WorldWideScience
1

Acute Kidney Injury in Critically Ill Patients Infected With 2009 Pandemic Influenza A(H1N1): Report From a Canadian Province  

British Library Electronic Table of Contents (United Kingdom)

Background 2009 pandemic influenza A(H1N1) has led to a global increase in severe respiratory illness. Little is known about kidney outcomes and dialytic requirements in critically ill patients infected with pandemic H1N1. Study Design Prospective observational study. Setting & Participants 50 patients with pandemic H1N1 admitted to any of 7 intensive care units in Manitoba, Canada, were prospectively followed. Outcome & Measurements Outcomes were kidney injury and kidney failure defined using RIFLE (risk, injury, failure, loss, end-stage disease) criteria or need for dialysis therapy. Results The pandemic H1N1 group was ...

2010-01-01

2

A Hypothesis: Supplementation with Mushroom-Derived Active Compound Modulates Immunity and Increases Survival in Response to Influenza Virus (H1N1) Infection.  

Science.gov (United States)

We hypothesize that the mushroom-derived active compound may be a potential strategy for increasing survival in response to influenza virus (H1N1) infection through the stimulation of host innate immune response. The validity of the hypothesis can be tested by immune response to influenza infection as seen through survival percentage, virus clearance, weight loss, natural killer cell cytotoxicity, Tumor Necrosis Factor-? (TNF-?) and Interferon-gamma (IFN-?) levels, lytic efficiency in the spleens of mice and inducible nitric oxide synthase mRNA expressions in RAW 264.7 murine macrophage cells. The hypothesis may improve people's quality of life, reduce the medical cost of our healthcare system and eliminate people's fears of influenza outbreak. PMID:21660092

2011-03-20

3

The clustering and transmission dynamics of pandemic influenza A (H1N1) 2009 cases in Hong Kong  

British Library Electronic Table of Contents (United Kingdom)

Objectives: Human influenza A (H1N1) 2009 has caused severe epidemics in many countries, but its dynamics in spatial and temporal contexts have so far been poorly appreciated. Methods: A total of 24,414 laboratory confirmed human influenza A (H1N1) 2009 cases reported from May to September 2009 in Hong Kong were evaluated, using a Geographic Information System (GIS)-based approach. Spatio-temporal clustering was assessed after dividing Hong Kong into 4 geographic sectors, 18 districts and 500 m x 500 m cells. Global Moran's I, Local Moran's I and SaTScan(TM) were used in the exploration. Results: Spatio-temporal clusters first appeared on Hong Kong Island at week 3, alongside multiple foci suggestive of infection nidus introduced from abroad. The clusters grew rapidly and became confluent ...

2011-01-01

4

Characteristic findings of pediatric inpatients with pandemic (H1N1) 2009 virus infection among severe and nonsevere illnesses  

British Library Electronic Table of Contents (United Kingdom)

We analyzed the clinical features of inpatients at a Japanese pediatric department who were infected with pandemic (H1N1) 2009 virus. Study participants included 46 children hospitalized from July 2009 to January 2010. Infection with the virus was confirmed using real-time reverse transcriptase polymerase chain reaction (RT-PCR). The epidemic month was October 2009; 34 patients were boys, and median age was 7?years. Pandemic influenza-associated respiratory diseases included pneumonia (n?=?42), bronchitis (n?=?3), and pharyngitis (n?=?1). The median time from onset to admission was 3?days. Children were divided into those with severe (n?=?32) versus nonsevere illnesses (n?=?14) according to Japanese guidelines. Significant features in the severe group were younger age, previous asthmatic a...

2011-01-01

5

Histopathological and immunohistochemical findings of 20 autopsy cases with 2009 H1N1 virus infection.  

Science.gov (United States)

Twenty autopsy cases with 2009 pandemic influenza A (2009 H1N1) virus infection, performed between August 2009 and February 2010, were histopathologically analyzed. Hematoxylin-eosin staining, immunohistochemistry for type A influenza nucleoprotein antigen, and real-time reverse transcription-PCR assay for viral RNA were performed on formalin-fixed and paraffin-embedded specimens. In addition, the D222G amino acid substitution in influenza virus hemagglutinin, which binds to specific cell receptors, was analyzed in formalin-fixed and paraffin-embedded trachea and lung sections by direct sequencing of PCR-amplified products. There were several histopathological patterns in the lung according to the most remarkable findings in each case: acute diffuse alveolar damage (DAD) with a hyaline membrane (four cases), organized DAD (one case), acute massive intra-alveolar edema with variable ...

2011-08-26

6

Flucytosine for treatment of Candida albicans in H1N1-positive patient  

UK PubMed Central (United Kingdom)

A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida...Full Text Available

2010-10-01

7

Risk Factors and Immunity in a Nationally Representative Population following the 2009 Influenza A(H1N1) Pandemic  

UK PubMed Central (United Kingdom)

BackgroundUnderstanding immunity, incidence and risk factors of the 2009 influenza A(H1N1) pandemic (2009 H1N1) through a national seroprevalence study is necessary for informing...Full Text Available

8

Replication, Pathogenesis and Transmission of Pandemic (H1N1) 2009 Virus in Non-Immune Pigs  

UK PubMed Central (United Kingdom)

The declaration of the human influenza A pandemic (H1N1) 2009 (H1N1/09) raised important questions, including origin and host range [1],...Full Text Available

9

Defense.gov News Article: DARPA Effort Speeds Biothreat ...  

Science.gov (United States)

... H1N1 a pandemic virus in June 2009, the Defense Advanced Research Projects Agency had a plan to address the crisis. The DARPA effort, called ...

10

2009 Flu Prevention PSA Contest | Flu.gov  

Science.gov (United States)

in cash and is featured on national television. Congratulations to Dr. John Clarke of Baldwin, New York for his video entitled H1N1 Rap by Dr. Clarke. Congrats to the Winning...

2011-09-21

11

Illinois department of public health H1N1/A pandemic communications evaluation survey.  

Energy Technology Data Exchange (ETDEWEB)

Because of heightened media coverage, a 24-hour news cycle and the potential miscommunication of health messages across all levels of government during the onset of the H1N1 influenza outbreak in spring 2009, the Illinois Department of Public Health (IDPH) decided to evaluate its H1N1 influenza A communications system. IDPH wanted to confirm its disease information and instructions were helping stakeholders prepare for and respond to a novel influenza outbreak. In addition, the time commitment involved in preparing, issuing, monitoring, updating, and responding to H1N1 federal guidelines/updates and media stories became a heavy burden for IDPH staff. The process and results of the ...

2010-09-16

12

Aerosol influenza transmission risk contours: A study of humid tropics versus winter temperate zone  

UK PubMed Central (United Kingdom)

BackgroundIn recent years, much attention has been given to the spread of influenza around the world. With the continuing human outbreak of H5N1 beginning in 2003 and the H1N1 pandemic...Full Text Available

13

Cutaneous gallium uptake in patients with AIDS with mycobacterium avium-intracellulare septicemia  

International Nuclear Information System (INIS)

Gallium imaging is increasingly being used for the early detection of complications in patients with AIDS. A 26-year-old homosexual man who was HIV antibody positive underwent gallium imaging for investigation of possible Pneumocystis carinii pneumonia. Widespread cutaneous focal uptake was seen, which was subsequently shown to be due to mycobacterium avium-intracellulare (MAI) septicemia. This case demonstrates the importance of whole body imaging rather than imaging target areas only, the utility of gallium imaging in aiding the early detection of clinically unsuspected disease, and shows a new pattern of gallium uptake in disseminated MAI infection.

15

Assessment of vesical-ureteral reflux in transplant patients using radionuclide cystography; Exploration scintigraphique des reflux vesico-renaux chez les patients transplantes renaux  

Energy Technology Data Exchange (ETDEWEB)

Direct radionuclide cystography is known to be sensitive and safe in children with suspected vesical-ureteral reflux. In this study we have investigated the utility of direct radionuclide cystography in renal transplant recipients with a recent history of pyelonephritis or recurrent urinary infections. Direct radionuclide cystography is a simple test, however it requires a rigorous methodology in order to obtain images during fill-in as well as during voiding in both men and women. The images must be interpreted using a rigorous image display methodology. Twenty-eight radionuclide cystographies were performed in 17 patients. Among the 17 tests performed for the initial diagnosis of reflux , 12 were positive. Four patients with positive results and four patients with negative results were also investigated by radiologic cystography. Similar results were obtained in those patients. Nine scintigraphies ...

1995-12-31

16

The treatment of diabetic foot infections: focus on ertapenem  

UK PubMed Central (United Kingdom)

Clinically, 3 distinct stages of diabetic foot infection may be recognized: localized infection, spreading infection and severe infection. Each of these presentations may be complicated by osteomyelitis....Full Text Available

2009-01-01

17

BUBL LINK: Skin cancer  

Wastenet

...CanCom Dermatology Image Bank Dermatology Online Atlas Introduction to Skin Cancer Malignant Melanoma Skin Cancer (Not Melanoma) Comments: bubl@bubl.ac.... Covers anatomy, melanoma, infections, and dermatological disorders in AIDS. Author: University of Utah ...994 Resource type: document Malignant Melanoma This leaflet on malignant melanoma covers early detection, causes, clinical signs and symptoms, and provides ...9 Resource type: document Skin Cancer (Not Melanoma) Information on basal cell and squamous cell skin cancers. Author: ...

18

MR imaging study on external hydrocephalus in infants: extracerebral space developmental and pathological enlargement  

International Nuclear Information System (INIS)

Objective: To analyze the characteristics of external hydrocephalus in infancy with MR imaging, and to explore the cause of accumulation of extracerebral fluid and the relation with brain development. Methods: Conventional magnetic resonance T_1 weighted imaging (T_1WI) and T_2 weighted imaging (T_2WI) were performed in 46 infants aged 2 years or younger with external hydrocephalus (EH), and the results were analyzed. They were divided into 7 age groups. The width of extractable space was measured on T_2WI and compared with normal standard. Results: EH mainly resulted from infection, subdural hematoma or subarachnoid hemorrhage, HIE, which were 67.4% (31/46 cases) of the cases; EH with unknown cause were 26.1% (12/46 cases). EH was mainly located at the foreside of cerebral convexity, of which 80.4% (37/46 cases )was predominantly in the subarachnoid space, 8.7% (4/46 cases) in subdural space, 10.9% was ...

2006-05-01

19

Percutaneous drainage of abdominal abcess  

Energy Technology Data Exchange (ETDEWEB)

The mortality in undrained abdominal abscesses is high with a mortality rate ranging between 45 and 100%. The outcome in abdominal abscesses, however, has improved due to advances in image guided percutaneous interventional techniques. The main indications for the catheter drainage include treatment or palliation of sepsis associated with an infected fluid collection, and alleviation of the symptoms that may be caused by fluid collections by virtue of their size, like pancreatic pseudocele or lymphocele. The single liver abscesses may be drained with ultrasound guidance only, whereas the multiple abscesses usually require computed tomography (CT) guidance and placement of multiple catheters. The pancreatic abscesses are generally drained routinely and urgently. Non-infected pancreatic pseudocysts may be simply observed unless they are symptomatic or cause problems such as pain or obstruction of the biliary or the ...

2002-09-01

20

Magnetic resonance imaging: early detection of central nervous system involvement in acquired immunodeficiency syndrome (AIDS)  

International Nuclear Information System (INIS)

Central Nervous System (CNS) involvement, whether primary by the Human Immunodeficiency Virus - HIV - itself, or secondary (toxoplasmosis or lymphoma) is remarkably frequent in AIDS, in 40 to 70% of cases, depending upon the author. In order to study the natural history of this illness, a cohort of 25 asymptomatic seropositive patients have been established. Every 6 months these patients undergo biological and clinical examinations, as well as Magnetic Resonance brain scans. After two examinations at a 6 month's interval, the first results are reported. Out of these 25 cases, 9 present anomalies: One patient with diffuse cerebral atrophy and 8 others with high signal intensity areas on T2 weighted sequences, like those of the Multiple Sclerosis. No relationship could be demonstrated between the existence of these lesions and various criteria such as age, sex, risk factors and T4 cells count. The nature of these lesions is not lear. They certainly indicate early involvement of the CNS ...

21

Adherence with isoniazid for prevention of tuberculosis among HIV-infected adults in South Africa  

UK PubMed Central (United Kingdom)

BackgroundTuberculosis (TB) is the most common opportunistic infection in HIV-infected adults in developing countries. Isoniazid (INH) is recommended for treatment of latent TB infection,...Full Text Available

22

Detection of aortoarterial graft infections by leukocyte scintigraphy  

Energy Technology Data Exchange (ETDEWEB)

Infections of aortoarterial prostheses are serious, difficult to detect, and difficult to treat. Scintigraphy with indium-111 labeled autologous leukocytes is an accurate noninvasive method of assessing the presence and extent of such an infection. In three cases of aorto-arterial bypass graft infections, the leukocyte study was successful in establishing the diagnosis and in assessing the extent of infection. Other noninvasive diagnostic techniques are useful, but all have serious limitations. The leukocyte study alone appears to be free of likely sources of error.

1983-09-01

23

Use of Cefoxitin, New Cephalosporin-Like Antibiotic, in the Treatment of Aerobic and Anaerobic Infections  

UK PubMed Central (United Kingdom)

Forty-two patients were treated with intravenous cefoxitin, a new cephamycin antibiotic. These patients had postoperative abdominal sepsis (26), intrathoracic infections (6), urinary tract infections...Full Text Available

1978-12-01

24

Theoretical Design of a Gene Therapy To Prevent AIDS but Not Human Immunodeficiency Virus Type 1 Infection  

UK PubMed Central (United Kingdom)

Recent reports confirm that, due to the presence of long-lived, latently infected cell populations, eradication of human immunodeficiency virus type 1 (HIV-1) from infected patients by using antiretroviral...Full Text Available

2003-09-01

25

The French national prospective cohort of patients co-infected with HIV and HCV (ANRS CO13 HEPAVIH): Early findings, 2006-2010  

UK PubMed Central (United Kingdom)

BackgroundIn France, it is estimated that 24% of HIV-infected patients are also infected with HCV. Longitudinal studies addressing clinical and public health questions related to...Full Text Available

26

Temporal trends in hepatitis B and C infection in family blood donors from interior Sindh, Pakistan  

UK PubMed Central (United Kingdom)

BackgroundHepatitis B (HBV) and C (HCV) infections are a serious global and national public health problem. Earlier studies have reported increasing rates of hepatitis infection...Full Text Available

27

Neonatal E. coli infection alters glial, cytokine, and neuronal gene expression in response to acute amphetamine in adolescent rats  

UK PubMed Central (United Kingdom)

Neonatal bacterial infection in rats alters the responses to a variety of subsequent challenges later in life. Here we explored the effects of neonatal bacterial infection on a subsequent drug...Full Text Available

2010-04-19

28

Misdiagnosed HIV infection in pregnant women: implications for clinical care.  

UK PubMed Central (United Kingdom)

Out of nearly 900 women in a research study of human immunodeficiency virus infection in pregnancy, 8 were subsequently found not to be infected. Misdiagnoses could have resulted from (a) laboratory...Full Text Available

1994-09-01

29

Impact of repeated four-monthly anthelmintic treatment on Plasmodium infection in preschool children: a double-blind placebo-controlled randomized trial  

UK PubMed Central (United Kingdom)

BackgroundHelminth infections can alter susceptibility to malaria. Studies need to determine whether or not deworming programs can impact on Plasmodium infections...Full Text Available

30

Genital HPV infection not a local but a regional infection: experience from a female teenage group.  

UK PubMed Central (United Kingdom)

OBJECTIVES--To investigate the prevalence of human papillomavirus (HPV) infections in a group of female teenagers, and to analyse to what extent HPV DNA was also detectable, in urethra and cervix samples...Full Text Available

1993-02-01

31

Evaluation of ceftriaxone and other antibiotics against Escherichia coli, Pseudomonas aeruginosa, and Streptococcus pneumoniae under in vitro conditions simulating those of serious infections.  

UK PubMed Central (United Kingdom)

In pursuit of an in vitro system capable of reliably predicting the activities of antibiotics in serious infections and in infections occurring in immunocompromised hosts, we evaluated the abilities...Full Text Available

1988-04-01

32

Diagnosis of Plasmodium falciparum infection using a solid-phase radioimmunoassay for the detection of malaria antigens  

UK PubMed Central (United Kingdom)

A serodiagnostic test has been developed for the detection of Plasmodium falciparum in infected blood. Using parasite antigens and infected red blood cells from in vitro...Full Text Available

1980-01-01

33

Characterization of antibodies mediating protection and cure of Trypanosoma musculi infection in mice.  

UK PubMed Central (United Kingdom)

Plasma samples were collected from mice infected with Trypanosoma musculi at different times postinfection and administered to naive recipient mice either before or during T. musculi infection. The...Full Text Available

1985-06-01

34

BK Virus and Human Cancer: Innocent until Proven Guilty  

UK PubMed Central (United Kingdom)

BK virus (BKV) is a polyomavirus that ubiquitously infects the human population. Following a typically subclinical primary infection, BKV establishes a lifelong persistent infection in the kidney...Full Text Available

2009-08-01

35

Activation of the alternate complement pathway in Staph. aureus infective endocarditis and its relationship to thrombocytopenia, coagulation abnormalities, and acute glomerulonephritis.  

UK PubMed Central (United Kingdom)

Twenty-four patients with infective endocarditis (IE) are described, fourteen with Staph. aureus and ten with other organisms. Despite the acute nature of the infection, ten of the fourteen with Staph....Full Text Available

1978-11-01

36

A Murine Model to Study the Antibacterial Effect of Copper on Infectivity of Salmonella Enterica Serovar Typhimurium  

UK PubMed Central (United Kingdom)

This study investigated the effect of copper as an antibacterial agent on the infectivity of Salmonella enterica serovar Typhimurium. Mice were infected orally with a standardized dose...Full Text Available

2011-01-01

37

Nosocomial Vaccinia Infection  

UK PubMed Central (United Kingdom)

Although hospital-associated spread of vaccinia has been reported in the past, there have been no recent reports. This paper describes hospital-associated spread of vaccinia virus infection, supplies...Full Text Available

1976-10-01

38

Legionella Pneumophila Transcriptome during Intracellular Multiplication in Human Macrophages  

UK PubMed Central (United Kingdom)

Legionella pneumophila is the causative agent of Legionnaires’ disease, an acute pulmonary infection. L. pneumophila is able to infect and multiply in both...Full Text Available

39

Efficacy of tilmicosin in the control of experimentally induced Actinobacillus pleuropneumoniae infection in swine  

UK PubMed Central (United Kingdom)

AbstractThe efficacy of tilmicosin administered in the feed to control Actinobacillus pleuropneumoniae infections in pigs was evaluated through a multisite, multitrial...Full Text Available

2004-01-01

40

Dyspepsia Symptoms and Helicobacter pylori Infection, Nakuru, Kenya  

UK PubMed Central (United Kingdom)

The prevalence of Helicobacter pylori infection was studied in 138 patients with dyspepsia in a hospital in Nakuru, Kenya, and in 138 asymptomatic sex- and age-matched controls from...Full Text Available

2003-09-01

41

Do pediatric emergency departments pose a risk of infection?  

UK PubMed Central (United Kingdom)

BackgroundThere is no data documenting the existence of a risk of infection transmission in ambulatory healthcare settings but concern remains. Our objective was to determine the...Full Text Available

43

Development of Intelligent Setting System for Fracture Based on X-Ray Image  

Energy Technology Data Exchange (ETDEWEB)

In order to achieve micro-wound, intelligence and high efficiency for fracture setting, intelligent setting system for fracture is proposed in accordance with biomechanics and fracture therapy theory. In the comprehensive medical system based on C-shape-arm X-machine, image processing and analysis is the core, programmable logical controller and stepping motor are important driving parts controlling mechanical parts. Six degree of freedom dynamics sensor ensures to control accurately force and moment. On the foundation of analyzing X-ray image peculiarities, method of processing and analysis is put forward, combining time domain with frequency domain. After mining domain knowledge in depth, setting actions is quantized into three non-continuous steps and is parameterized into two angles and one distance aiming at femoral-neck fracture. Objective features are extracted by virtue of three power polymerization curved surface fitting. Master-slave ...

2006-10-15

44

AIDS and lung infection by Mycobacterium xenopi. Role of Computed Tomography  

International Nuclear Information System (INIS)

Mycobacterium xenopi is one of the most common agents responsible for nontubercolar mycobacterial pulmonary disease on AIDS patients. These lesions have been studied with conventional radiography while CT has been used in patients with a specific mycobacterioses or non-AIDS pulmonary conditions from Mycobacterium xenopi. 12 AIDS patients were examined. They had pulmonary lesions from Mycobacterium xenopi, patients age ranged 30 to 46 years. All patients had CD4 blood levels lower than 250 cells/mL and Mycobacterium xenopi in the sputum. All patients underwent a standard chest radiograph and a CT examination. CT images were evaluated by three radiologists independently and the definitive diagnosis was made in the presence of a fourth radiologist. Chest CT showed parenchymal consolidation in 66% of cases, associated with bilateral basal bands in 16% of cases. Consolidation was unilateral in 41% of cases and most frequently involved the right lower lobe. Bilateral ...

2000-06-01

46

Protein expression in white spot syndrome virus infected Penaeus monodon fabricius.  

Science.gov (United States)

White spot syndrome virus (WSSV) is the causative agent of the white spot disease of shrimp. Penaeus monodon were captured from Muttukadu Estuary in Chennai, India, transported to the laboratory and maintained in an aerated system with continuous water circulation-biofiltration. WSSV-free P. monodon were challenged by feeding them only once with WSSV-infected tissues of P. monodon. Cumulative mortality (100%) of the infected individuals was determined. Tissues from infected and uninfected shrimp such as muscles, hepatopancreas, heart, gills and eye tissues (100mg of each) and haemolymph (50 microl) were subjected to SDS-PAGE. In infected muscle tissue, six newly expressed proteins were detected. In infected haemolymph, four new proteins and three intensely expressed high molecular weight proteins were observed. Three intensely expressed high molecular weight proteins were detected ...

2005-06-01

49

ELECTRON MICROSCOPE STUDIES INTO THE ...  

Science.gov (United States)

ELECTRON MICROSCOPE STUDIES INTO THE MORPHOLOGY AND LOCALIZATION OF OMSK HEMORRHAGIC FEVER VIRUS IN INFECTED ...

1966-08-01

51

Antimicrobials in the Management of Post-Irradiation Infection  

Science.gov (United States)

... develops. An alternative approach is the use of non-absorbable antibiot- ics such as polymyxin, neomycin, and bacitracin. ...

2011-05-13

52

Regulation of human ribosomal RNA transcription.  

Science.gov (United States)

We have used a cell-free polymerase I transcription system derived from HeLa cells to study the regulation of human rRNA synthesis. Analysis of deletion mutants spanning the start site of transcription at nucleotide +1 indicates that the control region affecting initiation of human rRNA synthesis is contained within sequences from nucleotides -158 to +18. This promoter region can be subdivided into (i) a central segment of approximately 40 base pair that is required for transcription and (ii) flanking sequences that influence the efficiency of transcription in vitro. We have examined the in vitro transcriptional activity of the human extract under various conditions that are thought to modulate rRNA synthesis in vivo. Cell-free extracts prepared from HeLa cells infected with adenovirus 2 synthesize human rRNA at levels greatly decreased relative to uninfected cell extracts. By contrast, in vitro transcription of human rRNA is stimulated 2- to 3-fold by the addition ...

