associated with impaired brain development and mitochondrial dysfunction. Perinatal copper deficiency was produced in Holtzman rats. In vivo proton NMR...Full Text Available

2009-06-01

210

[Transurethral resection in saline (TURis): a newly developed TUR system preventing obturator nerve reflex].

... By developing and disseminating educational materials and curricula, supporting the preparation and ... education, such as curriculum or educational materials development, faculty or teacher preparation ...

211

[Development of Eurytrema pancreaticum (Janson, 1889) (Trematoda: Dicrocoeliidae) in the Maritime Territory].

PMID:14671997

2003-11-01

212

Treating disaster as a development opportunity : a study of earthquake recovery in Sichuan

PMID:4786633

213

Norwegian Open Research Archives (NORA)

Full Text Available

214

The beaver's reconquest of Eurasia: status, population development, and management of a conservation success

Norwegian Open Research Archives (NORA)

Full Text Available

215

The Economic Impacts of Pacific Ocean Deep-sea Manganese Nodule Development Project

Sustainability Network Letter 60E

Full Text Available

2010-12-01

216

Study on the Development of Solid Fuel of Animal Wastes for Heating of Agricultural Facilities

crucial to the survival of our species that our brains have developed an obsession with all things

217

Sheath development around a high voltage cathode in a glow discharge plasma

Full Text Available

2007-10-01

218

Secondary Titanium Processes

Short communication. 3 refs.

1991-02-04

219

Screening of Medicinal Plants for Development of Functional Food Ingredients with Anti-Obesity

Research and Development of Resource-Saving Technology for Manufacturing of Titanium Semifinished Items from Chips

220

Full Text Available

2006-09-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

221

Rubomycine Production

Review for free electron laser (FEL) development

Development of Experimental Large-scale Technology and Creation of Technological Line of Rubomicine Production

222

Radiation and fetal brain development

The authors have analysed the technical character of FEL, estimated its present status, developing trend and application prospect at home and abroad. Meanwhile the have also reviewed the significance of developing FEL, its position, role and difficulties. Finally the have presented some suggestions for FEL future developments in China.

223

Radial Halbach Magnetic Bearings

(4 Sep 1986). United Kingdom Zamenhof, Stephen . California Univ., Los

224

Radial Halbach magnetic bearings have been investigated as part of an effort to develop increasingly

2009-01-01

225

Pure Scandium Production

Porting to the Symbian Platform Open Mobile Development in C/C++

Development of the Technology to Obtain Pure Metal Scandium by Thermal Decomposition of Scandium Iodide

226

Planning and Operation of Commercial Application Center

Porting to the Symbian Platform

2009-01-01

227

Parallel expression of synaptophysin and evoked neurotransmitter release during development of cultured neurons

The objectives of this R and D project are as follows : First, transferring developed technologies to outside companies and operating technology market to vitalize technology transactions, Second, developing commercial application projects to transfer technologies for commercial purposes and to solve interface problems in commercial applications, Third, enhancing commercial utilizations of developed accelerator and beam utilization technologies, Finally. preparing infra-structures for the development of over 30 venture- businesses based on achieved technologies through the Proton Engineering Frontier Project.

2003-06-15

228

Oxygen Implanted Materials

Udgivelsesdato: 1991-null

1991-01-01

229

Online monitoring of pollen - development of a novel technique and first results of field experiments

Development of Oxygen Ion-Implanted Collector materials for Thermal Emission Converters of Thermal Energy into the Electric One.

230

On the Relationship between Typhoon Intensity and Formation Region: Effect of Developing and Decaying ENSO

No abstract prepared.

2005-07-01

231

Numerical investigation on developing laminar forced convective heat transfer and entropy generation in an annular helicoidal tube

Full Text Available

2008-02-01

232

Newly developed control and stop valves

Full Text Available

2011-06-01

233

... bwr type reactors closures fluidic control devices operation performance pwr

234

New Effective Pesticides

Nanomachines: How Viruses Work, and How We Can Stop Them

Development the New Effective Pesticides in the Series of Pyrimine and Sym-Triazine Derivatives

235

ScienceCinema

...the development of biomedicine ...

236

N7'5 20853

MICROSEISMICS AND GEOTECHNICAL APPLICATIONS

of fracture -stimulated geothermal reservoirs; 2) the development of ... of the mathematical simulation model of geothermal reservoirs. ...

237

Low-Temperature Neon Isotope Separation

... PRODUCTION OF TIGHT OIL-GAS BEARING ROCKS, AND IS ALSO EMPLOYED FOR THE DEVELOPMENT OF GEOTHERMAL RESERVOIRS. ...

1989-06-01

238

Investigations and development of gaseous radiation detectors; Badania i rozwoj konstrukcji gazowych detektorow promieniowania

Development of a Plant for Neon Isotopes Separation by Low-Temperature Rectification Method

239

No abstract prepared

1998-12-31

240

Inside - NASA

Inhibitory Activity of Advanced Glycation Endproducts (AGE) Formation of Edible Plants for Development of Anti-Wrinkle Ingredients

developed for our government and industrial robots were used by .... UUV capabilities, into a product. The licensing agreement and ...

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

241

Full Text Available

2010-02-01

242

India cleans up

Immunohistochemical expression of p63 in human prenatal tooth primordia

The paper discusses clean coal technology developments in India. 2 photos.

2011-01-15

243

Hudson Lecture for 1958 Darwinism in New Zealand: Some Examples, Influences and Developments

development, histochemical, human, malformation, p63 gene, tooth

2005-01-01

244

Transactions and Proceedings of the Royal Society of New Zealand 1868-1961

Full Text Available

1959-01-01

245

High-Performance SPICE Development Including an Analytical Transient Photocurrent BJT Model

FY2003 Laboratory Directed Research and Development Program Annual Report

No abstract prepared.

2000-08-01

246

Expression of microtubule associated protein of low molecular weight (TAU) in mouse brain development

No abstract prepared.

2004-07-30

247

Evaluation on corrosion environment at BWRs

Published in summary form only.

248

Environmental and resource economics in South Africa: status quo and lessons for developing countries

... Systems Research and Development Center, Yokohama, Kanagawa (Japan)

2009-05-01

249

CSIR Research Space (South Africa)

Full Text Available

250

Entomopathogenic Nematodes in Biological Control

Electrodepositing Nanostructured Composite Coatings

Commercial Production and Development, in Entomopathogenic Nematodes in Biological Control

251

Electrochemical Solar Energy Converter

Development of the Method of Electrodepositing Nanostructured Composite Coatings with Improved Engineering Properties

252

Effects of Concrete and Wood Building Environments on Pregnant Dams and Embryo-Fetal Development in Rats

Elaboration of Electrochemical Solar Energy Converter Incorporating Cadmium Selenide Semiconductor Developed Electrochemically

253

Effect of Low Night Temperature on Reproductive Organ Development in Relation to Pollen Viability of Bell Pepper

Full Text Available

2009-12-01

254

Education for Development in Underdeveloped Countries.

Full Text Available

2009-05-01

255

Ecologically Safe Luminescent Lamps

Past "elitist" development efforts modeled on Western academic education have failed to meet manpower needs but resist change due to popular preference for "modern" occupations. A new development strategy providing universal basic education and improved general living standards is needed. (Part of a theme issue on Third World educational development.) (SJL)

1981-06-01

256

Development of the Calorimeter to Measure Heat Rate Generated from Battery for EV & HEV

Development and Creation of Model Samples of Ecologically Safe Luminescent Lamps

257

Development of the Caliper System for a Geometry PIG Based on Magnetic Field Analysis

Full Text Available

1999-11-01

258

Development of the Automative Correction System for the Digital Over-current Relay With Distribution System

Full Text Available

2003-12-01

259

Development of coal utilization technology in the Japanese steel industry - co-operation with coal suppliers

Full Text Available

2007-04-01

260

Development of chemical separation in gas phase for heavy actinide and trans-actinide elements

Past and current development of coal utilization technology in the Japanese steel industry is reviewed and some projects currently under research and development briefly described. These include DIOS, an iron making process which directly utilizes both iron ore and coal without a sintering plant or a coke oven; and the development of a new generation coke oven. 15 figs.

1994-12-31

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

261

Development of an Active Magnetic Noise Shielding System for a Permanent Magnet Based MRI

No abstract prepared

1998-01-01

262

Development of a hardware in the loop simulation system for electric power steering in vehicles

Full Text Available

2003-05-01

263

Development of a fiber coupled, end pumped, Nd:YAG laser spark plug

Full Text Available

264

Development of a dual serial-parallel multiphase CFD code for application to industrial combustor/reactor systems.

None provided

2007-09-01

265

Development of a Wireless Vibration Monitoring System for Structural Health Evaluation

No abstract prepared.

2000-05-16

266

Development of a Standard Data Base and Computer ...

Full Text Available

2010-02-01

267

Development of Small-sized Gas Turbine Engine Control System for Power Generation

... (Author). Descriptors : (*TERMINAL FLIGHT FACILITIES ... PROGRAMMING, HANDLING), QUEUEING THEORY, STOCHASTIC PROCESSES ...

1973-01-01

268

Development of Single-Frame PIV Velocity Field Measurement Technique Using a High Resolution CCD Camera

Full Text Available

2011-08-01

269

Development of Regional Noodles Using Agricultural and Fishery Products of Cheju Island

Full Text Available

2000-01-01

270

Development of National Life Cycle Inventory Database on Irrigation Water by Agricultural Dam

Full Text Available

1996-08-01

271

Development of Multi-layer Electromagnetic wave Absorbers Using Sendust

Full Text Available

2011-05-01

272

Development of Location Estimation and Navigation System of Mobile Robots Using USN and LEGO Mindstorms NXT

Full Text Available

2006-10-01

273

Development of Lightweight Moving Table for Linear Motor using Composite Materials

Full Text Available

2010-03-01

274

Development of Estimation Model for Hysteresis of Friction Using Artificial Intelligent

Full Text Available

2010-04-01

275

Development of Broadband Electromagnetic Wave Absorber for X-band Sensors in Double-layered Type Using Carbon

Full Text Available

2011-07-01

276

Development and Fabrication of Compositions for 155-mm ...