1983-06-01

53

Atlas of nuclear medicine imaging  

Energy Technology Data Exchange (ETDEWEB)

An exhaustive compendium of normal and abnormal imaging is presented. The following systems and procedures are illustrated by over 2800 captioned illustrations: liver, spleen, and hepatobiliary imaging; perfusion and ventilation lung imaging; thyroid imaging; salivary gland imaging; bone imaging; brain imaging; radionuclide cisternography; blood flow studies; gallium imaging; nuclear cardiology; and renal imaging. Not included in the atlas are adrenal imaging procedures and emission computed tomography. (ERB)

1981-01-01

54

Computed Tomography in the study of pulmonary tuberculosis  

International Nuclear Information System (INIS)

The authors carried out a retrospective study on 4 years' work on a series of patients with proved active tuberculosis examined in the Departments of Bronchopneumology and Infectious Disease of the Arezzo Civil Hospital. The population was heterogenerous from the immunologic viewpoint. This paper compared the effectiveness of Computed Tomography (CT) with that of conventional chest radiography (CR) in the diagnosis and prognosis of tuberculosis. All patients underwent chest CR in double projection and conventional CT studies of the chest; 16 patients were also submitted to high resolution CT (HRCT). Consolidation was the most frequent parenchymal lesion in immunocompetent patients; it was often associated with cavitation, with no clear topographic prevalence in the upper lobes. Pleural effusion, as the only sign of disease and with empyema features, was found in 10 immunocompetent patients. No predominant pattern was found in the other two groups, even though intrathoracic adenopathies ...

1997-01-01

55

Management of septic complications following modular endoprosthetic reconstruction of the proximal femur  

British Library Electronic Table of Contents (United Kingdom)

In a retrospective single-centre study 170 consecutive patients were included who received a Kotz modular prosthesis after resection of bone tumours of the proximal femur to evaluate the management of prosthetic infection. Infection occurred in 12 of 166 patients available for follow-up (six males; six females; mean age, 47?years; range, ten to 75?years) after a mean of 39?months (range, one to 166?months; infection rate, 7.2%). Mean follow-up was 54?months (range, four to 200?months). One patient died of septic shock. Two patients were treated by wound revision only. Treatment of infection in the remaining patients was one-stage revision in eight and hip disarticulation in one. Infection control by one-stage revision was achieved in five of eight patients; re-infection occurred in three p...

2011-01-01

56

Comparative profiling of the transcriptional response to soybean cyst nematode infection of soybean roots by deep sequencing  

British Library Electronic Table of Contents (United Kingdom)

To gain insight into the changes in the transcriptome of soybean roots during soybean cyst nematode (SCN) infection, we conducted genome-wide gene expression profiling using serial analysis of gene expression (SAGE) combined with Solexa sequencing. More than 3 million tags were generated from the SCN-infected and uninfected roots, and 366941 and 314591 clean UniTags were obtained from SCN-infected and uninfected samples, respectively. In the SCN-infected sample, 48249 UniTags represented 18114 reference genes. In the uninfected control, 46290 UniTags represented 19323 reference genes. Comparison of tag frequencies identified 1405 genes that were expressed at greater levels in SCN-infected roots than in uninfected roots, and 1191 genes that were expressed at lower levels. Quantitative real-...

2011-01-01

57

Optical Images Due to Lenses and Mirrors  

Science.gov (United States)

... Title : Optical Images Due to Lenses and Mirrors. ... Abstract : The properties of real and virtual images formed by lenses and mirrors are reviewed. ...

59

MAGNETIC RESONANCE IMAGING DEVICE  

J-STORE (Japan)

Full Text Available

2010-08-31

60

Visual Genome-Wide RNAi Screening to Identify Human Host Factors Required for Trypanosoma cruzi Infection  

UK PubMed Central (United Kingdom)

The protozoan parasite Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical infection that affects millions of people in the Americas. Current chemotherapy...Full Text Available

61

Transmitted drug resistance in nonsubtype B HIV-1 infection  

UK PubMed Central (United Kingdom)

HIV-1 nonsubtype B variants account for the majority of HIV infections worldwide. Drug resistance in individuals who have never undergone antiretroviral therapy can lead to early failure and...Full Text Available

2009-09-01

62

The urine dipstick test useful to rule out infections. A meta-analysis of the accuracy  

UK PubMed Central (United Kingdom)

BackgroundMany studies have evaluated the accuracy of dipstick tests as rapid detectors of bacteriuria and urinary tract infections (UTI). The lack of an adequate explanation for...Full Text Available

63

The paradox of using a 7 day antibacterial course to treat urinary tract infections in the community.  

UK PubMed Central (United Kingdom)

1. We have studied determinants of outcome of 7 day courses of treatment in 77 middle aged and elderly patients, in whom the general practitioner's diagnosis of urinary tract infections had been confirmed...Full Text Available

1988-10-01

64

The inhibition of staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection  

UK PubMed Central (United Kingdom)

Peri-prosthetic infections are notoriously difficult to treat as the biomaterial implant is ideal for bacterial adhesion and biofilm formation, resulting in decreased antibiotic sensitivity....Full Text Available

2008-12-01

65

Synergism between Prior Anisakis simplex Infections and Intake of NSAIDs, on the Risk of Upper Digestive Bleeding: A Case-Control Study  

UK PubMed Central (United Kingdom)

BackgroundThe aim of this study was to investigate the relationship between prior Anisakis infections and upper gastrointestinal bleeding (UGIB), and its interaction...Full Text Available

66

Synchronous infection of SIV and HIV in vitro for virology, immunology, and vaccine-related studies  

UK PubMed Central (United Kingdom)

The development of an HIV vaccine will require a more precise understanding of the immunological and virological underpinnings of HIV infection. Magnetofection, the process of magnetizing HIV...Full Text Available

2010-01-01

67

Sustaining reductions in catheter related bloodstream infections in Michigan intensive care units: observational study  

UK PubMed Central (United Kingdom)

Objectives To evaluate the extent to which intensive care units participating in the initial Keystone ICU project sustained reductions in rates of catheter related bloodstream infections.Design...Full Text Available

2010-01-01

68

Susceptibility of human primary neuronal cells to Xenotropic Murine Leukemia Virus-related (XMRV) virus infection  

UK PubMed Central (United Kingdom)

BackgroundXenotropic Murine Leukemia Virus-related (XMRV) virus is a recently identified mouse gammaretrovirus that has the ability to infect certain human cells. In this study,...Full Text Available

69

Substance P Signaling Contributes to Granuloma Formation in Taenia crassiceps Infection, a Murine Model of Cysticercosis  

UK PubMed Central (United Kingdom)

Cysticercosis is an infection with larval cysts of the cestode Taenia solium. Through pathways that are incompletely understood, dying parasites initiate a granulomatous reaction that,...Full Text Available

2010-01-01

70

Serum Prohepcidin Levels in Helicobacter Pylori Infected Patients with Iron Deficiency Anemia  

UK PubMed Central (United Kingdom)

Background/AimsHelicobacter pylori (H. pylori) infection appears to subvert the human iron regulatory mechanism and thus upregulates hepcidin, resulting...Full Text Available

2010-06-01

71

SAMHD1: a new insight into HIV-1 restriction in myeloid cells  

UK PubMed Central (United Kingdom)

Human myeloid-lineage cells are refractory to HIV-1 infection. The Vpx proteins from HIV-2 and sooty mangabey SIV render these cells permissive to HIV-1 infection through proteasomal degradation of...Full Text Available

72

Ross River Virus Transmission, Infection, and Disease: a Cross-Disciplinary Review  

UK PubMed Central (United Kingdom)

Ross River virus (RRV) is a fascinating, important arbovirus that is endemic and enzootic in Australia and Papua New Guinea and was epidemic in the South Pacific in 1979 and 1980. Infection with RRV...Full Text Available

2001-10-01

73

Results of a multicenter trial comparing imipenem/cilastatin to tobramycin/clindamycin for intra-abdominal infections.  

UK PubMed Central (United Kingdom)

We designed a multicenter study to compare tobramycin/clindamycin to imipenem/cilastatin for intra-abdominal infections. We included the Acute Physiology and Chronic Health Evaluation (APACHE II) index...Full Text Available

1990-11-01

74

Randomized Controlled Trials of Interventions to Prevent Sexually Transmitted Infections: Learning From the Past to Plan for the Future  

UK PubMed Central (United Kingdom)

Globally, sexually transmitted infections (STIs) represent a significant source of morbidity and disproportionately impact the health of women and children. The number of randomized controlled trials...Full Text Available

2010-04-01

75

Proteome-wide Anti-HCV and Anti-HIV Antibody Profiling for Predicting and Monitoring Response to HCV Treatment in HIV Co-infected Patients  

UK PubMed Central (United Kingdom)

We quantified antibody responses to the HCV proteome that are associated with sustained virologic response (SVR) in HIV/HCV co-infected patients treated with pegylated interferon and ribavirin....Full Text Available

2010-09-15

76

Prospective Memory in HIV-1 Infection  

UK PubMed Central (United Kingdom)

The cognitive deficits associated with HIV-1 infection are thought to primarily reflect neuropathophysiology within the fronto-striato-thalamo-cortical circuits. Prospective memory (ProM) is...Full Text Available

2006-05-01

77

Prevalence of Erectile Dysfunction in HTLV-1 Infected Patients and its Association with Overactive Bladder  

UK PubMed Central (United Kingdom)

ObjectiveTo determine the prevalence of erectile dysfunction (ED) in HTLV-I infected patients, and its association with overactive bladder (OB).Full Text Available

2010-05-01

78

Polyantigenic Interferon-? Responses Are Associated with Protection from TB among HIV-Infected Adults with Childhood BCG Immunization  

UK PubMed Central (United Kingdom)

BackgroundSurrogate immunologic markers for natural and vaccine-mediated protection against tuberculosis (TB) have not been identified.MethodsHIV-infected...Full Text Available

79

Patient-Care Practices Associated With an Increased Prevalence Of Hepatitis C Virus Infection among Chronic Hemodialysis Patients  

UK PubMed Central (United Kingdom)

ObjectiveTo identify patient-care practices related to an increased prevalence of hepatitis C virus (HCV) infection among chronic hemodialysis patients.Full Text Available

2011-05-01

80

Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity  

UK PubMed Central (United Kingdom)

BackgroundSeasonal influenza A infection affects a significant cohort of the global population annually, resulting in considerable morbidity and mortality. Therapeutic strategies...Full Text Available

2011-05-01

81

Multiplicity of Plasmodium falciparum infection in asymptomatic children in Senegal: relation to transmission, age and erythrocyte variants  

UK PubMed Central (United Kingdom)

BackgroundIndividuals living in malaria endemic areas generally harbour multiple parasite strains. Multiplicity of infection (MOI) can be an indicator of immune status. However,...Full Text Available

82

Multiple integration sites for Moloney murine leukemia virus in productively infected mouse fibroblasts.  

UK PubMed Central (United Kingdom)

The integration sites for viral DNA in cells infected with Moloney murine leukemia virus (M-MuLV) were studied by restriction endonuclease cleavage of cellular DNA followed by electrophoresis in agarose...Full Text Available

1979-06-01

83

Meningococcal infections in the Hamilton area during 1978.  

UK PubMed Central (United Kingdom)

During 1978 there was a marked increase in the number of patients with meningococcal infection in the Hamilton area. Of 21 patients admitted to St. Joseph's Hospital, Hamilton, two thirds were under...Full Text Available

1980-03-08

84

Mechanism of Host Defense Suppression Induced by Viral Infection: Mode of Action of Inosiplex as an Antiviral Agent  

UK PubMed Central (United Kingdom)

The mechanism of influenza virus (INFV)-induced immunosuppression and the mode of inosiplex action against INFV infection were studied. INFV suppressed both anti-lipopolysaccharide and anti-sheep erythrocyte...Full Text Available

1982-10-01

85

Listeria monocytogenes Infection Induces Prosurvival Metabolic Signaling in Macrophages?  

UK PubMed Central (United Kingdom)

Host cells use metabolic signaling through the LXRα nuclear receptor to defend against Listeria monocytogenes infection. 25-Hydroxycholesterol is a natural ligand of LXRs that...Full Text Available

2011-04-01

86

Lethal Silver-Haired Bat Rabies Virus Infection Can Be Prevented by Opening the Blood-Brain Barrier?  

UK PubMed Central (United Kingdom)

Silver-haired bat rabies virus (SHBRV) infection induces a strong virus-specific immune response in the periphery of the host, but death is common due to the failure to open the blood-brain barrier...Full Text Available

2007-08-01

87

Inhibition of HIV-1 Infection in Ex Vivo Cervical Tissue Model of Human Vagina by Palmitic Acid; Implications for a Microbicide Development  

UK PubMed Central (United Kingdom)

BackgroundApproximately 80% of all new HIV-1 infections are acquired through sexual contact. Currently, there is no clinically approved microbicide, indicating a clear and...Full Text Available

88

Influence of parasite strain on chemotherapy of murine infections with schistosomiasis mansoni  

UK PubMed Central (United Kingdom)

The effectiveness of chemotherapy in human schistosomiasis varies from one area to another, and limited data from experimentally infected animals suggest inherent differences in the susceptibility...Full Text Available

1971-01-01

89

Infective arthritis secondary to bladder outflow obstruction.  

UK PubMed Central (United Kingdom)

We describe two cases of septic arthritis occurring in association with lower urinary tract infection in elderly men. In both cases the organism isolated from both the joint and the urine was Staphylococcus...Full Text Available

1990-12-01

90

Infection dynamics and clinical manifestations following experimental inoculation of gilts at 90 days of gestation with a low dose of porcine reproductive and respiratory syndrome virus  

UK PubMed Central (United Kingdom)

Understanding the dynamics of porcine reproductive and respiratory syndrome virus (PRRSV) vertical transmission is important to enhance the accuracy of monitoring protocols for endemically infected...Full Text Available

2009-10-01

91

Individual Predisposition, Household Clustering and Risk Factors for Human Infection with Ascaris lumbricoides: New Epidemiological Insights  

UK PubMed Central (United Kingdom)

BackgroundMuch of our current understanding of the epidemiology of Ascaris lumbricoides infections in humans has been acquired by analyzing worm count data. These...Full Text Available

92

Increased prevalence of Borrelia burgdorferi infections in Bernese Mountain Dogs: a possible breed predisposition  

UK PubMed Central (United Kingdom)

BackgroundGlomerulonephritis in dogs has been associated with B. burgdorferi infections. In Bernese Mountain Dogs with glomerulonephritis antibodies against B....Full Text Available

93

In vitro assay for curative activity in blood of mice infected with Trypanosoma musculi.  

UK PubMed Central (United Kingdom)

An in vitro assay for curative antibody present in plasma of mice cured of Trypanosoma musculi is described. The assay involves the addition of plasma to a sample of infected blood, followed by hourly...Full Text Available

1986-08-01

94

Impact of Long-Term Treatment with Ivermectin on the Prevalence and Intensity of Soil-Transmitted Helminth Infections  

UK PubMed Central (United Kingdom)

BackgroundControl of soil-transmitted helminth (STH) infections relies on the periodic and long-term administration of anthelmintic drugs to high-risk groups, particularly school-age...Full Text Available

95

Identification of immune genes and proteins involved in the response of bovine mammary tissue to Staphylococcus aureus infection  

UK PubMed Central (United Kingdom)

BackgroundMastitis in dairy cattle results from infection of mammary tissue by a range of micro-organisms but principally coliform bacteria and Gram positive bacteria such as Staphylococcus...Full Text Available

96

IL-6-Dependent Mucosal Protection Prevents Establishment of a Microbial Niche for Attaching/Effacing Lesion-Forming Enteric Bacterial Pathogens1  

UK PubMed Central (United Kingdom)

Enteric infections with attaching/effacing lesion-inducing bacterial pathogens are a worldwide health problem. A murine infection model with one such pathogen, Citrobacter rodentium,...Full Text Available

2008-05-15

97

Human papillomavirus infection in Beijing, People's Republic of China: a population-based study  

UK PubMed Central (United Kingdom)

Background:No recent data exist on human papillomavirus (HPV) infection in Beijing, People's Republic of China.Materials and methodWe interviewed...Full Text Available

2009-11-03

98

Human papillomavirus infection and anal carcinoma. Retrospective analysis by in situ hybridization and the polymerase chain reaction.  

UK PubMed Central (United Kingdom)

To examine the association of human papillomavirus (HPV) infection with anal squamous cell carcinoma, the authors applied the highly sensitive polymerase chain reaction (PCR) and in situ hybridization...Full Text Available

1992-06-01

99

Hepatitis B virus infection and primary hepatocellular carcinoma.  

UK PubMed Central (United Kingdom)

For many years, epidemiological studies have demonstrated a strong link between chronic hepatitis B virus (HBV) infection and the development of primary hepatocellular carcinoma (PHC). Other hepatocarcinogens...Full Text Available

1992-07-01

100

Hepatitis B virus infection among different sex and age groups in Pakistani Punjab  

UK PubMed Central (United Kingdom)

BackgroundHepatitis B virus (HBV) infection is a serious health problem in the developing countries including Pakistan. Various risk factors are responsible for the spread of this...Full Text Available

101

Genetic Polymorphism of Cancer Susceptibility Genes and HPV Infection in Cervical Carcinogenesis  

UK PubMed Central (United Kingdom)

It is widely accepted that specific human papillomavirus (HPV) types are the central etiologic agent of cervical carcinogenesis. However, a number of infected women do not develop invasive lesions,...Full Text Available

102

From Attachment to Damage: Defined Genes of Candida albicans Mediate Adhesion, Invasion and Damage during Interaction with Oral Epithelial Cells  

UK PubMed Central (United Kingdom)

Candida albicans frequently causes superficial infections by invading and damaging epithelial cells, but may also cause systemic infections by...Full Text Available

103

Experimental infection of Foxes with European bat Lyssaviruses type-1 and 2  

UK PubMed Central (United Kingdom)

BackgroundSince 1954, there have been in excess of 800 cases of rabies as a result of European Bat Lyssaviruses types 1 and 2 (EBLV-1, EBLV-2) infection, mainly...Full Text Available

104

Enhancing Patient Safety by Reducing Healthcare-Associated Infections: The Role of Discovery and Dissemination  

UK PubMed Central (United Kingdom)

Healthcare-associated infections (HAIs) take a major human toll on society and reduce public confidence in the healthcare system. The current convergence of scientific, public, and legislative...Full Text Available

2010-02-01

105

Effects of bovine leukemia virus infection on production and reproduction in dairy cattle.  

UK PubMed Central (United Kingdom)

The purpose of this study was to determine the effects of bovine leukemia virus (BLV) infection on production, reproduction and longevity in dairy cattle. The study population was a commercial Holstein...Full Text Available

1992-10-01

106

Disruption of Putative Regulatory Loci in Listeria monocytogenes Demonstrates a Significant Role for Fur and PerR in Virulence  

UK PubMed Central (United Kingdom)

The ability to adapt to adverse environmental conditions encountered in food and during host infection is a sine qua non for a successful Listeria monocytogenes infection. This ability...Full Text Available

2004-02-01

107

Desmozoon lepeophtherii n. gen., n. sp., (Microsporidia: Enterocytozoonidae) infecting the salmon louse Lepeophtheirus salmonis (Copepoda: Caligidae)  

UK PubMed Central (United Kingdom)

BackgroundA microsporidian was previously reported to infect the crustacean parasite, Lepeophtheirus salmonis (Krøyer, 1837) (Copepoda, Caligidae), on farmed...Full Text Available

108

Decreased respiratory quotient in relation to resting energy expenditure in HIV-infected and non-infected subjects  

UK PubMed Central (United Kingdom)

The purpose of this study was to evaluate the relationship of respiratory quotient (RQ), a surrogate marker of substrate oxidation, as well as body composition and dietary intake to resting...Full Text Available

2009-05-01

109

Conventional Linear versus Purse-string Skin Closure after Loop Ileostomy Reversal: Comparison of Wound Infection Rates and Operative Outcomes  

UK PubMed Central (United Kingdom)

PurposeWound infection after an ileostomy reversal is a common problem. To reduce wound-related complications, purse-string skin closure was introduced as an alternative to conventional...Full Text Available

2011-04-01

110

Control of intestinal parasitic infections in Seychelles: a comprehensive and sustainable approach.  

UK PubMed Central (United Kingdom)

Intestinal parasitic infections have been perceived as a public health problem in Seychelles for decades. A comprehensive strategy to reduce morbidity and, in the long term, transmission of intestinal...Full Text Available

1996-01-01

111

Comparison of a Commercial Multiplex Real-Time PCR to the Cell Cytotoxicity Neutralization Assay for Diagnosis of Clostridium difficile Infections?  

UK PubMed Central (United Kingdom)

A commercial multiplex real-time PCR assay (Cepheid Xpert C. difficile assay) for the diagnosis of Clostridium difficile infection was evaluated. The sensitivity and...Full Text Available

2009-11-01

112

Circulating Matrix Metalloproteinases in Infective Endocarditis: A Possible Marker of the Embolic Risk  

UK PubMed Central (United Kingdom)

BackgroundEmbolic events (EE) in infective endocarditis (IE) are caused by fragmentation of vegetations or valvular tissue. Vegetation length is considered to be the most potent...Full Text Available

113

Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil  

UK PubMed Central (United Kingdom)

In world Helminthes infections are the most widespread of all the infections in humans. The morbidity due to parasitic diseases has been increasing in our population. The gastrointestinal helminthes...Full Text Available

2010-05-01

114

Chlamydial urethral infection in Teheran. A study of male patients attending an STD clinic.  

UK PubMed Central (United Kingdom)

The prevalence of chlamydial infection of the urethra was studied in 172 consecutive male patients attending a sexually transmitted disease clinic in Teheran. Chlamydia trachomatis was isolated in 8.8%...Full Text Available

1982-12-01

115

Characterization of the Molecular Mechanism of Defective Interfering RNA-Mediated Symptom Attenuation in Tombusvirus-Infected Plants  

UK PubMed Central (United Kingdom)

Different tombusviruses were able to support the replication of either homologous or heterologous defective interfering (DI) RNAs, and those infected plants usually developed typical attenuated symptoms....Full Text Available

1998-07-01

116

CTX-M ?-Lactamases in Escherichia coli from Community-acquired Urinary Tract Infections, Cambodia  

UK PubMed Central (United Kingdom)

Despite the recent global spread of CTX-M β-lactamases in Escherichia coli isolates from community-acquired urinary tract infections (CA-UTIs), their dissemination has been...Full Text Available

2009-05-01

117

Bone Disease in HIV Infection: A Practical Review and Recommendations for HIV Care Providers  

UK PubMed Central (United Kingdom)

Low bone mineral density (BMD) is prevalent in human immunodeficiency virus (HIV)–infected subjects. Initiation of antiretroviral therapy is associated with a 2%–6% decrease...Full Text Available

2010-10-15

118

Asymptomatic gonorrhoea and chlamydial infection in rural Tanzanian men.  

UK PubMed Central (United Kingdom)

OBJECTIVE: To measure the prevalence of urethritis due to Neisseria gonorrhoeae and Chlamydial infection trachomatis in rural Tanzanian men DESIGN: About 500 men aged 15-54 years were selected from...Full Text Available

1996-02-03

119

Association of Nasophyaryngeal Bacterial Colonization during Upper Respiratory Tract Infection and the Development of Acute Otitis Media  

UK PubMed Central (United Kingdom)

Acute Otitis Media occurs mostly after upper respiratory tract infection; the causative bacteria are those colonized in the nasopharynx. We studied 709 URI episodes and found that children with...Full Text Available

2008-02-15

120

Association between skin diseases and severe bacterial infections in children: case-control study  

UK PubMed Central (United Kingdom)

BackgroundSepsis or bacteraemia, however rare, is a significant cause of high mortality and serious complications in children. In previous studies skin disease or skin infections...Full Text Available

121

Association between bacterial vaginosis or chlamydial infection and miscarriage before 16 weeks' gestation: prospective community based cohort study  

UK PubMed Central (United Kingdom)

ObjectivesTo assess whether bacterial vaginosis or chlamydial infection before 10 weeks' gestation is associated with miscarriage before 16 weeks.DesignProspective...Full Text Available

2002-12-07

122

Aspirin Treatment of Mice Infected with Trypanosoma cruzi and Implications for the Pathogenesis of Chagas Disease  

UK PubMed Central (United Kingdom)

Chagas disease, caused by infection with Trypanosoma cruzi, is an important cause of cardiovascular disease. It is increasingly clear that parasite-derived prostaglandins potently modulate...Full Text Available

123

Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing).  