Full Text Available

2006-12-01

277

Development and Evaluation of an e-Learning Program for Mothers of Premature Infants

... Descriptors : *PROPELLING CHARGES, *NITROCELLULOSE, *COMBUSTIBLE CARTRIDGE CASES, DENSITY, FIBERS, MANUFACTURING ...

1982-10-01

278

Development an Empirical Formula for the Friction Coefficient of a Circular Friction Damper

Full Text Available

2008-02-01

279

Degradation of leucine zipper-positive isoform of MYPT1 may contribute to development of nitrate tolerance.

Full Text Available

2011-06-01

280

DEVELOPMENT OF THE PILOT WARNING INSTRUMENT ...

PMID:19939965

2009-11-25

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

281

Corrosion Protection of special steels and alloys

... multivibrators and amplifiers arranged to operate as described above. ... The first of the multivibrators is triggered by the trailing edge of the ...

1962-02-01

282

Continuous Strategy Development for Effects-Based ...

Development of the Corrosion Protection Technology for Special Steels and Alloys

283

Combustion of Crop Production Wastes

... BAE Systems Advanced Information Technologies, Inc. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. ...

2006-02-01

284

Chemical Reactor Diagnostics

Development, Investigation and Improvement of a System of Incinerating Crop Production Wastes in Small Capacity Boilers

285

Ceramic Composite Materials

Development of Methods and Apparatus for Processes Diagnostics in Plasma Reactors at the Neutralization of Chemical Herbiside and Pestiside

286

Boron-10 Materials Production

Development of Ceramic Composite Materials and Structural Elements for High-Temperature Nuclear Reactors

287

Biology-inspired Architecture for Situation Management

Development of Technologies for Boron-10 Isotope Modified Boron-containing Materials Production and their Properties Investigation.

288

Automated transport and sorting system in a large reference laboratory: part 1. Evaluation of needs and alternatives and development of a plan.

Situation Management is a rapidly developing science combining new techniques for data collection

2006-01-01

289

Antimicrobials in the Management of Post-Irradiation Infection

PMID:12324492

2002-10-01

290

A Study on Development of Electro Magnetic Wave Absorbers for Mobile Phones

... develops. An alternative approach is the use of non-absorbable antibiot- ics such as polymyxin, neomycin, and bacitracin. ...

2011-05-13

291

A Study of Magnetic Properties for Recycling of Laser Printer Developer Roller

Full Text Available

2006-05-01

292

A Report on the Evaluation of the NSF's Informal Science Education (ISE) Program

Full Text Available

2009-01-01

293

A Development of Visualization Software for Protective Engineering in Low-Voltage Power Systems

... science in places outside of schools, with materials and activities initially not developed for ...

294

Web-Based Enterprise Information Systems Development: The Integrated Methodology

Full Text Available

2006-07-01

295

Energy requirements for rural development

The paper considers software development issues for large-scale enterprise information systems (IS) with databases (DB) in global heterogeneous distributed computational environment. Due to high IT development rates, the present-day society has accumulated and rapidly increases an extremely huge data burden. Manipulating with such huge data arrays becomes an essential problem, particularly due to their global distribution, heterogeneous and weak-structured character. The conceptual approach to integrated Internet-based IS design, development and implementation is presented, including formal models, software development methodology and original software development tools for visual problem-oriented development and content management. IS implementation results proved shortening terms and reducing costs of implementation compared to commercial software available.

2006-01-01

296

Safeguards and Security Technology Development Directory. FY 1993

This study on the role of energy in the development of rural areas was originally conducted in the spring and summer of 1985. It was intended to serve as a background paper for the preparation of a program plan for the Office of Energy of the United States Agency for International Development. As such it begins with a brief overview of how rural development fits into national development, then offers a comprehensive framework for thinking about rural development in particular and the energy implications of the various components of rural development. Agriculture naturally comes to mind when rural areas are mentioned, but industry is an important component of rural activity as well. Consequently, both agricultural and nonagricultural energy use is discussed. Modernization of rural areas will change household, as well as production, energy use. However, household ...

1988-06-01

297

Guide to good practices for the development of test items

The Safeguards and Security Technology Development Directory is published annually by the Office of Safeguards and Security (OSS) of the US Department of Energy (DOE), and is Intended to inform recipients of the full scope of the OSS R&D program. It is distributed for use by DOE headquarters personnel, DOE program offices, DOE field offices, DOE operating contractors, national laboratories, other federal agencies, and foreign governments. Chapters 1 through 7 of the Directory provide general information regarding the Technology Development Program, including the mission, program description, organizational roles and responsibilities, technology development lifecycle, requirements analysis, program formulation, the task selection process, technology development infrastructure, technology transfer activities, and current research and development tasks. These chapters are followed ...

1993-06-01

298

The relationship between reclamation and sustainable economic development

While the methodology used in developing test items can vary significantly, to ensure quality examinations, test items should be developed systematically. Test design and development is discussed in the DOE Guide to Good Practices for Design, Development, and Implementation of Examinations. This guide is intended to be a supplement by providing more detailed guidance on the development of specific test items. This guide addresses the development of written examination test items primarily. However, many of the concepts also apply to oral examinations, both in the classroom and on the job. This guide is intended to be used as guidance for the classroom and laboratory instructor or curriculum developer responsible for the construction of individual test items. This document focuses on written test items, but includes information relative to ...

1997-01-01

299

Creative activity in conception of sustainable development education

The purpose is to define sustainable economic development in the context of nonrenewable resources and to examine the changing nature of reclamation over time. Sustainable development is development that ensures the present utilization of resources and the environment does not damage prospects for their use by future generations. Polls show that the public is demanding higher environmental standards. One mechanism for achieving sustainable economic development for the nonrenewable resource sector is through reclamation. The Alberta government`s approach to reclamation is reviewed to show how reclamation and sustainable government are linked together. The history of reclamation legislation in Alberta is summarized. 10 refs.

1991-06-01

300

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to reflect on the stages in the development of creative activity considering the distinctive features of all stages and the modes of dynamics of the development of a creative person. Design/methodology/approach - The paper analyses scientific investigations and pedagogical experiences in order to develop the model for the formation of creative activity of artists-visual art teachers in the context of sustainable development. Findings - The investigations of scientific literature on pedagogy, psychology, philosophy, as well as the analysis of pedagogical practice allow us to recognize that the formation of creative activity is comprised of several stages. These stages are closely connected with a creative process and depend on a person's artistic talen...

2007-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

301

Toxic effects of lead on neuronal development and function

Sequential development of correlated projects: an application to coal liquefaction

The effects of lead on the development of the nervous system are of immediate concern to human health. While it is clear that lead can affect neuronal development at levels of exposure within the range found in the environment, the particular mechanism of the disruption is not readily ascertained. The goal of the authors research is to develop a model system in which the effects of lead on central nervous system development can be demonstrated. To study neuronal development in a system that minimizes such difficulties, the authors have grafted discrete brain regions derived from rat fetuses into the anterior chamber of the eye of adult hosts. The brain pieces continue organotypic development in the eye, but are isolated from possible secondary changes due to alterations in the development of the endocrine and other somatic systems because ...

1990-11-01

302

Organizational model of control of state of technology in the coal industry

A sequential research and development programme is considered for which several categories of related technologies are available to develop, each having the potential to produce some final product. At each stage of the programme, an optimal portfolio of technologies is chosen given the information acquired from the previous stages, and those contingent optimal plans are followed in all subsequent stages. The model is applied to coal liquefaction technologies to emphasize the costs that may be incurred by erroneously approaching the development programme as a once-and-for-all endeavour rather than in a sequential framework. The results of the synthetic oil application indicate that the acceleration of the programme may be optimal when the probability of successful development decreases. Under these conditions, adoption of a 'crash programme' in which all projects are researched ...

1983-01-01

303

Development of in-vessel reflood instrumentation at ORNL

This paper discusses organizational models of planning technology development in coal mining. The following 4 planning systems are analyzed: all-union national system coordinated by the Ministry of Coal Mining of the USSR, all-union associations of coal mine associations (in the Ukrainian SSR the plan is developed by the Ministry of Coal Industry of the Republic), associations of coal mines, coal mines or groups of coal mines. Methods for developing programs for technology development at 4 levels are reviewed. The following planning periods are used: 10 years or more (from 1980 to 1990), a 5 year period and a 1 year period. System for technology development in the Soviet coal industry from 1981 to 1985 is evaluated: research and development programs (20 comprehensive state programs, 36 branch programs). (In Russian)

1984-02-01

304

Development of Control Design Scheme Using Nonlinear Analysis

A program under the sponsorship of the United States Nuclear Regulatory Commission was intiated at the Oak Ridge National Laboratory (ORNL) in late 1977. The program, Advanced Instrumentation for Reflood Studies (AIRS), is charged with developing instrumentation for measurement of in-vessel fluid phenomena in pressurized water reactor reflood facilities. The goal of the ORNL program is to develop techniques and systems for measuring fluid flow in-core, deentrainment in the upper plenum and liquid fallback from the upper plenum into the core. A large portion of the development at ORNL is devoted to the impedance probes for measurement of two-phase flow velocities and void fractions. Film probe development at ORNL is limited to adapting the present techniques to the environment of a reflood facility. As the development progresses on all the measurement techniques, ORNL will fabricate ...

2004-09-06

305

Virtual adult ears reveal the roles of acoustical factors and experience in auditory space map development

Phenomena in power systems tend to exhibit higher nonlinearity, because efficient operation accompanies severer power transfer. In such cases, there might exist some limitation to the use of conventional linear control design scheme due to the nonlinearity. As for consideration to the nonlinearity, we have developed a nonlinear analysis method based on normal form theory. In this paper, we develop a new control design scheme based on the nonlinear analysis method. The developed method is effective in a case when oscillatory instability occurs. In the developed method, the parameters of control devices are adjusted so as to enlarge the stability limit against the oscillatory instability, unless each eigenvalue exceed its allowable threshold. We verify the effectiveness of the developed method in the IEEJ 10-machine System Model by applying to PSS (Power System Stabilizer). We show ...

2007-01-01

306

Uneven dietary development: linking the policies and processes of globalization with the nutrition transition, obesity and diet-related chronic diseases

Auditory neurons in the superior colliculus (SC) respond preferentially to sounds from restricted directions to form a map of auditory space. The development of this representation is shaped...Full Text Available

2008-11-05

307

Undergraduate Course and Curriculum Development Program and Curriculum Development in Mathematics: Calculus and the Bridge to Calculus 1994 Awards

In a "nutrition transition", the consumption of foods high in fats and sweeteners is increasing throughout the developing world. The transition, implicated in the rapid rise of obesity and diet-related...Full Text Available

308

The development and validation of the daily electronic Endometriosis Pain and Bleeding Diary

... such as biology, physics, geology, materials science, engineering, computer science, and mathematics ... expected to produce course and curricular materials that will be of national interest and widely ...

309

The Role of Thyroid Hormone in Testicular Development and Function

BackgroundThe objective of this study was to develop and validate a daily electronic Endometriosis Pain and Bleeding Diary (EPBD) for assessing treatment-related changes in endometriosis...Full Text Available

310

The Notochord, Notochordal cell and CTGF/CCN-2: ongoing activity from development through maturation

Thyroid hormone is a critical regulator of growth, development and metabolism in virtually all tissues, and altered thyroid status affects many organs and systems. Although for many years testis...Full Text Available

2008-12-01

311

Terminal-differential algorithm for identification of local non homogeneity in article

The growth regulating factor CTGF/CCN-2 is an integral factor in growth and development, connective tissue maintenance, wound repair and cell cycle regulation. It has recently been reported that CTGF/CCN-2...Full Text Available

2008-12-01

312

Research and development for the upgrading of Rhenish brown coal

Terminal-differential algorithm for identification of local nonhomogeneities in items under control is developed on the basis of measurements of X-ray or gamma-radiation weakening. The algorithm may be applied by developing radiation schemes of nondestructive control, identifying inadmissible inclusions in the object under study

313

Rapid Onset of Maternal Vocal Recognition in a Colonially Breeding Mammal, the Australian Sea Lion

Product control procedures, the development of new technologies, and the extension of the applications of solid fuels are described. Hydrogasification and high-temperature Winkler gasification are discussed. The design and function of a continuous, semi-industrial plant for hydrogenating liquefaction in the sump phase are gone into. (MOS).

1988-07-01

314

REM Sleep Percentage in Children with Autism Compared to Children with Developmental Delay and Typical Development

BackgroundIn many gregarious mammals, mothers and offspring have developed the abilities to recognise each other using acoustic signals. Such capacity may develop at different rates...Full Text Available

315

Propranolol ameliorates the development of portal-systemic shunting in a chronic murine schistosomiasis model of portal hypertension.

ObjectiveTo compare objective polysomnographic parameters between three cohorts: children with autism, with typical development, and with developmental delay without...Full Text Available

2010-11-01

316

Proof-of-concept Design and Development of an EN13606-based Electronic Health Care Record Service

We investigated the role of early portal hypotensive pharmacotherapy in preventing the development of portal-systemic shunting in a portal hypertensive model of chronic murine schistosomiasis induced...Full Text Available

1991-03-01

317

Progress report on negative ion beams based on User Development Workshop on negative ion based neutral beams, 15-16 February, 1983, Princeton

ObjectiveThe authors present an Electronic Healthcare Record (EHR) server, designed and developed as a proof of concept of the revised prEN13606:2005 European standard concerning...Full Text Available

2007-01-01

318

Pattern formation and traveling waves in myxobacteria: Theory and modeling

Progress in the development of negative ion sources and their application in fusion research is reviewed. (U.K.).

1983-04-18

319

PDP-1 Links the TGF-? and IIS Pathways to Regulate Longevity, Development, and Metabolism

Recent experiments have provided new quantitative measurements of the rippling phenomenon in fields of developing myxobacteria cells. These measurements have enabled us to develop a mathematical model...Full Text Available

2001-12-18

320

Numerical Weather Prediction Activities Report.

The insulin/IGF-1 signaling (IIS) pathway is a conserved regulator of longevity, development, and metabolism. In Caenorhabditis elegans IIS involves activation of DAF-2 (insulin/IGF-1...Full Text Available

2011-04-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

321

Nuclear raw materials: Developing resources through technical co-operation

This report presents a summary of highlights of the year 1978. It then discusses: Research and development in numerical analysis and prediction systems; Techniques, development and application of new products; Analysis-forecast systems in operation use du...

1978-01-01

322

Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins.

This article presents an overview of the IAEA's technical co-operation activities in the field of nuclear raw materials, particularly looking at recent developments and trends influencing future directions

1993-09-01

323

Malate- and Pyruvate-Dependent Fatty Acid Synthesis in Leucoplasts from Developing Castor Endosperm 1

In our quest for novel genes required for the development of the embryonic peripheral nervous system (PNS), we have performed three genetic screens using MAb 22C10 as a marker of terminally differentiated...Full Text Available

2000-12-01

324

Localisation of glycoproteins and glycosaminoglycans during early eye development in the macaque.

Leucoplasts were isolated from the endosperm of developing castor (Ricinis communis) endosperm using a discontinuous Percoll gradient. The rate of fatty acid synthesis was highest...Full Text Available

1992-04-01

325

Investigation of the semicrystalline morphology development in polymeric blends of thermoplastic polyesters, PET/PBT and PET/PC, through optical microscopy development, DSC and SAXS/WAXD/DSC with synchrotron radiation

The composition of the extracellular matrix (ECM) was examined in the developing lens and optic cup (stages 11-16) of the long-tailed monkey (Macaca fascicularis) using peroxidase immunocytochemistry....Full Text Available

1995-02-01

326

Intensity modulated radiotherapy: advantages, limitations and future developments

Portuguese 2007 p. 136 Brazil Barbosa Junior, IB Larocca, NM Hage Junior,

2007-02-12

327

Insulin receptor signaling in the development of neuronal structure and function

Intensity modulated radiotherapy (IMRT) is widely used in clinical applications in developed countries, for the treatment of malignant and non-malignant diseases. This technique uses multiple radiation...Full Text Available

328

High Speed Cylindrical Roller Bearing Development.

Sensory experience plays a crucial role in regulating neuronal shape and in developing synaptic contacts during brain formation. These features are required for a neuron to receive, integrate, and transmit...Full Text Available

329

Germ cell sex determination in mammals

High speed experimental tests provided data on six parametric cylindrical roller bearings. Four bearing variables were evaluated and the results were correlated with the analytical model developed under Naval Air Propulsion Center Contract N00140-76-C-038...

1980-01-01

330

One of the major decisions that germ cells make during their development is whether to differentiate into oocytes or sperm. In mice, the germ cells’ decision to develop as male or female depends...Full Text Available

2009-04-01

331

Geothermal status report

GSFC Information Systems Technology Developments Supporting the Vision for Space Exploration.

This article examines the effects of competition of geothermal energy production with other technologies. The topics of the article include near-term market growth, cause for cautious optimism, limits to development of geothermal energy production, economic arguments for development of geothermal power plants, the effects of a competitive market on industry survival.

332

From Leningrad to the day-care center. The ubiquitous Giardia lamblia.

The Vision for Space Exploration will guide NASA's future human and robotic space activities. The broad range of human and robotic missions now being planned will require the development of new system-level capabilities enabled by emerging new technologie...

2005-01-01

333

Free and Conjugated Indole-3-Acetic Acid in Developing Bean Seeds ¹

Giardiasis is recognized as a worldwide public health problem. Seroprevalence data from both the developing and developed world show high rates of carriage in populations at risk for fecal-oral transmission,...Full Text Available

1990-08-01

334

Forschungszentrum Juelich, Institut fuer Kernphysik/COSY. Annual report 2004

The changes in conjugated indole-3-acetic acid (IAA) levels compared to the levels of free IAA have been analyzed during the development of bean (Phaseolus vulgaris L.) seed using quantitative...Full Text Available

1989-10-01

335

Final Report on the Evaluation of the NSF's Instructional Materials Development Program

The following topics are dealt with: Detectors at COSY, major physics results at COSY, physics at external facilities, theoretical investigations, COSY operation and developments, preparations for FAIR, technical developments. (HSI)

2005-03-01

336

Factors Predicting and Reducing Mortality in Patients with Invasive Staphylococcus aureus Disease in a Developing Country

... of the Evaluation of the Instructional Materials Development Program (PDF, 412 kb) Chapter I ... kb) Appendix 2: Instrument for Evaluating Materials (PDF, 935 kb) Appendix 3: Classroom Observation ...

337

Executive Development Journeys The Essence of Customized Programs

BackgroundInvasive Staphylococcus aureus infection is increasingly recognised as an important cause of serious sepsis across the developing world, with mortality...Full Text Available

338

Evaluation of tilted cone-beam CT orbits in the development of a dedicated hybrid mammotomograph

Summarizing the three main reasons why customized programs are commissioned, this book explains and explores the key aspects of successful development programs, with views from corporate sponsors, participants, faculty contributors and case studies of customised programs commissioned by 6 organizations

2010-01-01

339

Evaluation of one-pile foundations for wind turbines. Beoordeling van eenpaalsfundaties voor windturbines

A compact dedicated 3D breast SPECT-CT (mammotomography) system is currently under development. In its initial prototype, the cone-beam CT sub-system is restricted to a fixed-tilt circular rotation...Full Text Available

2009-06-21

340

Energizing the batteries for electric cars

A procedure has been developed for judging one-pile foundations for wind turbines. It appears that these foundations are good alternatives for block foundations. It is recommended to develop a program for testing one-pile foundations and to carry out a further research into their dynamic behavior.