UK PubMed Central (United Kingdom)

The mammalian reoviruses have provided a valuable model for studying the pathogenesis of viral infections of the central nervous system (CNS). We have used this model to study the effect of antibody...Full Text Available

1988-12-01

124

Accumulation of Plasmodium berghei-Infected Red Blood Cells in the Brain Is Crucial for the Development of Cerebral Malaria in Mice?  

UK PubMed Central (United Kingdom)

Cerebral malaria is the most severe complication of human infection with Plasmodium falciparum. It was shown that Plasmodium berghei ANKA-induced cerebral malaria was...Full Text Available

2010-09-01

125

ABO blood group phenotypes influence parity specific immunity to Plasmodium falciparum malaria in Malawian women  

UK PubMed Central (United Kingdom)

BackgroundBlood group O has been significantly associated with increased placental malaria infection in primiparae and reduced risk of infection in multiparae in the Gambia, an area...Full Text Available

126

A population pharmacokinetic meta-analysis of maraviroc in healthy volunteers and asymptomatic HIV-infected subjects  

UK PubMed Central (United Kingdom)

AimsTo develop a population pharmacokinetic model for maraviroc, a noncompetitive CCR5 antagonist, after oral administration of tablets to healthy volunteers and asymptomatic HIV-infected...Full Text Available

2008-04-01

127

A Simple, Versatile and Sensitive Cell-Based Assay for Prions from Various Species  

UK PubMed Central (United Kingdom)

Detection and quantification of prion infectivity is a crucial step for various fundamental and applied aspects of prion research. Identification of cell lines highly sensitive to prion infection led...Full Text Available

128

Neuroinflammation and brain infections: Historical context and current perspectives  

British Library Electronic Table of Contents (United Kingdom)

An overview of current concepts on neuroinflammation and on the dialogue between neurons and non-neuronal cells in three important infections of the central nervous systems (rabies, cerebral malaria, and human African trypanosomiasis or sleeping sickness) is here presented. Large numbers of cases affected by these diseases are currently reported. In the context of an issue dedicated to Camillo Golgi, historical notes on seminal discoveries on these diseases are also presented. Neuroinflammation is currently closely associated with pathogenetic mechanisms of chronic neurodegenerative diseases. Neuroinflammatory signaling in brain infections is instead relatively neglected in the neuroscience community, despite the fact that the above infections provide paradigmatic examples of alterations o...

2011-01-01

129

Evidence-Based Drainage of Infected Hydronephrosis Secondary to Ureteric Calculi  

British Library Electronic Table of Contents (United Kingdom)

Abstract Introduction: The obstructed, infected kidney is a urological emergency. It has been accepted that the management of infected hydronephrosis secondary to ureteric stones is through prompt decompression of the collecting system. However, the optimal method of decompression has yet to be established. Materials and Methods: A PubMed and Medline search was performed of all English-language articles from 1960 using key words ?sepsis,?? ?urosepsis,?? ?obstruction,?? ?obstructive pyelonephritis,?? ?pyonephrosis,?? ?infection and hydronephrosis?? ?decompression,?? ?stent,?? ?nephrostomy,?? and ?management.?? The Cochrane database and National Institute for Clinical Effectiveness guidelines were searched using the terms ?sepsis,?? ?urosepsis,?? ?stent,?? ?nephrostomy,?? or ?obstruction.?? ...

2010-01-01

131

Viral suppression of multiple escape mutants by de novo CD8+ T cell responses in a human immunodeficiency virus-1 Infected elite suppressor  

UK PubMed Central (United Kingdom)

Elite suppressors or controllers (ES) are HIV-1 infected patients who maintain undetectable viral loads without treatment. While HLA-B*57-positive ES are usually infected with virus that is unmutated...Full Text Available

132

The Effect of Circumcision of HIV-Infected Men on Human Papillomavirus Infection in Female Partners: Analyses Using Data from a Randomized Trial in Rakai, Uganda  

UK PubMed Central (United Kingdom)

BackgroundMale circumcision (MC) reduces high-risk human papillomavirus (HR-HPV) in HIV-uninfected men and their female partners. We assessed whether MC of HIV-infected...Full Text Available

2011-08-01

133

The Changing Face of Pediatric Respiratory Tract Infections: How Human Metapneumovirus and Human Bocavirus Fit into the Overall Etiology of Respiratory Tract Infections in Young Children  

UK PubMed Central (United Kingdom)

Lower respiratory tract infections are one of the leading causes of morbidity and mortality in children worldwide. Recent technological advances in the field of molecular biology have allowed virologists...Full Text Available

2010-12-01

134

Staphylococcus aureus Enterotoxin D Is Secreted in Milk and Stimulates Specific Antibody Responses in Cows in the Course of Experimental Intramammary Infection  

UK PubMed Central (United Kingdom)

An enterotoxin D (SED)-producing strain of Staphylococcus aureus was used to infect one mammary gland of each of 17 lactating dairy cows. All glands became infected and shed bacteria...Full Text Available

2006-06-01

135

Malaria and other vector-borne infection surveillance in the U.S. Department of Defense Armed Forces Health Surveillance Center-Global Emerging Infections Surveillance program: review of 2009 accomplishments  

UK PubMed Central (United Kingdom)

Vector-borne infections (VBI) are defined as infectious diseases transmitted by the bite or mechanical transfer of arthropod vectors. They constitute a significant proportion of the global infectious...Full Text Available

136

Differential Changes in Heat Shock Protein-, Lipoarabinomannan-, and Purified Protein Derivative-Specific Immunoglobulin G1 and G2 Isotype Responses during Bovine Mycobacterium avium subsp. paratuberculosis Infection  

UK PubMed Central (United Kingdom)

Bovine paratuberculosis is caused by infection of young calves with Mycobacterium avium subsp. paratuberculosis. In some of the chronically infected cows the long asymptomatic...Full Text Available

2001-03-01

137

Both the Fas Ligand and Inducible Nitric Oxide Synthase Are Needed for Control of Parasite Replication within Lesions in Mice Infected with Leishmania major whereas the Contribution of Tumor Necrosis Factor Is Minimal  

UK PubMed Central (United Kingdom)

Following infection with the protozoan parasite Leishmania major, C57BL/6 mice develop a small lesion that heals spontaneously. Resistance to infection is associated with the development...Full Text Available

2003-09-01

138

Toll-like receptor 2 polymorphism and gram-positive bacterial infections after liver transplantation  

British Library Electronic Table of Contents (United Kingdom)

Abstract Toll-like receptor 2 (TLR2) is an immune sensor for gram-positive bacterial cell wall components. Single-nucleotide polymorphisms (SNPs) in the TLR2 gene that impair its function may, therefore, influence the risk and outcomes of gram-positive bacterial infections. In a cohort of 694 liver transplant recipients, we assessed the TLR2 SNP that is translated into an amino acid substitution of arginine for glutamine at position 753 (R753Q), and we found that its presence was associated with the clinical characteristics and outcomes of gram-positive bacterial infections. The proportions of patients with the TLR2 R753Q SNP did not significantly differ between those with gram-positive bacterial infections and those without gram-positive bacterial infections (9.6% versus 9.6%, P = 0.999)....

2011-01-01

139

The genetics and evolution of obligate reproductive parasitism in Trichogramma pretiosum infected with parthenogenesis-inducing Wolbachia  

British Library Electronic Table of Contents (United Kingdom)

Parthenogenesis-inducing (PI) Wolbachia belong to a class of intracellular symbionts that distort the offspring sex ratio of their hosts toward a female bias. In many PI Wolbachia-infected species sex ratio distortion has reached its ultimate expression-fixation of infection and all-female populations. This is only possible with thelytokous PI symbionts as they provide an alternative form of reproduction and remove the requirement for males and sexual reproduction. Many populations fixed for PI Wolbachia infection have lost the ability to reproduce sexually, even when cured of the infection. We examine one such population in the species Trichogramma pretiosum. Through a series of backcrossing experiments with an uninfected Trichogramma pretiosum population we were able to show that the gen...

2011-01-01

140

PREVENTION OF INFECTION IN PATIENTS WITH CHRONIC KIDNEY DISEASE PART III: SURVEILLANCE AND AUDITING IN A RENAL CARE ENVIRONMENT  

British Library Electronic Table of Contents (United Kingdom)

Summary This third paper, in a three-part CE series on the preventions of infection in patients with chronic kidney disease, focuses on surveillance and auditing of healthcare-associated infections within the renal care environment. The last decade has seen an increased awareness of the threat to patient safety from healthcare-associated infection (HCAI) and the emergence of multi-drug resistance organisms. Effective HCAI prevention strategies include adequate governance structures, access to expert advice, adherence to standard and transmission-based precautions, minimising the use of invasive medical devices, and surveillance. Surveillance data can be collected using outcome (e.g. infection) and/or process (e.g. hand hygiene compliance audit) measures. Establishing a surveillance program...

2011-01-01

141

Mannose-binding lectin codon 54 gene polymorphism in relation to risk of nosocomial invasive fungal infection in preterm neonates in the neonatal intensive care unit  

British Library Electronic Table of Contents (United Kingdom)

Objective. Preterm neonates are susceptible to infection due to a combination of sub-optimal immunity and increased exposure to invasive organisms. Invasive fungal infections are associated with significant morbidity and mortality among preterm infants cared for in the neonatal intensive care unit (NICU). Mannose-binding lectin (MBL) is a component of the innate immune system, which may be especially important in the neonatal setting. The objective of this study was to investigate the presence of any association between MBL gene polymorphism and nosocomial invasive fungal infection in preterm neonates. Methods. Codon 54 (B allele) polymorphism in exon 1 of the MBL gene was investigated in 31 patients diagnosed as nosocomial invasive fungal infection and 30 control preterm neonates. Results...

2011-01-01

142

Herpesvirus saimiri infection of rhesus macaques: A model for acute rhadinovirus-induced t-cell transformation and oncogenesis  

British Library Electronic Table of Contents (United Kingdom)

Abstract Herpesvirus saimiri (HVS) causes acute lymphoma and leukemia upon experimental infection of various monkey species. HVS strain C488 is also capable of transforming human T-lymphocytes to stable growth in culture. The most susceptible species for oncogenesis are New World primates, in particular the cottontop tamarin (Saguinus oedipus). However, Old World monkeys such as macaques are the most used animal model for the close-to-human situation. The limited data on HVS infection in Old World monkeys prompted us to investigate susceptibility to infection and disease induction by HVS in macaques. After having established that rhesus macaques can be infected productively, and that rhesus T-cells can be transformed in vivo by HVS, we observed induction of lymphoma in all inoculated anima...

2011-01-01

143

Experimental bovine trypanosomiasis. Changes in serum immunoglobulins, complement and complement components in infected animals.  

Science.gov (United States)

In three calves experimentally infected with Trypanosoma congolense the amounts of IgG1 and IgG2 were little changed and similar to those of normal animals. IgM increased in amount early in the infection and the amount of the increase appeared related to the parasite burden. The amounts of IgA and IgE were both much decreased and this also appeared related to the numbers of parasites in the blood. There was a decrease in the amounts of total haemolytic complement and complement components C1, C1q and C3 in the infected calves. Furthermore the amounts of properdin fluctuated with the cyclical changes in numbers of T. congolense parasites in the individual calves. No significant change in the amount of C8 was observed. It is considered that activation of both the alternative and the classical complement pathways occurs in trypanosome infected animals but that neither pathway goes to its terminal stages.

1978-11-01

144

Anti-Infection Dip Suggestions for the Coloplast Titan Inflatable Penile Prosthesis in the Era of the Infection Retardant Coated Implant  

British Library Electronic Table of Contents (United Kingdom)

Abstract Introduction.- Infection is the worst complication seen with inflatable penile prosthesis (IPP). Both the American Medical Systems (AMS) and Coloplast IPP have infection retardant coatings. AMS is coated at the factory with rifampicin and minocycline (InhibiZone). The Coloplast IPP has a hydrophilic coating covalently bonded to its components that will absorb any aqueous solution before implantation and provides increased surface lubricity to decrease bacterial adherence. Aim.- We tested several antibiotic dips comparing zones of inhibition (ZOI) against five commonly infecting bacteria with coated Coloplast implants. Results were compared with those ZOI created with strips of an AMS IPP precoated with InhibiZone. Methods.- Pieces of sterile Coloplast Titan IPP were dipped in (i) ...

2011-01-01

147

Java Image I/O for VICAR, PDS, and ISIS  

Science.gov (United States)

This library, written in Java, supports input and output of images and metadata (labels) in the

2011-01-01

148

A non-local approach for image super-resolution using intermodality priors ?  

UK PubMed Central (United Kingdom)

Image enhancement is of great importance in medical imaging where image resolution remains a crucial point in many image analysis algorithms. In this paper, we investigate brain hallucination...Full Text Available

2010-08-01

149

Infected nonunion of the long bones.  

Science.gov (United States)

BACKGROUND: Although definitions vary, infected nonunion has been defined as a state of failure of union and persistence of infection at the fracture site for 6 to 8 months.>). Infected nonunions of the supracondylar region of the femur are uncommon and are mostly due to a severe open fracture with extensive comminution and segmental bone loss or after internal fixation of a comminuted closed fracture. Associated factors include exposed bone devoid of vascularized periosteal coverage for more than 6 weeks, purulent discharge, a positive bacteriological culture from the depth of the wound, and histologic evidence of necrotic bone containing empty lacunae. Soft-tissue loss with multiple sinuses, osteomyelitis, osteopenia, complex deformities with limb-length inequality, stiffness of the adjacent joint, polybacterial multidrug-resistant infection, and smoking all complicate treatment and recovery. ...

2007-08-01

150

Comparative analysis of budded virus infectivity of Bombyx mandarina and B. mori nucleopolyhedroviruses.  

Science.gov (United States)

Bombyx mandarina nucleopolyhedrovirus (BomaNPV) is a variant of Bombyx mori nucleopolyhedrovirus (BmNPV). BomaNPV S1 strain has been reported to be significantly less virulent than the BmNPV T3 strain via the oral infection route in B. mori larvae, but other features of S1 including budded virus (BV) infectivity and virus propagation in cultured cells are still unknown. In this study, we compared BV infectivity of S1 and T3 in B. mori larvae and cultured cells. Larval bioassays by intrahemocoelic BV injection revealed that the median lethal dose of S1's BV was approximately three times lower than that of T3. In addition, S1 produced more BVs and occlusion bodies (OBs) in the hemolymph of B. mori larvae compared with T3. Furthermore, we observed that the locomotion was enhanced earlier and the median lethal time was shorter in S1-infected larvae compared with those in T3-infected ...

2011-05-22

151

View larger image for ISS022-E-26137 - Earth Sciences and Image ...  

Science.gov (United States)

The Asarco-Mission complex (image left) is an active producer of copper and molybdenum (important in making steel and other metal alloys), ...

152

Digital processing to improve image quality in real-time neutron radiography  

Energy Technology Data Exchange (ETDEWEB)

Real-time neutron radiography (NTV) has been used for practical applications at the Kyoto University Reactor (KUR). At present, however, the direct image from the TV system is still poor in resolution and low in contrast. In this paper several image improvements are demonstrated, such as a frame summing technique, which are effective in increasing image quality in neutron radiography. Image integration before the A/D converter has a beneficial effect on image quality and the high quality image reveals details invisible in direct images, such as: small holes by a reversed image, defects in a neutron converter screen through a high quality image, a moving object in a contoured image, a slight difference between two low-contrast images by a subtraction ...

1985-01-01

153

Digital processing to improve image quality in real-time neutron radiography  

International Nuclear Information System (INIS)

Real-time neutron radiography (NTV) has been used for practical applications at the Kyoto University Reactor (KUR). At present, however, the direct image from the TV system is still poor in resolution and low in contrast. In this paper several image improvements are demonstrated, such as a frame summing technique, which are effective in increasing image quality in neutron radiography. Image integration before the A/D converter has a beneficial effect on image quality and the high quality image reveals details invisible in direct images, such as: small holes by a reversed image, defects in a neutron converter screen through a high quality image, a moving object in a contoured image, a slight difference between two low-contrast images by a subtraction ...

1985-01-01

154

Advances in Imaging of Vertebral and Spinal Cord Injury  

UK PubMed Central (United Kingdom)

Background/Objectives:Imaging technology is an important part of the diagnosis and management of spinal trauma. Indications and findings in post-traumatic imaging of the vertebral...Full Text Available

2010-04-01

155

3 - NASA Technical Report Server (NTRS)  

Science.gov (United States)

performs Gaussian pyramid operation on an image performs expand pyramid operation on an image mosaic two images using 'reduce' and 'expand' pyramid ...

156

(Hadamard transform imaging)  

Science.gov (United States)

This report describes the design of, and image reconstruction capacity of a Hadamard Raman Microscopic imager. Microscopy of benzoic acid and graphite electrodes, as well as electrophoretic blotting, are described. (CBS)

1990-01-01

157

Viruses and thyroiditis: an update  

UK PubMed Central (United Kingdom)

Viral infections are frequently cited as a major environmental factor involved in subacute thyroiditis and autoimmune thyroid diseases This review examines the data related to the role of viruses in...Full Text Available

158

Trimethoprim sulphamethoxazole in neonatal Flavobacterium meningosepticum infection.  

UK PubMed Central (United Kingdom)

During an outbreak of Flavobacterium meningosepticum septicaemia in a neonatal intensive care unit 9 infants were treated with intravenous trimethoprim sulphamethoxazole. Bacteriological cure was achieved...Full Text Available

1984-06-01

159

Tobacco-induced alterations to Porphyromonas gingivalis-host interactions  

UK PubMed Central (United Kingdom)

SUMMARYSmokers are more susceptible than non-smokers to persistent infection by Porphyromonas gingivalis, a causative agent of periodontitis. Patients who smoke...Full Text Available

2009-05-01

160

Rifampin Combination Therapy for Nonmycobacterial Infections  

UK PubMed Central (United Kingdom)

Summary: The increasing emergence of antimicrobial-resistant organisms, especially methicillin-resistant Staphylococcus aureus (MRSA), has resulted in the increased...Full Text Available

2010-01-01

161

Reduction in incidence of deep sternal wound infections: Random or real?  

British Library Electronic Table of Contents (United Kingdom)

Objective Comorbidities predisposing cardiac surgical patients toward deep sternal wound infection, such as diabetes and obesity, are rising in the United States. Longitudinal analysis of risk factors, morbidity, and mortality was performed to assessed effects of these health trends on deep sternal wound infection rates. Methods In this retrospective analysis of all median sternotomies performed at a single institution from 1991 through 2006, demographic and surgical characteristics were identified from a prospective database. The cohort was separated into periods from 1992 through 2001 and 2002 through 2006 to identify longitudinal trends in risk factors for deep sternal wound infection. Univariate and matched multivariable analyses were performed. Results Overall, study population had in...

2010-01-01

162

Recurrent corneal ulceration in presence of synthetic microfibrils  

UK PubMed Central (United Kingdom)

Recurrence of microbial keratitis in the presence of protozoal infection is very rare and infrequently reported unless predisposing factors are present. The association of recurrent microbial keratitis...Full Text Available

2011-01-01

163

Probiotic-Induced Priming of Innate Immunity to Protect Against Rotaviral Infection  

British Library Electronic Table of Contents (United Kingdom)

Understanding of probiotic-induced regulatory gene expression and networking is critical to further explore their roles in controlling infection. Transcriptional profile of selected innate immune genes in primary bovine intestinal epithelial cells was assessed over a time course of incubation with the probiotic Lactobacillus plantarum 299v. Based on gene expression results, a time point was chosen to prime epithelial cells with the probiotic prior to infection with rotavirus. Plaque assays and genomic analysis provided the basis for establishing the efficacy of probiotics in preventing a rotaviral infection. Plaque assays revealed that the probiotic is capable of decreasing (at least by 100-fold) the levels of live virus when the cells were primed with the probiotic. Results from gene expr...

2010-01-01

164

Prevalence-Dependent Costs of Parasite Virulence  

UK PubMed Central (United Kingdom)

Costs of parasitism are commonly measured by comparing the performance of infected groups of individuals to that of uninfected control groups. This measure potentially underestimates the cost of parasitism...Full Text Available

2005-08-01

165

Phylogenomic analyses of malaria parasites and evolution of their exported proteins  

UK PubMed Central (United Kingdom)

BackgroundPlasmodium falciparum is the most malignant agent of human malaria. It belongs to the taxon Laverania, which includes other ape-infecting Plasmodium...Full Text Available

166

Photorhabdus luminescens genes induced upon insect infection  

UK PubMed Central (United Kingdom)

BackgroundPhotorhabdus luminescens is a Gram-negative luminescent enterobacterium and a symbiote to soil nematodes belonging to the species Heterorhabditis...Full Text Available

167

PHENOTYPIC MODIFICATION OF ROACH (RUTILUS RUTILUS L.) INFECTED WITH LIGULA INTESTINALIS L. (CESTODA: PSEUDOPHYLLIDEA)  

Science.gov (United States)

... growth hormone-like factor from plerocercoids of the tapeworm Spirometra mansonoides is a multifunctional protein. In Parasites and pathogens: ... ...

168

Non-toxigenic Clostridium sordellii: Clinical and microbiological features of a case of cholangitis-associated bacteremia  

British Library Electronic Table of Contents (United Kingdom)

Toxigenic Clostridium sordellii strains are increasingly recognized to cause highly lethal infections in humans that are typified by a toxic shock syndrome (TSS). Two glucosylating toxins, lethal toxin (TcsL) and hemorrhagic toxin (TcsH) are believed to be important in the pathogenesis of TSS. While non-toxigenic strains of C. sordellii demonstrate reduced cytotoxicity in vitro and lower virulence in animal models of infection, there are few data regarding their behavior in humans. Here we report a non-TSS C. sordellii infection in the context of a polymicrobial bacterial cholangitis. The C. sordellii strain associated with this infection did not carry either the TcsL-encoding tcsL gene or the tcsH gene for TcsH. In addition, the strain was neither cytotoxic in vitro nor lethal in a murine...

2011-01-01

169

Microbiologic Evaluation of Patients from Missouri with Erythema Migrans  

UK PubMed Central (United Kingdom)

BackgroundBorrelia lonestari infects Amblyomma americanum, the tick species that is the most common cause of tick bites in southeast...Full Text Available

2005-02-01

170

Isoprinosine augmentation of phytohemagglutinin-induced lymphocyte proliferation.  

UK PubMed Central (United Kingdom)

The need for agents designed to modify immune response in the treatment of patients with viral infection, immunodeficiency, or cancer prompted the present study on the mechanisms of action of isoprinosine,...Full Text Available

1976-02-01

171

Intestinal parasitic infections and urbanization.  

UK PubMed Central (United Kingdom)

About a third of the population in the cities of developing countries live in slums and shanty towns. By the year 2000 it is estimated that this number will grow to 2200 million, and by 2025 about 57%...Full Text Available

1993-01-01

172

In Vitro Toxicity of Silver Nanoparticles in Human Lung ...  

Science.gov (United States)

... The MTT assay indicates cell viability through a yellow to purple ... besiegers were said to have catapulted plague infected corpses into the city of ...

2009-03-01

173

INJECTABLE IN SITU CROSS-LINKING HYDROGELS FOR LOCAL ANTIFUNGAL THERAPY  

UK PubMed Central (United Kingdom)

Invasive fungal infections can be devastating, particularly in immunocompromised patients, and difficult to treat with systemic drugs. Furthermore, systemic administration of those medications...Full Text Available

2010-02-01

174

Epidemiology, prevention and control of legionellosis: memorandum from a WHO meeting.  

UK PubMed Central (United Kingdom)

This Memorandum describes the following aspects of legionellosis: clinical presentations of legionella infection, general epidemiology (including nosocomial outbreaks and travel-associated legionnaires'...Full Text Available

1990-01-01

175

Current problems of perinatal Chlamydia trachomatis infections  

UK PubMed Central (United Kingdom)

Chlamydia trachomatis has been recognized as a pathogen of trachoma, nongonococcal urethritis, salpingitis, endocervicitis, pelvic inflammatory disease, inclusion conjunctivitis of...Full Text Available

176

Cowper's syringocele: an analysis of 15 consecutive cases.  

UK PubMed Central (United Kingdom)

Cystic dilatation of Cowper's gland ducts (Cowper's syringocele) is uncommon in children and is frequently asymptomatic, but it may cause urinary infection, haematuria, dysuria, and obstructive voiding...Full Text Available

1996-07-01

177

Clinical, virological and immunological responses in Danish HIV patients receiving raltegravir as part of a salvage regimen  

DEFF Research Database (Denmark)

Raltegravir is the first integrase inhibitor approved for treatment of HIV-infected patients harboring multiresistant viruses.

2010-01-01

178

Clinical significance of coagulase-negative staphylococci.  

UK PubMed Central (United Kingdom)

Although coagulase-negative staphylococci (C-NS) have been implicated in certain human infections, they are generally regarded as contaminants, and their clinical significance is questioned. To assess...Full Text Available

1982-08-01

179

Bacterial vaginosis and other asymptomatic vaginal infections in pregnancy.  

Science.gov (United States)

Preterm birth is a common cause of neonatal morbidity and mortality. Many asymptomatic genital infections have been associated with preterm birth, but attempts to determine a causal relationship between specific infections and preterm birth have been disappointing. Treatment trials of specific infections have generally failed to show a positive effect, and in some trials have shown a deleterious effect. Although there is a strong association between the presence of bacterial vaginosis and Trichomonas vaginalis in pregnancy and preterm birth, randomized treatment trials have failed to show a benefit of treatment of these organisms. Treatment of asymptomatic bacterial vaginosis or T. vaginalis to prevent preterm birth is not warranted. PMID:12112946

2001-08-01

180

Application of chloropicrin to Douglas-fir stumps to control laminated ...  

Science.gov (United States)

Sep 1, 2011 ... Title: Application of chloropicrin to Douglas-fir stumps to control laminated root rot does not affect infection or growth of regeneration 16 growing ...

182

A prospective randomised open label study to evaluate the potential of a new silver alginate/carboxymethylcellulose antimicrobial wound dressing to promote wound healing  

British Library Electronic Table of Contents (United Kingdom)

The aim of this study was to observe both the clinical signs and symptoms of wounds at risk of infection, that is critically colonised (biofilm infected) and antimicrobial-performance of an ionic silver alginate/carboxymethylcellulose (SACMC) dressing, in comparison with a non silver calcium alginate fibre (AF) dressing, on chronic venous leg and pressure ulcers. Thirty-six patients with venous or pressure ulcers, considered clinically to be critically colonised (biofilm infected), were randomly chosen to receive either an SACMC dressing or a non silver calcium AF dressing. The efficacy of each wound dressing was evaluated over a 4-week period. The primary study endpoints were prevention of infection and progression to wound healing. The SACMC group showed a statistically significant (P = ...

2010-01-01

183

A Novel Multi-Antigen Virally Vectored Vaccine against Mycobacterium avium Subspecies paratuberculosis  

UK PubMed Central (United Kingdom)

BackgroundMycobacterium avium subspecies paratuberculosis causes systemic infection and chronic intestinal inflammation in many species including...Full Text Available

184
186

Simple fractal method of assessment of histological images for application in medical diagnostics  

UK PubMed Central (United Kingdom)

We propose new method of assessment of histological images for medical diagnostics. 2-D image is preprocessed to form 1-D landscapes or 1-D signature of the image contour and then their complexity is...Full Text Available

187
194

Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy  

UK PubMed Central (United Kingdom)

In vivo two-photon imaging through the pupil of the primate eye has the potential to become a useful tool for functional imaging of the retina. Two-photon excited fluorescence images...Full Text Available

195

Image Engine: an object-oriented multimedia database for storing, retrieving and sharing medical images and text.  

UK PubMed Central (United Kingdom)

This paper describes Image Engine, an object-oriented, microcomputer-based, multimedia database designed to facilitate the storage and retrieval of digitized biomedical still images, video, and text...Full Text Available

1993-01-01

203

Adaptive Image Processing A Computational Intelligence Perspective  

CERN Document Server

Adaptive image processing is one of the most important techniques in visual information processing, especially in early vision such as image restoration, filtering, enhancement, and segmentation. This work focuses on applications of advanced CI techniques in image processing applications

2009-01-01

204

Real time neutron radiography using a Lixi neutron imaging device  

Energy Technology Data Exchange (ETDEWEB)

A real time neutron radiography system has been developed at the University of Michigan Phoenix Memorial Laboratory (PML) and has recently been used to test the imaging capabilities of a neutron imaging device developed by Lixi, Inc. of Downers Grove, Illinois. This device uses an input phosphor that is high in gadolinium to generate a light image which is then sent through an intensifier stage to provide images that can be viewed by eye, video camera, or standard 35 mm camera. It was determined that this device provides images of much higher resolution and sensitivity than those obtained with the imaging system currently being used at PML. Using computerized image enhancement techniques, the images obtained with the Lixi neutron imaging device can then be further enhanced or processed to obtain ...

1986-01-15

205

Real time neutron radiography using a Lixi neutron imaging device  

International Nuclear Information System (INIS)

A real time neutron radiography system has been developed at the University of Michigan Phoenix Memorial Laboratory (PML) and has recently been used to test the imaging capabilities of a neutron imaging device developed by Lixi, Inc. of Downers Grove, Ill. This device uses an input phosphor that is high in gadolinium to generate a light image which is then sent through an intensifier stage to provide images that can be viewed by eye, video camera, or standard 35 mm camera. It was determined that this device provides images of much higher resolution and sensitivity than those obtained with the imaging system currently being used at PML. Using computerized image enhancement techniques, the images obtained with the Lixi neutron imaging device can then be further enhanced or processed to obtain ...

1986-01-01

206

Advances in Modeling of Scanning Charged-Particle-Microscopy Images  

CERN Document Server

Modeling artificial scanning electron microscope (SEM) and scanning ion microscope images has recently become important. This is because of the need to provide repeatable images with a priori determined parameters. Modeled artificial images are highly useful in the evaluation of new imaging and metrological techniques, like image-sharpness calculation, or drift-corrected image composition (DCIC). Originally, the NIST-developed artificial image generator was designed only to produce the SEM images of gold-on-carbon resolution sample for image-sharpness evaluation. Since then, the new improved version of the software was written in C++ programming language and is in the Public Domain. The current version of the software can generate arbitrary samples, any drift function, and many other features. This ...

2010-01-01

207

Magnetic resonance imaging in childhood epilepsy  

International Nuclear Information System (INIS)

The suitability of MR imaging versus computerized tomography in observation of brain development disorders in children are compared. 13 refs.

208

Esters useful as brain imaging agents  

Energy Technology Data Exchange (ETDEWEB)

Certain radioiodine containing esters useful as brain imaging agents are disclosed. The formula of these compounds are presented.

1981-08-18

209

Esters useful as brain imaging agents  

International Nuclear Information System (INIS)

Certain radioiodine containing esters useful as brain imaging agents are disclosed. The formula of these compounds are presented.

210

Amides useful as brain imaging agents  

Energy Technology Data Exchange (ETDEWEB)

Certain radioiodine containing amides useful as brain imaging agents are disclosed. The compounds of the subject invention are represented by the formula

1981-07-21

211

Amides useful as brain imaging agents  

International Nuclear Information System (INIS)

Certain radioiodine containing amides useful as brain imaging agents are disclosed. The compounds of the subject invention are represented by the formula.

212

Image-enhancement applications at the Lawrence Livermore National Laboratory  

Energy Technology Data Exchange (ETDEWEB)

A diverse set of digital image-processing applications exists at the Lawrence Livermore National Laboratory. While many of these include some sort of image analysis or restoration, virtually all of them require image-enhancement procedures. In this paper we describe the principal image-processing facility at the Laboratory, followed by a discussion of several of the major image-processing application areas.

1982-06-01

213

The bovine immune response to Brucella abortus I. A water soluble antigen precipitated by sera of some naturally infected cattle.  

UK PubMed Central (United Kingdom)

Selected sera from cattle naturally infected with Brucella abortus precipitate water soluble antigens extracted by sonication from B. abortus. One of these antigens resembles antigen E (Baughn and Freeman)...Full Text Available

1977-04-01

214

Syncope as a probable side effect to combination antiretroviral therapy initiated during primary HIV-1 infection  

DEFF Research Database (Denmark)

A previously healthy young man experienced several episodes of syncope while being treated with tenofovir, emtricitabine and nevirapine initiated during primary HIV-1 infection. Symptoms disappeared after discontinuation of antiretroviral therapy and we suggest that syncope may be a side effect to one of the three antiretroviral drugs that has not been described previously.

2008-01-01

215

Ribose metabolism and nucleic acid synthesis in normal and glucose-6-phosphate dehydrogenase-deficient human erythrocytes infected with Plasmodium falciparum.  

UK PubMed Central (United Kingdom)

The metabolism of pentose-phosphate was investigated in Plasmodium falciparum-infected normal and glucose-6-phosphate dehydrogenase (G6PD)-deficient human red blood cells in vitro. 5'-Phosphoribosyl-1-pyrophosphate...Full Text Available

1986-04-01

216

Quantitation of transcribing native simian virus 40 minichromosomes extracted from CV1 cells late in infection.  

UK PubMed Central (United Kingdom)

Simian virus 40 transcriptional complexes could be extracted from CV1 cells late in infection and separated from the bulk of inactive viral chromatin. Sucrose gradient sedimentation, cesium sulfate...Full Text Available

1981-04-01

217

Primitive hematopoietic cells resist HIV-1 infection via p21Waf1/Cip1/Sdi1  

UK PubMed Central (United Kingdom)

Hematopoietic stem cells are resistant to HIV-1 infection. Here, we report a novel mechanism by which the cyclin-dependent kinase inhibitor (CKI) p21Waf1/Cip1/Sdi1 (p21), a known regulator...Full Text Available

2007-02-01

218

Practical approach to the loss of smell  

Energy Technology Data Exchange (ETDEWEB)

Loss of the sense of smell can be easily confirmed in any physician's office by having the patient try to identify various odors. The etiology of anosmia can be extremely varied, including nasopharyngeal disorders such as rhinitis and tumors; neurologic conditions such as head trauma, neoplasms, vascular lesions and infections of the central nervous system; viral infections; familial and congenital disorders; drugs; industrial exposure; endocrine diseases, and several other disorders. The prognosis of anosmia is guarded, and its treatment depends on the etiology.

1982-09-01

219

Lytic HSV-1 infection induces the multifunctional transcription factor Early Growth Response-1 (EGR-1) in rabbit corneal cells  

UK PubMed Central (United Kingdom)

BackgroundHerpes simplex virus type-1 (HSV-1) infections can cause a number of diseases ranging from simple cold sores to dangerous keratitis and lethal encephalitis. The interaction...Full Text Available

220

Live Brucella spp. fail to induce tumor necrosis factor alpha excretion upon infection of U937-derived phagocytes.  

UK PubMed Central (United Kingdom)

Tumor necrosis factor alpha (TNF-alpha) plays a central role in activation of first-line defenses of a host against foreign organisms. To determine whether Brucella infection modulated TNF-alpha production,...Full Text Available

1994-12-01

221

Intestinal helminths infection of rats (Ratus norvegicus) in the Belgrade area (Serbia): the effect of sex, age and habitat.  

Science.gov (United States)

SUMMARY: Gastrointestinal helminths of Norway rat (Rattus norvegicus) from the Belgrade area were studied as a part of a wider ecological research of rats in Serbia (data on the distribution, population ecology, economic and epizoothiological-epidemiological importance, and density control). Rats were captured from May 2005 to July 2009 at both urban and suburban-rural sites. Of a total of 302 trapped rats 48% were males and 52% females, with 36.5% and 38.8% of juvenile-subadult individuals, per sex respectively. Intestinal helminth infection was noted in 68.5% of rats, with a higher prevalence in male hosts and in adult individuals. Higher numbers of infected juveniles-subadults were noted in suburban-rural habitats, while an opposite tendency was noted in adult rats. Seven helminth species were recovered, of which five were nematode (Heterakis spumosa, Nippostrongylus brasiliensis, Capillaria sp., Trichuris muns and Syphacia muris) and two ...

2011-05-01

222

Interaction of ?V?3 and ?V?6 Integrins with Human Parechovirus 1?  

UK PubMed Central (United Kingdom)

Human parechovirus (HPEV) infections are very common in early childhood and can be severe in neonates. It has been shown that integrins are important for cellular infectivity of HPEV1 through experiments...Full Text Available

2010-09-01

223

Infection disclosure in the injecting dyads of Hungarian and Lithuanian injecting drug users who self-reported being infected with hepatitis C virus or human immunodeficiency virus.  

Science.gov (United States)

The aim of this study was to assess the prevalence and correlates of disclosure to network members of being hepatitis C virus (HCV)- or human immunodeficiency virus (HIV)-infected among injecting dyads of infected injection drug users (IDUs) in Budapest, Hungary and Vilnius, Lithuania,. Multivariate generalized estimating equations (GEE) were used to assess associations. Very strong infection disclosure norms exist in Hungary, and HCV disclosure was associated with using drugs and having sex within the dyad. Non-ethnic Russian IDUs in Lithuania were more likely to disclose HCV infection to non-Roma, emotionally close and HCV-infected network members, and to those with whom they shared cookers, filters, drug solutions or rinse water or got used syringes from, and if they had fewer non-IDU or IDU network members. Ethnic Russian Lithuanian IDUs were more likely to disclose HCV if they ...

2010-09-15

224

Indirect hemagglutination employing enterobacterial common antigen and Yersinia somatic antigen: a technique to differentiate brucellosis from infections involving cross-reacting Yersinia enterocolitica.  

UK PubMed Central (United Kingdom)

The existence of enterobacterial common antigen in Yersinia enterocolitica and its absence in Brucella abortus were utilized in an attempt to provide a method to distinguish Brucella infections from...Full Text Available

1980-02-01

225

Hypothyroidism in Noninterferon Treated-HCV Infected Individuals Is Associated with Abnormalities in the Regulation of Th17 Cells  

UK PubMed Central (United Kingdom)

HCV-Ag-specific TH17 cells secrete IL17, a cytokine involved in autoimmune diseases and regulated by IL10 and TGF-b. 5–12% of patients with chronic HCV infection have hypothyroidism. We evaluated...Full Text Available

2010-01-01

226

Evolutionary Constraints Acting on DDX3X Protein Potentially Interferes with Rev-Mediated Nuclear Export of HIV-1 RNA  

UK PubMed Central (United Kingdom)

Differential host-pathogen interactions direct viral replication in infected cells. In HIV-1 infected cells, nuclear export of viral RNA transcripts into cellular cytoplasm is governed by interaction...Full Text Available

227

Evolution of Hepatitis B Virus in a Chronic HBV-Infected Patient over 2 Years  

UK PubMed Central (United Kingdom)

Mutations in full-length HBV isolates obtained from a chronic HBV-infected patient were evaluated at three time points: 1 day, 6 months, and 31 months. While 5 nucleotides variation, and an 18 bp...Full Text Available

2011-01-01

228

Dissecting toxin immunity in virus-infected killer yeast uncovers an intrinsic strategy of self-protection  

UK PubMed Central (United Kingdom)

Toxin-secreting “killer” yeasts were initially identified >40 years ago in Saccharomyces cerevisiae strains infected with a double-stranded RNA “killer”...Full Text Available

2006-03-07

229

Detecting Sugarcane yellow leaf virus infection in asymptomatic leaves with hyperspectral remote sensing and associated leaf pigment analysis  

Science.gov (United States)

Sugarcane yellow leaf caused by Sugarcane yellow leaf virus (ScYLV) does not produce visual symptoms in most susceptible plants until late in the growing season. An experiment was conducted to determine if leaf reflectance and pigment analysis could be used to determine ScYLV infection prior to sym...

230

Dengue Plaque Reduction Neutralization Test (PRNT) in Primary and Secondary Dengue Virus Infections: How Alterations in Assay Conditions Impact Performance  

UK PubMed Central (United Kingdom)

Dengue virus (DENV) infection is a worsening global health problem. The plaque reduction neutralization test (PRNT) is currently considered to be the “gold standard” to characterize...Full Text Available

2009-11-01

231

Cerebral sparganosis. Case report.  

Science.gov (United States)

The tapeworm Spirometra mansonoides infects man worldwide, particularly in Asian countries. Rarely, the central nervous system is involved; such a case is presented here. In the total of 12 reported cases, including the case described, the worm presented clinically as a mass suspicious for neoplasm or chronic abscess cavity. Surgical removal was invariably curative in each case. Although infrequent, the possibility of tapeworm infection should be entertained in the evaluation of intracranial masses in patients who have visited exotic locales. PMID:2191089

1990-07-01

232

Association between Handling of Pet Treats and Infection with Salmonella enterica Serotype Newport Expressing the AmpC ?-Lactamase, CMY-2  

UK PubMed Central (United Kingdom)

Resistance to the extended-spectrum cephalosporins can occur in Salmonella species via the production of extended-spectrum and AmpC β-lactamases. We describe human infections...Full Text Available

2003-10-01

233

??+ T-Lymphocyte Cytotoxicity against Envelope-Expressing Target Cells Is Unique to the Alymphocytic State of Bovine Leukemia Virus Infection in the Natural Host  

UK PubMed Central (United Kingdom)

Bovine leukemia virus (BLV) is a complex B-lymphotrophic retrovirus of cattle and the causative agent of enzootic bovine leukosis. Serum antibody in infected animals does not correlate with protection...Full Text Available

2000-09-01

234

An Effective Method of Image Retrieval using Image Mining Techniques  

CERN Document Server

The present research scholars are having keen interest in doing their research activities in the area of Data mining all over the world. Especially, [13]Mining Image data is the one of the essential features in this present scenario since image data plays vital role in every aspect of the system such as business for marketing, hospital for surgery, engineering for construction, Web for publication and so on. The other area in the Image mining system is the Content-Based Image Retrieval (CBIR) which performs retrieval based on the similarity defined in terms of extracted features with more objectiveness. The drawback in CBIR is the features of the query image alone are considered. Hence, a new technique called Image retrieval based on optimum clusters is proposed for improving user interaction with image retrieval systems by fully exploiting ...

2010-01-01

235

Position of nuclear-medical techniques for evaluation of loosened total hip endroprostheses  

Energy Technology Data Exchange (ETDEWEB)

For diagnosis of loosening or infection after implantation of a single-side or double-side total hip endoprosthesis 59 patients being in pain were investigated by a combination of bone scan (Technetium-99m DPD) and leucocyte scan (Indium-111 labelled leucocytes). The correlation between clinical results and scintigraphic findings revealed: bone scintigraphy detects loosening of prostheses with 95% sensitivity (45/47); bone scintigraphy excludes an instable prosthesis with 89% specificity (3/27). 45% of the loosened prostheses revealed an infection (21/47): leucocyte scintigraphy could detect 17 correct positive. Three leucocyte scans of 53 prostheses without clinical signs of infection were false positive. Therefore, leucocyte scintigraphy had a sensitivity of 91% and a specificity of 94% for detecting infection. Bone scintigraphy can detect loosening of prostheses with 93% accuracy, Indium-111 labelled ...

1985-10-01

236

In vivo hypermutation of xenotropic murine leukemia virus-related virus DNA in peripheral blood mononuclear cells of rhesus macaque by APOBEC3 proteins.  

Science.gov (United States)

The gammaretrovirus, xenotropic murine leukemia virus-related virus (XMRV), replicates to high titers in some human cell lines and is able to infect non-human primates. To determine whether APOBEC3 (A3) proteins restrict XMRV infections in a non-human primate model, we sequenced proviral DNA from peripheral blood mononuclear cells of XMRV-infected rhesus macaques. Hypermutation characteristic of A3DE, A3F and A3G activities was observed in the XMRV proviral sequences in vivo. Furthermore, expression of rhesus A3DE, A3F, or A3G in human cells inhibited XMRV infection and caused hypermutation of XMRV DNA. These studies show that some rhesus A3 isoforms are highly effective against XMRV in the blood of a non-human primate model of infection and in cultured human cells. PMID:21982221

2011-10-01

237

Human T-cell lymphotropic virus type III infection of the central nervous system: a preliminary in situ analysis  

Energy Technology Data Exchange (ETDEWEB)

Patients with acquired immunodeficiency syndrome (AIDS) are subject to a spectrum of central nervous system (CNS) disorders. Recent evidence implicates the human T-cell lymphotropic virus type III (HTLV-III) in the pathogenesis of some of these illnesses, although the cells infected by the virus have yet to be identified. Using in situ hybridization, the authors examined brain tissue from two patients with AIDS encephalopathy for the presence of HTLV-III RNA. In both cases, viral RNA was detected and concentrated in, though not limited to, the white matter. The CNS cells most frequently infected included macrophages, pleomorphic microglia, and multinucleated giant cells. Less frequently, cells morphologically consistent with astrocytes, oligodendroglia, and rarely neurons were also infected. The findings strengthen the association of HTLV-III with the pathogenesis of AIDS encephalopathy. In situ hybridization can be applied ...

1986-11-07

238

A prospective randomised open label study to evaluate the potential of a new silver alginate/carboxymethylcellulose antimicrobial wound dressing to promote wound healing.  

Science.gov (United States)

The aim of this study was to observe both the clinical signs and symptoms of wounds at risk of infection, that is critically colonised (biofilm infected) and antimicrobial-performance of an ionic silver alginate/carboxymethylcellulose (SACMC) dressing, in comparison with a non silver calcium alginate fibre (AF) dressing, on chronic venous leg and pressure ulcers. Thirty-six patients with venous or pressure ulcers, considered clinically to be critically colonised (biofilm infected), were randomly chosen to receive either an SACMC dressing or a non silver calcium AF dressing. The efficacy of each wound dressing was evaluated over a 4-week period. The primary study endpoints were prevention of infection and progression to wound healing. The SACMC group showed a statistically significant (P = 0.017) improvement to healing as indicated by a reduction in the surface area of the wound, over the 4-week study ...

2010-05-31

239

In vivo and in vitro evaluation of dota-lanreotide radiolabelled with gallium-67  

International Nuclear Information System (INIS)

One of the refinements of modern Nuclear Medicine is the capacity of providing dynamic and kinetics images of the administered radiopharmaceutical, reproducing its transport mechanism, action sites, receptor binding and excretion route. With the continues technological advances new radiopharmaceuticals have been developed in order to express higher specificity and with higher characters of affinity between receptor/complex. One radiopharmaceutical is formed by a reagent or bio molecule that has in its structure a radioisotope, that has the objectives of carrying it to the organs of affinity or to benign or malign tumoral process. Somatostatin inhibits the growing and proliferation of several tumoral cells. Somatostatin analogs bind to somatostatic receptors that are expressed in different kind of neoplasia DOTA-LANREOTIDE (DOTALAN) is an octapeptide analog to somatostatin. The interest of labeling the bio conjugate with gallium-67 in Nuclear Medicine comes from its ...