1986-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

341

Endogenous expression of Hras^G12V induces developmental defects and neoplasms with copy number imbalances of the oncogene

This article reports of the nickel-metal-hydride battery and its ability to compete with the lead-acid battery in electric-powered vehicles. The topics of the article include development of the battery, the impetus for development in California environmental law, battery performance, packaging for the battery's hazardous materials, and the solid electrolyte battery.

1993-07-01

342

Effect of physiological levels of caffeine on Ca²⁺ handling and fatigue development in Xenopus isolated single myofibers

We developed mice with germline endogenous expression of oncogenic Hras to study effects on development and mechanisms of tumor initiation. They had high perinatal mortality, abnormal...Full Text Available

2009-05-12

343

Economic and financial issues relating to renewable energy systems in developing countires

The purpose of the present study was to determine whether exposure to exogenous physiological concentrations of caffeine influence contractility, Ca²⁺ handling, and fatigue development...Full Text Available

2009-05-01

344

EARLY FLOWERING3 Encodes a Novel Protein That Regulates Circadian Clock Function and Flowering in Arabidopsis

The problems of introducing renewable energy systems into communities having meagre resources are analysed. Topics covered include financial and economic barriers, subsidies and bank policy. It is concluded that without satisfactory financing mechanisms, renewable energies are unlikely to be widespread in the developing world. (UK)

1995-12-31

345

EARLY BILATERAL SENSORY DEPRIVATION BLOCKS THE DEVELOPMENT OF COINCIDENT DISCHARGE IN RAT BARREL CORTEX

Higher plants use photoperiodic cues to regulate many aspects of development, including the transition from vegetative to floral development. The EARLY FLOWERING3 (ELF3)...Full Text Available

2001-06-01

346

Downstream genes of Pax6 revealed by comprehensive transcriptome profiling in the developing rat hindbrain

Several theories have proposed a functional role for synchronous neuronal firing in generating the neural code of a sensory perception. Synchronous neural activity develops during a critical...Full Text Available

2009-02-25

347

Developments of heavy-ion gas detectors at LNL

BackgroundThe transcription factor Pax6 is essential for the development of the central nervous system and it exerts its multiple functions by regulating the expression of downstream...Full Text Available

348

Development of rat CA1 neurones in acute Versus organotypic slices: role of experience in synaptic morphology and activity

The most important developments in gaseous detectors at LNL are reviewed. Some aspects of timing, pulse height and position resolutions of avalanche counters are reported. The experimental work on heavy-ion identification by Bragg curve spectroscopy is summarized.

1984-05-01

349

Development of engineered structural barriers for nuclear-waste packages

Despite their wide use, the physiological relevance of organotypic slices remains controversial. Such cultures are prepared at 5 days postnatal. Although some local circuitry remains intact, they develop...Full Text Available

2003-07-01

350

Development of an Interference Electron Microscope.

The development of structural barriers for nuclear waste packages involves selection of candidate materials, their screening by mechanical and corrosion testing, rigorous accelerated testing, and evaluation and comparison with other package elements. This document presents results from work conducted on titanium and ferrous alloys.

1981-09-01

351

Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment.

This report covers a further year's work on the development of an Interference Electron Microscope at Imperial College. The instrument is unlike others of its type which have been operated. The basic innovations are to produce the critical illumination co...

1967-01-01

352

Development of a coal fired pulse combustor for residential space heating. Technical progress report, October--December 1986

A physiologically based pharmacokinetic (PBPK) model was developed that provides a comprehensive description of the kinetics of trichloroethylene (TCE) and its metabolites, trichloroethanol (TCOH),...Full Text Available

2000-05-01

353

Development of a Novel Post-processing Treatment Planning Platform for 4D Radiotherapy

This progress report presents a detailed description of the background, technology and application, and Statement of Work for the development of a coal-fired pulse combustor for residential space heating.

1986-12-31

354

Development and evaluation of a virtual microscopy application for automated assessment of Ki-67 expression in breast cancer

The aim of this study is to develop an Automatic Post-processing Tool for four-dimensional (4D) treatment planning (APT4D) that enables the user to perform some necessary procedures related...Full Text Available

2008-04-01

355

Development and Validation of the Convalescence And Recovery Evaluation (CARE) for Measuring Quality of Life after Surgery

BackgroundThe aim of the study was to develop a virtual microscopy enabled method for assessment of Ki-67 expression and to study the prognostic value of the automated analysis in...Full Text Available

356

Development and Application of Pathovar-Specific Monoclonal Antibodies That Recognize the Lipopolysaccharide O Antigen and the Type IV Fimbriae of Xanthomonas hyacinthi

PurposeTo develop a generic instrument for measuring short-term health status in the recovery period among patients undergoing abdominal and pelvic surgery.Full Text Available

2008-08-01

357

Development Document for Proposed Effluent Limitations Guidelines and Standards for the Concentrated Aquatic Animal Production Industry Point Source Category.

The objective of this study was to develop a specific immunological diagnostic assay for yellow disease in hyacinths, using monoclonal antibodies (MAbs). Mice were immunized with a crude cell wall preparation...Full Text Available

1999-09-01

358

Development Document for Proposed Effluent Limitations Guidelines and New Source Performance Standards for the Ore Mining and Dressing: Point Source Category.

This section presents background information supporting the development of effluent limitations guidelines and standards for the concentrated aquatic animal production (CAAP) point source category. Section 1.1 presents the legal authority to regulate the ...

2002-01-01

359

This document presents the findings of an extensive study of the ore mining and dressing industry, for the purpose of developing effluent limitations guidelines for existing point sources and standards for performance new sources, to implement Sections 30...

1982-01-01

360

Defect modelling

Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.

Calculations, drawing principally on developments at AERE Harwell, of the relaxation about lattice defects are reviewed with emphasis on the techniques required for such calculations. The principles of defect modelling are outlined and various programs developed for defect simulations are discussed. Particular calculations for metals, ionic crystals and oxides, are considered. (UK).

1980-03-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

361

Combining Google Earth and GIS mapping technologies in a dengue surveillance system for developing countries

Vulnerable periods during the development of the nervous system are sensitive to environmental insults because they are dependent on the temporal and regional emergence of critical developmental processes...Full Text Available

2000-06-01

362

Chagas disease: an impediment in achieving the Millennium Development Goals in Latin America

BackgroundDengue fever is a mosquito-borne illness that places significant burden on tropical developing countries with unplanned urbanization. A surveillance system using Google...Full Text Available

363

Calcitriol but no other metabolite of vitamin D is essential for normal bone growth and development in the rat.

BackgroundAchieving sustainable economic and social growth through advances in health is crucial in Latin America within the framework of the United Nations Millennium Development...Full Text Available

364

Biobank resources for future patient care: developments, principles and concepts

To determine the relative importance of different metabolites of vitamin D in bone growth and development, weanling male rat pups suckled by vitamin D-deficient mothers were given either calcitriol...Full Text Available

1984-02-01

365

Barotrauma developed during intra-hospital transfer -A case report-

The aim of the overview is to give a perspective of global biobank development is given in a view of positioning biobanking as a key resource for healthcare to identify new potential markers that can...Full Text Available

366

Astrocyte-Derived Vascular Endothelial Growth Factor Stabilizes Vessels in the Developing Retinal Vasculature

A 74-year-old male patient receiving ventilatory support due to aspiration pneumonia developed bilateral pneumothorax, pneumopericardium, pneumomediastinum, pneumo-retroperitoneum, and subcutaneous...Full Text Available

2010-12-01

367

Association of Thyroid Hormone Concentrations with Levels of Organochlorine Compounds in Cord Blood of Neonates

Vascular endothelial growth factor (VEGF) plays a critical role in normal development as well as retinal vasculature disease. During retinal vascularization, VEGF is most strongly expressed by not yet...Full Text Available

368

Angiotensin II Promotes Development of the Renal Microcirculation through AT₁ Receptors

BackgroundThyroid hormones are important regulators of brain development. During critical periods of development, even transient disorders in thyroid hormone availability may lead...Full Text Available

2007-12-01

369

Analysis of the Development of the Nasal Septum according to Age and Gender Using MRI

Pharmacologic or genetic deletion of components of the renin-angiotensin system leads to postnatal kidney injury, but the roles of these components in kidney development are unknown. To test the hypothesis...Full Text Available

2010-03-01

370

Analysis of target cell susceptibility as a basis for the development of a chemoprotective strategy against benzene-induced hematotoxicities.

ObjectivesThis study was designed to evaluate the normal development of the nasal septum in Koreans using sagittal MRI for the valuable clinical information on septal procedures.MethodsTwo...Full Text Available

2008-03-01

371

An outline of the Sunshine Project in 1982

A goal of our research is to identify biochemical factors that underlie the susceptibility of bone marrow cell populations to benzene metabolites so as to develop a mechanistically based chemoprotective...Full Text Available

1996-12-01

372

Agricultural R&D, technology and productivity

The Sunshine Project of Japan was inaugurated in 1974. Since 1980 it has been promoting priority projects such as coal liquefaction. Japan is now promoting the basic and applied research that underpins this development and is increasing the efficiency of technical development. With regard to risk dispersion, the expansion of international cooperation such as the IEA is being promoted.

1982-01-01

373

Adapting developing country epidemiological assessment techniques to improve the quality of health needs assessments in developed countries

The relationships between basic and applied agricultural R&D, developed and developing country R&D and between R&D, extension, technology and productivity growth are outlined....Full Text Available

2010-09-27

374

Acetylsalicylic acid as soluble tablets

BackgroundWe were commissioned to carry out three health assessments in urban areas of Dublin in Ireland. We required an epidemiologically robust method that could collect data rapidly...Full Text Available

375

Acetolactate Synthase Activity in Developing Maize (Zea mays L.) Kernels

Realization of Pharmacological Tests, Development of the Specifications and Technical Documentation and Registration in the Russian Federation of Medical Products as Soluble Tablets of Acetylsalicylic Acid/Calcium Carbonate in Two Dosages Intended for use as Medical Products Smoothing, Febrifugal and Antiaggregation Action and Development of Technology of Tableting the Above-Stated Preparations

376

A model of personality change after traumatic brain injury and the development of the Brain Injury Personality Scales

Acetolactate synthase (EC 4.1.3.18) activity was examined in maize (Zea mays L.) endosperm and embryos as a function of kernel development. When assayed using unpurified homogenates,...Full Text Available

1988-01-01

377

A conserved switch in sensory processing prepares developing neocortex for vision

ObjectiveThe aims of this study were to develop models of personality change after traumatic brain injury (TBI) based on information provided by the TBI survivor and a significant...Full Text Available

2007-11-01

378

A Comparison of the Metabolic Fate of Fatty Acids of Different Chain Lengths in Developing Oilseeds

Developing cortex generates endogenous activity that modulates the formation of functional units, but how this activity is altered to support mature function is poorly understood. Using recordings...Full Text Available

2010-08-12

379

45 CFR 1304.24 - Child mental health.

To determine if medium and long chain fatty acids can be appropriately metabolized by species that normally produce 16 and 18 carbon fatty acids, homogenates of developing Cuphea wrightii, Carthamus...Full Text Available

1989-07-01

380

Washington: a guide to geothermal energy development

... 2010-10-01 false Child mental health. 1304.24 Section 1304.24 Public...HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION...AGENCIES Early Childhood Development and Health Services § 1304.24 Child...

2010-10-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

381

Vacuum Packaging for Microelectromechanical Systems ...

A brief overview is given of the geological characteristics of each region of the state as they relate to potential geothermal development. Those exploration methods which can lead to the siting of a deep exploration well are described. Requirements and techniques needed for drilling deeper higher temperature exploration and production wells are presented. Electrical generation, direct utilization, and indirect utilization are reviewed. Economic factors of direct use projects are presented. A general guide to the regulatory framework affecting geothermal energy development is provided. The general steps necessary to gain access to explore, develop, distribute, and use geothermal resources are outlined. (MHR)

1980-01-01

382

Update of the Navy Contract Writing Guide

... more than expected in developing a unique bond strength measurement protocol that is important for a wide range of bond strength measurements. ...

2002-10-01

383

Untitled - NASA Technical Report Server (NTRS)

... These requirements may be expressed in terms of MIL-STD-2073-1, DoD Material Procedures for Development and Application of Packaging ...

2004-06-01

384

Tritium Oxide Content Control

Directional audio technology for headphone applications is being developed. A laboratory demonstration model of a real-time digital ...

385

Trauma Patient Followup Registry

Development of Method and Technical Project of the Plant for Thermo-Vacuum Desorption of Tritium Oxide (HTO) from the Environmental Samples

386

Thermally developing flow in curved square ducts with internal fins

... Abstract : The goal of this project has been to explore and document the information management capabilities needed to develop a transportable ...

1987-07-31

387

Theme and policy for international development of Japanese nuclear energy industries

The laminar incompressible hydrodynamically fully developed and thermally developing flow is studied in a curved square duct with four longitudinal fins. The duct is successively subjected to constant wall temperature, to circumferentially uniform temperature and axially linearly or exponentially varying temperature. The local and fully developed Nusselt numbers are examined for various values of the Dean number and it is found that the heat transfer rate increases for high fins. The parameters that affect the entry length are studied and the fluctuations of the local Nu that appear in the entrance region are investigated. Temperature contour plots are presented for the visualization of the temperature field and functional relations for the Nusselt number are proposed in terms of the Dean and Prandtl numbers. (orig.)

2005-11-01

388

The impact of core flow rate on the water chemistry and corrosion in boiling water reactors

Aug 2010 p. 31-35 Japan Kishioka, Kazuhiko Japan Atomic Industrial Forum,

2010-08-01

389

The challenge of implementing an IRP process in Asia: The case of Hainan Province, China

... Development Center, National Tsing-Hua University, Hsinchu, TW (China)

2008-05-01

390

The New Pacific Security Environment: Challenges and ...

Developing a modern electric power sector is necessary for economic growth and development to proceed. Institutions to implement an IRP (integrated resource planning) process do not exist in many countries. Hainan`s economy is growing rapidly with a concomitant increase in electricity demand. This is an ideal time in Hainan`s development to implement an IRP process. The challenge is for Hainan to develop institutions and incentive mechanisms for HEPCO (Hainan Electric Power Co.) to adopt cost-based pricing, run DSM programs, construct renewable generating plants, etc. One proposal is to great a Hainan government-wide IRP committee.

1994-12-31

391

The National Shipbuilding Research Program, 1992 Ship ...

... The Taiwanese business community is inter- ested in developing access to potential markets as well as to sources of raw materials and some ...

2011-05-13

392

The Influence of pH on the Color Development of Melanoidins Formed from Fructose/Amino Acid Enantiomer Model Systems

... Development Document for Proposed Effluent Limitations Guidelines and Standards for the Shipbuilding and Repair Point Source Category (Draft ...

1992-09-01

393

THEORY AND DESIGN CONSIDERATIONS IN DEVELOPING ...

Full Text Available

2008-12-01

394

Sunflower power system test report topical report, nov. - 19 dec. 1962

... folgen. Die notwendigen Sch~ritte -an isotherme Verh~ltnisce an den, von der Versuchssubstanz benetzten Wandungen, zu ...

1966-09-01

395

Strategic Communication and the Combatant Commander

Sunflower power conversion system development test program

1964-01-01

396

... for International Development representatives. 3. If there is SC policy guidance, use it. If not, ask for it. In many cases, summaries ...

2009-10-01

397

Steam turbines

The author gives the historical development of steam-turbine construction in Europe since the turn of the century, and the technical further development of conventional turbines due to the increases in the steam parameters and per-unit outputs in the increases in the steam parameters and per-unit outputs in Europe and the USA. Marginal conditions for the development of turbines in nuclear power stations with light-water reactors are mentioned. The rise in the per-unit capacities of the turbosets constructed in Germany and the USA for nuclear power stations is discussed. Longitudinal sections through typical turbines are shown. The future development of turbines with high output is dealt with. (orig.).

398

Steam turbines

Spectroscopy, colorimetry, and biological chemistry in the nineteenth century.

A report is given on the development and operational experience in steam turbines in an annual review. The author refers to an extensive bibliography on this subject. (TK/LH).

399

Shock and Impact Response of Naval Composite Structures

The development of colorimetry and spectroscopy in the nineteenth century is described. An account is given of the application of their techniques to biological chemistry during that period.

1981-03-01

400

Separator Plates with Metal Felt Insertions

... at the end of this report. A. Low-Velocity Impact of Composite Sandwich Panels In 2007, the PI developed analytical solutions ...

2010-08-09

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

401

Self-Propagating High-Temperature Synthesis Technologies

Development of Bipolar Separator Plates with Porous Insertions of Metal Felt as Bearing Surfaces for Fuel Cell Electrodes

402

SAMS Research and Development

Development of SHS-technologies for SiC, Si3N4 and Ceramic Composites on Their Basis from Rocks

403

Release 01-93 - NASA Human Space Flight

... resolution video. RESULTS Statistics describing the typical inertial navigation error growth were collected. Typical errors ...

2008-08-06

404

RXTE Catches Morphing Magnetar

These cutting-edge developments will be used for future government and commercial launch systems and space transportation operations. ...

405

R&D prioritization and resource management for technology selection

This exciting new development in neutron star evolution was presented at the Winter 2004 AAS Meeting in Atlantia,Georgia. ...

406

This paper presents a decision approach, and associated computer software tools, for prioritizing and selecting among technology development activities. The approach elicits and then summarizes technology development preferences from stakeholders, and then integrates preferences into a set of funding recommendations. By formalizing the technology review process, the decision approach builds consensus and clarifies the basis for final budget decisions. The software development was conducted jointly by Pacific Northwest Laboratory and Decisions Science Associates, Incorporated. The Underground Storage Tank Integrated Demonstration funded the task; however, the approach should also be valuable to the US Department of Energy Office of Technology Development, the Office of Waste Management, and the Office of Environmental Restoration.

1994-03-01

407

PowerPoint Presentation

Performance Testing Methodology for Safety-Critical Programmable Logic Controller

facilities, building hygienic latrines and introducing regular solid waste collection systems . These methods are constantly being developed and

408

Overview of US LMFBR Structural Materials Mechanical Properties Program

The Programmable Logic Controller (PLC) for use in Nuclear Power Plant safety-related applications is being developed and tested first time in Korea. This safety-related PLC is being developed with requirements of regulatory guideline and industry standards for safety system. To test that the quality of the developed PLC is sufficient to be used in safety critical system, document review and various product testings were performed over the development documents for S/W, H/W, and V/V. This paper provides the performance testing methodology and its effectiveness for PLC platform conducted by KOPEC

2009-05-01

409

Overview of U.S. LMFBR structural materials mechanical properties program

This paper presents the objective, scope, and status of the US Department of Energy's Materials and Structures Program to develop a data base on mechanical properties of structural materials for out-of-core structures and components for LMFBRs. Information on the development of a reference data base on materials for the reactor system, reactor enclosure system, primary heat transport system, intermediate heat transport system, and steam generator system is included. In addition, the development of the data and analyses to account for the effects of temperature and stress, as well as water/steam, sodium, and radiation environments, is described. Plans for the development of alternative materials for future out-of-core applications are presented.