240

High-resolution beta imaging; L'imagerie beta haute resolution  

Energy Technology Data Exchange (ETDEWEB)

For many years, {beta} radioactivity has been used to label molecules and follow them in various biological processes. {beta} imaging is obtained by autoradiography. Classically made on films or on photographic emulsions, autoradiography is now supplanted by radio-imagers which are very performing. The phosphor-imager, {beta}-imager and {mu}-imager are the systems mainly used today and their operating principles and properties are compared. The great advantages of these imagers are: their rapidity to obtain results and their reliability for absolute quantification. All emitters ({beta}{sup -}, {beta}{sup -} -{gamma} and {beta}{sup +}) are detectable as well as the gamma emitters of nuclear medicine, by means of their low energy electrons ejected during y emission. Phosphor-imager is well suited to energetic tracers and large series of ...

2007-04-15

241

CR portal imaging; A linac graphy using storage phosphor imaging systems  

Energy Technology Data Exchange (ETDEWEB)

In portal images with high energy X-ray (10 MV), it is sometimes difficult to verify the irradiation field because of the low contrast. Especially, in the abdominal and pelvic region, the deterioration of portal image quality is remarkable. To solve this problem, we took portal images using computed radiography (FCR). Also, we develop a technique in which a copper plate (3 mm) and lead foil (0.3 mm) are closely set in the front and rear of the photostimulable phosphor plate (imaging plate), for increased energy absorption. As a result, image quality was very high and we confirmed image improvement using observer performance experiments. We made a special cassette which can closely set metallic plates to imaging plate and load FCR-7000 directly. Therefore, image process becomes simple, and suitable for routine work. In ...

1992-07-01

242

Radioisotope imaging of brain tumors in two rhesus monkeys. Final report  

Energy Technology Data Exchange (ETDEWEB)

Two geriatic male rhesus monkeys were used for the radioisotope imaging in this research. Discussion of the radionuclide, materials, and method used to accomplish the neurologic examination and the results obtained, both during the procedure and confirmation of the results by necropsies were accompanied by color photos of scan images. Results were that the nuclear images provided accurate images of intracranial neoplasia.

1988-04-01

243

Impact of computers in radiography: the advent of digital radiography, part-2  

International Nuclear Information System (INIS)

Computed radiography (CR) systems use a photostimulable phosphor plate enclosed in a cassette. In CR, image acquisition is a two-stage process wherein image capture and image read out are done separately. Direct digital radiography (DR) systems, on the other hand, use detectors that have a combined image capture and image read out capability. DR systems are also called as DDR or ddR systems by some vendors. This article focuses on DR systems

2008-08-01

244

Fracture imaging with converted elastic waves  

Energy Technology Data Exchange (ETDEWEB)

This paper examines the seismic signatures of discrete, finite-length fractures, and outlines an approach for elastic, prestack reverse-time imaging of discrete fractures. The results of this study highlight the importance of incorporating fracture-generated P-S converted waves into the imaging method, and presents an alternate imaging condition that can be used in elastic reverse-time imaging when a direct wave is recorded (e.g., for crosswell and VSP acquisition geometries).

2001-05-29

245

Increased Prevalence of Albuminuria in HIV-Infected Adults with Diabetes  

Science.gov (United States)

ObjectiveHIV and type 2 diabetes are known risk factors for albuminuria, but no previous reports have characterized albuminuria in HIV-infected patients with diabetes.Research Design and MethodsWe performed a cross-sectional study including 73 HIV-infected adults with type 2 diabetes, 82 HIV-infected non-diabetics, and 61 diabetic control subjects without HIV. Serum creatinine >1.5 mg/dL was exclusionary. Albuminuria was defined as urinary albumin/creatinine ratio >30 mg/g.ResultsThe prevalence of albuminuria was significantly increased among HIV-infected diabetics (34% vs. 13% of HIV non-diabetic vs. 16% diabetic control, p?=?0.005). HIV status and diabetes remained significant predictors of albuminuria after adjusting for age, race, BMI, and blood pressure. Albumin/creatinine ratio correlated significantly with HIV viral load (r?=?0.28, p?=?0.0005) and HIV-infected subjects ...

2011-09-13

246

Targeted integration of baboon endogenous virus in the BEVI locus on human chromosome 6.  

Science.gov (United States)

The infection of cultured human cells with baboon endogenous virus (BEV) frequently leads to an association of viral DNA with a specific genetic locus (termed BEVI, for baboon endogenous virus infection) on chromosome 6. Restriction endonuclease digestion of DNA from BEV-infected human cells and their derived somatic cell clones frequently revealed a common cellular DNA sequence in the proximity of one of the junctions between cellular DNA and the integrated virus. We propose that a short cellular DNA sequence, repeated on chromosome 6 and separated by unique DNA sequences, presents a high-affinity target for the integration of BEV in human cells. PMID:6401843

1983-01-13

247

Susceptibility to invasive bacterial infections in children with sickle cell disease  

British Library Electronic Table of Contents (United Kingdom)

Individuals with sickle cell disease (SCD) demonstrate an increased susceptibility to invasive bacterial infections (IBI). The most common organisms causing IBI are Streptococcus pneumoniae, nontyphi Salmonella species and Haemophilus influenzae type b (Hib). IBI are the most common causes of death in children below 5 years of age with SCD. Increased susceptibility to IBI is because of several factors including dysfunctional antibody production and opsonophagocytosis as well as defective splenic clearance. Early diagnosis of Hib and pneumococcal infections combined with antibiotic prophylaxis and immunization programs, could lead to significant improvements in mortality, especially in Africa. Pediatr Blood Cancer. 2010;55:401-406. Copyright 2010 Wiley-Liss, Inc.

2010-01-01

248

Selective vulnerability of dorsal root ganglia neurons in experimental rabies after peripheral inoculation of CVS-11 in adult mice  

British Library Electronic Table of Contents (United Kingdom)

The involvement of dorsal root ganglia was studied in an in vivo model of experimental rabies virus infection using the challenge virus standard (CVS-11) strain. Dorsal root ganglia neurons infected with CVS in vitro show prolonged survival and few morphological changes, and are commonly used to study the infection. It has been established that after peripheral inoculation of mice with CVS the brain and spinal cord show relatively few neurodegenerative changes, but detailed studies of pathological changes in dorsal root ganglia have not previously been performed in this in vivo experimental model. In this study, adult ICR mice were inoculated in the right hindlimb footpad with CVS. Spinal cords and dorsal root ganglia were evaluated at serial time points for histopathological and ultrastru...

2009-01-01

249

Randomised, placebo-controlled trial to evaluate co-trimoxazole to reduce mortality and morbidity in HIV-infected post-natal women in Zambia (TOPAZ)  

British Library Electronic Table of Contents (United Kingdom)

Summary Objective- To evaluate the role of prophylactic trimethoprim-sulfamethoxazole (co-trimoxazole) antibacterial prophylaxis in reducing morbidity and mortality in HIV-infected post-natal women in southern Africa. Methods- Double-blind placebo-controlled trial. HIV-infected women with WHO stage 2 or 3 HIV disease who had recently delivered in the Department of Obstetrics and Gynaecology at the University Teaching Hospital, Lusaka, Zambia were randomised to receive daily co-trimoxazole (cotox) or matched placebo daily for the duration of the trial. Participants were followed up for a minimum of 1-year. Primary outcome measures were mortality from any cause or hospital admission and serious adverse events. Results- Of 600 women randomised, follow-up information was available from 355 (18...

2011-01-01

250

Prevalence and Incidence of HCV Infection among Vietnam Heroin Users with Recent Onset of Injection  

British Library Electronic Table of Contents (United Kingdom)

HCV infection continues to spread at an alarming rate among IDU populations. The available evidence suggests that HCV is acquired relatively quickly following onset of injection. However, there are few prospective studies of HCV acquisition, particularly among IDU populations in resource-poor settings. A sample of young male heroin injectors with recent onset of injection (<4?years) was recruited in Hanoi, Vietnam for a prospective assessment of the early course of injection (n?=?179). Both behavioral and biological assessments (including detailed retrospective assessment of injection initiation) were conducted at baseline and repeated at 6-month intervals for a period of 16?months. Variables associated with HCV infection (p value?p value?=?0.0005). In multivariate logistic regression anal...

2010-01-01

251

Outcome of peripherally inserted central venous catheters in surgical and medical neonates  

British Library Electronic Table of Contents (United Kingdom)

Background/Purpose: Peripherally inserted central venous catheters (PICCs) are commonly used for neonatal vascular access. The aim of this study was to look at PICC line complication rates and possible predictors of PICC infection in a neonatal intensive care unit. Method: This was a prospective study of 226 neonates who had PICCs on our neonatal intensive care unit between January 2006 and June 2009. Complete data was available on 218 neonates who had 294 PICC lines. Criteria for catheter-related sepsis was positive blood cultures (peripheral/central) and/or a positive catheter tip culture after removal in the presence of a clinical suspicion of line sepsis. Results: Of 218 neonates, 132 (169 lines) were medical, and 86 (125 lines) were surgical. Our PICC line infection rate was 17 infect...

2011-01-01

252

Epidemic spreading with nonlinear infectivity in weighted scale-free networks  

CERN Document Server

In this paper, we investigate the epidemic spreading for SIR model in weighted scale-free networks with nonlinear infectivity, where the transmission rate in our analytical model is weighted. Concretely, we introduce the infectivity exponent $\\alpha$ and the weight exponent $\\beta$ into the analytical SIR model, then examine the combination effects of $\\alpha$ and $\\beta$ on the epidemic threshold and phase transition. We show that one can adjust the values of $\\alpha$ and $\\beta$ to rebuild the epidemic threshold to a finite value, and it is observed that the steady epidemic prevalence $R$ grows in an exponential form in the early stage, then follows hierarchical dynamics. Furthermore, we find $\\alpha$ is more sensitive than $\\beta$ in the transformation of the epidemic threshold and epidemic prevalence, which might deliver some useful information or new insights in the epidemic spreading and the correlative immunization schemes.

2009-01-01

253

Effect of host nutrition on immunity and local immune response of rabbits to Obeliscoides cuniculi  

International Nuclear Information System (INIS)

In a series of experiments carried out on young and adult rabbits the effect of isocaloric low protein diets containing 4% or 8% protein compared with a diet containing 21% protein on Obeliscoides cuniculi infection was studied. The pathogenesis, resistance and local immunity were assessed after single infections with 10,000 larvae or reinfection with 5000 larvae. Live weight gain was reduced in young and adult rabbits fed the low protein diets, but the establishment of parasites was not substantially influenced by protein deprivation. However, development of worms in the histotrophic phase and parasite fecundity were impaired in association with the low protein diet. Moreover, mild anaemia as well as changes in the mucosal immune response as a result of infection were related to the level of dietary protein. (author). 30 refs, 6 figs, 5 tabs.

1987-05-11

254

Changing Treatment Paradigms Hepatitis C Virus in HIV-Infected Patients  

British Library Electronic Table of Contents (United Kingdom)

The evaluation of hepatic histology and treatment of hepatitis C virus (HCV)/HIV-coinfected patients is rapidly changing. HCV has become an important cause of mortality in HIV-infected patients. Consequently, assessment of liver histology in all coinfected patients is particularly important. The evaluation of hepatic histology is shifting from reliance on the liver biopsy toward noninvasive modalities. Additionally, the importance of HCV-associated morbidity and mortality in HIV-infected patients has prompted increasing numbers of these patients to be HCV treatment candidates. Prospective trials in coinfected patients have reported lower sustained virologic responses compared to HCV-monoinfected patients. Consequently, the numbers of coinfected nonresponders to pegylated interferon/ribavir...

2007-01-01

255

Benign lymphoepithelial lesion of the parotid gland in AIDS patients: CT characteristics  

International Nuclear Information System (INIS)

Contrast agent-enhanced CT scans in nine male patients with histologically proved benign lymphoepithelial lesions of the perotid gland were reviewed. All scans showed cystic-appearing masses with peripheral rim enhancement corresponding to the macroscopic appearance of the lesion. Five patients were seropositive for human immunodeficiency virus (HIV) infection or had infections seen in acquired immunodeficiency syndrome. Three patients were members of high-risk groups. Only one patient had symptoms of the SICCA syndrome. Once a rare cause of parotid gland enlargement, benign lymphoepithelial lesions have recently been seen with increasing frequency in patients with HIV infection. Although the CT appearance is not pathognomic, correlation results of aspiration cytology and with clinical history can lead to a preoperative diagnosis of a benign lymphoepithelial lesion.

256

Real-time neutron coded aperture imaging: A technique for nondestructive three-dimensional imaging  

Energy Technology Data Exchange (ETDEWEB)

Neutron Coded Aperture Imaging is a nondestructive imaging technique that utilizes neutrons scattered from an object through specially designed apertures. Coded Aperture Imaging is an alternative technique to Computed Tomography for three-dimensional imaging. Coded Aperture Imaging has the advantage that all of the three-dimensional information is contained in a single image, whereas Computed Tomography requires several images or projections. This technique has been implemented by other using photographic film as an image recording medium and optical reconstruction or decoding of the images. In this work, the possibility of using a real-time neutron video camera to record the images, followed by digital decoding methodology has been investigated. Because only a small fraction of ...

1992-01-01

257

The Possibility of Digital Imaging in the Diagnosis of Occlusal Caries  

UK PubMed Central (United Kingdom)

The aim of this study was to assess the possibility of digital image analysis of pit-and-fissure discoloration in order to diagnose caries. Digital images showing pit-and-fissure discoloration in 100...Full Text Available

2010-01-01

258

Selective imaging of adherent targeted ultrasound contrast agents  

UK PubMed Central (United Kingdom)

The goal of ultrasonic molecular imaging is the detection of targeted contrast agents bound to receptors on endothelial cells. We propose imaging methods that can distinguish adherent microbubbles...Full Text Available

2007-04-21

259

Radionuclide imaging of the acutely painful scrotum  

International Nuclear Information System (INIS)

This paper discusses the clinical application and main objective of testicular imaging. The authors present cases that represent a spectrum of the abnormalities which might be detected by testicular imaging, with special attention given to testicular torsion and the acute diseases which may mimic it clinically. Accuracy of the test is noted.

260

Quantifying the accuracy of automated structure segmentation in 4D CT images using a deformable image registration algorithm  

UK PubMed Central (United Kingdom)

Four-dimensional (4D) radiotherapy is the explicit inclusion of the temporal changes in anatomy during the imaging, planning, and delivery of radiotherapy. One key component of 4D radiotherapy planning...Full Text Available

2008-04-01

261

Performance evaluation of an automatic anatomy segmentation algorithm on repeat or four-dimensional CT images using a deformable image registration method  

UK PubMed Central (United Kingdom)

PurposeAuto-propagation of anatomical region-of-interests (ROIs) from the planning CT to daily CT is an essential step in image-guided adaptive radiotherapy. The...Full Text Available

2008-09-01

262

Nonnegative Factorization of Diffusion Tensor Images and Its Applications  

UK PubMed Central (United Kingdom)

This paper proposes a novel method for computing linear basis images from tensor-valued image data. As a generalization of the nonnegative matrix factorization, the proposed method aims to approximate...Full Text Available

2011-01-01

263

Near Infrared-Fluorescent and Magnetic Resonance Imaging Molecular Probe with High T1 Relaxivity for In Vivo Multimodal Imaging  

UK PubMed Central (United Kingdom)

A new gadolinium chelating NIR fluorescent molecular probe increases T1 relaxivity of water protons, facilitating combined optical and magnetic resonance imaging.

2010-06-07

264

MULTIMODALITY IMAGING: BEYOND PET/CT AND SPECT/CT  

UK PubMed Central (United Kingdom)

Multimodality imaging with PET/CT and SPECT/CT has become commonplace in clinical practice and in preclinical and basic medical research. Do other combinations of imaging modalities have a similar...Full Text Available

2009-09-01

265

Longitudinal assessment of lung cancer progression in the mouse using in vivo micro-CT imaging  

UK PubMed Central (United Kingdom)

Purpose: Small animal micro-CT imaging is being used increasingly in preclinical biomedical research to provide phenotypic descriptions of genomic models. Most of this imaging is coincident...Full Text Available

2010-09-01

266

Imaging of calcium transients in skeletal muscle fibers.  

UK PubMed Central (United Kingdom)

Epifluorescence images of Ca2+ transients elicited by electrical stimulation of single skeletal muscle fibers were studied with fast imaging techniques that take advantage of the large fluorescence...Full Text Available

1991-01-01

267

High speed optical coherence microscopy with autofocus adjustment and a miniaturized endoscopic imaging probe  

UK PubMed Central (United Kingdom)

Optical coherence microscopy (OCM) is a promising technique or high resolution cellular imaging in human tissues. An OCM system for high-speed en face cellular resolution imaging...Full Text Available

2010-03-01

268

Diagnostic radiology: An Anglo-American textbook of imaging  

Energy Technology Data Exchange (ETDEWEB)

This multiauthored text is aimed particularly toward the resident or registrar training in diagnostic radiology. This is a text book on the entire scope of diagnostic imaging. It includes techniques and imaging modalities of all the systems, head, face and neck. The book covers the entire gamut of diagnostic radiology.

1986-01-01

269

Diagnostic quality of low resolution images for tele-woundcare.  

UK PubMed Central (United Kingdom)

The use of digital wound images would allow remote consultation between patients, physicians, or other caregivers over the Internet. To evaluate the efficacy and validity of digital images for assessment...Full Text Available

1998-01-01

270

Comprehensive Quantification of Signal-to-Noise Ratio and g-Factor for Image-Based and k-Space-Based Parallel Imaging Reconstructions  

UK PubMed Central (United Kingdom)

Parallel imaging reconstructions result in spatially varying noise amplification characterized by the g-factor, precluding conventional measurements of noise from the final...Full Text Available

2008-10-01

271

Comparative evaluation of similarity measures for the rigid registration of multi-modal head images  

Energy Technology Data Exchange (ETDEWEB)

Image registrations that are based on similarity measures simply adjust the parameters of an appropriate spatial transformation model until the similarity measure reaches an optimum. The numerous similarity measures that have been proposed in the past are differently sensitive to imaging modality, image content and differences in the image content, selection of the floating and target image, partial image overlap, etc. In this paper, we evaluate and compare 12 similarity measures for the rigid registration. To study the impact of different imaging modalities on the behavior of similarity measures, we have used 16 CT/MR and 6 PET/MR image pairs with known 'gold standard' registrations. The results for the PET/MR registration and for the registration of CT to both rectified and unrectified MR ...

2007-09-21

272

Compact Image Slicing Spectrometer (ISS) for hyperspectral fluorescence microscopy  

UK PubMed Central (United Kingdom)

An image slicing spectrometer (ISS) for microscopy applications is presented. Its principle is based on the redirecting of image zones by specially organized thin mirrors within a custom fabricated...Full Text Available

2009-07-20

273

CR portal imaging  

International Nuclear Information System (INIS)

In portal images with high energy X-ray (10 MV), it is sometimes difficult to verify the irradiation field because of the low contrast. Especially, in the abdominal and pelvic region, the deterioration of portal image quality is remarkable. To solve this problem, we took portal images using computed radiography (FCR). Also, we develop a technique in which a copper plate (3 mm) and lead foil (0.3 mm) are closely set in the front and rear of the photostimulable phosphor plate (imaging plate), for increased energy absorption. As a result, image quality was very high and we confirmed image improvement using observer performance experiments. We made a special cassette which can closely set metallic plates to imaging plate and load FCR-7000 directly. Therefore, image process becomes simple, and suitable for routine work. In ...

1992-01-01

274

An Evaluation of a Computer Imaging Program to Prepare Women for Chemotherapy-related Alopecia  

UK PubMed Central (United Kingdom)

ObjectiveThis study was conducted to evaluate a computer-imaging program called HAAIR (Help with Adjustment to Alopecia by Image Recovery) that was developed to provide...Full Text Available

2010-07-01

275

A BPF-FBP tandem algorithm for image reconstruction in reverse helical cone-beam CT  

UK PubMed Central (United Kingdom)

Purpose: Reverse helical cone-beam computed tomography (CBCT) is a scanning configuration for potential applications in image-guided radiation therapy in which an accurate anatomic image...Full Text Available

2010-01-01

276

Post-mortem fetal MRI: What do we learn from it?  

International Nuclear Information System (INIS)

Post-mortem magnetic resonance (MR) imaging is of increasing interest not only as an alternative to autopsy but as a research tool to aid the interpretation and diagnosis of in utero MR images. The information from the post-mortem MR has allowed the development of imaging sequences applicable to in utero imaging and neonatal imaging. It has established brain development during gestation and has provided data on this to which in utero MR can be compared. The detail available from the post-mortem images is such that brain development can be studied in a non-invasive manner, a permanent record on the normal and abnormal areas is available and a greater understanding of developmental abnormalities is possible.

2006-02-01

277

MR imaging in neuroborreliosis of the cervical spinal cord  

Energy Technology Data Exchange (ETDEWEB)

The central nervous system is involved in 10-20% of cases in Lyme disease. The neurological symptoms, time course of the disease and imaging findings are multifaceted. We report two patients with cervical radiculitis. Magnetic resonance imaging revealed strong enhancement of the cervical nerve roots on contrast-enhanced T1-weighted images. These imaging patterns of borrelia-associated radiculitis have not been reported before. Knowledge of these imaging features may help to diagnose neuroborreliosis, which presents with non-specific symptoms. (orig.)

2004-11-01

278

Future of X-ray phase imaging in medical imaging technology  

International Nuclear Information System (INIS)

Weakly absorbing materials, such as biological, soft tissues, can be imaged by generating contrast due to the phase shift of X-rays. In the past decade, several methods for X-ray phase imaging were proposed and demonstrated. The performance of X-ray phase imaging is attractive in the field of medical imaging technology, and its development for practical use is expected. Many methods, however, have been developed under the assumption of the use of synchrotron radiation, which is an obstacle to practical use. The method based on Talbot (-Lau) interferometry enables us to use a compact X-ray source, and its development is expected as a breakthrough for medical applications. (author)

2007-04-01

279

Typhoon Aere : Image of the Day - NASA Earth Observatory  

Science.gov (United States)

Aug 25, 2004 ... The Tropical Rainfall Measuring Mission or TRMM satellite provided this image of Typhoon Aere over the western Philippine Sea as it was ...

280

The importance of radiation quality for optimisation in radiology  

UK PubMed Central (United Kingdom)

Selection of the appropriate radiation quality is an important aspect of optimisation for every clinical imaging task in radiology, since it affects both image quality and patient dose. Spreadsheet...Full Text Available

281

The Use of Medical Images in Planning and Delivery of Radiation Therapy  

UK PubMed Central (United Kingdom)

Abstract The authors provide a survey of how images are used in radiation therapy to improve the precision of radiation therapy plans, and delivery of radiation treatment. In contrast...Full Text Available

1997-09-01

282

Portal localization images using computed radiography for high-energy electron beam therapy  

Energy Technology Data Exchange (ETDEWEB)

Portal localization images for high-energy electron beam therapy are necessary to confirm the treatment field by comparing them with a simulation image obtained before treatment or portal verification images after treatment. In this study, portal localization images were acquired using the computed radiography (CR) system and bremsstrahlung X-rays generated in the electron beam irradiations. All images obtained with phantom and the irradiations of in the electron energy of 8, 10, 12 and 15 MeV were feasible for clinical use. The CR system used in this study included general diagnostic imaging cassette and storage phosphor plate, but none of other special devices. The system can usually supply portal localization images, which maintains the quality assurance of high-energy electron beam therapy. (author)

2002-09-01

283

Method for the reduction of image content redundancy in large image databases  

Energy Technology Data Exchange (ETDEWEB)

A method of increasing information content for content-based image retrieval (CBIR) systems includes the steps of providing a CBIR database, the database having an index for a plurality of stored digital images using a plurality of feature vectors, the feature vectors corresponding to distinct descriptive characteristics of the images. A visual similarity parameter value is calculated based on a degree of visual similarity between features vectors of an incoming image being considered for entry into the database and feature vectors associated with a most similar of the stored images. Based on said visual similarity parameter value it is determined whether to store or how long to store the feature vectors associated with the incoming image in the database.