1983-01-01

410

New developments in the surveillance and diagnostics technology for vibration, structure-borne sound and leakage monitoring systems

This paper presents the objective, scope, and status of the U.S. Department of Energy's Materials and Structures Program to develop a data base on mechanical properties of structural materials for out-of-core structures and components for LMFBRs. Information on the development of a reference data base on materials for the reactor system, reactor enclosure system, primary heat transport system, intermediate heat transport system, and steam generator system is included. In addition, the development of the data and analyses to account for the effects of temperature and stress, as well as water/steam, sodium, and radiation environments, is described. Plans for the development of alternative materials for future out-of-core applications are presented. (author).

1983-10-10

411

Monitoring and diagnostic systems are of main importance for a safe and efficient operation of nuclear power plants. The author describes new developments with respect to vibration monitoring with a functional extension in the time domain for den secondary circuit, the development of a local system for the surveillance of rotating machines, the structure-borne sound monitoring with improvement of event analysis, esp. the loose part locating, leakage monitoring with a complete system for humidity measurement, and the development of a common platform for all monitoring and diagnostic systems, that allows an efficient access for comparison and cross references.

412

NRL Fact Book 2010

... Tactical Electronic Warfare Division (Code 5700) Visualization Laboratory Transportable step frequency radar Vehicle development laboratory ...

2011-05-15

413

NRL Fact Book

NASA/BAE SYSTEMS SpaceWire Effort

... Tactical Electronic Warfare Division (Code 5700) Visualization Laboratory Transportable step frequency radar Vehicle development laboratory ...

2011-05-15

414

More iPhone Cool Projects

This paper discusses the state of the NASA and BAE SYSTEMS developments of SpaceWire. NASA has

2003-01-01

415

Magnetic resonance imaging in childhood epilepsy

Everyone is developing iPhone applications, and it's clear why. The iPhone is the coolest mobile device available, and the App Store makes it simple to get an application out into the unstoppable iPhone app market. With hundreds of thousands of app developers entering the game, it's crucial to learn from those who have actually succeeded. This book shows you how some of the most innovative and creative iPhone application developers have developed cool, best-selling apps. Not only does every successful application have a story, but behind every great app is excellent code. In this book, you'll

2010-01-01

416

Lunar Communication & Navigation Architecture

The suitability of MR imaging versus computerized tomography in observation of brain development disorders in children are compared. 13 refs.

417

Prior to this at TRW, Mr. Schier managed flight software development on the MILSTAR Communications Payload and led integration and verification work on ...

418

Low-Cost Crystal Silicon

Liquid nitrogen dewar for protein crystal growth

The Development of Basic Plasma-Chemical Technology for Manufacture of Low Cost Crystal Silicon for Solar Power Plants.

419

Keratoconus: Frequently Asked Questions

Gaseous Nitrogen Dewar apparatus developed by Dr. Alex McPherson of the University of California,

2001-01-01

420

JPRS Report, Nuclear Developments

... a new cornea? As many of you know stem cell research and efforts to develop a replacement cornea have ...

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

421

Investigating Models of Social Development Using a ...

... II. Nuclear Purification Nuclear purity is achieved with the help of the treatment of commercial concentrates of uranium ("yellow cake"). ...

1988-06-03

422

India's tryst with modern astronomy

... taker', Adaptive Behavior. In submission. Behavioral Disorders: Diagnostic Criteria for Re- Breazeal (Ferrell), C. (1998), A Motivational System for ...

2011-05-13

423

Improved Usability of Locomotion Devices Using Human ...

Sumedh Anathpindika surveys astronomy in India and finds a lively and developing community as well as great public interest.

2011-01-01

424

Imaging Automation and Volume Tomographic Visualization at Texas Neutron Imaging Facility

... increasing photorealism. Furthermore, developments in audio technology continue to increase the spatial awareness of users in VEs. ...

2009-03-01

425

IT development and application practices in Daya Bay Nuclear Power Station

A thermal neutron imaging facility for real-time neutron radiography and computed tomography has been developed at the University of Texas reactor. The facility produced good-quality radiographs and two-dimensional tomograms. Further developments have been recently accomplished. A computer software has been developed to automate and expedite the data acquisition and reconstruction processes. Volume tomographic visualization using Interactive Data Language (IDL) software has been demonstrated and will be further developed. Volume tomography provides the additional flexibility of producing slices of the object using software and thus avoids redoing the measurements.

1999-11-14

426

Human Systems Center Products and Progress.

2002 p. 139 China Sun Haiying Ye Zhiqiang Bu Jianhua Guangdong Nuclear

427

How the Energy and Water Development Appropriations Act of 1993 has impacted the constitutional dynamics of federal wetlands delineation and regulation

... Page 43. Integrated Audio Technology Demonstrator The Integrated Audio Technology Dem- development for this application is successful. ...

1993-10-01

428

HARPHRQ. A Geochemical Speciation Program Based on PHREEQE

A reliable source of specific criteria for recognizing a wetland, as defined for regulatory purposes would be valuable. In 1987 the Army Corps of Engineers developed a technical manual for identifying wetlands (1987 Wetlands Manual). An interagency manual (1989 Wetlands Manual) was later developed. This manual has been used to identify wetlands according to three evidentiary factors: vegetation, hydrology, and soil. This paper addresses the development of criteria to delineate wetlands, and describes some of the logic used by federal courts to uphold the limited constitutional use of the 1989 Wetlands Manual.

1995-12-31

429

Growth, Characterization and Device Development in ...

HARPHRQ is a geochemical speciation program developed at Harwell and based on the U.S. Geological Survey code Phreeqe.

1992-02-18

430

Geometric and topological methods for quantum field theory

... eV. In some instances the spontaneous radiation from a free electron laser system was employed to obtain images. The ...

1998-03-01

431

Fungal laccases: production, function, and applications in food processing.

An introduction to recent developments in several active topics at the interface between algebra, geometry, topology and quantum field theory

2010-01-01

432

Fibrillation of Commercial Acrylic Fiber for Use in Combustible Cartridge Cases.

Laccases are increasingly being used in food industry for production of cost-effective and healthy foods. To sustain this trend widespread availability of laccase and efficient production systems have to be developed. The present paper delineate the recent developments that have taken place in understanding the role of laccase action, efforts in overexpression of laccase in heterologous systems, and various cultivation techniques that have been developed to efficiently produce laccase at the industrial scale. The role of laccase in different food industries, particularly the recent developments in laccase application for food processing, is discussed. PMID:21048859

2010-09-21

433

FURTHER DEVELOPMENT OF THE AN/DMQ-9 ...

A production method was developed to fibrillate commercial acrylic fiber suitable for the manufacture of combustible cartridge cases.

1983-01-01

434

Energy Engineering Analysis Program (EEAP), Cornhusker ...

... is disengaged from the spent rocket motor by a ... of the outbound and incoming modu- ... meteorological sensor and reference resistor is accomplished ...

1965-06-01

435

Enabling Lightwave Electronics with Nanotechnology ...

... is to develop a systematic program of energy consumption reductions in compliance with the stated goals of the Army Facilities Energy Plan (AFEP ...

1984-03-01

436

Effect of low dose of radioactive iodine on mammalian brain development

... Acousto-optic programmable dispersive filters (AOPDF) have been developed for optical signal processing, polarization switching in lasers, and ...

2011-03-29

437

E-13662-1 Layout - GLTRS - NASA

Russian 1997 p. 266-267 Russian Federation Ushakova, GA

438

Discussion on closed nuclear fuel cycle strategy in China

Group for Aerospace Research and Development (AGARD) symposium and continue to ...... of vertical structures and flow separation within the tip, platform, ...

439

Development of the EE-1 small community solar thermal power system

According to China's 'Medium- and Long-term Nuclear Power Development Program (2005-2020)', nuclear energy development in China will take the technical line of closed nuclear fuel cycle. This paper discusses the significance of closed nuclear fuel cycle, and briefly introduces development trends in the world. This article also discusses the opportunity to construct spent fuel reprocessing plant; equilibrium of plutonium production and consumption; adaptability and economics to use MOX fuel in the thermal neutron reactor. Some suggestions are put forward to the overall development of nuclear energy in China. (authors)

2008-05-01

440

Development of equipment for irradiated nuclear fuel reprocessing plant

The development status of the EE-1 Small Community Solar Thermal Power Experiment (SCSE Program) is presented. Current activities on the Phase II single module development effort are presented, together with plans for a Phase III 1 MW/sub e/ demonstration plant. A description of the various subsystems and components is given with a brief review of their development background. Latest performance figures are given for a 1 MW/sub e/ plant, based on 56 power modules, each consisting of a 12m parabolic dish concentrator, a cavity receiver, an organic Rankine power conversion subsystem and a ground-mounted solid-state rectifier.

1981-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

441

Development of an efficient, low-NOx domestic gas range cooktop. Phase 3. Final report, January 1986-December 1988. Technical report

2002 p. 9-10, 83-84 Russian Federation Glagolenko, Yu.V. Dzekun, EG

442

Development of an Agroforestry Sequestration Project in Khammam District of India | International Energy Studies

The objective of the program was to develop a domestic cooktop with low-NOx emissions and high efficiency. During the first two phases of the program, three design concepts were developed, and two versions of developmental prototypes using the IR-Jet approach were fabricated and tested. The third phase was initiated to address the design issues of a simmer setting, air/gas metering, and jet plate durability and to develop prototypes for interested manufacturers.

1989-10-01

443

Development of a solvent extraction process for cesium removal from SRS tank waste

...Development of an Agroforestry Sequestration Project in Khammam District of India | International Energy Studies International Energy Studies News | Researchers | Publications ...Technologies Division Industrial Innovations Industrial Energy Analysis Copyright &1692006 Disclaimer Development of an Agroforestry Sequestration Project in Khammam District of India Authors:P. Sudha; V.... Vasistha 2006-10-10 0 Development of an Agroforestry Sequestration Project in Khammam District of India P. Sudha, V. Ramprasad, M.D.V. Nagendra,...

444

Development of a CFD Program for Cold Gas Flow Analysis in a High Voltage Circuit Breaker Using CFD-CAD Integration

An alkaline-side solvent extraction process was developed for cesium removal from Savannah River Site (SRS) tank waste. The process was invented at Oak Ridge National Laboratory and developed and tested at Argonne National Laboratory using singlestage and multistage tests in a laboratory-scale centrifugal contactor. The dispersion number, hydraulic performance, stage efficiency, and general operability of the process flowsheet were determined. Based on these tests, further solvent development work was done. The final solvent formulation appears to be an excellent candidate for removing cesium from SRS tank waste.

2001-06-30

445

Development of Jelly-Type Simulating Polymer Based Human Tissue for Research on Hyperthermia by High Frequency Magnetic Field

Full Text Available

2002-05-01

446

Development of Decision Making Model for Optimal Location of Washland based on Flood Control Effect estimated by Hydrologic Approach

Full Text Available

2006-11-01

447

Development and Calibration of Two and Four Wire Water ...

Full Text Available

2008-07-01

448

Development Document for Proposed Effluent Limitations Guidelines, New Source Performance Standards, and Pretreatment Standards for the Iron and Steel Manufacturing Point Source Category.

... measurement. Power spectral density measurements are made by the dynamic signal analyzer for each channel. A cross power ...

1992-12-01

449

Development Document for Proposed Effluent Limitations Guidelines and New Source Performance Standards for the Organic Chemicals and Plastics and Synthetic Fibers Industry.

No abstract available.

1980-01-01

450

No abstract available.

1983-01-01

451

Development - NASA

Design, Fabrication, Test, and Evaluation of Spiral Bevel ...

12], the Predictive Capability Maturity Model (PCMM) [ref. 13], the Uncertainty Structure scale [ref. 11], and the Simulation Readiness Level (SRL) scale ...

452

DEVELOPMENT OF KSC PROGRAM FOR INVESTIGATING AND - NASA Technical ...

... Development Tapered Roller Bearing Program . . . 11 ... 98 61 Tapered Roller Bearing Component t Identification..... 104 ...

1973-06-01

453

DEVELOPMENT OF A TUNED DAMPER TO REDUCE ...

Aluminum electrolytic capacitors, with 1043 failures, are a good example. Also, categorization by size and voltage reveals such frequencies of occurrence as ...

454

Considerations in the Design and Development of a Human ...

... Since power spectral density measurements are the result of a statisti- cal sampling process, as are the probability measurements, we now ...

1967-09-01

455

Concerning a Comprehensive Nuclear Test Ban

... appropriate. At press time, the laws governing the use of digital audio technology and the technology itself are rapidly changing. ...

1990-09-20

456

Combustible Cartridge Cases, an Account of the Current ...

... US Congress, Joint Committee on Atomic Energy, Development, Use, and Control ofNuclear Energy for the Common Defense and Security and for ...

2011-05-14

457

Chiral dynamics of few-nucleon systems

... ADA185428. Title : Combustible Cartridge Cases, an Account of the Current Technology and Proposals for Future Development. ...

1986-10-01

458

Carbon Smackdown: Cookstoves for the developing world

I discuss some recent developments in chiral effective field theory for few-nucleon systems.

2008-06-01

459

ScienceCinema

...contribution to global warming ...states i think impact of global warming ? and ...contributor to global warming ...

460

COMMUNICATION MEDIA AND EDUCATIONAL TECHNOLOGY AN - NASA Technical ...

COMBUSTIBLE AMMUNITION FOR SMALL ARMS. 1. ...

adaptations of analog audio technology Recent developments in tape cassette technolocy have made Itpossible to provide up to ...

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

461

Asperger Syndrome - What it Feels Like (3)

... Research on development of combustible cartridge cases for small arms was conducted in Germany during World War II. ...

1960-05-01

462

Brain Basics

Medline Plus

... Such disorders include depression , anxiety disorders , bipolar disorder , attention deficit hyperactivity disorder (ADHD) , and many others. Some people who develop ...

463

Applied nuclear science research and development. Semiannual progress report, October 1, 1983-May 31, 1984

Jake, who has been diagnosed with Asperger syndrome, explains that he has developed a number of ritualistic habits.

2009-04-14

464

Anticipatory nausea and vomiting

Separate entries are individually indexed.

1985-01-01

465

British Library Electronic Table of Contents (United Kingdom)

A commonly reported consequence of post-treatment nausea or vomiting is the development of anticipatory nausea and vomiting (ANV). In most published work, nausea is reported to occur before chemotherapy drugs are administered by approximately 20% of patients at any one chemotherapy cycle and by 25?30% of patients by their fourth chemotherapy cycle. Most studies in adult patients strongly support the view that the development of ANV involves elements of classical conditioning. The best method to avoid development of ANV is to adequately prevent both vomiting and nausea from the first exposure to chemotherapy. If anticipatory side effects develop, behavioral treatment techniques, such as systematic desensitization, have been shown effective. Benzodiazepines used in combination with behaviora...

2011-01-01

466

An object oriented software bus

An application of possibilistic programming to the fuzzy location?allocation problems

This paper describes a new approach to development of software for highly integrated software-hardware systems such as used for data acquisition and control. This approach, called the Object Oriented Software Bus (OSB), is a way to develop software according to a common specification similar to the way interface hardware has been developed since the advent of bus structures for minicomputers and microcomputers. Key concept of the OSB is extension of the common use of objects to support user interface and data analysis functions to the development of software objects that directly correspond to real- world hardware interfaces and modules.

1995-12-31

467

British Library Electronic Table of Contents (United Kingdom)

This paper considers location?allocation problem in the real uncertain world and develops a possibilistic non-linear programming model to deal with this problem. Fuzzy decision making in fuzzy environment concept is used to determine possibility distribution of location and allocation variables. To solve this model, a novel approach based on genetic algorithm structure is developed. As the proposed model includes both deterministic (location) and uncertain (allocation) parameters, the developed solution algorithm uses a hybrid chromosome structure. Also, to cover continuous nature of the problem and prevent GA from early convergence, a new crossover operator is introduced. Finally, performance of the developed algorithm is evaluated by an example.

2011-01-01

468

Alaska: a guide to geothermal energy development

Advanced Thermal Management for Military Application

A brief overview is given of the geological characteristics of each region of the state as they relate to potential geothermal development. Those exploration methods which can lead to the siting of a deep exploration well are described. Requirements and techniques needed for drilling deeper higher temperature exploration and production wells are presented. Electrical generation, direct utilization, and indirect utilization are reviewed. Economic factors of direct use projects are presented. A general guide to the regulatory framework affecting geothermal energy development is provided. The general steps necessary to gain access to explore, develop, distribute, and use geothermal resources are outlined. (MHR)

1980-06-01

469

Absorption-Electrochemical Surface Decontamination

... management. 5.3 Decreased Emissions Changes in engine emission regulations are driving engine technology development. A ...

2004-12-01

470

A study to develop the domestic functional requirements of the specific safety systems of CANDU

Development of a Comprehensive Decontamination Database and an Absorption-Electrochemical Metal Surface Decontamination Technique Combining Chemical and Electrochemical Process

471

A study to develop the domestic functional requirements of the specific safety systems of CANDU

The present research has been made to develop and review critically the functional requirements of the specific safety systems of CANDU such as SDS-1, SDS2, ECCS, and containment. Based on R documents for this, a systematic study was made to develop the domestic regulation statements. Also, the conventional laws are carefully reviewed to see the compatibility to CANDU. Also, the safety assessment method for CANDU was studied by reviewing C documents and recommendation of IAEA. Through the present works, the vague policy in the CANDU safety regulation is cleaning up in a systematic form and a new frame to measure the objective risk of nuclear power plants was developed.

2003-03-15

472

A Structural Approach to the Photonic Processor

The present research has been made to develop and review critically the functional requirements of the specific safety systems of CANDU such as SOS-1, SOS-2, ECCS and containment. Based on R documents for this, a systematic study was made to develop the domestic regulation statements. Also, the conventional laws are carefully reviewed to see the compatibility to CANDU. Also, the safety assessment method for CANDU was studied by reviewing C documents and recommendation of IAEA. Through the present works, the vague policy in the CANDU safety regulation is cleaning up in a systematic form and a new frame to measure the objective risk of nuclear power plants was developed.

2001-03-15

473

... UUV Unmanned Underwater Vehicle ... 26- VISION-ASSISTED ROBOT TASKS ... Specifically, the development of autonomous robots depends on ...

2011-05-14

474

27 - NASA

The results of investigations in connection with development of methods for integrated optimization of fast reactors parameters

02.10.10 - NASA and Texas Instruments are using the theme of human space exploration to develop digital libraries of math and science problems for high ...

475

Synfuels: how much can they help. [Chevron activities

The results for development of methods and computer programs for integrated optimization of parameters of perspective fast reactors are given. The possibilities of the program for the reactor campaign calculation are analysed. This program is based on utilisation of the Bubnov-Galerkin method and Wigner disturbance theory. The possibility of application of approximation methods for the optimization researches is discussed. The results of development of the programs for complex reactor computations with account of control rods system and change of physical parameters in the reactor campaign are discussed. (author).

1974-07-01

476

Progress posted in coal liquefaction technology

A series of questions and answers addresses issues related to developing synthetic fuels, including the potential supplies, regulatory road blocks, and development incentives to promote the role of the private sector. Chevron's efforts in the area of synfuels are aimed at shale oil tar sands and coal conversion. The status of these research and development projects and the projected recoverable reserves from each are summarized. (DCK)

477

Producing Open Source Software How to Run a Successful Free Software Project

This article discusses the latest developments made in the field of technology used for coal liquefaction. Some new areas of development in research and development work are described. Particular consideration is given to low-severity processing. This has two advantages, mostly low-molecular-weight fragments are produced and the extracts are low in heteroatoms. A detailed description of low-severity processing is given. The refining of the liquids produced from coal is also covered.