2010-03-02

284

JHK and 3.3um PAH Imaging of the Starburst Ring in the Type I Seyfert Galaxy NGC 7469  

Science.gov (United States)

Imaging of NGC 7469 in the J, H, & K bands shows that the starburst 'ring' is a tight inner

1993-01-01

285

Implementation of improved interactive image analysis at the Advanced Photon Source (APC) linac.  

Energy Technology Data Exchange (ETDEWEB)

An image-analysis system, based on commercially available data visualization software (IDL [1]), allows convenient interaction with image data while still providing calculated beam parameters at a rate of up to 2 Hz. Image data are transferred from the IOC to the workstation via EPICS [2] channel access. A custom EPICS record was created in order to overcome the channel access limit of 16k bytes per array. The user can conveniently calibrate optical transition radiation (OTR) and fluorescent screens, capture background images, acquire and average a series of images, and specify several other filtering and viewing options. The images can be saved in either IDL format or APS-standard format (SDDS [3]), allowing for rapid postprocessing of image data by numerous other software tools.

1998-09-11

286

Imaging subsurface using cross-correlation  

Energy Technology Data Exchange (ETDEWEB)

This paper presents two imaging methods by using cross correlation. The one method images the subsurface by cross-correlation of the observed data and partial derivative seismograms calculated for a guessed model. The other method images the interface by use of cross-correlation of the virtual sources and the back propagated wave fields calculated from the observed data. Experimental tests show that both methods image subsurface interfaces well even if the guessed model is different from the true one. These imaging methods are reverse time migration that we perform cross-correlation as an imaging condition and have an advantage, as compared to conventional waveform inversion method, that images subsurface structure without iterative perturbation of the assumed model. (author). 18 refs., 15 figs.

1997-12-31

287

Image Analysis and Computer Vision: 1996.  

Science.gov (United States)

... Title : Image Analysis and Computer Vision: 1996. ... bibliography,. Corporate Author : MARYLAND UNIV COLLEGE PARK COMPUTER VISION LAB. ...

1997-01-01

288

Histopathological Image Analysis: A Review  

UK PubMed Central (United Kingdom)

Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches...Full Text Available

2009-01-01

289

AIDS and lung infection by Mycobacterium xenopi. Role of Computed Tomography; Sindrome da immunodeficienza acquisita e malattie polmonari da Mycobacterium xenopi. Ruolo della Tomografia Computerizzata  

Energy Technology Data Exchange (ETDEWEB)

Mycobacterium xenopi is one of the most common agents responsible for nontubercolar mycobacterial pulmonary disease on AIDS patients. These lesions have been studied with conventional radiography while CT has been used in patients with aspecific mycobacterioses or non-AIDS pulmonary conditions from Mycobacterium xenopi. 12 AIDS patients were examined. They had pulmonary lesions from Mycobacterium xenopi, patients age ranged 30 to 46 years. All patients had CD4 blood levels lower than 250 cells/mL and Mycobacterium xenopi in the sputum. All patients underwent a standard chest radiograph and a CT examination. CT images were evaluated by three radiologists independently and the definitive diagnosis was made in the presence of a fourth radiologist. Chest CT showed parenchymal consolidation in 66% of cases, associated with bilateral basal bands in 16% of cases. Consolidation was unilateral in 41% of cases and most frequently involved the right lower lobe. Bilateral ...

2000-06-01

290

Zoonoses-With Friends Like This, Who Needs Enemies?  

UK PubMed Central (United Kingdom)

Zoonoses are infections that are spread from animals to humans. Most often, humans are “dead-end” hosts, meaning that there is no subsequent human-to-human transmission. If one considers...Full Text Available

2008-01-01

291

Variant influenza virus hemagglutinin that induces fusion at elevated pH.  

UK PubMed Central (United Kingdom)

The hemagglutinin (HA) glycoprotein of influenza virus performs two critical roles during infection: it binds virus to cell surface sialic acids, and under mildly acidic conditions it induces fusion...Full Text Available

1986-02-01

292

Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans  

UK PubMed Central (United Kingdom)

Bloodstream infection by highly antibiotic-resistant bacteria, such as vancomycin-resistant Enterococcus (VRE), is a growing clinical problem that increasingly defies medical intervention....Full Text Available

2010-12-01

293

Value of individual household water supplies in the maintenance phase of a schistosomiasis control programme in Saint Lucia, after chemotherapy*  

UK PubMed Central (United Kingdom)

Between 1970 and 1975, the incidence of new Schistosoma mansoni infections was reduced in 5 villages after each household was provided with its individual water supply and community...Full Text Available

1982-01-01

294

Validation of Cultivation and PCR Methods for Diagnosis of Lyme Neuroborreliosis?  

UK PubMed Central (United Kingdom)

Borrelial infection may manifest with a wide range of clinical signs, and in many cases, microbiological findings are essential for a proper diagnosis. This study included 48 patients with a working...Full Text Available

2008-10-01

295

Urinary tract infection in children.  

UK PubMed Central (United Kingdom)

During 1968-77, 572 consecutive children with one or more positive urine cultures who were referred by their family doctors to one paediatric surgical outpatient clinic were investigated and prospectively...Full Text Available

1984-08-04

296

Urethral syndrome in women attending a clinic for sexually transmitted diseases.  

UK PubMed Central (United Kingdom)

Of 107 women investigated for frequency of micturition and dysuria, 21 had gonorrhoea, 14 chlamydial urethritis, eight an Escherichia coli urinary tract infection, 18 candidosis, 12 trichomoniasis,...Full Text Available

1983-06-01

297

Transmission of Salmonella mbandaka to cattle from contaminated feed.  

UK PubMed Central (United Kingdom)

Salmonella mbandaka was isolated from cattle on three dairy farms. The duration of infection was less than four weeks and none of the animals became clinically ill. The animals had all consumed a diet...Full Text Available

1982-04-01

298

Transcriptional mapping of the 3' end of the bovine syncytial virus genome.  

UK PubMed Central (United Kingdom)

The bovine syncytial virus, a member of the retroviral subfamily Spumavirinae, causes a persistent, asymptomatic infection in cattle. Nucleotide sequence analysis of the viral genome revealed two overlapping...Full Text Available

1994-02-01

299

Tinea nigra by Hortaea werneckii, a report of 22 cases from Mexico  

UK PubMed Central (United Kingdom)

Tinea nigra is a superficial mycosis caused by Hortaea werneckii. It is an infrequent asymptomatic infection that affects human palms and soles, and is mostly observed in tropical...Full Text Available

2008-01-01

300

Tick-Borne Relapsing Fever in British Columbia, Canada: First Isolation of Borrelia hermsii  

UK PubMed Central (United Kingdom)

The spirochete that causes tick-borne relapsing fever, Borrelia hermsii, was isolated in pure culture during 1995 and 1996 from three acutely ill human patients infected in southern...Full Text Available

1998-12-01

301

The relationships of salmonellae from infected broiler flocks, transport crates or processing plants to contamination of eviscerated carcases.  

UK PubMed Central (United Kingdom)

Three flocks raised for broiler or roaster performance tests were studied to determine the incidence and sources of salmonellae during the growing period, transport and processing and to relate these...Full Text Available

1982-07-01

302

The protozoan parasite Theileria annulata alters the differentiation state of the infected macrophage and suppresses musculoaponeurotic fibrosarcoma oncogene (MAF) transcription factors  

UK PubMed Central (United Kingdom)

AbstractThe tick-borne protozoan parasite Theileria annulata causes a debilitating disease of cattle called Tropical Theileriosis. The parasite predominantly invades...Full Text Available

2009-08-01

303

The Influence of Abacavir and Other Antiretroviral Agents on Virologic Response to Hepatitis C Virus Therapy Among Antiretroviral-Treated HIV-Infected Patients  

UK PubMed Central (United Kingdom)

BackgroundIt remains unclear if certain antiretroviral medications, particularly abacavir, compromise response to hepatitis C virus (HCV) therapy. Such data can inform...Full Text Available

2010-01-01

304

The Case for Selection at CCR5-?32  

UK PubMed Central (United Kingdom)

The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Δ32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested...Full Text Available

2005-11-01

305

The Blind NasoTracheal Aspiration Method Is Not a Useful Tool for Pathogen Detection of Pneumonia in Children  

UK PubMed Central (United Kingdom)

BackgroundAcute lower respiratory infection (ALRI) is a major cause of hospitalization for children in China, while the etiological diagnosis of ALRI remains a challenge. This study...Full Text Available

306

Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs  

UK PubMed Central (United Kingdom)

BackgroundTrypanosoma cruzi, the etiologic agent of Chagas Disease, is a major vector borne health problem in Latin America and an emerging...Full Text Available

307

Temporal Correlations between Tick Abundance and Prevalence of Ticks Infected with Borrelia burgdorferi and Increasing Incidence of Lyme Disease  

UK PubMed Central (United Kingdom)

The abundance of host-seeking Ixodes scapularis nymphs, the principal vector for the Lyme disease agent, Borrelia burgdorferi, in Old Lyme, Lyme, and East Haddam, Connecticut,...Full Text Available

1998-05-01

308

Survival of HIV-Infected Adolescents on Antiretroviral Therapy in Uganda: Findings from a Nationally Representative Cohort in Uganda  

UK PubMed Central (United Kingdom)

BackgroundAdolescents have been identified as a high-risk group for poor adherence to and defaulting from combination antiretroviral therapy (cART) care. However, data on outcomes...Full Text Available

309

Sugarcane Rust Inoculations  

Science.gov (United States)

Sugarcane rusts, brown (caused by Puccinia melanocephala) and orange (caused by P. kuehnii), are agronomically important diseases in Florida. Cultivar resistance is the best means of managing these diseases. Unfortunately, natural infection of brown rust is not always efficient in determining resist...

310

Sternal plate fixation for sternal wound reconstruction: initial experience (Retrospective study)  

UK PubMed Central (United Kingdom)

BackgroundMedian sternotomy infection and bony nonunion are two commonly described complications which occur in 0.4 - 5.1% of cardiac procedures. Although relatively infrequent,...Full Text Available

311

Spatial Re-Establishment Dynamics of Local Populations of Vectors of Chagas Disease  

UK PubMed Central (United Kingdom)

BackgroundPrevention of Chagas disease depends mainly on control of the insect vectors that transmit infection. Unfortunately, the vectors have been resurgent in some areas. It is...Full Text Available

312

Sparganosis in the Lumbar Spine : Report of Two Cases and Review of the Literature  

UK PubMed Central (United Kingdom)

Sparganosis is a rare parasitic infection affecting various organs, including the central nervous system, especially the lumbar epidural space. This report describes the identification of disease and...Full Text Available

2011-04-01

313

Some characteristics of a secreted chlamydial antigen recognized by IgG from C. trachomatis patient sera.  

UK PubMed Central (United Kingdom)

Chlamydia trachomatis serovars release a glycolipid antigen (GLXA) into the culture supernatant during the infective cycle. This antigen is recognized by IgG isolated from humans with a natural chlamydial...Full Text Available

1989-12-01

314

Significant asymptomatic bacteriuria among Nigerian type 2 diabetics.  

UK PubMed Central (United Kingdom)

Significant asymptomatic bacteriuria is a risk factor for symptomatic urinary infection and septicemia among predisposed individuals such as diabetics. We investigated the pattern of asymptomatic bacteriuria...Full Text Available

2003-05-01

315

Serratia odorifera biogroup 1 causing an invasive human infection.  

UK PubMed Central (United Kingdom)

Serratia odorifera biogroup 1 was isolated from the blood and urine of an alcoholic male with cirrhosis and signs of septic shock. The organism is rarely reported to occur in clinical specimens. This...Full Text Available

1988-06-01

316

Seroprevalence of HIV-1 and HIV-2 infection among children diagnosed with protein-calorie malnutrition in Nigeria.  

UK PubMed Central (United Kingdom)

Excessive weight loss due to protein calorie malnutrition (PCM) is a significant problem in Nigerian children. This syndrome may be difficult to differentiate from the wasting disease caused by human...Full Text Available

1993-04-01

317

Selective Degradation of Newly Synthesized Nonmessenger Simian Virus 40 Transcripts  

UK PubMed Central (United Kingdom)

By pretreating simian virus 40-infected BSC-1 cells with glucosamine, [3H]uridine labeling of both cellular and viral RNA can be halted instantaneously by addition of cold uridine. We have...Full Text Available

1978-11-01

318

Scaling up prevention programmes to reduce the sexual transmission of HIV in China  

UK PubMed Central (United Kingdom)

Background Since 2007, sex has been the major mode of HIV transmission in China, accounting for 75% of new infections in 2009. Reducing sexual transmission is a major challenge for China...Full Text Available

2010-12-01

319

Roxithromycin compared with erythromycin against genitourinary chlamydial infections.  

UK PubMed Central (United Kingdom)

The efficacy and safety of roxithromycin 300 mg once a day was compared with that of erythromycin 500 mg twice a day, both for seven days, in a double blind study of 281 patients (188 men, 93 women)...Full Text Available

1989-01-01

320

Role of Group A Streptococcal Virulence Factors in Adherence to Keratinocytes  

UK PubMed Central (United Kingdom)

To evaluate the role of putative group A streptococcal virulence factors in the initiation of skin infections, we compared the adherence of a wild-type M49-protein skin-associated strain to that of...Full Text Available

2000-03-01

321

Rifampin pharmacokinetics in children, with and without human immunodeficiency virus infection, hospitalized for the management of severe forms of tuberculosis  

UK PubMed Central (United Kingdom)

BackgroundRifampin is a key drug in antituberculosis chemotherapy because it rapidly kills the majority of bacilli in tuberculosis lesions, prevents relapse and thus enables 6-month...Full Text Available

322

Regulation of DAF-16-mediated Innate Immunity in Caenorhabditis elegans*  

UK PubMed Central (United Kingdom)

Activation of the innate immune system results in a rapid microbicidal response against microorganisms, which needs to be fine-tuned because uncontrolled immune responses can lead to infection and cancer,...Full Text Available

2009-12-18

323

Recurrent miscarriage and variant alleles of mannose binding lectin, tumour necrosis factor and lymphotoxin ? genes  

UK PubMed Central (United Kingdom)

Variant alleles of the mannose binding lectin (MBL) gene are associated with increased susceptibility to infection and polymorphisms of tumour necrosis factor and lymphotoxin alpha genes (TNF, LTA)...Full Text Available

2001-12-01

324

Recent changes in the epidemiology and management of extended-spectrum ?-lactamase-producing Enterobacteriaceae  

UK PubMed Central (United Kingdom)

Since 2000, Escherichia coli producing CTX-M enzymes (especially CTX-M-15) have emerged worldwide as important causes of community-onset urinary tract and blood stream infections due...Full Text Available

325

Rapid, sensitive detection of Mycoplasma pneumoniae in simulated clinical specimens by DNA amplification.  

UK PubMed Central (United Kingdom)

The polymerase chain reaction (PCR) was investigated as a means of diagnosing Mycoplasma pneumoniae infections. The target DNA sequence was a 375-bp segment of the P1 virulence protein. This DNA segment...Full Text Available

1992-12-01

326

Randomized placebo-controlled trial on azithromycin to reduce the morbidity of bronchiolitis in Indigenous Australian infants: rationale and protocol  

UK PubMed Central (United Kingdom)

BackgroundAcute lower respiratory infections are the commonest cause of morbidity and potentially preventable mortality in Indigenous infants. Infancy is also a critical time for...Full Text Available

327

Radial keratoneuritis as a presenting sign in acanthamoeba keratitis.  

Science.gov (United States)

The visual outcomes of Acanthamoeba keratitis, a rare cause of corneal infection, can be devastating. This paper reports two contact lens wearers with severe pain and photophobia who presented to the emergency room. Biomicroscopy revealed radial keratoneuritis in both individuals. Tissue culture on a nonnutrient agar plate with Escherichia coli overlay resulted in a heavy growth of Acanthamoeba. The inpatient treatment included 0.02% polyhexamethylene biguanide, chlorhexidine, neomycin/polymyxin B/bacitracin (Neosporin), and oral fluconazole, which successfully controlled the corneal infection and improvement in the best corrected visual acuity in both patients. Infection did not recur during the 12-month follow-up period. Acanthamoeba keratitis can present as radial keratoneuritis, mimicking other common corneal infections resulting in diagnostic and treatment delays. Early diagnosis and prudent ...

2011-07-01

328

Pseudomonas aeruginosa selective adherence to and entry into human endothelial cells.  

UK PubMed Central (United Kingdom)

The pathogenesis of Pseudomonas aeruginosa disseminated infections depends on bacterial interaction with blood vessels. We have hypothesized that in order to traverse the endothelial barrier, bacteria...Full Text Available

1994-12-01

329

Prevalence of sexually transmissible pathogens in semen from asymptomatic male infertility patients with and without leukocytospermia  

UK PubMed Central (United Kingdom)

ObjectiveTo determine the prevalence of pathogens that cause sexually transmitted infections (STIs) in semen from asymptomatic male infertility patients with and...Full Text Available

2007-05-01

330

Prevalence and Characterization of Human Shigella Infections in Henan Province, China, in 2006 ?  

UK PubMed Central (United Kingdom)

In 2006, 3,531 fecal samples were collected from patients with diarrhea in Henan Province, China. A total of 467 (13.2%) Shigella strains were isolated and serotyped. Seventy-one...Full Text Available

2011-01-01

331

Pregravid BMI is associated with dietary restraint and psychosocial factors during pregnancy1  

UK PubMed Central (United Kingdom)

The objective was to investigate the association of pregravid weight status, dietary restraint and psychosocial factors during pregnancy. We used data from the Pregnancy, Infection and Nutrition...Full Text Available

2009-03-01

332

Pharmacokinetics and bioavailability of intravenous-to-oral enoxacin in elderly patients with complicated urinary tract infections.  

UK PubMed Central (United Kingdom)

The pharmacokinetics of oral fluoroquinolone antibiotics in normal volunteers have been studied extensively; however, limited patient data exist. Enoxacin steady-state pharmacokinetics and bioavailability...Full Text Available

1990-10-01

333

Phaeoisaria clematidis as a Cause of Keratomycosis  

UK PubMed Central (United Kingdom)

We report the first case of human infection by Phaeoisaria clematidis. This fungus caused a corneal ulcer in a Brazilian man who had previously suffered an eye injury. Diagnosis was...Full Text Available

2000-06-01

334

Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis  

UK PubMed Central (United Kingdom)

BackgroundThe long latent stage seen in syphilis, followed by chronic central nervous system infection and inflammation, can be explained by the persistence of atypical cystic and...Full Text Available

335

Persistence in herpes simplex virus infections.  

UK PubMed Central (United Kingdom)

Diseases of man caused by the virus of herpes simplex fall into two broad categories. The primary disease occurs only once in any individual's life and is caused by transmission of virus from an already...Full Text Available

1978-09-01

336

Pathogenesis of the Human Opportunistic Pathogen Pseudomonas aeruginosa PA14 in Arabidopsis1  

UK PubMed Central (United Kingdom)

The human opportunistic pathogen Pseudomonas aeruginosa strain PA14 is a multihost pathogen that can infect Arabidopsis. We found that PA14 pathogenesis in Arabidopsis involves the...Full Text Available

2000-12-01

337

Passive immunity to feline leukemia: evaluation of immunity from dams naturally infected and experimentally vaccinated.  

UK PubMed Central (United Kingdom)

Antibodies against feline leukemia virus (FeLV) and the feline oncornavirus-associated cell membrane antigen (FOCMA) were transferred from pregnant cats to their suckling kittens. All of these kittens...Full Text Available

1977-04-01

338

Outbreak of Infection with a Multiresistant Klebsiella pneumoniae Strain Associated with Contaminated Roll Boards in Operating Rooms  

UK PubMed Central (United Kingdom)

An outbreak with a multiresistant Klebsiella pneumoniae (MRKP) strain among seven patients admitted to the adult intensive care unit (ICU) of a regional teaching hospital in The Netherlands...Full Text Available

2005-10-01

339

Oral manifestations of HIV infection in children and adults receiving highly active anti-retroviral therapy [HAART] in Dar es Salaam, Tanzania  

UK PubMed Central (United Kingdom)

BackgroundThe aim of the study was to compare the prevalence and types of HIV-related oral lesions between children and adult Tanzanian patients on HAART with those not on HAART...Full Text Available

340

Novel Human Erythrovirus Associated with Transient Aplastic Anemia  

UK PubMed Central (United Kingdom)

Erythrovirus (formerly parvovirus) B19 causes a wide range of diseases in humans, including anemia due to aplastic crisis. Diagnosis of B19 infection relies on serology and the detection of viral DNA...Full Text Available

1999-08-01

341

Novel Approach for Differential Diagnosis of HIV Infections in the Face of Vaccine-Generated Antibodies  

UK PubMed Central (United Kingdom)

SummaryBecause increasing numbers of HIV vaccine candidates are being tested globally, it is essential to differentiate vaccine-from virus-induced antibodies. Most of the currently...Full Text Available

2006-11-01

342

Neural injury following stroke: are Toll-like receptors the link between the immune system and the CNS?  

UK PubMed Central (United Kingdom)

The CNS can exhibit features of inflammation in response to injury, infection or disease, whereby resident cells generate inflammatory mediators, including cytokines, prostaglandins, free radicals and...Full Text Available

2010-08-01

343

Mycobacterium tuberculosis Chaperonin 10 Is Secreted in the Macrophage Phagosome: Is Secretion Due to Dissociation and Adoption of a Partially Helical Structure at the Membrane?  

UK PubMed Central (United Kingdom)

To confirm that Mycobacterium tuberculosis chaperonin 10 (Cpn10) is secreted outside the live bacillus, infected macrophages were examined by electron microscopy. This revealed that...Full Text Available

2003-07-01

344

Mutant ?-Synuclein Overexpression Mediates Early Proinflammatory Activity  

UK PubMed Central (United Kingdom)

Microglia provide immune surveillance for the brain through both the removal of cellular debris and protection against infection by microorganisms and “foreign” molecules. Upon...Full Text Available

2009-10-01

345

Multidrug resistant Kluyvera ascorbata septicemia in an adult patient: a case report  

UK PubMed Central (United Kingdom)

IntroductionKluyvera ascorbata has become increasingly significant due to its potential to cause a wide range of infections, as well as its ability to transfer gene...Full Text Available

346

Morules in endometrial carcinoma and benign endometrial lesions differ from squamous differentiation tissue and are not infected with human papillomavirus  

UK PubMed Central (United Kingdom)

Background: Squamous differentiation/squamous metaplasia is often associated with endometrial adenocarcinoma and benign lesions, such as endometrial hyperplasia and chronic endometritis....Full Text Available

2004-09-01

347

Molecular Mechanistic Insights into the Endothelial Receptor Mediated Cytoadherence of Plasmodium falciparum-Infected Erythrocytes  

UK PubMed Central (United Kingdom)

Cytoadherence or sequestration is essential for the pathogenesis of the most virulent human malaria species, Plasmodium falciparum (P. falciparum). Similar to leukocyte-endothelium...Full Text Available

348

Molecular Evidence of Bartonella Infection in Domestic Dogs from Algeria, North Africa, by Polymerase Chain Reaction (PCR)  

UK PubMed Central (United Kingdom)

Bartonella species are being recognized as important bacterial human and canine pathogens, and are associated with multiple arthropod vectors. Bartonella DNA extracted...Full Text Available

2010-08-05

349

Molecular Epidemiology of Escherichia coli Producing Extended-Spectrum ?-Lactamases Isolated in Rome, Italy?  