1986-04-28

478

Perspectives on energy storage wheels for space station application

This comprehensive guide offers several tried and true steps to help you successfully manage the complex process of developing free software. Topics include project management, developer motivation, technical infrastructure to support collaboration, and project promotion. Producing Open Source Software is ideal for developers starting their own free software projects, or people who simply want to participate in the process.

2009-01-01

479

Mitigating socio-economic impacts of energy development

Several of the issues of the workshop are addressed from the perspective of a potential Space Station developer and energy wheel user. Systems considerations are emphasized rather than component technology. The potential of energy storage wheel (ESW) concept is discussed. The current status of the technology base is described. Justification for advanced technology development is also discussed. The study concludes that energy storage in wheels is an attractive concept for immediate technology development and future Space Station application.

1984-11-01

480

IDEAS: Journal of International Trade & Economic Development, Taylor and Francis Journals

This study provides information on energy resource development and the efforts of State and local communities in the Rocky Mountain, Appalachian, and coastal regions to deal with the related social and economic impacts. It also provides information on the range of options and resources generally available to States and local communities from local, State, industry, and Federal sources to plan for and mitigate the adverse effects of energy development. Onsite visits and interviews with State, local, and Federal officials and private industry involved in mitigating socioeconomic impacts were made.

1982-03-02

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

481

Guidebook to financing CDM projects

... (restricted)] 101-127 On the transmission of exchange rate fluctuations to the macroeconomy: Contrasting evidence for developing and developed countries by Magda Kandil [Downloadable! (restricted)] 2005, Volume 14, Issue 4 377-405 Predicting the poverty impacts of trade reform by Thomas Hertel & Jeffrey Reimer [Downloadable! (restricted)] 407-435 Sustaining imperfectly credible trade liberalization: Do the rate of tariff reduction ...

482

Final report - Sundyne Company

One of the challenges facing Clean Development Mechanism (CDM) projects today is their limited ability to secure financing for the underlying greenhouse gas emission reduction activities, particularly in the least developed countries. Among the key reasons for this is the fact that most financial intermediaries in the CDM host countries have limited or no knowledge of the CDM Modalities and Procedures. Moreover, approaches, tools and skills for CDM project appraisal are lacking or are asymmetrical to the skills in comparable institutions in developed countries. Consequently, developing country financial institutions are unable to properly evaluate the risks and rewards associated with investing or lending to developers undertaking CDM projects, and therefore have, by-and-large, refrained from financing these projects. In addition, some potential project proponents lack experience in ...

2007-07-01

483

Experience from the development of Point Lepreau's training program for technical support staff

Solar cookers offer a viable alternative to conventional cooking methods in many areas, and can be an effective tool in the fight against the deforestation and desertification that plague many developing countries. However, there have been numerous obstacles to the successful dissemination of solar cookers in the past. The purpose of this paper is to identify opportunities, review constraints and develop a marketing strategy to disseminate the Sundyne Solar Cooker (SSC) in developing countries.

1994-09-27

484

Evaluation of the SYNTHOIL process. Volume II. Status of development. [47 refs

The Training Department at the Point Lepreau GS has been developing and improving its training for technical support staff. A generic set of objectives are being used as the basis for a systematic approach to training. The program covers general and job specific knowledge and skills using a mix of classroom instruction, mentoring and continuing training seminars. This paper describes experience, success and the challenges in the development, delivery and evaluation of the training program. (author)

2007-06-03

485

Energy for Lebanon of tomorrow: paradigm of sustainable development and environment

The Synthoil process for producing heavy desulfurized fuel oil from coal has been under development at Pittsburgh Energy Research Center since 1969. The status of development and technical feasibility of the process are reviewed. This is part of an engineering and economic evaluation based on the conceptual design of a 100,000-bbl/day commercial Synthoil facility. Experimental data are discussed with regard to their adequacy for the formulation of a basis for the process design of such a facility. Potential engineering and equipment problems are analyzed.

1977-06-01

486

Effect of lifetime nutrition on ruminant carcass and meat quality

An overview of the present status of energy sector in Lebanon and requirements of its future development is presented. The study is based on an economic analysis of needs and energy consumption among the population and on a comparison with other developing countries. Tables and graphs on energy distribution, needs and demands per habitant and national income are included. 3 figs. 3 tabs.

487

Environmental Research Database

DescriptionThis application is a request for Bridge Link funds to support studies in order to develop a full proposal under the Link Sustainable Livestock Scheme in collaboration with Dr Nigel Scollan of IGER. The hypothesis being examined is that the poor performance of some ruminants is due to poor nutrition at strategic time points during the animal's development. The initial hypothesis will be tested in sheep and the results from this will be used to develop the full proposal. Excessive fat in ruminan [continued...

2006-01-31

488

Effect of hydrogen on structure and properties of #beta#-titanium alloy VT-15 during bending tests in various media

Dounreay: an alternative development

It is shown that bending tests on microsamples can be used to study the conditions in which hydrogen brittleness develops. In such tests hydrogen brittleness develops in the VTI5 alloy within the temperature range +5 to -20"0C. The tendency of VTI5 to develop hydrogen brittleness is enhanced with bending in salt water. (author).

489

Development of neutral-beam injectors. Report on the third workshop, Gatlinburg, Tennessee, United States of America 19-23 October 1981

With the Government decision to phase out the Fast Reactor at Dounreay there is a need to find alternative employment in the area. Traditionally Caithness is an area of farming, fishing and tourism which could be damaged if Dounreay were to be made a nuclear waste repository. The suggestion is that Dounreay should become a centre for research, development and subsequent manufacture of renewable energy sources and devices to harness renewable energy. The Scottish coastline has potential for wind and wave power developments and this could lead to a whole industry in the future. (UK).

1991-01-01

490

Development of internal dose estimation software on radiation protection

This paper reports on the third workshop on the development of neutral-beam injectors held from 19-23 October 1981 at Gatlinburg, Tennessee, USA. The programme of the workshop was devoted to the development of positive-ion-based neutral injectors, although several techniques for producing negative ion beams were also discussed.

1982-03-01

491

Development of a high-output dual-fuel engine

Objective: To develop a computerized method of internal dose estimation on radiation protection. Methods: Based on MIRD mathematic model of the organs and by means of the programming language of MS Visual Basic 6.0, a computer program of dose estimation in internal radiation was developed for radiation protection. Results: The computerized method of dose estimation for internal radiation was completed. Conclusions: This computerized method is very convenient for internal radiation dose estimation of several aspects. It can also be used in radiation accident. (authors)

2008-10-01

492

Development and application of a gamma scanning system for LLW and MLW packages

This paper presents the results of a new dual-fuel engine development program. The engine is the largest commercially available in terms of power output (650 hp/cyl) and features very low emissions (1 g/hp-hr NO[sub x]) and excellent fuel consumption (43 percent thermal efficiency). A two-cylinder turbocharged prototype was designed and built for the initial development. Results from testing on 18-cylinder production versions are also reported.

1993-10-01

493

DEVELOPMENT AND PILOT PLANT EVALUATION OF SILICA-ENHANCED LIME SORBENTS FOR DRY FLUE GAS DESULFURIZATION (JOURNAL VERSION)

The report describes the studies carried out to design a non-destructive system for the radiological characterization of packages containing LLW and MLW. This technique is applied for quantitative and qualitative gamma emitters determination in packages with homogeneous and heterogeneous matrices as well as the development of a maximum activity points location system. Development involves also the automatization for its industrial use.

1993-09-05

494

Coal liquefaction process streams characterization and evaluation

The paper discusses recent work on lime enhancement and testing at the bench-scale, followed by evaluation of the more promising sorbents in a pilot plant to develop low cost, retrofittable flue gas cleaning technology specifically the development of highly reactive sorbents. Con...

495

Coal liquefaction process streams characterization and evaluation

Consol R D is conducting a three-year program to characterize process and product streams from direct coal liquefaction process development projects. The program objectives are two-fold: (1) to obtain and provide appropriate samples of coal liquids for the evaluation of analytical methodology, and (2) to support ongoing DOE-sponsored coal liquefaction process development efforts. The two broad objectives have considerable overlap and together serve to provide a bridge between process development and analytical chemistry.

1991-11-01

496

Coal demonstration plants. Quarterly report, October--December 1976

Consol R D is conducting a three-year program to characterize process and product streams from direct coal liquefaction process development projects. The program objectives are two-field: (1) to obtain and provide appropriate samples of coal liquids for the evaluation of analytical methodology, and (2) to support ongoing DOE-sponsored coal liquefaction process development efforts. The two broad objectives have considerable overlap and together serve to provide a bridge between process development and analytical chemistry.

1991-11-01

497

Coal demonstration plants. Quarterly report, July--September 1976

In addition to an executive summary and glossary, the following sections are included: Clean Boiler Fuel Demonstration Plant; Development of Coal Feeders for Coal Gasification Operations; Development of a Continuous Dry Coal Screw Feeder; Coal Feeder Development Program; Engineering and Technical Support; Technical Assistance Services; and Conceptual Design for an Advanced Coal Liquefaction Commercial Plant. (EJH)

1976-01-01

498

Boron in nuclear medicine: New synthetic approaches to PET and SPECT. Final report, May 1, 1986--April 30, 1996

In addition to an executive summary and glossary, the following sections are included: Clean Boiler Fuel Demonstration Plant; Development of Coal Feeders for Coal Gasification Operations; Development of a Continuous Dry Coal Screw Feeder; Coal Feeder Development Program; Engineering and Technical Support; and Technical Assistance Services. (EJH)

1976-01-01

499

Research is described in the development of organometallic reagents in which the boron was attached to a nonreactive organic or inorganic matrix such as polystyrene, silica, or alumina. We developed the synthesis of oxygen-15 labelled butanol, which has been found to be a valuable blood flow agent in humans. We have also developed a series of polymeric borane derivatives which were used to prepare nitrogen-13 labelled amines.

1997-08-01

500

Annual report 1995