UK PubMed Central (United Kingdom)

Escherichia coli strains producing extended-spectrum β-lactamases (ESBLs) are a major problem in many different hospitals worldwide, causing outbreaks as well as sporadic infections....Full Text Available

2008-01-01

350

Media reporting of tenofovir trials in Cambodia and Cameroon  

UK PubMed Central (United Kingdom)

BackgroundTwo planned trials of pre-exposure prophylaxis tenofovir in Cambodia and Cameroon to prevent HIV infection in high-risk populations were closed due to activist pressure...Full Text Available

351

Macrophage induction of T-suppressor cells in pesticide-exposed and protozoan-infected mice.  

UK PubMed Central (United Kingdom)

The use of infectious pathogens has allowed the detection of the development of synergism between pathogens and ubiquitous environmental chemical contaminants. This synergism has been demonstrated to...Full Text Available

1982-02-01

352

Liver Flukes: the Malady Neglected  

UK PubMed Central (United Kingdom)

Liver fluke disease is a chronic parasitic inflammatory disease of the bile ducts. Infection occurs through ingestion of fluke-infested, fresh-water raw fish. The most well-known species that cause...Full Text Available

2011-05-01

353

Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS  

UK PubMed Central (United Kingdom)

BackgroundHuman immunodeficiency virus type 1 (HIV-1) infection frequently causes neurologic disease, which is the result of viral replication and activation of macrophages and microglia...Full Text Available

354

Isolation of gram-positive rods that resemble but are clearly distinct from Actinomyces pyogenes from mixed wound infections.  

UK PubMed Central (United Kingdom)

Beginning in 1990, gram-positive rods resembling Actinomyces pyogenes were found with increasing frequency in mixed cultures from various infectious processes, most of them from patients with otitis,...Full Text Available

1993-05-01

355

Isolation of Mycoplasma pneumoniae from the human urogenital tract.  

UK PubMed Central (United Kingdom)

Mycoplasma pneumoniae is a common etiologic agent of lower respiratory tract infections in humans. However, it has been reported previously that the organism has occasionally been isolated from sites...Full Text Available

1995-11-01

356

Intragenomic conflict in populations infected by Parthenogenesis Inducing Wolbachia ends with irreversible loss of sexual reproduction  

UK PubMed Central (United Kingdom)

BackgroundThe maternally inherited, bacterial symbiont, parthenogenesis inducing (PI) Wolbachia, causes females in some haplodiploid insects to produce daughters...Full Text Available

357

Intracellular ribonucleoprotein complexes of visna virus are infectious.  

UK PubMed Central (United Kingdom)

Sheep choroid plexus cells infected with visna virus produce intracytoplasmic viral ribonucleoprotein complexes with sedimentation values of 120S to 200S and buoyant densities of 1.29 to 1.32 g/cm3....Full Text Available

1982-06-01

358

Interactions of Antibiotics and Methanolic Crude Extracts of Afzelia Africana (Smith.) Against Drug Resistance Bacterial Isolates  

UK PubMed Central (United Kingdom)

Infection due to multidrug resistance pathogens is difficult to manage due to bacterial virulence factors and because of a relatively limited choice of antimicrobial agents. Thus, it is imperative to...Full Text Available

359

Inflammatory Bowel Disease in Children, an Evolving Problem in Kuwait  

UK PubMed Central (United Kingdom)

Background/Aims:Inflammatory bowel disease (IBD) was previously thought a rare disease among children in Kuwait since most diarrhea cases were attributed to infections....Full Text Available

2011-09-01

360

Infection of Dendritic Cells by a ?2-Herpesvirus Induces Functional Modulation1  

UK PubMed Central (United Kingdom)

The murine γ-herpesvirus-68 (γHV68) establishes viral latency in dendritic cells (DCs). In the present study, we examined the specific consequences...Full Text Available

2005-09-01

361

Infected foot ulcers in male and female diabetic patients: a clinico-bioinformative study  

UK PubMed Central (United Kingdom)

BackgroundThe study aimed at (i) characterizing the mode of transmission of blaCTX-M and blaTEM-1 among extended-spectrum-β-lactamase...Full Text Available

362

Increased prevalence of antibodies to enteropathogenic Yersinia enterocolitica virulence proteins in relatives of patients with autoimmune thyroid disease  

UK PubMed Central (United Kingdom)

Infections have been implicated in the pathogenesis of a number of autoimmune diseases, and Yersinia enterocolitica (YE) might play a role in the development of autoimmune thyroid disease...Full Text Available

2003-05-01

363

Inactivation and Heat Stabilization of Poliovirus by 2-Thiouracil 1  

UK PubMed Central (United Kingdom)

Treatment of poliovirus Type I with 10−3m 2-thiouracil (2-TU) resulted in the inactivation of greater than 90% of the virus infectivity and stabilization of approximately...Full Text Available

1967-08-01

364

In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators  

UK PubMed Central (United Kingdom)

African trypanosomes exert significant morbidity and mortality in man and livestock. Only a few drugs are available for the treatment of trypanosome infections and therefore, the development of new...Full Text Available

365

Impact of Plasmodium falciparum infection on the frequency of moderate to severe anaemia in children below 10 years of age in Gabon  

UK PubMed Central (United Kingdom)

BackgroundImproving the understanding of childhood malarial anaemia may help in the design of appropriate management strategies.MethodsA...Full Text Available

366

Immune activation and IL-12 production during acute/early HIV infection in the absence and presence of highly active, antiretroviral therapy  

UK PubMed Central (United Kingdom)

Suppressed IL-12 production and maladaptive immune activation, both of which are ameliorated by successful highly active antiretroviral therapy (HAART), are thought to play important roles in the immunopathogenesis...Full Text Available

2008-12-01

367

Illthrift in Suckling Lambs Secondary to Umbilical Infections and Possible Implication of Cryptosporidiosis as a Risk Factor  

UK PubMed Central (United Kingdom)

Illthrift was observed in 20/60 lambs aged 40–45 days in a dairy sheep flock in Greece. Cryptosporidiosis had been diagnosed and successfully treated with halofuginone lactate a month earlier....Full Text Available

368

Identification of CTX-M-Type Extended-Spectrum-?-Lactamase Genes Using Real-Time PCR and Pyrosequencing?  

UK PubMed Central (United Kingdom)

CTX-M extended-spectrum β-lactamases (ESBLs) are increasingly prevalent worldwide among Escherichia coli bacteria, mostly in community-acquired urinary tract infections. Finding...Full Text Available

2007-01-01

369

Identification and characterization of plasmids from the western aster yellows mycoplasmalike organism.  

UK PubMed Central (United Kingdom)

Supercoiled double-stranded DNA molecules (plasmids) were isolated from plants infected with three laboratory strains of western aster yellows mycoplasma-like organism (AY-MLO) by using cesium chloride-ethidium...Full Text Available

1990-03-01

370

Identification and Characterization of CPS1 as a Hyaluronic Acid Synthase Contributing to the Pathogenesis of Cryptococcus neoformans Infection?  

UK PubMed Central (United Kingdom)

Cryptococcus neoformans is a pathogenic yeast that often causes devastating meningoencephalitis in immunocompromised individuals. We have previously identified the C. neoformans...Full Text Available

2007-08-01

371

INFLUENCE OF PERCEIVED SECONDARY STIGMA AND FAMILY ON THE RESPONSE TO HIV INFECTION AMONG INJECTION DRUG USERS IN VIETNAM  

UK PubMed Central (United Kingdom)

The full impact of secondary stigma (stigma directed at family) on an HIV-positive individual is unknown. This qualitative research explores perceptions of secondary stigma in the Vietnamese...Full Text Available

2010-12-01

372

Human spumaretrovirus-related sequences in the DNA of leukocytes from patients with Graves disease.  

UK PubMed Central (United Kingdom)

Viruses, and more particularly retroviruses, have been postulated to play a role in the pathogenesis of autoimmune diseases. In a search for spumaretrovirus infection markers, we screened a group of...Full Text Available

1992-11-01

373

Human bone matrix gelatin as a clinical alloimplant. A retrospective review of 160 cases.  

Science.gov (United States)

Bone matrix gelatin, prepared by sequential chemical treatment including decalcification with 0.6 N hydrochloric acid [9], was used as an alloimplant for the treatment of benign bone tumours, tumorous conditions of bone, acetabular dysplasia, delayed union, traumatic bone defects and other disorders. The bone matrix gelatin implanted into bone defects was incorporated successfully in 98% of implantations, excluding cases of infection, tumour recurrence and recurrence of tumorous conditions. The material was also implanted into ten bone sites as an onlay but in five it was resorbed without new bone formation. The incorporation of the bone matrix gelatin into the recipient bed was completed from 6 to 33 months (average 14.9 months) after implantation. Wound infection complicated 5 of 165 implantations (3%) in previously uninfected sites. Low grade fever persisting after the tenth post-operative day (a probable sign of immunological reaction) ...

1985-01-01

374

Helicobacter pylori infection, oncogenic pathways and epigenetic mechanisms in gastric carcinogenesis  

UK PubMed Central (United Kingdom)

Chronic colonization of the human stomach by Helicobacter pylori, a Gram-negative bacterium, is the major cause of chronic gastritis, peptic ulcers and gastric cancer. Recent...Full Text Available

2010-05-01

375

HIV prevention in prisons and jails: obstacles and opportunities.  

UK PubMed Central (United Kingdom)

High rates of human immunodeficiency virus (HIV) infection among jail and prison inmates suggest that HIV prevention efforts should focus on incarcerated populations. Overcrowding, the high prevalence...Full Text Available

1994-09-01

376

Gonorrhoea in men: clinical and diagnostic aspects.  

UK PubMed Central (United Kingdom)

AIM: To review the features of gonococcal infection in men in the 1990s. METHODS: A retrospective study of all men with gonorrhoea presenting to an inner city department of genitourinary medicine in...Full Text Available

1996-12-01

377

Genomic Expression Libraries for the Identification of Cross-Reactive Orthopoxvirus Antigens  

UK PubMed Central (United Kingdom)

Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young non-vaccinated persons have renewed interest in this zoonotic disease. Usually causing...Full Text Available

378

Genetic studies of fertility and pathogenicity in Magnaporthe grisea (Pyricularia oryzae)  

Energy Technology Data Exchange (ETDEWEB)

Crosses between field isolates of Magnaporthe grisea (anamorph, Pyricularia oryzae Cav. and Pyricularia grisea) have led to the development of fertile laboratory strains that infect goosegrass and/or weeping lovegrass. These strains may now be utilized in a rigorous genetic analysis of host species specificity and general pathogenicity. Attempts to improve the fertility of rice pathogens for the goal of undertaking a genetic analysis of host cultivar specificity have so far been unsuccessful. Crosses between M. grisea strains that infect rice, goosegrass or weeping lovegrass demonstrate that host species specificity differences between field isolates of this fungus in some cases have a complete genetic basis, and in other cases have a simple genetic basis. Crosses between a field isolate of the pathogen that infects weeping lovegrass and a field isolate that infects goosegrass have resulted in the ...

1984-01-01

379

Genetic heterogeneity in human T-cell leukemia/lymphoma virus type II.  

UK PubMed Central (United Kingdom)

DNA from the peripheral blood mononuclear cells of 17 different individuals infected with human T-cell lymphoma/leukemia virus type II (HTLV-II) was successfully amplified by the polymerase chain reaction...Full Text Available

1993-03-01

380

Genetic Evidence for Inhibition of Bacterial Division Protein FtsZ by Berberine  

UK PubMed Central (United Kingdom)

BackgroundBerberine is a plant alkaloid that is widely used as an anti-infective in traditional medicine. Escherichia coli exposed to berberine form filaments, suggesting...Full Text Available

381

Genetic Diversity in Blastomyces dermatitidis: Implications for PCR Detection in Clinical and Environmental Samples  

UK PubMed Central (United Kingdom)

SummaryBlastomycosis is a serious and potentially fatal infection by the thermally dimorphic fungus Blastomyces dermatitidis. PCR assays targeting the BAD-1 virulence...Full Text Available

2010-03-01

382

Gallium Disrupts Iron Uptake by Intracellular and Extracellular Francisella Strains and Exhibits Therapeutic Efficacy in a Murine Pulmonary Infection Model ?  

UK PubMed Central (United Kingdom)

Francisella tularensis requires iron (Fe) for growth, but the biologic sources of Fe for this organism are largely unknown. We found that Francisella sp. growing in...Full Text Available

2010-01-01

383

GROWTH REGULATION IN ROUS SARCOMA VIRUS INFECTED CHICKEN EMBRYO FIBROBLASTS: THE ROLE OF THE src GENE  

Energy Technology Data Exchange (ETDEWEB)

We report here a study of the mechanisms leading to loss of growth control in chicken embryo fibroblasts transformed by Rous sarcoma virus (RSV). We have been particularly concerned with the role of the src gene in this process, and have used RSV mutants temperature sensitive (ts) for transformation to investigate the nature of the growth regulatory lesion. The two principal findings were (1) the stationary phase of the cell cycle (G{sub 1}) in chick embryo fibroblasts seems to have two distinct regulatory compartments (using the terminology of Brooks et al. we refer to these as 'Q' and 'A' states). When rendered stationary at 41.5 C by serum deprivation, normal cells enter a Q state, but cells infected with the ts-mutant occupy an A state. (2) Whereas normal cells can occupy either state depending on culture conditions, the ts-infected cells, at 41.5 C, do not seem to enter Q even though a known src gene ...

1980-07-01

384

Fungal Infection in Patients with Serpiginous Choroiditis or Acute Zonal Occult Outer Retinopathy?  

UK PubMed Central (United Kingdom)

The etiologies of a number of retinopathies, including serpiginous choroiditis and acute zonal occult outer retinopathy (AZOOR), remain uncertain. Recently, we provided evidence that AZOOR is caused...Full Text Available

2008-01-01

385

Fluorescence amplified fragment length polymorphism for subtyping of genotypes of Acanthamoeba isolated from patients with keratitis  

UK PubMed Central (United Kingdom)

Background & objectives:Acanthamoeba keratitis (AK) is a painful and vision-threatening ocular infection. The differentiation of Acanthamoeba...Full Text Available

2011-01-01

386

Flock infection and transport as sources of salmonellae in broiler chickens and carcasses.  

UK PubMed Central (United Kingdom)

Cultural monitoring was used to determine the incidence and sources of salmonellae in a 4160-bird broiler flock raised on litter in 32 pens. Twenty-five of the pens remained apparently free of salmonellae...Full Text Available

1980-07-01

387

Five year prospective study of plasma renin activity and blood pressure in patients with longstanding reflux nephropathy.  

UK PubMed Central (United Kingdom)

Eight of 100 normotensive children who had pyelonephritic scarring secondary to urinary infection and vesicoureteric reflux were found in an earlier study to have increased plasma renin activity (PRA)....Full Text Available

1987-07-01

388

First Culture Isolation of Borrelia lonestari, Putative Agent of Southern Tick-Associated Rash Illness  

UK PubMed Central (United Kingdom)

Southern tick-associated rash illness (STARI) is a Lyme disease-like infection described in patients in the southeastern and south-central United States, where classic Lyme disease is relatively rare....Full Text Available

2004-03-01

389

Field application of a colorimetric method of assaying chloroquine and desethylchloroquine in urine  

UK PubMed Central (United Kingdom)

In a study in western Kenya of malaria-infected adult women who had been treated with chloroquine, we compared the level of chloroquine and its principal metabolite, desethylchloroquine, in urine,...Full Text Available

1988-01-01

390

Factors Predicting and Reducing Mortality in Patients with Invasive Staphylococcus aureus Disease in a Developing Country  

UK PubMed Central (United Kingdom)

BackgroundInvasive Staphylococcus aureus infection is increasingly recognised as an important cause of serious sepsis across the developing world, with mortality...Full Text Available

391

Expression of SV40 virus large T antigen by recombinant adenoviruses activates proliferation of corneal endothelium in vitro.  

UK PubMed Central (United Kingdom)

Infection with the Ad5-SVR4 virus was used to introduce the large T antigen encoding region of the SV40 virus into bovine and human corneal endothelial cells. Expression of large T antigen occurred...Full Text Available

1993-04-01

392

Experimental avian paramyxovirus serotype-3 infection in chickens and turkeys  

UK PubMed Central (United Kingdom)

Avian paramyxoviruses (APMV) are divided into nine serotypes. Newcastle disease virus (APMV-1) is the most extensively characterized, while relatively little information is available for the other APMV...Full Text Available

2010-09-01

393

Exotic Small Mammals as Potential Reservoirs of Zoonotic Bartonella spp.  

UK PubMed Central (United Kingdom)

To evaluate the risk for emerging human infections caused by zoonotic Bartonella spp. from exotic small mammals, we investigated the prevalence of Bartonella spp. in...Full Text Available

2009-04-01

394

Evidence of an inflammatory-like response in non-normally pigmented tissues of two scleractinian corals  

UK PubMed Central (United Kingdom)

Increasing evidence of links between climate change, anthropogenic stress and coral disease underscores the importance of understanding the mechanisms by which reef-building corals resist infection...Full Text Available

2008-12-07

395

Evaluation of two commercial jet nebulisers and three compressors for the nebulisation of antibiotics.  

UK PubMed Central (United Kingdom)

Nebulised antibiotics have been shown to be beneficial in the treatment of lung infections in cystic fibrosis. Studies on the efficiency of nebuliser systems are constantly required in view of the large...Full Text Available

1994-10-01

396

Evaluation of the OptiMAL Test for Rapid Diagnosis of Plasmodium vivax and Plasmodium falciparum Malaria  

UK PubMed Central (United Kingdom)

The development of rapid and specific diagnostic tests to identify individuals infected with malaria is of paramount importance in efforts to control the severe public health impact of this disease....Full Text Available

1998-01-01

397

Entry and release of transmissible gastroenteritis coronavirus are restricted to apical surfaces of polarized epithelial cells.  

UK PubMed Central (United Kingdom)

The transmissible gastroenteritis coronavirus (TGEV) infects the epithelial cells of the intestinal tract of pigs, resulting in a high mortality rate in piglets. This study shows the interaction of...Full Text Available

1994-12-01

398

Elucidation of the Pharmacokinetic/Pharmacodynamic Determinant of Colistin Activity against Pseudomonas aeruginosa in Murine Thigh and Lung Infection Models?  

UK PubMed Central (United Kingdom)

Colistin is increasingly used as last-line therapy against Gram-negative pathogens. The pharmacokinetic (PK)/pharmacodynamic (PD) index that best correlates with the efficacy of colistin remains undefined....Full Text Available

2010-03-01

399

Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus  

UK PubMed Central (United Kingdom)

One-third of botanical remedies from southern Italy are used to treat skin and soft tissue infection (SSTI). Staphylococcus aureus, a common cause of SSTI, has generated increasing...Full Text Available

2008-08-13

400

Effect of precalving intramammary treatment with pirlimycin in nulliparous Holstein heifers  

UK PubMed Central (United Kingdom)

A clinical trial was conducted to determine whether prepartum intramammary pirlimycin reduces the proportion of nulliparous heifers with intramammary infection (IMI) during early lactation and improves...Full Text Available

2007-10-01

401

Effect of clindamycin on neutrophil killing of gram-negative periodontal bacteria.  

UK PubMed Central (United Kingdom)

Periodontal diseases are infections of the tissues supporting the dentition. Recognition that relatively specific microfloras are associated with distinct clinical forms of periodontal disease has prompted...Full Text Available

1988-10-01

402

Effect of a mixture of micronutrients, but not of bovine colostrum concentrate, on immune function parameters in healthy volunteers: a randomized placebo-controlled study  

UK PubMed Central (United Kingdom)

BackgroundSupplementation of nutritional deficiencies helps to improve immune function and resistance to infections in malnourished subjects. However, the suggested benefits of dietary...Full Text Available

403

Diterpene Biosynthesis in Maize Seedlings in Response to Fungal Infection 1  

UK PubMed Central (United Kingdom)

A cell-free system which catalyzes the biosynthesis of terpene hydrocarbons when supplemented with mevalonate, Mn2+, and ATP was prepared from the scutellum-embryonic axis region of maize...Full Text Available

1979-09-01

404

Distribution Frequency of Pathogenic Bacteria Isolated from Cutaneus Leishmaniasis Lesions  

UK PubMed Central (United Kingdom)

Cutaneous leishmaniasis (CL) is a parasitic disease characterized by single or multiple ulcerations. Secondary bacterial infections are one of the complications that can increase the tissue destruction...Full Text Available

2008-09-01

405

Differential recognition of viral RNA by RIG-I  

UK PubMed Central (United Kingdom)

Retinoic acid inducible gene I (RIG-I) is a pattern recognition receptor (PRR) responsible for detection of nucleic acids from pathogens in the cytoplasm of infected cells and induction of type I interferon...Full Text Available

2011-03-01

406

Diagnostic comparison of malaria infection in peripheral blood, placental blood and placental biopsies in Cameroonian parturient women  

UK PubMed Central (United Kingdom)

BackgroundIn sub-Saharan Africa, Plasmodium falciparum malaria in pregnancy presents an enormous diagnostic challenge. The epidemiological and clinical relevance...Full Text Available

407

Determinants of antiviral treatment initiation in a hepatitis C-infected population benefiting from universal health care coverage  

UK PubMed Central (United Kingdom)

BACKGROUND AND AIMS:In view of increasing therapeutic efficacy, the delivery of hepatitis C virus (HCV) antiviral treatment is expected to increase. Yet practical experience reveals...Full Text Available

2007-06-01

408

Detection of hepatitis B virus DNA among accepted blood donors in Nanjing, China  

UK PubMed Central (United Kingdom)

BackgroundPosttransfusion hepatitis B virus (HBV) infection still occurs although its incidence has been substantially reduced since the introduction of screening of hepatitis B...Full Text Available

409

Detection of Sub-Clinical CWD Infection in Conventional Test-Negative Deer Long after Oral Exposure to Urine and Feces from CWD+ Deer  

UK PubMed Central (United Kingdom)

BackgroundChronic wasting disease (CWD) of cervids is a prion disease distinguished by high levels of transmissibility, wherein bodily fluids and excretions are thought to play an...Full Text Available

410

Defining and measuring the costs of the HIV epidemic to business firms.  

UK PubMed Central (United Kingdom)

Most published estimates of the costs of the epidemic of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) have been developed from the societal perspective,...Full Text Available

1994-05-01

411

Defective hepatitis B virus particles are generated by packaging and reverse transcription of spliced viral RNAs in vivo.  

UK PubMed Central (United Kingdom)

Generation of replicative defective viruses is frequently observed during viral infections. We now report that encapsidation and reverse transcription of spliced viral RNA is an additional mechanism...Full Text Available

1991-10-01

412

Current status of a hepatitis C vaccine: encouraging results but significant challenges ahead  

DEFF Research Database (Denmark)

Persistent hepatitis C virus (HCV) infection affects 170 million people worldwide. Acute HCV infection is often asymptomatic, but many infected individuals develop persistent infections that may lead to development of end-stage liver diseases, including liver cirrhosis and hepatocellular carcinoma. Thus, an HCV vaccine that could significantly lower the chronicity rate would have a major impact on the disease burden. Unfortunately, HCV is a highly mutable virus, and escape mutations can undermine vaccine-induced virus-specific immunity. Also, HCV exists as multiple genotypes, and so genotype-specific vaccines might be required to achieve broad protection. Finally, vaccine development has been hampered by the lack of a small animal model and cell culture systems, but these are currently being established. Despite these obstacles, several vaccine candidates tested in the chimpanzee HCV model have shown ...

2007-01-01

413

Coping with crowds: Density-dependent disease resistance in desert locusts  

UK PubMed Central (United Kingdom)

Parasite transmission generally exhibits some form of positive density dependence. Thus, as population density increases, so too does the per capita risk of becoming infected. Under...Full Text Available

2002-04-16

414

Consequences of unlocking the cardiac myosin molecule in human myocarditis and cardiomyopathies  

UK PubMed Central (United Kingdom)

Myocarditis, often initiated by viral infection, may progress to autoimmune inflammatory heart disease, dilated cardiomyopathy and heart failure. Although cardiac myosin is a dominant autoantigen...Full Text Available

2008-09-01

415

Complexes of hepatitis B surface antigen and immunoglobulin M in the sera of patients with hepatitis B virus infection.  

UK PubMed Central (United Kingdom)

Hepatitis B surface antigen (HBsAg) bound to immunoglobulin M (IgM) was detected in sera of HBsAg carriers by a radioimmunoassay based on selective absorption of the immunoglobulin on a solid phase...Full Text Available

1983-09-01

416

Complement Factor H-Related Proteins CFHR2 and CFHR5 Represent Novel Ligands for the Infection-Associated CRASP Proteins of Borrelia burgdorferi  

UK PubMed Central (United Kingdom)

BackgroundOne virulence property of Borrelia burgdorferi is its resistance to innate immunity, in particular to complement-mediated killing. Serum-resistant B....Full Text Available

417

Comparison of geographical strains of Schistosoma mansoni in the rhesus monkey*  

UK PubMed Central (United Kingdom)

Rhesus monkeys were infected with strains of Schistosoma mansoni from Puerto Rico, St Lucia, Brazil, and Tanzania. Monkeys were killed 11-14 weeks after exposure to 600-650 cercariae....Full Text Available

1972-01-01

418

Comparison of geographical strains of Schistosoma mansoni in the mouse*  

UK PubMed Central (United Kingdom)

Mice were killed 7, 11, 19, and 27 weeks after infection with strains of Schistosoma mansoni from Puerto Rico, Brazil, St Lucia, and Tanzania. The percentage recovery of adult worms...Full Text Available

1972-01-01

419

Comparison of azlocillin, ceftizoxime, cefoxitin, and amikacin alone and in combination against Pseudomonas aeruginosa in a neutropenic-site rabbit model.  

UK PubMed Central (United Kingdom)

The efficacy of beta-lactam antibiotics and amikacin alone and in various combinations against Pseudomonas aeruginosa was studied in a rabbit model simulating a closed-space infection in a locally neutropenic...Full Text Available

1984-05-01

420

Comparative analysis of differentially expressed genes in normal and white spot syndrome virus infected Penaeus monodon  

UK PubMed Central (United Kingdom)

BackgroundWhite spot syndrome (WSS) is a viral disease that affects most of the commercially important shrimps and causes serious economic losses to the shrimp farming industry worldwide....Full Text Available

421

Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria  

UK PubMed Central (United Kingdom)

There is growing epidemiological and molecular evidence that ABO blood group affects host susceptibility to severe Plasmodium falciparum infection. The high frequency of common...Full Text Available

2008-02-15

422

Clostridium difficile is not associated with outbreaks of viral gastroenteritis in the elderly in the Netherlands  

UK PubMed Central (United Kingdom)

The coincidental increase in norovirus outbreaks and Clostridium difficile infection (CDI) raised the question of whether these events could be related, e.g. by enhancing spread by...Full Text Available

2010-06-01

423

Clinical perspective on aztreonam lysine for inhalation in patients with cystic fibrosis  

UK PubMed Central (United Kingdom)

Progressive obstructive lung disease is a characteristic component of cystic fibrosis (CF). It is the pulmonary manifestations, including obstruction and endobronchial infection, which directly contribute...Full Text Available

424

Chlamydia trachomatis Load at Matched Anatomic Sites: Implications for Screening Strategies?  

UK PubMed Central (United Kingdom)

Urethral and endocervical swabs and self-collected vaginal swabs (SCVSs) and urine specimens are all used as samples for diagnosis of urogenital infection with Chlamydia trachomatis....Full Text Available

2007-05-01

425

Characterization of the 5'-terminal cap structures of early simian virus 40 mRNA.  

UK PubMed Central (United Kingdom)

Early simian virus 40-specific mRNA was isolated from lytically infected and stably transformed cells and analyzed with respect to the 5'-terminal cap content. An analogous diversity of capped structures...Full Text Available

1980-09-01

426

Characterization of a fatty acid and retinol binding protein orthologue from the hookworm Ancylostoma ceylanicum?  

UK PubMed Central (United Kingdom)

Hookworms, bloodfeeding intestinal nematodes, infect nearly one billion people in resource limited countries and are a leading cause of anemia and malnutrition. Like other nematodes, hookworms...Full Text Available

2009-12-01

427

Breast cancer and human papillomavirus infection: No evidence of HPV etiology of breast cancer in Indian women  

UK PubMed Central (United Kingdom)

BackgroundTwo clinically relevant high-risk HPV (HR-HPV) types 16 and 18 are etiologically associated with the development of cervical carcinoma and are also reported to be present...Full Text Available

428

Breaking the 1000-gene barrier for Mimivirus using ultra-deep genome and transcriptome sequencing  

UK PubMed Central (United Kingdom)

BackgroundMimivirus, a giant dsDNA virus infecting Acanthamoeba, is the prototype of the mimiviridae family, the latest addition to the family of the nucleocytoplasmic...Full Text Available

429

Bacterial lipopolysaccharide induces an endocrine switch from prostaglandin F2? to prostaglandin E2 in bovine endometrium  

UK PubMed Central (United Kingdom)

Escherichia coli infection of the endometrium causes uterine disease after parturition and is associated with prolonged luteal phases of the ovarian cycle in cattle. Termination...Full Text Available

2009-04-01

430

Bacterial infections in suspected cutaneous leishmaniasis lesions.  

UK PubMed Central (United Kingdom)

In Iran, microscopic examination of skin scrapings from 2202 individuals with clinically diagnosed cutaneous leishmaniasis (CL) lesions revealed the presence of amastigotes in 1123 cases (51.0%). Bacteriological...Full Text Available

1990-01-01

431

Bacteraemia during prostatectomy and other transurethral operations: influence of timing of antibiotic administration.  

UK PubMed Central (United Kingdom)

The relation between the timing of prophylactic antibiotic administration and the occurrence of bacteraemia during transurethral operations was studied in 112 patients whose urine was infected before...Full Text Available

1984-06-01

432

Apoptosis induced by parasitic diseases  

UK PubMed Central (United Kingdom)

Fatalities caused by parasitic infections often occur as a result of tissue injury that results from a form of host-cell death known as apoptosis. However, instead of being pathogenic, parasite-induced...Full Text Available

433

Antiviral Inhibition of Enveloped Virus Release by Tetherin/BST-2: Action and Counteraction  

UK PubMed Central (United Kingdom)

Tetherin (BST2/CD317) has been recently recognized as a potent interferon-induced antiviral molecule that inhibits the release of diverse mammalian enveloped virus particles from infected cells. By...Full Text Available

434

Antimalarial activities and subacute toxicity of RC-12, a 4-amino-substituted pyrocatechol.  

UK PubMed Central (United Kingdom)

RC-12 [1,2-dimethoxy-4-(bis-diethylaminoethyl)-amino-5-bromobenzene] was evaluated for prophylactic, radical curative, and suppressive activities against infections with Plasmodium cynomolgi and subacute...Full Text Available

1985-11-01

435

Anti-Apoptotic Genes in the Survival of Monocytic Cells During Infection  

UK PubMed Central (United Kingdom)

Macrophages are cells of the immune system that protect organisms against invading pathogens by fulfilling critical roles in innate and adaptive immunity and inflammation. They originate from circulating...Full Text Available

2009-08-01

436

Antagonist HIV-1 Gag Peptides Induce Structural Changes in HLA B8  

UK PubMed Central (United Kingdom)

In the cellular immune response, recognition by CTL-TCRs of viral antigens presented as peptides by HLA class I molecules, triggers destruction of the virally infected cell (Townsend, A.R.M., J. Rothbard,...Full Text Available

1996-12-01

437

Age-Stratified Bayesian Analysis To Estimate Sensitivity and Specificity of Four Diagnostic Tests for Detection of Cryptosporidium Oocysts in Neonatal Calves?  

UK PubMed Central (United Kingdom)

There is no gold standard diagnostic test for the detection of bovine cryptosporidiosis. Infection is usually highest in 2-week-old calves, and these calves also excrete high numbers of oocysts. These...Full Text Available

2011-01-01

438

Absence of detectable xenotropic murine leukemia virus-related virus in plasma or peripheral blood mononuclear cells of human immunodeficiency virus Type 1-infected blood donors or individuals in Africa  

British Library Electronic Table of Contents (United Kingdom)

BACKGROUND: Since the identification of xenotropic murine leukemia virus-related virus (XMRV) in prostate cancer patients in 2006 and in chronic fatigue syndrome patients in 2009, conflicting findings have been reported regarding its etiologic role in human diseases and prevalence in general populations. In this study, we screened both plasma and peripheral blood mononuclear cells (PBMNCs) collected in Africa from blood donors and human immunodeficiency virus Type 1 (HIV-1)-infected individuals to gain evidence of XMRV infection in this geographic region. STUDY DESIGN AND METHODS: A total of 199 plasma samples, 19 PBMNC samples, and 50 culture supernatants from PBMNCs of blood donors from Cameroon found to be infected with HIV-1 and HIV-1 patients from Uganda were screened for XMRV infecti...

2011-01-01

439

A small RNA promotes siderophore production through transcriptional and metabolic remodeling  

UK PubMed Central (United Kingdom)

Siderophores are essential factors for iron (Fe) acquisition in bacteria during colonization and infection of eukaryotic hosts, which restrain iron access through iron-binding protein, such as lactoferrin...Full Text Available

2010-08-24

440

A report of clinical trial conducted on Toto ointment and soap products.  

UK PubMed Central (United Kingdom)

OBJECTIVE: The efficacy of Toto ointment and soap on common skin disorders was tested. METHODOLOGY: A cohort of Nigerians with common skin conditions such as fungal and bacterial skin infections, scabies,...Full Text Available

2003-01-01

441

A cross-sectional study of Tritrichomonas foetus infection among healthy cats at shows in Norway  

UK PubMed Central (United Kingdom)

BackgroundIn recent years, the protozoan Tritrichomonas foetus has been recognised as an important cause of chronic large-bowel diarrhoea in purebred cats in many...Full Text Available

442

A Strong Case for Viral Genetic Factors in HIV Virulence  

UK PubMed Central (United Kingdom)

HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four...Full Text Available

443

A Serological Survey of Sera from Domestic Animals on Easter Island  

UK PubMed Central (United Kingdom)

Animals' sera collected on Easter Island from December 1964 to February 1965 were tested by appropriate methods for the presence of antibodies to various infections. These included, ornithosis, Q-fever,...Full Text Available

1968-04-01

444

A Rapid Murine Coma and Behavior Scale for Quantitative Assessment of Murine Cerebral Malaria  

UK PubMed Central (United Kingdom)

BackgroundCerebral malaria (CM) is a neurological syndrome that includes coma and seizures following malaria parasite infection. The pathophysiology is not fully understood and cannot...Full Text Available

445

A Point Mutation in a Domain of Gamma Interferon Receptor 1 Provokes Severe Immunodeficiency  

UK PubMed Central (United Kingdom)

Gamma interferon (IFN-γ) and the cellular responses induced by it are essential for controlling mycobacterial infections. Most patients bearing an IFN-γ receptor ligand-binding chain...Full Text Available

2001-01-01

446

A Dominant Role for the Immunoproteasome in CD8+ T Cell Responses to Murine Cytomegalovirus  

UK PubMed Central (United Kingdom)

Murine cytomegalovirus (MCMV) is an important animal model of human cytomegalovirus (HCMV), a β-Herpesvirus that infects the majority of the world's population and causes disease in neonates...Full Text Available

447

A Case of Neurocysticercosis in Entire Spinal Level  

UK PubMed Central (United Kingdom)

Cysticercosis is the most common parasitic infection affecting the central nervous system. Spinal neurocysticercosis (NCC) is very rare compared with intracranial NCC and requires more aggressive management...Full Text Available

2010-10-01

448

X-ray phase imaging using a X-ray tube with a small focal spot. Improvement of image quality in mammography  

International Nuclear Information System (INIS)

Phase contrast X-ray imaging has been studied intensively using X-rays from synchrotron radiation and micro-focus X-ray tubes. However, these studies have revealed the difficulty of this technique's application to practical medical imaging. We have created a phase contrast imaging technique using a molybdenum X-ray tube with a small focal spot size for mammography. We identified the radiographic conditions in phase contrast magnification mammography with a screen-film system, where edge effect due to phase contrast overcomes geometrical unsharpness caused by the 0.1 mm-focal spot of a molybdenum X-ray tube. The edge enhancement due to phase imaging was observed in an image of a plastic tube, and then geometrical configuration of the X-ray tube, the object and the screen-film system was determined for phase imaging of mammography. In order to investigate a ...

2002-03-01

449

Phantom and animal imaging studies using PLS synchrotron X-rays  

CERN Document Server

Ultra-high resolution radiographs can be obtained using synchrotron X-rays. A collaboration team consisting of K-JIST, POSTECH and YUMC has recently commissioned a new beamline (5C1) at Pohang Light Source (PLS) in Korea for medical applications using phase contrast radiology. Relatively simple image acquisition systems were set up on 5C1 beamline, and imaging studies were performed for resolution test patterns, mammographic phantom, and animals. Resolution test patterns and mammographic phantom images showed much better image resolution and quality with the 5C1 imaging system than the mammography system. Both fish and mouse images with 5C1 imaging system also showed much better image resolution with great details of organs and anatomy compared to those obtained with a conventional mammography system. A simple and ...

2001-01-01

450

Combining anatomy and function: the path to true image fusion  

Energy Technology Data Exchange (ETDEWEB)

Modern imaging technologies visualize different aspects of disease in a non-invasive way. Considerable progress has been made in the fusion of images from different imaging modalities using software approaches. One goal of fusion software is to align anatomical and functional images and allow improved spatial localization of abnormalities. The resulting correlation of the anatomical and functional images may clarify the nature of the abnormality and help diagnose or stage the underlying disease. Whereas successful image fusion software has been developed for the brain, only limited success has been achieved for image alignment in other parts of the body. The development and current status of alternative approaches are presented. Dual-modality imaging is described with devices where two modalities are combined and mounted ...

2001-10-01

451

Approximate fuzzy C-means (AFCM) cluster analysis of medical magnetic resonance image (MRI) data  

International Nuclear Information System (INIS)

The authors describe the application of an approximate fuzzy C-means (AFCM) clustering algorithm as a data dimension reduction approach to medical magnetic resonance images (MRI). Image data consisted of one T1-weighted, two T2-weighted, and one T2*-weighted (magnetic susceptibility) image for each cranial study and a matrix of 10 images generated from 10 combinations of TE and TR for each body lymphoma study. All images were obtained with a 1.5 Tesla imaging system (GE Signa). Analyses were performed on over 100 MR image sets with a variety of pathologies. The cluster analysis was operated in an unsupervised mode and computational overhead was minimized by utilizing a table look-up approach without adversely affecting accuracy. Image data were first segmented into 2 coarse clusters, each of which was then subdivided ...

452

The Immunity-related GTPase Irgm3 Relieves Endoplasmic Reticulum Stress Response during Coxsackievirus B3 Infection via a PI3K/Akt Dependent Pathway.  

Science.gov (United States)

The IRG protein Irgm3 preserves cell survival during coxsackievirus B3 (CVB3) infection. However, the molecular mechanisms are not clear. Here, we examined the effect of Irgm3 expression on ER stress triggered by pharmacological agents or CVB3 infection. In Tet-On/Irgm3 HeLa cells, Irgm3 expression suppressed either chemical- or CVB3-induced upregulation of glucose-regulated protein78. Further, Irgm3 strongly inhibited the activation of both the PERK and ATF6 pathways of ER stress responses, which further led to the diminished phosphorylation of eIF2?, reduced cleavage/activation of transcription factor SREBP1 and attenuated induction of proapoptotic genes CHOP and GADD34. These data were further supported by experiments using Irgm3 knockout mouse embryonic fibroblasts, in which the ER stress induced by CVB3 was not relieved due to the lack of Irgm3 expression. In addition, the tunicamycin-triggered ER stress promoted the subsequent CVB3 ...

2011-10-10

453

Characterization of monocyte differentiation-inducing (MDI) factors derived from human fetal membrane chorion cells undergoing apoptosis after influenza virus infection.  

Science.gov (United States)

Influenza virus infection during pregnancy has been implicated as one of cause of premature delivery, abortion and stillbirth. We have reported that cultured human fetal membrane chorion cells undergoing apoptosis by influenza virus infection secrete unidentified heat-stable monocyte differentiation-inducing (MDI) factors. In this study, cellular, biological and immunochemical characteristics of MDI factors were investigated using human monocytic leukemia THP-1 cells by nitroblue tetrazolium reduction and cell adhesion assays. The treatment of THP-1 cells with culture supernatants from the influenza virus-infected chorion cells induced the nitroblue tetrazolium reduction ability, which was inhibited by the addition of superoxide dismutase and diphenyleneiodonium chloride, an inhibitor for reduced nicotinamide adenine dinucleotide phosphate oxidase. The phenomenon was also observed in human peripheral blood monocytes and ...

2006-06-06

454

Visible Earth: Typhoon Aere  

Science.gov (United States)

NASA's Visible Earth catalog of NASA images and animations of our home planet.

457

Theoretical study of subwavelength imaging by acoustic metamaterial slabs  

CERN Document Server

We investigate theoretically subwavelength imaging by acoustic metamaterial slabs immersed in the liquid matrix. A near-field subwavelength image formed by evanescent waves is achieved by a designed metamaterial slab with negative mass density and positive modulus. A subwavelength real image is achieved by a designed metamaterial slab with simultaneously negative mass density and modulus. These results are expected to shed some lights on designing novel devices of acoustic metamaterials.

2009-01-01

461

Possibilities of rayleigh-taylor instability measurement by X-ray phase imaging  

International Nuclear Information System (INIS)

X-ray imaging is a very useful plasma diagnostic method. A theoretical analysis of the x-ray phase imaging in the method based on Fresnel diffraction is given. The authors show it is a linear band pass filter, a property suit for Rayleigh-Taylor (R-T) instability measurement. The evaluation permits the possibility of R-T instability measurement in x-ray phase imaging

466

MR imaging of musculoskeletal trauma to the pelvis and the lower limb  

Energy Technology Data Exchange (ETDEWEB)

Magnetic resonance imaging can be used in the trauma setting to detect fractures and associated soft tissue injuries of the musculoskeletal system. Magnetic resonance imaging complements plain radiography and CT for evaluating cancellous bone, cartilage and growth-plate injuries, and intra- and extraarticular supporting soft tissue structures. This review outlines typical applications and imaging consideration for injuries of the pelvis and lower extremity. (orig.) With 12 figs., 78 refs.

1999-03-01

468

Lead-203 for skeletal imaging  

International Nuclear Information System (INIS)

... biological variability body distribution kidneys labelled compounds lead 203

469

Knowledge-based image analysis: some aspects on the analysis of images using other types of information  

Energy Technology Data Exchange (ETDEWEB)

The computer vision approach to image analysis is discussed from two aspects. First, this approach is constrasted to the pattern recognition approach. Second, how external knowledge and information and models from other fields of science and engineering can be used for image and scene analysis is discussed. In particular, the connections between computer vision and computer graphics are pointed out.

1982-01-01

471

Introduction to Three Dimensional Reconstruction of Brain C. T. Image  

International Nuclear Information System (INIS)

The reconstruction of coronal and Sagittal Image of Brain C. T. is helpful to diagnosis of Brain. Three Dimensional Reconstruction software package allows to display three dimensional Image clerived from a series of Horizontal, Sagittal and Coronal Brain C. T. images. It useful in determine approach of operation, to define portals of deep radiation therapy.

1986-11-01

479

Fundamental study on Fuji Computed Radiography (FCR) image  

International Nuclear Information System (INIS)

Japanese (Mar 1986). Japan Tomiyoshi, Tsukasa Kakoi, Iwao Fukushima,

1986-01-01

482

Eddy current imaging  

Energy Technology Data Exchange (ETDEWEB)

Image representations have gained wide acceptance in displaying data collected during optical, ultrasonic, radiographic, and thermographic inspections. Applying imaging techniques to eddy current testing is explored in this article. The authors show that flaw interpretation and characterization are made considerably simpler when images are used to visualize the impedance changes in eddy current probes.

1993-04-01

495

A submillimeter wavelength space-based imaging radar  

Science.gov (United States)

This report considers the use of a submillimeter wavelength space-based imaging radar. The main application envisioned is midcourse decoy discrimination for strategic defense, for which it would have the capability of producing a series of images, in real time, at strategic ranges, with less than meter scale resolution and with modest power requirements. Undoubtedly, there are other applications. The requirements for a SAR and ISAR imaging radar at submillimeter wavelength are determined, and the prospect for the development of RF sources to power the radar is examined.

1988-05-01

497

X-ray imaging dose due to the digital imaging devices used in radiation therapy for patient positioning and repositioning: How to take it into account?; Les doses dues a l'imagerie numerique pour le controle de positionnement du patient en radiotherapie: comment les prendre en compte?  

Energy Technology Data Exchange (ETDEWEB)

The patient positioning and repositioning control in radiation therapy all along the treatment can be conducted using a variety of X-ray sources and imaging detector devices. The development of image guided radiation therapy techniques leads to more frequent use of this imaging control. In this article we summarize the current methods for measuring the dose delivered by X-ray imaging devices used in radiation therapy, as well as basic proposals to take account of these imaging doses for prescribing, recording and reporting radiation therapy treatment. (authors)

2008-12-15

498

Utilization of fractional Brownian motion in constrained least-squares restoration of medical images  

International Nuclear Information System (INIS)

Constrained least-squares techniques have been used to produce a well known class of image restoration algorithms. These techniques typically involve minimizing a linear operator on a vector representation of an image, subject to a constraint. For cases where an equality constraint is appropriate the method of Lagrange multipliers can be used to produce a restored image. In this work a fractal textural model, fractional Brownian motion, is used to represent images of interest. Using a variance fractal dimension estimator a non-linear operator, that represents the squared difference between the fractal dimension of the restored image and on a priori value is minimized, subject to the constraint that the norm of the residual between the restored image and available measurement equal the norm of the additive noise.

499

Document image retrieval with morphology-based segmentation and features combination  

Science.gov (United States)

Digital libraries need more than just a retrieval based on keywords, which can be inefficient for some applications. Thus, a document retrieval based on content of the digitized image version of the document can be a more appropriated approach. This paper discusses the retrieval of document images by means of identifying a variety of elements present in the document's image body. We propose a new strategy to identify and combine features extracted from a document image. We also consider the task of constructing an optimized feature set to improve the retrieval performance and to validate our experiments on an assorted database. Experimental results show that the proposed segmentation together with a wisely feature combination increase the overall retrieval performance. Moreover the retrieved images demonstrate the generality and effectiveness of our approach for an efficient ...

2011-01-01

500

Comparative evaluation of /sup 99m/Tc GH, /sup 99m/TcO_4, and /sup 99m/Tc DTPA as brain imaging agents  

International Nuclear Information System (INIS)

The brain imaging properties of /sup 99m/Tc glucoheptonate, /sup 99m/Tc pertechnetate, and /sup 99m/Tc DPTA are compared. Results demonstrate that optimum images are obtained at 90, 180, and 180 min., for /sup 99m/Tc GH, /sup 99m/Tc DTPA, and /sup 99m/Tc pertechnetate, respectively. The former two images are not affected by prior bone imaging with /sup 99m/Tc pyrophosphate, while /sup 99m/Tc pertechnetate images are adversely affected. /sup 99m/Tc glucoheptonate appears to be the superior agent for brain imaging, followed by /sup 99m/Tc DTPA and /sup 99m/Tc pertechnetate.